Local socioeconomic changes and public fiscal implications of coal development in Wayne County, West Virginia

Energy Technology Data Exchange (ETDEWEB)

Metzger, J. E.; Mosena, P. W.; Stenehjem, E. J.

1978-09-01

This report attempts to characterize the economic and societal effects likely to accompany increased coal mining in and around Wayne County, West Virginia. The study concludes that population growth and increased demands for public services, with the exceptions of requirements for new roads, water, and sewer services, will be minimal as a result of the two new 2-million-tons-per-year deep mines planned for the area. The study estimates that both the County and the school district will experience positive new fiscal balances; i.e., more incremental annual revenue than additional mine-related annual expenditures. However, the town of Wayne is expected to experience a negative fiscal balance throughout the period of mine production. The study and its findings are each unique in several ways. First, the findings are somewhat unique in that major impacts (rapid population in-migration, shortages in housing and public services, and fiscal imbalances) are not projected to occur. In the heart of the coal mining district of Southern West Virginia similar levels of new mining may well have much different results. In areas, for example, where there are greater shortages of developable land, less adequate public and private infrastructure, and/or fewer available trained workers, the coal-related impacts would be dramatically different than those found for Wayne County. A second unique feature of this study concerns the manner in which it was originated and conducted. This study presents estimates of impacts for Wayne County and its associated jurisdictions which represent the combined knowledge and expertise of all parties involved: the citizens ofWayne County, the County Commission, the Advisory Board, the representatives from the Governor's Office, and the Argonne staff.

Radiological survey results at 914 Black Oak Ridge Road, Wayne, New Jersey (WJ005)

International Nuclear Information System (INIS)

Rodriguez, R.E.; Johnson, C.A.

1995-05-01

The US Department of Energy (DOE) conducted remedial action during 1993 at several vicinity properties in the Wayne and Pequannock Townships in New Jersey as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP). These properties are in the vicinity of the DOE-owned Wayne Interim Storage Site (WISS), formerly the W.R. Grace facility. The property at 914 Black Oak Ridge Road, Wayne, New Jersey was not one of these vicinity properties; however the owner requested that his property be radiologically surveyed. At the request of DOE, a team from Oak Ridge National Laboratory conducted a radiological scoping survey of this property. The purpose of the survey, conducted in early November 1993, was to determine whether any radiological contamination might be present on the property. The radiological survey included surface gamma scans and gamma readings at one meter, and the collection of soil and/or debris samples for radionuclide analysis. Results of the survey demonstrated no radionuclide concentrations or radiation measurements in excess of applicable DOE guidelines

Wayne Interim Storage Site: Annual environmental report for calendar year 1990, Wayne, New Jersey

International Nuclear Information System (INIS)

1991-09-01

Environmental monitoring of the US Department of Energy's (DOE) Wayne Interim Storage Site (WISS) (a National Priorities List site) and surrounding area began in 1984. WISS is part of the Formerly Utilized Sites Remedial Action Program (FUSRAP), a DOE program to decontaminate or otherwise control sites where residual radioactive materials remain from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. The environmental monitoring program at WISS includes sampling networks for radon and thoron concentrations in air; external gamma radiation exposure; and radium-226, thorium-232, and total uranium concentrations in surface water, sediment, and groundwater. Sediment samples were also analyzed for thorium-230, and several nonradiological parameters were measured in groundwater. 16 refs., 12 figs., 23 tabs

Diversity in Cyborg Images: A Case Study of Barry Levinson's "Toys."

Science.gov (United States)

Lucek, Linda E.

Associated with the cultural paradigm of postmodernism, the cyborg, in its numerous aspects, has become a predominant metaphor used to describe the relationship between humanity and technology in post-industrial information societies. This case study of Barry Levinson's 1992 comedy film, "Toys," demonstrates some of the many facets of…

Where History, Philosophy, and Psychology Meet: An Interview with Wayne Viney

Science.gov (United States)

Rutherford, Alexandra

2004-01-01

Wayne Viney is Professor of Psychology and University Distinguished Teaching Scholar at Colorado State University where he teaches graduate and undergraduate courses in the history of psychology. He is also inaugurating a new course, The Development of Scientific Thought, for the College of Natural Sciences at Colorado State. Earlier in his…

Flood-inundation maps for the St. Marys River at Fort Wayne, Indiana

Science.gov (United States)

Menke, Chad D.; Kim, Moon H.; Fowler, Kathleen K.

2012-01-01

Digital flood-inundation maps for a 9-mile reach of the St. Marys River that extends from South Anthony Boulevard to Main Street at Fort Wayne, Indiana, were created by the U.S. Geological Survey (USGS) in cooperation with the City of Fort Wayne. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site, depict estimates of the areal extent of flooding corresponding to selected water levels (stages) at the USGS streamgage 04182000 St. Marys River near Fort Wayne, Ind. Current conditions at the USGS streamgages in Indiana may be obtained from the National Water Information System: Web Interface. In addition, the information has been provided to the National Weather Service (NWS) for incorporation into their Advanced Hydrologic Prediction Service (AHPS) flood warning system. The NWS forecasts flood hydrographs at many places that are often collocated at USGS streamgages. That forecasted peak-stage information, also available on the Internet, may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, water-surface profiles were simulated for the stream reach by means of a hydraulic one-dimensional step-backwater model. The model was calibrated using the most current stage-discharge relation at the USGS streamgage 04182000 St. Marys River near Fort Wayne, Ind. The hydraulic model was then used to simulate 11 water-surface profiles for flood stages at 1-ft intervals referenced to the streamgage datum and ranging from bankfull to approximately the highest recorded water level at the streamgage. The simulated water-surface profiles were then combined with a geographic information system digital elevation model (derived from Light Detection and Ranging (LiDAR) data) in order to delineate the area flooded at each water level. A flood inundation map was generated for each water-surface profile stage (11 maps in all) so that for any given flood stage users will be

Broadening History, Expanding Possibilities: Contributions of Wayne Ramirez to Art Therapy

Science.gov (United States)

Potash, Jordan S.; Ramirez, Wayne A.

2013-01-01

A broad history of art therapy in the United States offers important perspectives on which to view contemporary art therapy practice and professional identity. This article provides descriptive research on the contributions of art therapist Wayne Ramirez, an active leader in the early days of the American Art Therapy Association whose attention…

Radioactive releases from a thorium-contaminated site in Wayne, New Jersey

International Nuclear Information System (INIS)

Wang, J.; Yang, J.; Merry-Libby, P.

1985-01-01

Various residues and wastes from the production of thorium and rare earths from monazite ore are buried on a hillside in Wayne, New Jersey. In addition, contaminated materials (primarily soils) from nearby vicinity properties are being consolidated onto the Wayne site. The US Department of Energy plans to stabilize all the contaminated materials on an interim basis (20 years) until funding is available to remove them to another location. In order to evaluate the effectiveness of interim stabilization measures, pre-remedial action radioactive releases are compared to estimated releases under a reference stabilization option (one meter of soil cover). Two potential pathways are examined: (1) airborne radioactive gases (thoron and radon) and particulates, and (2) seepage into the near-surface groundwater. The relative reduction of releases into the air and groundwater for the reference stabilization option is analyzed using mathematical models for radioactive gas fluxes and atmospheric dispersion as well as groundwater transport and dispersion. The consequent health implications for nearby individuals and the general population are also estimated. Health effects due to radioactive releases are estimated to be insignificant

Geophysical survey at Tell Barri (Syria)

Science.gov (United States)

Florio, Giovanni; Cella, Federico; Pierobon, Raffaella; Castaldo, Raffaele; Castiello, Gabriella; Fedi, Maurizio

2010-05-01

A geophysical survey at the archaeological site of Tell Barri (Northeasterm Syria) was carried out. The Tell (Arab word for "hill") is 32 m high with a whole covered area of 37 hectares. The Tell, with its huge dimensions and with a great amount of pottery on the surface, is a precious area to study the regional history from IV mill. BC to Islamic and Medieval period. The geophysical study consisted in magnetic and electromagnetic measurements in the lower town area. The aim of this survey was to provide evidence of the presence of buried archaeological structures around an already excavated area. The wall structures in the Tell Barri are made by backed or crude clay bricks. The instrument used for the magnetic survey was an Overhauser-effect proton magnetometer (Gem GSM-19GF), in gradiometric configuration. The electromagnetic instrument used, Geonics Ltd. EM31, implements a Frequency Domain Electromagnetic Method (FDEM). It was used in vertical coils configuration, and this choice should grant a maximum theoretical investigation depth of about 6 m. Before starting the measurements on a larger scale, we conducted a magnetic and EM test profile on some already excavated, outcropping, baked bricks walls. Results were encouraging, because clear and strong magnetic and EM anomalies were recorded over the outcropping walls. However, in the survey area these structures are covered by 3 to 4 meters of clay material and the increased sensors-structures distance will reduce the anomalies amplitude. Moreover, the cover material is disseminated with bricks, basalt blocks and ceramics, all of which have relevant magnetic properties. After magnetic surveying some 50 m side square areas, we verified that unfortunately their effect resulted to be dominant with respect to the deeper wall structures, degrading too much the signal-to-noise ratio. The processing and analysis of magnetic data is however currently underway and will determine decisions about further use of this method

Wayne Interim Storage Site annual environmental report for calendar year 1991, Wayne, New Jersey

International Nuclear Information System (INIS)

1992-09-01

This document describes the envirormental monitoring program at the Wayne Interim Storage Site (WISS) and surrounding area, implementation of the program, and monitoring results for 1991. Environmental monitoring of WISS and surrounding area began in 1984 when Congress added the site to the US Department of Energy's (DOE) Formerly Utilized Sites Remedial Action Program (FUSRAP). FUSRAP is a DOE program to decontaminate or otherwise control sites where residual radioactive materials remain from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. WISS is a National Priorities List site. The environmental monitoring program at WISS includes sampling networks for radon and thoron concentrations in air; external gamma radiation exposure; and radium-226, radium-228, thorium-232, and total uranium concentrations in surface water, sediment, and groundwater. Several nonradiological parameters are also measured in groundwater. Monitoring results are compared with applicable Environmental Protection Agency standards, DOE derived concentration guides, dose limits, and other requirements in DOE orders. Environmental standards are established to protect public health and the environment

Professor Barry Fraser's contributions to science education research

Science.gov (United States)

Aldridge, Jill M.

2011-09-01

In this article, I endeavour to convey the depth of Barry Fraser's contributions to science education research, including his tireless endeavours to promote and advance research, especially the field of learning environments, the realisation of his vision to create one of the largest doctoral programs in science and mathematics education in the world, his leadership capacity in terms of guiding and leading an internationally renowned centre and large-scale cross-national and cross-cultural studies, his dedication towards human capacity building in Africa, Asia and elsewhere, his capacity as a mentor and editor that have seen the publication of numerous journal articles and books and the ongoing success of science education research journals.

Researching Race and Social Justice in Education: Essays in Honour of Barry Troyna.

Science.gov (United States)

Sikes, Pat, Ed.; Rizvi, Fazal, Ed.

The essays in this book comprise a "festschrift", a group of essays, to commemorate Barry Troyna, who made an important contribution to thinking about race, racism, and research on social-justice issues in the school context. Much of his work was directed at showing that it was impossible to research questions of "race"…

Radiological verification survey results at 898 Black Oak Ridge Rd., Wayne, New Jersey (WJ004V)

International Nuclear Information System (INIS)

Rodriguez, R.E.; Johnson, C.A.

1995-05-01

The US Department of Energy (DOE) conducted remedial action during 1993 at the Pompton Plains Railroad Spur and eight vicinity properties in the Wayne and Pequannock Townships in New Jersey as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP). These properties are in the vicinity of the DOE-owned Wayne Interim Storage Site (WISS), formerly the W.R. Grace facility. The property at 898 Black Oak Ridge Road, Wayne, New Jersey is one of these vicinity properties. At the request of DOE, a team from Oak Ridge National Laboratory conducted an independent radiological verification survey at this property. The purpose of the survey, conducted between September and December 1993, was to confirm the success of the remedial actions performed to remove any radioactive materials in excess of the identified guidelines. The verification survey included surface gamma scans and gamma readings at one meter, beta-gamma scans, and the collection of soil and debris samples for radionuclide analysis. Results of the survey demonstrated that all radiological measurements on the property at 898 Black Oak Ridge Road were within applicable DOE guidelines. Based on the results of the remedial action data and confirmed by the verification survey data, the portions of the site that had been remediated during this action successfully meet the DOE remedial action objectives

Barry shunt for treatment of a 76-hour stuttering priapism without subsequent erectile dysfunction

Directory of Open Access Journals (Sweden)

Osmonov DK

2014-07-01

Full Text Available Daniar Kurmanbekovich Osmonov, Aleksey Aksenov, Andrea Nathaly Guerra Sandoval, Almut Kalz, Klaus Peter Juenemann Department of Urology and Pediatric Urology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany Introduction: This paper reports treatment of a 76-hour low-flow priapism with a shunting procedure that was first described by Barry in 1976. We were able to observe the preservation of erectile function despite the long period of ischemia. A review of the literature shows that there are few reports of erectile function recovery after a priapism of similar duration. Materials and methods: A 42-year-old patient presented with a 76-hour priapism, probably caused by consumption of alcohol and illegal drugs. A Barry Shunt procedure was performed. The erectile function of the patient was assessed by means of International Index of Erectile Function score over a follow-up period of 30 months. Moreover, we reviewed different surgical options for treatment of priapism in the literature. Results: Partial return of erection without sexual arousal occurred on two occasions during the 10-day hospitalization, but was treated by manipulation of the penis, ie, by milking the tumescence into the shunt. After 3 months, the shunt was still palpable as a subcutaneous swelling. Six months postoperatively, the residual swelling had disappeared. The International Index of Erectile Function score was of 21 without phosphodiesterase type 5 inhibitors after a follow-up of 2.5 years. Conclusion: Barry shunt is an effective alternative surgical option for the treatment of low-flow priapism. In the case of our patient, it was also effective after a 76-hour-lasting priapism. Keywords: low flow priapism, erectile function, cavernovenous shunt, surgical treatment of stuttering priapism

OIL WELL REMEDIATION IN CLAY AND WAYNE COUNTIES, IL

Energy Technology Data Exchange (ETDEWEB)

Peter L. Dakuras; Larry Stieber; Dick Young

2003-07-09

This is the second progress and final technical report of the remediation of abandoned wells in Clay and Wayne Counties in Illinois. The wells will be identified as the Routt No.3 and No.4 and the Bates Hosselton 1 and 2. Both sites have met all legal, financial and environmental requirements to drill and/or pump oil on both leases. We have also obtained all available information about both leases. All steps were taken to improve access roads, dig the necessary pits, and build the necessary firewalls. This progress and final technical report will address the remediation efforts as well as our results and conclusions.

Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.

Science.gov (United States)

Rainsford, K D; Haynes, D R

2013-08-01

This issue of Inflammopharmacology contains papers that have been submitted to commemorate the life and work of Professor Barrie Vernon-Roberts, an outstanding clinical scientist in the field of bone pathology and its pharmacological regulation. This review briefly summarizes his major works and achievements as well as a list of his publications.

75 FR 39460 - Prevailing Rate Systems; Redefinition of the Chicago, IL; Fort Wayne-Marion, IN; Indianapolis, IN...

Science.gov (United States)

2010-07-09

...-AM21 Prevailing Rate Systems; Redefinition of the Chicago, IL; Fort Wayne-Marion, IN; Indianapolis, IN... wage area. These changes are based on recent consensus recommendations of the Federal Prevailing Rate... below. The Federal Prevailing Rate Advisory Committee (FPRAC), the national labor-management committee...

The Art of Being Persuaded: Wayne Booth's Mutual Inquiry and the Trust to Listen

Science.gov (United States)

Baker, Marsha Lee; Dieter, Eric; Dobbins, Zachary

2014-01-01

This article examines Wayne C. Booth's legacy as a teacher and scholar through the concept of rhetoric as mutual inquiry that he develops from "Modern Dogma and the Rhetoric of Assent" (1974) through "The Rhetoric of Rhetoric" (2004). Booth's work connects the political and pedagogical in pragmatic and productive ways…

Baseline assessment of groundwater quality in Wayne County, Pennsylvania, 2014

Science.gov (United States)

Senior, Lisa A.; Cravotta, III, Charles A.; Sloto, Ronald A.

2016-06-30

The Devonian-age Marcellus Shale and the Ordovician-age Utica Shale, geologic formations which have potential for natural gas development, underlie Wayne County and neighboring counties in northeastern Pennsylvania. In 2014, the U.S. Geological Survey, in cooperation with the Wayne Conservation District, conducted a study to assess baseline shallow groundwater quality in bedrock aquifers in Wayne County prior to potential extensive shale-gas development. The 2014 study expanded on previous, more limited studies that included sampling of groundwater from 2 wells in 2011 and 32 wells in 2013 in Wayne County. Eighty-nine water wells were sampled in summer 2014 to provide data on the presence of methane and other aspects of existing groundwater quality throughout the county, including concentrations of inorganic constituents commonly present at low levels in shallow, fresh groundwater but elevated in brines associated with fluids extracted from geologic formations during shale-gas development. Depths of sampled wells ranged from 85 to 1,300 feet (ft) with a median of 291 ft. All of the groundwater samples collected in 2014 were analyzed for bacteria, major ions, nutrients, selected inorganic trace constituents (including metals and other elements), radon-222, gross alpha- and gross beta-particle activity, selected man-made organic compounds (including volatile organic compounds and glycols), dissolved gases (methane, ethane, and propane), and, if sufficient methane was present, the isotopic composition of methane.Results of the 2014 study show that groundwater quality generally met most drinking-water standards, but some well-water samples had one or more constituents or properties, including arsenic, iron, pH, bacteria, and radon-222, that exceeded primary or secondary maximum contaminant levels (MCLs). Arsenic concentrations were higher than the MCL of 10 micrograms per liter (µg/L) in 4 of 89 samples (4.5 percent) with concentrations as high as 20 µg/L; arsenic

La clientèle de l’architecte Barry Dierks sur la Côte d’Azur

Directory of Open Access Journals (Sweden)

François Fray

2012-05-01

Full Text Available Architecte américain formé au Carnegie Institute of Technology de Pittsburgh, Barry Dierks (1899-1960 a passé toute sa carrière sur la Côte d’Azur à partir de 1925. Il y construisit la maison qui devait être sa résidence, son agence et sa vitrine. Il a su, avec son ami anglais Eric Sawyer, capter l’intérêt d’une clientèle internationale, exigeante, cultivée et informée, venue chercher sur cette côte à la fois le dépaysement et des résonances à sa propre culture, mais pas forcément des réalisations d’avant-garde. Barry Dierks a su y répondre et se muer en architecte à la fois moderne et méditerranéen en se coulant sans se renier dans les desiderata de ses clients. La Seconde Guerre mondiale a interrompu ses activités. Mais ses actions humanitaires et leur engagement pendant cette période leur valut à tous deux respect et reconnaissance. Une centaine de chantiers ont pu être identifiés, grandes et petites maisons, pavillons de bain et même un bowling privé.

Wayne Interim Storage Site environmental report for calendar year 1992, 868 Black Oak Ridge Road, Wayne, New Jersey

International Nuclear Information System (INIS)

1993-05-01

This report describes the environmental surveillance program at the Wayne Interim Storage Site (WISS) and provides the results for 1992. The fenced, site, 32 km (20 mi) northwest of Newark, New Jersey, was used between 1948 and 1971 for commercial processing of monazite sand to separate natural radioisotopes - predominantly thorium. Environmental surveillance of WISS began in 1984 in accordance with Department of Energy (DOE) Order 5400.1 when Congress added the site to DOE's Formerly Utilized Sites Remedial Action Program (FUSRAP). The environmental surveillance program at WISS includes sampling networks for radon and thoron in air; external gamma radiation exposure; radium-226, radium-228, thorium-230, thorium-232, total uranium, and several chemicals in surface water and sediment; and total uranium, radium-226, radium-228, thorium-230, thorium-232, and organic and inorganic chemicals in groundwater. Monitoring results are compared with applicable Environmental Protection Agency (EPA) and state standards, DOE derived concentration guides (DCGs), dose limits, and other DOE requirements. This monitoring program assists in fulfilling the DOE policy of measuring and monitoring effluents from DOE activities and calculating hypothetical doses. Results for environmental surveillance in 1992 show that the concentrations of all radioactive and most chemical contaminants were below applicable standards

Brian Barry: innovative contributions to transdermal and topical drug delivery.

Science.gov (United States)

Williams, A C

2013-01-01

Brian Barry published over 300 research articles across topics ranging from colloid science, vasoconstriction and the importance of thermodynamics in dermal drug delivery to exploring the structure and organisation of the stratum corneum barrier lipids and numerous strategies for improving topical and transdermal drug delivery, including penetration enhancers, supersaturation, coacervation, eutectic formation and the use of varied liposomes. As research in the area blossomed in the early 1980s, Brian wrote the book that became essential reading for both new and established dermal delivery scientists, explaining the background mathematics and principles through to formulation design. Brian also worked with numerous scientists, as collaborators and students, who have themselves taken his rigorous approach to scientific investigation into their own research groups. This paper can only describe a small fraction of the many significant contributions that Brian made to the field during his 40-year academic career.

Results of the independent radiological verification survey of the lower Sheffield Brook floodplain, Wayne, New Jersey

International Nuclear Information System (INIS)

Yalcintas, M.G.; Carrier, R.F.

1989-05-01

Prior to 1971, the W.R. Grace Company processed and stored radioactive materials at Wayne, New Jersey, under license to the Atomic Energy Commission. Decontamination of structures and storage of waste materials on the property at the Wayne Interim Storage Site (WISS) took place in 1974. Surveys by the State of New Jersey Department of Environmental Protection and by Oak Ridge Associated Universities for the NRC in 1982 indicated that properties adjacent to the WISS contained surface contamination by radioactive residuals in amounts exceeding those acceptable under US Department of Energy (DOE) remedial action guidelines. At the request of DOE, remedial actions have been conducted by Bechtel National, Inc., to remove radioactive residuals from properties adjacent to the site. It is the policy of DOE to assign an independent verification contractor to ensure the effectiveness of remedial actions performed within the Formerly Utilized Sites Remedial Action Program. This report describes the methods and results of those studies that were conducted by the Measurement Applications and Development Group of the Oak Ridge National Laboratory for the lower Sheffield Brook floodplain west of the WISS. Based upon post-remedial action and verification survey data, it was concluded that residual soil concentrations and gamma levels following excavation and backfilling of the area are within the limits prescribed by DOE radiological guidelines. 12 refs., 6 figs., 8 tabs

Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS

Science.gov (United States)

Borrás-Linares, Isabel; Herranz-López, María; Barrajón-Catalán, Enrique; Arráez-Román, David; González-Álvarez, Isabel; Bermejo, Marival; Gutiérrez, Alberto Fernández; Micol, Vicente; Segura-Carretero, Antonio

2015-01-01

Previous findings on the capacity of Hibiscus sabdariffa (HS) polyphenols to ameliorate metabolic disturbances justify the necessity of studies oriented to find the potential metabolites responsible for such an effect. The present study examined the intestinal epithelial membrane permeability of polyphenols present in a phenolic-enriched Hibiscus sabdariffa extract (PEHS), free and encapsulated, using the Caco-2 cell line. Additionally, selected polyphenols (quercetin, quercetin-3-glucoside, quercetin-3-glucuronide, and N-feruloyltyramine) were also studied in the same absorption model. The powerful analytical platform used ultra-high-performance liquid chromatography coupled with ultra-high-resolution quadrupole time-of-flight mass spectrometry (UHPLC-ESI-UHR-Qq-TOF-MS), and enabled the characterization of seven new compounds in PEHS. In the permeation study, only a few compounds were able to cross the cell monolayer and the permeability was lower when the extract was in an encapsulated form. Pure compounds showed a moderate absorption in all cases. Nevertheless, these preliminary results may need further research to understand the complete absorption mechanism of Hibiscus polyphenols. PMID:26262611

Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS

Directory of Open Access Journals (Sweden)

Isabel Borrás-Linares

2015-08-01

Full Text Available Previous findings on the capacity of Hibiscus sabdariffa (HS polyphenols to ameliorate metabolic disturbances justify the necessity of studies oriented to find the potential metabolites responsible for such an effect. The present study examined the intestinal epithelial membrane permeability of polyphenols present in a phenolic-enriched Hibiscus sabdariffa extract (PEHS, free and encapsulated, using the Caco-2 cell line. Additionally, selected polyphenols (quercetin, quercetin-3-glucoside, quercetin-3-glucuronide, and N-feruloyltyramine were also studied in the same absorption model. The powerful analytical platform used ultra-high-performance liquid chromatography coupled with ultra-high-resolution quadrupole time-of-flight mass spectrometry (UHPLC-ESI-UHR-Qq-TOF-MS, and enabled the characterization of seven new compounds in PEHS. In the permeation study, only a few compounds were able to cross the cell monolayer and the permeability was lower when the extract was in an encapsulated form. Pure compounds showed a moderate absorption in all cases. Nevertheless, these preliminary results may need further research to understand the complete absorption mechanism of Hibiscus polyphenols.

Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS.

Science.gov (United States)

Borrás-Linares, Isabel; Herranz-López, María; Barrajón-Catalán, Enrique; Arráez-Román, David; González-Álvarez, Isabel; Bermejo, Marival; Fernández Gutiérrez, Alberto; Micol, Vicente; Segura-Carretero, Antonio

2015-08-07

Previous findings on the capacity of Hibiscus sabdariffa (HS) polyphenols to ameliorate metabolic disturbances justify the necessity of studies oriented to find the potential metabolites responsible for such an effect. The present study examined the intestinal epithelial membrane permeability of polyphenols present in a phenolic-enriched Hibiscus sabdariffa extract (PEHS), free and encapsulated, using the Caco-2 cell line. Additionally, selected polyphenols (quercetin, quercetin-3-glucoside, quercetin-3-glucuronide, and N-feruloyltyramine) were also studied in the same absorption model. The powerful analytical platform used ultra-high-performance liquid chromatography coupled with ultra-high-resolution quadrupole time-of-flight mass spectrometry (UHPLC-ESI-UHR-Qq-TOF-MS), and enabled the characterization of seven new compounds in PEHS. In the permeation study, only a few compounds were able to cross the cell monolayer and the permeability was lower when the extract was in an encapsulated form. Pure compounds showed a moderate absorption in all cases. Nevertheless, these preliminary results may need further research to understand the complete absorption mechanism of Hibiscus polyphenols.

Smoke (Paul Auster et Wayne Wang, 1995 : une œuvre à la croisée des arts

Directory of Open Access Journals (Sweden)

Delphine Letort

2011-04-01

Full Text Available The adaptation of the short story entitled “Auggie Wren’s Christmas Story” (1990 gathered the writer Paul Auster and the director Wayne Wang around a film project that allowed them to share their artistic practices in a collaborative work. This paper examines the question that underpins the narrative of the short-story by grappling with the appropriations of the real in other artistic modes. Paul Auster’s first encounter with the cinema points out the convergence between aural writing and cinematic writing, evoked through the double figure of the writer and that of the tale-teller/photographer in both the film and the short story.L’adaptation de la nouvelle « Auggie Wren’s Christmas Story » (1990 réunit l’écrivain Paul Auster et le réalisateur Wayne Wang autour d’un projet qui leur permit de croiser leurs pratiques artistiques dans un travail de collaboration. Cet article prolonge le questionnement artistique qui sous-tend le récit de la nouvelle en interrogeant les modalités de l’appropriation du réel par d’autres arts. La première rencontre entre Paul Auster et le cinéma met en relief les points de convergence entre écriture verbale et écriture cinématographique, évoqués autour de la double figure de l’écrivain et du conteur/photographe dans le film et dans la nouvelle.

Wayne Interim Storage Site environmental report for calendar year 1992, 868 Black Oak Ridge Road, Wayne, New Jersey. Formerly Utilized Sites Remedial Action Program (FUSRAP)

Energy Technology Data Exchange (ETDEWEB)

1993-05-01

This report describes the environmental surveillance program at the Wayne Interim Storage Site (WISS) and provides the results for 1992. The fenced, site, 32 km (20 mi) northwest of Newark, New Jersey, was used between 1948 and 1971 for commercial processing of monazite sand to separate natural radioisotopes - predominantly thorium. Environmental surveillance of WISS began in 1984 in accordance with Department of Energy (DOE) Order 5400.1 when Congress added the site to DOE`s Formerly Utilized Sites Remedial Action Program (FUSRAP). The environmental surveillance program at WISS includes sampling networks for radon and thoron in air; external gamma radiation exposure; radium-226, radium-228, thorium-230, thorium-232, total uranium, and several chemicals in surface water and sediment; and total uranium, radium-226, radium-228, thorium-230, thorium-232, and organic and inorganic chemicals in groundwater. Monitoring results are compared with applicable Environmental Protection Agency (EPA) and state standards, DOE derived concentration guides (DCGs), dose limits, and other DOE requirements. This monitoring program assists in fulfilling the DOE policy of measuring and monitoring effluents from DOE activities and calculating hypothetical doses. Results for environmental surveillance in 1992 show that the concentrations of all radioactive and most chemical contaminants were below applicable standards.

Operational Implementation of the MARSSIM Process at the Wayne Interim Storage Site

International Nuclear Information System (INIS)

Hays, D. C. Jr.; Trujillo, P. A. IV.; Zoller, S. G.

2002-01-01

This paper describes the methodologies behind the operational implementation of the Multi Agency Radiation Site Survey and Investigation Manual (MARSSIM) process at the Wayne Interim Storage Site (WISS). The United States Army Corps of Engineers (USACE) and Environmental Chemical Corporation (ECC) have implemented the MARSSIM process using various surveys producing raw data. The final remedial status of a survey unit is derived through data reduction, while maintaining a high degree of efficiency in the construction aspects of the remedial action. Data reduction of field measurements is accomplished by merging the data outputs of a Digital Global Positioning System, an exposure rate meter, and laboratory analyses to produce maps which present exposure rates, elevations, survey unit boundaries, direct measurement locations, and sampling locations on a single map. The map serves as a data-posting plot and allows the project team to easily judge the survey unit's remedial status. The operational implementation of the MARSSIM process has been successful in determining the eligibility of survey units for final status surveys at the WISS and also in demonstrating final status radiological and chemical conditions while maintaining an efficient remedial action effort

The relationship between cannabis use and cortisol levels in youth at ultra high-risk for psychosis.

Science.gov (United States)

Carol, Emily E; Spencer, Robert L; Mittal, Vijay A

2017-09-01

Recent studies have posited a relationship between cannabis use and the biological stress system, but this critical relationship has not been evaluated during the ultra high-risk (UHR) period immediately preceding the onset of psychotic disorders. Salivary cortisol samples were collected on 46 UHR and 29 control adolescents; these individuals were assessed for current cannabis use with a urine panel and self-report. UHR participants where separated into two groups: Current Cannabis Use (UHR-CU) and No Current Cannabis Use (UHR-NC). Healthy Control participants (HC) were free of cannabis use. Consistent with the literature, results indicate UHR individuals showed elevated cortisol levels when compared to HC participants. Further, we also observed that UHR-CU participants exhibited elevated levels when compared to both the non-using UHR and HC groups. Findings suggest that cannabis use may interact with underlying biological vulnerability associated with the hypothalamic-pituitary-adrenal (HPA) axis system. Published by Elsevier Ltd.

Start with an Hour a Week: Enhancing Usability at Wayne State University Libraries

Directory of Open Access Journals (Sweden)

Maria Nuccilli

2018-01-01

Full Text Available Instead of pursuing traditional testing methods, Discovery and Innovation at Wayne State University Libraries settled on an alternate path to user-centered design when redesigning our library website: running hour-long “guerrilla” usability tests each week for two semesters. The team found immediate successes with this simple, cost-effective method of usability testing, leading to similar redesign projects for other online resources. Emphasizing the importance of iterative design and continuous improvement, this article will detail the authors’ experience conducting short weekly tests, suggestions for institutions looking to begin similar testing programs, and low-stakes testing as a pathway to improved design for the library as a whole. In spring 2016, the Discovery and Innovation web team at Wayne State University Libraries began a redesign of our main library homepage, making the first major updates to the site since 2013. After launching the initial design, we wanted to improve the new website with feedback from real users, following Jakob Nielsen’s decades-old assertion that redesigning websites based on user feedback “can substantially improve usability” (Nielsen, 1993. Instead of using remote and large-scale testing options, we chose a lean, iterative approach, and committed to two semesters of brief, weekly “guerrilla” usability sessions with student users. Not only did this method produce powerful results, but its attainable, iterative approach ultimately led to an increased user focus beyond the library homepage. If you have an hour a week, a laptop, and at least one other colleague willing to help, you can start usability testing, guerrilla-style. Though we found success with this method, using such a stripped-down approach wasn’t immediately obvious. At the beginning of this project, we didn’t know a whole lot about conducting user testing, having relied mostly on survey responses, search logs, and Piwik website

WACANA SYARIAT KONTEMPORER DI BARAT: Studi Pemikiran Wael B. Hallaq dan M. Barry Hooker

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Mohamad Abdun Nasir

2017-07-01

Full Text Available Contemporary popular discourses about Islam, shari’a and Islamic law in the West is often filled with the issues of terrorism, anti-democracy, human rights violation and women’s minor status in Islam, which all lead into negative perception. Unlike such popular views, Western scholars perceive shari’a from various perspectives. They are quite critical to shari’a in a positive sense. This article discusses Western scholarly discourses on shari’a by comparing the thoughts and works of two most prominent figures, Wael B. Hallaq and M. Barry Hooker, who always concern with shari’a, Islamic law and related social issues, such modernity, colonialism and legal system. Based on the model of the study of public figure and grounded its main data on Hallaq’s and Hooker’s main work, this study shows that these two scholars promote idealistic and contextual perception on shari’a. From the ideal point of view, shari’a is seen a product of scholarly independent work by Muslim jurists, whose authority now is unfortunately taken over by the state. The contextual view regards shari’a as flexible Islamic religious or legal norms that are adaptable to the changing social and political environments so they are easily transferrable into the educational, legal and political system in a country like Indonesia, entailing what is called “national mazhab”.

Examining speed of processing of facial emotion recognition in individuals at ultra-high risk for psychosis

DEFF Research Database (Denmark)

Glenthøj, Louise Birkedal; Fagerlund, Birgitte; Bak, Nikolaj

2018-01-01

Emotion recognition is an aspect of social cognition that may be a key predictor of functioning and transition to psychosis in individuals at ultra-high risk (UHR) for psychosis ( Allott et al., 2014 ). UHR individuals exhibit deficits in accurately identifying facial emotions ( van Donkersgoed et...... al., 2015 ), but other potential anomalies in facial emotion recognition are largely unexplored. This study aimed to extend current knowledge on emotion recognition deficits in UHR individuals by examining: 1) whether UHR would display significantly slower facial emotion recognition than healthy...... controls, 2) whether an association between emotion recognition accuracy and emotion recognition latency is present in UHR, 3) the relationships between emotion recognition accuracy, neurocognition and psychopathology in UHR....

Niacin Skin Sensitivity Is Increased in Adolescents at Ultra-High Risk for Psychosis.

Directory of Open Access Journals (Sweden)

Gregor E Berger

Full Text Available Most studies provide evidence that the skin flush response to nicotinic acid (niacin stimulation is impaired in schizophrenia. However, only little is known about niacin sensitivity in the ultra-high risk (UHR phase of psychotic disorders.We compared visual ratings of niacin sensitivity between adolescents at UHR for psychosis according to the one year transition outcome (UHR-T n = 11; UHR-NT n = 55 with healthy controls (HC n = 25 and first episode schizophrenia patients (FEP n = 25 treated with atypical antipsychotics.Contrary to our hypothesis niacin sensitivity of the entire UHR group was not attenuated, but significantly increased compared to the HC group, whereas no difference could be found between the UHR-T and UHR-NT groups. As expected, niacin sensitivity of FEP was attenuated compared to HC group. In UHR individuals niacin sensitivity was inversely correlated with omega-6 and -9 fatty acids (FA, but positively correlated with phospholipase A2 (inPLA2 activity, a marker of membrane lipid repair/remodelling.Increased niacin sensitivity in UHR states likely indicates an impaired balance of eicosanoids and omega-6/-9 FA at a membrane level. Our findings suggest that the emergence of psychosis is associated with an increased mobilisation of eicosanoids prior to the transition to psychosis possibly reflecting a "pro-inflammatory state", whereas thereafter eicosanoid mobilisation seems to be attenuated. Potential treatment implications for the UHR state should be further investigated.

Stratigraphy and structure of the Miners Mountain area, Wayne County, Utah

Science.gov (United States)

Luedke, Robert G.

1953-01-01

The Miners Mountain area includes about 85 square miles in Wayne County, south-central Utah. The area is semiarid and characterized by cliffs and deep canyons. Formations range in age from Permian to Upper Jurassic and have an aggregate thickness of about 3,500 feet. Permian formations are the buff Coconino sandstone and the overlying white, limy, shert-containing Kaibab limestone. Unconformably overlying the Kaihab is the lower Triassic Moenkopi formation of reddish-brown and yellow mudstone, siltstone, and sandstone; it contains the Sinbad limestone member (?) in the lower part. Thin, lenticular Shinarump conglomerate unconformably overlies the Moenkopi, but grades upward into the Upper Triassic Chinle formation of variegated mudstone with some interbedded sandstone and limestone lenses. Uncomformably overlying the Chinle are the Wingate sandstone, Kayenta formation, and Navajo sandstone of the Jurassic (?) Glen Canyon group, which consist of red to white sandstone. Only the lower part of the Carmel formation of the Upper Jurassic San Rafael group is exposed in the area; it consists of variegated siltstone, sandstone, limestone, and gypsum. The conspicuous structural feature in the area is the Teasdale anticline which trends northwest, is about 14 miles long, and is asymmetric with a steeper west flank. Bounding the anticline on the northeast and east is the Capitol Reef monocline, the northern part of the Waterpocket Fold. Strata in the area are broken by steeply-dipping normal faults with small displacements, except for the Teasdale fault which has a maximum displacement of over 1,000 feet. Jointing is prominent in some formations. The major orogenic movement in the area is believed to be late Upper Cretaceous to early Tertiary. Epeirogenic uplift occurred intermittently throughout Tertiary and perhaps Quaternary time.

Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individuals.

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Fornito, Alex; Yung, Alison R; Wood, Stephen J; Phillips, Lisa J; Nelson, Barnaby; Cotton, Sue; Velakoulis, Dennis; McGorry, Patrick D; Pantelis, Christos; Yücel, Murat

2008-11-01

Abnormalities of the anterior cingulate cortex (ACC) are frequently implicated in the pathophysiology of psychotic disorders, but whether such changes are apparent before psychosis onset remains unclear. In this study, we characterized prepsychotic ACC abnormalities in a sample of individuals at ultra-high-risk (UHR) for psychosis. Participants underwent baseline magnetic resonance imaging and were followed-up over 12-24 months to ascertain diagnostic outcomes. Baseline ACC morphometry was then compared between UHR individuals who developed psychosis (UHR-P; n = 35), those who did not (UHR-NP; n = 35), and healthy control subjects (n = 33). Relative to control subjects, UHR-P individuals displayed bilateral thinning of a rostral paralimbic ACC region that was negatively correlated with negative symptoms, whereas UHR-NP individuals displayed a relative thickening of dorsal and rostral limbic areas that was correlated with anxiety ratings. Baseline ACC differences between the two UHR groups predicted time to psychosis onset, independently of symptomatology. Subdiagnostic comparisons revealed that changes in the UHR-P group were driven by individuals subsequently diagnosed with a schizophrenia spectrum psychosis. These findings indicate that anatomic abnormalities of the ACC precede psychosis onset and that baseline ACC differences distinguish between UHR individuals who do and do not subsequently develop frank psychosis. They also indicate that prepsychotic changes are relatively specific to individuals who develop a schizophrenia spectrum disorder, suggesting they may represent a diagnostically specific risk marker.

Use of DNA Markers for Investigating Sources of Bacteria in Contaminated Ground Water: Wooster Township, Wayne County, Ohio

Science.gov (United States)

Dumouchelle, Denise H.

2006-01-01

In 2004, a public-health nuisance was declared by the Wayne County Board of Health in the Scenic Heights Drive-Batdorf Road area of Wooster Township, Wayne County, Ohio, because of concerns about the safety of water from local wells. Repeated sampling had detected the presence of fecal-indicator bacteria and elevated nitrate concentrations. In June 2006, the U.S. Geological Survey (USGS), in cooperation with the Ohio Environmental Protection Agency (Ohio EPA), collected and analyzed samples from some of the affected wells to help investigate the possibility of human-origin bacterial contamination. Water samples from 12 wells and 5 home sewage-treatment systems (HSTS) were collected. Bromide concentrations were determined in samples from the 12 wells. Samples from 5 of the 12 wells were analyzed for wastewater compounds. Total coliform, enterococci and Escherichia coli (E. coli) bacteria concentrations were determined for samples from 8 of the 12 wells. In addition, two microbial source-tracking tools that employ DNA markers were used on samples from several wells and a composite sample of water from five septic tanks. The DNA markers from the Enterococcus faecium species and the order Bacteroidales are associated with specific sources, either human or ruminant sources. Bromide concentrations ranged from 0.04 to 0.18 milligrams per liter (mg/L). No wastewater compounds were detected at concentrations above the reporting limits. Samples from the 12 wells also were collected by Ohio EPA and analyzed for chloride and nitrate. Chloride concentrations ranged from 12.6 to 61.6 mg/L and nitrate concentrations ranged from 2.34 to 11.9 mg/L (as N). Total coliforms and enterococci were detected in samples from 8 wells, at concentrations from 2 to 200 colony-forming units per 100 milliliters (CFU/100 mL) and 0.5 to 17 CFU/100 mL, respectively. E. coli were detected in samples from three of the eight wells, at concentrations of 1 or 2 CFU/100 mL. Tests for the human

Patterns of white matter microstructure in individuals at ultra-high-risk for psychosis

DEFF Research Database (Denmark)

Krakauer, K; Ebdrup, B H; Glenthøj, B Y

2017-01-01

BACKGROUND: Individuals at ultra-high-risk (UHR) for psychosis present with emerging symptoms and decline in functioning. Previous univariate analyses have indicated widespread white matter (WM) aberrations in multiple brain regions in UHR individuals and patients with schizophrenia. Using multiv......, MO, and higher RD. CONCLUSIONS: UHR individuals demonstrate complex brain patterns of WM abnormalities. Despite the subtle psychopathology of UHR individuals, aberrations in WM appear associated with positive and negative symptoms as well as level of functioning....

Neurocognitive predictors of transition to psychosis: medium- to long-term findings from a sample at ultra-high risk for psychosis.

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Lin, A; Yung, A R; Nelson, B; Brewer, W J; Riley, R; Simmons, M; Pantelis, C; Wood, S J

2013-11-01

Individuals at ultra-high risk (UHR) for psychosis show reduced neurocognitive performance across domains but it is unclear which reductions are associated with transition to frank psychosis. The aim of this study was to investigate differences in baseline neurocognitive performance between UHR participants with (UHR-P) and without transition to psychosis (UHR-NP) and a healthy control (HC) group and examine neurocognitive predictors of transition over the medium to long term. A sample of 325 UHR participants recruited consecutively from the Personal Assessment and Crisis Evaluation (PACE) Clinic in Melbourne and 66 HCs completed a neurocognitive assessment at baseline. The UHR group was followed up between 2.39 and 14.86 (median = 6.45) years later. Cox regression was used to investigate candidate neurocognitive predictors of psychosis onset. The UHR group performed more poorly than the HC group across a range of neurocognitive domains but only performance on digit symbol coding and picture completion differed between the groups. The risk of transition was only significantly associated with poorer performance on visual reproduction [hazard ratio (HR) 0.919, 95% confidence interval (CI) 0.876-0.965, p = 0.001] and matrix reasoning (HR 0.938, 95% CI 0.883-0.996, p = 0.037). These remained significant even after controlling for psychopathology at baseline. This study is the longest follow-up of an UHR sample to date. UHR status was associated with poorer neurocognitive performance compared to HCs on some tasks. Cognition at identification as UHR was not a strong predictor of risk for transition to psychosis. The results suggests the need to include more experimental paradigms that isolate discrete cognitive processes to better understand neurocognition at this early stage of illness.

General intellectual functioning as a buffer against theory-of-mind deficits in individuals at ultra-high risk for psychosis.

