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Sample records for basf-industriekernkraftwerk reaktor 1

  1. ANALISIS KECELAKAAN REAKTOR AKIBAT KEGAGALAN SISTEM PEMBUANG PANAS PADA REAKTOR NUKLIR GENERASI IV

    Directory of Open Access Journals (Sweden)

    A. G. Abdullah

    2012-05-01

    Full Text Available Salah satu aspek terpenting dalam proses desain reaktor nuklir adalah aspek keselamatan reaktor. Sebelum membangun reaktor secara fisik, terlebih dahulu dibuat perencaaan perhitungan yang matang termasuk melakukan simulasi kinerja keselamatannya dalam menghadapi kemungkinan kecelakaan. Penelitian ini bertujuan untuk mengembangkan model simulasi kecelakaan Pembangkit Listrik Tenaga Nuklir (PLTN yang disebabkan  gagalnya sistem pembuang panas. Kecelakaan akibat gagalnya sistem pembuang panas dipicu oleh hilangnya kemampuan pendinginan dari pembangkit uap. Urutan kecelakaan ini diawali dengan hilangnya kemampuan reaktor untuk membuang panas dari loop pendingin sekunder. Selama kecelakaan, laju pembuangan panas mengalami penurunan sedangkan temperatur masukan pendingin mengalami peningkatan. Hasil simulasi memberikan gambaran bahwa reaktor dapat bertahan dari kecelakaan. Hasil analisis kecelakaan menunjukkan bahwa temperatur maksimum bahan bakar, selongsong dan pendingin memiliki batas keselamatan yang sangat besar.One of the most important aspects in nuclear reactor design process is the safety aspect. Advanced and accurate safety simulation must be performed before it can be built.  This research aims to develop a simulation model of Nuclear Power Plant (NPP accidents due to the loss of  heat sink system. Loss of heat sink accident was triggered by the loss of cooling capability of steam generators.  This  accident  sequence  began with the loss of the reactor’s ability to remove heat from the secondary cooling loop. During the accident, the heat dissipation rate decreased whereas the coolant inlet temperatures increased till a new equilibrium level. The analysis results of the accident showed that there are large safety margin to the maximum temperature of the fuel, cladding, and coolant.

  2. Fire modeling of the Heiss Dampf Reaktor containment

    International Nuclear Information System (INIS)

    This report summarizes Sandia National Laboratories' participation in the fire modeling activities for the German Heiss Dampf Reaktor (HDR) containment building, under the sponsorship of the United States Nuclear Regulatory Commission. The purpose of this report is twofold: (1) to summarize Sandia's participation in the HDR fire modeling efforts and (2) to summarize the results of the international fire modeling community involved in modeling the HDR fire tests. Additional comments, on the state of fire modeling and trends in the international fire modeling community are also included. It is noted that, although the trend internationally in fire modeling is toward the development of the more complex fire field models, each type of fire model has something to contribute to the understanding of fires in nuclear power plants

  3. Fire modeling of the Heiss Dampf Reaktor containment

    Energy Technology Data Exchange (ETDEWEB)

    Nicolette, V.F. [Sandia National Labs., Albuquerque, NM (United States); Yang, K.T. [Notre Dame Univ., IN (United States)

    1995-09-01

    This report summarizes Sandia National Laboratories` participation in the fire modeling activities for the German Heiss Dampf Reaktor (HDR) containment building, under the sponsorship of the United States Nuclear Regulatory Commission. The purpose of this report is twofold: (1) to summarize Sandia`s participation in the HDR fire modeling efforts and (2) to summarize the results of the international fire modeling community involved in modeling the HDR fire tests. Additional comments, on the state of fire modeling and trends in the international fire modeling community are also included. It is noted that, although the trend internationally in fire modeling is toward the development of the more complex fire field models, each type of fire model has something to contribute to the understanding of fires in nuclear power plants.

  4. PENGARUH GEMPA PATAHAN LEMBANG TERHADAP FLEKSIBILITAS PIPA DAN KEGAGALAN NOZEL PERALATAN SISTEM PENDINGIN PRIMER REAKTOR TRIGA 2000 BANDUNG

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    H.P. Raharjo

    2012-02-01

    Full Text Available Gempa bumi di suatu instalasi nuklir dapat menyebabkan terjadinya kerusakan sistem peralatan karena adanya perubahan fleksibilitas pipa akibat beban berlebih pada sistem perpipaannya. Beban dari sistem perpipaan dapat membebani nozel peralatan seperti pompa, penukar panas, dll. Apabila beban tersebut terlalu besar dan melebihi beban yang diizinkan akan mengakibatkan kegagalan nozel peralatan. Penelitian ini menganalisis besarnya beban-beban yang terjadi di semua nozel  sistem pendingin primer Reaktor TRIGA 2000 Bandung. Analisis dilakukan dengan bantuan perangkat lunak Caesar II yang berbasis metode elemen hingga (finite element method. Acuan analisis yang digunakan adalah code ASME B31.1 yang mengatur tentang perancangan sistem perpipaan untuk sistem pembangkit daya (Power Piping. Hasil analisis menunjukkan bahwa gaya yang terjadi pada nozel masukan pompa arah aksial (FZ melebihi batas yang diijinkan. Oleh karena itu perlu dilakukan modifikasi terhadap jalur perpipaan sistem pendingin tersebut agar nozel tidak menerima gaya yang berlebih. Penyangga pipa titik(node 22 di jalur PriOut dilepas dan/atau dipindahkan pada nozel masukkan pompa. Perpipaan sistem pendingin primer reaktor TRIGA 2000 Bandung akan aman beroperasi jika terjadi gempa.yang berasal dari patahan Lembang Kata kunci : gempa bumi, patahan, perpipaan, reaktor, sistem pendingin

  5. PENINGKATAN KINERJA SISTEM KESELAMATAN PASIF PADA REAKTOR NUKLIR DENGAN PENAMBAHAN KOMPONEN RVACS

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    A. G. Abdullah

    2014-07-01

    Full Text Available Kelengkapan sistem keselamatan pasif dan inheren pada reaktor lanjut merupakan prasyarat utama. Makalah ini mengeksplorasi hasil desain konseptual sistem pembuang sisa panas pada pusat listrik tenaga nuklir berjenis Very High-Temperature Reactor. Tujuan riset ini untuk merancang sistem pembuang sisa panas pusat listrik tenaga nuklir yang terdapat pada dinding reaktor. Studi kinerja Reactor Vessel Auxliary Cooling System (RVACS dilakukan pada dua jenis pendingin yaitu Timbal-Bismut dan Liquid Salt. Panas dari dinding reaktor dihapus melalui sirkulasi alamiah pada keadaan tunak. Analisis melibatkan sistem perpindahan panas secara radiasi, konduksi dan konveksi alami. Perhitungan perpindahan panas dilakukan pada elemen reaktor vessel, dinding luar guard vessel, dan pelat pemisah. Hasil analisis kecelakaan menunjukkan kedua jenis sistem pendingin reaktor dan sistem pasif sisa pembuangan panas cukup menghapus sisa panas hasil peluruhan dengan sirkulasi alami.ABSTRACTCompleteness of passive safety systems and inherent in advanced reactors is a major prerequisite. This paper explores the results of a conceptual design of the heat removal system at the nuclear power plant (NPP type Very High-Temperature Reactor. The purpose of this research was to design the reactor vessel auxiliary cooling system (RVACS of NPP located within the reactor walls. The RVACS performance study was conducted on two types of coolant: Lead-Bismuth and Liquid Salt. Heat was removed from the reactor vessel through the natural circulation in the steady state. Analyses of heat transfer systems involved radiation, conduction and natural convection. Heat transfer calculations were performed on the reactor vessel, guard vessel, and perforated plate. The results from the accident analysis showed that both types, the reactor coolant system and the passive residual heat removal system, adequately remove remaining heat of the decay by a natural circulation.

  6. Studi Pembuatan Pupuk Kalium Sulfat dari Abu Sekam Padi dan Gipsum Alam Menggunakan Reaktor Tangki Berpengaduk

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    Muhammad Husin Ismayanda

    2015-07-01

    Full Text Available Proses pembuatan pupuk kalium sulfat umumnya dibuat dari asam klorida dan bahan baku yang mengandung anion sulfat (SO4. Dalam penelitian ini, pembuatan pupuk kalium sulfat dari bahan baku batuan gipsum alam sebagai sumber sulfat dan abu sekam padi sebagai sumber kalium telah dilakukan. Penelitian ini bertujuan mengkaji kemungkinan pembuatan pupuk kalium sulfat dari gipsum alam dan abu sekam padi dan juga mengetahui pengaruh kecepatan pengadukan, temperatur operasi dan waktu proses terhadap persentase konversi kalium sulfat yang dihasilkan. Dalam penelitian ini juga dipelajari kinetika reaksi yang terjadi selama proses pembentukan kalium sulfat. Proses pembuatan pupuk kalium sulfat dilakukan dalam reaktor tangki berpengaduk. Varibel berubah dari penelitian ini adalah kecepatan putaran pengaduk, temperatur proses, dan waktu reaksi. Untuk menganalisis produk yang dihasilkan, metode yang digunakan mengacu pada Standar Nasional Indonesia (SNI 02-2809-2005. Hasil penelitian menunjukkan bahwa pupuk kalium sulfat dapat dihasilkan dari reaksi antara gipsum yang mengandung kalsium sulfat dan abu sekam padi yang mengandung kalium karbonat dengan konversi kalium dari endapan sebesar 99,87% dan konversi kalium dari filtrat sebanyak 18,22%. Nilai konversi sulfat dari endapan hanya sebesar 0,69% dan nilai konversi sulfat dari filtrat 0,26%.Dalam penelitian ini kondisi terbaikproses pembuatan pupuk kalium sulfat adalah pada waktu reaksi 80 menit, kecepatan putaran pengaduk 400 rpm dan temperatur operasi 90ºC. Hasil analisis juga menunjukkan bahwa produk pupuk kalium sulfat tidak mengandung asam bebas sebagai H2SO4 dan klorida (Cl, akan tetapi mengandung kalium dan sulfat. Nilai konstanta kecepatan reaksi (k yang didapat dalam penelitian ini adalah sebesar 0,00218 ppm-1 menit-1 dan nilai laju pengurangan reaktan (rA sebesar 8,129 x 10-5 ppm/menit.

  7. PERFORMA OKSIDASI METAN PADA REAKTOR KONTINYU DENGAN PENINGKATAN KETEBALAN LAPISAN BIOCOVER LANDFILL

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    Opy Kurniasari

    2013-11-01

    methane through the form of methanol metabolite. ABSTRAKPenanganan sampah kota di Indonesia pada umumnya dilakukan pada tempat pemrosesan akhir sampah (TPA, yang sebagian besar dilakukan dengan cara pengurugan (landfilling yang cenderung bersifat anaerob (tidak ada oksigen. Cara pengurugan ini biasanya dioperasikan lapis perlapis sehingga memungkinkan terjadinya proses anaerob. Pada kondisi ini dipastikan biogas, yaitu gas metana (CH4 dan CO2, akan muncul. Metana adalah gas rumah kaca dengan potensi pemanasan global lebih besar dari CO2, dan dapat mengabsorpsi radiasi infra merah 23 kali lebih efisien dari CO2 pada periode lebih dari 100 tahun. Salah satu cara yang dapat dilakukan untuk mengurangi gas metana dari landfill yang lepas ke alam adalah dengan mengoksidasinya dengan memanfaatkan material penutup landfill (biocover sebagai media mikroorganisma pengoksidasi metana. Aplikasi kompos sebagai material penutup landfill merupakan pendekatan dengan biaya rendah untuk mereduksi emisi gas dari landfill sehingga cocok untuk negara berkembang. Biocover yang digunakan pada penelitian ini adalah kompos landfill mining, yaitu kompos yang terdegradasi secara alami di landfill. Tujuan penelitian ini adalah mengevaluasi kemampuan biocover kompos landfill mining dalam mengoksidasi metana pada ketebalan lapisan tertentu dengan kondisi aliran kontinyu. Tiga buah reaktor kolom yang digunakan terbuat dari flexy glass berukuran tinggi 70 cm dan diameter 15 cm. Gas metana dialirkan dari bawah reaktor secara kontinyu dengan laju alir 5 ml/menit. Kolom diisi dengan biocover kompos landfill mining dengan ketebalan lapisan 5, 25, 35 dan 60 cm. Hasil percobaan menunjukkan bahwa semakin tebal lapisan biocover, semakin tinggi efisiensi oksidasi metana. Efisiensi oksidasi yang diperoleh pada setiap ketebalan lapisan 15, 25, 35 dan 60 cm adalah masing-masing 56,43%, 63,69%, 74,58% dan 80,03%, dengan laju oksidasi 0,287 mol m-2 d-1 dan fraksi oksidasi 97%. Hasil oksidasi yang diperoleh tersebut

  8. Theory of nuclear reactors. Vol. 1. Theorie der Kernreaktoren. Bd. 1. Der stationaere Reaktor

    Energy Technology Data Exchange (ETDEWEB)

    Emendoerfer, D.; Hoecker, K.H.

    1982-01-01

    An introduction is given to the elements of reactor physics and reactor calculation which refers to practice from the present point of view. It is demonstrated to the reader how the reactor characteristics relevant to construction can be calculated from atomic factors by means of neutron transport and diffusion theory; these reactor characteristics are: multiplication factor, power density distribution, burn-up, plutonium build-up, xenon vibrations, short-time behaviour. The interaction between thermo- and fluid-dynamic processes is important for this calculation. On grounds of didactics the crucial point of this book is the establishment and calculation of simple models which give a clear description of all important characteristics of the events. Attempts for more exact simulation by computer are dealt with including typical solutions.

  9. Návrh parního generátoru pro modulární reaktor

    OpenAIRE

    Černý, Marian

    2012-01-01

    Obsahem této diplomové práce je návrh parního generátoru pro modulární reaktor. Práce se skládá z rešeršní části, kde jsou popsané vybrané výměníky a parní generátory používané v jaderných zařízeních. Na rešerši navazuje část s teorií výpočtů v prvním přiblížení (tepelný, hydraulický a pevností výpočet). Následuje část návrhu konkrétních variant parního generátoru. Na autorem zvolenou variantu jsou provedeny výše uvedené výpočty a zhotovena výkresová dokumentace vybraných částí. Závěr této pr...

  10. Pembuatan Biodiesel Dari Minyak Kelapa Sawit RBD Dengan Menggunakan Katalis Berpromotor Ganda Berpenyangga γ-Alumina (CaO/MgO/ γ-Al2O3 Dalam Reaktor Fluidized Bed

    Directory of Open Access Journals (Sweden)

    Niar Kurnia Julianti

    2014-09-01

    Full Text Available Biodiesel merupakan salah satu energi alternatif pengganti bahan bakar fosil dari hasil reaksi transesterifikasi minyak nabati dengan metanol. Proses pembuatan biodiesel selama ini menggunakan katalis homogen NaOH atau KOH yang memiliki kelemahan terbentuknya produk samping berupa sabun dan rumitnya pemisahan produk biodiesel dengan katalis. Maka dari itu, mulai dikembangkan katalis heterogen. Penelitian ini mengembangkan katalis berpromotor ganda berpenyangga y-alumina (CaO/MgO/y-Al2O3 dalam reaktor fluidized bed. Pembuatan katalis melalui metode presipitasi CaO dan MgO pada y-Al2O3 serta asam asetat sebagai larutan precursor. Kemudian, katalis dioven selama 12 jam pada suhu 110C dan dikalsinasi pada suhu 700 C selama 5 jam. Katalis yang diperoleh digunakan untuk proses transesterifikasi dengan ratio molar minyak metanol 1:36; variabel massa katalis 4, 7, 10, 13, 16 gram; laju alir reaktan 4, 7, 10, 13, 16 ml/menit; dan suhu 125, 150, 175, 200, 225 C. Dimana yield dan % konversi terbaik dari penelitian diperoleh sebesar 0,642 gr biodiesel/gr minyak dan 63,975% pada massa katalis 16 gram, suhu 225 C dan laju alir reaktan 4 ml/menit.

  11. Reactor for biological elimination of poorly degradable hydrocarbons by adjustment of substrate-specific retention times; Reaktor zur biologischen Eliminierung schwer abbaubarer Kohlenwasserstoffe durch Einstellung substratspezifischer Verweilzeiten

    Energy Technology Data Exchange (ETDEWEB)

    Brambach, R.

    1997-11-01

    Industrial waste water cleaning increasingly makes use of biological processes based on immobilized biomass, in order to ensure the aimed elimination of toxic substances. A novel, efficient reactor technique was developed, by which dangerous, poorly degradable dissolved hydrocarbons are selectively retained in the bioreactor thanks to an integrated membrane, while other substances are quickly discharged from the system via the effluent. With a synthetic waste water, this selective retention method achieved substrate-specific retention times which were five to fifty times higher than those of a merely hydrodynamically operated reactor system. In addition, the decoupling of high reactor and low effluent concentrations results in a higher biochemical activity in the reactor in comparison with conventional process techniques. (orig.) [Deutsch] In der industriellen Abwasserreinigung werden verstaerkt Bioverfahrenstechniken mit immobilisierter Biomasse eingesetzt, um eine gezielte Eliminierung gefaehrlicher Stoffe durchzufuehren. - Hierzu wurde eine neuartige leistungsfaehige Reaktortechnik entwickelt, die mittels einer im Bioreaktor integrierten Membran gefaehrliche, schwer abbaubare geloeste Kohlenwasserstoffe selektiv im Bioreaktor zurueckhaelt, waehrend andere Stoffe das System schnell ueber den Ablauf verlassen. Durch den stoffselektiven Rueckhalt wurden an einem synthetischen Abwasser substratspezifische Verweilzeiten erzielt, die um den Faktor 5 bis 50 ueber denen eines rein hydrodynamisch bestimmten Reaktorsystems liegen. Darueber hinaus wird aufgrund der Entkopplung von hoher Reaktor- und niedriger Ablaufkonzentration eine im Vergleich zu herkoemmlichen Verfahrenstechniken hoehere biochemische Aktivitaet im Reaktor erzielt. (orig.)

  12. PENJERAPAN GAS CO HASIL PEMBAKARAN SAMPAH MENGGUNAKAN SORBENT TERMODIFIKASI DALAM REAKTOR FIXED BED

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    Mariana Mariana

    2013-11-01

    Full Text Available ADSORPTION OF CO FROM WASTE COMBUSTION USING MODIFIED SORBENT IN A FIXED BED REACTOR. Gases produced by garbage burning consist of dangerous gases such as CO, SO2 and other gases. Technology for reducing dangerous gases from incinerator outlet can be done by using a dry or wet process. The dry process is more economical process because of simple process, easy maintenance and no liquid waste as product. However, the weakness of the dry process is low absorption conversion and low gas removal efficiency. One way to overcome these problems is to use sorbent which has high reactivity. An inexpensive sorbent that commonly used is Ca(OH2. The aim of this research was to increase the reactivity of Ca(OH2 sorbent by using diatomaceous earth and compost as a source of silica and biosorbent, respectively. Diatomaceous earth contains CaO, SiO2 and Al2O3 and compost contains bacteria as a biosorbent that can convert CO to CO2 and CH4. The reaction between SiO2 and Ca(OH2 would form calcium silicate hydrate (CaO.SiO2.2H2O that has a high porosity and reactivity. The results showed that the reactivity of Ca(OH2 sorbent increased by addition of diatomaceous earth and compost. The results also showed that the sorption of CO gas increases with increasing of height of sorbent bed and temperature. The highest CO gas sorption was obtained at temperature of 150oC and sorbent bed height of 6 cm using the modified sorbent with Ca(OH2/DE/compost ratio of 3:1:1. Gas hasil pembakaran sampah terdiri dari gas-gas yang berbahaya seperti CO, SO2 dan lain sebagainya. Teknologi penghilangan gas-gas tersebut dapat dilakukan dengan menggunakan proses kering maupun proses basah. Penghilangan dengan proses kering lebih ekonomis karena sederhana, mudah pemeliharaan dan tidak menghasilkan limbah cair. Namun demikian, kelemahan proses kering adalah konversi absorpsi rendah dan efisiensi penyisihan  gas relatif kecil. Salah satu cara mengatasi masalah tersebut di atas adalah dengan

  13. UNJUK KERJA REAKTOR PLASMA DIELECTRIC BARRIER DISCHARGE UNTUK PRODUKSI BIODIESEL DARI MINYAK KELAPA SAWIT

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    Ardian Dwi Yudhistira

    2013-10-01

    Full Text Available Biodiesel is one of alternative renewable energy source to substitute diesel fuel. Various biodiesel productionprocesses through transesterification reaction with a variety of catalysts have been developed by previousresearcher. This process still has the disadvantage of a long reaction time, and high energy need. DielectricBarrier Discharge (DBD plasma electro-catalysis may become a solution to overcome the drawbacks in theconventional transesterification process. This process only needs a short time reaction and low energy process.The purpose of this study was to assess the performance of DBD plasma rector in making biodiesel such as: theeffect of high voltage electric value, electrodes gap, mole ratio of methanol / oil, and reaction time. TheResearch method was using GC-MS (Gas Cromatography-Mass Spectrofotometry and FTIR (FourierTransform Infrared Spectrofotometry and then it will be analysed the change of chemical bond betweenreactant and product. So, the reaction mechanism can be predicted. Biodiesel is produced using methanol andpalm oil as reactants and DBD plasma used as reactor in batch system. Then, reactants contacted by highvoltage electric. From the results of this research can be concluded that the reaction mechanism occurs in theprocess is the reaction mechanism of cracking, the higher of electric voltage and the longer of reaction time leadto increasing of product yield. The more of mole ratio of methanol / oil and widening the gap between theelectrodes lead to decreased product yield. From this research, product yield maksimum is 89,8% in the variableof rasio mol metanol/palm oil 3:1, voltage 10 kV, electrode gap 1,5 cm, and reaction time 30 seconds.

  14. Pengaruh Variasi Perbandingan Udara-Bahan Bakar Terhadap Kualitas Api Pada Gasifikasi Reaktor Downdraft Dengan Suplai Biomass Serabut Kelapa Secara Kontinyu

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    Sholehul Hadi

    2013-12-01

    Full Text Available Salah satu bentuk energy alternatif adalah gasifikasi biomassa. Biomas yang digunakan adalah serabut kelapa muda karena jumlahnya melipah dan belum maksimal dimanfaatkan oleh masyarakat. Gasifikasi dari serabut kelapa dijadikan syn gas untuk bahan bakar terbarukan dan dapat diperbaharui. Dengan peralatan reactor gasifikasi dapat dihasilkan (Air Fuel Ratio terbaik untuk sistem pemasukan serabut kelapa kontinyu 0,5 kg/10 menit , melalui putaran dimmer pada sentrifugal blower diberikan 4 variabel yaitu 5, 7, 9, 10. Dan memvariasikan ukuran serabut kelapa 10-50 mm dan 50-100 mm. Hasil menunjukan untuk: zona pengeringan pada temperatur (T1 sampai 100ºC, zona pirolisispada temperatur (T2 sampai 350ºC, zona oksidasi parsialpada temperatur (T3 sampai 600ºC, zona reduksipada temperatur (T4 sampai 450ºC, indikator temperatur synthetic-gas pada temperatur (T5 sampai 120ºC dan Kandungan energi terbaik ditinjau dari LHV  syn-gas dihasilkan pada variasi AFR 1,06 untuk ukuran serabut kelapa 50-100 mm dengan efisiensireaktorgasifikasi sebesar 69,87 %. Pada variasi AFR tersebut dihasilkan komposisi flammable gas sebagai berikut : CO= 20,8%, H2 = 5,34%, dan CH4 = 4,5%.Untuk variasi ini prosentase kandungan syn-gas dan laju alir massa syn-gas selama proses memiliki komposisi yang tepat sehingga visualisasi nyala api yang dihasilkan terdapat warna biru dengan suhu 3530C.

  15. PEMBUATAN BAHAN BAKU SPREADS KAYA KAROTEN DARI MINYAK SAWIT MERAH MELALUI INTERESTERIFIKASI ENZIMATIK MENGGUNAKAN REAKTOR BATCH [Preparation of Red Palm Oil Based-Spreads Stock Rich in Carotene Through Enzymatic Interesterification in Batch-type Reactor

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    Nur Wulandari1,2

    2012-12-01

    Full Text Available Enzymatic interesterification of red palm oil (a mixture of red palm olein/RPO and red palm stearin/RPS in 1:1 weight ratio and coconut oil (CNO blends of varying proportions using a non-specific immobilized Candida antartica lipase (Novozyme 435 was studied for the preparation of spread stock. The interesterification reaction was held in a batch-type reactor. Two substrate blends were chosen for the production of spread stock i.e. 77.5:22,5 and 82.5:17.5 (RPO/RPS:CNO, by weight through enzymatic interesterification in three different reaction times (2, 4, and 6 hours. The interesterification reactions were conducted at 60°C, 200 rpm agitation speed and 10% of Novozyme 435. The interesterified products were evaluated for their physical characteristics (slip melting point or SMP and solid fat content or SFC and chemical characteristics (carotene retention, moisture content, and free fatty acid/FFA content. All of the interesterified products had lower SFC and SMP as compared to the initial blends. The SMP and SFC increased in longer reaction times. The SMP ranged from 30.8°C to 34.9°C. The carotene retention ranged from 74.80% to 81.08%, while the moisture content and FFA content increased in longer reaction times. The interesterified products had desirable physical properties for possible use as a spread stock rich in carotene.

  16. Official announcement of recommendations issued by the RSK (Reactor Safety Commission) and the SSK (Radiation Protection Commission). As of 11 October 1994; Bekanntmachung von Empfehlungen der Reaktor-Sicherheitskommission und der Strahlenschutzkommission. Vom 11. Oktober 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-23

    The RSK and the SSK have found satisfactory evidence that the planned surface and underground facilities and equipment of the repository fulfill the safety requirements given, and that the planned operations for emplacement and storage can be performed with due safety. RSK and SSK put emphasis on the fact that the specific types and volumes of the radioactive wastes envisaged for storage at this site will not create a hazardous situation at any place of the entire repository as a result of temperatures, pressures or radioactivity concentrations developing during emplacement or storage, so that the repository`s hazardous potential is assessed to be very low, both in the operational phase and during the post-sealing phase. The RSK and SSK approve of the submitted safety concept for specified normal operation, as well as the submitted regime of preventive measures for protection from accidents, and the results of the accident analyses performed. Engineered and other radiation protection measures provided for specified normal operation are found to guarantee protection of the personnel, the local population and the environment. Calculated radiation doses are below the limits given in section 44, sub-section 1, and sections 45 and 49 of the Radiation Protection Ordinance (StrlSchV). The calculations submitted for emergency-induced radioactivity levels show compliance with the maximum acceptable doses laid down in section 28, sub-sec. 3 StrlSchV. The review of data submitted concerning the longterm safety of the site and the calculation approaches for determining individual doses by way of model calculations for radionuclide migration from the storage site to the biosphere are approved of by the commissions, who found evidence that the waste stored will not create hazardous radiation levels in a post-sealing operation phase extending over a period of 10.000 years. (orig./HP) [Deutsch] RSK und die SSK haben sich davon ueberzeugt, dass alle geplanten ueber- und

  17. SAFIRA. Sub-project B 1.3: Development of coupled in-situ reactors and optimisation of the geochemical processes in the discharge of different in situ reactor sytems. Final report; SAFIRA. Teilprojekt B 1.3: Entwicklung von gekoppelten in situ-Reaktoren und Optimierung der geochemischen Prozesse im Abstrom von verschiedenen in situ-Reaktor-Systemen. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Dahmke, A.; Schaefer, D.; Koeber, R.; Plagentz, V.

    2002-12-01

    The Bitterfeld ground water is contaminated with many different pollutants over a large area. Long-term measures like reactive barriers for purification are required. However, groundwater contaminated with multiple contaminants cannot be purified by a single reactive material; for this reason, the effectivity of combinations of different reactive materials was investigated. Of the combinations investigated, reducing iron and activated carbon connected in series was the most effective: The iron will remove the reducible chlorinated hydrocarbons, while the rest of the contaminants are adsorbed to the activated carbon. Iron and ORC was another interesting option, but the combination of iron and activated carbon was found to be the most favourable option. Until a better method is available, it is recommended to connect iron and activated carbon in parallel for removing contaminant mixtures. Directly behind reactive iron barriers (also when combined with activated carbon), the limiting values of the Freshwater Ordinance for Fe(II) and pH are exceeded. Directly behind ORC reactors, the limiting values for Mg and pH are exceeded. Investigations in the outflow of these reactive materials showed that the high pH values are buffered by contact with the aquifer material to values typical of aquifers, which usually are below the limiting values of the Freshwater Ordinance. However, as the buffer capacity of the soil is exhausted, a zone with a higher pH starts to grow in the aquifer. The growth of this zone depends on the pH and on the aquifer material. Especially in soils as found at Bitterfeld, with a high concentration of organic matter, we find long-term desorption of pollutants from the aquifer materials which will burden the purified water leaving the water treatment system and prohibit its utilization. [German] Der Grundwasserleiter im Raum Bitterfeld ist grossraeumig mit vielen verschiedenen Substanzen kontaminiert. Aufgrund der grossraeumigen Erstreckung kommen nur langfristig kostenguenstige passive Massnahmen wie reaktive Barrieren zur Sanierung in Frage. Grundwasser, das mit mehreren und unterschiedlich reagierenden Stoffen kontaminiert ist, kann jedoch nicht mit Hilfe eines einzelnen reaktiven Materials gereinigt werden, daher wurde die Effektivitaet von Kombinationen unterschiedlicher reaktiver Materialien zur Sanierung untersucht. Von den untersuchten Kombinationen erwies sich die Hintereinanderschaltung von reduzierendem Eisen und Aktivkohle als besonders effektiv. Reduzierbare chlorierte Kohlenwasserstoffe werden im Eisen entfernt, die verbleibenden Kontaminanten adsorbieren auf der Aktivkohle. Auch die Hintereinanderschaltung von Eisen und Sauerstoff abgebenden ORC, in denen ein aerober mikrobieller Abbau statt findet, ist zur Entfernung von Mischkontaminationen geeignet. Eine Kostenschaetzung zeigt, dass die Kombination von Eisen und Aktivkohle in Abhaengigkeit von der Zusammensetzung der Kontamination guenstiger als Aktivkohle allein sein kann und generell guenstiger als die Kombination von Eisen und ORC ist. Ohne ein guenstigeres Verfahren zum Einbringen von Sauerstoff in den Aquifer wird die Hintereinanderschaltung von Eisen und Aktivkohle zur Sanierung von Mischkontaminationen empfohlen. Im direkten Abstrom von reaktiven Eisenbarrieren (auch in Kombination mit Aktivkohle) sind die Grenzwerte fuer Fe(II) und pH entsprechend der Trinkwasserverordnung ueberschritten. Im Abstrom von ORC-Reaktoren werden die zulaessigen Werte fuer Mg und pH ueberschritten. Untersuchungen im Abstrom dieser reaktiven Materialien zeigen, dass die hohen pH-Werte durch den Kontakt mit dem Aquifermaterial auf Aquifer-typische Werte gepuffert werden, die ueblicherweise unter den Grenzwerten der Trinkwasserverordnung liegen. Mit Erschoepfen der Pufferkapazitaet des Bodens breitet sich jedoch eine Zone mit erhoehtem pH-Wert im Aquifer aus. Die Geschwindigkeit dieser Ausbreitung haengt vom pH-Wert und dem Aquifermaterial ab. Gerade fuer sehr Organik reiche Boeden wie in Bitterfeld wird auch eine lange anhaltende Desorption von Schadstoffen a

  18. Earthquake experiments at the HDR (Heissdampf Reaktor) test facility using an eccentric mass vibrator

    International Nuclear Information System (INIS)

    As part of he earthquake investigations carried out by the Karlsruhe Nuclear Research Center, Project HDR, at the HDR Test Facility near Frankfurt/Main, high level shaker test were performed during June/July 1986. The purpose of these tests, supported by the German and U.S. governments was to investigate full scale structural response involving significant concrete and soil strain as well as strong indirect excitation of vessels, pipes and other mechanical equipment. The calculational efforts included predictions of the building and piping response stress analyses. Within these test series, the reactor building was brought to its ultimate loading capacity. (author)

  19. Parogenerátory tlakovodních reaktorů

    OpenAIRE

    Michalica, Martin

    2015-01-01

    Tato bakalářská práce se zabývá popisem jednotlivých konstrukčních řešení parogenerátorů. V první části bakalářské práce je popsán počátek jaderného průmyslu v Rusku. Samostatná práce se věnuje jednotlivým konstrukčním řešením. Poslední kapitola detailně popisuje jednotlivé části parogenerátoru VVER 1000. Součástí práce je tvorba 3D modelu parogenerátoru VVER 1000, který bude sloužit jako učební pomůcka v projektu Cenelín. This bachelors thesis describes various designs of steam generators...

  20. PERFORMA OKSIDASI METAN PADA REAKTOR KONTINYU DENGAN PENINGKATAN KETEBALAN LAPISAN BIOCOVER LANDFILL

    OpenAIRE

    Opy Kurniasari; Tri Padmi; Edwan Kardena; Enri Damanhuri

    2013-01-01

    PERFORMANCE OF METHANE OXIDATION IN CONTINUOUS REACTOR BY BIOCOVER LANDFILL FILM THICKNESS IMPROVEMENT. Municipal solid waste (MSW) handling in Indonesia is currently highly dependent on landfilling at the final disposal facility (TPA), which generally operated in layer-by-layer basis, allowing the anaerobic (absent of oxygen) process. This condition will certainly generate biogas in the form of methane (CH4) and CO2. Methane is a greenhouse gas with a global warming potential greater than CO...

  1. UNJUK KERJA REAKTOR PLASMA DIELECTRIC BARRIER DISCHARGE UNTUK PRODUKSI BIODIESEL DARI MINYAK KELAPA SAWIT

    OpenAIRE

    Ardian Dwi Yudhistira; Istadi Istadi

    2013-01-01

    Biodiesel is one of alternative renewable energy source to substitute diesel fuel. Various biodiesel productionprocesses through transesterification reaction with a variety of catalysts have been developed by previousresearcher. This process still has the disadvantage of a long reaction time, and high energy need. DielectricBarrier Discharge (DBD) plasma electro-catalysis may become a solution to overcome the drawbacks in theconventional transesterification process. This process only needs a ...

  2. Perancangan dan Simulasi MRAC untui Proses Pengendalian Temperatur pada Continuous Stirred Tank Reactor (CSTR

    Directory of Open Access Journals (Sweden)

    Amelia Sylvia

    2014-03-01

    Full Text Available Temperatur merupakan salah satu variabel proses dasar yang dikendalikan untuk menjaga suhu cairan di dalam reaktor. Model Reference Adaptive Controller (MRAC dengan MIT rule dipilih untuk mencapai spesifikasi respon yang diinginkan pada CSTR. Beban yang bervariasi berupa debit aliran likuid yang masuk ke dalam reaktor dapat menyebabkan perubahan parameter yang mempengaruhi perubahan temperatur output produk pada CSTR. Sebuah simulasi dilakukan dengan menggunakan MATLAB dan hasilnya dianalisa. Respon plant dapat melakukan adaptasi parameter – parameter kontrolernya cukup baik pada nilai gain adaptasi dengan rentang 0.00000010000 sampai 0.00000000001. Waktu yang dibutuhkan untuk mengatasi beban yang bervariasi berupa debit aliran yang masuk ke dalam reaktor dengan nilai yang maksimal (1.5 m^3/min menghasilkan respon plant lebih cepat 42 detik dari pada debit aliran masuk dengan nilai yang nominal (1 m^3/min 63 detik dan minimal (0.5 m^3/min 75 detik.

  3. PENGARUH GEMPA PATAHAN LEMBANG TERHADAP FLEKSIBILITAS PIPA DAN KEGAGALAN NOZEL PERALATAN SISTEM PENDINGIN PRIMER REAKTOR TRIGA 2000 BANDUNG

    OpenAIRE

    H.P. Raharjo

    2012-01-01

    Gempa bumi di suatu instalasi nuklir dapat menyebabkan terjadinya kerusakan sistem peralatan karena adanya perubahan fleksibilitas pipa akibat beban berlebih pada sistem perpipaannya. Beban dari sistem perpipaan dapat membebani nozel peralatan seperti pompa, penukar panas, dll. Apabila beban tersebut terlalu besar dan melebihi beban yang diizinkan akan mengakibatkan kegagalan nozel peralatan. Penelitian ini menganalisis besarnya beban-beban yang terjadi di semua nozel  sistem pendingin prime...

  4. Proses Pembuatan Biodiesel dari Palm Fatty Acid Distillate (PFAD) dan Dimethyl Carbonate dengan Reaktor Packed Bed Menggunakan Katalis Novozym® 435

    OpenAIRE

    Senjaya, Johan

    2016-01-01

    Palm Fatty Acid Distillate (PFAD) is a byproduct produced in the refining process in the palm oil that could potentially be a raw material in the manufacturing process of biodiesel and the price is much cheaper than virgin oil. The purpose of this study was to utilize PFAD in the manufacture of biodiesel by using Dimethyl Carbonate (DMC) as the reactant and Novozym® 435 as a catalyst. The production of biodiesel is done in two ways which are batch and continuous. For batch, PFA...

  5. The Siemens-Argonaut reactor as a driver zone for a high-temperature reactor cell. Der Siemens-Argonaut-Reaktor als Treiberzone fuer eine Hochtemperaturreaktorzelle

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, H.; Schuerrer, F.; Ninaus, W.; Oswald, K.; Rabitsch, H.; Kreiner, H. (Technische Univ., Graz (Austria). Inst. fuer Theoretische Physik und Reaktorphysik); Neef, R.D. (Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Reaktorentwicklung)

    1984-12-15

    To enable a validation of neutron physics calculation methods for pebble bed reactors the inner reflector of an Argonaut research reactor was substituted by a full of about 1200 fuel elements of the AVR-Juelich type. The report describes the measuring instruments and the reactor physical layout of the arrangement by the code packages GAMTEREX, ZUT-D.G.L. and MUPO. Comparison of calculated reaction rates with measurements show good agreement. Application of the codes to high-temperature reactors in abnormal states is envisaged. (Author, translated by G.Q.)

  6. Svar til: Hvorfor bryder robotter sammen i Tjernobyl-reaktor? (Ingeniøren, lørdag d. 17 nov. 2007)

    DEFF Research Database (Denmark)

    Morgen, Per

    2007-01-01

    Symposium 'Image Engineering and Vision Metrology'. Det er kendt af folk, der beskæftiger sig med mikroelektronik, at computerchips og hukommelseskredse kan blive sat ud af spillet, når de bliver udsat for radioaktivitet, og derfor vil også en computerstyret robot være sårbar overfor dette. Radioaktiv...... fra Århus Universitet, af N. Bassler: Radiation damage in scientific chargecoupled devices. Master's Thesis, Institute of Physics and Astronomy, University of Aarhus, Aarhus, Denmark (fra 2002). Konlusionen af deres undersøgelser er, at radioaktiv stråling (de undersøger gammastråling, som der må...

  7. The vegetation as sink and biochemical reactor for airborne pollutants. Final report; Die Vegetation als Senke und biochemischer Reaktor fuer luftgetragene Schadstoffe. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Weissflog, L.; Wenzel, K.D. [UFZ - Umweltforschungszentrum Leipzig-Halle GmbH, Leipzig (Germany). Sektion Chemische Oekotoxikologie

    1997-06-30

    The present project involved extensive studies on the air pollution situation and interactions between organic as well as inorganic air pollutant levels and the vegetation in three east German states. Seven monitoring sites with different emission profiles were selected in Saxony-Anhalt, one typically polluted site in Saxony, and two less polluted sites in Mecklenburg-Western Pomerania. The following emitter types were found to exhibit consistent pollutant patterns: landfills receiving chloroorganic special wastes; hard-coal-fuelled firing installations; commercial charcoal plants; industry; industry - car traffic - domestic fuel combustion; car traffic. [Deutsch] Im Verlauf der Projektarbeiten wurden an sieben durch unterschiedliche Emittententypen belasteten Standorten in Sachsen-Anhalt, einem typisch belasteten Standort in Sachsen und an zwei weniger belasteten Standorten in Mecklenburg/Vorpommern umfangreiche Untersuchungen zur Immissionssituation und der Wechselwirkung der luftgetragenen anorganischen und organischen Schadstofffracht mit der Vegetation durchgefuehrt. Dabei konnten fuer folgende Emittenten charakteristische Schadstoffmuster ermittelt werden: - Deponien mit chlororganischem Sondermuell - Feuerungsanlagen fuer Steinkohle - Gewerbliche Anlagen zur Herstellung von Holzkohle - Industrie - Industrie/Kfz-Verkehr/Hausbrand - Kfz-Verkehr. (orig.)

  8. Pengaruh Rasio Udara Pembakaran Antara Udara Primer Dan Sekunder Terhadap Efisiensi Pembakaran Serat Buah Sawit Pada Reaktor Pembakaran Fixed-Bed

    OpenAIRE

    Yudanto, Bagus Giri

    2012-01-01

    Study of the oil palm fiber (mesocarp) combustion process in the laboratory scale has been conducting. The purpose of this research was to known the effect of various combustion air ratio between primary air (PA) and secondary air (SA) to combustion qualities of mesocarp. The ratio of combustion air (PA:SA) were variated at (20:80), (35:65), (50:50), (65:35) and (80:20). The research experimental was conducted using by a fixed bed reactor. The Controlling of combustion air flow rate using by ...

  9. Development of a continuous process for microbial elimination of 1,2 dichloropropane in contaminated water; Entwicklung eines kontinuierlichen Verfahrens zur mikrobiellen Elimination von 1,2-Dichlorpropan in kontaminierten Waessern

    Energy Technology Data Exchange (ETDEWEB)

    Hauck, R.

    2000-07-01

    methanogenes and sulfate reducing bacteria resulted in a slower but continued DCP degradation. Due to these results molecular hydrogen was spiked to the reactor whereby an increase of DCP degradation could be achieved. The applied culture showed a high dechlorination potential towards different aliphatic and aromatic chloroorganics, so that an application of the presented technique for groundwater treatment is principally suitable. (orig.) [German] Fuer die Untersuchungen zum biologischen Abbau von 1,2-Dichlorpropan (DCP) wurden sowohl aerobe als auch anaerobe batch- und kontinuierliche Reaktorversuche mit Mischkulturen durchgefuehrt. Fuer die aeroben Versuche wurde eine Mischkultur aus einem mit chlororganischen Stoffen belasteten Grundwasser angereichert und batch-Versuche zur Bestimmung der Cosubstratbeduerfnisse durchgefuehrt. Hierbei konnte jedoch kein wiederholter DCP-Abbau etabliert werden. Fuer die Realisierung des anaeroben DCP-Abbaus wurde eine Mischkultur aus Sedimenten der Saale angereichert. Im sedimenthaltigen batch-Versuch wurde die quantitative Bildung von Propen ermittelt, wobei auch geringe Mengen 1- und 2-Monochlorpropan waehrend des Abbaus nachgewiesen werden konnten. Die Mischkultur aus der Saale wurde auf Polyurethanschaumstoff-Wuerfel immobilisiert und in einem kontinuierlichen Wirbelbettreaktor etabliert. In batch- und Reaktorversuchen wurden unterschiedliche Elektronendonoren eingesetzt, wobei sich Methanol mit einer maximalen DCP-Eliminationsrate von 65 mg/(l x d) als das den Abbau am besten unterstuetzende Einzelsubstrat erwies. Die maximal im Reaktor erreichbaren Eliminationsraten von 90 mg/(l x d) bei einer Verweilzeit von 24 h und DCP-Zulaufkonzentrationen von 100 mg/l wurden mit einer Elektronendonorkombination aus Methanol und Acetat erzielt. Die Charakterisierung der Population durch molekularbiologische Analysen ergab, dass sich im Laufe des Reaktorbetriebs eine Spezies mit hoher 16S rRNA-Sequenzhomologie zu Dehalobacter restricuts in der

  10. Modeling and simulation of a biogas reactor; Modellierung und Simulation eines Biogasreaktors

    Energy Technology Data Exchange (ETDEWEB)

    Muha, Ivo

    2012-11-22

    The anaerobic fermentation describes the decomposition of organic material in the absence of oxygen and consists four phases of the process (hydrolysis, acidogenesis, acetogenesis and methanogenesis). In this work, the distribution of these four phases of the process could be determined exactly on both stages of a two-stage two-phase biogas reactor. The distribution is of crucial importance for future work, as this can be determined exactly which substances must be taken into account in the measurements and in the modeling. In 2002, the IWA Task Group published the ADM1 model, which takes into account all four process stages of anaerobic fermentation. In the present work, a spatially resolved model for the anaerobic fermentation is developed, in which the ADM1 model is coupled with a flow model. Subsequently, a reduced simulation model for acetoclastic methanogenesis in a two-stage two-phase biogas reactor is created. Based on measurement data the decomposition of methane to acetic acid in the reactor by the simulation model can be reproduced well. Subsequently, the validated model is used to affiliate rules for optimal control of the reactor and furthermore, the efficiency of the reactor is determined by the local production of methane. The information obtained can be used to optimize the biogas reactor. [German] Die anaerobe Fermentation beschreibt den Abbau organischen Materials unter Ausschluss von Sauerstoff und setzt sich aus vier Prozessphasen (Hydrolyse, Acidogenese, Acetogenese und Methanogenese) zusammen. Im Rahmen dieser Arbeit konnte die Aufteilung dieser vier Prozessphasen auf die beiden Stufen eines zweistufigen zweiphasigen Biogas-Reaktors genau bestimmt werden. Die Aufteilung ist von entscheidender Bedeutung fuer zukuenftige Arbeiten, da dadurch genau festgelegt werden kann, welche Stoffe bei den Messungen und bei der Modellierung beruecksichtigt werden muessen. Im Jahre 2002 wurde von der IWA Taskgroup das ADM1-Modell, welches alle vier

  11. Studio 1:1

    Index Scriptorium Estoniae

    2011-01-01

    Projekteerimis- ja disainistuudiost STUDIO 1:1 (Eindhoven), mis tegeleb avaliku ruumi loomise ja selle kasutamise kujundamisega. Projektidest "Linnulinn - linn lindude segakogukonna jaoks" ja ICT kogemuskeskus "De Verdieping"

  12. WOOD 1:1

    DEFF Research Database (Denmark)

    2013-01-01

    Report from 1:1 workshop at Virserum Konsthall in May 2013 with a team of Master's students from Royal Academy of Fine Arts, School of Architecture, Dpt. 3.......Report from 1:1 workshop at Virserum Konsthall in May 2013 with a team of Master's students from Royal Academy of Fine Arts, School of Architecture, Dpt. 3....

