WorldWideScience

Sample records for barrier system features

  1. ENGINEERED BARRIER SYSTEM FEATURES, EVENTS AND PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    Jaros, W.

    2005-08-30

    The purpose of this report is to evaluate and document the inclusion or exclusion of engineered barrier system (EBS) features, events, and processes (FEPs) with respect to models and analyses used to support the total system performance assessment for the license application (TSPA-LA). A screening decision, either Included or Excluded, is given for each FEP along with the technical basis for exclusion screening decisions. This information is required by the U.S. Nuclear Regulatory Commission (NRC) at 10 CFR 63.114 (d, e, and f) [DIRS 173273]. The FEPs addressed in this report deal with those features, events, and processes relevant to the EBS focusing mainly on those components and conditions exterior to the waste package and within the rock mass surrounding emplacement drifts. The components of the EBS are the drip shield, waste package, waste form, cladding, emplacement pallet, emplacement drift excavated opening (also referred to as drift opening in this report), and invert. FEPs specific to the waste package, cladding, and drip shield are addressed in separate FEP reports: for example, ''Screening of Features, Events, and Processes in Drip Shield and Waste Package Degradation'' (BSC 2005 [DIRS 174995]), ''Clad Degradation--FEPs Screening Arguments (BSC 2004 [DIRS 170019]), and Waste-Form Features, Events, and Processes'' (BSC 2004 [DIRS 170020]). For included FEPs, this report summarizes the implementation of the FEP in the TSPA-LA (i.e., how the FEP is included). For excluded FEPs, this analysis provides the technical basis for exclusion from TSPA-LA (i.e., why the FEP is excluded). This report also documents changes to the EBS FEPs list that have occurred since the previous versions of this report. These changes have resulted due to a reevaluation of the FEPs for TSPA-LA as identified in Section 1.2 of this report and described in more detail in Section 6.1.1. This revision addresses updates in Yucca Mountain Project

  2. ENGINEERED BARRIER SYSTEM FEATURES, EVENTS, AND PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    na

    2005-05-30

    This analysis report is one of the technical reports containing documentation of the Environmental Radiation Model for Yucca Mountain, Nevada (ERMYN), a biosphere model supporting the total system performance assessment (TSPA) for the license application (LA) for the Yucca Mountain repository. This analysis report describes the development of biosphere dose conversion factors (BDCFs) for the volcanic ash exposure scenario, and the development of dose factors for calculating inhalation dose during volcanic eruption. A graphical representation of the documentation hierarchy for the ERMYN is presented in Figure 1 - 1. This figure shows the interrelationships among the products (i.e., analysis and model reports) developed for biosphere modeling and provides an understanding of how this analysis report contributes to biosphere modeling. This report is one of two reports that develop biosphere BDCFs, which are input parameters for the TSPA model. The ''Biosphere Model Report'' (BSC 2004 [DIRS 169460]) describes in detail the ERMYN conceptual model and mathematical model. The input parameter reports, shown to the right of the Biosphere Model Report in Figure 1-1, contain detailed descriptions of the model input parameters, their development and the relationship between the parameters and specific features, events and processes (FEPs). This report describes biosphere model calculations and their output, the BDCFs, for the volcanic ash exposure scenario. This analysis receives direct input from the outputs of the ''Biosphere Model Report'' (BSC 2004 [DIRS 169460]) and from the five analyses that develop parameter values for the biosphere model (BSC 2005 [DIRS 172827]; BSC 2004 [DIRS 169672]; BSC 2004 [DIRS 169673]; BSC 2004 [DIRS 169458]; and BSC 2004 [DIRS 169459]). The results of this report are further analyzed in the ''Biosphere Dose Conversion Factor Importance and Sensitivity Analysis'' (Figure 1 - 1). The

  3. Parallel Feature Extraction System

    Institute of Scientific and Technical Information of China (English)

    MAHuimin; WANGYan

    2003-01-01

    Very high speed image processing is needed in some application specially for weapon. In this paper, a high speed image feature extraction system with parallel structure was implemented by Complex programmable logic device (CPLD), and it can realize image feature extraction in several microseconds almost with no delay. This system design is presented by an application instance of flying plane, whose infrared image includes two kinds of feature: geometric shape feature in the binary image and temperature-feature in the gray image. Accordingly the feature extraction is taken on the two kind features. Edge and area are two most important features of the image. Angle often exists in the connection of the different parts of the target's image, which indicates that one area ends and the other area begins. The three key features can form the whole presentation of an image. So this parallel feature extraction system includes three processing modules: edge extraction, angle extraction and area extraction. The parallel structure is realized by a group of processors, every detector is followed by one route of processor, every route has the same circuit form, and works together at the same time controlled by a set of clock to realize feature extraction. The extraction system has simple structure, small volume, high speed, and better stability against noise. It can be used in the war field recognition system.

  4. Advanced thermal barrier coating systems

    Science.gov (United States)

    Dorfman, M. R.; Reardon, J. D.

    1985-01-01

    Current state-of-the-art thermal barrier coating (TBC) systems consist of partially stabilized zirconia coatings plasma sprayed over a MCrAlY bond coat. Although these systems have excellent thermal shock properties, they have shown themselves to be deficient for a number of diesel and aircraft applications. Two ternary ceramic plasma coatings are discussed with respect to their possible use in TBC systems. Zirconia-ceria-yttria (ZCY) coatings were developed with low thermal conductivities, good thermal shock resistance and improved resistance to vanadium containing environments, when compared to the baseline yttria stabilized zirconia (YSZ) coatings. In addition, dense zirconia-titania-yttria (ZTY) coatings were developed with particle erosion resistance exceeding conventional stabilized zirconia coatings. Both coatings were evaluated in conjunction with a NiCr-Al-Co-Y2O3 bond coat. Also, multilayer or hybrid coatings consisting of the bond coat with subsequent coatings of zirconia-ceria-yttria and zirconia-titania-yttria were evaluated. These coatings combine the enhanced performance characteristics of ZCY with the improved erosion resistance of ZTY coatings. Improvement in the erosion resistance of the TBC system should result in a more consistent delta T gradient during service. Economically, this may also translate into increased component life simply because the coating lasts longer.

  5. Systems study on engineered barriers: barrier performance analysis

    Energy Technology Data Exchange (ETDEWEB)

    Stula, R.T.; Albert, T.E.; Kirstein, B.E.; Lester, D.H.

    1980-09-01

    A performance assessment model for multiple barrier packages containing unreprocessed spent fuel has been modified and applied to several package designs. The objective of the study was to develop information to be used in programmatic decision making concerning engineered barrier package design and development. The assessment model, BARIER, was developed in previous tasks of the System Study on Engineered Barriers (SSEB). The new version discussed in this report contains a refined and expanded corrosion rate data base which includes pitting, crack growth, and graphitization as well as bulk corrosion. Corrosion rates for oxic and anoxic conditions at each of the two temperature ranges are supplied. Other improvements include a rigorous treatment of radionuclide release after package failure which includes resistance of damaged barriers and backfill, refined temperature calculations that account for convection and radiation, a subroutine to calculate nuclear gamma radiation field at each barrier surface, refined stress calculations with reduced conservatism and various coding improvements to improve running time and core usage. This report also contains discussion of alternative scenarios to the assumed flooded repository as well as the impact of water exclusion backfills. The model was used to assess post repository closure performance for several designs which were all variation of basic designs from the Spent Unreprocessed Fuel (SURF) program. Many designs were found to delay the onset of leaching by at least a few hundreds of years in all geologic media. Long delay times for radionuclide release were found for packages with a few inches of sorption backfill. Release of uranium, plutonium, and americium was assessed.

  6. Eco-nomics: Are the Planet-Unfriendly Features of Capitalism Barriers to Sustainability?

    Directory of Open Access Journals (Sweden)

    Merrill Singer

    2010-01-01

    Full Text Available This paper argues that there are essential features of capitalist modes of production, consumption, and waste dispersal in interaction with the environment and its built-in systemic features that contradict long-term sustainable development. These features include: (a contradictions in the origin and meaning of sustainability; (b the central role of the productivity ethic in capitalism and its reproduction in emergent green capitalism; (c the commodification of nature and the continued promotion of expanding consumption; (d globalism and the contradictions of continued Western-style development; and (e the emergence of anthropogenic ecocrises and crises interaction. In light of these barriers to capitalist sustainability, an alternative social narrative is needed, one that embraces values, understandings, and relationships that promote ecological stability and justice.

  7. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    R. Jarek

    2005-08-29

    The purpose of this model report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The resulting seepage evaporation and gas abstraction models are used in the total system performance assessment for the license application (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2005 [DIRS 173782], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports. To be consistent with other project documents that address features, events, and processes (FEPs), Table 6.14.1 of the current report includes updates to FEP numbers and FEP subjects for two FEPs identified in the technical work plan (TWP) governing this report (BSC 2005 [DIRS 173782]). FEP 2.1.09.06.0A (Reduction-oxidation potential in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.06.0B (Reduction-oxidation potential in Drifts; see Table 6.14-1). FEP 2.1.09.07.0A (Reaction kinetics in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.07.0B (Reaction kinetics in Drifts; see Table 6.14-1). These deviations from the TWP are justified because they improve integration with FEPs

  8. The Use of Feature Parameters to Asses Barrier Properties of ALD coatings for Flexible PV Substrates

    Science.gov (United States)

    Blunt, Liam; Robbins, David; Fleming, Leigh; Elrawemi, Mohamed

    2014-03-01

    This paper reports on the recent work carried out as part of the EU funded NanoMend project. The project seeks to develop integrated process inspection, cleaning, repair and control systems for nano-scale thin films on large area substrates. In the present study flexible photovoltaic films have been the substrate of interest. Flexible PV films are the subject of significant development at present and the latest films have efficiencies at or beyond the level of Si based rigid PV modules. These flexible devices are fabricated on polymer film by the repeated deposition, and patterning, of thin layer materials using roll-to-roll processes, where the whole film is approximately 3um thick prior to encapsulation. Whilst flexible films offer significant advantages in terms of mass and the possibility of building integration (BIPV) they are at present susceptible to long term environmental degradation as a result of water vapor transmission through the barrier layers to the CIGS (Copper Indium Gallium Selenide CuInxGa(1-x)Se2) PV cells thus causing electrical shorts and efficiency drops. Environmental protection of the GIGS cell is provided by a thin (40nm) barrier coating of Al2O3. The highly conformal aluminium oxide barrier layer is produced by atomic layer deposition (ALD) where, the ultra-thin Al2O3 layer is deposited onto polymer thin films before these films encapsulate the PV cell. The surface of the starting polymer film must be of very high quality in order to avoid creating defects in the device layers. Since these defects reduce manufacturing yield, in order to prevent them, a further thin polymer coating (planarization layer) is generally applied to the polymer film prior to deposition. The presence of surface irregularities on the uncoated film can create defects within the nanometre-scale, aluminium oxide, barrier layer and these are measured and characterised. This paper begins by reporting the results of early stage measurements conducted to characterise

  9. Brain barrier systems: a new frontier in metal neurotoxicological research

    OpenAIRE

    Zheng, Wei; Aschner, Michael; Ghersi-Egea, Jean-Francois

    2003-01-01

    The concept of brain barriers or a brain barrier system embraces the blood–brain interface, referred to as the blood–brain barrier, and the blood–cerebrospinal fluid (CSF) interface, referred to as the blood–CSF barrier. These brain barriers protect the CNS against chemical insults, by different complementary mechanisms. Toxic metal molecules can either bypass these mechanisms or be sequestered in and therefore potentially deleterious to brain barriers. Supportive evidence suggests that damag...

  10. Engineered Barrier System: Physical and Chemical Environment

    Energy Technology Data Exchange (ETDEWEB)

    P. Dixon

    2004-04-26

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports.

  11. Engineered Barrier System Degradation, Flow, and Transport Process Model Report

    Energy Technology Data Exchange (ETDEWEB)

    E.L. Hardin

    2000-07-17

    The Engineered Barrier System Degradation, Flow, and Transport Process Model Report (EBS PMR) is one of nine PMRs supporting the Total System Performance Assessment (TSPA) being developed by the Yucca Mountain Project for the Site Recommendation Report (SRR). The EBS PMR summarizes the development and abstraction of models for processes that govern the evolution of conditions within the emplacement drifts of a potential high-level nuclear waste repository at Yucca Mountain, Nye County, Nevada. Details of these individual models are documented in 23 supporting Analysis/Model Reports (AMRs). Nineteen of these AMRs are for process models, and the remaining 4 describe the abstraction of results for application in TSPA. The process models themselves cluster around four major topics: ''Water Distribution and Removal Model, Physical and Chemical Environment Model, Radionuclide Transport Model, and Multiscale Thermohydrologic Model''. One AMR (Engineered Barrier System-Features, Events, and Processes/Degradation Modes Analysis) summarizes the formal screening analysis used to select the Features, Events, and Processes (FEPs) included in TSPA and those excluded from further consideration. Performance of a potential Yucca Mountain high-level radioactive waste repository depends on both the natural barrier system (NBS) and the engineered barrier system (EBS) and on their interactions. Although the waste packages are generally considered as components of the EBS, the EBS as defined in the EBS PMR includes all engineered components outside the waste packages. The principal function of the EBS is to complement the geologic system in limiting the amount of water contacting nuclear waste. A number of alternatives were considered by the Project for different EBS designs that could provide better performance than the design analyzed for the Viability Assessment. The design concept selected was Enhanced Design Alternative II (EDA II).

  12. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    R. Jarek

    2004-11-23

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports.

  13. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    G.H. Nieder-Westermann

    2005-04-07

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports.

  14. SUBSURFACE BARRIER VALIDATION WITH THE SEAFACE SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Sandra Dalvit Dunn

    1997-11-30

    The overall objective of the effort was to develop and demonstrate an integrated methodology and field system to evaluate the integrity of in situ, impermeable barriers constructed in the vadose zone. An autonomous, remotely accessible, automatic monitoring and analysis system was designed and fabricated. It was thoroughly tested under field conditions, and was able to function as designed throughout the test period. Data inversion software was developed with enhanced capabilities over the previous prototype version, and integrated with the monitoring system for real time operation. Analytical simulations were performed to determine the inversion code's sensitivity to model parameters. Numerical simulations were performed to better understand how typical field conditions differ from the ideal model(s) which are used (or have been developed for use) in the inversion code and to further validate the flux limited forward model developed for use with the system. Results from the analytical and numerical assessment of the inversion code showed that the SEAtrace{trademark} approach could locate leaks within 0.4 to 1.2 m. Leak size determination was less accurate, but produced results within a factor of 3 to 8 for leaks in the 2.5 to 10 cm diameter range. The smallest engineered leak in the test 1.1 cm diameter, could be located but its size estimate was high by a factor of 30. Data analysis was performed automatically after each gas scan was completed, yielding results in less than thirty minutes, although the bulk of the results reported required post test data analysis to remove effects of high background concentrations. The field test of the integrated system was problematic, primarily due to unanticipated, unintentional leaks formed in the impermeable liner. The test facility constructed to proof the system was ambitious, initially having 11 engineered leaks of various dimensions that could be independently operated. While a great deal of care went into the

  15. Engineered Barrier System performance requirements systems study report. Revision 02

    Energy Technology Data Exchange (ETDEWEB)

    Balady, M.A.

    1997-01-14

    This study evaluates the current design concept for the Engineered Barrier System (EBS), in concert with the current understanding of the geologic setting to assess whether enhancements to the required performance of the EBS are necessary. The performance assessment calculations are performed by coupling the EBS with the geologic setting based on the models (some of which were updated for this study) and assumptions used for the 1995 Total System Performance Assessment (TSPA). The need for enhancements is determined by comparing the performance assessment results against the EBS related performance requirements. Subsystem quantitative performance requirements related to the EBS include the requirement to allow no more than 1% of the waste packages (WPs) to fail before 1,000 years after permanent closure of the repository, as well as a requirement to control the release rate of radionuclides from the EBS. The EBS performance enhancements considered included additional engineered components as well as evaluating additional performance available from existing design features but for which no performance credit is currently being taken.

  16. Article Including Environmental Barrier Coating System

    Science.gov (United States)

    Lee, Kang N. (Inventor)

    2015-01-01

    An enhanced environmental barrier coating for a silicon containing substrate. The enhanced barrier coating may include a bond coat doped with at least one of an alkali metal oxide and an alkali earth metal oxide. The enhanced barrier coating may include a composite mullite bond coat including BSAS and another distinct second phase oxide applied over said surface.

  17. Energy Dependence of the Fusion Barrier for Heavy Nuclear Systems

    Institute of Scientific and Technical Information of China (English)

    LIZhu-xia; WUXi-zhen; TIANJun-long; WANGNing

    2003-01-01

    The dynamical behavior of the fusion potential barrier for heavy nuclear systems is studied by means of the improved quantum molecular dynamics model. It is found that the fusion potential barrier experienced in a realistic fusion process (the dynamic fusion potential barrier) reduces with decrease of incident energies.

  18. Applications of barrier bucket RF systems at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, C.M.; /Fermilab

    2006-03-01

    In recent years, the barrier rf systems have become important tools in a variety of beam manipulation applications at synchrotrons. Four out of six proton synchrotrons at Fermilab are equipped with broad-band barrier rf systems. All of the beam manipulations pertaining to the longitudinal phase space in the Fermilab Recycler (synchrotron used for antiproton storage) are carried out using a barrier system. Recently, a number of new applications of barrier rf systems have been developed- the longitudinal momentum mining, longitudinal phase-space coating, antiproton stacking, fast bunch compression and more. Some of these techniques have been critical for the recent spectacular success of the collider performance at the Fermilab Tevatron. Barrier bunch coalescing to produce bright proton bunches has a high potential to increase proton antiproton luminosity significantly. In this paper, I will describe some of these techniques in detail. Finally, I make a few general remarks on issues related to barrier systems.

  19. International Collaboration Activities on Engineered Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-08-31

    The Used Fuel Disposition Campaign (UFDC) within the DOE Fuel Cycle Technologies (FCT) program has been engaging in international collaborations between repository R&D programs for high-level waste (HLW) disposal to leverage on gathered knowledge and laboratory/field data of near- and far-field processes from experiments at underground research laboratories (URL). Heater test experiments at URLs provide a unique opportunity to mimetically study the thermal effects of heat-generating nuclear waste in subsurface repository environments. Various configurations of these experiments have been carried out at various URLs according to the disposal design concepts of the hosting country repository program. The FEBEX (Full-scale Engineered Barrier Experiment in Crystalline Host Rock) project is a large-scale heater test experiment originated by the Spanish radioactive waste management agency (Empresa Nacional de Residuos Radiactivos S.A. – ENRESA) at the Grimsel Test Site (GTS) URL in Switzerland. The project was subsequently managed by CIEMAT. FEBEX-DP is a concerted effort of various international partners working on the evaluation of sensor data and characterization of samples obtained during the course of this field test and subsequent dismantling. The main purpose of these field-scale experiments is to evaluate feasibility for creation of an engineered barrier system (EBS) with a horizontal configuration according to the Spanish concept of deep geological disposal of high-level radioactive waste in crystalline rock. Another key aspect of this project is to improve the knowledge of coupled processes such as thermal-hydro-mechanical (THM) and thermal-hydro-chemical (THC) operating in the near-field environment. The focus of these is on model development and validation of predictions through model implementation in computational tools to simulate coupled THM and THC processes.

  20. Deployment Efficiency and Barrier Effectiveness Testing of a Temporary Anti-Personnel (TAP) Barrier System.

    Energy Technology Data Exchange (ETDEWEB)

    Allen, David James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hedrick, Charles D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Martinez, Ruben [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    This report documents tests conducted by Sandia National Laboratories (SNL) on behalf of the U.S. Department of State to evaluate a temporary anti-personnel (TAP) barrier system developed by Mitigation Technologies. For this, the SNL Denial and Structural Assessment department developed a test protocol for the evaluation of the TAP barrier system on the basis of deployment efficiency and barrier effectiveness against a riotous/mob attack threat. The test protocol was then executed by SNL personnel and the results of the testing are documented.

  1. Using Barriers to Reduce the Sensitivity to Edge Miscalculations of Casting-Based Object Projection Feature Estimation

    CERN Document Server

    Quesada, Luis

    2012-01-01

    3D motion tracking is a critical task in many computer vision applications. Unsupervised markerless 3D motion tracking systems determine the most relevant object in the screen and then track it by continuously estimating its projection features (center and area) from the edge image and a point inside the relevant object projection (namely, inner point), until the tracking fails. Existing reliable object projection feature estimation techniques are based on ray-casting or grid-filling from the inner point. These techniques assume the edge image to be accurate. However, in real case scenarios, edge miscalculations may arise from low contrast between the target object and its surroundings or motion blur caused by low frame rates or fast moving target objects. In this paper, we propose a barrier extension to casting-based techniques that mitigates the effect of edge miscalculations.

  2. Fluctuating Potential Barrier System with Correlated Spatial Noises

    Institute of Scientific and Technical Information of China (English)

    LI Jing-Hui

    2004-01-01

    In this paper, we study a fluctuating potential barrier system with correlated spatial noises. Study shows that for this system, there is the resonant activation over the fluctuating potential barrier, and that the correlation between the different spatial noises can enhance (or weaken) the resonant activation.

  3. Combustion chemical vapor desposited coatings for thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Hampikian, J.M.; Carter, W.B. [Georgia Institute of Technology, Atlanta, GA (United States)

    1995-10-01

    The new deposition process, combustion chemical vapor deposition, shows a great deal of promise in the area of thermal barrier coating systems. This technique produces dense, adherent coatings, and does not require a reaction chamber. Coatings can therefore be applied in the open atmosphere. The process is potentially suitable for producing high quality CVD coatings for use as interlayers between the bond coat and thermal barrier coating, and/or as overlayers, on top of thermal barrier coatings.

  4. Phonon tunneling through a double barrier system

    Energy Technology Data Exchange (ETDEWEB)

    Villegas, Diosdado [Departamento de Física, Universidad Central “Marta Abreu” de Las Villas, CP 54830, Santa Clara, Villa Clara (Cuba); Instituto de Física, Universidad Autónoma de Puebla, 18 Sur y San Claudio, Edif. 110A, Ciudad Universitaria, 72570 Puebla (Mexico); León-Pérez, Fernando de [Centro Universitario de la Defensa de Zaragoza, Ctra. de Huesca s/n, E-50090 Zaragoza (Spain); Pérez-Álvarez, R. [Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, CP 62209 Cuernavaca (Mexico); Arriaga, J., E-mail: arriaga@ifuap.buap.mx [Instituto de Física, Universidad Autónoma de Puebla, 18 Sur y San Claudio, Edif. 110A, Ciudad Universitaria, 72570 Puebla (Mexico)

    2015-04-15

    The tunneling of optical and acoustic phonons at normal incidence on a double-barrier is studied in this paper. Transmission coefficients and resonance conditions are derived theoretically under the assumption that the long-wavelength approximation is valid. It is shown that the behavior of the transmission coefficients for the symmetric double barrier has a Lorentzian form close to resonant frequencies and that Breit–Wigner's formula have a general validity in one-dimensional phonon tunneling. Authors also study the so-called generalized Hartman effect in the tunneling of long-wavelength phonons and show that this effect is a numerical artifact resulting from taking the opaque limit before exploring the variation with a finite barrier width. This study could be useful for the design of acoustic devices.

  5. Fabrication of metallic single electron transistors featuring plasma enhanced atomic layer deposition of tunnel barriers

    Science.gov (United States)

    Karbasian, Golnaz

    The continuing increase of the device density in integrated circuits (ICs) gives rise to the high level of power that is dissipated per unit area and consequently a high temperature in the circuits. Since temperature affects the performance and reliability of the circuits, minimization of the energy consumption in logic devices is now the center of attention. According to the International Technology Roadmaps for Semiconductors (ITRS), single electron transistors (SETs) hold the promise of achieving the lowest power of any known logic device, as low as 1x10-18 J per switching event. Moreover, SETs are the most sensitive electrometers to date, and are capable of detecting a fraction of an electron charge. Despite their low power consumption and high sensitivity for charge detection, room temperature operation of these devices is quite challenging mainly due to lithographical constraints in fabricating structures with the required dimensions of less than 10 nm. Silicon based SETs have been reported to operate at room temperature. However, they all suffer from significant variation in batch-to-batch performance, low fabrication yield, and temperature-dependent tunnel barrier height. In this project, we explored the fabrication of SETs featuring metal-insulator-metal (MIM) tunnel junctions. While Si-based SETs suffer from undesirable effect of dopants that result in irregularities in the device behavior, in metal-based SETs the device components (tunnel barrier, island, and the leads) are well-defined. Therefore, metal SETs are potentially more predictable in behavior, making them easier to incorporate into circuits, and easier to check against theoretical models. Here, the proposed fabrication method takes advantage of unique properties of chemical mechanical polishing (CMP) and plasma enhanced atomic layer deposition (PEALD). Chemical mechanical polishing provides a path for tuning the dimensions of the tunnel junctions, surpassing the limits imposed by electron beam

  6. John H. Chafee Coastal Barrier Resources System Approximate Polygons

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Coastal Barrier Resources System (CBRS) data set, produced by the U.S. Fish and Wildlife Service (Service), contains areas designated as undeveloped coastal...

  7. Palmprint Based Verification System Using SURF Features

    Science.gov (United States)

    Srinivas, Badrinath G.; Gupta, Phalguni

    This paper describes the design and development of a prototype of robust biometric system for verification. The system uses features extracted using Speeded Up Robust Features (SURF) operator of human hand. The hand image for features is acquired using a low cost scanner. The palmprint region extracted is robust to hand translation and rotation on the scanner. The system is tested on IITK database of 200 images and PolyU database of 7751 images. The system is found to be robust with respect to translation and rotation. It has FAR 0.02%, FRR 0.01% and accuracy of 99.98% and can be a suitable system for civilian applications and high-security environments.

  8. Effect of joint mechanism on vehicle redirectional capability of water-filled road safety barrier systems.

    Science.gov (United States)

    Thiyahuddin, M I; Thambiratnam, D P; Gu, Y T

    2014-10-01

    Portable water-filled barriers (PWFBs) are roadside appurtenances that prevent vehicles from penetrating into temporary construction zones on roadways. PWFBs are required to satisfy the strict regulations for vehicle re-direction in tests. However, many of the current PWFBs fail to re-direct the vehicle at high speeds due to the inability of the joints to provide appropriate stiffness. The joint mechanism hence plays a crucial role in the performance of a PWFB system at high speed impacts. This paper investigates the desired features of the joint mechanism in a PWFB system that can re-direct vehicles at high speeds, while limiting the lateral displacement to acceptable limits. A rectangular "wall" representative of a 30m long barrier system was modeled and a novel method of joining adjacent road barriers was introduced through appropriate pin-joint connections. The impact response of the barrier "wall" and the vehicle was obtained and the results show that a rotational stiffness of 3000kNm/rad at the joints seems to provide the desired features of the PWFB system to re-direct impacting vehicles and restrict the lateral deflection. These research findings will be useful to safety engineers and road barrier designers in developing a new generation of PWFBs for increased road safety.

  9. On the effects of preferential or barrier flow features on solute plumes in permeable porous media

    Science.gov (United States)

    Sebben, Megan L.; Werner, Adrian D.

    2016-12-01

    Despite that discrete flow features (DFFs, e.g. fractures and faults) are common features in the subsurface, few studies have explored the influence of DFFs on solute plumes in otherwise permeable rocks (e.g. sandstone, limestone), compared to low-permeability rock settings (e.g. granite and basalt). DFFs can provide preferential flow pathways (i.e. 'preferential flow features'; PFFs), or can act to impede flow (i.e. 'barrier flow features'; BFFs). This research uses a simple analytical expression and numerical modelling to explore how a single DFF influences the steady-state distributions of solute plumes in permeable aquifers. The analysis quantifies the displacement and widening (or narrowing) of a steady-state solute plume as it crosses a DFF in idealised, 1 × 1 m moderately permeable rock aquifers. Previous research is extended by accounting for DFFs as 2D flow features, and including BFF situations. A range of matrix-DFF permeability ratios (0.01 to 100) and DFF apertures (0.25 mm to 2 cm), typical of sedimentary aquifers containing medium-to-large fractures, are considered. The results indicate that for the conceptual models considered here, PFFs typically have a more significant influence on plume distributions than BFFs, and the impact of DFFs on solute plumes generally increases with increasing aperture. For example, displacement of peak solute concentration caused by DFFs exceeds 20 cm in some PFF cases, compared to a maximum of 0.64 cm in BFF cases. PFFs widen plumes up to 9.7 times, compared to a maximum plume widening of 2.0 times in BFF cases. Plumes crossing a PFF are less symmetrical, and peak solute concentrations beneath PFFs are up to two orders of magnitude lower than plumes in BFF cases. This study extends current knowledge of the attenuating influence of DFFs in otherwise permeable rocks on solute plume characteristics, through evaluation of 2D flow effects in DFFs for a variety of DFF apertures, and by considering BFF situations.

  10. Automatic Melody Generation System with Extraction Feature

    Science.gov (United States)

    Ida, Kenichi; Kozuki, Shinichi

    In this paper, we propose the melody generation system with the analysis result of an existing melody. In addition, we introduce the device that takes user's favor in the system. The melody generation is done by pitch's being arranged best on the given rhythm. The best standard is decided by using the feature element extracted from existing music by proposed method. Moreover, user's favor is reflected in the best standard by operating some of the feature element in users. And, GA optimizes the pitch array based on the standard, and achieves the system.

  11. Combustion chemical vapor deposited coatings for thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Hampikian, J.M.; Carter, W.B. [Georgia Institute of Technology, Atlanta, GA (United States). School of Materials Science and Engineering

    1995-12-31

    The new deposition process, combustion chemical vapor deposition, shows a great deal of promise in the area of thermal barrier coating systems. This technique produces dense, adherent coatings, and does not require a reaction chamber. Coatings can therefore be applied in the open atmosphere. The process is potentially suitable for producing high quality CVD coatings for use as interlayers between the bond coat and thermal barrier coating, and/or as overlayers, on top of thermal barrier coatings. In this report, the evaluation of alumina and ceria coatings on a nickel-chromium alloy is described.

  12. Statistical feature extraction based iris recognition system

    Indian Academy of Sciences (India)

    ATUL BANSAL; RAVINDER AGARWAL; R K SHARMA

    2016-05-01

    Iris recognition systems have been proposed by numerous researchers using different feature extraction techniques for accurate and reliable biometric authentication. In this paper, a statistical feature extraction technique based on correlation between adjacent pixels has been proposed and implemented. Hamming distance based metric has been used for matching. Performance of the proposed iris recognition system (IRS) has been measured by recording false acceptance rate (FAR) and false rejection rate (FRR) at differentthresholds in the distance metric. System performance has been evaluated by computing statistical features along two directions, namely, radial direction of circular iris region and angular direction extending from pupil tosclera. Experiments have also been conducted to study the effect of number of statistical parameters on FAR and FRR. Results obtained from the experiments based on different set of statistical features of iris images show thatthere is a significant improvement in equal error rate (EER) when number of statistical parameters for feature extraction is increased from three to six. Further, it has also been found that increasing radial/angular resolution,with normalization in place, improves EER for proposed iris recognition system

  13. The role of plants on isolation barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Link, S.O.; Downs, J.L. [Pacific Northwest Lab., Richland, WA (United States); Waugh, W.J. [UNC Chem-Nuclear Geotech, Grand Junction, CO (United States)

    1994-11-01

    Surface barriers are used to isolate buried wastes from the environment. Most have been built for short-term isolation. The need to isolate radioactive wastes from the environment requires that the functional integrity of a barrier be maintained for thousands of years. Barrier function strongly depends on vegetation. Plants reduce wind and water erosion and minimize drainage, but may transport contaminants if roots extend into buried wastes. Our review of the function of plants on surface barriers focuses on the role of plants across mesic to arid environments and gives special consideration to studies done at Hanford. The Hanford Barrier Development Program was created to design and test an earthen cover system to inhibit water infiltration, plant and animal intrusion, and wind and water erosion, while isolating buried wastes for at least 1000 years. Studies at the Hanford have shown that plants will significantly interact with the barrier. Plants transpire soil water back into the atmosphere. Deep-rooted perennials best recycle water; soil water may drain through the root zone of shallow-rooted annuals. Lysimeter studies indicate that a surface layer of fine soil with deep-rooted plants precludes drainage even with three times normal precipitation. The presence of vegetation greatly reduces water and wind erosion, but deep-rooted plants pose a threat of biointrusion and contaminant transport. The Hanford barrier includes a buried rock layer and asphalt layer to prevent biointrusion.

  14. DAB: Multiplex and system support features

    Science.gov (United States)

    Riley, J. L.

    This Report describes the multiplex and system support features of the Eureka 147/DAB digital audio system. It sets out the requirements of all users along the broadcast chain from service providers and broadcaster through to the listener. The contents of the transmission frame are examined drawing the distinction between the main service multiplex and the provision of control information in a separate fast data channel. The concept of the DAB service structure is introduced and the inherent system flexibility for altering the service arrangement is explained. A wide range of service information features builds on those provided in earlier systems, such as RDS (Radio Data System) and is intended to make it easier for a listener to find any required service and to add a further dimension to audio broadcasting. The choices available to users in all of these areas are examined.

  15. Subsurface barrier validation with the SEAtrace{trademark} system

    Energy Technology Data Exchange (ETDEWEB)

    Sandra Dalvit Dunn; William Lowry; Veraun Chipman

    1999-09-01

    Under contract to the Department of Energy, Science and Engineering Associates has completed development and testing of a subsurface barrier verification and monitoring system. This system, called SEAtrace{trademark}, is able to locate and size leaks with a high degree of accuracy in subsurface barriers that are emplaced in an unsaturated medium. It uses gaseous tracer injection, in-field real-time monitoring, and real time data analysis to evaluate barrier integrity. The approach is: Conservative as it measures vapor leaks in a containment system whose greatest risk is posed by liquid leaks; Applicable to any impermeable type of barrier emplacement technology in the unsaturated zone; Inexpensive as it uses readily available, non-toxic, nonhazardous gaseous tracers, does not require an inordinately large number of sampling points, and injection and sampling points can be emplaced by direct push techniques; Capable of assessing not only a barrier's initial integrity, but can also provide long-term monitoring. To date, six demonstrations of the system have been completed. Results from two of the demonstrations are detailed in this report. They include the final developmental demonstration of the SEAtrace system and a comparison demonstration of two tracer based verification technologies. The final developmental demonstration of SEAtrace was completed at a naval facility in Brunswick, Maine. The demonstration was funded solely by the DOE and was performed in cooperation with the US Navy, the Environmental Protection Agency, and the Maine Department of Environmental Protection.

  16. Microstructural Evolution and interfacial motion in systems with diffusion barriers

    Energy Technology Data Exchange (ETDEWEB)

    Perry H. Leo

    2009-03-05

    This research program was designed to model and simulate phase transformations in systems containing diffusion barriers. The modeling work included mass flow, phase formation, and microstructural evolution in interdiffusing systems. Simulation work was done by developing Cahn-Hilliard and phase field equations governing both the temporal and spatial evolution of the composition and deformation fields and other important phase variables.

  17. Fingerprint matching system using Level 3 features

    Directory of Open Access Journals (Sweden)

    Prince

    2010-06-01

    Full Text Available Fingerprint biometric security system identifies the unique property in human being and matching with template stored in database. Fingerprint details are generally defined in three levels i.e. Level 1 (Pattern, Level 2(Minutiae points and Level 3 (pores and contour ridges. Level 3 features are barely used by automated fingerprintverification system. This research paper presents a Level 3 ingerprint matching system. In this paper, we deal with pores for matching with template. With the local pore model, a SIFT algorithm is used to match the pores with template. Experiments on a good quality fingerprint dataset are performed and the results demonstrate that the proposed Level 3 features matching model performed more accurately and robustly.

  18. Special feature on imaging systems and techniques

    Science.gov (United States)

    Yang, Wuqiang; Giakos, George

    2013-07-01

    The IEEE International Conference on Imaging Systems and Techniques (IST'2012) was held in Manchester, UK, on 16-17 July 2012. The participants came from 26 countries or regions: Austria, Brazil, Canada, China, Denmark, France, Germany, Greece, India, Iran, Iraq, Italy, Japan, Korea, Latvia, Malaysia, Norway, Poland, Portugal, Sweden, Switzerland, Taiwan, Tunisia, UAE, UK and USA. The technical program of the conference consisted of a series of scientific and technical sessions, exploring physical principles, engineering and applications of new imaging systems and techniques, as reflected by the diversity of the submitted papers. Following a rigorous review process, a total of 123 papers were accepted, and they were organized into 30 oral presentation sessions and a poster session. In addition, six invited keynotes were arranged. The conference not only provided the participants with a unique opportunity to exchange ideas and disseminate research outcomes but also paved a way to establish global collaboration. Following the IST'2012, a total of 55 papers, which were technically extended substantially from their versions in the conference proceeding, were submitted as regular papers to this special feature of Measurement Science and Technology . Following a rigorous reviewing process, 25 papers have been finally accepted for publication in this special feature and they are organized into three categories: (1) industrial tomography, (2) imaging systems and techniques and (3) image processing. These papers not only present the latest developments in the field of imaging systems and techniques but also offer potential solutions to existing problems. We hope that this special feature provides a good reference for researchers who are active in the field and will serve as a catalyst to trigger further research. It has been our great pleasure to be the guest editors of this special feature. We would like to thank the authors for their contributions, without which it would

  19. Low temperature monitoring system for subsurface barriers

    Science.gov (United States)

    Vinegar, Harold J.; McKinzie, II. Billy John

    2009-08-18

    A system for monitoring temperature of a subsurface low temperature zone is described. The system includes a plurality of freeze wells configured to form the low temperature zone, one or more lasers, and a fiber optic cable coupled to at least one laser. A portion of the fiber optic cable is positioned in at least one freeze well. At least one laser is configured to transmit light pulses into a first end of the fiber optic cable. An analyzer is coupled to the fiber optic cable. The analyzer is configured to receive return signals from the light pulses.

  20. Origin of Small Barriers in Jahn–Teller Systems

    DEFF Research Database (Denmark)

    Barriuso, M. T.; Ortiz-Sevilla, B.; Aramburu, J. A.

    2013-01-01

    Despite its relevance, the microscopic origin of the energy barrier, B, between the compressed and elongated geometries of Jahn–Teller (JT) systems is not well understood yet because of a lack of quantitative data about its various contributions. Seeking to clear up this matter, we have carried o...

  1. Experimental Study on Spiral Patterns in Dielectric Barrier Discharge System

    Institute of Scientific and Technical Information of China (English)

    LIU Shu-Hua; DONG Li-Fang; LIU Fu-Cheng; LI Shu-Feng; LI Xue-Chen; WANG Hong-Fang

    2006-01-01

    Spiral patterns are obtained in a dielectric barrier discharge system with water electrodes. The dynamics of spiral formation and transition is investigated. Wavelength characteristic of spiral patterns is also studied. Correlation measurements indicate that the wavelength of spiral pattern increases with the increasing gas gap width and oscillates with the increasing drive frequency.

  2. Microstructural features and properties of plasma sprayed YPSZ/NiCrAlY thermal barrier coating (TBC)

    Institute of Scientific and Technical Information of China (English)

    孙大谦; 王文权; 宣兆志; 宫文彪

    2004-01-01

    The plasma sprayed thermal barrier coating (TBC) consists of NiCrAlY bond coating and yttria partially stabilized zirconia (YPSZ) top coating. NiCrAlY coating mainly contains Ni solid solution with face centered cubic lattice, Al2O3 oxides and pores. The most obvious feature of YPSZ coating with tetragonal zirconia is a lot of vertical microcracks in this coating. The thermal insulation capability of the TBC increased with an increase in YPSZ coating thickness, the temperature drop across the TBC increasing from 60℃ to 92℃ with increasing YPSZ coating thickness with increasing YPSZ coating thickness and cracks initiated mainly in original vertical microcrack tips of the YPSZ coating and propagated not only along YPSZ coating / NiCrAlY coating interface but also through into two stages: transient oxidation stage with rapid oxidation rate and steady oxidation stage with slow oxidation. Their transition time was favorable to increase YPSZ coating toughness and to decrease the pores and oxides of the TBC system for improving thermal shock resistance and oxidation resistance of the TBC.

  3. CULTURAL FEATURES SHARED BY INFORMATION SYSTEMS USERS

    Directory of Open Access Journals (Sweden)

    Marilena Maldonado

    2006-11-01

    Full Text Available Problems may arise when organizational culture is not considered in the development of information systems, such as difficulties in system implementation, since users do not accept changes in their work cultures. However, current methodology designs do not contemplate cultural factors. The objective of this investigation was to identify the main cultural features shared by the users of information systems in an Argentinean university. As result of this work it was possible to identify the memes shared by the members of the community selected, and to categorize such memes according to their incidence grade. This work seeks to be an initial step towards the construction of systems that evolve along with the organizational culture they are an integral part of.

  4. Horizontal flow barriers for the transient ground-water flow model, Death Valley regional ground-water flow system, Nevada and California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the surface traces of regional features simulated as horizontal flow barriers in the Death Valley regional ground-water flow system...

  5. Features, Events, and Processes: system Level

    Energy Technology Data Exchange (ETDEWEB)

    D. McGregor

    2004-10-15

    The purpose of this analysis report is to evaluate and document the inclusion or exclusion of the system-level features, events, and processes (FEPs) with respect to modeling used to support the total system performance assessment for the license application (TSPA-LA). A screening decision, either Included or Excluded, is given for each FEP along with the technical basis for screening decisions. This information is required by the U.S. Nuclear Regulatory Commission (NRC) at 10 CFR 63.113 (d, e, and f) (DIRS 156605). The system-level FEPs addressed in this report typically are overarching in nature, rather than being focused on a particular process or subsystem. As a result, they are best dealt with at the system level rather than addressed within supporting process-level or subsystem-level analyses and models reports. The system-level FEPs also tend to be directly addressed by regulations, guidance documents, or assumptions listed in the regulations; or are addressed in background information used in development of the regulations. For included FEPs, this analysis summarizes the implementation of the FEP in the TSPA-LA (i.e., how the FEP is included). For excluded FEPs, this analysis provides the technical basis for exclusion from the TSPA-LA (i.e., why the FEP is excluded). The initial version of this report (Revision 00) was developed to support the total system performance assessment for site recommendation (TSPA-SR). This revision addresses the license application (LA) FEP List (DIRS 170760).

  6. Engineered Barrier System: Physical and Chemical Environment Model

    Energy Technology Data Exchange (ETDEWEB)

    D. M. Jolley; R. Jarek; P. Mariner

    2004-02-09

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports.

  7. Diffusion Barrier Coating System and Oxidation Behavior of Coated Alloys

    Institute of Scientific and Technical Information of China (English)

    T.NARITA

    2009-01-01

    @@ 1 Introduction Research into the formation of Re-based alloys is in progress in our laboratory to provide a diffusion barrier layer between heat-resistant alloys and Al reservoir layers, which assist in the formation and maintenance a protective Al2O3 scale for long periods. Coatings with a two-layered structure comprised of inner Re-based alloy layer and outer β-NiAl layer with or without Pt addition were successfully formed on various heat resistant alloys such as Ni-based singlecrystal superalloys, Ni-based heat resistant alloys, NiMo based alloy, Ni-Cr based alloy, and Fe-based alloys. The duplex layer coating proposed is generally termed a diffusion barrier coating system; DBC system.

  8. A preliminary experimental study on virtual sound barrier system

    Science.gov (United States)

    Zou, Haishan; Qiu, Xiaojun; Lu, Jing; Niu, Feng

    2007-10-01

    Virtual sound barrier (VSB) is an array of loudspeakers and microphones forming an acoustic barrier, which creates a quiet zone without blocking air and light. A 16-channel cylindrical VSB system has been developed and its feasibility is verified by both numerical simulations and experiments. Experimental results in a normal room show that it can create a quiet zone larger than the size of a human head in the low-middle frequency, with a total sound pressure level reduction of more than 10 dB in the quiet zone. The control performance of the system with respect to the frequency, the distribution of the error sensors and the control sources are discussed.

  9. Thermal and Environmental Barrier Coatings for Advanced Propulsion Engine Systems

    Science.gov (United States)

    Zhu, Dong-Ming; Miller, Robert A.

    2004-01-01

    Ceramic thermal and environmental barrier coatings (TEBCs) are used in gas turbine engines to protect engine hot-section components in the harsh combustion environments, and extend component lifetimes. For future high performance engines, the development of advanced ceramic barrier coating systems will allow these coatings to be used to simultaneously increase engine operating temperature and reduce cooling requirements, thereby leading to significant improvements in engine power density and efficiency. In order to meet future engine performance and reliability requirements, the coating systems must be designed with increased high temperature stability, lower thermal conductivity, and improved thermal stress and erosion resistance. In this paper, ceramic coating design and testing considerations will be described for high temperature and high-heat-flux engine applications in hot corrosion and oxidation, erosion, and combustion water vapor environments. Further coating performance and life improvements will be expected by utilizing advanced coating architecture design, composition optimization, and improved processing techniques, in conjunction with modeling and design tools.

  10. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2014-04-01

    This project (10/01/2010-9/30/2014), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This project will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. In this project, the focus is to develop and implement novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; perform material characterizations and oxidation/corrosion tests; and demonstrate our new thermal barrier coating (TBC) systems experimentally under integrated gasification combined cycle (IGCC) environments.

  11. Complex systems: features, similarity and connectivity

    CERN Document Server

    Comin, Cesar H; Silva, Filipi N; Amancio, Diego R; Rodrigues, Francisco A; Costa, Luciano da F

    2016-01-01

    The increasing interest in complex networks research has been a consequence of several intrinsic features of this area, such as the generality of the approach to represent and model virtually any discrete system, and the incorporation of concepts and methods deriving from many areas, from statistical physics to sociology, which are often used in an independent way. Yet, for this same reason, it would be desirable to integrate these various aspects into a more coherent and organic framework, which would imply in several benefits normally allowed by the systematization in science, including the identification of new types of problems and the cross-fertilization between fields. More specifically, the identification of the main areas to which the concepts frequently used in complex networks can be applied paves the way to adopting and applying a larger set of concepts and methods deriving from those respective areas. Among the several areas that have been used in complex networks research, pattern recognition, op...

  12. A Bayesian network approach to predicting nest presence of thefederally-threatened piping plover (Charadrius melodus) using barrier island features

    Science.gov (United States)

    Gieder, Katherina D.; Karpanty, Sarah M.; Frasera, James D.; Catlin, Daniel H.; Gutierrez, Benjamin T.; Plant, Nathaniel G.; Turecek, Aaron M.; Thieler, E. Robert

    2014-01-01

    Sea-level rise and human development pose significant threats to shorebirds, particularly for species that utilize barrier island habitat. The piping plover (Charadrius melodus) is a federally-listed shorebird that nests on barrier islands and rapidly responds to changes in its physical environment, making it an excellent species with which to model how shorebird species may respond to habitat change related to sea-level rise and human development. The uncertainty and complexity in predicting sea-level rise, the responses of barrier island habitats to sea-level rise, and the responses of species to sea-level rise and human development necessitate a modelling approach that can link species to the physical habitat features that will be altered by changes in sea level and human development. We used a Bayesian network framework to develop a model that links piping plover nest presence to the physical features of their nesting habitat on a barrier island that is impacted by sea-level rise and human development, using three years of data (1999, 2002, and 2008) from Assateague Island National Seashore in Maryland. Our model performance results showed that we were able to successfully predict nest presence given a wide range of physical conditions within the model’s dataset. We found that model predictions were more successful when the range of physical conditions included in model development was varied rather than when those physical conditions were narrow. We also found that all model predictions had fewer false negatives (nests predicted to be absent when they were actually present in the dataset) than false positives (nests predicted to be present when they were actually absent in the dataset), indicating that our model correctly predicted nest presence better than nest absence. These results indicated that our approach of using a Bayesian network to link specific physical features to nest presence will be useful for modelling impacts of sea-level rise- or human

  13. TRITIUM BARRIER MATERIALS AND SEPARATION SYSTEMS FOR THE NGNP

    Energy Technology Data Exchange (ETDEWEB)

    Sherman, S; Thad Adams, T

    2008-07-17

    Contamination of downstream hydrogen production plants or other users of high-temperature heat is a concern of the Next Generation Nuclear Plant (NGNP) Project. Due to the high operating temperatures of the NGNP (850-900 C outlet temperature), tritium produced in the nuclear reactor can permeate through heat exchangers to reach the hydrogen production plant, where it can become incorporated into process chemicals or the hydrogen product. The concentration limit for tritium in the hydrogen product has not been established, but it is expected that any future limit on tritium concentration will be no higher than the air and water effluent limits established by the NRC and the EPA. A literature survey of tritium permeation barriers, capture systems, and mitigation measures is presented and technologies are identified that may reduce the movement of tritium to the downstream plant. Among tritium permeation barriers, oxide layers produced in-situ may provide the most suitable barriers, though it may be possible to use aluminized surfaces also. For tritium capture systems, the use of getters is recommended, and high-temperature hydride forming materials such as Ti, Zr, and Y are suggested. Tritium may also be converted to HTO in order to capture it on molecular sieves or getter materials. Counter-flow of hydrogen may reduce the flux of tritium through heat exchangers. Recommendations for research and development work are provided.

  14. Implementation of electronic data capture systems: barriers and solutions.

    Science.gov (United States)

    Welker, James A

    2007-05-01

    Although increasing in pace, the conversion to Electronic Data Capture (EDC) has been a slow progression. The use of EDC systems should confer improved data integrity, cost savings and a shorter time to study database closure. This will reduce the time to market and cost of new medications. With the current sentiment of the industry suggesting the cost analysis has been accepted to be in favor of EDC, the likely limitation to disseminated use is an inability to implement these systems. If the leadership at the sponsor, clinical research organization and investigator site is cognizant of the barriers to implementation, they can anticipate and mitigate them prior to the users becoming disgruntled and resistant to the new method of data capture. Once understood, barriers such as user input, technical support, user motivation, regulatory requirements, communication with users, timing of implementation, software installation, graphical user interface, identification of bridgers, patient participation, availability of technology, and costs can be better addressed at the beginning of the implementation process and successfully averted. This review discusses these barriers and potential solutions that can assist the clinical trial industry in achieving more wide-spread EDC use and the resulting improvement in operating efficiencies.

  15. Computational design and experimental validation of new thermal barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin [Louisiana State Univ., Baton Rouge, LA (United States)

    2015-03-31

    The focus of this project is on the development of a reliable and efficient ab initio based computational high temperature material design method which can be used to assist the Thermal Barrier Coating (TBC) bond-coat and top-coat design. Experimental evaluations on the new TBCs are conducted to confirm the new TBCs’ properties. Southern University is the subcontractor on this project with a focus on the computational simulation method development. We have performed ab initio density functional theory (DFT) method and molecular dynamics simulation on screening the top coats and bond coats for gas turbine thermal barrier coating design and validation applications. For experimental validations, our focus is on the hot corrosion performance of different TBC systems. For example, for one of the top coatings studied, we examined the thermal stability of TaZr2.75O8 and confirmed it’s hot corrosion performance.

  16. Protection against malevolent use of vehicles at Nuclear Power Plants. Vehicle barrier system selection guidance

    Energy Technology Data Exchange (ETDEWEB)

    Nebuda, D.T.

    1994-08-01

    This manual provides a simplified procedure for selecting land vehicle barriers that will stop the design basis vehicle threat adopted by the U.S. Nuclear Regulatory Commission. Proper selection and construction of vehicle barriers should prevent intrusion of the design basis vehicle. In addition, vital safety related equipment should survive a design basis vehicle bomb attack when vehicle barriers are properly selected, sited, and constructed. This manual addresses passive vehicle barriers, active vehicle barriers, and site design features that can be used to reduce vehicle impact velocity.

  17. Towards a barrier height benchmark set for biologically relevant systems

    Directory of Open Access Journals (Sweden)

    Jimmy C. Kromann

    2016-05-01

    Full Text Available We have collected computed barrier heights and reaction energies (and associated model structures for five enzymes from studies published by Himo and co-workers. Using this data, obtained at the B3LYP/6- 311+G(2d,2p[LANL2DZ]//B3LYP/6-31G(d,p level of theory, we then benchmark PM6, PM7, PM7-TS, and DFTB3 and discuss the influence of system size, bulk solvation, and geometry re-optimization on the error. The mean absolute differences (MADs observed for these five enzyme model systems are similar to those observed for PM6 and PM7 for smaller systems (10–15 kcal/mol, while DFTB results in a MAD that is significantly lower (6 kcal/mol. The MADs for PMx and DFTB3 are each dominated by large errors for a single system and if the system is disregarded the MADs fall to 4–5 kcal/mol. Overall, results for the condensed phase are neither more or less accurate relative to B3LYP than those in the gas phase. With the exception of PM7-TS, the MAD for small and large structural models are very similar, with a maximum deviation of 3 kcal/mol for PM6. Geometry optimization with PM6 shows that for one system this method predicts a different mechanism compared to B3LYP/6-31G(d,p. For the remaining systems, geometry optimization of the large structural model increases the MAD relative to single points, by 2.5 and 1.8 kcal/mol for barriers and reaction energies. For the small structural model, the corresponding MADs decrease by 0.4 and 1.2 kcal/mol, respectively. However, despite these small changes, significant changes in the structures are observed for some systems, such as proton transfer and hydrogen bonding rearrangements. The paper represents the first step in the process of creating a benchmark set of barriers computed for systems that are relatively large and representative of enzymatic reactions, a considerable challenge for any one research group but possible through a concerted effort by the community. We end by outlining steps needed to expand and

  18. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2011-12-31

    This project (10/01/2010-9/30/2013), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This proposal will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. We will develop novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; we will perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; we will perform material characterizations and oxidation/corrosion tests; and we will demonstrate our new Thermal barrier coating (TBC) systems experimentally under Integrated gasification combined cycle (IGCC) environments. The durability of the coating will be examined using the proposed High Temperature/High Pressure Durability Test Rig under real syngas product compositions.

  19. Evolution of an intermittent lagoon-barrier system with rising sea level: observations and projections from the Muni-Pomadze lagoon, Ghana

    Science.gov (United States)

    Davies-Vollum, Sian

    2016-04-01

    Intermittently closed lagoon-barrier systems are a transitory environment between land and sea that are influenced by fluvial and marine processes as well as human activities. Fluvial processes dominate most of the time, when the barrier is closed. However, when the barrier is breached an ephemeral connection between the lagoon and the ocean develops and estuarine-like conditions ensue. As sea level rises, the evolution of these systems from intermittently closed to open is dependent on multiple processes including barrier breaching, fragmentation and overwashing. Human intervention, often to prevent flooding, also has an impact. The Muni-Pomadze lagoon in central Ghana is a small, intermittently closed lagoon-barrier system that supports a local fishing community. A beach-barrier separates the lagoon from the ocean, impounding river water and sediment behind it for most of the year. At the end of a rainy season the barrier may be breached, either naturally or by human intervention to prevent flooding of dwellings on the barrier. Field observation, digital mapping and GIS analysis of the shoreline has enabled an understanding of how the barrier is evolving with rising sea level. The shore face of the barrier has shifted landwards with an average retreat rate of 0.22 m/yr. Small washover fans, developed at low points along the lagoon side of the barrier have developed. However, aerial photos reveal that these fans have remained stable since 1972 (earliest available air photos). The small size and stability of these fans suggests that overwashing is not an important factor in the evolution of the barrier and that the barrier is being eroded rather not moving landward. Erosion is particularly prevalent at the breach end of the barrier with an average rate of loss of 3 metres per year and palm trees that were providing stability to the barrier have been washed away. Unconsolidated sands forming a transient, spit-like feature have replaced the stable barrier, which

  20. Identifying the management barriers for establishing suggestions system: A case study of educational system

    Directory of Open Access Journals (Sweden)

    Masoud Nouri

    2012-10-01

    Full Text Available Suggestions system is one of the new cooperative management plans, which affects making good decisions, self-confidence and employees occupational approval. The aim of this research is to survey the barriers for establishment of suggestion system. The proposed study designs and distributes a questionnaire among 195 out of 26550 managers who work for educational system in city of Kermanshah, Iran. The primary purpose of this survey is to learn whether lack of accepting any risk on behalf of management team, conflict of interest in management style, lack of belief on suggestions system in an organization are important barriers of executing suggestions system in an organization or not. The results of Freedman test confirm all seven components of the hypothesis. As a result, lack of accepting risk among management team is number one barrier in having suggestion system followed by existing conflict between management style and suggestions system and lack of management's belief to suggestions system, weakness in education for suggestions system and fear in management disruption because of having suggestions system. The other barriers coming in the last priority in terms of their relative importance include lack of management's support to suggestions system and weakness in management position because of accepting suggestions system.

  1. Representing solute transport through the multi-barrier disposal system by simplified concepts

    Energy Technology Data Exchange (ETDEWEB)

    Poteri, A.; Nordman, H.; Pulkkanen, V-M. [VTT Technical Research Centre of Finland, Espoo (Finland); Kekaelaeinen, P. [Jyvaeskylae Univ. (Finland). Dept. pf Physics; Hautojaervi, A.

    2012-02-15

    The repository system chosen in Finland for spent nuclear fuel is composed of multiple successive transport barriers. If a waste canister is leaking, this multi-barrier system retards and limits the release rates of radionuclides into the biosphere. Analysis of radionuclide migration in the previous performance assessments has largely been based on numerical modelling of the repository system. The simplified analytical approach introduced here provides a tool to analyse the performance of the whole system using simplified representations of the individual transport barriers. This approach is based on the main characteristics of the individual barriers and on the generic nature of the coupling between successive barriers. In the case of underground repository the mass transfer between successive transport barriers is strongly restricted by the interfaces between barriers leading to well-mixed conditions in these barriers. The approach here simplifies the barrier system so that it can be described with a very simple compartment model, where each barrier is represented by a single, or in the case of buffer, by not more than two compartments. This system of compartments could be solved in analogy with a radioactive decay chain. The model of well mixed compartments lends itself to a very descriptive way to represent and analyse the barrier system because the relative efficiency of the different barriers in hindering transport of solutes can be parameterised by the solutes half-times in the corresponding compartments. In a real repository system there will also be a delay between the start of the inflow and the start of the outflow from the barrier. This delay can be important for the release rates of the short lived and sorbing radionuclides, and it was also included in the simplified representation of the barrier system. In a geological multi-barrier system, spreading of the outflowing release pulse is often governed by the typical behaviour of one transport barrier

  2. Curvature behaviour of multilayer specimens of thermal barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Blandin, G.; Bruenings, S.E.; Steinbrech, R.W.; Singheiser, L. [Forschungszentrum Juelich GmbH (Germany). Inst. fuer Werkstoffe und Verfahren der Energietechnik

    2000-07-01

    The impact of residual stresses on the elastic and plastic deformation behavior of plasma sprayed and physical vapor deposited thermal barrier systems was studied. In particular, multilayer specimen strips composed of plasma sprayed partially stabilized zirconia, oxidation resistant NiCoCrAlY bond-coat and Ni-based superalloy substrate were tested. The experiments focused on the in-situ observation of specimen curvature during thermal cycling between room temperature and 1000 C. The mechanical response of specimens with different layer thickness was analyzed with a thermoelastic model to derive elastic modulus and thermal expansion of the ceramic top coat, both parameters as a function of temperature. With the thermoelastic data of all three layers, the residual stress distribution could be calculated analytically. The results of the two coating variants are compared. The deviation from thermoelastic behavior at higher temperature is discussed in terms of stress relaxation in the bond coat due to plastic deformation. (orig.)

  3. PEBS. Long-term performance of engineered barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Wieczorek, Klaus; Czaikowski, Oliver; Miehe, Ruediger

    2014-12-15

    The evolution of the engineered barrier system (EBS) of geological repositories for radioactive waste has been the subject of many national and international research programmes. The emphasis of the research activities was on the elaboration of a detailed understanding of the complex THMC processes, which are expected to evolve in the early post closure period in the near field. From the perspective of radiological long-term safety, an in-depth understanding of these coupled processes is of great significance, because the evolution of the EBS during the early post-closure phase may have a non-negligible impact on the radiological safety functions at the time when the canisters breach. Unexpected process interactions during the resaturation phase could impair the safety-relevant parameters in the EBS (e. g. swelling pressure, hydraulic conductivity, diffusivity).

  4. Improving the safety features of general practice computer systems

    OpenAIRE

    Anthony Avery; Boki Savelyich; Sheila Teasdale

    2003-01-01

    General practice computer systems already have a number of important safety features. However, there are problems in that general practitioners (GPs) have come to rely on hazard alerts when they are not foolproof. Furthermore, GPs do not know how to make best use of safety features on their systems. There are a number of solutions that could help to improve the safety features of general practice computer systems and also help to improve the abilities of healthcare professionals to use these ...

  5. Novel spectral features of nanoelectromechanical systems

    KAUST Repository

    Tahir, M.

    2014-02-17

    Electron transport through a quantum dot or single molecule coupled to a quantum oscillator is studied by the Keldysh nonequilibrium Green\\'s function formalism to obtain insight into the quantum dynamics of the electronic and oscillator degrees of freedom. We tune the electronic level of the quantum dot by a gate voltage, where the leads are kept at zero temperature. Due to the nonequilibrium distribution of the electrons in the quantum dot, the spectral function becomes a function of the gate voltage. Novel spectral features are identified for the ground and excited states of nanomechanical oscillators that can be used to enhance the measurement sensitivity.

  6. Nanoscale drug delivery systems and the blood–brain barrier

    Directory of Open Access Journals (Sweden)

    Alyautdin R

    2014-02-01

    Full Text Available Renad Alyautdin,1 Igor Khalin,2 Mohd Ismail Nafeeza,1 Muhammad Huzaimi Haron,1 Dmitry Kuznetsov31Faculty of Medicine, Universiti Teknologi MARA (UiTM, Sungai Buloh, Selangor, Malaysia; 2Faculty of Medicine and Defence Health, National Defence University of Malaysia (NDUM, Kuala Lumpur, Malaysia; 3Department of Medicinal Nanobiotechnologies, N. I. Pirogoff Russian State Medical University, Moscow, RussiaAbstract: The protective properties of the blood–brain barrier (BBB are conferred by the intricate architecture of its endothelium coupled with multiple specific transport systems expressed on the surface of endothelial cells (ECs in the brain's vasculature. When the stringent control of the BBB is disrupted, such as following EC damage, substances that are safe for peripheral tissues but toxic to neurons have easier access to the central nervous system (CNS. As a consequence, CNS disorders, including degenerative diseases, can occur independently of an individual's age. Although the BBB is crucial in regulating the biochemical environment that is essential for maintaining neuronal integrity, it limits drug delivery to the CNS. This makes it difficult to deliver beneficial drugs across the BBB while preventing the passage of potential neurotoxins. Available options include transport of drugs across the ECs through traversing occludins and claudins in the tight junctions or by attaching drugs to one of the existing transport systems. Either way, access must specifically allow only the passage of a particular drug. In general, the BBB allows small molecules to enter the CNS; however, most drugs with the potential to treat neurological disorders other than infections have large structures. Several mechanisms, such as modifications of the built-in pumping-out system of drugs and utilization of nanocarriers and liposomes, are among the drug-delivery systems that have been tested; however, each has its limitations and constraints. This review

  7. Stochastic Resonance of Single (Independent of Each Other) Protein Motor System with Fluctuating Potential Barrier

    Institute of Scientific and Technical Information of China (English)

    MA Song-Hua; LI Jing-Hui; JIANG Yong-Qing; FANG Jian-Ping

    2008-01-01

    A single (independent of each other) protein motor system with fluctuating potential barrier and subject to sine electric field is investigated. We first derive the approximate Langevin equation of this system with fluctuating potential barrier. Then from this approximate Langevin equation, we calculate the signal-to-noise ratio (SNR) in the adiabatic limit. The phenomenon of stochastic resonance is found for this protein motor system with fluctuating potential barrier.

  8. Portable weighing system with alignment features

    Science.gov (United States)

    Abercrombie, Robert Knox; Richardson, Gregory David; Scudiere, Matthew Bligh; Sheldon, Frederick T.

    2012-11-06

    A system for weighing a load is disclosed. The weighing system includes a pad having at least one transducer for weighing a load disposed on the pad. In some embodiments the pad has a plurality of foot members and the weighing system may include a plate that disposed underneath the pad for receiving the plurality of foot member and for aligning the foot members when the weighing system is installed. The weighing system may include a spacer disposed adjacent the pad and in some embodiments, a spacer anchor operatively secures the spacer to a support surface, such as a plate, a railway bed, or a roadway. In some embodiments the spacer anchor operatively secures both the spacer and the pad to a roadway.

  9. Nanoscale drug delivery systems and the blood-brain barrier.

    Science.gov (United States)

    Alyautdin, Renad; Khalin, Igor; Nafeeza, Mohd Ismail; Haron, Muhammad Huzaimi; Kuznetsov, Dmitry

    2014-01-01

    The protective properties of the blood-brain barrier (BBB) are conferred by the intricate architecture of its endothelium coupled with multiple specific transport systems expressed on the surface of endothelial cells (ECs) in the brain's vasculature. When the stringent control of the BBB is disrupted, such as following EC damage, substances that are safe for peripheral tissues but toxic to neurons have easier access to the central nervous system (CNS). As a consequence, CNS disorders, including degenerative diseases, can occur independently of an individual's age. Although the BBB is crucial in regulating the biochemical environment that is essential for maintaining neuronal integrity, it limits drug delivery to the CNS. This makes it difficult to deliver beneficial drugs across the BBB while preventing the passage of potential neurotoxins. Available options include transport of drugs across the ECs through traversing occludins and claudins in the tight junctions or by attaching drugs to one of the existing transport systems. Either way, access must specifically allow only the passage of a particular drug. In general, the BBB allows small molecules to enter the CNS; however, most drugs with the potential to treat neurological disorders other than infections have large structures. Several mechanisms, such as modifications of the built-in pumping-out system of drugs and utilization of nanocarriers and liposomes, are among the drug-delivery systems that have been tested; however, each has its limitations and constraints. This review comprehensively discusses the functional morphology of the BBB and the challenges that must be overcome by drug-delivery systems and elaborates on the potential targets, mechanisms, and formulations to improve drug delivery to the CNS.