Science.gov (United States)

Hur, Ji-Won; Byun, Min Soo; Shin, Na Young; Shin, Ye Seul; Kim, Sung Nyun; Jang, Joon Hwan; Kwon, Jun Soo

2013-09-01

The influence of neurocognition, including general intelligence, on theory of mind (ToM) among patients with schizophrenia spectrum disorder is controversial. The purpose of the present study was to identify the influences of the non-ToM cognition and general intelligence on ToM performance in individuals at ultra-high risk (UHR) for psychosis. Fifty-five UHR subjects and 58 healthy controls (HCs) completed neurocognitive, verbal, and nonverbal ToM tasks. UHR individuals showed poorer performance in the two verbal ToM tasks, the false-belief task and the strange-story tasks. Moreover, the UHR subjects displayed poorer recall on the interference list of the verbal learning test. Linear regression analysis revealed that neurocognitive functioning, including executive functioning, working memory, and general intelligence, accounted for significant amounts of the variance in the results for UHR individuals: 20.4% in the false-belief task, 44.0% in the strange-story task, and 49.0% in the nonverbal cartoon task. Neurocognition, including general intelligence, was not a significant contributor to performance on ToM tasks in HCs. ToM deficits were not noted in UHR individuals with above-average IQ scores (≥ 110) compared with UHR subjects with IQ scores less than 110, who displayed significant differences on all ToM tasks compared with HCs. The present results suggest that ToM deficits in UHR individuals are complex and may be influenced by non-ToM cognition. Our findings are discussed in relation to the role of neurocognitive abilities in ToM-related impairments in UHR individuals. Copyright © 2013 Elsevier B.V. All rights reserved.

Personality features in ultra-high risk for psychosis: a comparative study with schizophrenia and control subjects using the Temperament and Character Inventory-Revised (TCI-R).

Science.gov (United States)

Fresán, Ana; León-Ortiz, Pablo; Robles-García, Rebeca; Azcárraga, Mariana; Guizar, Diana; Reyes-Madrigal, Francisco; Tovilla-Zárate, Carlos Alfonso; de la Fuente-Sandoval, Camilo

2015-02-01

Several variables have been identified as risk factors for conversion to overt psychosis in ultra-high risk for psychosis (UHR) individuals. Although almost two-thirds of them do not experience a transition to psychosis, they still exhibit functional disabilities. Other subjective developmental features may be useful for a more precise identification of individuals at UHR. Avoidant behaviors are consistently reported in schizophrenia and in UHR individuals and may be the reflection of a pattern of personality. Thus, personality features in UHR individuals deserves further research. The objective of the present study was to compare temperament and character dimensions between UHR individuals, patients with schizophrenia and healthy controls. One hundred participants (25 UHR individuals, 25 schizophrenia patients and 50 control subjects) where evaluated with the Temperament and Character Inventory-Revised (TCI-R). Univariate ANOVAs followed by Bonferroni tests were used. UHR individuals and schizophrenia patients exhibited higher levels of Harm Avoidance (HA) when compared to control subjects. For HA1 Anticipatory worry vs Uninhibited optimism and HA4 Fatigability & asthenia, UHR and schizophrenia groups showed similar scores and both groups were higher compared to control subjects. With respect to Cooperativeness (CO), UHR and schizophrenia reported lower scores than control subjects, in particular CO2 Empathy vs Social disinterest and CO3 Helpfulness vs unhelpfulness. This study replicates and extends the consideration of HA as a psychopathological related endophenotype and gives us further information of the possible role of personality features in the expression of some of the social dysfunctions observed both in prodromal subjects and schizophrenia patients. Copyright © 2014 Elsevier Ltd. All rights reserved.

Borderline personality pathology in young people at ultra high risk of developing a psychotic disorder.

Science.gov (United States)

Ryan, Jaymee; Graham, Anne; Nelson, Barnaby; Yung, Alison

2017-06-01

The association between borderline personality disorder and the ultra high risk (UHR) for psychosis state is unclear. The following study aimed to investigate the type of attenuated psychotic symptoms and prevalence of borderline personality pathology in a sample of UHR young people. Additionally, the study aimed to explore whether borderline personality pathology influenced the transition rate to psychosis. Medical records from Orygen Youth Health between 2007 and 2009 were examined. There were 180 patients who met UHR criteria and were included for analysis. Most patients were females (62.8%) and age ranged from 15 to 24 years. A quarter (25.2%) of UHR patients endorsed items consistent with borderline personality pathology. UHR patients with borderline personality pathology experienced a range of attenuated psychotic symptoms and could not be statistically differentiated from UHR patients with less significant or without borderline personality pathology. Borderline personality pathology did not increase or decrease the risk of developing a psychotic disorder. The absence of depression was the only predictor of psychosis. Many UHR patients present with concurrent borderline personality features. The psychotic experiences reported by UHR patients with borderline personality features were not limited to paranoid ideation, supporting the idea that borderline personality disorder may include a wider range of psychotic symptoms than previously thought. It is further possible that the psychotic symptoms experienced in this group could also be indicative of an emerging psychotic disorder. © 2015 Wiley Publishing Asia Pty Ltd.

Mathematisches Bewusstsein

Science.gov (United States)

Kaenders, Rainer; Kvasz, Ladislav

Wenn jemand sagt, dass ein Bus um 9 Uhr abfährt - weiß man es dann? Angenommen, man ist darüber unterrichtet, dass die Busse unter der Woche immer zur vollen Stunde abfahren - von 7 Uhr morgens bis 7 Uhr abends, weiß man es dann mit dem Wissen um diese allgemeine Regel besser, dass der Bus um 9 Uhr abfährt? Macht es einen Unterschied, ob man den Fahrplan erstellt, den Bus lenkt oder nur mitfährt, um sich dieser Tatsache bewusst zu sein?

EPA guidance on the early detection of clinical high risk states of psychoses

DEFF Research Database (Denmark)

Schultze-Lutter, F; Michel, C; Schmidt, S J

2015-01-01

The aim of this guidance paper of the European Psychiatric Association is to provide evidence-based recommendations on the early detection of a clinical high risk (CHR) for psychosis in patients with mental problems. To this aim, we conducted a meta-analysis of studies reporting on conversion rates...... to psychosis in non-overlapping samples meeting any at least any one of the main CHR criteria: ultra-high risk (UHR) and/or basic symptoms criteria. Further, effects of potential moderators (different UHR criteria definitions, single UHR criteria and age) on conversion rates were examined. Conversion rates...... in the identified 42 samples with altogether more than 4000 CHR patients who had mainly been identified by UHR criteria and/or the basic symptom criterion 'cognitive disturbances' (COGDIS) showed considerable heterogeneity. While UHR criteria and COGDIS were related to similar conversion rates until 2-year follow...

Towards a Standard Psychometric Diagnostic Interview for Subjects at Ultra High Risk of Psychosis: CAARMS versus SIPS

Science.gov (United States)

Fusar-Poli, P.; Cappucciati, M.; Rutigliano, G.; Lee, T. Y.; Beverly, Q.; Bonoldi, I.; Lelli, J.; Kaar, S. J.; Gago, E.; Rocchetti, M.; Patel, R.; Bhavsar, V.; Tognin, S.; Badger, S.; Calem, M.; Lim, K.; Kwon, J. S.; Perez, J.; McGuire, P.

2016-01-01

Background. Several psychometric instruments are available for the diagnostic interview of subjects at ultra high risk (UHR) of psychosis. Their diagnostic comparability is unknown. Methods. All referrals to the OASIS (London) or CAMEO (Cambridgeshire) UHR services from May 13 to Dec 14 were interviewed for a UHR state using both the CAARMS 12/2006 and the SIPS 5.0. Percent overall agreement, kappa, the McNemar-Bowker χ 2 test, equipercentile methods, and residual analyses were used to investigate diagnostic outcomes and symptoms severity or frequency. A conversion algorithm (CONVERT) was validated in an independent UHR sample from the Seoul Youth Clinic (Seoul). Results. There was overall substantial CAARMS-versus-SIPS agreement in the identification of UHR subjects (n = 212, percent overall agreement = 86%; kappa = 0.781, 95% CI from 0.684 to 0.878; McNemar-Bowker test = 0.069), with the exception of the brief limited intermittent psychotic symptoms (BLIPS) subgroup. Equipercentile-linking table linked symptoms severity and frequency across the CAARMS and SIPS. The conversion algorithm was validated in 93 UHR subjects, showing excellent diagnostic accuracy (CAARMS to SIPS: ROC area 0.929; SIPS to CAARMS: ROC area 0.903). Conclusions. This study provides initial comparability data between CAARMS and SIPS and will inform ongoing multicentre studies and clinical guidelines for the UHR psychometric diagnostic interview. PMID:27314005

Towards a Standard Psychometric Diagnostic Interview for Subjects at Ultra High Risk of Psychosis: CAARMS versus SIPS

Directory of Open Access Journals (Sweden)

P. Fusar-Poli

2016-01-01

Full Text Available Background. Several psychometric instruments are available for the diagnostic interview of subjects at ultra high risk (UHR of psychosis. Their diagnostic comparability is unknown. Methods. All referrals to the OASIS (London or CAMEO (Cambridgeshire UHR services from May 13 to Dec 14 were interviewed for a UHR state using both the CAARMS 12/2006 and the SIPS 5.0. Percent overall agreement, kappa, the McNemar-Bowker χ2 test, equipercentile methods, and residual analyses were used to investigate diagnostic outcomes and symptoms severity or frequency. A conversion algorithm (CONVERT was validated in an independent UHR sample from the Seoul Youth Clinic (Seoul. Results. There was overall substantial CAARMS-versus-SIPS agreement in the identification of UHR subjects (n=212, percent overall agreement = 86%; kappa = 0.781, 95% CI from 0.684 to 0.878; McNemar-Bowker test = 0.069, with the exception of the brief limited intermittent psychotic symptoms (BLIPS subgroup. Equipercentile-linking table linked symptoms severity and frequency across the CAARMS and SIPS. The conversion algorithm was validated in 93 UHR subjects, showing excellent diagnostic accuracy (CAARMS to SIPS: ROC area 0.929; SIPS to CAARMS: ROC area 0.903. Conclusions. This study provides initial comparability data between CAARMS and SIPS and will inform ongoing multicentre studies and clinical guidelines for the UHR psychometric diagnostic interview.

Attenuated psychotic and basic symptom characteristics in adolescents with ultra-high risk criteria for psychosis, other non-psychotic psychiatric disorders and early-onset psychosis.

Science.gov (United States)

Lo Cascio, Nella; Saba, Riccardo; Hauser, Marta; Vernal, Ditte Lammers; Al-Jadiri, Aseel; Borenstein, Yehonatan; Sheridan, Eva M; Kishimoto, Taishiro; Armando, Marco; Vicari, Stefano; Fiori Nastro, Paolo; Girardi, Paolo; Gebhardt, Eva; Kane, John M; Auther, Andrea; Carrión, Ricardo E; Cornblatt, Barbara A; Schimmelmann, Benno G; Schultze-Lutter, Frauke; Correll, Christoph U

2016-10-01

While attenuated psychotic symptoms (APS) and basic symptoms (BS) are the main current predictors of psychosis in adults, studies in adolescents are scarce. Thus, we (1) described the prevalence and severity of positive, negative, disorganization, general, and basic symptoms in adolescent patients at ultra-high risk for psychosis (UHR), with other non-psychotic psychiatric disorders (PC) and with early-onset psychosis (EOP); and (2) investigated BS criteria in relation to UHR criteria. Sixty-nine 12-18-year-old adolescents (15.3 ± 1.7 years, female = 58.0 %, UHR = 22, PC = 27, EOP = 20) were assessed with the structured interview for prodromal syndromes (SIPS) and the schizophrenia proneness instrument-child and youth version (SPI-CY). Despite similar current and past 12-month global functioning, both UHR and EOP had significantly higher SIPS total and subscale scores compared to PC, with moderate-large effect sizes. Expectedly, UHR had significantly lower SIPS positive symptom scores than EOP, but similar SIPS negative, disorganized, and general symptom scores. Compared to PC, both EOP and UHR had more severe basic thought and perception disturbances, and significantly more often met cognitive disturbances criteria (EOP = 50.0 %, UHR = 40.9 %, PC = 14.8 %). Compared to UHR, both EOP and PC significantly less often met cognitive-perceptive BS criteria (EOP = 35.0 %, UHR = 68.2 %, PC = 25.9 %). BS were significantly more prevalent in both EOP and UHR than PC, and UHR were similar to EOP in symptom domains. Given the uncertain outcome of adolescents at clinical high-risk of psychosis, future research is needed to determine whether the combined assessment of early subjective disturbances with observable APS can improve the accuracy of psychosis prediction.

Landscape consequences of natural gas extraction in Lackawanna and Wayne Counties, Pennsylvania, 2004-2010

Science.gov (United States)

Milheim, L.E.; Slonecker, E.T.; Roig-Silva, C.M.; Malizia, A.R.

2013-01-01

Increased demands for cleaner burning energy, coupled with the relatively recent technological advances in accessing unconventional hydrocarbon-rich geologic formations, have led to an intense effort to find and extract natural gas from various underground sources around the country. One of these sources, the Marcellus Shale, located in the Allegheny Plateau, is currently undergoing extensive drilling and production. The technology used to extract gas in the Marcellus Shale is known as hydraulic fracturing and has garnered much attention because of its use of large amounts of fresh water, its use of proprietary fluids for the hydraulic-fracturing process, its potential to release contaminants into the environment, and its potential effect on water resources. Nonetheless, development of natural gas extraction wells in the Marcellus Shale is only part of the overall natural gas story in this area of Pennsylvania. Conventional natural gas wells, which sometimes use the same technique, are commonly located in the same general area as the Marcellus Shale and are frequently developed in clusters across the landscape. The combined effects of these two natural gas extraction methods create potentially serious patterns of disturbance on the landscape. This document quantifies the landscape changes and consequences of natural gas extraction for Lackawanna County and Wayne County in Pennsylvania between 2004 and 2010. Patterns of landscape disturbance related to natural gas extraction activities were collected and digitized using National Agriculture Imagery Program (NAIP) imagery for 2004, 2005/2006, 2008, and 2010. The disturbance patterns were then used to measure changes in land cover and land use using the National Land Cover Database (NLCD) of 2001. A series of landscape metrics is also used to quantify these changes and is included in this publication.

Results of the mobile gamma scanning activities in Wayne and Pequannock Townships, New Jersey

International Nuclear Information System (INIS)

Johnson, C.A.; Roberts, D.A.; Patania, V.P.; Foley, R.D.

1994-01-01

During the early 1980s the W. R. Grace site and the adjacent area were the focus of several radiological investigations. Radiological surveys revealed surface radionuclide concentrations greater than those acceptable under US Department of Energy (DOE) remedial action guidelines. In 1984, Congress assigned responsibility for cleanup of the W.R. Grace site to the Department of Energy. The property was redesignated as the Wayne Interim Storage Site (WISS) and in 1985 DOE began plans for survey/monitoring, and remedial action of nearby vicinity properties and the interim storage site. Evaluations of the radiological survey data in 1986 indicated radioactive contamination above current DOE guidelines at the off-site areas of parts of Township Park southwest of WISS, and parts of the Sheffield Brook area and railroad siding in Pequannock Township. Remedial action was conducted over several years of most of these areas and independent verification of remedial action was performed. A team from Oak Ridge National Laboratory conducted a mobile radiological scanning survey of a stretch of public roadway in the immediate vicinity south of the WISS, extending northwest to the Pompton turnpike. A mobile gamma scanning van with an on-board computer system was used to identify at least 24 anomalous areas, some attributable to the naturally elevated levels in concrete, asphalt, and natural granite found in streets, driveways and landscaping materials in the area. Analyses of the biased soil samples taken in the ballpark also revealed slightly elevated thorium concentrations. However, soil concentration measurements when averaged over 100 m 2 fall below the limits prescribed by DOE radiological guidelines established for this site. The anomalies may result from a wide range of sources, such as ash, granite, and fertilizer as well as materials from the former Grace facility

Social cognition deficits and the 'ultra high risk' for psychosis population: a review of literature.

Science.gov (United States)

Thompson, Andrew D; Bartholomeusz, Cali; Yung, Alison R

2011-08-01

A number of risk factors for developing a psychotic disorder have been investigated in the 'ultra high risk' (UHR) population, including neurocognitive abilities, social functioning and, more recently, social cognition. We aimed to review the literature on social cognition in the UHR population. Literature was restricted to English articles and identified using Pubmed, Medline, PsychINFO and CINAHLplus, as well as the reference lists of published studies and reviews. Search terms included social cognition, theory of mind, emotion recognition, attributional style, social knowledge, social perception, 'at risk mental state', psychosis prodrome 'clinical high risk' and 'ultra high risk'. Inclusion criteria were an outcome measure of a social cognition task and an UHR population defined by a structured validated instrument. Seven original research articles met the inclusion criteria, one of which was a conference abstract. One of the two studies that assessed theory of mind, two of the four studies that assessed emotion recognition and both the two studies that assessed social perception/knowledge found significant deficits in UHR patients. The single study that assessed attributional bias also reported differences in UHR patients compared with healthy controls. There is limited published literature on social cognitive performance in the UHR population. Despite this, deficits in certain social cognitive abilities do appear to be present, but further research with more reliable cross-cultural measures is needed. The characterization of social cognitive deficits in the UHR populations may aid in the identification of potential markers for development of a subsequent psychotic disorder, as well as targets for early intervention. © 2011 Blackwell Publishing Asia Pty Ltd.

Premorbid adjustment in individuals at ultra-high risk for developing psychosis

DEFF Research Database (Denmark)

Dannevang, Anders; Randers, Lasse; Gondan, Matthias

2017-01-01

between childhood and early adolescence. The UHR individuals had more premorbid adjustment difficulties on both the social and academic scale, and on the individual PAS scales. Conclusion: From childhood UHR individuals have lower levels of social and academic premorbid adjustment compared to healthy...... and academic scales were computed. Results: Compared to the healthy controls the UHR individuals’ social and academic premorbid adjustment declined across age periods. Social premorbid adjustment declined particularly between late adolescence and adulthood. Academic premorbid adjustment declined particularly...

Social cognition in patients at ultra-high risk for psychosis: What is the relation to social skills and functioning?

Directory of Open Access Journals (Sweden)

Louise B. Glenthøj

2016-09-01

Conclusion: Significant impairments in social cognition and social skills were found in UHR patients. The patients' social cognitive function was associated with overall functioning and social skills. Negative symptoms appear to play an important role for functioning. Research is needed to investigate how the relations between social cognition, social skills and functioning develop from the UHR state to the stage of manifest illness. Research into how deficits in social cognition and social skills can be ameliorated in UHR patients is warranted.

In situ ultrahigh-resolution optical coherence tomography characterization of eye bank corneal tissue processed for lamellar keratoplasty.

Science.gov (United States)

Brown, Jamin S; Wang, Danling; Li, Xiaoli; Baluyot, Florence; Iliakis, Bernie; Lindquist, Thomas D; Shirakawa, Rika; Shen, Tueng T; Li, Xingde

2008-08-01

To use optical coherence tomography (OCT) as a noninvasive tool to perform in situ characterization of eye bank corneal tissue processed for lamellar keratoplasty. A custom-built ultrahigh-resolution OCT (UHR-OCT) was used to characterize donor corneal tissue that had been processed for lamellar keratoplasty. Twenty-seven donor corneas were analyzed. Four donor corneas were used as controls, whereas the rest were processed into donor corneal buttons for lamellar transplantation by using hand dissection, a microkeratome, or a femtosecond laser. UHR-OCT was also used to noninvasively characterize and monitor the viable corneal tissue immersed in storage medium over 3 weeks. The UHR-OCT captured high-resolution images of the donor corneal tissue in situ. This noninvasive technique showed the changes in donor corneal tissue morphology with time while in storage medium. The characteristics of the lamellar corneal tissue with each processing modality were clearly visible by UHR-OCT. The in situ characterization of the femtosecond laser-cut corneal tissue was noted to have more interface debris than shown by routine histology. The effects of the femtosecond laser microcavitation bubbles on the corneal tissue were well visualized at the edges of the lamellar flap while in storage medium. The results of our feasibility study show that UHR-OCT can provide superb, in situ microstructural characterization of eye bank corneal tissue noninvasively. The UHR-OCT interface findings and corneal endothelial disc thickness uniformity analysis are valuable information that may be used to optimize the modalities and parameters for lamellar tissue processing. The UHR-OCT is a powerful approach that will allow us to further evaluate the tissue response to different processing techniques for posterior lamellar keratoplasty. It may also provide information that can be used to correlate with postoperative clinical outcomes. UHR-OCT has the potential to become a routine part of tissue

The FOCUS trial

DEFF Research Database (Denmark)

Glenthøj, Louise B; Fagerlund, Birgitte; Randers, Lasse

2015-01-01

BACKGROUND: Cognitive deficits are a distinct feature among people at ultra-high risk (UHR) for psychosis and pose a barrier to functional recovery. Insufficient evidence exists on how to ameliorate these cognitive deficits in patients at UHR for psychosis and hence improve daily living and quality...... of life. The aim of the trial is to investigate whether cognitive remediation can improve cognitive and psychosocial function in patients at UHR for psychosis. METHODS: The FOCUS trial (Function and Overall Cognition in Ultra-high risk States) is a randomised, parallel group, observer-blinded clinical...... trial enrolling 126 patients meeting the standardised criteria of being at UHR for psychosis. Patients are recruited from psychiatric in- and outpatient facilities in the Copenhagen catchment area. Patients are randomised to one of the two treatment arms: cognitive remediation plus standard treatment...

T174. STRUCTURAL ABNORMALITIES IN THE CINGULATE CORTEX IN ADOLESCENTS AT ULTRA-HIGH RISK WHO LATER DEVELOP PSYCHOSIS

Science.gov (United States)

Fortea, Adriana; van Eindhjoven, Phillip; Pariente, Jose; Calvo, Anna; Batalla, Albert; de la Serna, Elena; Ilzarbe, Daniel; Tor, Jordina; Dolz, Montserrat; Baeza, Inmaculada; Sugranyes, Gisela

2018-01-01

Abstract Background Identification of biomarkers of transition to psychosis in individuals at ultra-high risk (UHR) has the potential to improve future outcomes (McGorry, 2008). Structural MRI studies with UHR samples have revealed steeper rates of cortical thinning in temporal, prefrontal and cingulate cortices in individuals who later develop psychosis in both baseline and longitudinal comparisons (Fusar-Poli, 2011; Cannon, 2014). However, little is known about how onset of prodromal symptoms during adolescence impacts on changes in cortical thickness (CTH) (Ziermans, 2012). Methods Multicentre cross-sectional case-control study, including youth aged 10–17 years, recruited from two child and adolescent mental health centres. UHR individuals were identified using the Structured Interview for Prodromal Syndromes criteria with some modifications. Healthy controls (HC) were recruited from the same geographical area. Exclusion criteria comprised personal history of psychotic symptoms, IQ.6) for CTH measures. Images were pre-processed employing automated procedures implemented in FreeSurfer 5.3.0, cortical parcellation employed the Desikan-Killiany brain atlas. Analyses: First, mean global and lobar (frontal, parietal, temporal, occipital, insula and cingulate) CTH measurements were computed. Then, within lobes showing group effects, CTH was measured for each parcellation. ANCOVA was performed to test differences between groups in SPSS 22.0, including gender, age, total intracranial volume and site as covariates. Significance was set at p<.05, corrected using the false discovery rate (FDR). Results 122 subjects were included (59 UHR-NP vs. 18 UHR-P vs. 45 HC, mean ages: 15.2 ± 1.5 vs. 15.0 ± 1.8 vs. 15.8 ± 1.5, F=1.9, p=.15; gender (%female): 61.0% vs 61.1% vs 68.9%, χ2=.76, p=.68). There were no significant differences in case-control proportion between centres: χ2=1.3, p=.25. No significant differences in global CTH in UHR-P (2.57 ± 0.13mm) relative to UHR

Progressive Decline in Hippocampal CA1 Volume in Individuals at Ultra-High-Risk for Psychosis Who Do Not Remit: Findings from the Longitudinal Youth at Risk Study.

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Ho, New Fei; Holt, Daphne J; Cheung, Mike; Iglesias, Juan Eugenio; Goh, Alex; Wang, Mingyuan; Lim, Joseph Kw; de Souza, Joshua; Poh, Joann S; See, Yuen Mei; Adcock, Alison R; Wood, Stephen J; Chee, Michael Wl; Lee, Jimmy; Zhou, Juan

2017-05-01

Most individuals identified as ultra-high-risk (UHR) for psychosis do not develop frank psychosis. They continue to exhibit subthreshold symptoms, or go on to fully remit. Prior work has shown that the volume of CA1, a subfield of the hippocampus, is selectively reduced in the early stages of schizophrenia. Here we aimed to determine whether patterns of volume change of CA1 are different in UHR individuals who do or do not achieve symptomatic remission. Structural MRI scans were acquired at baseline and at 1-2 follow-up time points (at 12-month intervals) from 147 UHR and healthy control subjects. An automated method (based on an ex vivo atlas of ultra-high-resolution hippocampal tissue) was used to delineate the hippocampal subfields. Over time, a greater decline in bilateral CA1 subfield volumes was found in the subgroup of UHR subjects whose subthreshold symptoms persisted (n=40) and also those who developed clinical psychosis (n=12), compared with UHR subjects who remitted (n=41) and healthy controls (n=54). No baseline differences in volumes of the overall hippocampus or its subfields were found among the groups. Moreover, the rate of volume decline of CA1, but not of other hippocampal subfields, in the non-remitters was associated with increasing symptom severity over time. Thus, these findings indicate that there is deterioration of CA1 volume in persistently symptomatic UHR individuals in proportion to symptomatic progression.

Les barrières à une bonne prise en charge des diabétiques dans les structures de première ligne de la province de Khouribga (MAROC)

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Hassoune, Samira; Badri, Soufiane; Nani, Samira; Belhadi, Leila; Maaroufi, Abderrahmane

2012-01-01

Introduction Le diabète constitue un important enjeu de santé publique au Maroc et représente un défi auquel les médecins généralistes sont confrontés dans leur pratique quotidienne. Le but de ce travail était de décrire les barrières entravant une bonne prise en charge des patients diabétiques dans les structures de 1ère ligne de la province de khouribga. Méthodes Il s'agit d'une étude transversale menée de décembre 2010 à mars 2011, chez les 54 médecins généralistes (MG) exerçants dans les centres de santé de la province. La collecte des données a été réalisée à l'aide d'un questionnaire prétesté et auto administré et la saisie et l'analyse effectuées sur le logiciel SPSS 16. Résultats Huit pourcent des MG disposaient de registre informatisé pour le suivi des diabétiques. Les principales barrières à une prise en charge correcte des patients étaient le statut socio-économique faible des patients (94%), leur niveau scolaire bas (86%), le manque de moyens de traitement et de suivi (80%), le nombre insuffisant de diabétologues (80%), le manque de coordination avec les structures de 2ème ligne (74%) et l'insuffisance des séminaires de formation continue (58%). Conclusion Les médecins généralistes sont confrontés à de nombreux obstacles concernant la prise en charge des patients diabétiques. L’équipement des centres de santé en moyens diagnostiques et thérapeutiques suffisants, l'amélioration de l'accessibilité des diabétiques aux soins et la formation continue des médecins pourraient être des solutions pour améliorer cette prise en charge surtout devant la pénurie de spécialistes dans notre pays. PMID:23330033

Intrinsic Functional Connectivity in Salience and Default Mode Networks and Aberrant Social Processes in Youth at Ultra-High Risk for Psychosis.

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Pelletier-Baldelli, Andrea; Bernard, Jessica A; Mittal, Vijay A

2015-01-01

Social processes are key to navigating the world, and investigating their underlying mechanisms and cognitive architecture can aid in understanding disease states such as schizophrenia, where social processes are highly impacted. Evidence suggests that social processes are impaired in individuals at ultra high-risk for the development of psychosis (UHR). Understanding these phenomena in UHR youth may clarify disease etiology and social processes in a period that is characterized by significantly fewer confounds than schizophrenia. Furthermore, understanding social processing deficits in this population will help explain these processes in healthy individuals. The current study examined resting state connectivity of the salience (SN) and default mode networks (DMN) in association with facial emotion recognition (FER), an integral aspect of social processes, as well as broader social functioning (SF) in UHR individuals and healthy controls. Consistent with the existing literature, UHR youth were impaired in FER and SF when compared with controls. In the UHR group, we found increased connectivity between the SN and the medial prefrontal cortex, an area of the DMN relative to controls. In UHR youth, the DMN exhibited both positive and negative correlations with the somatosensory cortex/cerebellum and precuneus, respectively, which was linked with better FER performance. For SF, results showed that sensory processing links with the SN might be important in allowing for better SF for both groups, but especially in controls where sensory processing is likely to be unimpaired. These findings clarify how social processing deficits may manifest in psychosis, and underscore the importance of SN and DMN connectivity for social processing more generally.

Visualization and tissue classification of human breast cancer images using ultrahigh-resolution OCT (Conference Presentation)

Science.gov (United States)

Yao, Xinwen; Gan, Yu; Chang, Ernest W.; Hibshoosh, Hanina; Feldman, Sheldon; Hendon, Christine P.

2017-02-01

We employed a home-built ultrahigh resolution (UHR) OCT system at 800nm to image human breast cancer sample ex vivo. The system has an axial resolution of 2.72µm and a lateral resolution of 5.52µm with an extended imaging range of 1.78mm. Over 900 UHR OCT volumes were generated on specimens from 23 breast cancer cases. With better spatial resolution, detailed structures in the breast tissue were better defined. Different types of breast cancer as well as healthy breast tissue can be well delineated from the UHR OCT images. To quantitatively evaluate the advantages of UHR OCT imaging of breast cancer, features derived from OCT intensity images were used as inputs to a machine learning model, the relevance vector machine. A trained machine learning model was employed to evaluate the performance of tissue classification based on UHR OCT images for differentiating tissue types in the breast samples, including adipose tissue, healthy stroma and cancerous region. For adipose tissue, grid-based local features were extracted from OCT intensity data, including standard deviation, entropy, and homogeneity. We showed that it was possible to enhance the classification performance on distinguishing fat tissue from non-fat tissue by using the UHR images when compared with the results based on OCT images from a commercial 1300 nm OCT system. For invasive ductal carcinoma (IDC) and normal stroma differentiation, the classification was based on frame-based features that portray signal penetration depth and tissue reflectivity. The confusing matrix indicated a sensitivity of 97.5% and a sensitivity of 77.8%.

Impact of rurality and substance use on young people at ultra high risk for psychosis.

Science.gov (United States)

Stain, Helen J; Halpin, Sean A; Baker, Amanda L; Startup, Mike; Carr, Vaughan J; Schall, Ulrich; Crittenden, Kylie; Clark, Vanessa; Lewin, Terry J; Bucci, Sandra

2017-07-26

Longitudinal research into early intervention for youth at ultra high risk (UHR) for psychosis demonstrates beneficial outcomes including increased treatment compliance and greater participation in education and the workforce. Despite known barriers for rural youth accessing mental health services, research comparing urban and rural UHR youth is lacking. The study included an examination of the impact of substance use on functioning of UHR youth. Youth aged 12 to 25 years were recruited from the urban area of Newcastle or the rural area of Orange, New South Wales, Australia, and identified as UHR by the Comprehensive Assessment of At Risk Mental States. Rural and urban youth were compared on clinical profiles, social and occupational functioning and substance use. The rural youth showed different help-seeking behaviours and had greater functional impairment than urban youth. Substance use was common across the sample of 57 youth (mean age 16.5 years, 56% female) and a history of hazardous substance use was associated with higher levels of depression. Rural youth (n = 32) were more likely than urban youth to be taking antidepressants at baseline (44% compared with 16%). Different patterns of help seeking by rural UHR youth suggest a need for greater access to psychosis informed primary care early intervention services. Interventions should target functional decline to prevent adverse outcomes such as reduced community participation and unemployment. In addition, interventions for substance use should be a priority for UHR youth, who should also be screened and monitored for depressive symptoms and treated for depression if indicated. © 2017 John Wiley & Sons Australia, Ltd.

Differences in omega-3 and omega-6 polyunsaturated fatty acid consumption in people at ultra-high risk of psychosis, first-episode schizophrenia, and in healthy controls.

Science.gov (United States)

Pawełczyk, Tomasz; Trafalska, Elżbieta; Pawełczyk, Agnieszka; Kotlicka-Antczak, Magdalena

2017-12-01

Supplementation with omega-3 PUFA showed efficacy in reducing the risk of transition into psychosis in UHR individuals. It is uncertain whether dietary patterns can be partly responsible for n-3 deficiencies observed in susceptible participants before the diagnosis of schizophrenia. The study was designed to assess differences in omega-3 and omega-6 PUFA consumption in healthy controls (HC), UHR participants and FES patients as well as to verify the hypothesis that dietary changes in PUFA consumption are present before active psychosis develops, that is, in UHR individuals. Dietary habits during the previous year were assessed in 34 patients at UHR of psychosis, 33 patients diagnosed with FES and 33 HC participants using a validated Food-Frequency Questionnaire and the Polish Food Composition Tables. Significant differences in omega-3 and omega-6 PUFA intake were observed between study groups. UHR and FES groups reported significantly higher consumption of omega-6 PUFA in comparison with HC. FES patients also reported a higher consumption of alpha-linolenic acid (omega-3) in comparison with HC. No significant differences were seen in consumption of long-chain marine PUFA. Differences in omega-6 and omega-3 PUFA consumption exist before development of psychotic symptoms, fulfilling the criteria of schizophrenia. © 2015 Wiley Publishing Asia Pty Ltd.

Social relationships in young adults at ultra high risk for psychosis.

Science.gov (United States)

Robustelli, Briana L; Newberry, Raeana E; Whisman, Mark A; Mittal, Vijay A

2017-01-01

Studies suggest that individuals with schizophrenia have smaller social networks and less satisfying relationships. However, much is still unknown about the typical quantity and quality of social relationships in young adults during the ultra high-risk (UHR) period. Investigating these relationships holds significant importance for improving understanding of etiological processes, mapping the social environment, and highlighting treatment targets in a critical period. A total of 85 participants (44 UHR and 41 healthy controls) completed measures examining the participants' social relationships, social support, and loneliness. Mean differences between the UHR and healthy control participants and associations between social relationships and symptoms and functioning were examined. Results indicated significant differences between groups on several indices. Specifically, the UHR youth reported fewer close friends, less diverse social networks, less perceived social support, poorer relationship quality with family and friends, and more loneliness. Notably, within the UHR group, being lonely and having fewer and worse quality relationships was associated with greater symptom severity and lower overall functioning. This study suggests that youth at high-risk of developing psychosis have fewer and poorer quality social relationships. Interventions that focus on increasing the quantity and quality of young adults' social networks may be beneficial for this population. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Factor analysis of the scale of prodromal symptoms: differentiating between negative and depression symptoms

NARCIS (Netherlands)

Klaassen, Rianne M. C.; Velthorst, Eva; Nieman, Dorien H.; de Haan, Lieuwe; Becker, Hiske E.; Dingemans, Peter M.; van de Fliert, J. Reinaud; van der Gaag, Mark; Linszen, Don H.

2011-01-01

This study examines the ability of the Scale of Prodromal Symptoms (SOPS) to differentiate between negative and depression symptoms in a young help-seeking ultrahigh risk (UHR) group. SOPS data of 77 help-seeking patients at UHR for psychosis were analyzed with an exploratory factor analysis. The

Microstructural abnormalities in MEWDS demonstrated by ultrahigh resolution optical coherence tomography.

Science.gov (United States)

Nguyen, My Hanh T; Witkin, Andre J; Reichel, Elias; Ko, Tony H; Fujimoto, James G; Schuman, Joel S; Duker, Jay S

2007-01-01

Histopathological studies of acute multiple evanescent white dot syndrome (MEWDS) have not been reported because of the transient and benign nature of the disease. Ultrahigh resolution optical coherence tomography (UHR-OCT), capable of high resolution in vivo imaging, offers a unique opportunity to visualize retinal microstructure in the disease. UHR-OCT images of the maculae of five patients with MEWDS were obtained and analyzed. Diagnosis was based on clinical presentation, examination, visual field testing, and angiography. UHR-OCT revealed disturbances in the photoreceptor inner/outer segment junction (IS/OS) in each of the five patients (six eyes) with MEWDS. In addition, thinning of the outer nuclear layer was seen in the case of recurrent MEWDS, suggesting that repeated episodes of MEWDS may result in photoreceptor atrophy. Subtle disruptions of the photoreceptor IS/OS are demonstrated in all eyes affected by MEWDS. UHR-OCT may be a useful adjunct to diagnosis and monitoring of MEWDS.

RADAR upper hybrid resonance scattering diagnostics of small-scale fluctuations and waves in tokamak plasmas

International Nuclear Information System (INIS)

Bulyiginskiy, D.G.; Gurchenko, A.D.; Gusakov, E.Z.; Korkin, V.V.; Larionov, M.M.; Novik, K.M.; Petrov, Yu.V.; Popov, A.Yu.; Saveliev, A.N.; Selenin, V.L.; Stepanov, A.Yu.

2001-01-01

The upper hybrid resonance (UHR) scattering technique possessing such merits as one-dimensional probing geometry, enhancement of cross section, and fine localization of scattering region is modified in the new diagnostics under development to achieve wave number resolution. The fluctuation wave number is estimated in the new technique from the scattering signal time delay measurements. The feasibility of the scheme is checked in the proof of principal experiment in a tokamak. The time delay of the UHR scattering signal exceeding 10 ns is observed. The small scale low frequency density fluctuations are investigated in the UHR RADAR backscattering experiment. The UHR cross-polarization scattering signal related to small scale magnetic fluctuations is observed. The lower hybrid (LH) wave propagation and both linear and nonlinear wave conversion are investigated. The small wavelength (λ≤0.02 cm) high number ion Bernstein harmonics, resulting from the linear wave conversion of the LH wave are observed in a tokamak plasma for the first time

Social cognition in patients at ultra-high risk for psychosis: What is the relation to social skills and functioning?

Science.gov (United States)

Glenthøj, Louise B; Fagerlund, Birgitte; Hjorthøj, Carsten; Jepsen, Jens R M; Bak, Nikolaj; Kristensen, Tina D; Wenneberg, Christina; Krakauer, Kristine; Roberts, David L; Nordentoft, Merete

2016-09-01

Patients at ultra-high risk (UHR) for psychosis show significant impairments in functioning. It is essential to determine which factors influence functioning, as it may have implications for intervention strategies. This study examined whether social cognitive abilities and clinical symptoms are associated with functioning and social skills. The study included 65 UHR patients and 30 healthy controls. Social cognitive function, social skills, and a broad range of functioning measures were assessed. The UHR patients demonstrated significant decrements on The Awareness of Social Inferences Task total score (p = .046, d  = .51), and on the CANTAB emotion recognition task total percent correct (p = .023, d  = .54) displaying particular difficulties in negative affect recognition. The patients exhibited significant impairments in social skills measured with the High Risk Social Challenge (p˂.001, d  = 1.05). Aspects of emotion recognition were associated with role functioning and social skill performance. The level of attributional bias was associated with overall functioning, and theory of mind ability was associated with self-reported functioning. Negative symptoms were associated with all measures of functioning (p ≤ .05). Significant impairments in social cognition and social skills were found in UHR patients. The patients' social cognitive function was associated with overall functioning and social skills. Negative symptoms appear to play an important role for functioning. Research is needed to investigate how the relations between social cognition, social skills and functioning develop from the UHR state to the stage of manifest illness. Research into how deficits in social cognition and social skills can be ameliorated in UHR patients is warranted.

Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention

Directory of Open Access Journals (Sweden)

Flynn Darran

2012-08-01

Full Text Available Abstract Background The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of young offenders one would expect to find a high prevalence of individuals with pre-psychotic or ultra-high risk mental states for psychosis (UHR. Accordingly young offender institutions offer an opportunity for early interventions which could result in improved long term mental health, social and legal outcomes. In the course of establishing a mental health in-reach service into Ireland’s only young offender prison, we sought to estimate unmet mental health needs. Methods Every third new committal to a young offenders prison was interviewed using the Comprehensive Assessment of At-Risk Mental States (CAARMS to identify the Ultra High Risk (UHR state and a structured interview for assessing drug and alcohol misuse according to DSM-IV-TR criteria, the Developmental Understanding of Drug Misuse and Dependence - Short Form (DUNDRUM-S. Results Over a twelve month period 171 young male offenders aged 16 to 20 were assessed. Of these 39 (23%, 95% confidence interval 18% to 30% met UHR criteria. UHR states peaked at 18 years, were associated with lower SOFAS scores for social and occupational function and were also associated with multiple substance misuse. The relationship with lower SOFAS scores persisted even when co-varying for multiple substance misuse. Conclusions Although psychotic symptoms are common in community samples of children and adolescents, the prevalence of the UHR state in young offenders was higher than reported for community samples. The association with impaired function also suggests that this may be part of a developing disorder. Much more attention should be paid to the relationship of UHR states to substance misuse and to the health needs of young offenders.

Increased Internet use and poorer ability to manage emotions in youth at high-risk for psychosis

Directory of Open Access Journals (Sweden)

Andrea Pelletier-Baldelli

2015-12-01

Full Text Available The relationship between Internet use and social behavior remains unknown. However, research indicates that Internet use (IU may have some causal role in certain types of psychopathology and overall functioning. In contrast, other work suggests that IU may be protective and buffer against social isolation. Poorer emotional processing (EP is characteristic of schizophrenia, and these deficits are present prior to illness onset (the ultra high-risk period (UHR. UHR adolescents/young adults also fall within an age demographic characterized by extensive IU, which suggests that evaluating a link between IU and social behavior in this population may be especially informative. The present study examined the relationship between IU and emotional processing in 98 adolescents/young adults (52 UHR youth and 46 controls. UHR youth exhibited greater problematic IU (β = −6.49, F(1,95 = 8.79, p = 0.002 and social withdrawal/problems resulting from this use (β = −3.23, F(1,95 = 11.43, p < 0.001, as well deficits in emotional processing in comparison to healthy peers (β = 4.59, F(1,94 = 5.52, p = 0.011. Furthermore, the social problems resulting from IU were significantly related to the ability to process emotional information in the UHR group (β = −0.51, t(1,48 = −2.10, p = 0.021. UHR youth showed evidence of problematic IU relative to controls, and the social problems resulting from IU related to poorer EP. Findings replicate extant research involving other psychosis risk populations, while adding information regarding how social processes may relate to IU.

Resting cortisol level, self-concept, and putative familial environment in adolescents at ultra high-risk for psychotic disorders

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Carol, Emily E.; Mittal, Vijay A.

2015-01-01

Summary A growing body of evidence suggests that resting cortisol levels are elevated in patients with schizophrenia and closely tied to symptom severity. However, there is limited research on the biological stress system during the ultra high-risk (UHR) period immediately preceding the onset of psychosis, and cortisol has not been examined in relation to individual characteristics such as self-concept or potential stressors such as putative familial environment in this critical population. In the present study, salivary cortisol samples were collected on 37 UHR and 42 matched control adolescents, and these individuals were assessed with clinical interviews as well as a measure of self-concept. For a subsection of the sample (23 UHR and 20 control adolescents), a participating relative/caretaker was also assessed with an expressed emotion interview designed to gauge psychosocial environment. Consistent with previous studies, UHR participants exhibited elevated resting cortisol levels when compared with controls. In addition, UHR adolescents exhibited increased negative self-concept and their relatives/caretakers endorsed significantly fewer initial positive statements about the participant. Interestingly, a strong trend in the UHR group suggests that higher cortisol levels are associated with higher rates of critical statements from relatives/caretakers. Furthermore, elevated cortisol levels in the participants were associated with increased negative self-concept as well as fewer initial positive comments from relatives/caretakers. Results suggest that hypothalamic-pituitary-adrenal axis (HPA) dysfunction is closely associated with both individual and environmental-level characteristics. Taken together, these findings support a neural diathesis-stress model of psychosis and future studies, designed to examine causal relationships, stand to inform both our understanding of pathogenic processes in the high-risk period as well as early intervention efforts. PMID

Patients with first-episode, drug-naive schizophrenia and subjects at ultra-high risk of psychosis shared increased cerebellar-default mode network connectivity at rest.

Science.gov (United States)

Wang, Houliang; Guo, Wenbin; Liu, Feng; Wang, Guodong; Lyu, Hailong; Wu, Renrong; Chen, Jindong; Wang, Shuai; Li, Lehua; Zhao, Jingping

2016-05-18

Increased cerebellar-default mode network (DMN) connectivity has been observed in first-episode, drug-naive patients with schizophrenia. However, it remains unclear whether increased cerebellar-DMN connectivity starts earlier than disease onset. Thirty-four ultra-high risk (UHR) subjects, 31 first-episode, drug-naive patients with schizophrenia and 37 healthy controls were enrolled for a resting-state scan. The imaging data were analyzed using the seed-based functional connectivity (FC) method. Compared with the controls, UHR subjects and patients with schizophrenia shared increased connectivity between the right Crus I and bilateral posterior cingulate cortex/precuneus and between Lobule IX and the left superior medial prefrontal cortex. There are positive correlations between the right Crus I-bilateral precuneus connectivity and clinical variables (Structured Interview for Prodromal Syndromes/Positive and Negative Symptom Scale negative symptoms/total scores) in the UHR subjects. Increased cerebellar-DMN connectivity shared by the UHR subjects and the patients not only highlights the importance of the DMN in the pathophysiology of psychosis but also may be a trait alteration for psychosis.