  13. STUDI MODEL ALIRAN FLUIDA DAN PERPINDAHAN PANAS PADA PBMR.

    Directory of Open Access Journals (Sweden)

    Achmad Fatich Al-Qodri

    2013-11-01

    Full Text Available Reaktor tipe Pebble bed merupakan opsi yang menjanjikan untuk teknologi reaktor generasi mendatang dan memiliki potensi untuk memberikan pembangkitan listrik dengan efisiensi tinggi dan murah.Perpindahan panas reaktor ini menghadapi kendala akibat kompleksitas yang berkaitan dengan desain aliran panas.Dengan demikian, untuk mensimulasikan secara baik aliran dan perpindahan panas reaktor modular pebble bed ini memerlukan suatu model perpindahan panas yang berhubungan dengan radiasi serta konveksi dan konduksi panas.Dalam studi ini, suatu model dengan kemampuan untuk mensimulasikan aliran fluida dan perpindahan panas dalam teras reaktor modular pebble bed telah dikembangkan.Model ini diterapkan pada suatu personal computer (PC yang menggunakan program komputer Matlab r2008a Versi 7.1.Beberapa parameter penting aliran fluida dan perpindahan panas telah dipelajari, termasuk penurunan tekanan (pressure drop di teras reaktor, koefisien perpindahan panas, bilangan Nusselt, dan konduktivitas panas efektif pebble bahan bakar. Hasil yang diperoleh dari percobaan simulasi menunjukkan adanya suatu tekanan yang merata pada arah radial untuk suatu rasio diameter teras terhadap elemen bakar (D/d > 20 dan koefisien perpindahan panas meningkat seiring dengan peningkatan temperatur dan laju alir massa pendingin. Model ini dapat menjelaskan secara memadai fenomena aliran panas dan perpindahan panas dan kehilangan tekanan melalui friksi dalam PBMR tipe pebble bed.Kata kunci: Aliran fluida, perpindahan panas, PBMR, packed bed, penurunan tekananAbstractThe pebble bed type high temperature gas cooled nuclear reactor is a promising option for next generation reactor technology and has the potential to provide high efficiency and cost effective electricity generation. The reactor unit heat transfer poses a challenge due to the complexity associated with the thermalflow design. Therefore to reliably simulate the flow and heat transport of the pebble bed modular reactor

  14. The development of fast reactors - Effects on the Swedish system of management of spent fuel; Utveckling av snabba reaktorer - Paaverkan paa det svenska systemet foer hantering av anvaent braensle

    Energy Technology Data Exchange (ETDEWEB)

    Hans Forsstroem, Hans [SKB International AB, Stockholm (Sweden)

    2013-09-15

    Since the start of the nuclear power era studies have been performed of how to utilise the uranium energy resource in the most effective way. Only about one percent of the energy potential of uranium is utilised in the light water reactors of today. To improve the utilization other types of reactors are needed. With fast reactors theoretically 50-100 times more energy can be extracted from the uranium. This will require reprocessing of the uranium and multiple recycling of the plutonium. Plutonium and uranium can also be recycled in light water reactors, but this will only improve the uranium utilisation by about 20 %. Recycling of plutonium on a routine basis is presently only done in France. The development of fast reactors has been going on since the end of the 1940ies. During the 1970ies the planning was that a large number of fast reactors and their associated fuel cycle facilities would be in operation by the year 2000. The development has, however, for different reasons been much slower than planned. The general assessment today is that fast reactor, if they will be realised, will hardly give an important contribution to energy production until after 2050. Nuclear power production has instead been dominated by light water reactors similar to the ones in use in Sweden. Light water reactors are believed to continue to dominate during the next decades. To start a fast reactor system plutonium (or highly enriched uranium) will be needed. Such plutonium is contained in spent nuclear fuel from light water reactors. This raises the question: Should the spent nuclear fuel be stored so that the potential energy resource in the fuel can be used in the future instead of disposing of it as a waste? The answer to this question will depend on when the material will be useful, i.e. when fast reactors have been introduced on a large scale. It will also depend on the demand for plutonium at this time, i.e. will plutonium be a scarce redundant resource at this point of time. In this context it should be considered that fast reactors will generate their own plutonium, as breeder reactors. Plutonium from other reactors will thus only be needed for the first years of operation. To provide a basis for the answer to the question if the Swedish spent fuel is a resource or a waste this report provides an overview of the present development status for fast reactors and their potential for large scale commercial use. It further describes the impact on the Swedish system for management of spent nuclear fuel if the fuel were to be reprocessed and the uranium and plutonium reused as fuel for fast reactors or for the present reactors.

  15. NPP Grafenrheinfeld. No thank you. Questions and answers concerning the oldest operating crack susceptible reactor in the federal republic; AKW Grafenrheinfeld. Nein danke. Fragen und Antworten zum aeltesten noch laufenden und rissanfaelligsten Reaktor der Republik

    Energy Technology Data Exchange (ETDEWEB)

    Darge, Tobias

    2014-03-15

    The brochure discusses questions on the NPP Grafenrheinfeld. concerning the following issues: reactor type, operating company, nuclear fuel, licensing, radioactive waste management, susceptibility to damage, stress test results, critical arguments concerning the reactor pressure vessel steel and the containment, cracks in the primary circuit, safety in case of an aircraft crash, possibility of a severe accident, consequences of a severe accident, medical emergency plan, public information for an emergency case, shutdown at the end of 2015, necessity of a new power plant for energy security?.

  16. Report on the interpretation of critical experiments in the Siemens-Argonaut-Reactor Graz to study water ingress into spherical elements. Ergebnisbericht zur Auslegung kritischer Experimente am Siemens-Argonaut-Reaktor Graz zum Studium des Wassereinbruches im Kugelhaufen

    Energy Technology Data Exchange (ETDEWEB)

    Schuerrer, F. (Technische Univ., Graz (Austria). Inst. fuer Theoretische Physik und Reaktorphysik); Neef, R.D. (Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Reaktorentwicklung)

    1979-04-15

    The experiments described are of interest in the study of water contamination in HTR fuel elements. The Siemens Argonaut Reactor (SAR) has been considered as a research tool for a simulation experiment. Following a brief description of the SAR, planned programs are discussed in 'dry' and 'wet' cores. Detector foil types and locations are noted. A theoretical model is developed and nuclide concentrations estimated in the various spectral zones. Reactivity calculations have been made and are summarised for various H{sub 2}O percentage concentrations. The discussion is supported by simplified core layout diagrams and graphs of core flux distributions. Neutron diffusion and spectra calculations are referenced to computer programs used by KFA-Juelich, published elsewhere, and include GAM, THERMOS, MUPO and EXTERMINATOR-2. (G.C.)

  17. Untersuchungen zur CO-Oxidation und Wassergas-Shift Reaktion an Au/TiO2 und Au/CeO2 Katalysatoren - Aufbau eines Niederdruck- und eines Temporal Analysis of Products Reaktors

    OpenAIRE

    Leppelt, Rainer

    2007-01-01

    The reaction order for the WGS reaction over Au/CeO2 was determined. The influence of the Au content was studied on eight catalysts with increasing gold loading. The apparent activation energy for all catalysts was determined to be 40 ± 3 kJ/mol. In DRIFTS measurements formates and carbonates were identified as main surface species. The decomposition rate of formates is the same as the reaction rate and therefore the decomposition of formates is regarded as rate limiting step. By TPD-experime...

  18. Development of a methodology for safety classification on a non-reactor nuclear facility illustrated using an specific example; Entwicklung einer Methodik zur Sicherheitsklassifizierung fuer eine kerntechnische Anlage ohne Reaktor an einem spezifischen Beispiel

    Energy Technology Data Exchange (ETDEWEB)

    Scheuermann, F.; Lehradt, O.; Traichel, A. [NUKEM Technologies Engineering Services GmbH, Alzenau (Germany)

    2015-07-01

    To realize the safety of personnel and environment systems and components of nuclear facilities are classified according to their potential danger into safety classes. Based on this classification different demands on the manufacturing quality result. The objective of this work is to present the standardized method developed by NUKEM Technologies Engineering Services for the categorization into the safety classes restricted to Non-reactor nuclear facilities (NRNF). Exemplary the methodology is used on the complex Russian normative system (four safety classes). For NRNF only the lower two safety classes are relevant. The classification into the lowest safety class 4 is accordingly if the maximum resulting dose following from clean-up actions in case of incidents/accidents remains below 20 mSv and the volume activity restrictions of set in NRB-99/2009 are met. The methodology is illustrated using an example. In short the methodology consists of: - Determination of the working time to remove consequences of incidents, - Calculation of the dose resulting from direct radiation and due to inhalation during these works. The application of this methodology avoids over-conservative approaches. As a result some previously higher classified equipment can be classified into the lower safety class.

  19. New methods for characterisation of coal dust combustion characteristics at elevated pressures; Neue Methoden zur Charakterisierung des Verbrennungsverhaltens von Kohlenstaub bei erhoehtem Druck

    Energy Technology Data Exchange (ETDEWEB)

    Hackert, G.; Kremer, H.; Wirtz, S. [Bochum Univ. (Germany). Lehrstuhl fuer Energieanlagentechnik; Bonn, B.; Seewald, H. [DMT-Gesellschaft fuer Forschung und Pruefung mbH, Essen (Germany)

    1998-12-31

    DMT constructed and operates a newly designed high temperature, high pressure drop tube furnace KOALA. In co-operation with LEAT drop tube investigations of coal particle combustion were performed at temperatures up to 1 500 C and pressures up to 20 bar. In addition to conventional gas and ash analysis LEAT developed new methods of in-situ particle observation based on Phase Shift Doppler Anemometry (PDA) and a high-resolution video camera technique TOSCA. The temperature of burning particles can be determined from one particle image only. It is the aim of this work, both to produce data for the mathematical modelling and simulation of full scale pressurized combustors, and to improve the understanding of the elementary reactions in pulverised coal combustion at such conditions. (orig.) [Deutsch] Die DMT hat seit einiger Zeit den Hochtemperatur-Hochdruck-Fallrohrreaktor KOALA in Betrieb, an dem in Zusammenarbeit mit dem LEAT Verbrennungsvorgaenge von Kohlenstaub bei Druecken bis zu 20 bar und Ofenwandtemperaturen bis 1 500 C untersucht werden. Neben der Bestimmung des Verbrennungsumsatzes mit herkoemmlichen Analyseverfahren wie Gasanalyse und Reststoffanalyse werden an dem Reaktor auch optische Messmethoden wie PDA und die vom LEAT neu entwickelte bildverstaerkte, hochaufloesende Kameratechnik (TOSCA) fuer in situ Messung der brennenden Partikel eingesetzt. Auf diese Weise ist es moeglich, die Geschwindigkeitsverteilung der Kohlepartikel, ihre Groesse und Form sowie ihre Oberflaechentemperaturen im Reaktor zu bestimmen. Diese Daten fliessen in ein verbessertes kinetisches Simulationsmodell der gleichzeitigen Pyrolyse und Verbrennung der Kohle unter Druck ein. (orig.)

  20. Juba teine "1+1 = 1"

    Index Scriptorium Estoniae

    2004-01-01

    15. III Okupatsioonimuuseumis toimuva "1+1=1" teise ürituse kavast. Presentatsioonide õhtu keskendub konkreetse ruumikogemuse vahendamisele kunstis (helis, slaidi-installatsioonis, tänava-aktsioonis, skulptuuris, videos, filmis). Esinevad Cevdet Erek, Andres Lõo, Andres Kurg (arhitektuur ja interjöörid Marko Raadi filmis "Agent Sinikael") jt.

  1. Analysis of changes in the chemical composition of the blast furnace coke at high temperatures

    Directory of Open Access Journals (Sweden)

    A. Konstanciak

    2012-12-01

    Full Text Available Purpose: The main purpose of this paper was to analyze the behavior of coke in the blast furnace. The analysis of changes in chemical composition of coke due to impact of inert gas and air at different temperatures was made. The impact of the application of the thermoabrasion coefficient on the porosity of coke was also analyzed.Design/methodology/approach: By applying the Computer Thermochemical Database of the TERMO system (REAKTOR1 and REAKTOR3 three groups of substances can be distinguished. The chemical composition of blast furnace coke and the results of calculations of changes of chemical composition of coke heat treated under certain conditions were compared. The structural studies of these materials were presented.Findings: The results of the analysis of ash produced from one of Polish cokes was taken for consideration. This is not the average composition of Polish coke ashes, nevertheless it is representative of most commonly occurring chemical compositions.Practical implications: Thanks to the thermochemical calculations it is possible to predict ash composition after the treatment in a blast furnace. Those information was crucial and had an actual impact on determining the coke quality.Originality/value: Presentation of the analytical methods which, according to author, can be very useful to evaluate and identify the heat treatment for blast furnaces cokes. The research pursued represents part of a larger project carried out within the framework of Department Extraction and Recycling of Metals, Czestochowa University of Technology.

  2. Prediksi Potensi Pencemaran Pengolahan Sampah dengan Metode Gasifikasi Fluidized Bed (Studi Kasus: TPA Benowo, Surabaya

    Directory of Open Access Journals (Sweden)

    Lailatun Nikmah

    2013-03-01

    Full Text Available Sistem pengelolaan sampah di TPA Benowo masih bersistem open dumping dan belum memperhatikan dampak pencemaran terhadap lingkungan. Kuantitas sampah yang masuk ke TPA sebesar 461.705,782 ton pada tahun 2012. Kuantitas sampah diperkirakan meningkat sebanding dengan pertumbuhan penduduk, sehingga dibutuhkan skenario pengolahan sampah yang ramah lingkungan. Skenario pengolahan sampah yang akan dikaji adalah gasifikasi  fluidized bed. Potensi pencemaran gasifikasi  fluidized bed akan dikaji menggunakan metode Life Cycle Assessment (LCA dengan software SimaPro versi 7.1. Satu ton sampah pada studi ini ditentukan sebagai satu fungsi unit. Data input Life Cycle Inventory (LCI meliputi jumlah sampah yang masuk ke reaktor gasifikasi dan energi yang dibutuhkan pada proses gasifikasi berdasarkan pendekatan efisiensi reaktor gasifikasi. Penentuan nilai Life Cycle Impact Assesment (LCIA meliputi Global Warming Potential (GWP dan asidifikasi menggunakan metode Environmental Product Declarations (EPD 2008. Besar dampak dinyatakan dalam faktor emisi yang ekivalen. Kesimpulan pada penelitian ini menunjukkan bahwa skenario pengolahan sampah dengan metode gasifikasi fluidized bed memberikan dampak GWP sebesar 1067,8 kg CO2/fu pada fase start-up dan 875 kg CO2/fu pada fase energy recovery serta asidifikasi sebesar 5,93 kg SO2/fu pada fase start-up dan 4,81 kg SO2/fu pada fase energy recovery.

  3. Heteroepitaxy of CdTe(1 1 1)B on Si(1 1 1) : As

    Science.gov (United States)

    Schick, H.; Bensing, F.; Hilpert, U.; Richter, U.; Hansen, L.; Wagner, J.; Wagner, V.; Geurts, J.; Waag, A.; Landwehr, G.

    2000-06-01

    In order to improve the structural quality of CdTe/Si composite substrates, we have investigated the MBE growth mechanisms of CdTe(1 1 1) onto planar and vicinal arsenic-passivated Si(1 1 1) surfaces. The films were characterized by in situ RHEED, X-ray diffraction, Raman spectroscopy, photoluminescence, secondary electron microscopy, transmission electron microscopy and atomic force microscopy. Rocking curves had peaks narrower than 100 arcsec at a layer thickness of only 1-2 μm. BeTe buffer layers did not show a dominant effect, whereas the twin content decreased drastically when misoriented substrates were used. Efficient twin suppression can be obtained by realizing an interface step alignment between substrate and epitaxial CdTe film.

  4. Neurofibromatosis-1

    Science.gov (United States)

    ... of skin ( subcutaneous tissue) Nerves from the brain (cranial nerves) and spinal cord (spinal root nerves) Causes NF1 ... affect the appearance and put pressure on nearby nerves or organs Many soft tumors on the skin or deeper in ...

  5. 1/N

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, S.

    1980-03-01

    There exist families of field theories with symmetry group SO(N) (or SU(N)) that become simpler as N becomes larger. More precisely, the solutions to these theories possess an expansion in powers of 1/N. This expansion is the subject of these lectures. The 1/N expansion can be used to analyze model field theories. The 1/N expansion is developed for phi/sup 4/ theory and applied to two two-dimensional models with similar combinatoric structures, the Gross-Neveu model and the CP/sup N-1/ model. These models display (in the leading 1/N approximation) such interesting phenomena as asymptotic freedom, dynamical symmetry breaking, dimensional transmutation, and non-perturbative confinement. It is possible that the 1/N expansion, with N the number of colors, might fruitfully be applied to quantum chromodynamics. Unfortunately, it is not possible to make a decisive test of the approximation, because no one knows how to compute even the first term in the expansion in closed form. However, it is possible to argue that this first term, whatever its detailed form, has many properties that are also shared by the real world, and which are otherwise underived from field theory. These include the saturation of scattering amplitudes by an infinite number of narrow resonances, the essential feature of dual-resonance models. (RWR)

  6. 1. Introduction

    OpenAIRE

    Olaniyi, Rasheed

    2013-01-01

    1.1: Background to the Study According to the Safer Cities Programme of UN-Habitat, crime does not occur spontaneously but it grows out of an unequal and exclusive society, and out of a lack of institutional and social control. African cities could be described as places of fear, where violence and crime rule. As Alan Mabin observed, social life and urban economies are often organised around the fear of violence and crime (Mabin, 2004). The criminal justice system, including the police, court...

  7. Danida1

    DEFF Research Database (Denmark)

    Henriksen, Mogens

    1996-01-01

    At the request of Danish Ministry of Foreign Affairs, Department TSA.4, electrical testing of possibly damaged cables has been evaluated. This matter concerns three different types of cable, which are10 km 30(36) kV XLPE armoured submarine power cable, 1-phase15 km 30(36) kV XLPE armoured...... underground power cable, 1-phase20 km 10(12) kV XLPE armoured underground power cable, 3-phase.The possible damage of said cables took place during shipment from Denmark to Bangladesh....

  8. Pentacene on Au(111), Ag(111) and Cu(111): From physisorption to chemisorption

    Science.gov (United States)

    Lu, Meng-Chao; Wang, Rong-Bin; Yang, Ao; Duhm, Steffen

    2016-03-01

    We measured the electronic and the molecular surface structure of pentacene deposited on the (111)-surfaces of coinage metals by means of ultraviolet photoelectron spectroscopy (UPS) and low-energy electron diffraction (LEED). Pentacene is almost flat-lying in monolayers on all three substrates and highly ordered on Au(111) and on Cu(111). On Ag(111), however, weak chemisorption leads to almost disordered monolayers, both, at room temperature and at 78 K. On Cu(111) pentacene is strongly chemisorbed and the lowest unoccupied molecular orbital becomes observable in UPS by a charge transfer from the substrate. On Ag(111) and Cu(111) multilayers adopt a tilted orientation and a high degree of crystallinity. On Au(111), most likely, also in multilayers the molecular short and long axes are parallel to the substrate, leading to a distinctively different electronic structure than on Ag(111) and Cu(111). Overall, it could be demonstrated that the substrate not only determines the geometric and electronic characteristics of molecular monolayer films but also plays a crucial role for multilayer film growth.

  9. Pentacene on Au(111), Ag(111) and Cu(111): From physisorption to chemisorption

    International Nuclear Information System (INIS)

    We measured the electronic and the molecular surface structure of pentacene deposited on the (111)-surfaces of coinage metals by means of ultraviolet photoelectron spectroscopy (UPS) and low-energy electron diffraction (LEED). Pentacene is almost flat-lying in monolayers on all three substrates and highly ordered on Au(111) and on Cu(111). On Ag(111), however, weak chemisorption leads to almost disordered monolayers, both, at room temperature and at 78 K. On Cu(111) pentacene is strongly chemisorbed and the lowest unoccupied molecular orbital becomes observable in UPS by a charge transfer from the substrate. On Ag(111) and Cu(111) multilayers adopt a tilted orientation and a high degree of crystallinity. On Au(111), most likely, also in multilayers the molecular short and long axes are parallel to the substrate, leading to a distinctively different electronic structure than on Ag(111) and Cu(111). Overall, it could be demonstrated that the substrate not only determines the geometric and electronic characteristics of molecular monolayer films but also plays a crucial role for multilayer film growth. (paper)

  10. Dynamics Explorer-1 (DE-1)

    Science.gov (United States)

    Gordon, F.; Pashby, P.

    1991-01-01

    The Dynamics Explorer (DE) mission is designed to study the Earth's electromagnetic fields at varying heights up to 4 Earth radii. The DE-1 was launched on a Delta 3913 launch vehicle from the Western Test Range and was placed in a 561 x 23279 km orbit with a 90 degree inclination. The Deep Space Network (DSN) began to support this extended mission on February 1, 1985. Coverage consists of five passes per day that last for 45 minutes each. Information is given in tabular form for DSN support, frequency assignments, telemetry, command, and tracking mission responsibility.

  11. Shootin1

    DEFF Research Database (Denmark)

    Toriyama, Michinori; Shimada, Tadayuki; Kim, Ki Bum;

    2006-01-01

    Neurons have the remarkable ability to polarize even in symmetrical in vitro environments. Although recent studies have shown that asymmetric intracellular signals can induce neuronal polarization, it remains unclear how these polarized signals are organized without asymmetric cues. We describe a...... to the growth cones and diffused back to the soma; inhibiting this transport prevented its asymmetric accumulation in neurons. We propose that shootin1 is involved in the generation of internal asymmetric signals required for neuronal polarization....

  12. Mercury(1)

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    1.Mercury is the planet closest to the sun.It is thefastest moving planet.And it is the second smallestplanet in our solar system. 2.Mercury is very difficult to see.Its orbit isbetween us and the sun.So,we have to look toward thebright light of the sun to see it.The sunlight usuallyhides Mercury.When we can see it,it appears as a fuzzyball.

  13. Wetlands; 1 : 1 000 000

    International Nuclear Information System (INIS)

    The most valuable swamps and other hydrophilic associations represent wetlands. In the years 1991 - 2000, 261 specialists carried out their inventory. Apart from these localities another 1,050 locally important wetlands were identified while more than 500 wetlands were identified geographically, i.e. without characterisation of flora and fauna, which prevented their categorisation. The source material used for mapping of wetlands was provided by the Centre for Wetland Mapping of the Slovak Union of Nature and Landscape Conservationists in Prievidza. Mapping of wetlands in Slovakia continues and its main aim is to: (1) cartographically process the yet not investigated territories, for instance, the districts of Humenne, Zlate Moravce, and other; (2) explore fauna and flora of more than 500 geographically identified wetlands; (3) update the state of biota of internationally and nationally important wetlands; (4) involve more specialists in inventory of wetlands. (authors)

  14. 1-Benzylimidazolium hexafluorophosphate–1-benzylimidazole (1/1

    Directory of Open Access Journals (Sweden)

    Qing-Xiang Liu

    2008-02-01

    Full Text Available In the title compound, C10H11N2+·PF6−·C10H10N2, the H atom involved in protonation is disordered equally between the cation and the neutral molecule. The dihedral angle between the phenyl and imidazole rings is 82.6 (2°. In the crystal structure, there are head-to-tail π–π stacking interactions between imidazole rings; the interplanar separation is 3.295 (1 Å and the centroid–centroid separation is 3.448 (3 Å. In the centrosymmetric anion, two F atoms are disordered over two positions; the refined site-occupancy factors are 0.855 (11 and 0.145 (11.

  15. Methane dissociation on Pt(1 1 1), Ir(1 1 1) and PtIr(1 1 1) surface: A density functional theory study

    Energy Technology Data Exchange (ETDEWEB)

    Qi, Qiuhong; Wang, Xiujun, E-mail: xjwangcn@scut.edu.cn; Chen, Li; Li, Baitao

    2013-11-01

    A periodic density functional theory (DFT) was utilized to calculate the dissociation process of methane (CH{sub 4}) on Pt(1 1 1), Ir(1 1 1) and PtIr(1 1 1) surfaces. As compared to the adsorption energy, the most stable configurations of methane, methane dissociation species and co-adsorption of CH{sub x} (x = 0–3) with H were obtained. The kinetic results of the CH{sub 4} dissociation indicated that the dissociating of CH{sub 4} into CH{sub 3} and H is the rate-limiting step on the PtIr(1 1 1) and Ir(1 1 1) surfaces. CH was the most abundant species that was difficult to dehydrogenate into C and H. Particularly, the activation barrier for CH{sub 3} → CH{sub 2} + H and CH{sub 2} → CH + H on the Pt(1 1 1) surface is 3.5 and 1.4 times, respectively, higher than that on the PtIr(1 1 1) surface. According to the thermodynamics principles, the successive dehydrogenation of CH{sub 4} preferred to take place on the PtIr surface.

  16. CH{sub 4} dehydrogenation on Cu(1 1 1), Cu@Cu(1 1 1), Rh@Cu(1 1 1) and RhCu(1 1 1) surfaces: A comparison studies of catalytic activity

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Riguang; Duan, Tian [Key Laboratory of Coal Science and Technology of Ministry of Education and Shanxi Province, Taiyuan University of Technology, Taiyuan 030024, Shanxi (China); Ling, Lixia [Key Laboratory of Coal Science and Technology of Ministry of Education and Shanxi Province, Taiyuan University of Technology, Taiyuan 030024, Shanxi (China); Research Institute of Special Chemicals, Taiyuan University of Technology, Taiyuan 030024, Shanxi (China); Wang, Baojun, E-mail: wangbaojun@tyut.edu.cn [Key Laboratory of Coal Science and Technology of Ministry of Education and Shanxi Province, Taiyuan University of Technology, Taiyuan 030024, Shanxi (China)

    2015-06-30

    Highlights: • Adsorbed Rh atom on Cu catalyst exhibits better catalytic activity for CH{sub 4} dehydrogenation. • The adsorbed Rh atom is the reaction active center for CH{sub 4} dehydrogenation. • The morphology of Cu substrate has negligible effect on CH{sub 4} dehydrogenation. - Abstract: In the CVD growth of graphene, the reaction barriers of the dehydrogenation for hydrocarbon molecules directly decide the graphene CVD growth temperature. In this study, density functional theory method has been employed to comparatively probe into CH{sub 4} dehydrogenation on four types of Cu(1 1 1) surface, including the flat Cu(1 1 1) surface (labeled as Cu(1 1 1)) and the Cu(1 1 1) surface with one surface Cu atom substituted by one Rh atom (labeled as RhCu(1 1 1)), as well as the Cu(1 1 1) surface with one Cu or Rh adatom (labeled as Cu@Cu(1 1 1) and Rh@Cu(1 1 1), respectively). Our results show that the highest barrier of the whole CH{sub 4} dehydrogenation process is remarkably reduced from 448.7 and 418.4 kJ mol{sup −1} on the flat Cu(1 1 1) and Cu@Cu(1 1 1) surfaces to 258.9 kJ mol{sup −1} on RhCu(1 1 1) surface, and to 180.0 kJ mol{sup −1} on Rh@Cu(1 1 1) surface, indicating that the adsorbed or substituted Rh atom on Cu catalyst can exhibit better catalytic activity for CH{sub 4} complete dehydrogenation; meanwhile, since the differences for the highest barrier between Cu@Cu(1 1 1) and Cu(1 1 1) surfaces are smaller, the catalytic behaviors of Cu@Cu(1 1 1) surface are very close to the flat Cu(1 1 1) surface, suggesting that the morphology of Cu substrate does not obviously affect the dehydrogenation of CH{sub 4}, which accords with the reported experimental observations. As a result, the adsorbed or substituted Rh atom on Cu catalyst exhibit a better catalytic activity for CH{sub 4} dehydrogenation compared to the pure Cu catalyst, especially on Rh-adsorbed Cu catalyst, we can conclude that the potential of synthesizing high-quality graphene with the

  17. Theoretical study of NH3 decomposition on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces: A comparison with clean Pd (1 1 1) and Cu (1 1 1)

    Science.gov (United States)

    Jiang, Zhao; Qin, Pei; Fang, Tao

    2016-05-01

    The adsorption and successive dehydrogenation mechanisms of NH3 on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces (the Pd atoms substitution of the first and second layers of Cu (1 1 1) surfaces) have been systematically investigated by density functional theory (DFT) method with a periodic slab model. All possible adsorption configurations of relevant intermediates on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces are identified. It is revealed that the adsorption configurations and corresponding adsorption energies of adsorbates are slightly changed on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces. The adsorption energies of NHx(x = 0-3) species exhibit the following trend: NH3 energy path for the complete dehydrogenation of NH3 into adsorbed N and H is identified to explore the dehydrogenation mechanisms on different surfaces. The highest energy barrier and reaction energy on Pd-Cu (1 1 1) surface are greatly reduced to 1.56 and 0.99 eV, implying that the complete dehydrogenation of NH3 on Pd-Cu (1 1 1) surface is favorable both kinetically and thermodynamically, namely, the doped-Pd atoms in the first layer are the reaction active center. Compared to that on clean Pd (1 1 1) and Cu (1 1 1) surfaces, it is found that the synergistic effect exits in different layers of catalyst surfaces. The calculated results show that the layer-substituted Pd atoms on the surface of Cu catalysts exhibit a better catalytic activity for NH3 dehydrogenation compared to the clean Cu (1 1 1) surface.

  18. PSA analysis focused on Mochovce safety measure evaluation from operational safety point of view

    International Nuclear Information System (INIS)

    Mochovce NPP consists of four reaktor units of WWER 440/V213 type and it is located in the south-middle part of Slovakia. At present units 1 and 2 are in operation. As these units represent the second generation of WWER reactor design, additional safety measures were implemented to enhance operational and nuclear safety according to the recommendations of international audits and operational experience from other simular units (such as Dukovany and Bohunice). These requirements result into a number of safety measures grouped according to their purpose to achieve recent international requirements on nuclear and operational safety. The paper presents the bases used for specification of safety measures including their grouping into comprehensive tasks covering different areas of safety goals as well as structural organization of project management including participating companies and work performance. Results are also given regarding the contribution of selected safety measures to reduction of total core damage frequency. (authors)

  19. Main: SITE1SORPS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SITE1SORPS1 S000211 11-May-2006 (last modified) kehi Site 1 in the spinach (S.o.) rps1 promoter; S1...FSORPL21); S1 box=ATGGTA; Site 1; rps1; ribosomal protein; S1F; leaf; leaf-specific; repression; negative; spinach (Spinacia oleracea); TCATGGTAACAATT ... ...er; Related to GT elements; For a compilation of related GT elements and factors, see Villain et al. (1996); See S000215 (S1

  20. Main: 1FK1 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1FK1 トウモロコシ Corn Zea mays L. Nonspecific Lipid-Transfer Protein Precursor Zea Mays ...RGQGSGPSAGCCSGVRSLNNAARTTADRRAACNCLKNAAAGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN corn_1FK1.jpg ...

  1. Main: 1OM1 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1OM1 トウモロコシ Corn Zea mays L. Casein Kinase Ii, Alpha Chain Name=Ack2; Zea Mays Mole...ELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENSRTRA corn_1OM1.jpg ...

  2. Main: L1BOXATPDF1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available L1BOXATPDF1 S000386 05-November-2005 (last modified) kehi L1 box found in promoter ...of Arabidopsis thaliana (A.t.) PROTODERMAL FACTOR1 (PDF1) gene; Located between -134 and -127; Involved in L...ding motif (Wang et al., 2004); HDZip IV; See also S000371; PDF1; L1 box; L1 layer-specific expression; Shoo

  3. 26 CFR 1.936-1 - Elections.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Elections. 1.936-1 Section 1.936-1 Internal... TAXES Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning after December...

  4. Main: 1TQ1 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available ; AAM61332.1; -.|EMBL; BT000864; AAN38701.1; -.|PDB; 1TQ1; NMR; A=-.|InterPro; IPR001763; Rhodanese-like.|Pfam; PF00581; Rhodane...se; 1.|SMART; SM00450; RHOD; 1.|PROSITE; PS50206; RHODANESE_3

  5. Containment of 0 and 1 in 1(, )

    Indian Academy of Sciences (India)

    Mohsen Alimohammady

    2004-05-01

    Suppose 1(, ) is the space of all absolutely 1-summing operators between two Banach spaces and . We show that if has a copy of 0, then 1(, ) will have a copy of 0, and under some conditions if has a copy of 1 then 1(, ) would have a complemented copy of 1.

  6. 26 CFR 1.535-1 - Definition.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition. 1.535-1 Section 1.535-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.535-1 Definition. (a)...

  7. 26 CFR 1.801-1 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... TAXES Life Insurance Companies § 1.801-1 Definitions. (a) Life insurance company. The term life.... For the definition of an “insurance company”, see paragraph (b) of this section. In determining... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Definitions. 1.801-1 Section 1.801-1...

  8. 45 CFR 1216.1-1 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Purpose. 1216.1-1 Section 1216.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE NONDISPLACEMENT OF EMPLOYED WORKERS AND NONIMPAIRMENT OF CONTRACTS FOR SERVICE § 1216.1-1 Purpose. This...

  9. KINERJA KATALIS Ag/Al2O3 UNTUK REDUKSI NOx

    Directory of Open Access Journals (Sweden)

    Rakhman Sarwono

    2012-02-01

    Full Text Available NOx merupakan hasil samping dari suatu reaksi pembakaran. NOx merupakan gas yang beracun sangat berbahaya terhadap kesehatan manusia dan hewan bila terhirup pada waktu bernafas. Untuk mengurangi kadar NOx pada gas buang, banyak penelitian diarahkan pada reduksi NOx dengan katalis secara selektif dengan hidrokarbon dan oksigen berlebihan. Katalis yang digunakan adalah katalis alumina (Al2O3 yang didapat dari katalis komersial (AlO1-7 dan katalis hasil sintesa (ALOA. Katalis Ag/Al2O3 didapat dengan memasukkan logam Ag ke dalam alumina (Al2O3 dengan cara impregnasi dengan larutan perak nitrat. Katalis diuji aktifitasnya pada reaktor fixed bed yang diluarnya terdapat pemanas yang bisa diatur suhunya. Reaktan seperti gas NO, C2H4  dan oksigen dimasukkan kedalam reaktor dengan laju yang ditentukan. Hasil reaksi dianalisa dengan gas chromatography dan dicatat pada recorder, selanjutnya bisa ditentukan kuantitas dan prosentase konversinya. Katalis alumina  ALOA mempunyai kemampuan mereduksi NO dengan konversi  sekitar 40-45% gas NO menjadi N2. Loading logam perak (Ag kedalam Al2O3 sebesar 2-3% berat menambah daya reduksi NO menjadi sekitar 45-50% pada suhu 500oC. Pada umpan NO + C2H4  + O2  reaksi reduksi terjadi pada suhu 300oC, sedangkan pada umpan NO + C2H4   (tanpa oksigen reaksi reduksi baru terjadi pada suhu 450oC, dengan demikian adanya oksigen sangat berperan dalam proses reduksi NOx. Reaksi peruraian C2H4 menjadi COx berkebalikan dengan kinerja katalis pada proses reduksi NOx

  10. Main: CCA1ATLHCB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available CCA1ATLHCB1 S000149 10-May-1998 (last modified) kehi CCA1 binding site; CCA1 protei...n (myb-related transcription factor) interact with two imperfect repeats of AAMAATCT in Lhcb1*3 gene of Arab

  11. Reference: SITE1SORPS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SITE1SORPS1 Villain P, Clabault G, Mache R, Zhou DX S1F binding site is related to ...but different from the light-responsive GT-1 binding site and differentially represses the spinach rps1 prom

  12. 9 CFR 1.1 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  13. 1 CFR 3.1 - Information services.

    Science.gov (United States)

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  14. Põhja-Korea lubas taas jätta tuumaplaanid / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2007-01-01

    Pekingis toimunud kuuepoolsete desarmeerimiskõneluste tulemusena on Põhja-Korea nõus andma ülevaate riigi tuumarajatistest ning alustama nende likvideerimist. 14. juulil suleti Yongbyoni tuumakeskuse reaktor. Lisa: Tuumavaidlus

  15. Adamkus : EU might be willing to negotiate on postponing Ignalina reactor closure

    Index Scriptorium Estoniae

    2008-01-01

    President Valdas Adamkus teatas võimalusest, et EL alustab arutelu Ignalina tuumaelektrijaama sulgemise edasilükkamisest. Uue jaama valmimise aeg pole teada ning praegune reaktor on tänu rootslaste abile turvaline

  16. Main: ELRE1PCPAL1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ELRE1PCPAL1 S000306 10-Feb-2000 (last modified) seki One of two elicitor (ELRE) and... light response elements (LRE) found in the parsley (P.c.) phenylalanine ammonia-lyase (PAL-1) gene promoter

  17. Angle-resolved photoemission study of Ag(1 1 1)

    Science.gov (United States)

    Edamoto, K.; Miyazaki, E.; Shimokoshi, K.; Kato, H.

    1990-01-01

    The (1 1 1) face of Ag has been studied by angle-resolved photoemission spectroscopy utilizing synchrotron radiation as the excitation source (25 FIRO method. The peak positions thus determined are used to map the dispersion curves along the lang1 1 1rang (Γ-L) direction. The results show general agreement with calculated band structure, so far as the energy levels and symmetries are concerned. However, it is found that the density of state effect is dominant in the spectra obtained in the present photon energy region. The emission from the Ag 5s, p bands is observed to be broadened due to the indirect transition process.

  18. G18.95-1.1

    International Nuclear Information System (INIS)

    New radio continuum and spectral line observations of the Galactic radio source G18.95-1.1 are reported. The distance to G18.95-1.1 is 2 kpc as derived from HI-21 cm spectral line observations. These data also indicate an interaction with the interstellar medium. The radio continuum observations classify G18.95-1.1 as a composite supernova remnant

  19. Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.

    Science.gov (United States)

    Vachal, Petr; Toth, Leslie M; Hale, Jeffrey J; Yan, Lin; Mills, Sander G; Chrebet, Gary L; Koehane, Carol A; Hajdu, Richard; Milligan, James A; Rosenbach, Mark J; Mandala, Suzanne

    2006-07-15

    Novel series of sphingosine-1-phosphate (S1P) receptor agonists were developed through a systematic SAR aimed to achieve high selectivity for a single member of the S1P family of receptors, S1P1. The optimized structure represents a highly S1P1-selective and efficacious agonist: S1P1/S1P2, S1P1/S1P3, S1P1/S1P4>10,000-fold, S1P1/S1P5>600-fold, while EC50 (S1P1) <0.2 nM. In vivo experiments are consistent with S1P1 receptor agonism alone being sufficient for achieving desired lymphocyte-lowering effect.

  20. APE1/Ref-1: versatility in progress.

    Science.gov (United States)

    Jeon, Byeong Hwa; Irani, Kaikobad

    2009-03-01

    Apurinic/apyrimidinic endonuclease1/redox factor-1 (APE1/Ref-1) is a multifunctional protein involved in base excision DNA repair and in transcriptional regulation of gene expression. Over the past decade and a half, knowledge of the biological functions, interactions, mechanisms of action, and regulation of the protein APE1/Ref-1 has grown exponentially. The multifunctional nature of APE1/Ref-1 is uncovering and has been extensively studied in the cellular response against oxidative stress. Recent evidence shows a biological role of APE1/Ref-1 can be modulated by the different post-translational modification. Because of APE1/Ref-1 importance to genomic stability and cell survival, APE1/Ref-1 is focused as the leading therapeutic target molecule for the oxidative stress condition or pathologic conditions such as cancer. This forum, dedicated to APE1/Ref-1, provides ample testimony that even though we have learned a great deal about APE1/Ref-1 over the past 15-plus years, our knowledge still constitutes the tip of the iceberg when it comes to understanding this versatile protein.

  1. Development of an improved methodology for the determination of the neutron load of the pressure vessel steel of WWER-1000 type reactors. Final report; Entwicklung einer fortgeschrittenen Methodik zur Bestimmung der Neutronenbelastung des Druckbehaeltermaterials vom Reaktor des Typs WWER-1000. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Barz, H.U.; Boehmer, B.; Konheiser, J.; Stephan, I.

    1998-05-01

    The investigations, reported on here, are aimed at the theoretical and experimental determination of the neutron exposure of the VVER-1000 reactors Balakovo-3 and Rovno-3. The overall approach, partially developed and at least improved in the frame of this project, comprises the pure calculation part, the gamma spectrometric analysis of neutron activation detectors and the comparison of experimental and theoretical results using the spectrum adjustment procedure. The approach is not restricted to neutron embrittlement but can be applied to neutron fluence problems in general. (orig./GL) [Deutsch] In diesem Projekt wurden fuer die WWER-1000 Reaktoren Balakovo-3 und Rovno-3 die Parameter der Neutronenbelastung experimentell und theoretisch bestimmt. Der vorliegende Bericht beschreibt das methodische Vorgehen, welches aus dem reinen Berechnungsteil, der gammaspektrometrischen Analyse der Ativierungsdetektoren und dem Vergleich der gemessenen und berechneten Werte einschliesslich der Spektrumsjustierung besteht. Dieses Instrumentarium, welches allgemein bei der Bestimmung der Neutronenfluenz anwendbar ist, wurde im Projektzeitraum weiter verbessert. (orig./GL)

  2. Katalytische Abluftreinigung : verfahrenstechnische Aufgaben und neue Lösungen

    OpenAIRE

    Eigenberger, Gerhart; Nieken, Ulrich

    1991-01-01

    Neue Verfahren der katalytischen Abluftreinigung mit im Reaktor integriertem regenerativem Wärmeaustausch erlauben die autotherme Abluftreinigung bis zu Schadstoffkonzentrationen entsprechend einer adiabaten Temperaturerhöhung von weniger als 20°C. Bei höheren Konzentrationen erlaubt ein Mittenabzug die nahezu vollständige Auskopplung der Verbrennungswärme auf dem höchsten im Reaktor vorliegenden Temperaturniveau. Infolge der Rückkopplung durch den integrierten Wärmeaustausch besitzt der Ablu...

  3. Kinetische Untersuchungen zur Methanol-Dampfreformierung am PdZn/ZnO-Katalysatorsystem

    OpenAIRE

    Kölbl, Andreas

    2004-01-01

    In dieser Arbeit wird eine neuartige Strömungsapparatur mit Mikrostrukturreaktor vorgestellt. Diese erlaubt katalytische Experimente in einem großen Druckbereich. Verschiedene Dosierungskonzepte zur Realisierung kleiner Reaktandenpartialdrücke im Reaktor werden diskutiert. Es wird gezeigt und experimentell verifiziert, dass durch die Teilung des generierten Eduktstroms und eine Teildosierung durch Kapillaren in den Reaktor im Vergleich zu klassischen Methoden wie der zusätzlichen Dosierung vo...

  4. Superconformal SU(1, 1|n) mechanics

    Science.gov (United States)

    Galajinsky, Anton; Lechtenfeld, Olaf

    2016-09-01

    Recent years have seen an upsurge of interest in dynamical realizations of the superconformal group SU(1, 1|2) in mechanics. Remarking that SU(1, 1|2) is a particular member of a chain of supergroups SU(1, 1| n) parametrized by an integer n, here we begin a systematic study of SU(1, 1| n) multi-particle mechanics. A representation of the superconformal algebra su(1, 1| n) is constructed on the phase space spanned by m copies of the (1, 2 n, 2 n-1) supermultiplet. We show that the dynamics is governed by two prepotentials V and F, and the Witten-Dijkgraaf-Verlinde-Verlinde equation for F shows up as a consequence of a more general fourth-order equation. All solutions to the latter in terms of root systems reveal decoupled models only. An extension of the dynamical content of the (1, 2 n, 2 n-1) supermultiplet by angular variables in a way similar to the SU(1, 1|2) case is problematic.

  5. 7 CFR 301.1-1 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... Animal and Plant Health Inspection Service of the United States Department of Agriculture. Biological... 7 Agriculture 5 2010-01-01 2010-01-01 false Definitions. 301.1-1 Section 301.1-1 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

  6. Superconformal SU(1,1|n) mechanics

    CERN Document Server

    Galajinsky, Anton

    2016-01-01

    Recent years have seen an upsurge of interest in dynamical realizations of the superconformal group SU(1,1|2) in mechanics. Remarking that SU(1,1|2) is a particular member of a chain of supergroups SU(1,1|n) parametrized by an integer n, here we begin a systematic study of SU(1,1|n) multi-particle mechanics. A representation of the superconformal algebra su(1,1|n) is constructed on the phase space spanned by m copies of the (1,2n,2n-1) supermultiplet. We show that the dynamics is governed by two prepotentials V and F, and the Witten-Dijkgraaf-Verlinde-Verlinde equation for F shows up as a consequence of a more general fourth-order equation. All solutions to the latter in terms of root systems reveal decoupled models only. An extension of the dynamical content of the (1,2n,2n-1) supermultiplet by angular variables in a way similar to the SU(1,1|2) case is problematic.

  7. The chemistry of 1,1-dithiolates

    DEFF Research Database (Denmark)

    1970-01-01

    The reaction of dipotassium 2-nitroethylene-1,1-dithiolate (III) with α-halogeno aldehydes or ketones leads to derivatives of 3-nitro-thiophene-2-thiols. These reactions proceed by an acid catalyzed cyclization of the initially formed 1-(acylmethylthio)-2-nitroethylene-1-thiolates (IV). The infra...

  8. Efek Durasi Pencahayaan Pada Sistem HRAR Untuk Menurunkan Kandungan Minyak Solar Dalam Air Limbah

    Directory of Open Access Journals (Sweden)

    Dian Puspitasari

    2014-09-01

    Full Text Available Kandungan minyak di dalam air limbah industri perminyakan umumnya bersifat toksik terhadap mikroorganisme dan mengganggu proses pengolahan secara biologis. Sistem HRAR diperkirakan dapat mengatasi hambatan tersebut melalui proses fotosintesis untuk menghasilkan oksigen yang dibutuhkan mikroorganisme dalam mendegradasi senyawa hidrokarbon. Penelitian ini bertujuan mengkaji pengaruh perpanjangan waktu pencahayaan pada kemampuan HRAR dalam menurunkan kandungan minyak di dalam limbah. Variabel yang digunakan pada penelitian ini adalah variasi durasi pencahayaan dan variasi penambahan volume minyak solar yang ditambahkan ke dalam reaktor. Variasi durasi pencahayaan yang digunakan adalah pencahayaan selama 12 jam dan pencahayaan selama 24 jam. Sedangkan penambahan volume minyak solar ke dalam masing-masing reaktor adalah sebesar 346 ppm, 519 ppm dan 692 ppm. Hasil yang didapatkan dari penelitian ini adalah durasi pencahayaan selama 12 jam memiliki efek yang lebih baik terhadap penurunan konsentrasi minyak dibandingkan pencahayaan selama 24 jam. Hal ini dapat terlihat dari baiknya pertumbuhan alga dan bakteri di dalam reaktor serta tingginya penurunan konsentrasi minyak solar di dalamnya. Penurunan konsentrasi minyak solar terbaik terdapat pada reaktor dengan penambahan minyak solar sebesar 346 ppm. Pada reaktor dengan durasi pencahayaan selama 12 jam terjadi penurunan konsentrasi minyak sebesar 78,4%. Sedangkan penurunan kandungan minyak solar pada reaktor dengan durasi pencahayaan selama 24 jam adalah sebesar 73,9%.

