WorldWideScience

Sample records for base line study

  1. Base-line studies for DAE establishments

    International Nuclear Information System (INIS)

    Puranik, V.D.

    2012-01-01

    The Department of Atomic Energy has establishments located in various regions of the country and they include front-end fuel cycle facilities, nuclear power stations, back-end fuel cycle facilities and facilities for research and societal applications. These facilities handle naturally occurring radionuclides such as uranium, thorium and a variety of man-made radionuclides. These radionuclides are handled with utmost care so that they do not affect adversely the occupational workers or the members of public residing nearby. There is safety culture of the highest standard existing in all DAE establishments and it matches with the international standards. In addition, there is a perpetual environmental monitoring program carried out by the Environmental Survey Laboratories (ESLs) located at all DAE establishments. The environmental data generated by such program is studied regularly by experts to ensure compliance with the regulatory requirements. The regulatory requirements in the country are of international standards and ensure adequate protection of workers and members of public. In addition to such continued monitoring program and studies being carried out for the ongoing projects, base-line studies are carried out for all the new projects of the DAE. The purpose of the base-line studies is to establish a detailed base-line data set for a new DAE location well before the foundation stone is laid, so that the data collected when there is no departmental activity can be compared with the data generated later by the ESL. The data so generated is site specific and it varies from place to place depending upon the location of the site, e.g., inland or coastal, the presence of water bodies and pattern of irrigation, the geological characteristics of the location, the local culture and habits of the people, population density and urban or rural background. The data to be recorded as base-line data is generated over a period of at least one year covering all the seasons

  2. Geochemical approach values to the base line (Cu, Cr, Pb, Zn and P) for environmental studies in Montevideo coastal zone

    International Nuclear Information System (INIS)

    Brugnoli, E.; Burone, L.; Hutton, M.; Tuduri, A.; Bueno, C.; Muniz, P.; Venturini, N.; Garcia-Rodriguez, F.

    2012-01-01

    The geochemical base line values (background) represent the natural chemical concentrations (heavy metals) in sediments and soils. These are used in archaeological surveys to identify anomalies, and environmental studies of contaminated areas. In Montevideo coastal zone are explored the base line values for geochemical application and enrichment index

  3. Experimental study on distributed optical fiber-based approach monitoring saturation line in levee engineering

    Science.gov (United States)

    Su, Huaizhi; Li, Hao; Kang, Yeyuan; Wen, Zhiping

    2018-02-01

    Seepage is one of key factors which affect the levee engineering safety. The seepage danger without timely detection and rapid response may likely lead to severe accidents such as seepage failure, slope instability, and even levee break. More than 90 percent of levee break events are caused by the seepage. It is very important for seepage behavior identification to determine accurately saturation line in levee engineering. Furthermore, the location of saturation line has a major impact on slope stability in levee engineering. Considering the structure characteristics and service condition of levee engineering, the distributed optical fiber sensing technology is introduced to implement the real-time observation of saturation line in levee engineering. The distributed optical fiber temperature sensor system (DTS)-based monitoring principle of saturation line in levee engineering is investigated. An experimental platform, which consists of DTS, heating system, water-supply system, auxiliary analysis system and levee model, is designed and constructed. The monitoring experiment of saturation line in levee model is implemented on this platform. According to the experimental results, the numerical relationship between moisture content and thermal conductivity in porous medium is identified. A line heat source-based distributed optical fiber method obtaining the thermal conductivity in porous medium is developed. A DTS-based approach is proposed to monitor the saturation line in levee engineering. The embedment pattern of optical fiber for monitoring saturation line is presented.

  4. Feasibility Study for Installing Machine in Production Line to Avoid Particle Contamination Based on CFD Simulation

    Science.gov (United States)

    Khaokom, Adisorn; Thongsri, Jatuporn

    2017-10-01

    Ventilation system inside production line for electronic component production needs to meet the factory standard. Because it can eliminate small particles which may cause of human or machine in production as well as it can distribute the circulating air temperature uniformly. CFD is used in this research in order to study the feasibility and plan for machine layout in production line before actual installation. The simulation shows the airflow in every area inside production line. From simulation with releasing the particles from human and machine is found that this ventilation system generates airflow that makes most particles float out of the machines and no particle downs to the conveyor, it results to contamination. In addition, the simulation also shows the range of 19-26 °C air temperature that meets the factory standard. The results of this research are the parts of the data to renovate the production line to get more efficiency and proper on the production.

  5. Study on blast furnace cooling stave for various refractory linings based on numerical modeling

    International Nuclear Information System (INIS)

    Mohanty, T R; Sahoo, S K; Moharana, M K

    2016-01-01

    Cooling technology for refractory lining of blast furnace is very important for the metallurgical industry, because it can substantially increase output and operation life of furnaces. A three dimensional mathematical model for the temperature field of the blast furnace stave cooler with refractory lining has been developed and analyzed. The temperature and heat dissipated by stave cooler is examined by using the finite element method. The cast steel stave is studied and computational analysis is made to know the effect of the cooling water velocity, temperature, and the lining material on the maximum temperature of the stave hot surface. The refractory lining materials, which are used in this experiment, are high alumina bricks with different stave materials (copper, aluminum and cast iron). The obtained numerical calculations are compared with that obtained from experiments performed at Rourkela Steel Plant, Odisha taking a stave in belly zone having maximum heat load shows very good agreement. (paper)

  6. Base Flood Elevation (BFE) Lines

    Data.gov (United States)

    Department of Homeland Security — The Base Flood Elevation (BFE) table is required for any digital data where BFE lines will be shown on the corresponding Flood Insurance Rate Map (FIRM). Normally if...

  7. A Case Study of Line-of-Balance based Schedule Planning and Control System

    OpenAIRE

    Seppänen, Olli; Aalto, Erno

    2005-01-01

    Line-of-Balance is a graphical technique which can be used to plan and manage work flow. It is suit-able for construction projects because of their large degree of repetition. Despite its strengths Line-of-Balance has not gained widespread use in construction industry internationally. However, it has been used as the principal scheduling tool in Finland since 1980s. As a result of two decades of research and use in industry, a comprehensive schedule planning and control system has been develo...

  8. Study on Scattered Data Points Interpolation Method Based on Multi-line Structured Light

    International Nuclear Information System (INIS)

    Fan, J Y; Wang, F G; W, Y; Zhang, Y L

    2006-01-01

    Aiming at the range image obtained through multi-line structured light, a regional interpolation method is put forward in this paper. This method divides interpolation into two parts according to the memory format of the scattered data, one is interpolation of the data on the stripes, and the other is interpolation of data between the stripes. Trend interpolation method is applied to the data on the stripes, and Gauss wavelet interpolation method is applied to the data between the stripes. Experiments prove regional interpolation method feasible and practical, and it also promotes the speed and precision

  9. Experimental study of a DMD based compressive line sensing imaging system in the turbulence environment

    Science.gov (United States)

    Ouyang, Bing; Hou, Weilin; Gong, Cuiling; Caimi, Frank M.; Dalgleish, Fraser R.; Vuorenkoski, Anni K.

    2016-05-01

    The Compressive Line Sensing (CLS) active imaging system has been demonstrated to be effective in scattering mediums, such as turbid coastal water through simulations and test tank experiments. Since turbulence is encountered in many atmospheric and underwater surveillance applications, a new CLS imaging prototype was developed to investigate the effectiveness of the CLS concept in a turbulence environment. Compared with earlier optical bench top prototype, the new system is significantly more robust and compact. A series of experiments were conducted at the Naval Research Lab's optical turbulence test facility with the imaging path subjected to various turbulence intensities. In addition to validating the system design, we obtained some unexpected exciting results - in the strong turbulence environment, the time-averaged measurements using the new CLS imaging prototype improved both SNR and resolution of the reconstructed images. We will discuss the implications of the new findings, the challenges of acquiring data through strong turbulence environment, and future enhancements.

  10. Base line study on demographic and health pattern around uranium mining area at Tummalapalle

    International Nuclear Information System (INIS)

    Tondare, Devidas; Bala Krishna, C.; Ganesh, B.; Vinod Kumar, A.

    2013-01-01

    Aim of the study is to document baseline data on the socio-economic, demographic and health status of the study area with specific objective to generate household information on infrastructure, housing, agriculture, drinking water and sanitation facilities

  11. A New Approach to Line Simplification Based on Image Processing: A Case Study of Water Area Boundaries

    Directory of Open Access Journals (Sweden)

    Yilang Shen

    2018-01-01

    Full Text Available Line simplification is an important component of map generalization. In recent years, algorithms for line simplification have been widely researched, and most of them are based on vector data. However, with the increasing development of computer vision, analysing and processing information from unstructured image data is both meaningful and challenging. Therefore, in this paper, we present a new line simplification approach based on image processing (BIP, which is specifically designed for raster data. First, the key corner points on a multi-scale image feature are detected and treated as candidate points. Then, to capture the essence of the shape within a given boundary using the fewest possible segments, the minimum-perimeter polygon (MPP is calculated and the points of the MPP are defined as the approximate feature points. Finally, the points after simplification are selected from the candidate points by comparing the distances between the candidate points and the approximate feature points. An empirical example was used to test the applicability of the proposed method. The results showed that (1 when the key corner points are detected based on a multi-scale image feature, the local features of the line can be extracted and retained and the positional accuracy of the proposed method can be maintained well; and (2 by defining the visibility constraint of geographical features, this method is especially suitable for simplifying water areas as it is aligned with people’s visual habits.

  12. Study on the Application of the Tie-Line-Table-Look-Up-Based Methods to Flash Calculations in Compositional Simulations

    DEFF Research Database (Denmark)

    Yan, Wei; Belkadi, Abdelkrim; Michelsen, Michael Locht

    2013-01-01

    Flash calculation can be a time-consuming part in compositional reservoir simulations, and several approaches have been proposed to speed it up. One recent approach is the shadow-region method that reduces the computation time mainly by skipping stability analysis for a large portion...... of the compositions in the single-phase region. In the two-phase region, a highly efficient Newton-Raphson algorithm can be used with the initial estimates from the previous step. Another approach is the compositional-space adaptive-tabulation (CSAT) approach, which is based on tie-line table look-up (TTL). It saves...... be made. Comparison between the shadow-region approach and the approximation approach, including TTL and TDBA, has been made with a slimtube simulator by which the simulation temperature and the simulation pressure are set constant. It is shown that TDBA can significantly improve the speed in the two...

  13. Strapdown Airborne Gravimetry Quality Assessment Method Based on Single Survey Line Data: A Study by SGA-WZ02 Gravimeter

    Science.gov (United States)

    Wu, Meiping; Cao, Juliang; Zhang, Kaidong; Cai, Shaokun; Yu, Ruihang

    2018-01-01

    Quality assessment is an important part in the strapdown airborne gravimetry. Root mean square error (RMSE) evaluation method is a classical way to evaluate the gravimetry quality, but classical evaluation methods are preconditioned by extra flight or reference data. Thus, a method, which is able to largely conquer the premises of classical quality assessment methods and can be used in single survey line, has been developed in this paper. According to theoretical analysis, the method chooses the stability of two horizontal attitude angles, horizontal specific force and vertical specific force as the determinants of quality assessment method. The actual data, collected by SGA-WZ02 from 13 flights 21 lines in certain survey, was used to build the model and elaborate the method. To substantiate the performance of the quality assessment model, the model is applied in extra repeat line flights from two surveys. Compared with internal RMSE, standard deviation of assessment residuals are 0.23 mGal and 0.16 mGal in two surveys, which shows that the quality assessment method is reliable and stricter. The extra flights are not necessary by specially arranging the route of flights. The method, summarized from SGA-WZ02, is a feasible approach to assess gravimetry quality using single line data and is also suitable for other strapdown gravimeters. PMID:29373535

  14. Are risk estimates biased in follow-up studies of psychosocial factors with low base-line participation?

    Directory of Open Access Journals (Sweden)

    Andersen Johan

    2011-07-01

    Full Text Available Abstract Background Low participation in population-based follow-up studies addressing psychosocial risk factors may cause biased estimation of health risk but the issue has seldom been examined. We compared risk estimates for selected health outcomes among respondents and the entire source population. Methods In a Danish cohort study of associations between psychosocial characteristics of the work environment and mental health, the source population of public service workers comprised 10,036 employees in 502 work units of which 4,489 participated (participation rate 45%. Data on the psychosocial work environment were obtained for each work unit by calculating the average of the employee self-reports. The average values were assigned all employees and non-respondent at the work unit. Outcome data on sick leave and prescription of antidepressant medication during the follow-up period (1.4.2007-31.12.2008 was obtained by linkage to national registries. Results Respondents differed at baseline from non-respondents by gender, age, employment status, sick leave and hospitalization for affective disorders. However, risk estimates for sick leave and prescription of antidepressant medication, during follow-up, based on the subset of participants, did only differ marginally from risk estimates based upon the entire population. Conclusions We found no indications that low participation at baseline distorts the estimates of associations between the work unit level of psychosocial work environment and mental health outcomes during follow-up. These results may not be valid for other exposures or outcomes.

  15. Microculture-based chemosensitivity testing: a feasibility study comparing freshly explanted human melanoma cells with human melanoma cell lines.

    Science.gov (United States)

    Marshall, E S; Finlay, G J; Matthews, J H; Shaw, J H; Nixon, J; Baguley, B C

    1992-03-04

    The culture of cancer cells has many applications in chemosensitivity testing and new drug development. Our goal was to adapt simple semiautomated microculture methods for testing the chemosensitivity of melanoma cells freshly recovered from patients' tumors. Cells were cultured on a substrate of agarose and exposed continuously to cytotoxic drugs, the effects of which were measured by determining the uptake of [3H]thymidine 4-7 days later. Immunocytochemical staining of cells cultured with 5-bromo-2'-deoxyuridine demonstrated that tumor cells were responsible for the measured thymidine incorporation. The effects of cytotoxic drugs were calculated as logarithmic 50% inhibitory concentrations and expressed as divergences from the mean in a log-mean graph. The inhibitory effects of amsacrine, etoposide, doxorubicin, cisplatin, mitomycin C, and fluorouracil were tested. Tumors differed widely in their sensitivity to these drugs, although sensitivity to the three topoisomerase-II-directed agents was highly correlated. Cells from two non-neoplastic hematopoietic progenitor cell lines (FT and 32D) showed chemosensitivity patterns distinct from those in the melanoma cells, indicating tissue selectivity. Two established melanoma cell lines, MM-96 and FME, were tested under the same conditions and showed sensitivity typical of at least some fresh specimens. These results support the validity of melanoma cell lines as models of freshly resected melanoma cells. If successfully applied to other tumor types, such semiautomated approaches could find wide application in routine hospital laboratories for the chemosensitivity testing of patients' tumor cells.

  16. Monte Carlo application based on GEANT4 toolkit to simulate a laser–plasma electron beam line for radiobiological studies

    Energy Technology Data Exchange (ETDEWEB)

    Lamia, D., E-mail: debora.lamia@ibfm.cnr.it [Institute of Molecular Bioimaging and Physiology IBFM CNR – LATO, Cefalù (Italy); Russo, G., E-mail: giorgio.russo@ibfm.cnr.it [Institute of Molecular Bioimaging and Physiology IBFM CNR – LATO, Cefalù (Italy); Casarino, C.; Gagliano, L.; Candiano, G.C. [Institute of Molecular Bioimaging and Physiology IBFM CNR – LATO, Cefalù (Italy); Labate, L. [Intense Laser Irradiation Laboratory (ILIL) – National Institute of Optics INO CNR, Pisa (Italy); National Institute for Nuclear Physics INFN, Pisa Section and Frascati National Laboratories LNF (Italy); Baffigi, F.; Fulgentini, L.; Giulietti, A.; Koester, P.; Palla, D. [Intense Laser Irradiation Laboratory (ILIL) – National Institute of Optics INO CNR, Pisa (Italy); Gizzi, L.A. [Intense Laser Irradiation Laboratory (ILIL) – National Institute of Optics INO CNR, Pisa (Italy); National Institute for Nuclear Physics INFN, Pisa Section and Frascati National Laboratories LNF (Italy); Gilardi, M.C. [Institute of Molecular Bioimaging and Physiology IBFM CNR, Segrate (Italy); University of Milano-Bicocca, Milano (Italy)

    2015-06-21

    We report on the development of a Monte Carlo application, based on the GEANT4 toolkit, for the characterization and optimization of electron beams for clinical applications produced by a laser-driven plasma source. The GEANT4 application is conceived so as to represent in the most general way the physical and geometrical features of a typical laser-driven accelerator. It is designed to provide standard dosimetric figures such as percentage dose depth curves, two-dimensional dose distributions and 3D dose profiles at different positions both inside and outside the interaction chamber. The application was validated by comparing its predictions to experimental measurements carried out on a real laser-driven accelerator. The work is aimed at optimizing the source, by using this novel application, for radiobiological studies and, in perspective, for medical applications. - Highlights: • Development of a Monte Carlo application based on GEANT4 toolkit. • Experimental measurements carried out with a laser-driven acceleration system. • Validation of Geant4 application comparing experimental data with the simulated ones. • Dosimetric characterization of the acceleration system.

  17. Arduino Based RFID Line Switching Using SSR

    Directory of Open Access Journals (Sweden)

    Michael E.

    2017-10-01

    Full Text Available The importance of line switching cannot be overemphasized as they are used to connect and disconnect substations to and from a distribution grid. At the cradle of technology line switching was achieved via the use of manual switches or fuses which could endanger life as a result of electrocution when expose during maintenance. This ill prompted the development of automated line switching using relays and contactors. With time this tends to fail as a result of wearing of the contact which is as a result of arcing and low voltage. To avert all these ills this paper presents Arduino based Radio Frequency Identification RFID line switching using Solid State Relay SSR. This is to ensure the safety of operators or technologist and to also avert the problem associated with relays and contactors using SSR. This was achieved using RFID RC-522 reader ardriuno Uno SSR and other discrete components. The system was tested and worked perfectly reducing the risk of electrocution and eliminating damage wearing of the contacts common with contactors and relays.

  18. Hockey lines for simulation-based learning.

    Science.gov (United States)

    Topps, David; Ellaway, Rachel; Kupsh, Christine

    2015-06-01

    Simulation-based health professional education is often limited in accommodating large numbers of students. Most organisations do not have enough simulation suites or staff to support growing demands. We needed to find ways to make simulation sessions more accommodating for larger groups of learners, so that more than a few individuals could be active in a simulation scenario at any one time. Moreover, we needed to make the experience meaningful for all participating learners. We used the metaphor of (ice) hockey lines and substitution 'on the fly' to effectively double the numbers of learners that can be actively engaged at once. Team players must communicate clearly, and observe keenly, so that currently playing members understand what is happening from moment to moment and incoming substitutes can take over their roles seamlessly. Most organisations do not have enough simulation suites or staff to support growing demands We found that this hockey lines approach to simulation-based team scenarios will raise learners' levels of engagement, reinforce good crew resource management (CRM) practices, enhance closed-loop communication, and help learners to understand their cognitive biases and limitations when working in high-pressure situations. During our continuing refinement of the hockey-lines approach, we developed a number of variations on the basic activity model, with various benefits and applications. Both students and teachers have been enthusiastically positive about this approach when it was introduced at our various courses and participating institutions. © 2015 John Wiley & Sons Ltd.

  19. Maintenance treatment of Uracil and Tegafur (UFT) in responders following first-line fluorouracil-based chemotherapy in metastatic gastric cancer: a randomized phase II study.

    Science.gov (United States)

    Li, Wenhua; Zhao, Xiaoying; Wang, Huijie; Liu, Xin; Zhao, Xinmin; Huang, Mingzhu; Qiu, Lixin; Zhang, Wen; Chen, Zhiyu; Guo, Weijian; Li, Jin; Zhu, Xiaodong

    2017-06-06

    Maintenance therapy proves to be effective in advanced lung and breast cancer after initial chemotherapy. The purpose of this phase II study was to evaluate the efficacy and safety of Uracil and Tegafur (UFT) maintenance in metastatic gastric cancer patients following the first-line fluorouracil-based chemotherapy. Metastatic gastric cancer patients with stable disease or a better response after the completion of first-line chemotherapy were randomized to oral UFT (360mg/m2 × 2 weeks) every 3 weeks until disease progression/intolerable toxicity or to observation (OBS). The primary endpoint was progression-free survival (PFS); the secondary endpoints were overall survival (OS) and safety. The trial was closed after the interim analysis of the 58 enrolled (120 planned) patients. Median PFS was not improved in the UFT group compared with the OBS group (3.2 months versus 3.6 months, P = 0.752), as well as the median OS (14.2 months for both, P = 0.983). However, subgroup analysis showed that low baseline hemoglobin (maintenance therapy (P = 0.032), while the normal hemoglobin patients benefit from the UFT treatment (P = 0.008). Grade 3 to 4 toxicities in the UFT group were anemia (3.4%), thrombocytopenia (3.4%) and diarrhea (6.9%). This trial did not show superiority of UFT maintenance in non-selected patients responding to fluorouracil-based first-line chemotherapy. The normal hemoglobin level at baseline is a predictive biomarker for favorable patient subsets from the maintenance treatment.

  20. Improving the performance of a filling line based on simulation

    Science.gov (United States)

    Jasiulewicz-Kaczmarek, M.; Bartkowiak, T.

    2016-08-01

    The paper describes the method of improving performance of a filling line based on simulation. This study concerns a production line that is located in a manufacturing centre of a FMCG company. A discrete event simulation model was built using data provided by maintenance data acquisition system. Two types of failures were identified in the system and were approximated using continuous statistical distributions. The model was validated taking into consideration line performance measures. A brief Pareto analysis of line failures was conducted to identify potential areas of improvement. Two improvements scenarios were proposed and tested via simulation. The outcome of the simulations were the bases of financial analysis. NPV and ROI values were calculated taking into account depreciation, profits, losses, current CIT rate and inflation. A validated simulation model can be a useful tool in maintenance decision-making process.

  1. A novel line segment detection algorithm based on graph search

    Science.gov (United States)

    Zhao, Hong-dan; Liu, Guo-ying; Song, Xu

    2018-02-01

    To overcome the problem of extracting line segment from an image, a method of line segment detection was proposed based on the graph search algorithm. After obtaining the edge detection result of the image, the candidate straight line segments are obtained in four directions. For the candidate straight line segments, their adjacency relationships are depicted by a graph model, based on which the depth-first search algorithm is employed to determine how many adjacent line segments need to be merged. Finally we use the least squares method to fit the detected straight lines. The comparative experimental results verify that the proposed algorithm has achieved better results than the line segment detector (LSD).

  2. MEMS-based transmission lines for microwave applications

    Science.gov (United States)

    Wu, Qun; Fu, Jiahui; Gu, Xuemai; Shi, Huajuan; Lee, Jongchul

    2003-04-01

    This paper mainly presents a briefly review for recent progress in MEMS-based transmission lines for use in microwave and millimeterwave range. MEMS-based transmission lines including different transmission line structure such as membrane-supported microstrip line microstrip line, coplanar microshield transmission line, LIGA micromachined planar transmission line, micromachined waveguides and coplanar waveguide are discussed. MEMS-based transmission lines are characterized by low propagation loss, wide operation frequency band, low dispersion and high quality factor, in addition, the fabrication is compatible with traditional processing of integrated circuits (IC"s). The emergence of MEMS-based transmission lines provided a solution for miniaturizing microwave system and monolithic microwave integrated circuits.

  3. Composite Based EHV AC Overhead Transmission Lines

    DEFF Research Database (Denmark)

    Sørensen, Thomas Kjærsgaard

    and analysed with regard to the possibilities, limitations and risks widespread application of composite materials on EHV AC overhead transmission lines may present. To form the basis for evaluation of the useability of composite materials, dierent overhead line projects aimed at reducing the environmental...

  4. On-Line Voltage Stability Assessment based on PMU Measurements

    DEFF Research Database (Denmark)

    Garcia-Valle, Rodrigo; P. Da Silva, Luiz C.; Nielsen, Arne Hejde

    2009-01-01

    This paper presents a method for on-line monitoring of risk voltage collapse based on synchronised phasor measurement. As there is no room for intensive computation and analysis in real-time, the method is based on the combination of off-line computation and on-line monitoring, which are correlat...

  5. Calibration Base Lines for Electronic Distance Measuring Instruments (EDMI)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A calibration base line (CBL) is a precisely measured, straight-line course of approximately 1,400 m used to calibrate Electronic Distance Measuring Instruments...

  6. Overhead distribution line models for harmonics studies

    Energy Technology Data Exchange (ETDEWEB)

    Nagpal, M.; Xu, W.; Dommel, H.W.

    1994-01-01

    Carson's formulae and Maxwell's potential coefficients are used for calculating the per unit length series impedances and shunt capacitances of the overhead lines. The per unit length values are then used for building the models, nominal pi-circuit, and equivalent pi-circuit at the harmonic frequencies. This paper studies the accuracy of these models for presenting the overhead distribution lines in steady-state harmonic solutions at frequencies up to 5 kHz. The models are verified with a field test on a 25 kV distribution line and the sensitivity of the models to ground resistivity, skin effect, and multiple grounding is reported.

  7. Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

    Directory of Open Access Journals (Sweden)

    Miguel G. Toscano

    2017-09-01

    Full Text Available Replication-defective (RD recombinant simian virus 40 (SV40-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vectors has been hampered by the lack of a packaging cell line that produces replication-competent (RC free SV40 particles in the vector production process. To solve this problem, we have adapted the current SV40 vector genome used for the production of vector particles and generated a novel Vero-based packaging cell line named SuperVero that exclusively expresses the SV40 large T antigen. SuperVero cells produce similar numbers of SV40 vector particles compared to the currently used packaging cell lines, albeit in the absence of contaminating RC SV40 particles. Our unique SV40 vector platform named SVac paves the way to clinically test a whole new generation of SV40-based therapeutics for a broad range of important diseases.

  8. Adherence to PI-based 2nd-line regimens in Cambodia is not simply a question of individual behaviour: the ANRS 12276 2PICAM study.

    Science.gov (United States)

    Sagaon-Teyssier, Luis; Mmadi Mrenda, Bakridine; Khol, Vohith; Ferradini, Laurent; Mam, Sovatha; Ngin, Sopheak; Mora, Marion; Maradan, Gwenaëlle; Vun Mean, Chhi; Ségéral, Olivier; Nerrienet, Eric; Saphonn, Vonthanak; Spire, Bruno

    2017-11-01

    To investigate whether adherence to antiretroviral treatment (ART) can be explained not only by individual factors but also by health care facilities' characteristics, among a sample of people living with HIV (PLWH) treated with PI-based regimens in Cambodia. The ANRS 12276 2PICAM cross-sectional survey was conducted between February 2013 and April 2014 among PLWH followed up in 13 health care facilities. The 1316 patients in this analysis corresponded to 90% of the total number of adult patients treated with 2nd-line PI-based regimens in Cambodia in the study period. A variable indicating whether patients were non-adherent (=1) or completely adherent (=0) was constructed. Health care facilities and individual characteristics were included in a two-level logistic model to investigate their influence on patients' adherence to ART. A total of 17% of participants did not adhere to ART. Patients in health care facilities outside the capital Phnom Penh were six times more likely to be non-adherent than those treated in health care facilities in the capital (OR: 6.15, 95% CI [1.47, 25.79]). Providing psychosocial care (provided by psychologist counsellors and/or full-time coaches) was found to be a structural facilitator of adherence, as the probability of non-adherence fell by 38.5% per each additional psychological worker present in health care facilities (OR: 0.62, 95% CI [0.43, 0.89]). Financial constraints were the main individual factor preventing adherence. Our results suggest that inefficiencies in health care delivery are detrimental to PLWH health and to the exceptional progress currently being made by Cambodia in response to HIV. Policy makers should focus on increasing the number of psychosocial workers, especially in areas outside the capital. © 2017 John Wiley & Sons Ltd.

  9. Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study.

    Directory of Open Access Journals (Sweden)

    Line S Tarpgaard

    Full Text Available We aim to test the hypothesis that high plasma YKL-40 is associated with short progression-free survival (PFS and overall survival (OS in patients with metastatic colorectal cancer (mCRC treated with first-line oxaliplatin and 5-flourouracil with or without cetuximab.A total of 566 patients in the NORDIC VII Study were randomized 1∶1∶1 to arm A (Nordic FLOX, arm B (Nordic FLOX + cetuximab, or arm C (Nordic FLOX + cetuximab for 16 weeks followed by cetuximab alone as maintenance therapy. Pretreatment plasma samples were available from 510 patients. Plasma YKL-40 was determined by ELISA and dichotomized according to the age-corrected 95% YKL-40 level in 3130 healthy subjects.Pretreatment plasma YKL-40 was elevated in 204 patients (40%, and median YKL-40 was higher in patients with mCRC than in healthy subjects (age adjusted, P<0.001. Patients with elevated YKL-40 had shorter PFS than patients with normal YKL-40 (7.5 vs. 8.2 months; hazard ratio (HR  = 1.27 95% confidence interval (CI 1.05-1.53 P = 0.013 and shorter OS (16.8 vs. 23.9 months; HR = 1.33, 1.04-1.69, P = 0.024. Multivariate Cox analysis demonstrated that elevated pretreatment YKL-40 was an independent biomarker of short OS (HR = 1.12, 1.01-1.25, P = 0.033. The ratio of the updated plasma YKL-40 (i.e. level after 1, 2, 8 weeks of treatment, and at end of treatment compared to the baseline level was associated with OS (HR = 1.27, 1.06-1.52, P = 0.011.Plasma YKL-40 is an independent prognostic biomarker in patients with mCRC treated with first-line oxaliplatin-based therapy alone or combined with cetuximab.

  10. LED-Based High-Voltage Lines Warning System

    Directory of Open Access Journals (Sweden)

    Eldar MUSA

    2013-04-01

    Full Text Available LED-based system, running with the current of high-voltage lines and converting the current flowing through the line into the light by using a toroid transformer, has been developed. The transformer’s primary winding is constituted by the high voltage power line. Toroidal core consists of two equal parts and the secondary windings are evenly placed on these two parts. The system is mounted on the high-voltage lines as a clamp. The secondary winding ends are connected in series by the connector on the clamp. LEDs are supplied by the voltage at the ends of secondary. Current flowing through highvoltage transmission lines is converted to voltage by the toroidal transformer and the light emitting LEDs are supplied with this voltage. The theory of the conversion of the current flowing through the line into the light is given. The system, running with the current of the line and converting the current into the light, has been developed. System has many application areas such as warning high voltage lines (warning winches to not hinder the high-voltage lines when working under the lines, warning planes to not touch the high-voltage lines, remote measurement of high-voltage line currents, and local illumination of the line area

  11. Cultivation studies of Taiwanese native Miscanthus floridulus lines

    International Nuclear Information System (INIS)

    Huang, C.L.; Liao, W.C.; Lai, Y.C.

    2011-01-01

    Four Taiwanese native Miscanthus floridulus lines, collected at altitudes of 260, 500, 1000, and 1500 m were cultivated in 2009 and 2010. The plant height and tiller numbers of four M. floridulus lines increased gradually along with the growing time. These M. floridulus lines had the tallest plant height and most tiller number after these species were planted 210 days. Line 3, which was collected at the altitude of 1000 m, had the ability to grow at low temperature. Line 3 M. floridulus had the highest plant height, tiller number, fresh and dry yields than other three lines. Fresh and dry yields of Line 3 were positively correlated to the plant height, tiller number, and leaf width, but showed no correlation with the leaf length. The correlation between agronomic traits and climatic data was also studied. Results can be used as a model for developing a non-food crop-based energy production system in the future. -- Highlights: → Miscanthus floridulus collected at 1000 m altitude had the highest plant height, tiller number, fresh and dry yields. → Fresh and dry yields of were positively correlated to the plant height, tiller number, and leaf width. → Fresh and dry yields showed no correlation with the leaf length. → The accumulative rainfall, temperature, radiation, and exposure time to radiation were positively correlated to the plant height, leaf length and leaf width.

  12. A Novel Assembly Line Balancing Method Based on PSO Algorithm

    Directory of Open Access Journals (Sweden)

    Xiaomei Hu

    2014-01-01

    Full Text Available Assembly line is widely used in manufacturing system. Assembly line balancing problem is a crucial question during design and management of assembly lines since it directly affects the productivity of the whole manufacturing system. The model of assembly line balancing problem is put forward and a general optimization method is proposed. The key data on assembly line balancing problem is confirmed, and the precedence relations diagram is described. A double objective optimization model based on takt time and smoothness index is built, and balance optimization scheme based on PSO algorithm is proposed. Through the simulation experiments of examples, the feasibility and validity of the assembly line balancing method based on PSO algorithm is proved.

  13. LINES

    Directory of Open Access Journals (Sweden)

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  14. Computer-based mechanical design of overhead lines

    Science.gov (United States)

    Rusinaru, D.; Bratu, C.; Dinu, R. C.; Manescu, L. G.

    2016-02-01

    Beside the performance, the safety level according to the actual standards is a compulsory condition for distribution grids’ operation. Some of the measures leading to improvement of the overhead lines reliability ask for installations’ modernization. The constraints imposed to the new lines components refer to the technical aspects as thermal stress or voltage drop, and look for economic efficiency, too. The mechanical sizing of the overhead lines is after all an optimization problem. More precisely, the task in designing of the overhead line profile is to size poles, cross-arms and stays and locate poles along a line route so that the total costs of the line's structure to be minimized and the technical and safety constraints to be fulfilled.The authors present in this paper an application for the Computer-Based Mechanical Design of the Overhead Lines and the features of the corresponding Visual Basic program, adjusted to the distribution lines. The constraints of the optimization problem are adjusted to the existing weather and loading conditions of Romania. The outputs of the software application for mechanical design of overhead lines are: the list of components chosen for the line: poles, cross-arms, stays; the list of conductor tension and forces for each pole, cross-arm and stay for different weather conditions; the line profile drawings.The main features of the mechanical overhead lines design software are interactivity, local optimization function and high-level user-interface

  15. Representativeness of the LifeLines Cohort Study

    NARCIS (Netherlands)

    Klijs, B.; Scholtens, S.; Mandemakers, J.J.; Snieder, H.; Stolk, R.P.; Smidt, N.

    2015-01-01

    Background LifeLines is a large prospective population-based three generation cohort study in the north of the Netherlands. Different recruitment strategies were adopted: recruitment of an index population via general practitioners, subsequent inclusion of their family members, and online

  16. Ground-based transmission line conductor motion sensor

    International Nuclear Information System (INIS)

    Jacobs, M.L.; Milano, U.

    1988-01-01

    A ground-based-conductor motion-sensing apparatus is provided for remotely sensing movement of electric-power transmission lines, particularly as would occur during the wind-induced condition known as galloping. The apparatus is comprised of a motion sensor and signal-generating means which are placed underneath a transmission line and will sense changes in the electric field around the line due to excessive line motion. The detector then signals a remote station when a conditioning of galloping is sensed. The apparatus of the present invention is advantageous over the line-mounted sensors of the prior art in that it is easier and less hazardous to install. The system can also be modified so that a signal will only be given when particular conditions, such as specific temperature range, large-amplitude line motion, or excessive duration of the line motion, are occurring

  17. A pilot study to assess feasibility of value based pricing in Cyprus through pharmacoeconomic modelling and assessment of its operational framework: sorafenib for second line renal cell cancer.

    Science.gov (United States)

    Petrou, Panagiotis; Talias, Michael A

    2014-01-01

    The continuing increase of pharmaceutical expenditure calls for new approaches to pricing and reimbursement of pharmaceuticals. Value based pricing of pharmaceuticals is emerging as a useful tool and possess theoretical attributes to help health system cope with rising pharmaceutical expenditure. To assess the feasibility of introducing a value-based pricing scheme of pharmaceuticals in Cyprus and explore the integrative framework. A probabilistic Markov chain Monte Carlo model was created to simulate progression of advanced renal cell cancer for comparison of sorafenib to standard best supportive care. Literature review was performed and efficacy data were transferred from a published landmark trial, while official pricelists and clinical guidelines from Cyprus Ministry of Health were utilised for cost calculation. Based on proposed willingness to pay threshold the maximum price of sorafenib for the indication of second line renal cell cancer was assessed. Sorafenib value based price was found to be significantly lower compared to its current reference price. Feasibility of Value Based Pricing is documented and pharmacoeconomic modelling can lead to robust results. Integration of value and affordability in the price are its main advantages which have to be weighed against lack of documentation for several theoretical parameters that influence outcome. Smaller countries such as Cyprus may experience adversities in establishing and sustaining essential structures for this scheme.

  18. Smile line and occlusion: An epidemiological study.

    Science.gov (United States)

    Harati, Mahsa; Mostofi, Shahbaz Naser; Jalalian, Ezzatollah; Rezvani, Gholamreza

    2013-11-01

    The purpose of the present study was to discuss some new concepts of the desirable characteristics of smile tooth display. Due to the increasing application of cosmetic dental treatments, there is an increasing need for better understanding of the esthetic principles. In the present descriptive study, with 212 participants, included were patients with no history of orthodontic treatment, loss or prosthetic replacement of anterior teeth, extracted teeth, lips with asymmetry or a history of trauma. Chi-square test was used to determine possible significances in the relation of smile line to Angle occlusion class, overbite and overjet and arch form. A P level of smile design and overbite, overjet and gender but no statistically significant association was found between the smile design and crossbite, molar Angle classification and arch form. Within the limitations of such studies, it might be concluded that there is a significant and important relation between some occlusal parameters and smile design, which must be considered.

  19. Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.

    Science.gov (United States)

    Romano, Paolo; Manniello, Assunta; Aresu, Ottavia; Armento, Massimiliano; Cesaro, Michela; Parodi, Barbara

    2009-01-01

    The Cell Line Data Base (CLDB) is a well-known reference information source on human and animal cell lines including information on more than 6000 cell lines. Main biological features are coded according to controlled vocabularies derived from international lists and taxonomies. HyperCLDB (http://bioinformatics.istge.it/hypercldb/) is a hypertext version of CLDB that improves data accessibility by also allowing information retrieval through web spiders. Access to HyperCLDB is provided through indexes of biological characteristics and navigation in the hypertext is granted by many internal links. HyperCLDB also includes links to external resources. Recently, an interest was raised for a reference nomenclature for cell lines and CLDB was seen as an authoritative system. Furthermore, to overcome the cell line misidentification problem, molecular authentication methods, such as fingerprinting, single-locus short tandem repeat (STR) profile and single nucleotide polymorphisms validation, were proposed. Since this data is distributed, a reference portal on authentication of human cell lines is needed. We present here the architecture and contents of CLDB, its recent enhancements and perspectives. We also present a new related database, the Cell Line Integrated Molecular Authentication (CLIMA) database (http://bioinformatics.istge.it/clima/), that allows to link authentication data to actual cell lines.

  20. Likelihood-based inference for clustered line transect data

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus; Schweder, Tore

    2006-01-01

    The uncertainty in estimation of spatial animal density from line transect surveys depends on the degree of spatial clustering in the animal population. To quantify the clustering we model line transect data as independent thinnings of spatial shot-noise Cox processes. Likelihood-based inference...

  1. Likelihood-based inference for clustered line transect data

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus Plenge; Schweder, Tore

    The uncertainty in estimation of spatial animal density from line transect surveys depends on the degree of spatial clustering in the animal population. To quantify the clustering we model line transect data as independent thinnings of spatial shot-noise Cox processes. Likelihood-based inference...

  2. Transmission Line Ampacity Improvements of AltaLink Wind Plant Overhead Tie-Lines Using Weather-Based Dynamic Line Rating

    Energy Technology Data Exchange (ETDEWEB)

    Bhattarai, Bishnu P.; Gentle, Jake P.; Hill, Porter; McJunkin, Tim; Myers, Kurt S.; Abbound, Alex; Renwick, Rodger; Hengst, David

    2017-07-01

    Abstract—Overhead transmission lines (TLs) are conventionally given seasonal ratings based on conservative environmental assumptions. Such an approach often results in underutilization of the line ampacity as the worst conditions prevail only for a short period over a year/season. We presents dynamic line rating (DLR) as an enabling smart grid technology that adaptively computes ratings of TLs based on local weather conditions to utilize additional headroom of existing lines. In particular, general line ampacity state solver utilizes measured weather data for computing the real-time thermal rating of the TLs. The performance of the presented method is demonstrated from a field study of DLR technology implementation on four TL segments at AltaLink, Canada. The performance is evaluated and quantified by comparing the existing static and proposed dynamic line ratings, and the potential benefits of DLR for enhanced transmission assets utilization. For the given line segments, the proposed DLR results in real-time ratings above the seasonal static ratings for most of the time; up to 95.1% of the time, with a mean increase of 72% over static rating.

  3. Line impedance estimation using model based identification technique

    DEFF Research Database (Denmark)

    Ciobotaru, Mihai; Agelidis, Vassilios; Teodorescu, Remus

    2011-01-01

    The estimation of the line impedance can be used by the control of numerous grid-connected systems, such as active filters, islanding detection techniques, non-linear current controllers, detection of the on/off grid operation mode. Therefore, estimating the line impedance can add extra functions...... into the operation of the grid-connected power converters. This paper describes a quasi passive method for estimating the line impedance of the distribution electricity network. The method uses the model based identification technique to obtain the resistive and inductive parts of the line impedance. The quasi...

  4. State Estimation-based Transmission line parameter identification

    Directory of Open Access Journals (Sweden)

    Fredy Andrés Olarte Dussán

    2010-01-01

    Full Text Available This article presents two state-estimation-based algorithms for identifying transmission line parameters. The identification technique used simultaneous state-parameter estimation on an artificial power system composed of several copies of the same transmission line, using measurements at different points in time. The first algorithm used active and reactive power measurements at both ends of the line. The second method used synchronised phasor voltage and current measurements at both ends. The algorithms were tested in simulated conditions on the 30-node IEEE test system. All line parameters for this system were estimated with errors below 1%.

  5. Implementation of EPICS based Control System for Radioisotope Beam line

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae-Ha; Ahn, Tae-Sung; Song, Young-Gi; Kwon, Hyeok-Jung; Cho, Yong-Sub [Korea Atomic Energy Research Institute, Gyeongju (Korea, Republic of)

    2015-10-15

    Korea Mult-purpose Accelerator Complex (KOMAC) has been operating 100 MeV proton linear accelerator . For operating 100 MeV linac, various control system has been implemented such as vacuum, power supply, RCCS and etc. KOMAC is operating two beam lines so that clients can use 100 MeV proton beam for their experiment. KOMAC sends beam to beam line and target room using two dipole magnets and several quadrupole magnets. As demand for experiments and Radius Isotope using beam is increased, another beam line is under construction and RI beam line control system is need. To synchronize with KOMAC control system, RI beam line control system is based on Experimental Physics and Industrial control System (EPICS) software. The beam is transported to RI beam line to control magnet power supply and vacuum. Implementation of RI beam line control system is presented and some preliminary results are reported. The base RI beam line control system is implemented. It can control beam direction and vacuum. Comparing archived data and current data, RI beam line and control system will be improved. In the future, scroll pump and gate control system will be implemented using programmable logic controller PLC. RI beam interlock sequence will be added to KOMAC interlock system to protect linac.

  6. Power flow studies of magnetically insulated lines

    International Nuclear Information System (INIS)

    McDaniel, D.H.; Poukey, J.W.; Bergeron, K.D.; VanDevender, J.P.; Johnson, D.L.

    1977-01-01

    The designs for relativistic electron beam accelerators with power levels of 20 to 100 TW are greatly restricted by the inductance of a single diode of reasonable size. This fact leads to modular designs of very large accelerators. One concept uses several small insulators at a large radius arranged around the accelerator center. The total effective inductance is then low, but the energy must then be transported by self-magnetic insulated vacuum lines to the target volume. A triplate vacuum line configuration eases many mechanical support problems and allows more A-K gaps or feeds to be packaged around a given radius. This type of vacuum transmission line was chosen for initial experiments at Sandia. The experiments were conducted on the MITE (Magnetically Insulated Transmission Experiment) accelerator. The water pulse forming lines are connected to a vacuum triplate line through a conventional stacked insulator. Diagnostics on the experiment consisted of: (1) input V; (2) input I; (3) I monitors at the input, middle, and output of both the center conductor and ground plane of the transmission line; (4) magnetic energy analyzer to view peak electron energy in the A-K gap; (5) calorimetry; and (6) Faraday cups to look at electron current flowing across the transmission line. The main goal of the experiment is to obtain input impedance of the transmission line as a function of voltage and to measure electron loss currents. These measurements are compared to theoretical models for the input impedance and energy losses

  7. Representativeness of the LifeLines Cohort Study.

    Directory of Open Access Journals (Sweden)

    Bart Klijs

    Full Text Available LifeLines is a large prospective population-based three generation cohort study in the north of the Netherlands. Different recruitment strategies were adopted: recruitment of an index population via general practitioners, subsequent inclusion of their family members, and online self-registration. Our aim was to investigate the representativeness of the adult study population at baseline and to evaluate differences in the study population according to recruitment strategy.Demographic characteristics of the LifeLines study population, recruited between 2006-2013, were compared with the total adult population in the north of the Netherlands as registered in the Dutch population register. Socioeconomic characteristics, lifestyle, chronic diseases, and general health were further compared with participants of the Permanent Survey of Living Conditions within the region (2005-2011, N = 6,093. Differences according to recruitment strategy were assessed.Compared with the population of the north of the Netherlands, LifeLines participants were more often female, middle aged, married, living in a semi-urban place and Dutch native. Adjusted for differences in demographic composition, in LifeLines a smaller proportion had a low educational attainment (5% versus 14% or had ever smoked (54% versus 66%. Differences in the prevalence of various chronic diseases and low general health scores were mostly smaller than 3%. The age profiles of the three recruitment groups differed due to age related inclusion criteria of the recruitment groups. Other differences according to recruitment strategy were small.Our results suggest that, adjusted for differences in demographic composition, the LifeLines adult study population is broadly representative for the adult population of the north of the Netherlands. The recruitment strategy had a minor effect on the level of representativeness. These findings indicate that the risk of selection bias is low and that risk estimates

  8. Wireless overhead line temperature sensor based on RF cavity resonance

    International Nuclear Information System (INIS)

    Ghafourian, Maryam; Nezhad, Abolghasem Zeidaabadi; Bridges, Greg E; Thomson, Douglas J

    2013-01-01

    The importance of maximizing power transfer through overhead transmission lines necessitates the use of dynamic power control to keep transmission line temperatures within acceptable limits. Excessive conductor operating temperatures lead to an increased sag of the transmission line conductor and may reduce their expected life. In this paper, a passive wireless sensor based on a resonant radio frequency (RF) cavity is presented which can be used to measure overhead transmission line temperature. The temperature sensor does not require a power supply and can be easily clamped to the power line with an antenna attached. Changing temperature causes a change of cavity dimensions and a shift in resonant frequency. The resonant frequency of the cavity can be interrogated wirelessly. This temperature sensor has a resolution of 0.07 °C and can be interrogated from distances greater than 4.5 m. The sensor has a deviation from linearity of less than 2 °C. (paper)

  9. WE-EF-303-06: Feasibility of PET Image-Based On-Line Proton Beam-Range Verification with Simulated Uniform Phantom and Human Brain Studies

    International Nuclear Information System (INIS)

    Lou, K; Sun, X; Zhu, X; Grosshans, D; Clark, J; Shao, Y

    2015-01-01

    Purpose: To study the feasibility of clinical on-line proton beam range verification with PET imaging Methods: We simulated a 179.2-MeV proton beam with 5-mm diameter irradiating a PMMA phantom of human brain size, which was then imaged by a brain PET with 300*300*100-mm 3 FOV and different system sensitivities and spatial resolutions. We calculated the mean and standard deviation of positron activity range (AR) from reconstructed PET images, with respect to different data acquisition times (from 5 sec to 300 sec with 5-sec step). We also developed a technique, “Smoothed Maximum Value (SMV)”, to improve AR measurement under a given dose. Furthermore, we simulated a human brain irradiated by a 110-MeV proton beam of 50-mm diameter with 0.3-Gy dose at Bragg peak and imaged by the above PET system with 40% system sensitivity at the center of FOV and 1.7-mm spatial resolution. Results: MC Simulations on the PMMA phantom showed that, regardless of PET system sensitivities and spatial resolutions, the accuracy and precision of AR were proportional to the reciprocal of the square root of image count if image smoothing was not applied. With image smoothing or SMV method, the accuracy and precision could be substantially improved. For a cylindrical PMMA phantom (200 mm diameter and 290 mm long), the accuracy and precision of AR measurement could reach 1.0 and 1.7 mm, with 100-sec data acquired by the brain PET. The study with a human brain showed it was feasible to achieve sub-millimeter accuracy and precision of AR measurement with acquisition time within 60 sec. Conclusion: This study established the relationship between count statistics and the accuracy and precision of activity-range verification. It showed the feasibility of clinical on-line BR verification with high-performance PET systems and improved AR measurement techniques. Cancer Prevention and Research Institute of Texas grant RP120326, NIH grant R21CA187717, The Cancer Center Support (Core) Grant CA016672

  10. Simulation Based Optimization for World Line Card Production System

    Directory of Open Access Journals (Sweden)

    Sinan APAK

    2012-07-01

    Full Text Available Simulation based decision support system is one of the commonly used tool to examine complex production systems. The simulation approach provides process modules which can be adjusted with certain parameters by using data relatively easily obtainable in production process. World Line Card production system simulation is developed to evaluate the optimality of existing production line via using discrete event simulation model with variaty of alternative proposals. The current production system is analysed by a simulation model emphasizing the bottlenecks and the poorly utilized production line. Our analysis identified some improvements and efficient solutions for the existing system.

  11. A study on the development of the on-line operator aid system using rule based expert system and fuzzy logic for nuclear power plants

    International Nuclear Information System (INIS)

    Kang, Ki Sig

    1995-02-01

    The on - line Operator Aid SYStem (OASYS) has been developed to support operator's decision making process and to ensure the safety of nuclear power plants (NPPs) by timely providing operators with proper guidelines according to the plant operation mode. The OASYS consists of four systems such as the signal validation and management system (SVMS), the plant monitoring system (PMS), the alarm filtering and diagnostic system (AFDS), and the dynamic emergency procedure tracking system (DEPTS). The SVMS and the PMS help operators to maintain a plant as a normal operation condition. The AFDS covers the abnormal events until they result in exceeding the limit range of reactor trip signals, while after a reactor trip, the DEPTS aids operators with proper guidelines so as to shutdown safely. The OASYS uses a rule based expert system and a fuzzy logic. The rule based expert system is used to classify the pre-defined events and track the emergency operating procedures (EOPs) through data processing. The fuzzy logic is used to generate the conceptual high level alarms for the prognostic diagnosis and to evaluate the qualitative fuzzy criteria used in EOPs. Performance assessment of the OASYS demonstrates that it is capable of diagnosing plant abnormal conditions and providing operators appropriate guidelines with fast response time and consistency. The developed technology for OASYS will be used to design the Integrated Advanced Control Room in which a plant can be operated by one operator during normal operation. The advanced EOP for emergency operation has been developed by focusing attention on the importance of the operators' role in emergency conditions. To overcome the complexity of current EOPs and maintain the consistency of operators' action according to plant emergency conditions, operator's tasks were allocated according to their duties in the advanced EOP and the computerized operator aid system (COAS) has been developed as an alternative to reduce operator

  12. The Automated Threaded Fastening Based on On-line Identification

    Directory of Open Access Journals (Sweden)

    Nicolas Ivan Giannoccaro

    2008-11-01

    Full Text Available The principle of the thread fastenings have been known and used for decades with the purpose of joining one component to another. Threaded fastenings are popular because they permit easy disassembly for maintenance, repair, relocation and recycling. Screw insertions are typically carried out manually. It is a difficult problem to automat. As a result there is very little published research on automating threaded fastenings, and most research on automated assembly focus on the peg-in-hole assembly problem. This paper investigates the problem of automated monitoring of the screw insertion process. The monitoring problem deals with predicting integrity of a threaded insertion, based on the torque vs. insertion depth curve generated during the insertions. The authors have developed an analytical model to predict the torque signature signals during self-tapping screw insertions. However, the model requires parameters on the screw dimensions and plate material properties are difficult to measure. This paper presents a study on on-line identification during screw fastenings. An identification methodology for two unknown parameter estimation during a self-tapping screw insertion process is presented. It is shown that friction and screw properties required by the model can be reliably estimated on-line. Experimental results are presented to validate the identification procedure.

  13. A mathematical model for camera calibration based on straight lines

    Directory of Open Access Journals (Sweden)

    Antonio M. G. Tommaselli

    2005-12-01

    Full Text Available In other to facilitate the automation of camera calibration process, a mathematical model using straight lines was developed, which is based on the equivalent planes mathematical model. Parameter estimation of the developed model is achieved by the Least Squares Method with Conditions and Observations. The same method of adjustment was used to implement camera calibration with bundles, which is based on points. Experiments using simulated and real data have shown that the developed model based on straight lines gives results comparable to the conventional method with points. Details concerning the mathematical development of the model and experiments with simulated and real data will be presented and the results with both methods of camera calibration, with straight lines and with points, will be compared.

  14. Proton drip-line studies at HRIBF

    International Nuclear Information System (INIS)

    Rykaczewski, K.P.; Batchelder, J.C.; Bingham, C.R.; Bryan, R.E.; Davinson, T.; Woods, P.J.; Ginter, T.N.; Hamilton, J. H.; Gross, C.J.; Grzywacz, R.; Janas, Z.; Karny, M.; MacDonald, B.D.; McConnell, J.W.; Toth, K.S.; Piechaczek, A.; Zganjar, E.F.; Szerypo, J.; Walters, W. B.

    2000-01-01

    Proton radioactivity studies performed at the Holifield Radioactive Ion Beam Facility (HFBR) within the last few years are reviewed. The discovery of five new proton radioactivities 140 Ho, 141m Ho, 145 Tm, 150m Lu and 151m Lu is presented together with a recent observation of fine structure in proton emission from 146gs,m Tm. These proton emitters were produced by means of fusion-evaporation reactions and studied with the HFBR Recoil Mass Separator and detection system based on a Double-sided Silicon Strip Detector. For 113 Cs and 151 Lu, the studies of level structure were extended beyond the proton-emitting states via the measurements with a clover array Clarion using Recoil Decay Tagging

  15. Laser based thermo-conductometry as an approach to determine ribbon solid fraction off-line and in-line.

    Science.gov (United States)

    Wiedey, Raphael; Šibanc, Rok; Kleinebudde, Peter

    2018-06-06

    Ribbon solid fraction is one of the most important quality attributes during roll compaction/dry granulation. Accurate and precise determination is challenging and no in-line measurement tool has been generally accepted, yet. In this study, a new analytical tool with potential off-line as well as in-line applicability is described. It is based on the thermo-conductivity of the compacted material, which is known to depend on the solid fraction. A laser diode was used to punctually heat the ribbon and the heat propagation monitored by infrared thermography. After performing a Gaussian fit of the transverse ribbon profile, the scale parameter σ showed correlation to ribbon solid fraction in off-line as well as in-line studies. Accurate predictions of the solid fraction were possible for a relevant range of process settings. Drug stability was not affected, as could be demonstrated for the model drug nifedipine. The application of this technique was limited when using certain fillers and working at higher roll speeds. This study showed the potentials of this new technique and is a starting point for additional work that has to be done to overcome these challenges. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Photospheric network from study of manganese lines

    Energy Technology Data Exchange (ETDEWEB)

    Elste, G; Teske, R G [Michigan Univ., Ann Arbor (USA). Dept. of Astronomy

    1978-10-01

    Area scans with the multi-channel magnetograph at the Kitt Peak McMath Telescope provided simultaneous measures of equivalent widths in two Mn lines, continuum intensity and longitudinal magnetic field component. Observations were carried out with apertures of 2.5 X 3.5 seconds arc and 1 X 1 seconds arc. For the network elements, which were identified using the magnetic field as tracer, the authors developed relationships between Isub(continuum), Wsub(lambda), Vsub(Doppler) and longitudinal field strength. With a minimum of assumptions it is possible to write from these observed relations an expression connecting true temperature perturbation in the line forming layers of the network to true longitudinal field strength. The results provide some constraints upon possible network models.

  17. Study of parameters of simultaneous lasing on two lines sharing an upper level

    International Nuclear Information System (INIS)

    Pikulev, A A

    2002-01-01

    Stationary lasing at two competing lines sharing an upper level is studied. Based on the expressions for the gain obtained earlier, the possible lasing regimes are considered (at one or two lines) and approximate formulas are derived for determining the output power in each line. These formulas are shown to be the generalisation of the Rigrod formula to the case of simultaneous lasing at several lines. (control of laser radiation parameters)

  18. Manufacturing lines under surplus-based control : multiple products and bounded buffers

    NARCIS (Netherlands)

    Starkov, K.; Pogromskiy, A.Y.; Adan, I.J.B.F.

    2015-01-01

    Challenged by the scheduling complexity for production flow processes in industrial facilities, we study the performance of multi-product producing lines. We analyse the performance of multi-product lines that consist a number of machines and bounded buffers with preselected base stock levels. It is

  19. An alternative approach to spectrum base line estimation

    International Nuclear Information System (INIS)

    Bukvic, S.; Spasojevic, Dj.

    2005-01-01

    We present a new form of merit function which measures agreement between a large number of data and the model function with a particular choice of parameters. We demonstrate the efficiency of the proposed merit function on the common problem of finding the base line of a spectrum. When the base line is expected to be a horizontal straight line, the use of minimization algorithms is not necessary, i.e. the solution is achieved in a small number of steps. We discuss the advantages of the proposed merit function in general, when explicit use of a minimization algorithm is necessary. The hardcopy text is accompanied by an electronic archive, stored on the SAE homepage at http://www1.elsevier.com/homepage/saa/sab/content/lower.htm. The archive contains fully functional demo program with tutorial, examples and Visual Basic source code of the key subroutine

  20. A population-based study of first and second-line drug-resistant tuberculosis in a high-burden area of the Mexico/United States border

    Directory of Open Access Journals (Sweden)

    Pola Becerril-Montes

    2013-04-01

    Full Text Available The resistance of 139 Mycobacterium tuberculosis (MTB isolates from the city of Monterrey, Northeast Mexico, to first and second-line anti-TB drugs was analysed. A total of 73 isolates were susceptible and 66 were resistant to anti-TB drugs. Monoresistance to streptomycin, isoniazid (INH and ethambutol was observed in 29 cases. Resistance to INH was found in 52 cases and in 29 cases INH resistance was combined with resistance to two or three drugs. A total of 24 isolates were multidrug-resistant (MDR resistant to at least INH and rifampicin and 11 MDR cases were resistant to five drugs. The proportion of MDR-TB among new TB cases in our target population was 0.72% (1/139 cases. The proportion of MDR-TB among previously treated cases was 25.18% (35/139 cases. The 13 polyresistant and 24 MDR isolates were assayed against the following seven second-line drugs: amikacin (AMK, kanamycin (KAN, capreomycin (CAP, clofazimine (CLF, ethionamide (ETH, ofloxacin (OFL and cycloserine (CLS. Resistance to CLF, OFL or CLS was not observed. Resistance was detected to ETH (10.80% and to AMK (2.70%, KAN (2.70% and CAP (2.70%. One isolate of MDR with primary resistance was also resistant to three second-line drugs. Monterrey has a high prevalence of MDR-TB among previously treated cases and extensively drug-resistant-MTB strains may soon appear.

  1. Design process and modeling studies of SSRL beam line wunder

    International Nuclear Information System (INIS)

    Bachrach, R.Z.; Bringans, R.D.

    1984-01-01

    SSRL Beam Line Wunder will be the first soft X-ray energy range synchrotron radiation beam line specifically designed to exploit the unique aspects of periodic insertion devices in the wiggler-undulator (wunder) regime. Aspects of the development of this beam line are described in this paper and in particular, we discuss the design methodology adopted and emphasize the joint optical, thermal and mechanical optimization studies that were required. (orig.)