Stream profile analysis using a step backwater model for selected reaches in the Chippewa Creek basin in Medina, Wayne, and Summit Counties, Ohio

Science.gov (United States)

Straub, David E.; Ebner, Andrew D.

2011-01-01

The USGS, in cooperation with the Chippewa Subdistrict of the Muskingum Watershed Conservancy District, performed hydrologic and hydraulic analyses for selected reaches of three streams in Medina, Wayne, Stark, and Summit Counties in northeast Ohio: Chippewa Creek, Little Chippewa Creek, and River Styx. This study was done to facilitate assessment of various alternatives for mitigating flood hazards in the Chippewa Creek basin. StreamStats regional regression equations were used to estimate instantaneous peak discharges approximately corresponding to bankfull flows. Explanatory variables used in the regression equations were drainage area, main-channel slope, and storage area. Hydraulic models were developed to determine water-surface profiles along the three stream reaches studied for the bankfull discharges established in the hydrologic analyses. The HEC-RAS step-backwater hydraulic analysis model was used to determine water-surface profiles for the three streams. Starting water-surface elevations for all streams were established using normal depth computations in the HEC-RAS models. Cross-sectional elevation data, hydraulic-structure geometries, and roughness coefficients were collected in the field and (along with peak-discharge estimates) used as input for the models. Reach-averaged reductions in water-surface elevations ranged from 0.11 to 1.29 feet over the four roughness coefficient reduction scenarios.

Antipsychotic interventions in prodromal psychosis: safety issues.

Science.gov (United States)

Liu, Chen-Chung; Demjaha, Arsime

2013-03-01

In recent years, psychopharmacological intervention in prodromal psychosis, also known as the ultra-high risk (UHR) mental state for psychosis, has attracted much attention. Whilst it has been shown that antipsychotic use in UHR individuals may be effective in potentially delaying or even averting progression to frank psychosis, their use in subjects that do not necessarily convert to psychosis has raised considerable ethical concerns because of their adverse effects. Recent treatment guidelines for patients at UHR for psychosis recommend the use of antipsychotics only in exceptional conditions and with great precautions. To date only a few studies have investigated the use of antipsychotic medications in UHR patients and the potential benefits and risks related to their use in prodromal psychosis remain unclear. We review here all published studies that included UHR patients treated with antipsychotics, regardless of study design. These studies were all of second-generation antipsychotics, given that first-generation antipsychotics cannot be recommended because of their adverse drug reactions. We specifically examine the available descriptions of adverse reactions of the individual antipsychotic medication in each study and discuss the potential effects of various demographic and clinical factors that may impact on safety issues of pharmacological interventions in UHR patients. Clinical trials to date investigating potential benefits of antipsychotic treatments in preventing transition to psychosis were of relatively short duration and have involved a small number of patients. Whilst it appears that pharmacological intervention at this stage may be effective in both reducing the psychopathology and decreasing transition rates, and is potentially safe, in the absence of sufficient evidence-based knowledge to guide treatment, definitive clinical recommendations and guidelines cannot be derived. Certain adverse events take time to develop, such as metabolic syndrome

Ultra-high resolution optical coherence tomography for encapsulation quality inspection

KAUST Repository

Czajkowski, Jakub

2011-08-28

We present the application of ultra-high resolution optical coherence tomography (UHR-OCT) in evaluation of thin, protective films used in printed electronics. Two types of sample were investigated: microscopy glass and organic field effect transistor (OFET) structure. Samples were coated with thin (1-3 μm) layer of parylene C polymer. Measurements were done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti: sapphire femtosecond laser, photonic crystal fibre and modified, free-space Michelson interferometer. Submicron resolution offered by the UHR-OCT system applied in the study enables registration of both interfaces of the thin encapsulation layer. Complete, volumetric characterisation of protective layers is presented, demonstrating possibility to use OCT for encapsulation quality inspection. © Springer-Verlag 2011.

Associations of infant nutrition with insulin resistance measures in early adulthood: evidence from the Barry-Caerphilly Growth (BCG study.

Directory of Open Access Journals (Sweden)

Dylan M Williams

Full Text Available Previous studies suggest that over-nutrition in early infancy may programme long-term susceptibility to insulin resistance.To assess the association of breast milk and quantity of infant formula and cows' milk intake during infancy with insulin resistance measures in early adulthood.Long-term follow-up of the Barry Caerphilly Growth cohort, into which mothers and their offspring had originally been randomly assigned, between 1972-1974, to receive milk supplementation or not. Participants were the offspring, aged 23-27 years at follow-up (n = 679. Breastfeeding and formula/cows' milk intake was recorded prospectively by nurses. The main outcomes were insulin sensitivity (ISI(0 and insulin secretion (CIR(30.573 (84% individuals had valid glucose and insulin results and complete covariate information. There was little evidence of associations of breastfeeding versus any formula/cows' milk feeding or of increasing quartiles of formula/cows' milk consumption during infancy (<3 months with any outcome measure in young adulthood. In fully adjusted models, the differences in outcomes between breastfeeding versus formula/cows' milk feeding at 3 months were: fasting glucose (-0.07 mmol/l; 95% CI: -0.19, 0.05; fasting insulin (8.0%; -8.7, 27.6; ISI(0 (-6.1%; -11.3, 12.1 and CIR(30 (3.8%; -19.0, 32.8. There was also little evidence that increasing intakes of formula/cows' milk at 3 months were associated with fasting glucose (increase per quartile of formula/cows' milk intake = 0.00 mmol/l; -0.03, 0.03; fasting insulin (0.8%; -3.2, 5.1; ISI (0 (-0.9%; -5.1, 3.5 and CIR(30 (-2.6%; -8.4, 3.6.We found no evidence that increasing consumption of formula/cows' milk in early infancy was associated with insulin resistance in young adulthood.

Reduced binding potential of GABA-A/benzodiazepine receptors in individuals at ultra-high risk for psychosis: an [18F]-fluoroflumazenil positron emission tomography study.

Science.gov (United States)

Kang, Jee In; Park, Hae-Jeong; Kim, Se Joo; Kim, Kyung Ran; Lee, Su Young; Lee, Eun; An, Suk Kyoon; Kwon, Jun Soo; Lee, Jong Doo

2014-05-01

Altered transmission of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter, may contribute to the development of schizophrenia. The purpose of the present study was to investigate the presence of GABA-A/benzodiazepine (BZ) receptor binding abnormalities in individuals at ultra-high risk (UHR) for psychosis in comparison with normal controls using [(18)F]-fluoroflumazenil (FFMZ) positron emission tomography (PET). In particular, we set regions of interest in the striatum (caudate, putamen, and nucleus accumbens) and medial temporal area (hippocampus and parahippocampal gyrus). Eleven BZ-naive people at UHR and 15 normal controls underwent PET scanning using [(18)F]-FFMZ to measure GABA-A/BZ receptor binding potential. The regional group differences between UHR individuals and normal controls were analyzed using Statistical Parametric Mapping 8 software. Participants were evaluated using the structured interview for prodromal syndromes and neurocognitive function tasks. People at UHR demonstrated significantly reduced binding potential of GABA-A/BZ receptors in the right caudate. Altered GABAergic transmission and/or the imbalance of inhibitory and excitatory systems in the striatum may be present at the putative prodromal stage and play a pivotal role in the pathophysiology of psychosis.

Cannabis-induced attenuated psychotic symptoms: implications for prognosis in young people at ultra-high risk for psychosis.

Science.gov (United States)

McHugh, M J; McGorry, P D; Yung, A R; Lin, A; Wood, S J; Hartmann, J A; Nelson, B

2017-03-01

Cannabis use shows a robust dose-dependent relationship with psychosis risk among the general population. Despite this, it has been difficult to link cannabis use with risk for transitioning to a psychotic disorder among individuals at ultra-high risk (UHR) for psychosis. The present study examined UHR transition risk as a function of cannabis use characteristics which vary substantially between individuals including age of first use, cannabis abuse severity and a history of cannabis-induced attenuated psychotic symptoms (APS). Participants were 190 UHR individuals (76 males) recruited at entry to treatment between 2000 and 2006. They completed a comprehensive baseline assessment including a survey of cannabis use characteristics during the period of heaviest use. Outcome was transition to a psychotic disorder, with mean time to follow-up of 5.0 years (range 2.4-8.7 years). A history of cannabis abuse was reported in 58% of the sample. Of these, 26% reported a history of cannabis-induced APS. These individuals were 4.90 (95% confidence interval 1.93-12.44) times more likely to transition to a psychotic disorder (p = 0.001). Greater severity of cannabis abuse also predicted transition to psychosis (p = 0.036). However, this effect was mediated by higher abuse severity among individuals with a history of cannabis-induced APS. Findings suggest that cannabis use poses risk in a subpopulation of UHR individuals who manifest cannabis-induced APS. Whether this reflects underlying genetic vulnerability requires further study. Nevertheless, findings reveal an important early marker of risk with potentially significant prognostic utility for UHR individuals.

Mismatch and lexical retrieval gestures are associated with visual information processing, verbal production, and symptomatology in youth at high risk for psychosis.

Science.gov (United States)

Millman, Zachary B; Goss, James; Schiffman, Jason; Mejias, Johana; Gupta, Tina; Mittal, Vijay A

2014-09-01

Gesture is integrally linked with language and cognitive systems, and recent years have seen a growing attention to these movements in patients with schizophrenia. To date, however, there have been no investigations of gesture in youth at ultra high risk (UHR) for psychosis. Examining gesture in UHR individuals may help to elucidate other widely recognized communicative and cognitive deficits in this population and yield new clues for treatment development. In this study, mismatch (indicating semantic incongruency between the content of speech and a given gesture) and retrieval (used during pauses in speech while a person appears to be searching for a word or idea) gestures were evaluated in 42 UHR individuals and 36 matched healthy controls. Cognitive functions relevant to gesture production (i.e., speed of visual information processing and verbal production) as well as positive and negative symptomatologies were assessed. Although the overall frequency of cases exhibiting these behaviors was low, UHR individuals produced substantially more mismatch and retrieval gestures than controls. The UHR group also exhibited significantly poorer verbal production performance when compared with controls. In the patient group, mismatch gestures were associated with poorer visual processing speed and elevated negative symptoms, while retrieval gestures were associated with higher speed of visual information-processing and verbal production, but not symptoms. Taken together these findings indicate that gesture abnormalities are present in individuals at high risk for psychosis. While mismatch gestures may be closely related to disease processes, retrieval gestures may be employed as a compensatory mechanism. Copyright © 2014 Elsevier B.V. All rights reserved.

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis.

Science.gov (United States)

Padula, Maria Carmela; Schaer, Marie; Armando, Marco; Sandini, Corrado; Zöller, Daniela; Scariati, Elisa; Schneider, Maude; Eliez, Stephan

2018-01-17

Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neural biomarkers do not yet exist. However, a number of investigations indicated an association between abnormalities in cortical morphology and higher symptoms severities in patients with 22q11DS. Nevertheless, few studies included homogeneous groups of patients differing in their psychotic symptoms profile. In this study, we included 22 patients meeting the criteria for an ultra-high-risk (UHR) psychotic state and 22 age-, gender- and IQ-matched non-UHR patients. Measures of cortical morphology, including cortical thickness, volume, surface area and gyrification, were compared between the two groups using mass-univariate and multivariate comparisons. Furthermore, the development of these measures was tested in the two groups using a mixed-model approach. Our results showed differences in cortical volume and surface area in UHR patients compared with non-UHR. In particular, we found a positive association between surface area and the rate of change of global functioning, suggesting that higher surface area is predictive of improved functioning with age. We also observed accelerated cortical thinning during adolescence in UHR patients with 22q11DS. These results, although preliminary, suggest that alterations in cortical volume and surface area as well as altered development of cortical thickness may be associated to a greater probability to develop psychosis in 22q11DS.

NEURAPRO-E study protocol: a multicentre randomized controlled trial of omega-3 fatty acids and cognitive-behavioural case management for patients at ultra high risk of schizophrenia and other psychotic disorders.

Science.gov (United States)

Markulev, Connie; McGorry, Patrick D; Nelson, Barnaby; Yuen, Hok Pan; Schaefer, Miriam; Yung, Alison R; Thompson, Andrew; Berger, Gregor; Mossaheb, Nilufar; Schlögelhofer, Monika; Smesny, Stefan; de Haan, Lieuwe; Riecher-Rössler, Anita; Nordentoft, Merete; Chen, Eric Yu Hai; Verma, Swapna; Hickie, Ian; Amminger, G Paul

2017-10-01

Recent research has indicated that preventative intervention is likely to benefit patients 'at-risk' for psychosis, both in terms of symptom reduction and delay or prevention of onset of threshold psychotic disorder. The strong preliminary results for the effectiveness of omega-3 polyunsaturated fatty acids (PUFAs), coupled with the falling transition rate in ultra high-risk (UHR) samples, mean that further study of such benign, potentially neuroprotective interventions is clinically and ethically required. Employing a multicentre approach, enabling a large sample size, this study will provide important information with regard to the use of omega-3 PUFAs in the UHR group. This trial is a 6-month, double-blind, randomized placebo-controlled trial of 1.4 g day -1 omega-3 PUFAs in UHR patients aged between 13 and 40 years. The primary hypothesis is that UHR patients receiving omega-3 PUFAs plus cognitive-behavioural case management (CBCM) will be less likely to transition to psychosis over a 6-month period compared to treatment with placebo plus CBCM. Secondary outcomes will examine symptomatic and functional changes, as well as examine if candidate risk factors predict response to omega-3 PUFA treatment in the UHR group. This is the protocol of the NeuraproE study. Utilizing a large sample, results from this study will be important in informing indicated prevention strategies for schizophrenia and other psychotic disorders, which may be the strongest avenue for reducing the burden, stigmatization, disability and economic consequences of these disorders. © 2015 Wiley Publishing Asia Pty Ltd.

Cryospheric Change Impacts on Alpine Hydrology: Combining Model With Observations in the Upper Reaches of Hei River, China

Science.gov (United States)

Li, X.; Chen, R.; Wang, G.; Liu, J.; Yang, Y.; Han, C.; Song, Y.; Liu, Z.; Kang, E.

2017-12-01

Cryospheric change impacts largely on alpine hydrology but they are still unclear owing to rare observations and suitable models in the Western Cold Regions of China (WCRC), where many large rivers including almost inland rivers originate and some of them flow to adjacent countries. The upstream of the inland river provides nearly almost water resources to the arid mid-downstream areas, such as the Hei River. Based on the long term field observation in WCRC, a Cryospheric Basin Hydrological Model (CBHM) was created to evaluate the cryospheric impacts on streamflow in the upper reaches of Hei river (UHR), and relationships between Cryosphere and streamflow were further discussed by using measured data. The NorESM1-ME were chosen to project future streamflow under scenarios RCP2.6, RCP4.5 and RCP8.5. The monthly basin runoff in UHR was simulated with a coefficient of efficiency about 0.93 and 0.94, and a mass balance error about 2.5% and -0.2% during the calibration period from 1960 to 1990 and validation period from 1991 to 2013, respectively. The CBHM results were then well validated by measured evapotranspiration (ET), soil temperature, glacier area, water balance of land covers etc. in UHR. It found that the moraine-talus region was the major runoff contribution (60.5%) area though its area proportion was only about 20%, whereas the total runoff contribution of meadow and grassland was only about 27% but their area ratio was about 70% in UHR. Glacier and snow cover contributed 3.5% and 25.4% fresh water in average to streamflow during 1960 to 2013 in HUR. Owing to the increased air temperature (2.9 oC/54a) and precipitation (69.2 mm/54a) in the past 54 years, glacial and snow melting runoff increased 9.8% and 12.1%, respectively. The air temperature rise decreased and brought forward the snowmelt flood peak, and increased the winter flow due to permafrost degradation in UHR. Glaciers would disappear in the near future owing to its small size and increasing air

ACHP | News | ACHP Issue Spotlight: Transmission Lines in the West

Science.gov (United States)

experience, creativity, and leadership when they were greatly needed. Donaldson was accompanied by his wife Leadership Chairman Wayne Donaldson Receives AIA Award for Leadership ACHP Chairman Milford Wayne Donaldson recognition of leadership provided by Milford Wayne Donaldson, FAIA, in historic preservation at the national

Physical activity level and medial temporal health in youth at ultra high-risk for psychosis.

Science.gov (United States)

Mittal, Vijay A; Gupta, Tina; Orr, Joseph M; Pelletier-Baldelli, Andrea; Dean, Derek J; Lunsford-Avery, Jessica R; Smith, Ashley K; Robustelli, Briana L; Leopold, Daniel R; Millman, Zachary B

2013-11-01

A growing body of evidence suggests that moderate to vigorous activity levels can affect quality of life, cognition, and brain structure in patients diagnosed with schizophrenia. However, physical activity has not been systematically studied during the period immediately preceding the onset of psychosis. Given reports of exercise-based neurogenesis in schizophrenia, understanding naturalistic physical activity levels in the prodrome may provide valuable information for early intervention efforts. The present study examined 29 ultra high-risk (UHR) and 27 matched controls to determine relationships between physical activity level, brain structure (hippocampus and parahippocampal gyrus), and symptoms. Participants were assessed with actigraphy for a 5-day period, MRI, and structured clinical interviews. UHR participants showed a greater percentage of time in sedentary behavior while healthy controls spent more time engaged in light to vigorous activity. There was a strong trend to suggest the UHR group showed less total physical activity. The UHR group exhibited smaller medial temporal volumes when compared with healthy controls. Total level of physical activity in the UHR group was moderately correlated with parahippocampal gyri bilaterally (right: r = .44, left: r = .55) and with occupational functioning (r = -.36; of negative symptom domain), but not positive symptomatology. Results suggest that inactivity is associated with medial temporal lobe health. Future studies are needed to determine if symptoms are driving inactivity, which in turn may be affecting the health of the parahippocampal structure and progression of illness. Although causality cannot be determined from the present design, these findings hold important implications for etiological conceptions and suggest promise for an experimental trial. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Examining the physical health and lifestyle of young people at ultra-high risk for psychosis: A qualitative study involving service users, parents and clinicians.

Science.gov (United States)

Carney, Rebekah; Cotter, Jack; Bradshaw, Tim; Yung, Alison R

2017-09-01

Emerging evidence suggests young people at ultra-high risk for psychosis (UHR) are also at-risk for poor physical health, and display high rates of modifiable cardiometabolic risk factors. However, before we can develop effective interventions there is a need to understand factors affecting lifestyle choices in the UHR group. We conducted semi-structured qualitative interviews with 20 UHR individuals (50% male; mean age 21.7), 5 parents (4 mothers, 1 father), and 6 clinicians from early intervention services in the Northwest of England to identify barriers and facilitators to living a healthy lifestyle, including achieving regular exercise, eating well and refraining from excessive substance use. Thematic analysis revealed the main barriers to living a healthy lifestyle related to psychiatric symptoms, beliefs about self, social withdrawal and practical considerations such as accessibility and cost. Provision of social support and promoting autonomy emerged as the two main themes which would facilitate a healthy lifestyle. Promoting physical health in people with emerging symptoms of psychosis is an important, yet neglected area of mental health practice and warrants further investigation. UHR individuals experience numerous barriers to living a healthy lifestyle, and interventions should focus primarily on targeting autonomous motivation and providing social support to facilitate this change. Copyright © 2017. Published by Elsevier B.V.

Impaired Social and Role Function in Ultra-High Risk for Psychosis and First-Episode Schizophrenia: Its Relations with Negative Symptoms.

Science.gov (United States)

Lee, So Jung; Kim, Kyung Ran; Lee, Su Young; An, Suk Kyoon

2017-09-01

Psychosocial dysfunction was a nettlesome problem of schizophrenia even in their prodromal phase as well as in their first-episode. In addition, its relations with psychopathology were not determined. The aim of the present study was to examine whether the social and role function impairment was found in ultra-high risk for psychosis (UHR) individuals as well as first-episode schizophrenia patients and to explore its relations with psychopathology. Thirty-seven normal controls, 63 UHR participants and 28 young, first-episode schizophrenia patients were recruited. Psychosocial functioning was examined by using Global function: Social and Role scale. Psychopathologies of positive, negative and depressive symptom were also measured. Social and role functioning in UHR were compromised at the equivalent level of those of first-episode schizophrenia patients. Multiple linear regression analysis revealed that social and role dysfunction was associated with negative symptoms in each UHR and first-episode schizophrenia group. These findings suggest that the significant impairment of social and role function may be appeared before the active psychosis onset at the level of extent to those of first-episode schizophrenia patients. The psychosocial intervention strategy especially targeting the negative symptoms should be developed and provided to individuals from their prepsychotic stage of schizophrenia.

Psychopathology and social functioning of 42 subjects from a Danish ultra high-risk cohort

DEFF Research Database (Denmark)

Madsen, Helle Karkov; Nordholm, Dorte; Krakauer, Kristine

2017-01-01

history of psychiatric disorders. Results: All UHR subjects met the criteria of at least 1 axis I diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) and met on average four diagnoses (both axis I and II), mostly within the areas of depression, anxiety......Aim: To make a thorough characterization of the co-morbidity, psychopathology and demographics in the first Danish ultra high-risk (UHR) sample. Method: Forty-two UHR subjects went through comprehensive interviews assessing their psychopathology, psychiatric disorders, substance use and family...... and substance abuse. A total of 48% had schizotypal personality disorder and 19% had borderline personality disorder. Level of functioning was low with a mean score on the Social and Occupational Functioning Assessment Scale corresponding to "major impairment in several areas," and mean scores in the Global...

Various / Barry Witherden

Index Scriptorium Estoniae

Witherden, Barry

1996-01-01

Uuest heliplaadist "Various. John Keys (organ), Andrew Angus (bass). Vasari Singers / Jeremy Backhouse". EMI Eminence 7243 5 65 903 2. 74:09 DDD. Plaadil ka A. Pärdi "Summa", "The Beautitudes", "Seven Magnificat Antiphons"

Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomography

International Nuclear Information System (INIS)

Unterhuber, A; Povazay, B; Bizheva, K; Hermann, B; Sattmann, H; Stingl, A; Le, T; Seefeld, M; Menzel, R; Preusser, M; Budka, H; Schubert, Ch; Reitsamer, H; Ahnelt, P K; Morgan, J E; Cowey, A; Drexler, W

2004-01-01

Novel ultra-broad bandwidth light sources enabling unprecedented sub-2 μm axial resolution over the 400 nm-1700 nm wavelength range have been developed and evaluated with respect to their feasibility for clinical ultrahigh resolution optical coherence tomography (UHR OCT) applications. The state-of-the-art light sources described here include a compact Kerr lens mode locked Ti:sapphire laser (λ c = 785 nm, Δλ = 260 nm, P out = 50 mW) and different nonlinear fibre-based light sources with spectral bandwidths (at full width at half maximum) up to 350 nm at λ c = 1130 nm and 470 nm at λ c = 1375 nm. In vitro UHR OCT imaging is demonstrated at multiple wavelengths in human cancer cells, animal ganglion cells as well as in neuropathologic and ophthalmic biopsies in order to compare and optimize UHR OCT image contrast, resolution and penetration depth

Non-destructive testing of layer-to-layer fusion of a 3D print using ultrahigh resolution optical coherence tomography

DEFF Research Database (Denmark)

Israelsen, Niels Møller; Maria, Michael; Feuchter, Thomas

2017-01-01

Within the last decade, 3D printing has moved from a costly approach of building mechanical items to the present state-of-the-art phase where access to 3D printers is now common, both in industry and in private places. The plastic printers are the most common type of 3D printers providing prints...... on volume imaging of a 3D printed block made with 100% PLA fill. By employing ultrahigh resolution OCT (UHR-OCT) we show that some parts of the PLA volume reveal highly scattering interfaces which likely correspond to transitions from one layer to another. In doing so, we document that UHR-OCT can act...... as a powerful tool that can be used in detecting fractures between layers stemming from insufficient fusion between printed structure layers. UHR-OCT can therefore serve as an useful assessment method of quality of 3D prints....

Do cognitive schema mediate the association between childhood trauma and being at ultra-high risk for psychosis?

Science.gov (United States)

Appiah-Kusi, E; Fisher, H L; Petros, N; Wilson, R; Mondelli, V; Garety, P A; Mcguire, P; Bhattacharyya, S

2017-05-01

Exposure to childhood trauma has been associated with psychotic symptoms, being at ultra-high risk for psychosis (UHR), and psychotic disorders such as schizophrenia. Negative self-beliefs have been shown to partially mediate the relationship between childhood trauma and paranoia and have been shown to be characteristic of patients with psychosis. However, whether the association between childhood trauma and being at high risk of developing psychosis (e.g., UHR) and paranoia symptoms is mediated by altered cognitive schema is unknown and warrants investigation to inform preventive interventions. Data was collected on 30 UHR patients from Outreach and Support in South London about exposure to childhood trauma, cognitive schema, paranoia and cannabis use. Relative to healthy controls (n = 38), UHR patients were significantly more likely to report exposure to various types of childhood trauma (emotional and sexual abuse, and emotional and physical neglect), had more negative schema and less positive schema about themselves and others, and were more likely to use cannabis more than once a month. Emotional neglect was found to be significantly associated with UHR status even after controlling for the effects of previous exposure to cannabis use (b = 0.262, 95% CI: 0.115-0.408), and this association was partially mediated by negative self-schema (b = 0.045, 95% CI: 0.004-0.159). Similarly, emotional neglect was significantly associated with paranoia (b = 1.354, 95% CI: 0.246-2.462), and this association was partially mediated by negative self-schema (b = 0.988, 95% CI: 0.323-1.895). These findings provide preliminary evidence about the cognitive mechanisms that may underlie the association between childhood trauma and later risk for psychosis. Copyright © 2017 Elsevier Ltd. All rights reserved.

Validation of the Voice of America Coverage Analysis Program (VOACAP)

Science.gov (United States)

2013-02-01

34 ======================================================================= ================== Points of contact: Wayne Patterson 619-553-1423 wayne.patterson@navy.mil (Areps, Enviro ) 29 Amalia Barrios 619

Motion energy analysis reveals altered body movement in youth at risk for psychosis.

Science.gov (United States)

Dean, Derek J; Samson, Alayna T; Newberry, Raeana; Mittal, Vijay A

2017-06-03

Growing evidence suggests that movement abnormalities occur prior to the onset of psychosis. Innovations in technology and software provide the opportunity for a fine-tuned and sensitive measurement of observable behavior that may be particularly useful to detecting the subtle movement aberrations present during the prodromal period. In the present study, 54 youth at ultrahigh risk (UHR) for psychosis and 62 healthy controls participated in structured clinical interviews to assess for an UHR syndrome. The initial 15min of the baseline clinical interview was assessed using Motion Energy Analysis (MEA) providing frame-by-frame measures of total movement, amplitude, speed, and variability of both head and body movement separately. Result showed region-specific group differences such that there were no differences in head movement but significant differences in body movement. Specifically, the UHR group showed greater total body movement and speed of body movements, and lower variation in body movement compared to healthy controls. However, there were no significant associations with positive, negative or disorganized symptom domains. This study represents an innovative perspective on gross motor function in the UHR group. Importantly, the automated approach used in this study provides a sensitive and objective measure of body movement abnormalities, potentially guiding novel assessment and prevention of symptom development in those at risk for psychosis. Copyright © 2017. Published by Elsevier B.V.

Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis.

Science.gov (United States)

Rietdijk, Judith; Ising, Helga K; Dragt, Sara; Klaassen, Rianne; Nieman, Dorien; Wunderink, Lex; Cuijpers, Pim; Linszen, Don; van der Gaag, Mark

2013-10-30

Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression are highly prevalent in an UHR population, particularly among women. From February 2008 to February 2010 baseline data were collected from help-seeking subjects (14-35 years) who were included in the Dutch Early Detection and Intervention Evaluation (EDIE-NL) trial. Two recruiting strategies were used: a two-stage screening strategy in a population of consecutive help-seeking and distressed subjects of secondary mental health services, and a referral strategy. This study included 201 patients with a mean age of 22.7 years. Of these, 102 (51%) were female, 58% of the patients met the criteria for clinical depression on the Beck Depression Inventory and 42% met the criteria for clinical social phobia on the Social Interaction Anxiety Scale. Women showed more depression and social anxiety than men. The results support the hypothesis that UHR is associated with depression and social anxiety, particularly in women. Screening a help-seeking population with depression and anxiety may be effective in detecting patients at UHR for developing psychosis. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Plasma heating due to X-B mode conversion in a cylindrical ECR plasma system

Energy Technology Data Exchange (ETDEWEB)

Yadav, V.K.; Bora, D. [Institute for Plasma Research, Bhat, Gandhinagar, Gujarat (India)

2004-07-01

Extra Ordinary (X) mode conversion to Bernstein wave near Upper Hybrid Resonance (UHR) layer plays an important role in plasma heating through cyclotron resonance. Wave generation at UHR and parametric decay at high power has been observed during Electron Cyclotron Resonance (ECR) heating experiments in toroidal magnetic fusion devices. A small linear system with ECR and UHR layer within the system has been used to conduct experiments on X-B conversion and parametric decay process as a function of system parameters. Direct probing in situ is conducted and plasma heating is evidenced by soft x-ray emission measurement. Experiments are performed with hydrogen plasma produced with 160-800 W microwave power at 2.45 GHz of operating frequency at 10{sup -3} mbar pressure. The axial magnetic field required for ECR is such that the resonant surface (B = 875 G) is situated at the geometrical axis of the plasma system. Experimental results will be presented in the paper. (authors)

Reduced γ-Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk

Directory of Open Access Journals (Sweden)

Junjie Wang

2016-01-01

Full Text Available Altered γ-aminobutyric acid (GABA, glutamate (Glu levels, and an imbalance between GABAergic and glutamatergic neurotransmissions have been involved in the pathophysiology of schizophrenia. However, it remains unclear how these abnormalities impact the onset and course of psychosis. In the present study, 21 drug-naïve subjects at ultrahigh risk for psychosis (UHR, 16 drug-naïve patients with first-episode schizophrenia (FES, and 23 healthy controls (HC were enrolled. In vivo GABA and glutamate+glutamine (Glx levels in the medial prefrontal cortex were measured using proton magnetic resonance spectroscopy. Medial prefrontal GABA and Glx levels in FES patients were significantly lower than those in HC and UHR, respectively. GABA and Glx levels in UHR were comparable with those in HC. In each group, there was a positive correlation between GABA and Glx levels. Reduced medial prefrontal GABA and Glx levels thus may play an important role in the early stages of schizophrenia.

Reduced γ-Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk.

Science.gov (United States)

Wang, Junjie; Tang, Yingying; Zhang, Tianhong; Cui, Huiru; Xu, Lihua; Zeng, Botao; Li, Yu; Li, Gaiying; Li, Chunbo; Liu, Hui; Lu, Zheng; Zhang, Jianye; Wang, Jijun

2016-01-01

Altered γ -aminobutyric acid (GABA), glutamate (Glu) levels, and an imbalance between GABAergic and glutamatergic neurotransmissions have been involved in the pathophysiology of schizophrenia. However, it remains unclear how these abnormalities impact the onset and course of psychosis. In the present study, 21 drug-naïve subjects at ultrahigh risk for psychosis (UHR), 16 drug-naïve patients with first-episode schizophrenia (FES), and 23 healthy controls (HC) were enrolled. In vivo GABA and glutamate+glutamine (Glx) levels in the medial prefrontal cortex were measured using proton magnetic resonance spectroscopy. Medial prefrontal GABA and Glx levels in FES patients were significantly lower than those in HC and UHR, respectively. GABA and Glx levels in UHR were comparable with those in HC. In each group, there was a positive correlation between GABA and Glx levels. Reduced medial prefrontal GABA and Glx levels thus may play an important role in the early stages of schizophrenia.

La construction de l’espace touristique de la Grande Barrière de Corail : entre protection de l’environnement et modifications de l’accessibilité au récif

Directory of Open Access Journals (Sweden)

Luc Vacher

2008-09-01

Full Text Available La Grande Barrière de Corail s’étend sur 2000 kilomètres le long de la côte orientale de l’État du Queensland en Australie. Chaque année, le “ Great Barrier Reef Marine Park ”, le plus grand parc marin du monde établi en 1975, compte plus de 1,8 millions d’entrées. Depuis 1981, cet ensemble d’îles et de récifs est aussi inscrit sur la Liste du Patrimoine mondial de l’UNESCO. La mise en tourisme de la région, qui s’est faite progressivement autour de l’exploitation de cette attraction, n’a pas été uniforme.  Ce texte a pour objectif d’aider à comprendre la différentiation spatiale du développement touristique dans la région. Une analyse des changements dans la perception du récif montre que l’importance de la préoccupation environnementale est ancienne dans la gestion de cet ensemble, mais qu’elle a évolué. L’augmentation de la fréquentation de la Grande Barrière par les touristes est ensuite replacée dans le contexte de la croissance du tourisme australien. Enfin l’importance des conditions techniques et du cadre légal de l’accès aux récifs sont envisagés pour expliquer la polarisation actuelle du développement autour des zones de Cairns/Port Douglas et des îles Whitsunday.The Great Barrier Reef extends over 2000 kilometres along the eastern coast of Queensland in Australia. Every year, the "Great Barrier Reef Marine Park", the biggest marine park in the world established in 1975, counts more than 1.8 million entries. Since 1981, this group of islands and reefs is also registered on the UNESCO World Heritage List. The touristification of the region, which was gradually achieved around the operation of this attraction, was not uniform. This text has for objective to help to understand the spatial differentiation of the tourist development in the area. An analysis of the changes in the perception of the reef show that the importance of the environmental concern  is well established

75 FR 77638 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

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2010-12-13

.... 20110196 G Barry Diller. G Barry Diller. G IAC/InterActiveCorp. 20110197 G Barry Diller. G Liberty Media... Machine, Inc. d/b/a Living Social G Hungry Machine, Inc. 02-DEC-10 20110212 G Right Choice Credit Union, G.... 20110185 G Excellere Partners. G The SV Partners Limited Partnership. G AxelaCare Health Solutions, LLC...

Dopamine in high-risk populations: A comparison of subjects with 22q11.2 deletion syndrome and subjects at ultra high-risk for psychosis.

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Vingerhoets, Claudia; Bloemen, Oswald J N; Boot, Erik; Bakker, Geor; de Koning, Mariken B; da Silva Alves, Fabiana; Booij, Jan; van Amelsvoort, Thérèse A M J

2018-02-28

Striatal dopamine (DA) dysfunction has been consistently reported in psychotic disorders. Differences and similarities in the pathogenesis between populations at clinical and genetic risk for developing psychosis are yet to be established. Here we explored markers of dopamine (DA) function in subjects meeting clinically ultra-high risk criteria for psychosis (UHR) and in subjects with 22q11.2 deletion syndrome (22q11DS), a genetic condition associated with significant risk for developing psychotic disorders. Single Photon Emission Computed Tomography (SPECT) with 123 I-labelled iodobenzamide ([ 123 I]IBZM) was used to measure striatal DA D 2/3 receptor binding potential (D 2 R BP ND ). Also, peripheral DAergic markers were assessed in serum and urine (plasma prolactin (pPRL), plasma homovanillic acid (pHVA) and urine DA(uDA)). No significant difference in striatal D 2 R BP ND was found between UHR and 22q11DS subjects. Compared to UHR subjects, pPRL and pHVA were lower and uDA levels were higher in the 22q11DS subjects. However, after correcting for age and gender, only pPRL as significantly lower in the 22q11DS patients. These results may suggest that there are differences in DAergic markers between subjects with UHR and with 22q11DS that may reflect differences in the pathways to psychosis. However, bigger samples are needed to replicate these findings. Copyright © 2017 Elsevier B.V. All rights reserved.

Assessment of independent risk factors of conversion into psychosis in the ultra-high risk state group of patients

Directory of Open Access Journals (Sweden)

Marta Gawłowska

2010-12-01

Full Text Available Background: The aim of this study was the independent psychosis risk factors assessment in a group of subjects fulfilling the criteria of at risk mental state, under specialist outpatient psychiatric care. Participants: Seventy-one patients – 33 women and 38 men, were involved into this study, aged on average 17.34, all under psychiatric care. The patients were recruited into the study in the sequence of their outpatient clinic admission. The criterion to be included into the study was the diagnosis of ultra-high risk state (UHRS – defined according to the Australian research group principles. Subsequently, the patients were divided into subgroups according to the clinical features of their mental state. Method: The author’s demographic questionnaire was applied in the study. Information regarding the family history of psychosis was obtained from patients and/or their relatives or carers. The patients’ mental state was assessed monthly – according to the presence of psychotic symptoms, change of their incidence and duration, presence of depressive symptoms or aggressive behaviour (measured by a three-level scale. On the basis of the obtained information, we evaluated: 1 conversion into psychosis time – measured from diagnosing of UHRS to the development of full-symptom psychosis, 2 therapeutic methods used (psychotherapy, pharmacotherapy or both, 3 use of psychoactive substances after being diagnosed with UHRS, 4 presence of serious life stressors (the patients’ subjective estimation – during the six-month period preceding the conversion into psychosis. Results: 1 In the UHRS group of patients, staying under professional outpatient psychiatric care, the use of marijuana was an independent risk factor of conversion into psychosis. 2 In the investigated group of patients with at risk mental state we did not find any correlation between modulating factors (including: therapeutic methods used, depressive symptoms, aggression or

Efficacité d'un exutoire de dévalaison et d'une barrière acoustique pour les smolts de saumon atlantique (Salmo salar L. à l'aménagement hydroélectrique de St. Cricq sur le gave d'Ossau.

Directory of Open Access Journals (Sweden)

TRAVADE F.

1999-04-01

Full Text Available Une expérimentation a été conduite en 1996 au niveau de l'aménagement hydroélectrique de St. Cricq (gave d'Ossau dans le but de tester deux dispositifs de dévalaison destinés à éviter le passage dans les turbines des smolts de saumon atlantique (Salmo sala L.. Le premier, localisé au barrage, consiste en une barrière acoustique répulsive destinée à détourner les smolts vers un clapet de décharge. Le champ sonore, généré par 16 émetteurs immergés, est dans la gamme de fréquence 100-600 Hz avec un niveau sonore maximal de 120-130 dB. Le deuxième dispositif, localisé à l'usine, consiste en un exutoire de surface situé en rive, à proximité immédiate de la grille de prise d'eau. L'efficacité des deux dispositifs a été évaluée par marquage-recapture et le comportement des smolts a été suivi par radiotélémétrie. Les passages de smolts par le clapet du barrage varient de 20 % à 60 % ; cette efficacité résulte essentiellement du débit élevé transitant par le clapet. Les tests effectués avec et sans barrière acoustique n'ont mis en évidence aucun effet significatif du champ sonore. L'efficacité de l'exutoire du bassin de mise en charge est d'environ 80 %. La faible largeur de la prise d'eau (11 m, le faible espacement des barreaux de la grille de prise d'eau (2,5 cm, les conditions hydrauliques devant la grille qui guident rapidement les poissons vers l'entrée de l'exutoire, et la configuration de l'entrée de l'exutoire qui crée un écoulement à faible gradient de vitesse peuvent expliquer l'efficacité élevée de ce dispositif.

75 FR 4525 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

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2010-01-28

... FURTHER INFORMATION CONTACT: Wayne Bogovich, National Agricultural Engineer, Conservation Engineering... Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural Resources... of the following methods: Mail: Wayne Bogovich, National Agricultural Engineer, Conservation...

76 FR 52635 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

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2011-08-23

... directed to Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department... personal information provided. FOR FURTHER INFORMATION CONTACT: Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural Resources Conservation...

A NSQIP Analysis of MELD and Perioperative Outcomes in General Surgery.

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Zielsdorf, Shannon M; Kubasiak, John C; Janssen, Imke; Myers, Jonathan A; Luu, Minh B

2015-08-01

It is well known that liver disease has an adverse effect on postoperative outcomes. However, what is still unknown is how to appropriately risk stratify this patient population based on the degree of liver failure. Because data are limited, specifically in general surgery practice, we analyzed the model of end-stage liver disease (MELD) in terms of predicting postoperative complications after one of three general surgery operations: inguinal hernia repair (IHR), umbilical hernia repair (UHR), and colon resection (CRXN). National Surgical Quality Improvement Program data on 17,812 total patients undergoing one of three general surgery operations from 2008 to 2012 were analyzed retrospectively. There were 7402 patients undergoing IHR; 5014 patients undergoing UHR; 5396 patients undergoing CRXN. MELD score was calculated using international normalized ratio, total bilirubin, and creatinine. The primary end point was any postoperative complication. The statistical method used was logistic regression. For IHR, UHR, and CRXN, the overall complication rates were 3.4, 6.4, and 45.9 per cent, respectively. The mean MELD scores were 8.6, 8.5, and 8.5, respectively. For every 1-point increase greater than the mean MELD score, there was a 7.8, 13.8, and 11.6 per cent increase in any postoperative complication. The overall 30-day mortality rate was 0.9 per cent. In conclusion, the MELD score continuum adequately predicts patients' increased risk of postoperative complications after IHR, UHR, and CRXN. Therefore, MELD could be used for preoperative risk stratification and guide clinical decision making for general surgery in the cirrhotic patient.

Cerebello-thalamo-cortical networks predict positive symptom progression in individuals at ultra-high risk for psychosis

Directory of Open Access Journals (Sweden)

Jessica A. Bernard

2017-01-01

Full Text Available Prospective longitudinal evaluation of adolescents at ultra-high-risk (UHR for the development of psychosis enables an enriched neurodevelopmental perspective of disease progression in the absence of many of the factors that typically confound research with formally psychotic patients (antipsychotic medications, drug/alcohol dependence. The cerebellum has been linked to cognitive dysfunction and symptom severity in schizophrenia and recent work from our team suggests that it is a promising target for investigation in UHR individuals as well. However, the cerebellum and cerebello-thalamo-cortical networks have not been investigated developmentally or with respect to disease progression in this critical population. Further, to date, the types of longitudinal multimodal connectivity studies that would substantially inform our understanding of this area have not yet been conducted. In the present investigation 26 UHR and 24 healthy control adolescents were administered structured clinical interviews and scanned at baseline and then again at 12-month time points to investigate both functional and structural connectivity development of cerebello-thalamo-cortical networks in conjunction with symptom progression. Our results provide evidence of abnormal functional and structural cerebellar network development in the UHR group. Crucially, we also found that cerebello-thalamo-cortical network development and connectivity at baseline are associated with positive symptom course, suggesting that cerebellar networks may be a biomarker of disease progression. Together, these findings provide support for neurodevelopmental models of psychotic disorders and suggest that the cerebellum and respective networks with the cortex may be especially important for elucidating the pathophysiology of psychosis and highlighting novel treatment targets.

A study on negative and depressive symptom prevalence in individuals at ultra-high risk for psychosis.

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Azar, Marleine; Pruessner, Marita; Baer, Lawrence H; Iyer, Srividya; Malla, Ashok K; Lepage, Martin

2016-09-21

Negative symptoms are known to be present in the prodromal stage of psychotic disorders, yet little is known about their prevalence. Studies examining the presence of negative symptoms in ultra-high risk (UHR) populations have shown some limitations, notably failing to control depression. The objective of this study was to examine the prevalence of negative symptoms in the presence of significant levels of depression and in the absence of such symptoms (primary negative symptoms) over 1 year and to examine differences in negative symptoms in psychosis converters and non-converters. Participants were 123 individuals at UHR for the development of psychosis receiving follow-up for a period of 2 years. Negative symptoms and depression were measured using the Scale for the Assessment of Negative Symptoms and the Montgomery-Asberg Depression Scale at baseline, 6 and 12 months post-admission. At baseline, the prevalence of negative symptoms and primary negative symptoms was 76.4% and 32.7%, respectively. Whereas the prevalence of negative symptoms was significantly decreased at 6 months, the prevalence of primary negative symptoms was similar at all time points. Negative symptoms at baseline were not different between later converters and non-converters to psychosis. Our findings confirm the presence of secondary and primary negative symptoms in individuals at UHR, but suggest a differential trajectory of both measures over time. Future studies should include larger UHR groups and focus on the investigation of intra-individual changes in primary negative symptoms over time and further explore their potential role for psychosis conversion. © 2016 John Wiley & Sons Australia, Ltd.

Stronger default mode network connectivity is associated with poorer clinical insight in youth at ultra high-risk for psychotic disorders.

