Crucible-Free Synthesis of Silicides and Borides; Synthese de siliciures et de borures sans creuset; Bestigel'nyj sintez silitsidov i boridov; Sintesis de siliciuros y boruros sin crisol

Energy Technology Data Exchange (ETDEWEB)

Ban, Z.; Sikirica, M. [Rudjer Boskovic Institute, Zagreb, Yugoslavia (Croatia)

1963-11-15

The laboratory method for preparing pure silicides and borides, reducing the corresponding oxides of metals, has been developed. Synthesis of silicides was carried out in the floating zone of molten silicon. The floating zone was obtained by means of electron bombardment. Synthesis of borides is similar but reactions are generally of the solid-solid type. Initial heating of the reaction mixture was also obtained by means of the electron beam but further heating was produced by the ionized gaseous products of the reaction. (author) [French] On a mis au point une methode pour la preparation en laboratoire de siliciures et de borures purs, par reduction des oxydes des metaux correspondants. La synthese des siliciures a pu etre faite dans la ''zone flottante'' du silicium fondu. Cette zone flottante a ete obtenue par bombardement electronique. La synthese des borures est analogue, mais les reactions ont lieu generalement a Tetat solide. Le chauffage initial du melange reactionnel a egalement ete obtenu pai bombardement electronique, mais le chauffage ulterieur etait assure par les electrons diffuses des produits ionises gazeux de la reaction. (author) [Spanish] Los autores idearon un metodo de laboratorio para preparar siliciuros y boruros puros por reduccion de los respectivos oxidos metalicos. La sintesis de los siliciuros se llevo a cabo en la zona flotante del silicio fundido. Esa zona se obtuvo por bombardeo electronico. La sintesis de los boruros se llevo a cabo de manera similar, pero generalmente las reacciones son del tipo solido-solido. El calentamiento inicial de la mezcla se efectuo tambien mediante un haz electronico, pero el calentamiento ulterior es producido por la dispersion electronica en los productos de reaccion ionizados en estado gaseoso. (author) [Russian] Razrabotan laboratornyj metod prigotovleniya chistykh silitsidov i boridov putem vosstanovleniya sootvetstvennykh okislov metalla. Sintez, silitsidov provodili v plavayushchej zone

Influência da estrutura do catalisador a base de Zirconoceno na estereorregularidade e propriedades do polipropileno formado Influence of Zirconocene structure on polypropylene stereorregularity and properties

Directory of Open Access Journals (Sweden)

Mário R. Meneghetti

1997-03-01

Full Text Available RESUMO: Catalisadores de metalocenos com diferentes simetrias, cocatalisados por metilaluminoxanas (MAO, foram avaliados em diferentes temperaturas de polimerização do propileno. Os metalocenos com ponte interanelar, ou seja, o dicloreto de rac-etileno bis(h5-1-indenil zircônio, com simetria C2, e o dicloreto de isopropilideno(h5-ciclopentadienil(h5-9-fluorenil zircônio, com simetria Cs, produziram, respectivamente, polipropileno isotático e sindiotático. O grau de taticidade desses polímeros diminui com o aumento da temperatura de polimerização. Os metalocenos sem ponte, dicloreto de bis(h5-ciclopentadienilzircônio e bis(h5-indenilzircônio, em qualquer uma das temperaturas investigadas, produziram, somente, polipropileno atático. A estereorregularidade dos polímeros foram determinadas por Ressonância Magnética Nuclear de 13C.ABSTRACT: Metallocenes with different symmetries in combination with methylaluminoxane (MAO, have been investigated at different propylene polymerization temperatures. The metallocenes rac-ethylene bis(h5-1-indenyl zirconium dichloride, with C2 symmetry and isopropylidene (h5cyclopentadienyl(h5-9-fluorenyl zirconium dichloride, with Cs symmetry, produce isotactic and syndiotactic polypropylene respectively. The degree of tacticity of these polymers decreases with the increase of polymerization temperature. Only atactic polypropylene was formed with the unbridged zirconocenes bis(h5-cyclopentadienyl zirconium dichloride and bis(h5-indenyl zirconium dichloride at any temperature investigated. The polymer microtacticity was analysed by 13C NMR.

SINTEZA BAKROVIH, NIKLJEVIH IN KOBALTOVIH KOORDINACIJSKIH SPOJIN Z NIKOTINSKO, IZONIKOTINSKO IN PIKOLINSKO KISLINO

OpenAIRE

Goljat, Leja

2013-01-01

Koordinacijske spojine so dandanes pogosto sintetizirane in imajo širok spekter uporabnosti. Namen raziskave je bil sintetizirati nove in že znane koordinacijske spojine z bakrom, kobaltom in nikljem. V sklopu diplomskega dela smo izvedli 27 reakcij sinteze koordinacijskih spojin z bakrom, kobaltom in nikljem ter ligandi nikotinsko, izonikotinsko in pikolinsko kislino. Kot topila smo uporabili vodo, N,N-dimetilformamid in mešanico metanola in acetonitrila. Produkte sintez smo nato analizirali...

Preparative Radiation Chemistry of Transition Metal Complexes; Radiosynthese de complexes de metaux de transition; Radiatsionno-khimicheskij sintez kompleksnykh soedinenij perekhodnykh metallov; Radiosintesis de complejos de los metales de transicion

Energy Technology Data Exchange (ETDEWEB)

Gustorf, E. Koerner Von; Jun, M. -J.; Koller, H.; Schenck, G. O. [Max-Planck-Institut fuer Kohlenforschung, Abteilung Strahlenchemie, Muelheim-Ruhr, Federal Republic of Germany (Germany)

1963-11-15

aktivnosti. Provedeny sleduyushchie issledovaniya: 1) Radiatsionno-khimicheskij sintez {pi}-kompleksov metallov peremennoj valentnosti. Primerom mozhet sluzhit' poluchenie kompleksov angidrid maleinovoj kisloty + tetrakarbonil zheleza, diametilovyj ehfir fumarovoj kisloty + tetrakarbonil zheleza, metilovyj ehfir metakrilovoj kisloty + tetrakarbonil zheleza, vinilatsetat + tetrakarbonil zheleza i t.d. pri gamma-obluchenii ot kobal'tovogo istochnika Fe(CO){sub 5} s sootvetstvuyushchimi nenasyshchennymi soedineniyami. 2) Khimicheskie reaktsii v sluchae {pi}-kompleksov, poluchennykh pri radiatsionno-khimicheskom sinteze. Primerom mozhet sluzhit' polimerizatsiya vinilovykh soedinenij pri komnatnoj temperature pod dejstviem organicheskikh galogenovykh soedinenij na takie kompleksy, kak metilovyj ehfir metakrilovoj kisloty - tetrakarbonil zheleza, vinilatsetat - tetrakarbonil zheleza i t.d. 3) Sintez {pi}-kompleksov i karbonil'nykh soedinenij metallov peremennoj valentnosti pri obluchenii. Primerom mozhet sluzhit' gamma-obluchenie ot istochnika Co{sup 60} v srede galogenovykh uglevodorodov sleduyushchikh {pi}-kompleksov: [(C{sub 5}H{sub 5}) Fe], [(C{sub 5}H{sub 5}){sub 2}Ni], CH{sub 3}C{sub 5}H{sub 4}Mn(CO){sub 3}, (C{sub 5}H{sub 5})TiCl{sub 2}, Fe(CO){sub 5}, Ni(CO){sub 4}.

Gross anatomy of the intestine and its mesentery in the nutria (Myocastor coypus).

Science.gov (United States)

Pérez, W; Lima, M; Bielli, A

2008-11-01

The intestines and mesentery of the nutria (Myocastor coypus) have not been fully described. In the present study 30 adult nutrias were studied using gross dissection. The small intestine was divided into the duodenum, jejunum and ileum as usual. The duodenum started at the pylorus with a cranial portion, which dilated forming a duodenal ampulla. The ileum was located within the concavity of the caecum and attached to the coiled caecum by means of the iliocaecal fold. The ascending colon had two ansae, one proximal and one distal. The proximal ansa was fixed to the caecum by the caecocolic fold. The base of the caecum and a short proximal part of the ascending colon belonging to the proximal ansa were attached to the mesoduodenum descendens. The distal ansa of the ascending colon had a proximal part which was sacculated and a distal part which was smooth. The two parts of the distal ansa of the ascending colon were parallel and joined by a flexure of variable localisation. The smooth part of the distal ansa of the ascending colon was attached to the initial portion of the descending colon by a peritoneal fold. The short transverse colon was directly attached to the mesoduodenum and greater omentum. In conclusion, we have described the anatomy of the intestines of the nutria and its mesentery in detail, and provided a nomenclature list adapted to the Nomina Anatomica Veterinaria.

Accessing OSI Managed Objects from ANSAware

OpenAIRE

Genilloud, Guy; Gay, David

1995-01-01

This paper presents a mechanism allowing an ODP compliant distributed system, ANSA, to access OSI network management objects as if they were ANSA objects. It defines a mapping from the OSI object model to the ANSA object model, and it specifies how an adapter implements this mapping.

On the location of the Io plasma torus: Voyager 1 observations

Directory of Open Access Journals (Sweden)

M. Volwerk

2018-06-01

Full Text Available The Voyager 1 outbound ultraviolet observations of the Io plasma torus are used to determine the location of the ansae, to obtain a third viewing angle of this structure in the Jovian magnetosphere. At an angle of −114° with respect to the Sun–Jupiter line, or a Jovian local time of 04:30 LT, the Voyager 1 data deliver a distance of 5.74±0.10 RJ for the approaching and 5.83±0.15 RJ for the receding ansa. Various periodicities in the radial distance, brightness and width of the ansae are seen with respect to system III longitude and Io phase angle. The torus ribbon feature does not appear in all ansa scans.

Analysis and Development of UAV Operations in the NAS, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Aurora Flight Sciences, in collaboration with Air Network Simulation and Analysis, Inc. (ANSA), proposes to develop a simulation-based methodology to analyze and...

ANS&A Equip-13 Dynamic Actuator

National Research Council Canada - National Science Library

Steedman, R

1996-01-01

The dynamic actuator is based on the principles of the stored angular momentum system for use in earthquake centrifuge modeling and is compatible with the Equivalent Shear Beam model container design...

Functional reinnervation of vocal folds after selective laryngeal adductor denervation-reinnervation surgery for spasmodic dysphonia.

Science.gov (United States)

DeConde, Adam S; Long, Jennifer L; Armin, Bob B; Berke, Gerald S

2012-09-01

Selective laryngeal adductor denervation-reinnervation surgery (SLAD-R) offers a viable surgical alternative for patients with adductor spasmodic dysphonia refractory to botulinum toxin injections. SLAD-R selectively denervates the symptomatic thyroarytenoid muscle by dividing the distal adductor branch of the recurrent laryngeal nerve (RLN), and preventing reinnervation, by the proximal RLN and maintaining vocal fold bulk and tone by reinnervating the distal RLN with the ansa cervicalis. We present a patient who had previously undergone successful SLAD-R but presented 10 years postoperatively with a new regional dystonia involving his strap muscles translocated to his reinnervated larynx by his previous ansa-RLN neurorraphy. The patient's symptomatic vocal fold adduction resolved completely on division of the ansa-RLN neurorraphy confirming successful selective functional reinnervation of vocal fold adductors by the ansa cervicalis. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

Observations on the macroscopic anatomy of the intestinal tract and its mesenteric folds in the pampas deer (Ozotoceros bezoarticus, Linnaeus 1758).

Science.gov (United States)

Pérez, W; Clauss, M; Ungerfeld, R

2008-08-01

We described the macroscopic anatomy of the intestines and their peritoneal folds of five adult pampas deer (Ozotoceros bezoarticus), a cervid species considered to ingest a high proportion of grass in its natural diet. The mean (+/-SD) body weight was 17 (+/-2) kg. The small intestine and the caecocolon measured 495 (+/-37) cm and 237 (+/-24) cm in length, respectively, with an average ratio (small intestine:caecocolon) of 1.9 (+/-0.1). The ascending colon had two and a half centripetal gyri, a central flexure and two centrifugal gyri. The spiral ansa, which was similar to an ellipse, was fixed to the whole left face of the mesenterium. Apart from the peritoneal folds described in the Nomina Anatomica Veterinaria, three additional, hitherto not described folds were found: a fold that fixed the caecum to the proximal ansa of the ascending colon, one that joined the terminal part of the proximal ansa to the last centrifugal gyrus of the spiral ansa of the ascending colon, and one that linked the ascending duodenum to the proximal ansa of the ascending colon. When compared with published data from other cervids of different feeding niches, it appears that, among cervids, the ratio of small intestine to the caecocolon length does not reflect the natural diet.

Olei̇n turşusunun ami̇dləri̇ni̇n sulfat TÖRƏMƏLƏRİNİN duzlarinin SİNTEZİ və məhlullarinin XASSƏLƏRİNİN TƏDQİQİ

OpenAIRE

N.Ş.Rzayeva

2014-01-01

Olein turşusunun N-dimetil, N-dietil, N-tsikloheksilamidləri sintez edilb və onların sulfat törəmələri alınıb. Daha sonra alınmış sulfat törəmələrinin Na, K və NH4 duzları sintez olunub. Duzların izopropil spirtinin suda 30%-li məhlulunda 20%-li məhlulları hazırlanıb və fiziki-kimyəvi xassələri öyrənılıb. Məhlulların sıxlıqları bir-birinə yaxın olub 0.9431-0.9579 qr/sm3 arasında dəyişir. Məhlulların donma temperaturları amid qrupunda olan N-alkildən asılı olaraq fərqlənir. Belə ki, N-dimetil ...

Im Gespräch: Postkoloniale Theorie und Intersektionalität

Directory of Open Access Journals (Sweden)

Stefan Wallaschek

2015-12-01

Full Text Available Postkoloniale Theorie und Intersektionalität gehören zu den wichtigsten Ansätzen der gegenwärtigen kritischen Sozialwissenschaften. Überraschenderweise scheint es kaum einen Dialog zwischen beiden Ansätzen zu geben. Ich versuche beide Ansätze in den Dialog zu bringen und analysiere sie vor dem Hintergrund der deutschsprachigen akademischen Debatte auf ihre Gemeinsamkeiten und Unterschiede. Zuerst gehe ich dabei auf die Arbeiten von Chandra Mohanty und Kimberlé Crenshaw ein. Während Erstere diskursanalytisch Arbeiten zu ‚Dritte-Welt-Frauen‘ untersucht und einen feministisch-postkolonialen Ansatz entwickelt, richtet Crenshaw ihren Blick auf die Verbindung von Geschlechter- und ‚race‘-Diskriminierung anhand von Gerichtsurteilen in den USA. Ich argumentiere, dass eine konstruktivistische Methodologie auf vier Knotenpunkten beruht und diese den Boden für den Dialog bereiten. In einem zweiten Schritt nutze ich diese für die intersektionale und postkoloniale Analyse der Arbeiten von Sojourner Truth und Clara Zetkin. Truth problematisiert eine gleichrangige Unterdrückung durch Geschlechter- und ‚race‘-Fragen, während Zetkin die hierarchische Unterdrückung durch die spezifische Klassenposition von Frauen hervorhebt. Eine Verbindung beider Ansätze wird im Fazit befürwortet, um Diskriminierungen und Ungerechtigkeiten in Zeiten neoliberaler kapitalistischer Hegemonie multidimensional zu erfassen.

L-Asparaginase from Streptomyces griseus NIOT-VKMA29: optimization of process variables using factorial designs and molecular characterization of L-asparaginase gene

Science.gov (United States)

Meena, Balakrishnan; Anburajan, Lawrance; Sathish, Thadikamala; Vijaya Raghavan, Rangamaran; Dharani, Gopal; Valsalan Vinithkumar, Nambali; Kirubagaran, Ramalingam

2015-07-01

Marine actinobacteria are known to be a rich source for novel metabolites with diverse biological activities. In this study, a potential extracellular L-asparaginase was characterised from the Streptomyces griseus NIOT-VKMA29. Box-Behnken based optimization was used to determine the culture medium components to enhance the L-asparaginase production. pH, starch, yeast extract and L-asparagine has a direct correlation for enzyme production with a maximum yield of 56.78 IU mL-1. A verification experiment was performed to validate the experiment and more than 99% validity was established. L-Asparaginase biosynthesis gene (ansA) from Streptomyces griseus NIOT-VKMA29 was heterologously expressed in Escherichia coli M15 and the enzyme production was increased threefold (123 IU mL-1) over the native strain. The ansA gene sequences reported in this study encloses several base substitutions with that of reported sequences in GenBank, resulting in altered amino acid sequences of the translated protein.

Effects of supported (nBuCp)2ZrCl2 catalyst active center multiplicity on crystallization kinetics of ethylene homo- and copolymers

KAUST Repository

Atiqullah, Muhammad; Adamu, Sagir; Hossain, Mohammad Mozahar; Al-Harthi, Mamdouh A.; Anantawaraskul, Siripon; Hossaen, Anwar

2014-01-01

Two different supported zirconocene, that is, bis(n-butylcyclopentadienyl) zirconium dichloride (nBuCp)2ZrCl2, catalysts were synthesized. Each catalyst was used to prepare one ethylene homopolymer and one ethylene-1-hexene copolymer. Catalyst

A catalytic and stoichiometric approach to the synthesis of the steroid B-ring en route to estratrienes

Czech Academy of Sciences Publication Activity Database

Herrmann, Pavel; Kotora, Martin

2007-01-01

Roč. 48, č. 18 (2007), s. 3209-3212 ISSN 0040-4039 R&D Projects: GA MŠk(CZ) LC06070 Institutional research plan: CEZ:AV0Z40550506 Keywords : zirconocene * dienes * cyclization * catalysis Subject RIV: CC - Organic Chemistry Impact factor: 2.615, year: 2007

Sinteza bakrovih, kobaltovih in nikljevih koordinacijskih spojin z izoniazidom

OpenAIRE

Hrastar, Sabina

2016-01-01

V diplomskem delu sem se ukvarjala s sintezo in karakterizacijo novih bakrovih, kobaltovih in nikljevih koordinacijskih spojin. Za sintezo smo uporabili bakrov acetat monohidrat, kobaltov acetat tetrahidrat in nikljev acetata tetrahidrat ter ligand izoniazid. Izvedli smo sedemdeset sinteznih reakcij, pri čemer smo spreminjali različne parametre: čas sinteze, temperaturo, topilo (destilirana voda, metanol, etanol, aceton, acetonitril, tetrahidrofuran, diklorometan, N,N-dimetilformamid) in post...

Solidarität und Heterogenität in Gruppen: Theoretische und empirische Skizzen

Directory of Open Access Journals (Sweden)

Irma Rybnikova

2015-03-01

Full Text Available Für gewöhnlich wird Heterogenität der Gruppen als Hindernis für Solidarität ihrer Mitglieder angesehen: Je verschiedener die Mitglieder, umso schwieriger kommt Solidarität zustande. In der vorliegenden Studie hinterfrage ich diese Generalisierung, indem ich eine Reihe von theoretischen Ansätzen aus der Soziologie und der Gruppenpsychologie konsultiere. Während einige dieser Ansätze nahelegen, dass Heterogenität der Mitglieder die Solidarität der Gruppen untergräbt, bestreiten dies andere Ansätze und gehen davon aus, dass auch heterogene Gruppen solidarisch sein können, vor allem dann, wenn unter den Mitgliedern eine Interdependenz vorliegt. Diese widersprüchlichen theoretischen Annahmen animierten mich zu einer empirischen Untersuchung von Studierendengruppen in einer Lehrveranstaltung. Die Ergebnisse zeigen zwar, dass zwischen Heterogenität und Solidarität in den interdependenten Gruppen ein Zusammenhang anzunehmen ist, dass jedoch auch eine Ambivalenz besteht zwischen individueller und Kollegensolidarität. Vor dem Hintergrund der theoretischen und empirischen Erkenntnisse diskutiere ich Schlussfolgerungen für die Forschung und für die praktischen Bemühungen der Solidarisierung im Bereich der gewerkschaftlichen Organisierung.

Impact of Nonselective Laryngeal Reinnervation on Main Voice Characteristics

Directory of Open Access Journals (Sweden)

V.A. Palamarchuck

2014-02-01

Results. The anastomosis of the RLN was performed in 95 patients, who were in the main group (53 patients with anastomosis ansa cervicalis — RLN, 34 patients with anastomosis RLN — RLN and 8 with anastomosis RLN — nerve-donor — RLN.The postoperative average follow-up was 12.0 ± 1.8 months and the median time to the first indirect evidence of reinnervation —4.5 ± 2.9 months, which were observed in all patients of the main group: the emergence of vocal fold tone, reducing the size of the glottis during phonation (especially at the anastomosis ansa cervicalis — RLN from 2.25 ± 0.86 mm to 0.35 ± 0.17 mm. Acoustic analysis showed the most effective reinnervation by the anastomosis ansa cervicalis — RLN, with change of HNR from 12.0 ± 3.7 dB to 24.0 ± 2.4 dB, MPT — from 7.00 ± 1.22 s to 16.00 ± 3.52 s (p < 0.01. The analysis of subjective psychosocial self-assessment of phonation showed the improvement in all subgroups of the main group.

The Beneficial Biological Properties of Salicylic Acid

Directory of Open Access Journals (Sweden)

Randjelović Pavle

2015-12-01

Full Text Available Salicilna kiselina je fitohemikalija sa povoljnim efektima na ljudsko zdravlje. Salicilna kiselina je fenolna komponenta i prisutna je u različitim biljkama, gde ima važnu ulogu u zaštiti od patogenih agenasa. U prirodi se nalazi u voću, povrću i začinima. Najpoznatiji i najbolje proučen efekat salicilne kiseline je inhibicija sinteze prostanglandina. Salicilna kiselina ostvaruje anti-zapaljensko dejstvo preko supresije gena za ciklooksigenazu. Većina farmakoloških svojstava salicilne kiseline mogu se objasniti inhibicijom sinteze prostanglandina. Otkriveno je da salicilna kiselina pored ovog ima i druga in vivo dejstva. Pošto salicilna kiselina ne inhibira značajno ciklooksigenazu, anti-zapaljensko dejstvo nije posledica direktne inhibicije ovog enzima. Predloženo je da je inhibicija nuklearnog faktora kapa B od strane salicilata jedno od glavnih mehanizama anti-zapaljenskog dejstva salicilata. Jedno od najviše proučavanih svojstava salicilne kiseline je antioksidativna aktivnost. Salicilna kiselina je dokazani inhibitor oksidativnog stresa. Salicilna kiselina ima sposobnost vezivanja gvožđa. Ova činjenica je značajna za antioksidativno dejstvo salicilne kiseline zbog toga što gvožđe ima važnu ulogu u procesu lipidne peroksidacije.

Stereoselectivity in metallocene-catalyzed coordination polymerization of renewable methylene butyrolactones: From stereo-random to stereo-perfect polymers

KAUST Repository

Chen, Xia; Caporaso, Lucia; Cavallo, Luigi; Chen, Eugene You Xian

2012-01-01

Coordination polymerization of renewable α-methylene-γ-(methyl) butyrolactones by chiral C 2-symmetric zirconocene catalysts produces stereo-random, highly stereo-regular, or perfectly stereo-regular polymers, depending on the monomer and catalyst structures. Computational studies yield a fundamental understanding of the stereocontrol mechanism governing these new polymerization reactions mediated by chiral metallocenium catalysts. © 2012 American Chemical Society.

Stereoselectivity in metallocene-catalyzed coordination polymerization of renewable methylene butyrolactones: From stereo-random to stereo-perfect polymers

KAUST Repository

Chen, Xia

2012-05-02

Coordination polymerization of renewable α-methylene-γ-(methyl) butyrolactones by chiral C 2-symmetric zirconocene catalysts produces stereo-random, highly stereo-regular, or perfectly stereo-regular polymers, depending on the monomer and catalyst structures. Computational studies yield a fundamental understanding of the stereocontrol mechanism governing these new polymerization reactions mediated by chiral metallocenium catalysts. © 2012 American Chemical Society.

Application of Tritiated Compounds to the Midge Chironomus and some Aspects of the Metabolism of Salivary Gland Chromosomes; Emploi de Composes Trities pour l'Etude du Chironome et de Certains Aspects du Metabolisme des Chromosomes des Glandes Salivaires; 041f 0440 0438 043c 0414 ; Aplicacion de Compuestos Tritiados a la Mosca Cbironomus y Algunos Aspectos del Metabolismo en los Cromosomas de las Glandulas Salivares

Energy Technology Data Exchange (ETDEWEB)

Pelling, C. [Max-Planck-Institut fuer Biologie, Tuebingen, Federal Republic of Germany (Germany)

1962-02-15

vysokoj stepen'ju razdelenija. Sintez DNK (timidin), sintez RNK (uridin) i proteinovyj sintez v kletke mozhno prosledit' putem opredelenija vremeni i priblizitel'- nogo kolichestva pogloshhenija. V protivopolozhnost' proteinovomu sintezu sintez-DNK i sintez RNK javlja- jutsja ogranichennymi dlja hromosom. Sushhestvennaja fiziologicheskaja aktivnost' hromosom, vidimo, predstavlena sintezom RNK, kotoryj imeet mesto pri opre- delennyh otchetlivyh mestopolozhenijah (nukleoljarnye obrazovateli, kol'ca 'Balbiani' odutlovatosti i drugie hromosomye svjazi). I doklade rassmatrivajutsja nekotorye osobennosti sinteza NIK. (author)

Investigations of food irradiation technology in Japan

International Nuclear Information System (INIS)

2009-01-01

All Nippon Spice Assoc. (ANSA) requested the approval in the Ministry of Health Labour and Welfare (MHLW) of radiation irradiation of their products for sterilization and pesticide in 2000. Problems of food irradiation (FI) which started from this ANSA request have been investigated by concerned Japanese administrations and associations with reference to trends in foreign countries, and of which outline till Aug., 2009 is described in this paper. On ANSA petition, AEC (Atomic Energy Committee) required the investigation of the safety problem in FI as it matched AEC policy and there have been background problems of Japanese people who have been having refusal response to radiation themselves. In 2003, Food Safety Committee (FSC) started, and AEC radiation expert committee investigated the trend and detection methodology of irradiated foods. Next year, FSC approved the irradiation of potato to prevent budding; MHLW began to study the detection methodology; and AEC mentioned to consider the FI problem in the Cabinet meeting and set up its expert committee (2005). MHLW reported the above decision in Councils of food/drug and of food hygiene (2006), published the methodology (thermoluminescence method) and started to monitor spices; and FSC discussed about FI problems with World Health Organization (WHO) experts (2007). During these years, the administrations trusted various investigations like foreign trends, safety and assessment of FI. In 2009, MHLW published results of their trusted investigations, based on which food hygienic and standardization sections began to investigate the problems; and FSC, the toxicity study of alkylcyclobutanone. During the period later than 2007, not only spices but also other foods like dried vegetables, tea, certain farm and marine products have been subject to monitoring (MHLW). Thus, MHLW has taken a leading role in actual approval of irradiated potato and in monitoring of imported foods. (K.T.)

RESULTS OF AN OPEN-LABEL COMPARATIVE RANDOMIZED CLINICAL TRIAL OF AXOGLATIRAN® FS (F-SINTEZ, RUSSIA EFFICIENCY AND SAFETY IN COMPARISON WITH COPAXONE®-TEVA (TEVA PHARMACEUTICAL INDUSTRIES LTD., ISRAEL IN PATIENTS WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS

Directory of Open Access Journals (Sweden)

F. A. Khabirov

2016-01-01

Full Text Available Objective. Comparison of Axoglatiran® FS (F-Sintez,  Russia and Copaxone®-Teva (Teva Pharmaceutical Industries Ltd.,  Israel efficiency and safety in patients with relapsing-remitting multiple sclerosis. Materials and methods. In the study 150 patients with relapsing-remitting multiple sclerosis were randomized into 2 groups: patients in the 1st group (n = 100 received treatment with Axoglatiran® FS, patients in the 2nd group (n = 50 received treatment with Copaxone®-Teva. Vital signs of every patient in the study were monitored accompanied by physical examinations, neurological examinations with EDSS (Expanded Disability Status Scale and MSFC (Multiple Sclerosis Functional Composite evaluations, magnetic resonance imaging of the brain and lab tests. Results. Mean age (M ± SD of the patients in the 1st group was 32.8 ± 8.7 years (20–54  years, percentages of men and women were 34 and 66 % respectively, mean age of multiple sclerosis onset was 27.93 ± 7.72 years (11–48 years. Median (Me, lower and upper quartiles estimates [LQ; UQ] on the EDSS scale were 2 [1.5; 3.0] steps (1.0–4.5  steps. In the 2nd group mean age of the patients was 35.2 ± 9.5 years (18–57  years, percentages of men and women were 24 and 76 % respectively, mean age of multiple sclerosis onset was 26.5 ± 6.9 years (18–47  years, EDSS estimates were 2.25 [1.5; 3.5] steps (1–5  steps. In the 1st group 88 (88 % patients completed the study, in the 2nd  group 44 (88 % patients completed the study. Among them in 73 (82.95 % patients in the 1st group and 34 (77.27 % patients in the 2nd  group the disease didn’t exacerbate (p > 0.05. In both groups no progression according to the EDSS and MSFC scale was observed (p > 0.05. Magnetic resonance imaging data showed that dynamics of the total number of T2 lesions, contrast-enhancing T1 lesions, atrophy degree estimated using internuclear index were comparable in both groups (p > 0.05. Safety profiles of

Towards engagement, compliance and accountability

Directory of Open Access Journals (Sweden)

Annyssa Bellal

2011-03-01

Full Text Available The UN and other international and regional organisations are increasingly trying to hold armed non-state actors (ANSAs accountable at the international level for violations of international norms....

Mexico attempts to tackle obesity: the process, results, push backs and future challenges.

Science.gov (United States)

Barquera, S; Campos, I; Rivera, J A

2013-11-01

Mexico's obesity prevalence is one of the world's highest. In 2006, academics, and federal and state government agencies initiated efforts to design a national policy for obesity prevention. The Ministry of Health (MOH) established an expert panel to develop recommendations on beverage intake for a healthy life in 2008. Subsequently, the MOH, with support from academia, initiated the development of the National Agreement for Healthy Nutrition (ANSA). ANSA was signed by all relevant sectoral actors in 2010 and led to initiatives banning sodas and regulating unhealthy food in schools and the design of other yet to be implemented initiatives, such as a front-of-package labeling system. A main challenge of the ANSA has been the lack of harmonization between industry interests and public health objectives and effective accountability and monitoring mechanisms to assess implementation across government sectors. Bold strategies currently under consideration include taxation of sugar-sweetened beverages, improvement of norms for healthy food in schools, regulation of food and beverage marketing to children and implementation of a national front-of-pack labeling system. Strong civil society organizations have embraced the prevention of obesity as their goal and have used evidence from academia to position obesity prevention in the public debate and in the government agenda. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

Synthesis of Ethylene or Propylene/1,3-Butadiene Copolymers Possessing Pendant Vinyl Groups with Virtually No Internal Olefins

OpenAIRE

Kenji Michiue; Makoto Mitani; Terunori Fujita

2015-01-01

In general, ethylene/1,3-butadiene copolymerizations provides copolymers possessing both pendant vinyls and vinylenes as olefinic moieties. We, at MCI, studied the substituent effects of C2-symmetric zirconocene complexes, rac-[Me2Si(Indenyl’)2]ZrCl2 (Indenyl’ = generic substituted indenyl), after activation on the ratio of the pendant vinyls and vinylenes of the resultant copolymers. Complexes examined in this study were rac-dimethylsilylbis (1-indenyl)zirconium dichloride (1), rac-dimethyls...

Commissioning (Phases 4, 4A, 4B)

National Research Council Canada - National Science Library

Schofield, Andrew

1997-01-01

Phase 4 marked the completion of ANS&A's commitments under the BAA, as the new large centrifuge at the Waterways Experiment Station was commissioned and a series of research experiments were undertaken to demonstrate the breadth of new...

On neutrino and charged lepton masses and mixings: a view from the electroweak-scale right-handed neutrino model

Energy Technology Data Exchange (ETDEWEB)

Hung, P.Q.; Le, Trinh [Department of Physics, University of Virginia,Charlottesville, VA 22904-4714 (United States)

2015-09-01

We present a model of neutrino masses within the framework of the EW-ν{sub R} model in which the experimentally desired form of the PMNS matrix is obtained by applying an A{sub 4} symmetry to the Higgs singlet sector responsible for the neutrino Dirac mass matrix. This mechanism naturally avoids potential conflict with the LHC data which severely constrains the Higgs sector, in particular the Higgs doublets. Moreover, by making a simple ansa{sup ¨}tz we extract M{sub l}M{sub l}{sup †} for the charged lepton sector. A similar ansa{sup ¨}tz is proposed for the quark sector. The sources of masses for the neutrinos are entirely different from those for the charged leptons and for the quarks and this might explain why U{sub PMNS} is very different from V{sub CKM}.

Case report

African Journals Online (AJOL)

16 oct. 2012 ... The Pan African Medical Journal - ISSN 1937-8688. This is ... Dawson et Langman ont appelé ansa pancréatica la formation dans laquelle une ... Kamisawa T, Koibe M, Okamoto A. Embryology of the pancreatic duct system.

Synthesis of methyl 3-O-{alpha}-d-glucopyranosyl-C{sub 6}{sup 14}-{beta}-d-xylopyranoside and methyl 2-O-{alpha}-d-Glucopyranosyl-C{sub 6}{sup 14}-l-noviopyranoside; Synthese de methyl-3-O-alpha-D-glucopyranosyl-C{sup 14}-beta-D-xylophranoside et methyl-2-O-alpha-D-glucopyranosyl-C{sub 6}{sup 14}-L-noviopyranoside; Sintez metil-3-O-{alpha}-D-glyukopiranozila-C{sub 6}{sup 14}-{beta}-D-ksilopiranozid i metil 2-O-{alpha}-D-glyukopiranozil-C{sub 6}{sup 14}-L-noviopiranozid; Sintesis de la metil 3-O-{alpha}-D-glucopiranosil-{sup 14}C{sub 6}-{beta}-D-xilopiranosido y de la metil 2-O-{alpha}-D-glucopiranosil-{sup 14}C{sub 6}-L-noviopiranosido

Energy Technology Data Exchange (ETDEWEB)

Barker, S A; Keith, M C; Stacey, M; Stroud, D B.E. [Chemistry Department, University of Birmingham (United Kingdom)

1962-03-15

microbianas. Como ejemplo de la aplicacion de esta tecnica, los autores describen las sintesis siguientes: Maltosa-{sup 14}C{sub 12} + metil-{beta}-D-xilopiranosido Transglucosilasa del/Penicillium lilacinum {yields} Metil 3-O-{alpha}-D-glucopiranosil-{sup 14}C{sub 6}-{beta}-D-xilopiranosido (I) Glucosa-{sup 14}C{sub 6} Maltosa-{sup 14}C{sub 12} + Metil L-noviopiranosido Transglucosilasa del/Fusarium moniliforme {yields} Metil 2-O-{alpha}-D-glucopiranosil-{sup 14}C{sub 6}-L-noviopiranosido (II) + Glucosa-{sup 14}C{sub 6}. Se puede esperar que en estas sintesis se conserve en el disacarico obtenido por sintesis el caracter anomerico del enlace glucosidico del disacarido donor y que el resto glucosido transferido se una por su grupo reductor al glucomonosacarido receptor. Si se emplea un disacarido donor o un glucosido receptor marcados con {sup 14}C, se puede sintetizar un disacarido mareado solamente en uno de los dos azucares que lo componen. En la sintesis del compuesto II, el unico grupo oxhidrilo libre en el metilnoviosido receptor se encuentra en el C{sub 2} y el resto glucosido que se transfiere solo puede unirse en ese punto. En la sintesis del compuesto I, el metilxilosido posee grupos oxhidrilo libres en C{sub 2}, C{sub 3} y C{sub 4}, y se ha encontrado que la enzima microbiana transfiere el resto glucosido especificamente al grupo oxhidrilo en el C{sub 3}. Se han determinado las estructuras de los compuestos I y II por analisis elemental, asi como por estudio de la actividad optica de los espectros infrarrojos y de los productos obtenidos por hidrolisis en medio acido y por oxidacion con peryodato. (author) [Russian] V sluchae zatrudneniya provedeniya khimicheskogo sinteza disakharida glikozida, mechennogo uglerodom-14, osobenno tol'ko v odnoj iz grupp sakhara chasto tselesoobrazno ispol'zovat' katalizirovannyj sintez s pomoshch'yu mikrobial'nogo transglikozilasa. V doklade soobshchaetsya o dvukh primerakh ispol'zovaniya dannogo metoda: Mal'toza-C{sub 12}{sup 14

13C and 15N CP/MAS, 1H-15N SCT CP/MAS and FTIR spectroscopy as tools for qualitative detection of the presence of zwitterionic and non-ionic forms of ansa-macrolide 3-formylrifamycin SV and its derivatives in solid state.

Science.gov (United States)

Przybylski, Piotr; Pyta, Krystian; Klich, Katarzyna; Schilf, Wojciech; Kamieński, Bohdan

2014-01-01

(13)C, (15)N CP/MAS, including (1)H-(13)C and (1)H-(15)N short contact time CP/MAS experiments, and FTIR methods were applied for detailed structural characterization of ansa-macrolides as 3-formylrifamycin SV (1) and its derivatives (2-6) in crystal and in powder forms. Although HPLC chromatograms for 2/CH3 OH and 2/CH3 CCl3 were the same for rifampicin crystals dissolved in respective solvents, the UV-vis data recorded for them were different in 300-375 nm region. Detailed solid state (13)C and (15)N CP/MAS NMR and FTIR studies revealed that rifampicin (2), in contrast to 3-formylrifamycin SV (1) and its amino derivatives (3-6), can occur in pure non-ionic or zwitterionic forms in crystal and in pure these forms or a mixture of them in a powder. Multinuclear CP/MAS and FTIR studies demonstrated also that 3-6 derivatives were present exclusively in pure zwitterionic forms, both in powder and in crystal. On the basis of the solid state NMR and FTIR studies, two conformers of 3-formylrifamycin SV were detected in powder form due to the different orientations of carbonyl group of amide moiety. The PM6 molecular modeling at the semi-empirical level of theory, allowed visualization the most energetically favorable non-ionic and zwitterionic forms of 1-6 antibiotics, strongly stabilized via intramolecular H-bonds. FTIR studies indicated that the originally adopted forms of these type antibiotics in crystal or in powder are stable in standard laboratory conditions in time. The results presented point to the fact that because of a possible presence of two forms of rifampicin (compound 2), quantification of the content of this antibiotic in relevant pharmaceuticals needs caution. Copyright © 2013 John Wiley & Sons, Ltd.

ISTRAŽIVANJE KARAKTERISTIKA KLASIČNE ŠKOLE STRATEŠKOG MENADŽMENTA U PODUZEĆIMA PRIMORSKO-GORANSKE ŽUPANIJE

OpenAIRE

Jelenc, Lara

2005-01-01

Znanstvenici i menadžeri proces strateškog menadžmenta promatraju, kao osnovni predmet izučavanja strateškog menadžmenta, na disperzan i pomalo kontradiktoran način. Različito pristupaju osmišljavanju procesa strateškoga menadžmenta, stvarajući mnogobrojne kombinacije, sugestije i nudeći recepte uspjeha strategija u praksi. Osim toga, postoje i različiti pogledi na razvitak discipline strateškog menadžmenta. Škole strateškog menadžmenta, osobito klasična škola, pokušaji su sinteze tih ideja i...

Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.

Directory of Open Access Journals (Sweden)

Alexandre Gouzy

2014-02-01

Full Text Available Mycobacterium tuberculosis is an intracellular pathogen. Within macrophages, M. tuberculosis thrives in a specialized membrane-bound vacuole, the phagosome, whose pH is slightly acidic, and where access to nutrients is limited. Understanding how the bacillus extracts and incorporates nutrients from its host may help develop novel strategies to combat tuberculosis. Here we show that M. tuberculosis employs the asparagine transporter AnsP2 and the secreted asparaginase AnsA to assimilate nitrogen and resist acid stress through asparagine hydrolysis and ammonia release. While the role of AnsP2 is partially spared by yet to be identified transporter(s, that of AnsA is crucial in both phagosome acidification arrest and intracellular replication, as an M. tuberculosis mutant lacking this asparaginase is ultimately attenuated in macrophages and in mice. Our study provides yet another example of the intimate link between physiology and virulence in the tubercle bacillus, and identifies a novel pathway to be targeted for therapeutic purposes.

Rethinking Disarmament, Demobilization and Reintegration Programs

Directory of Open Access Journals (Sweden)

Jairo Munive

2015-10-01

Full Text Available This article introduces the special issue on DDR and ‘Armed Non-Statutory Actors’ (ANSAs which we prefer to the less precise label of Armed Non-State Actors. The understanding that disarmament, demobilization and reintegration (DDR programs are essential in helping to prevent the recurrence of war in post-conflict situations is at the heart of current peacebuilding practice and the academic literature on peacekeeping and stabilization. But the changing strategic context of DDR programs and in particular the proliferation of ANSAs presents new challenges, the responses to which have been characterized as ‘second generation’ DDR. The changing context poses new questions and forces us to rethink assumptions and templates of DDR as the concept is blurred and expanded. The question is if it makes sense to hold on to the concept or whether the assumptions associated with it will get in the way of rethinking templates for violence reduction in the future.

Grafikos ir knygos sintezė. Iliustracijų knyga - "Laiko pasaka"

OpenAIRE

Plieniūtė, Rasa

2006-01-01

The length of human life is compared with a book. The closed book shows the end of life. To me a book is the source of inspiration, imagination and intention. Some time after reading a book I get a lot of impulses for my new creations. My book of illustrations ”The Tale of Time” is a book about the everlasting circle of life. My book has no reading function as a normal book. The meaning of my book “The Tale of Time” is expressed visually through my emotions about the temporality of human life...

Augimo reguliatoriaus trineksapak-etilo ir jo mišinių įtaka žieminių kviečių stiebų biometriniams rodikliams

OpenAIRE

Auškalnienė, Ona

2005-01-01

Augimo reguliatoriai naudojami javų išgulimui išvengti ir užima svarbią vietą javų auginimo technologijoje. Augimo reguliatorių bei jų mišinių ir derinių efektyvumo tyrimai daryti 2002-2003 metais Lietuvos žemdirbystės instituto Dirvožemio ir augalininkystės skyriaus sėjomainų žieminių kviečių 'Širvinta' laukuose. Dirvožemis - giliau karbonatingas sekliau glėjiškas rudžemis, lengvas priemolis, drenuotas, neutralaus rūgštumo. Žieminiai kviečiai purkšti giberalinu sintezės inhibitoriais cykocel...

Managing ANSA Objects with OSI Network Management Tools

OpenAIRE

Polizzi, Marc; Genilloud, Guy

1995-01-01

OSI Network Management provides a general framework for the management of OSI systems, and by extension of any distributed system. However, as this model is not well-adapted for the management of software components, distributed programming environments (e.g. DCE, CORBA, ANSAware) essentially ignore the OSI Network Management model. We assume nevertheless that OSI Network managers will want to have some control of a distributed infrastructure and application. We examine how access to some of ...

Author Details

African Journals Online (AJOL)

Ansa-Asare, O. Vol 13, No 1 (2008) - Articles Total petroleum content and polycyclic aromatic hydrocarbon levels in soil and groundwater at the site of a fuel service station in Accra. Abstract. ISSN: 0855-2215. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More ...

Hidrotermālās apstrādes procesa ietekme uz Ca un Sr hidroksilapatītiem un to analīze

OpenAIRE

Aksjonova, Viktorija

2015-01-01

Hidrotermālās apstrādes procesa ietekme uz Ca un Sr hidroksilapatītiem un to analīze. Aksjonova V., zinātniskā vadītāja: docente Dr.chem. Osīte A.. Bakalaura darbs, 28 lpp., 7 attēli, 25 literatūras avoti, 6 pielikumi, latviešu valodā. Darbā veikta ar stronciju aizvietotu hidroksilapatītu un hidroksilapatītu sintēze, sintezēto paraugu hidrotermāla apstrāde un iegūto paraugu raksturošana ar XRD un FTIR metodēm. Bakalaura darbā apkopota literatūra par hidroksilapatītu, stroncija hidrok...

Proceedings of the Systems Reengineering Technology Workshop (4th) held in Monterey, California on February 8 - 10, 1994

Science.gov (United States)

1994-09-01

models (r) constraints The FODA method of domain analysis and the Synthesis method follow a top down, problem oriented Analysis of problem domain...34Advanced Network Systems Architecture (ANSA) Analysis ( FODA ) to the Army Movement Control Domain", Manual", Architecture Projects Management Ltd...Ada Noah Prywes, Giorgio Ingargiola, Insup Lee, and Moon Lee (Computer Command and Control Company ) ............................ 157 Software Migration

Zirconacyclopentadiene-annulated polycyclic aromatic hydrocarbons

International Nuclear Information System (INIS)

Kiel, Gavin R.; Ziegler, Micah S.; Tilley, T. Don

2017-01-01

Syntheses of large polycyclic aromatic hydrocarbons (PAHs) and graphene nanostructures demand methods that are capable of selectively and efficiently fusing large numbers of aromatic rings, yet such methods remain scarce. Herein, we report a new approach that is based on the quantitative intramolecular reductive cyclization of an oligo(diyne) with a low-valent zirconocene reagent, which gives a PAH with one or more annulated zirconacyclopentadienes (ZrPAHs). The efficiency of this process is demonstrated by a high-yielding fivefold intramolecular coupling to form a helical ZrPAH with 16 fused rings (from a precursor with no fused rings). Several other PAH topologies are also reported. Protodemetalation of the ZrPAHs allowed full characterization (including by X-ray crystallography) of PAHs containing one or more appended dienes with the ortho-quinodimethane (o-QDM) structure, which are usually too reactive for isolation and are potentially valuable for the fusion of additional rings by Diels-Alder reactions. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

Zirconacyclopentadiene-annulated polycyclic aromatic hydrocarbons

Energy Technology Data Exchange (ETDEWEB)

Kiel, Gavin R.; Ziegler, Micah S.; Tilley, T. Don [Department of Chemistry, University of California, Berkeley, CA (United States)

2017-04-18

Syntheses of large polycyclic aromatic hydrocarbons (PAHs) and graphene nanostructures demand methods that are capable of selectively and efficiently fusing large numbers of aromatic rings, yet such methods remain scarce. Herein, we report a new approach that is based on the quantitative intramolecular reductive cyclization of an oligo(diyne) with a low-valent zirconocene reagent, which gives a PAH with one or more annulated zirconacyclopentadienes (ZrPAHs). The efficiency of this process is demonstrated by a high-yielding fivefold intramolecular coupling to form a helical ZrPAH with 16 fused rings (from a precursor with no fused rings). Several other PAH topologies are also reported. Protodemetalation of the ZrPAHs allowed full characterization (including by X-ray crystallography) of PAHs containing one or more appended dienes with the ortho-quinodimethane (o-QDM) structure, which are usually too reactive for isolation and are potentially valuable for the fusion of additional rings by Diels-Alder reactions. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

Design of the WES Centrifuge (Phase 3A and 3B)

Science.gov (United States)

1993-03-31

the facility; heme ANS&A’a role was to encourage users from different laboratories by discussing the opportunities that presented themselves on the...the ability to interpret users’ needs and for conceptual model defintion , den aquisition and mastrking. Possible arrangements whereby RP could spend...equipment was discussed. CRREL involvement would be needed in the defintion of initial experiments and in the devdlopme of a programme for the commismoning

Stable SU(5) monopoles with higher magnetic charge

International Nuclear Information System (INIS)

Miyamoto, S.; Sato, H.; Tomohiro, S.

1985-01-01

Taking into account the electroweak breaking effects, some multiply charged monopoles were shown to be stable by Gardner and Harvey. We give the explicit Ansa$uml: tze for finite-energy, nonsingular solutions of these stable higher-strength monopoles with eg = 1,(3/2),3. We also give the general stability conditions and the detailed behavior of the interaction potentials between two monopoles which produce the stable higher-strength monopoles

Effect of Mn doped-titania on the activity of metallocene catalyst by in situ ethylene polymerization

KAUST Repository

Abdul Kaleel, S. H.

2012-09-01

Ethylene polymerization was carried out using highly active metallocene catalysts (Cp 2ZrCl 2 and Cp 2TiCl 2) in combination with methylalumoxane. Titanium(IV) oxide containing 1% Mn as dopant was used as nanofillers. The influence of filler concentration, reaction temperature and pressure on the catalytic activity and polymer properties was investigated. There was a fourfold increase in the activity of zirconocene catalyst by addition of doped-titania. The morphology indicates that the doped-titania nanoparticles have a nucleus effect on the polymerization and caused a homogeneous PE shell around them. The optimum condition for polymerization was found to be 30°C. © 2012 The Korean Society of Industrial and Engineering Chemistry.

Sammelbesprechung: Sandor S. Feldman (1959). Mannerisms of Speech and Gestures in Everyday Life / David McNeill (Hrsg.) (2000). Language and Gesture / Jan Bremmer & Herman Rooddenburg (Hrsg.) (1991). A Cultural History of Gesture. From Antiquity to t

OpenAIRE

Buchholz, Michael B.

2002-01-01

Sprache und Gestik werden traditionell getrennt gesehen (verbales und averbales Verhalten). Neuere Ansätze jedoch erkennen ihre unauflösliche Verbundenheit an und sehen Sprache und Gestik als "Körpern in Interaktion" hervorgebracht. Das fordert zu einem völlig neuen Verständnis von beidem heraus. Ich versuche an die älteren Arbeiten des Psychoanalytikers Sandor S. FELDMAN zu erinnern, der gestische Manierismen seiner Patienten beobachtete und sie als Zugang zu ihren seelischen Konflikten ansa...

Sammelbesprechung: Sandor S. Feldman (1959). Mannerisms of Speech and Gestures in Everyday Life / David McNeill (Hrsg.) (2000). Language and Gesture / Jan Bremmer & Herman Rooddenburg (Hrsg.) (1991). A Cultural History of Gesture. From Antiquity to the Present Day / Jean-Claude Schmitt (1992). Die Logik der Gesten im europäischen Mittelalter

OpenAIRE

Buchholz, Michael B.

2002-01-01

Sprache und Gestik werden traditionell getrennt gesehen (verbales und averbales Verhalten). Neuere Ansätze jedoch erkennen ihre unauflösliche Verbundenheit an und sehen Sprache und Gestik als "Körpern in Interaktion" hervorgebracht. Das fordert zu einem völlig neuen Verständnis von beidem heraus. Ich versuche an die älteren Arbeiten des Psychoanalytikers Sandor S. FELDMAN zu erinnern, der gestische Manierismen seiner Patienten beobachtete und sie als Zugang zu ihren seelischen Konflikten ansa...

Copolymerization of propene and styrene using a zirconocene - methylaluminoxane initiator system

International Nuclear Information System (INIS)

Rabagliati, F.M.; Rodriguez, F.J.; Quijada, R.; Galland, G.B.

2009-01-01

The copolymerization of propene with styrene has been tested using the rac-Et(Ind) 2 ZrCl 2 -methylaluminoxane initiator system. The various proportion of styrene in initial feed showed an important effect on the polymerization activity. Low contents of styrene in the reaction produced a considerable fall in the activity. Respect to thermal behavior, it is noted that obtained propene/styrene copolymers showed Tm values slightly lower than the corresponding polypropene one. NMR spectroscopy allowed to confirm that the copolymer composition includes a very low incorporation of styrene in polypropylene chains. (author)

Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice.

Science.gov (United States)

Shusterman, Vladimir; Usiene, Irmute; Harrigal, Chivonne; Lee, Joon Sup; Kubota, Toru; Feldman, Arthur M; London, Barry

2002-06-01

Transgenic mice are widely used to study cardiac function, but strain-dependent differences in autonomic nervous system activity (ANSA) have not been explored. We compared 1) short-term pharmacological responses of cardiac rhythm in FVB vs. C57Black6/SV129 wild-type mice and 2) long-term physiological dynamics of cardiac rhythm and survival in tumor necrosis factor (TNF)-alpha transgenic mice with heart failure (TNF-alpha mice) on defined backgrounds. Ambulatory telemetry electrocardiographic recordings and response to saline, adrenergic, and cholinergic agents were examined in FVB and C57Black6/SV129 mice. In FVB mice, baseline heart rate (HR) was higher and did not change after injection of isoproterenol or atropine but decreased with propranolol. In C57Black6/SV129 mice, HR did not change with propranolol but increased with isoproterenol or atropine. Mean HR, but not indexes of HR variability, was an excellent predictor of response to autonomic agents. The proportion of surviving animals was higher in TNF-alpha mice on an FVB background than on a mixed FVB/C57Black6 background. The homeostatic states of ANSA are strain specific, which can explain the interstrain differences in mean HR, pharmacological responses, and survival of animals with congestive heart failure. Strain-specific differences should be considered in selecting the strains of mice used for transgenic and gene targeting experiments.

Synthesis and crystallographic characterization of [2,2-bis(η5-pentamethylcyclopentadienyl-3,4-bis(trimethylsilyl-2-zirconafuran-5-one-κO5]triisobutylaluminium

Directory of Open Access Journals (Sweden)

Vladimir V. Burlakov

2018-04-01

Full Text Available The crystal structure of the title zwitterionic zirconocene complex containing a furanone unit, [AlZr(C10H152(C4H93(C9H18O2Si2], is reported. On reacting a zirconafuranone with two equivalents of HAl(i-Bu2, disproportionation of the Lewis acid results in the formation of a triisobutylaluminium fragment, Al(i-Bu3, which coordinates to the exocyclic carbonyl O atom of the zirconafuranone ring. Single-crystal X-ray diffraction reveals that the zirconafuranone ring remains intact with coordination of the aluminium to the exocyclic O atom. One of the i-butyl groups is disordered over two sets of sites, with an occupancy ratio of 0.731 (3:0.269 (3.

Silicoaluminates as “Support Activator” Systems in Olefin Polymerization Processes

Science.gov (United States)

Tabernero, Vanessa; Camejo, Claudimar; Terreros, Pilar; Alba, María Dolores; Cuenca, Tomás

2010-01-01

In this work we report the polymerization behaviour of natural clays (montmorillonites, MMT) as activating supports. These materials have been modified by treatment with different aluminium compounds in order to obtain enriched aluminium clays and to modify the global Brönsted/Lewis acidity. As a consequence, the intrinsic structural properties of the starting materials have been changed. These changes were studied and these new materials used for ethylene polymerization using a zirconocene complex as catalyst. All the systems were shown to be active in ethylene polymerization. The catalyst activity and the dependence on acid strength and textural properties have been also studied. The behaviour of an artificial silica (SBA 15) modified with an aluminium compound to obtain a silicoaluminate has been studied, but no ethylene polymerization activity has been found yet.