  9. Technetium (tin) ethane-1-hydroxy-1, 1-diphosphonate complexes

    International Nuclear Information System (INIS)

    The aim of this thesis is to establish the experimental conditions for the optimal preparation of the sup(99m)Tc(Sn)EHDP bone scanning agent. The pH and the concentrations of EHDP (ethane-1-hydroxy-1,1-disodium diphosphonate) and of Sn(II) may affect the yield and the biodistribution of the radiopharmacon. The investigation of the influence of these parameters is the subject of this investigation. (Auth.)

  10. XBZ1, XBJ1 Intelligent Transformer Substation

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    After conducting in-depth studies on and making improvements to the operational conditions of the current transformer substation, the advanced technology of the XBZ1 intelligent transformer substation and XBJ1 pre-installed transformer

  11. The chemistry of 1,1-dithiolates

    DEFF Research Database (Denmark)

    1972-01-01

    A series of thieno[3,2-e]-3,4-dihydro-1,2,3-triazin-4-ones (V) and thieno[3,4-e]-3,4-dihydro-1,2,3-triazin-4-ones (VI) were prepared by diazotation of 3-aminothiophene-2-carboxamides (III) and 4-amino-thiophene-3-carboxamides (IV), respectively, both obtained by cyclization of 2-cyanoethylene-1,1...

  12. Main: GARE1OSREP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available GARE1OSREP1 S000419 28-November-2004 (last modified) kehi Gibberellin-responsive element (GARE...) found in the promoter region of a cystein proteinase (REP-1) gene in rice; See S000020; aleurone; GARE; gibberellin; seed; Oryza sativa (rice) TAACAGA ...

  13. 26 CFR 1.316-1 - Dividends.

    Science.gov (United States)

    2010-04-01

    ... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Definitions; Constructive Ownership of Stock § 1.316-1 Dividends. (a)(1) The term dividend for the... income tax law, was under the applicable law a personal holding company, the term dividend, in...

  14. Reference: MNF1ZMPPC1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available MNF1ZMPPC1 Morishima A Identification of preferred binding sites of a light-inducib...le DNA-binding factor (MNF1) within 5'-upstream sequence of C4-type phosphoenolpyruvate carboxylase gene in maize Plant Mol Biol 38:633-646 (1998) PubMed: 9747808; ...

  15. Cuba vs H1N1 Influenza

    Directory of Open Access Journals (Sweden)

    Gail Reed

    2011-04-01

    Full Text Available El Comité Editorial de MediSur agradece a Gail Reed, editora de Medicc Review la autorización expresa, para reproducir el artículo titulado “Cuba vs H1N1 Influenza”. Este trabajo resume el esfuerzo realizado por todos los organismos en Cuba y en especial el Ministerio de Salud Pública en la lucha para disminuir los efectos de la influenza H1N1 en la población. El artículo original se puede encontrar en: Reed G. Faceoff: Cuba vs H1N1 Influenza. MEDICC Review. 2010; 12(1:6-12. Disponible en: http://www.medicc.org/mediccreview/index.php?issue=11

  16. Cuba vs H1N1 Influenza

    Directory of Open Access Journals (Sweden)

    Gail Reed

    2011-04-01

    Full Text Available El Comité Editorial de MediSur agradece a Gail Reed, editora de Medicc Review la autorización expresa, para reproducir el artículo titulado “Cuba vs H1N1 Influenza”. Este trabajo resume el esfuerzo realizado por todos los organismos en Cuba y en especial el Ministerio de Salud Pública en la lucha para disminuir los efectos de la influenza H1N1 en la población. El artículo original se puede encontrar en: Reed G. Faceoff: Cuba vs H1N1 Influenza. MEDICC Review. 2010; 12(1:6-12. Disponible en: http://www.medicc.org/mediccreview/index.php?issue=11

  17. Breast Cancer Susceptibility Gene1 (BRCA1

    Directory of Open Access Journals (Sweden)

    Wasiksiri, S.

    2002-07-01

    Full Text Available Breast Cancer Susceptibility Gene1 (BRCA1 is a tumor suppressor gene for breast and ovarian cancers. The gene locates at chromosome 17q21 and encodes for 1863 amino acids protein. It is believed that BRCA1 protein is involved in many functions such as DNA repair, centrosome replication, cell cycle checkpoint and replication of other genes. More than 800 mutations have been found in the population with an increased risk of cancer incidence in their families. Germ-line mutation of BRCA1 accounts for 5-10 percent of all breast cancer cases. Epigenetic modifications also reduce the function of normal BRCA1 gene. Several methods are used for laboratory diagnosis of cancer-related mutations. The development of breast cancer in carriers at risk with BRCA1 mutations may be prevented by suitable prevention plans such as breast cancer screening, ovarian cancer screening, surgery and cancer chemotherapy.

  18. VANDAL user guide. V. 1.1

    International Nuclear Information System (INIS)

    This document forms Volume 1.1 of the VANDAL User Guide and is intended to provide all the information necessary to define and run a case study. Information is given on the data to be specified, on the structure of the input data files and on how to execute the system. There are three related volumes to this, they are: Volume 1.2 - Input and Execution Appendices; Volume 2.1 - Ouput and Error Messages; and Volume 2.2 - PRA Output Analysis. (author)

  19. Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.

    Science.gov (United States)

    Chen, M; Qu, B X; Chen, X L; Hu, H H; Jiang, H D; Yu, L S; Zhou, Q; Zeng, S

    2016-06-01

    A transgenic cell line stably expressing the human organic anion transporting polypeptide (OATP1B1) was established. Human Embryonic Kidney 293 (HEK293) cell line stably expressing OATP1B1*1a sequence was amplified through PCR with the extracted total RNA as templates from human liver, then subcloned into the plasmid pMD19-T and verified by sequencing. OATP1B1*1b/OATP1B1*15 mutant sequences were obtained by site-directed mutation PCR with pMD19-T/ OATP1B1*1a as templates. The plasmids pcDNA3.1(+)/OATP1B1*1a, *1b and *15 were constructed and transfected into HEK293 cell line using Lipofectamine 2000 transfection reagent. Several stable transfected clones were obtained after selection with G418. Using rosuvastatin as a probe substrate of OATP1B1, the intracellular rosuvastatin accumulation in HEK293 and HEK-OATP1B1*1a, *1b and *15 monoclone cells were validated by a ultra-performance liquid chromatography-tandem mass spectrometry. OATP1B1 mRNA and protein expression were detected by RT-PCR and Western blot, respectively. The results from RT-PCR, rosuvastatin uptake and Western blot assay indicated that human OATP1B1 was highly expressed in transfected cells compared with controls. The HEK-293 cell lines stably expressing human OATP1B1-wild and variant (HEK-OATP1B1, *1b and *15) are potential models to study drug transport in vitro. PMID:27455553

  20. Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.

    Science.gov (United States)

    Chen, M; Qu, B X; Chen, X L; Hu, H H; Jiang, H D; Yu, L S; Zhou, Q; Zeng, S

    2016-06-01

    A transgenic cell line stably expressing the human organic anion transporting polypeptide (OATP1B1) was established. Human Embryonic Kidney 293 (HEK293) cell line stably expressing OATP1B1*1a sequence was amplified through PCR with the extracted total RNA as templates from human liver, then subcloned into the plasmid pMD19-T and verified by sequencing. OATP1B1*1b/OATP1B1*15 mutant sequences were obtained by site-directed mutation PCR with pMD19-T/ OATP1B1*1a as templates. The plasmids pcDNA3.1(+)/OATP1B1*1a, *1b and *15 were constructed and transfected into HEK293 cell line using Lipofectamine 2000 transfection reagent. Several stable transfected clones were obtained after selection with G418. Using rosuvastatin as a probe substrate of OATP1B1, the intracellular rosuvastatin accumulation in HEK293 and HEK-OATP1B1*1a, *1b and *15 monoclone cells were validated by a ultra-performance liquid chromatography-tandem mass spectrometry. OATP1B1 mRNA and protein expression were detected by RT-PCR and Western blot, respectively. The results from RT-PCR, rosuvastatin uptake and Western blot assay indicated that human OATP1B1 was highly expressed in transfected cells compared with controls. The HEK-293 cell lines stably expressing human OATP1B1-wild and variant (HEK-OATP1B1, *1b and *15) are potential models to study drug transport in vitro.

  1. Growth of monocrystalline Cu(1 1 1) films on MgO(1 1 1) by pulsed laser deposition

    Energy Technology Data Exchange (ETDEWEB)

    Aweke, F.; Antoni, F. [ICube, Université de Strasbourg-CNRS(UMR 7357), 23 rue du Loess, 67037 Strasbourg (France); Hulik, J. [ICube, Université de Strasbourg-CNRS(UMR 7357), 23 rue du Loess, 67037 Strasbourg (France); Comenius University in Bratislava, Faculty of Mathematics, Physics and Informatics, Department of Experimental Physics, Mlynská dolina F2, 842 48 Bratislava (Slovakia); Morvan, G. [LHyGeS – Laboratoire d’Hydrologie et de Géochimie de Strasbourg, Université de Strasbourg-CNRS-EOST, 1 rue Blessing, 67084 Strasbourg (France); Speisser, C. [ICube, Université de Strasbourg-CNRS(UMR 7357), 23 rue du Loess, 67037 Strasbourg (France); Veis, P. [Comenius University in Bratislava, Faculty of Mathematics, Physics and Informatics, Department of Experimental Physics, Mlynská dolina F2, 842 48 Bratislava (Slovakia); Le Normand, F., E-mail: francois.le-normand@unistra.fr [ICube, Université de Strasbourg-CNRS(UMR 7357), 23 rue du Loess, 67037 Strasbourg (France)

    2015-05-01

    Copper (Cu) films with a minimal thickness of 300 nm were grown on MgO(1 1 1) substrates in high vacuum by pulsed laser deposition (PLD) at various temperatures to achieve a single crystal Cu film with flat terraces without grain boundaries. We investigated the effect of the substrate temperature, the pulse repetition rate, the deposition time and the laser fluence. A temperature threshold is observed above which the growth mode is changed from a uniform flat mode to a three dimensional mode. A combined process involving a germination step at moderate temperature followed by a growth step at higher temperature yields a 450 nm almost continuous film.

  2. Antiviral Prophylaxis and H1N1

    Centers for Disease Control (CDC) Podcasts

    2011-07-14

    Dr. Richard Pebody, a consultant epidemiologist at the Health Protection Agency in London, UK, discusses the use of antiviral post-exposure prophylaxis and pandemic H1N1.  Created: 7/14/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 7/18/2011.

  3. Expect Surprises with 1-to-1 Laptops

    Science.gov (United States)

    Tusch, Erich G.

    2012-01-01

    In 2004, prior to the launch of their 1-to-1 laptop program, the superintendent expressed some anxiety about the prospect of radically changing teaching and learning by issuing a laptop computer to every student and teacher. Although the concept was exciting, it carried big risks and would take time and thorough planning to execute well. Even with…

  4. Ciencias 1. (Science 1). [Student's Workbook].

    Science.gov (United States)

    Raposo, Lucilia

    Ciencias 1 is the first in a series of science books designed for elementary Portuguese-speaking students. The book contains five sections divided into 43 lessons. The five sections are (1) Matter, (2) The Human Body, (3) Weather, (4) Solids, Liquids, and Gases, and (5) Living Things. Pictorial presentations and picture exercises are included for…

  5. General Relativity in (1 + 1) Dimensions

    Science.gov (United States)

    Boozer, A. D.

    2008-01-01

    We describe a theory of gravity in (1 + 1) dimensions that can be thought of as a toy model of general relativity. The theory should be a useful pedagogical tool, because it is mathematically much simpler than general relativity but shares much of the same conceptual structure; in particular, it gives a simple illustration of how gravity arises…

  6. Main: BOXCPSAS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available BOXCPSAS1 S000226 10-May-1998 (last modified) kehi Box C in pea (P.s.) asparagine synthetase (AS1...) gene; Found at -45; AS1 is negatively regulated by light; Box C binds with nuclear proteins,... which was competed by a putative repressor element RE1 (see S000195); BOX C; AS; AS1; pea (Pisum sativum) CTCCCAC ...

  7. Mammalian CD1 and MR1 genes.

    Science.gov (United States)

    Reinink, Peter; Van Rhijn, Ildiko

    2016-08-01

    All higher vertebrates share the fundamental components of the adaptive immune system: the B cell receptor, the T cell receptor, and classical MHC proteins. At a more detailed level, their immune systems vary considerably, especially with respect to the non-polymorphic MHC class I-like proteins. In mammals, the CD1 family of lipid-presenting proteins is encoded by clusters of genes of widely divergent sizes and compositions. Another MHC class I-like protein, MR1, is typically encoded by a single gene that is highly conserved among species. Based on mammalian genomes and the available data on cellular expression profiles and protein structure, we review MR1 genes and families of CD1 genes in modern mammals from a genetic and functional perspective. Understanding the CD1 and MR1 systems across animal species provides insights into the specialized functions of the five types of CD1 proteins and facilitates careful consideration of animal models for human diseases in which immune responses to lipids and bacterial metabolites play a role. PMID:27470004

  8. Main: AMMORESIVDCRNIA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AMMORESIVDCRNIA1 S000375 31-Jul-2001 (last modified) uchi Motif (IVD) found in the Chlamydomonas (C.R.) Nia...1 gene promoter; Located between -51 and -42; Involved in Nia1 transcription repress

  9. Reference: EECCRCAH1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available EECCRCAH1 Yoshioka S, Taniguchi F, Miura K, Inoue T, Yamano T, Fukuzawa H. The nove...l Myb transcription factor LCR1 regulates the CO2-responsive gene Cah1, encoding a periplasmic carbonic anhy

  10. Conductors and Newforms for (1,1)

    Indian Academy of Sciences (India)

    Joshua Lansky; A Raghuram

    2004-11-01

    Let be a non-Archimedean local field whose residue characteristic is odd. In this paper we develop a theory of newforms for (1,1)(), building on previous work on $SL_2(F)$. This theory is analogous to the results of Casselman for $GL_2(F)$ and Jacquet, Piatetski-Shapiro, and Shalika for $GL_n(F)$. To a representation π of (1,1)(), we attach an integer () called the conductor of , which depends only on the -packet containing . A newform is a vector in which is essentially fixed by a congruence subgroup of level ()$. We show that our newforms are always test vectors for some standard Whittaker functionals, and, in doing so, we give various explicit formulae for newforms.

  11. G1SST, 1km blended SST

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A daily, global Sea Surface Temperature (SST) data set is produced at 1-km (also known as ultra-high resolution) by the JPL ROMS (Regional Ocean Modeling System)...

  12. 1-Benzyl-1H-benzotriazole 3-oxide–1-hydroxy-1H-benzotriazole (1/1

    Directory of Open Access Journals (Sweden)

    P. Selvarathy Grace

    2012-08-01

    Full Text Available In the title compound, C6H5N3O·C13H11N3O, the benzotriazole ring system in the 1-benzyl-1H-benzotriazole 3-oxide (A molecule is close to being planar (r.m.s. deviation = 0.011 Å; its mean plane forms a dihedral angle of 67.56 (7° with that of the attached phenyl ring. The benzotriazole ring system in the 1-hydroxybenzotriazole (B molecule is also close to being planar (r.m.s. deviation = 0.010 Å. In the crystal, weak C—H...O and C—H...π interactions are present. The A and B molecules are linked by an O—H...N hydrogen bond.

  13. SPARK Version 1.1 user manual

    International Nuclear Information System (INIS)

    This manual describes the input required to use Version 1.1 of the SPARK computer code. SPARK 1.1 is a library of FORTRAN main programs and subprograms designed to calculate eddy currents on conducting surfaces where current flow is assumed zero in the direction normal to the surface. Surfaces are modeled with triangular and/or quadrilateral elements. Lorentz forces produced by the interaction of eddy currents with background magnetic fields can be output at element nodes in a form compatible with most structural analysis codes. In addition, magnetic fields due to eddy currents can be determined at points off the surface. Version 1.1 features eddy current streamline plotting with optional hidden-surface-removal graphics and topological enhancements that allow essentially any orientable surface to be modeled. SPARK also has extensive symmetry specification options. In order to make the manual as self-contained as possible, six appendices are included that present summaries of the symmetry options, topological options, coil options and code algorithms, with input and output examples. An edition of SPARK 1.1 is available on the Cray computers at the National Magnetic Fusion Energy Computer Center at Livermore, California. Another more generic edition is operational on the VAX computers at the Princeton Plasma Physics Laboratory and is available on magnetic tape by request. The generic edition requires either the GKS or PLOT10 graphics package and the IMSL or NAG mathematical package. Requests from outside the United States will be subject to applicable federal regulations regarding dissemination of computer programs. 22 refs

  14. SPARK Version 1. 1 user manual

    Energy Technology Data Exchange (ETDEWEB)

    Weissenburger, D.W.

    1988-01-01

    This manual describes the input required to use Version 1.1 of the SPARK computer code. SPARK 1.1 is a library of FORTRAN main programs and subprograms designed to calculate eddy currents on conducting surfaces where current flow is assumed zero in the direction normal to the surface. Surfaces are modeled with triangular and/or quadrilateral elements. Lorentz forces produced by the interaction of eddy currents with background magnetic fields can be output at element nodes in a form compatible with most structural analysis codes. In addition, magnetic fields due to eddy currents can be determined at points off the surface. Version 1.1 features eddy current streamline plotting with optional hidden-surface-removal graphics and topological enhancements that allow essentially any orientable surface to be modeled. SPARK also has extensive symmetry specification options. In order to make the manual as self-contained as possible, six appendices are included that present summaries of the symmetry options, topological options, coil options and code algorithms, with input and output examples. An edition of SPARK 1.1 is available on the Cray computers at the National Magnetic Fusion Energy Computer Center at Livermore, California. Another more generic edition is operational on the VAX computers at the Princeton Plasma Physics Laboratory and is available on magnetic tape by request. The generic edition requires either the GKS or PLOT10 graphics package and the IMSL or NAG mathematical package. Requests from outside the United States will be subject to applicable federal regulations regarding dissemination of computer programs. 22 refs.

  15. Fluconazole–malonic acid (1/1

    Directory of Open Access Journals (Sweden)

    Nina Lah

    2013-03-01

    Full Text Available Co-crystallizaton of the antifungal drug fluconazole [2-(2,4-difluorophenyl-1,3-bis(1H-1,2,4-triazol-1-ylpropan-2-ol] with malonic acid in acetonitrile solution resulted in the formation of the title 1:1 co-crystal, C13H12F2N6O·C3H4O4. The geometry around the central fluconazole atom is distorted tetrahedral. The dihedral angles between the triazole rings and the fluorinated phenyl ring are 30.64 (7 and 61.91 (5°. In the crystal, the basic packing motif may be envisioned as a cyclic aggregate formed of two fluconazole molecules linked by two malonic acid molecules through O—H...N and O—H...O hydrogen bonds. Such aggregates are further connected into (001 layers by further O—H...N hydrogen bonds. The structure also features weak non-classical C—H...O and C—H...N interactions.

  16. Main: BOXBPSAS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available BOXBPSAS1 S000225 17-May-1998 (last modified) kehi Box B in pea (P.s.) asparagine synthetase (AS1...) gene; Found at -61; AS1 is negatively regulated by light; Box B binds with nuclear proteins; BOX B; AS; AS1

  17. Main: SPHZMC1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SPHZMC1 S000293 16-Feb-2001 (last modified) seki Sph element found in the maize (Z.m.) C1 gene promoter; Loc...ated between -142 and -132; Essential for VP1 activation; See S000154, S000294; VP1

  18. Main: ZDNAFORMINGATCAB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ZDNAFORMINGATCAB1 S000321 13-August-2005 (last modified) kehi Z-DNA-forming sequenc...t redundantly to induce Z-box containing promoters in white light; cab1; light; Z-DNA; leaf; shoot; HY5; COP1; LRE; Z-box; ZBF1; Z-box binding factor; Arabidopsis thaliana ATACGTGT ...

  19. Survey of ortho-H2D+ (1(1,0)-1(1,1)) in dense cloud cores

    NARCIS (Netherlands)

    Caselli, P.; Vastel, C.; Ceccarelli, C.; van der Tak, F. F. S.; Crapsi, A.; Bacmann, A.

    2008-01-01

    Aims. We present a survey of the ortho-H2D+ (1(1,0)-1(1,1)) line toward a sample of 10 starless cores and 6 protostellar cores, carried out at the Caltech Submillimeter Observatory. The high diagnostic power of this line is revealed for the study of the chemistry, and the evolutionary and dynamical

  20. 1.1.Physical method of diganosis.

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930209 Glinical and radiological diagnosis ofrenal osteodystrophy.CHEN Zhigang (陈志刚),et al.Dept Radiol,1st Affili Hosp,XianMed Univ,710061.Chin J Radiol 1992;26(1):726—729.The authors reported the radiological findingsin 42 cases of renal osteodystrophy as comparedwith 103 cases of chronic renal failure withoutbone changes.The results showed that renalosteodystrophy was closely related to age,sexand duration of renopathy (P<0.05).The au-thors suggested that osteosclerosis was a char-

  1. 1-Phenyl-3-(pyren-1-ylprop-2-en-1-one

    Directory of Open Access Journals (Sweden)

    Jiannian Yao

    2008-03-01

    Full Text Available The title compound, C25H16O, was prepared by the condensation reaction of pyrene-1-carbaldehyde and acetophenone in ethanol solution at room temperature. The phenyl ring forms a dihedral angle of 39.10 (11° with the pyrene ring system. In the crystal structure, adjacent pyrene ring systems are linked by aromatic π–π stacking interactions, with a perpendicular interplanar distance of 3.267 (6 Å and a centroid–centroid offset of 2.946 (7 Å.

  2. 1.1 Physical method of diagnosis

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920207 CT findings of dissecting aorticaneurysm(analysis of 24 cases).CHENJianhun (陈剑魂),et al.Dept Radiol,1st Hosp,Zhongshan Med Univ.Chin J Radiol 1991;25(6):348-350.CT findings of 24 cases with dissecting aortic

  3. Main: 1XQ1 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available cs (Cesg) Center For Eukaryotic Structural Genomics X-Ray Structure Of Putative T...E; PS00061; ADH_SHORT; 1. X-Ray Diffraction, Resolution: 2.10 Angstrom, R-Factor: 0.255, R-Free: 0.316 Lengt

  4. Sphingosine 1-Phosphate Receptor 1 (S1P1) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P1 Antagonist

    OpenAIRE

    Cahalan, Stuart M.; Gonzalez-Cabrera, Pedro J.; Nguyen, Nhan; Guerrero, Miguel; Cisar, Elizabeth A. George; Leaf, Nora B.; Brown, Steven J.; Roberts, Edward; Rosen, Hugh

    2013-01-01

    Sphingosine 1-phosphate receptor 1 (S1P1) is a G protein–coupled receptor that is critical for proper lymphocyte development and recirculation. Agonists to S1P1 are currently in use clinically for the treatment of multiple sclerosis, and these drugs may act on both S1P1 expressed on lymphocytes and S1P1 expressed within the central nervous system. Agonists to S1P1 and deficiency in S1P1 both cause lymphocyte sequestration in the lymph nodes. In the present study, we show that S1P1 antagonism ...

  5. Data of evolutionary structure change: 1CERQ-1GD1O [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CERQ-1GD1O 1CER 1GD1 Q O -MKVGINGFGRIGRQVFRILHSRG-VEVALINDLTDNKT...> VAL CA 439 ALA CA 385 LEU CA 456 1GD...1 O 1GD1O VAL CA 371 LYS CA 388 VAL CA 474 1GD...1 O 1GD1O TMVIDGKMVKV

  6. Main: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ory Sequence) found in maize and Arabidopsis ferritin genes (Fer1); IDRS is responsible for transcriptional ...IDRSZMFER1 S000445 04-August-2006 (last modified) kehi IDRS (Iron-Dependent Regulat...repression of ZmFer1 gene under low iron supply conditions; S=C/G; K=G/T; IDRS is not involved in the Fe-reg...ulated expression of the AtAPX1 gene (Fourcroy et al., 2004); iron; ferritin; APX1; AtFer1; Fer; Zea mays (maize); Arabidopsis thaliana; CACGAGSCCKCCAC ...

  7. Annual report 2002. 1.1.-21.1.2002

    International Nuclear Information System (INIS)

    In this Annual report of the Slovak Electric, plc (Slovenske elektrarne, a.s.) the results of operation in 2002 for the period from January 1 to January 21 are presented. It is unusual for a year to be considered as a matter of a few days, however, this is the case given the events at Slovak Electric, joint stock company which as of 21. 1. 2002 was dissolved and from which three new joint stock companies were established. Further proof of this is the annual report for 2002, which details the economic performance of the company during these 21 days, and the quantity of electricity and heat it generated and supplied to consumers. I am pleased to be able to state that this period of far-reaching changes during which the division of Slovak Electric, joint stock company into the new Slovak Electric, joint stock company, Slovak Electricity Transmission System, joint stock company and Heat Plant Kosice, joint stock company took place, did not cause any problems for Slovak consumers of electricity and heat. During the mentioned 21 January days of 2002, the sources of Slovak Electric generated 836,751 MWh of electricity, which represents 107 percent of the planned generation. The net profit for this period was 742,920 thousand crowns, the main influence being, of course, its short duration. As our economists have confirmed, the most important fact with a significant impact on net profit can be considered to be the amount of deferred taxes, which totalled 1,026,789 thou. Sk. With respect to the dissolution of the company, the company will apply 50 % tax depreciation from annual depreciation, which will, however, be reflected in the results of the newly established company - SE, a.s., as in the subsequent 344 day period its tax deductible depreciation will fall. It is clear that in the forthcoming period, in addition to this, many financial issues remain to be resolved by the management connected with the new form of the business, price, and management relationships within

  8. Main: ACGTROOT1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ture and ABA; root; ACGT; G box; G-box; ABRE motif; bZIP binding enhancement; cold tolerance; COR; SGBF-1; SCOF-1; tobacco (Nicotiana tabacum); soybean (Glycine max) GCCACGTGGC ...

  9. Reference: EECCRCAH1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available EECCRCAH1 Kucho K, Yoshioka S, Taniguchi F, Ohyama K, Fukuzawa H. Cis-acting elemen...ts and DNA-binding proteins involved in CO2-responsive transcriptional activation of Cah1 encoding a periplasmic ca

  10. Vitamin B1

    Science.gov (United States)

    ... Prize Alfred Nobel's Life and Work Teachers' Questionnaire Vitamin B1 - About The Chicken Farm educational game and ... the game window. Reading: "Christian Eijkman, Beriberi and Vitamin B1" - Who was Eijkman and why did he ...

  11. A1C test

    Science.gov (United States)

    HbA1C test; Glycated hemoglobin test; Glycosylated hemoglobin test; Hemoglobin glycosylated test; Glycohemoglobin test ... have recently eaten does not affect the A1C test, so you do not need to fast to ...

  12. Interferon Alfacon-1 Injection

    Science.gov (United States)

    Interferon alfacon-1 is no longer available in the United States. If you are currently taking this ... switching to another treatment.Your doctor has ordered interferon alfacon-1 to help treat your hepatitis C ...

  13. Reference: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available IDRSZMFER1 Arnaud N, Murgia I, Boucherez J, Briat JF, Cellier F, Gaymard F. An iron...-induced nitric oxide burst precedes ubiquitin-dependent protein degradation for arabidospsis atfer1 ferritin gene expre

  14. Reference: SRENTTTO1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SRENTTTO1 Takeda S, Sugimoto K, Otsuki H, Hirochika H A 13-bp cis-regulatory elemen...t in the LTR promoter of the tobacco retrotransposon Tto1 is involved in responsiveness to tissue culture, w

  15. Main: GBOXSORBCS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available .) RBCS-1 gene promoter; Located between -219 and -212; G-box trimer confers relatively high level expression in roots; RBCS-1; G-box; root; spinach (Spinacia oleracea) TCCACGTGGT ...

  16. Main: CGTGTSPHZMC1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available Z.m.) C1 gene promoter; Located between -147 to -132; Containing Sph element; Required for ABA responsivenes...CGTGTSPHZMC1 S000294 10-Feb-2000 (last modified) seki Sequence found in the maize (

  17. Detection of outliers in BL(1,1,1,1 Models using Least Squares Method

    Directory of Open Access Journals (Sweden)

    Ibrahim Mohamed

    2006-07-01

    Full Text Available In the literature, various nonlinear time series data was shown to exist. As a result, studies on nonlinear models have been carried out. One of them is bilinear model. Further, there is a possibility that outliers may exist in the data. In this article, the possibility of an outlier appear in a special case of bilinear model, BL(1,1,1,1 is investigated. An outlier detection procedure is proposed.

  18. Materials Science Research Rack-1 (MSRR-1)

    Science.gov (United States)

    2001-01-01

    This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD). This image is from a digital still camera; higher resolution is not available.

  19. Room #1. (Strandgade 10, 1. sal)

    DEFF Research Database (Denmark)

    Møller-Nielsen, Peter; Gejl Kristensen, Jette

    Min indgangsvinkel til arbejdet med Virtual Reality ( VR ) er først og fremmest en simpel nysgerrighed overfor det nye medie. Min billedkunstneriske opdragelse strækker sig fra det klassisk disciplinerede igennem den modernistiske historie til det intervenerende eksperimenterende, som karakterise...... skabt for panoramabiografen i Center for Avanceret Visualisering og Interaktion ( CAVI ) [1] ved Aarhus Universitet. Baggrunden for projektet er beskrevet i [2]. De følgende reflektioner ser projektet alene fra programmørens synspunkt....

  20. Trichlorido(1-ethylpiperazin-1-iumcobalt(II

    Directory of Open Access Journals (Sweden)

    Abdelhamid Chiheb Dhieb

    2014-05-01

    Full Text Available In the title complex, [Co(C6H15N2Cl3], the Co2+ ion is coordinated in a distorted tetrahedral fashion by three chloride ions and one N atom of the piperazine ring; the ring adopts a chair conformation with the N—Co and N—CEt bonds in equatorial orientations. In the crystal, molecules are connected by N—H...Cl hydrogen bonds, generating (10-1 sheets.

  1. The LIFE Model v1.1

    OpenAIRE

    P. Wheatley(University of Warwick, United Kingdom); Ayris, P.; R Davies; McLeod, R; Shenton, H.

    2007-01-01

    Extract: This document draws together feedback, discussion and review of the LIFE Model from a number of sources: 1. The LIFE and LIFE2 Project Teams, and the staff of their institutions 2. Feedback from review by independent economics expert 3. The LIFE Project Conference 4. Early adopters of the Life Model (particularly the Royal Danish Library, State Archives and the State and University Library, Denmark) The result is a revision of the LIFE Model which was first publ...

  2. Preparation of 1-bromoheptacosane

    International Nuclear Information System (INIS)

    Alkybromides are ones of the main organic precursors for fatty acids and alcohols labelling with Carbon 1-14. In this work the preparation of 1-bromoheptacosane by bromodescarboxylation of 1-octacosanoic acid is described. The synthesis yielded 80.5% of final product and more than 97% of chemical purity. Clean-up procedure modifications and spectral data bromoheptacosane are also reported

  3. Main: AMMORESIIUDCRNIA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AMMORESIIUDCRNIA1 S000374 31-Jul-2001 (last modified) uchi Motifs (IIU and IID) fou...nd in the Chlamydomonas (C.R.) Nia1 gene promoter; Involved in ammonium-response; Located between -231 and -...219 and also between -76 and -65; Involved in Nia1 transcription activation; W=T/A; nitrate reductase; ammonium response; Chlamydomonas reinhardtii GGWAGGGT ...

  4. Main: AMMORESVDCRNIA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AMMORESVDCRNIA1 S000376 31-Jul-2001 (last modified) uchi Motif (VD) found in the Ch...lamydomonas (C.R.) Nia1 gene promoter; Located between -33 and -8; Involved in Nia1 transcription activation; nitrate reductase; amm

  5. Main: EECCRCAH1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available EECCRCAH1 S000494 24-April-2006 (last modified) kehi EEC; Consensus motif of the tw...o enhancer elements, EE-1 and EE-2, both found in the promoter region of the Chlamydomonas Cah1 (encoding a periplasmic ca

  6. Main: GAREHVAMY1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available GAREHVAMY1 S000038 17-May-1998 (last modified) kehi GARE (gibberellic acid responsi...ve element) of barley (H.v.) alpha-amylase gene (Amy 1/6-4); GA3; gibberellic acid; GA; GA3; amylase; Amy1/6-4; GARE; barley (Hordeum vulgare) GGCCGATAACAAACTCCGGCC ...

  7. Main: WBOXHVISO1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available WBOXHVISO1 S000442 28-Jan-2004 (last modified) kehi SUSIBA2 bind to W-box element i...n barley iso1 (encoding isoamylase1) promoter; sugar; SURE; patatin; WRKY; isoamylase; SUSIBA2; Hordeum vulgare (barley) TGACT ...

  8. Reference: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available IDRSZMFER1 Petit JM, van Wuytswinkel O, Briat JF, Lobreaux S. Characterization of a...n iron-dependent regulatory sequence involved in the transcriptional control of AtFer1 and ZmFer1 plant ferritin genes by iron. J Biol Chem. 276:5584-5590. (2001) PubMed: 11092880 ...

  9. Main: ABRELATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ABRELATERD1 S000414 01-August-2006 (last modified) kehi ABRE-like sequence (from -1...99 to -195) required for etiolation-induced expression of erd1 (early responsive to dehydration) in Arabidopsis; ABRE; etiolation; erd; Arabidopsis thaliana ACGTG ...

  10. Main: TAAAGSTKST1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available TAAAGSTKST1 S000387 20-Feb-2002 (last modified) uchi TAAAG motif found in promoter ...ecific gene expression; KST1 gene encodes a K+ influx channel of guard cells; See S000265; KST1; Dof; guard cell; Solanum tuberosum (potato) TAAAG ...

  11. Main: RSEPVGRP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available RSEPVGRP1 S000099 13-Feb-2001 (last modified) kehi RSE (root-specific element) of bean (P.v.) GRP1....8 gene; consensus sequence;See also S000288 and S000289; root; GRP1.8; bean (Phaseolus vulgaris) CAACTTTCATAT ...

  12. Porcine SLITRK1

    DEFF Research Database (Denmark)

    Larsen, Knud Erik; Momeni, Jamal; Farajzadeh, Leila;

    2014-01-01

    The membrane protein SLITRK1 functions as a developmentally regulated stimulator of neurite outgrowth and variants in this gene have been implicated in Tourette syndrome. In the current study we have cloned and characterized the porcine SLITRK1 gene. The genomic organization of SLITRK1 lacks intr...

  13. Psychoneuroimmunology and HIV-1.

    Science.gov (United States)

    Antoni, Michael H.; And Others

    1990-01-01

    Presents evidence describing benefits of behavioral interventions such as aerobic exercise training on both psychological and immunological functioning among high risk human immunodeficiency virus-Type 1 (HIV-1) seronegative and very early stage seropositive homosexual men. HIV-1 infection is cast as chronic disease for which early…

  14. 1. Il software

    OpenAIRE

    Musilli, Giorgio

    2014-01-01

    1.1. Il sistema 1.1.1. Un quasi monopolio Windows è una famiglia di ambienti e sistemi operativi (con interfaccia grafica a finestre) prodotti dalla Microsoft Corporation. Il primo sistema Windows risale al novembre 1985, ma già in precedenza (agosto 1981 - giugno 1982) l'azienda di Redmond aveva avuto un grande successo commerciale con il sistema MS-DOS, ottenuto sviluppando il codice del sistema CPM-86 della Seattle Computer Product, soprattutto grazie alla decisione di IBM di inserirlo nei...

  15. Technology in L1

    DEFF Research Database (Denmark)

    Elf, Nikolaj Frydensbjerg; Hanghøj, Thorkild; Skaar, Håvard;

    2015-01-01

    no systematic overview of the documented possibilities and challenges related to the use of technology in L1. At the same time, there is terminological confusion in use of ‘technology’ and related concepts in L1. Finally, there is a general lack of critical reflection on the relation between technological...... developments, political rhetoric, and the development of L1 teaching and learning as a social practice related to specific contexts and actors. Thus, the paper attempts to answer three interrelated research questions: 1) what do we mean when we talk about ‘technology’ in L1?; 2) based on a systematic review...

  16. Melaminium nitrate–melamine–water (1/1/1

    Directory of Open Access Journals (Sweden)

    Farook Adam

    2010-11-01

    Full Text Available In the crystal structure of the title salt, C3H7N6+·NO3−·C3H6N6·H2O, the asymmetric unit consists of two neutral melamine (1,3,5-triazine-2,4,6-triamine molecules, two melaminium cations, two nitrate anions and two solvent water molecules. One of the nitrate anions is disordered over two sets of positions, with a refined occupancy ratio of 0.909 (3:0.091 (3. The cations and neutral molecules are approximately planar, with maximum deviations of 0.018 (2, 0.024 (2, 0.019 (2 and 0.007 (2 Å for each, respectively. In the crystal structure, melaminium cations and netural melamine molecules self-assemble via N—H...N hydrogen bonds to form a supramolecular hexagonal-shaped motif. In addition, the nitrate anions and water molecules are connected by N—H...O hydrogen bonds to form a three-dimensional network.

  17. Prokineticin1 and pregnancy.

    Science.gov (United States)

    Alfaidy, Nadia

    2016-06-01

    Prokineticin 1 (PROK1), also called EG-VEGF, is a peptide of 86 amino acids with multiple biological functions. PROK1 acts via two G-protein coupled receptors: PROKR1 PROKR2. PROK1 is highly expressed in the placenta. This article reports the expression and the role of PROK1 during normal and pathological pregnancies: (i) during early pregnancy, PROK1 exhibits a peak of placental expression shortly before the establishment of the feto-maternal circulation; (ii) its receptors, PROKR1 PROKR2 are highly expressed in human placenta; (iii) its expression is increased by hypoxia; (iv) PROK1 inhibits extravillous trophoblasts migration and invasion and increases their proliferation and survival; (v) PROK1 is also a pro-angiogenic placental factor that increases microvascular placental endothelial cells proliferation, migration, invasion, and permeability. Circulating PROK1 levels are five times higher in pregnant women during the first trimester compared to the second and third trimesters. Also, its serum levels are higher in patients with preeclampsia (PE) and in patients with isolated intra-uterine growth restriction (IUGR). In mice, maintaining high level of PROK1 beyond its normal period of production (>10.5dpc) reproduces symptoms of PE. To date, our results demonstrated that PROK1 is a central factor of human placentation with direct roles both in the control of trophoblast invasion and villous growth. Thus, a failure in the expression of PROK1 and/or its receptor during pregnancy may contribute to the development of PE and/or IUGR. Besides theses original findings, we also report a direct role of this factor in parturition. PMID:27172869

  18. Data of evolutionary structure change: 1D1SB-1QLJA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1D1SB-1QLJA 1D1S 1QLJ B A GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIK...EMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQL...ne>GLY CA 380 VAL CA 377 1QL...J A 1QLJA LKNDLSMPRGT

  19. 1-Methylpiperazine-1,4-diium dipicrate

    Directory of Open Access Journals (Sweden)

    Grzegorz Dutkiewicz

    2011-02-01

    Full Text Available In the crystal structure of the title compound [systematic name: 1-methylpiperazine-1,4-diium bis(2,4,6-trinitrophenolate], C5H14N22+·2C6H2N3O7−, the ionic components are connected by relatively strong N—H...O hydrogen bonds into centrosymmetric six-membered conglomerates, which comprise two dications and four anions. Besides Coulombic interactions, only weak C—H...O interactions and some stacking between picrates (separation between the planes of ca. 3.4 Å but only a small overlapping can be identified between these `building blocks' of the crystal structure. The piperazine ring adopts a chair conformation with the methyl substituent in the equatorial position. In the picrate anions, the twist angles of the nitro groups depend on their positions relative to the phenolate O atom: it is much smaller for the NO2 groups para to the C—O− group [15.23 (9and 3.92 (14°] than for the groups in the ortho positions [28.76 (13–39.84 (11°].

  20. Thermochemistry of 1,1,3,3-tetramethylguanidine and 1,1,3,3-tetramethylguanidinium nitrate

    International Nuclear Information System (INIS)

    Graphical abstract: - Highlights: • The enthalpy of formation of 1,1,3,3-tetramethylguanidinium nitrate was determined by combustion calorimetry. • The cohesive energy of liquid 1,1,3,3-tetramethylguanidinium nitrate was evaluated. • The crystal structure of 1,1,3,3-tetramethylguanidinium nitrate was determined by single crystal X-ray diffraction. • ΔfHmo (l/g) of 1,1,3,3-tetramethylguanidine (tmg) were obtained by solution and Calvet calorimetry. • ΔfHmo (g) calculated by the W1-F12 procedure was in excellent agreement with the corresponding experimental value. - Abstract: Considerable efforts have recently been made to investigate how the structure of protic ionic liquids determines some of their most important properties for technological applications (e.g. low vapour pressure, conductivity). In contrast, the assessment of cohesive energies (which are also linked to those properties) based on thermodynamic results is still practically unexplored. This problem is addressed here for 1,1,3,3-tetramethylguanidinium nitrate, [Htmg][NO3], through a combination of experimental and computational chemistry results at the reference temperature of 298.15 K. The standard molar enthalpies of formation, ΔfHmo([Htmg][NO3],cr)=-(311.8±2.3)kJ·mol-1, and fusion, ΔfusHmo([Htmg][NO3])=16.2±3.8kJ·mol-1, of solid 1,1,3,3-tetramethylguanidinium nitrate (form I polymorph) were obtained by combustion and differential scanning calorimetry, respectively. From these results ΔfHmo([Htmg][NO3],l)=-(295.6±4.4)kJ·mol-1 could be derived. Also determined were the standard molar enthalpies of formation, ΔfHmo(tmg, l)=7.7±2.8kJ·mol-1, and vaporisation, ΔvapHmo(tmg,l)=50.0±1.2kJ·mol-1, of 1,1,3,3-tetramethylguanidine, by reaction solution and Calvet-drop microcalorimetry, respectively, leading to ΔfHmo(tmg,g)=57.7±3.0kJ·mol-1. This result is in excellent agreement with ΔfHmo(tmg,g)=58.4±4.0kJ·mol-1, obtained from the ab initio calculation of the standard molar

  1. [NDM-1: the superbug?].

    Science.gov (United States)

    Pittalis, S; Ferarro, F; Puro, V

    2011-12-01

    A novel type of carbapenemase, New Delhi metallo beta-lactamase 1 (NDM 1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM 1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The NDM 1 producing Gram-negative bacteria are mainly Enterobacteriaceae, which can cause colonization or fatal infections, with worrying antimicrobial susceptibility profiles: some isolates have developed resistance to practically all available antibiotics. Is the NDM-1 the super-bug? Are we in the post-antibiotic era? This review is a summary of currently available knowledge of NDM-1 that draws attention to future antimicrobial resistance scenarios. PMID:22212161

  2. AC1 Wing

    Directory of Open Access Journals (Sweden)

    Adrian DOBRE

    2010-03-01

    Full Text Available The AC1 wing replaces the old wing of the wind tunnel model AEROTAXI, which has been made at scale 1:9. The new wing is part of CESAR program and improves the aerodynamic characteristics of the old one. The geometry of the whole wing was given by FOI Sweden and position of AC1 wing must coincide with the structure of the AEROTAXI model.

  3. AC1 Wing

    OpenAIRE

    Adrian DOBRE

    2010-01-01

    The AC1 wing replaces the old wing of the wind tunnel model AEROTAXI, which has been made at scale 1:9. The new wing is part of CESAR program and improves the aerodynamic characteristics of the old one. The geometry of the whole wing was given by FOI Sweden and position of AC1 wing must coincide with the structure of the AEROTAXI model.

  4. SINTEZA ( R )-1-AMINOINDANA

    OpenAIRE

    Prudič, Darja

    2014-01-01

    (R)-1-aminoindan je pomemben intermediat za sintezo zdravilne farmacevtske učinkovine rasagilina, (R)(+)-N-propargil-1-aminoindana, oz. njegove soli. Zdravila osnovana na navedeni učinkovini se uporabljajo za zdravljenje indikacij Parkinsonove bolezni, motenj spomina, demence tipa Alzheimerjeve bolezni, depresije in hiperaktivnega sindroma pri otrocih. Magistrska naloga temelji na razvoju učinkovite sinteze (R)-1-aminoindana in preveritvi ter potrditvi ustreznosti tega ključnega intermediata ...

  5. BAP1 and Cancer

    OpenAIRE

    Carbone, Michele; Yang, Haining; Pass, Harvey I.; Krausz, Thomas; Joseph R. Testa; Gaudino, Giovanni

    2013-01-01

    BAP1 is a deubiquitylase that is found associated with multi-protein complexes that regulate key cellular pathways, including the cell cycle, cellular differentiation, cell death, gluconeogenesis and the DNA damage response (DDR). Recent findings indicate that germline BAP1 mutations cause a novel cancer syndrome, characterized, at least in the affected families studied so far, by the onset at an early age of benign melanocytic skin tumours with mutated BAP1, and later in life by a high incid...

  6. On 1/f Noise

    OpenAIRE

    Li, Ming; Zhao, Wei

    2012-01-01

    Due to the fact that 1/f noise gains the increasing interests in the field of biomedical signal processing and living systems, we present this introductive survey that may suffice to exhibit the elementary and the particularities of 1/f noise in comparison with conventional random functions. Three theorems are given for highlighting the particularities of 1/f noise. The first says that a random function with long-range dependence (LRD) is a 1/f noise. The secondindicates that a heavy-tailed r...

  7. What If w < -1 ?

    CERN Document Server

    McInnes, B

    2002-01-01

    The cosmological "equation of state parameter", w, is equal to -1 for a true cosmological constant, and is greater than -1 for quintessence. There is a widespread reluctance to consider the remaining possibility, w < -1, though in fact there is a variety of theoretical and observational evidence in favour of this range. We briefly discuss some of the objections to w < -1 and show that each of them can readily be circumvented. We also briefly consider what string theory has to say about this.

  8. 2009 H1N1 Influenza 2009 H1N1 Influenza

    Directory of Open Access Journals (Sweden)

    Seth J. Sullivan, MD; Robert M. Jacobson, MD; Walter R. Dowdle, PhD; and Gregory A. Poland

    2011-04-01

    Full Text Available Within 2 months of its discovery last spring, a novel influenza A (H1N1 virus, currently referred to as 2009 H1N1, caused the first influenza pandemic in decades. The virus has caused disproportionate disease among young people with early reports of virulence similar to that of seasonal influenza. This clinical review provides an update encompassing the virology, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of the 2009 H1N1 virus. Because information about this virus, its prevention,and treatment are rapidly evolving, readers are advised to seek additional information. We performed a literature search of PubMed using the following keywords: H1N1, influenza, vaccine, pregnancy, children, treatment, epidemiology, and review. Studies were selected for inclusion in this review on the basis of their relevance. Recent studies and articles were preferred.