  10. Geographic Names Information System (GNIS) Cultural Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  11. Geographic Names Information System (GNIS) Landform Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  12. Geographic Names Information System (GNIS) Admin Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  13. Geographic Names Information System (GNIS) Community Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  14. Geographic Names Information System (GNIS) Antarctica Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  15. Geographic Names Information System (GNIS) Historical Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  16. Geographic Names Information System (GNIS) Transportation Features

    Data.gov (United States)

    Department of Homeland Security — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  17. GNIS: Geographic Names Information Systems - All features

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) actively seeks data from and partnerships with Government agencies at all levels and other interested organizations....

  18. High-resolution reconstruction of a coastal barrier system

    DEFF Research Database (Denmark)

    Fruergaard, Mikkel; Andersen, Thorbjørn Joest; Nielsen, Lars Henrik

    2015-01-01

    from retreat of the barrier island and probably also due to formation of a tidal inlet close to the study area. Continued transgression and shoreface retreat created a distinct hiatus and wave ravinement surface in the seaward part of the CBS before the barrier shoreline stabilised between 5.0 and 4.......5 ka ago. Back-barrier shoreline erosion due to sediment starvation in the back-barrier basin, was pronounced from 4.5 to 2.5 ka ago but the last 2.5 kyr barrier sedimentation has kept up with and outpaced sea-level. The last 0.4 kyr the CBS has been episodically prograding. Sediment accumulation shows...

  19. On Dynamic Systems with Piecewise Linear Feature

    Directory of Open Access Journals (Sweden)

    Amalia Ţîrdea

    2010-10-01

    Full Text Available Impact dynamics is considered to be one of the most important problems which arise in vibrating systems. Such impact oscillator occurs in the motion with amplitude constraining stop. In the past years, this simple model has been found rich phenomena and given benefit for understanding of impact systems. Different types of impacting response, such as periodic and non-periodic oscillations, can be predicted by using bifurcation diagrams. Many mechanical systems in engineering applications represent systems which are driven in some way and which undergo intermittent or a continuous sequence of contacts with limiting motion by constraints. For example, the principles of the operation of vibration hammers, impact dampers, inertial shakers, milling and forming machines etc, are based on the impact action for moving bodies. With other equipment, machines with clearances, heat exchangers, steam generator tubes, fuel rods in nuclear power plants, rolling railway wheel sets, piping systems, gear transmissions and so on, impacts also occur, but they are undesirable as they bring about failures, strains, and increased noise levels.

  20. An Overview of Android Operating System and Its Security Features

    Directory of Open Access Journals (Sweden)

    Rajinder Singh

    2014-02-01

    Full Text Available Android operating system is one of the most widely used operating system these days. Android Operating System is mainly divided into four main layers: the kernel, libraries, application framework and applications. Its kernel is based on Linux. Linux kernel is used to manage core system services such as virtual memory, networking, drivers, and power management. In these paper different features of architecture of Android OS as well security features of Android OS are discussed.

  1. Feature Detection Systems Enhance Satellite Imagery

    Science.gov (United States)

    2009-01-01

    -resolution satellites, which provide the benefit of images detailed enough to reveal large features like highways while still broad enough for global coverage, continue to scan the entirety of the Earth s surface. In 2012, NASA plans to launch the Landsat Data Continuity Mission (LDCM), or Landsat 8, to extend the Landsat program s contributions to cartography, water management, natural disaster relief planning, and more.

  2. Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution.

    Science.gov (United States)

    Capanni, Cristina; Squarzoni, Stefano; Cenni, Vittoria; D'Apice, Maria Rosaria; Gambineri, Alessandra; Novelli, Giuseppe; Wehnert, Manfred; Pasquali, Renato; Maraldi, Nadir M; Lattanzi, Giovanna

    2012-10-01

    Prelamin A processing impairment is a common feature of a restricted group of rare genetic alterations/disorders associated with a wide range of clinical phenotypes. Changes in histone posttranslational modifications, alterations in non-histone chromatin proteins and chromatin disorganization have been specifically linked to impairment of specific, distinct prelamin A processing steps, but the molecular mechanism involved in these processes is not yet understood . In this study, we show that the accumulation of wild-type prelamin A detected in restrictive dermopathy (RD), as well as the accumulation of mutated forms of prelamin A identified in familial partial lipodystrophy (FPLD) and mandibuloacral dysplasia (MADA), affect the nuclear localization of barrier-to-autointegration factor (BAF), a protein able to link lamin A precursor to chromatin remodeling functions. Our findings, in accordance with previously described results, support the hypothesis of a prelamin A involvement in BAF nuclear recruitment and suggest BAF-prelamin A complex as a protein platform usually activated in prelamin A-accumulating diseases. Finally, we demonstrate the involvement of the inner nuclear membrane protein emerin in the proper localization of BAF-prelamin A complex.

  3. Ranking System for Opinion Mining of Features from Review Documents

    Directory of Open Access Journals (Sweden)

    Tanvir Ahmad

    2012-07-01

    Full Text Available With the exponential growth of the web there has been explosive increase in the user generated contents in the form of customer reviews, blogs, discussion forums, social networks etc. Most of the contents are stored in the form of unstructured or semi structured data from where distillation of knowledge is a challenging task. In this paper we propose a feature wise opinion mining system which first extracts features from user generated contents, then determines the intensity of the opinions by giving emphasis to the modifier of the words, which expresses opinions. It finds the numeric score of all the features using Senti-WordNet and then calculates the overall orientation of the feature to determine how intense the opinion is for both the positive and negative features. The positive and negative features are identified by extracting the associated modifiers and opinions. The summary is presented by specifying the features in descending order of importance.

  4. MERCURY OXIDIZATION IN NON-THERMAL PLASMA BARRIER DISCHARGE SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    V.K. Mathur

    2003-02-01

    In the past decade, the emission of toxic elements from human activities has become a matter of great public concern. Hg, As, Se and Cd typically volatilize during a combustion process and are not easily caught with conventional air pollution control techniques. In addition, there is no pollution prevention technique available now or likely be available in the foreseeable future that can prevent the emission of these trace elements. These trace elements pose additional scientific challenge as they are present at only ppb levels in large gas streams. Mercury, in particular, has attracted significant attention due to its high volatility, toxicity and potential threat to human health. In the present research work, a non-thermal plasma dielectric barrier discharge technique has been used to oxidize Hg{sup 0}(g) to HgO. The basic premise of this approach is that Hg{sup 0} in vapor form cannot be easily removed in an absorption tower whereas HgO as a particulate is amiable to water scrubbing. The work presented in this report consists of three steps: (1) setting-up of an experimental apparatus to generate mercury vapors at a constant rate and modifying the existing non-thermal plasma reactor system, (2) solving the analytical challenge for measuring mercury vapor concentration at ppb level, and (3) conducting experiments on mercury oxidation under plasma conditions to establish proof of concept.

  5. Engineered Barrier Systems Thermal-Hydraulic-Chemical Column Test Report

    Energy Technology Data Exchange (ETDEWEB)

    W.E. Lowry

    2001-12-13

    The Engineered Barrier System (EBS) Thermal-Hydraulic-Chemical (THC) Column Tests provide data needed for model validation. The EBS Degradation, Flow, and Transport Process Modeling Report (PMR) will be based on supporting models for in-drift THC coupled processes, and the in-drift physical and chemical environment. These models describe the complex chemical interaction of EBS materials, including granular materials, with the thermal and hydrologic conditions that will be present in the repository emplacement drifts. Of particular interest are the coupled processes that result in mineral and salt dissolution/precipitation in the EBS environment. Test data are needed for thermal, hydrologic, and geochemical model validation and to support selection of introduced materials (CRWMS M&O 1999c). These column tests evaluated granular crushed tuff as potential invert ballast or backfill material, under accelerated thermal and hydrologic environments. The objectives of the THC column testing are to: (1) Characterize THC coupled processes that could affect performance of EBS components, particularly the magnitude of permeability reduction (increases or decreases), the nature of minerals produced, and chemical fractionation (i.e., concentrative separation of salts and minerals due to boiling-point elevation). (2) Generate data for validating THC predictive models that will support the EBS Degradation, Flow, and Transport PMR, Rev. 01.

  6. ARCTIC FOUNDATIONS, INC. FREEZE BARRIER SYSTEM - SITE TECHNOLOGY CAPSULE

    Science.gov (United States)

    Arctic Foundations, Inc. (AFI), of Anchorage, Alaska has developed a freeze barrier technology designed to prevent the migration of contaminants in groundwater by completely isolating contaminant source areas until appropriate remediation techniques can be applied. With this tec...

  7. A Subset Feature Elimination Mechanism for Intrusion Detection System

    Directory of Open Access Journals (Sweden)

    Herve Nkiama

    2016-04-01

    Full Text Available several studies have suggested that by selecting relevant features for intrusion detection system, it is possible to considerably improve the detection accuracy and performance of the detection engine. Nowadays with the emergence of new technologies such as Cloud Computing or Big Data, large amount of network traffic are generated and the intrusion detection system must dynamically collected and analyzed the data produce by the incoming traffic. However in a large dataset not all features contribute to represent the traffic, therefore reducing and selecting a number of adequate features may improve the speed and accuracy of the intrusion detection system. In this study, a feature selection mechanism has been proposed which aims to eliminate non-relevant features as well as identify the features which will contribute to improve the detection rate, based on the score each features have established during the selection process. To achieve that objective, a recursive feature elimination process was employed and associated with a decision tree based classifier and later on, the suitable relevant features were identified. This approach was applied on the NSL-KDD dataset which is an improved version of the previous KDD 1999 Dataset, scikit-learn that is a machine learning library written in python was used in this paper. Using this approach, relevant features were identified inside the dataset and the accuracy rate was improved. These results lend to support the idea that features selection improve significantly the classifier performance. Understanding the factors that help identify relevant features will allow the design of a better intrusion detection system.

  8. Design of noise barrier inspection system for high-speed railway

    Science.gov (United States)

    Liu, Bingqian; Shao, Shuangyun; Feng, Qibo; Ma, Le; Cholryong, Kim

    2016-10-01

    The damage of noise barriers will highly reduce the transportation safety of the high-speed railway. In this paper, an online inspection system of noise barrier based on laser vision for the safety of high-speed railway is proposed. The inspection system, mainly consisted of a fast camera and a line laser, installed in the first carriage of the high-speed CIT(Composited Inspection Train).A Laser line was projected on the surface of the noise barriers and the images of the light line were received by the camera while the train is running at high speed. The distance between the inspection system and the noise barrier can be obtained based on laser triangulation principle. The results of field tests show that the proposed system can meet the need of high speed and high accuracy to get the contour distortion of the noise barriers.

  9. System Entropy and Its Application in Feature Selection

    Institute of Scientific and Technical Information of China (English)

    ZHAO Jun; WU Zhong-fu; LI Hua

    2004-01-01

    Feature selection is always an important issue in the research on data mining technologies. However, the problem of optimal feature selection is NP hard. Therefore, heuristic approaches are more practical to actual learning systems. Usually, that kind of algorithm selects features with the help of a heuristic metric compactum to measure the relative importance of features in a learning system. Here a new notion of 'system entropy' is described in terms of rough set theory, and then some of its algebraic characteristics are studied. After its intrinsic value biase is effectively counteracted, the system entropy is applied in BSE, a new heuristic algorithm for feature selection. BSE is efficient, whose time complexity is lower than that of analogous algorithms; BSE is also effective, which can produce the optimal results in the mini-feature biased sense from varieties of learning systems. Besides, BSE is tolerant and also flexible to the inconsistency of a learning system, consequently able to elegantly handle data noise in the learning system.

  10. A Subset Feature Elimination Mechanism for Intrusion Detection System

    OpenAIRE

    Herve Nkiama; Syed Zainudeen Mohd Said; Muhammad Saidu

    2016-01-01

    several studies have suggested that by selecting relevant features for intrusion detection system, it is possible to considerably improve the detection accuracy and performance of the detection engine. Nowadays with the emergence of new technologies such as Cloud Computing or Big Data, large amount of network traffic are generated and the intrusion detection system must dynamically collected and analyzed the data produce by the incoming traffic. However in a large dataset not all features con...

  11. Iris Recognition System Based on Feature Level Fusion

    Directory of Open Access Journals (Sweden)

    Dr. S. R. Ganorkar

    2013-11-01

    Full Text Available Multibiometric systems utilize the evidence presented by multiple biometric sources (e.g., face and fingerprint, multiple fingers of a single user, multiple matchers, etc. in order to determine or verify the identity of an individual. Information from multiple sources can be consolidated in several distinct levels. But fusion of two different biometric traits are difficult due to (i the feature sets of multiple modalities may be incompatible (e.g., minutiae set of fingerprints and eigen-coefficients of face; (ii the relationship between the feature spaces of different biometric systems may not be known; (iii concatenating two feature vectors may result in a feature vector with very large dimensionality leading to the `curse of dimensionality problem, huge storage space and different processing algorithm. Also if we are use multiple images of single biometric trait, then it doesn’t show much variations. So in this paper, we present a efficient technique of feature-based fusion in a multimodal system where left eye and right eye are used as input. Iris recognition basically contains iris location, feature extraction, and identification. This algorithm uses canny edge detection to identify inner and outer boundary of iris. Then this image is feed to Gabor wavelet transform to extract the feature and finally matching is done by using indexing algorithm. The results from the analysis of works indicate that the proposed technique can lead to substantial improvement in performance.

  12. A harmonic linear dynamical system for prominent ECG feature extraction.

    Science.gov (United States)

    Thi, Ngoc Anh Nguyen; Yang, Hyung-Jeong; Kim, SunHee; Do, Luu Ngoc

    2014-01-01

    Unsupervised mining of electrocardiography (ECG) time series is a crucial task in biomedical applications. To have efficiency of the clustering results, the prominent features extracted from preprocessing analysis on multiple ECG time series need to be investigated. In this paper, a Harmonic Linear Dynamical System is applied to discover vital prominent features via mining the evolving hidden dynamics and correlations in ECG time series. The discovery of the comprehensible and interpretable features of the proposed feature extraction methodology effectively represents the accuracy and the reliability of clustering results. Particularly, the empirical evaluation results of the proposed method demonstrate the improved performance of clustering compared to the previous main stream feature extraction approaches for ECG time series clustering tasks. Furthermore, the experimental results on real-world datasets show scalability with linear computation time to the duration of the time series.

  13. A Harmonic Linear Dynamical System for Prominent ECG Feature Extraction

    Directory of Open Access Journals (Sweden)

    Ngoc Anh Nguyen Thi

    2014-01-01

    Full Text Available Unsupervised mining of electrocardiography (ECG time series is a crucial task in biomedical applications. To have efficiency of the clustering results, the prominent features extracted from preprocessing analysis on multiple ECG time series need to be investigated. In this paper, a Harmonic Linear Dynamical System is applied to discover vital prominent features via mining the evolving hidden dynamics and correlations in ECG time series. The discovery of the comprehensible and interpretable features of the proposed feature extraction methodology effectively represents the accuracy and the reliability of clustering results. Particularly, the empirical evaluation results of the proposed method demonstrate the improved performance of clustering compared to the previous main stream feature extraction approaches for ECG time series clustering tasks. Furthermore, the experimental results on real-world datasets show scalability with linear computation time to the duration of the time series.

  14. Digital signature systems based on smart card and fingerprint feature

    Institute of Scientific and Technical Information of China (English)

    You Lin; Xu Maozhi; Zheng Zhiming

    2007-01-01

    Two signature systems based on smart cards and fingerprint features are proposed. In one signature system, the cryptographic key is stored in the smart card and is only accessible when the signer's extracted fingerprint features match his stored template. To resist being tampered on public channel, the user's message and the signed message are encrypted by the signer's public key and the user's public key, respectively. In the other signature system, the keys are generated by combining the signer's fingerprint features, check bits, and a rememberable key,and there are no matching process and keys stored on the smart card. Additionally, there is generally more than one public key in this system, that is, there exist some pseudo public keys except a real one.

  15. Organisational Semiosis: integration and serparation between system features and workpractices

    Directory of Open Access Journals (Sweden)

    Rodney Clarke

    2001-05-01

    Full Text Available Traditional information systems theory and practice assumes a tight coupling or integration between workpractices in organisations and the information systems which are notionally built to support them. The relationship between the integration and the separation of workpractices and system features has been theorised as dialectical. It has also been argued that the goal of system design would be to achieve a dynamic equilibrium within this dialectic. However, this paper argues that the above mentioned dialectic forged between integrationist and separations! views can be usefully critiqued by applying systemic semiotics. Systemic semiotics refers to a combination of systemic functional linguistics (a semiotic model of language and its extensions into a general semiotic framework called social semiotics. The latter draws heavily on the notion of dialogism which this paper proposes is useful in rethinking the relationship between workpractices and information systems. In addition, concepts of text and context are drawn from systemic functional linguistics in analysing the workpractices associated with the use of actual information systems features. Two examples are used to explicate this dialogic relationship, including: (i the dynamic renegotiation of a workpractice which is assumed to be closely integrated to a system feature (negotiated separation, and (ii the extension of the system into other locations by means of communicatively organising materials and users in the workplace (indirect integration.

  16. Unavailability analysis of digital engineered safety feature actuation system

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hyun Gook; Jang, Seung Cheol [KAERI, Taejon (Korea, Republic of); Wiharjo, Sudarno [National Nuclear Agency-BATAN, Tangerang (Indonesia)

    2003-07-01

    This paper quantitatively presents the results of the fault tree analysis of Digital Engineered Safety Feature Actuation System which is one of the most important signal generation systems in nuclear power plant because it generates the signal for mitigating possible accidents. In this paper, as an example, we explore the case of auxiliary feedwater actuation signal. Based on the analysis results, we quantitatively explain the relationship between the important characteristics of digital systems and the system unavailability. Similarly to the PSA result of Digital Plant Protection System, we find out some factors remarkably affect the system unavailability. They are the common cause failures and the coverage of fault tolerant mechanisms. Human operator's backup also plays very important role. In this analysis we ignore the effect of software failure. We also compare the result with the PSA result of conventional analog Engineered Safety Feature Actuation System.

  17. Disposal systems evaluations and tool development : Engineered Barrier System (EBS) evaluation.

    Energy Technology Data Exchange (ETDEWEB)

    Rutqvist, Jonny (LBNL); Liu, Hui-Hai (LBNL); Steefel, Carl I. (LBNL); Serrano de Caro, M. A. (LLNL); Caporuscio, Florie Andre (LANL); Birkholzer, Jens T. (LBNL); Blink, James A. (LLNL); Sutton, Mark A. (LLNL); Xu, Hongwu (LANL); Buscheck, Thomas A. (LLNL); Levy, Schon S. (LANL); Tsang, Chin-Fu (LBNL); Sonnenthal, Eric (LBNL); Halsey, William G. (LLNL); Jove-Colon, Carlos F.; Wolery, Thomas J. (LLNL)

    2011-01-01

    Key components of the nuclear fuel cycle are short-term storage and long-term disposal of nuclear waste. The latter encompasses the immobilization of used nuclear fuel (UNF) and radioactive waste streams generated by various phases of the nuclear fuel cycle, and the safe and permanent disposition of these waste forms in geological repository environments. The engineered barrier system (EBS) plays a very important role in the long-term isolation of nuclear waste in geological repository environments. EBS concepts and their interactions with the natural barrier are inherently important to the long-term performance assessment of the safety case where nuclear waste disposition needs to be evaluated for time periods of up to one million years. Making the safety case needed in the decision-making process for the recommendation and the eventual embracement of a disposal system concept requires a multi-faceted integration of knowledge and evidence-gathering to demonstrate the required confidence level in a deep geological disposal site and to evaluate long-term repository performance. The focus of this report is the following: (1) Evaluation of EBS in long-term disposal systems in deep geologic environments with emphasis on the multi-barrier concept; (2) Evaluation of key parameters in the characterization of EBS performance; (3) Identification of key knowledge gaps and uncertainties; and (4) Evaluation of tools and modeling approaches for EBS processes and performance. The above topics will be evaluated through the analysis of the following: (1) Overview of EBS concepts for various NW disposal systems; (2) Natural and man-made analogs, room chemistry, hydrochemistry of deep subsurface environments, and EBS material stability in near-field environments; (3) Reactive Transport and Coupled Thermal-Hydrological-Mechanical-Chemical (THMC) processes in EBS; and (4) Thermal analysis toolkit, metallic barrier degradation mode survey, and development of a Disposal Systems

  18. Functions of an engineered barrier system for a nuclear waste repository in basalt

    Energy Technology Data Exchange (ETDEWEB)

    Coons, W.E.; Moore, E.L.; Smith, M.J.; Kaser, J.D.

    1980-01-01

    Defined in this document are the functions of components selected for an engineered barrier system for a nuclear waste repository in basalt. The definitions provide a focal point for barrier material research and development by delineating the purpose and operative lifetime of each component of the engineered system. A five-component system (comprised of waste form, canister, buffer, overpack, and tailored backfill) is discussed in terms of effective operation throughout the course of repository history, recognizing that the emplacement environment changes with time. While components of the system are mutually supporting, redundancy is provided by subsystems of physical and chemical barriers which act in concert with the geology to provide a formidable barrier to transport of hazardous materials to the biosphere. The operating philosophy of the conceptual engineered barrier system is clarified by examples pertinent to storage in basalt, and a technical approach to barrier design and material selection is proposed. A method for system validation and qualification is also included which considers performance criteria proposed by external agencies in conjunction with site-specific models and risk assessment to define acceptable levels of system performance.

  19. Imaging systems and applications: introduction to the feature.

    Science.gov (United States)

    Imai, Francisco H; Linne von Berg, Dale C; Skauli, Torbjørn; Tominaga, Shoji; Zalevsky, Zeev

    2014-05-01

    Imaging systems have numerous applications in industrial, military, consumer, and medical settings. Assembling a complete imaging system requires the integration of optics, sensing, image processing, and display rendering. This issue features original research ranging from design of stimuli for human perception, optics applications, and image enhancement to novel imaging modalities in both color and infrared spectral imaging, gigapixel imaging as well as a systems perspective to imaging.

  20. Electronic image stabilization system based on global feature tracking

    Institute of Scientific and Technical Information of China (English)

    Zhu Juanjuan; Guo Baolong

    2008-01-01

    A new robust electronic image stabilization system is presented, which involves feature-point, tracking based global motion estimation and Kalman filtering based motion compensation. First, global motion is estimated from the local motions of selected feature points. Considering the local moving objects or the inevitable mismatch,the matching validation, based on the stable relative distance between the points set is proposed, thus maintaining high accuracy and robustness. Next, the global motion parameters are accumulated for correction by Kalman filter-ation. The experimental result illustrates that the proposed system is effective to stabilize translational, rotational,and zooming jitter and robust to local motions.

  1. Barrier function in the peripheral and central nervous system-a review.

    Science.gov (United States)

    Reinhold, A K; Rittner, H L

    2017-01-01

    The peripheral (PNS) and central nervous system (CNS) are delicate structures, highly sensitive to homeostatic changes-and crucial for basic vital functions. Thus, a selection of barriers ensures the protection of the nervous system from noxious blood-borne or surrounding stimuli. In this chapter, anatomy and functioning of the blood-nerve (BNB), the blood-brain (BBB), and the blood-spinal cord barriers (BSCB) are presented and the key tight junction (TJ) proteins described: claudin-1, claudin-3, claudin-5, claudin-11, claudin-12, claudin-19, occludin, Zona occludens-1 (ZO-1), and tricellulin are by now identified as relevant for nerval barriers. Different diseases can lead to or be accompanied by neural barrier disruption, and impairment of these barriers worsens pathology. Peripheral nerve injury and inflammatory polyneuropathy cause an increased permeability of BNB as well as BSCB, while, e.g., diseases of the CNS such as amyotrophic lateral sclerosis, multiple sclerosis, spinal cord injury, or Alzheimer's disease can progress and worsen through barrier dysfunction. Moreover, the complex role and regulation of the BBB after ischemic stroke is described. On the other side, PNS and CNS barriers hamper the delivery of drugs in diseases when the barrier is intact, e.g., in certain neurodegenerative diseases or inflammatory pain. Understanding of the barrier - regulating processes has already lead to the discovery of new molecules as drug enhancers. In summary, the knowledge of all of these mechanisms might ultimately lead to the invention of drugs to control barrier function to help ameliorating or curing neurological diseases.

  2. CHARACTERIZATION OF BENTONITE FOR ENGINEERED BARRIER SYSTEMS IN RADIOACTIVE WASTE DISPOSAL SITES

    Directory of Open Access Journals (Sweden)

    Dubravko Domitrović

    2012-07-01

    Full Text Available Engineered barrier systems are used in radioactive waste disposal sites in order to provide better protection of humans and the environment from the potential hazards associated with the radioactive waste disposal. The engineered barrier systems usually contain cement or clay (bentonite because of their isolation properties and long term performance. Quality control tests of clays are the same for all engineering barrier systems. Differences may arise in the required criteria to be met due for different application. Prescribed clay properties depend also on the type of host rocks. This article presents radioactive waste management based on best international practice. Standard quality control procedures for bentonite used as a sealing barrier in radioactive waste disposal sites are described as some personal experiences and results of the index tests (free swelling index, water adsorption capacity, plasticity limits and hydraulic permeability of bentonite (the paper is published in Croatian.

  3. Time Frequency Features of Rotor Systems with Slowly Varying Mass

    Directory of Open Access Journals (Sweden)

    Tao Yu

    2011-01-01

    Full Text Available With the analytic method and numerical method respectively, the asymptotic solutions and finite element model of rotor system with single slowly varying mass is obtained to investigate the time frequency features of such rotor system; furthermore, with given model of slowly varying mass, the rotor system with dual slowly varying mass is studied. For the first order approximate solution is used, there exists difference between the results with analytic method and numerical method. On the base of common characteristics of rotor system with dual slowly varying mass, the general rules and formula describing the frequency distribution of rotor system with multiple slowly varying mass are proposed.

  4. Reactive barrier system for nitrate removal from mine effluents in northern Sweden: Laboratory experiments

    Science.gov (United States)

    Herbert, Roger

    2010-05-01

    Laboratory column experiments have been conducted to determine nitrate removal rates from mine effluents by denitrification, with the purpose of providing initial data for the construction of a pilot scale reactive barrier system at the Malmberget iron mine, Sweden. Experiments were conducted at several different flow rates at 5C, 10C and room temperature; annual mean temperatures at the Malmberget site lie close to 0C. Columns were filled with an organic substrate consisting of sawdust mixed with sewage sludge, the source of denitrifying bacteria, supported by oven-dried clay pellets. Apparent denitrification rates, calculated from inflow and outflow nitrate concentrations and column hydraulic residence time, ranged from 5 to 13 mg N/L/d, with the lowest rates corresponding to the 5C experiments. These rates are, however, limited to a certain degree by the low flow rate and the supply of electrons acceptors (i.e. nitrate) to denitrifying bacteria. Results from the column experiment have been used to construct a barrier system in Malmberget, Sweden. Trial runs with the pilot-scale barrier will be conducted during 2010, with the purpose of determining the performance of the barrier as mean air temperatures increase from below to above 0C and saturated flow commences in the barrier. The barrier system is constructed as a rectangular container with steel sheet walls (9m length in flow direction, 1.5m deep), and the flow rate will be adjusted to a hydraulic residence time of 1 day. The pilot-scale barrier system currently lies above ground, but a permanent barrier system would be installed below the ground surface so that the system can be maintained at positive temperatures throughout the year.

  5. Nonparametric statistical structuring of knowledge systems using binary feature matches

    DEFF Research Database (Denmark)

    Mørup, Morten; Glückstad, Fumiko Kano; Herlau, Tue

    2014-01-01

    Structuring knowledge systems with binary features is often based on imposing a similarity measure and clustering objects according to this similarity. Unfortunately, such analyses can be heavily influenced by the choice of similarity measure. Furthermore, it is unclear at which level clusters ha...

  6. Regulation of Copper Transport Crossing Brain Barrier Systems by Cu-ATPases: Effect of Manganese Exposure

    OpenAIRE

    Fu, Xue; Zhang, Yanshu; Jiang, Wendy; Monnot, Andrew Donald; Bates, Christopher Alexander; Zheng, Wei

    2014-01-01

    Regulation of cellular copper (Cu) homeostasis involves Cu-transporting ATPases (Cu-ATPases), i.e., ATP7A and ATP7B. The question as to how these Cu-ATPases in brain barrier systems transport Cu, i.e., toward brain parenchyma, cerebrospinal fluid (CSF), or blood, remained unanswered. This study was designed to characterize roles of Cu-ATPases in regulating Cu transport at the blood-brain barrier (BBB) and blood-CSF barrier (BCB) and to investigate how exposure to toxic manganese (Mn) altered ...

  7. Advances in the Dynallax solid-state dynamic parallax barrier autostereoscopic visualization display system.

    Energy Technology Data Exchange (ETDEWEB)

    Peterka, T.; Kooima, R. L.; Sandin, D. J.; Johnson, A.; Leigh, J.; DeFanti, T. A.; Mathematics and Computer Science; Univ. of Illinois at Chicago; Univ. of Calif. at San Diego

    2008-05-01

    A solid-state dynamic parallax barrier autostereoscopic display mitigates some of the restrictions present in static barrier systems such as fixed view-distance range, slow response to head movements, and fixed stereo operating mode. By dynamically varying barrier parameters in real time, viewers may move closer to the display and move faster laterally than with a static barrier system, and the display can switch between 3D and 2D modes by disabling the barrier on a per-pixel basis. Moreover, Dynallax can output four independent eye channels when two viewers are present, and both head-tracked viewers receive an independent pair of left-eye and right-eye perspective views based on their position in 3D space. The display device is constructed by using a dual-stacked LCD monitor where a dynamic barrier is rendered on the front display and a modulated virtual environment composed of two or four channels is rendered on the rear display. Dynallax was recently demonstrated in a small-scale head-tracked prototype system. This paper summarizes the concepts presented earlier, extends the discussion of various topics, and presents recent improvements to the system.

  8. Advances in the Dynallax solid-state dynamic parallax barrier autostereoscopic visualization display system.

    Science.gov (United States)

    Peterka, Tom; Kooima, Robert L; Sandin, Daniel J; Johnson, Andrew; Leigh, Jason; DeFanti, Thomas A

    2008-01-01

    A solid-state dynamic parallax barrier autostereoscopic display mitigates some of the restrictions present in static barrier systems, such as fixed view-distance range, slow response to head movements, and fixed stereo operating mode. By dynamically varying barrier parameters in real time, viewers may move closer to the display and move faster laterally than with a static barrier system, and the display can switch between 3D and 2D modes by disabling the barrier on a per-pixel basis. Moreover, Dynallax can output four independent eye channels when two viewers are present, and both head-tracked viewers receive an independent pair of left-eye and right-eye perspective views based on their position in 3D space. The display device is constructed by using a dual-stacked LCD monitor where a dynamic barrier is rendered on the front display and a modulated virtual environment composed of two or four channels is rendered on the rear display. Dynallax was recently demonstrated in a small-scale head-tracked prototype system. This paper summarizes the concepts presented earlier, extends the discussion of various topics, and presents recent improvements to the system.

  9. Ensemble Feature Extraction Modules for Improved Hindi Speech Recognition System

    Directory of Open Access Journals (Sweden)

    Malay Kumar

    2012-05-01

    Full Text Available Speech is the most natural way of communication between human beings. The field of speech recognition generates intrigues of man - machine conversation and due to its versatile applications; automatic speech recognition systems have been designed. In this paper we are presenting a novel approach for Hindi speech recognition by ensemble feature extraction modules of ASR systems and their outputs have been combined using voting technique ROVER. Experimental results have been shown that proposed system will produce better result than traditional ASR systems.

  10. Gas permeability of bentonite barriers: development, construction and testing of a measurement system

    Directory of Open Access Journals (Sweden)

    Heraldo Nunes Pitanga

    Full Text Available Abstract This article proposes a testing device to quickly and reliably estimate the gas permeability of bentonite-based clay barriers used in landfill cover systems. The testing methodology is based on a transient gas flow regime that passes through the barrier, therefore not requiring the use of sophisticated equipment that aim to maintain constant differential pressure and measure the gas flow, common requirements for testing methods under a permanent flow regime. To confirm the feasibility of the proposed technique, tests were performed on a pure hydrated bentonite layer, which subsequently encompassed samples of geosynthetic clay liner (GCL at different moisture contents. Geosynthetic clay liners are often selected as a part of the barrier layer for cover systems in solid waste landfills to prevent infiltration of rainfall and migration of biogas into the atmosphere. The results confirmed the equipment reliability and differentiate the different responses of the gas flow barriers studied, considering their different compositions and different moistures.

  11. Observability analysis of feature aided terminal guidance systems

    Institute of Scientific and Technical Information of China (English)

    Shijie Fan; Hongqi Fan; Huaitie Xiao; Jianpeng Fan; Qiang Fu

    2015-01-01

    Feature aided design of estimators and guidance laws can significantly improve the interception performance of the ter-minal guidance system. The achieved enhancement can be ef-fectively assessed by observability analysis methods. This paper first analyzes and discusses the existing assessment methods in a typical endgame scenario with target orientation observations. To get over their deficiencies, a novel singular value decomposition (SVD) method is proposed. Employing both theoretical analysis and numerical simulation, the proposed method can represent the degree of state observability which is enhanced by integrating tar-get features more completely and quantitatively.

  12. Investigation of endothelial growth using a sensors-integrated microfluidic system to simulate physiological barriers

    Directory of Open Access Journals (Sweden)

    Rajabi Taleieh

    2015-09-01

    Full Text Available In this paper we present a microfluidic system based on transparent biocompatible polymers with a porous membrane as substrate for various cell types which allows the simulation of various physiological barriers under continuous laminar flow conditions at distinct tunable shear rates. Besides live cell and fluorescence microscopy, integrated electrodes enable the investigation of the permeability and barrier function of the cell layer as well as their interaction with external manipulations using the Electric Cell-substrate Impedance Sensing (ECIS method.

  13. Perceptions of physicians about knowledge sharing barriers in Turkish health care system.

    Science.gov (United States)

    Gider, Ömer; Ocak, Saffet; Top, Mehmet

    2015-05-01

    This study was based on knowledge sharing barriers about attitudes of physicians in Turkish health care system. The present study aims to determine whether the knowledge sharing barriers about attitudes of physicians vary depending on gender, position, departments at hospitals, and hospital ownership status. This study was planned and conducted on physicians at one public hospital, one university hospital, and one private hospital in Turkey. 209 physicians were reached for data collection. The study was conducted in June-September 2014. The questionnaire (developed by A. Riege, (J. Knowl. Manag. 9(3):18-35, 2005)), five point Likert-type scale including 39 items having the potential of the physicians' knowledge- sharing attitudes and behaviors, was used in the study for data collection. Descriptive statistics, reliability analysis, student t test and ANOVA were used for data analysis. According to results of this study, there was medium level of knowledge sharing barriers within hospitals. In general, physicians had perceptions about the lowest level individual barriers, intermediate level organizational barriers and the highest level technological barriers perceptions, respectively. This study revealed that some knowledge sharing barriers about attitudes of physicians were significantly difference according to hospital ownership status, gender, position and departments. Most evidence medical decisions and evidence based practice depend on experience and knowledge of existing options and knowledge sharing in health care organizations. Physicians are knowledge and information-intensive and principal professional group in health care context.

  14. Complex Features in Lotka-Volterra Systems with Behavioral Adaptation

    Science.gov (United States)

    Tebaldi, Claudio; Lacitignola, Deborah

    Lotka-Volterra systems have played a fundamental role for mathematical modelling in many branches of theoretical biology and proved to describe, at least qualitatively, the essential features of many phenomena, see for example Murray [Murray 2002]. Furthermore models of that kind have been considered successfully also in quite different and less mathematically formalized context: Goodwin' s model of economic growth cycles [Goodwin 1967] and urban dynamics [Dendrinos 1992] are only two of a number of examples. Such systems can certainly be defined as complex ones and in fact the aim of modelling was essentially to clarify mechanims rather than to provide actual precise simulations and predictions. With regards to complex systems, we recall that one of their main feature, no matter of the specific definition one has in mind, is adaptation, i. e. the ability to adjust.

  15. Noncontacting Laser Inspection System for Dimensional Profiling of Space Application Thermal Barriers

    Science.gov (United States)

    Taylor, Shawn C.

    2011-01-01

    A noncontacting, two-dimensional (2-D) laser inspection system has been designed and implemented to dimensionally profile thermal barriers being developed for space vehicle applications. In a vehicle as-installed state, thermal barriers are commonly compressed between load sensitive thermal protection system (TPS) panels to prevent hot gas ingestion through the panel interface during flight. Loads required to compress the thermal barriers are functions of their construction, as well as their dimensional characteristics relative to the gaps in which they are installed. Excessive loads during a mission could damage surrounding TPS panels and have catastrophic consequences. As such, accurate dimensional profiling of thermal barriers prior to use is important. Due to the compliant nature of the thermal barriers, traditional contact measurement techniques (e.g., calipers and micrometers) are subjective and introduce significant error and variability into collected dimensional data. Implementation of a laser inspection system significantly enhanced the method by which thermal barriers are dimensionally profiled, and improved the accuracy and repeatability of collected data. A statistical design of experiments study comparing laser inspection and manual caliper measurement techniques verified these findings.

  16. Systemic connective tissue features in women with fibromuscular dysplasia.

    Science.gov (United States)

    O'Connor, Sarah; Kim, Esther Sh; Brinza, Ellen; Moran, Rocio; Fendrikova-Mahlay, Natalia; Wolski, Kathy; Gornik, Heather L

    2015-10-01

    Fibromuscular dysplasia (FMD) is a non-atherosclerotic disease associated with hypertension, headache, dissection, stroke, and aneurysm. The etiology is unknown but hypothesized to involve genetic and environmental components. Previous studies suggest a possible overlap of FMD with other connective tissue diseases that present with dissections and aneurysms. The aim of this study was to investigate the prevalence of connective tissue physical features in FMD. A total of 142 FMD patients were consecutively enrolled at a single referral center (97.9% female, 92.1% of whom had multifocal FMD). Data are reported for 139 female patients. Moderately severe myopia (29.1%), high palate (33.1%), dental crowding (29.7%), and early-onset arthritis (15.6%) were prevalent features. Classic connective features such as hypertelorism, cleft palate, and hypermobility were uncommon. The frequency of systemic connective tissue features was compared between FMD patients with a high vascular risk profile (having had ⩾1 dissection and/or ⩾2 aneurysms) and those with a standard vascular risk profile. A history of spontaneous pneumothorax (5.9% high risk vs 0% standard risk) and atrophic scarring (17.6% high risk vs 6.8% standard risk) were significantly more prevalent in the high risk group, pconnective tissue features such as high palate and pneumothorax were more prominent among FMD patients with a high vascular risk profile.

  17. Comparison of Windows and Linux Operating Systems in Advanced Features

    Directory of Open Access Journals (Sweden)

    P. Abhilash

    2015-02-01

    Full Text Available Comparison between the Microsoft Windows and Linux computer operating systems is a long-running discussion topic within the personal computer industry .This technical paper is mainly going to focus on the differences between windows and linux in all fields. Both Windows and Linux Operating systems have their own advantages and differ in functionalities and user friendliness. Linux and Microsoft Windows differ in philosophy, cost, versatility and stability, with each seeking to improve in their perceived weaker areas. This paper is mainly going to focus on the advanced features that are uniquely present in one operating system and not in other one.

  18. Effect of vadose zone on the steady-state leakage rates from landfill barrier systems.

    Science.gov (United States)

    Celik, B; Rowe, R K; Unlü, K

    2009-01-01

    Leakage rates are evaluated for a landfill barrier system having a compacted clay liner (CCL) underlain by a vadose zone of variable thickness. A numerical unsaturated flow model SEEP/W is used to simulate the moisture flow regime and steady-state leakage rates for the cases of unsaturated zones with different soil types and thicknesses. The results of the simulations demonstrate that harmonic mean hydraulic conductivity of coarse textured vadose zones is 3-4 orders of magnitude less than saturated hydraulic conductivity; whereas, the difference is only one order of magnitude for fine textured vadose zones. For both coarse and fine textured vadose zones, the effective hydraulic conductivity of the barrier system and the leakage rate to an underlying aquifer increases with increasing thickness of the vadose zone and ultimately reaches an asymptotic value for a coarse textured vadose zone thickness of about 10m and a fine textured vadose zone thickness of about 5m. Therefore, the fine and coarse textured vadose zones thicker than about 5m and 10m, respectively, act as an effective part of the barrier systems examined. Although the thickness of vadose zone affects the effective hydraulic conductivity of the overall barrier system, the results demonstrated that the hydraulic conductivity of the CCL is the dominant factor controlling the steady-state leakage rates through barrier systems having single low permeability clay layers.

  19. Road marking features extraction using the VIAPIX® system

    Science.gov (United States)

    Kaddah, W.; Ouerhani, Y.; Alfalou, A.; Desthieux, M.; Brosseau, C.; Gutierrez, C.

    2016-07-01

    Precise extraction of road marking features is a critical task for autonomous urban driving, augmented driver assistance, and robotics technologies. In this study, we consider an autonomous system allowing us lane detection for marked urban roads and analysis of their features. The task is to relate the georeferencing of road markings from images obtained using the VIAPIX® system. Based on inverse perspective mapping and color segmentation to detect all white objects existing on this road, the present algorithm enables us to examine these images automatically and rapidly and also to get information on road marks, their surface conditions, and their georeferencing. This algorithm allows detecting all road markings and identifying some of them by making use of a phase-only correlation filter (POF). We illustrate this algorithm and its robustness by applying it to a variety of relevant scenarios.

  20. Military personnel recognition system using texture, colour, and SURF features

    Science.gov (United States)

    Irhebhude, Martins E.; Edirisinghe, Eran A.

    2014-06-01

    This paper presents an automatic, machine vision based, military personnel identification and classification system. Classification is done using a Support Vector Machine (SVM) on sets of Army, Air Force and Navy camouflage uniform personnel datasets. In the proposed system, the arm of service of personnel is recognised by the camouflage of a persons uniform, type of cap and the type of badge/logo. The detailed analysis done include; camouflage cap and plain cap differentiation using gray level co-occurrence matrix (GLCM) texture feature; classification on Army, Air Force and Navy camouflaged uniforms using GLCM texture and colour histogram bin features; plain cap badge classification into Army, Air Force and Navy using Speed Up Robust Feature (SURF). The proposed method recognised camouflage personnel arm of service on sets of data retrieved from google images and selected military websites. Correlation-based Feature Selection (CFS) was used to improve recognition and reduce dimensionality, thereby speeding the classification process. With this method success rates recorded during the analysis include 93.8% for camouflage appearance category, 100%, 90% and 100% rates of plain cap and camouflage cap categories for Army, Air Force and Navy categories, respectively. Accurate recognition was recorded using SURF for the plain cap badge category. Substantial analysis has been carried out and results prove that the proposed method can correctly classify military personnel into various arms of service. We show that the proposed method can be integrated into a face recognition system, which will recognise personnel in addition to determining the arm of service which the personnel belong. Such a system can be used to enhance the security of a military base or facility.

  1. PCA Fault Feature Extraction in Complex Electric Power Systems

    Directory of Open Access Journals (Sweden)

    ZHANG, J.

    2010-08-01

    Full Text Available Electric power system is one of the most complex artificial systems in the world. The complexity is determined by its characteristics about constitution, configuration, operation, organization, etc. The fault in electric power system cannot be completely avoided. When electric power system operates from normal state to failure or abnormal, its electric quantities (current, voltage and angles, etc. may change significantly. Our researches indicate that the variable with the biggest coefficient in principal component usually corresponds to the fault. Therefore, utilizing real-time measurements of phasor measurement unit, based on principal components analysis technology, we have extracted successfully the distinct features of fault component. Of course, because of the complexity of different types of faults in electric power system, there still exists enormous problems need a close and intensive study.

  2. Pathways and Hydrography in the Mesoamerican Barrier Reef System Part 1: Circulation

    Science.gov (United States)

    Carrillo, L.; Johns, E. M.; Smith, R. H.; Lamkin, J. T.; Largier, J. L.

    2015-10-01

    Acoustic Doppler Current Profiler (ADCP) measurements and surface drifters released from two oceanographic cruises conducted during March 2006 and January/February 2007 are used to investigate the circulation off the Mesoamerican Barrier Reef System (MBRS). We show that the MBRS circulation can be divided into two distinct regimes, a northern region dominated by the strong, northward-flowing Yucatan Current, and a southern region with weaker southward coastal currents and the presence of the Honduras Gyre. The latitude of impingement of the Cayman Current onto the coastline varies with time, and creates a third region, which acts as a boundary between the northern and southern circulation regimes. This circulation pattern yields two zones in terms of dispersal, with planktonic propagules in the northern region being rapidly exported to the north, whereas plankton in the southern and impingement regions may be retained locally or regionally. The latitude of the impingement region shifts interannually and intra-annually up to 3° in latitude. Sub-mesoscale features are observed in association with topography, e.g., flow bifurcation around Cozumel Island, flow wake north of Chinchorro Bank and separation of flow from the coast just north of Bahia de la Ascencion. This third feature is evident as cyclonic recirculation in coastal waters, which we call the Ascencion-Cozumel Coastal Eddy. An understanding of the implications of these different circulation regimes on water mass distributions, population connectivity, and the fate of land-based pollutants in the MBRS is critically important to better inform science-based resource management and conservation plans for the MBRS coral reefs.

  3. HYBRID FEATURE SELECTION ALGORITHM FOR INTRUSION DETECTION SYSTEM

    Directory of Open Access Journals (Sweden)

    Seyed Reza Hasani

    2014-01-01

    Full Text Available Network security is a serious global concern. Usefulness Intrusion Detection Systems (IDS are increasing incredibly in Information Security research using Soft computing techniques. In the previous researches having irrelevant and redundant features are recognized causes of increasing the processing speed of evaluating the known intrusive patterns. In addition, an efficient feature selection method eliminates dimension of data and reduce redundancy and ambiguity caused by none important attributes. Therefore, feature selection methods are well-known methods to overcome this problem. There are various approaches being utilized in intrusion detections, they are able to perform their method and relatively they are achieved with some improvements. This work is based on the enhancement of the highest Detection Rate (DR algorithm which is Linear Genetic Programming (LGP reducing the False Alarm Rate (FAR incorporates with Bees Algorithm. Finally, Support Vector Machine (SVM is one of the best candidate solutions to settle IDSs problems. In this study four sample dataset containing 4000 random records are excluded randomly from this dataset for training and testing purposes. Experimental results show that the LGP_BA method improves the accuracy and efficiency compared with the previous related research and the feature subcategory offered by LGP_BA gives a superior representation of data.

  4. Resonance flourescence in atomic coherent systems spectral features

    CERN Document Server

    Sandhya, S N

    1999-01-01

    We study resonance flourescence in a four level ladder system and illustrate some novel features due to quantum interference and atomic coherence effects. We find that under three photon resonant conditions, in some region of the parameter space of the rabi frequencies $\\Omega_1,\\Omega_2,\\Omega_3$, emission is dominantly by the level 4 at the line center even though there is an almost equal distribution of populations in all the levels. As one increases 'dynamically collapses' to a two level system. The steady state populations and the the resonance flourescence from all the levels provide adequate evidence to this effect.

  5. Wavelet features for failure detection and identification in vibration systems

    Science.gov (United States)

    Deckert, James C.; Rhenals, Alonso E.; Tenney, Robert R.; Willsky, Alan S.

    1992-12-01

    The result of this effort is an extremely flexible and powerful methodology for failure detection and identification (FDI) in vibrating systems. The essential elements of this methodology are: (1) an off-line set of techniques to identify high-energy, statistically significant features in the continuous wavelet transform (CWT); (2) a CWT-based preprocessor to extract the most useful features from the sensor signal; and (3) simple artificial neural networks (incorporating a mechanism to defer any decision if the current feature sample is determined to be ambiguous) for the subsequent classification task. For the helicopter intermediate gearbox test-stand data and centrifugal and fire pump shipboard (mild operating condition) data used, the algorithms designed using this method achieved perfect detection performance (1.000 probability of detection, and 0.000 false alarm probability), with a probability less than 0.04 that a decision would be deferred-based on only 500 milliseconds of data from each sample case. While this effort shows the exceptional promise of our wavelet-based method for FDI in vibrating systems, more demanding applications, which also have other sources of high-energy vibration, raise additional technical issues that could provide the focus for a Phase 2 effort.

  6. Some Features on Current Pension System Reform in Latin America Some Features on Current Pension System Reform in Latin America

    OpenAIRE

    Andras Uthoff Botka

    1994-01-01

    The heterogenous nature of their population is an important feature of Latin American and Caribbean countries. Overall demographic transition is late and lagged within countries in some population groups: aging is taking place at a relatively fast pace, with yet a large share of the labour force in informal sector with no social security coverage and also growing at high rates. The challenge to pension systems is to improve their performance within societies with a large incidence of poverty,...

  7. Socio-cultural barriers to the development of a sustainable energy system - the case of hydrogen

    DEFF Research Database (Denmark)

    Petersen, Lars Kjerulf; Andersen, Anne Holst

    Any transition to a more sustainable energy system, radically reducing greenhouse gas emissions, is bound to run in to a host of different barriers - technological and economic, but also socio-cultural. This will also be the case for any large-scale application of hydrogen as energy carrier......, especially if the system is going to be based on renewable energy sources. The aim of these research notes is to review and discuss major socio-cultural barriers to new forms of energy supply in general and to hydrogen specifically. Reaching sufficient reductions in greenhouse gas emissions may require more...

  8. A method of providing a barrier in a fracture-containing system

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention relates to a method of providing a barrier in a fracture-containing system, comprising: i) Providing a treatment fluid comprising: a) a base fluid; b) an elastomeric material, wherein said elastomeric material comprises at least one polymer capable of crosslinking into an el......The present invention relates to a method of providing a barrier in a fracture-containing system, comprising: i) Providing a treatment fluid comprising: a) a base fluid; b) an elastomeric material, wherein said elastomeric material comprises at least one polymer capable of crosslinking...

  9. Unique Features and Spacecraft Applications of Dynamic Isotope Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    Raab, B.

    1982-01-01

    The dynamic isotope power system represents the most recent attempt to develop a heat-engine generator for space electric power. A major objective in this most recent effort was to increase the power and to reduce the cost of nuclear space power systems to the point where the unique features of this power source could be brought to bear for Earth-orbit missions which could benefit therefrom. This objective was largely achieved; both weight and cost of the dynamic isotope systems are comparable to solar power systems. The dynamic isotope power system, designed for spacecraft requiring prime power in the 500-2000 W range, has been successfully built and ground tested. A number of studies, summarized herein, have demonstrated the advantages of using such a power system instead of the conventional solar system for a variety of Earth-orbit missions. These advantages stem from the unique nature of the dynamic isotope system, different in kind from solar power systems. As a result, in many cases, the spacecraft design can be significantly simplified and more closely harmonized with mission requirements. This overall advantage can be crucial in missions which have stringent pointing, stability, viewing, and/or positioning requirements.

  10. Online approach to feature interaction problems in middleware based system

    Institute of Scientific and Technical Information of China (English)

    HUANG Gang; LIU XuanZhe; MEI Hong

    2008-01-01

    As a popular infrastructure for distributed systems running on the Internet, middle-ware has to support much more diverse and complex interactions for coping with the drastically increasing demand on information technology and the extremely open and dynamic nature of the Internet. These supporting mechanisms facilitate the development, deployment, and integration of distributed systems, as well as increase the occasions for distributed systems to interact in an undesired way. The undesired interactions may cause serious problems, such as quality violation, function loss, and even system crash. In this paper, the problem is studied from the perspective of the feature interaction problem (FIP) in telecom, and an online ap-proach to the detection and solution on runtime systems is proposed. Based on a classification of middleware enabled interactions, the existence of FIP in middle-ware based systems is illustrated by four real cases and a conceptual comparison between middleware based systems and telecom systems. After that, runtime soft-ware architecture is employed to facilitate the online detection and solution of FIP. The approach is demonstrated on J2EE (Java 2 Platform Enterprise Edition) and applied to detect and resolve all of the four real cases.

  11. Radiological features of uncommon aneurysms of the cardiovascular system

    Institute of Scientific and Technical Information of China (English)

    Kevin Kalisz; Prabhakar Rajiah

    2016-01-01

    Although aortic aneurysms are the most common type encountered clinically, they do not span the entire spectrum of possible aneurysms of the cardiovascular system. As cross sectional imaging techniques with cardiac computed tomography and cardiac magnetic resonance imaging continue to improve and becomes more commonplace, once rare cardiovascular aneurysms are being encountered at higher rates. In this review, a series of uncommon, yet clinically important, cardiovascular aneurysms will be presented with review of epidemiology, clinical presentation and complications, imaging features and relevant differential diagnoses, and aneurysm management.

  12. Progress of the AVNG System - Attribute Verification System with Information Barriers for Mass Isotopics Measurements.

    Energy Technology Data Exchange (ETDEWEB)

    Budnikov, D. (Dmitry); Bulatov, M. (Mikhail); Jarikhine, I. (Igor); Lebedev, B. (Boris); Livke, A. (Alexander); Modenov, A.; Morkin, A. (Anton); Razinkov, S. (Sergei); Tsaregorodtsev, D. (Dmitry); Vlokh, A. (Andrey); Yakovleva, S. (Svetlana); Elmont, T. H. (Timothy H.); Langner, D. C. (Diana C.); MacArthur, D. W. (Duncan W.); Mayo, D. R. (Douglas R.); Smith, M. K. (Morag K.); Luke, S. J. (S. John)

    2005-01-01

    An attribute verification system (AVNG) with information barriers for mass and isotopics measurements has been designed and its fabrication is nearly completed. The AVNG is being built by scientists at the Russian Federal Nuclear Center-VNIIEF, with support of Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). Such a system could be used to verify the presence of several unclassified attributes of classified material with no classified information release. The system is comprised of a neutron multiplicity counter and gamma-spectrometry system based on a high purity germanium gamma detector (nominal relative efficiency @ 1332 keV 50%) and digital gamma-ray spectrometer DSPEC{sup PLUS}. The neutron multiplicity counter is a three ring counter with 164 {sup 3}He tubes. The system was designed to measure prototype containers 491 mm in diameter and 503 mm high. This paper provides a brief history of the project and documents the progress of this effort with drawings and photographs.

  13. PROGRESS OF THE AVNG SYSTEM - ATTRIBUTE VERIFICATION SYSTEM WITH INFORMATION BARRIERS FOR MASS AND ISOTOPICS MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Budnikov, D; Bulatov, M; Jarikhine, I; Lebedev, B; Livke, A; Modenov, A; Morkin, A; Razinkov, S; Safronov, S; Tsaregorodtsev, D; Vlokh, A; Yakovleva, S; Elmont, T; Langner, D; MacArthur, D; Mayo, D; Smith, M; Luke, S J

    2005-05-27

    An attribute verification system (AVNG) with information barriers for mass and isotopics measurements has been designed and its fabrication is nearly completed. The AVNG is being built by scientists at the Russian Federal Nuclear Center-VNIIEF, with support of Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). Such a system could be used to verify the presence of several unclassified attributes of classified material with no classified information release. The system is comprised of a neutron multiplicity counter and gamma-spectrometry system based on a high purity germanium gamma detector (nominal relative efficiency {at} 1332 keV 50%) and digital gamma-ray spectrometer DSPEC{sup PLUS}. The neutron multiplicity counter is a three ring counter with 164 {sup 3}He tubes. The system was designed to measure prototype containers 491 mm in diameter and 503 mm high. This paper provides a brief history of the project and documents the progress of this effort with drawings and photographs.

  14. Advanced thermal barrier system bond coatings for use on Ni, Co-, and Fe-base alloy substrates

    Science.gov (United States)

    Stecura, S.

    1985-01-01

    New and improved Ni-, Co-, and Fe-base bond coatings have been identified for the ZrO2-Y2O3 thermal barrier coatings to be used on NI-, Co-, and Fe-base alloy substrates. These bond coatings were evaluated in a cyclic furnace between 1120 and 1175 C. It was found that MCrAlYb (where M = Ni, Co, or Fe) bond coating thermal barrier systems. The longest life was obtained with the FeCrAlYb thermal barrier system followed by NiCrAlYb and CoCrAlYb thermal barrier systems in that order.

  15. Feature Space Mapping as a universal adaptive system

    Science.gov (United States)

    Duch, Włodzisław; Diercksen, Geerd H. F.

    1995-06-01

    The most popular realizations of adaptive systems are based on the neural network type of algorithms, in particular feedforward multilayered perceptrons trained by backpropagation of error procedures. In this paper an alternative approach based on multidimensional separable localized functions centered at the data clusters is proposed. In comparison with the neural networks that use delocalized transfer functions this approach allows for full control of the basins of attractors of all stationary points. Slow learning procedures are replaced by the explicit construction of the landscape function followed by the optimization of adjustable parameters using gradient techniques or genetic algorithms. Retrieving information does not require searches in multidimensional subspaces but it is factorized into a series of one-dimensional searches. Feature Space Mapping is applicable to learning not only from facts but also from general laws and may be treated as a fuzzy expert system (neurofuzzy system). The number of nodes (fuzzy rules) is growing as the network creates new nodes for novel data but the search time is sublinear in the number of rules or data clusters stored. Such a system may work as a universal classificator, approximator and reasoning system. Examples of applications for the identification of spectra (classification), intelligent databases (association) and for the analysis of simple electrical circuits (expert system type) are given.

  16. An Activity Theory Approach to Analyze Barriers to a Virtual Management Information Systems (MIS) Curriculum

    Science.gov (United States)

    Jaradat, Suhair; Qablan, Ahmad; Barham, Areej

    2011-01-01

    This paper explains how the activity theory is used as a framework to analyze the barriers to a virtual Management Information Stream (MIS) Curriculum in Jordanian schools, from both the sociocultural and pedagogical perspectives. Taking the activity system as a unit of analysis, this study documents the processes by which activities shape and are…

  17. The immune system mediates blood-brain barrier damage; Possible implications for pathophysiology of neuropsychiatric illnesses

    NARCIS (Netherlands)

    VanderWerf, YD; DeJongste, MJL; terHorst, GJ

    1995-01-01

    The immune system mediates blood-brain barrier damage; possible implications for pathophysiology of neuropsychiatric illnesses. In this investigation the effects of immune activation on the brain are characterized In order to study this, we used a model for chronic immune activation, the myocardial

  18. Underutilization of Mental Health Services among College Students: An Examination of System-Related Barriers

    Science.gov (United States)

    Marsh, Carey N.; Wilcoxon, S. Allen

    2015-01-01

    Despite the documented benefits of counseling and mental health services on academic performance and degree attainment, only about 10% of psychologically distressed college students ever seek professional help. This investigation examined mental health care system-related barriers that might distinguish help seekers from nonhelp seekers among…

  19. FEATURES, EVENTS, AND PROCESSES: SYSTEM-LEVEL AND CRITICALITY

    Energy Technology Data Exchange (ETDEWEB)

    D.L. McGregor

    2000-12-20

    The primary purpose of this Analysis/Model Report (AMR) is to identify and document the screening analyses for the features, events, and processes (FEPs) that do not easily fit into the existing Process Model Report (PMR) structure. These FEPs include the 3 1 FEPs designated as System-Level Primary FEPs and the 22 FEPs designated as Criticality Primary FEPs. A list of these FEPs is provided in Section 1.1. This AMR (AN-WIS-MD-000019) documents the Screening Decision and Regulatory Basis, Screening Argument, and Total System Performance Assessment (TSPA) Disposition for each of the subject Primary FEPs. This AMR provides screening information and decisions for the TSPA-SR report and provides the same information for incorporation into a project-specific FEPs database. This AMR may also assist reviewers during the licensing-review process.

  20. Thermal and Environmental Barrier Coating Development for Advanced Propulsion Engine Systems

    Science.gov (United States)

    Zhu, Dongming; Miller, Robert A.; Fox, Dennis S.

    2008-01-01

    Ceramic thermal and environmental barrier coatings (TEBCs) are used in gas turbine engines to protect engine hot-section components in the harsh combustion environments, and extend component lifetimes. Advanced TEBCs that have significantly lower thermal conductivity, better thermal stability and higher toughness than current coatings will be beneficial for future low emission and high performance propulsion engine systems. In this paper, ceramic coating design and testing considerations will be described for turbine engine high temperature and high-heat-flux applications. Thermal barrier coatings for metallic turbine airfoils and thermal/environmental barrier coatings for SiC/SiC ceramic matrix composite (CMC) components for future supersonic aircraft propulsion engines will be emphasized. Further coating capability and durability improvements for the engine hot-section component applications can be expected by utilizing advanced modeling and design tools.

  1. Case study of a novel geocomposite barrier system for hydrocarbon containment on Brevoort Island

    Energy Technology Data Exchange (ETDEWEB)

    Bathurst, R.J.; Zeeb, B.; Reimer, K. [Royal Military Coll. of Canada, Kingston, ON (Canada); Rowe, R.K. [Queen' s Univ., Kingston, ON (Canada)

    2005-07-01

    North Warning System Office has undertaken a program focused on the cleanup of Canadian District Early Warning Line and Pole Vault sites located on the Canadian sub-Arctic and Arctic coastline. The implementation plan emphasizes cost-effective methods of preventing the movement of chemical contaminants into the ecosystem. This paper describes remediation steps that were taken to restrict the migration of a hydrocarbon plume before the excavation of contaminated ground at a Pole Vault site on Brevoort Island. This is the first published field application of a fluorinated geomembrane. A composite liner consisting of fluorine surface-treated polyethylene geomembrane and a geosynthetic clay liner was chosen as a barrier against hydrocarbon migration until full remediation measures could be applied. Design details, selection criteria and various challenges in the installation procedure were presented. Due to the remoteness of the location and the extremes of temperature, a site monitoring program was also initiated. Details of the programs were also presented, along with details of a parallel program of laboratory testing, initiated to investigate the long-term effects of contact with jet fuel on specimens of the barrier components as well as freeze-thaw and general lower temperatures. Results indicated that the barrier system was performing as planned. Laboratory tests indicated that the geosynthetic materials selected for the Brevoort site were expected to maintain low rates of hydrocarbon diffusion and advection beyond the original design life of the barrier system. 14 refs., 10 figs.

  2. Application of CFRP with High Hydrogen Gas Barrier Characteristics to Fuel Tanks of Space Transportation System

    Science.gov (United States)

    Yonemoto, Koichi; Yamamoto, Yuta; Okuyama, Keiichi; Ebina, Takeo

    In the future, carbon fiber reinforced plastics (CFRPs) with high hydrogen gas barrier performance will find wide applications in all industrial hydrogen tanks that aim at weight reduction; the use of such materials will be preferred to the use of conventional metallic materials such as stainless steel or aluminum. The hydrogen gas barrier performance of CFRP will become an important issue with the introduction of hydrogen-fuel aircraft. It will also play an important role in realizing fully reusable space transportation system that will have high specific tensile CFRP structures. Such materials are also required for the manufacture of high-pressure hydrogen gas vessels for use in the fuel cell systems of automobiles. This paper introduces a new composite concept that can be used to realize CFRPs with high hydrogen gas barrier performance for applications in the cryogenic tanks of fully reusable space transportation system by the incorporation of a nonmetallic crystal layer, which is actually a dense and highly oriented clay crystal laminate. The preliminary test results show that the hydrogen gas barrier characteristics of this material after cryogenic heat shocks and cyclic loads are still better than those of other polymer materials by approximately two orders of magnitude.

  3. Drug Delivery Systems, CNS Protection, and the Blood Brain Barrier

    Directory of Open Access Journals (Sweden)

    Ravi Kant Upadhyay

    2014-01-01

    Full Text Available Present review highlights various drug delivery systems used for delivery of pharmaceutical agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic substances through the endothelial capillaries (BBB for CNS therapeutics. In addition, the use of ultrasound in delivery of therapeutic agents/biomolecules such as proline rich peptides, prodrugs, radiopharmaceuticals, proteins, immunoglobulins, and chimeric peptides to the target sites in deep tissue locations inside tumor sites of brain has been explained. In addition, therapeutic applications of various types of nanoparticles such as chitosan based nanomers, dendrimers, carbon nanotubes, niosomes, beta cyclodextrin carriers, cholesterol mediated cationic solid lipid nanoparticles, colloidal drug carriers, liposomes, and micelles have been discussed with their recent advancements. Emphasis has been given on the need of physiological and therapeutic optimization of existing drug delivery methods and their carriers to deliver therapeutic amount of drug into the brain for treatment of various neurological diseases and disorders. Further, strong recommendations are being made to develop nanosized drug carriers/vehicles and noninvasive therapeutic alternatives of conventional methods for better therapeutics of CNS related diseases. Hence, there is an urgent need to design nontoxic biocompatible drugs and develop noninvasive delivery methods to check posttreatment clinical fatalities in neuropatients which occur due to existing highly toxic invasive drugs and treatment methods.

  4. FEATURES OF THE PROCESS MODEL FOR PENITENTIARY EDUCATION SYSTEM DIVERSIFICATION

    Directory of Open Access Journals (Sweden)

    Neile Kayumovna Schepkina

    2014-01-01

    Full Text Available The article covers features of the process model for penitentiary education system diversification. Issues of prison inmate education are of contemporary relevance over the past 30 years since criminal-executive system has undergone a number of changes due to changes and amendments to criminal laws and rules of proceedings, including those affected by international standards, European Prison Rules ensuring the rights of imprisoned persons to education. Russian criminal-executive, court supervision and correctional system adopted to have been implemented till 2020 provides qualitative changes in approaches related to practices of serving sentences and measures to prevent recidivism.Creating a set of incentives for social adaptation of a special group of inmates, while serving their sentences and after it, is the basic category in the range of initiatives that currently have been considered in terms of developing penitentiary system. One of the most significant ones among them is the incentive to take advantage of the educational opportunities available to them in prison.

  5. Monitoring and analyzing features of electrical power quality system performance

    Directory of Open Access Journals (Sweden)

    Genci Sharko

    2010-06-01

    Full Text Available Power quality is a set of boundaries that allows electrical systems to function in their intended manner without significant loss of performance or life. The term is used to describe electric power that drives an electrical load and the load's ability to function properly with that electric power. Without the proper quality of the power, an electrical device may malfunction, fail prematurely or not operate at all. There are many reasons why the electric power can be of poor quality and many more causes of such poor quality power. Power quality of power systems, which affects all connected electrical and electronic equipment, is a measure of deviations in voltages, currents, frequency, temperatures, winding forces and torques of particular supply systems and their components. In recent years, a considerable increase in nonlinear loads has been experienced; in particular distributed loads, such as computers, monitors and lighting, and distributed sources. The aim of this paper is to display a way of monitoring and analyzing features of electrical power quality system. As a monitoring example is taken output from power transformer rated at 320 kVA, part of distribution grid of Durres City in Albania.