Proceedings of the Summit on ANSAs: Understanding Strategic Roles and Operational Dynamics

Science.gov (United States)

2010-11-01

23 franchises ”, or what Marc Sagemann (2008) describes as “leaderless jihad”, calls into question whether this still remains a necessary...community at a function some months earlier. As he and one of the community members left the restaurant and arrived at their cars, there was a scratch

A chemical definition of the effective reducing power of thulium(II) diiodide by its reactions with cyclic unsaturated hydrocarbons.

Science.gov (United States)

Fedushkin, I L; Bochkarev, M N; Dechert, S; Schumann, H

2001-08-17

Thulium diiodide reduces cyclic aromatic hydrocarbons that have reduction potentials more positive than - 2.0 V versus SCE. Thus, TmI2 reacts with cyclooctatetraene or acenaphthylene in THF, or with lithium anthracenide in 1,2-dimethoxyethane (DME) to give thulium triiodide and the thulium(III) complexes [(eta8-C8H8)TmI(thf)2] (1), rac-ansa-[(eta5-C12H8)2TmI(thf)] (2), or [(eta2-C14H10)TmI-(dme)2] (3), respectively. The molecular structures of 1-3 were determined by single-crystal X-ray diffraction.

Zirconocene silanolate complexes and their heterogeneous siliceous analogues as catalysts for phenylsilane dehydropolymerization

Czech Academy of Sciences Publication Activity Database

Varga, V.; Horáček, Michal; Bastl, Zdeněk; Merna, J.; Císařová, I.; Sýkora, Jan; Pinkas, Jiří

2012-01-01

Roč. 179, č. 1 (2012), s. 130-139 ISSN 0920-5861 R&D Projects: GA ČR GA203/09/1574; GA AV ČR KAN100400701 Institutional research plan: CEZ:AV0Z40400503; CEZ:AV0Z40720504 Keywords : catalysis * dehydrocoupling * polysilanes Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.980, year: 2012

Development and Experimental Study of Phantoms for Mapping Skin Chromophores

Directory of Open Access Journals (Sweden)

Silapetere A.

2014-06-01

Full Text Available Mūsdienās multispektrālās attēlošanas iekārtas izmanto ādas parametru un fizioloģisko procesu aprakstīšanai gan pētniecības, gan diagnostikas nolūkiem. Iekārtu darbības uzlabošanai ir nepieciešams labāk saprast gaismas mijiedarbību ar audiem, kā arī veikt šo iekārtu kalibrēšanu ar ādas maketu. Redzamā un tuvā infrasarkanā optiskā diapazona spektroskopijā ir svarīgi ādas maketi, kas simulē audu slāņaino struktūru un ķīmiskās īpašības, kā arī maketi, kas ir bioloģiski līdzvērtīgi. Šajā pētījumā tika izveidots ādas makets no bioloģiskām un ķīmiski sintezētām struktūrām. Ādas maketa izveidei tika izmantota fibrīna matrica ar dermālo un epidermālo šūnu piejaukumu, lai imitētu ādas slāņaino struktūru. Fibrīna matrica tiek veidota no 0,47 ml asins plazmas, 0,4 ml fizioloģiskā šķīduma, 0,8 μl treneksāmskābes un 89,4 μl kalcija glukanāta. Izveidoto matricu ievieto šūnu inkubatorā, lai tā polimerizētos. Nākošais slānis tiek veidots ar dermālo šūnu piejaukumu (180-270 šūnas, un pēdējais fibrīna matriksa slānis tiek veidots ar epidermālo šūnu piejaukumu (270 šūnas un šūnu augšanu veicinošu serumu (FBS. Šūnu kultivēšanai nepieciešamas vismaz divas nedēļas. Šajā slāņainajā struktūrā ir iespējams pievienot ādas hromoforu simulējošus iekļāvumus. Optiskajā diapazonā no 450-900 nm ādas hromoforas, kurām ir visizteiktākais spektrs, ir bilirubīns, melanīns un hemoglobīns. Lai simulētu ādas hromoforu spektrālās īpašības, tika izmantots sintezēts bilirubīns, eritrocītu masa un nigrozīns. Lai izpētītu šī maketa iekārtu kalibrēšanas potenciālu, tika izveidoti 76 paraugi, kur katros 24 paraugos bija pievienots viens no absorbentiem ar dažādām koncentrācijām. Pilna ādas maketa audzēšanai nepieciešamas divas nedēļas, lai ātrāk tiktu iegūti pirmie rezultāti tika veidoti maketi bez dermālo un epiderm

SambVca 2. A Web Tool for Analyzing Catalytic Pockets with Topographic Steric Maps

KAUST Repository

Falivene, Laura; Credendino, Raffaele; Poater, Albert; Petta, Andrea; Serra, Luigi; Oliva, Romina; Scarano, Vittorio; Cavallo, Luigi

2016-01-01

Developing more efficient catalysts remains one of the primary targets of organometallic chemists. To accelerate reaching this goal, effective molecular descriptors and visualization tools can represent a remarkable aid. Here, we present a Web application for analyzing the catalytic pocket of metal complexes using topographic steric maps as a general and unbiased descriptor that is suitable for every class of catalysts. To show the broad applicability of our approach, we first compared the steric map of a series of transition metal complexes presenting popular mono-, di-, and tetracoordinated ligands and three classic zirconocenes. This comparative analysis highlighted similarities and differences between totally unrelated ligands. Then, we focused on a recently developed Fe(II) catalyst that is active in the asymmetric transfer hydrogenation of ketones and imines. Finally, we expand the scope of these tools to rationalize the inversion of enantioselectivity in enzymatic catalysis, achieved by point mutation of three amino acids of mononuclear p-hydroxymandelate synthase.

FINAL TECHNICAL REPORT Synthetic, Structural and Mechanistic Investigations of Olefin Polymerization Catalyzed by Early Transition Metal Compounds

Energy Technology Data Exchange (ETDEWEB)

Bercaw, John E. [California Institute of Technology

2014-05-23

The goal of this project is to develop new catalysts and provide understanding of ligand effects on catalyst composition in order to guide development of superior catalyst systems for polymerization of olefins. Our group is designing and synthesizing new “LX2”,“pincer” type ligands and complexing early transition metals to afford precatalysts. In a collaboration with Hans Brintzinger from the University of Konstanz, we are also examining the structures of the components of catalyst systems obtained from reaction of zirconocene dichlorides with aluminum alkyls and aluminum hydrides. Such systems are currently used commercially to produce polyolefins, but the nature of the active and dormant species as well as the mechanisms of their interconversions are not understood. New information on catalyst design and performance may lead to new types of polymers and/or new chemical transformations between hydrocarbons and transition metal centers, ultimately contributing to the development of catalytic reactions for the production of fuels, commodity and polymeric materials.

SambVca 2. A Web Tool for Analyzing Catalytic Pockets with Topographic Steric Maps

KAUST Repository

Falivene, Laura

2016-06-27

Developing more efficient catalysts remains one of the primary targets of organometallic chemists. To accelerate reaching this goal, effective molecular descriptors and visualization tools can represent a remarkable aid. Here, we present a Web application for analyzing the catalytic pocket of metal complexes using topographic steric maps as a general and unbiased descriptor that is suitable for every class of catalysts. To show the broad applicability of our approach, we first compared the steric map of a series of transition metal complexes presenting popular mono-, di-, and tetracoordinated ligands and three classic zirconocenes. This comparative analysis highlighted similarities and differences between totally unrelated ligands. Then, we focused on a recently developed Fe(II) catalyst that is active in the asymmetric transfer hydrogenation of ketones and imines. Finally, we expand the scope of these tools to rationalize the inversion of enantioselectivity in enzymatic catalysis, achieved by point mutation of three amino acids of mononuclear p-hydroxymandelate synthase.

Hydrosilane-B(C6F5)3 adducts as activators in zirconocene catalyzed ethylene polymerization

Czech Academy of Sciences Publication Activity Database

Varga, Vojtěch; Lamač, Martin; Horáček, Michal; Gyepes, Robert; Pinkas, Jiří

2016-01-01

Roč. 45, MAY 2016 (2016), s. 10146-10150 ISSN 1477-9226 R&D Projects: GA ČR(CZ) GAP207/12/2368; GA ČR(CZ) GA14-08531S Institutional support: RVO:61388955 Keywords : ethylene * zirconium compounds * polymerization Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 4.029, year: 2016

MAGNEŢI MOLECULARI – TRECEREA DE LA LIGANZI DE TIP SALEN SPRE TIOSEMICARBAZONE

Directory of Open Access Journals (Sweden)

Mihail SECU

2016-02-01

Full Text Available Au fost scoşi în evidenţă compuşi coordinativi ai manganului(III cu liganzi tip Salen ce posedă proprietăţi de magneţi moleculari (SMM sau lanţuri magnetice (SCM. A fost relatat principiul de asamblare a bis(salicilidenizotiosemi­car­ba­zi­da­ţilor similari liganzilor de tip Salen, pentru identificarea şi descrierea unor noi metode raţionale de sinteză a mole­culelor magnetice şi a lanţurilor magnetice, având în calitate de building block aceşti complecşi de mangan(III. SINGLE MOLECULE MAGNETS– Switching from SALEN type ligands to thiosemicarbazonesThere were highlighted manganese(III coordination compounds with Salen type ligands, which exhibit single molecule magnet (SMM and single chain magnet (SCM behaviour. It was narrated the principle of assembly bis(salicylideneisothio­semicarbazide similar with Salen type ligands, for identify and describe the new methods of rational synthesis of single molecule magnets and single chain magnets, which have as building blocks these manganese(III complexes. 

SECURITATEA REȚELELOR INFORMATICE

Directory of Open Access Journals (Sweden)

Tudor BRAGARU

2018-03-01

Full Text Available În condiţiile utilizării în masă a reţelelor informatice şi desfăşurării diverselor activităţi profesionale mediate de reţele şi dispozitivele mobile conectate, conştientizarea şi contracararea riscurilor devine foarte importantă atât pentru mediul de afaceri, mediul social, cât şi pentru cel personal, privat. Lucrarea prezintă o privire de sinteză asupra cerin­ţelor de securitate, metodelor de atac/ameninţărilor, riscurilo-r, vulnerabilităţilor şi tehnicilor de atenuare şi prevenire a riscurilor informatice preponderent pentru reţele corporative.NETWORKS SECURITYÎn terms of mass use of computer networks and the deployment of various professional activities mediated by networks and connected mobile devices, risk awareness and counseling becomes very important, both for the business environment, the social environment and for the private and private ones. The paper presents a summary of security requirements, attack/threats, risks, vulnerabilities, and mitigation and prevention techniques predominantly for corporate networks.

Kurutun Yapılışı ve Bileşimi Üzerine bir Araştırma

Directory of Open Access Journals (Sweden)

Nurhan Akyüz

2015-02-01

Full Text Available Bu araştırmada Trabzon ve Erzurum piyasasından şansa bağlı olarak alınan 13 adet kurut örneği üzerinde mikrobiyolojik, fiziksel ve kimyasal araştırmalar yapılmıştır. Belirlenen değerler ortalama olarak şöyledir: Toplam mikroorganizma 8.41x103/g, maya ve küf 5.005x103; kurumadde, %79.69, yağ %10.58, yağsız kurumadde %69.12, bütün kül %10.66, protein %52.89, saf kül %1.40, tuz %9.66, kurumaddede tuz %12.60, kurumaddede yağ %13.05, asitlik derecesi 59.75 SH.

The significance of amlodipine on autonomic nervous system adjustment (ANSA method: A new approach in the treatment of hypertension

Directory of Open Access Journals (Sweden)

Milovanović Branislav

2009-01-01

Full Text Available Introduction. Cardiovascular autonomic modulation is altered in patients with essential hypertension. Objective To evaluate acute and long-term effects of amlodipine on cardiovascular autonomic function and haemodynamic status in patients with mild essential hypertension. Methods. Ninety patients (43 male, mean age 52.12 ±10.7 years with mild hypertension were tested before, 30 minutes after the first 5 mg oral dose of amlodipine and three weeks after monotherapy with amlodipine. A comprehensive study protocol was done including finger blood pressure variability (BPV and heart rate variability (HRV beat-to-beat analysis with impedance cardiography, ECG with software short-term HRV and nonlinear analysis, 24-hour Holter ECG monitoring with QT and HRV analysis, 24-hour blood pressure (BP monitoring with systolic and diastolic BPV analysis, cardiovascular autonomic reflex tests, cold pressure test, mental stress test. The patients were also divided into sympathetic and parasympathetic groups, depending on predominance in short time spectral analysis of sympathovagal balance according to low frequency and high frequency values. Results. We confirmed a significant systolic and diastolic BP reduction, and a reduction of pulse pressure during day, night and early morning hours. The reduction of supraventricular and ventricular ectopic beats during the night was also achieved with therapy, but without statistical significance. The increment of sympathetic activity in early phase of amlodipine therapy was without statistical significance and persistence of sympathetic predominance after a few weeks of therapy detected based on the results of short-term spectral HRV analysis. All time domain parameters of long-term HRV analysis were decreased and low frequency amongst spectral parameters. Amlodipne reduced baroreflex sensitivity after three weeks of therapy, but increased it immediately after the administration of the first dose. Conclusion. The results

An efficient absorbing system for spectrophotometric determination of nitrogen dioxide

Science.gov (United States)

Kaveeshwar, Rachana; Amlathe, Sulbha; Gupta, V. K.

A simple and sensitive spectrophotometric method for determination of atmospheric nitrogen dioxide using o-nitroaniline as an efficient absorbing, as well as diazotizing, reagent is described. o-Nitroaniline present in the absorbing medium is diazotized by the absorbed nitrite ion to form diazonium compound. This is later coupled with 1-amino-2-naphthalene sulphonic acid (ANSA) in acidic medium to give red-violet-coloured dye,having λmax = 545 nm. The isoamyl extract of the red azo dye has λmax = 530 nm. The proposed reagents has ≈ 100% collection efficiency and the stoichiometric ratio of NO 2:NO 2- is 0.74. The other important analytical parameters have been investigated. By employing solvent extraction the sensitivity of the reaction was increased and up to 0.03 mg m -3 nitrogen dioxide could be estimated.

Early-transition-metal ketenimine complexes : Synthesis, reactivity, and structure of ketenimine-containing titanocene and zirconocene complexes

NARCIS (Netherlands)

Fandos, R; Lanfranchi, M; Otero, A; Pellinghelli, MA; Ruiz, MJ; Teuben, JH

1997-01-01

Reaction of Cp2M(PMe3)(2) complexes (M = Ti, Zr; Cp = eta(5)-C5H5) with the N-(p-tolyl)-diphenylketenimine Ph'N=C=CPh2 (Ph' = p-MeC6H4) in a 1:1 molar ratio affords the ketenimine-containing metallocene derivatives Cp2M(eta(2)-(C,N)-Ph'N=C=CPh2)(PMe3) (M = Ti (1); Zr (2)). The ketenimine ligand

Steric and electronic effects of 1,3-disubstituted cyclopentadienyl ligands on metallocene derivatives of Cerium, Titanium, Manganese, and Iron

Energy Technology Data Exchange (ETDEWEB)

Sofield, Chadwick Dean [Univ. of California, Berkeley, CA (United States)

2000-05-01

Sterically demanding 1,3-disubstituted cyclopentadienyl ligands were used to modify the physical properties of the corresponding metallocenes. Sterically demanding ligands provided kinetic stabilization for trivalent cerium compounds. Tris(di-t-butylcyclopentadienyl)cerium was prepared and anion competition between halides and cyclopentadienyl groups which had complicated synthesis of the tris(cyclopentadienyl)compound was qualitatively examined. Bis(di-t-butylcyclopentadienyl)cerium methyl was prepared and its rate of decomposition, by ligand redistribution, to tris(di-t-butylcyclopentadienyl)cerium was shown to be slower than the corresponding rate for less sterically demanding ligands. Asymmetrically substituted ligands provided a symmetry label for examination of chemical exchange processes. Tris[trimethylsilyl(t-butyl)cyclopentadienyl]cerium was prepared and the rate of interconversion between the C1 and C3 isomers was examined. The enthalpy difference between the two distereomers is 7.0 kJ/mol. The sterically demanding cyclopentadienyl ligands ansa-di-t-butylcyclopentadiene (Me₂Si[(Me₃C)₂C₅H₃]₂), ansa-bis(trimethylsilyl)cyclopentadiene (Me₂Si[(Me₃Si)₂C₅H₃]₂) and tetra-t-butylfulvalene and metallocene derivatives of the ligands were prepared and their structures were examined by single crystal X-ray crystallography. The effect that substituents on the cyclopentadienyl ring have on the pi-electron system of the ligand was examined through interaction between ligand and metal orbitals. A series of 1,3-disubstituted manganocenes was prepared and their electronic states were determined by solid-state magnetic susceptibility, electron paramagnetic resonance, X-ray crystallography, and variable temperature UV-vis spectroscopy. Spin-equilibria in [(Me₃C)₂C₅H₃]₂Mn and [(Me₃

Effects of supported (nBuCp)2ZrCl2 catalyst active center multiplicity on crystallization kinetics of ethylene homo- and copolymers

KAUST Repository

Atiqullah, Muhammad

2014-07-01

Two different supported zirconocene, that is, bis(n-butylcyclopentadienyl) zirconium dichloride (nBuCp)2ZrCl2, catalysts were synthesized. Each catalyst was used to prepare one ethylene homopolymer and one ethylene-1-hexene copolymer. Catalyst active center multiplicity and polymer crystallization kinetics were modeled. Five separate active center types were predicted, which matched the successive self-nucleation and annealing (SSA) peak temperatures. The predicted crystallinity well matched the differential scanning calorimetric (DSC) values for a single Avrami-Erofeev index, which ranged between 2 and 3 for the polymers experimented. The estimated apparent crystallization activation energy Ea did not vary with cooling rates, relative crystallinity α, and crystallization time or temperature. Therefore, the concept of variable/instantaneous activation energy was not found to hold. Ea linearly increased with the weight average lamellar thickness Lwav DSC-GT; and for each homopolymer, it exceeded that of the corresponding copolymer. Higher Ea, hence slower crystallization, was identified as a pre-requisite to attain higher crystallinity. Crystallization parameters were correlated to polymer backbone parameters, which are influenced by catalyst active center multiplicity. © 2013 Taiwan Institute of Chemical Engineers.

Radiation Synthesis of Stannous Dibromodibutyl; Synthese radiochimique de l'etain dibromopibutyle; Radiatsionno-khimicheskij sintez dibromdibutilolova; Sintesis radioquimica del dffiromodibutilestano

Energy Technology Data Exchange (ETDEWEB)

Abramova, L. V.; Vereshchinskij, I. V.; Kocheshkov, K. A.; Miretskij, V. Yu.; Pozdneev, V. V.; Ryabukhin, Yu. S.; Sheverdina, N. I.

1963-11-15

It was first established in 1958 by Abramova, Koeheshkov and Sheverdina that stannous organic compounds could in principle be synthesized by the action of Co{sup 60} gamma irradiation on mixtures of stannous metal and the corresponding alkyl halides. Under the conditions in which the experiments were carried out, in glass equipment without mixing, it was not possible to clarify the kinetic formation-mechanism of this type of organo-metallic compound. The present experiment was carried out in order to discover the effects of a number of factors on the irradiation synthesis velocity of stannous organic compounds in a stannous dibromodibutyl sample. For this purpose a special device with periodic loading of the components and unloading of the reaction products was designed and manufactured. Its excellent features included thermo-setting, effective mixing, and the periodical selection of test-samples for analysis. The main loop - a 2-1 stainless-steel reaction vessel - was provided with a mixer. The device was mounted on a Co{sup 60} gamma irradiation source. Experiments were carried out at a temperature of 80 {+-} 5''S and at atmospheric pressure. The dose intensity amounted to {approx} 50 rad/s (ferrous sulphate dosimeter). Powdered stannous metal and butyl bromide, differing in degree of purity, were employed. The reactivity components were applied in different ratios. It was established that under these conditions a controlled radiation-chemistry reaction takes place, the main result of which is a high yield of stannous dibromodibutyl. It was shown that the process has an induction period whose duration depends upon the purity of the initial butyl bromide; this has a notable effect on the formation velocity of the end product. It was found that the tin, not used up in the reaction, can be repeatedly used for the purpose of obtaining stannous dibromodibutyl and the induction period entirely eliminated. The features described provide the pre- requisites for an uninterrupted process. A reaction mechanism is proposed to explain the principles of the process which give a substantial irradiation yield. (author) [French] Le fait qu'il est, en principe, possible de realiser la synthese de composes organiques de l'etain en soumettant un melange d'etain metallique et d'halogenures appropries a l'action des rayons gamma du {sup 60}Co a ete etabli pour la premiere fois par Abramova, Kotchechkov et Cheverdina en 1958. Les conditions des experiences, qui etaient executees a l'aide d'un appareillage en vene depourvu de melangeur, ne permettait pas de determiner les lois cinetiques qui president a la formation des composes organometalliques de cette categorie. L'etude consideree a ete entreprise pour elucider l'influence qu'exercent plusieurs facteurs sur la vitesse a laquelle se produit la synthese radiochimique des composes organiques de l'etain, en prenant comme exemple l'etain dibromodibutyle. A cette fin, les auteurs ont concu et construit une installation speciale assurant le chargement periodique des composants et l'evacuation des produits de la reaction. Cette installation permettait de maintenir une temperature constante, d'assurer une agitation efficace et de prelever periodiquement des echantillons aux fins d'analyse. Son element essentiel - un recipient en acier inoxydable d'une contenance de deux litres ou se produisait la reaction - etait equipe d'un melangeur. Elle comprenait une source de rayons y{gamma} au {sup 60}Co. Les experiences ont eu lieu a une temperature de 80 {+-} 5{sup o}C, sous pression atmospherique. Le debit de dose, mesure a l'aide d'un dosimetre au sulfate ferreux, etait d'environ 50 rad/s. On a utilise de la poudre d'etain metallique et du bromure de butyle de puretes differentes. Les substances entrant dans la reaction ont ete employees en proportions diverses. On a constate qu'il se produisait, dans ces conditions, une reaction radiochimique orientee au cours de laquelle se formait essentiellement de l'etain dibromodibutyle en grande quantite. Les auteurs montrent que le processus comporte une periode d'amorcage dont la duree depend du degre de purete du bromure de butyle initial. Ce facteur exerce en outre une influence sensible sur la vitesse, de formation du produit final. On a constate que l'etain qui n'est pas entre dans la reaction peut etre utilise de nouveau pour la production d'etain dibromodibutyle, mais que dans ce cas la periode d'amorcage est totalement inexistante. Les particularites mentionnees creent les conditions necessaires pour la realisation d'un processus continu. Les auteurs proposent un mecanisme reactionnel pour expliquer la regularite du processus dont le rendement radiochimique est eleve. (author) [Spanish] La posibilidad de efectuar la sintesis de compuestos organicos del estafio por irradiacion con los rayos gamma del {sup 60}Co de mezclas de estano y de los respectivos haluros alquilicos fue establecida por primera vez en 1958 por Abramova, Kocheshkovy Sheverdina. Las condiciones en que se realizaron los experimentos, en aparatos de vidrio, sin agitadores, no permitieron determinar las leyes cineticas de la formacion de ese tipo de compuestos organo-metalicos. El presente trabajo sirvio para aclarar la influencia de una serie de factores sobre la velocidad de la sintesis radioquimica de los compuestos organicos del estafio tomando como ejemplo el dibromodibutilestaflo. Con ese objeto, se construyo un aparato especial que facilita la carga periodica de los reactivos y la descarga de los productos de reaccion. Dicho aparato permite estabilizar la temperatura, agitar eficazmente los reactivos y extraer periodicamente muestras para analisis. El elemento esencial es el recipiente de reaccion, de acero inoxidable, de 2-1 de capacidad, provisto de un agitador. El aparato se coloca sobre una fuente gamma de {sup 60}Co. Los experimentos se efectuaron a temperaturas de 80 {+-}5{sup o}C y a presion atmosferica. La intensidad de dosis medida con ayuda de un dosimetro de sulfato de hierro es de {approx}50 rad/s. Se utilizaron diversas proporciones de estafio metalico en polvo y bromuro de butilo de distintos grados de pureza. Se comprobo que en tales condiciones se desarrolla una reaccion radioquimica orientada en virtud de la cual se produce basicamente dibromodibutilestaflo con elevado rendimiento. Se demostro que el proceso tiene un periodo de induccion cuya duracion depende de la pureza del bromuro de butilo inicial. Este mismo factor influye tambien notablemente en la velocidad de formacion del producto final. Se comprobo que el estafio que no interviene en la reaccion puede volver a utilizarse para obtener dibromodibutilestaflo, pero en ese caso se anula por completo el periodo de induccion. Estas propiedades satisfacen los requisitos para la realizacion de un proceso continuo. Los autores proponen un mecanismo de reaccion, para explicar las leyes de este proceso que se desarrolla con un elevado rendimiento radioquimico. (author) [Russian] Printsipial'naya vozmozhnost' sinteza olovoorganicheskikh soedinenij pri dejstvii {gamma}-izlucheniya Co{sup 60} na smesi metallicheskogo olova i sootvetstvuyushchikh galoidalkilov vpervye byla ustanovlena Abramovoj, Kocheshkovym i SHeverdinoj v 1956 g. Usloviya provedeniya opytov v steklyannoj apparature bez peremeshivaniya ne pozvolyali vyyavit' kineticheskie zakonomernosti obrazovaniya ehtogo klassa metalloorganicheskikh soedinenij. Nastoyashchaya rabota byla postavlena dlya vyyasneniya vliyaniya ryada faktorov na skorost' radiatsionno-khimicheskogo sinteza olovoorganicheskikh soedinenij na primere dibromdibutilolova. S ehtoj tsel'yu byla skonstruirovana i izgotovlena spetsial'naya ustanovka s periodicheskoj zagruzkoj komponentov i vygruzkoj produktov reaktsii. Otlichitel'nymi osobennostyami ustanovki yavlyalis' vozmozhnost' ee termostatirovaniya, osushchestvlenie ehffektivnogo peremeshivaniya i periodicheskogo otbora prob dlya analizov. Osnovnoj uzel ustanovki (reaktsionnyj sosud iz nerzhaveyushchej stali ob''emom 2-1) byl snabzhen meshalkoj. Ustanovka montirovalas' na istochnike {gamma}-izlucheniya Co{sup 60}. Opyty provodilis' pri temperature 80 {+-} 5{sup o}C i atmosfernom davlenii. Moshchnost' dozy sostavlyala {approx}50 rad/sek (po ferrosul'fatnomu dozimetru). Primenyalos' metallicheskoe poroshkoobraznoe olovo i bromistyj butil raznoj stepeni ochistki. Komponenty reaktsii bralis' v razlichnykh sootnosheniyakh. Ustanovlennoe chto v dannykh usloviyakh protekaet napravlennaya radiatsionnokhimicheskaya reaktsiya, v rezul'tate kotoroj v osnovnom obrazuetsya dibromdibutilolovo s vysokim kolichestvennym vykhodom. Pokazano, chto protsess protekaet s induktsionnym periodom, dlitel'nost' kotorogo zavisit ot chistoty iskhodnogo bromistogo butila. EHtot zhe faktor zametno vliyaet ne skorost' obrazovaniya tselevogo produkta. Najdeno, chto olovo, ne voshedshee v reaktsiyu, mozhet povtorno ispol'zovat'sya dlya polucheniya dibromdibutilolova. Pri ehtom polnost'yu ustranyaetsya induktsionnyj period. Otmechennye osobennosti sozdayut predposylki dlya provedeniya nepreryvnogo protsessa. Predlozhen mekhanizm reaktsij dlya ob{sup y}asneniya zakonomernostej protsessa, protekayushchego so znachitel'nym radiatsionno-khimicheskim vykhodom. (author)

Study of the anticancer properties of methyl- and phenyl-substituted carbon- and silicon-bridged ansa-titanocene complexes

Czech Academy of Sciences Publication Activity Database

Mijatović, S.; Bulatović, M.; Mojić, M.; Stošić-Grujičić, S.; Miljković, D.; Maksimović-Ivanić, D.; Gómez-Ruiz, S.; Pinkas, Jiří; Horáček, Michal; Kaluderović, G. N.

2014-01-01

Roč. 751, FEB 2014 (2014), s. 361-367 ISSN 0022-328X R&D Projects: GA ČR(CZ) GAP207/12/2368 Institutional support: RVO:61388955 Keywords : titanocene derivatives * cytotoxicity * primary cells Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.173, year: 2014

Development and characterization of radioimmunoassay methods for the measurement of iodothyronines (T4, T3 and rT3)

International Nuclear Information System (INIS)

Russo, E.M.K.; Vieira, J.G.H.; Barros Maciel, R.M. de; Fonseca, R.M.G.

1982-01-01

The experience acquired in the development of radioimmunoassay for T 4 , T 3 and rT 3 in unextrated serum is described. Antisera were produced in rabbits using iodothyronines conjugated to bovine serum albumin: the antisera selected provided the development of sensitive and specific radioassay methods. Stable high activity T 3 , T 4 and rT 3 tracers were prepared by iodination of 3,5 T 2 , T 3 and 3,3' T 2 by the chloramine-T method, and purified by column chromatography on Sephadex G25. Binding of those iodothyronines to endogenous serum proteins was blocked by including 8-aniline-1-naphtalene sulphonic acid (ANSA) in the T 4 and T 3 assays and thymerosal in the rT 3 assay. Normal values were defined in 46 healthy euthyroid adults of both sexes: T 4 = 7,1 +- 1,3μg/dl; T 3 = 139 +- 35ng/dl and rT 3 = 18,0 +- 7,9ng/dl. (Author) [pt

Murder followed by suicide: filicide-suicide mothers in Italy from 1992 to 2010.

Science.gov (United States)

D'Argenio, Alberto; Catania, Giorgia; Marchetti, Marco

2013-03-01

The international literature shows that in 40-50% of the cases, homicides-suicides involving children under the age of 10 are committed by mothers. Here, we report some results on homicides-suicides, in the mother-child relationship, occurred in Italy between 1992 and 2010. We examined 36 cases of filicide-suicide mothers by consulting the archives of RAI, daily newspapers, and the ANSA news agency. We focused on: mothers and children's age, place of residence, date and place of the murder, number and sex of the murdered children, and modality of the homicide-suicide. At the time of the homicide-suicide, the average age of mothers was 35.4. The number of children killed by each mother was one, except in seven cases. All the women had underestimated psychopathological disorders and only six women were regularly treated. The dynamics and characteristics of the events were much more similar to suicides than homicides, so we can consider them as "extensive suicides." © 2013 American Academy of Forensic Sciences.

Aminobenzoates as building blocks for natural product assembly lines.

Science.gov (United States)

Walsh, Christopher T; Haynes, Stuart W; Ames, Brian D

2012-01-01

The ortho-, meta-, and para- regioisomers of aminobenzoate are building blocks for a wide range of microbial natural products. Both the ortho-isomer (anthranilate) and PABA derive from the central shikimate pathway metabolite chorismate while the meta-isomer is not available by that route and starts from UDP-3-aminoglucose. PABA is largely funnelled into folate biosynthesis while anthranilate is the scaffold for biosynthetic elaboration into many natural heterocycles, most notably with its role in indole formation for tryptophan biosynthesis. Anthranilate is also converted to benzodiazepinones, fumiquinazolines, quinoxalines, phenoxazines, benzoxazolinates, quinolones, and phenazines, often with redox enzyme participation. The 5-hydroxy form of 3-aminobenzaote is the starter unit for ansa-bridged rifamycins, ansamitocins, and geldanamycins, whereas regioisomers 2-hydroxy, 4-hydroxy and 2,4-dihydroxy-3-aminobenzoate are key components of antimycin, grixazone, and platencin and platensimycin biosynthesis, respectively. The enzymatic mechanisms for generation of the aminobenzoate regioisomers and their subsequent utilization for diverse heterocycle and macrocycle construction are examined.

Synthesis and structure of ketene complexes of permethylzirconocene and their hydrogenation to zirconium hydrides

Energy Technology Data Exchange (ETDEWEB)

Moore, E.J.; Straus, D.A.; Armantrout, J.; Santarsiero, B.D.; Grubbs, R.H.; Bercaw, J.E.

1983-04-06

The reduction of carbon monoxide by Cp*/sub 2/ZrH/sub 2/ (1, Cp* = n/sup 5/-C/sub 5/Me/sub 5/) is complex and yields a variety of products depending on reaction conditions. Whereas the mechanism leading to trans-(Cp*/sub 2/ZrH)/sub 2/(..mu..-OCH=CHO) from 1 and free CO is relatively well established, the steps leading to cis-(Cp*/sub 2/ZrH)/sub 2/(..mu..-OCH=CHO) (4) from 1, Cp*/sub 2/Zr(CO)/sub 2/ (2), and H/sub 2/ are largely speculative. The favored scheme involves initial attack of 1 at a carbonyl ligand of 2 followed by carbene-carbonyl coupling affording coordinated ''zirconoxy'' ketene 3, which undergoes hydrogenation to 4. The cis geometry of this enediolate product was proposed to result from (i) the structure of 3 in which the bulky Cp*/sub 2/ZrO moieties are sterically constrained in a cis arrangement and (ii) its stereospecific hydrogenation to 4. Recently a general route to titanocene and zirconocene ketene complexes, dehydrohalogenation of haloacyl compounds, has been developed. Application of this methodology to the permethylzirconocene system has led to isolation of monomeric, Lewis base adducts of Cp*/sub 2/Zr(C,O-n/sup 2/-R/sub 2/C=CO). Here the results of a structure determination for Cp*/sub 2/Zr(py)(C,O-n/sup 2/-H/sub 2/C=CO) (py = pyridine) and the stereochemistry of the hydrogenation of the tert-butyl ketene complex, which bears on the proposed CO reduction mechanism are reported.

Importância da anatomia da circulação coronária atrial na operação de Cox para controle da fibrilação atrial The importance of atrial coronary circulation on Cox surgery for control atrial fibrillation

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Marcelo B. JATENE

1999-01-01

Full Text Available Com o advento de novas técnicas cirúrgicas para o tratamento das arritmias cardíacas, em especial da fibrilação atrial, como a cirurgia de Cox, o conhecimento das características e do trajeto das artérias coronárias atriais assumiu grande importância. O objetivo deste trabalho é o estudo desta circulação e a definição dos padrões de irrigação atrial. Para tanto, utilizamos 30 corações a fresco de indivíduos sem cardiopatia prévia, cujas artérias coronárias e ramos foram visibilizados através de injeção de resina vinílica corada com tinta laca preta, seguida de cuidadosa dissecção. Após avaliação macroscópica das peças, não foram encontrados padrões de irrigação uniforme dos átrios. Porém, a artéria do nó sinoatrial (ANSA, quando analisada isoladamente, revelou não apenas padrões de origem, como também padrões de trajeto. Foram descritos 7 padrões de origem e trajeto da ANSA, considerando-se pontos de referências da estrutura anatômica dos átrios. Os padrões descritos, diferente dos encontrados por outros autores, são de fácil interpretação e de aplicabilidade direta em técnicas cirúrgicas que abordam os átrios.Since the appearance of new surgical techniques such as Cox surgery employed for the treatment of cardiac arrhythmia, especially for atrial fibrillation, the knowledge of coronary artery characteristics and courses has been of increasing importance. The aim of this study was the analysis of this circulation and definition of atrial irrigation patterns. Hence, the coronary arteries of 30 normal human hearts were injected with colored resin and carefully dissected. After macroscopic evaluation of the hearts, no atrial irrigation patterns were found. However, when only the sinus atrial node was analyzed, it showed origin patterns as well as course patterns. Seven origin and route patterns of this artery are described, considering the anatomical structure of the atria as reference

Synergistic nonuniform shortening of atrial refractory period induced by autonomic stimulation.

Science.gov (United States)

Takei, M; Furukawa, Y; Narita, M; Ren, L M; Karasawa, Y; Murakami, M; Chiba, S

1991-12-01

We investigated the nonuniform effects of autonomic nerve stimulation of the effective refractory period (ERP) of the right atrium in the anesthetized dog. Stimulation of the discrete intracardiac sympathetic nerves to the sinoatrial (SA) nodal region uniformly shortened ERPs at three sites in the right atrium after administration of atropine. Right ansa subclavia (RS) stimulation similarly shortened ERPs in the absence of atropine. Stimulation of the discrete intracardiac parasympathetic nerves to the SA nodal region (SAP stimulation) shortened ERPs of the right atrium in a nonuniform manner. Simultaneous RS and SAP stimulation additively shortened ERPs at each site and decreased sinus rate much more than SAP stimulation alone. Shortening of ERP induced by SAP stimulation was greater than that induced by RS stimulation at similar absolute changes in heart rate. These results suggest that simultaneous activation of sympathetic and parasympathetic nerves nonuniformly shortens the ERP in the right atrium as the algebraic sum of the individual responses to each stimulation. However, parasympathetics exert the principal neural control over atrial ERP.

Probabilistic vs. deterministic fiber tracking and the influence of different seed regions to delineate cerebellar-thalamic fibers in deep brain stimulation.

Science.gov (United States)

Schlaier, Juergen R; Beer, Anton L; Faltermeier, Rupert; Fellner, Claudia; Steib, Kathrin; Lange, Max; Greenlee, Mark W; Brawanski, Alexander T; Anthofer, Judith M

2017-06-01

This study compared tractography approaches for identifying cerebellar-thalamic fiber bundles relevant to planning target sites for deep brain stimulation (DBS). In particular, probabilistic and deterministic tracking of the dentate-rubro-thalamic tract (DRTT) and differences between the spatial courses of the DRTT and the cerebello-thalamo-cortical (CTC) tract were compared. Six patients with movement disorders were examined by magnetic resonance imaging (MRI), including two sets of diffusion-weighted images (12 and 64 directions). Probabilistic and deterministic tractography was applied on each diffusion-weighted dataset to delineate the DRTT. Results were compared with regard to their sensitivity in revealing the DRTT and additional fiber tracts and processing time. Two sets of regions-of-interests (ROIs) guided deterministic tractography of the DRTT or the CTC, respectively. Tract distances to an atlas-based reference target were compared. Probabilistic fiber tracking with 64 orientations detected the DRTT in all twelve hemispheres. Deterministic tracking detected the DRTT in nine (12 directions) and in only two (64 directions) hemispheres. Probabilistic tracking was more sensitive in detecting additional fibers (e.g. ansa lenticularis and medial forebrain bundle) than deterministic tracking. Probabilistic tracking lasted substantially longer than deterministic. Deterministic tracking was more sensitive in detecting the CTC than the DRTT. CTC tracts were located adjacent but consistently more posterior to DRTT tracts. These results suggest that probabilistic tracking is more sensitive and robust in detecting the DRTT but harder to implement than deterministic approaches. Although sensitivity of deterministic tracking is higher for the CTC than the DRTT, targets for DBS based on these tracts likely differ. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Origem das artérias dos nós sinoatrial e atrioventricular em população do sul da Índia: um estudo angiográfico Origen de las arterias de los nódulos sinusal y atrioventricular en población del Sur de la India: un estudio angiográfico Origin of the sinoatrial and atrioventricular nodal arteries in South Indians: an angiographic study

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Lakshmi Ramanathan

2009-05-01

Full Text Available FUNDAMENTO: Estudar o suprimento arterial do sistema condutor e sua correlação com a dominância das artérias coronárias em população do sul da Índia. OBJETIVO: Determinar angiograficamente as origens da artéria do nó sinoatrial (AnSA e artéria do nó atrioventricular (AnAV em indianos. MÉTODOS: O ESTudo incluiu 300 pacientes consecutivos (114 do sexo feminino e 186 do sexo masculino; idade média, 55 anos, habitantes da região costeira ao sul da Índia, submetidos a cineangiocoronariografia devido a sintomas como dor no peito, angina pectoris ou teste ergométrico positivo. As angiografias incluíram ambas as artérias coronárias (direita e esquerda em posição oblíqua anterior direita e esquerda. A origem da AnSA e AnAV a partir das artérias coronárias foi observada e correlacionada à dominância arterial. RESULTADOS: O nó SA (sinoatrial recebeu suprimento pela artéria coronária direita (ACD em 53% dos casos, pelo ramo circunflexo (Cx da artéria coronária esquerda (ACE em 42,66% dos casos, e em 4,33% dos casos esse nó foi irrigado por ambas as artérias coronárias. O nó AV (atrioventricular também recebeu suprimento sanguíneo com mais frequência da ACD (72,33% dos casos do que do ramo Cx da ACE (27,66%. Surpreendentemente, em nenhum caso este nó recebeu suprimento de ambas as artérias coronárias. CONCLUSÃO: Os Resultados do presente estudo podem auxiliar os cirurgiões cardíacos, sobretudo em cirurgias relacionadas a valvopatias, devido à franca proximidade entre os ramos nodais e o complexo valvar.FUNDAMENTO: Estudiar el suministro arterial del sistema conductor y su correlación con la dominancia de las arterias coronarias en población del Sur de la India. OBJETIVO: Determinar angiográficamente los orígenes de la arteria del nódulo sinusal (AnSA y la arteria del nódulo atrioventricular (AnAV en indios. MÉTODOS: El estudio incluyó 300 pacientes consecutivos (114 del sexo femenino y 186 del sexo

Influence of radiant heating treatments on fusion of high-temperature superconducting yttrium ceramics; Vliyanie termoradiatsionnykh obrabotok na sintez vysokotempiraturnykh sverkhprovodyaschikh ittrievykh keramik

Energy Technology Data Exchange (ETDEWEB)

Bitenbaev, M I; Polyakov, A I [Inst. Yadernoj Fiziki Natsionalnogo Yadernogo Tsentra Respubliki Kazakhstan, Almaty (Kazakhstan)

1999-07-01

Regardless of the fact that the materials made of HTSC-ceramics are promising, there is no any information about their successful practical application in publications. To our opinion, it is explained by the fact, first of all, that the conservative technologies of the powder metallurgy do not allow producing HTSC systems with excellent operating performance (structure homogeneity, long-term stability of Sc properties and etc.). This report presents outcomes of experiments on fusion of yttrium ceramics containing raw components irradiated by g-rays {sup 60}Co under the temperature exceeding 500 degrees C. HTSC properties of ceramics were studied according to their differential spectra of radio-frequency (RF) field absorption. The RF absorption spectrum of yttrium ceramics samples produced according to conservative technology is sufficiently permitted triplet with the Sc transition temperatures range of 80 K, 90 K, 95 K. Irradiation under the increased temperatures and mechanical limitation allow producing samples of yttrium HTSC-ceramics with sufficient homogeneous structure and superconducting properties that are stable to air conditions for not less than one year.

DIRECT IMAGING AND SPECTROSCOPY OF A YOUNG EXTRASOLAR KUIPER BELT IN THE NEAREST OB ASSOCIATION

International Nuclear Information System (INIS)

Currie, Thayne; Lisse, Carey M.; Kuchner, Marc; Madhusudhan, Nikku; Kenyon, Scott J.; Thalmann, Christian; Carson, Joseph; Debes, John

2015-01-01

We describe the discovery of a bright, young Kuiper belt–like debris disk around HD 115600, a ∼1.4–1.5 M ⊙ , ∼15 Myr old member of the Sco–Cen OB Association. Our H-band coronagraphy/integral field spectroscopy from the Gemini Planet Imager shows the ring has a (luminosity-scaled) semimajor axis of (∼22 AU) ∼ 48 AU, similar to the current Kuiper belt. The disk appears to have neutral-scattering dust, is eccentric (e ∼ 0.1–0.2), and could be sculpted by analogs to the outer solar system planets. Spectroscopy of the disk ansae reveal a slightly blue to gray disk color, consistent with major Kuiper belt chemical constituents, where water ice is a very plausible dominant constituent. Besides being the first object discovered with the next generation of extreme adaptive optics systems (i.e., SCExAO, GPI, SPHERE), HD 115600's debris ring and planetary system provide a key reference point for the early evolution of the solar system, the structure, and composition of the Kuiper belt and the interaction between debris disks and planets

DIRECT IMAGING AND SPECTROSCOPY OF A YOUNG EXTRASOLAR KUIPER BELT IN THE NEAREST OB ASSOCIATION

Energy Technology Data Exchange (ETDEWEB)

Currie, Thayne [National Astronomical Observatory of Japan, Subaru Telescope, Hilo, HI (United States); Lisse, Carey M. [Applied Physics Laboratory, The Johns Hopkins University, Laurel, MD (United States); Kuchner, Marc [NASA Goddard Space Flight Center, Greenbelt, MD (United States); Madhusudhan, Nikku [Institute for Astronomy, University of Cambridge, Cambridge (United Kingdom); Kenyon, Scott J. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States); Thalmann, Christian [ETH-Zurich, Zurich (Switzerland); Carson, Joseph [Department of Physics and Astronomy, The College of Charleston, Charleston, SC (United States); Debes, John [Space Telescope Science Institute, Baltimore, MD (United States)

2015-07-01

We describe the discovery of a bright, young Kuiper belt–like debris disk around HD 115600, a ∼1.4–1.5 M{sub ⊙}, ∼15 Myr old member of the Sco–Cen OB Association. Our H-band coronagraphy/integral field spectroscopy from the Gemini Planet Imager shows the ring has a (luminosity-scaled) semimajor axis of (∼22 AU) ∼ 48 AU, similar to the current Kuiper belt. The disk appears to have neutral-scattering dust, is eccentric (e ∼ 0.1–0.2), and could be sculpted by analogs to the outer solar system planets. Spectroscopy of the disk ansae reveal a slightly blue to gray disk color, consistent with major Kuiper belt chemical constituents, where water ice is a very plausible dominant constituent. Besides being the first object discovered with the next generation of extreme adaptive optics systems (i.e., SCExAO, GPI, SPHERE), HD 115600's debris ring and planetary system provide a key reference point for the early evolution of the solar system, the structure, and composition of the Kuiper belt and the interaction between debris disks and planets.

ORGANOPROTECTIVE EFFECTS OF THE FIXED COMBINATION OF ANGIOTENSIN-CONVERTING ENZYME INHIBITOR LISINOPRIL AND DIURETIC HYDROCHLOROTHIAZIDE

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E. A. Ryabikhin

2016-01-01

Full Text Available Aim. To compare the antihypertensive and metabolic effects of combined therapy (carvedilol reception and «School of the hypertensive patient» with these of the carvedilol monotherapy in young patients with arterial hypertension (HT of 1-2 degrees with overweight and obesity.Material and methods. 63 out-patients with HT of 1-2 degrees (aged 18-27 y.o. with overweight and obesity were included in the open parallel randomized clinical preventive trail. Patients wеre randomized into 2 groups. All hypertensive patients received the carvedilol (Vedicardol, Sintez, Russia 25 mg daily. Carvedilol dose was enlarged twice in case of insufficient antihypertensive effect. Patients of the main group (n=32 also passed through the special educational program «School for hypertensive patients». Changes in blood pressure (BP level, body mass index, biochemical markers and risk factors were evaluated initially and in 24 weeks of therapy.Results. Patients of the main group had more significant risk factor manifestations decrease than in group of comparison. More significant body mass index decrease was also observed in the main group in comparison with group of comparison: from 32,5±0,4 to 26,4±0,7 kg/m2 (p<0,01 and from 31,8±0,8 to 28,9±1,18 kg/m2 (p<0,05, respectively. In patients of the main group systolic and diastolic BP decreased by 20,1% and 25,6%, respectively, wile in patients of the group of comparison – by 18,9% and 26%, respectively.Conclusion. It is reasonable to combine carvedilol therapy with special training in the young hypertensive patients with overweight and obesity.

ORGANOPROTECTIVE EFFECTS OF THE FIXED COMBINATION OF ANGIOTENSIN-CONVERTING ENZYME INHIBITOR LISINOPRIL AND DIURETIC HYDROCHLOROTHIAZIDE

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E. A. Ryabikhin

2009-01-01

Full Text Available Aim. To compare the antihypertensive and metabolic effects of combined therapy (carvedilol reception and «School of the hypertensive patient» with these of the carvedilol monotherapy in young patients with arterial hypertension (HT of 1-2 degrees with overweight and obesity.Material and methods. 63 out-patients with HT of 1-2 degrees (aged 18-27 y.o. with overweight and obesity were included in the open parallel randomized clinical preventive trail. Patients wеre randomized into 2 groups. All hypertensive patients received the carvedilol (Vedicardol, Sintez, Russia 25 mg daily. Carvedilol dose was enlarged twice in case of insufficient antihypertensive effect. Patients of the main group (n=32 also passed through the special educational program «School for hypertensive patients». Changes in blood pressure (BP level, body mass index, biochemical markers and risk factors were evaluated initially and in 24 weeks of therapy.Results. Patients of the main group had more significant risk factor manifestations decrease than in group of comparison. More significant body mass index decrease was also observed in the main group in comparison with group of comparison: from 32,5±0,4 to 26,4±0,7 kg/m2 (p<0,01 and from 31,8±0,8 to 28,9±1,18 kg/m2 (p<0,05, respectively. In patients of the main group systolic and diastolic BP decreased by 20,1% and 25,6%, respectively, wile in patients of the group of comparison – by 18,9% and 26%, respectively.Conclusion. It is reasonable to combine carvedilol therapy with special training in the young hypertensive patients with overweight and obesity.

Monochloro non-bridged half-metallocene-type zirconium complexes containing phosphine oxide-(thio)phenolate chelating ligands as efficient ethylene polymerization catalysts.

Science.gov (United States)

Tang, Xiao-Yan; Wang, Yong-Xia; Liu, San-Rong; Liu, Jing-Yu; Li, Yue-Sheng

2013-01-14

A series of novel monochloro half-zirconocene complexes containing phosphine oxide-(thio)phenolate chelating ligands of the type, ClCp'Zr[X-2-R(1)-4-R(2)-6-(Ph(2)P=O)C(6)H(2)](2) (Cp' = C(5)H(5), 2a: X = O, R(1) = Ph, R(2) = H; 2b: X = O, R(1) = F, R(2) = H; 2c: X = O, R(1) = (t)Bu, R(2) = H; 2d: X = O, R(1) = R(2) = (t)Bu; 2e: X = O, R(1) = SiMe(3), R(2) = H; 2f: X = S, R(1) = SiMe(3), R(2) = H; Cp' = C(5)Me(5), 2g: X = O, R(1) = SiMe(3), R(2) = H), have been synthesized in high yields. These complexes were identified by (1)H {(13)C} NMR and elemental analyses. Structures for 2b, 2c and 2f were further confirmed by X-ray crystallography. Structural characterization of these complexes reveals crowded environments around the zirconium. Complexes 2b and 2c adopt six-coordinate, distorted octahedral geometry around the zirconium center, in which the equatorial positions are occupied by three oxygen atoms of two chelating phosphine oxide-bridged phenolate ligands and a chlorine atom. The cyclopentadienyl ring and one oxygen atom of the ligand are coordinated on the axial position. Complex 2f also folds a six-coordinate, distorted octahedral geometry around the Zr center, consisting of a Cp-Zr-O (in P=O) axis [177.16°] and a distorted plane of two sulfur atoms and one oxygen atom of two chelating phosphine oxide-bridged thiophenolate ligands as well as a chlorine atom. When activated by modified methylaluminoxane (MMAO), all the complexes exhibited high activities towards ethylene polymerization at high temperature (75 °C), giving high molecular weight polymers with unimodal molecular weight distribution. The formation of 14-electron, cationic metal alkyl species might come from the Zr-O (in phenol ring) bond cleavage based on the DFT calculations study.

Structure-activity relationship of the ionic cocrystal: 5-amino-2-naphthalene sulfonate·ammonium ions for pharmaceutical applications

Science.gov (United States)

Sangeetha, M.; Mathammal, R.

2018-02-01

The ionic cocrystals of 5-amino-2-naphthalene sulfonate · ammonium ions (ANSA-ṡNH4+) were grown under slow evaporation method and examined in detail for pharmaceutical applications. The crystal structure and intermolecular interactions were studied from the single X-ray diffraction analysis and the Hirshfeld surfaces. The 2D fingerprint plots displayed the inter-contacts possible in the ionic crystal. Computational DFT method was established to determine the structural, physical and chemical properties. The molecular geometries obtained from the X-ray studies were compared with the optimized geometrical parameters calculated using DFT/6-31 + G(d,p) method. The band gap energy calculated from the UV-Visible spectral analysis and the HOMO-LUMO energy gap are compared. The theoretical UV-Visible calculations helped in determining the type of electronic transition taking place in the title molecule. The maximum absorption bands and transitions involved in the molecule represented the drug reaction possible. Non-linear optical properties were characterized from SHG efficiency measurements experimentally and the NLO parameters are also calculated from the optimized structure. The reactive sites within the molecule are detailed from the MEP surface maps. The molecular docking studies evident the structure-activity of the ionic cocrystal for anti-cancer drug property.

Peskütenin Kimyasal ve Mikrobiyolojik Özellikleri Üzerine bir Araştırma

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Ahmet Kurt

2015-02-01

Full Text Available Bu araştırmada Sivas ili ve çevresinden şansa bağlı olarak alınan 14 adet Pesküten örneği üzerinde kimyasal ve mikrobiyolojik araştırmalar yapılmıştır. Belirlenen değerler ortalama olarak şöyledir: Kurumaddede %30.96, su %69.04, yağ %3.66, yağsız kurumadde %27.30, toplam kül %4.92, kurumaddede kül %15.95, kurumaddede tuz %12.18, saf kül %1.13, protein %22.08, şeker ve benzerleri %0.295 ve asitlik derecesi 83.90 SH olmuştur. Bunun yanında ortalama mikrobiyolojik içerik; toplam bakteri sayısı 3.735x106/g, koliform bakteri sayısı 5.69x104/g, maya ve küf sayısı 1.398x104/g, laktik bakteri sayısı 1.997x106/g, proteolitik bakteri sayısı, 12.34x104/g ve lipolitik bakteri sayısı 10.14x104/g olarak belirlenmiştir.

A DETAILED MORPHO-KINEMATIC MODEL OF THE ESKIMO, NGC 2392: A UNIFYING VIEW WITH THE CAT'S EYE AND SATURN PLANETARY NEBULAE

International Nuclear Information System (INIS)

García-Díaz, Ma. T.; López, J. A.; Steffen, W.; Richer, M. G.

2012-01-01

The three-dimensional and kinematic structure of the Eskimo nebula, NGC 2392, has been notoriously difficult to interpret in detail given its complex morphology, multiple kinematic components and its nearly pole-on orientation along the line of sight. We present a comprehensive, spatially resolved, high-resolution, long-slit spectroscopic mapping of the Eskimo planetary nebula. The data consist of 21 spatially resolved, long-slit echelle spectra tightly spaced over the Eskimo and along its bipolar jets. This data set allows us to construct a velocity-resolved [N II] channel map of the nebula with a resolution of 10 km s –1 that disentangles its different kinematic components. The spectroscopic information is combined with Hubble Space Telescope images to construct a detailed three-dimensional morpho-kinematic model of the Eskimo using the code SHAPE. With this model we demonstrate that the Eskimo is a close analog to the Saturn and the Cat's Eye nebulae, but rotated 90° to the line of sight. Furthermore, we show that the main characteristics of our model apply to the general properties of the group of elliptical planetary nebulae with ansae or FLIERS, once the orientation is considered. We conclude that this kind of nebula belongs to a class with a complex common evolutionary sequence of events.