  2. Image Mosaic Method Based on SIFT Features of Line Segment

    Directory of Open Access Journals (Sweden)

    Jun Zhu

    2014-01-01

    Full Text Available This paper proposes a novel image mosaic method based on SIFT (Scale Invariant Feature Transform feature of line segment, aiming to resolve incident scaling, rotation, changes in lighting condition, and so on between two images in the panoramic image mosaic process. This method firstly uses Harris corner detection operator to detect key points. Secondly, it constructs directed line segments, describes them with SIFT feature, and matches those directed segments to acquire rough point matching. Finally, Ransac method is used to eliminate wrong pairs in order to accomplish image mosaic. The results from experiment based on four pairs of images show that our method has strong robustness for resolution, lighting, rotation, and scaling.

  3. Geodesy and astrometry by transatlantic long base line interferometry

    International Nuclear Information System (INIS)

    Cannon, W.H.; Langley, R.B.; Petrachenko, W.T.; Kouba, J.

    1979-01-01

    We report geodetic and astrometric results from the analysis of fringe frequency observations from a series of three long base line interferometry (LBI) experiments carried out in 1973 between the 46-m antenna of the Algonquin Radio Observatory, Lake Traverse, Canada, and the 25-m antenna at Chilbolton Field Station, Chilbolton, England. The rms deviation from the mean of the estimates of the length and orientation of the 5251-km equatorial component of the base line from all three experiments is 1.05-m and 0.015'', respectively. The experiments also yielded positions of five extragalactic radio sources. The reported positions, each of which is from only a single experiment, have uncertainties of about 0.2'' in declination (except for low declination sources) and about 0.01 s in right ascension. The LBI determination of the length and orientation of the equatorial component of the base line is compared to the corresponding values derived from Naval Weapons Laboratory 9D (NWL-9D) coorinates for the antennae. The two length measurements agree in scale within quoted experimental errors; however, the NWL-9D coordinate frame is found to be rotated 0.867'' +- 0.1'' to the east relative to the average terrestrial frame of the Bureau Internationale de l'Heure (BIH),(LBI coordinate frame). This is in good agreement with the expected misalignment of 0.65'' +- 0.2''. The differences in the rates of the clocks used at each end of the base line were also determined and compared to Loran-C observations

  4. Transcriptome-based differentiation of closely-related Miscanthus lines.

    Directory of Open Access Journals (Sweden)

    Philippe Chouvarine

    Full Text Available BACKGROUND: Distinguishing between individuals is critical to those conducting animal/plant breeding, food safety/quality research, diagnostic and clinical testing, and evolutionary biology studies. Classical genetic identification studies are based on marker polymorphisms, but polymorphism-based techniques are time and labor intensive and often cannot distinguish between closely related individuals. Illumina sequencing technologies provide the detailed sequence data required for rapid and efficient differentiation of related species, lines/cultivars, and individuals in a cost-effective manner. Here we describe the use of Illumina high-throughput exome sequencing, coupled with SNP mapping, as a rapid means of distinguishing between related cultivars of the lignocellulosic bioenergy crop giant miscanthus (Miscanthus × giganteus. We provide the first exome sequence database for Miscanthus species complete with Gene Ontology (GO functional annotations. RESULTS: A SNP comparative analysis of rhizome-derived cDNA sequences was successfully utilized to distinguish three Miscanthus × giganteus cultivars from each other and from other Miscanthus species. Moreover, the resulting phylogenetic tree generated from SNP frequency data parallels the known breeding history of the plants examined. Some of the giant miscanthus plants exhibit considerable sequence divergence. CONCLUSIONS: Here we describe an analysis of Miscanthus in which high-throughput exome sequencing was utilized to differentiate between closely related genotypes despite the current lack of a reference genome sequence. We functionally annotated the exome sequences and provide resources to support Miscanthus systems biology. In addition, we demonstrate the use of the commercial high-performance cloud computing to do computational GO annotation.

  5. A regression-based Kansei engineering system based on form feature lines for product form design

    Directory of Open Access Journals (Sweden)

    Yan Xiong

    2016-06-01

    Full Text Available When developing new products, it is important for a designer to understand users’ perceptions and develop product form with the corresponding perceptions. In order to establish the mapping between users’ perceptions and product design features effectively, in this study, we presented a regression-based Kansei engineering system based on form feature lines for product form design. First according to the characteristics of design concept representation, product form features–product form feature lines were defined. Second, Kansei words were chosen to describe image perceptions toward product samples. Then, multiple linear regression and support vector regression were used to construct the models, respectively, that predicted users’ image perceptions. Using mobile phones as experimental samples, Kansei prediction models were established based on the front view form feature lines of the samples. From the experimental results, these two predict models were of good adaptability. But in contrast to multiple linear regression, the predict performance of support vector regression model was better, and support vector regression is more suitable for form regression prediction. The results of the case showed that the proposed method provided an effective means for designers to manipulate product features as a whole, and it can optimize Kansei model and improve practical values.

  6. Smile line and occlusion: An epidemiological study

    Directory of Open Access Journals (Sweden)

    Mahsa Harati

    2013-01-01

    Conclusion: Within the limitations of such studies, it might be concluded that there is a significant and important relation between some occlusal parameters and smile design, which must be considered.

  7. A study of the structure and kinematics of the narrow-line region in Seyfert galaxies

    International Nuclear Information System (INIS)

    Veilleux, S.

    1989-01-01

    The results of a high resolution study of the narrow emission line profiles of 16 Seyfert galaxies are presented. It is shown that the line profile parameters published in earlier low resolution studies are sometimes strongly influenced by resolution effects. In spite of these important systematic errors, many of the results derived from low resolution data are confirmed in the high resolution data. The narrow line profiles of Seyfert galaxies have a stronger base relative to core than a Gaussian. Most of the emission lines present a blueward asymmetry in the lower portion of their profile. In some galaxies, the line widths and/or line asymmetries are correlated with the ionization potential and/or critical density of the lines. There is a weak correlation between the line asymmetry and the dust content of the narrow line region (NLR). The large scatter in this relation, the absence of a similar correlation in Seyfert 1 to 1.5 galaxies, and the presence of a blue asymmetry in galaxies with dustfree line-emitting regions suggest that dust obscuration is not the only mechanism responsible for the line asymmetry in active galaxies. An optically-thick disk close to the nucleus is proposed as the other source of line asymmetry. An important result is that the host galaxy is probably playing a role in the kinematics of some of the gas in the NLR. A multicomponent model of the NLR is proposed to explain these results

  8. Airplane Ice Detector Based on a Microwave Transmission Line

    Science.gov (United States)

    Ngo, Phong; Arndt, G. Dickey; Carl, James R.

    2004-01-01

    An electronic instrument that could detect the potentially dangerous buildup of ice on an airplane wing is undergoing development. The instrument is based on a microwave transmission line configured as a capacitance probe: at selected spots, the transmission-line conductors are partly exposed to allow any ice and/or liquid water present at those spots to act as predominantly capacitive electrical loads on the transmission line. These loads change the input impedance of the transmission line, as measured at a suitable excitation frequency. Thus, it should be possible to infer the presence of ice and/or liquid water from measurements of the input impedance and/or electrical parameters related to the input impedance. The sensory transmission line is of the microstrip type and thus thin enough to be placed on an airplane wing without unduly disturbing airflow in flight. The sensory spots are small areas from which the upper layer of the microstrip has been removed to allow any liquid water or ice on the surface to reach the transmission line. The sensory spots are spaced at nominal open-circuit points, which are at intervals of a half wavelength (in the transmission line, not in air) at the excitation frequency. The excitation frequency used in the experiments has been 1 GHz, for which a half wavelength in the transmission line is .4 in. (.10 cm). The figure depicts a laboratory prototype of the instrument. The impedance-related quantities chosen for use in this version of the instrument are the magnitude and phase of the scattering parameter S11 as manifested in the in-phase (I ) and quadrature (Q) outputs of the phase detector. By careful layout of the transmission line (including the half-wavelength sensor spacing), one can ensure that the amplitude and phase of the input to the phase detector keep shifting in the same direction as ice forms on one or more of the sensor areas. Although only one transmission-line sensor strip is used in the laboratory version, in a

  9. Broad line NMR study of modified polypropylene fibres

    International Nuclear Information System (INIS)

    Olcak, D.; Sevcovic, L.; Mucha, L.

    1999-01-01

    Study of drawn fibres prepared from an isostatic polypropylene modified by an ethylene aminoalkylacrylate copolymer has been done using the broad line of 1 H NMR. NMR spectra were measured on the set of fibres prepared with a draw ratio λ from 1 to 5.5 at two temperatures, one of them corresponding to the onset of segmental motion and the other one is the minddle of the temperature interval as determined by decrease of the second moment M 2 . Decomposition of the spectra into elementary components related to the amorphous, intermediate and crystalline regions of partially crystalline polymers has been made. The drawing of the fibres was found to enhance the chain mobility in the amorphous region and to restrain the molecular motion in the intermediate region. Such behaviour well supports conclusions predicted in the earlier study based on the spin-lattice relaxation time T 1 and dynamic mechanical data treated using the WLF theory. (Authors)

  10. Real-world hospital costs for nonchemotherapy drugs and nondrug care associated with platinum-based doublets in the first-line setting for advanced nonsquamous non-small-cell lung cancer in Chinese patients: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Chen JH

    2016-04-01

    Full Text Available Jianhua Chen,1 Shengqi Wu,2 Chenping Hu,3 Yicheng Yang,4 Narayan Rajan,5 Yun Chen,4 Canjuan Yang,6 Jianfeng Li,6 Wendong Chen7 1Department of Medical Oncology, 2Department of Research and Education, Hunan Province Tumor Hospital, 3Department of Respiratory, Xiangya Hospital, Central South University, Changsha, Hunan, 4Lilly Suzhou Pharmaceutical Co., Ltd. Shanghai Branch, Shanghai, People's Republic of China; 5Global Health Outcomes Research, Eli Lilly and Co, Indianapolis, IN, USA; 6Division of Health Outcome Research, Normin Health Changsha Representative Office, Changsha, Hunan, People's Republic of China; 7Normin Health, Toronto, ON, Canada Objective: The objective of this study was to compare hospital costs per treatment cycle (HCTC for nonchemotherapy drugs and nondrug care associated with platinum-based doublets in the first-line setting for advanced nonsquamous non-small-cell lung cancer (AdvNS-NSCLC in Chinese patients. Methods: Patients receiving platinum-based doublets in the first-line setting for AdvNS-NSCLC from 2010 to 2012 in two Chinese tertiary hospitals were identified to create the retrospective study cohort. Propensity score methods were used to create matched treatment groups for head-to-head comparisons on HCTC between pemetrexed–platinum and other platinum-based doublets. Multiple linear regression analyses were performed to rank studied platinum-based doublets for their associations with the log10 scale of HCTC for nonchemotherapy drugs and nondrug care. Results: Propensity score methods created matched treatment groups for pemetrexed–platinum versus docetaxel–platinum (61 pairs, paclitaxel–platinum (39 pairs, gemcitabine–platinum (93 pairs, and vinorelbine–platinum (73 pairs, respectively. Even though the log10 scale of HCTC for nonchemotherapy drugs and nondrug care associated with pemetrexed–platinum was ranked lowest in all patients (coefficient –0.174, P=0.015, which included patients experiencing

  11. Synthesis and characterization of Cu(II)-based anticancer chemotherapeutic agent targeting topoisomerase Iα: in vitro DNA binding, pBR322 cleavage, molecular docking studies and cytotoxicity against human cancer cell lines.

    Science.gov (United States)

    Tabassum, Sartaj; Zaki, Mehvash; Afzal, Mohd; Arjmand, Farukh

    2014-03-03

    New metal-based anticancer chemotherapeutic drug candidates [Cu(phen)L](NO₃)₂ (1) and [Zn(phen)L](NO₃)₂ (2) were synthesized from ligand L (derived from pharmacophore scaffold barbituric acid and pyrazole). In vitro DNA binding studies of the L, 1 and 2 were carried out by various biophysical techniques revealing electrostatic mode. Complex 1 cleaves pBR322 DNA via oxidative pathway and recognizes major groove of DNA double helix. The molecular docking study was carried out to ascertain the mode of action towards the molecular target DNA and enzymes. The complex 1 exhibited remarkably good anticancer activity on a panel of human cancer cell lines (GI₅₀ values < 10 μg/ml), and to elucidate the mechanism of cancer inhibition, Topo-I enzymatic activity was carried out. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  12. Everolimus plus exemestane versus bevacizumab-based chemotherapy for second-line treatment of hormone receptor-positive metastatic breast cancer in Greece: An economic evaluation study.

    Science.gov (United States)

    Kourlaba, Georgia; Rapti, Vasiliki; Alexopoulos, Athanasios; Relakis, John; Koumakis, Georgios; Chatzikou, Magdalini; Maniadakis, Nikos; Georgoulias, Vassilis

    2015-08-05

    The objective of our study was to conduct a cost-effectiveness (CE) study of combined everolimus (EVE) and exemestane (EXE) versus the common clinical practice in Greece for the treatment of postmenopausal women with HR+/HER2- advanced breast cancer (BC) progressing on nonsteroidal aromatase inhibitors (NSAI). The combinations of bevacizumab (BEV) plus paclitaxel (PACL) and BEV plus capecitabine (CAPE) were selected as comparators. A Markov model, consisting of three health states, was used to describe disease progression and evaluate the CE of the comparators from a third-party payer perspective over a lifetime horizon. Efficacy and safety data as well as utility values considered in the model were extracted from the relevant randomized Phase III clinical trials and other published studies. Direct medical costs referring to the year 2014 were incorporated in the model. A probabilistic sensitivity analysis was conducted to account for uncertainty and variation in the parameters of the model. Primary outcomes were patient survival (life-years), quality-adjusted life years (QALYs), total direct costs and incremental cost-effectiveness ratios (ICER). The discounted quality-adjusted survival of patients treated with EVE plus EXE was greater by 0.035 and 0.004 QALYs, compared to BEV plus PACL and BEV plus CAPE, respectively. EVE plus EXE was the least costly treatment in terms of drug acquisition, administration, and concomitant medications. The total lifetime cost per patient was estimated at €55,022, €67,980, and €62,822 for EVE plus EXE, BEV plus PACL, and BEV plus CAPE, respectively. The probabilistic analysis confirmed the deterministic results. Our results suggest that EVE plus EXE may be a dominant alternative relative to BEV plus PACL and BEV plus CAPE for the treatment of HR+/HER2- advanced BC patients failing initial therapy with NSAIs.

  13. A Continuation of Base-Line Studies for Environmentally Monitoring Space Transportation System (STS) at John F. Kennedy Space Center. Volume 1; Terrestrial Community Analysis

    Science.gov (United States)

    Stout, I. J.

    1979-01-01

    Vegetation and small mammal populations in or around the Merritt Island area were studied. Thirty sites were selected from plant communities which were relatively free of logging, grazing, and clearing operations. The vegetative analysis was designed to yield a quantitative description and ecological explanation of the major types of upland vegetation in order to determine the possible future effects of NASA space activities on them. Changes in the relative abundance of small mammal populations, species diversity, standing crop biomass, reproductive activity, and other demographic features were documented in order to gather sufficient information on these populations so that it would be possible to detect even the smaller nonnatural behavior changes in the mammals which might be attributable to NASA space activities.

  14. A simulation-based approach for solving assembly line balancing problem

    Science.gov (United States)

    Wu, Xiaoyu

    2017-09-01

    Assembly line balancing problem is directly related to the production efficiency, since the last century, the problem of assembly line balancing was discussed and still a lot of people are studying on this topic. In this paper, the problem of assembly line is studied by establishing the mathematical model and simulation. Firstly, the model of determing the smallest production beat under certain work station number is anysized. Based on this model, the exponential smoothing approach is applied to improve the the algorithm efficiency. After the above basic work, the gas stirling engine assembly line balancing problem is discussed as a case study. Both two algorithms are implemented using the Lingo programming environment and the simulation results demonstrate the validity of the new methods.

  15. Radiological reference base line establishment around CENM site

    International Nuclear Information System (INIS)

    Elkhoukhi, T.; Dehbi, N.; Amechmachi, N.

    2008-01-01

    Full text: As for any installation presenting risks for its surrounding, CENM (Centre d'Etudes Nucleaires de Maamora) that accommodates TRIGA Mark II Research Reactor and related laboratories is subjected to a statutory requirement stipulating that the CNESTEN (Centre National De L'Energie Des Sciences Et Des Techniques Nucleaires) that is in charge the operating of CENM must define its own environmental monitoring program assuring that the nuclear installation is in appropriateness with its environment. In this frame , since 1996 the team of USE (Unite Surveillance de L'Environnement) is conducting periodic work consisting in in-situ measurement of ambient gamma rays and collect of environmental samples and their preparation for adequate analysis form required for each radioactive measurement system. This first step of the environmental monitoring program allows establishing the radiological base line on the CENM's site. This base line is necessary to inform on the present radiological state in order to detect any change of this state consequently to the operating of the reactor or the arrival of abnormal radioactive panache from any source.

  16. Ac irreversibility line of bismuth-based high temperature superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Mehdaoui, A. [Laboratoire de Physique et de Spectroscopie Electronique, URA 1435 Faculte des Sciences, Universite de Haute Alsace 4, rue des Freres Lumiere, 68093 Mulhouse Cedex (France); Beille, J. [Laboratoire Louis Neel, CNRS, BP 166, 38042 Grenoble Cedex 9 (France); Berling, D.; Loegel, B. [Laboratoire de Physique et de Spectroscopie Electronique, URA 1435 Faculte des Sciences, Universite de Haute Alsace 4, rue des Freres Lumiere, 68093 Mulhouse Cedex (France); Noudem, J.G.; Tournier, R. [EPM-MATFORMAG, Laboratoire dElaboration par Procede Magnetique, CNRS, BP 166, 38042 Grenoble Cedex 9 (France)

    1997-09-01

    We discuss the magnetic properties of lead doped Bi-2223 bulk samples obtained through combined magnetic melt texturing and hot pressing (MMTHP). The ac complex susceptibility measurements are achieved over a broad ac field range (1 Oe{lt}h{sub ac}{lt}100 Oe) and show highly anisotropic properties. The intergranular coupling is improved in the direction perpendicular to the applied stress and magnetic field direction, and an intragranular loss peak is observed for the first time. A comparison is made with other bismuth-based compounds and it is shown that the MMTHP process shifts the ac irreversibility line (ac IL) toward higher fields. It is also shown that all the ac IL{close_quote}s for quasi 2D bismuth-based compounds show a nearly quadratic temperature dependence and deviate therefore strongly from the linear behavior observed in quasi 3D compounds and expected from a critical state model.{copyright} {ital 1997 Materials Research Society.}

  17. Ac irreversibility line of bismuth-based high temperature superconductors

    International Nuclear Information System (INIS)

    Mehdaoui, A.; Beille, J.; Berling, D.; Loegel, B.; Noudem, J.G.; Tournier, R.

    1997-01-01

    We discuss the magnetic properties of lead doped Bi-2223 bulk samples obtained through combined magnetic melt texturing and hot pressing (MMTHP). The ac complex susceptibility measurements are achieved over a broad ac field range (1 Oe ac <100 Oe) and show highly anisotropic properties. The intergranular coupling is improved in the direction perpendicular to the applied stress and magnetic field direction, and an intragranular loss peak is observed for the first time. A comparison is made with other bismuth-based compounds and it is shown that the MMTHP process shifts the ac irreversibility line (ac IL) toward higher fields. It is also shown that all the ac IL close-quote s for quasi 2D bismuth-based compounds show a nearly quadratic temperature dependence and deviate therefore strongly from the linear behavior observed in quasi 3D compounds and expected from a critical state model.copyright 1997 Materials Research Society

  18. Base line studies North Sea wind farms

    NARCIS (Netherlands)

    Krijgsveld, K.L.; Lieshout, S.M.J.; Schekkerman, H.; Lensink, Rick; Poot, M.J.M.; Dirksen, S.

    2003-01-01

    The Dutch government has granted ‘Noordzeewind’ (Nuon Renewable Energy Projects and Shell Wind Energy) the possibility to build a wind farm consisting of 36 wind turbines off the coast of the Netherlands, near Egmond. This project serves to evaluate the economical, technical, ecological and social

  19. 19 CFR 142.50 - Line Release data base corrections or changes.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Line Release data base corrections or changes. 142...; DEPARTMENT OF THE TREASURY (CONTINUED) ENTRY PROCESS Line Release § 142.50 Line Release data base corrections... numbers or bond information on a Line Release Data Loading Sheet as soon as possible. Notification shall...

  20. Study of effect of in-line hydropneumatic accumulators on output characteristics of hydraulic hammer

    Science.gov (United States)

    Redelin, R. A.; Kravchenko, V. A.; Kamanin, Y. N.; Panichkin, A. V.; Bozhanov, A. A.

    2017-10-01

    The article presents the results of studies of the effect of in-line hydropneumatic accumulators on the output parameters of a hydraulic hammer during their joint operation. Based on mathematical modeling, computational experiments were performed and the output characteristics of the hammer, depending on the design and operating parameters of the in-line hydropneumatic accumulators, were obtained. It was established that for the most effective operation of the hammer, the precharge pressure of the pressure line hydropneumatic accumulator should be 70-80% of the working pressure of the hydraulic system. The utilization of a hydropneumatic accumulator without special additional devices in the discharge line is impractical.

  1. Molecular dynamics study of the nanosized droplet spreading: The effect of the contact line forces on the kinetic energy dissipation

    International Nuclear Information System (INIS)

    Yoon, Hong Min; Kondaraju, Sasidhar; Lee, Jung Shin; Suh, Youngho; Lee, Joonho H.; Lee, Joon Sang

    2017-01-01

    Highlights: • Contact line forces, including friction and spreading forces are directly calculated. • Overall trends of variations in contact line forces during droplet spreading process show characteristics of contact line forces. • Detail relations of contact line forces and atomic kinetics in the contact line provide a clear evidence of the possible energy dissipation mechanism in droplet spreading process. - Abstract: Recent studies have revealed that contact line forces play an important role in the droplet spreading process. Despite their significance, the physics related to them has been studied only indirectly and the effect of contact line forces is still being disputed. We performed a molecular dynamics simulation and mimicked the droplet spreading process at the nanoscale. Based on the results of the simulation, the contact line forces were directly calculated. We found that the forces acting on the bulk and the contact line region showed different trends. Distinct positive and negative forces, contact line spreading, and friction forces were observed near the contact line. We also observed a strong dependency of the atomic kinetics in the contact line region on the variations in the contact line forces. The atoms of the liquid in the contact line region lost their kinetic energy due to the contact line friction force and became partially immobile on the solid surface. The results of the current study will be useful for understanding the role of the contact line forces on the kinetic energy dissipation in the contact line region.

  2. Molecular dynamics study of the nanosized droplet spreading: The effect of the contact line forces on the kinetic energy dissipation

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Hong Min [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of); Kondaraju, Sasidhar [Department of Mechanical Science, Indian Institute of Technology Bhubaneswar, Bhubaneswar, Odisha 751013 (India); Lee, Jung Shin [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of); Suh, Youngho; Lee, Joonho H. [Samsung Electronics, Mechatronics R& D Center, Hwaseong-si, Gyeonggi-do 445-330 (Korea, Republic of); Lee, Joon Sang, E-mail: joonlee@yonsei.ac.kr [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of)

    2017-07-01

    Highlights: • Contact line forces, including friction and spreading forces are directly calculated. • Overall trends of variations in contact line forces during droplet spreading process show characteristics of contact line forces. • Detail relations of contact line forces and atomic kinetics in the contact line provide a clear evidence of the possible energy dissipation mechanism in droplet spreading process. - Abstract: Recent studies have revealed that contact line forces play an important role in the droplet spreading process. Despite their significance, the physics related to them has been studied only indirectly and the effect of contact line forces is still being disputed. We performed a molecular dynamics simulation and mimicked the droplet spreading process at the nanoscale. Based on the results of the simulation, the contact line forces were directly calculated. We found that the forces acting on the bulk and the contact line region showed different trends. Distinct positive and negative forces, contact line spreading, and friction forces were observed near the contact line. We also observed a strong dependency of the atomic kinetics in the contact line region on the variations in the contact line forces. The atoms of the liquid in the contact line region lost their kinetic energy due to the contact line friction force and became partially immobile on the solid surface. The results of the current study will be useful for understanding the role of the contact line forces on the kinetic energy dissipation in the contact line region.

  3. Extracting potential bus lines of Customized City Bus Service based on public transport big data

    Science.gov (United States)

    Ren, Yibin; Chen, Ge; Han, Yong; Zheng, Huangcheng

    2016-11-01

    Customized City Bus Service (CCBS) can reduce the traffic congestion and environmental pollution that caused by the increasing in private cars, effectively. This study aims to extract the potential bus lines and each line's passenger density of CCBS by mining the public transport big data. The datasets used in this study are mainly Smart Card Data (SCD) and bus GPS data of Qingdao, China, from October 11th and November 7th 2015. Firstly, we compute the temporal-origin-destination (TOD) of passengers by mining SCD and bus GPS data. Compared with the traditional OD, TOD not only has the spatial location, but also contains the trip's boarding time. Secondly, based on the traditional DBSCAN algorithm, we put forwards an algorithm, named TOD-DBSCAN, combined with the spatial-temporal features of TOD.TOD-DBSCAN is used to cluster the TOD trajectories in peak hours of all working days. Then, we define two variables P and N to describe the possibility and passenger destiny of a potential CCBS line. P is the probability of the CCBS line. And N represents the potential passenger destiny of the line. Lastly, we visualize the potential CCBS lines extracted by our procedure on the map and analyse relationship between potential CCBS lines and the urban spatial structure.

  4. Genomic prediction based on data from three layer lines using non-linear regression models.

    Science.gov (United States)

    Huang, Heyun; Windig, Jack J; Vereijken, Addie; Calus, Mario P L

    2014-11-06

    Most studies on genomic prediction with reference populations that include multiple lines or breeds have used linear models. Data heterogeneity due to using multiple populations may conflict with model assumptions used in linear regression methods. In an attempt to alleviate potential discrepancies between assumptions of linear models and multi-population data, two types of alternative models were used: (1) a multi-trait genomic best linear unbiased prediction (GBLUP) model that modelled trait by line combinations as separate but correlated traits and (2) non-linear models based on kernel learning. These models were compared to conventional linear models for genomic prediction for two lines of brown layer hens (B1 and B2) and one line of white hens (W1). The three lines each had 1004 to 1023 training and 238 to 240 validation animals. Prediction accuracy was evaluated by estimating the correlation between observed phenotypes and predicted breeding values. When the training dataset included only data from the evaluated line, non-linear models yielded at best a similar accuracy as linear models. In some cases, when adding a distantly related line, the linear models showed a slight decrease in performance, while non-linear models generally showed no change in accuracy. When only information from a closely related line was used for training, linear models and non-linear radial basis function (RBF) kernel models performed similarly. The multi-trait GBLUP model took advantage of the estimated genetic correlations between the lines. Combining linear and non-linear models improved the accuracy of multi-line genomic prediction. Linear models and non-linear RBF models performed very similarly for genomic prediction, despite the expectation that non-linear models could deal better with the heterogeneous multi-population data. This heterogeneity of the data can be overcome by modelling trait by line combinations as separate but correlated traits, which avoids the occasional

  5. Manufacturing system design based on axiomatic design: Case of assembly line

    Energy Technology Data Exchange (ETDEWEB)

    Hager, T.; Wafik, H.; Faouzi, M.

    2017-07-01

    In this paper, a combined Production Line Design (PLD) process which includes many design aspects is presented, developed and validated. Design/methodology/approach: The PLD process is based on the SADT (Structured Analysis and Design Technique) diagram and the Axiomatic Design (AD) method. Practical implications: For a purpose of validation, this proposed process has been applied in a manufacturing company and it has been validated by simulation. Findings: The results of the validation indicated that the production line designed by this process is outperformed the initial line of the company. Originality/value: Recently, the problems of production line design (PLD) have attracted the attention of many researchers. However, only a few studies have treated the PLD which includes all design aspects. In this work, a combined PLD process is presented. It should be noted that the proposed process is simple and effective.

  6. Manufacturing system design based on axiomatic design: Case of assembly line

    International Nuclear Information System (INIS)

    Hager, T.; Wafik, H.; Faouzi, M.

    2017-01-01

    In this paper, a combined Production Line Design (PLD) process which includes many design aspects is presented, developed and validated. Design/methodology/approach: The PLD process is based on the SADT (Structured Analysis and Design Technique) diagram and the Axiomatic Design (AD) method. Practical implications: For a purpose of validation, this proposed process has been applied in a manufacturing company and it has been validated by simulation. Findings: The results of the validation indicated that the production line designed by this process is outperformed the initial line of the company. Originality/value: Recently, the problems of production line design (PLD) have attracted the attention of many researchers. However, only a few studies have treated the PLD which includes all design aspects. In this work, a combined PLD process is presented. It should be noted that the proposed process is simple and effective.

  7. Dynamics of contact line depinning during droplet evaporation based on thermodynamics.

    Science.gov (United States)

    Yu, Dong In; Kwak, Ho Jae; Doh, Seung Woo; Ahn, Ho Seon; Park, Hyun Sun; Kiyofumi, Moriyama; Kim, Moo Hwan

    2015-02-17

    For several decades, evaporation phenomena have been intensively investigated for a broad range of applications. However, the dynamics of contact line depinning during droplet evaporation has only been inductively inferred on the basis of experimental data and remains unclear. This study focuses on the dynamics of contact line depinning during droplet evaporation based on thermodynamics. Considering the decrease in the Gibbs free energy of a system with different evaporation modes, a theoretical model was developed to estimate the receding contact angle during contact line depinning as a function of surface conditions. Comparison of experimentally measured and theoretically modeled receding contact angles indicated that the dynamics of contact line depinning during droplet evaporation was caused by the most favorable thermodynamic process encountered during constant contact radius (CCR mode) and constant contact angle (CCA mode) evaporation to rapidly reach an equilibrium state during droplet evaporation.

  8. Exploring Students’ Intention to Use LINE for Academic Purposes Based on Technology Acceptance Model

    Directory of Open Access Journals (Sweden)

    Willard Van De Bogart

    2015-06-01

    Full Text Available The LINE application is often conceived as purely social space; however, the authors of this paper wanted to determine if it could be used for academic purposes. In this study, we examined how undergraduate students accepted LINE in terms of using it for classroom-related activities (e.g., submit homework, follow up course information queries, download materials and explored the factors that might affect their intention to use it. Data were collected from 144 undergraduate students enrolled in an English course that utilized some activities based on LINE app using a questionnaire developed from TAM. Data were analyzed to see if relationships existed among factors when LINE was used to organize classroom experiences. The findings revealed that perceived usefulness and attitude toward usage had positive relationships with intention to use while perceived ease of use was positively related to perceived usefulness. In contrast with TAM assertions, this study did not find any relationship between perceived ease of use and attitude toward usage. Also, the number of social networking sites that students are using had no relationship with intention to use. The study also suggested some kinds of LINE-based learning activities preferred by students, which would be proposed for future courses. This study revealed several useful implications that TAM can be employed as a useful theoretical framework to predict and understand users’ intention to use new technologies in education.

  9. Healthy Checkout Lines: A Study in Urban Supermarkets.

    Science.gov (United States)

    Adjoian, Tamar; Dannefer, Rachel; Willingham, Craig; Brathwaite, Chantelle; Franklin, Sharraine

    2017-09-01

    To understand the impact of healthy checkouts in Bronx, New York City supermarkets. Consumer purchasing behavior was observed for 2 weeks in 2015. Three supermarkets in the South Bronx. A total of 2,131 adult shoppers (aged ≥18 years) who paid for their groceries at 1 of the selected study checkout lines. Two checkout lines were selected per store; 1 was converted to a healthy checkout and the other remained as it was (standard checkout). Data collectors observed consumer behavior at each line and recorded items purchased from checkout areas. Percentage of customers who purchase items from the checkout area; quantity and price of healthy and unhealthy items purchased from the healthy and standard checkout lines. Measures were analyzed by study condition using chi-square and t tests; significance was determined at α = .05. Only 4.0% of customers bought anything from the checkout area. A higher proportion of customers using the healthy vs standard checkout line bought healthy items (56.5% vs 20.5%; P < .001). When healthier products were available, the proportion of healthy purchases increased. Findings contribute to limited research on effectiveness of healthy checkouts in supermarkets. Similar interventions should expect an increase in healthy purchases from the checkout area, but limited overall impact. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  10. Knowledge-based on-line vibration monitoring diagnose

    International Nuclear Information System (INIS)

    Johansson, L.G.; Karlsson, A.; Noeremark, A.

    1990-01-01

    ABB STAL developed some years ago a knowledge-based on-line vibration analysis system (working-name KOVA). KOVA is intended to work together with some type of vibration monitoring system, at present it is adapted to TVM 300. KOVA has no controlling function. It will only diagnose the actual situation and give the user explanations and proposals for actions to be taken. During the developing work, great experience has been gained of the features this type of system demands. This paper will present the outlines of the application and also discuss how to make diagnoses based both on general rules as well as on historical vibration cases for that particular unit (or identical units9. Another subject that this paper will outline, is the representation and evaluation of knowledge. KOVA serves as a decision-support system for the operator. Since KOVA will often give the operator more than one possible diagnosis as the cause of a fault, it is of great importance to give the operator comprehensive explanations and as many facts as possible. It is also important to rank the suggested diagnoses in some way. In KOVA these demands are effectively supported. The models and tools used to realize this functionality will be described in this paper

  11. FURTHER CONSIDERATIONS ON SPREADSHEET-BASED AUTOMATIC TREND LINES

    Directory of Open Access Journals (Sweden)

    DANIEL HOMOCIANU

    2015-12-01

    Full Text Available Most of the nowadays business applications working with data sets allow exports to the spreadsheet format. This fact is related to the experience of common business users with such products and to the possibility to couple what they have with something containing many models, functions and possibilities to process and represent data, by that getting something in dynamics and much more than a simple static less useful report. The purpose of Business Intelligence is to identify clusters, profiles, association rules, decision trees and many other patterns or even behaviours, but also to generate alerts for exceptions, determine trends and make predictions about the future based on historical data. In this context, the paper shows some practical results obtained after testing both the automatic creation of scatter charts and trend lines corresponding to the user’s preferences and the automatic suggesting of the most appropriate trend for the tested data mostly based on the statistical measure of how close they are to the regression function.

  12. A Multilayer Perceptron-Based Impulsive Noise Detector with Application to Power-Line-Based Sensor Networks

    KAUST Repository

    Chien, Ying-Ren; Chen, Jie-Wei; Xu, Sendren Sheng-Dong

    2018-01-01

    For power-line-based sensor networks, impulsive noise (IN) will dramatically degrade the data transmission rate in the power line. In this paper, we present a multilayer perceptron (MLP)-based approach to detect IN in orthogonal frequency

  13. Study of the Auger line shape of polyethylene and diamond

    Energy Technology Data Exchange (ETDEWEB)

    Dayan, M; Pepper, S V

    1984-03-01

    The KVV Auger electron line shapes of carbon in polyethylene and diamond have been studied. The spectra were obtained in derivative form by electron beam excitation. They were treated by background subtraction, integration and deconvolution to produce the intrinsic Auger line shape. Electron energy loss spectra provided the response function in the deconvolution procedure. The line shape from polyethylene is compared with spectra from linear alkanes and with a previous spectrum of Kelber et al. Both spectra are compared with the self-convolution of their full valence band densities of states and of their p-projected densities. The experimental spectra could not be understood in terms of existing theories. This is so even when correlation effects are qualitatively taken into account according to the theories of Cini and Sawatzky and Lenselink.

  14. A study of the flow field surrounding interacting line fires

    Science.gov (United States)

    Trevor Maynard; Marko Princevac; David R. Weise

    2016-01-01

    The interaction of converging fires often leads to significant changes in fire behavior, including increased flame length, angle, and intensity. In this paper, the fluid mechanics of two adjacent line fires are studied both theoretically and experimentally. A simple potential flow model is used to explain the tilting of interacting flames towards each other, which...

  15. Study on the wiping gas jet in continuous galvanizing line

    Science.gov (United States)

    Kweon, Yong-Hun; Kim, Heuy-Dong

    2011-09-01

    In the continuous hot-dip galvanizing process, the gas-jet wiping is used to control the coating thickness of moving steel strip. The high speed gas-jet discharged from the nozzle slot impinges on the strip, and at this moment, wipes the liquid coating layer dragged by a moving strip. The coating thickness is generally influenced on the flow characteristics of wiping gas-jet such as the impinging pressure distribution, pressure gradient and shear stress distribution on the surface of strip. The flow characteristics of wiping gas-jet mentioned above depends upon considerably both the process operating conditions such as the nozzle pressure, nozzle-to-strip distance and line speed, and the geometry of gas-jet wiping apparatus such as the height of nozzle slot. In the present study, the effect of the geometry of nozzle on the coating thickness is investigated with the help of a computational fluid dynamics method. The height of nozzle slot is varied in the range of 0.6mm to 1.7mm. A finite volume method (FVM) is employed to solve two-dimensional, steady, compressible Navier-Stokes equations. Based upon the results obtained, the effect of the height of nozzle slot in the gas-jet wiping process is discussed in detail. The computational results show that for a given standoff distance between the nozzle to the strip, the effective height of nozzle slot exists in achieving thinner coating thickness.

  16. Evaluation of different finish line designs in base metal alloys

    Directory of Open Access Journals (Sweden)

    Aghandeh R

    1999-06-01

    Full Text Available This investigation was performed according to the widespread application of base metal alloys"nand few articles published about the marginal integrity of restorations fabricated by these metals."nThree standard dies of a maxillary first premolar were prepared with a flat shoulder finish line in buccal"naspect and chamfer in palatal. One of them left with no change. On the buccal aspect of the second and"nthird dies 135?and 1607 bevel were added respectively"nUsing dual wax technique, nine wax patterns were formed on each die and casting procedure of selected"nnon precious alloy was performed by centrifugal method. Marginal gaps of each copping seated on dies"nwere measured by scanning electron microscope (SEM with X500 magnification. Measurements were"ndone on three areas of marked dies on buccal aspect. Measurement son palatal aspect was done on"nmarked midpalatal point as control."nResults and statistical analysis showed no significant difference among marginal gaps in lingual aspect."nBut on the buccal aspect there were statistically significant differences among the groups (P<0.001. Flat"nshoulder had the best marginal integrity (mean 4 micron. Shoulder with 160' bevel had the most marginal"ngap (mean 26.5 micron and shoulder with 1357 bevel was between two other groups (mean 15.7 micron.

  17. Downward Price-Based Brand Line Extensions Effects on Luxury Brands

    OpenAIRE

    Royo-Vela, Marcelo; Voss, Eileen

    2015-01-01

    This study tries to examine the brand concept consistency, the self-concept congruence and the resulting loyalty status of the consumers in order to evaluate whether a downward price-based line extensions in the luxury goods market has any negative or positive effect on them. By conducting focus group and in-depth interviews it was tried to filter out how brand concepts of luxury brands are perceived before and after a line extension. Results revealed that a crucial aspect for the evaluation ...

  18. Studies on maize inbred lines susceptibility to herbicides

    Directory of Open Access Journals (Sweden)

    Stefanović Lidija

    2010-01-01

    Full Text Available This paper presents the analysis of results obtained during long- term studies on the response of maize inbred lines to herbicides. Under the agroecological conditions of Zemun Polje the response (reaction of maize inbred lines to herbicides of different classes was investigated. Biological tests were performed and some agronomic, morphological, physiological and biochemical parameters were determined when the response of maize inbred lines to herbicides was estimated. The use of active ingredients of herbicides from triazine, acetanilide, thiocarbamate to new chemical groups (sulfonylurea etc., have been resulted in changes in weed suppression and susceptibility of inbred lines. Obtained results show that effects of herbicides on susceptible maize genotypes can be different: they can slowdown the growth and development and affect the plant height; they can also affect the stages of the tassel and ear development and at the end they can reduced grain yield of the tested inbreds. Numerous studies confirmed the existence of differences in susceptibility level of maize genotypes in relation to herbicides. According to gained results the recommendations for growers are made on the possibility of the application of new herbicides in the hybrid seed production.

  19. Analytical methods for study of transmission line lightning protection

    International Nuclear Information System (INIS)

    Pettersson, Per.

    1993-04-01

    Transmission line lightning performance is studied by analytical methods. The elements of shielding failure flashovers and back-flashovers are analysed as functions of incidence, response and insulation. Closed-form approximate expressions are sought to enhance understanding of the phenomena. Probabilistic and wave propagation aspects are particularly studied. The electrogeometric model of lightning attraction to structures is used in combination with the log-normal probability distribution of lightning to ground currents. The log-normality is found to be retained for the currents collected by mast-type as well as line-type structures, but with a change of scale. For both types, exceedingly simple formulas for the number of hits are derived. Simple closed-form expressions for the line outage rates from back- flashovers and shielding failure flashovers are derived in a uniform way as functions of the critical currents. The expressions involve the standardized normal distribution function. System response is analysed by use of Laplace transforms in combination with text-book transmission-line theory. Inversion into time domain is accomplished by an approximate asymptotic method producing closed-form results. The back-flashover problem is analysed in particular. Approximate, image type expressions are derived for shunt admittance of wires above, on and under ground for analyses of fast transients. The derivation parallels that for series impedance, now well-known. 3 refs, 5 figs

  20. Impact on Medical Cost, Cumulative Survival, and Cost-Effectiveness of Adding Rituximab to First-Line Chemotherapy for Follicular Lymphoma in Elderly Patients: An Observational Cohort Study Based on SEER-Medicare

    International Nuclear Information System (INIS)

    Griffiths, R. I.; Gleeson, M. L.; Danese, M. D.; Griffiths, R. I.; Mikhael, J.

    2012-01-01

    Rituximab improves survival in follicular lymphoma (FL), but is considerably more expensive than conventional chemotherapy. We estimated the total direct medical costs, cumulative survival, and cost-effectiveness of adding rituximab to first-line chemotherapy for FL, based on a single source of data representing routine practice in the elderly. Using surveillance, epidemiology, and end results (SEER) registry data plus Medicare claims, we identified 1,117 FL patients who received first-line CHOP (cyclophosphamide (C), doxorubicin, vincristine (V), and prednisone (P)) or CVP +/− rituximab. Multivariate regression was used to estimate adjusted cumulative cost and survival differences between the two groups over four years after beginning treatment. The median age was 73 years (minimum 66 years), 56% had stage III-IV disease, and 67% received rituximab. Adding rituximab to first-line chemotherapy was associated with higher adjusted incremental total cost ($18,695; 95% Confidence Interval (CI) $9,302-$28,643) and longer adjusted cumulative survival (0.18 years; 95% CI 0.10-0.27) over four years of followup. The expected cost-effectiveness was $102,142 (95% CI $34,531-296,337) per life-year gained. In routine clinical practice, adding rituximab to first-line chemotherapy for elderly patients with FL results in higher direct medical costs to Medicare and longer cumulative survival after four years.

  1. Impact on Medical Cost, Cumulative Survival, and Cost-Effectiveness of Adding Rituximab to First-Line Chemotherapy for Follicular Lymphoma in Elderly Patients: An Observational Cohort Study Based on SEER-Medicare

    Directory of Open Access Journals (Sweden)

    Robert I. Griffiths

    2012-01-01

    Full Text Available Rituximab improves survival in follicular lymphoma (FL, but is considerably more expensive than conventional chemotherapy. We estimated the total direct medical costs, cumulative survival, and cost-effectiveness of adding rituximab to first-line chemotherapy for FL, based on a single source of data representing routine practice in the elderly. Using surveillance, epidemiology, and end results (SEER registry data plus Medicare claims, we identified 1,117 FL patients who received first-line CHOP (cyclophosphamide (C, doxorubicin, vincristine (V, and prednisone (P or CVP +/− rituximab. Multivariate regression was used to estimate adjusted cumulative cost and survival differences between the two groups over four years after beginning treatment. The median age was 73 years (minimum 66 years, 56% had stage III-IV disease, and 67% received rituximab. Adding rituximab to first-line chemotherapy was associated with higher adjusted incremental total cost ($18,695; 95% Confidence Interval (CI $9,302–$28,643 and longer adjusted cumulative survival (0.18 years; 95% CI 0.10–0.27 over four years of followup. The expected cost-effectiveness was $102,142 (95% CI $34,531–296,337 per life-year gained. In routine clinical practice, adding rituximab to first-line chemotherapy for elderly patients with FL results in higher direct medical costs to Medicare and longer cumulative survival after four years.

  2. Sensing line effects on PWR-based differential pressure measurements

    International Nuclear Information System (INIS)

    Evans, R.P.; Neff, G.G.

    1982-01-01

    An incorrrect configuration of the fluid-filled pressure sensing lines connecting differential pressure transducers to the pressure taps in a pressurized water reactor system can cause errors in the measurement and, during rapid pressure transients, could cause the transducer to fail. Testing was performed in both static and dynamic modes to experimentally determine the effects of sensing lines of various lengths, diameters, and materials. Testing was performed at ambient temperature with absolute line pressures at about 17 MPa using water as the pressure transmission fluid

  3. Markerless tracking in nuclear power plants. A line segment-based approach

    International Nuclear Information System (INIS)

    Ishii, Hirotake; Kimura, Taro; Tokumaru, Hiroki; Shimoda, Hiroshi; Koda, Yuya

    2017-01-01

    To develop augmented reality-based support systems, a tracking method that measures the camera's position and orientation in real time is indispensable. A relocalization is one step that is used to (re)start the tracking. A line-segment-based relocalization method that uses a RGB-D camera and coarse-to-fine approach was developed and evaluated for this study. In the preparation stage, the target environment is scanned with a RGB-D camera. Line segments are recognized. Then three-dimensional positions of the line segments are calculated, and statistics of the line segments are calculated and stored in a database. In the relocalization stage, a few images that closely resemble the current RGB-D camera image are chosen from the database by comparing the statistics of the line segments. Then the most similar image is chosen using Normalized Cross-Correlation. This coarse-to-fine approach reduces the computational load to find the most similar image. The method was evaluated in the water purification room of the Fugen nuclear power plant. Results showed that the success rate of the relocalization is 93.6% and processing time is 45.7 ms per frame on average, which is promising for practical use. (author)

  4. Theoretical Studies of Spectroscopic Line Mixing in Remote Sensing Applications

    Science.gov (United States)

    Ma, Q.

    2015-12-01

    The phenomenon of collisional transfer of intensity due to line mixing has an increasing importance for atmospheric monitoring. From a theoretical point of view, all relevant information about the collisional processes is contained in the relaxation matrix where the diagonal elements give half-widths and shifts, and the off-diagonal elements correspond to line interferences. For simple systems such as those consisting of diatom-atom or diatom-diatom, accurate fully quantum calculations based on interaction potentials are feasible. However, fully quantum calculations become unrealistic for more complex systems. On the other hand, the semi-classical Robert-Bonamy (RB) formalism, which has been widely used to calculate half-widths and shifts for decades, fails in calculating the off-diagonal matrix elements. As a result, in order to simulate atmospheric spectra where the effects from line mixing are important, semi-empirical fitting or scaling laws such as the ECS and IOS models are commonly used. Recently, while scrutinizing the development of the RB formalism, we have found that these authors applied the isolated line approximation in their evaluating matrix elements of the Liouville scattering operator given in exponential form. Since the criterion of this assumption is so stringent, it is not valid for many systems of interest in atmospheric applications. Furthermore, it is this assumption that blocks the possibility to calculate the whole relaxation matrix at all. By eliminating this unjustified application, and accurately evaluating matrix elements of the exponential operators, we have developed a more capable formalism. With this new formalism, we are now able not only to reduce uncertainties for calculated half-widths and shifts, but also to remove a once insurmountable obstacle to calculate the whole relaxation matrix. This implies that we can address the line mixing with the semi-classical theory based on interaction potentials between molecular absorber and

  5. On-line mixture-based alternative to logistic regression

    Czech Academy of Sciences Publication Activity Database

    Nagy, Ivan; Suzdaleva, Evgenia

    2016-01-01

    Roč. 26, č. 5 (2016), s. 417-437 ISSN 1210-0552 R&D Projects: GA ČR GA15-03564S Institutional support: RVO:67985556 Keywords : on-line modeling * on-line logistic regression * recursive mixture estimation * data dependent pointer Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.394, year: 2016 http://library.utia.cas.cz/separaty/2016/ZS/suzdaleva-0464463.pdf

  6. LINE-BASED REGISTRATION OF DSM AND HYPERSPECTRAL IMAGES

    Directory of Open Access Journals (Sweden)

    J. Avbelj

    2013-04-01

    Full Text Available Data fusion techniques require a good registration of all the used datasets. In remote sensing, images are usually geo-referenced using the GPS and IMU data. However, if more precise registration is required, image processing techniques can be employed. We propose a method for multi-modal image coregistration between hyperspectral images (HSI and digital surface models (DSM. The method is divided in three parts: object and line detection of the same object in HSI and DSM, line matching and determination of transformation parameters. Homogeneous coordinates are used to implement matching and adjustment of transformation parameters. The common object in HSI and DSM are building boundaries. They have apparent change in height and material, that can be detected in DSM and HSI, respectively. Thus, before the matching and transformation parameter computation, building outlines are detected and adjusted in HSI and DSM. We test the method on a HSI and two DSM, using extracted building outbounds and for comparison also extracted lines with a line detector. The results show that estimated building boundaries provide more line assignments, than using line detector.

  7. Magnetic Field Exposure Estimates Based on Power Lines Near Homes (invited paper)

    International Nuclear Information System (INIS)

    Ahlbom, A.; Feychting, M.

    1999-01-01

    Several epidemiological studies have based their estimates of magnetic field exposure on the proximity to power lines. This has been done in three principally different ways, which differ in the amount of information that is used. These are: (1) distance; (2) distance and configuration (wire code); and (3) distance, configuration, and load (calculated field). It is presumed that the more information that is used, the more accurate is the exposure estimate. All these three approaches suffer from the limitation that they only account for exposure that is generated by power lines. The influence on the in-home magnetic field from sources other than the power line are not considered, nor is exposure experienced at places other than the home. This raises the following question. What is the implication for the result of the epidemiological study of the exposure misclassification that is introduced by basing magnetic field exposure estimation on power lines near homes? Although the necessary information is only partly at hand the answers to this question will be discussed. The basis will be some general epidemiological principles combined with data from a Swedish study on residential exposure and cancer risk. (author)

  8. Comparing On-Line to In-Person Course Delivery: An Empirical Study

    Directory of Open Access Journals (Sweden)

    Jammie Price

    2007-05-01

    Full Text Available Web-based technologies have been used in the classroom for over 15 years, including websites, email, listserves, library reserves, and text books. Among these options, social scientists range widely in their web usage – from simply posting syllabi on-line to delivering a course fully on-line in asynchronous learning networks. Use of web-based technology for instructional purposes is increasing, as is enrollment in distance education courses and on-line course offerings. Many administrators and faculty promote on-line instruction as the solution to managing increased college enrollments, particularly among non-traditional students. However, are the academic outcomes of on-line instruction similar to traditional in-person instruction? Few empirical studies have been done. This is unfortunate. The results of an experiment to evaluate the relative effectiveness of on-line verses an in-person course on sociological research are presented. Unfortunately the on-line participants did much worse than the in-person course.

  9. Line identification studies using traditional techniques and wavelength coincidence statistics

    International Nuclear Information System (INIS)

    Cowley, C.R.; Adelman, S.J.

    1990-01-01

    Traditional line identification techniques result in the assignment of individual lines to an atomic or ionic species. These methods may be supplemented by wavelength coincidence statistics (WCS). The strength and weakness of these methods are discussed using spectra of a number of normal and peculiar B and A stars that have been studied independently by both methods. The present results support the overall findings of some earlier studies. WCS would be most useful in a first survey, before traditional methods have been applied. WCS can quickly make a global search for all species and in this way may enable identifications of an unexpected spectrum that could easily be omitted entirely from a traditional study. This is illustrated by O I. WCS is a subject to well known weakness of any statistical technique, for example, a predictable number of spurious results are to be expected. The danger of small number statistics are illustrated. WCS is at its best relative to traditional methods in finding a line-rich atomic species that is only weakly present in a complicated stellar spectrum

  10. Highly parallel line-based image coding for many cores.

    Science.gov (United States)

    Peng, Xiulian; Xu, Jizheng; Zhou, You; Wu, Feng

    2012-01-01

    Computers are developing along with a new trend from the dual-core and quad-core processors to ones with tens or even hundreds of cores. Multimedia, as one of the most important applications in computers, has an urgent need to design parallel coding algorithms for compression. Taking intraframe/image coding as a start point, this paper proposes a pure line-by-line coding scheme (LBLC) to meet the need. In LBLC, an input image is processed line by line sequentially, and each line is divided into small fixed-length segments. The compression of all segments from prediction to entropy coding is completely independent and concurrent at many cores. Results on a general-purpose computer show that our scheme can get a 13.9 times speedup with 15 cores at the encoder and a 10.3 times speedup at the decoder. Ideally, such near-linear speeding relation with the number of cores can be kept for more than 100 cores. In addition to the high parallelism, the proposed scheme can perform comparatively or even better than the H.264 high profile above middle bit rates. At near-lossless coding, it outperforms H.264 more than 10 dB. At lossless coding, up to 14% bit-rate reduction is observed compared with H.264 lossless coding at the high 4:4:4 profile.

  11. Cohort Profile : LifeLines, a three-generation cohort study and biobank

    NARCIS (Netherlands)

    Scholtens, Salome; Smidt, Nynke; Swertz, Morris A.; Bakker, Stephan J. L.; Dotinga, Aafje; Vonk, Judith M.; van Dijk, Freerk; van Zon, Sander K. R.; Wijmenga, Cisca; Wolffenbuttel, Bruce H. R.; Stolk, Ronald P.

    The LifeLines Cohort Study is a large population-based cohort study and biobank that was established as a resource for research on complex interactions between environmental, phenotypic and genomic factors in the development of chronic diseases and healthy ageing. Between 2006 and 2013, inhabitants

  12. Poverty Lines Based on Fuzzy Sets Theory and Its Application to Malaysian Data

    Science.gov (United States)

    Abdullah, Lazim

    2011-01-01

    Defining the poverty line has been acknowledged as being highly variable by the majority of published literature. Despite long discussions and successes, poverty line has a number of problems due to its arbitrary nature. This paper proposes three measurements of poverty lines using membership functions based on fuzzy set theory. The three…

  13. Measurement-Based Transmission Line Parameter Estimation with Adaptive Data Selection Scheme

    DEFF Research Database (Denmark)

    Li, Changgang; Zhang, Yaping; Zhang, Hengxu

    2017-01-01

    Accurate parameters of transmission lines are critical for power system operation and control decision making. Transmission line parameter estimation based on measured data is an effective way to enhance the validity of the parameters. This paper proposes a multi-point transmission line parameter...

  14. First-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer : analysis of the Italian patients enrolled in the SAiL study.

    Science.gov (United States)

    Bearz, Alessandra; Passalacqua, Rodolfo; Alabiso, Oscar; Cinieri, Saverio; Gridelli, Cesare; Cravesana, Claudia; Crinò, Lucio

    2012-11-01

    First-line bevacizumab-based therapy has been shown to improve outcomes in patients with advanced non-squamous non-small-cell lung cancer (NSCLC). The recent international phase IV SAiL study (a Study of Avastin [bevacizumab] in combination with platinum-containing chemotherapy in patients with advanced or recurrent non-squamous cell Lung cancer) evaluated the safety and efficacy of bevacizumab combined with standard chemotherapy regimens in routine clinical practice. Here we report the results of a subanalysis of baseline characteristics and efficacy data for Italian patients enrolled in SAiL. In the SAiL study, patients with untreated locally advanced, metastatic or recurrent non-squamous NSCLC received bevacizumab (7.5 or 15 mg/kg) every 3 weeks plus chemotherapy for up to six cycles, followed by single-agent bevacizumab until disease progression. Efficacy was assessed in terms of time to disease progression (TTP) and overall survival (OS). The Italian intent-to-treat population comprised 215 patients from a SAiL population of 2212 patients. At baseline, Italian patients tended to have less advanced disease than the overall population. Thus, the proportion of patients at enrollment with tumour stage IIIb and IV was 23.7 and 76.3 %, respectively, for the Italian population versus 19.7 and 80.3 % for the whole SAiL population. In addition, a higher proportion of Italian patients had an Eastern Cooperative Oncology Group performance status of 0 (72.6 vs. 37.2 %) and the prevalence of co-morbid conditions was lower in Italian patients (59.5 % of Italian patients reported a co-morbid condition and 60.0 % were receiving non-oncological treatment compared with 73.3 and 73.4 %, respectively, of SAiL patients overall). The mean exposures to bevacizumab and to chemotherapy were comparable between the Italian patient group and overall patient population, although cisplatin doublets were more commonly employed in Italian patients whereas carboplatin doublets were more

  15. Micro-simulation based analysis of railway lines robustness

    DEFF Research Database (Denmark)

    Cerreto, Fabrizio

    2015-01-01

    train course that can represent the total train delay along the line. Dispatching measures in case of disturbance are excluded by applying First-In First-Out rule in simulations. The benefits of modifications to the track infrastructure, the timetable, and the signaling system, in terms of consecutive...

  16. Base Stock Policy in a Join-Type Production Line with Advanced Demand Information

    Science.gov (United States)

    Hiraiwa, Mikihiko; Tsubouchi, Satoshi; Nakade, Koichi

    Production control such as the base stock policy, the kanban policy and the constant work-in-process policy in a serial production line has been studied by many researchers. Production lines, however, usually have fork-type, join-type or network-type figures. In addition, in most previous studies on production control, a finished product is required at the same time as arrival of demand at the system. Demand information is, however, informed before due date in practice. In this paper a join-type (assembly) production line under base stock control with advanced demand information in discrete time is analyzed. The recursive equations for the work-in-process are derived. The heuristic algorithm for finding appropriate base stock levels of all machines at short time is proposed and the effect of advanced demand information is examined by simulation with the proposed algorithm. It is shown that the inventory cost can decreases with little backlogs by using the appropriate amount of demand information and setting appropriate base stock levels.

  17. Sustainable Entrepreneurship (SE): A Revised Model Based on Triple Bottom Line (TBL)

    OpenAIRE

    Izaidin Abdul Majid; Wei-Loon Koe

    2012-01-01

    Throughout the years, researchers have suggested several fields of entrepreneurship studies, such as regular entrepreneurship, green entrepreneurship, social entrepreneurship and sustainable entrepreneurship. This literature review focused on sustainable entrepreneurship, in which a definition was proposed. Then, based upon the concept of triple bottom line, a revised model of sustainable entrepreneurship was suggested at the end of paper. The model consisted of four domains, namely economica...

