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Sample records for baby hamster kidney

  1. Comparative susceptibility of vero and baby hamster kidney cell ...

    African Journals Online (AJOL)

    Comparative susceptibility of vero and baby hamster kidney cell lines to PPR virus. ... Bulletin of Animal Health and Production in Africa ... The inoculated BHK and Vero cells supported the growth of the virus with syncytia formation more commonly observed in the BHK cells while vacuolation and cell disintegration were ...

  2. Photodynamic inactivation of rubella virus enhances recombination with a latent virus of a baby hamster kidney cell line BHK21

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Nobuto; Urade, Masahiro (Hahnemann Univ. School of Medicine, Philadelphia, PA (USA))

    1989-09-01

    Rubella virus is very sensitive to photodynamic action. When tested with 1.2 x 10{sup -5} M toluidine blue and 8 W fluorescent lamp at a fluence of 11 W/m{sup 2}, inactivation kinetics showed a linear single hit curve with a k value of 1.48 min{sup -1}. Photodynamic inactivation of rubella virus greatly enhanced recombination with a latent virus (R-virus) of baby hamster kidney BHK21 cells. In contrast, no hybrids were detected in lysates of the cells infected with either UV-treated or untreated rubella virus. Therefore, hybrid viruses were readily detected only in lysates of BHK21 cells infected with photodynamically treated rubella virus. Photodynamic damage of rubella virus genomes generated a new hybrid type (hybrid type 3) in addition to a previously described type 2 hybrid (formerly designated as HPV-RV variant). Although both of these hybrid types carry the CF antigens of rubella virus, plaque forming ability of type 3 hybrid is neutralized neither by anti-rubella serum nor by anti-latent virus serum while type 2 hybrid is neutralized by anti-latent virus serum. (author).

  3. Photodynamic inactivation of rubella virus enhances recombination with a latent virus of a baby hamster kidney cell line BHK21

    International Nuclear Information System (INIS)

    Yamamoto, Nobuto; Urade, Masahiro

    1989-01-01

    Rubella virus is very sensitive to photodynamic action. When tested with 1.2 x 10 -5 M toluidine blue and 8 W fluorescent lamp at a fluence of 11 W/m 2 , inactivation kinetics showed a linear single hit curve with a k value of 1.48 min -1 . Photodynamic inactivation of rubella virus greatly enhanced recombination with a latent virus (R-virus) of baby hamster kidney BHK21 cells. In contrast, no hybrids were detected in lysates of the cells infected with either UV-treated or untreated rubella virus. Therefore, hybrid viruses were readily detected only in lysates of BHK21 cells infected with photodynamically treated rubella virus. Photodynamic damage of rubella virus genomes generated a new hybrid type (hybrid type 3) in addition to a previously described type 2 hybrid (formerly designated as HPV-RV variant). Although both of these hybrid types carry the CF antigens of rubella virus, plaque forming ability of type 3 hybrid is neutralized neither by anti-rubella serum nor by anti-latent virus serum while type 2 hybrid is neutralized by anti-latent virus serum. (author)

  4. Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells

    Energy Technology Data Exchange (ETDEWEB)

    Fendrick, J.L.; Iglewski, W.J. (Univ. of Rochester, NY (USA))

    1989-01-01

    Polyoma virus-transformed baby hamster kidney (pyBHK) cells were cultured in medium containing ({sup 32}P)orthophosphate and 105 (vol/vol) fetal bovine serum. A {sup 32}P-labeled protein with an apparent molecular mass of 97 kDa was immunoprecipitated from cell lysates with antiserum to ADP-ribosylated elongation factor 2 (EF-2). The {sup 32}P labeling of the protein was enhanced by culturing cells in medium containing 2% serum instead of 10% serum. The {sup 32}P label was completely removed from the protein by treatment with snake venom phosphodiesterase and the digestion product was identified as ({sup 32}P)AMP, indicating the protein was mono-ADP-ribosylated. HPLC analysis of tryptic peptides of the {sup 32}P-labeled 97-kDa protein and purified EF-2, which was ADP-ribosylated in vitro with diphtheria toxin fragment A and ({sup 32}P)NAD, demonstrated an identical labeled peptide in the two proteins. The data strongly suggest that EF-2 was endogenously ADP-ribosylated in pyBHK cells. Maximum incorporation of radioactivity in EF-2 occurred by 12 hr and remained constant over the subsequent 12 hr. It was estimated that 30-35% of the EF-2 was ADP-ribosylated in cells cultured in medium containing 2% serum. When {sup 32}P-labeled cultures were incubated in medium containing unlabeled phosphate, the {sup 32}P label was lost from the EF-2 within 30 min.

  5. Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells

    International Nuclear Information System (INIS)

    Fendrick, J.L.; Iglewski, W.J.

    1989-01-01

    Polyoma virus-transformed baby hamster kidney (pyBHK) cells were cultured in medium containing [ 32 P]orthophosphate and 105 (vol/vol) fetal bovine serum. A 32 P-labeled protein with an apparent molecular mass of 97 kDa was immunoprecipitated from cell lysates with antiserum to ADP-ribosylated elongation factor 2 (EF-2). The 32 P labeling of the protein was enhanced by culturing cells in medium containing 2% serum instead of 10% serum. The 32 P label was completely removed from the protein by treatment with snake venom phosphodiesterase and the digestion product was identified as [ 32 P]AMP, indicating the protein was mono-ADP-ribosylated. HPLC analysis of tryptic peptides of the 32 P-labeled 97-kDa protein and purified EF-2, which was ADP-ribosylated in vitro with diphtheria toxin fragment A and [ 32 P]NAD, demonstrated an identical labeled peptide in the two proteins. The data strongly suggest that EF-2 was endogenously ADP-ribosylated in pyBHK cells. Maximum incorporation of radioactivity in EF-2 occurred by 12 hr and remained constant over the subsequent 12 hr. It was estimated that 30-35% of the EF-2 was ADP-ribosylated in cells cultured in medium containing 2% serum. When 32 P-labeled cultures were incubated in medium containing unlabeled phosphate, the 32 P label was lost from the EF-2 within 30 min

  6. Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1.

    Science.gov (United States)

    Hauff, Kristin D; Mitchell, Ryan W; Xu, Fred Y; Dembinski, Thomas; Mymin, David; Zha, Xiaohui; Choy, Patrick C; Hatch, Grant M

    2011-09-01

    ATP binding cassette A1 (ABCA1) transports cholesterol, phospholipids and lipophilic molecules to and across cellular membranes. We examined if ABCA1 expression altered cellular de novo glycerolipid biosynthesis in growing Baby hamster kidney (BHK) cells. Mock BHK cells or cells expressing a mifepristone-inducible ABCA1 (ABCA1) were incubated plus or minus mifepristone and then with [(3)H]serine or [(3)H]inositol or [(3)H]ethanolamine or [methyl-(3)H]choline or [(3)H]glycerol or [(14)C]oleate and radioactivity incorporated into glycerolipids determined. Mifepristone did not affect [1,3-(3)H]glycerol or [(14)C]oleate or [(3)H]ethanolamine or [methyl-(3)H]choline uptake in BHK cells. In contrast, [(3)H]glycerol and [(14)C]oleate incorporated into phosphatidylserine (PtdSer) were elevated 2.4-fold (p < 0.05) and 54% (p < 0.05), respectively, upon ABCA1 induction confirming increased PtdSer biosynthesis from these precursors. However, mifepristone inhibited [(3)H]serine uptake and incorporation into PtdSer indicating that PtdSer synthesis from serine in BHK cells is dependent on serine uptake. Mifepristone stimulated [(3)H]inositol uptake in mock and ABCA1 cells but not its incorporation into phosphatidylinositol indicating that its synthesis from inositol is independent of inositol uptake in BHK cells. [(3)H]glycerol and [(14)C]oleate incorporated into triacylglycerol were reduced and into diacylglycerol elevated only in mifepristone-induced ABCA1 expressing cells due to a decrease in diacylglycerol acyltransferase-1 (DGAT-1) activity. The presence of trichostatin A, a class I and II histone deacetylase inhibitor, reversed the ABCA1-mediated reduction in DGAT-1 activity but did not affect DGAT-1 mRNA expression. Thus, mifepristone has diverse effects on de novo glycerolipid synthesis. We suggest that caution should be exercised when using mifepristone-inducible systems for studies of glycerolipid metabolism in cells expressing glucocorticoid responsive receptors.

  7. Somatic mutations in stilbene estrogen-induced Syrian hamster kidney tumors identified by DNA fingerprinting

    Directory of Open Access Journals (Sweden)

    Roy Deodutta

    2004-01-01

    Full Text Available Abstract Kidney tumors from stilbene estrogen (diethylstilbestrol-treated Syrian hamsters were screened for somatic genetic alterations by Random Amplified Polymorphic DNA-polymerase chain-reaction (RAPD-PCR fingerprinting. Fingerprints from tumor tissue were generated by single arbitrary primers and compared with fingerprints for normal tissue from the same animal, as well as normal and tumor tissues from different animals. Sixty one of the arbitrary primers amplified 365 loci that contain approximately 476 kbp of the hamster genome. Among these amplified DNA fragments, 44 loci exhibited either qualitative or quantitative differences between the tumor tissues and normal kidney tissues. RAPD-PCR loci showing decreased and increased intensities in tumor tissue DNA relative to control DNA indicate that loci have undergone allelic losses and gains, respectively, in the stilbene estrogen-induced tumor cell genome. The presence or absence of the amplified DNA fragments indicate homozygous insertions or deletions in the kidney tumor DNA compared to the age-matched normal kidney tissue DNA. Seven of 44 mutated loci also were present in the kidney tissues adjacent to tumors (free of macroscopic tumors. The presence of mutated loci in uninvolved (non-tumor surrounding tissue adjacent to tumors from stilbene estrogen-treated hamsters suggests that these mutations occurred in the early stages of carcinogenesis. The cloning and sequencing of RAPD amplified loci revealed that one mutated locus had significant sequence similarity with the hamster Cyp1A1 gene. The results show the ability of RAPD-PCR to detect and isolate, in a single step, DNA sequences representing genetic alterations in stilbene estrogen-induced cancer cells, including losses of heterozygosity, and homozygous deletion and insertion mutations. RAPD-PCR provides an alternative molecular approach for studying cancer cytogenetics in stilbene estrogen-induced tumors in humans and experimental

  8. Autoradiographic studies of the kidneys of hamsters bearing longterm oestrogen implants

    International Nuclear Information System (INIS)

    Pantic, V.; Li, J.; Villee, C.

    1974-01-01

    The ability of kidney cells to incorporate tritiated oestradiol, thymidine or uridine was investigated in hamsters with oestrogen implants for more than six months and in corresponding control hamsters without implants. Using autoradiography the following results were obtained: The cells of some proportion of the proximal convoluted tubules showed an increased ability to incorporate tritiated oestradiol, thymidine and uridine. Many of these cells were able to transport the labeled oestrogen-receptor complex into the nuclei within 45 minutes after the administration of labeled oestradiol. The cells of the distal convoluted tubules were labeled but generally to a much smaller extent. Only some individual cells showed a tendency for an increased accumulation of oestradiol. The cytoplasm of cells in the loop of Henle seems to be covered uniformly with silver grains in both control and oestrogen treated hamsters. The cells of collecting and papillary duct tubules located in the medullary rays do not show any tendency for an increased uptake of labeled oestradiol. (orig.) [de

  9. Studies of baby hamster kidney natural cell aggregation in suspended batch cultures.

    Science.gov (United States)

    Moreira, J L; Alves, P M; Rodrigues, J M; Cruz, P E; Aunins, J G; Carrondo, M J

    1994-11-30

    Microcarrier cultures of animal cells of industrial relevance are known to shed aggregates into the suspension phase. For a BHK cell line, which is known to be prone to aggregate naturally, microcarrier and aggregate forms of culture are compared in spinner culture. In microcarrier cultures, it is shown that increasing initial microcarrier concentration yields decreasing concentration of smaller aggregates in suspension; roughly equivalent concentrations of total cells and single cells in suspension are obtained. In the absence of Cytodex 3, aggregate final size is hydrodynamically controlled in batch and semicontinuous suspension culture. Rate of agitation is the main variable controlling aggregate size in batch cultures. The range of agitation rates studied (20 to 70 rpm in 250 mL spinner flasks) produced aggregates with maximum sizes of 200 microns. Necrotic centers were not observed; this was confirmed by Trypan blue viability measurements after mechanical dissociation of aggregates and also by the constant productivity obtained from different aggregate sizes. Comparing aggregate and microcarrier culture conditions, it is shown that at 100 rpm maximum total cell concentration is larger in the absence of microcarriers; dead cell concentrations, most of which exist in suspension, are slightly larger in microcarrier culture. Total viable cell concentrations in aggregate, hydrodynamically controlled culture, are almost one order of magnitude higher than in microcarrier cultures. These results suggest that there might be advantages in using aggregate cultures under hydrodynamic control of aggregate size in lieu of microcarrier cultures for naturally aggregating cell lines.

  10. KULTUR SEL BABY HAMSTER KIDNEY (BHK MENGGUNAKAN MEDIA DULBECCO’S MODIFIED EAGLE MEDIUM (DMEM

    Directory of Open Access Journals (Sweden)

    Mashita Andiana

    2018-01-01

    Full Text Available Kultur sel merupakan suatu proses saat sel hidup ditempatkan ke dalam suatu media yang dapat membuat sel tersebut berkembang biak atau tumbuh secara in vitro, Kultur sel dapat berupa kultur sel primer maupun cell line, Metode dalam kultur sel terdiri atas kultur monolayer dan kultur suspensi. Pembuatan media kultur untuk pertumbuhan sel diusahakan memenuhi kriteria. Konstituen dasar dari media kultur yang paling banyak digunakan adalah BSS (Balanced Sald Solution. Untuk mendapatkan pertumbuhan sel yang optimal, media kultur ditambahkan serum. Serum yang biasa digunakan dalam kultur adalah serum anak sapi (calf serum, serum fetus sapi (foetal bovine serum, serum kuda dan serum manusia. Perhitungan sel menggunakan counting chamber. Metode yang digunakan adalah revival kemudian split sel, stor sel dan menghitung sel. Hasil revival  jumlah sel tertinggi didapat dari botol nomer 3 dengan jumlah sel 310 yaitu botol dengan sel BHK label tahun 2016, dan hasil split sel yang paling tinggi juga didapat dari botol kultur nomer 3 dengan jumlah sel 345 dan 311.

  11. Identification of a single chromosome in the normal human genome essential for suppression of hamster cell transformation.

    OpenAIRE

    Stoler, A; Bouck, N

    1985-01-01

    Normal human fibroblasts were fused to carcinogen-transformed baby hamster kidney (BHK) cells and found to be able to suppress the anchorage-independent transformed phenotype of the hamster cells. This suppression was not due to interspecies incompatibility, for transformation could be effectively expressed in hybrids if either the human or the BHK parent had initially been transformed by a dominantly acting viral genome. Upon growth of suppressed hybrids, loss of human chromosomes was accomp...

  12. Comparison of primary skunk brain and kidney and raccoon kidney cells with established cell lines for isolation and propagation of street rabies virus.

    OpenAIRE

    Umoh, J U; Blenden, D C

    1983-01-01

    Cell cultures prepared from skunk kidney, raccoon kidney, and skunk brain were compared with CER, murine neuroblastoma (C1300, clone NA), baby hamster kidney (BHK-21, S-13), and dog kidney (MDCK) cell lines for virus isolation and propagation of street and fixed rabies virus. The skunk brain cells were suitable for efficient replication of all the virus isolates. They were comparable to CER and murine neuroblastoma cells for virus isolation and propagation. None of the other cell cultures was...

  13. Acetylation of spermidine and methylglyoxal bis(guanylhydrazone) in baby-hamster kidney cells (BHK-21/C13).

    Science.gov (United States)

    Wallace, H M; Nuttall, M E; Robinson, F C

    1988-01-01

    Treatment of BHK-21/C13 cells with methylglyoxal bis(guanylhydrazone) (MGBG) induced the cytosolic form of spermidine N1-acetyltransferase. It stabilized the enzyme against proteolytic degradation, but the drug did not affect the enzyme activity in vitro. MGBG was itself acetylated by BHK-21/C13 cells, but at only one-tenth the rate at which spermidine was acetylated. Acetylation occurred almost exclusively in the nuclear fraction. The product was identified as N-acetyl-MGBG by h.p.l.c., by using [3H]acetyl-CoA and [14C]MGBG as co-substrates. The results suggest that the acetylation of MGBG by BHK-21/C13 cells occurs by a different acetyltransferase enzyme from that which acetylates spermidine. PMID:3421945

  14. Pregnancy and Kidney Disease

    Science.gov (United States)

    ... Donate A to Z Health Guide Pregnancy and Kidney Disease Tweet Share Print Email A new baby is ... disease and pregnancy. Can a woman with "mild" kidney disease have a baby? That depends. There is good ...

  15. Site of resistance to Necator americanus in hamsters.

    Science.gov (United States)

    Rajasekariah, G R; Deb, B N; Dhage, K R; Bose, S

    1985-12-01

    Resistance to the development of human hookworm, Necator americanus was examined in 3- to 6-week-old young adult hamsters. Only 3% of N. americanus infective third stage larvae (NaL3) reached maturity in the intestines of young adults as opposed to as many as 60% in 2-day-old baby hamsters. This seemingly effective resistance prevailing in young adults was investigated in some detail. The skin, the first site of contact for the invading NaL3, was bypassed during the infection process. Completely in vitro exsheathed NaL3 (ExNaL3) were used, and young adult hamsters were infected parenterally, by-passing the skin. Even after exsheathing the larvae artificially before infection and by-passing the skin, no improvement was seen in the development of N. americanus in the intestines of young adults. Higher infection doses also did not increase the worm burden. Some of the factors limiting the development of parasites in young adults were examined. N. americanus were monitored in lungs and intestines during various intervals after infection. Similar parasite burdens were apparent in lungs of baby as well as young adult hamsters. In the intestines, a significantly lower burden of N. americanus was seen during various intervals in young adults compared to the baby hamsters. Moreover, N. americanus were expelled soon after reaching the intestine. This comparative monitoring revealed the intestine as the seat of resistance against the establishment of N. americanus in young adult hamsters.

  16. Collodion baby

    Directory of Open Access Journals (Sweden)

    Dhaded S

    1992-01-01

    Full Text Available Collodion baby is a rare congenital disorder characterized by parchment like taught membrane covering the whole body. Other findings in our case include ectropion, eversion of lips, and flattening of nose and ears. Skin biopsy showed features consistant with the diagnosis of collodion baby. The child was treated with supportive measures like antibiotics, intravenous fluids, humidification, and application of emollients.

  17. Baby Factory

    African Journals Online (AJOL)

    Prof

    2018-01-24

    Jan 24, 2018 ... severe exploitation, such as forced labour, slavery, debt bondage, prostitution, pornography or the unlawful removal of organs”. Kalu (2011) in his report on the issue of 'baby factory' in the South East of Nigeria, described 'baby factory' as a form of child trafficking since the girls are harboured against their ...

  18. Feeding Your Baby

    Medline Plus

    Full Text Available ... pump Baby Feeding your baby Other Baby topics ') document.write(' Caring for your baby ') document.write('') } ') document.write(' Feeding your baby ') document.write('') } ') ...

  19. Feeding Your Baby

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    Full Text Available ... for your baby Feeding your baby Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ... for your baby Feeding your baby Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ...

  20. Feeding Your Baby

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    Full Text Available ... your baby Feeding your baby Common illnesses Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ... your baby Feeding your baby Common illnesses Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ...

  1. Feeding Your Baby

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    Full Text Available ... baby Feeding your baby Common illnesses Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ... baby Feeding your baby Common illnesses Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth ...

  2. Baby hatch

    OpenAIRE

    Thomsen, Diana; Burova, Tina; Bengtsson, Teresa

    2016-01-01

    The Baby Hatch is an alternative adoption process. We have re-conceptualized an already existing concept for it to fit into Danish regulations. Additionally, we have created tangible communication materials in the form of a poster and brochure that will help us to communicate the concept in a focus group discussion setup. In this project, we will be analyzing the participants’ reception of the product campaign and an awareness campaign by using a theory that is introduced by Kim Schrøder, nam...

  3. Feeding Your Baby

    Medline Plus

    Full Text Available ... Frequently asked questions Email sign up Join our online community Home > Baby > Feeding your baby Feeding your baby E-mail to a friend Please fill in all fields. Please enter a ...

  4. Feeding Your Baby

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    Full Text Available ... the health of all moms and babies. SIGN UP MARCH WITH US We're leading the fight ... the health of all moms and babies. SIGN UP [Skip to Content] March For Babies | Nacersano | Share ...

  5. Feeding Your Baby

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  6. Once Baby Arrives

    Science.gov (United States)

    ... if necessary, and prescribe the best treatment. Handling Baby's Food Safely... Protect your baby and young children by ... the safety button on the lid of commercial baby-food jars is down. If the jar lid doesn' ...

  7. Feeding Your Baby

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    Full Text Available ... baby during the first year of life. Learn how to breastfeed and why breast milk is so ... you’re feeding your baby formula , find out how to choose the best one for your baby ...

  8. Feeding Your Baby

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    Full Text Available ... Frequently asked questions Email sign up Join our online community March for Babies Nacersano Share Your Story ... Frequently asked questions Email sign up Join our online community Home > Baby > Feeding your baby Feeding your ...

  9. Feeding Your Baby

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    Full Text Available ... Home > Baby > Feeding your baby Feeding your baby E-mail to a friend Please fill in all fields. Please enter a valid e-mail address. Your information: Your recipient's information: Your ...

  10. Organic Baby Food: Better for Baby?

    Science.gov (United States)

    Healthy Lifestyle Infant and toddler health Is organic baby food better for my baby? Answers from Jay L. Hoecker, M.D. Organic foods are grown or processed without synthetic fertilizers or pesticides. Feeding ...

  11. Necator americanus and Ancylostoma ceylanicum: development of protocols for dual infection in hamsters.

    Science.gov (United States)

    Rajasekariah, G R; Dhage, K R; Deb, B N; Bose, S

    1985-03-01

    Two-day-old baby hamsters were infected initially with the infective larvae of hamster-adapted human hookworm, Necator americanus (NaL3). After a specified period they were again infected orally with infective larvae of Ancylostoma ceylanicum (AcL3). Three weeks after the second infection they were killed and the establishment of N. americanus and A. ceylanicum was assessed. The effect of different infection levels and exposure period of N. americanus on the concurrent establishment of A. ceylanicum was also examined. An infection with 50 NaL3 percutaneously, and 3 weeks later, a second infection with 50 AcL3 orally has produced reasonably equal number of hookworms (no statistical difference in the burden of N. americanus and A. ceylanicum) in the intestine of hamsters. Thus this protocol of dual infection was found suitable to develop two species of hookworms in hamsters for anthelmintic screening.