Autoradiographic Study of Incorporation of Tritiated Thymidine in the Rat; Etude Autoradiographique de l'Incorporation de Thymidine Tritiee chez le Rat; 0420 0430 0434 0438 043e 0430 0432 0442 043e 0414 ; Estudio Autorradiografico de la Incorporacion de Timidina Tritiada en la Rata

Energy Technology Data Exchange (ETDEWEB)

Maldague, P.; Hong-Que, Pham; Maisin, J. [Laboratoire de Radiobiologie, Institut du Cancer, Louvain (Belgium)

1962-02-15

The authors used tritiated thymidine to evaluate desoxyribonucleic acid synthesis in various rat organs. They show by autoradiographs that this synthesis takes place mainly in tissue having intensive mitotic activity (bone marrow, seminiferous tubules of the testis, mucous membrane of the intestine, oesophagus and tongue). The authors also studied the regeneration of the convoluted renal tubules during the months following local irradiation of the kidney at various doses. (author) [French] Les auteurs ont utilise de la thymidine tritiee pour evaluer la synthese de l'acide desoxyribonucleique au niveau de differents organes chez le rat. Ils montrent par autoradiographies que cette synthese s'effectue principalement au niveau des tissus presentant une activite mitotique intense (moelle osseuse, tubes seminiferes du testicule, muqueuse intestinale, oesophagienne et de la lingue). Les auteurs ont en outre etudie la regeneration des tubes contournes du rein apres irradiation locale de cet organe, a differentes doses et dans les mois qui suivent cette irradiation. (author) [Spanish] Los autores han utilizado timidina tritiada para evaluar la sintesis del acido desoxirribonucleico en distintos organos de la rata. Demuestran mediante autorradiografias que esta sintesis se produce principalmente en los tejidos de intensa actividad mitotica (medula osea, tubos seminiferos de los testiculos, mucosas intestinal, del esofago y de la lengua). Finalmente, los autores han estudiado la regeneracion de los tubos y convolvulados del rinon en los meses que siguen a la irradiacion local de este organo con distintas dosis. (author) [Russian] Avtory pol'zovalis' mechennym tritiem timidinom dlja ocenki sin- teza dezoksiribonukleinovoj kisloty v razlichnyh organah krysy. Pri po- moshhi radioavtografii avtory pokazyvajut, chto jetot sintez proishodit glavnym obrazom v tkanjah s intensivnoj mitoticheskoj dejatel'nost'ju (kostnyj mozg, semenenosnye kanaly testikula, slizistaja obolochka

Synthesis of Ethylene or Propylene/1,3-Butadiene Copolymers Possessing Pendant Vinyl Groups with Virtually No Internal Olefins

Directory of Open Access Journals (Sweden)

Kenji Michiue

2015-11-01

Full Text Available In general, ethylene/1,3-butadiene copolymerizations provides copolymers possessing both pendant vinyls and vinylenes as olefinic moieties. We, at MCI, studied the substituent effects of C2-symmetric zirconocene complexes, rac-[Me2Si(Indenyl’2]ZrCl2 (Indenyl’ = generic substituted indenyl, after activation on the ratio of the pendant vinyls and vinylenes of the resultant copolymers. Complexes examined in this study were rac-dimethylsilylbis (1-indenylzirconium dichloride (1, rac-dimethylsilyl-bis[1-(2-methyl-4,5-benzoindenyl] zirconium dichloride (2, rac-dimethylsilyl-bis[l-(2-methyl -4-phenylindenyl]zirconium dichloride (3, rac-dimethy1si1y1- bis(2-ethyl-4-phenylindenyl zirconium dichloride (4, rac-dimethylsilyl-bis[l-(2-n-propyl -4-(1-naphthylindenyl]zirconium dichloride (5, rac-dimethylsilyl-[1-(2-ethyl-4-(5-(2,2-dimethyl-2,3-dihydro-1H-cyclopenta [a]naphthalenylindenyl][1-(2-n-propyl-4-(5-(2,2-dimethyl-2,3-dihydro-1H-cyclopenta[a] naphthalenylindenyl]zirconium dichloride (6, rac-dimethylsilyl-bis[1-(2-ethyl-4-(9-phenanthrylindenyl]zirconium dichloride (7, and rac-dimethylsilyl-bis[l-(2-n-propyl-4-(9-phenanthrylindenyl]zirconium dichloride (8. We found that the ratio of the pendant vinyls and vinylenes is strongly affected by the bulkiness of the substituent on the complexes examined. The vinyl content increased linearly in the following order, 8 > 7 > 6 > 5 > 4 > 3 > 2 > 1. Notably, complex 8/DMAO formed ethylene/1,3-butadiene copolymers possessing predominant vinyl groups, which can be crucial precursors for functionalized polyolefins. Likewise, complex 8/DMAO afforded propylene/1,3-butadiene copolymers with predominant vinyl groups.

Organoactinides-new type of catalysts for carbon-silicon bond formation

International Nuclear Information System (INIS)

Dash, Aswini K.; Wang, Ji.Q.; Wang, Jiaxi; Gourevich, Ilya; Eisen, Moris S.

2002-01-01

Organoactinide complexes of the type Cp 2 * AnMe 2 (An=Th, U) have been found to be efficient catalysts for the hydrosilylation of terminal alkynes. The chemoselectivity and regiospecificity of the reactions depend strongly on the nature of the catalyst, the nature of the alkyne, the silane substituents, the ratio between the silane and alkyne, the solvent and the reaction temperature. The hydrosilylation reaction of the terminal alkynes with PhSiH 3 at room temperature produces the trans-vinylsilane as the major product along with the silylalkyne and the corresponding alkene. At higher temperatures the cis-vinylsilane and the double hydrosilylated alkene, in which the two silicon moieties are connected at the same carbon atom, are also obtained. Replacing the pentamethylcyclopentadienyl ligand by the bridge ligation [Me 2 SiCp'' 2 ] 2- 2[Li] + (Cp''=C 5 Me 4 ) affords the synthesis of ansa-Me 2 SiCp'' 2 ThBu 2 , which was found to react extremely fast for the hydrosilylation of terminal alkynes or alkenes with PhSiH 3 . Besides the rapidity of the processes using the bridge organoactinide, as compared to Cp * 2 ThMe 2 , the chemo- and regio-selectivity of the products were increased allowing the production of only the trans-vinylsilane and the 1-silylated alkane for the hydrosilylation of alkyne and alkene, respectively. (author)

Control of π-Electron Rotations in Chiral Aromatic Molecules Using Intense Laser Pulses

Science.gov (United States)

Kanno, Manabu; Kono, Hirohiko; Fujimura, Yuichi

Our recent theoretical studies on laser-induced π-electron rotations in chiral aromatic molecules are reviewed. π electrons of a chiral aromatic molecule can be rotated along its aromatic ring by a nonhelical, linearly polarized laser pulse. An ansa aromatic molecule with a six-membered ring, 2,5-dichloro[n](3,6) pyrazinophane, which belongs to a planar-chiral molecule group, and its simplified molecule 2,5-dichloropyrazine are taken as model molecules. Electron wavepacket simulations in the frozen-molecular-vibration approximation show that the initial direction of π-electron rotation depends on the polarization direction of a linearly polarized laser pulse applied. Consecutive unidirectional rotation can be achieved by applying a sequence of linearly polarized pump and dump pulses to prevent reverse rotation. Optimal control simulations of π-electron rotation show that another controlling factor for unidirectional rotation is the relative optical phase between the different frequency components of an incident pulse in addition to photon polarization direction. Effects of nonadiabatic coupling between π-electron rotation and molecular vibrations are also presented, where the constraints of the frozen approximation are removed. The angular momentum gradually decays mainly owing to nonadiabatic coupling, while the vibrational amplitudes greatly depend on their rotation direction. This suggests that the direction of π-electron rotation on an attosecond timescale can be identified by detecting femtosecond molecular vibrations.

[Motor nerves of the face. Surgical and radiologic anatomy of facial paralysis and their surgical repair].

Science.gov (United States)

Vacher, C; Cyna-Gorse, F

2015-10-01

Motor innervation of the face depends on the facial nerve for the mobility of the face, on the mandibular nerve, third branch of the trigeminal nerve, which gives the motor innervation of the masticator muscles, and the hypoglossal nerve for the tongue. In case of facial paralysis, the most common palliative surgical techniques are the lengthening temporalis myoplasty (the temporal is innervated by the mandibular nerve) and the hypoglossal-facial anastomosis. The aim of this work is to describe the surgical anatomy of these three nerves and the radiologic anatomy of the facial nerve inside the temporal bone. Then the facial nerve penetrates inside the parotid gland giving a plexus. Four branches of the facial nerve leave the parotid gland: they are called temporal, zygomatic, buccal and marginal which give innervation to the cutaneous muscles of the face. Mandibular nerve gives three branches to the temporal muscles: the anterior, intermediate and posterior deep temporal nerves which penetrate inside the deep aspect of the temporal muscle in front of the infratemporal line. The hypoglossal nerve is only the motor nerve to the tongue. The ansa cervicalis, which is coming from the superficial cervical plexus and joins the hypoglossal nerve in the submandibular area is giving the motor innervation to subhyoid muscles and to the geniohyoid muscle. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Intraoperative Hypoglossal Nerve Mapping During Carotid Endarterectomy: Technical Note.

Science.gov (United States)

Kojima, Atsuhiro; Saga, Isako; Ishikawa, Mami

2018-05-01

Hypoglossal nerve deficit is a possible complication caused by carotid endarterectomy (CEA). The accidental injury of the hypoglossal nerve during surgery is one of the major reasons for permanent hypoglossal nerve palsy. In this study, we investigated the usefulness of intraoperative mapping of the hypoglossal nerve to identify this nerve during CEA. Five consecutive patients who underwent CEA for the treatment of symptomatic or asymptomatic carotid artery stenosis were studied. A hand-held probe was used to detect the hypoglossal nerve in the operative field, and the tongue motor evoked potentials (MEPs) were recorded. The tongue MEPs were obtained in all the patients. The invisible hypoglossal nerve was successfully identified without any difficulty when the internal carotid artery was exposed. Intraoperative mapping was particularly useful for identifying the hypoglossal nerve when the hypoglossal nerve passed beneath the posterior belly of the digastric muscle. In 1 of 2 cases, MEP was also elicited when the ansa cervicalis was stimulated, although the resulting amplitude was much smaller than that obtained by direct stimulation of the hypoglossal nerve. Postoperatively, none of the patients presented with hypoglossal nerve palsy. Intraoperative hypoglossal nerve mapping enabled us to locate the invisible hypoglossal nerve during the exposure of the internal carotid artery accurately without retracting the posterior belly of the digastric muscle and other tissues in the vicinity of the internal carotid artery. Copyright © 2018 Elsevier Inc. All rights reserved.

YOUNG PLANETARY NEBULAE: HUBBLE SPACE TELESCOPE IMAGING AND A NEW MORPHOLOGICAL CLASSIFICATION SYSTEM

International Nuclear Information System (INIS)

Sahai, Raghvendra; Villar, Gregory G.; Morris, Mark R.

2011-01-01

Using Hubble Space Telescope images of 119 young planetary nebulae (PNs), most of which have not previously been published, we have devised a comprehensive morphological classification system for these objects. This system generalizes a recently devised system for pre-planetary nebulae, which are the immediate progenitors of PNs. Unlike previous classification studies, we have focused primarily on young PNs rather than all PNs, because the former best show the influences or symmetries imposed on them by the dominant physical processes operating at the first and primary stage of the shaping process. Older PNs develop instabilities, interact with the ambient interstellar medium, and are subject to the passage of photoionization fronts, all of which obscure the underlying symmetries and geometries imposed early on. Our classification system is designed to suffer minimal prejudice regarding the underlying physical causes of the different shapes and structures seen in our PN sample, however, in many cases, physical causes are readily suggested by the geometry, along with the kinematics that have been measured in some systems. Secondary characteristics in our system, such as ansae, indicate the impact of a jet upon a slower-moving, prior wind; a waist is the signature of a strong equatorial concentration of matter, whether it be outflowing or in a bound Keplerian disk, and point symmetry indicates a secular trend, presumably precession, in the orientation of the central driver of a rapid, collimated outflow.

Reinnervation of the diaphragm by the inferior laryngeal nerve to the phrenic nerve in ventilator-dependent tetraplegic patients with C3-5 damage.

Science.gov (United States)

Verin, Eric; Morelot-Panzini, Capucine; Gonzalez-Bermejo, Jesus; Veber, Benoit; Perrouin Verbe, Brigitte; Soudrie, Brigitte; Leroi, Anne Marie; Marie, Jean Paul; Similowski, Thomas

2017-10-01

The aim of this study was to evaluate the feasibility of unilateral diaphragmatic reinnervation in humans by the inferior laryngeal nerve. This pilot study included chronically ventilated tetraplegic patients with destruction of phrenic nerve motoneurons. Five patients were included. They all had a high level of tetraplegia, with phrenic nerve motor neuron destruction. They were highly dependent on ventilation, without any possibility of weaning. They did not have other chronic pathologies, especially laryngeal disease. They all had diaphragmatic explorations to diagnose the destruction of the motoneurons of the phrenic nerves and nasoendoscopy to be sure that they did not have laryngeal or pharyngeal disease. Then, surgical anastomosis of the right phrenic nerve was performed with the inferior laryngeal nerve, by a cervical approach. A laryngeal reinnervation was performed at the same time, using the ansa hypoglossi. One patient was excluded because of a functional phrenic nerve and one patient died 6 months after the surgery of a cardiac arrest. The remaining three patients were evaluated after the anastomosis every 6 months. They did not present any swallowing or vocal alterations. In these three patients, the diaphragmatic explorations showed that there was a recovery of the diaphragmatic electromyogram of the right and left hemidiaphragms after 1 year. Two patients had surgical diaphragmatic explorations for diaphragmatic pacing 18-24 months after the reinnervation with excellent results. At 36 months, none of the patients could restore their automatic ventilation. In conclusion, this study demonstrated that diaphragmatic reinnervation by the inferior laryngeal nerve is effective, without any vocal or swallowing complications.

Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs.

Science.gov (United States)

Cardinal, René; Pagé, Pierre; Vermeulen, Michel; Bouchard, Caroline; Ardell, Jeffrey L; Foreman, Robert D; Armour, J Andrew

2006-11-01

Spinal cord stimulation (SCS) applied to the dorsal aspect of the cranial thoracic cord imparts cardioprotection under conditions of neuronally dependent cardiac stress. This study investigated whether neuronally induced atrial arrhythmias can be modulated by SCS. In 16 anesthetized dogs with intact stellate ganglia and in five with bilateral stellectomy, trains of five electrical stimuli were delivered during the atrial refractory period to right- or left-sided mediastinal nerves for up to 20 s before and after SCS (20 min). Recordings were obtained from 191 biatrial epicardial sites. Before SCS (11 animals), mediastinal nerve stimulation initiated bradycardia alone (12 nerve sites), bradycardia followed by tachyarrhythmia/fibrillation (50 sites), as well as tachyarrhythmia/fibrillation without a preceding bradycardia (21 sites). After SCS, the number of responsive sites inducing bradycardia was reduced by 25% (62 to 47 sites), and the cycle length prolongation in residual bradycardias was reduced. The number of responsive sites inducing tachyarrhythmia was reduced by 60% (71 to 29 sites). Once elicited, residual tachyarrhythmias arose from similar epicardial foci, displaying similar dynamics (cycle length) as in control states. In the absence of SCS, bradycardias and tachyarrhythmias induced by repeat nerve stimulation were reproducible (five additional animals). After bilateral stellectomy, SCS no longer influenced neuronal induction of bradycardia and atrial tachyarrhythmias. These data indicate that SCS obtunds the induction of atrial arrhythmias resulting from excessive activation of intrinsic cardiac neurons and that such protective effects depend on the integrity of nerves coursing via the subclavian ansae and stellate ganglia.

Catalytic effect in opening the coordination sphere of an organo-f-complex

International Nuclear Information System (INIS)

Andrea, T.; Wang, J.; Gourevich, I.; Eisen, M.S.

2002-01-01

Organo-f-complexes have been studied in the last decade showing unique stoichiometric and catalytic properties, which are deeply influenced by the nature of the x ancillary ligands. Opening of the metal center coordination sphere is obtained by replacing the pentamethylcyclopentadienyl ligation in Cp* 2 MR 2 (Cp* = C 5 Me 5 , M = f-element metal, R = a-bonded ligand) by the bridged ancillary ligation Anna-Me 2 SiCp 2MR 2 (Cp* = C 5 Me 4 ). For organolanthanides, this change allows an increase (10-100 fold) in rates for the olefin insertion into the M-R bond [1] and in organoactinides; this modification has been shown to cause an increase (103 fold) in their catalytic activity for the hydrogenation of 1-hexene [2]. Recently, we have shown that organoactinides of the type Cp* 2 MR 2 (Cp* = C 5 Me 5 ; M = Th, U; R = CH 3 ) are active catalysts for both the oligomerization and hydrosilylation of terminal alkynes [3J. Thus, a conceptual question arises regarding the use of an open organoactinide such as Me 2 SiCp* 2 U n Bu 2 as compared to Cp* 2 UR 2 . This opening in the coordination sphere at the metal center should be unique in such a way that it is reasonable expected the increase of the reactivity towards product formation in the hydrosilylation and metathesis catalytic processes of terminal alkynes. In this poster we report, and quantitatively compare, the effects of the ansa-organouranium complex (Me 2 SiCp'' 2 U n Bu) 2 O The synthesis of the complex was achieved as described in equations 1 and 2

Fuzzy knowledge bases integration based on ontology

OpenAIRE

Ternovoy, Maksym; Shtogrina, Olena

2012-01-01

the paper describes the approach for fuzzy knowledge bases integration with the usage of ontology. This approach is based on metadata-base usage for integration of different knowledge bases with common ontology. The design process of metadata-base is described.

Foundation: Transforming data bases into knowledge bases

Science.gov (United States)

Purves, R. B.; Carnes, James R.; Cutts, Dannie E.

1987-01-01

One approach to transforming information stored in relational data bases into knowledge based representations and back again is described. This system, called Foundation, allows knowledge bases to take advantage of vast amounts of pre-existing data. A benefit of this approach is inspection, and even population, of data bases through an intelligent knowledge-based front-end.

Juditos ir Salomėjos mitologinių įvaizdžių metamorfozė: nuo antitezės iki sintezės = The metamorphosis of Judith's and Salome's mythological images: from antithesis to synthesis

OpenAIRE

Jekentaitė-Kuzmickienė, Leonarda

2006-01-01

The famous representative of the Vienna Secession, Gustav Klimt, painted two pictures that show a beautiful woman holding a man’s head in her hand. The paintings are called Judith I and Judith II, but sometimes one of them is called ‘Salome’. This article uses Biblical mythology as the basis of an analysis of the paradoxical coalescing of these two different characters. Judith – a Jewish heroine – has seduced and killed Holofern to save her nation from inevitable destruction. In the Old Testa...

Case-based reasoning: The marriage of knowledge base and data base

Science.gov (United States)

Pulaski, Kirt; Casadaban, Cyprian

1988-01-01

The coupling of data and knowledge has a synergistic effect when building an intelligent data base. The goal is to integrate the data and knowledge almost to the point of indistinguishability, permitting them to be used interchangeably. Examples given in this paper suggest that Case-Based Reasoning is a more integrated way to link data and knowledge than pure rule-based reasoning.

Synthesis of the phase with T sub c =110 K in Bi(Pb)-Sr-Ca-Cu-O superconducting ceramics. Sintez fazy T sub c =110 K sverkhprovodyashchej keramiki sostava Bi(Pb)-Sr-Ca-Cu-O

Energy Technology Data Exchange (ETDEWEB)

Dubovitskij, A V; Makarov, E F; Makova, M K; Merzhanov, V A; Topnikov, V N [AN SSSR, Moscow (USSR). Inst. Khimicheskoj Fiziki

1991-05-01

Synthesis of 110 K single-phase bismuth ceramics (BiPb){sub 2}Sr{sub 2}Ca{sub n-1}Cu{sub n}O{sub x} was conducted in narrow temperature and time range. Diffusion of bismuth ions is proposed to be the decisive factor of synthesis of bismuth ceramics. The diffusion depends on prehistory of basic burden preparation and on its dispersivity and homogeneity in particluar. Optimal time of synthesis for lead doped ceramics of 2223 composition, synthesized from initial nitrate components, is equal to 65 h at 850 deg C. The role of Pb{sup 2+} ions is probably reduced to decrease of diffusion mobility of Bi{sup 3+} ions over the bismuth sublattice. Ceramics doping with CdO and CdCl{sub 2} compounds instead of lead stabilizes superconductivity in bismuth ceramics, but with worth superconducting parameters.

From oil-based mud to water-based mud

International Nuclear Information System (INIS)

Christiansen, C.

1991-01-01

Maersk Olie og Gas AS has used low toxic oil-based muds extensively since 1982 for drilling development wells and later in the development of horizontal well drilling techniques. However, in view of the strong drive towards a reduction in the amount of oil discharged to the North Sea from the oil industry, Maersk Olie og Gas AS initiated trials with new or improved types of water-based mud, first in deviated wells (1989) and then in horizontal wells (1990). The paper reviews Maersk Olie og Gas As experience with oil-based mud since the drilling of the first horizontal well in 1987, specifically with respect to cuttings washing equipment, oil retention on cuttings, and the procedure for monitoring of this parameter. It describes the circumstances leading to the decision to revert to water-based mud systems. Finally, it reviews the experience gained so far with the new improved types of water-based mud systems, mainly glycol and KCl/polymer mud systems. Comparison of operational data, such as rate of penetration, torque and drag, etc., is made between wells drilled with oil-based mud and water-based mud. The trials with the new improved types of water-based mud systems have been positive, i.e. horizontal wells can be drilled successfully with water-based mud. As a result, Maersk Olie og and Gas AS has decided to discontinue the use of low toxic oil-based muds in the Danish sector of the North Sea

Computer-based multi-channel analyzer based on internet

International Nuclear Information System (INIS)

Zhou Xinzhi; Ning Jiaoxian

2001-01-01

Combined the technology of Internet with computer-based multi-channel analyzer, a new kind of computer-based multi-channel analyzer system which is based on browser is presented. Its framework and principle as well as its implementation are discussed

Combining Host-based and network-based intrusion detection system

African Journals Online (AJOL)

These attacks were simulated using hping. The proposed system is implemented in Java. The results show that the proposed system is able to detect attacks both from within (host-based) and outside sources (network-based). Key Words: Intrusion Detection System (IDS), Host-based, Network-based, Signature, Security log.

NMR studies concerning base-base interactions in oligonucleotides

International Nuclear Information System (INIS)

Hoogen, Y.T. van den.

1988-01-01

Two main subjects are treated in the present thesis. The firsst part principally deals with the base-base interactions in single-stranded oligoribonucleotides. The second part presents NMR and model-building studies of DNA and RNA duplexes containing an unpaired base. (author). 242 refs.; 26 figs.; 24 tabs

XML-Based SHINE Knowledge Base Interchange Language

Science.gov (United States)

James, Mark; Mackey, Ryan; Tikidjian, Raffi

2008-01-01

The SHINE Knowledge Base Interchange Language software has been designed to more efficiently send new knowledge bases to spacecraft that have been embedded with the Spacecraft Health Inference Engine (SHINE) tool. The intention of the behavioral model is to capture most of the information generally associated with a spacecraft functional model, while specifically addressing the needs of execution within SHINE and Livingstone. As such, it has some constructs that are based on one or the other.

Communication Base Station Log Analysis Based on Hierarchical Clustering

Directory of Open Access Journals (Sweden)

Zhang Shao-Hua

2017-01-01

Full Text Available Communication base stations generate massive data every day, these base station logs play an important value in mining of the business circles. This paper use data mining technology and hierarchical clustering algorithm to group the scope of business circle for the base station by recording the data of these base stations.Through analyzing the data of different business circle based on feature extraction and comparing different business circle category characteristics, which can choose a suitable area for operators of commercial marketing.

Value-based metrics and Internet-based enterprises

Science.gov (United States)

Gupta, Krishan M.

2001-10-01

Within the last few years, a host of value-based metrics like EVA, MVA, TBR, CFORI, and TSR have evolved. This paper attempts to analyze the validity and applicability of EVA and Balanced Scorecard for Internet based organizations. Despite the collapse of the dot-com model, the firms engaged in e- commerce continue to struggle to find new ways to account for customer-base, technology, employees, knowledge, etc, as part of the value of the firm. While some metrics, like the Balance Scorecard are geared towards internal use, others like EVA are for external use. Value-based metrics are used for performing internal audits as well as comparing firms against one another; and can also be effectively utilized by individuals outside the firm looking to determine if the firm is creating value for its stakeholders.

Integrated Case Based and Rule Based Reasoning for Decision Support

OpenAIRE

Eshete, Azeb Bekele

2009-01-01

This project is a continuation of my specialization project which was focused on studying theoretical concepts related to case based reasoning method, rule based reasoning method and integration of them. The integration of rule-based and case-based reasoning methods has shown a substantial improvement with regards to performance over the individual methods. Verdande Technology As wants to try integrating the rule based reasoning method with an existing case based system. This project focu...

Fossil isotope records of seasonal climate and ecology: Straight from the horse's mouth

Science.gov (United States)

Sharp, Z. D.; Cerling, T. E.

1998-03-01

Isotope analysis of a bulk fossil tooth gives a “snapshot” impression of paleoclimatic conditions—a single point in time. However, hypsodont teeth grow over a period of a year or more, so that stable carbon and oxygen isotope variations along their length are a “tape recorder” of short-term seasonal variations from the distant past. We have used a new in situ micro-laser sampling method to determine submillimeter carbon and oxygen isotope variations in the enamel of individual fossil horse teeth to assess ancient annual meteoric water variations and feeding patterns. The δ18O values from a 6.8 Ma fossil horse tooth (Astrohippus ansae) from Texas vary cyclically along the 6 cm length of the tooth with a smoothed amplitude of >4‰, similar to the monthly averaged amplitude measured in modern meteoric waters from the region. The seasonal δ18O values are ˜3‰ to 4‰ higher than those calculated from modern meteoric water data, suggesting either a higher local meteoric water value in the Miocene of Texas, or that the animal received a high proportion of its dietary water from plants or highly evaporated water. A Holocene horse tooth from the shores of Glacial Lake Agassiz, North Dakota (Equus sp.), also has isotopic variations with the same 35 mm periodicity, but a smoothed amplitude of only 2‰. This horse most likely had a buffered drinking supply. The calculated δ18O of the water in equilibrium with this tooth is the same as the modern measured annual average. The variations within a single tooth can be as large as those generally observed in entire stratigraphic sections of fossil teeth analyzed by bulk methods. The new method provides an important technique for evaluating fossil diagenesis; conventional bulk analyses of teeth fragments may not be representative of the whole tooth, thus explaining analytical scatter that has been previously attributed to diagenesis.

Strong adsorbability of mercury ions on aniline/sulfoanisidine copolymer nanosorbents.

Science.gov (United States)

Li, Xin-Gui; Feng, Hao; Huang, Mei-Rong

2009-01-01

The highest Hg-ion adsorbance so far, namely up to 2063 mg g(-1), has been achieved by poly(aniline-co-5-sulfo-2-anisidine) nanosorbents. Sorption of Hg ions occurs mainly by redox and chelation mechanisms (see scheme), but also by ion exchange and physisorption.Poly(aniline (AN)-co-5-sulfo-2-anisidine (SA)) nanoparticles were synthesized by chemical oxidative copolymerization of AN and SA monomers, and their extremely strong adsorption of mercury ions in aqueous solution was demonstrated. The reactivity ratios of AN and SA comonomers were found to be 2.05 and 0.02, respectively. While AN monomer tends to homopolymerize, SA monomer tends to copolymerize with AN monomer because of the great steric hindrance and electron-attracting effect of the sulfo groups, despite the effect of conjugation of the methoxyl group with the benzene ring. The effects of initial mercury(II) concentration, sorption time, sorption temperature, ultrasonic treatment, and sorbent dosage on mercury-ion sorption onto AN/SA (50/50) copolymer nanoparticles with a number-average diameter of around 120 nm were significantly optimized. The results show that the maximum Hg-ion sorption capacity on the particulate nanosorbents can even reach 2063 mg of Hg per gram of sorbent, which would be the highest Hg-ion adsorbance so far. The sorption data fit to the Langmuir isotherm, and the process obeys pseudo-second-order kinetics. The IR and UV/Vis spectral data of the Hg-loaded copolymer particles suggest that some mercury(II) was directly reduced by the copolymer to mercury(I) and even mercury(0). A mechanism of sorption between the particles and Hg ions in aqueous solution is proposed, and a physical/ion exchange/chelation/redox sorption ratio of around 2/3/45/50 was found. Copolymer nanoparticles may be one of the most powerful and cost-effective sorbents of mercury ions, with a wide range of potential applications for the efficient removal and even recovery of the mercury ions from aqueous solution.

Fístula de alto gasto High output fistula

Directory of Open Access Journals (Sweden)

Ricardo Almeida Varela

2012-06-01

Full Text Available Se presenta a un paciente de 37 años de edad que acude a nuestro Cuerpo de Guardia politraumatizado, con lesiones torácicas y abdominales, con síntomas y signos sugestivos de fracturas costales múltiples, con hemotórax derecho y hemoperitoneo, corroborado imaginológicamente y en la punción abdominal. Se realiza pleurostomía mínima intermedia y laparotomía exploratoria. Se le encuentran lesiones hepáticas de los segmentos VI, V, VIII y IV, con una profundidad mayor de 3 cm, además, deserosamientos en las asas delgadas intestinales y colon. Se realiza hepatorrafia y empaquetamiento hepático. Posteriormente van apareciendo complicaciones, por lo que tiene que ser reintervenido en más de 60 ocasiones. Entre ellas, la aparición de una fístula de alto gasto, que lo llevó a la desnutrición y a la permanencia con el abdomen expuesto durante 7 meses hasta el egreso. Se revisa la literatura correspondiente a estas entidades.A 37 years-old multi-traumatized male patient went to our emergency service. He had many injures in the thorax and the abdomen, together with symptoms and signs suggestive of multiple costal fractures, with right hemothorax and hemoperitoneum, all of which was confirmed by imaging techniques and by abdominal puncture. Minimal intermediate pleurostomy and exploratory laparoscopy were performed. We found hepatic lesions in the 6th, 5th, 8th and 4th segments, over 3 cm deep; additionally, the loss of serosa from the intestinal ansae and from the colon. Hepatorrhaphy and hepatic packing were also performed. Later on, more complications appeared, so he had to be re-operated more than 60 times. The occurrence of a high output fistula led him to malnutrition and his abdomen remained exposed for 7 months until he was finally discharged from hospital. This paper also presented a literature review on this topic.

Knowledge base verification based on enhanced colored petri net

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Hyun; Seong, Poong Hyun [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

1998-12-31

Verification is a process aimed at demonstrating whether a system meets it`s specified requirements. As expert systems are used in various applications, the knowledge base verification of systems takes an important position. The conventional Petri net approach that has been studied recently in order to verify the knowledge base is found that it is inadequate to verify the knowledge base of large and complex system, such as alarm processing system of nuclear power plant. Thus, we propose an improved method that models the knowledge base as enhanced colored Petri net. In this study, we analyze the reachability and the error characteristics of the knowledge base and apply the method to verification of simple knowledge base. 8 refs., 4 figs. (Author)

Knowledge base verification based on enhanced colored petri net

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Hyun; Seong, Poong Hyun [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

1997-12-31

Verification is a process aimed at demonstrating whether a system meets it`s specified requirements. As expert systems are used in various applications, the knowledge base verification of systems takes an important position. The conventional Petri net approach that has been studied recently in order to verify the knowledge base is found that it is inadequate to verify the knowledge base of large and complex system, such as alarm processing system of nuclear power plant. Thus, we propose an improved method that models the knowledge base as enhanced colored Petri net. In this study, we analyze the reachability and the error characteristics of the knowledge base and apply the method to verification of simple knowledge base. 8 refs., 4 figs. (Author)

Computer-based and web-based radiation safety training

Energy Technology Data Exchange (ETDEWEB)

Owen, C., LLNL

1998-03-01

The traditional approach to delivering radiation safety training has been to provide a stand-up lecture of the topic, with the possible aid of video, and to repeat the same material periodically. New approaches to meeting training requirements are needed to address the advent of flexible work hours and telecommuting, and to better accommodate individuals learning at their own pace. Computer- based and web-based radiation safety training can provide this alternative. Computer-based and web- based training is an interactive form of learning that the student controls, resulting in enhanced and focused learning at a time most often chosen by the student.

Content-Based Image Retrial Based on Hadoop

Directory of Open Access Journals (Sweden)

DongSheng Yin

2013-01-01

Full Text Available Generally, time complexity of algorithms for content-based image retrial is extremely high. In order to retrieve images on large-scale databases efficiently, a new way for retrieving based on Hadoop distributed framework is proposed. Firstly, a database of images features is built by using Speeded Up Robust Features algorithm and Locality-Sensitive Hashing and then perform the search on Hadoop platform in a parallel way specially designed. Considerable experimental results show that it is able to retrieve images based on content on large-scale cluster and image sets effectively.

Home-based versus centre-based cardiac rehabilitation.

Science.gov (United States)

Taylor, Rod S; Dalal, Hayes; Jolly, Kate; Moxham, Tiffany; Zawada, Anna

2010-01-20

The burden of cardiovascular disease world-wide is one of great concern to patients and health care agencies alike. Traditionally centre-based cardiac rehabilitation (CR) programmes are offered to individuals after cardiac events to aid recovery and prevent further cardiac illness. Home-based cardiac rehabilitation programmes have been introduced in an attempt to widen access and participation. To determine the effectiveness of home-based cardiac rehabilitation programmes compared with supervised centre-based cardiac rehabilitation on mortality and morbidity, health-related quality of life and modifiable cardiac risk factors in patients with coronary heart disease. We updated the search of a previous review by searching the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2007, Issue 4), MEDLINE, EMBASE and CINAHL from 2001 to January 2008. We checked reference lists and sought advice from experts. No language restrictions were applied. Randomised controlled trials (RCTs) that compared centre-based cardiac rehabilitation (e.g. hospital, gymnasium, sports centre) with home-based programmes, in adults with myocardial infarction, angina, heart failure or who had undergone revascularisation. Studies were selected independently by two reviewers, and data extracted by a single reviewer and checked by a second one. Authors were contacted where possible to obtain missing information. Twelve studies (1,938 participants) met the inclusion criteria. The majority of studies recruited a lower risk patient following an acute myocardial infarction (MI) and revascularisation. There was no difference in outcomes of home- versus centre-based cardiac rehabilitation in mortality risk ratio (RR) was1.31 (95% confidence interval (C) 0.65 to 2.66), cardiac events, exercise capacity standardised mean difference (SMD) -0.11 (95% CI -0.35 to 0.13), as well as in modifiable risk factors (systolic blood pressure; diastolic blood pressure; total cholesterol

14 CFR 119.47 - Maintaining a principal base of operations, main operations base, and main maintenance base...

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Maintaining a principal base of operations, main operations base, and main maintenance base; change of address. 119.47 Section 119.47 Aeronautics... Under Part 121 or Part 135 of This Chapter § 119.47 Maintaining a principal base of operations, main...

Model-Based Requirements Management in Gear Systems Design Based On Graph-Based Design Languages

Directory of Open Access Journals (Sweden)

Kevin Holder

2017-10-01

Full Text Available For several decades, a wide-spread consensus concerning the enormous importance of an in-depth clarification of the specifications of a product has been observed. A weak clarification of specifications is repeatedly listed as a main cause for the failure of product development projects. Requirements, which can be defined as the purpose, goals, constraints, and criteria associated with a product development project, play a central role in the clarification of specifications. The collection of activities which ensure that requirements are identified, documented, maintained, communicated, and traced throughout the life cycle of a system, product, or service can be referred to as “requirements engineering”. These activities can be supported by a collection and combination of strategies, methods, and tools which are appropriate for the clarification of specifications. Numerous publications describe the strategy and the components of requirements management. Furthermore, recent research investigates its industrial application. Simultaneously, promising developments of graph-based design languages for a holistic digital representation of the product life cycle are presented. Current developments realize graph-based languages by the diagrams of the Unified Modelling Language (UML, and allow the automatic generation and evaluation of multiple product variants. The research presented in this paper seeks to present a method in order to combine the advantages of a conscious requirements management process and graph-based design languages. Consequently, the main objective of this paper is the investigation of a model-based integration of requirements in a product development process by means of graph-based design languages. The research method is based on an in-depth analysis of an exemplary industrial product development, a gear system for so-called “Electrical Multiple Units” (EMU. Important requirements were abstracted from a gear system

Solid Base Catalysis

CERN Document Server

Ono, Yoshio

2011-01-01

The importance of solid base catalysts has come to be recognized for their environmentally benign qualities, and much significant progress has been made over the past two decades in catalytic materials and solid base-catalyzed reactions. The book is focused on the solid base. Because of the advantages over liquid bases, the use of solid base catalysts in organic synthesis is expanding. Solid bases are easier to dispose than liquid bases, separation and recovery of products, catalysts and solvents are less difficult, and they are non-corrosive. Furthermore, base-catalyzed reactions can be performed without using solvents and even in the gas phase, opening up more possibilities for discovering novel reaction systems. Using numerous examples, the present volume describes the remarkable role solid base catalysis can play, given the ever increasing worldwide importance of "green" chemistry. The reader will obtain an overall view of solid base catalysis and gain insight into the versatility of the reactions to whic...

Evidence-based monitoring and evaluation of the faith-based ...

African Journals Online (AJOL)

Background: The Islamic Medical Association of Uganda, has been implementing the faith-based approach to HIV prevention without baseline data on expected positive outcomes. Objectives: To establish evidence-based baseline data on expected positive outcomes of the faith-based approach to HIV prevention. Methods: ...

Covariance-Based Measurement Selection Criterion for Gaussian-Based Algorithms

Directory of Open Access Journals (Sweden)

Fernando A. Auat Cheein

2013-01-01

Full Text Available Process modeling by means of Gaussian-based algorithms often suffers from redundant information which usually increases the estimation computational complexity without significantly improving the estimation performance. In this article, a non-arbitrary measurement selection criterion for Gaussian-based algorithms is proposed. The measurement selection criterion is based on the determination of the most significant measurement from both an estimation convergence perspective and the covariance matrix associated with the measurement. The selection criterion is independent from the nature of the measured variable. This criterion is used in conjunction with three Gaussian-based algorithms: the EIF (Extended Information Filter, the EKF (Extended Kalman Filter and the UKF (Unscented Kalman Filter. Nevertheless, the measurement selection criterion shown herein can also be applied to other Gaussian-based algorithms. Although this work is focused on environment modeling, the results shown herein can be applied to other Gaussian-based algorithm implementations. Mathematical descriptions and implementation results that validate the proposal are also included in this work.

Model-Based Learning Environment Based on The Concept IPS School-Based Management

Directory of Open Access Journals (Sweden)

Hamid Darmadi

2017-03-01

Full Text Available The results showed: (1 learning model IPS-oriented environment can grow and not you love the cultural values of the area as a basis for the development of national culture, (2 community participation, and the role of government in implementing learning model of IPS-based environment provides a positive impact for the improvement of management school resources, (3 learning model IPS-based environment effectively creating a way of life together peacefully, increase the intensity of togetherness and mutual respect (4 learning model IPS-based environment can improve student learning outcomes, (5 there are differences in the expression of attitudes and results learning among students who are located in the area of conflict with students who are outside the area of conflict (6 analysis of the scale of attitudes among school students da SMA result rewards high school students to the values of unity and nation, respect for diversity and peaceful coexistence, It is recommended that the Department of Education authority as an institution of Trustees and the development of social and cultural values in the province can apply IPS learning model based environments.

A Web-Based Learning Support System for Inquiry-Based Learning

Science.gov (United States)

Kim, Dong Won; Yao, Jingtao

The emergence of the Internet and Web technology makes it possible to implement the ideals of inquiry-based learning, in which students seek truth, information, or knowledge by questioning. Web-based learning support systems can provide a good framework for inquiry-based learning. This article presents a study on a Web-based learning support system called Online Treasure Hunt. The Web-based learning support system mainly consists of a teaching support subsystem, a learning support subsystem, and a treasure hunt game. The teaching support subsystem allows instructors to design their own inquiry-based learning environments. The learning support subsystem supports students' inquiry activities. The treasure hunt game enables students to investigate new knowledge, develop ideas, and review their findings. Online Treasure Hunt complies with a treasure hunt model. The treasure hunt model formalizes a general treasure hunt game to contain the learning strategies of inquiry-based learning. This Web-based learning support system empowered with the online-learning game and founded on the sound learning strategies furnishes students with the interactive and collaborative student-centered learning environment.

Design of Composite Structures Using Knowledge-Based and Case Based Reasoning

Science.gov (United States)

Lambright, Jonathan Paul

1996-01-01

A method of using knowledge based and case based reasoning to assist designers during conceptual design tasks of composite structures was proposed. The cooperative use of heuristics, procedural knowledge, and previous similar design cases suggests a potential reduction in design cycle time and ultimately product lead time. The hypothesis of this work is that the design process of composite structures can be improved by using Case-Based Reasoning (CBR) and Knowledge-Based (KB) reasoning in the early design stages. The technique of using knowledge-based and case-based reasoning facilitates the gathering of disparate information into one location that is easily and readily available. The method suggests that the inclusion of downstream life-cycle issues into the conceptual design phase reduces potential of defective, and sub-optimal composite structures. Three industry experts were interviewed extensively. The experts provided design rules, previous design cases, and test problems. A Knowledge Based Reasoning system was developed using the CLIPS (C Language Interpretive Procedural System) environment and a Case Based Reasoning System was developed using the Design Memory Utility For Sharing Experiences (MUSE) xviii environment. A Design Characteristic State (DCS) was used to document the design specifications, constraints, and problem areas using attribute-value pair relationships. The DCS provided consistent design information between the knowledge base and case base. Results indicated that the use of knowledge based and case based reasoning provided a robust design environment for composite structures. The knowledge base provided design guidance from well defined rules and procedural knowledge. The case base provided suggestions on design and manufacturing techniques based on previous similar designs and warnings of potential problems and pitfalls. The case base complemented the knowledge base and extended the problem solving capability beyond the existence of

Feature-Based versus Category-Based Induction with Uncertain Categories

Science.gov (United States)

Griffiths, Oren; Hayes, Brett K.; Newell, Ben R.

2012-01-01

Previous research has suggested that when feature inferences have to be made about an instance whose category membership is uncertain, feature-based inductive reasoning is used to the exclusion of category-based induction. These results contrast with the observation that people can and do use category-based induction when category membership is…

[right] - DUST RING AROUND STAR OFFERS NEW CLUES INTO PLANET FORMATION

Science.gov (United States)

2002-01-01

A NASA Hubble Space Telescope false-color near infrared image of a novel type of structure seen in space - a dust ring around a star. Superficially resembling Saturn's rings -- but on a vastly larger scale -- the 'hula-hoop' around the star called HR 4796A offers new clues into the possible presence of young planets. The near-infrared light reflecting off the dust ring is about 1,000 times fainter than the illuminating central star. Astronomers used a coronagraphic camera on Hubble's Near Infrared Camera and Multi-Object Spectrometer (NICMOS), specifically designed to enable observations of very faint and low surface brightness objects in the close proximity to bright stars. Even with the coronagraph, the glare from HR 4796A overwhelms the much-fainter ring at distances less than about 4 billion miles (inside the blacked-out circle, centered on the star). Hubble's crisp view was able to resolve the ring, seen at lower resolution at longer wavelengths, in ground-based thermal infrared images, as a disk with some degree of central clearing. The ring has an angular radius of 1.05 arc seconds, equivalent to the apparent size of a dime seen more than 4 miles away. Unlike the extensive disks of dust seen around other young stars, the HR 4796A dust ring, 6.5 billion miles from the star, is tightly confined within a relatively narrow zone less than 17 Astronomical Units wide. An Astronomical Unit is the distance from the Earth to the Sun). For comparison, the ring width is approximately equal to the distance separating the orbits of Mars and Uranus in our own Solar System. All dust rings, whether around stars or planets, can only stay intact by some mechanism confining the dust, likely the gravitational tug of unseen planets. The image was taken on March 15, 1998, centered at a near infrared wavelength of 1.1 microns. The false-color corresponds to the ring's brightness (yellow is bright, purple is faint). The ring, which is undoubtedly circular, appears elliptical since

WPS criterion proposition based on experimental data base interpretation

International Nuclear Information System (INIS)

Chapuliot, S.; Izard, J.P.; Moinereau, D.; Marie, S.

2011-01-01

This article gives the background and the methodology developed to define a K J based criterion for brittle fracture of Reactor Pressure Vessel (RPV) submitted to Pressurized Thermal Shock (PTS), and taking into account Warm Pre Stressing effect (WPS). The first step of this methodology is the constitution of an experimental data base. This work was performed through bibliography and partnerships, and allows merging experimental results dealing with: -) Various ferritic steels; -) Various material states (as received, thermally aged, irradiated...); -) Various mode of fracture (cleavage, inter-granular, mixed mode); -) Various specimen geometry and size (CT, SENB, mock-ups); -) Various thermo-mechanical transients. Based on this experimental data base, a simple K J based limit is proposed and compared to experimental results. Parametric studies are performed in order to define the main parameters of the problem. Finally, a simple proposition based on a detailed analysis of tests results is performed. This proposition giving satisfactory results in every cases, it constitutes a good candidate for integration in French RSE-M code for in service assessment. (authors)

Synthesis of 1,3-bis(organylchalcogeno)propanes and 1,2-dichalcogenolanes having different chalcogen atoms in the molecule; Sintez 1,3-bis(organilkhal'kogeno)propanov i 1,2-dikhal'kogenolanov s razlichnymi atomami khal'kogenov v molekule

Energy Technology Data Exchange (ETDEWEB)

Elaev, A V; Grabel' nykh, V A; Russavskaya, N V; Klyba, L V; Zhanchipova, E R; Levanova, E P; Sukhomazova, Eh N; Albanov, A I; Mamaseva, T V; Korchevin, N A [SO RAN, Irkutskij Inst. Khimii im. A.E. Favorskogo, Irkutsk (Russian Federation)

2007-01-15

Oligomeric trimethylene dichalcogenides and the corresponding 1,2-dichalcogenolanes having both similar and different chalcogen atoms in the molecule were synthesized by reactions of 1-bromo-3-chloropropanes with two elemental chalcogens (S, Se; S, Te; Se, Te) activated by the system hydrazine hydrate-alkali. Reductive cleavage of the oligomeric products in the system hydrazine hydrate-alkali, followed by alkylation with methyl io or ethyl bromide gave 1,3-bis(alkylchalcogeno)propanes. The latter were also obtained from the corresponding dialkyl dichalcogenides and 1-bromo-3-chloropropane in the alkaline reducing systemRuss.

Set-Based Discrete Particle Swarm Optimization Based on Decomposition for Permutation-Based Multiobjective Combinatorial Optimization Problems.

Science.gov (United States)

Yu, Xue; Chen, Wei-Neng; Gu, Tianlong; Zhang, Huaxiang; Yuan, Huaqiang; Kwong, Sam; Zhang, Jun

2017-08-07

This paper studies a specific class of multiobjective combinatorial optimization problems (MOCOPs), namely the permutation-based MOCOPs. Many commonly seen MOCOPs, e.g., multiobjective traveling salesman problem (MOTSP), multiobjective project scheduling problem (MOPSP), belong to this problem class and they can be very different. However, as the permutation-based MOCOPs share the inherent similarity that the structure of their search space is usually in the shape of a permutation tree, this paper proposes a generic multiobjective set-based particle swarm optimization methodology based on decomposition, termed MS-PSO/D. In order to coordinate with the property of permutation-based MOCOPs, MS-PSO/D utilizes an element-based representation and a constructive approach. Through this, feasible solutions under constraints can be generated step by step following the permutation-tree-shaped structure. And problem-related heuristic information is introduced in the constructive approach for efficiency. In order to address the multiobjective optimization issues, the decomposition strategy is employed, in which the problem is converted into multiple single-objective subproblems according to a set of weight vectors. Besides, a flexible mechanism for diversity control is provided in MS-PSO/D. Extensive experiments have been conducted to study MS-PSO/D on two permutation-based MOCOPs, namely the MOTSP and the MOPSP. Experimental results validate that the proposed methodology is promising.

Evidence-based guidelines, time-based health outcomes, and the Matthew effect

NARCIS (Netherlands)

M.L.E. Essink-Bot (Marie-Louise); M.E. Kruijshaar (Michelle); J.J.M. Barendregt (Jan); L.G.A. Bonneux (Luc)

2007-01-01

textabstractBackground: Cardiovascular risk management guidelines are 'risk based'; health economists' practice is 'time based'. The 'medical' risk-based allocation model maximises numbers of deaths prevented by targeting subjects at high risk, for example, elderly and smokers. The time-based model

Evidence-based guidelines, time-based health outcomes, and the Matthew effect

NARCIS (Netherlands)

Essink-Bot, Marie-Louise; Kruijshaar, Michelle E.; Barendregt, Jan J.; Bonneux, Luc G. A.

2007-01-01

BACKGROUND: Cardiovascular risk management guidelines are 'risk based'; health economists' practice is 'time based'. The 'medical' risk-based allocation model maximises numbers of deaths prevented by targeting subjects at high risk, for example, elderly and smokers. The time-based model maximises

0-6621 : developing a mixture-based specification for flexible base.

Science.gov (United States)

2012-08-01

The Texas Department of Transportation : (TxDOT) currently utilizes Item 247, Flexible : Base, to specify a foundation course of flexible : base utilized in a pavement. Base materials are : not allowed to be used by the contractors until : the ...

Acids and bases solvent effects on acid-base strenght

CERN Document Server

Cox, Brian G

2013-01-01

Acids and bases are ubiquitous in chemistry. Our understanding of them, however, is dominated by their behaviour in water. Transfer to non-aqueous solvents leads to profound changes in acid-base strengths and to the rates and equilibria of many processes: for example, synthetic reactions involving acids, bases and nucleophiles; isolation of pharmaceutical actives through salt formation; formation of zwitter- ions in amino acids; and chromatographic separation of substrates. This book seeks to enhance our understanding of acids and bases by reviewing and analysing their behaviour in non-aqueous solvents. The behaviour is related where possible to that in water, but correlations and contrasts between solvents are also presented.

Characteristic-Based, Task-Based, and Results-Based: Three Value Systems for Assessing Professionally Produced Technical Communication Products.

Science.gov (United States)

Carliner, Saul

2003-01-01

Notes that technical communicators have developed different methodologies for evaluating the effectiveness of their work, such as editing, usability testing, and determining the value added. Explains that at least three broad value systems underlie the assessment practices: characteristic-based, task-based, and results-based. Concludes that the…

Designing Android Based Augmented Reality Location-Based Service Application

Directory of Open Access Journals (Sweden)

Alim Hardiansyah

2018-01-01

Full Text Available Android is an operating system for Linux based smartphone. Android provides an open platform for the developers to create their own application. The most developed and used application now is location based application. This application gives personalization service for mobile device user and is customized to their location. Location based service also gives an opportunity for the developers to develop and increase the value of service. One of the technologies that could be combined with location based application is augmented reality. Augmented reality combines the virtual world with the real one. By the assistance of augmented reality, our surrounding environment could interact in digital form. Information of objects and environment surround us could be added to the augmented reality system and presented. Based on the background, the writers tried to implement those technologies on now rapidly developing android application as a final project to achieve bachelor degree in Department of Informatics Engineering, Faculty of Information Technology and Visual Communication, Al Kamal Science and Technology Institute. This application could be functioned to locate school by using location based service technology with the assistance of navigational applications such as waze and google maps, in form of live direction process through the smartphone

Selective Distance-Based K+ Quantification on Paper-Based Microfluidics.

Science.gov (United States)

Gerold, Chase T; Bakker, Eric; Henry, Charles S

2018-04-03

In this study, paper-based microfluidic devices (μPADs) capable of K + quantification in aqueous samples, as well as in human serum, using both colorimetric and distance-based methods are described. A lipophilic phase containing potassium ionophore I (valinomycin) was utilized to achieve highly selective quantification of K + in the presence of Na + , Li + , and Mg 2+ ions. Successful addition of a suspended lipophilic phase to a wax printed paper-based device is described and offers a solution to current approaches that rely on organic solvents, which damage wax barriers. The approach provides an avenue for future alkali/alkaline quantification utilizing μPADs. Colorimetric spot tests allowed for K + quantification from 0.1-5.0 mM using only 3.00 μL of sample solution. Selective distance-based quantification required small sample volumes (6.00 μL) and gave responses sensitive enough to distinguish between 1.0 and 2.5 mM of sample K + . μPADs using distance-based methods were also capable of differentiating between 4.3 and 6.9 mM K + in human serum samples. Distance-based methods required no digital analysis, electronic hardware, or pumps; any steps required for quantification could be carried out using the naked eye.

VectorBase

Data.gov (United States)

U.S. Department of Health & Human Services — VectorBase is a Bioinformatics Resource Center for invertebrate vectors. It is one of four Bioinformatics Resource Centers funded by NIAID to provide web-based...

Owner-Based Role-Based Access Control OB-RBAC

NARCIS (Netherlands)

Saffarian, M.; Sadighi, Babak

Administration of an access control model deals with the question of who is authorized to update policies defined on the basis of that model. One of the models whose administration has absorbed relatively large research is the Role-Based Access Control (RBAC) model. All the existing role-based

Characteristics Data Base: Programmer's guide to the LWR Quantities Data Base

International Nuclear Information System (INIS)

Jones, K.E.; Moore, R.S.

1990-08-01

The LWR Quantities Data Base is a menu-driven PC data base developed as part of OCRWM's waste, technical data base on the characteristics of potential repository wastes, which also includes non-LWR spent fuel, high-level and other materials. This programmer's guide completes the documentation for the LWR Quantities Data Base, the user's guide having been published previously. The PC data base itself may be requested from the Oak Ridge National Laboratory, using the order form provided in Volume 1 of publication DOE/RW-0184

Interaction between scene-based and array-based contextual cueing.

Science.gov (United States)

Rosenbaum, Gail M; Jiang, Yuhong V

2013-07-01

Contextual cueing refers to the cueing of spatial attention by repeated spatial context. Previous studies have demonstrated distinctive properties of contextual cueing by background scenes and by an array of search items. Whereas scene-based contextual cueing reflects explicit learning of the scene-target association, array-based contextual cueing is supported primarily by implicit learning. In this study, we investigated the interaction between scene-based and array-based contextual cueing. Participants searched for a target that was predicted by both the background scene and the locations of distractor items. We tested three possible patterns of interaction: (1) The scene and the array could be learned independently, in which case cueing should be expressed even when only one cue was preserved; (2) the scene and array could be learned jointly, in which case cueing should occur only when both cues were preserved; (3) overshadowing might occur, in which case learning of the stronger cue should preclude learning of the weaker cue. In several experiments, we manipulated the nature of the contextual cues present during training and testing. We also tested explicit awareness of scenes, scene-target associations, and arrays. The results supported the overshadowing account: Specifically, scene-based contextual cueing precluded array-based contextual cueing when both were predictive of the location of a search target. We suggest that explicit, endogenous cues dominate over implicit cues in guiding spatial attention.

