WorldWideScience

Sample records for basic exploratory research

  1. Exploratory research and development FY90

    International Nuclear Information System (INIS)

    In general, the Exploratory Research and Development (ER ampersand D) Program supports research projects considered too basic or long-range to be funded by other Lawrence Livermore National Laboratory (LLNL) programs. This Program is managed for the Laboratory Director by a special assistant who chairs the LLNL's IR ampersand D Review Committee. Membership in the Review Committee comprises senior LLNL scientists, engineers, and managers whose areas of expertise span the range of scientific disciplines pursued at the Laboratory. The research supported by the Program falls into three categories: Exploratory Research in the Disciplines, Director's Initiatives, and Laboratory-Wide Competition. The first two, Exploratory Research and Director's Initiatives, promote pioneering work in the various scientific disciplines and programmatic areas. Laboratory departments and divisions propose and manage projects in the Exploratory Research category. The Laboratory Director, with the advice of the Review Committee, selects several larger projects to fund as Director's Initiative. These projects, which are proposed and managed by the responsible associate director, are intended to enhance the scope of existing programs or establish new technical directions and programs for the Laboratory. All FY90 projects are described in detail in this report. Other publications on ER ampersand D projects are included in the Publications List at the back of this report

  2. Exploratory research and development FY90

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Middleton, C.; Baldwin, G.; Cherniak, J.; Clements, W.; Donohue, M.L.; Francke, A.; Kirvel, R.D.; MacGregor, P.; Shaw, G. (eds.)

    1990-01-01

    In general, the Exploratory Research and Development (ER D) Program supports research projects considered too basic or long-range to be funded by other Lawrence Livermore National Laboratory (LLNL) programs. This Program is managed for the Laboratory Director by a special assistant who chairs the LLNL's IR D Review Committee. Membership in the Review Committee comprises senior LLNL scientists, engineers, and managers whose areas of expertise span the range of scientific disciplines pursued at the Laboratory. The research supported by the Program falls into three categories: Exploratory Research in the Disciplines, Director's Initiatives, and Laboratory-Wide Competition. The first two, Exploratory Research and Director's Initiatives, promote pioneering work in the various scientific disciplines and programmatic areas. Laboratory departments and divisions propose and manage projects in the Exploratory Research category. The Laboratory Director, with the advice of the Review Committee, selects several larger projects to fund as Director's Initiative. These projects, which are proposed and managed by the responsible associate director, are intended to enhance the scope of existing programs or establish new technical directions and programs for the Laboratory. All FY90 projects are described in detail in this report. Other publications on ER D projects are included in the Publications List at the back of this report.

  3. Basic Research Firing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

  4. Basic Research Objectives Reaffirmed

    Institute of Scientific and Technical Information of China (English)

    Guo Haiyan; Zhao Baohua

    2002-01-01

    @@ As a national institution for scientific research and a component of the national innovation system, CAS should and must make key contributions to the great national rejuvenation of the country. Keeping this in mind, CAS has developed four developmental targets for its basic research. This was revealed at a CAS conference on basic research held June 11-12 in Beijing.

  5. Directed basic research

    International Nuclear Information System (INIS)

    In its execution, and in the requirement of no other deliverables than knowledge generation, directed basic research is no different from conventional (self-directed) basic research. The selected areas are determined in a national perspective. Directed Basic Research may be in an area where the knowledge generation would benefit Indian Society in the long term, or it may be in an area where the results of the research would benefit Indian Industry or our strategic interests in the long term. India can become a global innovation leader provided we have technology foresight to make the right technology choices, provided we introduce coherent synergy (a phrase I coined a few years back in this context) in our science and technology related activities and provided we establish an effective innovation ecosystem. We must also selectively promote some technology areas through directed basic research. Sustainable economic development in the future requires strong and increased funding of basic research. While directed basic research should be encouraged, self-directed basic research should also receive substantially increased support. (author)

  6. Exploratory Research for New Solar Electric Technologies

    Energy Technology Data Exchange (ETDEWEB)

    McConnell, R.; Matson, R.

    2005-01-01

    We will review highlights of exploratory research for new PV technologies funded by the DOE Solar Energy Technologies Program through NREL and its Photovoltaic Exploratory Research Project. The goal for this effort is highlighted in the beginning of the Solar Program Multi-Year Technical Plan by Secretary of Energy Spencer Abraham's challenge to leapfrog the status quo by pursuing research having the potential to create breakthroughs. The ultimate goal is to create solar electric technologies for achieving electricity costs below 5 cents/kWh. Exploratory research includes work on advanced photovoltaic technologies (organic and ultra-high efficiency solar cells for solar concentrators) as well as innovative approaches to emerging and mature technologies (e.g., crystalline silicon).

  7. Exploratory Research and Development Fund, FY 1990

    International Nuclear Information System (INIS)

    The Lawrence Berkeley Laboratory Exploratory R ampersand D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R ampersand D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator and fusion research; applied science; cell and molecular biology; chemical biodynamics; chemical sciences; earth sciences; engineering; information and computing sciences; materials sciences; nuclear science; physics and research medicine and radiation biophysics

  8. Exploratory Research and Development Fund, FY 1990

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    The Lawrence Berkeley Laboratory Exploratory R D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator and fusion research; applied science; cell and molecular biology; chemical biodynamics; chemical sciences; earth sciences; engineering; information and computing sciences; materials sciences; nuclear science; physics and research medicine and radiation biophysics.

  9. Basic research projects

    Energy Technology Data Exchange (ETDEWEB)

    1979-04-01

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined. (RWR)

  10. Basic research projects

    International Nuclear Information System (INIS)

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined

  11. Exploratory Research on Novel Coal

    Energy Technology Data Exchange (ETDEWEB)

    Winschel, R.A.; Brandes, S.D.

    1998-05-01

    The report presents the findings of work performed under DOE Contract No. DE-AC22 -95PC95050, Task 3 - Flow Sheet Development. A novel direct coal liquefaction technology was investigated in a program being conducted by CONSOL Inc. with the University of Kentucky Center for Applied Energy Research and LDP Associates. The process concept explored consists of a first-stage coal dissolution step in which the coal is solubilized by hydride ion donation. In the second stage, the products are catalytically upgraded to refinery feedstocks. Integrated first-stage and solids-separation steps were used to prepare feedstocks for second-stage catalytic upgrading. An engineering and economic evaluation was conducted concurrently with experimental work throughout the program. Parameters were established for a low-cost, low-severity first-stage reaction system. A hydride ion reagent system was used to effect high coal conversions of Black Thunder Mine Wyoming subbituminous coal. An integrated first-stage and filtration step was successfully demonstrated and used to produce product filtrates with extremely low solids contents. High filtration rates previously measured off-line in Task 2 studies were obtained in the integrated system. Resid conversions of first-stage products in the second stage were found to be consistently greater than for conventional two-stage liquefaction resids. In Task 5, elementally balanced material balance data were derived from experimental results and an integrated liquefaction system balance was completed. The economic analysis indicates that the production of refined product (gasoline) via this novel direct liquefaction technology is higher than the cost associated with conventional two-stage liquefaction technologies. However, several approaches to reduce costs for the conceptual commercial plant were recommended. These approaches will be investigated in the next task (Task 4) of the program.

  12. Basic petroleum research. Final report

    International Nuclear Information System (INIS)

    An overview of projects in the field of basic petroleum research (PetroForsk) is presented. A brief presentation of some of the projects is included, as well as political comments on the value of these projects. The research program Basic Petroleum Research (PetroForsk) was established in 1998 and ended in 2004. The program has been part of the Research Council of Norway's long-term effort in petroleum research (ml)

  13. Basic research for environmental restoration

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs

  14. Basic research for environmental restoration

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-01

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs.

  15. Basic statistics for social research

    CERN Document Server

    Hanneman, Robert A; Riddle, Mark D

    2012-01-01

    A core statistics text that emphasizes logical inquiry, notmath Basic Statistics for Social Research teaches core generalstatistical concepts and methods that all social science majorsmust master to understand (and do) social research. Its use ofmathematics and theory are deliberately limited, as the authorsfocus on the use of concepts and tools of statistics in theanalysis of social science data, rather than on the mathematicaland computational aspects. Research questions and applications aretaken from a wide variety of subfields in sociology, and eachchapter is organized arou

  16. Basic Energy Research. Final Report

    International Nuclear Information System (INIS)

    This is the final report of a research programme that covered the need for long-term basic research in Norway within the main fields of new renewable energy sources and hydroelectric power. For the hydropower part, emphasis was placed on the environmental consequences and several projects have been done, with different approaches. Other aspects of hydropower have also been supported, such as dam safety and flow in water paths connected to turbines. Within the field of renewable energies, priority was given to solar energy and bio energy. Research on hydrogen as an energy carrier has also been supported; the programme mainly targeted universities and the research institutes, and the education of PhD's has been a priority. The programme was funded through the Ministry of Petroleum and Energy and the budget was 33 million NOK for the period 1997 - 2000

  17. Research into basic rocks types

    International Nuclear Information System (INIS)

    Teollisuuden Voima Oy (TVO) has carried out research into basic rock types in Finland. The research programme has been implemented in parallel with the preliminary site investigations for radioactive waste disposal in 1991-1993. The program contained two main objectives: firstly, to study the properties of the basic rock types and compare those with the other rock types under the investigation; secondly, to carry out an inventory of rock formations consisting of basic rock types and suitable in question for final disposal. A study of environmental factors important to know regarding the final disposal was made of formations identified. In total 159 formations exceeding the size of 4 km2 were identified in the inventory. Of these formations 97 were intrusive igneous rock types and 62 originally extrusive volcanic rock types. Deposits consisting of ore minerals, industrial minerals or building stones related to these formations were studied. Environmental factors like natural resources, protected areas or potential for restrictions in land use were also studied

  18. EXPLORATORY FACTOR ANALYSIS (EFA IN CONSUMER BEHAVIOR AND MARKETING RESEARCH

    Directory of Open Access Journals (Sweden)

    Marcos Pascual Soler

    2012-06-01

    Full Text Available Exploratory Factor Analysis (EFA is one of the most widely used statistical procedures in social research. The main objective of this work is to describe the most common practices used by researchers in the consumer behavior and marketing area. Through a literature review methodology the practices of AFE in five consumer behavior and marketing journals(2000-2010 were analyzed. Then, the choices made by the researchers concerning factor model, retention criteria, rotation, factors interpretation and other relevant issues to factor analysis were analized. The results suggest that researchers routinely conduct analyses using such questionable methods. Suggestions for improving the use of factor analysis and the reporting of results are presented and a checklist (Exploratory Factor Analysis Checklist, EFAC is provided to help editors, reviewers, and authors improve reporting exploratory factor analysis.

  19. Basic research on maxillofacial implants

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, Yoshiro [Showa Univ., Tokyo (Japan). School of Dentistry

    2001-11-01

    Osseointegrated implants have begun to be used not only in general practice in dentistry but also in various clinical situations in the maxillofacial region. The process has yielded three problems: the spread of application, new materials and diagnostic methods, and management for difficult situations. This paper presents basic data and clinical guidelines for new applications, it investigates the characteristics of the materials and the usefulness of a new diagnostic method, and it studies effective techniques for difficult cases. The results obtained are as follows: Investigations into the spreading application. The lateral and superior orbital rim have sufficient bone thickness and width for the implant body to be placed. Osseointegrated implants, especially by the fixed bridge technique, are not recommended in the craniofacial bone and jaws of young children. Implant placement into bone after/before irradiation must be performed in consideration of impaired osteogenesis, the decrease of trabecular bone, and the time interval between implantation and irradiation. Investigations into materials and diagnostic methods. Hydroxyapatite-coated and titanium implants should be selected according to the characteristics of the materials. A dental simulating soft may also be applicable in the craniofacial region. Investigations into the management of difficult cases. Hyperbaric oxygen therapy (HBO), bone morphogenetic protein (BMP), and tissue engineering should be useful for improving the quality and increasing the quantity of bone where implants are placed. Soft tissue around implants placed in the reconstructed area should be replaced with mucosal tissue. The data obtained here should be useful for increasing the efficiency of osseointegrated implants, but further basic research is required in the future. (author)

  20. Distinguishing between exploratory and confirmatory preclinical research will improve translation.

    Science.gov (United States)

    Kimmelman, Jonathan; Mogil, Jeffrey S; Dirnagl, Ulrich

    2014-05-01

    Preclinical researchers confront two overarching agendas related to drug development: selecting interventions amid a vast field of candidates, and producing rigorous evidence of clinical promise for a small number of interventions. We suggest that each challenge is best met by two different, complementary modes of investigation. In the first (exploratory investigation), researchers should aim at generating robust pathophysiological theories of disease. In the second (confirmatory investigation), researchers should aim at demonstrating strong and reproducible treatment effects in relevant animal models. Each mode entails different study designs, confronts different validity threats, and supports different kinds of inferences. Research policies should seek to disentangle the two modes and leverage their complementarity. In particular, policies should discourage the common use of exploratory studies to support confirmatory inferences, promote a greater volume of confirmatory investigation, and customize design and reporting guidelines for each mode.

  1. Distinguishing between exploratory and confirmatory preclinical research will improve translation.

    Directory of Open Access Journals (Sweden)

    Jonathan Kimmelman

    2014-05-01

    Full Text Available Preclinical researchers confront two overarching agendas related to drug development: selecting interventions amid a vast field of candidates, and producing rigorous evidence of clinical promise for a small number of interventions. We suggest that each challenge is best met by two different, complementary modes of investigation. In the first (exploratory investigation, researchers should aim at generating robust pathophysiological theories of disease. In the second (confirmatory investigation, researchers should aim at demonstrating strong and reproducible treatment effects in relevant animal models. Each mode entails different study designs, confronts different validity threats, and supports different kinds of inferences. Research policies should seek to disentangle the two modes and leverage their complementarity. In particular, policies should discourage the common use of exploratory studies to support confirmatory inferences, promote a greater volume of confirmatory investigation, and customize design and reporting guidelines for each mode.

  2. Basic science research in urology training

    OpenAIRE

    Eberli, D.; Atala, A

    2009-01-01

    The role of basic science exposure during urology training is a timely topic that is relevant to urologic health and to the training of new physician scientists. Today, researchers are needed for the advancement of this specialty, and involvement in basic research will foster understanding of basic scientific concepts and the development of critical thinking skills, which will, in turn, improve clinical performance. If research education is not included in urology training, future urologists ...

  3. Exploratory research into pathogen surface interactions.

    Energy Technology Data Exchange (ETDEWEB)

    Sinclair, Michael B.; Lane, Todd W. (Sandia National Laboratories, Livermore, CA); Jones, Howland D. T.; Rebeil, Roberto; Altman, Susan Jeanne; Kaiser, Julie (Sandia National Laboratories, Livermore, CA); McGrath, Lucas K.; Souza, Caroline Ann

    2006-02-01

    In this short-duration project the research team was able to achieve growth of both drinking water biofilms and monospecific biofilms of Legionella pneurnophila. Preliminary comparative proteomic analyses were carried out on planktonic and biofilm-associated Legionella. After delay for completion of permitting and review by the director of the National Institutes for Allergy and Infectious Disease, the Utah 112 strain of Francisella novicida was obtained and preliminary culture and comparative proteomic analyses were carried out. Comprehensive literature searches and data mining were carried out on all research topics.

  4. Action Research: Some basic issues

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2003-01-01

    The article introduces the main characteristica of action research as well as its origin. In addition the epistmological criteria are presented and discussed. Finally power relationships and ethical concerns are reflected in relation to the practice of action research.......The article introduces the main characteristica of action research as well as its origin. In addition the epistmological criteria are presented and discussed. Finally power relationships and ethical concerns are reflected in relation to the practice of action research....

  5. 32 CFR 37.1240 - Basic research.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Basic research. 37.1240 Section 37.1240 National... TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1240 Basic research. Efforts... practical application of that knowledge and understanding. It typically is funded within...

  6. EXPLORATORY RESEARCH ON NOVEL COAL LIQUEFACTION CONCEPT

    Energy Technology Data Exchange (ETDEWEB)

    Brandes, S.D.; Winschel, R.A.

    1998-11-30

    The report presents a summary the work performed under DOE Contract No. DE-AC22-95PC95050. Investigations performed under Task 4--Integrated Flow Sheet Testing are detailed. In this program, a novel direct coal liquefaction technology was investigated by CONSOL Inc. with the University of Kentucky Center for Applied Energy Research and LDP Associates. The process concept explored consists of a first-stage coal dissolution step in which the coal is solubilized by hydride ion donation. In the second stage, the products are catalytically upgraded to refinery feedstocks. Integrated first-stage and solids-separation steps were used to prepare feedstocks for second-stage catalytic upgrading. An engineering and economic evaluation was conducted concurrently with experimental work throughout the program. Approaches to reduce costs for a conceptual commercial plant were recommended at the conclusion of Task 3. These approaches were investigated in Task 4. The economic analysis of the process as it was defined at the conclusion of Task 4, indicates that the production of refined product (gasoline) via this novel direct liquefaction technology is higher than the cost associated with conventional two-stage liquefaction technologies.

  7. Defending basic research in Europe

    CERN Document Server

    Staff Association

    2010-01-01

    « Research without a budget means a Europe without a future » On Wednesday 25th August 2010, 871 of you signed the Staff Council petition which carried this message. This is a resounding success for a month of August. Staff members and pensioners, you showed by your presence your mass support for our appeal to defend research budgets in Europe. The participation and messages of support from our colleagues in other European scientific organizations is confirmation that budget cuts in research are common practice far beyond the confines of CERN. If research had benefited from the promises made by the European Union in 2000 to increase investment in research and development (R&D) from 1.8% to 3% of GDP by 2010, the scientific community would more readily accept the current cuts. However, we are now in 2010 and the rate of 1.8% has remained the same. So, we have been hit twice: not only have we not had the good weather we were promised, we now find ourselves in the middl...

  8. Denmark lacks coherent policy on basic research

    DEFF Research Database (Denmark)

    Ibba, Michael; Bentin, Thomas

    1999-01-01

    suggest that more critical problems exist that must be addressed immediately to ensure the long-term health of Danish science. Chief among these are a poorly funded and misdirected policy on basic research funding, and conditions of employment that restrict the research opportunities of young scientists....... Danish science is moderately well funded 1 . We have modern facilities, an excellent level of technical support and a buoyant biotechnology sector 2 . What is sorely lacking is a coherent policy on the funding and nurturing of basic research. Entry-level appointments (assistant professor) have a heavy......-equipped to adapt to the rapid development of new areas in basic research. The only surprise is that Danish science has remained so competitive for so long. How long this will continue to be the case is unclear when there is little to attract young scientists. Without a competitive basic research component...

  9. Basic Research Needs for Countering Terrorism

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, W.; Michalske, T.; Trewhella, J.; Makowski, L.; Swanson, B.; Colson, S.; Hazen, T.; Roberto, F.; Franz, D.; Resnick, G.; Jacobson, S.; Valdez, J.; Gourley, P.; Tadros, M.; Sigman, M.; Sailor, M.; Ramsey, M.; Smith, B.; Shea, K.; Hrbek, J.; Rodacy, P.; Tevault, D.; Edelstein, N.; Beitz, J.; Burns, C.; Choppin, G.; Clark, S.; Dietz, M.; Rogers, R.; Traina, S.; Baldwin, D.; Thurnauer, M.; Hall, G.; Newman, L.; Miller, D.; Kung, H.; Parkin, D.; Shuh, D.; Shaw, H.; Terminello, L.; Meisel, D.; Blake, D.; Buchanan, M.; Roberto, J.; Colson, S.; Carling, R.; Samara, G.; Sasaki, D.; Pianetta, P.; Faison, B.; Thomassen, D.; Fryberger, T.; Kiernan, G.; Kreisler, M.; Morgan, L.; Hicks, J.; Dehmer, J.; Kerr, L.; Smith, B.; Mays, J.; Clark, S.

    2002-03-01

    To identify connections between technology needs for countering terrorism and underlying science issues and to recommend investment strategies to increase the impact of basic research on efforts to counter terrorism.

  10. Basic Energy Sciences FY 2011 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-01-01

    This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  11. Basic Energy Sciences FY 2014 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-01-01

    This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  12. Basic Energy Sciences FY 2012 Research Summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-01-01

    This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  13. Peer review, basic research, and engineering: Defining a role for QA professionals in basic research environments

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1989-02-01

    Within the context of doing basic research, this paper seeks to answer four major questions: (1) What is the authority structure of science. (2) What is peer review. (3) Where is the interface between basic physics research and standard engineering. and (4) Given the conclusions to the first three questions, what is the role of the QA professional in a basic research environment like Fermilab. 23 refs.

  14. AECL programs in basic physics research

    International Nuclear Information System (INIS)

    This report describes the CRNL program of research into the basic properties of atomic nuclei and condensed matter (liquids and solids). Brief descriptions are given of some of the current experimental programs done principally at the NRU reactor and MP tandem accelerator, the associated theoretical studies, and some highlights of past achievements

  15. Basic theory research of coal spontaneous combustion

    Institute of Scientific and Technical Information of China (English)

    WANG Ji-ren; SUN Yan-qiu; ZHAO Qing-fu; DENG Cun-bao; DENG Han-zhong

    2008-01-01

    Discussed latest research results of basic theory research of coal spontaneous combustion in detail, with quantum chemical theory and method and experiment systematically studied chemical structure of coal molecule, adsorption mechanism of coal surface to oxygen molecule and chemical reaction mechanism and process of spontaneous combustion of organic macromolecule and low molecular weight compound in coal from microcosmic view, and established complete theoretical system of the mechanism of coal spontaneous combustion.

  16. Basic and Applied Research on Environmental Decisions

    Science.gov (United States)

    Krantz, D. H.

    2006-12-01

    Societal use of well-understood physical or biological science generally involves social processes, including dissemination of the knowledge across society and modification of public policy and of group and individual behavior. The social processes are often poorly understood, from the standpoint of social science; thus, questions in applied natural science often give rise to fundamental questions within social science. For example, problems concerning communication of uncertain scientific information give rise to basic research about how conceptual frameworks (of both the recipients and the providers of such information) change, over the course of repeated attempts at communication. Our Center has been exposed to such communication problems, in several field projects, and this exposure has suggested fruitful new directions for our laboratory research on decision making. For example, we noted (as others have) that communication is often more effective when presented to a group of peers gathered in a familiar setting than to individuals. Among other observations, Orlove and his collaborators noted that Ugandan villagers gather in groups to hear radio broadcasts of climate forecasts together. What behavioral processes lead to more effective communication to groups? Does the social setting enhance individual learning? Does the group frame decision problems differently from the average individual member? Are individual goals modified by the group setting? All three of these processes may be important; we have results concerning each from our current laboratory experiments. I argue that these ideas also require major modification of current theories of decision making, and so are particularly fruitful for basic research in the Decision Sciences. Our experience has led us to emphasize the very close relation between basic and applied social research. We also believe that social-science students need much stronger education in natural sciences and/or engineering, in order

  17. AN EXPLORATORY RESEARCH ON HISTORY OF CLUJ HOTELS

    Directory of Open Access Journals (Sweden)

    Marius BOTA

    2014-12-01

    Full Text Available Cluj-Napoca has a long and interesting history. The City of Cluj is considered the “capital of Transylvania” because it is an important academic, cultural and business center, an interesting tourist destination for various types of tourists. The present study makes an analysis regarding the hotels from Cluj during the 19th and 20th centuries. The analysis is focusing on history of the hotels, their market evolution and the stories related to those hotels. This period was chosen for this research because represent the beginnings of the Cluj hotels market. For the investigations it was used exploratory research, obtaining secondary data through different types of sources: history books, published studies, web sites and old pictures. The present research has two main objectives: the first one is to explore the Cluj history in order to identify the hotels present on the market during the 19th and 20th centuries; the second one is to revile some stories related to the hotels, owners and buildings. There were identified 11 hotels from Cluj during the 19th and 20th centuries. There were not included here the hotels build in the last part of the communist period. At present, the buildings in which were functioned the most important hotels, are on the list of historical monuments from Cluj County. It can be proposed some old pictures and interesting stories about the hotels, the buildings, the guests, in order to attract the tourists.

  18. Basic Skills in the Workplace: A Research Review. Research Report.

    Science.gov (United States)

    Payne, John

    This report analyzes recent English-language research on basic skills in the workplace. Part A, a thematic guide to the field, includes detailed references to publications listed in Part B. Section A1 indicates the scope. It defines basic skills and underlines the importance of other terms, especially key skills, information and communications…

  19. Basic Research Utilities for SBAS (BRUS)

    OpenAIRE

    Prats Menéndez, Xavier; Orús Pérez, Raül; Sanz Subirana, Jaume; Farnworth, Richard; Soley, Santiago

    2003-01-01

    The software package BRUS (Basic Research utilities for SBAS) to process WAAS and EGNOS data is being developed by gAGE/UPC. Some of the main characteristics of BRUS are its architecture design and functionalities that allow to obtain huge information for the different error source components (satellite coordinates, clocks, ionospheric corrections,...), providing wide possibilities for the SBAS performance analysis in both, SIS and position domain. As an application, the performance of the EG...

  20. An Exploratory Research on Structure of Percieved Residential Environment Quality

    Directory of Open Access Journals (Sweden)

    Khosravi Maria

    2016-01-01

    Full Text Available Housing is a composite entity (in the sense of Gary Becker that fulfils several human need. The main need that this commodity is to fulfil is dwelling, but from environmental satisfaction point of view, housing is more than a dwelling unit and its set of objective characteristics, since it also provides health services, security, privacy, neighborhood and social relations, status, community facilities and services, access to jobs and control over the environment. Thus, the principal way in which individual satisfaction with housing is measured through direct questions about their level of housing satisfaction. The purpose of this paper then is to contribute further research on the conceptualization of individual housing satisfaction as a particular domain of satisfaction with life as a whole, providing empirical evidence to disentangle the effects housing characteristics (hedonic, individual and household characteristics (predictive, as well as social interactions originated in one’s residential neighborhood on this housing satisfaction domain. The main contributions of this paper in relation to previous work are the following. First, the simultaneous inclusion of the hedonic and predictive approach in our valuation (by comparing individuals satisfaction and individuals importance values, Second, we also investigate the relations between values in satisfaction and importance. This qualitative exploratory attempt has done by a data gathering through a close ended questionnaire that is made of focus group research.

  1. Exploratory Technology Research Program for electrochemical energy storage

    Science.gov (United States)

    Kinoshita, Kim

    1994-09-01

    The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV's). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EV's. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

  2. Basic methodological preconditions for high quality research

    Directory of Open Access Journals (Sweden)

    Ševkušić Slavica

    2006-01-01

    Full Text Available The paper considers basic methodological preconditions for the qualitative oriented research, in other words, the approaches which in the study of social phenomena rely on theoretical and methodological as well as epistemological premises of a new scientific paradigm. The paper draws special attention to the discussion of criteria of verifiability in qualitative research, which are significantly different from the criteria of positivist approaches. Interpretative research paradigms in social studies have a long history and numerous sources and the very concept of "interpretative shift" consists of a number of different research approaches unified under the name of qualitative methodology. The aim of the paper is not to prove that traditional and new paradigms and quantitative and qualitative research approaches based on them are incompatible in the process of discovering pedagogical reality. The intention is to demonstrate that the complexity of social phenomena requires a complex methodology meaning a complementary use of methods and techniques from both research approaches. The study of qualitative methodological approaches and their application in research, discovery and change of pedagogical reality are particularly important because they may provide new insights into pedagogical reality and a new view of old problems. .

  3. Basic human values in a young group: advances in exploratory study

    Directory of Open Access Journals (Sweden)

    Lilian R. Daset Carreto

    2015-09-01

    Full Text Available This work is part of a wide area of Study, developed since 1998 and focused on Childhood and Adolescence. At first, the aim was to research the psychopathological profile of adolescents, with sociodemographic variables. Further on Competence, Coping and Values were added for an approach from the Positive Psychology (Dahlsgaard, Peterson & Seligman, 2005. This article presents the preliminar results of a youth sample of secondary level students (n=152, aged 12 to 18, male and female, belonging to a medium socioeconomical status. The instrument used for the study is the Basic Values Questionnaire, developed by Valdiney V. Gouveia (1998, based on the studies of S. Schwartz and W. Bilsky (1987, 1990, 2004. Once the performance of this instrument was tested with our Spanish speaking population, some linguistic adaptations were implemented. To obtain the profile of the interviewed adolescents, descriptive statistic is used. The results show to statistically significant difference between girls and boys in Experimenting and Realization Values (Personnel Values Group; as well in Existence (Central Category Value and in Normative (Social Value, with bigger M quantity in Suprapersonnel Value (Central Value and Interaction (Social Category Value. In response to open questions about the most and the least important values, subjects have chosen Interaction (Social Value and Existence Values (Central Value as the most important ones, and Realization Values (Personal Value and the Normative Values (Central Value Category, as the least important ones. The study shows the importance of some groups of Values, what would require an analysis in relation to the behaviours with those that are expressed and their cultural relevance. The conclusions open the debate, from the own expression of the value and their relationship with the psychopathology and on the other hand with the well-being. 

  4. Basic Research Tools for Earthworm Ecology

    Directory of Open Access Journals (Sweden)

    Kevin R. Butt

    2010-01-01

    Full Text Available Earthworms are responsible for soil development, recycling organic matter and form a vital component within many food webs. For these and other reasons earthworms are worthy of investigation. Many technologically-enhanced approaches have been used within earthworm-focused research. These have their place, may be a development of existing practices or bring techniques from other fields. Nevertheless, let us not overlook the fact that much can still be learned through utilisation of more basic approaches which have been used for some time. New does not always equate to better. Information on community composition within an area and specific population densities can be learned using simple collection techniques, and burrowing behaviour can be determined from pits, resin-insertion or simple mesocosms. Life history studies can be achieved through maintenance of relatively simple cultures. Behavioural observations can be undertaken by direct observation or with low cost webcam usage. Applied aspects of earthworm research can also be achieved through use of simple techniques to enhance population development and even population dynamics can be directly addressed with use of relatively inexpensive, effective marking techniques. This paper seeks to demonstrate that good quality research in this sphere can result from appropriate application of relatively simple research tools.

  5. Basic Science Research and the Protection of Human Research Participants

    Science.gov (United States)

    Eiseman, Elisa

    2001-03-01

    Technological advances in basic biological research have been instrumental in recent biomedical discoveries, such as in the understanding and treatment of cancer, HIV/AIDS, and heart disease. However, many of these advances also raise several new ethical challenges. For example, genetic research may pose no physical risk beyond that of obtaining the initial blood sample, yet it can pose significant psychological and economic risks to research participants, such as stigmatization, discrimination in insurance and employment, invasion of privacy, or breach of confidentiality. These harms may occur even when investigators do not directly interact with the person whose DNA they are studying. Moreover, this type of basic research also raises broader questions, such as what is the definition of a human subject, and what kinds of expertise do Institutional Review Boards (IRBs) need to review the increasingly diverse types of research made possible by these advances in technology. The National Bioethics Advisory Commission (NBAC), a presidentially appointed federal advisory committee, has addressed these and other ethical, scientific and policy issues that arise in basic science research involving human participants. Two of its six reports, in particular, have proposed recommendations in this regard. "Research Involving Human Biological Materials: Ethical and Policy Guidance" addresses the basic research use of human tissues, cells and DNA and the protection of human participants in this type of research. In "Ethical and Policy Issues in the Oversight of Human Research" NBAC proposes a definition of research involving human participants that would apply to all scientific disciplines, including physical, biological, and social sciences, as well as the humanities and related professions, such as business and law. Both of these reports make it clear that the protection of research participants is key to conducting ethically sound research. By ensuring that all participants in

  6. Alternatives to animal experimentation in basic research.

    Science.gov (United States)

    Gruber, Franz P; Hartung, Thomas

    2004-01-01

    In contrast to animal testing required by law to guarantee minimum safety standards for the licensing of drugs and chemicals, there are no regulations in basic research forcing scientists to perform animal tests. By (usually) free choice, questions are posed and hypotheses are examined which, in many cases, can only be answered by means of animal tests. Just as easily, different questions could be asked or different hypotheses could be examined which do not require animal tests. The only criterion for the choice of a topic is its relevance which cannot necessarily be judged in the short-term. Thus, it is up to the individual scientist to judge what is worth studying and therefore worth animal consumption. The educated mind will consider ethical aspects of this choice. However, on the other hand, this decision is largely influenced by questions of efficacy or (in a negative sense) by the obstacles posed to an animal consuming approach. Here, peer review and general attitude will strongly influence the methodology chosen. Availability and awareness of adequate in vitro techniques represent the prerequisites for the use of alternative methods. The least one can do in basic research is to avoid tests which cause severe suffering to animals, as is required in Switzerland and other European countries by binding ethical principles and guidelines. The increasing standard of approval and control procedures has improved the situation over the years. There are many examples of successful alternative methods in basic research. But, the application of such methods is in most cases limited to the laboratories in which they were developed, calling for technology transfer. Exceptions are procedures that are used worldwide, like the production of monoclonal antibodies, which instead of using the ascites mouse can also be performed in vitro with some good will. In these cases, commercialisation of the techniques has aided their spread within the scientific community. Sadly, many

  7. Basic research challenges in crystalline silicon photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Werner, J.H. [Max-Planck-Institut fuer Festkoerperforschung, Stuttgart (Germany)

    1995-08-01

    Silicon is abundant, non-toxic and has an ideal band gap for photovoltaic energy conversion. Experimental world record cells of 24 % conversion efficiency with around 300 {mu}m thickness are only 4 % (absolute) efficiency points below the theoretical Auger recombination-limit of around 28 %. Compared with other photovoltaic materials, crystalline silicon has only very few disadvantages. The handicap of weak light absorbance may be mastered by clever optical designs. Single crystalline cells of only 48 {mu}m thickness showed 17.3 % efficiency even without backside reflectors. A technology of solar cells from polycrystalline Si films on foreign substrates arises at the horizon. However, the disadvantageous, strong activity of grain boundaries in Si could be an insurmountable hurdle for a cost-effective, terrestrial photovoltaics based on polycrystalline Si on foreign substrates. This talk discusses some basic research challenges related to a Si based photovoltaics.

  8. [Basic research overview in rheumatoid arthritis].

    Science.gov (United States)

    Iwasaki, Yukiko; Yamamoto, Kazuhiko

    2016-06-01

    Rheumatoid arthritis (RA) is a common autoimmune disease with a prevalence of 0.5-1.0% worldwide. Although advances in understanding the pathogenesis of RA have led to new therapeutics with good outcomes, the real cause of the disease is still unknown. RA is characterized by synovial inflammation and hyperplasia, which erodes cartilage and bone, and autoantibody production (rheumatoid factor (RF) and anti-citrullinated protein antibody (ACPA)). There are many critical questions on the mechanism of the disease onset and progression: How genetic and environmental factors interact with each other? Why does the inflammatory response localize in joints? What are the key players to perpetuate synovial inflammation? In this review, we summarize pathogenetic advances in these issues especially from the point of view of basic research.

  9. Researching Primary Engineering Education: UK Perspectives, an Exploratory Study

    Science.gov (United States)

    Clark, Robin; Andrews, Jane

    2010-01-01

    This paper draws attention to the findings of an exploratory study that critically identified and analysed relevant perceptions of elementary level engineering education within the UK. Utilising an approach based upon grounded theory methodology, 30 participants including teachers, representatives of government bodies and non-profit providers of…

  10. Basic and applied research program. Semiannual report, July-December 1978

    Energy Technology Data Exchange (ETDEWEB)

    Butler, B.L. (ed.)

    1979-12-01

    The status of research projects in the Basic and Applied Research Program at SERI is presented for the semiannual period ending December 31, 1978. The five tasks in this program are grouped into Materials Research and Development, Materials Processing and Development, Photoconversion Research, Exploratory Research, and Energy Resource and Assessment and have been carried out by personnel in the Materials, Bio/Chemical Conversion, and Energy Resource and Assessment Branches. Subtask elements in the task areas include coatings and films, polymers, metallurgy and corrosion, optical materials, surfaces and interfaces in materials research and development; photochemistry, photoelectrochemistry, and photobiology in photoconversion; thin glass mirror development, silver degradation of mirrors, hail resistance of thin glass, thin glass manufacturing, cellular glass development, and sorption by desiccants in materials processing and development; and thermoelectric energy conversion, desiccant cooling, photothermal degradation, and amorphous materials in exploratory research. For each task or subtask element, the overview, scope, goals, approach, apparatus and equipment, and supporting subcontracts are presented, as applicable, in addition to the status of the projects in each task or subtask. Listing of publications and reports authored by personnel associated with the Basic and Applied Research Program and prepared or published during 1978 are also included.

  11. Radiation imaging for basic and applied research

    International Nuclear Information System (INIS)

    To peer into the interiors of a microscopic and macroscopic objects has been the dream of scientist and engineers for centuries. New frontiers in research and development in many branches of science and engineering such as biology, chemistry, engineering, geology, medical or physics have evolved around visual representation of the measurable property of an object, or phenomenon. Visualization using optical radiations provide limited information and often to look into the interiors of microscopic and macroscopic objects, probing with radiations such as x-ray or neutron is required. Such radiations are not directly visible and in order to unravel the data and images unfolded by such radiations, use of luminescent materials which convert these radiations into visible spectrum is required. Radiation imaging techniques have evolved in last few years and with this, new applications in the field of basic and applied sciences have developed. This has put greater demand on the development of new phosphors and scintillators suited for specific applications. This paper reviews new developments in radiation imaging techniques and applications and highlight the use of various phosphors and scintillators for such applications. As the subject is vast, only a few selected topics will be discussed on which work is being carried out at BARC. (author)

  12. Exploratory Research and Development Fund, FY 1990. Report on Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    The Lawrence Berkeley Laboratory Exploratory R&D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R&D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator and fusion research; applied science; cell and molecular biology; chemical biodynamics; chemical sciences; earth sciences; engineering; information and computing sciences; materials sciences; nuclear science; physics and research medicine and radiation biophysics.

  13. Basic and technical research on lung cancer

    International Nuclear Information System (INIS)

    In association with clinical study of carbon beam therapy for lung cancer, the basic research for lung cancer and the patients with this disease has been carried out for the past 10 years. With regard to lung damage by the carbon beams, firstly pulmonary function was measured and analyzed for the patients with stage I non-small cell lung cancer. Force expiratory volume in 1 second (FVE 1.0) and TLC (total lung capacity) was found to be reduced significantly at 6 and 12 months after therapy but the reduction rate was a little, which can support the safety of this treatment modality. Secondly, the regional lung damage by the beams was investigated by using correct fusion of CT images with carbon beam dose distribution, diagnostic follow-up CT images and blood flow and ventilation spect images. It demonstrated the graded decrease blood flow by dose and the compensatory increase of blood flow in the adjacent lobe of lung unexposed to irradiation. On the other hand, the biological study of carbon beam effects on lung cancer cells and tumors line was conducted. Firstly, by using 7 or 4 human lung cancer cell line, the radiosensitivity of carbon beams was compared with that of photons by different histological patterns. It was found that there was no essential difference in the sensitivity pattern for lung cancer histology between the carbon beams and photons though the former doubled the later in power. Secondly, by using IA cell lines among them, the dynamic of clonogenic cells (clonogen) in a nude tumor and the changes in its morphology following irradiation was investigated, clarifying that the clonogen proliferating under anoxic or hypoxic conditions played a pivotal role for tumor regrowth and stemmed from the different clone which had been genetically selected and developed under these conditions. The finding of clonogen becomes one of the evidence supporting the superiority of a single-dose radiotherapy to fractionated radiotherapy. (author)

  14. Basic research in the field of thermal infrared remote sensing

    Institute of Scientific and Technical Information of China (English)

    徐冠华

    2000-01-01

    This overview paper points out that one of the problems impeding further development of remote sensing is that not much attention has been paid to basic research. Key contents of basic research in remote sensing, including modeling, inversion, scaling and scientific experiments, are reviewed. Significance of basic research is demonstrated through summarizing the intentions and progress of the project "Quantitative Remote Sensing Research on Land Surface Energy Exchange".

  15. Basic research in the field of thermal infrared remote sensing

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This overview paper points out that one of the problems impeding further development of remote sensing is that not much attention has been paid to basic research.Key contents of basic research in remote sensing,including modeling,inversion,scaling and scientific experiments,are reviewed.Significance of basic research is demonstrated through summarizing the intentions and progress of the project "Quantitative Remote Sensing Research on Land Surface Energy Exchange".

  16. Multilevel Exploratory Factor Analysis: Illustrating Its Surplus Value in Educational Effectiveness Research

    Science.gov (United States)

    D'Haenens, Ellen; Van Damme, Jan; Onghena, Patrick

    2010-01-01

    This paper illustrates the surplus value of multilevel exploratory factor analysis in educational effectiveness research. Educational researchers often use measures for process variables at the class or school level to explain differences in student outcomes. Recently, van de Vijver and Poortinga (2002) have developed a procedure for multilevel…

  17. Research on Standardization of Basic Meteorological Information

    Institute of Scientific and Technical Information of China (English)

    Wang Chunhu

    2011-01-01

    Current Development of National Meteorological Information Network The national meteorological information network (NMIN) is one of the most important information systems in China's basic meteorological business.Through the construction and development for more than 60 years,the national meteorological information network is beginning to take shape now.The core network in national level has been basically formed,which combines ground wideband network with aerospace satellite communications network all over the country,and the local networks of meteorological departments in different levels have also been developed.

  18. Some Basic Techniques in Bioimpedance Research

    Science.gov (United States)

    Martinsen, Ørjan G.

    2004-09-01

    Any physiological or anatomical changes in a biological material will also change its electrical properties. Hence, bioimpedance measurements can be used for diagnosing or classification of tissue. Applications are numerous within medicine, biology, cosmetics, food industry, sports, etc, and different basic approaches for the development of bioimpedance techniques are discussed in this paper.

  19. Retrieval and exploratory search in multivariate research data repositories using regressional features

    OpenAIRE

    Scherer, Maximilian; Bernard, Jürgen; Schreck, Tobias

    2011-01-01

    Increasing amounts of data are collected in many areas of research and application. The degree to which this data can be accessed, retrieved, and analyzed is decisive to obtain progress in fields such as scientific research or industrial production. We present a novel method supporting content-based retrieval and exploratory search in repositories of multivariate research data. In particular, functional dependencies are a key characteristic of data that researchers are often interested in. Ou...

  20. Safety research basic plan of JNC

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Japan Nuclear Cycle Development Institute (JNC) formally succeeded to Power Reactor and Nuclear Fuel Development Corporation (PNC) on October, 1 1998. This report describes the basic plan for major program of JNC which consists of two parts: management philosophy of the new institute and the latest revised medium term program. In the first part, the primary mission of JNC is to perform its R and D concentrating on fast breeder reactor and its fuel cycle, and treatment and disposal of high-level radioactive wastes, while at the same time giving special consideration to safety. In the second, individual programs in the new basic plan are discussed in detail. The outline and schedule of each program are also attached in the table form. (H. Itami)

  1. Basic research on cancer related to radiation associated medical researches

    International Nuclear Information System (INIS)

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed

  2. Basic research on cancer related to radiation associated medical researches

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon [and others

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed.

  3. Action Research as an Approach to Integrating Sustainability into MBA Programs: An Exploratory Study

    Science.gov (United States)

    Benn, Suzanne; Dunphy, Dexter

    2009-01-01

    This article reports on an exploratory project that employed an action research approach to integrating sustainability into core subjects in the MBA program at an Australian university. It documents the change methodology used, the theoretical basis for this choice, and the project outcomes. It then identifies some key enabling factors and…

  4. A Contextual Theory of Social Style in Primary Relationships: Exploratory Research.

    Science.gov (United States)

    Snavely, William B.

    A theory proposed in explanation and prediction of a concept of social style--an individual's distinctive pattern of communication behavior as perceived by others--was tested in an exploratory study. The two dimensions of social style (assertiveness and responsiveness) served as criterion variables for the study. The major goal of the research was…

  5. COBRE and the Dilemmas of Basic Research in Education

    Science.gov (United States)

    Fincher, Cameron

    1974-01-01

    Evaluates the activities of the Committee on Basic Research in Education (COBRE), pointing out that its work was based on the premises that basic research is oriented to the academic disciplines, that its outcomes are scientific knowledge as opposed to products or solutions, and that its outcomes are unpredictable. (Author/JM)

  6. China's top 10 events in basic research in 2007

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Under the joint auspices of the Ministry of Sciences & Technology (MOST) and China Association for Science & Technology, more than 1,600 Chinese scholars including CAS and CAE members, chief scientists of the National Basic Research Program (dubbed 973 Program) and directors of national key labs, have voted for China's top 10 events in basic research in 2007.

  7. Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles

    Directory of Open Access Journals (Sweden)

    Hobin Jennifer A

    2012-04-01

    Full Text Available Abstract This report is based on the Federation of American Societies for Experimental Biology’s symposium, “Engaging basic Scientists in Translational Research: Identifying Opportunities, Overcoming Obstacles,” held in Chevy Chase, MD, March 24–25, 2011. Meeting participants examined the benefits of engaging basic scientists in translational research, the challenges to their participation in translational research, and the roles that research institutions, funding organizations, professional societies, and scientific publishers can play to address these challenges.

  8. Basic Research Methods for Librarians, Fifth Edition

    CERN Document Server

    Connaway, Lynn Silipigni

    2010-01-01

    Fifty-nine percent of the respondents to a 2000 survey reported that their master's programs had not adequately prepared them to conduct research, something that has not changed much in the ensuing decade. Yet, many library and information services (LIS) practitioners are routinely called upon to conducted job-related research. Where can they turn for the guidance they need?

  9. Basic research supported by the Office of Basic Energy Sciences, U.S. Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, R.D.

    1995-08-01

    This presentation will outline the basic research activities of the Office of Basic Energy Sciences (BES) of the U.S. Department of Energy. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department`s mission. Of particular focus in the presentation are the research programs, amounting to about $10 million, supported by the Materials Sciences Division and the Chemical Sciences Division which are fairly directly related to electrochemical technologies.

  10. Ten Years of Support for Basic Scientific Research by CONACYT

    Directory of Open Access Journals (Sweden)

    Luis Humberto Fabila Castillo

    2014-01-01

    Full Text Available This paper reviews the results of ten years of support for basic scientific research by the CONACYT. The paper identifies the strongest areas of knowledge in basic science in Mexico and concludes that the institutions where basic science is done are mainly public higher education institutions, followed by also public research centers, while private institutions of higher education and companies carry out almost no research in basic science. Findings show that research on basic science in state universities has grown impressively in recent years, reaching the level of the institutions of higher education of the Federal District. Finally, the implications of these findings as well as the public policies through which support has been granted are discussed.

  11. An exploratory investigation of the influence of publication on translational medicine research

    OpenAIRE

    Thomas Vaughan; Preedy Danielle; Douet Lisa J; Cree Ian A

    2010-01-01

    Abstract Background Changes in clinical practice are brought about by the weight of clinical evidence for and against an intervention. Clinical evidence of efficacy relies on the dissemination of research results, usually by publication in medical journals which is often seen as a pre-requisite for progression of an intervention through further clinical trials or implementation studies. How far has research progressed along the translational pathway? We undertook an exploratory exercise to de...

  12. Basic Project Management Methodologies for Survey Researchers.

    Science.gov (United States)

    Beach, Robert H.

    To be effective, project management requires a heavy dependence on the document, list, and computational capability of a computerized environment. Now that microcomputers are readily available, only the rediscovery of classic project management methodology is required for improved resource allocation in small research projects. This paper provides…

  13. Basic research: Issues with animal experimentations

    OpenAIRE

    Saraf, Shyam K; Vinay Kumaraswamy

    2013-01-01

    In vivo studies using the animals are helpful in developing the treatment strategies as they are important link between the successful in vitro testing and safe human use. Various research projects in the field of fixation of fractures, development of newer biomaterials, chemotherapeutic drugs, use of stem cells in nonunion of fractures and cartilage defects etc., have hugely depended on animal experimentation. The employment of animals in experiments is both scientific and ethical issue. The...

  14. UNIVERSITY BASIC RESEARCH AND APPLIED AGRICULTURAL BIOTECHNOLOGY

    OpenAIRE

    Xia, Yin

    2004-01-01

    I examine the effects of R&D inputs on the subset of life-science outputs which demonstrably has influenced later technology, as evidenced by literature citations in agricultural biotechnology patents. Universities are found to be a principal seedbed for cutting-edge technology development. A university's life-science research budget strongly affects its technology-relevant life-science output as well as graduate education.