    El Editor de este número especial agradece la autorización expresa, mediante comunicación escrita en nuestro poder, de los autores del trabajo “2009 H1N1 Influenza”, así como de los editores de la revista Mayo Clinic Proceedings, para su reproducción, como publicación secundaria en Medisur, artículo de revisión seleccionado por nosotros, que resume buena parte de los nuevos conocimientos adquiridos a partir de la literatura médica reciente relacionada con esta pandemia, durante el año 2009.

    De este modo, el artículo que a continuación de reproduce para los lectores de Medisur, está basado íntegramente en el estudio previamente publicado como: Sullivan SJ, Jacobson RM, Dowdle WR, Poland GA. 2009 H1N1 Influenza. Mayo Clin Proc. 2010;85(1:64-76.

    A continuación el resumen:

    Within 2 months of its discovery last spring, a novel influenza A (H1N1 virus, currently referred to as 2009 H1N1, caused the first influenza pandemic in decades. The virus has caused disproportionate disease among young people with early reports of virulence similar

  9. Reference: BOXCPSAS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available BOXCPSAS1 Ngai N, Tsai FY, Coruzzi G Light-induced transcriptional repression of the pea AS1 gene: identific...ation of cis-elements and transfactors Plant J 12:1021-1234 (1997) PubMed: 9418044; ...

  10. Reference: MYBCOREATCYCB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available haracterization of cis-acting element involved in cell cycle phase-independent activation of Arath;CycB1;1 transcription and identifi...cation of putative regulatory proteins. Plant Mol Biol. 50:111-127 (2002). PubMed: 12139003 ...

  11. Reference: BOXBPSAS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available BOXBPSAS1 Ngai N, Tsai FY, Coruzzi G Light-induced transcriptional repression of the pea AS1 gene: identific...ation of cis-elements and transfactors Plant J 12:1021-1234 (1997) PubMed: 9418044; ...

  12. A Distributed Tier-1

    DEFF Research Database (Denmark)

    Fischer, Lars; Grønager, Michael; Kleist, Josva;

    2008-01-01

    The Tier-1 facility operated by the Nordic DataGrid Facility (NDGF) differs significantly from other Tier-1s in several aspects: firstly, it is not located at one or a few premises, but instead is distributed throughout the Nordic countries; secondly, it is not under the governance of a single or...

  13. AAU-BOT1

    DEFF Research Database (Denmark)

    Svendsen, Mads Sølver; Helbo, Jan; Hansen, Michael Rygaard;

    2009-01-01

    This paper describes the development of the humanoid robot AAU-BOT1. The purpose of the robot is to investigate human-like walking and in this connection, test prosthetic limbs. AAU-BOT1 has been designed with modularity in mind making it possible to replace, e.g. the lower leg to test transfemoral...

  14. Main: CACTFTPPCA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ion of the phosphoenolpyruvate carboxylase (ppcA1) of the C4 dicot F. trinervia; Y=T/C; mesohpyll; CACT; Flaveria trinervia YACT ... ...CACTFTPPCA1 S000449 19-August-2004 (last modified) kehi Tetranucleotide (CACT) is a

  15. Main: CAREOSREP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available CAREOSREP1 S000421 28-November-2004 (last modified) kehi CAREs (CAACTC regulatory e...lements) found in the promoter region of a cystein proteinase (REP-1) gene in rice; aleurone; GARE; gibberellin; seed; Oryza sativa (rice) CAACTC ...

  16. Main: ACGTATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ACGTATERD1 S000415 03-Jun-2003 (last modified) kehi ACGT sequence (from -155 to -15...2) required for etiolation-induced expression of erd1 (early responsive to dehydration) in Arabidopsis; ACGT; etiolation; erd; Arabidopsis thaliana ACGT ...

  17. Reference: MYCATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available MYCATERD1 Simpson SD, Nakashima K, Narusaka Y, Seki M, Shinozaki K, Yamaguchi-Shinozaki K. Two differ...ent novel cis-acting elements of erd1, a clpA homologous Arabidopsis gene function in indu

  18. Reference: ACGTATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ACGTATERD1 Simpson SD, Nakashima K, Narusaka Y, Seki M, Shinozaki K, Yamaguchi-Shinozaki K. Two differ...ent novel cis-acting elements of erd1, a clpA homologous Arabidopsis gene function in ind

  19. Reference: SPHCOREZMC1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SPHCOREZMC1 McCarty DR, Hattori T, Carson CB, Vasil V, Lazar M, Vasil IK The Vivipa...rous-1 developmental gene of maize encodes a novel transcriptional activator Cell 66: 895-905 (1991) PubMed: 1889090; ...

  20. Diabetes Type 1

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. With type 1 diabetes, your pancreas does not make insulin. Insulin is ... kidneys, nerves, and gums and teeth. Type 1 diabetes happens most often in children and young adults ...

  1. Moschos' 1. Idyl

    DEFF Research Database (Denmark)

    Nielsen, Thomas Heine

    2009-01-01

    genudgivelse med indledning af Simon meislings oversættelse fra 1824 af Moschos' 1. idyl, Den bortløbne eros. Udgivelsesdato: 2009......genudgivelse med indledning af Simon meislings oversættelse fra 1824 af Moschos' 1. idyl, Den bortløbne eros. Udgivelsesdato: 2009...

  2. Main: ELRECOREPCRP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ELRECOREPCRP1 S000142 22-June-2006 (last modified) kehi ElRE (Elicitor Responsive E...ite; W-box found in thioredoxin h5 gene in Arabidopsis (Laloi et al.); Elicitor; PR1; ElRE; ELRE; ERE; W box

  3. Main: LREBOXIPCCHS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available LREBOXIPCCHS1 S000302 16-Feb-2001 (last modified) seki BoxI; Light responsive element (LR...YB repeat; chalcone synthase; CHS; light; Box I; LRE; PcMYB1; MRECHS; MYB; leaf; shoot; parsley (Petroselinum crispum) AACCTAACCT ...

  4. Reference: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available IDRSZMFER1 Fourcroy P, Vansuyt G, Kushnir S, Inze D, Briat JF. Iron-regulated expre...ssion of a cytosolic ascorbate peroxidase encoded by the APX1 gene in Arabidopsis seedlings. Plant Physiol. 134: 605-613 (2004). . PubMed: 14739345 ...

  5. The No.1 Priority

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    At the beginning of each year, the Central Committee of theCommunist Party of China and the State Council jointly release thefirst document of the year, dubbed the No. 1 Document. The issuediscussed in the No. 1 Document is, of course, the most important to

  6. The No.1 Priority

    Institute of Scientific and Technical Information of China (English)

    YU SHUJUN

    2010-01-01

    @@ At the beginning of each year, the Central Committee of the Communist Party of China and the State Council jointly release the first document of the year, dubbed the No.1 Document. The issue discussed in the No.1 Document is, of course, the most important to the current economic and social development of the country.

  7. Farmers’ No.1 Concern

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Rural residents anticipate the impact of the No.1Document on China’s countryside in 2010 Liu Limin, a farmer living in Lanxian County, Shanxi Province, knows theins and outs of the No. 1 Document.From memory, Liu can recite major

  8. Final report Isafruit wp 1.1 Isafruit deliverable 1.1.7

    NARCIS (Netherlands)

    Groot, M.J.; Benninga, J.; Hennen, W.H.G.J.

    2007-01-01

    The aim of Work Package 1.1 EUFCON of Isafruit is to conduct a thorough analysis of European Fruit Consumption in order to identify and understand major consumption trends and consumption patterns of European Fruit Consumption. Additionally, the information obtained in this work package (WP) will pr

  9. A Note on Indefinite Equation1/x+1/y+1/z +1/w+1/xyzw=0%关于不定方程1/x+1/y+1/z +1/w+1/xyzw=0的一点注记

    Institute of Scientific and Technical Information of China (English)

    管训贵

    2010-01-01

    利用初等方法研究了不定方程1/x+1/y+1/xyzw=1/z+1/w以及1/x+1/y+1/z=1/w+1/xyzw的正整数解问题,分别给出了它们的全部正整数解的公式:(x,y,z,w)=(n+k,n(n+k)-d/k,n2(n+k)2-n(n+k)d-k/kd,n)其中n,k,d为正整数,满足d|n2(n+k)2-k),d<n(n+k)-k,k|(n2-d) ;以及 (x,y,z,w)=(n+k,n(n+k)+d/k,n2(n+k)2+n(n+k)d-k/kd,n),其中n,k,d为正整数,满足 d|(n2(n+k)2-k) ,d<n2(n+k)2-k,k|(n2+d).

  10. IUPHAR Review 1

    DEFF Research Database (Denmark)

    Harmar, Anthony J; Fahrenkrug, Jan; Gozes, Illana;

    2012-01-01

    (GHRH). VIP and PACAP exert their actions through three G protein-coupled receptors (GPCRs) - PAC(1) , VPAC(1) and VPAC(2) - belonging to class B (also referred to as class II, or secretin receptor-like GPCRs). This family comprises receptors for all peptides structurally related to VIP and PACAP......, and also receptors for parathyroid hormone, corticotropin-releasing factor, calcitonin and related peptides. PAC(1) receptors are selective for PACAP, whereas VPAC(1) and VPAC(2 ) respond to both VIP and PACAP with high affinity. VIP and PACAP play diverse and important roles in the CNS, with functions...... in the control of circadian rhythms, learning and memory, anxiety and responses to stress and brain injury. Recent genetic studies also implicate the VPAC(2) receptor in susceptibility to schizophrenia and the PAC(1) receptor in post-traumatic stress disorder. In the periphery, VIP and PACAP play important roles...

  11. Influenza Stigma during the 2009 H1N1 Pandemic

    OpenAIRE

    Earnshaw, Valerie A.; Quinn, Diane M.

    2013-01-01

    The current study examines the extent to which H1N1 was stigmatized at the height of the 2009 H1N1 pandemic in the U.S. and explores the role that H1N1 stigma played in people’s desire for physical distance from others with H1N1. H1N1 was the most stigmatized disease, with participants endorsing greater prejudice towards people with H1N1 than people with cancer or HIV/AIDS. Further, H1N1 stigma partially mediated the relationship between participants’ perceptions that H1N1 was threatening and...

  12. 1,3-Diphenylisobenzofuran

    Directory of Open Access Journals (Sweden)

    Kristapher E. Fischer

    2008-04-01

    Full Text Available The structure of the title compound, 1,3-diphenyl-2-benzofuran, C20H14O, exhibits a distinct alternation of short [mean 1.361 (3 Å] and long [mean 1.431 (3 Å] C—C bonds around the benzofuran ring system, indicating a predominantly polyene character. Over 60 Diels–Alder adducts of this commercially available furan have been structurally characterized, but this is the first report of the structure of the parent compound.

  13. Linac 1, inner structure

    CERN Multimedia

    1968-01-01

    This photo shows the inner structure of Linac 1. As injector to the PS, and later to the Booster, Linac 1 accelerated protons to 50 MeV, but it has also accelerated heavier ions. Fitted with a 520 keV RFQ pre-injector (instead of the original Cockcroft-Walton generator), it delivered protons and heavy ions to LEAR, from 1982 to 1992. After 33 years of faithful service, Linac 1 was dismantled in 1992 to make room for Linac 3 (Pb ions).

  14. Spacelab Life Sciences-1

    Science.gov (United States)

    Dalton, Bonnie P.; Jahns, Gary; Meylor, John; Hawes, Nikki; Fast, Tom N.; Zarow, Greg

    1995-01-01

    This report provides an historical overview of the Spacelab Life Sciences-1 (SLS-1) mission along with the resultant biomaintenance data and investigators' findings. Only the nonhuman elements, developed by Ames Research Center (ARC) researchers, are addressed herein. The STS-40 flight of SLS-1, in June 1991, was the first spacelab flown after 'return to orbit', it was also the first spacelab mission specifically designated as a Life Sciences Spacelab. The experiments performed provided baseline data for both hardware and rodents used in succeeding missions.

  15. ATG16L1

    DEFF Research Database (Denmark)

    Salem, Mohammad; Ammitzboell, Mette; Nys, Kris;

    2015-01-01

    Genetic variations in the autophagic pathway influence genetic predispositions to Crohn disease. Autophagy, the major lysosomal pathway for degrading and recycling cytoplasmic material, constitutes an important homeostatic cellular process. Of interest, single-nucleotide polymorphisms in ATG16L1...... (autophagy-related 16-like 1 [S. cerevisiae]), a key component in the autophagic response to invading pathogens, have been associated with an increased risk of developing Crohn disease. The most common and well-studied genetic variant of ATG16L1 (rs2241880; leading to a T300A conversion) exhibits a strong...

  16. Open Praxis, volumen 1 issue 1

    Directory of Open Access Journals (Sweden)

    Editor Open Praxis

    2007-01-01

    Full Text Available Table of Contents - A Study on the Importance of Fostering Trust in a Distance Learning Community Sónia Sousa, David Lamas & Brian Hudson (1-10 - Teacher Upgrading through Distance Education in a South African Context C. G. Kruger & Prof. E. J. Spamer (11-19 - An Investigation into Delivery of On-Line Courses within an Early Childhood Teacher Education Distance Programme in New Zealand Susan E. Smart (20-29 - Transnational Online Project Management Curriculum Model for Engineering Students Enrique Benimeli Bofarull, Anke Muendler, Peter Haber (30-39 - China Rural Distance Education and Construction of the New Countryside Li Fanghong & Zeng Yichun (40-46 - E-Learning in Japan: Steam Locomotive on Shinkansen Ali E. Ozkul, Ph.D. & Kumiko Aoki, Ph.D.  (47-55 - Widening Access to Higher Education: Open and Distance Learning in Higher Education Setting in Indonesia Paulina Pannen (56-65 - Research and Development of a Costing Toolkit for Distance, Flexible and ICT-Based Education for Teacher Development in Africa Frank R J Banks (66-75 - Fostering E-Learning in Medical Education: The Eurovacc Team Experience Guilherme Andrade Marson, Nathalie Debard, Jean-Pierre Kraehenbuhl, Pascal Py, Yan Cornneille, Laurent Richard, Alain Meystre (76-86 - Program Upgrading Teachers in Education Irene Hardy de Gómez (87-95 - ICT based learning strategies for Educating nomads Yogesh Kulkarni & Dr. Madhav Gaikwad (96-102 - Information and Communication Technology and Distance Education in Brazil Marta de Campos Maia & Fernando de Souza Meirelles (103-112 - ICDE’s interview with Susan D’Antoni, UNESCO International Institute for Educational Planning (IIEP (113-117 - ICDE Task Force Open Educational Resources – Inquiry Results (118-125 - 22nd ICDE – World Conference on Distance Education: Facts and figures (126-131

  17. Data of evolutionary structure change: 1COBB-1F1GD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1COBB-1F1GD 1COB 1F1G B D ATKAVCVLKGDGPVQGTIHFEAKG--DTVVVTGSITGLTE-GDHGFHVHQFGD...NTQGCTSAGPHFNPLSKKHGGPKDEERHVGDLGNVTADKNGVAIVDIVDPLISLSGEYSIIGRTMVVHEKPDDLGRGGNEESTKTGNAGSRLAC...GVIGIAK -VQAVAVLKGDAGVSGVVKFEQASESEPTTVSYEIAGNSPNAERGFHIHEFGDATNGCVSAGPHFNPFKKTHGAPTDEVRHVGDMGN...VKTDENGVAKGSFKDSLIKLIGPTSVVGRSVVIHAGQDDLGKGDTEESLKTGNAGPRPACGVIGLTN ...pdbID>1F1G D 1F1GD FEQASESEPTTV

  18. Data of evolutionary structure change: 1BU1D-1QLYA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1BU1D-1QLYA 1BU1 1QLY D A -IIVVALYDYEAIHHEDLSFQKGDQMVVLEESG-EWWKA...RSLATRKEGYIPSNYVARV- LKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDK-NGQEGYIPSNYVTEAE -...A 277 TRP CA 316 LYS CA 330 ALA CA 359 1QL...Y A 1QLYA LEESNLPWW...21347046 2.311821937561035 1 1QL

  19. Type 1 diabetes

    Science.gov (United States)

    ... your diabetes. But, you are the most important person in managing your diabetes. You should know the basic steps ... to your doctor before starting any exercise program. People with type 1 ... MANAGING YOUR BLOOD SUGAR Checking your blood sugar level ...

  20. Main: MARABOX1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available MARABOX1 S000063 13-Feb-2001 (last modified) kehi A-box found in SAR(scaffold attac...hment region; or matrix attachment region, MAR); MAR; SAR; matrix; A-box; scaffold; Drosophila; fly; AATAAAYAAA ...

  1. Mark 1 Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

  2. Reference: CACTFTPPCA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available CACTFTPPCA1 Gowik U, Burscheidt J, Akyildiz M, Schlue U, Koczor M, Streubel M, West...he promoter of the C4 phosphoenolpyruvate carboxylase gene. Plant Cell. 16:1077-1090(2004) PubMed: 15100398 ...

  3. A1C Test

    Science.gov (United States)

    ... to minimize the complications caused by chronically elevated glucose levels, such as progressive damage to body organs like the kidneys, eyes, cardiovascular system, and nerves. The A1c test result ...

  4. Reference: MYCATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available MYCATERD1 Tran LS, Nakashima K, Sakuma Y, Simpson SD, Fujita Y, Maruyama K, Fujita ...ible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehy

  5. Main: ARE1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ARE1 S000022 16-Jan-1998 (last modified) kehi ARE (antioxidant response element); antioxidant... response element of rat glutathione S-transferase Ya subunit, and rat NAD(P)H:quinone reductase genes; antioxidant

  6. Type 1 diabetes

    DEFF Research Database (Denmark)

    Green, Anders; Kyvik, Kirsten Ohm

    2001-01-01

    Prediction of Type 1 diabetes at individual level is relevant for any possible intervention before clinical disease develops. Currently available markers of Type 1 diabetes include genetic specificities and immune markers, in addition to a positive family history. This chapter reviews the measures...... and methods of importance in predicting Type 1 diabetes. Based on numerical examples it is demonstrated that available markers have a low level of performance, even when combined. Even so, combined marker information may allow for the identification of the large majority of the general population who...... is at very low disease risk. The impact at population level of predicting Type 1 diabetes varies between societies because the performance of markers depends on levels of disease risk and distribution of markers within a population. The incorporation of the influence of non-genetic etiological factors may...

  7. Chapter 1: Introduction

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-01-18

    This report describes analysis undertaken by EERE to better understand the extent to which the technologies and market improvements funded by its fiscal year (FY) 2006 Budget Request1 will make energy more affordable, cleaner, and more reliable.

  8. Probability 1/e

    Science.gov (United States)

    Koo, Reginald; Jones, Martin L.

    2011-01-01

    Quite a number of interesting problems in probability feature an event with probability equal to 1/e. This article discusses three such problems and attempts to explain why this probability occurs with such frequency.

  9. Main: LREBOXIIPCCHS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available LREBOXIIPCCHS1 S000303 10-Feb-2000 (last modified) seki BoxII; Light responsive element (LR...02; chalcone synthase; CHS; light; Box II; LRE; leaf; shoot; parsley (Petroselinum crispum) TCCACGTGGC ...

  10. Main: PYRIMIDINEBOXHVEPB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available PYRIMIDINEBOXHVEPB1 S000298 10-Feb-2000 (last modified) seki Pyrimidine box found i... induction; See S000297, S000259; EPB; cysteine proteinase; GA; ABA; GARE; pyrimidine box; seed; aleurone; barley (Hordeum vulgare) TTTTTTCC ...

  11. Reference: PYRIMIDINEBOXHVEPB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available PYRIMIDINEBOXHVEPB1 Cercos M, Gomez-Cadenas A, Ho THD Hormonal regulation of a cyst...dinated gene expression regulated by gibberellins and abscisic acid Plant J 19: 107-118 (1999) PubMed: 10476058 ...

  12. Reference: CAREOSREP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available CAREOSREP1 Sutoh K, Yamauchi D. Two cis-acting elements necessary and sufficient for gibberellin-upre...gulated proteinase expression in rice seeds Plant J. 34:635-645 (2003) PubMed: 12787245; ...

  13. Reference: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available tial involvement of the IDRS cis-element in the developmental and environmental regulation of the AtFer1 ferritin gene from Arabidopsis. Planta. 217: 709-716 (2003) PubMed: 12728319 ...

  14. Main: ABADESI1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ABADESI1 S000007 10-Feb-2000 (last modified) seki Responsive to ABA and desiccation...; Motif I of rice rab16A-D (initially called rab-21); Expressed in seeds late during embryogenesis; Induced

  15. Contaminant Candidate List 1

    Data.gov (United States)

    U.S. Environmental Protection Agency — CCL 1 is a list of contaminants that are currently not subject to any proposed or promulgated national primary drinking water regulations, that are known or...

  16. COMPASS RICH-1

    International Nuclear Information System (INIS)

    RICH-1 is one of the key detectors of the COMPASS experiment at CERN. It is a large acceptance gaseous RICH, designed to perform π/κ separation up to 60 GeV/c. All RICH-1 components are built, most of them have been commissioned during year 2000 COMPASS technical run and the detector will be completed during Spring 2001. We give a description of the detector and report about various technological achievements required by this challenging project

  17. Pesticidrester 1. kvartal 2015

    DEFF Research Database (Denmark)

    Andersen, Jens Hinge; Jensen, Bodil Hamborg

    Resultaterne af den danske pesticidkontrol fra Fødevarestyrelsen og DTU Fødevareinstituttet fra 1. kvartal 2015 viser, at ingen af de påviste sprøjterester udgør en sundhedsmæssig risiko.......Resultaterne af den danske pesticidkontrol fra Fødevarestyrelsen og DTU Fødevareinstituttet fra 1. kvartal 2015 viser, at ingen af de påviste sprøjterester udgør en sundhedsmæssig risiko....

  18. Wozu AT1-Rezeptorantagonisten?

    Directory of Open Access Journals (Sweden)

    Berent R

    2000-01-01

    Full Text Available ACE-Hemmer sind nun seit fast 20 Jahren im klinischen Einsatz. Ihre Effektivität in der Behandlung der arteriellen Hypertonie, der Herzinsuffizienz und bei nephrologischen Erkrankungen wurde durch eine große Zahl an randomisierten, prospektiven Studien belegt. Zusätzlich ist das Nebenwirkungsprofil (inklusive seltener Nebenwirkungen dieser Substanzklasse durch die langjährige Anwendung gut dokumentiert. Unter einer AT1-Rezeptorantagonistentherapie konnte bislang eindeutig gezeigt werden, daß das Auftreten von Nebenwirkungen, im speziellen des Reizhustens, deutlich seltener ist und im Placebobereich liegt, was die Compliance der Patienten sicherlich erhöht. Klinisch finden sich allerdings kaum Unterschiede in der Hämodynamik bei der Einnahme von ACE-Hemmern oder AT1-Rezeptorantagonisten. AT1-Rezeptorantagonisten blockieren sicherlich effektiver die AT1-rezeptorvermittelte Vasokonstriktion, währenddessen sich die ACE-Hemmerwirkung aus einer partiellen Abnahme der Angiotensin-II-Bildung und der Akkumulation von Bradykinin zusammensetzt. Aufgrund der derzeitigen Datenlage kann der AT1-Rezeptorantagonist nicht als Alternative zum ACE-Hemmer empfohlen werden, außer ein Absetzen des ACE-Hemmers ist wegen Nebenwirkungen notwendig. Auch die Kombinationstherapie, AT1-Rezeptorantagonist plus ACE-Hemmer, stellt zum jetzigen Zeitpunkt noch keine etablierte Therapie dar.

  19. aflatoxina b1

    Directory of Open Access Journals (Sweden)

    A. Valdivia

    2004-01-01

    Full Text Available Con el objetivo de probar que la suplementación dietética de ácido elágico (AE o N-Acetilcisteína (NAC en pollos de engorda, atenúa los efectos de una intoxicación aguda por la aflatoxina B1 (AFB1, se intoxicaron con AFB1 pura, tres grupos de diez pollos cada uno (3.0 mb/kg pc, IP. Otros tres grupos recibieron solamente el vehículo (aceite de maíz 2.0 ml/kg pc, IP. Cuatro días antes se administró un alimento testigo, o bien, la misma dieta adicionada con AE (2.5 g/kg o NAC (200 mg/kg pc/6 h. A las 24 horas de la administración de AFB1, se cuantificaron las concentraciones hepáticas de glutatión (GSH, de actividad enzimática específica de la transferasa de glutatión (GST, alanina aminotransferasa, aspartato aminotransferasa y de proteínas hepáticas totales. Los resultados mostraron que NAC atenúa el impacto negativo de la AFB1 sobre el crecimiento corporal y al igual que AE, incrementa la GST y revierte parcialmente los efectos de AFB1 sobre GSH, lo cual sugiere que ambas sustancias pudieran conferir un efecto protector de las aves

  20. 26 CFR 1.23-1 - Residential energy credit.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  1. 26 CFR 1.1377-1 - Pro rata share.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Pro rata share. 1.1377-1 Section 1.1377-1...) INCOME TAXES Small Business Corporations and Their Shareholders § 1.1377-1 Pro rata share. (a) Computation of pro rata shares—(1) In general. For purposes of subchapter S of chapter 1 of the...

  2. 26 CFR 1.50-1 - Restoration of credit.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Restoration of credit. 1.50-1 Section 1.50-1... Computing Credit for Investment in Certain Depreciable Property § 1.50-1 Restoration of credit. (a) In general. Section 49(a) (relating to termination of credit) does not apply to property— (1)...

  3. Main: S1FBOXSORPS1L21 [PLACE

    Lifescience Database Archive (English)

    Full Text Available S1FBOXSORPS1L21 S000223 10-May-1998 (last modified) kehi S1F box conserved both in spinach (S.o.) RPS1... and RPL21 genes encoding the plastid ribosomal protein S1 and L21, respectively; Negativ...e element; Might play a role in downregulating RPS1 and RPL21 promoter activity (Lagrange et al., 1993); See S000211 (SITE1SORPS1...), S000215 (S1FSORPL21); S1F; S1F box; S1F-box; S1; plastid protein; RPS1; RPL21; leaf; negative; spinach (Spinacia oleracea) ATGGTA ...

  4. 26 CFR 1.952-1 - Subpart F income defined.

    Science.gov (United States)

    2010-04-01

    ... applicable to taxable years beginning before January 1, 1967, see 26 CFR 1.952-1(b)(1) (Revisedof April 1..., and (4) The sum of the amount of any illegal bribes, kickbacks, or other payments paid after...

  5. Main: 1E1E [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1E1E トウモロコシ Corn Zea mays L. Beta-Glucosidase, Chloroplast Precursor Name=Glu1; Zea...TDDAYASQEVNGPDGKPIGPPMGNPWIYMYPEGLKDLLMIMKNKYGNPPIYITENGIGDVDTKETPLPMEAALNDYKRLDYIQRHIATLKESIDLGSNVQGYFAWSLLDNFEWFAGFTERYGIVYVDRNNNCTRYMKESAKWLKEFNTAKKPSKKILTPA corn_1E1E.jpg ...

  6. Main: 1E1F [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1E1F トウモロコシ Corn Zea mays L. Beta-Glucosidase, Chloroplast Precursor Name=Glu1; Zea...QRHIATLKESIDLGSNVQGYFAWSLLDNFEWFAGFTERYGIVYVDRNNNCTRYMKESAKWLKEFNTAKKPSKKILTPA corn_1E1F.jpg ...

  7. Sunflower trypsin inhibitor-1.

    Science.gov (United States)

    Korsinczky, Michael L J; Schirra, Horst Joachim; Craik, David J

    2004-10-01

    SFTI-1 is a bicyclic 14 amino acid peptide that was originally isolated from the seeds of the sunflower Helianthus annuus. It is a potent inhibitor of trypsin, with a sub-nanomolar K(i) value and is homologous to the active site region of the well-known family of serine protease inhibitors known as the Bowman-Birk trypsin inhibitors. It has a cyclic backbone that is cross-braced by a single disulfide bridge and a network of hydrogen bonds that result in a well-defined structure. SFTI-1 is amenable to chemical synthesis, allowing for the creation of synthetic variants. Alterations to the structure such as linearising the backbone or removing the disulfide bridge do not reduce the potency of SFTI-1 significantly, and minimising the peptide to as few as nine residues results in only a small decrease in reactivity. The creation of linear variants of SFTI-1 also provides a tool for investigating putative linear precursor peptides. The mechanism of biosynthesis of SFTI-1 is not yet known but it seems likely that it is a gene-coded product that has arisen from a precursor protein that may be evolutionarily related to classic Bowman-Birk inhibitors. PMID:15544530

  8. TRUPACT-1 implementation plan

    Energy Technology Data Exchange (ETDEWEB)

    Hurley, J.D.; Tappen, J.J. (Westinghouse Electric Corp., Albuquerque, NM (United States). Joint Integration Office); Christensen, D.S. (USDOE Joint Integration Office, Albuquerque, NM (United States)) (eds.)

    1985-09-01

    TRUPACT-1, the TRansUranic PACkage Transporter is a packaging designed to transport defense contact handled transuranic (CH-TRU) waste from generating and interim TRU waste storage facilities to the Waste Isolation Pilot Plant (WIPP). Prior to fabrication and procurement of a full fleet, an initial design (TRUPACT-1) will be introduced to the defense TRU waste complex through use in an operational prototype fleet which will consist of Units 1, 2, and 3. In an effort to provide a relatively smooth introduction of the TRUPACT-1, the TRUPACT Technical Team (TTT) has developed the following implementation plan. The plan provides detailed information on user handling opportunities, schedules, equipment, responsibilities, reporting and data collection activities to be performed. The intent of this document is to provide users of the TRUPACT-1 with a guidance document, complete with references, that will allow the smooth introduction of this new transportation system by providing the information necessary for collecting operational, performance and cost data. These data will be used in modeling and full fleet design and procurement activities. In addition, these data will help fine tune procedures in the inspection and maintenance document and the operational document. Additional objectives of this plan are to aid in the establishment of site operational, inspection and maintenance procedures as well as training of site operators and briefing state and local officials.

  9. FABP1 in wonderland.

    Science.gov (United States)

    Prinetti, Alessandro; Mitro, Nico

    2016-08-01

    Cannabinoid receptors hold a core position in the brain and control memory, cognition, movement, and pain sensitivity. sn-2 arachidonoylglycerol (2-AG) activates neuronal cannabinoid receptors as a full agonist. The brain may rely on circulating arachidonic acid to synthesize endogenous cannabinoids. This Editorial highlights a study by Martin and coworkers in the current issue of the Journal of Neurochemistry in which the authors describe, for the first time, that liver acts as a pool of arachidonic acid that under certain conditions feeds the brain to produce endocannabinoids. Therapeutics affecting liver FABP1 levels should take into account that FABP1 represents a fatty acid reservoirs for the brain. Read the highlighted article "FABP-1 gene ablation impacts brain endocannabinoid system in male mice" on page 407. PMID:27329821

  10. Transformation of 1,1,1-trichloroethane in an anaerobic packed-bed reactor at various concentrations of 1,1,1-trichloroethane, acetate and sulfate

    NARCIS (Netherlands)

    deBest, JH; Jongema, H; Weijling, A; Doddema, HJ; Janssen, DB; Harder, W

    1997-01-01

    Biotransformation of 1,1,1-trichloroethane (CH3CCl3) was observed in an anaerobic packed-bed reactor under conditions of both sulfate reduction and methanogenesis. Acetate (1 mM) served as an electron donor. CH3CCl3 was completely converted up to the highest investigated concentration of 10 mu M. 1,

  11. Green syntheses, v.1

    CERN Document Server

    Tundo, Pietro

    2014-01-01

    Introduction to the Green Syntheses SeriesPietro Tundo and John AndraosApplication of Material Efficiency Metrics to Assess Reaction Greenness-Illustrative Case Studies from Organic SynthesesJohn AndraosReaction 1: Synthesis of 3-Benzyl-5-Methyleneoxazolidin-2-one from N-Benzylprop-2-yn-1-Amine and CO2Qing-Wen Song and Liang-Nian HeReaction 2: Synthesis of the 5-Membered Cyclic Carbonates from Epoxides and CO2Qing-Wen Song, Liang-Nian HePart I: Green Methods for the Epoxidation of

  12. Aggressive HIV-1?

    OpenAIRE

    van der Hoek Lia; de Ronde Anthony; Berkhout Ben

    2005-01-01

    Abstract New York City health officials announced on February 11, 2005 that a patient rapidly developed full-blown AIDS shortly after being diagnosed with a rare, drug-resistant strain of HIV-1. The New York City Department of Health issued an alert to all hospitals and doctors and a press conference was held to announce the emergence of an aggressive HIV-1 strain that may be difficult to treat and that appears to trigger rapid progression to AIDS. Is the panic justified?

  13. On 1-qubit channels

    CERN Document Server

    Uhlmann, A

    2001-01-01

    The entropy H_T(rho) of a state rho with respect to a channel T and the Holevo capacity of the channel require the solution of difficult variational problems. For a class of 1-qubit channels, which contains all the extremal ones, the problem can be significantly simplified by associating an Hermitian antilinear operator theta to every channel of the considered class. The concurrence of the channel can be expressed by theta and turns out to be a flat roof. This allows to write down an explicit expression for H_T. Its maximum would give the Holevo (1-shot) capacity.

  14. Diabetes mellitus type 1

    OpenAIRE

    Tøraasen, Lisa Vangen; Al-Sultan, Zainab

    2014-01-01

    Hvert år blir rundt 600 nordmenn diagnostisert med sykdommen diabetes type 1, og Norge er et av landene i verden med størst andel av barnediabetes. I dag er det 15 000- 20 000 personer i Norge som har diabetes type 1, og antall barn som får diabetes har fordoblet seg de siste 30 årene (Diabetesforbundet, 2014). Problemstillingen vår gikk ut på hvordan sykepleiere kan veilede og undervise ungdom med nyoppdaget diabetes type på sykehus. Ut i fra litteraturstudiet har vi arbeidet oss frem for å ...

  15. Microelectronic systems 1 checkbook

    CERN Document Server

    Vears, R E

    2013-01-01

    Microelectronic Systems 1 Checkbook provides coverage of the Business and Technician Education Council level 1 unit in Microelectronic Systems. However, it can be regarded as a basic textbook in microelectronic systems for a much wider range of studies. Each topic considered in the text is presented in a way that assumes the reader has little prior knowledge of electronics. The aim of the book is to provide an introduction to the concept of systems, to differentiate analogue and digital systems, and to describe the nature of microprocessor-controlled systems. An introduction to programming is

  16. Opgavesamling Biokemi 1

    DEFF Research Database (Denmark)

    Bjergegaard, Charlotte

    Opgavesamling til bachelorkurset LKEB10077 Biokemi 1. Opgaverne er et supplement til forelæsninger og øvelser og har til formål at støtte op om indlæringen af biokemien. Der er inkluderet ret grundige løsninger til de enkelte opgaver.......Opgavesamling til bachelorkurset LKEB10077 Biokemi 1. Opgaverne er et supplement til forelæsninger og øvelser og har til formål at støtte op om indlæringen af biokemien. Der er inkluderet ret grundige løsninger til de enkelte opgaver....

  17. Sintesis Molibdenum Oksida Berpenyangga Silika sebagai Katalis pada Reaksi Oksidasi Etanol Menjadi Asetaldehida

    Directory of Open Access Journals (Sweden)

    Achyar Rasyidi

    2015-06-01

    Full Text Available Oksidasi etanol membentuk asetaldehida dengan menggunakan katalis molibdenum oksida berpenyangga silika oksida telah dilakukan. Preparasi katalis dilakukan dengan metode impregnasi dengan rasio Mo : Si 1 : 1, 3 : 1, 6 : 1, 9 : 1. Karakterisasi katalis dilakukan menggunakan X-Ray Difractometer (XRD. Hasil identifikasi menunjukkan bahwa komponen katalis yang telah dibuat mengandung kristal MoO3 dan SiO2. Uji kinerja katalis dilakukan terhadap reaksi oksidasi etanol menjadi asetaldehida. Reaksi oksidasi dilangsungkan dalam reaktor pipa lurus berunggun tetap yang beroperasi pada suhu 200oC, 225oC, 250oC, 275oC, 300oC, 325oC, dan 350oC pada tekanan atmosfir. Hasil uji kinerja menunjukkan bahwa konversi tertinggi diperoleh sebesar 91,99% pada temperatur 350oC menggunakan katalis dengan rasio Mo : Si = 9 : 1. Selektivitas tertinggi diperoleh sebesar 89,10% pada temperatur 200oC dengan rasio Mo : Si = 9 : 1. Yield tertinggi diperoleh sebesar 74,80% pada temperatur 350oC pada katalis dengan rasio Mo : Si = 9 : 1.

  18. Reference: RSEPVGRP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ter, domain A of the 35S promoter and the 35S^2 promoter. Transgenic Res 4:388-396 (1995) PubMed: 7581519; ... ...RSEPVGRP1 Elmayan T, Tepfer M Evaluation in tobacco of the organ specificity and strength of the rol D promo

  19. Code A1 Revised

    CERN Multimedia

    SC Secretariat

    2004-01-01

    Please note that the revised safety code A1 entitled 'MEDICAL CODE' is available on the web at the following url: https://edms.cern.ch/document/335476/last_released Paper copies can also be obtained from the SC Secretariat, e-mail : sc.secretariat@cern.ch SC Secretariat

  20. Main: MYCATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available is; NAC protein bound specifically to the CATGTG motif (Tran et al., 2004)); NAC protein bound specifically to the CA...MYCATERD1 S000413 29-November-2004 (last modified) kehi MYC recognition sequence (f...TGTG motif (Tran et al., 2004); water-stress; erd; Arabidopsis thaliana CATGTG ...

  1. Nordslesvigeren er nr. 1

    DEFF Research Database (Denmark)

    Christensen, Steffen Lind

    2015-01-01

    Historien om de nordslesvigske krigsdeltagere under 1. Verdenskrig er traditionelt blevet behandlet i et nationalt perspektiv. Her benævnes soldaterne oftest som ’danske’. Denne artikel undersøger, hvordan nordslesvigske soldater på Østfronten selv udtrykte deres identitet i krigssituationen...

  2. Reference: ABRELATERD1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ABRELATERD1 Nakashima K, Fujita Y, Katsura K, Maruyama K, Narusaka Y, Seki M, Shino...zaki K, Yamaguchi-Shinozaki K. Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, ger

  3. county_1m

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — This is a raster grid dataset (1-Meter Resolution) of the ground points derived from the acquired LiDAR. The Light Detection and Ranging (LiDAR) DEM dataset is a...

  4. Reference: ELRECOREPCRP1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ELRECOREPCRP1 Chen C, Chen Z Isolation and characterization of two pathogen- and sa...licylic acid-induced genes encoding WRKY DNA-binding proteins from tobacco Plant Mol Biol 42: 387-396 (2000) PubMed: 10794538; ...

  5. 1,3-Dinitrosoimidazolidine

    Directory of Open Access Journals (Sweden)

    Augusto Rivera

    2012-08-01

    Full Text Available The title compound, C3H6N4O2, exhibits partial disorder with the refined occupancy ratios of the two components being 0.582 (5:0.418 (5. In the major component, the nitroso groups have a relative syn spatial arrangement [O=N...N=O pseudo-torsion angle = 1.1 (4°], whereas the other component has an anti disposition [177.6 (1°]. The N—N=O moieties are almost coplanar with a dihedral angle of 5.3 (3°, while in the minor occupied set of atoms, this angle is 8 (1°. In both components, the imidazolidine ring adopts a twisted conformation on the C—C bond and the crystal structure shows the strain of this ring according to the N—CH2—CH2—N torsion angles [25.9 (5 and −23.8 (7°]. In the crystal, molecules are linked by weak C—H...O hydrogen bonds.

  6. Main: ABASEED1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ABASEED1 S000011 29-Sep-1999 (last modified) kehi ABA regulation; seed expression; ...Gene: carrot Dc3; Transacting factor: bZIP ?; Contains ACGT motif; Dc3; ABA; ABRE; bZIP; seed; ACGT; carrot (Daucus carota) TGTTACGTGCC ...

  7. Frameworks in CS1

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Caspersen, Michael Edelgaard

    2002-01-01

    In this paper we argue that introducing object-oriented frameworks as subject already in the CS1 curriculum is important if we are to train the programmers of tomorrow to become just as much software reusers as software producers. We present a simple, graphical, framework that we have successfully...

  8. Type 1 Diabetes Facts

    Science.gov (United States)

    ... levels 6 T1D is associated with an estimated loss of life-expectancy of up to 13 years 7 Warning ... urination Drowsiness or lethargy Increased appetite Sudden weight ... it’s difficult. It’s upsetting. It’s life threatening. It never goes away. But at the ...

  9. Reference: ARE1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ARE1 Rushmore TH, Morton MR, Pickett CB The antioxidant responsive element. Activat...ion by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266:11632-11639 (1991) PubMed: 1646813; ...

  10. Parcelhusatlas 1.0

    DEFF Research Database (Denmark)

    2016-01-01

    Parcelhusatlas 1.0 er et interaktivt GIS-kort i form af en web-app, der kan tilgås fra forskellige platforme. Kortet rummer data om Danmarks parcelhuse, aggregeret på sogneniveau. Referenceåret er 2013. Atlasset rummer forskellige temaer indenfor byggedata, socio-økonomiske data og energiforhold...

  11. 26 CFR 1.1201-1 - Alternative tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Alternative tax. 1.1201-1 Section 1.1201-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Wash Sales of Stock Or Securities § 1.1201-1 Alternative tax. (a) Corporations—(1)...

  12. 41 CFR 101-1.104-1 - Publication.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Publication. 101-1.104-1 Section 101-1.104-1 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System §...

  13. 26 CFR 1.815-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Taxable years affected. 1.815-1 Section 1.815-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Distributions to Shareholders § 1.815-1 Taxable years affected. Sections 1.815-2 through...

  14. 26 CFR 1.74-1 - Prizes and awards.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Prizes and awards. 1.74-1 Section 1.74-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Included in Gross Income § 1.74-1 Prizes and awards. (a) Inclusion in gross income. (1) Section...

  15. 2009 H1N1 Flu Vaccine Facts

    Science.gov (United States)

    ... page please turn Javascript on. Feature: Flu 2009 H1N1 Flu Vaccine Facts Past Issues / Fall 2009 Table ... of the H1N1 flu vaccine. 1 The 2009 H1N1 flu vaccine is safe and well tested. Clinical ...

  16. 26 CFR 1.85-1 - Unemployment compensation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Unemployment compensation. 1.85-1 Section 1.85-1...) INCOME TAXES (CONTINUED) Items Specifically Included in Gross Income § 1.85-1 Unemployment compensation... unemployment compensation (as defined in paragraph (b)(1) of this section) paid in taxable years...

  17. 26 CFR 1.1081-1 - Terms used.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Terms used. 1.1081-1 Section 1.1081-1 Internal... TAXES Exchanges in Obedience to S.e.c. Orders § 1.1081-1 Terms used. The following terms, when used in... or securities. Any other term used in this section and §§ 1.1081-2 to 1.1083-1, inclusive, which...

  18. Improving surface smoothness and photoluminescence of CdTe(1 1 1)A on Si(1 1 1) substrates grown by molecular beam epitaxy using Mn atoms

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jyh-Shyang, E-mail: jswang@cycu.edu.tw [Department of Physics, Chung Yuan Christian University, Chung-Li 32023, Taiwan (China); Center for Nano-Technology, Chung Yuan Christian University, Chung-Li 32023, Taiwan (China); Tsai, Yu-Hsuan; Chen, Chang-Wei; Dai, Zi-Yuan; Tong, Shih-Chang [Department of Physics, Chung Yuan Christian University, Chung-Li 32023, Taiwan (China); Yang, Chu-Shou [Graduate Institute of Electro-Optical Engineering, Tatung University, Taipei 10452, Taiwan (China); Wu, Chih-Hung [Institute of Nuclear Energy Research, Longtan 32546, Taiwan (China); Yuan, Chi-Tsu; Shen, Ji-Lin [Department of Physics, Chung Yuan Christian University, Chung-Li 32023, Taiwan (China); Center for Nano-Technology, Chung Yuan Christian University, Chung-Li 32023, Taiwan (China)

    2014-04-01

    Highlights: • CdTe(1 1 1)A epilayers were grown on Si(1 1 1) substrates by molecular beam epitaxy. • We report an enhanced growth using Mn atoms. • The significant improvements in surface quality and optical properties were found. - Abstract: This work demonstrates an improvement of the molecular beam epitaxial growth of CdTe(1 1 1)A epilayer on Si(1 1 1) substrates using Mn atoms. The reflection high-energy electron diffraction patterns show that the involvement of some Mn atoms in the growth of CdTe(1 1 1)A is even more effective than the use of a buffer layer with a smooth surface for forming good CdTe(1 1 1)A epilayers. 10 K Photoluminescence spectra show that the incorporation of only 2% Mn significantly reduced the intensity of defect-related emissions and considerably increased the integral intensity of exciton-related emissions by a large factor of about 400.

  19. Crystalline 1H-1,2,3-triazol-5-ylidenes

    Energy Technology Data Exchange (ETDEWEB)

    Bertrand, Guy; Gulsado-Barrios, Gregorio; Bouffard, Jean; Donnadieu, Bruno

    2016-08-02

    The present invention provides novel and stable crystalline 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes. The present invention also provides methods of making 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes. The present invention also provides methods of using 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes in catalytic reactions.

  20. Heat Roadmap Europe 1

    DEFF Research Database (Denmark)

    Connolly, David; Mathiesen, Brian Vad; Østergaard, Poul Alberg;

    2012-01-01

    Heat Roadmap Europe (Pre-study 1) investigates the role of district heating in the EU27 energy system by mapping local conditions across Europe, identifying the potential for district heating expansion, and subsequently simulating the potential resource in an hourly model of the EU27 energy system....... In 2010, approximately 12% of the space heating demand in Europe is met by district heating, but in this study four alternative scenarios are considered for the EU27 energy system: 1. 2010 with 30% district heating 2. 2010 with 50% district heating 3. 2030 with 30% district heating 4. 2050 with 50......% district heating These scenarios are investigated in two steps. Firstly, district heating replaces individual boilers by converting condensing power plants to combined heat and power plants (CHP) to illustrate how district heating improves the overall efficiency of the energy system. In the second step...

  1. Summary: after LS1

    International Nuclear Information System (INIS)

    After LS1 the energy will be about 6.5 TeV. The physics potential of LHC is determined by the integrated luminosity useful for the experiments and not only by the peak luminosity. The integrated luminosity is determined by the peak luminosity, the luminosity decay and the efficiency of operation (availability). In this session two of these parameters are addressed, the peak luminosity and the availability. In this paper peak luminosity is discussed through the performance potential of the injectors and through the global performance reach of LHC after LS1. LHC availability is tackled through the issues of the reliability of the magnet powering and of the beam system and of the occurrence of quenches

  2. NZMATH 1.0

    CERN Document Server

    Tanaka, Satoru; Nakamula, Ken; Matsui, Tetsushi; Uchiyama, Shigenori

    2010-01-01

    This is an announcement of the first official release ver.1.0 of a Python system NZMATH for number theory. We overview all functions in NZMATH 1.0, show main properties after former report on NZMATH 0.5.0, and describe new features for stable development. The most important point of the release is that we can now treat number fields. The second big change is that new type of polynomial programs are provided. Elliptic curve primality proving and its related programs are also available, where we partly use a library outside NZMATH as an advantage of writing the system only by Python. On method of development, a new feature is that NZMATH is registered on SourceForge as an open source project to keep continuous development of the project. This is a unique attempt among existing systems for number theory.