  12. Feeding Your Baby

    Medline Plus

    Full Text Available ... In This Topic Breastfeeding help Breastfeeding is best Food allergies and baby Formula feeding How to breastfeed Keeping a breastfeeding log Keeping breast milk safe and healthy Problems and discomforts when breastfeeding Starting your baby on solid foods Using a breast pump Baby Feeding your baby ...

  13. Feeding Your Baby

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    Full Text Available ... Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & birth Postpartum care Baby ... Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & birth Postpartum care Baby ...

  14. Safe Sleep for Babies

    Science.gov (United States)

    ... 5 MB] Read the MMWR Science Clips Safe Sleep for Babies Eliminating hazards Recommend on Facebook Tweet ... Page Problem Every year, there are thousands of sleep-related deaths among babies. View large image and ...

  15. Feeding Your Baby

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    Full Text Available ... and your partner to bond with her. Breast milk is the best food for your baby during ... life. Learn how to breastfeed and why breast milk is so good for babies. You and your ...

  16. Feeding Your Baby

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  17. Feeding Your Baby

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  18. Feeding Your Baby

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    Full Text Available ... Nutrition, weight & fitness Prenatal care Is it safe? Labor & birth Postpartum care Baby Caring for your baby ... Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth The newborn intensive care unit (NICU) ...

  19. Feeding Your Baby

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    Full Text Available ... so good for babies. You and your baby may need time and practice to get comfortable breastfeeding, ... t be afraid to ask for help ; you may just need a little extra time and support ...

  20. Choosing Safe Baby Products

    Science.gov (United States)

    ... confusing, especially with all the new gadgets and features available (not to mention the many product recalls). ... Gates Choosing Safe Baby Products: Infant Seats & Child Safety Seats (Car Seats) Choosing Safe Baby Products: Playpens Choosing Safe ...

  1. Choosing Safe Baby Gear

    Science.gov (United States)

    ... attaches to the wall. Do not use the diamond-shaped, accordion-style gates. Your child can be ... raises the risk of SIDS. As the baby grows, guidelines recommend having the baby face out, rather ...

  2. Feeding Your Baby

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  3. Feeding Your Baby

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  4. Feeding Your Baby

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  5. Caring for Your Premature Baby

    Science.gov (United States)

    ... feeding your baby. Breast milk is the best baby food. If your baby does not suck or latch ... solid food. Most doctors advise giving a premature baby solid food at 4 to 6 months after the baby’s ...

  6. Baby supplies you need

    Science.gov (United States)

    Newborn care - baby supplies ... easiest for changing diapers and cleaning baby up. Mittens for the baby's hands to keep them from ... Carlo WA. The newborn infant. In: Kliegman RM, Stanton BF, St Geme ... NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, ...

  7. Feeding Your Baby

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  8. Breastfeed Your Baby

    Science.gov (United States)

    ... In fact, giving babies things like rice cereal, baby food, or formula during the first 6 months can ... may help answer some of your questions. My baby really doesn't need other food or liquid for the first 6 months? Right. ...

  9. Feeding Your Baby

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    Full Text Available ... opportunities Our corporate partners In Your Area Tools & Resources Careers Events in your area Frequently asked questions Email sign up Join our online community Home > Baby > Feeding your baby Feeding your baby E-mail to a friend Please fill in all ...

  10. The New Baby.

    Science.gov (United States)

    Brain, Helen

    This book for beginning readers tells the story of a South African priest and his wife who are ashamed when their daughter tells them she is going to have a baby. They refuse to have anything to do with her when she is pregnant. However, when the baby comes, everything changes and they come to accept and love the baby. Large black and white…

  11. Baby M: babies (and justice) for sale.

    Science.gov (United States)

    Annas, G J

    1987-06-01

    A professor of health law criticizes the decisions of New Jersey Superior Court Judge Harvey R. Sorkow which culminated in his awarding permanent custody of Baby M to her biological father, William Stern. Annas quotes from the In re Baby M decision and from the contract between Stern and his wife and surrogate mother Mary Beth Whitehead to support his contention that Sorkow "rendered a sermon filled with contradictions, double-standards, inapt analogies, and unsupported conclusions." He argues that legally Mrs. Whitehead could not have prospectively waived her right to rear a child she bore, that Sorkow was biased in favor of the "upper-middle-class Sterns," and that consideration should be given to returning Baby M to Mrs. Whitehead. He urges state legislatures to outlaw the sale of children, to affirm the legal status of the gestational mother, and to forbid a surrogate's relinquishment of parental rights until after her child's birth.

  12. Shaken Baby Syndrome

    Science.gov (United States)

    ... vomiting, and pale or bluish skin. Shaken baby injuries usually occur in children younger than 2 years old, but may be ... vomiting, and pale or bluish skin. Shaken baby injuries usually occur in children younger than 2 years old, but may be ...

  13. T P Nafeesa Baby

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. T P Nafeesa Baby. Articles written in Pramana – Journal of Physics. Volume 80 Issue 2 February 2013 pp 289-294 Research Articles. Plasma excitations in a single-walled carbon nanotube with an external transverse magnetic field · K A Vijayalakshmi T P Nafeesa Baby.

  14. Resuscitation of Newborn Babies

    African Journals Online (AJOL)

    Ann Burgess

    If the baby is still not breathing give inflation breaths – see Box 1. The heart rate usually responds to lung inflation. If there is no heart rate response, check for chest movement. About 95% of babies needing resuscitation will recover within a minute or two once air enters the lungs. • Re-assess. If the lungs are inflating (i.e. the.

  15. Baby Bath Basics

    Science.gov (United States)

    ... the bath. Most parents start with the baby's face and move down to dirtier parts of the body. This keeps rinsed areas from getting soapy again. If your newborn has hair and you think it needs washing, go ahead. With your free hand gently massage a drop of mild baby shampoo into your ...

  16. Feeding Your Baby

    Medline Plus

    Full Text Available ... your baby Feeding your baby E-mail to a friend Please fill in all fields. Please enter a valid e-mail address. Your information: Your recipient's ... Sign up to save this page. Saving Just a moment, please. You've saved this page It's ...

  17. Baby Poop: What's Normal?

    Science.gov (United States)

    ... I'm breast-feeding my newborn and her bowel movements are yellow and mushy. Is this normal for baby poop? Answers from Jay L. Hoecker, M.D. Yellow, mushy bowel movements are perfectly normal for breast-fed babies. Still, ...

  18. Cytotoxicity of municipal solid waste incinerator ash wastes toward mammalian kidney cell lines.

    Science.gov (United States)

    Huang, Wu-Jang; Tsai, Jia-Lin; Liao, Ming-Huei

    2008-05-01

    In this study, three municipal solid waste incinerator (MSWI) ash wastes-bottom ash, scrubber residue, and baghouse ash-were extracted using a toxicity characteristic leaching procedure (TCLP) extractant. These so-called final TCLP extracts were applied to African green monkey kidney cells (Vero), baby hamster kidney cells (BHK-21), and pig kidney cells (PK-15), multi-well absorption reader analysis was performed to test how the cytotoxicity of the incineration ashes would affect the digestive systems of animals. Ion-coupled plasma analyses indicated that the baghouse ash extract possessed the highest pH and heavy metal concentration, its cytotoxicity was also the highest. In contrast, the bottom ash and the scrubber residue exhibited very low cytotoxicities. The cytotoxicities of mixtures of baghouse ash and scrubber residue toward the three tested cell lines increased as the relative ratio of the baghouse ash increased, especially for the Vero cells. The slight cytotoxicity of the scrubber residue arose mainly from the presence of Cr species, whereas the high cytotoxicity of the baghouse ash resulted from its high content of heavy metals and alkali ions. In addition, it appears that the dissolved total organic carbon content of these ash wastes can reduce the cytotoxicity of ash wastes that collect in animal cells.

  19. Feeding Your Baby

    Medline Plus

    Full Text Available ... Global Map Premature Birth Report Cards Careers Archives Health Topics Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & birth Postpartum care Baby ...

  20. Your Baby's First Vaccines

    Science.gov (United States)

    ... babies younger than 3 months of age. Hib ( Haemophilus influenzae type b) Signs and symptoms can include fever, ... be recommended for travel to certain countries. Hib ( Haemophilus influenzae type b) 3 or 4 2 months, 4 ...

  1. Feeding Your Baby

    Medline Plus

    Full Text Available ... You and your baby may need time and practice to get comfortable breastfeeding, but you’ll get ... and tools to have healthier pregnancies. By uniting communities, we're building a brighter future for us ...

  2. Feeding Your Baby

    Medline Plus

    Full Text Available ... Frequently asked questions Email sign up Join our online community March for Babies Nacersano Share Your Story OUR CAUSE HEALTH TOPICS RESEARCH & PROFESSIONALS MEDIA GET INVOLVED DONATE Our mission Fighting ...

  3. Bringing Your Baby Home

    Science.gov (United States)

    ... arrives later (perhaps after a stay in the neonatal intensive care unit ), or comes through an adoption ... heart rate, and you may be taught infant cardiopulmonary resuscitation (CPR) . But whether your baby is full-term ...

  4. Feeding Your Baby

    Medline Plus

    Full Text Available ... your baby during the first year of life. Learn how to breastfeed and why breast milk is ... little extra time and support to get started. Learn what you can do if you have breastfeeding ...

  5. Feeding Your Baby

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    Full Text Available ... Content] March For Babies | Nacersano | Share Your Story Register | Sign In Hi | Your dashboard | sign out Donate ... DONATE sign up sign in sign out account center my dashboard Our Cause Our mission Fighting premature ...

  6. Feeding Your Baby

    Medline Plus

    Full Text Available ... Saving Just a moment, please. You've saved this page It's been added to your ... milk is the best food for your baby during the first year of life. Learn how to breastfeed and why ...

  7. Your Premature Baby

    Science.gov (United States)

    ... babies have to spend time in a hospital’s neonatal intensive care unit (also called NICU). This is ... air sacs in the lungs from collapsing. Intraventricular hemorrhage (IVH) . This is bleeding in the brain. It ...

  8. Laundering Your Baby's Clothes

    Science.gov (United States)

    ... Liquid detergents can rinse out easier than powder detergents, so might be better for sensitive skin.) Unless your baby has allergies , eczema/atopic dermatitis , or another condition causing sensitive ...

  9. Feeding Your Baby

    Medline Plus

    Full Text Available ... in sign out account center my dashboard Our Cause Our mission Fighting premature birth: The Prematurity Campaign ... March for Babies Nacersano Share Your Story OUR CAUSE HEALTH TOPICS RESEARCH & PROFESSIONALS MEDIA GET INVOLVED DONATE ...

  10. Feeding Your Baby

    Medline Plus

    Full Text Available ... health research Prematurity research centers For providers NICU Family Support® ... with her. Breast milk is the best food for your baby during the first year of life. Learn how to breastfeed and why breast milk ...

  11. Feeding Your Baby

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    Full Text Available ... us on Twitter Instagram: behind the scenes Our research Research grants Prematurity research Birth defects research Infant ... bond with her. Breast milk is the best food for your baby during the first year of ...

  12. Feeding Your Baby

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    Full Text Available ... this page It's been added to your dashboard . Time to eat! Feeding your baby helps her grow healthy and strong. It’s also a great time for you and your partner to bond with ...

  13. Babies Need Tummy Time

    Science.gov (United States)

    ... sharing on social media links Babies Need Tummy Time! Page Content Tummy Time is not only an ... of your baby’s normal growth. What Is Tummy Time? Tummy Time describes the times when you place ...

  14. Feeding Your Baby

    Medline Plus

    Full Text Available ... bond with her. Breast milk is the best food for your baby during the first year of ... feeding safe. And then get ready for solid foods ! In This Topic Breastfeeding help Breastfeeding is best ...

  15. Feeding Your Baby

    Medline Plus

    Full Text Available ... breastfeeding log Keeping breast milk safe and healthy Problems and discomforts when breastfeeding Starting your baby on solid ... health & safety ') document.write('') } Ask our experts! Have a ...

  16. Species difference between rat and hamster in tissue accumulation of mercury after administration of methylmercury

    International Nuclear Information System (INIS)

    Omata, Saburo; Kasama, Hidetaka; Hasegawa, Hiroshi; Hasegawa, Kazuhiro; Sugano, Hiroshi; Ozaki, Kunio

    1986-01-01

    The accumulation of mercury in tissues of the rat and hamster was determined after the administration of a single dose of 203 Hg-methylmercury chloride (10 mg/kg body weight). (1) On day 2, the mercury contents of hamster tissues were higher than those of rat tissues, except for red blood cells, in which the mercury content was about 6-fold higher in the rat than in the hamster. (2) After that time, the mercury content of hamster tissues decreased rather steeply and on day 16 it had reached 14-25% in nervous tissues and 7-15% in other tissues, of the levels on day 2. (3) In the rat, on the other hand, the mercury content of nervous tissues on day 16 was higher than that on day 2 (106-220%), except for dorsal roots and dorsal root ganglia, which showed slight decreases (75-94% of the levels on day 2). In non-neural tissues, the decreases up to day 16 were also small (71-92% of the levels on day 2). (4) Thus, both the uptake and elimination of mercury seem to be more rapid in the tissues of hamster compared with those of the rat. Similar trends of mercury accumulation and elimination were observed when animals received multiple injections of methylmercury that induced acute methylmercury intoxication. (5) Significant biotransmormation of the injected methylmercury to inorganic mercury was detected in the liver, kidney and spleen of both animal species. Although the percentages of inorganic mercury in these tissues wer not so different between the two species on day 2, they became exceedingly high in the tissues of hamster at the later stage, except in the kidney cytosol, in which the values were close in both animal species between day 2 and day 16. (orig.)

  17. Expression patterns of Doppel gene in golden hamster: quantification using real-time RT-PCR.

    Science.gov (United States)

    Li, Y R; Li, Q; Yang, J M; Zhou, X M; Yin, X M; Zhao, D M

    2008-08-01

    Doppel (prion-like protein, Dpl) may act as a useful molecular marker in tumor diagnosis and in tumor grade definition, as over-expression of Dpl protein has been found in tumors with different histologic origin. Accordingly, the quantitative analysis of the expression of Dpl in different tissues is essential for understanding its role in tumor progression and cancer diagnostic. Herein we report Dpl mRNA quantification in golden hamster by calibrated highly sensitive externally standardized real-time RT-PCR with LightCycler instrument. Total RNA was isolated from nine different organs of golden hamster in different stages of development: from neonatal to adult golden hamster. Highest level of Dpl mRNA was detected in the testis, and lower levels of Dpl mRNA were detected in the following tissues: spleen, heart, bone marrow, skeletal muscles and neocortex (only in neonatal hamster). The expression of Dpl was not detected in kidney, liver and lung. This is the first study to report the expression of Dpl in bone marrow of murine and the difference of expression levels of Dpl in testis between adult and neonatal hamsters.

  18. Ectopic Kidney

    Science.gov (United States)

    ... for a Child with Kidney Disease Nutrition for Chronic Kidney Disease in Children Growth Failure in Children with Chronic Kidney Disease Ectopic Kidney Medullary Sponge Kidney Kidney Dysplasia Ectopic ...

  19. Baby brain atlases.

    Science.gov (United States)

    Oishi, Kenichi; Chang, Linda; Huang, Hao

    2018-04-03

    The baby brain is constantly changing due to its active neurodevelopment, and research into the baby brain is one of the frontiers in neuroscience. To help guide neuroscientists and clinicians in their investigation of this frontier, maps of the baby brain, which contain a priori knowledge about neurodevelopment and anatomy, are essential. "Brain atlas" in this review refers to a 3D-brain image with a set of reference labels, such as a parcellation map, as the anatomical reference that guides the mapping of the brain. Recent advancements in scanners, sequences, and motion control methodologies enable the creation of various types of high-resolution baby brain atlases. What is becoming clear is that one atlas is not sufficient to characterize the existing knowledge about the anatomical variations, disease-related anatomical alterations, and the variations in time-dependent changes. In this review, the types and roles of the human baby brain MRI atlases that are currently available are described and discussed, and future directions in the field of developmental neuroscience and its clinical applications are proposed. The potential use of disease-based atlases to characterize clinically relevant information, such as clinical labels, in addition to conventional anatomical labels, is also discussed. Copyright © 2018. Published by Elsevier Inc.

  20. [Babies with cranial deformity].

    Science.gov (United States)

    Feijen, Michelle M W; Claessens, Edith A W M Habets; Dovens, Anke J Leenders; Vles, Johannes S; van der Hulst, Rene R W J

    2009-01-01

    Plagiocephaly was diagnosed in a baby aged 4 months and brachycephaly in a baby aged 5 months. Positional or deformational plagio- or brachycephaly is characterized by changes in shape and symmetry of the cranial vault. Treatment options are conservative and may include physiotherapy and helmet therapy. During the last two decades the incidence of positional plagiocephaly has increased in the Netherlands. This increase is due to the recommendation that babies be laid on their backs in order to reduce the risk of sudden infant death syndrome. We suggest the following: in cases of positional preference of the infant, referral to a physiotherapist is indicated. In cases of unacceptable deformity of the cranium at the age 5 months, moulding helmet therapy is a possible treatment option.

  1. Dinosaur Eggs and Babies

    Science.gov (United States)

    Carpenter, Kenneth; Hirsch, Karl F.; Horner, John R.

    1996-01-01

    In the last couple of decades the study of dinosaur eggs and babies has proved to be one of the most exciting and profitable areas of dinosaur research. This is the first book solely devoted to this topic and reviews, in scientific detail, our present state of knowledge about this exciting area of palaeontology. Chapters in the book discuss all aspects of the science including the occurrence of eggs, nests and baby skeletons, descriptive osteology of juvenile skeletons, comparative histology of juvenile bone, analyses of eggs and egg shells, palaeoenvironments of nesting sites, nesting behaviour and developmental growth of baby dinosaurs. The volume will be an invaluable addition to the book collections of vertebrate palaeontologists and their graduate students.

  2. Baby dumping and evolving baby factories in Nigeria: their ...

    African Journals Online (AJOL)

    ... approach which involves a thorough overhaul of our rigid social orientation which will create room for a conducive environment for child rights and social protection. Keywords: Baby Dumping, Child abandonment, Child Abuse, Child Right, Baby Boxes, Baby Factories, Human Trafficking, Social Protection, Stigma, Nigeria.

  3. PKU (Phenylketonuria) in Your Baby

    Science.gov (United States)

    ... health conditions > PKU (Phenylketonuria) in your baby PKU (Phenylketonuria) in your baby E-mail to a friend ... this page It's been added to your dashboard . Phenylketonuria (also called PKU) is a condition in which ...

  4. Colostrum: Your Baby's First Meal

    Science.gov (United States)

    ... Your Baby's First Meal Ages & Stages Listen Español Text Size Email Print Share Colostrum: Your Baby's First Meal Page Content Article Body Colostrum provides all the nutrients and fluid that your newborn needs in the early days, ...

  5. Salmonella from Baby Turtles

    Centers for Disease Control (CDC) Podcasts

    2017-01-09

    Dr. Stacey Bosch, a veterinarian with CDC, discusses her article on Salmonella infections associated with baby turtles.  Created: 1/9/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 1/9/2017.

  6. CASE REPORT Mermaid baby

    African Journals Online (AJOL)

    CASE REPORT. 66. SA JOURNAL OF RADIOLOGY • September 2010. Abstract. We were recently intrigued by a baby born at Kalafong Hospital with fused lower extremities resembling a mermaid, which caused us to search for the background and origin of this entity called sirenomelia. Case report. A 40-year-old woman ...

  7. Feeding Your Baby

    Medline Plus

    Full Text Available ... Global Map Premature Birth Report Cards Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? ... Feeding your baby Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth The newborn intensive ...

  8. Feeding Your Baby

    Medline Plus

    Full Text Available ... Global Map Premature Birth Report Cards Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? ... baby Common illnesses Family health & safety Complications & Loss Pregnancy complications Preterm labor & premature birth The newborn intensive ...

  9. Feeding Your Baby

    Medline Plus

    Full Text Available ... mail was sent. Save to my dashboard Sign in or Sign up to save this page. Saving Just a moment, please. You've saved this page It's been added to your dashboard . Time to eat! Feeding your baby helps her grow ...

  10. The Blue Baby Syndrome

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 10. The Blue Baby Syndrome - Nitrate Poisoning in Humans. Deepanjan Majumdar. General Article Volume 8 Issue 10 October 2003 pp 20-30. Fulltext. Click here to view fulltext PDF. Permanent link:

  11. How Babies Think

    Science.gov (United States)

    Bachleda, Amelia R.; Thompson, Ross A.

    2018-01-01

    Babies think differently than adults, and understanding how they think can help us see their explosive brain growth in everyday behavior. Infants learn language faster than adults do, use statistics to understand how the world works, and even reason about the minds of others. But these achievements can be hidden by their poor self-regulatory…

  12. Market analysis baby food Ukraine

    OpenAIRE

    A.A. Voronina; I.Z. Dolzhanskiy

    2010-01-01

    The paper analyzes the development of baby food industry in Ukraine and abroad due the increased level of fertility, unmet needs of baby food products in the growing demand for intervention and strengthening foreign manufacturers. Special attention is paid to government regulation and legislation of the relevant Ukrainian market of baby food.

  13. Boosting Your Baby's Brain Power

    Science.gov (United States)

    Engel-Smothers, Holly; Heim, Susan M.

    2009-01-01

    With more than 100 billion neurons that would stretch more than 60,000 miles, a newborn baby's brain is quite phenomenal! These neurons must generally form connections within the first eight months of a baby's life to foster optimal brain growth and lifelong learning. Mommies, daddies, and caregivers are extremely vital to ensuring babies reach…

  14. Baby Naps: Daytime Sleep Tips

    Science.gov (United States)

    ... won't harm your baby. It's common for babies to cry when put down for sleep, but most will quiet themselves if left alone for a few minutes. If the crying lasts longer than a few minutes, check on your baby and offer comforting words. Then give him or ...