  6. Acanthamoeba produces disseminated infection in locusts and traverses the locust blood-brain barrier to invade the central nervous system

    Directory of Open Access Journals (Sweden)

    Kirk Ruth

    2010-07-01

    Full Text Available Abstract Background Many aspects of Acanthamoeba granulomatous encephalitis remain poorly understood, including host susceptibility and chronic colonization which represent important features of the spectrum of host-pathogen interactions. Previous studies have suggested locusts as a tractable model in which to study Acanthamoeba pathogenesis. Here we determined the mode of parasite invasion of the central nervous system (CNS. Results Using Acanthamoeba isolates belonging to the T1 and T4 genotypes, the findings revealed that amoebae induced sickness behaviour in locusts, as evidenced by reduced faecal output and weight loss and, eventually, leading to 100% mortality. Significant degenerative changes of various tissues were observed by histological sectioning. Both isolates produced disseminated infection, with viable amoebae being recovered from various tissues. Histological examination of the CNS showed that Acanthamoeba invaded the locust CNS, and this is associated with disruption of the perineurium cell/glial cell complex, which constitutes the locust blood-brain barrier. Conclusions This is the first study to demonstrate that Acanthamoeba invades locust brain by modulating the integrity of the insect's blood-brain barrier, a finding that is consistent with the human infection. These observations support the idea that locusts provide a tractable model to study Acanthamoeba encephalitis in vivo. In this way the locust model may generate potentially useful leads that can be tested subsequently in mammalian systems, thus replacing the use of vertebrates at an early stage, and reducing the numbers of mammals required overall.

  7. Fault Feature Analysis of a Cracked Gear Coupled Rotor System

    Directory of Open Access Journals (Sweden)

    Hui Ma

    2014-01-01

    Full Text Available Considering the misalignment of gear root circle and base circle and accurate transition curve, an improved mesh stiffness model for healthy gear is proposed, and it is validated by comparison with the finite element method. On the basis of the improved method, a mesh stiffness model for a cracked gear pair is built. Then a finite element model of a cracked gear coupled rotor system in a one-stage reduction gear box is established. The effects of crack depth, width, initial position, and crack propagation direction on gear mesh stiffness, fault features in time domain and frequency domain, and statistical indicators are investigated. Moreover, fault features are also validated by experiment. The results show that the improved mesh stiffness model is more accurate than the traditional mesh stiffness model. When the tooth root crack appears, distinct impulses are found in time domain vibration responses, and sidebands appear in frequency domain. Amplitudes of all the statistical indicators ascend gradually with the growth of crack depth and width, decrease with the increasing crack initial position angle, and firstly increase and then decrease with the growth of propagation direction angle.

  8. Quantum entanglement for systems of identical bosons: I. General features

    Science.gov (United States)

    Dalton, B. J.; Goold, J.; Garraway, B. M.; Reid, M. D.

    2017-02-01

    These two accompanying papers are concerned with two mode entanglement for systems of identical massive bosons and the relationship to spin squeezing and other quantum correlation effects. Entanglement is a key quantum feature of composite systems in which the probabilities for joint measurements on the composite sub-systems are no longer determined from measurement probabilities on the separate sub-systems. There are many aspects of entanglement that can be studied. This two-part review focuses on the meaning of entanglement, the quantum paradoxes associated with entangled states, and the important tests that allow an experimentalist to determine whether a quantum state—in particular, one for massive bosons is entangled. An overall outcome of the review is to distinguish criteria (and hence experiments) for entanglement that fully utilize the symmetrization principle and the super-selection rules that can be applied to bosonic massive particles. In the first paper (I), the background is given for the meaning of entanglement in the context of systems of identical particles. For such systems, the requirement is that the relevant quantum density operators must satisfy the symmetrization principle and that global and local super-selection rules prohibit states in which there are coherences between differing particle numbers. The justification for these requirements is fully discussed. In the second quantization approach that is used, both the system and the sub-systems are modes (or sets of modes) rather than particles, particles being associated with different occupancies of the modes. The definition of entangled states is based on first defining the non-entangled states—after specifying which modes constitute the sub-systems. This work mainly focuses on the two mode entanglement for massive bosons, but is put in the context of tests of local hidden variable theories, where one may not be able to make the above restrictions. The review provides the detailed

  9. Frictional energy barrier and blocking temperature in water molecules and carbon nanotubes system

    Science.gov (United States)

    Zhang, Jianwei; Li, Jiaxi; Li, Wenfeng

    2015-03-01

    Water transport through hydrophobic channels of single-walled carbon nanotubes has attracted a lot interests, especially, various potential applications of SWCNTs have been proposed for designing novel nanofluidic devices. By adopting Molecular dynamics method, we investigated mechanics and statistics properties of water molecules escaping from a confined single-walled carbon nanotube. From our numerical MD simulations and statistical model, we determined the friction energy barrier of water molecules in (10.10) SWCNT is 9.88 kcal/mol, and which is the minimal energy for flowing a water molecules in CNT. By only using friction energy barrier and relaxation time parameter, our model can fit all different situations MD simulation results. In order to describing the frictional lock behavior of water molecules, we introduced a new blocking temperature, below this temperature (391K for our system), water is locked in CNT due to friction energy barrier. We found that the blocking temperature is closely related to system response time, and it also shows a linear behavior to frictional energy barrier. Furthermore, we found several other interesting statistics results when a water molecules leaving SWCNTs. This work was supported by NSFC No. 11274240 and NO. 51471119.

  10. Preview control of vehicle suspension system featuring MR shock absorber

    Science.gov (United States)

    Seong, M. S.; Choi, S. B.; Cho, M. W.; Lee, H. G.

    2009-02-01

    This paper presents control performance evaluation of optimal preview control algorithm for vehicle suspension featuring MR shock absorber. The optimal preview control algorithm has several advantages such as high control performance over that which is best for a non-preview system. In order to achieve this goal, a commercial MR shock absorber, Delphi MganerideTM, which is applicable to high class passenger vehicle, is adopted and its field-dependent damping force and dynamic responses are experimentally evaluated. Then the governing equation of motion for the full-vehicle model is established and integrated with the MR shock absorber. Subsequently, optimal controller with preview control algorithm is formulated and implemented for vibration suppression of the car body. Control performance of the preview controller is evaluated for the full-vehicle model under random road condition. In addition, the control performances depending on preview distances are evaluated.

  11. Barrier Lyapunov function-based model-free constraint position control for mechanical systems

    Energy Technology Data Exchange (ETDEWEB)

    Han, Seong Ik; Ha, Hyun Uk; Lee, Jang Myung [Pusan National University, Busan (Korea, Republic of)

    2016-07-15

    In this article, a motion constraint control scheme is presented for mechanical systems without a modeling process by introducing a barrier Lyapunov function technique and adaptive estimation laws. The transformed error and filtered error surfaces are defined to constrain the motion tracking error in the prescribed boundary layers. Unknown parameters of mechanical systems are estimated using adaptive laws derived from the Lyapunov function. Then, robust control used the conventional sliding mode control, which give rise to excessive chattering, is changed to finite time-based control to alleviate undesirable chattering in the control action and to ensure finite-time error convergence. Finally, the constraint controller from the barrier Lyapunov function is designed and applied to the constraint of the position tracking error of the mechanical system. Two experimental examples for the XY table and articulated manipulator are shown to evaluate the proposed control scheme.

  12. Advanced thermal barrier system bond coatings for use on nickel-, cobalt- and iron-base alloy substrates

    Science.gov (United States)

    Stecura, S.

    1986-01-01

    New and improved Ni-, Co-, and Fe-base bond coatings have been identified for the ZrO2-Y2O3 thermal barrier coatings to be used on Ni-, Co-, and Fe-base alloy substrates. These bond coatings were evaluated in a cyclic furnace between 1120 and 1175 C. It was found that MCrAlYb (where M = Ni, Co, or Fe) bond coating thermal barrier systems have significantly longer lives than MCrAlY bond coating thermal barrier systems. The longest life was obtained with the FeCrAlYb thermal barrier system followed by NiCrAlYb and CoCrAlYb thermal barrier systems in that order.

  13. Reducing Barriers To The Use of High-Efficiency Lighting Systems

    Energy Technology Data Exchange (ETDEWEB)

    Peter Morante

    2005-12-31

    With funding from the U.S. Department of Energy (DOE), the Lighting Research Center (LRC) at Rensselaer Polytechnic Institute completed the four-year research project, Reducing Barriers to the Use of High-Efficiency Lighting Systems. The initial objectives were: (1) identifying barriers to widespread penetration of lighting controls in commercial/industrial (C/I) applications that employ fluorescent lamp technologies, and (2) making recommendations to overcome these barriers. The addition of a fourth year expanded the original project objectives to include an examination of the impact on fluorescent lamps from dimming utilizing different lamp electrode heating and dimming ratios. The scope of the project was narrowed to identify barriers to the penetration of lighting controls into commercial-industrial (C/I) applications that employ fluorescent lamp technologies, and to recommend means for overcoming these barriers. Working with lighting manufacturers, specifiers, and installers, the project identified technological and marketing barriers to the widespread use of lighting controls, specifically automatic-off controls, occupancy sensors, photosensors, dimming systems, communication protocols and load-shedding ballasts. The primary barriers identified include cost effectiveness of lighting controls to the building owner, lack of standard communication protocols to allow different part of the control system to communicate effectively, and installation and commissioning issues. Overcoming the identified barriers requires lighting control products on the market to achieve three main goals: (1) Achieve sufficient functionality to meet the key requirements of their main market. (2) Allow significant cost reduction compared to current market standard systems. Cost should consider: hardware capital cost including wiring, design time required by the specifier and the control system manufacturer, installation time required by the electrician, and commissioning time and

  14. Immunohistochemical features of progesterone receptors expression of placental barrier in women with multiple pregnancies resulting from assisted reproduction

    Directory of Open Access Journals (Sweden)

    T. D. Zadorozhna

    2016-01-01

    Full Text Available Hormonal disorders are one of the main known causes of miscarriage and preterm birth in multiple pregnancies resulting from assisted reproductive technology (ART. Progesterone and the number of its receptors play an important role in the preservation and prolongation of pregnancy and it is the pressing issue of our time. The study of placentas, as the main site of synthesis of progesterone, has high informative potential and it is the most important diagnostic object, and information received by its research is essential for the full conclusion on the causes, mechanisms, close and long-term effects of multiple pregnancy pathology. Aim. The aim of our study was to investigate immunohistochemical features of placentas from women with dichorionic diamniotic twin pregnancies in spontaneous fertilization and after use of assisted reproductive technology (ART. Methods and results. According to this goal we examined 94 women, 44 of whom had multiple pregnancies due to ART, 42 with separate multiple pregnancy and 38 women with a singleton pregnancy. We carried out clinical and statistical analysis of the course of pregnancy and childbirth in the studied groups. During the study it was found that multiple pregnancies due to assisted reproduction belong to the high risk of gestation, at which premature births occur much more frequently than in singleton pregnancies. We were the first to carry out the immunohistochemical study of placentas in which the highest expression of progesterone receptors in the nuclei of cells of decidua (45% related to the parent structure of the placenta from women with multiple pregnancies caused by ART is found. It is also found that with increasing gestational age, there has been a significant decrease in the expression of the activity of progesterone receptors (from 45 to 2.5%, regardless of the method of conception and the number of fetuses. Conclusions. The results of the study point to the definitive link of structures of

  15. Barriers in the Implementation of Health Information Systems: A Scoping Review

    Directory of Open Access Journals (Sweden)

    Florin STAMATIAN

    2013-12-01

    Full Text Available Context. A well-developed health information system which is implemented according to present standards allows a healthcare quality increase. Our study aims at providing an overview of the barriers which were encountered in the process of implementing the health information systems by reviewing the literature connected to Europe and the United States of America. Methodology. We searched within five databases (Cochrane Library, Google Scholar, PubMed, ScienceDirect and Scopus for the exact phrase ‘implementation health information system’ along with the name of each European country/USA state. Relevance was then tested by scanning titles and abstracts. The third and final step involved assessing all the articles in order to set their relevance and a data extraction tool was created, containing the name of the state/country that the article reports data on, the article citation and the challenges identified. Results. The barriers identified were classified in four major categories: technical, organizational, behavioral/human and financial. Seemingly, Europe (41 articles and USA (20 articles are facing the same issues in the implementation of a health information system. No major difference between EU and non-EU countries was found after our analysis with regards to the identified barriers. Discussion. Even if recommendations and solutions are continuously being developed in order to solve these barriers, the implementation of a new health information system must be very detailed in order to face all these problems. Additionally, further research is required in order to evaluate their impact on the successful implementation of a health information system.

  16. Some Features on Current Pension System Reform in Latin America Some Features on Current Pension System Reform in Latin America

    Directory of Open Access Journals (Sweden)

    Andras Uthoff Botka

    1994-03-01

    Full Text Available The heterogenous nature of their population is an important feature of Latin American and Caribbean countries. Overall demographic transition is late and lagged within countries in some population groups: aging is taking place at a relatively fast pace, with yet a large share of the labour force in informal sector with no social security coverage and also growing at high rates. The challenge to pension systems is to improve their performance within societies with a large incidence of poverty, emerging (and some times incipient capital markets, and increasing demands for benefits. Reform alternatives in Chile. Argentina and Colombia show that their profiles differ as the result of decisions about the adequate weighting of costs and gains in the transition from a pay-as-you go scheme to a full funded one. The heterogenous nature of their population is an important feature of Latin American and Caribbean countries. Overall demographic transition is late and lagged within countries in some population groups: aging is taking place at a relatively fast pace, with yet a large share of the labour force in informal sector with no social security coverage and also growing at high rates. The challenge to pension systems is to improve their performance within societies with a large incidence of poverty, emerging (and some times incipient capital markets, and increasing demands for benefits. Reform alternatives in Chile. Argentina and Colombia show that their profiles differ as the result of decisions about the adequate weighting of costs and gains in the transition from a pay-as-you go scheme to a full funded one.

  17. Vegetation barrier and tillage effects on runoff and sediment in an alley crop system on a Luvisol in Burkina Faso

    NARCIS (Netherlands)

    Spaan, W.P.; Sikking, A.F.S.; Hoogmoed, W.B.

    2005-01-01

    The effects of vegetation barriers and tillage on runoff and soil loss were evaluated in an alley crop system at a research station in central Burkina Faso. On a 2% slope of a sandy loam various local species (grasses, woody species and a succulent) were planted as conservation barriers in order to

  18. An Interval Type-2 Neural Fuzzy System for Online System Identification and Feature Elimination.

    Science.gov (United States)

    Lin, Chin-Teng; Pal, Nikhil R; Wu, Shang-Lin; Liu, Yu-Ting; Lin, Yang-Yin

    2015-07-01

    We propose an integrated mechanism for discarding derogatory features and extraction of fuzzy rules based on an interval type-2 neural fuzzy system (NFS)-in fact, it is a more general scheme that can discard bad features, irrelevant antecedent clauses, and even irrelevant rules. High-dimensional input variable and a large number of rules not only enhance the computational complexity of NFSs but also reduce their interpretability. Therefore, a mechanism for simultaneous extraction of fuzzy rules and reducing the impact of (or eliminating) the inferior features is necessary. The proposed approach, namely an interval type-2 Neural Fuzzy System for online System Identification and Feature Elimination (IT2NFS-SIFE), uses type-2 fuzzy sets to model uncertainties associated with information and data in designing the knowledge base. The consequent part of the IT2NFS-SIFE is of Takagi-Sugeno-Kang type with interval weights. The IT2NFS-SIFE possesses a self-evolving property that can automatically generate fuzzy rules. The poor features can be discarded through the concept of a membership modulator. The antecedent and modulator weights are learned using a gradient descent algorithm. The consequent part weights are tuned via the rule-ordered Kalman filter algorithm to enhance learning effectiveness. Simulation results show that IT2NFS-SIFE not only simplifies the system architecture by eliminating derogatory/irrelevant antecedent clauses, rules, and features but also maintains excellent performance.

  19. Imaging features of central nervous system fungal infections

    Directory of Open Access Journals (Sweden)

    Jain Krishan

    2007-01-01

    Full Text Available Fungal infections of the central nervous system (CNS are rare in the general population and are invariably secondary to primary focus elsewhere, usually in the lung or intestine. Except for people with longstanding diabetes, they are most frequently encountered in immunocompromised patients such as those with acquired immunodeficiency syndrome or after organ transplantation. Due to the lack of inflammatory response, neuroradiological findings are often nonspecific and are frequently mistaken for tuberculous meningitis, pyogenic abscess or brain tumor. Intracranial fungal infections are being identified more frequently due to the increased incidence of AIDS patients, better radiological investigations, more sensitive microbiological techniques and better critical care of moribund patients. Although almost any fungus may cause encephalitis, cryptococcal meningoencephalitis is most frequently seen, followed by aspergillosis and candidiasis. The biology, epidemiology and imaging features of the common fungal infections of the CNS will be reviewed. The radiographic appearance alone is often not specific, but the combination of the appropriate clinical setting along with computed tomography or magnetic resonance may help to suggest the correct diagnosis.

  20. Nanoparticles and blood-brain barrier: the key to central nervous system diseases.

    Science.gov (United States)

    Domínguez, Alazne; Suárez-Merino, Blanca; Goñi-de-Cerio, Felipe

    2014-01-01

    Major central nervous system disorders represent a significant and worldwide public health problem. In fact, the therapeutic success of many pharmaceuticals developed to treat central nervous system diseases is still moderate, since the blood-brain barrier (BBB) limits the access of systemically administered compounds to the brain. Therefore, they require the application of a large total dose of a drug, and cause numerous toxic effects. The development of nanotechnological systems are useful tools to deliver therapeutics and/or diagnostic probes to the brain due to nanocarriers having the potential to improve the therapeutic effect of drugs and to reduce their side effects. This review provides a brief overview of the variety of carriers employed for central nervous system drug and diagnostic probes delivery. Further, this paper focuses on the novel nanocarriers developed to enhance brain delivery across the blood-brain barrier. Special attention is paid to liposomes, micelles, polymeric and lipid-based nanoparticles, dendrimers and carbon nanotubes. The recent developments in nanocarrier implementation through size/charge optimization and surface modifications (PEGylation, targeting delivery, and coating with surfactants) have been discussed. And a detailed description of the nanoscaled pharmaceutical delivery devices employed for the treatment of central nervous system disorders have also been defined. The aim of the review is to evaluate the nanotechnology-based drug delivery strategies to treat different central nervous system disorders.

  1. Influences of specific ions in groundwater on concrete degradation in subsurface engineered barrier system.

    Science.gov (United States)

    Lin, Wen-Sheng; Liu, Chen-Wuing; Li, Ming-Hsu

    2016-01-01

    Many disposal concepts currently show that concrete is an effective confinement material used in engineered barrier systems (EBS) at a number of low-level radioactive waste (LLW) disposal sites. Cement-based materials have properties for the encapsulation, isolation, or retardation of a variety of hazardous contaminants. The reactive chemical transport model of HYDROGEOCHEM 5.0 was applied to simulate the effect of hydrogeochemical processes on concrete barrier degradation in an EBS which has been proposed to use in the LLW disposal site in Taiwan. The simulated results indicated that the main processes that are responsible for concrete degradation are the species induced from hydrogen ion, sulfate, and chloride. The EBS with the side ditch drainage system effectively discharges the infiltrated water and lowers the solute concentrations that may induce concrete degradation. The redox processes markedly influence the formations of the degradation materials. The reductive environment in the EBS reduces the formation of ettringite in concrete degradation processes. Moreover, the chemical conditions in the concrete barriers maintain an alkaline condition after 300 years in the proposed LLW repository. This study provides a detailed picture of the long-term evolution of the hydrogeochemical environment in the proposed LLW disposal site in Taiwan.

  2. Breakup mechanisms for 7Li + 197Au, 204Pb systems at sub-barrier energies

    Directory of Open Access Journals (Sweden)

    Luong D.H.

    2013-12-01

    Full Text Available Coincidence measurements of breakup fragments were carried out for the 7Li + 197Au and 204Pb systems at sub-barrier energies. The mechanisms triggering breakup, and time-scales of each process, were identified through the reaction Q-values and the relative energy of the breakup fragments. Binary breakup of 7Li were found to be predominantly triggered by nucleon transfer, with p-pickup leading to 8Be → α + α decay being the preferred breakup mode. From the time-scales of each process, the coincidence yields were separated into prompt and delayed components, allowing the identification of breakup process important in the suppression of complete fusion of 7Li at above-barrier energies.

  3. Effects of sea-level rise on barrier island groundwater system dynamics: ecohydrological implications

    Science.gov (United States)

    Masterson, John P.; Fienen, Michael N.; Thieler, E. Robert; Gesch, Dean B.; Gutierrez, Benjamin T.; Plant, Nathaniel G.

    2014-01-01

    We used a numerical model to investigate how a barrier island groundwater system responds to increases of up to 60 cm in sea level. We found that a sea-level rise of 20 cm leads to substantial changes in the depth of the water table and the extent and depth of saltwater intrusion, which are key determinants in the establishment, distribution and succession of vegetation assemblages and habitat suitability in barrier islands ecosystems. In our simulations, increases in water-table height in areas with a shallow depth to water (or thin vadose zone) resulted in extensive groundwater inundation of land surface and a thinning of the underlying freshwater lens. We demonstrated the interdependence of the groundwater response to island morphology by evaluating changes at three sites. This interdependence can have a profound effect on ecosystem composition in these fragile coastal landscapes under long-term changing climatic conditions.

  4. Symmetric splitting for the system 32S+238U at energies near and below the barrier

    Science.gov (United States)

    Freifelder, R.; Braun-Munzinger, P.; Deyoung, P.; Schicker, R.; Sen, S.; Stachel, J.

    1987-06-01

    The total capture cross section for the system 32S+238U has been measured at energies from 0.93 to 1.08 times the s-wave interaction barrier by detecting coincident fission fragments following full momentum transfer reactions. The subbarrier cross section cannot be reproduced by a one-dimensional barrier penetration model. Using a quantum mechanical coupled channels model, good agreement is obtained. The measured angular distributions of fission fragments were compared to the predictions of saddle and scission point transition state theory. Saddle point transition state model calculations fail to reproduce the data, while scission point transition state calculations are in agreement with their qualitative trend. Evidence for nonequilibrium processes is presented.

  5. Desmoid fibromatosis: MRI features of response to systemic therapy

    Energy Technology Data Exchange (ETDEWEB)

    Sheth, Pooja J.; Subhawong, Ty K. [University of Miami Miller School of Medicine/Jackson Memorial Hospital, Department of Radiology, Miami, FL (United States); Del Moral, Spencer; Wilky, Breelyn A.; Trent, Jonathan C. [University of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Division of Hematology/Oncology, Department of Medicine, Miami, FL (United States); Cohen, Jonathan [Oncology and Radiation Associates, Miami, FL (United States); Rosenberg, Andrew E. [University of Miami Miller School of Medicine, Department of Pathology, Miami, FL (United States); Temple, H.T. [Center for Orthopedic Innovations, Miami, FL (United States)

    2016-10-15

    Imaging criteria for measuring the response of desmoid fibromatosis to systemic therapy are not well established. We evaluated a series of patients with desmoids who underwent systemic therapy to document magnetic resonance imaging (MRI) features associated with a positive clinical response. This Institutional Review Board-approved retrospective study included 23 patients (mean age 40.5) with 29 extra-abdominal tumors. Therapeutic regimens included cytotoxic chemotherapy (n = 19), targeted therapy (n = 3), and nonsteroid anti-inflammatory drugs (NSAIDS; n = 1). Clinical effects were categorized as progressive disease, stable, or partial response. Maximum tumor dimension (D{sub max}), approximate tumor volume (V{sub Tumor}), and quantitative tumor T2 hyperintensity and contrast enhancement (relative to muscle) for pre- and post-treatment MRIs were compared. Three lesions progressed, 5 lesions were stable, whereas 21 showed a clinical response. D{sub max} decreased more in responders (mean -11.0 %) than in stable/progressive lesions (mean -3.6 and 0 % respectively, p = 0.28, ANOVA); by Response Evaluation Criteria in Solid Tumors (RECIST 1.1) 27 out of 29 lesions were ''stable,'' including the 3 progressive lesions. In responders, V{sub Tumor} change averaged -29.4 %, but -19.2 % and +32.5 % in stable and progressive lesions respectively (p = 0.002, ANOVA); by 3D criteria 14 out of 29 lesions showed a partial response. T2 hyperintensity decreased by 50-54 % in partial response/stable disease, but only by 10 % in progressive lesions (p = 0.049, t test). Changes in contrast enhancement ranged from -23 % to 0 %, but were not statistically significant among response groups (p = 0.37). Change in T2 hyperintensity showed a positive correlation with volumetric change (r = 0.40). Decreases in volume and T2 hyperintensity reflect the positive response of desmoid fibromatosis to systemic therapy; RECIST 1.1 criteria are not sensitive to clinically

  6. Prezygotic barriers to hybridization in marine broadcast spawners: reproductive timing and mating system variation.

    Directory of Open Access Journals (Sweden)

    Carla A Monteiro

    Full Text Available Sympatric assemblages of congeners with incomplete reproductive barriers offer the opportunity to study the roles that ecological and non-ecological factors play in reproductive isolation. While interspecific asynchrony in gamete release and gametic incompatibility are known prezygotic barriers to hybridization, the role of mating system variation has been emphasized in plants. Reproductive isolation between the sibling brown algal species Fucus spiralis, Fucus guiryi (selfing hermaphrodite and Fucus vesiculosus (dioecious was studied because they form hybrids in parapatry in the rocky intertidal zone, maintain species integrity over a broad geographic range, and have contrasting mating systems. We compared reproductive synchrony (spawning overlap between the three species at several temporal scales (yearly/seasonal, semilunar/tidal, and hourly during single tides. Interspecific patterns of egg release were coincident at seasonal (single peak in spring to early summer to semilunar timescales. Synthesis of available data indicated that spawning is controlled by semidiurnal tidal and daily light-dark cues, and not directly by semilunar cycles. Importantly, interspecific shifts in timing detected at the hourly scale during single tides were consistent with a partial ecological prezygotic hybridization barrier. The species displayed patterns of gamete release consistent with a power law distribution, indicating a high degree of reproductive synchrony, while the hypothesis of weaker selective constraints for synchrony in selfing versus outcrossing species was supported by observed spawning in hermaphrodites over a broader range of tidal phase than in outcrossers. Synchronous gamete release is critical to the success of external fertilization, while high-energy intertidal environments may offer only limited windows of reproductive opportunity. Within these windows, however, subtle variations in reproductive timing have evolved with the potential to

  7. ECG Identification System Using Neural Network with Global and Local Features

    Science.gov (United States)

    Tseng, Kuo-Kun; Lee, Dachao; Chen, Charles

    2016-01-01

    This paper proposes a human identification system via extracted electrocardiogram (ECG) signals. Two hierarchical classification structures based on global shape feature and local statistical feature is used to extract ECG signals. Global shape feature represents the outline information of ECG signals and local statistical feature extracts the…

  8. Analysis on Insulation Structure of Barrier System of Converter Transformer%换流变压器出线装置的绝缘结构分析

    Institute of Scientific and Technical Information of China (English)

    蒋蓁

    2011-01-01

    Reliability of DC barrier system is one of key points of converter transformer's R&D. DC barrier systems are imported over the years. Optimization of insulation structure of barrier system has significant influence on further speeding up localization manufacture of converter transformer in China. The operation characteristic of converter transformer was summarized, and the insulation structure of barrier system was studied. Furthermore, the calculation of electric field of insulation structure for DC barrier system was made. Converter transformer has features as high short circuit impedance, DC bias current influence, serious influence of harmonic and complicated insulation structure. Electric field analysis and calculation was carried on the basis of typical insulation structure of DC barrier system for different models under different testing condition, such as long duration AC applied voltage withstand test, DC voltage withstand test with PD measurement and polarity reversal test to summarize design concept and main points to structure of DC barrier system. Test results show that the developed insulation structure of DC barrier system is reasonable, which has been approved by the test. The same theory and method will be applied to insulation structure electric field analysis of DC barrier system of converter transformer with higher voltage level to optimize the sound insulation structure of DC barrier system.%换流变压器直流出线装置的可靠性是换流变压器研制的关键问题之一,长期以来直流出线装置依靠进口,优化出合理的直流出线装置绝缘结构对进一步促进换流变压器设备制造全面国产化具有重要的意义.笔者总结了换流变压器的运行特点,研究了直流出线装置的绝缘结构,并进行了直流出线装置绝缘结构的电场计算.换流变压器的运行特点为短路阻抗大、直流偏磁影响、谐波影响严重,绝缘结构复杂,针对典型的直流出线装置绝缘

  9. Marsh Edge Erosion Effects in Coupled Barrier Island-Marsh Systems

    Science.gov (United States)

    Lauzon, R.; Moore, L. J.; Murray, A. B.; Walters, D.; Fagherazzi, S.; Mariotti, G.

    2014-12-01

    While until recently marsh loss was largely thought to be due to an inability for vertical accretion rates to match rates of sea level rise, marsh edge erosion by wind waves is now thought to be the leading cause of marsh loss worldwide. To better understand the response of coastal ecosystems to future changes in sea level and storm intensity, we further develop the coupled barrier-island marsh evolution model GEOMBEST+. We use the relationship between wave height (and therefore energy) and fetch and wind speed to add marsh edge erosion to the model, as well as to provide a more physical formulation for bay bottom erosion. Previous research addressing marshes in isolation from barrier islands (Mariotti and Fagherazzi, 2013) suggests that the existence of a backbarrier marsh is an unstable state, tending to either grow laterally to completely fill an adjacent basin or to erode away completely. Previous results of GEOMBEST+ experiments (Walters et al., in review) suggest that couplings with an adjacent barrier island can add an additional alternate long-lasting state: a narrow marsh supported by sediment influx from overwash. Here we present the results of new GEOMBEST+ model experiments that address how the addition of lateral erosion by wind waves affects the existence and characteristics of the narrow marsh state. Specifically, we seek to address how the frequency and characteristic time and space scales of the narrow march state are affected. Model experiments also explore more broadly the importance of wind wave effects in understanding the coupled dynamics of marsh-barrier island systems.

  10. Asphalt emulsion radon barrier systems for uranium mill tailings: an overview of the technology

    Energy Technology Data Exchange (ETDEWEB)

    Baker, E.G.; Hartley, J.N.; Freeman, H.D.; Gates, T.E.; Nelson, D.A.; Dunning, R.L.

    1984-03-01

    Pacific Northwest Laboratory (PNL), under contract to the US Department of Energy (DOE) Uranium Mill Tailings Remedial Action Project (UMTRAP) office, has developed an asphalt emulsion cover system to reduce the release of radon from uranium mill tailings. The system has been field tested at Grand Junction, Colorado. Results from laboratory and field tests indicate that this system is effective in reducing radon release to near-background levels (<2.5 pCi m/sup -2/s/sup -1/) and has the properties required for long-term effectiveness and stability. Engineering specifications have been developed, and analysis indicates that asphalt emulsion covers are cost-competitive with other cover systems. This report summarizes the technology for asphalt emulsion radon barrier systems. 59 references, 45 figures, 36 tables.

  11. Fission Meter Information Barrier Attribute Measurement System: Task 1 Report: Document existing Fission Meter neutron IB system

    Energy Technology Data Exchange (ETDEWEB)

    Kerr, P. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-02-28

    An SNM attribute Information Barrier (IB) system was developed for a 2011 US/UK Exercise. The system was modified and extensively tested in a 2013-2014 US-UK Measurement Campaign. This work demonstrated rapid deployment of an IB system for potential treaty use. The system utilizes an Ortec Fission Meter neutron multiplicity counter and custom computer code. The system demonstrates a proof-of-principle automated Pu-240 mass determination with an information barrier. After a software start command is issued, the system automatically acquires and downloads data, performs an analysis, and displays the results. This system conveys the results of a Pu mass threshold measurements in a way the does not reveal sensitive information. In full IB mode, only red/green ‘lights’ are displayed in the software. In test mode, more detailed information is displayed. The code can also read in, analyze, and display results from previously acquired or simulated data. Because the equipment is commercial-off-the-shelf (COTS), the system demonstrates a low-cost short-lead-time technology for treaty SNM attribute measurements. A deployed system will likely require integration of additional authentication and tamper-indicating technologies. This will be discussed for the project in this and future progress reports.

  12. Evolution of fusion hindrance for asymmetric systems at deep sub-barrier energies

    Directory of Open Access Journals (Sweden)

    A. Shrivastava

    2016-04-01

    Full Text Available Measurements of fusion cross-sections of 7Li and 12C with 198Pt at deep sub-barrier energies are reported to unravel the role of the entrance channel in the occurrence of fusion hindrance. The onset of fusion hindrance has been clearly observed in C12+Pt198 system but not in Li7+Pt198 system, within the measured energy range. Emergence of the hindrance, moving from lighter (6,7Li to heavier (12C, 16O projectiles is explained employing a model that considers a gradual transition from a sudden to adiabatic regime at low energies. The model calculation reveals a weak effect of the damping of coupling to collective motion for the present systems as compared to that obtained for systems with heavier projectiles.

  13. Evolution of fusion hindrance for asymmetric systems at deep sub-barrier energies

    Science.gov (United States)

    Shrivastava, A.; Mahata, K.; Pandit, S. K.; Nanal, V.; Ichikawa, T.; Hagino, K.; Navin, A.; Palshetkar, C. S.; Parkar, V. V.; Ramachandran, K.; Rout, P. C.; Kumar, Abhinav; Chatterjee, A.; Kailas, S.

    2016-04-01

    Measurements of fusion cross-sections of 7Li and 12C with 198Pt at deep sub-barrier energies are reported to unravel the role of the entrance channel in the occurrence of fusion hindrance. The onset of fusion hindrance has been clearly observed in 12C +198Pt system but not in 7Li +198Pt system, within the measured energy range. Emergence of the hindrance, moving from lighter (6,7Li) to heavier (12C, 16O) projectiles is explained employing a model that considers a gradual transition from a sudden to adiabatic regime at low energies. The model calculation reveals a weak effect of the damping of coupling to collective motion for the present systems as compared to that obtained for systems with heavier projectiles.

  14. Evolution of fusion hindrance for asymmetric systems at deep sub barrier energies

    CERN Document Server

    Shrivastavaa, A; Pandit, S K; Nanal, V; Ichikawa, T; Hagino, K; Navin, A; Palshetkar, C S; Parkar, V V; Ramachandran, K; Rout, P C; Kumar, Abhinav; Chatterjee, A; Kailas, S

    2016-01-01

    Measurements of fusion cross-sections of 7Li and 12C with 198Pt at deep sub-barrier energies are reported to unravel the role of the entrance channel in the occurrence of fusion hindrance. The onset of fusion hindrance has been clearly observed in 12C + 198Pt system but not in 7Li + 198Pt system, within the measured energy range. Emergence of the hindrance, moving from lighter (6,7Li) to heavier (12C,16O) projectiles is explained employing a model that considers a gradual transition from a sudden to adiabatic regime at low energies. The model calculation reveals a weak effect of the damping of coupling to collective motion for the present systems as compared to that obtained for systems with heavier projectiles.

  15. Marketing features of dropshipping in system of e-commerce

    OpenAIRE

    Kaluzhsky, Mikhail

    2015-01-01

    Today dropshipping wins the Internet promptly and transformed to one of the basic tools of marketing in e-commerce. Marketing features, mechanisms and value dropshipping in the conditions of network economy of the XXI century reveal in article. The author carries out the comparative analysis of institutional development dropshipping in the USA, China and Russia.

  16. Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Faccini, M; Amantia, D; Vazquez-Campos, S; Aubouy, L [LEITAT Technological Center, Passeig 22 de Juliol, 218, 08221 Terrassa (Spain); Vaquero, C; Lopez de Ipina, J M, E-mail: mfaccini@leitat.org [Tecnalia, P.T. Alava - C/ Leonardo Da Vinci, 11, 01510 Minano (Alava) (Spain)

    2011-07-06

    In this article our latest advances in the development of efficient barrier systems against micro- and nano-particulate materials are presented. Nanofibrous polyamide 6 (PA6) mats were fabricated by electrospinning onto a nonwoven viscose substrate. The influence of electrospinning parameters including solution concentration, viscosity, and conductivity, were studied for the production of nonwovens with different fiber size distribution ranging from 74 to 261 nm in diameters. Moreover, the formation of nanowebs (30-40 nm) which are widely distributed among fibers was observed. By varying several process parameters, membranes with different thickness of the nanofiber layer and therefore air permeability and nanoparticle filtration efficiency were obtained.

  17. Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios

    Science.gov (United States)

    Faccini, M.; Amantia, D.; Vázquez-Campos, S.; Vaquero, C.; López de Ipiña, J. M.; Aubouy, L.

    2011-07-01

    In this article our latest advances in the development of efficient barrier systems against micro- and nano-particulate materials are presented. Nanofibrous polyamide 6 (PA6) mats were fabricated by electrospinning onto a nonwoven viscose substrate. The influence of electrospinning parameters including solution concentration, viscosity, and conductivity, were studied for the production of nonwovens with different fiber size distribution ranging from 74 to 261 nm in diameters. Moreover, the formation of nanowebs (30-40 nm) which are widely distributed among fibers was observed. By varying several process parameters, membranes with different thickness of the nanofiber layer and therefore air permeability and nanoparticle filtration efficiency were obtained.

  18. Burden of Circulatory System Diseases and Ignored Barriers ofKnowledge Translation

    Directory of Open Access Journals (Sweden)

    Hamed-Basir Ghafouri

    2012-10-01

    Full Text Available Circulatory system disease raise third highest disability-adjusted life years among Iranians and ischemic cardiac diseases are main causes for such burden. Despite available evidences on risk factors of the disease, no effective intervention was implemented to control and prevent the disease. This paper non-systematically reviews available literature on the problem, solutions, and barriers of implementation of knowledge translation in Iran. It seems that there are ignored factors such as cultural and motivational issues in knowledge translation interventions but there are hopes for implementation of started projects and preparation of students as next generation of knowledge transferors.

  19. OVERCOMING THE METER BARRIER AND THE FORMATION OF SYSTEMS WITH TIGHTLY PACKED INNER PLANETS (STIPs)

    Energy Technology Data Exchange (ETDEWEB)

    Boley, A. C. [Department of Physics and Astronomy, The University of British Columbia, 6224 Agricultural Road, Vancouver, B.C. V6T 1Z1 (Canada); Morris, M. A. [Center for Meteorite Studies, Arizona State University, P.O. Box 876004, Tempe, AZ 88287-6004 (United States); Ford, E. B. [Center for Exoplanets and Habitable Worlds, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States)

    2014-09-10

    We present a solution to the long outstanding meter barrier problem in planet formation theory. As solids spiral inward due to aerodynamic drag, they will enter disk regions that are characterized by high temperatures, densities, and pressures. High partial pressures of rock vapor can suppress solid evaporation, and promote collisions between partially molten solids, allowing rapid growth. This process should be ubiquitous in planet-forming disks, which may be evidenced by the abundant class of Systems with Tightly packed Inner Planets discovered by the NASA Kepler Mission.

  20. Role of histaminergic system in blood-brain barrier dysfunction associated with neurological disorders.

    Science.gov (United States)

    Bañuelos-Cabrera, Ivette; Valle-Dorado, María Guadalupe; Aldana, Blanca Irene; Orozco-Suárez, Sandra Adela; Rocha, Luisa

    2014-11-01

    Blood-brain barrier (BBB) disruption has been associated with several acute and chronic brain disorders such as Alzheimer's disease, Parkinson's disease and epilepsy. This represents a critical situation because damaged integrity of the BBB is related to the influx of immune mediators, plasma proteins and other outside elements from blood to the central nervous system (CNS) that may trigger a cascade of events that leads to neuroinflammation. In this review, evidence that mast cells and the release of factors such as histamine play an important role in the neuroinflammatory process associated with brain disorders such as Alzheimer's disease, Parkinson's disease and epilepsy is presented.

  1. Engineered barrier system and waste package design concepts for a potential geologic repository at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Short, D.W.; Ruffner, D.J.; Jardine, L.J.

    1991-10-01

    We are using an iterative process to develop preliminary concept descriptions for the Engineered Barrier System and waste-package components for the potential geologic repository at Yucca Mountain. The process allows multiple design concepts to be developed subject to major constraints, requirements, and assumptions. Involved in the highly interactive and interdependent steps of the process are technical specialists in engineering, metallic and nonmetallic materials, chemistry, geomechanics, hydrology, and geochemistry. We have developed preliminary design concepts that satisfy both technical and nontechnical (e.g., programmatic or policy) requirements.

  2. Reactive Transport and Coupled THM Processes in Engineering Barrier Systems (EBS)

    Energy Technology Data Exchange (ETDEWEB)

    Steefel, Carl; Rutqvist, Jonny; Tsang, Chin-Fu; Liu, Hui-Hai; Sonnenthal, Eric; Houseworth, Jim; Birkholzer, Jens

    2010-08-31

    Geological repositories for disposal of high-level nuclear wastes generally rely on a multi-barrier system to isolate radioactive wastes from the biosphere. The multi-barrier system typically consists of a natural barrier system, including repository host rock and its surrounding subsurface environment, and an engineering barrier system (EBS). EBS represents the man-made, engineered materials placed within a repository, including the waste form, waste canisters, buffer materials, backfill and seals (OECD, 2003). EBS plays a significant role in the containment and long-term retardation of radionuclide release. EBS is involved in complex thermal, hydrogeological, mechanical, chemical and biological processes, such as heat release due to radionuclide decay, multiphase flow (including gas release due to canister corrosion), swelling of buffer materials, radionuclide diffusive transport, waste dissolution and chemical reactions. All these processes are related to each other. An in-depth understanding of these coupled processes is critical for the performance assessment (PA) for EBS and the entire repository. Within the EBS group of Used Fuel Disposition (UFD) Campaign, LBNL is currently focused on (1) thermal-hydraulic-mechanical-chemical (THMC) processes in buffer materials (bentonite) and (2) diffusive transport in EBS associated with clay host rock, with a long-term goal to develop a full understanding of (and needed modeling capabilities to simulate) impacts of coupled processes on radionuclide transport in different components of EBS, as well as the interaction between near-field host rock (e.g., clay) and EBS and how they effect radionuclide release. This final report documents the progress that LBNL has made in its focus areas. Specifically, Section 2 summarizes progress on literature review for THMC processes and reactive-diffusive radionuclide transport in bentonite. The literature review provides a picture of the state-of-the-art of the relevant research areas

  3. The dynamical feature of transition of a Hamiltonian system to a dissipative system

    Institute of Scientific and Technical Information of China (English)

    Zhang Guang-Cai; Zhang Hong-Jun

    2004-01-01

    The mechanism of generation and annihilation of attractors during transition from a Hamiltonian system to a dissipative system is studied numerically using the dissipative standard map. The transient process related to the formationof attracting basins of periodic attractors is studied by discussing the evolution of the KAM tori of the standard map. The result shows that as damping increases, attractors are mainly generated from elliptic orbits of the Hamiltonian system and annihilated by colliding with unstable periodic orbits originating from the corresponding hyperbolic orbits of the Hamiltonian system. The transient process also exhibits the general feature of bifurcation.

  4. Optimization of the NiCrAl-Y/ZrO-Y2O3 thermal barrier system

    Science.gov (United States)

    Stecura, S.

    1985-01-01

    The effects of bond and thermal barrier coating compositions, thicknesses, and densities on air plasma spray deposited Ni-Cr-Al-Y/ZrO2-Y2O3 life were evaluated in cyclic furnace oxidation tests at temperatures from 1110 to 1220 C. An empirical relation was developed to give life as a function of the above parameters. The thermal barrier system tested which had the longest life consisted of Ni-35.0 wt% Cr-5.9 wt% Al-0.95 wt% Y bond coating and ZrO2-6.1 wt% Y2O3 thermal barrier coating.

  5. Smart parking barrier

    KAUST Repository

    Alharbi, Abdulrazaq M.

    2016-05-06

    Various methods and systems are provided for smart parking barriers. In one example, among others, a smart parking barrier system includes a movable parking barrier located at one end of a parking space, a barrier drive configured to control positioning of the movable parking barrier, and a parking controller configured to initiate movement of the parking barrier, via the barrier drive. The movable parking barrier can be positioned between a first position that restricts access to the parking space and a second position that allows access to the parking space. The parking controller can initiate movement of the movable parking barrier in response to a positive identification of an individual allowed to use the parking space. The parking controller can identify the individual through, e.g., a RFID tag, a mobile device (e.g., a remote control, smartphone, tablet, etc.), an access card, biometric information, or other appropriate identifier.

  6. Biosensor method and system based on feature vector extraction

    Science.gov (United States)

    Greenbaum, Elias [Knoxville, TN; Rodriguez, Jr., Miguel; Qi, Hairong [Knoxville, TN; Wang, Xiaoling [San Jose, CA

    2012-04-17

    A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

  7. Total System Performance Assessment- License Application Design Selection (LADS) Phase 1 Analysis for Higher Thermal Loa (Feature 26)

    Energy Technology Data Exchange (ETDEWEB)

    N. Erb

    1999-06-11

    The objective of this report is to evaluate the effect of potential changes to the TSPA-VA base case design on long-term repository performance. The design feature that is evaluated in this report is a higher thermal load (Feature 26 or F26). The following paragraph briefly describes the motivation for evaluating higher thermal loading. Higher thermal load has been identified as a design feature that might have a beneficial effect on long-term repository performance. A higher thermal load will increase temperatures and decrease relative humidity on the waste package surface. The decrease in relative humidity may delay the onset of corrosion, thus delaying the failure of waste packages and the release of radionuclides from the engineered barrier system (EBS). For the current calculation a thermal load of 109 MTU/acre (metric tons of uranium per acre) is considered. Two cases are evaluated, one with the base case inventory and a higher thermal load and a second with an increased inventory that would cover the current repository footprint at the higher thermal load. This report documents the modeling assumptions and calculations conducted to evaluate the long-term performance of higher thermal loading. The performance measure for this evaluation is dose-rate. Results are presented that compare the dose-rate time histories with the new design feature to that for the TSPA-VA base case calculation (CRWMS M&O, 1998a).

  8. Socio-cultural barriers to the development of a sustainable energy system - the case of hydrogen

    Energy Technology Data Exchange (ETDEWEB)

    Kjerulf Petersen, L.; Holst Andersen, A.

    2009-02-15

    Any transition to a more sustainable energy system, radically reducing greenhouse gas emissions, is bound to run in to a host of different barriers - technological and economic, but also socio-cultural. This will also be the case for any large-scale application of hydrogen as energy carrier, especially if the system is going to be based on renewable energy sources. The aim of these research notes is to review and discuss major socio-cultural barriers to new forms of energy supply in general and to hydrogen specifically. Reaching sufficient reductions in greenhouse gas emissions may require more than large-scale dissemination of renewable energy sources. Also reductions or moderations in energy demand may be necessary. Hence, a central point in the research note is to consider not only socio-cultural obstacles for changing technologies in energy production, distribution and consumption but also obstacles for changing the scale of energy consumption, i.e. moderating the growth in how much energy is consumed or even reducing consumption volumes. (au)

  9. Magnetic Materials: Novel Monitors of Long-Term Evolution of Engineered Barrier Systems

    Directory of Open Access Journals (Sweden)

    Simon L. Harley

    2016-12-01

    Full Text Available Most safety cases for the deep geological disposal of radioactive waste are reliant on the swelling of bentonite in the engineered barrier system as it saturates with groundwater. Assurance of safety therefore requires effective monitoring of bentonite saturation. The time- and fluid-dependent corrosion of synthetic magnets embedded in bentonite is demonstrated here to provide a novel and passive means of monitoring saturation. Experiments have been conducted at 70 °C in which neo magnets, AlNiCo magnets, and ferrite magnets have been reacted with saline (NaCl, KCl, CaCl2 solutions and alkaline fluids (NaOH, KOH, Ca(OH2 solutions; pH = 12 in the presence of bentonite. Nd-Fe-B magnets undergo extensive corrosion that results in a dramatic change from ferromagnetic to superparamagnetic behaviour concomitant with bentonite saturation. AlNiCo magnets in saline solutions show corrosion but only limited decreases in their magnetic intensities, and ferrite magnets are essentially unreactive on the experimental timescales, retaining their initial magnetic properties. For all magnets the impact of their corrosion on bentonite swelling is negligible; alteration of bentonite is essentially governed by the applied fluid composition. In principle, synthetic magnet arrays can, with further development, be designed and embedded in bentonite to monitor its fluid saturation without compromising the integrity of the engineered barrier system itself.

  10. Applying feature reduction analysis to a PPRLM-multiple Gaussian language identification system

    OpenAIRE

    Lucas Cuesta, Juan Manuel; Córdoba Herralde, Ricardo de; D'haro Enríquez, Luis Fernando

    2008-01-01

    This paper presents the application of a feature selection technique such as LDA to a language identification (LID) system. The baseline system consists of a PPRLM module followed by a multiple-Gaussian classifier. This classifier makes use of acoustic scores and duration features of each input utterance. We applied a dimension reduction of the feature space in order to achieve a faster and easier-trainable system. We imputed missing values of our vectors before projecting them on the new spa...

  11. [Pärtel Lippus. The acoustic features and perception of the Estonian quantity system] / Stefan Werner

    Index Scriptorium Estoniae

    Werner, Stefan

    2012-01-01

    Arvustus: Pärtel Lippus. The acoustic features and perception of the Estonian quantity system. Tartu : Tartu University Press, 2011. (Dissertationes philologiae estonicae Universitatis Tartuensis ; 29)

  12. Regulation of Copper Transport Crossing Brain Barrier Systems by Cu-ATPases: Effect of Manganese Exposure

    Science.gov (United States)

    Fu, Xue; Zhang, Yanshu; Jiang, Wendy; Monnot, Andrew Donald; Bates, Christopher Alexander; Zheng, Wei

    2014-01-01

    Regulation of cellular copper (Cu) homeostasis involves Cu-transporting ATPases (Cu-ATPases), i.e., ATP7A and ATP7B. The question as to how these Cu-ATPases in brain barrier systems transport Cu, i.e., toward brain parenchyma, cerebrospinal fluid (CSF), or blood, remained unanswered. This study was designed to characterize roles of Cu-ATPases in regulating Cu transport at the blood-brain barrier (BBB) and blood-CSF barrier (BCB) and to investigate how exposure to toxic manganese (Mn) altered the function of Cu-ATPases, thereby contributing to the etiology of Mn-induced parkinsonian disorder. Studies by quantitative real-time RT-PCR (qPCR), Western blot, and immunocytochemistry revealed that both Cu-ATPases expressed abundantly in BBB and BCB. Transport kinetic studies by in situ brain infusion and ventriculo-cisternal (VC) perfusion in Sprague Dawley rat suggested that the BBB was a major site for Cu entry into brain, whereas the BCB was a predominant route for Cu efflux from the CSF to blood. Confocal evidence showed that the presence of excess Cu or Mn in the choroid plexus cells led to ATP7A relocating toward the apical microvilli facing the CSF, but ATP7B toward the basolateral membrane facing blood. Mn exposure inhibited the production of both Cu-ATPases. Collectively, these data suggest that Cu is transported by the BBB from the blood to brain, which is mediated by ATP7A in brain capillary. By diffusion, Cu ions move from the interstitial fluid into the CSF, where they are taken up by the BCB. Within the choroidal epithelial cells, Cu ions are transported by ATP7B back to the blood. Mn exposure alters these processes, leading to Cu dyshomeostasis-associated neuronal injury. PMID:24614235

  13. The advantages and barriers in the implementation of a substance dependence treatment information system (SDTIS).

    Science.gov (United States)

    Ajami, Sima; Mellat-Karkevandi, Zahra

    2015-11-01

    Addiction is a phenomenon that causes structural changes in different systems of society. Studies show for planning of addiction prevention and treatment, it is necessary to create an information management system. Substance dependence information systems refer to systems which collect, analyse and report data related to substance dependence information. The aim of this study was to identify advantages and barriers to implement Substance Dependence Treatment Information System (SDTIS). This study was a narrative review. Our review divided into three phases: literature collection, assessing, and selection. We employed the following keywords and their combinations in different areas of articles. In this study, 22 of collected articles and reports were selected based on their relevancy. We found many advantages for a substance dependence treatment information system such as recording sufficient, complete and accurate information and easy and timely access to them and monitoring and enhancing the quality of care received by patients. But we may face some concerns for implementing this information system like taking time and funds from client services, being expensive or even problems regarding the quality of data contained in these information systems. There are some important problems in the way of implementing. In order to overcome these issues, we need to raise community awareness.

  14. The advantages and barriers in the implementation of a substance dependence treatment information system (SDTIS

    Directory of Open Access Journals (Sweden)

    Sima Ajami

    2015-01-01

    Full Text Available Addiction is a phenomenon that causes structural changes in different systems of society. Studies show for planning of addiction prevention and treatment, it is necessary to create an information management system. Substance dependence information systems refer to systems which collect, analyse and report data related to substance dependence information. The aim of this study was to identify advantages and barriers to implement Substance Dependence Treatment Information System (SDTIS. This study was a narrative review. Our review divided into three phases: literature collection, assessing, and selection. We employed the following keywords and their combinations in different areas of articles. In this study, 22 of collected articles and reports were selected based on their relevancy. We found many advantages for a substance dependence treatment information system such as recording sufficient, complete and accurate information and easy and timely access to them and monitoring and enhancing the quality of care received by patients. But we may face some concerns for implementing this information system like taking time and funds from client services, being expensive or even problems regarding the quality of data contained in these information systems. There are some important problems in the way of implementing. In order to overcome these issues, we need to raise community awareness.

  15. Degradation of Organic Compounds by Active Species Sprayed in a Dielectric Barrier Corona Discharge System

    Institute of Scientific and Technical Information of China (English)

    LI Jie; SONG Ling; LIU Qiang; QU Guangzhou; LI Guofeng; WU Yan

    2009-01-01

    Investigation was made into the degradation of organic compounds by a dielectric barrier corona discharge (DBCD) system. The DBCD, consisting of a quartz tube, a concentric high voltage electrode and a net wrapped to the external wall (used as ground electrode), was introduced to generate active species which were sprayed into the organic solution through an aerator fixed on the bottom of the tube. The effect of four factors-the discharge voltage, gas flow rate, solution conductivity, and pH of wastewater, on the degradation efficiency of phenol was assessed. The obtained results demonstrated that this process was an effective method for phenol degradation. The degradation rate was enhanced with the increase in power supplied. The degradation efficiency in alkaline conditions was higher than those in acid and neutral conditions.The optimal gas flow rate for phenol degradation in the system was 1.6 L/min, while the solution conductivity had little effect on the degradation.

  16. Advanced Oxide Material Systems for 1650 C Thermal/Environmental Barrier Coating Applications

    Science.gov (United States)

    Zhu, Dong-Ming; Fox, Dennis S.; Bansal, Narottam P.; Miller, Robert A.

    2004-01-01

    Advanced thermal and environmental barrier coatings (TEBCs) are being developed for low-emission SiC/SiC ceramic matrix composite (CMC) combustor and vane applications to extend the CMC liner and vane temperature capability to 1650 C (3000 F) in oxidizing and water-vapor-containing combustion environments. The advanced 1650 C TEBC system is required to have a better high-temperature stability, lower thermal conductivity, and more resistance to sintering and thermal stress than current coating systems under engine high-heat-flux and severe thermal cycling conditions. In this report, the thermal conductivity and water vapor stability of selected candidate hafnia-, pyrochlore- and magnetoplumbite-based TEBC materials are evaluated. The effects of dopants on the materials properties are also discussed. The test results have been used to downselect the TEBC materials and help demonstrate the feasibility of advanced 1650 C coatings with long-term thermal cycling durability.

  17. Comparing the Dimensions of Modern and Ancient Barrier Island Systems to Understand Controls on Preservation

    Science.gov (United States)

    Mulhern, J.; Johnson, C. L.; Stright, L.

    2015-12-01

    Commonly assumed to have low preservation potential, barrier islands are rarely interpreted in the rock record, and there is little consensus on the terminology and depositional models related to their interpretation. Prevalent on transgressive coastlines, the dimensions of modern barriers are used as analogs for the ancient; however, ancient examples are complicated by post-depositional processes, including thickening through amalgamation and removal by ravinement. Contrasting the dimensions of modern and ancient examples lends insight into the development and preservation of transgressive deposits, improving the ability to predict the size and distribution of barrier island sand bodies in the rock record as well as understanding the variables that control their architecture. Interpretation of barrier island deposits from the John Henry Member (Cretaceous Straight Cliffs Fm., Kaiparowits Plateau, southern Utah) motivated an investigation into both ancient and modern barrier islands. Traditional sequence stratigraphic models predict thin condensed deposition during transgression, not accounting for possible thick and laterally extensive accumulations of barrier island deposits. More recent models recognize the possible complexity and heterogeneity of transgressive deposits and the potential for barrier island accumulation. To better understand the relationship between modern and ancient barrier islands, the length (along strike), width (dip direction) and thickness (vertical) of >20 modern and >30 ancient barrier islands were compared. Ancient dimensions were gathered from the literature, while modern dimensions were aggregated from literature and a database of modern barrier islands currently being developed. Initial results suggest that ancient barrier island deposits record the motion of the shoreline during transgression. Ancient barriers are ~2-8 times wider and ~2-3 times thicker than modern islands. The dynamics of barrier island migration and sediment

  18. Regulated competition in health care: Switching and barriers to switching in the Dutch health insurance system

    Directory of Open Access Journals (Sweden)

    Rijken Mieke

    2011-05-01

    Full Text Available Abstract Background In 2006, a number of changes in the Dutch health insurance system came into effect. In this new system mobility of insured is important. The idea is that insured switch insurers because they are not satisfied with quality of care and the premium of their insurance. As a result, insurers will in theory strive for a better balance between price and quality. The Dutch changes have caught the attention, internationally, of both policy makers and researchers. In our study we examined switching behaviour over three years (2007-2009. We tested if there are differences in the numbers of switchers between groups defined by socio-demographic and health characteristics and between the general population and people with chronic illness or disability. We also looked at reasons for (not-switching and at perceived barriers to switching. Methods Switching behaviour and reasons for (not-switching were measured over three years (2007-2009 by sending postal questionnaires to members of the Dutch Health Care Consumer Panel and of the National Panel of people with Chronic illness or Disability. Data were available for each year and for each panel for at least 1896 respondents - a response of between 71% and 88%. Results The percentages of switchers are low; 6% in 2007, 4% in 2008 and 3% in 2009. Younger and higher educated people switch more often than older and lower educated people and women switch more often than men. There is no difference in the percentage of switchers between the general population and people with chronic illness or disability. People with a bad self-perceived health, and chronically ill and disabled, perceive more barriers to switching than others. Conclusion The percentages of switchers are comparable to the old system. Switching is not based on quality of care and thus it can be questioned whether it will lead to a better balance between price and quality. Although there is no difference in the frequency of switching

  19. Advances in research on labyrinth membranous barriers

    Institute of Scientific and Technical Information of China (English)

    Wenfang Sun; Wuqing Wang

    2015-01-01

    Integrity of the membranous labyrinth barrier system is of critical importance, which promotes inner ear homeostasis and maintains its features. The membranous labyrinth barrier system is divided into several subsets of barriers which, although independent from each other, are interrelated. The same substance may demonstrate different permeability characteristics through different barriers and under different conditions, while different substances can have different permeability features even in the same barrier under the same condition. All parts of the mem-branous labyrinth barrier structure, including their morphology, enzymes and channel proteins, and theirs permeability characteristics under various physiological and pathological conditions are reviewed in this paper. Infections, noise exposure, ototoxicity may all increase perme-ability of the barriers and lead to disturbances in inner ear homeostasis. Copyright © 2015 The Authors. Production & hosting by Elsevier (Singapore) Pte Ltd On behalf of PLA General Hospital Department of Otolaryngology Head and Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

  20. Quantifying system safety: A comparison of the SBOAT & Safety Barrier Manager tools

    DEFF Research Database (Denmark)

    Hansen, Zaza Nadja Lee; Duijm, Nijs Jan; Markert, Frank;

    2015-01-01

    This paper presents two software tools for analyzing safety risks, SBOAT (Stochastic BPMN Optimisation and Analysis Tool) and SBM (SafetyBarrierManagerr). SBOAT employs principles from stochastic model checking to allow for the quantitative verification of workflows. SBM supports the creation...... of valid safety-barrier diagrams and allows the quantitative analysis of the probability of all possible end states of the barrier diagram, i.e. the outcomes if one or several of the barriers fail to perform their barrier function. We compare the foundations of these tools and describe how they can be used...

  1. Effectiveness of compacted soil liner as a gas barrier layer in the landfill final cover system.

    Science.gov (United States)

    Moon, Seheum; Nam, Kyoungphile; Kim, Jae Young; Hwan, Shim Kyu; Chung, Moonkyung

    2008-01-01

    A compacted soil liner (CSL) has been widely used as a single barrier layer or a part of composite barrier layer in the landfill final cover system to prevent water infiltration into solid wastes for its acceptable hydraulic permeability. This study was conducted to test whether the CSL was also effective in prohibiting landfill gas emissions. For this purpose, three different compaction methods (i.e., reduced, standard, and modified Proctor methods) were used to prepare the soil specimens, with nitrogen as gas, and with water and heptane as liquid permeants. Measured gas permeability ranged from 2.03 x 10(-10) to 4.96 x 10(-9) cm(2), which was a magnitude of two or three orders greater than hydraulic permeability (9.60 x 10(-13) to 1.05 x 10(-11) cm(2)). The difference between gas and hydraulic permeabilities can be explained by gas slippage, which makes gas more permeable, and by soil-water interaction, which impedes water flow and then makes water less permeable. This explanation was also supported by the result that a liquid permeability measured with heptane as a non-polar liquid was similar to the intrinsic gas permeability. The data demonstrate that hydraulic requirement for the CSL is not enough to control the gas emissions from a landfill.

  2. Ultrathin, transferred layers of thermally grown silicon dioxide as biofluid barriers for biointegrated flexible electronic systems

    Science.gov (United States)

    Fang, Hui; Zhao, Jianing; Yu, Ki Jun; Song, Enming; Barati Farimani, Amir; Chiang, Chia-Han; Jin, Xin; Xue, Yeguang; Xu, Dong; Du, Wenbo; Seo, Kyung Jin; Zhong, Yiding; Yang, Zijian; Won, Sang Min; Fang, Guanhua; Choi, Seo Woo; Chaudhuri, Santanu; Huang, Yonggang; Ashraful Alam, Muhammad; Viventi, Jonathan; Aluru, N. R.; Rogers, John A.

    2016-10-01

    Materials that can serve as long-lived barriers to biofluids are essential to the development of any type of chronic electronic implant. Devices such as cardiac pacemakers and cochlear implants use bulk metal or ceramic packages as hermetic enclosures for the electronics. Emerging classes of flexible, biointegrated electronic systems demand similar levels of isolation from biofluids but with thin, compliant films that can simultaneously serve as biointerfaces for sensing and/or actuation while in contact with the soft, curved, and moving surfaces of target organs. This paper introduces a solution to this materials challenge that combines (i) ultrathin, pristine layers of silicon dioxide (SiO2) thermally grown on device-grade silicon wafers, and (ii) processing schemes that allow integration of these materials onto flexible electronic platforms. Accelerated lifetime tests suggest robust barrier characteristics on timescales that approach 70 y, in layers that are sufficiently thin (less than 1 μm) to avoid significant compromises in mechanical flexibility or in electrical interface fidelity. Detailed studies of temperature- and thickness-dependent electrical and physical properties reveal the key characteristics. Molecular simulations highlight essential aspects of the chemistry that governs interactions between the SiO2 and surrounding water. Examples of use with passive and active components in high-performance flexible electronic devices suggest broad utility in advanced chronic implants.

  3. Monitoring Local Strain in a Thermal Barrier Coating System Under Thermal Mechanical Gas Turbine Operating Conditions

    Science.gov (United States)

    Manero, Albert; Sofronsky, Stephen; Knipe, Kevin; Meid, Carla; Wischek, Janine; Okasinski, John; Almer, Jonathan; Karlsson, Anette M.; Raghavan, Seetha; Bartsch, Marion

    2015-07-01

    Advances in aircraft and land-based turbine engines have been increasing the extreme loading conditions on traditional engine components and have incited the need for improved performance with the use of protective coatings. These protective coatings shield the load-bearing super alloy blades from the high-temperature combustion gases by creating a thermal gradient over their thickness. This addition extends the life and performance of blades. A more complete understanding of the behavior, failure mechanics, and life expectancy for turbine blades and their coatings is needed to enhance and validate simulation models. As new thermal-barrier-coated materials and deposition methods are developed, strides to effectively test, evaluate, and prepare the technology for industry deployment are of paramount interest. Coupling the experience and expertise of researchers at the University of Central Florida, The German Aerospace Center, and Cleveland State University with the world-class synchrotron x-ray beam at the Advanced Photon Source in Argonne National Laboratory, the synergistic collaboration has yielded previously unseen measurements to look inside the coating layer system for in situ strain measurements during representative service loading. These findings quantify the in situ strain response on multilayer thermal barrier coatings and shed light on the elastic and nonelastic properties of the layers and the role of mechanical load and internal cooling variations on the response. The article discusses the experimental configuration and development of equipment to perform in situ strain measurements on multilayer thin coatings and provides an overview of the achievements thus far.

  4. Rheumatologists' perception of systemic lupus erythematosus quality indicators: significant interest and perceived barriers.