  3. Ferrocene-1-carbaldehyde thiosemicarbazone

    Directory of Open Access Journals (Sweden)

    M. R. Vikneswaran

    2010-06-01

    Full Text Available The asymmetric unit of the title compound, [Fe(C5H5(C7H8N3S], consists of two crystallographically independent molecules, A and B. The cyclopentadienyl (Cp rings in both molecules adopt an eclipsed conformation and are parallel to each other, forming dihedral angles of 2.5 (3 and 1.1 (3°, respectively. The mean plane of the semicarbazone group is coplanar with the attached Cp ring in molecule A, whereas it is twisted away in molecule B. In the crystal structure, intermolecular N—H...S hydrogen bonds link the molecules into two-dimensional planes parallel to the ab plane. The structure is further consolidated by C—H...π interactions.

  4. Evaluation report no.1

    International Nuclear Information System (INIS)

    This document, which is the first evaluation report from the French National Evaluation Commission about research on radioactive waste management, was sent to the French Government on June 30, 1995. The Commission was created in January 1994 and started its investigations on April 1994. The evaluation concerns the three axes of the 91-1381 law from December 30, 1991 (1 - separation-transmutation and minimization of wastes, 2 - underground disposal, 3 - choices for conditioning, storage and disposal). The document has been written after hearing of the principal French research organisms. The report focusses on the necessity for a scientific and technical coordination between all the organisms concerned, for a consistent and open analysis of all research topics. This implies a compatibility between schedules and specifications, and with the 15 years allowed by the law. (J.S.). 15 figs., 14 tabs., 4 annexes., 1 glossary

  5. Physics. Module 1. Mechanics

    OpenAIRE

    Бовтрук, Алла Георгіївна; Мєняйлов, Сергій Миколайович; Максимов, Сергій Леонідович; Поліщук, Аркадій Петрович

    2009-01-01

    Ukraine’s joining Bologna process requires creating new books in physics (in English in particular). The book is developed for all forms of studying physics on the Credit-based Modular System basis in higher school. «Physics. Module 1. Mechanics» presents Newtonian mechanics and Special theory of relativity. It contains eight Study Units which include theoretical information, test questions, sample problems, laboratory works and individual home tasks. It is designed for students of engi...

  6. Main: CCAATBOX1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available 5'-non-coding regions of eukaryotic genes; CCAAT box found in the promoter of heat shock protein genes; Loca...CCAATBOX1 S000030 04-January-2007 (last modified) kehi Common sequence found in the...ted immediately upstream from the most distal HSE of the promoter; CCAAT box act cooperatively with HSEs to... increase the hs promoter activity; HSE (Heat shock element); CCAAT box; eukaryotes; Glycine max (Soybean) CCAAT ...

  7. Main: AACACOREOSGLUB1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AACACOREOSGLUB1 S000353 16-Feb-2001 (last modified) seki Core of AACA motifs found ...in rice (O.s.) glutelin genes, involved in controlling the endosperm-specific expression; AACA is also close...m-specific enhancement to the truncated -90 CaMV 35S promoter; See also S000045, ...S000181, S000276; glutelin; AACA; GCN4; seed; endosperm; rice (Oryza sativa) AACAAAC ...

  8. PETROLOGY (1)IGNEOUS PETROLOGY

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>20082204 Cong Feng(Institute of Geochem- istry,Chinese Academy of Sciences,Guiyang 550002,China);Tang Hongfeng Geochem- istry and Tectonic Setting of Devonian Rhyo- lites in Southern Altay,Xinjiang,Northwest China(Geotectonica et Metallogenia,ISSN 1001—1552,CN44—1595/P,31(3),2007, p.359—364,6 illus.,1 table,17 refs.) Key words:rhyolites,Altai Mountains

  9. Chapter 1: Introduction

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-01-18

    The Office of Energy Efficiency and Renewable Energy (EERE) develops–and encourages consumers and business to adopt–technologies that improve energy efficiency and increase the use of renewable energy. This report describes analysis undertaken by EERE to better understand the extent to which the technologies and market improvements funded by its FY 2004 Budget Request1 will make energy more affordable, cleaner, and more reliable.

  10. UOA1: Hardware Manual

    Energy Technology Data Exchange (ETDEWEB)

    Wolfers, G.; Sanchez, E.

    2012-07-01

    The UOA1 is a versatile printed circuit board which can be configured to accommodate up to four analogue signal channels of either electrical to optical or optical to electrical converters. A charge-balance voltage to frequency technique is used for the conversion. The board can be adapted to different electrical input or output range and the full scale frequency can be adjusted to provide the best accuracy-to bandwidth compromise for each application. (Author)

  11. Euroconstruction Report 1

    OpenAIRE

    Gunnigan, Louis; ORR, TREVOR

    1998-01-01

    This report was prepared on behalf of the Construction Industry Federation as Ireland’s initial contribution to the Leonardo da Vinci Project: Euroconstruction. The report is divided into 3 sections. Section 1 concentrates on the recent and likely future changes in the structure of the Irish construction market and the impact of these changes on project management and project financing. The recent growth of the industry is documented and predictions for the future of the industry in Ire...

  12. Main: POLASIG1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available POLASIG1 S000080 18-November-2005 (last modified) kehi PolyA signal; poly A signal ...found in legA gene of pea, rice alpha-amylase; -10 to -30 in the case of animal genes. Near upstream elements (NUE) in Arabidopsi...s (Loke et al. 2005); poly A signal; NUE; FUE; pea (Pisum sativum); rice (Oryza sativa); Arabidopsis thaliana; AATAAA ...

  13. Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives

    OpenAIRE

    Vepsäläinen Jouko J; Turhanen Petri A

    2006-01-01

    Abstract A novel strategy for the synthesis of (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives (1a-d) via (1-hydroxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives (2a-d), starting from alendronate has been developed with reasonable 51–77% overall yields. Intermediate products, (1-hydroxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives (2a-d), were prepared in water with reasonable to high yields (52–94%).

  14. Indico 1.0

    CERN Document Server

    Lopez, J B Gonzalez; Baron, T; Ferreira, P; Kolobara, B; Pugh, M A; Resco, A; Trzaskoma, J P

    2014-01-01

    Indico has evolved into the main event organization software, room booking tool and collaboration hub for CERN. The growth in its usage has only accelerated during the past 9 years, and today Indico holds more that 215,000 events and 1,100,000 files. The growth was also substantial in terms of functionalities and improvements. In the last year alone, Indico has matured considerably in 3 key areas: enhanced usability, optimized performance and additional features, especially those related to meeting collaboration. Along the course of 2012, much activity has centred around consolidating all this effort and investment into 'version 1.0', recently released in 2013.Version 1.0 brings along new features, such as the Microsoft Exchange calendar synchronization for participants, many new and clean interfaces (badges and poster generation, list of contributions, abstracts, etc) and so forth. But most importantly, it brings a message: Indico is now stable, consolidated and mature after more than 10 years of non-stop de...

  15. Indico 1.0

    Science.gov (United States)

    Gonzalez Lopez, J. B.; Avilés, A.; Baron, T.; Ferreira, P.; Kolobara, B.; Pugh, M. A.; Resco, A.; Trzaskoma, J. P.

    2014-06-01

    Indico has evolved into the main event organization software, room booking tool and collaboration hub for CERN. The growth in its usage has only accelerated during the past 9 years, and today Indico holds more that 215,000 events and 1,100,000 files. The growth was also substantial in terms of functionalities and improvements. In the last year alone, Indico has matured considerably in 3 key areas: enhanced usability, optimized performance and additional features, especially those related to meeting collaboration. Along the course of 2012, much activity has centred around consolidating all this effort and investment into "version 1.0", recently released in 2013.Version 1.0 brings along new features, such as the Microsoft Exchange calendar synchronization for participants, many new and clean interfaces (badges and poster generation, list of contributions, abstracts, etc) and so forth. But most importantly, it brings a message: Indico is now stable, consolidated and mature after more than 10 years of non-stop development. This message is addressed not only to CERN users but also to the many organisations, in or outside HEP, which have already installed the software, and to others who might soon join this community. In this document, we describe the current state of the art of Indico, and how it was built. This does not mean that the Indico software is complete, far from it! We have plenty of new ideas and projects that we are working on and which we have shared during CHEP 2013.

  16. AMF 1 Site Science

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Mark Alan [Rutgers Univ., New Brunswick, NJ (United States)

    2016-08-18

    This report documents progress on DOE Grant# DE-FG02-08ER64531 funded by the Department of Energy’s Atmospheric Systems Research (ASR) program covering the period between its inception in 2008 and its conclusion in 2014. The Atmospheric Radiation Measurement (ARM) Program’s Mobile Facility #1 (AMF#1) is a collection of state-of-the art atmospheric sensing systems including remote and in situ instrumentation designed to characterize the atmospheric column above and in the immediate vicinity of the deployment location. The grant discussed in this report funded the activities of the AMF#1 Site Scientist Team. Broad responsibilities of this team included examining new deployment sites and recommending instrument deployment configurations; data quality control during the early stages of deployments and for certain instruments through the course of the deployment; scientific outreach in the host country or location (particularly international deployments); scientific research oriented toward basic questions about cloud physics and radiation transfer in the deployment region; and training of Ph.D. students to conduct future research relevant to the Atmospheric Systems Research (ASR) program.

  17. Point 1 Updates

    CERN Multimedia

    Inigo-Golfin, J.

    The ATLAS experimental area is located in Point 1, just across the main CERN entrance, in the commune of Meyrin. There people are ever so busy to finish the different infrastructures for ATLAS. Not only has Civil Engineering finished the construction of the USA15 technical cavern, but the excavation of the main UX15 cavern has resumed below the machine tunnel, after a brief halt to allow the construction of the UJ-caverns for the power converters of the LHC machine. The excavation work should end in August 2002. The UX15 hand-over to ATLAS is expected in April 2003. On the surface civil engineering is starting to complete the last two surface buildings (SDX1 and SH1), once the services (cooling pipes, ventilation ducts and the largest item, the lift modules and its lift of course) in the shaft PX15 have been completed. But the civil engineering is not all. A lot more is under way. The site installation of the steel structures in the caverns is to begin in Autumn, along with all the cooling pipes, airconditi...

  18. Main: 1U1H [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1U1H シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. 5-Methyltetrahydropteroyl...ITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK arabi_1U1H.jpg ...

  19. Main: 1H1Y [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1H1Y イネ Rice Oryza sativa L. D-Ribulose-5-Phosphate 3-Epimerase Oryza Sativa Molecu...V. 326 127 2003 3-Epimerase, Oxidative Pentose Phosphate Pathway, Isomerase SWS:Q9SE42,Q9SE42|EMBL; AF189365; AAF01048.1; -.|PDB; 1H...1Y; X-ray; A/B=1-228.|PDB; 1H1Z; X-ray; A/B=1-228.|Gramene; Q9SE42; -.|GO; GO:001685...ELIQSIKAKGMRPGVSLRPGTPVEEVFPLVEAENPVELVLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAGSSIFGAAEPGEVISALRKSVEGSQNKS rice_1H1Y.jpg ...

  20. Main: 1H1Z [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1H1Z イネ Rice Oryza sativa L. D-Ribulose-5-Phosphate 3-Epimerase Oryza Sativa Molecu...V. 326 127 2003 3-Epimerase, Oxidative Pentose Phosphate Pathway, Isomerase SWS:Q9SE42,Q9SE42|EMBL; AF189365; AAF01048.1; -.|PDB; 1H...1Y; X-ray; A/B=1-228.|PDB; 1H1Z; X-ray; A/B=1-228.|Gramene; Q9SE42; -.|GO; GO:001685...ELIQSIKAKGMRPGVSLRPGTPVEEVFPLVEAENPVELVLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAGSSIFGAAEPGEVISALRKSVEGSQNKS rice_1H1Z.jpg ...

  1. Analysis list: Whsc1l1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Whsc1l1 Blood + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Whsc1l1.1....tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Whsc1l1.5.tsv http://dbarchive.biosciencedbc.jp/k...yushu-u/mm9/target/Whsc1l1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Whsc1l1.Blood.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Blood.gml ...

  2. Intestinal and Hepatic Niemann-Pick C1-Like 1

    OpenAIRE

    Sung-Woo Park

    2013-01-01

    Polytopic transmembrane protein, Niemann-Pick C1-Like 1 (NPC1L1) is localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It mediates intestinal cholesterol absorption and prevents extensive loss of cholesterol by transporting biliary cholesterol into hepatocytes. NPC1L1 is a molecular target of ezetimibe, an agent for hypercholesterolemia. Recently, NPC1L1 inhibition has been shown to prevent metabolic disorders such as fatty liver disease, obesity, dia...

  3. Universal graphs at $\\aleph_{\\omega_1+1}$

    OpenAIRE

    Davis, Jacob

    2016-01-01

    Starting from a supercompact cardinal we build a model in which $2^{\\aleph_{\\omega_1}}=2^{\\aleph_{\\omega_1+1}}=\\aleph_{\\omega_1+3}$ but there is a jointly universal family of size $\\aleph_{\\omega_1+2}$ of graphs on $\\aleph_{\\omega_1+1}$. The same technique will work for any uncountable cardinal in place of $\\omega_1$.

  4. Survey of ortho-H2D+(1_{1,0}-1_{1,1}) in dense cloud cores

    CERN Document Server

    Caselli, Paola; Ceccarelli, Cecilia; van der Tak, Floris; Crapsi, Antonio; Bacmann, Aurore

    2008-01-01

    We present a survey of the ortho-H2D+(1_{1,0}-1_{1,1}) line toward a sample of 10 starless cores and 6 protostellar cores, carried out at the Caltech Submillimeter Observatory. The high diagnostic power of this line is revealed for the study of the chemistry, and the evolutionary and dynamical status of low-mass dense cores. The line is detected in 7 starless cores and in 4 protostellar cores. N(ortho-H2D+) ranges between 2 and 40x10^{12} cm^{-2} in starless cores and between 2 and 9x10^{12} cm^{-2} in protostellar cores. The brightest lines are detected toward the densest and most centrally concentrated starless cores, where the CO depletion factor and the deuterium fractionation are also largest. The large scatter observed in plots of N(ortho-H2D+) vs. the observed deuterium fractionation and vs. the CO depletion factor is likely to be due to variations in the ortho-to-para (o/p) ratio of H2D+ from >0.5 for T_{kin} < 10 K gas in pre-stellar cores to ~0.03 (consistent with T_{kin} ~15 K for protostellar c...

  5. 26 CFR 1.149(g)-1 - Hedge bonds.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Hedge bonds. 1.149(g)-1 Section 1.149(g)-1...) INCOME TAXES (CONTINUED) Tax Exemption Requirements for State and Local Bonds § 1.149(g)-1 Hedge bonds... of replacement proceeds (other than amounts in a bona fide debt service fund or a reasonably...

  6. 26 CFR 1.1464-1 - Refunds or credits.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Refunds or credits. 1.1464-1 Section 1.1464-1...) INCOME TAXES Application of Withholding Provisions § 1.1464-1 Refunds or credits. (a) In general. The refund or credit under chapter 65 of the Code of an overpayment of tax which has actually been...

  7. 26 CFR 1.803-1 - Life insurance reserves.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Life insurance reserves. 1.803-1 Section 1.803-1...) INCOME TAXES Life Insurance Companies § 1.803-1 Life insurance reserves. (a) The term “life insurance... covered by the premiums are not included in life insurance reserves. Unpaid loss reserves...

  8. Quantum Analogs of Tensor Product Representations of su(1; 1)*

    NARCIS (Netherlands)

    Groenevelt, W.

    2011-01-01

    Abstract. We study representations of Uq(su(1; 1)) that can be considered as quantum analogs of tensor products of irreducible -representations of the Lie algebra su(1; 1). We determine the decomposition of these representations into irreducible -representations of Uq(su(1; 1)) by diagonalizing the

  9. 26 CFR 1.531-1 - Imposition of tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Imposition of tax. 1.531-1 Section 1.531-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.531-1 Imposition...

  10. 26 CFR 1.536-1 - Short taxable years.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Short taxable years. 1.536-1 Section 1.536-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.536-1 Short...

  11. 26 CFR 1.282-1.300 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false 1.282-1.300 Section 1.282-1.300 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Terminal Railroad Corporations and Their Shareholders §§ 1.282-1.300...

  12. 26 CFR 1.346-1 - Partial liquidation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Partial liquidation. 1.346-1 Section 1.346-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Definition § 1.346-1 Partial liquidation. (a) General. This section defines a...

  13. 26 CFR 1.62-1 - Adjusted gross income.

    Science.gov (United States)

    2010-04-01

    ... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Definition of Gross Income, Adjusted Gross Income, and Taxable Income § 1.62-1... 26 CFR part 1 (§§ 1.61 to 1.169) revised April 1, 1992). (d)-(h) (i) Effective date. Paragraph (c)...

  14. 26 CFR 1.514(e)-1 - Allocation rules.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Allocation rules. 1.514(e)-1 Section 1.514(e)-1... Allocation rules. Where only a portion of property is debt-financed property, proper allocation of the basis...)(iii) of § 1.514(b)-1 for illustrations of proper allocation....

  15. 26 CFR 1.708-1 - Continuation of partnership.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Continuation of partnership. 1.708-1 Section 1... (CONTINUED) INCOME TAXES Partners and Partnerships § 1.708-1 Continuation of partnership. (a) General rule. For purposes of subchapter K, chapter 1 of the Code, an existing partnership shall be considered...

  16. 26 CFR 1.471-1 - Need for inventories.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Need for inventories. 1.471-1 Section 1.471-1...) INCOME TAXES Inventories § 1.471-1 Need for inventories. In order to reflect taxable income correctly, inventories at the beginning and end of each taxable year are necessary in every case in which the...

  17. Cdk1 and SUMO regulate Swe1 stability.

    Directory of Open Access Journals (Sweden)

    Kobi J Simpson-Lavy

    Full Text Available The Swe1/Wee1 kinase phosphorylates and inhibits Cdk1-Clb2 and is a major mitotic switch. Swe1 levels are controlled by ubiquitin mediated degradation, which is regulated by interactions with various mitotic kinases. We have recently reported that Swe1 levels are capable of sensing the progress of the cell cycle by measuring the levels of Cdk1-Clb2, Cdc5 and Hsl1. We report here a novel mechanism that regulates the levels of Swe1. We show that S. cerevisiae Swe1 is modified by Smt3/SUMO on residue K594 in a Cdk1 dependant manner. A degradation of the swe1(K594R mutant that cannot be modified by Smt3 is considerably delayed in comparison to wild type Swe1. Swe1(K594R cells express elevated levels of Swe1 protein and demonstrate higher levels of Swe1 activity as manifested by Cdk1-Y19 phosphorylation. Interestingly this mutant is not targeted, like wild type Swe1, to the bud neck where Swe1 degradation takes place. We show that Swe1 is SUMOylated by the Siz1 SUMO ligase, and consequently siz1Δ cells express elevated levels of Swe1 protein and activity. Finally we show that swe1(K594R cells are sensitive to osmotic stress, which is in line with their compromised regulation of Swe1 degradation.

  18. 26 CFR 1.509(d)-1 - Definition of support

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition of support 1.509(d)-1 Section 1.509(d)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(d)-1 Definition of support For purposes...

  19. 26 CFR 1.1493-1 - Definition of foreign trust.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Definition of foreign trust. 1.1493-1 Section 1... (CONTINUED) INCOME TAXES Tax on Transfers to Avoid Income Tax § 1.1493-1 Definition of foreign trust. For taxable years beginning before January 1, 1967, a trust is to be considered a “foreign trust” within...

  20. 26 CFR 1.584-1 - Common trust funds.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Common trust funds. 1.584-1 Section 1.584-1...) INCOME TAXES (CONTINUED) Banking Institutions § 1.584-1 Common trust funds. (a) Method of taxation. A common trust fund maintained by a bank is not subject to taxation under this chapter and is...

  1. 26 CFR 1.1002-1 - Sales or exchanges.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Sales or exchanges. 1.1002-1 Section 1.1002-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Determination of Amount of and Recognition of Gain Or Loss § 1.1002-1 Sales or exchanges....

  2. 26 CFR 1.737-1 - Recognition of precontribution gain.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Recognition of precontribution gain. 1.737-1 Section 1.737-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Distributions by A Partnership § 1.737-1 Recognition of...

  3. 26 CFR 1.171-1 - Bond premium.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Bond premium. 1.171-1 Section 1.171-1 Internal... TAXES Itemized Deductions for Individuals and Corporations (continued) § 1.171-1 Bond premium. (a... and amortization of bond premium by a holder. In general, a holder amortizes bond premium...

  4. VENESAT-1 Successfully Launched

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Venezuelan first satellite VENESAT-1 (or Simon Bolivar) was sent to space from the Xichang Satellite Launch Center(XSLC) at 0:53 (Beijing time) on October 30 atop a LM-3B launch vehicle. About 12 minutes later, the satellite entered the preset GTO orbit at the altitude of 36,000km. After four maneuvers, the satellite was normally positioned at 78 degrees west longitude at 15:39 (Beijing time) on November 9,beaming the majority of Latin America and part of the Caribbean region.

  5. Nonlocal N=1 Supersymmetry

    CERN Document Server

    Kimura, Tetsuji; Noumi, Toshifumi; Yamaguchi, Masahide

    2016-01-01

    We construct $\\mathcal{N}=1$ supersymmetric nonlocal theories in four dimension. We discuss higher derivative extensions of chiral and vector superfields, and write down generic forms of K\\"ahler potential and superpotential up to quadratic order. We derive the condition in which an auxiliary field remains non-dynamical, and the dynamical scalars and fermions are free from the ghost degrees of freedom. We also investigate the nonlocal effects on the supersymmetry breaking and find that supertrace (mass) formula is significantly modified even at the tree level.

  6. Nuflood, Version 1.x

    Energy Technology Data Exchange (ETDEWEB)

    2016-07-29

    NUFLOOD Version 1.x is a surface-water hydrodynamic package designed for the simulation of overland flow of fluids. It consists of various routines to address a wide range of applications (e.g., rainfall-runoff, tsunami, storm surge) and real time, interactive visualization tools. NUFLOOD has been designed for general-purpose computers and workstations containing multi-core processors and/or graphics processing units. The software is easy to use and extensible, constructed in mind for instructors, students, and practicing engineers. NUFLOOD is intended to assist the water resource community in planning against water-related natural disasters.

  7. Characterisation of polymers, 1

    CERN Document Server

    Crompton, Roy

    2008-01-01

    This essential guide to Polymer Characterisation is a complete compendium of methodologies that have evolved for the determination of the chemical composition of polymers. This 478-page book gives an up-to-date and thorough exposition of the state-of-the-art theories and availability of instrumentation needed to effect chemical and physical analysis of polymers. This is supported by approximately 1200 references. Volume 1 covers the methodology used for the determination of metals, non-metals and organic functional groups in polymers, and for the determination of the ratio in which different m

  8. B1 Aerogels

    DEFF Research Database (Denmark)

    Duer, Karsten; Svendsen, Sv Aa Højgaard

    1996-01-01

    DGU that was developped during the project. B12 and B14 have measured the g-value and the U-value respectively of the aerogel DGU.Furthermore calculations of the energy saving potential by using aerogel windows in selected residential and commercial buildings under different climatic conditions were...... carried out as part of the A2/A3 project.The B1 Aerogel project has been carried out with partition of the following nations: Denmark, Finland, France, Germany, Japan, Norway, Sweden and the United Kingdom....

  9. Brownian Brownian Motion-1

    OpenAIRE

    Chernov, N.; Dolgopyat, D.

    2008-01-01

    A classical model of Brownian motion consists of a heavy molecule submerged into a gas of light atoms in a closed container. In this work we study a 2D version of this model, where the molecule is a heavy disk of mass M and the gas is represented by just one point particle of mass m = 1, which interacts with the disk and the walls of the container via elastic collisions. Chaotic behavior of the particles is ensured by convex (scattering) walls of the container. We prove that the position and ...

  10. Chandrayaan-1: Science goals

    Indian Academy of Sciences (India)

    N Bhandari

    2005-12-01

    The primary objectives of the Chandrayaan-1 mission are simultaneous chemical,mineralogical and topographic mapping of the lunar surface at high spatial resolution.These data should enable us to understand compositional variation of major elements,which in turn,should lead to a better understanding of the stratigraphic relationships between various litho units occurring on the lunar surface.The major element distribution will be determined using an X-ray fluorescence spectrometer (LEX),sensitive in the energy range of 1 –10 keV where Mg,Al,Si,Ca and Fe give their K lines.A solar X-ray monitor (SXM)to measure the energy spectrum of solar X-rays,which are responsible for the fluorescent X-rays,is included.Radioactive elements like Th will be measured by its 238.6 keV line using a low energy gamma-ray spectrometer (HEX)operating in the 20 –250 keV region.The mineral composition will be determined by a hyper-spectral imaging spectrometer (HySI)sensitive in the 400 –920 nm range.The wavelength range is further extended to 2600 nm where some spectral features of the abundant lunar minerals and water occur,by using a near-infrared spectrometer (SIR-2),similar to that used on the Smart-1 mission,in collaboration with ESA.A terrain mapping camera (TMC)in the panchromatic band will provide a three-dimensional map of the lunar surface with a spatial resolution of about 5 m.Aided by a laser altimeter (LLRI) to determine the altitude of the lunar craft,to correct for spatial coverage by various instruments, TMC should enable us to prepare an elevation map with an accuracy of about 10 m. Four additional instruments under international collaboration are being considered.These are: a Miniature Imaging Radar Instrument (mini-SAR),Sub Atomic Re flecting Analyser (SARA), the Moon Mineral Mapper (M3)and a Radiation Monitor (RADOM).Apart from these scientific payloads,certain technology experiments have been proposed,which may include an impactor which will be released to

  11. R806 (part 1)

    CERN Multimedia

    1976-01-01

    R806 was designed by the BNL-CERN-Syracuse-Yale Collaboration (Bill Willis spokesman) to study large transverse momentum phenomena, and installed in intersection 8 of the ISR. The main detectors were Lithium foil transition radiation detectors to identify electrons and liquid argon calorimeters to measure the energy of the electrons and photons (among the first such calorimeters to be used in an experiment). In part 1 there were two modules, top and bottom of the horizontal beam pipe; the black vertical pipe contains the cryogenics (LN2 and Lar) and is connected to the two modules with the horizontal piping.

  12. ISR Intersection 1

    CERN Multimedia

    1974-01-01

    The experimental apparatus used at intersection 1 by the CERN-Bologna Collaboration (experiment R105). It consists of two almost identical magnetic spectrometers centered at 90 degrees on opposite sides of the intersection region. In each spectrometer one can see magnetostrictive wire spark chambers, a magnet, more chambers and various hodoscopes of scintillation counters. Gas Cerenkov counters (almost invisible in the picture) are located in the gap of each magnet. On the left hand side, a matrix of 119 lead glass Cerenkov counters is located behind some concrete and iron shielding.

  13. Mosaic neurofibromatosis type 1.

    Science.gov (United States)

    Liang, Christine; Schaffer, Julie V

    2008-01-01

    A 24-year-old man presented with numerous lentigines and multiple cafe-au-lait macules on both sides of the face, neck, and trunk as well as on the proximal area of the upper extremities and in the axillae. The pigmented lesions had a Blaschko-linear distribution on the upper trunk and were limited to the left side of the abdomen, with a sharp demarcation at the midline. Multiple, cutaneous neurofibromas were found on the trunk, and ophthalmologic examination showed a Lisch nodule in the left iris. The clinical findings and their widespread but segmental distribution were consistent with a diagnosis of mosaic neurofibromatosis type 1. PMID:18627742

  14. On 1-qubit channels

    OpenAIRE

    Uhlmann, Armin

    2000-01-01

    The entropy H_T(rho) of a state rho with respect to a channel T and the Holevo capacity of the channel require the solution of difficult variational problems. For a class of 1-qubit channels, which contains all the extremal ones, the problem can be significantly simplified by associating an Hermitian antilinear operator theta to every channel of the considered class. The concurrence of the channel can be expressed by theta and turns out to be a flat roof. This allows to write down an explicit...

  15. Diabetes Mellitus Type 1

    OpenAIRE

    Trydal, Kari

    2015-01-01

    Hvert år får rundt 300 barn og 600 voksne diabetes mellitus type 1, og til sammen har rundt 28 000 personer denne sykdommen i Norge i dag. Det er en kronisk metabolsk sykdom, med en absolutt insulinmangel. Gjennom litteratur og forskning er det vist, at for å forebygge senkomplikasjoner, trenger pasienten informasjon, undervisning og praktisk veiledning når det gjelder medisinering, kosthold og fysisk aktivitet, og motivering til å mestre sykdommen. I praksis vil sykepleier spille en aktiv ro...

  16. Annexe 1. Figures

    OpenAIRE

    2014-01-01

    Figure 1. — Carte générale de Colombie Figure 2. — Le Nouveau Royaume de Grenade Figure 3. — Nouvelle Grenade — Région centre Figure 4. — Nouvelle Grenade — Région nord Figure 5. — Nouvelle Grenade — Région sud-ouest Figure 6. — Schéma-organigramme des relations établies entre les institutions chargées de l’implantation de la foi dans le Nouveau Monde, (tiré de Enrique Düssel, Historia de la Iglesia en América Latina, Bogotá, Universidad Santo Tomás, 1984, p. 89)....

  17. H1N1: pandemia e perspectiva atual H1N1: overview and perspectives

    Directory of Open Access Journals (Sweden)

    Nancy Bellei

    2011-12-01

    Full Text Available O vírus influenza de origem suína, A/California/04/2009 (H1N1, foi inicialmente detectado no México e determinou a pandemia de influenza de 2009. Em agosto de 2010, a Organização Mundial da Saúde (OMS declarou o início da fase pós-pandêmica. As características dessa última pandemia foram marcadamente diferentes das anteriores. O vírus emergiu de rearranjos genéticos originários em hospedeiro mamífero não humano, demonstrou transmissibilidade interespécies e afetou a população humana de forma diferente dos vírus pandêmicos anteriores (1918, 1957 e 1968 com maior morbidade e mortalidade em crianças e adultos jovens. Atualmente, o vírus apresenta padrão sazonal da mesma forma que o influenza A H3N2 e o influenza B, mantendo, até o momento, o mesmo perfil de patogenicidade, espectro clínico e sensibilidade a antivirais. A cepa foi incluída na vacina sazonal trivalente anual recomendada, principalmente para proteção dos grupos de risco mais vulneráveis a complicações pelas diferentes cepas de influenza.The swine origin influenza virus A/CALIFORNIA/04/2009 (H1N1 was first detected in Mexico and determined the 2009 influenza pandemic. In August 2010, World Health Organization (WHO declared the beginning of the post-pandemic period. This last pandemic was distinctly different from previous ones. The virus emerged from genetic rearrangement in non-human mammalian host. Moreover, its inter-species transmission is fully reported. However, it affected human population differently from previous pandemic viruses (1918, 1957, 1968, with increased morbidity and mortality among children and young adults. Currently, the virus has a seasonal pattern in the same way as influenza A H3N2 and influenza B, maintaining the same pathogenicity profile, clinical spectrum and sensitivity to antiviral agents. The strain was included in the annual trivalent seasonal vaccine formulation, mainly for risk groups, which are more vulnerable to

  18. 78 FR 79007 - 1,1,1,2-Tetrafluoroethane From China

    Science.gov (United States)

    2013-12-27

    ... the notice in the Federal Register of October 28, 2013 (78 FR 64243). The conference was held in... COMMISSION 1,1,1,2-Tetrafluoroethane From China Determinations On the basis of the record \\1\\ developed in... reason of imports from China of 1,1,1,2- Tetrafluoroethane, provided for in subheadings 2903.39.20 of...

  19. Regional gene expression of LOX-1, VCAM-1, and ICAM-1 in aorta of HIV-1 transgenic rats

    DEFF Research Database (Denmark)

    Hag, Anne Mette Fisker; Kristoffersen, Ulrik Sloth; Pedersen, Sune Folke;

    2009-01-01

    endpoints, studies in animal models could be attractive alternatives. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated gene expression of lectin-like oxidized-low-density-lipoprotein receptor-1 (LOX-1), vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) in HIV-1...... transgenic (HIV-1Tg) rats; these genes are all thought to play important roles in early atherogenesis. Furthermore, the plasma level of sICAM-1 was measured. We found that gene expressions of LOX-1 and VCAM-1 were higher in the aortic arch of HIV-1Tg rats compared to controls. Also, the level of sICAM-1...... was elevated in the HIV-1Tg rats compared to controls, but the ICAM-1 gene expression profile did not show any differences between the groups. CONCLUSIONS/SIGNIFICANCE: HIV-1Tg rats have gene expression patterns indicating endothelial dysfunction and accelerated atherosclerosis in aorta, suggesting that HIV...

  20. Main: P1BS [PLACE

    Lifescience Database Archive (English)

    Full Text Available upstream regions of phosphate starvation responsive genes from several plant species; phr1 (phosphate starvation response 1) gene cod...es for PHR1 protein related to PSR1 gene in C. reinhardtii; phosphate; starvation;

  1. The 2009 H1N1 Pandemic Influenza in Korea

    OpenAIRE

    Kim, Jae Yeol

    2016-01-01

    In late March of 2009, an outbreak of influenza in Mexico, was eventually identified as H1N1 influenza A. In June 2009, the World Health Organization raised a pandemic alert to the highest level. More than 214 countries have reported confirmed cases of pandemic H1N1 influenza A. In Korea, the first case of pandemic influenza A/H1N1 infection was reported on May 2, 2009. Between May 2009 and August 2010, 750,000 cases of pandemic influenza A/H1N1 were confirmed by laboratory test. The H1N1-rel...

  2. (E-1-Phenylethanone semicarbazone

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2009-08-01

    Full Text Available In the title compound, C9H11N3O, the benzene ring is disordered over two positions with refined occupancies of 0.922 (5 and 0.078 (5. The program PLATON [Spek (2009. Acta Cryst. D65, 148–155] recommends the solution in the space group C2/m with a = 7.3050 (3, b = 6.6745 (2, c = 18.3853 (6 Å and β = 96.986 (2°. However, the large number of non-extinct reflections needed to be ignored if C2/m is chosen suggested that the space group is incorrect, even though the R values are lower than that for P21/c. The semicarbazone group is essentially planar, with a maximum deviation of 0.046 (1 Å for one of the N atoms. The mean plane of the semicarbazone group forms dihedral angles of 33.61 (8 and 39.1 (9° with the benzene ring of the major and minor components, respectively. In the crystal structure, molecules are linked by intermolecular N—H...O hydrogen bonds into extended chains along the c axis. The crystal structure is further stabilized by weak intermolucular C—H...π interactions.

  3. The INFN Tier-1

    International Nuclear Information System (INIS)

    INFN-CNAF is the central computing facility of INFN: it is the Italian Tier-1 for the experiments at LHC, but also one of the main Italian computing facilities for several other experiments such as BABAR, CDF, SuperB, Virgo, Argo, AMS, Pamela, MAGIC, Auger etc. Currently there is an installed CPU capacity of 100,000 HS06, a net disk capacity of 9 PB and an equivalent amount of tape storage (these figures are going to be increased in the first half of 2012 respectively to 125,000 HS06, 12 PB and 18 PB). More than 80,000 computing jobs are executed daily on the farm, managed by LSF, accessing the storage, managed by GPFS, with an aggregate bandwidth up to several GB/s. The access to the storage system from the farm is direct through the file protocol. The interconnection of the computing resources and the data storage is based on 10 Gbps technology. The disk-servers and the storage systems are connected through a Storage Area Network allowing a complete flexibility and easiness of management; dedicated disk-servers are connected, also via the SAN, to the tape library. The INFN Tier-1 is connected to the other centers via 3×10 Gbps links (to be upgraded at the end of 2012), including the LHCOPN and to the LHCONE. In this paper we show the main results of our center after 2 full years of run of LHC.

  4. UA1 prototype detector

    CERN Multimedia

    1980-01-01

    Prototype of UA1 central detector inside a plexi tube. The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  5. ATLAS Point 1 Construction

    CERN Multimedia

    Inigo-Golfin, J

    After 3 years of work in point 1, a number of surface buildings have already been completed and handed over to CERN (the control, the gas and the cooling and ventilation buildings) and, probably more appealing to the public, 60,000 m3 of earth have already been excavated from underground. At present, the technical cavern USA15 and its access shaft are almost finished, leaving only the main cavern and the liaison galleries to be completed in the coming year and a half. The main cavern has been excavated down to the radiation limit and its walls and vault will presently be concreted (see below the picture of the section of the vault with the impressive shell of 1.2 m thickness). The excavation of the bench (27 vertical metres to go yet!) will proceed from August, when some additional civil engineering work in the LHC tunnel will be undertaken. Needless to say many different services are necessary around the detector, both for its installation and future operation for physics. To that end much of the heavy...

  6. Tow Tank #1

    Science.gov (United States)

    1930-01-01

    Digging the channel for the Tow Tank. In the late 1920s, the NACA decided to investigate the aero/hydro dynamics of floats for seaplanes. A Hydrodynamics Branch was established in 1929 and special towing basin was authorized in March of that same year. Starr Truscott (the first head of the new division) described the tank in NACA TR 470: 'The N.A.C.A. tank is of the Froude type; that is, the model which is being tested is towed through still water at successive constant speeds from a carriage spanning the tank. At each constant speed the towing pull is measured, the trim and the rise, or change of draft, are recorded and, if the model is being towed at a fixed trim, the moment required to hold it there is measured and recorded.' 'The reinforced concrete basin containing the water has the following dimensions: (1) Length on water, extreme, 2,020 feet; (2) Normal width of water surface, 24 feet; (3) Normal depth of water, 12 feet; (4) Length of 12 foot depth, 1,980 feet.' The tank was dedicated on May 27, 1931. In 1936 the tank was extended to a total length of 2,960 feet. In 1959 the facility was turned over to the U.S. Navy.Published in NACA TR No. 470, 'The N.A.C.A. Tank: A High-Speed Towing Basin for Testing Models of Seaplane Floats,' by Starr Truscott, 1933.

  7. OSS-1/contamination monitor

    Science.gov (United States)

    Kruger, R.; Triolo, J.; McIntosh, R.

    1983-02-01

    A 20-cm high, 18-cm wide, and 30-cm long (8x7x12 inch) box weighing about 7 kg (15 lbs) and consuming about 7 watts of power was carried on the OSS-1 pallet to monitor the mass build-up or accretion of condensible, volatile materials on surfaces in the shuttle bay during all phases of ascent, on-orbit, and descent. Passively thermally controlled, the box holds two witness samples and four actively temperature controlled quartz crystal microbalances (TQCM) whose temperature can vary from -60 C to +80 C. Graphs show the accretion indicated by the TQCM during the launch and early orbital phase. Conditions during tail to the Sun, nose to the Sun, and bay to the Sun attitudes of the shuttle during STS-3 are reflected in temperatures indicated by the OSS-1 thermistor. These temperatures influence outgassing rates of various materials as well as measurements made by the contamination monitor package. The parameters that bear on TQCM measurements data are shown in graphs and discussed.

  8. Main: ALF1NTPARC [PLACE

    Lifescience Database Archive (English)

    Full Text Available ALF1NTPARC S000238 11-Oct-1999 (last modified) kehi ALF-1 (as-1-like sequence bindi...ng factor) binding site found in tobacco (N.t.) parC gene; Found in auxin-responsive regions; as-1-like sequences in parA, par...B and parC bind with ASF-1, ALF-2, and ALF-1, respectively; See S000190 (ABFOS); as-1; ALF-1; par; auxin; tobacco (Nicotiana tabacum); TTACGCAAGCAATGACA ...

  9. Protein: MPA1 [TP Atlas

    Lifescience Database Archive (English)

    Full Text Available MPA1 TLR signaling molecules Nlrp3 Cias1, Mmig1, Nalp3, Pypaf1 NACHT, LRR and PYD domains-containing protein... 3 Cold autoinflammatory syndrome 1 protein homolog, Cryopyrin, Mast cell maturatio...n-associated-inducible protein 1, PYRIN-containing APAF1-like protein 1 10090 Mus musculus 216799 Q8R4B8 Q8R4B8 20007575 ...

  10. Preparation Methods of the Important Intermediate of 1,1,1,3,3,3-Hexafluoropropane——1,1,1,3,3,3-Hexachloropropane%1,1,1,3,3,3-六氟丙烷的重要中间体——1,1,1,3,3,3-六氯丙烷的调聚制备方法

    Institute of Scientific and Technical Information of China (English)

    金文斌; 刘毓林

    2011-01-01

    The batch telomerization preparation methods and continuous telomerization preparation methods of the important intermediate of 1,1,1,3,3,3-hexafluoropropane—1,1,1,3,3,3-hexachloropropane(HCC-230) is reviewed.The advantages and disadvantages are recommended.%主要阐述了1,1,1,3,3,3-六氟丙烷的重要中间体1,1,1,3,3,3-六氯丙烷的间歇调聚和连续调聚制备方法,并比较了两者的优缺点。

  11. ON THE DIOPHANTINE EQUATION (an - 1)((a + 1)n - 1) =x2%关于Diophantine方程(an-1)((a+1)n-1)=x2

    Institute of Scientific and Technical Information of China (English)

    梁明

    2012-01-01

    In this article, the positive integer solution (n, x) of the exponential diophantine equation (αn - 1)((α + l)n-1) = x2 is discussed. Using elementary number theory methods, we prove that, if a = 2 or 3(mod 4), then the equation has no integer solution.%本文研究了指数Diophantine方程(an-1)((a+1)n-1)=x2的正整数解(n,x),其中a是大于1的正整数.运用初等数论方法证明了:当a≡2或3(mod 4)时,该方程无解.

  12. Main: GLUTEBP1OS [PLACE

    Lifescience Database Archive (English)

    Full Text Available GLUTEBP1OS S000048 17-May-1998 (last modified) kehi Glutelin BP-1; Binding site in ...the promoter region of glutelin Gt3 gene family of nuclear factor (PB-1); PB-1 is observed only in nuclear e...xtract of developing seeds; glutelin; nuclear factor; seed; endosperm; BP-1; PB-1; rice (Oryza sativa) AAGCAACACACAAC ...

  13. Investigations on Collectin Liver 1

    DEFF Research Database (Denmark)

    Axelgaard, Esben; Jensen, Lisbeth; Dyrlund, Thomas Franck;

    2013-01-01

    Collectins are pattern recognition molecules of the innate immune system showing binding to carbohydrate structures on microorganisms in a calcium-dependent manner. Recently, three novel collectins, collectin liver 1 (CL-L1), collectin kidney 1 (CL-K1 and CL-11), and collectin placenta 1 (CL-P1...

  14. 26 CFR 1.9002-1 - Purpose, applicability, and definitions.

    Science.gov (United States)

    2010-04-01

    ... applicable provisions of the Act and §§ 1.9002-1 to 1.9002-8, inclusive, shall apply. (b) Eligibility to... regulations thereunder. (c) Definitions. For purposes of the Act and §§ 1.9002-1 to 1.9002-8, inclusive: (1... of his trade or business, of real property or tangible personal property, and (b) Held in a...

  15. Cytochrome P450 (CYP) and glutathione S-transferases (GST) polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1 and GSTT1) and urinary levels of 1-hydroxypyrene in Turkish coke oven workers

    OpenAIRE

    Ahmet Oguz Ada; Meltem Yilmazer; Sinan Suzen; Canan Demiroglu; Ali Eba Demirbag; Sibel Efe; Yavuz Alemdar; Sema Burgaz; Mumtaz Iscan

    2007-01-01

    Genetic polymorphisms of xenobiotic metabolizing enzymes have been associated with cancer risk. We evaluated the influences of genetic polymorphisms of polycyclic aromatic hydrocarbon (PAH) metabolizing enzymes on urinary 1-hydroxypyrene (1-OHP) excretion in Turkish coke oven workers. Urinary 1-OHP was analyzed by HPLC after enzymatic hydrolysis. Lymphocyte DNA was used for PCR-based genotyping of cytochrome P450 (CYP) polymorphisms (CYP1A1 and CYP1B1) and glutathione S-transferases (GST) pol...

  16. Cytochrome P450 (CYP and glutathione S-transferases (GST polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1 and GSTT1 and urinary levels of 1-hydroxypyrene in Turkish coke oven workers

    Directory of Open Access Journals (Sweden)

    Ahmet Oguz Ada

    2007-01-01

    Full Text Available Genetic polymorphisms of xenobiotic metabolizing enzymes have been associated with cancer risk. We evaluated the influences of genetic polymorphisms of polycyclic aromatic hydrocarbon (PAH metabolizing enzymes on urinary 1-hydroxypyrene (1-OHP excretion in Turkish coke oven workers. Urinary 1-OHP was analyzed by HPLC after enzymatic hydrolysis. Lymphocyte DNA was used for PCR-based genotyping of cytochrome P450 (CYP polymorphisms (CYP1A1 and CYP1B1 and glutathione S-transferases (GST polymorphisms (GSTM1, GSTT1 and GSTP1. The mean urinary 1-OHP levels of coke oven workers were significantly higher than that of controls. No significant difference was detected in the mean urinary 1-OHP levels of smokers and non-smokers either for coke oven workers or controls. Genetic polymorphisms of the CYPs and GSTs studied had no significant influence on 1-OHP excretion in coke oven workers, but in the control group the urinary 1-OHP levels of individuals carrying the GSTT1- genotype were significantly higher than those of individuals carrying GSTT1+ genotype. The duration of occupational exposure and metabolic genotype for GSTT1 were the significant predictors of urinary 1-OHP levels. The control individuals carrying combined GSTM1-/GSTT1- genotypes also had significantly higher levels of urinary 1-OHP than those of individuals carrying GSTM1+/GSTTI+, GSTM1-/GSTT1+, and GSTM1+/GSTT1- genotypes. These results indicate that urinary 1-OHP is a sensitive indicator of recent human exposure to PAHs and that genetic polymorphism of GSTT1 may also to some extent reflect the interindividual variation in susceptibility to PAHs only at low PAH exposure.