  15. Basic research: Issues with animal experimentations.

    Science.gov (United States)

    Saraf, Shyam K; Kumaraswamy, Vinay

    2013-01-01

    In vivo studies using the animals are helpful in developing the treatment strategies as they are important link between the successful in vitro testing and safe human use. Various research projects in the field of fixation of fractures, development of newer biomaterials, chemotherapeutic drugs, use of stem cells in nonunion of fractures and cartilage defects etc., have hugely depended on animal experimentation. The employment of animals in experiments is both scientific and ethical issue. There must be reasonable reasons to show that it will significantly advance the present knowledge and lead to improvement in care. The regulatory bodies exist for humane use and care of animals used for experiments e.g., International Council for Laboratory Animal Science, Council for International Organizations of Medical Sciences, International Union of Biological Sciences, International Committee on Laboratory Animals. In India, Indian National Science Academy, Indian Council of Medical Research, National Centre for Laboratory Animal Sciences promote high standards of laboratory animal quality, care and health. The Committee for the Purpose of Control and Supervision on Experiments on Animals guidelines are well defined and is a must read document for any one interested to carry out research with animal facilities. PMID:23532705

  16. Basic research: Issues with animal experimentations

    Directory of Open Access Journals (Sweden)

    Shyam K Saraf

    2013-01-01

    Full Text Available In vivo studies using the animals are helpful in developing the treatment strategies as they are important link between the successful in vitro testing and safe human use. Various research projects in the field of fixation of fractures, development of newer biomaterials, chemotherapeutic drugs, use of stem cells in nonunion of fractures and cartilage defects etc., have hugely depended on animal experimentation. The employment of animals in experiments is both scientific and ethical issue. There must be reasonable reasons to show that it will significantly advance the present knowledge and lead to improvement in care. The regulatory bodies exist for humane use and care of animals used for experiments e.g., International Council for Laboratory Animal Science, Council for International Organizations of Medical Sciences, International Union of Biological Sciences, International Committee on Laboratory Animals. In India, Indian National Science Academy, Indian Council of Medical Research, National Centre for Laboratory Animal Sciences promote high standards of laboratory animal quality, care and health. The Committee for the Purpose of Control and Supervision on Experiments on Animals guidelines are well defined and is a must read document for any one interested to carry out research with animal facilities.

  17. Research on Internationalisation in Higher Education--Exploratory Analysis

    Science.gov (United States)

    Yemini, Miri; Sagie, Netta

    2016-01-01

    Research on internationalisation in higher education has dramatically expanded over the last several decades. This study aims to provide an overview of the research developments undertaken between 1980 and 2014, on internationalisation in higher education. Explorative, systematic literature screening and analysis were undertaken, encompassing over…

  18. Challenges in Exploratory Methods for Tuberculosis Research in South Africa.

    Science.gov (United States)

    Macdonald, Helen; Abney, Kate; Abrams, Amber; Truyts, Carina

    2016-07-01

    Haunted by a legacy of apartheid governance that left millions in material poverty, South Africa has among the highest tuberculosis (TB) morbidity and mortality rates in the world. Our Social Markers of TB research project shared a vision of working with ethnographic research methods to understand TB-infected persons, their families, care providers, and social networks. We argue that felt and enacted TB stigma and the related HIV-TB stigma impaired our ability to collect the necessary data for a full portrait of TB-infected persons and their lived conditions. To circumvent this limitation, each researcher improvised and augmented conventional anthropological methods with more creative, directed, and at times destabilizing methods. We present three case studies as useful illustrations of the complexities and challenges we encountered in our attempts to conduct ethically sound TB research. We discuss the implications of our call for "improvisation" for the politics of research and ethical oversight. PMID:26443797

  19. Challenges in Exploratory Methods for Tuberculosis Research in South Africa.

    Science.gov (United States)

    Macdonald, Helen; Abney, Kate; Abrams, Amber; Truyts, Carina

    2016-07-01

    Haunted by a legacy of apartheid governance that left millions in material poverty, South Africa has among the highest tuberculosis (TB) morbidity and mortality rates in the world. Our Social Markers of TB research project shared a vision of working with ethnographic research methods to understand TB-infected persons, their families, care providers, and social networks. We argue that felt and enacted TB stigma and the related HIV-TB stigma impaired our ability to collect the necessary data for a full portrait of TB-infected persons and their lived conditions. To circumvent this limitation, each researcher improvised and augmented conventional anthropological methods with more creative, directed, and at times destabilizing methods. We present three case studies as useful illustrations of the complexities and challenges we encountered in our attempts to conduct ethically sound TB research. We discuss the implications of our call for "improvisation" for the politics of research and ethical oversight.

  20. Translating basic research in cancer patient care

    Directory of Open Access Journals (Sweden)

    Marcello Maugeri-Saccà

    2011-01-01

    Full Text Available With the advent of molecular targeted therapies and the development of high-throughput biotechnologies, it has become evident that progress in cancer research is largely due to the creation of multidisciplinary teams able to plan clinical trials supported by appropriate molecular hypotheses. These efforts have culminated in the identification and validation of biomarkers predictive of response, as well as in the generation of more accurate prognostic tools. The identification of cancer stem cells has provided further insights into mechanisms of cancer, and many studies have tried to translate this biological notion into prognostic and predictive information. In this regard, new agents targeting key stemness-related pathways have entered the clinical development, and preliminary data suggested an encouraging antitumor activity.

  1. Basic research needs for management and disposal of DOE wastes

    International Nuclear Information System (INIS)

    This document was chartered by the Department of Energy (DOE), Office of Energy Research. It identifies and describes 87 basic research needs in support of advanced technology for management and disposal of Department of Energy radioactive, hazardous chemical, and mixed wastes. A team of scientists and engineers from several DOE laboratories and sites, from academia, and from industry identified and described the basic research needs called out in this report. Special efforts were made to ensure that basic research needs related to management and disposal of any hazardous chemical wastes generated at nonnuclear DOE sites and facilities were properly identified. It is hoped that scientists in both DOE and nongovernment laboratories and institutions will find this document useful when formulating research efforts relevant to waste management and disposal. For management and disposal of DOE radioactive and mixed wastes, basic research needs are identified in nine separate action areas. Basic research needs for management and disposal of DOE hazardous chemical wastes are identified in five action areas. Sufficient description and background information are provided in the report for each particular research need to enable qualified and imaginative scientists to conceive research efforts and programs that will meet the need. 28 refs., 7 tabs

  2. Rurality Research and Rural Education: Exploratory and Explanatory Power

    Science.gov (United States)

    Balfour, Robert J.

    2012-01-01

    This article presents analysed data from the first year of the Rural Teacher Education Project (RTEP 2007-2009) with a view to illustrating how a generative theory of rurality as education research was developed, and for which ends it might be utilised. The article suggests that data from projects in rural communities, which take the rural as…

  3. Young People's Images of Old Age in Chile: Exploratory Research

    Science.gov (United States)

    Arnold-Cathalifaud, Marcelo; Thumala, Daniela; Urquiza, Anahi; Ojeda, Alejandra

    2008-01-01

    According to gerontological thought, an important part of senior citizens' disabilities are products of their social exclusion rather than factors associated with their physical or mental health. How these exclusions come about was the purpose of the research reported in this article. The study was conducted among 682 Chilean university students…

  4. The Rise of Mp3: Exploratory Study and Research Agenda

    OpenAIRE

    Alturas, Bráulio; Oliveira, Abílio

    2005-01-01

    The Internet/World Wide Web (Web) is an important way for the sharing and selling of products and services, including music, in crescent virtual communities. The MP3 standard is the world’s most popular file format and allows many on-line individuals to access to music which they would otherwise be denied. Although electronic commerce (e-commerce) has received considerable research attention, the literature reveals that the relationship between the music industry and the consumers trough the ...

  5. 基于模型组合的探索性分析方法研究%Research on Exploratory Analysis Based on Model Combination

    Institute of Scientific and Technical Information of China (English)

    刘伟涛; 刘小江; 王俐莉

    2012-01-01

    研究对复杂系统正确建模问题,在运用探索性分析方法解决复杂系统不确定性问题的过程中,探索性分析建模是重点和难点.为了提高探索性分析建模的效率,在分析相关方法的基础上,提出了模型组合的探索性分析方法的基本理论,设计了关于模型组合的探索性分析框架,确定了探索性分析框架的工作流程,给出了探索性分析模型表示及描述,设计了模型库的结构,实现了模型组合功能,并通过要素敏感性分析得到不确定性因素对系统整体的影响程度.提高了探索性分析建模的有效性和适应性,对复杂系统的研究具有一定的借鉴意义.%When Exploratory Analysis is applied to resolve the uncertain problems of complex systems, exploratory analysis modeling is very important and difficult as well. In order to enhance the efficiency of exploratory analysis modeling, based on the analysis of related methods, the basic theory of exploratory analysis based on model combination was proposed, the frame of exploratory analysis based on model combination was designed, the work flow of the frame of exploratory analysis was confirmed, the expression and description to exploratory analysis model was given, the structure of the model base was designed, the function of model combination was realized, and the influencing degree of uncertain factors for the whole system was acquired through factors sensitive analysis. The effectiveness and adaptability of exploratory analysis modeling were enhanced, which has referential significance for research on complex systems.

  6. Exploratory Technology Research Program for electrochemical energy storage. Annual report fr 1994

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. [ed.

    1995-09-01

    The US Department of Energy`s Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EVs). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The general R&D areas addressed by the program include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, establishment of engineering principles applicable to electrochemical energy storage and conversion, and the development of air-system (fuel cell, metal/air) technology for transportation applications. Major emphasis is given to applied research which will lead to superior performance and lower life-cycle costs. The ETR Program is divided into three major program elements: Exploratory Research, Applied Science Research, and Air Systems Research. Highlights of each program element are summarized according to the appropriate battery system or electrochemical research area.

  7. Virtual Exploratories

    DEFF Research Database (Denmark)

    Jensen, Sisse Siggaard

    2006-01-01

    -systems, the paper introduces the designing strategy referred to as virtual exploratories. Some of the advanced virtual worlds may inspire the design of such provoking and challenging virtual exploratories, and especially the Massively Multi-User Online Role-Playing Games (MMORPGS). However, if we have to learn from...... the design and activity of the advanced virtual worlds and role-playing games, then the empirical research on the actors’ activity, while they are acting, is an important precondition to it. A step towards the conception of such a designing strategy for virtual exploratories is currently pursued...... in an ongoing empirical research project ‘Actors and Avatars Communicating in Virtual Worlds’ [1]. This paper presents some of the preliminary findings that exemplify this ongoing empirical research and the methodological approach is briefly introduced, that is...

  8. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    OpenAIRE

    Ali Nouri

    2016-01-01

    The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an inte...

  9. Exploratory Technology Research Program for Electrochemical Energy Storage. Annual report, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. [ed.

    1993-10-01

    This report summarizes the progress made by the Exploratory Technology Research (ETR) Program for Electrochemical Energy Storage during calendar year 1992. The primary objective of the ETR Program, which is sponsored by the US Department of Energy (DOE) and managed by Lawrence Berkeley Laboratory (LBL), is to identify electrochemical technologies that can satisfy stringent performance, durability and economic requirements for electric vehicles (EVs). The ultimate goal is to transfer the most-promising electrochemical technologies to the private sector or to another DOE program (e.g., SNL`s Electric Vehicle Advanced Battery Systems Development Program, EVABS) for further development and scale-up. Besides LBL, which has overall responsibility for the ETR Program, LANL and BNL have participated in the ETR Program by providing key research support in several of the program elements. The ETR Program consists of three major elements: Exploratory Research; Applied Science Research; and Air Systems Research. The objectives and the specific battery and electrochemical systems addressed by each program element are discussed in the following sections, which also include technical summaries that relate to the individual programs. Financial information that relates to the various programs and a description of the management activities for the ETR Program are described in the Executive Summary.

  10. Basic Solar Energy Research in Japan (2011 EFRC Forum)

    International Nuclear Information System (INIS)

    Kazunari Domen, Chemical System Engineering Professor at the University of Tokyo, was the second speaker in the May 26, 2011 EFRC Forum session, 'Global Perspectives on Frontiers in Energy Research.' In his presentation, Professor Domen talked about basic solar energy research in Japan. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss 'Science for our Nation's Energy Future.' In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  11. Gravity Related Research with Aquatic Animals - Overview and Perspectives towards Exploratory Missions

    Science.gov (United States)

    Slenzka, K.

    Gravity related research with aquatic animals has not only a long tradition in manned and unmanned space flight but also in ground based research using clinostats and centrifuges In this presentation an overview will be given starting from the early beginning with such experiments Skylab Apollo-Soyuz etc up to today s flight experiments and ground based studies In addition verification will be presented how this research contributes to Earth s benefits and application as well as an outlook will be given how potential follow-up studies may contribute in manned exploratory missions on Earth Moon Mars and maybe beyond This review will summarize results obtained and will try to transfer them into future perspectives in space exploration

  12. Basic research with low-energy accelerator systems

    International Nuclear Information System (INIS)

    The major important tasks of basic research are to push back the frontiers of scientific knowledge, and to train students. It will be shown that small accelerator facilities are still capable of producing interesting and exciting results that are on the leading edge of scientific inquiry. In addition, I will argue that, although these facilities often cannot afford to train students in the use of the most modern research equipment, there is an important compensating benefit in that they larger facilities. This 'liberal' education, as opposed to 'technical' instruction in the use of the most modern research equipment, may well be of more value to society in the long run. (Author)

  13. Geoengineering: Basic science and ongoing research efforts in China

    Directory of Open Access Journals (Sweden)

    Long Cao

    2015-09-01

    Full Text Available Geoengineering (also called climate engineering, which refers to large-scale intervention in the Earth's climate system to counteract greenhouse gas-induced warming, has been one of the most rapidly growing areas of climate research as a potential option for tackling global warming. Here, we provide an overview of the scientific background and research progress of proposed geoengineering schemes. Geoengineering can be broadly divided into two categories: solar geoengineering (also called solar radiation management, or SRM, which aims to reflect more sunlight to space, and carbon dioxide removal (CDR, which aims to reduce the CO2 content in the atmosphere. First, we review different proposed geoengineering methods involved in the solar radiation management and carbon dioxide removal schemes. Then, we discuss the fundamental science underlying the climate response to the carbon dioxide removal and solar radiation management schemes. We focus on two basic issues: 1 climate response to the reduction in solar irradiance and 2 climate response to the reduction in atmospheric CO2. Next, we introduce an ongoing geoengineering research project in China that is supported by National Key Basic Research Program. This research project, being the first coordinated geoengineering research program in China, will systematically investigate the physical mechanisms, climate impacts, and risk and governance of a few targeted geoengineering schemes. It is expected that this research program will help us gain a deep understanding of the physical science underlying geoengineering schemes and the impacts of geoengineering on global climate, in particular, on the Asia monsoon region.

  14. Geoengineering:Basic science and ongoing research efforts in China

    Institute of Scientific and Technical Information of China (English)

    CAO Long; GAO Chao-Chao; ZHAO Li-Yun

    2015-01-01

    Geoengineering (also called climate engineering), which refers to large-scale intervention in the Earth's climate system to counteract greenhouse gas-induced warming, has been one of the most rapidly growing areas of climate research as a potential option for tackling global warming. Here, we provide an overview of the scientific background and research progress of proposed geoengineering schemes. Geo-engineering can be broadly divided into two categories:solar geoengineering (also called solar radiation management, or SRM), which aims to reflect more sunlight to space, and carbon dioxide removal (CDR), which aims to reduce the CO2 content in the atmosphere. First, we review different proposed geoengineering methods involved in the solar radiation management and carbon dioxide removal schemes. Then, we discuss the fundamental science underlying the climate response to the carbon dioxide removal and solar radiation management schemes. We focus on two basic issues:1) climate response to the reduction in solar irradiance and 2) climate response to the reduction in atmospheric CO2. Next, we introduce an ongoing geoengineering research project in China that is supported by National Key Basic Research Program. This research project, being the first coordinated geoengineering research program in China, will systematically investigate the physical mechanisms, climate impacts, and risk and governance of a few targeted geoengineering schemes. It is expected that this research program will help us gain a deep under-standing of the physical science underlying geoengineering schemes and the impacts of geoengineering on global climate, in particular, on the Asia monsoon region.

  15. Assuring both quality and creativity in basic research

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1990-04-12

    How does one assure that both quality and creativity are obtained in basic research environments QA theoreticians have attempted to develop workable definitions of quality, but in more reflective moments, these definitions often fail to capture the deeper essence of the idea of quality.'' This paper asserts that creativity (as a product of the human mind) is a concrete interface between perfunctory definitions of quality (conformance to specifications) and more philosophical speculations about the nature of quality- related ultimates'' like elegance or beauty. In addition, we describe the distinction between creative ideas and creative acts and highlight one of the major inhibitors of creativity, fear. Finally we show that highly creative people often have an irreverent attitude toward boundaries and established authority, and discuss how one can allow for this when designing a QA program in a basic research environment.

  16. Basic Design of the Cold Neutron Research Facility in HANARO

    International Nuclear Information System (INIS)

    The HANARO Cold Neutron Research Facility (CNRF) Project has been embarked in July 2003. The CNRF project has selected as one of the radiation technology development project by National Science and Technology Committee in June 2002. In this report, the output of the second project year is summarized as a basic design of cold neutron source and related systems, neutron guide, and neutron scattering instruments

  17. Basic Design of the Cold Neutron Research Facility in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hark Rho; Lee, K. H.; Kim, Y. K. (and others)

    2005-09-15

    The HANARO Cold Neutron Research Facility (CNRF) Project has been embarked in July 2003. The CNRF project has selected as one of the radiation technology development project by National Science and Technology Committee in June 2002. In this report, the output of the second project year is summarized as a basic design of cold neutron source and related systems, neutron guide, and neutron scattering instruments.

  18. Basic and clinical researches of parasitosis in China revisited

    Institute of Scientific and Technical Information of China (English)

    JIANG Ci-peng

    2005-01-01

    @@ Two years ago, an editorial regarding basic or clinical studies of several parasitosis in China was published.1 As is known to all, some parasitic diseases, especially schistosomiasis and echino-coccosis, are still prevalent in the south and west of China, respectively. Therefore, it is significant to review a few research papers in the field of medical parasitology and write another editorial.

  19. Report 1984-1985. Department of Basic Research

    International Nuclear Information System (INIS)

    A report is presented of the activities performed by the Department of Basic research of the Bariloche Atomic Center during the period 1984-1985. In this report, works on different subjects related to Physics, are grouped in six sections: Low temperatures, Atomic collisions, Metals, Neutrons and Reactors, Magnetic Resonances and Theory. In addition, a list of publications, made by the Department during said period, is included. (M.E.L.)

  20. Progress report 1986-1987 Basic Research Department

    International Nuclear Information System (INIS)

    A report is presented of the activities performed by the Basic Research Department of the Bariloche Atomic Center during the period 1986-1987. In this report, works on different subjects related to physics are grouped: atomic collisions, low temperatures, magnetic resonance, metals, neutrons and reactors and theoretical physics (computational, elementary particles, nuclear physics and solid states). In addition, Appendix I and II regarding the staff and visiting scientists, respectively, and publications and conferences are included

  1. Basic research in computer science and software engineering at SKLCS

    Institute of Scientific and Technical Information of China (English)

    Jian ZHANG; Xueyang ZHU; Wenhui ZHANG; Naijun ZHAN; Yidong SHEN; Haiming CHEN; Yunquan ZHANG; Yongji WANG; Enhua WU; Hongan WANG

    2008-01-01

    The State Key Laboratory of Computer Science (SKLCS) is committed to basic research in computer sci-ence and software engineering. The research topics of the laboratory include: concurrency theory, theory and algorithms for real-time systems, formal specifications based on context-free grammars, semantics of program-ming languages, model checking, automated reasoning, logic programming, software testing, software process improvement, middleware technology, parallel algo-rithms and parallel software, computer graphics and human-computer interaction. This paper describes these topics in some detail and summarizes some results obtained in recent years.

  2. Basic Energy Research. Final Report; Grunnleggende energiforskning. Sluttrapport

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This is the final report of a research programme that covered the need for long-term basic research in Norway within the main fields of new renewable energy sources and hydroelectric power. For the hydropower part, emphasis was placed on the environmental consequences and several projects have been done, with different approaches. Other aspects of hydropower have also been supported, such as dam safety and flow in water paths connected to turbines. Within the field of renewable energies, priority was given to solar energy and bio energy. Research on hydrogen as an energy carrier has also been supported; the programme mainly targeted universities and the research institutes, and the education of PhD's has been a priority. The programme was funded through the Ministry of Petroleum and Energy and the budget was 33 million NOK for the period 1997 - 2000.

  3. Test Research for Basic Mechanics Performance of Inorganic Polymer Concrete

    Directory of Open Access Journals (Sweden)

    Huihong Liu

    2014-01-01

    Full Text Available The main objective of this study is to evaluate the basic mechanics properties (compressive strength, modulus of elasticity, Poisson’s ratio and splitting tensile strength of inorganic polymer concrete whose mix proportion is ripe recipe and try to provide an experimental and theoretical foundation for application of inorganic polymer concrete in the practical engineering. In this study, the basic mechanics properties of inorganic polymer concrete have been studied by test. At the same time, the same tests researches are made for the common Portland cement concrete for comparison. Through the comparison research, it can be found that the compressive bearing capacity of inorganic polymer concrete is stronger and the modulus of elasticity and Poisson’s ratio is slightly bigger than those of common concrete and that the splitting tensile strength is as poor as those of ordinary Portland cement concrete. In order to investigate its long-term performance, the shrinkage and creep tests of inorganic polymer concrete have been studied as well. The change rules of shrinkage and creep in inorganic polymer concrete with time are obtained. It is that initial deformation is bigger and late deformation gradually becomes small and stable. These rules are basic similar as common Portland cement concrete.

  4. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    Directory of Open Access Journals (Sweden)

    Ali Nouri

    2016-06-01

    Full Text Available The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an interdisciplinary endeavor to develop an insightful understanding and holistic picture of problems related to learning and education. It thus epistemologically is based on an integrated methodological pluralism paradigm. This requires researchers to understand multiple methods and methodologies and employ as they formulate their own research projects. Researchers have a critical role to play in providing systematic evidence and conclusions that are scientifically valid and reliable and educationally relevant and usable. One significant implication of this argument is the need to strengthen the quality of the research component in graduate programs of the field and train interested researchers in the identification and formulation of relevant research questions.

  5. [Basic theory and research method of urban forest ecology].

    Science.gov (United States)

    He, Xingyuan; Jin, Yingshan; Zhu, Wenquan; Xu, Wenduo; Chen, Wei

    2002-12-01

    With the development of world economy and the increment of urban population, the urban environment problem hinders the urban sustainable development. Now, more and more people realized the importance of urban forests in improving the quality of urban ecology. Therefore, a new subject, urban forest ecology, and correlative new concept frame in the field formed. The theoretic foundation of urban forest ecology derived from the mutual combination of theory relating to forest ecology, landscape ecology, landscape architecture ecology and anthrop-ecology. People survey the development of city from the view of ecosystem, and regard the environment, a colony of human, animals and plants, as main factors of the system. The paper introduces systematically the urban forest ecology as follows: 1) the basic concept of urban forest ecology; 2) the meaning of urban forest ecology; 3) the basic principle and theoretic base of urban forest ecology; 4) the research method of urban forest ecology; 5) the developmental expectation of urban forest ecology.

  6. The Romanian Consumer And Online Marketing – An Exploratory Research Approach

    Directory of Open Access Journals (Sweden)

    Pantea Carmen

    2008-04-01

    Full Text Available In recent decades, online marketing has been quickly overtaking the traditional means of marketing due to several reasons, such as: low costs, the growing number of internet users and the long lasting relationship developed with them, the effortless usage of the web and of the online marketing tools. Online marketing is done by those individuals or organizations which exchange ideas and offers by using computers, online networks and interactive media, in order to reach their marketing objectives. The results of an exploratory research in terms of the consumers’ exposure, their behavior in relationship with the specific campaigns oriented toward them and the future of the online and offline direct communication at the level of the pre-defined target segments are presented in a comparative manner: online versus offline direct communication tools.

  7. Research and Analysis of Exploratory Software Testing%探索性软件测试解析

    Institute of Scientific and Technical Information of China (English)

    李军锋; 栾静

    2011-01-01

    Exploratory testing is a new software test technology which is totally different from traditional software test methods. Exploratory Testing is defined as concurrent product exploration test design and test execution, and it claims to embrace change. Since the exploratory testing can find software Bugs with high efficiency, it is widely researched. This paper from the shortage of the traditional software test method model theories, carried on overall researching and analysis to the exploratory testing's definition, model,method, merit and shortcoming etc. The researching shows that exploratory testing method is to the very good complement of the theories of the traditional software test, making use of exploratory testing rationally, can enhance the software testing efficiency evidently.%探索性测试是一种完全不同于传统测试方法的测试技术,它提出将学习被测系统、设计测试用例、执行测试同时进行的策略,以及拥抱变化的口号.探索性测试由于其高效的发现软件缺陷的能力而越来越受到人们的重视.文章由传统软件测试方法模型理论的不足,引出探索性软件测试这种前沿的软件测试理论,对其定义、模型方法及优缺点等进行了全面的研究分析.研究表明探索性软件测试方法是对传统软件测试理论的很好补充,合理的利用探索性测试,能够显著提高软件的测试效率.

  8. The benefits of basic research: advances in reproductive physiology.

    Science.gov (United States)

    1995-06-01

    At the Population Council's Center for Biomedical Research basic research is being conducted on the reproductive system with a view to develop new contraceptive and reproductive health technologies. Research in the Reproductive Physiology Program at the Center is carried out by reproductive endocrinologists, molecular biologists, and biochemists working in eight laboratories. In several of the laboratories the function of hormones that regulate spermatogenesis is studied. Scientists in Milan Bagchi's laboratory have developed a model system, composed of cellular components in a test tube, that allows them to study the full sequence of events involved in signal transduction. In James Catterall's laboratory, scientists study how androgens regulate sexual development at the molecular level. The steroid hormones cortisol and corticosterone play critical roles in mammalian fetal development. Scientists in several laboratories study the function of two specialized testicular cells: the Leydig and Sertoli cells. The Leydig cell synthesizes and secretes testosterone, an androgen that regulates spermatogenesis. The Sertoli cell maintains the environment in which spermatogenesis occurs. Researchers in Glen Gunsalus's laboratory study an androgen-binding protein secreted by the Sertoli cell. In collaboration with scientists at the Shanghai Research Center of Biotechnology, they used advanced genetic techniques to create a biologically active form of the protein in silk worm larvae. Scientists in Patricia Morris's laboratory recently identified molecular signals that control the interactions between developing sperm and Sertoli and Leydig cells. In the laboratory of David Phillips, scientists are investigating how the HIV virus penetrates the outer layer of cells in the genital tract and infects underlying cells. In 1994 a vaginally applied microbicide was developed that may inhibit infection by sexually transmitted diseases including HIV. Applications of basic research such

  9. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.

    Science.gov (United States)

    Green, Robert C; Goddard, Katrina A B; Jarvik, Gail P; Amendola, Laura M; Appelbaum, Paul S; Berg, Jonathan S; Bernhardt, Barbara A; Biesecker, Leslie G; Biswas, Sawona; Blout, Carrie L; Bowling, Kevin M; Brothers, Kyle B; Burke, Wylie; Caga-Anan, Charlisse F; Chinnaiyan, Arul M; Chung, Wendy K; Clayton, Ellen W; Cooper, Gregory M; East, Kelly; Evans, James P; Fullerton, Stephanie M; Garraway, Levi A; Garrett, Jeremy R; Gray, Stacy W; Henderson, Gail E; Hindorff, Lucia A; Holm, Ingrid A; Lewis, Michelle Huckaby; Hutter, Carolyn M; Janne, Pasi A; Joffe, Steven; Kaufman, David; Knoppers, Bartha M; Koenig, Barbara A; Krantz, Ian D; Manolio, Teri A; McCullough, Laurence; McEwen, Jean; McGuire, Amy; Muzny, Donna; Myers, Richard M; Nickerson, Deborah A; Ou, Jeffrey; Parsons, Donald W; Petersen, Gloria M; Plon, Sharon E; Rehm, Heidi L; Roberts, J Scott; Robinson, Dan; Salama, Joseph S; Scollon, Sarah; Sharp, Richard R; Shirts, Brian; Spinner, Nancy B; Tabor, Holly K; Tarczy-Hornoch, Peter; Veenstra, David L; Wagle, Nikhil; Weck, Karen; Wilfond, Benjamin S; Wilhelmsen, Kirk; Wolf, Susan M; Wynn, Julia; Yu, Joon-Ho

    2016-06-01

    Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine. PMID:27181682

  10. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.

    Science.gov (United States)

    Green, Robert C; Goddard, Katrina A B; Jarvik, Gail P; Amendola, Laura M; Appelbaum, Paul S; Berg, Jonathan S; Bernhardt, Barbara A; Biesecker, Leslie G; Biswas, Sawona; Blout, Carrie L; Bowling, Kevin M; Brothers, Kyle B; Burke, Wylie; Caga-Anan, Charlisse F; Chinnaiyan, Arul M; Chung, Wendy K; Clayton, Ellen W; Cooper, Gregory M; East, Kelly; Evans, James P; Fullerton, Stephanie M; Garraway, Levi A; Garrett, Jeremy R; Gray, Stacy W; Henderson, Gail E; Hindorff, Lucia A; Holm, Ingrid A; Lewis, Michelle Huckaby; Hutter, Carolyn M; Janne, Pasi A; Joffe, Steven; Kaufman, David; Knoppers, Bartha M; Koenig, Barbara A; Krantz, Ian D; Manolio, Teri A; McCullough, Laurence; McEwen, Jean; McGuire, Amy; Muzny, Donna; Myers, Richard M; Nickerson, Deborah A; Ou, Jeffrey; Parsons, Donald W; Petersen, Gloria M; Plon, Sharon E; Rehm, Heidi L; Roberts, J Scott; Robinson, Dan; Salama, Joseph S; Scollon, Sarah; Sharp, Richard R; Shirts, Brian; Spinner, Nancy B; Tabor, Holly K; Tarczy-Hornoch, Peter; Veenstra, David L; Wagle, Nikhil; Weck, Karen; Wilfond, Benjamin S; Wilhelmsen, Kirk; Wolf, Susan M; Wynn, Julia; Yu, Joon-Ho

    2016-06-01

    Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine.

  11. A Social Approach to Decision-Making Capacity: Exploratory Research with People with Experience of Mental Health Treatment

    Science.gov (United States)

    McDaid, Shari; Delaney, Sarah

    2011-01-01

    This paper reports on exploratory, qualitative research conducted with eight people with experience of mental health treatment about their understanding of decision-making capacity. While acknowledging that there are times when mental or emotional distress can interfere with the capacity to make decisions, participants described how their capacity…

  12. Using exploratory factor analysis in personality research: Best-practice recommendations

    Directory of Open Access Journals (Sweden)

    Sumaya Laher

    2010-03-01

    Full Text Available Orientation: Exploratory factor analysis is the method of choice with objective personality instruments, particularly to establish the construct validity and construct equivalence of trait-based instruments.Research purpose: This article presents more objective methods to determine the number of factors, most notably parallel analysis and Velicer’s minimum average partial (MAP. The benefits of rotation are also discussed. The article argues for more consistent use of Procrustes rotation and congruence coefficients in factor analytic studies.Motivation for the study: Exploratory factor analysis is often criticised for not being rigorous and objective enough in terms of the methods used to determine the number of factors, the rotations to be used and ultimately the validity of the factor structure.Research design, approach and method: The article adopts a theoretical stance to discuss the best-practice recommendations for factor analytic research in the field of psychology. Following this, an example located within personality assessment and using the NEO-PI-R specifically is presented. A total of 425 students at the University of the Witwatersrand completed the NEO-PI-R. These responses were subjected to a principal components analysis using varimax rotation. The rotated solution was subjected to a Procrustes rotation with Costa and McCrae’s (1992 matrix as the target matrix. Congruence coefficients were also computed.Main findings: The example indicates the use of the methods recommended in the article and demonstrates an objective way of determining the number of factors. It also provides an example of Procrustes rotation with coefficients of agreement as an indication of how factor analytic results may be presented more rigorously in local research.Practical/managerial implications: It is hoped that the recommendations in this article will have best-practice implications for both researchers and practitioners in the field who employ factor

  13. Exploratory Technology Research Program for Electrochemical Energy Storage - Annual Report for 1998

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. (editor)

    1999-06-01

    The US Department of Energy's (DOE) Office of Advanced Automotive Technologies conducts research and development on advanced rechargeable batteries for application in electric vehicles (EVs) and hybrid systems. Efforts are focused on advanced batteries that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. DOE battery R and D supports two major programs: the US Advanced Battery Consortium (USABC), which develops advanced batteries for EVS, and the Partnership for a New Generation of Vehicles (PNGV), which seeks to develop passenger vehicles with a fuel economy equivalent to 80 mpg of gasoline. This report describes the activities of the Exploratory Technology Research (ETR) Program, managed by the Lawrence Berkeley National Laboratory (LBNL). The role of the ETR Program is to perform supporting research on the advanced battery systems under development by the USABC and PNGV Programs, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or other Government agencies for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1998. This is a continuing program, and reports for prior years have been published; they are listed at the end of this Program Summary.

  14. Basic statistical tools in research and data analysis

    Science.gov (United States)

    Ali, Zulfiqar; Bhaskar, S Bala

    2016-01-01

    Statistical methods involved in carrying out a study include planning, designing, collecting data, analysing, drawing meaningful interpretation and reporting of the research findings. The statistical analysis gives meaning to the meaningless numbers, thereby breathing life into a lifeless data. The results and inferences are precise only if proper statistical tests are used. This article will try to acquaint the reader with the basic research tools that are utilised while conducting various studies. The article covers a brief outline of the variables, an understanding of quantitative and qualitative variables and the measures of central tendency. An idea of the sample size estimation, power analysis and the statistical errors is given. Finally, there is a summary of parametric and non-parametric tests used for data analysis.

  15. Basic to industrial research on neutron platform in Japan

    Indian Academy of Sciences (India)

    Yasuhiko Fujii

    2008-10-01

    The co-location of reactor- and accelerator-based neutron sources offers a great opportunity for complementary use of steady and pulsed neutron beams in a wide variety of neutron science and technology areas ranging from basic research to industrial applications. In Japan, such a balance of two kinds of neutron sources has a long tradition and now we are entering into a new era with the commissioning of the world’s most intense pulsed neutron beams at JSNS/J-PARC plus the existing JRR-3 reactor both co-located within 1 km of each other in Tokai. The joint operation of these neutron facilities in close proximity under a program called `neutron platform', will allow neutron beam access not only to professional users, familiar with both pulsed and steady state techniques but also to first-time academics and industrial researchers to neutron scattering.

  16. Basic statistical tools in research and data analysis

    Directory of Open Access Journals (Sweden)

    Zulfiqar Ali

    2016-01-01

    Full Text Available Statistical methods involved in carrying out a study include planning, designing, collecting data, analysing, drawing meaningful interpretation and reporting of the research findings. The statistical analysis gives meaning to the meaningless numbers, thereby breathing life into a lifeless data. The results and inferences are precise only if proper statistical tests are used. This article will try to acquaint the reader with the basic research tools that are utilised while conducting various studies. The article covers a brief outline of the variables, an understanding of quantitative and qualitative variables and the measures of central tendency. An idea of the sample size estimation, power analysis and the statistical errors is given. Finally, there is a summary of parametric and non-parametric tests used for data analysis.

  17. Assessment of basic research needs for greenhouse gas control technologies

    Energy Technology Data Exchange (ETDEWEB)

    Benson, S.M.; Chandler, W.; Edmonds, J.; Houghton, J.; Levine, M.; Bates, L.; Chum, H.; Dooley, J.; Grether, D.; Logan, J.; Wiltsee, G.; Wright, L.

    1998-09-01

    This paper is an outgrowth of an effort undertaken by the Department of Energy's Office of Energy Research to assess the fundamental research needs to support a national program in carbon management. Five topics were identified as areas where carbon management strategies and technologies might be developed: (1) capture of carbon dioxide, decarbonization strategies, and carbon dioxide disposal and utilization; (2) hydrogen development and fuel cells; (3) enhancement of the natural carbon cycle; (4) biomass production and utilization; and (5) improvement of the efficiency of energy production, conversion, and utilization. Within each of these general areas, experts came together to identify targets of opportunity for fundamental research likely to lead to the development of mid- to long-term solutions for stabilizing or decreasing carbon dioxide and other greenhouse gases in the atmosphere. Basic research to support the options outlined above are far reaching-from understanding natural global processes such as the ocean and terrestrial carbon cycles to development of new materials and concepts for chemical separation. Examples of fundamental research needs are described in this paper.

  18. Controlling Subsurface Fractures and Fluid Flow: A Basic Research Agenda

    Energy Technology Data Exchange (ETDEWEB)

    Pyrak-Nolte, Laura J [Purdue Univ., West Lafayette, IN (United States); DePaolo, Donald J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Pietraß, Tanja [USDOE Office of Science, Washington, DC (United States)

    2015-05-22

    From beneath the surface of the earth, we currently obtain about 80-percent of the energy our nation consumes each year. In the future we have the potential to generate billions of watts of electrical power from clean, green, geothermal energy sources. Our planet’s subsurface can also serve as a reservoir for storing energy produced from intermittent sources such as wind and solar, and it could provide safe, long-term storage of excess carbon dioxide, energy waste products and other hazardous materials. However, it is impossible to underestimate the complexities of the subsurface world. These complexities challenge our ability to acquire the scientific knowledge needed for the efficient and safe exploitation of its resources. To more effectively harness subsurface resources while mitigating the impacts of developing and using these resources, the U.S. Department of Energy established SubTER – the Subsurface Technology and Engineering RD&D Crosscut team. This DOE multi-office team engaged scientists and engineers from the national laboratories to assess and make recommendations for improving energy-related subsurface engineering. The SubTER team produced a plan with the overall objective of “adaptive control of subsurface fractures and fluid flow.”This plan revolved around four core technological pillars—Intelligent Wellbore Systems that sustain the integrity of the wellbore environment; Subsurface Stress and Induced Seismicity programs that guide and optimize sustainable energy strategies while reducing the risks associated with subsurface injections; Permeability Manipulation studies that improve methods of enhancing, impeding and eliminating fluid flow; and New Subsurface Signals that transform our ability to see into and characterize subsurface systems. The SubTER team developed an extensive R&D plan for advancing technologies within these four core pillars and also identified several areas where new technologies would require additional basic research

  19. Measuring Basic Needs Satisfaction: Evaluating Previous Research and Conducting New Psychometric Evaluations of the Basic Needs Satisfaction in General Scale

    Science.gov (United States)

    Johnston, Mary M.; Finney, Sara J.

    2010-01-01

    Self-Determination Theory specifies the existence of three basic psychological needs: autonomy, competence, and relatedness. The current set of studies (a) provides a narrative review of past research on the Basic Needs Satisfaction in General Scale, (b) examines its dimensionality which has been assumed but not empirically studied, and (c)…

  20. Ethical Responsibility of Neuromarketing Companies in Harnessing the Market Research – a Global Exploratory Approach

    Directory of Open Access Journals (Sweden)

    Nicolae Al. Pop

    2014-02-01

    Full Text Available A key challenge in the 21st century is identifying how to satisfy consumers’ needs in the best manner possible, whilst ensuring companies’ financial profitability. Scientists play a major role in achieving this goal, as research methods, techniques and tools have continuously evolved. In the last two decades, the development of these instruments has seen an important boost, as neuromarketing methods and techniques added depth and accuracy to traditional studies. The main aim of this paper is to highlight the role and importance of neuromarketing research techniques in the evolution of neurosciences and to explain how these techniques are used in market research. One of the most important challenges for companies who offer neuromarketing services is to stick to ethical principles when performing the investigations. This is an obligation they have both towards the beneficiaries – the companies providing products or services – and towards their consumers as well. This challenge has always been a subject of dispute between the advocates and critics of neuromarketing. Thus, this paper deals with this and other controversial topics. It starts with analysing a traditional persuasion model that has inherently been influenced by the neuromarketing research features. Then, it addresses the positive and negative aspects that subjects might have to face throughout neuromarketing studies, always bearing in mind the current Ethical Code of Conduct issued by the Neuromarketing Science and Business Association (NMSBA. An exploratory online research helped the authors test several hypotheses on ethical issues that neuromarketing companies have to handle. The research was performed on 67 neuromarketing companies from around the world that are members of the NMSBA. The findings are relevant both to researchers and neuromarketing companies, even the Romanian ones, who can use them used as insights.

  1. Undergraduate Student Researchers, Preferred Learning Styles, and Basic Science Research: A Winning Combination

    Science.gov (United States)

    Woeste, Lori A.; Barham, Beverly J.

    2007-01-01

    In basic science research, student researchers are often challenged with not only the technical portion of the research design but also the team dynamic. Understanding how a student prefers to learn can provide an advantage for mentors to better meet these challenges. In this article, the authors describe the experience of working with student…

  2. The Romanian Ombudsman and It's Interraction with the Courts- An Exploratory Research

    Directory of Open Access Journals (Sweden)

    Dacian DRAGOŞ

    2010-10-01

    Full Text Available The article focuses on the institution of the Ombudsman and its relations with other institutions/ powers of the state. The least explored interaction, at least in the Romanian literature, is the interaction between the Ombudsman and the courts (both the Constitutional Court and the ordinary ones, in the context of the need for Ombudsman institutions to develop the so called ‘Ombudsnorms’ of good administration. There are no empirical studies trying to explore this interaction and how it actually works in practice. The first part of the article offers an analysis of the existing literature on the interaction between the Ombudsman institution and the courts in various legal systems. The second part of the article consists of an exploratory empirical research of the interaction between the Romanian Ombudsman and the courts. The methodology of the research is qualitative – analysis of the Ombudsman’s annual reports and structured interviews with judges and the representative of the Romanian Ombudsman institution. The main conclusion of the study is that until now the interaction is rather limited and that there seems to be no ‘desire’ on behalf of both the courts and the Ombudsman to explore the possibilities for more cooperation/interaction, the main reason given being the independence of justice.

  3. Why Companies Do Not Renew Their EMAS Registration? An Exploratory Research

    Directory of Open Access Journals (Sweden)

    Michele Preziosi

    2016-02-01

    Full Text Available The Eco-Management and Audit Scheme (EMAS is the official Environmental Management System (EMS issued by the European Union (EU. Italy is the country where EMAS is most widespread, accounting for over 1000 registered organizations. Since entry into the force of the Regulation in 1997, the number of registrations has constantly grown until 2008, when the figures started to drop. The phenomena are due to both the decrease of the annual registration rate and the lack of renewals. According to the Italian Institute for Environmental Protection and Research (ISPRA, in recent years, an increasing number of organizations decided to withdraw from EMAS registration. The purpose of this paper is to analyze the reasons of this negative trend. The first step consisted of a literature review concerning the main barriers, difficulties, and costs incurred by EMAS-registered organizations. Subsequently, this information was integrated with data about the evolution of EMAS registrations and the results of a previous survey, which involved the entire population of registered firms. The present exploratory research highlighted economic and operational domains concerning the cancellation trends that deserve a deeper investigation, which will be conducted through a questionnaire addressed to Italian firms that did not renew the registration in the last lustrum. The intended output will allow us to identify stakeholders’ priority intervention areas in order to suggest an operative strategy to reduce EMAS cancellation rates, addressed to Member States (MS Competent Bodies.

  4. Religiosity As An Antecedent Of Attitude Towards Green Products: An Exploratory Research On Young Malaysian Consumers

    Directory of Open Access Journals (Sweden)

    Lau Teck Chai

    2009-06-01

    Full Text Available Religion has long been acknowledged as an important social force that influences human behavior but yet in the secular society its influence on consumer behavior appears to be underestimated. Of the sporadic research conducted, findings indicated that religion can be a significant factor in relation to consumption patterns, innovativeness, media usage, family decision-making, purchase risk aversion and selected store patronage behavior. The current research is exploratory in nature and attempts to investigate the influence of religiosity on attitudes towards green products especially among young Malaysian consumers. Religiosity, the independent variable, was measured by the intrinsic/ extrinsic religious orientation scale adopted from Allport and Ross (1967. The dependent variable was derived from a study on attitudes towards green product (Mostafa, 2007. The questionnaires were distributed to students in a large private university located in Klang Valley, Malaysia. Reliability analysis and multiple linear regressions were conducted. The results from the multiple linear regression analysis indicate that intrinsic religiosity has a significant relationship on consumer’s attitude towards green product. However, in the case of extrinsic religiosity, there is no significant relationship on consumer’s attitude towards green product.

  5. Basic research on human reliability in nuclear power plants

    International Nuclear Information System (INIS)

    Human reliability in nuclear power plants is one of key factors in nuclear safety and economic operation. According to cognitive science, behaviour theory and ergonomic and on the bases of human cognitive behaviour characteristics, performance shaping factors, human error mechanisms and organization management, the project systematically studied the human reliability in nuclear power plant systems, established the basic theory and methods for analyzing human factor accidents and suggested feasible approaches and countermeasures for precaution against human factor accidents and improving human reliability. The achievement has been applied in operation departments, management departments and scientific research institutions of nuclear power, and has produced guiding significance and practical value to design, operation and management in nuclear power plants. (11 refs.)

  6. Research on basic characteristics of complex system brittleness

    Institute of Scientific and Technical Information of China (English)

    JIN Hong-zhang; GUO Jian; WEI Qi; LIN De-ming; LI Qi

    2004-01-01

    Tbe goal of this paper is to research one new characteristic of complex system. Brittleness, which is one new characteritic of complex system, is presented in this paper. The linguistic and qualitative descriptions of complex system are also given in this paper.Otherwise, the qualitative description of complex system is presented at first. On the basis of analyzing the existing brittleness problems, linguistic description and mathematic description of brittleness are given as well. Three kinds of phenomena to judge brittleness of complex system are also given, based on catastrophe theory. Basic characteristics of brittleness are given on the basis of its mathematic description. Two critical point sets are defined by using catastrophe theory. The definition of brittleness and its related theory can serve the control of complex system, and provide theoretical basis for the design and control of complex system.

  7. Exploratory Technology Research Program for electrochemical energy storage: Annual report for 1993

    International Nuclear Information System (INIS)

    The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R ampersand D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EVs). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R ampersand D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EVs. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993

  8. Exploratory Technology Research Program for electrochemical energy storage: Annual report for 1993

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. [ed.

    1994-09-01

    The U.S. Department of Energy`s Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EVs). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EVs. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

  9. Exploratory Technology Research Program for electrochemical energy storage. Annual report for 1991

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. [ed.

    1992-06-01

    The US Department of Energy`s Office of Propulsion Systems provides support for an electrochemical energy storage program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles. The program centers on advanced systems that offer the potential for high performance and low life-cycle costs. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems Development (EVABS) Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratory, and the Lawrence Berkeley Laboratory is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on several candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the US automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EVs. The role of the ETR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scaleup. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1991.

  10. Polymer materials basic research needs for energy applications

    Energy Technology Data Exchange (ETDEWEB)

    Macknight, W.J.; Baer, E.; Nelson, R.D. (eds.)

    1978-08-01

    The larger field covered in the workshop consists of (1) synthesis and characterization, (2) physical chemistry, (3) physics, and (4) engineering. Polymeric materials are properly regarded as new materials in their own right, not as replacements for existing materials. As such they need to be studied to understand the properties which are unique to them by virtue of their particular molecular structures. Technological applications will rationally follow from such studies. It is the objective of this report to point out basic research needs in polymer materials related to energy. The development of sophisticated instrumentation makes the task of molecular characterization possible on a level hitherto unattainable. Many of these instruments because of their size and complexity must of necessity be located at the DOE National Laboratories. The importance of personnel trained in the polymer field located at these facilities is emphasized. In the past there has been relatively little concerted polymer research within the energy community. This report attempts to describe the present situation and point out some needs and future research directions. (GHT)

  11. Science Serving the Nation: The Impact of Basic Research

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-01-01

    Impacts: The BES program supports basic research that underpins a broad range of energy technologies. Research in materials sciences and engineering leads to the development of materials that improve the efficiency, economy, environmental acceptability, and safety of energy generation, conversion, transmission, storage, and use. For example, advances in superconductivity have been introduced commercially in a number of demonstration projects around the country. Improvements in alloy design for high temperature applications are used in commercial furnaces and in green technologies such as lead-free solder. Research in chemistry has led to advances such as efficient combustion systems with reduced emissions of pollutants; new solar photoconversion processes; improved catalysts for the production of fuels and chemicals; and better separations and analytical methods for applications in energy processes, environmental remediation, and waste management. Research in geosciences results in advanced monitoring and measurement techniques for reservoir definition and an understanding of the fluid dynamics of complex fluids through porous and fractured subsurface rock. Research in the molecular and biochemical nature of photosynthesis aids the development of solar photo-energy conversion. The BES program also plays a major role in enabling the nanoscale revolution. The importance of nanoscience to future energy technologies is clearly reflected by the fact that all of the elementary steps of energy conversion (e.g., charge transfer, molecular rearrangement, and chemical reactions) take place on the nanoscale. The development of new nanoscale materials, as well as the methods to characterize, manipulate, and assemble them, create an entirely new paradigm for developing new and revolutionary energy technologies.