Brain-Based Learning and Standards-Based Elementary Science.

Science.gov (United States)

Konecki, Loretta R.; Schiller, Ellen

This paper explains how brain-based learning has become an area of interest to elementary school science teachers, focusing on the possible relationships between, and implications of, research on brain-based learning to the teaching of science education standards. After describing research on the brain, the paper looks at three implications from…

BEAT: A Web-Based Boolean Expression Fault-Based Test Case Generation Tool

Science.gov (United States)

Chen, T. Y.; Grant, D. D.; Lau, M. F.; Ng, S. P.; Vasa, V. R.

2006-01-01

BEAT is a Web-based system that generates fault-based test cases from Boolean expressions. It is based on the integration of our several fault-based test case selection strategies. The generated test cases are considered to be fault-based, because they are aiming at the detection of particular faults. For example, when the Boolean expression is in…

Rule-Based and Case-Based Reasoning in Housing Prices

OpenAIRE

Gabrielle Gayer; Itzhak Gilboa; Offer Lieberman

2004-01-01

People reason about real-estate prices both in terms of general rules and in terms of analogies to similar cases. We propose to empirically test which mode of reasoning fits the data better. To this end, we develop the statistical techniques required for the estimation of the case-based model. It is hypothesized that case-based reasoning will have relatively more explanatory power in databases of rental apartments, whereas rule-based reasoning will have a relative advantage in sales data. We ...

Object-Based Benefits without Object-Based Representations

OpenAIRE

Alvarez, George Angelo; Fougnie, Daryl; Cormiea, Sarah M

2012-01-01

The organization of visual information into objects strongly influences visual memory: Displays with objects defined by two features (e.g. color, orientation) are easier to remember than displays with twice as many objects defined by one feature (Olson & Jiang, 2002). Existing theories suggest that this ‘object-benefit’ is based on object-based limitations in working memory: because a limited number of objects can be stored, packaging features together so that fewer objects have to be remembe...

An Ontology-Based Tourism Recommender System Based on Spreading Activation Model

Science.gov (United States)

Bahramian, Z.; Abbaspour, R. Ali

2015-12-01

A tourist has time and budget limitations; hence, he needs to select points of interest (POIs) optimally. Since the available information about POIs is overloading, it is difficult for a tourist to select the most appreciate ones considering preferences. In this paper, a new travel recommender system is proposed to overcome information overload problem. A recommender system (RS) evaluates the overwhelming number of POIs and provides personalized recommendations to users based on their preferences. A content-based recommendation system is proposed, which uses the information about the user's preferences and POIs and calculates a degree of similarity between them. It selects POIs, which have highest similarity with the user's preferences. The proposed content-based recommender system is enhanced using the ontological information about tourism domain to represent both the user profile and the recommendable POIs. The proposed ontology-based recommendation process is performed in three steps including: ontology-based content analyzer, ontology-based profile learner, and ontology-based filtering component. User's feedback adapts the user's preferences using Spreading Activation (SA) strategy. It shows the proposed recommender system is effective and improves the overall performance of the traditional content-based recommender systems.

AN ONTOLOGY-BASED TOURISM RECOMMENDER SYSTEM BASED ON SPREADING ACTIVATION MODEL

Directory of Open Access Journals (Sweden)

Z. Bahramian

2015-12-01

Full Text Available A tourist has time and budget limitations; hence, he needs to select points of interest (POIs optimally. Since the available information about POIs is overloading, it is difficult for a tourist to select the most appreciate ones considering preferences. In this paper, a new travel recommender system is proposed to overcome information overload problem. A recommender system (RS evaluates the overwhelming number of POIs and provides personalized recommendations to users based on their preferences. A content-based recommendation system is proposed, which uses the information about the user’s preferences and POIs and calculates a degree of similarity between them. It selects POIs, which have highest similarity with the user’s preferences. The proposed content-based recommender system is enhanced using the ontological information about tourism domain to represent both the user profile and the recommendable POIs. The proposed ontology-based recommendation process is performed in three steps including: ontology-based content analyzer, ontology-based profile learner, and ontology-based filtering component. User’s feedback adapts the user’s preferences using Spreading Activation (SA strategy. It shows the proposed recommender system is effective and improves the overall performance of the traditional content-based recommender systems.

Contests versus Norms: Implications of Contest-Based and Norm-Based Intervention Techniques.

Science.gov (United States)

Bergquist, Magnus; Nilsson, Andreas; Hansla, André

2017-01-01

Interventions using either contests or norms can promote environmental behavioral change. Yet research on the implications of contest-based and norm-based interventions is lacking. Based on Goal-framing theory, we suggest that a contest-based intervention frames a gain goal promoting intensive but instrumental behavioral engagement. In contrast, the norm-based intervention was expected to frame a normative goal activating normative obligations for targeted and non-targeted behavior and motivation to engage in pro-environmental behaviors in the future. In two studies participants ( n = 347) were randomly assigned to either a contest- or a norm-based intervention technique. Participants in the contest showed more intensive engagement in both studies. Participants in the norm-based intervention tended to report higher intentions for future energy conservation (Study 1) and higher personal norms for non-targeted pro-environmental behaviors (Study 2). These findings suggest that contest-based intervention technique frames a gain goal, while norm-based intervention frames a normative goal.

Contests versus Norms: Implications of Contest-Based and Norm-Based Intervention Techniques

Directory of Open Access Journals (Sweden)

Magnus Bergquist

2017-11-01

Full Text Available Interventions using either contests or norms can promote environmental behavioral change. Yet research on the implications of contest-based and norm-based interventions is lacking. Based on Goal-framing theory, we suggest that a contest-based intervention frames a gain goal promoting intensive but instrumental behavioral engagement. In contrast, the norm-based intervention was expected to frame a normative goal activating normative obligations for targeted and non-targeted behavior and motivation to engage in pro-environmental behaviors in the future. In two studies participants (n = 347 were randomly assigned to either a contest- or a norm-based intervention technique. Participants in the contest showed more intensive engagement in both studies. Participants in the norm-based intervention tended to report higher intentions for future energy conservation (Study 1 and higher personal norms for non-targeted pro-environmental behaviors (Study 2. These findings suggest that contest-based intervention technique frames a gain goal, while norm-based intervention frames a normative goal.

Embracing a competency-based specialty curriculum for community-based nursing roles.

Science.gov (United States)

Levin, Pamela F; Swider, Susan M; Breakwell, Susan; Cowell, Julia M; Reising, Virginia

2013-01-01

The Quad Council competencies for public health nursing (PHN) provide guidance in developing curricula at both the generalist and specialist level. However, these competencies are based on nursing roles in traditional public health agencies and community/public health is defined more broadly than official agency practice. The question arises as to whether community-based specialties require largely the same knowledge and skill set as PHN. The purpose of the competency cross-mapping project reported here was to (a) assess the intersection of the Quad Council competencies with four community-based specialties and (b) ensure the appropriateness of a Quad Council-based curriculum to prepare graduates across these four specialties (home health, occupational health, environmental health, and school nursing). This article details the multistep cross-mapping process, including validation with practice leaders. Results indicate strong alignment of community-based specialty competencies with Quad Council competencies. Community-based specialty-specific content that did not align well is identified, along with examples of didactic and clinical strategies to address gaps. This work indicates that a Quad Council-based curriculum is appropriate to prepare graduates in community-based specialties when attention to the specialty-specific competencies in the clinical setting is included. This work guides the development of a doctorate of nursing practice curriculum in PHN, encompassing the four additional community-based specialties. © 2013 Wiley Periodicals, Inc.

Foundry based approach for InP based PIC development

NARCIS (Netherlands)

Smit, M.K.

2014-01-01

Europe is making significant investments in development of generic photonic foundry platform infrastructures for InP-based and Silicon Photonic ICs. Here we present the present status for the InP-based JePPIX platform.

Managing the Gap between Curriculum Based and Problem Based Learning

DEFF Research Database (Denmark)

Bygholm, Ann; Buus, Lillian

2009-01-01

/or but rather both/and. In this paper we describe an approach to design and delivery of online courses in computer science which on the one hand is based on a specified curriculum and on the other hand gives room for different learning strategies, problem based learning being one of them. We discuss......Traditionally there has been a clear distinction between curriculum based and problem based approaches to accomplish learning. Preferred approaches depend of course on conviction, culture, traditions and also on the specific learning situation. We will argue that it is not a question of either...

Groebner Bases Based Verification Solution for SystemVerilog Concurrent Assertions

Directory of Open Access Journals (Sweden)

Ning Zhou

2014-01-01

of polynomial ring algebra to perform SystemVerilog assertion verification over digital circuit systems. This method is based on Groebner bases theory and sequential properties checking. We define a constrained subset of SVAs so that an efficient polynomial modeling mechanism for both circuit descriptions and assertions can be applied. We present an algorithm framework based on the algebraic representations using Groebner bases for concurrent SVAs checking. Case studies show that computer algebra can provide canonical symbolic representations for both assertions and circuit designs and can act as a novel solver engine from the viewpoint of symbolic computation.

A Computer-Based Simulation of an Acid-Base Titration

Science.gov (United States)

Boblick, John M.

1971-01-01

Reviews the advantages of computer simulated environments for experiments, referring in particular to acid-base titrations. Includes pre-lab instructions and a sample computer printout of a student's use of an acid-base simulation. Ten references. (PR)

Research on the comparison of performance-based concept and force-based concept

Science.gov (United States)

Wu, Zeyu; Wang, Dongwei

2011-03-01

There are two ideologies about structure design: force-based concept and performance-based concept. Generally, if the structure operates during elastic stage, the two philosophies usually attain the same results. But beyond that stage, the shortage of force-based method is exposed, and the merit of performance-based is displayed. Pros and cons of each strategy are listed herein, and then which structure is best suitable to each method analyzed. At last, a real structure is evaluated by adaptive pushover method to verify that performance-based method is better than force-based method.

USEMS & GLASS: investigator-driven frontier research in earthquake physics. Ground-breaking research in Europe enhances outreach to the general public

Science.gov (United States)

Mariano, S.; di Toro, G.; Collettini, C.; Usems Team; Glass Team

2011-12-01

USEMS and GLASS are two projects financed by the European Research Council (ERC) as part of the ERC starting grants scheme within the FP7 framework. The rationale behind the funding scheme is to support some of the most promising scientific endeavours in Europe that are being led by young researchers, and to emphasize the excellence of individual ideas rather than specific research areas; in other words, to promote bottom-up frontier research. The general benefits of this rationale are evident in the two ongoing projects that deal with earthquake physics, as these projects are increasingly recognized in their scientific community. We can say that putting excellence at the heart of European Research strongly contributes to the construction of a European knowledge-based society. From a researcher point-of-view one of the most challenging aspects of these projects is to approach and convey the results of the projects to a general public, contributing to the construction of knowledge-based society. Luckily, media interest and the availability of a number of new communication tools facilitate the outreach of scientific achievements. The largest earthquakes during the last ten years (e.g. Sumatra 2004 and Japan 2011) have received widespread attention in the media world (TV, W.W.W., Newspaper and so on) for months, and successful research projects such as those above also become media protagonists, gaining their space in the media bullring. The USEMS principal investigator and his team have participated in several dissemination events in the Mass Media, such as interviews wit Italian and French TV national broadcasts (RAI Due TG2, RAI Uno Unomattina, Rai Tre Geo & Geo, FRANCE 2); interviews in scientific journals: SCIENCE (Sept. 2010), newspapers and web (Corriere della Sera, Il Gazzettino, Il Messagero, La Stampa, Libero, Il Mattino, Yahoo, ANSA, AdnKronos and AGI); radio (RadioRai Uno, RadioRai Tre Scienza); documentary "Die Eroberung der Alpen" produced by Tangram

Priority-Based Hierarchical Operational Management for Multiagent-Based Microgrids

Directory of Open Access Journals (Sweden)

Takumi Kato

2014-03-01

Full Text Available Electricity consumption in the world is constantly increasing, making our lives become more and more dependent on electricity. There are several new paradigms proposed in the field of power grids. In Japan, especially after the Great East Japan Earthquake in March 2011, the new power grid paradigms are expected to be more resilient to survive several difficulties during disasters. In this paper, we focus on microgrids and propose priority-based hierarchical operational management for multiagent-based microgrids. The proposed management is a new multiagent-based load shedding scheme and multiagent-based hierarchical architecture to realize such resilient microgrids. We developed a prototype system and performed an evaluation of the proposed management using the developed system. The result of the evaluation shows the effectiveness of our proposal in power shortage situations, such as disasters.

Feature-based attention is functionally distinct from relation-based attention: The double dissociation between color-based capture and color-relation-based capture of attention.

Science.gov (United States)

Du, Feng; Jiao, Jun

2016-04-01

The present study used a spatial blink task and a cuing task to examine the boundary between feature-based capture and relation-based capture. Feature-based capture occurs when distractors match the target feature such as target color. The occurrence of relation-based capture is contingent upon the feature relation between target and distractor (e.g., color relation). The results show that color distractors that match the target-nontarget color relation do not consistently capture attention when they appear outside of the attentional window, but distractors appearing outside the attentional window that match the target color consistently capture attention. In contrast, color distractors that best match the target-nontarget color relation but not the target color, are more likely to capture attention when they appear within the attentional window. Consistently, color cues that match the target-nontarget color relation produce a cuing effect when they appear within the attentional window, while target-color matched cues do not. Such a double dissociation between color-based capture and color-relation-based capture indicates functionally distinct mechanisms for these 2 types of attentional selection. This also indicates that the spatial blink task and the uninformative cuing task are measuring distinctive aspects of involuntary attention. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Skull base tumours

Energy Technology Data Exchange (ETDEWEB)

Borges, Alexandra [Instituto Portugues de Oncologia Francisco Gentil, Servico de Radiologia, Rua Professor Lima Basto, 1093 Lisboa Codex (Portugal)], E-mail: borgesalexandra@clix.pt

2008-06-15

With the advances of cross-sectional imaging radiologists gained an increasing responsibility in the management of patients with skull base pathology. As this anatomic area is hidden to clinical exam, surgeons and radiation oncologists have to rely on imaging studies to plan the most adequate treatment. To fulfil these endeavour radiologists need to be knowledgeable about skull base anatomy, about the main treatment options available, their indications and contra-indications and needs to be aware of the wide gamut of pathologies seen in this anatomic region. This article will provide a radiologists' friendly approach to the central skull base and will review the most common central skull base tumours and tumours intrinsic to the bony skull base.

Skull base tumours

International Nuclear Information System (INIS)

Borges, Alexandra

2008-01-01

With the advances of cross-sectional imaging radiologists gained an increasing responsibility in the management of patients with skull base pathology. As this anatomic area is hidden to clinical exam, surgeons and radiation oncologists have to rely on imaging studies to plan the most adequate treatment. To fulfil these endeavour radiologists need to be knowledgeable about skull base anatomy, about the main treatment options available, their indications and contra-indications and needs to be aware of the wide gamut of pathologies seen in this anatomic region. This article will provide a radiologists' friendly approach to the central skull base and will review the most common central skull base tumours and tumours intrinsic to the bony skull base

State-based versus reward-based motivation in younger and older adults.

Science.gov (United States)

Worthy, Darrell A; Cooper, Jessica A; Byrne, Kaileigh A; Gorlick, Marissa A; Maddox, W Todd

2014-12-01

Recent decision-making work has focused on a distinction between a habitual, model-free neural system that is motivated toward actions that lead directly to reward and a more computationally demanding goal-directed, model-based system that is motivated toward actions that improve one's future state. In this article, we examine how aging affects motivation toward reward-based versus state-based decision making. Participants performed tasks in which one type of option provided larger immediate rewards but the alternative type of option led to larger rewards on future trials, or improvements in state. We predicted that older adults would show a reduced preference for choices that led to improvements in state and a greater preference for choices that maximized immediate reward. We also predicted that fits from a hybrid reinforcement-learning model would indicate greater model-based strategy use in younger than in older adults. In line with these predictions, older adults selected the options that maximized reward more often than did younger adults in three of the four tasks, and modeling results suggested reduced model-based strategy use. In the task where older adults showed similar behavior to younger adults, our model-fitting results suggested that this was due to the utilization of a win-stay-lose-shift heuristic rather than a more complex model-based strategy. Additionally, within older adults, we found that model-based strategy use was positively correlated with memory measures from our neuropsychological test battery. We suggest that this shift from state-based to reward-based motivation may be due to age related declines in the neural structures needed for more computationally demanding model-based decision making.

Image based Monument Recognition using Graph based Visual Saliency

DEFF Research Database (Denmark)

Kalliatakis, Grigorios; Triantafyllidis, Georgios

2013-01-01

This article presents an image-based application aiming at simple image classification of well-known monuments in the area of Heraklion, Crete, Greece. This classification takes place by utilizing Graph Based Visual Saliency (GBVS) and employing Scale Invariant Feature Transform (SIFT) or Speeded......, the images have been previously processed according to the Graph Based Visual Saliency model in order to keep either SIFT or SURF features corresponding to the actual monuments while the background “noise” is minimized. The application is then able to classify these images, helping the user to better...

Convergent Filter Bases

Directory of Open Access Journals (Sweden)

Coghetto Roland

2015-09-01

Full Text Available We are inspired by the work of Henri Cartan [16], Bourbaki [10] (TG. I Filtres and Claude Wagschal [34]. We define the base of filter, image filter, convergent filter bases, limit filter and the filter base of tails (fr: filtre des sections.

QuickBase

CERN Document Server

Conner, Nancy

2007-01-01

Ready to put Intuit's QuickBase to work? Our new Missing Manual shows you how to capture, modify, share, and manage data and documents with this web-based data-sharing program quickly and easily. No longer do you have to coordinate your team through a blizzard of emails or play frustrating games of "guess which document is the right one."QuickBase saves your organization time and money, letting you manage and share the information that makes your business tick: sales figures, project timelines, drafts of documents, purchase or work requests--whatever information you need to keep business flowi

Merits of using andalusite-based refractories compared to bauxite-based refractories

OpenAIRE

Nyoka, M.; Brazier, D.; Courtney, T.; Parry, R.A.

2013-01-01

Historically bauxite-based refractories have been used in applications where andalusite-based refractories could work. Bauxite-based refractories were chosen over andalusite-based refractories mainly because of the availability of low-cost Chinese bauxite and also because many furnaces were designed by international companies that cannot easily access high-quality products. Currently, the availability of low-cost bauxite is under threat as a result of high export duties and tariffs as well as...

Swarm-based medicine.

Science.gov (United States)

Putora, Paul Martin; Oldenburg, Jan

2013-09-19

Occasionally, medical decisions have to be taken in the absence of evidence-based guidelines. Other sources can be drawn upon to fill in the gaps, including experience and intuition. Authorities or experts, with their knowledge and experience, may provide further input--known as "eminence-based medicine". Due to the Internet and digital media, interactions among physicians now take place at a higher rate than ever before. With the rising number of interconnected individuals and their communication capabilities, the medical community is obtaining the properties of a swarm. The way individual physicians act depends on other physicians; medical societies act based on their members. Swarm behavior might facilitate the generation and distribution of knowledge as an unconscious process. As such, "swarm-based medicine" may add a further source of information to the classical approaches of evidence- and eminence-based medicine. How to integrate swarm-based medicine into practice is left to the individual physician, but even this decision will be influenced by the swarm.

Touch BASE

CERN Multimedia

Antonella Del Rosso

2015-01-01

In a recent Nature article (see here), the BASE collaboration reported the most precise comparison of the charge-to-mass ratio of the proton to its antimatter equivalent, the antiproton. This result is just the beginning and many more challenges lie ahead.   CERN's AD Hall, where the BASE experiment is set-up. The Baryon Antibaryon Symmetry Experiment (BASE) was approved in June 2013 and was ready to take data in August 2014. During these 14 months, the BASE collaboration worked hard to set up its four cryogenic Penning traps, which are the heart of the whole experiment. As their name indicates, these magnetic devices are used to trap antiparticles – antiprotons coming from the Antiproton Decelerator – and particles of matter – negative hydrogen ions produced in the system by interaction with a degrader that slows the antiprotons down, allowing scientists to perform their measurements. “We had very little time to set up the wh...

Evaluation of radiosurgery techniques–Cone-based linac radiosurgery vs tomotherapy-based radiosurgery

International Nuclear Information System (INIS)

Yip, Ho Yin; Mui, Wing Lun A.; Lee, Joseph W.Y.; Fung, Winky Wing Ki; Chan, Jocelyn M.T.; Chiu, G.; Law, Maria Y.Y.

2013-01-01

Performances of radiosurgery of intracranial lesions between cone-based Linac system and Tomotherapy-based system were compared in terms of dosimetry and time. Twelve patients with single intracranial lesion treated with cone-based Linac radiosurgery system from 2005 to 2009 were replanned for Tomotherapy-based radiosurgery treatment. The conformity index, homogeneity index (HI), and gradient score index (GSI) of each case was calculated. The Wilcoxon matched-pair test was used to compare the 3 indices between both systems. The cases with regular target (n = 6) and those with irregular target (n = 6) were further analyzed separately. The estimated treatment time between both systems was also compared. Significant differences were found in HI (p = 0.05) and in GSI (p = 0.03) for the whole group. Cone-based radiosurgery was better in GSI whereas Tomotherapy-based radiosurgery was better in HI. Cone-based radiosurgery was better in conformity index (p = 0.03) and GSI (p = 0.03) for regular targets, whereas Tomotherapy-based radiosurgery system performed significantly better in HI (p = 0.03) for irregular targets. The estimated total treatment time for Tomotherapy-based radiosurgery ranged from 24 minutes to 35 minutes, including 15 minutes of pretreatment megavoltage computed tomography (MVCT) and image registration, whereas that for cone-based radiosurgery ranged from 15 minutes for 1 isocenter to 75 minutes for 5 isocenters. As a rule of thumb, Tomotherapy-based radiosurgery system should be the first-line treatment for irregular lesions because of better dose homogeneity and shorter treatment time. Cone-based Linac radiosurgery system should be the treatment of choice for regular targets because of the better dose conformity, rapid dose fall-off, and reasonable treatment time

Evaluation of radiosurgery techniques–Cone-based linac radiosurgery vs tomotherapy-based radiosurgery

Energy Technology Data Exchange (ETDEWEB)

Yip, Ho Yin, E-mail: hoyinyip@yahoo.com.hk [Department of Radiotherapy, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong (China); Mui, Wing Lun A.; Lee, Joseph W.Y.; Fung, Winky Wing Ki; Chan, Jocelyn M.T.; Chiu, G. [Department of Radiotherapy, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong (China); Law, Maria Y.Y. [Medical Physics and Research Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong (China)

2013-07-01

Performances of radiosurgery of intracranial lesions between cone-based Linac system and Tomotherapy-based system were compared in terms of dosimetry and time. Twelve patients with single intracranial lesion treated with cone-based Linac radiosurgery system from 2005 to 2009 were replanned for Tomotherapy-based radiosurgery treatment. The conformity index, homogeneity index (HI), and gradient score index (GSI) of each case was calculated. The Wilcoxon matched-pair test was used to compare the 3 indices between both systems. The cases with regular target (n = 6) and those with irregular target (n = 6) were further analyzed separately. The estimated treatment time between both systems was also compared. Significant differences were found in HI (p = 0.05) and in GSI (p = 0.03) for the whole group. Cone-based radiosurgery was better in GSI whereas Tomotherapy-based radiosurgery was better in HI. Cone-based radiosurgery was better in conformity index (p = 0.03) and GSI (p = 0.03) for regular targets, whereas Tomotherapy-based radiosurgery system performed significantly better in HI (p = 0.03) for irregular targets. The estimated total treatment time for Tomotherapy-based radiosurgery ranged from 24 minutes to 35 minutes, including 15 minutes of pretreatment megavoltage computed tomography (MVCT) and image registration, whereas that for cone-based radiosurgery ranged from 15 minutes for 1 isocenter to 75 minutes for 5 isocenters. As a rule of thumb, Tomotherapy-based radiosurgery system should be the first-line treatment for irregular lesions because of better dose homogeneity and shorter treatment time. Cone-based Linac radiosurgery system should be the treatment of choice for regular targets because of the better dose conformity, rapid dose fall-off, and reasonable treatment time.

Nasal base narrowing: the combined alar base excision technique.

Science.gov (United States)

Foda, Hossam M T

2007-01-01

To evaluate the role of the combined alar base excision technique in narrowing the nasal base and correcting excessive alar flare. The study included 60 cases presenting with a wide nasal base and excessive alar flaring. The surgical procedure combined an external alar wedge resection with an internal vestibular floor excision. All cases were followed up for a mean of 32 (range, 12-144) months. Nasal tip modification and correction of any preexisting caudal septal deformities were always completed before the nasal base narrowing. The mean width of the external alar wedge excised was 7.2 (range, 4-11) mm, whereas the mean width of the sill excision was 3.1 (range, 2-7) mm. Completing the internal excision first resulted in a more conservative external resection, thus avoiding any blunting of the alar-facial crease. No cases of postoperative bleeding, infection, or keloid formation were encountered, and the external alar wedge excision healed with an inconspicuous scar that was well hidden in the depth of the alar-facial crease. Finally, the risk of notching of the alar rim, which can occur at the junction of the external and internal excisions, was significantly reduced by adopting a 2-layered closure of the vestibular floor (P = .01). The combined alar base excision resulted in effective narrowing of the nasal base with elimination of excessive alar flare. Commonly feared complications, such as blunting of the alar-facial crease or notching of the alar rim, were avoided by using simple modifications in the technique of excision and closure.

Developing effective web-based regional anesthesia education: a randomized study evaluating case-based versus non-case-based module design.

Science.gov (United States)

Kopp, Sandra L; Smith, Hugh M

2011-01-01

Little is known about the use of Web-based education in regional anesthesia training. Benefits of Web-based education include the ability to standardize learning material quality and content, build appropriate learning progressions, use interactive multimedia technologies, and individualize delivery of course materials. The goals of this investigation were (1) to determine whether module design influences regional anesthesia knowledge acquisition, (2) to characterize learner preference patterns among anesthesia residents, and (3) to determine whether learner preferences play a role in knowledge acquisition. Direct comparison of knowledge assessments, learning styles, and learner preferences will be made between an interactive case-based and a traditional textbook-style module design. Forty-three Mayo Clinic anesthesiology residents completed 2 online modules, a knowledge pretest, posttest, an Index of Learning Styles assessment, and a participant satisfaction survey. Interscalene and lumbar plexus regional techniques were selected as the learning content for 4 Web modules constructed using the Blackboard Vista coursework application. One traditional textbook-style module and 1 interactive case-based module were designed for each of the interscalene and lumbar plexus techniques. Participants scored higher on the postmodule knowledge assessment for both of the interscalene and lumbar plexus modules. Postmodule knowledge performance scores were independent of both module design (interactive case-based versus traditional textbook style) and learning style preferences. However, nearly all participants reported a preference for Web-based learning and believe that it should be used in anesthesia resident education. Participants did not feel that Web-base learning should replace the current lecture-based curriculum. All residents scored higher on the postmodule knowledge assessment, but this improvement was independent of the module design and individual learning styles

Mindfulness-based and acceptance-based interventions in sport and performance contexts.

Science.gov (United States)

Gardner, Frank L; Moore, Zella E

2017-08-01

Since mindfulness-based and acceptance-based practice models were first conceptualized and applied in sport in an attempt to enhance performance and overall well-being of athletes and performers, these state-of-the-art theoretical and practice models have substantially broadened our knowledge base and have been successfully incorporated into sport and performance practice domains worldwide. Evolving from a sound empirical foundation, mindfulness-based and acceptance-based models in sport psychology have accumulated a strong basic and applied empirical foundation. In the nearly 20 years since their incorporation in the context of sport, empirical findings have demonstrated efficacious outcomes associated with performance and personal well-being, as well as supported their theorized mechanisms of change. Particularly as sport and performance environments increasingly call upon practitioners to provide more comprehensive care to clientele, including a range of care from performance enhancement and maintenance, to general personal well-being, to subclinical and clinical issues, mindfulness-based and acceptance-based practitioners have the tools to offer robust, empirically informed interventions that can enhance skills and quality of life, and/or ameliorate personal struggles. Copyright © 2017 Elsevier Ltd. All rights reserved.

VO2-based radiative thermal transistor with a semi-transparent base

Science.gov (United States)

Prod'homme, Hugo; Ordonez-Miranda, Jose; Ezzahri, Younès; Drévillon, Jérémie; Joulain, Karl

2018-05-01

We study a radiative thermal transistor analogous to an electronic one made of a VO2 base placed between two silica semi-infinite plates playing the roles of the transistor collector and emitter. The fact that VO2 exhibits an insulator to metal transition is exploited to modulate and/or amplify heat fluxes between the emitter and the collector, by applying a thermal current on the VO2 base. We extend the work of precedent studies considering the case where the base can be semi-transparent so that heat can be exchanged directly between the collector and the emitter. Both near and far field cases are considered leading to 4 typical regimes resulting from the fact that the emitter-base and base-collector separation distances can be larger or smaller than the thermal wavelength for a VO2 layer opaque or semi-transparent. Thermal currents variations with the base temperatures are calculated and analyzed. It is found that the transistor can operate in an amplification mode as already stated in [1] or in a switching mode as seen in [2]. An optimum configuration for the base thickness and separation distance maximizing the thermal transistor modulation factor is found.

Facilitators' perceptions of problem-based learning and community-based education

Directory of Open Access Journals (Sweden)

Annali E Fichardt

2000-10-01

Full Text Available In 1997 the School for Nursing, University of the Orange Free State, changed from the traditional lecture method of teaching to problem-based learning and from a curative to a community-based approach. Lecturers from a traditional environment became facilitators and new skills such as listening, dialogue, negotiation, counselling and problemsolving were expected from them. Besides the role change, the environment changed from a structural classroom to an unstructured community. The aim of this research was to determine the perceptions and experiences of facilitators in problem-based learning and community-base education. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

Frame-based safety analysis approach for decision-based errors

International Nuclear Information System (INIS)

Fan, Chin-Feng; Yihb, Swu

1997-01-01

A frame-based approach is proposed to analyze decision-based errors made by automatic controllers or human operators due to erroneous reference frames. An integrated framework, Two Frame Model (TFM), is first proposed to model the dynamic interaction between the physical process and the decision-making process. Two important issues, consistency and competing processes, are raised. Consistency between the physical and logic frames makes a TFM-based system work properly. Loss of consistency refers to the failure mode that the logic frame does not accurately reflect the state of the controlled processes. Once such failure occurs, hazards may arise. Among potential hazards, the competing effect between the controller and the controlled process is the most severe one, which may jeopardize a defense-in-depth design. When the logic and physical frames are inconsistent, conventional safety analysis techniques are inadequate. We propose Frame-based Fault Tree; Analysis (FFTA) and Frame-based Event Tree Analysis (FETA) under TFM to deduce the context for decision errors and to separately generate the evolution of the logical frame as opposed to that of the physical frame. This multi-dimensional analysis approach, different from the conventional correctness-centred approach, provides a panoramic view in scenario generation. Case studies using the proposed techniques are also given to demonstrate their usage and feasibility

From conventional software based systems to knowledge based systems

International Nuclear Information System (INIS)

Bologna, S.

1995-01-01

Even if todays nuclear power plants have a very good safety record, there is a continuous search for still improving safety. One direction of this effort address operational safety, trying to improve the handling of disturbances and accidents partly by further automation, partly by creating a better control room environment, providing the operator with intelligent support systems to help in the decision making process. Introduction of intelligent computerised operator support systems has proved to be an efficient way of improving the operators performance. A number of systems have been developed worldwide, assisting in tasks like process fault detection and diagnosis, selection and implementation of proper remedial actions. Unfortunately, the use of Knowledge Based Systems (KBSs), introduces a new dimension to the problem of the licensing process. KBSs, despite the different technology employed, are still nothing more than a computer program. Unfortunately, quite a few people building knowledge based systems seem to ignore the many good programming practices that have evolved over the years for producing traditional computer programs. In this paper the author will try to point out similarities and differences between conventional software based systems, and knowledge based systems, introducing also the concept of model based reasoning. (orig.) (25 refs., 2 figs.)

Case-based reasoning

CERN Document Server

Kolodner, Janet

1993-01-01

Case-based reasoning is one of the fastest growing areas in the field of knowledge-based systems and this book, authored by a leader in the field, is the first comprehensive text on the subject. Case-based reasoning systems are systems that store information about situations in their memory. As new problems arise, similar situations are searched out to help solve these problems. Problems are understood and inferences are made by finding the closest cases in memory, comparing and contrasting the problem with those cases, making inferences based on those comparisons, and asking questions whe

Lotus Base

DEFF Research Database (Denmark)

Mun, Terry; Bachmann, Asger; Gupta, Vikas

2016-01-01

exploration of Lotus genomic and transcriptomic data. Equally important are user-friendly in-browser tools designed for data visualization and interpretation. Here, we present Lotus Base, which opens to the research community a large, established LORE1 insertion mutant population containing an excess of 120...... such data, allowing users to construct, visualize, and annotate co-expression gene networks. Lotus Base takes advantage of modern advances in browser technology to deliver powerful data interpretation for biologists. Its modular construction and publicly available application programming interface enable...... developers to tap into the wealth of integrated Lotus data. Lotus Base is freely accessible at: https://lotus.au.dk....

Three dimensional pattern recognition using feature-based indexing and rule-based search

Science.gov (United States)

Lee, Jae-Kyu

In flexible automated manufacturing, robots can perform routine operations as well as recover from atypical events, provided that process-relevant information is available to the robot controller. Real time vision is among the most versatile sensing tools, yet the reliability of machine-based scene interpretation can be questionable. The effort described here is focused on the development of machine-based vision methods to support autonomous nuclear fuel manufacturing operations in hot cells. This thesis presents a method to efficiently recognize 3D objects from 2D images based on feature-based indexing. Object recognition is the identification of correspondences between parts of a current scene and stored views of known objects, using chains of segments or indexing vectors. To create indexed object models, characteristic model image features are extracted during preprocessing. Feature vectors representing model object contours are acquired from several points of view around each object and stored. Recognition is the process of matching stored views with features or patterns detected in a test scene. Two sets of algorithms were developed, one for preprocessing and indexed database creation, and one for pattern searching and matching during recognition. At recognition time, those indexing vectors with the highest match probability are retrieved from the model image database, using a nearest neighbor search algorithm. The nearest neighbor search predicts the best possible match candidates. Extended searches are guided by a search strategy that employs knowledge-base (KB) selection criteria. The knowledge-based system simplifies the recognition process and minimizes the number of iterations and memory usage. Novel contributions include the use of a feature-based indexing data structure together with a knowledge base. Both components improve the efficiency of the recognition process by improved structuring of the database of object features and reducing data base size

NSCT BASED LOCAL ENHANCEMENT FOR ACTIVE CONTOUR BASED IMAGE SEGMENTATION APPLICATION

Directory of Open Access Journals (Sweden)

Hiren Mewada

2010-08-01

Full Text Available Because of cross-disciplinary nature, Active Contour modeling techniques have been utilized extensively for the image segmentation. In traditional active contour based segmentation techniques based on level set methods, the energy functions are defined based on the intensity gradient. This makes them highly sensitive to the situation where the underlying image content is characterized by image nonhomogeneities due to illumination and contrast condition. This is the most difficult problem to make them as fully automatic image segmentation techniques. This paper introduces one of the approaches based on image enhancement to this problem. The enhanced image is obtained using NonSubsampled Contourlet Transform, which improves the edges strengths in the direction where the illumination is not proper and then active contour model based on level set technique is utilized to segment the object. Experiment results demonstrate that proposed method can be utilized along with existing active contour model based segmentation method under situation characterized by intensity non-homogeneity to make them fully automatic.

Data base EQDB - data base of the qualified equipment's for NPP

International Nuclear Information System (INIS)

Rovny, K.

2009-01-01

In the contribution, there is presented the project of the data base for qualified equipment's for nuclear power plants. The data base is operated by the 'Certification body which certified the products - the chosen equipment's for nuclear power plants', reg. No. P-028, at VUJE, Inc. Trnava. Data base will serve to the designers, the operators of the nuclear power plants and the workers from Nuclear regulatory authority of the Slovak Republic as a source of information about the state of concrete type equipment's qualification. In the first part of the contribution, there is information about the legislation and technical requirements for equipment's qualification, the way of demonstration and importance of the qualification for the operator. In the next part, there is presented the own structure of data base and the works with own data base regarding the examples of concrete equipment's. The data base will be accessible after the free registration on address WWW.EQDB.sk from 1.5.2009

Evidence-based radiography

International Nuclear Information System (INIS)

Hafslund, Bjorg; Clare, Judith; Graverholt, Birgitte; Wammen Nortvedt, Monica

2008-01-01

Evidence-based practice (EBP) offers the integration of the best research evidence with clinical knowledge and expertise and patient values. EBP is a well known term in health care. This paper discusses the implementation of EBP into radiography and introduces the term evidence-based radiography. Evidence-based radiography is radiography informed and based on the combination of clinical expertise and the best available research-based evidence, patient preferences and resources available. In Norway, EBP in radiography is being debated and radiographers are discussing the challenges of implementing EBP in both academic and clinical practice. This discussion paper explains why EBP needs to be a basis for a radiography curriculum and a part of radiographers' practice. We argue that Norwegian radiographers must increase participation in research and developing practice within their specific radiographic domain

Competency-Based Teaching in Radiology - Implementation and Evaluation of Interactive Workstation-Based Learning to Apply NKLM-Based Content.

Science.gov (United States)

Koestner, Wolfgang; Otten, Wiebke; Kaireit, Till; Wacker, Frank K; Dettmer, Sabine

2017-11-01

Purpose  New teaching formats are required to implement competency-based teaching in radiology teaching. Therefore, we have established and evaluated two practical competency-based radiological courses. Materials and Methods  The courses were held in a multimedia room with 25 computers and a professional DICOM viewer. Students were taught basic image analysis and presented clinical cases with a DICOM viewer under supervision of an instructor using desktop monitoring software. Two courses (elective course and obligatory course) were evaluated by the students (n = 160 and n = 100) and instructors (n = 9) using an anonymized online survey. Results  Courses were evaluated positively by the students and instructors. From the perspective of the students, the courses increased understanding of cross-sectional anatomy (elective/obligatory course: 97 %/95 %) and radiologic findings (97 %/99 %). Furthermore, the course increased the students' interest in radiology (61 %/65 %). The students considered this way of teaching to be relevant to their future occupation (92 % of students in the obligatory course). The higher incidence of teacher-student interaction and the possibility of independent image analysis were rated positively. The majority of instructors did not observe increased distractibility due to the computers (67 %) or notice worse preparation for MC tests (56 %). However, 56 % of instructors reported greater preparation effort. Conclusion  Practical competency-based radiological teaching using a DICOM viewer is a feasible innovative approach with high acceptance among students and instructors. It fosters competency-based learning as proposed by the model curriculum of the German Radiological Society (DRG) and the National Competency-based Catalogue of Learning Objectives for Undergraduate Medical Education (NKLM). Key Points   · Practical competency-based radiological teaching is highly accepted by students and instructors

Cultural and Rhetorical Bases for communicating knowledge in web based communities

DEFF Research Database (Denmark)

Kampf, Constance; Kommers, Piet

2008-01-01

Cultural and Rhetorical Bases for communicating knowledge in web based communities How can we extend learner-centred theories for educational technology to include, for instance, the cultural and rhetorical backgrounds which influence participants in online communities as they engage in knowledge...... via web-based communities the intersection of culture and rhetoric in web-based communication rhetoric and discourse in the process of communicating knowledge via technology heuristics for knowledge communication from teaching in online forums connections between identity and knowledge communication...... This call for papers invites papers focused on theoretical frameworks or empirical research which highlights the cultural and/or rhetorical aspects of communicating knowledge in web based communities. We are looking for work that brings together methods and perspectives across disciplines...

Characteristics Data Base: Programmer's guide to the High-Level Waste Data Base

International Nuclear Information System (INIS)

Jones, K.E.; Salmon, R.

1990-08-01

The High-Level Waste Data Base is a menu-driven PC data base developed as part of OCRWM's technical data base on the characteristics of potential repository wastes, which also includes spent fuel and other materials. This programmer's guide completes the documentation for the High-Level Waste Data Base, the user's guide having been published previously. 3 figs

An Alternative Collaborative Supervision Practice between University-Based Teachers and School-Based Teachers

Science.gov (United States)

Steele, Annfrid R.

2017-01-01

There is an increased focus in teacher education on research-based teaching as a means to develop a more research-based professional knowledge. However, research from several Western countries shows that neither school-based nor university-based teachers are familiar with how to integrate research-based knowledge in professional teacher practice.…

Paper based electronics platform

KAUST Repository

Nassar, Joanna Mohammad; Sevilla, Galo Andres Torres; Hussain, Muhammad Mustafa

2017-01-01

A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors

Cholinesterase-based biosensors.

Science.gov (United States)

Štěpánková, Šárka; Vorčáková, Katarína

2016-01-01

Recently, cholinesterase-based biosensors are widely used for assaying anticholinergic compounds. Primarily biosensors based on enzyme inhibition are useful analytical tools for fast screening of inhibitors, such as organophosphates and carbamates. The present review is aimed at compilation of the most important facts about cholinesterase based biosensors, types of physico-chemical transduction, immobilization strategies and practical applications.

Strengths-based Learning

DEFF Research Database (Denmark)

Ledertoug, Mette Marie

-being. The Ph.D.-project in Strength-based learning took place in a Danish school with 750 pupils age 6-16 and a similar school was functioning as a control group. The presentation will focus on both the aware-explore-apply processes and the practical implications for the schools involved, and on measurable......Strength-based learning - Children͛s Character Strengths as Means to their Learning Potential͛ is a Ph.D.-project aiming to create a strength-based mindset in school settings and at the same time introducing strength-based interventions as specific tools to improve both learning and well...

Using Web-Based Peer Benchmarking to Manage the Client-Based Project

Science.gov (United States)

Raska, David; Keller, Eileen Weisenbach; Shaw, Doris

2013-01-01

The complexities of integrating client-based projects into marketing courses provide challenges for the instructor but produce richness of context and active learning for the student. This paper explains the integration of Web-based peer benchmarking as a means of improving student performance on client-based projects within a single semester in…

Novel nonlinear knowledge-based mean force potentials based on machine learning.

Science.gov (United States)

Dong, Qiwen; Zhou, Shuigeng

2011-01-01

The prediction of 3D structures of proteins from amino acid sequences is one of the most challenging problems in molecular biology. An essential task for solving this problem with coarse-grained models is to deduce effective interaction potentials. The development and evaluation of new energy functions is critical to accurately modeling the properties of biological macromolecules. Knowledge-based mean force potentials are derived from statistical analysis of proteins of known structures. Current knowledge-based potentials are almost in the form of weighted linear sum of interaction pairs. In this study, a class of novel nonlinear knowledge-based mean force potentials is presented. The potential parameters are obtained by nonlinear classifiers, instead of relative frequencies of interaction pairs against a reference state or linear classifiers. The support vector machine is used to derive the potential parameters on data sets that contain both native structures and decoy structures. Five knowledge-based mean force Boltzmann-based or linear potentials are introduced and their corresponding nonlinear potentials are implemented. They are the DIH potential (single-body residue-level Boltzmann-based potential), the DFIRE-SCM potential (two-body residue-level Boltzmann-based potential), the FS potential (two-body atom-level Boltzmann-based potential), the HR potential (two-body residue-level linear potential), and the T32S3 potential (two-body atom-level linear potential). Experiments are performed on well-established decoy sets, including the LKF data set, the CASP7 data set, and the Decoys “R”Us data set. The evaluation metrics include the energy Z score and the ability of each potential to discriminate native structures from a set of decoy structures. Experimental results show that all nonlinear potentials significantly outperform the corresponding Boltzmann-based or linear potentials, and the proposed discriminative framework is effective in developing knowledge-based

Using bio-based polymers for curing cement-based materials

NARCIS (Netherlands)

Zlopasa, J.; Koenders, E.A.B.; Picken, S.J.

2014-01-01

Curing is the process of controlling the rate and extent of moisture loss from the surface of cement based materials. It is the final stage in the production of cement-based materials and it is the essential part for achieving continuous hydration of cement, while avoiding cracking due to drying

Carbon-based sputtered coatings for enhanced chitosan-based films properties

Science.gov (United States)

Fernandes, C.; Calderon V., S.; Ballesteros, Lina F.; Cerqueira, Miguel A.; Pastrana, L. M.; Teixeira, José A.; Ferreira, P. J.; Carvalho, S.

2018-03-01

In order to make bio-based packaging materials competitive in comparison to petroleum-based one, some of their properties need to be improved, among which gas permeability is of crucial importance. Thus, in this work, carbon-based coatings were applied on chitosan-based films by radiofrequency reactive magnetron sputtering aiming to improve their barrier properties. Chemical and morphological properties were evaluated in order to determine the effect of the coatings on the chemical structure, surface hydrophobicity and barrier properties of the system. Chemical analysis, performed by electron energy loss spectroscopy and Fourier transform infrared spectroscopy, suggests similar chemical characteristics among all coatings although higher incorporation of hydrogen as the acetylene flux increases was observed. On the other hand, scanning transmission electron microscopy revealed that the porosity of the carbon layer can be tailored by the acetylene flux. More importantly, the chitosan oxygen permeability showed a monotonic reduction as a function of the acetylene flux. This study opens up new opportunities to apply nanostructured coatings on bio-based polymer for enhanced oxygen barrier properties.

Computer-based teaching is as good as face to face lecture-based teaching of evidence based medicine: a randomised controlled trial

Science.gov (United States)

2007-01-01

Background At postgraduate level evidence based medicine (EBM) is currently taught through tutor based lectures. Computer based sessions fit around doctors' workloads, and standardise the quality of educational provision. There have been no randomized controlled trials comparing computer based sessions with traditional lectures at postgraduate level within medicine. Methods This was a randomised controlled trial involving six postgraduate education centres in the West Midlands, U.K. Fifty five newly qualified foundation year one doctors (U.S internship equivalent) were randomised to either computer based sessions or an equivalent lecture in EBM and systematic reviews. The change from pre to post-intervention score was measured using a validated questionnaire assessing knowledge (primary outcome) and attitudes (secondary outcome). Results Both groups were similar at baseline. Participants' improvement in knowledge in the computer based group was equivalent to the lecture based group (gain in score: 2.1 [S.D = 2.0] versus 1.9 [S.D = 2.4]; ANCOVA p = 0.078). Attitudinal gains were similar in both groups. Conclusion On the basis of our findings we feel computer based teaching and learning is as effective as typical lecture based teaching sessions for educating postgraduates in EBM and systematic reviews. PMID:17659076

A model-based framework for design of intensified enzyme-based processes

DEFF Research Database (Denmark)

Román-Martinez, Alicia

This thesis presents a generic and systematic model-based framework to design intensified enzyme-based processes. The development of the presented methodology was motivated by the needs of the bio-based industry for a more systematic approach to achieve intensification in its production plants...... in enzyme-based processes which have found significant application in the pharmaceutical, food, and renewable fuels sector. The framework uses model-based strategies for (bio)-chemical process design and optimization, including the use of a superstructure to generate all potential reaction......(s)-separation(s) options according to a desired performance criteria and a generic mathematical model represented by the superstructure to derive the specific models corresponding to a specific process option. In principle, three methods of intensification of bioprocess are considered in this thesis: 1. enzymatic one...

Stolen Base Physics

Science.gov (United States)

Kagan, David

2013-01-01

Few plays in baseball are as consistently close and exciting as the stolen base. While there are several studies of sprinting, the art of base stealing is much more nuanced. This article describes the motion of the base-stealing runner using a very basic kinematic model. The model will be compared to some data from a Major League game. The…

An Evidence-Based Assessment of Faith-Based Programs: Do Faith-Based Programs "Work" to Reduce Recidivism?

Science.gov (United States)

Dodson, Kimberly D.; Cabage, Leann N.; Klenowski, Paul M.

2011-01-01

Faith-based organizations administer many of the prison-based programs aimed at reducing recidivism. Many of these organizations also manage treatment programs for substance abusers, at-risk juveniles, and ex-offenders. Much of the research on religiosity and delinquency indicates that the two are inversely related. Therefore, it seems plausible…

Case-based reasoning diagnostic technique based on multi-attribute similarity

Energy Technology Data Exchange (ETDEWEB)

Makoto, Takahashi [Tohoku University, Miyagi (Japan); Akio, Gofuku [Okayama University, Okayamaa (Japan)

2014-08-15

Case-based diagnostic technique has been developed based on the multi-attribute similarity. Specific feature of the developed system is to use multiple attributes of process signals for similarity evaluation to retrieve a similar case stored in a case base. The present technique has been applied to the measurement data from Monju with some simulated anomalies. The results of numerical experiments showed that the present technique can be utilizes as one of the methods for a hybrid-type diagnosis system.

Risk-based safety indicators

International Nuclear Information System (INIS)

Szikszai, T.

1997-01-01

The presentation discusses the following issues: The objectives of the risk-based indicator programme. The characteristics of the risk-based indicators. The objectives of risk-based safety indicators - in monitoring safety; in PSA applications. What indicators? How to produce the risk based indicators? PSA requirements

Supporting Case-Based Learning in Information Security with Web-Based Technology

Science.gov (United States)

He, Wu; Yuan, Xiaohong; Yang, Li

2013-01-01

Case-based learning has been widely used in many disciplines. As an effective pedagogical method, case-based learning is also being used to support teaching and learning in the domain of information security. In this paper, we demonstrate case-based learning in information security by sharing our experiences in using a case study to teach security…

A web-based data-querying tool based on ontology-driven methodology and flowchart-based model.

Science.gov (United States)

Ping, Xiao-Ou; Chung, Yufang; Tseng, Yi-Ju; Liang, Ja-Der; Yang, Pei-Ming; Huang, Guan-Tarn; Lai, Feipei

2013-10-08

Because of the increased adoption rate of electronic medical record (EMR) systems, more health care records have been increasingly accumulating in clinical data repositories. Therefore, querying the data stored in these repositories is crucial for retrieving the knowledge from such large volumes of clinical data. The aim of this study is to develop a Web-based approach for enriching the capabilities of the data-querying system along the three following considerations: (1) the interface design used for query formulation, (2) the representation of query results, and (3) the models used for formulating query criteria. The Guideline Interchange Format version 3.5 (GLIF3.5), an ontology-driven clinical guideline representation language, was used for formulating the query tasks based on the GLIF3.5 flowchart in the Protégé environment. The flowchart-based data-querying model (FBDQM) query execution engine was developed and implemented for executing queries and presenting the results through a visual and graphical interface. To examine a broad variety of patient data, the clinical data generator was implemented to automatically generate the clinical data in the repository, and the generated data, thereby, were employed to evaluate the system. The accuracy and time performance of the system for three medical query tasks relevant to liver cancer were evaluated based on the clinical data generator in the experiments with varying numbers of patients. In this study, a prototype system was developed to test the feasibility of applying a methodology for building a query execution engine using FBDQMs by formulating query tasks using the existing GLIF. The FBDQM-based query execution engine was used to successfully retrieve the clinical data based on the query tasks formatted using the GLIF3.5 in the experiments with varying numbers of patients. The accuracy of the three queries (ie, "degree of liver damage," "degree of liver damage when applying a mutually exclusive setting

Feature-Based Analysis of Plasma-Based Particle Acceleration Data

Energy Technology Data Exchange (ETDEWEB)

Rubel, Oliver [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Geddes, Cameron G. R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chen, Min [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cormier-Michel, Estelle [Tech-X Corp., Boulder, CO (United States); Bethel, E. Wes [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2014-02-01

Plasma-based particle accelerators can produce and sustain thousands of times stronger acceleration fields than conventional particle accelerators, providing a potential solution to the problem of the growing size and cost of conventional particle accelerators. To facilitate scientific knowledge discovery from the ever growing collections of accelerator simulation data generated by accelerator physicists to investigate next-generation plasma-based particle accelerator designs, we describe a novel approach for automatic detection and classification of particle beams and beam substructures due to temporal differences in the acceleration process, here called acceleration features. The automatic feature detection in combination with a novel visualization tool for fast, intuitive, query-based exploration of acceleration features enables an effective top-down data exploration process, starting from a high-level, feature-based view down to the level of individual particles. We describe the application of our analysis in practice to analyze simulations of single pulse and dual and triple colliding pulse accelerator designs, and to study the formation and evolution of particle beams, to compare substructures of a beam and to investigate transverse particle loss.

Convex-based void filling method for CAD-based Monte Carlo geometry modeling

International Nuclear Information System (INIS)

Yu, Shengpeng; Cheng, Mengyun; Song, Jing; Long, Pengcheng; Hu, Liqin

2015-01-01

Highlights: • We present a new void filling method named CVF for CAD based MC geometry modeling. • We describe convex based void description based and quality-based space subdivision. • The results showed improvements provided by CVF for both modeling and MC calculation efficiency. - Abstract: CAD based automatic geometry modeling tools have been widely applied to generate Monte Carlo (MC) calculation geometry for complex systems according to CAD models. Automatic void filling is one of the main functions in the CAD based MC geometry modeling tools, because the void space between parts in CAD models is traditionally not modeled while MC codes such as MCNP need all the problem space to be described. A dedicated void filling method, named Convex-based Void Filling (CVF), is proposed in this study for efficient void filling and concise void descriptions. The method subdivides all the problem space into disjointed regions using Quality based Subdivision (QS) and describes the void space in each region with complementary descriptions of the convex volumes intersecting with that region. It has been implemented in SuperMC/MCAM, the Multiple-Physics Coupling Analysis Modeling Program, and tested on International Thermonuclear Experimental Reactor (ITER) Alite model. The results showed that the new method reduced both automatic modeling time and MC calculation time

Knowledge base mechanisms

Energy Technology Data Exchange (ETDEWEB)

Suwa, M; Furukawa, K; Makinouchi, A; Mizoguchi, T; Mizoguchi, F; Yamasaki, H

1982-01-01

One of the principal goals of the Fifth Generation Computer System Project for the coming decade is to develop a methodology for building knowledge information processing systems which will provide people with intelligent agents. The key notion of the fifth generation computer system is knowledge used for problem solving. In this paper the authors describe the plan of Randd on knowledge base mechanisms. A knowledge representation system is to be designed to support knowledge acquisition for the knowledge information processing systems. The system will include a knowledge representation language, a knowledge base editor and a debugger. It is also expected to perform as a kind of meta-inference system. In order to develop the large scale knowledge base systems, a knowledge base mechanism based on the relational model is to be studied in the earlier stage of the project. Distributed problem solving is also one of the main issues of the project. 19 references.

Iron-based amorphous alloys and methods of synthesizing iron-based amorphous alloys

Science.gov (United States)

Saw, Cheng Kiong; Bauer, William A.; Choi, Jor-Shan; Day, Dan; Farmer, Joseph C.