    Science.gov (United States)

    Casey, Carolyn; Chung, Cecilia P; Crofford, Leslie J; Barnado, April

    2017-01-01

    Differences in quality of care may contribute to health disparities in systemic lupus erythematosus (SLE). Studies show low physician adherence rates to the SLE quality indicators but do not assess physician perception of SLE quality indicators or quality improvement. Using a cross-sectional survey of rheumatologists in the southeastern USA, we assessed the perception and involvement of rheumatologists in quality improvement and the SLE quality indicators. Using electronic mail, an online survey of 32 questions was delivered to 568 rheumatologists. With a response rate of 19% (n = 106), the majority of participants were male, Caucasian, with over 20 years of experience, and seeing adult patients in an academic setting. Participants had a positive perception toward quality improvement (81%) with a majority responding that the SLE quality indicators would significantly impact quality of care (54%). While 66% of respondents were familiar with the SLE quality indicators, only 18% of respondents reported using them in everyday practice. The most commonly reported barrier to involvement in quality improvement and the SLE quality indicators was time. Rheumatologists had a positive perception of the SLE quality indicators and agreed that use of the quality indicators could improve quality of care in SLE; however, they identified time as a barrier to implementation. Future studies should investigate methods to increase use of the SLE quality indicators.

  5. Formal Modeling and Verification of Interlocking Systems Featuring Sequential Release

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2015-01-01

    In this paper, we present a method and an associated tool suite for formal verification of the new ETCS level 2 based Danish railway interlocking systems. We have made a generic and reconfigurable model of the system behavior and generic high-level safety properties. This model accommodates seque...

  6. Structural and functional features of central nervous system lymphatic vessels.

    Science.gov (United States)

    Louveau, Antoine; Smirnov, Igor; Keyes, Timothy J; Eccles, Jacob D; Rouhani, Sherin J; Peske, J David; Derecki, Noel C; Castle, David; Mandell, James W; Lee, Kevin S; Harris, Tajie H; Kipnis, Jonathan

    2015-07-16

    One of the characteristics of the central nervous system is the lack of a classical lymphatic drainage system. Although it is now accepted that the central nervous system undergoes constant immune surveillance that takes place within the meningeal compartment, the mechanisms governing the entrance and exit of immune cells from the central nervous system remain poorly understood. In searching for T-cell gateways into and out of the meninges, we discovered functional lymphatic vessels lining the dural sinuses. These structures express all of the molecular hallmarks of lymphatic endothelial cells, are able to carry both fluid and immune cells from the cerebrospinal fluid, and are connected to the deep cervical lymph nodes. The unique location of these vessels may have impeded their discovery to date, thereby contributing to the long-held concept of the absence of lymphatic vasculature in the central nervous system. The discovery of the central nervous system lymphatic system may call for a reassessment of basic assumptions in neuroimmunology and sheds new light on the aetiology of neuroinflammatory and neurodegenerative diseases associated with immune system dysfunction.

  7. A flexible micro fluid transport system featuring magnetorheological elastomer

    Science.gov (United States)

    Behrooz, Majid; Gordaninejad, Faramarz

    2016-02-01

    This study presents a flexible magnetically-actuated micro fluid transport system utilizing an isotropic magnetorheological elastomer (MRE). Theoretical modeling and analysis of this system is presented for a two-dimensional model. This fluid transport system can propel the fluid by applying a fluctuating magnetic field on the MRE. The magneto-fluid-structure interaction analysis is employed to determine movement of the solid domain and the velocity of the fluid under a controllable magnetic field. The effects of key material, geometric, and magnetic parameters on the behavior of this system are examined. It is demonstrated that the proposed system can propel the fluid unidirectionally, and the volume of the transported fluid is significantly affected by some of the design parameters.

  8. Omnidirectional vision systems calibration, feature extraction and 3D information

    CERN Document Server

    Puig, Luis

    2013-01-01

    This work focuses on central catadioptric systems, from the early step of calibration to high-level tasks such as 3D information retrieval. The book opens with a thorough introduction to the sphere camera model, along with an analysis of the relation between this model and actual central catadioptric systems. Then, a new approach to calibrate any single-viewpoint catadioptric camera is described.  This is followed by an analysis of existing methods for calibrating central omnivision systems, and a detailed examination of hybrid two-view relations that combine images acquired with uncalibrated

  9. GNIS: Geographic Names Information Systems - All features (2013)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  10. Human-interpretable feature pattern classification system using learning classifier systems.

    Science.gov (United States)

    Ebadi, Toktam; Kukenys, Ignas; Browne, Will N; Zhang, Mengjie

    2014-01-01

    Image pattern classification is a challenging task due to the large search space of pixel data. Supervised and subsymbolic approaches have proven accurate in learning a problem's classes. However, in the complex image recognition domain, there is a need for investigation of learning techniques that allow humans to interpret the learned rules in order to gain an insight about the problem. Learning classifier systems (LCSs) are a machine learning technique that have been minimally explored for image classification. This work has developed the feature pattern classification system (FPCS) framework by adopting Haar-like features from the image recognition domain for feature extraction. The FPCS integrates Haar-like features with XCS, which is an accuracy-based LCS. A major contribution of this work is that the developed framework is capable of producing human-interpretable rules. The FPCS system achieved 91 [Formula: see text] 1% accuracy on the unseen test set of the MNIST dataset. In addition, the FPCS is capable of autonomously adjusting the rotation angle in unaligned images. This rotation adjustment raised the accuracy of FPCS to 95%. Although the performance is competitive with equivalent approaches, this was not as accurate as subsymbolic approaches on this dataset. However, the benefit of the interpretability of rules produced by FPCS enabled us to identify the distribution of the learned angles-a normal distribution around [Formula: see text]-which would have been very difficult in subsymbolic approaches. The analyzable nature of FPCS is anticipated to be beneficial in domains such as speed sign recognition, where underlying reasoning and confidence of recognition needs to be human interpretable.

  11. Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features

    Directory of Open Access Journals (Sweden)

    Shi Qi

    2012-03-01

    Full Text Available Abstract Background Transmissible spongiform encephalopathy (TSE diseases are known to be zoonotic diseases that can infect different kinds of animals. The transmissibility of TSE, like that of other infectious diseases, shows marked species barrier, either being unable to infect heterologous species or difficult to form transmission experimentally. The similarity of the amino acid sequences of PrP among species is believed to be one of the elements in controlling the transmission TSE interspecies. Other factors, such as prion strains and host's microenvironment, may also participate in the process. Methods Two mouse-adapted strains 139A and ME7 were cerebrally inoculated to Golden hamsters. Presences of scrapie associate fibril (SAF and PrPSc in brains of the infected animals were tested by TEM assays and Western blots dynamically during the incubation periods. The pathogenic features of the novel prions in hamsters, including electrophoretic patterns, glycosylating profiles, immunoreactivities, proteinase K-resistances and conformational stabilities were comparatively evaluated. TSE-related neuropathological changes were assayed by histological examinations. Results After long incubation times, mouse-adapted agents 139A and ME7 induced experimental scrapie in hamsters, respectively, showing obvious spongiform degeneration and PrPSc deposits in brains, especially in cortex regions. SAF and PrPSc in brains were observed much earlier than the onset of clinical symptoms. The molecular characteristics of the newly-formed PrPSc in hamsters, 139A-ha and ME7-ha, were obviously distinct from the original mouse agents, however, greatly similar as that of a hamster-adapted scrapie strain 263 K. Although the incubation times and main disease signs of the hamsters of 139A-ha and ME7-ha were different, the pathogenic characteristics and neuropathological changes were highly similar. Conclusions This finding concludes that mouse-adapted agents 139A and ME7

  12. Changes in skin barrier during treatment with systemic alitretinoin: focus on skin susceptibility and stratum corneum ceramides

    DEFF Research Database (Denmark)

    Jungersted, J.M.; Høgh, Julie Kaae; Hellgren, Lars;

    2010-01-01

    the effect of systemic alitretinoin on skin barrier function and response to irritants, a secondary objective was to determine if changes occur in the lipid profile of stratum corneum after treatment with systemic alitretinoin. We conducted an open clinical intervention study on eight people ascribed...

  13. An object-oriented mobile health system with usability features.

    Science.gov (United States)

    Escarfullet, Krystle; Moore, Cantera; Tucker, Shari; Wei, June

    2012-01-01

    Mobile health (m-health) comprises the concept of utilising mobile devices to carry out the task of viewing electronic medical records, reserving medical appointments with a patient's medical provider and electronically refilling prescriptions. This paper aims at developing a m-health system to improve usability from a user's perspective. Specifically, it first developed a m-health model by logically linking characteristics of the m-health system together based on information flows. Then, the system requirements were collected by using a developed questionnaire. These requirements were structured and further in-depth analysis was conducted by using an object-oriented approach based on unified modelling language, such as use-case, sequence and analysis class diagrams. This research will be beneficial to decision makers and developers in the mobile healthcare industry.

  14. Crossover from Bosonic to Fermionic features in Composite Boson Systems

    CERN Document Server

    Thilagam, A

    2013-01-01

    We study the quantum dynamics of conversion of composite bosons into fermionic fragment species with increasing densities of bound fermion pairs using the open quantum system approach. The Hilbert space of $N$-state-function is decomposed into a composite boson subspace and an orthogonal fragment subspace of quasi-free fermions that enlarges as the composite boson constituents deviate from ideal boson commutation relations. The tunneling dynamics of coupled composite boson states in confined systems is examined, and the appearance of exceptional points under experimentally testable conditions (densities, lattice temperatures) is highlighted. The theory is extended to examine the energy transfer between macroscopically coherent systems such as multichromophoric macromolecules (MCMMs) in photosynthetic light harvesting complexes.

  15. New operator assistance features in the CMS Run Control System

    CERN Document Server

    Andre, Jean-marc Olivier; Branson, James; Brummer, Philipp Maximilian; Chaze, Olivier; Cittolin, Sergio; Contescu, Cristian; Craigs, Benjamin Gordon; Darlea, Georgiana Lavinia; Deldicque, Christian; Demiragli, Zeynep; Dobson, Marc; Doualot, Nicolas; Erhan, Samim; Fulcheri, Jonathan F; Gigi, Dominique; Michail Gl; adki; Glege, Frank; Gomez Ceballos, Guillelmo; Hegeman, Jeroen Guido; Holzner, Andre Georg; Janulis, Mindaugas; Jimenez Estupinan, Raul; Masetti, Lorenzo; Meijers, Franciscus; Meschi, Emilio; Mommsen, Remigius; Morovic, Srecko; O'Dell, Vivian; Orsini, Luciano; Paus, Christoph Maria Ernst; Petrova, Petia; Pieri, Marco; Racz, Attila; Reis, Thomas; Sakulin, Hannes; Schwick, Christoph; Simelevicius, Dainius; Zejdl, Petr

    2017-01-01

    The Run Control System of the Compact Muon Solenoid (CMS) experiment at CERN is a distributed Java web application running on Apache Tomcat servers. During Run-1 of the LHC, many operational procedures have been automated. When detector high voltages are ramped up or down or upon certain beam mode changes of the LHC, the DAQ system is automatically partially reconfigured with new parameters. Certain types of errors such as errors caused by single-event upsets may trigger an automatic recovery procedure. Furthermore, the top-level control node continuously performs cross-checks to detect sub-system actions becoming necessary because of changes in configuration keys, changes in the set of included front-end drivers or because of potential clock instabilities. The operator is guided to perform the necessary actions through graphical indicators displayed next to the relevant command buttons in the user interface. Through these indicators, consistent configuration of CMS is ensured. However, manually following t...

  16. On the near-barrier fusion of the proton-halo {sup 8}B + {sup 58}Ni system

    Energy Technology Data Exchange (ETDEWEB)

    Rangel, J.; Lubian, J.; Gomes, P.R.S. [Universidade Federal Fluminense, Instituto de Fisica, Gragoata, Niteroi, R.J. (Brazil); Carlson, B.V. [Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Paulo (Brazil); Chamon, L.C. [Universidade de Sao Paulo, Instituto de Fisica, CP 66318, Sao Paulo (Brazil); Gomez Camacho, A. [Instituto Nacional de Investigaciones, Departamento de Aceleradores, Apartado Postal 18-1027, C.P. 11801, Mexico, D.F. (Mexico)

    2013-05-15

    We have performed two independent calculations, without any free parameter, to predict the near-barrier fusion cross section for the proton-halo {sup 8}B + {sup 58}Ni system, for which data were recently reported. Standard coupled channel calculations predict fusion cross sections smaller than the data, while CDCC calculations for the absorption cross section (fusion + transfer + inelastic cross sections) agree with the data above the barrier, although transfer cross sections are calculated to have non-negligible cross section at this energy regime. At sub-barrier energies, region where transfer cross sections are particularly important, the CDCC calculations overpredict the data. The fusion data of the {sup 8}B + {sup 58}Ni system fail to follow the systematics of other weakly bound nuclei and the UFF curve and do not agree with the fusion data of the {sup 8}B + {sup 28}Si system. We try to explain this anomalous behaviour. (orig.)

  17. Creep Behavior of Hafnia and Ytterbium Silicate Environmental Barrier Coating Systems on SiC/SiC Ceramic Matrix Composites

    Science.gov (United States)

    Zhu, Dongming; Fox, Dennis S.; Ghosn, Louis J.; Harder, Bryan

    2011-01-01

    Environmental barrier coatings will play a crucial role in future advanced gas turbine engines because of their ability to significantly extend the temperature capability and stability of SiC/SiC ceramic matrix composite (CMC) engine components, thus improving the engine performance. In order to develop high performance, robust coating systems for engine components, appropriate test approaches simulating operating temperature gradient and stress environments for evaluating the critical coating properties must be established. In this paper, thermal gradient mechanical testing approaches for evaluating creep and fatigue behavior of environmental barrier coated SiC/SiC CMC systems will be described. The creep and fatigue behavior of Hafnia and ytterbium silicate environmental barrier coatings on SiC/SiC CMC systems will be reported in simulated environmental exposure conditions. The coating failure mechanisms will also be discussed under the heat flux and stress conditions.

  18. Formal Modeling and Verification of Interlocking Systems Featuring Sequential Release

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2014-01-01

    In this paper, we present a method and an associated tool suite for formal verification of the new ETCS level 2 based Danish railway interlocking systems. We have made a generic and reconfigurable model of the system behavior and generic high-level safety properties. This model accommodates seque...... SMT based bounded model checking (BMC) and inductive reasoning, we are able to verify the properties for model instances corresponding to railway networks of industrial size. Experiments also show that BMC is efficient for finding bugs in the railway interlocking designs....

  19. Formal Modeling and Verification of Interlocking Systems Featuring Sequential Release

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2015-01-01

    In this paper, we present a method and an associated tool suite for formal verification of the new ETCS level 2 based Danish railway interlocking systems. We have made a generic and reconfigurable model of the system behavior and generic high-level safety properties. This model accommodates seque...... SMT based bounded model checking (BMC) and inductive reasoning, we are able to verify the properties for model instances corresponding to railway networks of industrial size. Experiments also show that BMC is efficient for finding bugs in the railway interlocking designs....

  20. A bioindicator system for water quality on inshore coral reefs of the Great Barrier Reef.

    Science.gov (United States)

    Fabricius, Katharina E; Cooper, Timothy F; Humphrey, Craig; Uthicke, Sven; De'ath, Glenn; Davidson, Johnston; LeGrand, Hélène; Thompson, Angus; Schaffelke, Britta

    2012-01-01

    Responses of bioindicator candidates for water quality were quantified in two studies on inshore coral reefs of the Great Barrier Reef (GBR). In Study 1, 33 of the 38 investigated candidate indicators (including coral physiology, benthos composition, coral recruitment, macrobioeroder densities and FORAM index) showed significant relationships with a composite index of 13 water quality variables. These relationships were confirmed in Study 2 along four other water quality gradients (turbidity and chlorophyll). Changes in water quality led to multi-faceted shifts from phototrophic to heterotrophic benthic communities, and from diverse coral dominated communities to low-diversity communities dominated by macroalgae. Turbidity was the best predictor of biota; hence turbidity measurements remain essential to directly monitor water quality on the GBR, potentially complemented by our final calibrated 12 bioindicators. In combination, this bioindicator system may be used to assess changes in water quality, especially where direct water quality data are unavailable.

  1. Mechanisms governing the interfacial delamination of thermal barrier coating system with double ceramic layers

    Science.gov (United States)

    Xu, Rong; Fan, Xueling; Wang, T. J.

    2016-05-01

    A systematic study of factors affecting the interfacial delamination of thermal barrier coating system (TBCs) with double ceramic layers (DCL) is presented. Crack driving forces for delaminations at two weak interfaces are examined. The results show that a thicker outermost ceramic layer can induce dramatic increase in crack driving force and make the interface between two ceramic coatings become more prone to delamination. The behavior is shown to be more prominent in TBCs with stiffer outmost coating. The thickness ratio of two ceramic layers is an important parameter for controlling the failure mechanisms and determining the lifetime of DCL TBCs under inservice condition. By accounting for the influences of thickness ratio of two ceramic layers and interfacial fracture toughnesses of two involved interfaces, the fracture mechanism map of DCL TBCs has been constructed, in which different failure mechanisms are identified. The results quanlitatively agree with the aviliable experimental data.

  2. Evaluation of the Lifetime and Thermal Conductivity of Dysprosia-Stabilized Thermal Barrier Coating Systems

    Science.gov (United States)

    Curry, Nicholas; Markocsan, Nicolaie; Östergren, Lars; Li, Xin-Hai; Dorfman, Mitch

    2013-08-01

    The aim of this study was the further development of dysprosia-stabilized zirconia coatings for gas turbine applications. The target for these coatings was a longer lifetime and higher insulating performance compared to today's industrial standard thermal barrier coating. Two morphologies of ceramic top coat were studied: one using a dual-layer system and the second using a polymer to generate porosity. Evaluations were carried out using a laser flash technique to measure thermal properties. Lifetime testing was conducted using thermo-cyclic fatigue testing. Microstructure was assessed with SEM and Image analysis was used to characterize porosity content. The results show that coatings with an engineered microstructure give performance twice that of the present reference coating.

  3. Reuse and recycling of secondary effluents in refineries employing advanced multi-barrier systems.

    Science.gov (United States)

    Lahnsteiner, J; Mittal, R

    2010-01-01

    In this paper the reclamation and reuse of municipal secondary effluents, as well as the reclamation and recycling of refinery secondary effluents, are technically and economically evaluated. It is shown that both practices are feasible and sustainable, and that the reclamation costs depend largely on specific circumstances such as legal requirements, price policy, reuse application, raw water composition, etc. The reclaimed water is reused, or respectively recycled, as boiler make-up. Therefore both reclamation plants employ advanced multi-barrier systems including ultra-filtration and reverse osmosis. The employed processes have shown excellent performance with regard to the removal of critical parameters such as silica. For example, this parameter was reduced from 13 mg/l in the raw water to 7 μg/l in the boiler make-up.

  4. Intelligent Learning Management Systems: Definition, Features and Measurement of Intelligence

    Science.gov (United States)

    Fardinpour, Ali; Pedram, Mir Mohsen; Burkle, Martha

    2014-01-01

    Virtual Learning Environments have been the center of attention in the last few decades and help educators tremendously with providing students with educational resources. Since artificial intelligence was used for educational proposes, learning management system developers showed much interest in making their products smarter and more…

  5. Conceptual Features of Value Management of Socio-Economic Systems

    Science.gov (United States)

    Serebryakova, Galina V.; Musayelyan, Igor K.

    2016-01-01

    The article highlights the need to establish and apply organizational and economic mechanisms that contribute to strengthening moral and ethical components in management. Emphasis is put on the issue of interactions within a company which lays a foundation for value management of socioeconomic systems. It is shown that present-day business…

  6. UAS for mapping: A product survey on systems and features

    NARCIS (Netherlands)

    Lemmens, M.J.P.M.

    2014-01-01

    In recent years, unmanned aerial systems (UAS) have attracted tremendous attention from surveyors and other geodata collectors all around the world. Nowadays, UAS equipped with GNSS, IMU and RGB, NIR or TIR cameras and possibly Lidar have evolved into high-potential surveying devices which have now

  7. Barriers to sustainable tuberculosis control in the Russian Federation health system.

    Science.gov (United States)

    Atun, R. A.; Samyshkin, Y. A.; Drobniewski, F.; Skuratova, N. M.; Gusarova, G.; Kuznetsov, S. I.; Fedorin, I. M.; Coker, R. J.

    2005-01-01

    The Russian Federation has the eleventh highest tuberculosis burden in the world in terms of the total estimated number of new cases that occur each year. In 2003, 26% of the population was covered by the internationally recommended control strategy known as directly observed treatment (DOT) compared to an overall average of 61% among the 22 countries with the highest burden of tuberculosis. The Director-General of WHO has identified two necessary starting points for the scaling-up of interventions to control emerging infectious diseases. These are a comprehensive engagement with the health system and a strengthening of the health system. The success of programmes aimed at controlling infectious diseases is often determined by constraints posed by the health system. We analyse and evaluate the impact of the arrangements for delivering tuberculosis services in the Russian Federation, drawing on detailed analyses of barriers and incentives created by the organizational structures, and financing and provider-payment systems. We demonstrate that the systems offer few incentives to improve the efficiency of services or the effectiveness of tuberculosis control. Instead, the system encourages prolonged supervision through specialized outpatient departments in hospitals (known as dispensaries), multiple admissions to hospital and lengthy hospitalization. The implementation, and expansion and sustainability of WHO-approved methods of tuberculosis control in the Russian Federation are unlikely to be realized under the prevailing system of service delivery. This is because implementation does not take into account the wider context of the health system. In order for the control programme to be sustainable, the health system will need to be changed to enable services to be reconfigured so that incentives are created to reward improvements in efficiency and outcomes. PMID:15798846

  8. Facilitators and Barriers to Safe Medication Administration to Hospital Inpatients: A Mixed Methods Study of Nurses' Medication Administration Processes and Systems (the MAPS Study.

    Directory of Open Access Journals (Sweden)

    Monsey McLeod

    Full Text Available Research has documented the problem of medication administration errors and their causes. However, little is known about how nurses administer medications safely or how existing systems facilitate or hinder medication administration; this represents a missed opportunity for implementation of practical, effective, and low-cost strategies to increase safety.To identify system factors that facilitate and/or hinder successful medication administration focused on three inter-related areas: nurse practices and workarounds, workflow, and interruptions and distractions.We used a mixed-methods ethnographic approach involving observational fieldwork, field notes, participant narratives, photographs, and spaghetti diagrams to identify system factors that facilitate and/or hinder successful medication administration in three inpatient wards, each from a different English NHS trust. We supplemented this with quantitative data on interruptions and distractions among other established medication safety measures.Overall, 43 nurses on 56 drug rounds were observed. We identified a median of 5.5 interruptions and 9.6 distractions per hour. We identified three interlinked themes that facilitated successful medication administration in some situations but which also acted as barriers in others: (1 system configurations and features, (2 behaviour types among nurses, and (3 patient interactions. Some system configurations and features acted as a physical constraint for parts of the drug round, however some system effects were partly dependent on nurses' inherent behaviour; we grouped these behaviours into 'task focused', and 'patient-interaction focused'. The former contributed to a more streamlined workflow with fewer interruptions while the latter seemed to empower patients to act as a defence barrier against medication errors by being: (1 an active resource of information, (2 a passive information resource, and/or (3 a 'double-checker'.We have identified practical

  9. An investigation of enhanced capability thermal barrier coating systems for diesel engine components

    Science.gov (United States)

    Holtzman, R. L.; Layne, J. L.; Schechter, B.

    1984-01-01

    Material systems and processes for the development of effective and durable thermal barriers for heavy duty diesel engines were investigated. Seven coating systems were evaluated for thermal conductivity, erosion resistance, corrosion/oxidation resistance, and thermal shock resistance. An advanced coating system based on plasma sprayed particle yttria stabilized zirconia (PS/HYSZ) was judged superior in these tests. The measured thermal conductivity of the selected coating was 0.893 W/m C at 371 C. The PS/HYSZ coating system was applied to the piston crown, fire deck and valves of a single cylinder low heat rejection diesel engine. The coated engine components were tested for 24 hr at power levels from 0.83 MPa to 1.17 MPa brake mean effective pressure. The component coatings survived the engine tests with a minimum of distress. The measured fire deck temperatures decreased 86 C (155 F) on the intake side and 42 C (75 F) on the exhaust side with the coating applied.

  10. Risk analysis of the governance system affecting outcomes in the Great Barrier Reef.

    Science.gov (United States)

    Dale, Allan P; Vella, Karen; Pressey, Robert L; Brodie, Jon; Gooch, Margaret; Potts, Ruth; Eberhard, Rachel

    2016-12-01

    The state and trend of the Great Barrier Reef's (GBR's) ecological health remains problematic, influencing United Nations Educational, Scientific and Cultural Organization (UNESCO) statements regarding GBR governance. While UNESCO's concerns triggered separate strategic assessments by the Australian and Queensland governments, there has been no independent and integrated review of the key risks within the overall system of governance influencing GBR outcomes. As a case study of international significance, this paper applies Governance Systems Analysis (GSA), a novel analytical framework that identifies the governance themes, domains and subdomains most likely to influence environmental and socio-economic outcomes in complex natural systems. This GBR-focussed application of GSA identifies governance subdomains that present high, medium, or low risk of failure to produce positive outcomes for the Reef. This enabled us to determine that three "whole of system" governance problems could undermine GBR outcomes. First, we stress the integrative importance of the Long Term Sustainability Plan (LTSP) Subdomain. Sponsored by the Australian and Queensland governments, this subdomain concerns the primary institutional arrangements for coordinated GBR planning and delivery, but due to its recent emergence, it faces several internal governance challenges. Second, we find a major risk of implementation failure in the achievement of GBR water quality actions due to a lack of system-wide focus on building strong and stable delivery systems at catchment scale. Finally, we conclude that the LTSP Subdomain currently has too limited a mandate/capacity to influence several high-risk subdomains that have not been, but must be more strongly aligned with Reef management (e.g. the Greenhouse Gas Emission Management Subdomain). Our analysis enables exploration of governance system reforms needed to address environmental trends in the GBR and reflects on the potential application of GSA in

  11. Discrete Solitary Waves in Systems with Nonlocal Interactions and the Peierls-Nabarro Barrier

    Science.gov (United States)

    Jenkinson, M.; Weinstein, M. I.

    2017-04-01

    We study a class of discrete focusing nonlinear Schrödinger equations (DNLS) with general nonlocal interactions. We prove the existence of onsite and offsite discrete solitary waves, which bifurcate from the trivial solution at the endpoint frequency of the continuous spectrum of linear dispersive waves. We also prove exponential smallness, in the frequency-distance to the bifurcation point, of the Peierls-Nabarro energy barrier (PNB), as measured by the difference in Hamiltonian or mass functionals evaluated on the onsite and offsite states. These results extend those of the authors for the case of nearest neighbor interactions to a large class of nonlocal short-range and long-range interactions. The appearance of distinct onsite and offsite states is a consequence of the breaking of continuous spatial translation invariance. The PNB plays a role in the dynamics of energy transport in such nonlinear Hamiltonian lattice systems. Our class of nonlocal interactions is defined in terms of coupling coefficients, J m , where {min{Z}} is the lattice site index, with {J_m˜eq m^{-1-2s}, sin[1,∞)} and {J_m˜ e^{-γ|m|}, s=∞, γ > 0,} (Kac-Baker). For {s≥1}, the bifurcation is seeded by solutions of the (effective/homogenized) cubic focusing nonlinear Schrödinger equation (NLS). However, for {1/4 equation, FNLS, with {(-Δ)^s} replacing {-Δ}. The proof is based on a Lyapunov-Schmidt reduction strategy applied to a momentum space formulation. The PN barrier bounds require appropriate uniform decay estimates for the discrete Fourier transform of DNLS discrete solitary waves. A key role is also played by non-degeneracy of the ground state of FNLS, recently proved by Frank, Lenzmann and Silvestrie.

  12. Pathways and hydrography in the Mesoamerican Barrier Reef System Part 2: Water masses and thermohaline structure

    Science.gov (United States)

    Carrillo, L.; Johns, E. M.; Smith, R. H.; Lamkin, J. T.; Largier, J. L.

    2016-06-01

    Hydrographic data from two oceanographic cruises conducted during March 2006 and January/February 2007 are used to investigate the thermohaline structure related to the observed circulation along the Mesoamerican Barrier Reef System (MBRS). From our observations we identify three water masses in the MBRS: the Caribbean Surface Water (CSW), North Atlantic Subtropical Underwater (SUW), and Tropical Atlantic Central Water (TACW). Little vertical structure in temperature is observed in the upper 100 m of the water column, but important differences are observed in the salinity distribution both horizontally and with depth. Freshwater inputs to the system from the mainland can be traced in the surface layer, with two possible sources: one from surface rivers located along the southern portion of the MBRS, and the other originating from an underground river system located along the northern portion of the MBRS. The thermohaline structure in the MBRS reflects the dynamics of the observed circulation. Uplifted isopycnals along most of the central and northern coastline of the MBRS reflect the effects of the strong geostrophic circulation flowing northward, i.e. the Yucatan Current. To the south along the MBRS, much weaker velocities are observed, with the Honduras Gyre dominating the flow in this region as presented during January/February 2007. These two regions are separated by onshore and divergent alongshore flow associated with the impingement of the Cayman Current on the shore and the MBRS.

  13. A method for risk analysis across governance systems: a Great Barrier Reef case study

    Science.gov (United States)

    Dale, Allan; Vella, Karen; Pressey, Robert L.; Brodie, Jon; Yorkston, Hugh; Potts, Ruth

    2013-03-01

    Healthy governance systems are key to delivering sound environmental management outcomes from global to local scales. There are, however, surprisingly few risk assessment methods that can pinpoint those domains and sub-domains within governance systems that are most likely to influence good environmental outcomes at any particular scale, or those if absent or dysfunctional, most likely to prevent effective environmental management. This paper proposes a new risk assessment method for analysing governance systems. This method is then tested through its preliminary application to a significant real-world context: governance as it relates to the health of Australia’s Great Barrier Reef (GBR). The GBR exists at a supra-regional scale along most of the north eastern coast of Australia. Brodie et al (2012 Mar. Pollut. Bull. 65 81-100) have recently reviewed the state and trend of the health of the GBR, finding that overall trends remain of significant concern. At the same time, official international concern over the governance of the reef has recently been signalled globally by the International Union for the Conservation of Nature (IUCN). These environmental and political contexts make the GBR an ideal candidate for use in testing and reviewing the application of improved tools for governance risk assessment.

  14. Examining Barriers to Internationalisation Created by Diverse Systems and Structures in Vocational Education and Training

    Directory of Open Access Journals (Sweden)

    Angela Joy Shaw

    2016-08-01

    Full Text Available In a global society, all educational sectors need to recognise internationalism as a core, foundational principle. Whilst most educational sectors are taking up that challenge, vocational education and training (VET is still being pulled towards the national agenda in terms of its structures and systems, and the policies driving it, disadvantaging those who graduate from VET, those who teach in it, and the businesses and countries that connect with it. This paper poses questions about the future of internationalisation in the sector. It examines whether there is a way to create a VET system that meets its primary point of value, to produce skilled workers for the local labour market, while still benefitting those graduates by providing international skills and knowledge, gained from VET institutions that are international in their outlook. The paper examines some of the key barriers created by systems and structures in VET to internationalisation and suggests that the efforts which have been made to address the problem have had limited success. It suggests that only a model which gives freedom to those with a direct vested interest, students, teachers, trainers and employers, to pursue international co-operation and liaison will have the opportunity to succeed.

  15. Residual stress analysis of the thermal barrier coating system by considering the plasma spraying process

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myung Jae; Lee, Byung Chai [KAIST, Daejeon (Korea, Republic of); Lim, Jang Gyun; Kim, Moon Ki [Sungkyunkwan University, Suwon (Korea, Republic of)

    2014-06-15

    The residual stress is the key factor causing the reliability problem of thermal barrier coating (TBC). The failure of plasma spray coatings due to residual stresses is a serious and recurring problem of TBC. The difference of thermal expansion coefficient between the substrate and each coating combined with temperature evolution and temperature gradients during deposition process determine the residual stress for the whole TBC system. The magnitudes and distributions of the residual stresses are affected by deposition process and deposition characteristics. Most of FEA (finite element analysis) has been performed under the assumption that the multilayer coating system is stacked at once without considering the deposition process during plasma spraying. In this research, FEA for a coupled heat transfer and elastic-plastic thermal stress was performed to obtain the more detailed and reliable result of residual stress of the TBC system using the element activation/deactivation technique. The residual stress variation from the start of plasma spraying to cooling stage with room temperature was obtained systematically considering the deposition process. It can be used as reference data to improve the performance of TBC. In addition, the relationship between residual stress and coating conditions such as cooling rate and time is also examined thoroughly.

  16. Robot Vision System for Coordinate Measurement of Feature Points on Large Scale Automobile Part

    Institute of Scientific and Technical Information of China (English)

    Pongsak Joompolpong; Pradit Mittrapiyanuruk; Pakorn Keawtrakulpong

    2016-01-01

    In this paper, we present a robot vision based system for coordinate measurement of feature points on large scale automobile parts. Our system consists of an industrial 6-DOF robot mounted with a CCD camera and a PC. The system controls the robot into the area of feature points. The images of measuring feature points are acquired by the camera mounted on the robot. 3D positions of the feature points are obtained from a model based pose estimation that applies to the images. The measured positions of all feature points are then transformed to the reference coordinate of feature points whose positions are obtained from the coordinate measuring machine (CMM). Finally, the point-to-point distances between the measured feature points and the reference feature points are calculated and reported. The results show that the root mean square error (RMSE) of measure values obtained by our system is less than 0.5mm. Our system is adequate for automobile assembly and can perform faster than conventional methods.

  17. Motivators, Barriers and Concerns in Adoption of Electronic Filing System: Survey Evidence from Malaysian Professional Accountants

    Directory of Open Access Journals (Sweden)

    Ming-Ling Lai

    2010-01-01

    Full Text Available Problem statement: Worldwide, electronic filing (e-filing system and its' adoption has attracted much attention, however, scholarly study on accounting professionals' acceptance of e-filing system is scant. Approach: This study aimed (i to examine factors that motivated professional accountants to use e-filing (ii to solicit their usage experience and (iii to assess the barriers to adoption and other compliance considerations. The questionnaire survey was administered on 700 professionals from tax practice and commercial sectors who attended "Budget 2008" Tax Seminars, organized by the Malaysian Institute of Accountants in Peninsular Malaysia. In total, 456 usable responses from accounting and tax professionals were collected and analyzed. Results: The survey found out of 456 respondents, just 23.7% had used e-filing in 2007 to file personal tax return forms. Majority of the e-filers opted to use e-filing for the sake of convenience (55.8%, in faith to get faster tax refund (16.8% and speed of filing (15.9%. For those who did not use e-filing, the key impediments were concerned over the security and did not trust of e-filing system. Some (4.8% were unable to access to the e-filing website. Overall, just 26.1% of the professionals surveyed had confidence in the IRBM in managing the e-filing system successfully. Majority (41.2% thought that 'speedy tax refund' to be the most desirable incentive to motivate individuals to use e-filing. Conclusion: As the IRBM is counting on professional accountants to promote the usage of e-filing system, this study provided important insights to the IRBM to developing marketing and business strategies to motivate professional accountant in business to use e-filing in order to accelerate the diffusion of e-filing system in a developing country like Malaysia.

  18. Color and Texture Feature for Remote Sensing - Image Retrieval System: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Retno Kusumaningrum

    2011-09-01

    Full Text Available In this study, we proposed score fusion technique to improve the performance of remote sensing image retrieval system (RS-IRS using combination of several features. The representation of each feature is selected based on their performance when used as single feature in RS-IRS. Those features are color moment using L*a*b* color space, edge direction histogram extracted from Saturation channel, GLCM and Gabor Wavelet represented using standard deviation, and local binary pattern using 8-neighborhood. The score fusion is performed by computing the value of image similarity between an image in the database and query, where the image similarity value is sum of all features similarity, where each of feature similarity has been divided by SVD value of feature similarity between all images in the database and query from related feature. The feature similarity is measured by histogram intersection for local binary pattern, whereas the color moment, edge direction histogram, GLCM, and Gabor are measured by Euclidean Distance. The final result shows that the best performance of remote sensing image retrieval in this study is a system which uses the combination of color and texture features (i.e. color moment, edge direction histogram, GLCM, Gabor wavelet, and local binary pattern and uses score fusion in measuring the image similarity between query and images in the database. This system outperforms the other five individual feature with average precision rates 3%, 20%, 13%, 11%, and 9%, respectively, for color moment, edge direction histogram, GLCM, Gabor wavelet, and LBP. Moreover, this system also increase 17% compared to system without score fusion, simple-sum technique.

  19. Barriers to Health Promotion and Disease Prevention Within the Military Healthcare System

    Science.gov (United States)

    2013-01-31

    1997). Barriers encountered in osteoporosis prevention are related to the fear that estrogen therapy is harmful (Salamone, Barriers to Health...immunization, mammography, cervical Papanicolaou smear, and physical examination (Dutton, 1986; Elnicki, Morris, & Shockcor, 1995). Provider-Consumer...waiting times at appointments, lack of evening and weekend appointments, inadequate physical space, and inadequate facilities for child care also

  20. Satisficing-Based Approach to Resolve Feature Interactions in Control Systems

    DEFF Research Database (Denmark)

    Sørensen, Jan Corfixen; Jørgensen, Bo Nørregaard

    2013-01-01

    problem. We demonstrate our approach in a real-life control system for industrial pot plant cultivation in greenhouses and show that solutions are found for compatible requirements and that conflicts are identified and explained for incompatible requirements. © 2013 Springer Science+Business Media.......To handle the complexity of modern control systems there is an urgent need to develop features as independently developed units of extension. However, when independently developed features are later composed they become coupled through the shared environment resources. As a consequence, the system...... requirements may no longer be entailed when independent features try to control the same shared environment. Malfunctioning behavior as a consequence of feature interference is know in the literature as the feature interaction problem. This paper present an approach that uses designtime specification...

  1. The socio-technical barriers to Solar Home Systems (SHS) in Papua New Guinea: 'Choosing pigs, prostitutes, and poker chips over panels'

    Energy Technology Data Exchange (ETDEWEB)

    Sovacool, Benjamin K., E-mail: bsovacool@nus.edu.s [Lee Kuan Yew School of Public Policy, National University of Singapore, 469C Bukit Timah Road, Singapore 259772 (Singapore); D' Agostino, Anthony L.; Jain Bambawale, Malavika [Lee Kuan Yew School of Public Policy, National University of Singapore, 469C Bukit Timah Road, Singapore 259772 (Singapore)

    2011-03-15

    This study explores the socio-technical barriers to Solar Home Systems (SHS) in Papua New Guinea. The authors collected primary data through semi-structured research interviews conducted over the course of February 2010-April 2010. Respondents included government officials, financiers, planners, commercial distributors and companies, teachers and rural villagers in addition to members of civil society, academics, consultants, and trainers. These interviews were supplemented with site visits to Port Moresby, Goroka, and Madang, and field research in the villages of Akameku, Asaroka, Lufa, Kundiawa, Okifa, Simbu, and Talidig. The study draws from these interviews and visits to discuss four types of barriers. Technical barriers relate to substandard equipment and logistical problems. Economic barriers include high rates of poverty, misconceptions about the role of currency, and lack of financing. Political barriers include poor institutional capacity and a government commitment to fossil-fueled grid electrification. Social barriers encompass unrealistic expectations about what SHS can provide along with jealousy, theft, vandalism, and unfamiliarity with solar technology. - Research highlights: {yields} Solar Home Systems (SHS) are impeded by a collection of different barriers in Papua New Guinea. {yields} Technical barriers relate to substandard equipment and logistical problems. {yields} Economic barriers include high rates of poverty, misconceptions about the role of currency, and lack of financing.{yields} Political barriers include poor institutional capacity and a government commitment to fossil-fueled grid electrification. {yields} Social barriers encompass unrealistic expectations about what SHS can provide along with jealousy, theft, vandalism, and unfamiliarity with solar technology.

  2. Wheelchair users’ perspectives on barriers in public spaces in Vienna: implications for the development of a barrier information system / Barrieren aus der Sicht von Rollstuhlnutzern/-innen im öffentlichen Raum in Wien: Implikationen für ein Barriere-Informationssystem

    Directory of Open Access Journals (Sweden)

    Außermaier Hannes

    2016-12-01

    Full Text Available Wheelchair users often encounter barriers reducing community mobility and participation in societal life. Information on barrier-free routes may improve mobility and therefore societal participation. In addition to technical prerequisites, a routing system will only be effective and used by the target group, if the development process is based on their perceptions and needs. The aim of the study was therefore to collect data on barriers from the viewpoint of wheelchair users in Vienna.

  3. AVNG SYSTEM SOFTWARE - ATTRIBUTE VERIFICATION SYSTEM WITH INFORMATION BARRIERS FOR MASS AND ISOTOPICS MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Modenov, A; Bulatov, M; Livke, A; Morkin, A; Razinkov, S; Safronov, S; Elmont, T; Langner, D; MacArthur, D; Mayo, D; Smith, M; Luke, S J

    2005-06-10

    This report describes the software development for the plutonium attribute verification system--AVNG. A brief synopsis of the technical solution for the measurement system is presented. The main tasks for the software development that is underway are formulated. The development tasks are shown in software structural flowcharts, measurement system state diagram and a description of the software. The current status of the AVNG software development is elucidated.

  4. Implementation of multiple-domain covering computerized decision support systems in primary care: a focus group study on perceived barriers

    NARCIS (Netherlands)

    Lugtenberg, M.; Weenink, J.W.; Weijden, T. van der; Westert, G.P.; Kool, R.B.

    2015-01-01

    BACKGROUND: Despite the widespread availability of computerized decision support systems (CDSSs) in various healthcare settings, evidence on their uptake and effectiveness is still limited. Most barrier studies focus on CDSSs that are aimed at a limited number of decision points within selected smal

  5. Implementation of multiple-domain covering computerized decision support systems in primary care : A focus group study on perceived barriers

    NARCIS (Netherlands)

    Lugtenberg, M.; Weenink, Jan-Willem; van der Weijden, Trudy; Westert, G.P.; Kool, Rudolf B.

    2015-01-01

    Background Despite the widespread availability of computerized decision support systems (CDSSs) in various healthcare settings, evidence on their uptake and effectiveness is still limited. Most barrier studies focus on CDSSs that are aimed at a limited number of decision points within selected small

  6. Study of nuclear structure effect on fusion through barrier distribution for the system 28Si+154Sm

    Directory of Open Access Journals (Sweden)

    Kaur Gurpreet

    2015-01-01

    Full Text Available We plan to perform large angle quasi-elastic scattering experiments using a 28Si beam on heavy targets in order to study the nuclear dynamics and structure effects. As a prelude to our first test experiment with a 154Sm target, we study here the existing fusion data for the same system through the barrier distribution.

  7. Review of underground logistic systems in the Netherlands: an ex-post evaluation of barriers, enablers and spin-offs

    NARCIS (Netherlands)

    Wiegmans, B.W.; Visser, J.; Konings, R.; Pielage, B.J.A.

    2010-01-01

    Now, 10 years after the first plans, we analyse in this paper what has happened with Underground Logistic Systems (ULS). The major question in this paper is: Which barriers and enablers led to the failure of ULS and what ULS spin-offs can be found nowadays? Several factors can be classified as barri

  8. A HYBRID APPROACH BASED MEDICAL IMAGE RETRIEVAL SYSTEM USING FEATURE OPTIMIZED CLASSIFICATION SIMILARITY FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Yogapriya Jaganathan

    2013-01-01

    Full Text Available For the past few years, massive upgradation is obtained in the pasture of Content Based Medical Image Retrieval (CBMIR for effective utilization of medical images based on visual feature analysis for the purpose of diagnosis and educational research. The existing medical image retrieval systems are still not optimal to solve the feature dimensionality reduction problem which increases the computational complexity and decreases the speed of a retrieval process. The proposed CBMIR is used a hybrid approach based on Feature Extraction, Optimization of Feature Vectors, Classification of Features and Similarity Measurements. This type of CBMIR is called Feature Optimized Classification Similarity (FOCS framework. The selected features are Textures using Gray level Co-occurrence Matrix Features (GLCM and Tamura Features (TF in which extracted features are formed as feature vector database. The Fuzzy based Particle Swarm Optimization (FPSO technique is used to reduce the feature vector dimensionality and classification is performed using Fuzzy based Relevance Vector Machine (FRVM to form groups of relevant image features that provide a natural way to classify dimensionally reduced feature vectors of images. The Euclidean Distance (ED is used as similarity measurement to measure the significance between the query image and the target images. This FOCS approach can get the query from the user and has retrieved the needed images from the databases. The retrieval algorithm performances are estimated in terms of precision and recall. This FOCS framework comprises several benefits when compared to existing CBMIR. GLCM and TF are used to extract texture features and form a feature vector database. Fuzzy-PSO is used to reduce the feature vector dimensionality issues while selecting the important features in the feature vector database in which computational complexity is decreased. Fuzzy based RVM is used for feature classification in which it increases the

  9. Solving problems in social-ecological systems: definition, practice and barriers of transdisciplinary research.

    Science.gov (United States)

    Angelstam, Per; Andersson, Kjell; Annerstedt, Matilda; Axelsson, Robert; Elbakidze, Marine; Garrido, Pablo; Grahn, Patrik; Jönsson, K Ingemar; Pedersen, Simen; Schlyter, Peter; Skärbäck, Erik; Smith, Mike; Stjernquist, Ingrid

    2013-03-01

    Translating policies about sustainable development as a social process and sustainability outcomes into the real world of social-ecological systems involves several challenges. Hence, research policies advocate improved innovative problem-solving capacity. One approach is transdisciplinary research that integrates research disciplines, as well as researchers and practitioners. Drawing upon 14 experiences of problem-solving, we used group modeling to map perceived barriers and bridges for researchers' and practitioners' joint knowledge production and learning towards transdisciplinary research. The analysis indicated that the transdisciplinary research process is influenced by (1) the amount of traditional disciplinary formal and informal control, (2) adaptation of project applications to fill the transdisciplinary research agenda, (3) stakeholder participation, and (4) functional team building/development based on self-reflection and experienced leadership. Focusing on implementation of green infrastructure policy as a common denominator for the delivery of ecosystem services and human well-being, we discuss how to diagnose social-ecological systems, and use knowledge production and collaborative learning as treatments.

  10. Spatiotemporal variability of sedimentology and morphology in the East Frisian barrier island system

    Science.gov (United States)

    Herrling, Gerald; Winter, Christian

    2016-08-01

    The highly dynamic East Frisian barrier island system (southern North Sea) is characterized by a complex morphology of tidal inlets, ebb-tidal deltas and foreshore beaches that reacts to storms and fair-weather conditions with characteristic patterns of sediment grain-size distributions. The morphological and sedimentological response to varying hydrodynamic conditions yet occurs in short time spans that are not covered by common monitoring strategies with measuring intervals typically of years. This study applies process-based numerical modelling with multiple sediment fractions to interpolate morphological states in time between bathymetrical surveys conducted in the summer months of 2004 and 2006. Morphodynamic simulations driven by real-time boundary conditions of tides, wind and waves are carried out for a representative period of 2 years. The spatiotemporal variability of the nearshore sedimentology and morphology is assessed by graded ranges of bed dynamics (i.e. bed elevation range) and the definition of sediment grain-size variability (i.e. mean diameter range). The effect of storm events and timescales of the sedimentological adaptation after storms to typical fair-weather conditions are exemplified at an ebb-tidal delta lobe where the morphological and sedimentological variability is found to be largest in the study area. The proposed method may serve to identify areas of high sedimentological and morphological activity for system understanding or in the framework of coastal monitoring strategies.

  11. Novel targeted approach to better understand how natural structural barriers govern carotenoid in vitro bioaccessibility in vegetable-based systems.

    Science.gov (United States)

    Palmero, Paola; Lemmens, Lien; Ribas-Agustí, Albert; Sosa, Carola; Met, Kristof; de Dieu Umutoni, Jean; Hendrickx, Marc; Van Loey, Ann

    2013-12-01

    An experimental approach, allowing us to understand the effect of natural structural barriers (cell walls, chromoplast substructures) on carotenoid bioaccessibility, was developed. Different fractions with different levels of carotenoid bio-encapsulation (carotenoid-enriched oil, chromoplasts, small cell clusters, and large cell clusters) were isolated from different types of carrots and tomatoes. An in vitro method was used to determine carotenoid bioaccessibility. In the present work, a significant decrease in carotenoid in vitro bioaccessibility could be observed with an increasing level of bio-encapsulation. Differences in cell wall material and chromoplast substructure between matrices influenced carotenoid release and inclusion in micelles. For carrots, cell walls and chromoplast substructure were important barriers for carotenoid bioaccessibility while, in tomatoes, the chromoplast substructure represented the most important barrier governing bioaccessibility. The highest increase in carotenoid bioaccessibility, for all matrices, was obtained after transferring carotenoids into the oil phase, a system lacking cell walls and chromoplast substructures that could hamper carotenoid release.

  12. Converse Barrier Certificate Theorems

    DEFF Research Database (Denmark)

    Wisniewski, Rafael; Sloth, Christoffer

    2016-01-01

    This paper shows that a barrier certificate exists for any safe dynamical system. Specifically, we prove converse barrier certificate theorems for a class of structurally stable dynamical systems. Other authors have developed a related result by assuming that the dynamical system has neither sing...

  13. Durability and CMAS Resistance of Advanced Environmental Barrier Coatings Systems for SiC/SiC Ceramic Matrix Composites

    Science.gov (United States)

    Zhu, Dongming

    2015-01-01

    Environmental barrier coatings (EBCs) and SiCSiC ceramic matrix composites (CMCs) systems will play a crucial role in next generation turbine engines for hot-section component applications because of their ability to significantly increase engine operating temperatures with improved efficiency, reduce engine weight and cooling requirements. This paper will emphasize advanced environmental barrier coating developments for SiCSiC turbine airfoil components, by using advanced coating compositions and processing, in conjunction with mechanical and environment testing and durability validations. The coating-CMC degradations and durability in the laboratory simulated engine fatigue-creep and complex operating environments are being addressed. The effects of Calcium-Magnesium-Alumino-Silicate (CMAS) from road sand or volcano-ash deposits on the degradation mechanisms of the environmental barrier coating systems will be discussed. The results help understand the advanced EBC-CMC system performance, aiming at the durability improvements of more robust, prime-reliant environmental barrier coatings for successful applications of the component technologies and lifing methodologies.

  14. Modeling Training of Future Teachers Aimed on Innovation Activities Based on the System of Design Features

    Directory of Open Access Journals (Sweden)

    Yury S. Tyunnikov

    2015-05-01

    Full Text Available Modeling of training system of future teachers aimed on innovation activities performed in a certain project logic and procedures, which is possible only through a specific set of design features, based on capability and peculiar properties of the university. The article is formulated and solved the problem of design features, revealing in its set the characteristic properties, organization and functioning of training system aimed on innovation in specific terms of professional education.

  15. CONTROL SYSTEM FEATURES OF MAGNETIC-PULSE INSTALLATION AT UNIPOLAR MODE

    Directory of Open Access Journals (Sweden)

    Dzyubenko, A.

    2012-06-01

    Full Text Available Construction features of monitoring and control system of magnetic pulse installation at work in unipolar mode were detected. Installation control system algorithm at work in multiple repeating mode of discharge pulses is proposed. Description of monitoring and control system structure schemes and their purposes have been conducted.

  16. Changes in skin barrier during treatment with systemic alitretinoin: focus on skin susceptibility and stratum corneum ceramides.

    Science.gov (United States)

    Jungersted, Jakob Mutanu; Høgh, Julie K; Hellgren, Lars I; Jemec, Gregor B E; Agner, Tove

    2010-11-01

    Alitretinoin is a new drug for systemic treatment of chronic hand eczema. Previous functional tests of skin topically treated with retinoids have indicated impaired skin barrier function, but no data are available on barrier parameters after systemic alitretinoin treatment. To investigate the effect of systemic alitretinoin on skin barrier function and response to irritants, a secondary objective was to determine if changes occur in the lipid profile of stratum corneum after treatment with systemic alitretinoin. We conducted an open clinical intervention study on eight people ascribed to systemic alitretinoin treatment. The criteria for being ascribed to alitretinoin were chronic hand eczema and insufficient therapeutic response to potent topical corticosteroids. Before initiation and after 2 months of systemic treatment with 30 mg alitretinoin, a challenge with sodium lauryl sulphate (SLS) was performed on the volar forearm and evaluated by trans-epidermal water loss (TEWL), erythema, and a cyanoacrylate skin sample was obtained for lipid analysis. We found no significant changes in response to SLS irritation as evaluated by TEWL and erythema, after treatment with alitretinoin for 2 months. No significant changes in stratum corneum lipids were found after 2 months of treatment. In conclusion, systemic alitretinoin does not influence skin susceptibility to irritants or the ceramide profile of stratum corneum.

  17. DETERMINATION OF CREEP PROPERTIES OF THERMAL BARRIER COATING(TBC) SYSTEMS FROM THE INDENTATION CREEP TESTING WITH ROUND FLAT INDENTERS

    Institute of Scientific and Technical Information of China (English)

    B. Zhao; B.X. Xu; J. Liu; Z.F. Yue

    2004-01-01

    Indentation creep behavior with cylindrical flat indenters on the thermal barrier coating (TBC) was studied by finite element method (FEM). On the constant applied indentation creep stress, there is a steady creep rate for each case studied for different creep properties of the TBC system. The steady creep depth rate depends on the applied indentation creep stress and size of the indenters as well as the creep properties of the bond coat of the TBC and the substrate. The possibilities to determine the creep properties of a thermal barrier system from indention creep testing were discussed. As an example, with two different size indenters, the creep properties of bond coat of the TBC system can be derived by an inverse FEM method. This study not only provides a numerical method to obtain the creep properties of the TBC system, but also extends the application of indentation creep method with cylindrical flat indenters.

  18. Nanowired Drug Delivery Across the Blood-Brain Barrier in Central Nervous System Injury and Repair.

    Science.gov (United States)

    Sharma, Aruna; Menon, Preeti; Muresanu, Dafin F; Ozkizilcik, Asya; Tian, Z Ryan; Lafuente, José V; Sharma, Hari S

    2016-01-01

    The blood-brain barrier (BBB) is a physiological regulator of transport of essential items from blood to brain for the maintenance of homeostasis of the central nervous system (CNS) within narrow limits. The BBB is also responsible for export of harmful or metabolic products from brain to blood to keep the CNS fluid microenvironment healthy. However, noxious insults to the brain caused by trauma, ischemia or environmental/chemical toxins alter the BBB function to small as well as large molecules e.g., proteins. When proteins enter the CNS fluid microenvironment, development of brain edema occurs due to altered osmotic balance between blood and brain. On the other hand, almost all neurodegenerative diseases and traumatic insults to the CNS and subsequent BBB dysfunction lead to edema formation and cell injury. To treat these brain disorders suitable drug therapy reaching their brain targets is needed. However, due to edema formation or only a focal disruption of the BBB e.g., around brain tumors, many drugs are unable to reach their CNS targets in sufficient quantity. This results in poor therapeutic outcome. Thus, new technology such as nanodelivery is needed for drugs to reach their CNS targets and be effective. In this review, use of nanowires as a possible novel tool to enhance drug delivery into the CNS in various disease models is discussed based on our investigations. These data show that nanowired delivery of drugs may have superior neuroprotective ability to treat several CNS diseases effectively indicating their role in future therapeutic strategies.

  19. International Collaborations on Engineered Barrier Systems: Brief Overview of SKB-EBS Activities.

    Energy Technology Data Exchange (ETDEWEB)

    Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    Research collaborations with international partners on the behavior and performance of engineered barrier systems (EBS) are an important aspect of the DOE-NE Used Fuel Disposition Campaign strategy in the evaluation of disposal design concepts. These international partnerships are a cost-effective way of engaging in key R&D activities with common goals resulting in effective scientific knowledge exchanges thus enhancing existing and future research programs in the USA. This report provides a brief description of the activities covered by the Swedish Nuclear Fuel and Waste Management Company (SKB) EBS Task Force (TF) (referred hereafter as SKB EBS TF) and potential future directions for engagement of the DOE-NE UFDC program in relevant R&D activities. Emphasis is given to SKB EBS TF activities that are still ongoing and aligned to the UFDC R&D program. This include utilization of data collected in the bentonite rock interaction experiment (BRIE) and data sets from benchmark experiments produced by the chemistry or “C” part of the SKB EBS TF. Potential applications of information generated by this program include comparisons/tests between model and data (e.g., reactive diffusion), development and implementation of coupled-process models (e.g., HM), and code/model benchmarking.

  20. Numerical study of a simple transcranial focused ultrasound system applied to blood-brain barrier opening.

    Science.gov (United States)

    Deffieux, Thomas; Konofagou, Elisa E

    2010-12-01

    In this paper, we investigate the focalization properties of single-element transducers at low frequencies (300 to 1000 kHz) through primate and human skulls. The study addresses the transcranial targeting involved in ultrasound- induced blood-brain barrier (BBB) opening with clinically relevant targets such as the hippocampus and the basal ganglia, which are typically affected by early Alzheimer's and Parkinson's disease, respectively. A finite-difference, timedomain simulation platform is used to solve the 3-D linear acoustic wave equation with CT-based acoustic maps of the skulls. The targeted brain structures were extracted from 3-D brain atlases registered with the skulls and used to virtually position and orient the transducers. The effect of frequency is first investigated and the targeting of the different structures is then tested. The frequency of 500 kHz provided the best tradeoff between phase aberrations and standing wave effects in the human case, whereas the frequency of 800 kHz was most suitable in the case of the primate skull. A fast periodic linear chirp method was developed and found capable of reducing the standing wave effects. Such a simple, affordable, and convenient system is concluded to be feasible for BBB opening in primates and humans and could thus allow for its broader impact and applications.

  1. The density-driven circulation of the coastal hypersaline system of the Great Barrier Reef, Australia.

    Science.gov (United States)

    Salamena, Gerry G; Martins, Flávio; Ridd, Peter V

    2016-04-15

    The coastal hypersaline system of the Great Barrier Reef (GBR) in the dry season, was investigated for the first time using a 3D baroclinic model. In the shallow coastal embayments, salinity increases to c.a. 1‰ above typical offshore salinity (~35.4‰). This salinity increase is due to high evaporation rates and negligible freshwater input. The hypersalinity drifts longshore north-westward due to south-easterly trade winds and may eventually pass capes or headlands, e.g. Cape Cleveland, where the water is considerably deeper (c.a. 15m). Here, a pronounced thermohaline circulation is predicted to occur which flushes the hypersalinity offshore at velocities of up to 0.08m/s. Flushing time of the coastal embayments is around 2-3weeks. During the dry season early summer, the thermohaline circulation reduces and therefore, flushing times are predicted to be slight longer due to the reduced onshore-offshore density gradient compared to that in the dry season winter period.

  2. Addressing health system barriers to access to and use of skilled delivery services: perspectives from Ghana.

    Science.gov (United States)

    Ganle, John Kuumuori; Fitzpatrick, Raymond; Otupiri, Easmon; Parker, Michael

    2016-10-01

    Poor access to and use of skilled delivery services have been identified as a major contributory factor to poor maternal and newborn health in sub-Saharan African countries, including Ghana. However, many previous studies that examine norms of childbirth and care-seeking behaviours have focused on identifying the norms of non-use of services, rather than factors, that can promote service use. Based on primary qualitative research with a total of 185 expectant and lactating mothers, and 20 healthcare providers in six communities in Ghana, this paper reports on strategies that can be used to overcome health system barriers to the use of skilled delivery services. The strategies identified include expansion and redistribution of existing maternal health resources and infrastructure, training of more skilled maternity caregivers, instituting special programmes to target women most in need, improving the quality of maternity care services provided, improving doctor-patient relationships in maternity wards, promotion of choice, protecting privacy and patient dignity in maternity wards and building partnerships with traditional birth attendants and other non-state actors. The findings suggest the need for structural changes to maternity clinics and routine nursing practices, including an emphasis on those doctor-patient relational practices that positively influence women's healthcare-seeking behaviours. Copyright © 2015 John Wiley & Sons, Ltd.

  3. Mini-med school for Aboriginal youth: experiential science outreach to tackle systemic barriers

    Directory of Open Access Journals (Sweden)

    Rita I. Henderson

    2015-12-01

    Full Text Available Introduction: Addressing systemic barriers experienced by low-income and minority students to accessing medical school, the University of Calgary's Cumming School of Medicine has spearheaded a year-round, mini-med school outreach initiative for Aboriginal students. Method: Junior and senior high school youth generally attend the half-day program in classes or camps of 15–25, breaking into small groups for multisession activities. Undergraduate medical education students mentor the youth in stations offering experiential lessons in physical examination, reading x-rays, and anatomy. All resources from the medical school are offered in-kind, including a pizza lunch at midday, whereas community partners organize transportation for the attendees. Results: Opening the medical school and its resources to the community offers great benefits to resource-constrained schools often limited in terms of science education resources. The model is also an effort to address challenges among the medical professions around attracting and retaining students from underserved populations. Conclusion: The prospect of increasing admission rates and successful completion of medical education among students from marginalized communities poses a real, though difficult-to-measure, possibility of increasing the workforce most likely to return to and work in such challenging contexts. A mini-medical school for Aboriginal youth highlights mutual, long-term benefit for diverse partners, encouraging medical educators and community-based science educators to explore the possibilities for deepening partnerships in their own regions.

  4. Simulation of residual stresses and their effects on thermal barrier coating systems using finite element method

    Science.gov (United States)

    Zhu, JianGuo; Chen, Wei; Xie, HuiMin

    2015-03-01

    Thermal barrier coating (TBC) systems are widely used in industrial gas-turbine engines. However, premature failures have impaired the use of TBCs and cut down their lifetime, which requires a better understanding of their failure mechanisms. In the present study, experimental studies of isothermal cycling are firstly carried out with the observation and estimation of microstructures. According to the experimental results, a finite element model is established for the analysis of stress perpendicular to the TBC/BC interface. Detailed residual stress distributions in TBC are obtained to reflect the influence of mechanical properties, oxidation, and interfacial roughness. The calculated results show that the maximum tensile stress concentration appears at the peak of TBC and continues to increase with thermal cycles. Because of the microstructural characteristics of plasma-sprayed TBCs, cracks initialize in tensile stress concentration (TSC) regions at the peaks of TBC and propagate along the TBC/BC interface resulting in the spallation of TBC. Also, the inclusion of creep is crucial to failure prediction and is more important than the inclusion of sintering in the simulation.

  5. Improving energy efficiency in industrial energy systems an interdisciplinary perspective on barriers, energy audits, energy management, policies, and programs

    CERN Document Server

    Thollander, Patrik

    2012-01-01

    Industrial energy efficiency is one of the most important means of reducing the threat of increased global warming. Research however states that despite the existence of numerous technical energy efficiency measures, its deployment is hindered by the existence of various barriers to energy efficiency. The complexity of increasing energy efficiency in manufacturing industry calls for an interdisciplinary approach to the issue. Improving energy efficiency in industrial energy systems applies an interdisciplinary perspective in examining energy efficiency in industrial energy systems, and discuss

  6. Improving the precision of CBIR systems by color and texture feature adaptation using GSA

    Directory of Open Access Journals (Sweden)

    E. Rashedi

    2013-12-01

    Full Text Available Content-based image retrieval, CBIR, is an interesting problem of pattern recognition. This paper is devoted to the presentation an approach to reduce the semantic gap between low level visual features and high level semantics by parameter adaptation in feature extraction sub-block. In the proposed method, GSA is used. In texture feature extraction, the parameters of a 6-tap parametrized orthogonal mother wavelet and in color feature extraction, the quantization levels are adapted to reach maximum precision of the image retrieval system. Experimental results and comparison with the conventional CBIR system are reported on a database of 1000 images. Results confirm the efficiency of the proposed adapted image retrieval system.

  7. Political, policy and social barriers to health system interoperability: emerging opportunities of Web 2.0 and 3.0.

    Science.gov (United States)

    Juzwishin, Donald W M

    2009-01-01

    Achieving effective health informatics interoperability in a fragmented and uncoordinated health system is by definition not possible. Interoperability requires the simultaneous integration of health care processes and information across different types and levels of care (systems thinking). The fundamental argument of this paper is that information system interoperability will remain an unfulfilled hope until health reforms effectively address the governance (accountability), structural and process barriers to interoperability of health care delivery. The ascendency of Web 2.0 and 3.0, although still unproven, signals the opportunity to accelerate patients' access to health information and their health record. Policy suggestions for simultaneously advancing health system delivery and information system interoperability are posited.

  8. Interactions between barrier islands and backbarrier marshes affect island system response to sea level rise: Insights from a coupled model

    Science.gov (United States)

    Walters, David; Moore, Laura J.; Duran Vinent, Orencio; Fagherazzi, Sergio; Mariotti, Giulio

    2014-09-01

    Interactions between backbarrier marshes and barrier islands will likely play an important role in determining how low-lying coastal systems respond to sea level rise and changes in storminess in the future. To assess the role of couplings between marshes and barrier islands under changing conditions, we develop and apply a coupled barrier island-marsh model (GEOMBEST+) to assess the impact of overwash deposition on backbarrier marsh morphology and of marsh morphology on rates of island migration. Our model results suggest that backbarrier marsh width is in a constant state of change until either the backbarrier basin becomes completely filled or backbarrier marsh deposits have completely eroded away. Results also suggest that overwash deposition is an important source of sediment, which allows existing narrow marshes to be maintained in a long-lasting alternate state (~500 m wide in the Virginia Barrier Islands) within a range of conditions under which they would otherwise disappear. The existence of a narrow marsh state is supported by observations of backbarrier marshes along the eastern shore of Virginia. Additional results suggest that marshes reduce accommodation in the backbarrier bay, which, in turn, decreases island migration rate. As climate change results in sea level rise, and the increased potential for intense hurricanes resulting in overwash, it is likely that these couplings will become increasingly important in determining future system behavior.