  15. Shaken baby syndrome; Shaken-baby-Syndrom

    Energy Technology Data Exchange (ETDEWEB)

    Reith, W.; Ahlhelm, F.; Papanagiotou, P. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany); Rohrer, T. [Universitaetsklinikum des Saarlandes, Klinik fuer Allgemeine Paediatrie und Neonatologie, Homburg/Saar (Germany)

    2009-10-15

    Shaken baby syndrome (SBS) describes the coincidence of subdural hematoma, retinal bleeding and, disadvantageous for the prognosis, diffuse brain damage caused by powerful shaking of the infant. The clinical symptoms include irritability, difficulty with drinking, somnolence, apathy, cerebral cramp attacks, apnoea, temperature regulation disorders and vomiting due to cranial pressure. Milder symptoms of SBS are often not diagnosed and the number of unregistered cases is probably much greater. The diagnosis of SBS is made through the typical symptom constellation, but the lack of retinal bleeding does not exclude the diagnosis. Normally the infants are held by the thorax or upper arms and shaken in a sagittal direction during which the head falls backwards and forwards and is stopped abruptly at each extreme position. The injurious mechanism is considered to be caused by rotational forces which force tissue layers in the brain against each other and also lead to rupture of bridging veins between the skull and the brain. The prognosis is poor and approximately 25% of infants die of SBS within days or weeks. Approximately 75% of survivors suffer from long term damage with physical handicaps, limitations in hearing, visual disturbances up to blindness and mental disorders or combinations of these conditions. Prevention is therefore the most important aspect. (orig.) [German] Das Shaken-baby-Syndrom (SBS) oder Schuetteltrauma des Saeuglings beschreibt die Koinzidenz subduraler Haematome, retinaler Blutungen und prognostisch unguenstiger, diffuser Hirnschaeden durch heftiges Schuetteln eines Saeuglings. Die klinischen Symptome umfassen Irritabilitaet, Trinkschwierigkeiten, Somnolenz, Apathie, zerebrale Krampfanfaelle, Apnoe, Temperaturregulationsstoerungen und Erbrechen durch Hirndruck. Leichtere Symptome des SBS werden haeufig nicht diagnostiziert, die Dunkelziffer ist wahrscheinlich viel hoeher. Die Diagnose des SBS wird durch die typische Symptomkonstellation gestellt

  16. LAMELLAR ICHTHYOSIS (COLLODION BABY

    Directory of Open Access Journals (Sweden)

    Paramarta IGE

    2012-11-01

    Full Text Available The ichthyosis are a heterogeneous group of hereditary and acquired disorder of keratinization which affected the epidermis characterized by presence of visible scales on the skin surface in the absence of inflammation. It can occur as a disease limited to the skin or in association with abnormalities of other organ systems. Lamelar ihthyosis (LI is one of two mayor autosomal recessive ichthyosis with an incidence of approximately one in 300,000. The diagnosis is based on clinical and pathologic finding. Infection is the most common complication, while prognosis of LI is depends on severity and complication of the disease. A case of lamellar ichthyosis in 0 day Balinese female baby was reported. The skin of the body was thick, plate-like appearance, scaling on the entire body, some of the thick skin was ruptured on chest and extremities. There were eclabium on the mouth and ectropion on the eyes. Histopathology examination showed hyperkeratosis without perivascular infiltration lymphocyte. The baby was given breast feeding, antibiotic, hydrocortisone cream and olium olivarum. The prognosis of the baby is good.

  17. Polymyopathy in a Syrian golden hamster

    NARCIS (Netherlands)

    Wijnands, M.V.W.; Woutersen, R.A.

    1996-01-01

    A Syrian golden hamster suffered from general swelling of skeletal muscles. At microscopical observation the muscle tissue exhibited degeneration and necrosis, as well as regenerative features. The inflammatory response was very slight. The histopathological lesions were diagnosed as polymyopathy.

  18. Induction of lyme arthritis in LSH hamsters

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, J.L.; Schell, R.F.; Hejka, A.; England, D.M.; Konick, L.

    1988-09-01

    In studies of experimental Lyme disease, a major obstacle has been the unavailability of a suitable animal model. We found that irradiated LSH/Ss Lak hamsters developed arthritis after injection of Borrelia burgdorferi in the hind paws. When nonirradiated hamsters were injected in the hind paws with B. burgdorferi, acute transient synovitis was present. A diffuse neutrophilic infiltrate involved the synovia and periarticular structures. The inflammation was associated with edema, hyperemia, and granulation tissue. Numerous spirochetes were seen in the synovial and subsynovial tissues. The histopathologic changes were enhanced in irradiated hamsters. The onset and duration of the induced swelling were dependent on the dose of radiation and the inoculum of spirochetes. Inoculation of irradiated hamsters with Formalin-killed spirochetes or medium in which B. burgdorferi had grown for 7 days failed to induce swelling. This animal model should prove useful for studies of the immune response to B. burgdorferi and the pathogenesis of Lyme arthritis.

  19. Track segment studies with Chinese hamster cells

    International Nuclear Information System (INIS)

    Bird, R.P.

    1984-01-01

    Survival curves of near-diploid and near-tetraploid Chinese hamster cell cultures following irradiation by an 241 Am α source indicate different growth rates for the two clones. Possible reasons for the difference are discussed

  20. Proteomic Analysis of Chinese Hamster Ovary Cells

    DEFF Research Database (Denmark)

    Baycin-Hizal, Deniz; Tabb, David L.; Chaerkady, Raghothama

    2012-01-01

    To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions obtained from gel electrophoresis, multidimens......To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions obtained from gel electrophoresis...

  1. Persistence of experimental Rocio virus infection in the golden hamster (Mesocricetus auratus

    Directory of Open Access Journals (Sweden)

    Daniele Freitas Henriques

    2012-08-01

    Full Text Available Rocio virus (ROCV is an encephalitic flavivirus endemic to Brazil. Experimental flavivirus infections have previously demonstrated a persistent infection and, in this study, we investigated the persistence of ROCV infection in golden hamsters (Mesocricetus auratus. The hamsters were infected intraperitoneally with 9.8 LD50/0.02 mL of ROCV and later anaesthetised and sacrificed at various time points over a 120-day period to collect of blood, urine and organ samples. The viral titres were quantified by real-time-polymerase chain reaction (qRT-PCR. The specimens were used to infect Vero cells and ROCV antigens in the cells were detected by immunefluorescence assay. The levels of antibodies were determined by the haemagglutination inhibition technique. A histopathological examination was performed on the tissues by staining with haematoxylin-eosin and detecting viral antigens by immunohistochemistry (IHC. ROCV induced a strong immune response and was pathogenic in hamsters through neuroinvasion. ROCV was recovered from Vero cells exposed to samples from the viscera, brain, blood, serum and urine and was detected by qRT-PCR in the brain, liver and blood for three months after infection. ROCV induced histopathological changes and the expression of viral antigens, which were detected by IHC in the liver, kidney, lung and brain up to four months after infection. These findings show that ROCV is pathogenic to golden hamsters and has the capacity to cause persistent infection in animals after intraperitoneal infection.

  2. Obesity without overeating in golden hamsters.

    Science.gov (United States)

    Wade, G N

    1982-10-01

    When male golden hamsters were switched from a diet of Purina rodent chow to a calorically-dense high-fat diet or were given ad lib access to a 32% sucrose solution in addition to chow, they adjusted their food intakes rapidly (within 24 hr) and did not overeat. Nevertheless, the fat-fed hamsters tripled their rate of weight gain and nearly doubled their carcass fat content after one month on the diet. Resting oxygen consumption (animals awake but quite) was significantly lower in fat-fed animals than in chow-fed controls. Sucrose feeding had no effect on food intake, body weight gain, carcass composition or oxygen consumption. Thus, whereas rats exhibit dietary obesity in spite of increases in energy expenditure (diet-induced thermogenesis), fat-fed hamsters seem to become obese because of decreases in energy expenditure. However, although actual energy expenditure is reduced, fat-fed hamsters exhibit an enhanced thermogenic capacity. Interscapular brown adipose tissue mass, protein content, and DNA content as well as norepinephrine-stimulated oxygen consumption were all significantly elevated in fat-fed hamsters. The significance of these concurrent diet-induced decreases in energy expenditure and increases in thermogenic capacity is not clear, but they could be of some value in preparing the hamster for winter.

  3. Recognition of a Baby's Emotional Cry towards Robotics Baby Caregiver

    Directory of Open Access Journals (Sweden)

    Shota Yamamoto

    2013-02-01

    Full Text Available We developed a method for pattern recognition of baby's emotions (discomfortable, hungry, or sleepy expressed in the baby's cries. A 32-dimensional fast Fourier transform is performed for sound form clips, detected by our reported method and used as training data. The power of the sound form judged as a silent region is subtracted from each power of the frequency element. The power of each frequency element after the subtraction is treated as one of the elements of the feature vector. We perform principal component analysis (PCA for the feature vectors of the training data. The emotion of the baby is recognized by the nearest neighbor criterion applied to the feature vector obtained from the test data of sound form clips after projecting the feature vector on the PCA space from the training data. Then, the emotion with the highest frequency among the recognition results for a sound form clip is judged as the emotion expressed by the baby's cry. We successfully applied the proposed method to pattern recognition of baby's emotions. The present investigation concerns the first stage of the development of a robotics baby caregiver that has the ability to detect baby's emotions. In this first stage, we have developed a method for detecting baby's emotions. We expect that the proposed method could be used in robots that can help take care of babies.

  4. Kidney Dysplasia

    Science.gov (United States)

    ... as the fetus grows in the womb. In kidney dysplasia, the tubules fail to branch out completely. Urine that would ... to form a network of tiny structures called tubules. Kidney dysplasia in one kidney What are the kidneys ...

  5. Kidney transplant

    Science.gov (United States)

    ... place a healthy kidney into a person with kidney failure . ... Renal transplant; Transplant - kidney ... Becker Y, Witkowski P. Kidney and pancreas transplantation. In: Townsend CM ... Urology . 11th ed. Philadelphia, PA: Elsevier; 2016: ...

  6. Baby-Crying Acceptance

    Science.gov (United States)

    Martins, Tiago; de Magalhães, Sérgio Tenreiro

    The baby's crying is his most important mean of communication. The crying monitoring performed by devices that have been developed doesn't ensure the complete safety of the child. It is necessary to join, to these technological resources, means of communicating the results to the responsible, which would involve the digital processing of information available from crying. The survey carried out, enabled to understand the level of adoption, in the continental territory of Portugal, of a technology that will be able to do such a digital processing. It was used the TAM as the theoretical referential. The statistical analysis showed that there is a good probability of acceptance of such a system.

  7. Cystolithiasis in a Syrian hamster: a different outcome | Petrini ...

    African Journals Online (AJOL)

    Considering the positive outcome and the beneficial properties of palmitoylethanolamide, glucosamine, and hesperidin, these nutritional elements in Syrian hamsters, are recommended to reduce recurrence after surgical treatment of urolithiasis. Keywords: Glucosamine, Hamster, Hesperidin, PEA, Urolithiasis ...

  8. Methods for modeling chinese hamster ovary (cho) cell metabolism

    DEFF Research Database (Denmark)

    2015-01-01

    Embodiments of the present invention generally relate to the computational analysis and characterization biological networks at the cellular level in Chinese Hamster Ovary (CHO) cells. Based on computational methods utilizing a hamster reference genome, the invention provides methods...

  9. Production and purification of polyclonal anti-hamster ...

    African Journals Online (AJOL)

    . ... IgG showed high titer and high specificity in the designed ELISA. Purified antibody and its conjugation with HRP are used in research and diagnosis of hamster disease. Key words: Production, purification, hamster immunoglobulins.

  10. Protect Yourself and Your Baby from Dengue

    Science.gov (United States)

    ... Aedes aegypti mosquitoes • A pregnant woman infected with dengue virus may infect her unborn baby or her newborn baby at birth » Harmful effects of dengue virus infection include death of the unborn baby, low ...

  11. Having a Baby (Especially for Teens)

    Science.gov (United States)

    ... Patients About ACOG Having a Baby (Especially for Teens) Home For Patients Search FAQs Having a Baby ( ... 2015 PDF Format Having a Baby (Especially for Teens) Especially For Teens What is prenatal care? What ...

  12. Baby-MIND neutrino detector

    Science.gov (United States)

    Mefodiev, A. V.; Kudenko, Yu. G.; Mineev, O. V.; Khotjantsev, A. N.

    2017-11-01

    The main objective of the Baby-MIND detector (Magnetized Iron Neutrino Detector) is the study of muon charge identification efficiency for muon momenta from 0.3 to 5 GeV/ c. This paper presents the results of measurement of the Baby-MIND parameters.

  13. Your Premature Baby: Low Birthweight

    Science.gov (United States)

    ... placenta grows in your uterus and supplies your baby with food and oxygen through the umbilical cord. Some problems ... about what you can do to help your baby be healthy. As your child grows, make sure she eats healthy food, stays active and goes to all her health ...

  14. Healthy Smile for Your Baby

    Science.gov (United States)

    ... hot. Use a different spoon to taste your baby’s food. If your baby’s bottle nipple or pacifier falls ... foods like sugar, honey, or syrup. Give Your Baby Healthy Foods m Breast milk is best! Breastfeed your baby ...

  15. Monitoring your baby before labor

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000485.htm Monitoring your baby before labor To use the sharing features on ... what the results mean for you and your baby. Alternative Names Prenatal care - monitoring; Pregnancy care - monitoring; Non-stress test - monitoring; NST- ...

  16. Histopathology of Lyme arthritis in LSH hamsters

    Energy Technology Data Exchange (ETDEWEB)

    Hejka, A.; Schmitz, J.L.; England, D.M.; Callister, S.M.; Schell, R.F.

    1989-05-01

    The authors studied the histopathologic evolution of arthritis in nonirradiated and irradiated hamsters infected with Borrelia burgdorferi. Nonirradiated hamsters injected in the hind paws with B. burgdorferi developed an acute inflammatory reaction involving the synovium, periarticular soft tissues, and dermis. This acute inflammatory reaction was short-lived and was replaced by a mild chronic synovitis as the number of detectable spirochetes in the synovium, periarticular soft tissues, and perineurovascular areas diminished. Exposing hamsters to radiation before inoculation with B. burgdorferi exacerbated and prolonged the acute inflammatory phase. Spirochetes also persisted longer in the periarticular soft tissues. A major histopathologic finding was destructive and erosive bone changes of the hind paws, which resulted in deformation of the joints. These studies should be helpful in defining the immune mechanism participating in the onset, progression, and resolution of Lyme arthritis.

  17. Pharmacokinetics and tissue distribution of Antimony after multiple intramuscular administrations in the Hamster

    International Nuclear Information System (INIS)

    Al-Jaser, May H.; Radwan, Mahasen A.; Zaghloul, Imam Y.

    2006-01-01

    The fate of pentavalent antimony (Sb) in different tissues in the body after intramuscular administration is of great interest for the future study of Sb therapy in different sitting. Pharmacokinetics and tissue distribution of antimony (Sb) were studied in the hamster after daily dose of sodium stibogluconate equivalent to 120 mg kg of Sb, administered intramuscularly for two weeks. Liver, spleen, heart, kidney and skin tissues were isolated after blood collection at the specified time. Antimony was measured in these tissues after suitable treatment, ashing and processing, by flame less atomic absorption spectrophotometry. The concentration of Sb time profile in blood showed a linear raid decline with elimination half life (tz1/2) of 1.7h. The concentration of drug (ug/gm) declined in a biphasic manner from almost all tissues. However, the concentrations of Sb were declined in slower fashion from the hamster tissues than from the blood. The maximum concentration of Sb was determined in the kidney tissues (3416+-631ug/gm) while the lowest concentration was in the spleen (209+-187ug/gm). The maximum concentration of Sb in the kidney (ug/gm) was more than 25 fold higher than that measured from blood (ug/ml). The AUC of Sb in the studied tissues was in this rank: kidney>liver>skin>spleen>heart>blood. Surprisingly, the heart, spleen and liver showed a similar t1/2 of 5.2-6.2h while the kidney and skin had a t1/2 of about 3h. Therefore, disposition of Sb seems to kinetically follow multicompartmental compartmental model. The kidneys got the highest concentration of drug which may lead to nephrotoxicity on long term therapy. (author)

  18. Baby swimming and respiratory health.

    Science.gov (United States)

    Nystad, Wenche; Håberg, Siri E; London, Stephanie J; Nafstad, Per; Magnus, Per

    2008-05-01

    To estimate the effect of baby swimming in the first 6 months of life on respiratory diseases from 6 to 18 months. We used data from The Norwegian Mother and Child Cohort Study (MoBa) conducted by the Norwegian Institute of Public Health in children born between 1999 and 2005 followed from birth to the age of 18 months (n = 30,870). Health outcomes: lower respiratory tract infections (LRTI), wheeze and otitis media between 6 and 18 months of age. baby swimming at the age of 6 months. The effect of baby swimming was estimated by logistic regression analysis adjusting for potential confounders. About 25% of the children participated in baby swimming. The prevalence of LRTI was 13.3%, wheeze 40.0% and otitis media 30.4%. Children who were baby swimming were not more likely to have LRTI, to wheeze or to have otitis media. However, children with atopic mothers who attended baby swimming had an increased risk of wheeze, adjusted odds ratios (aOR) 1.24 (95% CI 1.11, 1.39), but not LRTI or otitis media. This was also the case for children without respiratory diseases before 6 months aOR 1.08 (95%CI 1.02-1.15). Baby swimming may be related to later wheeze. However, these findings warrant further investigation.

  19. Polycystic kidney disease

    Science.gov (United States)

    Cysts - kidneys; Kidney - polycystic; Autosomal dominant polycystic kidney disease; ADPKD ... kidneys may be needed. Treatments for end-stage kidney disease may include dialysis or a kidney transplant .

  20. Recognition of a Baby's Emotional Cry Towards Robotics Baby Caregiver

    OpenAIRE

    Yamamoto, Shota; Yoshitomi, Yasunari; Tabuse, Masayoshi; Kushida, Kou; Asada, Taro

    2013-01-01

    We developed a method for pattern recognition of baby's emotions (discomfortable, hungry, or sleepy) expressed in the baby's cries. A 32-dimensional fast Fourier transform is performed for sound form clips, detected by our reported method and used as training data. The power of the sound form judged as a silent region is subtracted from each power of the frequency element. The power of each frequency element after the subtraction is treated as one of the elements of the feature vector. We per...

  1. China's baby boomers.

    Science.gov (United States)

    Heise, L

    1988-01-01

    China's birthrate increased from 18 births/1000 population in 1985 to 21/1000 in 1986, after a decade of steady decline. In 1971, to avoid a projected population of 2.4 billion by 2050, Chinese leaders launched the "later-longer-fewer" campaign. Men and women were encouraged to postpone marriage until their mid- to late-20s, to allow 4 years between pregnancies, and to limit their families to 2 children. The standards were slightly more lenient in the rural areas. Together, the campaign was responsible for a reduction in the total fertility rate from 5.9 births/woman in 1970 to 2.7 births in 1979. Yet, due to the age structure of the population, with 39% of Chinese under age 15, even replacement-level fertility was bound to generate growth for decades. Consequently, in 1979, the post-Mao leadership inaugurated the "1-child" policy, a program designed to limit the Chinese population to 1.2 billion by 2000. Family planning has become a state sanctioned and monitored activity. The policy is implemented via public education, persuasion, peer pressure, and a series of incentives and penalties. In this context, the question arises as to what caused China's birthrate to rise. A major factor is the effect of the country's youth-dominated age structure. Following the Great Leap Forward (1958-60) and the prolonged accompanying famine, the birthrate increased markedly as couples conceived the children they had postponed. These baby boomers, born from 1962-64, now are having their own babies. About 1/3 of the 1986 increase in births may be accounted for by the ripple effect of this relatively large cohort finally reaching reproductive age. Further, the age of 1st reproduction has declined recently in response to the Marriage Law of 1980, which lowers the legal marriage age. Another influence has been a gradual yet significant relaxation in some of the basic tenets of the 1-child policy. In 1984, the government reaffirmed the critical importance of family planning but increased

  2. Nipah virus transmission in a hamster model.

    Directory of Open Access Journals (Sweden)

    Emmie de Wit

    2011-12-01

    Full Text Available Based on epidemiological data, it is believed that human-to-human transmission plays an important role in Nipah virus outbreaks. No experimental data are currently available on the potential routes of human-to-human transmission of Nipah virus. In a first dose-finding experiment in Syrian hamsters, it was shown that Nipah virus was predominantly shed via the respiratory tract within nasal and oropharyngeal secretions. Although Nipah viral RNA was detected in urogenital and rectal swabs, no infectious virus was recovered from these samples, suggesting no viable virus was shed via these routes. In addition, hamsters inoculated with high doses shed significantly higher amounts of viable Nipah virus particles in comparison with hamsters infected with lower inoculum doses. Using the highest inoculum dose, three potential routes of Nipah virus transmission were investigated in the hamster model: transmission via fomites, transmission via direct contact and transmission via aerosols. It was demonstrated that Nipah virus is transmitted efficiently via direct contact and inefficiently via fomites, but not via aerosols. These findings are in line with epidemiological data which suggest that direct contact with nasal and oropharyngeal secretions of Nipah virus infected individuals resulted in greater risk of Nipah virus infection. The data provide new and much-needed insights into the modes and efficiency of Nipah virus transmission and have important public health implications with regards to the risk assessment and management of future Nipah virus outbreaks.

  3. Nipah Virus Transmission in a Hamster Model

    Science.gov (United States)

    de Wit, Emmie; Bushmaker, Trenton; Scott, Dana; Feldmann, Heinz; Munster, Vincent J.

    2011-01-01

    Based on epidemiological data, it is believed that human-to-human transmission plays an important role in Nipah virus outbreaks. No experimental data are currently available on the potential routes of human-to-human transmission of Nipah virus. In a first dose-finding experiment in Syrian hamsters, it was shown that Nipah virus was predominantly shed via the respiratory tract within nasal and oropharyngeal secretions. Although Nipah viral RNA was detected in urogenital and rectal swabs, no infectious virus was recovered from these samples, suggesting no viable virus was shed via these routes. In addition, hamsters inoculated with high doses shed significantly higher amounts of viable Nipah virus particles in comparison with hamsters infected with lower inoculum doses. Using the highest inoculum dose, three potential routes of Nipah virus transmission were investigated in the hamster model: transmission via fomites, transmission via direct contact and transmission via aerosols. It was demonstrated that Nipah virus is transmitted efficiently via direct contact and inefficiently via fomites, but not via aerosols. These findings are in line with epidemiological data which suggest that direct contact with nasal and oropharyngeal secretions of Nipah virus infected individuals resulted in greater risk of Nipah virus infection. The data provide new and much-needed insights into the modes and efficiency of Nipah virus transmission and have important public health implications with regards to the risk assessment and management of future Nipah virus outbreaks. PMID:22180802

  4. Effect of mebendazole on fibrosarcoma in hamsters

    African Journals Online (AJOL)

    1Department of Histology and Embryology, 2Department of Pharmacy, 3Department of Pharmacology, Toxicology and Clinical. Pharmacology ... Purpose: To investigate the effect of mebendazole on an in vivo solid tumor model of fibrosarcoma in hamsters. ..... cancer [16] and one case report of colon cancer. [14] can be ...