2016-05-03

A method according to one embodiment includes combining an amorphous iron-based alloy and at least one metal selected from a group consisting of molybdenum, chromium, tungsten, boron, gadolinium, nickel phosphorous, yttrium, and alloys thereof to form a mixture, wherein the at least one metal is present in the mixture from about 5 atomic percent (at %) to about 55 at %; and ball milling the mixture at least until an amorphous alloy of the iron-based alloy and the at least one metal is formed. Several amorphous iron-based metal alloys are also presented, including corrosion-resistant amorphous iron-based metal alloys and radiation-shielding amorphous iron-based metal alloys.

Comparing grapheme-based and phoneme-based speech recognition for Afrikaans

CSIR Research Space (South Africa)

Basson, WD

2012-11-01

Full Text Available This paper compares the recognition accuracy of a phoneme-based automatic speech recognition system with that of a grapheme-based system, using Afrikaans as case study. The first system is developed using a conventional pronunciation dictionary...

Culture and group-based emotions: could group-based emotions be dialectical?

Science.gov (United States)

Lu, Minjie; Hamamura, Takeshi; Doosje, Bertjan; Suzuki, Satoko; Takemura, Kosuke

2017-08-01

Group-based emotions are experienced when individuals are engaged in emotion-provoking events that implicate the in-group. This research examines the complexity of group-based emotions, specifically a concurrence of positive and negative emotions, focusing on the role of dialecticism, or a set of folk beliefs prevalent in Asian cultures that views nature and objects as constantly changing, inherently contradictory, and fundamentally interconnected. Study 1 found that dialecticism is positively associated with the complexity of Chinese participants' group-based emotions after reading a scenario depicting a positive intergroup experience. Study 2 found that Chinese participants experienced more complex group-based emotions compared with Dutch participants in an intergroup situation and that this cultural difference was mediated by dialecticism. Study 3 manipulated dialecticism and confirmed its causal effect on complex group-based emotions. These studies also suggested the role of a balanced appraisal of an intergroup situation as a mediating factor.

Interdisciplinarity in translation teaching: competence-based education, translation task-based approach, context-based text typology

Directory of Open Access Journals (Sweden)

Edelweiss Vitol Gysel

2017-05-01

Full Text Available In the context of competence-based teaching, this paper draws upon the model of Translation Competence (TC put forward by the PACTE group (2003 to establish a dialogue between cognitive-constructivist paradigms for translation teaching and the model of the Context-based Text Typology (MATTHIESSEN et al., 2007. In this theoretical environment, it proposes a model for the design of a Teaching Unit (TU for the development of the bilingual competence in would-be-translators.To this end, it explores translation as a cognitive, communicative and textual activity (HURTADO ALBIR, 2011 and considers its teaching from the translation task-based approach (HURTADO ALBIR, 1999. This approach is illustrated through the practical example of the design of a TU elaborated for the subject ‘Introduction to Specialized Translation’,part of the curricular grid of the program ‘Secretariado Executivo’ at Universidade Federal de Santa Catarina. Aspects such as the establishment of learning objectives and their alignment with the translation tasks composing the TU are addressed for this specific pedagogical situation. We argue for the development of textual competences by means of the acquisition of strategies derived from the Context-based Text Typology to solve problems arising from the translation of different text types and contextual configurations.

Evidence-Based Toxicology.

Science.gov (United States)

Hoffmann, Sebastian; Hartung, Thomas; Stephens, Martin

Evidence-based toxicology (EBT) was introduced independently by two groups in 2005, in the context of toxicological risk assessment and causation as well as based on parallels between the evaluation of test methods in toxicology and evidence-based assessment of diagnostics tests in medicine. The role model of evidence-based medicine (EBM) motivated both proposals and guided the evolution of EBT, whereas especially systematic reviews and evidence quality assessment attract considerable attention in toxicology.Regarding test assessment, in the search of solutions for various problems related to validation, such as the imperfectness of the reference standard or the challenge to comprehensively evaluate tests, the field of Diagnostic Test Assessment (DTA) was identified as a potential resource. DTA being an EBM discipline, test method assessment/validation therefore became one of the main drivers spurring the development of EBT.In the context of pathway-based toxicology, EBT approaches, given their objectivity, transparency and consistency, have been proposed to be used for carrying out a (retrospective) mechanistic validation.In summary, implementation of more evidence-based approaches may provide the tools necessary to adapt the assessment/validation of toxicological test methods and testing strategies to face the challenges of toxicology in the twenty first century.

Aperiodic-metamaterial-based absorber

Directory of Open Access Journals (Sweden)

Quanlong Yang

2017-09-01

Full Text Available The periodic-metamaterial-based perfect absorber has been studied broadly. Conversely, if the unit cell in the metamaterial-based absorber is arranged aperiodically (aperiodic-metamaterial-based absorber, how does it perform? Inspired by this, here we present a systematic study of the aperiodic-metamaterial-based absorber. By investigating the response of metamaterial absorbers based on periodic, Fibonacci, Thue-Morse, and quasicrystal lattices, we found that aperiodic-metamaterial-based absorbers could display similar absorption behaviors as the periodic one in one hand. However, their absorption behaviors show different tendency depending on the thicknesses of the spacer. Further studies on the angle and polarization dependence of the absorption behavior are also presented.

Concurrent array-based queue

Science.gov (United States)

Heidelberger, Philip; Steinmacher-Burow, Burkhard

2015-01-06

According to one embodiment, a method for implementing an array-based queue in memory of a memory system that includes a controller includes configuring, in the memory, metadata of the array-based queue. The configuring comprises defining, in metadata, an array start location in the memory for the array-based queue, defining, in the metadata, an array size for the array-based queue, defining, in the metadata, a queue top for the array-based queue and defining, in the metadata, a queue bottom for the array-based queue. The method also includes the controller serving a request for an operation on the queue, the request providing the location in the memory of the metadata of the queue.

Metal-mediated DNA base pairing: alternatives to hydrogen-bonded Watson-Crick base pairs.

Science.gov (United States)

Takezawa, Yusuke; Shionoya, Mitsuhiko

2012-12-18

With its capacity to store and transfer the genetic information within a sequence of monomers, DNA forms its central role in chemical evolution through replication and amplification. This elegant behavior is largely based on highly specific molecular recognition between nucleobases through the specific hydrogen bonds in the Watson-Crick base pairing system. While the native base pairs have been amazingly sophisticated through the long history of evolution, synthetic chemists have devoted considerable efforts to create alternative base pairing systems in recent decades. Most of these new systems were designed based on the shape complementarity of the pairs or the rearrangement of hydrogen-bonding patterns. We wondered whether metal coordination could serve as an alternative driving force for DNA base pairing and why hydrogen bonding was selected on Earth in the course of molecular evolution. Therefore, we envisioned an alternative design strategy: we replaced hydrogen bonding with another important scheme in biological systems, metal-coordination bonding. In this Account, we provide an overview of the chemistry of metal-mediated base pairing including basic concepts, molecular design, characteristic structures and properties, and possible applications of DNA-based molecular systems. We describe several examples of artificial metal-mediated base pairs, such as Cu(2+)-mediated hydroxypyridone base pair, H-Cu(2+)-H (where H denotes a hydroxypyridone-bearing nucleoside), developed by us and other researchers. To design the metallo-base pairs we carefully chose appropriate combinations of ligand-bearing nucleosides and metal ions. As expected from their stronger bonding through metal coordination, DNA duplexes possessing metallo-base pairs exhibited higher thermal stability than natural hydrogen-bonded DNAs. Furthermore, we could also use metal-mediated base pairs to construct or induce other high-order structures. These features could lead to metal-responsive functional

Selective Sequential Zero-Base Budgeting Procedures Based on Total Factor Productivity Indicators

OpenAIRE

A. Ishikawa; E. F. Sudit

1981-01-01

The authors' purpose in this paper is to develop productivity-based sequential budgeting procedures designed to expedite identification of major problem areas in bugetary performance, as well as to reduce the costs associated with comprehensive zero-base analyses. The concept of total factor productivity is reviewed and its relations to ordinary and zero-based budgeting are discussed in detail. An outline for a selective sequential analysis based on monitoring of three key indicators of (a) i...

Replacing fossil based plastic performance products by bio-based plastic products-Technical feasibility.

Science.gov (United States)

van den Oever, Martien; Molenveld, Karin

2017-07-25

Larger scale market introduction of new bio-based products requires a clear advantage regarding sustainability, as well as an adequate techno-economic positioning relative to fossil based products. In a previous paper [Broeren et al., 2016], LCA results per kg and per functionality equivalent of bio-based plastics were presented, together with economic considerations. The present paper discusses the mechanical and thermal properties of a range of commercially available bio-based plastics based on polylactic acid (PLA), cellulose esters, starch and polyamides, and the feasibility of replacing fossil-based counterparts based on performance. The evaluation is approached from an end user perspective. First, potentially suitable bio-based plastics are selected based on manufacturers' specifications in technical data sheets, then a first experimental evaluation is performed on injection moulded ISO specimens, and finally a further selection of plastics is tested on large 50×70cm panels. This technical feasibility study indicates that so far bio-based plastics do not completely match the properties of high performance materials like flame retardant V-0 PC/ABS blends used in electronic devices. The performance gap is being decreased by the development of stereocomplex PLA and hybrid PLA blends with polycarbonate, which offer clearly improved properties with respect to maximum usage temperature and toughness. In addition, several materials meet the V-0 flammability requirements needed in specific durable applications. On the other hand, improving these properties so far has negative consequences for the bio-based content. This study also shows that replacement of bulk polymers like PS is feasible using PLA compounds with a bio-based content as high as 85%. Copyright © 2016 Elsevier B.V. All rights reserved.

From scientifically based research to evidence based learning

Directory of Open Access Journals (Sweden)

Rosa Cera

2016-02-01

Full Text Available This essay is a reflection on the peculiarities of the scientifically based research and on the distinctive elements of the EBL (evidence based learning, methodology used in the study on the “Relationship between Metacognition, Self-efficacy and Self-regulation in Learning”. The EBL method, based on the standardization of data, explains how the students’ learning experience can be considered as a set of “data” and can be used to explain how and when the research results can be considered generalizable and transferable to other learning situations. The reflections present in this study have also allowed us to illustrate the impact that its results have had on the micro and macro level of reality. They helped to fill in the gaps concerning the learning/teaching processes, contributed to the enrichment of the scientific literature on this subject and allowed to establish standards through rigorous techniques such as systematic reviews and meta-analysis.

Space Launch System Base Heating Test: Environments and Base Flow Physics

Science.gov (United States)

Mehta, Manish; Knox, Kyle S.; Seaford, C. Mark; Dufrene, Aaron T.

2016-01-01

The NASA Space Launch System (SLS) vehicle is composed of four RS-25 liquid oxygen- hydrogen rocket engines in the core-stage and two 5-segment solid rocket boosters and as a result six hot supersonic plumes interact within the aft section of the vehicle during ight. Due to the complex nature of rocket plume-induced ows within the launch vehicle base during ascent and a new vehicle con guration, sub-scale wind tunnel testing is required to reduce SLS base convective environment uncertainty and design risk levels. This hot- re test program was conducted at the CUBRC Large Energy National Shock (LENS) II short-duration test facility to simulate ight from altitudes of 50 kft to 210 kft. The test program is a challenging and innovative e ort that has not been attempted in 40+ years for a NASA vehicle. This presentation discusses the various trends of base convective heat ux and pressure as a function of altitude at various locations within the core-stage and booster base regions of the two-percent SLS wind tunnel model. In-depth understanding of the base ow physics is presented using the test data, infrared high-speed imaging and theory. The normalized test design environments are compared to various NASA semi- empirical numerical models to determine exceedance and conservatism of the ight scaled test-derived base design environments. Brief discussion of thermal impact to the launch vehicle base components is also presented.

The physics data base

International Nuclear Information System (INIS)

Gault, F.D.

1984-01-01

The physics data base is introduced along with its associated data base management system. The emphasis is on data and their use and a classification of data and of data bases is developed to distinguish compilation organizations. The characteristics of these organizations are examined briefly and the long term consequences of the physics data base discussed. (orig.)

Characteristic properties of Fibonacci-based mutually unbiased bases

Energy Technology Data Exchange (ETDEWEB)

Seyfarth, Ulrich; Alber, Gernot [Institut fuer Angewandte Physik, Technische Universitaet Darmstadt, 64289 Darmstadt (Germany); Ranade, Kedar [Institut fuer Quantenphysik, Universitaet Ulm, Albert-Einstein-Allee 11, 89069 Ulm (Germany)

2012-07-01

Complete sets of mutually unbiased bases (MUBs) offer interesting applications in quantum information processing ranging from quantum cryptography to quantum state tomography. Different construction schemes provide different perspectives on these bases which are typically also deeply connected to various mathematical research areas. In this talk we discuss characteristic properties resulting from a recently established connection between construction methods for cyclic MUBs and Fibonacci polynomials. As a remarkable fact this connection leads to construction methods which do not involve any relations to mathematical properties of finite fields.

Querying archetype-based EHRs by search ontology-based XPath engineering.

Science.gov (United States)

Kropf, Stefan; Uciteli, Alexandr; Schierle, Katrin; Krücken, Peter; Denecke, Kerstin; Herre, Heinrich

2018-05-11

Legacy data and new structured data can be stored in a standardized format as XML-based EHRs on XML databases. Querying documents on these databases is crucial for answering research questions. Instead of using free text searches, that lead to false positive results, the precision can be increased by constraining the search to certain parts of documents. A search ontology-based specification of queries on XML documents defines search concepts and relates them to parts in the XML document structure. Such query specification method is practically introduced and evaluated by applying concrete research questions formulated in natural language on a data collection for information retrieval purposes. The search is performed by search ontology-based XPath engineering that reuses ontologies and XML-related W3C standards. The key result is that the specification of research questions can be supported by the usage of search ontology-based XPath engineering. A deeper recognition of entities and a semantic understanding of the content is necessary for a further improvement of precision and recall. Key limitation is that the application of the introduced process requires skills in ontology and software development. In future, the time consuming ontology development could be overcome by implementing a new clinical role: the clinical ontologist. The introduced Search Ontology XML extension connects Search Terms to certain parts in XML documents and enables an ontology-based definition of queries. Search ontology-based XPath engineering can support research question answering by the specification of complex XPath expressions without deep syntax knowledge about XPaths.

Problem Based Learning

DEFF Research Database (Denmark)

de Graaff, Erik; Guerra, Aida

, the key principles remain the same everywhere. Graaff & Kolmos (2003) identify the main PBL principles as follows: 1. Problem orientation 2. Project organization through teams or group work 3. Participant-directed 4. Experiental learning 5. Activity-based learning 6. Interdisciplinary learning and 7...... model and in general problem based and project based learning. We apply the principle of teach as you preach. The poster aims to outline the visitors’ workshop programme showing the results of some recent evaluations.......Problem-Based Learning (PBL) is an innovative method to organize the learning process in such a way that the students actively engage in finding answers by themselves. During the past 40 years PBL has evolved and diversified resulting in a multitude in variations in models and practices. However...

High stability vector-based direct power control for DFIG-based wind turbine

DEFF Research Database (Denmark)

Zhu, Rongwu; Chen, Zhe; Wu, Xiaojie

2015-01-01

This paper proposes an improved vector-based direct power control (DPC) strategy for the doubly-fed induction generator (DFIG)-based wind energy conversion system. Based on the small signal model, the proposed DPC improves the stability of the DFIG, and avoids the DFIG operating in the marginal...

Research on Fault Diagnosis Method Based on Rule Base Neural Network

Directory of Open Access Journals (Sweden)

Zheng Ni

2017-01-01

Full Text Available The relationship between fault phenomenon and fault cause is always nonlinear, which influences the accuracy of fault location. And neural network is effective in dealing with nonlinear problem. In order to improve the efficiency of uncertain fault diagnosis based on neural network, a neural network fault diagnosis method based on rule base is put forward. At first, the structure of BP neural network is built and the learning rule is given. Then, the rule base is built by fuzzy theory. An improved fuzzy neural construction model is designed, in which the calculated methods of node function and membership function are also given. Simulation results confirm the effectiveness of this method.

A comparative review of petroleum-based and bio-based acrolein production.

Science.gov (United States)

Liu, Lu; Ye, X Philip; Bozell, Joseph J

2012-07-01

Acrolein is an important chemical intermediate for many common industrial chemicals, leading to an array of useful end products. This paper reviews all the synthetic methods, including the former (aldol condensation) and contemporary (partial oxidation of propylene) manufacturing methods, the partial oxidation of propane, and most importantly, the bio-based glycerol-dehydration route. Emphasis is placed on the petroleum-based route from propylene and the bio-based route from glycerol, an abundantly available and relatively inexpensive raw material available from biodiesel production. This review provides technical details and incentives for industrial proyduction that justify a transition toward bio-based acrolein production. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Value-based pricing

OpenAIRE

Netseva-Porcheva Tatyana

2010-01-01

The main aim of the paper is to present the value-based pricing. Therefore, the comparison between two approaches of pricing is made - cost-based pricing and value-based pricing. The 'Price sensitively meter' is presented. The other topic of the paper is the perceived value - meaning of the perceived value, the components of perceived value, the determination of perceived value and the increasing of perceived value. In addition, the best company strategies in matrix 'value-cost' are outlined. .

Research-based design & design-based research: Affordances, limitations and synergies

NARCIS (Netherlands)

McKenney, Susan

2015-01-01

Research-based design is an orientation to educational development that is explicitly informed by existing research as well as formative evaluation. Design-based research is a genre of inquiry in which the design of innovative solutions to problems in educational practice provides the context for

Autopsy practice in forensic pathology - Evidence-based or experience-based?

DEFF Research Database (Denmark)

Colville-Ebeling, Bonnie; Freeman, Michael; Banner, Jytte

2014-01-01

Current autopsy practice in forensic pathology is to a large extent based on experience and individual customary practices as opposed to evidence and consensus based practices. As a result there is the potential for substantial variation in how knowledge is applied in each case. In the present case......-gathering and the use of check lists specific to certain injury causes are likely to result in less deviation from evidence-based practices in forensic pathology. Pre-autopsy data-gathering and check lists will help ensure a higher degree of standardization in autopsy reports thus enhancing the quality and accuracy...

Value-based management: Theoretical base, shareholders' request and the concept

Directory of Open Access Journals (Sweden)

Kaličanin Đorđe M.

2005-01-01

Full Text Available The pressure of financial markets, which is a consequence of shareholder revolution, directly affects the solution to the following dilemma: is the mission of corporations to maximize shareholders' wealth or to satisfy interests of other stakeholders? The domination of shareholder theory has caused the appearance of the valuebased management concept. Value-based management is a relevant concept and a process of management in modern environment. The importance of shareholder value requires transformation of traditional enterprise into value driven enterprise. This paper addresses theoretical base, shareholder revolution and the main characteristics of value-based management.

Elucidating the hard/soft acid/base principle: A perspective based on half-reactions

International Nuclear Information System (INIS)

Ayers, Paul W.; Parr, Robert G.; Pearson, Ralph G.

2006-01-01

A comprehensive analysis is presented for the acid-base double-exchange reaction as well as the associated acid-displacement and base-displacement 'half-reactions' with the goal of elucidating the meaning of the hard/soft acid/base (HSAB) principle and the conditions for its validity. When electron-transfer effects are important and other effects are negligible, the HSAB principle is driven by the surpassing stability of the soft acid/soft base product. When electrostatic effects dominate the reactivity, the HSAB principle is driven by the surpassing stability of the hard acid/hard base product. Because electron-transfer effects favor soft/soft interactions, while electrostatic effects favor hard/hard interactions, acid-base exchange reactions may be used to determine whether a reagent's reactivity is dominated by electron-transfer or by electrostatic effects. Because electron-transfer and electrostatic considerations separately favor the HSAB principle whenever the electronic chemical potentials of the acids and bases involved in the reaction are similar, our analysis provides strong support for the HSAB principle. The electronic chemical potential measures the intrinsic strength of acids and bases

Synthesis of Graft Copolymers by Small Doses of Irradiation; Synthese des copolymeres greffes au moyen de petites doses de rayonnements; Sintez privitykh sopolimerov s pomoshch'yu malykh doz oblucheniya; Sintesis de copolimeros de injerto mediante pequenas dosis de radiacion

Energy Technology Data Exchange (ETDEWEB)

Dobo, J; Somogyi, M; Kiss, L

1960-07-15

In addition to grafting, there is often an undesirable alteration in the properties of the original polymer when polymer monomer mixtures are irradiated. As a result of irradiation, grafting occurs not only on the original polymeric backbone, but also on the already grafted side-chains. The result is an acceleration of grafting. The effect is especially pronounced in the case of preformed polymers, if irradiation is carried out intermittently. The grafting of styrene can be accelerated by the addition of some solvents which suppress the protective effect of the styrene on the polymer. Grafting can be accelerated by other additives. The swelling properties of the irradiated films were investigated. (author) [French] Lorsque des melanges de polymeres et de monomeres sont soumis a des rayonnements, il se produit souvent, en meme temps que la greffe, une alteration facheuse des proprietes du polymere original. L'irradiation provoque une reaction de greffage, non seulement sur le polymere original, mais aussi sur les chaines laterales deja greffees. Il en resulte une acceleration du processus de greffage. L'effet est particulierement marque dans le cas des polymeres preformes, lorsque l'irradiation est effectuee par intermittence. On peut accelerer le processus de greffage du styrolene en ajoutant certains solvants qui suppriment l'action protectrice du styrolene sur le polymere. On peut aussi accelerer le processus a l'aide d'autres additifs. Les auteurs ont etudie les proprietes de gonflement des pellicules irradiees. (author) [Spanish] Simultaneamente con el injerto, bajo la accion de las radiaciones se produce frecuentemente una alteracion de las propiedades del polimero original, efecto que convendria evitar. Por lo tanto, quiza ofrezcan interes los elevados grados de injerto obtenidos en nuestros laboratorios con pequenas dosis de radiacion. La irradiacion no solo provoca una reaccion de injerto en la estructura polimerica original, sino tambien en las cadenas laterales injertadas. Ello se traduce en una aceleracion, del proceso de injerto. Este efecto es especialmente pronunciado en el caso de los polimeros preformados, cuando la irradiacion es intermitente. El injerto de las moleculas de estireno puede acelerarse anadiendo algunos solventes que suprimen la accion protectora ejercida por el estireno sobre el polimero. Asimismo, el proceso puede acelerarse agregando otras sustancias. Al injertar moleculas de metacrilato de metilo en el polietileno, hemos conseguido un injerto de 6 400 por ciento con una dosis de 31 400 roentgens. Hemos examinado la estructura de los copolimeros asi obtenidos. (author) [Russian] Grafting (privivanie ) chasto soprovozhdaetsya nezhelatel'nym izmeneniem svojstv pervonachal'nogo polimera pri obluchenii monomernykh smesej polimera. Pod vozdejstviem oblucheniya grafting proiskhodit ne tol'ko v pervonachal'noj polimernoj osnove, no takzhe v bokovoj tsepi, uzhe podvergnuvshejsya graftingu. Grafting v rezul'tate ehtogo uskoryaetsya. EHtot ehffekt osobenno yarko vyrazhen v tverdykh polimerakh, esli obluchenie proizvoditsya periodicheski. Grafting stirola mozhet byt' uskoren dobavleniem nekotorykh rastvoritelej, kotorye blokiruyut zashchitnoe vozdejstvie stirola na dannyj polimer. Grafting mozhet byt' uskoren i drugimi additivami. Issleduyutsya kachestva nabukhaniya obluchennoj plenki. (author)

Base-By-Base: single nucleotide-level analysis of whole viral genome alignments.

Science.gov (United States)

Brodie, Ryan; Smith, Alex J; Roper, Rachel L; Tcherepanov, Vasily; Upton, Chris

2004-07-14

With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than gene content because two strains of an organism may share the same set of predicted genes but still differ in their pathogenicity profiles. For example, detailed comparison of multiple isolates of the smallpox virus genome (each approximately 200 kb, with 200 genes) is not feasible without new bioinformatics tools. A software package, Base-By-Base, has been developed that provides visualization tools to enable researchers to 1) rapidly identify and correct alignment errors in large, multiple genome alignments; and 2) generate tabular and graphical output of differences between the genomes at the nucleotide level. Base-By-Base uses detailed annotation information about the aligned genomes and can list each predicted gene with nucleotide differences, display whether variations occur within promoter regions or coding regions and whether these changes result in amino acid substitutions. Base-By-Base can connect to our mySQL database (Virus Orthologous Clusters; VOCs) to retrieve detailed annotation information about the aligned genomes or use information from text files. Base-By-Base enables users to quickly and easily compare large viral genomes; it highlights small differences that may be responsible for important phenotypic differences such as virulence. It is available via the Internet using Java Web Start and runs on Macintosh, PC and Linux operating systems with the Java 1.4 virtual machine.

Value-based pricing

Directory of Open Access Journals (Sweden)

Netseva-Porcheva Tatyana

2010-01-01

Full Text Available The main aim of the paper is to present the value-based pricing. Therefore, the comparison between two approaches of pricing is made - cost-based pricing and value-based pricing. The 'Price sensitively meter' is presented. The other topic of the paper is the perceived value - meaning of the perceived value, the components of perceived value, the determination of perceived value and the increasing of perceived value. In addition, the best company strategies in matrix 'value-cost' are outlined. .

An Analysis of Delay-based and Integrator-based Sequence Detectors for Grid-Connected Converters

DEFF Research Database (Denmark)

Khazraj, Hesam; Silva, Filipe Miguel Faria da; Bak, Claus Leth

2017-01-01

-signal cancellation operators are the main members of the delay-based sequence detectors. The aim of this paper is to provide a theoretical and experimental comparative study between integrator and delay based sequence detectors. The theoretical analysis is conducted based on the small-signal modelling......Detecting and separating positive and negative sequence components of the grid voltage or current is of vital importance in the control of grid-connected power converters, HVDC systems, etc. To this end, several techniques have been proposed in recent years. These techniques can be broadly...... classified into two main classes: The integrator-based techniques and Delay-based techniques. The complex-coefficient filter-based technique, dual second-order generalized integrator-based method, multiple reference frame approach are the main members of the integrator-based sequence detector and the delay...

Gender-based violence and the need for evidence-based primary ...

African Journals Online (AJOL)

Gender-based violence is a significant problem globally and in South Africa. The public and political discourse has been dominated by calls for increased penalties and convictions for perpetrators of various types of gender-based violence. However, these responses are unlikely to prevent such violence from occurring in ...

Skull base tumours part I: Imaging technique, anatomy and anterior skull base tumours

Energy Technology Data Exchange (ETDEWEB)

Borges, Alexandra [Instituto Portugues de Oncologia Francisco Gentil, Centro de Lisboa, Servico de Radiologia, Rua Professor Lima Basto, 1093 Lisboa Codex (Portugal)], E-mail: borgesalexandra@clix.pt

2008-06-15

Advances in cross-sectional imaging, surgical technique and adjuvant treatment have largely contributed to ameliorate the prognosis, lessen the morbidity and mortality of patients with skull base tumours and to the growing medical investment in the management of these patients. Because clinical assessment of the skull base is limited, cross-sectional imaging became indispensable in the diagnosis, treatment planning and follow-up of patients with suspected skull base pathology and the radiologist is increasingly responsible for the fate of these patients. This review will focus on the advances in imaging technique; contribution to patient's management and on the imaging features of the most common tumours affecting the anterior skull base. Emphasis is given to a systematic approach to skull base pathology based upon an anatomic division taking into account the major tissue constituents in each skull base compartment. The most relevant information that should be conveyed to surgeons and radiation oncologists involved in patient's management will be discussed.

Applications of lipid based formulation technologies in the delivery of biotechnology-based therapeutics.

Science.gov (United States)

du Plessis, Lissinda H; Marais, Etienne B; Mohammed, Faruq; Kotzé, Awie F

2014-01-01

In the last decades several new biotechnologically-based therapeutics have been developed due to progress in genetic engineering. A growing challenge facing pharmaceutical scientists is formulating these compounds into oral dosage forms with adequate bioavailability. An increasingly popular approach to formulate biotechnology-based therapeutics is the use of lipid based formulation technologies. This review highlights the importance of lipid based drug delivery systems in the formulation of oral biotechnology based therapeutics including peptides, proteins, DNA, siRNA and vaccines. The different production procedures used to achieve high encapsulation efficiencies of the bioactives are discussed, as well as the factors influencing the choice of excipient. Lipid based colloidal drug delivery systems including liposomes and solid lipid nanoparticles are reviewed with a focus on recent advances and updates. We further describe microemulsions and self-emulsifying drug delivery systems and recent findings on bioactive delivery. We conclude the review with a few examples on novel lipid based formulation technologies.

Skull base tumours part I: Imaging technique, anatomy and anterior skull base tumours

International Nuclear Information System (INIS)

Borges, Alexandra

2008-01-01

Advances in cross-sectional imaging, surgical technique and adjuvant treatment have largely contributed to ameliorate the prognosis, lessen the morbidity and mortality of patients with skull base tumours and to the growing medical investment in the management of these patients. Because clinical assessment of the skull base is limited, cross-sectional imaging became indispensable in the diagnosis, treatment planning and follow-up of patients with suspected skull base pathology and the radiologist is increasingly responsible for the fate of these patients. This review will focus on the advances in imaging technique; contribution to patient's management and on the imaging features of the most common tumours affecting the anterior skull base. Emphasis is given to a systematic approach to skull base pathology based upon an anatomic division taking into account the major tissue constituents in each skull base compartment. The most relevant information that should be conveyed to surgeons and radiation oncologists involved in patient's management will be discussed

Comparison of MRI-based and CT/MRI fusion-based postimplant dosimetric analysis of prostate brachytherapy

International Nuclear Information System (INIS)

Tanaka, Osamu; Hayashi, Shinya; Matsuo, Masayuki; Sakurai, Kota; Nakano, Masahiro; Maeda, Sunaho; Kajita, Kimihiro R.T.; Deguchi, Takashi; Hoshi, Hiroaki

2006-01-01

Purpose: The aim of this study was to compare the outcomes between magnetic resonance imaging (MRI)-based and computed tomography (CT)/MRI fusion-based postimplant dosimetry methods in permanent prostate brachytherapy. Methods and Materials: Between October 2004 and March 2006, a total of 52 consecutive patients with prostate cancer were treated by brachytherapy, and postimplant dosimetry was performed using CT/MRI fusion. The accuracy and reproducibility were prospectively compared between MRI-based dosimetry and CT/MRI fusion-based dosimetry based on the dose-volume histogram (DVH) related parameters as recommended by the American Brachytherapy Society. Results: The prostate volume was 15.97 ± 6.17 cc (mean ± SD) in MRI-based dosimetry, and 15.97 ± 6.02 cc in CT/MRI fusion-based dosimetry without statistical difference. The prostate V100 was 94.5% and 93.0% in MRI-based and CT/MRI fusion-based dosimetry, respectively, and the difference was statistically significant (p = 0.002). The prostate D90 was 119.4% and 114.4% in MRI-based and CT/MRI fusion-based dosimetry, respectively, and the difference was statistically significant (p = 0.004). Conclusion: Our current results suggested that, as with fusion images, MR images allowed accurate contouring of the organs, but they tended to overestimate the analysis of postimplant dosimetry in comparison to CT/MRI fusion images. Although this MRI-based dosimetric discrepancy was negligible, MRI-based dosimetry was acceptable and reproducible in comparison to CT-based dosimetry, because the difference between MRI-based and CT/MRI fusion-based results was smaller than that between CT-based and CT/MRI fusion-based results as previously reported

Problem-Oriented Corporate Knowledge Base Models on the Case-Based Reasoning Approach Basis

Science.gov (United States)

Gluhih, I. N.; Akhmadulin, R. K.

2017-07-01

One of the urgent directions of efficiency enhancement of production processes and enterprises activities management is creation and use of corporate knowledge bases. The article suggests a concept of problem-oriented corporate knowledge bases (PO CKB), in which knowledge is arranged around possible problem situations and represents a tool for making and implementing decisions in such situations. For knowledge representation in PO CKB a case-based reasoning approach is encouraged to use. Under this approach, the content of a case as a knowledge base component has been defined; based on the situation tree a PO CKB knowledge model has been developed, in which the knowledge about typical situations as well as specific examples of situations and solutions have been represented. A generalized problem-oriented corporate knowledge base structural chart and possible modes of its operation have been suggested. The obtained models allow creating and using corporate knowledge bases for support of decision making and implementing, training, staff skill upgrading and analysis of the decisions taken. The universal interpretation of terms “situation” and “solution” adopted in the work allows using the suggested models to develop problem-oriented corporate knowledge bases in different subject domains. It has been suggested to use the developed models for making corporate knowledge bases of the enterprises that operate engineer systems and networks at large production facilities.

Web-Based Learning Environment Based on Students’ Needs

Science.gov (United States)

Hamzah, N.; Ariffin, A.; Hamid, H.

2017-08-01

Traditional learning needs to be improved since it does not involve active learning among students. Therefore, in the twenty-first century, the development of internet technology in the learning environment has become the main needs of each student. One of the learning environments to meet the needs of the teaching and learning process is a web-based learning environment. This study aims to identify the characteristics of a web-based learning environment that supports students’ learning needs. The study involved 542 students from fifteen faculties in a public higher education institution in Malaysia. A quantitative method was used to collect the data via a questionnaire survey by randomly. The findings indicate that the characteristics of a web-based learning environment that support students’ needs in the process of learning are online discussion forum, lecture notes, assignments, portfolio, and chat. In conclusion, the students overwhelmingly agreed that online discussion forum is the highest requirement because the tool can provide a space for students and teachers to share knowledge and experiences related to teaching and learning.

Home Based Training: Main Strategy in Community Based Rehabilitation in Iran

Directory of Open Access Journals (Sweden)

Peiman Salamati

2006-10-01

Full Text Available Objective: Study of effectiveness of “home based training” in community based rehabilitation program on disabled people, under supervised of 21 pilot cities health and medical networks, who were trained and evaluated at the end of the course. Materials & Methods: In a cross-sectional study, 614 disabled people who had participated in “home based training” were selected with stratified random sampling method. They were evaluated according to function progress level variables by community based rehabilitation programme experts. Age, sex, disability groups, employment state and teacher’s relation variables were studied from their files and recording datas. Statistical analysis was performed with Chi-square test. Results: There was a relationship between age group and disability group with functional progress level (P = 0.014 & P <0.001. Low age groups, visional disabled group, epileptic patients and individuals with learning problems had the best results. High age groups, mixed disability group and individuals with verbal and hearing problems had the least results. There was a relationship between teacher’s relation with progress or nonprogress state (P = 0.038. Individuals that they were own teachers had the best results and individuals with teachers other than first or second relation or health worker had the least results. Conclusion: Home based training in community based rehabilitation programme is an effective method for improving disabled people in some selected groups.

How evidence-based are the recommendations in evidence-based guidelines?

Directory of Open Access Journals (Sweden)

Finlay A McAlister

2007-08-01

Full Text Available BACKGROUND: Treatment recommendations for the same condition from different guideline bodies often disagree, even when the same randomized controlled trial (RCT evidence is cited. Guideline appraisal tools focus on methodology and quality of reporting, but not on the nature of the supporting evidence. This study was done to evaluate the quality of the evidence (based on consideration of its internal validity, clinical relevance, and applicability underlying therapy recommendations in evidence-based clinical practice guidelines. METHODS AND FINDINGS: A cross-sectional analysis of cardiovascular risk management recommendations was performed for three different conditions (diabetes mellitus, dyslipidemia, and hypertension from three pan-national guideline panels (from the United States, Canada, and Europe. Of the 338 treatment recommendations in these nine guidelines, 231 (68% cited RCT evidence but only 105 (45% of these RCT-based recommendations were based on high-quality evidence. RCT-based evidence was downgraded most often because of reservations about the applicability of the RCT to the populations specified in the guideline recommendation (64/126 cases, 51% or because the RCT reported surrogate outcomes (59/126 cases, 47%. CONCLUSIONS: The results of internally valid RCTs may not be applicable to the populations, interventions, or outcomes specified in a guideline recommendation and therefore should not always be assumed to provide high-quality evidence for therapy recommendations.

Microfluidic paper-based biomolecule preconcentrator based on ion concentration polarization.

Science.gov (United States)

Han, Sung Il; Hwang, Kyo Seon; Kwak, Rhokyun; Lee, Jeong Hoon

2016-06-21

Microfluidic paper-based analytical devices (μPADs) for molecular detection have great potential in the field of point-of-care diagnostics. Currently, a critical problem being faced by μPADs is improving their detection sensitivity. Various preconcentration processes have been developed, but they still have complicated structures and fabrication processes to integrate into μPADs. To address this issue, we have developed a novel paper-based preconcentrator utilizing ion concentration polarization (ICP) with minimal addition on lateral-flow paper. The cation selective membrane (i.e., Nafion) is patterned on adhesive tape, and this tape is then attached to paper-based channels. When an electric field is applied across the Nafion, ICP is initiated to preconcentrate the biomolecules in the paper channel. Departing from previous paper-based preconcentrators, we maintain steady lateral fluid flow with the separated Nafion layer; as a result, fluorescent dyes and proteins (FITC-albumin and bovine serum albumin) are continuously delivered to the preconcentration zone, achieving high preconcentration performance up to 1000-fold. In addition, we demonstrate that the Nafion-patterned tape can be integrated with various geometries (multiplexed preconcentrator) and platforms (string and polymer microfluidic channel). This work would facilitate integration of various ICP devices, including preconcentrators, pH/concentration modulators, and micro mixers, with steady lateral flows in paper-based platforms.

Jobs to Manufacturing Careers: Work-Based Courses. Work-Based Learning in Action

Science.gov (United States)

Kobes, Deborah

2016-01-01

This case study, one of a series of publications exploring effective and inclusive models of work-based learning, finds that work-based courses bring college to the production line by using the job as a learning lab. Work-based courses are an innovative way to give incumbent workers access to community college credits and degrees. They are…

Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments

Directory of Open Access Journals (Sweden)

Tcherepanov Vasily

2004-07-01

Full Text Available Abstract Background With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than gene content because two strains of an organism may share the same set of predicted genes but still differ in their pathogenicity profiles. For example, detailed comparison of multiple isolates of the smallpox virus genome (each approximately 200 kb, with 200 genes is not feasible without new bioinformatics tools. Results A software package, Base-By-Base, has been developed that provides visualization tools to enable researchers to 1 rapidly identify and correct alignment errors in large, multiple genome alignments; and 2 generate tabular and graphical output of differences between the genomes at the nucleotide level. Base-By-Base uses detailed annotation information about the aligned genomes and can list each predicted gene with nucleotide differences, display whether variations occur within promoter regions or coding regions and whether these changes result in amino acid substitutions. Base-By-Base can connect to our mySQL database (Virus Orthologous Clusters; VOCs to retrieve detailed annotation information about the aligned genomes or use information from text files. Conclusion Base-By-Base enables users to quickly and easily compare large viral genomes; it highlights small differences that may be responsible for important phenotypic differences such as virulence. It is available via the Internet using Java Web Start and runs on Macintosh, PC and Linux operating systems with the Java 1.4 virtual machine.

Demographic-Based Content Analysis of Web-Based Health-Related Social Media.

Science.gov (United States)

Sadah, Shouq A; Shahbazi, Moloud; Wiley, Matthew T; Hristidis, Vagelis

2016-06-13

An increasing number of patients from diverse demographic groups share and search for health-related information on Web-based social media. However, little is known about the content of the posted information with respect to the users' demographics. The aims of this study were to analyze the content of Web-based health-related social media based on users' demographics to identify which health topics are discussed in which social media by which demographic groups and to help guide educational and research activities. We analyze 3 different types of health-related social media: (1) general Web-based social networks Twitter and Google+; (2) drug review websites; and (3) health Web forums, with a total of about 6 million users and 20 million posts. We analyzed the content of these posts based on the demographic group of their authors, in terms of sentiment and emotion, top distinctive terms, and top medical concepts. The results of this study are: (1) Pregnancy is the dominant topic for female users in drug review websites and health Web forums, whereas for male users, it is cardiac problems, HIV, and back pain, but this is not the case for Twitter; (2) younger users (0-17 years) mainly talk about attention-deficit hyperactivity disorder (ADHD) and depression-related drugs, users aged 35-44 years discuss about multiple sclerosis (MS) drugs, and middle-aged users (45-64 years) talk about alcohol and smoking; (3) users from the Northeast United States talk about physical disorders, whereas users from the West United States talk about mental disorders and addictive behaviors; (4) Users with higher writing level express less anger in their posts. We studied the popular topics and the sentiment based on users' demographics in Web-based health-related social media. Our results provide valuable information, which can help create targeted and effective educational campaigns and guide experts to reach the right users on Web-based social chatter.

Enriched Title-Based Keyword Index Generation Using dBase II.

Science.gov (United States)

Rajendran, P. P.

1986-01-01

Describes the use of a database management system (DBMS)--dBaseII--to create an enriched title-based keyword index for a collection of news items at the Renewable Energy Resources Information Center of the Asian Institute of Technology. The use of DBMSs in libraries in developing countries is emphasized. (Author/LRW)

Workplace Based Assessment in Psychiatry

Directory of Open Access Journals (Sweden)

Ayse Devrim Basterzi

2009-11-01

Full Text Available Workplace based assessment refers to the assessment of working practices based on what doctors actually do in the workplace, and is predominantly carried out in the workplace itself. Assessment drives learning and it is therefore essential that workplace-based assessment focuses on important attributes rather than what is easiest to assess. Workplacebased assessment is usually competency based. Workplace based assesments may well facilitate and enhance various aspects of educational supervisions, including its structure, frequency and duration etc. The structure and content of workplace based assesments should be monitored to ensure that its benefits are maximised by remaining tailored to individual trainees' needs. Workplace based assesment should be used for formative and summative assessments. Several formative assessment methods have been developed for use in the workplace such as mini clinical evaluation exercise (mini-cex, evidence based journal club assesment and case based discussion, multi source feedback etc. This review discusses the need of workplace based assesments in psychiatry graduate education and introduces some of the work place based assesment methods.

Proximity-Based Asynchronous Messaging Platform for Location-Based Internet of Things Service

Directory of Open Access Journals (Sweden)

Hyeong gon Jo

2016-07-01

Full Text Available The Internet of Things (IoT opens up tremendous opportunities to provide location-based applications. However, despite the services around a user being physically adjacent, common IoT platforms use a centralized structure, like a cloud-computing architecture, which transfers large amounts of data to a central server. This raises problems, such as traffic concentration, long service latency, and high communication cost. In this paper, we propose a physical distance-based asynchronous messaging platform that specializes in processing personalized data and location-based messages. The proposed system disperses traffic using a location-based message-delivery protocol, and has high stability.

Design-Based Research

DEFF Research Database (Denmark)

Gynther, Karsten; Christensen, Ove; Petersen, Trine Brun

2012-01-01

I denne artikel introduceres Design Based Research for første gang på dansk i et videnskabeligt tidsskrift. Artiklen præsenterer de grundlæggende antagelser, som ligger til grund for Design Based Research-traditionen, og artiklen diskuterer de principper, som ligger til grund for gennemførelse af...... et DBR-forskningsprojekt. Med udgangspunkt i forsknings- og udviklingsprojektet ELYK: E-læring, Yderområder og Klyngedannelse, præsenteres den innovationsmodel, som projektet har udviklet med udgangspunkt i Design Based Research traditionen. ELYKs DBR innovationsmodel har vist sig effektiv i forhold...

Memory-Based Shallow Parsing

NARCIS (Netherlands)

Tjong Kim Sang, E.F.

2002-01-01

We present memory-based learning approaches to shallow parsing and apply these to five tasks: base noun phrase identification, arbitrary base phrase recognition, clause detection, noun phrase parsing and full parsing. We use feature selection techniques and system combination methods for improving

‘"Education-based Research"

DEFF Research Database (Denmark)

Degn Johansson, Troels

This paper lays out a concept of education-based research-the production of research knowledge within the framework of tertiary design education-as an integration of problem-based learning and research-based education. This leads to a critique of reflective practice as the primary way to facilitate...... learning at this level, a discussion of the nature of design problems in the instrumentalist tradition, and some suggestions as to how design studies curricula may facilitate education-based research....

Memory-Based Shallow Parsing

OpenAIRE

Sang, Erik F. Tjong Kim

2002-01-01

We present memory-based learning approaches to shallow parsing and apply these to five tasks: base noun phrase identification, arbitrary base phrase recognition, clause detection, noun phrase parsing and full parsing. We use feature selection techniques and system combination methods for improving the performance of the memory-based learner. Our approach is evaluated on standard data sets and the results are compared with that of other systems. This reveals that our approach works well for ba...

Changing from a Rules-based to a Principles-based Accounting Logic: A Review

Directory of Open Access Journals (Sweden)

Marta Silva Guerreiro

2014-06-01

Full Text Available We explore influences on unlisted companies when Portugal moved from a code law, rules-based accounting system, to a principles-based accounting system of adapted International Financial Reporting Standards (IFRS. Institutionalisation of the new principles-based system was generally facilitated by a socio-economic and political context that increasingly supported IFRS logic. This helped central actors gain political opportunity, mobilise important allies, and accommodate major protagonists. The preparedness of unlisted companies to adopt the new IFRS-based accounting system voluntarily was explained by their desire to maintain social legitimacy. However, it was affected negatively by the embeddedness of rule-based practices in the ‘old’ prevailing institutional logic.

Constructing regional advantage: platform policies based on related variety and differentiated knowledge bases.

NARCIS (Netherlands)

Asheim, B.T.; Boschma, R.A.; Cooke, P.

2011-01-01

Constructing regional advantage: platform policies based on related variety and differentiated knowledge bases, Regional Studies. This paper presents a regional innovation policy model based on the idea of constructing regional advantage. This policy model brings together concepts like related

An Intelligent Fleet Condition-Based Maintenance Decision Making Method Based on Multi-Agent

OpenAIRE

Bo Sun; Qiang Feng; Songjie Li

2012-01-01

According to the demand for condition-based maintenance online decision making among a mission oriented fleet, an intelligent maintenance decision making method based on Multi-agent and heuristic rules is proposed. The process of condition-based maintenance within an aircraft fleet (each containing one or more Line Replaceable Modules) based on multiple maintenance thresholds is analyzed. Then the process is abstracted into a Multi-Agent Model, a 2-layer model structure containing host negoti...

The ground based plan

International Nuclear Information System (INIS)

1989-01-01

The paper presents a report of ''The Ground Based Plan'' of the United Kingdom Science and Engineering Research Council. The ground based plan is a plan for research in astronomy and planetary science by ground based techniques. The contents of the report contains a description of:- the scientific objectives and technical requirements (the basis for the Plan), the present organisation and funding for the ground based programme, the Plan, the main scientific features and the further objectives of the Plan. (U.K.)

Content-Based Image Retrieval Based on Electromagnetism-Like Mechanism

Directory of Open Access Journals (Sweden)

Hamid A. Jalab

2013-01-01

Full Text Available Recently, many researchers in the field of automatic content-based image retrieval have devoted a remarkable amount of research looking for methods to retrieve the best relevant images to the query image. This paper presents a novel algorithm for increasing the precision in content-based image retrieval based on electromagnetism optimization technique. The electromagnetism optimization is a nature-inspired technique that follows the collective attraction-repulsion mechanism by considering each image as an electrical charge. The algorithm is composed of two phases: fitness function measurement and electromagnetism optimization technique. It is implemented on a database with 8,000 images spread across 80 classes with 100 images in each class. Eight thousand queries are fired on the database, and the overall average precision is computed. Experimental results of the proposed approach have shown significant improvement in the retrieval performance in regard to precision.

Risk based modelling

International Nuclear Information System (INIS)

Chapman, O.J.V.; Baker, A.E.

1993-01-01

Risk based analysis is a tool becoming available to both engineers and managers to aid decision making concerning plant matters such as In-Service Inspection (ISI). In order to develop a risk based method, some form of Structural Reliability Risk Assessment (SRRA) needs to be performed to provide a probability of failure ranking for all sites around the plant. A Probabilistic Risk Assessment (PRA) can then be carried out to combine these possible events with the capability of plant safety systems and procedures, to establish the consequences of failure for the sites. In this way the probability of failures are converted into a risk based ranking which can be used to assist the process of deciding which sites should be included in an ISI programme. This paper reviews the technique and typical results of a risk based ranking assessment carried out for nuclear power plant pipework. (author)

Synthesis and photoluminescence properties of novel Schiff base type polymer-rare earth complexes containing furfural-based bidentate Schiff base ligands

Science.gov (United States)

Gao, Baojiao; Zhang, Dandan; Li, Yanbin

2018-03-01

Luminescent polymer-rare earth complexes are an important class of photoluminescence and electroluminescence materials. Via molecular design, two furfural-based bidentate Schiff base ligands, furfural-aniline (FA) type ligand and furfural-cyclohexylamine (FC) type ligand, were bonded on the side chains of polysulfone (PSF), respectively, forming two functionalized macromolecules, PSF-FA and PSF-FC. And then through respective coordination reactions of the two functionalized macromolecules with Eu(Ⅲ) ion and Tb(Ⅲ) ion, novel luminescent binary and ternary (with 1,10-phenanthroline as the second ligand) polymer-rare earth complexes were synthesized. For these complexes, on basis of the characterization of their chemical structures, they photoluminescence properties were main researched, and the relationship between their luminescent properties and structures was explored. The experimental results show that the complexes coming from PSF-FA and Eu(Ⅲ) ion including binary and ternary complexes emit strong red luminescence, indicating that the bonded bidentate Schiff base ligand FA can sensitize the fluorescence emission of Eu(III) ion. While the complexes coming from PSF-FC and Tb(Ⅲ) ion produce green luminescence, displaying that the bonded bidentate Schiff base ligand FC can sensitize the fluorescence emission of Tb(Ⅲ) ion. The fluorescence emission intensities of the ternary complexes were stronger than that of binary complexes, reflecting the important effect of the second ligand. The fluorescence emission of the solid film of complexes is much stronger than that of the solutions of complexes. Besides, by comparison, it is found that the furfural (as a heteroaromatic compound)-based Schiff base type polymer-rare earth complexes have stronger fluorescence emission and higher energy transfer efficiency than salicylaldehyde (as a common aromatic compound)-based Schiff base type polymer-rare earth complexes.

Review of performance-based incentives in community-based family planning programmes

Science.gov (United States)

Bellows, Nicole M; Askew, Ian; Bellows, Benjamin

2015-01-01

Background One strategy for improving family planning (FP) uptake at the community level is the use of performance-based incentives (PBIs), which offer community distributors financial incentives to recruit more users of FP. This article examines the use of PBIs in community-based FP programmes via a literature search of the peer-reviewed and grey literature conducted in April 2013. Results A total of 28 community-based FP programmes in 21 countries were identified as having used PBIs. The most common approach was a sales commission model where distributors received commission for FP products sold, while a referral payment model for long-term methods was also used extensively. Six evaluations were identified that specifically examined the impact of the PBI in community-based FP programmes. Overall, the results of the evaluations are mixed and more research is needed; however, the findings suggest that easy-to-understand PBIs can be successful in increasing the use of FP at the community level. Conclusion For future use of PBIs in community-based FP programmes it is important to consider the ethics of incentivising FP and ensuring that PBIs are non-coercive and choice-enhancing. PMID:25037703

Unifying Model-Based and Reactive Programming within a Model-Based Executive

Science.gov (United States)

Williams, Brian C.; Gupta, Vineet; Norvig, Peter (Technical Monitor)

1999-01-01

Real-time, model-based, deduction has recently emerged as a vital component in AI's tool box for developing highly autonomous reactive systems. Yet one of the current hurdles towards developing model-based reactive systems is the number of methods simultaneously employed, and their corresponding melange of programming and modeling languages. This paper offers an important step towards unification. We introduce RMPL, a rich modeling language that combines probabilistic, constraint-based modeling with reactive programming constructs, while offering a simple semantics in terms of hidden state Markov processes. We introduce probabilistic, hierarchical constraint automata (PHCA), which allow Markov processes to be expressed in a compact representation that preserves the modularity of RMPL programs. Finally, a model-based executive, called Reactive Burton is described that exploits this compact encoding to perform efficIent simulation, belief state update and control sequence generation.

Problem based Learning versus Design Thinking in Team based Project work

DEFF Research Database (Denmark)

Denise J. Stokholm, Marianne

2014-01-01

project based learning issues, which has caused a need to describe and compare the two models; in specific the understandings, approaches and organization of learning in project work. The PBL model viewing the process as 3 separate project stages including; problem analysis, problem solving and project......All educations at Aalborg University has since 1974 been rooted in Problem Based Learning (PBL). In 1999 a new education in Industrial design was set up, introducing Design Based Learning (DBL). Even though the two approaches have a lot in common they also hold different understandings of core...... report, with focus on problem solving through analysis. Design Based Learning viewing the process as series of integrated design spaces including; alignment, research, mission, vision, concept, product and process report, with focus on innovative ideation though integration. There is a need of renewing...

Measuring Costs to Community-Based Agencies for Implementation of an Evidence-Based Practice.

Science.gov (United States)

Lang, Jason M; Connell, Christian M

2017-01-01

Healthcare reform has led to an increase in dissemination of evidence-based practices. Cost is frequently cited as a significant yet rarely studied barrier to dissemination of evidence-based practices and the associated improvements in quality of care. This study describes an approach to measuring the incremental, unreimbursed costs in staff time and direct costs to community-based clinics implementing an evidence-based practice through participating in a learning collaborative. Initial implementation costs exceeding those for providing "treatment as usual" were collected for ten clinics implementing trauma-focused cognitive behavioral therapy through participation in 10-month learning collaboratives. Incremental implementation costs of these ten community-based clinic teams averaged the equivalent of US$89,575 (US$ 2012). The most costly activities were training, supervision, preparation time, and implementation team meetings. Recommendations are made for further research on implementation costs, dissemination of evidence-based practices, and implications for researchers and policy makers.

Ratio-based vs. model-based methods to correct for urinary creatinine concentrations.

Science.gov (United States)

Jain, Ram B

2016-08-01

Creatinine-corrected urinary analyte concentration is usually computed as the ratio of the observed level of analyte concentration divided by the observed level of the urinary creatinine concentration (UCR). This ratio-based method is flawed since it implicitly assumes that hydration is the only factor that affects urinary creatinine concentrations. On the contrary, it has been shown in the literature, that age, gender, race/ethnicity, and other factors also affect UCR. Consequently, an optimal method to correct for UCR should correct for hydration as well as other factors like age, gender, and race/ethnicity that affect UCR. Model-based creatinine correction in which observed UCRs are used as an independent variable in regression models has been proposed. This study was conducted to evaluate the performance of ratio-based and model-based creatinine correction methods when the effects of gender, age, and race/ethnicity are evaluated one factor at a time for selected urinary analytes and metabolites. It was observed that ratio-based method leads to statistically significant pairwise differences, for example, between males and females or between non-Hispanic whites (NHW) and non-Hispanic blacks (NHB), more often than the model-based method. However, depending upon the analyte of interest, the reverse is also possible. The estimated ratios of geometric means (GM), for example, male to female or NHW to NHB, were also compared for the two methods. When estimated UCRs were higher for the group (for example, males) in the numerator of this ratio, these ratios were higher for the model-based method, for example, male to female ratio of GMs. When estimated UCR were lower for the group (for example, NHW) in the numerator of this ratio, these ratios were higher for the ratio-based method, for example, NHW to NHB ratio of GMs. Model-based method is the method of choice if all factors that affect UCR are to be accounted for.