Science.gov (United States)

Clark, Sarah V; Mittal, Vijay A; Bernard, Jessica A; Ahmadi, Aral; King, Tricia Z; Turner, Jessica A

2018-03-01

Impaired clinical insight (CI) is a common symptom of psychotic disorders and a promising treatment target. However, to date, our understanding of how variability in CI is tied to underlying brain dysfunction in the clinical high-risk period is limited. Developing a stronger conception of this link will be a vital first step for efforts to determine if CI can serve as a useful prognostic indicator. The current study investigated whether variability in CI is related to major brain networks in adolescents and young adults at ultra high-risk (UHR) of developing psychosis. Thirty-five UHR youth were administered structured clinical interviews as well as an assessment for CI and underwent resting-state magnetic resonance imaging scans. Functional connectivity was calculated in the default mode network (DMN) and fronto-parietal network (FPN), two major networks that are dysfunctional in psychosis and are hypothesized to affect insight. Greater DMN connectivity between the posterior cingulate/precuneus and ventromedial prefrontal cortex (DMN) was related to poorer CI (R 2 =0.399). There were no significant relationships between insight and the FPN. This is the first study to relate a major brain network to clinical insight before the onset of psychosis. Findings are consistent with evidence if a hyperconnected DMN in schizophrenia and UHR, and similar to a previous study of insight and connectivity in schizophrenia. Results suggest that a strongly connected DMN may be related to poor self-awareness of subthreshold psychotic symptoms in UHR adolescents and young adults. Copyright © 2017 Elsevier B.V. All rights reserved.

Britid tahavad euroliitu põhjalikult muuta / Erkki Bahovski

Index Scriptorium Estoniae

Bahovski, Erkki, 1970-

2005-01-01

Suurbritannia lükkas Euroopa Liidu eelarvekava tagasi. Riigi konkurentsiminister Barry Gardineri hinnangul tasub põhiseaduse lepingu kriisi ajal alustada arutelu, kuhu liit liigub. Lisa: Barry Gardiner

75 FR 46903 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

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2010-08-04

... following methods: Mail: Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division... CONTACT: Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department of... technical guidance document National Engineering Handbook Series, Part 651, Agricultural Waste Management...

78 FR 79059 - Public Notice for Waiver of Aeronautical Land-Use Assurance

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2013-12-27

..., Irene Porter, Program Manager, 11677 South Wayne Road, Suite 107, Romulus, Michigan 48174 Telephone... Porter, Program Manager, Federal Aviation Administration, Airports District Office, 11677 South Wayne.... FOR FURTHER INFORMATION CONTACT: Irene Porter, Program Manager, Federal Aviation Administration...

Earliness per se QTLs and their interaction with the photoperiod insensitive allele Ppd-D1a in the Cutler × AC Barrie spring wheat population.

Science.gov (United States)

Kamran, A; Iqbal, M; Navabi, A; Randhawa, H; Pozniak, C; Spaner, D

2013-08-01

Earliness per se regulates flowering time independent of environmental signals and helps to fine tune the time of flowering and maturity. In this study, we aimed to map earliness per se quantitative trait loci (QTLs) affecting days to flowering and maturity in a population developed by crossing two spring wheat cultivars, Cutler and AC Barrie. The population of 177 recombinant inbred lines (RILs) was genotyped for a total of 488 SSR and DArT polymorphic markers on all 21 chromosomes. Three QTLs of earliness per se affecting days to flowering and maturity were mapped on chromosomes 1B (QEps.dms-1B1 and QEps.dms-1B2) and 5B (QEps.dms-5B1), in individual environments and when all the environments were combined. A QTL affecting flowering time (QFlt.dms-4A1) was identified on chromosome 4A. Two grain yield QTLs were mapped on chromosome 5B, while one QTL was mapped on chromosome 1D. The population segregated for the photoperiod insensitive gene, Ppd-D1a, and it induced earlier flowering by 0.69 days and maturity by 1.28 days. The photoperiod insensitive allele Ppd-D1a interacted in an additive fashion with QTLs for flowering and maturity times. The earliness per se QTL QFlt.dms-5B.1 inducing earlier flowering could help to elongate grain filling duration for higher grain yield. Hence, chromosome 5B possesses promising genomic regions that may be introgressed for higher grain yield with earlier maturity through marker-assisted selection in bread wheat.

Ten-year audit of clients presenting to a specialised service for young people experiencing or at increased risk for psychosis.

Science.gov (United States)

Conrad, Agatha M; Lewin, Terry J; Sly, Ketrina A; Schall, Ulrich; Halpin, Sean A; Hunter, Mick; Carr, Vaughan J

2014-11-18

Despite strong research interest in psychosis risk identification and the potential for early intervention, few papers have sought to document the implementation and evaluation of specialised psychosis related services. Assessment of Ultra High Risk (UHR) has been given priority, but it is equally as important to identify appropriate comparison groups and other baseline differences. This largely descriptive service evaluation paper focuses on the 'baseline characteristics' of referred clients (i.e., previously assessed characteristics or those identified within the first two months following service presentation). Data are reported from a 10-year layered service audit of all presentations to a 'Psychological Assistance Service' for young people (PAS, Newcastle, Australia). Baseline socio-demographic and clinical characteristics (N =1,997) are described (including clients' psychosis and UHR status, previous service contacts, hospitalisation rates, and diagnostic and comorbidity profiles). Key groups are identified and comparisons made between clients who received ongoing treatment and those who were primarily assessed and referred elsewhere. Clients averaged 19.2 (SD =4.5) years of age and 59% were male. One-tenth of clients (9.6%) were categorised as UHR, among whom there were relatively high rates of attenuated psychotic symptoms (69.1%), comorbid depression (62.3%), anxiety (42.9%), and attentional and related problems (67.5%). Overall, one-fifth (19.8%) experienced a recent psychotic episode, while a further 14.5% were categorised as having an existing psychosis (46.7% with a schizophrenia diagnosis), amongst whom there were relatively high rates of comorbid substance misuse (52.9%), psychosocial (70.2%) and physical health (37.7%) problems. The largest group presenting to PAS were those with non-psychotic disorders (43.7%), who provide a valuable comparison group against which to contrast the health trajectories of those with UHR and recent psychosis. Ongoing

Impaired action self-monitoring and cognitive confidence among ultra-high risk for psychosis and first-episode psychosis patients.

Science.gov (United States)

Gawęda, Ł; Li, E; Lavoie, S; Whitford, T J; Moritz, S; Nelson, B

2018-01-01

Self-monitoring biases and overconfidence in incorrect judgments have been suggested as playing a role in schizophrenia spectrum disorders. Little is known about whether self-monitoring biases may contribute to early risk factors for psychosis. In this study, action self-monitoring (i.e., discrimination between imagined and performed actions) was investigated, along with confidence in judgments among ultra-high risk (UHR) for psychosis individuals and first-episode psychosis (FEP) patients. Thirty-six UHR for psychosis individuals, 25 FEP patients and 33 healthy controls (CON) participated in the study. Participants were assessed with the Action memory task. Simple actions were presented to participants verbally or non-verbally. Some actions were required to be physically performed and others were imagined. Participants were asked whether the action was presented verbally or non-verbally (action presentation type discrimination), and whether the action was performed or imagined (self-monitoring). Confidence self-ratings related to self-monitoring responses were obtained. The analysis of self-monitoring revealed that both UHR and FEP groups misattributed imagined actions as being performed (i.e., self-monitoring errors) significantly more often than the CON group. There were no differences regarding performed actions as being imagined. UHR and FEP groups made their false responses with higher confidence in their judgments than the CON group. There were no group differences regarding discrimination between the types of actions presented (verbal vs non-verbal). A specific type of self-monitoring bias (i.e., misattributing imagined actions with performed actions), accompanied by high confidence in this judgment, may be a risk factor for the subsequent development of a psychotic disorder. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Slit-lamp photography and videography with high magnifications

Science.gov (United States)

Yuan, Jin; Jiang, Hong; Mao, Xinjie; Ke, Bilian; Yan, Wentao; Liu, Che; Cintrón-Colón, Hector R; Perez, Victor L; Wang, Jianhua

2015-01-01

Purpose To demonstrate the use of the slit-lamp photography and videography with extremely high magnifications for visualizing structures of the anterior segment of the eye. Methods A Canon 60D digital camera with Movie Crop Function was adapted into a Nikon FS-2 slit-lamp to capture still images and video clips of the structures of the anterior segment of the eye. Images obtained using the slit-lamp were tested for spatial resolution. The cornea of human eyes was imaged with the slit-lamp and the structures were compared with the pictures captured using the ultra-high resolution optical coherence tomography (UHR-OCT). The central thickness of the corneal epithelium and total cornea was obtained using the slit-lamp and the results were compared with the thickness obtained using UHR-OCT. Results High-quality ocular images and higher spatial resolutions were obtained by using the slit-lamp with extremely high magnifications and Movie Crop Function, rather than the traditional slit-lamp. The structures and characteristics of the cornea, such as the normal epithelium, abnormal epithelium of corneal intraepithelial neoplasia, LASIK interface, and contact lenses, were clearly visualized using this device. These features were confirmed by comparing the obtained images with those acquired using UHR-OCT. Moreover, the tear film debris on the ocular surface and the corneal nerve in the anterior corneal stroma were also visualized. The thicknesses of the corneal epithelium and total cornea were similar to that measured using UHR-OCT (P photography and videography with extremely high magnifications allows better visualization of the anterior segment structures of the eye, especially of the epithelium, when compared with the traditional slit-lamp. PMID:26020484

Astmed ja hüpped / Meelis Friedenthal

Index Scriptorium Estoniae

Friedenthal, Meelis, 1973-

2010-01-01

Dan Gordoni näidend "Vihmamees" (Rain Man) samanimelise filmi põhjal, filmistsenaariumi autorid Ronald Bass ja Barry Morrow, stsenaariumi aluseks Barry Morrow jutustus, lavastaja Georg Malvius. Esietendus 20. novembril Vanemuise väikeses majas

Wayne—A Simulator for HST   WFC3 IR Grism Spectroscopy

International Nuclear Information System (INIS)

Varley, R.; Tsiaras, A.; Karpouzas, K.

2017-01-01

Wayne is an algorithm that simulates Hubble Space Telescope Wide Field Camera 3 (WFC3) grism spectroscopic frames, including sources of noise and systematics. It can simulate both staring and spatial scan modes, and observations such as the transit and the eclipse of an exoplanet. Unlike many other instrument simulators, the focus of Wayne is on creating frames with realistic systematics in order to test the effectiveness of different data analysis methods in a variety of different scenarios. This approach is critical for method validation and optimizing observing strategies. In this paper we describe the implementation of Wayne for WFC3 in the near-infrared channel with the G102 and G141 grisms. We compare the simulations to real data obtained for the exoplanet HD 209458b, to verify the accuracy of the simulation. The software is now available as open source at https://github.com/ucl-exoplanets/wayne.

Wayne—A Simulator for HST   WFC3 IR Grism Spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Varley, R.; Tsiaras, A. [Department of Physics and Astronomy, University College London, Gower Street, WC1E6BT London (United Kingdom); Karpouzas, K., E-mail: r.varley@ucl.ac.uk [Department of Physics, Section of Astrophysics, Astronomy and Mechanics, Aristotle University of Thessaloniki, 541 24 Thessaloniki (Greece)

2017-07-01

Wayne is an algorithm that simulates Hubble Space Telescope Wide Field Camera 3 (WFC3) grism spectroscopic frames, including sources of noise and systematics. It can simulate both staring and spatial scan modes, and observations such as the transit and the eclipse of an exoplanet. Unlike many other instrument simulators, the focus of Wayne is on creating frames with realistic systematics in order to test the effectiveness of different data analysis methods in a variety of different scenarios. This approach is critical for method validation and optimizing observing strategies. In this paper we describe the implementation of Wayne for WFC3 in the near-infrared channel with the G102 and G141 grisms. We compare the simulations to real data obtained for the exoplanet HD 209458b, to verify the accuracy of the simulation. The software is now available as open source at https://github.com/ucl-exoplanets/wayne.

Plaadid / Priit Hõbemägi

Index Scriptorium Estoniae

Hõbemägi, Priit, 1957-

2006-01-01

Uutest heliplaatidest George Benson "The Essential George Benson", Roy Orbison "The Essential Roy Orbisson", K.D. Lang "Reintaration", Blondie "Greatest Hits", Chris Isaak "Best Of Chris Isaak", Barry Manilov "The Essential Barry Manilow", ABBA "Greatest Hits"

77 FR 50160 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

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2012-08-20

... Lincoln County Coram Hotel, The, 302 California Ave., Libby, 12000593 NEW JERSEY Essex County Woman's Club of Upper Montclair, (Clubhouses of New Jersey Women's Clubs), 200 Cooper Ave., Montclair, 12000594... bounded by Louella Ct., West, & S. Wayne Aves. (Radnor Township), Wayne, 12000607 Lebanon County Mt...

76 FR 68220 - Navistar Truck Development and Technology Center; a Subsidiary of Navistar International...

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2011-11-03

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,151; TA-W-75,151A] Navistar... Renaissance and Alpha Personnel, Inc. Fort Wayne, IN; Navistar Truck Reliability Center, a Subsidiary of... Reliability Center, a Subsidiary of Navistar International Corporation, Truck Division, 3033 Wayne Trace, Fort...

Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis.

Science.gov (United States)

Reniers, Renate L E P; Lin, Ashleigh; Yung, Alison R; Koutsouleris, Nikolaos; Nelson, Barnaby; Cropley, Vanessa L; Velakoulis, Dennis; McGorry, Patrick D; Pantelis, Christos; Wood, Stephen J

2017-03-01

Most individuals at ultra-high risk (UHR) for psychosis do not transition to frank illness. Nevertheless, many have poor clinical outcomes and impaired psychosocial functioning. This study used voxel-based morphometry to investigate if baseline grey and white matter brain densities at identification as UHR were associated with functional outcome at medium- to long-term follow-up. Participants were help-seeking UHR individuals (n = 109, 54M:55F) who underwent magnetic resonance imaging at baseline; functional outcome was assessed an average of 9.2 years later. Primary analysis showed that lower baseline grey matter density, but not white matter density, in bilateral frontal and limbic areas, and left cerebellar declive were associated with poorer functional outcome (Social and Occupational Functioning Assessment Scale [SOFAS]). These findings were independent of transition to psychosis or persistence of the at-risk mental state. Similar regions were significantly associated with lower self-reported levels of social functioning and increased negative symptoms at follow-up. Exploratory analyses showed that lower baseline grey matter densities in middle and inferior frontal gyri were significantly associated with decline in Global Assessment of Functioning (GAF) score over follow-up. There was no association between baseline grey matter density and IQ or positive symptoms at follow-up. The current findings provide novel evidence that those with the poorest functional outcomes have the lowest grey matter densities at identification as UHR, regardless of transition status or persistence of the at-risk mental state. Replication and validation of these findings may allow for early identification of poor functional outcome and targeted interventions. © The Author 2016. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Pituitary gland volume in patients with schizophrenia, subjects at ultra high-risk of developing psychosis and healthy controls: a systematic review and meta-analysis.

Science.gov (United States)

Nordholm, Dorte; Krogh, Jesper; Mondelli, Valeria; Dazzan, Paola; Pariante, Carmine; Nordentoft, Merete

2013-11-01

A larger pituitary size is thought to reflect a greater activation of the hypothalamic-pituitary-adrenal (HPA) axis, which may be related to an increase in the number and size of corticotroph cells. Some studies, but not all, indicate that pituitary volume increases before or at the onset of psychosis. There is a need for at critical appraisal of the literature on this topic accompanied by a meta-analytical evaluation of the data. We included studies comparing the volume of the pituitary gland in healthy controls and patients with schizophrenia, first episode of psychosis (FEP), schizotypal disorder or ultra high-risk (UHR) subjects. We defined three groups of subjects for the analyses: healthy controls; UHR and schizotypal patients; and patients diagnosed with first episode of psychosis, schizophrenia or schizoaffective disorder. Ten studies were included in the meta-analysis. We found a trend of a larger pituitary volume in both UHR subject who had transition to psychosis (p=0.05) and in FEP subjects (p=0.09) compared to healthy controls. There was no difference in pituitary volume between patients with schizophrenia combined with FEP versus healthy controls (p=0.52) or between UHR (with and without transition) and healthy controls (p=0.24). In a regression analysis, we demonstrated that the number of subjects receiving antipsychotics and pituitary volume were positively correlated. As previously reported in other samples, gender also had an impact on pituitary volume with females presenting with a larger mean volume. Results from this meta-analysis suggest that the pituitary gland could be increasing before the onset of psychosis. Both gender and use of antipsychotics have a major impact on the pituitary volume. Copyright © 2013 Elsevier Ltd. All rights reserved.

Prefrontal NAA and Glx Levels in Different Stages of Psychotic Disorders: a 3T 1H-MRS Study.

Science.gov (United States)

Liemburg, Edith; Sibeijn-Kuiper, Anita; Bais, Leonie; Pijnenborg, Gerdina; Knegtering, Henderikus; van der Velde, Jorien; Opmeer, Esther; de Vos, Annerieke; Dlabac-De Lange, Jozarni; Wunderink, Lex; Aleman, André

2016-02-23

H-Magnetic Resonance Spectroscopy ((1)H-MRS) can offer insights in various neuropathologies by measuring metabolite levels in the brain. In the current study we investigated the levels of glutamate + glutamine (Glx, neurotransmitter and precursor) and N-Acetyl Aspartate + glutamic acid (NAA + NAAG; neuronal viability) in the prefrontal cortex of patients with a psychotic disorder and people at Ultra High Risk (UHR) for psychosis. A (1)H-MRS spectrum was acquired in 31 patients with a recent onset psychotic disorder and 60 with a chronic state, 16 UHR patients and 36 healthy controls. Absolute metabolite levels were calculated using LCModel with a reference water peak. Groups were compared while taking into account age and partial volume effects. Moreover, we investigated associations with positive and negative symptoms, duration of illness, and antipsychotic treatment in patients. The most notable finding is that chronicity of schizophrenia was related to decreased levels of Glx and NAA. On the other hand, although on an exploratory note, UHR showed increased levels of prefrontal Glx and NAA levels with increasing age. Our results may indicate an initial Glx and NAA increase and subsequent decrease during illness progression that may be related to the neurotoxic effects of glutamate.

Prevalence and clinical features of Thought-Perception-Sensitivity Symptoms: results from a community survey of Korean high school students.

Science.gov (United States)

Kang, Nam-In; Park, Tae-Won; Yang, Jong-Chul; Oh, Keun-Young; Shim, Shi-Ha; Chung, Young-Chul

2012-08-15

Epidemiologic research indicates that psychosis and depression most frequently develop during adolescence. Hence, an efficient strategy for improving youth mental health would be to focus on detection of early-stage psychosis and depression in adolescence. In this study, 1461 high school students were surveyed using self-report scales. Students who scored equal to or above the cut-off value on any of the scales and who agreed to a further examination proceeded to a second assessment, using the Kiddie Schedule for Affective Disorders and Schizophrenia and Comprehensive Assessment of At-Risk Mental States along with self-reporting scales. The estimated prevalence of adolescents at ultra-high risk (UHR) for psychosis and of depression-spectrum disorders was 1.26 and 3.69% respectively. Compared with the normal group, experiences of bullying, suicidal ideation, and suicide attempts were significantly higher in these two groups; the subjects at UHR for psychosis were found to have significantly lower academic performance and lower ratings on SCRS; and submissive behavior was more prevalent in the depression-spectrum group. Our results reveal several clinical features of adolescents at UHR for psychosis and with depression-spectrum disorder and underscore the importance of accurate assessment of and early appropriate care for these adolescents. Copyright © 2012 Elsevier Ltd. All rights reserved.

FLOODPLAIN, WAYNE COUNTY, MICHIGAN

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the 1-percent-annual-chance...

FLOODPLAIN, WAYNE COUNTY, TENNESSEE

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

HYDROLOGY, WAYNE COUNTY, MISSISSIPPI

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

TERRAIN, WAYNE COUNTY, TENNESSEE

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix N: Data Capture Standards, describes the digital topographic data that was used to create...

New results for virial coefficients of hard spheres in D dimensions

Indian Academy of Sciences (India)

Nathan Clisby1 Barry M McCoy2. ARC Centre of Excellence for Mathematics and Statistics of Complex Systems, 139 Barry Street, The University of Melbourne, Victoria 3010, Australia; C.N. Yang Institute for Theoretical Physics, Stony Brook University, Stony Brook, NY 11794-3840, USA ...

El Raval de Barcelona, un laboratori d'estudis urbans

OpenAIRE

Martínez i Rigol, Sergi; Carreras i Verdaguer, Carles; Frago i Clols, Lluís

2015-01-01

El Raval de Barcelona s'ha convertit en un dels barris més estudiats de la ciutat. En aquest article els autors aprofiten les seves experiències i treballs sobre el barri per reflexionar sobre les eines i els conceptes de la Geografia urbana en l'anàlisi i comprensió de les ciutats contemporànies. De forma quasi cronològica es presenten aquestes reflexions que culminen en un balanç desapassionat de les aportacions que s'han fet des de l'Acadèmia per al coneixement del barri i s...

78 FR 18350 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

Science.gov (United States)

2013-03-26

... Supply Company in Fort Wayne, Indiana, as an addition to the Special Exposure Cohort (SEC) under the... Employees who worked for Joslyn Manufacturing and Supply Company at the covered facility in Fort Wayne, Indiana, from March 1, 1943, through December 31, 1947, for a number of work days aggregating at least 250...

U.S. Department of Energy awards $200 million for next-generation

Science.gov (United States)

, U.S. Congressman Bill Foster, Cray V.P. Marketing & Development Barry Bolding, and Argonne Science and Energy Lynn Orr, U.S. Congressman Bill Foster, Cray V.P. Marketing & Development Barry details on today's announcement. Please monitor Argonne's social media channels at http://www.anl.gov/news

Software Technology for Adaptable Reliable Systems (STARS) Workshop Held at the Naval Research Laboratory, Washington, DC on April 9-12 1985

Science.gov (United States)

1985-01-01

Barrie Baston , MITRE Mike Glasgow, IBM Geoff Mendal, Lockheed LL :8: i::6:: 856 "_--’... ISSUES 1. Define forms and provide rationale for selection: a...George Mendal, Lockheed Missiles and Space Alan Blair, General Dynamics Steve Huseth, Honeywell Miguel Carrio, Teledyne Brown Engineering Barrie Baston

Ciné club et Scuba club

CERN Multimedia

Ciné club et Scuba club

2010-01-01

jeudi 29 avril 2009 à 20 h 30 à l’Amphithéâtre principal du CERN (bâtiment 500) The Cove - La baie de la honte de/by: Louie Psyhoyos (USA, 2009) 92 min. avec/with : Richard O’Barry, Louie Psyhoyos, Simon Hutchins Oscar 2010 “Best Documentary Film at the 82nd Academy Awards” “U.S. Audience Award at the 25th annual Sundance Film Festival in January 2009”   In a sleepy lagoon off the coast of Japan lies a shocking secret that a few desperate men will stop at nothing to keep hidden from the world. In Taiji, Japan, former dolphin trainer Ric O’Barry has come to set things right after a long search for redemption. In the 1960s, it was O’Barry who captured and trained the 5 dolphins who played the title character in the international television sensation “Flipper.” One fateful day, a heartbroken Barry came to realize that these deeply sensitive, highly...

75 FR 43809 - Airworthiness Directives; Piper Aircraft, Inc. PA-28, PA-32, PA-34, and PA-44 Series Airplanes

Science.gov (United States)

2010-07-27

... Aircraft Owners and Pilots Association (AOPA), Barry Rogers, Bruce Chien, and Harry Cook commented that... Absorbed by Piper John Witosky, Thomas McIntosh, Claude Dalrymple, Jr., M. Hefter, and George Haffey..., Barry Rogers, Matt Gunsch, Thomas McIntosh, and four other commenters stated that the FAA needs to...

Evaluation of microfluidic channels with optical coherence tomography

KAUST Repository

Czajkowski, J.; Prykä ri, T.; Alarousu, E.; Lauri, J.; Myllylä , R.

2010-01-01

Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral Drusen in a 31 Year Old Woman.

Science.gov (United States)

de Carlo, Talisa E; Adhi, Mehreen; Lu, Chen D; Duker, Jay S; Fujimoto, James G; Waheed, Nadia K

We report a case of widespread unilateral drusen in a healthy 31 year old Caucasian woman using multi-modal imaging including ultra-high resolution optical coherence tomography (UHR-OCT). Dilated fundus exam showed multiple drusen-like lesions in the posterior pole without heme or fluid. Fundus auto fluorescence demonstrated hyperautofluorescent at the deposits. Fluorescein angiography revealed mild hyperfluorescence and staining of the lesions. Spectral-domain optical coherence tomography (SD-OCT) OS showed accumulations in the temporal macula at Bruch's membrane. UHR-OCT provided improved axial resolution compared to the standard 5 μm on the commercial SD-OCT and confirmed the presence of deposits in Bruch's membrane, consistent with drusen. The retinal layers were draped over the excrescences but did not show any disruption.

Evaluation of microfluidic channels with optical coherence tomography

KAUST Repository

Czajkowski, J.

2010-06-25

Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

Negative symptoms mediate the relationship between neurocognition and function in individuals at ultrahigh risk for psychosis

DEFF Research Database (Denmark)

Glenthøj, L B; Jepsen, Jens Richardt Møllegaard; Hjorthøj, Carsten

2017-01-01

-Risk Social Challenge task and the Scale for the Assessment of Negative Symptoms respectively. Four instruments were used to assess overall functioning, and one instrument assessed quality of life encompassing social functioning. RESULTS: The cross-sectional analyses revealed that neurocognition was related......OBJECTIVE: Neurocognition is known to impact functioning in individuals at ultrahigh risk (UHR) for psychosis, but studies investigating potential mediators of this relationship are scarce. Building on evidence from schizophrenia spectrum disorders, the study tested whether negative symptoms...... and social skills act as mediators between neurocognition and functional outcome in UHR individuals. METHODS: Ultrahigh risk participants (N = 84) underwent neurocognitive testing using the Brief Assessment of Cognition in Schizophrenia. Social skills and negative symptoms were assessed using the High...

Evaluation of microfluidic channels with optical coherence tomography

Science.gov (United States)

Czajkowski, J.; Prykäri, T.; Alarousu, E.; Lauri, J.; Myllylä, R.

2010-11-01

Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

Innovation Engine

Science.gov (United States)

Stuart, Reginald

2012-01-01

This article describes how Wayne State University's TechTown is helping revive Detroit's hard-hit economy. TechTown got its start when then-Wayne State President Irvin Reid and a small group of business leaders in the city and state officials decided Detroit needed to embrace the business incubator idea that had been so successful in other regions…

1829-IJBCS-Article-Barry Mamoudou

African Journals Online (AJOL)

hp

Le Spirulina platensis est une algue utilisée pour ses effets nutritionnel et thérapeutique. De nombreuses études ont montré son intérêt ..... Mesure des cytokines (interleukine-4 (IL-4), l'interféron-γ (IFN-γ) et l'interleukine-2). - Réduction ... avec les métaux et les médicaments pouvant générer des radicaux libres toxiques ...

Türgi valik / Barry Rubin

Index Scriptorium Estoniae

Rubin, Barry

2007-01-01

Õigluse ja Arengu Partei võit Türgi üldvalimistel tähendab, et Kemal Atatürgi 1920. aastatel ilmaliku riigina rajatud Türgi Vabariik on surnud, kuid ei tähenda siiski veel seda, et Türgist saaks islamimaa. Lisa: Presidendiotsing

1827-IJBCS-Article- Barry Mamoudou

African Journals Online (AJOL)

hp

La spiruline est une algue utilisée pour ses effets nutritionnels et thérapeutiques. Cependant son innocuité et ses éventuelles interactions avec les médicaments semblent peu étudier. Le présent travail se propose de résumer les quelques étude et les rapports de pharmacovigilance de la spiruline chez l'homme. La.

Hubungan Kadar FT4 dengan Gejala Klinis yang Terkait Efek Simpatis berdasarkan Indek Wayne pada Nagari Koto Salak Kabupaten Dharmasraya

Directory of Open Access Journals (Sweden)

Nining Kurniawati

2015-05-01

Full Text Available AbstrakPeningkatan aktivitas saraf simpatis dapat terjadi pada keadaan hipertiroid dan sebaliknya pada hipotiroid. Pengukuran kadar hormon tiroid dilakukan dengan mengukur kadar FT4, FT3, TSH, dll. Tujuan penelitian ini adalah untuk mengidentifikasi hubungan kadar FT4 dengan gejala klinis yang terkait efek simpatis di Nagari Koto Salak Kabupaten Dharmasraya. Penelitian ini menggunakan desain penelitian cross sectional study. Hasil penelitian didapatkan subjek dengan peningkatan kadar FT4 12,96%. Subjek dengan gejala klinis palpitasi, penurunan berat badan, nervous, berkeringat lebih dan tremor jari halus dengan persentase berturut-turut adalah 42,59%, 38,89%, 46,30%, 25,93% dan 44,44%. Analisis bivariat dengan menggunakan uji statistik chi-square diperoleh hasil tidak ada hubungan hubungan kadar FT4 dengan 5 gejala klinis yang terkait efek simpatis berdasarkan indeks Wayne (p > 0.05. Penelitian ini masih sederhana dan belum bisa menunjukkan adanya hubungan antara kadar FT4 dengan gejala klinis yang terkait efek simpatis. Sebaiknya untuk penelitian yang akan datang diharapkan dapat memiliki jumlah sampel yang banyak dan cakupan gejala klinis lain yang terlibat dalam aktivitas saraf simpatis yang lebih luas sehingga dapat lebih lengkap dan spesifik.Kata kunci: Kadar FT4, efek simpatis, gejala klinis AbstractIncreased sympathetic nerve activity may occur in the state of hyperthyroidism and conversely in hypothyroidism. Measurement of thyroid hormone levels is done by measuring the levels of FT4, FT3, TSH, etc. The objective of this study was to identify the relation between FT4 levels and the clinical symptoms of sympathetic effects in Nagari Koto Salak Kabupaten Dharmasraya. This research used cross sectional study design. According to the research found that subjects with elevated levels of FT4 12.96%. There are subjects with clinical symptoms of palpitations, weight loss, nervousness, sweating more and fine finger tremor by the following

Adversity in childhood linked to elevated striatal dopamine function in adulthood.

Science.gov (United States)

Egerton, Alice; Valmaggia, Lucia R; Howes, Oliver D; Day, Fern; Chaddock, Christopher A; Allen, Paul; Winton-Brown, Toby T; Bloomfield, Michael A P; Bhattacharyya, Sagnik; Chilcott, Jack; Lappin, Julia M; Murray, Robin M; McGuire, Philip

2016-10-01

Childhood adversity increases the risk of psychosis in adulthood. Theoretical and animal models suggest that this effect may be mediated by increased striatal dopamine neurotransmission. The primary objective of this study was to examine the relationship between adversity in childhood and striatal dopamine function in early adulthood. Secondary objectives were to compare exposure to childhood adversity and striatal dopamine function in young people at ultra high risk (UHR) of psychosis and healthy volunteers. Sixty-seven young adults, comprising 47 individuals at UHR for psychosis and 20 healthy volunteers were recruited from the same geographic area and were matched for age, gender and substance use. Presynaptic dopamine function in the associative striatum was assessed using 18F-DOPA positron emission tomography. Childhood adversity was assessed using the Childhood Experience of Care and Abuse questionnaire. Within the sample as a whole, both severe physical or sexual abuse (T63=2.92; P=0.005), and unstable family arrangements (T57=2.80; P=0.007) in childhood were associated with elevated dopamine function in the associative striatum in adulthood. Comparison of the UHR and volunteer subgroups revealed similar incidence of childhood adverse experiences, and there was no significant group difference in dopamine function. This study provides evidence that childhood adversity is linked to elevated striatal dopamine function in adulthood. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Improved Submariner Eyewear for Routine Wear and Emergency Equipment Use Underway

Science.gov (United States)

2010-01-15

information. 2.0 DESCRIPTION Naval Submarine Medical Research Laboratory (NSMRL) is seeking information from the eyewear industry that will provide...Improved Submariner Eyewear for Routine Wear and Emergency Equipment Use Underway by Alison America, MA Wayne G. Horn, MD...Submariner Eyewear for Routine Wear and Emergency Equipment Use Underway 50818 Alison America, MA Wayne G. Horn, MD Naval Submarine Medical Research

Hip-Hop, Digital Media, and the Changing Face of Music Education

Science.gov (United States)

Thibeault, Matthew D.

2010-01-01

In this article, the author describes a true story about Dwayne Carter Jr., a rapper most music educators probably don't know but one who is beloved throughout the world as "Lil Wayne." Critics overwhelmingly proclaimed Lil Wayne the top rapper in the hip-hop game, and the album and his work leading up to it were universally regarded as some of…

Mourning a Lost Childhood: A Therapeutic Task.

Science.gov (United States)

Kulish, Nancy Mann

J. M. Barrie's popular story of Peter Pan depicts the never-neverland of an endless happy childhood. Analysis of the story and of J. M. Barrie's personal background, however, reveals that the tale is a conflicted solution to and separation from early childhood losses and disappointments. Themes of separation and reunion, redesertion and revenge…

Imaging retinal nerve fiber bundles using optical coherence tomography with adaptive optics.

Science.gov (United States)

Kocaoglu, Omer P; Cense, Barry; Jonnal, Ravi S; Wang, Qiang; Lee, Sangyeol; Gao, Weihua; Miller, Donald T

2011-08-15

Early detection of axonal tissue loss in retinal nerve fiber layer (RNFL) is critical for effective treatment and management of diseases such as glaucoma. This study aims to evaluate the capability of ultrahigh-resolution optical coherence tomography with adaptive optics (UHR-AO-OCT) for imaging the RNFL axonal bundles (RNFBs) with 3×3×3μm(3) resolution in the eye. We used a research-grade UHR-AO-OCT system to acquire 3°×3° volumes in four normal subjects and one subject with an arcuate retinal nerve fiber layer defect (n=5; 29-62years). Cross section (B-scans) and en face (C-scan) slices extracted from the volumes were used to assess visibility and size distribution of individual RNFBs. In one subject, we reimaged the same RNFBs twice over a 7month interval and compared bundle width and thickness between the two imaging sessions. Lastly we compared images of an arcuate RNFL defect acquired with UHR-AO-OCT and commercial OCT (Heidelberg Spectralis). Individual RNFBs were distinguishable in all subjects at 3° retinal eccentricity in both cross-sectional and en face views (width: 30-50μm, thickness: 10-15μm). At 6° retinal eccentricity, RNFBs were distinguishable in three of the five subjects in both views (width: 30-45μm, thickness: 20-40μm). Width and thickness RNFB measurements taken 7months apart were strongly correlated (p<0.0005). Mean difference and standard deviation of the differences between the two measurement sessions were -0.1±4.0μm (width) and 0.3±1.5μm (thickness). UHR-AO-OCT outperformed commercial OCT in terms of clarity of the microscopic retina. To our knowledge, these are the first measurements of RNFB cross section reported in the living human eye. Copyright © 2011 Elsevier Ltd. All rights reserved.

Dependence of electron beam instability growth rates on the beam-plasma system parameters

International Nuclear Information System (INIS)

Strangeway, R.J.

1982-01-01

Electron beam instabilites are studied by using a simple model for an electron beam streaming through a cold plasma, the beam being of finite width perpendicular to the ambient magnetic field. Through considerations of finite geometry and the coldness of the beam and background plasma, an instability similar to the two stream instability is assumed to be the means for wave growth in the system. Having found the maximum growth rate for one set of beam-plasma system parameters, this maximum growth rate is traced as these parameters are varied. The parameters that describe the system are the beam velocity (v/sub b/), electron gyrofrequency to ambient electron plasma frequency ratio (Ω/sub e//ω/sub p/e), the beam to background number density ratio (n/sub b//n/sub a/), and the beam width (a). When Ω/sub e//ω/sub p/e>1, a mode with Ω/sub e/<ω<ω/sub u/hr is found to be unstable, where Ω is the wave frequency and ω/sub u/hr is the upper hybrid resonance frequency. For low values of n/sub b//n/sub a/ and Ω/sub e/<ω/sub p/e, this mode is still present with ω/sub p/e<ω<ω/sub u/hr. If the beam density is large, n/sub b//n/sub a/approx. =1, the instability occures for frequencies just above the electron gyrofrequency. This mode may well be that observed in laboratory plasma before the system undergoes the beam-plasma discharge. There is another instability present, which occurs for ωapprox. =ω/sub p/e. The growth rates for this mode, which are generally larger than those found for the ωapprox. =ωuhr mode, are only weakly dependent on Ω/sub d//ω/sub p/e. That this mode is not always observed in the laboratory implies that some factors not considered in the present theory suppress this mode, specifically, finite beam length

African Journal of Urology - Vol 13, No 4 (2007)

African Journals Online (AJOL)

Caractéristiques cliniques du cancer de la prostate en Guinée. Résultats sur la période 2000-2006 · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A B Diallo, N Youwe Dombeu, A M Barry, O R Bah, I Bah, M Barry, M B Diallo, 280-287 ...

An Integrated Assessment of Progress in Robotic Perception and Semantic Navigation

Science.gov (United States)

2015-09-01

Navigation by Craig Lennon, Barry Bodt, Marshal Childers, Jean Oh, Arne Suppe, Luis Navarro-Serment, Robert Dean, Terrence Keegan , Chip Diberardino...Directorate, ARL Jean Oh, Arne Suppe, and Luis Navarro-Serment National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terrence Keegan ...AUTHOR(S) Craig Lennon, Barry Bodt, Marshal Childers, Jean Oh, Arne Suppe, Luis Navarro-Serment, Robert Dean, Terrence Keegan , Chip Diberardino

An Enhanced Role of the Economics Element of National Power in Military Operations: The Mexican Economy as a Case Study for U.S. Northern Command Theater Security Cooperation (TSC) Planning

Science.gov (United States)

2011-10-26

economic sectors. 6 Ibid. 7 Hugo G. Nutini and Barry L. Isaac, Social Stratification in Central...this reason, the U.S. military must consider scenarios to include countering increasingly dangerous drug cartels, intervening in a “migratory hurricane ...domestic- credit-private-sector-gdp (accessed OCTOBER 17, 2011). Nutini, Hugo G., and Barry L. Isaac. Social Stratification in Central Mexico: 1500-2000

Max Barry’s Jennifer Government and NationStates: neo-liberalism and the cultural public sphere = Jennifer Government, de Max Barry, e Estados-Nações: Neoliberalismo e a esfera pública da cultural

Directory of Open Access Journals (Sweden)

Purnima Bose

2008-01-01

Full Text Available In the United States, many people point to the corporatization of the media and the impoverishment of the public sphere as symptomatic of a crisis in democracy. While the mainstream media has not given much attention to popular anger against corporate globalization,literary works have started to explore this terrain, suggesting that the cultural public sphere is a parapolitical site for debates about economic neo-liberalism and its effects on people. This essayanalyzes the representation of neo-liberalism, corporate power, and resistance in Max Barry’s novel Jennifer Government and computer simulation game NationStates in the context of debates over globalization and the cultural public sphere.Muitas pessoas nos Estados Unidos alegam que a corporativismo dos meios de comunicação e o empobrecimento da esfera pública sãosintomas da crise na democracia. Enquanto os meios de comunicação principais não deram tanta importância à ira popular contra a globalização corporativa, muitos autores de obras literárias já começaram de analisar esse assunto. Sugerem que a esfera publica cultural é um lugar para-político para debates sobre o neoliberalismo econômico e suas conseqüências na população. Esse ensaio analisa a representação do neoliberalismo, poder corporativista e resistência no romance Jennifer Government, de Max Barry, e o jogo de computadorNationStates no contexto de debates sobre a globalização e a esfera pública cultural.

Cognitive alexithymia is associated with the degree of risk for psychosis.

Directory of Open Access Journals (Sweden)

Jorien van der Velde

Full Text Available Alexithymia is a personality construct denoting emotion processing problems. It has been suggested to encompass two dimensions: a cognitive and affective dimension. The cognitive dimension is characterized by difficulties in identifying, verbalizing and analyzing emotions, while the affective dimension reflects the level of emotional arousal and imagination. Alexithymia has been previously proposed as a risk factor for developing psychosis. More specifically, the two alexithymia dimensions might be differentially related to the vulnerability for psychosis. Therefore, we examined the two dimensions of alexithymia, measured with the BVAQ in 94 siblings of patients with schizophrenia, 52 subjects at ultra-high risk (UHR for developing psychosis, 38 patients with schizophrenia and 109 healthy controls. The results revealed that siblings and patients had higher levels of cognitive alexithymia compared to controls. In addition, subjects at UHR for psychosis had even higher levels of cognitive alexithymia compared to the siblings. The levels of affective alexithymia in siblings and patients were equal to controls. However, UHR individuals had significantly lower levels of affective alexithymia (i.e. higher levels of emotional arousal and fantasizing compared to controls. Alexithymia was further related to subclinical levels of negative and depressive symptoms. These findings indicate that alexithymia varies parametrically with the degree of risk for psychosis. More specifically, a type-II alexithymia pattern, with high levels of cognitive alexithymia and normal or low levels of affective alexithymia, might be a vulnerability factor for psychosis.

Non-destructive testing of layer-to-layer fusion of a 3D print using ultrahigh resolution optical coherence tomography

Science.gov (United States)

Israelsen, Niels M.; Maria, Michael; Feuchter, Thomas; Podoleanu, Adrian; Bang, Ole

2017-06-01

Within the last decade, 3D printing has moved from a costly approach of building mechanical items to the present state-of-the-art phase where access to 3D printers is now common, both in industry and in private places. The plastic printers are the most common type of 3D printers providing prints that are light, robust and of lower cost. The robustness of the structure printed is only maintained if each layer printed is properly fused to its previously printed layers. In situations where the printed component has to accomplish a key mechanical role there is a need to characterize its mechanical strength. This may only be revealed by in-depth testing in order to discover unwanted air-gaps in the structure. Optical coherence tomography (OCT) is an in-depth imaging method, that is sensitive to variations in the refractive index and therefore can resolve with high resolution translucid samples. We report on volume imaging of a 3D printed block made with 100% PLA fill. By employing ultrahigh resolution OCT (UHR-OCT) we show that some parts of the PLA volume reveal highly scattering interfaces which likely correspond to transitions from one layer to another. In doing so, we document that UHR-OCT can act as a powerful tool that can be used in detecting fractures between layers stemming from insufficient fusion between printed structure layers. UHR-OCT can therefore serve as an useful assessment method of quality of 3D prints.

Qualitative and quantitative aspects of information processing in first psychosis: latent class analyses in patients, at-risk subjects, and controls.

Science.gov (United States)

van Tricht, Mirjam J; Bour, Lo J; Koelman, Johannes H T M; Derks, Eske M; Braff, David L; de Wilde, Odette M; Boerée, Thijs; Linszen, Don H; de Haan, Lieuwe; Nieman, Dorien H

2015-04-01

We aimed to determine profiles of information processing deficits in the pathway to first psychosis. Sixty-one subjects at ultrahigh risk (UHR) for psychosis were assessed, of whom 18 converted to a first episode of psychosis (FEP) within the follow-up period. Additionally, 47 FEP and 30 control subjects were included. Using 10 neurophysiological parameters associated with information processing, latent class analyses yielded three classes at baseline. Class membership was related to group status. Within the UHR sample, two classes were found. Transition to psychosis was nominally associated with class membership. Neurophysiological profiles were unstable over time, but associations between specific neurophysiological components at baseline and follow-up were found. We conclude that certain constellations of neurophysiological variables aid in the differentiation between controls and patients in the prodrome and after first psychosis. Copyright © 2014 Society for Psychophysiological Research.

Browse Title Index

African Journals Online (AJOL)

Items 51 - 100 of 721 ... AB Diallo, I Bah, AM Barry, NY Dombeu, M Barry, MB Diallo. Vol 14, No 3 (2008):, Article Original Hydronéphrose géante de l\\'enfant : Aspects diagnostiques et thérapeutiques, Abstract PDF. B Diao, PA Fall, GM Ngom, Y Sow, A Thiam, AK Ndoye, M Baret, BA Diagne. Vol 22, No 3 (2016), Ask-Upmark ...

ORTHOIMAGERY, WAYNE COUNTY, GEORGIA, USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The original countywide mosaic from the NAIP was converted to grayscale for mapping purposes with the original compression. This metadata contains the information...

Belle Physics at Wayne State

International Nuclear Information System (INIS)

Cinabro, David

2016-01-01

The major goals of our work on Belle II were to complete our contributions, a 64-channel PIN diode-based radiation monitor, to the precursor detector called Beast II and the electronics for the endcap K-Long/Muon (E-KLM) detector. This was done by Professor Cinabro, Technician Gutierrez, and undergraduate labor supported by US-Japan funds. Professor Bonvicini through US-Japan funds led the development and installation of a beamstrahlung monitor system in the Belle II interaction region. Graduate students Farhat and DiCarlo worked on this. We also worked on charm physics analysis.