  5. Kidney Failure

    Science.gov (United States)

    ... enough red blood cells. This is called kidney failure. If your kidneys fail, you need treatment to ... providers, family, and friends, most people with kidney failure can lead full and active lives. NIH: National ...

  6. Kidney Problems

    Science.gov (United States)

    ... High Blood Pressure Nutrition Join our e-newsletter! Aging & Health A to Z Kidney Problems Basic Facts & ... specialize in the care of people with kidney (renal) diseases are called nephrologists . What are Kidney Diseases? ...

  7. Kidney Transplant

    Science.gov (United States)

    ... Menu Menu Search Home Prevention Kidney Disease Patients Organ Donation & Transplantation Professionals Events Advocacy Donate A to Z Health ... Tests for Transplant Care After Kidney Transplant Common Organ Donation and Transplantation Terms The National Kidney Foundation (NKF) is the ...

  8. Kidney Diseases

    Science.gov (United States)

    ... until you go to the bathroom. Most kidney diseases attack the nephrons. This damage may leave kidneys ... medicines. You have a higher risk of kidney disease if you have diabetes, high blood pressure, or ...

  9. Kidney Cancer

    Science.gov (United States)

    ... urine until it is peed out. What Causes Kidney and Renal Pelvis Cancers? Smoking is the most important risk ... grease from metal. What Are the Symptoms of Kidney and Renal Pelvis Cancers? A person with kidney or renal ...

  10. Comparative study of the toxic effects of gallium arsenide, indium arsenide and arsenic trioxide following intratracheal instillations to the lung of Syrian golden hamsters.

    Science.gov (United States)

    Tanaka, A; Hirata, M; Omura, M; Zhao, M; Makita, Y; Yamazaki, K; Inoue, N; Gotoh, K

    2000-01-01

    Toxic effects of gallium arsenide (GaAs), indium arsenide (InAs) and arsenic trioxide (As2O3) were studied in male Syrian golden hamsters. GaAs (7.7 mg/kg) and As2O3 (1.3 mg/kg) particles were instilled intratracheally twice a week a total of 16 times, while InAs (7.7 mg/kg) was instilled a total of 14 times. As a control, hamsters were treated with the vehicle, phosphate buffer solution. During the instillation period, the cumulative body weight gain of the InAs-, but not the GaAs- or As2O3-treated hamsters was suppressed significantly, when compared with the control group. Slight to severe inflammatory responses were observed in the lung for all treatment groups. The most severe inflammatory change, characterized by an accumulation of neutrophils and macrophages, exudation, thickness of the pleura and fibrotic proliferation was found in the InAs-treated hamsters. Extensive alveolar or bronchiolar cell hyperplasia with or without keratinizing squamous cell metaplasia was observed in almost all the InAs-treated hamsters. Furthermore, squamous cell metaplasia or squamous cell hyperplasia developed in some of the InAs-treated hamsters, but not in the GaAs- or As2O3-treated hamsters. Slight to mild lesions were found in the convoluted tubules of the kidney in both the GaAs and InAs groups. From the present study, the toxic potency of these particles was provisionally estimated to be in the following order: InAs > GaAs > As2O3, at the dosage level used in this study. Furthermore, there was evidence that InAs particles could induce pulmonary, renal or systemic toxicity, and as such, InAs particles may produce pulmonary precancerous change when instilled intratracheally into hamsters.

  11. Collodion Baby - a Case Report

    Directory of Open Access Journals (Sweden)

    Stojanović Vesna

    2014-12-01

    Full Text Available Colloidon baby describes a highly characteristic clinical entity in newborns encased in a yellowish translucent membrane resembling collodion. In most cases the condition either precedes the development of one of a variety of ichthyoses, the commonest of which are lamellar ichthyosis and non-bullous ichthyosiform erythroderma, or occasionally represents an initial phase of other ichthyoses such as ichthyosis vulgaris. In at least 10% of all cases of collodion baby, the condition is followed by a mild ichthyosis of lamellar type, so mild as to be considered more or less normal, so-called self-healing collodion baby or ‘lamellar ichthyosis of the newborn’. In this report we present a rare case of collodion baby in whom, after collodion membrane peeled-off, the skin retained normal appearance.

  12. Your Baby's Growth: 3 Months

    Science.gov (United States)

    ... on a standardized growth chart (there are different charts for boys and girls). Whether your baby is large, small, or medium-sized, as long as this growth pattern stays consistent over time, chances are everything is ...

  13. Baby's Head Shape: What's Normal?

    Science.gov (United States)

    ... conservative and helmet therapy for positional cranial deformation. Plastic and Reconstructive Surgery. In press. Accessed Dec. 19, ... infant-and-toddler-health/in-depth/healthy-baby/art-20045964 . Mayo Clinic Footer Legal Conditions and Terms ...

  14. [Manufactured baby food: safety expectations].

    Science.gov (United States)

    Davin, L; Van Egroo, L-D; Galesne, N

    2010-12-01

    Food safety is a concern for parents of infants, and healthcare professionals are often questioned by them about this topic. Baby food European regulation ensures high levels of safety and is more rigorous than common food regulation. Maximal limit for pesticides in baby food demonstrates the high level of requirements. This limit must be below the 10 ppb detection threshold, whatever the chemical used. Other contaminants such as nitrates are also the subject of greater expectations in baby food. Food safety risks control needs a specific know-how that baby food manufacturers have acquired and experienced, more particularly by working with producers of high quality raw material. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

  15. Positioning your baby for breastfeeding

    Science.gov (United States)

    ... knees snug against your body. If your nipple hurts, see if your baby has slipped down and ... Rasmussen KM. Breastfeeding and health outcomes for the mother-infant dyad. Pediatr Clin North Am . 2013;60( ...

  16. Shaken baby syndrome

    International Nuclear Information System (INIS)

    Reith, W.; Ahlhelm, F.; Papanagiotou, P.; Rohrer, T.

    2009-01-01

    Shaken baby syndrome (SBS) describes the coincidence of subdural hematoma, retinal bleeding and, disadvantageous for the prognosis, diffuse brain damage caused by powerful shaking of the infant. The clinical symptoms include irritability, difficulty with drinking, somnolence, apathy, cerebral cramp attacks, apnoea, temperature regulation disorders and vomiting due to cranial pressure. Milder symptoms of SBS are often not diagnosed and the number of unregistered cases is probably much greater. The diagnosis of SBS is made through the typical symptom constellation, but the lack of retinal bleeding does not exclude the diagnosis. Normally the infants are held by the thorax or upper arms and shaken in a sagittal direction during which the head falls backwards and forwards and is stopped abruptly at each extreme position. The injurious mechanism is considered to be caused by rotational forces which force tissue layers in the brain against each other and also lead to rupture of bridging veins between the skull and the brain. The prognosis is poor and approximately 25% of infants die of SBS within days or weeks. Approximately 75% of survivors suffer from long term damage with physical handicaps, limitations in hearing, visual disturbances up to blindness and mental disorders or combinations of these conditions. Prevention is therefore the most important aspect. (orig.) [de

  17. The LHC babies

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    With the machine restart and first collisions at 3.5 TeV, 2009 and 2010 were two action-packed years at the LHC. The events were a real media success, but one important result that remained well hidden was the ten births in the LHC team over the same period. The mothers – engineers, cryogenics experts and administrative assistants working for the LHC – confirm that it is possible to maintain a reasonable work-life balance. Two of them tell us more…   Verena Kain (left) and Reyes Alemany (right) in the CERN Control Centre. With the LHC running around the clock, LHC operations engineers have high-pressure jobs with unsociable working hours. These past two years, which will undoubtedly go down in the annals of CERN history, the LHC team had their work cut out, but despite their high-octane professional lives, several female members of the team took up no less of a challenge in their private lives, creating a mini-baby-boom by which the LHC start-up will also be remembe...

  18. Comparison of the pathogenicity of Nipah virus isolates from Bangladesh and Malaysia in the Syrian hamster.

    Directory of Open Access Journals (Sweden)

    Blair L DeBuysscher

    Full Text Available Nipah virus is a zoonotic pathogen that causes severe disease in humans. The mechanisms of pathogenesis are not well described. The first Nipah virus outbreak occurred in Malaysia, where human disease had a strong neurological component. Subsequent outbreaks have occurred in Bangladesh and India and transmission and disease processes in these outbreaks appear to be different from those of the Malaysian outbreak. Until this point, virtually all Nipah virus studies in vitro and in vivo, including vaccine and pathogenesis studies, have utilized a virus isolate from the original Malaysian outbreak (NiV-M. To investigate potential differences between NiV-M and a Nipah virus isolate from Bangladesh (NiV-B, we compared NiV-M and NiV-B infection in vitro and in vivo. In hamster kidney cells, NiV-M-infection resulted in extensive syncytia formation and cytopathic effects, whereas NiV-B-infection resulted in little to no morphological changes. In vivo, NiV-M-infected Syrian hamsters had accelerated virus replication, pathology and death when compared to NiV-B-infected animals. NiV-M infection also resulted in the activation of host immune response genes at an earlier time point. Pathogenicity was not only a result of direct effects of virus replication, but likely also had an immunopathogenic component. The differences observed between NiV-M and NiV-B pathogeneis in hamsters may relate to differences observed in human cases. Characterization of the hamster model for NiV-B infection allows for further research of the strain of Nipah virus responsible for the more recent outbreaks in humans. This model can be used to study NiV-B pathogenesis, transmission, and countermeasures that could be used to control outbreaks.

  19. Urethane influence in the urine formation in swiss rats and syrian hamster

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Marina F.; Silva, Natanael G.; Mesquita, Carlos Henrique de, E-mail: mflima@ipen.br, E-mail: ngsilva@ipen.br, E-mail: chmesqui@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    Urethane is an anaesthetic agent with minimal cardiovascular and respiratory system depression with long-lasting (6-10h) effects. Its carcinogenic potential avoids it from veterinary use. Either, the knowledge of its effects over the circulating catecholamines (cortisone and corticosterone), with reflects in the muscles physiology, it is widely used in pharmacological studies in laboratory species. At the first minutes, Urethane induces a hyperglycaemia condition due the insulin concentration decrease, later than, the insulin concentration and the condition becomes in hypoglycaemia, but the Urethane interfering in the urine production mechanisms has not been described. It is accepted that the glycolic level would not interferes in the kidney function, except in chronic states, notably associated with insulin related diseases. The relative high biological half-life of {sup 177}Lu-Dotatate allows its use in biodistribution studies among small animals whose metabolic rates are so fast that would be impossible observe them with the most part of the labeled molecules. During the performance of a cross-species extrapolation study using Urethane as anaesthesia and {sup 177}Lu-Dotatate as metabolic tracer, was observed the Urethane influence over urine formation in Swiss rats and Syrian hamster (Mesocricetus auratus). The objective of this work is only describes the Urethane action over the urine production. Firstly, four male inbread Wistar Swiss rats ({+-}250 g), are anesthetized, with around 1200 mg/kg, i.p., in groups of two. One rat from each group get ahead to the injection of {sup 177}Lu-Dotatate and Gamma camera in vivo study, the second ones, anesthetized, waited under warming lights until more than one hour to initiate the biodistribution study. The scintillographical images shown the radiopeptide stopped at the kidneys and the urinary empty in the animals who attempt more than one hour before enter to radiopharmaceutical injection and Gamma camera imaging

  20. Urethane influence in the urine formation in swiss rats and syrian hamster

    International Nuclear Information System (INIS)

    Lima, Marina F.; Silva, Natanael G.; Mesquita, Carlos Henrique de

    2011-01-01

    Urethane is an anaesthetic agent with minimal cardiovascular and respiratory system depression with long-lasting (6-10h) effects. Its carcinogenic potential avoids it from veterinary use. Either, the knowledge of its effects over the circulating catecholamines (cortisone and corticosterone), with reflects in the muscles physiology, it is widely used in pharmacological studies in laboratory species. At the first minutes, Urethane induces a hyperglycaemia condition due the insulin concentration decrease, later than, the insulin concentration and the condition becomes in hypoglycaemia, but the Urethane interfering in the urine production mechanisms has not been described. It is accepted that the glycolic level would not interferes in the kidney function, except in chronic states, notably associated with insulin related diseases. The relative high biological half-life of 177 Lu-Dotatate allows its use in biodistribution studies among small animals whose metabolic rates are so fast that would be impossible observe them with the most part of the labeled molecules. During the performance of a cross-species extrapolation study using Urethane as anaesthesia and 177 Lu-Dotatate as metabolic tracer, was observed the Urethane influence over urine formation in Swiss rats and Syrian hamster (Mesocricetus auratus). The objective of this work is only describes the Urethane action over the urine production. Firstly, four male inbread Wistar Swiss rats (±250 g), are anesthetized, with around 1200 mg/kg, i.p., in groups of two. One rat from each group get ahead to the injection of 177 Lu-Dotatate and Gamma camera in vivo study, the second ones, anesthetized, waited under warming lights until more than one hour to initiate the biodistribution study. The scintillographical images shown the radiopeptide stopped at the kidneys and the urinary empty in the animals who attempt more than one hour before enter to radiopharmaceutical injection and Gamma camera imaging procedures. The rates

  1. Quantum entanglement of baby universes

    International Nuclear Information System (INIS)

    Aganagic, Mina; Okuda, Takuya; Ooguri, Hirosi

    2007-01-01

    We study quantum entanglements of baby universes which appear in non-perturbative corrections to the OSV formula for the entropy of extremal black holes in type IIA string theory compactified on the local Calabi-Yau manifold defined as a rank 2 vector bundle over an arbitrary genus G Riemann surface. This generalizes the result for G=1 in hep-th/0504221. Non-perturbative terms can be organized into a sum over contributions from baby universes, and the total wave-function is their coherent superposition in the third quantized Hilbert space. We find that half of the universes preserve one set of supercharges while the other half preserve a different set, making the total universe stable but non-BPS. The parent universe generates baby universes by brane/anti-brane pair creation, and baby universes are correlated by conservation of non-normalizable D-brane charges under the process. There are no other source of entanglement of baby universes, and all possible states are superposed with the equal weight

  2. Baby-Boom, Baby-Bust and the Great Depression

    OpenAIRE

    Andriana BELLOU; Emanuela CARDIA

    2015-01-01

    The baby-boom and subsequent baby-bust have shaped much of the history of the second half of the 20th century; yet it is still largely unclear what caused them. This paper presents a new unified explanation of the fertility Boom-Bust that links the latter to the Great Depression and the subsequent economic recovery. We show that the 1929 Crash attracted young married women 20 to 34 years old in 1930 (whom we name D-cohort) in the labor market possibly via an added worker effect. Using several...

  3. Dominant white spotting in the Chinese hamster.

    Science.gov (United States)

    Henwood, C; Henwood, J; Robinson, R

    1987-01-01

    An autosomal dominant white spotting mutant is described for the Chinese hamster. The mutant gene is designated as dominant spot (symbol Ds). The homozygote DsDs is a prenatal lethal while the heterozygote Ds + displays white spotting. The expression of white is variable, ranging from a white forehead spot to extensive white on the body. The venter is invariably white. Growth appears to be normal and the fertility of both sizes shows no impairment.

  4. Oxytocin inhibits aggression in female Syrian hamsters.

    Science.gov (United States)

    Harmon, A C; Huhman, K L; Moore, T O; Albers, H E

    2002-12-01

    Dominant subordinate relationships are formed as the result of social conflict and are maintained at least in part by communication. At this time, little is known about the neural mechanisms that are responsible for coordinating the social behaviours (e.g. aggression) that occur in association with the formation and maintenance of these relationships. The purpose of the present study was to investigate the role of oxytocin (OXT) within the medial preoptic anterior hypothalamic continuum (MPOA-AH) in the control of aggression in female hamsters. OXT injected into the MPOA-AH immediately before testing significantly reduced the duration of aggression in a dose-dependent manner. Injection of an OXT antagonist 30 min before testing significantly increased the duration of aggression. In contrast, the duration of aggression was not altered when hamsters were tested either 30 min after injection of OXT or immediately following injection of an OXT-antagonist. These data support the hypothesis that OXT release within the MPOA-AH regulates social behaviours important in the formation and maintenance of dominant subordinate relationships in female hamsters.

  5. Designer babies--why not?

    Science.gov (United States)

    Evans, M

    2001-02-01

    Though many objections can be levelled against the idea of the practice of genetic intervention to produce 'designer babies', upon examination they are shown to hinge on features which concern parental intentions towards their children, rather than features specific to the means involved. These intentions may be pursued by a variety of social practices which may, though need not, involve a measure of 'traditional' genetic selection (i.e. in terms of the identity and characteristics of the reproducing partners). This paper reviews a number of these objections and, by parity of reasoning, rejects their claim to count specifically or decisively against genetic intervention in pursuit of 'designer babies'. Rejecting these objections does not lead to the endorsement of 'designing babies, but it shows that any unease must be grounded elsewhere and defended by other arguments.

  6. Baby MIND Experiment Construction Status

    Energy Technology Data Exchange (ETDEWEB)

    Antonova, M.; et al.

    2017-04-28

    Baby MIND is a magnetized iron neutrino detector, with novel design features, and is planned to serve as a downstream magnetized muon spectrometer for the WAGASCI experiment on the T2K neutrino beam line in Japan. One of the main goals of this experiment is to reduce systematic uncertainties relevant to CP-violation searches, by measuring the neutrino contamination in the anti-neutrino beam mode of T2K. Baby MIND is currently being constructed at CERN, and is planned to be operational in Japan in October 2017.

  7. Akachan ni Kanpai! Celebrating the baby: Baby, family, culture.

    Science.gov (United States)

    Watanabe, Hisako

    2011-01-01

    "Akachan ni Kanpai! Celebrating the Baby: Baby, Family, Culture" was the theme of the 11th World Congress of the World Association for Infant Mental Health (August 2008). It denotes every baby's right to be blessed from the beginning of life, whether the baby is healthy, ill, disabled, or born into unwelcoming social contexts. Across the world, modern families of the 21st century face increasingly stressful lives. Japan, with a rapid postwar social change, has yielded increasing cases of postnatal depression and abuse, alerting her to reevaluate amae, a cultural affinity for interdependency. Amae, as studied by Takeo Doi, originates in the mother--infant relationship and is carried through into adulthood characterizing Japanese mentality. The Japanese values for things simple, small, slow, and silent are typical in the art of haiku and Noh, but also render significant in infant mental health. Infants born under impossible conditions, such as those born extremely small and with congenital anomalies, survive through simple, sincere, sensitive care imbued with respect to their subtle signs. Their narratives of slow and steady progress from despair to a loving family context urge us to say "Akachan ni Kanpai" to countless infants worldwide whose voices are yet to be heard. Copyright © 2011 Michigan Association for Infant Mental Health.

  8. 29 BABY DUMPING AND EVOLVING BABY FACTORIES IN NIGERIA

    African Journals Online (AJOL)

    various purposes ranging from illegal international and domestic adoptions, rituals, slave labour or sexual exploitation (Huntley, 2013). This implies that more than economic factors (poverty), the social stigma which their condition carries is a more propelling factor influencing their resort to baby factories which supposedly ...

  9. Breastfeeding FAQs: Sleep - Yours and Your Baby's

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Breastfeeding FAQs: Sleep - Yours and Your Baby's KidsHealth / For Parents / Breastfeeding FAQs: Sleep - Yours and Your Baby's What's in ...

  10. Sick Baby? When to Seek Medical Attention

    Science.gov (United States)

    Healthy Lifestyle Infant and toddler health When a healthy baby gets sick, don't panic. Understand when to ... 20, 2016 Original article: http://www.mayoclinic.org/healthy-lifestyle/infant-and-toddler-health/in-depth/healthy-baby/ ...

  11. Will Stress during Pregnancy Affect My Baby?

    Science.gov (United States)

    ... baby? Share Facebook Twitter Pinterest Email Print Will stress during pregnancy affect my baby? It is normal ... care provider during your prenatal visits. Post-Traumatic Stress Disorder (PTSD) and Pregnancy PTSD is a more ...

  12. When Your Baby Has a Birth Defect

    Science.gov (United States)

    ... Search English Español When Your Baby Has a Birth Defect KidsHealth / For Parents / When Your Baby Has ... to help you and your child. What Are Birth Defects? Birth defects (also called congenital anomalies) are ...

  13. Fetal Echocardiography/Your Unborn Baby's Heart

    Science.gov (United States)

    ... Artery Disease Venous Thromboembolism Aortic Aneurysm More Fetal Echocardiography / Your Unborn Baby's Heart Updated:Oct 6,2016 ... Your Risk • Symptoms & Diagnosis Introduction Common Tests Fetal Echocardiography/Your Unborn Baby's Heart - Fetal Echocardiogram Test - Detection ...

  14. Your Baby's Growth: 12 Months

    Science.gov (United States)

    ... concerned your baby has slowed growth or a drop in weight, the doctor may ask these questions: Has your ... Crawling, cruising, and walking will burn calories, so weight gain might not be as ... the spoon on the floor than eating? The world is a fascinating place, ...

  15. Babies, Toddlers and the Media.

    Science.gov (United States)

    Fenichel, Emily, Ed.

    2001-01-01

    "Zero to Three" is a single-focus bulletin of the National Center for Infants, Toddlers, and Families providing insight from multiple disciplines on the development of infants, toddlers, and their families. Noting that America's babies and toddlers live in a world full of television sets, VCRs, computers, videogames, and interactive…

  16. Kidney Failure

    Science.gov (United States)

    ... The Hope Affair A Pairing for Prevention - Boston Classical Music For a Cause A Pairing for Prevention - ... kidney Financial Assistance Kidney patient assistance HelpLine Grants Management System (GMS) login Education & Research Patient Webinars Become ...