  9. Pattern Recognition Methods and Features Selection for Speech Emotion Recognition System

    Science.gov (United States)

    Partila, Pavol; Voznak, Miroslav; Tovarek, Jaromir

    2015-01-01

    The impact of the classification method and features selection for the speech emotion recognition accuracy is discussed in this paper. Selecting the correct parameters in combination with the classifier is an important part of reducing the complexity of system computing. This step is necessary especially for systems that will be deployed in real-time applications. The reason for the development and improvement of speech emotion recognition systems is wide usability in nowadays automatic voice controlled systems. Berlin database of emotional recordings was used in this experiment. Classification accuracy of artificial neural networks, k-nearest neighbours, and Gaussian mixture model is measured considering the selection of prosodic, spectral, and voice quality features. The purpose was to find an optimal combination of methods and group of features for stress detection in human speech. The research contribution lies in the design of the speech emotion recognition system due to its accuracy and efficiency. PMID:26346654

  10. Pattern Recognition Methods and Features Selection for Speech Emotion Recognition System

    Directory of Open Access Journals (Sweden)

    Pavol Partila

    2015-01-01

    Full Text Available The impact of the classification method and features selection for the speech emotion recognition accuracy is discussed in this paper. Selecting the correct parameters in combination with the classifier is an important part of reducing the complexity of system computing. This step is necessary especially for systems that will be deployed in real-time applications. The reason for the development and improvement of speech emotion recognition systems is wide usability in nowadays automatic voice controlled systems. Berlin database of emotional recordings was used in this experiment. Classification accuracy of artificial neural networks, k-nearest neighbours, and Gaussian mixture model is measured considering the selection of prosodic, spectral, and voice quality features. The purpose was to find an optimal combination of methods and group of features for stress detection in human speech. The research contribution lies in the design of the speech emotion recognition system due to its accuracy and efficiency.

  11. A SCHEME FOR TEMPLATE SECURITY AT FEATURE FUSION LEVEL IN MULTIMODAL BIOMETRIC SYSTEM

    Directory of Open Access Journals (Sweden)

    Arvind Selwal

    2016-09-01

    Full Text Available Biometric is the science of human recognition based upon using their biological, chemical or behavioural traits. These systems are used in many real life applications simply from biometric based attendance system to providing security at very sophisticated level. A biometric system deals with raw data captured using a sensor and feature template extracted from raw image. One of the challenges being faced by designers of these systems is to secure template data extracted from the biometric modalities of the user and protect the raw images. To minimize spoof attacks on biometric systems by unauthorised users one of the solutions is to use multi-biometric systems. Multi-modal biometric system works by using fusion technique to merge feature templates generated from different modalities of the human. In this work a new scheme is proposed to secure template during feature fusion level. Scheme is based on union operation of fuzzy relations of templates of modalities during fusion process of multimodal biometric systems. This approach serves dual purpose of feature fusion as well as transformation of templates into a single secured non invertible template. The proposed technique is cancelable and experimentally tested on a bimodal biometric system comprising of fingerprint and hand geometry. Developed scheme removes the problem of an attacker learning the original minutia position in fingerprint and various measurements of hand geometry. Given scheme provides improved performance of the system with reduction in false accept rate and improvement in genuine accept rate.

  12. Perceived barriers of heart failure nurses and cardiologists in using clinical decision support systems in the treatment of heart failure patients

    OpenAIRE

    Vries, Arjen E. de; van der Wal, Martje H. L.; Nieuwenhuis, Maurice M. W.; Richard M. de Jong; Rene B. van Dijk; Jaarsma, Tiny; Hillege, Hans L; Jorna, Rene J.

    2013-01-01

    Background Clinical Decision Support Systems (CDSSs) can support guideline adherence in heart failure (HF) patients. However, the use of CDSSs is limited and barriers in working with CDSSs have been described as a major obstacle. It is unknown if barriers to CDSSs are present and differ between HF nurses and cardiologists. Therefore the aims of this study are; 1. Explore the type and number of perceived barriers of HF nurses and cardiologists to use a CDSS in the treatment of HF patients. 2. ...

  13. Decontamination systems information and research program -- Literature review in support of development of standard test protocols and barrier design models for in situ formed barriers project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    The US Department of Energy is responsible for approximately 3,000 sites in which contaminants such as carbon tetrachloride, trichlorethylene, perchlorethylene, non-volatile and soluble organic and insoluble organics (PCBs and pesticides) are encountered. In specific areas of these sites radioactive contaminants are stored in underground storage tanks which were originally designed and constructed with a 30-year projected life. Many of these tanks are now 10 years beyond the design life and failures have occurred allowing the basic liquids (ph of 8 to 9) to leak into the unconsolidated soils below. Nearly one half of the storage tanks located at the Hanford Washington Reservation are suspected of leaking and contaminating the soils beneath them. The Hanford site is located in a semi-arid climate region with rainfall of less than 6 inches annually, and studies have indicated that very little of this water finds its way to the groundwater to move the water down gradient toward the Columbia River. This provides the government with time to develop a barrier system to prevent further contamination of the groundwater, and to develop and test remediation systems to stabilize or remove the contaminant materials. In parallel to remediation efforts, confinement and containment technologies are needed to retard or prevent the advancement of contamination plumes through the environment until the implementation of remediation technology efforts are completed. This project examines the various confinement and containment technologies and protocols for testing the materials in relation to their function in-situ.

  14. Courier Receipts Retrieval System Design Combining the Inverse Zernike Moments and the SIFT Features

    Directory of Open Access Journals (Sweden)

    Wenyin Ni

    2012-11-01

    Full Text Available In response to the demand of the logistics industry’s application, a retrieval algorithm for logistics bill is proposed which combines the local feature with the global feature of images, which solved the problem of rotation positioning and applied to a set of practical courier receipts retrieval system. By using the scale invariance principle of the local features combined with Zernike invariant moments of the global features, we can quickly calculate the image rotating angle and make the exact match. Experimental results show that this method not only keeps the well precision and recall ratio ability of SIFT features, but also reduces the counting times which are required by fine matching.

  15. Changes in skin barrier during treatment with systemic alitretinoin: focus on skin susceptibility and stratum corneum ceramides

    DEFF Research Database (Denmark)

    Jungersted, Jakob Mutanu; Høgh, Julie Kaae; Hellgren, Lars

    2010-01-01

    Alitretinoin is a new drug for systemic treatment of chronic hand eczema. Previous functional tests of skin topically treated with retinoids have indicated impaired skin barrier function, but no data are available on barrier parameters after systemic alitretinoin treatment. To investigate the eff....... No significant changes in stratum corneum lipids were found after 2 months of treatment. In conclusion, systemic alitretinoin does not influence skin susceptibility to irritants or the ceramide profile of stratum corneum....... the effect of systemic alitretinoin on skin barrier function and response to irritants, a secondary objective was to determine if changes occur in the lipid profile of stratum corneum after treatment with systemic alitretinoin. We conducted an open clinical intervention study on eight people ascribed......) was performed on the volar forearm and evaluated by trans-epidermal water loss (TEWL), erythema, and a cyanoacrylate skin sample was obtained for lipid analysis. We found no significant changes in response to SLS irritation as evaluated by TEWL and erythema, after treatment with alitretinoin for 2 months...

  16. PS1-56: Beyond Barriers: Systemic Constraints Limiting Sexual Health Care for Breast Cancer Survivors

    Science.gov (United States)

    Halley, Meghan; May, Suepattra; Rendle, Katharine; Frosch, Dominick; Kurian, Allison

    2013-01-01

    Background/Aims Sexual health problems represent one of the most frequently experienced and longest-lasting effects of breast cancer treatment, but research suggests that providers rarely discuss sexual health with their patients. Existing research examining barriers to addressing the sexual health concerns of cancer patients has focused on discrete characteristics of the provider-patient interaction without considering the broader context in which these interactions occur. Drawing on focus group discussions with breast cancer survivors, we explore how foundational cultural and structural characteristics of the healthcare system may be preventing breast cancer survivors from addressing their sexual health concerns. Methods Five focus groups were conducted with breast cancer survivors receiving support services at a breast cancer advocacy and resource organization in Northern California. Each group focused on a different aspect of treatment including: 1) diagnosis; 2) surgery and reconstruction; 3) chemotherapy; 4) radiation; and 5) survivorship. An interview guide for each topic area was used to elicit participants’ thoughts, opinions and experiences of breast cancer treatment. Analysis utilized inductive techniques incorporating elements of Grounded Theory to identify salient themes that emerged in the discussions. Results An average of eight women participated in each focus group, and women were allowed to participate in more than one group, for a total of 21 participants. Participants’ discussions illustrated three core ways in which cultural and structural characteristics of the healthcare system prevented them from addressing their sexual health concerns, including: 1) the structure of cancer care led to participants being disconnected from the healthcare system at the time when sexual side effects most commonly emerged; 2) when their sexual side effects did emerge, the highly specialized structure of the biomedical system made it difficult for patients to

  17. A Neuro-Fuzzy System for Extracting Environment Features Based on Ultrasonic Sensors

    Directory of Open Access Journals (Sweden)

    Evelio José González

    2009-12-01

    Full Text Available In this paper, a method to extract features of the environment based on ultrasonic sensors is presented. A 3D model of a set of sonar systems and a workplace has been developed. The target of this approach is to extract in a short time, while the vehicle is moving, features of the environment. Particularly, the approach shown in this paper has been focused on determining walls and corners, which are very common environment features. In order to prove the viability of the devised approach, a 3D simulated environment has been built. A Neuro-Fuzzy strategy has been used in order to extract environment features from this simulated model. Several trials have been carried out, obtaining satisfactory results in this context. After that, some experimental tests have been conducted using a real vehicle with a set of sonar systems. The obtained results reveal the satisfactory generalization properties of the approach in this case.

  18. A process planning system with feature based neural network search strategy for aluminum extrusion die manufacturing

    CERN Document Server

    Butdee, S; Tichkiewitch, Serge

    2009-01-01

    Aluminum extrusion die manufacturing is a critical task for productive improvement and increasing potential of competition in aluminum extrusion industry. It causes to meet the efficiency not only consistent quality but also time and production cost reduction. Die manufacturing consists first of die design and process planning in order to make a die for extruding the customer's requirement products. The efficiency of die design and process planning are based on the knowledge and experience of die design and die manufacturer experts. This knowledge has been formulated into a computer system called the knowledge-based system. It can be reused to support a new die design and process planning. Such knowledge can be extracted directly from die geometry which is composed of die features. These features are stored in die feature library to be prepared for producing a new die manufacturing. Die geometry is defined according to the characteristics of the profile so we can reuse die features from the previous similar p...

  19. Research on Wind Turbine Generator Dynamic Reliability Test System Based on Feature Recognition

    Directory of Open Access Journals (Sweden)

    Bin Wang

    2013-09-01

    Full Text Available Wind power resource development is increasingly becoming the focus of the current research and development in various countries' relevant scientific institutions. To make sure the secure and reliable operation of wind turbine generator, the study develops the wind turbine generator dynamic reliability test system. When the fault of gearbox and spindle occurs, their features of vibration signals are special. According to the feature recognition technology, the application of time and frequency domain model identification method has practical significance to the test system. Based on Bayesian network fault diagnosis method, the vibration feature recognition system of wind turbine generator is constructed. Finally, the paper uses GPRS technology to realize the wireless transmission of operation information. The wind turbine generator dynamic reliability test system is built based on GPRS technology to realize automatic control and remote intelligent monitoring and to ensure the safe and stable operation of wind farms.

  20. Facilitators and barriers to doing workplace mental health research: Case study of acute psychological trauma in a public transit system.

    Science.gov (United States)

    Links, Paul S; Bender, Ash; Eynan, Rahel; O'Grady, John; Shah, Ravi

    2016-03-10

    The Acute Psychological Trauma (APT) Study was a collaboration between an acute care hospital, a specialized multidisciplinary program designed to meet the mental health needs of injured workers, and a large urban public transit system. The overall purpose was to evaluate a Best Practices Intervention (BPI) for employees affected by acute psychological trauma compared to a Treatment as Usual (TAU) group. The specific purpose is to discuss facilitators and barriers that were recognized in implementing and carrying out mental health research in a workplace setting. Over the course of the APT study, a joint implementation committee was responsible for day-to-day study operations and made regular observations on the facilitators and barriers that arose throughout the study. The facilitators to this study included the longstanding relationships among the partners, increased recognition for the need of mental health research in the workplace, and the existence of a community advisory committee. The significant barriers to doing this study of mental health research in the workplace included differences in organizational culture, inconsistent union support, co-interventions, and stigma. Researchers and funding agencies need to be flexible and provide additional resources in order to overcome the barriers that can exist doing workplace mental health research.

  1. Blood-brain barrier models and their relevance for a successful development of CNS drug delivery systems: a review.

    Science.gov (United States)

    Bicker, Joana; Alves, Gilberto; Fortuna, Ana; Falcão, Amílcar

    2014-08-01

    During the research and development of new drugs directed at the central nervous system, there is a considerable attrition rate caused by their hampered access to the brain by the blood-brain barrier. Throughout the years, several in vitro models have been developed in an attempt to mimic critical functionalities of the blood-brain barrier and reliably predict the permeability of drug candidates. However, the current challenge lies in developing a model that retains fundamental blood-brain barrier characteristics and simultaneously remains compatible with the high throughput demands of pharmaceutical industries. This review firstly describes the roles of all elements of the neurovascular unit and their influence on drug brain penetration. In vitro models, including non-cell based and cell-based models, and in vivo models are herein presented, with a particular emphasis on their methodological aspects. Lastly, their contribution to the improvement of brain drug delivery strategies and drug transport across the blood-brain barrier is also discussed.

  2. WORKING FEATURES OF POWER SOURCE SYSTEMS – A MULTIPLE CURRENT PULSE GENERATOR

    Directory of Open Access Journals (Sweden)

    Shs.V. Argun

    2013-04-01

    Full Text Available An analysis of circuit designs as to connecting a magnetic pulse action tool to a power source has been carried out. Design features of a magnetic pulse installation control and monitoring system in a multiple current pulse mode have been revealed. The description of the control and monitoring system block diagrams has been presented.

  3. Engineered Barrier System - Long-term Stability of Buffer and Backfill. Synthesis and extended abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Apted, Mick; Arthur, Randy [Monitor Scientific LLC, Denver, CO (United States); Savage, Dave [Quintessa Ltd., Nottingham (GB)] (eds.)

    2005-09-15

    SKI is preparing to review the license applications being developed by the Swedish Nuclear Fuel and Waste Management Company (SKB) for an encapsulation plant and a deep repository for the geological disposal of spent nuclear fuel. As part of its preparation, SKI is conducting a series of technical workshops on key aspects of the Engineered Barrier System (EBS) of the repository. This workshop concerns the longterm stability of the buffer and the backfill. Previous workshops have addressed the overall concept for long-term integrity of the EBS, the manufacturing, testing and QA of the EBS and the performance confirmation for the EBS. The goal of this work is to achieve a comprehensive overview of all aspects of SKB's EBS work prior to the handling of forthcoming license applications. The reports from the EBS workshops will be used as one important basis in future review work. The workshops involve the gathering of a sufficient number of independent experts in different subjects of relevance to the particular aspect of EBS. A workshop starts with presentations and discussions among these experts. Following this, SKB presents recent results and responds to questions as part of an informal hearing. Finally, the independent experts and the SKI staff examine the SKB responses from different viewpoints. This report aims to summarise the issues discussed at the buffer and backfill workshop and to extract the essential viewpoints that have been expressed. The report is not a comprehensive record of the discussions and individual statements made by workshop participants should be regarded as opinions rather than proven facts. This reports includes apart from the workshop synthesis, questions to SKB identified prior or during the workshop, and extended abstracts for introductory presentations.

  4. Experimental Studies of Engineered Barrier Systems Conducted at Los Alamos National Laboratory (FY16)

    Energy Technology Data Exchange (ETDEWEB)

    Caporuscio, Florie Andre [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Norskog, Katherine Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Maner, James [Univ. of Oklahoma, Norman, OK (United States). School of Geology and Geophysics; Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Palaich, Sarah [Univ. of California, Los Angeles, CA (United States). Dept. of Earth, Planetary, and Space Sciences; Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cheshire, Michael C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-08-04

    Over the past five years the Used Fuel Campaign has investigated Engineered Barrier Systems (EBS) at higher heat loads (up to 300°C) and pressure (150 bar). This past year experimental work was hindered due to a revamping of the hydrothermal lab. Regardless, two experiments were run this past year, EBS-18 and EBS-19. EBS-18 was run using Low Carbon Steel (LCS) and opalinus clay in addition to the bentonite and opalinus brine. Many of the past results were confirmed in EBS-18, such as the restriction of illite formation due to the bulk chemistry, pyrite degradation, and zeolite formation dependent on the bentonite and opalinus clay. The LCS show vast amounts of pit corrosion (over 100μm of corrosion in six weeks), leading a corrosion rate of 1083 μm/year. In addition, a mineral goethite, an iron-bearing hydroxide, formed in the pits of the LCS. Preliminary results from EBS-19 water chemistry are included but SEM imaging, micro probe and XRD are still needed for further results. Copper corrosion was investigated further and over 850 measurements were taken. It was concluded that pitting and pyrite degradation drastically increase the corrosion rate from 0.12 to 0.39 μm/day. However, the growth of a layer of the mineral chalcocite is thought to subdue the corrosion rate to 0.024 μm/day as observed in the EBS-13, a sixth month experiment. This document presents the findings of this past year.

  5. Experimental Studies of Engineered Barrier Systems Conducted at Los Alamos National Laboratory (FY16)

    Energy Technology Data Exchange (ETDEWEB)

    Caporuscio, Florie Andre [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Norskog, Katherine Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Maner, James [Univ. of Oklahoma, Norman, OK (United States). School of Geology and Geophysics; Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Palaich, Sarah [Univ. of California, Los Angeles, CA (United States). Dept. of Earth, Planetary, and Space Sciences; Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cheshire, Michael C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-08-04

    Over the past five years the Used Fuel Campaign has investigated Engineered Barrier Systems (EBS) at higher heat loads (up to 300°C) and pressure (150 bar). This past year experimental work was hindered due to a revamping of the hydrothermal lab. Regardless, two experiments were run this past year, EBS-18 and EBS-19. EBS-18 was run using Low Carbon Steel (LCS) and opalinus clay in addition to the bentonite and opalinus brine. Many of the past results were confirmed in EBS-18 such as the restriction of illite formation due to the bulk chemistry, pyrite degradation, and zeolite formation dependent on the bentonite and opalinus clay. The LCS show vast amounts of pit corrosion over 100μm of corrosion in six weeks, leading a corrosion rate of 1083 μm/year. In addition, a mineral goethite, an iron bearing hydroxide, formed in the pits of the LCS. Preliminary results from EBS-19 water chemistry are included but SEM imaging, micro probe and XRD are still needed for further results. Copper corrosion was investigated further and over 850 measurements were taken. It was concluded that pitting and pyrite degradation drastically increase the corrosion rate from 0.12 to 0.39 μm/day. However, the growth of a layer of the mineral chalcocite is thought to subdue the corrosion rate to 0.024 μm/day as observed in the EBS-13 a sixth month experiment. This document presents the findings of this past year.

  6. DeepCAD: A Computer-Aided Diagnosis System for Mammographic Masses Using Deep Invariant Features

    Directory of Open Access Journals (Sweden)

    Qaisar Abbas

    2016-10-01

    Full Text Available The development of a computer-aided diagnosis (CAD system for differentiation between benign and malignant mammographic masses is a challenging task due to the use of extensive pre- and post-processing steps and ineffective features set. In this paper, a novel CAD system is proposed called DeepCAD, which uses four phases to overcome these problems. The speed-up robust features (SURF and local binary pattern variance (LBPV descriptors are extracted from each mass. These descriptors are then transformed into invariant features. Afterwards, the deep invariant features (DIFs are constructed in supervised and unsupervised fashion through multilayer deep-learning architecture. A fine-tuning step is integrated to determine the features, and the final decision is performed via softmax linear classifier. To evaluate this DeepCAD system, a dataset of 600 region-of-interest (ROI masses including 300 benign and 300 malignant masses was obtained from two publicly available data sources. The performance of DeepCAD system is compared with the state-of-the-art methods in terms of area under the receiver operating characteristics (AUC curve. The difference between AUC of DeepCAD and other methods is statistically significant, as it demonstrates a sensitivity (SN of 92%, specificity (SP of 84.2%, accuracy (ACC of 91.5% and AUC of 0.91. The experimental results indicate that the proposed DeepCAD system is reliable for providing aid to radiologists without the need for explicit design.

  7. Analysis of electrode shift effects on wavelet features embedded in a myoelectric pattern recognition system.

    Science.gov (United States)

    Fontana, Juan M; Chiu, Alan W L

    2014-01-01

    Myoelectric pattern recognition systems can translate muscle contractions into prosthesis commands; however, the lack of long-term robustness of such systems has resulted in low acceptability. Specifically, socket misalignment may cause disturbances related to electrodes shifting from their original recording location, which affects the myoelectric signals (MES) and produce degradation of the classification performance. In this work, the impact of such disturbances on wavelet features extracted from MES was evaluated in terms of classification accuracy. Additionally, two principal component analysis frameworks were studied to reduce the wavelet feature set. MES from seven able-body subjects and one subject with congenital transradial limb loss were studied. The electrode shifts were artificially introduced by recording signals during six sessions for each subject. A small drop in classification accuracy from 93.8% (no disturbances) to 88.3% (with disturbances) indicated that wavelet features were able to adapt to the variability introduced by electrode shift disturbances. The classification performance of the reduced feature set was significantly lower than the performance of the full wavelet feature set. The results observed in this study suggest that the effect of electrode shift disturbances on the MES can potentially be mitigated by using wavelet features embedded in a pattern recognition system.

  8. The Development of Environmental Barrier Coating Systems for SiC-SiC Ceramic Matrix Composites: Environment Effects on the Creep and Fatigue Resistance

    Science.gov (United States)

    Zhu, Dongming; Ghosn, Louis J.

    2014-01-01

    Topics covered include: Environmental barrier coating system development: needs, challenges and limitations; Advanced environmental barrier coating systems (EBCs) for CMC airfoils and combustors; NASA EBC systems and material system evolutions, Current turbine and combustor EBC coating emphases, Advanced development, processing, testing and modeling, EBC and EBC bond coats: recent advances; Design tool and life prediction of coated CMC components; Advanced CMC-EBC rig demonstrations; Summary and future directions.

  9. Functionally gradient materials for thermal barrier coatings in advanced gas turbine systems

    Energy Technology Data Exchange (ETDEWEB)

    Banovic, S.W.; Barmak, K.; Chan, H.M. [Lehigh Univ., Bethlehem, PA (United States)] [and others

    1995-10-01

    New designs for advanced gas turbine engines for power production are required to have higher operating temperatures in order to increase efficiency. However, elevated temperatures will increase the magnitude and severity of environmental degradation of critical turbine components (e.g. combustor parts, turbine blades, etc{hor_ellipsis}). To offset this problem, the usage of thermal barrier coatings (TBCs) has become popular by allowing an increase in maximum inlet temperatures for an operating engine. Although thermal barrier technology is over thirty years old, the principle failure mechanism is the spallation of the ceramic coating at or near the ceramic/bond coat interface. Therefore, it is desirable to develop a coating that combines the thermal barrier qualities of the ceramic layer and the corrosion protection by the metallic bond coat without the detrimental effects associated with the localization of the ceramic/metal interface to a single plane.

  10. Identification of neuronal and angiogenic growth factors in an in vitro blood-brain barrier model system: Relevance in barrier integrity and tight junction formation and complexity.

    Science.gov (United States)

    Freese, Christian; Hanada, Sanshiro; Fallier-Becker, Petra; Kirkpatrick, C James; Unger, Ronald E

    2017-05-01

    We previously demonstrated that the co-cultivation of endothelial cells with neural cells resulted in an improved integrity of the in vitro blood-brain barrier (BBB), and that this model could be useful to evaluate the transport properties of potential central nervous system disease drugs through the microvascular brain endothelial. In this study we have used real-time PCR, fluorescent microscopy, protein arrays and enzyme-linked immunosorbent assays to determine which neural- and endothelial cell-derived factors are produced in the co-culture and improve the integrity of the BBB. In addition, a further improvement of the BBB integrity was achieved by adjusting serum concentrations and growth factors or by the addition of brain pericytes. Under specific conditions expression of angiogenic, angiostatic and neurotrophic factors such as endostatin, pigment epithelium derived factor (PEDF/serpins-F1), tissue inhibitor of metalloproteinases (TIMP-1), and vascular endothelial cell growth factor (VEGF) closely mimicked the in vivo situation. Freeze-fracture analysis of these cultures demonstrated the quality and organization of the endothelial tight junction structures and their association to the two different lipidic leaflets of the membrane. Finally, a multi-cell culture model of the BBB with a transendothelial electrical resistance up to 371 (±15) Ω×cm(2) was developed, which may be useful for preliminary screening of drug transport across the BBB and to evaluate cellular crosstalk of cells involved in the neurovascular unit.

  11. Effects of barrier fluctuation on the tunneling dynamics in the presence of classical chaos in a mixed quantum-classical system

    Indian Academy of Sciences (India)

    Aparna Saha; Bidhan Chandra Bag; Pranab Sarkar

    2007-03-01

    We present a numerical investigation of the tunneling dynamics of a particle moving in a bistable potential with fluctuating barrier which is coupled to a non-integrable classical system and study the interplay between classical chaos and barrier fluctuation in the tunneling dynamics. We found that the coupling of the quantum system with the classical subsystem decreases the tunneling rate irrespective of whether the classical subsystem is regular or chaotic and also irrespective of the fact that whether the barrier fluctuates or not. Presence of classical chaos always enhances the tunneling rate constant. The effect of barrier fluctuation on the tunneling rate in a mixed quantum-classical system is to suppress the tunneling rate. In contrast to the case of regular subsystem, the suppression arising due to barrier fluctuation is more visible when the subsystem is chaotic.

  12. Perceived barriers of heart failure nurses and cardiologists in using clinical decision support systems in the treatment of heart failure patients

    NARCIS (Netherlands)

    de Vries, Arjen E.; van der Wal, Martje H. L.; Nieuwenhuis, Maurice M. W.; de Jong, Richard M.; van Dijk, Rene B.; Jaarsma, Tiny; Hillege, Hans L.; Jorna, Rene J.

    2013-01-01

    Background: Clinical Decision Support Systems (CDSSs) can support guideline adherence in heart failure (HF) patients. However, the use of CDSSs is limited and barriers in working with CDSSs have been described as a major obstacle. It is unknown if barriers to CDSSs are present and differ between HF

  13. Establishment and Application of Early Warning System for Flood and Debris Flow Triggered by Rapid Erosion of Natural Barrier

    Science.gov (United States)

    Kaji, A.; Mizuno, H.; Yamakoshi, T.; Ishizuka, T.

    2012-04-01

    A large amount of mass of land from a mountain slides into a gorge and a river, depositing on the bed. The formation of such natural barrier provides a dam called "a natural dam", allowing water to accumulate in the upstream. People living in the downstream of basin are at risk of flood triggered by the dam break. Recently, many people have been at such risk emerged by earthquakes and heavy rainfall therefore they have been requesting to establish an early warning system for such flood risk. By analyzing the past case of the formations and the natural dam breaks in Japan, it was found that the surface flow on the natural dam eroded the deposition rapidly and the accumulated water and the deposition started to flow downstream in many cases. So that an alert should be issued by forecasting when the accumulated water in the upstream starts to flow on the deposition. In order to forecast the timing, we have to take into consideration of the difference between the water volume of flowing to the lake from the upstream basin and that of seeping into the deposition. Our final target is to develop a method for estimating the two previous quantities. In the first step, we report the result of analysis of the past cases in Japan. We focused on the two natural dams in the Yuhama village in Miyagi prefecture and in the Nagatono village in Nara prefecture. The natural dam in Yuhama village was formed by a deep-seated landslide triggered by the earthquake in 2008, and the natural dam in Nagatono was formed by a deep-seated landslide triggered by heavy rainfall in 2011. In the Yuhama case, the water level of the accumulated water had been rising until it reached to the top of the natural dam. In the Nagatono case, the water level had been rising during rainfall, however the water level had been dropping after the rainfall. The difference between the water volume of flowing in and that of flowing out from the natural dam caused the tendencies. We are going to analyze the soil

  14. A new approach to the non-oxidative conversion of gaseous alkanes in a barrier discharge and features of the reaction mechanism

    Science.gov (United States)

    Kudryashov, S.; Ryabov, A.; Shchyogoleva, G.

    2016-01-01

    A new approach to the non-oxidative conversion of C1-C4 alkanes into gaseous and liquid products in a barrier discharge is proposed. It consists in inhibiting the formation of deposits on the reactor electrode surfaces due to the addition of distilled water into the flow of hydrocarbon gases. The energy consumption on hydrocarbon conversion decreases from methane to n-butane from ~46 to 35 eV molecule-1. The main gaseous products of the conversion of light alkanes are hydrogen and C2-C4 hydrocarbons. The liquid reaction products contain C5+ alkanes with a predominantly isomeric structure. The results of modeling the kinetics of chemical reactions show that an increase in the molecular weight of the reaction products is mainly due to processes involving CH2 radical and the recombination of alkyl radicals.

  15. Elementary Analysis on the Technological Features of an Engineering Equipment Facile Diagnosis System

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    From the point of systemic engineering, the general properties of an engineering equipment fault diagnosis system and the studying object of diagnosis engineering were discussed. With the developing course of fault diagnosis technology, the relationship be-tween facile diagnosis system and diagnosis engineering were also discussed. The basic structure and feature of a facile diagnosis system were discussed, and the isomorphic of a facile diagnosis system and precise diagnosis system was presented. The facile diagnosis requires the perfection of method, pertinence and apriority of knowledge , adaptability of the object being diagnosed and the approach to the aim of the diagnosis result, as well as the outstanding of main functions.

  16. Face verification system for Android mobile devices using histogram based features

    Science.gov (United States)

    Sato, Sho; Kobayashi, Kazuhiro; Chen, Qiu

    2016-07-01

    This paper proposes a face verification system that runs on Android mobile devices. In this system, facial image is captured by a built-in camera on the Android device firstly, and then face detection is implemented using Haar-like features and AdaBoost learning algorithm. The proposed system verify the detected face using histogram based features, which are generated by binary Vector Quantization (VQ) histogram using DCT coefficients in low frequency domains, as well as Improved Local Binary Pattern (Improved LBP) histogram in spatial domain. Verification results with different type of histogram based features are first obtained separately and then combined by weighted averaging. We evaluate our proposed algorithm by using publicly available ORL database and facial images captured by an Android tablet.

  17. Increased inspiratory esophagogastric junction pressure in systemic sclerosis: An add-on to antireflux barrier

    Science.gov (United States)

    Nobre e Souza, Miguel Ângelo; Bezerra, Patrícia Carvalho; Nobre, Rivianny Arrais; Holanda, Esther Studart da Fonseca; dos Santos, Armênio Aguiar

    2015-01-01

    AIM: To investigate crural diaphragm (CD) function in systemic sclerosis (SSc) using high-resolution manometry and standardized inspiratory maneuvers. METHODS: Eight SSc volunteers (average age, 40.1 years; one male) and 13 controls (average age, 32.2 years; six males) participated in the study. A high-resolution manometry/impedance system measured the esophagus and esophagogastric junction (EGJ) pressure profile during swallows and two respiratory maneuvers: sinus arrhythmia maneuver (SAM; the average of six EGJ peak pressures during 5-s deep inhalations) and threshold maneuver (TM; the EGJ peak pressures during forced inhalation under 12 and 24 cmH2O loads). Inspiratory diaphragm lowering (IDL) was taken as the displacement of the EGJ high-pressure zone during the SAM. RESULTS: SSc patients had lower mean lower esophageal sphincter pressure than controls during normal breathing (19.7 ± 2.8 mmHg vs 32.2 ± 2.7 mmHg, P = 0.007). Sinus arrhythmia maneuver pressure was higher in SSc patients than in controls (142.6 ± 9.4 mmHg vs 104.6 ± 13.8 mmHg, P = 0.019). Sinus arrhythmia maneuver pressure normalized to IDL was also higher in SSc patients than in controls (83.8 ± 13.4 mmHg vs 37.5 ± 6.9 mmHg, P = 0.005). Threshold maneuver pressures normalized to IDL were also greater in SSc patients than in controls (TM 12 cmH2O: 85.1 ± 16.4 mmHg vs 43.9 ± 6.3 mmHg, P = 0.039; TM 24 cmH2O: 85.2 ± 16.4 mmHg vs 46.2 ± 6.6 mmHg, P = 0.065). Inspiratory diaphragm lowering in SSc patients was less than in controls (2.1 ± 0.3 cm vs 3 ± 0.2 cm, P = 0.011). CONCLUSION: SSc patients had increased inspiratory EGJ pressure. This is an add-on to EGJ pressure and indicates that the antireflux barrier can be trained. PMID:25717239

  18. Generalized Discriminant Analysis algorithm for feature reduction in Cyber Attack Detection System

    Directory of Open Access Journals (Sweden)

    Shailendra Singh

    2009-10-01

    Full Text Available This Generalized Discriminant Analysis (GDA has provided an extremely powerful approach to extracting non-linear features. The network traffic data provided for the design of intrusion detection system always are large with ineffective information, thus we need to remove the worthless information from the original high dimensional database. To improve the generalization ability, we usually generate a small set of features from the original input variables by feature extraction. The conventional Linear Discriminant Analysis (LDA feature reduction technique has its limitations. It is not suitable for non-linear dataset. Thus we propose an efficient algorithm based on the Generalized Discriminant Analysis (GDA feature reduction technique which is novel approach used in the area of cyber attack detection. This not only reduces the number of the input features but also increases the classification accuracy and reduces the training and testing time of the classifiers by selecting most discriminating features. We use Artificial Neural Network (ANN and C4.5 classifiers to compare the performance of the proposed technique. The result indicates the superiority of algorithm.

  19. A Registration Scheme for Multispectral Systems Using Phase Correlation and Scale Invariant Feature Matching

    Directory of Open Access Journals (Sweden)

    Hanlun Li

    2016-01-01

    Full Text Available In the past few years, many multispectral systems which consist of several identical monochrome cameras equipped with different bandpass filters have been developed. However, due to the significant difference in the intensity between different band images, image registration becomes very difficult. Considering the common structural characteristic of the multispectral systems, this paper proposes an effective method for registering different band images. First we use the phase correlation method to calculate the parameters of a coarse-offset relationship between different band images. Then we use the scale invariant feature transform (SIFT to detect the feature points. For every feature point in a reference image, we can use the coarse-offset parameters to predict the location of its matching point. We only need to compare the feature point in the reference image with the several near feature points from the predicted location instead of the feature points all over the input image. Our experiments show that this method does not only avoid false matches and increase correct matches, but also solve the matching problem between an infrared band image and a visible band image in cases lacking man-made objects.

  20. Barriers to screening mammography.

    Science.gov (United States)

    Sarma, Elizabeth A

    2015-01-01

    Breast cancer (BRCA) is the second most commonly diagnosed cancer among women in the USA, and mammography is an effective means for the early detection of BRCA. Identifying the barriers to screening mammography can inform research, policy and practice aiming to increase mammography adherence. A literature review was conducted to determine common barriers to screening mammography adherence. PsycINFO and PubMed databases were searched to identify studies published between 2000 and 2012 that examined barriers associated with reduced mammography adherence. Three thematic groups of barriers, based on social ecology, were identified from the literature: healthcare system-level, social and individual-level barriers. Researchers must consider screening behaviour in context and, therefore, should simultaneously consider each level of barriers when attempting to understand screening behaviour and create interventions to increase mammography adherence.

  1. Use of barrier membranes and systemic antibiotics in the treatment of intraosseous defects

    NARCIS (Netherlands)

    Loos, BG; Louwerse, PHG; van Winkelhoff, AJ; Burger, W; Gilijamse, M; Hart, AAM; van der Velden, U

    2002-01-01

    Objectives: Current literature is ambivalent on the use of barrier membranes for regeneration of intraosseous defects. One of the reasons for unpredictable results may be related to infection before, during and after the surgical procedure. Therefore, the purpose of the present controlled study was

  2. Quantifying system safety: A comparison of the SBOAT & Safety Barrier Manager tools

    DEFF Research Database (Denmark)

    Hansen, Zaza Nadja Lee; Duijm, Nijs Jan; Markert, Frank

    2015-01-01

    This paper presents two software tools for analyzing safety risks, SBOAT (Stochastic BPMN Optimisation and Analysis Tool) and SBM (SafetyBarrierManagerr). SBOAT employs principles from stochastic model checking to allow for the quantitative verification of workflows. SBM supports the creation...

  3. Systems pharmacology and blood-brain barrier functionality in Parkinson's disease

    NARCIS (Netherlands)

    Ravenstijn, Paulien Gerarda Maria

    2009-01-01

    Parkinson’s disease is a progressive neurodegenerative disease, which is composed of many components, each caused by interplay of a number of genetic and nongenetic causes. As the blood-brain barrier (BBB) is a key player in the relationship between plasma and brain pharmacokinetics, the influences

  4. No runoff, no soil loss: soil and water conservation in hedgerow barrier systems.

    NARCIS (Netherlands)

    Kiepe, P.

    1995-01-01

    Land degradation by water erosion represents a serious, and fast increasing, environmental threat. Hedgerow barriers control water erosion through the presence of the tree stem and through an increase in infiltration beneath the hedgerow. The infiltration rate beneath hedgerows is 3-8 times higher t

  5. Morphological response of a barrier island system on a catastrophic event

    DEFF Research Database (Denmark)

    Fruergaard, Mikkel; Kroon, Aart

    2016-01-01

    The AD 1634 North Sea storm is one of the most catastrophic storms along the Wadden Sea coast of Denmark. In this study we show how pre-1634 storm morphology exerted a strong control on the resulting post-storm coastal morphology. Erosional responses associated with the storm were barrier breachi...

  6. Modeling the Hydrogeochemical Transport of Radionuclides through Engineered Barriers System in the Proposed LLW Disposal Site of Taiwan - 12082

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Wen-Sheng [Hydrotech Research Institute, National Taiwan University, Taipei, Taiwan (China); Liu, Chen-Wuing; Tsao, Jui-Hsuan [Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan (China); Li, Ming-Hsu [Institute of Hydrological and Oceanic Sciences, National Central University, Jhongli, Taiwan (China)

    2012-07-01

    A proposed site for final disposal of low-level radioactive waste located in Daren Township of Taitung County along the southeastern coast has been on the selected list in Taiwan. The geology of the Daren site consists of argillite and meta-sedimentary rocks. A mined cavern design with a tunnel system of 500 m below the surface is proposed. Concrete is used as the main confinement material for the engineered barrier. To investigate the hydrogeochemical transport of radionuclides through engineered barriers system, HYDROGEOCHEM5.0 model was applied to simulate the complex chemical interactions among radionuclides, the cement minerals of the concrete, groundwater flow, and transport in the proposed site. The simulation results showed that the engineered barriers system with the side ditch efficiently drained the ground water and lowered the concentration of the concrete degradation induced species (e.g., hydrogen ion, sulfate, and chloride). The velocity of groundwater observed at side ditch gradually decreased with time due to the fouling of pore space by the mineral formation of ettringite and thaumasite. The short half-life of Co-60, Sr-90 and Cs-137 significantly reduced the concentrations, whereas the long half-life of I-129(1.57x10{sup 7} years) and Am-241(432 years) remain stable concentrations at the interface of waste canister and concrete barrier after 300 years. The mineral saturation index (SI) was much less than zero due to the low aqueous concentration of radionuclide, so that the precipitation formation of Co-60, Sr-90, I-129, Cs-137 and Am-241 related minerals were not found. The effect of adsorption/desorption (i.e., surface complexation model) could be a crucial geochemical mechanism for the modeling of liquid-solid phase behavior of radionuclide in geochemically dynamic environments. Moreover, the development of advanced numerical models that are coupled with hydrogeochemical transport and dose assessment of radionuclide is required in the future

  7. A Study on the Thermal-Hydro-Mechanical Behaviors in the Engineered Barrier System of a HLW Repository: Engineering-scale Validation Test

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae-Owan; Kwon, S. K.; Park, J. H.; Cho, W. J.; Lee, Jae-Owan

    2007-06-15

    The T-H-M processes in the engineered barrier system are one of the major issues in the performance assessment of a HLW repository. In this study, it was conducted to design and construct the engineering-scale test facility which was a third-scale of the reference disposal system, and to investigate THM behavior of the engineered barrier system using the test facility. The computer modeling and interpreting methodology for THM behavior were also developed.

  8. Dynamic features analysis for the large-scale logistics system warehouse-out operation

    Science.gov (United States)

    Yao, Can-Zhong; Lin, Ji-Nan; Liu, Xiao-Feng; Zheng, Xu-Zhou

    2014-12-01

    In the paper, we research on the behavior dynamics for the large-scale logistics system warehouse-out operation systematically. First, we discover that steel products warehouse-out of different warehouses in a large-scale logistics system can be characterized by burst, and the warehouse-out inter-event time follows the power-law distribution with exponents close to α=2.5, which differs from the two classical models proposed by Barabasi (2005) and Vazquez (2005) respectively. By analyzing the warehouse-out inter-event time distribution of the products in one certain large-scale logistics system, we further discuss burst features and mechanisms of logistics system. Additionally, we find that in population behaviors, burst features can be explained by the priority that rooted in holidays and interior task scheduling. However, warehouse-out behaviors of active individuals do not show any features of burst. Further, we find that warehouse-out quantity of steel products follows Fractal Brownian motion with the HURST exponent higher than 0.5 by means of R/S, which infers that the quantity of products in a logistics system is not only guided by prices in the present market, but also related closely to the previous quantity of warehouse-out. Based on V statistic, we compare memory length of different products in warehouses. Finally, we apply complex networks visibility graphs for further validation of fractal features in a logistics system and find that almost every visibility graph exhibits small-world and scale-free features. Both R/S and complex networks visibility graphs reinforce that the warehouse-out quantity of products in a logistics system is not a random walk process, but contains intrinsic regularities and long-term correlation between present and previous warehouse-out quantity.

  9. Numerical determination of the interfacial energy and nucleation barrier of curved solid-liquid interfaces in binary systems.

    Science.gov (United States)

    Kundin, Julia; Choudhary, Muhammad Ajmal

    2016-07-01

    The phase-field crystal (PFC) technique is a widely used approach for modeling crystal growth phenomena with atomistic resolution on mesoscopic time scales. We use a two-dimensional PFC model for a binary system based on the work of Elder et al. [Phys. Rev. B 75, 064107 (2007)PRBMDO1098-012110.1103/PhysRevB.75.064107] to study the effect of the curved, diffuse solid-liquid interface on the interfacial energy as well as the nucleation barrier. The calculation of the interfacial energy and the nucleation barrier certainly depends on the proper definition of the solid-liquid dividing surface and the corresponding nucleus size. We define the position of the sharp interface at which the interfacial energy is to be evaluated by using the concept of equimolar dividing surface (r^{e}) and the minimization of the interfacial energy (r^{s}). The comparison of the results based on both radii shows that the difference r^{e}-r^{s} is always positive and has a limit for large cluster sizes which is comparable to the Tolman length. Furthermore, we found the real nucleation barrier for small cluster sizes, which is defined as a function of the radius r^{s}, and compared it with the classical nucleation theory. The simulation results also show that the extracted interfacial energy as function of both radii is independent of system size, and this dependence can be reasonably described by the nonclassical Tolman formula with a positive Tolman length.

  10. Extracting features for power system vulnerability assessment from wide-area measurements

    Energy Technology Data Exchange (ETDEWEB)

    Kamwa, I. [Hydro-Quebec, Varennes, PQ (Canada). IREQ; Pradhan, A.; Joos, G. [McGill Univ., Montreal, PQ (Canada)

    2006-07-01

    Many power systems now operate close to their stability limits as a result of deregulation. Some utilities have chosen to install phason measurement units (PMUs) to monitor power system dynamics. The synchronized phasors of different areas of power systems available through a wide-area measurement system (WAMS) are expected to provide an effective security assessment tool as well as a stabilizing control action for inter-area oscillations and a system protection scheme (SPS) to evade possible blackouts. This paper presented tool extracting features for vulnerability assessment from WAMS-data. A Fourier-transform based technique was proposed for monitoring inter-area oscillations. FFT, wavelet transform and curve fitting approaches were investigated to analyze oscillatory signals. A dynamic voltage stability prediction algorithm was proposed for control action. An integrated framework was then proposed to assess a power system through extracted features from WAMS-data on first swing stability, voltage stability and inter-area oscillations. The centre of inertia (COI) concept was applied to the angle of voltage phasor. Prony analysis was applied to filtered signals to extract the damping coefficients. The minimum post-fault voltage of an area was considered for voltage stability, and an algorithm was used to monitor voltage stability issues. A data clustering technique was applied to classify the features in a group for improved system visualization. The overall performance of the technique was examined using a 67-bus system with 38 PMUs. The method used to extract features from both frequency and time domain analysis was provided. The test power system was described. The results of 4 case studies indicated that adoption of the method will be beneficial for system operators. 13 refs., 2 tabs., 13 figs.

  11. Health system and societal barriers for gestational diabetes mellitus (GDM) services - lessons from World Diabetes Foundation supported GDM projects

    DEFF Research Database (Denmark)

    Nielsen, Karoline Kragelund; de Courten, Maximilian; Kapur, Anil

    2012-01-01

    Background Maternal mortality and morbidity remains high in many low- and middle-income countries (LMIC). Gestational Diabetes Mellitus (GDM) represents an underestimated and unrecognised impediment to optimal maternal health in LMIC; left untreated – it also has severe consequences for the offsp......Background Maternal mortality and morbidity remains high in many low- and middle-income countries (LMIC). Gestational Diabetes Mellitus (GDM) represents an underestimated and unrecognised impediment to optimal maternal health in LMIC; left untreated – it also has severe consequences...... for the offspring. A better understanding of the barriers hindering detection and treatment of GDM is needed. Based on experiences from World Diabetes Foundation (WDF) supported GDM projects this paper seeks to investigate societal and health system barriers to such efforts. Methods Questionnaires were filled out...

  12. Symmetric splitting for the system /sup 32/S+/sup 238/U at energies near and below the barrier

    Energy Technology Data Exchange (ETDEWEB)

    Freifelder, R.; Braun-Munzinger, P.; DeYoung, P.; Schicker, R.; Sen, S.; Stachel, J.

    1987-06-01

    The total capture cross section for the system /sup 32/S+/sup 238/U has been measured at energies from 0.93 to 1.08 times the s-wave interaction barrier by detecting coincident fission fragments following full momentum transfer reactions. The subbarrier cross section cannot be reproduced by a one-dimensional barrier penetration model. Using a quantum mechanical coupled channels model, good agreement is obtained. The measured angular distributions of fission fragments were compared to the predictions of saddle and scission point transition state theory. Saddle point transition state model calculations fail to reproduce the data, while scission point transition state calculations are in agreement with their qualitative trend. Evidence for nonequilibrium processes is presented.

  13. The Impact of New Features on Positioning Technology in LTE-A System

    Directory of Open Access Journals (Sweden)

    Zhang Bo

    2015-01-01

    Full Text Available As the location based services develop, more and more researches have been focused on the positioning technologies in mobile networks. The long term evolution advanced (LTE-A system, commercialized as the 4th generation (4G mobile communication system, is based on the following key features: the orthogonal frequency division multiplexing (OFDM, the relay, the multiple input multiple outputs (MIMO, the carrier aggregation (CA, and the coordinated multipoint transmission and reception (CoMP. In this paper, the impact of these features on the existing positioning technology specified in the LTE-A standards is systematically investigated. Moreover, two approaches are proposed to take full advantage of these features in terms of positioning technologies and the key positioning parameters, including the reference signal time difference (RSTD in the observed time difference of arrival (OTDOA technology and user equipment receiving time subtracting transmitting time (UE Rx-Tx in the enhanced cell identity (E-CID technology.

  14. Health system barriers and facilitators to medication adherence for the secondary prevention of cardiovascular disease: a systematic review

    Science.gov (United States)

    Banerjee, Amitava; Khandelwal, Shweta; Nambiar, Lavanya; Saxena, Malvika; Peck, Victoria; Moniruzzaman, Mohammed; Faria Neto, Jose Rocha; Quinto, Katherine Curi; Smyth, Andrew; Leong, Darryl; Werba, José Pablo

    2016-01-01

    Background Secondary prevention is cost-effective for cardiovascular disease (CVD), but uptake is suboptimal. Understanding barriers and facilitators to adherence to secondary prevention for CVD at multiple health system levels may inform policy. Objectives To conduct a systematic review of barriers and facilitators to adherence/persistence to secondary CVD prevention medications at health system level. Methods Included studies reported effects of health system level factors on adherence/persistence to secondary prevention medications for CVD (coronary artery or cerebrovascular disease). Studies considered at least one of β blockers, statins, angiotensin–renin system blockers and aspirin. Relevant databases were searched from 1 January 1966 until 1 October 2015. Full texts were screened for inclusion by 2 independent reviewers. Results Of 2246 screened articles, 25 studies were included (12 trials, 11 cohort studies, 1 cross-sectional study and 1 case–control study) with 132 140 individuals overall (smallest n=30, largest n=63 301). 3 studies included upper middle-income countries, 1 included a low middle-income country and 21 (84%) included high-income countries (9 in the USA). Studies concerned established CVD (n=4), cerebrovascular disease (n=7) and coronary heart disease (n=14). Three studies considered persistence and adherence. Quantity and quality of evidence was limited for adherence, persistence and across drug classes. Studies were concerned with governance and delivery (n=19, including 4 trials of fixed-dose combination therapy, FDC), intellectual resources (n=1), human resources (n=1) and health system financing (n=4). Full prescription coverage, reduced copayments, FDC and counselling were facilitators associated with higher adherence. Conclusions High-quality evidence on health system barriers and facilitators to adherence to secondary prevention medications for CVD is lacking, especially for low-income settings. Full prescription coverage

  15. MEMBRANOUS FLOWS IN GAS-LIQUID COLLECTORS-REGENERATORS OF SOLAR ABSORPTIVE SYSTEMS FEATURES

    Directory of Open Access Journals (Sweden)

    Doroshenko А.V.

    2009-12-01

    Full Text Available Article is devoted to the creation of new generation of solar collectors of the gas-liquid type, intended for use in alternative refrigerating and conditioning systems of drying-evaporating type with direct solar regeneration of absorbent. Special attention is given to the study of membranous flows features on inclined surfaces, including questions of such flows stability.

  16. The intrinsic features of Environmental Management Systems that facilitate adoption and encourage innovation in primary industries

    NARCIS (Netherlands)

    Carruthers, Genevieve; Vanclay, Frank

    2012-01-01

    This paper examines the theoretical underpinnings of the adoption of innovations, and applies this knowledge to the uptake of Environmental Management Systems (EMS) amongst Australian farmers. We examine the specific features of the EMS process that might encourage or inhibit EMS adoption. We also c

  17. The Main Features and the Key Challenges of the Education System in Taiwan

    Science.gov (United States)

    Chien, Chiu-Kuei Chang; Lin, Lung-Chi; Chen, Chun-Fu

    2013-01-01

    Taiwan has undergone radical innovation of its educational system in the wake of political liberalization and democratization, with a request for a change in the idea which diverts from "de-centralization" to "individualization." The reforms have led to two main features of pluralism and generalization of education in our…

  18. Quality control and patient dosimetry in digital radiology. On line system: new features and transportability.

    Science.gov (United States)

    Vano, E; Ten, J I; Fernandez, J M; Prieto, C; Ordiales, J M; Martinez, D

    2008-01-01

    New features have been added to a system (QCONLINE) for auditing patient dosimetric and technical parameters 'on line', working on a digital radiology department and using the information contained in the DICOM header of some modalities. The audit of other parameters than patient doses have been included, setting alarm conditions to alert on malfunction of the X-ray system or bad operation modes, in addition to the evaluation of patient doses. A new module to analyse, collect and process the relevant information transferred by the modality performed procedure step (MPPS) service has been launched. Several examples with the exploitation of the new features are presented. The transportability of the system has been tested in two remote hospitals during several months. The new MPPS module has demonstrated to be a good tool to complement the information existing in the DICOM header. The system allows to help in the optimisation of digital radiology departments managing patient dosimetry and procedure data in real time.

  19. Prediction of microRNAs involved in immune system diseases through network based features.

    Science.gov (United States)

    Prabahar, Archana; Natarajan, Jeyakumar

    2017-01-01

    MicroRNAs are a class of small non-coding regulatory RNA molecules that modulate the expression of several genes at post-transcriptional level and play a vital role in disease pathogenesis. Recent research shows that a range of miRNAs are involved in the regulation of immunity and its deregulation results in immune mediated diseases such as cancer, inflammation and autoimmune diseases. Computational discovery of these immune miRNAs using a set of specific features is highly desirable. In the current investigation, we present a SVM based classification system which uses a set of novel network based topological and motif features in addition to the baseline sequential and structural features to predict immune specific miRNAs from other non-immune miRNAs. The classifier was trained and tested on a balanced set of equal number of positive and negative examples to show the discriminative power of our network features. Experimental results show that our approach achieves an accuracy of 90.2% and outperforms the classification accuracy of 63.2% reported using the traditional miRNA sequential and structural features. The proposed classifier was further validated with two immune disease sub-class datasets related to multiple sclerosis microarray data and psoriasis RNA-seq data with higher accuracy. These results indicate that our classifier which uses network and motif features along with sequential and structural features will lead to significant improvement in classifying immune miRNAs and hence can be applied to identify other specific classes of miRNAs as an extensible miRNA classification system.

  20. Image reporting and characterization system for ultrasound features of thyroid nodules: Multicentric Korean retrospective study

    Energy Technology Data Exchange (ETDEWEB)

    Kwak, Jin Young [Dept. of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul (Korea, Republic of); Jung, In Kyung [Dept. of Biostatistics, Yonsei University College of Medicine, Seoul (Korea, Republic of); Beak, Jung Hwan [Dept. of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seou (Korea, Republic of); and others

    2013-01-15

    The objective of this retrospective study was to develop and validate a simple diagnostic prediction model by using ultrasound (US) features of thyroid nodules obtained from multicenter retrospective data. Patient data were collected from 20 different institutions and the data included 2000 thyroid nodules from 1796 patients. For developing a diagnostic prediction model to estimate the malignant risk of thyroid nodules using suspicious malignant US features, we developed a training model in a subset of 1402 nodules from 1260 patients. Several suspicious malignant US features were evaluated to create the prediction model using a scoring tool. The scores for such US features were estimated by calculating odds ratios, and the risk score of malignancy for each thyroid nodule was defined as the sum of these individual scores. Later, we verified the usefulness of developed scoring system by applying into the remaining 598 nodules from 536 patients. Among 2000 tumors, 1268 were benign and 732 were malignant. In our multiple regression analysis models, the following US features were statistically significant for malignant nodules when using the training data set: hypoechogenicity, marked hypoechogenicity, non-parallel orientation, microlobulated or spiculated margin, ill-defined margins, and microcalcifications. The malignancy rate was 7.3% in thyroid nodules that did not have suspicious-malignant features on US. Area under the receiver operating characteristic (ROC) curve was 0.867, which shows that the US risk score help predict thyroid malignancy well. In the test data set, the malignancy rates were 6.2% in thyroid nodules without malignant features on US. Area under the ROC curve of the test set was 0.872 when using the prediction model. The predictor model using suspicious malignant US features may be helpful in risk stratification of thyroid nodules.

  1. Blanch Resistant and Thermal Barrier NiAl Coating Systems for Advanced Copper Alloys

    Science.gov (United States)

    Raj, Sai V. (Inventor)

    2005-01-01

    A method of forming an environmental resistant thermal barrier coating on a copper alloy is disclosed. The steps include cleansing a surface of a copper alloy, depositing a bond coat on the cleansed surface of the copper alloy, depositing a NiAl top coat on the bond coat and consolidating the bond coat and the NiAl top coat to form the thermal barrier coating. The bond coat may be a nickel layer or a layer composed of at least one of copper and chromium-copper alloy and either the bond coat or the NiAl top coat or both may be deposited using a low pressure or vacuum plasma spray.

  2. THE ROTATION BARRIER OF ELECTRON SPIN PROBE IN THE STUDY OF POLYMER SYSTEM

    Institute of Scientific and Technical Information of China (English)

    YU Tongyin; GUO Shiqing; GE Mingtao

    1984-01-01

    In the study of molecular motion of polymer by means of ESR in combination with spin probe,owing to that the ESR spectrum depicts only the behavior of spin probe, the information obtained is of indirect nature. Hence the relationship between them must first be investigated before any conclusion could be drawn. In this paper, two parameters TR and CR are introduced to characterize the changing of tumbling rate of spin probe, and the concept of rotation barrier of spin probe is proposed. It is considered that the magnitude of the rotation barrier is determined by the internal cavity size and distribution in polymer. When the temperature is raised, the size and distribution of the cavities change accordingly, thus the tumbling of spin probe changes gradually from a slower to a higher rate.

  3. The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis.

    LENUS (Irish Health Repository)

    Keen, H I

    2008-05-01

    Painful osteoarthritis (OA) of the hand is common and a validated ultrasound (US) scoring system would be valuable for epidemiological and therapeutic outcome studies. US is increasingly used to assess peripheral joints, though most of the US focus in rheumatic diseases has been on rheumatoid arthritis. We aimed to develop a preliminary US hand OA scoring system, initially focusing on relevant pathological features with potentially high reliability.

  4. Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines.

    Science.gov (United States)

    Drolez, Aurore; Vandenhaute, Elodie; Julien, Sylvain; Gosselet, Fabien; Burchell, Joy; Cecchelli, Roméo; Delannoy, Philippe; Dehouck, Marie-Pierre; Mysiorek, Caroline

    2016-01-01

    Around 7-17% of metastatic breast cancer patients will develop brain metastases, associated with a poor prognosis. To reach the brain parenchyma, cancer cells need to cross the highly restrictive endothelium of the Blood-Brain Barrier (BBB). As treatments for brain metastases are mostly inefficient, preventing cancer cells to reach the brain could provide a relevant and important strategy. For that purpose an in vitro approach is required to identify cellular and molecular interaction mechanisms between breast cancer cells and BBB endothelium, notably at the early steps of the interaction. However, while numerous studies are performed with in vitro models, the heterogeneity and the quality of BBB models used is a limitation to the extrapolation of the obtained results to in vivo context, showing that the choice of a model that fulfills the biological BBB characteristics is essential. Therefore, we compared pre-established and currently used in vitro models from different origins (bovine, mice, human) in order to define the most appropriate tool to study interactions between breast cancer cells and the BBB. On each model, the BBB properties and the adhesion capacities of breast cancer cell lines were evaluated. As endothelial cells represent the physical restriction site of the BBB, all the models consisted of endothelial cells from animal or human origins. Among these models, only the in vitro BBB model derived from human stem cells both displayed BBB properties and allowed measurement of meaningful different interaction capacities of the cancer cell lines. Importantly, the measured adhesion and transmigration were found to be in accordance with the cancer cell lines molecular subtypes. In addition, at a molecular level, the inhibition of ganglioside biosynthesis highlights the potential role of glycosylation in breast cancer cells adhesion capacities.

  5. A CAD System for Lesion Detection in Cervigram Based on Laws Textural Feature

    Directory of Open Access Journals (Sweden)

    RamaPraba P.S

    2014-01-01

    Full Text Available Cervical cancer is the second most common cancer among the women worldwide. A computer aided diagnosis system can help colposcopist to analyze cervical images more accurately. This work aims to detect lesion in cervical images based on Laws textural feature and nearest neighbor classifier and it can be used as a diagnostic tool. The images used for the detection of cervical cancer are taken by using colposcope which magnifies the cells of cervix. The Laws textural features are extracted from the cervical images and input to nearest neighbor classifier. A totally 240 images are used for the evaluation and an overall accuracy of 96% is obtained.

  6. Yttria-stabilized zirkonia / gadolinium zirconate double-layer plasma-sprayed thermal barrier coating systems (TBCs)

    Energy Technology Data Exchange (ETDEWEB)

    Bakan, Emine

    2015-07-01

    Thermal barrier coating (TBC) research and development is driven by the desirability of further increasing the maximum inlet temperature in a gas turbine engine. A number of new top coat ceramic materials have been proposed during the last decades due to limited temperature capability (1200 C) of the state-of-the-art yttria-stabilized zirconia (7 wt. % Y{sub 2}O{sub 3}-ZrO{sub 2}, YSZ) at long term operation. Zirconate pyrochlores of the large lanthanides((Gd → La){sub 2}Zr{sub 2}O{sub 7}) have been particularly attractive due to their higher temperature phase stability than that of the YSZ. Nonetheless, the issues related with the implementation of pyrochlores such as low fracture toughness and formation of deleterious interphases with thermally grown oxide (TGO, Al{sub 2}O{sub 3}) were reported. The implication was the requirement of an interlayer between the pyrochlores and TGO, which introduced double-layer systems to the TBC literature. Furthermore, processability issues of pyrochlores associated with the different evaporation rates of lanthanide oxides and zirconia resulting in unfavorable composition variations in the coatings were addressed in different studies. After all, although the material properties are available, there is a paucity of data in the literature concerning the properties of the coatings made of pyrochlores. From the processability point of view the most reported pyrochlore is La{sub 2}Zr{sub 2}O{sub 7}. Hence, the goal of this research was to investigate plasma-sprayed Gd{sub 2}Zr{sub 2}O{sub 7} (GZO) coatings and YSZ/GZO double-layer TBC systems. Three main topics were examined based on processing, performance and properties: (i) the plasma spray processing of the GZO and its impact on the microstructural and compositional properties of the GZO coatings; (ii) the cycling lifetime of the YSZ/GZO double-layer systems under thermal gradient at a surface temperature of 1400 C; (iii) the properties of the GZO and YSZ coatings such as

  7. Geometric and featural systems, separable and combined: Evidence from reorientation in people with Williams syndrome

    Science.gov (United States)

    Ferrara, Katrina; Landau, Barbara

    2015-01-01

    Spatial reorientation by humans and other animals engages geometric representations of surface layouts as well as featural landmarks; however, the two types of information are thought to be behaviorally and neurally separable. In this paper, we examine the use of these two types of information during reorientation among children and adults with Williams syndrome (WS), a genetic disorder accompanied by abnormalities in brain regions that support use of both geometry and landmarks. Previous studies of reorientation in adolescents and adults with WS have shown deficits in the ability to use geometry for reorientation, but intact ability to use features, suggesting that the two systems can be differentially impaired by genetic disorder. Using a slightly modified layout, we found that many WS participants could use geometry, and most could use features along with geometry. However, the developmental trajectories for the two systems were quite different from one other, and different from those found in typical development. Purely geometric responding was not correlated with age in WS, and search processes appeared similar to those in typically developing (TD) children. In contrast, use of features in combination with geometry was correlated with age in WS, and search processes were distinctly different from TD children. The results support the view that use of geometry and features stem from different underlying mechanisms, that the developmental trajectories and operation of each are altered in WS, and that combination of information from the two systems is atypical. Given brain abnormalities in regions supporting the two kinds of information, our findings suggest that the co-operation of the two systems is functionally altered in this genetic syndrome. PMID:26275835

  8. Identifying barriers to mental health system improvements: an examination of community participation in assertive community treatment programs

    Directory of Open Access Journals (Sweden)

    Wakefield Patricia A

    2011-11-01

    Full Text Available Abstract Background Integrating the best available evidence into program standards is essential if system-wide improvements in the delivery of community-based mental health services are to be achieved. Since the beginning of the Assertive Community Treatment (ACT program movement, program standards have included a role for the community. In particular, ACT program standards have sought to ensure that members of the local community are involved in governance and that former clients participate in service delivery as "Peer Support Specialists". This paper reports on the extent to which ACT program standards related to community participation have been implemented and identifies barriers to full compliance. Methods Qualitative and quantitative data were collected through a telephone survey of ACT Program Coordinators in Ontario, Canada, using a census sample of the existing 66 ACT programs. A thematic approach to content analysis was used to analyze respondents' qualitative comments. Quantitative data were analyzed using SPSS 16.0 and included means, frequencies, independent t-tests and Pearson Correlations. Results An 85% response rate was achieved. Of the 33 program standards, the two that received the lowest perceived compliance ratings were the two standards directly concerning community participation. Specifically, the standard to have a functioning Community Advisory Body and the standard requiring the inclusion of a Peer Support Specialist. The three major themes that emerged from the survey data with respect to the barriers to fully implementing the Community Advisory Body were: external issues; standard related issues; and, organizational/structural related issues. The three major themes concerning barriers to implementing the Peer Support Specialist role were: human resource related issues; organizational/structural related issues; and, standard related issues. Conclusions The reasons for low compliance of ACT programs with community

  9. The Calibration Algorithm of a 3D Color Measurement System based on the Line Feature

    Directory of Open Access Journals (Sweden)

    Ganhua Li

    2009-10-01

    Full Text Available This paper describes a novel 3 dimensional color measurement system. After 3 kinds of geometrical features are analyzed, the line features were selected. A calibration board with right-angled triangle outline was designed to improve the calibration precision. For this system, two algorithms are presented. One is the calibration algorithm between 2 dimensional laser range finder (2D LRF, while the other is for 2D LRF and the color camera. The result parameters were obtained through solving the constrain equations by the correspond data between the 2D LRF and other two sensors. The 3D color reconstruction experiments of real data prove the effectiveness and the efficient of the system and the algorithms.

  10. Design Features behind Success of the Ecosystem Management Decision Support System and Future Development

    Directory of Open Access Journals (Sweden)

    Keith Reynolds

    2014-12-01

    Full Text Available The Ecosystem Management Decision Support (EMDS system is an application framework for designing and implementing spatially enabled knowledge-based decision support systems for environmental analysis and planning at any geographic scale(s. The system integrates state-of-the-art geographic information system, as well as knowledge-based reasoning and decision modeling, technologies to provide decision support for the adaptive management process of ecosystem management. It integrates a logic engine to perform landscape evaluations, and a decision engine for developing management priorities. The logic component: (1 reasons about large, abstract, multi-faceted ecosystem management problems; (2 performs useful evaluations with incomplete information; (3 evaluates the influence of missing information, and (4 determines priorities for missing information. The planning component determines priorities for management activities, taking into account not only ecosystem condition, but also criteria that account for logistical concerns of potential management actions. Both components include intuitive diagnostic features that facilitate communicating modeling results to a broad audience. Features of the system design that have figured in its success over the past 20 years are highlighted, together with design features planned for the next several versions needed to provide spatial decision support for adaptive management under climate change.

  11. Exploration of available feature detection and identification systems and their performance on radiographs

    Science.gov (United States)

    Wantuch, Andrew C.; Vita, Joshua A.; Jimenez, Edward S.; Bray, Iliana E.