  12. Controlling Subsurface Fractures and Fluid Flow: A Basic Research Agenda

    Energy Technology Data Exchange (ETDEWEB)

    Pyrak-Nolte, Laura J [Purdue Univ., West Lafayette, IN (United States); DePaolo, Donald J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Pietraß, Tanja [USDOE Office of Science, Washington, DC (United States)

    2015-05-22

    From beneath the surface of the earth, we currently obtain about 80-percent of the energy our nation consumes each year. In the future we have the potential to generate billions of watts of electrical power from clean, green, geothermal energy sources. Our planet’s subsurface can also serve as a reservoir for storing energy produced from intermittent sources such as wind and solar, and it could provide safe, long-term storage of excess carbon dioxide, energy waste products and other hazardous materials. However, it is impossible to underestimate the complexities of the subsurface world. These complexities challenge our ability to acquire the scientific knowledge needed for the efficient and safe exploitation of its resources. To more effectively harness subsurface resources while mitigating the impacts of developing and using these resources, the U.S. Department of Energy established SubTER – the Subsurface Technology and Engineering RD&D Crosscut team. This DOE multi-office team engaged scientists and engineers from the national laboratories to assess and make recommendations for improving energy-related subsurface engineering. The SubTER team produced a plan with the overall objective of “adaptive control of subsurface fractures and fluid flow.”This plan revolved around four core technological pillars—Intelligent Wellbore Systems that sustain the integrity of the wellbore environment; Subsurface Stress and Induced Seismicity programs that guide and optimize sustainable energy strategies while reducing the risks associated with subsurface injections; Permeability Manipulation studies that improve methods of enhancing, impeding and eliminating fluid flow; and New Subsurface Signals that transform our ability to see into and characterize subsurface systems. The SubTER team developed an extensive R&D plan for advancing technologies within these four core pillars and also identified several areas where new technologies would require additional basic research

  13. Exploratory technology research program for electrochemical energy storage, annual report for 1997

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, K. [ed.

    1998-06-01

    The US Department of Energy`s (DOE) Office of Transportation Technologies provides support for an Electrochemical Energy Storage Program, that includes research and development on advanced rechargeable batteries. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EVs) and hybrid systems. The program centers on advanced electrochemical systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electric Vehicle Technology Program is divided into two project areas: the US Advanced Battery Consortium (USABC) and Advanced Battery R and D which includes the Exploratory Technology Research (ETR) Program managed by the Lawrence Berkeley National Laboratory (LBNL). The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or other Government agencies for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1997. This is a continuing program, and reports for prior years have been published; they are listed at the end of this Executive Summary. The general R and D areas addressed by the program include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, and establishment of engineering principles applicable to electrochemical energy storage. Major emphasis is given to applied research which will lead to superior performance and lower life-cycle costs.

  14. Exploratory technology research program for electrochemical energy storage. Annual report for 1995

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, Kim [ed.

    1996-06-01

    The US DOE Office of Transportation Technologies provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV`s)and hybrid systems. The program centers on advanced electrochemical systems that offer the potential for high performance and low life- cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electric Vehicle Technology Program is divided into two project areas: the US Advanced Battery Consortium (USABC) and Advanced battery R&D which includes the Exploratory Technology Research (ETR) program managed by the Lawrence Berkeley National Laboratory. The role of the ETR program is to perform supporting research on the advanced battery systems under development by the USABC and the Sandia Laboratories (SNL) Electric Vehicle Advanced Battery Systems (EVABS) program, and to evaluate new systems with potentially superior performance, durability and/of cost characteristics. The specific goal of the ETR program is to identify the most promising electrochemical technologies and development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR program in CY 1995. This is a continuing program, and reports for prior years have been published; they are listed in this report.The general R&D areas addressed by the program include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, establishment of engineering principles applicable to electrochemical energy storage and conversion, and the development of fuel cell technology for transportation applications.

  15. Basic Research Needs for Carbon Capture: Beyond 2020

    Energy Technology Data Exchange (ETDEWEB)

    Alivisatos, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Buchanan, Michelle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2010-03-04

    This report is based on a SC/FE workshop on Carbon Capture: Beyond 2020, held March 4–5, 2010, to assess the basic research needed to address the current technical bottlenecks in carbon capture processes and to identify key research priority directions that will provide the foundations for future carbon capture technologies. The problem of thermodynamically efficient and scalable carbon capture stands as one of the greatest challenges for modern energy researchers. The vast majority of US and global energy use derives from fossil fuels, the combustion of which results in the emission of carbon dioxide into the atmosphere. These anthropogenic emissions are now altering the climate. Although many alternatives to combustion are being considered, the fact is that combustion will remain a principal component of the global energy system for decades to come. Today’s carbon capture technologies are expensive and cumbersome and energy intensive. If scientists could develop practical and cost-effective methods to capture carbon, those methods would at once alter the future of the largest industry in the world and provide a technical solution to one of the most vexing problems facing humanity. The carbon capture problem is a true grand challenge for today’s scientists. Postcombustion CO2 capture requires major new developments in disciplines spanning fundamental theoretical and experimental physical chemistry, materials design and synthesis, and chemical engineering. To start with, the CO2 molecule itself is thermodynamically stable and binding to it requires a distortion of the molecule away from its linear and symmetric arrangement. This binding of the gas molecule cannot be too strong, however; the sheer quantity of CO2 that must be captured ultimately dictates that the capture medium must be recycled over and over. Hence the CO2 once bound, must be released with relatively little energy input. Further, the CO2 must be rapidly and selectively pulled out of a mixture

  16. Social and behavioral research in genomic sequencing: approaches from the Clinical Sequencing Exploratory Research Consortium Outcomes and Measures Working Group.

    Science.gov (United States)

    Gray, Stacy W; Martins, Yolanda; Feuerman, Lindsay Z; Bernhardt, Barbara A; Biesecker, Barbara B; Christensen, Kurt D; Joffe, Steven; Rini, Christine; Veenstra, David; McGuire, Amy L

    2014-10-01

    The routine use of genomic sequencing in clinical medicine has the potential to dramatically alter patient care and medical outcomes. To fully understand the psychosocial and behavioral impact of sequencing integration into clinical practice, it is imperative that we identify the factors that influence sequencing-related decision making and patient outcomes. In an effort to develop a collaborative and conceptually grounded approach to studying sequencing adoption, members of the National Human Genome Research Institute's Clinical Sequencing Exploratory Research Consortium formed the Outcomes and Measures Working Group. Here we highlight the priority areas of investigation and psychosocial and behavioral outcomes identified by the Working Group. We also review some of the anticipated challenges to measurement in social and behavioral research related to genomic sequencing; opportunities for instrument development; and the importance of qualitative, quantitative, and mixed-method approaches. This work represents the early, shared efforts of multiple research teams as we strive to understand individuals' experiences with genomic sequencing. The resulting body of knowledge will guide recommendations for the optimal use of sequencing in clinical practice.

  17. Basic Requirements for Systems Software Research and Development

    Science.gov (United States)

    Kuszmaul, Chris; Nitzberg, Bill

    1996-01-01

    Our success over the past ten years evaluating and developing advanced computing technologies has been due to a simple research and development (R/D) model. Our model has three phases: (a) evaluating the state-of-the-art, (b) identifying problems and creating innovations, and (c) developing solutions, improving the state- of-the-art. This cycle has four basic requirements: a large production testbed with real users, a diverse collection of state-of-the-art hardware, facilities for evalua- tion of emerging technologies and development of innovations, and control over system management on these testbeds. Future research will be irrelevant and future products will not work if any of these requirements is eliminated. In order to retain our effectiveness, the numerical aerospace simulator (NAS) must replace out-of-date production testbeds in as timely a fashion as possible, and cannot afford to ignore innovative designs such as new distributed shared memory machines, clustered commodity-based computers, and multi-threaded architectures.

  18. Basic researches for advancement of man-machine systems

    International Nuclear Information System (INIS)

    The historical development of plant instrumentation and control system accompanying the introduction of automation is shown by the example of nuclear power plants. It is explained, and the change in the role of operators in the man-machine system is mentioned. Human errors are the serious problem in various fields, and automation resolves it. But complex systems also caused various disasters due to the relation of men and machines. The problem of human factors in high risk system automation is considered as the heightening of reliability and the reduction of burden on workers by decreasing human participation, and the increase of the risk of large accidents due to the lowering of reliability of human elements and the strengthening of the training of workers. Human model and the framework of human error analysis, the development of the system for man-machine system design and information analysis and evaluation, the significance of physiological index measurement and the perspective of the application, the analysis of the behavior of subjects in the abnormality diagnosis experiment using a plant simulator, and the development to the research on mutual adaptation interface are discussed. In this paper, the problem of human factors in system safety, that technical advancement brings about is examined, and the basic research on the advancement of man-machine systems by the author is reported. (K.I.)

  19. Basic Research Needs for Carbon Capture: Beyond 2020

    Energy Technology Data Exchange (ETDEWEB)

    Alivisatos, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Buchanan, Michelle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2010-03-04

    This report is based on a SC/FE workshop on Carbon Capture: Beyond 2020, held March 4–5, 2010, to assess the basic research needed to address the current technical bottlenecks in carbon capture processes and to identify key research priority directions that will provide the foundations for future carbon capture technologies. The problem of thermodynamically efficient and scalable carbon capture stands as one of the greatest challenges for modern energy researchers. The vast majority of US and global energy use derives from fossil fuels, the combustion of which results in the emission of carbon dioxide into the atmosphere. These anthropogenic emissions are now altering the climate. Although many alternatives to combustion are being considered, the fact is that combustion will remain a principal component of the global energy system for decades to come. Today’s carbon capture technologies are expensive and cumbersome and energy intensive. If scientists could develop practical and cost-effective methods to capture carbon, those methods would at once alter the future of the largest industry in the world and provide a technical solution to one of the most vexing problems facing humanity. The carbon capture problem is a true grand challenge for today’s scientists. Postcombustion CO2 capture requires major new developments in disciplines spanning fundamental theoretical and experimental physical chemistry, materials design and synthesis, and chemical engineering. To start with, the CO2 molecule itself is thermodynamically stable and binding to it requires a distortion of the molecule away from its linear and symmetric arrangement. This binding of the gas molecule cannot be too strong, however; the sheer quantity of CO2 that must be captured ultimately dictates that the capture medium must be recycled over and over. Hence the CO2 once bound, must be released with relatively little energy input. Further, the CO2 must be rapidly and selectively pulled out of a mixture

  20. Exploratory Research On Students` Opinions Regarding The Features Of The Educational Process In A Knowledge-Based Economy

    OpenAIRE

    Sorin-George Toma

    2011-01-01

    Knowledge has always been central to social and human life. In the past decades, new forms of knowledge and technologies have emerged constantly in the knowledge-based economy, a new stage of the capitalist economic system. The aims of our paper are to render in brief the theoretical approaches related to the knowledge-based economy and to highlight the results of an exploratory research regarding students’ opinions on the main features of the educational process of a Marketing academic speci...

  1. AN EXPLORATORY RESEARCH OVER THE CHINESE PRODUCTS ON THE ROMANIAN MARKET

    Directory of Open Access Journals (Sweden)

    Aldea Roxana

    2012-07-01

    Full Text Available In this paper we studied the influence on the Asian products over the consumer decision making. We observed that because of the economic crisis most of the people are buying products made in China, although they now that the quality and the price are lower. The factors that change the habits and the consumer behavior decision making are: the lower wage, the small number of work places and the prices of the products. Regarding the low price of Chinese products quality, some times arouses suspicions. Romania is a parts of the European Union and on the market there are various products made in European countries but also products made in China. People with low wages from the last step of social classes are prone to buy lower prices products. Other consumers on the contrary became more sensitive and they prefer to pay more than to buy products made in China. The quality prevails over the price and sometimes over the quantity although the money to spend are dwindled. The crisis affected consumer behavior, consumers have become more attentive to the country of origin and the disposable income for shopping. In order to validate some of the ideas the authors undertook a quantitative online research. The research had as purpose to identify the main influences of the decision making when the consumer buys Chinese products. The chosen investigation was the selective survey, the research technique was the exploratory interrogation and the research instrument – structured in online questionnaire. After research we found that the economic crisis caused consumer behavior change as a result of diminishing the income buyers, the consumer is placed in a position to buy products of questionable quality at low prices, mostly from China. Lower purchase price often makes Chinese goods represent an attractive option for consumers. On the other hand, the quality of Chinese products has proven to not comply with the quality expectations of the consumers, based on

  2. Muscle wasting: an overview of recent developments in basic research.

    Science.gov (United States)

    Palus, Sandra; von Haehling, Stephan; Springer, Jochen

    2014-09-01

    The syndrome of cachexia, i.e., involuntary weight loss in patients with underlying diseases, sarcopenia, i.e., loss of muscle mass due to aging, and general muscle atrophy from disuse and/or prolonged bed rest have received more attention over the last decades. All lead to a higher morbidity and mortality in patients, and therefore, they represent a major socio-economic burden for the society today. This mini-review looks at recent developments in basic research that are relevant to the loss of skeletal muscle. It aims to cover the most significant publication of last 3 years on the causes and effects of muscle wasting, new targets for therapy development, and potential biomarkers for assessing skeletal muscle mass. The targets include the following: (1) E-3 ligases TRIM32, SOCS1, and SOCS3 by involving the elongin BC ubiquitin-ligase, Cbl-b, culling 7, Fbxo40, MG53 (TRIM72), and the mitochondrial Mul1; (2) the kinase MST1; and (3) the G-protein Gαi2. D(3)-creatine has the potential to be used as a novel biomarker that allows to monitor actual change in skeletal muscle mass over time. In conclusion, significant development efforts are being made by academic groups as well as numerous pharmaceutical companies to identify new target and biomarker muscles, as muscle wasting represents a great medical need, but no therapies have been approved in the last decades. PMID:25163459

  3. Forest Bio-disaster Status and its Basic Research in China

    Institute of Scientific and Technical Information of China (English)

    Gu Ruisheng; Yu Zhenliang; Du Shengming

    2005-01-01

    This review outlines the characteristics and developmental trends of forest bio-disasters ( including disease, insect and rodent pests ) of recent years in China, summarizes the achievements of the basic researches supported by the National Natural Science Foundation of China, defines the main drawbacks, and proposes some important issues to be highlighted in the basic research in the future in order to integrate research resources, concentrate research objectives and toaccelerate the development of forest bio-disaster basic research in China.

  4. Preliminary Results From NASA's Space Solar Power Exploratory Research and Technology Program

    Science.gov (United States)

    Howell, Joe T.; Mankins, John C.

    2000-01-01

    Large solar power satellite (SPS) systems that might provide base load power into terrestrial markets were examined extensively in the 1970s by the US Department of Energy (DOE) and the National Aeronautics and Space Administration (NASA). Following a hiatus of about 15 years, the subject of space solar power (SSP) was reexamined by NASA from 1995-1997 in the "fresh look" study, and during 1998 in an SSP "concept definition study". As a result of these efforts, during 1999-2000, NASA has been conducting the SSP Exploratory Research and Technology (SERT) program. The goal of the SERT activity has been to conduct preliminary strategic technology research and development to enable large, multi-megawatt SSP systems and wireless power transmission (WPT) for government missions and commercial markets (in-space and terrestrial). In pursuing that goal, the SERT: (1) refined and modeled systems approaches for the utilization of SSP concepts and technologies, ranging from the near-term (e.g., for space science, exploration and commercial space applications) to the far-term (e.g., SSP for terrestrial markets), including systems concepts, architectures, technology, infrastructure (e.g. transportation), and economics; (2) conducted technology research, development and demonstration activities to produce "proof-of-concept" validation of critical SSP elements for both nearer and farther-term applications; and (3) engendered the beginnings of partnerships (nationally and internationally) that could be expanded, as appropriate, to pursue later SSP technology and applications. Through these efforts, the SERT should allow better informed future decisions regarding further SSP and related technology research and development investments by both NASA and prospective partners, and guide further definition of technology roadmaps - including performance objectives, resources and schedules, as well as "multi-purpose" applications (e.g., commerce, science, and government). This paper

  5. Building Basic Skills: Results from Vocational Education. Research & Development Series No. 237.

    Science.gov (United States)

    Lotto, Linda S.

    A study examined current research on the proficiency of vocational students in basic skill areas and explored current practices for improving the basic skills of vocational students at the secondary and postsecondary levels. Based on current research, vocational students, on an average, seemed to be less proficient in basic skills than were their…

  6. Health researchers in Alberta: an exploratory comparison of defining characteristics and knowledge translation activities

    Directory of Open Access Journals (Sweden)

    Birdsell Judy M

    2007-01-01

    Full Text Available Abstract Background Canadian funding agencies are no longer content to support research that solely advances scientific knowledge, and key directives are now in place to promote research transfer to policy- and decision-makers. Therefore, it is necessary to improve our understanding of how researchers are trained and supported to facilitate knowledge translation activities. In this study, we investigated differences in health researcher characteristics and knowledge translation activities. Methods Our sample consisted of 240 health researchers from three Alberta universities. Respondents were classified by research domain [basic (n = 72 or applied (n = 168] and faculty [medical school (n = 128 or other health science (n = 112]. We examined our findings using Mode I and Mode II archetypes of knowledge production, which allowed us to consider the scholarly and social contexts of knowledge production and translation. Results Differences among health researcher professional characteristics were not statistically significant. There was a significant gender difference in the applied researcher faculty group, which was predominantly female (p p p = .01; Mode II, p p = .025 and number of publications (medical school > other faculties; p = .004. There was an interaction effect for research domain and faculty group for number of publications (p = .01, in that applied researchers in medical faculties published more than their peers in other faculty groups. Conclusion Our findings illustrate important differences between health researchers and provide beginning insights into their professional characteristics and engagement in Mode I and Mode II activities. A future study designed to examine these dimensions in greater detail, including potential covariates across more varied institutions, would yield richer insights and enable an examination of relative influences, needs and costs of each mode of activity.

  7. Clinical implications of basic research in hepatocellular carcinoma.

    Science.gov (United States)

    Dhanasekaran, Renumathy; Venkatesh, Sudhakar K; Torbenson, Michael S; Roberts, Lewis R

    2016-03-01

    A 58-year old Caucasian female has compensated hepatitis C related cirrhosis. Her surveillance ultrasound showed hypodense liver nodules and subsequent triple phase CT scan showed five tumor nodules with diameters ranging from 3-5cms involving both hepatic lobes. The nodules showed characteristic radiologic findings on the CT scan and she was diagnosed with hepatocellular carcinoma (HCC) based on non-invasive criteria. There was also associated right portal vein tumor thrombosis. Her functional capacity at diagnosis was slightly limited, but she was capable of performing all activities of daily living and self-care. Her laboratory tests at diagnosis were as follows: sodium 129mmol/L, potassium 3.6mmol/L, blood urea nitrogen 22mg/dL, creatinine 1.0mg/dL, albumin 2.9g/dl, bilirubin 1.8mg/dl, alanine aminotransferase 87U/L, aspartate aminotransferase 68U/L, alkaline phosphatase 139U/L, white blood cell 3.5x10(9)/L, hemoglobin 10.4, platelet count 73x10(9)/L, international normalized ratio 1.9 and alpha-fetoprotein 5200ng/ml. An upper endoscopy was negative for esophageal or gastric varices. Based on the tumor burden, presence of macrovascular invasion, ECOG performance status of 1 and Child-Pugh class A she was classified to have BCLC stage C HCC. She was started on sorafenib therapy at 400mg oral twice daily but unfortunately this had to be discontinued since she experienced severe diarrhea and skin rash. She now returns for follow-up and requests information on the available therapeutic options. This particular case scenario is not uncommon and does raise several clinically relevant questions: This review provides a comprehensive overview of the current state of HCC management and also examines the clinical implications of recent basic research in HCC. PMID:26450813

  8. Space Solar Power Exploratory Research and Technology (SERT) Technical Interchange Meeting 2 (SERT TIM 2)

    Science.gov (United States)

    Howell, Joe; Sanders, Clark W.

    2000-01-01

    The University of Alabama in Huntsville's (UAH) Propulsion Research Center hosted the Space Solar Power Exploratory Research & Technology (SERT) Technical Interchange Meeting TIM) 2 in Huntsville, Alabama December 7-10. 1999 with 126 people in attendance. The SERT program includes both competitively procured activities. which are being implemented through a portfolio of focused R&D investments--with the maximum leveraging of existing resources inside and outside NASA. and guided by these system studies. Axel Roth. Director of the Flight Projects Directorate NASA MSFC, welcomed the SERT TIM 2 participants and challenged them to develop the necessary technologies and demonstrations that will lead to Space Solar Power (SSP) International implementation. Joe Howell, NASA MSFC, reiterated the SERT TIM 2 objectives: 1) Refining and modeling systems approaches for the utilization of SSP concepts and technologies, ranging, from the near-term e.g. for space science, exploration and commercial space applications to the far-term (e. g. SSP for terrestrial markets), including systems concepts, technology, infrastructure (i.g., transportation), and economics. 2) Conducting technology research, development and demonstration activities to produce "proof- of-concept" validation of critical SSP elements for both the nearer and farther-term applications. 3) Initiating partnerships Nationality and Internationally that could be expanded, as appropriate, to pursue later SSP technology and applications (e.g., space science. colonization, etc.). Day one began with the NASA Centers presenting their SERT activities summary since SERT TIM 1 and wound up with a presentation by Masahiro Mori, NASDA titled "NASDA In-house Study for SSP". Demonstration for the Near-Term. Day two began with the SERT Systems Studies and Analysis reports resulting from NRA 8-23 followed by presentations of SERT Technology Demonstrations reports resulting from NRA 8-23. Day two closed with John Mankins presentation

  9. Exploratory Research on the Effect of Autonomous Learners to Team Learning within Healthcare Systems

    Science.gov (United States)

    Goodman, Patricia R.; Chalofsky, Neal

    2005-01-01

    How does individual learning impact team learning? Through an exploratory case study, data was collected from questionnaires, documentation review, observations, and interviews. Three themes emerged describing how an autonomous learner affected team learning. The results indicated that the autonomous learner influenced team learning through…

  10. Basic research and industrialization of CANDU advanced fuel

    International Nuclear Information System (INIS)

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  11. Basic research and industrialization of CANDU advanced fuel

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Suk Ho; Park, Joo Hwan; Jun, Ji Su [and others

    2000-04-01

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  12. Citation Analysis May Severely Underestimate the Impact of Clinical Research as Compared to Basic Research

    Science.gov (United States)

    van Eck, Nees Jan; Waltman, Ludo; van Raan, Anthony F. J.; Klautz, Robert J. M.; Peul, Wilco C.

    2013-01-01

    Background Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same medical field. Because of this, it is unclear to what extent citation-based bibliometric indicators allow for valid comparisons between research units active in different areas of medical research. Methodology A visualization methodology is introduced that reveals differences in citation practices between medical research areas. The methodology extracts terms from the titles and abstracts of a large collection of publications and uses these terms to visualize the structure of a medical field and to indicate how research areas within this field differ from each other in their average citation impact. Results Visualizations are provided for 32 medical fields, defined based on journal subject categories in the Web of Science database. The analysis focuses on three fields: Cardiac & cardiovascular systems, Clinical neurology, and Surgery. In each of these fields, there turn out to be large differences in citation practices between research areas. Low-impact research areas tend to focus on clinical intervention research, while high-impact research areas are often more oriented on basic and diagnostic research. Conclusions Popular bibliometric indicators, such as the h-index and the impact factor, do not correct for differences in citation practices between medical fields. These indicators therefore cannot be used to make accurate between-field comparisons. More sophisticated bibliometric indicators do correct for field differences but still fail to take into account within-field heterogeneity in citation practices. As a consequence, the citation impact of clinical intervention research may be substantially underestimated in comparison with basic and diagnostic research. PMID:23638064

  13. Citation analysis may severely underestimate the impact of clinical research as compared to basic research.

    Directory of Open Access Journals (Sweden)

    Nees Jan van Eck

    Full Text Available BACKGROUND: Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same medical field. Because of this, it is unclear to what extent citation-based bibliometric indicators allow for valid comparisons between research units active in different areas of medical research. METHODOLOGY: A visualization methodology is introduced that reveals differences in citation practices between medical research areas. The methodology extracts terms from the titles and abstracts of a large collection of publications and uses these terms to visualize the structure of a medical field and to indicate how research areas within this field differ from each other in their average citation impact. RESULTS: Visualizations are provided for 32 medical fields, defined based on journal subject categories in the Web of Science database. The analysis focuses on three fields: Cardiac & cardiovascular systems, Clinical neurology, and Surgery. In each of these fields, there turn out to be large differences in citation practices between research areas. Low-impact research areas tend to focus on clinical intervention research, while high-impact research areas are often more oriented on basic and diagnostic research. CONCLUSIONS: Popular bibliometric indicators, such as the h-index and the impact factor, do not correct for differences in citation practices between medical fields. These indicators therefore cannot be used to make accurate between-field comparisons. More sophisticated bibliometric indicators do correct for field differences but still fail to take into account within-field heterogeneity in citation practices. As a consequence, the citation impact of clinical intervention research may be substantially underestimated in comparison with basic and diagnostic research.

  14. Cluster: Drafting. Course: Basic Technical Drafting. Research Project.

    Science.gov (United States)

    Sanford - Lee County Schools, NC.

    The set of six units is designed for use with an instructor in basic technical drafting and is also keyed to other texts. Each unit contains several task packages specifying prerequisites, rationale for learning, objectives, learning activities to be supervised by the instructor, and learning practice. The units cover: pictorial drawing; screw…

  15. Science and Industry: Tracing the Flow of Basic Research through Manufacturing and Trade

    OpenAIRE

    Adams, James D.; Roger Clemmons

    2006-01-01

    This paper describes flows of basic research through the U.S. economy and explores their implications for scientific output at the industry and field level. The time period is the late 20th century. This paper differs from others in its use of measures of science rather than technology. Together its results provide a more complete picture of the structure of basic research flows than was previously available. Basic research flows are high within petrochemicals and drugs and within a second cl...

  16. Basic Research Needs for Advanced Nuclear Systems. Report of the Basic Energy Sciences Workshop on Basic Research Needs for Advanced Nuclear Energy Systems, July 31-August 3, 2006

    Energy Technology Data Exchange (ETDEWEB)

    Roberto, J.; Diaz de la Rubia, T.; Gibala, R.; Zinkle, S.; Miller, J.R.; Pimblott, S.; Burns, C.; Raymond, K.; Grimes, R.; Pasamehmetoglu, K.; Clark, S.; Ewing, R.; Wagner, A.; Yip, S.; Buchanan, M.; Crabtree, G.; Hemminger, J.; Poate, J.; Miller, J.C.; Edelstein, N.; Fitzsimmons, T.; Gruzalski, G.; Michaels, G.; Morss, L.; Peters, M.; Talamini, K.

    2006-10-01

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  17. Basic science research in pediatric radiology - how to empower the leading edge of our field.

    Science.gov (United States)

    Daldrup-Link, Heike E

    2014-08-01

    Basic science research aims to explore, understand and predict phenomena in the natural world. It spurs the discovery of fundamentally new principles and leads to new knowledge and new concepts. By comparison, applied research employs basic science knowledge toward practical applications. In the clinical realm, basic science research and applied research should be closely connected. Basic science discoveries can build the foundation for a broad range of practical applications and thereby bring major benefits to human health, education, environment and economy. This article explains how basic science research impacts our field, it describes examples of new research directions in pediatric imaging and it outlines current challenges that we need to overcome in order to enable the next groundbreaking discovery.

  18. An introduction to the partial least squares approach to structural equation modelling: a method for exploratory psychiatric research.

    Science.gov (United States)

    Riou, Julien; Guyon, Hervé; Falissard, Bruno

    2016-09-01

    In psychiatry and psychology, relationship patterns connecting disorders and risk factors are always complex and intricate. Advanced statistical methods have been developed to overcome this issue, the most common being structural equation modelling (SEM). The main approach to SEM (CB-SEM for covariance-based SEM) has been widely used by psychiatry and psychology researchers to test whether a comprehensive theoretical model is compatible with observed data. While the validity of this approach method has been demonstrated, its application is limited in some situations, such as early-stage exploratory studies using small sample sizes. The partial least squares approach to SEM (PLS-SEM) has risen in many scientific fields as an alternative method that is especially useful when sample size restricts the use of CB-SEM. In this article, we aim to provide a comprehensive introduction to PLS-SEM intended to CB-SEM users in psychiatric and psychological fields, with an illustration using data on suicidality among prisoners. Researchers in these fields could benefit from PLS-SEM, a promising exploratory technique well adapted to studies on infrequent diseases or specific population subsets. Copyright © 2015 John Wiley & Sons, Ltd.

  19. Stem cells: basic research on health, from ethics to panacea

    Directory of Open Access Journals (Sweden)

    Naara Luna

    2007-01-01

    Full Text Available Even though stem cell therapies are still under experimentation, the media has represented them as a panacea that would cure all diseases. This fact secured the authorization for using human embryos as research material. Therapies include manipulation of human material in tissue bioengineering, suggesting a representation of the body as a factory. This article describes stem cell research projects being carried out in the health sciences center of a higher education institution, focusing on field organization and on the system of values underlying scientific activity. Researchers at different levels were interviewed about perspectives on, and implications of, their research in order to analyze the discourse of the projects' participants. Experiments with adult stem cells enjoyed wide support, while the use of human embryos was disputed. The foundations of those arguments were sought in their relation both to the structure of the scientific field and to the researchers' religious background.

  20. Basic or clinical research of several parasitoses in China

    Institute of Scientific and Technical Information of China (English)

    蒋次鹏

    2002-01-01

    @@ In this special issue, a few research papers, in the field of medic al parasitology are related to protozoa (viseral leishmaniasis, toxoplasmosis, giardiasis), trematode (schistosomiasis), cestode (echinococcosis) and medical in sect (myiasis) from different institutions in China are presented.

  1. Why our patients (and we) need basic science research

    OpenAIRE

    Schor, Nina F.

    2013-01-01

    In times of fiscal austerity, the tendency is to seek instant, inexpensive gratification. In the case of biomedical research, this means the shortest path to practical clinical implementation. But fueling the translational pipeline with discovery depends critically on allowing the biomedical research community to follow their science where it takes them. Fiscal constraints carry with them the risk of squelching creativity and forfeiting the power of serendipity to provide the substrate for th...

  2. The application of 10CFR830. 120 in a basic research environment

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1991-04-01

    In this paper, I describe the process of applying the 10 basic criteria of the proposed 10CFR830.120 to a basic research environment like Fermilab and discuss some of the issues associated with the implementation of such a program. I will also discuss some of the differences and similarities between the 18 basic elements of NQA-1 and the 10 criteria of 10CFR830.120 along with the more philosophical'' issues associated with performance versus process- based approach to quality in basic research.

  3. Melodic Intonation Therapy: Back to Basics for Future Research

    Directory of Open Access Journals (Sweden)

    Anna eZumbansen

    2014-01-01

    Full Text Available We present a critical review of the literature on Melodic intonation therapy (MIT, one of the most formalized treatments used by speech-language therapist in Broca’s aphasia. We suggest basic clarifications to enhance the scientific support of this promising treatment. First, MIT is a program, not a single speech facilitation technique. The goal of MIT is to restore propositional speech. The rational is that patients can learn a new way to speak through singing by using language-capable regions of the right cerebral hemisphere. We argue that many treatment programs covered in systematic reviews on MIT’s efficacy do not match MIT’s therapeutic goal and rationale. Second, we distinguish between the immediate effect of MIT’s main speech facilitation technique (i.e., intoned-speech and the effect of the entire program on language recovery. Many results in the MIT literature can be explained by this duration factor. Finally, we propose that MIT can be viewed as a treatment of apraxia of speech more than aphasia. This issue should be explored in future experimental studies.

  4. Decellularized myocardial matrix hydrogels: In basic research and preclinical studies.

    Science.gov (United States)

    Wang, Raymond M; Christman, Karen L

    2016-01-15

    A variety of decellularized materials have been developed that have demonstrated potential for treating cardiovascular diseases and improving our understanding of cardiac development. Of these biomaterials, decellularized myocardial matrix hydrogels have shown great promise for creating cellular microenvironments representative of the native cardiac tissue and treating the heart after a myocardial infarction. Decellularized myocardial matrix hydrogels derived from porcine cardiac tissue form a nanofibrous hydrogel once thermally induced at physiological temperatures. Use of isolated cardiac extracellular matrix in 2D and 3D in vitro platforms has demonstrated the capability to provide tissue specific cues for cardiac cell growth and differentiation. Testing of the myocardial matrix hydrogel as a therapy after myocardial infarction in both small and large animal models has demonstrated improved left ventricular function, increased cardiac muscle, and cellular recruitment into the treated infarct. Based on these results, steps are currently being taken to translate these hydrogels into a clinically used injectable biomaterial therapy. In this review, we will focus on the basic science and preclinical studies that have accelerated the development of decellularized myocardial matrix hydrogels into an emerging novel therapy for treating the heart after a myocardial infarction.

  5. Artificial Sight Basic Research, Biomedical Engineering, and Clinical Advances

    CERN Document Server

    Humayun, Mark S; Chader, Gerald; Greenbaum, Elias

    2008-01-01

    Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting. The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research. Key Features Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical...

  6. Exploratory flight investigation of aircraft response to the wing vortex wake generated by the augmentor wing jet STOL research aircraft

    Science.gov (United States)

    Jacobsen, R. A.; Drinkwater, F. J., III

    1975-01-01

    A brief exploratory flight program was conducted at Ames Research Center to investigate the vortex wake hazard of a powered-lift STOL aircraft. The study was made by flying an instrumented Cessna 210 aircraft into the wake of the augmentor wing jet STOL research aircraft at separation distances from 1 to 4 n.mi. Characteristics of the wake were evaluated in terms of the magnitude of the upset of the probing aircraft. Results indicated that within 1 n.mi. separation the wake could cause rolling moments in excess of roll control power and yawing moments equivalent to rudder control power of the probe aircraft. Subjective evaluations by the pilots of the Cessna 210 aircraft, supported by response measurements, indicated that the upset caused by the wake of the STOL aircraft was comparable to that of a DC-9 in the landing configuration.

  7. Basic research needs and opportunities on interfaces in solar materials

    Energy Technology Data Exchange (ETDEWEB)

    Czanderna, A. W.; Gottschall, R. J. [eds.

    1981-04-01

    The workshop on research needs and recommended research programs on interfaces in solar energy conversion devices was held June 30-July 3, 1980. The papers deal mainly with solid-solid, solid-liquid, and solid-gas interfaces, sometimes involving multilayer solid-solid interfaces. They deal mainly with instrumental techniques of studying these interfaces so they can be optimized, so they can be fabricated with quality control and so changes with time can be forecast. The latter is required because a long lifetime (20 yrs is suggested) is necessary for economic reasons. Fifteen papers have been entered individually into EDB and ERA. (LTN)

  8. Future topics in basic nucleation and growth research

    International Nuclear Information System (INIS)

    An adequate knowledge of nucleation and growth processes leads to the design and manufacture of thin film deposits of desired properties. Research in randon heterogeneous nucleation, epitaxial nucleation and growth, angstrom-particle chemistry, and surface replication with atomistic resolution is discussed

  9. Teaching Medical Students Basic Neurotransmitter Pharmacology Using Primary Research Resources

    Science.gov (United States)

    Halliday, Amy C.; Devonshire, Ian M.; Greenfield, Susan A.; Dommett, Eleanor J.

    2010-01-01

    Teaching pharmacology to medical students has long been seen as a challenge, and one to which a number of innovative approaches have been taken. In this article, we describe and evaluate the use of primary research articles in teaching second-year medical students both in terms of the information learned and the use of the papers themselves. We…

  10. Basic research in crystalline and noncrystalline ceramic systems. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Kingery, W. D.; Coble, R. L.

    1968-04-01

    Various research subjects on ceramics have been investigated, including heat conduction, surface characteristics, diffusion in oxides, high-temperature kinetic processes, microstructure development, effects of microstructure on properties, structure and properties of noncrystalline ceramics, dissolution kinetics, and solid-vapor reactions. (DLC)

  11. Using Calibrated Peer Review to Teach Basic Research Skills

    Science.gov (United States)

    Bracke, Marianne S.; Graveel, John G.

    2014-01-01

    Calibrated Peer Review (CPR) is an online tool being used in the class Introduction to Agriculture and Purdue University (AGR 10100) to integrate a writing and research component (http://cpr.molsci.ucla.edu/Home.aspx). Calibrated Peer Review combines the ability to create writing intensive assignments with an introduction to the peer-review…

  12. Superconductors at the nanoscale from basic research to applications

    CERN Document Server

    Moshchalkov, Victor; Bending, Simon; Tafuri, Francesco

    2017-01-01

    By covering theory, design and fabrication of nanostructured superconducting materials, this monograph is an invaluable resource for research and development. Examples are energy saving solutions for industrial applications in the areas of electricity grids, healthcare, and communication technologies. Key ingredients are nanopatterned materials which help to improve the superconducting critical parameters and lead to novel functionalities.

  13. Basic Research in HIV vaccinology is hampered by reductionist thinking

    Directory of Open Access Journals (Sweden)

    Marc H V Van Regenmortel

    2012-07-01

    Full Text Available This review describes the structure-based reverse vaccinology approach aimed at developing vaccine immunogens capable of inducing antibodies that broadly neutralize HIV-1. Some basic principles of protein immunochemistry are reviewed and the implications of the extensive polyspecificity of antibodies for vaccine development are underlined. Although it is natural for investigators to want to know the cause of an effective immunological intervention, the classic notion of causality is shown to have little explanatory value for a system as complex as the immune system, where any observed effect always results from many interactions between a large number of components. Causal explanations are reductive because a single factor is singled out for attention and given undue explanatory weight on its own. Other examples of the negative impact of reductionist thinking on HIV vaccine development are discussed. These include 1 the failure to distinguish between the chemical nature of antigenicity and the biological nature of immunogenicity, 2 the belief that when an HIV-1 epitope is reconstructed by rational design to better fit a neutralizing Mab, this will produce an immunogen able to elicit Abs with the same neutralizing capacity as the Ab used as template for designing the antigen 3 the belief that protection against infection can be analysed at the level of individual molecular interactions although it has meaning only at the level of an entire organism.The numerous unsuccessful strategies that have been used to design HIV-1 vaccine immunogens are described and it is suggested that the convergence of so many negative experimental results, justifies the conclusion that reverse vaccinology is unlikely to lead to the development of a preventive HIV-1 vaccine. Immune correlates of protection in vaccinees have not yet been identified because this will become feasible only retrospectively once an effective vaccine exists.

  14. Crystallography for university research: some basic case studies.

    Science.gov (United States)

    Crochet, Aurelien

    2014-01-01

    An overview of commonly available, state-of-the-art diffraction techniques for university research is presented based on some chemical case studies. Examples from the Fribourg crystallography service are presented, aimed at scientists who would like to learn about the principal possibilities that X-ray powder and single-crystal diffraction can offer, how these methods can serve to determine the structure of a given material, and how they can help to identify polymorphs, surface coatings and enantiomers.

  15. Research of basic forms of realization of international business

    OpenAIRE

    Сазонець, Ольга Миколаївна; Качан, Олена Іванівна

    2015-01-01

    For the successful functioning of the national economy it is necessary for a state to participate in external economic relations, which draws the increasing of the volume of international business. After determining the nature of relationships and selection of the target market cooperation it is important to choose the form of the international relations. The purpose of this research has been to investigate current forms and ways of international enterprise activity which enabled to specify, ...

  16. REVISITING NEW INSTITUTIONAL ECONOMICS: BASIC CONCEPTS AND RESEARCH DIRECTIONS

    OpenAIRE

    Zoran Stefanovic, Branislav Mitrovic

    2015-01-01

    In the last four decades there is a renewed interest within the economic theory for the institutional structures. Numerous, multiple and often unpredictable effects of institutions on economic process are differently reflected among the leading schools of economic analysis. Certainly, in this sense, the greatest attention should be given to the stream of economic thought known as institutional economics. This heterogeneous research orientation today is already clearly differentiated on Veblen...

  17. Tumor banks: the cornerstone of basic research in urology

    Directory of Open Access Journals (Sweden)

    Sabrina T. Reis

    2010-06-01

    Full Text Available PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C. A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment.

  18. Adult Basic Skills: Innovations in Measurement and Policy Analysis. Series on Literacy: Research, Policy, and Practice.

    Science.gov (United States)

    Tuijnman, Albert C., Ed.; Kirsch, Irwin S., Ed.; Wagner, Daniel A., Ed.

    This book contains 13 papers examining innovations in measuring adults' basic skills and analyzing adult literacy policy. The following papers are included: "Series Preface" (Daniel A. Wagner); "Foreword" (Torsten Husen); "Introduction" (Albert Tuijnman); "Adult Basic Skills: Policy Issues and a Research Agenda" (David Stern, Albert Tuijnman);…

  19. Basic Histopathological Methods and Breast Lesion Types for Research.

    Science.gov (United States)

    Ouyang, Nengtai; Wang, Lin

    2016-01-01

    The in situ observation on the tissues, such as histopathology, immunohistochemistry (IHC), immunofluorescence (IF), and in situ hybridization (ISH), is one of the most important methods in the biomedical scientific research. In this chapter we introduce the most often used methods-hematoxylin and eosin (H&E) and double IF staining. H&E staining is used for general morphology by which the different pathological types of breast lesions are identified. The double IF staining is often used to study the protein-protein interaction on tissues for signaling mechanisms. This chapter also includes the histopathology of primary or simplified breast lesion types that is essential for applying the above methods and the reclassification of breast cancers by molecular markers.

  20. Basic research needs to assure a secure energy future. A report from the Basic Energy Sciences Advisory Committee

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-02-01

    This report has highlighted many of the possible fundamental research areas that will help our country avoid a future energy crisis. The report may not have adequately captured the atmosphere of concern that permeated the discussions at the workshop. The difficulties facing our nation and the world in meeting our energy needs over the next several decades are very challenging. It was generally felt that traditional solutions and approaches will not solve the total energy problem. Knowledge that does not exist must be obtained to address both the quantity of energy needed to increase the standard of living world-wide and the quality of energy generation needed to preserve the environment. In terms of investments, it was clear that there is no single research area that will secure the future energy supply. A diverse range of economic energy sources will be required--and a broad range of fundamental research is needed to enable these. Many of the issues fall into the traditional materials and chemical sciences research areas, but with specific emphasis on understanding mechanisms, energy related phenomena, and pursuing novel directions in, for example, nanoscience and integrated modeling. An important result from the discussions, which is hopefully apparent from the brief presentations above, is that the problems that must be dealt with are truly multidisciplinary. This means that they require the participation of investigators with different skill sets. Basic science skills have to be complemented by awareness of the overall nature of the problem in a national and world context, and with knowledge of the engineering, design, and control issues in any eventual solution. It is necessary to find ways in which this can be done while still preserving the ability to do first-class basic science. The traditional structure of research, with specific disciplinary groupings, will not be sufficient. This presents great challenges and opportunities for the funders of the

  1. Basic Research Needs for Clean and Efficient Combustion of 21st Century Transportation Fuels

    Energy Technology Data Exchange (ETDEWEB)

    McIlroy, A.; McRae, G.; Sick, V.; Siebers, D. L.; Westbrook, C. K.; Smith, P. J.; Taatjes, C.; Trouve, A.; Wagner, A. F.; Rohlfing, E.; Manley, D.; Tully, F.; Hilderbrandt, R.; Green, W.; Marceau, D.; O' Neal, J.; Lyday, M.; Cebulski, F.; Garcia, T. R.; Strong, D.

    2006-11-01

    To identify basic research needs and opportunities underlying utilization of evolving transportation fuels, with a focus on new or emerging science challenges that have the potential for significant long-term impact on fuel efficiency and emissions.

  2. 包容性领导的探索性研究%Exploratory Research on Inclusive Leadership

    Institute of Scientific and Technical Information of China (English)

    段诚; 唐宁玉

    2016-01-01

    It is now a popular topic to research on inclusive leadership,however there is no unified opinion about inclusive leadership in research field.Based on Chinese culture about the understanding of inclusion,this research reviews past research on inclusive leadership,and through exploratory research especially through interview, I make a definition of inclusive leadership and propose some value about inclusive leadership.%包容性领导的概念正在成为研究的热点,目前对包容性领导的定义,学术界没有统一的认识,基于中国文化对包容性概念的理解,梳理包容性相关学术研究、文献,通过探索性访谈研究,对包容性领导的概念进行了定义,并提出包容性领导的价值。

  3. New directions for QA in basic research: The Fermilab/DOE-CH experience

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.

    1989-09-01

    This paper addresses the underlying problems involved in developing institution-wide QA programs at DOE funded basic research facilities, and suggests concrete ways in which QA professionals and basic researchers can find common ground in describing and analyzing those activities to the satisfaction of both communities. The paper is designed to be a springboard into workshop discussions which can define a path for developing institution-wide QA programs based on the experience gained with DOE-CH and Fermilab.

  4. Basic research in crystalline and noncrystalline ceramic systems. Annual report, August 1, 1980-October 31, 1981

    International Nuclear Information System (INIS)

    The Basic Research Programs in Ceramics sponsored by the US Department of Energy supports a significant fraction of the research effort and graduate student training in ceramics at MIT. Various research activities involving ceramic materials include electrical properties; kinetic studies; defect structures, defect interactions, grain boundaries and surfaces; sintering studies; and mechanical properties

  5. Basic science and energy research sector profile: Background for the National Energy Strategy

    Energy Technology Data Exchange (ETDEWEB)

    March, F.; Ashton, W.B.; Kinzey, B.R.; McDonald, S.C.; Lee, V.E.

    1990-11-01

    This Profile report provides a general perspective on the role of basic science in the spectrum of research and development in the United States, and basic research's contributions to the goals of the National Energy Strategy (NES). It includes selected facts, figures, and analysis of strategic issues affecting the future of science in the United States. It is provided as background for people from government, the private sector, academia, and the public, who will be reviewing the NES in the coming months; and it is intended to serve as the basis for discussion of basic science issues within the context of the developing NES.

  6. The social ecology of girls' bullying practices: exploratory research in two London schools.

    Science.gov (United States)

    Jamal, Farah; Bonell, Chris; Harden, Angela; Lorenc, Theo

    2015-06-01

    This exploratory study adopts a socio-ecological approach to examine the context of school bullying. It asks: (1) what are students' accounts of bullying practices?; (2) how are these enabled and constrained by the school-environment?; (3) how is gender implicated? Qualitative data were collected from girls in two schools in London via focus groups (one in each school; students aged 12-15) and seven semi-structured interviews (in one school; students aged 16-18); and from school policy documents. Our interpretation of girls' accounts, informed by Giddens' structuration theory, suggests that bullying practices were spatially patterned in the schools and often characterised by the regulation of girls' sexuality and sexual-harassment. Repeated acts of aggression were fluid with regard to the bully and victim role, challenging the dominant view of bullying as characterised by consistent disparities in power between individuals. Schools structured bullying behaviour via policies and practices that ignored these forms of abuse and which focused on and may have been complicit in the making of stable 'bully' and 'victim' roles, thus indirectly contributing to the reproduction of unhealthy relationships between students. In terms of gender, traditional gendered and sexual discourses appear to structure the identities of the schools and girls in our study.

  7. Basic research in crystalline and noncrystalline ceramic systems. Annual report, August 1, 1979-October 31, 1980

    International Nuclear Information System (INIS)

    The Basic Research Programs in Ceramics supports a significant fraction of the research effort and graduate student training in ceramics at M.I.T. The importance of basic research programs in ceramics processing and properties is becoming widely recognized as the critical role of improved ceramic materials for energy systems is acknowledged. The needs identified in the 1977 series of workshops on DOE programs in energy-related materials research and by the ongoing efforts of the DOE Council on Materials Science are being translated into the basic and applied research necessary to fulfill the established objectives in the effort to solve the nation's energy problems. Present indications are that ceramics in numerous applications will be critical in meeting national energy requirements

  8. A roadmap for bridging basic and applied research in forensic entomology.

    Science.gov (United States)

    Tomberlin, J K; Mohr, R; Benbow, M E; Tarone, A M; VanLaerhoven, S

    2011-01-01

    The National Research Council issued a report in 2009 that heavily criticized the forensic sciences. The report made several recommendations that if addressed would allow the forensic sciences to develop a stronger scientific foundation. We suggest a roadmap for decomposition ecology and forensic entomology hinging on a framework built on basic research concepts in ecology, evolution, and genetics. Unifying both basic and applied research fields under a common umbrella of terminology and structure would facilitate communication in the field and the production of scientific results. It would also help to identify novel research areas leading to a better understanding of principal underpinnings governing ecosystem structure, function, and evolution while increasing the accuracy of and ability to interpret entomological evidence collected from crime scenes. By following the proposed roadmap, a bridge can be built between basic and applied decomposition ecology research, culminating in science that could withstand the rigors of emerging legal and cultural expectations.