  18. Problem-based learning in an on-line biotechnology course

    Science.gov (United States)

    Cheaney, James Daniel

    Problem-based learning (PBL) is a pedagogical tool that uses a "real world" problem or situation as a context for learning. PBL encourages student development of critical thinking skills, a high professional competency, problem-solving ability, knowledge acquisition, the ability to work productively as a team member and make decisions in unfamiliar situations, and the acquisition of skills that support self-directed life-long learning, metacognition, and adaptation to change. However, little research has focused on the use of PBL in on-line "virtual" classes. We conducted two studies exploring the use of PBL in an on-line biotechnology course. In the first study, ethical, legal, social, and human issues were used as a motivation for learning about DNA testing technologies, applications, and bioethical issues. In the second study, we combined PBL pedagogy with a rich multimedia environment of streaming video interviews, physical artifacts, and extensive links to articles and databases to create a multidimensional immersive PBL environment called "Robert's World". In "Robert's World", a man is determining whether to undergo a pre-symptomatic DNA test for an untreatable, incurable, fatal genetic disease for which he has a family history. In both studies, design and implementation issues of the on-line PBL environment are discussed, as are differences between on-line PBL and face-to-face PBL. Both studies provide evidence to suggest that PBL stimulates higher-order learning in students. However, in both studies, student performance on an exam testing acquisition of lower-order factual learning was lower for PBL students than for students who learned the same material through a traditional lecture-based approach. Possible reasons for this lower level of performance are explored. Student feedback expressed engagement with the issues and material covered, with reservations about some aspects of the PBL format, such as the lack of flexibility provided in cooperative

  19. Integrable microwave filter based on a photonic crystal delay line.

    Science.gov (United States)

    Sancho, Juan; Bourderionnet, Jerome; Lloret, Juan; Combrié, Sylvain; Gasulla, Ivana; Xavier, Stephane; Sales, Salvador; Colman, Pierre; Lehoucq, Gaelle; Dolfi, Daniel; Capmany, José; De Rossi, Alfredo

    2012-01-01

    The availability of a tunable delay line with a chip-size footprint is a crucial step towards the full implementation of integrated microwave photonic signal processors. Achieving a large and tunable group delay on a millimetre-sized chip is not trivial. Slow light concepts are an appropriate solution, if propagation losses are kept acceptable. Here we use a low-loss 1.5 mm-long photonic crystal waveguide to demonstrate both notch and band-pass microwave filters that can be tuned over the 0-50-GHz spectral band. The waveguide is capable of generating a controllable delay with limited signal attenuation (total insertion loss below 10 dB when the delay is below 70 ps) and degradation. Owing to the very small footprint of the delay line, a fully integrated device is feasible, also featuring more complex and elaborate filter functions.

  20. Micro-Injection Moulding In-Line Quality Assurance Based on Product and Process Fingerprints

    DEFF Research Database (Denmark)

    Baruffi, Federico; Calaon, Matteo; Tosello, Guido

    2018-01-01

    significant dimensional features of the micro part were measured using a focus variation microscope. Their dependency on the variation of µIM process parameters was studied with a Design of Experiments (DoE) statistical approach. A correlation study allowed the identification of the product fingerprint, i...... of the study showed that the dimensional quality of the micro component could be effectively controlled in-line by combining the two fingerprints, thus opening the door for future µIM in-line process optimization and quality assessment.......Micro-injection moulding (μIM) is a replication-based process enabling the cost-effective production of complex and net-shaped miniaturized plastic components. The micro-scaled size of such parts poses great challenges in assessing their dimensional quality and often leads to time...

  1. A new extraction method of loess shoulder-line based on Marr-Hildreth operator and terrain mask.

    Directory of Open Access Journals (Sweden)

    Sheng Jiang

    Full Text Available Loess shoulder-lines are significant structural lines which divide the complicated loess landform into loess interfluves and gully-slope lands. Existing extraction algorithms for shoulder-lines mainly are based on local maximum of terrain features. These algorithms are sensitive to noise for complicated loess surface and the extraction parameters are difficult to be determined, making the extraction results usually inaccurate. This paper presents a new extraction approach for loess shoulder-lines, in which Marr-Hildreth edge operator is employed to construct initial shoulder-lines. Then the terrain mask for confining the boundary of shoulder-lines is proposed based on slope degree classification and morphology methods, avoiding interference from non-valley area and modify the initial loess shoulder-lines. A case study is conducted in Yijun located in the northern Shanxi Loess Plateau of China. The Digital Elevation Models with a grid size of 5 m is applied as original data. To obtain optimal scale parameters, the Euclidean Distance Offset Percentages between shoulder-lines is calculated by the Marr-Hildreth operator and the manual delineations. The experimental results show that the new method could achieve the highest extraction accuracy when σ = 5 in Gaussian smoothing. According to the accuracy assessment, the average extraction accuracy is about 88.5%, which indicates that the proposed method is applicable for the extraction of loess shoulder-lines in the loess hilly and gully areas.

  2. High voltage transmission lines studies with the use of artificial intelligence

    Energy Technology Data Exchange (ETDEWEB)

    Ekonomou, L. [A.S.PE.T.E. - School of Pedagogical and Technological Education, Department of Electrical Engineering Educators, N. Heraklion, 141 21 Athens (Greece)

    2009-12-15

    The paper presents an alternative approach for the studies of high voltage transmission lines based on artificial intelligence and more specifically artificial neural networks (ANNs). In contrast to the existing conventional-analytical techniques and simulations which are using in the calculations empirical and/or approximating equations, this approach is based only on actual field data and actual measurements. The proposed approach is applied on high voltage transmission lines in order to calculate the lightning outages, on grounding systems in order to assess the grounding resistance and on high voltage transmission lines' polluted insulators in order to estimate the critical flashover voltage. The obtained results are very close to the actual ones for all three case studies, something which clearly implies that the ANN approach is well working and has an acceptable accuracy, constituting an additional tool of electric engineers. (author)

  3. Frequency domain based LS channel estimation in OFDM based Power line communications

    OpenAIRE

    Bogdanović, Mario

    2015-01-01

    This paper is focused on low voltage power line communication (PLC) realization with an emphasis on channel estimation techniques. The Orthogonal Frequency Division Multiplexing (OFDM) scheme is preferred technology in PLC systems because of its effective combat with frequency selective fading properties of PLC channel. As the channel estimation is one of the crucial problems in OFDM based PLC system because of a problematic area of PLC signal attenuation and interference, the improved LS est...

  4. Scenario for concurrent conceptual assembly line design: A case study

    Science.gov (United States)

    Mas, F.; Ríos, J.; Menéndez, J. L.

    2012-04-01

    The decision to design and build a new aircraft is preceded by years of research and study. Different disciplines work together throughout the lifecycle to ensure not only a complete functional definition of the product, but also a complete industrialization, a marketing plan, a maintenance plan, etc. This case study focuses on the conceptual design phase. During this phase, the design solutions that will meet the functional and industrial requirements are defined, i.e.: the basic requirements of industrialization. During this phase, several alternatives are studied, and the most attractive in terms of performance and cost requirements is selected. As a result of the study of these alternatives, it is possible to define an early conceptual design of the assembly line and its basic parameters. The plant needs, long cycle jigs & tools or industrial means and human resources with the necessary skills can be determined in advance.

  5. Chemical Degradation of Cathode Linings in Hall-Héroult Cells—An Autopsy Study of Three Spent Pot Linings

    Science.gov (United States)

    Tschöpe, Kati; Schøning, Cristian; Rutlin, Jørn; Grande, Tor

    2012-04-01

    Cathode autopsies are used frequently in the aluminum industry to investigate pot failure and the degradation of the cathode lining. The materials observed in spent pot lining (SPL) has so far been assumed to reflect the sequence of layers from the cathode to the nonreacted refractory lining as present during the operation of the cell. Here, we demonstrate that the thermal gradient in the lining is reversed during cooling and that the physical appearance of the SPL is caused both by processes taking place during operation and cooling of the shutdown cell. X-ray diffraction and microscopy of the SPL from three shutdown cells revealed that sodium metal is the main component responsible for the chemical degradation of the refractory lining. Two distinct reaction fronts were identified in the three SPL showing that sodium is penetrating deeper down into the lining than the molten fluorides from the electrolyte. The mechanisms for the transport of sodium and bath components in the refractory lining are proposed based on the experimental observations. The sodium penetration is inhibited by the formation of a viscous barrier as suggested previously, but the current findings suggest that the barrier retards diffusion of O2- and F- anions rather than Na+ as proposed previously.

  6. Document localization algorithms based on feature points and straight lines

    Science.gov (United States)

    Skoryukina, Natalya; Shemiakina, Julia; Arlazarov, Vladimir L.; Faradjev, Igor

    2018-04-01

    The important part of the system of a planar rectangular object analysis is the localization: the estimation of projective transform from template image of an object to its photograph. The system also includes such subsystems as the selection and recognition of text fields, the usage of contexts etc. In this paper three localization algorithms are described. All algorithms use feature points and two of them also analyze near-horizontal and near- vertical lines on the photograph. The algorithms and their combinations are tested on a dataset of real document photographs. Also the method of localization quality estimation is proposed that allows configuring the localization subsystem independently of the other subsystems quality.

  7. Study of Parameters that Determine Railway Line Capacity

    Directory of Open Access Journals (Sweden)

    Josip Kukec

    2005-07-01

    Full Text Available In this work the study focuses on:- determining the elements required to determine the locationfor the installation of the main signals,- calculated block lengths, and- calculations of optimal head ways, that have not been studiedin detail although they deserve special attention due totheir impact.Generally speaking, the signals are installed in compliancewith the local circumstances, i. e. according to the technicaland technological characteristics and conditions determinedby the traffic places of work they protect.The distribution and length of the blocks depend on: therailway line and its exploitation characteristics, structure andtype of trains that run on the railway line, traffic organisationand signalisation system, as well as technical and exploitationcharacte1istics of the traction vehicles and the rolling stock.What has to be considered is that the minimum section lengthcannot be shorter than the length of the braking distance, i. e.the length of the longest train which runs on the respective railwayline.The study of these parameters is supplemented by the calculationof the reduction in throughput capacity depending on thelack of uniformity in the operation of trains, which, in order tomaintain the design quality of the transportation se1vice, and inthe activities of establishing and implementing the business policyshouldn't be left out nor bypassed.

  8. Predicting for activity of second-line trastuzumab-based therapy in her2-positive advanced breast cancer

    Directory of Open Access Journals (Sweden)

    Rottenfusser Andrea

    2009-10-01

    Full Text Available Abstract Background In Her2-positive advanced breast cancer, the upfront use of trastuzumab is well established. Upon progression on first-line therapy, patients may be switched to lapatinib. Others however remain candidates for continued antibody treatment (treatment beyond progression. Here, we aimed to identify factors predicting for activity of second-line trastuzumab-based therapy. Methods Ninety-seven patients treated with > 1 line of trastuzumab-containing therapy were available for this analysis. Her2-status was determined by immunohistochemistry and re-analyzed by FISH if a score of 2+ was gained. Time to progression (TTP on second-line therapy was defined as primary study endpoint. TTP and overall survival (OS were estimated using the Kaplan-Meier product limit method. Multivariate analyses (Cox proportional hazards model, multinomial logistic regression were applied in order to identify factors associated with TTP, response, OS, and incidence of brain metastases. p values Results Median TTP on second-line trastuzumab-based therapy was 7 months (95% CI 5.74-8.26, and 8 months (95% CI 6.25-9.74 on first-line, respectively (n.s.. In the multivariate models, none of the clinical or histopthological features could reliably predict for activity of second-line trastuzumab-based treatment. OS was 43 months suggesting improved survival in patients treated with trastuzumab in multiple-lines. A significant deterioration of cardiac function was observed in three patients; 40.2% developed brain metastases while on second-line trastuzumab or thereafter. Conclusion Trastuzumab beyond progression showed considerable activity. None of the variables investigated correlated with activity of second-line therapy. In order to predict for activity of second-line trastuzumab, it appears necessary to evaluate factors known to confer trastuzumab-resistance.

  9. Simulation Study of a Vehicle Production Line for Productivity Improvement

    Directory of Open Access Journals (Sweden)

    M.F.F. Ab Rashid

    2015-06-01

    Full Text Available This paper presents the study of a motorcycle frame production line in a particular company in Malaysia. Due to the high demand, the company needs to increase its production by at least 12% compared with current output. In order to improve productivity, the production-floor data was collected and simulated using the discrete event simulation approach. Later, a number of suggestions for improvement were simulated to identify the effect of the suggestions on productivity. In addition, cost analysis was also undertaken to identify the profit margin for a particular period of time for each suggestion. Simulation results indicate that there are three suggestions that are able to fulfill the 12% volume increment. In the short term, the suggestion to hire an assistant line leader will give instant effect to the profit. Meanwhile, for the medium term, Poka-yoke will give higher profit compared with the others, while in the long term, SOP (standard operating procedure implementation will yield a better profit margin. In future, the simulation of a dynamic demand model for this product is suggested to cope with new trends in the market.

  10. AREVA main steam line break fully coupled methodology based on CATHARE-ARTEMIS - 15496

    International Nuclear Information System (INIS)

    Denis, L.; Jasserand, L.; Tomatis, D.; Segond, M.; Royere, C.; Sauvage, J.Y.

    2015-01-01

    The CATHARE code developed since 1979 by AREVA, CEA, EDF and IRSN is one of the major thermal-hydraulic system codes worldwide. In order to have at disposal realistic methodologies based on CATHARE for the whole transient and accident analysis in Chapter 15 of Safety Reports, a coupling with the code ARTEMIS was developed. ARTEMIS is the core code in AREVA's new reactor simulator system ARCADIA, using COBRA-FLX to model the thermal-hydraulics in the core. The Fully Coupled Methodology was adapted to the CATHARE-ARTEMIS coupling to perform Main Steam Line Break studies. This methodology, originally applied to the MANTA-SMART-FLICA coupling, is dedicated to Main Steam Line Break transients at zero power. The aim of this paper is to present the coupling between CATHARE and ARTEMIS and the application of the Fully Coupled Methodology in a different code environment. (authors)

  11. How To Design A Triple Bottom Line Organization: A Start-Up Case Study

    Directory of Open Access Journals (Sweden)

    Bernhard Schroeder

    2014-05-01

    Full Text Available In today’s business environment, where success for a start-up company is measured by early revenue and profit, it can be quite challenging to design a triple bottom line organization (people/planet/profit from the very beginning. We present a case study of a U.S.-based start-up firm and discuss its early challenges, developmental processes, and current success as a triple bottom line firm. The company’s founder and CEO, with no initial product, distribution, or revenue strategy, sought to develop a company that could provide the marketplace with a valuable product while also staying true to a corporate vision of positively affecting less fortunate people. Our analysis of the case suggests that the founder’s vision, passion, transparent communication, and leveraging of partners’ resources were key elements in building the firm. We draw implications of our case study for the designers of future triple bottom line organizations.

  12. A Novel Assembly Line Scheduling Algorithm Based on CE-PSO

    Directory of Open Access Journals (Sweden)

    Xiaomei Hu

    2015-01-01

    Full Text Available With the widespread application of assembly line in enterprises, assembly line scheduling is an important problem in the production since it directly affects the productivity of the whole manufacturing system. The mathematical model of assembly line scheduling problem is put forward and key data are confirmed. A double objective optimization model based on equipment utilization and delivery time loss is built, and optimization solution strategy is described. Based on the idea of solution strategy, assembly line scheduling algorithm based on CE-PSO is proposed to overcome the shortcomings of the standard PSO. Through the simulation experiments of two examples, the validity of the assembly line scheduling algorithm based on CE-PSO is proved.

  13. Study on Tower Models for EHV Transmission Line

    Directory of Open Access Journals (Sweden)

    Xu Bao-Qing

    2016-01-01

    Full Text Available Lightning outage accident is one of the main factors that threat seriously the safe and reliable operation of power system. So it is very important to establish reasonable transmission tower model and evaluate the impulse response characteristic of lightning wave traveling on the transmission tower properly for determining reliable lightning protection performance. With the help of Electromagnetic Transient Program (EMTP, six 500kV tower models are built. Aiming at one line to one transformer operating mode of 500kV substation, the intruding wave overvoltage under different tower models is calculated. The effect of tower model on intruding overvoltage has been studied. The results show that different tower models can result in great differences to the calculation results. Hence, reasonable selection of the tower model in the calculation of back- strike intruding wave is very important.

  14. A Study of the Flow Field Surrounding Interacting Line Fires

    Directory of Open Access Journals (Sweden)

    Trevor Maynard

    2016-01-01

    Full Text Available The interaction of converging fires often leads to significant changes in fire behavior, including increased flame length, angle, and intensity. In this paper, the fluid mechanics of two adjacent line fires are studied both theoretically and experimentally. A simple potential flow model is used to explain the tilting of interacting flames towards each other, which results from a momentum imbalance triggered by fire geometry. The model was validated by measuring the velocity field surrounding stationary alcohol pool fires. The flow field was seeded with high-contrast colored smoke, and the motion of smoke structures was analyzed using a cross-correlation optical flow technique. The measured velocities and flame angles are found to compare reasonably with the predicted values, and an analogy between merging fires and wind-blown flames is proposed.

  15. De novo-based transcriptome profiling of male-sterile and fertile watermelon lines.

    Science.gov (United States)

    Rhee, Sun-Ju; Kwon, Taehyung; Seo, Minseok; Jang, Yoon Jeong; Sim, Tae Yong; Cho, Seoae; Han, Sang-Wook; Lee, Gung Pyo

    2017-01-01

    The whole-genome sequence of watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai), a valuable horticultural crop worldwide, was released in 2013. Here, we compared a de novo-based approach (DBA) to a reference-based approach (RBA) using RNA-seq data, to aid in efforts to improve the annotation of the watermelon reference genome and to obtain biological insight into male-sterility in watermelon. We applied these techniques to available data from two watermelon lines: the male-sterile line DAH3615-MS and the male-fertile line DAH3615. Using DBA, we newly annotated 855 watermelon transcripts, and found gene functional clusters predicted to be related to stimulus responses, nucleic acid binding, transmembrane transport, homeostasis, and Golgi/vesicles. Among the DBA-annotated transcripts, 138 de novo-exclusive differentially-expressed genes (DEDEGs) related to male sterility were detected. Out of 33 randomly selected newly annotated transcripts and DEDEGs, 32 were validated by RT-qPCR. This study demonstrates the usefulness and reliability of the de novo transcriptome assembly in watermelon, and provides new insights for researchers exploring transcriptional blueprints with regard to the male sterility.

  16. Nonlinear estimation-based dipole source localization for artificial lateral line systems

    International Nuclear Information System (INIS)

    Abdulsadda, Ahmad T; Tan Xiaobo

    2013-01-01

    As a flow-sensing organ, the lateral line system plays an important role in various behaviors of fish. An engineering equivalent of a biological lateral line is of great interest to the navigation and control of underwater robots and vehicles. A vibrating sphere, also known as a dipole source, can emulate the rhythmic movement of fins and body appendages, and has been widely used as a stimulus in the study of biological lateral lines. Dipole source localization has also become a benchmark problem in the development of artificial lateral lines. In this paper we present two novel iterative schemes, referred to as Gauss–Newton (GN) and Newton–Raphson (NR) algorithms, for simultaneously localizing a dipole source and estimating its vibration amplitude and orientation, based on the analytical model for a dipole-generated flow field. The performance of the GN and NR methods is first confirmed with simulation results and the Cramer–Rao bound (CRB) analysis. Experiments are further conducted on an artificial lateral line prototype, consisting of six millimeter-scale ionic polymer–metal composite sensors with intra-sensor spacing optimized with CRB analysis. Consistent with simulation results, the experimental results show that both GN and NR schemes are able to simultaneously estimate the source location, vibration amplitude and orientation with comparable precision. Specifically, the maximum localization error is less than 5% of the body length (BL) when the source is within the distance of one BL. Experimental results have also shown that the proposed schemes are superior to the beamforming method, one of the most competitive approaches reported in literature, in terms of accuracy and computational efficiency. (paper)

  17. Gender-Based Analysis On-Line Dialogue. Final Report.

    Science.gov (United States)

    2001

    An online dialogue on gender-based analysis (GBA) was held from February 15 to March 7, 2001. Invitations and a background paper titled "Why Gender-Based Analysis?" were sent to 350 women's organizations and individuals throughout Canada. Efforts were made to ensure that aboriginal and Metis women, visible minority women, and women with…

  18. Registration of Urban Aerial Image and LiDAR Based on Line Vectors

    Directory of Open Access Journals (Sweden)

    Qinghong Sheng

    2017-09-01

    Full Text Available In a traditional registration of a single aerial image with airborne light detection and ranging (LiDAR data using linear features that regard line direction as a control or linear features as constraints in the solution, lacking the constraint of linear position leads to the error propagation of the adjustment model. To solve this problem, this paper presents a line vector-based registration mode (LVR in which image rays and LiDAR lines are expressed by a line vector that integrates the line direction and the line position. A registration equation of line vector is set up by coplanar imaging rays and corresponding control lines. Three types of datasets consisting of synthetic, theInternational Society for Photogrammetry and Remote Sensing (ISPRS test project, and real aerial data are used. A group of progressive experiments is undertaken to evaluate the robustness of the LVR. Experimental results demonstrate that the integrated line direction and the line position contributes a great deal to the theoretical and real accuracies of the unknowns, as well as the stability of the adjustment model. This paper provides a new suggestion that, for a single image and LiDAR data, registration in urban areas can be accomplished by accommodating rich line features.

  19. Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): a phase 4 study.

    Science.gov (United States)

    Crinò, Lucio; Dansin, Eric; Garrido, Pilar; Griesinger, Frank; Laskin, Janessa; Pavlakis, Nick; Stroiakovski, Daniel; Thatcher, Nick; Tsai, Chun-Ming; Wu, Yi-long; Zhou, Caicun

    2010-08-01

    Results of two phase 3 trials have shown first-line bevacizumab in combination with chemotherapy improves clinical outcomes in patients with advanced or recurrent non-squamous non-small-cell lung cancer (NSCLC). The SAiL (MO19390) study was undertaken to assess the safety and efficacy of first-line bevacizumab combined with standard chemotherapy regimens in clinical practice. Between August, 2006, and June, 2008, patients with untreated locally advanced, metastatic, or recurrent non-squamous NSCLC were recruited to this open-label, single group, phase 4 study from centres in 40 countries. Eligible patients had histologically or cytologically documented inoperable, locally advanced, metastatic, or recurrent disease (stage IIIB-IV); an Eastern Cooperative Oncology Group performance status of 0-2; and adequate haematological, hepatic, and renal function. Patients received bevacizumab (7.5 or 15 mg/kg every 3 weeks) plus standard chemotherapy for up to six cycles, followed by single-agent bevacizumab until disease progression. The primary endpoint was safety; analysis was by intention to treat (ITT). This study is registered with ClinicalTrials.gov, number NCT00451906. At the final data cutoff (July 24, 2009), an ITT population of 2212 patients was assessed. The incidence of clinically significant (grade > or = 3) adverse events of special interest was generally low; thromboembolism occurred in 172 (8%) patients, hypertension in 125 (6%), bleeding in 80 (4%), proteinuria in 67 (3%), and pulmonary haemorrhage in 15 (1%). 57 (3%) patients died because of these adverse events, with thromboembolism (26 patients, 1%) and bleeding (17, 1%) as the most common causes. The most common grade 3 or higher serious adverse events deemed by investigators to be associated with bevacizumab were pulmonary embolism (28 patients; 1%) and epistaxis, neutropenia, febrile neutropenia, and deep vein thrombosis (all of which occurred in 13 patients [1%]). Bevacizumab was temporarily

  20. Overlapping communities detection based on spectral analysis of line graphs

    Science.gov (United States)

    Gui, Chun; Zhang, Ruisheng; Hu, Rongjing; Huang, Guoming; Wei, Jiaxuan

    2018-05-01

    Community in networks are often overlapping where one vertex belongs to several clusters. Meanwhile, many networks show hierarchical structure such that community is recursively grouped into hierarchical organization. In order to obtain overlapping communities from a global hierarchy of vertices, a new algorithm (named SAoLG) is proposed to build the hierarchical organization along with detecting the overlap of community structure. SAoLG applies the spectral analysis into line graphs to unify the overlap and hierarchical structure of the communities. In order to avoid the limitation of absolute distance such as Euclidean distance, SAoLG employs Angular distance to compute the similarity between vertices. Furthermore, we make a micro-improvement partition density to evaluate the quality of community structure and use it to obtain the more reasonable and sensible community numbers. The proposed SAoLG algorithm achieves a balance between overlap and hierarchy by applying spectral analysis to edge community detection. The experimental results on one standard network and six real-world networks show that the SAoLG algorithm achieves higher modularity and reasonable community number values than those generated by Ahn's algorithm, the classical CPM and GN ones.

  1. Production of neutron deficient rare isotope beams at IGISOL; on-line and off-line studies

    NARCIS (Netherlands)

    Huikari, J; Dendooven, P; Jokinen, A; Nieminen, A; Penttila, H; Perajarvi, K; Popov, A; Rinta-Antila, S; Aysto, J

    This article reports on recent on-line yield measurements employing the light-ion and heavy-ion reaction-based ion guide systems and new results on a-recoil ion transport properties in ion guides with and without electric fields. In addition, the presently used ion guide designs for fusion

  2. Beyond accessibility? Toward an on-line and memory-based model of framing effects

    OpenAIRE

    Matthes, Jörg

    2007-01-01

    This theoretical article investigates the effects of media frames on individuals' judgments. In contrast to previous theorizing, we suggest that framing scholars should embrace both, on-line and memory-based judgment formation processes. Based on that premise, we propose a model that distinguishes between two phases of framing effects. Along the first phase, the media's framing contributes to the formation of an on-line or a memory-based judgment. The second phase describes six hypothetical r...

  3. Developing an EEG based On-line Closed-loop Lapse Detection and Mitigation System

    Directory of Open Access Journals (Sweden)

    Yu-Te eWang

    2014-10-01

    Full Text Available In America, sixty percent of adults reported that they have driven a motor vehicle while feeling drowsy, and at least 15-20% of fatal car accidents are fatigue-related. This study translates previous laboratory-oriented neurophysiological research to design, develop, and test an On-line Closed-loop Lapse Detection and Mitigation (OCLDM System featuring a mobile wireless dry-sensor EEG headgear and a cell-phone based real-time EEG processing platform. Eleven subjects participated in an event-related lane-keeping task, in which they were instructed to manipulate a randomly deviated, fixed-speed cruising car on a 4-lane highway. This was simulated in a 1st person view with an 8-screen and 8-projector immersive virtual-realty environment. When the subjects experienced lapses or failed to respond to events during the experiment, auditory feedback was delivered to rectify the performance decrements. However, the arousing auditory signals were not always effective. The EEG spectra exhibited statistically significant differences between effective and ineffective arousing signals, suggesting that EEG spectra could be used as a countermeasure of the efficacy of arousing signals. In this on-line pilot study, the proposed OCLDM System was able to continuously detect EEG signatures of fatigue, deliver arousing feedback to subjects suffering momentary cognitive lapses, and assess the efficacy of the feedback in near real-time to rectify cognitive lapses. The on-line testing results of the OCLDM System validated the efficacy of the arousing signals in improving subjects' response times to the subsequent lane-departure events. This study may lead to a practical on-line lapse detection and mitigation system in real-world environments.

  4. Developing an EEG-based on-line closed-loop lapse detection and mitigation system.

    Science.gov (United States)

    Wang, Yu-Te; Huang, Kuan-Chih; Wei, Chun-Shu; Huang, Teng-Yi; Ko, Li-Wei; Lin, Chin-Teng; Cheng, Chung-Kuan; Jung, Tzyy-Ping

    2014-01-01

    In America, 60% of adults reported that they have driven a motor vehicle while feeling drowsy, and at least 15-20% of fatal car accidents are fatigue-related. This study translates previous laboratory-oriented neurophysiological research to design, develop, and test an On-line Closed-loop Lapse Detection and Mitigation (OCLDM) System featuring a mobile wireless dry-sensor EEG headgear and a cell-phone based real-time EEG processing platform. Eleven subjects participated in an event-related lane-keeping task, in which they were instructed to manipulate a randomly deviated, fixed-speed cruising car on a 4-lane highway. This was simulated in a 1st person view with an 8-screen and 8-projector immersive virtual-reality environment. When the subjects experienced lapses or failed to respond to events during the experiment, auditory warning was delivered to rectify the performance decrements. However, the arousing auditory signals were not always effective. The EEG spectra exhibited statistically significant differences between effective and ineffective arousing signals, suggesting that EEG spectra could be used as a countermeasure of the efficacy of arousing signals. In this on-line pilot study, the proposed OCLDM System was able to continuously detect EEG signatures of fatigue, deliver arousing warning to subjects suffering momentary cognitive lapses, and assess the efficacy of the warning in near real-time to rectify cognitive lapses. The on-line testing results of the OCLDM System validated the efficacy of the arousing signals in improving subjects' response times to the subsequent lane-departure events. This study may lead to a practical on-line lapse detection and mitigation system in real-world environments.

  5. SLC beam line error analysis using a model-based expert system

    International Nuclear Information System (INIS)

    Lee, M.; Kleban, S.

    1988-02-01

    Commissioning particle beam line is usually a very time-consuming and labor-intensive task for accelerator physicists. To aid in commissioning, we developed a model-based expert system that identifies error-free regions, as well as localizing beam line errors. This paper will give examples of the use of our system for the SLC commissioning. 8 refs., 5 figs

  6. TVA-Based Assessment of Visual Attention Using Line-Drawings of Fruits and Vegetables

    Directory of Open Access Journals (Sweden)

    Tianlu Wang

    2018-02-01

    Full Text Available Visuospatial attention and short-term memory allow us to prioritize, select, and briefly maintain part of the visual information that reaches our senses. These cognitive abilities are quantitatively accounted for by Bundesen’s theory of visual attention (TVA; Bundesen, 1990. Previous studies have suggested that TVA-based assessments are sensitive to inter-individual differences in spatial bias, visual short-term memory capacity, top-down control, and processing speed in healthy volunteers as well as in patients with various neurological and psychiatric conditions. However, most neuropsychological assessments of attention and executive functions, including TVA-based assessment, make use of alphanumeric stimuli and/or are performed verbally, which can pose difficulties for individuals who have troubles processing letters or numbers. Here we examined the reliability of TVA-based assessments when stimuli are used that are not alphanumeric, but instead based on line-drawings of fruits and vegetables. We compared five TVA parameters quantifying the aforementioned cognitive abilities, obtained by modeling accuracy data on a whole/partial report paradigm using conventional alphabet stimuli versus the food stimuli. Significant correlations were found for all TVA parameters, indicating a high parallel-form reliability. Split-half correlations assessing internal reliability, and correlations between predicted and observed data assessing goodness-of-fit were both significant. Our results provide an indication that line-drawings of fruits and vegetables can be used for a reliable assessment of attention and short-term memory.

  7. Analysis of micro-failure behaviors in artificial muscles based on fishing line and sewing thread

    Science.gov (United States)

    Xu, J. B.; Cheng, K. F.; Tu, S. L.; He, X. M.; Ma, C.; Jin, Y. Z.; Kang, X. N.; Sun, T.; Zhang, Y.

    2017-06-01

    The aim of the present study was to discuss a new and effective method for testing artificial muscles based on micro-failure behaviors analysis. Thermo-mechanical actuators based on fishing line and sewing thread, also, the capability of responding to ambient temperature variations producing a large amount of shrinkage ratio of a resulting variation in longitudinal length. The minimum micro-failure value is 0.02μm and the maximum value is 1.72μm with nylon twist pattern. The discovery of an innovative effective testing of artificial muscles based on polymeric fibers specimens on micro-failure, rupture, slippage, etc. This research finds out a micro-failure behavior analysis of thermo-mechanical actuators based on fishing line and sewing thread. The specimens show large deformations when heated together with warping performance in terms of shrinkage of energy and densities. With the purpose of providing useful analysis data for the further technology applications, we attempt micrometre-sized artificial muscles which were also tested was readily accessible and also can be applied to other polymeric fibers. Effective use of this technique achievement relies on rotate speed, temperature and tensile direction. The results of the tensile testing experiments were outstanding with respect to some important issues related to the response of micro-structure, twisted polymeric fibers and shrinkage ratio.

  8. A METEOROLOGICAL RISK ASSESSMENT METHOD FOR POWER LINES BASED ON GIS AND MULTI-SENSOR INTEGRATION

    Directory of Open Access Journals (Sweden)

    Z. Lin

    2016-06-01

    Full Text Available Power lines, exposed in the natural environment, are vulnerable to various kinds of meteorological factors. Traditional research mainly deals with the influence of a single meteorological condition on the power line, which lacks of comprehensive effects evaluation and analysis of the multiple meteorological factors. In this paper, we use multiple meteorological monitoring data obtained by multi-sensors to implement the meteorological risk assessment and early warning of power lines. Firstly, we generate meteorological raster map from discrete meteorological monitoring data using spatial interpolation. Secondly, the expert scoring based analytic hierarchy process is used to compute the power line risk index of all kinds of meteorological conditions and establish the mathematical model of meteorological risk. By adopting this model in raster calculator of ArcGIS, we will have a raster map showing overall meteorological risks for power line. Finally, by overlaying the power line buffer layer to that raster map, we will get to know the exact risk index around a certain part of power line, which will provide significant guidance for power line risk management. In the experiment, based on five kinds of observation data gathered from meteorological stations in Guizhou Province of China, including wind, lightning, rain, ice, temperature, we carry on the meteorological risk analysis for the real power lines, and experimental results have proved the feasibility and validity of our proposed method.

  9. On-line Monitoring Device for High-voltage Switch Cabinet Partial Discharge Based on Pulse Current Method

    Science.gov (United States)

    Y Tao, S.; Zhang, X. Z.; Cai, H. W.; Li, P.; Feng, Y.; Zhang, T. C.; Li, J.; Wang, W. S.; Zhang, X. K.

    2017-12-01

    The pulse current method for partial discharge detection is generally applied in type testing and other off-line tests of electrical equipment at delivery. After intensive analysis of the present situation and existing problems of partial discharge detection in switch cabinets, this paper designed the circuit principle and signal extraction method for partial discharge on-line detection based on a high-voltage presence indicating systems (VPIS), established a high voltage switch cabinet partial discharge on-line detection circuit based on the pulse current method, developed background software integrated with real-time monitoring, judging and analyzing functions, carried out a real discharge simulation test on a real-type partial discharge defect simulation platform of a 10KV switch cabinet, and verified the sensitivity and validity of the high-voltage switch cabinet partial discharge on-line monitoring device based on the pulse current method. The study presented in this paper is of great significance for switch cabinet maintenance and theoretical study on pulse current method on-line detection, and has provided a good implementation method for partial discharge on-line monitoring devices for 10KV distribution network equipment.

  10. A continuation of base-line studies for environmentally monitoring Space Transportation Systems (STS) at John F. Kennedy Space Center. Volume 4: Threatened and endangered species of the Kennedy Space Center. Part 1: Marine turtle studies

    Science.gov (United States)

    Ehrhart, L. M.

    1980-01-01

    The status of marine turtle populations in the KSC area was studied using data from previous results from ground and aerial surveillance conducted from 1976 to April 1979. During ground surveillance, various data were recorded on emergent turtles such as: species, weight, tag number (if previously tagged), time discovered, activity at discovery and the location of discovery. Observations were also made on nesting and reproductive characteristics, population estimates, immigration and emigration and growth rate of the turtles. Mortality studies were additionally made and autopsies performed on dead turtles found in the area. It is concluded that further mortality documentation should be done just prior to and just after a future space launch operation in order to accurately assess the cause and effect relationship of such a launch on the turtle population.

  11. Study of the on line radioactive multicharged ion production

    International Nuclear Information System (INIS)

    Lecesne, N.

    1997-01-01

    This work is directly related to the SPIRAL project (Systeme de Production d'Ions Radioactifs Acceleres en Ligne) which will start at GANIL at the end of 1998. The aim of the thesis was to study the on line radioactive multicharged ion beam production stages, i.e. the production and diffusion of the radioactive nuclei in a thick target, their possible transfer up to an ECR ion source and their ionisation. Production cross sections of radioactive neutron rich nuclei, formed by fragmentation of a heavy ion beam in a thick target, were measured. An external target-ECR source system, dedicated to the radioactive noble gases production, and two internal target-ECR source systems, dedicated to the radioactive condensable element production, were built and tested on the SIRa tests bench (Separateur d'Ions Radioactifs). Different detection configurations were elaborated in order to identify the radioactive nuclei and estimate their production yields. Finally, a new method for measuring the overall efficiency of the separator was developed and allowed to study the diffusion properties of radioactive noble gases in various targets. (author)

  12. Implementations of PI-line based FBP and BPF algorithms on GPGPU

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Le [Tsinghua Univ., Beijing (China). Dept. of Engineering Physics; Xing, Yuxiang [Tsinghua Univ., Beijing (China). Dept. of Engineering Physics; Ministry of Education, Beijing (China). Key Lab. of Particle and Radiation Imaging

    2011-07-01

    Exact reconstruction is under the spotlight in cone beam CT. Katsevich put forward the first exact inversion formula for helical cone beam CT, which belongs to FBP type. Also, Pan Xiaochuan's group proposed another PI-line based exact reconstruction algorithm of BPF type. These two exact reconstruction algorithms and their derivative forms have been widely studied. In this paper, we present a different way of selecting PI-line segments appropriate for both Katsevich's FBP and Pan Xiaochuan's BPF algorithms. As 3D reconstruction contributes to massive computations and takes long time, people have made efforts to speed up the algorithms with the help of multi-core CPUs and GPGPU (General Purpose Graphics Processing Unit). In this paper, we also presents implementations for these two algorithms on GPGPU using an innovative way of selecting PI-line segments. Acceleration techniques and implementations are addressed in detail. The methods are tested on the Shepp-Logan phantom. Compared with our CPU's implementations, the accelerated algorithms on GPGPU are tens to hundreds times faster. (orig.)

  13. Risk Analysis Method Based on FMEA for Transmission Line in Lightning Hazards

    Directory of Open Access Journals (Sweden)

    You-Yuan WANG

    2014-05-01

    Full Text Available Failure rate of transmission line and reliability of power system are significantly affected by Lightning meteorological factor. In view of the complexity and variability of Lightning meteorological factors, this paper presents lightning trip-out rate model of transmission line in considering distribution of ground flash density and lightning day hours. Meanwhile, presents a failure rate model of transmission line in different condition, and a risk analysis method for transmission line considering multiple risk factors based on risk quantification. This method takes Lightning meteorological factor as the main evaluation standard, and establishes risk degree evaluation system for transmission line including another five evaluation standard. Put forward the risk indicators by quantify the risk factors based on experience date of transmission line in service. Based on the risk indexes comprehensive evaluation is conducted, and the evaluation result closer to practice is achieved, providing basis for transmission line risk warning and maintenance strategy. Through the risk analysis for 220 kV transmission line in a certain power supply bureau, the effectiveness of the proposed method is validated.

  14. Incoherent Scatter Radar Studies of Daytime Plasma Lines

    Science.gov (United States)

    Djuth, Frank T.; Carlson, Herbert C.; Zhang, Liwei D.

    2018-03-01

    First results from wideband (electron phase energies of 5-51 eV), high-resolution (0.1 eV) spectral measurements of photoelectron-enhanced plasma lines made with the 430 MHz radar at Arecibo Observatory are presented. In the F region, photoelectrons produced by solar EUV line emissions (He II and Mg IX) give rise to plasma line spectral peaks/valleys. These and other structures occur within an enhancement zone extending from electron phase energies of 14-27 eV in both the bottomside and topside ionosphere. However, photoelectron-thermal electron Coulomb energy losses can lead to a broadened spectral structure with no resolved peaks in the topside ionosphere. The plasma line energy spectra obtained in the enhancement zone exhibit a unique relation in that phase energy is dependent on pitch angle; this relation does not exist in any other part of the energy spectrum. Moreover, large fluctuations in the difference frequency between the upshifted and downshifted plasma lines are evident in the 14-27 eV energy interval. At high phase energies near 51 eV the absolute intensities of photoelectron-excited Langmuir waves are much larger than those predicted by existing theory. The new measurements call for a revision/improvement of plasma line theory in several key areas.

  15. Base line definitions and methodological lessons from Zimbabwe

    International Nuclear Information System (INIS)

    Maya, R.S.

    1995-01-01

    The UNEP Greenhouse Gas Abatement Costing Studies carried out under the management of the UNEP Collaborating Centre On Energy and Environment at Risoe National Laboratories in Denmark has placed effort in generating methodological approaches to assessing the cost of abatement activities to reduce CO 2 emissions. These efforts have produced perhaps the most comprehensive set of methodological approaches to defining and assessing the cost of greenhouse gas abatement. Perhaps the most importance aspect of the UNEP study which involved teams of researchers from ten countries is the mix of countries in which the studies were conducted and hence the representation of views and concepts from researchers in these countries particularly those from developing countries namely, Zimbabwe, India, Venezuela, Brazil, Thailand and Senegal. Methodological lessons from Zimbabwe, therefore, would have benefited from the interactions with methodological experiences form the other participating countries. Methodological lessons from the Zimbabwean study can be placed in two categories. One relates to the modelling of tools to analyze economic trends and the various factors studied in order to determine the unit cost of CO 2 abatement. The other is the definition of factors influencing the levels of emissions reducible and those realised under specific economic trends. (au)

  16. TecLines: A MATLAB-Based Toolbox for Tectonic Lineament Analysis from Satellite Images and DEMs, Part 1: Line Segment Detection and Extraction

    Directory of Open Access Journals (Sweden)

    Mehdi Rahnama

    2014-06-01

    Full Text Available Geological structures, such as faults and fractures, appear as image discontinuities or lineaments in remote sensing data. Geologic lineament mapping is a very important issue in geo-engineering, especially for construction site selection, seismic, and risk assessment, mineral exploration and hydrogeological research. Classical methods of lineaments extraction are based on semi-automated (or visual interpretation of optical data and digital elevation models. We developed a freely available Matlab based toolbox TecLines (Tectonic Lineament Analysis for locating and quantifying lineament patterns using satellite data and digital elevation models. TecLines consists of a set of functions including frequency filtering, spatial filtering, tensor voting, Hough transformation, and polynomial fitting. Due to differences in the mathematical background of the edge detection and edge linking procedure as well as the breadth of the methods, we introduce the approach in two-parts. In this first study, we present the steps that lead to edge detection. We introduce the data pre-processing using selected filters in spatial and frequency domains. We then describe the application of the tensor-voting framework to improve position and length accuracies of the detected lineaments. We demonstrate the robustness of the approach in a complex area in the northeast of Afghanistan using a panchromatic QUICKBIRD-2 image with 1-meter resolution. Finally, we compare the results of TecLines with manual lineament extraction, and other lineament extraction algorithms, as well as a published fault map of the study area.

  17. Accelerated line-by-line calculations for the radiative transfer of trace gases related to climate studies

    International Nuclear Information System (INIS)

    Clough, S.A.

    1993-01-01

    In the present study we are studying the effects of including carbon dioxide, ozone, methane, and the halocarbons in addition to water vapor in the radiating atmosphere. The study has focused on two principal issues: the effect on the spectral fluxes and cooling rates of carbon dioxide, ozone and the halocarbons at 1990 concentration levels and the change in fluxes and cooling rates as a consequence of the anticipated ten year change in the profiles of these species. For the latter study the water vapor profiles have been taken as invariant in time. The radiative line-by-line calculations using LBLRTM (Line-By-Line Radiative Transfer Model) have been performed for tropical (TRP), mid-latitude winter (MLW) and mid-latitude summer (MLS) model atmospheres. The halocarbons considered in the present study are CCl 4 , CFC-11, CFC-12 and CFC-22. In addition to considering the radiative effects of carbon dioxide at 355 ppM, the assumed current level, we have also obtained results for doubled carbon dioxide at 710 ppM. An important focus of the current research effort is the effect of the ozone depletion profile on atmospheric radiative effects

  18. An exploratory study of work-family conflicts and enrichment of front-line hotel employees in the Philippines

    OpenAIRE

    Nabong, Tristan Kirby Mansueto

    2012-01-01

    Master's thesis in International hotel and tourism management The study aims to explore and identify the front-line hotel employees’ issues and perceptions of work-life balance in the Philippine context. The respondents were front-line hotel personnel assigned to various departments of selected top luxury hotels in the Philippines. Self-administered questionnaires were used to collect the data. Factor analysis discovered five factors: (1) time-based conflict; (2) strain-based conflict; (3...

  19. Study on judgement baseline for XRF on-line detection system

    International Nuclear Information System (INIS)

    Zhang Quanshi; Bao Min

    2000-01-01

    Based on the Signal Detection Theory (SDT) and the statistics principle, the choice method of judgement baseline was studied. According to the characteristics of X-ray Fluorescence (XRF) spectra in the on-line detection system, the calculation methods for the characteristic peak of the element-tagged and background were carried out. The complex judgement baseline were rationally selected after a lot of experiments and analyzing. The operating results of near one year show that it is available

  20. Novel pulse amplifying circuits based on transmission lines of different characteristic impedance

    International Nuclear Information System (INIS)

    Belloni, F.; Doria, D.; Lorusso, A.; Nassisi, V.

    2006-01-01

    Two novel circuits used to amplify electric pulses by the coupling of transmission lines of different characteristic impedance are described. The circuits are intended for doubling voltage pulses and for doubling current pulses. The former is composed by a R 0 transmission line closed on a set of two 2R 0 storage lines connected in parallel, while the latter is composed by a R 0 transmission line closed on a set of two R 0 /2 storage lines connected in series. The length of every storage line is half of input-pulse length. In both circuits, one storage line is characterized by an open extremity and the other line by a closed extremity. Connecting opportunely the storage lines to suitable load resistors, 4R 0 and R 0 /4, for the circuit having parallel and series connected lines, respectively, a twice of the output pulse intensity is obtained. Such devices are very suitable to generate high intensity voltage and/or current peaks which are very interesting in the field of the accelerators. Both circuit behaviours have been theoretically studied and verified by computer simulations

  1. Airborne electromagnetic data levelling using principal component analysis based on flight line difference

    Science.gov (United States)

    Zhang, Qiong; Peng, Cong; Lu, Yiming; Wang, Hao; Zhu, Kaiguang

    2018-04-01

    A novel technique is developed to level airborne geophysical data using principal component analysis based on flight line difference. In the paper, flight line difference is introduced to enhance the features of levelling error for airborne electromagnetic (AEM) data and improve the correlation between pseudo tie lines. Thus we conduct levelling to the flight line difference data instead of to the original AEM data directly. Pseudo tie lines are selected distributively cross profile direction, avoiding the anomalous regions. Since the levelling errors of selective pseudo tie lines show high correlations, principal component analysis is applied to extract the local levelling errors by low-order principal components reconstruction. Furthermore, we can obtain the levelling errors of original AEM data through inverse difference after spatial interpolation. This levelling method does not need to fly tie lines and design the levelling fitting function. The effectiveness of this method is demonstrated by the levelling results of survey data, comparing with the results from tie-line levelling and flight-line correlation levelling.

  2. A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa

    Science.gov (United States)

    Otwombe, Kennedy; Lazarus, Erica; Liberty, Afaaf; Gray, Glenda E.; Greeff, Oppel B. W.; Violari, Avy

    2017-01-01

    Introduction The current World Health Organization guideline for first line antiretroviral therapy (ART) in HIV-infected children recommends the use of abacavir and lamivudine as nucleoside backbones and no longer includes stavudine. We compared treatment outcomes with abacavir (ABC) versus stavudine (d4T) in a cohort of HIV-1 infected children 6 and 12 months after antiretroviral therapy was initiated. Methods This was a retrospective case-cohort study, using programmatic data from children enrolled in the Paediatric Wellness Programme at the Perinatal HIV Research Unit in Soweto, South Africa between 2005 and 2013. Children on abacavir/stavudine who had initiated ART at age 90% for ABC and d4T were similar too (95% in ABC vs. 86% in d4T, p = 0.10). The proportion of children who died over 12 months was 3.5% in the ABC and 7.9% in the d4T group (p = 0.27). Similarly, the anthropometric measures were comparable. Conclusions It is reassuring that in the short term, in this group of patients, the treatment outcomes were similar. PMID:28686654

  3. Artificial neural network based approach to transmission lines protection

    International Nuclear Information System (INIS)

    Joorabian, M.

    1999-05-01

    The aim of this paper is to present and accurate fault detection technique for high speed distance protection using artificial neural networks. The feed-forward multi-layer neural network with the use of supervised learning and the common training rule of error back-propagation is chosen for this study. Information available locally at the relay point is passed to a neural network in order for an assessment of the fault location to be made. However in practice there is a large amount of information available, and a feature extraction process is required to reduce the dimensionality of the pattern vectors, whilst retaining important information that distinguishes the fault point. The choice of features is critical to the performance of the neural networks learning and operation. A significant feature in this paper is that an artificial neural network has been designed and tested to enhance the precision of the adaptive capabilities for distance protection

  4. Treatment Failure in HIV-Infected Children on Second-line Protease Inhibitor-Based Antiretroviral Therapy.

    Science.gov (United States)

    Suaysod, Rapeepan; Ngo-Giang-Huong, Nicole; Salvadori, Nicolas; Cressey, Tim R; Kanjanavanit, Suparat; Techakunakorn, Pornchai; Krikajornkitti, Sawitree; Srirojana, Sakulrat; Laomanit, Laddawan; Chalermpantmetagul, Suwalai; Lallemant, Marc; Le Cœur, Sophie; McIntosh, Kenneth; Traisathit, Patrinee; Jourdain, Gonzague

    2015-07-01

    Human immunodeficiency virus (HIV)-infected children failing second-line antiretroviral therapy (ART) have no access to third-line antiretroviral drugs in many resource-limited settings. It is important to identify risk factors for second-line regimen failure. HIV-infected children initiating protease inhibitor (PI)-containing second-line ART within the Program for HIV Prevention and Treatment observational cohort study in Thailand between 2002 and 2010 were included. Treatment failure was defined as confirmed HIV type 1 RNA load >400 copies/mL after at least 6 months on second-line regimen or death. Adherence was assessed by drug plasma levels and patient self-report. Cox proportional hazards regression analyses were used to identify risk factors for failure. A total of 111 children started a PI-based second-line regimen, including 59 girls (53%). Median first-line ART duration was 1.9 years (interquartile range [IQR], 1.4-3.3 years), and median age at second-line initiation was 10.7 years (IQR, 6.3-13.4 years). Fifty-four children (49%) experienced virologic failure, and 2 (2%) died. The risk of treatment failure 24 months after second-line initiation was 41%. In multivariate analyses, failure was independently associated with exposure to first-line ART for >2 years (adjusted hazard ratio [aHR], 1.8; P = .03), age >13 years (aHR, 2.9; P < .001), body mass index-for-age z score < -2 standard deviations at second-line initiation (aHR, 2.8; P = .03), and undetectable drug levels within 6 months following second-line initiation (aHR, 4.5; P < .001). Children with longer exposure to first-line ART, entry to adolescence, underweight, and/or undetectable drug levels were at higher risk of failing second-line ART and thus should be closely monitored. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  5. Qualitative study of patients’ decision-making when accepting second-line treatment after failure of first-line chemotherapy

    Science.gov (United States)

    Roch, Benoît; Roth, Caroline; Mérel, Jean-Pierre

    2018-01-01

    Objective Treatment failures in advanced lung cancer are frequent events affecting patients during or after first-line chemotherapy. International guidelines recommend second-line chemotherapy. However, around one half of patients who experience disease progression enter a systemic second-line therapy. In the herein qualitative study, we investigated patients' thoughts and attitudes determining the decision to undergo a second-line chemotherapy. Methods Thirty-three purposively selected patients who recently accepted second-line or palliative chemotherapy were invited to participate in this survey consisting of semi-structured in-depth interviews. Grounded theory was applied to investigate participants’ perceptions of the context that have surrounded their decision to undergo palliative chemotherapy. Results For most patients, tumor burden and reduced quality of life in relation with lung cancer itself were major drivers of the decision-making process. There was a balance between two different attitudes: making a decision to undergo a new line of chemotherapy or starting a psychological process in order to accept end of life. Choosing between these two attitudes allowed the patient to keep the matter of palliative care at a distance. Even in case of low chance of success, many patients who worried about their life partner's future would accept a new chemotherapy line. Some patients experienced ambivalent thoughts regarding social network, particularly about their family as daily function impairment required an increased need for relative's support. The initial "Worrying about others" thoughts left place to in an increasing self-need of care as those provided by relatives; this phenomenon might increase patients' self- perception of being a burden for others. Confidence previously established with formal caregiver support was another major decision driver: some patients with sustained confidence in their medical staff may have privileged this formal support rather

  6. Design of Control System for Flexible Packaging Bags Palletizing Production Line Based on PLC

    Science.gov (United States)

    Zheng, Huiping; Chen, Lin; Zhao, Xiaoming; Liu, Zhanyang

    Flexible packaging bags palletizing production line is to put the bags in the required area according to particular order and size, in order to finish handling, storage, loading and unloading, transportation and other logistics work of goods. Flexible packaging bags palletizing line is composed of turning bags mechanism, shaping mechanism, indexing mechanism, marshalling mechanism, pushing bags mechanism, pressing bags mechanism, laminating mechanism, elevator, tray warehouse, tray conveyor and loaded tray conveyor. Whether the whole production line can smoothly run depends on each of the above equipment and precision control among them. In this paper the technological process and the control logic of flexible packaging bags palletizing production line is introduced. Palletizing process of the production line realized automation by means of a control system based on programmable logic controller (PLC). It has the advantages of simple structure, reliable and easy maintenance etc.

  7. Discrete event model-based simulation for train movement on a single-line railway

    International Nuclear Information System (INIS)

    Xu Xiao-Ming; Li Ke-Ping; Yang Li-Xing

    2014-01-01

    The aim of this paper is to present a discrete event model-based approach to simulate train movement with the considered energy-saving factor. We conduct extensive case studies to show the dynamic characteristics of the traffic flow and demonstrate the effectiveness of the proposed approach. The simulation results indicate that the proposed discrete event model-based simulation approach is suitable for characterizing the movements of a group of trains on a single railway line with less iterations and CPU time. Additionally, some other qualitative and quantitative characteristics are investigated. In particular, because of the cumulative influence from the previous trains, the following trains should be accelerated or braked frequently to control the headway distance, leading to more energy consumption. (general)

  8. Systematic study of shell effect near drip-lines

    International Nuclear Information System (INIS)

    Adhikari, S.; Samanta, C.

    2004-01-01

    The variation of nuclear shell effects with nucleon numbers is evaluated using the modified Bethe–Weizsaecker mass formula (BWM) and the measured atomic masses. The shell effects at magic neutron numbers N=8, 20, 28, 50, 82 and 126 and magic proton numbers Z=8, 20, 28, 50 and 82 are found to vary rapidly approaching the drip-lines. The shell effect due to one magic number increases on approaching another magic number. Thus, shell effects are not always negligible near the drip-lines. (author)

  9. Ground-based observation of emission lines from the corona of a red-dwarf star.

    Science.gov (United States)

    Schmitt, J H; Wichmann, R

    2001-08-02

    All 'solar-like' stars are surrounded by coronae, which contain magnetically confined plasma at temperatures above 106 K. (Until now, only the Sun's corona could be observed in the optical-as a shimmering envelope during a total solar eclipse.) As the underlying stellar 'surfaces'-the photospheres-are much cooler, some non-radiative process must be responsible for heating the coronae. The heating mechanism is generally thought to be magnetic in origin, but is not yet understood even for the case of the Sun. Ultraviolet emission lines first led to the discovery of the enormous temperature of the Sun's corona, but thermal emission from the coronae of other stars has hitherto been detectable only from space, at X-ray wavelengths. Here we report the detection of emission from highly ionized iron (Fe XIII at 3,388.1 A) in the corona of the red-dwarf star CN Leonis, using a ground-based telescope. The X-ray flux inferred from our data is consistent with previously measured X-ray fluxes, and the non-thermal line width of 18.4 km s-1 indicates great similarities between solar and stellar coronal heating mechanisms. The accessibility and spectral resolution (45,000) of the ground-based instrument are much better than those of X-ray satellites, so a new window to the study of stellar coronae has been opened.

  10. Optimization of X-ray phase-contrast imaging based on in-line holography

    International Nuclear Information System (INIS)

    Wu Xizeng; Liu Hong; Yan Aimin

    2005-01-01

    This paper introduces a newly conceived formalism for clinical in-line phase-contrast X-ray imaging. The new formalism applies not only to ideal 'thin' objects analyzed in previous studies, but also applies to the real-world tissues used in actual clinical practice. Moreover we have identified the four clinically important factors that affect phase-contrast characteristics. These factors are: (1) body part attenuation (2) the spatial coherence of incident X-rays from an X-ray tube (3) the polychromatic nature of the X-ray source and (4) radiation dose to patients for clinical applications. Techniques of phase image-reconstruction based on the new X-ray in-line holography theory are discussed. Numerical simulations are described which were used to validate the theory. The design parameters of an optimal clinical phase-contrast mammographic imaging system which were determined based on the new theory, and validated in the simulations, are presented. The theory, image reconstruction algorithms, and numerical simulation techniques presented in this paper can be applied widely to clinical diagnostic X-ray imaging applications

  11. On-line diagnostic techniques for air-operated control valves based on time series analysis

    International Nuclear Information System (INIS)

    Ito, Kenji; Matsuoka, Yoshinori; Minamikawa, Shigeru; Komatsu, Yasuki; Satoh, Takeshi.

    1996-01-01

    The objective of this research is to study the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves - numerous valves of the type which are used in PWR plants. Generally the techniques can detect anomalies by failures in the initial stages for which detection is difficult by conventional surveillance of process parameters measured directly. However, the effectiveness of these techniques depends on the system being diagnosed. The difficulties in applying diagnostic techniques to air-operated control valves seem to come from the reduced sensitivity of their response as compared with hydraulic control systems, as well as the need to identify anomalies in low level signals that fluctuate only slightly but continuously. In this research, simulation tests were performed by setting various kinds of failure modes for a test valve with the same specifications as of a valve actually used in the plants. Actual control signals recorded from an operating plant were then used as input signals for simulation. The results of the tests confirmed the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves. (author)

  12. Registration of airborne LiDAR data and aerial images based on straight lines and POS data

    Science.gov (United States)

    Du, Quanye; Xu, Biao; Cao, Hui

    2009-10-01

    This paper presents a registration method which based on straight lines primitive. Firstly, 2D straight lines are extracted from aerial images using Canny operator and straight line fitting. In the similar way, 3D straight lines are extracted from LiDAR range images which derive from laser scanning point cloud. Secondly, 3D straight lines are projected to aerial images using collinearity equations and Position and Orientation System (POS) data. Then the corresponding lines are determined by straight line error. At last, each image's new exterior orientation elements are calculated by generalized point (straight line) photogrammetry.

  13. Spherical Projection Based Straight Line Segment Extraction for Single Station Terrestrial Laser Point Cloud

    Directory of Open Access Journals (Sweden)

    ZHANG Fan

    2015-06-01

    Full Text Available Due to the discrete distribution computing errors and lack of adaptability are ubiquitous in the current straight line extraction for TLS data methods. A 3D straight line segment extraction method is proposed based on spherical projection for single station terrestrial laser point clouds. Firstly, horizontal and vertical angles of each laser point are calculated by means of spherical coordinates, intensity panoramic image according to the two angles is generated. Secondly, edges which include straight line features are detected from intensity panoramic image by using of edge detection algorithm. Thirdly, great circles are detected from edges of panoramic image using spherical Hough transform. According to the axiom that a straight line segment in 3D space is a spherical great circle after spherical projection, detecting great circles from spherical projected data sets is essentially detecting straight line segments from 3D data sets without spherical projection. Finally, a robust 3D straight line fitting method is employed to fitting the straight lines and calculating parameters of the straight line segments. Experiments using different data sets and comparison with other methods show the accuracy and applicability of the proposed method.

  14. Radio molecular maser line study of symbiotic stars

    International Nuclear Information System (INIS)

    Cohen, N.L.; Ghigo, F.D.

    1980-01-01

    A sample of symbiotic stars has been searched for maser emission from the 1665- and 1667-MHz OH mainlines, the 22-GHz H 2 O line, and the 43-GHz SiO line. R Aqr remains the sole symbiotic for which maser emission has been detected. Its SiO spectrum reveals a pedestal of emission with a narrow superposed peak at V/sub LSR/ -26.4 +- 0.7 km/s. The line's existence and the pedestal feature are both characteristic of SiO lines found in late-type variables by Snyder et al. [Astrophys. J. 224, 512 (1978)]. For the other symbiotic stars, it is possible that conditions favorable for maser emission have been suppressed by the presence of a hot companion. Alternatively our findings may argue against the presence of late-type variables in symbiotic stars. In either case, R Aqr seems to be in a class by itself. We cannot confirm the suggestion that R Aqr is a binary, since the spectral feature has not shifted noticeably in the two years since the observations by Lepine, LeSqueren, and Scalise [Astrophys. J. 225, 869 (1978)]. However, we point out that monitoring the pedestal emission over a number of years is the least ambiguous way to discern any velocity shift that might result from orbital motion

  15. Comparing On-Line to In-Person Course Delivery: An Empirical Study

    OpenAIRE

    Jammie Price; Leslie Hossfeld

    2007-01-01

    Web-based technologies have been used in the classroom for over 15 years, including websites, email, listserves, library reserves, and text books. Among these options, social scientists range widely in their web usage – from simply posting syllabi on-line to delivering a course fully on-line in asynchronous learning networks. Use of web-based technology for instructional purposes is increasing, as is enrollment in distance education courses and on-line course offerings. Many administrators ...