    2016-10-01

    Despite object detection, recognition, and identification being very active areas of computer vision research, many of the available tools to aid in these processes are designed with only photographs in mind. Although some algorithms used specifically for feature detection and identification may not take explicit advantage of the colors available in the image, they still under-perform on radiographs, which are grayscale images. We are especially interested in the robustness of these algorithms, specifically their performance on a preexisting database of X-ray radiographs in compressed JPEG form, with multiple ways of describing pixel information. We will review various aspects of the performance of available feature detection and identification systems, including MATLABs Computer Vision toolbox, VLFeat, and OpenCV on our non-ideal database. In the process, we will explore possible reasons for the algorithms' lessened ability to detect and identify features from the X-ray radiographs.

  12. Prediction of protein secondary structure using probability based features and a hybrid system.

    Science.gov (United States)

    Ghanty, Pradip; Pal, Nikhil R; Mudi, Rajani K

    2013-10-01

    In this paper, we propose some co-occurrence probability-based features for prediction of protein secondary structure. The features are extracted using occurrence/nonoccurrence of secondary structures in the protein sequences. We explore two types of features: position-specific (based on position of amino acid on fragments of protein sequences) as well as position-independent (independent of amino acid position on fragments of protein sequences). We use a hybrid system, NEUROSVM, consisting of neural networks and support vector machines for classification of secondary structures. We propose two schemes NSVMps and NSVM for protein secondary structure prediction. The NSVMps uses position-specific probability-based features and NEUROSVM classifier whereas NSVM uses the same classifier with position-independent probability-based features. The proposed method falls in the single-sequence category of methods because it does not use any sequence profile information such as position specific scoring matrices (PSSM) derived from PSI-BLAST. Two widely used datasets RS126 and CB513 are used in the experiments. The results obtained using the proposed features and NEUROSVM classifier are better than most of the existing single-sequence prediction methods. Most importantly, the results using NSVMps that are obtained using lower dimensional features, are comparable to those by other existing methods. The NSVMps and NSVM are finally tested on target proteins of the critical assessment of protein structure prediction experiment-9 (CASP9). A larger dataset is used to compare the performance of the proposed methods with that of two recent single-sequence prediction methods. We also investigate the impact of presence of different amino acid residues (in protein sequences) that are responsible for the formation of different secondary structures.

  13. A regression-based Kansei engineering system based on form feature lines for product form design

    Directory of Open Access Journals (Sweden)

    Yan Xiong

    2016-06-01

    Full Text Available When developing new products, it is important for a designer to understand users’ perceptions and develop product form with the corresponding perceptions. In order to establish the mapping between users’ perceptions and product design features effectively, in this study, we presented a regression-based Kansei engineering system based on form feature lines for product form design. First according to the characteristics of design concept representation, product form features–product form feature lines were defined. Second, Kansei words were chosen to describe image perceptions toward product samples. Then, multiple linear regression and support vector regression were used to construct the models, respectively, that predicted users’ image perceptions. Using mobile phones as experimental samples, Kansei prediction models were established based on the front view form feature lines of the samples. From the experimental results, these two predict models were of good adaptability. But in contrast to multiple linear regression, the predict performance of support vector regression model was better, and support vector regression is more suitable for form regression prediction. The results of the case showed that the proposed method provided an effective means for designers to manipulate product features as a whole, and it can optimize Kansei model and improve practical values.

  14. HMM based Offline Signature Verification system using ContourletTransform and Textural features

    Directory of Open Access Journals (Sweden)

    K N PUSHPALATHA

    2014-07-01

    Full Text Available Handwritten signatures occupy a very special place in the identification of an individual and it is a challenging task because of the possible variations in directions and shapes of the constituent strokes of written samples. In this paper we investigated offline verifications system based on fusion of contourlet transform, directional features and Hidden Markov Model (HMM as classifier. The handwritten signature image is preprocessed for noise removal and a two level contourlet transform is applied to get feature vector. The textural features are computed and concatenated with coefficients of contourlet transform to form the final feature vector. A two level contourlet transform is applied to get feature vector after the signature images of both query and database are preprocessed for noise removal. The classification results are computed using HTK tool with HMM classifier. The experimental results are computed using GPDS-960 database images to get the parameters like False Rejection Rate (FRR, False Acceptance Rate (FAR and Total Success Rate (TSR. The results show that the values of FRR and FAR are improved compared to the existing algorithm.

  15. A Probabilistic Feature Map-Based Localization System Using a Monocular Camera

    Directory of Open Access Journals (Sweden)

    Hyungjin Kim

    2015-08-01

    Full Text Available Image-based localization is one of the most widely researched localization techniques in the robotics and computer vision communities. As enormous image data sets are provided through the Internet, many studies on estimating a location with a pre-built image-based 3D map have been conducted. Most research groups use numerous image data sets that contain sufficient features. In contrast, this paper focuses on image-based localization in the case of insufficient images and features. A more accurate localization method is proposed based on a probabilistic map using 3D-to-2D matching correspondences between a map and a query image. The probabilistic feature map is generated in advance by probabilistic modeling of the sensor system as well as the uncertainties of camera poses. Using the conventional PnP algorithm, an initial camera pose is estimated on the probabilistic feature map. The proposed algorithm is optimized from the initial pose by minimizing Mahalanobis distance errors between features from the query image and the map to improve accuracy. To verify that the localization accuracy is improved, the proposed algorithm is compared with the conventional algorithm in a simulation and realenvironments

  16. Origin of additional spectral features in modulated reflectance spectra of 2-dimensional semiconductor systems

    Science.gov (United States)

    Mukherjee, Amlan; Ghosh, Sandip

    2014-03-01

    High resolution photoreflectance (PR) spectroscopy study on a single GaAs/AlGaAs quantum well representing a two-dimensional (2D) system, shows additional distinct spectral features on the high energy side of the first confined heavy-hole and light-hole exciton transitions. The PR experiments involved a special dual detection technique which significantly improved the measurement sensitivity. Photoluminescence excitation spectroscopy data on the sample showed broadened step-like features around these energies. A detailed lineshape analysis, including first principles simulations, was performed to understand the origins of these additional PR spectral features. They are shown to arise primarily from inhomogeneously broadened first excited state transition of the excitons, rather than from a change in the joint density of states at the exciton continuum edge. The analysis suggests that such features are more likely in the case of 2D excitons as compared to 3D excitons in bulk material. Apart from its significance for post-growth characterization, identification of these additional PR features enables direct estimation of the exciton binding energy.

  17. Recycler barrier RF buckets

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, C.M.; /Fermilab

    2011-03-01

    The Recycler Ring at Fermilab uses a barrier rf systems for all of its rf manipulations. In this paper, I will give an overview of historical perspective on barrier rf system, the longitudinal beam dynamics issues, aspects of rf linearization to produce long flat bunches and methods used for emittance measurements of the beam in the RR barrier rf buckets. Current rf manipulation schemes used for antiproton beam stacking and longitudinal momentum mining of the RR beam for the Tevatron collider operation are explained along with their importance in spectacular success of the Tevatron luminosity performance.

  18. Hematopoietic tumors of the female genital system: imaging features with pathologic correlation.

    Science.gov (United States)

    Salem, Usama; Menias, Christine O; Shaaban, Akram; Bhosale, Priya R; Youssef, Ayda; Elsayes, Khaled M

    2014-08-01

    Various hematopoietic neoplasms can involve the female genital system. The most common hematological malignancy that involves the female genital system is lymphoma and secondary involvement is more common than primary genital lymphoma. Rarely, leukemic infiltration and extramedullary plasmacytomas of the female genital tract may also occur. Being infrequent, these lesions are commonly misdiagnosed radiologically. Therefore, understanding these malignancies of the female genital system and recognizing their imaging features are of utmost clinical importance. Although definitive diagnosis can be made only by histological analysis, imaging of these tumors plays an important role in detecting lesion extensions, guiding biopsies, staging disease, planning therapy, and detecting recurrence.

  19. Specific features pertinent to modeling of hydraulic systems containing control members

    Science.gov (United States)

    Tverskoy, Yu. S.; Marshalov, E. D.

    2014-09-01

    The theoretical principles applied for modeling of hydraulic systems fitted with control members that allow a hydraulic line's specific features (topology) to be taken into account are considered. Such modeling opens the possibility to predict the actual flow (throttling) characteristics at early design stages and timely introduce the appropriate corrections in pipeline topology. The modeling problem is solved with the use of generalized thermodynamic analysis methods. The mathematical models of hydraulic systems containing control members are brought to the level of real-time simulation models, which can be used for setting up computation experiments for achieving better performance of automatic closed-loop control systems.

  20. Thermal/residual stress in an electron beam physical vapor deposited thermal barrier coating system

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, J.; Jordan, E.H.; Barber, B.; Gell, M. [Univ. of Connecticut, Storrs, CT (United States)

    1998-10-09

    Elastic-plastic finite element models are used to define the thermal/residual stress state responsible for the observed failure behavior of an electron beam physical vapor deposited yttria stabilized zirconia thermal barrier coating on a Pt-Al bond coat. The failures were observed to start at grain boundary ridges, some of which evolved into oxide filled cavities. Finite element models are made of the actual interface geometries through the use of metallographic sectioning and imaging processing. There is a one to one correspondence of calculated tension in the oxide layer and the observed localized damage. Purely elastic analysis failed to show some important tensile regions associated with the observed failure.

  1. Formation of white-eye pattern with microdischarge in an air dielectric barrier discharge system

    CERN Document Server

    He, Yafeng; Liu, Weili; Wang, Hongfang; Zhao, Zengchao; Fan, Weili

    2011-01-01

    We report on the first observation of white-eye pattern in an air dielectric barrier discharge. The patterned discharges undergo a development as following: random spots - quasihexagonal pattern - hexagonal pattern (type I) - hexagonal pattern (type II) - white-eye pattern - chaos as the voltage is increased. The spatiotemporal characteristics of patterned discharges are investigated by using an optical method. Results show that the two discharge modes, uniform mode and filamentary mode, are actually two different spatial presentations of the same origin: the microdischarge. From the viewpoint of pattern dynamics, the white-eye pattern results from a 3-wave resonance interaction.

  2. A two-view ultrasound CAD system for spina bifida detection using Zernike features

    Science.gov (United States)

    Konur, Umut; Gürgen, Fikret; Varol, Füsun

    2011-03-01

    In this work, we address a very specific CAD (Computer Aided Detection/Diagnosis) problem and try to detect one of the relatively common birth defects - spina bifida, in the prenatal period. To do this, fetal ultrasound images are used as the input imaging modality, which is the most convenient so far. Our approach is to decide using two particular types of views of the fetal neural tube. Transcerebellar head (i.e. brain) and transverse (axial) spine images are processed to extract features which are then used to classify healthy (normal), suspicious (probably defective) and non-decidable cases. Decisions raised by two independent classifiers may be individually treated, or if desired and data related to both modalities are available, those decisions can be combined to keep matters more secure. Even more security can be attained by using more than two modalities and base the final decision on all those potential classifiers. Our current system relies on feature extraction from images for cases (for particular patients). The first step is image preprocessing and segmentation to get rid of useless image pixels and represent the input in a more compact domain, which is hopefully more representative for good classification performance. Next, a particular type of feature extraction, which uses Zernike moments computed on either B/W or gray-scale image segments, is performed. The aim here is to obtain values for indicative markers that signal the presence of spina bifida. Markers differ depending on the image modality being used. Either shape or texture information captured by moments may propose useful features. Finally, SVM is used to train classifiers to be used as decision makers. Our experimental results show that a promising CAD system can be actualized for the specific purpose. On the other hand, the performance of such a system would highly depend on the qualities of image preprocessing, segmentation, feature extraction and comprehensiveness of image data.

  3. Performance characteristics of a self-sealing/self-healing barrier

    Energy Technology Data Exchange (ETDEWEB)

    McGregor, R.G. [Water Technology International Corp., Burlington, Ontario (Canada)]|[Canadian Clean Technology Centre, Burlington, Ontario (Canada); Stegemann, J.A. [Canadian Clean Technology Centre, Burlington, Ontario (Canada)

    1997-12-31

    Environment Canada and the Netherlands Energy Research Foundation are co-developers of a patented Self-Sealing/Self-Healing (SS/SH) Barrier system for containment of wastes which is licensed to Water Technology International Corporation. The SS/SH Barrier is intended for use as either a liner or cover for landfills, contaminated sites, secondary containment areas, etc., in the industrial, chemical, mining and municipal sectors, and also as a barrier to hydraulic flow for the transportation and construction industry. The SS/SH Barrier`s most significant feature is its capability for self-repair in the event of a breach. By contrast, conventional barrier systems, such as clay, geomembrane, or geosynthetic clay liners can not be repaired without laborious excavation and reconstruction. Laboratory investigations have shown that the SS/SH Barrier concept will function with a variety of reactive materials. Self-Sealing/Self-Healing Barriers are cost competitive and consistently exhibit hydraulic conductivities ranging from 10{sup -9} to 10{sup -13} m/s, which decrease with time. These measurements meet or exceed the recommended hydraulic conductivity required by EPA for clay liners (<1x10{sup -9} m/s) used in landfills and hazardous waste sites. Results of mineralogical examination of the seal, diffusion testing, hydraulic conductivity measurement, and durability testing, including wet/dry, freeze/thaw cycling and leachate compatibility are also presented.

  4. Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system

    Science.gov (United States)

    McDannold, Nathan; Zhang, Yongzhi; Power, Chanikarn; Arvanitis, Costas D.; Vykhodtseva, Natalia; Livingstone, Margaret

    2015-05-01

    The physiology of the vasculature in the central nervous system (CNS), which includes the blood-brain barrier (BBB) and other factors, complicates the delivery of most drugs to the brain. Different methods have been used to bypass the BBB, but they have limitations such as being invasive, non-targeted or requiring the formulation of new drugs. Focused ultrasound (FUS), when combined with circulating microbubbles, is a noninvasive method to locally and transiently disrupt the BBB at discrete targets. The method presents new opportunities for the use of drugs and for the study of the brain.

  5. A Kinect based sign language recognition system using spatio-temporal features

    Science.gov (United States)

    Memiş, Abbas; Albayrak, Songül

    2013-12-01

    This paper presents a sign language recognition system that uses spatio-temporal features on RGB video images and depth maps for dynamic gestures of Turkish Sign Language. Proposed system uses motion differences and accumulation approach for temporal gesture analysis. Motion accumulation method, which is an effective method for temporal domain analysis of gestures, produces an accumulated motion image by combining differences of successive video frames. Then, 2D Discrete Cosine Transform (DCT) is applied to accumulated motion images and temporal domain features transformed into spatial domain. These processes are performed on both RGB images and depth maps separately. DCT coefficients that represent sign gestures are picked up via zigzag scanning and feature vectors are generated. In order to recognize sign gestures, K-Nearest Neighbor classifier with Manhattan distance is performed. Performance of the proposed sign language recognition system is evaluated on a sign database that contains 1002 isolated dynamic signs belongs to 111 words of Turkish Sign Language (TSL) in three different categories. Proposed sign language recognition system has promising success rates.

  6. Self-incompatibility systems: barriers to self-fertilization in flowering plants.

    Science.gov (United States)

    Rea, Anne C; Nasrallah, June B

    2008-01-01

    Flowering plants (angiosperms) are the most prevalent and evolutionarily advanced group of plants. Success of these plants is owed to several unique evolutionary adaptations that aid in reproduction: the flower, the closed carpel, double fertilization, and the ultimate products of fertilization, seeds enclosed in the fruit. Angiosperms exhibit a vast array of reproductive strategies, including both asexual and sexual, the latter of which includes both self-fertilization and cross-fertilization. Asexual reproduction and self-fertilization are important reproductive strategies in a variety of situations, such as when mates are scarce or when the environment remains relatively stable. However, reproductive strategies promoting cross-fertilization are critical to angiosperm success, since they contribute to the creation of genetically diverse populations, which increase the probability that at least one individual in a population will survive given changing environmental conditions. The evolution of several physical and genetic barriers to self-fertilization or fertilization among closely related individuals is thus widespread in angiosperms. A major genetic barrier to self-fertilization is self-incompatibility (SI), which allows female reproductive cells to discriminate between "self" and "non-self" pollen, and specifically reject self pollen. Evidence for the importance of SI in angiosperm evolution lies in the highly diverse set of mechanisms used by various angiosperm families for recognition of self pollen tube development and preventing self-fertilization.

  7. Exploiting Fashion Features for Floor Storage Systems in the Shoe Industry

    OpenAIRE

    Antonella Meneghetti

    2013-01-01

    Floor storage systems are used in the shoe industry to store fashion products of seasonal collections of low quantity and high variety. Since space is valuable and order picking must be sped up, stacking of shoeboxes should be optimized. The problem is modelled based on shoe features (model, type, colour, and size) and with the goal of forcing similar boxes into locations close to each other in order to improve workers’ ability to retrieve orders fast. The model is encoded in Constraint Logic...

  8. ARTICLES: Some features of parametric conversion of infrared radiation in a system generating a difference frequency

    Science.gov (United States)

    Galaĭchuk, Yu A.; Strizhevskiĭ, V. L.; Yashkir, Yu N.

    1984-11-01

    A fluctuation theory is developed for the parametric conversion of infrared radiation utilizing four-photon difference frequency generation processes. An analysis is made of some features of optical parametric oscillation in this system allowing for sum frequency generation. Parametric "conversion" of quantum fluctuations to the frequency range of the infrared signal is discussed and it is shown that this effect increases the noise level.

  9. Real-time marker-free motion capture system using blob feature analysis

    Science.gov (United States)

    Park, Chang-Joon; Kim, Sung-Eun; Kim, Hong-Seok; Lee, In-Ho

    2005-02-01

    This paper presents a real-time marker-free motion capture system which can reconstruct 3-dimensional human motions. The virtual character of the proposed system mimics the motion of an actor in real-time. The proposed system captures human motions by using three synchronized CCD cameras and detects the root and end-effectors of an actor such as a head, hands, and feet by exploiting the blob feature analysis. And then, the 3-dimensional positions of end-effectors are restored and tracked by using Kalman filter. At last, the positions of the intermediate joint are reconstructed by using anatomically constrained inverse kinematics algorithm. The proposed system was implemented under general lighting conditions and we confirmed that the proposed system could reconstruct motions of a lot of people wearing various clothes in real-time stably.

  10. Aircraft engine-mounted camera system for long wavelength infrared imaging of in-service thermal barrier coated turbine blades

    Science.gov (United States)

    Markham, James; Cosgrove, Joseph; Scire, James; Haldeman, Charles; Agoos, Ian

    2014-12-01

    This paper announces the implementation of a long wavelength infrared camera to obtain high-speed thermal images of an aircraft engine's in-service thermal barrier coated turbine blades. Long wavelength thermal images were captured of first-stage blades. The achieved temporal and spatial resolutions allowed for the identification of cooling-hole locations. The software and synchronization components of the system allowed for the selection of any blade on the turbine wheel, with tuning capability to image from leading edge to trailing edge. Its first application delivered calibrated thermal images as a function of turbine rotational speed at both steady state conditions and during engine transients. In advance of presenting these data for the purpose of understanding engine operation, this paper focuses on the components of the system, verification of high-speed synchronized operation, and the integration of the system with the commercial jet engine test bed.

  11. A simulation of remote sensor systems and data processing algorithms for spectral feature classification

    Science.gov (United States)

    Arduini, R. F.; Aherron, R. M.; Samms, R. W.

    1984-01-01

    A computational model of the deterministic and stochastic processes involved in multispectral remote sensing was designed to evaluate the performance of sensor systems and data processing algorithms for spectral feature classification. Accuracy in distinguishing between categories of surfaces or between specific types is developed as a means to compare sensor systems and data processing algorithms. The model allows studies to be made of the effects of variability of the atmosphere and of surface reflectance, as well as the effects of channel selection and sensor noise. Examples of these effects are shown.

  12. Feature extraction from time domain acoustic signatures of weapons systems fire

    Science.gov (United States)

    Yang, Christine; Goldman, Geoffrey H.

    2014-06-01

    The U.S. Army is interested in developing algorithms to classify weapons systems fire based on their acoustic signatures. To support this effort, an algorithm was developed to extract features from acoustic signatures of weapons systems fire and applied to over 1300 signatures. The algorithm filtered the data using standard techniques then estimated the amplitude and time of the first five peaks and troughs and the location of the zero crossing in the waveform. The results were stored in Excel spreadsheets. The results are being used to develop and test acoustic classifier algorithms.

  13. A global vision system: using hue thresholds to exact feature and recognize

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The fast-paced nature of robotic soccer necessitates real-time sensing coupled with quick behaving and decision-making. In the field with real robots, it is important to well perceive the location of ball, team ro bots and opponent robots through the vision system in real time. In this paper the architecture of global vision system of our small size robotic team and the process of object recognition is described. According to the study on color distribution in different color space and quantitative investigation, a method which uses H(Hue) thresholds as the major thresholds to feature exact and recognize object in real-time is presented.

  14. Geophysical characterization of subsurface barriers

    Energy Technology Data Exchange (ETDEWEB)

    Borns, D.J.

    1995-08-01

    An option for controlling contaminant migration from plumes and buried waste sites is to construct a subsurface barrier of a low-permeability material. The successful application of subsurface barriers requires processes to verify the emplacement and effectiveness of barrier and to monitor the performance of a barrier after emplacement. Non destructive and remote sensing techniques, such as geophysical methods, are possible technologies to address these needs. The changes in mechanical, hydrologic and chemical properties associated with the emplacement of an engineered barrier will affect geophysical properties such a seismic velocity, electrical conductivity, and dielectric constant. Also, the barrier, once emplaced and interacting with the in situ geologic system, may affect the paths along which electrical current flows in the subsurface. These changes in properties and processes facilitate the detection and monitoring of the barrier. The approaches to characterizing and monitoring engineered barriers can be divided between (1) methods that directly image the barrier using the contrasts in physical properties between the barrier and the host soil or rock and (2) methods that reflect flow processes around or through the barrier. For example, seismic methods that delineate the changes in density and stiffness associated with the barrier represents a direct imaging method. Electrical self potential methods and flow probes based on heat flow methods represent techniques that can delineate the flow path or flow processes around and through a barrier.

  15. A system-level pathway-phenotype association analysis using synthetic feature random forest.

    Science.gov (United States)

    Pan, Qinxin; Hu, Ting; Malley, James D; Andrew, Angeline S; Karagas, Margaret R; Moore, Jason H

    2014-04-01

    As the cost of genome-wide genotyping decreases, the number of genome-wide association studies (GWAS) has increased considerably. However, the transition from GWAS findings to the underlying biology of various phenotypes remains challenging. As a result, due to its system-level interpretability, pathway analysis has become a popular tool for gaining insights on the underlying biology from high-throughput genetic association data. In pathway analyses, gene sets representing particular biological processes are tested for significant associations with a given phenotype. Most existing pathway analysis approaches rely on single-marker statistics and assume that pathways are independent of each other. As biological systems are driven by complex biomolecular interactions, embracing the complex relationships between single-nucleotide polymorphisms (SNPs) and pathways needs to be addressed. To incorporate the complexity of gene-gene interactions and pathway-pathway relationships, we propose a system-level pathway analysis approach, synthetic feature random forest (SF-RF), which is designed to detect pathway-phenotype associations without making assumptions about the relationships among SNPs or pathways. In our approach, the genotypes of SNPs in a particular pathway are aggregated into a synthetic feature representing that pathway via Random Forest (RF). Multiple synthetic features are analyzed using RF simultaneously and the significance of a synthetic feature indicates the significance of the corresponding pathway. We further complement SF-RF with pathway-based Statistical Epistasis Network (SEN) analysis that evaluates interactions among pathways. By investigating the pathway SEN, we hope to gain additional insights into the genetic mechanisms contributing to the pathway-phenotype association. We apply SF-RF to a population-based genetic study of bladder cancer and further investigate the mechanisms that help explain the pathway-phenotype associations using SEN. The

  16. Histogram of Intensity Feature Extraction for Automatic Plastic Bottle Recycling System Using Machine Vision

    Directory of Open Access Journals (Sweden)

    Suzaimah Ramli

    2008-01-01

    Full Text Available Currently, many recycling activities adopt manual sorting for plastic recycling that relies on plant personnel who visually identify and pick plastic bottles as they travel along the conveyor belt. These bottles are then sorted into the respective containers. Manual sorting may not be a suitable option for recycling facilities of high throughput. It has also been noted that the high turnover among sorting line workers had caused difficulties in achieving consistency in the plastic separation process. As a result, an intelligent system for automated sorting is greatly needed to replace manual sorting system. The core components of machine vision for this intelligent sorting system is the image recognition and classification. In this research, the overall plastic bottle sorting system is described. Additionally, the feature extraction algorithm used is discussed in detail since it is the core component of the overall system that determines the success rate. The performance of the proposed feature extractions were evaluated in terms of classification accuracy and result obtained showed an accuracy of more than 80%.

  17. Small UAS-Based Wind Feature Identification System Part 1: Integration and Validation

    Directory of Open Access Journals (Sweden)

    Leopoldo Rodriguez Salazar

    2016-12-01

    Full Text Available This paper presents a system for identification of wind features, such as gusts and wind shear. These are of particular interest in the context of energy-efficient navigation of Small Unmanned Aerial Systems (UAS. The proposed system generates real-time wind vector estimates and a novel algorithm to generate wind field predictions. Estimations are based on the integration of an off-the-shelf navigation system and airspeed readings in a so-called direct approach. Wind predictions use atmospheric models to characterize the wind field with different statistical analyses. During the prediction stage, the system is able to incorporate, in a big-data approach, wind measurements from previous flights in order to enhance the approximations. Wind estimates are classified and fitted into a Weibull probability density function. A Genetic Algorithm (GA is utilized to determine the shaping and scale parameters of the distribution, which are employed to determine the most probable wind speed at a certain position. The system uses this information to characterize a wind shear or a discrete gust and also utilizes a Gaussian Process regression to characterize continuous gusts. The knowledge of the wind features is crucial for computing energy-efficient trajectories with low cost and payload. Therefore, the system provides a solution that does not require any additional sensors. The system architecture presents a modular decentralized approach, in which the main parts of the system are separated in modules and the exchange of information is managed by a communication handler to enhance upgradeability and maintainability. Validation is done providing preliminary results of both simulations and Software-In-The-Loop testing. Telemetry data collected from real flights, performed in the Seville Metropolitan Area in Andalusia (Spain, was used for testing. Results show that wind estimation and predictions can be calculated at 1 Hz and a wind map can be updated at 0.4 Hz

  18. Small UAS-Based Wind Feature Identification System Part 1: Integration and Validation

    Science.gov (United States)

    Rodriguez Salazar, Leopoldo; Cobano, Jose A.; Ollero, Anibal

    2016-01-01

    This paper presents a system for identification of wind features, such as gusts and wind shear. These are of particular interest in the context of energy-efficient navigation of Small Unmanned Aerial Systems (UAS). The proposed system generates real-time wind vector estimates and a novel algorithm to generate wind field predictions. Estimations are based on the integration of an off-the-shelf navigation system and airspeed readings in a so-called direct approach. Wind predictions use atmospheric models to characterize the wind field with different statistical analyses. During the prediction stage, the system is able to incorporate, in a big-data approach, wind measurements from previous flights in order to enhance the approximations. Wind estimates are classified and fitted into a Weibull probability density function. A Genetic Algorithm (GA) is utilized to determine the shaping and scale parameters of the distribution, which are employed to determine the most probable wind speed at a certain position. The system uses this information to characterize a wind shear or a discrete gust and also utilizes a Gaussian Process regression to characterize continuous gusts. The knowledge of the wind features is crucial for computing energy-efficient trajectories with low cost and payload. Therefore, the system provides a solution that does not require any additional sensors. The system architecture presents a modular decentralized approach, in which the main parts of the system are separated in modules and the exchange of information is managed by a communication handler to enhance upgradeability and maintainability. Validation is done providing preliminary results of both simulations and Software-In-The-Loop testing. Telemetry data collected from real flights, performed in the Seville Metropolitan Area in Andalusia (Spain), was used for testing. Results show that wind estimation and predictions can be calculated at 1 Hz and a wind map can be updated at 0.4 Hz. Predictions

  19. Rule Based System for Enhancing Recall for Feature Mining from Short Sentences in Customer Review Documents

    Directory of Open Access Journals (Sweden)

    Tanvir Ahmad

    2012-06-01

    Full Text Available This paper discovers rules for enhancing the recall values of sentences containing opinions from customer review documents. It does so by mining the features and opinion from different blogs, news site, and review sites. With the advent of numerous web sites which are posting online reviews and opinion there has been exponential growth of user generated contents. Since almost all the contents are stored in unstructured or semi-structured format, mining of features and opinions from it has become a challenging task. The paper extracts features and thereby opinions sentences using semantic and linguistic analysis of text documents. The polarity of the extracted opinions is established using numeric score values obtained through Senti- WordNet. The system shows that normal rules discovered earlier are not sufficient to improve recall values as some of the opinions does not contain sentences which are linguistically correct but they express the main idea what the writer wants to convey about his opinion on a particular product. Our experiment uses a method which first identifies short sentences and then uses rules which can be applied on those sentences so that the recall values are enhanced. The paper also applies rules on sentences which are linguistically and syntactically incorrect. The efficacy of the system is established through experimentation over customer reviews on four different models of digital camera, and iPhone.

  20. Bilateral sudden sensorineural hearing loss as a presenting feature of systemic lupus erythematosus

    Science.gov (United States)

    Chawki, Sylvain; Aouizerate, Jessie; Trad, Selim; Prinseau, Jacques; Hanslik, Thomas

    2016-01-01

    Abstract Introduction: Sudden sensorineural hearing loss is an unusual presenting clinical feature of systemic lupus erythematosus. Case report: We report the case of a young woman who was admitted to hospital for sudden sensorineural hearing loss and hemophagocytic syndrome which was attributed to systemic lupus erythematosus on the basis of specific renal involvement, thrombocytopenia, and consistent autoantibodies. Favorable outcome was obtained on high-dose corticosteroids, and the hearing fully recovered. Discussion: Sudden sensorineural hearing loss in systemic lupus erythematosus is seemingly more frequently associated with severe systemic involvement and antiphospholipid antibodies may be present. Although management remains empirical, the high risk of permanent hearing impairment seems to justify emergency treatment with high-dose corticosteroids. When the clinical and laboratory criteria of antiphospholipid syndrome are met, antiplatelets agents or anticoagulation therapy shall be considered. PMID:27603334

  1. Assessing the performance of a permeable reactive barrier-aquifer system using a dual-domain solute transport model

    Science.gov (United States)

    Chen, Jui-Sheng; Hsu, Shao-Yiu; Li, Ming-Hsu; Liu, Chen-Wuing

    2016-12-01

    Transport behavior through a permeable reactive barrier (PRB)-aquifer system is complicated because of the different physical and chemical properties of the PRB and the aquifer. Dual-domain solute transport models are efficient tools for better understanding the various processes and mechanisms of reactive solute transport through a PRB-aquifer system. This study develops a dual-domain analytical model to assess the physical and chemical processes of two-dimensional reactive solute transport through a PRB-aquifer system. The dispersion processes of a dual-domain system on the solute transport are investigated. The results show that the dispersion parameters in a dual-domain system synchronously govern the dynamic shape of the contaminant plume. The low longitudinal and transverse dispersion coefficients of a dual-domain system may restrict the spreading of the plume and elevate the plume's concentration level. The derived analytical solution is applied to explore how the different reactive transport processes affect the performance of a PRB-aquifer system. The results show that the first-order decay rate constant of the PRB has a critical effect on the performance of the PRB-aquifer system, whereas the effects of the physical dispersion properties on PRB performance are less significant.

  2. Deep inelastic scattering near the Coulomb barrier

    Energy Technology Data Exchange (ETDEWEB)

    Gehring, J.; Back, B.; Chan, K. [and others

    1995-08-01

    Deep inelastic scattering was recently observed in heavy ion reactions at incident energies near and below the Coulomb barrier. Traditional models of this process are based on frictional forces and are designed to predict the features of deep inelastic processes at energies above the barrier. They cannot be applied at energies below the barrier where the nuclear overlap is small and friction is negligible. The presence of deep inelastic scattering at these energies requires a different explanation. The first observation of deep inelastic scattering near the barrier was in the systems {sup 124,112}Sn + {sup 58,64}Ni by Wolfs et al. We previously extended these measurements to the system {sup 136}Xe + {sup 64}Ni and currently measured the system {sup 124}Xe + {sup 58}Ni. We obtained better statistics, better mass and energy resolution, and more complete angular coverage in the Xe + Ni measurements. The cross sections and angular distributions are similar in all of the Sn + Ni and Xe + Ni systems. The data are currently being analyzed and compared with new theoretical calculations. They will be part of the thesis of J. Gehring.

  3. Central nervous system tumors with ependymal features: a broadened spectrum of primarily ependymal differentiation?

    Science.gov (United States)

    Lehman, Norman L

    2008-03-01

    Ependymomas are well-characterized central nervous system (CNS) tumors that occur most often in children and young adults. Several other CNS tumor entities, including astroblastoma, chordoid glioma, papillary tumor of the pineal region, angiocentric glioma, and pilomyxoid astrocytoma, variably display histopathologic features of ependymal differentiation. The ependymal differentiation in some of these tumors is generally accepted, whereas in others, it is controversial. This article briefly reviews ependymal cell development and conventional ependymomas, the pathologic findings and clinical behavior of tumors with variable ependymal features, and the rationales for their inclusion with ependymomas or exclusion from a larger family of ependymal tumors. These issues are addressed in the context of early morphologic insights of Bailey and Cushing, Friede, and others; contemporary oncologic concepts; and recent relevant molecular and tumor stem cell studies.

  4. Modeling and Detecting Feature Interactions among Integrated Services of Home Network Systems

    Science.gov (United States)

    Igaki, Hiroshi; Nakamura, Masahide

    This paper presents a framework for formalizing and detecting feature interactions (FIs) in the emerging smart home domain. We first establish a model of home network system (HNS), where every networked appliance (or the HNS environment) is characterized as an object consisting of properties and methods. Then, every HNS service is defined as a sequence of method invocations of the appliances. Within the model, we next formalize two kinds of FIs: (a) appliance interactions and (b) environment interactions. An appliance interaction occurs when two method invocations conflict on the same appliance, whereas an environment interaction arises when two method invocations conflict indirectly via the environment. Finally, we propose offline and online methods that detect FIs before service deployment and during execution, respectively. Through a case study with seven practical services, it is shown that the proposed framework is generic enough to capture feature interactions in HNS integrated services. We also discuss several FI resolution schemes within the proposed framework.

  5. Development Status and Performance Comparisons of Environmental Barrier Coating Systems for SiCSiC Ceramic Matrix Composites

    Science.gov (United States)

    Zhu, Dongming; Harder, Bryan

    2016-01-01

    Environmental barrier coatings (EBC) and SiCSiC ceramic matrix composites (CMCs) will play a crucial role in future aircraft turbine engine systems, because of their ability to significantly increase engine operating temperatures, reduce engine weight and cooling requirements. This paper presents current NASA EBC-CMC development emphases including: the coating composition and processing improvements, laser high heat flux-thermal gradient thermo-mechanical fatigue - environmental testing methodology development, and property evaluations for next generation EBC-CMC systems. EBCs processed with various deposition techniques including Plasma Spray, Electron Beam - Physical Vapor Deposition, and Plasma Spray Physical Vapor Deposition (PS-PVD) will be particularly discussed. The testing results and demonstrations of advanced EBCs-CMCs in complex simulated engine thermal gradient cyclic fatigue, oxidizing-steam and CMAS environments will help provide insights into the coating development strategies to meet long-term engine component durability goals.

  6. Perceived barriers of heart failure nurses and cardiologists in using clinical decision support systems in the treatment of heart failure patients

    Science.gov (United States)

    2013-01-01

    Background Clinical Decision Support Systems (CDSSs) can support guideline adherence in heart failure (HF) patients. However, the use of CDSSs is limited and barriers in working with CDSSs have been described as a major obstacle. It is unknown if barriers to CDSSs are present and differ between HF nurses and cardiologists. Therefore the aims of this study are; 1. Explore the type and number of perceived barriers of HF nurses and cardiologists to use a CDSS in the treatment of HF patients. 2. Explore possible differences in perceived barriers between two groups. 3. Assess the relevance and influence of knowledge management (KM) on Responsibility/Trust (R&T) and Barriers/Threats (B&T). Methods A questionnaire was developed including; B&T, R&T, and KM. For analyses, descriptive techniques, 2-tailed Pearson correlation tests, and multiple regression analyses were performed. Results The response- rate of 220 questionnaires was 74%. Barriers were found for cardiologists and HF nurses in all the constructs. Sixty-five percent did not want to be dependent on a CDSS. Nevertheless thirty-six percent of HF nurses and 50% of cardiologists stated that a CDSS can optimize HF medication. No relationship between constructs and age; gender; years of work experience; general computer experience and email/internet were observed. In the group of HF nurses a positive correlation (r .33, PKM was associated with the constructs B&T (B=.55, P=barriers in working with a CDSS in all of the examined constructs. KM has a strong positive correlation with perceived barriers, indicating that increasing knowledge about CDSSs can decrease their barriers. PMID:23622342

  7. Face Recognition for Access Control Systems Combining Image-Difference Features Based on a Probabilistic Model

    Science.gov (United States)

    Miwa, Shotaro; Kage, Hiroshi; Hirai, Takashi; Sumi, Kazuhiko

    We propose a probabilistic face recognition algorithm for Access Control System(ACS)s. Comparing with existing ACSs using low cost IC-cards, face recognition has advantages in usability and security that it doesn't require people to hold cards over scanners and doesn't accept imposters with authorized cards. Therefore face recognition attracts more interests in security markets than IC-cards. But in security markets where low cost ACSs exist, price competition is important, and there is a limitation on the quality of available cameras and image control. Therefore ACSs using face recognition are required to handle much lower quality images, such as defocused and poor gain-controlled images than high security systems, such as immigration control. To tackle with such image quality problems we developed a face recognition algorithm based on a probabilistic model which combines a variety of image-difference features trained by Real AdaBoost with their prior probability distributions. It enables to evaluate and utilize only reliable features among trained ones during each authentication, and achieve high recognition performance rates. The field evaluation using a pseudo Access Control System installed in our office shows that the proposed system achieves a constant high recognition performance rate independent on face image qualities, that is about four times lower EER (Equal Error Rate) under a variety of image conditions than one without any prior probability distributions. On the other hand using image difference features without any prior probabilities are sensitive to image qualities. We also evaluated PCA, and it has worse, but constant performance rates because of its general optimization on overall data. Comparing with PCA, Real AdaBoost without any prior distribution performs twice better under good image conditions, but degrades to a performance as good as PCA under poor image conditions.

  8. The intestinal barrier in irritable bowel syndrome: subtype-specific effects of the systemic compartment in an in vitro model.

    Directory of Open Access Journals (Sweden)

    Samefko Ludidi

    Full Text Available Irritable bowel syndrome (IBS is a disorder with multifactorial pathophysiology. Intestinal barrier may be altered, especially in diarrhea-predominant IBS (IBS-D. Several mediators may contribute to increased intestinal permeability in IBS.We aimed to assess effects of tryptase and LPS on in vitro permeability using a 3-dimensional cell model after basolateral cell exposure. Furthermore, we assessed the extent to which these mediators in IBS plasma play a role in intestinal barrier function.Caco-2 cells were grown in extracellular matrix to develop into polarized spheroids and were exposed to tryptase (10 - 50 mU, LPS (1 - 50 ng/mL and two-fold diluted plasma samples of 7 patients with IBS-D, 7 with constipation-predominant IBS (IBS-C and 7 healthy controls (HC. Barrier function was assessed by the flux of FITC-dextran (FD4 using live cell imaging. Furthermore, plasma tryptase and LPS were determined.Tryptase (20 and 50 mU and LPS (6.25 - 50 ng/mL significantly increased Caco-2 permeability versus control (all P< 0.05. Plasma of IBS-D only showed significantly elevated median tryptase concentrations (7.1 [3.9 - 11.0] vs. 4.2 [2.2 - 7.0] vs. 4.2 [2.5 - 5.9] μg/mL; P<0.05 and LPS concentrations (3.65 [3.00 - 6.10] vs. 3.10 [2.60-3.80] vs. 2.65 [2.40 - 3.40] EU/ml; P< 0.05 vs. IBS-C and HC. Also, plasma of IBS-D increased Caco-2 permeability versus HC (0.14450 ± 0.00472 vs. 0.00021 ± 0.00003; P < 0.001, which was attenuated by selective inhibition of tryptase and LPS (P< 0.05.Basolateral exposure of spheroids to plasma of IBS-D patients resulted in a significantly increased FD4 permeation, which was partially abolished by selective inhibition of tryptase and LPS. These findings point to a role of systemic tryptase and LPS in the epithelial barrier alterations observed in patients with IBS-D.

  9. Clinical features of multiple myeloma invasion of the central nervous system in Chinese patients

    Institute of Scientific and Technical Information of China (English)

    QU Xiao-yan; FU Wei-jun; XI Hao; ZHOU Fan; WEI Wei; HOU Jian

    2010-01-01

    Background Although neurologic manifestations often complicate the course of patients with multiple myeloma, direct central nervous system invasion is rare. This study explored the neurologic symptoms, signs, clinical features, therapy and prognosis of Chinese patients with central nervous system myeloma invasion.Methods The diagnosis, therapy and prognosis were analyzed retrospectively in 11 Chinese multiple myeloma patients with central nervous system infiltration from a total of 625 patients who have been treated at Changzheng Hospital (Shanghai, China) between January 1993 and May 2009. Survival curve was constructed with the use of Kaplan-Meier estimates.Results There were 11 patients with central nervous system involvement from 625 multiple myeloma patients. The occurrence rate was 1.8%. Ten of the 11 patients had other extramedullary diseases. Symptoms included cerebral symptoms, cranial nerve palsies, and spinal cord or spinal nerve roots symptoms.Cerebrospinal fluid was abnormal in 7 patients, usually exhibiting pleocytosis and elevated protein content, plus positive cytologic findings. Specific magnetic resonance imaging findings suggestive of central nervous system invasion were found in 9 patients. After a median follow-up of 19 months, 3 patients were alive. The median overall survival for all patients was 23 months, while the median overall survival for patients after central nervous system invasion was merely 6 months.Conclusions It is exceedingly rare for there to be central nervous system infiltration in multiple myeloma patients. When it occurs, the prognosis is extremely poor despite the use of aggressive local and systemic treatment including stem cell transplantation.

  10. Features of applying systems approach for evaluating the reliability of cryogenic systems for special purposes

    Directory of Open Access Journals (Sweden)

    E. D. Chertov

    2016-01-01

    Full Text Available Summary. The analysis of cryogenic installations confirms objective regularity of increase in amount of the tasks solved by systems of a special purpose. One of the most important directions of development of a cryogenics is creation of installations for air separation product receipt, namely oxygen and nitrogen. Modern aviation complexes require use of these gases in large numbers as in gaseous, and in the liquid state. The onboard gas systems applied in aircraft of the Russian Federation are subdivided on: oxygen system; air (nitric system; system of neutral gas; fire-proof system. Technological schemes ADI are in many respects determined by pressure of compressed air or, in a general sense, a refrigerating cycle. For the majority ADI a working body of a refrigerating cycle the divided air is, that is technological and refrigerating cycles in installation are integrated. By this principle differentiate installations: low pressure; average and high pressure; with detander; with preliminary chilling. There is also insignificant number of the ADI types in which refrigerating and technological cycles are separated. These are installations with external chilling. For the solution of tasks of control of technical condition of the BRV hardware in real time and estimates of indicators of reliability it is offered to use multi-agent technologies. Multi-agent approach is the most acceptable for creation of SPPR for reliability assessment as allows: to redistribute processing of information on elements of system that leads to increase in overall performance; to solve a problem of accumulating, storage and recycling of knowledge that will allow to increase significantly efficiency of the solution of tasks of an assessment of reliability; to considerably reduce intervention of the person in process of functioning of system that will save time of the person of the making decision (PMD and will not demand from it special skills of work with it.

  11. Combining Self-organizing Feature Map with Support Vector Regression Based on Expert System

    Institute of Scientific and Technical Information of China (English)

    WANGLing; MUZhi-Chun; GUOHui

    2005-01-01

    A new approach is proposed to model nonlinear dynamic systems by combining SOM(self-organizing feature map) with support vector regression (SVR) based on expert system. The whole system has a two-stage neural network architecture. In the first stage SOM is used as a clustering algorithm to partition the whole input space into several disjointed regions. A hierarchical architecture is adopted in the partition to avoid the problem of predetermining the number of partitioned regions. Then, in the second stage, multiple SVR, also called SVR experts, that best fit each partitioned region by the combination of different kernel function of SVR and promote the configuration and tuning of SVR. Finally, to apply this new approach to time-series prediction problems based on the Mackey-Glass differential equation and Santa Fe data, the results show that SVR experts has effective improvement in the generalization performance in comparison with the single SVR model.

  12. Hitachi M-620, M-630, and M-640 computer systems: the technology and features

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, Y. (Hitachi, Ltd. Tokyo (Japan))

    1990-10-01

    Several hardware technologies of HITACHI M-620, M-630, and M-640 computer systems are outlined. Every system is featured by the same architecture as the high-end M-680 series processors for facilitating departmental distributed processing, small high-performance devices enhanced with the most modern LSI chips based on advanced semiconductor technologies, and greatly improved expandability, reliability and operability. As hardwares of M-620 and M-630, the 1.3 {mu}m CMOS VLSI chip with 52,000 gates, such several processors as an input-output one (IOP) and service one (SVP), integrated network controller, magnetic disk driver, and cartridge tape unit are outlined. As hardwares of M-640, four models of LSI processors based on an emitter coupled logic (ECL), optical channel system between the CPU and peripherals, 1,260-5,040 Mbyte disk driver, and 256 Mbyte semiconductor storage device are outlined. 6 refs., 6 figs., 6 tabs.

  13. Texture based feature extraction methods for content based medical image retrieval systems.

    Science.gov (United States)

    Ergen, Burhan; Baykara, Muhammet

    2014-01-01

    The developments of content based image retrieval (CBIR) systems used for image archiving are continued and one of the important research topics. Although some studies have been presented general image achieving, proposed CBIR systems for archiving of medical images are not very efficient. In presented study, it is examined the retrieval efficiency rate of spatial methods used for feature extraction for medical image retrieval systems. The investigated algorithms in this study depend on gray level co-occurrence matrix (GLCM), gray level run length matrix (GLRLM), and Gabor wavelet accepted as spatial methods. In the experiments, the database is built including hundreds of medical images such as brain, lung, sinus, and bone. The results obtained in this study shows that queries based on statistics obtained from GLCM are satisfied. However, it is observed that Gabor Wavelet has been the most effective and accurate method.

  14. Load rate dependence of the mechanical properties of thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Zotov, Nikolay; Eggeler, Gunther [Institut fuer Werkstoffe, Ruhr Universitaet Bochum, 44780 Bochum (Germany); Bartsch, Marion [Institut fuer Werkstoff-Forschung, DLR Koeln, 51147 Koeln (Germany)

    2009-07-01

    Thermal barrier coatings (TBC), composed of yttrium-stabilized zirconia (YSZ) ceramic top coat (TC) and intermetallic NiCoCrAlY bond coat (BC) are commonly used as protective coatings of Ni-based high temperature gas engine components. Nanoindentation techniques are increasingly applied for determining the TBC mechanical properties on a nanometre scale. However, little is known about the load-rate dependence of the mechanical properties, which is important for better understanding of cyclic thermal fatigue experiments. Nanoindentations with different load rates omega were performed on polished cross-sections of TBC, deposited by EB-PVD on IN625 substrates (S), using a XP Nanoindenter (MTS) equipped with Berkovich diamond tip. The Young's modulus (E) of the TC is independent of omega, while E for the BC and the S decreases with omega. The hardness (H) of the TC and the BC increases, while H for the S decreases with omega. From the dependence of H on omega, creep power-law exponents c = 0.24(11) and c = 0.023(6) for the TC and the BC were determined. For all TBC components, a decrease with omega of the power-law exponents n and m, describing the loading and unloading nanoindentation curves, is observed.

  15. Blood-Brain Barrier Disruption and Oxidative Stress in Guinea Pig after Systemic Exposure to Modified Cell-Free Hemoglobin

    Science.gov (United States)

    Butt, Omer I.; Buehler, Paul W.; D'Agnillo, Felice

    2011-01-01

    Systemic exposure to cell-free hemoglobin (Hb) or its breakdown products after hemolysis or with the use of Hb-based oxygen therapeutics may alter the function and integrity of the blood-brain barrier. Using a guinea pig exchange transfusion model, we investigated the effect of a polymerized cell-free Hb (HbG) on the expression of endothelial tight junction proteins (zonula occludens 1, claudin-5, and occludin), astrocyte activation, IgG extravasation, heme oxygenase (HO), iron deposition, oxidative end products (4-hydroxynonenal adducts and 8-hydroxydeoxyguanosine), and apoptosis (cleaved caspase 3). Reduced zonula occludens 1 expression was observed after HbG transfusion as evidenced by Western blot and confocal microscopy. Claudin-5 distribution was altered in small- to medium-sized vessels. However, total expression of claudin-5 and occludin remained unchanged except for a notable increase in occludin 72 hours after HbG transfusion. HbG-transfused animals also showed increased astrocytic glial fibrillary acidic protein expression and IgG extravasation after 72 hours. Increased HO activity and HO-1 expression with prominent enhancement of HO-1 immunoreactivity in CD163-expressing perivascular cells and infiltrating monocytes/macrophages were also observed. Consistent with oxidative stress, HbG increased iron deposition, 4-hydroxynonenal and 8-hydroxydeoxyguanosine immunoreactivity, and cleaved caspase-3 expression. Systemic exposure to an extracellular Hb triggers blood-brain barrier disruption and oxidative stress, which may have important implications for the use of Hb-based therapeutics and may provide indirect insight on the central nervous system vasculopathies associated with excessive hemolysis. PMID:21356382

  16. Aplastic anemia as a feature of systemic lupus erythematosus: a case report and literature review.

    Science.gov (United States)

    Chalayer, Émilie; Ffrench, Martine; Cathébras, Pascal

    2015-06-01

    Peripheral cytopenias are common in systemic lupus erythematosus, but bone marrow involvement is rarely reported. Aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and characterized by an empty bone marrow. This rare but serious disease has been described as an unusual manifestation of systemic lupus erythematosus. We reviewed the 25 cases published in the English language literature and discuss the clinical presentation, outcome, treatment, and pathophysiology of aplastic anemia as a complication of systemic lupus erythematosus. We report here the first case of aplastic anemia associated with systemic lupus erythematosus treated with an allogeneic hematopoietic stem cell transplant. Over one half of patients received concomitantly the diagnoses of systemic lupus erythematosus and aplastic anemia. No clinical or histological features can distinguish primary aplastic anemia from aplastic anemia occurring in systemic lupus erythematosus patients. The overall mortality is about 15% and corticosteroid-based therapy alone or in combination with other immunomodulatory drugs can restore bone marrow function. Systemic lupus erythematosus may be complicated by bone marrow involvement. The diagnosis of peripheral cytopenias should be confirmed by bone marrow aspiration. All these patients should receive cortisone as a first treatment. Plasma exchanges seem to have some efficacy. Other different immunomodulatory therapies were used with variable results.

  17. Exploiting Fashion Features for Floor Storage Systems in the Shoe Industry

    Directory of Open Access Journals (Sweden)

    Antonella Meneghetti

    2013-08-01

    Full Text Available Floor storage systems are used in the shoe industry to store fashion products of seasonal collections of low quantity and high variety. Since space is valuable and order picking must be sped up, stacking of shoeboxes should be optimized. The problem is modelled based on shoe features (model, type, colour, and size and with the goal of forcing similar boxes into locations close to each other in order to improve workers’ ability to retrieve orders fast. The model is encoded in Constraint Logic Programming and solved comparing different strategies, also using Large Neighbourhood Search. Simulation experiments are run to evaluate how the stacking model affects picking performance.

  18. FAULT TREE ANALYSIS FEATURES IN INDUSTRIAL SYSTEMS SAFETY ASSESSMENT: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Roland Iosif MORARU

    2012-05-01

    Full Text Available Fault tree analysis is useful both in designing new products/services or in dealing with identified problems in existing ones. In the quality planning process, the analysis can be used to optimize process features and goals and to design for critical factors and human error. As part of safety process improvement, as it is emphasized in the present paper, it can be used to help identify root causes of undesired events such as occupational injuries and illnesses. A case study of application in industrial safety systems illustrates the aim, principle and structure of the technique, allowing better prevention measures selection and implementation.

  19. Features of surface enhanced Raman scattering in the systems with «hot spots»

    Directory of Open Access Journals (Sweden)

    Solovyeva E.V.

    2017-01-01

    Full Text Available In this work we demonstrate the features of SERS on the substrates with «hot spots» on the example of system «diaminostilbene - colloidal silver». We found that «hot spots» forming on aggregated nanoparticles exist on the metal substrates only at low concentration of ligand. This effect caused by the gradual filling of first monolayer by adsorbate molecules. Significantly higher enhancement factor is obtained for substrates with «hot spots», for which the participation of resonance processes in the formation of SERS signal is revealed also.

  20. Features of surface enhanced Raman scattering in the systems with «hot spots»

    Science.gov (United States)

    Solovyeva, E. V.; Khazieva, D. A.; Denisova, A. S.

    2016-12-01

    In this work we demonstrate the features of SERS on the substrates with «hot spots» on the example of system «diaminostilbene - colloidal silver». We found that «hot spots» forming on aggregated nanoparticles exist on the metal substrates only at low concentration of ligand. This effect caused by the gradual filling of first monolayer by adsorbate molecules. Significantly higher enhancement factor is obtained for substrates with «hot spots», for which the participation of resonance processes in the formation of SERS signal is revealed also.

  1. Supervised pixel classification using a feature space derived from an artificial visual system

    Science.gov (United States)

    Baxter, Lisa C.; Coggins, James M.

    1991-01-01

    Image segmentation involves labelling pixels according to their membership in image regions. This requires the understanding of what a region is. Using supervised pixel classification, the paper investigates how groups of pixels labelled manually according to perceived image semantics map onto the feature space created by an Artificial Visual System. Multiscale structure of regions are investigated and it is shown that pixels form clusters based on their geometric roles in the image intensity function, not by image semantics. A tentative abstract definition of a 'region' is proposed based on this behavior.

  2. Testing and monitoring plan for the permanent isolation surface barrier prototype

    Energy Technology Data Exchange (ETDEWEB)

    Gee, G.W.; Cadwell, L.L.; Freeman, H.D.; Ligotke, M.W.; Link, S.O.; Romine, R.A.; Walters, W.H. Jr.

    1993-06-01

    This document is a testing and monitoring plan for a prototype barrier to be constructed at the Hanford Site in 1993. The prototype barrier is an aboveground structure engineered to demonstrate the basic features of an earthen cover system, designed to permanently isolate waste from the biosphere. These features include multiple layers of soil and rock materials and a low-permeability asphalt sublayer. The surface of the barrier consists of silt loam soil, vegetated with plants. The barrier sides are reinforced with rock or coarse earthen-fill to protect against wind and water erosion. The sublayers inhibit plant and animal intrusion and percolation of water. A series of tests will be conducted on the prototype over the next several years to evaluate barrier performance under extreme climatic conditions.

  3. Genetic Fuzzy System (GFS based wavelet co-occurrence feature selection in mammogram classification for breast cancer diagnosis

    Directory of Open Access Journals (Sweden)

    Meenakshi M. Pawar

    2016-09-01

    Full Text Available Breast cancer is significant health problem diagnosed mostly in women worldwide. Therefore, early detection of breast cancer is performed with the help of digital mammography, which can reduce mortality rate. This paper presents wrapper based feature selection approach for wavelet co-occurrence feature (WCF using Genetic Fuzzy System (GFS in mammogram classification problem. The performance of GFS algorithm is explained using mini-MIAS database. WCF features are obtained from detail wavelet coefficients at each level of decomposition of mammogram image. At first level of decomposition, 18 features are applied to GFS algorithm, which selects 5 features with an average classification success rate of 39.64%. Subsequently, at second level it selects 9 features from 36 features and the classification success rate is improved to 56.75%. For third level, 16 features are selected from 54 features and average success rate is improved to 64.98%. Lastly, at fourth level 72 features are applied to GFS, which selects 16 features and thereby increasing average success rate to 89.47%. Hence, GFS algorithm is the effective way of obtaining optimal set of feature in breast cancer diagnosis.

  4. Dielectric barrier discharges applied for optical spectrometry

    Science.gov (United States)

    Brandt, S.; Schütz, A.; Klute, F. D.; Kratzer, J.; Franzke, J.

    2016-09-01

    The present review reflects the importance of dielectric barrier discharges for optical spectrometric detection in analytical chemistry. In contrast to usual discharges with a direct current the electrodes are separated by at least one dielectric barrier. There are two main features of the dielectric barrier discharges: they can serve as dissociation and excitation devices as well as ionization sources, respectively. This article portrays various application fields of dielectric barrier discharges in analytical chemistry used for elemental and molecular detection with optical spectrometry.

  5. Fingerprint Feature Extraction Based on Macroscopic Curvature

    Institute of Scientific and Technical Information of China (English)

    Zhang Xiong; He Gui-ming; Zhang Yun

    2003-01-01

    In the Automatic Fingerprint Identification System (AFIS), extracting the feature of fingerprint is very important. The local curvature of ridges of fingerprint is irregular, so people have the barrier to effectively extract the fingerprint curve features to describe fingerprint. This article proposes a novel algorithm; it embraces information of few nearby fingerprint ridges to extract a new characteristic which can describe the curvature feature of fingerprint. Experimental results show the algorithm is feasible, and the characteristics extracted by it can clearly show the inner macroscopic curve properties of fingerprint. The result also shows that this kind of characteristic is robust to noise and pollution.

  6. Fingerprint Feature Extraction Based on Macroscopic Curvature

    Institute of Scientific and Technical Information of China (English)

    Zhang; Xiong; He; Gui-Ming; 等

    2003-01-01

    In the Automatic Fingerprint Identification System(AFIS), extracting the feature of fingerprint is very important. The local curvature of ridges of fingerprint is irregular, so people have the barrier to effectively extract the fingerprint curve features to describe fingerprint. This article proposes a novel algorithm; it embraces information of few nearby fingerprint ridges to extract a new characterstic which can describe the curvature feature of fingerprint. Experimental results show the algorithm is feasible, and the characteristics extracted by it can clearly show the inner macroscopic curve properties of fingerprint. The result also shows that this kind of characteristic is robust to noise and pollution.

  7. Amazonian-aged fluvial system and associated ice-related features in Terra Cimmeria, Mars

    Science.gov (United States)

    Adeli, Solmaz; Hauber, Ernst; Kleinhans, Maarten; Le Deit, Laetitia; Platz, Thomas; Fawdon, Peter; Jaumann, Ralf

    2016-10-01

    The Martian climate throughout the Amazonian is widely believed to have been cold and hyper-arid, very similar to the current conditions. However, ubiquitous evidence of aqueous and glacial activity has been recently reported, including channels that can be tens to hundreds of kilometres long, alluvial and fluvial deposits, ice-rich mantles, and glacial and periglacial landforms. Here we study a ∼340 km-long fluvial system located in the Terra Cimmeria region, in the southern mid-latitudes of Mars. The fluvial system is composed of an upstream catchment system with narrow glaciofluvial valleys and remnants of ice-rich deposits. We observe depositional features including fan-shaped deposits, and erosional features such as scour marks and streamlined islands. At the downstream section of this fluvial system is an outflow channel named Kārūn Valles, which displays a unique braided alluvial fan and terminates on the floor of the Ariadnes Colles basin. Our observations point to surface runoff of ice/snow melt as the water source for this fluvial activity. According to our crater size-frequency distribution analysis the entire fluvial system formed during early to middle Amazonian, between ∼ 1.8-0.2+0.2 Ga to 510-40+40 Ma. Hydraulic modelling indicates that the Kārūn Valles and consequently the alluvial fan formation took place in geologically short-term event(s). We conclude that liquid water was present in Terra Cimmeria during the early to middle Amazonian, and that Mars during that time may have undergone several episodic glacial-related events.

  8. Reliability study: digital engineered safety feature actuation system of Korean Standard Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Sudarno [National Nuclear Energy Agency, Batan (Indonesia); Kang, H. G.; Jang, S. C.; Eom, H. S.; Ha, J. J. [KAERI, Taejon (Korea, Republic of)

    2003-04-01

    The usage of digital Instrumentation and Control (I and C) in a nuclear power plant becomes more extensive, including safety related systems. The PSA application of these new designs are very important in order to evaluate their reliability. In particular, Korean Standard Nuclear Power Plants (KSNPPs), typically Ulchin 5 and 6 (UCN 5 and 6) reactor units, adopted the digital safety-critical systems such as Digital Plant Protection System (DPPS) and Digital Engineered Safety Feature Actuation System (DESFAS). In this research, we developed fault tree models for assessing the unavailability of the DESFAS functions. We also performed an analysis of the quantification results. The unavailability results of different DESFAS functions showed that their values are comprised from 5.461E-5 to 3.14E-4. The system unavailability of DESFAS AFAS-1 is estimated as 5.461E-5, which is about 27% less than that of analog system if we consider the difference of human failure probability estimation between both analyses. The results of this study could be utilized in risk-effect analysis of KSNPP. We expect that the safety analysis result will contribute to design feedback.

  9. Benefits and Barriers of Implementation and Utilization of Radio-Frequency Identification (RFID) Systems in Transfusion Medicine.

    Science.gov (United States)

    Coustasse, Alberto; Cunningham, Brian; Deslich, Stacie; Willson, Eric; Meadows, Pamela

    2015-01-01

    Radio-frequency identification (RFID) technology is used by hospital supply chains to track medical products and monitor inventories. Hospitals have also begun incorporating RFID technology as part of their transfusion processes. The purpose of this review was to analyze how healthcare organization supply chains can benefit from the utilization of RFID systems in transfusion service departments. The methodology for this study was a literature review following the steps of a systematic review with a total of 52 sources referenced. RFID technology is used to manage and track blood products from the initial donor phlebotomy to final disposition or product transfusion. RFID-enabled transfusion practices have successfully increased provider productivity and product quality through work-time reduction and error reduction. Findings of this research study suggest that RFID has provided improvements in quality of care and efficiency, while initial costs, security, and privacy appear to be the principal barriers to adoption.

  10. Effect of Residual Stresses and Prediction of Possible Failure Mechanisms on Thermal Barrier Coating System by Finite Element Method

    Science.gov (United States)

    Ranjbar-Far, M.; Absi, J.; Mariaux, G.; Shahidi, S.

    2010-09-01

    This work is focused on the effect of the residual stresses resulting from the coating process and thermal cycling on the failure mechanisms within the thermal barrier coating (TBC) system. To reach this objective, we studied the effect of the substrate preheating and cooling rate on the coating process conditions. A new thermomechanical finite element model (FEM) considering a nonhomogeneous temperature distribution has been developed. In the results, we observed a critical stress corresponding to a low substrate temperature and high cooling rate during spraying of the top-coat material. Moreover, the analysis of the stress distribution after service shows that more critical stresses are obtained in the case where residual stresses are taken into account.

  11. Barriers to control syphilis and HIV vertical transmission in the health care system in the city of Sao Paulo

    Directory of Open Access Journals (Sweden)

    Valdete Maria Ramos

    2014-12-01

    Full Text Available OBJECTIVE: The objective of this study was to identify possible barriers to control vertical transmission of syphilis and HIV through the analysis of the orientation process of pregnant women from prenatal care to the obstetric center at an university hospital in Sao Paulo (Reference and their return (with their exposed babies for follow-up after hospital discharge (counter-reference. METHODS: It is a retrospective cross-sectional study including interviews with healthcare personnel. Pregnant women with syphilis and/or HIV-infection admitted for labor or miscarriage were identified from August 2006 to August 2007. Routine care for mothers and babies were analyzed. RESULTS: 56 pregnant women were identified: 43 were HIV-infected, 11 had syphilis and two were coinfected (syphilis/HIV; 22 health care professionals were interviewed. Prenatal care was identified in 91.1% of these women: 7/11 (63.6% with syphilis; 44/45 (97.8% HIV-infected or coinfected. The reference for delivery was satisfactory for 57.7% of the syphilis-infected women and 97.7% of the HIV-infected ones. The counter-reference was satisfactory for all babies and mothers at hospital discharge, besides the non-adherence to this recommendation. Interviews with health care professionals showed there are better routines for assisting and following-up pregnant women, puerperal women and HIV-infected or exposed babies than for those infected with syphilis. The epidemiological report and surveillance system are also better for HIV-infected patients. CONCLUSION: The difficulties in the reference and counter-reference system of these women and their babies are evident barriers to control the vertical transmission of these infectious diseases.

  12. Running experience with the DELPHI pixel detector reflections on design characteristics and system features

    CERN Document Server

    Heuser, J M

    1999-01-01

    The DELPHI experiment at LEP is the first collider experiment with hybrid pixel detectors contributing to its track reconstruction. The pixel detector has been installed in 1996 with the final DELPHI silicon tracker, an assembly of microstrip, ministrip and pixel detectors optimized for the operation at LEP2. It was completed for the physics period in 1997. The pixel detector comprises 1.2 million detector cells of 330*330 mu m/sup 2/. 152 detector modules are arranged in 4 inclined cone-shaped layers which cover polar angles from 10 degrees to 25 degrees . Experience on the system's features has been gained during three years of operation. The article intends to provide information on positive and critical aspects which might be useful for designers of pixel detector systems in forthcoming experiments. (4 refs).

  13. Enhanced Performance by Time-Frequency-Phase Feature for EEG-Based BCI Systems

    Directory of Open Access Journals (Sweden)

    Baolei Xu

    2014-01-01

    Full Text Available We introduce a new motor parameter imagery paradigm using clench speed and clench force motor imagery. The time-frequency-phase features are extracted from mu rhythm and beta rhythms, and the features are optimized using three process methods: no-scaled feature using “MIFS” feature selection criterion, scaled feature using “MIFS” feature selection criterion, and scaled feature using “mRMR” feature selection criterion. Support vector machines (SVMs and extreme learning machines (ELMs are compared for classification between clench speed and clench force motor imagery using the optimized feature. Our results show that no significant difference in the classification rate between SVMs and ELMs is found. The scaled feature combinations can get higher classification accuracy than the no-scaled feature combinations at significant level of 0.01, and the “mRMR” feature selection criterion can get higher classification rate than the “MIFS” feature selection criterion at significant level of 0.01. The time-frequency-phase feature can improve the classification rate by about 20% more than the time-frequency feature, and the best classification rate between clench speed motor imagery and clench force motor imagery is 92%. In conclusion, the motor parameter imagery paradigm has the potential to increase the direct control commands for BCI control and the time-frequency-phase feature has the ability to improve BCI classification accuracy.