  9. An exploratory study to develop a practical ethical framework for reproductive health research

    OpenAIRE

    Tahmineh Farajkhoda; Robab Latifnejad Roudsari; Mahmoud Abbasi

    2013-01-01

    Background: Research in reproductive health (RH) has been located in the core of women’s health research. Providing accurate information through conducting scientific and controlled research is essential, but increased number of research in the world especially in developing countries in RH area in order to introduce advanced technologies has been resulted in much unethical, illegal and abusive research on women, which needs particular attention to ethical issues by the practitioners who are ...

  10. Exploratory research on bioactive natural products with a focus on biological phenomena

    OpenAIRE

    Uemura, Daisuke

    2010-01-01

    The discovery of new basic compounds holds the key for advancing material sciences. We have focused on the identification and characterization of natural key compounds that control biologically and physiologically intriguing phenomena. The discovery of new bioactive molecules, facilitated by a deeper understanding of nature, should advance our knowledge of biological processes and lead to new strategies to treat disease. The structure and function of natural compounds are sometimes unexpected...

  11. Laser acupuncture - innovative basic research: visual and laser-induced evoked potentials

    OpenAIRE

    Litscher, Gerhard

    2012-01-01

    Background and aims: Laser acupuncture is a therapeutic medical method. Innovative basic research is necessary within this fascinating area of research. This publication focuses on visual evoked potentials (VEP) elucidated by non-invasive and partially non-perceptible laser stimulation.

  12. CAS Scientists Play an Important Role in National Basic Research Program

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Of the 39 research projects that kicked off in 2005 with the support from the NationalBasic Research Program (dubbed the 973 Program) across the country, 12 are hosted byCAS scientists (including two under the joint leadership with other departments).

  13. A ProCoS II Project Final Report: ESPRIT Basic Research project 707

    DEFF Research Database (Denmark)

    Bowen, J. P.; Hoare, C. A. R.; Langmaack, Hans;

    1996-01-01

    An overview of the research and associated activities of the Europeancollaborative ESPRIT Basic Research ProCoS II project (no. 7071) on``Provably Correct Systems'' which ran from 1992 to 1995 is presented.This was a follow-on project to ProCoS (no. 3104) and ran inparallel with the ProCoS Working...

  14. Making Life Easier with Effort: Basic Findings and Applied Research on Response Effort.

    Science.gov (United States)

    Friman, Patrick C.; Poling, Alan

    1995-01-01

    This paper summarizes basic research on response effort in diverse applied areas including deceleration of aberrant behavior, attention deficit-hyperactivity disorder, oral habits, littering, and problem solving. The paper concludes that response effort as an independent variable has potent effects, and research exploring the applied benefits of…

  15. Patenting productivity and intellectual property policies at Research I universities: An exploratory comparative study.

    Directory of Open Access Journals (Sweden)

    Pilar Mendoza

    2005-01-01

    Full Text Available In the 1980s, the US government encouraged the cooperation of industries with universities in order to bridge funding gaps and cope with global competitive markets through legislations that allow universities to start spin-off businesses and to generate profits from patents. At the turn of the century, university partnerships with the private sector have greatly increased through research grants, licensing patents, and in some cases, the formation of new firms'mainly at research universities and in the hard sciences. In response to these entrepreneurial opportunities, university administrators developed intellectual property policies to facilitate the commercialization of research. The purpose of this study is to explore the differences across IP policies among nine research universities as potential sources of influence on faculty engagement in for-profit research ventures according to existing models of faculty role performance and achievement.

  16. Basic research on nonlinear instability phenomena of liquid surface. Fiscal year 1996 report on preceding basic engineering field

    Energy Technology Data Exchange (ETDEWEB)

    Madarame, Haruki; Okamoto, Koji [Tokyo Univ., Tokai, Ibaraki (Japan). Nuclear Engineering Research Lab.; Iida, Masao

    1997-03-01

    Various nonlinear behaviors caused by nonlinear boundary conditions have been observed, and it is feared that in large vessels like FBRs, the instability phenomena such as self-exciting sloshing may occur in the free liquid surface of coolant. In this research, the nonlinear instability phenomena in free liquid surface were examined by the basic experiment and the analysis. As to the self-exciting oscillation `jet flutter` of upward plane jet that collides against liquid surface, in order to know the mechanism of determining the frequency and supplying energy, the amplitude and phase relation of various variable quantities were investigated. The simplified model for calculating the displacement of jet was made, and compared with the experiment. The jet flutter phenomena are explained. The interaction of free liquid surface and turbulent flow, which is important for considering the nonlinearity in free liquid surface, was measured by LDV and visualization, and the turbulent flow phenomena in free liquid surface were investigated. In the experiment, turbulent flow energy was given to the free liquid surfaces of water and polymers, and the effect that the Toms effect exerted to interface turbulent flow was observed. The results of these studies are reported. (K.I.)

  17. Informal interactions between audit committees and internal audit functions: exploratory evidence and directions for future research

    OpenAIRE

    Mahbub Zaman

    2013-01-01

    Purpose:This paper recognises the importance of informal processes within corporate governance and complements existing research in this area by investigating factors associated with the existence of informal interactions between audit committees and internal audit functions and in providing directions for future research.Design/Methodology/Approach:To examine the existence and drivers of informal interactions between audit committees and internal audit functions, this paper relies on a quest...

  18. Transformational leadership : exploratory study within research and development (R&D) groups / Genevieve Joorst.

    OpenAIRE

    Joorst, Genevieve

    2009-01-01

    This research investigated the leadership style in a research and development (R&D) work unit within a petro-chemical company, using the Full Range Leadership Development Theory as assessed by Multifactor-Leadership-Questionnaire (MLQ). From the literature review conducted, it was concluded that an R&D environment is multi-dimensional and the workforce can be diverse in the field of specialisation and personality characteristics. Subsequently, the literature review also focused on functional ...

  19. Exploratory investigation of the need for and feasibility of a Lower Atmosphere Research Satellite (LARS) program

    Science.gov (United States)

    1980-01-01

    The need for and feasibility of a research satellite program for the intensive study of the lower atmosphere (the troposphere and lower stratosphere) is discussed. The priorities for scientific investigation of the lower atmosphere during the next decade are examined. The findings of the study are concerned with identification of those broad research issues of highest priority and, in particular, with those that are most appropriate for investigation from space platforms.

  20. Evaluation of mid-to-long term basic research for environmental restoration

    International Nuclear Information System (INIS)

    This document describes a long-term basic research program for the US Department of Energy (DOE) that complements departmental initiatives in waste management and site cleanup. The most important problems faced by DOE are environmental restoration of waste sites and cleanup of inactive facilities. Environmental restoration is defined in this report as characterization, assessment, remediation, and post-closure verification within the waste/environmental system at DOE sites. Remediation of inactive, contaminated waste-disposal sites is the largest and most expensive task facing DOE. Immobilization, isolation, separation, and destruction of waste, either aboveground or in situ, are difficult and costly tasks. Technologies for these tasks are primitive or do not exist. Departmental problems in the long term are being analyzed scientifically and research needs are being identified. When completed, the Office of Energy Research's (OER's) basis research plan will describe potential scientific research needs for universities, national laboratories, and others as a basis for research proposals to DOE. Extensive interaction with the scientific community is planned to further refine and prioritize research needs. Basic research within DOE is directed toward fundamental knowledge leading to the discovery of new scientific or engineering concepts and principles that may or may not have immediate specific technological applications. However, because DOE is a mission-oriented agency, basic research in DOE is strongly influenced by national energy and environmental policy and may be multidisciplinary in nature. Basic research will provide innovative concepts and the fundamental knowledge base that facilitates the development and application of new and emerging technologies. 41 refs., 5 figs., 9 tabs

  1. The outline report of advanced basic engineering research in the fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The JNC has initiated the cooperation with universities and research institutes for advanced basic engineering on 1995. The number of research cooperation theme is increasing and satisfactorily improving in the forth year, 1998. The objective of this program is to promote the advanced basic engineering research with universities and research institutes in relation with the JNC's projects. The facilities and equipment of the JNC are mainly provided to the cooperation. The JNC has settled the research cooperation themes. The universities and research institute have applied to the themes with their issues, working plans and personnel. The JNC has selected the issues and personnel, and put into practice the cooperation with accepting guest staffs and/or research fellows from the universities. This report summarizes the results of the advanced basic engineering research cooperation executed in the fiscal year, 1998. The total number of issues is 34 for the 29 themes; those are categorized in to two groups. The one is related to the fast breeder reactor technologies and the other is on the environmental technologies. The 12 issues are finished in the fiscal year, 1998, in which the 9 issues are for the fast breeder reactor technologies and the 3 issues are for the environmental technologies. The themes/the issues, the host group, host key persons, university side key persons, a form of cooperation are summarized in the tables. The summary reports of research activities by the all cooperators are presented under the particular format. Those describe the total schedule, a form of cooperation, the research objective, the outline of research contents, main facilities for using, research status, research results, future schedules and bibliographies relevant to the research cooperation. The 25 tables and 158 figures are included. (Y. Tanaka)

  2. Marketing Strategies in Port Industry: An Exploratory Study and a Research Agenda

    Directory of Open Access Journals (Sweden)

    Angelos M. Pantouvakis

    2010-01-01

    Full Text Available Problem statement: Market globalization increases demand and the competition between firms. Ports as basic figurative nodes cannot remain separate from this change. Technological improvements, the increased demand of marine transports, the demand for new, bigger and more specialized vessels, has increased the competition among ports. Approach: In this competitive environment business mistakes may be proved fatal and marketing strategies arise as a means for differentiation. As such, modern ports suffer both from internal and external pressures. On the one hand, they need to exhibit management competency in the pursuit of suitable strategy and in the allocation of scarce resources. On the other, they no longer enjoy the freedom of a monopoly and therefore face a completely competitive market. Results: The selection of a suitable strategy is important for ports wishing to improve their financial results. The better financial capability for a firm means investing in the constantly changing shipping market. Economic prosperity also adds value to a firm that uses suitable marketing strategies to satisfy its customers. Conclusion: The present richer examined two alternative strategies-profit maximization and revenue maximization-and explores the factors that influence the application of these two strategies in the port industry. Data from 18 European ports were examined by multiple step-wise regression. The results proved the diversity of the two applications.

  3. Designing Libraries for Research Collaboration in the Network World: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Sheila Corrall

    2014-08-01

    Full Text Available Advances in technology and changes in higher education and research are forcing libraries to rethink the services they offer to researchers and how they are presented. Librarians are moving into “higher end support” and adopting new service models based on “deep collaboration” with academic partners. The internal arrangements that form the design of an organization can determine whether it achieves its mission under particular conditions. The present study explores how libraries in 24 leading UK research universities are organizing resources and services to support the research enterprise. Qualitative data were collected from institutional websites and other public domain sources and were analysed using matrix techniques. The results show a trend away from integrated library and computing service organizations; variety in institutional reporting lines, but predominantly in large professional service groups; consistency in internal library groupings, but variation in portfolio and job titles; expansion of specialist positions, with new functional roles complementing traditional subject liaisons; and dedicated spaces, working groups, and integrated websites promoting boundary-spanning activities. The findings confirm and extend prior work and are being used to design a large scale international survey.

  4. The Use of Electronic Journals by Dutch Researchers: A Descriptive and Exploratory Study

    Science.gov (United States)

    Voorbij, Henk; Ongering, Hilde

    2006-01-01

    Dutch faculty was surveyed as to their use of electronic journals. It was concluded that electronic journals have become indispensable for scientists and social scientists, and have a profound effect on information behavior, varying from methods of becoming aware of relevant articles to benefits on research.

  5. Moving in Unexpected Directions: Texas Elementary Uses Exploratory Research to Map Out an Evaluation Plan

    Science.gov (United States)

    Chapman, Sue; Ortloff, Debora; Weaver, Laurie; Vesey, Winona; Anderson, Mary; Marquez, Michael; Sanchez, Melissa

    2013-01-01

    This article describes the actions taken by the members of the school leadership team at McWhirter Elementary Professional Development Laboratory School in Webster, Texas, when the results of the state reading assessment in spring 2010, had taken a sudden and dramatic drop from the previous year. The team designed an action research study to…

  6. Exploratory Factor Analysis as a Construct Validation Tool: (Mis)applications in Applied Linguistics Research

    Science.gov (United States)

    Karami, Hossein

    2015-01-01

    Factor analysis has been frequently exploited in applied research to provide evidence about the underlying factors in various measurement instruments. A close inspection of a large number of studies published in leading applied linguistic journals shows that there is a misconception among applied linguists as to the relative merits of exploratory…

  7. 32 CFR Appendix A to Part 272 - Principles for the Conduct and Support of Basic Research

    Science.gov (United States)

    2010-07-01

    ... Research A Appendix A to Part 272 National Defense Department of Defense (Continued) OFFICE OF THE... DEPARTMENT OF DEFENSE Pt. 272, App. A Appendix A to Part 272—Principles for the Conduct and Support of Basic... investments as a portfolio, with assessments of program success based on aggregate returns. There should be...

  8. From Research to Practice: Basic Mathematics Skills and Success in Introductory Statistics

    Science.gov (United States)

    Lunsford, M. Leigh; Poplin, Phillip

    2011-01-01

    Based on previous research of Johnson and Kuennen (2006), we conducted a study to determine factors that would possibly predict student success in an introductory statistics course. Our results were similar to Johnson and Kuennen in that we found students' basic mathematical skills, as measured on a test created by Johnson and Kuennen, were a…

  9. AN EXPLORATORY RESEARCH REGARDING CUSTOMER ORIENTATION AND PERFORMANCE IN HOSPITALITY INDUSTRY

    Directory of Open Access Journals (Sweden)

    FLAVIA DANA OLTEAN

    2013-08-01

    Full Text Available The main objective of this research is to present the importance of the customer orientation from themanagerial perspective and to analyze the influence of customer orientation over the performance indicators in thehotels from Mures county (Romania . For achieving this objective, the data have been collected by means of 42surveys addressed to managers and owners who are active in the industry of hospitability, and the results indicated apartial confirmation of the tested hypotheses and the results from previous international research. The conclusions ofthe study present importance for the decisional authorities associated with hotel units which desire to achieve thesatisfaction of the customers, gaining the brand loyalty and implicitly the desired economic efficiency and add to theinternational literature aspects referring to the industry of hospitality from Romania.

  10. Willingness to pay for basic research: a contingent valuation experiment on the large hadron collider

    CERN Document Server

    Catalano, Gelsomina; Giffoni, Francesco

    2016-01-01

    An increasing number of countries and institutions are investing in large-scale research infrastructures (RIs) and in basic research. Scientific discoveries, which are expected thanks to RIs, may have a non-use value, in analogy with environmental and cultural public goods. This paper provides, for the first time, an empirical estimation of the willingness to pay (WTP) for discoveries in basic research by the general public. We focus on the Large Hadron Collider (LHC), the largest particle accelerator worldwide, where in 2012 the Higgs boson was discovered. Nobody knows the practical value of such discovery, beyond knowledge per se. The findings of our study are based on a dichotomous choice contingent valuation (CV) survey carried out in line with the NOAA guidelines. The survey involved 1,022 undergraduate students enrolled in more than 30 different degrees (including the humanities) at five universities located in four countries (Italy, France, Spain, UK). We ask two main research questions: Which are the ...

  11. AN EXPLORATORY RESEARCH REGARDING CUSTOMER ORIENTATION AND PERFORMANCE IN HOSPITALITY INDUSTRY

    OpenAIRE

    FLAVIA DANA OLTEAN

    2013-01-01

    The main objective of this research is to present the importance of the customer orientation from the managerial perspective and to analyze the influence of customer orientation over the performance indicators in the hotels from Mures county (Romania ). For achieving this objective, the data have been collected by means of 42 surveys addressed to managers and owners who are active in the industry of hospitability, and the results indicated a partial confirmation of the tested hypotheses and t...

  12. An exploratory research on the role of family in youth's drug addiction

    OpenAIRE

    Masood, Sobia; Us Sahar, Najam

    2014-01-01

    Most of the researches in Pakistan are concerned with the aetiological factors of drug addiction among the youth. However, few studies seek to explore the social aspects of this phenomenon. The present study aimed to explore the role of family, the influence of parental involvement, and communication styles in youth's drug addiction in a qualitative manner. Twenty drug addicts (age range 18–28 years) were taken as a sample from drug rehabilitation centres in Rawalpindi and Islamabad, Pakistan...

  13. Web-Based Recruiting for Health Research Using a Social Networking Site: An Exploratory Study

    OpenAIRE

    Fenner, Yeshe; Suzanne M Garland; Moore, Elya E.; Jayasinghe, Yasmin; Fletcher, Ashley; Tabrizi, Sepehr N.; Gunasekaran, Bharathy; Wark, John D.

    2012-01-01

    Background Recruitment of young people for health research by traditional methods has become more expensive and challenging over recent decades. The Internet presents an opportunity for innovative recruitment modalities. Objective To assess the feasibility of recruiting young females using targeted advertising on the social networking site Facebook. Methods We placed an advertisement on Facebook from May to September 2010, inviting 16- to 25-year-old females from Victoria, Australia, to parti...

  14. Ethical Responsibility of Neuromarketing Companies in Harnessing the Market Research – a Global Exploratory Approach

    OpenAIRE

    Nicolae Al. Pop; Dan-Cristian Dabija; Ana Maria Iorga

    2014-01-01

    A key challenge in the 21st century is identifying how to satisfy consumers’ needs in the best manner possible, whilst ensuring companies’ financial profitability. Scientists play a major role in achieving this goal, as research methods, techniques and tools have continuously evolved. In the last two decades, the development of these instruments has seen an important boost, as neuromarketing methods and techniques added depth and accuracy to traditional studies. The main aim of...

  15. Attitudes toward medical and genetic confidentiality in the Saudi research biobank: An exploratory survey.

    Science.gov (United States)

    Alahmad, Ghiath; Hifnawy, Tamer; Abbasi, Badaruddin; Dierickx, Kris

    2016-03-01

    Achieving a balance between giving access to information and respecting donors' confidentiality is a crucial issue for any biobank, with its large number of samples and associated information. Despite the existence of much empirical literature on confidentiality, there are too few surveys in the Middle East about the topic, particularly in the Saudi context. A survey was conducted of 200 respondents at King Abdulaziz Medical City in Riyadh, Saudi Arabia, among 5 groups of equal size, comprised of researchers, physicians, medical students, donors and laypersons, respectively. The majority of participants agreed that confidentiality is an important issue and that it is well protected in the Saudi biobank. All 5 groups showed different attitudes toward disclosing information to various third parties. They were in favor of allowing treating physicians, and to a certain extent family members, to have access to medical and genetic results from research. No significant differences were found between views on medical and genetic confidentiality. The majority of respondents agreed that confidentiality might be breached in cases with specific justified reasons. Even considering differences in religion, culture and other factors, the results of the study were consistent with those reported in the literature and research conducted in other countries. We therefore place emphasis on the importance of protecting and promoting patient/donor confidentiality and privacy.

  16. 12th Meeting of China-Korea Joint Committee for Basic Scientific Research Held

    Institute of Scientific and Technical Information of China (English)

    Zhang Yongtao

    2008-01-01

    @@ The 12th Meeting of the China-Korea Joint Committee for Basic Scientific Research was successfully held in Xiamen,China from May 21 to 24,2008.Through evaluation,the Joint Committee selected 37 bilateral cooperative projects to grant in FY 2008,including 12 joint seminars and 25 joint research projects.The Committee members also made in-depth discussions on the issues of strengthening future cooperation and selecting the topics for the Northeastern Asian Symposium.

  17. Montreal Archive of Sleep Studies: an open-access resource for instrument benchmarking and exploratory research.

    Science.gov (United States)

    O'Reilly, Christian; Gosselin, Nadia; Carrier, Julie; Nielsen, Tore

    2014-12-01

    Manual processing of sleep recordings is extremely time-consuming. Efforts to automate this process have shown promising results, but automatic systems are generally evaluated on private databases, not allowing accurate cross-validation with other systems. In lacking a common benchmark, the relative performances of different systems are not compared easily and advances are compromised. To address this fundamental methodological impediment to sleep study, we propose an open-access database of polysomnographic biosignals. To build this database, whole-night recordings from 200 participants [97 males (aged 42.9 ± 19.8 years) and 103 females (aged 38.3 ± 18.9 years); age range: 18-76 years] were pooled from eight different research protocols performed in three different hospital-based sleep laboratories. All recordings feature a sampling frequency of 256 Hz and an electroencephalography (EEG) montage of 4-20 channels plus standard electro-oculography (EOG), electromyography (EMG), electrocardiography (ECG) and respiratory signals. Access to the database can be obtained through the Montreal Archive of Sleep Studies (MASS) website (http://www.ceams-carsm.ca/en/MASS), and requires only affiliation with a research institution and prior approval by the applicant's local ethical review board. Providing the research community with access to this free and open sleep database is expected to facilitate the development and cross-validation of sleep analysis automation systems. It is also expected that such a shared resource will be a catalyst for cross-centre collaborations on difficult topics such as improving inter-rater agreement on sleep stage scoring. PMID:24909981

  18. Montreal Archive of Sleep Studies: an open-access resource for instrument benchmarking and exploratory research.

    Science.gov (United States)

    O'Reilly, Christian; Gosselin, Nadia; Carrier, Julie; Nielsen, Tore

    2014-12-01

    Manual processing of sleep recordings is extremely time-consuming. Efforts to automate this process have shown promising results, but automatic systems are generally evaluated on private databases, not allowing accurate cross-validation with other systems. In lacking a common benchmark, the relative performances of different systems are not compared easily and advances are compromised. To address this fundamental methodological impediment to sleep study, we propose an open-access database of polysomnographic biosignals. To build this database, whole-night recordings from 200 participants [97 males (aged 42.9 ± 19.8 years) and 103 females (aged 38.3 ± 18.9 years); age range: 18-76 years] were pooled from eight different research protocols performed in three different hospital-based sleep laboratories. All recordings feature a sampling frequency of 256 Hz and an electroencephalography (EEG) montage of 4-20 channels plus standard electro-oculography (EOG), electromyography (EMG), electrocardiography (ECG) and respiratory signals. Access to the database can be obtained through the Montreal Archive of Sleep Studies (MASS) website (http://www.ceams-carsm.ca/en/MASS), and requires only affiliation with a research institution and prior approval by the applicant's local ethical review board. Providing the research community with access to this free and open sleep database is expected to facilitate the development and cross-validation of sleep analysis automation systems. It is also expected that such a shared resource will be a catalyst for cross-centre collaborations on difficult topics such as improving inter-rater agreement on sleep stage scoring.

  19. Attitudes and Causes of Cheating among Mexican College Students: An Exploratory Research

    Directory of Open Access Journals (Sweden)

    Edgardo arturo ayala gaytán

    2014-06-01

    Full Text Available This study extends the current state of literature on academic dishonesty, modeling the likelihood to engage in this practice in a private university in Mexico. Ten in-depth interviews with professors and college students were applied as a qualitative phase of the research in order to understand habits, experiences and perceptions about academic dishonesty. A survey with two hundred college students indicate that the number of incidents of cheating is significantly higher than standard estimations in the United States; the quality of students’ social networks is the most important factor explaining cheating and honor codes, whose perceived enforcement does not deter cheating.

  20. An exploratory research on the role of family in youth's drug addiction

    Science.gov (United States)

    Masood, Sobia; Us Sahar, Najam

    2014-01-01

    Most of the researches in Pakistan are concerned with the aetiological factors of drug addiction among the youth. However, few studies seek to explore the social aspects of this phenomenon. The present study aimed to explore the role of family, the influence of parental involvement, and communication styles in youth's drug addiction in a qualitative manner. Twenty drug addicts (age range 18–28 years) were taken as a sample from drug rehabilitation centres in Rawalpindi and Islamabad, Pakistan. A structured interview guide was administered comprising questions related to the individual's habits, relationship with family and friends, and modes of communication within the family. Case profiles of the participants were also taken. The rehabilitation centres offered family therapy and the researcher, as a non-participant, observed these sessions as part of the analysis. The demographic information revealed that majority of the participants were poly-substance abusers (80%) and the significant reasons for starting drugs were the company of peers and curiosity. The thematic analysis revealed parental involvement and emotional expressiveness as two major components in family communication. It was found that parents were concerned about their children, but were not assertive in the implementation of family rules. It was also found that the major life decisions of the participants were taken by their parents, which is a characteristic of collectivist Pakistani society. PMID:25750821

  1. THE EXPLORATORY RESEARCH OF THE EFFECT COMMUNICATION MODEL AND EFFECT IMPROVING STRATEGY OF INTERACTIVE ADVERTISING

    Directory of Open Access Journals (Sweden)

    Ding Wanxing

    2016-02-01

    Full Text Available Interactive advertising which characterized by interactivity has become the mainstream of advertising by gradually replacing traditional one-way advertising during the new media era. This paper has obeyed the research outline below, literature review, background description, assumption proposed, and empirical analysis. Therefore, this paper proposed the communication model of interactive advertising and drawn two related important conclusions, interactivity has brought positive effect to advertising communication, different type of consumers tend to use different interactive options in different ways. Furthermore, this paper also presented three related optimization strategies to improving the communication of interactive advertising, namely, 1.changing communication model from one-way to two-way, 2.renovating new communication process and effect-generated path, 3.renovating new strategy portfolio to improving the communication effect of interactive advertising.

  2. Glycan Arrays: From Basic Biochemical Research to Bioanalytical and Biomedical Applications

    Science.gov (United States)

    Geissner, Andreas; Seeberger, Peter H.

    2016-06-01

    A major branch of glycobiology and glycan-focused biomedicine studies the interaction between carbohydrates and other biopolymers, most importantly, glycan-binding proteins. Today, this research into glycan-biopolymer interaction is unthinkable without glycan arrays, tools that enable high-throughput analysis of carbohydrate interaction partners. Glycan arrays offer many applications in basic biochemical research, for example, defining the specificity of glycosyltransferases and lectins such as immune receptors. Biomedical applications include the characterization and surveillance of influenza strains, identification of biomarkers for cancer and infection, and profiling of immune responses to vaccines. Here, we review major applications of glycan arrays both in basic and applied research. Given the dynamic nature of this rapidly developing field, we focus on recent findings.

  3. Comparison Research of Statistical Method in Exploratory Factor Analysis%探索性因子分析中统计方法的比对研究

    Institute of Scientific and Technical Information of China (English)

    王娜

    2014-01-01

    Taking the selection of statistical method in exploratory factor analysis as the target, and in view of the distortion of calculation result due to improper selection of statistical methods in many literature using exploratory factor analysis, comparison research is done to the 15 statistical methods and suggestions are presented.%本文以探索性因子分析中统计方法的选择为目标,针对在许多应用探索性因子分析的文献中存在的统计方法选择不当致使计算结果失真这一现象,对探索性因子分析中的15种统计方法进行了比对研究,并给出了建议。

  4. VULNERABLE FACTORS OF SADNESS AMONG ADOLESCENTS ININDONESIA: AN EXPLORATORY INDIGENOUS RESEARCH

    Directory of Open Access Journals (Sweden)

    Kwartarini W. Yuniarti

    2012-03-01

    Full Text Available Adolescence is an unstable period in human’s life. Hurlock (2003called it as the phase of storm and stress. They easily get sad and angry.Aimed of this study was to identify the causes of sadness among male andfemale adolescents in order to prevent adolescent’s sadness. A total numberof 412 senior high school students (males =163 and females = 249completed open-ended questions asking about what makes them sad. Thesampling used in this research was the non-random sampling technique.Data analyzed by categorizing, open coding and cross tabulation. The resultsshowed that females feel sad when they have relationship problems (40,2%, deal with unexpected events (35, 3%, then personal problems (14,1%. Unlike female adolescents, the greatest cause of sadness for maleswas unexpected life events (42, 3%, then relationship problems (27%,and personal problems (15, 3%. This study concluded that femaleadolescents were more vulnerable towards relationship problems whichmade them sad, whilst male adolescents were more vulnerable towardlife’s distress.

  5. [Basic symptoms in schizophrenia, their clinical study and relevance in research].

    Science.gov (United States)

    Miret, Salvador; Fatjó-Vilas, Mar; Peralta, Víctor; Fañanás, Lourdes

    2016-01-01

    Basic symptoms consist of subtle sub-clinical disturbances subjectively experienced by schizophrenia patients. These are mainly related to drive, affect, thinking and language, perception, memory, motor action, central vegetative functions, control of cognitive processes, and stress tolerance. Initially described by Huber, from a phenomenological approach, basic symptoms are part of the earliest features of schizophrenia, and they can evolve along the course of the disorder. Their assessment during the prodromal phase of the disease (together with ultra-high risk criteria) is one of the 2 main approaches that allow the definition of states of clinical risk for the development of psychosis. The present review provides an updated view of the concept of basic symptoms, highlighting its potential value in establishing neurobiological correlates of interest in aetiopathogenic research. PMID:26774677

  6. Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium.

    Science.gov (United States)

    Amendola, Laura M; Jarvik, Gail P; Leo, Michael C; McLaughlin, Heather M; Akkari, Yassmine; Amaral, Michelle D; Berg, Jonathan S; Biswas, Sawona; Bowling, Kevin M; Conlin, Laura K; Cooper, Greg M; Dorschner, Michael O; Dulik, Matthew C; Ghazani, Arezou A; Ghosh, Rajarshi; Green, Robert C; Hart, Ragan; Horton, Carrie; Johnston, Jennifer J; Lebo, Matthew S; Milosavljevic, Aleksandar; Ou, Jeffrey; Pak, Christine M; Patel, Ronak Y; Punj, Sumit; Richards, Carolyn Sue; Salama, Joseph; Strande, Natasha T; Yang, Yaping; Plon, Sharon E; Biesecker, Leslie G; Rehm, Heidi L

    2016-06-01

    Evaluating the pathogenicity of a variant is challenging given the plethora of types of genetic evidence that laboratories consider. Deciding how to weigh each type of evidence is difficult, and standards have been needed. In 2015, the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) published guidelines for the assessment of variants in genes associated with Mendelian diseases. Nine molecular diagnostic laboratories involved in the Clinical Sequencing Exploratory Research (CSER) consortium piloted these guidelines on 99 variants spanning all categories (pathogenic, likely pathogenic, uncertain significance, likely benign, and benign). Nine variants were distributed to all laboratories, and the remaining 90 were evaluated by three laboratories. The laboratories classified each variant by using both the laboratory's own method and the ACMG-AMP criteria. The agreement between the two methods used within laboratories was high (K-alpha = 0.91) with 79% concordance. However, there was only 34% concordance for either classification system across laboratories. After consensus discussions and detailed review of the ACMG-AMP criteria, concordance increased to 71%. Causes of initial discordance in ACMG-AMP classifications were identified, and recommendations on clarification and increased specification of the ACMG-AMP criteria were made. In summary, although an initial pilot of the ACMG-AMP guidelines did not lead to increased concordance in variant interpretation, comparing variant interpretations to identify differences and having a common framework to facilitate resolution of those differences were beneficial for improving agreement, allowing iterative movement toward increased reporting consistency for variants in genes associated with monogenic disease.

  7. EXPLORATORY RESEARCH REGARDING ROMANIANS' PERCEPTION ABOUT THE REGIONAL BRAND “MARAMUREª”

    Directory of Open Access Journals (Sweden)

    Drule Alexandra-Maria

    2013-07-01

    Full Text Available In recent years, the expansion of touristic activities confirmed the importance of marketing activities in touristic regions. In tourism as well, globalization implies an unlimited number of options, and the traditional elements regarding competition and differences related to price or quality are no longer sufficient in efficiently differentiating the touristic region. A key factor in this sense is represented by the notion of place branding or, to be more precise, regional branding. Theoretical studies on this subject are relatively recent, and fewer compared with studies on traditional brands, for example. A practical research regarding a touristic region can thus provide a series of utile information that marketers can use in elaborating marketing strategies and, specifically, in the branding process. The study's main objective aimed at shaping the regional brand “Maramureº” using mainly projective techniques, scarcely used in studies of this kind in Romania, based on a sample of more than 200 respondents. The information obtained focused on the respondents' perceptions regarding the region of Maramureº as a touristic brand, the associations made, the values attributed to the region in terms of touristic potential, of touristic infrastructure, of weak and strong points of the touristic brand Maramureº, but also elements of the regional image and identity (at this point were considered certain associations with visual elements but also with its personality. By highlighting respondents' subjective and diverse opinions, it was aimed to point out some directions that would eventually guide a new approach of the brand for this touristic region. Also, the results of this study could represent a starting point for a program of regional development, funded through various local or European funds. Furthermore, based on the information obtained from respondents, it has been proposed a new logo of the region, as a first step in running a

  8. Exploratory Research on Simulation of CO2-Brine-Mineral Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Chen Zhu; Shiao hung Chiang

    2005-11-01

    Application of many carbon sequestration strategies requires knowledge of thermodynamic properties for the extremely complex chemical system of CO{sub 2}-SO{sub 2}-H{sub 2}O-NaCl-CaCl{sub 2}-MgCl{sub 2}. This University Coal Research Phase I program has been successful and highly productive in exploring an approach to develop an equation of state (EOS) to describe thermodynamic properties in the above chemical system. We have compiled available laboratory experimental data and thermodynamic models, and evaluated their appropriateness for the carbon sequestration process. Based on this literature review, we provided an improved CO{sub 2} solubility model for the CO{sub 2}-H{sub 2}O-NaCl system, which incorporates newly available experimental measurements funded by DOE, and is valid in temperature range from 273 to 533 K, pressure from 0 to 2000 bar, and salinity from 0 to 4.5 molality of NaCl equivalent. The improved model also greatly improves the computational efficiency of CO{sub 2} solubility calculations and thus is better suited to be incorporated into large computer simulation models (e.g., reservoir simulation models). The literature review and model development provided insights of the data needs and directions for future work. Synergetic collaboration with DOE scientists has resulted in simulations of injected CO{sub 2} fate in sandstone aquifer with a one-dimensional numerical coupled reactive transport model. We evaluated over 100 references on CO{sub 2} solubility and submitted two manuscripts to peer-reviewed journals. One paper has been accepted for publication in ''Environmental Geosciences''.

  9. Increasing the public health potential of basic research and the scientist satisfaction. An international survey of bioscientists

    OpenAIRE

    Scita, Giorgio; Sorrentino, Carmen; Boggio, Andrea; Hemenway, David; Ballabeni, Andrea

    2016-01-01

    Basic scientific research generates knowledge that has intrinsic value which is independent of future applications. Basic research may also lead to practical benefits, such as a new drug or diagnostic method.  Building on our previous study of basic biomedical and biological researchers at Harvard, we present findings from a new survey of similar scientists from three countries.  This survey asked about the scientists’ motivations, goals and perspectives along with their attitudes concerning ...

  10. Pluripotent stem cell-derived neural stem cells: From basic research to applications

    Institute of Scientific and Technical Information of China (English)

    Masahiro; Otsu; Takashi; Nakayama; Nobuo; Inoue

    2014-01-01

    Basic research on pluripotent stem cells is designed to enhance understanding of embryogenesis, whereas applied research is designed to develop novel therapies and prevent diseases. Attainment of these goals has been enhanced by the establishment of embryonic stem cell lines, the technological development of genomic reprogramming to generate induced-pluripotent stem cells, and improvements in in vitro techniques to manipulate stem cells. This review summarizes the techniques required to generate neural cells from pluripotent stem cells. In particular, this review describes current research applications of a simple neural differentiation method, the neural stem sphere method, which we developed.

  11. Basic research needs and priorities in solar energy. Volume II. Technology crosscuts for DOE

    Energy Technology Data Exchange (ETDEWEB)

    Jayadev, J S; Roessner, D [eds.

    1980-01-01

    Priorities for basic research important to the future developments of solar energy are idenified, described, and recommended. SERI surveyed more than 120 leading scientists who were engaged in or knowledgeable of solar-related research. The result is an amalgam of national scientific opinion representing the views of key researchers in relevant disciplines and of SERI staff members. The scientific disciplines included in the report are: chemistry, biology, materials sciences, engineering and mathematics, and the social and behavioral sciences. Each discipline is subdivided into two to five topical areas-and, within each topical area, research needs are described and ranked according to the priorities suggested in the survey. Three categories of priority were established: crucial, important, and needed. A narrative accompanying the description of research needs in each topical area discusses the importance of research in the area for solar energy development and presents the bases for the priority rankings recommended.

  12. Citation analysis may severely underestimate the impact of clinical research as compared to basic research

    OpenAIRE

    Eck, van, Pascal; Waltman, L.R.; Raan, van, A.F.J.; Klautz, R. J. M.; Peul, W C

    2012-01-01

    Background Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same medical field. Because of this, it is unclear to what extent citation-based bibliometric indicators allow for valid comparisons between research units active in different areas of medical research. Methodology A visualization methodology is introduced that rev...

  13. Mixed-methods research in pharmacy practice: basics and beyond (part 1).

    Science.gov (United States)

    Hadi, Muhammad Abdul; Alldred, David Phillip; Closs, S José; Briggs, Michelle

    2013-10-01

    This is the first of two papers which explore the use of mixed-methods research in pharmacy practice. In an era of evidence-based medicine and policy, high-quality research evidence is essential for the development of effective pharmacist-led services. Over the past decade, the use of mixed-methods research has become increasingly common in healthcare, although to date its use has been relatively limited in pharmacy practice research. In this article, the basic concepts of mixed-methods research including its definition, typologies and advantages in relation to pharmacy practice research are discussed. Mixed-methods research brings together qualitative and quantitative methodologies within a single study to answer or understand a research problem. There are a number of mixed-methods designs available, but the selection of an appropriate design must always be dictated by the research question. Importantly, mixed-methods research should not be seen as a 'tool' to collect qualitative and quantitative data, rather there should be some degree of 'integration' between the two data sets. If conducted appropriately, mixed-methods research has the potential to generate quality research evidence by combining strengths and overcoming the respective limitations of qualitative and quantitative methodologies.

  14. Recent advances in experimental basic research on graphene and graphene-based nanostructures

    Science.gov (United States)

    Hieu Nguyen, Van

    2016-06-01

    The present work is a review of the results achieved in the experimental basic research on following rapidly developing modern topics of nanoscience and nanotechnology related to graphene and graphene-based nanosystems: reduction of graphene oxide and investigation of physical properties of reduced graphene oxide; fabrication and investigation of graphene quantum dots; study of light emission from excited graphene; fabrication and investigation of graphene nanopores; preparation and investigation of graphene oxide-liquid crystals as well as aqueous graphene oxide dispersions. Besides presenting the scientific content of the above-mentioned five topics in detail, we briefly mention promising and interesting works, demonstrating that the area of basic research on graphene and graphene-based nanostructures is still being enlarged.

  15. Liver alveolar echinococcosis in China: Clinical aspect with relative basic research

    Institute of Scientific and Technical Information of China (English)

    Ci-Peng Jiang; McManus Don; Malcolm Jones

    2005-01-01

    This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.

  16. Quantum Well Infrared Photodetectors:the Basic Design and New Research Directions

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The basic design principles and parameters of GaAs/AlGaAs quantum well infrared photodetectors (QWIP) are reviewed.Furthermore new research directions,devices and applications suited for QWIPs are discussed.These include monolithic integration of QWIPs with GaAs based electronic and optoelectronic devices,high frequency and high speed QWIPs and applications,multicolor and multispectral detectors,and p-type QWIPs.

  17. Adapting the reactors Melusine and Siloe to the needs of basic research on exit beams

    International Nuclear Information System (INIS)

    This report shows how CENG swimming pools can be adapted to meet developing needs of basic research on exit beams. The experimental facilities offered are: two radial channels on Siloe and three radial and two tangential channels on Melusine. The use of various channels is outlined and modifications made to the channels described. Improvements involved the socks, protective shielding systems and collimator plugs and at Melusine, the installation of a heavy water tank. Some future trends are outlined

  18. Integrating Basic Research with Prevention/Intervention to Reduce Risky Substance Use among College Students

    Directory of Open Access Journals (Sweden)

    Danielle eDick

    2015-05-01

    Full Text Available Too often basic research on etiological processes that contribute to substance use outcomes is disconnected from efforts to develop prevention and intervention programming. Substance use on college campuses is an area of concern where translational efforts that bring together basic scientists and prevention/intervention practitioners have potential for high impact. We describe an effort at a large, public, urban university in the United States to bring together researchers across the campus with expertise in college behavioral health with university administration and health/wellness practitioners to address college student substance use and mental health. The project Spit for Science examines how genetic and environmental influences contribute to behavioral health outcomes across the college years. We argue that findings coming out of basic research can be used to develop more tailored prevention and intervention programming that incorporates both biologically and psychosocially influenced risk factors. Examples of personalized programming suggest this may be a fruitful way to advance the field and reduce risky substance use.

  19. Fourth annual workshop on management in basic and applied research environments

    Energy Technology Data Exchange (ETDEWEB)

    Bodnarczuk, M.W. [ed.

    1993-11-01

    The struggle to develop quality management concepts that ``map`` onto the cultural and work practices found in basic and applied research environments has been (for better or for worse) an attempt to differentiate basic and applied research from the nuclear industry. In the first (1990) edition of this ``Music Book`` proceedings, almost every laboratory that participated had a quality program that was traceable to, based on, influenced by, or in reaction to the nuclear quality standard ASME-NQA-1. This 1993 edition of the ``Music Book`` is very different in that almost every laboratory has developed a quality program that is based on, traceable to, or heavily influenced by DOE 5700.6C (Quality Assurance) and the DOE Standard; Implementation Guide for Quality Assurance Programs for Basic and Applied Research (DOE-ER-STD-6001-92). In order to construct a context for what follows and properly introduce the contents of this book, we want to briefly recount some of the highlights of the events that brought about this change, from the perspective of one who participated in the process.

  20. Science for Energy Technology: Strengthening the Link Between Basic Research and Industry

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-04-01

    The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding.Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a real and immediate impact on cost, reliability, and performance of technology, and ultimately a transformative impact on our economy. With its broad research base and unique scientific user facilities, the DOE Office of Basic Energy Sciences (BES) is ideally positioned to address these needs. BES has laid

  1. Entrepreneurial Behaviour of Researchers in a Basic Research Center the example of CERN

    CERN Document Server

    Sessano, Deborah

    2007-01-01

    The study aims to identify whether researchers' entrepreneurial behaviour changed after the introduction of a formal technology transfer policy (TTP) within CERN, the European Organization for Nuclear Research, a centre for fundamental research in particle physics. The chosen unit of analysis is the individual researcher with limited duration contract. An analysis of the background literature on entrepreneurial behaviour and factors affecting it was performed and parameters for analysis identified. A total of 103 responses to a specifically developed questionnaire were obtained and statistical analysis carried out to assess presence or absence of entrepreneurial behaviour and the factors affecting it. The theoretical framework was developed taking into account recognition by peers, network, character, prior knowledge, field of research and incentives and researchers and engineers were assessed for positive and negative correlations. One can conclude, in general, that the personnel shows a good degree of entre...

  2. Basic research and clinical application of optical molecular imaging in breast cancer

    International Nuclear Information System (INIS)

    As a rapidly developing biomedical imaging technology,in vivo optical molecular imaging has been widely applied in various research fields owing to its unique real-time, quantitative and noninvasive characteristics. The applications of in vivo optical imaging technology in the basic and clinical research of breast cancer were reviewed, including detection of distant metastasis,tumor apoptosis, cell cycle, hypoxia and angiogenesis, ER-mediated molecular pathway, breast cancer stem cells, early diagnosis, sentinel node biopsy, evaluation of drug efficacy and detection of human epidermal growth factor receptor-2 (HER-2) expression. They all seem to have a promising potential in in vivo optical molecular imaging. (authors)

  3. Magnet Science and Technology for Basic Research at the High Field Laboratory for Superconducting Materials

    Institute of Scientific and Technical Information of China (English)

    渡辺和雄

    2007-01-01

    Since the first practical cryocooled superconducting magnet using a GM-cryocooler and high temperature superconducting current leads has been demonstrated successfully at the High Field Laboratory for Superconducting Materials (HFLSM), various kinds of cryocooled superconducting magnets in fields up to 15 T have been used to provide access for new research areas in fields of magneto-science. Recently, the HFLSM has succeeded in demonstrating a cryocooed 18 T high temperature superconducting magnet and a high field cryocooled 27.5 T hybrid magnet. Cryocooled magnet technology and basic research using high field magnets at the HFLSM are introduced.

  4. Overview of basic and applied research on battery systems at Argonne

    Energy Technology Data Exchange (ETDEWEB)

    Nevitt, M. V.

    1979-01-01

    The need for a basic understanding of the ion transport and related effects that are observed under the unique physical and electrochemical conditions occurring in high-temperature, high-performance batteries is pointed out. Such effects include those that are typical of transport in bulk materials such as liquid and solid electrolytes and the less well understood effects observed in migration in and across the interfacial zones existing around electrodes. The basic and applied studies at Argonne National Laboratory, centered in part around the development of a Li(alloy)/iron sulfide battery system for energy storage, are briefly described as an example of the way that such an understanding is being sought by coordinated interdisciplinary research. 3 figures.

  5. Defense, basic, and industrial research at the Los Alamos Neutron Science Center: Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Longshore, A.; Salgado, K. [comps.

    1995-10-01

    The Workshop on Defense, Basic, and Industrial Research at the Los Alamos Neutron Science Center gathered scientists from Department of Energy national laboratories, other federal institutions, universities, and industry to discuss the use of neutrons in science-based stockpile stewardship, The workshop began with presentations by government officials, senior representatives from the three weapons laboratories, and scientific opinion leaders. Workshop participants then met in breakout sessions on the following topics: materials science and engineering; polymers, complex fluids, and biomaterials; fundamental neutron physics; applied nuclear physics; condensed matter physics and chemistry; and nuclear weapons research. They concluded that neutrons can play an essential role in science-based stockpile stewardship and that there is overlap and synergy between defense and other uses of neutrons in basic, applied, and industrial research from which defense and civilian research can benefit. This proceedings is a collection of talks and papers from the plenary, technical, and breakout session presentations. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  6. Analysis of Research in Physical Activities of Slovenian Basic School Children in Recent Years

    Directory of Open Access Journals (Sweden)

    Klavdija Strniša

    2015-06-01

    Full Text Available Nowadays, physical activity is an extremely important segment of a healthy lifestyle not only for children but also for adults. Technological advances allow us to reach our goals with much less physical effort than was required of the individual in the past. Additionally, the fast pace of life and an increasingly sedentary lifestyle also contribute to reduced physical activity among the population. Analysis of published scientific articles in the field of physical activity among basic school students includes 15 research studies. They were included regardless of the origin of the publication and citation frequency. It can be seen that the most common segment of research in children’s physical activity is the gender perspective. Researchers are further interested in the effects of age, educational success, BMI, place of residence, frequency and time spent in physical activity, education and physical activity of parents, as well as the level of organization (organized / unorganized activity. Therefore it can be concluded that children’s physical activities are influenced by external and internal factors. Analysis of published research has shown that physical activity depends upon many internal and external factors. A higher level of physical activity is often detected with boys and children in urban areas, compared to rural ones. Physically active parents have physically more active children. A higher proportion of interviewed basic school students was found to participate in organized forms of exercise in comparison to the unorganized ones.

  7. Historical chronology of basic and clinical research in diabetic nephropathy and contributions of Japanese scientists.