  17. Type 1 autoimmune pancreatitis

    Directory of Open Access Journals (Sweden)

    Zen Yoh

    2011-12-01

    Full Text Available Abstract Before the concept of autoimmune pancreatitis (AIP was established, this form of pancreatitis had been recognized as lymphoplasmacytic sclerosing pancreatitis or non-alcoholic duct destructive chronic pancreatitis based on unique histological features. With the discovery in 2001 that serum IgG4 concentrations are specifically elevated in AIP patients, this emerging entity has been more widely accepted. Classical cases of AIP are now called type 1 as another distinct subtype (type 2 AIP has been identified. Type 1 AIP, which accounts for 2% of chronic pancreatitis cases, predominantly affects adult males. Patients usually present with obstructive jaundice due to enlargement of the pancreatic head or thickening of the lower bile duct wall. Pancreatic cancer is the leading differential diagnosis for which serological, imaging, and histological examinations need to be considered. Serologically, an elevated level of IgG4 is the most sensitive and specific finding. Imaging features include irregular narrowing of the pancreatic duct, diffuse or focal enlargement of the pancreas, a peri-pancreatic capsule-like rim, and enhancement at the late phase of contrast-enhanced images. Biopsy or surgical specimens show diffuse lymphoplasmacytic infiltration containing many IgG4+ plasma cells, storiform fibrosis, and obliterative phlebitis. A dramatic response to steroid therapy is another characteristic, and serological or radiological effects are normally identified within the first 2 or 3 weeks. Type 1 AIP is estimated as a pancreatic manifestation of systemic IgG4-related disease based on the fact that synchronous or metachronous lesions can develop in multiple organs (e.g. bile duct, salivary/lacrimal glands, retroperitoneum, artery, lung, and kidney and those lesions are histologically identical irrespective of the organ of origin. Several potential autoantigens have been identified so far. A Th2-dominant immune reaction and the activation of

  18. Tokai-1 decommissioning project

    International Nuclear Information System (INIS)

    Tokai-1 (GCR, Gas Cooled Reactor) nuclear power plant of JAPC (the Japan Atomic Power Company) started commercial operation in 1966 as the first commercial nuclear power plant in Japan. The unit had helped introduction and establishment of the construction and operation technologies regarding nuclear power plant at early stage in Japan by its construction and operating experiences. However, The Japan Atomic Power Company (JAPC), the operator and owner of Tokai-1, decided to cease its operation permanently because of a fulfillment of its mission and economical reason. The unit was finally shut down in March 1998 after about 32 year operation. It took about three years for removal of all spent fuels from the site, and then decommissioning started in 2001. JAPC, always on the forefront of the nation's nuclear power generation, is now grappling Japan's first decommissioning of a commercial nuclear power plant, striving to establish effective, advanced decommissioning. The decommissioning for Tokai-1 was scheduled as 20 years project. At the beginning, the reactor was started to be in a static condition ('safe storage period'). While the reactor had been safely stored, the phased decommissioning works started from non-radioactive or low radioactive equipment toward high radioactive equipment. First five years of the project, JAPC concentrated to drain and clean spent fuel cartridge cooling pond and to remove conventional equipments such as turbine, feed water pump and fuel charge machine as planed and budgeted. From 2006, the project came into a new phase. JAPC has been trying to remove four Steam Raising Units (SRUs). The SRUs are huge component (750ton, φ6.3m, H24.7m) of the Gas Cooling Reactor (GCR) and inside of the SRUs are radioactively contaminated. Major concerns are workers safety and minimizing contamination areas during SRU removal. Therefore, JAPC is developing and introducing Jack-down method and remote control multi-functional dismantling system. This

  19. Bis(1-adamantylammonium hexafluoridogermanate

    Directory of Open Access Journals (Sweden)

    Liying Cheng

    2008-01-01

    Full Text Available The title compound, (C10H18N2[GeF6], was obtained hydrothermally from an aqueous solution of GeO2, H3BO3, NiCl2, adamantylammonium chloride, butanol and hydrofluoric acid. The structure consists of discrete bis(1-adamantylammonium cations lying on crystallographic mirror planes and hexafluoridogermanate anions disordered about sites of 2/m point symmetry. In the latter, the Ge atom lies on the site of 2/m symmetry, one F atom lies on the mirror plane and two further F atoms are included in general positions with 50% site occupancy. The cations and anions lie in layers with N—H...F hydrogen bonds formed between them.

  20. Vieillardiixanthone B1

    OpenAIRE

    Boonnak, Nawong; Chantrapromma, Suchada; Fun, Hoong-Kun; Karalai, Chatchanok

    2010-01-01

    The title compound [systematic name: 1,5-dihydr­oxy-3,6-dimeth­oxy-4-(2-methyl­but-3-en-2-yl)-9H-xanthen-9-one], C20H20O6, is a xanthone, which was isolated from the roots of Cratoxylum formosum ssp. pruniflorum. The three rings in the mol­ecule are approximately coplanar, with an r.m.s. deviation of 0.0372 (2) Å for the plane through the 14 non-H atoms. The O atoms of the two hydr­oxy substituents also lie close to this plane with deviations of 0.0669 (2) and 0.1122 (2) Å, respectively. The ...

  1. PMOD 1. 42

    Energy Technology Data Exchange (ETDEWEB)

    Braun, R.L.; Burnham, A.K. (Lawrence Livermore National Lab., CA (United States))

    1991-06-01

    PMOD-Version 1.4 is a copyrighted computer program for simulating oil generation, cracking, and other chemical reactions occuring during the pyrolysis of petroleum source rocks oaver a specified history of temperature and either depth or hydrostatic pressure. The chemical reaction mechanism is defined by the user and, within limits, can be as simple or complex as desired. The model also simulates compaction of the source rock and expulsion of a liquid water phase and a liquid hydrocarbon phase. The expulsion is done by either a simple, constant-fluid-density model or by a more rigorous model using a modified Redlich-Kwong-Soave eqauation of state. The latter model also calculates overpressuring. An auxiliary program, PLOTPMOD, permits graphical display and hardcopy of the results, as well as preperation of ASCII-file subsets of the results for use with a spreadsheet or other graphics program.

  2. The H1 detector

    International Nuclear Information System (INIS)

    The H1 detector presently operating at the HERA e-p collider is described. A general overview of the detector is given with particular emphasis on the calorimeters, the main element of which is a liquid Argon calorimeter enclosed within a large radius solenoid. Calorimetry in the proton direction, close to the beam-pipe is provided by a copper-silicon pad hadronic calorimeter. In the electron direction a lead-scintillator electromagnetic calorimeter closes the solid angle between the rear part of the liquid Argon calorimeter and the beam-pipe. An iron limited streamer tube tail catcher using the return yoke of the solenoid as absorber completes the calorimetry of the detector. The hardware triggers derived from the calorimeters are also described and some performance details of the calorimeters are given

  3. Petroleum resources assessment 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    This report consists of two articles. (1) Petroleum resources assessment of the Okinawa Trough: The hydrocarbon potential has been evaluated for the Tertiary strata in the northwestern margin of the Okinawa Trough on the basis of the pale-ontological, petrological, geochemical data from two wells (Nikkan 8-9 and JDZ 7-3), and geophysical data. (2) Petroliferous basin analysis in Jinju area (2): Petroleum geological studies such as stratigraphy, sedimentology, petrology and organic geochemistry were carried out in the Gyeongsang Supergroup, Junju area. Based on lithofacies and rock color, the sequence can be divided into seven formations which can be organized into two groups (Sindong Group: Nagdong, Hasandong and Jinju formations in ascending order; Hayang Group: Chilgog, Silla Conglomerate, Haman and Jindong formations). (author). 57 refs.

  4. UA1 central detector

    CERN Multimedia

    The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  5. Overview of EHN1

    CERN Multimedia

    1982-01-01

    The beams enter from the bottom of the photo. Starting from left (Jura side)three experiments lay upstream of the European Hybrid Spectrometer (EHS), NA20, NA25 (with a small HOlographic Bubble Chamber, HOBC) and NA24. The EHS houses NA21, NA22 and NA23 with the Rapid Cycling Bubble Chamber RCBC, NA26, NA27 with the HOlographic LExan Bubble Chamber, HOLEBC. Along the beam line most at the right (H8) lays the NA3 setup, while downstream one sees the assembly of the GAMS detector (blue) of the CERN/USSR experiment NA12. At the centre run the beam H2/E2 for the FRAMM experiments NA1 (now completed), NA7 and NA29, and the beam H6 for NA30 and NA11.

  6. Frameworks in CS1

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Caspersen, Michael Edelgaard

    2002-01-01

    In this paper we argue that introducing object-oriented frameworks as subject already in the CS1 curriculum is important if we are to train the programmers of tomorrow to become just as much software reusers as software producers. We present a simple, graphical, framework that we have successfully...... used to introduce the principles of object-oriented frameworks to students at the introductory programming level. Our framework, while simple, introduces central abstractions such as inversion of control, event-driven programming, and variability points/hot-spots. This has provided a good starting...... point for introducing graphical user interface frameworks such as Java Swing and AWT as the students are not overwhelmed by all the details of such frameworks right away but given a conceptual road-map and practical experience that allow them to cope with the complexity....

  7. Main: O2F1BE2S1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available O2F1BE2S1 S000162 17-May-1998 (last modified) kehi opaque-2 recognition site F1 in ...Bertholletia excelsa (Brazil nut tree) 2S storage protein gene (be2S1); O2 protein binds to F1, F2 and F3 sequences of be2S1... promoter; F1 is hybrid C/G box; O2; opaque-2; be2S1; F1; seed; Brazil nut tree (Bertholletia excelsa); TCCACGTCGA ...

  8. The MAT1-1:MAT1-2 ratio of Sporothrix globosa isolates in Japan.

    Science.gov (United States)

    Kano, Rui; Tsui, Clement K-M; Hamelin, Richard C; Anzawa, Kazushi; Mochizuki, Takashi; Nishimoto, Katsutaro; Hiruma, Masataro; Kamata, Hiroshi; Hasegawa, Atsuhiko

    2015-02-01

    In order to understand the reproductive biology of pathogenic species in the Sporothrix schenckii complex, we characterized the partial mating type (MAT1-1) loci of Sporothrix schenckii, as well as the S. globosa MAT1-1-1 gene, which encoded 262 amino acid sequences. The data confirmed that the MAT1-1 locus of S. globosa was divergent from the MAT1-2 locus of the opposite mating type, suggesting that the fungus is heterothallic. To determine the mating type ratio of 20 isolates from Japanese patients, we analyzed the MAT loci by specific PCR amplification of MAT1-1-1 and MAT1-2-1 genes. The MAT1-1-1 was detected in 5 isolates but not in the other 15 isolates with the presence of MAT1-2-1. The MAT1-1:1-2 ratio of S. globosa isolates in Japan was estimated to be 1:3. Phylogenetic analysis indicated that the sequences of the MAT1-1-1 were identical among S. globosa isolates but different from S. schenckii and Ophiostoma montium.

  9. Ape1/Ref-1 Stimulates GDNF/GFRalpha1-mediated Downstream Signaling and Neuroblastoma Proliferation.

    Science.gov (United States)

    Kang, Mi-Young; Kim, Kweon Young; Yoon, Young; Kang, Yoonsung; Kim, Hong Beum; Youn, Cha Kyung; Kim, Dong-Hui; Kim, Mi-Hwa

    2009-10-01

    We previously reported that glial cell line-derived neurotropic factor (GDNF) receptor alpha1 (GFRalpha1) is a direct target of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1). In the present study, we further analyzed the physiological roles of Ape1/Ref-1-induced GFRalpha1 expression in Neuro2a mouse neuroblastoma cells. Ape1/Ref-1 expression caused the clustering of GFRalpha1 immunoreactivity in lipid rafts in response to GDNF. We also found that Ret, a downstream target of GFRalpha1, was functionally activated by GDNF in Ape1/Ref-1-expressing cells. Moreover, GDNF promoted the proliferation of Ape1/Ref-1-expressing Neuro2a cells. Furthermore, GFRalpha1-specific RNA experiments demonstrated that the downregulation of GFRalpha1 by siRNA in Ape1/Ref-1-expressing cells impaired the ability of GDNF to phosphorylate Akt and PLCgamma-1 and to stimulate cellular proliferation. These results show an association between Ape1/Ref-1 and GDNF/GFRalpha signaling, and suggest a potential molecular mechanism for the involvement of Ape1/Ref-1 in neuronal proliferation.

  10. Verification of rod safety via confidence intervals for a binomial proportion

    International Nuclear Information System (INIS)

    The probabilistic safety assessed to a set of N fuel rods assembled in one core of a nuclear power reactor is commonly modelled by Σ i≤N X i, where X 1, ..., X N are independent Bernoulli random variables (rv) with individual probability p i = P (X i = 1) that the ith rod shows no failure during one cycle. This is the probability of the event that the ith rod will not exceed the failure limit during one cycle. The safety standard presently set by the German Reaktor-Sicherheitskommission (Reactor Safety Commission) requires that the expected number of unfailed rods in the core during one cycle is at least N - 1, i.e., E(Σ i≤N X i) = Σ i≤N p i ≥ N - 1, whereby a confidence level of 0.95 for the verification of this condition is demanded. In this paper, we provide an approach, based on the Clopper-Pearson confidence interval for the proportion p of a binomial B(n, p) distribution, how to verify this condition with a confidence level of at least 0.95. We extend our approach to the case, where the set of N fuel rods is arranged in strata, possibly due to different design in each stratum

  11. 26 CFR 1.1202-1 - Deduction for capital gains.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Deduction for capital gains. 1.1202-1 Section 1... (CONTINUED) INCOME TAXES Wash Sales of Stock Or Securities § 1.1202-1 Deduction for capital gains. (a) In computing gross income, adjusted gross income, taxable income, capital gain net income (net capital gain...

  12. 26 CFR 1.1211-1 - Limitation on capital losses.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Limitation on capital losses. 1.1211-1 Section 1... (CONTINUED) INCOME TAXES Treatment of Capital Losses § 1.1211-1 Limitation on capital losses. (a... equal to the sum of: (i) Losses sustained during the taxable year from sales or exchanges of...

  13. 1 CFR 6.1 - Index to daily issues.

    Science.gov (United States)

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Index to daily issues. 6.1 Section 6.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER INDEXES AND ANCILLARIES § 6.1 Index to daily issues. Each daily issue of the Federal Register shall be appropriately indexed....

  14. 26 CFR 1.954-1 - Foreign base company income.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Foreign base company income. 1.954-1 Section 1... (CONTINUED) INCOME TAXES Controlled Foreign Corporations § 1.954-1 Foreign base company income. (a) In... foreign base company income of a controlled foreign corporation. Foreign base company income is...

  15. 26 CFR 1.823-1 - Net premiums.

    Science.gov (United States)

    2010-04-01

    ... TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium Deposits) § 1... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Net premiums. 1.823-1 Section 1.823-1...

  16. 26 CFR 1.664-1 - Charitable remainder trusts.

    Science.gov (United States)

    2010-04-01

    ..., 2007, are contained in § 1.664-1(c) as in effect prior to June 24, 2008. (See 26 CFR part 1, § 1.664-1... administration of a charitable remainder trust, and rules governing the taxation of the trust and its... applicable local law or authorized by the provisions of the governing instrument, the requirement to pay...

  17. 26 CFR 1.501(a)-1 - Exemption from taxation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Exemption from taxation. 1.501(a)-1 Section 1.501... (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(a)-1 Exemption from taxation. (a) In... law or regulations or for other good cause, an organization that has been determined by...

  18. 26 CFR 1.926(a)-1 - Distributions to shareholders.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Distributions to shareholders. 1.926(a)-1... to shareholders. (a) Treatment of distributions. . For guidance, see § 1.926(a)-1T(a). (b) Order of distribution—(1) In general—(i) Distributions by a FSC received by a shareholder in a taxable year of...

  19. 26 CFR 1.1403-1 - Cross references.

    Science.gov (United States)

    2010-04-01

    ...)-1, inclusive. For other administrative provisions relating to the tax on self-employment income, see...) INCOME TAXES Tax on Self-Employment Income § 1.1403-1 Cross references. For provisions relating to the requirement for filing returns with respect to net earnings from self-employment, see § 1.6017-1....

  20. 26 CFR 1.642(e)-1 - Depreciation and depletion.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Depreciation and depletion. 1.642(e)-1 Section 1... (CONTINUED) INCOME TAXES Estates, Trusts, and Beneficiaries § 1.642(e)-1 Depreciation and depletion. An estate or trust is allowed the deductions for depreciation and depletion, but only to the extent...

  1. 37 CFR 1.331-1.334 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false 1.331-1.334 Section 1.331-1.334 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Arbitration Awards §§...

  2. Group divisible designs of four groups and block size five with configuration (1; 1; 1; 2

    Directory of Open Access Journals (Sweden)

    Ronald Mwesigwa

    2016-09-01

    Full Text Available We present constructions and results about GDDs with four groups and block size five in which each block has Configuration $(1, 1, 1, 2$, that is, each block has exactly one point from three of the four groups and two points from the fourth group. We provide the necessary conditions of the existence of a GDD$(n, 4, 5; \\lambda_1, \\lambda_2$ with Configuration $(1, 1, 1, 2$, and show that the necessary conditions are sufficient for a GDD$(n, 4, 5; \\lambda_1,$ $\\lambda_2$ with Configuration $(1, 1, 1, 2$ if $n \

  3. Experimental Conditions: SE18_S1_M1_D1 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available liver and brain by Orbitrap MS and automated search engine Lipid Search SE18_S1 Mouse liver SE18_S1_M1 34.1...phy. SE18_MS1 Preparation of lipid extract and ESI negative detection by LC-MS analysis SE18_DS1 Identification of phospholipids with Lipid Search default ...

  4. 1918 pandemic H1N1 DNA vaccine protects ferrets against 2007 H1N1 virus infection

    DEFF Research Database (Denmark)

    Bragstad, Karoline; Martel, Cyril Jean-Marie; Aasted, Bent;

    of the H1N1 pandemic virus from 1918 induce protection in ferrets against infection with a H1N1 (A/New Caledonia/20/99(H1N1)) virus which was included in the conventional vaccine for the 2006-2007 season. The viruses are separated by a time interval of 89 years and differ by 21.2% in the HA1 protein...

  5. MAN1B1 deficiency: an unexpected CDG-II.

    Directory of Open Access Journals (Sweden)

    Daisy Rymen

    Full Text Available Congenital disorders of glycosylation (CDG are a group of rare metabolic diseases, due to impaired protein and lipid glycosylation. In the present study, exome sequencing was used to identify MAN1B1 as the culprit gene in an unsolved CDG-II patient. Subsequently, 6 additional cases with MAN1B1-CDG were found. All individuals presented slight facial dysmorphism, psychomotor retardation and truncal obesity. Generally, MAN1B1 is believed to be an ER resident alpha-1,2-mannosidase acting as a key factor in glycoprotein quality control by targeting misfolded proteins for ER-associated degradation (ERAD. However, recent studies indicated a Golgi localization of the endogenous MAN1B1, suggesting a more complex role for MAN1B1 in quality control. We were able to confirm that MAN1B1 is indeed localized to the Golgi complex instead of the ER. Furthermore, we observed an altered Golgi morphology in all patients' cells, with marked dilatation and fragmentation. We hypothesize that part of the phenotype is associated to this Golgi disruption. In conclusion, we linked mutations in MAN1B1 to a Golgi glycosylation disorder. Additionally, our results support the recent findings on MAN1B1 localization. However, more work is needed to pinpoint the exact function of MAN1B1 in glycoprotein quality control, and to understand the pathophysiology of its deficiency.

  6. 1 Ft. x 1 Ft. Supersonic Wind Tunnel, Bldg. 37

    Data.gov (United States)

    Federal Laboratory Consortium — The 1- by 1-Foot Supersonic Wind Tunnel (1x), located in the Engine Research Building, is one of the most active test facilities at the Glenn Research Center. Used...

  7. Intestinal and Hepatic Niemann-Pick C1-Like 1

    Directory of Open Access Journals (Sweden)

    Sung-Woo Park

    2013-08-01

    Full Text Available Polytopic transmembrane protein, Niemann-Pick C1-Like 1 (NPC1L1 is localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It mediates intestinal cholesterol absorption and prevents extensive loss of cholesterol by transporting biliary cholesterol into hepatocytes. NPC1L1 is a molecular target of ezetimibe, an agent for hypercholesterolemia. Recently, NPC1L1 inhibition has been shown to prevent metabolic disorders such as fatty liver disease, obesity, diabetes, and atherosclerosis. In this review, the identification and characterization of NPC1L1, NPC1L1-dependent cholesterol transport, the relationship with pathogenesis of metabolic disease and its newly introduced function for virus entry are discussed.

  8. 26 CFR 1.771-1 - Effective date.

    Science.gov (United States)

    2010-04-01

    ... definition; tax imposed ... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effective Date for Subchapter K, Chapter 1 of the Code § 1.771-1 Effective date. (a) General...

  9. Study on characteristic differences of wheat 1Ax1 and 1Ax2* NILS obtained by transgenic HMW-GS 1Dx5 + 1Dy10 gene

    International Nuclear Information System (INIS)

    Use wheat 1Ax1 and 1Ax2* NILS obtained by transgenic HMW-GS 1Dx5 + 1Dy10 gene, characteristics differences have been studied. The two-year results showed that the statistical differences in seed quality parameters, farinogram parameters, extensigram parameters, botany characters and main agricultural characters between 1Ax1 and 1Ax2* were not significant. We considered that 08K860 and 08K871 are similar in hereditary background, 1Ax1 and 1Ax2* have identical contribute on quality. Breeder should attach to 1Ax1 and 1Ax2* identically on wheat breeding. (authors)

  10. ATLAS Data Challenge 1

    CERN Document Server

    DC1 TaskForce

    2003-01-01

    The ATLAS Collaboration at CERN is preparing for the data taking and analysis at LHC that will start in 2007. Therefore, in 2002 a series of Data Challenges (DC's) was started whose goals are the validation of the Computing Model, of the complete software suite, of the data model, and to ensure the correctness of the technical choices to be made. A major feature of the first Data Challenge (DC1) was the preparation and the deployment of the software required for the production of large event samples for the High Level Trigger and Physics communities, and the production of those large data samples as a worldwide distributed activity. It should be noted that it was not an option to "run everything at CERN" even if we had wanted to; the resources were not available at CERN to carry out the production on a reasonable time-scale. We were therefore faced with the great challenge of organising and then carrying out this large-scale production at a significant number of sites around the world. However, the benefits o...

  11. Quenches after LS1

    International Nuclear Information System (INIS)

    In this paper I will give an overview of the different types of quenches that occur in the LHC, followed by an estimate of the number of quenches that we can expect after LS1. Beam-induced quenches and false triggering of the QPS will be the main cause of those quenches that cause a beam dump. Possibly in total up to 10-20 per year. After consolidation of the 13 kA joints, the approach for the BLM settings can be less conservative than in 2010-2012 in order to maximize beam time. This will cause some quenches but, anyhow, a beam.induced quench is not more risky than a quench provoked by false triggering. It is not easy to predict the number of BLM triggered beam dumps, needed to avoid magnet quenches, because it is not sure how to scale beam losses and UFO's from 3.5 TeV to 6.5 TeV, and it is not sure if the thresholds at 3.5 TeV are correct. Quench events will be much more massive (ex: RB quench at 6 kA → 2 MJ, RB quench at 11 kA → 6-20 MJ), and as a result cryo recuperation much longer. There will also be more ramp induced quenches after a FPA in other circuits due to higher ramp rates and smaller temperature margins (mutual coupling)

  12. Transmission electron microscope study of the topotactic reaction of (0 0 1), (0 1 1) and (1 1 1) Ag films and Te

    Energy Technology Data Exchange (ETDEWEB)

    Safran, G.; Geszti, O.; Radnoczi, G

    2003-09-01

    The formation, structure and morphology of silver telluride was investigated in the reaction of (0 0 1), (0 1 1) and (1 1 1) single crystalline Ag films with vacuum deposited Te. Silver films 30-40 nm in thickness were deposited by thermal evaporation onto water- and chlorine-treated NaCl. Onto this silver 1-40 nm of tellurium were deposited at 100 and 200 deg. C. The Ag-Te reaction occurred during Te deposition. Accordingly, formation of the compound phase was investigated from the nucleation stage through complete tellurization on either side of the polymorphic phase transformation temperature (T{sub c}=150 deg. C). Transmission electron microscope and selected area electron diffraction showed that monoclinic silver telluride (Ag{sub 2}Te) of different morphology and texture was always formed. The orientation of silver and monoclinic phase upon differently oriented monocrystalline Ag films and at deposition temperatures around T{sub c} is discussed.

  13. 26 CFR 1.414(s)-1 - Definition of compensation.

    Science.gov (United States)

    2010-04-01

    ... prior regulation provisions of § 1.414(s)-1T. (See § 1.414(s)-1T as contained in the CFR edition revised... to the extent necessary to satisfy the requirements of 29 CFR 2530.204-2(d) (regarding double... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Definition of compensation. 1.414(s)-1 Section...

  14. H1N1快速治疗计

    Institute of Scientific and Technical Information of China (English)

    罗炯尧; 陈艳莲

    2010-01-01

    近来,因为H1N1的流行,使得好多大型聚会都取消了,人们出行的活动也有所减少,大家都有点谈H1N1色变。如果我们能制造出一种H1N1快速治疗仪,那该多好啊!

  15. Main: ASF1NTPARA [PLACE

    Lifescience Database Archive (English)

    Full Text Available ASF1NTPARA S000240 11-Oct-1999 (last modified) kehi ASF-1 (as-1 binding nuclear fac...tor) binding site found in tobacco (N.t.) parA gene; Found in auxin-responsive regions; as-1-like sequences in parA, parB and par...C bind with ASF-1, ALF-2, and ALF-1, respectively; See S000190 (ABFOS), S000238 (ALF1NTPAR...C), S000239 (ALF2NTPARB); as-1; ASF-1; par; auxin; tobacco (Nicotiana tabacum); TTACGCAAGCAATGACAT ...

  16. YY1 positively regulates human UBIAD1 expression

    Energy Technology Data Exchange (ETDEWEB)

    Funahashi, Nobuaki, E-mail: nfunahashi@ri.ncgm.go.jp [Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe (Japan); Department of Metabolic Disorder, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo (Japan); Hirota, Yoshihisa [Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe (Japan); Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka (Japan); Nakagawa, Kimie; Sawada, Natumi; Watanabe, Masato [Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe (Japan); Suhara, Yoshitomo [Department of Bioscience and Engineering, Shibaura Institute of Technology, Saitama (Japan); Okano, Toshio [Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe (Japan)

    2015-05-01

    Vitamin K is involved in bone formation and blood coagulation. Natural vitamin K compounds are composed of the plant form phylloquinone (vitamin K{sub 1}) and a series of bacterial menaquionones (MK-n; vitamin K{sub 2}). Menadione (vitamin K{sub 3}) is an artificial vitamin K compound. MK-4 contains 4-isoprenyl as a side group in the 2-methyl-1,4-naphthoquinone common structure and has various bioactivities. UbiA prenyltransferase domain containing 1 (UBIAD1 or TERE1) is the menaquinone-4 biosynthetic enzyme. UBIAD1 transcript expression significantly decreases in patients with prostate carcinoma and overexpressing UBIAD1 inhibits proliferation of a tumour cell line. UBIAD1 mRNA expression is ubiquitous in mouse tissues, and higher UBIAD1 mRNA expression levels are detected in the brain, heart, kidneys and pancreas. Several functions of UBIAD1 have been reported; however, regulation of the human UBIAD1 gene has not been elucidated. Here we report cloning and characterisation of the human UBIAD1 promoter. A 5′ rapid amplification of cDNA ends analysis revealed that the main transcriptional start site was 306 nucleotides upstream of the translation initiation codon. Deletion and mutation analyses revealed the functional importance of the YY1 consensus motif. Electrophoretic gel mobility shift and chromatin immunoprecipitation assays demonstrated that YY1 binds the UBIAD1 promoter in vitro and in vivo. In addition, YY1 small interfering RNA decreased endogenous UBIAD1 mRNA expression and UBIAD1 conversion activity. These results suggest that YY1 up-regulates UBIAD1 expression and UBIAD1 conversion activity through the UBIAD1 promoter. - Highlights: • We cloned the human UBIAD1 promoter. • The functional importance of the YY1 motif was identified in the UBIAD1 promoter. • YY1 binds the UBIAD1 promoter in vitro and in vivo. • Knockdown of YY1 significantly decreased UBIAD1 expression. • YY1 up-regulates UBIAD1 conversion activity through the UBIAD1

  17. Synthesis and characterization of arsenate antimonic acid AAAc(1 : 1)

    Institute of Scientific and Technical Information of China (English)

    WANG Xue-wen; CHEN Qi-yuan; YIN Zhou-lan; ZHANG Ping-min; WANG Yu-wen

    2005-01-01

    The AAAc(1 : 1) was synthesized in water by As2O3 and Sb2O3 with molar ratio of 1 : 1: AAAc(1 : 1)was characterized by Raman, IR, TG/DTG, DSC, XPS and XRD. The results show that there are four peaks to vsof As-OH, As-O-Sb, Sb-OH and Sb-O-Sb in Raman spectra of AAAc(1 : 1) at 100 - 1 000 cm-1. The solution of AAAc(1 : 1) was also titrated with KOH solution. The titration results show that AAAc(1 : 1) is a hexabasic acid with dissociation constants of k1 = 3.62 × 10-2 , k2 = 3.05 × 10-3 , k3 = 6. 43 × 10-6 , k4 = 9. 78 × 10-8 ,k5 = 1.32 × 10-11 , k6 =3.87 × 10-12. AAAc(1 : 1) has a good solubility and stability in water, its solid obtained by free volatilizing water from its solution under air at ambient temperature is amorphous. Chemical and thermal analyture of AsO ( OH )2-OH-Sb ( OH )4-O-Sb ( OH )4-OH-AsO ( OH )2 or As ( OH )3-O-Sb(OH)4-O-Sb(OH)4-O-As(OH)3 (isomerism) through experimental determination and geometry optimization.

  18. YY1 positively regulates human UBIAD1 expression

    International Nuclear Information System (INIS)

    Vitamin K is involved in bone formation and blood coagulation. Natural vitamin K compounds are composed of the plant form phylloquinone (vitamin K1) and a series of bacterial menaquionones (MK-n; vitamin K2). Menadione (vitamin K3) is an artificial vitamin K compound. MK-4 contains 4-isoprenyl as a side group in the 2-methyl-1,4-naphthoquinone common structure and has various bioactivities. UbiA prenyltransferase domain containing 1 (UBIAD1 or TERE1) is the menaquinone-4 biosynthetic enzyme. UBIAD1 transcript expression significantly decreases in patients with prostate carcinoma and overexpressing UBIAD1 inhibits proliferation of a tumour cell line. UBIAD1 mRNA expression is ubiquitous in mouse tissues, and higher UBIAD1 mRNA expression levels are detected in the brain, heart, kidneys and pancreas. Several functions of UBIAD1 have been reported; however, regulation of the human UBIAD1 gene has not been elucidated. Here we report cloning and characterisation of the human UBIAD1 promoter. A 5′ rapid amplification of cDNA ends analysis revealed that the main transcriptional start site was 306 nucleotides upstream of the translation initiation codon. Deletion and mutation analyses revealed the functional importance of the YY1 consensus motif. Electrophoretic gel mobility shift and chromatin immunoprecipitation assays demonstrated that YY1 binds the UBIAD1 promoter in vitro and in vivo. In addition, YY1 small interfering RNA decreased endogenous UBIAD1 mRNA expression and UBIAD1 conversion activity. These results suggest that YY1 up-regulates UBIAD1 expression and UBIAD1 conversion activity through the UBIAD1 promoter. - Highlights: • We cloned the human UBIAD1 promoter. • The functional importance of the YY1 motif was identified in the UBIAD1 promoter. • YY1 binds the UBIAD1 promoter in vitro and in vivo. • Knockdown of YY1 significantly decreased UBIAD1 expression. • YY1 up-regulates UBIAD1 conversion activity through the UBIAD1 promoter

  19. Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker.

    Science.gov (United States)

    Choi, Sunga; Shin, Ju Hyun; Lee, Yu Ran; Joo, Hee Kyoung; Song, Ki Hak; Na, Yong Gil; Chang, Seok Jong; Lim, Jae Sung; Jeon, Byeong Hwa

    2016-01-01

    Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previously showed that apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) was expressed at an increased level in the serum of BCa patients when compared to the level in healthy controls. In this study, we investigated whether urinary APE1/Ref-1 was also elevated in patients with BCa. In this case-control study, voided urine was collected from 277 subjects including 169 BCa patients and 108 non-BCa controls. Urinary APE1/Ref-1 level was assessed by enzyme-linked immunosorbent assay (ELISA). APE1/Ref-1 levels were significantly elevated in BCa patients relative to levels in non-BCa controls and were correlated with tumor grade and stage. Urinary APE1/Ref-1 levels were also higher in patients with recurrence history of BCa. The receiver operating characteristics (ROC) curve of APE1/Ref-1 showed an area under the curve of 0.83, indicating the reliability and validity of this biomarker. The optimal combination of sensitivity and specificity was determined to be 82% and 80% at a cut-off value of 0.376 ng/100 μL for detection of APE1/Ref-1 in urine. In conclusion, urinary APE1/Ref-1 levels measured from noninvasively obtained body fluids would be clinically applicable for diagnosis of BCa.

  20. UNCORRELATED TWO-MODE SU(1,1) COHERENT STATES

    Institute of Scientific and Technical Information of China (English)

    侯丽珍; 曾高坚

    2001-01-01

    We have constructed a new kind of two-mode bosonic realization of SU(1,1) Lie algebra, on the basis of which the SU(1,1) generalized coherent states in the two-mode Fock space are derived. These two-mode SU(1,1) coherent states,which are called uncorrelated two-mode SU(1,1) coherent states, include three special cases. For these states, we study the mean photon number distribution and their non-classical properties, which are photon anti-bunching, violations of Cauchy-Schwarz inequality and two-mode squeezing.

  1. Cytogenetic damage in Turkish coke oven workers exposed to polycyclic aromatic hydrocarbons: Association with CYP1A1, CYP1B1, EPHX1, GSTM1, GSTT1, and GSTP1 gene polymorphisms.

    Science.gov (United States)

    Ada, Ahmet Oguz; Demiroglu, Canan; Yilmazer, Meltem; Suzen, Halit Sinan; Demirbag, Ali Eba; Efe, Sibel; Alemdar, Yilmaz; Iscan, Mumtaz; Burgaz, Sema

    2013-09-01

    The aim of this study was to determine the frequencies of chromosomal aberrations (CA) and cytochalasin-blocked micronuclei (CBMN) in peripheral blood lymphocytes from Turkish coke oven workers and the influence of CYP1A1, CYP1B1, EPHX1, GSTM1, GSTT1, and GSTP1 gene polymorphisms on these biomarkers. Cytogenetic analysis showed that occupational exposure significantly increased the CA and CBMN frequencies. Gene polymorphisms, on the other hand, did not affect CA or CBMN in either exposed or control subjects. However, due to the limited sample size, our findings need to be verified in future studies with a larger sample. PMID:24084344

  2. SUT1 suppresses sec14-1 through upregulation of CSR1 in Saccharomyces cerevisiae.

    Science.gov (United States)

    Régnacq, Matthieu; Ferreira, Thierry; Puard, Julien; Bergès, Thierry

    2002-11-01

    SUT1 constitutive expression in aerobiosis suppressed the ts phenotype of the sec14-1 mutation, restored growth of the sec14-null mutant and corrected the translocation defect of the vacuolar carboxypeptidase Y. Therefore SUT1 was shown to be a novel potent sec14-1 suppressor. Further, the hypoxic gene CSR1 (YLR380W), a Sec14 homolog, was upregulated upon SUT1 constitutive expression. In addition, SUT1 effects on both sec14-1 suppression and on free sterol composition were abolished in a csr1-null background, showing that this gene acts downstream of SUT1. PMID:12435498

  3. On the transmutation of Am in a fast lead-cooled system

    Indian Academy of Sciences (India)

    B P Kochurov; V N Konev; A Yu Kwaretzkheli

    2007-02-01

    Characteristics of the equilibrium fuel cycle for the core or a blanket of ADS having the structure of the core of a fast lead-cooled reactor of type BREST (Russian abbreviation for `Bystryy Reaktor so Svintsovym Teplonositelem') in a mode of americium transmutation are calculated. Americium loading was taken 5% of heavy atoms. Keeping the average multiplication factor the same as in a standard equilibrium cycle, reactivity swing over 1 year's microcycle is about 1%, that demands partial fuel reloading with a periodicity of about one month. For one year of operation, 61 kg of americium is destroyed, and due to increased 238Pu content, americium is mainly converted to fission products. Thus in a system of 1 GWt (thermal), 87 kg of americium can be transmuted yearly. The estimate of the reactivity void effect has shown that it increases to 0.6% almost linearly with the void fraction increasing up to 25% and reaches its maximum of 0.7% at a void fraction of about 50%. Application of similar strategy for ADS with a sub-criticality level ≈ 0.96–0.98 can essentially relax safety problems related to positive void effects.

  4. Main: AS1CAMV [PLACE

    Lifescience Database Archive (English)

    Full Text Available AS1CAMV S000023 16-Jan-1998 (last modified) kehi as-1 (activation sequence 1) in CaMV...and tobacco; Expression in root and leaf; CaMV 35S promoter; ASF-1; leaf; root; as-1; Cauliflower mosaic virus; CaMV; CCACTGACGTAAGGGATGACGCACAATCC ...

  5. Main: TL1ATSAR [PLACE

    Lifescience Database Archive (English)

    Full Text Available TL1ATSAR S000473 13-August-2005 (last modified) kehi TL1, a consensus sequence over...or of pathogenesis-related genes 1, also known as NIM1; SAR; ER; PR; NIM1; Arabidopsis thaliana CTGAAGAAGAA ...

  6. Main: AGL1ATCONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available AGL1ATCONSENSUS S000338 16-May-2001 (last modified) uchi Binding consensus sequence... of Arabidopsis (A.t.) AGL1 (AGAMOUS-like 1); AGL1 contains MADS domain; See S000339; AGL20 is a MADS domain...ing several MADS-genes underlie development of vegetative structures; MADS; AGL1; AGAMOUS; AGL20; floral ind

  7. What causes type 1 diabetes?

    DEFF Research Database (Denmark)

    Buschard, Karsten

    2011-01-01

    To study type 1 diabetes (T1D), excellent animal models exist, both spontaneously diabetic and virus-induced. Based on knowledge from these, this review focuses on the environmental factors leading to T1D, concentrated into four areas which are: (1) The thymus-dependent immune system: T1D is a T ...

  8. Main: GT1CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available m of GT-1 may be achieved through direct interaction between TFIIA and GT-1; Binding of GT-1-like factors to the PR-1a promoter influ...ences the level of SA-inducible gene expression; GT-1; light; TATA; TFIIA; TBP; HR;

  9. Nucleosome Assembly Protein 1-Like 1 (Nap1l1 Regulates the Proliferation of Murine Induced Pluripotent Stem Cells

    Directory of Open Access Journals (Sweden)

    Yuan Yan

    2016-01-01

    Full Text Available Background/Aims: To investigate whether nucleosome assembly protein 1-like 1 (Nap1l1 regulates the proliferation of induced pluripotent stem cells (iPSC and the potential mechanisms. Methods: Nap1l1-knockdown-iPSC and Nap1l1-overexpression-iPSC were constructed by transfection of lentiviral particles. The proliferation of iPSC was detected by MTT analysis, and cell cycle was analyzed by flow cytometry. Results: Nap1l1 overexpression promoted iPSC proliferation and induced G2/M transition compared to their control iPSC while Nap1l1-knockdown-iPSC dramatically displayed the reduced proliferation and accumulated G2/M phase cells. Further analysis showed that Nap1l1 overexpression in iPSC increased the expression of cyclin B1, downregulated the expression of p21 and p27, while knockdown of Nap1l1 showed the opposite effects. In addition, overexpression of Nap1l1 promoted the phosphorylation of AKT and ERK in iPSC, while knockdown of Nap1l1 inhibited the effects. However, these effects displayed in Nap1l1-overexpression-iPSC were greatly suppressed by the inhibition of AKT or ERK signaling. Conclusions: The results indicate that Nap1l1 promotes the proliferation of iPSC attributable to G2/M transition caused by downregulation of p27 and p21, and upregulation of cyclin B1, the activation of AKT or ERK is involved in the process. The present study has revealed a novel molecular mechanism involved in the proliferation of iPSC.

  10. Spin polarized surface resonance bands in single layer Bi on Ge(1 1 1)

    Science.gov (United States)

    Bottegoni, F.; Calloni, A.; Bussetti, G.; Camera, A.; Zucchetti, C.; Finazzi, M.; Duò, L.; Ciccacci, F.

    2016-05-01

    The spin features of surface resonance bands in single layer Bi on Ge(1 1 1) are studied by means of spin- and angle-resolved photoemission spectroscopy and inverse photoemission spectroscopy. We characterize the occupied and empty surface states of Ge(1 1 1) and show that the deposition of one monolayer of Bi on Ge(1 1 1) leads to the appearance of spin-polarized surface resonance bands. In particular, the C 3v symmetry, which Bi adatoms adopt on Ge(1 1 1), allows for the presence of Rashba-like occupied and unoccupied electronic states around the \\overline{\\text{M}} point of the Bi surface Brillouin zone with a giant spin-orbit constant |{α\\text{R}}| =≤ft(1.4+/- 0.1\\right) eV · Å.

  11. USML-1 Glovebox experiments

    Science.gov (United States)

    Naumann, Robert J.

    1995-01-01

    This report covers the development of and results from three experiments that were flown in the Materials Science Glovebox on USML-1: Marangoni convection in Closed Containers (MCCC), Double Float Zone (DFZ), and Fiber Pulling in Microgravity (FPM). The Glovebox provided a convenient, low cost method for doing simple 'try and see' experiments that could test new concepts or elucidate microgravity phenomena. Since the Glovebox provided essentially one (or possibly two levels of confinement, many of the stringent verification and test requirements on the experiment apparatus could be relaxed and a streamlined test and verification plan for flight qualification could be implemented. Furthermore, the experiments were contained in their own carrying cases whose external configurations could be identified early in the integration sequence for stowage considerations while delivery of the actual experiment apparatus could be postponed until only a few months before flight. This minimized the time fluids must be contained and reduced the possibility of corrosive reactions that could ruin the experiment. In many respects, this exercise was as much about developing a simpler, cheaper way of doing crew-assisted science as it was about the actual scientific accomplishments of the individual experiments. The Marangoni Convection in Closed Containers experiment was designed to study the effects of a void space in a simulated Bridgman crystal growth configuration and to determine if surface tension driven convective flows that may result from thermal gradients along any free surfaces could affect the solidification process. The Fiber Pulling in Microgravity experiment sought to separate the role of gravity drainage from capillarity effects in the break-up of slender cylindrical liquid columns. The Stability of a Double Float Zone experiment explored the feasibility of a quasi-containerless process in which a solidifying material is suspended by two liquid bridges of its own melt.

  12. BOOK REVIEW: Physics 1

    Science.gov (United States)

    Sang, David; Gibbs, Keith; Hutchings, Robert

    2000-09-01

    Physics 1 is an attractive book designed to cover the whole of the AS physics course and has been endorsed by OCR for its Advanced AS and A2 specifications. Built on books from the Cambridge Modular Sciences series, it provides a clearly presented path through each of the three sections: Foundation Physics, Electrons and Photons, and Wave Properties. Each chapter has clearly stated objectives and is peppered with self-assessment questions, the answers to all of which are at the back of the book. Additional questions are given at the end of each chapter. There is an excellent use of colour, summary boxes and diagrams, but relatively few photographs. At the back of the book is a useful section on uncertainties and a glossary. The key feature of this book is its accessibility to students coming from a double-award science background. A great deal of thought has gone into lessening the trauma of the transition to Advanced Level and the results are impressive. Some of the main areas of concern for many students are the mathematical sections. These areas are not rushed, especially in the foundation physics, where there are plenty of worked examples. It is assumed, also, that students will not necessarily be confident with graphs so lots of examples are given. Diagrams of the type of practical equipment students are likely to encounter add another dimension to the book. It is good to see the use of light gates and motion sensors in addition to the more traditional ticker-timers for the calculations of speed and acceleration. Accessibility is the strength of this book. The use of colour and space, as well as the content, make it enjoyable to use and to read for any student embarking on the new AS courses. Helen Reynolds

  13. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility

    International Nuclear Information System (INIS)

    SAMHD1 is a human restriction factor that prevents efficient infection of macrophages, dendritic cells and resting CD4+ T cells by HIV-1. Here we explored the antiviral activity and biochemical properties of human SAMHD1 polymorphisms. Our studies focused on human SAMHD1 polymorphisms that were previously identified as evolving under positive selection for rapid amino acid replacement during primate speciation. The different human SAMHD1 polymorphisms were tested for their ability to block HIV-1, HIV-2 and equine infectious anemia virus (EIAV). All studied SAMHD1 variants block HIV-1, HIV-2 and EIAV infection when compared to wild type. We found that these variants did not lose their ability to oligomerize or to bind RNA. Furthermore, all tested variants were susceptible to degradation by Vpx, and localized to the nuclear compartment. We tested the ability of human SAMHD1 polymorphisms to decrease the dNTP cellular levels. In agreement, none of the different SAMHD1 variants lost their ability to reduce cellular levels of dNTPs. Finally, we found that none of the tested human SAMHD1 polymorphisms affected the ability of the protein to block LINE-1 retrotransposition. - Highlights: • Human SAMHD1 single-nucleotide polymorphisms block HIV-1 and HIV-2 infection. • SAMHD1 polymorphisms do not affect its ability to block LINE-1 retrotransposition. • SAMHD1 polymorphisms decrease the cellular levels of dNTPs

  14. Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea

    Science.gov (United States)

    Liu, Hong; Yang, Fan; Li, Zhiping; Chen, Changzhong; Fang, Zhian; Wang, Lihua; Hu, Yonghua; Chen, Dafang

    2007-01-01

    Objective This study investigated whether the association between passive smoking exposure and dysmenorrhea is modified by two susceptibility genes, CYP1A1MspI and CYP1A1HincII. Methods This report includes 1645 (1124 no dysmenorrhea, 521 dysmenorrhea) nonsmoking and nondrinking newly wed female workers at Anqing, China between June 1997 and June 2000. Multiple logistic regression models were used to estimate the associations of passive smoking exposure and genetic susceptibility with dysmenorrhea, adjusting for perceived stress. Results When stratified by women genotype, the adjusted OR of dysmenorrhea was 1.6 (95%CI=1.3-2.1) for passive smoking group with Ile/Ile462 genotype, and 1.5 (95%CI=1.1-2.1) with C/C6235 genotype, compared to non passive smoking group, respectively. The data further showed that there was a significant combined effect between passive smoking and the CYP1A1 Msp1 C/C6235 and HincII Ile/Ile462 genotype (OR=2.6, 95%CI=1.3-5.2). Conclusion CYP1A1 MspI and HincII genotypes modified the association between passive smoking and dysmenorrhea. PMID:17566695

  15. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility

    Energy Technology Data Exchange (ETDEWEB)

    White, Tommy E.; Brandariz-Nuñez, Alberto; Valle-Casuso, Jose Carlos [Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, 1301 Morris Park – Price Center 501, New York, NY 10461 (United States); Knowlton, Caitlin; Kim, Baek [Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 (United States); Sawyer, Sara L. [Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712 (United States); Diaz-Griffero, Felipe, E-mail: Felipe.Diaz-Griffero@einstein.yu.edu [Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, 1301 Morris Park – Price Center 501, New York, NY 10461 (United States)

    2014-07-15

    SAMHD1 is a human restriction factor that prevents efficient infection of macrophages, dendritic cells and resting CD4+ T cells by HIV-1. Here we explored the antiviral activity and biochemical properties of human SAMHD1 polymorphisms. Our studies focused on human SAMHD1 polymorphisms that were previously identified as evolving under positive selection for rapid amino acid replacement during primate speciation. The different human SAMHD1 polymorphisms were tested for their ability to block HIV-1, HIV-2 and equine infectious anemia virus (EIAV). All studied SAMHD1 variants block HIV-1, HIV-2 and EIAV infection when compared to wild type. We found that these variants did not lose their ability to oligomerize or to bind RNA. Furthermore, all tested variants were susceptible to degradation by Vpx, and localized to the nuclear compartment. We tested the ability of human SAMHD1 polymorphisms to decrease the dNTP cellular levels. In agreement, none of the different SAMHD1 variants lost their ability to reduce cellular levels of dNTPs. Finally, we found that none of the tested human SAMHD1 polymorphisms affected the ability of the protein to block LINE-1 retrotransposition. - Highlights: • Human SAMHD1 single-nucleotide polymorphisms block HIV-1 and HIV-2 infection. • SAMHD1 polymorphisms do not affect its ability to block LINE-1 retrotransposition. • SAMHD1 polymorphisms decrease the cellular levels of dNTPs.