  17. Kidney stones

    Science.gov (United States)

    ... be done include: Blood tests to check calcium, phosphorus, uric acid, and electrolyte levels Kidney function tests ... half an inch (1.25 centimeters) that are located in the kidney or ureter. It uses sound ...

  18. Kidney School

    Science.gov (United States)

    ... Listen Printing multiple copies? Read our licensing agreement Sexuality and Fertility Maintaining a healthy sex life and ... run. Take Our Survey! Sponsors Help Keep Kidney School Free Visit Our Sponsors Page Kidney School is ...

  19. Kidney biopsy

    Science.gov (United States)

    ... Results A normal result is when the kidney tissue shows normal structure. What Abnormal Results Mean An abnormal result means there are changes in the kidney tissue. This may be due to: Infection Poor blood ...

  20. Feeding patterns and diet -- babies and infants

    Science.gov (United States)

    ... time digesting cow's milk. Do not feed your baby any solid food until 4 to 6 months old. Your baby ... away or by not opening their mouth. Your baby begins showing interest in food when others are eating. When to Call the ...

  1. Collodion baby: A report of 4 cases

    African Journals Online (AJOL)

    owner

    2012-12-28

    Dec 28, 2012 ... decent. The abnormal appearances of the babies' skin were all no- ticed at birth. ... mal appearance of the baby's skin was noticed at birth. Baby was delivered at home but mother presented im- .... autosomal recessive fashion.16 Placental insufficiency and post maturity have also been implicated in some.

  2. Production and purification of polyclonal anti-hamster ...

    African Journals Online (AJOL)

    user

    2011-01-17

    Jan 17, 2011 ... Purified antibody and its conjugation with HRP are used in research and diagnosis of hamster disease. Key words: Production, purification, hamster immunoglobulins. INTRODUCTION. Polyclonal antibodies represent a group or mixture of antibodies produced by different B-lymphocytes in res- ponse to the ...

  3. Radiation-induced anorexia in Syrian hamsters

    International Nuclear Information System (INIS)

    Kindt, A.; Sattler, E.L.; Schraub, A.

    1980-01-01

    The recovery of Syrian hamsters after split dose application (interval 11 days) was studied on the basis of the weight response and of food uptake. Two periods of weight loss and anorexia can be distinguished, an early one immediately after irradiation and a secondary one 6-10 days later. The secondary response is a function of the radiation dose and allows to distinguish survivors from non-survivors, since it is much more pronounced and longerlasting in the latter than in the former. The first response appears not to be influenced by a previous conditioning irradiation. (orig.) [de

  4. ["Designer baby" changed to French for "double hope baby"].

    Science.gov (United States)

    Fagniez, P-L; Loriau, J; Tayar, C

    2005-10-01

    Scientific advances during the last decades regarding potential intervention on embryos arouse many questions in society to prepare the ground concerning the limits that should be set for these practices. For the first time in 1994, a parliamentary proceeding allowed the definition of a French model of bioethics through laws of the same name. These laws, among others, authorized in a well and strictly defined setting the practice of preimplantation genetic diagnosis (PGD). Because of technical progress concerning PGD, new questions arose, especially concerning the accomplishment of designer babies. The French Chamber of Representatives came in with a new law that banishes the concept of designer babies and replaces it with another concept: double hope babies, in French "bébé du double espoir". A first hope of a pregnancy giving birth to a healthy child and the second being that this child conceived with the aid of PGD could help treat an elder brother. Because of the issuing of two specific laws in a ten years interval, France occupies a privileged place in a Europe where bioethical issues continue to be debated, particularly PGD.

  5. Polycystic Kidney Disease

    Science.gov (United States)

    ... Eating, Diet, & Nutrition for PKD Race, Ethnicity, & Kidney Disease Renal Artery Stenosis Renal Tubular Acidosis Simple Kidney Cysts ... sodium. Related Conditions & Diseases Chronic Kidney Disease Kidney Disease in Children Simple Kidney Cysts Kidney Stones Urinary Tract Infections ...

  6. A modified anxious behavior test for hamsters.

    Science.gov (United States)

    Shannonhouse, John L; York, Daniel C; Morgan, Caurnel

    2014-01-15

    Latency to feed in a novel environment assesses anxious behavior in rodents, but it is unclear whether it distinguishes anxiety from consumption or appetite. The anxiety-related feeding/exploration conflict (AFEC) test was used here to assess anxious behavior in Syrian hamsters for which increased cheek-pouching of food, but not overconsumption of it, reflects appetitive drive, and orexigenic stimuli do not increase consumption. The setup of the test prevented cheek-pouching. Latency to approach test food provided an additional control for non-emotional effects of treatments. Feed and approach latencies in the test cage were normalized to those in the home cage to factor out non-emotional effects. Feed latency and the feed latency ratio (test cage/home cage) were reduced by acute treatment with benzodiazepine, diazepam, or beta-adrenergic receptor antagonist, propranolol, or chronic treatment with norepinephrine reuptake inhibitor, desipramine. Reductions of feed latency and the feed latency ratio were not associated with hyperphagia, and these behaviors were unaltered by acute treatment with opioid receptor antagonist, naltrexone. Latency to approach food in the test cage, with and without normalization, was unaltered by these treatments. Finally, overnight fasting elevated feed latency without hyperphagia, and this effect was attenuated by chronic desipramine treatment. These results suggest that the AFEC test assesses anxious, but not appetitive or consummatory, behavior, and that its sensitivity increases with food deprivation of hamsters. Copyright © 2013. Published by Elsevier B.V.

  7. Uptake of elemental mercury and activity of catalase in rat, hamster, guinea-pig, normal and acatalasemic mice

    International Nuclear Information System (INIS)

    Eide, I.; Syversen, T.L.M.

    1982-01-01

    Uptake of elemental mercury after inhalation (3.5 mg/m 3 ) and the activity of catalase in brain, liver, kidney and blood were investigated in rat, hamster, guinea-pig, and normal and acatalasemic mice. The uptake of mercury in the species investigated varied considerably, being highest in the two strains of mice, followed by rat and hamster, and lowest in the guinea-pig. The uptake seemed to be more dependent on pulmonary ventilation than on the activity of catalase. The two strains of mice were exposed to a wide range of mercury concentrations in air (0.002-3.5 mg/m 3 ). The content of mercury in brain, liver and kidney was linearly dependent on the mercury concentration in the air, whereas in blood this relationship was exponential. At the lower concentraions of mercury in the inhaled air, the mercury level in blood was significantly lower, and in kidney higher in the acatalasemic mice compared to the normal ones. In acatalasemic mice the mercury content in the liver has higher at all concentrations investigated, whereas in brain no difference between the two strains was found. (author)

  8. Universal acquired melanosis (Carbon baby

    Directory of Open Access Journals (Sweden)

    Kaviarasan P

    2008-01-01

    Full Text Available We report a 3-year-old girl born with fair complexion which became darker. The color change was insidious in onset at the age of 5 months, asymptomatic and progressive involving the entire body surface. Histopathology revealed increased pigmentation of the epidermal basal layer. Universal acquired melanosis is a rare form of hypermelanosis which was synonymously referred to as "Carbon baby". This is a rare presentation with only one earlier case report.

  9. Spontaneous adrenal hemorrhage during pregnancy: a case with horseshoe kidney

    Directory of Open Access Journals (Sweden)

    Mohadeseh Amini

    2017-11-01

    Full Text Available Spontaneous adrenal hemorrhage is an acute hemorrhage during pregnancy, which can be tragic for the mother and the baby. We report a unique spontaneous hemorrhage during pregnancy in a case with horseshoe kidney with separated adrenal, presented for the first time in the world. Computed tomography scan showed a horseshoe kidney fused with left normal kidney. Interestingly the adrenal gland was remained in right flank and separated from the horseshoe kidney, which prepares a probable physical stress for the hemorrhage. Diagnosis and surgery were done successfully and the case was fully recovered after several days.

  10. Effects of policosanols and phytosterols on lipid levels and cholesterol biosynthesis in hamsters.

    Science.gov (United States)

    Wang, Y W; Jones, P J H; Pischel, I; Fairow, C

    2003-02-01

    The current study was carried out to examine the effects of policosanols and phytosterols, alone and in combination, on lipid profiles, cholesterol biosynthesis, and tissue histopathological changes in hamsters. Fifty male Golden Syrian hamsters, weighing 100 to 120 g, were fed a regular rodent chow for 2 wk before being randomly assigned into 5 groups of 10 animals each fed semisynthetic diets for 4 wk. Group 1 was given a control diet that contained 0.25% cholesterol and 5% fat with a PUFA to saturated FA ratio of 0.4. Groups 2 to 5 were fed the control diet and given Octa-6 [a policosanol mixture from sugar cane wax, 25 mg/kg body weight (BW)], Ricewax (a policosanol mixture from rice wax with 50% being converted to the corresponding acids, 50 mg/kg BW), phytosterols (Cholestatin; 1,000 mg/kg BW), and Ricewax (50 mg/kg BW) plus phytosterols (1,000 mg/kg BW), respectively. The results showed that there was no difference between Octa-6 and Ricewax treatments in any of the lipid parameters measured, and both had similar levels of triglyceride (TG), total cholesterol (T-C), and HDL cholesterol (HDL-C) as the control. Octa-6 but not Ricewax increased (P = 0.03) non-HDL-C as compared with the control. Phytosterols reduced T-C (P < 0.0003) and HDL-C (P < 0.004) without a significant effect on TG and non-HDL-C as compared to the control. Ricewax plus phytosterols had effects similar to those with phytosterols alone. Free cholesterol synthetic rates were not different among the treatments. Policosanols or phytosterols did not show any toxic effects in liver, heart, brain, or kidney. Results suggest that, although phytosterols reduce T-C and HDL-C levels, policosanols have no significant favorable effect in changing lipid levels in hamsters.

  11. Kisspeptin and the seasonal control of reproduction in hamsters

    DEFF Research Database (Denmark)

    Simonneaux, Valérie; Ansel, Laura; Revel, Florent G

    2008-01-01

    -expressing neurons, which were recently shown to be implicated in the regulation of GnRH release. Hamsters are seasonal rodents which are sexually active in long photoperiod and quiescent in short photoperiod. The photoperiodic information is transmitted to the reproductive system by melatonin, a pineal...... in the arcuate nucleus of the Syrian hamster is lower in short photoperiod, when animals are sexually quiescent. Notably, intracerebroventricular infusion of Kiss1 gene product, kisspeptin, in hamsters kept in short photoperiod is able to override the inhibitory photoperiod and to reactivate sexual activity...

  12. Expression and Distribution of Leptospiral Outer Membrane Components during Renal Infection of Hamsters

    Science.gov (United States)

    Barnett, Jeanne K.; Barnett, Dean; Bolin, Carole A.; Summers, Theresa A.; Wagar, Elizabeth A.; Cheville, Norman F.; Hartskeerl, Rudy A.; Haake, David A.

    1999-01-01

    The outer membrane of pathogenic Leptospira species grown in culture media contains lipopolysaccharide (LPS), a porin (OmpL1), and several lipoproteins, including LipL36 and LipL41. The purpose of this study was to characterize the expression and distribution of these outer membrane antigens during renal infection. Hamsters were challenged with host-derived Leptospira kirschneri to generate sera which contained antibodies to antigens expressed in vivo. Immunoblotting performed with sera from animals challenged with these host-derived organisms demonstrated reactivity with OmpL1, LipL41, and several other proteins but not with LipL36. Although LipL36 is a prominent outer membrane antigen of cultivated L. kirschneri, its expression also could not be detected in infected hamster kidney tissue by immunohistochemistry, indicating that expression of this protein is down-regulated in vivo. In contrast, LPS, OmpL1, and LipL41 were demonstrated on organisms colonizing the lumen of proximal convoluted renal tubules at both 10 and 28 days postinfection. Tubular epithelial cells around the luminal colonies had fine granular cytoplasmic LPS. When the cellular inflammatory response was present in the renal interstitium at 28 days postinfection, LPS and OmpL1 were also detectable within interstitial phagocytes. These data establish that outer membrane components expressed during infection have roles in the induction and persistence of leptospiral interstitial nephritis. PMID:9916100

  13. Piper species protect cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters.

    Science.gov (United States)

    Agbor, Gabriel A; Akinfiresoye, Luli; Sortino, Julianne; Johnson, Robert; Vinson, Joe A

    2012-10-01

    Pre-clinical and clinical studies points to the use of antioxidants as an effective measure to reduce the progression of oxidative stress related disorders. The present study evaluate the effect of three Piper species (Piper guineense, Piper nigrum and Piper umbellatum) for the protection of cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters. Hamsters were classified into eight groups: a normal control, atherogenic control and six other experimental groups (fed atherogenic diet supplemented with different doses of P. nigrum, P. guineense and P. umbellatum (1 and 0.25 g/kg) for 12 weeks. At the end of the feeding period the heart, liver and kidney from each group were analyzed for lipid profile and antioxidant enzymes activities. Atherogenic diet induced a significant (PPiper species significantly inhibited the alteration effect of atherogenic diet on the lipid profile and antioxidant enzymes activities. The Piper extracts may possess an antioxidant protective role against atherogenic diet induced oxidative stress in cardiac, hepatic and renal tissues. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. MODERN PRODUCTS FOR FEEDING PREMATURE BABIES

    Directory of Open Access Journals (Sweden)

    A. V. Surzhik

    2012-01-01

    Full Text Available In recent decades there has been substantial progress in the technology of premature infants nursing, especially with extremely low birth weight. Adequate feeding is one of the fundamental factors of premature babies nursing. To ensure a premature baby with all necessary components for power saving in breast milk intake, breast milk fortifiers — specifically developed additives that adjust the composition of food for premature babies, are used for more than 20 years (for premature babies receiving breast milk. On the one hand, to preserve all benefits of breastfeeding, on the other — to prevent the deficit development of necessary elements for adequate growth and development of nutrients.

  15. 7 CFR 319.56-43 - Baby corn and baby carrots from Zambia.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Baby corn and baby carrots from Zambia. 319.56-43... § 319.56-43 Baby corn and baby carrots from Zambia. (a) Immature, dehusked “baby” sweet corn (Zea mays L..., which is a field, where the corn has been grown must have been inspected at least once during the...

  16. Kidney Infection

    Science.gov (United States)

    ... symptoms. If you're being treated for a urinary tract infection but your signs and symptoms aren't improving, make an appointment. Severe kidney ... Seek immediate medical attention if you have kidney infection symptoms combined with ... that enter your urinary tract through the tube that carries urine from ...

  17. Kidney Stones

    Science.gov (United States)

    ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ...

  18. Chronic Kidney Disease and Kidney Failure

    Science.gov (United States)

    ... Education Visitor Information RePORT NIH Fact Sheets Home > Chronic Kidney Disease and Kidney Failure Small Text Medium Text Large Text Chronic Kidney Disease and Kidney Failure YESTERDAY One third of diabetic ...

  19. Can Babies Learn to Read? A Randomized Trial of Baby Media

    Science.gov (United States)

    Neuman, Susan B.; Kaefer, Tanya; Pinkham, Ashley; Strouse, Gabrielle

    2014-01-01

    Targeted to children as young as 3 months old, there is a growing number of baby media products that claim to teach babies to read. This randomized controlled trial was designed to examine this claim by investigating the effects of a best-selling baby media product on reading development. One hundred and seventeen infants, ages 9 to 18 months,…

  20. Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters.

    Science.gov (United States)

    I'anson, Helen; Jethwa, Preeti H; Warner, Amy; Ebling, Francis J P

    2011-06-01

    We investigated whether histaminergic tone contributes to the seasonal catabolic state in Siberian hamsters by determining the effect of ablation of histaminergic neurons on food intake, metabolic rate and body weight. A ribosomal toxin (saporin) conjugated to orexin-B was infused into the ventral tuberomammillary region of the hypothalamus, since most histaminergic neurons express orexin receptors. This caused not only 75-80% loss of histaminergic neurons in the posterior hypothalamus, but also some loss of other orexin-receptor expressing cells e.g. MCH neurons. In the long-day anabolic state, lesions produced a transient post-surgical decrease in body weight, but the hamsters recovered and maintained constant body weight, whereas weight gradually increased in sham-lesioned hamsters. VO(2) in the dark phase was significantly higher in the lesioned hamsters compared to shams, and locomotor activity also tended to be higher. In a second study in short days, sham-treated hamsters showed the expected seasonal decrease in body weight, but weight remained constant in the lesioned hamsters, as in the long-day study. Lesioned hamsters consumed more during the early dark phase and less during the light phase due to an increase in the frequency of meals during the dark and decreased meal size during the light, and their cumulative food intake in their home cages was greater than in the control hamsters. In summary, ablation of orexin-responsive cells in the posterior hypothalamus blocks the short-day induced decline in body weight by preventing seasonal hypophagia, evidence consistent with the hypothesis that central histaminergic mechanisms contribute to long-term regulation of body weight. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. Specific estrogen-induced cell proliferation of cultured Syrian hamster renal proximal tubular cells in serum-free chemically defined media

    International Nuclear Information System (INIS)

    Oberley, T.D.; Lauchner, L.J.; Pugh, T.D.; Gonzalez, A.; Goldfarb, S.; Li, S.A.; Li, J.J.

    1989-01-01

    It has long been recognized that the renal proximal tubular epithelium of the hamster is a bona fide estrogen target tissue. The effect of estrogens on the growth of proximal tubule cell explants and dissociated single cells derived from these explant outgrowths has been studied in culture. Renal tubular cells were grown on a PF-HR-9 basement membrane under serum-free chemically defined culture conditions. At 7-14 days in culture, cell number was enhanced 3-fold in the presence of either 17β-estradiol or diethylstilbestrol. A similar 3-fold increase in cell number was also seen at 1 nM 17β-estradiol in subcultured dissociated single tubular cells derived from hamster renal tubular explant outgrowths at 21 days in culture. Concomitant exposure of tamoxifen at 3-fold molar excess in culture completely abolished the increase in cell number seen with 17β-estradiol. The proliferation effect of estrogens on proximal tubular cell growth appears to be species specific since 17β-estradiol did not alter the growth of either rat or guinea pig proximal tubules in culture. In addition, at 7-10 days in culture in the presence of 17β-estradiol, [ 3 H]thymidine labeling of hamster tubular cells was enhanced 3-fold. These results clearly indicate that estrogens can directly induce primary epithelial cell proliferation at physiologic concentrations and provide strong additional evidence for an important hormonal role in the neoplastic transformation of the hamster kidney

  2. Kidney (Renal) Failure

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z Kidney Failure Kidney failure, also known as renal failure, is ... is kidney failure treated? What is kidney (renal) failure? The kidneys are designed to maintain proper fluid ...

  3. Acquired Cystic Kidney Disease

    Science.gov (United States)

    ... Eating, Diet, & Nutrition for PKD Race, Ethnicity, & Kidney Disease Renal Artery Stenosis Renal Tubular Acidosis Simple Kidney Cysts ... kidneys to develop multiple cysts. Acquired cystic kidney disease occurs in children and adults who have chronic kidney disease (CKD) — ...

  4. Development of Baby-EBM Interface System

    International Nuclear Information System (INIS)

    Mukhlis Mokhtar; Abu Bakar Ghazali; Muhammad Zahidee Taat

    2010-01-01

    This paper explains the works being done to develop an interface system for Baby-Electron Beam Machine (EBM). The function of the system is for the safety, controlling and monitoring the Baby-EBM. The integration for the system is using data acquisition (DAQ) hardware and LabVIEW to develop the software. (author)

  5. MONITORING BABY INCUBATOR SENTRAL DENGAN KOMUNIKASI WIRELESS

    Directory of Open Access Journals (Sweden)

    Ary Sulistyo Utomo

    2018-04-01

    180m. Pengujian suhu ruang baby incubator menggunakan termometer sebagai perbandingan dengan nilai suhu yang dibaca pada alat. Dari pengukuran diperoleh tingkat perbedaan 0% pada suhu 30oC dan 2,8% pada suhu 37oC.   Kata kunci: baby incubator, sistem monitoring sentral, microsoft visual studio, arduino.

  6. Preparing Your Family for a New Baby

    Science.gov (United States)

    ... can be very helpful. So can sibling classes (ask your hospital if it offers them). Try to tell your child before he hears about the new ... role to play in caring for the baby. Tell her she can hold the baby, although she must ask you first. Praise her when she is gentle ...

  7. Newborn Screening Tests for your Baby

    Science.gov (United States)

    ... oxygen in your baby’s blood by using a sensor attached to his finger or foot. This test is used to screen babies for a group of heart conditions called critical congenital heart disease (CCHD). Your baby gets this test before he ...

  8. Welcoming a New Baby into Your Family

    Science.gov (United States)

    ... play peek-a-boo with you. They're just getting adjusted to the world. In time, your baby sister or brother will be able ... good time to ask your mom or dad to spend a little time together — just the two of you. When a new baby ...

  9. Three-parent baby: is it ethical?

    Science.gov (United States)

    Dahiya, Neha; Garg, Suneela

    2017-11-14

    The UK was the first country to legalise mitochondrial donation in October 2015. In 2016, the first three-parent baby was born in Mexico and the US Food and Drug Administration declared that further research on mitochondrial donation is ethically permissible. It has now become an important issue, raising as it does, the spectre of "genetically modified designer babies".

  10. Designer Babies: Eugenics Repackaged or Consumer Options?

    Science.gov (United States)

    Baird, Stephen L.

    2007-01-01

    "Designer babies" is a term used by journalists and commentators--not by scientists--to describe several different reproductive technologies. These technologies have one thing in common: they give parents more control over what their offspring will be like. Designer babies are made possible by progress in three fields: (1) Advanced…

  11. Baby Blues’ highbush blueberry

    Science.gov (United States)

    Baby Blues’ is a new highbush blueberry from the U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS) breeding program in Corvallis, OR, released in cooperation with Oregon State University’s Agricultural Experiment Station. ‘Baby Blues’ is a vigorous, high-yielding, very small-f...