    Science.gov (United States)

    Wada, Jun; Makino, Hirofumi

    2009-10-01

    The most problematic issue in clinical nephrology worldwide is the relentless and progressive increase in patients with end-stage renal disease (ESRD). Diabetic nephropathy has considerable impact on society in the areas of public health and social economy; many scientists are involved in research for the elucidation of the pathogenesis of diabetic nephropathy and for the prevention and cure of the disease. In contrast, diabetic nephropathy was a neglected or ignored disease in the historical era, and few dedicated physicians recognized the disease process of diabetic nephropathy. In this review, we look back on the history of basic and clinical research on diabetic nephropathy and survey the recent progress of the research, especially focusing on the contribution of Japanese scientists. PMID:19363645

  8. Present status of the innovative basic research on high-temperature engineering using the HTTR

    International Nuclear Information System (INIS)

    The high-temperature engineering test reactor (HTTR) of JAERI aims at establishment and upgrading the HTGR technologies as well as the innovative basic research in the field of high-temperature engineering. It is now under commissioning tests and will soon achieve the rated power of 30 I/W. This paper presents a brief overview concerning the innovative basic research in the following fields: - New materials development of high-temperature oxide superconductors (HTSC), high performance silicon carbide (SIC) semiconductor, and heat-resistant ceramic composite materials. - High-temperature radiation chemistry research on poly-silane decomposition into SiC fibres, and high-temperature radiolysis of heavy oils and plastics, as well as in situ measurement of property changes of solid tritium breeding materials under irradiation. - High-temperature in-core instrumentation development of a heat- and radiation-resistant optical fibre system and of devices for monitoring neutron and gamma-ray spectra. JAERI is preparing for the first HTTR irradiation in 2003 and will then proceed to the international collaboration phase on. high-temperature irradiation test for development of the new materials in the field of high-temperature engineering. (authors)

  9. Low-cost USB interface for operant research using Arduino and Visual Basic.

    Science.gov (United States)

    Escobar, Rogelio; Pérez-Herrera, Carlos A

    2015-03-01

    This note describes the design of a low-cost interface using Arduino microcontroller boards and Visual Basic programming for operant conditioning research. The board executes one program in Arduino programming language that polls the state of the inputs and generates outputs in an operant chamber. This program communicates through a USB port with another program written in Visual Basic 2010 Express Edition running on a laptop, desktop, netbook computer, or even a tablet equipped with Windows operating system. The Visual Basic program controls schedules of reinforcement and records real-time data. A single Arduino board can be used to control a total of 52 inputs/output lines, and multiple Arduino boards can be used to control multiple operant chambers. An external power supply and a series of micro relays are required to control 28-V DC devices commonly used in operant chambers. Instructions for downloading and using the programs to generate simple and concurrent schedules of reinforcement are provided. Testing suggests that the interface is reliable, accurate, and could serve as an inexpensive alternative to commercial equipment.

  10. [Between bench and bedside: examples of clinically oriented basic surgery research].

    Science.gov (United States)

    Hotz, H G; Foitzik, T; Runkel, N; Buhr, H J

    1997-01-01

    Animal experimental studies are an effective modality for testing new therapeutic strategies, provided that the animal model and the study protocol simulate the clinical situation. This is exemplified by various animal experimental studies on the therapy of infectious complications in acute necrotizing pancreatitis that were performed preliminary or supplementary to clinical studies. The results show that basic surgical research with close clinical orientation can be usefully and fruitfully combined with clinical studies and enables the academically active young surgeon to overcome the dualism between laboratory work and clinical practice.

  11. Science for Energy Technology: Strengthening the Link between Basic Research and Industry

    Energy Technology Data Exchange (ETDEWEB)

    Hemminger, John C [University of California Irvine

    2010-08-01

    This Basic Energy Sciences Advisory Committee (BESAC) report summarizes the results of a Workshop on Science for Energy Technology on January 18-21, 2010, to identify the scientific priority research directions needed to address the roadblocks and accelerate the innovation of clean energy technologies. The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding. Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a

  12. Exploratory of society

    Science.gov (United States)

    Cederman, L.-E.; Conte, R.; Helbing, D.; Nowak, A.; Schweitzer, F.; Vespignani, A.

    2012-11-01

    A huge flow of quantitative social, demographic and behavioral data is becoming available that traces the activities and interactions of individuals, social patterns, transportation infrastructures and travel fluxes. This has caused, together with innovative computational techniques and methods for modeling social actions in hybrid (natural and artificial) societies, a qualitative change in the ways we model socio-technical systems. For the first time, society can be studied in a comprehensive fashion that addresses social and behavioral complexity. In other words we are in the position to envision the development of large data and computational cyber infrastructure defining an exploratory of society that provides quantitative anticipatory, explanatory and scenario analysis capabilities ranging from emerging infectious disease to conflict and crime surges. The goal of the exploratory of society is to provide the basic infrastructure embedding the framework of tools and knowledge needed for the design of forecast/anticipatory/crisis management approaches to socio technical systems, supporting future decision making procedures by accelerating the scientific cycle that goes from data generation to predictions.

  13. Proceedings of the 109th basic science seminar on research for quantum radiation measurement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    In the field of radiation measurement in next century, one of the main themes for researchers will be to develop new radiation detection techniques based on quantum effects. Thus three research projects for development of new neutron detection method using He-Ne laser cells, radiation-resistant optical fibers, and superconducting tunnel junction radiation detectors have been started five years before in our research group for quantum radiation measurement of the advanced science research center (ASRC) of JAERI. The joint workshop `Research for Quantum Radiation Measurement` was held as one of basic science seminars in ASRC on 19-20th of January 1998 on the occasion of the ending of the projects. There were many presentations concerning the above three themes and the participants had a good opportunity to exchange relating research information. This proceedings includes 13 papers of the presentations. It is not only useful to know the present status of advanced study but also very suggestive to see the direction and evolution of `radiation detection techniques based on quantum effects` in the future. (J.P.N.)

  14. Basic research needs and priorities in solar energy. Volume I. Executive summary. Technology crosscuts for DOE

    Energy Technology Data Exchange (ETDEWEB)

    Jayadev, T S; Roessner, D [eds.

    1980-01-01

    This report identifies, describes, and recommends priorities for basic research important to the future development of solar energy. In response to a request from the US Department of Energy, SERI surveyed more than 120 leading scientists who were engaged in or knowledgeable of solar-related research. SERI scientists relied heavily on the opinions of scientists polled, but weighted their own recommendations and opinions equally. The result is an amalgam of national scientific opinion representing the views of key researchers in relevant disciplines and of SERI staff members. The Scientific disciplines included in the report are: chemistry, biology, materials sciences, engineering and mathematics, and the social and behavioral sciences. Each discipline is subdivided into two to five topical areas and, wintin each topical area, research needs are described and ranked according to the priorities suggested in the survey. Three categories of priority were established: Crucial, important, and needed. A narrative accompanying the descripton of research needs in each topical area discusses the importance of research in the area for solar energy development and presents the bases for the priority rankings recommended.

  15. Materials Issues in Advanced Nuclear Systems: Executive Summary of DOE Basic Research Needs Workshop, 'Basic Research Needs for Advanced Nuclear Energy Systems'

    International Nuclear Information System (INIS)

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  16. Large Scale Computing and Storage Requirements for Basic Energy Sciences Research

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, Richard; Wasserman, Harvey

    2011-03-31

    The National Energy Research Scientific Computing Center (NERSC) is the leading scientific computing facility supporting research within the Department of Energy's Office of Science. NERSC provides high-performance computing (HPC) resources to approximately 4,000 researchers working on about 400 projects. In addition to hosting large-scale computing facilities, NERSC provides the support and expertise scientists need to effectively and efficiently use HPC systems. In February 2010, NERSC, DOE's Office of Advanced Scientific Computing Research (ASCR) and DOE's Office of Basic Energy Sciences (BES) held a workshop to characterize HPC requirements for BES research through 2013. The workshop was part of NERSC's legacy of anticipating users future needs and deploying the necessary resources to meet these demands. Workshop participants reached a consensus on several key findings, in addition to achieving the workshop's goal of collecting and characterizing computing requirements. The key requirements for scientists conducting research in BES are: (1) Larger allocations of computational resources; (2) Continued support for standard application software packages; (3) Adequate job turnaround time and throughput; and (4) Guidance and support for using future computer architectures. This report expands upon these key points and presents others. Several 'case studies' are included as significant representative samples of the needs of science teams within BES. Research teams scientific goals, computational methods of solution, current and 2013 computing requirements, and special software and support needs are summarized in these case studies. Also included are researchers strategies for computing in the highly parallel, 'multi-core' environment that is expected to dominate HPC architectures over the next few years. NERSC has strategic plans and initiatives already underway that address key workshop findings. This report includes a

  17. Human Induced Pluripotent Stem Cells from Basic Research to Potential Clinical Applications in Cancer

    Directory of Open Access Journals (Sweden)

    Teresa de Souza Fernandez

    2013-01-01

    Full Text Available The human induced pluripotent stem cells (hiPSCs are derived from a direct reprogramming of human somatic cells to a pluripotent stage through ectopic expression of specific transcription factors. These cells have two important properties, which are the self-renewal capacity and the ability to differentiate into any cell type of the human body. So, the discovery of hiPSCs opens new opportunities in biomedical sciences, since these cells may be useful for understanding the mechanisms of diseases in the production of new diseases models, in drug development/drug toxicity tests, gene therapies, and cell replacement therapies. However, the hiPSCs technology has limitations including the potential for the development of genetic and epigenetic abnormalities leading to tumorigenicity. Nowadays, basic research in the hiPSCs field has made progress in the application of new strategies with the aim to enable an efficient production of high-quality of hiPSCs for safety and efficacy, necessary to the future application for clinical practice. In this review, we show the recent advances in hiPSCs’ basic research and some potential clinical applications focusing on cancer. We also present the importance of the use of statistical methods to evaluate the possible validation for the hiPSCs for future therapeutic use toward personalized cell therapies.

  18. Genome elimination: translating basic research into a future tool for plant breeding.

    Directory of Open Access Journals (Sweden)

    Luca Comai

    2014-06-01

    Full Text Available During the course of our history, humankind has been through different periods of agricultural improvement aimed at enhancing our food supply and the performance of food crops. In recent years, it has become apparent that future crop improvement efforts will require new approaches to address the local challenges of farmers while empowering discovery across industry and academia. New plant breeding approaches are needed to meet this challenge to help feed a growing world population. Here I discuss how a basic research discovery is being translated into a potential future tool for plant breeding, and share the story of researcher Simon Chan, who recognized the potential application of this new approach--genome elimination--for the breeding of staple food crops in Africa and South America.

  19. Basic Research Needs for Solar Energy Utilization: report of the Basic Energy Sciences Workshop on Solar Energy Utilization, April 18-21, 2005

    OpenAIRE

    Lewis, Nathan S.; Crabtree, George

    2005-01-01

    This report of the Basic Energy Sciences Workshop on Solar Energy Utilization identifies the key scientific challenges and research directions that will enable efficient and economic use of the solar resource to provide a significant fraction of global primary energy by the mid 21st century. The report reflects the collective output of the workshop attendees, which included 200 scientists representing academia, national laboratories, and industry in the United States and abroad, and the U.S. ...

  20. Pharmacy Education Reaction to Presentations on Bridging the Gap Between the Basic Sciences and Clinical Practice: Teaching, Research, and Service.

    Science.gov (United States)

    Doluisio, James T.

    1980-01-01

    Issues in the conflict between clinical practice and basic research in pharmacy are reviewed: professional associations' role, curriculum needs and traditions, internal strains and diversity in the profession, computer use, scholarly work of faculty, using the medical profession as a model, and misperceptions of what clinical and basic sciences…

  1. Increasing the public health potential of basic research and the scientist satisfaction. An international survey of bioscientists.

    Science.gov (United States)

    Scita, Giorgio; Sorrentino, Carmen; Boggio, Andrea; Hemenway, David; Ballabeni, Andrea

    2016-01-01

    Basic scientific research generates knowledge that has intrinsic value which is independent of future applications. Basic research may also lead to practical benefits, such as a new drug or diagnostic method.  Building on our previous study of basic biomedical and biological researchers at Harvard, we present findings from a new survey of similar scientists from three countries.  This survey asked about the scientists' motivations, goals and perspectives along with their attitudes concerning  policies designed to increase both the practical (i.e. public health) benefits of basic research as well as their own personal satisfaction. Close to 900 basic investigators responded to the survey; results corroborate the main findings from the previous survey of Harvard scientists.  In addition, we find that most bioscientists disfavor present policies that require a discussion of the public health potential of their proposals in grants but generally favor softer policies aimed at increasing the quality of work and the potential practical benefits of basic research. In particular, bioscientists are generally supportive of those policies entailing the organization of more meetings between scientists and the general public, the organization of more academic discussion about the role of scientists in the society, and the implementation of a "basic bibliography" for each new approved drug.

  2. Increasing the public health potential of basic research and the scientist satisfaction. An international survey of bioscientists.

    Science.gov (United States)

    Scita, Giorgio; Sorrentino, Carmen; Boggio, Andrea; Hemenway, David; Ballabeni, Andrea

    2016-01-01

    Basic scientific research generates knowledge that has intrinsic value which is independent of future applications. Basic research may also lead to practical benefits, such as a new drug or diagnostic method.  Building on our previous study of basic biomedical and biological researchers at Harvard, we present findings from a new survey of similar scientists from three countries.  This survey asked about the scientists' motivations, goals and perspectives along with their attitudes concerning  policies designed to increase both the practical (i.e. public health) benefits of basic research as well as their own personal satisfaction. Close to 900 basic investigators responded to the survey; results corroborate the main findings from the previous survey of Harvard scientists.  In addition, we find that most bioscientists disfavor present policies that require a discussion of the public health potential of their proposals in grants but generally favor softer policies aimed at increasing the quality of work and the potential practical benefits of basic research. In particular, bioscientists are generally supportive of those policies entailing the organization of more meetings between scientists and the general public, the organization of more academic discussion about the role of scientists in the society, and the implementation of a "basic bibliography" for each new approved drug. PMID:27347372

  3. INTERNATIONAL MARKETING RESEARCH: BASIC CHARACTERISTICS AND THEIR IMPORTANCE FOR ECONOMY IN TRANSITION

    Directory of Open Access Journals (Sweden)

    Vedran Stanetić

    2012-01-01

    Full Text Available This paper aims to highlight thebasic characteristics of international marketingresearches and their importance to the economiesin transition. The idea, which the author has alwayshad in mind when he wrote the following lines, ishow to describe and explain in concise andaffordable way the basic principles governingresearch in an international environment, as wellas the possibility of their fastest and easiestimplementation, always emphasizing the differencesbetween international and national, local, market.Unlike the more developed countries where theconcept of marketing and marketing research isimplied, in less developed countries and countriesin transition, it is not the case. The latest GlobalCompetitiveness Report by World Economic Forumfor 2011-2012 indicates a forementionedconclusion. Companies that adopt marketing as aconcept of their development, the internationalmarket as the focus of their interest and which usemarketing research in implementation of theirbusiness objectives, have a greater chance ofprosperity in economically uncertain times ahead.The paper is based on the compilation of mostsignificant marketing and research guidelines fromthe literature that deal with the aforementionedtopics, as well as the analysis of the role andimportance of international marketing research intransition economies, especially in view of BiH,which is based on the findings of the abovementioned report of the World Economic Forum.

  4. Incorporation of basic research and service components in a field environmental geochemistry course

    Science.gov (United States)

    Senko, J.

    2015-12-01

    "Application-based service learning" (ABSL) refers to an approach to formal course instruction that integrates service and research components into the course. An ABSL approach was employed in a field-based environmental chemistry course, whose goal was to evaluate and monitor the aqueous geochemistry of coal mine-derived acid mine drainage (AMD) in the Appalachia basin. In this course, students conducted literature reviews on the geochemistry and environmental impacts of AMD, participated in a field sampling campaign of several AMD treatment systems, and conducted chemical analyses of the samples that they retrieved. The remainder of the course was dedicated to "lab meetings," during which data was analyzed, conclusions were drawn from the data, and a manuscript was drafted that described the findings of the field analyses, and made recommendations regarding the performance of the AMD treatment systems. The service component of the course focused on socioeconomic impacts of coal mining and the Appalachian region, with the final manuscript distributed to AMD treatment practitioners and state regulatory agencies. A comparison of pre- and post-course questionnaires that included Likert scale questions revealed that students' attitudes toward basic research improved over the period or the course. Based on the questionnaires attitudes toward service diminished, but "open-ended" questionnaires indicated an improved attitude toward both research and service, with an emphasis on the benefits of research that serves the community. Ultimately, we hope to develop approaches to compare the effectiveness of ABSL-based across disciplines.

  5. Fundamentos, Orientaciones, Areas Basicas y Procedimientos para la Investigacion Educativa (Bases, Guidelines, Basic Areas, and Procedures for Educational Research).

    Science.gov (United States)

    Ministerio de Educacion Nacional, Bogota (Colombia). Instituto Colombiano de Pedagogia.

    This document establishes the bases, general guidelines, basic areas, and procedures for educational research conducted in Colombia. The philosophy underlying research objectives is explained. There is special interest in social research concerning the condition of man and of the social groups that will be the targets of education, and in research…

  6. The basic research on the CDA initiation phase for a metallic fuel FBR

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Go; Hirakawa, Naohiro [Tohoku Univ., Sendai (Japan); Kawada, Ken-ichi; Niwa, Hazime

    1998-03-01

    A metallic fuel with novel design has received great deal of interest recently as an option of advanced fuel to be substituted MOX fuel, however, the behavior at the transient has not been studied in many aspects. Therefore, for the purpose to show the basic tendency of the behavior and released energy at CDA (core disruptive accident) for a metallic fuel FBR and to prepare the basic knowledge for consideration of the adoption of the advanced fuel, Tohoku University and Power Reactor and Nuclear Fuel Development Corporation have made a joint research entitled. (1) Target and Results of analysis: The accident initiator considered is a LOF accident with ATWS. The LOF analysis was performed for a metallic fuel 600 MWe homogeneous two region core at the beginning of cycle, both for an ordinary metallic fuel core and for a metallic fuel core with ZrH pins. It was necessary mainly to change the constants of input parameters to apply the code for the analysis of a metallic fueled reactor. These changes were made by assuming appropriate models. Basic LOF cases and all blackout case that assumed using electromagnetic pumps were analyzed. The results show that the basic LOF cases for a metallic fuel core and all the cases for a metallic fuel core with ZrH pins could be avoided to become prompt-critical, and mildly transfer to the transient phase. (2) Improvement of CDA initiation phase analysis code: At present, it is difficult for the code to adapt to the large material movement to in the core at the transient. Therefore, the nuclear calculation model in the code was improved by using the adiabatic space dependent kinetics. The results of a sample case, that is a metallic fueled core at the beginning of cycle, show this improvement is appropriate. (3) Conclusion: The behavior at CDA of a metallic fueled core of a fast reactor was analyzed using the CDA initiation phase analysis code and the knowledge of the important characteristics at the CDA initiation phase was obtained

  7. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    Science.gov (United States)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A. L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-12-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9-14% Cr ferritic-martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical-chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α‧ unmixing.

  8. Research and Education in Basic Space Science The Approach Pursued in the UN/ESA Workshops

    CERN Document Server

    Al-Naimiy, H M K; Chamcham, K; de Alwis, S P; De Carias, M C P; Haubold, H J; Boggino, A E T

    2000-01-01

    Since 1990, the United Nations in cooperation with the European Space Agencyis holding annually a workshop on basic space science for the benefit of theworldwide development of astronomy. These workshops have been held in countriesof Asia and the Pacific (India, Sri Lanka), Latin America and the Caribbean(Costa Rica, Colombia, Honduras), Africa (Nigeria), Western Asia (Egypt,Jordan), and Europe (Germany, France). Additional to the scientific benefits ofthe workshops and the strengthening of international cooperation, the workshopslead to the establishment of astronomical telescope facilities in Colombia,Egypt, Honduras, Jordan, Morocco, Paraguay, Peru, Philippines, Sri Lanka, andUruguay. The annual UN/ESA Workshops continue to pursue an agenda to networkthese astronomical telescope facilities through similar research and educationprogrammes. Teaching material and hands-on astrophysics material has beendeveloped for the operation of such astronomical telescope facilities in anuniversity environment.

  9. Quantitative High Resolution Transmission Electron Microscopy (HRTEM): a novel approach towards application oriented basic research

    International Nuclear Information System (INIS)

    This paper reviews recent developments of microscopic methods that base on a quantitative analysis of electron micrographs to access subsurface systems at the atomic scale. It focuses on non-equilibrium diffusion processes that are observed in nano structured MBE grown materials if a low growth temperature was used and on local deviations from a stoichiometric composition of materials. As examples we investigate Ga As/Al As and Si/Ge Si heterostructures and Ga N single crystals. The purpose of the research is twofold. On the one hand it helps understanding physical processes at the atomic scale. On the other hand we can use the results to link basic physical knowledge with the performance of semiconductor devices made from nano structured materials. (author). 28 refs., 15 figs

  10. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    International Nuclear Information System (INIS)

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9–14% Cr ferritic–martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical–chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α′ unmixing

  11. Exploratory Analysis in Learning Analytics

    Science.gov (United States)

    Gibson, David; de Freitas, Sara

    2016-01-01

    This article summarizes the methods, observations, challenges and implications for exploratory analysis drawn from two learning analytics research projects. The cases include an analysis of a games-based virtual performance assessment and an analysis of data from 52,000 students over a 5-year period at a large Australian university. The complex…

  12. Systematic Review: The Association and Impact of Financial Conflicts of Interest in Basic Science Research

    Science.gov (United States)

    Bennett, Charles L.; Boyle, Simone N.; Kuykendal, Adam; Fisher, Matthew J.; Samaras, Athena T.; Barnato, Sara E.; Wagner, Robin L.; Goldstein, Carolyn E.; Tallman, Jacob; Munshi, Hidayatullah G.; Lai, Stephen Y.; Henke, Michael

    2009-01-01

    Background No prior study has evaluated financial relationships of investigators with pharmaceutical manufacturers for basic science. An example of the importance and impact of such relationships is in the evaluation of erythropoietin receptors’(EpoRs) effects on cancer cell lines, since studies have reported increased mortality when cancer patients receive erythropoiesis stimulating agents (ESAs). Purpose To assess the disclosed association that exist between pharmaceutical industry support and EpoRs effects on solid cancer cell lines. Data Sources MEDLINE and EMBASE (1988- July 2008) and two EpoR conferences sponsored by the National Institutes of Health. Study Selection All publications investigating EpoRs that met inclusion criteria were identified and included. Data Extraction Data were extracted on detection of EpoRs, presence of erythropoietin-induced signaling events, presence of erythropoietin-induced changes in cellular function, nature of qualitative conclusions, and sources of funding for all 74 studies. Data Synthesis In comparison to studies of academic investigators with no disclosed funding support from ESA manufacturers (n=64), the studies from academic investigators with funding support from ESA manufacturers (n= 7) and the laboratories directed by investigators employed by ESA manufacturers (n=3) were both less likely to identify: EpoR presence on solid tumor cells; erythropoietin-induced signaling events; erythropoietin-induced changes in cellular function; and less likely to conclude that their research had identified potentially harmful effects of erythropoietin on cancer cells. Additionally, presentations from industry-based investigator teams at NIH conferences were less likely to report EpoRs on cancer cell lines, downstream effects of erythropoietin, and cell proliferation and migration effects following EpoR administration. Conclusion Financial conflicts of interest impact the outcomes and presentation of basic science research data as

  13. It Started in a GE Freezer: Basic Precipitation Research Triggers the Business of Weather Modification

    Science.gov (United States)

    Harper, K.

    2015-12-01

    At the end of World War II, Nobel Prize-winning chemist Irving Langmuir and his team at the General Electric Research Laboratory in Schenectady, New York, were doing advanced research on cloaking smokes and aircraft icing for the US military. Trying to determine why some clouds precipitated while others did not, Langmuir concluded that non-precipitating clouds were lacking "ice nuclei" that would gather up cloud droplets until they became large enough to fall out of the cloud. If they could find an artificial substitute, it would be possible to modify clouds and the weather. Dry ice particles did the trick, military funding followed, and cloud busting commenced. But a handful of entrepreneurial meteorologists saw a different purpose: enhancing precipitation and preventing hail damage. The commercialization of weather modification was underway, with cloud seeding enhancing rainfall east of the Cascades, in the Desert Southwest, and even in the watersheds serving New York City. Hail busting took off in the Dakotas, and snowpack enhancement got a boost in Montana. Basic cloud physics research very quickly became commercial weather modification, fulfilling a postwar desire to use science and technology to control nature and creating an opening for meteorologists to provide a variety of specialized services to businesses whose profits depend on the weather.

  14. A Beginner’s Guide to Factor Analysis: Focusing on Exploratory Factor Analysis

    Directory of Open Access Journals (Sweden)

    An Gie Yong

    2013-10-01

    Full Text Available The following paper discusses exploratory factor analysis and gives an overview of the statistical technique and how it is used in various research designs and applications. A basic outline of how the technique works and its criteria, including its main assumptions are discussed as well as when it should be used. Mathematical theories are explored to enlighten students on how exploratory factor analysis works, an example of how to run an exploratory factor analysis on SPSS is given, and finally a section on how to write up the results is provided. This will allow readers to develop a better understanding of when to employ factor analysis and how to interpret the tables and graphs in the output.

  15. Brain Basics

    Medline Plus

    Full Text Available ... Trials — Participants Statistics Help for Mental Illnesses Outreach Research Priorities Funding Labs at NIMH News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The ...

  16. Selected works of basic research on the physics and technology of accelerator driven clean nuclear power system

    International Nuclear Information System (INIS)

    38 theses are presented in this selected works of basic research on the physics and technology of accelerator driven clean nuclear power system. It includes reactor physics and experiment, accelerators physics and technology, nuclear physics, material research and partitioning. 13 abstracts, which has been presented on magazines home and abroad, are collected in the appendix

  17. The NUTRA-SNACKS project: basic research and biotechnological programs on nutraceutics.

    Science.gov (United States)

    Rea, Giuseppina; Antonacci, Amina; Lambreva, Maya; Margonelli, Andrea; Ambrosi, Cecilia; Giardi, Maria Teresa

    2010-01-01

    The Nutra-Snacks project aims at creating novel high quality ready-to-eat foods with functional activity, useful for promoting public health. The team is composed of seven research institutes and three SMEs from different countries whose activities span from basic to applied research providing the right technological transfer to small and medium industries involved in the novel food production chain. Strategic objectives include the application of plant cell and in vitro culture systems to create very large amounts of high-value plant secondary metabolites with recognized anticancer, antilipidemic, anticholesterol, antimicrobial, antiviral, antihypertensive and anti-inflammatory properties and to include them in specific food products. To this end, the screening of a vast number of working organisms capable of accumulating the desired compounds and the characterization of their expression profiles represent fundamental steps in the research program. The information allows the identification of plant species hyper-producing metabolites and selection of those metabolites capable of specifically counteracting the oxidative stress that underlies the development of important pathologies and diseases. In addition, devising safe metabolite extraction procedures is also crucial in order to provide nutraceutical-enriched extracts compatible with human health. New biotechnological approaches are also undertaken including the exploitation of photosynthetic algal strains in bio-farms to enhance the synthesis ofantioxidant compounds and the design of novel bioreactors for small and large scale biomass production. Further outstanding objectives include the development of (i) safety and quality control protocols (ii) biosensor techniques for the analysis of the emerging ready-to-eat food and (iii) a contribution to define a standard for new regulations on nutraceutics.

  18. The Emergence of Inclusive Exploratory Talk in Primary Students' Peer Interaction

    Science.gov (United States)

    Rajala, Antti; Hilppo, Jaakko; Lipponen, Lasse

    2012-01-01

    In this study, we examine a prominent type of classroom talk, exploratory talk, in primary school peer interactions. Exploratory talk has been shown to be productive in facilitating problem solving and fostering school achievement. However, within the growing body of research concerning exploratory talk, the relation between exploratory talk and…

  19. Large-scale User Facility Imaging and Scattering Techniques to Facilitate Basic Medical Research

    International Nuclear Information System (INIS)

    Conceptually, modern medical imaging can be traced back to the late 1960's and into the early 1970's with the advent of computed tomography . This pioneering work was done by 1979 Nobel Prize winners Godfrey Hounsfield and Allan McLeod Cormack which evolved into the first prototype Computed Tomography (CT) scanner in 1971 and became commercially available in 1972. Unique to the CT scanner was the ability to utilize X-ray projections taken at regular angular increments from which reconstructed three-dimensional (3D) images could be produced. It is interesting to note that the mathematics to realize tomographic images was developed in 1917 by the Austrian mathematician Johann Radon who produced the mathematical relationships to derive 3D images from projections - known today as the Radon Transform . The confluence of newly advancing technologies, particularly in the areas of detectors, X-ray tubes, and computers combined with the earlier derived mathematical concepts ushered in a new era in diagnostic medicine via medical imaging (Beckmann, 2006). Occurring separately but at a similar time as the development of the CT scanner were efforts at the national level within the United States to produce user facilities to support scientific discovery based upon experimentation. Basic Energy Sciences within the United States Department of Energy currently supports 9 major user facilities along with 5 nanoscale science research centers dedicated to measurement sciences and experimental techniques supporting a very broad range of scientific disciplines. Tracing back the active user facilities, the Stanford Synchrotron Radiation Lightsource (SSRL) a SLAC National Accelerator Laboratory was built in 1974 and it was realized that its intense x-ray beam could be used to study protein molecular structure. The National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory was commissioned in 1982 and currently has 60 x-ray beamlines optimized for a number of different

  20. Missional Imaginations for Theological Education: Mixed Model, Exploratory, Action-Oriented Research Mapping the Theological Identity and Organizational Readiness for Change of Five Theological School Systems in the United States Originating after 1945

    Science.gov (United States)

    Small, Kyle J. A.

    2009-01-01

    This dissertation explores the formal theologies and organizational readiness for change with a view towards adopting missional prototypes for theological education across a school's (system's) tradition, curriculum, and structure. The research assessed five theological schools in the United States through an exploratory, action-oriented,…

  1. Research investigations in oil shale, tar sand, coal research, advanced exploratory process technology, and advanced fuels research: Volume 1 -- Base program. Final report, October 1986--September 1993

    Energy Technology Data Exchange (ETDEWEB)

    Smith, V.E.

    1994-05-01

    Numerous studies have been conducted in five principal areas: oil shale, tar sand, underground coal gasification, advanced process technology, and advanced fuels research. In subsequent years, underground coal gasification was broadened to be coal research, under which several research activities were conducted that related to coal processing. The most significant change occurred in 1989 when the agreement was redefined as a Base Program and a Jointly Sponsored Research Program (JSRP). Investigations were conducted under the Base Program to determine the physical and chemical properties of materials suitable for conversion to liquid and gaseous fuels, to test and evaluate processes and innovative concepts for such conversions, to monitor and determine environmental impacts related to development of commercial-sized operations, and to evaluate methods for mitigation of potential environmental impacts. This report is divided into two volumes: Volume 1 consists of 28 summaries that describe the principal research efforts conducted under the Base Program in five topic areas. Volume 2 describes tasks performed within the JSRP. Research conducted under this agreement has resulted in technology transfer of a variety of energy-related research information. A listing of related publications and presentations is given at the end of each research topic summary. More specific and detailed information is provided in the topical reports referenced in the related publications listings.

  2. Marine survey techniques: A prerequisite for exploratory fishing

    Digital Repository Service at National Institute of Oceanography (India)

    Pathak, M.C.; Kotnala, K.L.

    which in turn will be useful to study the morphology of the survey area. The topographic configuration, (bathymetry chart) and accurate positioning are the basic and useful tools for the exploratory fishing....

  3. Cytokine-induced killer (CIK) cells:from basic research to clinical translation

    Institute of Scientific and Technical Information of China (English)

    Yelei Guo; Weidong Han

    2015-01-01

    The accumulation of basic researches and clinical studies related to cytokine-induced killer (CIK) cells has confirmed their safety and feasibility in treating malignant diseases. This review summarizes the available published literature related to the biological characteristics and clinical applications of CIK cells in recent years. A number of clinical trials with CIK cells have been implemented during the progressive phases of cancer, presenting potential widespread applications of CIK cells for the future. Furthermore, this review briefly compares clinical applications of CIK cells with those of other adoptive immunotherapeutic cells. However, at present, there are no uniform criteria or large-scale preparations of CIK cells. The overall clinical response is difficult to evaluate because of the use of autologous CIK cells. Based on these observations, several suggestions regarding uniform criteria and universal sources for CIK cell preparations and the use of CIK cells either combined with chemotherapy or alone as a primary strategy are briefly proposed in this review. Large-scale, controlled, grouped, and multi-center clinical trials on CIK cell-based immunotherapy should be conducted under strict supervision. These interventions might help to improve future clinical applications and increase the clinical curative effects of CIK cells for a broad range of malignancies in the future.

  4. Observing ben wyckoff: from basic research to programmed instruction and social issues.

    Science.gov (United States)

    Escobar, Rogelio; Lattal, Kennon A

    2011-01-01

    L. Benjamin Wyckoff's seminal contributions to both psychological theory and application are the subject of this review. Wyckoff started his academic career as a graduate student at Indiana University, where he developed the observing-response procedure under the guidance of B. F. Skinner and C. J. Burke. At the University of Wisconsin-Madison, Wyckoff refined his mathematical theory of secondary reinforcement. This theory was the impetus for his creation of an electronic simulation of a rat running a T maze, one of the first "computer models" of learning. Wyckoff next went to Emory University, leaving there to help create two of the most successful companies dedicated to the advancement of programmed instruction and teaching machines: Teaching Machines, Inc. and the Human Development Institute. Wyckoff's involvement in these companies epitomizes the application of basic behavior-analytic principles in the development of technology to improve education and human relationships. The emergent picture of Wyckoff is that of a man who, through his research, professional work in educational applications of behavioral principles, and active involvement in the civil rights movement of the 1960s, was strongly committed to applying behavioral science to positively influence human behavior change.

  5. Research on the Basic Computer Application Learning Strategies in Rural Middle School

    Institute of Scientific and Technical Information of China (English)

    WEI xia

    2014-01-01

    Fewer scholars in China fixed on the basic computer application learning strategies for rural students,in this paper, I want to discuss them for those students, and give them some helpful strategies to promote basic computer application learning in rural areas of China.

  6. An Exploratory Comparison Study of Inventor-authors with Their Non-patenting Peers in Research Productivity and Influence

    Directory of Open Access Journals (Sweden)

    Szu-chia Scarlett Lo

    2014-12-01

    Full Text Available The aim of this study is to explore the possible link between industrial technology development and scientific research, with specific focus on the development of industrial technology influences the inventor-authors’ performance on scientific research. In this study, patenting activity was seen as representation of output of industrial technology; advised theses, funded research projects and journal articles were used as indicators of scientific research outcome. The author tried to examine the patents granted to and research output generated by members affiliated with Taiwanese Universities to reveal the productivity distribution and research performances of inventor-authors and non-patenting peers by taking bibliometrics approach. Patenting Activity Index and Academic Activity Index were used for presenting research output. Results showed that Inventor-authors performed above average both in technology development and research activities. However, it is worth a closer look at the impact of collaboration and research strategies for future researches.

  7. Active microorganisms as drivers of dynamic processes in soil: integration of basic teaching into research

    Science.gov (United States)

    Blagodatskaya, Evgenia; Kuzyakov, Yakov

    2013-04-01

    Traditionally lecture courses, seminars and even practical training are disconnected from real experimental studies and from ongoing research projects. As a result students passively participate in lectures and are helpless when they come to the laboratory to prepare their BSc or MSc theses. We introduce a training course, which is developed for Bachelor students to integrate the basic knowledge on soil microbiology and modern microbiological methods in ecological studies. The training course is focused on the importance of active microbial biomass as biogeochemical driver of soil processes. According to our concept soil functioning is closely related to and depends on the microbial activities, and only active microorganisms drive all processes. Despite this importance of active microorganisms, the most of methods are focused on the estimation of the total microbial biomass and fail to evaluate its activity. Our course demonstrates how the active physiological state of soil microorganisms can be related to the activity indicators such as respiration, molecular biomarkers and viable cell compartments (ATP, PLFA, RNA) determined in situ in soil. Each lecture begins with the set of provocative questions "What is wrong?" which help students to activate their knowledge from previous lectures. Information on on-going soil incubation experiments is integrated in the lectures as a special block. The students are required not only to learn the existing methods but to compare them and to evaluate critically the applicability of these methods to explain the results of on-going experiments. The seminars foreseen within training course are focused on critical discussions of the protocols and their adaptations to current experimental tasks. During practical part of training courses the students are associated in small research groups with a certain ecological tasks. Each group uses soil sub-samples from ongoing experiments and thus, the experimental data obtaining during the

  8. Basic and Applied Materials Science Research Efforts at MSFC Germane to NASA Goals

    Science.gov (United States)

    2003-01-01

    Presently, a number of investigations are ongoing that blend basic research with engineering applications in support of NASA goals. These include (1) "Pore Formation and Mobility (PFMI) " An ISS Glovebox Investigation" NASA Selected Project - 400-34-3D; (2) "Interactions Between Rotating Bodies" Center Director's Discretionary Fund (CDDF) Project - 279-62-00-16; (3) "Molybdenum - Rhenium (Mo-Re) Alloys for Nuclear Fuel Containment" TD Collaboration - 800-11-02; (4) "Fabrication of Alumina - Metal Composites for Propulsion Components" ED Collaboration - 090-50-10; (5) "Radiation Shielding for Deep-Space Missions" SD Effort; (6) "Other Research". In brief, "Pore Formation and Mobility" is an experiment to be conducted in the ISS Microgravity Science Glovebox that will systematically investigate the development, movement, and interactions of bubbles (porosity) during the controlled directional solidification of a transparent material. In addition to promoting our general knowledge of porosity physics, this work will serve as a guide to future ISS experiments utilizing metal alloys. "Interactions Between Rotating Bodies" is a CDDF sponsored project that is critically examining, through theory and experiment, claims of "new" physics relating to gravity modification and electric field effects. "Molybdenum - Rhenium Alloys for Nuclear Fuel Containment" is a TD collaboration in support of nuclear propulsion. Mo-Re alloys are being evaluated and developed for nuclear fuel containment. "Fabrication of Alumina - Metal Composites for Propulsion Components" is an ED collaboration with the intent of increasing strength and decreasing weight of metal engine components through the incorporation of nanometer-sized alumina fibers. "Radiation Shielding for Deep-Space Missions" is an SD effort aimed at minimizing the health risk from radiation to human space voyagers; work to date has been primarily programmatic but experiments to develop hydrogen-rich materials for shielding are

  9. The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis.

    Science.gov (United States)

    Heijman, Jordi; Algalarrondo, Vincent; Voigt, Niels; Melka, Jonathan; Wehrens, Xander H T; Dobrev, Dobromir; Nattel, Stanley

    2016-04-01

    Atrial fibrillation (AF) is an extremely common clinical problem associated with increased morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation, and surgical therapies, and have significantly improved clinical outcomes. However, their efficacy remains suboptimal, and their use is limited by a variety of potentially serious adverse effects. There is a clear need for improved therapeutic options. Several decades of research have substantially expanded our understanding of the basic mechanisms of AF. Ectopic firing and re-entrant activity have been identified as the predominant mechanisms for arrhythmia initiation and maintenance. However, it has become clear that the clinical factors predisposing to AF and the cellular and molecular mechanisms involved are extremely complex. Moreover, all AF-promoting and maintaining mechanisms are dynamically regulated and subject to remodelling caused by both AF and cardiovascular disease. Accordingly, the initial presentation and clinical progression of AF patients are enormously heterogeneous. An understanding of arrhythmia mechanisms is widely assumed to be the basis of therapeutic innovation, but while this assumption seems self-evident, we are not aware of any papers that have critically examined the practical contributions of basic research into AF mechanisms to arrhythmia management. Here, we review recent insights into the basic mechanisms of AF, critically analyse the role of basic research insights in the development of presently used anti-AF therapeutic options and assess the potential value of contemporary experimental discoveries for future therapeutic innovation. Finally, we highlight some of the important challenges to the translation of basic science findings to clinical application.

  10. Research planning for new materials development based on basic · interdisciplinary science

    International Nuclear Information System (INIS)

    This work is aimed to apply the super-interface theory to the basic · interdisciplinary science to find novel material and establish the basic technology for future economy. For this purpose, definition of the super-interface theory and new material, classification of three characteristics and four application fields for the super-interface theory, and planning the technology development roadmap were conducted. Through this work, the national competitiveness in the field of the new material development can be maximized by suggesting the development direction of multi-functional material based on the basic · interdisciplinary science

  11. The 15th Meeting of China-Korea Joint Committee for Basic Scientific Research held in Busan%The 15th Meeting of China-Korea Joint Committee for Basic Scientific Research held in Busan

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The 15th Meeting of the China-Korea Joint Committee for Basic Scientific Research was successfullyheld in Busan, Korea on June 16, 2011. 33 bilateral cooperative projects were selected by the Committee forFY2011, including 21 joint research projects and 12 joint seminars. The Committee members made indepth discussions on the issues of strengthening future cooperation and topics for the Northeastern Asian Symposium.

  12. Assistance to Tourism: Exploratory Estimates

    OpenAIRE

    Productivity Commission

    2005-01-01

    In April 2005, the research paper into ‘Assistance to Tourism: Exploratory Estimates’ was released. It is the first comprehensive attempt to quantify the extent of assistance to tourism on a comparable basis to that for other industries in Australia. While care is needed in interpreting the results, the estimates suggest that tourism receives a lower rate of Australian Government assistance than the average for the manufacturing and primary sectors, but more than for other service industries....

  13. Summary Report for Personal Chemical Exposure Informatics: Visualization and Exploratory Research in Simulations and Systems (PerCEIVERS)

    Science.gov (United States)

    EPA Research Pathfinder Innovation Projects (PIPs), an internal competition for Agency scientists, was launched in 2010 to solicit innovative research proposals that would help the Agency to advance science for sustainability. In 2011, of the 117 proposals received from almost 30...

  14. Methodological Synthesis in Quantitative L2 Research: A Review of Reviews and a Case Study of Exploratory Factor Analysis

    Science.gov (United States)

    Plonsky, Luke; Gonulal, Talip

    2015-01-01

    Research synthesis and meta-analysis provide a pathway to bring together findings in a given domain with greater systematicity, objectivity, and transparency than traditional reviews. The same techniques and corresponding benefits can be and have been applied to examine methodological practices in second language (L2) research (e.g., Plonsky,…

  15. Stem Cell Basics

    Science.gov (United States)

    ... Information Stem Cell Basics Stem Cell Basics: Introduction Stem Cell Information General Information Clinical Trials Funding Information Current Research Policy Glossary Site Map Stem Cell Basics Introduction: What are stem cells, and why ...

  16. An exploratory survey of professionals on the use of stored tissue samples from minors for genetic research.

    Science.gov (United States)

    Hens, K; Snoeck, J; Nys, H; Cassiman, J-J; Dierickx, K

    2010-01-01

    he ethical aspects of the use of stored tissue samples collected from minors are of topical interest. However, the views of professionals working in the field of genetics have not been investigated in depth anywhere. We conducted a survey among 194 such professionals in Belgium. This list was composed of the members of the High Council for Anthropogenetics, supplemented with all professionals working in the field of genetics that we found on the websites of the eight Belgian centers of human genetics and of the associated university registries. We achieved a response rate of 35.5%. The vast majority (92%) think that research on stored tissue samples is useful. Most respondents stated that parental consent is valid (82.5%), and 76.5% thought that children should also be given the right to assent when they are able to comprehend the implications of the storage of biological samples and of genetic research. Slightly more than half put the age at which young people can understand storage or research rather high: 16-18 years (51 and 53.1%, respectively). Although there is some consensus in the literature that donors should be allowed to give broad consent for future research on their biological samples, only 47.6% in our survey thought that parents should be allowed to consent to any future research on their children's samples. The aim of our study was to give some basis for future ethical reflections and policies on the subject of stored tissue samples from minors for genetic research. We concluded that a large majority of Belgian researchers and clinicians in the field of genetic research think research on stored tissue samples from minors is useful. They also think that parental consent for such research is valid, but that children should be allowed to assent as they grow older.

  17. Is basic science disappearing from medicine? The decline of biomedical research in the medical literature.

    Science.gov (United States)

    Steinberg, Benjamin E; Goldenberg, Neil M; Fairn, Gregory D; Kuebler, Wolfgang M; Slutsky, Arthur S; Lee, Warren L

    2016-02-01

    Explosive growth in our understanding of genomics and molecular biology have fueled calls for the pursuit of personalized medicine, the notion of harnessing biologic variability to provide patient-specific care. This vision will necessitate a deep understanding of the underlying pathophysiology in each patient. Medical journals play a pivotal role in the education of trainees and clinicians, yet we suspected that the amount of basic science in the top medical journals has been in decline. We conducted an automated search strategy in PubMed to identify basic science articles and calculated the proportion of articles dealing with basic science in the highest impact journals for 8 different medical specialties from 1994 to 2013. We observed a steep decline (40-60%) in such articles over time in almost all of the journals examined. This rapid decline in basic science from medical journals is likely to affect practitioners' understanding of and interest in the basic mechanisms of disease and therapy. In this Life Sciences Forum, we discuss why this decline may be occurring and what it means for the future of science and medicine.

  18. Basic research in support of innovative fuels design for the Generation IV systems (F-BRIDGE project)

    International Nuclear Information System (INIS)

    F-BRIDGE (Basic Research in support of Innovative Fuels Design for the GEN IV systems) is a 4-year project which started in 2008. It seeks to bridge the gap between basic research and technological applications for generation IV nuclear reactor systems. One of the challenges for the next generation of reactors is to significantly increase the efficiency in designing innovative fuels. The object of the F-BRIDGE project is to complement the empirical approach by a physically-based description of fuel and cladding materials to enable a rationalization of the design process and a better selection of promising fuel systems. Advanced modelling and separate effects experiments are carried out in order to obtain more exact physical descriptions of ceramic fuels and cladding, at relevant scales from the atomic to the macroscopic scale. Research is also focused on assessing and improving 'sphere-pac' fuel, a composite-ceramics concept which has shown promise. The project activities can be broken down into four main areas: (i) Basic research investigations using a multi-scale approach in both experimentation and modelling to enable the generation of missing basic data, the identification of relevant mechanisms and the development of appropriate models; (ii) Transfer between technological issues and basic research by bringing together within the same project materials scientists, engineers and end-users; (iii) Assessment of the drawbacks and benefits of the sphere-pac fuel application to various Generation IV systems; (iv) Education and training to promote research in the field of fuel materials, to ensure the exchange of results and ideas among the participants and to link the project with other related European or international initiatives. The project relies on the complementary expertise of 19 partners: nuclear and non nuclear research organisations, universities, a nuclear engineering company, as well as technology and project management consultancy small and medium

  19. Basic Research Needs for Solar Energy Utilization. Report of the Basic Energy Sciences Workshop on Solar Energy Utilization, April 18-21, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, N. S.; Crabtree, G.; Nozik, A. J.; Wasielewski, M. R.; Alivisatos, P.; Kung, H.; Tsao, J.; Chandler, E.; Walukiewicz, W.; Spitler, M.; Ellingson, R.; Overend, R.; Mazer, J.; Gress, M.; Horwitz, J.; Ashton, C.; Herndon, B.; Shapard, L.; Nault, R. M.

    2005-04-21

    World demand for energy is projected to more than double by 2050 and to more than triple by the end of the century. Incremental improvements in existing energy networks will not be adequate to supply this demand in a sustainable way. Finding sufficient supplies of clean energy for the future is one of society?s most daunting challenges. Sunlight provides by far the largest of all carbon-neutral energy sources. More energy from sunlight strikes the Earth in one hour (4.3 ? 1020 J) than all the energy consumed on the planet in a year (4.1 ? 1020 J). We currently exploit this solar resource through solar electricity ? a $7.5 billion industry growing at a rate of 35?40% per annum ? and solar-derived fuel from biomass, which provides the primary energy source for over a billion people. Yet, in 2001, solar electricity provided less than 0.1% of the world's electricity, and solar fuel from modern (sustainable) biomass provided less than 1.5% of the world's energy. The huge gap between our present use of solar energy and its enormous undeveloped potential defines a grand challenge in energy research. Sunlight is a compelling solution to our need for clean, abundant sources of energy in the future. It is readily available, secure from geopolitical tension, and poses no threat to our environment through pollution or to our climate through greenhouse gases. This report of the Basic Energy Sciences Workshop on Solar Energy Utilization identifies the key scientific challenges and research directions that will enable efficient and economic use of the solar resource to provide a significant fraction of global primary energy by the mid 21st century. The report reflects the collective output of the workshop attendees, which included 200 scientists representing academia, national laboratories, and industry in the United States and abroad, and the U.S. Department of Energy?s Office of Basic Energy Sciences and Office of Energy Efficiency and Renewable Energy.

  20. The theoretical research of basic function method in incompressible viscous flow and its simulations in three-dimensional aneurysms

    Institute of Scientific and Technical Information of China (English)

    SHEN Fang; WU WangYi

    2009-01-01

    Basic function method is developed to treat the incompressible viscous flow. Artificial compressibility coefficient, the technique of flux splitting method and the combination of central and upwind schemes are applied to construct the basic function scheme of trigonometric function type for solving three-dimensional incompressible Navier-Stokes equations numerically. To prove the method, flows in finite-length-pipe are calculated, the velocity and pressure distribution of which solved by our method quite coincide with the exact solutions of Poiseuille flow except in the areas of entrance and exit. After the method is proved elementary, the hemodynamics in two- and three-dimensional aneurysms is researched numerically by using the basic function method of trigonometric function type and unstructured grids generation technique. The distributions of velocity, pressure and shear force in steady flow of aneurysms are calculated, and the influence of the shape of the aneurysms on the hemodynamics is studied.