  16. Proinsulin Shares a Motif with Interleukin-1α (IL-1α) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1*

    Science.gov (United States)

    Lee, Siyoung; Kim, Eunsom; Jhun, Hyunjhung; Hong, Jaewoo; Kwak, Areum; Jo, Seunghyun; Bae, Suyoung; Lee, Jongho; Kim, Busun; Lee, Jungmin; Youn, Sulah; Kim, Somi; Kim, Miyeon; Kim, Hyunwoo; Lee, Youngmin; Choi, Dong-Ki; Kim, Yong-Sung; Kim, Soohyun

    2016-01-01

    Although it has been established that diabetes increases susceptibility to infections, the role of insulin (INS) in the immune response is unknown. Here, we investigated the immunological function of INS. Proinsulin dimer (pINSd) was a potent immune stimulus that induced inflammatory cytokines, but mature INS was unable to induce an immune response. An affinity-purified rabbit polyclonal antibody raised against mature IL-1α recognized IL-1α and pINS but failed to detect mature INS and IL-1β. Analysis of the pINS sequence revealed the existence of an INS/IL-1α motif in the C-peptide of pINS. Surprisingly, the INS/IL-1α motif was recognized by monoclonal antibody raised against IL-1α. Deleting the INS/IL-1α motif in pINSd and IL-1α changed their activities. To investigate the pINSd receptor, the reconstitution of IL-1 receptor 1 (IL-1R1) in Wish cells restored pINSd activity that was reversed by an IL-1R antagonist. These data suggested that pINSd needs IL-1R1 for inflammatory cytokine induction. Mouse embryo fibroblast cells of IL-1R1-deficient mice further confirmed that pINSd promotes immune responses through IL-1R1. PMID:27226621

  17. Proinsulin Shares a Motif with Interleukin-1α (IL-1α) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1.

    Science.gov (United States)

    Lee, Siyoung; Kim, Eunsom; Jhun, Hyunjhung; Hong, Jaewoo; Kwak, Areum; Jo, Seunghyun; Bae, Suyoung; Lee, Jongho; Kim, Busun; Lee, Jungmin; Youn, Sulah; Kim, Somi; Kim, Miyeon; Kim, Hyunwoo; Lee, Youngmin; Choi, Dong-Ki; Kim, Yong-Sung; Kim, Soohyun

    2016-07-01

    Although it has been established that diabetes increases susceptibility to infections, the role of insulin (INS) in the immune response is unknown. Here, we investigated the immunological function of INS. Proinsulin dimer (pINSd) was a potent immune stimulus that induced inflammatory cytokines, but mature INS was unable to induce an immune response. An affinity-purified rabbit polyclonal antibody raised against mature IL-1α recognized IL-1α and pINS but failed to detect mature INS and IL-1β. Analysis of the pINS sequence revealed the existence of an INS/IL-1α motif in the C-peptide of pINS. Surprisingly, the INS/IL-1α motif was recognized by monoclonal antibody raised against IL-1α. Deleting the INS/IL-1α motif in pINSd and IL-1α changed their activities. To investigate the pINSd receptor, the reconstitution of IL-1 receptor 1 (IL-1R1) in Wish cells restored pINSd activity that was reversed by an IL-1R antagonist. These data suggested that pINSd needs IL-1R1 for inflammatory cytokine induction. Mouse embryo fibroblast cells of IL-1R1-deficient mice further confirmed that pINSd promotes immune responses through IL-1R1. PMID:27226621

  18. Existence of seven human IL-1R1 promoters

    Directory of Open Access Journals (Sweden)

    Qiming Li

    2010-02-01

    Full Text Available Qiming Li, Hao Zhang, Qun Chen, Ning QuanDepartment of Oral Biology, Ohio State University, Columbus, OH, USAAbstract: Previous studies have reported the existence of three promoters for the human type I interleukin-1 receptor (hIL-1R1 gene. These promoters were discovered by identifying discrete transcription start sites (TSS from limited human cell lines. In this study, we examined the TSSs of hIL-1R1 mRNA from 24 different tissues and identified several novel TSSs in hIL-1R1 that suggest the existence of seven hIL-1R1 promoters: three of them are the same as those reported previously and four are putative novel promoters. Using a promoter-reporter assay, we show here that these promoters can drive the transcription of the reporter gene. In addition, these promoters exhibit cell type specific expression patterns and they can be regulated by enhancer elements in a cell type specific manner. Only one of the promoters was found to be sensitive to the stimulation by glucocorticoids. Similar to our recent report on murine IL-1R1, two of the hIL-1R1 promoters appear to be the dominant promoters, one of which was published previously and the other is identified in the present study. We also found an internal promoter that drives the expression of IL-1R1 after the conventional translation start codon, suggesting that a truncated hIL-1R1 may be expressed by this promoter. These results provide additional information regarding the transcription of hIL-1R1.Keywords: type1 interleukin receptor, human IL-1R1 promoters, transcription start sites, reporter gene, stress hormones, acute phase proteins

  19. Main: ARR1AT [PLACE

    Lifescience Database Archive (English)

    Full Text Available ARR1AT S000454 27-March-2004 (last modified) kehi ARR1-binding element found in Arabidopsis; AR...oglobin-2 (NSHB) gene (Ross et al., 2004); ARR1; Response regulator; Arabidopsis thaliana NGATT ...

  20. Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1)

    International Nuclear Information System (INIS)

    Polyspecific transporters from the organic anion transporting polypeptide (OATP/Oatp) superfamily mediate the uptake of a wide range of compounds. In zebrafish, Oatp1d1 transports conjugated steroid hormones and cortisol. It is predominantly expressed in the liver, brain and testes. In this study we have characterized the transport of xenobiotics by the zebrafish Oatp1d1 transporter. We developed a novel assay for assessing Oatp1d1 interactors using the fluorescent probe Lucifer yellow and transient transfection in HEK293 cells. Our data showed that numerous environmental contaminants interact with zebrafish Oatp1d1. Oatp1d1 mediated the transport of diclofenac with very high affinity, followed by high affinity towards perfluorooctanesulfonic acid (PFOS), nonylphenol, gemfibrozil and 17α-ethinylestradiol; moderate affinity towards carbaryl, diazinon and caffeine; and low affinity towards metolachlor. Importantly, many environmental chemicals acted as strong inhibitors of Oatp1d1. A strong inhibition of Oatp1d1 transport activity was found by perfluorooctanoic acid (PFOA), chlorpyrifos-methyl, estrone (E1) and 17β-estradiol (E2), followed by moderate to low inhibition by diethyl phthalate, bisphenol A, 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4 tetrahydronapthalene and clofibrate. In this study we identified Oatp1d1 as a first Solute Carrier (SLC) transporter involved in the transport of a wide range of xenobiotics in fish. Considering that Oatps in zebrafish have not been characterized before, our work on zebrafish Oatp1d1 offers important new insights on the understanding of uptake processes of environmental contaminants, and contributes to the better characterization of zebrafish as a model species. - Highlights: • We optimized a novel assay for determination of Oatp1d1 interactors • Oatp1d1 is the first SLC characterized fish xenobiotic transporter • PFOS, nonylphenol, diclofenac, EE2, caffeine are high affinity Oatp1d1substrates • PFOA, chlorpyrifos

  1. Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1)

    Energy Technology Data Exchange (ETDEWEB)

    Popovic, Marta; Zaja, Roko [Laboratory for Molecular Ecotoxicology, Division for Marine and Environmental Research, Rudjer Boskovic Institute, Bijenicka 54, 10 000 Zagreb (Croatia); Fent, Karl [University of Applied Sciences Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH-4132 Muttenz (Switzerland); Swiss Federal Institute of Technology (ETH Zürich), Department of Environmental System Sciences, Institute of Biogeochemistry and Pollution Dynamics, CH-8092 Zürich (Switzerland); Smital, Tvrtko, E-mail: smital@irb.hr [Laboratory for Molecular Ecotoxicology, Division for Marine and Environmental Research, Rudjer Boskovic Institute, Bijenicka 54, 10 000 Zagreb (Croatia)

    2014-10-01

    Polyspecific transporters from the organic anion transporting polypeptide (OATP/Oatp) superfamily mediate the uptake of a wide range of compounds. In zebrafish, Oatp1d1 transports conjugated steroid hormones and cortisol. It is predominantly expressed in the liver, brain and testes. In this study we have characterized the transport of xenobiotics by the zebrafish Oatp1d1 transporter. We developed a novel assay for assessing Oatp1d1 interactors using the fluorescent probe Lucifer yellow and transient transfection in HEK293 cells. Our data showed that numerous environmental contaminants interact with zebrafish Oatp1d1. Oatp1d1 mediated the transport of diclofenac with very high affinity, followed by high affinity towards perfluorooctanesulfonic acid (PFOS), nonylphenol, gemfibrozil and 17α-ethinylestradiol; moderate affinity towards carbaryl, diazinon and caffeine; and low affinity towards metolachlor. Importantly, many environmental chemicals acted as strong inhibitors of Oatp1d1. A strong inhibition of Oatp1d1 transport activity was found by perfluorooctanoic acid (PFOA), chlorpyrifos-methyl, estrone (E1) and 17β-estradiol (E2), followed by moderate to low inhibition by diethyl phthalate, bisphenol A, 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4 tetrahydronapthalene and clofibrate. In this study we identified Oatp1d1 as a first Solute Carrier (SLC) transporter involved in the transport of a wide range of xenobiotics in fish. Considering that Oatps in zebrafish have not been characterized before, our work on zebrafish Oatp1d1 offers important new insights on the understanding of uptake processes of environmental contaminants, and contributes to the better characterization of zebrafish as a model species. - Highlights: • We optimized a novel assay for determination of Oatp1d1 interactors • Oatp1d1 is the first SLC characterized fish xenobiotic transporter • PFOS, nonylphenol, diclofenac, EE2, caffeine are high affinity Oatp1d1substrates • PFOA, chlorpyrifos

  2. Tetraaqua{1-[(1H-1,2,3-benzotriazol-1-ylmethyl]-1H-1,2,4-triazole}sulfatozinc(II dihydrate

    Directory of Open Access Journals (Sweden)

    Yan-Zhi Wang

    2010-11-01

    Full Text Available In the title complex, [Zn(SO4(C9H8N6(H2O4]·2H2O, the ZnII ion is six-coordinated by one N atom from a 1-[(1H-1,2,3-benzotriazol-1-ylmethyl]-1H-1,2,4-triazole ligand and five O atoms from one monodentate sulfate anion and four water molecules in a distorted octahedral geometry. The sulfate tetrahedron is rotationally disordered over two positions in a 0.618 (19:0.382 (19 ratio. In the crystal, adjacent molecules are linked through O—H...O and O—H...N hydrogen bonds involving the cation, the anion, and the coordinated and uncoordinated water molecules into a three-dimensional network.

  3. Tetraaqua{1-[(1H-1,2,3-benzotriazol-1-ylmethyl]-1H-1,2,4-triazole}sulfatocadmium dihydrate

    Directory of Open Access Journals (Sweden)

    Yu-xian Li

    2011-09-01

    Full Text Available In the title complex, [Cd(SO4(C9H8N6(H2O4]·2H2O, the CdII ion is six-coordinated by one N atom from a 1-[(1H-1,2,3-benzotriazol-1-ylmethyl]-1H-1,2,4-triazole ligand and by five O atoms from four water molecules and one monodentate sulfate anion in a distorted octahedral geometry. The sulfate tetrahedron is rotationally disordered over two positions in a 0.651 (12:0.349 (12 ratio. In the crystal, adjacent molecules are linked through O—H...O and O—H...N hydrogen bonds into a three-dimensional network.

  4. Cyclin D1, Id1 and EMT in breast cancer

    Directory of Open Access Journals (Sweden)

    Lehn Sophie

    2011-09-01

    Full Text Available Abstract Background Cyclin D1 is a well-characterised cell cycle regulator with established oncogenic capabilities. Despite these properties, studies report contrasting links to tumour aggressiveness. It has previously been shown that silencing cyclin D1 increases the migratory capacity of MDA-MB-231 breast cancer cells with concomitant increase in 'inhibitor of differentiation 1' (ID1 gene expression. Id1 is known to be associated with more invasive features of cancer and with the epithelial-mesenchymal transition (EMT. Here, we sought to determine if the increase in cell motility following cyclin D1 silencing was mediated by Id1 and enhanced EMT-features. To further substantiate these findings we aimed to delineate the link between CCND1, ID1 and EMT, as well as clinical properties in primary breast cancer. Methods Protein and gene expression of ID1, CCND1 and EMT markers were determined in MDA-MB-231 and ZR75 cells by western blot and qPCR. Cell migration and promoter occupancy were monitored by transwell and ChIP assays, respectively. Gene expression was analysed from publicly available datasets. Results The increase in cell migration following cyclin D1 silencing in MDA-MB-231 cells was abolished by Id1 siRNA treatment and we observed cyclin D1 occupancy of the Id1 promoter region. Moreover, ID1 and SNAI2 gene expression was increased following cyclin D1 knock-down, an effect reversed with Id1 siRNA treatment. Similar migratory and SNAI2 increases were noted for the ER-positive ZR75-1 cell line, but in an Id1-independent manner. In a meta-analysis of 1107 breast cancer samples, CCND1low/ID1high tumours displayed increased expression of EMT markers and were associated with reduced recurrence free survival. Finally, a greater percentage of CCND1low/ID1high tumours were found in the EMT-like 'claudin-low' subtype of breast cancer than in other subtypes. Conclusions These results indicate that increased migration of MDA-MB-231 cells following

  5. Transcriptional Auto-Regulation of RUNX1 P1 Promoter.

    Directory of Open Access Journals (Sweden)

    Milka Martinez

    Full Text Available RUNX1 a member of the family of runt related transcription factors (RUNX, is essential for hematopoiesis. The expression of RUNX1 gene is controlled by two promoters; the distal P1 promoter and the proximal P2 promoter. Several isoforms of RUNX1 mRNA are generated through the use of both promoters and alternative splicing. These isoforms not only differs in their temporal expression pattern but also exhibit differences in tissue specificity. The RUNX1 isoforms derived from P2 are expressed in a variety of tissues, but expression of P1-derived isoform is restricted to cells of hematopoietic lineage. However, the control of hematopoietic-cell specific expression is poorly understood. Here we report regulation of P1-derived RUNX1 mRNA by RUNX1 protein. In silico analysis of P1 promoter revealed presence of two evolutionary conserved RUNX motifs, 0.6kb upstream of the transcription start site, and three RUNX motifs within 170bp of the 5'UTR. Transcriptional contribution of these RUNX motifs was studied in myeloid and T-cells. RUNX1 genomic fragment containing all sites show very low basal activity in both cell types. Mutation or deletion of RUNX motifs in the UTR enhances basal activity of the RUNX1 promoter. Chromatin immunoprecipitation revealed that RUNX1 protein is recruited to these sites. Overexpression of RUNX1 in non-hematopoietic cells results in a dose dependent activation of the RUNX1 P1 promoter. We also demonstrate that RUNX1 protein regulates transcription of endogenous RUNX1 mRNA in T-cell. Finally we show that SCL transcription factor is recruited to regions containing RUNX motifs in the promoter and the UTR and regulates activity of the RUNX1 P1 promoter in vitro. Thus, multiple lines of evidence show that RUNX1 protein regulates its own gene transcription.

  6. Gene expression of LOX-1, VCAM-1, and ICAM-1 in pre-atherosclerotic mice

    DEFF Research Database (Denmark)

    Fisker Hag, Anne Mette; Pedersen, Sune Folke; Kjaer, Andreas

    2008-01-01

    To identify markers of the earliest stage of atherosclerosis, endothelial dysfunction, we evaluated the gene expression of lectin-like oxidized-low-density-lipoprotein receptor-1 (LOX-1), vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) in very young pre......-atherosclerotic mice. Furthermore, the plasma levels of the soluble VCAM-1 and ICAM-1 were compared to the gene expression profiles. Gene expressions of LOX-1 and VCAM-1 were up-regulated in young apoE(-/-) mice, and thus, it seems probable that these genes play a role in pre-atherosclerosis. Contrarily, the gene...... expression profile of ICAM-1 did not show any apparent differences between the groups, questioning the involvement of this molecule in the early development of atherosclerosis. Plasma levels of sVCAM-1 and sICAM-1 were similar in all mice and did not correlate with the vascular gene expression...

  7. 26 CFR 1.213-1 - Medical, dental, etc., expenses.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Medical, dental, etc., expenses. 1.213-1 Section... (CONTINUED) INCOME TAXES Additional Itemized Deductions for Individuals § 1.213-1 Medical, dental, etc... treatments affecting any portion of the body, including obstetrical expenses and expenses of therapy or...

  8. 41 CFR 109-1.5108-1 - Equipment.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Equipment. 109-1.5108-1...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property record will be developed and maintained for each item of equipment....

  9. 26 CFR 1.543-1 - Personal holding company income.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Personal holding company income. 1.543-1 Section... (CONTINUED) INCOME TAXES (CONTINUED) Personal Holding Companies § 1.543-1 Personal holding company income. (a) General rule. The term personal holding company income means the portion of the gross income...

  10. (1+1)-维Boussinesq-Burgers方程的Wronskian解

    Institute of Scientific and Technical Information of China (English)

    牛艳霞; 王曦峰; 张俊良

    2013-01-01

    本文利用Hirota双线性化方法,从(1+1)-维Boussinesq-Burgers保谱问题的lax对中,找到适当的函数φ、ψ,进而构造出了(1+1)-维Boussinesq-Burgers方程的Wronskian形式的精确孤子解。

  11. 26 CFR 1.1388-1 - Definitions and special rules.

    Science.gov (United States)

    2010-04-01

    ... TAX (CONTINUED) INCOME TAXES Definitions; Special Rules § 1.1388-1 Definitions and special rules. (a... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Definitions and special rules. 1.1388-1 Section... purposes of such subdivision (iii), net earnings shall not be reduced by any taxes imposed by subtitle A...

  12. ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1

    NARCIS (Netherlands)

    J.D. van Buul; J. van Rijssel; F.P.J. van Alphen; A.M. van Stalborch; E.P.J. Mul; P.L. Hordijk

    2010-01-01

    In the initial stages of transendothelial migration, leukocytes use the endothelial integrin ligands ICAM-1 and VCAM-1 for strong adhesion. Upon adhesion of the leukocyte to endothelial ICAM-1, ICAM-1 is clustered and recruited to the adhered leukocyte, promoting strong adhesion. In this study, we p

  13. 26 CFR 1.162-1 - Business expenses.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Business expenses. 1.162-1 Section 1.162-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED... from such business. In the case of any sports program to which section 114 (relating to sports...

  14. 26 CFR 1.46-1 - Determination of amount.

    Science.gov (United States)

    2010-04-01

    .... Corporation X files an income tax return on a calendar year basis. Corporation Y files an income tax return on..., section 251. (3) Prior regulations. For taxable years beginning before January 1, 1976, see 26 CFR 1.46-1...) Corporation X, a calendar year taxpayer, constructs a ship on which it begins construction on January 1,...

  15. LINE-1 ORF1 protein enhances Alu SINE retrotransposition.

    Science.gov (United States)

    Wallace, Nicholas; Wagstaff, Bradley J; Deininger, Prescott L; Roy-Engel, Astrid M

    2008-08-01

    Retroelements have contributed over one third of the human genome mass. The currently active LINE-1 (L1) codes for two proteins (ORF1p and ORF2p), both strictly required for retrotransposition. In contrast, the non-coding parasitic SINE (Alu) only appears to need the L1 ORF2p for its own amplification. This requirement was previously determined using a tissue culture assay system in human cells (HeLa). Because HeLa are likely to express functional L1 proteins, it is possible that low levels of endogenous ORF1p are necessary for the observed tagged Alu mobilization. By individually expressing ORF1 and ORF2 proteins from both human (L1RP and LRE3) and rodent (L1A102 and L1spa) L1 sources, we demonstrate that increasing amounts of ORF1 expressing vector enhances tagged Alu mobilization in HeLa cells. In addition, using chicken fibroblast cells as an alternate cell culture source, we confirmed that ORF1p is not strictly required for Alu mobilization in our assay. Supporting our observations in HeLa cells, we find that tagged Alu retrotransposition is improved by supplementation of ORF1p in the cultured chicken cells. We postulate that L1 ORF1p plays either a direct or indirect role in enhancing the interaction between the Alu RNA and the required factors needed for its retrotransposition.

  16. 26 CFR 1.7702B-1 - Consumer protection provisions.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Consumer protection provisions. 1.7702B-1 Section 1.7702B-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME...-Term Care Insurance Model Act (Model Act) and Long-Term Care Insurance Model Regulation...

  17. Gromov-Witten Theory of P^1xP^1xP^1

    OpenAIRE

    Karp, Dagan; Ranganathan, Dhruv

    2012-01-01

    We use elementary geometric techniques to exhibit an explicit equivalence between certain sectors of the Gromov-Witten theories of blowups of P^1xP^1xP^1 and P^3. In particular, we prove that the all genus, virtual dimension zero Gromov-Witten theory of the blowup of P^3 at points coincides with that of the blowup at points of P^1xP^1xP^1, for non-exceptional classes. We observe a toric symmetry of the Gromov-Witten theory of P^1xP^1xP^1 analogous and intimately related to Cremona symmetry of...

  18. Data of evolutionary structure change: 1DLFH-1QLRD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DLFH-1QLRD 1DLF 1QLR H D EVKLEESGGGLVQPGGSMKLSCATSGFTFSDAWMDWVRQ...----------------------------------------------------------------- EVQLQQWGAGLLKPSETLSLTCAVYGGSF... 1QLR D 1QL...indel> 1 1QLR D 1QL

  19. Data of evolutionary structure change: 1B1GA-1AK8A [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available entryIDChain>1B1GA KEGDP-NQLSK > - EEE...> A 1AK8A FDKDGDGTITT H ...A LFEEL---DKNGD >HHHHH--- ...entryIDChain>1AK8A LQDMINEVDADGN ...>HHHHH > ATOM 722 CA LEU A 48 3.325 7.917 -3.325 1.00 0

  20. 甲型H1N1流感

    Institute of Scientific and Technical Information of China (English)

    赵苹

    2010-01-01

    @@ 2009年3月以来,许多国家先后发生甲型H1N1流感.甲型H1N1流感原名猪流感,为避免"猪流感"一词对人们的误导,世界卫生组织将此前被称为猪流感的新型致命病毒更名为"AH1N1型流感"(influenza A (H1N1)),我国按惯例称为"甲型H1N1流感". 世卫组织已将该病警告级别提高到6级,表明它将会成为全球性流行病.

  1. (E-1-(Naphthalen-1-yl-3-(1-phenyl-1H-pyrazol-4-ylprop-2-en-1-one

    Directory of Open Access Journals (Sweden)

    Khalid A. Alamry

    2011-10-01

    Full Text Available In the title molecule, C22H16N2O, the phenyl ring is twisted slightly with respect to the plane of the central pyrazole ring [dihedral angle = 14.8 (2°]; the central ring is connected to the naphthyl ring through a —CH=CH—C(=O— fragment, whose C=C double bond has an E configuration. The pyrazole ring and naphthalene ring system are twisted by 46.3 (1°. Weak intermolecular C—H...O hydrogen bonds link the molecules, forming supramolecular chains running along the a axis. The crystal studied was a non-merohedral twin with a component ratio of 0.544 (2:0.456 (2.

  2. First principle calculations of nitric oxide on metallic Pt (1 1 1) and Pt (1 0 0), and bimetallic Au/Pt (1 1 1) and Au/Pt (1 0 0) surfaces

    International Nuclear Information System (INIS)

    Highlights: • The chemisorption of NO on Pt (1 1 1), Pt (1 0 0), Au/Pt (1 1 1) and Au/Pt (1 0 0) has been investigated. • The adsorptive position of NO on metal surface has been discussed. • The interaction between NO and metal surface is mainly NO 5σ/2π* and metal d-bands. • Different compositions and facets can produce varied catalytic effects. - Abstract: The chemisorption of NO on pure Pt (1 1 1) and Pt (1 0 0), bimetallic Au/Pt (1 1 1) and Au/Pt (1 0 0) surfaces has been investigated using the pseudo-potential plane-wave method within the generalized-gradient approximation density functional theory (GGA + DFT). The results show that different surfaces have various effects on the adsorption of NO. NO tends to be adsorbed on site coordinated with more Pt atoms, and the substitution number of the top-layer Pt by Au atoms affect the d-band center and adsorption energy. The local density of states of various surfaces are calculated. With the increasing atomic number of surface Au, the d-band center moves away from the Fermi level, and the adsorption energies decrease. The further electronic states analysis reveals that the interaction between NO and metal surfaces is mainly via the hybridization of NO 5σ/2π* orbitals and metal d-bands. And when the top-layer concentrations of Au are equal, Au/Pt (1 0 0) exhibits better catalytic toward NO adsorption than Au/Pt (1 1 1). It indicates that different compositions and facets can produce varied catalytic effects

  3. Interleukin-1 antagonism in type 1 diabetes of recent onset

    DEFF Research Database (Denmark)

    Moran, Antoinette; Bundy, Brian; Becker, Dorothy J;

    2013-01-01

    Innate immunity contributes to the pathogenesis of autoimmune diseases, such as type 1 diabetes, but until now no randomised, controlled trials of blockade of the key innate immune mediator interleukin-1 have been done. We aimed to assess whether canakinumab, a human monoclonal anti-interleukin-1...... antibody, or anakinra, a human interleukin-1 receptor antagonist, improved β-cell function in recent-onset type 1 diabetes....

  4. Pengaruh Aerasi dan Sumber Nutrien terhadap Kemampuan Alga Filum Chlorophyta dalam Menyerap Karbon (Carbon Sink untuk Mengurangi Emisi CO2 di Kawasan Perkotaan

    Directory of Open Access Journals (Sweden)

    Lancur Setoaji

    2013-09-01

    Full Text Available Penelitian terkait mitigasi pemanasan global, khususnya dalam penyerapan karbon dioksida (CO2, menjadi fokus utama di kalangan ilmuwan dunia. Secara alamiah, karbon dioksida dapat diserap oleh tumbuhan hijau, laut, karbonasi batuan kapur, dan alga. Pigmen hijau dalam alga atau klorofil dapat menyerap karbon dioksida dalam proses fotosintesis. Alga memiliki pertumbuhan yang sangat cepat sehingga cocok digunakan sebagai carbon sink. Penelitian terkait carbon sink ini bertujuan untuk menentukan kemampuan rata-rata serapan CO2 oleh alga di kawasan perkotaan dan menentukan pengaruh aerasi dan variasi sumber N terhadap pertumbuhan dan perkembangan alga. Penelitian ini dilakukan dalam skala laboratorium menggunakan reaktor dengan proses batch. Sampel alga yang digunakan didapatkan dari hasil pengembangbiakan yang bersumber dari perairan di kawasan perkotaan. Penelitian ini menggunakan dua variabel uji, yaitu aerasi dan sumber nutrien. Jumlah karbon dioksida yang diserap didapatkan dari perbandingan stoikiometri pada reaksi fotosintesis.  Berdasarkan perbandingan stoikiometri tersebut diketahui bahwa 1 gram sel alga yang terbentuk sebanding dengan 1,92 gram CO2 yang diserap. Dari hasil penelitian, alga dengan penambahan pupuk urea dapat menyerap 4,87 mg CO2/hari dalam kondisi tanpa aerasi atau 3,84 mg CO2/hari dengan aerasi. Sedangkan alga dengan penambahan pupuk NPK dapat menyerap 3,61 mg CO2/hari dalam kondisi tanpa aerasi atau 3,01 mg CO2/hari dengan aerasi.

  5. Uncertainty analysis for containment response of U.S. EPR TM reactor to large break loss-of-coolant accidents

    International Nuclear Information System (INIS)

    This paper presents an uncertainty analysis applying the GOTHIC containment analysis code to simulate the first 24-hours following a large-break loss-of-coolant accident (LBLOCA) in AREVA's U.S. EPR TM plant. The uncertainty method is modeled after a study performed by the Gesellschaft fur Anlagen und Reaktorsicherheit (GRS) using data from the Heifidampf-Reaktor (HDR) Test T31.5. The analysis method incorporates an assessment of phenomenological importance, identifying the dominant contributors that influence the principle analysis metric, containment pressure. As with the GRS approach, this study employs non-parametric statistics. This analysis illustrates U.S. EPR containment response sensitivity to realistic variation in a set of important model parameters influencing containment conditions during LBLOCA. In considering a set of model uncertainty parameters, a number of GOTHIC variation calculations were performed (59 calculations) to effect a best estimate plus uncertainty result at 95/95 coverage/confidence level for the key metric, containment pressure. The results of the importance analysis showed condensation phenomena on the surface of the containment structures to be important during the passive cooling period, which occurred prior to the start of HL (hot leg) injection of SI (safety injection). In this study, hot leg injection was assumed to initiate at 1.5 hours. Condensation phenomena faded in importance after 1.5 hours due to the hot leg injection of SI suppressing steaming. Structure conduction, especially, the physical properties of concrete, retained importance throughout the transient. (authors)

  6. KONVERSI KATALITIK MINYAK SAWIT UNTUK MENGHASILKAN BIOFUEL MENGGUNAKAN SILIKA ALUMINA DAN HZSM-5 SINTESIS

    Directory of Open Access Journals (Sweden)

    Nurjannah Nurjannah

    2012-02-01

    Full Text Available Terbatasnya sumber energi fosil menyebabkan perlunya pengembangan energi terbarukan yang berasal dari alam dan dapat diperbaharui. Penggunaan bahan bakar minyak bumi, baik dari penggunaan berupa alat transportasi maupun dari penggunaan oleh industri sangat mencemari lingkungan karena tingkat polusi yang ditimbulkan sangat tinggi sehingga perlu mencari bahan bakar alternatif pengganti bahan bakar gasoline, solar, dan kerosene dari minyak nabati. Penelitian dilakukan dalam dua tahapan yaitu sintesa katalis dan proses katalitik cracking. Silika alumina disintesa menggunakan metode Latourette dan HZSM-5 disintesa menggunakan metode Plank. Hasil sintesa dikarakterisasi dengan Penyerapan Spektroskopi Atomis (AAS menunjukkan bahwa silika alumina dan HZSM-5 mempunyai Si/Al 198 dan 243. Luas permukaan  silika alumina dan HZSM-5 diperoleh dari analisa Brunauer Emmet Teller (BET yaitu 149,91-213,35 m2.g-1 dan ukuran pori rata-rata adalah 13oA. Perengkahan katalitik dilakukan dalam suatu mikroreaktor fixed bed pada temperatur 350-500°C dan laju alir gas N2 100-160 ml.min-1 selama 120 min. Hasil perengkahan dianalisa dengan metode gas kromatografi. Hasil yang diperoleh untuk katalis HZSM-5 fraksi gasoline dengan yield tertinggi 28,87%, kerosene 16,70%, dan diesel 12,20%  pada suhu reaktor 4500C dan laju gas N2 100 ml/menit.

  7. DBR1 siRNA inhibition of HIV-1 replication

    Directory of Open Access Journals (Sweden)

    Naidu Yathi

    2005-10-01

    Full Text Available Abstract Background HIV-1 and all retroviruses are related to retroelements of simpler organisms such as the yeast Ty elements. Recent work has suggested that the yeast retroelement Ty1 replicates via an unexpected RNA lariat intermediate in cDNA synthesis. The putative genomic RNA lariat intermediate is formed by a 2'-5' phosphodiester bond, like that found in pre-mRNA intron lariats and it facilitates the minus-strand template switch during cDNA synthesis. We hypothesized that HIV-1 might also form a genomic RNA lariat and therefore that siRNA-mediated inhibition of expression of the human RNA lariat de-branching enzyme (DBR1 expression would specifically inhibit HIV-1 replication. Results We designed three short interfering RNA (siRNA molecules targeting DBR1, which were capable of reducing DBR1 mRNA expression by 80% and did not significantly affect cell viability. We assessed HIV-1 replication in the presence of DBR1 siRNA and found that DBR1 knockdown led to decreases in viral cDNA and protein production. These effects could be reversed by cotransfection of a DBR1 cDNA indicating that the inhibition of HIV-1 replication was a specific effect of DBR1 underexpression. Conclusion These data suggest that DBR1 function may be needed to debranch a putative HIV-1 genomic RNA lariat prior to completion of reverse transcription.

  8. YY1-MIR372-SQSTM1 regulatory axis in autophagy.

    Science.gov (United States)

    Feng, Lifeng; Ma, Yanning; Sun, Jie; Shen, Qi; Liu, Leiming; Lu, Haiqi; Wang, Faliang; Yue, Yongfang; Li, Jiaqiu; Zhang, Shenjie; Lin, Xiaoying; Chu, Jue; Han, Weidong; Wang, Xian; Jin, Hongchuan

    2014-08-01

    Autophagy is a self-proteolytic process that degrades intracellular material to enable cellular survival under unfavorable conditions. However, how autophagy is activated in human carcinogenesis remains largely unknown. Herein we report an epigenetic regulation of autophagy in human cancer cells. YY1 (YY1 transcription factor) is a well-known epigenetic regulator and is upregulated in many cancers. We found that YY1 knockdown inhibited cell viability and autophagy flux through downregulating SQSTM1 (sequestosome 1). YY1 regulated SQSTM1 expression through the epigenetic modulation of the transcription of MIR372 (microRNA 372) which was found to target SQSTM1 directly. During nutrient starvation, YY1 was stimulated to promote SQSTM1 expression and subsequent autophagy activation by suppressing MIR372 expression. Similar to YY1 depletion, MIR372 overexpression blocked autophagy activation and inhibited in vivo tumor growth. SQSTM1 upregulation and competent autophagy flux thus contributed to the oncogenic function of YY1. YY1-promoted SQSTM1 upregulation might be a useful histological marker for cancer detection and a potential target for drug development.

  9. Nucleation and growth of epitaxial ZrB 2(0 0 0 1) on Si(1 1 1)

    Science.gov (United States)

    Hu, C.-W.; Chizmeshya, A. V. G.; Tolle, J.; Kouvetakis, J.; Tsong, I. S. T.

    2004-07-01

    The growth behavior of epitaxial ZrB 2(0 0 0 1) films on Si(1 1 1) via the thermal decomposition of the unimolecular precursor Zr(BH 4) 4 was studied in situ using low-energy electron diffraction and low-energy electron microscopy, and ex situ using cross-sectional transmission electron microscopy and atomic force microscopy. Under appropriate kinetic conditions, epitaxy was achieved in spite of the very large lattice mismatch between ZrB 2(0 0 0 1) and Si(1 1 1). Our study followed the growth from the initial nucleation stage to the final epitaxial film at various growth temperatures. At 900°C, the growth of ZrB 2(0 0 0 1) proceeded by the nucleation of two-dimensional islands. These islands eventually coalesced to form a smooth film with an RMS roughness of 0.9 nm. The interface between ZrB 2(0 0 0 1) and Si(1 1 1) was modeled theoretically and the most favorable interface consisted of the ZrB 2(0 0 0 1) growing on a Si(1 1 1)-(√3×√3)B surface with the Zr-layer nearest to the interface and the B-layer on the top surface.

  10. PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation

    Directory of Open Access Journals (Sweden)

    Lee Hyun Jung

    2012-12-01

    Full Text Available Abstract Background Parkinson disease (PD is characterized by a slow, progressive degeneration of dopaminergic neurons in the substantianigra. The cause of neuronal loss in PD is not well understood, but several genetic loci, including PTEN-induced putative kinase 1 (PINK1, have been linked to early-onset autosomal recessive forms of familial PD. Neuroinflammation greatly contributes to PD neuronal degeneration and pathogenesis. IL-1 is one of the principal cytokines that regulates various immune and inflammatory responses via the activation of the transcription factors NF-κB and activating protein-1. Despite the close relationship between PD and neuroinflammation, the functional roles of PD-linked genes during inflammatory processes remain poorly understood. Methods To explore the functional roles of PINK1 in response to IL-1β stimulation, HEK293 cells, mouse embryonic fibroblasts derived from PINK1-null (PINK1−/− and control (PINK1+/+ mice, and 293 IL-1RI cells stably expressing type 1 IL-1 receptor were used. Immunoprecipitation and western blot analysis were performed to detect protein–protein interaction and protein ubiquitination. To confirm the effect of PINK1 on NF-κB activation, NF-κB-dependent firefly luciferase reporter assay was conducted. Results PINK1 specifically binds two components of the IL-1-mediated signaling cascade, Toll-interacting protein (Tollip and IL-1 receptor-associated kinase 1 (IRAK1. The association of PINK1 with Tollip, a negative regulator of IL-1β signaling, increases upon IL-1β stimulation, which then facilitates the dissociation of Tollip from IRAK1 as well as the assembly of the IRAK1–TNF receptor-associated factor 6 (TRAF6 complex. PINK1 also enhances Lys63-linked polyubiquitination of IRAK1, an essential modification of recruitment of NF-κB essential modulator and subsequent IκB kinase activation, and increases formation of the intermediate signalosome including IRAK1, TRAF6, and

  11. AAS 227: Day 1

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    The mission was featured on the front pages of 450 newspapers worldwide on every single continent (including Antartica!)New Horizons reached the Moon in9 HOURSafter launch (compared to the ~3 days it took the Apollo missions)The mission controllers were aiming for a 100km window of space all the way from EarthThere was a window of ~400seconds which the probe had to arrive within the probe arrived90 seconds early! Putting tardy astronomers everywhere to shame.Charon was the only satellite of Pluto known at the time of the mission proposalThe canyon found on Charon is not only bigger than the Grand Canyon but bigger than Mariner Valley on Mars which is already4000 km (2500 mi) long and reaches depths of up to 7 km (4 mi)!Charons surface. Tectonic feature runs about 1500 km, around 10 km deep. Eat it, Mars. #aas227 pic.twitter.com/blewwJaXEn Danny Barringer (@HeavyFe_H) January 5, 2016The mountains ringing the Sputnik Planum (aka the heart of Pluto) are over 4km high and are snow capped with methane icePlutos mountain ranges. Means surface nitrogen layer is thin, probably water ice according to @AlanStern. #aas227 pic.twitter.com/0yyHZvpBOE Danny Barringer (@HeavyFe_H) January 5, 2016Plutos atmosphere has a dozendistincthaze layers but how they arecreated is a mystery#aas227 hazes on Pluto wow pic.twitter.com/VPx99ZhPj1 Lisa StorrieLombardi (@lisajsl) January 5, 2016Alan also spoke about the future of New Horizons there is a new mission proposal for a fly by of a Kuiper Belt object 2014MU69 in Jan 2019 which should give us a better understanding of this icy frontier at the edge ofthe Solar System. As a parting gift Alan playedthemost gorgeously detailed fly over video of Plutos surface that had all in the room melting into their flip flops. Its safe to say that the whole room is now Pluto-curious and wondering whether a change of discipline is in order!Press Conference: Black Holes and Exoplanets (by Susanna Kohler)This morning marked the first press conference of the meeting

  12. Police Districts, Law, Published in 2012, 1:63360 (1in=1mile) scale, Taylor County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Police Districts dataset, published at 1:63360 (1in=1mile) scale, was produced all or in part from Hardcopy Maps information as of 2012. It is described as...

  13. Gromov-Witten Theory of P^1\\timesP^1\\timesP^1

    CERN Document Server

    Karp, Dagan

    2012-01-01

    We prove equivalences between the Gromov-Witten theories of four blowups of P1\\timesP1\\timesP1 and P3. In particular, we prove that the all genus, virtual dimension zero Gromov-Witten theory of the blowup of P3 at points precisely coincides with that of the blowup at points of P1 \\times P1 \\times P1, for non-exceptional classes. It follows that the all-genus stationary Gromov-Witten theory of P1 \\times P1 \\times P1 coincides with that of P3 in low degree. We also prove there exists a toric symmetry of the Gromov-Witten theory of P1\\timesP1\\timesP1 analogous to and intimately related to Cremona symmetry of P3. Enumerative applications are given.

  14. Synthesis of Some New Derivatives of 1,3-Dichloro-1,1,3,3-tetraphenyldisilazane

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The reactive properties of 1,3-dichloro-1,1,3,3-tetraphenyldisilazane (DCTPS) with water, methanol, phenylamine and lithium salt of hexamethylcyclotrisilazane (D3NLi) were investigated, and four new derivatives were obtained.

  15. Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.

    Science.gov (United States)

    Popovic, Marta; Zaja, Roko; Fent, Karl; Smital, Tvrtko

    2013-11-22

    The organic anion-transporting polypeptide (OATP/Oatp) superfamily includes a group of polyspecific transporters that mediate transport of large amphipathic, mostly anionic molecules across cell membranes of eukaryotes. OATPs/Oatps are involved in the disposition and elimination of numerous physiological and foreign compounds. However, in non-mammalian species, the functional properties of Oatps remain unknown. We aimed to elucidate the role of Oatp1d1 in zebrafish to gain insights into the functional and structural evolution of the OATP1/Oatp1 superfamily. We show that diversification of the OATP1/Oatp1 family occurs after the emergence of jawed fish and that the OATP1A/Oatp1a and OATP1B/Oatp1b subfamilies appeared at the root of tetrapods. The Oatp1d subfamily emerged in teleosts and is absent in tetrapods. The zebrafish Oatp1d1 is similar to mammalian OATP1A/Oatp1a and OATP1B/Oatp1b members, with the main physiological role in transport and balance of steroid hormones. Oatp1d1 activity is dependent upon pH gradient, which could indicate bicarbonate exchange as a mode of transport. Our analysis of evolutionary conservation and structural properties revealed that (i) His-79 in intracellular loop 3 is conserved within OATP1/Oatp1 family and is crucial for the transport activity; (ii) N-glycosylation impacts membrane targeting and is conserved within the OATP1/Oatp1 family with Asn-122, Asn-133, Asn-499, and Asn-512 residues involved; (iii) the evolutionarily conserved cholesterol recognition interaction amino acid consensus motif is important for membrane localization; and (iv) Oatp1d1 is present in dimeric and possibly oligomeric form in the cell membrane. In conclusion, we describe the first detailed characterization of a new Oatp transporter in zebrafish, offering important insights into the functional evolution of the OATP1/Oatp1 family and the physiological role of Oatp1d1.

  16. Study of hypercharge exchange processes 0-1/2+→1- 1/2+

    International Nuclear Information System (INIS)

    In this work we present a formalism for the reconstruction of the transitivity amplitudes governing the processes of the type 0-1/2+→1-1/2+. The formalism uses the information contained in the decay angular correlations and takes into account the existence of mixed spin configurations in the final state 0-1/2+→(0↓, 1-)1/2+ (Author) 10 refs

  17. 1-Benzyl-2-phenyl-1H-benzimidazole–4,4′-(cyclohexane-1,1-diyldiphenol (1/1

    Directory of Open Access Journals (Sweden)

    Chunhua Ge

    2011-07-01

    Full Text Available The asymmetric unit of the title co-crystal, C20H16N2·C18H20O2, contains one molecule of 4,4′-(cyclohexane-1,1-diyldiphenol (in which the cyclohexane ring adopts a chair conformation and one molecule of 1-benzyl-2-phenyl-1H-benzimidazole, which are paired through an O—H...N hydrogen bond. These pairs are further linked by intermolecular O—H...O hydrogen bonds into chains along [010]. Weak intermolecular C—H...O and C—H...π interactions further consolidate the crystal packing. The dihedral angles between the pendant phenyl rings and the benzimidazole ring are 86.9 (2 and 43.1 (2°.

  18. Regional gene expression of LOX-1, VCAM-1, and ICAM-1 in aorta of HIV-1 transgenic rats.

    Directory of Open Access Journals (Sweden)

    Anne Mette Fisker Hag

    Full Text Available BACKGROUND: Increased prevalence of atherosclerotic cardiovascular disease in HIV-infected patients has been observed. The cause of this accelerated atherosclerosis is a matter of controversy. As clinical studies are complicated by a multiplicity of risk-factors and a low incidence of hard endpoints, studies in animal models could be attractive alternatives. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated gene expression of lectin-like oxidized-low-density-lipoprotein receptor-1 (LOX-1, vascular cell adhesion molecule-1 (VCAM-1, and intercellular adhesion molecule-1 (ICAM-1 in HIV-1 transgenic (HIV-1Tg rats; these genes are all thought to play important roles in early atherogenesis. Furthermore, the plasma level of sICAM-1 was measured. We found that gene expressions of LOX-1 and VCAM-1 were higher in the aortic arch of HIV-1Tg rats compared to controls. Also, the level of sICAM-1 was elevated in the HIV-1Tg rats compared to controls, but the ICAM-1 gene expression profile did not show any differences between the groups. CONCLUSIONS/SIGNIFICANCE: HIV-1Tg rats have gene expression patterns indicating endothelial dysfunction and accelerated atherosclerosis in aorta, suggesting that HIV-infection per se may cause atherosclerosis. This transgenic rat model may be a very promising model for further studies of the pathophysiology behind HIV-associated cardiovascular disease.