  16. 'Ogura'-based 'CMS' lines with different nuclear backgrounds of cabbage revealed substantial diversity at morphological and molecular levels.

    Science.gov (United States)

    Parkash, Chander; Kumar, Sandeep; Singh, Rajender; Kumar, Ajay; Kumar, Satish; Dey, Shyam Sundar; Bhatia, Reeta; Kumar, Raj

    2018-01-01

    A comprehensive study on characterization and genetic diversity analysis was carried out in 16 'Ogura'-based 'CMS' lines of cabbage using 14 agro-morphological traits and 29 SSR markers. Agro-morphological characterization depicted considerable variations for different horticultural traits studied. The genotype, ZHA-2, performed better for most of the economically important quantitative traits. Further, gross head weight (0.76), head length (0.60) and head width (0.83) revealed significant positive correlation with net head weight. Dendrogram based on 10 quantitative traits exhibited considerable diversity among different CMS lines and principle component analysis (PCA) indicated that net and gross head weight, and head length and width are the main components of divergence between 16 CMS lines of cabbage. In molecular study, a total of 58 alleles were amplified by 29 SSR primers, averaging to 2.0 alleles in each locus. High mean values of Shannon's Information index (0.62), expected (0.45) and observed (0.32) heterozygosity and polymorphic information content (0.35) depicted substantial polymorphism. Dendrogram based on Jaccard's similarity coefficient constructed two major groups and eight sub-groups, which revealed substantial diversity among different CMS lines. In overall, based on agro-morphological and molecular studies genotype RRMA, ZHA-2 and RCA were found most divergent. Hence, they have immense potential in future breeding programs for the high-yielding hybrid development in cabbage.

  17. AUTOMATIC GLOBAL REGISTRATION BETWEEN AIRBORNE LIDAR DATA AND REMOTE SENSING IMAGE BASED ON STRAIGHT LINE FEATURES

    Directory of Open Access Journals (Sweden)

    Z. Q. Liu

    2018-04-01

    Full Text Available An automatic global registration approach for point clouds and remote sensing image based on straight line features is proposed which is insensitive to rotational and scale transformation. First, the building ridge lines and contour lines in point clouds are automatically detected as registration primitives by integrating region growth and topology identification. Second, the collinear condition equation is selected as registration transformation function which is based on rotation matrix described by unit quaternion. The similarity measure is established according to the distance between the corresponding straight line features from point clouds and the image in the same reference coordinate system. Finally, an iterative Hough transform is adopted to simultaneously estimate the parameters and obtain correspondence between registration primitives. Experimental results prove the proposed method is valid and the spectral information is useful for the following classification processing.

  18. Broadband Impedance Transformer Based on Asymmetric Coupled Transmission Lines in Nonhomogeneous Medium

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Krozer, Viktor; Meincke, Peter

    2007-01-01

    A new broadband quarter-wavelength impedance transformer based on an asymmetric coupled line section is presented. The bandwidth of the coupled line transformer is extended with the help of an interconnecting transmission line. An analytical model for the transformer is developed. The analysis...... of the structure reveals that a fractional bandwidth of more than 100% at –20 dB reflection level can be achieved with such a structure. An experimental transformer circuit has been designed, fabricated and tested. Theoretical and experimental results are fair agreement and confirm the established theory...

  19. Multi-National Banknote Classification Based on Visible-light Line Sensor and Convolutional Neural Network.

    Science.gov (United States)

    Pham, Tuyen Danh; Lee, Dong Eun; Park, Kang Ryoung

    2017-07-08

    Automatic recognition of banknotes is applied in payment facilities, such as automated teller machines (ATMs) and banknote counters. Besides the popular approaches that focus on studying the methods applied to various individual types of currencies, there have been studies conducted on simultaneous classification of banknotes from multiple countries. However, their methods were conducted with limited numbers of banknote images, national currencies, and denominations. To address this issue, we propose a multi-national banknote classification method based on visible-light banknote images captured by a one-dimensional line sensor and classified by a convolutional neural network (CNN) considering the size information of each denomination. Experiments conducted on the combined banknote image database of six countries with 62 denominations gave a classification accuracy of 100%, and results show that our proposed algorithm outperforms previous methods.

  20. Muon Beam Studies in the H4 beam line and the Gamma Irradiation Facility (GIF++)

    CERN Document Server

    Margraf, Rachel; CERN. Geneva. ATS Department

    2018-01-01

    In this note, we present detailed simulation results for the trajectory of a muon beam, traversing beam zones PPE-134 and PPE-154, produced by a 150 GeV positive hadron beam incident on collimators 9 & 10 in the H4 beam line when these collimators are placed off-beam axis to stop all hadrons and electrons. Using G4Beamline, a GEANT-4 based Monte-Carlo program, the trajectory of the muon beam has been studied for several field strengths of the GOLIATH magnet, as well as for different polarities. The position of the beam at the Gamma Irradiation Facility (GIF++), located downstream the PPE-144 area, is also presented. In addition, two configurations of the two XTDV’s present in the line (XTDV.022.520 and XTDV.022.610) have been studied, with the purpose to simulate the pion contamination of the beam both in PPE134 and GIF++.

  1. PSPICE simulation of bipolar pulse converter based on short-circuited coaxial transmission line

    International Nuclear Information System (INIS)

    Shi Lei; Fan Yajun

    2010-01-01

    The operating principle of the bipolar pulse converter based on short-circuited coaxial transmission line type is given. The output bipolar pulses are simulated by using PSPICE program on condition of different electric length and different impedance of the short-circuited coaxial transmission line. The bipolar pulses are generated by using unipolar pulse with pulse width of 2 ns in experiment, the experimental result fit well with the simulation result. (authors)

  2. Alternating current line-filter based on electrochemical capacitor utilizing template-patterned graphene

    OpenAIRE

    Zhenkun Wu; Liyi Li; Ziyin Lin; Bo Song; Zhuo Li; Kyoung-Sik Moon; Ching-Ping Wong; Shu-Lin Bai

    2015-01-01

    Aluminum electrolytic capacitors (AECs) are widely used for alternating current (ac) line-filtering. However, their bulky size is becoming more and more incompatible with the rapid development of portable electronics. Here we report a scalable process to fabricate miniaturized graphene-based ac line-filters on flexible substrates at room temperature. In this work, graphene oxide (GO) is reduced by patterned metal interdigits at room temperature and used directly as the electrode material. The...

  3. SPHERE DAQ and off-line systems: implementation based on the qdpb system

    International Nuclear Information System (INIS)

    Isupov, A.Yu.

    2003-01-01

    Design of the on-line data acquisition (DAQ) system for the SPHERE setup (LHE, JINR) is described. SPHERE DAQ is based on the qdpb (Data Processing with Branchpoints) system and configurable experimental data and CAMAC hardware representations. Implementation of the DAQ and off-line program code, depending on the SPHERE setup's hardware layout and experimental data contents, is explained as well as software modules specific for such implementation

  4. Array-based genotyping and genetic dissimilarity analysis of a set of maize inbred lines belonging to different heterotic groups

    Directory of Open Access Journals (Sweden)

    Jambrović Antun

    2014-01-01

    Full Text Available Here we describe the results of the detailed array-based genotyping obtained by using the Illumina MaizeSNP50 BeadChip of eleven inbred lines belonging to different heterotic groups relevant for maize breeding in Southeast Europe - European Corn Belt. The objectives of this study were to assess the utility of the MaizeSNP50 BeadChip platform by determining its descriptive power and to assess genetic dissimilarity of the inbred lines. The distribution of the SNPs was found not completely uniform among chromosomes, but average call rate was very high (97.9% and number of polymorphic loci was 33200 out of 50074 SNPs with known mapping position indicating descriptive power of the MaizeSNP50 BeadChip. The dendrogram obtained from UPGMA cluster analysis as well as principal component analysis (PCA confirmed pedigree information, undoubtedly distinguishing lines according to their background in two population varieties of Reid Yellow Dent and Lancaster Sure Crop. Dissimilarity analysis showed that all of the inbred lines could be distinguished from each other. Whereas cluster analysis did not definitely differentiate Mo17 and Ohio inbred lines, PCA revealed clear genetic differences between them. The studied inbred lines were confirmed to be genetically diverse, representing a large proportion of the genetic variation occurring in two maize heterotic groups.

  5. Reengineering a PC-based System into the Mobile Device Product Line

    DEFF Research Database (Denmark)

    Zhang, Weishan; Jarzabek, Stanislaw; Loughran, Neil

    2003-01-01

    There is a growing demand to port existing PC-based software systems to mobile device platforms. Systems running on mobile devices share basic characteristics with their PC-based counterparts, but differ from them in details of user interfaces, application models, etc. Systems running on mobile...... devices must also perform well using less memory than PC-based systems. Mobile devices themselves are different from each other in many ways, too. We describe how we made an existing PC-based City Guide System available on a wide range of mobile devices, in a cost-effective way. We applied "reengineering...... into a product line architecture" approach to achieve the goal. Our product line architecture facilitates reuse via generation. We generate specific City Guide Systems for target platforms including PC, Pocket PC and other mobile devices, from generic meta-components that form the City Guide System product line...

  6. Microscope self-calibration based on micro laser line imaging and soft computing algorithms

    Science.gov (United States)

    Apolinar Muñoz Rodríguez, J.

    2018-06-01

    A technique to perform microscope self-calibration via micro laser line and soft computing algorithms is presented. In this technique, the microscope vision parameters are computed by means of soft computing algorithms based on laser line projection. To implement the self-calibration, a microscope vision system is constructed by means of a CCD camera and a 38 μm laser line. From this arrangement, the microscope vision parameters are represented via Bezier approximation networks, which are accomplished through the laser line position. In this procedure, a genetic algorithm determines the microscope vision parameters by means of laser line imaging. Also, the approximation networks compute the three-dimensional vision by means of the laser line position. Additionally, the soft computing algorithms re-calibrate the vision parameters when the microscope vision system is modified during the vision task. The proposed self-calibration improves accuracy of the traditional microscope calibration, which is accomplished via external references to the microscope system. The capability of the self-calibration based on soft computing algorithms is determined by means of the calibration accuracy and the micro-scale measurement error. This contribution is corroborated by an evaluation based on the accuracy of the traditional microscope calibration.

  7. Case Study: Polycystic Livers in a Transgenic Mouse Line

    Energy Technology Data Exchange (ETDEWEB)

    Lovaglio, Jamie A.; Artwohl, James E.; Ward, Christopher J.; Diekwisch, Thomas G. H.; Ito, Yoshihiro; Fortman, Jeffrey D.

    2014-04-01

    Three mice (2 male, 1 female; age, 5 to 16 mo) from a mouse line transgenic for keratin 14 (K14)-driven LacZ expression and on an outbred Crl:CD1(ICR) background, were identified as having distended abdomens and livers that were diffusely enlarged by numerous cysts (diameter, 0.1 to 2.0 cm). Histopathology revealed hepatic cysts lined by biliary type epithelium and mild chronic inflammation, and confirmed the absence of parasites. Among 21 related mice, 5 additional affected mice were identified via laparotomy. Breeding of these 5 mice (after 5 mo of age) did not result in any offspring; the K14 mice with olycystic livers failed to reproduce. Affected male mice had degenerative testicular lesions, and their sperm was immotile. Nonpolycystic K14 control male mice bred well, had no testicular lesions, and had appropriate sperm motility. Genetic analysis did not identify an association of this phenotype with the transgene or insertion site.

  8. R and D study on on-line criticality surveillance system (V)

    International Nuclear Information System (INIS)

    Yamada, Sumasu

    2001-02-01

    In view of necessity and importance of criticality surveillance systems for ensuring the safety of nuclear fuel manufacturing and reprocessing plants, 5-year basic studies and 4 year R and D studies on an on-line criticality surveillance system were carried out since 1991. This report is a summary of these series of studies. Noticing that the signal from a neutron detector is random in principle, these series of studies aimed to accumulate knowledge for developing an inexpensive criticality surveillance system with quick response based on the Auto-Regressive Moving Average (ARMA) model identification algorithm. During five-year basic studies on criticality surveillance system since 1991, we obtained knowledge required for developing a criticality surveillance system based on the ARMA model identification algorithm through 1) studies on recursive ARMA model identification algorithms most appropriate for estimating subcriticality form time series data under a steady state condition, 2) studies on pre-processing of signal from neutron detectors, 3) developing a new recursive ARMA model identification algorithm with small time delay to estimate time-dependent subcriticality, 4) proposing a basic concept for the elements required for an on-line criticality surveillance system, and 5) numerical analysis of data from the DCA experiments. During next four-year R and D studies on a criticality surveillance system since 1996, we 1) proposed modules required for a no-line criticality surveillance system, 2) revealed effectiveness of a adaptive digital filter (ADF) algorithm, as an important redundancy to the recursive ARMA model identification algorithm to be used in the signal processing module through numerical analysis of real data, 3) proposed a module of the Feynman-α method over γ ray signal and a fast signal processing module for γ ray signal, 4) developed a line-noise removal filter(Notch filter) and revealed its effectiveness for the DCA data corrupted with power-line

  9. Resource Leveling Based on Backward Controlling Activity in Line of Balance

    Directory of Open Access Journals (Sweden)

    Lihui Zhang

    2017-01-01

    Full Text Available The line of balance method that provides continuous and uninterrupted use of resources is one of the best methods for repetitive project resource management. This paper develops a resource leveling algorithm based on the backward controlling activity in line of balance. The backward controlling activity is a kind of special activity, and if its duration is prolonged the project duration could be reduced. It brings two advantages to the resource leveling: both the resource allocated on the backward activity and the project duration are reduced. A resource leveling algorithm is presented which permits the number of crews of the backward controlling activity to be reduced until the terminal situation is reached, where the backward controlling activity does not exist or the number of crews cannot be reduced. That adjustment enables the productivity of all activities to be consistent. An illustrative pipeline project demonstrates the improvement in resource leveling. And this study designed a MATLAB program to execute the design algorithm. The proposed model could help practitioners to achieve the goals of both resource leveling and project duration reduction without increasing any resource.

  10. An atomic force microscopy-based method for line edge roughness measurement

    Energy Technology Data Exchange (ETDEWEB)

    Fouchier, M.; Pargon, E.; Bardet, B. [CNRS/UJF-Grenoble1/CEA LTM, 17 avenue des Martyrs, 38054 Grenoble cedex 9 (France)

    2013-03-14

    With the constant decrease of semiconductor device dimensions, line edge roughness (LER) becomes one of the most important sources of device variability and needs to be controlled below 2 nm for the future technological nodes of the semiconductor roadmap. LER control at the nanometer scale requires accurate measurements. We introduce a technique for LER measurement based upon the atomic force microscope (AFM). In this technique, the sample is tilted at about 45 Degree-Sign and feature sidewalls are scanned along their length with the AFM tip to obtain three-dimensional images. The small radius of curvature of the tip together with the low noise level of a laboratory AFM result in high resolution images. Half profiles and LER values on all the height of the sidewalls are extracted from the 3D images using a procedure that we developed. The influence of sample angle variations on the measurements is shown to be small. The technique is applied to the study of a full pattern transfer into a simplified gate stack. The images obtained are qualitatively consistent with cross-section scanning electron microscopy images and the average LER values agree with that obtained by critical dimension scanning electron microscopy. In addition to its high resolution, this technique presents several advantages such as the ability to image the foot of photoresist lines, complex multi-layer stacks regardless of the materials, and deep re-entrant profiles.

  11. Correlating contact line capillarity and dynamic contact angle hysteresis in surfactant-nanoparticle based complex fluids

    Science.gov (United States)

    Harikrishnan, A. R.; Dhar, Purbarun; Agnihotri, Prabhat K.; Gedupudi, Sateesh; Das, Sarit K.

    2018-04-01

    Dynamic wettability and contact angle hysteresis can be correlated to shed insight onto any solid-liquid interaction. Complex fluids are capable of altering the expected hysteresis and dynamic wetting behavior due to interfacial interactions. We report the effect of capillary number on the dynamic advancing and receding contact angles of surfactant-based nanocolloidal solutions on hydrophilic, near hydrophobic, and superhydrophobic surfaces by performing forced wetting and de-wetting experiments by employing the embedded needle method. A segregated study is performed to infer the contributing effects of the constituents and effects of particle morphology. The static contact angle hysteresis is found to be a function of particle and surfactant concentrations and greatly depends on the nature of the morphology of the particles. An order of estimate of line energy and a dynamic flow parameter called spreading factor and the transient variations of these parameters are explored which sheds light on the dynamics of contact line movement and response to perturbation of three-phase contact. The Cox-Voinov-Tanner law was found to hold for hydrophilic and a weak dependency on superhydrophobic surfaces with capillary number, and even for the complex fluids, with a varying degree of dependency for different fluids.

  12. Time Domain Analysis of Graphene Nanoribbon Interconnects Based on Transmission Line ‎Model

    Directory of Open Access Journals (Sweden)

    S. Haji Nasiri

    2012-03-01

    Full Text Available Time domain analysis of multilayer graphene nanoribbon (MLGNR interconnects, based on ‎transmission line modeling (TLM using a six-order linear parametric expression, has been ‎presented for the first time. We have studied the effects of interconnect geometry along with ‎its contact resistance on its step response and Nyquist stability. It is shown that by increasing ‎interconnects dimensions their propagation delays are increased and accordingly the system ‎becomes relatively more stable. In addition, we have compared time responses and Nyquist ‎stabilities of MLGNR and SWCNT bundle interconnects, with the same external dimensions. ‎The results show that under the same conditions, the propagation delays for MLGNR ‎interconnects are smaller than those of SWCNT bundle interconnects are. Hence, SWCNT ‎bundle interconnects are relatively more stable than their MLGNR rivals.‎

  13. Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.

    Science.gov (United States)

    Song, Jun; Leon Swisher, Christine; Im, Hyungsoon; Jeong, Sangmoo; Pathania, Divya; Iwamoto, Yoshiko; Pivovarov, Misha; Weissleder, Ralph; Lee, Hakho

    2016-04-21

    Lens-free digital in-line holography (LDIH) is a promising technology for portable, wide field-of-view imaging. Its resolution, however, is limited by the inherent pixel size of an imaging device. Here we present a new computational approach to achieve sub-pixel resolution for LDIH. The developed method is a sparsity-based reconstruction with the capability to handle the non-linear nature of LDIH. We systematically characterized the algorithm through simulation and LDIH imaging studies. The method achieved the spatial resolution down to one-third of the pixel size, while requiring only single-frame imaging without any hardware modifications. This new approach can be used as a general framework to enhance the resolution in nonlinear holographic systems.

  14. A Value-Based Business Approach to Product Line Software Engineering

    Directory of Open Access Journals (Sweden)

    Raman K. Agrawalla

    2009-08-01

    Full Text Available The present conceptual paper is an attempt to provide a Value-Based Business Approach (VBBA to product line software engineering. It argues that Product line software engineering should be seen as a system and considered as a means towards the end of appropriating more and more value for the business firm; contingent upon the fact that it provides value to customer and customer's customers operating its value creating system with agility, speed, economy and innovation; getting governed by the positive sum value creation outlook and guided by value- based management. With our value-based business triad, the product line engineering process can hope to achieve simultaneously value, variety and volume, product differentiation and cost leadership enabling the business firm to land on the virtuous value spiral.

  15. Using the Overall Line Effectiveness: A Case Study in the Wine Industry

    Directory of Open Access Journals (Sweden)

    Marcos Paulo Flamia

    2017-11-01

    Full Text Available Companies seek to continuously improve their processes in order to provide the market with competitive products. In this scenario, manufacturing plays a key role to achieve the results, and so the need arises to establish indicators to know the actual efficiency of the production process and foster this process of continuous improvement. Based on this premise, the aim of this paper is to use an analog indicator for Overall Equipment Effectiveness, the Overall Line Effectiveness, whose structure has been modified from the original indicator to identify losses not considered by the primitive indicator. The case study was conducted in a bottling line of a wine industry, and was able to show the real process efficiency and identify opportunities for improvements in this process. Research limitations and future work opportunities were highlighted.

  16. Airborne LIDAR Power Line Classification Based on Spatial Topological Structure Characteristics

    Science.gov (United States)

    Wang, Y.; Chen, Q.; Li, K.; Zheng, D.; Fang, J.

    2017-09-01

    Automatic extraction of power lines has become a topic of great importance in airborne LiDAR data processing for transmission line management. In this paper, we present a new, fully automated and versatile framework that consists of four steps: (i) power line candidate point filtering, (ii) neighbourhood selection, (iii) feature extraction based on spatial topology, and (iv) SVM classification. In a detailed evaluation involving seven neighbourhood definitions, 26 geometric features and two datasets, we demonstrated that the use of multi-scale neighbourhoods for individual 3D points significantly improved the power line classification. Additionally, we showed that the spatial topological features may even further improve the results while reducing data processing time.

  17. A Novel Fault Line Selection Method Based on Improved Oscillator System of Power Distribution Network

    Directory of Open Access Journals (Sweden)

    Xiaowei Wang

    2014-01-01

    Full Text Available A novel method of fault line selection based on IOS is presented. Firstly, the IOS is established by using math model, which adopted TZSC signal to replace built-in signal of duffing chaotic oscillator by selecting appropriate parameters. Then, each line’s TZSC decomposed by db10 wavelet packet to get CFB with the maximum energy principle, and CFB was solved by IOS. Finally, maximum chaotic distance and average chaotic distance on the phase trajectory are used to judge fault line. Simulation results show that the proposed method can accurately judge fault line and healthy line in strong noisy background. Besides, the nondetection zones of proposed method are elaborated.

  18. A new view on dam lines in Polish Arabian horses based on mtDNA analysis

    Directory of Open Access Journals (Sweden)

    Sell Jerzy

    2007-09-01

    Full Text Available Abstract Polish Arabian horses are one of the oldest and the most important Arab populations in the world. The Polish Arabian Stud Book and the Genealogical Charts by Skorkowski are the main sources of information on the ancestors of Polish Arabs. Both publications were viewed as credible sources of information until the 1990s when the data regarding one of the dam lines was questioned. The aim of the current study was to check the accuracy of the pedigree data of Polish dam lines using mtDNA analysis. The analyses of a 458 bp mtDNA D-loop fragment from representatives of 15 Polish Arabian dam lines revealed 14 distinct haplotypes. The results were inconsistent with pedigree data in the case of two lines. A detailed analysis of the historical sources was performed to explain these discrepancies. Our study revealed that representatives of different lines shared the same haplotypes. We also noted a genetic identity between some lines founded by Polish mares of unknown origin and lines established by desert-bred mares.

  19. Study on dynamic behavior analysis of towed line array sensor

    Directory of Open Access Journals (Sweden)

    Hyun Kyoung Shin

    2012-03-01

    Full Text Available A set of equations of motion is derived for vibratory motions of an underwater cable connected to a moving vehicle at one end and with drogues at the other end. From the static analysis, cable configurations are obtained for different vehicle speeds and towing pretensions are determined by fluid resistance of drogues. Also the dynamic analysis is required to predict its vibratory motion. Nonlinear fluid drag forces greatly influence the dynamic tension. In this study, a numerical analysis program was developed to find out the characteristic of cable behaviour. The motion is described in terms of space and time coordinates based on Chebyshev polynomial expansions. For the spatial integration the collocation method is employed and the Newmark method is applied for the time integration. Dynamic tensions, displacements, velocities, accelerations were predicted in the time domain while natural frequencies and transfer functions were obtained in the frequency domain.

  20. A Low Cost 3D Acquiring System for Mushroom Robot Based on Webcam and Line Laser

    Directory of Open Access Journals (Sweden)

    Gang Sun

    2014-03-01

    Full Text Available This paper presents a low cost 3D acquiring system for mushroom robot based on webcam and line laser. The system comprises Webcam, semiconductor line laser, motion platform and data process unit. The system can get the 3D information of the Pleurotus eryngii in bottle based on structured light scanning theory. Field test shows the accuracy of the height is less than 2mm and it can be use to locate the buds in the bottle correctly. It has the potention to fulfill the requirement of the location of the mushroom for thinning bud robot.

  1. New schemes for high-voltage pulsed generators based on stepped transmission lines

    International Nuclear Information System (INIS)

    Bossamykin, V.S.; Gordeev, V.S.; Pavlovskii, A.I.

    1993-01-01

    Wave processes were analyzed from the point of effective energy delivery in pulsed power systems based on transmission lines. A series of new schemes for the pulsed generators based on multistage stepped transmission lines both with the capacitive and inductive energy storage was found. These devices can provide voltage or current transformation up to 5-10 times due to wave processes if stage's characteristic impedances are in a certain correlation. The schemes suggested can be widely applied in the new powerful pulsed power accelerators. The theoretical conclusions are justified experimentally

  2. Size characterization of airborne SiO2 nanoparticles with on-line and off-line measurement techniques: an interlaboratory comparison study

    Science.gov (United States)

    Motzkus, C.; Macé, T.; Gaie-Levrel, F.; Ducourtieux, S.; Delvallee, A.; Dirscherl, K.; Hodoroaba, V.-D.; Popov, I.; Popov, O.; Kuselman, I.; Takahata, K.; Ehara, K.; Ausset, P.; Maillé, M.; Michielsen, N.; Bondiguel, S.; Gensdarmes, F.; Morawska, L.; Johnson, G. R.; Faghihi, E. M.; Kim, C. S.; Kim, Y. H.; Chu, M. C.; Guardado, J. A.; Salas, A.; Capannelli, G.; Costa, C.; Bostrom, T.; Jämting, Å. K.; Lawn, M. A.; Adlem, L.; Vaslin-Reimann, S.

    2013-10-01

    Results of an interlaboratory comparison on size characterization of SiO2 airborne nanoparticles using on-line and off-line measurement techniques are discussed. This study was performed in the framework of Technical Working Area (TWA) 34—"Properties of Nanoparticle Populations" of the Versailles Project on Advanced Materials and Standards (VAMAS) in the project no. 3 "Techniques for characterizing size distribution of airborne nanoparticles". Two types of nano-aerosols, consisting of (1) one population of nanoparticles with a mean diameter between 30.3 and 39.0 nm and (2) two populations of non-agglomerated nanoparticles with mean diameters between, respectively, 36.2-46.6 nm and 80.2-89.8 nm, were generated for characterization measurements. Scanning mobility particle size spectrometers (SMPS) were used for on-line measurements of size distributions of the produced nano-aerosols. Transmission electron microscopy, scanning electron microscopy, and atomic force microscopy were used as off-line measurement techniques for nanoparticles characterization. Samples were deposited on appropriate supports such as grids, filters, and mica plates by electrostatic precipitation and a filtration technique using SMPS controlled generation upstream. The results of the main size distribution parameters (mean and mode diameters), obtained from several laboratories, were compared based on metrological approaches including metrological traceability, calibration, and evaluation of the measurement uncertainty. Internationally harmonized measurement procedures for airborne SiO2 nanoparticles characterization are proposed.

  3. Size characterization of airborne SiO{sub 2} nanoparticles with on-line and off-line measurement techniques: an interlaboratory comparison study

    Energy Technology Data Exchange (ETDEWEB)

    Motzkus, C., E-mail: charles.motzkus@lne.fr; Mace, T.; Gaie-Levrel, F.; Ducourtieux, S.; Delvallee, A. [Laboratoire National de Metrologie et d' Essais (LNE) (France); Dirscherl, K. [Danish Fundamental Metrology (DFM) (Denmark); Hodoroaba, V.-D. [BAM Federal Institute for Materials Research and Testing (Germany); Popov, I. [The Hebrew University of Jerusalem, Unit for Nanocharacterization (Israel); Popov, O.; Kuselman, I. [National Physical Laboratory of Israel (INPL) (Israel); Takahata, K.; Ehara, K. [National Institute of Advanced Industrial Science and Technology (AIST), National Metrology Institute of Japan (NMIJ) (Japan); Ausset, P.; Maille, M. [Universite Paris-Est Creteil et Universite Paris-Diderot, Laboratoire Interuniversitaire des Systemes Atmospheriques (LISA), UMR CNRS 7583 (France); Michielsen, N.; Bondiguel, S.; Gensdarmes, F. [Institut de Radioprotection et de Surete Nucleaire (IRSN), PSN-RES, SCA, LPMA (France); Morawska, L.; Johnson, G. R.; Faghihi, E. M. [Queensland University of Technology (QUT), International Laboratory for Air Quality and Health (ILAQH) (Australia); and others

    2013-10-15

    Results of an interlaboratory comparison on size characterization of SiO{sub 2} airborne nanoparticles using on-line and off-line measurement techniques are discussed. This study was performed in the framework of Technical Working Area (TWA) 34-'Properties of Nanoparticle Populations' of the Versailles Project on Advanced Materials and Standards (VAMAS) in the project no. 3 'Techniques for characterizing size distribution of airborne nanoparticles'. Two types of nano-aerosols, consisting of (1) one population of nanoparticles with a mean diameter between 30.3 and 39.0 nm and (2) two populations of non-agglomerated nanoparticles with mean diameters between, respectively, 36.2-46.6 nm and 80.2-89.8 nm, were generated for characterization measurements. Scanning mobility particle size spectrometers (SMPS) were used for on-line measurements of size distributions of the produced nano-aerosols. Transmission electron microscopy, scanning electron microscopy, and atomic force microscopy were used as off-line measurement techniques for nanoparticles characterization. Samples were deposited on appropriate supports such as grids, filters, and mica plates by electrostatic precipitation and a filtration technique using SMPS controlled generation upstream. The results of the main size distribution parameters (mean and mode diameters), obtained from several laboratories, were compared based on metrological approaches including metrological traceability, calibration, and evaluation of the measurement uncertainty. Internationally harmonized measurement procedures for airborne SiO{sub 2} nanoparticles characterization are proposed.

  4. Size characterization of airborne SiO2 nanoparticles with on-line and off-line measurement techniques: an interlaboratory comparison study

    International Nuclear Information System (INIS)

    Motzkus, C.; Macé, T.; Gaie-Levrel, F.; Ducourtieux, S.; Delvallee, A.; Dirscherl, K.; Hodoroaba, V.-D.; Popov, I.; Popov, O.; Kuselman, I.; Takahata, K.; Ehara, K.; Ausset, P.; Maillé, M.; Michielsen, N.; Bondiguel, S.; Gensdarmes, F.; Morawska, L.; Johnson, G. R.; Faghihi, E. M.

    2013-01-01

    Results of an interlaboratory comparison on size characterization of SiO 2 airborne nanoparticles using on-line and off-line measurement techniques are discussed. This study was performed in the framework of Technical Working Area (TWA) 34—“Properties of Nanoparticle Populations” of the Versailles Project on Advanced Materials and Standards (VAMAS) in the project no. 3 “Techniques for characterizing size distribution of airborne nanoparticles”. Two types of nano-aerosols, consisting of (1) one population of nanoparticles with a mean diameter between 30.3 and 39.0 nm and (2) two populations of non-agglomerated nanoparticles with mean diameters between, respectively, 36.2–46.6 nm and 80.2–89.8 nm, were generated for characterization measurements. Scanning mobility particle size spectrometers (SMPS) were used for on-line measurements of size distributions of the produced nano-aerosols. Transmission electron microscopy, scanning electron microscopy, and atomic force microscopy were used as off-line measurement techniques for nanoparticles characterization. Samples were deposited on appropriate supports such as grids, filters, and mica plates by electrostatic precipitation and a filtration technique using SMPS controlled generation upstream. The results of the main size distribution parameters (mean and mode diameters), obtained from several laboratories, were compared based on metrological approaches including metrological traceability, calibration, and evaluation of the measurement uncertainty. Internationally harmonized measurement procedures for airborne SiO 2 nanoparticles characterization are proposed

  5. Solar magnetic field studies using the 12 micron emission lines. I - Quiet sun time series and sunspot slices

    Science.gov (United States)

    Deming, Drake; Boyle, Robert J.; Jennings, Donald E.; Wiedemann, Gunter

    1988-01-01

    The use of the extremely Zeeman-sensitive IR emission line Mg I, at 12.32 microns, to study solar magnetic fields. Time series observations of the line in the quiet sun were obtained in order to determine the response time of the line to the five-minute oscillations. Based upon the velocity amplitude and average period measured in the line, it is concluded that it is formed in the temperature minimum region. The magnetic structure of sunspots is investigated by stepping a small field of view in linear 'slices' through the spots. The region of penumbral line formation does not show the Evershed outflow common in photospheric lines. The line intensity is a factor of two greater in sunspot penumbrae than in the photosphere, and at the limb the penumbral emission begins to depart from optical thinness, the line source function increasing with height. For a spot near disk center, the radial decrease in absolute magnetic field strength is steeper than the generally accepted dependence.

  6. Assessment of surge arrester failure rate and application studies in Hellenic high voltage transmission lines

    Energy Technology Data Exchange (ETDEWEB)

    Christodoulou, C.A.; Fotis, G.P.; Gonos, I.F.; Stathopulos, I.A. [National Technical University of Athens, School of Electrical and Computer Engineering, High Voltage Laboratory, 9 Iroon Politechniou St., Zografou Campus, 157 80 Athens (Greece); Ekonomou, L. [A.S.PE.T.E. - School of Pedagogical and Technological Education, Department of Electrical Engineering Educators, N. Heraklion, 141 21 Athens (Greece)

    2010-02-15

    The use of transmission line surge arresters to improve the lightning performance of transmission lines is becoming more common. Especially in areas with high soil resistivity and ground flash density, surge arresters constitute the most effective protection mean. In this paper a methodology for assessing the surge arrester failure rate based on the electrogeometrical model is presented. Critical currents that exceed arresters rated energy stress were estimated by the use of a simulation tool. The methodology is applied on operating Hellenic transmission lines of 150 kV. Several case studies are analyzed by installing surge arresters on different intervals, in relation to the region's tower footing resistance and the ground flash density. The obtained results are compared with real records of outage rate showing the effectiveness of the surge arresters in the reduction of the recorded failure rate. The presented methodology can be proved valuable to the studies of electric power systems designers intending in a more effective lightning protection, reducing the operational costs and providing continuity of service. (author)

  7. Research and application on imaging technology of line structure light based on confocal microscopy

    Science.gov (United States)

    Han, Wenfeng; Xiao, Zexin; Wang, Xiaofen

    2009-11-01

    In 2005, the theory of line structure light confocal microscopy was put forward firstly in China by Xingyu Gao and Zexin Xiao in the Institute of Opt-mechatronics of Guilin University of Electronic Technology. Though the lateral resolution of line confocal microscopy can only reach or approach the level of the traditional dot confocal microscopy. But compared with traditional dot confocal microscopy, it has two advantages: first, by substituting line scanning for dot scanning, plane imaging only performs one-dimensional scanning, with imaging velocity greatly improved and scanning mechanism simplified, second, transfer quantity of light is greatly improved by substituting detection hairline for detection pinhole, and low illumination CCD is used directly to collect images instead of photoelectric intensifier. In order to apply the line confocal microscopy to practical system, based on the further research on the theory of the line confocal microscopy, imaging technology of line structure light is put forward on condition of implementation of confocal microscopy. Its validity and reliability are also verified by experiments.

  8. Study of ion line broadening in the Tormac discharge

    International Nuclear Information System (INIS)

    Shaw, R.S.

    1980-07-01

    Tormac (Toroidal Magnetic Cusp) is a magnetic confinement plasma concept having absolute minimum-B geometry. Two versions of Tormac are considered here. Tormac T IV-c has a glass vessel of rectangular cross section, 0.5 m in diameter. The confinement field rises to approx. 4.5 kG in approx. 8.3 μsec. Tormac T V has a T-shaped glass vessel, 1 m in diameter, with a field of approx. 3 kG, rising in approx. 10 μsec. Gaussian HeII 4686 A spectral lines having full widths at half maximum over 2 A have been observed in both Tormac plasmas

  9. PENINGKATAN JAMINAN KUALITAS ASSEMBLY LINE (Studi Kasus di Industri Otomotif

    Directory of Open Access Journals (Sweden)

    Halim Junaidi

    2005-01-01

    Full Text Available The paper presents the improvement of quality assurance at an automotive industry which produces multi-purpose vehicle. Their multi-purpose vehicle is a global product, which means that it should concern not only domestic market demand but also international market demand and specification. Thus to maintain customer satisfaction on product quality, one of the efforts can be done to improve quality assurance level is by implementing Quality Assurance Network activity. Abstract in Bahasa Indonesia : Artikel ini membahas peningkatan jaminan kualitas assembly line di industri otomotif yang memproduksi kendaraan niaga. Kendaraan ini adalah produk yang bertaraf global, artinya kendaraan niaga yang harus mampu memenuhi bukan hanya permintaan pasar domestik melainkan juga spesifikasi dan permintaan pasar mancanegara. Oleh sebab itu untuk tetap dapat mempertahankan kepuasan konsumen terhadap kualitas produk, salah satu upaya yang dapat digunakan meningkatkan jaminan kualitas perusahaan adalah dengan mengimplementasikan aktivitas quality assurance network. Kata kunci: jaminan kualitas, aktivitas quality assurance network.

  10. The LifeLines Cohort Study : Prevalence and treatment of cardiovascular disease and risk factors

    NARCIS (Netherlands)

    van der Ende, M. Yldau; Hartman, Minke H. T.; Hagemeijer, Yanick; Meems, Laura M. G.; de Vries, Hendrik Sierd; Stolk, Ronald P.; de Boer, Rudolf A.; Sijtsma, Anna; van der Meer, Peter; Rienstra, Michiel; van der Harst, Pim

    2017-01-01

    Background: The LifeLines Cohort Study is a large three-generation prospective study and Biobank. Recruitment and data collection started in 2006 and follow-up is planned for 30 years. The central aim of LifeLines is to understand healthy ageing in the 21st century. Here, the study design, methods,

  11. Moral Stress, Moral Practice, and Ethical Climate in Community-Based Drug-Use Research: Views From the Front Line.

    Science.gov (United States)

    Fisher, Celia B; True, Gala; Alexander, Leslie; Fried, Adam L

    2013-01-01

    The role of front-line researchers, those whose responsibilities include face-to-face contact with participants, is critical to ensuring the responsible conduct of community-based drug use research. To date, there has been little empirical examination of how front-line researchers perceive the effectiveness of ethical procedures in their real-world application and the moral stress they may experience when adherence to scientific procedures appears to conflict with participant protections. This study represents a first step in applying psychological science to examine the work-related attitudes, ethics climate, and moral dilemmas experienced by a national sample of 275 front-line staff members whose responsibilities include face-to-face interaction with participants in community-based drug-use research. Using an anonymous Web-based survey we psychometrically evaluated and examined relationships among six new scales tapping moral stress (frustration in response to perceived barriers to conducting research in a morally appropriate manner); organizational ethics climate; staff support; moral practice dilemmas (perceived conflicts between scientific integrity and participant welfare); research commitment; and research mistrust. As predicted, front-line researchers who evidence a strong commitment to their role in the research process and who perceive their organizations as committed to research ethics and staff support experienced lower levels of moral stress. Front-line researchers who were distrustful of the research enterprise and frequently grappled with moral practice dilemmas reported higher levels of moral stress. Applying psychometrically reliable scales to empirically examine research ethics challenges can illuminate specific threats to scientific integrity and human subjects protections encountered by front-line staff and suggest organizational strategies for reducing moral stress and enhancing the responsible conduct of research.

  12. Line narrowing spectroscopic studies of DNA-carcinogen adducts and DNA-dye complexes

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Myungkoo [Iowa State Univ., Ames, IA (United States)

    1995-12-06

    Laser-induced fluorescence line narrowing and non-line narrowing spectroscopic methods were applied to conformational studies of stable DNA adducts of the 7β, 8α-dihydoxy-9α, l0α-epoxy-7,8,9, 10-tetrahydrobenzo[α]pyrene (anti-BPDE). Stereochemically distinct (+)-trans-, (-)-trans-, (+)-cis- and (-)-cis adducts of anti-BPDE bound to exocyclic amino group of the central guanine in an 11-mer oligonucleotide, exist in a mixture of conformations in frozen aqueous buffer matrices. The (+)-trans adduct adopts primarily an external conformation with a smaller fraction ( ~25 %) exists in a partially base-stacked conformation. Both cis adducts were found to be intercalated with significant π-π stacking interactions between the pyrenyl residues and the bases. Conformations of the trans-adduct of (+)-anti -BPDE in 11-mer oligonucleotides were studied as a function of flanking bases. In single stranded form the adduct at G2 or G3 (5 ft-flanking, base guanine) adopts a conformation with strong, interaction with the bases. In contrast, the adduct with a 5ft-flanking, thymine exists in a primarily helixexternal conformation. Similar differences were observed in the double stranded oligonucleotides. The nature of the 3ft-flanking base has little influence on the conformational equilibrium of the (+)-trans-anti BPDE-dG adduct. The formation and repair of BPDE-N2-dG in DNA isolated from the skin of mice treated topically with benzo[α]pyrene (BP) was studied. Low-temperature fluorescence spectroscopy of the intact DNA identified the major adduct as (+)-trans-anti-BPDE-N-dG, and the minor adduct fraction consisted mainly of (+)-cis-anti-BPDE-N2-dG.

  13. Line narrowing spectroscopic studies of DNA-carcinogen adducts and DNA-dye complexes

    International Nuclear Information System (INIS)

    Suh, Myungkoo.

    1995-01-01

    Laser-induced fluorescence line narrowing and non-line narrowing spectroscopic methods were applied to conformational studies of stable DNA adducts of the 7β, 8α-dihydoxy-9α, l0α-epoxy-7,8,9, 10-tetrahydrobenzo[α]pyrene (anti-BPDE). Stereochemically distinct (+)-trans-, (-)-trans-, (+)-cis- and (-)-cis adducts of anti-BPDE bound to exocyclic amino group of the central guanine in an 11-mer oligonucleotide, exist in a mixture of conformations in frozen aqueous buffer matrices. The (+)-trans adduct adopts primarily an external conformation with a smaller fraction ( ∼ 25 %) exists in a partially base-stacked conformation. Both cis adducts were found to be intercalated with significant π-π stacking interactions between the pyrenyl residues and the bases. Conformations of the trans-adduct of (+)-anti -BPDE in 11-mer oligonucleotides were studied as a function of flanking bases. In single stranded form the adduct at G 2 or G 3 (5 ft-flanking, base guanine) adopts a conformation with strong, interaction with the bases. In contrast, the adduct with a 5ft-flanking, thymine exists in a primarily helixexternal conformation. Similar differences were observed in the double stranded oligonucleotides. The nature of the 3ft-flanking base has little influence on the conformational equilibrium of the (+)-trans-anti BPDE-dG adduct. The formation and repair of BPDE-N 2 -dG in DNA isolated from the skin of mice treated topically with benzo[α]pyrene (BP) was studied. Low-temperature fluorescence spectroscopy of the intact DNA identified the major adduct as (+)-trans-anti-BPDE-N-dG, and the minor adduct fraction consisted mainly of (+)-cis-anti-BPDE-N 2 -dG

  14. Determination of Peroxide-Based Explosives Using Liquid Chromatography with On-Line Infrared Detection

    NARCIS (Netherlands)

    Schulte-Ladbeck, Rasmus; Edelmann, Andrea; Quintas, Guillermo; Lendl, Bernhard; Karst, U.

    2006-01-01

    A nondestructive analytical method for peroxide-based explosives determination in solid samples is described. Reversed-phase high-performance liquid chromatography in combination with on-line Fourier transform infrared (FT-IR) detection is used for the analysis of triacetonetriperoxide (TATP) and

  15. Optimal reconfiguration-based dynamic tariff for congestion management and line loss reduction in distribution networks

    DEFF Research Database (Denmark)

    Huang, Shaojun; Wu, Qiuwei; Cheng, Lin

    2016-01-01

    This paper presents an optimal reconfiguration-based dynamic tariff (DT) method for congestion management and line loss reduction in distribution networks with high penetration of electric vehicles. In the proposed DT concept, feeder reconfiguration (FR) is employed through mixed integer programm...

  16. A new time-digital convert circuit based on digital delay line

    International Nuclear Information System (INIS)

    Liu Haifeng; Guo Ying; Zhang Zhi

    2004-01-01

    An introduction of a new method of time-digital convert circuit based on digital delay line is given. High precision and good reliability can be realized when it is combined with traditional counting convert method in the measurement of large scale pulse width and low frequency self-excitation oscillator. (authors)

  17. Lightning current distribution to ground at a power line tower carrying a radio base station

    NARCIS (Netherlands)

    Grcev, L.; Deursen, van A.P.J.; Waes, van J.B.M.

    2005-01-01

    Radio base stations are often mounted on towers of power transmission lines. They are usually powered from the low-voltage network through an isolating transformer, to separate the high- and low-voltage networks. The isolating transformer ensures security at customers' premises in the case of nearby

  18. Theory of direct-interband-transition line shapes based on Mori's method

    International Nuclear Information System (INIS)

    Sam Nyung Yi; Jai Yon Ryu; Ok Hee Chung; Joung Young Sug; Sang Don Choi; Yeon Choon Chung

    1987-01-01

    A theory of direct interband optical transition in the electron-phonon system is introduced on the basis of the Kubo formalism and by using Mori's method of calculation. The line shape functions are introduced in two different ways and are compared with those obtained by Choi and Chung based on Argyres and Sigel's projection technique

  19. Efficacy of Levofloxacin-Based Third-Line Therapy for the Eradication of Helicobacter pylori in Peptic Ulcer Disease.

    Science.gov (United States)

    Lim, Joo Hyun; Kim, Sang Gyun; Song, Ji Hyun; Hwang, Jae Jin; Lee, Dong Ho; Han, Jae Pil; Hong, Su Jin; Kim, Ji Hyun; Jeon, Seong Woo; Kim, Gwang Ha; Shim, Ki-Nam; Shin, Woon Geon; Kim, Tae Ho; Kim, Sun Moon; Chung, Il-Kwon; Kim, Hyun-Soo; Kim, Heung Up; Lee, Joongyub; Kim, Jae Gyu

    2017-03-15

    The resistance rate of Helicobacter pylori is gradually increasing. We aimed to evaluate the efficacy of levofloxacin-based third-line H. pylori eradication in peptic ulcer disease. Between 2002 and 2014, 110 patients in 14 medical centers received levofloxacin-based third-line H. pylori eradication therapy for peptic ulcer disease. Of these, 88 were included in the study; 21 were excluded because of lack of follow-up and one was excluded for poor compliance. Their eradication rates, treatment regimens and durations, and types of peptic ulcers were analyzed. The overall eradiation rate was 71.6%. The adherence rate was 80.0%. All except one received a proton-pump inhibitor, amoxicillin, and levofloxacin. One received a proton-pump inhibitor, amoxicillin, levofloxacin, and clarithromycin, and the eradication was successful. Thirty-one were administered the therapy for 7 days, 25 for 10 days, and 32 for 14 days. No significant differences were observed in the eradication rates between the three groups (7-days, 80.6% vs 10-days, 64.0% vs 14-days, 68.8%, p=0.353). Additionally, no differences were found in the eradiation rates according to the type of peptic ulcer (gastric ulcer, 73.2% vs duodenal/gastroduodenal ulcer, 68.8%, p=0.655). Levofloxacin-based third-line H. pylori eradication showed efficacy similar to that of previously reported first/second-line therapies.

  20. TecLines: A MATLAB-Based Toolbox for Tectonic Lineament Analysis from Satellite Images and DEMs, Part 2: Line Segments Linking and Merging

    Directory of Open Access Journals (Sweden)

    Mehdi Rahnama

    2014-11-01

    Full Text Available Extraction and interpretation of tectonic lineaments is one of the routines for mapping large areas using remote sensing data. However, this is a subjective and time-consuming process. It is difficult to choose an optimal lineament extraction method in order to reduce subjectivity and obtain vectors similar to what an analyst would manually extract. The objective of this study is the implementation, evaluation and comparison of Hough transform, segment merging and polynomial fitting methods towards automated tectonic lineament mapping. For this purpose we developed a new MATLAB-based toolbox (TecLines. The proposed toolbox capabilities were validated using a synthetic Digital Elevation Model (DEM and tested along in the Andarab fault zone (Afghanistan where specific fault structures are known. In this study, we used filters in both frequency and spatial domains and the tensor voting framework to produce binary edge maps. We used the Hough transform to extract linear image discontinuities. We used B-spline as a polynomial curve fitting method to eliminate artificial line segments that are out of interest and to link discontinuous segments with similar trends. We performed statistical analyses in order to compare the final image discontinuities maps with existing references map.

  1. Study of radiosensitization of chloroquine on esophageal cancer cell line

    International Nuclear Information System (INIS)

    Yuan Xiaoli; Li Tao; Huang Jianming; Zha Xiao; Deng Bifang; Lang Jinyi

    2014-01-01

    Objective: To investigate the possibility of chloroquine radiosensitization of esophageal cancer cell line TE-1 and its further mechanism. Methods: Effect of chloroquine on cell viability of TE-1 cells was determined by MTT method. Expression of LC3, Beclin-1 and formation of acidic vesicular organelles (AVOs) were determined by Western blot, and fluorescence staining with Lyso-Tracker Red DND-99, respectively. Clonogenic survival of TE-1 cells was examined by clonogenic forming assay. Results: Chloroquine showed dose-dependent inhibition of TE-1 cell growth, and its values of IC_5_0 and IC_1_0 were (72.33±5.28) and (15.42±3.33) μmol/L, respectively. The expression of Beclin-1 and LC3-II/I markedly increased in irradiated TE-1 cells. The addition of chloroquine with IC_1_0 concentration significantly reduced the fluorescence and intensity of AVOs accumulation in the cytoplasm of TE-1 cells. Clonogenic survival fraction decreased obviously in TE-1 cells with addition of chloroquine after radiation and the value of SERD0 was 1.439. Conclusions: Chloroquine could radiosensitize esophageal cancer cells by blocking autophagy-lysosomal pathway and be used as a potential radiosensitizing strategy. (authors)

  2. Several key issues on implementing delay line based TDCs using FPGAs

    International Nuclear Information System (INIS)

    Wu, Jinyuan

    2009-01-01

    Several topics in FPGA delay line based TDCs are discussed in this document. First, FPGA specific issues such as considerations on the delay line choice in different FPGA families, Wave Union Launchers, 'bubble proof' encoding logic, etc. are examined. Next, common problems for both FPGA TDCs and ASIC TDCs such as schemes of coarse time counter implementation, bin-by-bin calibration and noise issues due to single ended signals are discussed. Several resource/power saving design approaches for various processing stages are described in the document.

  3. An on-line data acquisition system based on Norsk-Data ND-560 computer

    International Nuclear Information System (INIS)

    Bandyopadhyay, A.; Roy, A.; Dey, S.K.; Bhattacharya, S.; Bhowmik, R.K.

    1987-01-01

    This paper describes a high-speed data acquisition system based on CAMAC for Norsk Data ND-560 computer operating in a multiuser environment. As opposed to the present trend, the system has been implemented with minimum hardware at CAMAC level taking advantage of the dual processors of ND-560. The package consists of several coordinated tasks running in the two CPUs which acquire data, record on tape, permit on-line analysis and display the data and perform related control operations. It has been used in several experiments at VECC and its performance in on-line experiments is reported. (orig.)

  4. Design of Meander-Line Antennas for Radio Frequency Identification Based on Multiobjective Optimization

    Directory of Open Access Journals (Sweden)

    X. L. Travassos

    2012-01-01

    Full Text Available This paper presents optimization problem formulations to design meander-line antennas for passive UHF radio frequency identification tags based on given specifications of input impedance, frequency range, and geometric constraints. In this application, there is a need for directive transponders to select properly the target tag, which in turn must be ideally isotropic. The design of an effective meander-line antenna for RFID purposes requires balancing geometrical characteristics with the microchip impedance. Therefore, there is an issue of optimization in determining the antenna parameters for best performance. The antenna is analyzed by a method of moments. Some results using a deterministic optimization algorithm are shown.

  5. Control of single-phase islanded PV/battery minigrids based on power-line signaling

    DEFF Research Database (Denmark)

    Quintana, Pablo; Guerrero, Josep M.; Dragicevic, Tomislav

    2014-01-01

    should be utilized as efficiently as possible. This paper proposes a coordinated control strategy based on power-line signaling (PLS), instead of common communications, for a single-phase minigrid in which each unit can operate in different operation modes taking into account the resource limitation...... types of renewable energy sources (RES) and energy storage systems (ESS). Specifically, the recharging process of secondary battery, the most prominent ESS, should be done in a specific manner to preserve its life-time, microgrid line voltage must be kept within the bounds and the energy offered by RES...

  6. GRILLIX. A 3D turbulence code for magnetic fusion devices based on a field line map

    International Nuclear Information System (INIS)

    Stegmeir, Andreas Korbinian

    2015-01-01

    The complex geometry in the scrape-off layer of tokamaks poses problems to existing turbulence codes. The usually employed field aligned coordinates become ill defined at the separatrix. Therefore the parallel code GRILLIX was developed, which is based on a field line map. This allows simulations in additional complex geometries, especially across the separatrix. A new discretisation, based on the support operator method, for the highly anisotropic diffusion was developed and applied to a simple turbulence model (Hasegawa-Wakatani).

  7. Risk-based equipment removal guide for on-line maintenance at PSE ampersand G

    International Nuclear Information System (INIS)

    Knoll, A.; Smith, C.; Pollock, J.

    1995-01-01

    On-line maintenance plays an important role in achieving safe and reliable power generation in a nuclear power plant. However, maintenance, if not properly planned and performed, may also be an important contributor to plant risk. Therefore, plant-specific procedures are needed for equipment removal from service to enhance the benefits of on-line maintenance and minimize the risks involved. The problem is to identify and implement the most effective on-line maintenance policy in the form of a proceduralized guide to assure plant safety under various operation and maintenance constraints. This paper presents a methodology to develop plant-specific on-line maintenance strategies and acceptance criteria using a multivariate safety approach based on risk assessment. Based on plant-specific data as modeled in the individual plant evaluation (IPE) and the updated probabilistic safety assessment (PSA), the risk-based methodology is currently being applied to the development of proceduralized equipment removal guides at Hope Creek and Salem units 1 and 2 of Public Service Electric and Gas Company (PSE ampersand G)

  8. LINE-BASED MULTI-IMAGE MATCHING FOR FAÇADE RECONSTRUCTION

    Directory of Open Access Journals (Sweden)

    T. A. Teo

    2012-07-01

    Full Text Available This research integrates existing LOD 2 building models and multiple close-range images for façade structural lines extraction. The major works are orientation determination and multiple image matching. In the orientation determination, Speeded Up Robust Features (SURF is applied to extract tie points automatically. Then, tie points and control points are combined for block adjustment. An object-based multi-images matching is proposed to extract the façade structural lines. The 2D lines in image space are extracted by Canny operator followed by Hough transform. The role of LOD 2 building models is to correct the tilt displacement of image from different views. The wall of LOD 2 model is also used to generate hypothesis planes for similarity measurement. Finally, average normalized cross correlation is calculated to obtain the best location in object space. The test images are acquired by a nonmetric camera Nikon D2X. The total number of image is 33. The experimental results indicate that the accuracy of orientation determination is about 1 pixel from 2515 tie points and 4 control points. It also indicates that line-based matching is more flexible than point-based matching.

  9. R and D study on on-line criticality surveillance system (III)

    International Nuclear Information System (INIS)

    Yamada, Sumasu

    1999-02-01

    The Criticality Surveillance System should have high reliability and high expandability enable to apply new approaches. Under this basic concept, a basic design of the Criticality Surveillance System has been proposed in 1997. We propose here several new ideas of modification to the original design of the Criticality Surveillance System, and also reports some results of numerical analysis over the DCA experiments in 1996. In this report, first, we proposed the modification of the Criticality Surveillance System by adding a series of modules for the usage of the Feynman-α method over the γ-ray signal, because recent studies revealed that the statistical analysis of the γ-ray signal in time domain can provide very good information of the reactor decay constant even in the case of low count rate. This modification could increase the reliability of the Criticality Surveillance System over the wide range of amount of the reprocessed fuel in the tank. Last year we have developed an executable ADF program based on the Least Mean Squares, as the redundancy to the recursive ARMA model identification algorithm. However, this algorithm has a property that the convergence rate of parameter estimation becomes very slow when input data is corrupted with colored noise. To cope with this problem, we introduced a new ADF algorithm called Block ADF algorithm, which is developed to improve the convergence rate with less computational load to the computer. In Chapter 2, we showed the basic theory and a fast adaptive filter algorithm using eigenvalue reciprocals as stepsizes in Chapter 3. This new algorithm provides a stable parameter estimates with less computation as fast as the Recursive Least Squares Method. Thirdly, we introduced a notch filter for power line noise and a software. This filter has to be developed for each specific sampling frequency and specific power line frequency, however, this filter can remove not only the line spectrum of the power line frequency but also

  10. On-line interprofessional learning: introducing constructivism through enquiry-based learning and peer review.

    Science.gov (United States)

    Hughes, Matthew; Ventura, Susie; Dando, Mark

    2004-08-01

    Interest in on-line methods of learning has accelerated in recent years. There has also been an interest in developing student-centred approaches to learning and interprofessional education. This paper illustrates the issues in designing a large (more than 700 students), on-line, inter-professional module for third year, undergraduate students drawn from nine professional healthcare courses and from four campus sites. It uses an enquiry-based learning approach. The learning theories of Piaget, Vygotsky and Schön are integrated with the on-line frameworks of Salmon and Collis et al., together with conclusions drawn from the literature and our own experiences, to produce a design that encourages students to learn through participation, re-iteration, peer-review and reflection. Consideration is given to improving student motivation and attitudes towards change, both in the design and the delivery of the module.

  11. Comparison of overhead line lightning performance based on two different tower geometries

    DEFF Research Database (Denmark)

    Ebdrup, Thomas; Olason, Daniel; Bak, Claus Leth

    2014-01-01

    of the substation and transmission line is of great importance as it is a part of the 400 kV backbone between Sweden, Norway, Germany and the offshore wind farms in Horns Rev, Denmark. The new Eagle pylon has been designed with the focus of minimizing the visual impacted of overhead lines. A detailed lightning...... performance analysis of the existing Donau and the new Eagle pylon is therefore important in order to assess the risk of failure. The lightning strike analysis is based on the number of strikes expected to terminate on the line and an investigation of how many of these there may be expected to cause...... better protected from direct stroke than the phase conductors on the Donau pylon. Furthermore with respect to a backflash, the Eagle has a better performance than the Donau pylon. It is therefore concluded that the Eagle has a better lightning performance than the Donau....

  12. An Improved Seeding Algorithm of Magnetic Flux Lines Based on Data in 3D Space

    Directory of Open Access Journals (Sweden)

    Jia Zhong

    2015-05-01

    Full Text Available This paper will propose an approach to increase the accuracy and efficiency of seeding algorithms of magnetic flux lines in magnetic field visualization. To obtain accurate and reliable visualization results, the density of the magnetic flux lines should map the magnetic induction intensity, and seed points should determine the density of the magnetic flux lines. However, the traditional seeding algorithm, which is a statistical algorithm based on data, will produce errors when computing magnetic flux through subdivision of the plane. To achieve higher accuracy, more subdivisions should be made, which will reduce efficiency. This paper analyzes the errors made when the traditional seeding algorithm is used and gives an improved algorithm. It then validates the accuracy and efficiency of the improved algorithm by comparing the results of the two algorithms with results from the equivalent magnetic flux algorithm.