Capability-based computer systems

CERN Document Server

Levy, Henry M

2014-01-01

Capability-Based Computer Systems focuses on computer programs and their capabilities. The text first elaborates capability- and object-based system concepts, including capability-based systems, object-based approach, and summary. The book then describes early descriptor architectures and explains the Burroughs B5000, Rice University Computer, and Basic Language Machine. The text also focuses on early capability architectures. Dennis and Van Horn's Supervisor; CAL-TSS System; MIT PDP-1 Timesharing System; and Chicago Magic Number Machine are discussed. The book then describes Plessey System 25

Comparison of Subset-Based Local and Finite Element-Based Global Digital Image Correlation

KAUST Repository

Pan, Bing; Wang, B.; Lubineau, Gilles; Moussawi, Ali

2015-01-01

Digital image correlation (DIC) techniques require an image matching algorithm to register the same physical points represented in different images. Subset-based local DIC and finite element-based (FE-based) global DIC are the two primary image matching methods that have been extensively investigated and regularly used in the field of experimental mechanics. Due to its straightforward implementation and high efficiency, subset-based local DIC has been used in almost all commercial DIC packages. However, it is argued by some researchers that FE-based global DIC offers better accuracy because of the enforced continuity between element nodes. We propose a detailed performance comparison between these different DIC algorithms both in terms of measurement accuracy and computational efficiency. Then, by measuring displacements of the same calculation points using the same calculation algorithms (e.g., correlation criterion, initial guess estimation, subpixel interpolation, optimization algorithm and convergence conditions) and identical calculation parameters (e.g., subset or element size), the performances of subset-based local DIC and two FE-based global DIC approaches are carefully compared in terms of measurement error and computational efficiency using both numerical tests and real experiments. A detailed examination of the experimental results reveals that, when subset (element) size is not very small and the local deformation within a subset (element) can be well approximated by the shape function used, standard subset-based local DIC approach not only provides better results in measured displacements, but also demonstrates much higher computation efficiency. However, several special merits of FE-based global DIC approaches are indicated.

Comparison of Subset-Based Local and Finite Element-Based Global Digital Image Correlation

KAUST Repository

Pan, Bing

2015-02-12

Digital image correlation (DIC) techniques require an image matching algorithm to register the same physical points represented in different images. Subset-based local DIC and finite element-based (FE-based) global DIC are the two primary image matching methods that have been extensively investigated and regularly used in the field of experimental mechanics. Due to its straightforward implementation and high efficiency, subset-based local DIC has been used in almost all commercial DIC packages. However, it is argued by some researchers that FE-based global DIC offers better accuracy because of the enforced continuity between element nodes. We propose a detailed performance comparison between these different DIC algorithms both in terms of measurement accuracy and computational efficiency. Then, by measuring displacements of the same calculation points using the same calculation algorithms (e.g., correlation criterion, initial guess estimation, subpixel interpolation, optimization algorithm and convergence conditions) and identical calculation parameters (e.g., subset or element size), the performances of subset-based local DIC and two FE-based global DIC approaches are carefully compared in terms of measurement error and computational efficiency using both numerical tests and real experiments. A detailed examination of the experimental results reveals that, when subset (element) size is not very small and the local deformation within a subset (element) can be well approximated by the shape function used, standard subset-based local DIC approach not only provides better results in measured displacements, but also demonstrates much higher computation efficiency. However, several special merits of FE-based global DIC approaches are indicated.

Influencing factors for condition-based maintenance in railway tracks using knowledge-based approach

NARCIS (Netherlands)

Jamshidi, A.; Hajizadeh, S.; Naeimi, M.; Nunez Vicencio, Alfredo; Li, Z.

2017-01-01

In this paper, we present a condition-based maintenance decision method using
knowledge-based approach for rail surface defects. A railway track may contain a considerable number of surface defects which influence track maintenance decisions. The proposed method is based on two sets of

A comparison of arc-based and static mini-multileaf collimator-based radiosurgery treatment plans

International Nuclear Information System (INIS)

Kubo, Hideo Dale; Pappas, Conrad T.E.; Wilder, Richard B.

1997-01-01

Background: The purpose of this study is to compare arc-based and mini-multileaf collimator (mMLC)-based radiosurgery treatment plans using isodose distributions and dose-volume histograms. Methods: Of 11 patients who underwent conventional arc-based radiosurgery for intracranial malignancies, four were treated with one isocenter, four were treated with two isocenters and three were treated with three isocenters. The same cases were re-planned using a test version of mMLC-based radiosurgery software for multiple static non-coplanar fields. Results and conclusion: For non-spherical targets, treatment planning is relatively intuitive with mMLC-based radiosurgery, reducing the amount of time required for planning. Moreover, a lower dose of radiation is delivered to normal tissue with mMLC-based radiosurgery than with arc-based radiosurgery, which theoretically should lead to a reduced risk of complications

Performance-Based Funding Brief

Science.gov (United States)

Washington Higher Education Coordinating Board, 2011

2011-01-01

A number of states have made progress in implementing performance-based funding (PFB) and accountability. This policy brief summarizes main features of performance-based funding systems in three states: Tennessee, Ohio, and Indiana. The brief also identifies key issues that states considering performance-based funding must address, as well as…

Office-based anaesthesia

African Journals Online (AJOL)

infection, and consistency in nursing personnel. In the USA 17 -. 24% of all elective ambulatory surgery is ... knowledge base or personality to deal with the OBA environment. Compared with hospitals, office-based facilities currently ... disease or major cardiovascular risk factors). Intravenous access via a flexible cannula is.

Conceptual Pathway Querying of Natural Logic Knowledge Bases from Text Bases

DEFF Research Database (Denmark)

Andreasen, Troels; Bulskov, Henrik; Nilsson, Jørgen Fischer

2013-01-01

language than predicate logic. Natural logic accommodates a variety of scientific parlance, ontologies and domain models. It also supports a semantic net or graph view of the knowledge base. This admits computation of relationships between concepts simultaneously through pathfinding in the knowledge base...

Tracing the Base: A Topographic Test for Collusive Basing-Point Pricing

NARCIS (Netherlands)

Bos, Iwan; Schinkel, Maarten Pieter

2009-01-01

Basing-point pricing is known to have been abused by geographically dispersed firms in order to eliminate competition on transportation costs. This paper develops a topographic test for collusive basing-point pricing. The method uses transaction data (prices, quantities) and customer project site

Tracing the base: A topographic test for collusive basing-point pricing

NARCIS (Netherlands)

Bos, I.; Schinkel, M.P.

2008-01-01

Basing-point pricing is known to have been abused by geographically dispersed firms in order to eliminate competition on transportation costs. This paper develops a topographic test for collusive basing-point pricing. The method uses transaction data (prices, quantities) and customer project site

Moving from Rule-based to Principle-based in Public Sector: Preparers' Perspective

OpenAIRE

Roshayani Arshad; Normah Omar; Siti Fatimah Awang

2013-01-01

The move from cash accounting to accrual accounting, or rule-based to principle-based accounting, by many governments is part of an ongoing efforts in promoting a more business-like and performance-focused public sector. Using questionnaire responses from preparers of financial statements of public universities in Malaysia, this study examines the implementation challenges and benefits of principle-based accounting. Results from these responses suggest that most respondents perceived signific...

Thulium-based bulk metallic glass

International Nuclear Information System (INIS)

Yu, H. B.; Yu, P.; Wang, W. H.; Bai, H. Y.

2008-01-01

We report the formation and properties of a thulium-based bulk metallic glass (BMG). Compared with other known rare-earth (RE) based BMGs, Tm-based BMGs show features of excellent glass formation ability, considerable higher elastic modulus, smaller Poisson's ratio, high mechanical strength, and intrinsic brittleness. The reasons for the different properties between the Tm-based and other RE-based BMGs are discussed. It is expected that the Tm-based glasses with the unique properties are appropriate candidates for studying some important issues in BMGs

Feature-based and object-based attention orientation during short-term memory maintenance.

Science.gov (United States)

Ku, Yixuan

2015-12-01

Top-down attention biases the short-term memory (STM) processing at multiple stages. Orienting attention during the maintenance period of STM by a retrospective cue (retro-cue) strengthens the representation of the cued item and improves the subsequent STM performance. In a recent article, Backer et al. (Backer KC, Binns MA, Alain C. J Neurosci 35: 1307-1318, 2015) extended these findings from the visual to the auditory domain and combined electroencephalography to dissociate neural mechanisms underlying feature-based and object-based attention orientation. Both event-related potentials and neural oscillations explained the behavioral benefits of retro-cues and favored the theory that feature-based and object-based attention orientation were independent. Copyright © 2015 the American Physiological Society.

THE DESIGN OF KNOWLEDGE BASE FOR SURFACE RELATIONS BASED PART RECOGNITION APPROACH

Directory of Open Access Journals (Sweden)

Adem ÇİÇEK

2007-01-01

Full Text Available In this study, a new knowledge base for an expert system used in part recognition algorithm has been designed. Parts are recognized by the computer program by comparing face adjacency relations and attributes belonging to each part represented in the rules in the knowledge base developed with face adjacency relations and attributes generated from STEP file of the part. Besides, rule writing process has been quite simplified by generating the rules represented in the knowledge base with an automatic rule writing module developed within the system. With the knowledge base and automatic rule writing module used in the part recognition system, simple, intermediate and complex parts can be recognized by a part recognition program.

Game-based versus traditional case-based learning: comparing effectiveness in stroke continuing medical education.

Science.gov (United States)

Telner, Deanna; Bujas-Bobanovic, Maja; Chan, David; Chester, Bob; Marlow, Bernard; Meuser, James; Rothman, Arthur; Harvey, Bart

2010-09-01

To evaluate family physicians' enjoyment of and knowledge gained from game-based learning, compared with traditional case-based learning, in a continuing medical education (CME) event on stroke prevention and management. An equivalence trial to determine if game-based learning was as effective as case-based learning in terms of attained knowledge levels. Game questions and small group cases were developed. Participants were randomized to either a game-based or a case-based group and took part in the event. Ontario provincial family medicine conference. Thirty-two family physicians and 3 senior family medicine residents attending the conference. Participation in either a game-based or a case-based CME learning group. Scores on 40-item immediate and 3-month posttests of knowledge and a satisfaction survey. Results from knowledge testing immediately after the event and 3 months later showed no significant difference in scoring between groups. Participants in the game-based group reported higher levels of satisfaction with the learning experience. Games provide a novel way of organizing CME events. They might provide more group interaction and discussion, as well as improve recruitment to CME events. They might also provide a forum for interdisciplinary CME. Using games in future CME events appears to be a promising approach to facilitate participant learning.

The roles of constraint-based and dedication-based influences on user's continued online shopping behavior.

Science.gov (United States)

Chang, Su-Chao; Chou, Chi-Min

2012-11-01

The objective of this study was to determine empirically the role of constraint-based and dedication-based influences as drivers of the intention to continue using online shopping websites. Constraint-based influences consist of two variables: trust and perceived switching costs. Dedication-based influences consist of three variables: satisfaction, perceived usefulness, and trust. The current results indicate that both constraint-based and dedication-based influences are important drivers of the intention to continue using online shopping websites. The data also shows that trust has the strongest total effect on online shoppers' intention to continue using online shopping websites. In addition, the results indicate that the antecedents of constraint-based influences, technical bonds (e.g., perceived operational competence and perceived website interactivity) and social bonds (e.g., perceived relationship investment, community building, and intimacy) have indirect positive effects on the intention to continue using online shopping websites. Based on these findings, this research suggests that online shopping websites should build constraint-based and dedication-based influences to enhance user's continued online shopping behaviors simultaneously.

Content-based intermedia synchronization

Science.gov (United States)

Oh, Dong-Young; Sampath-Kumar, Srihari; Rangan, P. Venkat

1995-03-01

Inter-media synchronization methods developed until now have been based on syntactic timestamping of video frames and audio samples. These methods are not fully appropriate for the synchronization of multimedia objects which may have to be accessed individually by their contents, e.g. content-base data retrieval. We propose a content-based multimedia synchronization scheme in which a media stream is viewed as hierarchial composition of smaller objects which are logically structured based on the contents, and the synchronization is achieved by deriving temporal relations among logical units of media object. content-based synchronization offers several advantages such as, elimination of the need for time stamping, freedom from limitations of jitter, synchronization of independently captured media objects in video editing, and compensation for inherent asynchronies in capture times of video and audio.

Secure base stations

NARCIS (Netherlands)

Bosch, Peter; Brusilovsky, Alec; McLellan, Rae; Mullender, Sape J.; Polakos, Paul

2009-01-01

With the introduction of the third generation (3G) Universal Mobile Telecommunications System (UMTS) base station router (BSR) and fourth generation (4G) base stations, such as the 3rd Generation Partnership Project (3GPP) Long Term Evolution (LTE) Evolved Node B (eNB), it has become important to

Zero-Based Budgeting.

Science.gov (United States)

Wichowski, Chester

1979-01-01

The zero-based budgeting approach is designed to achieve the greatest benefit with the fewest undesirable consequences. Seven basic steps make up the zero-based decision-making process: (1) identifying program goals, (2) classifying goals, (3) identifying resources, (4) reviewing consequences, (5) developing decision packages, (6) implementing a…

Combining Correlation-Based and Reward-Based Learning in Neural Control for Policy Improvement

DEFF Research Database (Denmark)

Manoonpong, Poramate; Kolodziejski, Christoph; Wörgötter, Florentin

2013-01-01

Classical conditioning (conventionally modeled as correlation-based learning) and operant conditioning (conventionally modeled as reinforcement learning or reward-based learning) have been found in biological systems. Evidence shows that these two mechanisms strongly involve learning about...... associations. Based on these biological findings, we propose a new learning model to achieve successful control policies for artificial systems. This model combines correlation-based learning using input correlation learning (ICO learning) and reward-based learning using continuous actor–critic reinforcement...... learning (RL), thereby working as a dual learner system. The model performance is evaluated by simulations of a cart-pole system as a dynamic motion control problem and a mobile robot system as a goal-directed behavior control problem. Results show that the model can strongly improve pole balancing control...

Culture and group-based emotions? : Could group-based emotions be dialectical

NARCIS (Netherlands)

Lu, M.; Hamamura, T.; Doosje, B.; Suzuki, S.; Takemura, K.

2016-01-01

Group-based emotions are experienced when individuals are engaged in emotion-provoking events that implicate the in-group. This research examines the complexity of group-based emotions, specifically a concurrence of positive and negative emotions, focusing on the role of dialecticism, or a set of

Methods for Model-Based Reasoning within Agent-Based Ambient Intelligence Applications

NARCIS (Netherlands)

Bosse, T.; Both, F.; Gerritsen, C.; Hoogendoorn, M.; Treur, J.

2012-01-01

Within agent-based Ambient Intelligence applications agents react to humans based on information obtained by sensoring and their knowledge about human functioning. Appropriate types of reactions depend on the extent to which an agent understands the human and is able to interpret the available

Benefit-based tree valuation

Science.gov (United States)

E.G. McPherson

2007-01-01

Benefit-based tree valuation provides alternative estimates of the fair and reasonable value of trees while illustrating the relative contribution of different benefit types. This study compared estimates of tree value obtained using cost- and benefit-based approaches. The cost-based approach used the Council of Landscape and Tree Appraisers trunk formula method, and...

Electrophysiological correlates of strategic monitoring in event-based and time-based prospective memory.

Directory of Open Access Journals (Sweden)

Giorgia Cona

Full Text Available Prospective memory (PM is the ability to remember to accomplish an action when a particular event occurs (i.e., event-based PM, or at a specific time (i.e., time-based PM while performing an ongoing activity. Strategic Monitoring is one of the basic cognitive functions supporting PM tasks, and involves two mechanisms: a retrieval mode, which consists of maintaining active the intention in memory; and target checking, engaged for verifying the presence of the PM cue in the environment. The present study is aimed at providing the first evidence of event-related potentials (ERPs associated with time-based PM, and at examining differences and commonalities in the ERPs related to Strategic Monitoring mechanisms between event- and time-based PM tasks.The addition of an event-based or a time-based PM task to an ongoing activity led to a similar sustained positive modulation of the ERPs in the ongoing trials, mainly expressed over prefrontal and frontal regions. This modulation might index the retrieval mode mechanism, similarly engaged in the two PM tasks. On the other hand, two further ERP modulations were shown specifically in an event-based PM task. An increased positivity was shown at 400-600 ms post-stimulus over occipital and parietal regions, and might be related to target checking. Moreover, an early modulation at 130-180 ms post-stimulus seems to reflect the recruitment of attentional resources for being ready to respond to the event-based PM cue. This latter modulation suggests the existence of a third mechanism specific for the event-based PM; that is, the "readiness mode".

Internet-based system for simulation-based medical planning for cardiovascular disease.

Science.gov (United States)

Steele, Brooke N; Draney, Mary T; Ku, Joy P; Taylor, Charles A

2003-06-01

Current practice in vascular surgery utilizes only diagnostic and empirical data to plan treatments, which does not enable quantitative a priori prediction of the outcomes of interventions. We have previously described simulation-based medical planning methods to model blood flow in arteries and plan medical treatments based on physiologic models. An important consideration for the design of these patient-specific modeling systems is the accessibility to physicians with modest computational resources. We describe a simulation-based medical planning environment developed for the World Wide Web (WWW) using the Virtual Reality Modeling Language (VRML) and the Java programming language.

Part-based Pedestrian Detection and Feature-based Tracking for Driver Assistance

DEFF Research Database (Denmark)

Prioletti, Antonio; Møgelmose, Andreas; Grislieri, Paolo

2013-01-01

Detecting pedestrians is still a challenging task for automotive vision systems due to the extreme variability of targets, lighting conditions, occlusion, and high-speed vehicle motion. Much research has been focused on this problem in the last ten years and detectors based on classifiers have...... on a prototype vehicle and offers high performance in terms of several metrics, such as detection rate, false positives per hour, and frame rate. The novelty of this system relies on the combination of a HOG part-based approach, tracking based on a specific optimized feature, and porting on a real prototype....

LDEF materials data bases

Science.gov (United States)

Funk, Joan G.; Strickland, John W.; Davis, John M.

1993-01-01

The Long Duration Exposure Facility (LDEF) and the accompanying experiments were composed of and contained a wide variety of materials representing the largest collection of materials flown in low Earth orbit (LEO) and retrieved for ground based analysis to date. The results and implications of the mechanical, thermal, optical, and electrical data from these materials are the foundation on which future LEO space missions will be built. The LDEF Materials Special Investigation Group (MSIG) has been charged with establishing and developing data bases to document these materials and their performance to assure not only that the data are archived for future generations but also that the data are available to the spacecraft user community in an easily accessed, user-friendly form. This paper discusses the format and content of the three data bases developed or being developed to accomplish this task. The hardware and software requirements for each of these three data bases are discussed along with current availability of the data bases. This paper also serves as a user's guide to the MAPTIS LDEF Materials Data Base.

Data base dictionary for the Oak Ridge Reservation Hydrology and Geology Study Groundwater Data Base

Energy Technology Data Exchange (ETDEWEB)

Thompson, B.K.

1993-04-01

The Oak Ridge Reservation Hydrology and Geology Study (ORRHAGS) Groundwater Data Base has been compiled to consolidate groundwater data from the three US Department of Energy facilities located on the Oak Ridge Reservation: the Oak Ridge K-25 Site, the Oak Ridge National Laboratory, and the Oak Ridge Y-12 Plant. Each of these facilities maintains its own groundwater and well construction data bases. Data were extracted from the existing data bases, converted to a consistent format, and integrated into the ORRHAGS Groundwater Data Base structures. This data base dictionary describes the data contained in the ORRHAGS Groundwater Data Base and contains information on data base structure, conventions, contents, and use.

Chord-based versus voxel-based methods of electron transport in the skeletal tissues

International Nuclear Information System (INIS)

Shah, Amish P.; Jokisch, Derek W.; Rajon, Didier A.; Watchman, Christopher J.; Patton, Phillip W.; Bolch, Wesley E.

2005-01-01

Anatomic models needed for internal dose assessment have traditionally been developed using mathematical surface equations to define organ boundaries, shapes, and their positions within the body. Many researchers, however, are now advocating the use of tomographic models created from segmented patient computed tomography (CT) or magnetic resonance (MR) scans. In the skeleton, however, the tissue structures of the bone trabeculae, marrow cavities, and endosteal layer are exceedingly small and of complex shape, and thus do not lend themselves easily to either stylistic representations or in-vivo CT imaging. Historically, the problem of modeling the skeletal tissues has been addressed through the development of chord-based methods of radiation particle transport, as given by studies at the University of Leeds (Leeds, UK) using a 44-year male subject. We have proposed an alternative approach to skeletal dosimetry in which excised sections of marrow-intact cadaver spongiosa are imaged directly via microCT scanning. The cadaver selected for initial investigation of this technique was a 66-year male subject of nominal body mass index (22.7 kg m -2 ). The objectives of the present study were to compare chord-based versus voxel-based methods of skeletal dosimetry using data from the UF 66-year male subject. Good agreement between chord-based and voxel-based transport was noted for marrow irradiation by either bone surface or bone volume sources up to 500-1000 keV (depending upon the skeletal site). In contrast, chord-based models of electron transport yielded consistently lower values of the self-absorbed fraction to marrow tissues than seen under voxel-based transport at energies above 100 keV, a feature directly attributed to the inability of chord-based models to account for nonlinear electron trajectories. Significant differences were also noted in the dosimetry of the endosteal layer (for all source tissues), with chord-based transport predicting a higher fraction of

Nature-based integration

DEFF Research Database (Denmark)

Pitkänen, Kati; Oratuomi, Joose; Hellgren, Daniela

Increased attention to, and careful planning of the integration of migrants into Nordic societies is ever more important. Nature based integration is a new solution to respond to this need. This report presents the results of a Nordic survey and workshop and illustrates current practices of nature...... based integration by case study descriptions from Denmark, Sweden Norway and Finland. Across Nordic countries several practical projects and initiatives have been launched to promote the benefits of nature in integration and there is also growing academic interest in the topic. Nordic countries have...... the potential of becoming real forerunners in nature based integration even at the global scale....

Application of data base management systems for developing experimental data base using ES computers

International Nuclear Information System (INIS)

Vasil'ev, V.I.; Karpov, V.V.; Mikhajlyuk, D.N.; Ostroumov, Yu.A.; Rumyantsev, A.N.

1987-01-01

Modern data base measurement systems (DBMS) are widely used for development and operation of different data bases by assignment of data processing systems in economy, planning, management. But up today development and operation of data masses with experimental physical data in ES computer has been based mainly on the traditional technology of consequent or index-consequent files. The principal statements of DBMS technology applicability for compiling and operation of data bases with data on physical experiments are formulated based on the analysis of DBMS opportunities. It is shown that application of DBMS allows to essentially reduce general costs of calculational resources for development and operation of data bases and to decrease the scope of stored experimental data when analyzing information content of data

RIM as the data base management system for a material properties data base

Science.gov (United States)

Karr, P. H.; Wilson, D. J.

1984-01-01

Relational Information Management (RIM) was selected as the data base management system for a prototype engineering materials data base. The data base provides a central repository for engineering material properties data, which facilitates their control. Numerous RIM capabilities are exploited to satisfy prototype data base requirements. Numerical, text, tabular, and graphical data and references are being stored for five material types. Data retrieval will be accomplished both interactively and through a FORTRAN interface. The experience gained in creating and exercising the prototype will be used in specifying requirements for a production system.

Multi-scale sustainability assessments for biomass-based and coal-based fuels in China.

Science.gov (United States)

Man, Yi; Xiao, Honghua; Cai, Wei; Yang, Siyu

2017-12-01

Transportation liquid fuels production is heavily depend on oil. In recent years, developing biomass based and coal based fuels are regarded as promising alternatives for non-petroleum based fuels in China. With the rapid growth of constructing and planning b biomass based and coal based fuels production projects, sustainability assessments are needed to simultaneously consider the resource, the economic, and the environmental factors. This paper performs multi-scale analyses on the biomass based and coal based fuels in China. The production cost, life cycle cost, and ecological life cycle cost (ELCC) of these synfuels are investigated to compare their pros to cons and reveal the sustainability. The results show that BTL fuels has high production cost. It lacks of economic attractiveness. However, insignificant resource cost and environmental cost lead to a substantially lower ELCC, which may indicate better ecological sustainability. CTL fuels, on the contrary, is lower in production cost and reliable for economic benefit. But its coal consumption and pollutant emissions are both serious, leading to overwhelming resource cost and environmental cost. A shifting from petroleum to CTL fuels could double the ELCC, posing great threat to the sustainability of the entire fuels industry. Copyright © 2017 Elsevier B.V. All rights reserved.

Hypermedia-Based Problem Based Learning in the Upper Elementary Grades: A Developmental Study.

Science.gov (United States)

Brinkerhoff, Jonathan D.; Glazewski, Krista

This paper describes the application of problem-based learning (PBL) design principles and the inclusion of teacher and study scaffolds to the design and implementation of a hypermedia-based learning unit for the upper elementary/middle school grades. The study examined the following research questions: (1) Does hypermedia-based PBL represent an…

Team-based global organizations

DEFF Research Database (Denmark)

Zander, Lena; Butler, Christina; Mockaitis, Audra

2015-01-01

diversity in enhancing team creativity and performance, and 2) the sharing of knowledge in team-based organizations, while the other two themes address global team leadership: 3) the unprecedented significance of social capital for the success of global team leader roles; and 4) the link between shared......This chapter draws on a panel discussion of the future of global organizing as a team-based organization at EIBA 2014 in Uppsala, Sweden. We began by discussing contemporary developments of hybrid forms of hierarchy and teams-based organizing, but we venture to propose that as organizations become...... characterized by decreased importance of hierarchal structures, more fluidity across borders, even a possible dissolution of firm boundaries, we move towards team-based organizing as an alternative to more traditional forms of hierarchical-based organizing in global firms. To provide input for a discussion...

Competency-Based Assessment for Clinical Supervisors: Design-Based Research on a Web-Delivered Program

Science.gov (United States)

Williams, Lauren Therese; Grealish, Laurie; Jamieson, Maggie

2015-01-01

Background Clinicians need to be supported by universities to use credible and defensible assessment practices during student placements. Web-based delivery of clinical education in student assessment offers professional development regardless of the geographical location of placement sites. Objective This paper explores the potential for a video-based constructivist Web-based program to support site supervisors in their assessments of student dietitians during clinical placements. Methods This project was undertaken as design-based research in two stages. Stage 1 describes the research consultation, development of the prototype, and formative feedback. In Stage 2, the program was pilot-tested and evaluated by a purposeful sample of nine clinical supervisors. Data generated as a result of user participation during the pilot test is reported. Users’ experiences with the program were also explored via interviews (six in a focus group and three individually). The interviews were transcribed verbatim and thematic analysis conducted from a pedagogical perspective using van Manen’s highlighting approach. Results This research succeeded in developing a Web-based program, “Feed our Future”, that increased supervisors’ confidence with their competency-based assessments of students on clinical placements. Three pedagogical themes emerged: constructivist design supports transformative Web-based learning; videos make abstract concepts tangible; and accessibility, usability, and pedagogy are interdependent. Conclusions Web-based programs, such as Feed our Future, offer a viable means for universities to support clinical supervisors in their assessment practices during clinical placements. A design-based research approach offers a practical process for such Web-based tool development, highlighting pedagogical barriers for planning purposes. PMID:25803172

Quality of nursing documentation: Paper-based health records versus electronic-based health records.

Science.gov (United States)

Akhu-Zaheya, Laila; Al-Maaitah, Rowaida; Bany Hani, Salam

2018-02-01

To assess and compare the quality of paper-based and electronic-based health records. The comparison examined three criteria: content, documentation process and structure. Nursing documentation is a significant indicator of the quality of patient care delivery. It can be either paper-based or organised within the system known as the electronic health records. Nursing documentation must be completed at the highest standards, to ensure the safety and quality of healthcare services. However, the evidence is not clear on which one of the two forms of documentation (paper-based versus electronic health records is more qualified. A retrospective, descriptive, comparative design was used to address the study's purposes. A convenient number of patients' records, from two public hospitals, were audited using the Cat-ch-Ing audit instrument. The sample size consisted of 434 records for both paper-based health records and electronic health records from medical and surgical wards. Electronic health records were better than paper-based health records in terms of process and structure. In terms of quantity and quality content, paper-based records were better than electronic health records. The study affirmed the poor quality of nursing documentation and lack of nurses' knowledge and skills in the nursing process and its application in both paper-based and electronic-based systems. Both forms of documentation revealed drawbacks in terms of content, process and structure. This study provided important information, which can guide policymakers and administrators in identifying effective strategies aimed at enhancing the quality of nursing documentation. Policies and actions to ensure quality nursing documentation at the national level should focus on improving nursing knowledge, competencies, practice in nursing process, enhancing the work environment and nursing workload, as well as strengthening the capacity building of nursing practice to improve the quality of nursing care and

AGREEMENT BETWEEN THE WHITE MATTER CONNECTIVITY BASED ON THE TENSOR-BASED MORPHOMETRY AND THE VOLUMETRIC WHITE MATTER PARCELLATIONS BASED ON DIFFUSION TENSOR IMAGING

OpenAIRE

Kim, Seung-Goo; Lee, Hyekyoung; Chung, Moo K.; Hanson, Jamie L.; Avants, Brian B.; Gee, James C.; Davidson, Richard J.; Pollak, Seth D.

2012-01-01

We are interested in investigating white matter connectivity using a novel computational framework that does not use diffusion tensor imaging (DTI) but only uses T1-weighted magnetic resonance imaging. The proposed method relies on correlating Jacobian determinants across different voxels based on the tensor-based morphometry (TBM) framework. In this paper, we show agreement between the TBM-based white matter connectivity and the DTI-based white matter atlas. As an application, altered white ...

Frame-Based and Subpicture-Based Parallelization Approaches of the HEVC Video Encoder

Directory of Open Access Journals (Sweden)

Héctor Migallón

2018-05-01

Full Text Available The most recent video coding standard, High Efficiency Video Coding (HEVC, is able to significantly improve the compression performance at the expense of a huge computational complexity increase with respect to its predecessor, H.264/AVC. Parallel versions of the HEVC encoder may help to reduce the overall encoding time in order to make it more suitable for practical applications. In this work, we study two parallelization strategies. One of them follows a coarse-grain approach, where parallelization is based on frames, and the other one follows a fine-grain approach, where parallelization is performed at subpicture level. Two different frame-based approaches have been developed. The first one only uses MPI and the second one is a hybrid MPI/OpenMP algorithm. An exhaustive experimental test was carried out to study the performance of both approaches in order to find out the best setup in terms of parallel efficiency and coding performance. Both frame-based and subpicture-based approaches are compared under the same hardware platform. Although subpicture-based schemes provide an excellent performance with high-resolution video sequences, scalability is limited by resolution, and the coding performance worsens by increasing the number of processes. Conversely, the proposed frame-based approaches provide the best results with respect to both parallel performance (increasing scalability and coding performance (not degrading the rate/distortion behavior.

Application of model-based and knowledge-based measuring methods as analytical redundancy

International Nuclear Information System (INIS)

Hampel, R.; Kaestner, W.; Chaker, N.; Vandreier, B.

1997-01-01

The safe operation of nuclear power plants requires the application of modern and intelligent methods of signal processing for the normal operation as well as for the management of accident conditions. Such modern and intelligent methods are model-based and knowledge-based ones being founded on analytical knowledge (mathematical models) as well as experiences (fuzzy information). In addition to the existing hardware redundancies analytical redundancies will be established with the help of these modern methods. These analytical redundancies support the operating staff during the decision-making. The design of a hybrid model-based and knowledge-based measuring method will be demonstrated by the example of a fuzzy-supported observer. Within the fuzzy-supported observer a classical linear observer is connected with a fuzzy-supported adaptation of the model matrices of the observer model. This application is realized for the estimation of the non-measurable variables as steam content and mixture level within pressure vessels with water-steam mixture during accidental depressurizations. For this example the existing non-linearities will be classified and the verification of the model will be explained. The advantages of the hybrid method in comparison to the classical model-based measuring methods will be demonstrated by the results of estimation. The consideration of the parameters which have an important influence on the non-linearities requires the inclusion of high-dimensional structures of fuzzy logic within the model-based measuring methods. Therefore methods will be presented which allow the conversion of these high-dimensional structures to two-dimensional structures of fuzzy logic. As an efficient solution of this problem a method based on cascaded fuzzy controllers will be presented. (author). 2 refs, 12 figs, 5 tabs

Web-based interventions in nursing.

Science.gov (United States)

Im, Eun-Ok; Chang, Sun Ju

2013-02-01

With recent advances in computer and Internet technologies and high funding priority on technological aspects of nursing research, researchers at the field level began to develop, use, and test various types of Web-based interventions. Despite high potential impacts of Web-based interventions, little is still known about Web-based interventions in nursing. In this article, to identify strengths and weaknesses of Web-based nursing interventions, a literature review was conducted using multiple databases with combined keywords of "online," "Internet" or "Web," "intervention," and "nursing." A total of 95 articles were retrieved through the databases and sorted by research topics. These articles were then analyzed to identify strengths and weaknesses of Web-based interventions in nursing. A strength of the Web-based interventions was their coverage of various content areas. In addition, many of them were theory-driven. They had advantages in their flexibility and comfort. They could provide consistency in interventions and require less cost in the intervention implementation. However, Web-based intervention studies had selected participants. They lacked controllability and had high dropouts. They required technical expertise and high development costs. Based on these findings, directions for future Web-based intervention research were provided.

Pilot-based parametric channel estimation algorithm for DCO-OFDM-based visual light communications

Science.gov (United States)

Qian, Xuewen; Deng, Honggui; He, Hailang

2017-10-01

Due to wide modulation bandwidth in optical communication, multipath channels may be non-sparse and deteriorate communication performance heavily. Traditional compressive sensing-based channel estimation algorithm cannot be employed in this kind of situation. In this paper, we propose a practical parametric channel estimation algorithm for orthogonal frequency division multiplexing (OFDM)-based visual light communication (VLC) systems based on modified zero correlation code (ZCC) pair that has the impulse-like correlation property. Simulation results show that the proposed algorithm achieves better performances than existing least squares (LS)-based algorithm in both bit error ratio (BER) and frequency response estimation.

Form-based Approaches vs. Task-Based Approaches

Directory of Open Access Journals (Sweden)

Zahra Talebi

2015-07-01

Full Text Available This study aimed at investigating whether task-based approaches bear any superiority to that of more traditional ones evident in presentation-practice- and production phase .to fulfill the purpose of the study, the participants within the age range of 11-19, took part in the study. Following a pretest, treatment, and a posttest, the obtained data was analyzed using analysis of covariance (ANCOVA to examine the effects of the variables. The results of the analysis showed that participants in the PPP group did significantly better in the grammar recognition of the posttest than that of the task group. However, their counterparts in the task group gained better scores in the writing section of the test .this research study provided evidence in support of task proponents' claim in the merit of task-based activity in raising learners' implicit knowledge claiming to play the primary role in spontaneous speech.

Rule-Based Reasoning Is Fast and Belief-Based Reasoning Can Be Slow: Challenging Current Explanations of Belief-Bias and Base-Rate Neglect

Science.gov (United States)

Newman, Ian R.; Gibb, Maia; Thompson, Valerie A.

2017-01-01

It is commonly assumed that belief-based reasoning is fast and automatic, whereas rule-based reasoning is slower and more effortful. Dual-Process theories of reasoning rely on this speed-asymmetry explanation to account for a number of reasoning phenomena, such as base-rate neglect and belief-bias. The goal of the current study was to test this…

Functional properties of edible agar-based and starch-based films for food quality preservation.

Science.gov (United States)

Phan, The D; Debeaufort, F; Luu, D; Voilley, A

2005-02-23

Edible films made of agar (AG), cassava starch (CAS), normal rice starch (NRS), and waxy (glutinous) rice starch (WRS) were elaborated and tested for a potential use as edible packaging or coating. Their water vapor permeabilities (WVP) were comparable with those of most of the polysaccharide-based films and with some protein-based films. Depending on the environmental moisture pressure, the WVP of the films varies and remains constant when the relative humidity (RH) is >84%. Equilibrium sorption isotherms of these films have been measured; the Guggenheim-Anderson-de Boer (GAB) model was used to describe the sorption isotherm and contributed to a better knowledge of hydration properties. Surface hydrophobicity and wettability of these films were also investigated using the sessile drop contact angle method. The results obtained suggested the migration of the lipid fraction toward evaporation surface during film drying. Among these polysaccharide-based films, AG-based film and CAS-based film displayed more interesting mechanical properties: they are transparent, clear, homogeneous, flexible, and easily handled. NRS- and WRS-based films were relatively brittle and have a low tension resistance. Microstructure of film cross section was observed by environmental scanning electron microscopy to better understand the effect of the structure on the functional properties. The results suggest that AG-based film and CAS-based films, which show better functional properties, are promising systems to be used as food packaging or coating instead of NRS- and WRS-based films.

Soluble adenylyl cyclase is an acid-base sensor in epithelial base-secreting cells.

Science.gov (United States)

Roa, Jinae N; Tresguerres, Martin

2016-08-01

Blood acid-base regulation by specialized epithelia, such as gills and kidney, requires the ability to sense blood acid-base status. Here, we developed primary cultures of ray (Urolophus halleri) gill cells to study mechanisms for acid-base sensing without the interference of whole animal hormonal regulation. Ray gills have abundant base-secreting cells, identified by their noticeable expression of vacuolar-type H(+)-ATPase (VHA), and also express the evolutionarily conserved acid-base sensor soluble adenylyl cyclase (sAC). Exposure of cultured cells to extracellular alkalosis (pH 8.0, 40 mM HCO3 (-)) triggered VHA translocation to the cell membrane, similar to previous reports in live animals experiencing blood alkalosis. VHA translocation was dependent on sAC, as it was blocked by the sAC-specific inhibitor KH7. Ray gill base-secreting cells also express transmembrane adenylyl cyclases (tmACs); however, tmAC inhibition by 2',5'-dideoxyadenosine did not prevent alkalosis-dependent VHA translocation, and tmAC activation by forskolin reduced the abundance of VHA at the cell membrane. This study demonstrates that sAC is a necessary and sufficient sensor of extracellular alkalosis in ray gill base-secreting cells. In addition, this study indicates that different sources of cAMP differentially modulate cell biology. Copyright © 2016 the American Physiological Society.

LOCATION-BASED SERVICES USING SIP

OpenAIRE

Abdullah Azfar,; Md. Sakhawat Hossen,; María José Peroza Marval; Razib Hayat Khan

2010-01-01

Due to the popularity of Location-Based Services and IP telephony, we decided to review a number of different proposals to implement Location-Based Services over a SIP-based mobile network. The result is an interesting overview about the potential functionalities of Location-Based Services and the capabilities of SIP for implementingthese services.

Nanoplatform-based molecular imaging

National Research Council Canada - National Science Library

Chen, Xiaoyuan

2011-01-01

"Nanoplathform-Based Molecular Imaging provides rationale for using nanoparticle-based probes for molecular imaging, then discusses general strategies for this underutilized, yet promising, technology...

Base

DEFF Research Database (Denmark)

Hjulmand, Lise-Lotte; Johansson, Christer

2004-01-01

BASE - Engelsk basisgrammatik er resultatet af Lise-Lotte Hjulmands grundige bearbejdning og omfattende revidering af Christer Johanssons Engelska basgrammatik. Grammatikken adskiller sig fra det svenske forlæg på en lang række punkter. Den er bl.a. tilpasset til et dansk publikum og det danske...

76 FR 42395 - Business Conduct Standards for Security-Based Swap Dealers and Major Security-Based Swap...

Science.gov (United States)

2011-07-18

... Business Conduct Standards for Security-Based Swap Dealers and Major Security-Based Swap Participants...-11] RIN 3235-AL10 Business Conduct Standards for Security-Based Swap Dealers and Major Security-Based...'') relating to external business conduct standards for security-based swap dealers (``SBS Dealers'') and major...

AGREEMENT BETWEEN THE WHITE MATTER CONNECTIVITY BASED ON THE TENSOR-BASED MORPHOMETRY AND THE VOLUMETRIC WHITE MATTER PARCELLATIONS BASED ON DIFFUSION TENSOR IMAGING.

Science.gov (United States)

Kim, Seung-Goo; Lee, Hyekyoung; Chung, Moo K; Hanson, Jamie L; Avants, Brian B; Gee, James C; Davidson, Richard J; Pollak, Seth D

2012-01-01

We are interested in investigating white matter connectivity using a novel computational framework that does not use diffusion tensor imaging (DTI) but only uses T1-weighted magnetic resonance imaging. The proposed method relies on correlating Jacobian determinants across different voxels based on the tensor-based morphometry (TBM) framework. In this paper, we show agreement between the TBM-based white matter connectivity and the DTI-based white matter atlas. As an application, altered white matter connectivity in a clinical population is determined.

Report on Pairing-based Cryptography.

Science.gov (United States)

Moody, Dustin; Peralta, Rene; Perlner, Ray; Regenscheid, Andrew; Roginsky, Allen; Chen, Lily

2015-01-01

This report summarizes study results on pairing-based cryptography. The main purpose of the study is to form NIST's position on standardizing and recommending pairing-based cryptography schemes currently published in research literature and standardized in other standard bodies. The report reviews the mathematical background of pairings. This includes topics such as pairing-friendly elliptic curves and how to compute various pairings. It includes a brief introduction to existing identity-based encryption (IBE) schemes and other cryptographic schemes using pairing technology. The report provides a complete study of the current status of standard activities on pairing-based cryptographic schemes. It explores different application scenarios for pairing-based cryptography schemes. As an important aspect of adopting pairing-based schemes, the report also considers the challenges inherent in validation testing of cryptographic algorithms and modules. Based on the study, the report suggests an approach for including pairing-based cryptography schemes in the NIST cryptographic toolkit. The report also outlines several questions that will require further study if this approach is followed.

Development of a tool for knowledge base verification of expert system based on Design/CPN

International Nuclear Information System (INIS)

Kim, Jong Hyun

1998-02-01

Verification is a necessary work in developing a reliable expert system. Verification is a process aimed at demonstrating whether a system meets it's specified requirements. As expert systems are used in various applications, the knowledge base verification of systems takes an important position. The conventional Petri net approach that has been studied recently in order to verify the knowledge base is found that it is inadequate to verify the knowledge base of large and complex system, such as alarm processing system of nuclear power plant. Thus, we propose an improved method that models the knowledge base as enhanced colored Petri net. In this study, we analyze the reachability and the error characteristics of the knowledge base. Generally, verification process requires computational support by automated tools. For this reason, this study developed a tool for knowledge base verification based on Design/CPN, which is a tool for editing, modeling, and simulating Colored Petri net. This tool uses Enhanced Colored Petri net as a modeling method. By applying this tool to the knowledge base of nuclear power plant, it is noticed that it can successfully check most of the anomalies that can occur in a knowledge base

A Web-Based Rice Plant Expert System Using Rule-Based Reasoning

Directory of Open Access Journals (Sweden)

Anton Setiawan Honggowibowo

2009-12-01

Full Text Available Rice plants can be attacked by various kinds of diseases which are possible to be determined from their symptoms. However, it is to recognize that to find out the exact type of disease, an agricultural expert’s opinion is needed, meanwhile the numbers of agricultural experts are limited and there are too many problems to be solved at the same time. This makes a system with a capability as an expert is required. This system must contain the knowledge of the diseases and symptom of rice plants as an agricultural expert has to have. This research designs a web-based expert system using rule-based reasoning. The rule are modified from the method of forward chaining inference and backward chaining in order to to help farmers in the rice plant disease diagnosis. The web-based rice plants disease diagnosis expert system has the advantages to access and use easily. With web-based features inside, it is expected that the farmer can accesse the expert system everywhere to overcome the problem to diagnose rice diseases.

Optimal, Reliability-Based Code Calibration

DEFF Research Database (Denmark)

Sørensen, John Dalsgaard

2002-01-01

Reliability based code calibration is considered in this paper. It is described how the results of FORM based reliability analysis may be related to the partial safety factors and characteristic values. The code calibration problem is presented in a decision theoretical form and it is discussed how...... of reliability based code calibration of LRFD based design codes....

Isochronous cyclotron data base description

International Nuclear Information System (INIS)

Kiyan, I.N.; Vorozhtsov, S.B.; Tarashkevich, R.

2004-01-01

The relational data base of the control parameters of the isochronous cyclotron, Isochronous Cyclotron Data Base (ICDB), is described. The relational data base under consideration, written in Transact SQL for the MS SQL Server 2000 with the use of MS Enterprise Manager and MS Query Analyzer, was installed on the server of the AIC144 isochronous cyclotron in Krakow, which operates under the control of the operating system MS Windows Server 2003 (Standard Edition). The interface of the data base under considerations is written in C++ with the use of Visual C++ .NET and is built in the Cyclotron Operator Help Program (COHP), which is used for modeling the operational modes of the isochronous cyclotron. Communication between the COHP and the relational data base is realised on the base of the Open Data Base Connectivity protocol. The relational data base of the control parameter of the isochronous cyclotron is intended: firstly, for systematization and automatic use of all measured and modelled magnetic field maps in the process of modeling the operational modes; secondly, for systematization and convenient access to the stored operational modes; thirdly, for simplifying the operator's work. The relational data base of the control parameter of the isochronous cyclotron reflects its physical structure and the logic of its operator's work. (author)

Exploring policy impacts for servicising in product-based markets : A generic agent-based model

NARCIS (Netherlands)

van der Veen, R.A.C.; Kisjes, K.H.; Nikolic, I.

2017-01-01

The shift to markets based on servicising, i.e. market-level transitions from product-based to service-based production and consumption patterns, may contribute to achieve absolute decoupling, i.e. the combined development of economic growth and environmental impact reduction. However, the

Lecture-based versus problem-based learning in ethics education among nursing students.

Science.gov (United States)

Khatiban, Mahnaz; Falahan, Seyede Nayereh; Amini, Roya; Farahanchi, Afshin; Soltanian, Alireza

2018-01-01

Moral reasoning is a vital skill in the nursing profession. Teaching moral reasoning to students is necessary toward promoting nursing ethics. The aim of this study was to compare the effectiveness of problem-based learning and lecture-based methods in ethics education in improving (1) moral decision-making, (2) moral reasoning, (3) moral development, and (4) practical reasoning among nursing students. This is a repeated measurement quasi-experimental study. Participants and research context: The participants were nursing students in a University of Medical Sciences in west of Iran who were randomly assigned to the lecture-based (n = 33) or the problem-based learning (n = 33) groups. The subjects were provided nursing ethics education in four 2-h sessions. The educational content was similar, but the training methods were different. The subjects completed the Nursing Dilemma Test before, immediately after, and 1 month after the training. The data were analyzed and compared using the SPSS-16 software. Ethical considerations: The program was explained to the students, all of whom signed an informed consent form at the baseline. The two groups were similar in personal characteristics (p > 0.05). A significant improvement was observed in the mean scores on moral development in the problem-based learning compared with the lecture-based group (p ethics education enhances moral development among nursing students. However, further studies are needed to determine whether such method improves moral decision-making, moral reasoning, practical considerations, and familiarity with the ethical issues among nursing students.

Game-Based Teaching

DEFF Research Database (Denmark)

Hanghøj, Thorkild

2013-01-01

This chapter outlines theoretical and empirical perspectives on how Game-Based Teaching can be integrated within the context of formal schooling. Initially, this is done by describing game scenarios as models for possible actions that need to be translated into curricular knowledge practices...... approaches to game-based teaching, which may or may not correspond with the pedagogical models of particular games....

Reliability-Based Code Calibration

DEFF Research Database (Denmark)

Faber, M.H.; Sørensen, John Dalsgaard

2003-01-01

The present paper addresses fundamental concepts of reliability based code calibration. First basic principles of structural reliability theory are introduced and it is shown how the results of FORM based reliability analysis may be related to partial safety factors and characteristic values....... Thereafter the code calibration problem is presented in its principal decision theoretical form and it is discussed how acceptable levels of failure probability (or target reliabilities) may be established. Furthermore suggested values for acceptable annual failure probabilities are given for ultimate...... and serviceability limit states. Finally the paper describes the Joint Committee on Structural Safety (JCSS) recommended procedure - CodeCal - for the practical implementation of reliability based code calibration of LRFD based design codes....

Preparing for budget-based payment methodologies: global payment and episode-based payment.

Science.gov (United States)

Hudson, Mark E

2015-10-01

Use of budget-based payment methodologies (capitation and episode-based bundled payment) has been demonstrated to drive value in healthcare delivery. With a focus on high-volume, high-cost surgical procedures, inclusion of anaesthesiology services in these methodologies is likely. This review provides a summary of budget-based payment methodologies and practical information necessary for anaesthesiologists to prepare for participation in these programmes. Although few examples of anaesthesiologists' participation in these models exist, an understanding of the structure of these programmes and opportunities for participation are available. Prospective preparation in developing anaesthesiology-specific bundled payment profiles and early participation in pathway development associated with selected episodes of care are essential for successful participation as a gainsharing partner. With significant opportunity to contribute to care coordination and cost management, anaesthesiology can play an important role in budget-based payment programmes and should expect to participate as full gainsharing partners. Precise costing methodologies and accurate economic modelling, along with identification of quality management and cost control opportunities, will help identify participation opportunities and appropriate payment and gainsharing agreements. Anaesthesiology-specific examples with budget-based payment models are needed to help guide increased participation in these programmes.

Current-based detection of nonlocal spin transport in graphene for spin-based logic applications

Science.gov (United States)

Wen, Hua; Zhu, Tiancong; Luo, Yunqiu Kelly; Amamou, Walid; Kawakami, Roland K.

2014-05-01

Graphene has been proposed for novel spintronic devices due to its robust and efficient spin transport properties at room temperature. Some of the most promising proposals require current-based readout for integration purposes, but the current-based detection of spin accumulation has not yet been developed. In this work, we demonstrate current-based detection of spin transport in graphene using a modified nonlocal geometry. By adding a variable shunt resistor in parallel to the nonlocal voltmeter, we are able to systematically cross over from the conventional voltage-based detection to current-based detection. As the shunt resistor is reduced, the output current from the spin accumulation increases as the shunt resistance drops below a characteristic value R*. We analyze this behavior using a one-dimensional drift-diffusion model, which accounts well for the observed behavior. These results provide the experimental and theoretical foundation for current-based detection of nonlocal spin transport.

Greater fruit selection following an appearance-based compared with a health-based health promotion poster

Science.gov (United States)

2016-01-01

Abstract Background This study investigated the impact of an appearance-based compared with a traditional health-based public health message for healthy eating. Methods A total of 166 British University students (41 males; aged 20.6 ± 1.9 years) were randomized to view either an appearance-based (n = 82) or a health-based (n = 84) fruit promotion poster. Intentions to consume fruit and immediate fruit selection (laboratory observation) were assessed immediately after poster viewing, and subsequent self-report fruit consumption was assessed 3 days later. Results Intentions to consume fruit were not predicted by poster type (largest β = 0.03, P = 0.68) but were associated with fruit-based liking, past consumption, attitudes and social norms (smallest β = 0.16, P = 0.04). Immediate fruit selection was greater following the appearance-based compared with the health-based poster (β = −0.24, P poster (β = −0.22, P = 0.03), but this effect became non-significant on consideration of participant characteristics (β = −0.15, P = 0.13), and was instead associated with fruit-based liking and past consumption (smallest β = 0.24, P = 0.03). Conclusions These findings demonstrate the clear value of an appearance-based compared with a health-based health promotion poster for increasing fruit selection. A distinction between outcome measures and the value of a behavioural measure is also demonstrated. PMID:28158693

Portraits of Middle School Students Constructing Evidence-Based Arguments during Problem-Based Learning: The Impact of Computer-Based Scaffolds

Science.gov (United States)

Belland, Brian R.

2010-01-01

A critical step in problem-based learning (PBL) units occurs when groups present their solution to the central problem. This is challenging for middle school students because it involves the creation of an evidence-based argument (Krajcik et al., "Journal of the Learning Sciences" 7:313-350, 1998). Using a mixed method design, this study…

Rule-Based vs. Behavior-Based Self-Deployment for Mobile Wireless Sensor Networks.

Science.gov (United States)

Urdiales, Cristina; Aguilera, Francisco; González-Parada, Eva; Cano-García, Jose; Sandoval, Francisco

2016-07-07

In mobile wireless sensor networks (MWSN), nodes are allowed to move autonomously for deployment. This process is meant: (i) to achieve good coverage; and (ii) to distribute the communication load as homogeneously as possible. Rather than optimizing deployment, reactive algorithms are based on a set of rules or behaviors, so nodes can determine when to move. This paper presents an experimental evaluation of both reactive deployment approaches: rule-based and behavior-based ones. Specifically, we compare a backbone dispersion algorithm with a social potential fields algorithm. Most tests are done under simulation for a large number of nodes in environments with and without obstacles. Results are validated using a small robot network in the real world. Our results show that behavior-based deployment tends to provide better coverage and communication balance, especially for a large number of nodes in areas with obstacles.

Influence of yielding base and rigid base on propagation of Rayleigh ...

Indian Academy of Sciences (India)

The present study aims to study the propagation of Rayleigh-type wave in a layer, composed of isotropic viscoelastic material of Voigt type, with the effect of yielding base and rigid base in two distinct cases.With the aid of an analytical treatment, closed-form expressions of phase velocity and damped velocity for both the ...

Recognition of chemical entities: combining dictionary-based and grammar-based approaches

Science.gov (United States)

2015-01-01

Background The past decade has seen an upsurge in the number of publications in chemistry. The ever-swelling volume of available documents makes it increasingly hard to extract relevant new information from such unstructured texts. The BioCreative CHEMDNER challenge invites the development of systems for the automatic recognition of chemicals in text (CEM task) and for ranking the recognized compounds at the document level (CDI task). We investigated an ensemble approach where dictionary-based named entity recognition is used along with grammar-based recognizers to extract compounds from text. We assessed the performance of ten different commercial and publicly available lexical resources using an open source indexing system (Peregrine), in combination with three different chemical compound recognizers and a set of regular expressions to recognize chemical database identifiers. The effect of different stop-word lists, case-sensitivity matching, and use of chunking information was also investigated. We focused on lexical resources that provide chemical structure information. To rank the different compounds found in a text, we used a term confidence score based on the normalized ratio of the term frequencies in chemical and non-chemical journals. Results The use of stop-word lists greatly improved the performance of the dictionary-based recognition, but there was no additional benefit from using chunking information. A combination of ChEBI and HMDB as lexical resources, the LeadMine tool for grammar-based recognition, and the regular expressions, outperformed any of the individual systems. On the test set, the F-scores were 77.8% (recall 71.2%, precision 85.8%) for the CEM task and 77.6% (recall 71.7%, precision 84.6%) for the CDI task. Missed terms were mainly due to tokenization issues, poor recognition of formulas, and term conjunctions. Conclusions We developed an ensemble system that combines dictionary-based and grammar-based approaches for chemical named

Recognition of chemical entities: combining dictionary-based and grammar-based approaches.