  14. Information schema constructs for defining warehouse databases of genotypes and phenotypes of system manifestation features

    Institute of Scientific and Technical Information of China (English)

    Shahab POURTALEBI‡; Imre HORVÁTH

    2016-01-01

    Our long-term objective is to develop a software toolbox for pre-embodiment design of complex and heterogeneous systems, such as cyber-physical systems. The novelty of this toolbox is that it uses system manifestation features (SMFs) for transdisciplinary modeling of these systems. The main challenges of implementation of the toolbox are functional design- and language-independent computational realization of the warehouses, and systematic development and management of the various evolving implements of SMFs (genotypes, phenotypes, and instances). Therefore, an information schema construct (ISC) based approach is proposed to create the schemata of the associated warehouse databases and the above-mentioned SMF implements. ISCs logically arrange the data contents of SMFs in a set of relational tables of varying semantics. In this article we present the ISCs necessary for creation of genotypes and phenotypes. They increase the efficiency of the database development process and make the data relationships transparent. Our follow-up research focuses on the elaboration of the SMF instances based system modeling methodology.

  15. FEATURE FUSION TECHNIQUE FOR COLOUR TEXTURE CLASSIFICATION SYSTEM BASED ON GRAY LEVEL CO-OCCURRENCE MATRIX

    Directory of Open Access Journals (Sweden)

    K. L. Shunmuganathan

    2012-01-01

    Full Text Available In this study, an efficient feature fusion based technique for the classification of colour texture images in VisTex album is presented. Gray Level Co-occurrence Matrix (GLCM and its associated texture features contrast, correlation, energy and homogeneity are used in the proposed approach. The proposed GLCM texture features are obtained from the original colour texture as well as the first non singleton dimension of the same image. These features are fused at feature level to classify the colour texture image using nearest neighbor classifier. The results demonstrate that the proposed fusion of difference image GLCM features is much more efficient than the original GLCM features.

  16. Mood Extraction Using Facial Features to Improve Learning Curves of Students in E-Learning Systems

    Directory of Open Access Journals (Sweden)

    Abdulkareem Al-Alwani

    2016-11-01

    Full Text Available Students’ interest and involvement during class lectures is imperative for grasping concepts and significantly improves academic performance of the students. Direct supervision of lectures by instructors is the main reason behind student attentiveness in class. Still, there is sufficient percentage of students who even under direct supervision tend to lose concentration. Considering the e-learning environment, this problem is aggravated due to absence of any human supervision. This calls for an approach to assess and identify lapses of attention by a student in an e-learning session. This study is carried out to improve student’s involvement in e-learning platforms by using their facial feature to extract mood patterns. Analyzing themoods based on emotional states of a student during an online lecture can provide interesting results which can be readily used to improvethe efficacy of content delivery in an e-learning platform. A survey is carried out among instructors involved in e-learning to identify most probable facial features that represent the facial expressions or mood patterns of a student. A neural network approach is used to train the system using facial feature sets to predict specific facial expressions. Moreover, a data association based algorithm specifically for extracting information on emotional states by correlating multiple sets of facial features is also proposed. This framework showed promising results in inciting student’s interest by varying the content being delivered.Different combinations of inter-related facial expressions for specific time frames were used to estimate mood patterns and subsequently level of involvement of a student in an e-learning environment.The results achieved during the course of research showed that mood patterns of a student provide a good correlation with his interest or involvement during online lectures and can be used to vary the content to improve students’ involvement in the e

  17. FEATURE FUSION TECHNIQUE FOR COLOUR TEXTURE CLASSIFICATION SYSTEM BASED ON GRAY LEVEL CO-OCCURRENCE MATRIX

    OpenAIRE

    Shunmuganathan, K. L.; A. Suresh

    2012-01-01

    In this study, an efficient feature fusion based technique for the classification of colour texture images in VisTex album is presented. Gray Level Co-occurrence Matrix (GLCM) and its associated texture features contrast, correlation, energy and homogeneity are used in the proposed approach. The proposed GLCM texture features are obtained from the original colour texture as well as the first non singleton dimension of the same image. These features are fused at feature level to classify the c...

  18. Suitability review of FMEA and reliability analysis for digital plant protection system and digital engineered safety features actuation system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, I. S.; Kim, T. K.; Kim, M. C.; Kim, B. S.; Hwang, S. W.; Ryu, K. C. [Hanyang Univ., Seoul (Korea, Republic of)

    2000-11-15

    Of the many items that should be checked out during a review stage of the licensing application for the I and C system of Ulchin 5 and 6 units, this report relates to a suitability review of the reliability analysis of Digital Plant Protection System (DPPS) and Digital Engineered Safety Features Actuation System (DESFAS). In the reliability analysis performed by the system designer, ABB-CE, fault tree analysis was used as the main methods along with Failure Modes and Effect Analysis (FMEA). However, the present regulatory technique dose not allow the system reliability analysis and its results to be appropriately evaluated. Hence, this study was carried out focusing on the following four items ; development of general review items by which to check the validity of a reliability analysis, and the subsequent review of suitability of the reliability analysis for Ulchin 5 and 6 DPPS and DESFAS L development of detailed review items by which to check the validity of an FMEA, and the subsequent review of suitability of the FMEA for Ulchin 5 and 6 DPPS and DESFAS ; development of detailed review items by which to check the validity of a fault tree analysis, and the subsequent review of suitability of the fault tree for Ulchin 5 and 6 DPPS and DESFAS ; an integrated review of the safety and reliability of the Ulchin 5 and 6 DPPS and DESFAS based on the results of the various reviews above and also of a reliability comparison between the digital systems and the comparable analog systems, i.e., and analog Plant Protection System (PPS) and and analog Engineered Safety Features Actuation System (ESFAS). According to the review mentioned above, the reliability analysis of Ulchin 5 and 6 DPPS and DESFAS generally satisfies the review requirements. However, some shortcomings of the analysis were identified in our review such that the assumed test periods for several equipment were not properly incorporated in the analysis, and failures of some equipment were not included in the

  19. Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.

    Directory of Open Access Journals (Sweden)

    Yagna P R Jarajapu

    Full Text Available Previously, we showed that insulin growth factor (IGF-1 binding protein-3 (IGFBP-3, independent of IGF-1, reduces pathological angiogenesis in a mouse model of the oxygen-induced retinopathy (OIR. The current study evaluates novel endothelium-dependent functions of IGFBP-3 including blood retinal barrier (BRB integrity and vasorelaxation. To evaluate vascular barrier function, either plasmid expressing IGFBP-3 under the regulation of an endothelial-specific promoter or a control plasmid was injected into the vitreous humor of mouse pups (P1 and compared to the non-injected eyes of the same pups undergoing standard OIR protocol. Prior to sacrifice, the mice were given an injection of horseradish peroxidase (HRP. IGFBP-3 plasmid-injected eyes displayed near-normal vessel morphology and enhanced vascular barrier function. Further, in vitro IGFBP-3 protects retinal endothelial cells from VEGF-induced loss of junctional integrity by antagonizing the dissociation of the junctional complexes. To assess the vasodilatory effects of IGFBP-3, rat posterior cerebral arteries were examined in vitro. Intraluminal IGFBP-3 decreased both pressure- and serotonin-induced constrictions by stimulating nitric oxide (NO release that were blocked by L-NAME or scavenger receptor-B1 neutralizing antibody (SRB1-Ab. Both wild-type and IGF-1-nonbinding mutant IGFBP-3 (IGFBP-3NB stimulated eNOS activity/NO release to a similar extent in human microvascular endothelial cells (HMVECs. NO release was neither associated with an increase in intracellular calcium nor decreased by Ca(2+/calmodulin-dependent protein kinase II (CamKII blockade; however, dephosphorylation of eNOS-Thr(495 was observed. Phosphatidylinositol 3-kinase (PI3K activity and Akt-Ser(473 phosphorylation were both increased by IGFBP-3 and selectively blocked by the SRB1-Ab or PI3K blocker LY294002. In conclusion, IGFBP-3 mediates protective effects on BRB integrity and mediates robust NO release to stimulate

  20. Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success

    Science.gov (United States)

    Kawamoto, Kensaku; Houlihan, Caitlin A; Balas, E Andrew; Lobach, David F

    2005-01-01

    Objective To identify features of clinical decision support systems critical for improving clinical practice. Design Systematic review of randomised controlled trials. Data sources Literature searches via Medline, CINAHL, and the Cochrane Controlled Trials Register up to 2003; and searches of reference lists of included studies and relevant reviews. Study selection Studies had to evaluate the ability of decision support systems to improve clinical practice. Data extraction Studies were assessed for statistically and clinically significant improvement in clinical practice and for the presence of 15 decision support system features whose importance had been repeatedly suggested in the literature. Results Seventy studies were included. Decision support systems significantly improved clinical practice in 68% of trials. Univariate analyses revealed that, for five of the system features, interventions possessing the feature were significantly more likely to improve clinical practice than interventions lacking the feature. Multiple logistic regression analysis identified four features as independent predictors of improved clinical practice: automatic provision of decision support as part of clinician workflow (P < 0.00001), provision of recommendations rather than just assessments (P = 0.0187), provision of decision support at the time and location of decision making (P = 0.0263), and computer based decision support (P = 0.0294). Of 32 systems possessing all four features, 30 (94%) significantly improved clinical practice. Furthermore, direct experimental justification was found for providing periodic performance feedback, sharing recommendations with patients, and requesting documentation of reasons for not following recommendations. Conclusions Several features were closely correlated with decision support systems' ability to improve patient care significantly. Clinicians and other stakeholders should implement clinical decision support systems that incorporate these

  1. Improving Bee Algorithm Based Feature Selection in Intrusion Detection System Using Membrane Computing

    Directory of Open Access Journals (Sweden)

    Kazeem I. Rufai

    2014-03-01

    Full Text Available Despite the great benefits accruable from the debut of computer and the internet, efforts are constantly being put up by fraudulent and mischievous individuals to compromise the integrity, confidentiality or availability of electronic information systems. In Cyber-security parlance, this is termed ‘intrusion’. Hence, this has necessitated the introduction of Intrusion Detection Systems (IDS to help detect and curb different types of attack. However, based on the high volume of data traffic involved in a network system, effects of redundant and irrelevant data should be minimized if a qualitative intrusion detection mechanism is genuinely desirous. Several attempts, especially feature subset selection approach using Bee Algorithm (BA, Linear Genetic Programming (LGP, Support Vector Decision Function Ranking (SVDF, Rough, Rough-DPSO, and Mutivariate Regression Splines (MARS have been advanced in the past to measure the dependability and quality of a typical IDS. The observed problem among these approaches has to do with their general performance. This has therefore motivated this research work. We hereby propose a new but robust algorithm called membrane algorithm to improve the Bee Algorithm based feature subset selection technique. This Membrane computing paradigm is a class of parallel computing devices. Data used were taken from KDD-Cup 99 Dataset which is the acceptable standard benchmark for intrusion detection. When the final results were compared to those of the existing approaches, using the three standard IDS measurements-Attack Detection, False Alarm and Classification Accuracy Rates, it was discovered that Bee Algorithm-Membrane Computing (BA-MC approach is a better technique. This is because our approach produced very high attack detection rate of 89.11%, classification accuracy of 95.60% and also generated a reasonable decrease in false alarm rate of 0.004. Receiver Operating Characteristic (ROC curve was used for results

  2. Characterizing the effects of feature salience and top-down attention in the early visual system.

    Science.gov (United States)

    Poltoratski, Sonia; Ling, Sam; McCormack, Devin; Tong, Frank

    2017-04-05

    The visual system employs a sophisticated balance of attentional mechanisms: salient stimuli are prioritized for visual processing, yet observers can also ignore such stimuli when their goals require directing attention elsewhere. A powerful determinant of visual salience is local feature contrast: if a local region differs from its immediate surround along one or more feature dimensions, it will appear more salient. Here, we used high-resolution fMRI at 7T to characterize the modulatory effects of bottom-up salience and top-down voluntary attention within multiple sites along the early visual pathway, including visual areas V1-V4 and the lateral geniculate nucleus (LGN). Observers viewed arrays of spatially distributed gratings, where one of the gratings immediately to the left or right of fixation differed from all other items in orientation or motion direction, making it salient. To investigate the effects of directed attention, observers were cued to attend to the grating to the left or right of fixation, which was either salient or non-salient. Results revealed reliable additive effects of top-down attention and stimulus-driven salience throughout visual areas V1-hV4. In comparison, the LGN exhibited significant attentional enhancement but was not reliably modulated by orientation- or motion-defined salience. Our findings indicate that top-down effects of spatial attention can influence visual processing at the earliest possible site along the visual pathway, including the LGN, while the processing of orientation- and motion-driven salience primarily involves feature-selective interactions that take place in early cortical visual areas.

  3. Patient- and system-related barriers for the earlier diagnosis of colorectal cancer

    OpenAIRE

    2009-01-01

    Abstract Background A cohort of colorectal cancer (CRC) patients represents an opportunity to study missed opportunities for earlier diagnosis. Primary objective: To study the epidemiology of diagnostic delays and failures to offer/complete CRC screening. Secondary objective: To identify system- and patient-related factors that may contribute to diagnostic delays or failures to offer/complete CRC screening. Methods Setting: Rural Veterans Administration (VA) Healthcare system. Participants: C...

  4. PLANET FORMATION IN STELLAR BINARIES. II. OVERCOMING THE FRAGMENTATION BARRIER IN α CENTAURI AND γ CEPHEI-LIKE SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Rafikov, Roman R.; Silsbee, Kedron, E-mail: rrr@astro.princeton.edu [Department of Astrophysical Sciences, Princeton University, Ivy Lane, Princeton, NJ 08540 (United States)

    2015-01-10

    Planet formation in small-separation (∼20 AU) eccentric binaries such as γ Cephei or α Centauri is believed to be adversely affected by the presence of the stellar companion. Strong dynamical excitation of planetesimals by the eccentric companion can result in collisional destruction (rather than growth) of 1-100 km objects, giving rise to the ''fragmentation barrier'' for planet formation. We revise this issue using a novel description of secular dynamics of planetesimals in binaries, which accounts for the gravity of the eccentric, coplanar protoplanetary disk, as well as gas drag. By studying planetesimal collision outcomes, we show, in contrast to many previous studies, that planetesimal growth and subsequent formation of planets (including gas giants) in AU-scale orbits within ∼20 AU separation binaries may be possible, provided that the protoplanetary disks are massive (≳ 10{sup –2} M {sub ☉}) and only weakly eccentric (disk eccentricity ≲ 0.01). These requirements are compatible with both the existence of massive (several M{sub J} ) planets in γ Cep-like systems and the results of recent simulations of gaseous disks in eccentric binaries. Terrestrial and Neptune-like planets can also form in lower-mass disks at small (sub-AU) radii. We find that the fragmentation barrier is less of a problem in eccentric disks that are apsidally aligned with the binary orbit. Alignment gives rise to special locations, where (1) relative planetesimal velocities are low and (2) the timescale of their drag-induced radial drift is long. This causes planetesimal pileup at such locations in the disk and promotes their growth locally, helping to alleviate the timescale problem for core formation.

  5. Multiple Adaptive Neuro-Fuzzy Inference System with Automatic Features Extraction Algorithm for Cervical Cancer Recognition

    Directory of Open Access Journals (Sweden)

    Mohammad Subhi Al-batah

    2014-01-01

    Full Text Available To date, cancer of uterine cervix is still a leading cause of cancer-related deaths in women worldwide. The current methods (i.e., Pap smear and liquid-based cytology (LBC to screen for cervical cancer are time-consuming and dependent on the skill of the cytopathologist and thus are rather subjective. Therefore, this paper presents an intelligent computer vision system to assist pathologists in overcoming these problems and, consequently, produce more accurate results. The developed system consists of two stages. In the first stage, the automatic features extraction (AFE algorithm is performed. In the second stage, a neuro-fuzzy model called multiple adaptive neuro-fuzzy inference system (MANFIS is proposed for recognition process. The MANFIS contains a set of ANFIS models which are arranged in parallel combination to produce a model with multi-input-multioutput structure. The system is capable of classifying cervical cell image into three groups, namely, normal, low-grade squamous intraepithelial lesion (LSIL and high-grade squamous intraepithelial lesion (HSIL. The experimental results prove the capability of the AFE algorithm to be as effective as the manual extraction by human experts, while the proposed MANFIS produces a good classification performance with 94.2% accuracy.

  6. A soft computing based approach using modified selection strategy for feature reduction of medical systems.

    Science.gov (United States)

    Zuhtuogullari, Kursat; Allahverdi, Novruz; Arikan, Nihat

    2013-01-01

    The systems consisting high input spaces require high processing times and memory usage. Most of the attribute selection algorithms have the problems of input dimensions limits and information storage problems. These problems are eliminated by means of developed feature reduction software using new modified selection mechanism with middle region solution candidates adding. The hybrid system software is constructed for reducing the input attributes of the systems with large number of input variables. The designed software also supports the roulette wheel selection mechanism. Linear order crossover is used as the recombination operator. In the genetic algorithm based soft computing methods, locking to the local solutions is also a problem which is eliminated by using developed software. Faster and effective results are obtained in the test procedures. Twelve input variables of the urological system have been reduced to the reducts (reduced input attributes) with seven, six, and five elements. It can be seen from the obtained results that the developed software with modified selection has the advantages in the fields of memory allocation, execution time, classification accuracy, sensitivity, and specificity values when compared with the other reduction algorithms by using the urological test data.

  7. Automatic Meal Inspection System Using LBP-HF Feature for Central Kitchen

    Directory of Open Access Journals (Sweden)

    Yue-Min Jiang

    2015-02-01

    Full Text Available This paper proposes an intelligent and automatic meal inspection system which can be applied to the meal inspection for the application of central kitchen automation. The diet specifically designed for the patients are required with providing personalized diet such as low sodium intake or some necessary food. Hence, the proposed system can benefit the inspection process that is often performed manually. In the proposed system, firstly, the meal box can be detected and located automatically with the vision-based method and then all the food ingredients can be identified by using the color and LBP-HF texture features. Secondly, the quantity for each of food ingredient is estimated by using the image depth information. The experimental results show that the meal inspection accuracy can approach 80%, meal inspection efficiency can reach1200ms, and the food quantity accuracy is about 90%. The proposed system is expected to increase the capacity of meal supply over 50% and be helpful to the dietician in the hospital for saving the time in the diet inspection process.

  8. EEG-Based BCI System Using Adaptive Features Extraction and Classification Procedures

    Science.gov (United States)

    Mangia, Anna Lisa; Cappello, Angelo

    2016-01-01

    Motor imagery is a common control strategy in EEG-based brain-computer interfaces (BCIs). However, voluntary control of sensorimotor (SMR) rhythms by imagining a movement can be skilful and unintuitive and usually requires a varying amount of user training. To boost the training process, a whole class of BCI systems have been proposed, providing feedback as early as possible while continuously adapting the underlying classifier model. The present work describes a cue-paced, EEG-based BCI system using motor imagery that falls within the category of the previously mentioned ones. Specifically, our adaptive strategy includes a simple scheme based on a common spatial pattern (CSP) method and support vector machine (SVM) classification. The system's efficacy was proved by online testing on 10 healthy participants. In addition, we suggest some features we implemented to improve a system's “flexibility” and “customizability,” namely, (i) a flexible training session, (ii) an unbalancing in the training conditions, and (iii) the use of adaptive thresholds when giving feedback. PMID:27635129

  9. The Atmospheric Imaging Array Feature and Event System (AFES) for SDO

    Science.gov (United States)

    Hurlburt, N.; Freeland, S.; Cheung, M.; Schrijver, C.

    2008-05-01

    The great data volumes involved in Solar Dynamics Observatory impose the need to have efficient means to access, process and transport data products that goes beyond basic data discovery. In order to reduce system requirements and to improve scientific productivity, we pre-package Ðinterestingî datasets and direct scientists to them through an event-based querying system. This will enable caching of commonly accessed datasets within the Joint Science Operations Center (JSOC) and reduces the (human) time spent searching for and downloading relevant data. This system leverages the infrastructure developed for the Hinode Observation System (http://sot.lmsal.com/sot-data) and incorporates elements of the evolving heliophysics knowledgebase (http://www.lmsal.com/helio-informatics/hpkb). We present the details of the AFES including the ingestion of images, automated and manual tools for identifying and annotation features within the images, and interfaces and webtools for querying and accessing events and their associated data. This work has been supported by NASA through contract NNG04AE00C and Lockheed Martin Research Funds.

  10. A Soft Computing Based Approach Using Modified Selection Strategy for Feature Reduction of Medical Systems

    Directory of Open Access Journals (Sweden)

    Kursat Zuhtuogullari

    2013-01-01

    Full Text Available The systems consisting high input spaces require high processing times and memory usage. Most of the attribute selection algorithms have the problems of input dimensions limits and information storage problems. These problems are eliminated by means of developed feature reduction software using new modified selection mechanism with middle region solution candidates adding. The hybrid system software is constructed for reducing the input attributes of the systems with large number of input variables. The designed software also supports the roulette wheel selection mechanism. Linear order crossover is used as the recombination operator. In the genetic algorithm based soft computing methods, locking to the local solutions is also a problem which is eliminated by using developed software. Faster and effective results are obtained in the test procedures. Twelve input variables of the urological system have been reduced to the reducts (reduced input attributes with seven, six, and five elements. It can be seen from the obtained results that the developed software with modified selection has the advantages in the fields of memory allocation, execution time, classification accuracy, sensitivity, and specificity values when compared with the other reduction algorithms by using the urological test data.

  11. Electro-Catalysis System for Biodiesel Synthesis from Palm Oil over Dielectric-Barrier Discharge Plasma Reactor

    Directory of Open Access Journals (Sweden)

    Istadi Istadi

    2014-07-01

    Full Text Available Biodiesel synthesis reaction routes from palm oil using plasma electro-catalysis process over Dielectric-Barrier Discharge (DBD plasma reactor were studied. The study was focused on finding possible reaction mechanism route during plasma electro-catalysis process. The prediction was performed based on the changes of Gas Chromatography Mass Spectrometer (GC-MS and Fourier Transform Infra Red (FT-IR analyses to the biodiesel products with respect to time length of plasma treatment. It was found that main reaction mechanism occurred in the plasma electro-catalysis system was non-thermal pyrolysis rather than transesterification. The main reactions within the plasma treatment were due to collision between high energetic electrons (supplied from high voltage power supply through high voltage electrode and the reaction mixtures. The high energetic electrons affected the electrons pair of covalent bonding to be excited or dissociated even ionized at higher energy. Therefore, this plasma electro-catalysis system was promising for biodiesel synthesis from vegetable oils due to only very short time reaction was needed, even no need a catalyst, no soap formation, and no glycerol by-product. This system could produce fatty acid methyl ester yield of 75.65% at 120 seconds and other possible chemicals, such as alkynes, alkanes, esters, carboxylic acid, and aldehydes. However, during the plasma process, the reaction mechanisms were still difficult to be controlled due the action of available high energetic electrons. The advanced studies on how to control the reaction mechanism selectively in the plasma electro-catalysis will be published elsewhere. © 2014 BCREC UNDIP. All rights reservedReceived: 23rd January 2014; Revised: 20th March 2014; Accepted: 23rd March 2014[How to Cite: Istadi, I., Yudhistira, A.D., Anggoro, D.D., Buchori, L. (2014. Electro-Catalysis System for Biodiesel Synthesis from Palm Oil over Dielectric-Barrier Discharge Plasma Reactor

  12. Distinctive features of NREM parasomnia behaviors in parkinson's disease and multiple system atrophy.

    Directory of Open Access Journals (Sweden)

    Pietro-Luca Ratti

    Full Text Available To characterize parasomnia behaviors on arousal from NREM sleep in Parkinson's Disease (PD and Multiple System Atrophy (MSA.From 30 patients with PD, Dementia with Lewy Bodies/Dementia associated with PD, or MSA undergoing nocturnal video-polysomnography for presumed dream enactment behavior, we were able to select 2 PD and 2 MSA patients featuring NREM Parasomnia Behviors (NPBs. We identified episodes during which the subjects seemed to enact dreams or presumed dream-like mentation (NPB arousals versus episodes with physiological movements (no-NPB arousals. A time-frequency analysis (Morlet Wavelet Transform of the scalp EEG signals around each NPB and no- NPB arousal onset was performed, and the amplitudes of the spectral frequencies were compared between NPB and no-NPB arousals.19 NPBs were identified, 12 of which consisting of 'elementary' NPBs while 7 resembling confusional arousals. With quantitative EEG analysis, we found an amplitude reduction in the 5-6 Hz band 40 seconds before NPBs arousal as compared to no-NPB arousals at F4 and C4 derivations (p<0.01.Many PD and MSA patients feature various NREM sleep-related behaviors, with clinical and electrophysiological differences and similarities with arousal parasomnias in the general population.This study help bring to attention an overlooked phenomenon in neurodegenerative diseases.

  13. Work improvement and occupational safety and health management systems: common features and research needs.

    Science.gov (United States)

    Kogi, Kazutaka

    2002-04-01

    There is a growing trend in re-orientating occupational health research towards risk management. Such a trend is accelerated by the increasing attention to occupational safety and health management systems. The trend, also seen in many Asian countries, is offering new opportunities for strengthening primary prevention. Useful examples are provided from recent work improvement projects dealing with technology transfer, small workplaces and rural areas. Common features of both these work improvement projects and accepted occupational risk management principles are reviewed based on recent experiences in Asian countries. Such features seem highly relevant in examining the occupational health research strategies. These experiences clearly show that locally adjusted procedures for risk assessment and control must be developed. There are new research needs concerning (a) the effective ways to encourage voluntary control at the workplace; (b) practical methods for local risk assessment; and (c) the types of participatory steps leading to continual improvements in the varying local context. Criteria of action-oriented research that can contribute to more effective risk control in different settings are discussed. Six relevant criteria may be mentioned: (a) adaptive risk management; (b) work/risk relationships; (c) action-oriented risk assessment; (d) use of collective expertise; (e) participation of local people; and (f) mutual learning. It appears crucial to stimulate research into the practical risk control procedures adjusted to the local situation.

  14. FEATURE DIMENSION REDUCTION FOR EFFICIENT MEDICAL IMAGE RETRIEVAL SYSTEM USING UNIFIED FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Yogapriya Jaganathan

    2013-01-01

    Full Text Available Feature dimensionality reduction problem is a major issue in Content Based Medical Image Retrieval (CBMIR for the effective management of medical images with the support of visual features for the purpose of diagnosis and educational research field. However, high dimensional features would be an origin for substantial challenges in retrieval. The proposed CBMIR is used a unified approach based on extraction of visual features, optimized feature selection, classification of optimized features and similarity measurements. However, high dimensional features would be an origin for substantial challenges in retrieval. The Texture features are selected using Gray Level Co-occurrence Matrix (GLCM, Tamura Features (TF and Gabor Filter (GF in which pull out of features are formed a feature vector database. Fuzzy based PSO (FPSO is applied for Feature selection to overcome the difficulty of feature vectors being surrounded in local optima of original PSO. This procedure also integrates a smart policymaking structure of ACO procedure into the novel FPSO where the global optimum position to be exclusive for every feature particle. The Fuzzy based Particle Swarm Optimization and Ant Colony Optimization (FPSO-ACO technique is used to trim down the feature vector dimensionality and classification is accomplished using an extensive Fuzzy based Relevance Vector Machine (FRVM to form collections of relevant image features that would provide an accepted way to classify dimensionally concentrated feature vectors of images. The Euclidean Distance (ED is recognized as finest for similarity measurement between the medical query image and the medical image database. This proposed approach can acquire the query from the user and had retrieved the desired images from the database. The retrieval performance would be assessed based on precision and recall. This proposed CBMIR is used to provide comfort to the physician to obtain more assurance in their decisions for

  15. Sclerosing cholangitis: Clinicopathologic features, imaging spectrum, and systemic approach to differential diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Ni Eun [Dept. of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of); Kim, So Yeon; Lee, Seung Soo; Byun, Jae Ho; Kim, Hyoung Jung; Kim, Jin Hee; Lee, Moon Gyu [Dept. of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2016-02-15

    Sclerosing cholangitis is a spectrum of chronic progressive cholestatic liver disease characterized by inflammation, fibrosis, and stricture of the bile ducts, which can be classified as primary and secondary sclerosing cholangitis. Primary sclerosing cholangitis is a chronic progressive liver disease of unknown cause. On the other hand, secondary sclerosing cholangitis has identifiable causes that include immunoglobulin G4-related sclerosing disease, recurrent pyogenic cholangitis, ischemic cholangitis, acquired immunodeficiency syndrome-related cholangitis, and eosinophilic cholangitis. In this review, we suggest a systemic approach to the differential diagnosis of sclerosing cholangitis based on the clinical and laboratory findings, as well as the typical imaging features on computed tomography and magnetic resonance (MR) imaging with MR cholangiography. Familiarity with various etiologies of sclerosing cholangitis and awareness of their typical clinical and imaging findings are essential for an accurate diagnosis and appropriate management.

  16. Generalized Lymphadenopathy as Presenting Feature of Systemic Lupus Erythematosus: Case Report and Review of the Literature

    Science.gov (United States)

    Afzal, Wais; Arab, Talal; Ullah, Tofura; Teller, Katerina; Doshi, Kaushik J.

    2016-01-01

    Lymphadenopathy could represent a vast spectrum of etiologies including infectious and non-infectious diseases. Besides proper history taking, physical examination, and laboratory investigations, a tissue diagnosis is often necessary to unmask the cause of generalized lymphadenopathy. Here we present a 23-year-old woman who was admitted for diffuse generalized lymphadenopathy, fatigue, malaise, weight loss, nausea, and bilateral lower extremity edema. She reported a history of seizures as well as stroke 2 years prior with no other medical conditions present. Although malignant and infectious etiologies were initially the primary targets for workup, her history of seizures and stroke remained a dilemma. Extensive workup for malignant and infectious diseases was unrevealing; however, rheumatologic workup was eventually positive for systemic lupus erythematosus (SLE). This case illustrates that extensive generalized diffuse lymphadenopathy may be a presenting feature of SLE and should be considered in the differential diagnosis of patients presenting with diffuse lymphadenopathy and constitutional symptoms. PMID:27738484

  17. LQR Feedback Control Development for Wind Turbines Featuring a Digital Fluid Power Transmission System

    DEFF Research Database (Denmark)

    Pedersen, Niels Henrik; Johansen, Per; Andersen, Torben O.

    2016-01-01

    Research within digital fluid power (DFP) transmissions is receiving an increased attention as an alternative to conventional transmission technologies. The use of DFP displacement machines entail a need for applicable control algorithms. However, the design and analysis of controllers...... for such digital systems are complicated by its non-smooth behavior. In this paper a control design approach for a digital displacement machine® is proposed and a performance analysis of a wind turbine using a DFP transmission is presented. The performance evaluation is based on a dynamic model of the transmission...... invariant model. Using full-field flow wind profiles as input, the design approach and control performance is verified by simulation in the dynamic model of the wind turbine featuring the DFP transmission. Additionally, the performance is compared to that of the conventional NREL reference turbine...

  18. Institutional and structural barriers for implementing on-farm water saving irrigation systems

    DEFF Research Database (Denmark)

    Pedersen, Søren Marcus; Boesen, Mads Vejlby; Ørum, Jens Erik

    2013-01-01

    Population growth and increased global water demand has intensified the need to apply water more efficiently. As the main global water user the agricultural sector needs special attention. In this study, the water saving potential of new drip irrigation systems has been investigated in five diffe...

  19. 78 FR 53467 - John H. Chafee Coastal Barrier Resources System; Delaware, North Carolina, South Carolina...

    Science.gov (United States)

    2013-08-29

    ..., as well as areas along the coasts of the Great Lakes, the U.S. Virgin Islands, and Puerto Rico. The... reclassified from T08P (an otherwise protected area) to T08 (a System unit). T11, T11P: SOUTH PADRE ISLAND UNIT... break between the Laguna Madre and South Padre Island that is visible on the base imagery. T12:...

  20. Chronic arthritis in systemic lupus erythematosus: distinct features in 336 paediatric and 1830 adult patients.

    Science.gov (United States)

    Gormezano, Natali W S; Silva, Clovis A; Aikawa, Nadia E; Barros, Diego L; da Silva, Mariana A; Otsuzi, Carini I; Kozu, Katia; Seguro, Luciana Parente; Pereira, Rosa M R; Bonfá, Eloisa

    2016-01-01

    The objectives of this study are to assess the frequency of chronic arthritis and compare the clinical and laboratory features in a large population of childhood-onset systemic lupus erythematosus (cSLE) and adult-onset (aSLE) patients. This historical study evaluated 336 cSLE and 1830 aSLE patients. Chronic arthritis was defined as synovitis of at least 6 weeks of duration. Rhupus was characterised as the association of SLE and chronic inflammatory arthritis with erosion and positive rheumatoid factor. Jaccoud's arthropathy is a non-erosive subluxation leading to severe deformity of the hands and feet. Data were compared using Student's t test or the Mann-Whitney test for continuous variables. For categorical variables, differences were assessed by Fisher's exact test and Pearson chi-square. Frequencies of chronic arthritis were similar in cSLE and aSLE (2.4 vs. 3.8%, p = 0.261). The median time from disease onset to appearance of chronic arthritis was shorter in cSLE (0 vs. 10 years, p lupus anticoagulant (40 vs. 1.6%, p = 0.012), anticardiolipin IgM (40 vs. 1.5%, p = 0.012) and median Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) [10.5(1-20) vs. 6(4-16), p = 0.029] were higher in cSLE. Frequency of rhupus, (12 vs. 17%, p = 1.0), Jaccoud's arthropathy (0 vs. 17%, p = 0.343) and treatments were similar in cSLE and aSLE. We determined that chronic arthritis in SLE has distinct features in children, with very early onset, polyarticular involvement and association with active disease. We further demonstrated in this series that a proportion of chronic arthritis involvement in SLE is manifested as rhupus and Jaccoud's arthropathy.

  1. Identification of features of electronic prescribing systems to support quality and safety in primary care using a modified Delphi process

    Directory of Open Access Journals (Sweden)

    O'Neill Jennifer A

    2010-04-01

    Full Text Available Abstract Background Electronic prescribing is increasingly being used in primary care and in hospitals. Studies on the effects of e-prescribing systems have found evidence for both benefit and harm. The aim of this study was to identify features of e-prescribing software systems that support patient safety and quality of care and that are useful to the clinician and the patient, with a focus on improving the quality use of medicines. Methods Software features were identified by a literature review, key informants and an expert group. A modified Delphi process was used with a 12-member multidisciplinary expert group to reach consensus on the expected impact of the features in four domains: patient safety, quality of care, usefulness to the clinician and usefulness to the patient. The setting was electronic prescribing in general practice in Australia. Results A list of 114 software features was developed. Most of the features relate to the recording and use of patient data, the medication selection process, prescribing decision support, monitoring drug therapy and clinical reports. The expert group rated 78 of the features (68% as likely to have a high positive impact in at least one domain, 36 features (32% as medium impact, and none as low or negative impact. Twenty seven features were rated as high positive impact across 3 or 4 domains including patient safety and quality of care. Ten features were considered "aspirational" because of a lack of agreed standards and/or suitable knowledge bases. Conclusions This study defines features of e-prescribing software systems that are expected to support safety and quality, especially in relation to prescribing and use of medicines in general practice. The features could be used to develop software standards, and could be adapted if necessary for use in other settings and countries.

  2. Laboratory column studies for evaluating a barrier system for providing oxygen and substrate for TCE biodegradation.

    Science.gov (United States)

    Kao, C M; Chen, S C; Su, M C

    2001-08-01

    The industrial solvent trichloroethylene (TCE) is among the most ubiquitous chlorinated compounds found in groundwater contamination. The objective of this study was to develop a biobarrier system containing oxygen-organic releasing material to enhance the aerobic cometabolism of TCE in situ. The oxygen-organic material, which contains calcium peroxide and peat, is able to release oxygen and primary substrates continuously upon contact with water. Batch experiments were conducted to design and identify the components of the oxygen-organic releasing material, and evaluate the oxygen and organic substrate (presented as COD equivalent) release from the designed oxygen-organic material. The observed oxygen and chemical oxygen demand (COD) release rates were approximately 0.0246 and 0.052 mg/d/g of material, respectively. A laboratory-scale column experiment was then conducted to evaluate the feasibility of this proposed system for the bioremediation of TCE-contaminated groundwater. This system was performed using a series of continuous-flow glass columns including a soil column, an oxygen-organic material column, followed by two consecutive soil columns. Aerobic acclimated sludges were inoculated in all three soil columns to provide microbial consortia for TCE biodegradation. Simulated TCE-contaminated groundwater with a flow rate of 0.25 l/day was pumped into this system. Effluent samples from each column were analyzed for TCE and other indicating parameters (e.g., pH, dissolved oxygen). Results show that the decreases in TCE concentrations were observed over a 4-month operating period. Up to 99% of TCE removal efficiency was obtained in this passive system. Results indicate that the continuously released oxygen and organic substrates from the oxygen-organic materials enhanced TCE biotransformation. Thus, the biobarrier treatment scheme has the potential to be developed into an environmentally and economically acceptable remediation technology.

  3. Barrier mechanisms in the Drosophila blood-brain barrier

    Directory of Open Access Journals (Sweden)

    Samantha Jane Hindle

    2014-12-01

    Full Text Available The invertebrate blood-brain barrier field is growing at a rapid pace and, in recent years, studies have shown a physiologic and molecular complexity that has begun to rival its vertebrate counterpart. Novel mechanisms of paracellular barrier maintenance through GPCR signaling were the first demonstrations of the complex adaptive mechanisms of barrier physiology. Building upon this work, the integrity of the invertebrate blood-brain barrier has recently been shown to require coordinated function of all layers of the compound barrier structure, analogous to signaling between the layers of the vertebrate neurovascular unit. These findings strengthen the notion that many blood-brain barrier mechanisms are conserved between vertebrates and invertebrates, and suggest that novel findings in invertebrate model organisms will have a significant impact on the understanding of vertebrate BBB functions. In this vein, important roles in coordinating localized and systemic signaling to dictate organism development and growth are beginning to show how the blood-brain barrier can govern whole animal physiologies. This includes novel functions of blood-brain barrier gap junctions in orchestrating synchronized neuroblast proliferation, and of blood-brain barrier secreted antagonists of insulin receptor signaling. These advancements and others are pushing the field forward in exciting new directions. In this review, we provide a synopsis of invertebrate blood-brain barrier anatomy and physiology, with a focus on insights from the past 5 years, and highlight important areas for future study.

  4. Functionality of system components: Conservation of protein function in protein feature space

    DEFF Research Database (Denmark)

    Jensen, Lars Juhl; Ussery, David; Brunak, Søren

    2003-01-01

    Many protein features useful for prediction of protein function can be predicted from sequence, including posttranslational modifications, subcellular localization, and physical/chemical properties. We show here that such protein features are more conserved among orthologs than paralogs, indicati...

  5. Random Forest Based Coarse Locating and KPCA Feature Extraction for Indoor Positioning System

    Directory of Open Access Journals (Sweden)

    Yun Mo

    2014-01-01

    Full Text Available With the fast developing of mobile terminals, positioning techniques based on fingerprinting method draw attention from many researchers even world famous companies. To conquer some shortcomings of the existing fingerprinting systems and further improve the system performance, on the one hand, in the paper, we propose a coarse positioning method based on random forest, which is able to customize several subregions, and classify test point to the region with an outstanding accuracy compared with some typical clustering algorithms. On the other hand, through the mathematical analysis in engineering, the proposed kernel principal component analysis algorithm is applied for radio map processing, which may provide better robustness and adaptability compared with linear feature extraction methods and manifold learning technique. We build both theoretical model and real environment for verifying the feasibility and reliability. The experimental results show that the proposed indoor positioning system could achieve 99% coarse locating accuracy and enhance 15% fine positioning accuracy on average in a strong noisy environment compared with some typical fingerprinting based methods.

  6. Emergent auditory feature tuning in a real-time neuromorphic VLSI system

    Directory of Open Access Journals (Sweden)

    Sadique eSheik

    2012-02-01

    Full Text Available Many sounds of ecological importance, such as communication calls, are characterised by time-varying spectra. However, most neuromorphic auditory models to date have focused on distinguishing mainly static patterns, under the assumption that dynamic patterns can be learned as sequences of static ones. In contrast, the emergence of dynamic feature sensitivity through exposure to formative stimuli has been recently modeled in a network of spiking neurons based on the thalamocortical architecture. The proposed network models the effect of lateral and recurrent connections between cortical layers, distance-dependent axonal transmission delays, and learning in the form of Spike Timing Dependent Plasticity (STDP, which effects stimulus-driven changes in the pattern of network connectivity. In this paper we demonstrate how these principles can be efficiently implemented in neuromorphic hardware. In doing so we address two principle problems in the design of neuromorphic systems: real-time event-based asynchronous communication in multi-chip systems, and the realization in hybrid analog/digital VLSI technology of neural computational principles that we propose underlie plasticity in neural processing of dynamic stimuli. The result is a hardware neural network that learns in real-time and shows preferential responses, after exposure, to stimuli exhibiting particular spectrotemporal patterns. The availability of hardware on which the model can be implemented, makes this a significant step towards the development of adaptive, neurobiologically plausible, spike-based, artificial sensory systems.

  7. Emergent Auditory Feature Tuning in a Real-Time Neuromorphic VLSI System.

    Science.gov (United States)

    Sheik, Sadique; Coath, Martin; Indiveri, Giacomo; Denham, Susan L; Wennekers, Thomas; Chicca, Elisabetta

    2012-01-01

    Many sounds of ecological importance, such as communication calls, are characterized by time-varying spectra. However, most neuromorphic auditory models to date have focused on distinguishing mainly static patterns, under the assumption that dynamic patterns can be learned as sequences of static ones. In contrast, the emergence of dynamic feature sensitivity through exposure to formative stimuli has been recently modeled in a network of spiking neurons based on the thalamo-cortical architecture. The proposed network models the effect of lateral and recurrent connections between cortical layers, distance-dependent axonal transmission delays, and learning in the form of Spike Timing Dependent Plasticity (STDP), which effects stimulus-driven changes in the pattern of network connectivity. In this paper we demonstrate how these principles can be efficiently implemented in neuromorphic hardware. In doing so we address two principle problems in the design of neuromorphic systems: real-time event-based asynchronous communication in multi-chip systems, and the realization in hybrid analog/digital VLSI technology of neural computational principles that we propose underlie plasticity in neural processing of dynamic stimuli. The result is a hardware neural network that learns in real-time and shows preferential responses, after exposure, to stimuli exhibiting particular spectro-temporal patterns. The availability of hardware on which the model can be implemented, makes this a significant step toward the development of adaptive, neurobiologically plausible, spike-based, artificial sensory systems.

  8. Gut barrier in health and disease: focus on childhood.

    Science.gov (United States)

    Viggiano, D; Ianiro, G; Vanella, G; Bibbò, S; Bruno, G; Simeone, G; Mele, G

    2015-01-01

    The gut barrier is a functional unit, organized as a multi-layer system, made up of two main components: a physical barrier surface, which prevents bacterial adhesion and regulates paracellular diffusion to the host tissues, and a deep functional barrier, that is able to discriminate between pathogens and commensal microorganisms, organizing the immune tolerance and the immune response to pathogens. Other mechanisms, such as gastric juice and pancreatic enzymes (which both have antibacterial properties) participate in the luminal integrity of the gut barrier. From the outer layer to the inner layer, the physical barrier is composed of gut microbiota (that competes with pathogens to gain space and energy resources, processes the molecules necessary to mucosal integrity and modulates the immunological activity of deep barrier), mucus (which separates the intraluminal content from more internal layers and contains antimicrobial products and secretory IgA), epithelial cells (which form a physical and immunological barrier) and the innate and adaptive immune cells forming the gut-associated lymphoid tissue (which is responsible for antigen sampling and immune responses). Disruption of the gut barrier has been associated with many gastrointestinal diseases, but also with extra-intestinal pathological condition, such as type 1 diabetes mellitus, allergic diseases or autism spectrum disorders. The maintenance of a healthy intestinal barrier is therefore of paramount importance in children, for both health and economic reasons. Many drugs or compounds used in the treatment of gastrointestinal disorders act through the restoration of a normal intestinal permeability. Several studies have highlighted the role of probiotics in the modulation and reduction of intestinal permeability, considering the strong influence of gut microbiota in the modulation of the function and structure of gut barrier, but also on the immune response of the host. To date, available weapons for the

  9. Barriers to the implementation of quality management system in media organizations in pakistan: an empirical study

    Directory of Open Access Journals (Sweden)

    Muhammad Naveed Anwar

    2012-12-01

    Full Text Available Quality management system has played pivotal role in establishing organizational functions and processes in the very right perspective of a very well knitted system of documentation, training and implementation. Media organizations are so close in their very existence and social structure and they are more than needed to stream line their processes as their impact on social life is significant and considerable. This study encompasses the top news channels in Pakistan and recorded the views of their top management with respect to their feelings pertaining to QMS. This study is very first one of its kinds in Pakistan and it is hoped that it may open more doors for future research avenues in this very area.

  10. REMOVAL OF ADDED NITRATE IN THE SINGLE, BINARY, AND TERNARY SYSTEMS OF COTTON BURR COMPOST, ZEROVALENT IRON, AND SEDIMENT: IMPLICATIONS FOR GROUNDWATER NITRATE REMEDIATION USING PERMEABLE REACTIVE BARRIERS

    Science.gov (United States)

    Recent research has shown that carbonaceous solid materials and zerovalent iron (Fe0) may potentially be used as media in permeable reactive barriers (PRBs) to degrade groundwater nitrate via heterotrophic denitrification in the solid carbon system, and via abiotic reduction and ...

  11. When health systems are barriers to health care: challenges faced by uninsured Mexican kidney patients.

    Directory of Open Access Journals (Sweden)

    Ciara Kierans

    Full Text Available BACKGROUND: Chronic Kidney Disease disproportionately affects the poor in Low and Middle Income Countries (LMICs. Mexico exemplifies the difficulties faced in supporting Renal Replacement Therapy (RRT and providing equitable patient care, despite recent attempts at health reform. The objective of this study is to document the challenges faced by uninsured, poor Mexican families when attempting to access RRT. METHODS: The article takes an ethnographic approach, using interviewing and observation to generate detailed accounts of the problems that accompany attempts to secure care. The study, based in the state of Jalisco, comprised interviews with patients, their caregivers, health and social care professionals, among others. Observations were carried out in both clinical and social settings. RESULTS: In the absence of organised health information and stable pathways to renal care, patients and their families work extraordinarily hard and at great expense to secure care in a mixed public-private healthcare system. As part of this work, they must navigate challenging health and social care environments, negotiate treatments and costs, resource and finance healthcare and manage a wide range of formal and informal health information. CONCLUSIONS: Examining commonalities across pathways to adequate healthcare reveals major failings in the Mexican system. These systemic problems serve to reproduce and deepen health inequalities. A system, in which the costs of renal care are disproportionately borne by those who can least afford them, faces major difficulties around the sustainability and resourcing of RRTs. Attempts to increase access to renal therapies, therefore, need to take into account the complex social and economic demands this places on those who need access most. This paper further shows that ethnographic studies of the concrete ways in which healthcare is accessed in practice provide important insights into the plight of CKD patients and so

  12. Conceptual Model for Radionuclide Release from the Engineered Barrier Systems (EBS) at Yucca Mountain

    Science.gov (United States)

    Hamdan, L. K.; Walton, J.; Woocay, A.

    2008-12-01

    Over time, nuclear waste packages at Yucca Mountain repository are likely to fail gradually or in stages, due to general or localized corrosion. Rock fall and other physical (or chemical) disturbances will lead to different general corrosion rates and different times of penetration. In the long run, the waste package is likely to evolve into a combination of failure locations mixed with relicts of intact Alloy-22 (or other waste package materials). Release of radionuclides (mostly by dissolution in water) from the waste packages is one of the most important factors determining the performance of the proposed Yucca Mountain repository. In this paper we develop a conceptual model of radionuclide release from the EBS. In this system, residual heat release in the waste, in conjunction with the capillary effect, is anticipated to set up flow systems in the relict protected areas, where liquid water flows into the protected area toward the warmest region, and vapor flows outward away from the warmest region - effectively preventing release and sometimes sequestering radionuclides in the relict sheltered areas (dead ends). We derive a dimensionless group that specifies the condition for the internal heat driven flow system, and estimates the minimum size of the covered areas required to sequester radionuclides and prevent release. Over time, the minimum area required for protection slowly increases while general corrosion decreases the average size of relict areas. Convolution of the two processes suggests that radionuclide release from the flow-through system of partially failed waste packages will be gradual and long delayed (100,000 - 1,000,000 years), even in the case of early penetration by localized corrosion.

  13. The EcoKI Type I Restriction-Modification System in Escherichia coli Affects but Is Not an Absolute Barrier for Conjugation

    DEFF Research Database (Denmark)

    Roer, Louise; Aarestrup, Frank Møller; Hasman, Henrik

    2015-01-01

    results about restriction-modification systems based on phenotypic studies have been presented as reasons for a barrier to conjugation with and other means of uptake of exogenous DNA. In this study, we show that inactivation of the R.EcoKI restriction enzyme in strain Escherichia coli K-12 strain MG1655...... of the mutant recipient with a disrupted hsdR gene. This leads to the conclusion that EcoKI restriction-modification affects the uptake of DNA by conjugation but is not a major barrier to plasmid transfer....

  14. Designing using manufacturing features

    Science.gov (United States)

    Szecsi, T.; Hoque, A. S. M.

    2012-04-01

    This paper presents a design system that enables the composition of a part using manufacturing features. Features are selected from feature libraries. Upon insertion, the system ensures that the feature does not contradict the design-for-manufacture rules. This helps eliminating costly manufacturing problems. The system is developed as an extension to a commercial CAD/CAM system Pro/Engineer.

  15. Patient- and system-related barriers for the earlier diagnosis of colorectal cancer

    Science.gov (United States)

    Wahls, Terry L; Peleg, Ika

    2009-01-01

    Background A cohort of colorectal cancer (CRC) patients represents an opportunity to study missed opportunities for earlier diagnosis. Primary objective: To study the epidemiology of diagnostic delays and failures to offer/complete CRC screening. Secondary objective: To identify system- and patient-related factors that may contribute to diagnostic delays or failures to offer/complete CRC screening. Methods Setting: Rural Veterans Administration (VA) Healthcare system. Participants: CRC cases diagnosed within the VA between 1/1/2000 and 3/1/2007. Data sources: progress notes, orders, and pathology, laboratory, and imaging results obtained between 1/1/1995 and 12/31/2007. Completed CRC screening was defined as a fecal occult blood test or flexible sigmoidoscopy (both within five years), or colonoscopy (within 10 years); delayed diagnosis was defined as a gap of more than six months between an abnormal test result and evidence of clinician response. A summary abstract of the antecedent clinical care for each patient was created by a certified gastroenterologist (GI), who jointly reviewed and coded the abstracts with a general internist (TW). Results The study population consisted of 150 CRC cases that met the inclusion criteria. The mean age was 69.04 (range 35-91); 99 (66%) were diagnosed due to symptoms; 61 cases (46%) had delays associated with system factors; of them, 57 (38% of the total) had delayed responses to abnormal findings. Fifteen of the cases (10%) had prompt symptom evaluations but received no CRC screening; no patient factors were identified as potentially contributing to the failure to screen/offer to screen. In total, 97 (65%) of the cases had missed opportunities for early diagnosis and 57 (38%) had patient factors that likely contributed to the diagnostic delay or apparent failure to screen/offer to screen. Conclusion Missed opportunities for earlier CRC diagnosis were frequent. Additional studies of clinical data management, focusing on following

  16. Patient- and system-related barriers for the earlier diagnosis of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Wahls Terry L

    2009-09-01

    Full Text Available Abstract Background A cohort of colorectal cancer (CRC patients represents an opportunity to study missed opportunities for earlier diagnosis. Primary objective: To study the epidemiology of diagnostic delays and failures to offer/complete CRC screening. Secondary objective: To identify system- and patient-related factors that may contribute to diagnostic delays or failures to offer/complete CRC screening. Methods Setting: Rural Veterans Administration (VA Healthcare system. Participants: CRC cases diagnosed within the VA between 1/1/2000 and 3/1/2007. Data sources: progress notes, orders, and pathology, laboratory, and imaging results obtained between 1/1/1995 and 12/31/2007. Completed CRC screening was defined as a fecal occult blood test or flexible sigmoidoscopy (both within five years, or colonoscopy (within 10 years; delayed diagnosis was defined as a gap of more than six months between an abnormal test result and evidence of clinician response. A summary abstract of the antecedent clinical care for each patient was created by a certified gastroenterologist (GI, who jointly reviewed and coded the abstracts with a general internist (TW. Results The study population consisted of 150 CRC cases that met the inclusion criteria. The mean age was 69.04 (range 35-91; 99 (66% were diagnosed due to symptoms; 61 cases (46% had delays associated with system factors; of them, 57 (38% of the total had delayed responses to abnormal findings. Fifteen of the cases (10% had prompt symptom evaluations but received no CRC screening; no patient factors were identified as potentially contributing to the failure to screen/offer to screen. In total, 97 (65% of the cases had missed opportunities for early diagnosis and 57 (38% had patient factors that likely contributed to the diagnostic delay or apparent failure to screen/offer to screen. Conclusion Missed opportunities for earlier CRC diagnosis were frequent. Additional studies of clinical data management

  17. Electronic clinical decision support systems attitudes and barriers to use in the oncology setting.

    LENUS (Irish Health Repository)

    Collins, I M

    2012-03-02

    BACKGROUND: There is little evidence regarding attitudes to clinical decision support systems (CDSS) in oncology. AIMS: We examined the current usage, awareness, and concerns of Irish medical oncologists and oncology pharmacists in this area. METHODS: A questionnaire was sent to 27 medical oncologists and 34 oncology pharmacists, identified through professional interest groups. Respondents ranked concerns regarding their use of a CDSS on a scale from 1 to 4, with 4 being most important. RESULTS: Overall, 67% (41\\/61) responded, 48% (13\\/27) of oncologists and 82% (28\\/34) of pharmacists surveyed. Concerns included "difficulty defining complex clinical situations with a set of rules" (mean ± SD) (3.2 ± 0.9), "ensuring evidence base is up to date and relevant" (3.2 ± 0.9) and "lack of clinically relevant suggestions" (2.9 ± 0.9). Ninety-three percent reported using a CDSS but 54% were unaware of this. CONCLUSION: While there are benefits to using a CDSS, concerns must be addressed through user education. This may be a starting point for a user-centred design approach to the development of future local systems through a consultative process.

  18. Multi-Input Converter with MPPT Feature for Wind-PV Power Generation System

    Directory of Open Access Journals (Sweden)

    Chih-Lung Shen

    2013-01-01

    Full Text Available A multi-input converter (MIC to process wind-PV power is proposed, designed, analyzed, simulated, and implemented. The MIC cannot only process solar energy but deal with wind power, of which structure is derived from forward-type DC/DC converter to step-down/up voltage for charger systems, DC distribution applications, or grid connection. The MIC comprises an upper modified double-ended forward, a lower modified double-ended forward, a common output inductor, and a DSP-based system controller. The two modified double-ended forwards can operate individually or simultaneously so as to accommodate the variation of the hybrid renewable energy under different atmospheric conditions. While the MIC operates at interleaving mode, better performance can be achieved and volume also is reduced. The proposed MIC is capable of recycling the energy stored in the leakage inductance and obtaining high step-up output voltage. In order to draw maximum power from wind turbine and PV panel, perturb-and-observe method is adopted to achieve maximum power point tracking (MPPT feature. The MIC is constructed, analyzed, simulated, and tested. Simulations and hardware measurements have demonstrated the feasibility and functionality of the proposed multi-input converter.

  19. Registration Combining Wide and Narrow Baseline Feature Tracking Techniques for Markerless AR Systems

    Directory of Open Access Journals (Sweden)

    Bo Yang

    2009-12-01

    Full Text Available Augmented reality (AR is a field of computer research which deals with the combination of real world and computer generated data. Registration is one of the most difficult problems currently limiting the usability of AR systems. In this paper, we propose a novel natural feature tracking based registration method for AR applications. The proposed method has following advantages: (1 it is simple and efficient, as no man-made markers are needed for both indoor and outdoor AR applications; moreover, it can work with arbitrary geometric shapes including planar, near planar and non planar structures which really enhance the usability of AR systems. (2 Thanks to the reduced SIFT based augmented optical flow tracker, the virtual scene can still be augmented on the specified areas even under the circumstances of occlusion and large changes in viewpoint during the entire process. (3 It is easy to use, because the adaptive classification tree based matching strategy can give us fast and accurate initialization, even when the initial camera is different from the reference image to a large degree. Experimental evaluations validate the performance of the proposed method for online pose tracking and augmentation.

  20. EEG-Based BCI System Using Adaptive Features Extraction and Classification Procedures

    Directory of Open Access Journals (Sweden)

    Valeria Mondini

    2016-01-01

    Full Text Available Motor imagery is a common control strategy in EEG-based brain-computer interfaces (BCIs. However, voluntary control of sensorimotor (SMR rhythms by imagining a movement can be skilful and unintuitive and usually requires a varying amount of user training. To boost the training process, a whole class of BCI systems have been proposed, providing feedback as early as possible while continuously adapting the underlying classifier model. The present work describes a cue-paced, EEG-based BCI system using motor imagery that falls within the category of the previously mentioned ones. Specifically, our adaptive strategy includes a simple scheme based on a common spatial pattern (CSP method and support vector machine (SVM classification. The system’s efficacy was proved by online testing on 10 healthy participants. In addition, we suggest some features we implemented to improve a system’s “flexibility” and “customizability,” namely, (i a flexible training session, (ii an unbalancing in the training conditions, and (iii the use of adaptive thresholds when giving feedback.

  1. Comparative analysis of kill probability one of the main features of Air Defense Integrated Systems

    Directory of Open Access Journals (Sweden)

    Vasile SANDRU

    2014-09-01

    Full Text Available The combat features of the Ground Based Air Defence Systems represent the potential of search, discovery, indicate, combat and destruction of the enemy's air assets and the ability to manoeuvre of forces and combat means, for the purpose of capturing the enemy's airspace and avoid actions and attack to defend objectives (of troops assigned in the area of responsibility tacking into account the conditions established by the mission. The paper is focused on a comparative study on the possibilities of target destruction of the Air Air Defence Systems (antiaircraft artillery and Surface-To-Air Missiles. Two situations were chosen: for the first case, related to S1, S2 and S3, we’ve assumed the presence of a flying target describing a uniform rectilinear trajectory both in the presence and in the absence of the enemy’s electronic jamming. For the second case concerning S4 we’ve assumed that the target changed its angle of flight.

  2. Clinicopathological and immunohistochemical features of primary central nervous system germ cell tumors: a 24-years experience.

    Science.gov (United States)

    Gao, Yuping; Jiang, Jiyao; Liu, Qiang

    2014-01-01

    Primary central nervous system (CNS) germ cell tumors (GCTs) are a rare heterogeneous group of lesions, which the clinicopathological features have a marked degree of heterogeneity comparing with that of gonadal GCTs. Accurately diagnosing CNS GCTs might be extremely difficult and requires immunohistochemical verification. This study was to investigate the biological feature of CNS GCTs and diagnostic value of immunohistochemical markers OCT3/4, C-kit, PLAP, and CD30 in CNS GCTs. A retrospective study was performed on 34 patients with CNS germ cell tumors between 1990 and 2014. 34 CNS GCTs account for 9.2% of all primary CNS neoplasms. The sellar region (35.3%) and pineal gland (17.6%) were the most common sites of intracranial GCTs. Hydrocephalus (82.4%) and diplopia (46.9%) were the two most common clinical presentations. The most common histological subtypes were germinoma (67.6%). PLAP, c-kit, OCT3/4 were highly expressed in gernimomas. CD30 and CK AE1/3 stainings were positive in embryonal carcinoma. Yolk sac tumor component showed positive staining for AFP and CK AE1/3. β-HCG staining was positive in choriocarcinoma and STGC. Patients with mature teratomas and germinomas had a better prognosis (a 5-year survival rate) than those with embryonal carcinoma and choriocarcinoma (a 5-year survival rates were 0). Our finding suggest that the incidences of primary CNS GCTs are higher in South China than in the West, but mixed GCTs are uncommon in our study. The judicious use of a panel of selected markers is helpful in diagnosing and predicting the prognosis for CNS GCTs.

  3. Subseasonal features of the Asian summer monsoon in the NCEP climate forecast system

    Institute of Scientific and Technical Information of China (English)

    Song YANG; WEN Min; R Wayne HIGGINS

    2008-01-01

    The operational climate forecast system (CFS) of the US National Centers for Environmental Prediction provides climate predic-tions over the world, and CFS products are becoming an important source of information for regional climate predictions in many Asian countries where monsoon climate dominates. Recent studies have shown that, on monthly-to-seasonal time-scales, the CFS is highly skillful in simulating and predicting the variability of the Asian monsoon. The higher-frequency variability of the Asian summer monsoon in the CFS is analyzed, using output from a version with a spectral triangular truncation of 126 waves in horizon-tal and 64 sigma layers in vertical, focusing on synoptic, quasi-biweekly, and intraseasonal time-scales. The onset processes of different regional monsoon components were investigated within Asia. Although the CFS generally overestimates variability of mon-soon on these time-scales, it successfully captures many major features of the variance patterns, especially for the synoptic time-scale. The CFS also captures the timing of summer monsoon onsets over India and the Indo-China Peninsula. However, it encoun-ters difficulties in simulating the onset of the South China Sea monsoon. The success and failure of the CFS in simulating the onset of monsoon precipitation can also be seen from the associated features of simulated atmospheric circulation processes. Overall, the CFS is capable of simulating the synoptic-to-intraseasonal variability of the Asian summer monsoon with skills. As for seasonal-to-interannual time-scales shown previously, the model is expected to possess a potential for skillful predictions of the high-frequencyvariability of the Asian monsoon.

  4. Deep repository - Engineered barrier system. Erosion and sealing processes in tunnel backfill materials investigated in laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Sanden, Torbjoern; Boergesson, Lennart; Dueck, Ann; Goudarzi, Reza; Loennqvist, Margareta (Clay Technology AB, Lund (Sweden))

    2008-12-15

    an additional test series have been performed. These additional tests examined the influence of fine clay material mixed with the pellets, a topic not previously examined. These tests showed that the powder had strong influence on the erosion rate during the first 24 hours of water flow but after that time period the erosion rate was unaffected by the presence of fines. The investigation of how backfill blocks move when water enter slots between them produced predictable results. Two types of tests were performed; in one the displacement was measured and in the other the development of swelling pressure as physically constrained blocks attempted to separate was monitored. In the course of these tests the influence of the initial slot width is determined to be very strong. The majority of the tests were done using Friedland clay blocks. In these tests water influx to a small initial slot resulted in rather large movements, with deformation starting immediately. A large initial slot resulted in smaller overall movement with deformation not starting until about 1.5-2 days after test start. Tests done using Asha 230 behaved in a manner similar to the Friedland blocks, but those made of the 30/70 mixture showed no movement. The self-sealing ability of MX-80 pellets was tested and showed that a water flow of 0.01 l/min and 0.1 l/min through a volume filled with MX-80 pellets will result in transport of fine material within the water and these fines subsequently swell and seal slots with an aperture up to 150 mum. The sealing ability of a saturated backfill after a simulated piping scenario was also tested. After three weeks of healing of an intentionally installed piping feature that had been given access to water, the hydraulic conductivity was measured again. The specimens made of Friedland and Asha 230 showed a very strong ability to seal the hole while the 30/70 mixture couldn't seal the drilled hole at all. MX-80 pellets installed at a dry bulk density

  5. Sustainable fuel, food, fertilizer and ecosystems through a global artificial photosynthetic system: overcoming anticompetitive barriers

    Science.gov (United States)

    Bruce, Alex; Faunce, Thomas

    2015-01-01

    This article discusses challenges that artificial photosynthetic (AP) systems will face when entering and competing in a global market characterized by established fossil fuel technology. It provides a perspective on the neoliberal principles underpinning much policy entrenching such environmentally destructive technology and outlines how competition law could aid overcoming these hurdles for AP development. In particular, it critiques the potential for competition law to promote a global AP initiative with greater emphasis on atmospheric carbon dioxide and nitrogen fixation (as well as solar-driven water splitting) to produce an equitable, globally distributed source of human food, fertilizer and biosphere sustainability, as well as hydrogen-based fuel. Some relevant strategies of competition law evaluated in this context include greater citizen–consumer involvement in shaping market values, legal requirements to factor services from the natural environment (i.e. provision of clean air, water, soil pollution degradation) into corporate costs, reform of corporate taxation and requirements to balance maximization of shareholder profit with contribution to a nominated public good, a global financial transactions tax, as well as prohibiting horizontal cartels, vertical agreements and unilateral misuse of market power. PMID:26052427

  6. One-dimensional free-energy profiles of complex systems: progress variables that preserve the barriers.

    Science.gov (United States)

    Krivov, Sergei V; Karplus, Martin

    2006-06-29

    We show that the balanced minimum-cut procedure introduced in PNAS 2004, 101, 14766 can be reinterpreted as a method for solving the constrained optimization problem of finding the minimum cut among the cuts with a particular value of an additive function of the nodes on either side of the cut. Such an additive function (e.g., the partition function of the reactant region) can be used as a progress coordinate to determine a one-dimensional profile (FEP) of the free-energy surface of the protein-folding reaction as well as other complex reactions. The algorithm is based on the network (obtained from an equilibrium molecular dynamics simulation) that represents the calculated reaction behavior. The resulting FEP gives the exact values of the free energy as a function of the progress coordinate; i.e., at each value of the progress coordinate, the profile is obtained from the surface with the minimal partition function among the surfaces that divide the full free-energy surface between two chosen end points. In many cases, the balanced minimum-cut procedure gives results for only a limited set of points. An approximate method based on p(fold) is shown to provide the profile for a more complete set of values of the progress coordinate. Applications of the approach to model problems and to realistic systems (beta-hairpin of protein G, LJ38 cluster) are presented.