  13. Synthesis method based on solution regions for planar four bar straight line linkages

    International Nuclear Information System (INIS)

    Lai Rong, Yin; Cong, Mao; Jian you, Han; Tong, Yang; Juan, Huang

    2012-01-01

    An analytical method for synthesizing and selecting desired four-bar straight line mechanisms based on solution regions is presented. Given two fixed pivots, the point position and direction of the target straight line, an infinite number of mechanism solutions can be produced by employing this method, both in the general case and all three special cases. Unifying the straight line direction and the displacement from the given point to the instant center into the same form with different angles as parameters, infinite mechanism solutions can be expressed with different solution region charts. The mechanism property graphs have been computed to enable the designers to find out the involved mechanism information more intuitively and avoid aimlessness in selecting optimal mechanisms

  14. Alternating current line-filter based on electrochemical capacitor utilizing template-patterned graphene.

    Science.gov (United States)

    Wu, Zhenkun; Li, Liyi; Lin, Ziyin; Song, Bo; Li, Zhuo; Moon, Kyoung-Sik; Wong, Ching-Ping; Bai, Shu-Lin

    2015-06-17

    Aluminum electrolytic capacitors (AECs) are widely used for alternating current (ac) line-filtering. However, their bulky size is becoming more and more incompatible with the rapid development of portable electronics. Here we report a scalable process to fabricate miniaturized graphene-based ac line-filters on flexible substrates at room temperature. In this work, graphene oxide (GO) is reduced by patterned metal interdigits at room temperature and used directly as the electrode material. The as-fabricated device shows a phase angle of -75.4° at 120 Hz with a specific capacitance of 316 µF/cm(2) and a RC time constant of 0.35 ms. In addition, it retains 97.2% of the initial capacitance after 10000 charge/discharge cycles. These outstanding performance characteristics of our device demonstrate its promising to replace the conventional AECs for ac line filtering.

  15. Measurement value analysis overall equipment effectiveness (OEE) packaging process in line 2 (Case Study of PT. MBI Tbk)

    Science.gov (United States)

    Rimawan, Erry; Kholil, Muhammad; Hendri

    2018-03-01

    PT. MBI Tbk is engaged in the manufacture of beverage industry, where the company’s production is based on the magnitude of customer demand that is marketing offices that had been scattered in various regions of Indonesia. In the packaging process steps in PT.MBI through the line 3 lines including racking, canning line, bottling line. In the canning process to existing packing on Line 2 (canning line), there are some machines that are used continuously, among other Depalletizer machine, filler machine, can seamer machine, pasteurizer machine, machine FLD, Wrap Around engine, engine Shrink Wrap. Due to the large demand from customers that is relentless, therefore the calculation of overall equipment effectiveness (OEE) as a whole on line 2 (canning line) is needed in order to make improvements continuously (Continuous Improvement) at line 2 (canning line). This study aims to determine the value of overall equipment effectiveness (OEE) and Losses of the most influential of the big six OEE Losses focused on equipment or machinery as a whole into a single unit that is on the line 2, which will then be known root cause of the losses that occur from the research over the field. From the calculation of overall equipment effectiveness (OEE), there are two ratios are still poor and under world-class standards, while the ratio of the availability of 88.85% of the world-class standards by 90% and the performance ratio of 78.51% of the standard world class by 95%, whereas for quality ratio has entered the world-class standard that is equal to 99.90%. Thus the value of OEE on Line 2 line is below world class standards. In this study there were only five losses, which can be identified, and while the losses were very influential, namely the Speed Reduced Losses, losses, these losses accounted for the largest percentage of the value of the rate of 19.12%, of the results of this study losses occurred due to poor surveillance systems (less good) that causes the employee or

  16. Peculiar A star HD 43819 - A photographic region line-identification study

    International Nuclear Information System (INIS)

    Adelman, S.J.; The Citadel, Charleston, SC)

    1985-01-01

    A line identification study of the sharp-lined silicon star HD 43819 has been performed for the photographic region 3759-4924 A. Comparison of this star's spectrum with those of other silicon stars shows that it shares many of their apparent abundance anomalies. The TiII, CrII, FeI, and FeII spectra are well represented while the singly ionized rare earths are represented by at best a few lines per species. 21 references

  17. A Trajectory Correction based on Multi-Step Lining-up for the CLIC Main Linac

    CERN Document Server

    D'Amico, T E

    1999-01-01

    In the CLIC main linac it is very important to minimise the trajectory excursion and consequently the emittance dilution in order to obtain the required luminosity. Several algorithms have been proposed and lately the ballistic method has proved to be very effective. The trajectory method described in this Note retains the main advantages of the latter while adding some interesting features. It is based on the separation of the unknown variables like the quadrupole misalignments, the offset and slope of the injection straight line and the misalignments of the beam position monitors (BPM). This is achieved by referring the trajectory relatively to the injection line and not to the average pre-alignment line and by using two trajectories each corresponding to slightly different quadrupole strengths. A reference straight line is then derived onto which the beam is bent by a kick obtained by moving the first quadrupole. The other quadrupoles are then aligned on that line. The quality of the correction depends mai...

  18. Event-based plausibility immediately influences on-line language comprehension.

    Science.gov (United States)

    Matsuki, Kazunaga; Chow, Tracy; Hare, Mary; Elman, Jeffrey L; Scheepers, Christoph; McRae, Ken

    2011-07-01

    In some theories of sentence comprehension, linguistically relevant lexical knowledge, such as selectional restrictions, is privileged in terms of the time-course of its access and influence. We examined whether event knowledge computed by combining multiple concepts can rapidly influence language understanding even in the absence of selectional restriction violations. Specifically, we investigated whether instruments can combine with actions to influence comprehension of ensuing patients of (as in Rayner, Warren, Juhuasz, & Liversedge, 2004; Warren & McConnell, 2007). Instrument-verb-patient triplets were created in a norming study designed to tap directly into event knowledge. In self-paced reading (Experiment 1), participants were faster to read patient nouns, such as hair, when they were typical of the instrument-action pair (Donna used the shampoo to wash vs. the hose to wash). Experiment 2 showed that these results were not due to direct instrument-patient relations. Experiment 3 replicated Experiment 1 using eyetracking, with effects of event typicality observed in first fixation and gaze durations on the patient noun. This research demonstrates that conceptual event-based expectations are computed and used rapidly and dynamically during on-line language comprehension. We discuss relationships among plausibility and predictability, as well as their implications. We conclude that selectional restrictions may be best considered as event-based conceptual knowledge rather than lexical-grammatical knowledge.

  19. Application of reliability based design concepts to transmission line structure foundations. Part 2

    International Nuclear Information System (INIS)

    DiGioia, A.M. Jr.; Rojas-Gonzalez, L.F.

    1991-01-01

    The application of reliability based design (RBD) methods to transmission line structure foundations has developed somewhat more slowly than that for the other structural components in line systems. In a previous paper, a procedure was proposed for the design of transmission line structures foundations using a probability based load and resistance factor design (LRFD) format. This procedure involved the determination of a foundation strength factor, φ F , which was used as a multiplier of the calculated nominal design strength to estimate the five percent exclusion limit strength required in the calculated nominal design strength to estimate the five percent exclusion limit strength required in the LRFD equation. Statistical analyses of results from full-scale load tests were used to obtain φ F values applicable to various nominal design strength equations and for drilled shafts subjected to uplift loads. These results clearly illustrated the significant economic benefits of conducting more detailed subsurface investigations for the design of transmission line structure foundations. A design example was also presented. In this paper the proposed procedure is extended to laterally load drilled shafts

  20. The efficacy of levofloxacin-based triple therapy for first-line Helicobacter pylori eradication

    Directory of Open Access Journals (Sweden)

    Yusuf Aydın

    2011-06-01

    Full Text Available Standard triple therapy composed of a proton pump inhibitor, clarithromycin and amoxicillin has been widely preferred for H. pylori eradication in Turkey and World. Alternative therapies are currently under investigation because of an increase in clarithromycin resistance. The aim of this study was to evaluate the efficacy of a levoflox-acin-containing triple therapy.Materials and methods: The study was carried out in 81 H. pylori-infected patients (52 female, 29 male with nonul-cer dyspepsia. The mean age was found 46.3 ± 13.9. Treatment was indicated with lansoprazol 30 mg b.d., amoxicil-lin 1 g b.d., and levofloxacin 500 mg daily for 7 days. H. pylori status was rechecked by (14C urea breath test 6-8 weeks after the end of therapy.Results: Totally 81 patients could complete the treatment and follow-up protocol. Effectiveness was 68%. The distrib-tions of age, gender and smoking were similar between eradicated and non-eradicated groups (p > 0.05.Conclusion: Seven-day levofloxacin based triple therapy is not very effective in the first-line treatment of H. pylori in-fection. The new treatment modalities should be investigated.

  1. Studying the complex spectral line profiles in the spectra of hot emission stars and quasars .

    Science.gov (United States)

    Danezis, E.; Lyratzi, E.; Antoniou, A.; Popović, L. Č.; Dimitrijević, M. S.

    Some Hot Emission Stars and AGNs present peculiar spectral line profiles which are due to DACs and SACs phenomena. The origin and the mechanisms which are responsible for the creation of DACs/SACs is an important problem that has been studied by many researchers. This paper is a review of our efforts to study the origin and the mechanisms of these phenomena. At first we present a theoretic ad hoc picture for the structure of the plasma that surrounds the specific category of hot emission stars that present DACs or SACs. Then we present the mathematical model that we constructed, which is based on the properties of the above ad hoc theoretical structure. Finally, we present some results from our statistical studies that prove the consistency of our model with the classical physical theory.

  2. Slope and Line of Best Fit: A Transfer of Knowledge Case Study

    Science.gov (United States)

    Nagle, Courtney; Casey, Stephanie; Moore-Russo, Deborah

    2017-01-01

    This paper brings together research on slope from mathematics education and research on line of best fit from statistics education by considering what knowledge of slope students transfer to a novel task involving determining the placement of an informal line of best fit. This study focuses on two students who transitioned from placing inaccurate…

  3. Radiobiological studies with a series of human cell lines of varying glutathione content

    International Nuclear Information System (INIS)

    Astor, M.B.

    1984-01-01

    Radiation responses of a series of four human fibroblast lines obtained from a family affected with 5-oxoprolinuria were determined. Cell suspensions were irradiated under hypoxic conditions and the oxygen enhancement ratio was determined for each cell line. Results are compared with previous studies

  4. Study of cancer cell lines with Fourier transform infrared (FTIR)/vibrational absorption (VA) spectroscopy

    DEFF Research Database (Denmark)

    Uceda Otero, E. P.; Eliel, G. S. N.; Fonseca, E. J. S.

    2013-01-01

    In this work we have used Fourier transform infrared (FTIR) / vibrational absorption (VA) spectroscopy to study two cancer cell lines: the Henrietta Lacks (HeLa) human cervix carcinoma and 5637 human bladder carcinoma cell lines. Our goal is to experimentally investigate biochemical changes...

  5. A Multilayer Perceptron-Based Impulsive Noise Detector with Application to Power-Line-Based Sensor Networks

    KAUST Repository

    Chien, Ying-Ren

    2018-04-10

    For power-line-based sensor networks, impulsive noise (IN) will dramatically degrade the data transmission rate in the power line. In this paper, we present a multilayer perceptron (MLP)-based approach to detect IN in orthogonal frequency-division multiplexing (OFDM)-based baseband power line communications (PLCs). Combining the MLP-based IN detection method with the outlier detection theory allows more accurate identification of the harmful residual IN. For OFDM-based PLC systems, the high peak-to-average power ratio (PAPR) of the received signal makes detection of harmful residual IN more challenging. The detection mechanism works in an iterative receiver that contains a pre-IN mitigation and a post-IN mitigation. The pre-IN mitigation is meant to null the stronger portion of IN, while the post-IN mitigation suppresses the residual portion of IN using an iterative process. Compared with previously reported IN detectors, the simulation results show that our MLP-based IN detector improves the resulting bit error rate (BER) performance.

  6. Line-to-Line Fault Analysis and Location in a VSC-Based Low-Voltage DC Distribution Network

    Directory of Open Access Journals (Sweden)

    Shi-Min Xue

    2018-03-01

    Full Text Available A DC cable short-circuit fault is the most severe fault type that occurs in DC distribution networks, having a negative impact on transmission equipment and the stability of system operation. When a short-circuit fault occurs in a DC distribution network based on a voltage source converter (VSC, an in-depth analysis and characterization of the fault is of great significance to establish relay protection, devise fault current limiters and realize fault location. However, research on short-circuit faults in VSC-based low-voltage DC (LVDC systems, which are greatly different from high-voltage DC (HVDC systems, is currently stagnant. The existing research in this area is not conclusive, with further study required to explain findings in HVDC systems that do not fit with simulated results or lack thorough theoretical analyses. In this paper, faults are divided into transient- and steady-state faults, and detailed formulas are provided. A more thorough and practical theoretical analysis with fewer errors can be used to develop protection schemes and short-circuit fault locations based on transient- and steady-state analytic formulas. Compared to the classical methods, the fault analyses in this paper provide more accurate computed results of fault current. Thus, the fault location method can rapidly evaluate the distance between the fault and converter. The analyses of error increase and an improved handshaking method coordinating with the proposed location method are presented.

  7. The LifeLines Cohort Study: Prevalence and treatment of cardiovascular disease and risk factors

    OpenAIRE

    van der Ende, M. Yldau; Hartman, Minke H. T.; Hagemeijer, Yanick; Meems, Laura M. G.; de Vries, Hendrik Sierd; Stolk, Ronald P.; de Boer, Rudolf A.; Sijtsma, Anna; van der Meer, Peter; Rienstra, Michiel; van der Harst, Pim

    2017-01-01

    Background: The LifeLines Cohort Study is a large three-generation prospective study and Biobank. Recruitment and data collection started in 2006 and follow-up is planned for 30 years. The central aim of LifeLines is to understand healthy ageing in the 21st century. Here, the study design, methods, baseline and major cardiovascular phenotypes of the LifeLines Cohort Study are presented. Methods and results: Baseline cardiovascular phenotypeswere defined in 9700 juvenile (8-18 years) and 152,1...

  8. Gate-tunable current partition in graphene-based topological zero lines

    Science.gov (United States)

    Wang, Ke; Ren, Yafei; Deng, Xinzhou; Yang, Shengyuan A.; Jung, Jeil; Qiao, Zhenhua

    2017-06-01

    We demonstrate new mechanisms for gate-tunable current partition at topological zero-line intersections in a graphene-based current splitter. Based on numerical calculations of the nonequilibrium Green's functions and Landauer-Büttiker formula, we show that the presence of a perpendicular magnetic field on the order of a few Teslas allows for carrier sign dependent current routing. In the zero-field limit the control on current routing and partition can be achieved within a range of 10-90 % of the total incoming current by tuning the carrier density at tilted intersections or by modifying the relative magnitude of the bulk band gaps via gate voltage. We discuss the implications of our findings in the design of topological zero-line networks where finite orbital magnetic moments are expected when the current partition is asymmetric.

  9. Development of an Ethernet enabled microcontroller based module for Superconducting Cyclotron ECR beam line control

    International Nuclear Information System (INIS)

    Chatterjee, M.; Koley, D.; Nabhiraj, P.Y.

    2012-01-01

    An Ethernet enabled control and data acquisition module is developed for remote control and monitoring of the ECR beam line equipment of the Superconducting Cyclotron. The PIC microcontroller based module supports multiple general purpose analog and digital inputs and outputs for interfacing with various equipments and an embedded web server. The remote monitoring and control of the equipment are achieved through the web based user interface. The user authenticated access to control parameters and module configuration parameters ensures the operational safety of the equipment under control. This module is installed in Superconducting Cyclotron ECR beam line for the control and monitoring of vacuum pumping modules, comprising of pumps, gate valves and dual vacuum gauges. The installation of these modules results in a distributed control with localised field cabling and hence better fault diagnosis. (author)

  10. Top-Down and Bottom-Up Approach for Model-Based Testing of Product Lines

    Directory of Open Access Journals (Sweden)

    Stephan Weißleder

    2013-03-01

    Full Text Available Systems tend to become more and more complex. This has a direct impact on system engineering processes. Two of the most important phases in these processes are requirements engineering and quality assurance. Two significant complexity drivers located in these phases are the growing number of product variants that have to be integrated into the requirements engineering and the ever growing effort for manual test design. There are modeling techniques to deal with both complexity drivers like, e.g., feature modeling and model-based test design. Their combination, however, has been seldom the focus of investigation. In this paper, we present two approaches to combine feature modeling and model-based testing as an efficient quality assurance technique for product lines. We present the corresponding difficulties and approaches to overcome them. All explanations are supported by an example of an online shop product line.

  11. Product line based ontology reuse in context-aware e-business environment

    DEFF Research Database (Denmark)

    Zhang, Weishan; Kunz, Thomas

    2006-01-01

    Improving the reusability of ontology is recognized as increasingly important due to the prevalence of OWL research and applications. But there exists no convincing methodology and tool support in this direction yet. In this paper, we apply ideas from the research and practice with software product...... lines in order to explore this issue. The ontology is developed and managed according to the commonalities and variabilities underlying a specific problem domain. Meta-ontology is used in order to improve the reusability, evolve-ability and customizability of ontology. Another advantage is being able...... to generate needed ontology with the created meta-ontology implemented with XVCL (XML based Variant Configuration Language) technology. We demonstrate our product line based reuse approach with an example B2C application....

  12. DEVELOPMENT OF MELON F1 SEEDS BASED ON LINES WITH GENIC MALE STERILITY

    Directory of Open Access Journals (Sweden)

    A. S. Sokolov

    2014-01-01

    Full Text Available The perspective technology of development of melon of F1hybrids seeds by use maternal lines with an original form of genic mail sterility and marker trait (lobed leaves was studied. Elements of technology allow developing hybrid seeds of melon with hybridity of 90-95%.

  13. Genomic prediction based on data from three layer lines using non-linear regression models

    NARCIS (Netherlands)

    Huang, H.; Windig, J.J.; Vereijken, A.; Calus, M.P.L.

    2014-01-01

    Background - Most studies on genomic prediction with reference populations that include multiple lines or breeds have used linear models. Data heterogeneity due to using multiple populations may conflict with model assumptions used in linear regression methods. Methods - In an attempt to alleviate

  14. A stable murine-based RD114 retroviral packaging line efficiently transduces human hematopoietic cells.

    Science.gov (United States)

    Ward, Maureen; Sattler, Rose; Grossman, I Robert; Bell, Anthony J; Skerrett, Donna; Baxi, Laxmi; Bank, Arthur

    2003-11-01

    Several barriers exist to high-efficiency transfer of therapeutic genes into human hematopoietic stem cells (HSCs) using complex oncoretroviral vectors. Human clinical trials to date have used Moloney leukemia virus-based amphotropic and gibbon ape leukemia virus-based envelopes in stable retroviral packaging lines. However, retroviruses pseudotyped with these envelopes have low titers due to the inability to concentrate viral supernatants efficiently by centrifugation without damaging the virus and low transduction efficiencies because of low-level expression of viral target receptors on human HSC. The RD114 envelope from the feline endogenous virus has been shown to transduce human CD34+ cells using transient packaging systems and to be concentrated to high titers by centrifugation. Stable packaging systems have potential advantages over transient systems because greater and more reproducible viral productions can be attained. We have, therefore, constructed and tested a stable RD114-expressing packaging line capable of high-level transduction of human CD34+ cells. Viral particles from this cell line were concentrated up to 100-fold (up to 10(7) viral particles/ml) by ultracentrifugation. Human hematopoietic progenitors from cord blood and sickle cell CD34+ cells were efficiently transduced with a Neo(R)-containing vector after a single exposure to concentrated RD114-pseudotyped virus produced from this cell line. Up to 78% of progenitors from transduced cord blood CD34+ cells and 51% of progenitors from sickle cell CD34+ cells expressed the NeoR gene. We also show transfer of a human beta-globin gene into progenitor cells from CD34+ cells from sickle cell patients with this new RD114 stable packaging system. The results indicate that this packaging line may eventually be useful in human clinical trials of globin gene therapy.

  15. Retrospective analysis of first-line treatment for follicular lymphoma based on outcomes and medical economics.

    Science.gov (United States)

    Muneishi, Manaka; Nakamura, Ayaka; Tachibana, Katsumi; Suemitsu, Junko; Hasebe, Shinji; Takeuchi, Kazuto; Yakushijin, Yoshihiro

    2018-04-01

    Follicular lymphoma (FL) is the most common type of non-Hodgkin lymphoma (NHL), with indolent progression. Several treatment options are selected, based not only on disease status, quality of life (QOL), and age of patient, but also on recent increasing medical costs. We retrospectively analysed the first-line treatment of FL with regard to treatment outcomes and medical economics, and discuss the appropriate strategies for FL. Data on a total of 69 newly-diagnosed patients with FL was retrospectively collected from 2001 to 2015. The median age of the patients was 60 years and the median follow-up was 58 months. A total of 25 cases with FL were treated with R monotherapy, and 28 cases were treated with R-CHOP as first-line treatment. The factors affecting the decision of physicians to use R or R-CHOP treatment were serum level of lactate dehydrogenase (LDH) and disease stage. The first-line treatment-associated survival did not show any statistical differences between R and R-CHOP. The average hospitalization and average of all medical costs during the first-line treatment were 4.1 days (R) versus 55.7 days (R-CHOP), and JPY 1,707,693 (USD 15,324) (R) versus JPY 2,136,117 (USD 19,170) (R-CHOP), respectively. R monotherapy for patients whose diseases show low tumor burden and who are not candidates for local treatment has benefits as a first-line treatment compared to R-CHOP, based on the patients' QOL and medical economics.

  16. Numerically-based ducted propeller design using vortex lattice lifting line theory

    OpenAIRE

    Stubblefield, John M.

    2008-01-01

    CIVINS (Civilian Institutions) Thesis document This thesis used vortex lattice lifting line theory to model an axisymmetrical-ducted propeller with no gap between the duct and the propeller. The theory required to model the duct and its interaction with the propeller were discussed and implemented in Open-source Propeller Design and Analysis Program (OpenProp). Two routines for determining the optimum circulation distribution were considered, and a method based on calculus of variation...

  17. Implementation of a microcomputer based distance relay for parallel transmission lines

    International Nuclear Information System (INIS)

    Phadke, A.G.; Jihuang, L.

    1986-01-01

    Distance relaying for parallel transmission lines is a difficult application problem with conventional phase and ground distance relays. It is known that for cross-country faults involving dissimilar phases and ground, three phase tripping may result. This paper summarizes a newly developed microcomputer based relay which is capable of classifying the cross-country fault correctly. The paper describes the principle of operation and results of laboratory tests of this relay

  18. Study of the cell cycle control for human malignant mesothelioma lines. Interferon and radiations effect

    International Nuclear Information System (INIS)

    Vivo, C.

    1999-01-01

    In order to better understand the inhibition mechanisms of the IFN-R-HU on tumoral development, the IFN-R-U effect on MM lines has been studied. Three groups of lines has been distinguished: eight sensitive lines, two intermediate and three resistant. The sensitive lines showed a triple locking of the cell cycle: in phases S, G1 and G2. The study of the cell cycle control points function, realized by the MM lines radiation exposure showed the points function on G1/S and-or on G2/M and the dependence or non dependence of the cycle stop of the protein P53 and P21 W at F1/CIP1. (A.L.B.)

  19. Study of Opacity Effects on Emission Lines at EXTRAP T2R RFP

    Science.gov (United States)

    Stancalie, Viorica; Rachlew, Elisabeth

    We have investigated the influence of opacity on hydrogen (H-α and Ly-β) and Li-like oxygen emission lines from the EXTRAP T2R reversed field pinch. We used the Atomic Data Analysis System (AzDAS) based on the escape factor approximation for radiative transfer to calculate metastable and excited population densities via a collisional-radiative model. Population escape factor, emergent escape factor and modified line profiles are plotted vs. optical depth. The simulated emission line ratios in the density/temperature plane are in good agreement with experimental data for electron density and temperature measurements.

  20. Local high precision 3D measurement based on line laser measuring instrument

    Science.gov (United States)

    Zhang, Renwei; Liu, Wei; Lu, Yongkang; Zhang, Yang; Ma, Jianwei; Jia, Zhenyuan

    2018-03-01

    In order to realize the precision machining and assembly of the parts, the geometrical dimensions of the surface of the local assembly surfaces need to be strictly guaranteed. In this paper, a local high-precision three-dimensional measurement method based on line laser measuring instrument is proposed to achieve a high degree of accuracy of the three-dimensional reconstruction of the surface. Aiming at the problem of two-dimensional line laser measuring instrument which lacks one-dimensional high-precision information, a local three-dimensional profile measuring system based on an accurate single-axis controller is proposed. First of all, a three-dimensional data compensation method based on spatial multi-angle line laser measuring instrument is proposed to achieve the high-precision measurement of the default axis. Through the pretreatment of the 3D point cloud information, the measurement points can be restored accurately. Finally, the target spherical surface is needed to make local three-dimensional scanning measurements for accuracy verification. The experimental results show that this scheme can get the local three-dimensional information of the target quickly and accurately, and achieves the purpose of gaining the information and compensating the error for laser scanner information, and improves the local measurement accuracy.

  1. Line-Based Registration of Panoramic Images and LiDAR Point Clouds for Mobile Mapping

    Directory of Open Access Journals (Sweden)

    Tingting Cui

    2016-12-01

    Full Text Available For multi-sensor integrated systems, such as the mobile mapping system (MMS, data fusion at sensor-level, i.e., the 2D-3D registration between an optical camera and LiDAR, is a prerequisite for higher level fusion and further applications. This paper proposes a line-based registration method for panoramic images and a LiDAR point cloud collected by a MMS. We first introduce the system configuration and specification, including the coordinate systems of the MMS, the 3D LiDAR scanners, and the two panoramic camera models. We then establish the line-based transformation model for the panoramic camera. Finally, the proposed registration method is evaluated for two types of camera models by visual inspection and quantitative comparison. The results demonstrate that the line-based registration method can significantly improve the alignment of the panoramic image and the LiDAR datasets under either the ideal spherical or the rigorous panoramic camera model, with the latter being more reliable.

  2. A Sea-Sky Line Detection Method for Unmanned Surface Vehicles Based on Gradient Saliency.

    Science.gov (United States)

    Wang, Bo; Su, Yumin; Wan, Lei

    2016-04-15

    Special features in real marine environments such as cloud clutter, sea glint and weather conditions always result in various kinds of interference in optical images, which make it very difficult for unmanned surface vehicles (USVs) to detect the sea-sky line (SSL) accurately. To solve this problem a saliency-based SSL detection method is proposed. Through the computation of gradient saliency the line features of SSL are enhanced effectively, while other interference factors are relatively suppressed, and line support regions are obtained by a region growing method on gradient orientation. The SSL identification is achieved according to region contrast, line segment length and orientation features, and optimal state estimation of SSL detection is implemented by introducing a cubature Kalman filter (CKF). In the end, the proposed method is tested on a benchmark dataset from the "XL" USV in a real marine environment, and the experimental results demonstrate that the proposed method is significantly superior to other state-of-the-art methods in terms of accuracy rate and real-time performance, and its accuracy and stability are effectively improved by the CKF.

  3. Agent-based station for on-line diagnostics by self-adaptive laser Doppler vibrometry.

    Science.gov (United States)

    Serafini, S; Paone, N; Castellini, P

    2013-12-01

    A self-adaptive diagnostic system based on laser vibrometry is proposed for quality control of mechanical defects by vibration testing; it is developed for appliances at the end of an assembly line, but its characteristics are generally suited for testing most types of electromechanical products. It consists of a laser Doppler vibrometer, equipped with scanning mirrors and a camera, which implements self-adaptive bahaviour for optimizing the measurement. The system is conceived as a Quality Control Agent (QCA) and it is part of a Multi Agent System that supervises all the production line. The QCA behaviour is defined so to minimize measurement uncertainty during the on-line tests and to compensate target mis-positioning under guidance of a vision system. Best measurement conditions are reached by maximizing the amplitude of the optical Doppler beat signal (signal quality) and consequently minimize uncertainty. In this paper, the optimization strategy for measurement enhancement achieved by the down-hill algorithm (Nelder-Mead algorithm) and its effect on signal quality improvement is discussed. Tests on a washing machine in controlled operating conditions allow to evaluate the efficacy of the method; significant reduction of noise on vibration velocity spectra is observed. Results from on-line tests are presented, which demonstrate the potential of the system for industrial quality control.

  4. Discrete PSO algorithm based optimization of transmission lines loading in TNEP problem

    International Nuclear Information System (INIS)

    Shayeghi, H.; Mahdavi, M.; Bagheri, A.

    2010-01-01

    Transmission network expansion planning (TNEP) is a basic part of power system planning that determines where, when and how many new transmission lines should be added to the network. Up till now, various methods have been presented to solve the static transmission network expansion planning (STNEP) problem. But in all of these methods, lines adequacy rate has not been considered at the end of planning horizon, i.e. expanded network misses adequacy after some times and needs to be expanded again. In this paper, expansion planning has been implemented by merging lines loading parameter in the STNEP and inserting investment cost into the fitness function constraints using discrete particle swarm optimization (DPSO) algorithm. Expanded network will possess a maximum adequacy to provide load demand and also the transmission lines overloaded later. The proposed idea has been tested on the Garvers network and an actual transmission network of the Azerbaijan regional electric company, Iran, and the results are compared with the decimal codification genetic algorithm (DCGA) technique. The results evaluation shows that the network will possess maximum efficiency economically. Also, it is shown that precision and convergence speed of the proposed DPSO based method for the solution of the STNEP problem is superior to DCGA approach.

  5. Agent-based station for on-line diagnostics by self-adaptive laser Doppler vibrometry

    Science.gov (United States)

    Serafini, S.; Paone, N.; Castellini, P.

    2013-12-01

    A self-adaptive diagnostic system based on laser vibrometry is proposed for quality control of mechanical defects by vibration testing; it is developed for appliances at the end of an assembly line, but its characteristics are generally suited for testing most types of electromechanical products. It consists of a laser Doppler vibrometer, equipped with scanning mirrors and a camera, which implements self-adaptive bahaviour for optimizing the measurement. The system is conceived as a Quality Control Agent (QCA) and it is part of a Multi Agent System that supervises all the production line. The QCA behaviour is defined so to minimize measurement uncertainty during the on-line tests and to compensate target mis-positioning under guidance of a vision system. Best measurement conditions are reached by maximizing the amplitude of the optical Doppler beat signal (signal quality) and consequently minimize uncertainty. In this paper, the optimization strategy for measurement enhancement achieved by the down-hill algorithm (Nelder-Mead algorithm) and its effect on signal quality improvement is discussed. Tests on a washing machine in controlled operating conditions allow to evaluate the efficacy of the method; significant reduction of noise on vibration velocity spectra is observed. Results from on-line tests are presented, which demonstrate the potential of the system for industrial quality control.

  6. A 2.9 ps equivalent resolution interpolating time counter based on multiple independent coding lines

    International Nuclear Information System (INIS)

    Szplet, R; Jachna, Z; Kwiatkowski, P; Rozyc, K

    2013-01-01

    We present the design, operation and test results of a time counter that has an equivalent resolution of 2.9 ps, a measurement uncertainty at the level of 6 ps, and a measurement range of 10 s. The time counter has been implemented in a general-purpose reprogrammable device Spartan-6 (Xilinx). To obtain both high precision and wide measurement range the counting of periods of a reference clock is combined with a two-stage interpolation within a single period of the clock signal. The interpolation involves a four-phase clock in the first interpolation stage (FIS) and an equivalent coding line (ECL) in the second interpolation stage (SIS). The ECL is created as a compound of independent discrete time coding lines (TCL). The number of TCLs used to create the virtual ECL has an effect on its resolution. We tested ECLs made from up to 16 TCLs, but the idea may be extended to a larger number of lines. In the presented time counter the coarse resolution of the counting method equal to 2 ns (period of the 500 MHz reference clock) is firstly improved fourfold in the FIS and next even more than 400 times in the SIS. The proposed solution allows us to overcome the technological limitation in achievable resolution and improve the precision of conversion of integrated interpolators based on tapped delay lines. (paper)

  7. A Sea-Sky Line Detection Method for Unmanned Surface Vehicles Based on Gradient Saliency

    Directory of Open Access Journals (Sweden)

    Bo Wang

    2016-04-01

    Full Text Available Special features in real marine environments such as cloud clutter, sea glint and weather conditions always result in various kinds of interference in optical images, which make it very difficult for unmanned surface vehicles (USVs to detect the sea-sky line (SSL accurately. To solve this problem a saliency-based SSL detection method is proposed. Through the computation of gradient saliency the line features of SSL are enhanced effectively, while other interference factors are relatively suppressed, and line support regions are obtained by a region growing method on gradient orientation. The SSL identification is achieved according to region contrast, line segment length and orientation features, and optimal state estimation of SSL detection is implemented by introducing a cubature Kalman filter (CKF. In the end, the proposed method is tested on a benchmark dataset from the “XL” USV in a real marine environment, and the experimental results demonstrate that the proposed method is significantly superior to other state-of-the-art methods in terms of accuracy rate and real-time performance, and its accuracy and stability are effectively improved by the CKF.

  8. Experimental studies on coherent synchrotron radiaiton in the emittance exchange line at the Fermilab A0 Photoinjector

    International Nuclear Information System (INIS)

    Thangaraj, J.C.T.; Keup, R.; Johnson, A.; Ruan, J.; Piot, P.; Church, M.; Edwards, H.; Lumpkin, A.; Sun, Y.-E.; Santucci, J.

    2011-01-01

    Future accelerators will employ advanced beam conditioning systems such as emittance exchangers to manipulate high brightness beams. Coherent synchrotron radiation (CSR) in the dipoles could limit the performance of the emittance exchanger. In this paper, we report the experimental studies on measuring CSR and its effects on the beam at the A0 photoinjector in the emittance exchange line. After reporting the CSR power measurements, we report on the diagnostic scheme based on a weak skew quad in the emittance exchange line to study the CSR effects on the beam and other beam dynamics. In this work, we have reported on CSR measurements and the effect of skew quad on the dogleg line with the 5-cell turned on and off. We plan to study CSR effects on the bunch with the 5-cell on at larger chirp. This is will not only increase the CSR self-effect but also reduce the beamsize at the screen for convenient beamsize measurements.

  9. Research on a Lamb Wave and Particle Filter-Based On-Line Crack Propagation Prognosis Method

    OpenAIRE

    Chen, Jian; Yuan, Shenfang; Qiu, Lei; Cai, Jian; Yang, Weibo

    2016-01-01

    Prognostics and health management techniques have drawn widespread attention due to their ability to facilitate maintenance activities based on need. On-line prognosis of fatigue crack propagation can offer information for optimizing operation and maintenance strategies in real-time. This paper proposes a Lamb wave-particle filter (LW-PF)-based method for on-line prognosis of fatigue crack propagation which takes advantages of the possibility of on-line monitoring to evaluate the actual crack...

  10. BLACK HOLE MASS ESTIMATES BASED ON C IV ARE CONSISTENT WITH THOSE BASED ON THE BALMER LINES

    Energy Technology Data Exchange (ETDEWEB)

    Assef, R. J.; Denney, K. D.; Kochanek, C. S.; Peterson, B. M.; Kozlowski, S.; Dietrich, M.; Grier, C. J.; Khan, R. [Department of Astronomy, The Ohio State University, 140 W. 18th Ave., Columbus, OH 43210 (United States); Ageorges, N.; Buschkamp, P.; Gemperlein, H.; Hofmann, R. [Max-Planck-Institut fuer Extraterrestrische Physik, Giessenbachstr., D-85748 Garching (Germany); Barrows, R. S. [Arkansas Center for Space and Planetary Sciences, University of Arkansas, Fayetteville, AR 72701 (United States); Falco, E.; Kilic, M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Feiz, C.; Germeroth, A. [Landessternwarte, ZAH, Koenigstuhl 12, D-69117 Heidelberg (Germany); Juette, M.; Knierim, V. [Astron. Institut der Ruhr Univ. Bochum, Universitaetsstr. 150, D-44780 Bochum (Germany); Laun, W., E-mail: rjassef@astronomy.ohio-state.edu [Max-Planck-Institut fuer Astronomie, Koenigstuhl 17, D-69117 Heidelberg (Germany); and others

    2011-12-01

    Using a sample of high-redshift lensed quasars from the CASTLES project with observed-frame ultraviolet or optical and near-infrared spectra, we have searched for possible biases between supermassive black hole (BH) mass estimates based on the C IV, H{alpha}, and H{beta} broad emission lines. Our sample is based upon that of Greene, Peng, and Ludwig, expanded with new near-IR spectroscopic observations, consistently analyzed high signal-to-noise ratio (S/N) optical spectra, and consistent continuum luminosity estimates at 5100 A. We find that BH mass estimates based on the full width at half-maximum (FWHM) of C IV show a systematic offset with respect to those obtained from the line dispersion, {sigma}{sub l}, of the same emission line, but not with those obtained from the FWHM of H{alpha} and H{beta}. The magnitude of the offset depends on the treatment of the He II and Fe II emission blended with C IV, but there is little scatter for any fixed measurement prescription. While we otherwise find no systematic offsets between C IV and Balmer line mass estimates, we do find that the residuals between them are strongly correlated with the ratio of the UV and optical continuum luminosities. This means that much of the dispersion in previous comparisons of C IV and H{beta} BH mass estimates are due to the continuum luminosities rather than to any properties of the lines. Removing this dependency reduces the scatter between the UV- and optical-based BH mass estimates by a factor of approximately two, from roughly 0.35 to 0.18 dex. The dispersion is smallest when comparing the C IV {sigma}{sub l} mass estimate, after removing the offset from the FWHM estimates, and either Balmer line mass estimate. The correlation with the continuum slope is likely due to a combination of reddening, host contamination, and object-dependent SED shapes. When we add additional heterogeneous measurements from the literature, the results are unchanged. Moreover, in a trial observation of a

  11. Study of pitting corrosion in line-pipe steel under the influence of remanent magnetization

    Energy Technology Data Exchange (ETDEWEB)

    Espina-Hernandez, J H; Caleyo, F; Hallen, J M [Instituto Politecnico Nacional (IPN), Zacatenco (Mexico)

    2009-07-01

    The influence of remanent magnetization on pitting corrosion in line-pipe steels is studied. Pitting corrosion experiments have been carried out on samples of an API 5L grade 52 steel under a magnetization level of the same order of magnitude of the remanent magnetization in the pipeline wall after in-line inspection based on magnetic flux leakage. The samples were magnetized using rings of the same grade as the investigated steel. Immediately after magnetization, the investigated samples were subjected to pitting by immersing them in a solution containing dissolved Cl{sup -} and SO{sup 2-}{sub 4} and ions. The pitting experiments were conducted during a seven days period. The pit depth distribution and the maximum pit depth in each sample were recorded and used to conduct extreme value analyses of the pitting process in magnetized and non-magnetized control samples. The statistical assessment of the pitting corrosion data collected during this study shows that the magnetic field reduces the average depth of the pit population and also the extreme pit depth values that can be predicted from the maximum values observed in the magnetized samples in comparison with to the non-magnetized control samples. Scanning electron microscopy observations show that the magnetic field alters the pit morphology by increasing the pit mouth opening. (author)

  12. An experimental study on the low-dose radiosensitivity of tumor cell lines

    International Nuclear Information System (INIS)

    Kim, Min Sook; Koh, Kwang Joon

    1994-01-01

    The purpose of this study was to aid in the radiation therapy of head and neck cancer patients. For this study, radiation survival curves were generated for B16, MG-63 and YAC-1 cell lines using semiautomated MTT assay and Dye Exclusion Assay. Irradiation of 2, 4, 6, 8, 10 Gy were delivered at room temperature at a dose rate of 210.2 cGy/min using 60 COγ-ray irradiator ALDORADO 8. The viable cells were determined for each radiation dose and compared to control values. The obtained results were as follows: 1. The was significantly different absorbance at 10 Gy on B16 cell line in MTT assay (P<0.05). 2. There was significantly different absorbance at 4, 6, 8, 10 Gy on MG-63 cell line in MTT assay (P<0.05). 3. YAC-1 cell line was more sensitive than B16 or MG-63 cell line to all doses of radiation (P<0.05). 4. There was significantly different absorbance among all tumor cell lines except between B16 and MG-63 cell line at 2 Gy in MTT assay (P<0.05). 5. Good correlation was obtained between MTT assay and DEA (P<0.05). The efficient of correlation of B16, MG-63 and YAC-1 cell line was 0.845-0.824 and 0.906, respectively.

  13. Determination of High-Frequency Current Distribution Using EMTP-Based Transmission Line Models with Resulting Radiated Electromagnetic Fields

    Energy Technology Data Exchange (ETDEWEB)

    Mork, B; Nelson, R; Kirkendall, B; Stenvig, N

    2009-11-30

    Application of BPL technologies to existing overhead high-voltage power lines would benefit greatly from improved simulation tools capable of predicting performance - such as the electromagnetic fields radiated from such lines. Existing EMTP-based frequency-dependent line models are attractive since their parameters are derived from physical design dimensions which are easily obtained. However, to calculate the radiated electromagnetic fields, detailed current distributions need to be determined. This paper presents a method of using EMTP line models to determine the current distribution on the lines, as well as a technique for using these current distributions to determine the radiated electromagnetic fields.

  14. Line profile studies of hydrodynamical models of cometary compact H II regions

    International Nuclear Information System (INIS)

    Zhu, Feng-Yao; Zhu, Qing-Feng

    2015-01-01

    We simulate the evolution of cometary H II regions based on several champagne flow models and bow shock models, and calculate the profiles of the [Ne II] fine-structure line at 12.81 μm, the H30α recombination line and the [Ne III] fine-structure line at 15.55 μm for these models at different inclinations of 0°, 30° and 60°. We find that the profiles in the bow shock models are generally different from those in the champagne flow models, but the profiles in the bow shock models with lower stellar velocity (≤ 5 km s −1 ) are similar to those in the champagne flow models. In champagne flow models, both the velocity of peak flux and the flux weighted central velocities of all three lines point outward from molecular clouds. In bow shock models, the directions of these velocities depend on the speed of stars. The central velocities of these lines are consistent with the stellar motion in the high stellar speed cases, but they are opposite directions from the stellar motion in the low speed cases. We notice that the line profiles from the slit along the symmetrical axis of the projected 2D image of these models are useful for distinguishing bow shock models from champagne flow models. It is also confirmed by the calculation that the flux weighted central velocity and the line luminosity of the [Ne III] line can be estimated from the [Ne II] line and the H30α line. (paper)

  15. A rank-based algorithm of differential expression analysis for small cell line data with statistical control.

    Science.gov (United States)

    Li, Xiangyu; Cai, Hao; Wang, Xianlong; Ao, Lu; Guo, You; He, Jun; Gu, Yunyan; Qi, Lishuang; Guan, Qingzhou; Lin, Xu; Guo, Zheng

    2017-10-13

    To detect differentially expressed genes (DEGs) in small-scale cell line experiments, usually with only two or three technical replicates for each state, the commonly used statistical methods such as significance analysis of microarrays (SAM), limma and RankProd (RP) lack statistical power, while the fold change method lacks any statistical control. In this study, we demonstrated that the within-sample relative expression orderings (REOs) of gene pairs were highly stable among technical replicates of a cell line but often widely disrupted after certain treatments such like gene knockdown, gene transfection and drug treatment. Based on this finding, we customized the RankComp algorithm, previously designed for individualized differential expression analysis through REO comparison, to identify DEGs with certain statistical control for small-scale cell line data. In both simulated and real data, the new algorithm, named CellComp, exhibited high precision with much higher sensitivity than the original RankComp, SAM, limma and RP methods. Therefore, CellComp provides an efficient tool for analyzing small-scale cell line data. © The Author 2017. Published by Oxford University Press.

  16. Coagulation sensors based on magnetostrictive delay lines for biomedical and chemical engineering applications

    International Nuclear Information System (INIS)

    Maliaritsi, E.; Zoumpoulakis, L.; Simitzis, J.; Vassiliou, P.; Hristoforou, E.

    2006-01-01

    Coagulation sensors based on the magnetostrictive delay line technique are presented in this paper. They are based on magnetostrictive ribbons and are used for measuring the coagulation, curing or solidification time of different liquids. Experimental results indicate that the presented sensing elements can determine the blood coagulation with remarkable repeatability, thus allowing their use as blood coagulation sensors. Additionally, results indicate that they can also measure curing time of resins, solidification of fluids and coagulation of chemical substances, therefore allowing their implementation in chemical engineering applications

  17. STUDY OF TRANSMISSION LINES EFFECT ON THE SYSTEM OPERATIONON OF CONTINUOUS AUTOMATIC CAB SIGNALLING

    Directory of Open Access Journals (Sweden)

    O. O. Hololobova

    2014-10-01

    Full Text Available Purpose. To conduct an effect research of the electromagnetic field of high-voltage transmission lines (HVTL (750 kV, 50 Hz on the track circuits and continuous automatic cab signalling (CACS with a signal current of 50 Hz in the areas of convergence and intersection with the transmission lines and to propose possible methods to improve noise immunity of CACS. Methodology. The measurements were performed both by means of car-laboratory and directly on rail lines. During the study the electric field strength in the range of industrial frequency directly under the transmission lines and at the distance from it to the railway lines was measured, as well as the time dependence of CACS codes with signal current frequency of 50 Hz directly under the transmission lines and at a distance from it in the absence of the train and its passing. Findings. The root causes analysis of CACS faults and failures was carried out. The effect of the electromagnetic field of high-voltage transmission lines (750 kV, 50 Hz on the track circuit and CACS with signal current of 50 Hz in the areas of convergence and intersection with the transmission line was investigated. Possible methods to improve noise immunity of CACS were considered. Originality. The effect research of transmission lines (750 kV on the operation of the automatic cab signalling on spans Prishib-Burchatsk and Privolnoye-Yelizarovo, Pridneprovsk railway in places of oblique railroads crossing and transmission lines (750 kV, 50 Hz was conducted. Electric field strength in the range of industrial frequency directly under the transmission lines and at a distance from it to the railway line, as well as the time dependences of ALSN codes with signal current frequency of 50 Hz directly under the transmission lines and at a distance from it in the absence of the train and as its passing were measured. It was found that CACS codes in track circuits under transmission lines are strongly distorted, as strength

  18. Dynamic neural networks based on-line identification and control of high performance motor drives

    Science.gov (United States)

    Rubaai, Ahmed; Kotaru, Raj

    1995-01-01

    In the automated and high-tech industries of the future, there wil be a need for high performance motor drives both in the low-power range and in the high-power range. To meet very straight demands of tracking and regulation in the two quadrants of operation, advanced control technologies are of a considerable interest and need to be developed. In response a dynamics learning control architecture is developed with simultaneous on-line identification and control. the feature of the proposed approach, to efficiently combine the dual task of system identification (learning) and adaptive control of nonlinear motor drives into a single operation is presented. This approach, therefore, not only adapts to uncertainties of the dynamic parameters of the motor drives but also learns about their inherent nonlinearities. In fact, most of the neural networks based adaptive control approaches in use have an identification phase entirely separate from the control phase. Because these approaches separate the identification and control modes, it is not possible to cope with dynamic changes in a controlled process. Extensive simulation studies have been conducted and good performance was observed. The robustness characteristics of neuro-controllers to perform efficiently in a noisy environment is also demonstrated. With this initial success, the principal investigator believes that the proposed approach with the suggested neural structure can be used successfully for the control of high performance motor drives. Two identification and control topologies based on the model reference adaptive control technique are used in this present analysis. No prior knowledge of load dynamics is assumed in either topology while the second topology also assumes no knowledge of the motor parameters.

  19. Principal components based support vector regression model for on-line instrument calibration monitoring in NPPs

    International Nuclear Information System (INIS)

    Seo, In Yong; Ha, Bok Nam; Lee, Sung Woo; Shin, Chang Hoon; Kim, Seong Jun

    2010-01-01

    In nuclear power plants (NPPs), periodic sensor calibrations are required to assure that sensors are operating correctly. By checking the sensor's operating status at every fuel outage, faulty sensors may remain undetected for periods of up to 24 months. Moreover, typically, only a few faulty sensors are found to be calibrated. For the safe operation of NPP and the reduction of unnecessary calibration, on-line instrument calibration monitoring is needed. In this study, principal component based auto-associative support vector regression (PCSVR) using response surface methodology (RSM) is proposed for the sensor signal validation of NPPs. This paper describes the design of a PCSVR-based sensor validation system for a power generation system. RSM is employed to determine the optimal values of SVR hyperparameters and is compared to the genetic algorithm (GA). The proposed PCSVR model is confirmed with the actual plant data of Kori Nuclear Power Plant Unit 3 and is compared with the Auto-Associative support vector regression (AASVR) and the auto-associative neural network (AANN) model. The auto-sensitivity of AASVR is improved by around six times by using a PCA, resulting in good detection of sensor drift. Compared to AANN, accuracy and cross-sensitivity are better while the auto-sensitivity is almost the same. Meanwhile, the proposed RSM for the optimization of the PCSVR algorithm performs even better in terms of accuracy, auto-sensitivity, and averaged maximum error, except in averaged RMS error, and this method is much more time efficient compared to the conventional GA method

  20. Study of the hydration of globular proteins by broad NMR lines method

    Energy Technology Data Exchange (ETDEWEB)

    Blicharska, B [Uniwersytet Jagiellonski, Krakow (Poland). Instytut Fizyki

    1973-01-01

    Spectra of proteins and polypeptides obtained by means of a NMR broad line spectrometer consist of broad and thin lines. These broad and thin lines are attributed to proteins and to water absorbed on the surfaces of proteins respectively. The behaviour of the thin line in the spectra of lyophilizated albumin of the egg white has been studied in the temperature range from -42 to 20/sup 0/C. The amount of water has been found by the simple method of weighing and has been equal about 7% of the total weight. It has been found that the water absorbed on the surface of the lyophilizated proteins gives a thinner line in comparison to the water absorbed on molecules of proteins in water solutions and that the correlation time is about 10/sup 3/ times greater.

  1. A detailed study on the interaction of a novel water-soluble glycine bridged zinc(II) Schiff base coordination polymer with BSA: synthesis, crystal structure, molecular docking and cytotoxicity effect against A549, Jurkat and Raji cell lines

    Czech Academy of Sciences Publication Activity Database

    Asadi, Z.; Golchin, M.; Eigner, Václav; Dušek, Michal; Amirghofran, Z.

    2017-01-01

    Roč. 465, Aug (2017), s. 50-60 ISSN 0020-1693 R&D Projects: GA MŠk LO1603; GA ČR(CZ) GA14-03276S EU Projects: European Commission(XE) CZ.2.16/3.1.00/24510 Institutional support: RVO:68378271 Keywords : water-soluble * coordination polymer * BSA * docking study * anticancer activity Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 2.002, year: 2016

  2. A model-based approach to on-line process disturbance management

    International Nuclear Information System (INIS)

    Kim, I.S.

    1988-01-01

    The methodology developed can be applied to the design of a real-time expert system to aid control-room operators in coping with process abnormalities. The approach encompasses diverse functional aspects required for an effective on-line process disturbance management: (1) intelligent process monitoring and alarming, (2) on-line sensor data validation, (3) on-line sensor and hardware (except sensors) fault diagnosis, and (4) real-time corrective measure synthesis. Accomplishment of these functions is made possible through the application of various models, goal-tree success-tree, process monitor-tree, sensor failure diagnosis, and hardware failure diagnosis models. The models used in the methodology facilitate not only the knowledge-acquisition process - a bottleneck in the development of an expert system - but also the reasoning process of the knowledge-based system. These transparent models and model-based reasoning significantly enhance the maintainability of the real-time expert systems. The proposed approach was applied to the feedwater control system of a nuclear power plant, and implemented into a real-time expert system, MOAS II, using the expert system shell, PICON, on the LMI machine

  3. A low dead time vernier delay line TDC implemented in an Actel flash-based FPGA

    International Nuclear Information System (INIS)

    Qin Xi; Feng Changqing; Zhang Deliang; Zhao Lei; Liu Shubin; An Qi

    2013-01-01

    In this paper, a high precision vernier delay line (VDL) TDC (Time-to-Digital Converter) in an Actel flash-based Field-Programmable-Gate-Arrays A3PE1500 is implemented, achieving a resolution of 16.4-ps root mean square value or 42-ps averaged bin size. The TDC has a dead time of about 200 ns while the dynamic range is 655.36 Vs. The double delay lines method is employed to cut the dead time in half to improve its performance. As the bin size of the TDC is dependent on temperature, a compensation algorithm is adopted as temperature drift correction, and the TDC shows satisfying performance in a temperature range from -5℃ to +55℃. (authors)

  4. Fuzzy-Wavelet Based Double Line Transmission System Protection Scheme in the Presence of SVC

    Science.gov (United States)

    Goli, Ravikumar; Shaik, Abdul Gafoor; Tulasi Ram, Sankara S.

    2015-06-01

    Increasing the power transfer capability and efficient utilization of available transmission lines, improving the power system controllability and stability, power oscillation damping and voltage compensation have made strides and created Flexible AC Transmission (FACTS) devices in recent decades. Shunt FACTS devices can have adverse effects on distance protection both in steady state and transient periods. Severe under reaching is the most important problem of relay which is caused by current injection at the point of connection to the system. Current absorption of compensator leads to overreach of relay. This work presents an efficient method based on wavelet transforms, fault detection, classification and location using Fuzzy logic technique which is almost independent of fault impedance, fault distance and fault inception angle. The proposed protection scheme is found to be fast, reliable and accurate for various types of faults on transmission lines with and without Static Var compensator at different locations and with various incidence angles.

  5. Radiation source states on-line supervision system design and implementation based on RFID technology

    International Nuclear Information System (INIS)

    Yang Binhua; Ling Qiu; Yin Guoli; Yang Kun; Wan Xueping; Wang Kan

    2011-01-01

    It puts forward radiation source states on-line monitoring resolution based on RFID technology. Firstly, the system uses RFID in real-time transmission of the radiation dose rate, and monitors the radiation source states and dose rate of the surrounding environment on-line. Then it adopts regional wireless networking mode to construct enterprise level monitoring network, which resolves long-distance wiring problems. And then it uses GPRS wireless to transport the real-time data to the monitoring center and the government supervision department, By adopting randomly dynamic cording in display update every day, it strengthens the supervision of the radiation source. At last this system has been successful applied to a thickness gauge project, which verifies the feasibility and practicality is good. (authors)

  6. Verification test for on-line diagnosis algorithm based on noise analysis

    International Nuclear Information System (INIS)

    Tamaoki, T.; Naito, N.; Tsunoda, T.; Sato, M.; Kameda, A.

    1980-01-01

    An on-line diagnosis algorithm was developed and its verification test was performed using a minicomputer. This algorithm identifies the plant state by analyzing various system noise patterns, such as power spectral densities, coherence functions etc., in three procedure steps. Each obtained noise pattern is examined by using the distances from its reference patterns prepared for various plant states. Then, the plant state is identified by synthesizing each result with an evaluation weight. This weight is determined automatically from the reference noise patterns prior to on-line diagnosis. The test was performed with 50 MW (th) Steam Generator noise data recorded under various controller parameter values. The algorithm performance was evaluated based on a newly devised index. The results obtained with one kind of weight showed the algorithm efficiency under the proper selection of noise patterns. Results for another kind of weight showed the robustness of the algorithm to this selection. (orig.)

  7. On-line nuclear ash gauge for coal based on gamma-ray transmission techniques

    International Nuclear Information System (INIS)

    Rizk, R.A.M.; El-Kateb, A.H.; Abdul-Kader, A.M.

    1999-01-01

    Developments and applications of on-line nuclear gauges in the coal industry are highly requested. A nuclear ash gauge for coal, based on γ-ray transmission techniques is developed. Single and dual energy γ-ray beams are used to determine the ash content of coal. The percentage ash content as a function of the γ-ray intensities transmitted through coal samples is measured and sensitivity curves are obtained. An empirical formulation relating the ash content values to the γ-ray intensities is derived. Preliminary results show that both single and dual energy γ-ray transmission techniques can be used to give a rapid on-line estimation of the ash concentration values in coal with low cost and reasonable accuracy, but the dual one is much preferable. (author)

  8. Design of on-line steam generator leak monitoring system based on Cherenkov counting technique

    International Nuclear Information System (INIS)

    Dileep, B.N.; D'Cruz, S.J.; Biju, P.; Jashi, K.B.; Prabhakaran, V.; Venkataramana, K.; Managanvi, S.S.

    2006-01-01

    The methodology developed by Nuclear Power Corporation of India Ltd. for identification of leaky Steam Generator (SG) by monitoring 134 I activity in the blow down water is a very high sensitive method. However, this technique can not be put into use as an on-line system. A new method of on-line detection of SG leak and identify the offending SG based on Cherenkov counting technique is explained in this paper. It identifies the leak by detecting Cherenkov radiation produced by the hard beta emitting radio nuclides escaped into feed water during leak in an operating reactor. A simulated system shows that a leak rate of 2 kg/h can be detected by the proposed system, while coolant 134 I activity is 3.7 MBq/l (100μCi/l). (author)

  9. An improved, computer-based, on-line gamma monitor for plutonium anion exchange process control

    International Nuclear Information System (INIS)

    Pope, N.G.; Marsh, S.F.

    1987-06-01

    An improved, low-cost, computer-based system has replaced a previously developed on-line gamma monitor. Both instruments continuously profile uranium, plutonium, and americium in the nitrate anion exchange process used to recover and purify plutonium at the Los Alamos Plutonium Facility. The latest system incorporates a personal computer that provides full-feature multichannel analyzer (MCA) capabilities by means of a single-slot, plug-in integrated circuit board. In addition to controlling all MCA functions, the computer program continuously corrects for gain shift and performs all other data processing functions. This Plutonium Recovery Operations Gamma Ray Energy Spectrometer System (PROGRESS) provides on-line process operational data essential for efficient operation. By identifying abnormal conditions in real time, it allows operators to take corrective actions promptly. The decision-making capability of the computer will be of increasing value as we implement automated process-control functions in the future. 4 refs., 6 figs

  10. Multiband Slot-Based Dual Composite Right/Left-Handed Transmission Line

    Directory of Open Access Journals (Sweden)

    E. Abdo-Sanchez

    2012-10-01

    Full Text Available A dual Composite Right-/Left-Handed Transmission Line (CRLH TL implementation that presents multiband behaviour is proposed in this contribution. The artificial TL is realized by loading a host microstrip line with alternate rectangular stubs and slots. The required series and shunt immittances are respectively provided by the slot and the stub. Due to the distributed nature of these immittances, the resultant phase response presents theoretically infinite RH and LH alternate bands, thus being appropriate for multiband applications. The design methodology is described with the help of a proposed TLs-based equivalent circuit and highlights the simplicity for balance condition. Full wave simulated results of the dispersion characteristics and frequency response of a unit-cell and a three-cells structure are presented.

  11. Simulation-based comparisons of four apparel cell production modes of one clothing production line

    Directory of Open Access Journals (Sweden)

    Guoqiang Pan

    2014-10-01

    Full Text Available Purpose: This research, by using the SIMIO simulation platform, provides a quantitative and comparative analysis of how the efficiency of four different cell production modes is affected. It is hoped that the outcomes will be of some help for garment factories to optimize their production lines. Design/methodology/approach: The SIMIO simulation platform was employed in the research and comparisons were made of the simulation test results about the four different production modes. Findings: The operation mode, number of operators, and number of buffer areas are key factors affecting the production line efficiency, and need to be reasonably set to achieve the highest efficiency. Originality/value: As most research literature so far is qualitative, this research provided a simulation-based quantitative analysis of the production efficiency under different cell production modes.

  12. A study of the growth for the microalga Chlorella vulgaris by photo-bio-calorimetry and other on-line and off-line techniques

    NARCIS (Netherlands)

    Patino, R.; Janssen, M.G.J.; Stockar, von U.