  1. The theoretical research of basic function method in incompressible viscous flow and its simulations in three-dimensional aneurysms

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Basic function method is developed to treat the incompressible viscous flow. Artificial compressibility coefficient, the technique of flux splitting method and the combination of central and upwind schemes are applied to construct the basic function scheme of trigonometric function type for solving three-dimensional incompressible Navier-Stokes equations numerically. To prove the method, flows in finite-length-pipe are calculated, the velocity and pressure distribution of which solved by our method quite coincide with the exact solutions of Poiseuille flow except in the areas of entrance and exit. After the method is proved elementary, the hemodynamics in two-and three-dimensional aneurysms is researched numerically by using the basic function method of trigonometric function type and unstructured grids generation technique. The distributions of velocity, pressure and shear force in steady flow of aneurysms are calculated, and the influence of the shape of the aneurysms on the hemodynamics is studied.

  2. Faculty Motivations: An Exploratory Study of Motivational Factors of Faculty to Assist with Students’ Research Skills Development

    Directory of Open Access Journals (Sweden)

    Laurie Morrison

    2007-12-01

    Full Text Available Based on the premise that collaboration with faculty is a core element for the success of an IL program, this study sought to investigate the intrinsic motivations of faculty to assist their students’ development of information literacy skills. Research into the relationship between faculty and the library and librarians has left many unanswered questions about why faculty value research skills yet appear to be resistant to opportunities to collaborate with a librarian. The question arises: does attitude sufficiently predict the behaviour of faculty? Motivation (the underlying energy and direction of behaviour may be a more likely predictor of behaviour. This article reports findings from qualitative study which sought to uncover the motivational factors of faculty to address the library research skills of students. In-depth, semi-structured interviews were conducted in the fall semester 2004 with teaching faculty at the University of Guelph. Participants were asked to discuss their use of course-integrated library/research instruction. In its absence, faculty were asked how (if at all did they assist students to learn to do research. Transcripts were analyzed using grounded theory methodology. Findings suggest that faculty are motivated by their desire to produce independent learners with transferable skills. Scholars look for potential students for the next generation of scholars – graduate students. They see a link between the development of research skills and readers –an audience for their work. Some participants who had not previously collaborated with a librarian described their own methods of integrating research skills development in the curriculum. Findings are encouraging and support librarians in their efforts to promote information literacy instruction as a critical skill in undergraduate education.

  3. Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease.

    Science.gov (United States)

    Avila, Jesus; Hernandez, Felix; Wandosell, Francisco; Lucas, Jose J; Esteban, Jose A; Ledesma, M Dolores; Bullido, Maria J

    2010-01-01

    One important aspect of studies carried out at the Center for Molecular Biology "Severo Ochoa" is focused on basic aspects of Alzheimer's disease, mainly the search for suitable therapeutic targets for this disorder. Several groups at the Center are involved in these studies, and, in this spotlight, the work they are carrying out will be described.

  4. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. (research article)

    NARCIS (Netherlands)

    L. Schaeffer; R. Roy (Richard); S. Humbert; V. Moncollin; W. Vermeulen (Wim); J.H.J. Hoeijmakers (Jan); P. Chambon; J-M. Egly (Jean-Marc)

    1993-01-01

    textabstractThe human BTF2 basic transcription factor (also called TFIIH), which is similar to the delta factor in rat and factor b in yeast, is required for class II gene transcription. A strand displacement assay was used to show that highly purified preparation of BTF2 had an adenosine triphospha

  5. Personality Characteristics and Learning Style Preferences of Adult Basic Education Students. Research Monograph.

    Science.gov (United States)

    Manzo, Anthony V.; And Others

    The study described in the report identifies personality characteristics and learning styles of adult basic education (ABE) students on the basis of three instruments: the Luscher Color Test, the Manzo Bestiary Inventory, and the Learning Preference Inventory. The volunteer sample consisted of 83 ABE students. Subsample comparison groups consisted…

  6. Without continuous basic research technology will stagnate and economy will be in no growth. Why?

    DEFF Research Database (Denmark)

    Pedersen, Jørgen Lindgaard

    2008-01-01

    The paper presents some ideas about new knowledge and the effects from knowledge on development of new technology. Paul M. Romer established in the 1980s the so-called New Growth Economy. The basic idea is here that knowledge is included explicitly in the production function. With knowledge...

  7. Financing Basic Education in Bangladesh. CREATE Pathways to Access. Research Monograph No. 12

    Science.gov (United States)

    Al-Samarrai, Samer

    2007-01-01

    This paper presents education finance trends for Bangladesh since 2000. It shows that while government spending on education as a proportion of national income has stagnated, it has increased in real terms. Real increases in education spending have resulted in substantial increases in per student spending in basic education. At primary, enrolment…

  8. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    Science.gov (United States)

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2013-01-01

    Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…

  9. Faculty Motivations: An Exploratory Study of Motivational Factors of Faculty to Assist with Students’ Research Skills Development

    Directory of Open Access Journals (Sweden)

    Laurie Morrison

    2007-09-01

    Full Text Available This article reports the findings of a qualitative study which sought to uncover the motivational factors of faculty to address the library research skills of students. In-depth, semi-structured interviews were conducted in the fall semester of 2004 with teaching faculty, users and non-users of library instruction, at the University of Guelph. Participants were asked to discuss their use of course-integrated library/research instruction. In its absence, faculty were asked how (if at all did they assist students to learn to do research. Transcripts were analyzed using grounded theory methodology. Findings may be useful to instructional librarians seeking to enhance collaboration with faculty. One finding is a suggestion that faculty are motivated by their desire to produce independent learners with transferable skills. Scholars look to potential students for the next generation of scholars – graduate students. They see a link between the development of research skills and readers – scholarly community, an audience for their work. Some participants who had not previously collaborated with a librarian described their own methods of integrating research skills development into the curriculum.

  10. An Exploratory Study of Factors That Affect the Research Progress of International PhD Students from the Middle East

    Science.gov (United States)

    Khozaei, Fatemeh; Naidu, Sivabala; Khozaei, Zahra; Salleh, Nor Aini

    2015-01-01

    Purpose: Despite the critical issues involving Middle East countries such as war and a drop in currency exchange rates, a large number of students leave their country to pursue a higher education abroad, every year. The purpose of this paper is to understand the difficulties that these students face while conducting their research in a foreign…

  11. An Exploratory Investigation on Modularity Adoption in Design and Production Through a Case-Based Research in a Brazilian Automaker

    DEFF Research Database (Denmark)

    Cauchick Miguel, Paulo Augusto; Hsuan, Juliana

    2010-01-01

    to what extent the adoption of modularity varies according to such tradeoffs. Case-based research is employed as the methodological approach. The unit of analysis is a business unit of an international leading manufacturer of trucks and buses, being the latter within the scope of the present investigation...

  12. Exploratory research for the development of a computer aided software design environment with the software technology program

    Science.gov (United States)

    Hardwick, Charles

    1991-01-01

    Field studies were conducted by MCC to determine areas of research of mutual interest to MCC and JSC. NASA personnel from the Information Systems Directorate and research faculty from UHCL/RICIS visited MCC in Austin, Texas to examine tools and applications under development in the MCC Software Technology Program. MCC personnel presented workshops in hypermedia, design knowledge capture, and design recovery on site at JSC for ISD personnel. The following programs were installed on workstations in the Software Technology Lab, NASA/JSC: (1) GERM (Graphic Entity Relations Modeler); (2) gIBIS (Graphic Issues Based Information System); and (3) DESIRE (Design Recovery tool). These applications were made available to NASA for inspection and evaluation. Programs developed in the MCC Software Technology Program run on the SUN workstation. The programs do not require special configuration, but they will require larger than usual amounts of disk space and RAM to operate properly.

  13. Student science publishing: an exploratory study of undergraduate science research journals and popular science magazines in the US and Europe

    OpenAIRE

    Mico Tatalovic

    2008-01-01

    Science magazines have an important role in disseminating scientific knowledge into the public sphere and in discussing the broader scope affected by scientific research such as technology, ethics and politics. Student-run science magazines afford opportunities for future scientists, communicators, politicians and others to practice communicating science. The ability to translate ‘scientese’ into a jargon-free discussion is rarely easy: it requires practice, and student magazines may provide ...

  14. Inhibitions and implications associated with celebrity participation in social marketing programs focusing on HIV prevention: an exploratory research

    OpenAIRE

    Beatriz Casais; Proença, João F.

    2010-01-01

    This paper discusses celebrity participation in social marketing programs focusing on public health, especially on HIV programs. The research identifies the inhibitions of celebrity people and implications that this involvement may have upon their lives. The paper analysis data from in-depth interviews made to twenty-seven Portuguese celebrities from arts, show business and sports. The results show absence of prejudice against HIV. Famous people feel motivated to join public health and HIV ca...

  15. INTERNATIONAL MARKETING RESEARCH: BASIC CHARACTERISTICS AND THEIR IMPORTANCE FOR ECONOMY IN TRANSITION

    OpenAIRE

    Vedran Stanetić

    2012-01-01

    This paper aims to highlight thebasic characteristics of international marketingresearches and their importance to the economiesin transition. The idea, which the author has alwayshad in mind when he wrote the following lines, ishow to describe and explain in concise andaffordable way the basic principles governingresearch in an international environment, as wellas the possibility of their fastest and easiestimplementation, always emphasizing the differencesbetween international and national,...

  16. Basic versus applied research: Julius Sachs (1832–1897) and the experimental physiology of plants

    OpenAIRE

    Kutschera, Ulrich

    2015-01-01

    The German biologist Julius Sachs was the first to introduce controlled, accurate, quantitative experimentation into the botanical sciences, and is regarded as the founder of modern plant physiology. His seminal monograph Experimental-Physiologie der Pflanzen (Experimental Physiology of Plants) was published 150 y ago (1865), when Sachs was employed as a lecturer at the Agricultural Academy in Poppelsdorf/Bonn (now part of the University). This book marks the beginning of a new era of basic a...

  17. Prizes for Basic Research – Human Capital, Economic Might and the Shadow of History*

    OpenAIRE

    Aizenman, Joshua; Noy, Ilan

    2006-01-01

    This paper studies the impact of global factors on patterns of basic research across countries and time. We rely on the records of major scientific awards, and on data dealing with global economic and historical trends. Specifically, we investigate the degree to which scale or threshold effects account for countries share of major prizes [Nobel, Fields, Kyoto and Wolf]. We construct a stylized model, predicting that lagged relative GDP of a country relative to the GDP of all countries engagin...

  18. Student science publishing: an exploratory study of undergraduate science research journals and popular science magazines in the US and Europe

    Directory of Open Access Journals (Sweden)

    Mico Tatalovic

    2008-09-01

    Full Text Available Science magazines have an important role in disseminating scientific knowledge into the public sphere and in discussing the broader scope affected by scientific research such as technology, ethics and politics. Student-run science magazines afford opportunities for future scientists, communicators, politicians and others to practice communicating science. The ability to translate ‘scientese’ into a jargon-free discussion is rarely easy: it requires practice, and student magazines may provide good practice ground for undergraduate and graduate science students wishing to improve their communication skills.

  19. Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research.

    Science.gov (United States)

    Stover, Alexander E; Herculian, Siranush; Banuelos, Maria G; Navarro, Samantha L; Jenkins, Michael P; Schwartz, Philip H

    2016-01-01

    This paper describes how to use a custom manufactured, commercially available enclosed cell culture system for basic and preclinical research. Biosafety cabinets (BSCs) and incubators have long been the standard for culturing and expanding cell lines for basic and preclinical research. However, as the focus of many stem cell laboratories shifts from basic research to clinical translation, additional requirements are needed of the cell culturing system. All processes must be well documented and have exceptional requirements for sterility and reproducibility. In traditional incubators, gas concentrations and temperatures widely fluctuate anytime the cells are removed for feeding, passaging, or other manipulations. Such interruptions contribute to an environment that is not the standard for cGMP and GLP guidelines. These interruptions must be minimized especially when cells are utilized for therapeutic purposes. The motivation to move from the standard BSC and incubator system to a closed system is that such interruptions can be made negligible. Closed systems provide a work space to feed and manipulate cell cultures and maintain them in a controlled environment where temperature and gas concentrations are consistent. This way, pluripotent and multipotent stem cells can be maintained at optimum health from the moment of their derivation all the way to their eventual use in therapy. PMID:27341536

  20. Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research

    Science.gov (United States)

    Stover, Alexander E.; Herculian, Siranush; Banuelos, Maria G.; Navarro, Samantha L.; Jenkins, Michael P.; Schwartz, Philip H.

    2016-01-01

    This paper describes how to use a custom manufactured, commercially available enclosed cell culture system for basic and preclinical research. Biosafety cabinets (BSCs) and incubators have long been the standard for culturing and expanding cell lines for basic and preclinical research. However, as the focus of many stem cell laboratories shifts from basic research to clinical translation, additional requirements are needed of the cell culturing system. All processes must be well documented and have exceptional requirements for sterility and reproducibility. In traditional incubators, gas concentrations and temperatures widely fluctuate anytime the cells are removed for feeding, passaging, or other manipulations. Such interruptions contribute to an environment that is not the standard for cGMP and GLP guidelines. These interruptions must be minimized especially when cells are utilized for therapeutic purposes. The motivation to move from the standard BSC and incubator system to a closed system is that such interruptions can be made negligible. Closed systems provide a work space to feed and manipulate cell cultures and maintain them in a controlled environment where temperature and gas concentrations are consistent. This way, pluripotent and multipotent stem cells can be maintained at optimum health from the moment of their derivation all the way to their eventual use in therapy. PMID:27341536

  1. Determinants of personal protective equipment (PPE) use in UK motorcyclists: exploratory research applying an extended theory of planned behaviour.

    Science.gov (United States)

    Norris, Emma; Myers, Lynn

    2013-11-01

    Despite evident protective value of motorcycle personal protective equipment (PPE), no research has assessed considerations behind its uptake in UK riders. A cross-sectional online questionnaire design was employed, with riders (n=268) recruited from online motorcycle forums. Principal component analysis found four PPE behavioural outcomes. Theoretical factors of intentions, attitudes, injunctive and descriptive subjective norms, risk perceptions, anticipated regret, benefits and habit were also identified for further analysis. High motorcycle jacket, trousers and boots wear, middling high-visibility wear and low non-Personal Protective Equipment wear were found. Greater intentions, anticipated regret and perceived benefits were significantly associated with increased motorcycle jacket, trousers and boots wear, with habit presence and scooter use significantly associated with increased high-visibility wear. Lower intentions, anticipated regret and risk perceptions, being female, not holding a car licence and urban riding were significantly associated with increased non-PPE wear. A need for freedom of choice and mixed attitudes towards PPE use were evident in additional comments. PPE determinants in this sample provide a preliminary basis for future uptake interventions. Larger scale and qualitative research is needed to further investigate relevant constructs. PMID:24076303

  2. Structure, function and five basic needs of the global health research system

    OpenAIRE

    Rudan, Igor; Sridhar, Devi

    2016-01-01

    BACKGROUND: Two major initiatives that were set up to support and co-ordinate global health research efforts have been largely discontinued in recent years: the Global Forum for Health Research and World Health Organization's Department for Research Policy and Cooperation. These developments provide an interesting case study into the factors that contribute to the sustainability of initiatives to support and co-ordinate global health research in the 21st century.METHODS: We reviewed the histo...

  3. Initial phase of the Hans-Ertel Centre for Weather Research – A virtual centre at the interface of basic and applied weather and climate research

    Directory of Open Access Journals (Sweden)

    Martin Weissmann

    2014-09-01

    Full Text Available The Hans-Ertel Centre for Weather Research is a network of German universities, research institutes and the German Weather Service (Deutscher Wetterdienst, DWD. It has been established to trigger and intensify basic research and education on weather forecasting and climate monitoring. The performed research ranges from nowcasting and short-term weather forecasting to convective-scale data assimilation, the development of parameterizations for numerical weather prediction models, climate monitoring and the communication and use of forecast information. Scientific findings from the network contribute to better understanding of the life-cycle of shallow and deep convection, representation of uncertainty in ensemble systems, effects of unresolved variability, regional climate variability, perception of forecasts and vulnerability of society. Concrete developments within the research network include dual observation-microphysics composites, satellite forward operators, tools to estimate observation impact, cloud and precipitation system tracking algorithms, large-eddy-simulations, a regional reanalysis and a probabilistic forecast test product. Within three years, the network has triggered a number of activities that include the training and education of young scientists besides the centre's core objective of complementing DWD's internal research with relevant basic research at universities and research institutes. The long term goal is to develop a self-sustaining research network that continues the close collaboration with DWD and the national and international research community.

  4. Team Exploratory Testing Sessions

    OpenAIRE

    Soili Saukkoriipi; Ilkka Tervonen

    2012-01-01

    Exploratory testing (ET) is popular, especially among agile development teams. In this paper, we study the team aspect in the ET context and explore how to use ET in team sessions to complement other testing activities. The goal was to define a team exploratory testing (TET) session approach and to provide evidence that the approach is worth using. A TET session approach is defined by means of parameters, roles, and process. Also, instructions for using the approach are given. The team is the...

  5. Optimising Translational Research Opportunities: A Systematic Review and Narrative Synthesis of Basic and Clinician Scientists' Perspectives of Factors Which Enable or Hinder Translational Research

    Science.gov (United States)

    Sadler, Euan; Fisher, Helen R.; Maher, John; Wolfe, Charles D. A.; McKevitt, Christopher

    2016-01-01

    Introduction Translational research is central to international health policy, research and funding initiatives. Despite increasing use of the term, the translation of basic science discoveries into clinical practice is not straightforward. This systematic search and narrative synthesis aimed to examine factors enabling or hindering translational research from the perspective of basic and clinician scientists, a key stakeholder group in translational research, and to draw policy-relevant implications for organisations seeking to optimise translational research opportunities. Methods and Results We searched SCOPUS and Web of Science from inception until April 2015 for papers reporting scientists’ views of the factors they perceive as enabling or hindering the conduct of translational research. We screened 8,295 papers from electronic database searches and 20 papers from hand searches and citation tracking, identifying 26 studies of qualitative, quantitative or mixed method designs. We used a narrative synthesis approach and identified the following themes: 1) differing concepts of translational research 2) research processes as a barrier to translational research; 3) perceived cultural divide between research and clinical care; 4) interdisciplinary collaboration as enabling translation research, but dependent on the quality of prior and current social relationships; 5) translational research as entrepreneurial science. Across all five themes, factors enabling or hindering translational research were largely shaped by wider social, organisational, and structural factors. Conclusion To optimise translational research, policy could consider refining translational research models to better reflect scientists’ experiences, fostering greater collaboration and buy in from all types of scientists. Organisations could foster cultural change, ensuring that organisational practices and systems keep pace with the change in knowledge production brought about by the

  6. An economic and financial exploratory

    Science.gov (United States)

    Cincotti, S.; Sornette, D.; Treleaven, P.; Battiston, S.; Caldarelli, G.; Hommes, C.; Kirman, A.

    2012-11-01

    This paper describes the vision of a European Exploratory for economics and finance using an interdisciplinary consortium of economists, natural scientists, computer scientists and engineers, who will combine their expertise to address the enormous challenges of the 21st century. This Academic Public facility is intended for economic modelling, investigating all aspects of risk and stability, improving financial technology, and evaluating proposed regulatory and taxation changes. The European Exploratory for economics and finance will be constituted as a network of infrastructure, observatories, data repositories, services and facilities and will foster the creation of a new cross-disciplinary research community of social scientists, complexity scientists and computing (ICT) scientists to collaborate in investigating major issues in economics and finance. It is also considered a cradle for training and collaboration with the private sector to spur spin-offs and job creations in Europe in the finance and economic sectors. The Exploratory will allow Social Scientists and Regulators as well as Policy Makers and the private sector to conduct realistic investigations with real economic, financial and social data. The Exploratory will (i) continuously monitor and evaluate the status of the economies of countries in their various components, (ii) use, extend and develop a large variety of methods including data mining, process mining, computational and artificial intelligence and every other computer and complex science techniques coupled with economic theory and econometric, and (iii) provide the framework and infrastructure to perform what-if analysis, scenario evaluations and computational, laboratory, field and web experiments to inform decision makers and help develop innovative policy, market and regulation designs.

  7. How Asking a Very Basic Research Question Led Us to a Model for at Least Three Diseases | Poster

    Science.gov (United States)

    By Howard Young Editor’s note: This article is adapted from Dr. Young’s January 12, 2015, post to the I am Intramural Blog of the Intramural Research Program. When I started this project, it was not my objective to develop a model for any specific disease, nor did I even suspect that the ultimate result would be some insight into autoimmune disease. The basic research question I was asking was why there are sequences in the 3′ untranslated region (3′UTR) of the interferon-gamma (IFN-gamma) mRNA that are more highly conserved than in the coding region of the gene.

  8. Basic research for nuclear energy. y Study on the nuclear materials technology

    Energy Technology Data Exchange (ETDEWEB)

    Kuk, I. H.; Lee, H. S.; Jeong, Y. H.; Sung, K. W.; Han, J. H.; Lee, J. T.; Lee, H. K.; Kim, S. J.; Kang, H. S.; An, D. H.; Kim, K. R.; Park, S. D.; Han, C. H.; Jung, M. K.; Oh, Y. J.; Kim, K. H.; Kim, S. H.; Back, J. H.; Kim, C. H.; Lim, K. S.; Kim, Y. Y.; Na, J. W.; Ku, J. H.; Lee, D. H.

    1996-12-01

    A study on the nuclear materials technologies which are necessary to establish the base for alloy development was performed. - The feasibility study on the application of Zircaloy scrap waste for hydrogen storage - The development of metal hydride battery for energy storage system - The establishment of transmission electron microscopy database for nuclear materials - The basic technology for the development of cladding materials for high burnup - The water chemistry technology for secondary system pH control and the photocatalysis technology for decomposition and removal of organics. - Improvement of primary component integrity of PWR by Zinc injection. (author). 175 refs., 58 tabs., 262 figs.

  9. Basic research for nuclear energy. y Study on the nuclear materials technology

    International Nuclear Information System (INIS)

    A study on the nuclear materials technologies which are necessary to establish the base for alloy development was performed. - The feasibility study on the application of Zircaloy scrap waste for hydrogen storage - The development of metal hydride battery for energy storage system - The establishment of transmission electron microscopy database for nuclear materials - The basic technology for the development of cladding materials for high burnup - The water chemistry technology for secondary system pH control and the photocatalysis technology for decomposition and removal of organics. - Improvement of primary component integrity of PWR by Zinc injection. (author). 175 refs., 58 tabs., 262 figs

  10. Without continuous basic research technology will stagnate and economy will be in no growth. Why?

    OpenAIRE

    Pedersen, Jørgen Lindgaard

    2008-01-01

    The paper presents some ideas about new knowledge and the effects from knowledge on development of new technology. Paul M. Romer established in the 1980s the so-called New Growth Economy. The basic idea is here that knowledge is included explicitly in the production function. With knowledge as a public good its unit costs will be declining and it can substitute other inputs with not-declining unit costs. A problem with that idea is the neglect of the cost connected with production of a new id...

  11. Research on the Architecture of a Basic Reconfigurable Information Communication Network

    Directory of Open Access Journals (Sweden)

    Ruimin Wang

    2013-01-01

    Full Text Available The current information network cannot fundamentally meet some urgent requirements, such as providing ubiquitous information services and various types of heterogeneous network, supporting diverse and comprehensive network services, possessing high quality communication effects, ensuring the security and credibility of information interaction, and implementing effective supervisory control. This paper provides the theory system for the basic reconfigurable information communication network based on the analysis of present problems on the Internet and summarizes the root of these problems. It also provides an in-depth discussion about the related technologies and the prime components of the architecture.

  12. Industry's demand for the BESSY synchrotron radiation (SR): approaches towards interlinking basic scientific research activities and industry

    International Nuclear Information System (INIS)

    In Germany, industry's demand for synchrotron radiation (SR) is very limited, due to the current macroeconomic situation and the corporate strategy of potential SR users in industry. This is in contrast to the conditions in the USA (and Japan), where industrial enterprises more readily invest in and run their own long-term basic research projects for exploration of potential commercial applications according to their demands, with research goals pursued there and in Germany overlapping to a large extent. It cannot be expected that demand for SR from industry in Germany will ever come up to the level seen in the USA. In Germany, non-university research institutes are most likely to become an important group of potential users of SR. Substantially boosting the demand for SR from industry will need a change of macroeconomic framework conditions affecting the corporate strategy to the effect that industry will more strongly commit itself to and take up responsibility for application-oriented fundamental research and the corresponding technology transfer. This can be achieved by a policy providing both for institutional means and financial incentives. As to near-market, strategic technological developments, establishment of structures allowing direct cooperation of science and technology, for instance in the form of joint ventures, or underwriting agreements and corresponding supervisory boards, seem to be promising. As to basic-research-oriented promotion of research, a technology screening might lead to the selection of technology-relevant research goals, and corresponding financial support from a special fund. Such incentives for cooperative action by technology, science and the government will create novel types of research-industry interfaces in Germany between ''historical'' spheres of autonomy of research of industry and the scientific community. (orig.)

  13. Mentoring Field Directors: A National Exploratory Study

    Science.gov (United States)

    Ellison, Martha L.; Raskin, Miriam S.

    2014-01-01

    In social work field education, mentoring is underused and lacks research data. There is a paucity of research that examines the effect mentoring has on social work field directors who administer field programs at the undergraduate and/or graduate level. This exploratory study fills this void by examining the mentoring opportunities and…

  14. New Progress Achieved by NSFC Project in Basic Research of Black Hole Physics

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Supported by NSFC,Prof.Wu Shuangqing from Huazhong Normal University conducted independent research on gravitation theory,discovered the exact solutions for the five-dimensional G(o)del charged rota-ting black hole in the universe,and made important headway in the characteristic research of black hole so-lutions.Part of the research results has been published in international top journal Physical Review Letters 100,121301 (2008).

  15. Research Workshop 1: Basics of Medical Journalism and How to Write a Paper

    Directory of Open Access Journals (Sweden)

    Mohammad Hadi Bagheri

    2009-01-01

    Full Text Available Objectives: The purpose of this workshop is to present an introduction to medical journalism and to describe current aspects of research writing and publication, examine the features that make research articles in English, communicate scientific findings effectively and efficiently, and help participants learn to identify and implement these features themselves. Topics to be covered are international scientific, technical and medical research publishing, writing to make the results easy to understand, good scientific English style, and responding to peer review.

  16. Basic education and research in the classroom - doi: 10.4025/actascieduc.v35i2.20649

    Directory of Open Access Journals (Sweden)

    Nilda Stecanela

    2013-05-01

    Full Text Available Relationships between the challenges of Basic Education, especially those related to contemporary school, and the research-linked educational challenges are investigated, based on theoretical reflections on the employment of research in the classroom as an educational principle. The arguments are foregrounded on the analysis of aspects associated to the genesis of education and school crises. Current paper focuses on the importance of the teachers’ reflective practice and on their constitution as researchers-teachers for the implementation of the language game provided by classroom research, taking into consideration Freire’s dialogue. It underlines the active teaching methodologies that try to bridge the communication gap between school cultures and children’s and young people’s cultures, linked to everyday life dilemmas and with experience-built knowledge.

  17. Basic Behavioral Science Research for Mental Health. Social Influence and Social Cognition.

    Science.gov (United States)

    American Psychologist, 1996

    1996-01-01

    Discusses social influence and social cognition's effect on health and social well-being, and examines the efficacy of public health campaigns, the effects of negative stereotyping, and why some teenagers resist drug use and others do not as part of the social problems addressed by behavioral science research. Future directions for research on…

  18. An International Basic Science and Clinical Research Summer Program for Medical Students

    Science.gov (United States)

    Ramjiawan, Bram; Pierce, Grant N.; Anindo, Mohammad Iffat Kabir; AlKukhun, Abedalrazaq; Alshammari, Abdullah; Chamsi, Ahmad Talal; Abousaleh, Mohannad; Alkhani, Anas; Ganguly, Pallab K.

    2012-01-01

    An important part of training the next generation of physicians is ensuring that they are exposed to the integral role that research plays in improving medical treatment. However, medical students often do not have sufficient time to be trained to carry out any projects in biomedical and clinical research. Many medical students also fail to…

  19. Seventh BES [Basic Energy Sciences] catalysis and surface chemistry research conference

    International Nuclear Information System (INIS)

    Research programs on catalysis and surface chemistry are presented. A total of fifty-seven topics are included. Areas of research include heterogeneous catalysis; catalysis in hydrogenation, desulfurization, gasification, and redox reactions; studies of surface properties and surface active sites; catalyst supports; chemical activation, deactivation; selectivity, chemical preparation; molecular structure studies; sorption and dissociation. Individual projects are processed separately for the data bases

  20. Seventh BES (Basic Energy Sciences) catalysis and surface chemistry research conference

    Energy Technology Data Exchange (ETDEWEB)

    1990-03-01

    Research programs on catalysis and surface chemistry are presented. A total of fifty-seven topics are included. Areas of research include heterogeneous catalysis; catalysis in hydrogenation, desulfurization, gasification, and redox reactions; studies of surface properties and surface active sites; catalyst supports; chemical activation, deactivation; selectivity, chemical preparation; molecular structure studies; sorption and dissociation. Individual projects are processed separately for the data bases. (CBS)

  1. Basics, common errors and essentials of statistical tools and techniques in anesthesiology research

    Science.gov (United States)

    Bajwa, Sukhminder Jit Singh

    2015-01-01

    The statistical portion is a vital component of any research study. The research methodology and the application of statistical tools and techniques have evolved over the years and have significantly helped the research activities throughout the globe. The results and inferences are not accurately possible without proper validation with various statistical tools and tests. The evidencebased anesthesia research and practice has to incorporate statistical tools in the methodology right from the planning stage of the study itself. Though the medical fraternity is well acquainted with the significance of statistics in research, there is a lack of in-depth knowledge about the various statistical concepts and principles among majority of the researchers. The clinical impact and consequences can be serious as the incorrect analysis, conclusions, and false results may construct an artificial platform on which future research activities are replicated. The present tutorial is an attempt to make anesthesiologists aware of the various aspects of statistical methods used in evidence-based research and also to highlight the common areas where maximum number of statistical errors are committed so as to adopt better statistical practices. PMID:26702217

  2. [Lay emphasis on the basic research in the field of burn surgery in China].

    Science.gov (United States)

    Hu, D H; Tao, K

    2016-07-20

    The therapeutic methods and effects have been improved greatly in burn care and management with several important advancements in the past few decades, resulting in more effective patient stabilization and significantly decreased mortality in China. However, the challenging clinical problems still exist, such as a lack of ideally efficient scheme and drugs to protect damaged tissue and internal organs after severe burn, the limited functional cosmetic outcomes of current treatment techniques and synthetic skin substitutes for deep burn wound repair and reconstruction, the high mortality of severe sepsis accompanying with burn injury patients, and the uncontrolled scar formation and modification or potential regeneration in burn wound healing, a further exploration into both underling mechanisms and curable therapies. This article emphasizes the important roles of the basic study in exploration of above clinical issues in the viewpoint of the advanced development of modern life sciences and relevant techniques. PMID:27464627

  3. The value of public health research and the division between basic vs. applied science

    Directory of Open Access Journals (Sweden)

    Almeida-Filho Naomar

    2003-01-01

    Full Text Available We question the movement towards exclusion of population and social health research from the field of science. The background under analysis is contemporary Brazil, where the scientific field that hosts this kind of research is known as Collective Health. First, the problem is formalized on logical grounds, evaluating the pertinence of considering unscientific the many objects and methods of public health research. Secondly, the cases of pulmonary tuberculosis and external causes are brought in as illustrations of the kind of scientific problem faced in health research today. The logical and epistemological basis of different forms of "scientific segregation" based on biomedical reductionism is analyzed, departing from three theses: (i the ethics of the general application of science; (ii the inappropriateness of monopolies for objectivity in the sciences; (iii the specificity of scientific fields. In the current panorama of health research in Brazil, a residual hegemonic position that defends a narrow and specific definition of the object of knowledge was found. The denial of validity and specificity to objects, methods and research techniques that constitute social and population research in health is linked to elements of irrationality in reductionism approaches. Nevertheless, efforts should be directed to overcome this scientific division, in order to develop a pluralist and interdisciplinary national science, committed to the health care realities of our country.

  4. Basic research in crystalline and noncrystalline ceramic systems. Annual report, May 1, 1975--April 1, 1976

    International Nuclear Information System (INIS)

    Activities in research programs on ceramics are reported in sections on electric conductivity and dielectric properties, microstructure and properties, ion transport and diffusion, defect interactions and grain boundary phenomena, and future developments

  5. Practical research: a basic outline for mid-level eye personnel

    Directory of Open Access Journals (Sweden)

    C Patricia Fathers

    2007-03-01

    Full Text Available Research plays an important role in the work of mid-level eye health personnel who want to provide the best possible care based on accurate and relevant evidence. For example, Isaac Baba, eye co-ordinator of Bawku Presbyterian Hospital in Ghana, describes a simple research exercise to understand and improve patient satisfaction with the eye care offered in the outpatient department.

  6. INTEGRATING BASIC SCIENCES INTO GLOBAL HEALTH BY IMPLEMENTING THE TRANSLATIONAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Muhamad Nurhalim Shahib

    2013-06-01

    Full Text Available An emphasize on herbal medicine in cancer therapy is also included as an example of translational research implementation. A translational research in Faculty of Medicine, Universitas Padjajaran, has been conducted to develop a novel genomic approach (herbal genomic on herbal crude extracts. This study focuses on the effects of the extracts on specific gene expressions. In this aspect, the concept of molecular targets is slightly different from pharmaceutical approaches that aim to find compounds that interact with a specific molecule or macromolecule with known function. In this research strategy, the herbal genomic approaches involve screening of herbal extracts that affect particular gene expression related to cell responses rather than a single proteins. The determination of herbal concentration is based on differential gene expression before and after treatment which is analyzed by real time PCR. The results are being compared to the existing small molecule (active molecule on the gene expressions. All these academic activities require biomedical research workforce to implement the translational research which, in the Faculty of Medicine, Universitas Padjadjaran, is fulfilled by involving the postgraduate students. New crude extract formulation plus specific gene expression profile is a concept required for developing chemotherapeutic agent in Indonesia. Hopefully, this review can support increased cooperation between hospital and academic institutions in implementing translational research in Indonesia.

  7. Impacts of Social-Emotional Curricula on Three-Year-Olds: Exploratory Findings from the Head Start CARES Demonstration. Research Snapshot. OPRE Report 2014-78

    Science.gov (United States)

    Hsueh, JoAnn; Lowenstein, Amy E.; Morris, Pamela; Mattera, Shira K.; Bangser, Michael

    2014-01-01

    This report presents exploratory impact findings for 3-year-olds from the Head Start CARES demonstration, a large-scale randomized controlled trial implemented in Head Start centers for one academic year across the country. The study was designed primarily to test the effects of the enhancements on 4-year-olds, but it also provides an opportunity…

  8. Methodological exploratory study applied to occupational epidemiology

    International Nuclear Information System (INIS)

    The utilization of epidemiologic methods and techniques has been object of practical experimentation and theoretical-methodological reflection in health planning and programming process. Occupational Epidemiology is the study of the causes and prevention of diseases and injuries from exposition and risks in the work environment. In this context, there is no intention to deplete such a complex theme but to deal with basic concepts of Occupational Epidemiology, presenting the main characteristics of the analysis methods used in epidemiology, as investigate the possible determinants of exposition (chemical, physical and biological agents). For this study, the social-demographic profile of the IPEN-CNEN/SP work force was used. The knowledge of this reference population composition is based on sex, age, educational level, marital status and different occupations, aiming to know the relation between the health aggravating factors and these variables. The methodology used refers to a non-experimental research based on a theoretical methodological practice. The work performed has an exploratory character, aiming a later survey of indicators in the health area in order to analyze possible correlations related to epidemiologic issues. (author)

  9. Development of a control alternative for the citrus fruit borer, Ecdytolopha aurantiana (Lepidoptera, Tortricidae): from basic research to the grower

    International Nuclear Information System (INIS)

    All research steps, developed from 1995 to 2000, to synthesize the sex pheromone of Ecdytolopha aurantiana (Lima, 1927) are described, in order to monitoring this pest that causes losses in the order of 50 million dollars per year to citriculture in the State of Sao Paulo. The basic researches conducted are described, including the development of an artificial diet for the insect, the study of its temperature and humidity requirements, behavioral studies, and synthesis of the male-attracting substance up to the formulation and distribution of the pheromone to the grower, by means of its commercialization. It is a case of success, at a cost of 50 thousand dollars, involving inter- and multidisciplinary researches, which can be adopted to other insect pests in the country. (author)

  10. Development of a control alternative for the citrus fruit borer, Ecdytolopha aurantiana (Lepidoptera, Tortricidae): from basic research to the grower

    Energy Technology Data Exchange (ETDEWEB)

    Parra, Jose Roberto P.; Bento, Jose Mauricio S. [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Entomologia, Fitopatologia e Zoologia Agricola], e-mail: jrpparra@esalq.usp.br; Garcia, Mauro S. [Universidade Federal de Pelotas (UFPel), RS (Brazil); Yamamoto, Pedro T. [Fundo de Defesa da Citricultura (Fundecitrus), Araraquara, SP (Brazil); Vilela, Evaldo F. [Universidade Federal de Vicosa (UFV), MG (Brazil). Dept. de Biologia Animal; Leal, Walter S. [University of California, Davis, CA (Brazil). Dept. of Entomology

    2004-12-15

    All research steps, developed from 1995 to 2000, to synthesize the sex pheromone of Ecdytolopha aurantiana (Lima, 1927) are described, in order to monitoring this pest that causes losses in the order of 50 million dollars per year to citriculture in the State of Sao Paulo. The basic researches conducted are described, including the development of an artificial diet for the insect, the study of its temperature and humidity requirements, behavioral studies, and synthesis of the male-attracting substance up to the formulation and distribution of the pheromone to the grower, by means of its commercialization. It is a case of success, at a cost of 50 thousand dollars, involving inter- and multidisciplinary researches, which can be adopted to other insect pests in the country. (author)

  11. Basic to translational research in dementia: meeting report from the Alzheimer’s Research UK Conference 2014

    OpenAIRE

    Sancho, Rosa M.; Ridley, Simon H.; Phipps, Laura E.; Karran, Eric

    2014-01-01

    This report summarizes the findings presented at the Alzheimer’s Research UK Conference, which was held in Oxford on 25 and 26 March 2014 and which provided an overview of current dementia research from fundamental disease mechanisms to clinical studies.

  12. User Facilities of the Office of Basic Energy Sciences: A National Resource for Scientific Research

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-01-01

    The BES user facilities provide open access to specialized instrumentation and expertise that enable scientific users from universities, national laboratories, and industry to carry out experiments and develop theories that could not be done at their home institutions. These forefront research facilities require resource commitments well beyond the scope of any non-government institution and open up otherwise inaccessible facets of Nature to scientific inquiry. For approved, peer-reviewed projects, instrument time is available without charge to researchers who intend to publish their results in the open literature. These large-scale user facilities have made significant contributions to various scientific fields, including chemistry, physics, geology, materials science, environmental science, biology, and biomedical science. Over 16,000 scientists and engineers.pdf file (27KB) conduct experiments at BES user facilities annually. Thousands of other researchers collaborate with these users and analyze the data measured at the facilities to publish new scientific findings in peer-reviewed journals.

  13. Organic solar cell exploratory research

    Science.gov (United States)

    Yalenty, S. J.

    1975-01-01

    Principles governing the photovoltaic effect in organic materials on the molecular level are studied and applied to the design and fabrication of laboratory devices having a photovoltaic organic polymer film as their key element. Progress to date has been in three areas: (1) materials synthesis; (2) apparatus development; and (3) ultra-thin film fabrication.

  14. Higher Education and Research: The Basic Functions of the Modern University.

    Science.gov (United States)

    Fischer-Appelt, Peter

    1984-01-01

    Research appeared as a central function of the university only in 1810 with the foundation of the University of Berlin. Today, the scientist's responsibility is to understand and control the process of discovery within the social context, especially through international dialog and cooperation. (MSE)

  15. Basic Research Needs for Geosciences: Facilitating 21st Century Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    DePaolo, D. J.; Orr, F. M.; Benson, S. M.; Celia, M.; Felmy, A.; Nagy, K. L.; Fogg, G. E.; Snieder, R.; Davis, J.; Pruess, K.; Friedmann, J.; Peters, M.; Woodward, N. B.; Dobson, P.; Talamini, K.; Saarni, M.

    2007-06-01

    To identify research areas in geosciences, such as behavior of multiphase fluid-solid systems on a variety of scales, chemical migration processes in geologic media, characterization of geologic systems, and modeling and simulation of geologic systems, needed for improved energy systems.

  16. Programme Implementation in Social and Emotional Learning: Basic Issues and Research Findings

    Science.gov (United States)

    Durlak, Joseph A.

    2016-01-01

    This paper discusses the fundamental importance of achieving quality implementation when assessing the impact of social and emotional learning interventions. Recent findings in implementation science are reviewed that include a definition of implementation, its relation to programme outcomes, current research on the factors that affect…

  17. Proceedings of the meeting on engineering and technology in basic research

    International Nuclear Information System (INIS)

    This is the report of the technical research meeting of National Laboratory for High Energy Physics held at the Laboratory in Tsukuba on February 6 and 7, 1992. The gists of 16 papers on manufacturing techniques, 15 papers on low temperature technologies, 19 papers on measurement and control technologies, 16 papers on computer and data processing technologies and 20 papers on apparatus technologies are collected in this report. (K.I.)

  18. Basic Research on Selecting ISDC Activity for Decommissioning Costing in KRR-2 Decommissioning Project Experience Data

    Energy Technology Data Exchange (ETDEWEB)

    Song, Chan-Ho; Park, Hee-Seong; Jin, Hyung-Gon; Park, Seung-Kook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    KAERI is performing research for calculation of expected time of a decommissioning work and evaluation of decommissioning cost and this research calculate a decommissioning work unit productivity based on the experience data of decommissioning activity for KRR-2. The KAERI be used to calculate the decommissioning cost and manage the experience data from the decommissioning activity through the Decommissioning Information Management System (DECOMMIS), Decommissioning Facility Characterization DB System (DEFACS), and Decommissioning Work-unit Productivity Calculation System (DEWOCS). In this paper, the methodology was presented how select the ISDC activities in dismantling work procedures of a 'removal of radioactive concrete'. The reason to select the 'removal of radioactive concrete' is main key activity and generates the amount of radioactive waste. This data will take advantage of the cost estimation after the code for the selected items derived ISDC. There are various efforts for decommissioning costing in each country. In particular, OECD/NEA recommends decommissioning cost estimation using the ISDC and IAEA provides for Cost Estimation for Research Reactors in Excel (CERREX) program that anyone is easy to use the cost evaluation from a limited decommissioning experience in domestic. In the future, for the decommissioning cost evaluation, the ISDC will be used more widely in a strong position. This paper has described a method for selecting the ISDC item from the actual dismantling work procedures.

  19. Basic Research of Intrinsic Tamper Indication Markings Defined by Pulsed Laser Irradiation (Quad Chart).

    Energy Technology Data Exchange (ETDEWEB)

    Moody, Neville R. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2015-08-01

    Objective: We will research how short (ns) and ultrashort (fs) laser pulses interact with the surfaces of various materials to create complex color layers and morphological patterns. Method: We are investigating the site-specific, formation of microcolor features. Also, research includes a fundamental study of the physics underlying periodic ripple formation during femtosecond laser irradiation. Status of effort: Laser induced color markings were demonstrated on an increased number of materials (including metal thin films) and investigated for optical properties and microstructure. Technology that allows for marking curved surfaces (and large areas) has been implemented. We have used electro-magnetic solvers to model light-solid interactions leading to periodic surface ripple patterns. This includes identifying the roles of surface plasmon polaritons. Goals/Milestones: Research corrosion resistance of oxide color markings (salt spray, fog, polarization tests); Through modeling, investigate effects of multi-source scattering and interference on ripple patterns; Investigate microspectrophotometry for mapping color; and Investigate new methods for laser color marking curved surfaces and large areas.

  20. Basic research on separation control of long life nuclides in fuel reprocessing processes

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Atsuyuki; Usami, Go [Tokyo Univ. (Japan). Faculty of Engineering; Maeda, Mitsuru; Fujine, Sachio; Uchiyama, Gunzo; Kihara, Takehiro; Asakura, Toshihide; Hotoku, Shinobu

    1996-01-01

    The behavior of technetium (Tc) in nuclear fuel reprocessing processes has become the subject to be elucidated in the transition to distribution process by coextraction and the catalytic action in distribution process. In order to forecast or control the behavior of Tc in reprocessing processes, it is necessary to understand that at which valence Tc exists stably in respective processes. Tc is stable at 7 valence in nitric acid solution expected in reprocessing. In this research, the reaction speed of the oxidation and reduction reactions of rhenium (Re) which simulates Tc was measured by laser Raman spectroscopy which can do high speed analysis of valence. The experimental method is explained. The Raman spectra of Re in the experimental system of this research were measured in perchloric acid solution and nitric acid solution, and compared with the values in literatures. As the result, the validity of this research was assured. It was confirmed that Re(7) was not reduced by sulfamic acid and ascorbic acid. Re(7) was reduced by thiocyanic acid once, but was oxidized again by the reaction of thiocyanic acid and nitric acid. (K.I.)

  1. The chain reaction: a golden jubilee commemorative volume on research in basic sciences at DAE Institutions. V. 1

    International Nuclear Information System (INIS)

    This book has been chosen to metaphorically reflect how research in basic sciences in various institutions of the Department of Atomic Energy (DAE) has evolved over the years, closely mimicking what goes on in a nuclear chain reactor. Since, for harnessing atomic energy for peaceful uses, nuclear physics and atomic physics are the two core activities, work was undertaken in these areas during initial days at the Tata Institute of Fundamental Research. These activities then promoted the growth of major programmes in a number of areas, such as, reactor physics, accelerator physics, condensed matter physics and materials science, theoretical physics and mathematical physics, astronomy and astrophysics, laser and plasma physics, radiation chemistry, photochemistry, chemical dynamics, nuclear chemistry, radiation biology and health sciences, molecular and cellular biology, structural biology and biophysics, agriculture and food sciences etc. In turn, all these programmes have been fostering the growth in several other domains of science, engineering and technology

  2. Basic research in crystalline and noncrystalline ceramic systems. Annual report, August 1, 1978-October 31, 1979

    International Nuclear Information System (INIS)

    Research is reported in optical and dielectric properties of MgO, aluminium oxide, and y-doped UO2; kinetic studies of MgO, magnesium hydroxide, KCl-doped SrCl2, KCl, and Al2O3; defect structures of MgO, ZnO-Bi2O3, SiC, Sc2O3, Al2O3, Cr2O3, and SiO2; sintering studies of alumina; and mechanical properties of UO2, Al2O3, and creep in W

  3. [Asthma Update 2015--What Cell Biology in Basic Pulmonary Research Can Offer to the Pneumologist].

    Science.gov (United States)

    Wegmann, M; Fehrenbach, H; Krauss-Etschmann, S

    2016-02-01

    Bronchial asthma is one of the most common chronic inflammatory diseases world-wide causing an enormous socio-economic burden especially in industrialized countries. Currently, asthma is increasingly considered to be a poly-symptomatic disease comprising a variety of different asthma phenotypes and endotypes. This heterogeneity of asthma explains why the standard treatment with corticosteroids and β-agonists cannot achieve full symptom control in all cases, especially not during acute exacerbations. Therefore, current asthma research focuses on primary prevention of asthma as well as on novel approaches towards a phenotype- and endotype-specific asthma therapy.

  4. Basic research with view to the development of new techniques of wood chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Wienhaus, O.; Koch, H.; Schiene, R.; Fischer, F.

    1987-01-01

    The paper provides an overview of research in the areas wood pyrolysis (smoldering behaviour of the components of tree material, production of activated coal from coke from mixed chipwood of pine, process for drying, smoldering, and partial gasification of wood in a reactor, wood tar analyses, phenolic-resin glues on the basis of wood tar), utilization of lignin (Knowledge of material composition, utilization as a coking auxiliary, chemical conversion by hydrogenolysis and oxydative ammonolysis) and substances extracted from wood (tall oil production and upgrading, manufacture of paper glues from tall oil resin, production of ..beta..-sitosterol).

  5. Stimulating translational research

    DEFF Research Database (Denmark)

    Bentires-Alj, Mohamed; Rajan, Abinaya; van Harten, Wim;

    2015-01-01

    Translational research leaves no-one indifferent and everyone expects a particular benefit. We as EU-LIFE (www.eu-life.eu), an alliance of 13 research institutes in European life sciences, would like to share our experience in an attempt to identify measures to promote translational research with...... without undermining basic exploratory research and academic freedom.......Translational research leaves no-one indifferent and everyone expects a particular benefit. We as EU-LIFE (www.eu-life.eu), an alliance of 13 research institutes in European life sciences, would like to share our experience in an attempt to identify measures to promote translational research...