  7. Epithelial barrier: an interface for the cross-communication between gut flora and immune system.

    Science.gov (United States)

    Goto, Yoshiyuki; Kiyono, Hiroshi

    2012-01-01

    Large numbers of environmental antigens, including commensal bacteria and food-derived antigens, constitutively interact with the epithelial layer of the gastrointestinal (GI) tract. Commensal bacteria peacefully cohabit with the host GI tract and exert multiple beneficial or destructive effects on their host. Intestinal epithelial cells (IECs) constitute the first physical and immunological protective wall against invasive pathogens and a cohabitation niche for commensal bacteria. As the physiological homeostasis of IECs is maintained by multiple biological processes such as apoptosis, autophagy, and the handling of endoplasmic reticulum stress, the aberrant kinetics of these biological events, which have genetic and environmental causes, leads to the development of host intestinal pathogenesis such as inflammatory bowel disease. In addition, IECs recognize and interact with commensal bacteria and give instructions to mucosal immune cells to initiate an immunological balance between active and quiescent conditions, eventually establishing intestinal homeostasis. The mucosal immune system regulates the homeostasis of gut microbiota by producing immunological molecules such as secretory immunoglobulin A, the production of which is mediated by IECs. IECs therefore play a central role in the creation and maintenance of a physiologically and immunologically stable intestinal environment.

  8. Sustainable fuel, food, fertilizer and ecosystems through a global artificial photosynthetic system: overcoming anticompetitive barriers.

    Science.gov (United States)

    Bruce, Alex; Faunce, Thomas

    2015-06-06

    This article discusses challenges that artificial photosynthetic (AP) systems will face when entering and competing in a global market characterized by established fossil fuel technology. It provides a perspective on the neoliberal principles underpinning much policy entrenching such environmentally destructive technology and outlines how competition law could aid overcoming these hurdles for AP development. In particular, it critiques the potential for competition law to promote a global AP initiative with greater emphasis on atmospheric carbon dioxide and nitrogen fixation (as well as solar-driven water splitting) to produce an equitable, globally distributed source of human food, fertilizer and biosphere sustainability, as well as hydrogen-based fuel. Some relevant strategies of competition law evaluated in this context include greater citizen-consumer involvement in shaping market values, legal requirements to factor services from the natural environment (i.e. provision of clean air, water, soil pollution degradation) into corporate costs, reform of corporate taxation and requirements to balance maximization of shareholder profit with contribution to a nominated public good, a global financial transactions tax, as well as prohibiting horizontal cartels, vertical agreements and unilateral misuse of market power.

  9. Residual Stresses in Thermal Barrier Coatings for a Cu-8Cr-4Nb Substrate System

    Science.gov (United States)

    Ghosn, Louis J.; Raj, Sai V.

    2002-01-01

    Analytical calculations were conducted to determine the thermal stresses developed in a coated copper-based alloy, Cu-8%(at.%)Cr-4%Nb (designated as GRCop-84), after plasma spraying and during heat-up in a simulated rocket engine environment. Finite element analyses were conducted for two coating systems consisting of a metallic top coat, a pure copper bond coat and the GRCop-84. The through thickness temperature variations were determined as a function of coating thickness for two metallic coatings, a Ni-17%(wt%)Cr-6%Al-0.5%Y alloy and a Ni-50%(at.%)Al alloy. The residual stresses after low-pressure plasma spraying of the NiCrAlY and NiAl coatings on GRCop-84 substrate were also evaluated. These analyses took into consideration a 50.8 mm copper bond coat and the effects of an interface coating roughness. The through the thickness thermal stresses developed in coated liners were also calculated after 15 minutes of exposure in a rocket environment with and without an interfacial roughness.

  10. C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus.

    Science.gov (United States)

    Mahajan, Supriya D; Parikh, Neil U; Woodruff, Trent M; Jarvis, James N; Lopez, Molly; Hennon, Teresa; Cunningham, Patrick; Quigg, Richard J; Schwartz, Stanley A; Alexander, Jessy J

    2015-09-01

    The blood-brain barrier (BBB) plays a crucial role in brain homeostasis, thereby maintaining the brain environment precise for optimal neuronal function. Its dysfunction is an intriguing complication of systemic lupus erythematosus (SLE). SLE is a systemic autoimmune disorder where neurological complications occur in 5-50% of cases and is associated with impaired BBB integrity. Complement activation occurs in SLE and is an important part of the clinical profile. Our earlier studies demonstrated that C5a generated by complement activation caused the loss of brain endothelial layer integrity in rodents. The goal of the current study was to determine the translational potential of these studies to a human system. To assess this, we used a two dimensional in vitro BBB model constructed using primary human brain microvascular endothelial cells and astroglial cells, which closely emulates the in vivo BBB allowing the assessment of BBB integrity. Increased permeability monitored by changes in transendothelial electrical resistance and cytoskeletal remodelling caused by actin fiber rearrangement were observed when the cells were exposed to lupus serum and C5a, similar to the observations in mice. In addition, our data show that C5a/C5aR1 signalling alters nuclear factor-κB translocation into nucleus and regulates the expression of the tight junction proteins, claudin-5 and zonula occludens 1 in this setting. Our results demonstrate for the first time that C5a regulates BBB integrity in a neuroinflammatory setting where it affects both endothelial and astroglial cells. In addition, we also demonstrate that our previous findings in a mouse model, were emulated in human cells in vitro, bringing the studies one step closer to understanding the translational potential of C5a/C5aR1 blockade as a promising therapeutic strategy in SLE and other neurodegenerative diseases.

  11. Parentification in late adolescence and selected features of the family system

    Directory of Open Access Journals (Sweden)

    Judyta Borchet

    2015-12-01

    Full Text Available Background Parentification is a pattern of family interactions when either a child or an adolescent accepts roles and obligations fulfilled by adults. Being burdened with duties and taking care of parents makes separation, as well as fulfilment of development tasks and acceptance of roles suitable for a child, difficult. Simultaneously parentification might constitute a factor which forms resilience and functional coping manners. The aim of the study was to broaden the knowledge about parentification and its connections with the features of the family system. Participants and procedure The participants were 89 people divided into triads including the youngster in his/her late teens and his/her parents. The youngsters filled in Hooper’s Parentification Inventory and Olson’s Family Evaluation Scale (FES, in Margasiński’s adaptation, and assessed the bond with family members using a drawing scale. The parents also filled in the FES, and additionally they evaluated the level of conflict intensity and tension in a partner relationship by means of a modified version of the Cantril Ladder. Results Perception of the benefits of parentification differentiated the adolescents from well-balanced and ill-balanced families. Additionally, the stronger the bond the adolescents shared with their parents and the higher they assessed their satisfaction with family life and communications in the family, the more positive was their view of the effects of parentification. The predictor for the perception of the benefits of parentification by adolescents turned out to be the family’s cohesion. Conclusions The assessment of the functioning of the family system is essential. When, according to adolescents, the family system is functioning effectively, they can use the family resources and positively reformulate even negative experiences concerned with parentification.

  12. The locomotory system of pearlfish Carapus acus: what morphological features are characteristic for highly flexible fishes?

    Science.gov (United States)

    Schwarz, Cathrin; Parmentier, Eric; Wiehr, Stefan; Gemballa, Sven

    2012-05-01

    The body curvature displayed by fishes differs remarkably between species. Some nonmuscular features (e.g., number of vertebrae) are known to influence axial flexibility, but we have poor knowledge of the influence of the musculotendinous system (myosepta and muscles). Whereas this system has been described in stiff-bodied fishes, we have little data on flexible fishes. In this study, we present new data on the musculotendinous system of a highly flexible fish and compare them to existing data on rigid fishes. We use microdissections with polarized light microscopy to study the three-dimensional anatomy of myoseptal tendons, histology and immunohistology to study the insertion of muscle fiber types into tendons, and μ-CT scans to study skeletal anatomy. Results are compared with published data from stiff-bodied fishes. We identify four important morphological differences between stiff-bodied fishes and Carapus acus: (1) Carapus bears short tendons in the horizontal septum, whereas rigid fishes have elongated tendons. (2) Carapus bears short lateral tendons in its myosepta, whereas stiff-bodied fishes bear elongated tendons. Because of its short myoseptal tendons, Carapus retains high axial flexibility. In contrast, elongated tendons restrict axial flexibility in rigid fishes but are able to transmit anteriorly generated muscle forces through long tendons down to the tail. (3) Carapus bears distinct epineural and epipleural tendons in its myosepta, whereas these tendons are weak or absent in rigid fishes. As these tendons firmly connect vertebral axis and skin in Carapus, we consider them to constrain lateral displacement of the vertebral axis during extreme body flexures. (4) Ossifications of myoseptal tendons are only present in C. acus and other more flexible fishes but are absent in rigid fishes. The functional reasons for this remain unexplained.

  13. Identifying the Barriers to Women's Agency in Domestic Violence: The Tensions between Women's Personal Experiences and Systemic Responses

    Directory of Open Access Journals (Sweden)

    Jo Aldridge

    2013-04-01

    Full Text Available Despite advances in knowledge and understanding about the impacts of domestic violence on women's lives, global research on violence against women shows there is a need for research that not only places women centre stage in research praxis, but also that involves them more collaboratively in genuine dialogue about their experiences, including their agentic stances. This is especially the case for marginalised and socially excluded women victims of domestic violence, such as those who are not known or do not present to services and who survive abusive relationships alone or with little outside support. Evidence from two studies reported here—secondary analysis of women with severe and enduring mental health problems and a collaborative narrative project with unsupported women victims of domestic violence—suggest that women's capacity for agency are compromised by a number of critical factors, and that these are also reflected in the tensions between micro–macro analyses and understanding of the impact of domestic violence on women. This article considers the barriers to women's agency from the women's perspective and in the context of broader, systemic dynamics, including the denial or obscuring of abuse by governments and states and the consequences of stringent fiscal retrenchment that put women at increased risk of domestic violence.

  14. Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

    Science.gov (United States)

    Vernetti, Lawrence; Gough, Albert; Baetz, Nicholas; Blutt, Sarah; Broughman, James R.; Brown, Jacquelyn A.; Foulke-Abel, Jennifer; Hasan, Nesrin; In, Julie; Kelly, Edward; Kovbasnjuk, Olga; Repper, Jonathan; Senutovitch, Nina; Stabb, Janet; Yeung, Catherine; Zachos, Nick C.; Donowitz, Mark; Estes, Mary; Himmelfarb, Jonathan; Truskey, George; Wikswo, John P.; Taylor, D. Lansing

    2017-01-01

    Organ interactions resulting from drug, metabolite or xenobiotic transport between organs are key components of human metabolism that impact therapeutic action and toxic side effects. Preclinical animal testing often fails to predict adverse outcomes arising from sequential, multi-organ metabolism of drugs and xenobiotics. Human microphysiological systems (MPS) can model these interactions and are predicted to dramatically improve the efficiency of the drug development process. In this study, five human MPS models were evaluated for functional coupling, defined as the determination of organ interactions via an in vivo-like sequential, organ-to-organ transfer of media. MPS models representing the major absorption, metabolism and clearance organs (the jejunum, liver and kidney) were evaluated, along with skeletal muscle and neurovascular models. Three compounds were evaluated for organ-specific processing: terfenadine for pharmacokinetics (PK) and toxicity; trimethylamine (TMA) as a potentially toxic microbiome metabolite; and vitamin D3. We show that the organ-specific processing of these compounds was consistent with clinical data, and discovered that trimethylamine-N-oxide (TMAO) crosses the blood-brain barrier. These studies demonstrate the potential of human MPS for multi-organ toxicity and absorption, distribution, metabolism and excretion (ADME), provide guidance for physically coupling MPS, and offer an approach to coupling MPS with distinct media and perfusion requirements. PMID:28176881

  15. Feasibility study of a single-element transcranial focused ultrasound system for blood-brain barrier opening

    Science.gov (United States)

    Marquet, Fabrice; Tung, Yao-Sheng; Teichert, Tobias; Ferrera, Vincent P.; Konofagou, Elisa E.

    2012-10-01

    The blood-brain barrier (BBB) is a specialized vascular system that impedes entry of all large and the vast majority of small molecules including the most potent CNS disease therapeutic agents from entering from the lumen into the brain parenchyma. Microbubble-enhanced, focused ultrasound (ME-FUS) has been previously shown to disrupt noninvasively, selectively, and transiently the BBB in small animals in vivo. The study addresses the focusing properties of single-element transducers at intermediate frequencies (500 kHz) through primate and human skulls, targeting clinically relevant targets extracted from 3D brain atlases such as the hippocampus and the basal ganglia, which are typically affected by early Alzheimer's and Parkinson's disease, respectively. A preliminary in vivo study was performed to study the frequency dependence of BBB opening parameters in mice. Then, feasibility of transcranial ME-FUS BBB opening in non-human primates was demonstrated with subsequent BBB recovery. Sonications were combined with two different types of microbubbles (custom made 4-5 μm and Definity®). 3T MRI was used to confirm the BBB disruption and to assess brain damage.

  16. Exploring barriers to participation and adoption of telehealth and telecare within the Whole System Demonstrator trial: a qualitative study

    Directory of Open Access Journals (Sweden)

    Sanders Caroline

    2012-07-01

    Full Text Available Abstract Background Telehealth (TH and telecare (TC interventions are increasingly valued for supporting self-care in ageing populations; however, evaluation studies often report high rates of non-participation that are not well understood. This paper reports from a qualitative study nested within a large randomised controlled trial in the UK: the Whole System Demonstrator (WSD project. It explores barriers to participation and adoption of TH and TC from the perspective of people who declined to participate or withdrew from the trial. Methods Qualitative semi-structured interviews were conducted with 22 people who declined to participate in the trial following explanations of the intervention (n = 19, or who withdrew from the intervention arm (n = 3. Participants were recruited from the four trial groups (with diabetes, chronic obstructive pulmonary disease, heart failure, or social care needs; and all came from the three trial areas (Cornwall, Kent, east London. Observations of home visits where the trial and interventions were first explained were also conducted by shadowing 8 members of health and social care staff visiting 23 people at home. Field notes were made of observational visits and explored alongside interview transcripts to elicit key themes. Results Barriers to adoption of TH and TC associated with non-participation and withdrawal from the trial were identified within the following themes: requirements for technical competence and operation of equipment; threats to identity, independence and self-care; expectations and experiences of disruption to services. Respondents held concerns that special skills were needed to operate equipment but these were often based on misunderstandings. Respondents’ views were often explained in terms of potential threats to identity associated with positive ageing and self-reliance, and views that interventions could undermine self-care and coping. Finally, participants were reluctant to

  17. Does the choice of display system influence perception and visibility of clinically relevant features in digital pathology images?

    Science.gov (United States)

    Kimpe, Tom; Rostang, Johan; Avanaki, Ali; Espig, Kathryn; Xthona, Albert; Cocuranu, Ioan; Parwani, Anil V.; Pantanowitz, Liron

    2014-03-01

    Digital pathology systems typically consist of a slide scanner, processing software, visualization software, and finally a workstation with display for visualization of the digital slide images. This paper studies whether digital pathology images can look different when presenting them on different display systems, and whether these visual differences can result in different perceived contrast of clinically relevant features. By analyzing a set of four digital pathology images of different subspecialties on three different display systems, it was concluded that pathology images look different when visualized on different display systems. The importance of these visual differences is elucidated when they are located in areas of the digital slide that contain clinically relevant features. Based on a calculation of dE2000 differences between background and clinically relevant features, it was clear that perceived contrast of clinically relevant features is influenced by the choice of display system. Furthermore, it seems that the specific calibration target chosen for the display system has an important effect on the perceived contrast of clinically relevant features. Preliminary results suggest that calibrating to DICOM GSDF calibration performed slightly worse than sRGB, while a new experimental calibration target CSDF performed better than both DICOM GSDF and sRGB. This result is promising as it suggests that further research work could lead to better definition of an optimized calibration target for digital pathology images resulting in a positive effect on clinical performance.

  18. Features and states of microscopic particles in nonlinear quantum-mechanics systems

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In this paper,we present the elementary principles of nonlinear quantum mechanics(NLQM),which is based on some problems in quantum mechanics.We investigate in detail the motion laws and some main properties of microscopic particles in nonlinear quantum systems using these elementary principles.Concretely speaking,we study in this paper the wave-particle duality of the solution of the nonlinear Schr6dinger equation,the stability of microscopic particles described by NLQM,invariances and conservation laws of motion of particles,the Hamiltonian principle of particle motion and corresponding Lagrangian and Hamilton equations,the classical rule of microscopic particle motion,the mechanism and rules of particle collision,the features of reflection and the transmission of particles at interfaces,and the uncertainty relation of particle motion as well as the eigenvalue and eigenequations of particles,and so on.We obtained the invariance and conservation laws of mass,energy and momentum and angular momenturn for the microscopic particles,which are also some elementary and universal laws of matter in the NLQM and give further the methods and ways of solving the above questions.We also find that the laws of motion of microscopic particles in such a case are completely different from that in the linear quantum mechanics(LQM).They have a lot of new properties;for example,the particles possess the real wave-corpuscle duality,obey the classical rule of motion and conservation laws of energy,momentum and mass,satisfy minimum uncertainty relation,can be localized due to the nonlinear interaction,and its position and momentum can also be determined,etc.From these studies,we see clearly that rules and features of microscopic particle motion in NLQM is different from that in LQM.Therefore,the NLQM is a new physical theory,and a necessary result of the development of quantum mechanics and has a correct representation of describing microscopic particles in nonlinear systems,which can

  19. Potential structural barriers to ground-water flow, Death Valley regional ground-water flow system, Nevada and California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the surface traces of regional geologic structures designated as potential ground-water flow barriers in an approximately 45,000...

  20. A FEATURE SELECTION ALGORITHM DESIGN AND ITS IMPLEMENTATION IN INTRUSION DETECTION SYSTEM

    Institute of Scientific and Technical Information of China (English)

    杨向荣; 沈钧毅

    2003-01-01

    Objective Present a new features selection algorithm. Methods based on rule induction and field knowledge. Results This algorithm can be applied in catching dataflow when detecting network intrusions, only the sub-dataset including discriminating features is catched. Then the time spend in following behavior patterns mining is reduced and the patterns mined are more precise. Conclusion The experiment results show that the feature subset catched by this algorithm is more informative and the dataset's quantity is reduced significantly.

  1. Downlink Radio Resource Management for LTE-Advanced System with Combined MU-MIMO and Carrier Aggregation Features

    DEFF Research Database (Denmark)

    Nguyen, Hung Tuan; Kovacs, Istvan

    2012-01-01

    In this paper we study the performance enhancement of a downlink LTE-Advanced system with a combination of the multi-user MIMO and carrier aggregation transmission techniques. Radio resource management for the systems with the combined features are proposed, and the system performance is evaluate...... that MU-MIMO transmission technique can help to enhance the cell-edge performance of the CA system by 10%-40% depending on traffic load....

  2. Barriers in access to healthcare in countries with different health systems. A cross-sectional study in municipalities of central Colombia and north-eastern Brazil.

    Science.gov (United States)

    Garcia-Subirats, Irene; Vargas, Ingrid; Mogollón-Pérez, Amparo Susana; De Paepe, Pierre; da Silva, Maria Rejane Ferreira; Unger, Jean Pierre; Vázquez, María Luisa

    2014-04-01

    There are few comprehensive studies available on barriers encountered from the initial seeking of healthcare through to the resolution of the health problem; in other words, on access in its broad domain. For Colombia and Brazil, countries with different healthcare systems but common stated principles, there have been no such analyses to date. This paper compares factors that influence access in its broad domain in two municipalities of each country, by means of a cross-sectional study based on a survey of a multistage probability sample of people who had had at least one health problem within the last three months (2163 in Colombia and 2155 in Brazil). The results reveal important barriers to healthcare access in both samples, with notable differences between and within countries, once differences in sociodemographic characteristics and health needs are accounted for. In the Colombian study areas, the greatest barriers were encountered in initial access to healthcare and in resolving the problem, and similarly when entering the health service in the Brazilian study areas. Differences can also be detected in the use of services: in Colombia greater geographical and economic barriers and the need for authorization from insurers are more relevant, whereas in Brazil, it is the limited availability of health centres, doctors and drugs that leads to longer waiting times. There are also differences according to enrolment status and insurance scheme in Colombia, and between areas in Brazil. The barriers appear to be related to the Colombian system's segmented, non-universal nature, and to the involvement of insurance companies, and to chronic underfunding of the public system in Brazil. Further research is required, but the results obtained reveal critical points to be tackled by health policies in both countries.

  3. Feature Article: Understanding strongly correlated many-body systems with quantum Monte Carlo simulations

    Science.gov (United States)

    Lavalle, Catia; Rigol, Marcos; Muramatsu, Alejandro

    2005-08-01

    The cover picture of the current issue, taken from the Feature Article [1], depicts the evolution of local density (a) and its quantum fluctuations (b) in trapped fermions on one-dimensional optical lattices. As the number of fermions in the trap is increased, figure (a) shows the formation of a Mott-insulating plateau (local density equal to one) whereas the quantum fluctuations - see figure (b) - are strongly suppressed, but nonzero. For a larger number of fermions new insulating plateaus appear (this time with local density equal to two), but no density fluctuations. Regions with non-constant density are metallic and exhibit large quantum fluctuations of the density.The first author Catia Lavalle is a Postdoc at the University of Stuttgart. She works in the field of strongly correlated quantum systems by means of Quantum Monte Carlo methods (QMC). While working on her PhD thesis at the University of Stuttgart, she developed a new QMC technique that allows to study dynamical properties of the t-J model.

  4. Some Quantum-Like Features of Mass Politics in Two-Party Systems

    CERN Document Server

    Smith, Charles E

    2011-01-01

    We expand the substantive terrain of QI's reach by illuminating a body of political theory that to date has been elaborated in strictly classical language and formalisms but has complex features that seem to merit generalizations of the problem outside the confines of classicality. The line of research, initiated by Fiorina in the 1980s, seeks to understand the origins and nature of party governance in two-party political systems wherein voters cast partisan ballots in two contests, one that determines partisan control of the executive branch and another that determines party control of a legislature. We describe how research in this area evolved in the last two decades in directions that bring it now to the point where further elaboration and study seem natural in the more general formalistic and philosophical environments embraced in QI research. In the process, we find evidence that a restriction of a classical model that has animated work in the field appears violated in a form that leads one naturally to...

  5. Patterns and singular features of extreme fluctuational paths of a periodically driven system

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Zhen, E-mail: czkillua@icloud.com; Liu, Xianbin, E-mail: xbliu@nuaa.edu.cn

    2016-05-20

    Large fluctuations of an overdamped periodically driven oscillating system are investigated theoretically and numerically in the limit of weak noise. Optimal paths fluctuating to certain point are given by statistical analysis using the concept of prehistory probability distribution. The validity of statistical results is verified by solutions of boundary value problem. Optimal paths are found to change topologically when terminating points lie at opposite side of a switching line. Patterns of extreme paths are plotted through a proper parameterization of Lagrangian manifold having complicated structures. Several extreme paths to the same point are obtained by multiple solutions of boundary value solutions. Actions along various extreme paths are calculated and associated analysis is performed in relation to the singular features of the patterns. - Highlights: • Both extreme and optimal paths are obtained by various methods. • Boundary value problems are solved to ensure the validity of statistical results. • Topological structure of Lagrangian manifold is considered. • Singularities of the pattern of extreme paths are studied.

  6. Clinical and laboratory features of systemic sclerosis complicated with localized scleroderma.

    Science.gov (United States)

    Toki, Sayaka; Motegi, Sei-ichiro; Yamada, Kazuya; Uchiyama, Akihiko; Kanai, Sahori; Yamanaka, Masayoshi; Ishikawa, Osamu

    2015-03-01

    Localized scleroderma (LSc) primarily affects skin, whereas systemic sclerosis (SSc) affects skin and various internal organs. LSc and SSc are considered to be basically different diseases, and there is no transition between them. However, LSc and SSc have several common characteristics, including endothelial cell dysfunction, immune activation, and excess fibrosis of the skin, and there exist several SSc cases complicated with LSc during the course of SSc. Clinical and laboratory characteristics of SSc patients with LSc remain unclear. We investigated the clinical and laboratory features of 8 SSc patients with LSc among 220 SSc patients (3.6%). The types of LSc included plaque (5/8), guttate (2/8), and linear type (1/8). All cases were diagnosed as having SSc within 5 years before or after the appearance of LSc. In three cases of SSc with LSc (37.5%), LSc skin lesions preceded clinical symptoms of SSc. Young age, negative antinuclear antibody, and positive anti-RNA polymerase III antibody were significantly prevalent in SSc patients with LSc. The positivity of anticentromere antibody tended to be prevalent in SSc patients without LSc. No significant difference in the frequency of complications, such as interstitial lung disease, reflux esophagitis, and pulmonary artery hypertension, was observed. The awareness of these characteristic of SSc with LSc are essential to establish an early diagnosis and treatment.

  7. Exploring the elastic features of spherically shaped biological assemblies and soft matter systems

    Energy Technology Data Exchange (ETDEWEB)

    Asfaw, Mesfin, E-mail: mesfin.taye@csun.edu [Department of Physics and Astronomy, California State University, Northridge, CA (United States)

    2011-03-16

    Using a numerical simulation, we study the elastic features of biological assemblies (e.g. viruses and bacteria) and soft matter systems (e.g. colloidosomes and nanoparticle covered droplets) that possess a spherical shape in which the proteins (particles) on the colloidosomes or virus shells are mechanically linked to form a stress-bearing spherical structure that may dramatically enhance the surface rigidity. The dependence of the rigidity enhancement upon the density of the cross-linked proteins situated on the surface of the virus is explored. We determine the percolation threshold P{sub ce} by considering bond percolation on the spherical elastic networks involving nearest neighbor forces. The percolation threshold of such networks is very different from that of a two-dimensional triangular lattice due to the topological effect. We find that the threshold probability for the spherical elastic network is considerably smaller than for an unwrapped network, which reveals that the spherical topology induces more rigidity to the network.

  8. Sensor-based auto-focusing system using multi-scale feature extraction and phase correlation matching.

    Science.gov (United States)

    Jang, Jinbeum; Yoo, Yoonjong; Kim, Jongheon; Paik, Joonki

    2015-03-10

    This paper presents a novel auto-focusing system based on a CMOS sensor containing pixels with different phases. Robust extraction of features in a severely defocused image is the fundamental problem of a phase-difference auto-focusing system. In order to solve this problem, a multi-resolution feature extraction algorithm is proposed. Given the extracted features, the proposed auto-focusing system can provide the ideal focusing position using phase correlation matching. The proposed auto-focusing (AF) algorithm consists of four steps: (i) acquisition of left and right images using AF points in the region-of-interest; (ii) feature extraction in the left image under low illumination and out-of-focus blur; (iii) the generation of two feature images using the phase difference between the left and right images; and (iv) estimation of the phase shifting vector using phase correlation matching. Since the proposed system accurately estimates the phase difference in the out-of-focus blurred image under low illumination, it can provide faster, more robust auto focusing than existing systems.

  9. Sensor-Based Auto-Focusing System Using Multi-Scale Feature Extraction and Phase Correlation Matching

    Directory of Open Access Journals (Sweden)

    Jinbeum Jang

    2015-03-01

    Full Text Available This paper presents a novel auto-focusing system based on a CMOS sensor containing pixels with different phases. Robust extraction of features in a severely defocused image is the fundamental problem of a phase-difference auto-focusing system. In order to solve this problem, a multi-resolution feature extraction algorithm is proposed. Given the extracted features, the proposed auto-focusing system can provide the ideal focusing position using phase correlation matching. The proposed auto-focusing (AF algorithm consists of four steps: (i acquisition of left and right images using AF points in the region-of-interest; (ii feature extraction in the left image under low illumination and out-of-focus blur; (iii the generation of two feature images using the phase difference between the left and right images; and (iv estimation of the phase shifting vector using phase correlation matching. Since the proposed system accurately estimates the phase difference in the out-of-focus blurred image under low illumination, it can provide faster, more robust auto focusing than existing systems.

  10. Feature-based alert correlation in security systems using self organizing maps

    Science.gov (United States)

    Kumar, Munesh; Siddique, Shoaib; Noor, Humera

    2009-04-01

    The security of the networks has been an important concern for any organization. This is especially important for the defense sector as to get unauthorized access to the sensitive information of an organization has been the prime desire for cyber criminals. Many network security techniques like Firewall, VPN Concentrator etc. are deployed at the perimeter of network to deal with attack(s) that occur(s) from exterior of network. But any vulnerability that causes to penetrate the network's perimeter of defense, can exploit the entire network. To deal with such vulnerabilities a system has been evolved with the purpose of generating an alert for any malicious activity triggered against the network and its resources, termed as Intrusion Detection System (IDS). The traditional IDS have still some deficiencies like generating large number of alerts, containing both true and false one etc. By automatically classifying (correlating) various alerts, the high-level analysis of the security status of network can be identified and the job of network security administrator becomes much easier. In this paper we propose to utilize Self Organizing Maps (SOM); an Artificial Neural Network for correlating large amount of logged intrusion alerts based on generic features such as Source/Destination IP Addresses, Port No, Signature ID etc. The different ways in which alerts can be correlated by Artificial Intelligence techniques are also discussed. . We've shown that the strategy described in the paper improves the efficiency of IDS by better correlating the alerts, leading to reduced false positives and increased competence of network administrator.

  11. Building an intrusion detection system using a filter-based feature selection algorithm

    NARCIS (Netherlands)

    Ambusaidi, Mohammed A.; He, Xiangjian; Nanda, Priyadarsi; Tan, Zhiyuan

    2016-01-01

    Redundant and irrelevant features in data have caused a long-term problem in network traffic classification. These features not only slow down the process of classification but also prevent a classifier from making accurate decisions, especially when coping with big data. In this paper, we propose a

  12. Ensemble based system for whole-slide prostate cancer probability mapping using color texture features.

    LENUS (Irish Health Repository)

    DiFranco, Matthew D

    2011-01-01

    We present a tile-based approach for producing clinically relevant probability maps of prostatic carcinoma in histological sections from radical prostatectomy. Our methodology incorporates ensemble learning for feature selection and classification on expert-annotated images. Random forest feature selection performed over varying training sets provides a subset of generalized CIEL*a*b* co-occurrence texture features, while sample selection strategies with minimal constraints reduce training data requirements to achieve reliable results. Ensembles of classifiers are built using expert-annotated tiles from training images, and scores for the probability of cancer presence are calculated from the responses of each classifier in the ensemble. Spatial filtering of tile-based texture features prior to classification results in increased heat-map coherence as well as AUC values of 95% using ensembles of either random forests or support vector machines. Our approach is designed for adaptation to different imaging modalities, image features, and histological decision domains.

  13. Mucocutaneous and demographic features of systemic sclerosis: A profile of 46 patients from Eastern India

    Directory of Open Access Journals (Sweden)

    Sudip Kumar Ghosh

    2012-01-01

    Full Text Available Background: Systemic sclerosis (SSc is a multisystem connective tissue disorder of uncertain etiology. The clinical picture is frequently dominated by prominent cutaneous manifestations that have diagnostic and prognostic significance. The objective of the present study was to find out the demographic profile and the relative frequencies and characteristics of different mucocutaneous features of SSc in a group of patients from eastern India. In addition, we sought to compare the frequency and pattern of the findings in the limited versus the diffuse variety of the disease. Materials and Methods:This was a cross-sectional, clinical observational study. Consecutive patients of SSc attending the dermatology O.P.D. of a tertiary care hospital of eastern India over 3 years were enrolled to the present study. Results:A total of 46 patients (41 females and 5 males; mean age 29.6±12.3 years of SSc were evaluated. Among mucocutaneous manifestations Raynaud′s phenomenon was present in 39 (84.8% patients. Other cutaneous features included dyspigmentation (40, 86.9%, sclerodactyly (38, 82.6%, inability to open the mouth (38,82.6%, mat-like telangiectasia (11,23.1%, fingertip ulceration and scarring (29,63%, cutaneous calcinosis (1,2.2%, digital gangrene in (2,4.3%, generalized pruritus (4,8.7%, cutaneous small vessel vasculitis (2,4.3%, chronic urticaria (2,4.3%, flexion contractures of the fingers (13,28.3%, and amputation of the digits (3,6.5%. Mucosal changes were observed in 10 (21.7% patients and nail changes were seen in 13 (28.2% patients. Diffuse cutaneous SSc was noted in 27 (58.7% patients and limited cutaneous SSc was seen in the remainder. Thirty-six (78.2% patients tested positive for ANA. Conclusion: The present study provides a snapshot of the spectrum of the demographic and mucocutaneous manifestations of SSc in the eastern Indian population. We have not observed any statistically significant differences between dcSSc and lcSSc in terms

  14. Classifying Pediatric Central Nervous System Tumors through near Optimal Feature Selection and Mutual Information: A Single Center Cohort

    Directory of Open Access Journals (Sweden)

    Mohammad Faranoush

    2013-10-01

    Full Text Available Background: Labeling, gathering mutual information, clustering and classificationof central nervous system tumors may assist in predicting not only distinct diagnosesbased on tumor-specific features but also prognosis. This study evaluates the epidemi-ological features of central nervous system tumors in children who referred to Mahak’sPediatric Cancer Treatment and Research Center in Tehran, Iran.Methods: This cohort (convenience sample study comprised 198 children (≤15years old with central nervous system tumors who referred to Mahak's PediatricCancer Treatment and Research Center from 2007 to 2010. In addition to the descriptiveanalyses on epidemiological features and mutual information, we used the LeastSquares Support Vector Machines method in MATLAB software to propose apreliminary predictive model of pediatric central nervous system tumor feature-labelanalysis. Results:Of patients, there were 63.1% males and 36.9% females. Patients' mean±SDage was 6.11±3.65 years. Tumor location was as follows: supra-tentorial (30.3%, infra-tentorial (67.7% and 2% (spinal. The most frequent tumors registered were: high-gradeglioma (supra-tentorial in 36 (59.99% patients and medulloblastoma (infra-tentorialin 65 (48.51% patients. The most prevalent clinical findings included vomiting,headache and impaired vision. Gender, age, ethnicity, tumor stage and the presence ofmetastasis were the features predictive of supra-tentorial tumor histology.Conclusion: Our data agreed with previous reports on the epidemiology of centralnervous system tumors. Our feature-label analysis has shown how presenting features maypartially predict diagnosis. Timely diagnosis and management of central nervous systemtumors can lead to decreased disease burden and improved survival. This may be furtherfacilitated through development of partitioning, risk prediction and prognostic models.

  15. Health system barriers to strengthening vaccine-preventable disease surveillance and response in the context of decentralization: evidence from Georgia

    Directory of Open Access Journals (Sweden)

    Silvestre Eva A

    2006-07-01

    Full Text Available Abstract Background A critical challenge in the health sector in developing countries is to ensure the quality and effectiveness of surveillance and public health response in an environment of decentralization. In Georgia, a country where there has been extensive decentralization of public health responsibilities over the last decade, an intervention was recently piloted to strengthen district-level local vaccine-preventable disease surveillance and response activities through improved capacity to analyze and use routinely collected data. The purpose of the study is 1 to assess the effectiveness of the intervention on motivation and perceived capacity to analyze and use information at the district-level, and 2 to assess the role that individual- and system-level factors play in influencing the effectiveness of the intervention. Methods A pre-post quasi-experimental research design is used for the quantitative evaluation. Data come from a baseline and two follow-up surveys of district-level health staff in 12 intervention and 3 control Center of Public Health (CPH offices. These data were supplemented by record reviews in CPH offices as well as focus group discussions among CPH and health facility staff. Results The results of the study suggest that a number of expected improvements in perceived data availability and analysis occurred following the implementation of the intervention package, and that these improvements in analysis could be attributable to the intervention package. However, the study results also suggest that there exist several health systems barriers that constrained the effectiveness of the intervention in influencing the availability of data, analysis and response. Conclusion To strengthen surveillance and response systems in Georgia, as well as in other countries, donor, governments, and other stakeholders should consider how health systems factors influence investments to improve the availability of data, analysis, and

  16. PS2-13: Implementing a Lean Management System in Primary Care: Facilitators and Barriers from the Frontlines

    Science.gov (United States)

    Hung, Dorothy; Gray, Caroline; Anderson, Katie; Hereford, James

    2013-01-01

    Background/Aims As approximately $750 billion is wasted in the U.S. health system each year, equivalent to roughly one-third of every medical dollar, “Lean” thinking and techniques offer promising solutions for maximizing value in health care. This study examines a large, multispecialty practice’s journey of implementing a Lean management system beginning in primary care. We sought to understand initial drivers and barriers to implementation, with lessons contributing to a learning system of improvement in health care. Methods This case study was based on in-depth interviews with 16 physician and administrative leaders, and 4 focus groups of medical assistants and administrative staff. Transcripts were coded and analyzed using inductive, grounded methodology. Results Respondents’ insights were clustered around three main themes: organizational leadership, professional values/culture, and availability of resources. Informants described organizational characteristics critical to implementing Lean and to which they attributed its success so far, including: strong leadership and the importance that leaders embody qualities they are espousing, willingness to engage all levels of staff in the change process, and willingness to adjust performance measures according to new job roles. However, many noted that values and norms surrounding clinical practice are often at odds with the Lean principle of standardizing work to eliminate waste, representing the biggest challenge for physicians who are socialized into a culture where independent thinking and autonomy is valued. The availability of resources was also cited as an important factor in executing changes, including time to do one’s regular work while implementing change, time to absorb new ideas and changes, and proper space configurations to support the change. Conclusions Lean represents a non-traditional approach to managing the delivery of medical care. In a Lean operating system, value is seen first from

  17. Opportunities for functional oxides in yttrium oxide-titanium oxide-zirconium oxide system: Applications for novel thermal barrier coatings

    Science.gov (United States)

    Francillon, Wesley

    This dissertation is an investigation of materials and processed under consideration for next generation thermal structural oxides with potential applications as thermal barrier coatings; wherein, high temperature stability and mechanical properties affect durability. Two notable next generation materials systems under investigation are pyrochlore and co-doped zirconia oxides. The motivation for this work is based on current limitations of the currently used thermal barrier material of yttria stabilized zirconia (YSZ) deposited by the plasma spray processes. The rapid quenching associated with the plasma spray process, results in a metastable structure that is a non-transformable tetragonal structure in the yttria partially stabilized zirconia system rather than the equilibrium anticipated two phase mixture of cubic and monoclinic phases. It has been shown that this metastable structure offers enhanced toughness and thus durability during thermomechanical cycling from the operating temperatures in excess of 1000C to ambient. However, the metastable oxides are susceptible to partitioning at temperatures greater than 1200C, thus resulting in a transformation of the tetragonal phase oxides. Transformations of the tetragonal prime phase into the parent cubic and tetragonal prime phase result in coating degradation. Several of the emerging oxides are based on rare earth additions to zirconia. However, there is limited information of the high temperature stability of these oxide coatings and more notably these compositions exhibit limited toughness for durable performance. A potential ternary composition based on the YSZ system that offers the ability to tailor the phase structure is based YO1.5-TiO2 -ZrO2. The ternary of YO1.5-TiO2-ZrO 2 has the current TBC composition of seven molar percent yttria stabilized zirconia, pyrochlore phase oxide and zirconia doped with yttria and titania additions (Ti-YSZ). The Ti-YSZ phase field is of interest because at equilibrium it is

  18. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease.

    Science.gov (United States)

    Nalle, S C; Turner, J R

    2015-07-01

    Compromised intestinal barrier function is a prominent feature of inflammatory bowel disease (IBD). However, links between intestinal barrier loss and disease extend much further, including documented associations with celiac disease, type I diabetes, rheumatoid arthritis, and multiple sclerosis. Intestinal barrier loss has also been proposed to have a critical role in the pathogenesis of graft-versus-host disease (GVHD), a serious, potentially fatal consequence of hematopoietic stem cell transplantation. Experimental evidence has begun to support this view, as barrier loss and its role in initiating and establishing a pathogenic inflammatory cycle in GVHD is emerging. Here we discuss similarities between IBD and GVHD, mechanisms of intestinal barrier loss in these diseases, and the crosstalk between barrier loss and the immune system, with a special focus on natural killer (NK) cells. Unanswered questions and future research directions on the topic are discussed along with implications for treatment.

  19. Effect of thermal barrier coatings on the performance of steam and water-cooled gas turbine/steam turbine combined cycle system

    Science.gov (United States)

    Nainiger, J. J.

    1978-01-01

    An analytical study was made of the performance of air, steam, and water-cooled gas-turbine/steam turbine combined-cycle systems with and without thermal-barrier coatings. For steam cooling, thermal barrier coatings permit an increase in the turbine inlet temperature from 1205 C (2200 F), resulting in an efficiency improvement of 1.9 percentage points. The maximum specific power improvement with thermal barriers is 32.4 percent, when the turbine inlet temperature is increased from 1425 C (2600 F) to 1675 C (3050 F) and the airfoil temperature is kept the same. For water cooling, the maximum efficiency improvement is 2.2 percentage points at a turbine inlet temperature of 1683 C (3062 F) and the maximum specific power improvement is 36.6 percent by increasing the turbine inlet temperature from 1425 C (2600 F) to 1730 C (3150 F) and keeping the airfoil temperatures the same. These improvements are greater than that obtained with combined cycles using air cooling at a turbine inlet temperature of 1205 C (2200 F). The large temperature differences across the thermal barriers at these high temperatures, however, indicate that thermal stresses may present obstacles to the use of coatings at high turbine inlet temperatures.

  20. Fusion near and below the barrier for the systems 32,34S+24,25,26Mg and 32S+27Al

    Science.gov (United States)

    Berkowitz, G. M.; Braun-Munzinger, P.; Karp, J. S.; Freifelder, R. H.; Renner, T. R.; Wilschut, H. W.

    1983-08-01

    Excitation functions are reported for total fusion near and below the Coulomb barrier of the systems 32,34S+24,25,26Mg and 27Al. The data cannot be reproduced by one-dimensional barrier penetration calculations. The enhancement of the cross sections at low energies is compared to predictions of models taking into acount the static deformation or zero point vibration of the reaction partners. Calculations including zero point motion do not reproduce the observed variations of the measured cross sections with respect to the neutron number of target and projectile. Reasonable agreement is obtained when calculating fusion between statically deformed nuclei. Finally, the fusion process is described in a quantum mechanical coupled channels model, indicating the importance of dynamical effect on sub-barrier fusion. NUCLEAR REACTIONS 24,25,26Mg, 27Al(32,34S, Fusion) 0.9barrier parameters; discussed importance of zero point motion, static deformation, coupled channels effects on fusion process.

  1. Dielectric barrier discharges in analytical chemistry.

    Science.gov (United States)

    Meyer, C; Müller, S; Gurevich, E L; Franzke, J

    2011-06-21

    The present review reflects the importance of dielectric barrier discharges in analytical chemistry. Special about this discharge is-and in contrast to usual discharges with direct current-that the plasma is separated from one or two electrodes by a dielectric barrier. This gives rise to two main features of the dielectric barrier discharges; it can serve as dissociation and excitation device and as ionization mechanism, respectively. The article portrays the various application fields for dielectric barrier discharges in analytical chemistry, for example the use for elemental detection with optical spectrometry or as ionization source for mass spectrometry. Besides the introduction of different kinds of dielectric barrier discharges used for analytical chemistry from the literature, a clear and concise classification of dielectric barrier discharges into capacitively coupled discharges is provided followed by an overview about the characteristics of a dielectric barrier discharge concerning discharge properties and the ignition mechanism.

  2. A Theoretical Model for Predicting Residual Stress Generation in Fabrication Process of Double-Ceramic-Layer Thermal Barrier Coating System

    Science.gov (United States)

    Song, Yan; Wu, Weijie; Xie, Feng; Liu, Yilun; Wang, Tiejun

    2017-01-01

    Residual stress arisen in fabrication process of Double-Ceramic-Layer Thermal Barrier Coating System (DCL-TBCs) has a significant effect on its quality and reliability. In this work, based on the practical fabrication process of DCL-TBCs and the force and moment equilibrium, a theoretical model was proposed at first to predict residual stress generation in its fabrication process, in which the temperature dependent material properties of DCL-TBCs were incorporated. Then, a Finite Element method (FEM) has been carried out to verify our theoretical model. Afterwards, some important geometric parameters for DCL-TBCs, such as the thickness ratio of stabilized Zirconia (YSZ, ZrO2-8%Y2O3) layer to Lanthanum Zirconate (LZ, La2Zr2O7) layer, which is adjustable in a wide range in the fabrication process, have a remarkable effect on its performance, therefore, the effect of this thickness ratio on residual stress generation in the fabrication process of DCL-TBCs has been systematically studied. In addition, some thermal spray treatment, such as the pre-heating treatment, its effect on residual stress generation has also been studied in this work. It is found that, the final residual stress mainly comes from the cooling down process in the fabrication of DCL-TBCs. Increasing the pre-heating temperature can obviously decrease the magnitude of residual stresses in LZ layer, YSZ layer and substrate. With the increase of the thickness ratio of YSZ layer to LZ layer, magnitudes of residual stresses arisen in LZ layer and YSZ layer will increase while residual stress in substrate will decrease. PMID:28103275

  3. Advances in monitoring the human dimension of natural resource systems: an example from the Great Barrier Reef

    Science.gov (United States)

    Marshall, N. A.; Bohensky, E.; Curnock, M.; Goldberg, J.; Gooch, M.; Nicotra, B.; Pert, P.; Scherl, L. M.; Stone-Jovicich, S.; Tobin, R. C.

    2016-11-01

    The aim of this paper is to demonstrate the feasibility and potential utility of decision-centric social-economic monitoring using data collected from Great Barrier Reef (Reef) region. The social and economic long term monitoring program (SELTMP) for the Reef is a novel attempt to monitor the social and economic dimensions of social-ecological change in a globally and nationally important region. It represents the current status and condition of the major user groups of the Reef with the potential to simultaneously consider trends, interconnections, conflicts, dependencies and vulnerabilities. Our approach was to combine a well-established conceptual framework with a strong governance structure and partnership arrangement that enabled the co-production of knowledge. The framework is a modification of the Millennium Ecosystem Assessment and it was used to guide indicator choice. Indicators were categorised as; (i) resource use and dependency, (ii) ecosystem benefits and well-being, and (iii) drivers of change. Data were collected through secondary datasets where existing and new datasets were created where not, using standard survey techniques. Here we present an overview of baseline results of new survey data from commercial-fishers (n = 210), marine-based tourism operators (n = 119), tourists (n = 2877), local residents (n = 3181), and other Australians (n = 2002). The indicators chosen describe both social and economic components of the Reef system and represent an unprecedented insight into the ways in which people currently use and depend on the Reef, the benefits that they derive, and how they perceive, value and relate to the Reef and each other. However, the success of a program such as the SELTMP can only occur with well-translated cutting-edge data and knowledge that are collaboratively produced, adaptive, and directly feeds into current management processes. We discuss how data from the SELTMP have already been incorporated into Reef management decision

  4. A Theoretical Model for Predicting Residual Stress Generation in Fabrication Process of Double-Ceramic-Layer Thermal Barrier Coating System.

    Science.gov (United States)

    Song, Yan; Wu, Weijie; Xie, Feng; Liu, Yilun; Wang, Tiejun

    2017-01-01

    Residual stress arisen in fabrication process of Double-Ceramic-Layer Thermal Barrier Coating System (DCL-TBCs) has a significant effect on its quality and reliability. In this work, based on the practical fabrication process of DCL-TBCs and the force and moment equilibrium, a theoretical model was proposed at first to predict residual stress generation in its fabrication process, in which the temperature dependent material properties of DCL-TBCs were incorporated. Then, a Finite Element method (FEM) has been carried out to verify our theoretical model. Afterwards, some important geometric parameters for DCL-TBCs, such as the thickness ratio of stabilized Zirconia (YSZ, ZrO2-8%Y2O3) layer to Lanthanum Zirconate (LZ, La2Zr2O7) layer, which is adjustable in a wide range in the fabrication process, have a remarkable effect on its performance, therefore, the effect of this thickness ratio on residual stress generation in the fabrication process of DCL-TBCs has been systematically studied. In addition, some thermal spray treatment, such as the pre-heating treatment, its effect on residual stress generation has also been studied in this work. It is found that, the final residual stress mainly comes from the cooling down process in the fabrication of DCL-TBCs. Increasing the pre-heating temperature can obviously decrease the magnitude of residual stresses in LZ layer, YSZ layer and substrate. With the increase of the thickness ratio of YSZ layer to LZ layer, magnitudes of residual stresses arisen in LZ layer and YSZ layer will increase while residual stress in substrate will decrease.

  5. Systemic lupus erythematosus: Specific features of its course and therapy options

    Directory of Open Access Journals (Sweden)

    Aleksandr Mikhailovich Lila

    2015-01-01

    Full Text Available The prevalence of systemic lupus erythematosus (SLE varies greatly in different regions of the world. The disease is encountered in different age groups; however it is most common in young and adolescent women (its peak incidence is in the range of 15–25 years. Familial SLE cases are known. The course of SLE in pregnant women is noted to have features due to an increased risk for complications and to pharmacotherapeutic peculiarities. Risk factors for poor pregnancy outcomes, such as high disease activity at the time of conception, active lupus nephritis, and the presence of antiphospholipid antibodies (APA, are identified in patients with SLE. The paper presents antenatal fetal death predictors: proteinuria, thrombocytopenia, APA, and hypertension. When SLE is concurrent with secondary antiphospholipid syndrome (APS, the risk of poor pregnancy outcome is 30%. Management tactics for pregnant women with APS and a dosage regimen are shown to largely depend on history data (the presence (absence of nonplacental thromboses, the number of spontaneous abortions, prior therapy, etc.. There are four patient groups: 1 patients who have only anticardiolipin antibodies without previous pregnancy or one episode of unexplained abortion at less than 10 weeks’ gestation with no history of thrombosis; 2 those who have APS with no history of nonplacental thrombosis and have anticardiolipin antibodies and a history of two or more unexplained spontaneous abortions at less than 10 weeks’ gestation; 3 those who have APS and a history of nonplacental thromboses (who have taken warfarin prior to pregnancy; 4 those in whom standard therapy is ineffective during their next pregnancy. The paper presents therapy options for each patient group.It is concluded that effective therapeutic strategy for SLE, including that in pregnant women, implies patient monitoring to long maintain remission (low disease activity.

  6. Prevalence, severity, and clinical features of acute and chronic pancreatitis in patients with systemic lupus erythematosus.

    Science.gov (United States)

    Wang, Qiang; Shen, Min; Leng, Xiaomei; Zeng, Xiaofeng; Zhang, Fengchun; Qian, Jiaming

    2016-10-01

    Pancreatitis is a rare, life-threatening complication of systemic lupus erythematosus (SLE). This study aimed to describe the clinical features of acute pancreatitis (AP) and chronic pancreatitis (CP) in patients with SLE. Data of patients who fulfilled the revised criteria of the American Rheumatism Association for diagnosis of SLE were retrospectively analyzed. SLE activity was graded according to the SLE Disease Activity Index. Logistic regression analysis was conducted to find out independent associations. Survival rates were estimated by using Kaplan-Meier plots. This study included 5665 SLE patients admitted between January 1983 and January 2014, of whom 52 patients were diagnosed with pancreatitis. Pancreatitis prevalence in SLE patients was 0.92 % (52/5665). AP (0.8 %, 46/5665) was more prevalent than CP (0.1 %, 6/5665), presented mostly during active SLE, and affected more organs. Hypertriglyceridemia occurred in 76.9 % of AP patients and in none of the CP patients. AP patients were divided into severe (n = 10) or mild (n = 20) cases. The average triglyceride level in severe AP cases was higher than that in mild AP cases (P = 0.006), and the mortality rate of lupus-associated AP was 32.6 % (15/46). Concomitant infections and thrombocytopenia were independently associated with poor prognosis (P < 0.001, P = 0.028, respectively). There were significant differences in the clinical manifestations of AP and CP. Patients with severe AP were found to have a higher incidence of concomitant infection and serum triglyceride levels. Concomitant infections and thrombocytopenia were independent risk factors for poor prognosis.

  7. Clinical features of organophosphate poisoning: A review of different classification systems and approaches

    Directory of Open Access Journals (Sweden)

    John Victor Peter

    2014-01-01

    Full Text Available Purpose: The typical toxidrome in organophosphate (OP poisoning comprises of the Salivation, Lacrimation, Urination, Defecation, Gastric cramps, Emesis (SLUDGE symptoms. However, several other manifestations are described. We review the spectrum of symptoms and signs in OP poisoning as well as the different approaches to clinical features in these patients. Materials and Methods: Articles were obtained by electronic search of PubMed® between 1966 and April 2014 using the search terms organophosphorus compounds or phosphoric acid esters AND poison or poisoning AND manifestations. Results: Of the 5026 articles on OP poisoning, 2584 articles pertained to human poisoning; 452 articles focusing on clinical manifestations in human OP poisoning were retrieved for detailed evaluation. In addition to the traditional approach of symptoms and signs of OP poisoning as peripheral (muscarinic, nicotinic and central nervous system receptor stimulation, symptoms were alternatively approached using a time-based classification. In this, symptom onset was categorized as acute (within 24-h, delayed (24-h to 2-week or late (beyond 2-week. Although most symptoms occur with minutes or hours following acute exposure, delayed onset symptoms occurring after a period of minimal or mild symptoms, may impact treatment and timing of the discharge following acute exposure. Symptoms and signs were also viewed as an organ specific as cardiovascular, respiratory or neurological manifestations. An organ specific approach enables focused management of individual organ dysfunction that may vary with different OP compounds. Conclusions: Different approaches to the symptoms and signs in OP poisoning may better our understanding of the underlying mechanism that in turn may assist with the management of acutely poisoned patients.

  8. A-Survey of Feature Extraction and Classification Techniques in OCR Systems

    Directory of Open Access Journals (Sweden)

    Rohit Verma

    2012-11-01

    Full Text Available This paper describes a set of feature extraction and classification techniques, which play very important role in the recognition of characters. Feature extraction provides us methods with the help of which we can identify characters uniquely and with high degree of accuracy. Feature extraction helps us to find the shape contained in the pattern. Although a number of techniques are available for feature extraction and classification, but the choice of an excellent technique decides the degree of accuracy of recognition. A lot of research has been done in this field and new techniques of extraction and classification has been developed. The objective of this paper is to review these techniques, so that the set of these techniques can be appreciated.

  9. FX barriers with smile dynamics

    NARCIS (Netherlands)

    Baker, Glyn; Beneder, Reimer; Zilber, Alex

    2004-01-01

    Our mandate in this work has been to isolate the features of smile consistent models that are most relevant to the pricing of barrier options. We consider the two classical approaches of stochastic and (parametric) local volatility. Although neither has been particularly successful in practice their

  10. Artificial immune system based on adaptive clonal selection for feature selection and parameters optimisation of support vector machines

    Science.gov (United States)

    Sadat Hashemipour, Maryam; Soleimani, Seyed Ali

    2016-01-01

    Artificial immune system (AIS) algorithm based on clonal selection method can be defined as a soft computing method inspired by theoretical immune system in order to solve science and engineering problems. Support vector machine (SVM) is a popular pattern classification method with many diverse applications. Kernel parameter setting in the SVM training procedure along with the feature selection significantly impacts on the classification accuracy rate. In this study, AIS based on Adaptive Clonal Selection (AISACS) algorithm has been used to optimise the SVM parameters and feature subset selection without degrading the SVM classification accuracy. Several public datasets of University of California Irvine machine learning (UCI) repository are employed to calculate the classification accuracy rate in order to evaluate the AISACS approach then it was compared with grid search algorithm and Genetic Algorithm (GA) approach. The experimental results show that the feature reduction rate and running time of the AISACS approach are better than the GA approach.

  11. Data-driven technology for engineering systems health management design approach, feature construction, fault diagnosis, prognosis, fusion and decisions

    CERN Document Server

    Niu, Gang

    2017-01-01

    This book introduces condition-based maintenance (CBM)/data-driven prognostics and health management (PHM) in detail, first explaining the PHM design approach from a systems engineering perspective, then summarizing and elaborating on the data-driven methodology for feature construction, as well as feature-based fault diagnosis and prognosis. The book includes a wealth of illustrations and tables to help explain the algorithms, as well as practical examples showing how to use this tool to solve situations for which analytic solutions are poorly suited. It equips readers to apply the concepts discussed in order to analyze and solve a variety of problems in PHM system design, feature construction, fault diagnosis and prognosis.

  12. An intelligent recovery progress evaluation system for ACL reconstructed subjects using integrated 3-D kinematics and EMG features.

    Science.gov (United States)

    Malik, Owais A; Senanayake, S M N Arosha; Zaheer, Dansih

    2015-03-01

    An intelligent recovery evaluation system is presented for objective assessment and performance monitoring of anterior cruciate ligament reconstructed (ACL-R) subjects. The system acquires 3-D kinematics of tibiofemoral joint and electromyography (EMG) data from surrounding muscles during various ambulatory and balance testing activities through wireless body-mounted inertial and EMG sensors, respectively. An integrated feature set is generated based on different features extracted from data collected for each activity. The fuzzy clustering and adaptive neuro-fuzzy inference techniques are applied to these integrated feature sets in order to provide different recovery progress assessment indicators (e.g., current stage of recovery, percentage of recovery progress as compared to healthy group, etc.) for ACL-R subjects. The system was trained and tested on data collected from a group of healthy and ACL-R subjects. For recovery stage identification, the average testing accuracy of the system was found above 95% (95-99%) for ambulatory activities and above 80% (80-84%) for balance testing activities. The overall recovery evaluation performed by the proposed system was found consistent with the assessment made by the physiotherapists using standard subjective/objective scores. The validated system can potentially be used as a decision supporting tool by physiatrists, physiotherapists, and clinicians for quantitative rehabilitation analysis of ACL-R subjects in conjunction with the existing recovery monitoring systems.

  13. Expression of Astrocytic Type 2 Angiotensin Receptor in Central Nervous System Inflammation Correlates With Blood-Brain Barrier Breakdown

    DEFF Research Database (Denmark)

    Füchtbauer, Laila; Toft-Hansen, Henrik; Khorooshi, Reza;

    2010-01-01

    is involved during BBB breakdown. We studied the type 2 angiotensin receptor AT(2) because of its suggested neuroprotective role. Two models of brain inflammation were used to distinguish solute versus cellular barrier functions. Both leukocytes and horseradish peroxidase (HRP) accumulated in the perivascular...

  14. Spectral feature with sub-natural linewidth due to quantum interference in a four-level system

    Institute of Scientific and Technical Information of China (English)

    Yang Li-Jun; Zhang Lian-Shui; Zhuang Zhong-Hong; Guo Qing-Lin; Fu Guang-Sheng

    2008-01-01

    This paper studies the narrow spectral feature appearing in a four-level system coupled by two strong coherent fields and probed by a weak laser field. The linewidth is examined as a function of the Rabi frequencies of coupling fields, and the result is explained by using the dressed-state formalism.

  15. 77 FR 38611 - Privacy Act of 1974; System of Records-Study of Promising Features of Teacher Preparation Programs

    Science.gov (United States)

    2012-06-28

    ... Teacher Preparation Programs'' (18-13-29). The National Center for Education Evaluation and Regional... Privacy Act of 1974; System of Records--Study of Promising Features of Teacher Preparation Programs AGENCY... Abt Associates to conduct a rigorous study of the effect on student learning of teachers who...

  16. Genomic Targets and Features of BarA-UvrY (-SirA Signal Transduction Systems.

    Directory of Open Access Journals (Sweden)

    Tesfalem R Zere

    Full Text Available The two-component signal transduction system BarA-UvrY of Escherichia coli and its orthologs globally regulate metabolism, motility, biofilm formation, stress resistance, virulence of pathogens and quorum sensing by activating the transcription of genes for regulatory sRNAs, e.g. CsrB and CsrC in E. coli. These sRNAs act by sequestering the RNA binding protein CsrA (RsmA away from lower affinity mRNA targets. In this study, we used ChIP-exo to identify, at single nucleotide resolution, genomic sites for UvrY (SirA binding in E. coli and Salmonella enterica. The csrB and csrC genes were the strongest targets of crosslinking, which required UvrY phosphorylation by the BarA sensor kinase. Crosslinking occurred at two sites, an inverted repeat sequence far upstream of the promoter and a site near the -35 sequence. DNAse I footprinting revealed specific binding of UvrY in vitro only to the upstream site, indicative of additional binding requirements and/or indirect binding to the downstream site. Additional genes, including cspA, encoding the cold-shock RNA-binding protein CspA, showed weaker crosslinking and modest or negligible regulation by UvrY. We conclude that the global effects of UvrY/SirA on gene expression are primarily mediated by activating csrB and csrC transcription. We also used in vivo crosslinking and other experimental approaches to reveal new features of csrB/csrC regulation by the DeaD and SrmB RNA helicases, IHF, ppGpp and DksA. Finally, the phylogenetic distribution of BarA-UvrY was analyzed and found to be uniquely characteristic of γ-Proteobacteria and strongly anti-correlated with fliW, which encodes a protein that binds to CsrA and antagonizes its activity in Bacillus subtilis. We propose that BarA-UvrY and orthologous TCS transcribe sRNA antagonists of CsrA throughout the γ-Proteobacteria, but rarely or never perform this function in other species.

  17. Genomic Targets and Features of BarA-UvrY (-SirA) Signal Transduction Systems.

    Science.gov (United States)

    Zere, Tesfalem R; Vakulskas, Christopher A; Leng, Yuanyuan; Pannuri, Archana; Potts, Anastasia H; Dias, Raquel; Tang, Dongjie; Kolaczkowski, Bryan; Georgellis, Dimitris; Ahmer, Brian M M; Romeo, Tony

    2015-01-01

    The two-component signal transduction system BarA-UvrY of Escherichia coli and its orthologs globally regulate metabolism, motility, biofilm formation, stress resistance, virulence of pathogens and quorum sensing by activating the transcription of genes for regulatory sRNAs, e.g. CsrB and CsrC in E. coli. These sRNAs act by sequestering the RNA binding protein CsrA (RsmA) away from lower affinity mRNA targets. In this study, we used ChIP-exo to identify, at single nucleotide resolution, genomic sites for UvrY (SirA) binding in E. coli and Salmonella enterica. The csrB and csrC genes were the strongest targets of crosslinking, which required UvrY phosphorylation by the BarA sensor kinase. Crosslinking occurred at two sites, an inverted repeat sequence far upstream of the promoter and a site near the -35 sequence. DNAse I footprinting revealed specific binding of UvrY in vitro only to the upstream site, indicative of additional binding requirements and/or indirect binding to the downstream site. Additional genes, including cspA, encoding the cold-shock RNA-binding protein CspA, showed weaker crosslinking and modest or negligible regulation by UvrY. We conclude that the global effects of UvrY/SirA on gene expression are primarily mediated by activating csrB and csrC transcription. We also used in vivo crosslinking and other experimental approaches to reveal new features of csrB/csrC regulation by the DeaD and SrmB RNA helicases, IHF, ppGpp and DksA. Finally, the phylogenetic distribution of BarA-UvrY was analyzed and found to be uniquely characteristic of γ-Proteobacteria and strongly anti-correlated with fliW, which encodes a protein that binds to CsrA and antagonizes its activity in Bacillus subtilis. We propose that BarA-UvrY and orthologous TCS transcribe sRNA antagonists of CsrA throughout the γ-Proteobacteria, but rarely or never perform this function in other species.

  18. Approaches to formalization of the informal waste sector into municipal solid waste management systems in low- and middle-income countries: Review of barriers and success factors

    DEFF Research Database (Denmark)

    Aparcana Robles, Sandra Roxana

    2016-01-01

    , this paper aims to address this gap by explaining to policy- and decision-makers, and to waste managers in the private sector, certain dynamics that can be observed and that should be taken into account when designing formalization strategies that are adapted to their particular socioeconomic and political......The Municipal Solid Waste Management (MSWM) sector represents a major challenge for low-and middle-income countries due to significant environmental and socioeconomic issues involving rapid urbanization, their MSWM systems, and the existence of the informal waste sector. Recognizing its role...... on the assessment, the paper discussed possible links between formalization approaches and barriers, the 'persistent' challenges that represent barriers to formalization, as well as key enabling factors improving the likelihood of successful formalization. Regardless of the type of approach adopted to formalization...

  19. Altered permeability barrier structure in cholesteatoma matrix

    DEFF Research Database (Denmark)

    Svane-Knudsen, Viggo; Halkier-Sørensen, Lars; Rasmussen, Gurli

    2002-01-01

    The stratum corneum of the cholesteatoma epithelium comprises the greater part of the cholesteatoma matrix. The permeability barrier that militates against diffusion and penetration of infectious and toxic agents into and through the epithelium is situated here. The multiple long sheets of lamellar...... lipid structures filling the intercellular spaces mainly control the barrier function. The barrier in cholesteatoma epithelium is several times thicker than in unaffected skin but presents distinctive features of a defective barrier as seen in other scaling skin diseases. The intercellular spaces appear...

  20. CargoCBM - Feature Generation and Classification for a Condition Monitoring System for Freight Wagons

    Science.gov (United States)

    Gericke, C.; Hecht, M.

    2012-05-01

    Despite the fact that rail freight transport is one of the most environmentally friendly matters of transport, its growth has been far behind the growth of freight transport in general. Studies showed that a competitive disadvantage is caused by a low availability of rolling stock, especially freight wagons. Changing from a time based to a condition based maintenance strategy is believed to decrease down times by at least one third. To make condition based maintenance for freight wagons possible the TU Berlin and five industry partners started the research project CargoCBM. One task in this project is to develop algorithms for the automatic on-board diagnosis of wheel flats. The focus of the work is on the process of feature generation and feature selection as well as the application of different classifiers to automatically evaluate the data. Based on the results of measured data, features were selected and tested with different classifiers. Thought advanced classifiers such as neural networks have been analysed in accordance to their classification accuracy. It can be shown that with carefully constructed and selected features comparatively simple classifiers can lead to excellent results.