Science.gov (United States)

Akhondi, Saber A; Hettne, Kristina M; van der Horst, Eelke; van Mulligen, Erik M; Kors, Jan A

2015-01-01

The past decade has seen an upsurge in the number of publications in chemistry. The ever-swelling volume of available documents makes it increasingly hard to extract relevant new information from such unstructured texts. The BioCreative CHEMDNER challenge invites the development of systems for the automatic recognition of chemicals in text (CEM task) and for ranking the recognized compounds at the document level (CDI task). We investigated an ensemble approach where dictionary-based named entity recognition is used along with grammar-based recognizers to extract compounds from text. We assessed the performance of ten different commercial and publicly available lexical resources using an open source indexing system (Peregrine), in combination with three different chemical compound recognizers and a set of regular expressions to recognize chemical database identifiers. The effect of different stop-word lists, case-sensitivity matching, and use of chunking information was also investigated. We focused on lexical resources that provide chemical structure information. To rank the different compounds found in a text, we used a term confidence score based on the normalized ratio of the term frequencies in chemical and non-chemical journals. The use of stop-word lists greatly improved the performance of the dictionary-based recognition, but there was no additional benefit from using chunking information. A combination of ChEBI and HMDB as lexical resources, the LeadMine tool for grammar-based recognition, and the regular expressions, outperformed any of the individual systems. On the test set, the F-scores were 77.8% (recall 71.2%, precision 85.8%) for the CEM task and 77.6% (recall 71.7%, precision 84.6%) for the CDI task. Missed terms were mainly due to tokenization issues, poor recognition of formulas, and term conjunctions. We developed an ensemble system that combines dictionary-based and grammar-based approaches for chemical named entity recognition, outperforming

Barrier Data Base user's guide

International Nuclear Information System (INIS)

Worrell, R.B.; Gould, D.J.; Wall, D.W.

1977-06-01

A special purpose data base for physical security barriers has been developed. In addition to barriers, the entities accommodated by the Barrier Data Base (BDB) include threats and references. A threat is established as a configuration of people and equipment which has been employed to penetrate (or attempt to penetrate) a barrier. References are used to cite publications pertinent to the barriers and threats in the data base. Utilization and maintenance of the Barrier Data Base is achieved with LIST, QUERY, ENTER, DELETE, and CHANGE commands which are used to manipulate the data base entities

Hyperspectral Data for Mangrove Species Mapping: A Comparison of Pixel-Based and Object-Based Approach

Directory of Open Access Journals (Sweden)

Muhammad Kamal

2011-10-01

Full Text Available Visual image interpretation and digital image classification have been used to map and monitor mangrove extent and composition for decades. The presence of a high-spatial resolution hyperspectral sensor can potentially improve our ability to differentiate mangrove species. However, little research has explored the use of pixel-based and object-based approaches on high-spatial hyperspectral datasets for this purpose. This study assessed the ability of CASI-2 data for mangrove species mapping using pixel-based and object-based approaches at the mouth of the Brisbane River area, southeast Queensland, Australia. Three mapping techniques used in this study: spectral angle mapper (SAM and linear spectral unmixing (LSU for the pixel-based approaches, and multi-scale segmentation for the object-based image analysis (OBIA. The endmembers for the pixel-based approach were collected based on existing vegetation community map. Nine targeted classes were mapped in the study area from each approach, including three mangrove species: Avicennia marina, Rhizophora stylosa, and Ceriops australis. The mapping results showed that SAM produced accurate class polygons with only few unclassified pixels (overall accuracy 69%, Kappa 0.57, the LSU resulted in a patchy polygon pattern with many unclassified pixels (overall accuracy 56%, Kappa 0.41, and the object-based mapping produced the most accurate results (overall accuracy 76%, Kappa 0.67. Our results demonstrated that the object-based approach, which combined a rule-based and nearest-neighbor classification method, was the best classifier to map mangrove species and its adjacent environments.

Carbon-Based Nanomaterials in Biomass-Based Fuel-Fed Fuel Cells

Directory of Open Access Journals (Sweden)

Le Quynh Hoa

2017-11-01

Full Text Available Environmental and sustainable economical concerns are generating a growing interest in biofuels predominantly produced from biomass. It would be ideal if an energy conversion device could directly extract energy from a sustainable energy resource such as biomass. Unfortunately, up to now, such a direct conversion device produces insufficient power to meet the demand of practical applications. To realize the future of biofuel-fed fuel cells as a green energy conversion device, efforts have been devoted to the development of carbon-based nanomaterials with tunable electronic and surface characteristics to act as efficient metal-free electrocatalysts and/or as supporting matrix for metal-based electrocatalysts. We present here a mini review on the recent advances in carbon-based catalysts for each type of biofuel-fed/biofuel cells that directly/indirectly extract energy from biomass resources, and discuss the challenges and perspectives in this developing field.

Knowledge-based machine indexing from natural language text: Knowledge base design, development, and maintenance

Science.gov (United States)

Genuardi, Michael T.

1993-01-01

One strategy for machine-aided indexing (MAI) is to provide a concept-level analysis of the textual elements of documents or document abstracts. In such systems, natural-language phrases are analyzed in order to identify and classify concepts related to a particular subject domain. The overall performance of these MAI systems is largely dependent on the quality and comprehensiveness of their knowledge bases. These knowledge bases function to (1) define the relations between a controlled indexing vocabulary and natural language expressions; (2) provide a simple mechanism for disambiguation and the determination of relevancy; and (3) allow the extension of concept-hierarchical structure to all elements of the knowledge file. After a brief description of the NASA Machine-Aided Indexing system, concerns related to the development and maintenance of MAI knowledge bases are discussed. Particular emphasis is given to statistically-based text analysis tools designed to aid the knowledge base developer. One such tool, the Knowledge Base Building (KBB) program, presents the domain expert with a well-filtered list of synonyms and conceptually-related phrases for each thesaurus concept. Another tool, the Knowledge Base Maintenance (KBM) program, functions to identify areas of the knowledge base affected by changes in the conceptual domain (for example, the addition of a new thesaurus term). An alternate use of the KBM as an aid in thesaurus construction is also discussed.

Semi-active control of magnetorheological elastomer base isolation system utilising learning-based inverse model

Science.gov (United States)

Gu, Xiaoyu; Yu, Yang; Li, Jianchun; Li, Yancheng

2017-10-01

Magnetorheological elastomer (MRE) base isolations have attracted considerable attention over the last two decades thanks to its self-adaptability and high-authority controllability in semi-active control realm. Due to the inherent nonlinearity and hysteresis of the devices, it is challenging to obtain a reasonably complicated mathematical model to describe the inverse dynamics of MRE base isolators and hence to realise control synthesis of the MRE base isolation system. Two aims have been achieved in this paper: i) development of an inverse model for MRE base isolator based on optimal general regression neural network (GRNN); ii) numerical and experimental validation of a real-time semi-active controlled MRE base isolation system utilising LQR controller and GRNN inverse model. The superiority of GRNN inverse model lays in fewer input variables requirement, faster training process and prompt calculation response, which makes it suitable for online training and real-time control. The control system is integrated with a three-storey shear building model and control performance of the MRE base isolation system is compared with bare building, passive-on isolation system and passive-off isolation system. Testing results show that the proposed GRNN inverse model is able to reproduce desired control force accurately and the MRE base isolation system can effectively suppress the structural responses when compared to the passive isolation system.

Additivity of Feature-based and Symmetry-based Grouping Effects in Multiple Object Tracking

Directory of Open Access Journals (Sweden)

Chundi eWang

2016-05-01

Full Text Available Multiple object tracking (MOT is an attentional process wherein people track several moving targets among several distractors. Symmetry, an important indicator of regularity, is a general spatial pattern observed in natural and artificial scenes. According to the laws of perceptual organization proposed by Gestalt psychologists, regularity is a principle of perceptual grouping, such as similarity and closure. A great deal of research reported that feature-based similarity grouping (e.g., grouping based on color, size, or shape among targets in MOT tasks can improve tracking performance. However, no additive feature-based grouping effects have been reported where the tracking objects had two or more features. Additive effect refers to a greater grouping effect produced by grouping based on multiple cues instead of one cue. Can spatial symmetry produce a similar grouping effect similar to that of feature similarity in MOT tasks? Are the grouping effects based on symmetry and feature similarity additive? This study includes four experiments to address these questions. The results of Experiments 1 and 2 demonstrated the automatic symmetry-based grouping effects. More importantly, an additive grouping effect of symmetry and feature similarity was observed in Experiments 3 and 4. Our findings indicate that symmetry can produce an enhanced grouping effect in MOT and facilitate the grouping effect based on color or shape similarity. The where and what pathways might have played an important role in the additive grouping effect.

New approach for risk based inspection of H2S based Process Plants

International Nuclear Information System (INIS)

Vinod, Gopika; Sharma, Pavan K.; Santosh, T.V.; Hari Prasad, M.; Vaze, K.K.

2014-01-01

Highlights: • Study looks into improving the consequence evaluation in risk based inspection. • Ways to revise the quantity factors used in qualitative approach. • New approach based on computational fluid dynamics along with probit mathematics. • Demonstrated this methodology along with a suitable case study for the said issue. - Abstract: Recent trend in risk informed and risk based approaches in life management issues have certainly put the focus on developing estimation methods for real risk. Idea of employing risk as an optimising measure for in-service inspection, termed as risk based inspection, was accepted in principle from late 80s. While applying risk based inspection, consequence of failure from each component needs to be assessed. Consequence evaluation in a Process Plant is a crucial task. It may be noted that, in general, the number of components to be considered for life management is very large and hence the consequence evaluation resulting from their failures (individually) is a laborious task. Screening of critical components is usually carried out using simplified qualitative approach, which primarily uses influence factors for categorisation. This necessitates logical formulation of influence factors and their ranges with a suitable technical basis for acceptance from regulators. This paper describes application of risk based inspection for H 2 S based Process Plant along with the approach devised for handling the influence factor related to the quantity of H 2 S released

Performance Based Failure Criteria of the Base Isolation System for Nuclear Power Plants

International Nuclear Information System (INIS)

Kim, Jung Han; Kim, Min Kyu; Choi, In Kil

2013-01-01

The realistic approach to evaluate the failure state of the base isolation system is necessary. From this point of view, several concerns are reviewed and discussed in this study. This is the preliminary study for the performance based risk assessment of a base isolated nuclear power plant. The items to evaluate the capacity and response of an individual base isolator and a base isolation system were briefly outlined. However, the methodology to evaluate the realistic fragility of a base isolation system still needs to be specified. For the quantification of the seismic risk for a nuclear power plant structure, the failure probabilities of the structural component for the various seismic intensity levels need to be calculated. The failure probability is evaluated as the probability when the seismic response of a structure exceeds the failure criteria. Accordingly, the failure mode of the structural system caused by an earthquake vibration should be defined first. The type of a base isolator appropriate for a nuclear power plant structure is regarded as an elastometric rubber bearing with a lead core. The failure limit of the lead-rubber bearing (LRB) is not easy to be predicted because of its high nonlinearity and a complex loading condition by an earthquake excitation. Furthermore, the failure mode of the LRB system installed below the nuclear island cannot be simply determined because the basemat can be sufficiently supported if the number of damaged isolator is not much

Evaluation of medical students of teacher-based and student-based teaching methods in Infectious diseases course.

Science.gov (United States)

Ghasemzadeh, I; Aghamolaei, T; Hosseini-Parandar, F

2015-01-01

Introduction: In recent years, medical education has changed dramatically and many medical schools in the world have been trying for expand modern training methods. Purpose of the research is to appraise the medical students of teacher-based and student-based teaching methods in Infectious diseases course, in the Medical School of Hormozgan Medical Sciences University. Methods: In this interventional study, a total of 52 medical scholars that used Section in this Infectious diseases course were included. About 50% of this course was presented by a teacher-based teaching method (lecture) and 50% by a student-based teaching method (problem-based learning). The satisfaction of students regarding these methods was assessed by a questionnaire and a test was used to measure their learning. information are examined with using SPSS 19 and paired t-test. Results: The satisfaction of students of student-based teaching method (problem-based learning) was more positive than their satisfaction of teacher-based teaching method (lecture).The mean score of students in teacher-based teaching method was 12.03 (SD=4.08) and in the student-based teaching method it was 15.50 (SD=4.26) and where is a considerable variation among them (p<0.001). Conclusion: The use of the student-based teaching method (problem-based learning) in comparison with the teacher-based teaching method (lecture) to present the Infectious diseases course led to the student satisfaction and provided additional learning opportunities.

Accurate interaction energies of base pairing and base stacking. The final chapter

Czech Academy of Sciences Publication Activity Database

Šponer, Jiří; Jurečka, Petr; Hobza, Pavel

2005-01-01

Roč. 22, č. 6 (2005), s. 767 ISSN 0739-1102. [Albany 2005. Conversation /14./. 14.06.2005-18.06.2005, Albany] Institutional research plan: CEZ:AV0Z50040507 Keywords : base pairing * base stacking * nucleic acids Subject RIV: BO - Biophysics

Base Station Performance Model

OpenAIRE

Walsh, Barbara; Farrell, Ronan

2005-01-01

At present the testing of power amplifiers within base station transmitters is limited to testing at component level as opposed to testing at the system level. While the detection of catastrophic failure is possible, that of performance degradation is not. This paper proposes a base station model with respect to transmitter output power with the aim of introducing system level monitoring of the power amplifier behaviour within the base station. Our model reflects the expe...

DOE's energy data base (EDB) versus other energy-related data bases: a comparative analysis

International Nuclear Information System (INIS)

Robinson, J.; Hu, M.

1981-02-01

The release of the DOE Energy Data Base to commercial services in 1980 raised an immediate question in the minds of some searchers: how does this new data base fit into the spectrum of already-available data bases. Because the authors have been closely associated with the Department of Energy's RECON system and its data bases for several years, as trainers and as editor of the DOE/RECON Newsletter, the question was of great interest and we decided to investigate it

Nonbinary Tree-Based Phylogenetic Networks.

Science.gov (United States)

Jetten, Laura; van Iersel, Leo

2018-01-01

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic base-tree with additional linking arcs, which can, for example, represent gene transfer events. Such phylogenetic networks are called tree-based. Here, we consider two possible generalizations of this concept to nonbinary networks, which we call tree-based and strictly-tree-based nonbinary phylogenetic networks. We give simple graph-theoretic characterizations of tree-based and strictly-tree-based nonbinary phylogenetic networks. Moreover, we show for each of these two classes that it can be decided in polynomial time whether a given network is contained in the class. Our approach also provides a new view on tree-based binary phylogenetic networks. Finally, we discuss two examples of nonbinary phylogenetic networks in biology and show how our results can be applied to them.

An Intelligent Fleet Condition-Based Maintenance Decision Making Method Based on Multi-Agent

Directory of Open Access Journals (Sweden)

Bo Sun

2012-01-01

Full Text Available According to the demand for condition-based maintenance online decision making among a mission oriented fleet, an intelligent maintenance decision making method based on Multi-agent and heuristic rules is proposed. The process of condition-based maintenance within an aircraft fleet (each containing one or more Line Replaceable Modules based on multiple maintenance thresholds is analyzed. Then the process is abstracted into a Multi-Agent Model, a 2-layer model structure containing host negotiation and independent negotiation is established, and the heuristic rules applied to global and local maintenance decision making is proposed. Based on Contract Net Protocol and the heuristic rules, the maintenance decision making algorithm is put forward. Finally, a fleet consisting of 10 aircrafts on a 3-wave continuous mission is illustrated to verify this method. Simulation results indicate that this method can improve the availability of the fleet, meet mission demands, rationalize the utilization of support resources and provide support for online maintenance decision making among a mission oriented fleet.

Development and characterization of rosin-based polymer and its application as a cream base.

Science.gov (United States)

Dhanorkar, V T; Gawande, R S; Gogte, B B; Dorle, A K

2002-01-01

The literature contains many references to the wide range of uses of rosin-based polymers, but little has appeared in the area of rosin-based polymers used as cream bases. Various rosin polymers based on glycerol, sorbitol, and pentaerythritol were prepared and screened for efficacy as cream bases. Among these polymers, polymer 2 (glycerol-based) is reported in the present study as it produced creams with a better stability and release profile as compared to other creams. The creams were formulated employing polymer 2 (P2) and Tween 60 as surfactants. The stability of the prepared creams, as well as the diclofenac diethylammonium release pattern, was investigated using particle size analysis, conductivity, relative dielectric constant, spreadability, and irritation potential measurement, and was compared with that of creams containing Tween 60 (RT) prepared in the laboratory. The release of the drug, diclofenac diethylammonium, was measured after eight hours and compared with a standard cream (RT) and a marketed cream (RM).

Lattice-Based Revocable Certificateless Signature

Directory of Open Access Journals (Sweden)

Ying-Hao Hung

2017-10-01

Full Text Available Certificateless signatures (CLS are noticeable because they may resolve the key escrow problem in ID-based signatures and break away the management problem regarding certificate in conventional signatures. However, the security of the mostly previous CLS schemes relies on the difficulty of solving discrete logarithm or large integer factorization problems. These two problems would be solved by quantum computers in the future so that the signature schemes based on them will also become insecure. For post-quantum cryptography, lattice-based cryptography is significant due to its efficiency and security. However, no study on addressing the revocation problem in the existing lattice-based CLS schemes is presented. In this paper, we focus on the revocation issue and present the first revocable CLS (RCLS scheme over lattices. Based on the short integer solution (SIS assumption over lattices, the proposed lattice-based RCLS scheme is shown to be existential unforgeability against adaptive chosen message attacks. By performance analysis and comparisons, the proposed lattice-based RCLS scheme is better than the previously proposed lattice-based CLS scheme, in terms of private key size, signature length and the revocation mechanism.

Base Carbone. Documentation about the emission factors of the Base CarboneR database

International Nuclear Information System (INIS)

2014-01-01

The Base Carbone R is a public database of emission factors as required for carrying out carbon accounting exercises. It is administered by ADEME, but its governance involves many stakeholders and it can be added to freely. The articulation and convergence of environmental regulations requires data homogenization. The Base Carbone R proposes to be this centralized data source. Today, it is the reference database for article 75 of the Grenelle II Act. It is also entirely consistent with article L1341-3 of the French Transport Code and the default values of the European emission quotas exchange system. The data of the Base Carbone R can be freely consulted by all. Furthermore, the originality of this tool is that it enables third parties to propose their own data (feature scheduled for February 2015). These data are then assessed for their quality and transparency, then validated or refused for incorporation in the Base Carbone R . Lastly, a forum (planned for February 2015) will enable users to ask questions about the data, or to contest the data. The administration of the Base Carbone R is handled by ADEME. However, its orientation and the data that it contains are validated by a governance committee incorporating various public and private stakeholders. Lastly, transparency is one of the keystones of the Base Carbone R . Documentation details the hypotheses underlying the construction of all the data in the base, and refers to the studies that have enabled their construction. This document brings together the different versions of the Base Carbone R documentation: the most recent version (v11.5) and the previous versions (v11.0) which is shared in 2 parts dealing with the general case and with the specific case of overseas territories

Biocompatibility study on Ni-free Ti-based and Zr-based bulk metallic glasses

Energy Technology Data Exchange (ETDEWEB)

Li, T.H. [Institute of Material Science and Engineering, National Central University, Taoyuan, Taiwan (China); Wong, P.C. [Department of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan (China); Chang, S.F. [Department of Mechanical Engineering, National Central University, Taoyuan, Taiwan (China); Tsai, P.H. [Institute of Material Science and Engineering, National Central University, Taoyuan, Taiwan (China); Jang, J.S.C., E-mail: jscjang@ncu.edu.tw [Institute of Material Science and Engineering, National Central University, Taoyuan, Taiwan (China); Department of Mechanical Engineering, National Central University, Taoyuan, Taiwan (China); Huang, J.C. [Department of Materials and Optoelectronic Science, National Sun Yat-Sen University, Kaohsiung, Taiwan (China)

2017-06-01

Safety and reliability are crucial issues for medical instruments and implants. In the past few decays, bulk metallic glasses (BMGs) have drawn attentions due to their superior mechanical properties, good corrosion resistance, antibacterial and good biocompatibility. However, most Zr-based and Ti-based BMGs contain Ni as an important element which is prone to human allergy problem. In this study, the Ni-free Ti-based and Zr-based BMGs, Ti{sub 40}Zr{sub 10}Cu{sub 36}Pd{sub 14}, and Zr{sub 48}Cu{sub 36}Al{sub 8}Ag{sub 8}, were selected for systematical evaluation of their biocompatibility. Several biocompatibility tests, co-cultural with L929 murine fibroblast cell line, were carried out on these two BMGs, as well as the comparison samples of Ti6Al4V and pure Cu. The results in terms of cellular adhesion, cytotoxicity, and metallic ion release affection reveal that the Ti{sub 40}Zr{sub 10}Cu{sub 36}Pd{sub 14} BMG and Ti6Al4V exhibit the optimum biocompatibility; cells still being attached on the petri dish with good adhesion and exhibiting the spindle shape after direct contact test. Furthermore, the Ti{sub 40}Zr{sub 10}Cu{sub 36}Pd{sub 14} BMG showed very low Cu ion release level, in agreement with the MTT results. Based on the current findings, it is believed that Ni-free Ti-based BMG can act as an ideal candidate for medical implant. - Highlight: • Ni-free bulk metallic glass is promising material for medical implants. • Ni-free Ti-based BMG presents similar cellular adhesion as Ti6Al4V. • Ni-free Ti-based BMG shows less cytotoxicity, and metallic ion release than Ti6Al4V.

SPIRE Data-Base Management System

Science.gov (United States)

Fuechsel, C. F.

1984-01-01

Spacelab Payload Integration and Rocket Experiment (SPIRE) data-base management system (DBMS) based on relational model of data bases. Data bases typically used for engineering and mission analysis tasks and, unlike most commercially available systems, allow data items and data structures stored in forms suitable for direct analytical computation. SPIRE DBMS designed to support data requests from interactive users as well as applications programs.

Eye-based head gestures

DEFF Research Database (Denmark)

Mardanbegi, Diako; Witzner Hansen, Dan; Pederson, Thomas

2012-01-01

A novel method for video-based head gesture recognition using eye information by an eye tracker has been proposed. The method uses a combination of gaze and eye movement to infer head gestures. Compared to other gesture-based methods a major advantage of the method is that the user keeps the gaze...... mobile phone screens. The user study shows that the method detects a set of defined gestures reliably.......A novel method for video-based head gesture recognition using eye information by an eye tracker has been proposed. The method uses a combination of gaze and eye movement to infer head gestures. Compared to other gesture-based methods a major advantage of the method is that the user keeps the gaze...

PROCESS-BASED LEARNING: TOWARDS THEORETICAL AND LECTURE-BASED COURSEWORK IN STUDIO STYLE

Directory of Open Access Journals (Sweden)

Hatem Ezzat Nabih

2010-07-01

Full Text Available This article presents a process-based learning approach to design education where theoretical coursework is taught in studio-style. Lecture-based coursework is sometimes regarded as lacking in challenge and broadening the gap between theory and practice. Furthermore, lecture-based curricula tend to be detached from the studio and deny students from applying their theoretically gained knowledge. Following the belief that student motivation is increased by establishing a higher level of autonomy in the learning process, I argue for a design education that links theory with applied design work within the studio setting. By synthesizing principles of Constructivist Learning and Problem-Based Learning, PBL students are given greater autonomy by being actively involved in their education. Accordingly, I argue for a studio setting that incorporates learning in studio style by presenting three design applications involving students in investigation and experimentation in order to self-experience the design process.

Bus Based Synchronization Method for CHIPPER Based NoC

Directory of Open Access Journals (Sweden)

D. Muralidharan

2016-01-01

Full Text Available Network on Chip (NoC reduces the communication delay of System on Chip (SoC. The main limitation of NoC is power consumption and area overhead. Bufferless NoC reduces the area complexity and power consumption by eliminating buffers in the traditional routers. The bufferless NoC design should include live lock freeness since they use hot potato routing. This increases the complexity of bufferless NoC design. Among the available propositions to reduce this complexity, CHIPPER based bufferless NoC is considered as one of the best options. Live lock freeness is provided in CHIPPER through golden epoch and golden packet. All routers follow some synchronization method to identify a golden packet. Clock based method is intuitively followed for synchronization in CHIPPER based NoCs. It is shown in this work that the worst-case latency of packets is unbearably high when the above synchronization is followed. To alleviate this problem, broadcast bus NoC (BBus NoC approach is proposed in this work. The proposed method decreases the worst-case latency of packets by increasing the golden epoch rate of CHIPPER.

A Lattice-Based Identity-Based Proxy Blind Signature Scheme in the Standard Model

Directory of Open Access Journals (Sweden)

Lili Zhang

2014-01-01

Full Text Available A proxy blind signature scheme is a special form of blind signature which allowed a designated person called proxy signer to sign on behalf of original signers without knowing the content of the message. It combines the advantages of proxy signature and blind signature. Up to date, most proxy blind signature schemes rely on hard number theory problems, discrete logarithm, and bilinear pairings. Unfortunately, the above underlying number theory problems will be solvable in the postquantum era. Lattice-based cryptography is enjoying great interest these days, due to implementation simplicity and provable security reductions. Moreover, lattice-based cryptography is believed to be hard even for quantum computers. In this paper, we present a new identity-based proxy blind signature scheme from lattices without random oracles. The new scheme is proven to be strongly unforgeable under the standard hardness assumption of the short integer solution problem (SIS and the inhomogeneous small integer solution problem (ISIS. Furthermore, the secret key size and the signature length of our scheme are invariant and much shorter than those of the previous lattice-based proxy blind signature schemes. To the best of our knowledge, our construction is the first short lattice-based identity-based proxy blind signature scheme in the standard model.

Case-Based FCTF Reasoning System

Directory of Open Access Journals (Sweden)

Jing Lu

2015-10-01

Full Text Available Case-based reasoning uses old information to infer the answer of new problems. In case-based reasoning, a reasoner firstly records the previous cases, then searches the previous case list that is similar to the current one and uses that to solve the new case. Case-based reasoning means adapting old solving solutions to new situations. This paper proposes a reasoning system based on the case-based reasoning method. To begin, we show the theoretical structure and algorithm of from coarse to fine (FCTF reasoning system, and then demonstrate that it is possible to successfully learn and reason new information. Finally, we use our system to predict practical weather conditions based on previous ones and experiments show that the prediction accuracy increases with further learning of the FCTF reasoning system.

Automated knowledge-base refinement

Science.gov (United States)

Mooney, Raymond J.

1994-01-01

Over the last several years, we have developed several systems for automatically refining incomplete and incorrect knowledge bases. These systems are given an imperfect rule base and a set of training examples and minimally modify the knowledge base to make it consistent with the examples. One of our most recent systems, FORTE, revises first-order Horn-clause knowledge bases. This system can be viewed as automatically debugging Prolog programs based on examples of correct and incorrect I/O pairs. In fact, we have already used the system to debug simple Prolog programs written by students in a programming language course. FORTE has also been used to automatically induce and revise qualitative models of several continuous dynamic devices from qualitative behavior traces. For example, it has been used to induce and revise a qualitative model of a portion of the Reaction Control System (RCS) of the NASA Space Shuttle. By fitting a correct model of this portion of the RCS to simulated qualitative data from a faulty system, FORTE was also able to correctly diagnose simple faults in this system.

Orthogonally Based Digital Content Management Applicable to Projects-bases

Directory of Open Access Journals (Sweden)

Daniel MILODIN

2009-01-01

Full Text Available There is defined the concept of digital content. The requirements of an efficient management of the digital content are established. There are listed the quality characteristics of digital content. Orthogonality indicators of digital content are built up. They are meant to measure the image, the sound as well as the text orthogonality as well. Projects-base concept is introduced. There is presented the model of structuring the content in order to maximize orthogonality via a convergent iterative process. The model is instantiated for the digital content of a projects-base. It is introduced the application used to test the model. The paper ends with conclusions.

Thermal insulation coating based on water-based polymer dispersion

Directory of Open Access Journals (Sweden)

Panchenko Iuliia

2018-01-01

Full Text Available For Russia, due to its long winter period, improvement of thermal insulation properties of envelope structures by applying thermal insulation paint and varnish coating to its inner surface is considered perspective. Thermal insulation properties of such coatings are provided by adding aluminosilicate microspheres and aluminum pigment to their composition. This study was focused on defining the effect of hollow aluminosilicate microspheres and aluminum pigment on the paint thermal insulation coating based on water-based polymer dispersion and on its optimum filling ratio. The optimum filling ratio was determined using the method of critical pigment volume concentration (CPVC. The optimum filling ratio was found equal to 55%.

Mobile Inquiry Based Learning

NARCIS (Netherlands)

Specht, Marcus

2012-01-01

Specht, M. (2012, 8 November). Mobile Inquiry Based Learning. Presentation given at the Workshop "Mobile inquiry-based learning" at the Mobile Learning Day 2012 at the Fernuniversität Hagen, Hagen, Germany.

Carbon Based Nanotechnology: Review

Science.gov (United States)

Srivastava, Deepak; Saini, Subhash (Technical Monitor)

1999-01-01

This presentation reviews publicly available information related to carbon based nanotechnology. Topics covered include nanomechanics, carbon based electronics, nanodevice/materials applications, nanotube motors, nano-lithography and H2O storage in nanotubes.

Environmental Assessment: General Plan-Based Environmental Impact Analysis Process, Laughlin Air Force Base

Science.gov (United States)

2007-05-01

BASED ENVIROMENTAL IMPACT ANALYSIS PROCESS LAUGHLIN AIR FORCE BASE, TEXAS AGENCY: 47th Flying Training Wing (FTW), Laughlin Air Force Base (AFB), Texas...m3 micrograms per cubic meter US United States USACE United States Army Corp of Engineers USC United States Code USCB United States Census Bureau...effects and annoyance in that very few flight operations and ground engine runs occur between 2200 hours and 0700 hours. BMPs include restricting the

OLBS: Offline location based services

OpenAIRE

Coelho, P; Ana Aguiar; João Correia Lopes

2011-01-01

Most existing location-based services rely on ubiquitous connectivity to deliver location-based contents to the users. However, connectivity is not available anywhere at anytime even in urban centres. Underground, indoors, remote areas, and foreign countries are examples situations where users commonly do not have guaranteed connectivity but could profit from location-based contents. In this work, we propose an open platform for publishing, distributing and maintaining location-based contents...

A critique of the molecular target-based drug discovery paradigm based on principles of metabolic control: advantages of pathway-based discovery.

Science.gov (United States)

Hellerstein, Marc K

2008-01-01

Contemporary drug discovery and development (DDD) is dominated by a molecular target-based paradigm. Molecular targets that are potentially important in disease are physically characterized; chemical entities that interact with these targets are identified by ex vivo high-throughput screening assays, and optimized lead compounds enter testing as drugs. Contrary to highly publicized claims, the ascendance of this approach has in fact resulted in the lowest rate of new drug approvals in a generation. The primary explanation for low rates of new drugs is attrition, or the failure of candidates identified by molecular target-based methods to advance successfully through the DDD process. In this essay, I advance the thesis that this failure was predictable, based on modern principles of metabolic control that have emerged and been applied most forcefully in the field of metabolic engineering. These principles, such as the robustness of flux distributions, address connectivity relationships in complex metabolic networks and make it unlikely a priori that modulating most molecular targets will have predictable, beneficial functional outcomes. These same principles also suggest, however, that unexpected therapeutic actions will be common for agents that have any effect (i.e., that complexity can be exploited therapeutically). A potential operational solution (pathway-based DDD), based on observability rather than predictability, is described, focusing on emergent properties of key metabolic pathways in vivo. Recent examples of pathway-based DDD are described. In summary, the molecular target-based DDD paradigm is built on a naïve and misleading model of biologic control and is not heuristically adequate for advancing the mission of modern therapeutics. New approaches that take account of and are built on principles described by metabolic engineers are needed for the next generation of DDD.

ARAC terrain data base

International Nuclear Information System (INIS)

Walker, H.

1982-11-01

A terrain data base covering the continental United States at 500-meter resolution has been generated. Its function is to provide terrain data for input to mesoscale atmospheric models that are used as part of the Atmospheric Release Advisory Capability at Lawrence Livermore Laboratory (LLNL). The structure of the data base as it exists on the LLNL computer system is described. The data base has been written to tapes for transfer to other systems and the format of these tapes is also described

Reconsidering Community-based Retailing

OpenAIRE

Maughan, Rebecca; O'Driscoll, Aidan

2012-01-01

One of the areas with great potential for economic, social and environmental benefit is community-based retailing. The concept of community based retailing can incorporate a number of different tenets. We suggest that it is retailing that is based close to the community it serves, usually within the town or village centre rather than out-of-town locations, and which is composed of a diverse range of small and medium sized business that are often independently or co-operatively owned. These co...

The knowledge base of journalism

DEFF Research Database (Denmark)

Svith, Flemming

In this paper I propose the knowledge base as a fruitful way to apprehend journalism. With the claim that the majority of practice is anchored in knowledge – understood as 9 categories of rationales, forms and levels – this knowledge base appears as a contextual look at journalists’ knowledge......, and place. As an analytical framework, the knowledge base is limited to understand the practice of newspaper journalists, but, conversely, the knowledge base encompasses more general beginnings through the inclusion of overall structural relationships in the media and journalism and general theories...... on practice and knowledge. As the result of an abductive reasoning is a theory proposal, there is a need for more deductive approaches to test the validity of this knowledge base claim. It is thus relevant to investigate which rationales are included in the knowledge base of journalism, as the dimension does...

A CSP-Based Agent Modeling Framework for the Cougaar Agent-Based Architecture

Science.gov (United States)

Gracanin, Denis; Singh, H. Lally; Eltoweissy, Mohamed; Hinchey, Michael G.; Bohner, Shawn A.

2005-01-01

Cognitive Agent Architecture (Cougaar) is a Java-based architecture for large-scale distributed agent-based applications. A Cougaar agent is an autonomous software entity with behaviors that represent a real-world entity (e.g., a business process). A Cougaar-based Model Driven Architecture approach, currently under development, uses a description of system's functionality (requirements) to automatically implement the system in Cougaar. The Communicating Sequential Processes (CSP) formalism is used for the formal validation of the generated system. Two main agent components, a blackboard and a plugin, are modeled as CSP processes. A set of channels represents communications between the blackboard and individual plugins. The blackboard is represented as a CSP process that communicates with every agent in the collection. The developed CSP-based Cougaar modeling framework provides a starting point for a more complete formal verification of the automatically generated Cougaar code. Currently it is used to verify the behavior of an individual agent in terms of CSP properties and to analyze the corresponding Cougaar society.

Consumption-based Equity Valuation

DEFF Research Database (Denmark)

Bach, Christian; Christensen, Peter Ove

2013-01-01

the performance of the model with several implementations of standard valuation models, both in terms of absolute valuation errors, and in terms of the returns on simple investment strategies based on the differences between model and market prices in the respective valuation models. The CCAPM-based valuation...... model performs substantially better than the best performing standard valuation model when comparing absolute valuation errors. Both types of models are able to identify investment strategies with subsequent excess returns but also in this setting, the CCAPM-based valuation model outperforms...... residual income for risk in the numerator rather than through a risk-adjusted cost of equity in the denominator. The risk-adjustments are derived based on assumptions about the time-series properties of residual income returns and aggregate consumption rather than on historical stock returns. We compare...

Filmless versus film-based systems in radiographic examination costs: an activity-based costing method

Directory of Open Access Journals (Sweden)

Sase Yuji

2011-09-01

Full Text Available Abstract Background Since the shift from a radiographic film-based system to that of a filmless system, the change in radiographic examination costs and costs structure have been undetermined. The activity-based costing (ABC method measures the cost and performance of activities, resources, and cost objects. The purpose of this study is to identify the cost structure of a radiographic examination comparing a filmless system to that of a film-based system using the ABC method. Methods We calculated the costs of radiographic examinations for both a filmless and a film-based system, and assessed the costs or cost components by simulating radiographic examinations in a health clinic. The cost objects of the radiographic examinations included lumbar (six views, knee (three views, wrist (two views, and other. Indirect costs were allocated to cost objects using the ABC method. Results The costs of a radiographic examination using a filmless system are as follows: lumbar 2,085 yen; knee 1,599 yen; wrist 1,165 yen; and other 1,641 yen. The costs for a film-based system are: lumbar 3,407 yen; knee 2,257 yen; wrist 1,602 yen; and other 2,521 yen. The primary activities were "calling patient," "explanation of scan," "take photographs," and "aftercare" for both filmless and film-based systems. The cost of these activities cost represented 36.0% of the total cost for a filmless system and 23.6% of a film-based system. Conclusions The costs of radiographic examinations using a filmless system and a film-based system were calculated using the ABC method. Our results provide clear evidence that the filmless system is more effective than the film-based system in providing greater value services directly to patients.

Filmless versus film-based systems in radiographic examination costs: an activity-based costing method.

Science.gov (United States)

Muto, Hiroshi; Tani, Yuji; Suzuki, Shigemasa; Yokooka, Yuki; Abe, Tamotsu; Sase, Yuji; Terashita, Takayoshi; Ogasawara, Katsuhiko

2011-09-30

Since the shift from a radiographic film-based system to that of a filmless system, the change in radiographic examination costs and costs structure have been undetermined. The activity-based costing (ABC) method measures the cost and performance of activities, resources, and cost objects. The purpose of this study is to identify the cost structure of a radiographic examination comparing a filmless system to that of a film-based system using the ABC method. We calculated the costs of radiographic examinations for both a filmless and a film-based system, and assessed the costs or cost components by simulating radiographic examinations in a health clinic. The cost objects of the radiographic examinations included lumbar (six views), knee (three views), wrist (two views), and other. Indirect costs were allocated to cost objects using the ABC method. The costs of a radiographic examination using a filmless system are as follows: lumbar 2,085 yen; knee 1,599 yen; wrist 1,165 yen; and other 1,641 yen. The costs for a film-based system are: lumbar 3,407 yen; knee 2,257 yen; wrist 1,602 yen; and other 2,521 yen. The primary activities were "calling patient," "explanation of scan," "take photographs," and "aftercare" for both filmless and film-based systems. The cost of these activities cost represented 36.0% of the total cost for a filmless system and 23.6% of a film-based system. The costs of radiographic examinations using a filmless system and a film-based system were calculated using the ABC method. Our results provide clear evidence that the filmless system is more effective than the film-based system in providing greater value services directly to patients.

Enhancement of Edge-based Image Quality Measures Using Entropy for Histogram Equalization-based Contrast Enhancement Techniques

Directory of Open Access Journals (Sweden)

H. T. R. Kurmasha

2017-12-01

Full Text Available An Edge-based image quality measure (IQM technique for the assessment of histogram equalization (HE-based contrast enhancement techniques has been proposed that outperforms the Absolute Mean Brightness Error (AMBE and Entropy which are the most commonly used IQMs to evaluate Histogram Equalization based techniques, and also the two prominent fidelity-based IQMs which are Multi-Scale Structural Similarity (MSSIM and Information Fidelity Criterion-based (IFC measures. The statistical evaluation results show that the Edge-based IQM, which was designed for detecting noise artifacts distortion, has a Person Correlation Coefficient (PCC > 0.86 while the others have poor or fair correlation to human opinion, considering the Human Visual Perception (HVP. Based on HVP, this paper propose an enhancement to classic Edge-based IQM by taking into account the brightness saturation distortion which is the most prominent distortion in HE-based contrast enhancement techniques. It is tested and found to have significantly well correlation (PCC > 0.87, Spearman rank order correlation coefficient (SROCC > 0.92, Root Mean Squared Error (RMSE < 0.1054, and Outlier Ratio (OR = 0%.

Mindfulness-Based Stress Reduction

Science.gov (United States)

... R S T U V W X Y Z Mindfulness-Based Stress Reduction (MBSR) Information 6 Things You ... Disease and Dementia (12/20/13) Research Spotlights Mindfulness-Based Stress Reduction, Cognitive-Behavioral Therapy Shown To ...

Feature-Based and String-Based Models for Predicting RNA-Protein Interaction

Directory of Open Access Journals (Sweden)

Donald Adjeroh

2018-03-01

Full Text Available In this work, we study two approaches for the problem of RNA-Protein Interaction (RPI. In the first approach, we use a feature-based technique by combining extracted features from both sequences and secondary structures. The feature-based approach enhanced the prediction accuracy as it included much more available information about the RNA-protein pairs. In the second approach, we apply search algorithms and data structures to extract effective string patterns for prediction of RPI, using both sequence information (protein and RNA sequences, and structure information (protein and RNA secondary structures. This led to different string-based models for predicting interacting RNA-protein pairs. We show results that demonstrate the effectiveness of the proposed approaches, including comparative results against leading state-of-the-art methods.

Beyond Zero Based Budgeting.

Science.gov (United States)

Ogden, Daniel M., Jr.

1978-01-01

Suggests that the most practical budgeting system for most managers is a formalized combination of incremental and zero-based analysis because little can be learned about most programs from an annual zero-based budget. (Author/IRT)

WormBase

Data.gov (United States)

U.S. Department of Health & Human Services — WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible...

Health Physics Positions Data Base

International Nuclear Information System (INIS)

Kerr, G.D.; Borges, T.; Stafford, R.S.; Lu, P.Y.; Carter, D.

1992-05-01

The Health Physics Positions (HPPOS) Data Base of the Nuclear Regulatory Commission (NRC) is a collection of summaries of NRC staff positions on a wide range of topics in radiation protection (health physics). The bases for the data base are 247 original documents in the form of letters, memoranda, and excerpts from technical reports. The HPPOS Data Base was developed by the NRC Headquarters and Regional Offices to help ensure uniformity in inspections, enforcement, and licensing actions

Competency-based training: who benefits?

Science.gov (United States)

Brightwell, Alexandra; Grant, Janet

2013-02-01

Competency based training describes progression through training referenced to the demonstrated ability to perform certain tasks. In recent years, this has become the dominant curriculum model. We seek to examine who benefits from a competency based approach to medical education. For the regulators and service, the apparent advantage is in terms of apparent measurable accountability and flexibility. For assessors, the promise of competence based assessments in the workplace to provide a reliable and objective measurement of a trainee's performance has not been demonstrated in practice. For the doctor in training, there is very little evidence to show benefit from competency based training. Competency based training places emphasis on individual skills rather than overall learning experience thus risks diminishing the role of the trainee in the workplace. Any form of medical education that devalues workplace based learning will ultimately harm the profession and, in turn, patient care.

Quaternary alloys based on II-VI semiconductors

CERN Document Server

Tomashyk, Vasyl

2014-01-01

Systems Based on ZnSSystems Based on ZnSeSystems Based on ZnTeSystems Based on CdSSystems Based on CdSeSystems Based on CdTeSystems Based on HgSSystems Based on HgSeSystems Based on HgTeIndexReferences appear at the end of each chapter.

Strength-based leadership coaching in organizations an evidence-based guide to positive leadership development

CERN Document Server

MacKie, Doug

2016-01-01

Positive organizational psychology, with its focus on the identification and development of strengths, is a natural ally to executive development and leadership coaching. However, this approach is only just beginning to come to the attention of organizations and consequently, the research base for strength-based coaching is in its early stages of development. Strength-based Leadership Coaching in Organizations reviews strength-based approaches to positive leadership development and evaluates the evidence for their effectiveness, critically assesses their apparent distinctiveness and considers how strengths can be reliably assessed and developed in their organizational context. This book reviews key areas of leader and team development are reviewed and outlines and describes a model of strengths development in organizations. The application of strength-based leadership coaching will be discussed from the managerial and external perspective within the context of career stage, seniority, role challenges and orga...

A comparative study on the flow experience in web-based and text-based interaction environments.

Science.gov (United States)

Huang, Li-Ting; Chiu, Chen-An; Sung, Kai; Farn, Cheng-Kiang

2011-01-01

The purpose of this study was to explore a substantial phenomenon related to flow experiences (immersion) in text-based interaction systems. Most previous research emphasizes the effects of challenge/skill, focused attention, telepresence, web characteristics, and systems' interface design on users' flow experiences in online environments. However, text-based interaction systems without telepresence features and web characteristics still seem to create opportunities for flow experience. To explore this phenomenon, this study incorporates subject involvement and interpersonal interaction as critical antecedents into the model of flow experience, as well as considers the existence of telepresence. Results reveal that subject involvement, interpersonal interaction, and interactivity speed are critical to focused attention, which enhances users' immersion. With regard to the effect of telepresence, the perceived attractiveness of the interface is a significant facilitator determining users' immersion in web-based, rather than in text-based, interaction environments. Interactivity speed is unrelated to immersion in both web-based and text-based interaction environments. The influence of interpersonal involvement is diminished in web-based interaction environments. The implications and limitations of this study are discussed.

Risk-based configuration control

International Nuclear Information System (INIS)

Szikszai, T.

1997-01-01

The presentation discusses the following issues: The Configuration Control; The Risk-based Configuration Control (during power operation mode, and during shutdown mode). PSA requirements. Use of Risk-based Configuration Control System. Configuration Management (basic elements, benefits, information requirements)

Microbead agglutination based assays

KAUST Repository

Kodzius, Rimantas; Castro, David; Foulds, Ian G.; Parameswaran, Ash M.; Sumanpreet, K. Chhina

2013-01-01

We report a simple and rapid room temperature assay for point-of-care (POC) testing that is based on specific agglutination. Agglutination tests are based on aggregation of microbeads in the presence of a specific analyte thus enabling

Differentiating case-based learning from problem-based learning after a twoday introductory workshop on case-based learning

Directory of Open Access Journals (Sweden)

Aqil Mohammad Daher

2017-12-01

Full Text Available Background Considerable overlap exists between case-based learning (CBL and problem-based learning (PBL and differentiating between the two can be difficult for a lot of the academicians. Aims This study gauged the ability of members of medical school, familiar with a problem-based learning (PBL curriculum, to differentiate between case-based learning (CBL and PBL after a two-day workshop on CBL. Methods A questionnaire was distributed to all participants, attending the introductory course on CBL. It was designed to document the basic characteristics of the respondents, their preference for either CBL or PBL, their ability to recognize differences between CBL and PBL, and their overall perception of the course. Results Of the total workshop participants, 80.5 per cent returned the completed questionnaire. The mean age of the respondents was 44.12±12.31 years and women made up a slight majority. Majority favoured CBL over PBL and felt it was more clinical, emphasizes on self-directed learning, provides more opportunities for learning, permits in-depth exploration of cases, has structured environment and encourages the use of all learning resources. On the respondents’ ability to discriminate CBL from PBL, a weighted score of 39.9 per cent indicated a failure on the part of the respondents to correctly identify differences between CBL and PBL. Less than half opined that CBL was a worthwhile progression from PBL and about third would recommend CBL over PBL. Conclusion It seems that majority of the respondents failed to adequately differentiate between CBL and PBL and didn’t favour CBL over PBL.

Water-Based Pressure-Sensitive Paints

Science.gov (United States)

Jordan, Jeffrey D.; Watkins, A. Neal; Oglesby, Donald M.; Ingram, JoAnne L.

2006-01-01

Water-based pressure-sensitive paints (PSPs) have been invented as alternatives to conventional organic-solvent-based pressure-sensitive paints, which are used primarily for indicating distributions of air pressure on wind-tunnel models. Typically, PSPs are sprayed onto aerodynamic models after they have been mounted in wind tunnels. When conventional organic-solvent-based PSPs are used, this practice creates a problem of removing toxic fumes from inside the wind tunnels. The use of water-based PSPs eliminates this problem. The waterbased PSPs offer high performance as pressure indicators, plus all the advantages of common water-based paints (low toxicity, low concentrations of volatile organic compounds, and easy cleanup by use of water).

Paper based electronics platform

KAUST Repository

Nassar, Joanna Mohammad

2017-07-20

A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

36 CFR 1237.30 - How do agencies manage records on nitrocellulose-base and cellulose-acetate base film?

Science.gov (United States)

2010-07-01

... records on nitrocellulose-base and cellulose-acetate base film? 1237.30 Section 1237.30 Parks, Forests... and cellulose-acetate base film? (a) The nitrocellulose base, a substance akin to gun cotton, is chemically unstable and highly flammable. Agencies must handle nitrocellulose-base film (used in the...

Surface stress-based biosensors.

Science.gov (United States)

Sang, Shengbo; Zhao, Yuan; Zhang, Wendong; Li, Pengwei; Hu, Jie; Li, Gang

2014-01-15

Surface stress-based biosensors, as one kind of label-free biosensors, have attracted lots of attention in the process of information gathering and measurement for the biological, chemical and medical application with the development of technology and society. This kind of biosensors offers many advantages such as short response time (less than milliseconds) and a typical sensitivity at nanogram, picoliter, femtojoule and attomolar level. Furthermore, it simplifies sample preparation and testing procedures. In this work, progress made towards the use of surface stress-based biosensors for achieving better performance is critically reviewed, including our recent achievement, the optimally circular membrane-based biosensors and biosensor array. The further scientific and technological challenges in this field are also summarized. Critical remark and future steps towards the ultimate surface stress-based biosensors are addressed. Copyright © 2013 Elsevier B.V. All rights reserved.

Consumption-based Equity Valuation

DEFF Research Database (Denmark)

Bach, Christian; Christensen, Peter O.

2016-01-01

implementations of standard valuation models, both in terms of median absolute valuation errors (MAVE) and in terms of excess returns on simple investment strategies based on the differences between model and market prices. The CCAPM-based valuation model yields a significantly lower MAVE than the best performing...... standard valuation model. Both types of models can identify investment strategies with subsequent excess returns. The CCAPM-based valuation model yields time-series of realized hedge returns with more and higher positive returns and fewer and less negative returns compared with the time-series of realized...... through a risk-adjusted cost of equity in the denominator. The risk adjustments are derived based on assumptions about the time-series properties of residual income returns and aggregate consumption rather than on historical stock returns. We compare the performance of the model with several...

Research into Oil-based Colloidal-Graphite Lubricants for Forging of Al-based Alloys

International Nuclear Information System (INIS)

Petrov, A.; Petrov, P.; Petrov, M.

2011-01-01

The presented paper describes the topical problem in metal forging production. It deals with the choice of an optimal lubricant for forging of Al-based alloys. Within the scope of the paper, the properties of several oil-based colloidal-graphite lubricants were investigated. The physicochemical and technological properties of these lubricants are presented. It was found that physicochemical properties of lubricant compositions have an influence on friction coefficient value and quality of forgings.The ring compression method was used to estimate the friction coefficient value. Hydraulic press was used for the test. The comparative analysis of the investigated lubricants was carried out. The forging quality was estimated on the basis of production test. The practical recommendations were given to choose an optimal oil-based colloidal-graphite lubricant for isothermal forging of Al-based alloy.

Case base classification on digital mammograms: improving the performance of case base classifier

Science.gov (United States)

Raman, Valliappan; Then, H. H.; Sumari, Putra; Venkatesa Mohan, N.

2011-10-01

Breast cancer continues to be a significant public health problem in the world. Early detection is the key for improving breast cancer prognosis. The aim of the research presented here is in twofold. First stage of research involves machine learning techniques, which segments and extracts features from the mass of digital mammograms. Second level is on problem solving approach which includes classification of mass by performance based case base classifier. In this paper we build a case-based Classifier in order to diagnose mammographic images. We explain different methods and behaviors that have been added to the classifier to improve the performance of the classifier. Currently the initial Performance base Classifier with Bagging is proposed in the paper and it's been implemented and it shows an improvement in specificity and sensitivity.

Inverted base pavements: construction and performance

KAUST Repository

Papadopoulos, Efthymios

2017-05-11

Inverted base pavements involve a well-compacted granular aggregate base built between a thin asphalt concrete layer and a cement-treated base. Inverted base pavements can be constructed using conventional equipment and procedures but require proper quality control. This study reviews the extensive South African experience and case histories in the USA. Accumulating evidence suggests that inverted base pavements are a viable alternative and can outperform conventional pavements at a lower cost. Inverted base pavements rely on the complementary interaction between layers. The cement-treated base provides a stiff foundation for efficient compaction and constrains the deformation of the stress-sensitive granular aggregate base. The thin asphalt surface layer deforms as a membrane and develops low tensile stress. Additional large-scale field tests should be conducted to assess the performance of inverted base pavement designs in a wide range of conditions relevant to the USA.

Under What Conditions Do Rules-Based and Capability-Based Management Modes Dominate?

Directory of Open Access Journals (Sweden)

Lukas Michel

2018-04-01

Full Text Available Despite real changes in the work place and the negative consequences of prevailing hierarchical structures with rigid management systems, little attention has yet been paid to shifting management modes to accommodate the dynamics of the external environment, particularly when a firm’s operating environment demands a high degree of flexibility. Building on the resource-based view as a basis for competitive advantage, we posit that differences in the stability of an organization’s environment and the degree of managerial control explain variations in the management mode used in firms. Unlike other studies which mainly focus on either the dynamics of the external environment or management control, we have developed a theoretical model combining both streams of research, in a context frame to describe under what conditions firms engage in rules-based, change-based, engagement-based and capability-based management modes. To test our theoretical framework, we conducted a survey with 54 firms in various industries and nations on how their organizations cope with a dynamic environment and what management style they used in response. Our study reveals that the appropriate mode can be determined by analyzing purpose, motivation, knowledge and information, as well as the degree of complexity, volatility and uncertainty the firm is exposed to. With our framework, we attempt to advance the understanding of when organizations should adapt their management style to the changing business environment.

Seismic performance evaluation of an MR elastomer-based smart base isolation system using real-time hybrid simulation

International Nuclear Information System (INIS)

Eem, S H; Jung, H J; Koo, J H

2013-01-01

Recently, magneto-rheological (MR) elastomer-based base isolation systems have been actively studied as alternative smart base isolation systems because MR elastomers are capable of adjusting their modulus or stiffness depending on the magnitude of the applied magnetic field. By taking advantage of the MR elastomers’ stiffness-tuning ability, MR elastomer-based smart base isolation systems strive to alleviate limitations of existing smart base isolation systems as well as passive-type base isolators. Until now, research on MR elastomer-based base isolation systems primarily focused on characterization, design, and numerical evaluations of MR elastomer-based isolators, as well as experimental tests with simple structure models. However, their applicability to large civil structures has not been properly studied yet because it is quite challenging to numerically emulate the complex behavior of MR elastomer-based isolators and to conduct experiments with large-size structures. To address these difficulties, this study employs the real-time hybrid simulation technique, which combines physical testing and computational modeling. The primary goal of the current hybrid simulation study is to evaluate seismic performances of an MR elastomer-based smart base isolation system, particularly its adaptability to distinctly different seismic excitations. In the hybrid simulation, a single-story building structure (non-physical, computational model) is coupled with a physical testing setup for a smart base isolation system with associated components (such as laminated MR elastomers and electromagnets) installed on a shaking table. A series of hybrid simulations is carried out under two seismic excitations having different dominant frequencies. The results show that the proposed smart base isolation system outperforms the passive base isolation system in reducing the responses of the structure for the excitations considered in this study. (paper)

Home-based Healthcare Technology

DEFF Research Database (Denmark)

Verdezoto, Nervo

of these systems target a specific treatment or condition and might not be sufficient to support the care management work at home. Based on a case study approach, my research investigates home-based healthcare practices and how they can inform future design of home-based healthcare technology that better account......Sustaining daily, unsupervised healthcare activities in non-clinical settings such as the private home can challenge, among others, older adults. To support such unsupervised care activities, an increasingly number of reminders and monitoring systems are being designed. However, most...