  6. Wavelet basics

    CERN Document Server

    Chan, Y T

    1995-01-01

    Since the study of wavelets is a relatively new area, much of the research coming from mathematicians, most of the literature uses terminology, concepts and proofs that may, at times, be difficult and intimidating for the engineer. Wavelet Basics has therefore been written as an introductory book for scientists and engineers. The mathematical presentation has been kept simple, the concepts being presented in elaborate detail in a terminology that engineers will find familiar. Difficult ideas are illustrated with examples which will also aid in the development of an intuitive insight. Chapter 1 reviews the basics of signal transformation and discusses the concepts of duals and frames. Chapter 2 introduces the wavelet transform, contrasts it with the short-time Fourier transform and clarifies the names of the different types of wavelet transforms. Chapter 3 links multiresolution analysis, orthonormal wavelets and the design of digital filters. Chapter 4 gives a tour d'horizon of topics of current interest: wave...

  7. Use of plant bioassays in homeopathic basic research – a systematic review

    Directory of Open Access Journals (Sweden)

    Ursula Wolf

    2012-09-01

    Full Text Available Background: Experimental research on the effects of treatments with homeopathic preparations on plants was last reviewed in 1990. Aims: The objective was to compile a systematic literature review on plant bioassays in homeopathic basic research using predefined criteria. Methods: Literature search was carried out on publications that reported experiments with homeopathic preparations on whole plants, seeds, plant parts or cells from 1920 to 2010, in healthy, abiotically or biotically stressed conditions. Outcomes had to be measured by established state-of-the-art procedures and statistically evaluated. Using a Manuscript Information Score (MIS those publications were identified that provided sufficient information for proper interpretation (MIS > 5. Further evaluation focused on the use of adequate controls to investigate specific effects of homeopathic preparations and on the use of systematic negative control experiments to ensure proper system performance. Results: A total of 157 publications with plants were identified [1–3]. The 157 publications described a total of 167 experimental studies. 84 studies included statistics and 48 had a MIS > 5 allowing proper interpretation. 29 studies were identified with adequate controls to identify specific effects of homeopathic preparations, reporting significant effects of decimal and centesimal homeopathic potencies, including dilution levels beyond Avogadro’s number. Studies that tested series of consecutive potency levels reported a non-linear and discontinuous relation between effect and potency level. There were many individual studies with diverse methods and very few replication trials. 10 studies reported use of systematic negative control experiments, yielding evidence for the stability of the experimental set-up. Conclusions: Plant models appear to be a useful approach to investigate basic research questions on

  8. Basic Research and Development Effort to Design a Micro Nuclear Power Plant for Brazilian Space Applications

    Science.gov (United States)

    Guimares, L. N. F.; Camillo, G. P.; Placco, G. M.; Barrios, G., A., Jr.; Do Nascimento, J. A.; Borges, E. M.; De Castro Lobo, P. D.

    For some years the Nuclear Energy Division of the Institute for Advanced Studies is conducting the TERRA (Portuguese abbreviation for advanced fast reactor technology) project. This project aims at research and development of the key issues related with nuclear energy applied to space technology. The purpose of this development is to allow future Brazilian space explorers the access of a good and reliable heat, power and/or propulsion system based on nuclear energy. Efforts are being made in fuel and nuclear core design, designing and building a closed Brayton cycle loop for energy conversion, heat pipe systems research for passive space heat rejection, developing computational programs for thermal loop safety analysis and other technology that may be used to improve efficiency and operation. Currently there is no specific mission that requires these technology development efforts; therefore, there is a certain degree of freedom in the organization and development efforts. This paper will present what has been achieved so far, what is the current development status, where efforts are heading and a proposed time table to meet development objectives.

  9. Basic Principles of the Activity and Synergetic Approach as a Means of Interdisciplinary Research

    Directory of Open Access Journals (Sweden)

    Bolsunovskaya L.M.

    2016-01-01

    Full Text Available The paper considers the problem of interdisciplinarity as the main tendency of today’s science to unite the methodology and terminology and adapt them to any academic field in order to achieve more objective results in the study of complex phenomena. This article is a descriptive one and it deals with problems of terms’ interpretations and their adaptation to the anthropocentric research viewed by scientists of different academic schools. The main idea of the article is to find the most relevant and systemic definition of the given terms, which could be used as a tool in further linguistic analysis applied to the coming research of the authors. Special attention is paid to the description of the Activity Theory from different aspects of its interpretation: psychological, sociological, linguistic; to the explanation of the correlation between the epistemic structure of knowledge and an open non-linear synergetic bilateral (conceptual and lexical-semantic system influenced and motivated by processual factors to evolution in the modern discourse as the communicative activity of the interpreter and the constructor of discourse.

  10. Education in Old Age: An Exploratory Study

    Science.gov (United States)

    Luppi, Elena

    2009-01-01

    The following work outlines an analysis of education initiatives aimed at the elderly. It examines the characteristics of the old aged learner, his/her "educability" and the foundations for an educational approach for this age group. These theoretical assumptions form the basis of this research: an exploratory study into various educational and…

  11. [Psychoanalysis and early childhood research. Some basic topics of the debate].

    Science.gov (United States)

    Dornes, M

    1993-12-01

    In Dornes' view it is time for psychoanalytic development psychology to stand back from its preoccupation with the reconstructed child and gain access to the real child via direct observation, thus re-establishing contact with the state of research in neighbouring disciplines. Such direct observation would both stimulate a review of the cogency of the symbiosis and borderline theories of normal early development and question the assumption of lack of psychic differentiation in newborn children. So far, the author contends, psychoanalytic theory has both underestimated and overestimated the abilities of infants, ascribing to them in the latter case the capacity for complicated psychic operations (hallucinatory wish fulfillment, grandeur fantasies, projective identifications) which are in fact beyond their powers. PMID:8310132

  12. Basics of Fusion-Fissison Research Facility (FFRF) as a Fusion Neutron Source

    Energy Technology Data Exchange (ETDEWEB)

    Leonid E. Zakharov

    2011-06-03

    FFRF, standing for the Fusion-Fission Research Facility represents an option for the next step project of ASIPP (Hefei, China) aiming to a first fusion-fission multifunctional device [1]. FFRF strongly relies on new, Lithium Wall Fusion plasma regimes, the development of which has already started in the US and China. With R/a=4/1m/m, Ipl=5 MA, Btor=4-6 T, PDT=50- 100 MW, Pfission=80-4000MW, 1 m thick blanket, FFRF has a unique fusion mission of a stationary fusion neutron source. Its pioneering mission of merging fusion and fission consists in accumulation of design, experimental, and operational data for future hybrid applications.

  13. Progress report to the Department of Energy in support of basic energy and policy research

    International Nuclear Information System (INIS)

    This progress report describes the accomplishments of the first and second years of the three year institutional grant received from the Department of Energy and describes the activities now envisioned for year three. Attachments detailing the highlights of the first and second years' accomplishments are included. Research areas include: light path of carbon reduction in photosynthesis; heat transfer in coal-ash slags; mechanism of plant cell enlargement in Gymnosperms, emulsion stability in enhanced oil recovery; selective transfer phenomenon in friction and wear; conceptual design of the Purdue Compact Torus/Passive Liner Fusion Reactor; integration of farm level alcohol production consistent with the economic and labor constraints of a farming operation, and newsmedia coverage of selected energy policy proposals. Separate abstracts have been prepared for selected attachments for inclusion in the Energy Data Base

  14. Research into the Application of ADO.NET in Visual Basic.NET%ADO.NET及在Visual Basic.NET窗体中的应用研究

    Institute of Scientific and Technical Information of China (English)

    袁小玲

    2002-01-01

    ADO.NET是.NET框架中推出的一种基于XML的全新的数据访问技术.文章首先分析了ADO.NET的基本原理和DataSet的使用方法,然后探讨了Windows窗体中使用ADO.NET的技巧,最后给出了在Visual Basic .NET的Windows窗体中使用ADO.NET的一个完整示例.从而为在.NET框架中开发数据库应用系统提供参考.

  15. A Track Record on SHOX: From Basic Research to Complex Models and Therapy.

    Science.gov (United States)

    Marchini, Antonio; Ogata, Tsutomu; Rappold, Gudrun A

    2016-08-01

    SHOX deficiency is the most frequent genetic growth disorder associated with isolated and syndromic forms of short stature. Caused by mutations in the homeobox gene SHOX, its varied clinical manifestations include isolated short stature, Léri-Weill dyschondrosteosis, and Langer mesomelic dysplasia. In addition, SHOX deficiency contributes to the skeletal features in Turner syndrome. Causative SHOX mutations have allowed downstream pathology to be linked to defined molecular lesions. Expression levels of SHOX are tightly regulated, and almost half of the pathogenic mutations have affected enhancers. Clinical severity of SHOX deficiency varies between genders and ranges from normal stature to profound mesomelic skeletal dysplasia. Treatment options for children with SHOX deficiency are available. Two decades of research support the concept of SHOX as a transcription factor that integrates diverse aspects of bone development, growth plate biology, and apoptosis. Due to its absence in mouse, the animal models of choice have become chicken and zebrafish. These models, therefore, together with micromass cultures and primary cell lines, have been used to address SHOX function. Pathway and network analyses have identified interactors, target genes, and regulators. Here, we summarize recent data and give insight into the critical molecular and cellular functions of SHOX in the etiopathogenesis of short stature and limb development. PMID:27355317

  16. Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.

    Directory of Open Access Journals (Sweden)

    Sebastian Schaaf

    Full Text Available Human embryonic stem cell (hESC progenies hold great promise as surrogates for human primary cells, particularly if the latter are not available as in the case of cardiomyocytes. However, high content experimental platforms are lacking that allow the function of hESC-derived cardiomyocytes to be studied under relatively physiological and standardized conditions. Here we describe a simple and robust protocol for the generation of fibrin-based human engineered heart tissue (hEHT in a 24-well format using an unselected population of differentiated human embryonic stem cells containing 30-40% α-actinin-positive cardiac myocytes. Human EHTs started to show coherent contractions 5-10 days after casting, reached regular (mean 0.5 Hz and strong (mean 100 µN contractions for up to 8 weeks. They displayed a dense network of longitudinally oriented, interconnected and cross-striated cardiomyocytes. Spontaneous hEHT contractions were analyzed by automated video-optical recording and showed chronotropic responses to calcium and the β-adrenergic agonist isoprenaline. The proarrhythmic compounds E-4031, quinidine, procainamide, cisapride, and sertindole exerted robust, concentration-dependent and reversible decreases in relaxation velocity and irregular beating at concentrations that recapitulate findings in hERG channel assays. In conclusion this study establishes hEHT as a simple in vitro model for heart research.

  17. A Track Record on SHOX: From Basic Research to Complex Models and Therapy

    Science.gov (United States)

    Marchini, Antonio; Ogata, Tsutomu

    2016-01-01

    SHOX deficiency is the most frequent genetic growth disorder associated with isolated and syndromic forms of short stature. Caused by mutations in the homeobox gene SHOX, its varied clinical manifestations include isolated short stature, Léri-Weill dyschondrosteosis, and Langer mesomelic dysplasia. In addition, SHOX deficiency contributes to the skeletal features in Turner syndrome. Causative SHOX mutations have allowed downstream pathology to be linked to defined molecular lesions. Expression levels of SHOX are tightly regulated, and almost half of the pathogenic mutations have affected enhancers. Clinical severity of SHOX deficiency varies between genders and ranges from normal stature to profound mesomelic skeletal dysplasia. Treatment options for children with SHOX deficiency are available. Two decades of research support the concept of SHOX as a transcription factor that integrates diverse aspects of bone development, growth plate biology, and apoptosis. Due to its absence in mouse, the animal models of choice have become chicken and zebrafish. These models, therefore, together with micromass cultures and primary cell lines, have been used to address SHOX function. Pathway and network analyses have identified interactors, target genes, and regulators. Here, we summarize recent data and give insight into the critical molecular and cellular functions of SHOX in the etiopathogenesis of short stature and limb development. PMID:27355317

  18. A Track Record on SHOX: From Basic Research to Complex Models and Therapy.

    Science.gov (United States)

    Marchini, Antonio; Ogata, Tsutomu; Rappold, Gudrun A

    2016-08-01

    SHOX deficiency is the most frequent genetic growth disorder associated with isolated and syndromic forms of short stature. Caused by mutations in the homeobox gene SHOX, its varied clinical manifestations include isolated short stature, Léri-Weill dyschondrosteosis, and Langer mesomelic dysplasia. In addition, SHOX deficiency contributes to the skeletal features in Turner syndrome. Causative SHOX mutations have allowed downstream pathology to be linked to defined molecular lesions. Expression levels of SHOX are tightly regulated, and almost half of the pathogenic mutations have affected enhancers. Clinical severity of SHOX deficiency varies between genders and ranges from normal stature to profound mesomelic skeletal dysplasia. Treatment options for children with SHOX deficiency are available. Two decades of research support the concept of SHOX as a transcription factor that integrates diverse aspects of bone development, growth plate biology, and apoptosis. Due to its absence in mouse, the animal models of choice have become chicken and zebrafish. These models, therefore, together with micromass cultures and primary cell lines, have been used to address SHOX function. Pathway and network analyses have identified interactors, target genes, and regulators. Here, we summarize recent data and give insight into the critical molecular and cellular functions of SHOX in the etiopathogenesis of short stature and limb development.

  19. GANIL: a basic nuclear installation dedicated to research - 'ACROnic du nucleaire' nr 90, September 2010

    International Nuclear Information System (INIS)

    GANIL stands for Grand Accelerateur National d'Ions Lourds (Large National accelerator of heavy ions). It is located in Caen. A new installation for the production of radioactive ions (SPIRAL2) is planned within this research facility. This document briefly describes the use of ion beams to explore matter, and the purpose of GANIL, SPIRAL and SPIRAL2. The construction of this last equipment induces new radiation protection and safety issues which are herein discussed: matter confinement, protection of personnel, waste management (dismantling, storage and transport), and impact of releases on the environment. Annual authorization for gaseous releases and equivalent dose limitations are indicated. The document presents the action of the local information commission (CLI) which has been created in relationship with this nuclear installation, and comments the answers given by the GSIEN (Group of scientists for information on nuclear energy) to questions asked by the CLI about the need for a release authorization, about specified levels, about the waste issue, about incident or accident scenarios, about possibilities to optimize the survey system. A last part reports the CLI's opinion on the public inquiry made about the SPIRAL2 project

  20. The Path to Sustainable Nuclear Energy. Basic and Applied Research Opportunities for Advanced Fuel Cycles, September 12-14, 2005

    International Nuclear Information System (INIS)

    The objective of this report is to identify new basic science that will be the foundation for advances in nuclear fuel-cycle technology in the near term, and for changing the nature of fuel cycles and of the nuclear energy industry in the long term. The goals are to enhance the development of nuclear energy, to maximize energy production in nuclear reactor parks, and to minimize radioactive wastes, other environmental impacts, and proliferation risks. The limitations of the once-through fuel cycle can be overcome by adopting a closed fuel cycle, in which the irradiated fuel is reprocessed and its components are separated into streams that are recycled into a reactor or disposed of in appropriate waste forms. The recycled fuel is irradiated in a reactor, where certain constituents are partially transmuted into heavier isotopes via neutron capture or into lighter isotopes via fission. Fast reactors are required to complete the transmutation of long-lived isotopes. Closed fuel cycles are encompassed by the Department of Energy?s Advanced Fuel Cycle Initiative (AFCI), to which basic scientific research can contribute. Two nuclear reactor system architectures can meet the AFCI objectives: a ?single-tier? system or a ?dual-tier? system. Both begin with light water reactors and incorporate fast reactors. The ?dual-tier? systems transmute some plutonium and neptunium in light water reactors and all remaining transuranic elements (TRUs) in a closed-cycle fast reactor. Basic science initiatives are needed in two broad areas: ? Near-term impacts that can enhance the development of either ?single-tier? or ?dual-tier? AFCI systems, primarily within the next 20 years, through basic research. Examples: Dissolution of spent fuel, separations of elements for TRU recycling and transmutation Design, synthesis, and testing of inert matrix nuclear fuels and non-oxide fuels Invention and development of accurate on-line monitoring systems for chemical and nuclear species in the nuclear

  1. Proceeding of the Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology. Part I : Physics, Reactor Physics and Nuclear Instrumentation

    International Nuclear Information System (INIS)

    Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology is a routine activity was held by PPNY BATAN for monitoring the research Activity which achieved in BATAN. The Proceeding contains a proposal about basic which has physics; reactor physics and nuclear instrumentation. This proceedings is the first part from two part which published in series. There are 33 articles which have separated index

  2. Summary on the researcher exchanges from FY2006-2011 from Chinese side (basic research of nuclear fusion reactor engineering)20-A,D,E,F

    International Nuclear Information System (INIS)

    From 2006-2010, there are many research activities carried out in the field of “basic research of nuclear fusion reactor engineering” between Japan and China. This field includes: “study on reduced activation material for fusion”, “development of superconducting key technology for advanced fusion reactor”, “study of tritium behavior in solid and liquid breed material”, “advanced reactor design and technological integration”. More than 10 researchers from China visited National Institute for Fusion Science and other Japanese institute and university every year. Several JSPS-CAS CUP Program Seminars were held in China. Based on EAST, LHD operation, JT-60 upgrade construction, ITER project, demonstration fusion reactor design, we can foresee that many co-operations can be carried out widely in this field. (author)

  3. Performance-driven facial animation: basic research on human judgments of emotional state in facial avatars.

    Science.gov (United States)

    Rizzo, A A; Neumann, U; Enciso, R; Fidaleo, D; Noh, J Y

    2001-08-01

    three-dimensional avatar using a performance-driven facial animation (PDFA) system developed at the University of Southern California Integrated Media Systems Center. PDFA offers a means for creating high-fidelity visual representations of human faces and bodies. This effort explores the feasibility of sensing and reproducing a range of facial expressions with a PDFA system. In order to test concordance of human ratings of emotional expression between video and avatar facial delivery, we first had facial model subjects observe stimuli that were designed to elicit naturalistic facial expressions. The emotional stimulus induction involved presenting text-based, still image, and video clips to subjects that were previously rated to induce facial expressions for the six universals2 of facial expression (happy, sad, fear, anger, disgust, and surprise), in addition to attentiveness, puzzlement and frustration. Videotapes of these induced facial expressions that best represented prototypic examples of the above emotional states and three-dimensional avatar animations of the same facial expressions were randomly presented to 38 human raters. The raters used open-end, forced choice and seven-point Likert-type scales to rate expression in terms of identification. The forced choice and seven-point ratings provided the most usable data to determine video/animation concordance and these data are presented. To support a clear understanding of this data, a website has been set up that will allow readers to view the video and facial animation clips to illustrate the assets and limitations of these types of facial expression-rendering methods (www. USCAvatars.com/MMVR). This methodological first step in our research program has served to provide valuable human user-centered feedback to support the iterative design and development of facial avatar characteristics for expression of emotional communication. PMID:11708727

  4. Performance-driven facial animation: basic research on human judgments of emotional state in facial avatars.

    Science.gov (United States)

    Rizzo, A A; Neumann, U; Enciso, R; Fidaleo, D; Noh, J Y

    2001-08-01

    three-dimensional avatar using a performance-driven facial animation (PDFA) system developed at the University of Southern California Integrated Media Systems Center. PDFA offers a means for creating high-fidelity visual representations of human faces and bodies. This effort explores the feasibility of sensing and reproducing a range of facial expressions with a PDFA system. In order to test concordance of human ratings of emotional expression between video and avatar facial delivery, we first had facial model subjects observe stimuli that were designed to elicit naturalistic facial expressions. The emotional stimulus induction involved presenting text-based, still image, and video clips to subjects that were previously rated to induce facial expressions for the six universals2 of facial expression (happy, sad, fear, anger, disgust, and surprise), in addition to attentiveness, puzzlement and frustration. Videotapes of these induced facial expressions that best represented prototypic examples of the above emotional states and three-dimensional avatar animations of the same facial expressions were randomly presented to 38 human raters. The raters used open-end, forced choice and seven-point Likert-type scales to rate expression in terms of identification. The forced choice and seven-point ratings provided the most usable data to determine video/animation concordance and these data are presented. To support a clear understanding of this data, a website has been set up that will allow readers to view the video and facial animation clips to illustrate the assets and limitations of these types of facial expression-rendering methods (www. USCAvatars.com/MMVR). This methodological first step in our research program has served to provide valuable human user-centered feedback to support the iterative design and development of facial avatar characteristics for expression of emotional communication.

  5. The Renin-Angiotensin System Modulates Inflammatory Processes in Atherosclerosis: Evidence from Basic Research and Clinical Studies

    Directory of Open Access Journals (Sweden)

    Fabrizio Montecucco

    2009-01-01

    Full Text Available Recent evidence shows that the renin-angiotensin system is a crucial player in atherosclerotic processes. The regulation of arterial blood pressure was considered from its first description of the main mechanism involved. Vasoconstriction (mediated by angiotensin II and salt and water retention (mainly due to aldosterone were classically considered as pivotal proatherosclerotic activities. However, basic research and animal studies strongly support angiotensin II as a proinflammatory mediator, which directly induces atherosclerotic plaque development and heart remodeling. Furthermore, angiotensin II induces proatherosclerotic cytokine and chemokine secretion and increases endothelial dysfunction. Accordingly, the pharmacological inhibition of the renin-angiotensin system improves prognosis of patients with cardiovascular disease even in settings of normal baseline blood pressure. In the present review, we focused on angiotensin-convertingenzyme (ACE inhibitors, angiotensin II receptor blockers (ARBs, and renin inhibitors to update the direct activities of the renin-angiotensin system in inflammatory processes governing atherosclerosis.

  6. The Basic Research on Public Diplomacy%有关公共外交研究的几个问题

    Institute of Scientific and Technical Information of China (English)

    金正昆; 黄达

    2012-01-01

    As one of the new types of diplomacy,public diplomacy is being highly focused. The authors of this article stre- amline the existing fruits in the area of public diplomacy research and put forward his understanding of the definition,theo- retical sources, basic features and functions of the public diplomacy.%作为非传统外交的新形式之一,公共外交目前颇受关注。本文对近年来有关公共外交的研究成果做了较为系统的梳理,并着重对其提出与具体界定、理论来源、基本特征与主要功能进行了探讨。

  7. 18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

  8. Artificially induced epithelial-mesenchymal transition in surgical subjects: its implications in clinical and basic cancer research.

    Directory of Open Access Journals (Sweden)

    Kazuhiko Aoyagi

    Full Text Available BACKGROUND: Surgical samples have long been used as important subjects for cancer research. In accordance with an increase of neoadjuvant therapy, biopsy samples have recently become imperative for cancer transcriptome. On the other hand, both biopsy and surgical samples are available for expression profiling for predicting clinical outcome by adjuvant therapy; however, it is still unclear whether surgical sample expression profiles are useful for prediction via biopsy samples, because little has been done about comparative gene expression profiling between the two kinds of samples. METHODOLOGY AND FINDINGS: A total of 166 samples (77 biopsy and 89 surgical of normal and malignant lesions of the esophagus were analyzed by microarrays. Gene expression profiles were compared between biopsy and surgical samples. Artificially induced epithelial-mesenchymal transition (aiEMT was found in the surgical samples, and also occurred in mouse esophageal epithelial cell layers under an ischemic condition. Identification of clinically significant subgroups was thought to be disrupted by the disorder of the expression profile through this aiEMT. CONCLUSION AND SIGNIFICANCE: This study will evoke the fundamental misinterpretation including underestimation of the prognostic evaluation power of markers by overestimation of EMT IN past cancer research, and will furnish some advice for the near future as follows: 1 Understanding how long the tissues were under an ischemic condition. 2 Prevalence of biopsy samples for in vivo expression profiling with low biases on basic and clinical research. 3 Checking cancer cell contents and normal- or necrotic-tissue contamination in biopsy samples for prevalence.

  9. Evaluation of socio-economic effects of R and D results at Japan Atomic Energy Research Institute. 2. Socio-economic evaluation of the basic research at JAERI

    International Nuclear Information System (INIS)

    The Japan Atomic Energy Research Institute (JAERI), as a core organization devoted to comprehensive nuclear energy research, has steadily promoted various types of research and development (R and D) studies since its establishment in June 1956. Research activities are aimed at performing (1) R and D for nuclear energy, (2) the utilization and application of radiation-based technologies, and (3) the establishment of basic and fundamental research in the nuclear field. Last year, the socio-economic effects on items (1) and (2) were qualitatively and quantitatively evaluated. The quantitative evaluation of item (3) from the viewpoint of a socio-economic effect, however, calls for a different concept and methodology than previously used cost-benefit approach. Achievements obtained from the activities conducted over the last 10 years implied that socio-economics in basic research funded by the public could contribute to the (1) increase in useful intellectual stocks, (2) upbringing of highly skilled college graduates, (3) construction of new scientific facilities and creation of methodologies, (4) stimulation and promotion of social interrelations by networking, (5) increase of one's ability to solve scientific problems, and (6) establishment of venture companies. In this study, we focused on item (4) for the analysis because it assumed that the external economic effect has a link with the socio-economic effects accompanying the networking formation. For the criteria of socio-economic effects we assume that the external effect becomes significant in proportion to the width of networking and/or the magnitude of cooperation measured by numbers of co-writing studies between JAERI and the research bodies, namely private and governmental sectors and universities. Taking these criteria into consideration, the subsequent four items are prepared for quantitative study. They are (1) to clarify the basic research fields where JAERI has been established a significant effort to

  10. [NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 2:] Technical communications in aeronautics: Results of an exploratory study. An analysis of managers' and nonmanagers' responses

    Science.gov (United States)

    Pinelli, Thomas E.; Glassman, Myron; Barclay, Rebecca O.; Oliu, Walter E.

    1989-01-01

    Data collected from an exploratory study concerned with the technical communications practices of aerospace engineers and scientists were analyzed to test the primary assumption that aerospace managers and nonmanagers have different technical communications practices. Five assumptions were established for the analysis. Aerospace managers and nonmanagers were found to have different technical communications practices for three of the five assumptions tested. Although aerospace managers and nonmanagers were found to have different technical communications practices, the evidence was neither conclusive nor compelling that the presumption of difference in practices could be attributed to the duties performed by aerospace managers and nonmanagers.

  11. [NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 3:] Technical communications in aeronautics: Results of an exploratory study. An analysis of profit managers' and nonprofit managers' responses

    Science.gov (United States)

    Pinelli, Thomas E.; Glassman, Myron; Barclay, Rebecca O.; Oliu, Walter E.

    1989-01-01

    Data collected from an exploratory study concerned with the technical communications practices of aerospace engineers and scientists were analyzed to test the primary assumption that profit and nonprofit managers in the aerospace community have different technical communications practices. Five assumptions were established for the analysis. Profit and nonprofit managers in the aerospace community were found to have different technical communications practices for one of the five assumptions tested. It was, therefore, concluded that profit and nonprofit managers in the aerospace community do not have different technical communications practices.

  12. Bayesian Exploratory Factor Analysis

    DEFF Research Database (Denmark)

    Conti, Gabriella; Frühwirth-Schnatter, Sylvia; Heckman, James J.;

    2014-01-01

    This paper develops and applies a Bayesian approach to Exploratory Factor Analysis that improves on ad hoc classical approaches. Our framework relies on dedicated factor models and simultaneously determines the number of factors, the allocation of each measurement to a unique factor, and the corr......This paper develops and applies a Bayesian approach to Exploratory Factor Analysis that improves on ad hoc classical approaches. Our framework relies on dedicated factor models and simultaneously determines the number of factors, the allocation of each measurement to a unique factor......, and the corresponding factor loadings. Classical identification criteria are applied and integrated into our Bayesian procedure to generate models that are stable and clearly interpretable. A Monte Carlo study confirms the validity of the approach. The method is used to produce interpretable low dimensional aggregates...

  13. Research report of fiscal 1997. Basic research on the commercialization of innovative energy technologies; 1997 nendo chosa hokokusho. Kakushinteki energy gijutsu no jitsuyoka ni kansuru kiso chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper summarizes the research result in fiscal 1997 from the basic research results on the commercialization of innovative energy technologies. The target of a photovoltaic power generation market includes isolated power sources (several kWp) for distant places or developing countries, and those (several tens kWp) for personal residences or public facilities. Although the former is mainly promoted in the West, while the latter over the world, their profitability is unsolved. Power plants over several hundreds kWp are in demonstration test. Solar heat power generation of several tens to hundreds MWp is most profitable, however, small-scale one is poor in feasibility. Australia takes an interest in distributed photovoltaic power generation directly connected with actual lives of residents, and has a dominant opinion that desert is useless as large-scale site. This country lays emphasis on protection and maintenance rather than positive use of desert based on a basic cognition that desert is easily changed and broken. The Australian government announced power company`s obligation to use renewable energy by 2%, and a strong organization is scheduled to be newly established. 59 figs., 57 tabs.

  14. Discovery and Reuse of Open Datasets: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Sara

    2016-07-01

    Full Text Available Objective: This article analyzes twenty cited or downloaded datasets and the repositories that house them, in order to produce insights that can be used by academic libraries to encourage discovery and reuse of research data in institutional repositories. Methods: Using Thomson Reuters’ Data Citation Index and repository download statistics, we identified twenty cited/downloaded datasets. We documented the characteristics of the cited/downloaded datasets and their corresponding repositories in a self-designed rubric. The rubric includes six major categories: basic information; funding agency and journal information; linking and sharing; factors to encourage reuse; repository characteristics; and data description. Results: Our small-scale study suggests that cited/downloaded datasets generally comply with basic recommendations for facilitating reuse: data are documented well; formatted for use with a variety of software; and shared in established, open access repositories. Three significant factors also appear to contribute to dataset discovery: publishing in discipline-specific repositories; indexing in more than one location on the web; and using persistent identifiers. The cited/downloaded datasets in our analysis came from a few specific disciplines, and tended to be funded by agencies with data publication mandates. Conclusions: The results of this exploratory research provide insights that can inform academic librarians as they work to encourage discovery and reuse of institutional datasets. Our analysis also suggests areas in which academic librarians can target open data advocacy in their communities in order to begin to build open data success stories that will fuel future advocacy efforts.

  15. Basic Research Needs for Electrical Energy Storage. Report of the Basic Energy Sciences Workshop on Electrical Energy Storage, April 2-4, 2007

    Energy Technology Data Exchange (ETDEWEB)

    Goodenough, J. B.; Abruna, H. D.; Buchanan, M. V.

    2007-04-04

    To identify research areas in geosciences, such as behavior of multiphase fluid-solid systems on a variety of scales, chemical migration processes in geologic media, characterization of geologic systems, and modeling and simulation of geologic systems, needed for improved energy systems.

  16. Research on the Basic Issue of Criminology%对犯罪学基本问题的再思考

    Institute of Scientific and Technical Information of China (English)

    向准

    2015-01-01

    As the pre-subject of Criminal Law, Criminology is based on the social needs to prevent and reduce crime.Its research point is the crime phenomenon, then uses it to analyze the crime causes and finds the effective crime prevention measures.Thus, Crim-inology is composed of the definition, causes and prevention measures of crime.Only by thinking of these basic issues can we realize the theory of Criminology and do the in-depth research.%犯罪学作为刑法学的前置学科,基于预防和减少犯罪的社会需要应运而生。其以犯罪现象的现实存在为研究基点,以剖析复杂多样的犯罪原因和寻求行之有效的防控对策为支撑共筑犯罪学的整体。因而,何为犯罪、为什么犯罪与怎样预防成为犯罪学理论的基本问题。只有对这几个基本问题加以思考和分析才能对犯罪学有所理解,从而进行更为深入的犯罪学研究。

  17. Collection of summaries of reports on result of research at basic experiment device for nuclear fusion reactor blanket design, 1995

    International Nuclear Information System (INIS)

    This report meeting was held on May 22, 1995 at University of Tokyo by about 40 participants. As the topics on the fusion reactor engineering research in Japan, lectures were given on the present state and future of nuclear fusion networks and on the strong magnetic field tokamak using electromagnetic force-balanced coils being planned. Thereafter, the reports of the results of the researches which were carried out by using this experimental facility were made, centering around the subject related to the future conception 'The interface properties of fusion reactor materials and particle transport control'. The publication was made on the future conception of the basic experiment setup for fusion reactor blanket design, the application of high temperature superconductors to the advancement of nuclear fusion reactors, the modeling of the dynamic irradiation behavior of fusion reactor materials, the interface particle behavior in plasma-wall interaction, the behavior of tritium on the surface of breeding materials, and breeding materials and the behavior of tritium in plasma-wall interaction. (K.I.)

  18. Research investigations in oil shale, tar sand, coal research, advanced exploratory process technology, and advanced fuels research: Volume 2 -- Jointly sponsored research program. Final report, October 1986--September 1993

    Energy Technology Data Exchange (ETDEWEB)

    Smith, V.E.

    1994-09-01

    Numerous studies have been conducted in five principal areas: oil shale, tar sand, underground coal gasification, advanced process technology, and advanced fuels research. In subsequent years, underground coal gasification was broadened to be coal research, under which several research activities were conducted that related to coal processing. The most significant change occurred in 1989 when the agreement was redefined as a Base Program and a Jointly Sponsored Research Program (JSRP). Investigations were conducted under the Base Program to determine the physical and chemical properties of materials suitable for conversion to liquid and gaseous fuels, to test and evaluate processes and innovative concepts for such conversions, to monitor and determine environmental impacts related to development of commercial-sized operations, and to evaluate methods for mitigation of potential environmental impacts. This report is divided into two volumes: Volume 1 consists of 28 summaries that describe the principal research efforts conducted under the Base Program in five topic areas. Volume 2 describes tasks performed within the JSRP. Research conducted under this agreement has resulted in technology transfer of a variety of energy-related research information. A listing of related publications and presentations is given at the end of each research topic summary. More specific and detailed information is provided in the topical reports referenced in the related publications listings.

  19. Basic Research Needs for Solid-State Lighting. Report of the Basic Energy Sciences Workshop on Solid-State Lighting, May 22-24, 2006

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, J. M.; Burrows, P. E.; Davis, R. F.; Simmons, J. A.; Malliaras, G. G.; So, F.; Misewich, J.A.; Nurmikko, A. V.; Smith, D. L.; Tsao, J. Y.; Kung, H.; Crawford, M. H.; Coltrin, M. E.; Fitzsimmons, T. J.; Kini, A.; Ashton, C.; Herndon, B.; Kitts, S.; Shapard, L.; Brittenham, P. W.; Vittitow, M. P.

    2006-05-24

    The workshop participants enthusiastically concluded that the time is ripe for new fundamental science to beget a revolution in lighting technology. SSL sources based on organic and inorganic materials have reached a level of efficiency where it is possible to envision their use for general illumination. The research areas articulated in this report are targeted to enable disruptive advances in SSL performance and realization of this dream. Broad penetration of SSL technology into the mass lighting market, accompanied by vast savings in energy usage, requires nothing less. These new ?good ideas? will be represented not by light bulbs, but by an entirely new lighting technology for the 21st century and a bright, energy-efficient future indeed.

  20. Exploratory practice: A new perspective for college English teachers' research%探索型实践:高校英语教师研究新视角

    Institute of Scientific and Technical Information of China (English)

    郑志恋

    2009-01-01

    英国著名语言学家Dick Allwright在行动研究的基础上提出了以理解语言课堂生活质量为宗旨的"探索型实践"(Exploratory Practice),其国内外影响正在逐步扩大.本文首先阐述它的内涵,然后从技术、知识和道德三个纬度分析它的演变过程,最后列举了三个教学事例,从不同侧面说明高校英语教师在日常教学中如何开展探索型实践活动.

  1. Brain Basics

    Medline Plus

    Full Text Available ... as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the brain ... specialized for the function of conducting messages. A neuron has three basic parts: Cell body which includes ...

  2. Asthma Basics

    Science.gov (United States)

    ... Tropical Delight: Melon Smoothie Pregnant? Your Baby's Growth Asthma Basics KidsHealth > For Parents > Asthma Basics Print A ... Asthma Categories en español Asma: aspectos fundamentales About Asthma Asthma is a common lung condition in kids ...

  3. Brain Basics

    Medline Plus

    Full Text Available ... Basics will introduce you to some of this science, such as: How the brain develops How genes and the environment affect the brain The basic structure of the brain How different parts of ...

  4. Backpack Basics

    Science.gov (United States)

    ... How Can I Help a Friend Who Cuts? Backpack Basics KidsHealth > For Teens > Backpack Basics Print A ... it can cause back problems or even injury. Backpacks Are Best Backpacks can't be beat for ...

  5. Measurement of Separated Flow Structures Using a Multiple-Camera DPIV System. [conducted in the Langley Subsonic Basic Research Tunnel

    Science.gov (United States)

    Humphreys, William M., Jr.; Bartram, Scott M.

    2001-01-01

    A novel multiple-camera system for the recording of digital particle image velocimetry (DPIV) images acquired in a two-dimensional separating/reattaching flow is described. The measurements were performed in the NASA Langley Subsonic Basic Research Tunnel as part of an overall series of experiments involving the simultaneous acquisition of dynamic surface pressures and off-body velocities. The DPIV system utilized two frequency-doubled Nd:YAG lasers to generate two coplanar, orthogonally polarized light sheets directed upstream along the horizontal centerline of the test model. A recording system containing two pairs of matched high resolution, 8-bit cameras was used to separate and capture images of illuminated tracer particles embedded in the flow field. Background image subtraction was used to reduce undesirable flare light emanating from the surface of the model, and custom pixel alignment algorithms were employed to provide accurate registration among the various cameras. Spatial cross correlation analysis with median filter validation was used to determine the instantaneous velocity structure in the separating/reattaching flow region illuminated by the laser light sheets. In operation the DPIV system exhibited a good ability to resolve large-scale separated flow structures with acceptable accuracy over the extended field of view of the cameras. The recording system design provided enhanced performance versus traditional DPIV systems by allowing a variety of standard and non-standard cameras to be easily incorporated into the system.

  6. What can we do about exploratory analyses in clinical trials?

    Science.gov (United States)

    Moyé, Lem

    2015-11-01

    The research community has alternatively embraced then repudiated exploratory analyses since the inception of clinical trials in the middle of the twentieth century. After a series of important but ultimately unreproducible findings, these non-prospectively declared evaluations were relegated to hypothesis generating. Since the majority of evaluations conducted in clinical trials with their rich data sets are exploratory, the absence of their persuasive power adds to the inefficiency of clinical trial analyses in an atmosphere of fiscal frugality. However, the principle argument against exploratory analyses is not based in statistical theory, but pragmatism and observation. The absence of any theoretical treatment of exploratory analyses postpones the day when their statistical weaknesses might be repaired. Here, we introduce examination of the characteristics of exploratory analyses from a probabilistic and statistical framework. Setting the obvious logistical concerns aside (i.e., the absence of planning produces poor precision), exploratory analyses do not appear to suffer from estimation theory weaknesses. The problem appears to be a difficulty in what is actually reported as the p-value. The use of Bayes Theorem provides p-values that are more in line with confirmatory analyses. This development may inaugurate a body of work that would lead to the readmission of exploratory analyses to a position of persuasive power in clinical trials. PMID:26390962

  7. What can we do about exploratory analyses in clinical trials?

    Science.gov (United States)

    Moyé, Lem

    2015-11-01

    The research community has alternatively embraced then repudiated exploratory analyses since the inception of clinical trials in the middle of the twentieth century. After a series of important but ultimately unreproducible findings, these non-prospectively declared evaluations were relegated to hypothesis generating. Since the majority of evaluations conducted in clinical trials with their rich data sets are exploratory, the absence of their persuasive power adds to the inefficiency of clinical trial analyses in an atmosphere of fiscal frugality. However, the principle argument against exploratory analyses is not based in statistical theory, but pragmatism and observation. The absence of any theoretical treatment of exploratory analyses postpones the day when their statistical weaknesses might be repaired. Here, we introduce examination of the characteristics of exploratory analyses from a probabilistic and statistical framework. Setting the obvious logistical concerns aside (i.e., the absence of planning produces poor precision), exploratory analyses do not appear to suffer from estimation theory weaknesses. The problem appears to be a difficulty in what is actually reported as the p-value. The use of Bayes Theorem provides p-values that are more in line with confirmatory analyses. This development may inaugurate a body of work that would lead to the readmission of exploratory analyses to a position of persuasive power in clinical trials.

  8. Predicting Stress Related to Basic Needs and Safety in Darfur Refugee Camps: A Structural and Social Ecological Analysis

    OpenAIRE

    Rasmussen, Andrew; Annan, Jeannie

    2009-01-01

    The research on the determinants of mental health among refugees has been largely limited to traumatic events, but recent work has indicated that the daily hassles of living in refugee camps also play a large role. Using hierarchical linear modelling to account for refugees nested within camp blocks, this exploratory study attempted to model stress surrounding safety and acquiring basic needs and functional impairment among refugees from Darfur living in Chad, using individual-level demograph...

  9. Proceedings of the Scientific Meeting and Presentation on Basic Research in Nuclear Science and Technology part I: Physics, Nuclear Reactor and Instrumentation

    International Nuclear Information System (INIS)

    Scientific Meeting and Presentation on Basic Research in Nuclear Scienceand Technology is an annual activity held by Centre for Research and Development of Advanced Technology, National Nuclear Energy Agency, for monitoring research activities achieved by the Agency. The papers presented in the meeting were collected into proceedings which were divided into two parts. These are the first part of the proceedings that contain 42 articles in the fields of physics, nuclear reactors, and instrumentation (PPIN).

  10. Mobile Technologies Adoption: An Exploratory Case Study

    Institute of Scientific and Technical Information of China (English)

    CHU Yan; HUANG Lihua

    2008-01-01

    Based on the theory of task-technology fit and literature review of mobile technology acceptance, a research model is presented based on the features of mobile technologies and the actual usage of mobile applications in business environments, which identifies the characteristics of mobile applications and fitting tasks. An exploratory case is studied to understand how ABC Company, Hong Kong, utilizes mobile selling applications in their sales management process. This study gives some managerial suggestions for enterprises to successfully use mobile applications.

  11. Young Children's Haptic Exploratory Procedures

    Science.gov (United States)

    Kalagher, Hilary; Jones, Susan S.

    2011-01-01

    Adults vary their haptic exploratory behavior reliably with variation both in the sensory input and in the task goals. Little is known about the development of these connections between perceptual goals and exploratory behaviors. A total of 36 children ages 3, 4, and 5 years and 20 adults completed a haptic intramodal match-to-sample task.…

  12. 农田基本建设投资研究%Research on Basic Farmland Construction Investment

    Institute of Scientific and Technical Information of China (English)

    佟贺

    2012-01-01

    农田基本建设投资政策问题,不仅是推动当前农田基本建设的需要,而且也是建立长期稳定的农田基本建设机制的需要.%The basic farmland construction investment policy is not only the need to promote the basic construction of the farmland, but also the need to establish stable long-term basic farmland construction mechanism.

  13. Use of portable blood physiology point-of-care devices for basic and applied research on vertebrates: a review

    Science.gov (United States)

    Stoot, Lauren J.; Cairns, Nicholas A.; Cull, Felicia; Taylor, Jessica J.; Jeffrey, Jennifer D.; Morin, Félix; Mandelman, John W.; Clark, Timothy D.; Cooke, Steven J.

    2014-01-01

    Non-human vertebrate blood is commonly collected and assayed for a variety of applications, including veterinary diagnostics and physiological research. Small, often non-lethal samples enable the assessment and monitoring of the physiological state and health of the individual. Traditionally, studies that rely on blood physiology have focused on captive animals or, in studies conducted in remote settings, have required the preservation and transport of samples for later analysis. In either situation, large, laboratory-bound equipment and traditional assays and analytical protocols are required. The use of point-of-care (POC) devices to measure various secondary blood physiological parameters, such as metabolites, blood gases and ions, has become increasingly popular recently, due to immediate results and their portability, which allows the freedom to study organisms in the wild. Here, we review the current uses of POC devices and their applicability to basic and applied studies on a variety of non-domesticated species. We located 79 individual studies that focused on non-domesticated vertebrates, including validation and application of POC tools. Studies focused on a wide spectrum of taxa, including mammals, birds and herptiles, although the majority of studies focused on fish, and typical variables measured included blood glucose, lactate and pH. We found that calibrations for species-specific blood physiology values are necessary, because ranges can vary within and among taxa and are sometimes outside the measurable range of the devices. In addition, although POC devices are portable and robust, most require durable cases, they are seldom waterproof/water-resistant, and factors such as humidity and temperature can affect the performance of the device. Overall, most studies concluded that POC devices are suitable alternatives to traditional laboratory devices and eliminate the need for transport of samples; however, there is a need for greater emphasis on rigorous

  14. Brain Basics

    Medline Plus

    Full Text Available ... Home Public Involvement Outreach Partners Alliance for Research Progress Coalition for Research Progress Legislative Activities Research Priorities Research Priorities Home Research ...

  15. 疼痛基础研究的困惑与挑战%The challenge of basic research in pain

    Institute of Scientific and Technical Information of China (English)

    曹君利

    2015-01-01

    Benefiting from the great achievements in Life Science, especially in the Neuroscience, Molecular Biology and Functional Brain Imaging, over the past 20 years, there has been substantial progress in revealing the genes, molecules, cells, and circuits that regulate physiologic and pathologic pain and in understanding neurobiological mechanisms of pain modulation.However, few of these advances have been translated into effective clinical therapeutic means or/and new and improved analgesics.Why, what factors resulted in the giant gap between the pain basic research and clinical diagnosis and treatment This paper reviews the history in pain theory development and the mechanisms of pain signal processing, and makes brief comments on the obstacles and challenges of translational research on pain.%自闸门控制学说提出以来,特别是近20年来,随着生命科学领域特别是神经科学、分子生物学以及脑功能成像的理论和技术研究的巨大进步,越来越多的参与生理性和病理性疼痛调控的基因、分子/信号通路和脑区/神经环路被发现,人们对疼痛调控机制的认识和探讨达到了前所未有的高度.但是,疼痛理论研究成果鲜有转化为有效的临床疼痛治疗方法和/或新的镇痛药物,是哪些因素导致了疼痛基础研究与临床诊疗之间的巨大鸿沟?就疼痛理论的发展历史和疼痛信号的处理过程予以梳理,对疼痛转化医学研究所处的困境进行分析.

  16. Basic tensions of governance of religious diversity: item-list for the socio-legal research (WP7)

    OpenAIRE

    Bader, V.

    2010-01-01

    The focus on basic tensions or conflicts between basic rights may be easily misunderstood. Tensions or conflicts between rights are, indeed, normative tensions but not of the kind of „normativity‟ characteristic for moral philosophy. Quite to the contrary, these are tensions inherent in empirical norms (i.e. norms claiming legal validity) both in International Covenants of Civil and Political Rights or the ECHR as well as in (Constitutional) Law of Member States, whether we call these constit...

  17. The internal basic research and radical innovation in firm%企业的内部基础研究与突破性创新

    Institute of Scientific and Technical Information of China (English)

    眭纪刚; 连燕华; 曲婉

    2013-01-01

    突破性创新是后发企业跨越式发展的重要途径,基础研究能为企业突破性创新积累相应的创新能力.但是我国企业的基础研究普遍不足,导致企业的突破性创新能力薄弱.鼓励企业重视基础研究,必须突破基础研究只能在公立科研机构进行的思想束缚,通过改革科技计划和项目管理制度,建设企业国家重点实验室等方式,充分发挥财政税收政策的导向作用,引导和支持企业加强基础研究.%Radical innovation is very important for firm to leap development, and basic research can accumulate innovation capacity for firm' s radical innovation. But the basic research in Chinese firms is insufficient, which lead to the poor radical innovation capacity of firm. To encourage firm paying more attention to basic research, it should change the old idea that basic research can only do in public research organization, reform the management mechanism of S&T program, build national key lab in firm, and play the roles of finance and tax policy, to support firm strength basic research.

  18. Basic electrotechnology

    CERN Document Server

    Ashen, R A

    2013-01-01

    BASIC Electrotechnology discusses the applications of Beginner's All-purpose Symbolic Instruction Code (BASIC) in engineering, particularly in solving electrotechnology-related problems. The book is comprised of six chapters that cover several topics relevant to BASIC and electrotechnology. Chapter 1 provides an introduction to BASIC, and Chapter 2 talks about the use of complex numbers in a.c. circuit analysis. Chapter 3 covers linear circuit analysis with d.c. and sinusoidal a.c. supplies. The book also discusses the elementary magnetic circuit theory. The theory and performance of two windi

  19. An exploratory study of services marketing in global markets: major areas of inquiry for the health care services industry.