TERRAIN, WAYNE COUNTY, KENTUCKY USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix N: Data Capture Standards, describes the digital topographic data that was used to create...

Social cognition in patients at ultra-high risk for psychosis

DEFF Research Database (Denmark)

Glenthøj, Louise B.; Fagerlund, Birgitte; Hjorthøj, Carsten

2016-01-01

Objective: Patients at ultra-high risk (UHR) for psychosis show significant impairments in functioning. It is essential to determine which factors influence functioning, as it may have implications for intervention strategies. This study examined whether social cognitive abilities and clinical...

Pre-pulse inhibition and striatal dopamine in subjects at an ultra-high risk for psychosis

NARCIS (Netherlands)

de Koning, Mariken B.; Bloemen, Oswald J. N.; van Duin, Esther D. A.; Booij, Jan; Abel, Kathryn M.; de Haan, Lieuwe; Linszen, Don H.; van Amelsvoort, Thérèse A. M. J.

2014-01-01

Reduced prepulse inhibition (PPI) of the acoustic startle response is thought to represent a robust biomarker in schizophrenia. Reduced PPI has been demonstrated in subjects at ultra high risk (UHR) for developing psychosis. Imaging studies report disruption of striatal dopaminergic

STS-114: Discovery Launch Readiness Press Conference

Science.gov (United States)

2005-01-01

Michael Griffin, NASA Administrator; Wayne Hale, Space Shuttle Deputy Program Manager; Mike Wetmore, Director of Shuttle Processing; and 1st Lieutenant Mindy Chavez, Launch Weather Officer-United States Air Force 45th Weather Squadron are in attendance for this STS-114 Discovery launch readiness press conference. The discussion begins with Wayne Hale bringing to the table a low level sensor device for everyone to view. He talks in detail about all of the extensive tests that were performed on these sensors and the completion of these ambient tests. Chavez presents her weather forecast for the launch day of July 26th 2005. Michael Griffin and Wayne Hale answer questions from the news media pertaining to the sensors and launch readiness. The video ends with footage of Pilot Jim Kelly and Commander Eileen Collins conducting test flights in a Shuttle Training Aircraft (STA) that simulates Space Shuttle landing.

Child Maltreatment and Clinical Outcome in Individuals at Ultra-High Risk for Psychosis in the EU-GEI High Risk Study

NARCIS (Netherlands)

Kraan, Tamar C.; Velthorst, Eva; Themmen, Manouk; Valmaggia, Lucia; Kempton, Matthew J.; McGuire, Phillip; Van Os, Jim; Rutten, Bart P.F.; Smit, Filip; De Haan, Lieuwe; Van Der Gaag, Mark; McGuire, Philip; Valmaggia, Lucia R.; Calem, Maria; Tognin, Stefania; Modinos, Gemma; Burger, Nadine; Van Dam, Daniella S.; Barrantes-Vidal, Neus; Domínguez-Martínez, Tecelli; Cristóbal-Narváez, Paula; Kwapil, Thomas R.; Monsonet-Bardají, Manel; Hinojosa, Lídia; Riecher-Rössler, Anita; Borgwardt, Stefan; Rapp, Charlotte; Ittig, Sarah; Studerus, Erich; Smieskova, Renata; Bressan, Rodrigo; Gadelha, Ary; Brietzke, Elisa; Asevedo, Graccielle; Asevedo, Elson; Zugman, Andre; Ruhrmann, Stephan; Gebhard, Dominika; Arnhold, Julia; Klosterkötter, Joachim; Nordholm, Dorte; Randers, Lasse; Krakauer, Kristine; Naumann, Tanya Louise; Glenthøj, Louise Birkedal; Nordentoft, Merete; De Hert, Marc; Van Winkel, Ruud; Nelson, Barnaby; McGorry, Patrick

2018-01-01

Background: Child maltreatment has been associated with a wide range of mental disorders in adulthood. Whether child maltreatment is specifically associated with psychosis risk in individuals at ultra-high risk (UHR) for psychosis, or leads to a general vulnerability for overall psychopathology in

Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis

NARCIS (Netherlands)

Rietdijk, J.; Ising, H.K.; Dragt, S.; Klaassen, R.; Nieman, D.; Wunderink, L.; Cuijpers, P.; Linszen, D.; van der Gaag, M.

2013-01-01

Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression

Pärt, Arvo: "Litany" / Barry Witherden

Index Scriptorium Estoniae

Witherden, Barry

1996-01-01

Uuest heliplaadist "Pärt, Arvo: "Litany". Litany. Psalom. Trisagion. The Hilliard Ensemble, Tallinn Chamber Orchestra, Estonian Philharmonic Chamber Orchestra, Estonian Philharmonic Chamber Choir, Tõnu Kaljuste. Orchestre de chambre de Lituanie, Saulius Sondeckis". ECM New Series ECM 1592, distribution Polygram 449 810-2 (CD:158F)

Social environments and interpersonal distance regulation in psychosis: A virtual reality study.

Science.gov (United States)

Geraets, Chris N W; van Beilen, Marije; Pot-Kolder, Roos; Counotte, Jacqueline; van der Gaag, Mark; Veling, Wim

2018-02-01

Experimentally studying the influence of social environments on mental health and behavior is challenging, as social context is difficult to standardize in laboratory settings. Virtual Reality (VR) enables studying social interaction in terms of interpersonal distance in a more ecologically valid manner. Regulation of interpersonal distance may be abnormal in patients with psychotic disorders and influenced by environmental stress, symptoms or distress. To investigate interpersonal distance in people with a psychotic disorder and at ultrahigh risk for psychosis (UHR) compared to siblings and controls in virtual social environments, and explore the relationship between clinical characteristics and interpersonal distance. Nineteen UHR patients, 52 patients with psychotic disorders, 40 siblings of patients with a psychotic disorder and 47 controls were exposed to virtual cafés. In five virtual café visits, participants were exposed to different levels of social stress, in terms of crowdedness, ethnicity and hostility. Measures on interpersonal distance, distress and state paranoia were obtained. Baseline measures included trait paranoia, social anxiety, depressive, positive and negative symptoms. Interpersonal distance increased when social stressors were present in the environment. No difference in interpersonal distance regulation was found between the groups. Social anxiety and distress were positively associated with interpersonal distance in the total sample. This VR paradigm indicates that interpersonal distance regulation in response to environmental social stressors is unaltered in people with psychosis or UHR. Environmental stress, social anxiety and distress trigger both people with and without psychosis to maintain larger interpersonal distances in social situations. Copyright © 2017 Elsevier B.V. All rights reserved.

Technical note: a landmark-based approach to the study of the ear ossicles using ultra-high-resolution X-ray computed tomography data.

Science.gov (United States)

Schmidt, Jodi L; Cole, Theodore M; Silcox, Mary T

2011-08-01

Previous study of the ear ossicles in Primates has demonstrated that they vary on both functional and phylogenetic bases. Such studies have generally employed two-dimensional linear measurements rather than three-dimensional data. The availability of Ultra- high-resolution X-ray computed tomography (UhrCT) has made it possible to accurately image the ossicles so that broadly accepted methodologies for acquiring and studying morphometric data can be applied. Using UhrCT data also allows for the ossicular chain to be studied in anatomical position, so that it is possible to consider the spatial and size relationships of all three bones. One issue impeding the morphometric study of the ear ossicles is a lack of broadly recognized landmarks. Distinguishing landmarks on the ossicles is difficult in part because there are only two areas of articulation in the ossicular chain, one of which (the malleus/incus articulation) has a complex three-dimensional form. A measurement error study is presented demonstrating that a suite of 16 landmarks can be precisely located on reconstructions of the ossicles from UhrCT data. Estimates of measurement error showed that most landmarks were highly replicable, with an average CV for associated interlandmark distances of less than 3%. The positions of these landmarks are chosen to reflect not only the overall shape of the bones in the chain and their relative positions, but also functional parameters. This study should provide a basis for further examination of the smallest bones in the body in three dimensions. Copyright © 2011 Wiley-Liss, Inc.

Diagnostic validity of the Eppendorf Schizophrenia Inventory (ESI): a self-report screen for ultrahigh risk and acute psychosis

NARCIS (Netherlands)

Niessen, Maurice A. J.; Dingemans, Peter M. A. J.; van de Fliert, Reinaud; Becker, Hiske E.; Nieman, Dorien H.; Linszen, Don

2010-01-01

Providers of mental health services need tools to screen for acute psychosis and ultrahigh risk (UHR) for transition to psychosis in help-seeking individuals. In this study, the Eppendorf Schizophrenia Inventory (ESI) was examined as a screening tool and for its ability to correctly predict

Environmental factors and social adjustment as predictors of a first psychosis in subjects at ultra high risk

NARCIS (Netherlands)

Dragt, Sara; Nieman, Dorien H.; Veltman, Doede; Becker, Hiske E.; van de Fliert, Reinaud; de Haan, Lieuwe; Linszen, Don H.

2011-01-01

BACKGROUND: The onset of schizophrenia is associated with genetic, symptomatic, social and environmental risk factors. The aim of the present study was to determine which environmental factors may contribute to a prediction of a first psychotic episode in subjects at Ultra High Risk (UHR) for

Direct Experiments on the Ocean Disposal of Fossil Fuel CO2

Energy Technology Data Exchange (ETDEWEB)

Barry, James, P.

2010-05-26

Funding from DoE grant # FG0204-ER63721, Direct Experiments on the Ocean Disposal of Fossil Fuel CO2, supposed several postdoctoral fellows and research activities at MBARI related to ocean CO2 disposal and the biological consequences of high ocean CO2 levels on marine organisms. Postdocs supported on the project included Brad Seibel, now an associate professor at the University of Rhode Island, Jeff Drazen, now an associate professor at the University of Hawaii, and Eric Pane, who continues as a research associate at MBARI. Thus, the project contributed significantly to the professional development of young scientists. In addition, we made significant progress in several research areas. We continued several deep-sea CO2 release experiments using support from DoE and MBARI, along with several collaborators. These CO2 release studies had the goal of broadening our understanding of the effects of high ocean CO2 levels on deep sea animals in the vicinity of potential release sites for direct deep-ocean carbon dioxide sequestration. Using MBARI ships and ROVs, we performed these experiments at depths of 3000 to 3600 m, where liquid CO2 is heavier than seawater. CO2 was released into small pools (sections of PVC pipe) on the seabed, where it dissolved and drifted downstream, bathing any caged animals and sediments in a CO2-rich, low-pH plume. We assessed the survival of organisms nearby. Several publications arose from these studies (Barry et al. 2004, 2005; Carman et al. 2004; Thistle et al. 2005, 2006, 2007; Fleeger et al. 2006, 2010; Barry and Drazen 2007; Bernhard et al. 2009; Sedlacek et al. 2009; Ricketts et al. in press; Barry et al, in revision) concerning the sensitivity of animals to low pH waters. Using funds from DoE and MBARI, we designed and fabricated a hyperbaric trap-respirometer to study metabolic rates of deep-sea fishes under high CO2 conditions (Drazen et al, 2005), as well as a gas-control aquarium system to support laboratory studies of the

Cyber Practices: What Can the U.S. Air Force Learn from the Commercial Sector?

Science.gov (United States)

2015-01-01

dam/lockheed/data/isgs/documents/LMCSA%20Ov erview%20Fact%20Sheet_Final%20%282%29. pdf Lunt, Barry, Joseph J. Ekstrom, Sandra Gorka, Gregory Hislop ...Electronics Engineers, 2006, p. 33. 21 Barry Lunt, Joseph J. Ekstrom, Sandra Gorka, Gregory Hislop , Reza Kamali, Eydie Lawson, Richard LeBlanc, Jacob Miller...1 (January 1980 ). 106 Daft, 2008, p. 17. 107 Gerald D. Bell, “Determinants of Span of Control,” American Journal of Sociology 73, no. 1 (1967

Trauma and recent life events in individuals at ultra high risk for psychosis: Review and meta-analysis

NARCIS (Netherlands)

Kraan, T.; Velthorst, E.; Smit, H.F.E.; de Haan, L.; van der Gaag, M.

2015-01-01

Background: Childhood trauma and recent life-events have been related to psychotic disorders. The aim of the present study was to examine whether childhood trauma and recent life-events are significantly more prevalent in patients at Ultra High Risk (UHR) of developing a psychotic disorder compared

Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

NARCIS (Netherlands)

Hartmann, Jessica A.; McGorry, Patrick D.; Schmidt, Stefanie J.; Amminger, G. Paul; Yuen, Hok Pan; Markulev, Connie; Berger, Gregor E.; Chen, Eric Y. H.; de Haan, Lieuwe; Hickie, Ian B.; Lavoie, Suzie; McHugh, Meredith J.; Mossaheb, Nilufar; Nieman, Dorien H.; Nordentoft, Merete; Riecher-Rössler, Anita; Schäfer, Miriam R.; Schlögelhofer, Monika; Smesny, Stefan; Thompson, Andrew; Verma, Swapna Kamal; Yung, Alison R.; Nelson, Barnaby

2017-01-01

Background: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis. However, CBT is an umbrella term for a plethora of different strategies, and little is known about the association between the intensity and content of CBT and the

Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions

Directory of Open Access Journals (Sweden)

Yulia Zaytseva

2013-01-01

Full Text Available Recent interest in the early course of schizophrenia accentuated altered cognition prior to the onset. Ultrahigh risk (UHR individuals with attenuated positive symptoms and transient psychotic episodes demonstrate neurocognitive deficits across multiple domains such as memory, executive functioning, and processing speed which are consistent with similar disturbances identified in patients with a first episode of schizophrenia. Cognitive remediation (CR approaches representing a broad set of activities are aimed to restore or improve cognitive functioning. CR proved to be effective in modulating the cognitive dysfunction in schizophrenia but is rarely used in ultrahigh risk individuals. From the clinical prospective, a better understanding of cognitive functioning in at-risk states is essential for the development of optimal early intervention models. In the review, we highlight the intervention targets, notably the specific cognitive deficits in at risk individuals which preceed the transition to psychosis and emphasize the need of the additional studies using CR approaches in UHR group aiming to enhance cognition and therefore mediate functional improvement.

Prof. Bernard R. Cooper (1936 - 2013)

International Nuclear Information System (INIS)

Lederman, David

2014-01-01

Bernard (Barry) R. Cooper, Claude W. Benedum professor emeritus at West Virginia University, passed away at age 77 on June 10, 2013 in Morgantown, West Virginia. A fellow of the American Physical Society, Barry was a theoretical condensed matter physicist best known for his contributions to the fundamental understanding of the magnetic and electronic properties of transition, rare earth, and actinide metals. He also contributed to early efforts to accurately calculate and predict the properties of materials using first-principles methods

Learning Basic Mechatronics through Helicopter Workshop

OpenAIRE

Adzly Anuar; Maryam Huda Ahmad Phesal; Azrul Abidin Zakaria; Goh Chin Hock; Sivadass Thiruchelvam; Dickson Neoh Tze How; Muhammad Fahmi Abdul Ghani; Khairul Salleh Mohamed Sahari

2014-01-01

In recent years, technologies related to mechatronics and robotics is available even to elementary level students. It is now common to see schools in Malaysia using Lego Mindstorm as a tool for active learning on mechatronics and robotics. A new yet interesting way of learning mechatronics and robotics is introduced by Dr. Dan Barry, a former astronaut and his son Andrew Barry during their visit to Malaysia. The kits used are based on a 4-channel RC helicopter, Arduino Uno microcontroller, IR...

Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

DEFF Research Database (Denmark)

Hartmann, Jessica A.; McGorry, Patrick D.; Schmidt, Stefanie J.

2017-01-01

Background: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis. However, CBT is an umbrella term for a plethora of different strategies, and little is known about the association between the intensity and content of CBT and the se...

Subjective effects of cannabis before the first psychotic episode

NARCIS (Netherlands)

Peters, Bart D.; de Koning, Pelle; Dingemans, Peter; Becker, Hiske; Linszen, Don H.; de Haan, Lieuwe

2009-01-01

Objective: The aim of the present study was to gain more insight into the positive and negative effects of cannabis in the prodromal phase of schizophrenia and in the ultrahigh-risk (UHR) state for psychosis. Method: A theory-driven questionnaire was used to examine subjective effects in the

Microsoft Office Excel 2007 data analysis and business modeling

CERN Document Server

Winston, Wayne L

2007-01-01

Master the analysis and business modeling techniques that help you transform your data into bottom-line results. Award-winning business professor and corporate consultant Wayne Winston shares the best of his real-world experience in this practical guide-now updated for Excel 2007. Use Wayne's proven practices and hands-on exercises to help you work smarter, make better decisions, and gain the competitive edge. Solve real-world business problems with Excel 2007! Maximize profits-determine NPV, optimize your product mix, calculate ROICreate best, worst, and most-likely case scenarios for sal

Normal values of iodine - 131 uptake in 24 hours, in Rio Grande do Norte, Brazil

International Nuclear Information System (INIS)

Oliveira Filho, T.F. de; Oliveira, C.F.F. de

Thorough clinical exams on all patients come to the radioisotope Laboratory at UFRN, where carried out attempting to select those patients with thyroids considered to be clinically normal. After wayne tests for hypo and hyperthyroidism were carried out, 100 patients were considered to be fit for the research. All of them had an impalpable and asympitomatic thyroid. Waynes clinical indices were precisely revealed in 93% of cases. It was concluded that the normal values of uptake of 131 I during the 24 hours in RGN varied between 14% and 44% [pt

Effects of Cryospheric Change on Alpine Hydrology: Combining a Model With Observations in the Upper Reaches of the Hei River, China

Science.gov (United States)

Chen, R.; Wang, G.; Yang, Y.; Liu, J.; Han, C.; Song, Y.; Liu, Z.; Kang, E.

2018-04-01

Cryospheric changes have great effects on alpine hydrology, but these effects are still unclear owing to rare observations and suitable models in the western cold regions of China. Based on long-term field observations in the western cold regions of China, a cryospheric basin hydrological model was proposed to evaluate the cryospheric effects on streamflow in the upper Hei River basin (UHR), and the relationship between the cryosphere and streamflow was further discussed with measured data. The Norwegian Earth System Model outputs were chosen to project future streamflow under scenarios Representative Concentration Pathways (RCP)2.6, RCP4.5, and RCP8.5. The cryospheric basin hydrological model results were well validated by the measured precipitation, streamflow, evapotranspiration, soil temperature, glacier and snow cover area, and the water balance of land cover in the UHR. The moraine-talus region contributed most of the runoff (60%), even though it made up only about 20% of the area. On average, glacier and snow cover, respectively, contributed 3.5% and 25.4% of the fresh water to the streamflow in the UHR between 1960 and 2013. Because of the increased air temperature (2.9°C/54a) and precipitation (69.2 mm/54a) over the past 54 years, glacial and snowmelt runoff increased by 9.8% and 12.1%, respectively. The increase in air temperature brought forward the snowmelt flood peak and increased the winter flow due to permafrost degradation. Glaciers may disappear in the near future because of their small size, but snowmelt would increase due to increases in snowfall in the higher mountainous areas, and the basin runoff would increase slightly in the future.

Computing handbook information systems and information technology

CERN Document Server

Topi, Heikki

2014-01-01

Disciplinary Foundations and Global ImpactEvolving Discipline of Information Systems Heikki TopiDiscipline of Information Technology Barry M. Lunt and Han ReichgeltInformation Systems as a Practical Discipline Juhani IivariInformation Technology Han Reichgelt, Joseph J. Ekstrom, Art Gowan, and Barry M. LuntSociotechnical Approaches to the Study of Information Systems Steve Sawyer and Mohammad Hossein JarrahiIT and Global Development Erkki SutinenUsing ICT for Development, Societal Transformation, and Beyond Sherif KamelTechnical Foundations of Data and Database ManagementData Models Avi Silber

BASE MAP for WAYNE COUNTY, TENNESSEE

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Basemap datasets comprise six of the seven FGDC themes of geospatial data that are used by most GIS applications (Note: the seventh framework theme, orthographic...

Diagnostic Validity of the Eppendorf Schizophrenia Inventory (ESI): A Self-Report Screen for Ultrahigh Risk and Acute Psychosis

Science.gov (United States)

Niessen, Maurice A. J.; Dingemans, Peter M. A. J.; van de Fliert, Reinaud; Becker, Hiske E.; Nieman, Dorien H.; Linszen, Don

2010-01-01

Providers of mental health services need tools to screen for acute psychosis and ultrahigh risk (UHR) for transition to psychosis in help-seeking individuals. In this study, the Eppendorf Schizophrenia Inventory (ESI) was examined as a screening tool and for its ability to correctly predict diagnostic group membership (e.g., help seeking, mild…

Comunicació d'èxit : Estudi del cas Rec.0 Experimental Stores

OpenAIRE

Farreras Pérez, Laura

2015-01-01

El present projecte estudia la comunicació de barri a partir de la iniciativa Rec.0 Experimental Stores. És la posada en escena del concepte 'pop up stores' al vell barri industrial del Rec d'Igualada. Descomptes radicals en una experiència de compra diferent, on el valor afegit ve donat per les activitats complementàries. La proposta d'un pla de comunicació culmina l'estudi. El presente proyecto estudia la comunicación de barrio a partir de la iniciativa Rec.0 Experimental Stores. Es la p...

Pärt, Arvo: De profundis / Barry Witherden

Index Scriptorium Estoniae

Witherden, Barry

1997-01-01

Uuest heliplaadist "Pärt, Arvo: De profundis. Missa Sillabica. Solfeggio. And one of the Pharisees. Cantate Domino. Summa. Seven Magnificat Antiphons. The Beautitudes. Magnificat. Christopher Bowers-Broadbent (org.), Daniel Kennedy (perc.). Theatre of Voices / Paul Hillier (bass)". Harmonia Mundi HMU40 7182; HMU90 7182 (76 minutes:DDD)

1834-IJBCS-Article-Dr Barry Mamoudou Mamoudou+

African Journals Online (AJOL)

hp

of Spirulina on Blood glucose,. Glycosylated Hemoglobin and Lipid. Profile of Male Non-Insulin Dependent. Diabetics. Asian J. Exp. Biol. SCI., 1(1):. 36-46. Branger B, Cadudal JL, Delobel M, Ouoba H,. Yameogo P, Ouedraogo D. 2003. Spiruline as a food supplement in case of infant malnutrition in Burkina-Faso. Arch.

Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

Science.gov (United States)

Gonzalo, I. B.; Maria, M.; Engelsholm, R. D.; Feuchter, T.; Leick, L.; Moselund, P. M.; Podoleanu, A.; Bang, O.

2018-02-01

Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC generation process [6-9]. This intensity noise from the SC source can limit the performance of OCT, resulting in a reduced signal-to-noise ratio (SNR) [10-12]. Much work has been done to reduce the noise of the SC sources for instance with fiber tapers [7,8] or increasing the repetition rate of the pump laser for averaging in the spectrometer [10,12]. An alternative approach is to use all-normal dispersion (ANDi) fibers [13,14] to generate SC light from well-known coherent nonlinear processes [15-17]. In fact, reduction of SC noise using ANDi fibers compared to anomalous dispersion SC pumped by sub-picosecond pulses has been recently demonstrated [18], but a cladding mode was used to stabilize the ANDi SC. In this work, we characterize the noise performance of a femtosecond pumped ANDi based SC and a commercial SC source in an UHR-OCT system at 1300 nm. We show that the ANDi based SC presents exceptional noise properties compared to a commercial source. An improvement of 5 dB in SNR is measured in the UHR-OCT system, and the noise behavior resembles that of a superluminiscent diode. This preliminary study is a step forward towards development of an ultra-low noise SC source at 1300 nm for ultra-high resolution OCT.

PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia.

Science.gov (United States)

Di Biase, M A; Zalesky, A; O'keefe, G; Laskaris, L; Baune, B T; Weickert, C S; Olver, J; McGorry, P D; Amminger, G P; Nelson, B; Scott, A M; Hickie, I; Banati, R; Turkheimer, F; Yaqub, M; Everall, I P; Pantelis, C; Cropley, V

2017-08-29

We examined putative microglial activation as a function of illness course in schizophrenia. Microglial activity was quantified using [ 11 C](R)-(1-[2-chrorophynyl]-N-methyl-N-[1-methylpropyl]-3 isoquinoline carboxamide ( 11 C-(R)-PK11195) positron emission tomography (PET) in: (i) 10 individuals at ultra-high risk (UHR) of psychosis; (ii) 18 patients recently diagnosed with schizophrenia; (iii) 15 patients chronically ill with schizophrenia; and, (iv) 27 age-matched healthy controls. Regional-binding potential (BP ND ) was calculated using the simplified reference-tissue model with four alternative reference inputs. The UHR, recent-onset and chronic patient groups were compared to age-matched healthy control groups to examine between-group BP ND differences in 6 regions: dorsal frontal, orbital frontal, anterior cingulate, medial temporal, thalamus and insula. Correlation analysis tested for BP ND associations with gray matter volume, peripheral cytokines and clinical variables. The null hypothesis of equality in BP ND between patients (UHR, recent-onset and chronic) and respective healthy control groups (younger and older) was not rejected for any group comparison or region. Across all subjects, BP ND was positively correlated to age in the thalamus (r=0.43, P=0.008, false discovery rate). No correlations with regional gray matter, peripheral cytokine levels or clinical symptoms were detected. We therefore found no evidence of microglial activation in groups of individuals at high risk, recently diagnosed or chronically ill with schizophrenia. While the possibility of 11 C-(R)-PK11195-binding differences in certain patient subgroups remains, the patient cohorts in our study, who also displayed normal peripheral cytokine profiles, do not substantiate the assumption of microglial activation in schizophrenia as a regular and defining feature, as measured by 11 C-(R)-PK11195 BP ND .

Four-channel multidetector-row computed tomography in the evaluation of facial fractures - optimized parameters for acquisition and multiplanar reformation

International Nuclear Information System (INIS)

Omid, P. M.

2002-08-01

The first part of this thesis is designed to give the reader a comprehensive survey on the complex basic principles of computed tomography (CT), from the early beginning to the recent development of multidetector-row CT (MD-CT). Attention is focused on imaging of trauma in general and on imaging of facial fractures in particular. The second part of this thesis describes a clinical study performed to optimize acquisition protocols and multiplanar reformation (MPR) algorithms for the evaluation of facial fractures using MD-CT, which has not been yet described in literature. For this study, a cadaver head with artificial blunt facial trauma was examined using a 4-channel MD-CT scanner. The influence of acquisition parameters (collimation: 2x0.5 mm/4x1 mm/4x2.5 mm; tube current: 120 mAs/90 mAs/60 mAs), image reconstruction algorithms (standard vs. ultra-high resolution (UHR) modes; reconstructed slice thicknesses: 0.5 mm/1 mm/3 mm; increment: 0.3 mm/0.6 mm/1.5 mm), and reformation algorithms (slice thicknesses: 0.5 mm/1 mm/3 mm; overlap: 0.5 mm/1 mm/3 mm) on detectability of facial fractures in MPRs with MD-CT was analyzed. Effects of algorithms and parameters on image noise, artifacts and delineation of soft tissues were evaluated. The results of this study reliably demonstrate that fracture detection was significantly higher with thin MPRs (0.5/0.5 mm, 1/0.5 mm, 1/1 mm) (p = 0 .014) acquired with 2x0.5 mm collimation (p = 0 .046), in UHR mode (p .0005) with 120 mAs (p = 0 .025). Inter-observer variability showed very good agreement (κ > = 0 .942). Non-UHR mode, lower mAs and thick MPRs (3/0.5 mm, 3/1 mm, 3/0.5 mm) showed significantly decreased detectability. (author)

Increased Saccadic Rate during Smooth Pursuit Eye Movements in Patients at Ultra High Risk for Developing a Psychosis

Science.gov (United States)

van Tricht, M. J.; Nieman, D. H.; Bour, L. J.; Boeree, T.; Koelman, J. H. T. M.; de Haan, L.; Linszen, D. H.

2010-01-01

Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR…

Checking the predictive accuracy of basic symptoms against ultra high-risk criteria and testing of a multivariable prediction model: Evidence from a prospective three-year observational study of persons at clinical high-risk for psychosis.

Science.gov (United States)

Hengartner, M P; Heekeren, K; Dvorsky, D; Walitza, S; Rössler, W; Theodoridou, A

2017-09-01

The aim of this study was to critically examine the prognostic validity of various clinical high-risk (CHR) criteria alone and in combination with additional clinical characteristics. A total of 188 CHR positive persons from the region of Zurich, Switzerland (mean age 20.5 years; 60.2% male), meeting ultra high-risk (UHR) and/or basic symptoms (BS) criteria, were followed over three years. The test battery included the Structured Interview for Prodromal Syndromes (SIPS), verbal IQ and many other screening tools. Conversion to psychosis was defined according to ICD-10 criteria for schizophrenia (F20) or brief psychotic disorder (F23). Altogether n=24 persons developed manifest psychosis within three years and according to Kaplan-Meier survival analysis, the projected conversion rate was 17.5%. The predictive accuracy of UHR was statistically significant but poor (area under the curve [AUC]=0.65, Pthinking of binary at-risk criteria is necessary in order to improve the prognosis of psychotic disorders. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Editorial Note

Science.gov (United States)

2016-02-01

As from January 2016, Dr. Andrew Barry and Dr. Andrea Rinaldo have retired as Editors of Advances in Water Resources. Dr Barry has been a long serving Editor for 14 years, beginning this role on January 1, 2002. During this time he has served the science community with dedication, commitment, and diligence while bringing to the journal a strong vision and a wealth of knowledge that has tremendously improved the visibility and impact of Advances in Water Resources. Throughout this period he has also broadened the scope of the journal by adapting to the new emerging needs of the field through proactively seeking and promoting numerous special issues, which have now become a hallmark of the journal. The importance of obtaining high quality reviews and timeliness in decision-making, have always been a priority under Dr Barry's Editorship. It is clear that Advances in Water Resources and the community which it serves, has benefited enormously under Andrew's tenure and we will miss his energy, enthusiasm and passion for hydrologic science.

Caractérisation de la perméabilité des couches constituant la barrière passive des installations de stockage de déchets non dangereux Permeability characterization of the geological barrier of non dangerous landfill sites

Directory of Open Access Journals (Sweden)

Mouthier B.

2012-09-01

Full Text Available Pour obtenir son autorisation d’exploiter, une Installation de Stockage de Déchets Non Dangereux (ISDND doit justifier réglementairement sa favorabilité géologique. Le « Guide de bonnes pratiques pour les reconnaissances géologiques » de l’AFNOR fournit les critères d’aptitude du site à recevoir une ISDND et les moyens à mettre en œuvre, dont ceux qui concernent la perméabilité des couches géologiques qui protègent le milieu naturel. La mesure de la perméabilité in situ, en forage, des matériaux peu à très peu perméables des deux couches de la barrière de sécurité passive, est une opération délicate qui nécessite une mise en œuvre soignée respectant les normes appropriées, choisies en fonction des gammes de perméabilité attendues. Plusieurs types d’essai en forage sont présentés. In order to get administrative authorization, a non dangerous waste landfill site (ISDND, must justify a favourable geological context, which follows the AFNOR “Guide de bonnes pratiques pour les reconnaissances géologiques ». Criteria and technical means are described among which the in situ and lab permeability determination processes. The low and very low permeability coefficient to be measured within the deep argillaceous formations of a landfill site, is a delicate operation which must be representative and accurate. Depending the permeability range, several norms are proposed.

El procés d'avaluació i intervenció psicològica a pacients amb trastorns per abús d' alcohol i/o altres substàncies psicotròpiques

OpenAIRE

Trasovares Navarrete, María Victoria

2004-01-01

Aquest treball, realitzat al Centre d'Atenció i Seguiment de Drogodependències (CASD) de Nou Barris, ha tingut com a objectiu principal observar el rol del psicòleg clínic en el procés d'avaluació i intervenció psicoterapèutica en pacients que presenten un trastorn per dependència de substàncies psicotròpiques. Este trabajo, realizado en el Centro de Atención y Seguimiento de Drogodependencias (CASD) de Nou Barris, ha tenido como principal objetivo observar el rol del psicólogo clínico en ...

78 FR 51139 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

Science.gov (United States)

2013-08-20

...: Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department of.... regions. The new Purpose statement no longer includes the wording ``other agricultural uses.'' Readability...

76 FR 31387 - Kentucky Disaster # KY-00040

Science.gov (United States)

2011-05-31

..., Bullitt, Caldwell, Calloway, Carlisle, Carter, Fulton, Grayson, Greenup, Hart, Henderson, Hopkins, Larue...: Henry, Obion, Weakley. West Virginia: Wayne. The Interest Rates are: Percent For Physical Damage...

Kroonitud demagoog ja sajatavad leedid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

William Shakespeare'i "Kuningas Richard Kolmas", lavastaja Barrie Rutter (Inglismaa), esietendus Vanemuise teatri Sadamateatris 17. oktoobril. Lisaks pealkirjastamata lavastuse tutvustus, autor: E. S.

Residential roof condition assessment system using deep learning

Science.gov (United States)

Wang, Fan; Kerekes, John P.; Xu, Zhuoyi; Wang, Yandong

2018-01-01

The emergence of high resolution (HR) and ultra high resolution (UHR) airborne remote sensing imagery is enabling humans to move beyond traditional land cover analysis applications to the detailed characterization of surface objects. A residential roof condition assessment method using techniques from deep learning is presented. The proposed method operates on individual roofs and divides the task into two stages: (1) roof segmentation, followed by (2) condition classification of the segmented roof regions. As the first step in this process, a self-tuning method is proposed to segment the images into small homogeneous areas. The segmentation is initialized with simple linear iterative clustering followed by deep learned feature extraction and region merging, with the optimal result selected by an unsupervised index, Q. After the segmentation, a pretrained residual network is fine-tuned on the augmented roof segments using a proposed k-pixel extension technique for classification. The effectiveness of the proposed algorithm was demonstrated on both HR and UHR imagery collected by EagleView over different study sites. The proposed algorithm has yielded promising results and has outperformed traditional machine learning methods using hand-crafted features.

76 FR 59162 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-National Center...

Science.gov (United States)

2011-09-23

.... Specifically, Anglicotech LLC, Washington, DC; Battelle, Columbus, OH; Baxter Healthcare Corporation, Round...; ARC Technology Solutions, LLC, Nashua, NH; BAE Systems, Wayne, NJ; BCT Technology, Inc., Keene, NH...

Diagnostic and Prognostic Significance of DSM-5 Attenuated Psychosis Syndrome in Services for Individuals at Ultra High Risk for Psychosis.

Science.gov (United States)

Fusar-Poli, Paolo; De Micheli, Andrea; Cappucciati, Marco; Rutigliano, Grazia; Davies, Cathy; Ramella-Cravaro, Valentina; Oliver, Dominic; Bonoldi, Ilaria; Rocchetti, Matteo; Gavaghan, Lauren; Patel, Rashmi; McGuire, Philip

2018-02-15

The diagnostic and prognostic significance of the DSM-5-defined Attenuated Psychosis Syndrome (DSM-5-APS) in individuals undergoing an ultra high risk (UHR) clinical assessment for suspicion of psychosis risk is unknown. Prospective cohort study including all consecutive help-seeking individuals undergoing both a DSM-5-APS and a Comprehensive Assessment of At Risk Mental States (CAARMS 12/2006) assessment for psychosis risk at the Outreach and Support in South London (OASIS) UHR service (March 2013-April 2014). The diagnostic significance of DSM-5-APS was assessed with percent overall agreement, prevalence bias adjusted kappa, Bowker's test, Stuart-Maxwell test, residual analysis; the prognostic significance with Cox regression, Kaplan-Meier failure function, time-dependent area under the curve (AUC) and net benefits analysis. The impact of specific revisions of the DSM-5-APS was further tested. In 203 help-seeking individuals undergoing UHR assessment, the agreement between the DSM-5-APS and the CAARMS 12/2006 was only moderate (kappa 0.59). Among 142 nonpsychotic cases, those meeting DSM-5-APS criteria had a 5-fold probability (HR = 5.379) of developing psychosis compared to those not meeting DSM-5-APS criteria, with a 21-month cumulative risk of psychosis of 28.17% vs 6.49%, respectively. The DSM-5-APS prognostic accuracy was acceptable (AUC 0.76 at 24 months) and similar to the CAARMS 12/2006. The DSM-5-APS designation may be clinically useful to guide the provision of indicated interventions within a 7%-35% (2-year) range of psychosis risk. The removal of the criterion E or C of the DSM-5-APS may improve its prognostic performance and transdiagnostic value. The DSM-5-APS designation may be clinically useful in individuals accessing clinical services for psychosis prevention. © The Author 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com

Pärt, Arvo: Seven Magnificat Antiphons / Barry Witherden

Index Scriptorium Estoniae

Witherden, Barry

1996-01-01

Uuest heliplaadist "Pärt, Arvo: Seven Magnificat Antiphons. Magnificat. Summa; Tormis, Veljo: The Curse Upon Iron. Karelian Destiny. BBC Singers, Bo Holton". Collins Classics 1472-2 (61 minutes: DDD)

19 CFR 101.4 - Entry and clearance of vessels at Customs stations.

Science.gov (United States)

2010-04-01

... Jacksonville. Port St. Joe Panama City. Indiana Fort Wayne Indianapolis. Maine Bucksport Belfast. Coburn Gore.... Ely Duluth, MN-Superior, WI. Lancaster Noyes. Oak Island Warroad. Mississippi Biloxi Mobile, AL...

75 FR 39040 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Science.gov (United States)

2010-07-07

... Manistee Iron Works Machine Shop, 254 River St., Manistee, 10000477 Wayne County Rosedale Gardens Historic... Berry Morot Car Service Building, (Auto-Related Resources of St. Louis, Missouri [[Page 39041

78 FR 50445 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Science.gov (United States)

2013-08-19

... Evangelical Lutheran Church and Cemetery, MI 38 (Laird Township), Nisula, 13000665 Kent County Eastern Avenue... Contact Station, Bald Mountain Recreation Area Entrance Dr. (Orion Township), Auburn Hills, 13000670 Wayne...

Finding the minimal intervention needed for sustained mammography adherence.

Science.gov (United States)

Gierisch, Jennifer M; DeFrank, Jessica T; Bowling, J Michael; Rimer, Barbara K; Matuszewski, Jeanine M; Farrell, David; Skinner, Celette Sugg

2010-10-01

Regular adherence to mammography screening saves lives, yet few women receive regular mammograms. RCT. Participants were recruited through a state employee health plan. All were women aged 40-75 years and had recent mammograms prior to enrollment (n=3547). Data were collected from 2004 to 2009. Trial tested efficacy of a two-step adaptively-designed intervention to increase mammography adherence over 4 years. The first intervention step consisted of three reminder types: enhanced usual care reminders (EUCR); enhanced letter reminders (ELR); both delivered by mail, and automated telephone reminders (ATR). After delivery of reminders, women who became off-schedule in any of the 4 years received a second step of supplemental interventions. Three supplemental intervention arms contained priming letters and telephone counseling: barriers only (BarriCall); barriers plus positive consequences of getting mammograms (BarriConCall+); and barriers plus negative consequences of not getting mammograms (BarriConCall-). Average cumulative number of days non-adherent to mammography over 4 years based on annual screening guidelines (analyses conducted in 2009). All reminders performed equally well in reducing number of days of non-adherence. Women randomized to receive supplemental interventions had significantly fewer days of non-adherence compared to women who received EUCR (p=0.0003). BarrConCall+ and BarrConCall- conditions did not significantly differ in days non-adherent compared to women in the barriers-only condition (BarriCon). The minimal intervention needed for sustained mammography use is a combination of a reminder followed by a priming letter and barrier-specific telephone counseling for women who become off-schedule. Additional costs associated with supplemental interventions should be considered by organizations deciding which interventions to use. NCT01148875. Copyright © 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Stiilne seks / Marita Saar

Index Scriptorium Estoniae

Saar, Marita

2011-01-01

Raamatu "Discovering Your Couple Sexual Style" autorite Barry ja Emily McCarthy paaride seksuaalsestiili teooriast ning testist, mis aitab selgitada, millise seksuaalsestiili esindajad neljast te olete

the use of opto of pfa-based abrasive t based abrasive t micro se

African Journals Online (AJOL)

User

ENGINEERING,KOSZALIN UNIVERSITY OF TECHNOLOGY,. UFACTURING ..... standards. Table 2: General characteristics of grinding wheels used in the experiments. Technical ..... Academic Press, San Diego, 1998. [20] Wayne, R. O. Light ...

About the Director of EPA's National Health and Environmental Effects Research Laboratory (NHEERL)

Science.gov (United States)

Dr. Wayne Cascio serves as Acting Director for the National Health and Environmental Effects Research Laboratory (NHEERL) within the U.S. Environmental Protection Agency's Office of Research and Development (ORD).

77 FR 58900 - Mississippi Disaster #MS-00060

Science.gov (United States)

2012-09-24

... 09/11/2012. Incident: Hurricane Isaac. Incident Period: 08/26/2012 through 09/11/2012. DATES..., Newton, Pearl River, Perry, Pike, Smith, Stone, Walthall, Wayne, Wilkinson. The Interest Rates are...

Bringing holistic treatments to the attention of medicine: acupuncture as an effective poststroke rehabilitation tool.

Science.gov (United States)

Farmer, Cecilia

2015-04-01

This article reviews 3 studies that explore the effects of acupuncture on poststroke patients suffering from chronic stroke symptoms. The 3 studies selected strive to show how acupuncture can be a safe, noninvasive, and cost-effect rehabilitation tool useful in adjunct with traditional rehabilitation. Chou et al (2009), Hopwood et al (2008), and Wayne et al (2005) all studied acupuncture's effects on quality of life. Additionally, both Hopwood et al and Wayne et al studied acupuncture's effects on mobility and activities of daily living. While the frequency, duration, and length of the entire treatment varied by study, overall, the results of all 3 studies suggest that acupuncture increases quality of life and improves mobility and activities of daily living. © The Author(s) 2014.

Nobeli auhinna tõi Helicobacter pylori / Juhan Kaldre

Index Scriptorium Estoniae

Kaldre, Juhan

2005-01-01

Nobeli meditsiiniauhind määrati sel aastal Austraalia teadlastele Robin Warrenile ja Barry Marshallile, kes avastasid, et gastriit ning peptiline haavand tekib Helicobacter pylori infektsiooni tulemusena

Uue oskuse võlu / Helen Talalaev

Index Scriptorium Estoniae

Talalaev, Helen

2009-01-01

Tutvustatakse kirjastuse TEA väljaantud õppekomplekte: Tomalin, Barry. Westminster English. Tallinn : TEA Kirjastus, 2009 ; Mangus, Inga. Vene keele õpik : algajale ja taasalustajale. Tallinn : TEA Kirjastus, 2008

75 FR 33761 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

Science.gov (United States)

2010-06-15

..., National Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural... Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural Resources... directed to Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department...

76 FR 1595 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

Science.gov (United States)

2011-01-11

..., National Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural... Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural Resources... directed to Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division, Department...

ClimoBase: Rouse Canadian Surface Observations of Weather, Climate, and Hydrological Variables, 1984-1998, Version 1

Data.gov (United States)

National Aeronautics and Space Administration — ClimoBase is a collection of surface climate measurements collected in Northern Canada by Dr. Wayne Rouse between 1984 and 1998 in three locations: Churchill,...

75 FR 67973 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2010-11-04

... Individual), Joy V. Pareckattil, President/Director, Application Type: New NVO License. CJC Logistics Limited Liability Company dba CJC Container Line (NVO & OFF), 186 Alps Road, Wayne, NJ 07470. Officers: Oliver Rosca...

Uurimistöö-kompvek sugupuu-uurijale / Uno Schultz

Index Scriptorium Estoniae

Schultz, Uno, 1956-

2002-01-01

rets. rmt.: Maldonado, Sigrid Renate. Estonian experience and roots: ethnic Estonian genealogy with historical perspective, social influences and possible family history resources. Fort Wayne (USA) : AS WAS Publishing, 1996. 120 p.

Luminescence chronology of loess-paleosol sequences from Canterbury, South Island, New Zealand

International Nuclear Information System (INIS)

Berger, G.W.; Pillans, B.J.; Tonkin, P.J.