  12. Motor Development Programming in Trisomic-21 Babies

    Science.gov (United States)

    Sanz, Teresa; Menendez, Javier; Rosique, Teresa

    2011-01-01

    The present study contributes to the understanding of gross motor development in babies with Down's syndrome. Also, it facilitates the comprehension of the efficiency of the early motor stimulation as well as of beginning it as early as possible. We worked with two groups of babies with Down's syndrome, beginning the early motor training in each…

  13. Teen Moms and Babies Benefit from Camping.

    Science.gov (United States)

    Goode, Marsha; Broesamle, Barbara

    1987-01-01

    Describes nine-day residential camp for Michigan teenage mothers/babies to enhance personal growth and develop responsible social skills. Outlines goals, pre-camp planning, staff, activities, evaluation. Reports 31 teen moms (ages 13-21) and 35 babies attended in 1986. Indicates participants were in therapy, experienced abuse, had low self-esteem,…

  14. Giant lower oesophageal ulcer Bushman baby

    African Journals Online (AJOL)

    1983-02-26

    Feb 26, 1983 ... Giant lower oesophageal ulcer. Bushman baby. A case report. J. J. HEYDENRYCH, A. D. KEET. •. ID a. Summary. The case of a giant, penetrating lower oesophageal ulcer in a 14-month-old Bushman baby is reported. ... crying precluded a thorough systematic examination. Food was immediately rejected.

  15. [Genotyping and evaluation of infection dynamics in a Colombian isolate of Leptospira santarosai in hamster as an experimental model].

    Science.gov (United States)

    Agudelo-Flórez, Piedad; Durango, Harold; Aranzazu, Diego; Rodas, Juan David; Travi, Bruno

    2014-01-01

    Is necessary to develop models for the study of leptospirosis. To genotype a Colombian strain of Leptospira isolated from a human with Weil´s syndrome and to evaluate its infection dynamics in the hamster experimental model. Genotyping was performed by amplification and sequence analysis of the rrs 16S and lipL32 genes. The median lethal dose was determined in intraperitoneally inoculated hamsters. The patterns of clinical chemistry, the duration of leptospiremia, leptospiruria and pathological findings were studied and compared in the same animal model infected with L. interrogans (Fiocruz L1-130). Molecular typing revealed that the isolate corresponded to the pathogenic species L. santarosai, which was recovered from hamsters´ kidneys and lungs and detected by lipL32 PCR from day 3 post-infection in these organs. There was a marked increase of C-reactive protein in animals at day 5 post-infection (3.25 mg/dl; normal value: 0.3 mg/dl) with decreases by day 18 (2.60 mg/dl: normal value: 0.8 mg/dl). Biomarkers of urea showed changes consistent with possible renal acute failure (day 5 post-infection: 49.01 mg/dl and day 18 post-infection: 53.71 mg/dl). Histopathological changes included interstitial pneumonia with varying degrees of hemorrhage and interstitial nephritis. The pathogenic species L. santarosai was identified in Colombia. Its pathogenicity as determined by tropism to lung and kidney was comparable to that of L. interrogans Fiocruz L1-130, well known for its virulence and pulmonar tropism. The biological aspects studied here had never before been evaluated in an autochthonous isolate.

  16. Resuscitating the Baby after Shoulder Dystocia

    Directory of Open Access Journals (Sweden)

    Savas Menticoglou

    2016-01-01

    Full Text Available Background. To propose hypovolemic shock as a possible explanation for the failure to resuscitate some babies after shoulder dystocia and to suggest a change in clinical practice. Case Presentation. Two cases are presented in which severe shoulder dystocia was resolved within five minutes. Both babies were born without a heartbeat. Despite standard resuscitation by expert neonatologists, no heartbeat was obtained until volume resuscitation was started, at 25 minutes in the first case and 11 minutes in the second. After volume resuscitation circulation was restored, there was profound brain damage and the babies died. Conclusion. Unsuspected hypovolemic shock may explain some cases of failed resuscitation after shoulder dystocia. This may require a change in clinical practice. Rather than immediately clamping the cord after the baby is delivered, it is proposed that (1 the obstetrician delay cord clamping to allow autotransfusion of the baby from the placenta and (2 the neonatal resuscitators give volume much sooner.

  17. Resuscitating the Baby after Shoulder Dystocia

    Science.gov (United States)

    2016-01-01

    Background. To propose hypovolemic shock as a possible explanation for the failure to resuscitate some babies after shoulder dystocia and to suggest a change in clinical practice. Case Presentation. Two cases are presented in which severe shoulder dystocia was resolved within five minutes. Both babies were born without a heartbeat. Despite standard resuscitation by expert neonatologists, no heartbeat was obtained until volume resuscitation was started, at 25 minutes in the first case and 11 minutes in the second. After volume resuscitation circulation was restored, there was profound brain damage and the babies died. Conclusion. Unsuspected hypovolemic shock may explain some cases of failed resuscitation after shoulder dystocia. This may require a change in clinical practice. Rather than immediately clamping the cord after the baby is delivered, it is proposed that (1) the obstetrician delay cord clamping to allow autotransfusion of the baby from the placenta and (2) the neonatal resuscitators give volume much sooner. PMID:27493815

  18. Kidney Transplant

    Science.gov (United States)

    ... type matches or is compatible to your own. Blood-type incompatible transplants are also possible but require additional medical treatment before and after transplant to reduce the risk of organ rejection. These are known as ABO incompatible kidney transplants. ...

  19. Kidney Facts

    Science.gov (United States)

    ... to know FAQ Living donation What is living donation? Organs Types Being a living donor First steps Being ... treatment option for kidney failure or disease through organ donation from a healthy, living person who is a ...

  20. PREBIOTICS, INULIN AND BABY FOODS

    Directory of Open Access Journals (Sweden)

    S.V. Bel’mer

    2010-01-01

    Full Text Available Prebiotics play significant role in life support of microorganisms of human gastrointestinal tract, and normal functional state of intestinal biocenosis is sufficient condition for human health. Intestinal microbiocenosis is a component of regulation of proteins and lipids metabolism, vitamins synthesis, detoxication process in intestine, etc. prebiotics include a number of disaccharides (lactulose, oligosaccharides and polysaccharides (inulin, cellulose, etc.. Fructose polymer — inulin — provides growth of bifido- and lactobacteria, improves metabolism and has immunomodulating activity. Formation of intestinal micro biocenosis in infant is provided by prebiotics of breast milk. Further state of micro biocenosis, which is necessary for growth and development of child, is determined by adequate intake of prebiotics from fruits, vegetables and cereals. It is reasonable to use special baby foods fortified with prebiotics (for example, inulin.Key words: prebiotics, intestinal microflora, inulin.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3:121-125

  1. Social context modulates food hoarding in Syrian hamsters

    Directory of Open Access Journals (Sweden)

    Bibiana Montoya

    2016-09-01

    Full Text Available The effect of the presence of a con-specific in the temporal organization of food hoarding was studied in two varieties of Syrian hamster (Mesocricetus auratus: golden and long-haired. Four male hamsters of each variety were used. Their foraging behavior was observed during four individual and four shared trials in which animals were not competing for the same food source or territory. During individual trials, long-haired hamsters consumed food items directly from the food source, transporting and hoarding only remaining pieces. During shared trials, the long-haired variety hoarded food items before consumption, and increased the duration of hoarding trips, food handling in the storage, and cache size. Golden hamsters maintained the same temporal organization of hoarding behavior (i.e., hoarding food items before consumption throughout both individual and shared trials. However, the golden variety increased handling time at the food source and decreased the duration of hoarding trips, the latency of hoarding and storing size throughout the shared trials. In Syrian hamsters, the presence of a con-specific may signal high probability of food source depletion suggesting that social pressures over food availability might facilitate hoarding behavior. Further studies are required to evaluate cost-benefit balance of food hoarding and the role of cache pilferage in this species.

  2. Hamster and Murine Models of Severe Destructive Lyme Arthritis

    Directory of Open Access Journals (Sweden)

    Erik Munson

    2012-01-01

    Full Text Available Arthritis is a frequent complication of infection in humans with Borrelia burgdorferi. Weeks to months following the onset of Lyme borreliosis, a histopathological reaction characteristic of synovitis including bone, joint, muscle, or tendon pain may occur. A subpopulation of patients may progress to a chronic, debilitating arthritis months to years after infection which has been classified as severe destructive Lyme arthritis. This arthritis involves focal bone erosion and destruction of articular cartilage. Hamsters and mice are animal models that have been utilized to study articular manifestations of Lyme borreliosis. Infection of immunocompetent LSH hamsters or C3H mice results in a transient synovitis. However, severe destructive Lyme arthritis can be induced by infecting irradiated hamsters or mice and immunocompetent Borrelia-vaccinated hamsters, mice, and interferon-gamma- (IFN-γ- deficient mice with viable B. burgdorferi. The hamster model of severe destructive Lyme arthritis facilitates easy assessment of Lyme borreliosis vaccine preparations for deleterious effects while murine models of severe destructive Lyme arthritis allow for investigation of mechanisms of immunopathology.

  3. Hamster and Murine Models of Severe Destructive Lyme Arthritis

    Science.gov (United States)

    Munson, Erik; Nardelli, Dean T.; Du Chateau, Brian K.; Callister, Steven M.; Schell, Ronald F.

    2012-01-01

    Arthritis is a frequent complication of infection in humans with Borrelia burgdorferi. Weeks to months following the onset of Lyme borreliosis, a histopathological reaction characteristic of synovitis including bone, joint, muscle, or tendon pain may occur. A subpopulation of patients may progress to a chronic, debilitating arthritis months to years after infection which has been classified as severe destructive Lyme arthritis. This arthritis involves focal bone erosion and destruction of articular cartilage. Hamsters and mice are animal models that have been utilized to study articular manifestations of Lyme borreliosis. Infection of immunocompetent LSH hamsters or C3H mice results in a transient synovitis. However, severe destructive Lyme arthritis can be induced by infecting irradiated hamsters or mice and immunocompetent Borrelia-vaccinated hamsters, mice, and interferon-gamma- (IFN-γ-) deficient mice with viable B. burgdorferi. The hamster model of severe destructive Lyme arthritis facilitates easy assessment of Lyme borreliosis vaccine preparations for deleterious effects while murine models of severe destructive Lyme arthritis allow for investigation of mechanisms of immunopathology. PMID:22461836

  4. Design and development of wireless baby monitors

    OpenAIRE

    Jen, Yi-Kuo Eric

    2008-01-01

    The Philips DAP SCD510, SCD520, SCD530, and SCD540 1.8GHz/1.9GHz DECT Digital Wireless Baby Monitors are part of the next generation digital baby monitor products that emphasize on small form factor, innovative feature set, and cost effective bill of materials. New product features include wideband audio, ambient relative humidity measurement, and carbon monoxide detection. The objectives of this project are to design and develop these four baby monitor products and begin mass production for ...

  5. Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi

    Directory of Open Access Journals (Sweden)

    Cabrine-Santos Marlene

    2003-01-01

    Full Text Available Authors describe genitourinary changes in male hamsters infected and reinfected with Trypanosoma cruzi. Changes in genital organs have been described in human and in experimental chagasic infection. Genital dysfunctions in chronic chagasic patients affect ejaculation, libido and sexual potency, and testis biopsies may show arrested maturation of germ cells, oligozoospermia and azoospermia. Sixty-five male hamsters were inoculated and reinoculated with 2x10³ trypomastigotes of T. cruzi VIC strain, and 22 non-infected animals constituted the control group. Animals were necropsied and fragments from testis, epididymis, seminal vesicle and bladder were collected and stained with hematoxylin-eosin. Peroxidase anti-peroxidase procedure was utilized to detect tissue parasitism. T. cruzi nests were found in testis, epididymis and seminal vesicle of these hamsters. Such parasitism plays a role in the origin of genital lesions observed in humans and laboratory animals during chronic chagasic infection.

  6. Arnica Tincture Cures Cutaneous Leishmaniasis in Golden Hamsters

    Directory of Open Access Journals (Sweden)

    Sara M. Robledo

    2018-01-01

    Full Text Available In search for potential therapeutic alternatives to existing treatments for cutaneous Leishmaniasis, we have investigated the effect of Arnica tincture Ph. Eur. (a 70% hydroethanolic tincture prepared from flowerheads of Arnica montana L. on the lesions caused by infection with Leishmania braziliensis in a model with golden hamsters. The animals were treated topically with a daily single dose of the preparation for 28 days. Subsequently, the healing process was monitored by recording the lesion size in intervals of 15 days up to day 90. As a result, Arnica tincture fully cured three out of five hamsters while one animal showed an improvement and another one suffered from a relapse. This result was slightly better than that obtained with the positive control, meglumine antimonate, which cured two of five hamsters while the other three showed a relapse after 90 days. This result encourages us to further investigate the potential of Arnica tincture in the treatment of cutaneous Leishmaniasis.

  7. Hamster thecal cells express muscle characteristics

    International Nuclear Information System (INIS)

    Self, D.A.; Schroeder, P.C.; Gown, A.M.

    1988-01-01

    Contraction of the follicular wall about the time of ovulation appears to be a coordinated event; however, the cells that mediate it remain poorly studied. We examined the theca externa cells in the wall of hamster follicles for the presence of a functional actomyosin system, both in developing follicles and in culture. We used a monoclonal antibody (HHF35) that recognizes the alpha and gamma isoelectric variants of actin normally found in muscle, but not the beta variant associated with non-muscle sources, to evaluate large preovulatory follicles for actin content and composition. Antibody staining of sectioned ovaries showed intense circumferential reactivity in the outermost wall of developing follicles. Immunoblots from two-dimensional gels of theca externa lysates demonstrated the presence of the two muscle-specific isozymes of actin. Immunofluorescence of cultured follicular cells pulse-labeled with [3H] thymidine (for autoradiographic detection of DNA replication) revealed the presence, in many dividing cells, of actin filaments aligned primarily along the longitudinal axis of the cells. In cultures exposed to the calcium ionophore A23187 (10(-4) M) for varying periods (5 min to 1 h), contraction of many individual muscle-actin-positive cells was observed. Immunofluorescence of these cells, fixed immediately after ionophore-induced contraction, revealed compaction of the actin filaments. Our findings demonstrate that the cells of the theca externa contain muscle actins from an early stage and that these cells are capable of contraction even while proliferating in subconfluent cultures. They suggest that follicular growth may include a naturally occurring developmental sequence in which a contractile cell type proliferates in the differentiated state

  8. Sickle Cell Disease and Your Baby

    Science.gov (United States)

    ... type of hemoglobin) from the other parent. Hemoglobin S-beta thalassemia. This condition is caused when a baby gets ... from one parent and a gene change for beta thalassemia from the other parent. How do you know ...

  9. Benzocaine and Babies: Not a Good Mix

    Science.gov (United States)

    ... Consumers Consumer Updates Benzocaine and Babies: Not a Good Mix Share Tweet Linkedin Pin it More sharing ... children are more at risk, it’s still a good idea to talk to your health care professional ...

  10. Finding a Doctor for Your New Baby

    Science.gov (United States)

    ... busy one. Along with considering baby names and buying a crib, choosing the right health care provider ... less extensively trained in children's health care. These feelings are largely unwarranted. The presence of PNPs in ...

  11. Your Baby's Development: The Third Trimester

    Science.gov (United States)

    ... fall off. You may see some of the leftover hair after your baby is born. Most of ... Categories: Family Health, Pregnancy and ChildbirthTags: Obstetrical, Pregnant Women, prenatal care October 1, 2009 Copyright © American Academy ...

  12. Help Protect Babies from Whooping Cough

    Science.gov (United States)

    ... Button Past Emails Help Protect Babies from Whooping Cough Language: English (US) Español (Spanish) Recommend on Facebook ... even knowing they have the disease. Understanding Whooping Cough Vaccines: DTaP and Tdap Two vaccines in the ...

  13. Common Cold in Babies: Symptoms and Causes

    Science.gov (United States)

    ... their coughs and sneezes, which increases your baby's risk of catching a cold. Time of year. Both children and adults are more susceptible to colds from fall to late spring. Complications Acute ear infection (otitis ...

  14. Zika Virus: Protecting Pregnant Women and Babies

    Science.gov (United States)

    ... Digital Press Kit Read the MMWR Science Clips Zika Virus Protecting Pregnant Women and Babies Language: English (US) ... Spanish) Recommend on Facebook Tweet Share Compartir Overview Zika virus infection (Zika) during pregnancy can cause damage to ...

  15. How mothers keep their babies warm.

    Science.gov (United States)

    Bacon, C J; Bell, S A; Clulow, E E; Beattie, A B

    1991-05-01

    Details of room temperature, clothing, and bedding used by night and by day and in winter and in summer were recorded for 649 babies aged 8 to 26 weeks. Room temperature at night was significantly related to outside temperature and duration of heating. Total insulation was significantly related to outside temperature and to minimum room temperature, but there was wide variation in insulation at the same room temperature. High levels of insulation for a given room temperature were found particularly at night and in winter, and were associated with the use of thick or doubled duvets and with swaddling. At least half the babies threw off some or all of their bedding at night, and at least a quarter sweated. Younger mothers and mothers in the lower social groups put more bedclothes over their babies, and the latter also kept their rooms warmer. Many mothers kept their babies warmer during infections.

  16. Your Baby's Development: The First Trimester

    Science.gov (United States)

    ... how your baby develops during the first trimester. Path to well being Pregnancy begins when a man’s ... You’ll probably feel them starting in the middle of the second trimester. After the embryonic stage, ...

  17. Pacifiers: Are They Good for Your Baby?

    Science.gov (United States)

    ... chosen a favorite pacifier, keep a few identical backups on hand. Let your baby set the pace. ... in risk of sudden infant death syndrome. Cochrane Database of Systematic Reviews. http://dx.doi.org/10. ...

  18. When Your Teen Is Having a Baby

    Science.gov (United States)

    ... Feelings Expert Answers Q&A Movies & More for Teens Teens site Sitio para adolescentes Body Mind Sexual ... Videos for Educators Search English Español When Your Teen Is Having a Baby KidsHealth / For Parents / When ...

  19. Mineral profile of Spanish commercial baby food.

    Science.gov (United States)

    Mir-Marqués, Alba; González-Masó, Anna; Cervera, M Luisa; de la Guardia, Miguel

    2015-04-01

    Commercial baby foods are an important part of the daily intake of babies from 6 to 12 months. The mineral profile of commercial baby foods in Spain was determined to establish levels of essential and non-essential elements, and their contribution to adequate intake (AI) and estimated average requirement (EAR). Thirty-five jars of commercial foods containing meat, fish, vegetables and fruit were obtained from the Spanish market and the mineral composition determined for 14 elements. In general, the baby foods analysed were sufficient for an adequate mineral intake, but contributions to AI and EAR for iron, zinc and calcium were very low (5-20%, 10-60% and 10-70%, respectively). This deficiency could be associated with growth problems or diseases in adulthood, and fortification of commercial products is recommended. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Feeding Tips For Your Baby with CHD

    Science.gov (United States)

    ... best when fed more often and on a demand schedule. They tend to tire quickly during the ... your baby. Other Liquids Avoid giving your infant water, because water has no calories. You may give ...

  1. Why lions roar like babies cry

    Science.gov (United States)

    Titze, Ingo

    2012-11-01

    When an angry lion roars, the sounds it emits can terrify anyone within earshot. But, as Ingo Titze explains, the properties of a lion's roar have some surprising similarities with those of a crying baby.

  2. Healthy Family 2009: Bringing in Baby

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues Healthy Family 2009 Bringing in Baby Past Issues / Winter 2009 ... Down syndrome and other common genetic disorders, inherited family conditions, such as Duchenne muscular dystrophy, or disorders ...

  3. A report from America: Baby M.

    Science.gov (United States)

    Rachels, James

    1987-10-01

    Rachels reviews the social and legal facts of the celebrated "Baby M" case, in which surrogate Mary Beth Whitehead attempted to keep the daughter she had borne under contract to William Stern. The first phase of the legal battle between the parents ended in March 1988, when New Jersey Superior Court Judge Harvey R. Sorkow upheld the validity of the surrogacy contract, terminated Whitehead's parental rights, and awarded custody of the child to Stern. Rachels comments on public reaction to "Baby M," on Sorkow's decision, and on the impact the case may have on legislative attempts to regulate surrogacy. He also uses the example of "Baby M," as well as that of California heart transplant patient "Baby Jesse," to discuss how the media sensationalize controversial issues.

  4. Mermaid baby | Khan | SA Journal of Radiology

    African Journals Online (AJOL)

    Abstract. We were recently intrigued by a baby born at Kalafong Hospital with fused lower extremities resembling a mermaid, which caused us to search for the background and origin of this entity called sirenomelia.

  5. Amyloidosis and Kidney Disease

    Science.gov (United States)

    ... Solitary Kidney Your Kidneys & How They Work Amyloidosis & Kidney Disease What is amyloidosis? Amyloidosis is a rare disease ... Advancement & Transfer Meetings & Workshops Health Information Diabetes Digestive Diseases Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine ...

  6. About Chronic Kidney Disease

    Science.gov (United States)

    ... Advocacy Donate A to Z Health Guide About Chronic Kidney Disease Tweet Share Print Email Chronic kidney disease (CKD) ... Learn about Glomerular Filtration Rate (GFR) What is chronic kidney disease (CKD)? Chronic kidney disease includes conditions that damage ...

  7. Chronic kidney disease

    Science.gov (United States)

    Kidney failure - chronic; Renal failure - chronic; Chronic renal insufficiency; Chronic kidney failure; Chronic renal failure ... that you do not have symptoms until your kidneys have almost ... end-stage renal disease (ESRD). At this stage, the kidneys are ...

  8. PIXE analysis by baby cyclotron

    International Nuclear Information System (INIS)

    Yoshida, Hyogo; Tanaka, Teruaki; Ito, Takashi; Toda, Yohjiro; Wakasa, Hideichiro

    1988-01-01

    The Japan Steel Works, Ltd. has been supplying a very small sized cyclotron (Baby Cyclotron) to hospitals and research facilities. The cyclotron is designed to produce short-lived radioisotopes for medical use. In the present study, this cyclotron is modified so that it can serve for PIXE analysis. The PIXE (particle induced X-ray emission) technique has the following features: (1) Down to 1 ng of trace material in a sample (mg - μg) can be detected, (2) An analysis run is completed in one to ten minutes, permitting economical analysis for a large number of samples, (3) Several elements can be analyzed simultaneously, with an almost constant sensitivity for a variety of elements ranging from aluminum to heavy metals, (4) Analysis can be performed nondestructively without a chemical process, and (5) The use of microbeam can provide data on the distribution of elements with a resolution of several μm. Software for analysis is developed to allow the modified equipment to perform peak search, background fitting, and identification and determination of peaks. A study is now being conducted to examine the performance of the equipment for PIXE analysis of thin samples. Satisfactory results have been obtained. The analysis time, excluding the background correction, is 5-10 min. (Nogami, K.)