  19. Main: GT1CORE [PLACE

    Lifescience Database Archive (English)

    Full Text Available GT1CORE S000125 15-Oct-1999 (last modified) kehi Critical for GT-1 binding to box I...I of rbcS; See S000051 GT1MOTIF1; For a compilation of related GT elements and factors, see Villain et al. (

  20. Mosaic type-1 NF1 microdeletions as a cause of both generalized and segmental neurofibromatosis type-1 (NF1).

    Science.gov (United States)

    Messiaen, Ludwine; Vogt, Julia; Bengesser, Kathrin; Fu, Chuanhua; Mikhail, Fady; Serra, Eduard; Garcia-Linares, Carles; Cooper, David N; Lazaro, Conxi; Kehrer-Sawatzki, Hildegard

    2011-02-01

    Mosaicism is an important feature of type-1 neurofibromatosis (NF1) on account of its impact upon both clinical manifestations and transmission risk. Using FISH and MLPA to screen 3500 NF1 patients, we identified 146 individuals harboring gross NF1 deletions, 14 of whom (9.6%) displayed somatic mosaicism. The high rate of mosaicism in patients with NF1 deletions supports the postulated idea of a direct relationship between the high new mutation rate in this cancer predisposition syndrome and the frequency of mosaicism. Seven of the 14 mosaic NF1 deletions were type-2, whereas four were putatively type-1, and three were atypical. Two of the four probable type-1 deletions were confirmed as such by breakpoint-spanning PCR or SNP analysis. Both deletions were associated with a generalized manifestation of NF1. Independently, we identified a third patient with a mosaic type-1 NF1 deletion who exhibited segmental NF1. Together, these three cases constitute the first proven mosaic type-1 deletions so far reported. In two of these three mosaic type-1 deletions, the breakpoints were located within PRS1 and PRS2, previously identified as hotspots for nonallelic homologous recombination (NAHR) during meiosis. Hence, NAHR within PRS1 and PRS2 is not confined to meiosis but may also occur during postzygotic mitotic cell cycles. PMID:21280148

  1. Genetic polymorphisms in CYP1A1, CYP1B1 and COMT genes in Greenlandic Inuit and Europeans

    DEFF Research Database (Denmark)

    Ghisari, Mandana; Long, Manhai; Bonefeld-Jørgensen, Eva Cecilie

    2013-01-01

    . Objectives. The aim of this study was to determine and compare the genotype and allele frequencies of the cytochrome P450 CYP1A1 Ile462Val (rs1048943), CYP1B1 Leu432Val (rs1056836) and catechol-O-methyltransferase COMT Val158Met (rs4680) in Greenlandic Inuit (n=254) and Europeans (n=262) and explore...

  2. 2016 SPD: Day 1

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    Editors note: This week were in Boulder, Colorado at the 47th meeting of the AAS Solar Physics Division (SPD). Follow along to catch some of the latest news from the field of solar physics!The 2016 SPD meeting was launched this morning from the University of Colorado Boulder campus. Two of the hot topics at this years meeting include celebration of the recent move of the National Solar Observatorys headquarters to Boulder, and discussion of the future Daniel K. Inouye Solar Telescope (DKIST, formerly the Advanced Technology Solar Telescope, ATST). DKIST, planned for a 2019 completion in Hawaii, is the next big telescope on the horizon for solar physics.Todays press conference had an interesting focus: instruments providing new high-energy observations of the Sun. Representatives from four different instruments were here to talk about some of the latest X-ray solar observations.GRIPSThe GRIPS payload flew at 130,000 ft over Antarctica on a giant balloon in January 2016. [NASA/Albert Shih]First up, Albert Shih (NASA Goddard) described the Gamma-Ray Imager/Polarimeter for Solar flares, or GRIPS. GRIPS is a balloon-borne instrument designed to detect X-rays and gamma rays emitted during solar flares. Up to tens of a percent of the energy in solar flares is emitted in the form of accelerated particles, but the physics behind this process is not well understood. GRIPS observes where the highest-energy particles are accelerated, in an effort to learn more about the process.GRIPS was launched on 19 January, 2016 and flew for roughly 12 days gathering ~1 million seconds of data! The logistics of this instruments flight are especially interesting, since it was launched from Antarctica and carried by a balloon at a whopping elevation of 130,000 ft (to get high enough that the atmosphere doesnt absorb all the photons GRIPS is trying to observe). Though the data from the mission has been retrieved, the bulk of the hardware remains where it landed at the end of January. It must

  3. Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport

    Science.gov (United States)

    Jia, Lin; Betters, Jenna L.; Yu, Liqing

    2014-01-01

    Increased blood cholesterol is an independent risk factor for atherosclerotic cardiovascular disease. Cholesterol homeostasis in the body is controlled mainly by endogenous synthesis, intestinal absorption, and hepatic excretion. Niemann-Pick C1-Like 1 (NPC1L1) is a polytopic transmembrane protein localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It functions as a sterol transporter to mediate intestinal cholesterol absorption and counterbalances hepatobiliary cholesterol excretion. NPC1L1 is the molecular target of ezetimibe, a potent cholesterol absorption inhibitor that is widely used in treating hypercholesterolemia. Recent findings suggest that NPC1L1 deficiency or ezetimibe treatment also prevents diet-induced hepatic steatosis and obesity in addition to reducing blood cholesterol. Future studies should focus on molecular mechanisms underlying NPC1L1-dependent cholesterol transport and elucidation of how a cholesterol transporter modulates the pathogenesis of metabolic diseases. PMID:20809793

  4. Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels.

    Directory of Open Access Journals (Sweden)

    Xiao-Fei Gao

    Full Text Available (+-SKF 10047 (N-allyl-normetazocine is a prototypic and specific sigma-1 receptor agonist that has been used extensively to study the function of sigma-1 receptors. (+-SKF 10047 inhibits K(+, Na(+ and Ca2+ channels via sigma-1 receptor activation. We found that (+-SKF 10047 inhibited Na(V1.2 and Na(V1.4 channels independently of sigma-1 receptor activation. (+-SKF 10047 equally inhibited Na(V1.2/1.4 channel currents in HEK293T cells with abundant sigma-1 receptor expression and in COS-7 cells, which barely express sigma-1 receptors. The sigma-1 receptor antagonists BD 1063,BD 1047 and NE-100 did not block the inhibitory effects of (+-SKF-10047. Blocking of the PKA, PKC and G-protein pathways did not affect (+-SKF 10047 inhibition of Na(V1.2 channel currents. The sigma-1 receptor agonists Dextromethorphan (DM and 1,3-di-o-tolyl-guanidine (DTG also inhibited Na(V1.2 currents through a sigma-1 receptor-independent pathway. The (+-SKF 10047 inhibition of Na(V1.2 currents was use- and frequency-dependent. Point mutations demonstrated the importance of Phe(1764 and Tyr(1771 in the IV-segment 6 domain of the Na(V1.2 channel and Phe(1579 in the Na(V1.4 channel for (+-SKF 10047 inhibition. In conclusion, our results suggest that sigma-1 receptor agonists directly inhibit Na(V1.2/1.4 channels and that these interactions should be given special attention for future sigma-1 receptor function studies.

  5. Kinetic mixing effect in the 3 -3 -1 -1 model

    Science.gov (United States)

    Dong, P. V.; Si, D. T.

    2016-06-01

    We show that the mixing effect of the neutral gauge bosons in the 3 -3 -1 -1 model comes from two sources. The first one is due to the 3 -3 -1 -1 gauge symmetry breaking as usual, whereas the second one results from the kinetic mixing between the gauge bosons of U (1 )X and U (1 )N groups, which are used to determine the electric charge and baryon minus lepton numbers, respectively. Such mixings modify the ρ -parameter and the known couplings of Z with fermions. The constraints that arise from flavor-changing neutral currents due to the gauge boson mixings and nonuniversal fermion generations are also given.

  6. Main: TCA1MOTIF [PLACE

    Lifescience Database Archive (English)

    Full Text Available TCA1MOTIF S000159 17-May-1998 (last modified) kehi TCA-1 (tobacco nuclear protein 1...) binding site; Related to salicylic acid-inducible expression of many genes; Found in barley beta-1,3-gluca...nase and over 30 different plant genes which are known to be induced by one or more forms of stress; A similar sequence (TCA... et al., 1997); SA; salicylic acid; stress; TCA-1; barley (Hordeum vulgare); tobacco (Nicotiana tabacum); TCATCTTCTT ...

  7. Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1

    Directory of Open Access Journals (Sweden)

    Edavana VK

    2011-11-01

    Full Text Available Vineetha Koroth Edavana1, Xinfeng Yu1, Ishwori B Dhakal1, Suzanne Williams1, Baitang Ning2, Ian T Cook3, David Caldwell1, Charles N Falany3, Susan Kadlubar11Division of Medical Genetics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR, USA; 3Department of Pharmacology, University of Alabama, Birmingham, AL, USAAbstract: Fulvestrant (Faslodex™ is a pure antiestrogen that is approved to treat hormone receptor-positive metastatic breast cancer in postmenopausal women. Previous studies have demonstrated that fulvestrant metabolism in humans involves cytochromes P450 and UDP-glucuronosyltransferases (UGTs. To date, fulvestrant sulfation has not been characterized. This study examined fulvestrant sulfation with nine recombinant sulfotransferases and found that only SULT1A1 and SULT1E1 displayed catalytic activity toward this substrate, with Km of 4.2 ± 0.99 and 0.2 ± 0.16 µM, respectively. In vitro assays of 104 human liver cytosols revealed marked individual variability that was highly correlated with β-naphthol sulfation (SULT1A1 diagnostic substrate; r = 0.98, P < 0.0001, but not with 17ß-estradiol sulfation (SULT1E1 diagnostic substrate; r = 0.16, P = 0.10. Fulvestrant sulfation was correlated with both SULT1A1*1/2 genotype (P value = 0.023 and copy number (P < 0.0001. These studies suggest that factors influencing SULT1A1/1E1 tissue expression and/or enzymatic activity could influence the efficacy of fulvestrant therapy.Keywords: fulvestrant, sulfotransferase, genotype, copy number

  8. Mosaic type-1 NF1 microdeletions as a cause of both generalized and segmental neurofibromatosis type-1 (NF1)

    OpenAIRE

    Messiaen, Ludwine M; Vogt, Julia; Bengesser, Kathrin; Fu, Chuanhua; Mikhail, Fady; Serra, Eduard; Garcia-Linares, Carles; Cooper, David N.; Lázaro, Conxi; Kehrer-Sawatzki, Hildegard

    2011-01-01

    Abstract Mosaicism is an important feature of type-1 neurofibromatosis (NF1) on account of its impact upon both clinical manifestations and transmission risk. Using FISH and MLPA to screen 3500 NF1 patients, we identified 146 individuals harbouring gross NF1 deletions, 14 of whom (9.6%) displayed somatic mosaicism. The high rate of mosaicism in patients with NF1 deletions supports the postulated idea of a direct relationship between the high new mutation rate in this cancer predisp...

  9. Synthesis of (1H)-3,4-Dihydropyrrolo[2,1-c][1,4]oxazin-1-one Derivatives

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In search of new anti-inflammatory and analgesic agents, (1H)-3,4-dihydro- pyrrolo [2,1-c][1,4]oxazin-1-one (3) and its acyl derivatives were designed and prepared. Compound 3 was prepared by treatment of methyl 1-(2-bromoethyl) pyrrole-2-carboxylate with silver oxide and its derivatives were obtained by Friedel-Craftes reaction. Nine of 6-acyl derivatives of compound 3 were prepared.

  10. Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD

    Directory of Open Access Journals (Sweden)

    Arvin B. Tam

    2014-11-01

    Full Text Available An evolutionarily conserved unfolded protein response (UPR component, IRE1, cleaves XBP1/HAC1 introns in order to generate spliced mRNAs that are translated into potent transcription factors. IRE1 also cleaves endoplasmic-reticulum-associated RNAs leading to their decay, an activity termed regulated IRE1-dependent decay (RIDD; however, the mechanism by which IRE1 differentiates intron cleavage from RIDD is not well understood. Using in vitro experiments, we found that IRE1 has two different modes of action: XBP1/HAC1 is cleaved by IRE1 subunits acting cooperatively within IRE1 oligomers, whereas a single subunit of IRE1 performs RIDD without cooperativity. Furthermore, these distinct activities can be separated by complementation of catalytically inactive IRE1 RNase and mutations at oligomerization interfaces. Using an IRE1 RNase inhibitor, STF-083010, selective inhibition of XBP1 splicing indicates that XBP1 promotes cell survival, whereas RIDD leads to cell death, revealing modulation of IRE1 activities as a drug-development strategy.

  11. SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.

    Science.gov (United States)

    Bonifati, Serena; Daly, Michele B; St Gelais, Corine; Kim, Sun Hee; Hollenbaugh, Joseph A; Shepard, Caitlin; Kennedy, Edward M; Kim, Dong-Hyun; Schinazi, Raymond F; Kim, Baek; Wu, Li

    2016-08-01

    SAMHD1 limits HIV-1 infection in non-dividing myeloid cells by decreasing intracellular dNTP pools. HIV-1 restriction by SAMHD1 in these cells likely prevents activation of antiviral immune responses and modulates viral pathogenesis, thus highlighting a critical role of SAMHD1 in HIV-1 physiopathology. Here, we explored the function of SAMHD1 in regulating cell proliferation, cell cycle progression and apoptosis in monocytic THP-1 cells. Using the CRISPR/Cas9 technology, we generated THP-1 cells with stable SAMHD1 knockout. We found that silencing of SAMHD1 in cycling cells stimulates cell proliferation, redistributes cell cycle population in the G1/G0 phase and reduces apoptosis. These alterations correlated with increased dNTP levels and more efficient HIV-1 infection in dividing SAMHD1 knockout cells relative to control. Our results suggest that SAMHD1, through its dNTPase activity, affects cell proliferation, cell cycle distribution and apoptosis, and emphasize a key role of SAMHD1 in the interplay between cell cycle regulation and HIV-1 infection. PMID:27183329

  12. CYP1A1, GSTM1, GSTT1 and TP53 Polymorphisms and Risk of Gallbladder Cancer in Bolivians.

    Science.gov (United States)

    Sakai, Kazuaki; Loza, Ernesto; Roig, Guido Villa-Gomez; Nozaki, Ryoko; Asai, Takao; Ikoma, Toshikazu; Tsuchiya, Yasuo; Kiyohara, Chikako; Yamamoto, Masaharu; Nakamura, Kazutoshi

    2016-01-01

    The Plurinational State of Bolivia (Bolivia) has a high incidence rate of gallbladder cancer (GBC). However, the genetic and environmental risk factors for GBC development are not well understood. We aimed to assess whether or not cytochrome P450 (CYP1A1), glutathione S-transferase mu 1 (GSTM1), theta 1 (GSTT1) and tumor suppressor protein p53 (TP53) genetic polymorphisms modulate GBC susceptibility in Bolivians. This case-control study covered 32 patients with GBC and 86 healthy subjects. GBC was diagnosed on the basis of histological analysis of tissues at the Instituto de Gastroenterologia Boliviano-Japones (IGBJ); the healthy subjects were members of the staff at the IGBJ. Distributions of the CYP1A1 rs1048943 and TP53 rs1042522 polymorphisms were assayed using PCR-restriction fragment length polymorphism assay. GSTM1 and GSTT1 deletion polymorphisms were detected by a multiplex PCR assay. The frequency of the GSTM1 null genotype was significantly higher in GBC patients than in the healthy subjects (odds ratio [OR], 2.35; 95% confidence interval [CI], 1.03-5.37; age-adjusted OR, 3.53; 95% CI, 1.29-9.66; age- and sex-adjusted OR, 3.40; 95% CI, 1.24-9.34). No significant differences were observed in the frequencies of CYP1A1, GSTT1, or TP53 polymorphisms between the two groups. The GSTM1 null genotype was associated with increased GBC risk in Bolivians. Additional studies with larger control and case populations are warranted to confirm the association between the GSTM1 deletion polymorphism and GBC risk suggested in the present study.

  13. Data of evolutionary structure change: 1BFTA-1NFKB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1BFTA-1NFKB 1BFT 1NFK A B ---------------------------------------...EACIRGYNPGLLVHSDLAYLQAEGGGDRQLTDREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGE... 1BFT A 1BFTA YFTGP-

  14. DSS1/Sem1, a multifunctional and intrinsically disordered protein

    DEFF Research Database (Denmark)

    Kragelund, Birthe Brandt; Schenstrøm, Signe Marie; Rebula, Caio A.;

    2016-01-01

    DSS1/Sem1 is a versatile intrinsically disordered protein. Besides being a bona fide subunit of the 26S proteasome, DSS1 associates with other protein complexes, including BRCA2-RPA, involved in homologous recombination; the Csn12-Thp3 complex, involved in RNA splicing; the integrator, involved...... in transcription; and the TREX-2 complex, involved in nuclear export of mRNA and transcription elongation. As a subunit of the proteasome, DSS1 functions both in complex assembly and possibly as a ubiquitin receptor. Here, we summarise structural and functional aspects of DSS1/Sem1 with particular emphasis on its...... multifunctional and disordered properties. We suggest that DSS1/Sem1 can act as a polyanionic adhesive to prevent nonproductive interactions during construction of protein assemblies, uniquely employing different structures when associating with the diverse multisubunit complexes....

  15. ERF1 -- Enhanced River Reach File 1.2

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — U.S. Environmental Protection Agency's River Reach File 1 (RF1)to ensure the hydrologic integrity of the digital reach traces and to quantify the mean water time of...

  16. 2016 Mission Operations Working Group: Earth Observing-1 (EO-1)

    Science.gov (United States)

    Frye, Stuart

    2016-01-01

    EO-1 Mission Status for the Constellation Mission Operations Working Group to discuss the EO-1 flight systems, mission enhancements, debris avoidance maneuver, orbital information, 5-year outlook, and new ground stations.

  17. General Unitary SU(1,1) TFD Formulation

    OpenAIRE

    Abdalla, M. C. B.; Gadelha, A. L.

    2003-01-01

    In this work we discuss a generalization for the thermal Bogoliubov transformation in the context of a hermitian general SU(1,1) transformation generator. The TFD tilde conjugation rules are redefined using an appropriated Tomita-Takesaki modular operator.

  18. General Unitary SU(1,1) TFD Formulation

    CERN Document Server

    Abdalla, Maria Christina B

    2004-01-01

    In this work we discuss a generalization for the thermal Bogoliubov transformation in the context of a hermitian general SU(1,1) transformation generator. The TFD tilde conjugation rules are redefined using an appropriated Tomita-Takesaki modular operator.

  19. Effect of APE1 T2197G (Asp148Glu Polymorphism on APE1, XRCC1, PARP1 and OGG1 Expression in Patients with Colorectal Cancer

    Directory of Open Access Journals (Sweden)

    Juliana C. Santos

    2014-09-01

    Full Text Available It has been hypothesized that genetic variation in base excision repair (BER might modify colorectal adenoma risk. Thus, we evaluated the influence of APE1 T2197G (Asp148Glu polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in normal and tumor samples from patients with colorectal cancer. The results indicate a downregulation of OGG1 and an upregulation of XRCC1 expression in tumor tissue. Regarding the anatomical location of APE1, OGG1 and PARP-1, a decrease in gene expression was observed among patients with cancer in the rectum. In patients with or without some degree of tumor invasion, a significant downregulation in OGG1 was observed in tumor tissue. Interestingly, when taking into account the tumor stage, patients with more advanced grades (III and IV showed a significant repression for APE1, OGG1 and PARP-1. XRCC1 expression levels were significantly enhanced in tumor samples and were correlated with all clinical and histopathological data. Concerning the polymorphism T2197G, GG genotype carriers exhibited a significantly reduced expression of genes of the BER repair system (APE1, XRCC1 and PARP1. In summary, our data show that patients with colorectal cancer present expression changes in several BER genes, suggesting a role for APE1, XRCC1, PARP1 and OGG1 and APE1 polymorphism in colorectal carcinogenesis.

  20. 26 CFR 1.267(f)-1 - Controlled groups.

    Science.gov (United States)

    2010-04-01

    ... significant purpose the avoidance of Federal income tax. (f) Receivables. If S acquires a receivable from the... section. See, e.g., §§ 1.312-6(a), 1.312-7, and 1.1502-33(c)(2). (h) Anti-avoidance rule. If a transaction... the land for sale to customers in the ordinary course of business. On July 1 of Year 3, B sells...

  1. Germline Mutation of INI1/SMARCB1 in Familial Schwannomatosis

    OpenAIRE

    Hulsebos, Theo J. M.; Plomp, Astrid S.; Wolterman, Ruud A.; Robanus-Maandag, Els C.; Baas, Frank; Wesseling, Pieter

    2007-01-01

    Patients with schwannomatosis develop multiple schwannomas but no vestibular schwannomas diagnostic of neurofibromatosis type 2. We report an inactivating germline mutation in exon 1 of the tumor-suppressor gene INI1 in a father and daughter who both had schwannomatosis. Inactivation of the wild-type INI1 allele, by a second mutation in exon 5 or by clear loss, was found in two of four investigated schwannomas from these patients. All four schwannomas displayed complete loss of nuclear INI1 p...

  2. On Hardy's Theorem on SU(1,1)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The classical Hardy theorem asserts that f and its Fourier transform (f) can not both be very rapidly decreasing. This theorem was generalized on Lie groups and also for the Fourier-Jacobi transform. However, on SU(1, 1) there are infinitely many "good"functions in the sense that f and its spherical Fourier transform (f) both have good decay.In this paper, we shall characterize such functions on SU(1,1).

  3. Interleukin 1 is a radioprotector

    International Nuclear Information System (INIS)

    Pretreatment with recombinant interleukin 1 (IL 1) protects mice in a dose-dependent manner from lethal effects of ionizing radiation. Two thousand units of IL 1, given i.p. 20 hr before irradiation, protect 88% of C57B1/6 mice from an LD100/17 radiation dose (dose of radiation that kills 100% mice in 17 days), and 1000 U of IL 1 protect 100% of DBA/1 mice from an LD50/30 dose. This finding provides the first evidence that a cytokine, IL 1, which acts as a differentiation- and maturation-inducing agent for a variety of cells, also can serve as a signal that initiates radioprotective events in vivo. Because many of the exogenous immunomodulators that have been shown to be radioprotective also induce endogenous IL 1 production, our observation suggests that IL 1 may mediate their radioprotective effects

  4. Index to the Journal of American Indian Education, Vol. 1, No. 1 - Vol. 8, No. 1.

    Science.gov (United States)

    Loomis, Charlotte Ann

    All articles (112) that appeared in the "Journal of American Indian Education" (JAIE), Vol. 1., No. 1 (June 1961) through Vol. 8, No 1 (October 1968) are indexed and annotated. The publication is divided into 3 parts: (1) annotations listed in order of appearance in JAIE by volume, number, and page; (2) author index; and (3) subject index. Later…

  5. Johnston Atoll Site 1A-P 1/23/2006 0-1M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Onemetersquare 1 meter x 1 meter benthic substrate at Johnston Atoll, site 1AP 16 46.909N, 169 27.757W, between 0 and 1 meters along a permanent transect.

  6. Data of evolutionary structure change: 1DSUA-1C1MA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available n>1DSUA SVQLN----GAHLC >EEEE ---- Eucture... A 1C1MA SLQYRSGSSWAHTC ...>EEEEEE EEE E> ATOM 123 CA SER A 32 -2.328 59.41...CAESN-RRDSC e>EE - EEEture...ence>CAGGDGVRSGC >EE EEE> ATOM 1

  7. Johnston Atoll Site 1A-P 1/23/2006 1-2M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Johnston Atoll, site 1A-P (16 46.909N, 169 27.757W), between 1 and 2 meters along a permanent transect.

  8. RANCANG BANGUN ALAT PENJERNIH AIR LIMBAH CAIR LAUNDRY DENGAN MENGGUNAKAN MEDIA PENYARING KOMBINASI PASIR – ARANG AKTIF

    Directory of Open Access Journals (Sweden)

    Hery Setyobudiarso

    2014-05-01

    Full Text Available Perkembangan jasa pencucian pakaian (laundry berkontribusi pada peningkatan penggunaan air tanah dan pemakaian deterjen sehingga menghasilkan limbah cair yang dapat mencemari lingkungan. Oleh karena itu, diperlukan sistem pengolahan air limbah laundry menjadi air bersih. Tujuan penelitian ini adalah menentukan pengaruh bahan penyaring pasir silika, zeolit dan arang aktif terhadap hasil olahan air limbah laundry dan mengetahui  pengaruh tekanan dan waktu pemakaian reaktor penyaring. Metode pengolahan yang digunakan adalah filtrasi menggunakan filtrasi pasir silika, adsorpsi karbon aktif, serta gabungan pengolahan filtrasi pasir aktif dan adsorpsi karbon aktif untuk menghasilkan air bersih. Hasil penelitian menunjukkan bahwa metode pengolahan koagulasi dan flokulasi, filtrasi pasir aktif, adsorpsi karbon aktif serta gabungan filtrasi pasir aktif dan adsorpsi karbon aktif mampu menurunkan kekeruhan hingga batas maksimum air bersih. Karakteristik limbah laundry pada tekanan 1 bar memiliki nilai warna, COD dan TSS yang cenderung menurun dari menit ke 20 hingga menit ke 60 , warna nilai 138, COD 908 mg/l dan TSS 215 mg/l. Sedangkan pada tekanan 2 bar memiliki nilai warna, COD dan TSS yang cenderung menurun dari menit ke 20 hingga menit ke 60 , masing-masing masing-masing warna nilai 40, COD 746 mg/l dan TSS 210 mg/l.  Air yang dihasilkan bukan merupakan air bersih tetapi aman untuk dibuang ke lingkungan.

  9. The evolution of the break preclusion concept for nuclear power plants in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, H. [Gesellschaft fuer Anlagen- und Reaktorsicherheit, Koeln (Germany)

    1997-04-01

    In the updating of the Guidelines for PWR`s of the {open_quotes}Reaktor-Sicherheitskommission{close_quotes} (RSK) in 1981 the requirements on the design have been changed with respect to the postulated leaks and breaks in the primary pressure boundary. The major change was a revision in the requirements for pipe whip protection. As a logical consequence of the {open_quotes}concept of basic safety{close_quotes} a guillotine type break or any other break type resulting in a large opening is not postulated any longer for the calculation of reaction and jet forces. As an upper limit for a leak an area of 0, 1 A (A = open cross section of the pipe) is postulated. This decision was based on a general assessment of the present PWR system design in Germany. Since then a number of piping systems have been requalified in the older nuclear power plants to comply with the break preclusion concept. Also a number of extensions of the concept have been developed to cover also leak-assumptions for branch pipes. Furthermore due considerations have been given to other aspects which could contribute to a leak development in the primary circuit, like vessel penetrations, manhole covers, flanges, etc. Now the break preclusion concept originally applied to the main piping has been developed into an integrated concept for the whole pressure boundary within the containment and will be applied also in the periodic safety review of present nuclear power plants.

  10. Penurunan Kandungan Zat Kapur dalam Air Tanah dengan Menggunakan Media Zeolit Alam dan Karbon Aktif Menjadi Air Bersih

    Directory of Open Access Journals (Sweden)

    Gianina Qurrata Dinora

    2013-09-01

    Full Text Available Salah satu syarat kimia yang harus dipenuhi dalam air bersih adalah kesadahan. Salah satu penyebab utama terjadinya kesadahan adalah kandungan Ca2+ (kesadahan kalsium atau biasanya disebut air kapur. Selain kandungan air kapur yang tinggi, penyebab air tanah tidak dapat langsung digunakan adalah kadungan besi dan mangan yang tinggi pula. Untuk itu, dibutuhkan unit filter skala rumah tangga yang dapat menjadi pengolahan alternatif untuk memenuhi kebutuhan air bersih. Penelitian ini  bertujuan untuk mendapatkan komposisi media filter yang efektif dan effisien untuk penyisihan kesadahan kalsium, Fe, dan Mn dalam air tanah dan mendapatkan waktu breakthrough. Media filter yang digunakan pada penelitian ini adalah media zeolit alam dan karbon aktif disusun secara stratifikasi dengan perbandingan ketinggian pada masing-masing reaktor filter. Media filter tersebut akan dialiri dengan tiga variasi konsentrasi kesdahan kalsium. Hasil dari penelitian ini, didapatkan komposisi media yang paling efektif dalam menurunkan kandungan kesadahan kalsium adalah komposisi III dengan perbandingan ketinggian media zeolit alam dan karbon aktif sebesar 30 cm : 60 cm. Pada variasi konsentrasi 1 mampu melakukan penyisihan sebesar 96,52%, konsentrasi 2 mampu melakukan penyisihan sampai 94,67%, dan konsentrasi 3 mampu melakukan penyisihan sebesar 90,22%

  11. HIDRORENGKAH METIL ESTER ASAM LEMAK (MEPO MENGGUNAKAN ZEOLIT ALAM TERAKTIVASI HYDROCRACKING OF FATTY ACID METIL ESTER (FAME USING ACTIVATED NATURAL ZEOLITE

    Directory of Open Access Journals (Sweden)

    Lina Mahardiani

    2011-11-01

    Full Text Available Dalam upaya untuk menghasilkan rantai pendek hidrokarbon yang berasal dari minyak sawit, telah dilakukan hidrorengkah metil ester asam lemak (MEPO menggunakan katalis nikel yang diembankan pada zeolit alam aktif (NZA. Zeolit alam (NZ perlakuan asam dilanjutkan dengan kalsinasi selama 1 jam pada suhu 500 oC diperoleh katalis NZA. Impregnasi Ni menggunakan prekusor Ni(NO32.6H2O dilakukan dengan memvariasikan kandungan Ni sebesar 2,5 dan 8% dari berat NZA yang menghasilkan katalis Ni/NZA2, Ni/NZA5 dan Ni/NZA8. Hidrorengkah metil ester asam lemak dilakukan pada reaktor fixed-bed. Kondisi reaksi meliputi waktu retensi 30 menit, laju alir gas hidrogen 20 ml/min dan suhu reaksi 400, 450 dan 500 oC. Produk cair hasil reaksi hidrorengkah dianalisis menggunakan kromatografi gas (GC. Dari proses uji aktivitas katalis didapatkan persentase produk optimum pada jenis katalis Ni/NZA8, yaitu fraksi bensin 29,85% dan fraksi solar 18,03% pada temperatur 500 oC.

  12. Data of evolutionary structure change: 1ACLA-1MAAD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACLA-1MAAD 1ACL 1MAA A D --SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPV...FGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRF... 0 1ACL A 1ACLA SPRPK-STTVM 1 1ACL

  13. Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter

    DEFF Research Database (Denmark)

    Larsen, Philip J; Holst, Jens Juul

    2005-01-01

    normal and pathophysiological role of GLP-1 have been published over the last two decades and our understanding of GLP-1 action has widened considerably. In the present review, we have tried to cover our current understanding of GLP-1 actions both as a peripheral hormone and as a central neurotransmitter...

  14. 26 CFR 1.414(q)-1 - Highly compensated employee.

    Science.gov (United States)

    2010-04-01

    ... qualified separate line of business. (i)-(iii) . See § 1.414(q)-1T, Q&A-9(b)(1) (i) through (iii) for... requirement applicable to a qualified separate line of business. (2) Excluded employees—(i) Age and...

  15. 26 CFR 1.848-1 - Definitions and special provisions.

    Science.gov (United States)

    2010-04-01

    ... to January 1, 1985, if the premiums on the contract are reported as life insurance premiums on the insurance company's annual statement (or could be reported as life insurance premiums if the company were... coverage and group term life insurance coverage to X's employees. L1 charges a premium of $1,000 for...

  16. Wilms' tumour gene 1 (WT1) in human neoplasia.

    NARCIS (Netherlands)

    Keilholz, U.; Menssen, H.D.; Gaiger, A.; Menke, A.; Oji, Y.; Oka, Y.; Scheibenbogen, C.; Stauss, H.; Thiel, E. van; Sugiyama, H.

    2005-01-01

    The transcription factor Wilms' tumour gene 1 (WT1) is important as a prognostic marker as well as in the detection and monitoring of minimal residual disease in leukaemia and myelodysplastic syndromes. Evidence has accumulated over the past decade to show that WT1 is a key molecule for tumour proli

  17. 26 CFR 1.88-1 - Nuclear decommissioning costs.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Nuclear decommissioning costs. 1.88-1 Section 1... decommissioning costs. (a) In general. Section 88 provides that the amount of nuclear decommissioning costs... collect nuclear decommissioning costs from ratepayers residing in State A. With respect to the sale...

  18. IDC Use Case Model Survey Version 1.1.

    Energy Technology Data Exchange (ETDEWEB)

    Harris, James Mark [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Carr, Dorthe B. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-02-01

    This document contains the brief descriptions for the actors and use cases contained in the IDC Use Case Model. REVISIONS Version Date Author/Team Revision Description Authorized by V1.0 12/2014 SNL IDC Reengineering Project Team Initial delivery M. Harris V1.1 2/2015 SNL IDC Reengineering Project Team Iteration I2 Review Comments M. Harris

  19. 26 CFR 1.1361-1 - S corporation defined.

    Science.gov (United States)

    2010-04-01

    ...) INCOME TAXES Small Business Corporations and Their Shareholders § 1.1361-1 S corporation defined. (a) In...)(2)) and that does not have— (i) More than the number of shareholders provided in section 1361(b)(1)(A); (ii) As a shareholder, a person (other than an estate, a trust described in section...

  20. 26 CFR 1.818-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... Revenue Code of 1954, as amended by the Life Insurance Company Income Tax Act of 1959 (73 Stat. 112). ... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Miscellaneous Provisions § 1.818-1 Taxable years affected. Sections 1.818-2 through...

  1. 26 CFR 1.810-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... amended by the Life Insurance Company Income Tax Act of 1959 (73 Stat. 112). ... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Gain and Loss from Operations § 1.810-1 Taxable years affected. Sections 1.810-2 through...

  2. 26 CFR 1.819-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... Insurance Company Income Tax Act of 1959 (73 Stat. 112). ... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Miscellaneous Provisions § 1.819-1 Taxable years affected. Section 1.819-2 is...

  3. 26 CFR 1.811-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... 1954, as amended by the Life Insurance Company Income Tax Act of 1959 (73 Stat. 112). ... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Gain and Loss from Operations § 1.811-1 Taxable years affected. Section 1.811-2, except...

  4. 26 CFR 1.809-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... Internal Revenue Code of 1954, as amended by the Life Insurance Company Income Tax Act of 1959 (73 Stat... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Gain and Loss from Operations § 1.809-1 Taxable years affected. Sections 1.809 through...

  5. 26 CFR 1.812-1 - Taxable years affected.

    Science.gov (United States)

    2010-04-01

    ... Internal Revenue Code of 1954, as amended by the Life Insurance Company Income Tax Act of 1959 (73 Stat... Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Gain and Loss from Operations § 1.812-1 Taxable years affected. Sections 1.812-2 through...

  6. Glucagon-like peptide 1 receptor agonist (GLP-1 RA)

    DEFF Research Database (Denmark)

    von Scholten, Bernt Johan; Hansen, Tine Willum; Goetze, Jens Peter;

    2015-01-01

    AIMS: In a short-term study including 31 patients with type 2 diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment was associated with a significant reversible decline in GFR. Twenty-three patients re-initiated GLP-1 RA treatment after the primary study, and the aim...

  7. A Toy Model of Quantum Electrodynamics in (1 + 1) Dimensions

    Science.gov (United States)

    Boozer, A. D.

    2008-01-01

    We present a toy model of quantum electrodynamics (QED) in (1 + 1) dimensions. The QED model is much simpler than QED in (3 + 1) dimensions but exhibits many of the same physical phenomena, and serves as a pedagogical introduction to both QED and quantum field theory in general. We show how the QED model can be derived by quantizing a toy model of…

  8. 26 CFR 1.514(g)-1 - Business lease indebtedness.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Business lease indebtedness. 1.514(g)-1 Section 1... Business lease indebtedness. (a) Definition. The term business lease indebtedness means, with respect to... subsidiary corporations. (b) Examples. The rules of section 514(g) respecting business leases also...

  9. 26 CFR 1.167(a)-1 - Depreciation in general.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Depreciation in general. 1.167(a)-1 Section 1... Depreciation in general. (a) Reasonable allowance. Section 167(a) provides that a reasonable allowance for the... the taxpayer for the production of income shall be allowed as a depreciation deduction. The...

  10. 26 CFR 1.167(g)-1 - Basis for depreciation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Basis for depreciation. 1.167(g)-1 Section 1.167... for depreciation. The basis upon which the allowance for depreciation is to be computed with respect... property at that time, is the basis for computing depreciation....

  11. 26 CFR 1.167(b)-1 - Straight line method.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Straight line method. 1.167(b)-1 Section 1.167(b... Straight line method. (a) In general. Under the straight line method the cost or other basis of the... may be reduced to a percentage or fraction. The straight line method may be used in determining...

  12. Type 1,1-operators defined by vanishing frequency modulation

    DEFF Research Database (Denmark)

    Johnsen, Jon

    2009-01-01

    singularities but only change their nature. The familiar rule that the support of the argument is transported by the support of the distribution kernel is generalised to arbitrary type 1,1-operators. A similar spectral support rule is also proved. As no restrictions appear for classical type 1,0-operators, this...

  13. ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes

    DEFF Research Database (Denmark)

    Hao, Qin; Hansen, Jacob B; Petersen, Rasmus K;

    2010-01-01

    regulatory element-binding protein-1c (SREBP1c) and peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC1alpha) in brown and inguinal white adipose tissues, but not in epididymal white adipose tissue. Using in vitro models of white and brown adipocytes we demonstrate that beta......Cold adaptation elicits a paradoxical simultaneous induction of fatty acid synthesis and beta-oxidation in brown adipose tissue. We show here that cold exposure coordinately induced liver X receptor alpha (LXRalpha), adipocyte determination and differentiation-dependent factor 1 (ADD1)/sterol...... as a regulator of PGC1alpha expression in brown adipose tissue....

  14. Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 {mu}1A (AP-1 mu1A)

    Energy Technology Data Exchange (ETDEWEB)

    Sawasdee, Nunghathai; Junking, Mutita [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Ngaojanlar, Piengpaga [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Department of Immunology and Graduate Program in Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Sukomon, Nattakan; Ungsupravate, Duangporn [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Limjindaporn, Thawornchai [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Akkarapatumwong, Varaporn [Institute of Molecular Biosciences, Mahidol University at Salaya Campus, Nakorn Pathom 73170 (Thailand); Noisakran, Sansanee [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand); Yenchitsomanus, Pa-thai, E-mail: grpye@mahidol.ac.th [Division of Medical Molecular Biology and BIOTEC-Medical Biotechnology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 (Thailand)

    2010-10-08

    Research highlights: {yields} Trafficking defect of kAE1 is a cause of dRTA but trafficking pathway of kAE1 has not been clearly described. {yields} Adaptor-related protein complex 1 {mu}1A (AP-1 mu1A) was firstly reported to interact with kAE1. {yields} The interacting site for AP-1 mu1A on Ct-kAE1 was found to be Y904DEV907, a subset of YXXO motif. {yields} AP-1 mu1A knockdown showed a marked reduction of kAE1 on the cell membrane and its accumulation in endoplasmic reticulum. {yields} AP-1 mu1A has a critical role in kAE1 trafficking to the plasma membrane. -- Abstract: Kidney anion exchanger 1 (kAE1) mediates chloride (Cl{sup -}) and bicarbonate (HCO{sub 3}{sup -}) exchange at the basolateral membrane of kidney {alpha}-intercalated cells. Impaired trafficking of kAE1 leads to defect of the Cl{sup -}/HCO{sub 3}{sup -} exchange at the basolateral membrane and failure of proton (H{sup +}) secretion at the apical membrane, causing a kidney disease - distal renal tubular acidosis (dRTA). To gain a better insight into kAE1 trafficking, we searched for proteins physically interacting with the C-terminal region of kAE1 (Ct-kAE1), which contains motifs crucial for intracellular trafficking, by a yeast two-hybrid (Y2H) system. An adaptor-related protein complex 1 {mu}1A (AP-1 mu1A) subunit was found to interact with Ct-kAE1. The interaction between either Ct-kAE1 or full-length kAE1 and AP-1 mu1A were confirmed in human embryonic kidney (HEK) 293T by co-immunoprecipitation, affinity co-purification, co-localization, yellow fluorescent protein (YFP)-based protein fragment complementation assay (PCA) and GST pull-down assay. The interacting site for AP-1 mu1A on Ct-kAE1 was found to be Y904DEV907, a subset of YXXO motif. Interestingly, suppression of endogenous AP-1 mu1A in HEK 293T by small interfering RNA (siRNA) decreased membrane localization of kAE1 and increased its intracellular accumulation, suggesting for the first time that AP-1 mu1A is involved in the kAE1

  15. Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 μ1A (AP-1 mu1A)

    International Nuclear Information System (INIS)

    Research highlights: → Trafficking defect of kAE1 is a cause of dRTA but trafficking pathway of kAE1 has not been clearly described. → Adaptor-related protein complex 1 μ1A (AP-1 mu1A) was firstly reported to interact with kAE1. → The interacting site for AP-1 mu1A on Ct-kAE1 was found to be Y904DEV907, a subset of YXXO motif. → AP-1 mu1A knockdown showed a marked reduction of kAE1 on the cell membrane and its accumulation in endoplasmic reticulum. → AP-1 mu1A has a critical role in kAE1 trafficking to the plasma membrane. -- Abstract: Kidney anion exchanger 1 (kAE1) mediates chloride (Cl-) and bicarbonate (HCO3-) exchange at the basolateral membrane of kidney α-intercalated cells. Impaired trafficking of kAE1 leads to defect of the Cl-/HCO3- exchange at the basolateral membrane and failure of proton (H+) secretion at the apical membrane, causing a kidney disease - distal renal tubular acidosis (dRTA). To gain a better insight into kAE1 trafficking, we searched for proteins physically interacting with the C-terminal region of kAE1 (Ct-kAE1), which contains motifs crucial for intracellular trafficking, by a yeast two-hybrid (Y2H) system. An adaptor-related protein complex 1 μ1A (AP-1 mu1A) subunit was found to interact with Ct-kAE1. The interaction between either Ct-kAE1 or full-length kAE1 and AP-1 mu1A were confirmed in human embryonic kidney (HEK) 293T by co-immunoprecipitation, affinity co-purification, co-localization, yellow fluorescent protein (YFP)-based protein fragment complementation assay (PCA) and GST pull-down assay. The interacting site for AP-1 mu1A on Ct-kAE1 was found to be Y904DEV907, a subset of YXXO motif. Interestingly, suppression of endogenous AP-1 mu1A in HEK 293T by small interfering RNA (siRNA) decreased membrane localization of kAE1 and increased its intracellular accumulation, suggesting for the first time that AP-1 mu1A is involved in the kAE1 trafficking of kidney α-intercalated cells.

  16. He{sup +} scattering on clean and oxygen covered Al(1 1 1)

    Energy Technology Data Exchange (ETDEWEB)

    Kravchuk, T. [Laboratoire des Collisions Atomiques et Moleculaires, UMR CNRS, Universite Paris, Sud No. 8625, bat. 351, Universite Paris Sud, 91405 Orsay Cedex (France); Department of Chemistry, Technion - Israel Institute of Technology, Haifa 32000 (Israel); Esaulov, V.A. [Laboratoire des Collisions Atomiques et Moleculaires, UMR CNRS, Universite Paris, Sud No. 8625, bat. 351, Universite Paris Sud, 91405 Orsay Cedex (France)]. E-mail: esaulov@lcam.u-psud.fr; Hoffman, A. [Department of Chemistry, Technion - Israel Institute of Technology, Haifa 32000 (Israel); Monreal, R.C. [Departamento de Fisica Teorica de la Materia Condensada C-V, Universidad Autonoma de Madrid, Cantoblanco, E-28049 Madrid (Spain)

    2005-05-01

    We present results of a study of He{sup +} neutralisation on clean and oxygen covered Al(1 1 1). For clean Al(1 1 1) we find a small ion fraction which rapidly increases with increasing ion energy attaining about (0.4 {+-} 0.1)% at 4 keV. The overall behaviour is quite different from that observed on previously studied Ag surfaces and is attributed to reionisation processes, a conclusion supported by measurements using He atoms. When O{sub 2} is adsorbed onto Al(1 1 1) at room temperature, we observe a rapid increase in the ion fraction, which attains a broad plateau for exposures higher than about 50 L. Experiments with incident He atoms lead to an ion fraction that is smaller, indicating that in this case a substantial fraction of ions is due to survival of incident ions. We attribute these changes to a decrease of the Auger neutralisation rates on the oxidic surface.

  17. Computer simulation of sputtering at the low index (1 0 0), (1 1 0) and (1 1 1) surfaces of Ni3Al in a STEM

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Wenshen; Yu, J. J.; Gao, Fei; Bacon, David J.

    2009-09-15

    The present study is relevant to the preferential Al sputtering and/or enhancement of the Ni/Al ratio in Ni3Al observed by the scanning transmission electron microscopy fitted with a field emission gun (FEG STEM). Atomic recoil events at the low index (1 0 0), (1 1 0) and (1 1 1) surfaces of Ni3Al through elastic collisions between electrons and atoms are simulated using molecular dynamics (MD) methods. The threshold energy for sputtering, Esp, and adatom creation, Ead, are determined as a function of recoil direction. Based on the MD determined Esp, the sputtering cross-sections for Ni and Al atoms in these surfaces are calculated with the previous proposed model. It is found that the sputtering cross-section for Al atoms is about 7–8 times higher than that for Ni, indicating the preferential sputtering of Al in Ni3Al, in good agreement with experiments. It is also found that the sputtering cross-sections for Ni atoms are almost the same in these three surfaces, suggesting that they are independent of surface orientation. Thus, the sputtering process is almost independent of the surface orientation in Ni3Al, as it is controlled by the sputtering of Ni atoms with a lower sputtering rate.

  18. Cretan(4t+1) Matrices

    OpenAIRE

    Balonin, N. A.; Seberry, Jennifer

    2015-01-01

    A $Cretan(4t+1)$ matrix, of order $4t+1$, is an orthogonal matrix whose elements have moduli $\\leq 1$. The only $Cretan(4t+1)$ matrices previously published are for orders 5, 9, 13, 17 and 37. This paper gives infinitely many new $Cretan(4t+1)$ matrices constructed using $regular~Hadamard$ matrices, $SBIBD(4t+1,k,\\lambda)$, weighing matrices, generalized Hadamard matrices and the Kronecker product. We introduce an inequality for the radius and give a construction for a Cretan matrix for every...

  19. [WEE1, histone and tumor].

    Science.gov (United States)

    Liu, Bin

    2015-07-01

    WEE1 is an important factor for histone transcription, chromosome condensation and regulation of cell cycle progression. WEE1 kinase can phosphorylate Cdc2 and down-regulate Cdc2 kinase activity. It can regulate G2 to M phase transition and cell mitosis. It plays a key role in chromosome condensation delay and histone synthesis, suggesting the important functions of WEE1 in the occurrence and development in cancer. At present, a multiple WEE1 inhibitors have been discovered. A great progress has been made in combination of WEE1 inhibitors with DNA damage treatment (chemotherapy or radiotherapy), which makes WEE1 an important target in cancer treatment. PMID:26267696

  20. The 1:1 adduct of caffeine and 2-(1,3-dioxoisoindolin-2-ylacetic acid

    Directory of Open Access Journals (Sweden)

    Moazzam H. Bhatti

    2011-09-01

    Full Text Available In the crystal structure of the title adduct [systematic name: 2-(1,3-dioxoisoindolin-2-ylacetic acid–1,3,7-trimethyl-1,2,3,6-tetrahydro-7H-purine-2,6-dione (1/1], C8H10N4O2·C10H7NO4, the components are linked by an O—H...N hydrogen-bond and no proton transfer occurs.