2001-01-01

The extensive Quaternary loess-paleosol deposits of South Island, New Zealand, represent one of the major proxy records of paleoclimatic changes in the Southern Hemisphere. We attempted to produce the first numeric chronology of these subaerial sequences in the Canterbury region by using thermoluminescence and infrared-stimulated luminescence dating methods. We examined five exposures: a 6 m thick section at Cust, north of Christchurch; two thicker (c. 14 m) sequences on Banks Peninsula (Barrys Bay and Onawe sites); farther south, a c. 12 m sequence in Timaru; and a c. 7 m sequence on the coast at the Normanby site near Timaru. Our results are largely based on single experiments per sample, and therefore provide imprecise ages for several of the older samples. The most satisfactory results are those from the youngest site (Cust), for which three samples were dated. Here, phases of maximum loess deposition are dated at 73 +/- 13 ka (basal loess-paleosol unit L3), 41 +/- 5 ka (basal L2), and 27 +/- 3 ka (basal L1). At Barrys Bay an age of 70 +/- 15 ka was obtained in the basal L1, and at Timaru two separate samples in the base of L1 also yielded ages of c. 70 ka, thus correlating the entire Cust loess sequence with the L1 loess unit at these two other study sites. Only at Barrys Bay were ages (c. 130-250 ka) in stratigraphic order obtained for older samples (units L2 and deeper). At the other sites, some samples in the sub-L1 units gave age reversals, and some (including the oldest sample at Barrys Bay) yielded poor precision (e.g., 20%). Units L2 at Timaru and Barrys Bay may correlate to all or part of MIS 6; however, the poor precision and some age reversals in other units at these sites and at Normanby and Onawe preclude any unambiguous correlations between sites or to the MIS time-scale. Nevertheless, in the absence of any prior numeric ages, these first results serve as a basis for more precise future dating of these units. Although these reconnaissance dating

Acute Toxicity of Tributyltins and Tributyltin Leachates from Marine Antibiofouling Paints.

Science.gov (United States)

1982-09-10

RO-0184 224 ACUTE TOXICITY OF TRIBUTYLTINS AND TRIBUTYLTIN i/I LEACHATES FROM MARINE ANTIBIOFOULING PAINTS(U) CALIFORNIA UNIV OAKLAND NAVAL...Classification) (U) ACUTE TOXICITY OF TRIBUTYLTINS AND TRIBUTYLTIN LEACHATES FROM MARINE ANTIBIOFOULING PAINTS 12, PERSO A UHR Laugin, Koy"., Linden, Olof and...xins causing acute toxicity or two amphipou species at concentrations as low as 10 g/L . Orchestia traskiana was exposed to bis ( tributyltin ) oxide

Inglitiibade kahin muusikas / Virve Normet

Index Scriptorium Estoniae

Normet, Virve, 1940-

2003-01-01

Maya Homburgeri (barokkviiul) kontserdist Pärnu raekojas 15. juulil ja tema ning Barry Guy' (kontrabass, basskitarr) ühisest kontserdist Eliisabeti kirikus 16. juulil David Oisrahhi festivali raames; esinejatest

76 FR 45570 - Consumer Advisory Committee

Science.gov (United States)

2011-07-29

... Consumer Action Network--Claude Stout Digital Policy Institute--Barry Umansky Hearing Loss Association of...--Debra Berlyn (Chairperson) Native Public Media--Dr. Traci Morris Rochester Institute of Technology--Raja...

Noor filoloog uuris karupoeg Puhhi ja Peeter Paani seiklusi / Anu Mõistlik

Index Scriptorium Estoniae

Mõistlik, Anu, 1980-

2003-01-01

Maarit Maimetsa bakalaureusetöö uurib kolme inglise lasteraamatu fantaasiaelemente: Lewis Carrolli "Alice imedemaal", James Matthew Barrie' "Lood Peeter Paanist" ja Alan Alexander Milne'i "Jutustus karupoeg Puhhist"

77 FR 16249 - Notice of Cancellation of Customs Broker Licenses

Science.gov (United States)

2012-03-20

... Dependable International Services 12574 New Orleans. and Transport, Inc.. Professional Customs Brokers, Inc.... Horizon Logistics, LLC 28432 Dallas. Sandra L. Smith 15266 Dallas. Barry E. Booth 09627 San Francisco...

75 FR 69639 - Procurement List; Proposed Addition

Science.gov (United States)

2010-11-15

... Graeber Street, March ARB, CA. NPA: ARC Riverside, Riverside, CA Contracting Activity: DEPT OF HOMELAND SECURITY, BUREAU OF CUSTOMS AND BORDER PROTECTION, WASHINGTON, DC. Barry S. Lineback, Director, Business...

76 FR 69793 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2011-11-09

... Michael Wayne Gilley William C. Miller Darrell Prather James Jaramillo One applicant, Robert J. Moore, Jr... federal government, state, or any political sub-division of the state. Jimmy Dale Johnson, II Wesley R...

Grow Plants the Organic Way: Give Them the Soil Microbes They Crave

Directory of Open Access Journals (Sweden)

Phil Mixter

2013-03-01

Full Text Available Review of: Teaming with Microbes: The Organic Gardener’s Guide to the Soil Food Web, revised ed.; Jeff Lowenfels and Wayne Lewis; (2010. Timber Press Inc., Portland, OR. 220 pages.

Steven Spielberg hädas Peeter Paaniga / Timo Diener

Index Scriptorium Estoniae

Diener, Timo

2004-01-01

Steven Spielbergi raskused J.M. Barrie "Peeter Paani" ekraniseerimisel, tulemuseks mängufilm "Hook" : Ameerika Ühendriigid 1991. Järgneb 16. aug. 2004, lk. 38 pealkirja all "Rahulolematu Steven Spielberg"

Reekviem unistusele : Venemaa-Gruusia sõja mõningatest julgeolekupoliitilistest mõjudest Eestile / Rein Tammsaar

Index Scriptorium Estoniae

Tammsaar, Rein

2008-01-01

Rahvusvahelisest ja rahvuslikust julgeolekust vastavalt Barri Buzani teooriale. Vajadusest tugevdada Eesti riiklikku julgeolekupoliitikat, suurendades ühiskondlikku sidusust erinevate kultuuride ning rahvuste vahel. Venemaa-Gruusia sõjast kui kaudsest õppetunnist Eestile

Inductive current startup in large tokamaks with expanding minor radius and RF assist

International Nuclear Information System (INIS)

Borowski, S.K.

1983-01-01

Auxiliary RF heating of electrons before and during the current rise phase of a large tokamak, such as the Fusion Engineering Device, is examined as a means of reducing both the initiation loop voltage and resistive flux expenditure during startup. Prior to current initiation, 1 to 2 MW of electron cyclotron resonance heating power at approx.90 GHz is used to create a small volume of high conductivity plasma (T/sub e/ approx. = 100 eV, n/sub e/ approx. = 10 19 m -3 ) near the upper hybrid resonance (UHR) region. This plasma conditioning permits a small radius (a 0 approx.< 0.4 m) current channel to be established with a relatively low initial loop voltage (approx.< 25 V as opposed to approx.100 V without RF assist). During the subsequent plasma expansion and current ramp phase, additional RF power is introduced to reduce volt-second consumption due to plasma resistance. To study the preheating phase, a near classical particle and energy transport model is developed to estimate the electron heating efficiency in a currentless toroidal plasma. The model assumes that preferential electron heating at the UHR leads to the formation of an ambipolar sheath potential between the neutral plasma and the conducting vacuum vessel and limiter

Initial results of a new generation dual source CT system using only an in-plane comb filter for ultra-high resolution temporal bone imaging

International Nuclear Information System (INIS)

Meyer, Mathias; Haubenreisser, Holger; Schoenberg, Stefan O.; Henzler, Thomas; Raupach, Rainer; Schmidt, Bernhard; Leidecker, Christianne; Allmendinger, Thomas; Flohr, Thomas; Lietzmann, Florian; Schad, Lothar R.

2015-01-01

To prospectively evaluate radiation dose and image quality of a third generation dual-source CT (DSCT) without z-axis filter behind the patient for temporal bone CT. Forty-five patients were either examined on a first, second, or third generation DSCT in an ultra-high-resolution (UHR) temporal bone-imaging mode. On the third generation DSCT system, the tighter focal spot of 0.2 mm 2 removesthe necessity for an additional z-axis-filter, leading to an improved z-axis radiation dose efficiency. Images of 0.4 mm were reconstructed using standard filtered-back-projection or iterative reconstruction (IR) technique for previous generations of DSCT and a novel IR algorithm for the third generation DSCT. Radiation dose and image quality were compared between the three DSCT systems. The statistically significantly highest subjective and objective image quality was evaluated for the third generation DSCT when compared to the first or second generation DSCT systems (all p < 0.05). Total effective dose was 63 %/39 % lower for the third generation examination as compared to the first and second generation DSCT. Temporal bone imaging without z-axis-UHR-filter and a novel third generation IR algorithm allows for significantly higher image quality while lowering effective dose when compared to the first two generations of DSCTs. (orig.)

Auroral kilometric radiation and magnetospheric substorm

International Nuclear Information System (INIS)

Morioka, Akira; Oya, Hiroshi

1980-01-01

The auroral kilometric radiation (AKR) and its relation to the development of the magnetospheric substorm have been studied based on the data obtained by JIKIKEN (EXOS-B) satellite. The occurrence of AKR is closely correlated to the intense UHR emission outside the plasmapause at the satellite position; the evidence clearly suggests that the development of the field aligned current system is associated with AKR generated at the upward current region and with the UHR emission at the downward current region. The drifting plasma due to the electric field that is generated in the magnetosphere at the moment of the magnetospheric substorm is derived from the frequency change of the plasma waves. The enhancement of the westward electric field in the duskside magnetosphere is detected simultaneously with the appearence of AKR. The altitude of the center of the AKR source region varies with intimate relation to the substorm activity suggesting that the generation of AKR is taking place in the region where the polar ionosphere and the magnetosphere are predominantly coupling through the precipitating or up going particles. From the fine structure of the dynamic spectra of AKR, it is suggested that the source of AKR might be closely related to the double layer type electric field along the magnetic field. (author)

Detailed Source-Specific Molecular Composition of Ambient Aerosol Organic Matter Using Ultrahigh Resolution Mass Spectrometry and 1H NMR

Directory of Open Access Journals (Sweden)

Amanda S. Willoughby

2016-06-01

Full Text Available Organic aerosols (OA are universally regarded as an important component of the atmosphere that have far-ranging impacts on climate forcing and human health. Many of these impacts are related to OA molecular characteristics. Despite the acknowledged importance, current uncertainties related to the source apportionment of molecular properties and environmental impacts make it difficult to confidently predict the net impacts of OA. Here we evaluate the specific molecular compounds as well as bulk structural properties of total suspended particulates in ambient OA collected from key emission sources (marine, biomass burning, and urban using ultrahigh resolution mass spectrometry (UHR-MS and proton nuclear magnetic resonance spectroscopy (1H NMR. UHR-MS and 1H NMR show that OA within each source is structurally diverse, and the molecular characteristics are described in detail. Principal component analysis (PCA revealed that (1 aromatic nitrogen species are distinguishing components for these biomass burning aerosols; (2 these urban aerosols are distinguished by having formulas with high O/C ratios and lesser aromatic and condensed aromatic formulas; and (3 these marine aerosols are distinguished by lipid-like compounds of likely marine biological origin. This study provides a unique qualitative approach for enhancing the chemical characterization of OA necessary for molecular source apportionment.

77 FR 75891 - Suspension of Community Eligibility

Science.gov (United States)

2012-12-26

... identifying the current participation status of a community can be obtained from FEMA's Community Status Book..., 1989, Reg; January 2, 2013, Susp. Fort Gay, Town of, Wayne 540202 April 29, 1975, ......do Do. County...

ClimoBase: Rouse Canadian Surface Observations of Weather, Climate, and Hydrological Variables, 1984-1998

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — ClimoBase is a collection of surface climate measurements collected in Northern Canada by Dr. Wayne Rouse between 1984 and 1998 in three locations: Churchill,...

Nonpathological and pathological narcissism: which self-reported characteristics are most problematic in adolescents?

Science.gov (United States)

Barry, Christopher T; Kauten, Rebecca L

2014-01-01

Prior research indicates that dimensions of adolescent narcissism differ in their associations with indicators of positive and negative psychological functioning (e.g., Barry, Frick, Adler, & Grafeman, 2007 ; Barry & Wallace, 2010 ). This study investigated correlates of 2 empirically derived factors of adolescent narcissism (i.e., pathological and nonpathological narcissism) from 2 measures thought to differ based on their inclusion of pathological versus nonpathological content. In a sample of 188 at-risk adolescents ages 16 to 18, pathological narcissism was associated with various indicators of maladjustment, including aggression, low self-esteem, internalizing problems, and poor perceived interpersonal relationships. On the other hand, nonpathological narcissism was positively associated with self-esteem and aggression but negatively associated with internalizing problems. The implications for the conceptualization of adolescent narcissism are discussed.

Mis kasu sellest kõigest on?

Index Scriptorium Estoniae

2004-01-01

Väljavõtteid mõttevahetusest 19. novembril 2004 toimunud rahvusvahelisel konverentsil "Kohtumine ristteel. Muuseum kui ühiskonna sõlmpunkt". Vestlusringis osalesid Barry Lord Torontost, Tomislav Shola Zagrebist ja Hanno Soans Eestist

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2006-01-01

Uutest heliplaatidest Barry White "Gold", Roseanne Cash "Black Cadillac", Satoshi Tomiie "Renaissance", Tiga "Sexor", Rec ja Rapresent "Isiklikult", Yo-Yo Ma "the Essential Yo-Yo Ma", Aqua Bassino "Rue de Paris"

Avastades muinasjuttude muinasjutte / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2005-01-01

Mängufilm Peeter Paani kuju loojast kirjanik James M. Barrie'st "Avastades Eikunagimaad" ("Finding Neverland") : režissöör Marc Forster : peaosas Johnny Depp : Ameerika Ühendriigid - Suurbritannia 2004

Johnny Depp moondus Londoni kirjanikuhärraks / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2005-01-01

Mängufilm Peeter Paani kuju loojast kirjanik James M. Barrie'st "Avastades Eikunagimaad" ("Finding Neverland") : režissöör Marc Forster : peaosas Johnny Depp : Ameerika Ühendriigid - Suurbritannia 2004

Reefer Madness: How Voters Responded to Medicinal Marijuana Initiatives in the 1998 State Elections

National Research Council Canada - National Science Library

Wood, Ryan

2001-01-01

.... In response to the perceived effects of illicit drugs, mandatory prison sentences have been lengthened for drug-related offenses, and General Barry McCafftey, former head of the Office of National...

Therapeutic efficacy of sulfadoxine-pyrimethamine in uncomplicated ...

African Journals Online (AJOL)

Therapeutic efficacy of sulfadoxine-pyrimethamine in uncomplicated Plasmodium falciparum malaria 3 years after introduction in Mpumalanga. Aaron Mabuza, John Govere, David Durrheim, Nicros Mangomezulu, Barry Bredenkamp, Karen Barnes, Brian Sharp ...

Adversity in childhood linked to elevated striatal dopamine function in adulthood

OpenAIRE

Egerton, A.; Valmaggia, L. R.; Howes, O. D.; Day, F.; Chaddock, C. A.; Allen, P.; Winton-Brown, T. T.; Bloomfield, M. A. P.; Bhattacharyya, S.; Chilcott, J.; Lappin, J. M.; Murray, R. M.; McGuire, P.

2016-01-01

Childhood adversity increases the risk of psychosis in adulthood. Theoretical and animal models suggest that this effect may be mediated by increased striatal dopamine neurotransmission. The primary objective of this study was to examine the relationship between adversity in childhood and striatal dopamine function in early adulthood. Secondary objectives were to compare exposure to childhood adversity and striatal dopamine function in young people at ultra high risk (UHR) of psychosis and he...

Presidential Green Chemistry Challenge: 1998 Academic Award (Trost)

Science.gov (United States)

Presidential Green Chemistry Challenge 1998 award winner Professor Barry M. Trost, developed the concept of atom economy: chemical reactions that do not waste atoms. This is a fundamental cornerstone of green chemistry.

Submerged Aquatic Vegetation observations from Coastal Alabama, Gulf of Mexico from 2002-07-23 to 2003-04-17 (NCEI Accession 0162519)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Mobile Bay National Estuary Program (MBNEP) contracted Barry A. Vittor and Associates, Inc. to conduct digital aerial image surveys of submerged aquatic...

75 FR 1269 - Vegetable Import Regulations; Modification of Potato Import Regulations; Correction

Science.gov (United States)

2010-01-11

...: Effective Date: January 11, 2010. FOR FURTHER INFORMATION CONTACT: Barry Broadbent or Gary D. Olson...-7440, or E-mail: [email protected] or GaryD.Olson@usda.gov . SUPPLEMENTARY INFORMATION: In FR...

Is clinical intervention in the ultra high risk phase effective? A intervenção clínica na fase de ultra alto risco é eficaz?

Directory of Open Access Journals (Sweden)

Philip McGuire

2011-10-01

Full Text Available Recent research suggests that early intervention in psychosis might improve the chances of recovery and may even be able to prevent the onset of psychotic disorders. Clinical intervention in subjects at ultra high risk (UHR of psychosis can have three different objectives. The first aim is to improve the 'prodromal' symptoms and problems that subjects usually present with. The second is to reduce the risk of the subsequent onset of frank psychosis. The third objective is to minimize the delay before the initiation of antipsychotic treatment in the subgroup of UHR subjects that go on to develop a first episode of psychosis. Both pharmacological and psychological interventions appear to be effective in reducing the severity of presenting symptoms in UHR subjects. Clinical trials of the impact of these interventions on the risk of subsequent transition to psychosis have been positive, but have involved small samples, and thus the issue of whether the effects persist in the long term remains to be determined. The monitoring of UHR subjects for the first signs of frank psychosis is an effective means of reducing the delay between the onset of the first episode and the start of antipsychotic treatment. Follow-up studies are required to test whether the reduction in this delay leads to an improved long term outcome. To date, the majority of the interventions that have been used in UHR subjects, such as case management, antipsychotic medication, and cognitive behavior therapy have previously been employed in patients with established psychosis. However, it is possible that treatments that are not normally used in patients with psychotic disorders may prove effective when applied at this stage.Estudos recentes sugerem que a intervenção precoce na psicose poderia melhorar as chances de recuperação e inclusive evitar o início de transtornos psicóticos. A intervenção cl��nica para indivíduos em ultra alto risco (UAR de psicose pode ter tr

77 FR 10606 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2012-02-22

... comments on-line. Privacy Act: Anyone may search the electronic form of all comments received into any of... (TX), Dale M. Cannon (OR), Jamie French (NC), Wayne H. Holt (UT), Billy R. Jefferies (WV), Carlos A...

77 FR 74456 - Notice of Proposed Changes to the National Handbook of Conservation Practices for the Natural...

Science.gov (United States)

2012-12-14

..., National Agricultural Engineer, Conservation Engineering Division, Department of Agriculture, Natural... may be directed to Wayne Bogovich, National Agricultural Engineer, Conservation Engineering Division...: Amendments for the Treatment of Agricultural Waste (Code 591), Building Envelope Improvement (Code 672...

Gap characteristics of southeastern Ohio second-growth forests

Science.gov (United States)

David M. Hix; Katherine K. Helfrich

2003-01-01

Transect sampling was used to assess the features of 30 gaps encountered in upland oak stands on the Wayne National Forest. Tip-ups caused the most canopy gaps (52 percent), two-thirds of which were small (

ORIGINAL ARTICLES The BEST study - a prospective study to ...

African Journals Online (AJOL)

business class versus economy class air travel as a cause of thrombosis. Barry F Jacobson .... replacement therapy (HRT) were also documented. Phlebotomy ..... relationship between flight class and the development of elevated D-dimers.

DA Masolo A Short History of African Philosophy, a Review pp165-171

African Journals Online (AJOL)

DA Masolo

Review of Barry Hallen's A Short History of African Philosophy, Second ... 2006, by African Philosophy: The Analytic Approach (Africa World Press). .... handling of culpability in witchcraft accusations as overlooking the obvious logical inference.

"Eesti Vabariigi julgeolekupoliitika alused" : Eesti julgeolekupoliitika suuna määraja? / Reelika Väljaru

Index Scriptorium Estoniae

Väljaru, Reelika

2005-01-01

Barry Buzani julgeolekupoliitika viiemõõtmelisest mudelist (militaarne, poliitiline, majanduslik, sotsiaalne ja keskkondlik), selle kajastumisest 2001. a. vastu võetud "Eesti Vabariigi julgeolekupoliitika alustes" ning Eesti välisministrite retoorikas aastatel 1998-2004

ORIGINAL ARTICLES

African Journals Online (AJOL)

PYRIMETHAMINE. I UNCOMPLICATED l'LASMODIUM FA LCIPARUM r IALARIA 3 YEARS AFTER. I TRODUCTION IN. T A:PUMALANGA f uon Mabuza, John Govere, David Durrheim, Nicros . ngomezulu, Barry Bredenkamp, Karen Barnes, Brian ...

A quiet leader unites researchers in drive for the next big machine

CERN Multimedia

Cho, Adrian

2006-01-01

"As head of the design team for the international linear collider, Barry Barish has physicists around the globe putting together. But can the governements ot the world afford their enormous particle smasher?" (2 pages)

Helicobakteri seljatasid tavalised arstid / Heidi-Ingrid Maaroos

Index Scriptorium Estoniae

Maaroos, Heidi-Ingrid, 1942-

2005-01-01

2005. aasta füsioloogia ja meditsiini Nobeli preemia omistati Austraalia arstidele Barry J. Marshallile ja Robin Warrenile gastriidi, mao- ja kaksteistsõrmikuhaavandi ning maovähi tekitaja Helicobacter pylori avastamise eest 1982. aastal

Telemehe salaelu / Jaan Ruus

Index Scriptorium Estoniae

Ruus, Jaan, 1938-2017

2008-01-01

George Clooney ja tema teine mängufilm "Ohtliku mehe pihtimused" ("Cofessions of a Dangerous Mind") : stsenarist teleprodutsent Chuck Barris'e memuaaride põhjal Charlie Kaufman : pearollis Sam Rockwell : Ameerika Ühendriigid - Saksamaa 2002

Advances in ontologies, proceedings of the Australasian ontology workshop, Melbourne, Australia

CSIR Research Space (South Africa)

Meyer, T (ed)

2009-12-01

Full Text Available Iannella Ken Kaneiwa C. Maria Keet Kevin Lee Laurent Lefort Constantine Mantratzis Lars Moench Deshendran Moodley Mehmet Orgun Maurice Pagnucco Debbie Richards Rolf Schwitter Murat Sensoy Barry Smith Markus Stumptner Boontawee...

Prokofiev: Romeo and Juliet - Suite N1 / Ivan March

Index Scriptorium Estoniae

March, Ivan

1990-01-01

Uuest heliplaadist "Prokofiev: Romeo and Juliet - Suite N1, Op.64b, N2, Op.64c. Philharmonia Orchestra, Barry Wordsworth" Collins Classics cassette 1116-4. CD. Võrreldud Neeme Järvi plaadistustega 1116-2

Luulud on lõbusamad kui reaalsus / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2006-01-01

George Clooney ja tema teine mängufilm "Ohtliku mehe pihtimused" ("Cofessions of a Dangerous Mind") : stsenarist teleprodutsent Chuck Barris'e memuaaride põhjal Charlie Kaufman : pearollis Sam Rockwell : Ameerika Ühendriigid - Saksamaa 2002

New thinking for the boiler room.

Science.gov (United States)

Rose, Wayne

2008-09-01

Wayne Rose, marketing manager at integrated plant room manufacturer Armstrong Integrated Systems, explains how increasing use of off-site manufacture, the latest 3D modelling technology, and advances in control technology, are revolutionising boiler room design and construction.

Societal trends : the aging baby boom and women's increased independence

Science.gov (United States)

1995-02-01

The document is one of five containing infrastructure inventories of facilities along the eastern U.S.-Canada border. This work, conducted by the Volpe Center and Wayne State University, draws upon previous studies and data collection efforts. These ...

Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis

Science.gov (United States)

van Donkersgoed, R. J. M.; Wunderink, L.; Nieboer, R.; Aleman, A.; Pijnenborg, G. H. M.

2015-01-01

Objective Treatment in the ultra-high risk stage for a psychotic episode is critical to the course of symptoms. Markers for the development of psychosis have been studied, to optimize the detection of people at risk of psychosis. One possible marker for the transition to psychosis is social cognition. To estimate effect sizes for social cognition based on a quantitative integration of the published evidence, we conducted a meta-analysis of social cognitive performance in people at ultra high risk (UHR). Methods A literature search (1970-July 2015) was performed in PubMed, PsychINFO, Medline, Embase, and ISI Web of Science, using the search terms ‘social cognition’, ‘theory of mind’, ‘emotion recognition’, ‘attributional style’, ‘social knowledge’, ‘social perception’, ‘empathy’, ‘at risk mental state’, ‘clinical high risk’, ‘psychosis prodrome’, and ‘ultra high risk’. The pooled effect size (Cohen’s D) and the effect sizes for each domain of social cognition were calculated. A random effects model with 95% confidence intervals was used. Results Seventeen studies were included in the analysis. The overall significant effect was of medium magnitude (d = 0.52, 95% Cl = 0.38–0.65). No moderator effects were found for age, gender and sample size. Sub-analyses demonstrated that individuals in the UHR phase show significant moderate deficits in affect recognition and affect discrimination in faces as well as in voices and in verbal Theory of Mind (TOM). Due to an insufficient amount of studies, we did not calculate an effect size for attributional bias and social perception/ knowledge. A majority of studies did not find a correlation between social cognition deficits and transition to psychosis, which may suggest that social cognition in general is not a useful marker for the development of psychosis. However some studies suggest the possible predictive value of verbal TOM and the recognition of specific emotions in faces

Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis.

Directory of Open Access Journals (Sweden)

R J M van Donkersgoed

Full Text Available Treatment in the ultra-high risk stage for a psychotic episode is critical to the course of symptoms. Markers for the development of psychosis have been studied, to optimize the detection of people at risk of psychosis. One possible marker for the transition to psychosis is social cognition. To estimate effect sizes for social cognition based on a quantitative integration of the published evidence, we conducted a meta-analysis of social cognitive performance in people at ultra high risk (UHR.A literature search (1970-July 2015 was performed in PubMed, PsychINFO, Medline, Embase, and ISI Web of Science, using the search terms 'social cognition', 'theory of mind', 'emotion recognition', 'attributional style', 'social knowledge', 'social perception', 'empathy', 'at risk mental state', 'clinical high risk', 'psychosis prodrome', and 'ultra high risk'. The pooled effect size (Cohen's D and the effect sizes for each domain of social cognition were calculated. A random effects model with 95% confidence intervals was used.Seventeen studies were included in the analysis. The overall significant effect was of medium magnitude (d = 0.52, 95% Cl = 0.38-0.65. No moderator effects were found for age, gender and sample size. Sub-analyses demonstrated that individuals in the UHR phase show significant moderate deficits in affect recognition and affect discrimination in faces as well as in voices and in verbal Theory of Mind (TOM. Due to an insufficient amount of studies, we did not calculate an effect size for attributional bias and social perception/ knowledge. A majority of studies did not find a correlation between social cognition deficits and transition to psychosis, which may suggest that social cognition in general is not a useful marker for the development of psychosis. However some studies suggest the possible predictive value of verbal TOM and the recognition of specific emotions in faces for the transition into psychosis. More research is needed on

Older patients’ use of technology for a post-discharge nutritional intervention

DEFF Research Database (Denmark)

Lindhardt, T.; Nielsen, M. H.

2017-01-01

Background Malnutrition is frequent in older people and a precursor for morbidity and hospitalisation; furthermore low intake and weight loss during and after hospitalisation is well-described. Such patients are often excluded from technology projects on account of lack of skills. This is a barri......'s preferences and views on barriers to successful intervention and use of technology in health care. This will guide the design of a future sufficiently powered study. Effect evaluation provided guidance for future sample size calculation.......-experimental controlled feasibility trial and embedded qualitative interviews. Participants: Older medical patients (mean age 79.4 years; women 66.7%) at nutritional risk and discharged to own home were included consecutively to first the control group (n = 18) and later the intervention group (n = 18). Nine intervention...

The Gain of Performance of Optical WDM Networks

Directory of Open Access Journals (Sweden)

Miroslav Bahleda

2008-01-01

Full Text Available We study the blocking probability and performance of single-fiber and multifiber optical networks with wavelength division multiplexing (WDM. We extend the well-known analytical blocking probability model by Barry and Humblet to the general model, which is proposed for both single-fiber and multifiber network paths with any kind of wavelength conversion (no, limited, or full wavelength conversion and for uniform and nonuniform link loads. We investigate the effect of the link load, wavelength conversion degree, and the number of wavelengths, fibers, and hops on blocking probability. We also extend the definition of the gain of wavelength conversion by Barry and Humblet to the gain of performance, which is fully general. Thanks to this definition and implementation of our model, we compare different WDM node architectures and present interesting results.

Language equity and assessment in South African education | Barry ...

African Journals Online (AJOL)

... assessment are closely linked and that the Language-in-Education policy and other additive bilingual initiatives have failed to address educational equity in South African schools. Despite the aspirations of politicians to move towards a policy of multiculturalism through the additive approach to bilingualism in education, ...

10 CFR Appendix A to Subpart A of... - Metropolitan Statistical Areas/Consolidated Metropolitan Statistical Areas With 1980 Populations...

Science.gov (United States)

2010-01-01

... Evansville-Henderson MSA IN-KY Fort Wayne MSA IN Fresno MSA CA Grand Rapids-Muskegon-Holland MSA MI... MSA LA New York-N. New Jersey-Long Island CMSA NY-NJ-CT-PA Norfolk-Virginia Beach-Newport News MSA VA...

COMPOSITION, MINERAL SAFETY INDEX, CALCIUM, ZINC AND ...

African Journals Online (AJOL)

Preferred Customer

This is the most patronized fast-food restaurant in Ado Ekiti, Nigeria. ..... Bertram, P. Fast Food Operations, Barrie and Jenkins Limited: London; 1975; p 100. 5. ... Varian Techtron Basic Atomic Absorption Spectroscopy- A Modern Introduction, ...

Determination of mechanical properties of materials used in WAY-30 test pavements.

Science.gov (United States)

2010-05-01

The US Route 30 bypass of Wooster, Ohio, in Wayne County, WAY-30, was constructed to demonstrate two types of : extended service pavements, a long-life Portland cement concrete (PCC) pavement on the eastbound lanes and an asphalt : concrete (AC...

A BIOINFORMATIC STRATEGY TO RAPIDLY CHARACTERIZE CDNA LIBRARIES

Science.gov (United States)

A Bioinformatic Strategy to Rapidly Characterize cDNA LibrariesG. Charles Ostermeier1, David J. Dix2 and Stephen A. Krawetz1.1Departments of Obstetrics and Gynecology, Center for Molecular Medicine and Genetics, & Institute for Scientific Computing, Wayne State Univer...

Cullin-5 and cullin-2 play a role in the development of ...

Indian Academy of Sciences (India)

2011-08-19

Aug 19, 2011 ... C-terminal domain of cullin protein binds to a RING-finger containing protein (viz. .... with a deficiency uncovering the gene. Flies were grown at. 25 ... nih.gov/ij/; Wayne Rasband, National Institute of Health,. 240. Journal of ...

Recruitment and Retention Strategies for Environmental Exposure Studies: Lessons from the Detroit Exposure and Aerosol Research Study

Science.gov (United States)

The Environmental Protection Agency’s Detroit Exposure and Aerosol Research Study (DEARS) was a complex 3-year personal exposure study. The six geographically defined areas in the Detroit (Wayne County), Michigan, area used as study locations are ethnically diverse; the majority ...

77 FR 58903 - Mississippi Disaster Number MS-00059

Science.gov (United States)

2012-09-24

..., Madison, Newton, Perry, Rankin, Simpson, Wayne, Yazoo. Alabama: Choctaw. Louisiana: Concordia, East Carroll, East Feliciana, Madison, Saint Helena, Tangipahoa, Tensas, West Feliciana. All other information... and 59008) James E. Rivera, Associate Administrator for Disaster Assistance. [FR Doc. 2012-23408 Filed...

Availability of EPA Tools and Resources to Increase Awareness of the Cardiovascular Health Effects of Air Pollution

Science.gov (United States)

On November 14, 2017 Dr. Wayne Cascio, Acting Director will present a webinar titled, “Availability of EPA Tools and Resources to Increase Awareness of the Cardiovascular Health Effects of Air Pollution” to HHS’ Million Hearts Federal Partner’s Monthly Cal...

PUBLIC COMMENT ON THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2018 FEDERAL PHYSICAL ACITIVTY GUIDELINES

Science.gov (United States)

Title: Public Comment on Department of Health and Human Services (DHHS) 2018 Physical Activity Guidelines Author: Wayne E. Cascio, Director, Environmental Public Health Division, US EPA Abstract: In the 2008 Physical Activity Guidelines, the effects of air pollution and advers...

Genomics Encyclopedia of Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB): a resource for microsymbiont genomes (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

Energy Technology Data Exchange (ETDEWEB)

Reeve, Wayne [Murdoch University

2013-03-01

Wayne Reeve of Murdoch University on "Genomics Encyclopedia of Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB): a resource for microsymbiont genomes" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

76 FR 59166 - Navistar Truck Development and Technology Center, a Subsidiary of Navistar International...

Science.gov (United States)

2011-09-23

... Development and Technology Center, a Subsidiary of Navistar International Corporation Truck Division, Fort... International Corporation, Truck Division, Fort Wayne, Indiana (subject firm). The negative determination was... is a headcount reduction across the nation, made possible by the Global Outsourcing. * * * '' The...

Contribution a l'etude des plantes alimentaires mineures dans la ...

African Journals Online (AJOL)

Contribution a l'etude des plantes alimentaires mineures dans la prefecture de Dankpen (Togo). AB Kebenzikato, S Akpavi, K Batawila, K Wala, M Dourma, K Kossi-Titrikou, KS Amouzou, I Butare, H Dantsey-Barry, K Akpagana ...

Ameerika ja Nõukogude Liidu kunstivahetus sulaajal: uhketest avamistest rutakate taandumisteni = Soviet-American art exchanges during the thaw: from bold openings to hasty retreats / Simo Mikkonen

Index Scriptorium Estoniae

Mikkonen, Simo, 1978-

2013-01-01

Nõukogude Liidu valmidusest kultuurivahetuseks, vahetuste iseloomust ja nendega kaasnenud piirangutest. Ameerika ja Nõukogude kunstiprofessionaalide koostööst vahetusprojektide korraldamisel ning nende tegutsemisvabaduse määrast poliitilise surve all. Alfred Barri rollist näitustevahetuse elluviimisel.

A Basis for an Assembly Processor for COTS-Based Systems (APCS)

National Research Council Canada - National Science Library

Carney, David

2003-01-01

.... The framework is based on Barry Boehm's familiar spiral development process. However, it is primarily intended for projects that make significant use of commercial components and other preexisting software as elements of the system to be fielded...

Plasma heating via electron Bernstein wave heating using ordinary and extraodinary mode

Directory of Open Access Journals (Sweden)

A. Parvazian

2008-03-01

Full Text Available Magnetically confined plasma can be heated with high power microwave sources. In spherical torus the electron plasma frequency exeeds the electron cyclotron frequency (EC and, as a consequence, electromagnetic waves at fundamental and low harmonic EC cannot propagate within the plasma. In contrast, electron Bernstein waves (EBWs readily propagate in spherical torus plasma and are absorbed strongly at the electron cyclotron resonances. In order to proagate EBWs beyond the upper hybrid resonance (UHR, that surrounds the plasma, the EBWs must convert via one of two processes to either ordinary (O-mode or extraordinary (X-mode electromagnetic waves. O-mode and X-mode electromagnetic waves lunched at the plasma edge can convert to the electron Bernstein waves (EBWs which can propagate without and cut-off into the core of the plasma and damp on electrons. Since the electron Bernstein wave (EBW has no cut-off limits, it is well suited to heat an over-dense plasma by resonant absorption. An important problem is to calculate mode conversion coefficient that is very sensitive to density. Mode conversion coefficient depends on Budden parameter ( ñ and density scale length (Ln in upper hybrid resonance (UHR. In Mega Ampere Spherical Tokamak (MAST, the optimized conversion efficiency approached 72.5% when Ln was 4.94 cm and the magnetic field was 0.475 Tesla in the core of the plasma.

Epigenetic variability in conversion to psychosis: novel findings from an innovative longitudinal methylomic analysis.

Science.gov (United States)

Kebir, Oussama; Chaumette, Boris; Krebs, Marie-Odile

2018-04-26

Conversion to psychosis is a longitudinal process during which several epigenetic changes have been described. We tested the hypothesis that epigenetic variability in the methylomes of ultra-high risk (UHR) individuals may contribute to the risk of conversion. We studied a longitudinal cohort of UHR individuals (n = 39) and compared two groups (converters, n = 14 vs. non-converters, n = 25). A longitudinal methylomic study was conducted using Infinium HumanMethylation450 BeadChip covering half a million cytosine-phosphate-guanine (CpG) sites across the human genome from whole-blood samples. We used two statistical methods to investigate the variability of methylation probes. (i) The search for longitudinal variable methylation probes (VMPs) based on median comparisons identified two VMPs in converters only. The first CpG was located in the MACROD2 gene and the second CpG was in an intergenic region at 8q24.21. (ii) The detection of outliers using variance analysis related to private epimutations identified a dozen CpGs in converters only and highlighted two genes (RAC1 and SPHK1) from the sphingolipid signaling pathway. Our study is the first to support increased methylome variability during conversion to psychosis. We speculate that stochastic factors could increase DNA methylation variability and have a role in the complex pathophysiology of conversion to psychosis as well as in other psychiatric diseases.

African Zoology - Vol 41, No 2 (2006)

African Journals Online (AJOL)

Thermoregulation under semi-natural conditions in speckled mousebirds: the role of communal roosting · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Andrew E. McKechnie, Gerhard Körtner, Barry G. Lovegrove, 155-163.

I Remember Highlander

Science.gov (United States)

Williams-Hawkins, Maria

2016-01-01

"I Remember Highlander" reflects on the life choices of Marion Barry and Herman Henning Jr., fraternity brothers who sought the same goal but took different paths. The essay examines cultural and family situations that shaped lives and decisions.

78 FR 43854 - Designation for the Muncie, IN; Fremont, NE; Annapolis, MD; and West Lafayette, IN Areas...

Science.gov (United States)

2013-07-22

..., Hendricks, Henry, Jay, Johnson, Madison, Marion, Monroe, Morgan, Randolph, Rush, Shelby, Union, and Wayne Counties. In Ohio Darke County. This designation action to provide official services in these specified... Cooperative elevator located in Shelby, Polk County, Nebraska. Correction In the Federal Register Notice...

Determination of mechanical properties of materials used in WAY-30 test pavements : executive summary report.

Science.gov (United States)

2010-05-01

ODOT selected a relocation of US Route 30 near Wooster : in Wayne County, the WAY-30 project, as the site for : testing long life pavements. The eastbound lanes were : constructed with a long-life Portland Cement Concrete : (PCC) pavement, and the we...

Treatment of Sleep Apnea in Patients with Cervical Spinal Cord Injury

Science.gov (United States)

2017-08-01

Badr, M.D. CONTRACTING ORGANIZATION: Wayne State University Detroit, MI 48201 REPORT DATE: August 2017 TYPE OF REPORT: Annual PREPARED FOR...measurements of air pressure and airflow. Our methods will allow us to quantify ventilation, measure the severity of inspiratory flow limitation

Assessment of DAPG-producing Pseudomonas fluorescens for management of Meloidogyne incognita and Fusarium oxysporum on watermelon

Science.gov (United States)

Pseudomonas fluorescens isolates Clinto 1R, Wayne 1R and Wood 1R, which produce the antibiotic 2,4-diacetylphloroglucinol (DAPG), can suppress soilborne diseases and promote plant growth. Consequently, these beneficial bacterial isolates were tested on watermelon plants for suppression of Meloidogy...

Anmerkungen zu Goethe : eine psychoanalytische Untersuchung über Goethe als Repräsentant deutscher Kultur

NARCIS (Netherlands)

Kaus, Rainer J.

1994-01-01

De oorspronkelijke aanleiding tot dit onderzoek was de invloedrijke psychoanalytische studie in twee delen van K.R. Eissler, Goethe: A Psychoanalytic Study 1775-1786, oorspronkelijk verschenen in de Verenigde Staten (Detroit: Wayne State UP, 1963), in Duitse vertaling bij uitgeverij Stroemfeld/Roter

A New Institutionalism? The English School as International Sociological Theory

DEFF Research Database (Denmark)

Schouenborg, Laust

2011-01-01

In this article I engage with the theoretical opening provided by Barry Buzan’s From International to World Society? I present an argument for five functional categories, which should be able to encompass all the institutions identified by English School scholars throughout history. Their introdu......In this article I engage with the theoretical opening provided by Barry Buzan’s From International to World Society? I present an argument for five functional categories, which should be able to encompass all the institutions identified by English School scholars throughout history....... Their introduction should point the way towards a sounder analytical framework for the study of what Buzan believes should be the new subject of the discipline of International Relations (IR). This subject is defined as second-order societies, meaning societies ‘where the members are not individual human beings...

Dynamics of partial differential equations

CERN Document Server

Wayne, C Eugene

2015-01-01

This book contains two review articles on the dynamics of partial differential equations that deal with closely related topics but can be read independently. Wayne reviews recent results on the global dynamics of the two-dimensional Navier-Stokes equations. This system exhibits stable vortex solutions: the topic of Wayne's contribution is how solutions that start from arbitrary initial conditions evolve towards stable vortices. Weinstein considers the dynamics of localized states in nonlinear Schrodinger and Gross-Pitaevskii equations that describe many optical and quantum systems. In this contribution, Weinstein reviews recent bifurcations results of solitary waves, their linear and nonlinear stability properties, and results about radiation damping where waves lose energy through radiation.   The articles, written independently, are combined into one volume to showcase the tools of dynamical systems theory at work in explaining qualitative phenomena associated with two classes of partial differential equ...

GLOBAL JOURNAL OF SOCIAL SCIENCES VOL 8, NO

African Journals Online (AJOL)

Ada

KEYWORDS: Dam/Irrigation projects; climate change; trend modeling; and rainfall trends. 1. ... caused a change in the world's climate (Obasi,. 1992; Barry and ... The dry effect of the cT is .... cloud formed under this circumstance is very high.

Navier-Stokes

NARCIS (Netherlands)

Koren, B.

2013-01-01

De Navier-Stokes-vergelijkingen behoren tot de meest gebruikte vergelijkingen voor de berekening van gas- en vloeistofstromingen. Op de Vakantiecursus 2013 van het Platform Wiskunde Nederland vertelt Barry Koren over de Navier-Stokes-vergelijkingen, over stromingsleer en over openstaande

The effect of thermo-ammoniation on the nutritive value of maize ...

African Journals Online (AJOL)

nutritive value of maize residues. L.D. Snyman,* D. Aartsma, N. Barrie &. C. Engelbrecht. Department of Agricultural Development, Highveld Region,. Potchefstroom,2520. Republic of South Africa. * Authorto whom correspondenceshould be addressedat: OnderstepoortVeterinaryInstitute.Private Bag X5, Onderstepoort,.

Relationships between the school-level and classroom-level ...

African Journals Online (AJOL)

aspirations had significantly less interest in music than did students with high- ..... I have sufficient knowledge about OBE to deal with OBE-related issues in my teaching. ..... Barry Fraser is Professor and Director of the Science and Mathematics ...

Outcome of radioiodine therapy without, on or 3 days off carbimazole: a prospective interventional three-group comparison

Energy Technology Data Exchange (ETDEWEB)

Walter, Martin A. [University Hospital, Institute of Nuclear Medicine, Basel (Switzerland); University Hospital Basel, Division of Endocrinology, Diabetology and Clinical Nutrition, Basel (Switzerland); Christ-Crain, Mirjam; Mueller, Beat [University Hospital Basel, Division of Endocrinology, Diabetology and Clinical Nutrition, Basel (Switzerland); Schindler, Christian [University Hospital Basel, Institute of Social and Preventive Medicine, Basel (Switzerland); Mueller-Brand, Jan [University Hospital, Institute of Nuclear Medicine, Basel (Switzerland)

2006-06-15

Carbimazole ameliorates hyperthyroidism but reduces radioiodine uptake and adversely affects the outcome of simultaneous radioiodine therapy. We explored whether withdrawal of carbimazole for 3 days can restore the outcome of radioiodine treatment without concurrent exacerbation of hyperthyroidism. By generating three groups with comparable radioiodine uptake, we also investigated whether the effect of carbimazole depends on the radioiodine uptake. Stratified by a radioiodine uptake >30%, 227 consecutive adult patients were prospectively assigned to radioiodine therapy (target dose 200 Gy) without, on or 3 days off carbimazole. Patients were clinically (Crooks-Wayne score) and biochemically (T{sub 3}, fT{sub 4}, TSH) followed up after 3, 6 and 12 months. Primary endpoint was outcome 12 months after radioiodine therapy. A total of 207 patients completed follow-up (toxic nodular goitre, n=117; Graves' disease, n=90). The overall success rate was 71.5%. Patients without and 3 days off carbimazole had similar biochemical (81.4% and 83.3%, respectively; p=0.82) and clinical outcomes [median (range) Crooks-Wayne score 0 (0-16) and 1 (0-10), respectively; p=0.73], which were both higher than in patients on carbimazole [42.6%, p<0.001; Crooks-Wayne score 3 (0-30), p<0.03]. Time to achieve cure was delayed on carbimazole. No changes in thyroid hormone levels occurred after 3 days' discontinuation of carbimazole. Logistic regression revealed that all observed cure rates were independent of entity, sex, age, thyroid volume, radioiodine uptake, radioiodine half-life, fT{sub 4}, T{sub 3} and TSH. (orig.)