  9. The ART of marketing babies.

    Science.gov (United States)

    Qadeer, Imrana

    2010-01-01

    New legislation can be oppressive for a significant population depending upon the politics of its drafters. The current upsurge of the surrogacy trade in India, and the label of a "win-win" situation that it has acquired, points towards an unfettered commercialisation of assisted reproductive technology and the practice of surrogacy that is blinding its middle class users as well as providers, policy makers and law makers, and charging an imagination that is already caught up in spiralling consumerism. This paper analyses the Draft Assisted Reproductive Technology (Regulation) Bill and Rules, 2008, in the Indian socioeconomic context. It identifies the interests of the affected women, and examines the contradictions of the proposed Bill with their interests, as well as with current health and population policies, confining itself to the handling of surrogacy and not the entire content of the Bill. The bases of the analytical perspective used are: the context of poverty and the health needs of the Indian population; the need to locate surrogacy services within the overall public health service context and its epidemiological basis; the need to restrain direct human experimentation for the advancement of any technology; the use of safer methods; and, finally, the rights of surrogate mothers and their babies, in India, as opposed to the compulsion or dynamics of the medical market and reproductive tourism.

  10. Safe Sleep for Babies PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2018-01-09

    This 60 second public service announcement is based on the January 2018 CDC Vital Signs report. Every year, there are about 3,500 sleep-related deaths among U.S. babies. Learn how to create a safe sleep environment for babies.  Created: 1/9/2018 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/9/2018.

  11. Exact BPS bound for noncommutative baby Skyrmions

    Energy Technology Data Exchange (ETDEWEB)

    Domrin, Andrei, E-mail: domrin@mi.ras.ru [Department of Mathematics and Mechanics, Moscow State University, Leninskie gory, 119992, GSP-2, Moscow (Russian Federation); Lechtenfeld, Olaf, E-mail: lechtenf@itp.uni-hannover.de [Institut für Theoretische Physik and Riemann Center for Geometry and Physics, Leibniz Universität Hannover, Appelstraße 2, 30167 Hannover (Germany); Linares, Román, E-mail: lirr@xanum.uam.mx [Departamento de Física, Universidad Autónoma Metropolitana Iztapalapa, San Rafael Atlixco 186, C.P. 09340, México D.F. (Mexico); Maceda, Marco, E-mail: mmac@xanum.uam.mx [Departamento de Física, Universidad Autónoma Metropolitana Iztapalapa, San Rafael Atlixco 186, C.P. 09340, México D.F. (Mexico)

    2013-11-25

    The noncommutative baby Skyrme model is a Moyal deformation of the two-dimensional sigma model plus a Skyrme term, with a group-valued or Grassmannian target. Exact abelian solitonic solutions have been identified analytically in this model, with a singular commutative limit. Inside any given Grassmannian, we establish a BPS bound for the energy functional, which is saturated by these baby Skyrmions. This asserts their stability for unit charge, as we also test in second-order perturbation theory.

  12. Disposable baby wipes: efficacy and skin mildness.

    Science.gov (United States)

    Odio, M; Streicher-Scott, J; Hansen, R C

    2001-04-01

    The results of a series of four clinical studies demonstrated that disposable baby wipes were milder to the skin than use of a cotton washcloth and water, recognized as a "gold standard" for skin mildness. Importantly, the baby wipes caused no significant change from the baseline value in any of the skin parameters examined. This observation verified that the test wipes are minimally disruptive to the epidermal barrier and thus suitable for use on intact or compromised, irritated skin.

  13. Resuscitating the Baby after Shoulder Dystocia

    OpenAIRE

    Menticoglou, Savas; Schneider, Carol

    2016-01-01

    Background. To propose hypovolemic shock as a possible explanation for the failure to resuscitate some babies after shoulder dystocia and to suggest a change in clinical practice. Case Presentation. Two cases are presented in which severe shoulder dystocia was resolved within five minutes. Both babies were born without a heartbeat. Despite standard resuscitation by expert neonatologists, no heartbeat was obtained until volume resuscitation was started, at 25 minutes in the first case and 11 m...

  14. Traditional foods vs. manufactured baby foods.

    Science.gov (United States)

    Ferguson, Elaine L; Darmon, Nicole

    2007-01-01

    The provision of nutrient-dense complementary foods is essential to ensure an infant's nutrient requirements are met. Yet often, relative to recommendations, traditional complementary foods have low levels of nutrients, suggesting a role, for fortified manufactured baby foods, in ensuring dietary adequacy. In this review, the potential benefits and safety of using fortified manufactured baby foods versus traditional foods alone are evaluated based on evidence from food composition data, diet modeling and intervention studies. Results from the food composition data and diet modeling suggest that ensuring a nutritionally adequate complementary feeding diet based on traditional foods alone is difficult. Conversely, except for biochemical iron status, intervention trials do not show consistent benefits, for growth or biochemical zinc or riboflavin status, with the use of fortified manufactured baby foods versus traditional foods alone. The safety of manufactured baby foods will depend on food preparation practices and the presence of effective governmental regulatory infrastructures. Hence, in environments where fortified manufactured baby foods are expensive, unavailable or where there is an absence of effective governmental regulatory infrastructures, the use of traditional foods is advised. Conversely, where affordable manufactured baby foods are available, marketed safely and fortified appropriately, their use is likely to result in improved nutrient intakes and infant biochemical iron status. In all environments, the promotion of breastfeeding, active feeding and high levels of hygiene is essential to ensure optimal nutritional status.

  15. Baby boom generation at the retirement onset

    Directory of Open Access Journals (Sweden)

    Stojilković Jelena

    2010-01-01

    Full Text Available Sudden increase in the number of live births after the Second World War due to an increase in fertility rates has led to the formation of cohorts with specific characteristics or baby boom generation. This generation is unique in the history of the demographic phenomenon that has affected and affects the functioning of many segments of society. The aim of this paper is to assess structure of baby boomers who are few years away from retirement, using demographic data. Impact of baby boomer age structure of current and future retirees is described with a graphical display of current and projected age pyramid of baby boomers. Demographic pattern that women live longer than men is evident in the projected pyramid. In addition, the number of baby boomers will lead to a "younger" old population. The imbalance in the number of men and women pensioners, as well as older cohorts of women and female baby boomers was analyzed. As a result, an increasing trend of women's age pensioners who are members of the baby boom generation was clearly observed, which is opposite to the older cohort of women who often were family pensioners. Different circumstances and conditions in which female boomers lived and worked will form a new "pension model" because they will gain their benefits as well as men, for the first time in significant number, unlike their mothers, which gained the right to retire after they become widows. Number of women age pensioners is getting greater comparing to men, as the result of changes in the economic activities of women in the last half of the 20th century. When baby boomers retire and exit the working population, this will create a vacuum, because the numerically smaller generations will enter working population, while the sudden and very shortly, the number of population older than 60 or 65 will increase, most of them will likely to acquire the right to a pension. It is undeniable that baby boomers had impact on demographic structure

  16. Secondhand smoke induces hepatic apoptosis and fibrosis in hamster fetus.

    Science.gov (United States)

    Huang, Chien-Wei; Horng, Chi-Ting; Huang, Chih-Yang; Cho, Ta-Hsiung; Tsai, Yi-Chang; Chen, Li-Jeng; Hsu, Tsai-Ching; Tzang, Bor-Show

    2016-09-01

    Secondhand smoke (SHS) is an important health issue worldwide. Inhaling SHS during pregnancy could cause abnormalities in the internal tissues of newborns, which may then impair fetal development and even cause severe intrauterine damage and perinatal death. However, the understanding of cytopathic mechanisms of SHS by maternal passive smoking on fetus liver during pregnancy is still limited. This study analyzed the effects of high-dose SHS (SHSH) on fetus liver using a maternal passive smoking animal model. Experiments showed that hepatic matrix metalloproteinase-9 activity and terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling-positive cells were significantly increased in livers from fetuses of hamsters treated with SHSH. Similarly, expressions of both extrinsic and intrinsic apoptotic molecules were significantly higher in livers from fetuses of hamsters exposed to SHSH. Additionally, significantly increased inflammatory proteins, including transforming growth factor β, inducible nitric oxide synthase, and interleukin 1β, and fibrotic signaling molecules, including phosphorylated Smad2/3, SP1, and α-smooth muscle actin, were observed in the fetus livers from hamsters treated with SHSH. This study revealed that SHSH not only increased apoptosis through intrinsic and extrinsic pathways in the livers of fetuses from hamsters exposed to SHSH but also augmented hepatic fibrosis via Smad2/3 signaling. © The Author(s) 2015.

  17. Proliferation of epithelial cell forming hamster palate during prenatal period

    Czech Academy of Sciences Publication Activity Database

    Buchtová, M.; Tichý, F.; Matulová, Petra; Míšek, Ivan

    2003-01-01

    Roč. 76, č. 4 (2003), s. 254-255 [Moravský morfologický den/4./. 11.06.2003, Brno] R&D Projects: GA ČR GA304/02/0448; GA ČR GP304/01/P021 Institutional research plan: CEZ:AV0Z5045916 Keywords : hamster Subject RIV: ED - Physiology

  18. Het effect van hamsterbeheer op de overwintering bij hamsters

    NARCIS (Netherlands)

    Beek, van der M.; Ligtenberg, H.; Haye, la M.J.J.

    2006-01-01

    De afgelopen decennia is het aantal hamsters (Cricetus cricetus) in Nederland sterk afgenomen. Door onderzoek te verrichten naar de levenscyclus en naar de effecten van agrarisch beheer is getracht de afname te verklaren en oplossingen aan te dragen. In voorjaar 2006 is een verkennend onderzoek

  19. Humanizing recombinant glycoproteins from Chinese hamster ovary cells

    DEFF Research Database (Denmark)

    Hansen, Anders Holmgaard; Amann, Thomas; Kol, Stefan

    hamster ovary (CHO) cells are making a very heterogeneous mixture of NGlycans. We speculate that the CHO pattern of N-Glycans would affect half-life and/or efficacy of the glycoprotein in the bloodstream making it unsuitable for human intravenous use, whereas our humanized version would be identical...

  20. Enhanced longevity in tau mutant Syrian hamsters, Mesocricetus auratus

    NARCIS (Netherlands)

    Oklejewicz, Malgorzata; Daan, Serge

    The single-gene mutation tau in the Syrian hamster shortens the circadian period by about 20% in the homozygous mutant and simultaneously increases the mass-specific metabolic rate by about 20%. Both effects might be expected to lead to a change in longevity. To test such expectations, the life span

  1. Bioavailability and disposition of solanine in rats and hamsters

    NARCIS (Netherlands)

    Groen K; Pereboom-de Fauw DPKH; Besamusca P; Beekhof PK; Speijers GJA; Derks HJGM

    1992-01-01

    The toxicokinetics of [3H]-alpha-solanine after oral (po) and intravenous (iv) administration in rats and hamsters were studied, in order to decide which is the most appropriate model in risk assessment studies. The iv dose was 54 mug/kg; the oral dose was 170 mug/kg. After iv administration, the

  2. Development of Taenia pisiformis in golden hamster (Mesocricetus auratus

    Directory of Open Access Journals (Sweden)

    Maravilla Pablo

    2011-07-01

    Full Text Available Abstract The life cycle of Taenia pisiformis includes canines as definitive hosts and rabbits as intermediate hosts. Golden hamster (Mesocricetus auratus is a rodent that has been successfully used as experimental model of Taenia solium taeniosis. In the present study we describe the course of T. pisiformis infection in experimentally infected golden hamsters. Ten females, treated with methyl-prednisolone acetate were infected with three T. pisiformis cysticerci each one excised from one rabbit. Proglottids released in faeces and adults recovered during necropsy showed that all animals were infected. Eggs obtained from the hamsters' tapeworms, were assessed for viability using trypan blue or propidium iodide stains. Afterwards, some rabbits were inoculated with eggs, necropsy was performed after seven weeks and viable cysticerci were obtained. Our results demonstrate that the experimental model of adult Taenia pisiformis in golden hamster can replace the use of canines in order to study this parasite and to provide eggs and adult tapeworms to be used in different types of experiments.

  3. Early postnatal development of the South African hamster ...

    African Journals Online (AJOL)

    The South African Hamster Mystromys albicaudatus has been bred in the laboratory of the. Medical Ecology Centre since 1941. It is of interest taxonomically in that it is the sole repre- sentative left in Africa of the subfamily Cricetinae (Davis 1962). It has been used in Medical. Research on poliomyelitis, benign ...

  4. Early Postnatal Development of the South African Hamster ...

    African Journals Online (AJOL)

    The South African Hamster Mystromys albicaudatus has been bred in the laboratory of the Medical Ecology Centre since 1941. It is of interest taxonomically in that it is the sole representative left in Africa of the subfamily Cricetinae (Davis 1962). It has been used in Medical Research on poliomyelitis, benign histoplasmosis, ...

  5. Breech Babies: What Can I Do If My Baby Is Breech?

    Science.gov (United States)

    ... and protects the baby. An abnormal fetal heart Premature rupture of the membranes. Twins or other multiples pregnancy. ECV usually is ... ECV are small, but include: Early onset labor. Premature rupture of the membranes. Minor blood loss for either the baby or ...

  6. What is my Baby Like? Representations Concerning the Baby in the Third Trimester of Pregnancy

    Directory of Open Access Journals (Sweden)

    Marta Pedreira

    2015-11-01

    Full Text Available AimTo investigate if during the third trimester of pregnancy fantasies emerge in the baby representations based on the information that pregnant women have on their real babies through ultrasound techniques.MethodA qualitative, descriptive and exploratory research based on a sample of 30 pregnant Portuguese women, whose average age is 32 years old, was developed. A socio-demographic questionnaire and a semi-directive interview entitled "Interview of Maternal Representations During Pregnancy – Revised Version" (IRMAG-R, Ammaniti & Tambelli, 2010 were employed.ResultsBaby representations are immersed in a fantasy dimension, which means that the imaginary baby is quite present in this phase of pregnancy. Pregnant women mainly attribute psychological characteristics to the babies, rather than physical characteristics. Regardless of the type of characteristics analysed, the preference for these characteristics emerges based on their wishes. Secondly, characteristics of the parents may also emerge. Fetal movements and information from ultrasound have no significant influence on the characterization of the baby.ConclusionDespite the development of ultrasound techniques, the imaginary baby defines parents representations about the baby on the third trimester of pregnancy. Consequently, a new understanding of how pregnant women experience the transition to the postnatal phase has to be considered.

  7. Seasonal aspects of sleep in the Djungarian hamster

    Directory of Open Access Journals (Sweden)

    Deboer Tom

    2003-05-01

    Full Text Available Abstract Background Changes in photoperiod and ambient temperature trigger seasonal adaptations in the physiology and behaviour of many species, including the Djungarian hamster. Exposure of the hamsters to a short photoperiod and low ambient temperature leads to a reduction of the polyphasic distribution of sleep and waking over the light and dark period. In contrast, a long photoperiod enhances the daily sleep-wake amplitude leading to a decline of slow-wave activity in NREM sleep within the light period. It is unknown whether these changes can be attributed specifically to photoperiod and/or ambient temperature, or whether endogenous components are contributing factors. The influence of endogenous factors was investigated by recording sleep in Djungarian hamsters invariably maintained at a low ambient temperature and fully adapted to a short photoperiod. The second recording was performed when they had returned to summer physiology, despite the maintenance of the 'winter' conditions. Results Clear winter-summer differences were seen in sleep distribution, while total sleep time was unchanged. A significantly higher light-dark cycle modulation in NREM sleep, REM sleep and waking was observed in hamsters in the summer physiological state compared to those in the winter state. Moreover, only in summer, REM sleep episodes were longer and waking bouts were shorter during the light period compared to the dark period. EEG power in the slow-wave range (0.75–4.0 Hz in both NREM sleep and REM sleep was higher in animals in the summer physiological state than in those in the 'winter' state. In winter SWA in NREM sleep was evenly distributed over the 24 h, while in summer it decreased during the light period and increased during the dark period. Conclusion Endogenous changes in the organism underlie the differences in sleep-wake redistribution we have observed previously in hamsters recorded in a short and long photoperiod.

  8. Modeling the dual pacemaker system of the tau mutant hamster.

    Science.gov (United States)

    Oda, G A; Menaker, M; Friesen, W O

    2000-06-01

    Circadian pacemakers in many animals are compound. In rodents, a two-oscillator model of the pacemaker composed of an evening (E) and a morning (M) oscillator has been proposed based on the phenomenon of "splitting" and bimodal activity peaks. The authors describe computer simulations of the pacemaker in tau mutant hamsters viewed as a system of mutually coupled E and M oscillators. These mutant animals exhibit normal type 1 PRCs when released into DD but make a transition to a type 0 PRC when held for many weeks in DD. The two-oscillator model describes particularly well some recent behavioral experiments on these hamsters. The authors sought to determine the relationships between oscillator amplitude, period, PRC, and activity duration through computer simulations. Two complementary approaches proved useful for analyzing weakly coupled oscillator systems. The authors adopted a "distinct oscillators" view when considering the component E and M oscillators and a "system" view when considering the system as a whole. For strongly coupled systems, only the system view is appropriate. The simulations lead the authors to two primary conjectures: (1) the total amplitude of the pacemaker system in tau mutant hamsters is less than in the wild-type animals, and (2) the coupling between the unit E and M oscillators is weakened during continuous exposure of hamsters to DD. As coupling strength decreases, activity duration (alpha) increases due to a greater phase difference between E and M. At the same time, the total amplitude of the system decreases, causing an increase in observable PRC amplitudes. Reduced coupling also increases the relative autonomy of the unit oscillators. The relatively autonomous phase shifts of E and M oscillators can account for both immediate compression and expansion of activity bands in tau mutant and wild-type hamsters subjected to light pulses.

  9. Baby factories taint surrogacy in Nigeria.

    Science.gov (United States)

    Makinde, Olusesan Ayodeji; Makinde, Olufunmbi Olukemi; Olaleye, Olalekan; Brown, Brandon; Odimegwu, Clifford O

    2016-01-01

    The practice of reproductive medicine in Nigeria is facing new challenges with the proliferation of 'baby factories'. Baby factories are buildings, hospitals or orphanages that have been converted into places for young girls and women to give birth to children for sale on the black market, often to infertile couples, or into trafficking rings. This practice illegally provides outcomes (children) similar to surrogacy. While surrogacy has not been well accepted in this environment, the proliferation of baby factories further threatens its acceptance. The involvement of medical and allied health workers in the operation of baby factories raises ethical concerns. The lack of a properly defined legal framework and code of practice for surrogacy makes it difficult to prosecute baby factory owners, especially when they are health workers claiming to be providing services to clients. In this environment, surrogacy and other assisted reproductive techniques urgently require regulation in order to define when ethico-legal lines have been crossed in providing surrogacy or surrogacy-like services. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  10. Phthalates in baby skin care products.

    Science.gov (United States)

    Lampel, Heather P; Jacob, Sharon E

    2011-01-01

    The systemic toxicity of phthalates has been extensively reported. Although rarely sensitizing, phthalates have been implicated in promoting the development of both atopy and contact dermatitis in animal models. Dermal absorption of phthalates may contribute to overall chemical burden. Infants may be particularly susceptible to chemical exposures. Baby skin care products may be a significant source of phthalate exposure. We measured the phthalate content of 30 skin care products intended for babies and children. Nineteen leave-on and 11 wash-off baby skin care products were analyzed for 17 unique phthalates by an independent laboratory using standard gas chromatographic mass spectrometry. Of 30 products tested, four had phthalate levels above the reporting limit (0.1-0.5 ppm); of these, only one had levels above 1 ppm (44 ppm). There was no statistical significance of phthalate detection in leave-on versus wash-off products (p = .578). The majority (26 of 30) of the baby skin care products analyzed did not have detectable phthalate levels. Four products had detectable phthalate levels. In baby skin care products, levels of the 17 phthalates tested are low overall, but occasional products may contain higher phthalate levels. Monitoring products to ensure safety standards are met may be warranted.

  11. Reducing the risk of baby falls in maternity units.

    Science.gov (United States)

    Janiszewski, Helen

    During a 12-month period there were 17 baby falls on the maternity wards at Nottingham University Hospitals Trust; two of the babies who fell were injured. By collecting information about the baby falls and how they happened, we were able to compile a guideline for both preventing and managing baby falls. This formed part of the trust's patient safety programme. We then piloted and implemented risk-prevention strategies for baby falls. These involved a risk assessment to identify women needing closer observation and the installation of bedside cots. These strategies brought about a marked reduction of baby falls and are now being established across all the maternity units across the trust.

  12. Mothers' use of and attitudes to BabyCheck.

    OpenAIRE

    Thomson, Hilary; Ross, Sue; Wilson, Philip; McConnachie, Alex; Watson, Richard

    2002-01-01

    A copy of BabyCheck was sent to 497 mothers shortly after the birth of their baby. Six months later they were sent a questionnaire asking about their use of and attitudes to, BabyCheck. Questionnaires were returned by 323 (65%) mothers; 215 (67%) of them reported reading BabyCheck, the majority found it easy to understand (74%) and agreed with the advice (67%). Eighty-four (26%) of the mothers who returned the questionnaires reported using BabyCheck when their baby was ill; of these, 71% agre...

  13. Helping Babies Breathe implementation in Zanzibar, Tanzania.

    Science.gov (United States)

    Wilson, Gina Marie; Ame, Ame Masemo; Khatib, Maimuna Mohamed; Rende, Elizabeth K; Hartman, Ann Michelle; Blood-Siegfried, Jane

    2017-08-01

    To assess the efficacy and feasibility of implementing Helping Babies Breathe, a neonatal resuscitation programme for resource-limited environments. This quality improvement project focused on training midwives on Helping Babies Breathe to address high rates of neonatal mortality secondary to birth asphyxia. The convenience sample was 33 midwives in Zanzibar, Tanzania. The train-the-trainer strategy with repeated measures design was used to assess knowledge and skills at 3 time points. Observations were completed during "real-time" deliveries, and a focused interview generated feedback regarding satisfaction and sustainability. Knowledge scores and resuscitation skills significantly improved and were sustained, P < .05. Of the 62 birth observations, 19% needed intervention. All were appropriately resuscitated and survived. Results indicate that participants retained knowledge and skills and used them in clinical practice. Observations demonstrated that participants took appropriate actions when presented with a baby who was not breathing. © 2017 John Wiley & Sons Australia, Ltd.