    Science.gov (United States)

    Young, S; Erdem, S A

    1996-01-01

    It has been stated that one of the major challenges for the international marketer is the design of an efficient strategy for marketing services to international markets. This paper reviews some of the issues associated with services marketing in global markets along with the basic variables of service industries. An exploratory assessment of the health care services industry results in a list composed of several inquiry areas which should be examined by multinational companies. It is hoped that the review of the issues raised in this paper provides a basis for decision making and further research. PMID:10163027

  20. Proceeding of the Scientific Meeting and Presentation on Basic Research of Nuclear Science and Technology: Book II. Nuclear Chemistry, Process Technology, and Radioactive Waste Processing and Environment

    International Nuclear Information System (INIS)

    The proceeding contains papers presented on Scientific Meeting and Presentation on on Basic Research of Nuclear Science and Technology, held in Yogyakarta, 25-27 April 1995. This proceeding is second part of two books published for the meeting contains papers on nuclear chemistry, process technology, and radioactive waste management and environment. There are 62 papers indexed individually. (ID)

  1. Un Modelo Basico de Instruccion Directa Para la Ensenanza de la Metodologia de la Investigacion (Using the Basic Direct Model of Instruction To Teach an Introductory Research Model).

    Science.gov (United States)

    Serafin, Ana Gil

    This study examined the application of the Basic Direct Instruction Model (BDIM), a methodology designed to maximize student interest in instrumental and methodological courses, to graduate level educational leadership students. The research used qualitative techniques and a participatory approach with a sample of 92 beginning level Masters…

  2. Proceeding of the Scientific Meeting and Presentation on Basic Research of Nuclear Science and Technology: Book I. Physics, Reactor Physics and Nuclear Instrumentation

    International Nuclear Information System (INIS)

    The proceeding contains papers presented on Scientific Meeting and Presentation on on Basic Research of Nuclear Science and Technology, held in Yogyakarta, 25-27 April 1995. This proceeding is part one from two books published for the meeting contains papers on Physics, Reactor Physics and Nuclear Instrumentation as results of research activities in National Atomic Energy Agency. There are 39 papers indexed individually. (ID)

  3. Science Translational Medicine – improving human health care worldwide by providing an interdisciplinary forum for idea exchange between basic scientists and clinical research practitioners

    OpenAIRE

    Forsythe, Katherine

    2010-01-01

    Science Translational Medicine’s mission is to improve human health care worldwide by providing a forum for communication and interdisciplinary idea exchange between basic scientists and clinical research practitioners from all relevant established and emerging disciplines. The weekly journal debuted in October 2009 and is published by the American Association for the Advancement of Science (AAAS), the publisher of Science and Science Signaling. The journal features peer-reviewed research art...

  4. The Progress in Clinical and Basic Research of the Effect ofAcupuncture in Treating Disorders of Gastrointestinal Motility

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Though the function of “spleen” in TCM refers to a lot of systems, it is mainly related to digestive system, reflecting changes of physiology and pathology of gastrointestinal tract. The deficiency of Spleen Qi is correlated to the disorders of gastrointestinal motility.(19) In recent years the research has been developed in adjustment of Spleen and Stomach function and the improvement of gastrointestinal motility by acupuncturing mainly Zusanli, which formed a theoretic base for acupuncture therapy of disorders of gastrointestinal motility.Effect of Acupuncture on Gastric Peristalsis  Observation by gastroendoscopy and B-ultrasonography showed that, acupuncture at Zusanli could decrease gastric tension and resolve spasm of cardia, gastric body and pylorus, and improve delayed opening of pylorus, so as to make gastric hyperperistalsis tend to go placid and normalize retarding. It is demonstrated that acupuncture at Zusanli could adjust the function of gastric peristalsis bi-directionally.(20,21) In healthy volunteers after acupuncture at Zusanli the frequency and the amplititude of gastric peristalsis both increased. In patients whose pylorus ring could not open during the operation of gastroscopy, acupuncture at Zusanli could relax and open it. Acupuncture at Neiguan could produce either opening or closing the bi-directional effect of pylorus.(22) In patients with disorders of gastrointestinal motility it was observed that the amplititude and frequency of constriction of sphincter pylori increased and the strength and frequency of stomach improved after acupuncture at Zusanli according to the measurement of gastroscopic manometry.(23) Acupuncture may accelerate or reduce the speed of gastric evacuation.(24,25) In addition, acupuncture can increase the volume of gastric antrum. Observed by B-ultrasonography, acupuncture Zusanli, Shangjuxu (ST37), Chongyang (ST42) and Neiting (ST44) in the lower extremity section of the Yangming meridian of the foot could

  5. 城市品牌关系资产构成因素的探索性研究%Exploratory Research on the Components of City Brand Relationship Equity

    Institute of Scientific and Technical Information of China (English)

    唐玉生

    2011-01-01

    The core issues of regional economic development are urban development and their establishments of competitive advantages, the competitions among cities have entered a new phase of brand competition. To explore the issue of building city brand from angle of city brand relationship is still in the exploratory stage. A new concept named city brand relationship equity is proposed in this paper, an exploratory research for the components of city brand relationship equity is made by using factor analysis methods and structural equation model, the dimensions and their measurement items of city brand relationship equity are obtained. The 4 dimensions include city unite, city promises, city faith and city familiarity.%城市的发展及其竞争优势的建立是区域经济建设的核心问题,城市竞争已开始进入品牌竞争的新阶段.从城市品牌关系的视角探讨城市品牌的建设问题目前还处于探索阶段.采用探索性与验证性因子分析方法对城市品牌关系资产的构成因素进行探索性研究,得出了构成城市品牌关系资产的维度及其测项,即城市品牌关系资产由城市联合、城市承诺、城市信任、城市熟悉四个因子构成.

  6. Brain Basics

    Medline Plus

    Full Text Available ... pituitary-adrenal (HPA) axis. Brain Basics in Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah ... having trouble coping with the stresses in her life. She began to think of suicide because she ...

  7. Brain Basics

    Medline Plus

    Full Text Available ... Basics in Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle-aged woman who seemed to have it all. She was happily married and successful in business. Then, after a serious setback at work, she lost interest ...

  8. Inflation Basics

    Energy Technology Data Exchange (ETDEWEB)

    Green, Dan [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2014-03-01

    The last few years have yielded remarkable discoveries in physics. In particle physics it appears that a fundamental scalar field exists. The Higgs boson is measured to have a mass of about 126 GeV and to have spin zero and positive parity. The Higgs field is the first fundamental scalar to be discovered in physics. The Cosmic Microwave Background, CMB, is known to have a uniform temperature to parts per 105 but has well measured fluctuations which are thought to evolve gravitationally to provide the seeds of the current structure of the Universe. In addition, the Universe appears to contain, at present, an unknown “dark energy” which is presently the majority energy density of the Universe, larger than either matter or radiation. This may, indeed, be a fundamental scalar field like the Higgs. “Big Bang” (BB) cosmology is a very successful “standard model” in cosmology. However, it cannot explain the uniformity of the CMB because the CMB consists of many regions not causally connected in the context of the BB model. In addition, the Universe appears to be spatially flat. However in BB cosmology the present spatial curvature is not stable so that the initial conditions for BB cosmology would need to be fantastically fine-tuned in order to successfully predict the presently small value of the observed curvature. These issues for BB cosmology have led to the hypothesis of “inflation” which postulates an unknown scalar field, not presumably the Higgs field or the dark energy, which causes an exponential expansion of the Universe at very early times. This attractive hypothesis can account for the problems in BB cosmology of flatness and causal CMB connectivity. In addition, the quantum fluctuations of this postulated field provide a natural explanation of the CMB fluctuations which are the seeds of the structure of galaxies. Researchers are now searching for gravitational waves imprinted on the CMB. These would be a “smoking gun” for

  9. 我国幼儿基本体操研究的综述%Review of Research on Children's Basic Gymnastics in China

    Institute of Scientific and Technical Information of China (English)

    谢开华

    2015-01-01

    Children's basic gymnastics to promote children's physical growth and development of children, improve body function, enhance the body's coordination, sensitivity etc. In this paper, using the method of literature, logical analysis, development and research status of children's basic gymnastics is discussed. Think the research actuality of China children's basic gymnastics, gymnastics power need development and inconsistent, puts forward the research of infant basic gymnastics empirical in the cross disciplinary theoretical knowledge guidance, to provide reference for improving children's constitution, and Gymnastics Reserve Talents and provide a theoretical basis.%幼儿基本体操能够促进幼儿身体生长发育,提高幼儿身体机能,增强身体的协调性、灵敏性等。采用文献资料法、逻辑分析法,论述幼儿基本体操的发展及科研现状。认为我国幼儿基本体操的科研现状,与体操强国发展需要不符,提出应在交叉学科理论知识的指导下进行幼儿基本体操实证研究,为改善幼儿体质提供参考,并为体操后备人才储备提供理论依据。

  10. Theatrical fire pursuant exploratory laparotomy

    OpenAIRE

    Bellevue, Oliver C.; Johnson, Bennett M.; Feczko, Andrew F.; Nadig, Daniel E.; White, David M.

    2016-01-01

    Fire in the operating theater is a rare but potentially fatal complication. We report igniting an intraperitoneal fire while preforming an exploratory laparotomy for perforated viscus. Fortunately, the patient suffered no injuries as a result.

  11. Basic hydraulics

    CERN Document Server

    Smith, P D

    1982-01-01

    BASIC Hydraulics aims to help students both to become proficient in the BASIC programming language by actually using the language in an important field of engineering and to use computing as a means of mastering the subject of hydraulics. The book begins with a summary of the technique of computing in BASIC together with comments and listing of the main commands and statements. Subsequent chapters introduce the fundamental concepts and appropriate governing equations. Topics covered include principles of fluid mechanics; flow in pipes, pipe networks and open channels; hydraulic machinery;

  12. Research on the Countermeasures Based on TTPM Theory for the Improvement of the Basic Education Teachers Training Performance

    Science.gov (United States)

    Huabai, Bu; Dengyu, Zhang; Xiuying, Shen; Hao, Tu

    2012-01-01

    Many elements of the basic education teachers' training performance are embedded in the training interaction and sharing, so the enhancement of the training performance needs a whole process management and control. Based on TTPM theory, this paper has put forward four measures that must be pay attention to during the management of the basic…

  13. Basic Need Satisfaction and Identity Formation: Bridging Self-Determination Theory and Process-Oriented Identity Research

    Science.gov (United States)

    Luyckx, Koen; Vansteenkiste, Maarten; Goossens, Luc; Duriez, Bart

    2009-01-01

    The fulfillment of the basic psychological needs for autonomy, competence, and relatedness as postulated within self-determination theory was hypothesized to play an energizing role in identity formation, conceptualized as multiple dimensions of exploration and commitment. Two studies among high school and college students (N = 714) were conducted…

  14. Exploratory data analysis with Matlab

    CERN Document Server

    Martinez, Wendy L; Solka, Jeffrey

    2010-01-01

    Since the publication of the bestselling first edition, many advances have been made in exploratory data analysis (EDA). Covering innovative approaches for dimensionality reduction, clustering, and visualization, Exploratory Data Analysis with MATLAB®, Second Edition uses numerous examples and applications to show how the methods are used in practice.New to the Second EditionDiscussions of nonnegative matrix factorization, linear discriminant analysis, curvilinear component analysis, independent component analysis, and smoothing splinesAn expanded set of methods for estimating the intrinsic di

  15. Brain Basics

    Medline Plus

    Full Text Available ... the anatomy, physiology, and chemistry of the nervous system. When the brain cannot effectively coordinate the billions ... basic working unit of the brain and nervous system. These cells are highly specialized for the function ...

  16. Brain Basics

    Medline Plus

    Full Text Available ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics will introduce you to some of this science, such as: How the brain develops How ... cell, and responds to signals from the environment; this all helps the cell maintain its balance with ...

  18. Brain Basics

    Medline Plus

    Full Text Available ... How the brain develops How genes and the environment affect the brain The basic structure of the ... inside contents of the cell from its surrounding environment and controls what enters and leaves the cell, ...

  19. Brain Basics

    Science.gov (United States)

    ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  20. Cancer Basics

    Science.gov (United States)

    ... Cancer? Breast Cancer Colon/Rectum Cancer Lung Cancer Prostate Cancer Skin Cancer Show All Cancer Types News and Features Cancer Glossary ACS Bookstore Cancer Information Cancer Basics Cancer Prevention & Detection Signs & Symptoms of Cancer Treatments & Side Effects ...

  1. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... learning more about how the brain grows and works in healthy people, and how normal brain development ...

  2. Basic Finance

    Science.gov (United States)

    Vittek, J. F.

    1972-01-01

    A discussion of the basic measures of corporate financial strength, and the sources of the information is reported. Considered are: balance sheet, income statement, funds and cash flow, and financial ratios.

  3. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... others live with symptoms of mental illness every day. They can be moderate, or serious and cause ...

  4. Brain Basics

    Medline Plus

    Full Text Available ... the function of conducting messages. A neuron has three basic parts: Cell body which includes the nucleus, ... Plan in 2016 August 31, 2016, 2:00-3:00 PM ET Recovery Month September 2016 National ...

  5. Blood Basics

    Science.gov (United States)

    ... Patient Group Links Advocacy Toolkit Home For Patients Blood Basics Blood is a specialized body fluid. It ... about 9 pints. Jump To: The Components of Blood and Their Importance Many people have undergone blood ...

  6. Brain Basics

    Medline Plus

    Full Text Available ... for the function of conducting messages. A neuron has three basic parts: Cell body which includes the ... disorder (ADHD) . Glutamate —the most common neurotransmitter, glutamate has many roles throughout the brain and nervous system. ...

  7. Brain Basics

    Medline Plus

    Full Text Available ... interconnections. neuron —A nerve cell that is the basic, working unit of the brain and nervous system, which processes and transmits information. neurotransmitter —A chemical produced by ...

  8. Brain Basics

    Medline Plus

    Full Text Available ... The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the ... distant nerve cells (via axons) to form brain circuits. These circuits control specific body functions such as ...

  9. Brain Basics

    Medline Plus

    Full Text Available ... science, such as: How the brain develops How genes and the environment affect the brain The basic ... that with brain development in people mental disorders. Genes and environmental cues both help to direct this ...

  10. Body Basics

    Science.gov (United States)

    ... about how the body works, what basic human anatomy is, and what happens when parts of the body don't function properly. Blood Bones, Muscles, and Joints Brain and Nervous System Digestive System Endocrine System Eyes Female Reproductive System ...

  11. Brain Basics

    Medline Plus

    Full Text Available ... Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a ... blues" from time to time. In contrast, major depression is a serious disorder that lasts for weeks. ...

  12. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 15: Technical uncertainty and project complexity as correlates of information use by US industry-affiliated aerospace engineers and scientists: Results of an exploratory investigation

    Science.gov (United States)

    Pinelli, Thomas E.; Glassman, Nanci A.; Affelder, Linda O.; Hecht, Laura M.; Kennedy, John M.; Barclay, Rebecca O.

    1993-01-01

    An exploratory study was conducted that investigated the influence of technical uncertainty and project complexity on information use by U.S. industry-affiliated aerospace engineers and scientists. The study utilized survey research in the form of a self-administered mail questionnaire. U.S. aerospace engineers and scientists on the Society of Automotive Engineers (SAE) mailing list served as the study population. The adjusted response rate was 67 percent. The survey instrument is appendix C to this report. Statistically significant relationships were found to exist between technical uncertainty, project complexity, and information use. Statistically significant relationships were found to exist between technical uncertainty, project complexity, and the use of federally funded aerospace R&D. The results of this investigation are relevant to researchers investigating information-seeking behavior of aerospace engineers. They are also relevant to R&D managers and policy planners concerned with transferring the results of federally funded aerospace R&D to the U.S. aerospace industry.

  13. Survey of basic data on human resources development (HRD) in the nuclear field in FNCA countries (Contract research)

    International Nuclear Information System (INIS)

    In the 3rd FNCA* (Forum for Nuclear Cooperation in Asia) Coordinator Meeting held on March 2002, it was proposed to carry out 'Survey of the Basic Data on Human Resources Development in the Nuclear Field'. It was considered to be the first step for developing the HRD strategy by producing the quantitative data on HRD in nuclear field. The survey results were introduced by Project Leaders during the 2002 FNCA Workshop on HRD held on October 2002. The follow-up survey was conducted with the cooperation of other Project Leaders in the respective field of FNCA such as medical and agriculture applications in each member countries. The collected survey data was analyzed in 2003, and summarized as 'Summary of the Survey Data'. This report consists of the summary of 'Survey of the Basic Data on Human Resources Development in Nuclear Field'. It was reported during the 2003 FNCA Workshop on HRD held on October 2003 and updated until early 2004. (author)

  14. Insomnia Treatments (Beyond the Basics)

    Science.gov (United States)

    ... education: Daytime sleepiness (The Basics) Patient education: Jet lag (The Basics) Patient education: What is a sleep ... use by UpToDate, but only for the clinical, educational or research purposes of the Institution. Further, access ...

  15. Research on confirmation of basic technological parameters of tension levellers based on neural network and genetic algorithm

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Confirmation of basic technological parameters of tension levellers is the most important factor of leveling strip. Up to now, most factories have used experts’ experience to decide these parameters, without any established rule to follow. For better quality of strip, a valid method is needed to decide technological parameters precisely and reasonably. In this paper, a method is used based on neural network and genetic algorithm. Neural network has a good ability to extract rules from work process of tensio...

  16. Deliberative Democracy and Precautionary Public Reasoning : Exploratory Thoughts

    OpenAIRE

    Genevieve Fuji-Johnson

    2006-01-01

    Because public policy is legally binding and, perhaps more pointedly, can have pervasive social and environmental consequences for the autonomy of persons, it should be justifiable to those it could so affect. What is much more controversial, and what constitutes the basic intuitive claim of this exploratory paper, is that certain public policies should be morally justifiable to both existing and future persons. My concern is with policies in such areas as energy, climate change control, nucl...

  17. Science Translational Medicine - improving human health care worldwide by providing an interdisciplinary forum for idea exchange between basic scientists and clinical research practitioners

    OpenAIRE

    Forsythe, K

    2010-01-01

    Science Translational Medicine 's mission is to improve human health care worldwide by providing a forum for communication and interdisciplinary idea exchange between basic scientists and clinical research practitioners from all relevant established and emerging disciplines. The weekly journal debuted in October 2009 and is published by the American Association for the Advancement of Science (AAAS), the publisher of Science and Science Signaling . The journal features peer-reviewed researc...

  18. Class Evolution Tree: A Graphical Tool to Support Decisions on the Number of Classes in Exploratory Categorical Latent Variable Modeling for Rehabilitation Research

    Science.gov (United States)

    Kriston, Levente; Melchior, Hanne; Hergert, Anika; Bergelt, Corinna; Watzke, Birgit; Schulz, Holger; von Wolff, Alessa

    2011-01-01

    The aim of our study was to develop a graphical tool that can be used in addition to standard statistical criteria to support decisions on the number of classes in explorative categorical latent variable modeling for rehabilitation research. Data from two rehabilitation research projects were used. In the first study, a latent profile analysis was…

  19. Basic electronics

    CERN Document Server

    Holbrook, Harold D

    1971-01-01

    Basic Electronics is an elementary text designed for basic instruction in electricity and electronics. It gives emphasis on electronic emission and the vacuum tube and shows transistor circuits in parallel with electron tube circuits. This book also demonstrates how the transistor merely replaces the tube, with proper change of circuit constants as required. Many problems are presented at the end of each chapter. This book is comprised of 17 chapters and opens with an overview of electron theory, followed by a discussion on resistance, inductance, and capacitance, along with their effects on t

  20. Deliberative Democracy and Precautionary Public Reasoning : Exploratory Thoughts

    Directory of Open Access Journals (Sweden)

    Genevieve Fuji-Johnson

    2006-05-01

    Full Text Available Because public policy is legally binding and, perhaps more pointedly, can have pervasive social and environmental consequences for the autonomy of persons, it should be justifiable to those it could so affect. What is much more controversial, and what constitutes the basic intuitive claim of this exploratory paper, is that certain public policies should be morally justifiable to both existing and future persons. My concern is with policies in such areas as energy, climate change control, nuclear waste management, natural resources management, and genomics research and commercialization, which can no doubt improve our lives and our descendant’s lives, but which can also result in tremendous adverse effects for centuries to come. In this short paper, I suggest that the ideal of deliberative democracy provides a way of morally justifying such policies to both existing and future generations. If we take seriously the requirements of this ideal, we may have to modify our public reasoning so that it includes reasons that are generally acceptable among contemporaries as well as reasons that would be acceptable to posterity. The suggestion I make in this paper is thatintegral to the ideal of deliberative democracy in the transgenerational contextis a future-oriented and precautionary public reasoning.

  1. Brain Basics

    Medline Plus

    Full Text Available ... Activities Research Priorities Research Priorities Home Research Areas Policies and Procedures Research Resources Research Domain Criteria (RDoC) ... of Medicine Contact Us Staff Directories Privacy Notice Policies FOIA Accessibility Topic Finder Publicaciones en Español The ...

  2. Formative research on the primo vascular system and acceptance by the korean scientific community: the gap between creative basic science and practical convergence technology.

    Science.gov (United States)

    Kim, Hoon Gi

    2013-12-01

    The purpose of this study was to trace the formative process of primo vascular system (PVS) research over the past decade and to describe the characteristics of the Korean scientific community. By publishing approximately 30 papers in journals ranking in the Science Citation Index (Expanded), the PVS research team actively convinced domestic and international scientists of the anatomical existence of the PVS and its possible application to Korean and Western medicine. In addition, by sharing the PVS observation technique, the team promoted the dissemination and further pursuit of the research. In 2012, however, PVS researchers performed smaller scale research without advancing to a higher level as compared to the early days. The main reasons were found to be the Korean Research and Development policy of supporting creative, small-scale basic research and applied research of Western scientific fields that promised potentially greater success on an extensive scale; the indifference concerning, and the disbelief in, the existence of a new circulatory system were shown by the Western medical community. In addition, the Oriental medical community was apathetic about working with the PVS team. Professors Kwang-Sup Soh and Byung-Cheon Lee were the prime movers of PVS research under difficult conditions. Spurred by their belief in the existence and significance of the PVS, they continued with their research despite insufficient experimental data. The Korean scientific community is not ready to promote the Korea-oriented creative field of the PVS team.

  3. 诺贝尔自然科学奖与基础研究%Nobel Natural Science Prize and Basic Research

    Institute of Scientific and Technical Information of China (English)

    陈其荣

    2013-01-01

    文章主要提出并探讨了三个具有内在关联的问题:一是基础研究的类型问题。基础研究是一个随着科学研究实践的发展而演进的范畴,通过对现代科学从“学院科学”向“后学院科学”转变的历史考析,得出基础研究的范畴已从只是“纯基础研究”的一种类型拓展为包括“纯基础研究”和“定向基础研究”两种类型的结论,结合诺贝尔自然科学奖获得者从事基础研究的实际案例,对这两种不同类型的基础研究范畴做出了新的阐释。二是诺贝尔自然科学奖获得者从事基础研究的比重究竟有多大。通过对诺贝尔自然科学奖获得者从事基础研究(分为“纯基础研究”与“定向基础研究”)与应用研究获奖工作的人数与比例的统计分析,发现高达90%左右的科学家是由于在基础科学领域取得重大原始性创新成果而被授予诺贝尔自然科学奖的,彰显了权威的诺贝尔自然科学奖对基础研究的“偏爱”,从而显示出基础研究的重要意义。三是诺贝尔自然科学奖获得者是如何从事基础研究的。依据真实、丰富而鲜活的思想资料,运用案例分析法,深入分析和揭示了他们作为科学精英在基础科学领域取得重大原始性创新成果的“奥秘”。%Three interrelated issues are explored in this paper.The first is about the category of basic re-search.The paper points out that the scope of basic research evolves with the progress of the practice of scien-tific research.Based on a close examination of the historical transformation of modern science from "academic science"to the "post-academic science",it argues that the scope of basic research has expanded.Besides "pure basic research",there appears the new category of"oriented basic research".These two categories are explained and interpreted in relation to the actual cases of basic research by Nobel Laureates for natural

  4. NETWORK CLASSIFICATION ON THE BASIS OF FUNCTIONS THEY PERFORM AND ITS RELATIONSHIP WITH INTERNATIONALIZATION PROCESS OF SMEs IN DEVELOPING COUNTRIES---exploratory research on Pakistan

    OpenAIRE

    Seerat Fatima; Prof. Dr. Mujahid Ali; Sheraz Arif

    2011-01-01

    The purpose of this study is to classify the networks according to functions they performed, especially scrutinize their structures. The research concentrates on the influence of these functional networks on the internationalization process of small and medium sized companies (SME) in developing countries. What are the different types of support being provided by network partners? What is the structure of the existing network? The research part is inductive, qualitative and based on case stud...

  5. Use of the Pyrithiamine-Induced Thiamine Deficient Animal Model of Korsakoff’s Syndrome for Exploratory Research Activities in Undergraduate Physiological Psychology

    OpenAIRE

    Flint, Robert W.; Hill, Jonathan E.; Sandusky, Leslie A.; Marino, Christina L.

    2007-01-01

    Undergraduate neuroscience laboratory activities frequently focus on exercises that build student’s wet/dry laboratory skills, foster critical thinking, and provide opportunities for hands-on experiences. Such activities are, without a doubt, extremely important, but sometimes fall short of modeling actual research and often lack the ‘unknown’ hypothetical nature accompanying empirical studies. In this article we report a series of research activities using an animal model of Korsakoff’s synd...

  6. 基础研究与图书馆学的学科地位%Basic Research and the Disciplinary Status of Library Science

    Institute of Scientific and Technical Information of China (English)

    张新兴; 郑永田; 杨志刚

    2012-01-01

    The promotion of disciplinary status of library science relies on the construction of mature theoretical system and the advance of discipline impact factors, in the final analysis it depends on the improvement of basic research capacity. Rational configuration of library science research resources, attracting diverse main bodies of research, following scientific and normative research procedure are the required elements to improve the library science basic research capacity.%图书馆学学科地位的提高依靠成熟完备的理论体系的构建和学科影响因子的提升,归根结底要以基础研究水平的提高来实现。合理配置图书馆学研究资源,吸纳多元化的研究主体,遵循科学规范的研究程序等是提高图书馆学基础研究水平的必备要素。

  7. 云计算环境下可视化探索式搜索引擎的研究%The Research on Visual Exploratory Search Engine in Cloud Computing Environment

    Institute of Scientific and Technical Information of China (English)

    周莉; 王珏; 周勇

    2015-01-01

    针对目前搜索引擎返回的信息量过大且缺乏语义关联等问题,提出了一种云计算环境下的可视化探索式搜索引擎模型。该模型通过对元搜索引擎返回的原始信息在云计算环境下语义相似度的计算和语义链的构建,采用探索式搜索方法为用户获取个性化的结果。与传统搜索引擎相比,其结果更加直观地表现了目标信息及其之间丰富的语义关系,该方法使用户能够更为自然而有效地在海量的信息中发现更符合其需求的目标。作为实验模型,还需要更多的元搜索引擎的支持,以及进一步计算优化语义相似度的算法,才能使该模型真正实用化。本研究为云计算环境下构建新一代个性化智能搜索引擎提供了理论和实践上的参考。%A visual exploratory search engine model based on cloud computing has been proposed for the enormous numbers information and lack of Semantics relationship of the traditional search engine. The model obtains personal-ized result for users using exploratory search method ,via semantic similarity computation and semantic link con-struction on the raw information returned from meta-search engine. Compared with the traditional search engine,the results are more intuitive on the represent of the target information and their rich semantic relations. Users can more naturally and efficiently found their target in line with their needs in the massive amount of information. As an ex-perimental model,in order to make this model practical,it needs more meta-search engine's support,and further op-timization of semantic similarity computation algorithm. The research of the model provides theoretical and practical reference for the construction of new generation of personalized intelligent search engine on the cloud computing en-vironment.

  8. Basic Backwardness.

    Science.gov (United States)

    Weingartner, Charles

    This paper argues that the "back to basics" movement is regressive and that regression is the characteristic mode of fear-ridden personalities. It is argued that many people in American society today have lost their ability to laugh and do not have the sense of humor which is crucial to a healthy mental state. Such topics as necrophilia, mental…

  9. Brain Basics

    Medline Plus

    Full Text Available ... Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle-aged woman ... new memories. hypothalmic-pituitary-adrenal (HPA) axis —A brain-body ... stress. impulse —An electrical communication signal sent between neurons ...

  10. Brain Basics

    Medline Plus

    Full Text Available ... Welcome. Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... highly developed area at the front of the brain that, in humans, plays a role in executive functions such as ...

  11. Ethanol Basics

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-01-30

    Ethanol is a widely-used, domestically-produced renewable fuel made from corn and other plant materials. More than 96% of gasoline sold in the United States contains ethanol. Learn more about this alternative fuel in the Ethanol Basics Fact Sheet, produced by the U.S. Department of Energy's Clean Cities program.

  12. Basic Skills.

    Science.gov (United States)

    Luparelli, Augustus N.; And Others

    1981-01-01

    These four articles focus on developing basic reading, science, and job search skills: "Reading Program for Vocational Classes" by Augustus Luparelli; "Why Teach Employability Skills?" by Larry Siefferman; "Improving Vocabulary and Reading Skills" by Edythe Conway; and "Science in Everyday Life" by Virginia Eleazer and George Carney. (SK)

  13. Report on the actual state of the basic, applied research and industrial applications of the radiation in Mexico; Informe sobre el estado actual de la investigacion basica, aplicada y aplicaciones industriales de la radiacion en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Lopez V, H

    1991-07-15

    In this report the main works of basic, applied research and industrial applications that are carried out in Mexico, about radiations (radiation chemistry, technology, applications, use and isotope production, etc.): infrastructure, radiation sources, groups and research programs are presented. (Author)

  14. Swiss energy research program on energy economics basics for 2008-2011; Energieforschungsprogramm. Energiewirtschaftliche Grundlagen (EWG) fuer die Jahre 2008-2011

    Energy Technology Data Exchange (ETDEWEB)

    Mathys, N. A.

    2009-07-01

    This report published by the Swiss Federal Office of Energy (SFOE) introduces the energy research programme on energy economics basics for the years 2008 - 2011. The programme is very interdisciplinary and uses many theoretical and empirical methods from the areas of micro and macro-economy, political science and socio-psychology. The budget available for research in this area is discussed and the various institutions involved are noted. Both public and private funding is discussed. The main areas of research being targeted for the period 2008 - 2011 in the areas of energy policy and applied research are discussed. These include improvements in the methods used for energy perspectives and innovation as well as social and individual factors influencing the use of energy.

  15. [Substance use disorders as a cause and consequence of childhood abuse. Basic research, therapy and prevention in the BMBF-funded CANSAS-Network].

    Science.gov (United States)

    Schäfer, Ingo; Barnow, Sven; Pawils, Silke

    2016-01-01

    Substance use disorders (SUDs) belong to the most frequent behavioural consequences of childhood abuse and neglect (CAN). In community samples, about 20% of adults with experiences of abuse or neglect in childhood have a lifetime diagnosis of an SUD. About 30% of individuals seeking treatment for a post-traumatic disorder have an SUD and 24–67% of all patients in treatment for an SUD have a history of CAN. About 16% of all children and adolescents under the age of 20 in Germany grow up in families where an alcohol- and/or drug-dependence is present. The children of parents with SUDs have, in addition to other risks to their development in cognitive and psychosocial domains, an increased risk of experiencing violence and neglect. Regarding both perspectives, SUD as a cause and as a consequence of CAN, a better understanding of relevant mediators and risk factors is necessary to improve prevention and develop adequate treatments. The aims of the BMBF-funded research network CANSAS are: 1. To gain a better understanding of the relationships between these two important public health problems (basic research), 2. To provide evidence-based treatments for survivors of CAN with SUDs and to increase the awareness for the necessity to diagnose CAN in patients with SUDs in counselling and treatment facilities (research on diagnostics and therapy), 3. To improve the systematic evaluation of child welfare among children of parents with SUDs through counselling services and to promote links between addiction services and youth welfare services (prevention research and health services research). In a multidisciplinary approach, the CANSAS network brings together experts in the fields of trauma treatment, epidemiology, basic research, health services research, prevention research as well as addiction services. PMID:26497814

  16. Quantum electronics basic theory

    CERN Document Server

    Fain, V M; Sanders, J H

    1969-01-01

    Quantum Electronics, Volume 1: Basic Theory is a condensed and generalized description of the many research and rapid progress done on the subject. It is translated from the Russian language. The volume describes the basic theory of quantum electronics, and shows how the concepts and equations followed in quantum electronics arise from the basic principles of theoretical physics. The book then briefly discusses the interaction of an electromagnetic field with matter. The text also covers the quantum theory of relaxation process when a quantum system approaches an equilibrium state, and explai

  17. Inhibitions and implications associated with celebrity participation in health-related social marketing: an exploratory research focused on HIV prevention in Portugal.

    Science.gov (United States)

    Casais, Beatriz; Proença, João F

    2012-01-01

    This article discusses motivations and inhibitions among celebrities to participate in health-related social marketing. The research identifies the implications that this involvement may have upon their lives. Results from in-depth interviews with 27 Portuguese celebrities show that they expect a fee for endorsements of commercial and government social marketing, despite the positive image they may gain from endorsing public health. The results demonstrate an absence of celebrity prejudice against HIV because of its serious nature and the social stigma attached to AIDS. This research suggests there is a positive bias and presents helpful information for negotiations between institutions and celebrities. PMID:22905943

  18. Basic research needs in seven energy-related technologies, conservation, conversion, transmission and storage, environmental fission, fossil, geothermal, and solar

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    This volume comprises seven studies performed by seven groups at seven national laboratories. The laboratories were selected because of their assigned lead roles in research pertaining to the respective technologies. Researches were requested to solicit views of other workers in the fields.

  19. Doctoral Education in a Successful Ecological Niche: A Qualitative Exploratory Case Study of the Relationship between the Microclimate and Doctoral Students' Learning to Become a Researcher

    Science.gov (United States)

    Christensen, Mette K.; Lund, Ole

    2014-01-01

    Scholarly communities are dependent on and often measured by their ability to attract and develop doctoral students. Recent literature suggests that most scholarly communities entail ecological niches in which the doctoral students learn the codes and practices of research. In this article, we explore the microclimate in an ecological niche of…

  20. An Exploratory Analysis of the Relationship between Student Earnings and Postsecondary Retention. University of Kentucky Center for Poverty Research Discussion Paper Series, DP2010-13

    Science.gov (United States)

    Jepsen, Christopher; Patel, Darshak; Troske, Kenneth

    2010-01-01

    Policymakers are becoming increasingly concerned about the high percentage of students who attend postsecondary education without completing a degree. Researchers have studied numerous potential determinants of retention behavior for postsecondary students, such as financial aid, socioeconomic status, academic preparedness, academic and social…

  1. Exploratory data analysis with Matlab

    CERN Document Server

    Martinez, Wendy L; Solka, Jeffrey

    2004-01-01

    Exploratory data analysis (EDA) was conceived at a time when computers were not widely used, and thus computational ability was rather limited. As computational sophistication has increased, EDA has become an even more powerful process for visualizing and summarizing data before making model assumptions to generate hypotheses, encompassing larger and more complex data sets. There are many resources for those interested in the theory of EDA, but this is the first book to use MATLAB to illustrate the computational aspects of this discipline.Exploratory Data Analysis with MATLAB presents the meth

  2. Research on confirmation of basic technological parameters of tension levellers based on neural network and genetic algorithm

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Confirmation of basic technological parameters of tension levellers is the most important factor of leveling strip. Up to now, most factories have used experts' experience to decide these parameters, without any established rule to follow. For better quality of strip, a valid method is needed to decide technological parameters precisely and reasonably. In this paper, a method is used based on neural network and genetic algorithm. Neural network has a good ability to extract rules from work process of tension levellers. Then using neural network, which has learned from a lot of working samples, to be the evaluation of fitness, genetic algorithm could easily find the best or better technological parameters. At the end of this paper, examinations are given to show the effect of this method.

  3. The three avenues of gerontology: from basic research to clinical gerontology and anti-aging medicine. Another French paradox.

    Science.gov (United States)

    Robert, Leslie

    2004-06-01

    This is a contribution to the debate raised by the position statement on aging ( 1) and comments ( 2) concerning the rapid increase of anti-aging medicine. After a short summary of the history of social attitude to aging and the emergence of experimental gerontology, the French situation is described, emphasizing the economic basis of this phenomenon: increasing insurance fees and tightly controlled honoraria push an increasing number of physicians to this new discipline. No lack of communication seems to be involved between basic gerontologists and physicians ( 2). Anti-aging medicine profits of the increasing population of seniors who want to remain healthy, look young and dislike to consult geriatricians. And also of the fact that no over-the-counter delivery of drugs is available in France. For these reasons there is no serious hope to stop it otherwise than by state legislation. PMID:15215259

  4. 基础和应用基础研究是创新药物研究与开发的源泉%The basic and applied basic researches are the foundation of research and development of new drugs

    Institute of Scientific and Technical Information of China (English)

    杨秀伟; 张礼和

    2001-01-01

    From the soon-to-be-completed Human Genome Project to Combinatorial Chemistry and High-Throughput Screening combined with bioinformatic tools, scie n tific advances are poised to revolutionize drug discovery and even health care. The research directions in the State Key Laboratory of Natural and Biomimetic Dr ugs of Peking University mainly focus on the study of interaction between biolog ical targets and active compounds with structural diversity including endogeno us and exogenous substances, especially the natural products that come from anim als, plants and inorganic medicines. The new lead compounds have been designed and s ynthesized based on the structure-activity relationship and computer modeling. T he research activities are involved in 76 national research projects. From 1996 -20 00, 310 papers have been published, 8 patents obtained an d 14 prizes of scientific achievements awarded by the Chinese government and min istries.

  5. 关于外语教学中的文化撞击现象探究%Exploratory Research of the Cultural Impact Based on Language Learning

    Institute of Scientific and Technical Information of China (English)

    蒋燕

    2011-01-01

    语言学习者普遍感到:在具备一定的基础语言知识和语言能力后,对语言学习的突破仍有瓶颈,那就是文化撞击。揭示文化学习的意义,在语言学习中融入文化教学的重要性日益突出。文章旨在探讨语言学习中文化撞击、误会发生的原因,通过剖析本国文化和目标文化的差异,提出相关策略,加强对文化的理解,提高跨文化的交际能力,使外语教学取得实效。%Language learners are commonly felt that having the availability of certain basic linguistic knowledge and language skills, the breakthrough in the language learning is still a bottleneck, it is culture shock. It's so important to reveal the significance of cultural learning and to penetrate culture education in teaching consciously. This article aims to explore the reason of cultural impact, misunderstanding in language learning through analysis of differences between our own culture and target culture and put forward relevant strategies to enhance cultural understanding, enhance cross--cultural communication skills, and make foreign language teaching to be effective.

  6. Adult Response to Children's Exploratory Behaviours: An Exploratory Study

    Science.gov (United States)

    Chak, Amy

    2010-01-01

    Children's interest in exploration is the hallmark of their curiosity. As people who are significant in organising children's environment, how teachers and parents respond to children's exploratory behaviours may promote or hinder the child's desire for further investigation. With reference to Kurt Lewin's concept of "total situation", various…

  7. Applying the Theory of Work Adjustment to Latino Immigrant Workers: An Exploratory Study

    Science.gov (United States)

    Eggerth, Donald E.; Flynn, Michael A.

    2015-01-01

    Blustein mapped career decision making onto Maslow’s model of motivation and personality and concluded that most models of career development assume opportunities and decision-making latitude that do not exist for many individuals from low income or otherwise disadvantaged backgrounds. Consequently, Blustein argued that these models may be of limited utility for such individuals. Blustein challenged researchers to reevaluate current career development approaches, particularly those assuming a static world of work, from a perspective allowing for changing circumstances and recognizing career choice can be limited by access to opportunities, personal obligations, and social barriers. This article represents an exploratory effort to determine if the theory of work adjustment (TWA) might meaningfully be used to describe the work experiences of Latino immigrant workers, a group living with severe constraints and having very limited employment opportunities. It is argued that there is significant conceptual convergence between Maslow’s hierarchy of needs and the work reinforcers of TWA. The results of an exploratory, qualitative study with a sample of 10 Latino immigrants are also presented. These immigrants participated in key informant interviews concerning their work experiences both in the United States and in their home countries. The findings support Blustein’s contention that such workers will be most focused on basic survival needs and suggest that TWA reinforcers are descriptive of important aspects of how Latino immigrant workers conceptualize their jobs. PMID:26345693

  8. NETWORK CLASSIFICATION ON THE BASIS OF FUNCTIONS THEY PERFORM AND ITS RELATIONSHIP WITH INTERNATIONALIZATION PROCESS OF SMEs IN DEVELOPING COUNTRIES---exploratory research on Pakistan

    Directory of Open Access Journals (Sweden)

    Seerat Fatima

    2011-10-01

    Full Text Available The purpose of this study is to classify the networks according to functions they performed, especially scrutinize their structures. The research concentrates on the influence of these functional networks on the internationalization process of small and medium sized companies (SME in developing countries. What are the different types of support being provided by network partners? What is the structure of the existing network? The research part is inductive, qualitative and based on case study. The study’s findings illustrate the subtleties of how various network partners interact with entrepreneurs to penetrate, integrate and extend their international markets. Networks can help entrepreneurs expose themselves to new opportunities, obtain knowledge, learn from experiences, and benefit from the synergistic effect of pooled resources. Another contribution of this paper is that it identifies structures of the functional networks, till date networks are classified on the basis of extent of support they provide, not on what support they provide, thus advancing the literature.

  9. Commentary: a practical guide for translating basic research on affective science to implementing physiology in clinical child and adolescent assessments.

    Science.gov (United States)

    Aldao, Amelia; De Los Reyes, Andres

    2015-01-01

    The National Institute of Mental Health recently launched the Research Domain Criteria (RDoC). RDoC is a framework that facilitates the dimensional assessment and classification of processes relevant to mental health (e.g., affect, regulation, cognition, social affiliation), as reflected in measurements across multiple units of analysis (e.g., physiology, circuitry, genes, self-reports). A key focus of RDoC involves opening new lines of research examining patients' responses on biological measures, with the key goal of developing new therapeutic techniques that effectively target mechanisms of mental disorders. Yet applied researchers and practitioners rarely use biological measures within mental health assessments, which may present challenges in translating RDoC-guided research into improvements in patient care. Thus, if RDoC is to result in research that yields clinical tools that reduce the burden of mental illness and improve public health, we ought to develop strategies for effectively implementing biological measures in the context of clinical assessments. In this special issue, we sought to provide an initial step in this direction by assembling a collection of articles from leading research teams carrying out pioneering work on implementing multimodal assessments (biological, subjective, behavioral) of affective processes in applied settings. In this commentary, we expand upon the work presented in this special issue by making a series of suggestions for how to most parsimoniously conduct multimodal assessments of affective processes in applied research and clinical settings. We hope that this approach will facilitate translations of the RDoC framework into applied research and clinic settings.

  10. 50 CFR 300.106 - Exploratory fisheries.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  11. User-Driven Innovation: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Blanka Tacer

    2015-03-01

    Full Text Available Despite the relatively robust promotion of user-driven innovation (UDI in practice, research on UDI remains in its early stages. Following a grounded theory analysis approach, this paper makes a contribution by conducting exploratory research of the field. Nine interviews yield an empirical basis for extracting categories connected with existing conceptual issues. The results reveal three key elements of the UDI (user involvement, searching for feedback, and design orientation. The results also indicate the interdisciplinary nature of UDI with branding, design, and company-user interaction as complementary fields in creating user experience. The analysis leads to four theoretical propositions for future studies. The article concludes with limitations and implications for future research.

  12. Improvement of basic food crops in Africa through plant breeding, including the use of induced mutations. Proceedings of a final research co-ordination meeting

    International Nuclear Information System (INIS)

    The Co-ordinated Research Programme (CRP) on Improvement of Basic Food Crops in Africa Through Plant Breeding, Including the Use of Induced Mutations, funded by the Italian Government, was initiated in 1989 in the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. The primary objective of this CRP was to breed improved varieties of stable food crops of Africa with the main emphasis on the indigenous species and their local cultivars. The fourth and final Research Co-ordination meeting under the CRP was held in Naples, Italy from 30 October - 3 November 1995. This publication includes the reports, conclusions and recommendations made by the participants. We hope that it will be of value to researchers, students and policy makers alike in their endeavour to promote plant breeding and increase food productions in Africa. Refs, figs, tabs

  13. Insulin Basics

    Science.gov (United States)

    ... for Association Events Messaging Tools Recruiting Advocates Local Market Planning Training Webinars News & Events Advocacy News Call to Congress The Cost of Diabetes Research & Practice Home We Are Research Leaders World's Largest ...

  14. Brain Basics

    Medline Plus

    Full Text Available ... Research: Harnessing Science to Strengthen the Public Health Impact Bethesda, MD, August 1-3, 2016 Webinar: Mental ... NIH Research Fact Sheets NIH Office of Science Education : Resources for science educators Pillbox: How to identify ...

  15. Brain Basics

    Medline Plus

    Full Text Available ... Spanish ( Español ) ClinicalTrials.gov : Federally and privately supported research using human volunteers PubMed Central: An archive of life sciences journals NIH Research Fact Sheets NIH Office of Science Education : Resources ...

  16. [NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 1, part 2:] Technical communications in aeronautics: Results of an exploratory study

    Science.gov (United States)

    Pinelli, Thomas E.; Glassman, Myron; Oliu, Walter E.; Barclay, Rebecca O.

    1989-01-01

    A study was undertaken that explored several aspects of technical communications in aeronautics. The study, which utilized survey research in the form of a self-administered questionnaire, was sent to 2,000 randomly selected members of the American Institute of Aeronautics and Astronautics. Six hundred and six usable questionnaires (30.3 percent) were received by the established cut off date. Part 2 of this study lists appendices to part 1, including survey instrument, aggregate totals, cross tabulations, and open-ended comments.

  17. Exploratory research on course teaching of architectural design based on ability cultivation of practice and innovation - Take course teaching of high-rise building design as an example

    Directory of Open Access Journals (Sweden)

    Gao Ming

    2016-01-01

    Full Text Available Under current disciplinary development reform and the objective of strengthening ability cultivation of practice innovation, this thesis makes comprehensive analysis of the problems existing in “high-rise building design” teaching for undergraduates majoring in architecture; and proposes new philosophies of focusing on teaching process, opening up joint school management and research-oriented teaching in combination of construction transformation demands. Based on the above background, this thesis also proposes the teaching conception of establishing multi-platform frame. Moreover, it discusses corresponding platform establishment and teaching design in combination of educational reform practice.

  18. Academic plagiarism prevalence among Spanish undergraduate students: an exploratory analysis

    OpenAIRE

    Comas-Forgas, Rubén; Sureda-Negre, Jaume; Salva-Mut, Francesca

    2010-01-01

    Introduction: The present research article is an exploratory study on academic plagiarism practices among Spanish university students. Materials and methods: To answer the main research questions, we based our work on a cross-sectional survey of the targeted population. The sample consisted of a total of 560 students and the procedure was non-probability sampling. Results and conclusions: The research findings show that the Internet has become the students’ main source for the plagiaris...

  19. Basic research on the carbon dioxide fixation using seaweed. Kaisorui no tansan gas kotei ni kansuru kiso kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, M.; Ishihara, T. (The Kansai Electric Power Co. Inc., Osaka (Japan))

    1993-08-25

    Study was made for grasping the basic data of CO2 fixation technology by seaweed. The photosynthesis under the sea, which is different from that on the land, is judged to be made by taking in HCO3[sup -] and converting it into CO2 inside the plant. Porphyra yezoensis which is seaweed is cultivated as comestible. With a rise in CO2 content, the growth in length of leaves was observed to be accelerated through ventilating Porphyra yezoensis with the three test types of air which respectively contained 350ppm (atmospheric CO2 content), 1000ppm and 1600ppm CO2. As a result of measuring the photosynthesis speed by the generated quantity of O2, it was heightened with a rise in dissolved inorganic carbonic acid content of the sea water. Measurement was also made of daily fluctuation in calcification speed by Corallina officinalis capable of calcification by ventilating it with 350ppm and 1600ppm CO2. In case of 1600ppm, the sedimentation of CaCO3 was prevented. In case of 350ppm, the sedimentation was quantitatively larger during the bright period than that during the dark period. The growth of Gracilaria gigas which is an agar material was compared by changing the above CO2 levels. In case of 1600ppm, the weight grew to 2.3 times in 20 days. 16 figs., 2 tabs.

  20. An economic and financial exploratory

    NARCIS (Netherlands)

    S. Cincotti; D. Sornette; P. Treleaven; S. Battiston; G. Caldarelli; C.H. Hommes; A. Kirman

    2012-01-01

    This paper describes the vision of a European Exploratory for economics and finance using an interdisciplinary consortium of economists, natural scientists, computer scientists and engineers, who will combine their expertise to address the enormous challenges of the 21st century. This Academic Publi