Chloroformate derivatization for tracing the fate of Amino acids in cells and tissues by multiple stable isotope resolved metabolomics (mSIRM).

Science.gov (United States)

Yang, Ye; Fan, Teresa W-M; Lane, Andrew N; Higashi, Richard M

2017-07-11

Amino acids have crucial roles in central metabolism, both anabolic and catabolic. To elucidate these roles, steady-state concentrations of amino acids alone are insufficient, as each amino acid participates in multiple pathways and functions in a complex network, which can also be compartmentalized. Stable Isotope-Resolved Metabolomics (SIRM) is an approach that uses atom-resolved tracking of metabolites through biochemical transformations in cells, tissues, or whole organisms. Using different elemental stable isotopes to label multiple metabolite precursors makes it possible to resolve simultaneously the utilization of these precursors in a single experiment. Conversely, a single precursor labeled with two (or more) different elemental isotopes can trace the allocation of e.g. C and N atoms through the network. Such dual-label experiments however challenge the resolution of conventional mass spectrometers, which must distinguish the neutron mass differences among different elemental isotopes. This requires ultrahigh resolution Fourier transform mass spectrometry (UHR-FTMS). When combined with direct infusion nano-electrospray ion source (nano-ESI), UHR-FTMS can provide rapid, global, and quantitative analysis of all possible mass isotopologues of metabolites. Unfortunately, very low mass polar metabolites such as amino acids can be difficult to analyze by current models of UHR-FTMS, plus the high salt content present in typical cell or tissue polar extracts may cause unacceptable ion suppression for sources such as nano-ESI. Here we describe a modified method of ethyl chloroformate (ECF) derivatization of amino acids to enable rapid quantitative analysis of stable isotope labeled amino acids using nano-ESI UHR-FTMS. This method showed excellent linearity with quantifiable limits in the low nanomolar range represented in microgram quantities of biological specimens, which results in extracts with total analyte abundances in the low to sub-femtomole range. We have

Traumatic Rupture of the Posterior Urethra. Analysis of 87 Cases at ...

African Journals Online (AJOL)

Traumatic Rupture of the Posterior Urethra. Analysis of 87 Cases at the Conakry University Hospital. A B Diallo, M Barry, I Bah, A T Diallo, O R Bah, A Toure, S Balde, K B Sow, S Guirassay, M B Diallo ...

WYNBERG MILITARY BASE AND THE ARMY OFFICERS' CLUB

African Journals Online (AJOL)

ished; a few of those built in the latter half of the nineteenth century still remain scattered in- ... Scientia Militaria, South African Journal of Military Studies, Vol 19, Nr 1, 1989. ..... Molo, J.Military Fashion,Barrie and Jenkins, London, 1972. 15.

The effect of different detanninfication effects on the tannins found in ...

African Journals Online (AJOL)

200604877

2013-12-18

Dec 18, 2013 ... Int. J. Crude Drug Res. 23, 87-90. Barry, T.N. ... Analysis of condensed tannins using Acidified Vanillin. J. Sci. Food. Agr. 29, 788-794. .... Interactions among tannins, supplementation and polyethylene glycol in goats given oak ...

Initial Spare Parts of the A400M Aircraft

Science.gov (United States)

2012-03-08

inventory. Therefore, a balance has to be sought between inventory cost and customer service ( Heizer & Render , 2010:500-501). Nevertheless, spare part... Heizer , Jay H. and Barry Render . Principles of Operations Management. Boston: Pearson Education, 2011. Heuninckx, Baudouin. “Availability

Nobeli meditsiinipreemia teema puudutab Eestit / Aleksei Günter

Index Scriptorium Estoniae

Günter, Aleksei, 1979-

2005-01-01

Tänavuse Nobeli meditsiinipreemia laureaatideks osutusid Austraalia teadlased Barry J. Marshall ja J. Robin Warren, kelle avastus ja uurimistöö tõi murrangu maohaiguste ravipõhimõtetesse, mis on ka Eesti jaoks suure tähtsusega. Lisa: Helicobacter pylori

'Daughteronomy': Akachi Adimora- Ezeigbo, domestic amazons and ...

African Journals Online (AJOL)

sexual inequality” (Barry 2002: 122).1 This pursuit was to a great extent a critical ..... odds against women in a typical Nigerian workplace is what some of their male ... students who are “rather more vulnerable” to sexual harassment at school.

Ecologische en natuurbeschermingsrechtelijke aspecten van windturbines op land

NARCIS (Netherlands)

Winkelman, J.E.; Kistenkas, F.H.; Epe, M.J.

2008-01-01

Uit dit literatuuronderzoek komt naar voren dat windturbines aanzienlijke effecten kunnen hebben op vleermuizen en vogels in de zin van aantallen aanvaringsslachtoffers, mate van verstoring en/of barrièrewerking. Omdat vleermuizen en vogels onder andere bescherming genieten vanwege de

ISSN 2073-9990 East Cent. Afr. J. 0 East Cent. Afr. J. 0 East Cent ...

African Journals Online (AJOL)

dell

2014-04-01

Apr 1, 2014 ... difference at different times of the day or in different phases of the ... and standard deviation were calculated, including comparisons for sex and age. .... AchavaL M, Forsythe I, Barry PW, brain and respiratory cilia: effect of.

77 FR 68737 - Procurement List, Proposed Deletions

Science.gov (United States)

2012-11-16

...: Janitorial/Custodial, Defense Logistics Agency: Point Pleasant Depot, Defense National Stockpile Zone, 2601.... Contracting Activity: Defense Logistics Agency Support Services-- DSS, Fort Belvoir, VA. Service Type/Location.... Contracting Activity: Defense Commissary Agency (DECA), Fort Lee, VA. Barry S. Lineback, Director, Business...

75 FR 8896 - Notice of Funding Availability (NOFA) for Loan Guarantees Under Section 538 Guaranteed Rural...

Science.gov (United States)

2010-02-26

..., (706) 546-2164, TDD (706) 546-2034, Wayne Rogers. Hawaii State Office, (Services all Hawaii, American Samoa Guam, and Western Pacific), Room 311, Federal Building, 154 Waianuenue Avenue, Hilo, HI 96720...-7772, Tammy Repine. Western Pacific Territories, Served by Hawaii State Office. West Virginia State...

Studies in Intelligence. Volume 57, Number 2 (June 2013)

Science.gov (United States)

2013-06-01

The goods they steal are usually sold to black mar- ket operators. The Edelweiss insig- nia is seen frequently in Germany, and it has become...and Execute Intelligence Collection in Complex Environments by Wayne Michael Hall and Gary Citrenbaum. (Praeger) 505 pp., endnotes, bibliography

75 FR 10658 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

Science.gov (United States)

2010-03-09

... structure. DATES: This AD becomes effective April 13, 2010. The Director of the Federal Register approved... CONTACT: Wayne Lockett, Aerospace Engineer, Airframe Branch, ANM-120S, FAA, Seattle Aircraft Certification... on pressurized fuselage structure. Compliance (f) You are responsible for having the actions required...

78 FR 26391 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Science.gov (United States)

2013-05-06

... Architecture MPS), 100 Casey Key Rd., Nokomis, 13000320 MICHIGAN Genesee County United States Post Office, 600 Church St., Flint, 13000321 Wayne County United States Immigration Station, 333 Mount Elliott St... properties under the National Register criteria for evaluation. Comments may be forwarded by United States...

76 FR 55541 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia: Kentucky; Ohio...

Science.gov (United States)

2011-09-07

... Cabell and Wayne Counties in their entireties and a portion of Mason County (Graham Tax District) in West... reasonable further progress (RFP) plan, contingency measures, and other planning State Implementation Plan... Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S...

Undervisning af tosprogede elever

DEFF Research Database (Denmark)

Horst, Christian

2003-01-01

Artiklen fremdrager hovedresultaterne fra Virginia P. Collier's og Wayne P. Thomas's længdeundersøgelser af tosprogede elever i USA, som formentlig er de mest omfattende undersøgelser af undervisningen af tosprogede elever overhovedet. Resultaterne diskuteres i relation til udviklingen af en...

Development of microsatellite markers for Helopeltis theivora ...

African Journals Online (AJOL)

USER

2010-07-12

Jul 12, 2010 ... are highly polymorphic, neutral and show Mendelian inheritance, they therefore represent one of the most powerful tools for population genetic studies (Bruford and. Wayne, 1993). Microsatellites have also been analysed extensively in Drosophila melanogaster (Bachtrog et al.,. 1999), Drosophila simulans ...

77 FR 47670 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-08-09

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,151; TA-W-75,151A] Amended... Reliability Center, A Subsidiary of Navistar International Corporation, Truck Division, Including All On-Site... Reliability Center, a Subsidiary of Navistar International Corporation, Truck Division, 3033 Wayne Trace, Fort...

75 FR 19348 - Notice of Funding Availability (NOFA): Section 515 Rural Rental Housing Program for New...

Science.gov (United States)

2010-04-14

..., TDD (706) 546-2034, Wayne Rogers. Hawaii State Office, (Services all Hawaii, American Samoa Guam, and Western Pacific), Room 311, Federal Building, 154 Waianuenue Avenue, Hilo, HI 96720, (808) 933-8305, TDD... McKitrick. Western Pacific Territories, Served by Hawaii State Office. West Virginia State Office, Federal...

The Path of the Blind Watchmaker: A Model of Evolution

Science.gov (United States)

2011-04-06

our countermeasures. Viruses evolve into new strains such that the antibodies produced due to vaccines are ineffective. Bacteria evolve into new...Maddison, Katja- Sabine Schulz, & Wayne P. Maddison. (2007). The Tree of Life Web Project. Zootaxa, 1668, 19-40. [42] Matt Ridley. (2000). The search for

ARC Researchers at 2016 SAE Congress

Science.gov (United States)

. Henein, Wayne State University 1:30 pm 2016-01-0310 An Engine Thermal Management System Design for ; Zissimos Mourelatos, Oakland University Session PFL370; Room 360 Holistic Session on Fuel Consumption and , powertrain, and supporting electromechanical subsystems related to energy management. 4:30 pm 2016-01-1239

Test at Ford

NARCIS (Netherlands)

Davidsson, A.; Rhijn, G. van

2002-01-01

This report describes the test of the Ergotool module of the E/S tool and the participative procedure performed at the Final Assembly shop of the Wayne plant at Ford Motor Company, Michigan, USA. Three stations were selected. videotaped, measured, and evaluated according to the Ergotool and

Critical Curriculum Studies: Education, Consciousness, and the Politics of Knowing. Critical Social Thought

Science.gov (United States)

Au, Wayne

2011-01-01

"Critical Curriculum Studies" offers a novel framework for thinking about how curriculum relates to students' understanding of the world around them. Wayne Au brings together curriculum theory, critical educational studies, and feminist standpoint theory with practical examples of teaching for social justice to argue for a transformative…

Sammelrezension: Neue Publikationen zum Horrorfilm

OpenAIRE

Stiasny, Philipp

2005-01-01

Reynold Humphries: The American Horror Film. An IntroductionPeter Hutchings: The Horror FilmJoseph Maddrey: Nightmares in Red, White and Blue. The Evolution of the American Horror FilmBarry Keith Grant, Christopher Sharret (Hg.): Planks of Reason. Essays on the Horror Film

Cultural Identity and Regional Security in the Western Balkans

Science.gov (United States)

2013-06-13

collectivist goals of humanitarian intervention.”45 Certainly, one of the most prominent representatives of this school is Barry Buzan. He has...sovereignty of the Hungarian monarch in exchange of holding some degree of local political autonomy inside Croatia. Although, some recent...

76 FR 35997 - Onions Grown in Certain Designated Counties in Idaho, and Malheur County, OR; Modification of...

Science.gov (United States)

2011-06-21

... INFORMATION CONTACT: Barry Broadbent or Gary D. Olson, Northwest Marketing Field Office, Marketing [email protected] . SUPPLEMENTARY INFORMATION: This rule is issued under Marketing Agreement No. 130... used to collect information under this marketing order. Once the modified forms are approved, they will...

5282 Volume 11 No. 6 October 2011 SIZE REDUCTIONOF FOOD ...

African Journals Online (AJOL)

SDLRC4

2011-10-06

Oct 6, 2011 ... In addition to the audit,36 ... principle of attrition using a disc attrition mill [1]. ... Food safety is defined as an assurance that food will not cause harm to ..... Barrie D The provision of food and catering services in hospitals.

· ORIGINAL ARTICLES

African Journals Online (AJOL)

J"fPUMALANGA f uon Mabuza, John Govere, David Durrheim, Nicros. ~. ngomezulu, Barry Bredenkamp, Karen Bames, Brian Sharp bjectives. To assess therapeutic efficacy of sulfadoxine- yrimethamine (SP) in treatment of uncomplicated lasmodium falciparum malaria 3 years after introduction in lpumalanga, South Africa.

DCS Terrain for Wayne County GA MapMod08

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix M: Data Capture Standards, describes the digital topographic data that was used to create...

DIGITAL FLOOD INSURANCE RATE MAP DATABASE, WAYNE COUNTY, USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

Eschenmoser Approach to Vitamin B

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 7. Eschenmoser Approach to Vitamin B12 by A/D Strategy: An Unexpected Journey. G Wayne Craig. General Article Volume 19 Issue 7 July 2014 pp 624-640. Fulltext. Click here to view fulltext PDF. Permanent link:

Proposal for a Wellness Clinician/Research Specialization for the Existing Degree Program, Master of Education in Physical Education.

Science.gov (United States)

Cardinal, Bradley J.; And Others

Consistent with the Year 2000 National Health Promotion and Disease Prevention Objectives, this paper presents a proposal for a Wellness Clinician/Research specialization within the existing Master of Education in Physical Education degree program offered by the Division of Health, Physical Education, and Recreation at Wayne State University…

ACHP | News | President Announces Appointments to Advisory Council on

Science.gov (United States)

," said ACHP Chairman Milford Wayne Donaldson, FAIA. "Their respective expertise will be of Side Waterfront-Hudson River Park Plan in New York City, the Charles River Basin Plan for the we welcome our new members, we also thank the two appointees who will be leaving the ACHP after

77 FR 2603 - Public Notice for Waiver of Aeronautical Land-Use Assurance; Willow Run Airport; Detroit, MI

Science.gov (United States)

2012-01-18

... property for sale. The land consists of portions of the original airport parcels. These parcels were... (Wayne County Airport Authority) from the U.S. Government, General Services Administration without... with section 47107(h) of title 49, United States Code, this notice is required to be published in the...

75 FR 62048 - Proposed Flood Elevation Determinations

Science.gov (United States)

2010-10-07

... Brown Street, Runnells, IA 50237. Unincorporated Areas of Polk County Maps are available for inspection... Sugar Creek Approximately 250 feet None +1080 Township of Wayne. downstream of U.S. Route 322... Addison. upstream of Robert Brown Road. Approximately 1.25 mile None +1386 upstream of Robert Brown Road...

Homelessness as the Unforgiving Minute of the Present: The Rhetorical Tenses of Democratic Citizenship

Science.gov (United States)

Loehwing, Melanie

2010-01-01

Popular discourse and advocacy efforts characterize homelessness as a social problem bound by the present-centered concerns of physical affliction and material deprivation. Wayne Powers's documentary film "Reversal of Fortune" exemplifies this tendency by performing a "social experiment" to investigate how giving a homeless man $100,000 would…

77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Science.gov (United States)

2012-11-01

... BOUCHARD RAYMOND JOSEPH BOULLE II JEAN-RAYMOND BROMLEY MARGARET ANNE BROWNE CARLA EVELYN BRUCE JAMES TODD... CAMINOS MICHELE CLARE CAMPBELL JESSICA ANNE CHANG WAYNE WEN TIEN CHAN-PALAY VICTORIA LYE-HUA CHEN HOPE MI... RICHARD JOSEPH ARTHUR FUKUDA MEGUMI GAEHWILER YANNIK PETER GEIGER DANIEL CHRISTIAN GEIGER MICHAEL MATTHIAS...

Research Investigation of Information Access Methods

Science.gov (United States)

Heinrichs, John H.; Sharkey, Thomas W.; Lim, Jeen-Su

2006-01-01

This study investigates the satisfaction of library users at Wayne State University who utilize alternative information access methods. The LibQUAL+[TM] desired and perceived that satisfaction ratings are used to determine the user's "superiority gap." By focusing limited library resources to address "superiority gap" issues identified by each…

Military Professionalism and the Early American Officer Corps, 1789-1796

Science.gov (United States)

2013-06-13

and trust in Wayne rose to new heights, illustrating both the power of success and the current Army doctrinal understanding that “ cementing trust...to fight the British, Hamtramck’s Catholic faith, fluency in French, and overall care for the civilian populace endeared him to the largely French

Keeping Stem Cells in Check: A Hippo Balancing Act

NARCIS (Netherlands)

Vermeulen, Louis

2013-01-01

Knowing when to stop proliferation is crucial for any regenerative process. In a recent issue of Nature, Barry et al. (2012) report that the Hippo pathway component YAP negatively regulates Wnt signaling, thereby preventing stem cell overpopulation after a regenerative response in the intestine

TB in Captive Elephants

Centers for Disease Control (CDC) Podcasts

2017-04-27

Dr. Barry Kreiswirth, founding director of the Public Health Research Institute, TB Center, at Rutgers University, discusses TB in three captive elephants.  Created: 4/27/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 4/27/2017.

Journal of Endocrinology, Metabolism and Diabetes of South Africa ...

African Journals Online (AJOL)

Adrenocortical function in hospitalised patients with active pulmonary tuberculosis receiving a rifampicin-based regimen - a pilot study · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. WD Francois Venter, Vanessa R Panz, Charles Feldman, Barry I Joffe, 16-21.

The relationship between nutritionally-related blood metabolites and ...

African Journals Online (AJOL)

user

goat is reputable mainly for its adaptability and resistance to diseases and parasites (Barry & Godke, 2001). It is, however ... the various nutritional and metabolic disorders (Daramola et al., 2005) in goats. The discovered .... Biochemical and haematological measurements in beef cattle in Mendoza plain rangelands ...

Environmental Characterization of Mine Countermeasure Test Ranges: Hydrography and Water Column Optics

Science.gov (United States)

2015-09-30

RESULTS In general, water transparency improved over time during the second and third weeks after the passage of hurricane Barry. The vertical...relationship between visible and near-infrared reflected light from corals, macroalgae and micralgae. Submitted to CoBOP Special Issue of Limnology and

La varicocèle de l'adulte: aspects anatomo-cliniques et resultats ...

African Journals Online (AJOL)

La varicocèle de l'adulte: aspects anatomo-cliniques et resultats therapeutiques au service d'urologie-andrologie du CHU de Conakry, Guinee. AB Diallo, I Bah, M Barry, TMO Diallo, MD Bah, D Kanté, D Cissé, OR Bah, MB Diallo ...

African Journal of Urology - Vol 12, No 3 (2006)

African Journals Online (AJOL)

La fistule penienne apres circoncision: A propos de 22 cas · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. AB Diallo, I Bah, M Barry, OR Bah, S Balde, KB Sow, MB Diallo, I Balde, 152-155 ...

CD review: Giving voice to hope: music of Liberian refugees | Thorn ...

African Journals Online (AJOL)

Title: Giving voice to hope: music of Liberian refugees (2009). One compact disk and booklet. Production supervision by Barry Tonge, Michael Frishkopf, Nancy Hanneman, Ellis Pourbaix and Jennifer Woronuk. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

Life Beyond Walls. Proceedings of the National Conference on Outdoor Recreation (Ft. Collins, Colorado, November 10-13, 1988).

Science.gov (United States)

Gilbert, Jim, Ed.; Bruner, Eric, Ed.

This proceedings contains 16 papers on recreation and adventure programming, outdoor education, and outdoor leadership training. The papers are: (1) "Beyond Recreation: Our Classroom Is Wild America" (Barry Auskern); (2) "Outward Bound Leadership Model: An Exploratory Study of Leadership Variables" (Natalie L. Bartley); (3)…

Ugh! Ulcers

Science.gov (United States)

... believed that ulcers were caused by stress and spicy foods. Then, in 1982, two doctors (Barry Marshall and ... not develop ulcers. Doctors still aren't sure why, but they think that part ... of pain relievers , like aspirin or ibuprofen, can cause ulcers in some ...

Initial results of a new generation dual source CT system using only an in-plane comb filter for ultra-high resolution temporal bone imaging.

Science.gov (United States)

Meyer, Mathias; Haubenreisser, Holger; Raupach, Rainer; Schmidt, Bernhard; Lietzmann, Florian; Leidecker, Christianne; Allmendinger, Thomas; Flohr, Thomas; Schad, Lothar R; Schoenberg, Stefan O; Henzler, Thomas

2015-01-01

To prospectively evaluate radiation dose and image quality of a third generation dual-source CT (DSCT) without z-axis filter behind the patient for temporal bone CT. Forty-five patients were either examined on a first, second, or third generation DSCT in an ultra-high-resolution (UHR) temporal bone-imaging mode. On the third generation DSCT system, the tighter focal spot of 0.2 mm(2) removes the necessity for an additional z-axis-filter, leading to an improved z-axis radiation dose efficiency. Images of 0.4 mm were reconstructed using standard filtered-back-projection or iterative reconstruction (IR) technique for previous generations of DSCT and a novel IR algorithm for the third generation DSCT. Radiation dose and image quality were compared between the three DSCT systems. The statistically significantly highest subjective and objective image quality was evaluated for the third generation DSCT when compared to the first or second generation DSCT systems (all p generation examination as compared to the first and second generation DSCT. Temporal bone imaging without z-axis-UHR-filter and a novel third generation IR algorithm allows for significantly higher image quality while lowering effective dose when compared to the first two generations of DSCTs. • Omitting the z-axis-filter allows a reduction in radiation dose of 50% • A smaller focal spot of 0.2 mm (2) significantly improves spatial resolution • Ultra-high-resolution temporal-bone-CT helps to gain diagnostic information of the middle/inner ear.

Restoring Wisconsin Art Therapy Association in Art Therapy History: Implications for Professional Definition and Inclusivity

Science.gov (United States)

Potash, Jordan; Burnie, Michele; Pearson, Rosemary; Ramirez, Wayne

2016-01-01

The Wisconsin Art Therapy Association (WATA), formally established in 1969, was the first incorporated organization of art therapists in the United States. Under the leadership of Wayne Ramirez, WATA lobbied the national association for an inclusive definition of art therapy that aimed to foster respect for psychiatric, educational, and community…

An Analysis of the Attraction and Holding Power of Motor Skill Stations Used in a Mastery Motivational Physical Education Climate for Preschool Children

Science.gov (United States)

Hastie, Peter A.; Johnson, Jerraco L.; Rudisill, Mary E.

2018-01-01

Background: The template for the current study was the project conducted by Rosenthal [1973. "An Ecological Study of Free Play in the Nursery School." Doctoral diss., Wayne State University] where she investigated the attraction and holding power of various learning centres during free play in a naturalistic preschool setting.…

Teaching Commercial Law in the Third Year: A Short Report on a Business Organizations and Commercial Law Clinic.

Science.gov (United States)

Dolan, John F.; McNair, Russell A., Jr.

1995-01-01

The development and implementation of a clinic to offer advanced study in business organizations and commercial law transactions for third-year law students at Wayne State University (Michigan) are described. The course builds vertically on prior study and puts students in contact with practicing lawyers in an academic setting. Considerations…

Commentary: Addressing the Gap Between Science and Practice in Children's Mental Health

Science.gov (United States)

Walker, Hill M.

2003-01-01

The article by Fantuzzo, McWayne, and Bulotsky (2003), presenting their conceptualization of a paradigm for conducting applied research in children's mental health, is an intriguing fusion of key principles and recommendations. Their model comes close to meeting the profile of a new research paradigm in children's mental health. The author…

Saine diversification des repas servis dans les écoles grâce aux ...

International Development Research Centre (IDRC) Digital Library (Canada)

Saine diversification des repas servis dans les écoles grâce aux innovations en agriculture. 03 janvier 2018. Wendy-Ann Isaac, Gaius Eudoxie, Patrick Cortbaoui, Wayne Ganpat et Sylvia Borucki. Des élèves qui mangent un repas à l'école. Photo : Arne Hoel / Banque mondiale ...

76 FR 67175 - Riverbank Hydro No. 2 LLC, Lock Hydro Friends Fund XXXVI, Arkansas Electric Cooperative Corp...

Science.gov (United States)

2011-10-31

...; 14149-000] Riverbank Hydro No. 2 LLC, Lock Hydro Friends Fund XXXVI, Arkansas Electric Cooperative Corp... Lock Hydro Friends Fund XXXVI (Lock Hydro) and on April 11, 2011, Arkansas Electric Cooperative Corp... & Dam No. 3, as directed by the Corps. Applicant Contact: Mr. Wayne F. Krouse, Hydro Green Energy, 5090...

Librarians as Organic Intellectuals: A Gramscian Approach to Blind Spots and Tunnel Vision.

Science.gov (United States)

Raber, Douglas

2003-01-01

Discusses Wayne Wiegand's article that criticizes library and information science and its role in relations of power and knowledge, and suggests that the work of Antonio Gramsci can help understand how libraries and users are conditioned by history and politics. Considers Gramsci's Marxism; historical subjects and hegemony; and political strategy.…

An Analysis of How Building a Collaborative Community of Professional Social Studies Teachers through Targeted Ambient Professional Development Impacts Social Studies Classroom Practices

Science.gov (United States)

Thomas-Brown, Karen; Shaffer, LaShorage; Werner, Sharon

2016-01-01

This study examined the impact of a yearlong ambient professional development (PD) program-The Wayne Schools Global Geography Project (WSGG-project)-that focused on improving teacher quality through PD and classroom observations for in-service social studies teachers. The project targeted middle and high school social studies teachers and used…

Fulltext PDF

Indian Academy of Sciences (India)

593 The Spirit of Adventure and the Art of Creation. Camphor to Vitamin B12. Setty Mallikarjuna Babu and Subramania Ranganathan. 624 Eschenmoser Approach to Vitamin B12 by A/D. Strategy. An Unexpected Journey. G Wayne Craig. 641 The Total Synthesis of Strychnine. Edited by Setty Mallikarjuna Babu and.

75 FR 14488 - Public Notice for Waiver of Aeronautical Land-Use Assurance; James N. Cox Dayton International...

Science.gov (United States)

2010-03-25

...: Irene R. Porter, Program Manager, Detroit Airports District Office, 11677 South Wayne Road, Suite 107, Romulus, MI 48174 FOR FURTHER INFORMATION CONTACT: Irene R. Porter, Program Manager, Federal Aviation... Dayton as recorded in Deed Book 1616, Page 505 and part of a 12.07 acre tract (Parcel 21) conveyed to The...

Urbanism and Voter Turnout: A Note on Some Unexpected Findings

Science.gov (United States)

Monroe, Alan D.

1977-01-01

Analysis of voter turnout reveals rural areas to have much higher turnout than urban. Furthermore, these rural areas have lower levels of education, income, and industrialization. Several theoretical arguments are examined. Available from: the Wayne State University Press, 5980 Cass Avenue, Detroit, Michigan 48202, $4.00 single copy. (Author/MLF)

A Comparison of the DISASTER (Trademark) Scheduling Software with a Simultaneous Scheduling Algorithm for Minimizing Maximum Tardiness in Job Shops

Science.gov (United States)

1993-09-01

goal ( Heizer , Render , and Stair, 1993:94). Integer Prgronmming. Integer programming is a general purpose approach used to optimally solve job shop...Scheduling," Operations Research Journal. 29, No 4: 646-667 (July-August 1981). Heizer , Jay, Barry Render and Ralph M. Stair, Jr. Production and Operations

A Comparative Study between U.S. and Brazilian Acquisition Regulations and Practices

Science.gov (United States)

2011-03-01

to describe continuous improvements efforts ( Render and Heizer , 2008). Caddick and Dale (1998) on their paper ‘The impact of quality management on...2002). Outsourcing in Edinburgh and the Lothians. European Journal of Purchasing and Supply Chain Management 8 (2) 83-95. Render , Barry; Heizer , Jay

Kulmudeni püssirohutolmus / Lauri Saaber

Index Scriptorium Estoniae

Saaber, Lauri

1999-01-01

Komöödiast "Metsik metsik Lääs" ("Wild Wild West") : režissöör Barry Sonnenfeld : Ameerika Ühendriigid 1999. Kriminaalkomöödia "Hunnik pappi ja suitsev kaheraudne" ("Lock, Stock & Two Smoking") : režissöör Guy Ritchie : Suurbritannia 1999

77 FR 17034 - Procurement List; Addition

Science.gov (United States)

2012-03-23

...: Base Supply Center, National Maritime Intelligence Center/Office of Naval Intelligence, 4251 Suitland... Activity: Dept. of the Navy, Office Of Naval Intelligence, Washington, DC. Barry S. Lineback, Director, Business Operations. [FR Doc. 2012-7006 Filed 3-22-12; 8:45 am] BILLING CODE 6353-01-P ...

Helicobacer pylori detection using local (in-house) rapid Urease ...

African Journals Online (AJOL)

Background: Since the discovery of Helicobacter pylori (H. pylori) by Robin Warren and Barry Marshall in 1982 and its subsequent association with diseases like antral (type B) gastritis, peptic ulcer disease (PUD), gastric cancer and gastric Mucosal Associated Lymphoid Tissue (MALT) lymphoma, various invasive as well ...

76 FR 27175 - Quarterly Publication of Individuals Who Have Chosen To Expatriate, as Required by Section 6039G

Science.gov (United States)

2011-05-10

... name First name Middle name/initials ABA MAUREEN ABASI HAJIYA ABRAHAMS STEPHANIE JANE ABRIC ISABELLE H... BENNETT EDWARDS STEPHEN EGLI CAROLINE ANNE ELKOREK MAYA EMERSON BARBARA MARIE EMERY JEAN CHRISTOPHE... NOBUKO KEATS BARRY R KEMELMAN ARNON KERR MAYA CHANTAI KEUNG PAUL HINSUM KEUNG PAUL H KEWAIRAMANI SONALI...

Kirg maalida

Index Scriptorium Estoniae

2006-01-01

Eesti Kunstnike Koondise Torontos liikmest Selma Pihelist, kelle loomeenergia on jätkuv, nüüd on ta jõudnud esimese personaalnäituseni " A Passion to Paint", mis avatakse 12. novembril Barrie Art Club´is ja jääb avatuks 28. detsembrini

76 FR 45542 - Procurement List; Proposed Addition

Science.gov (United States)

2011-07-29

... Feeding and Cleaning. NPA: NewView Oklahoma, Inc., Oklahoma City, OK. Contracting Activity: Defense Logistics Agency Troop Support, Philadelphia, PA. Coverage: C-List for 100% of the requirement of the Department of Defense, as aggregated by the Defense Logistics Agency Troop Support, Philadelphia, PA. Barry S...

77 FR 71400 - Procurement List, Additions

Science.gov (United States)

2012-11-30

.... Contracting Activity: DEFENSE LOGISTICS AGENCY TROOP SUPPORT, PHILADELPHIA, PA. Coverage: C-List for 100% of the requirement of the Department of Defense, as aggregated by the Defense Logistics Agency Troop... ARMY, W071 ENDIST KANSAS CITY, KANSAS CITY, MO. Barry S. Lineback, Director, Business Operations. [FR...

South African Medical Journal - Vol 91, No 11 (2001)

African Journals Online (AJOL)

... in uncomplicated Plasmodium falciparum malaria 3 years after introduction in Mpumalanga · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Aaron Mabuza, John M. Govere, David N. Durrheim, Barry L.F. Bredenkamp, Brian L. Sharp, Karen Barnes, 975-978 ...

A Prospective Investigation of Biomechanical Risk Factors for Patellofemoral Pain Syndrome. The Joint Undertaking to Monitor and Prevent ACL Injury (JUMP-ACL) Cohort

Science.gov (United States)

2009-09-24

tors: Brent Arnold, Shrikant Bangdiwala, Barry Boden, Kenneth Cameron, Thomas DeBerardino, David Keblish, Marjorie King, Robert Sullivan, John Tokish...Clin Biomech. 2007;22:681-688. 24. Shrier I, Ehrmann-Feldman D, Rossignol M, Abenhaim L. Risk fac- tors for development of lower limb pain in

Deterrence at the Operational Level of War

Science.gov (United States)

2011-01-01

edited, with Barry Blechman, Making Defense Reform Work (Brassey’s, 1990) and has also authored numerous books and articles . Deterrence at the...computational power. In contrast, many models of rational inference view the mind as if it were a supernatural being possessing demonic powers of reason

The Simulation of a Major Automated Information System (AIS) on a Microcomputer

Science.gov (United States)

1984-03-01

The AIS would be selected from a public zec cor application. Rationale for this choice are: a. Many public sector organizations have a far richer...19. Boehm, Barry W. and others, Characteristics of Software Quality, North-Holland, 1978. 20. Freeman, Peter and Wasserman, Anthony I., Tutorial on

LIGO: The strong belief

CERN Multimedia

Antonella Del Rosso

2016-01-01

Twenty years of designing, building and testing a number of innovative technologies, with the strong belief that the endeavour would lead to a historic breakthrough. The Bulletin publishes an abstract of the Courier’s interview with Barry Barish, one of the founding fathers of LIGO.   The plots show the signals of gravitational waves detected by the twin LIGO observatories at Livingston, Louisiana, and Hanford, Washington. (Image: Caltech/MIT/LIGO Lab) On 11 February, the Laser Interferometer Gravitational-Wave Observatory (LIGO) and Virgo collaborations published a historic paper in which they showed a gravitational signal emitted by the merger of two black holes. These results come after 20 years of hard work by a large collaboration of scientists operating the two LIGO observatories in the US. Barry Barish, Linde Professor of Physics, Emeritus at the California Institute of Technology and former Director of the Global Design Effort for the Internat...

Liberalismo igualitário e multiculturalismo Equalitarian liberalism and multiculturalism

Directory of Open Access Journals (Sweden)

Álvaro de Vita

2002-01-01

Full Text Available Sendo o multiculturalismo um dado de fato das sociedades contemporâneas, examinam-se os méritos de duas respostas a ele: a do multiculturalismo (na sua acepção normativa e a do liberalismo igualitário (aqui representado por Brian Barry na sua obra mais recente. Defende-se a segunda concepção e critica-se o multiculturalismo normativo, entre outras razões por desviar a atenção dos fatores mais importantes de desvantagem social dos grupos discriminados.Since multiculturalism is a matter of fact in contemporary societies the respective merits of two answers to it are examined: the multiculturalist (in the normative meaning of the term and the equalitarian liberal (represented here by Brian Barry in his most recent work. The second conception is defended and normative multiculturalism is criticized, among other reasons for turning away the attention from the most important factors of social handicap of the discriminated groups.

Disrupted Social Work Field Placement: Factors That Contribute to Premature Termination of BSW Students' Field Placement

Science.gov (United States)

Tyler, Janet

2012-01-01

According to R. Wayne ("Legal Guidelines for Dismissing Students Because of Poor Performance in the Field," 2004), there is a widely accepted assumption in social work education that field placement provides the best opportunity to evaluate students' goodness-of-fit with the profession and is therefore used to weed out unsuitable…

76 FR 38162 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

Science.gov (United States)

2011-06-29

... concurred on this decision to make an exception to Section 1605 of ARRA. This action permits the purchase of... United States of a satisfactory quality] to Wayne County for the purchase of Link-Pipe PVC products in... specifications and requirements. The Regional Administrator is making this determination based on the review and...

Saladusloor varjab CIA lennuki lende Eestisse / Kadri Paas

Index Scriptorium Estoniae

Paas, Kadri, 1982-

2005-01-01

USA uuriv ajakirjanik Wayne Madsen väidab, et kui 2003. aasta 12. jaanuaril Pärnus maandunud CIA lennuki pardal ei olnud vangid, vedas see ülisalajast ohtlikku laadungit. Eesti valitsus ei kavatse antud lennu kohta Ameerika Ühendriikidelt järelpärimist teha. Vt. samas: Need firmad sõidutavad vange

Semiconductor Deposition and Etching Interactions of Laser-Generated Translationally Hot Atoms and Radicals

Science.gov (United States)

1991-05-01

fluorescence," J. Chem. Phys. 86, 6731 (1987). J. E. Smedley , H. K. Haugen and S. R. Leone, "Collision-induced dissociation of laser- excited Br 2 [B3Fl(Ou... Robert J. Levis, postdoc, presently Assistant Professor of Chemistry, Wayne State University. Lisa M. Cousins, graduate student, Ph.D. 1989, presently

Trapped in Our Own Discursive Formations: Toward an Archaeology of Library and Information Science.

Science.gov (United States)

Radford, Gary P.

2003-01-01

Introduces Michel Foucault's "Archaeology of Knowledge" as a way of addressing Wayne Wiegand's charges of problems in the discipline of library and information science. Highlights include a discussion of discursive formations, or the ways in which a collection of texts are organized with respect to each other; and history as a discursive…

77 FR 76415 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Redesignation of...

Science.gov (United States)

2012-12-28

... Area is composed of Cabell and Wayne Counties and the Graham Tax District in Mason County in West... reviewing SIP submissions, EPA's role is to approve state choices, provided that they meet the criteria of... notes that it will not impose substantial direct costs on tribal governments or preempt tribal law. B...

A "Gay" Identity Emerges on Campus Amidst a Sea of Prejudice

Science.gov (United States)

Cullinan, Robert G.

1973-01-01

Subjects were ten male volunteers from Wayne State University's Gay Liberation Front who were interviewed and given the Tennessee Self Concept Scale. The results reinforce the view that the homosexual's self concept in general falls within expectations according to national norms. These ten men, at least, tended to view their homosexuality as a…

Understanding Treatment of Mild Traumatic Brain Injury in the Military Health System

Science.gov (United States)

2016-04-18

between sex and persistent care. This differs from the findings of Guinto and Guinto-Nishimura (2014), Bazarian and Atabaki (2001), and Farace and Alves...RAND Corporation, MG-720-CCF, 2008, pp. 169–234. As of January 13, 2015: http://www.rand.org/pubs/monographs/MG720.html Farace , Elana, and Wayne

77 FR 12361 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2012-02-29

... Martin C. Baschab Donald Hooper Gregory Chiropolos Ronnie G. Lynn Malinda N. Parks Mark Smith Stephen C... experience driving a CMV with the vision deficiency: Joshua H. Boatright Domingo V. Perez James F. Blush Dean.... Pinson Wayne L. Green Stephen R. Marshall James A. Fassbender The following 6 applicants were denied for...

78 FR 45956 - Notice of Inventory Completion: Hamilton County Department of Parks and Recreation, Hamilton...

Science.gov (United States)

2013-07-30

... osteological analysis of the human remains as a whole has not been completed. The human remains underwent archaeological processing and analysis under the direction of Indiana University Purdue University at Ft. Wayne... tooth; 1 lot of mussel shell fragments; 1 lot of non-formal uniface; 2 lots of ochre; 1 pestle fragment...

Mentoring as a Way to Change a Culture of Academic Bullying and Mobbing in the Humanities

Science.gov (United States)

Metzger, Angela M.; Petit, Angela; Sieber, Sharon

2015-01-01

In 2009, the "Chronicle of Higher Education" defined "academic mobbing" as "a form of bullying in which members of a department gang up to isolate or humiliate a colleague". In their call for a special issue on mobbing for "Workplace: A Journal for Academic Labor", editors Stephen Petrina and E. Wayne Ross…

76 FR 77728 - Process for a Designated Contract Market or Swap Execution Facility To Make a Swap Available To...

Science.gov (United States)

2011-12-14

... Mar. 8, 2011 at 2; Letter from Dexter Senft, Morgan Stanley, dated Mar. 2, 2011 at 4; Letter from... from Dexter Senft, Morgan Stanley, dated Mar. 2, 2011 at 4; Letter from Timothy Cameron, Securities... Wayne Pestone, FX Alliance Inc., dated Nov. 4, 2011 at 9-10. \\57\\ Letter from Dexter Senft, Morgan...

Thoughts on "Reconsidering the Washington-Du Bois Debate: Two Black Colleges in 1910-1911" and Thoughts on "Liberalism at the Crossroads: Jimmy Carter, Joseph Califano, and Public College Desegregation."

Science.gov (United States)

Edwards, Anthony

These two papers offer critiques of two essays that appeared in "Essays in Twentieth-Century Southern Education: Exceptionalism and its Limits," edited by Wayne J. Urban. The first paper examines Linda Buchanan and Philo Hutcheson's interpretation of the debate which underscored the well-known conflict between Booker T. Washington-W.E.B.…

Librarians and Party Girls: Cultural Studies and the Meaning of the Librarian.

Science.gov (United States)

Radford, Marie L.; Radford, Gary P.

2003-01-01

Responds to Wayne Wiegand's article that criticizes library and information science by suggesting a cultural studies approach to the field. Applies the work of Stuart Hall to a media stereotype of the female librarian based on the film "Party Girl" to allow new interpretations of media images of the profession. (Author/LRW)

Could cut-price cardiovascular procedures in India help Europe's hard-pressed health-care systems?

Science.gov (United States)

2011-05-01

Until recently, travelling to India for a cardiovascular procedure was unheard of, but huge improvements in the quality of medical care available in the subcontinent, and its relative cheapness, have fostered the growth of 'medical tourism' and could impact on health care in Europe, reports Barry Shurlock, PhD.

Security: Individuals and Leviathans

Science.gov (United States)

2013-05-20

involved named their action Operation Unified Protector. A principal author of the Right to Protect, adopted at the 2005 UN World Summit, Gareth Evans...Perspectives on and beyond Asia, ed Amitav Acharya and Barry Buzan (New York: Routledge, Taylor and Francis Group, 2010), 41-43. 127 Andrew Browne

Model of learning for practitioners in dementia care with music therapy as the joint focal point

DEFF Research Database (Denmark)

Ottesen, Aase Marie

Method and the theoretical frame of reference for the project; for example Daniel Stern's theory of senses of self, forms of vitality, the present moment, Barry Reisbergs research on retrogenesis and the recent research on mirror neurons. Methodically the project is organized as a case study of a music...

Onderzoek naar viswering en visgeleiding bij 7 gemalen in Nederland (met bijdragen van M.C.M. Bruijs en H.V. Winter)

NARCIS (Netherlands)

Kroes, M.J.; Boer, de M.B.E.; Bruijs, M.C.M.; Winter, H.V.

2013-01-01

Gemalen vormen een barrière voor vismigratie van met name schieraal. De vraag is in welke mate schade en sterfte optreedt onder vis die pogingen onderneemt om het opvoerwerk te passeren of juist onvrijwillig door poimpen wordt ingezogen. In opdracht van STOWA is een grootschalig onderzoek uitgevoerd

African Journal of Paediatric Surgery - Vol 3, No 1 (2006)

African Journals Online (AJOL)

Acute Intussusception in childhood: Aspects of epidemiologic, Clinical Features and Management at Children's Hospital, Donka, Guinea Conakry · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. M Keita, O T Barry, N Doumbouya, A F Diallo, B M Toure, I Balde, 1-3 ...

Joint Services Electronics Program. Appendix

Science.gov (United States)

1992-11-01

R.E. Kleinman, Electromagnetic and (Raleigh- Ritz ), Galerkins method, and the method of Acoustic Scattering by Simple Shapes, J.J. Bowman, least...71 C. Namislo, "Analysis of mobile radio slotted ALOHA networks," IEEE the M. Barry Carlton Award for best paper from the IEEE Aerospace and Tram

Russia, China, and the United States in Central Asia: Prospects for Great Power Competition and Cooperation in the Shadow of the Georgian Crisis

Science.gov (United States)

2009-02-01

energy, public health, and food safety) shape Chinese foreign relations with neighboring states. Professor Wishnick also writes about great power...Dismisses Georgia’s Leader as ‘Political Corpse’,” The New York Times, September 3, 2008, p. A10; Ellen Barry, “Russians with Pumpkins Protest Many U.S

C9H14N

Indian Academy of Sciences (India)

J. Chem. Sci. Vol. 128, No. 7, July 2016, pp. 1037–1045. c Indian Academy of ..... Teraski O, Barry J C and Thomas J M 1987 Nature ... Betteridge P W, Carruthers J R, Cooper R I, Prout K and ... Clegg W and Watson D G 2007 Acta Cryst.