    2007-01-01

    Calorimetry and other on-line techniques are used for the first time as complement to the traditional off-line methods in order to follow the growth of the green Chlorella vulgaris microalgae. A 2-L photo-bio-reactor was adapted from a commercial calorimeter used previously to study heterotrophic

  13. Path-integral and Ornstein-Zernike study of quantum fluid structures on the crystallization line

    International Nuclear Information System (INIS)

    Sesé, Luis M.

    2016-01-01

    Liquid neon, liquid para-hydrogen, and the quantum hard-sphere fluid are studied with path integral Monte Carlo simulations and the Ornstein-Zernike pair equation on their respective crystallization lines. The results cover the whole sets of structures in the r-space and the k-space and, for completeness, the internal energies, pressures and isothermal compressibilities. Comparison with experiment is made wherever possible, and the possibilities of establishing k-space criteria for quantum crystallization based on the path-integral centroids are discussed. In this regard, the results show that the centroid structure factor contains two significant parameters related to its main peak features (amplitude and shape) that can be useful to characterize freezing.

  14. Path-integral and Ornstein-Zernike study of quantum fluid structures on the crystallization line

    Energy Technology Data Exchange (ETDEWEB)

    Sesé, Luis M., E-mail: msese@ccia.uned.es [Departamento de Ciencias y Técnicas Fisicoquímicas, Universidad Nacional de Educación a Distancia, Paseo Senda del Rey 9, 28040 Madrid (Spain)

    2016-03-07

    Liquid neon, liquid para-hydrogen, and the quantum hard-sphere fluid are studied with path integral Monte Carlo simulations and the Ornstein-Zernike pair equation on their respective crystallization lines. The results cover the whole sets of structures in the r-space and the k-space and, for completeness, the internal energies, pressures and isothermal compressibilities. Comparison with experiment is made wherever possible, and the possibilities of establishing k-space criteria for quantum crystallization based on the path-integral centroids are discussed. In this regard, the results show that the centroid structure factor contains two significant parameters related to its main peak features (amplitude and shape) that can be useful to characterize freezing.

  15. Off-Line and Dynamic Production Scheduling – A Comparative Case Study

    Directory of Open Access Journals (Sweden)

    Bożek Andrzej

    2016-03-01

    Full Text Available A comprehensive case study of manufacturing scheduling solutions development is given. It includes highly generalized scheduling problem as well as a few scheduling modes, methods and problem models. The considered problem combines flexible job shop structure, lot streaming with variable sublots, transport times, setup times, and machine calendars. Tabu search metaheuristic and constraint programming methods have been used for the off-line scheduling. Two dynamic scheduling methods have also been implemented, i.e., dispatching rules for the completely reactive scheduling and a multi-agent system for the predictivereactive scheduling. In these implementations three distinct models of the problem have been used, based on: graph representation, optimal constraint satisfaction, and Petri net formalism. Each of these solutions has been verified in computational experiments. The results are compared and some findings about advantages, disadvantages, and suggestions on using the solutions are formulated.

  16. An improved DPSO with mutation based on similarity algorithm for optimization of transmission lines loading

    International Nuclear Information System (INIS)

    Shayeghi, H.; Mahdavi, M.; Bagheri, A.

    2010-01-01

    Static transmission network expansion planning (STNEP) problem acquires a principal role in power system planning and should be evaluated carefully. Up till now, various methods have been presented to solve the STNEP problem. But only in one of them, lines adequacy rate has been considered at the end of planning horizon and the problem has been optimized by discrete particle swarm optimization (DPSO). DPSO is a new population-based intelligence algorithm and exhibits good performance on solution of the large-scale, discrete and non-linear optimization problems like STNEP. However, during the running of the algorithm, the particles become more and more similar, and cluster into the best particle in the swarm, which make the swarm premature convergence around the local solution. In order to overcome these drawbacks and considering lines adequacy rate, in this paper, expansion planning has been implemented by merging lines loading parameter in the STNEP and inserting investment cost into the fitness function constraints using an improved DPSO algorithm. The proposed improved DPSO is a new conception, collectivity, which is based on similarity between the particle and the current global best particle in the swarm that can prevent the premature convergence of DPSO around the local solution. The proposed method has been tested on the Garver's network and a real transmission network in Iran, and compared with the DPSO based method for solution of the TNEP problem. The results show that the proposed improved DPSO based method by preventing the premature convergence is caused that with almost the same expansion costs, the network adequacy is increased considerably. Also, regarding the convergence curves of both methods, it can be seen that precision of the proposed algorithm for the solution of the STNEP problem is more than DPSO approach.

  17. Hexagonal Data Base Study.

    Science.gov (United States)

    1983-09-01

    Army position unless so designated by other authorized documents. The citation in this report of trade names of commzercially available products does...in this report. Two aspects 9’ • of the concept appeared to have been less than optimal. One was the trade off between batch and real-time...suggested in section 4.1.2. Recode the new concept and compare the results with the present work. I b. Intergrate point and line data into the

  18. Integrating Multiple On-line Knowledge Bases for Disease-Lab Test Relation Extraction.

    Science.gov (United States)

    Zhang, Yaoyun; Soysal, Ergin; Moon, Sungrim; Wang, Jingqi; Tao, Cui; Xu, Hua

    2015-01-01

    A computable knowledge base containing relations between diseases and lab tests would be a great resource for many biomedical informatics applications. This paper describes our initial step towards establishing a comprehensive knowledge base of disease and lab tests relations utilizing three public on-line resources. LabTestsOnline, MedlinePlus and Wikipedia are integrated to create a freely available, computable disease-lab test knowledgebase. Disease and lab test concepts are identified using MetaMap and relations between diseases and lab tests are determined based on source-specific rules. Experimental results demonstrate a high precision for relation extraction, with Wikipedia achieving the highest precision of 87%. Combining the three sources reached a recall of 51.40%, when compared with a subset of disease-lab test relations extracted from a reference book. Moreover, we found additional disease-lab test relations from on-line resources, indicating they are complementary to existing reference books for building a comprehensive disease and lab test relation knowledge base.

  19. A determination of occlusal plane comparing different levels of the tragus to form ala-tragal line or Camper's line: A photographic study.

    Science.gov (United States)

    Kumar, Sandeep; Garg, Sandeep; Gupta, Seema

    2013-02-01

    The purpose of this study was to determine accurately the part of the tragus to be used to form the Ala-Tragal line or Camper's line in orthognathic profile patients. 150 dentate subjects with age of 18-40 years with orthognathic profile were sampled. Life-size lateral digital photographs of the face with fox plane were taken in natural head position. Different angles between Eye-Ear plane and occlusal plane (OT1-OP), Eye-Ear plane and ala-superior border of tragus (OT1-AT1), Eye-Ear plane and ala-middle border of tragus (OT1-AT2) and Eye-Ear plane and ala-inferior border of tragus (OT1-AT3) were calculated using computer software package, AutoCAD 2004. From the three angles formed by the Eye-ear plane (OT1 or FH plane) and the ala-tragal lines, the one closest to the angle formed between Eye-Ear plane (OT1) and occlusal plane (OP) was used to determine the occlusal plane of orientation. The obtained results were subjected to ANOVA F test, Tukey's Honestly significant difference test, followed by Karl Pearson coefficient of correlation test. P values of less than 0.05 were taken as statistically significant. The mean of base line angle i.e. OT1-OP angle (11.96 ± 4.36) was found to be close to OT1-AT2 angle (13.67 ± 1.93) and OT1-AT3 angle (10.31 ± 2.03), but OT1-OP angle was found to be more closer to OT1-AT3 angle. Comparison of mean angles showed that OT1-OP angle in both males (11.68) and females (12.51) is close to OT1-AT3 angle (males- 11.01, females- 11.95). The line joining from ala to the lower border of the tragus was parallel to the occlusal plane in 53.3% of the subjects. There was no influence of the sex on the level of occlusal plane.

  20. Theoretical and experimental study of microstrip-to-slot line uniplanar transition

    Science.gov (United States)

    Yook, Jong-Gwan; Dib, Nihad I.; Katehi, Linda P. B.; Simons, Rainee N.; Taub, Susan R.

    1994-05-01

    Recent advances in MMCI technology make it possible to construct transitions from CPW-to-microstrip with via hole, microstrip-to-slot line and microshield line-to-CPW all of which have potential applications in the feed network of antennas. In this study we investigate the characteristics of the microstrip-to-slot line uniplanar transition using the finite element methods (FEM) and finite difference time domain (FDTD) techniques, and compared the theoretical results with the measurements. In both cases, the results agree with the measurements within a few percent.

  1. Can the waiting-point nucleus 78Ni be studied at an on-line mass-separator?

    Science.gov (United States)

    Wöhr, A.; Andreyev, A.; Bijnens, N.; Breitenbach, J.; Franchoo, S.; Huyse, M.; Kudryavtsev, Y. A.; Piechaczek, A.; Raabe, R. R.; Reusen, I.; Vermeeren, L.; Van Duppen, P.

    1997-02-01

    Short-lived nickel isotopes have been studied using a chemically selective Ion Guide Laser Ion Source (IGLIS) based on resonance ionisation of atoms at the Leuven Isotope Separator On-Line (LISOL) separator. The decay properties of different Ni isotopes have been studied using β-γ-coincidences. Experimental production rates of proton induced fission of 238U are obtained for 69,71Ni. These numbers are in a strong disagreement with Silberg-Tsao calculations.

  2. Case Reports of Idiopathic Thrombocytopenia Unresponsive to First-Line Therapies Treated With Traditional Herbal Medicines Based on Syndrome Differentiation.

    Science.gov (United States)

    Yang, Juno; Lee, Beom-Joon; Lee, Jun-Hwan

    The objective of our study is to present two cases showing the effects of traditional Korean herbal medicines based on traditional Korean medicine (TKM) for the treatment of immune thrombocytopenic purpura (ITP). One patient showed no response to treatment with steroids and an immunosuppressive agent. Moreover, liver toxicity and side effects of steroids were evident. However, after he ceased conventional treatment and started to take an herbal medicine, his liver function normalized and the steroid side effects resolved. Ultimately, he achieved complete remission. Another patient with ITP had sustained remission after steroid therapy in childhood, but extensive uterine bleeding and thrombocytopenia recurred when she was 16 years old. She was managed with steroids again for 2 years, but severe side effects occurred, and eventually she ceased taking steroids. She refused a splenectomy, and was then treated with a herbal medicine for 7 months, ultimately leading to sustained remission again. Many patients with resistance to first-line treatments tend to be reluctant to undergo a splenectomy, considered a standard second-line treatment. In conclusion, herbal medicines, based on TKM, may offer alternative treatments for persistent or chronic ITP that is resistant to existing first-line treatments. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. An analysis of line-drawings based upon automatically inferred grammar and its application to chest x-ray images

    International Nuclear Information System (INIS)

    Nakayama, Akira; Yoshida, Yuuji; Fukumura, Teruo

    1984-01-01

    There is a technique using inferring grammer as image- structure analyzing technique. This technique involves a few problems if it is applied to naturally obtained images, as the practical grammatical technique for two-dimensional image is not established. The authors developed a technique which solved the above problems for the main purpose of the automated structure analysis of naturally obtained image. The first half of this paper describes on the automatic inference of line drawing generation grammar and the line drawing analysis based on that automatic inference. The second half of the paper reports on the actual analysis. The proposed technique is that to extract object line drawings out of the line drawings containing noise. The technique was evaluated for its effectiveness with an example of extracting rib center lines out of thin line chest X-ray images having practical scale and complexity. In this example, the total number of characteristic points (ends, branch points and intersections) composing line drawings per one image was 377, and the total number of line segments composing line drawings was 566 on average per sheet. The extraction ratio was 86.6 % which seemed to be proper when the complexity of input line drawings was considered. Further, the result was compared with the identified rib center lines with the automatic screening system AISCR-V3 for comparison with the conventional processing technique, and it was satisfactory when the versatility of this method was considered. (Wakatsuki, Y.)

  4. Parallel Hough Transform-Based Straight Line Detection and Its FPGA Implementation in Embedded Vision

    Directory of Open Access Journals (Sweden)

    Nam Ling

    2013-07-01

    Full Text Available Hough Transform has been widely used for straight line detection in low-definition and still images, but it suffers from execution time and resource requirements. Field Programmable Gate Arrays (FPGA provide a competitive alternative for hardware acceleration to reap tremendous computing performance. In this paper, we propose a novel parallel Hough Transform (PHT and FPGA architecture-associated framework for real-time straight line detection in high-definition videos. A resource-optimized Canny edge detection method with enhanced non-maximum suppression conditions is presented to suppress most possible false edges and obtain more accurate candidate edge pixels for subsequent accelerated computation. Then, a novel PHT algorithm exploiting spatial angle-level parallelism is proposed to upgrade computational accuracy by improving the minimum computational step. Moreover, the FPGA based multi-level pipelined PHT architecture optimized by spatial parallelism ensures real-time computation for 1,024 × 768 resolution videos without any off-chip memory consumption. This framework is evaluated on ALTERA DE2-115 FPGA evaluation platform at a maximum frequency of 200 MHz, and it can calculate straight line parameters in 15.59 ms on the average for one frame. Qualitative and quantitative evaluation results have validated the system performance regarding data throughput, memory bandwidth, resource, speed and robustness.

  5. A Pilot Directional Protection for HVDC Transmission Line Based on Relative Entropy of Wavelet Energy

    Directory of Open Access Journals (Sweden)

    Sheng Lin

    2015-07-01

    Full Text Available On the basis of analyzing high-voltage direct current (HVDC transmission system and its fault superimposed circuit, the direction of the fault components of the voltage and the current measured at one end of transmission line is certified to be different for internal faults and external faults. As an estimate of the differences between two signals, relative entropy is an effective parameter for recognizing transient signals in HVDC transmission lines. In this paper, the relative entropy of wavelet energy is applied to distinguish internal fault from external fault. For internal faults, the directions of fault components of voltage and current are opposite at the two ends of the transmission line, indicating a huge difference of wavelet energy relative entropy; for external faults, the directions are identical, indicating a small difference. The simulation results based on PSCAD/EMTDC show that the proposed pilot protection system acts accurately for faults under different conditions, and its performance is not affected by fault type, fault location, fault resistance and noise.

  6. Finite Element Based Response Surface Methodology to Optimize Segmental Tunnel Lining

    Directory of Open Access Journals (Sweden)

    A. Rastbood

    2017-04-01

    Full Text Available The main objective of this paper is to optimize the geometrical and engineering characteristics of concrete segments of tunnel lining using Finite Element (FE based Response Surface Methodology (RSM. Input data for RSM statistical analysis were obtained using FEM. In RSM analysis, thickness (t and elasticity modulus of concrete segments (E, tunnel height (H, horizontal to vertical stress ratio (K and position of key segment in tunnel lining ring (θ were considered as input independent variables. Maximum values of Mises and Tresca stresses and tunnel ring displacement (UMAX were set as responses. Analysis of variance (ANOVA was carried out to investigate the influence of each input variable on the responses. Second-order polynomial equations in terms of influencing input variables were obtained for each response. It was found that elasticity modulus and key segment position variables were not included in yield stresses and ring displacement equations, and only tunnel height and stress ratio variables were included in ring displacement equation. Finally optimization analysis of tunnel lining ring was performed. Due to absence of elasticity modulus and key segment position variables in equations, their values were kept to average level and other variables were floated in related ranges. Response parameters were set to minimum. It was concluded that to obtain optimum values for responses, ring thickness and tunnel height must be near to their maximum and minimum values, respectively and ground state must be similar to hydrostatic conditions.

  7. Parallel Hough Transform-based straight line detection and its FPGA implementation in embedded vision.

    Science.gov (United States)

    Lu, Xiaofeng; Song, Li; Shen, Sumin; He, Kang; Yu, Songyu; Ling, Nam

    2013-07-17

    Hough Transform has been widely used for straight line detection in low-definition and still images, but it suffers from execution time and resource requirements. Field Programmable Gate Arrays (FPGA) provide a competitive alternative for hardware acceleration to reap tremendous computing performance. In this paper, we propose a novel parallel Hough Transform (PHT) and FPGA architecture-associated framework for real-time straight line detection in high-definition videos. A resource-optimized Canny edge detection method with enhanced non-maximum suppression conditions is presented to suppress most possible false edges and obtain more accurate candidate edge pixels for subsequent accelerated computation. Then, a novel PHT algorithm exploiting spatial angle-level parallelism is proposed to upgrade computational accuracy by improving the minimum computational step. Moreover, the FPGA based multi-level pipelined PHT architecture optimized by spatial parallelism ensures real-time computation for 1,024 × 768 resolution videos without any off-chip memory consumption. This framework is evaluated on ALTERA DE2-115 FPGA evaluation platform at a maximum frequency of 200 MHz, and it can calculate straight line parameters in 15.59 ms on the average for one frame. Qualitative and quantitative evaluation results have validated the system performance regarding data throughput, memory bandwidth, resource, speed and robustness.

  8. A new image reconstruction method for 3-D PET based upon pairs of near-missing lines of response

    Energy Technology Data Exchange (ETDEWEB)

    Kawatsu, Shoji [Department of Radiology, Kyoritu General Hospital, 4-33 Go-bancho, Atsuta-ku, Nagoya-shi, Aichi 456-8611 (Japan) and Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, 36-3, Gengo Moriaka-cho, Obu-shi, Aichi 474-8522 (Japan)]. E-mail: b6rgw@fantasy.plala.or.jp; Ushiroya, Noboru [Department of General Education, Wakayama National College of Technology, 77 Noshima, Nada-cho, Gobo-shi, Wakayama 644-0023 (Japan)

    2007-02-01

    We formerly introduced a new image reconstruction method for three-dimensional positron emission tomography, which is based upon pairs of near-missing lines of response. This method uses an elementary geometric property of lines of response, namely that two lines of response which originate from radioactive isotopes located within a sufficiently small voxel, will lie within a few millimeters of each other. The effectiveness of this method was verified by performing a simulation using GATE software and a digital Hoffman phantom.

  9. Calibration and Limitations of the Mg II Line-based Black Hole Masses

    Science.gov (United States)

    Woo, Jong-Hak; Le, Huynh Anh N.; Karouzos, Marios; Park, Dawoo; Park, Daeseong; Malkan, Matthew A.; Treu, Tommaso; Bennert, Vardha N.

    2018-06-01

    We present single-epoch black hole mass ({M}BH}) calibrations based on the rest-frame ultraviolet (UV) and optical measurements of Mg II 2798 Å and Hβ 4861 Å lines and the active galactic nucleus (AGN) continuum, using a sample of 52 moderate-luminosity AGNs at z ∼ 0.4 and z ∼ 0.6 with high-quality Keck spectra. We combine this sample with a large number of luminous AGNs from the Sloan Digital Sky Survey to increase the dynamic range for a better comparison of UV and optical velocity and luminosity measurements. With respect to the reference {M}BH} based on the line dispersion of Hβ and continuum luminosity at 5100 Å, we calibrate the UV and optical mass estimators by determining the best-fit values of the coefficients in the mass equation. By investigating whether the UV estimators show a systematic trend with Eddington ratio, FWHM of Hβ, Fe II strength, or UV/optical slope, we find no significant bias except for the slope. By fitting the systematic difference of Mg II-based and Hβ-based masses with the L 3000/L 5100 ratio, we provide a correction term as a function of the spectral index as ΔC = 0.24 (1 + α λ ) + 0.17, which can be added to the Mg II-based mass estimators if the spectral slope can be well determined. The derived UV mass estimators typically show >∼0.2 dex intrinsic scatter with respect to the Hβ-based {M}BH}, suggesting that the UV-based mass has an additional uncertainty of ∼0.2 dex, even if high-quality rest-frame UV spectra are available.

  10. High frequency study of a short niobium/lead alloy line

    International Nuclear Information System (INIS)

    Mazuer, J.; Gilchrist, J.

    1974-01-01

    The resonant Q-factors of coaxial lines 1.42 m in length, consisting of fine niobium wires in superconducting tubes, have been studied. The lines are either open-circuited at each end or else short-circuited at each end. In either case the fundamental resonance and odd harmonics up to the ninth were observed. Various surface treatments of the wire made no appreciable difference to the Q value of the open-circuited lines. The short-circuited lines had much lower Q values due to imperfect short-circuiting contacts, and were used mainly to study the effect of a superposed direct current. This was appreciable even when the current was much smaller than the current that the wire would support without resistive transition. The additional high-frequency loss caused by the current was attributed to flux penetration. (author)

  11. Numerical study of whisker field lines in the periphery of the Large Helical Device

    International Nuclear Information System (INIS)

    Akao, Hideki

    1990-01-01

    The behavior of periphery magnetic field lines in the standard Large-Helical Device (l=2 heliotron/torsatron type) configuration is studied numerically. Three different types of behavior are found, corresponding to three different regions: the stochastic region near the outermost magnetic surface, the whisker region, and the inter-whisker region outside the stochastic region. The behavior of whisker and inter-whisker field lines is specifically analyzed. It is found that whisker field lines exhibit both regular and irregular types of behavior, whereas inter-whisker field lines exhibit only regular behavior. The connection lengths for the whisker field lines are usually as long as several tens of toroidal pitches, whereas those for the inter-whisker field lines are usually less than ten toroidal pitch lengths. Whisker field lines are characterized by three fundamental processes; stretching, folding, and nesting associated with the motion of a residual X-point of the separatrix. Simple modeling is performed to reproduce these three fundamental processes. (author)

  12. Study of Yield and Effective Traits in Bread Wheat Recombinant Inbred Lines (Triticum aestivum L. under Water Deficit Condition

    Directory of Open Access Journals (Sweden)

    S. Mohammad zadeh

    2013-11-01

    Full Text Available The effects some traits on seed yield of recombinant inbred lines of wheat under water deficit stress was studied. This research was done at the Agricultural Research Stations, Islamic Azad University, Tabriz Branch in 2010- 2011. 28 recombinant inbred lines of wheat bread with two parents (Norstar and Zagros in split plot experiment based on a randomized complete block design with three replications at two irrigation levels (70 and 140 mm evaporation from pan class A were studied. Analysis of variance indicated a significant genetic differences in all traits under study among the lines. Lines No. 32, 163 and 182 produced highest yield under both irrigation levels. Number of spikes, grains per spike and harvest index had the highest positive correlation with grain yield. Path analysis based on stepwise regression showed that under the normal irrigation conditions, number spike (0.556, number of grains per spike (0.278, weight of 1000 grain (0.259 and the drought stress number spike (0.430, straw yield (0.276 and peduncle length (0.323 had the most direct and positive effect on yield respectively.

  13. The peculiar A star HD 110066: a photographic region line identification study

    International Nuclear Information System (INIS)

    Adelman, S.J.

    1988-01-01

    A line identification study of the very sharp-lined peculiar A star HD 110066 has been performed using four high dispersion photographic region spectrograms. New species found include Al I, Si I, S II, Ti I, Co II, Zr II, Cd I, La II, Ce III, Gd III, Dy II, Er II and Tm II. The presence of these species is in accord with the continuity of the magnetic Ap star sequence. (author)

  14. Radionuclide scanning after total knee replacement: correlation with pain and radiolucent lines. A prospective study

    DEFF Research Database (Denmark)

    Duus, B R; Boeckstyns, M; Kjaer, L

    1987-01-01

    The authors examined the relationships among Tc-99m radionuclide bone scan findings, pain, and radiolucent lines in 35 postsurgical knees. Our prospective study included bone scans, as well as radiographic and clinical examination three, seven, and 12 months after knee replacement surgery in 35...... and nonpainful knees, and the degree of isotope uptake did not correlate with the development of radiolucent lines around the prosthetic components....

  15. Fate of third molar in line of mandibular angle fracture - Retrospective study

    Directory of Open Access Journals (Sweden)

    Preetha Balaji

    2015-01-01

    Conclusion: The present study fails to identify any concrete factors that would predict the failure of the retained third molar that were involved in the line of mandibular fractures. The proof presented here, especially with low complication rates indicate that all impacted third molar along the line of fracture be removed and unless necessary, the partially erupted teeth would also be extracted. In such a situation, the rate of infection and survival of the third molar would have been entirely different.

  16. Predictions of On-Line Banks' Fraudulent: A Study on Discriminant Analysis.

    OpenAIRE

    Gabriel Joseph Mukungu; Gwangyong Gim

    2014-01-01

    The information and communication technology (ICT) is growing fast in the community along with some risks. The on-line banks' fraudulent are increasing dramatically resulting in the loss of money and retardate the growth on economic development. Some law enforcers like Tanzanian police yet use the traditional prevention technologies to investigate these on-line banks' fraudulent cases mainly known as cyber crimes. For the purpose of this study, 150 data were collected as cyber...

  17. Analytical study for the ability of nonlinear transmission lines to generate solitons

    International Nuclear Information System (INIS)

    Mostafa, S.I.

    2009-01-01

    The ability of the nonlinear transmission lines (NLTL) has been studied analytically, in this paper to generate solitons and to cause waveform spreading. This can be achieved by balancing nonlinearity and dispersion. A new technique of improved tanh method (ITM) and improved sech methods (ISM) is applied to the nonlinear partial differential equation that describes the NLTL. It is found that the parameters of the transmission line play an important role in controlling the shape of the soliton.

  18. A Rapid Coordinate Transformation Method Applied in Industrial Robot Calibration Based on Characteristic Line Coincidence

    Science.gov (United States)

    Liu, Bailing; Zhang, Fumin; Qu, Xinghua; Shi, Xiaojia

    2016-01-01

    Coordinate transformation plays an indispensable role in industrial measurements, including photogrammetry, geodesy, laser 3-D measurement and robotics. The widely applied methods of coordinate transformation are generally based on solving the equations of point clouds. Despite the high accuracy, this might result in no solution due to the use of ill conditioned matrices. In this paper, a novel coordinate transformation method is proposed, not based on the equation solution but based on the geometric transformation. We construct characteristic lines to represent the coordinate systems. According to the space geometry relation, the characteristic line scan is made to coincide by a series of rotations and translations. The transformation matrix can be obtained using matrix transformation theory. Experiments are designed to compare the proposed method with other methods. The results show that the proposed method has the same high accuracy, but the operation is more convenient and flexible. A multi-sensor combined measurement system is also presented to improve the position accuracy of a robot with the calibration of the robot kinematic parameters. Experimental verification shows that the position accuracy of robot manipulator is improved by 45.8% with the proposed method and robot calibration. PMID:26901203

  19. A Rapid Coordinate Transformation Method Applied in Industrial Robot Calibration Based on Characteristic Line Coincidence

    Directory of Open Access Journals (Sweden)

    Bailing Liu

    2016-02-01

    Full Text Available Coordinate transformation plays an indispensable role in industrial measurements, including photogrammetry, geodesy, laser 3-D measurement and robotics. The widely applied methods of coordinate transformation are generally based on solving the equations of point clouds. Despite the high accuracy, this might result in no solution due to the use of ill conditioned matrices. In this paper, a novel coordinate transformation method is proposed, not based on the equation solution but based on the geometric transformation. We construct characteristic lines to represent the coordinate systems. According to the space geometry relation, the characteristic line scan is made to coincide by a series of rotations and translations. The transformation matrix can be obtained using matrix transformation theory. Experiments are designed to compare the proposed method with other methods. The results show that the proposed method has the same high accuracy, but the operation is more convenient and flexible. A multi-sensor combined measurement system is also presented to improve the position accuracy of a robot with the calibration of the robot kinematic parameters. Experimental verification shows that the position accuracy of robot manipulator is improved by 45.8% with the proposed method and robot calibration.

  20. Differential BPFs with Multiple Transmission Zeros Based on Terminated Coupled Lines

    Science.gov (United States)

    Niu, Yiming; Yang, Guo; Wu, Wen

    2018-04-01

    Differential bandpass filters (BPFs) named Filter A and Filter B based on Terminated Coupled Lines (TCLs) are proposed in this letter. The TCLs contributes to not only three poles in differential-mode (DM) for wideband filtering response but also multiple zeros in both DM and common-mode (CM) offering wide DM out-of-band rejection and good CM suppression. Fabricated filters centred at 3.5 GHz with wide DM passband and wideband CM suppression have been designed and measured. The filters improved the noise suppression capability of the communication and radiometer systems. The simulated and measured results are in good agreement.

  1. The Design of a Molecular Assembly Line Based on Biological Molecules

    Science.gov (United States)

    2003-06-01

    parenthesis in figure 1.8 is a bi-stable toggle switch. Introduction: Molecular assembly lines O=P-O- O O HOH H0P-0- O -O- 4 Polymerase HO H--- O HHO ...sample. Therefore, the samples are self-consistent. From here on, the calculated temperature based on FAM emission MNSowmm" RF Biology: Results and...irradiation for one hour. Figure 2.11 shows the fluorescence spectra of FAM emission (4 scans averaged over 200 seconds) in a 300MHz field. The increased

  2. On-line control system for electron injector based on autoemission cathode

    International Nuclear Information System (INIS)

    Egorov, N.V.; Karpov, A.G.; Ovsyannikov, D.A.; Prudnikov, A.P.

    1987-01-01

    An original on-line system of control of electron injector parameters on the base of an autoemission cathode is described. The system includes hardware (analog-to-digital and graphical displays, a printer, a magnetic disc memory a plotter) and data control and readout equipment. A high-voltage power source of the 'RACE' is controlled by digital measuring devices connected with a computer data via a special matching device. Software includes servicing subroutines for injector controls and those permitting to display, plot and print results. The main operating program functioning in the interactive mode enables to specify the injector operating conditions and check its characteristics

  3. Transcriptome-wide studies of prostate cancer cell lines in the context of medical radiation

    International Nuclear Information System (INIS)

    Hammer, Paul

    2012-01-01

    The use of radiotherapy in addition to chemotherapy and surgical removal is the most powerful instrument in the fight against malignant tumors in cancer medicine. After cardiovascular diseases, cancer is the second leading cause of death in the western world, in which prostate cancer is the most frequent male cancer. Despite continuous technological improvements in radiological instruments and prognosis, it may occur a recurrence up to many years after radiotherapy due to a high resistance capability of individual malignant cells of the locally occurring tumor. Although modern radiation biology has studied many aspects of the resistance mechanisms, questions are largely unanswered especially in regards to prognostic terms and time response of tumor cells to ionizing radiation. As cellular models four prostate cancer cell lines with different radiation sensitivities (PC3, DuCaP, DU-145, RWPE-1) were cultured and tested for their ability to survive after exposure to ionizing radiation by a trypane blue and MTT viability assay. The proliferative capacity of the four cell lines was determined using a colony formation assay. The PC3 cell line (radiation-resistant) and the DuCaP cell line (radiation-sensitive) showed the maximal differences in terms of radiation sensitivity. Based on these results the two cell lines were selected to allow identification of potential prognostic marker for predicting the effectiveness of radiation therapy via their transcriptome-wide gene expression. Furthermore, a time series experiment with the radiation-resistant PC3 cell line was performed. At 8 different time points, during the period from 00:00 - 42:53 (hh:mm) after exposure with 1 Gy, the mRNA was quantified by next generation sequencing to investigate the dynamic behavior of time-delayed gene expression and to discover resistance mechanisms. Of 10,966 expressed genes 730 were significant differentially expressed, determined by setting a fold change threshold in conjunction with a P

  4. Effects of Goal Line Feedback on Level, Slope, and Stability of Performance within Curriculum-Based Measurement.

    Science.gov (United States)

    Fuchs, Lynn S.; And Others

    1991-01-01

    Nineteen special educators implemented Curriculum-Based Measurement with a total of 36 learning-disabled math pupils in grades 2-8 to examine the effects of goal line feedback. Results indicated comparable levels and slopes of student performance across treatment conditions, although goal line feedback was associated with greater performance…

  5. Analysis of the cytotoxicity of carbon-based nanoparticles, diamond and graphite, in human glioblastoma and hepatoma cell lines

    DEFF Research Database (Denmark)

    Zakrzewska, Karolina Ewa; Samluk, Anna; Wierzbicki, Mateusz

    2015-01-01

    carbon based nanoparticles, diamond and graphite, on glioblastoma and hepatoma cells were compared. First, we confirmed previous results that diamond nanoparticles are practically nontoxic. Second, graphite nanoparticles exhibited a negative impact on glioblastoma, but not on hepatoma cells. The studied...... carbon nanoparticles could be a potentially useful tool for therapeutics delivery to the brain tissue with minimal side effects on the hepatocytes. Furthermore, we showed the influence of the nanoparticles on the stable, fluorescently labeled tumor cell lines and concluded that the labeled cells...

  6. Deep Learning Based Solar Flare Forecasting Model. I. Results for Line-of-sight Magnetograms

    Science.gov (United States)

    Huang, Xin; Wang, Huaning; Xu, Long; Liu, Jinfu; Li, Rong; Dai, Xinghua

    2018-03-01

    Solar flares originate from the release of the energy stored in the magnetic field of solar active regions, the triggering mechanism for these flares, however, remains unknown. For this reason, the conventional solar flare forecast is essentially based on the statistic relationship between solar flares and measures extracted from observational data. In the current work, the deep learning method is applied to set up the solar flare forecasting model, in which forecasting patterns can be learned from line-of-sight magnetograms of solar active regions. In order to obtain a large amount of observational data to train the forecasting model and test its performance, a data set is created from line-of-sight magnetogarms of active regions observed by SOHO/MDI and SDO/HMI from 1996 April to 2015 October and corresponding soft X-ray solar flares observed by GOES. The testing results of the forecasting model indicate that (1) the forecasting patterns can be automatically reached with the MDI data and they can also be applied to the HMI data; furthermore, these forecasting patterns are robust to the noise in the observational data; (2) the performance of the deep learning forecasting model is not sensitive to the given forecasting periods (6, 12, 24, or 48 hr); (3) the performance of the proposed forecasting model is comparable to that of the state-of-the-art flare forecasting models, even if the duration of the total magnetograms continuously spans 19.5 years. Case analyses demonstrate that the deep learning based solar flare forecasting model pays attention to areas with the magnetic polarity-inversion line or the strong magnetic field in magnetograms of active regions.

  7. Integrated QSAR study for inhibitors of Hedgehog Signal Pathway against multiple cell lines:a collaborative filtering method.

    Science.gov (United States)

    Gao, Jun; Che, Dongsheng; Zheng, Vincent W; Zhu, Ruixin; Liu, Qi

    2012-07-31

    The Hedgehog Signaling Pathway is one of signaling pathways that are very important to embryonic development. The participation of inhibitors in the Hedgehog Signal Pathway can control cell growth and death, and searching novel inhibitors to the functioning of the pathway are in a great demand. As the matter of fact, effective inhibitors could provide efficient therapies for a wide range of malignancies, and targeting such pathway in cells represents a promising new paradigm for cell growth and death control. Current research mainly focuses on the syntheses of the inhibitors of cyclopamine derivatives, which bind specifically to the Smo protein, and can be used for cancer therapy. While quantitatively structure-activity relationship (QSAR) studies have been performed for these compounds among different cell lines, none of them have achieved acceptable results in the prediction of activity values of new compounds. In this study, we proposed a novel collaborative QSAR model for inhibitors of the Hedgehog Signaling Pathway by integration the information from multiple cell lines. Such a model is expected to substantially improve the QSAR ability from single cell lines, and provide useful clues in developing clinically effective inhibitors and modifications of parent lead compounds for target on the Hedgehog Signaling Pathway. In this study, we have presented: (1) a collaborative QSAR model, which is used to integrate information among multiple cell lines to boost the QSAR results, rather than only a single cell line QSAR modeling. Our experiments have shown that the performance of our model is significantly better than single cell line QSAR methods; and (2) an efficient feature selection strategy under such collaborative environment, which can derive the commonly important features related to the entire given cell lines, while simultaneously showing their specific contributions to a specific cell-line. Based on feature selection results, we have proposed several

  8. Adaptive control based on an on-line parameter estimation of an upper limb exoskeleton.

    Science.gov (United States)

    Riani, Akram; Madani, Tarek; Hadri, Abdelhafid El; Benallegue, Abdelaziz

    2017-07-01

    This paper presents an adaptive control strategy for an upper-limb exoskeleton based on an on-line dynamic parameter estimator. The objective is to improve the control performance of this system that plays a critical role in assisting patients for shoulder, elbow and wrist joint movements. In general, the dynamic parameters of the human limb are unknown and differ from a person to another, which degrade the performances of the exoskeleton-human control system. For this reason, the proposed control scheme contains a supplementary loop based on a new efficient on-line estimator of the dynamic parameters. Indeed, the latter is acting upon the parameter adaptation of the controller to ensure the performances of the system in the presence of parameter uncertainties and perturbations. The exoskeleton used in this work is presented and a physical model of the exoskeleton interacting with a 7 Degree of Freedom (DoF) upper limb model is generated using the SimMechanics library of MatLab/Simulink. To illustrate the effectiveness of the proposed approach, an example of passive rehabilitation movements is performed using multi-body dynamic simulation. The aims is to maneuver the exoskeleton that drive the upper limb to track desired trajectories in the case of the passive arm movements.

  9. Antimutagenic, Antirecombinogenic, and Antitumor Effect of Amygdalin in a Yeast Cell-Based Test and Mammalian Cell Lines.

    Science.gov (United States)

    Todorova, Atanaska; Pesheva, Margarita; Iliev, Ivan; Bardarov, Krum; Todorova, Teodora

    2017-04-01

    Amygdalin is a major component of the seeds of Rosaceae family of plants such as apricots, peaches, cherry, nectarines, apples, plums, and so on, as well as almonds. It is used in alternative medicine for cancer prevention, alleviation of fever, cough suppression, and quenching thirst. The aim of the present study is to determine the mutagenic and recombinogenic effects of amygdalin in a test system Saccharomyces cerevisiae and to evaluate its potential antitumor effect in a yeast cell-based test and colon cancer cell lines. Results obtained show that concentrations 25, 50, and 100 μg/mL did not have any cytotoxic, mutagenic, and carcinogenic effect in yeast cell-based tests. Pretreatment with amygdalin at concentration 100 μg/mL leads to around twofold of the cell survival and decrease of reverse mutation frequency, induced by the alkylating agent methyl methanesulfonate. The frequency of gene conversion and mitotic crossing-over is around threefold lower. The anticarcinogenic potential of amygdalin at the same concentration is presented as around fourfold reduction of Ty1 retrotransposition induced by hexavalent chromium. In summary, data presented in this study provide evidence concerning the inability of amygdalin itself to provoke events related to the initial steps of tumorigenesis. In addition, the observed antimutagenic/antirecombinogenic effect could be activation of error-free and error-prone recombination events. Based on the high selectivity toward normal or tumor cell lines, it could be speculated that amygdalin has higher cytotoxic effect in cell lines with higher proliferative and metabolic activity, which are the majority of fast developing tumors.

  10. Performance evaluation of a lossy transmission lines based diode detector at cryogenic temperature.

    Science.gov (United States)

    Villa, E; Aja, B; de la Fuente, L; Artal, E

    2016-01-01

    This work is focused on the design, fabrication, and performance analysis of a square-law Schottky diode detector based on lossy transmission lines working under cryogenic temperature (15 K). The design analysis of a microwave detector, based on a planar gallium-arsenide low effective Schottky barrier height diode, is reported, which is aimed for achieving large input return loss as well as flat sensitivity versus frequency. The designed circuit demonstrates good sensitivity, as well as a good return loss in a wide bandwidth at Ka-band, at both room (300 K) and cryogenic (15 K) temperatures. A good sensitivity of 1000 mV/mW and input return loss better than 12 dB have been achieved when it works as a zero-bias Schottky diode detector at room temperature, increasing the sensitivity up to a minimum of 2200 mV/mW, with the need of a DC bias current, at cryogenic temperature.

  11. In-line photonic microcells based on the elliptical microfibers for refractive index sensors applications

    Science.gov (United States)

    Jin, Wa; Liu, Xuejing; Jin, Wei

    2017-10-01

    We report the fabrication of in-line photonic microcells (PMCs) by encapsulating tapered elliptical microfibers (MFs) inside glass tubes. The encapsulation does not change the optical property of the MF but protects the elliptical MF from external disturbance and contamination and makes the micro-laboratory robust. Such micro-laboratory can be easily integrated into standard fiber-optic circuits with low loss, making the elliptical MF-based devices more practical for real-world applications. Evanescent field sensing is realized by fabricating micro-channel on the PMC for ingress/egress of sample liquids/gas. Based on the encapsulated elliptical MF PMCs, we demonstrated RI sensitivity of 2024 nm per refractive index unit (nm/RIU) in gaseous environment and 21231 nm/RIU in water.

  12. Line-scanning confocal microscopy for high-resolution imaging of upconverting rare-earth-based contrast agents

    Science.gov (United States)

    Higgins, Laura M.; Zevon, Margot; Ganapathy, Vidya; Sheng, Yang; Tan, Mei Chee; Riman, Richard E.; Roth, Charles M.; Moghe, Prabhas V.; Pierce, Mark C.

    2015-01-01

    Abstract. Rare-earth (RE) doped nanocomposites emit visible luminescence when illuminated with continuous wave near-infrared light, making them appealing candidates for use as contrast agents in biomedical imaging. However, the emission lifetime of these materials is much longer than the pixel dwell times used in scanning intravital microscopy. To overcome this limitation, we have developed a line-scanning confocal microscope for high-resolution, optically sectioned imaging of samples labeled with RE-based nanomaterials. Instrument performance is quantified using calibrated test objects. NaYF4:Er,Yb nanocomposites are imaged in vitro, and in ex vivo tissue specimens, with direct comparison to point-scanning confocal microscopy. We demonstrate that the extended pixel dwell time of line-scanning confocal microscopy enables subcellular-level imaging of these nanomaterials while maintaining optical sectioning. The line-scanning approach thus enables microscopic imaging of this emerging class of contrast agents for preclinical studies, with the potential to be adapted for real-time in vivo imaging in the clinic. PMID:26603495

  13. R and D study on on-line criticality surveillance system (IV)

    International Nuclear Information System (INIS)

    Yamada, Sumasu

    2000-02-01

    Developing an inexpensive on-line criticality surveillance system is required for ensuring the safety of nuclear fuel reprocessing plants. Based on the series of researches for five years, R and D study on On-line Criticality Surveillance system has been carried out since 1996. The concept of this Criticality Surveillance System is based on the Auto-Regressive Moving Average (ARMA) model identification algorithms to the time series of signal fluctuation of a neutron detector. We have proposed several new ideas of modification to the original design of the Criticality Surveillance System, and also reported some results of numerical analysis over the DCA experiments. In those days, DOS/V personal computers with Microsoft Windows have came into wide use instead of those based on the MS-DOS, which have been popular in Japan. NEC, a major maker of MS-DOS computers, stopped the production of MS-DOS computers and changed their management policy toward production of DOS/V personal computers. Our researches have been developed using MS-DOS computers. For the effective use of these important results, it became an urgent theme to transplant all programs developed on MS-DOS computers into computers with the OS, which is not easily affected by commercialism. Since the design concept should be based on high reliability, electromagnetic disturbance-free and high expandability, and also computers have achieved remarkably high performance as well as low price in these days, these computers should be used not only as a simple signal processing unit but also a totally integrated signal analyzing system along with conventional signal analyzing software in stead of IC chips with analyzing soft wares. This configuration enables us to easily introduce newly developed techniques and to provide supplement information. Then, this approach can enhance the reliability of the Criticality Surveillance System without addition of any special devices, and also provide the flexibility of the system

  14. In vitro radiosensitivity of six human cell lines. A comparative study with different statistical models

    International Nuclear Information System (INIS)

    Fertil, B.; Deschavanne, P.J.; Lachet, B.; Malaise, E.P.

    1980-01-01

    The intrinsic radiosensitivity of human cell lines (five tumor and one nontransformed fibroblastic) was studied in vitro. The survival curves were fitted by the single-hit multitarget, the two-hit multitarget, the single-hit multitarget with initial slope, and the quadratic models. The accuracy of the experimental results permitted evaluation of the various fittings. Both a statistical test (comparison of variances left unexplained by the four models) and a biological consideration (check for independence of the fitted parameters vis-a-vis the portion of the survival curve in question) were carried out. The quadratic model came out best with each of them. It described the low-dose effects satisfactorily, revealing a single-hit lethal component. This finding and the fact that the six survival curves displayed a continuous curvature ruled out the adoption of the target models as well as the widely used linear regression. As calculated by the quadratic model, the parameters of the six cell lines lead to the following conclusions: (a) the intrinsic radiosensitivity varies greatly among the different cell lines; (b) the interpretation of the fibroblast survival curve is not basically different from that of the tumor cell lines; and (c) the radiosensitivity of these human cell lines is comparable to that of other mammalian cell lines

  15. Dynamic Model for the Z Accelerator Vacuum Section Based on Transmission Line Code%Dynamic Model for the Z Accelerator Vacuum Section Based on Transmission Line Code

    Institute of Scientific and Technical Information of China (English)

    呼义翔; 雷天时; 吴撼宇; 郭宁; 韩娟娟; 邱爱慈; 王亮平; 黄涛; 丛培天; 张信军; 李岩; 曾正中; 孙铁平

    2011-01-01

    The transmission-line-circuit model of the Z accelerator, developed originally by W. A. STYGAR, P. A. CORCORAN, et al., is revised. The revised model uses different calculations for the electron loss and flow impedance in the magnetically insulated transmission line system of the Z accelerator before and after magnetic insulation is established. By including electron pressure and zero electric field at the cathode, a closed set of equations is obtained at each time step, and dynamic shunt resistance (used to represent any electron loss to the anode) and flow impedance are solved, which have been incorporated into the transmission line code for simulations of the vacuum section in the Z accelerator. Finally, the results are discussed in comparison with earlier findings to show the effectiveness and limitations of the model.

  16. Muon Beam Studies in the H4 beam line and the Gamma Irradiation Facility (GIF++)

    CERN Document Server

    Margraf, Rachel; CERN. Geneva. EN Department

    2017-01-01

    In this report, I summarize my work of detailed study and optimization of the muon beam configuration of H4 beam line in SPS North Area. Using Monte-Carlo simulations, I studied the properties and behavior of the muon beam in combination with the field of the large, spectrometer “ GOLIATH” magnet at -1.5, -1.0, 0, 1.0 and 1.5 Tesla, which is shown to affect the central x position of the muon beam that is delivered to the Gamma Irradiation Facility (GIF++). I also studied the muon beam for different configurations of the two XTDV beam dumps upstream of GIF++ in the H4 beam line. I will also discuss my role in mapping the magnetic field of the GOLIATH magnet in the H4 beam line.

  17. Comparison of RAPD, RFLP, AFLP and SSR markers for diversity studies in tropical maize inbred lines

    Directory of Open Access Journals (Sweden)

    Antonio A. F. Garcia

    2004-01-01

    Full Text Available In order to compare their relative efficiencies as markers and to find the most suitable marker for maize diversity studies we evaluated 18 inbred tropical maize lines using a number of different loci as markers. The loci used were: 774 amplified fragment length polymorphisms (AFLPs; 262 random amplified polymorphic DNAs (RAPDs; 185 restriction fragment length polymorphisms (RFLPs; and 68 simple sequence repeats (SSR. For estimating genetic distance the AFLP and RFLP markers gave the most correlated results, with a correlation coefficient of r = 0.87. Bootstrap analysis were used to evaluate the number of loci for the markers and the coefficients of variation (CV revealed a skewed distribution. The dominant markers (AFLP and RAPD had small CV values indicating a skewed distribution while the codominant markers gave high CV values. The use of maximum values of genetic distance CVs within each sample size was efficient in determining the number of loci needed to obtain a maximum CV of 10%. The number of RFLP and AFLP loci used was enough to give CV values of below 5%, while the SSRs and RAPD loci gave higher CV values. Except for the RAPD markers, all the markers correlated genetic distance with single cross performance and heterosis which showed that they could be useful in predicting single cross performance and heterosis in intrapopulation crosses for broad-based populations. Our results indicate that AFLP seemed to be the best-suited molecular assay for fingerprinting and assessing genetic relationships among tropical maize inbred lines with high accuracy.

  18. Role stress among first-line nurse managers and registered nurses - a comparative study.

    Science.gov (United States)

    Johansson, Gunilla; Sandahl, Christer; Hasson, Dan

    2013-04-01

    Studies show that first-line nurse managers (F-LNMs) experience high psychological job demands and inadequate managerial guidance. The purpose of this study was to investigate whether F-LNMs have higher stress levels and show more signs of stress-related ill health than registered nurses (RNs). The aim of this study was to examine possible differences in self-rated health between F-LNMs and RNs on various psychosocial factors (e.g. job demand, job control and managerial support). Data were collected at a university hospital in Sweden. Sixty-four F-LNMs and 908 RNs filled in a web-based questionnaire. Both F-LNMs and RNs reported having good health. Approximately 10-15% of the F-LNMs and RNs showed signs of being at risk for stress-related ill health. Statistically significant differences (Mann-Whitney U-test) were found in the distribution between the F-LNMs and the RNs on three indices of job control, job demand and managerial support. Our findings suggest that F-LNMs were able to cope with high-demand job situations because of relatively high control over work. The implication for nursing management shows the needs for a work environment for both F-LNMs and RNs that includes high job control and good managerial support. © 2011 Blackwell Publishing Ltd.

  19. A Bayesian-Based System to Assess Wave-Driven Flooding Hazards on Coral Reef-Lined Coasts

    Science.gov (United States)

    Pearson, S. G.; Storlazzi, C. D.; van Dongeren, A. R.; Tissier, M. F. S.; Reniers, A. J. H. M.

    2017-12-01

    Many low-elevation, coral reef-lined, tropical coasts are vulnerable to the effects of climate change, sea level rise, and wave-induced flooding. The considerable morphological diversity of these coasts and the variability of the hydrodynamic forcing that they are exposed to make predicting wave-induced flooding a challenge. A process-based wave-resolving hydrodynamic model (XBeach Non-Hydrostatic, "XBNH") was used to create a large synthetic database for use in a "Bayesian Estimator for Wave Attack in Reef Environments" (BEWARE), relating incident hydrodynamics and coral reef geomorphology to coastal flooding hazards on reef-lined coasts. Building on previous work, BEWARE improves system understanding of reef hydrodynamics by examining the intrinsic reef and extrinsic forcing factors controlling runup and flooding on reef-lined coasts. The Bayesian estimator has high predictive skill for the XBNH model outputs that are flooding indicators, and was validated for a number of available field cases. It was found that, in order to accurately predict flooding hazards, water depth over the reef flat, incident wave conditions, and reef flat width are the most essential factors, whereas other factors such as beach slope and bed friction due to the presence or absence of corals are less important. BEWARE is a potentially powerful tool for use in early warning systems or risk assessment studies, and can be used to make projections about how wave-induced flooding on coral reef-lined coasts may change due to climate change.Plain Language SummaryLow-lying tropical coasts fronted by coral reefs are threatened by the effects of climate change, sea level rise, and flooding caused by waves. However, the reefs on these coasts differ widely in their shape, size, and physical characteristics; the wave and water level conditions affecting these coastlines also vary in space and time. These factors make it difficult to predict flooding caused by waves along coral reef-lined coasts. We

  20. The cloud radiative feedback of a midlatitude squall line system and implication for climate study

    International Nuclear Information System (INIS)

    Chin, H.N.S.

    1992-01-01

    The main objectives of this study are (1) to study the impact of longwave and shortwave radiation on the thermodynamic and kinematic structure of a midlatitude squall line; and (2) to explore the influence of specifically including the ice phase in the cloud-radiation feedback mechanism for climate models

  1. On-line event reconstruction using a parallel in-memory data base

    OpenAIRE

    Argante, E; Van der Stok, P D V; Willers, Ian Malcolm

    1995-01-01

    PORS is a system designed for on-line event reconstruction in high energy physics (HEP) experiments. It uses the CPREAD reconstruction program. Central to the system is a parallel in-memory database which is used as communication medium between parallel workers. A farming control structure is implemented with PORS in a natural way. The database provides structured storage of data with a short life time. PORS serves as a case study for the construction of a methodology on how to apply parallel...

  2. Establishing a store baseline during interim storage of waste packages and a review of potential technologies for base-lining

    Energy Technology Data Exchange (ETDEWEB)

    McTeer, Jennifer; Morris, Jenny; Wickham, Stephen [Galson Sciences Ltd. Oakham, Rutland (United Kingdom); Bolton, Gary [National Nuclear Laboratory Risley, Warrington (United Kingdom); McKinney, James; Morris, Darrell [Nuclear Decommissioning Authority Moor Row, Cumbria (United Kingdom); Angus, Mike [National Nuclear Laboratory Risley, Warrington (United Kingdom); Cann, Gavin; Binks, Tracey [National Nuclear Laboratory Sellafield (United Kingdom)

    2013-07-01

    Interim storage is an essential component of the waste management lifecycle, providing a safe, secure environment for waste packages awaiting final disposal. In order to be able to monitor and detect change or degradation of the waste packages, storage building or equipment, it is necessary to know the original condition of these components (the 'waste storage system'). This paper presents an approach to establishing the baseline for a waste-storage system, and provides guidance on the selection and implementation of potential base-lining technologies. The approach is made up of two sections; assessment of base-lining needs and definition of base-lining approach. During the assessment of base-lining needs a review of available monitoring data and store/package records should be undertaken (if the store is operational). Evolutionary processes (affecting safety functions), and their corresponding indicators, that can be measured to provide a baseline for the waste-storage system should then be identified in order for the most suitable indicators to be selected for base-lining. In defining the approach, identification of opportunities to collect data and constraints is undertaken before selecting the techniques for base-lining and developing a base-lining plan. Base-lining data may be used to establish that the state of the packages is consistent with the waste acceptance criteria for the storage facility and to support the interpretation of monitoring and inspection data collected during store operations. Opportunities and constraints are identified for different store and package types. Technologies that could potentially be used to measure baseline indicators are also reviewed. (authors)

  3. Experimental studies on coherent synchrotron radiation at an emittance exchange beam line

    Directory of Open Access Journals (Sweden)

    J. C. T. Thangaraj

    2012-11-01

    Full Text Available One of the goals of the Fermilab A0 photoinjector is to investigate experimentally the transverse to longitudinal emittance exchange (EEX principle. Coherent synchrotron radiation in the emittance exchange line could limit the performance of the emittance exchanger at short bunch lengths. In this paper, we present experimental and simulation studies of the coherent synchrotron radiation (CSR in the emittance exchange line at the A0 photoinjector. We report on time-resolved CSR studies using a skew-quadrupole technique. We also demonstrate the advantages of running the EEX with an energy-chirped beam.

  4. Experimental studies on coherent synchrotron radiation at an emittance exchange beam line

    Science.gov (United States)

    Thangaraj, J. C. T.; Thurman-Keup, R.; Ruan, J.; Johnson, A. S.; Lumpkin, A. H.; Santucci, J.

    2012-11-01

    One of the goals of the Fermilab A0 photoinjector is to investigate experimentally the transverse to longitudinal emittance exchange (EEX) principle. Coherent synchrotron radiation in the emittance exchange line could limit the performance of the emittance exchanger at short bunch lengths. In this paper, we present experimental and simulation studies of the coherent synchrotron radiation (CSR) in the emittance exchange line at the A0 photoinjector. We report on time-resolved CSR studies using a skew-quadrupole technique. We also demonstrate the advantages of running the EEX with an energy-chirped beam.

  5. A Bilevel Programming Model to Optimize Train Operation Based on Satisfaction for an Intercity Rail Line

    Directory of Open Access Journals (Sweden)

    Zhipeng Huang

    2014-01-01

    Full Text Available The passenger travel demands for intercity rail lines fluctuate obviously during different time periods, which makes the rail departments unable to establish an even train operation scheme. This paper considers an optimization problem for train operations which respond to passenger travel demands of different periods in intercity rail lines. A satisfactory function of passenger travelling is proposed by means of analyzing the passengers’ travel choice behavior and correlative influencing factors. On this basis, the paper formulates a bilevel programming model which maximizes interests of railway enterprises and travelling satisfaction of each passenger. The trains operation in different periods can be optimized through upper layer planning of the model, while considering the passenger flow distribution problem based on the Wardrop user equilibrium principle in the lower layer planning. Then, a genetic algorithm is designed according to model features for solving the upper laying. The Frank-Wolfe algorithm is used for solving the lower layer planning. Finally, a numerical example is provided to demonstrate the application of the method proposed in this paper.

  6. Design of Underwater Robot Lines Based on a Hybrid Automatic Optimization Strategy

    Institute of Scientific and Technical Information of China (English)

    Wenjing Lyu; Weilin Luo

    2014-01-01

    In this paper, a hybrid automatic optimization strategy is proposed for the design of underwater robot lines. Isight is introduced as an integration platform. The construction of this platform is based on the user programming and several commercial software including UG6.0, GAMBIT2.4.6 and FLUENT12.0. An intelligent parameter optimization method, the particle swarm optimization, is incorporated into the platform. To verify the strategy proposed, a simulation is conducted on the underwater robot model 5470, which originates from the DTRC SUBOFF project. With the automatic optimization platform, the minimal resistance is taken as the optimization goal;the wet surface area as the constraint condition; the length of the fore-body, maximum body radius and after-body’s minimum radius as the design variables. With the CFD calculation, the RANS equations and the standard turbulence model are used for direct numerical simulation. By analyses of the simulation results, it is concluded that the platform is of high efficiency and feasibility. Through the platform, a variety of schemes for the design of the lines are generated and the optimal solution is achieved. The combination of the intelligent optimization algorithm and the numerical simulation ensures a global optimal solution and improves the efficiency of the searching solutions.

  7. Non-line-of-sight ultraviolet communication based on DHT ACO-OFDM

    Science.gov (United States)

    Gao, Qian; Chen, Gang

    2012-10-01

    Free space optical (FSO) communication has attracted tremendous research interest in the recent year. Most existing works focus only on the line-of-sight (LOS) transmission by infrared (IR) or visible light lasers/LEDs, while this article suggested a framework of non-line-of-sight (NLOS) FSO, motivated by our recent experimental results on the successful transmission of NLOS ultraviolet (UV) beams for up to kilometers, which is comparable to the typical distance a LOS FSO transmission. The NLOS provides an alternate path when the LOS path is shadowed or is highly attenuated. In order to mitigate the multipath dispersion of the NLOS FSO, a baseband orthogonal frequency division multiplexing (OFDM) modulation scheme was proposed, based on Discrete Hartley Transform (DHT) and asymmetric clipping to guarantee the positive-realness of the transmitted optical intensity. The proposed system could reduce the hardware complexity of transmitter and receiver. Minimum mean square error (MMSE) precoder was applied before the DHT to remove the crosstalk between subcarriers, i.e. the frequency domain orthogonality of OFDM was preserved. Performance of the BPSK modulated communication system was given under lognormal atmospheric turbulence for demonstration of the feasibility of the proposed method.

  8. Ultrahigh-rate supercapacitors based on eletrochemically reduced graphene oxide for ac line-filtering

    Science.gov (United States)

    Sheng, Kaixuan; Sun, Yiqing; Li, Chun; Yuan, Wenjing; Shi, Gaoquan

    2012-02-01

    The recent boom in multifunction portable electronic equipments requires the development of compact and miniaturized electronic circuits with high efficiencies, low costs and long lasting time. For the operation of most line-powered electronics, alternating current (ac) line-filters are used to attenuate the leftover ac ripples on direct current (dc) voltage busses. Today, aluminum electrolytic capacitors (AECs) are widely applied for this purpose. However, they are usually the largest components in electronic circuits. Replacing AECs by more compact capacitors will have an immense impact on future electronic devices. Here, we report a double-layer capacitor based on three-dimensional (3D) interpenetrating graphene electrodes fabricated by electrochemical reduction of graphene oxide (ErGO-DLC). At 120-hertz, the ErGO-DLC exhibited a phase angle of -84 degrees, a specific capacitance of 283 microfaradays per centimeter square and a resistor-capacitor (RC) time constant of 1.35 milliseconds, making it capable of replacing AECs for the application of 120-hertz filtering.