Risk-based safety indicators

International Nuclear Information System (INIS)

Sedlak, J.

2001-12-01

The report is structured as follows: 1. Risk-based safety indicators: Typology of risk-based indicators (RBIs); Tools for defining RBIs; Requirements for the PSA model; Data sources for RBIs; Types of risks monitored; RBIs and operational safety indicators; Feedback from operating experience; PSO model modification for RBIs; RBI categorization; RBI assessment; RBI applications; Suitable RBI applications. 2. Proposal for risk-based indicators: Acquiring information from operational experience; Method of acquiring safety relevance coefficients for the systems from a PSA model; Indicator definitions; On-line indicators. 3. Annex: Application of RBIs worldwide. (P.A.)

No evidence-based restoration without a sound evidence base: a reply to Guldemond et al.

CSIR Research Space (South Africa)

Ntshotsho, P

2012-03-01

Full Text Available Evidence-based practice is not possible without an evidence base. Guldemond et al. confuse our attempt at assessing the status of the evidence base of restoration programs in South Africa with attempting to assess whether restoration is evidence...

A REGION-BASED MULTI-SCALE APPROACH FOR OBJECT-BASED IMAGE ANALYSIS

Directory of Open Access Journals (Sweden)

T. Kavzoglu

2016-06-01

Full Text Available Within the last two decades, object-based image analysis (OBIA considering objects (i.e. groups of pixels instead of pixels has gained popularity and attracted increasing interest. The most important stage of the OBIA is image segmentation that groups spectrally similar adjacent pixels considering not only the spectral features but also spatial and textural features. Although there are several parameters (scale, shape, compactness and band weights to be set by the analyst, scale parameter stands out the most important parameter in segmentation process. Estimating optimal scale parameter is crucially important to increase the classification accuracy that depends on image resolution, image object size and characteristics of the study area. In this study, two scale-selection strategies were implemented in the image segmentation process using pan-sharped Qickbird-2 image. The first strategy estimates optimal scale parameters for the eight sub-regions. For this purpose, the local variance/rate of change (LV-RoC graphs produced by the ESP-2 tool were analysed to determine fine, moderate and coarse scales for each region. In the second strategy, the image was segmented using the three candidate scale values (fine, moderate, coarse determined from the LV-RoC graph calculated for whole image. The nearest neighbour classifier was applied in all segmentation experiments and equal number of pixels was randomly selected to calculate accuracy metrics (overall accuracy and kappa coefficient. Comparison of region-based and image-based segmentation was carried out on the classified images and found that region-based multi-scale OBIA produced significantly more accurate results than image-based single-scale OBIA. The difference in classification accuracy reached to 10% in terms of overall accuracy.

Individual versus Interactive Task-Based Performance through Voice-Based Computer-Mediated Communication

Science.gov (United States)

Granena, Gisela

2016-01-01

Interaction is a necessary condition for second language (L2) learning (Long, 1980, 1996). Research in computer-mediated communication has shown that interaction opportunities make learners pay attention to form in a variety of ways that promote L2 learning. This research has mostly investigated text-based rather than voice-based interaction. The…

Condition based spare parts supply

NARCIS (Netherlands)

Lin, X.; Basten, Robertus Johannes Ida; Kranenburg, A.A.; van Houtum, Geert-Jan

2012-01-01

We consider a spare parts stock point that serves an installed base of machines. Each machine contains the same critical component, whose degradation behavior is described by a Markov process. We consider condition based spare parts supply, and show that an optimal, condition based inventory policy

Lunar resource base

Science.gov (United States)

Pulley, John; Wise, Todd K.; Roy, Claude; Richter, Phil

A lunar base that exploits local resources to enhance the productivity of a total SEI scenario is discussed. The goals were to emphasize lunar science and to land men on Mars in 2016 using significant amounts of lunar resources. It was assumed that propulsion was chemical and the surface power was non-nuclear. Three phases of the base build-up are outlined, the robotic emplacement of the first elements is detailed and a discussion of future options is included.

Game-based telerehabilitation.

Science.gov (United States)

Lange, B; Flynn, Sheryl M; Rizzo, A A

2009-03-01

This article summarizes the recent accomplishments and current challenges facing game-based virtual reality (VR) telerehabilitation. Specifically this article addresses accomplishments relative to realistic practice scenarios, part to whole practice, objective measurement of performance and progress, motivation, low cost, interaction devices and game design. Furthermore, a description of the current challenges facing game based telerehabilitation including the packaging, internet capabilities and access, data management, technical support, privacy protection, seizures, distance trials, scientific scrutiny and support from insurance companies.

Knowledge collaborative incentive based on inter-organizational cooperative innovation of project-based supply chain

Directory of Open Access Journals (Sweden)

Guangdong Wu

2013-09-01

Full Text Available Purpose: Within project-based supply chain inter-organizational cooperative innovation, the achievement of project value-adding reflects by factors such as project-based organizational effect level, the relationship between project cooperative innovation objectives etc. The purpose is to provide a reliable reference for the contractor reasonably allocate the effect level and resources between the knowledge input and innovation stage and realize the knowledge collaboration for project-based supply chain. Design/methodology/approach: Based on the assumption of equal cooperation between project-based organizations, from the view of maximizing project value-adding and the relationship of effect cost between knowledge input and innovation stage in consideration, the knowledge collaborative incentive model for project-based supply chain inter-organizational cooperative innovation was established, and solved through the first-order and second-order approach, then the digital simulation and example analysis were presented. Findings: The results show that, the project management enterprise resorted to adjust project knowledge collaboration incentive intensity and implemented knowledge input-innovation coordinative incentive strategy, not only could achieve project value-adding maximization, but also could realize net earnings Pareto improvement between project management enterprise and contractor. Research limitations/implications: To simplify the knowledge flow among project-based organizations, the knowledge flow in the model hypothesis is presented as knowledge input and knowledge innovation stage, thus it may affect the final analysis results. Originality/value: In construction project practice, knowledge is become more and more important to achieve project value-adding. The research can provide a theoretical guideline for the project-based organizations, such as the contractor, the owner, especially how to utilize their core knowledge.

Project- Based Learning and Problem-Based Learning: Are They Effective to Improve Student's Thinking Skills?

OpenAIRE

Anazifa, R. D; Djukri, D

2017-01-01

The study aims at finding (1) the effect of project-based learning and problem-based learning on student's creativity and critical thinking and (2) the difference effect of project-based learning and problem-based learning on student's creativity and critical thinking. This study is quasi experiment using non-equivalent control-group design. Research population of this study was all classes in eleventh grade of mathematics and natural science program of SMA N 1 Temanggung. The participants we...

A super base station based centralized network architecture for 5G mobile communication systems

Directory of Open Access Journals (Sweden)

Manli Qian

2015-04-01

Full Text Available To meet the ever increasing mobile data traffic demand, the mobile operators are deploying a heterogeneous network with multiple access technologies and more and more base stations to increase the network coverage and capacity. However, the base stations are isolated from each other, so different types of radio resources and hardware resources cannot be shared and allocated within the overall network in a cooperative way. The mobile operators are thus facing increasing network operational expenses and a high system power consumption. In this paper, a centralized radio access network architecture, referred to as the super base station (super BS, is proposed, as a possible solution for an energy-efficient fifth-generation (5G mobile system. The super base station decouples the logical functions and physical entities of traditional base stations, so different types of system resources can be horizontally shared and statistically multiplexed among all the virtual base stations throughout the entire system. The system framework and main functionalities of the super BS are described. Some key technologies for system implementation, i.e., the resource pooling, real-time virtualization, adaptive hardware resource allocation are also highlighted.

Novel density-based and hierarchical density-based clustering algorithms for uncertain data.

Science.gov (United States)

Zhang, Xianchao; Liu, Han; Zhang, Xiaotong

2017-09-01

Uncertain data has posed a great challenge to traditional clustering algorithms. Recently, several algorithms have been proposed for clustering uncertain data, and among them density-based techniques seem promising for handling data uncertainty. However, some issues like losing uncertain information, high time complexity and nonadaptive threshold have not been addressed well in the previous density-based algorithm FDBSCAN and hierarchical density-based algorithm FOPTICS. In this paper, we firstly propose a novel density-based algorithm PDBSCAN, which improves the previous FDBSCAN from the following aspects: (1) it employs a more accurate method to compute the probability that the distance between two uncertain objects is less than or equal to a boundary value, instead of the sampling-based method in FDBSCAN; (2) it introduces new definitions of probability neighborhood, support degree, core object probability, direct reachability probability, thus reducing the complexity and solving the issue of nonadaptive threshold (for core object judgement) in FDBSCAN. Then, we modify the algorithm PDBSCAN to an improved version (PDBSCANi), by using a better cluster assignment strategy to ensure that every object will be assigned to the most appropriate cluster, thus solving the issue of nonadaptive threshold (for direct density reachability judgement) in FDBSCAN. Furthermore, as PDBSCAN and PDBSCANi have difficulties for clustering uncertain data with non-uniform cluster density, we propose a novel hierarchical density-based algorithm POPTICS by extending the definitions of PDBSCAN, adding new definitions of fuzzy core distance and fuzzy reachability distance, and employing a new clustering framework. POPTICS can reveal the cluster structures of the datasets with different local densities in different regions better than PDBSCAN and PDBSCANi, and it addresses the issues in FOPTICS. Experimental results demonstrate the superiority of our proposed algorithms over the existing

Parallel Representation of Value-Based and Finite State-Based Strategies in the Ventral and Dorsal Striatum.

Directory of Open Access Journals (Sweden)

Makoto Ito

2015-11-01

Full Text Available Previous theoretical studies of animal and human behavioral learning have focused on the dichotomy of the value-based strategy using action value functions to predict rewards and the model-based strategy using internal models to predict environmental states. However, animals and humans often take simple procedural behaviors, such as the "win-stay, lose-switch" strategy without explicit prediction of rewards or states. Here we consider another strategy, the finite state-based strategy, in which a subject selects an action depending on its discrete internal state and updates the state depending on the action chosen and the reward outcome. By analyzing choice behavior of rats in a free-choice task, we found that the finite state-based strategy fitted their behavioral choices more accurately than value-based and model-based strategies did. When fitted models were run autonomously with the same task, only the finite state-based strategy could reproduce the key feature of choice sequences. Analyses of neural activity recorded from the dorsolateral striatum (DLS, the dorsomedial striatum (DMS, and the ventral striatum (VS identified significant fractions of neurons in all three subareas for which activities were correlated with individual states of the finite state-based strategy. The signal of internal states at the time of choice was found in DMS, and for clusters of states was found in VS. In addition, action values and state values of the value-based strategy were encoded in DMS and VS, respectively. These results suggest that both the value-based strategy and the finite state-based strategy are implemented in the striatum.

Parallel Representation of Value-Based and Finite State-Based Strategies in the Ventral and Dorsal Striatum.

Science.gov (United States)

Ito, Makoto; Doya, Kenji

2015-11-01

Previous theoretical studies of animal and human behavioral learning have focused on the dichotomy of the value-based strategy using action value functions to predict rewards and the model-based strategy using internal models to predict environmental states. However, animals and humans often take simple procedural behaviors, such as the "win-stay, lose-switch" strategy without explicit prediction of rewards or states. Here we consider another strategy, the finite state-based strategy, in which a subject selects an action depending on its discrete internal state and updates the state depending on the action chosen and the reward outcome. By analyzing choice behavior of rats in a free-choice task, we found that the finite state-based strategy fitted their behavioral choices more accurately than value-based and model-based strategies did. When fitted models were run autonomously with the same task, only the finite state-based strategy could reproduce the key feature of choice sequences. Analyses of neural activity recorded from the dorsolateral striatum (DLS), the dorsomedial striatum (DMS), and the ventral striatum (VS) identified significant fractions of neurons in all three subareas for which activities were correlated with individual states of the finite state-based strategy. The signal of internal states at the time of choice was found in DMS, and for clusters of states was found in VS. In addition, action values and state values of the value-based strategy were encoded in DMS and VS, respectively. These results suggest that both the value-based strategy and the finite state-based strategy are implemented in the striatum.

New Mexico Geothermal Data Base

International Nuclear Information System (INIS)

Witcher, J.C.; Whittier, J.; Morgan, R.

1990-01-01

This paper reports on the New Mexico Geothermal Data Base (NMGDB) which is a comprehensive public-domain data base of low-temperature geothermal resource information for New Mexico that is designed to assist researchers and developers. A broad range of geoscience, engineering, climatic, economic, and land status information are complied in the dBASE III PLUS data base management system for use on an IBM or IBM-compatible personal computer. A user friendly menu format with on-screen prompts allows easy and convenient use

Development and Construction of the Multimedia Web-Based Courses Based on ASP

Science.gov (United States)

Wang, Yu; Liu, Jianbo

2011-01-01

With the quick development of internet and computer technology, more and more information acquirers begin to more depend on the network, and for the transmission route of knowledge, the advantageous state of web-based courses becomes more and more obvious. The support of modern education technology for the web-based courses would gradually replace…

Case-based medical informatics

Directory of Open Access Journals (Sweden)

Arocha José F

2004-11-01

Full Text Available Abstract Background The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four interconnected modalities of knowledge. In addition to the traditional differentiation between implicit and explicit knowledge we outline the concepts of general and individual knowledge. We connect general knowledge with the "frame problem," a fundamental issue of artificial intelligence, and individual knowledge with another important paradigm of artificial intelligence, case-based reasoning, a method of individual knowledge processing that aims at solving new problems based on the solutions to similar past problems. We outline the fundamental differences between Medical Informatics and theoretical sciences and propose that Medical Informatics research should advance individual knowledge processing (case-based reasoning and that natural language processing research is an important step towards this goal that may have ethical implications for patient-centered health medicine. Discussion We focus on fundamental aspects of decision-making, which connect human expertise with individual knowledge processing. We continue with a knowledge spectrum perspective on biomedical knowledge and conclude that case-based reasoning is the paradigm that can advance towards personalized healthcare and that can enable the education of patients and providers. We center the discussion on formal methods of knowledge representation around the frame problem. We propose a context-dependent view on the notion of "meaning" and advocate the need for case-based reasoning research and natural language processing. In the context of memory based knowledge processing, pattern recognition, comparison and analogy-making, we conclude that while humans seem to naturally support the case-based reasoning paradigm (memory of past experiences

Package-based software development

NARCIS (Netherlands)

Jonge, de M.; Chroust, G.; Hofer, C.

2003-01-01

The main goal of component-based software engineering is to decrease development time and development costs of software systems, by reusing prefabricated building blocks. Here we focus on software reuse within the implementation of such component-based applications, and on the corresponding software

Higher-dimensional orbital-angular-momentum-based quantum key distribution with mutually unbiased bases

CSIR Research Space (South Africa)

Mafu, M

2013-09-01

Full Text Available We present an experimental study of higher-dimensional quantum key distribution protocols based on mutually unbiased bases, implemented by means of photons carrying orbital angular momentum. We perform (d + 1) mutually unbiased measurements in a...

Building SDN-Based Agricultural Vehicular Sensor Networks Based on Extended Open vSwitch.

Science.gov (United States)

Huang, Tao; Yan, Siyu; Yang, Fan; Pan, Tian; Liu, Jiang

2016-01-19

Software-defined vehicular sensor networks in agriculture, such as autonomous vehicle navigation based on wireless multi-sensor networks, can lead to more efficient precision agriculture. In SDN-based vehicle sensor networks, the data plane is simplified and becomes more efficient by introducing a centralized controller. However, in a wireless environment, the main controller node may leave the sensor network due to the dynamic topology change or the unstable wireless signal, leaving the rest of network devices without control, e.g., a sensor node as a switch may forward packets according to stale rules until the controller updates the flow table entries. To solve this problem, this paper proposes a novel SDN-based vehicular sensor networks architecture which can minimize the performance penalty of controller connection loss. We achieve this by designing a connection state detection and self-learning mechanism. We build prototypes based on extended Open vSwitch and Ryu. The experimental results show that the recovery time from controller connection loss is under 100 ms and it keeps rule updating in real time with a stable throughput. This architecture enhances the survivability and stability of SDN-based vehicular sensor networks in precision agriculture.

Building SDN-Based Agricultural Vehicular Sensor Networks Based on Extended Open vSwitch

Directory of Open Access Journals (Sweden)

Tao Huang

2016-01-01

Full Text Available Software-defined vehicular sensor networks in agriculture, such as autonomous vehicle navigation based on wireless multi-sensor networks, can lead to more efficient precision agriculture. In SDN-based vehicle sensor networks, the data plane is simplified and becomes more efficient by introducing a centralized controller. However, in a wireless environment, the main controller node may leave the sensor network due to the dynamic topology change or the unstable wireless signal, leaving the rest of network devices without control, e.g., a sensor node as a switch may forward packets according to stale rules until the controller updates the flow table entries. To solve this problem, this paper proposes a novel SDN-based vehicular sensor networks architecture which can minimize the performance penalty of controller connection loss. We achieve this by designing a connection state detection and self-learning mechanism. We build prototypes based on extended Open vSwitch and Ryu. The experimental results show that the recovery time from controller connection loss is under 100 ms and it keeps rule updating in real time with a stable throughput. This architecture enhances the survivability and stability of SDN-based vehicular sensor networks in precision agriculture.

Building SDN-Based Agricultural Vehicular Sensor Networks Based on Extended Open vSwitch

Science.gov (United States)

Huang, Tao; Yan, Siyu; Yang, Fan; Pan, Tian; Liu, Jiang

2016-01-01

Software-defined vehicular sensor networks in agriculture, such as autonomous vehicle navigation based on wireless multi-sensor networks, can lead to more efficient precision agriculture. In SDN-based vehicle sensor networks, the data plane is simplified and becomes more efficient by introducing a centralized controller. However, in a wireless environment, the main controller node may leave the sensor network due to the dynamic topology change or the unstable wireless signal, leaving the rest of network devices without control, e.g., a sensor node as a switch may forward packets according to stale rules until the controller updates the flow table entries. To solve this problem, this paper proposes a novel SDN-based vehicular sensor networks architecture which can minimize the performance penalty of controller connection loss. We achieve this by designing a connection state detection and self-learning mechanism. We build prototypes based on extended Open vSwitch and Ryu. The experimental results show that the recovery time from controller connection loss is under 100 ms and it keeps rule updating in real time with a stable throughput. This architecture enhances the survivability and stability of SDN-based vehicular sensor networks in precision agriculture. PMID:26797616

Nanoswitches based on DNA base pairs: why adenine-thymine is less suitable than guanine-cytosine

NARCIS (Netherlands)

Fonseca Guerra, C.; van der Wijst, T.; Bickelhaupt, F.M.

2006-01-01

Substituted Watson-Crick guanine-cytosine (GC) base pairs were recently shown to yield robust three-state nanoswitches. Here, we address the question: Can such supramolecular switches also be based on Watson-Crick adenine-thymine (AT) base pairs? We have theoretically analyzed AT pairs in which

Cage-based performance capture

CERN Document Server

Savoye, Yann

2014-01-01

Nowadays, highly-detailed animations of live-actor performances are increasingly easier to acquire and 3D Video has reached considerable attentions in visual media production. In this book, we address the problem of extracting or acquiring and then reusing non-rigid parametrization for video-based animations. At first sight, a crucial challenge is to reproduce plausible boneless deformations while preserving global and local captured properties of dynamic surfaces with a limited number of controllable, flexible and reusable parameters. To solve this challenge, we directly rely on a skin-detached dimension reduction thanks to the well-known cage-based paradigm. First, we achieve Scalable Inverse Cage-based Modeling by transposing the inverse kinematics paradigm on surfaces. Thus, we introduce a cage inversion process with user-specified screen-space constraints. Secondly, we convert non-rigid animated surfaces into a sequence of optimal cage parameters via Cage-based Animation Conversion. Building upon this re...

Bayesian based Diagnostic Model for Condition based Maintenance of Offshore Wind Farms

DEFF Research Database (Denmark)

Asgarpour, Masoud; Sørensen, John Dalsgaard

2018-01-01

Operation and maintenance costs are a major contributor to the Levelized Cost of Energy for electricity produced by offshore wind and can be significantly reduced if existing corrective actions are performed as efficiently as possible and if future corrective actions are avoided by performing...... sufficient preventive actions. This paper presents an applied and generic diagnostic model for fault detection and condition based maintenance of offshore wind components. The diagnostic model is based on two probabilistic matrices; first, a confidence matrix, representing the probability of detection using...... for a wind turbine component based on vibration, temperature, and oil particle fault detection methods. The last part of the paper will have a discussion of the case study results and present conclusions....

Evidence-based quantification of uncertainties induced via simulation-based modeling

International Nuclear Information System (INIS)

Riley, Matthew E.

2015-01-01

The quantification of uncertainties in simulation-based modeling traditionally focuses upon quantifying uncertainties in the parameters input into the model, referred to as parametric uncertainties. Often neglected in such an approach are the uncertainties induced by the modeling process itself. This deficiency is often due to a lack of information regarding the problem or the models considered, which could theoretically be reduced through the introduction of additional data. Because of the nature of this epistemic uncertainty, traditional probabilistic frameworks utilized for the quantification of uncertainties are not necessarily applicable to quantify the uncertainties induced in the modeling process itself. This work develops and utilizes a methodology – incorporating aspects of Dempster–Shafer Theory and Bayesian model averaging – to quantify uncertainties of all forms for simulation-based modeling problems. The approach expands upon classical parametric uncertainty approaches, allowing for the quantification of modeling-induced uncertainties as well, ultimately providing bounds on classical probability without the loss of epistemic generality. The approach is demonstrated on two different simulation-based modeling problems: the computation of the natural frequency of a simple two degree of freedom non-linear spring mass system and the calculation of the flutter velocity coefficient for the AGARD 445.6 wing given a subset of commercially available modeling choices. - Highlights: • Modeling-induced uncertainties are often mishandled or ignored in the literature. • Modeling-induced uncertainties are epistemic in nature. • Probabilistic representations of modeling-induced uncertainties are restrictive. • Evidence theory and Bayesian model averaging are integrated. • Developed approach is applicable for simulation-based modeling problems

Radiolysis of nucleosides in aqueous solutions: base liberation by the base attack mechanism

International Nuclear Information System (INIS)

Fujita, S.

1984-01-01

On the radiolysis of uridine and some other nucleosides in aqueous solution, a pH-dependent liberation of uracil or the corresponding base was found. e - sub(aq) and HOsup(anion radicals) 2 gave no freed bases, although many oxidizing radicals, including OH, Clsup(anion radicals) 2 , Brsup(anion radicals) 2 , (CNS)sup(anion radicals) 2 and SOsup(anion radicals) 4 , did cause the release of unaltered bases, depending on the pH of the solutions. The base yields were generally high at pH >= 11, with the exception of SOsup(anion radicals) 4 , which gave a rather high yield of uracil (from uridine) even in the pH region of - , present at high pH as the dissociated form of OH, may act partly as an oxidizing radical. A plausible mechanism of 3 1 -radical formation is discussed. (author)

Development of web-based reliability data base platform

International Nuclear Information System (INIS)

Hwang, Seok Won; Lee, Chang Ju; Sung, Key Yong

2004-01-01

Probabilistic safety assessment (PSA) is a systematic technique which estimates the degree of risk impacts to the public due to an accident scenario. Estimating the occurrence frequencies and consequences of potential scenarios requires a thorough analysis of the accident details and all fundamental parameters. The robustness of PSA to check weaknesses in a design and operation will allow a better informed and balanced decision to be reached. The fundamental parameters for PSA, such as the component failure rates, should be estimated under the condition of steady collection of the evidence throughout the operational period. However, since any single plant data does not sufficiently enough to provide an adequate PSA result, in actual, the whole operating data was commonly used to estimate the reliability parameters for the same type of components. The reliability data of any component type consists of two categories; the generic that is based on the operating experiences of whole plants, and the plant-specific that is based on the operation of a specific plant of interest. The generic data is highly essential for new or recently-built nuclear power plants (NPPs). Generally, the reliability data base may be categorized into the component reliability, initiating event frequencies, human performance, and so on. Among these data, the component reliability seems a key element because it has the most abundant population. Therefore, the component reliability data is essential for taking a part in the quantification of accident sequences because it becomes an input of various basic events which consists of the fault tree

An investigation of care-based vs. rule-based morality in frontotemporal dementia, Alzheimer's disease, and healthy controls.

Science.gov (United States)

Carr, Andrew R; Paholpak, Pongsatorn; Daianu, Madelaine; Fong, Sylvia S; Mather, Michelle; Jimenez, Elvira E; Thompson, Paul; Mendez, Mario F

2015-11-01

Behavioral changes in dementia, especially behavioral variant frontotemporal dementia (bvFTD), may result in alterations in moral reasoning. Investigators have not clarified whether these alterations reflect differential impairment of care-based vs. rule-based moral behavior. This study investigated 18 bvFTD patients, 22 early onset Alzheimer's disease (eAD) patients, and 20 healthy age-matched controls on care-based and rule-based items from the Moral Behavioral Inventory and the Social Norms Questionnaire, neuropsychological measures, and magnetic resonance imaging (MRI) regions of interest. There were significant group differences with the bvFTD patients rating care-based morality transgressions less severely than the eAD group and rule-based moral behavioral transgressions more severely than controls. Across groups, higher care-based morality ratings correlated with phonemic fluency on neuropsychological tests, whereas higher rule-based morality ratings correlated with increased difficulty set-shifting and learning new rules to tasks. On neuroimaging, severe care-based reasoning correlated with cortical volume in right anterior temporal lobe, and rule-based reasoning correlated with decreased cortical volume in the right orbitofrontal cortex. Together, these findings suggest that frontotemporal disease decreases care-based morality and facilitates rule-based morality possibly from disturbed contextual abstraction and set-shifting. Future research can examine whether frontal lobe disorders and bvFTD result in a shift from empathic morality to the strong adherence to conventional rules. Published by Elsevier Ltd.

Iron-based superconductivity

CERN Document Server

Johnson, Peter D; Yin, Wei-Guo

2015-01-01

This volume presents an in-depth review of experimental and theoretical studies on the newly discovered Fe-based superconductors.  Following the Introduction, which places iron-based superconductors in the context of other unconventional superconductors, the book is divided into three sections covering sample growth, experimental characterization, and theoretical understanding.  To understand the complex structure-property relationships of these materials, results from a wide range of experimental techniques and theoretical approaches are described that probe the electronic and magnetic proper

Inkjet-based micromanufacturing

CERN Document Server

Korvink, Jan G; Shin, Dong-Youn; Brand, Oliver; Fedder, Gary K; Hierold, Christofer; Tabata, Osamu

2012-01-01

Inkjet-based Micromanufacturing Inkjet technology goes way beyond putting ink on paper: it enables simpler, faster and more reliable manufacturing processes in the fields of micro- and nanotechnology. Modern inkjet heads are per se precision instruments that deposit droplets of fluids on a variety of surfaces in programmable, repeating patterns, allowing, after suitable modifications and adaptations, the manufacturing of devices such as thin-film transistors, polymer-based displays and photovoltaic elements. Moreover, inkjet technology facilitates the large-scale production of flexible RFID tr

Problem-based learning and radiology

International Nuclear Information System (INIS)

Thurley, P.; Dennick, R.

2008-01-01

The Royal College of Radiologists recently published documents setting out guidelines to improve the teaching of radiology to medical students. These included recommendations that clinicians who teach radiology should be aware of newer educational techniques, such as problem-based learning, and should be involved in the development of curricula and assessment in medical schools. This review aims to introduce the educational theories behind problem-based learning and describe how a problem-based learning tutorial is run. The relevance of problem-based learning to radiology and the potential advantages and disadvantages are discussed

On Tree-Based Phylogenetic Networks.

Science.gov (United States)

Zhang, Louxin

2016-07-01

A large class of phylogenetic networks can be obtained from trees by the addition of horizontal edges between the tree edges. These networks are called tree-based networks. We present a simple necessary and sufficient condition for tree-based networks and prove that a universal tree-based network exists for any number of taxa that contains as its base every phylogenetic tree on the same set of taxa. This answers two problems posted by Francis and Steel recently. A byproduct is a computer program for generating random binary phylogenetic networks under the uniform distribution model.

ICT-based or ICT-centric?

DEFF Research Database (Denmark)

Sørensen, Jannick Kirk

2016-01-01

Through a logbook-based self-observation of an ICT-based service journey, the failure and the co-created recovery of the ICT-based service encounter is analysed. The analysis shows the limitations of both traditional affordances-based analyses of user interaction, as well as Dourish’s (2001......) ‘embodied interaction’ framework. Two new categories of service encounters are subsequently suggested: 1) ‘cognitively dominated service encounters’ that characterizes types of service encounters where the customer’s reasoning plays a central part in the service encounter, and 2) ‘ICT-centric’ service...

Case-Base Maintenance for CCBR-Based Process Evolution

NARCIS (Netherlands)

Weber, B.; Reichert, M.U.; Wild, W.; Roth-Berghofer, T.; Göker, M.H.; Güvenir, H.A.

2006-01-01

The success of a company more and more depends on its ability to flexibly and quickly react to changes. Combining process management techniques and conversational case-based reasoning (CCBR) allows for flexibly aligning the business processes to new requirements by providing integrated process life

Agent-Based Modeling of Day-Ahead Real Time Pricing in a Pool-Based Electricity Market

Directory of Open Access Journals (Sweden)

Sh. Yousefi

2011-09-01

Full Text Available In this paper, an agent-based structure of the electricity retail market is presented based on which day-ahead (DA energy procurement for customers is modeled. Here, we focus on operation of only one Retail Energy Provider (REP agent who purchases energy from DA pool-based wholesale market and offers DA real time tariffs to a group of its customers. As a model of customer response to the offered real time prices, an hourly acceptance function is proposed in order to represent the hourly changes in the customer’s effective demand according to the prices. Here, Q-learning (QL approach is applied in day-ahead real time pricing for the customers enabling the REP agent to discover which price yields the most benefit through a trial-and-error search. Numerical studies are presented based on New England day-ahead market data which include comparing the results of RTP based on QL approach with that of genetic-based pricing.

A Multilayer Perceptron-Based Impulsive Noise Detector with Application to Power-Line-Based Sensor Networks

KAUST Repository

Chien, Ying-Ren

2018-04-10

For power-line-based sensor networks, impulsive noise (IN) will dramatically degrade the data transmission rate in the power line. In this paper, we present a multilayer perceptron (MLP)-based approach to detect IN in orthogonal frequency-division multiplexing (OFDM)-based baseband power line communications (PLCs). Combining the MLP-based IN detection method with the outlier detection theory allows more accurate identification of the harmful residual IN. For OFDM-based PLC systems, the high peak-to-average power ratio (PAPR) of the received signal makes detection of harmful residual IN more challenging. The detection mechanism works in an iterative receiver that contains a pre-IN mitigation and a post-IN mitigation. The pre-IN mitigation is meant to null the stronger portion of IN, while the post-IN mitigation suppresses the residual portion of IN using an iterative process. Compared with previously reported IN detectors, the simulation results show that our MLP-based IN detector improves the resulting bit error rate (BER) performance.

European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

DEFF Research Database (Denmark)

Aldecoa, César; Bettelli, Gabriella; Bilotta, Federico

2017-01-01

The purpose of this guideline is to present evidence-based and consensus-based recommendations for the prevention and treatment of postoperative delirium. The cornerstones of the guideline are the preoperative identification and handling of patients at risk, adequate intraoperative care, postoper...

European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

NARCIS (Netherlands)

Aldecoa, César; Bettelli, Gabriella; Bilotta, Federico; Sanders, Robert D.; Audisio, Riccardo; Borozdina, Anastasia; Cherubini, Antonio; Jones, Christina; Kehlet, Henrik; Maclullich, Alasdair; Radtke, Finn; Riese, Florian; Slooter, Arjen J C; Veyckemans, Francis; Kramer, Sylvia; Neuner, Bruno; Weiss, Bjoern; Spies, Claudia D.

2017-01-01

The purpose of this guideline is to present evidence-based and consensus-based recommendations for the prevention and treatment of postoperative delirium. The cornerstones of the guideline are the preoperative identification and handling of patients at risk, adequate intraoperative care,

Spinocerebellar ataxia type 2 neurodegeneration differentially affects error-based and strategic-based visuomotor learning.

Science.gov (United States)

Vaca-Palomares, Israel; Díaz, Rosalinda; Rodríguez-Labrada, Roberto; Medrano-Montero, Jacqeline; Vázquez-Mojena, Yaimé; Velázquez-Pérez, Luis; Fernandez-Ruiz, Juan

2013-12-01

There are different types of visuomotor learning. Among the most studied is motor error-based learning where the sign and magnitude of the error are used to update motor commands. However, there are other instances where individuals show visuomotor learning even if the sign or magnitude of the error is precluded. Studies with patients suggest that the former learning is impaired after cerebellar lesions, while basal ganglia lesions disrupt the latter. Nevertheless, the cerebellar role is not restricted only to error-based learning, but it also contributes to several cognitive processes. Therefore, here, we tested if cerebellar ataxia patients are affected in two tasks, one that depends on error-based learning and the other that prevents the use of error-based learning. Our results showed that cerebellar patients have deficits in both visuomotor tasks; however, while error-based learning tasks deficits correlated with the motor impairments, the motor error-dependent task did not correlate with any motor measure.

A Performance Survey on Stack-based and Register-based Virtual Machines

OpenAIRE

Fang, Ruijie; Liu, Siqi

2016-01-01

Virtual machines have been widely adapted for high-level programming language implementations and for providing a degree of platform neutrality. As the overall use and adaptation of virtual machines grow, the overall performance of virtual machines has become a widely-discussed topic. In this paper, we present a survey on the performance differences of the two most widely adapted types of virtual machines - the stack-based virtual machine and the register-based virtual machine - using various...

GPU-based parallel algorithm for blind image restoration using midfrequency-based methods

Science.gov (United States)

Xie, Lang; Luo, Yi-han; Bao, Qi-liang

2013-08-01

GPU-based general-purpose computing is a new branch of modern parallel computing, so the study of parallel algorithms specially designed for GPU hardware architecture is of great significance. In order to solve the problem of high computational complexity and poor real-time performance in blind image restoration, the midfrequency-based algorithm for blind image restoration was analyzed and improved in this paper. Furthermore, a midfrequency-based filtering method is also used to restore the image hardly with any recursion or iteration. Combining the algorithm with data intensiveness, data parallel computing and GPU execution model of single instruction and multiple threads, a new parallel midfrequency-based algorithm for blind image restoration is proposed in this paper, which is suitable for stream computing of GPU. In this algorithm, the GPU is utilized to accelerate the estimation of class-G point spread functions and midfrequency-based filtering. Aiming at better management of the GPU threads, the threads in a grid are scheduled according to the decomposition of the filtering data in frequency domain after the optimization of data access and the communication between the host and the device. The kernel parallelism structure is determined by the decomposition of the filtering data to ensure the transmission rate to get around the memory bandwidth limitation. The results show that, with the new algorithm, the operational speed is significantly increased and the real-time performance of image restoration is effectively improved, especially for high-resolution images.

SB certification for mixture-based specification for flexible base.

Science.gov (United States)

2012-10-01

Presentation topics: : Establish List of Qualified Producers; : Producers Responsible for Process Control/Quality Control; : Reduce TxDOT Sampling and Testing; : Expedite Aggregate Base Acceptance; : Share Responsibility (Producer/TxDOT) for Quality ...

Lunar lander stage requirements based on the Civil Needs Data Base

Science.gov (United States)

Mulqueen, John A.

1992-01-01

This paper examines the lunar lander stages that will be necessary for the future exploration and development of the Moon. Lunar lander stage sizing is discussed based on the projected lunar payloads listed in the Civil Needs Data Base. Factors that will influence the lander stage design are identified and discussed. Some of these factors are (1) lunar orbiting and lunar surface lander bases; (2) implications of direct landing trajectories and landing from a parking orbit; (3) implications of landing site and parking orbit; (4) implications of landing site and parking orbit selection; (5) the use of expendable and reusable lander stages; and (6) the descent/ascent trajectories. Data relating the lunar lander stage design requirements to each of the above factors and others are presented in parametric form. These data will provide useful design data that will be applicable to future mission model modifications and design studies.

Knowledge-based utility

International Nuclear Information System (INIS)

Chwalowski, M.

1997-01-01

This presentation provides industry examples of successful marketing practices by companies facing deregulation and competition. The common thread through the examples is that long term survival of today's utility structure is dependent on the strategic role of knowledge. As opposed to regulated monopolies which usually own huge physical assets and have very little intelligence about their customers, unregulated enterprises tend to be knowledge-based, characterized by higher market value than book value. A knowledge-based enterprise gathers data, creates information and develops knowledge by leveraging it as a competitive weapon. It institutionalizes human knowledge as a corporate asset for use over and over again by the use of databases, computer networks, patents, billing, collection and customer services (BCCS), branded interfaces and management capabilities. Activities to become knowledge-based such as replacing inventory/fixed assets with information about material usage to reduce expenditure and achieve more efficient operations, and by focusing on integration and value-adding delivery capabilities, were reviewed

Value-based genomics.

Science.gov (United States)

Gong, Jun; Pan, Kathy; Fakih, Marwan; Pal, Sumanta; Salgia, Ravi

2018-03-20

Advancements in next-generation sequencing have greatly enhanced the development of biomarker-driven cancer therapies. The affordability and availability of next-generation sequencers have allowed for the commercialization of next-generation sequencing platforms that have found widespread use for clinical-decision making and research purposes. Despite the greater availability of tumor molecular profiling by next-generation sequencing at our doorsteps, the achievement of value-based care, or improving patient outcomes while reducing overall costs or risks, in the era of precision oncology remains a looming challenge. In this review, we highlight available data through a pre-established and conceptualized framework for evaluating value-based medicine to assess the cost (efficiency), clinical benefit (effectiveness), and toxicity (safety) of genomic profiling in cancer care. We also provide perspectives on future directions of next-generation sequencing from targeted panels to whole-exome or whole-genome sequencing and describe potential strategies needed to attain value-based genomics.

Gossip-Based Dissemination

Science.gov (United States)

Friedman, Roy; Kermarrec, Anne-Marie; Miranda, Hugo; Rodrigues, Luís

Gossip-based networking has emerged as a viable approach to disseminate information reliably and efficiently in large-scale systems. Initially introduced for database replication [222], the applicability of the approach extends much further now. For example, it has been applied for data aggregation [415], peer sampling [416] and publish/subscribe systems [845]. Gossip-based protocols rely on a periodic peer-wise exchange of information in wired systems. By changing the way each peer is selected for the gossip communication, and which data are exchanged and processed [451], gossip systems can be used to perform different distributed tasks, such as, among others: overlay maintenance, distributed computation, and information dissemination (a collection of papers on gossip can be found in [451]). In a wired setting, the peer sampling service, allowing for a random or specific peer selection, is often provided as an independent service, able to operate independently from other gossip-based services [416].

24 CFR 1000.103 - How may IHBG funds be used for tenant-based or project-based rental assistance?

Science.gov (United States)

2010-04-01

... Housing Activities § 1000.103 How may IHBG funds be used for tenant-based or project-based rental assistance? (a) IHBG funds may be used for project-based or tenant-based rental assistance. (b) IHBG funds may be used for project-based or tenant-based rental assistance that is provided in a manner...

Aquaporin-4 autoantibodies in neuromyelitis optica spectrum disorders: comparison between tissue-based and cell-based indirect immunofluorescence assays

Directory of Open Access Journals (Sweden)

Chan Koon H

2010-09-01

Full Text Available Abstract Background Neuromyelitis optica spectrum disorders (NMOSD are severe central nervous system inflammatory demyelinating disorders (CNS IDD characterized by monophasic or relapsing, longitudinally extensive transverse myelitis (LETM and/or optic neuritis (ON. A significant proportion of NMOSD patients are seropositive for aquaporin-4 (AQP4 autoantibodies. We compared the AQP4 autoantibody detection rates of tissue-based indirect immunofluorescence assay (IIFA and cell-based IIFA. Methods Serum of Chinese CNS IDD patients were assayed for AQP4 autoantibodies by tissue-based IIFA using monkey cerebellum and cell-based IIFA using transfected HEK293 cells which express human AQP4 on their cell membranes. Results In total, 128 CNS IDD patients were studied. We found that 78% of NMO patients were seropositive for AQP4 autoantibodies by cell-based IIFA versus 61% by tissue-based IFA (p = 0.250, 75% of patients having relapsing myelitis (RM with LETM were seropositive by cell-based IIFA versus 50% by tissue-based IIFA (p = 0.250, and 33% of relapsing ON patients were seropositive by cell-based IIFA versus 22% by tissue-based IIFA (p = 1.000; however the differences were not statistically significant. All patients seropositive by tissue-based IIFA were also seropositive for AQP4 autoantibodies by cell-based IIFA. Among 29 NMOSD patients seropositive for AQP4 autoantibodies by cell-based IIFA, 20 (69% were seropositive by tissue-based IIFA. The 9 patients seropositive by cell-based IIFA while seronegative by tissue-based IIFA had NMO (3, RM with LETM (3, a single attack of LETM (1, relapsing ON (1 and a single ON attack (1. Among 23 NMO or RM patients seropositive for AQP4 autoantibodies by cell-based IIFA, comparison between those seropositive (n = 17 and seronegative (n = 6 by tissue-based IIFA revealed no differences in clinical and neuroradiological characteristics between the two groups. Conclusion Cell-based IIFA is slightly more sensitive

Preparation of a bio-based epoxy with comparable properties to those of petroleum-based counterparts

Directory of Open Access Journals (Sweden)

X. Q. Liu

2012-04-01

Full Text Available In this paper a bio-based epoxy with outstanding thermal and mechanical properties was synthesized using a rosin-based epoxy monomer and a rosin-based curing agent. The chemical structures of rosin based epoxy monomer and curing agent were confirmed by Nuclear Magnetic Resonance (NMR and Fourier Transform Infrared (FT-IR spectra. The flexural mechanical and dynamic mechanical properties as well as thermal stability of the cured epoxy were investigated. The results showed that the cured epoxy exhibited a glass transition temperature (Tg of 164°C and its flexural strength and modulus were as high as 70 and 2200 MPa, respectively. This indicated that a wholly bio-based epoxy resin possessing high performance was successfully obtained.

Graphene-based field-effect transistor biosensors

Science.gov (United States)

Chen; , Junhong; Mao, Shun; Lu, Ganhua

2017-06-14

The disclosure provides a field-effect transistor (FET)-based biosensor and uses thereof. In particular, to FET-based biosensors using thermally reduced graphene-based sheets as a conducting channel decorated with nanoparticle-biomolecule conjugates. The present disclosure also relates to FET-based biosensors using metal nitride/graphene hybrid sheets. The disclosure provides a method for detecting a target biomolecule in a sample using the FET-based biosensor described herein.

Hydrogel based occlusion systems

NARCIS (Netherlands)

Stam, F.A.; Jackson, N.; Dubruel, P.; Adesanya, K.; Embrechts, A.; Mendes, E.; Neves, H.P.; Herijgers, P.; Verbrugghe, Y.; Shacham, Y.; Engel, L.; Krylov, V.

2013-01-01

A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a

Defining Nature-Based Preschools

Science.gov (United States)

Larimore, Rachel

2016-01-01

Nature-based early childhood education. Nature-based preschool. Nature preschool. Forest kindergarten. Nature kindergarten. Waldkindergarten. Forest school. These are a few of the program terms currently being discussed among early childhood environmental education professionals in the United States. Why is there so much discussion about the names…

An Evidence-Based Framework for Evidence-Based Management in ...

African Journals Online (AJOL)

2018-05-01

May 1, 2018 ... BACKGROUND: Evidence-based management (EBMgt) is a growing literature concept in ... principles are developing across disciplines such as education, criminology ..... Australian Health Review. 2012;36(3):284-90. 17.

Finite Elements on Point Based Surfaces

NARCIS (Netherlands)

Clarenz, U.; Rumpf, M.; Telea, A.

2004-01-01

We present a framework for processing point-based surfaces via partial differential equations (PDEs). Our framework efficiently and effectively brings well-known PDE-based processing techniques to the field of point-based surfaces. Our method is based on the construction of local tangent planes and

47 CFR 65.800 - Rate base.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Rate base. 65.800 Section 65.800 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERSTATE RATE OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Rate Base § 65.800 Rate base. The rate base shall...

Summary of TMI-2 data bases

International Nuclear Information System (INIS)

Brower, R.W.

1987-09-01

This report summarizes seven major data base products produced by the Data Reduction and qualification Section of the TMI-2 Accident Evaluation Program. The purpose and a brief description of data base structure are presented in the introductory section, together with rational involved in selection of data base media. Major emphasis in the report is placed in more detailed examinations of four personal computer data bases which utilize an INEL developed data base management system, SAGE. Content of each data base is described, the current development status is defined and future activity associated with each dynamic structures is outlined

Video-based rendering

CERN Document Server

Magnor, Marcus A

2005-01-01

Driven by consumer-market applications that enjoy steadily increasing economic importance, graphics hardware and rendering algorithms are a central focus of computer graphics research. Video-based rendering is an approach that aims to overcome the current bottleneck in the time-consuming modeling process and has applications in areas such as computer games, special effects, and interactive TV. This book offers an in-depth introduction to video-based rendering, a rapidly developing new interdisciplinary topic employing techniques from computer graphics, computer vision, and telecommunication en

Different perspectives on economic base.

Science.gov (United States)

Lisa K. Crone; Richard W. Haynes; Nicholas E. Reyna

1999-01-01

Two general approaches for measuring the economic base are discussed. Each method is used to define the economic base for each of the counties included in the Interior Columbia Basin Ecosystem Management Project area. A more detailed look at four selected counties results in similar findings from different approaches. Limitations of economic base analysis also are...

46 CFR 64.27 - Base.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Base. 64.27 Section 64.27 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MARINE PORTABLE TANKS AND CARGO HANDLING SYSTEMS Standards for an MPT § 64.27 Base. The base of an MPT must be as wide and as long as the tank. ...

Comparison of Real-Time Intraoperative Ultrasound-Based Dosimetry With Postoperative Computed Tomography-Based Dosimetry for Prostate Brachytherapy

International Nuclear Information System (INIS)

Nag, Subir; Shi Peipei; Liu Bingren; Gupta, Nilendu; Bahnson, Robert R.; Wang, Jian Z.

2008-01-01

Purpose: To evaluate whether real-time intraoperative ultrasound (US)-based dosimetry can replace conventional postoperative computed tomography (CT)-based dosimetry in prostate brachytherapy. Methods and Materials: Between December 2001 and November 2002, 82 patients underwent 103 Pd prostate brachytherapy. An interplant treatment planning system was used for real-time intraoperative transrectal US-guided treatment planning. The dose distribution was updated according to the estimated seed position to obtain the dose-volume histograms. Postoperative CT-based dosimetry was performed a few hours later using the Theraplan-Plus treatment planning system. The dosimetric parameters obtained from the two imaging modalities were compared. Results: The results of this study revealed correlations between the US- and CT-based dosimetry. However, large variations were found in the implant-quality parameters of the two modalities, including the doses covering 100%, 90%, and 80% of the prostate volume and prostate volumes covered by 100%, 150%, and 200% of the prescription dose. The mean relative difference was 38% and 16% for doses covering 100% and 90% of the prostate volume and 10% and 21% for prostate volumes covered by 100% and 150% of the prescription dose, respectively. The CT-based volume covered by 200% of the prescription dose was about 30% greater than the US-based one. Compared with CT-based dosimetry, US-based dosimetry significantly underestimated the dose to normal organs, especially for the rectum. The average US-based maximal dose and volume covered by 100% of the prescription dose for the rectum was 72 Gy and 0.01 cm 3 , respectively, much lower than the 159 Gy and 0.65 cm 3 obtained using CT-based dosimetry. Conclusion: Although dosimetry using intraoperative US-based planning provides preliminary real-time information, it does not accurately reflect the postoperative CT-based dosimetry. Until studies have determined whether US-based dosimetry or

Value-based medicine: concepts and application

OpenAIRE

Jong-Myon Bae

2015-01-01

Global healthcare in the 21st century is characterized by evidence-based medicine (EBM), patient-centered care, and cost effectiveness. EBM involves clinical decisions being made by integrating patient preference with medical treatment evidence and physician experiences. The Center for Value-Based Medicine suggested value-based medicine (VBM) as the practice of medicine based upon the patient-perceived value conferred by an intervention. VBM starts with the best evidence-based data and conver...

The comparative effectiveness of a team-based versus group-based physical activity intervention for cancer survivors.

Science.gov (United States)

Carter, Cindy L; Onicescu, Georgiana; Cartmell, Kathleen B; Sterba, Katherine R; Tomsic, James; Alberg, Anthony J

2012-08-01

Physical activity benefits cancer survivors, but the comparative effectiveness of a team-based delivery approach remains unexplored. The hypothesis tested was that a team-based physical activity intervention delivery approach has added physical and psychological benefits compared to a group-based approach. A team-based sport accessible to survivors is dragon boating, which requires no previous experience and allows for diverse skill levels. In a non-randomized trial, cancer survivors chose between two similarly structured 8-week programs, a dragon boat paddling team (n = 68) or group-based walking program (n = 52). Three separate intervention rounds were carried out in 2007-2008. Pre-post testing measured physical and psychosocial outcomes. Compared to walkers, paddlers had significantly greater (all p team cohesion, program adherence/attendance, and increased upper-body strength. For quality-of-life outcomes, both interventions were associated with pre-post improvements, but with no clear-cut pattern of between-intervention differences. These hypothesis-generating findings suggest that a short-term, team-based physical activity program (dragon boat paddling) was associated with increased cohesion and adherence/attendance. Improvements in physical fitness and psychosocial benefits were comparable to a traditional, group-based walking program. Compared to a group-based intervention delivery format, the team-based intervention delivery format holds promise for promoting physical activity program adherence/attendance in cancer survivors.

Self-guided internet-based and mobile-based stress management for employees

DEFF Research Database (Denmark)

Ebert, D. D.; Heber, E.; Berking, M.

2016-01-01

Objective This randomised controlled trial (RCT) aimed to evaluate the efficacy of a self-guided internet-based stress management intervention (iSMI) for employees compared to a 6-month wait-list control group (WLC) with full access for both groups to treatment as usual. M e t h o d A sample of 264...... of stressed employees. Internet-based self-guided interventions could be an acceptable, effective and potentially costeffective approach to reduce the negative consequences associated with work-related stress....

Replacing fossil based plastic performance products by bio-based plastic products-Technical feasibility

NARCIS (Netherlands)

Oever, van den Martien; Molenveld, Karin

2017-01-01

Larger scale market introduction of new bio-based products requires a clear advantage regarding sustainability, as well as an adequate techno-economic positioning relative to fossil based products. In a previous paper [Broeren et al., 2016], LCA results per kg and per functionality equivalent of

Benchmarking gate-based quantum computers

Science.gov (United States)

Michielsen, Kristel; Nocon, Madita; Willsch, Dennis; Jin, Fengping; Lippert, Thomas; De Raedt, Hans

2017-11-01

With the advent of public access to small gate-based quantum processors, it becomes necessary to develop a benchmarking methodology such that independent researchers can validate the operation of these processors. We explore the usefulness of a number of simple quantum circuits as benchmarks for gate-based quantum computing devices and show that circuits performing identity operations are very simple, scalable and sensitive to gate errors and are therefore very well suited for this task. We illustrate the procedure by presenting benchmark results for the IBM Quantum Experience, a cloud-based platform for gate-based quantum computing.

Model-based internal wave processing

Energy Technology Data Exchange (ETDEWEB)

Candy, J.V.; Chambers, D.H.

1995-06-09

A model-based approach is proposed to solve the oceanic internal wave signal processing problem that is based on state-space representations of the normal-mode vertical velocity and plane wave horizontal velocity propagation models. It is shown that these representations can be utilized to spatially propagate the modal (dept) vertical velocity functions given the basic parameters (wave numbers, Brunt-Vaisala frequency profile etc.) developed from the solution of the associated boundary value problem as well as the horizontal velocity components. Based on this framework, investigations are made of model-based solutions to the signal enhancement problem for internal waves.

Semantics-based Automated Web Testing

Directory of Open Access Journals (Sweden)

Hai-Feng Guo

2015-08-01

Full Text Available We present TAO, a software testing tool performing automated test and oracle generation based on a semantic approach. TAO entangles grammar-based test generation with automated semantics evaluation using a denotational semantics framework. We show how TAO can be incorporated with the Selenium automation tool for automated web testing, and how TAO can be further extended to support automated delta debugging, where a failing web test script can be systematically reduced based on grammar-directed strategies. A real-life parking website is adopted throughout the paper to demonstrate the effectivity of our semantics-based web testing approach.

Enhancing the LVRT Capability of PMSG-Based Wind Turbines Based on R-SFCL

Science.gov (United States)

Xu, Lin; Lin, Ruixing; Ding, Lijie; Huang, Chunjun

2018-03-01

A novel low voltage ride-through (LVRT) scheme for PMSG-based wind turbines based on the Resistor Superconducting Fault Current Limiter (R-SFCL) is proposed in this paper. The LVRT scheme is mainly formed by R-SFCL in series between the transformer and the Grid Side Converter (GSC), and basic modelling has been discussed in detail. The proposed LVRT scheme is implemented to interact with PMSG model in PSCAD/EMTDC under three phase short circuit fault condition, which proves that the proposed scheme based on R-SFCL can improve the transient performance and LVRT capability to consolidate grid connection with wind turbines.

Professionalism and evidence-based practice

DEFF Research Database (Denmark)

Rasmussen, Palle

2015-01-01

of evidence- based methods in Danish pre-school education and care. The management sees the use of these methods as strengthening pre- school teacher professionalism, but the actual practices in the day-careinstitutions are ambiguous. In some cases, using the methods becomes an end in itself and tends......The idea of evidence- based practice is influential in public welfare services, including education. The idea is controversial, however, not least because it involves a poten tial redefinition of the relation ship between knowledge, authority and professionalism. This is discussed based on a study...... to displace important educational objectives. In other cases, the methods are reflectively adjusted to a given context. Used in this way only, evid ence-based practice and methodology is a valuable resource for professional practice in education. From such a perspective, at least some types of research based...