Our Way of Life May Be Killing Us.

Science.gov (United States)

USA Today, 1979

1979-01-01

Temple University psychologist Barry Harris notes that today the major causes of death and chronic illness in the United States are stress-related. He asserts that traditional medical care, focused on disease, is inadequate and should be replaced by a strategy emphasizing healthy living and stress management. (Author/SJL)

Is dit de grenswaarde?

NARCIS (Netherlands)

Pieters, M.; de Jong, G.; van der Hoorn, T.

2010-01-01

Het overschrijden van een landsgrens vormde in het verleden voor het personenverkeer een behoorlijke barrière: naast de tijd die het kostte bij de paspoortcontrole, betekende een ander land ook een andere historie, een andere cultuur, een andere taal en een andere valuta. Met de Europese eenwording

Solar Energy Now.

Science.gov (United States)

Rose, Harvey, Ed.

Twenty articles addressing different aspects of solar energy are compiled in this book. They represent the views of different governmental and non-governmental organizations, members of congress, and other individuals including, for example, Barry Commoner and Amory Lovins. Topics discussed include the need for federal support, passive solar…

Level of Dietary Fat Does Not Affect Fuel Oxidation or Endurance Exercise Performance of Soldiers

Science.gov (United States)

1991-03-15

prevent or slow depletion of the body’s limited carbohydrate (glycogen) reserves, and thereby maintain or restore the original ratio of carbohydrate-to-fat...micron; Microfiltration Systems, Dublin, CA). The final filtrate was used for the enzyme assay. All enzyme assays were run by Dr. Barry Goldin, Tufts

An Organizational Culture Perspective of Strategic Leadership and Organizational Change: Shaping the Future of the Army

Science.gov (United States)

1991-04-02

1989): 245-273; David M. Fetterman , Ethnography: Step by Step (Newbury Park, CA: Sage Publications Inc., 1989), 45-47; James P. Spradley, Participant...Denton, D. Keith, and Barry L. Wisdom. "Shared Vision." Business Horizons 32 (July-August 1989): 67-69. Fetterman , David M. Ethnography: Step by Step

A Reflection on Continuing Professional Education Research

Science.gov (United States)

Brennan, Barrie

2017-01-01

Barrie Brennan's thesis entitled "Continuing Professional Education in Australia. A Tale of Missed Opportunities" offers a history of Continuing Professional Development (CPD) in the Australian context. This paper arose from Brennan's research for his thesis and is focused on issues that arose from the introduction of Australia's…

KARAKTERISTIK KLINIS PENDERITA HIPERTIROID DI DAERAH ENDEMIK DAN NON ENDEMIK GAKI

Directory of Open Access Journals (Sweden)

Ina Kusrini

2012-10-01

Full Text Available Background: Iodine is the essential component for synthesis of tyroid. In the area of dificiency iodium the iodine intake was also obtained from high doses of iodine capsules and iodized salt. While in the area of non-iodine deficiency, iodine source may be more complex, considering a more varied diet and a lot of drugs containing iodine. The Wayne index used to estimate the suspect of hyperthyroidism but to get right diagnosis for hyperthyroidism are use laboratory examination. Positiv hyperthyroidsm if TSH in serum < 0,3 µlU/ml and FT4 > 2 nano gram/dl. Obyektives: The purpose of this paper is to view clinical characteristic in the nonendemik areas and endemic iodine deficiency disorder. Method: The method used is analitic research design with a crosssectional study. Respondent of the research are woman that age 15-50 years old. The number of samples in this research is 36 woman from endemic areas and 36 samples from non endemic areas. Analysis of data using excel and SPSS programs. Result: Results can be seen that in general clinical characteristics in two areas namely endemic and non endemic areas are not statistically different with p = 0.803 (p> 0.05. But in these two regions are typical symptoms of hyperthyroidism suspect in non-endemic area when compared with endemic areas such as the prominent and showed statistical differences in the symptoms exopthalmus value of p = 0.00, rapid pulse value p = 0.01, appetite increased with p-value = 0.03. alue index of sensitivity and specificity to predict hyperthyroid wayne in endemic areas is 0.67 and Se 0.87. While the value of sensitivity and specificity indices wayne to suspect hyperthyroidism in non-endemic areas is 0.55 and 0.925Se. Keywords: hyperthyroidism, endemic, non endemic, clinical characteristics

Long-Term Effects of Adderall XR in ADHD

Directory of Open Access Journals (Sweden)

J Gordon Millichap

2005-06-01

Full Text Available The long-term tolerability and effectiveness of extended release mixed amphetamine salts (Adderall XR in children with attention deficit hyperactivity disorder (ADHD were evaluated in a 24-month, multicenter, open-label extension of 2 placebo-controlled studies at UCLA, Massachusetts General Hospital, UC-Irvine, Maitland, FL, and Shire Pharmaceutical, Wayne, PA.

n narratiewe benadering tot die pastoraat: kritiese opmerkings na ...

African Journals Online (AJOL)

deur Carl Rogers bekend gemaak is en wat verder in die pastoraat ontgin is deur pastorale teoloë soos Wayne Oates, Paul Johnson en Carrol Wise. (De Jongh van Arkel 1988:2). Hierdie assimilering het egter beteken dat die aanspraak van die Woord nou ondergeskik aan die behoeftes van die persoon in beraad geword ...

A Homegrown Design for Data Warehousing: A District Customizes Its Own Process for Generating Detailed Information about Students in Real Time

Science.gov (United States)

Thompson, Terry J.; Gould, Karen J.

2005-01-01

In recent years the Metropolitan School District of Wayne Township in Indianapolis has been awash in data. In attempts to improve levels of student achievement, the authors collected all manner of statistical details about students and schools and attempted to perform data analysis as part of the school improvement process. The authors were never…

Obama, where Art Thou? Hoping for Change in U.S. Education Policy

Science.gov (United States)

Au, Wayne

2009-01-01

In this essay, Wayne Au carefully considers the educational stance of Barack Obama by exploring the president's speeches and his personnel and policy choices. Au considers the election of Obama as a moment of possibility for change in American education, but also questions whether Obama's hopeful message about education will be fully realized,…

Effects of ice storm damage on hardwood survival and growth in Ohio

Science.gov (United States)

Richard M. Turcotte; Thomas R. Elliott; Mary Ann Fajvan; Yong-Lak Park; Daniel A. Snider; Patrick C. Tobin

2012-01-01

In 2003, an ice storm occurred across four Mid-Atlantic states. This study investigated the effects of the ice-storm damage on growth and mortality of five tree species (Acer rubrum, Acer saccharum, Quercus alba, Quercus prinus, and Quercus rubra) from three forest stands in the Wayne National Forest in Ohio. We remeasured the same...

Image processing with ImageJ

NARCIS (Netherlands)

Abramoff, M.D.; Magalhães, Paulo J.; Ram, Sunanda J.

2004-01-01

Wayne Rasband of NIH has created ImageJ, an open source Java-written program that is now at version 1.31 and is used for many imaging applications, including those that that span the gamut from skin analysis to neuroscience. ImageJ is in the public domain and runs on any operating system (OS).

Dewey Decimal Classification for U. S. Conn: An Advantage?

Science.gov (United States)

Marek, Kate

This paper examines the use of the Dewey Decimal Classification (DDC) system at the U. S. Conn Library at Wayne State College (WSC) in Nebraska. Several developments in the last 20 years which have eliminated the trend toward reclassification of academic library collections from DDC to the Library of Congress (LC) classification scheme are…

Definitions of Cyber Terrorism

NARCIS (Netherlands)

Luiijf, H.A.M.

2014-01-01

The phrase cyber terror appeared for the first time in the mid-eighties. According to several sources, Barry C. Collin, a senior person research fellow of the Institute for Security and Intelligence in California, defined cyber terror at that time as “the convergence of cybernetics and terrorism”—an

Maori on the Silver Screen: the evolution of indigenous feature filmmaking in Aotearoa/New Zealand

NARCIS (Netherlands)

Martens, E.

2012-01-01

This article examines the evolution of Maori filmmaking since the 1980s and explores this Indigenous cinema in the context of developments in the New Zealand film industry. With Barry Barclay’s idea of ‘Fourth Cinema’ in mind, it focuses on the predominantly state-funded production of Maori feature

Nursing Education Leaders' Perceived Leadership Practices

Science.gov (United States)

DeLong, Dianne

2010-01-01

The purpose of this study was to examine the leadership practices perceived by nursing education leaders as measured by the Leadership Practices Inventory (LPI). The framework used was a contemporary transformational leadership model described in "The Leadership Challenge" ("4th ed.") by Dr. James Kouzes and Dr. Barry Posner,…

Présentation des conseillers régionaux du CRDI sur le Dialogue ...

International Development Research Centre (IDRC) Digital Library (Canada)

test

les chercheurs communiquent mieux leurs résultats. > populations bénéficient des résultats de recherche. > les décideurs puisent des solutions dans le réservoir intarissable des chercheurs. > Comment lever certaines barrières qui inhibent le rapprochement entre chercheurs et décideurs ?

United States Civil Military Relations: Defense Reform

Science.gov (United States)

2016-03-01

1064–6. (1986). 211 Barry M. Goldwater and Jack Casserly, Goldwater (New York, NY: St. Martin’s Press, 1988), 453. 212 Katherine Boo , “How...Unfinished Business.” The American Interest 7, no. 4 (April 2012). http://www.the-american-interest.com/2012/02/02/unfinished-business/. Boo , Katherine

“As jou broer verkeerd opgetree het teen jou ...”: Enkele aspekte van ...

African Journals Online (AJOL)

p1243322

teen jou ...”: Enkele aspekte van kerklike dissipline uit die Kerkorde van die Nederduitsch Hervormde. Kerk van Afrika. B J (Barry) van Wyk. Hervormde Teologiese Kollege. Universiteit van Pretoria. Abstract. “If a brother sins against you ...”: Certain aspects of church discipline from the Church Ordinance of the. Netherdutch ...

Runaway Reaction: Solving for X.

Science.gov (United States)

Bartz, Solveig A.

2003-01-01

This article examines the runaway reaction as it was displayed by Barry, a 14-year-old eighth-grade boy with learning disabilities. It identifies some of the common characteristics of this response and proposes school intervention methods. Functional behavioral assessments and strength-based assessments are encouraged, along with using strategy…

A Collection of Reprints,

Science.gov (United States)

1986-01-01

144. Wiley Interscience, New York. Csanady, G. T., 1981, Circulation in the coastal ocean. In (Barry Saltzman , ed.) Advances in Geophysics. Academic...Deep-Sea Res., 13:607-620. Hurlburt, H. E. and J. Dana Thompson, 1973, Coastal upwelling on a beta-plane. J. Phys. Oceanogr., 3(l):16-32. Huthnance

Altered Middle Lamella Homogalacturonan and Disrupted Deposition of (1¿5)-a -_L-Arabinan in the Pericarp of Cnr, a Ripening Mutant of Tomato¹

DEFF Research Database (Denmark)

Orfila, C.; Seymour, G.B; Willats, William George Tycho

2001-01-01

Cnr (colorless non-ripening) is a pleiotropic tomato (Lycopersicon esculentum) fruit ripening mutant with altered tissue properties including weaker cell-to-cell contacts in the pericarp (A.J. Thompson, M. Tor, C.S. Barry, J. Vrebalov, C. Orfila, M.C. Jarvis, J.J. Giovannoni, D. Grierson, G...

Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

Directory of Open Access Journals (Sweden)

Lele Cui

2018-01-01

Full Text Available Purpose. To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT. Methods. Twenty participants (4 males and 16 females, 23.0 ± 3.7 years were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral PoLTF was determined. Results. The average conjunctival overlaps at insertion were 49% and 73% for galyfilcon A and balafilcon A lenses and increased significantly to 84% and 90% by 6 hours of lens wear (P<0.001. Lenses with rounded edges had more conjunctival overlap than the lenses with angled edges (P=0.014. There were significant decreases for PoLTF on the conjunctiva (P=0.014 and peripheral cornea (P=0.004 over the study period compared to insertion. The percentage of subjects with PoLTF on the conjunctiva (32.5% and peripheral cornea (36% were greater in subjects wearing balafilcon A lenses (P=0.017. Conclusions. Increased conjunctival overlap over the lens edges and reduced PoLTF underneath the peripheral region of soft contact lenses were shown during lens daily wear. The lens edge configuration may play a role in conjunctival response and peripheral PoLTF.

Pyrolusite Process® to remove acid mine drainage contaminants from Kimble Creek in Ohio: A pilot study

Science.gov (United States)

Shiv Hiremath; Kirsten Lehtoma; Mike Nicklow; Gary. Willison

2013-01-01

The Kimble Creek abandoned coal mine site, located on Wayne National Forest in southeastern Ohio, is among several abandoned coal mine sites that have been responsible for the acid mine drainage (AMD) polluting ground and surface water. Materials released by AMD include iron, aluminum, manganese, other hazardous substances, and acidity that are harmful to aquatic life...

Spotlight on RESA 2: Regional Implementation of the Learning School Initiative. Catalyst Schools Research Study Report

Science.gov (United States)

Hammer, Patricia Cahape

2016-01-01

West Virginia's Regional Education Service Agency 2 (RESA 2) serves six districts in the southwestern part of the state--Cabell, Lincoln, Logan, Mason, Mingo, Wayne--which together have 95 schools. RESA 2 was one of two RESAs to pilot implementation of the Learning School approach, beginning in the summer of 2014. RESA 2's first cohort included…

A Look at Child Care in a Northern Industrial State.

Science.gov (United States)

Miller, Michelle Russell, Ed.

This paper presents the results of three child care studies in the Oakland, Macomb, and Wayne Counties of Michigan. In the first study parents were surveyed to determine their child care needs versus the needs met by child care centers. Data was collected from seven child care centers: two franchise, three private, and two in-home. The conclusions…

Tallinna kohvikuturul võimutsevad lätlased / Andres Reimer

Index Scriptorium Estoniae

Reimer, Andres

2006-01-01

Läti kohvikukett Double Coffee kavatseb avada Tallinnas veel kuni 12 uut kohvikut, järgmine kohvik avatakse Lasnamäel. Urmas Sõõrumaale kuuluv Coffee Plus ning Rootsi päritolu Waynes Coffee Estonia püüavad muutuda lätlaste kohvikuketist võimalikult erinevaks. Double Coffee käive, kahjum. Lisa: Double Coffee äriidee

Predictions of fire behavior and resistance to control: for use with photo series for the ponderosa pine type, ponderosa pine and associated species type, and lodgepole pine type.

Science.gov (United States)

Franklin R. Ward; David V. Sandberg

1981-01-01

This publication presents tables on the behavior of fire and the resistance of fuels to control. The information is to be used with the publication, "Photo Series for Quantifying Forest Residues in the Ponderosa Pine Type, Ponderosa Pine and Associated Species Type, Lodgepole Pine Type" (Maxwell, Wayne G.; Ward, Franklin R. 1976. Gen. Tech. Rep. PNW-GTR-052....

Landscape variation in species diversity and succession as related to topography, soils and human disturbance

Science.gov (United States)

Jeffery N. Pearcy; David M. Hix; Stacy A. Drury

1995-01-01

Three hundred and thirty-two plots have been sampled on the Wayne National Forest of southeastern Ohio, for the purpose of developing an ecological classification system (ECS). The ECS will be based on the herbaceous and woody vegetation, soils and topography of mature (80-140 year-old), relatively-undisturbed forests. Species diversity changes little across this...

Nuclear waste management

International Nuclear Information System (INIS)

Wicks, G.G.; Ross, W.A.

1984-01-01

Papers from the Second International Symposium on Ceramics in Nuclear Waste Management, held during the American Ceramic Society's 85th Annual Meeting, comprise this eighth volume in the Advances in Ceramics series. The 81 papers included in this volume were compiled by George G. Wicks, of Savannah River Lab, and Wayne A. Ross, of Battelle, Pacific Northwest Labs

77 FR 12759 - Proposed Amendment of Class E Airspace; Tullahoma, TN

Science.gov (United States)

2012-03-02

... aviation safety is found in Title 49 of the United States Code. Subtitle I, section 106 describes the....) Winchester Municipal Airport (Lat. 35[deg]10'39'' N., long. 86[deg]03'58'' W.) Manchester Medical Center....) serving Manchester Medical Center. Issued in College Park, Georgia, on February 24, 2012. Barry A. Knight...

77 FR 28246 - Amendment of Class E Airspace; Tullahoma, TN

Science.gov (United States)

2012-05-14

... in Title 49 of the United States Code. Subtitle I, section 106 describes the authority of the FAA... Municipal Airport (Lat. 35[deg]10'39'' N., long. 86[deg]03'58'' W.) Manchester Medical Center, Point In...'' W.) serving Manchester Medical Center. Issued in College Park, Georgia, on April 30, 2012. Barry A...

Multiculturalism and Equal Treatment: Scope and Limits of the ...

African Journals Online (AJOL)

In this paper, I examine the scope and limits of Brian Barry's uniform treatment approach to cultural differences through a critical assessment of its two main arguments. The first maintains that under a regime of institutions serving legitimate public purposes, equal opportunity is an objective state of affairs, and religious or ...

Brief communication

Indian Academy of Sciences (India)

Prakash

by Dr L A Ballantyne, School of Agricultural and Wine. Sciences, Charles Sturt University, Australia. We also thank Professor Kalyanee Boruah for allowing us to use the facilities of the UHE Cosmic Ray Research Laboratory, and. Mr Simanta Hazarika and Mr Pradip Deka for their help in the laboratory. References. Barry J D ...

Pas de remède miracle

International Development Research Centre (IDRC) Digital Library (Canada)

publiques. Toutefois, l'éloignement, le manque d'éducation, les barrières linguistiques et la discrimination constante empêchent les populations autochtones d'exercer pleinement leurs droits. En 2007, une coalition dirigée par le Centro de Estudios para la Equidad y Gobernanza en los Sistemas de Salud a entrepris.

Learning Outcomes of 'Understanding Research' as understood by ...

African Journals Online (AJOL)

Simon Bhekumuzi

2015-11-23

Nov 23, 2015 ... Can Turnitin come to the rescue: From teachers' reflections? Simon Bheki Khoza ... In South Africa, however, there are very few schools that expose teachers to Turnitin in order to ... Turnitin program by John M. Barrie, when he was a graduate ... Questions. This article intended to explore and explain teach-.

Get to work on unemployment | Calitz | Law, Democracy ...

African Journals Online (AJOL)

Karen Calitz, Brenda Grant, Barry Shipman, Esther van Kerken. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

75 FR 69061 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2010-11-10

..., Linda C Burrows, Charles W Buttress, Larry D Buzzard, Christine M Cadieux, Gena E Callahan, Samuel N... Bekkedahl, Larry N Bell, Melody C Berkowitz, Barry E Bieniawski, Andrew J Bishop, Clarence T Bishop, Tracey..., Douglas E Kane, Michael C Kaplan, Stan M Kearney, James H Kelly, Henry C Kelly, Larry C Kenchington, Henry...

Neural Stem Cell Delivery of Therapeutic Antibodies to Treat Breast Cancer Brain Metastases

Science.gov (United States)

2010-10-01

Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS, Yoneda T, MacDonald IC, Chambers AF, Rutt BK, Foster PJ: In vivo MRI of cancer...Fransisco, CA). Caspase-3 was immunoprecipitated from cell lysates in the presence of protease inhibitors (Roche complete Mini tablet , EDTA-free and 2

78 FR 66012 - National Vaccine Injury Compensation Program; List of Petitions Received

Science.gov (United States)

2013-11-04

... Island; Court of Federal Claims No: 13-0632V 2. Kimberly Carter on behalf of Josselyn Kish; Henderson...; Whitesville, West Virginia; Court of Federal Claims No: 13-0641V 9. Barry S. Dezern, North Wilkesboro, North... Leonardo Munoz, Bowie, Maryland, Court of Federal Claims No: 13-0752V 88. Linda Vanslyke, Vienna, Virginia...

Accountability of the International Monetary Fund | CRDI - Centre de ...

International Development Research Centre (IDRC) Digital Library (Canada)

Accountability of the International Monetary Fund. Couverture du livre Accountability of the International Monetary Fund. Directeur(s):. Barry Carin et Angela Wood. Maison(s) d'édition: Ashgate, CRDI. 29 juin 2005. ISBN : 0754645231. 140 pages. e-ISBN : 1552501752. Téléchargez le PDF · Téléchargez le cyberlivre.

Solarstrom rund um die Uhr: Solarstrom mit Organic Rankine Cycle / erhöhte Solarausbeute / Fraunhofer UMSICHT

OpenAIRE

Schmidt, Mirjam; Hunstock, Björn; Bülten, Björn

2013-01-01

In einem Gastbeitrag beschäftigen sich die beiden Diplom-Ingenieure Björn Hunstock und Björn Bülten - beide wissenschaftliche Mitarbeiter des Fraunhofer-Instituts für Umwelt-, Sicherheits- und Energietechnik UMSICHT - mit solarthermisch angetriebenen Kraftwerken auf Basis der Organic Rankine Cycle (ORC) Technologie. Sie erläutern, in welchen Fällen und aus welchen Gründen diese als Alternative zu Photovoltaik-Anlagen in Betracht gezogen werden sollten. Sie wagen einen Vergleich der beiden Te...

Bon Pastor (Barcelona un territori en construcció

Directory of Open Access Journals (Sweden)

Xavier Salas Ramos

2016-04-01

Full Text Available L'article desenvolupa alguns dels aspectes de la tesi doctoral de l'autor (Sales, 2015. Es planteja una anàlisi de l'evolució del territori en el qual es troba el barri del Bon Pastor (Barcelona, posant l'accent en l'entorn construït. Per a això, la narrativa històrica es complementa amb documentació gràfica, part d'ella a partir dels diversos tallers de participació que l'autor ha desenvolupat i continua desenvolupant-se en aquest barri, en cooperació amb l'Associació de Veïns i l'Ajuntament de Barcelona (Districte de Sant Andreu amb l'objectiu de desenvolupar intervencions en l'espai públic de la zona en relació amb la preservació de la memòria cívica de Bon Pastor i en el context d'avançar en els processos de governaza urbana basada en la participació creativa dels veïns  Alhora s'organitzaven els primers processos participatius, vam començar a documentar la història de Bon Pastor. També a fer rutes pel barri per veure les seves característiques urbanes actuals i recopilar informació sobre els plans urbanístics vigents. Els següents paràgrafs són una síntesi del relat literari de la història de Bon Pastor i les seves principals característiques urbanes. Com va succeir amb Baró de Viver, és un relat que s'haurà d'anar completant a mesura que es desenvolupin els diferents processos participatius amb els relats de les vivències de la població, així com la diferent documentació que ens puguin aportar

Locus of Word Frequency Effects in Spelling to Dictation: Still at the Orthographic Level!

Science.gov (United States)

Bonin, Patrick; Laroche, Betty; Perret, Cyril

2016-01-01

The present study was aimed at testing the locus of word frequency effects in spelling to dictation: Are they located at the level of spoken word recognition (Chua & Rickard Liow, 2014) or at the level of the orthographic output lexicon (Delattre, Bonin, & Barry, 2006)? Words that varied on objective word frequency and on phonological…

Revue Africaine de Chirurgie et Spécialités - Vol 7, No 3 (2013)

African Journals Online (AJOL)

Complications du traitement traditionnel des fractures : aspects épidémiologiques et cliniques. EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. L Lamah, D Handy, ML Bah, D Onivogui, K Keita, S Sidime, IG Diallo, A Barry, MM Diallo, B Koivogui, ML Kaba, D Keita, AP Aboud, 31-35 ...

Debate: The Two Faces of African Feminism | Touré | CODESRIA ...

African Journals Online (AJOL)

Debate: The Two Faces of African Feminism. Abibatou Touré, Mamadou Cellou Barry, Pounthioun Diallo. Abstract. No Abstract Available CODESRIA Bulletin No 1 2003: 2-3. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

75 FR 4844 - Chesapeake and Ohio Canal National Historical Park Advisory Commission; Notice of Public Meeting

Science.gov (United States)

2010-01-29

.... Mr. Charles J. Weir. Mr. Barry A. Passett. Mr. James G. McCleaf, II. Mr. John A. Ziegler. Mrs. Mary E.... Gilford. Brother James Kirkpatrick. Dr. George E. Lewis, Jr. Mr. Charles D. McElrath. Ms. Patricia Schooley. Mr. Jack Reeder. Ms. Merrily Pierce. Topics that will be presented during the meeting include: 1...

75 FR 41520 - Chesapeake and Ohio Canal National Historical Park Advisory Commission; Notice of Public Meeting

Science.gov (United States)

2010-07-16

... Rabb Weidenfeld, Chairperson Mr. Charles J. Weir Mr. Barry A. Passett Mr. James G. McCleaf II Mr. John... Reynolds Dr. James H. Gilford Brother James Kirkpatrick Dr. George E. Lewis, Jr. Mr. Charles D. McElrath Ms. Patricia Schooley Mr. Jack Reeder Ms. Merrily Pierce Topics that will be presented during the meeting...

Introducing the Contextual Orientation to Bible: A Comparative Study

Science.gov (United States)

Levisohn, Jon A.

2008-01-01

Barry Holtz' (2003) presentation of a map of orientations for the teaching of Bible provides a certain kind of focus for research, enabling us to ask deeper and richer question about those orientations. This article investigates the teaching of one teacher, in two different settings--more specifically, how that teacher introduces Bible in those…

Infant Mental Health and the Treatment of Early Trauma

Science.gov (United States)

Lieberman, Alicia F.; Harris, William W.; Osofsky, Joy D.; Osofsky, Howard J.

2010-01-01

This article is excerpted and reprinted by permission of the publisher, Wiley-Blackwell, from the book "Nurturing Children and Families: Building on the Legacy of T. Berry Brazelton", edited by Barry M. Lester and Joshua D. Sparrow. In the first excerpt, Alicia F. Lieberman and William W. Harris explore the impact of violence and…

Unmanned Aerial Vehicle-Based Automobile License Plate Recognition System for Institutional Parking Lots

Directory of Open Access Journals (Sweden)

Julian Dasilva

2017-10-01

Full Text Available Unmanned aerial vehicles (UAVs, also known as drones have many applications and they are a current trend across many industries. They can be used for delivery, sports, surveillance, professional photography, cinematography, military combat, natural disaster assistance, security, and the list grows every day. Programming opens an avenue to automate many processes of daily life and with the drone as aerial programmable eyes, security and surveillance can become more efficient and cost effective. At Barry University, parking is becoming an issue as the number of people visiting the school greatly outnumbers the convenient parking locations. This has caused a multitude of hazards in parking lots due to people illegally parking, as well as unregistered vehicles parking in reserved areas. In this paper, we explain how automated drone surveillance is utilized to detect unauthorized parking at Barry University. The automated process is incorporated into Java application and completed in three steps: collecting visual data, processing data automatically, and sending automated responses and queues to the operator of the system.

Bicycles, Airplanes and Peter Pans: Flying Scenes in Steven Spielberg's Films

Directory of Open Access Journals (Sweden)

Emilio Audissino

2014-10-01

Full Text Available In Steven Spielberg's cinema the flight is a recurring theme. Flying scenes can be sorted into two classes: those involving a realistic flight – by aircraft – and those involving a magical flight – by supernatural powers. The realistic flight is influenced by the war stories of Spielberg's father – a radio man in U.S. Air-force during WWII – and it is featured in such films as Empire of the Sun (1987, Always (1989, and 1941 (1979. The magical flight is influenced by James M. Barries' character Peter Pan (Peter and Wendy, 1911, which is quoted directly in E.T. the Extraterrestrial (1982 and, above all, in Hook (1991, which is a sequel to Barrie's story. These two types of flying scenes are analysed as to their meanings, compared to the models that influenced them, and surveyed as to their evolution across Spielberg's films. A central case study is the episode The Mission from Amazing Stories (1985, in which the realistic and the magical flights overlap.

76 FR 78695 - Barry M. Schultz, M.D.; Decision and Order

Science.gov (United States)

2011-12-19

... process via the state hearing, and accordingly, under the facts of this case, has no constitutional right... not so narrowly tailored as to adhere to Florida Law and to protect his due process rights.'' [Id. at... process ``by allowing him to petition this Tribunal for either an abeyance of the Administration's...

Optimizing and Validating a Brief Assessment for Identifying Children of Service Members at Risk for Psychological Health Problems Following Parent Deployment

Science.gov (United States)

2016-07-01

Journal of Family Therapy, 21, 313-323. Behar, L.B. (1997). The Preschool Behavior Questionnaire. Journal of Abnormal Child Psychology , 5, 265-275... Psychological Health Problems Following Parent Deployment PRINCIPAL INVESTIGATOR: Julie Wargo Aikins, PhD CONTRACTING ORGANIZATION: Wayne State...Validating a Brief Assessment for Identifying Children of Service Members at Risk for Psychological Health Problems Following Parent Deployment 5b. GRANT

Payday for payers. Compensation of the top execs at investor-owned insurers outpaced that of the leaders at hospitals and specialty care.

Science.gov (United States)

Kutscher, Beth; Barr, Paul; Zigmond, Jessica

2012-08-13

Top executives at investor-owned hospital chains saw their compensation packages take a hit last year, amid the debt-ceiling crisis and concerns over how it might affect Medicare. Wayne Smith at Community Health Systems led the pack in that sector, with a $21 million payday, while Trevor Fetter, left, of Tenet, came in a distant second with $10.7 million.

40 CFR 81.315 - Indiana.

Science.gov (United States)

2010-07-01

... County X LaPorte County X Marion County X Porter County: An area bound on the north by Lake Michigan, on the west by the Lake-Porter County line, on the south by I-80 and 90 and on the east by the LaPorte-Porter County line ..... X The remainder of Porter County...... X Vigo County X Warrick County 1 X Wayne...

Tänavuses Nobeli meditsiinipreemias on ka saarlaste panus / Heidi-Ingrid Maaroos

Index Scriptorium Estoniae

Maaroos, Heidi-Ingrid, 1942-

2005-01-01

Tänavuse Nobeli meditsiinipreemia said Austraalia teadlased Barry J. Marshall ja Robin Warren Helicobacter pylori nimelise bakteri avastamise eest mao limaskesta põletiku ning mao- ja kaksteistsõrmiku haavandi tekitajana 1982. aastal. Saaremaaga on seekordne preemia seotud seetõttu, et 1979. aastal osalesid paljud saarlased mao limaskesta põletiku uuringus. Uuringute tulemusi kasutasid tulevased meditsiinipreemia laureaadid

African Journal of Urology - Vol 21, No 2 (2015)

African Journals Online (AJOL)

La varicocèle de l'adulte: aspects anatomo-cliniques et resultats therapeutiques au service d'urologie-andrologie du CHU de Conakry, Guinee · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. AB Diallo, I Bah, M Barry, TMO Diallo, MD Bah, D Kanté, D Cissé, OR Bah, ...

Revue Africaine de Chirurgie et Spécialités - Vol 11, No 1 (2017)

African Journals Online (AJOL)

Cas Clinique:Emasculation totale : à propos d'un cas · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. M.I.I. Barry, M. Keita, D. Kante, T.M.O. Diallo, M.D. Bah, A.B. Diallo, I. Bah, O.R. Bah, S. Guirassy, K.B. Sow, M.B. Diallo, 29-32 ...

African Journal of Urology - Vol 13, No 1 (2007)

African Journals Online (AJOL)

Traumatic Rupture of the Posterior Urethra. Analysis of 87 Cases at the Conakry University Hospital · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A B Diallo, M Barry, I Bah, A T Diallo, O R Bah, A Toure, S Balde, K B Sow, S Guirassay, M B Diallo, 62-71 ...

75 FR 65376 - Chesapeake and Ohio Canal National Historical Park Advisory Commission; Notice of Public Meeting

Science.gov (United States)

2010-10-22

.... Charles J. Weir Mr. Barry A. Passett Mr. James G. McCleaf II Mr. John A. Ziegler Mrs. Mary E. Woodward Mrs... Kirkpatrick Dr. George E. Lewis, Jr. Mr. Charles D. McElrath Ms. Patricia Schooley Mr. Jack Reeder Ms. Merrily Pierce Topics that will be presented during the meeting include: 1. Update on park operations. 2. Update...

Browse Title Index

African Journals Online (AJOL)

Items 1 - 50 of 1038 ... Vol 20 (1998), A GIS for the management of fisheries in West Africa: Preliminary application to the octopus stock in Senegal, Abstract PDF. E Foucher, M Thiam, M Barry. Vol 34, No 2 (2012), A hard-knock life: the foraging ecology of Cape cormorants amidst shifting prey resources and industrial fishing ...

Succesen blev fiaskoens moder

DEFF Research Database (Denmark)

Hansen, Per Henning

2015-01-01

Krise. Vi undgik det værste, men fordi vi var for dygtige til at lære af den store depression i 1930rne, fik vi aldrig ryddet ordentligt op. Så nu lurer en ny finanskrise ude i fremtiden. Anmeldelse af: Barry Eichengreen, »Hall of Mirrors. The Great Depression, the Great Recession and the Uses - ...

Assessing ESA on What It Is Designed For: A Reply to Cooper and Glaesser

Science.gov (United States)

Schneider, Carsten Q.; Wagemann, Claudius

2016-01-01

We appreciate Barry Cooper and Judith Glaesser's (henceforth CG) energy and effort put into reflecting on parts of our proposals laid out in "Set-theoretic Methods for the Social Sciences" (2012). We use our response to explain what enhanced standard analysis (ESA) is meant to achieve and what not, an issue about which CG hold erroneous…

A Response to Reviewer Comments Regarding the Manuscript, "Rule-Governed Behavior and Self-Control in Children with ADHD: A Theoretical Interpretation"

Science.gov (United States)

Barry, Leasha M.; Kelly, Melissa A.

2006-01-01

The authors appreciate the opportunity to respond to the issues raised in a review of the manuscript, "Rule-Governed Behavior and Self-Control in Children with ADHD: A Theoretical Interpretation" submitted by Leasha M. Barry and Melissa A. Kelly. Many of the points brought to light in the review are indeed useful for discussion and provide…

Targeting Master Regulators of the Breast Cancer Metastasis Transcriptome

Science.gov (United States)

2014-07-01

Medicine 3, 1-12. (featured article) PMCID: PMC3146366. 10. Luc G.T. Morris, Barry S. Taylor, Trever G. Bivona, Yongxing Gong, Stephanie Eng, Cameron...molecule STAT3 inhibitor LLL12. PLoS One 2012; 7: e35513. 43 Xu Q, Briggs J, Park S, Niu G, Kortylewski M, Zhang S et al. Targeting Stat3 blocks both

Identification of Bottlenecks and Capacity Constraints in F-14, F-15, F-16, and F/A-18 Aircraft Production.

Science.gov (United States)

1983-04-01

20319 Sa. ZEc ’-ASSIFICA7-ON DCVNORANG SCHEDULE ’S. DIS--iB ’Z-_N STA-EMEN t t’o ht. Report; UNLIMITED APPROVAL FOR PUBLIC RELEASE 01- U -N...Iustrial. Planni-. for a Surge in Military e; and. R-2360-AF. Santa Monica, Ca. : Rand, September 1979. 3. 3luestone, Barry, Jordan, Peter , ain Sullivan

Precision Near-Field Reconstruction in the Time Domain via Minimum Entropy for Ultra-High Resolution Radar Imaging

Directory of Open Access Journals (Sweden)

Jiwoong Yu

2017-05-01

Full Text Available Ultra-high resolution (UHR radar imaging is used to analyze the internal structure of objects and to identify and classify their shapes based on ultra-wideband (UWB signals using a vector network analyzer (VNA. However, radar-based imaging is limited by microwave propagation effects, wave scattering, and transmit power, thus the received signals are inevitably weak and noisy. To overcome this problem, the radar may be operated in the near-field. The focusing of UHR radar signals over a close distance requires precise geometry in order to accommodate the spherical waves. In this paper, a geometric estimation and compensation method that is based on the minimum entropy of radar images with sub-centimeter resolution is proposed and implemented. Inverse synthetic aperture radar (ISAR imaging is used because it is applicable to several fields, including medical- and security-related applications, and high quality images of various targets have been produced to verify the proposed method. For ISAR in the near-field, the compensation for the time delay depends on the distance from the center of rotation and the internal RF circuits and cables. Required parameters for the delay compensation algorithm that can be used to minimize the entropy of the radar images are determined so that acceptable results can be achieved. The processing speed can be enhanced by performing the calculations in the time domain without the phase values, which are removed after upsampling. For comparison, the parameters are also estimated by performing random sampling in the data set. Although the reduced data set contained only 5% of the observed angles, the parameter optimization method is shown to operate correctly.

Outcome of radioiodine therapy without, on or 3 days off carbimazole: a prospective interventional three-group comparison

International Nuclear Information System (INIS)

Walter, Martin A.; Christ-Crain, Mirjam; Mueller, Beat; Schindler, Christian; Mueller-Brand, Jan

2006-01-01

Carbimazole ameliorates hyperthyroidism but reduces radioiodine uptake and adversely affects the outcome of simultaneous radioiodine therapy. We explored whether withdrawal of carbimazole for 3 days can restore the outcome of radioiodine treatment without concurrent exacerbation of hyperthyroidism. By generating three groups with comparable radioiodine uptake, we also investigated whether the effect of carbimazole depends on the radioiodine uptake. Stratified by a radioiodine uptake >30%, 227 consecutive adult patients were prospectively assigned to radioiodine therapy (target dose 200 Gy) without, on or 3 days off carbimazole. Patients were clinically (Crooks-Wayne score) and biochemically (T 3 , fT 4 , TSH) followed up after 3, 6 and 12 months. Primary endpoint was outcome 12 months after radioiodine therapy. A total of 207 patients completed follow-up (toxic nodular goitre, n=117; Graves' disease, n=90). The overall success rate was 71.5%. Patients without and 3 days off carbimazole had similar biochemical (81.4% and 83.3%, respectively; p=0.82) and clinical outcomes [median (range) Crooks-Wayne score 0 (0-16) and 1 (0-10), respectively; p=0.73], which were both higher than in patients on carbimazole [42.6%, p 4 , T 3 and TSH. (orig.)

Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention.

LENUS (Irish Health Repository)

Flynn, Darran

2012-08-01

The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of young offenders one would expect to find a high prevalence of individuals with pre-psychotic or ultra-high risk mental states for psychosis (UHR). Accordingly young offender institutions offer an opportunity for early interventions which could result in improved long term mental health, social and legal outcomes. In the course of establishing a mental health in-reach service into Ireland\\'s only young offender prison, we sought to estimate unmet mental health needs.

Retraction: a descriptive study of a manual therapy intervention within a randomised controlled trial for hamstring and lower limb injury prevention

Directory of Open Access Journals (Sweden)

Hoskins Wayne

2011-10-01

Full Text Available Abstract The journal has been informed by its publisher BioMed Central that contrary to the statement in this article [Wayne Hoskins, Henry Pollard, Chiropractic & Osteopathy 2010, 18:23], they have been advised by the authors' institution Macquarie University, that its Human Research Ethics Committee did not approve this study. Because the study was conducted without institutional ethics committee approval it has been retracted.

Optimization of Fermentation Conditions for the Production of Bacteriocin Fermentate

Science.gov (United States)

2015-03-30

FERMENTATION CONDITIONS FOR THE PRODUCTION OF BACTERIOCIN “ FERMENTATE ” by Anthony Sikes Wayne Muller and Claire Lee March 2015...From - To) October 2010 – November 2013 4. TITLE AND SUBTITLE OPTIMIZATION OF FERMENTATION CONDITIONS FOR THE PRODUCTION OF BACTERIOCIN “ FERMENTATE ...nisin and pediocin. Whey + yeast extract was the best performing whey fermentation media. The nisin producer strain Lactococcus. lactis ssp. lactis was

Southeastern Virtual Institute for Health Equity and Wellness (SE VIEW)

Science.gov (United States)

2014-07-01

PA) for use by teachers Improved classroom health, education and physical activity Our healthy cooking , yoga and Deskercise videos were the... recipes and promoting the recipe book on a monthly basis since September.  El Informador as well as the Spanish radio station will make...Debra Hoy Perez, Annie E. Casey Foundation; Dr. Wayne A.I. Federick, Howard University; Dr. Yitades Gebre, Pan American Health Organization; Dr

The Advanced Surface Force Fleet: A Proposal for an Alternate Surface Force Structure and Its Impact in the Asian Pacific Theater

Science.gov (United States)

2015-12-01

also like to thank Captain Wayne P. Hughes Jr., Dr. Daniel Nussbaum, Dr. Fotis Papoulias, and Professor William Solitario, for their support...radical proposal is from the New Navy Fighting Machine 19 Stephen J. Hadley and William J. Perry, The...conduct HADR operations and to defeat an adversary in a maritime conflict are examined in Chapter IV and Chapter V, respectively. Chapter IV uses Cullen

Antibiotic-Resistant Enteric Bacteria in Environmental Waters

OpenAIRE

Lisa M. Casanova; Mark D. Sobsey

2016-01-01

Sources of antibiotic resistant organisms, including concentrated animal feeding operations (CAFOs), may lead to environmental surface and groundwater contamination with resistant enteric bacteria of public health concern. The objective of this research is to determine whether Salmonella, Escherichia coli, Yersinia enterocolitica, and enterococci resistant to clinically relevant antibiotics are present in surface and groundwater sources in two eastern North Carolina counties, Craven and Wayne...

Kas koostöö on vajadus või kohustus?

Index Scriptorium Estoniae

2008-01-01

15. nov. 2007 toimus Tallinnas turismi aastakonverents "Kas koostöö on vajadus või kohustus?". Ülevaade Maailma Turismiorganisatsiooni riski- ja kriisijuhtimise osakonna juhataja Dirk Glaesseri, Footprint Traveli juhi Jason Barry, MTÜ Maaturism juhatuse esimehe Varri Väli, Kaleva Travel Eesti tegevdirektori Merike Halliku, Riigikogu liikme Urmas Klaase, Eesti Kaubandus-Tööstuskoja teenuste direktori Merike Kompus van der Hoeveni ettekannetest

CDK5 A Novel Role in Prostate Cancer Immunotherapy

Science.gov (United States)

2016-10-01

Parallel: No scientific or budgetary overlap 90091646 (PI: Drake) Title: Enhancing Prostate Cancer Immunotherapy through Epigenetic Reprogramming for...Enhancing Prostate Cancer Immunotherapy through Epigenetic Reprogramming for Optimal Activation of Specific Effector T-Cells Time commitment: 1.2 calendar...AWARD NUMBER: W81XWH-15-1-0670 TITLE: CDK5-A Novel Role in Prostate Cancer Immunotherapy PRINCIPAL INVESTIGATOR: Dr. Barry Nelkin

On Paying Attention: Flagpoles, Mindfulness, and Teaching Writing

Science.gov (United States)

Kroll, Keith

2008-01-01

To pay attention--to observe, to see the richness and detail that is right before everyone--is the essence of mindfulness. It is also, the author argues, the essence of good writing--the kind of writing for which there is a long American tradition of writers such as Emerson, Thoreau, E. B. White, Barry Lopez, Annie Dillard, Joan Didion, John…

The association between client type and condom use with steady ...

African Journals Online (AJOL)

2011-08-03

Aug 3, 2011 ... experience a highly negative social stigma and face barri- ers to healthcare ... bile or outreach sites include workplace or home based counselling; vehicles .... Female. 3,034 (37.2). 620 (100.0). 4 (2.0). Male. 5,097 (62.7). 0 (0). 199 (98.0) ..... men who have sex with men, and barriers to condom use and HIV ...

Life After the George W. Bush Administration: A New US Strategy Towards China for Future Administrations

Science.gov (United States)

2008-05-15

Thucydides’ influence on political realism’s birth. 13 Barry Buzan, “The Timeless Wisdom of Realism?”, in International Theory: Positivism and Beyond...Leading Small Group (FALSG) Politburo 17 There are six xitongs: military affairs; legal affairs; administrative affairs; propaganda; united front...The Timeless Wisdom of Realism?.” Edited by Steve Smith, Ken Booth, and Marysia Zalewski. International Theory: Positivism and Beyond: 1996

Agriculture et environnement | Page 4 | CRDI - Centre de ...

International Development Research Centre (IDRC) Digital Library (Canada)

Les exigences des pays industrialisés en matière d'environnement, de santé et de salubrité sont parfois perçues, dans les pays en développement, comme des barrières non tarifaires au commerce. Cet ouvrage montre que de telles restrictions semblent se resserrer durant la saison où la production nationale est à son ...

Livres | Page 17 | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

Accountability of the International Monetary Fund. La question de la responsabilisation est au cœur du débat sur la réforme du FMI. Malheureusement, il s'agit d'un sujet pour lequel l'analyse est trop souvent entachée de jugements de valeur. Directeur(s) : Barry Carin et Angela Wood. Maison(s) d'édition : Ashgate, CRDI.