  9. Support vector machine based fault classification and location of a long transmission line

    Directory of Open Access Journals (Sweden)

    Papia Ray

    2016-09-01

    Full Text Available This paper investigates support vector machine based fault type and distance estimation scheme in a long transmission line. The planned technique uses post fault single cycle current waveform and pre-processing of the samples is done by wavelet packet transform. Energy and entropy are obtained from the decomposed coefficients and feature matrix is prepared. Then the redundant features from the matrix are taken out by the forward feature selection method and normalized. Test and train data are developed by taking into consideration variables of a simulation situation like fault type, resistance path, inception angle, and distance. In this paper 10 different types of short circuit fault are analyzed. The test data are examined by support vector machine whose parameters are optimized by particle swarm optimization method. The anticipated method is checked on a 400 kV, 300 km long transmission line with voltage source at both the ends. Two cases were examined with the proposed method. The first one is fault very near to both the source end (front and rear and the second one is support vector machine with and without optimized parameter. Simulation result indicates that the anticipated method for fault classification gives high accuracy (99.21% and least fault distance estimation error (0.29%.

  10. Extracting valley-ridge lines from point-cloud-based 3D fingerprint models.

    Science.gov (United States)

    Pang, Xufang; Song, Zhan; Xie, Wuyuan

    2013-01-01

    3D fingerprinting is an emerging technology with the distinct advantage of touchless operation. More important, 3D fingerprint models contain more biometric information than traditional 2D fingerprint images. However, current approaches to fingerprint feature detection usually must transform the 3D models to a 2D space through unwrapping or other methods, which might introduce distortions. A new approach directly extracts valley-ridge features from point-cloud-based 3D fingerprint models. It first applies the moving least-squares method to fit a local paraboloid surface and represent the local point cloud area. It then computes the local surface's curvatures and curvature tensors to facilitate detection of the potential valley and ridge points. The approach projects those points to the most likely valley-ridge lines, using statistical means such as covariance analysis and cross correlation. To finally extract the valley-ridge lines, it grows the polylines that approximate the projected feature points and removes the perturbations between the sampled points. Experiments with different 3D fingerprint models demonstrate this approach's feasibility and performance.

  11. In-Line Sorting of Harumanis Mango Based on External Quality Using Visible Imaging

    Directory of Open Access Journals (Sweden)

    Mohd Firdaus Ibrahim

    2016-10-01

    Full Text Available The conventional method of grading Harumanis mango is time-consuming, costly and affected by human bias. In this research, an in-line system was developed to classify Harumanis mango using computer vision. The system was able to identify the irregularity of mango shape and its estimated mass. A group of images of mangoes of different size and shape was used as database set. Some important features such as length, height, centroid and parameter were extracted from each image. Fourier descriptor and size-shape parameters were used to describe the mango shape while the disk method was used to estimate the mass of the mango. Four features have been selected by stepwise discriminant analysis which was effective in sorting regular and misshapen mango. The volume from water displacement method was compared with the volume estimated by image processing using paired t-test and Bland-Altman method. The result between both measurements was not significantly different (P > 0.05. The average correct classification for shape classification was 98% for a training set composed of 180 mangoes. The data was validated with another testing set consist of 140 mangoes which have the success rate of 92%. The same set was used for evaluating the performance of mass estimation. The average success rate of the classification for grading based on its mass was 94%. The results indicate that the in-line sorting system using machine vision has a great potential in automatic fruit sorting according to its shape and mass.

  12. In-Line Sorting of Harumanis Mango Based on External Quality Using Visible Imaging.

    Science.gov (United States)

    Ibrahim, Mohd Firdaus; Ahmad Sa'ad, Fathinul Syahir; Zakaria, Ammar; Md Shakaff, Ali Yeon

    2016-10-27

    The conventional method of grading Harumanis mango is time-consuming, costly and affected by human bias. In this research, an in-line system was developed to classify Harumanis mango using computer vision. The system was able to identify the irregularity of mango shape and its estimated mass. A group of images of mangoes of different size and shape was used as database set. Some important features such as length, height, centroid and parameter were extracted from each image. Fourier descriptor and size-shape parameters were used to describe the mango shape while the disk method was used to estimate the mass of the mango. Four features have been selected by stepwise discriminant analysis which was effective in sorting regular and misshapen mango. The volume from water displacement method was compared with the volume estimated by image processing using paired t -test and Bland-Altman method. The result between both measurements was not significantly different (P > 0.05). The average correct classification for shape classification was 98% for a training set composed of 180 mangoes. The data was validated with another testing set consist of 140 mangoes which have the success rate of 92%. The same set was used for evaluating the performance of mass estimation. The average success rate of the classification for grading based on its mass was 94%. The results indicate that the in-line sorting system using machine vision has a great potential in automatic fruit sorting according to its shape and mass.

  13. In-Line Sorting of Harumanis Mango Based on External Quality Using Visible Imaging

    Science.gov (United States)

    Ibrahim, Mohd Firdaus; Ahmad Sa’ad, Fathinul Syahir; Zakaria, Ammar; Md Shakaff, Ali Yeon

    2016-01-01

    The conventional method of grading Harumanis mango is time-consuming, costly and affected by human bias. In this research, an in-line system was developed to classify Harumanis mango using computer vision. The system was able to identify the irregularity of mango shape and its estimated mass. A group of images of mangoes of different size and shape was used as database set. Some important features such as length, height, centroid and parameter were extracted from each image. Fourier descriptor and size-shape parameters were used to describe the mango shape while the disk method was used to estimate the mass of the mango. Four features have been selected by stepwise discriminant analysis which was effective in sorting regular and misshapen mango. The volume from water displacement method was compared with the volume estimated by image processing using paired t-test and Bland-Altman method. The result between both measurements was not significantly different (P > 0.05). The average correct classification for shape classification was 98% for a training set composed of 180 mangoes. The data was validated with another testing set consist of 140 mangoes which have the success rate of 92%. The same set was used for evaluating the performance of mass estimation. The average success rate of the classification for grading based on its mass was 94%. The results indicate that the in-line sorting system using machine vision has a great potential in automatic fruit sorting according to its shape and mass. PMID:27801799

  14. A web based on-line radiation early warning system for emergency preparedness and response centre

    International Nuclear Information System (INIS)

    Bhujbal, Vaibhav; Saindane, Shashank S.; Narasaiah, M.V.R.; Murali, S.

    2018-01-01

    The topography of the Bhabha Atomic Research Centre, Trombay site, where all major components of nuclear fuel cycle activities are located is very complex in nature. The assessment of the radiological impact, if any, due to atmospheric releases from these facilities within BARC site is being carried out by using a Local Area Network (LAN) based Radiation Early Warning System and meteorological parameters. The upgraded system is aimed at providing data during normal operation of the various facilities at site and for providing early warning to decision makers in case of any onset of an emergency. It is carried out by acquiring both on-line and off-line data on releases from the plants, the environmental radiation dose rate at selected locations and other related parameters. The monitors placed at these selected locations including strategic point around the BARC site can also help in detecting any attempt of unauthorized trafficking of the radioactive sources. This paper explains different aspects of the system operating at BARC

  15. Bundle Block Adjustment of Airborne Three-Line Array Imagery Based on Rotation Angles

    Directory of Open Access Journals (Sweden)

    Yongjun Zhang

    2014-05-01

    Full Text Available In the midst of the rapid developments in electronic instruments and remote sensing technologies, airborne three-line array sensors and their applications are being widely promoted and plentiful research related to data processing and high precision geo-referencing technologies is under way. The exterior orientation parameters (EOPs, which are measured by the integrated positioning and orientation system (POS of airborne three-line sensors, however, have inevitable systematic errors, so the level of precision of direct geo-referencing is not sufficiently accurate for surveying and mapping applications. Consequently, a few ground control points are necessary to refine the exterior orientation parameters, and this paper will discuss bundle block adjustment models based on the systematic error compensation and the orientation image, considering the principle of an image sensor and the characteristics of the integrated POS. Unlike the models available in the literature, which mainly use a quaternion to represent the rotation matrix of exterior orientation, three rotation angles are directly used in order to effectively model and eliminate the systematic errors of the POS observations. Very good experimental results have been achieved with several real datasets that verify the correctness and effectiveness of the proposed adjustment models.

  16. Data base management study

    Science.gov (United States)

    1976-01-01

    Data base management techniques and applicable equipment are described. Recommendations which will assist potential NASA data users in selecting and using appropriate data base management tools and techniques are presented. Classes of currently available data processing equipment ranging from basic terminals to large minicomputer systems were surveyed as they apply to the needs of potential SEASAT data users. Cost and capabilities projections for this equipment through 1985 were presented. A test of a typical data base management system was described, as well as the results of this test and recommendations to assist potential users in determining when such a system is appropriate for their needs. The representative system tested was UNIVAC's DMS 1100.

  17. 375-nm ultraviolet-laser based non-line-of-sight underwater optical communication

    KAUST Repository

    Sun, Xiaobin; Cai, Wenqi; Alkhazragi, Omar; Ooi, Ee-Ning; He, Hongsen; Chaaban, Anas; Shen, Chao; Oubei, Hassan M.; Khan, Mohammed Zahed Mustafa; Ng, Tien Khee; Alouini, Mohamed-Slim; Ooi, Boon S.

    2018-01-01

    For circumventing the alignment requirement of line-of-sight (LOS) underwater wireless optical communication (UWOC), we demonstrated a non-line-of-sight (NLOS) UWOC link adequately enhanced using ultraviolet (UV) 375-nm laser. Path loss was chosen

  18. Experimental tumor growth of canine osteosarcoma cell line on chick embryo chorioallantoic membrane (in vivo studies).

    Science.gov (United States)

    Walewska, Magdalena; Dolka, Izabella; Małek, Anna; Wojtalewicz, Anna; Wojtkowska, Agata; Żbikowski, Artur; Lechowski, Roman; Zabielska-Koczywąs, Katarzyna

    2017-05-12

    The chick embryo chorioallantoic membrane (CAM) model is extensively used in human medicine in preclinical oncological studies. The CAM model has several advantages: low cost, simple experimental approach, time saving and following "3R principles". Research has shown that the human osteosarcoma cell lines U2OS, MMNG-HOS, and SAOS can form tumors on the CAM. In veterinary medicine, this has been described only for feline fibrosarcomas, feline mammary carcinomas and canine osteosarcomas. However, in case of canine osteosarcomas, it has been shown that only non-adherent osteosarcoma stem cells isolated from KTOSA5 and CSKOS cell lines have the ability to form microtumors on the CAM after an incubation period of 5 days, in contrast to adherent KTOSA5 and CSKOS cells. In the presented study, we have proven that the commercial adherent canine osteosarcoma cell line (D-17) can form vascularized tumors on the CAM after the incubation period of 10 days.

  19. An optimization based method for line planning to minimize travel time

    DEFF Research Database (Denmark)

    Bull, Simon Henry; Lusby, Richard Martin; Larsen, Jesper

    2015-01-01

    The line planning problem is to select a number of lines from a potential pool which provides sufficient passenger capacity and meets operational requirements, with some objective measure of solution line quality. We model the problem of minimizing the average passenger system time, including...

  20. Microprocessor-based, on-line decision aid for resolving conflicting nuclear reactor instrumentation

    International Nuclear Information System (INIS)

    Alesso, H.P.

    1981-01-01

    We describe one design for a microprocessor-based, on-line decision aid for identifying and resolving false, conflicting, or misleading instrument indications resulting from certain systems interactions for a pressurized water reactor. The system processes sensor signals from groups of instruments that track together under nominal transient and certain accident conditions, and alarms when they do not track together. We examine multiple-casualty systems interaction and formulate a trial grouping of variables that track together under specified conditions. A two-of-three type redundancy check of key variables provides alarm and indication of conflicting information when one signal suddenly tracks in opposition due to multiple casualty, instrument failure, and/or locally abnormal conditions. Since a vote count of two of three variables in conflict as inconclusive evidence, the system is not designed to provide tripping or corrective action, but improves the operator/instrument interface by providing additional and partially digested information

  1. Semifragile Speech Watermarking Based on Least Significant Bit Replacement of Line Spectral Frequencies

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Nematollahi

    2017-01-01

    Full Text Available There are various techniques for speech watermarking based on modifying the linear prediction coefficients (LPCs; however, the estimated and modified LPCs vary from each other even without attacks. Because line spectral frequency (LSF has less sensitivity to watermarking than LPC, watermark bits are embedded into the maximum number of LSFs by applying the least significant bit replacement (LSBR method. To reduce the differences between estimated and modified LPCs, a checking loop is added to minimize the watermark extraction error. Experimental results show that the proposed semifragile speech watermarking method can provide high imperceptibility and that any manipulation of the watermark signal destroys the watermark bits since manipulation changes it to a random stream of bits.

  2. Expert System Development on On-line Measurement of Sewage Treatment Based Process

    Directory of Open Access Journals (Sweden)

    Jianjun QIN

    2014-02-01

    Full Text Available This article puts forward a solution in which an instrument on-line automatic measurement and expert system process are optimized according to the complexity and great process dynamics of sewage treatment process. Firstly modeling has been set up with configuration sewage treatment process in which the process has been integrated into the computer software environment. Secondly certain number of water quality automatic monitoring instruments and sensor probes are set in the reaction tanks according to the needs of process changes and management. The data information acquired can be displayed and recorded at the real time. A human-machine integration expert system featuring computer automation management is developed for the base by one-off method thus to realize the intelligent and unmanned management. The advantages brought about from it can fill up the inexperience of the on-site management personnel and solve the contradiction between the water quality dynamics and difficulty in the process adjustment.

  3. New Method to Identify Field Joint Coating Failures Based on MFL In-Line Inspection Signals

    Directory of Open Access Journals (Sweden)

    Lianshuang Dai

    2018-02-01

    Full Text Available Above ground indirect detections and random excavations that have applied the past years for buried long distance oil and gas pipelines can only identify some damaged coating locations. Hence, large number of field joint coating (FJC failures happen unconsciously until they lead to failures of the pipelines. Based on the analysis of magnetic flux leakage (MFL in-line inspection (ILI signals, combined with the statistical results of 414 excavations from two different pipeline sections, a new method to identify the failed FJC is established. Though it can only identify FJC failures when there are signs of corrosion on pipe body, it is much more efficient and cost-saving. The concluded identification rule still needs more validations and improvements to be more applicable and accuracy.

  4. Singularity Processing Method of Microstrip Line Edge Based on LOD-FDTD

    Directory of Open Access Journals (Sweden)

    Lei Li

    2014-01-01

    Full Text Available In order to improve the performance of the accuracy and efficiency for analyzing the microstrip structure, a singularity processing method is proposed theoretically and experimentally based on the fundamental locally one-dimensional finite difference time domain (LOD-FDTD with second-order temporal accuracy (denoted as FLOD2-FDTD. The proposed method can highly improve the performance of the FLOD2-FDTD even when the conductor is embedded into more than half of the cell by the coordinate transformation. The experimental results showed that the proposed method can achieve higher accuracy when the time step size is less than or equal to 5 times of that the Courant-Friedrich-Levy (CFL condition allowed. In comparison with the previously reported methods, the proposed method for calculating electromagnetic field near microstrip line edge not only improves the efficiency, but also can provide a higher accuracy.

  5. A prototype of on-line digital flow rate meter based on cross-correlation principle

    International Nuclear Information System (INIS)

    Sun Xiaodong; Dai Zhenxi; Xu Jijun

    1997-01-01

    An on-line, digital prototype of flow rate measurement system based on cross-correlation principle is developed. Laboratory measurements using the prototype show that sufficiently large temperature fluctuations exist naturally and that measurements are possible. Temperature fluctuations are detected by two identical thermocouples spaced along the flow direction and are pre-processed by a thermocouple signal amplifier. The pre-processed temperature fluctuations are analyzed by a cross-correlator which measures the transit time of temperature fluctuations between two thermocouples directly. Thus, the so-called correlation velocity can be determined by a chip microprocessor 8031. Experimental results with single-phase under steady conditions also show that the distance between two thermocouples and the Reynolds number of fluid are the most important parameters to the measurement

  6. An Entropy-Based Adaptive Hybrid Particle Swarm Optimization for Disassembly Line Balancing Problems

    Directory of Open Access Journals (Sweden)

    Shanli Xiao

    2017-11-01

    Full Text Available In order to improve the product disassembly efficiency, the disassembly line balancing problem (DLBP is transformed into a problem of searching for the optimum path in the directed and weighted graph by constructing the disassembly hierarchy information graph (DHIG. Then, combining the characteristic of the disassembly sequence, an entropy-based adaptive hybrid particle swarm optimization algorithm (AHPSO is presented. In this algorithm, entropy is introduced to measure the changing tendency of population diversity, and the dimension learning, crossover and mutation operator are used to increase the probability of producing feasible disassembly solutions (FDS. Performance of the proposed methodology is tested on the primary problem instances available in the literature, and the results are compared with other evolutionary algorithms. The results show that the proposed algorithm is efficient to solve the complex DLBP.

  7. The Optimization of Passengers’ Travel Time under Express-Slow Mode Based on Suburban Line

    Directory of Open Access Journals (Sweden)

    Xiaobing Ding

    2016-01-01

    Full Text Available The suburban line connects the suburbs and the city centre; it is of huge advantage to attempt the express-slow mode. The passengers’ average travel time is the key factor to reflect the level of rail transport services, especially under the express-slow mode. So it is important to study the passengers’ average travel time under express-slow, which can get benefit on the optimization of operation scheme. First analyze the main factor that affects passengers’ travel time and then mine the dynamic interactive relationship among the factors. Second, a new passengers’ travel time evolution algorithm is proposed after studying the stop schedule and the proportion of express/slow train, and then membrane computing theory algorithm is introduced to solve the model. Finally, Shanghai Metro Line 22 is set as an example to apply the optimization model to calculate the total passengers’ travel time; the result shows that the total average travel time under the express-slow mode can save 1 minute and 38 seconds; the social influence and value of it are very huge. The proposed calculation model is of great help for the decision of stop schedule and provides theoretical and methodological support to determine the proportion of express/slow trains, improves the service level, and enriches and complements the rail transit operation scheme optimization theory system.

  8. Studies of a full-scale mechanical prototype line for the ANTARES neutrino telescope and tests of a prototype instrument for deep-sea acoustic measurements

    Energy Technology Data Exchange (ETDEWEB)

    Ageron, M. [CPPM-Centre de Physique des Particules de Marseille, CNRS/IN2P3 et Universite de la Mediterranee, 163 Avenue de Luminy, Case 902, 13288 Marseille Cedex 9 (France); Aguilar, J.A. [IFIC-Instituto de Fisica Corpuscular, Edificios Investigacion de Paterna, CSIC-Universitat de Valencia, Apdo. de Correos 22085, 46071 Valencia (Spain); Albert, A. [GRPHE-Groupe de Recherche en Physique des Hautes Energies, Universite de Haute Alsace, 61 Rue Albert Camus, 68093 Mulhouse Cedex (France); Ameli, F. [Dipartimento di Fisica dell' Universita ' La Sapienza' e Sezione INFN, P.le Aldo Moro 2, 00185 Roma (Italy); Anghinolfi, M. [Dipartimento di Fisica dell' Universita e Sezione INFN, Via Dodecaneso 33, 16146 Genova (Italy); Anton, G. [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erwin-Rommel-Str. 1, D-91058 Erlangen (Germany); Anvar, S.; Ardellier-Desages, F. [DSM/DAPNIA-Direction des Sciences de la Matiere, Laboratoire de Recherche sur les lois Fondamentales de l' Univers, CEA Saclay, 91191 Gif-sur-Yvette Cedex (France); Aslanides, E.; Aubert, J.-J. [CPPM-Centre de Physique des Particules de Marseille, CNRS/IN2P3 et Universite de la Mediterranee, 163 Avenue de Luminy, Case 902, 13288 Marseille Cedex 9 (France); Auer, R. [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erwin-Rommel-Str. 1, D-91058 Erlangen (Germany); Barbarito, E. [Dipartimento Interateneo di Fisica e Sezione INFN, Via E. Orabona 4, 70126 Bari (Italy); Basa, S. [LAM-Laboratoire d' Astrophysique de Marseille, CNRS/INSU et Universite de Provence, Traverse du Siphon-Les Trois Lucs, BP 8, 13012 Marseille Cedex 12 (France); Battaglieri, M. [Dipartimento di Fisica dell' Universita e Sezione INFN, Via Dodecaneso 33, 16146 Genova (Italy); Bazzotti, M.; Becherini, Y. [Dipartimento di Fisica dell' Universita e Sezione INFN, Viale Berti Pichat 6/2, 40127 Bologna (Italy)] (and others)

    2007-11-01

    A full-scale mechanical prototype line was deployed to a depth of 2500 m to test the leak tightness of the electronics containers and the pressure-resistant properties of an electromechanical cable under evaluation for use in the ANTARES deep-sea neutrino telescope. During a month-long immersion study, line parameter data were taken using miniature autonomous data loggers and shore-based optical time domain reflectometry. Details of the mechanical prototype line, the electromechanical cable and data acquisition are presented. Data taken during the immersion study revealed deficiencies in the pressure resistance of the electromechanical cable terminations at the entry points to the electronics containers. The improvements to the termination, which have been integrated into subsequent detection lines, are discussed. The line also allowed deep-sea acoustic measurements with a prototype hydrophone system. The technical setup of this system is described, and the first results of the data analysis are presented.

  9. Studies of a full-scale mechanical prototype line for the ANTARES neutrino telescope and tests of a prototype instrument for deep-sea acoustic measurements

    International Nuclear Information System (INIS)

    Ageron, M.; Aguilar, J.A.; Albert, A.; Ameli, F.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardellier-Desages, F.; Aslanides, E.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Basa, S.; Battaglieri, M.; Bazzotti, M.; Becherini, Y.

    2007-01-01

    A full-scale mechanical prototype line was deployed to a depth of 2500 m to test the leak tightness of the electronics containers and the pressure-resistant properties of an electromechanical cable under evaluation for use in the ANTARES deep-sea neutrino telescope. During a month-long immersion study, line parameter data were taken using miniature autonomous data loggers and shore-based optical time domain reflectometry. Details of the mechanical prototype line, the electromechanical cable and data acquisition are presented. Data taken during the immersion study revealed deficiencies in the pressure resistance of the electromechanical cable terminations at the entry points to the electronics containers. The improvements to the termination, which have been integrated into subsequent detection lines, are discussed. The line also allowed deep-sea acoustic measurements with a prototype hydrophone system. The technical setup of this system is described, and the first results of the data analysis are presented

  10. Retinal vascular segmentation using superpixel-based line operator and its application to vascular topology estimation.

    Science.gov (United States)

    Na, Tong; Xie, Jianyang; Zhao, Yitian; Zhao, Yifan; Liu, Yue; Wang, Yongtian; Liu, Jiang

    2018-05-09

    Automatic methods of analyzing of retinal vascular networks, such as retinal blood vessel detection, vascular network topology estimation, and arteries/veins classification are of great assistance to the ophthalmologist in terms of diagnosis and treatment of a wide spectrum of diseases. We propose a new framework for precisely segmenting retinal vasculatures, constructing retinal vascular network topology, and separating the arteries and veins. A nonlocal total variation inspired Retinex model is employed to remove the image intensity inhomogeneities and relatively poor contrast. For better generalizability and segmentation performance, a superpixel-based line operator is proposed as to distinguish between lines and the edges, thus allowing more tolerance in the position of the respective contours. The concept of dominant sets clustering is adopted to estimate retinal vessel topology and classify the vessel network into arteries and veins. The proposed segmentation method yields competitive results on three public data sets (STARE, DRIVE, and IOSTAR), and it has superior performance when compared with unsupervised segmentation methods, with accuracy of 0.954, 0.957, and 0.964, respectively. The topology estimation approach has been applied to five public databases (DRIVE,STARE, INSPIRE, IOSTAR, and VICAVR) and achieved high accuracy of 0.830, 0.910, 0.915, 0.928, and 0.889, respectively. The accuracies of arteries/veins classification based on the estimated vascular topology on three public databases (INSPIRE, DRIVE and VICAVR) are 0.90.9, 0.910, and 0.907, respectively. The experimental results show that the proposed framework has effectively addressed crossover problem, a bottleneck issue in segmentation and vascular topology reconstruction. The vascular topology information significantly improves the accuracy on arteries/veins classification. © 2018 American Association of Physicists in Medicine.

  11. Efficient Banknote Recognition Based on Selection of Discriminative Regions with One-Dimensional Visible-Light Line Sensor

    Directory of Open Access Journals (Sweden)

    Tuyen Danh Pham

    2016-03-01

    Full Text Available Banknote papers are automatically recognized and classified in various machines, such as vending machines, automatic teller machines (ATM, and banknote-counting machines. Previous studies on automatic classification of banknotes have been based on the optical characteristics of banknote papers. On each banknote image, there are regions more distinguishable than others in terms of banknote types, sides, and directions. However, there has been little previous research on banknote recognition that has addressed the selection of distinguishable areas. To overcome this problem, we propose a method for recognizing banknotes by selecting more discriminative regions based on similarity mapping, using images captured by a one-dimensional visible light line sensor. Experimental results with various types of banknote databases show that our proposed method outperforms previous methods.

  12. Efficient Banknote Recognition Based on Selection of Discriminative Regions with One-Dimensional Visible-Light Line Sensor.

    Science.gov (United States)

    Pham, Tuyen Danh; Park, Young Ho; Kwon, Seung Yong; Park, Kang Ryoung; Jeong, Dae Sik; Yoon, Sungsoo

    2016-03-04

    Banknote papers are automatically recognized and classified in various machines, such as vending machines, automatic teller machines (ATM), and banknote-counting machines. Previous studies on automatic classification of banknotes have been based on the optical characteristics of banknote papers. On each banknote image, there are regions more distinguishable than others in terms of banknote types, sides, and directions. However, there has been little previous research on banknote recognition that has addressed the selection of distinguishable areas. To overcome this problem, we propose a method for recognizing banknotes by selecting more discriminative regions based on similarity mapping, using images captured by a one-dimensional visible light line sensor. Experimental results with various types of banknote databases show that our proposed method outperforms previous methods.

  13. Novel plasma source for safe beryllium spectral line studies in the presence of beryllium dust

    Science.gov (United States)

    Stankov, B. D.; Vinić, M.; Gavrilović Božović, M. R.; Ivković, M.

    2018-05-01

    Plasma source for beryllium spectral line studies in the presence of beryllium dust particles was realised. The guideline during construction was to prevent exposure to formed dust, considering the toxicity of beryllium. Plasma source characterization through determination of optimal working conditions is described. The necessary conditions for Be spectral line appearance and optimal conditions for line shape measurements are found. It is proven experimentally that under these conditions dust appears coincidently with the second current maximum. The electron density measured after discharge current maximum is determined from the peak separation of the hydrogen Balmer beta spectral line, and the electron temperature is determined from the ratios of the relative intensities of Be spectral lines emitted from successive ionized stages of atoms. Maximum values of electron density and temperature are measured to be 9.3 × 1022 m-3 and 16 800 K, respectively. Construction details and testing of the BeO discharge tube in comparison with SiO2 and Al2O3 discharge tubes are also presented in this paper.

  14. Development of an on-line radon monitoring apparatus and design of the on-line radon monitoring platform based on CAN bus

    International Nuclear Information System (INIS)

    Guo Huiping; Lu Ning; Shang Aiguo; Zhou Chunlin; Chen Yingfen; Yu Hongwei

    2004-12-01

    For actual demand, an idea of 'on-line monitoring' is put forward as a way of radon monitoring, instead of traditional so called 'off-line monitoring'. In this way, the apparatus has some automatic functions such as continuous monitoring, real-time alarm; thereby, there is no need for operators' intervention in each monitoring process. With technique of hardware and software design in automation's field, the authors have successfully developed the prototype and finished the scale of it in a standard radon-chamber. This apparatus is composed of detector part and secondary-instrument. The detector part is made up of a passive diffusion collecting chamber, high voltage static electricity, semiconductor detector, charge-sensitive preamplifier and forming circuit. The secondary-instrument is actually a micro-controller system, which consists of a single-chip micro-controller cored measure-controlling unit, display unit, printing unit and alarming unit. Taking this apparatus as a cell, a 'on-line Radon Monitoring Platform' based on CAN bus has been put forward, which can realize multi-points environmental radioactivity real-time monitoring radioactivity and data process. (authors)

  15. Study of electric and magnetic fields on transmission lines using a computer simulation program

    International Nuclear Information System (INIS)

    Robelo Mojica, Nelson

    2011-01-01

    A study was conducted to determine and reduce levels of electric and magnetic fields with different configurations used by the Instituto Costarricense de Electricidad in power transmission lines in Costa Rica. The computer simulation program PLS-CADD with EPRI algorithm has been used to obtain field values close to those actual to lines easements that have worked to date. Different configurations have been compared on equal terms and the lowest levels of electric and magnetic fields are determined. The most appropriate configuration of the tower has been obtained and therefore has decreased exposure to electromagnetic fields people, without affecting the energy demand of the population. (author) [es

  16. An image overall complexity evaluation method based on LSD line detection

    Science.gov (United States)

    Li, Jianan; Duan, Jin; Yang, Xu; Xiao, Bo

    2017-04-01

    In the artificial world, whether it is the city's traffic roads or engineering buildings contain a lot of linear features. Therefore, the research on the image complexity of linear information has become an important research direction in digital image processing field. This paper, by detecting the straight line information in the image and using the straight line as the parameter index, establishing the quantitative and accurate mathematics relationship. In this paper, we use LSD line detection algorithm which has good straight-line detection effect to detect the straight line, and divide the detected line by the expert consultation strategy. Then we use the neural network to carry on the weight training and get the weight coefficient of the index. The image complexity is calculated by the complexity calculation model. The experimental results show that the proposed method is effective. The number of straight lines in the image, the degree of dispersion, uniformity and so on will affect the complexity of the image.

  17. Experimental analysis of a TEM plane transmission line for DNA studies at 900 MHz EM fields

    International Nuclear Information System (INIS)

    Belloni, F; Doria, D; Lorusso, A; Nassisi, V; Velardi, L; Alifano, P; Monaco, C; Tala, A; Tredici, M; Raino, A

    2006-01-01

    A suitable plane transmission line was developed and its behaviour analysed at 900 MHz radiofrequency fields to study DNA mutability and the repair of micro-organisms. In this work, utilizing such a device, we investigated the behaviour of DNA mutability and repair of Escherichia coli strains. The transmission line was very simple and versatile in changing its characteristic resistance and field intensity by varying its sizes. In the absence of cell samples inside the transmission line, the relative modulation of the electric and/or magnetic field was ±31% with respect to the mean values, allowing the processing of more samples at different exposure fields in a single run. A slight decrease in spontaneous mutability to rifampicin-resistance of the E. coli JC411 strain was demonstrated in mismatch-repair proficient samples exposed to the radio-frequency fields during their growth on solid medium

  18. Comparative study of aerial transmission lines and underground isolated on gas

    International Nuclear Information System (INIS)

    Quesada Jimenez, Marco Esteban

    2012-01-01

    A comparison was made of aerial power lines and underground isolated on gas. Growing electric demand has given way to debate the lines transmission. Multiple discussions have generated about its application, however, the energy must be supplied and this process leads to the search for more efficient methods. The theory has covered the most important design criteria of the airlines and an introduction to the little known transport lines isolated on gas. The process of manufacturing, installation and operation are studied within the scope of the project. Count information is included in the main aspects of calculation relating to power transmission. Besides, the planning of the optimal route nominal calculations, load flow and power losses are focused as well as magnetic field strengths and finally economic analysis. (author) [es

  19. Study of multivariate analysis of quantitative traits in Iranian pumpkin lines

    Directory of Open Access Journals (Sweden)

    Yadegari Mehrab

    2017-01-01

    Full Text Available In this study, seed yield production and its different components fruit length, fruit diameter, fruit length/fruit diameter ratio (FL/FD, diameter of flesh, diameter of seed core, fruit weight, weight of 1000 seed from 24 lines of pumpkin grown in Iran was examined. Twenty-five characters in all plant lines were measured by Descriptor (UPOV and data were subjected to cluster analysis. Results showed that plants lines were divided in four groups. In all groups, regression comparisons were made for modeling the effect of different characters on seed yield, results also showed that fruit weight and fruit length in all groups had the most direct effect on seed yield. In conclusion, these traits are suggested as the best indirect selection criteria to improve the seed yield genetically in Cucurbita spp. genotypes especially in preliminary generation of breeding and selection programs.

  20. Analog study of the second re-extraction line of the La Hague plant

    International Nuclear Information System (INIS)

    Bory, M.; Francois, N.

    1966-01-01

    This study, realized on an analog computer, aims to determine the behavior of an uranium and plutonium re-extraction line in dynamical state. The system perturbations are temperature and acidity variations of aqueous phase and variations of the TBP of the solvent. The uranium contents variations are described. (A.L.B.)

  1. Nitrogen Dynamic Study on Rice Mutant Lines Using 15N Isotope Techniques

    International Nuclear Information System (INIS)

    Ahmad Nazrul Abd Wahid; Shyful Azizi Abdul Rahman; Abdul Rahim Harun

    2015-01-01

    Malaysian Nuclear Agency in collaboration with UPM and MARDI has produced two types of rice mutant lines of MR219, viz. MR219-4 and MR219-9 developed under rice radiation mutagenenesis programme for adaptability to aerobic conditions. Aerobic cultivating is rice cultivation system on well drained soil and using minimal water input. At Malaysian Nuclear Agency, a nitrogen fertilization study in aerobic condition for the rice mutant lines was carried out in the shade house and field. The study is intended to examine and assess the dynamics of nitrogen by rice mutant lines through the different soil water management and nitrogen levels. Direct 15 N isotopic tracer method was used in this study, whereby the 15 N labeled urea fertilizer was utilized as a tracer for nitrogen nutrient uptake by the test crops. This paper is intended to highlight the progress that has been made in the study of the nitrogen dynamics on MR219-4 and MR219-9 rice mutant lines. (author)

  2. Studies on the potency of oral polio vaccine using RD cell line and ...

    African Journals Online (AJOL)

    Studies on the potency of oral polio vaccine using RD cell line and evaluation of growth using different serum concentration and volume of media. ... The culture flasks containing different volumes of growth medium with 10% serum concentration such as 8, 9, 10, 11 and 12 ml were added to a series of culture flasks. All the ...

  3. Study of abrasive wear process of lining of grinding chamber of vortex-acoustic disperser

    Science.gov (United States)

    Perelygin, D. N.

    2018-03-01

    The theoretical and experimental studies of the process of gas-abrasive wear of the lining of a vortex-acoustic disperser made it possible to establish the conditions and patterns of their occurrence and also to develop proposals for its reduction.

  4. External Reporting Lines of Academic Special Libraries: A Health Sciences Case Study

    Science.gov (United States)

    Buhler, Amy G.; Ferree, Nita; Cataldo, Tara T.; Tennant, Michele R.

    2010-01-01

    Very little literature exists on the nature of external reporting lines and funding structures of academic special libraries. This study focuses on academic health sciences libraries. The authors analyze information gathered from statistics published by the Association of Academic Health Sciences Libraries (AAHSL) from 1977 through 2007; an…

  5. Adaptive Marginal Costs-Based Distributed Economic Control of Microgrid Clusters Considering Line Loss

    Directory of Open Access Journals (Sweden)

    Xiaoqian Zhou

    2017-12-01

    Full Text Available When several microgrids (MG are interconnected into microgrid clusters (MGC, they have great potential to improve their reliability. Traditional droop control tends to make the total operating costs higher as the power is distributed by capacity ratios of distributed energy resources (DERs. This paper proposes an adaptive distributed economic control for islanded microgrids which considers line loss, specifically, an interesting marginal costs-based economic droop control is proposed, and consensus-based adaptive controller is applied, to deal with power limits and capacity constraints for storage. The whole expense can be effectively lowered by achieving identical marginal costs for DERs in MGC. Specially, the capacity constraints only for storages are also included to do further optimization. Moreover, consensus-based distributed secondary controllers are used to rapidly restore system frequency and voltage magnitudes. The above controllers only need to interact with neighbor DERs by a sparse communication network, eliminating the necessity of a central controller and enhancing the stability. A MGC, incorporating three microgrids, is used to verify the effectiveness of the proposed methods.

  6. A new normalization method based on electrical field lines for electrical capacitance tomography

    International Nuclear Information System (INIS)

    Zhang, L F; Wang, H X

    2009-01-01

    Electrical capacitance tomography (ECT) is considered to be one of the most promising process tomography techniques. The image reconstruction for ECT is an inverse problem to find the spatially distributed permittivities in a pipe. Usually, the capacitance measurements obtained from the ECT system are normalized at the high and low permittivity for image reconstruction. The parallel normalization model is commonly used during the normalization process, which assumes the distribution of materials in parallel. Thus, the normalized capacitance is a linear function of measured capacitance. A recently used model is a series normalization model which results in the normalized capacitance as a nonlinear function of measured capacitance. The newest presented model is based on electrical field centre lines (EFCL), and is a mixture of two normalization models. The multi-threshold method of this model is presented in this paper. The sensitivity matrices based on different normalization models were obtained, and image reconstruction was carried out accordingly. Simulation results indicate that reconstructed images with higher quality can be obtained based on the presented model

  7. Detection of vegetation LUE based on chlorophyll fluorescence separation algorithm from Fraunhofer line

    Science.gov (United States)

    Liu, Liangyun; Zhang, Bing

    2009-09-01

    Photosynthetic efficiency is very important, and not yet generally assessable by remote sensing. Much research has proved the possibility of the separation of solar-induced chlorophyll fluorescence (ChlF) from the reflected hyperspectral data. As the 'probe' of plant photosynthesis, it is possible to detect photosynthetic light use efficiency (LUE) by the separated solar-induced ChlF. A diurnal experiment was carried out on winter wheat on Apr. 18, 2008, and the canopy radiance spectra and leaf LUE data were measured synchronously. The solar-induced chlorophyll fluorescence signals at 760nm and 688nm were separated from the reflected radiance spectral based on Fraunhofer lines in two oxygen absorption bands. The result showed that LUE was negatively correlated to the separated chlorophyll signals. The statistical models for LUE based on the solar-induced chlorophyll fluorescence values at 688 nm and 760 nm bands had correlation coefficients (R2) of 0.64 and 0.78, respectively. In addition, photochemical reflectance index (PRI) was also linked to LUE, and a statistical model for LUE based on PRI has a correlation coefficient (R2) of 0.66. The presented method provides a novel solution for monitoring LUE from remote sensing data.

  8. On-line monitoring system of PV array based on internet of things technology

    Science.gov (United States)

    Li, Y. F.; Lin, P. J.; Zhou, H. F.; Chen, Z. C.; Wu, L. J.; Cheng, S. Y.; Su, F. P.

    2017-11-01

    The Internet of Things (IoT) Technology is used to inspect photovoltaic (PV) array which can greatly improve the monitoring, performance and maintenance of the PV array. In order to efficiently realize the remote monitoring of PV operating environment, an on-line monitoring system of PV array based on IoT is designed in this paper. The system includes data acquisition, data gateway and PV monitoring centre (PVMC) website. Firstly, the DSP-TMS320F28335 is applied to collect indicators of PV array using sensors, then the data are transmitted to data gateway through ZigBee network. Secondly, the data gateway receives the data from data acquisition part, obtains geographic information via GPS module, and captures the scenes around PV array via USB camera, then uploads them to PVMC website. Finally, the PVMC website based on Laravel framework receives all data from data gateway and displays them with abundant charts. Moreover, a fault diagnosis approach for PV array based on Extreme Learning Machine (ELM) is applied in PVMC. Once fault occurs, a user alert can be sent via E-mail. The designed system enables users to browse the operating conditions of PV array on PVMC website, including electrical, environmental parameters and video. Experimental results show that the presented monitoring system can efficiently real-time monitor the PV array, and the fault diagnosis approach reaches a high accuracy of 97.5%.

  9. Effect of surface treatments on the bond strength of soft denture lining materials to an acrylic resin denture base.

    Science.gov (United States)

    Gundogdu, Mustafa; Yesil Duymus, Zeynep; Alkurt, Murat

    2014-10-01

    Adhesive failure between acrylic resin and resilient liner material is commonly encountered in clinical practice. The purpose of this study was to evaluate the effect of different surface treatments on the bond strength of 2 different resilient lining materials to an acrylic resin denture base. Ninety-six dumbbell-shaped specimens were fabricated from heat-polymerized acrylic resin, and 3 mm of the material was cut from the thin midsection. The specimens were divided into 6 groups according to their surface treatments: no surface treatment (control group), 36% phosphoric acid etching (acid group), erbium:yttrium-aluminum-garnet (Er:YAG) laser (laser group), airborne-particle abrasion with 50-μm Al2O3 particles (abrasion group), an acid+laser group, and an abrasion+laser group. The specimens in each group were divided into 2 subgroups according to the resilient lining material used: heat-polymerized silicone based resilient liner (Molloplast B) and autopolymerized silicone-based resilient liner (Ufi Gel P). After all of the specimens had been polymerized, they were stored in distilled water at 37°C for 1 week. A tensile bond strength test was then performed. Data were analyzed with a 2-way ANOVA, and the Sidak multiple comparison test was used to identify significant differences (α=.05). The effects of the surface treatments and resilient lining materials on the surface of the denture base resin were examined with scanning electron microscopy. The tensile bond strength was significantly different between Molloplast B and Ufi Gel P (P<.001). The specimens of the acid group had the highest tensile bond strength, whereas those of the abrasion group had the lowest tensile bond strength. The scanning electron microscopy observations showed that the application of surface treatments modified the surface of the denture base resin. Molloplast B exhibited significantly higher bond strength than Ufi Gel P. Altering the surface of the acrylic resin denture base with 36

  10. New chondrosarcoma cell lines and mouse models to study the link between chondrogenesis and chemoresistance.

    Science.gov (United States)

    Monderer, David; Luseau, Alexandrine; Bellec, Amélie; David, Emmanuelle; Ponsolle, Stéphanie; Saiagh, Soraya; Bercegeay, Sylvain; Piloquet, Philippe; Denis, Marc G; Lodé, Laurence; Rédini, Françoise; Biger, Marine; Heymann, Dominique; Heymann, Marie-Françoise; Le Bot, Ronan; Gouin, François; Blanchard, Frédéric

    2013-10-01

    Chondrosarcomas are cartilage-forming, poorly vascularized tumors. They represent the second malignant primary bone tumor of adults after osteosarcoma, but in contrast to osteosarcoma they are resistant to chemotherapy and radiotherapy, surgical excision remaining the only therapeutic option. Few cell lines and animal models are available, and the mechanisms behind their chemoresistance remain largely unknown. Our goal was to establish new cell lines and animal cancer models from human chondrosarcoma biopsies to study their chemoresistance. Between 2007 and 2012, 10 chondrosarcoma biopsies were collected and used for cell culture and transplantation into nude mice. Only one transplanted biopsy and one injected cell line has engrafted successfully leading to conventional central high-grade chondrosarcoma similar to the original biopsies. In culture, two new stable cell lines were obtained, one from a dedifferentiated and one from a grade III conventional central chondrosarcoma biopsy. Their genetic characterization revealed triploid karyotypes, mutations in IDH1, IDH2, and TP53, deletion in CDKN2A and/or MDM2 amplification. These cell lines expressed mesenchymal membrane markers (CD44, 73, 90, 105) and were able to produce a hyaline cartilaginous matrix when cultured in chondrogenic three-dimensional (3D) pellets. Using a high-throughput quantitative RT-PCR approach, we observed that cell lines cultured in monolayer had lost expression of several genes implicated in cartilage development (COL2A1, COMP, ACAN) but restored their expression in 3D cultures. Chondrosarcoma cells in monolayer were sensitive to several conventional chemotherapeutic agents but became resistant to low doses of mafosfamide or doxorubicin when cultured in 3D pellets, in parallel with an altered nucleic accumulation of the drug. Our results indicate that the cartilaginous matrix produced by chondrosarcoma cells may impair diffusion of several drugs and thus contribute to chemoresistance

  11. Establishment of optimized MDCK cell lines for reliable efflux transport studies.

    Science.gov (United States)

    Gartzke, Dominik; Fricker, Gert

    2014-04-01

    Madin-Darby canine kidney (MDCK) cells transfected with human MDR1 gene (MDCK-MDR1) encoding for P-glycoprotein (hPgp, ABCB1) are widely used for transport studies to identify drug candidates as substrates of this efflux protein. Therefore, it is necessary to rely on constant and comparable expression levels of Pgp to avoid false negative or positive results. We generated a cell line with homogenously high and stable expression of hPgp through sorting single clones from a MDCK-MDR1 cell pool using fluorescence-activated cell sorting (FACS). To obtain control cell lines for evaluation of cross-interactions with endogenous canine Pgp (cPgp) wild-type cells were sorted with a low expression pattern of cPgp in comparison with the MDCK-MDR1. Expression of other transporters was also characterized in both cell lines by quantitative real-time PCR and Western blot. Pgp function was investigated applying the Calcein-AM assay as well as bidirectional transport assays using (3) H-Digoxin, (3) H-Vinblastine, and (3) H-Quinidine as substrates. Generated MDCK-MDR1 cell lines showed high expression of hPgp. Control MDCK-WT cells were optimized in showing a comparable expression level of cPgp in comparison with MDCK-MDR1 cell lines. Generated cell lines showed higher and more selective Pgp transport compared with parental cells. Therefore, they provide a significant improvement in the performance of efflux studies yielding more reliable results. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  12. Case Report of First Angiography-Based On-Line FFR Assessment during Coronary Catheterization.

    Science.gov (United States)

    Kornowski, Ran; Vaknin-Assa, Hana

    2017-01-01

    Fractional flow reserve (FFR), an index of the hemodynamic severity of coronary stenoses, is derived from hyperemic pressure measurements and requires a pressure-monitoring guide wire and hyperemic stimulus. Although it has become the standard of reference for decision-making regarding coronary revascularization, the procedure remains underutilized due to its invasive nature. FFR angio is a novel technology that uses the patient's hemodynamic data and routine angiograms to generate a complete three-dimensional coronary tree, with color-coded display of the FFR values at each point along the vessels. After being proven to be as accurate as invasive FFR measurements in an off-line study, this case report presents the first on-line application of the system in the catheterization lab. Here too, a high concordance between FFR angio and invasive FFR was observed. In light of the demonstrated capabilities of the FFR angio system, it should emerge as an important tool for clinical decision-making regarding revascularization in patients with coronary artery disease.

  13. Case Report of First Angiography-Based On-Line FFR Assessment during Coronary Catheterization

    Directory of Open Access Journals (Sweden)

    Ran Kornowski

    2017-01-01

    Full Text Available Fractional flow reserve (FFR, an index of the hemodynamic severity of coronary stenoses, is derived from hyperemic pressure measurements and requires a pressure-monitoring guide wire and hyperemic stimulus. Although it has become the standard of reference for decision-making regarding coronary revascularization, the procedure remains underutilized due to its invasive nature. FFRangio is a novel technology that uses the patient’s hemodynamic data and routine angiograms to generate a complete three-dimensional coronary tree, with color-coded display of the FFR values at each point along the vessels. After being proven to be as accurate as invasive FFR measurements in an off-line study, this case report presents the first on-line application of the system in the catheterization lab. Here too, a high concordance between FFRangio and invasive FFR was observed. In light of the demonstrated capabilities of the FFRangio system, it should emerge as an important tool for clinical decision-making regarding revascularization in patients with coronary artery disease.

  14. Asymmetrical flow field-flow fractionation with on-line detection for drug transfer studies: a feasibility study

    DEFF Research Database (Denmark)

    Hinna, A.; Steiniger, F.; Hupfeld, S.

    2014-01-01

    Knowledge about drug retention within colloidal carriers is of uppermost importance particularly if drug targeting is anticipated. The aim of the present study was to evaluate asymmetrical flow field-flow fractionation (AF4) with on-line UV/VIS drug quantification for its suitability to determine...... both release and transfer of drug from liposomal carriers to a model acceptor phase consisting of large liposomes. The hydrophobic porphyrin 5,10,15,20-tetrakis(4-hydroxyphenyl)21H,23H-porphine (p-THPP), a fluorescent dye with an absorbance maximum in the visible range and structural similarity...... channel geometries. Drug quantification by on-line absorbance measurements was established by comprehensive evaluation of the size-dependent turbidity contribution in on-line UV/VIS detection and by comparison with off-line results obtained for the respective dye-loaded donor formulations (dissolved...

  15. Contribution to the study of an on line inspection system for pulsed Nd:YAG laser welding operations

    International Nuclear Information System (INIS)

    Charton, Stephane

    1999-01-01

    This thesis deals with the study of a on line inspection system for pulsed Nd 3+ :YAG laser welding operations. During a welding operation, laser-material interaction results in the emission of signals (optical, acoustical, electrical, thermal), characteristic of its behavior. On line inspection is based on the hypothesis that the signals evolutions, measured by sensors such as photodiodes, microphones.., may be correlated with the welding defects. Laser weld quality inspection can be done by the machine qualification (before and during welding), and by on line monitoring of the welding operation. The similarity of the signals produced by pulsed lasers (machine or interaction) has led us to develop a specific data acquisition and processing software. Signal processing tools utilization (Fourier and wavelets transforms) in conjunction with classification techniques (stress polytopes), introduces an innovating on line inspection approach. Discriminant parameters determination (signals/defect correlation) becomes thus automatic and non subjective. The developed prototype is not dedicated to the detection of a particular defect because the classification operator is a supervised one and needs a learning phase. lt has been validated on welding defects which are easy to deal with, and then applied to a precise production control at the Nuclear Fabrications and Technology Division of the Valduc Center of the French Atomic Energy Agency. (author) [fr

  16. submitter Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

    CERN Document Server

    Scisciò, M; Migliorati, M; Mostacci, A; Palumbo, L; Papaphilippou, Y; Antici, P

    2016-01-01

    In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequency (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupo...

  17. Study of condensation heat transfer following a main steam line break inside containment

    Energy Technology Data Exchange (ETDEWEB)

    Cho, J.H.; Elia, F.A. Jr.; Lischer, D.J. [Stone & Webster Engineering Corporation, Boston, MA (United States)

    1995-09-01

    An alternative model for calculating condensation heat transfer following a main stream line break (MSLB) accident is proposed. The proposed model predictions and the current regulatory model predictions are compared to the results of the Carolinas Virginia Tube Reactor (CVTR) test. The very conservative results predicted by the current regulatory model result from: (1) low estimate of the condensation heat transfer coefficient by the Uchida correlation and (2) neglecting the convective contribution to the overall heat transfer. Neglecting the convection overestimates the mass of steam being condensed and does not permit the calculation of additional convective heat transfer resulting from superheated conditions. In this study, the Uchida correlation is used, but correction factors for the effects of convection an superheat are derived. The proposed model uses heat and mass transfer analogy methods to estimate to convective fraction of the total heat transfer and bases the steam removal rate on the condensation heat transfer portion only. The results predicted by the proposed model are shown to be conservative and more accurate than those predicted by the current regulatory model when compared with the results of the CVTR test. Results for typical pressurized water reactors indicate that the proposed model provides a basis for lowering the equipment qualification temperature envelope, particularly at later times following the accident.

  18. On a Hopping-Points SVD and Hough Transform-Based Line Detection Algorithm for Robot Localization and Mapping

    Directory of Open Access Journals (Sweden)

    Abhijeet Ravankar

    2016-05-01

    Full Text Available Line detection is an important problem in computer vision, graphics and autonomous robot navigation. Lines detected using a laser range sensor (LRS mounted on a robot can be used as features to build a map of the environment, and later to localize the robot in the map, in a process known as Simultaneous Localization and Mapping (SLAM. We propose an efficient algorithm for line detection from LRS data using a novel hopping-points Singular Value Decomposition (SVD and Hough transform-based algorithm, in which SVD is applied to intermittent LRS points to accelerate the algorithm. A reverse-hop mechanism ensures that the end points of the line segments are accurately extracted. Line segments extracted from the proposed algorithm are used to form a map and, subsequently, LRS data points are matched with the line segments to localize the robot. The proposed algorithm eliminates the drawbacks of point-based matching algorithms like the Iterative Closest Points (ICP algorithm, the performance of which degrades with an increasing number of points. We tested the proposed algorithm for mapping and localization in both simulated and real environments, and found it to detect lines accurately and build maps with good self-localization.

  19. First-principles studies of chromium line-ordered alloys in a molybdenum disulfide monolayer

    Science.gov (United States)

    Andriambelaza, N. F.; Mapasha, R. E.; Chetty, N.

    2017-08-01

    Density functional theory calculations have been performed to study the thermodynamic stability, structural and electronic properties of various chromium (Cr) line-ordered alloy configurations in a molybdenum disulfide (MoS2) hexagonal monolayer for band gap engineering. Only the molybdenum (Mo) sites were substituted at each concentration in this study. For comparison purposes, different Cr line-ordered alloy and random alloy configurations were studied and the most thermodynamically stable ones at each concentration were identified. The configurations formed by the nearest neighbor pair of Cr atoms are energetically most favorable. The line-ordered alloys are constantly lower in formation energy than the random alloys at each concentration. An increase in Cr concentration reduces the lattice constant of the MoS2 system following the Vegard’s law. From density of states analysis, we found that the MoS2 band gap is tunable by both the Cr line-ordered alloys and random alloys with the same magnitudes. The reduction of the band gap is mainly due to the hybridization of the Cr 3d and Mo 4d orbitals at the vicinity of the band edges. The band gap engineering and magnitudes (1.65 eV to 0.86 eV) suggest that the Cr alloys in a MoS2 monolayer are good candidates for nanotechnology devices.

  20. Registration of Aerial Image with Airborne LiDAR Data Based on Plücker Line

    Directory of Open Access Journals (Sweden)

    SHENG Qinghong

    2015-07-01

    Full Text Available Registration of aerial image with airborne LiDAR data is a key to feature extraction. A registration model based on Plücker line is proposed. The relative position and attitude relationship between the conjugate lines in LiDAR and image is determined based on Plücker linear equation, which describes line transformation in space, then coplanarity condition equation is established. Finally, coordinate transformation between image point and corresponding LiDAR point is achieved by the spiral movement of Plücker lines in the image. The registration model of Plücker linear coplanarity condition equation is simple, and jointly describes the rotation and translation to avoid coupling error between them, so the accuracy is approved. This research provides technical support for high-quality earth spatial information acquisition.

  1. Estimation of flashover voltage probability of overhead line insulators under industrial pollution, based on maximum likelihood method

    International Nuclear Information System (INIS)

    Arab, M.N.; Ayaz, M.

    2004-01-01

    The performance of transmission line insulator is greatly affected by dust, fumes from industrial areas and saline deposit near the coast. Such pollutants in the presence of moisture form a coating on the surface of the insulator, which in turn allows the passage of leakage current. This leakage builds up to a point where flashover develops. The flashover is often followed by permanent failure of insulation resulting in prolong outages. With the increase in system voltage owing to the greater demand of electrical energy over the past few decades, the importance of flashover due to pollution has received special attention. The objective of the present work was to study the performance of overhead line insulators in the presence of contaminants such as induced salts. A detailed review of the literature and the mechanisms of insulator flashover due to the pollution are presented. Experimental investigations on the behavior of overhead line insulators under industrial salt contamination are carried out. A special fog chamber was designed in which the contamination testing of insulators was carried out. Flashover behavior under various degrees of contamination of insulators with the most common industrial fume components such as Nitrate and Sulphate compounds was studied. Substituting the normal distribution parameter in the probability distribution function based on maximum likelihood develops a statistical method. The method gives a high accuracy in the estimation of the 50% flashover voltage, which is then used to evaluate the critical flashover index at various contamination levels. The critical flashover index is a valuable parameter in insulation design for numerous applications. (author)

  2. User Assessment of "InsuOnLine," a Game to Fight Clinical Inertia in Diabetes: A Pilot Study.

    Science.gov (United States)

    Diehl, Leandro Arthur; de Souza, Rodrigo Martins; Gordan, Pedro Alejandro; Esteves, Roberto Zonato; Coelho, Izabel Cristina Meister

    2015-10-01

    We performed a pilot study to assess usability and playability of "InsuOnLine," a serious game for education of primary care physicians on insulin therapy for diabetes mellitus. A multidisciplinary team has designed and developed "InsuOnLine," using Andragogy and Problem-Based Learning principles, with game elements to improve players' motivation. The prototype was tested by four medical doctors and two medical students, using the System Usability Scale (SUS) and a questionnaire to assess playability. These results were used to guide corrections, after which the beta version was retested by 14 medical students and 6 residents. Out of a maximum score of 100 on the SUS, the "InsuOnLine" prototype was rated 88, and some areas for improvement were identified (game instructions, controls). After corrections, the beta version was rated 92.5 on the SUS. Users have found the beta version to be fun, engaging, challenging, relevant, and realistic. Users said that the game has increased their knowledge on diabetes and insulin, that it has made them feel more confident for prescribing insulin, and that it would have impact on how they treated patients with diabetes. Most users said they have learned more from the game than they would have from a lecture. Lessons learned were the need of early piloting, preferably by users with very little or very much gaming experience, on their own computers and free patterns of use. "InsuOnLine" was rated by users as easy to play, fun, and useful for learning. Further studies will assess its educational effectiveness. "InsuOnLine" is a promising tool for large-scale continuing medical education on insulin, helping to fight clinical inertia in diabetes.

  3. Treatment of hepatic encephalopathy by on-line hemodiafiltration: a case series study

    Directory of Open Access Journals (Sweden)

    Sugiyama Mitsugi

    2010-05-01

    Full Text Available Abstract Background It is thought that a good survival rate of patients with acute liver failure can be achieved by establishing an artificial liver support system that reliably compensates liver function until the liver regenerates or a patient undergoes transplantation. We introduced a new artificial liver support system, on-line hemodiafiltration, in patients with acute liver failure. Methods This case series study was conducted from May 2001 to October 2008 at the medical intensive care unit of a tertiary care academic medical center. Seventeen consecutive patients who admitted to our hospital presenting with acute liver failure were treated with artificial liver support including daily on-line hemodiafiltration and plasma exchange. Results After 4.9 ± 0.7 (mean ± SD on-line hemodiafiltration sessions, 16 of 17 (94.1% patients completely recovered from hepatic encephalopathy and maintained consciousness for 16.4 ± 3.4 (7-55 days until discontinuation of artificial liver support (a total of 14.4 ± 2.6 [6-47] on-line hemodiafiltration sessions. Significant correlation was observed between the degree of encephalopathy and number of sessions of on-line HDF required for recovery of consciousness. Of the 16 patients who recovered consciousness, 7 fully recovered and returned to society with no cognitive sequelae, 3 died of complications of acute liver failure except brain edema, and the remaining 6 were candidates for liver transplantation; 2 of them received living-related liver transplantation but 4 died without transplantation after discontinuation of therapy. Conclusions On-line hemodiafiltration was effective in patients with acute liver failure, and consciousness was maintained for the duration of artificial liver support, even in those in whom it was considered that hepatic function was completely abolished.

  4. CONSTRAINING JET PRODUCTION SCENARIOS BY STUDIES OF NARROW-LINE RADIO GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Sikora, Marek [Nicolaus Copernicus Astronomical Center, Bartycka 18, 00-716 Warsaw (Poland); Stasinska, Grazyna [LUTH, Observatoire de Paris, CNRS, Universite Paris Diderot, Place Jules Janssen, F-92190 Meudon (France); Koziel-Wierzbowska, Dorota [Astronomical Observatory, Jagiellonian University, ul. Orla 171, 30-244 Krakow (Poland); Madejski, Greg M. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, CA 94305 (United States); Asari, Natalia V., E-mail: sikora@camk.edu.pl [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom)

    2013-03-01

    We study a large sample of narrow-line radio galaxies (NLRGs) with extended radio structures. Using 1.4 GHz radio luminosities L {sub 1.4}, narrow optical emission line luminosities L {sub [OIII]} and L{sub H{sub {alpha}}}, as well as black hole masses M {sub BH} derived from stellar velocity dispersions measured from the optical spectra obtained with the Sloan Digital Sky Survey, we find that (1) NLRGs cover about four decades of the Eddington ratio, {lambda} {identical_to} L {sub bol}/L {sub Edd}{proportional_to}L {sub line}/M {sub BH}; (2) L {sub 1.4}/M {sub BH} strongly correlates with {lambda}; and (3) radio loudness, R{identical_to}L{sub 1.4}/L{sub line}, strongly anti-correlates with {lambda}. A very broad range of the Eddington ratio indicates that the parent population of NLRGs includes both radio-loud quasars (RLQs) and broad-line radio galaxies (BLRGs). The correlations they obey and their high jet production efficiencies favor a jet production model which involves the so-called magnetically choked accretion scenario. In this model, production of the jet is dominated by the Blandford-Znajek mechanism, and the magnetic fields in the vicinity of the central black hole are confined by the ram pressure of the accretion flow. Since large net magnetic flux accumulated in central regions of the accretion flow required by the model can take place only via geometrically thick accretion, we speculate that the massive, 'cold' accretion events associated with luminous emission-line active galactic nucleus can be accompanied by an efficient jet production only if preceded by a hot, very sub-Eddington accretion phase.

  5. SICS. A Sensor-Based In-Line Control System for the Surfaces of Continuously Cast Slabs

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Tzyy-Shuh [OG Technologies, Inc., Ann Arbor, MI (United States)

    2013-09-23

    The Phase II project has been carried out in accordance to the proposed tasks and budget, based on the original and extended schedule. The R&D team designed and implemented the test unit for the full width coverage, installed the unit in a caster. The development work further included enhanced image processing, in-depth defect study and process control models. The function, operation, and maintenance of the SICS was thoroughly studied during the Phase II research. The experience indicates additional hardware and procedures are required to make the SICS a commercially ready product in operation and maintenance aspect. Such developments have been finished and the team is contacting potential customers for the first commercial installation of SICS. Additionally, OGT is exploring the possibility to team up with a US company that specializes in surface cleaning for slabs/blooms/billets such that the in-line surface inspection can be integrated with in-line surface clean up for the maximum benefit to the steel industry.

  6. Inspection Robot Based Mobile Sensing and Power Line Tracking for Smart Grid

    Directory of Open Access Journals (Sweden)

    Bat-erdene Byambasuren

    2016-02-01

    Full Text Available Smart sensing and power line tracking is very important in a smart grid system. Illegal electricity usage can be detected by remote current measurement on overhead power lines using an inspection robot. There is a need for accurate detection methods of illegal electricity usage. Stable and correct power line tracking is a very prominent issue. In order to correctly track and make accurate measurements, the swing path of a power line should be previously fitted and predicted by a mathematical function using an inspection robot. After this, the remote inspection robot can follow the power line and measure the current. This paper presents a new power line tracking method using parabolic and circle fitting algorithms for illegal electricity detection. We demonstrate the effectiveness of the proposed tracking method by simulation and experimental results.

  7. Inspection Robot Based Mobile Sensing and Power Line Tracking for Smart Grid.

    Science.gov (United States)

    Byambasuren, Bat-Erdene; Kim, Donghan; Oyun-Erdene, Mandakh; Bold, Chinguun; Yura, Jargalbaatar

    2016-02-19

    Smart sensing and power line tracking is very important in a smart grid system. Illegal electricity usage can be detected by remote current measurement on overhead power lines using an inspection robot. There is a need for accurate detection methods of illegal electricity usage. Stable and correct power line tracking is a very prominent issue. In order to correctly track and make accurate measurements, the swing path of a power line should be previously fitted and predicted by a mathematical function using an inspection robot. After this, the remote inspection robot can follow the power line and measure the current. This paper presents a new power line tracking method using parabolic and circle fitting algorithms for illegal electricity detection. We demonstrate the effectiveness of the proposed tracking method by simulation and experimental results.

  8. A Line-Based Adaptive-Weight Matching Algorithm Using Loopy Belief Propagation

    Directory of Open Access Journals (Sweden)

    Hui Li

    2015-01-01

    Full Text Available In traditional adaptive-weight stereo matching, the rectangular shaped support region requires excess memory consumption and time. We propose a novel line-based stereo matching algorithm for obtaining a more accurate disparity map with low computation complexity. This algorithm can be divided into two steps: disparity map initialization and disparity map refinement. In the initialization step, a new adaptive-weight model based on the linear support region is put forward for cost aggregation. In this model, the neural network is used to evaluate the spatial proximity, and the mean-shift segmentation method is used to improve the accuracy of color similarity; the Birchfield pixel dissimilarity function and the census transform are adopted to establish the dissimilarity measurement function. Then the initial disparity map is obtained by loopy belief propagation. In the refinement step, the disparity map is optimized by iterative left-right consistency checking method and segmentation voting method. The parameter values involved in this algorithm are determined with many simulation experiments to further improve the matching effect. Simulation results indicate that this new matching method performs well on standard stereo benchmarks and running time of our algorithm is remarkably lower than that of algorithm with rectangle-shaped support region.

  9. Analytical X-ray line profile analysis based upon correlated dislocations

    International Nuclear Information System (INIS)

    Rao, S.; Houska, C.R.

    1988-01-01

    Recent advances describing X-ray line profiles analytically, in terms of a minimum number of parameters, are related to a theory based upon correlated dislocations. It is shown that a multiple convolution approach, based upon the Warren-Averbach (W-A) analysis, leads to a form that closely approximates the strain coefficient obtained by Krivoglaz, Martynenko and Ryaboshopka. This connection enables one to determine the dislocation density and the ratio of the correlation range parameter to the mean particle size. These two results are obtained most accurately from previous analytical approaches which make use of a statistical least-squares analysis. The W-A Fourier-series approach provides redundant information and does not focus on the critical parameters that relate to dislocation theory. Results so far are limited to b.c.c. materials. Results for cold-worked W, Mo, Nb, Cr and V are compared with highly imperfect sputtered films of Mo. A major difference is relatable to higher correlation of dislocations in cold-worked metals than is found in sputtered films deposited at low temperatures. However, in each case, the dislocation density is high. (orig.)

  10. Fast intersection detection algorithm for PC-based robot off-line programming

    Science.gov (United States)

    Fedrowitz, Christian H.

    1994-11-01

    This paper presents a method for fast and reliable collision detection in complex production cells. The algorithm is part of the PC-based robot off-line programming system of the University of Siegen (Ropsus). The method is based on a solid model which is managed by a simplified constructive solid geometry model (CSG-model). The collision detection problem is divided in two steps. In the first step the complexity of the problem is reduced in linear time. In the second step the remaining solids are tested for intersection. For this the Simplex algorithm, which is known from linear optimization, is used. It computes a point which is common to two convex polyhedra. The polyhedra intersect, if such a point exists. Regarding the simplified geometrical model of Ropsus the algorithm runs also in linear time. In conjunction with the first step a resultant collision detection algorithm is found which requires linear time in all. Moreover it computes the resultant intersection polyhedron using the dual transformation.

  11. The Study of Expectations at the University: Analysis of Empirical Works and Future Lines of Investigation

    Directory of Open Access Journals (Sweden)

    María del Carmen Pichardo Martínez

    2007-05-01

    Full Text Available The study of expectations in education has changed in recent years. The new theoretical framework is strongly influenced by research in the field of business, and has attracted increased interest in university expectations as a variable to consider for improving academic quality and student satisfaction. The increase in studies to find out what is expected and what students want from the university, causes the need to analyze the different lines of research pursued in this regard as well as the most significant findings; so as to, starting from here, extract the conclusions that would help develop and move ahead in the study of university students’ expectations. The objective of this work is to make this analysis and provide conclusions that would help establish new lines of research on this topic of study.

  12. Investigation of Orthogonal Frequency Division Multiplexing Based Power Line Communication Systems

    OpenAIRE

    Hosseinpour, Ali

    2015-01-01

    Power Line Communication (PLC) has the potential to become the preferred technique for providing broadband to homes and offices with the advantage of eliminating the need for new wiring infrastructure and reducing the cost. Power line grids, however, present a hostile channel for data communication, since the fundamental purpose of the power line channel was only the transmission of electric power at 50/60 Hz frequencies. The development of PLC systems for providing broadband applications req...

  13. Evidence-based measures to prevent central line-associated bloodstream infections: a systematic review.

    Science.gov (United States)

    Perin, Daniele Cristina; Erdmann, Alacoque Lorenzini; Higashi, Giovana Dorneles Callegaro; Sasso, Grace Teresinha Marcon Dal

    2016-09-01

    to identify evidence-based care to prevent CLABSI among adult patients hospitalized in ICUs. systematic review conducted in the following databases: PubMed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf and Cochrane Studies addressing care and maintenance of central venous catheters, published from January 2011 to July 2014 were searched. The 34 studies identified were organized in an instrument and assessed by using the classification provided by the Joanna Briggs Institute. the studies presented care bundles including elements such as hand hygiene and maximal barrier precautions; multidimensional programs and strategies such as impregnated catheters and bandages and the involvement of facilities in and commitment of staff to preventing infections. care bundles coupled with education and the commitment of both staff and institutions is a strategy that can contribute to decreased rates of central line-associated bloodstream infections among adult patients hospitalized in intensive care units. identificar evidências de cuidados para prevenção de infecção de corrente sanguínea relacionada a cateter venoso central em pacientes adultos em Unidades de Terapia Intensiva. revisão Sistemática realizada por meio de busca nas bases de dados Pubmed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf e Cochrane. Foram buscadas pesquisas com cuidados com a cateterização e manutenção do cateter venoso central, publicados de janeiro de 2011 a julho de 2014. Os 34 estudos incluídos foram organizados em um instrumento e avaliados por meio da classificação do The Joanna Briggs Institute. os estudos apresentaram bundles de cuidados com elementos como a higiene das mãos e precauções máximas de barreira; programas multidimensionais e estratégias como cateteres e curativos impregnados e o envolvimento da instituição e engajamento da equipe nos esforços para prevenção de infecção. os cuidados no formato de bundles aliados com a educação e engajamento da equipe e

  14. Incorporation study of 18FDG through its uptake into tumour-derived cell lines

    International Nuclear Information System (INIS)

    Costa, Flavia M.; Nascimento, Leonardo T.C.; Santos, Raquel G.

    2013-01-01

    In vitro tests of radiopharmaceuticals are an important instrument to study their mechanisms of action, binding and incorporation. 18 FDG is the most used radiopharmaceutical for diagnostics positron emission tomography (PET) on oncology, on the basis of accelerated rates of absorption of glucose in cell malignancies. This radiotracer has been routinely produced at CDTN; and therefore, it was selected for preliminary assays due to its availability. Nowadays, UPPR at CDTN produces routinely 18 FDG for the local PET Centers but others PET radiopharmaceuticals are in development such as 18 F-Fluorocholine and 18 F-Fluorothymidine. According to the Brazilian Health Regulatory Agency (ANVISA) it is necessary to validate and register these new radiopharmaceuticals in order to get the approval for their commercialization. Targeting efficacy is one of the important issues to be evaluated during radiopharmaceutical validation. The aim of this study was to develop a standard protocol to determine tumor targeting efficacy of PET radiopharmaceuticals in vitro. Therefore it was developed a protocol based on the incorporation og 18 FDG through the uptake in different tumor-derived cell lines. Three variables were investigated for the standardization of the test: the number of cells to be seeded in 96-well plates, the time of incubation with the radiopharmaceutical and the radiotracer concentration. The standardized protocol was considered suitable for 18 FDG incorporation assay and showed reproductive results. The protocol developed in this work will pave the way for the in vitro studies of incorporation of the new PET radiopharmaceuticals to be produced at UPPR-CDTN, such as: 18 F-Fluorocholine and 18 F-Fluorothymidine. (author)

  15. Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

    Science.gov (United States)

    Scisciò, M.; Lancia, L.; Migliorati, M.; Mostacci, A.; Palumbo, L.; Papaphilippou, Y.; Antici, P.

    2016-03-01

    In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequency (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupoles and solenoids) as an easy implementable solution when the laser-plasma accelerated beam requires optimization. In this paper, we report on a parametric study related to the transport of electron beams accelerated by laser-plasma interaction, using conventional accelerator elements and tools. We focus on both, high energy electron beams in the GeV range, as produced on petawatt (PW) class laser systems, and on lower energy electron beams in the hundreds of MeV range, as nowadays routinely obtained on commercially available multi-hundred TW laser systems. For both scenarios, our study allows understanding what are the crucial parameters that enable laser-plasma accelerators to compete with conventional ones and allow for a beam transport. We show that suitable working points require a tradeoff-combination between low beam divergence and narrow energy spread.

  16. A Phase II Study of Weekly Docetaxel as Second-Line Chemotherapy in Patients With Metastatic Urothelial Carcinoma.

    Science.gov (United States)

    Kim, Young Saing; Lee, Soon Il; Park, Se Hoon; Park, Silvia; Hwang, In Gyu; Lee, Sang-Cheol; Sun, Jong-Mu; Lee, Jeeyun; Lim, Ho Yeong

    2016-02-01

    The present multicenter phase II study evaluated the efficacy and safety of weekly docetaxel as second-line chemotherapy for metastatic urothelial carcinoma. Weekly docetaxel was well tolerated but demonstrated modest activity, with a response rate of 6%, a median progression-free survival (PFS) of 1.4 months, and a median overall survival (OS) of 8.3 months. The dichotomy between PFS and OS was likely associated with subsequent platinum-based chemotherapy received by 58% of the patients. Docetaxel is commonly used for second-line therapy for metastatic urothelial carcinoma (UC). However, myelosuppression is a substantial concern when the traditional 3-week docetaxel cycle is used. The present multicenter phase II study evaluated the efficacy and safety of weekly docetaxel as second-line chemotherapy for metastatic UC. Patients with progression after previous platinum-based chemotherapy for advanced or metastatic disease were treated with docetaxel 30 mg/m(2) on days 1 and 8 every 21 days. The primary endpoint was the response rate. The study enrolled 31 patients. Their median age was 64 years (range, 40-79 years). An Eastern Cooperative Oncology Group performance status of 1, liver metastasis, and a hemoglobin level chemotherapy had been administered for metastatic disease in 29 patients (94%). Although fatigue (13%) and anorexia (6%) were the most frequently observed grade 3 to 4 toxicities, the safety profiles were generally mild and manageable. Two patients (6%) achieved an objective response, which was maintained for 3.0 to 7.8 months. Eight patients experienced disease stabilization (disease control rate, 32%). The median progression-free survival (PFS) and overall survival (OS) were 1.4 months (95% confidence interval [CI], 1.3-1.6) and 8.3 months (95% CI, 5.9-10.6), respectively. A relatively long OS was associated with further salvage platinum-based chemotherapy (n = 18, 58%) showing an encouraging activity (response rate, 44%; median PFS, 4.0 months

  17. Modeling the Impacts of Climate Change on Phytogeographical Units. A Case Study of the Moesz Line

    OpenAIRE

    Bede-Fazekas, Ákos

    2013-01-01

    Regional climate models (RCMs) provide reliable climatic predictions for the next 90 years with high horizontal and temporal resolution. In the 21st century northward latitudinal and upward altitudinal shift of the distribution of plant species and phytogeographical units is expected. It is discussed how the modeling of phytogeographical unit can be reduced to modeling plant distributions. Predicted shift of the Moesz line is studied as case study (with three different modeling approaches) us...

  18. Study of the behaviour of magnetic lines after perturbation of a toroidal field with magnetic surfaces

    International Nuclear Information System (INIS)

    Mercier, C.

    1989-02-01

    The effect of a perturbing magnetic field on a field whose magnetic surfaces are tori nested around a closed central line is studied. This perturbation effect creates magnetic islands around surfaces with rational rotational transform. These islands are investigated analytically, which makes it possible to evaluate their size. The resulting turbulence of the medium can then be studied by calculating the interaction of two neighbouring islands

  19. Investigation of Genetic Distance among Parental Lines of Hybrid Rice Based on Cluster Analysis of Morphological Traits

    Directory of Open Access Journals (Sweden)

    A. Baluch-Zehi

    2013-06-01

    Full Text Available conditions. Thus, these varieties could be suitable option for yield increase and an effective step toward food security. Selection of parental lines has essential role in developing ideal combinations. Therefore, it is essential to study the relationship and genetic diversity among parental lines in hybrid rice. Sixteen hybrid rice parental lines including 6 restorer lines (Poya, Sepidrud, Pajohesh, R2, R9 and IR50 and 5 CMS lines (Neda, Nemat, Dasht, Champa and Amol 3 with their 5 maintainers were studied at Research Farm of Sari Agricultural Sciences and Natural Resources University during 2011. Analysis of variance showed significant variations for all of the studied traits, which shows great diversity among the genotypes. The number of fertile tillers and length to width ratio of grain showed positive and significant correlation with yield. But, grain width showed negative and significant correlation with yield. Results of principal component analysis revealed that 3 components explained 75.64% of the total variations. Cluster analysis at 15 genetic distance criteria grouped genotypes in 4 clusters. In exploration of heterosis phenomenon, parents must be far away from each other. So, the results of this study suggested crosses between CMS lines of Neda A, Nemat A and Champa A with each of restorer lines R9, R2, IR50 and Poya for experimental hybrid seed production.

  20. Novel Infiltration Diagnostics based on Laser-line Scanning and Infrared Temperature Field Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xinwei [Iowa State Univ., Ames, IA (United States)

    2017-12-08

    This project targets the building energy efficiency problems induced by building infiltration/leaks. The current infiltration inspection techniques often require extensive visual inspection and/or whole building pressure test. These current techniques cannot meet more than three of the below five criteria of ideal infiltration diagnostics: 1. location and extent diagnostics, 2. building-level application, 3. least surface preparation, 4. weather-proof, and 5. non-disruption to building occupants. These techniques are either too expensive or time consuming, and often lack accuracy and repeatability. They are hardly applicable to facades/facades section. The goal of the project was to develop a novel infiltration diagnostics technology based on laser line-scanning and simultaneous infrared temperature imaging. A laboratory scale experimental setup was designed to mimic a model house of well-defined pressure difference below or above the outside pressure. Algorithms and Matlab-based programs had been developed for recognition of the hole location in infrared images. Our experiment based on laser wavelengths of 450 and 1550 nm and laser beam diameters of 4-25 mm showed that the location of the holes could be identified using laser heating; the diagnostic approach however could not readily distinguish between infiltration and non-infiltration points. To significantly improve the scanning throughput and recognition accuracy, a second approach was explored, developed, and extensively tested. It incorporates a liquid spray on the surface to induce extra phase change cooling effect. In this spray method, we termed it as PECIT (Phase-change Enhanced Cooling Infrared Thermography), phase-change enhanced cooling was used, which significantly amplifies the effect of air flow (infiltration and exfiltration). This heat transfer method worked extremely well to identify infiltration and exfiltration locations with high accuracy and increased throughput. The PECIT technique was

  1. Rigorous Line-Based Transformation Model Using the Generalized Point Strategy for the Rectification of High Resolution Satellite Imagery

    Directory of Open Access Journals (Sweden)

    Kun Hu

    2016-09-01

    Full Text Available High precision geometric rectification of High Resolution Satellite Imagery (HRSI is the basis of digital mapping and Three-Dimensional (3D modeling. Taking advantage of line features as basic geometric control conditions instead of control points, the Line-Based Transformation Model (LBTM provides a practical and efficient way of image rectification. It is competent to build the mathematical relationship between image space and the corresponding object space accurately, while it reduces the workloads of ground control and feature recognition dramatically. Based on generalization and the analysis of existing LBTMs, a novel rigorous LBTM is proposed in this paper, which can further eliminate the geometric deformation caused by sensor inclination and terrain variation. This improved nonlinear LBTM is constructed based on a generalized point strategy and resolved by least squares overall adjustment. Geo-positioning accuracy experiments with IKONOS, GeoEye-1 and ZiYuan-3 satellite imagery are performed to compare rigorous LBTM with other relevant line-based and point-based transformation models. Both theoretic analysis and experimental results demonstrate that the rigorous LBTM is more accurate and reliable without adding extra ground control. The geo-positioning accuracy of satellite imagery rectified by rigorous LBTM can reach about one pixel with eight control lines and can be further improved by optimizing the horizontal and vertical distribution of control lines.

  2. Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

    Directory of Open Access Journals (Sweden)

    Roger T. Engeli

    2018-02-01

    Full Text Available Androgen biosynthesis in males occurs to a large extent in testicular Leydig cells. This study focused on the evaluation of three murine Leydig cell lines as potential screening tool to test xenobiotics interfering with gonadal androgen synthesis. The final step of testosterone (T production in Leydig cells is catalyzed by the enzyme 17β-hydroxysteroid dehydrogenase 3 (17β-hsd3. The endogenous 17β-hsd3 mRNA expression and Δ4-androstene-3,17-dione (AD to T conversion were determined in the murine cell lines MA-10, BLTK1 and TM3. Additionally, effects of 8-Br-cAMP and forskolin stimulation on steroidogenesis and T production were analyzed. Steroids were quantified in supernatants of cells using liquid chromatography–tandem mass spectrometry. Unstimulated cells incubated with AD produced only very low T but substantial amounts of the inactive androsterone. Stimulated cells produced low amounts of T, moderate amounts of AD, but high amounts of progesterone. Gene expression analyses revealed barely detectable 17β-hsd3 levels, absence of 17β-hsd5 (Akr1c6, but substantial 17β-hsd1 expression in all three cell lines. Thus, MA-10, BLTK1 and TM3 cells are not suitable to study the expression and activity of the gonadal T synthesizing enzyme 17β-hsd3. The low T production reported in stimulated MA-10 cells are likely a result of the expression of 17β-hsd1. This study substantiates that the investigated Leydig cell lines MA-10, BLTK1, and TM3 are not suitable to study gonadal androgen biosynthesis due to altered steroidogenic pathways. Furthermore, this study emphasizes the necessity of mass spectrometry-based steroid quantification in experiments using steroidogenic cells such as Leydig cells.

  3. Frequency domain analysis of the lightning current distribution to ground at the transmission line tower with cellular phone base station

    NARCIS (Netherlands)

    Grcev, L.; Deursen, van A.P.J.; Waes, van J.B.M.

    2003-01-01

    Cellular phone base stations are often placed in the poles of power transmission lines. We consider the case when such base stations are powered from the low-voltage network. Of special concern is the current that might be led through the cable metallic shields to other customers' premises in case

  4. Image registration algorithm for high-voltage electric power live line working robot based on binocular vision

    Science.gov (United States)

    Li, Chengqi; Ren, Zhigang; Yang, Bo; An, Qinghao; Yu, Xiangru; Li, Jinping

    2017-12-01

    In the process of dismounting and assembling the drop switch for the high-voltage electric power live line working (EPL2W) robot, one of the key problems is the precision of positioning for manipulators, gripper and the bolts used to fix drop switch. To solve it, we study the binocular vision system theory of the robot and the characteristic of dismounting and assembling drop switch. We propose a coarse-to-fine image registration algorithm based on image correlation, which can improve the positioning precision of manipulators and bolt significantly. The algorithm performs the following three steps: firstly, the target points are marked respectively in the right and left visions, and then the system judges whether the target point in right vision can satisfy the lowest registration accuracy by using the similarity of target points' backgrounds in right and left visions, this is a typical coarse-to-fine strategy; secondly, the system calculates the epipolar line, and then the regional sequence existing matching points is generated according to neighborhood of epipolar line, the optimal matching image is confirmed by calculating the similarity between template image in left vision and the region in regional sequence according to correlation matching; finally, the precise coordinates of target points in right and left visions are calculated according to the optimal matching image. The experiment results indicate that the positioning accuracy of image coordinate is within 2 pixels, the positioning accuracy in the world coordinate system is within 3 mm, the positioning accuracy of binocular vision satisfies the requirement dismounting and assembling the drop switch.

  5. Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines

    Directory of Open Access Journals (Sweden)

    Travert Carine

    2010-10-01

    Full Text Available Abstract Background Worldwide used pesticides containing different adjuvants like Roundup formulations, which are glyphosate-based herbicides, can provoke some in vivo toxicity and in human cells. These pesticides are commonly found in the environment, surface waters and as food residues of Roundup tolerant genetically modified plants. In order to know their effects on cells from liver, a major detoxification organ, we have studied their mechanism of action and possible protection by precise medicinal plant extracts called Dig1. Methods The cytotoxicity pathways of four formulations of glyphosate-based herbicides were studied using human hepatic cell lines HepG2 and Hep3B, known models to study xenobiotic effects. We monitored mitochondrial succinate dehydrogenase activity and caspases 3/7 for cell mortality and protection by Dig1, as well as cytochromes P450 1A1, 1A2, 3A4 and 2C9 and glutathione-S-transferase to approach the mechanism of actions. Results All the four Roundup formulations provoke liver cell death, with adjuvants having stronger effects than glyphosate alone. Hep3B are 3-5 times more sensitive over 48 h. Caspases 3/7 are greatly activated in HepG2 by Roundup at non-cytotoxic levels, and some apoptosis induction by Roundup is possible together with necrosis. CYP3A4 is specifically enhanced by Roundup at doses 400 times less than used in agriculture (2%. CYP1A2 is increased to a lesser extent together with glutathione-S-transferase (GST down-regulation. Dig 1, non cytotoxic and not inducing caspases by itself, is able to prevent Roundup-induced cell death in a time-dependant manner with an important efficiency of up to 89%, within 48 h. In addition, we evidenced that it prevents Caspases 3/7 activation and CYP3A4 enhancement, and not GST reduction, but in turn it slightly inhibited CYP2C9 when added before Roundup. Conclusion Roundup is able to provoke intracellular disruption in hepatic cell lines at different levels, but a

  6. A study of parallelism of the occlusal plane and ala-tragus line.

    Science.gov (United States)

    Sadr, Katayoun; Sadr, Makan

    2009-01-01

    Orientation of the occlusal plane is one of the most important clinical procedures in prostho-dontic rehabilitation of edentulous patients. The aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. Fifty-three dental students (27 females and 26 males) with complete natural dentition and Angel's Class I occlusal relationship were selected. The subjects were photographed in natural head position while clenching on a Fox plane. After tracing the photographs, the angles between the following lines were measured: the occlusal plane (Fox plane) and the superior border of ala-tragus, the occlusal plane (Fox plane) and the middle of ala-tragus as well as the occlusal plane (Fox plane) and the inferior border of ala-tragus. Descriptive statistics, one sample t-test and independent t-test were used. P value less than 0.05 was considered significant. There was no parallelism between the occlusal plane and ala-tragus line with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (pplane. The superior border of the tragus is suggested as the posterior reference for ala-tragus line.

  7. High efficiency and flexible working distance digital in-line holographic microscopy based on Fresnel zone plate

    International Nuclear Information System (INIS)

    Tian, Peng; Yang, Fan; Li, Fanxing; Hu, Song; Yan, Wei; Hua, Yilei

    2017-01-01

    Traditional digital in-line holography suffers from twin-image noise problems and extremely short working distances between the object and light source. Here, we propose lensless Fourier transform digital in-line holographic microscopy based on a single optical element. A Fresnel zone plate is used to split the incident light into two parts: one is scattered along the original direction, the other is gathered at a focal point and the sample is put behind the focus. The interference fringe pattern, formed by the two beams, is recorded digitally by a CCD camera. A novel reconstruction algorithm is proposed to present the object image. The proof-of-concept experiments demonstrate that the proposed technique can eliminate the twin-image noise problem, improving the image contrast with high efficiency, and increasing the flexibility of the working distance. Furthermore, a wide field of view and no contact make it a promising tool for the study of materials science, biology and microelectronics. (paper)

  8. Analyze On-line Star Economy Basing on Models of Entrepreneurship

    Institute of Scientific and Technical Information of China (English)

    胡志豪

    2016-01-01

    The outstanding performance of the On-line Star Economy is bound up with social media and promotion by fans, stimulating a new round of consumption upgrading and capital tendency. There is no denying that the On-line Star Economy may be the fortuitous outcome of the times. But the fact remains it can be analyzed rationally using Models of Entrepreneurship.

  9. An applied optimization based method for line planning to minimize travel time

    DEFF Research Database (Denmark)

    Bull, Simon Henry; Rezanova, Natalia Jurjevna; Lusby, Richard Martin

    The line planning problem in rail is to select a number of lines froma potential pool which provides sufficient passenger capacity and meetsoperational requirements, with some objective measure of solution linequality. We model the problem of minimizing the average passenger systemtime, including...

  10. Genomic prediction based on data from three layer lines: a comparison between linear methods

    NARCIS (Netherlands)

    Calus, M.P.L.; Huang, H.; Vereijken, J.; Visscher, J.; Napel, ten J.; Windig, J.J.

    2014-01-01

    Background The prediction accuracy of several linear genomic prediction models, which have previously been used for within-line genomic prediction, was evaluated for multi-line genomic prediction. Methods Compared to a conventional BLUP (best linear unbiased prediction) model using pedigree data, we

  11. Improving the output voltage waveform of an intense electron-beam accelerator based on helical type Blumlein pulse forming line

    Directory of Open Access Journals (Sweden)

    Xin-Bing Cheng

    2010-07-01

    Full Text Available The Blumlein pulse forming line (BPFL consisting of an inner coaxial pulse forming line (PFL and an outer coaxial PFL is widely used in the field of pulsed power, especially for intense electron-beam accelerators (IEBA. The output voltage waveform determines the quality and characteristics of the output beam current of the IEBA. Comparing with the conventional BPFL, an IEBA based on a helical type BPFL can increase the duration of the output voltage in the same geometrical volume. However, for the helical type BPFL, the voltage waveform on a matched load may be distorted which influences the electron-beam quality. In this paper, an IEBA based on helical type BPFL is studied theoretically. Based on telegrapher equations of the BPFL, a formula for the output voltage of IEBA is obtained when the transition section is taken into account, where the transition section is between the middle cylinder of BPFL and the load. From the theoretical analysis, it is found that the wave impedance and transit time of the transition section influence considerably the main pulse voltage waveform at the load, a step is formed in front of the main pulse, and a sharp spike is also formed at the end of the main pulse. In order to get a well-shaped square waveform at the load and to improve the electron-beam quality of such an accelerator, the wave impedance of the transition section should be equal to that of the inner PFL of helical type BPFL and the transit time of the transition section should be designed as short as possible. Experiments performed on an IEBA with the helical type BPFL show reasonable agreement with theoretical analysis.

  12. CALCULATION METHOD OF ELECTRIC POWER LINES MAGNETIC FIELD STRENGTH BASED ON CYLINDRICAL SPATIAL HARMONICS

    Directory of Open Access Journals (Sweden)

    A.V. Erisov

    2016-05-01

    Full Text Available Purpose. Simplification of accounting ratio to determine the magnetic field strength of electric power lines, and assessment of their environmental safety. Methodology. Description of the transmission lines of the magnetic field by using techniques of spatial harmonic analysis in the cylindrical coordinate system is carried out. Results. For engineering calculations of electric power lines magnetic field with sufficient accuracy describes their first spatial harmonic magnetic field. Originality. Substantial simplification of the definition of the impact of the construction of transmission line poles on the value of its magnetic field and the bands of land alienation sizes. Practical value. The environmentally friendly projection electric power lines on the level of the magnetic field.

  13. A liquid lens switching-based motionless variable fiber-optic delay line

    Science.gov (United States)

    Khwaja, Tariq Shamim; Reza, Syed Azer; Sheikh, Mumtaz

    2018-05-01

    We present a Variable Fiber-Optic Delay Line (VFODL) module capable of imparting long variable delays by switching an input optical/RF signal between Single Mode Fiber (SMF) patch cords of different lengths through a pair of Electronically Controlled Tunable Lenses (ECTLs) resulting in a polarization-independent operation. Depending on intended application, the lengths of the SMFs can be chosen accordingly to achieve the desired VFODL operation dynamic range. If so desired, the state of the input signal polarization can be preserved with the use of commercially available polarization-independent ECTLs along with polarization-maintaining SMFs (PM-SMFs), resulting in an output polarization that is identical to the input. An ECTL-based design also improves power consumption and repeatability. The delay switching mechanism is electronically-controlled, involves no bulk moving parts, and can be fully-automated. The VFODL module is compact due to the use of small optical components and SMFs that can be packaged compactly.

  14. EnviroNET: An on-line environment data base for LDEF data

    Science.gov (United States)

    Lauriente, Michael

    1992-01-01

    EnviroNET is an on-line, free form data base intended to provide a centralized depository for a wide range of technical information on environmentally induced interactions of use to Space Shuttle customers and spacecraft designers. It provides a user friendly, menu driven format on networks that are connected globally and is available twenty-four hours a day, every day. The information updated regularly, includes expository text, tabular numerical data, charts and graphs, and models. The system pools space data collected over the years by NASA, USAF, other government facilities, industry, universities, and ESA. The models accept parameter input from the user and calculate and display the derived values corresponding to that input. In addition to the archive, interactive graphics programs are also available on space debris, the neutral atmosphere, radiation, magnetic field, and ionosphere. A user friendly informative interface is standard for all the models with a pop-up window, help window with information on inputs, outputs, and caveats. The system will eventually simplify mission analysis with analytical tools and deliver solution for computational intense graphical applications to do 'What if' scenarios. A proposed plan for developing a repository of LDEF information for a user group concludes the presentation.

  15. Slit shaped microwave induced atmospheric pressure plasma based on a parallel plate transmission line resonator

    Science.gov (United States)

    Kang, S. K.; Seo, Y. S.; Lee, H. Wk; Aman-ur-Rehman; Kim, G. C.; Lee, J. K.

    2011-11-01

    A new type of microwave-excited atmospheric pressure plasma source, based on the principle of parallel plate transmission line resonator, is developed for the treatment of large areas in biomedical applications such as skin treatment and wound healing. A stable plasma of 20 mm width is sustained by a small microwave power source operated at a frequency of 700 MHz and a gas flow rate of 0.9 slm. Plasma impedance and plasma density of this plasma source are estimated by fitting the calculated reflection coefficient to the measured one. The estimated plasma impedance shows a decreasing trend while estimated plasma density shows an increasing trend with the increase in the input power. Plasma uniformity is confirmed by temperature and optical emission distribution measurements. Plasma temperature is sustained at less than 40 °C and abundant amounts of reactive species, which are important agents for bacteria inactivation, are detected over the entire plasma region. Large area treatment ability of this newly developed device is verified through bacteria inactivation experiment using E. coli. Sterilization experiment shows a large bacterial killing mark of 25 mm for a plasma treatment time of 10 s.

  16. Prediction of line failure fault based on weighted fuzzy dynamic clustering and improved relational analysis

    Science.gov (United States)

    Meng, Xiaocheng; Che, Renfei; Gao, Shi; He, Juntao

    2018-04-01

    With the advent of large data age, power system research has entered a new stage. At present, the main application of large data in the power system is the early warning analysis of the power equipment, that is, by collecting the relevant historical fault data information, the system security is improved by predicting the early warning and failure rate of different kinds of equipment under certain relational factors. In this paper, a method of line failure rate warning is proposed. Firstly, fuzzy dynamic clustering is carried out based on the collected historical information. Considering the imbalance between the attributes, the coefficient of variation is given to the corresponding weights. And then use the weighted fuzzy clustering to deal with the data more effectively. Then, by analyzing the basic idea and basic properties of the relational analysis model theory, the gray relational model is improved by combining the slope and the Deng model. And the incremental composition and composition of the two sequences are also considered to the gray relational model to obtain the gray relational degree between the various samples. The failure rate is predicted according to the principle of weighting. Finally, the concrete process is expounded by an example, and the validity and superiority of the proposed method are verified.

  17. MEMS based monolithic Phased array using 3-bit Switched-line Phase Shifter

    Directory of Open Access Journals (Sweden)

    A. Karmakr

    2017-10-01

    Full Text Available This article details the design of an electronically scanning phased array antenna with proposed fabrication process steps. Structure is based upon RF micro-electromechanical system (MEMS technology. Capacitive type shunt switches have been implemented here to cater high frequency operation. The architecture, which is deigned at 30 GHz, consists of 3-bit (11.25º, 22.5º and 45º integrated Switched-line phase shifter and a linearly polarized microstrip patch antenna. Detailed design tricks of the Ka-band phase shifter is outlined here. The whole design is targeted for future monolithic integration. So, the substrate of choice is High Resistive Silicon (ρ > 8kΩ-cm, tan δ =0.01 and ϵr =11.8. The overall circuit occupies an cross-sectional area of 20 × 5 mm2. The simulated results show that the phase shifter can provide nearly 11.25º/22.5º/45º phase shifts and their combinations at the expense of 1dB average insertion loss at 30 GHz for eight combinations. Practical fabrication process flow using surface micromachining is proposed here. Critical dimensions of the phased array structure is governed by the deign rules of the standard CMOS/MEMS foundry.

  18. Productivity improvement in the production line with lean manufacturing approach: case study PT. XYZ

    Directory of Open Access Journals (Sweden)

    diah Halimatussa’

    2018-01-01

    Full Text Available The increaseing productivity is one of the competitive strategies that can be applied in a company in order to survive in an intense competitive presure. PT. XYZ is a textile industry manufacturing golf gloves and caddy bag. Every day, the company has a production target of 600 pieces per line. However, the desired target is not achieved that it will affect the delay in delivery of products to customers. In this research, a case study on implementing value stream mapping and Kaizen as the lean manufacturing concept is reported. The purpose of this study is to map the current production line, analyse and design the future value stream mapping by eliminating waste occured. It is obtained a lead time reduction as much as 440.4 seconds through eliminating 17 non-value added activities. Then, the output can be increased up to 21% which is equal to 502 pieces.

  19. Gaseous microemboli in a pediatric bypass circuit with an unprimed venous line: an in vitro study.

    Science.gov (United States)

    Hudacko, Andrea; Sievert, Alicia; Sistino, Joseph

    2009-09-01

    Miniaturizing cardiopulmonary bypass (CPB) circuits to reduce hemodilution and allogenic blood product administration is common in cardiac surgery. One major concern associated with smaller CPB circuits is a possible increase in gaseous microemboli (GME) sent to the cerebral vasculature, which is exacerbated by vacuum-assisted venous drainage (VAVD). The use of VAVD has increased with smaller venous line diameter and venous cannulae. This study examines the effects of CPB initiation with an unprimed venous line and VAVD in a pediatric circuit. A CPB circuit was set up with reservoir, oxygenator, and arterial filter with a bag reservoir to simulate the patient. All trials were done in vitro, and GME were measured using the EDAC Quantifier by Luna Innovations. EDAC sensors were placed proximal and distal to the oxygenator and distal to the arterial filter. Group 1 was the control group with no VAVD and a primed venous line. Groups 2, 3, and 4 used an unprimed venous line and VAVD of -40, -20, and -10 mmHg, respectively. Total microemboli counts and total embolic load in micrometers were measured at each sensor. Groups 2 (12,379.00 +/- 3180.37) and 3 (8296.67 +/- 2818.76) had significantly more microemboli than group 1 (923.33 +/- 796.08, p sensor. Group 2 (57.33 +/- 25.01, p sensor. No other findings were statistically significant. The results suggest that, if an oxygenator and arterial filter with sufficient air handling capabilities are used, this method to reduce prime volume may not increase GME in the arterial line distal to the arterial filter.

  20. A study on the radiopacity of cavity lining materials for posterior composite resin restoration

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Joo Hoon [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Chosun University, Kwangju (Korea, Republic of); Choi, Eui Hwan [Dept. of Conservative Dentistry, College of Dentistry, Chosun University, Kwangju (Korea, Republic of)

    2000-12-15

    The aim of this study was to determine the relative radiopacities of cavity lining materials (Resin-modified Glass Ionomer cement, Compomer and Flowable resin) for posterior composite resin restoration. Resin-modified glass ionomer cement (Fuji II LC, Vitrebond (TM)), Compomers (Dyract , Compoglass, F2000, Dyract(R) flow Compoglass Flow) and Flowable resins (Tetric (R) flow, Aeliteflo (TM) Revolution (TM)) were used. Five specimens of 5 mm in diameter and 2 mm thick were fabricated with each material. Human molars were horizontally sectioned 2 mm thick to include both enamel and dentin. The radiopacities of enamel, dentin, cavity lining materials, aluminum step wedge were obtained from conventional radiograph and NIH image program. All the tested lining materials showed levels of radiopacity the same as or greater than that of dentin. All compomer tested (Dyract (R), Compoglass, F2000, Dyract (R) flow, Compoglass Flow) and Vitrebond (TM), Tetric (R) flow were more radiopaque than enamel. The radiopacities of Fuji II LC and Revolution (TM) were between enamel and dentin and resin-modified glass ionomer cement, Compomer and Tetric (R) flow were greater than those of Revolution (TM), Aeliteflo (TM) or dentin. The level of radiopacity of the tested materials was variable; those with low radiopacity should be avoided in class II restorations, where a clear determination of recurrent caries by the examining clinician could be compromised. Clinician should be able to distinguish these cavity lining materials radiographically from recurrent decay, voids, gaps, or other defects that lead to clinical failure. Utilization of materials ranked more radiopaque than enamel would enable clinicians to distinguish the lining material from tooth structure.

  1. A study on the radiopacity of cavity lining materials for posterior composite resin restoration

    International Nuclear Information System (INIS)

    Moon, Joo Hoon; Choi, Eui Hwan

    2000-01-01

    The aim of this study was to determine the relative radiopacities of cavity lining materials (Resin-modified Glass Ionomer cement, Compomer and Flowable resin) for posterior composite resin restoration. Resin-modified glass ionomer cement (Fuji II LC, Vitrebond (TM)), Compomers (Dyract , Compoglass, F2000, Dyract(R) flow Compoglass Flow) and Flowable resins (Tetric (R) flow, Aeliteflo (TM) Revolution (TM)) were used. Five specimens of 5 mm in diameter and 2 mm thick were fabricated with each material. Human molars were horizontally sectioned 2 mm thick to include both enamel and dentin. The radiopacities of enamel, dentin, cavity lining materials, aluminum step wedge were obtained from conventional radiograph and NIH image program. All the tested lining materials showed levels of radiopacity the same as or greater than that of dentin. All compomer tested (Dyract (R), Compoglass, F2000, Dyract (R) flow, Compoglass Flow) and Vitrebond (TM), Tetric (R) flow were more radiopaque than enamel. The radiopacities of Fuji II LC and Revolution (TM) were between enamel and dentin and resin-modified glass ionomer cement, Compomer and Tetric (R) flow were greater than those of Revolution (TM), Aeliteflo (TM) or dentin. The level of radiopacity of the tested materials was variable; those with low radiopacity should be avoided in class II restorations, where a clear determination of recurrent caries by the examining clinician could be compromised. Clinician should be able to distinguish these cavity lining materials radiographically from recurrent decay, voids, gaps, or other defects that lead to clinical failure. Utilization of materials ranked more radiopaque than enamel would enable clinicians to distinguish the lining material from tooth structure.

  2. Off-Line and Dynamic Production Scheduling – A Comparative Case Study

    OpenAIRE

    Bożek Andrzej; Wysocki Marian

    2016-01-01

    A comprehensive case study of manufacturing scheduling solutions development is given. It includes highly generalized scheduling problem as well as a few scheduling modes, methods and problem models. The considered problem combines flexible job shop structure, lot streaming with variable sublots, transport times, setup times, and machine calendars. Tabu search metaheuristic and constraint programming methods have been used for the off-line scheduling. Two dynamic scheduling methods have also ...

  3. IN VITRO CYTOTOXICITY STUDY OF AGAVE AMERICANA, STRYCHNOS NUX-VOMICA AND ARECA CATECHU EXTRACTS USING MCF-7 CELL LINE

    Directory of Open Access Journals (Sweden)

    Anajwala Chetan C.

    2010-06-01

    Full Text Available Research is focusing on the search for new types of natural chemotherapeutic agent that is plant based medicines which are proving to be excellent sources of new compounds. In present research study, an attempt was made to prove cytotoxicity activity of various parts of medicinal plants such as Agave americana, Strychnos nux-vomica and Areca catechu using MCF-7 and Vero cell line. Various parts of the medicinal plants were extracted by soxhlet apparatus using solvents likes methanol and water. By trypan blue dye exclusion method, Viability of MCF-7 and Vero cell lines were 85.50 and 81.13%, respectively. IC50 value of methanol extract of Agave americana leaves and aqueous extract of Areca catechu fruits were found to be 545.9 & 826.1 µg/ml by SRB assay and 775.1 & 1461µg/ml by MTT assay, respectively, against MCF-7 cell line. From cytotoxicity study data by SRB and MTT assay, it revealed that methanol extract of Agave americana and aqueous extract of Areca catechu are potent cytotoxic.

  4. Structural evaluation method study and procedure development for pressurizer surge line subjected to thermal stratification phenomenon

    International Nuclear Information System (INIS)

    Zhang Yixiong; Yu Xiaofei; Ai Honglei

    2014-01-01

    Thermal stratification phenomenon of pressurizer surge line can lead potential threaten to plant safety. Base on the mechanism of thermal stratification occurrence, Fr number is used to judge whether the stratification occurs or not. Also the method of calculating heat transfer coefficient is investigated. Theoretically the 3-dimension thermal stress induced by thermal stratification is decoupled to 1-dimension global stress and 2-dimension local stress, and the complex 3-dimension problem is simplified into a combination of 1-dimension and 2-dimension to compute the stress. Comply with criterion RCC-M, the complete structure integrity evaluation is accomplished after combining the stress produced by thermal stratification and the stresses produced by the other loadings. In order to match the above combined analysis method, Code SYSTUS and ROCOCO are developed. By means of aforesaid evaluation method and corresponding analysis program, surge line thermal stratification of Qinshan Phase II Extension project is investigated in this paper. And the results show that structural integrity of the pressurizer surge line affected by thermal stratification still satisfies criterion RCC-M. (authors)

  5. A surface acoustic wave electric field strength meter for environmental studies of HV transmission lines

    International Nuclear Information System (INIS)

    Grandolfo, M.; Ranghiasci, C.; Verona, E.

    1988-01-01

    In recent years, there has been a significant increase in concern over the health and safety aspects of high voltage transmission lines (HVTL). The majority of research has focused on effects directly or indirectly involved with the central nervous system, including physiological, ultrastructural, and biochemical alterations, changes in blood composition, behaviour, reproduction, and development. Several recent epidemiological reports have presented preliminary data suggesting an increase in the incidence of cancer among children and adults exposed to magnetic fields through living close to various types of electrical power lines or devices. With the increase in environmental concerns there has been a concomitant consideration of biological effects and health implications related to presently existing HVTL and those planned in the future. It was concluded that the electric and magnetic field strengths and the electrical discharges are the most important electrophysical factors. Thus, it has been deemed necessary to develop measuring means to determine the field strengths in areas surrounding electric installations, in particular at ground level. In the present paper an electric field meter, based on the use of a surface acoustic wave (SAW) delay line, is presented and the experimental results obtained are discussed

  6. Enhanced detection and study of murine norovirus-1 using a more efficient microglial cell line

    Directory of Open Access Journals (Sweden)

    Lu Yuanan

    2009-11-01

    Full Text Available Abstract Background Human Noroviruses are the predominant cause of non-bacterial gastroenteritis worldwide. To facilitate prevention and control, a norovirus isolated from mice can provide a model to understand human noroviruses. To establish optimal viral infectivity conditions for murine noroviruses, several cell lines of hematopoietic lineage, including murine BV-2, RAW 264.7, and TIB, as well as human CHME-5, were tested comparatively for their sensitivity to murine norovirus-1. Results Except for CHME-5, all three murine-derived cell lines were susceptible to MNV infection. Viral infection of these cells was confirmed by RT-PCR. Using both viral plaque and replication assays, BV-2 and RAW 264.7 cells were determined to have comparable sensitivities to MNV-1 infection. Comparisons of cell growth characteristics, general laboratory handling and potential in-field applications suggest the use of BV-2 to be more advantageous. Conclusion Results obtained from these studies demonstrate that an immortalized microglial cell line can support MNV-1 replication and provides a more efficient method to detect and study murine noroviruses, facilitating future investigations using MNV-1 as a model to study, detect, and control Human Norovirus.

  7. In vitro incorporation studies of 99mTc-alendronate sodium at different bone cell lines

    International Nuclear Information System (INIS)

    Evren Gundogdu; Derya Ilem-Ozdemir; Makbule Asikoglu

    2014-01-01

    Bisphosphonates can be labeled with Technetium-99m ( 99m Tc) and are used for bone imaging because of their good localization in the skeleton and rapid clearance from soft tissues. Over the last decades bone scintigraphy has been used extensively in the evaluation of oncological patients to provide information about the sites of bone lesions, their prognosis and the effectiveness of therapy by showing the sequential changes in tracer uptake. Since the lesion visualization and lesion/bone ratio are important utilities for a bone scanning radiopharmaceutic; in this study incorporation of 99m Tc labeled alendronate sodium ( 99m Tc-ALD) was evaluated in U 2 OS (human bone osteosarcoma) and NCI-H209 (human bone carcinoma) cell lines. ALD was directly labeled by 99m Tc, radiochemical purity and stability of the complex were analyzed by radioactive thin layer chromatography and radioactive high performance liquid chromatography studies. For cell incorporation study, NCI-H209 and U 2 OS cell lines were used with standard cell culture methods. The six well plates were used for all experiments and the integrity of each cell monolayer was checked by measuring its transepithelial electrical resistance (TEER) with an epithelial voltammeter. Results confirmed that ALD was successfully radiolabeled with 99m Tc. 99m Tc-ALD incorporated with NCI-H209 and U 2 OS cells. The uptake percentages of 99m Tc-ALD in NCI-H209 and U 2 OS cell lines were found significantly different. Since 99m Tc-ALD highly uptake in cancer cell line, the results demonstrated that radiolabeled ALD may be a promising agent for bone cancer diagnosis. (author)

  8. An In Vivo Evaluation of the Fit of Zirconium-Oxide Based, Ceramic Single Crowns with Vertical and Horizontal Finish Line Preparations.

    Science.gov (United States)

    Vigolo, Paolo; Mutinelli, Sabrina; Biscaro, Leonello; Stellini, Edoardo

    2015-12-01

    Different types of tooth preparations influence the marginal precision of zirconium-oxide based ceramic single crowns. In this in vivo study, the marginal fits of zirconium-oxide based ceramic single crowns with vertical and horizontal finish lines were compared. Forty-six teeth were chosen in eight patients indicated for extraction for implant placement. CAD/CAM technology was used for the production of 46 zirconium-oxide-based ceramic single crowns: 23 teeth were prepared with vertical finishing lines, 23 with horizontal finishing lines. One operator accomplished all clinical procedures. The zirconia crowns were cemented with glass ionomer cement. The teeth were extracted 1 month later. Marginal gaps along vertical planes were measured for each crown, using a total of four landmarks for each tooth by means of a microscope at 50× magnification. On conclusion of microscopic assessment, ESEM evaluation was completed on all specimens. The comparison of the gap between the two types of preparation was performed with a nonparametric test (two-sample Wilcoxon rank-sum test) with a level of significance fixed at p zirconium-oxide-based ceramic CAD/CAM crowns with vertical and horizontal finish line preparations were not different. © 2015 by the American College of Prosthodontists.

  9. Identification of Variables and Factors Impacting Consumer Behavior in On-line Shopping in India: An Empirical Study

    Science.gov (United States)

    Chhikara, Sudesh

    On-line shopping is a recent phenomenon in the field of E-Business and is definitely going to be the future of shopping in the world. Most of the companies are running their on-line portals to sell their products/services. Though online shopping is very common outside India, its growth in Indian Market, which is a large and strategic consumer market, is still not in line with the global market. The potential growth of on-line shopping has triggered the idea of conducting a study on on-line shopping in India. The present research paper has used exploratory study to depict and highlight the various categories of factors and variables impacting the behavior of consumers towards on-line shopping in India. The data was collected through in-depth interviews on a sample of 41 respondents from Delhi, Mumbai, Chennai and Bangalore. The results of the study show that on-line shopping in India is basically impacted by five categories of factors like demographics factor, Psychographics factor, Online shopping feature and policies, Technological factor, Security factor. The results of the study are used to present a comprehensive model of on-line shopping which could be further used by the researchers and practitioners for conducting future studies in the similar area. A brief operational definition of all the factors and variables impacting on-line shopping in India is also described. And finally practical implications of the study are also elucidated.

  10. Synchrotron X-Ray Microdiffraction Studies of Electromigration in Interconnect lines at the Advanced Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Tamura, Nobumichi; Chen, Kai; Kunz, Martin

    2009-12-01

    Synchrotron polychromatic X-ray microdiffraction is a particularly suitable technique to study in situ the effect of electromigration in metal interconnects as add spatial resolution to grain orientation and strain sensitivity. This technique has been extensively used at the Advanced Light Source to monitor changes in aluminum and copper interconnect test structures while high-density current is passed into them during accelerated tests at elevated temperature. One of the principal findings is the observation of electromigration-induced plasticity in the metal lines that appear during the very early stages of electromigration. In some of the lines, high density of geometrically necessary dislocation are formed leading to additional diffusion paths causing an enhancement of electromigration effect at test temperature.

  11. Study for reactive power on distribution system line B RSG-GAS

    International Nuclear Information System (INIS)

    Yan Bony Marsahala

    2010-01-01

    Study for reactive power on distribution system line B RSG-GA is already done. The study intended to evaluate how much inductive load need the reactive power (positive), how much power factor, and what will be done to increase the power factor. The reactive power is the losses power, can't be changed into energy, but it is need for transmission process and it is cause the energy losses. The loads on distribution system line B consist of induction motors which are used for primary cooling system and secondary cooling system, lift, blower on cooling tower, and air condition system. Due to the motors using, the power factor are falling down to low. By the calculation results give that the inductive loads on distribution line B are 850 KVA and these loads caused the low power factor 0.80. If we want to increase the power factor up to 0.95, it is need to install the reactive loads likes capacitor bank 250 KVAR. (author)

  12. Final report on fiscal year 1992 activities for the environmental monitors line-loss study

    International Nuclear Information System (INIS)

    Kenoyer, J.L.

    1993-01-01

    The work performed on this Environmental Monitors Line-Loss Study has been performed under Contract Numbers MLW-SVV-073750 and MFH-SVV-207554. Work on the task was initiated mid-December 1991, and this report documents and summarizes the work performed through January 18, 1993. The sections included in this report summarize the work performed on the Environmental Monitors Line-Loss Study. The sections included in this report are arranged to reflect individual sub-tasks and include: descriptions of measurement systems and procedures used to obtain cascade impactor samples and laser spectrometer measurements from multiple stacks and locations; information on data acquisition, analyses, assessment, and software; discussion of the analyses and measurement results from the cascade impactor and laser spectrometer systems and software used; discussion on the development of general test methods and procedures for line-loss determinations; an overall summary and specific conclusions that can be made with regard to efforts performed on this task during FY 1992 and FY 1993. Supporting information for these sections is included in this report as appendices

  13. TIGER/Line Shapefile, 2016, Series Information for the Area Landmark State-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  14. TIGER/Line Shapefile, 2010, 2010 state, Hawaii, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  15. TIGER/Line Shapefile, 2010, 2010 Census Block State-based

    Data.gov (United States)

    U.S. Environmental Protection Agency — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  16. TIGER/Line Shapefile, 2010, 2010 state, Indiana, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  17. A line-based vegetation sampling technique and its application in ...

    African Journals Online (AJOL)

    percentage cover, density and intercept frequency) and also provides plant size distributions, yet requires no more sampling effort than the line-intercept method.. A field test of the three techniques in succulent karoo, showed that the discriminating ...

  18. Demographic Data - TIGER/Line Shapefile, 2010, 2010 state, Florida, 2010 Census Place State-based

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  19. TIGER/Line Shapefile, 2016, Series Information for the Current Census Tract State-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  20. TIGER/Line Shapefile, 2016, Series Information for the All Roads County-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  1. TIGER/Line Shapefile, 2010, 2010 state, Georgia, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  2. TIGER/Line Shapefile, 2013, Series Information File for the All Roads County-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  3. TIGER/Line Shapefile, 2010, 2010 state, California, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  4. TIGER/Line Shapefile, 2013, Series Information File for the Current Place State-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  5. TIGER/Line Shapefile, 2010, 2010 state, New York, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  6. TIGER/Line Shapefile, 2010, 2010 state, Virginia, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  7. Series Information File for the 2017 TIGER/Line Shapefile, All Roads County-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  8. TIGER/Line Shapefile, 2010, 2010 state, Texas, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  9. TIGER/Line Shapefile, 2010, 2010 state, Tennessee, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  10. TIGER/Line Shapefile, 2016, Series Information for the Current County Subdivision State-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  11. TIGER/Line Shapefile, 2016, Series Information for the Current Block Group State-based Shapefile

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  12. Power Line Interference Removal from Electrocardiogram Using a Simplified Lattice Based Adaptive IIR Notch Filter

    National Research Council Canada - National Science Library

    Dhillon, Santpal

    2001-01-01

    ...) notch filter with a simplified adaptation algorithm for removal of power line frequency from ECG signals, The performance of this filter is better as compared to a second order infinite impulse response (IIR...

  13. TIGER/Line Shapefile, 2010, 2010 state, Michigan, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  14. TIGER/Line Shapefile, 2017, state, Alaska, Current Alaska Native Regional Corporation (ANRC) State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  15. Constrained Convolutional Sparse Coding for Parametric Based Reconstruction of Line Drawings

    KAUST Repository

    Shaheen, Sara

    2017-12-25

    Convolutional sparse coding (CSC) plays an essential role in many computer vision applications ranging from image compression to deep learning. In this work, we spot the light on a new application where CSC can effectively serve, namely line drawing analysis. The process of drawing a line drawing can be approximated as the sparse spatial localization of a number of typical basic strokes, which in turn can be cast as a non-standard CSC model that considers the line drawing formation process from parametric curves. These curves are learned to optimize the fit between the model and a specific set of line drawings. Parametric representation of sketches is vital in enabling automatic sketch analysis, synthesis and manipulation. A couple of sketch manipulation examples are demonstrated in this work. Consequently, our novel method is expected to provide a reliable and automatic method for parametric sketch description. Through experiments, we empirically validate the convergence of our method to a feasible solution.

  16. TIGER/Line Shapefile, 2010, 2010 state, Delaware, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  17. TIGER/Line Shapefile, 2010, 2010 state, Idaho, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  18. TIGER/Line Shapefile, 2010, 2010 state, Montana, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  19. TIGER/Line Shapefile, 2010, 2010 state, Oregon, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  20. TIGER/Line Shapefile, 2010, 2010 state, Kansas, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  1. TIGER/Line Shapefile, 2010, 2010 state, Ohio, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  2. TIGER/Line Shapefile, 2010, 2010 state, South Dakota, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  3. TIGER/Line Shapefile, 2010, 2010 state, West Virginia, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  4. TIGER/Line Shapefile, 2010, 2010 state, Rhode Island, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  5. TIGER/Line Shapefile, 2010, 2010 state, Mississippi, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  6. TIGER/Line Shapefile, 2010, 2010 state, Colorado, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  7. TIGER/Line Shapefile, 2010, 2010 state, Kentucky, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  8. TIGER/Line Shapefile, 2010, 2010 state, Washington, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  9. TIGER/Line Shapefile, 2010, 2010 state, North Carolina, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  10. TIGER/Line Shapefile, 2010, 2010 state, North Dakota, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  11. TIGER/Line Shapefile, 2010, 2010 state, Maryland, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  12. TIGER/Line Shapefile, 2010, 2010 state, District of Columbia, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  13. TIGER/Line Shapefile, 2010, 2010 state, Wisconsin, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  14. TIGER/Line Shapefile, 2010, 2010 state, Missouri, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  15. TIGER/Line Shapefile, 2010, 2010 state, Illinois, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  16. TIGER/Line Shapefile, 2010, 2010 state, Alabama, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  17. TIGER/Line Shapefile, 2010, 2010 state, New Hampshire, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  18. TIGER/Line Shapefile, 2010, 2010 state, South Carolina, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  19. TIGER/Line Shapefile, 2010, 2010 state, Minnesota, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  20. TIGER/Line Shapefile, 2010, 2010 state, Connecticut, 2010 Census Block State-based

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...