  14. VTR module: weaning foods for baby.

    Science.gov (United States)

    1993-01-01

    Weaning should start when the baby turns 4 months old. At this stage (4 to 6 months), milk is no longer enough. Parents should introduce new foods which can meet the fast-increasing nutrition needs of the child. Among the latest materials produced by the Video Radio Production Division of the Nutrition Center of the Philippines is a VTR training module entitled "Karagdagang Pagkain ni Baby" (Weaning Foods for Baby), designed to strengthen this important aspect of child care. Specifically, the module seeks to encourage parents to introduce foods in addition to breastmilk to their 4 to 6 month old children and to start giving them "complete" meals from 6 months onward. It provides suggestions on the kinds of foods or food combinations to give to the baby and encourages home food production (backyard gardening, poultry-raising etc) to supply food requirements of growing children. Contents of the module include how-to's on weaning food preparation (mashing, straining, flaking, chopping, scraping, etc), prescriptions on the kinds and amounts of foods for babies; and food combinations (porridge or rice and a viand from the 3 basic food groups: energy-giving, body building and regulating). For instance, at 4 months old, the baby may be given lugao (porridge), soup and fruits; at 5 months, eggs, vegetables and beans; at 6 months, fish/meat, oil or gata (coconut oil). With a running time of 18 minutes, the module uses computer graphics to highlight food items, recommended amounts, and age group requirements in the text, and applies digital multi-effects to ensure smooth traditions. full text

  15. Medullary Sponge Kidney

    Science.gov (United States)

    ... tubes, inside a fetus’ kidneys. In a normal kidney , urine flows through these tubules as the kidney is being formed during a ... not fully understand the cause of medullary sponge kidney or why cysts form in the tubules during fetal development. Even though medullary sponge kidney ...

  16. Should babies be watching television and DVDs?

    Science.gov (United States)

    Wartella, Ellen A; Lauricella, Alexis R

    2012-06-01

    Should babies be watching television and DVDs? This is a reasonable question to ask but a difficult one to answer. This article reviews the theories and related research to examine what is known about infant media use. The review provides evidence both for and against each theory. The importance of infants learning how to watch and learn from screen media presentations is indicated and the new world of media to which babies are exposed is discussed. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Sensibility of the hamster (Cricetus auratus to the Treponema pertenue

    Directory of Open Access Journals (Sweden)

    F. Nery-Guimarães

    1955-05-01

    Full Text Available In two experiments, 8 Hamsters inoculated with material from yaws lesions (Treponema pertenue, developed skin lesions considered specific by their clinical and histopathological aspects and by the presence of treponemae. These lesions appeared on the scrotumm, testicle, prepuce, anus, tail, muzzle, back and hinders paws (palm surface. In the internal organs no treponemae were found in direct examinations and inoculation of brain, spleen and lymph node. The incubation period was of 35 days for the testicle, 55 days for the scrotum and 107 days for peritoneal cavity inoculation. Positive sub-inoculations were obtained. The serum reactions (Qasserman's and Kahn's were negative in all 5 tested Hamsters. Out of 4 normal females matched to infected males two developed nasal lesions resulting from direct contact. Apparently the genital lesions hindered copulation. Hamsters are very well suited for an experimental study of yaws.Em 2 experiências, 8 Hamsters inoculados com material direto de lesões boubáticas (Treponema pertenue, desenvolveram lesões cutâneas consideradas específicas, pelo aspecto clínico e histopatológico e pela presentça de treponemas. Essas lesões se manifestaram no escrôto, testículo, prepúcio, anus, cauda, focinho, dorso e patas posteriores (face palmar. Nos órgãos internos não foram vistos treponemas ao exame direto e, uma vez, por inoculação de cérebro, baço e gânglio linfático. O período incubativo foi de 35 dias pela via testicular, 55 dias pela via escrotal e 107 dias pela via peritonial. Foram obtidas sub-inoculações positivas para Hamsters normais. As experiências continuam. De 4 fêmeas normais, acasaladas com 4 hamsters infectados apenas 2 mostraram lesões positivas resultantes de contágio direto. Aparentemente, não houve copulação e, se esta ocorreu, não determinou fecundação.

  18. KIDNEY ANOMALIES: HORSE SHOE KIDNEY

    Directory of Open Access Journals (Sweden)

    Hemalatha

    2015-03-01

    Full Text Available INTRODUCTION : Horse Shoe Kidney was first recognized during an autopsy by De Carpi in 1521. This anomaly consists of two distinct renal masses lying vertically on either side of the midline and connected at their respective lower poles by a parenchymatous or fibrous isthmus that crosses the mid pl ane of the body. This isthmus lies at the level of 4th lumbar vertebra just beneath the origin of inferior mesenteric artery in about 40% of cases. Fusion of upper poles instead of the lower poles results in a n inverted horse Shoe Kidney which constitute 5 - 10% of ail Horse - Shoe kidneys , (i.e. in 95% of HSK , fusion is at lower poles. HSK is found more commonly in males by a 2 : 1 margin. AIM OF STUDY : An attempt has been made to know the various anomalies . The study has been taken up with the fond hope of helping the clinician , sonologist , and surgeons during their routine work. To apply this knowledge to the incoming post graduates in their research works. EMBRIOLOGICAL BASIS & KDNEY : The abnormality originates between 4th and 6th weeks of gestation , after the ureteral bud has entered the renal blastema. Boyden (1931 postulated that at the 14mm stage (4.5 weeks the developing metanephric masses lie close to one another , any disturbance in their relationship may result in joining at their inferior poles. A slight alteration in the position of the umbilical or common iliac artery could change the orientation of migrating kidneys thus leading to contact and fusion. In 1941 Dees (Nation 1945 , Bell 1946 , Gleen 1959 , Campbell 1970 described horse - shoe kidney di sease occurrence in 0.25% of the population or about 1 in 400. OBSERVATION : In the present study 176 specimens of kidneys were studied out of which 40 were fetal specimens and the rest were adult specimens consisting of both cadaveric and sonograms. The ad ult specimens from cadavers were 76 and 60 from sonograms. MATERIAL & METHODS : Abdomen is opened ; superficial viscera and

  19. Prenatal Development: How Your Baby Grows During Pregnancy

    Science.gov (United States)

    ... Management Education & Events Advocacy For Patients About ACOG Prenatal Development: How Your Baby Grows During Pregnancy Home ... Grows During Pregnancy FAQ156, June 2015 PDF Format Prenatal Development: How Your Baby Grows During Pregnancy Pregnancy ...

  20. Smaller kidney size at birth in South Asians: findings from the Born in Bradford birth cohort study.

    Science.gov (United States)

    Roderick, Paul J; Jeffrey, Robin F; Yuen, Ho M; Godfrey, Keith M; West, Jane; Wright, John

    2016-03-01

    Rates of advanced chronic kidney disease and renal replacement therapy are higher in South Asian than in white British populations. Low birth weight is also more frequent in South Asian populations and has been associated with increased risks of kidney disease, perhaps due to a reduced nephron endowment. Using ultrasound scans at 34 weeks of gestation, we measured fetal kidney dimensions (transverse and anteroposterior diameters, length and circumference) and derived volume in a random sample of 872 white British and 715 South Asian participants in the Born in Bradford cohort study. Kidney measurements were compared between ethnic groups. Birth weight for gestational age at 40 weeks was 200 g less in South Asian babies compared with white British babies. The mean kidney volume for gestational age was 16% lower in South Asian than in white British babies [8.79 versus 10.45 cm(3), difference 1.66 cm(3) (95% confidence interval 1.40-1.93, P < 0.001)]. The difference was robust after adjustment for maternal age, socio-economic factors, marital status, body mass index, smoking and alcohol use in pregnancy, parity, baby's gender and birth weight for gestational age [adjusted difference 1.38 cm(3) (0.97-1.84), P < 0.001]. There were smaller reductions in other fetal measures. South Asian babies have smaller kidneys compared with white British babies, even after adjusting for potential confounders including birth weight. This finding may contribute to increased risks of adult kidney disease in South Asian populations. © The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

  1. Acute kidney failure

    Science.gov (United States)

    Kidney failure; Renal failure; Renal failure - acute; ARF; Kidney injury - acute ... Symptoms of acute kidney failure may include any of the following: Bloody stools Breath odor and metallic taste in the mouth Bruising easily Changes in ...

  2. Kidney Replacement Therapy

    Science.gov (United States)

    ... Size: A A A Listen En Español Kidney Replacement Therapy Diabetes sometimes damages kidneys so badly that ... Dialysis Dialysis, the more common form of kidney-replacement therapy, is a way of cleaning the blood ...

  3. Chronic Kidney Disease (CKD)

    Science.gov (United States)

    ... Immunosuppressant medicines Anxiety, depression and mental health Kidney rejection Lifestyle changes Donate a kidney Being a living ... Healthy kidneys take the waste out of your blood. One type of waste is called creatinine. If you have ...

  4. Chronic Kidney Disease

    Science.gov (United States)

    ... control blood pressure, and make hormones. Chronic kidney disease (CKD) means that your kidneys are damaged and ... don't have any symptoms until their kidney disease is very advanced. Blood and urine tests are ...

  5. Kidney-Pancreas Transplant

    Science.gov (United States)

    ... Menu Menu Search Home Prevention Kidney Disease Patients Organ Donation & Transplantation Professionals Events Advocacy Donate A to Z Health ... Tests for Transplant Care After Kidney Transplant Common Organ Donation and Transplantation Terms The National Kidney Foundation (NKF) is the ...

  6. Testing for Kidney Disease

    Science.gov (United States)

    ... hypertension artérielle Heart Disease Mineral & Bone Disorder Chronic Kidney Disease Tests & Diagnosis How can I tell if I have kidney disease? Early kidney disease usually doesn’t have any ...

  7. Hamsters' (Mesocricetus auratus) memory in a radial maze analog: the role of spatial versus olfactory cues.

    Science.gov (United States)

    Tonneau, François; Cabrera, Felipe; Corujo, Alejandro

    2012-02-01

    The golden hamster's (Mesocricetus auratus) performance on radial maze tasks has not been studied a lot. Here we report the results of a spatial memory task that involved eight food stations equidistant from the center of a circular platform. Each of six male hamsters depleted the food stations along successive choices. After each choice and a 5-s retention delay, the hamster was brought back to the center of the platform for the next choice opportunity. When only one baited station was left, the platform was rotated to evaluate whether olfactory traces guided hamsters' choices. Results showed that despite the retention delay hamsters performed above chance in searching for food. The choice distributions observed during the rotation probes were consistent with spatial memory and could be explained without assuming guidance by olfactory cues. The radial maze analog we devised could be useful in furthering the study of spatial memory in hamsters.

  8. Baby Boom, Asset Market Meltdown and Liquidity Trap

    OpenAIRE

    Junning Cai

    2004-01-01

    A so-called “asset market meltdown hypothesis” predicts that baby boomers’ large savings will drive asset market booms that will eventually collapse because of the boomers’ large retirement dissavings. As good news to baby boomers, our analysis shows that this meltdown hypothesis is fundamentally flawed; and baby-boom-driven asset market booms may not necessarily collapse. However, bad news is that, in the case where meltdowns are about to happen, forward-looking baby boomers’ attempts to esc...

  9. Should we maintain baby hatches in our society?

    OpenAIRE

    Asai, Atsushi; Ishimoto, Hiroko

    2013-01-01

    Abstract Background A baby hatch called the “Stork’s Cradle” has been in place at Jikei Hospital in Kumamoto City, Japan, since May 10, 2007. Babyklappes were first established in Germany in 2000, and there are currently more than 90 locations. Attitudes regarding baby hatches are divided in Japan and neither opinions for nor against baby hatches have thus far been overwhelming. To consider the appropriateness of baby hatches, we present and examine the validity of each major objection to est...

  10. Baby Cry Detection in Domestic Environment using Deep Learning

    OpenAIRE

    Ijzerman, Hans

    2017-01-01

    Automatic detection of a baby cry in audio signals is an essential step in applications such as remote baby monitoring. It is also important for researchers, who study the relation between baby cry patterns and various health or developmental parameters. In this paper, we propose two machine-learning algorithms for automatic detection of baby cry in audio recordings. The first algorithm is a low-complexity logistic regression classifier, used as a reference. To train this classifier, we extra...

  11. Rapid induction of glomerular lipidosis in APA hamsters by streptozotocin.

    Science.gov (United States)

    Han, J. S.; Sugawara, Y.; Doi, K.

    1992-01-01

    The pathology of male Syrian hamsters of APA strain which were injected intraperitoneally with 40 mg/kg body weight of streptozotocin (SZ) at 2 months of age was examined. It showed long-lasting prominent hyperglycaemia and hyperlipidaemia with glucosuria and the development of glomerular lipidosis from 1 month after SZ-injection (1 MAI). Glomerular lesions were restricted to the juxtamedullary cortex at 1 MAI and then extended to the subcapsular cortex. At 3 MAI, glomerular lesions were characterized by focal segmental glomerulosclerosis showing segmental expansion of the mesangial area due to an increase of basement membrane-like material and mesangial cells with lipid droplets and foam cells. SZ-induced diabetic APA hamsters will be a useful model for the investigation of glomerular lipidosis and focal segmental glomerulosclerosis. Images Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 PMID:1533531

  12. Cystolithiasis in a Syrian hamster: a different outcome

    Directory of Open Access Journals (Sweden)

    D. Petrini

    2016-08-01

    Full Text Available A 14-month-old intact male Syrian hamster was admitted for lethargy and hematuria. A total body radiographic image and abdominal ultrasonography showed the presence of a vesical calculus. During cystotomy, a sterile urine sample was obtained and sent to the diagnostic laboratory along with the urolith for analysis. Urine culture was found negative for bacterial growth, and the urolith was identified as a calcium-oxalate stone. Diet supplementation with palmitoylethanolamide, glucosamine and hesperidin was adopted the day after discharge. One year follow up revealed no presence of vesical calculi. Although this is the report of a single clinical case, this outcome differs from the results reported in the literature characterized by recurrences after few months. Considering the positive outcome and the beneficial properties of palmitoylethanolamide, glucosamine, and hesperidin, these nutritional elements in Syrian hamsters, are recommended to reduce recurrence after surgical treatment of urolithiasis.

  13. [Investigation on the prevalence of gastrointestinal parasites in pet hamsters].

    Science.gov (United States)

    Lv, Chao-Chao; Feng, Chao; Qi, Meng; Yang, Hong-Yu; Jian, Fu-Chun; Ning, Chang-Shen; Zhang, Long-Xian

    2009-06-01

    One hundred and fifty-three fecal samples of pet hamsters (Mesocricetus auratus, Phodopus sungorus, P. campbelli and P. roborovskii) were collected from a pet-market in Zhengzhou, and examined by Sheather's sugar flotation, modified acid-fast staining and Lugol's iodine-solution staining. The prevalence of parasites was 70.7% (41/58), 96.7% (59/61), 83.9% (26/31), and 100% (3/3) respectively, with an overall prevalence of 84.3%. Eggs, cysts or oocysts of Cryptosporidium sp. (15.0%), Giardia sp. (22.2%), coccidian (2.0%), Hymenolepis nana (31.4%), Hymenolepis diminuta (25.5%), Syphacia spp. (41.8%), Aspiculuris tetraptera (7.2%) and undetermined Trichurata nematode (18.3%) were found from the samples. The results suggest that pet hamsters may be infected and transmit several zoonotic parasites.

  14. Cadmium and the kidney.

    OpenAIRE

    Friberg, L

    1984-01-01

    The paper is a review of certain aspects of importance of cadmium and the kidney regarding the assessment of risks and understanding of mechanisms of action. The review discusses the following topics: history and etiology of cadmium-induced kidney dysfunction and related disorders; cadmium metabolism, metallothionein and kidney dysfunction; cadmium in urine as indicator of body burden, exposure and kidney dysfunction; cadmium levels in kidney and liver as indicators of kidney dysfunction; cha...

  15. Expedient Treatment of a Collodion Baby

    Directory of Open Access Journals (Sweden)

    Michael Chung

    2011-01-01

    Full Text Available Only ~270 cases of collodion babies have been reported in the literature since 1892. As the name suggests, the term “collodion baby” refers to a phenotype that can be characterized by a yellow, shiny, tight parchment-like membrane stretched over the skin. Although the collodion membrane is only an evanescent condition of the newborn, neonatal complications can occur in 45% of all collodion babies, leading to a mortality rate of ~11% in the first few weeks of life. Most children born as collodion babies will spontaneously desquamate within 2 weeks, but may be as long as 3 months. Eventually, these children develop signs of one of several types of ichthyosis, which gives the skin the appearance of “fish scales.” We report a unique case of a Caucasian male that was born as a Collodion baby at the University of Kentucky Children's Hospital in Lexington, Kentucky. Although the impairment of the skin barrier function put the patient at risk for a number of complications, he improved significantly after being treated with emollients and antibiotics. In contrast to previous findings, we found that skin emollients were beneficial and did not increase the risk of infection.

  16. Baby Bell Libraries?--An Update.

    Science.gov (United States)

    Kessler, Jack

    1993-01-01

    Discusses the emerging three-tiered structure (i.e., the "Baby Bells," network nodes, and information marketers) that will assume responsibility for implementing a new national information network and getting networked information to the public. The role of libraries related to networked information is also considered. (EA)

  17. Completion Agenda for Baby Boomers. Commentary

    Science.gov (United States)

    Fishman, Seth

    2011-01-01

    In the article, "Completion Agenda for Baby Boomers", Moltz highlights how community colleges are currently implementing programs, such as the American Association of Community Colleges' Plus 50 Completion strategy, to encourage older learners to return to America's college campuses. The effects of the recent recession and the…

  18. Babies Bottom Out--A 'Maybe Boom'

    Science.gov (United States)

    Science News, 1977

    1977-01-01

    Data for the period September 1976 through April 1977 indicate a rise in the United States birth rate; however, the rate is still below the replacement level. It is speculated that the increase is an "echo" effect to the post-World War II baby boom which peaked in 1957. (SL)

  19. How to Care for Your Baby's Teeth

    Science.gov (United States)

    ... in them. You can give your baby a pacifier but only when needed. Try to stop using a pacifier around age 2. The same age applies for ... who suck their thumbs. Prolonged use of a pacifier or thumb sucking can cause problems with teeth ...

  20. Social Early Stimulation of Trisomy-21 Babies

    Science.gov (United States)

    Aparicio, Maria Teresa Sanz; Balana, Javier Menendez

    2003-01-01

    This study was initiated with twenty Down's syndrome babies to verify whether subjects undergoing social early stimulation would benefit from this type of treatment. An experimental study was designed with two training groups: visual or written instructions. The analyses of the results established statistically significant differences in the…

  1. Faith, existence and birth of preterm babies

    DEFF Research Database (Denmark)

    Rasmussen, Christina Prinds

    The aim is to explore if becoming a mother preterm of a premature baby, actualises existential and religious issues, and to explore the impact of the considerations in their way of coping. It is thus to shed light on these issues, that can both function as a positive coping-resource and the oppos...

  2. Baby massage: a dialogue of touch.

    Science.gov (United States)

    Bond, Cherry

    2002-01-01

    The significance and benefits of touch and massage for preterm infants in Neonatal Intensive Care Units and in the community are discussed. The article emphasises the value of massage in helping parents to bond with their baby and as part of family-centred care. A bibliography is included.

  3. Me? Have a Baby? Preconception Health

    Centers for Disease Control (CDC) Podcasts

    2012-10-01

    Preconception health means taking care of your own health now so you’ll be healthy for yourself and your future baby.  Created: 10/1/2012 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 10/1/2012.

  4. Me? Have Another Baby? Preconception Health

    Centers for Disease Control (CDC) Podcasts

    2012-10-01

    Preconception health means taking care of your own health now so you’ll be healthy for yourself and your future baby.  Created: 10/1/2012 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 10/1/2012.

  5. The baby has not come: obstructed labour

    African Journals Online (AJOL)

    Introduction. This article is about how to recognize obstructed labour and deal with it in a way that preserves the life and health of mother and child. It is for midwives and others who work in maternity care and is based on our experiences in Yei, South Sudan. Obstructed labour means that the baby is too big to pass through ...

  6. Radioprotective effect of catecholamines on the cultured Chinese hamster fibroblasts

    International Nuclear Information System (INIS)

    Chirkov, Yu.Yu.; Malatsidze, M.A.; Sobolev, A.S.

    1985-01-01

    On cultivated in vitro Chinese hamster fibroblasts radioprotective properties of adrenaline, noradrenaline and isoproterenol in different concentrations are studied. Isoproterenol radiopreventive effect is clearly manifested with its concentration being 1x10 -8 M; adrenaline and noradrenaline are efficient in higher concentrations. Propranolol, blocking β-adrenergic receptors, completely presents radioprotective effect of catecholamines on the cells. β-adrenergic mechanism of catecholamine radioprotective effect on Mammalia cells is discussed

  7. Autoradiographic images in the hamster cheek pouch oral cancer model

    International Nuclear Information System (INIS)

    Portu, A.; Molinari, A.J.; Schwint, A.; Saint Martin, G.; Thorp, S.; Pozzi, E.C.C.; Curotto, P.

    2013-01-01

    The aim of this work is to summarize the autoradiographic study performed to samples from different protocols of the hamster cheek pouch oral cancer model. The qualitative analysis of histological and autoradiographic images, together with the determination of the boron concentration in the different structures of tumor, premalignant tissue and normal tissue contributed to the knowledge of the microdistribution of boron compounds. Besides, the study led to the optimization of the autoradiography technique applied to BNCT (Boron Neutron Capture Therapy). (author)

  8. A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.

    Directory of Open Access Journals (Sweden)

    Mariana L Coutinho

    2011-12-01

    Full Text Available The leptospiral LigA protein consists of 13 bacterial immunoglobulin-like (Big domains and is the only purified recombinant subunit vaccine that has been demonstrated to protect against lethal challenge by a clinical isolate of Leptospira interrogans in the hamster model of leptospirosis. We determined the minimum number and location of LigA domains required for immunoprotection. Immunization with domains 11 and 12 was found to be required but insufficient for protection. Inclusion of a third domain, either 10 or 13, was required for 100% survival after intraperitoneal challenge with Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130. As in previous studies, survivors had renal colonization; here, we quantitated the leptospiral burden by qPCR to be 1.2×10(3 to 8×10(5 copies of leptospiral DNA per microgram of kidney DNA. Although renal histopathology in survivors revealed tubulointerstitial changes indicating an inflammatory response to the infection, blood chemistry analysis indicated that renal function was normal. These studies define the Big domains of LigA that account for its vaccine efficacy and highlight the need for additional strategies to achieve sterilizing immunity to protect the mammalian host from leptospiral infection and its consequences.

  9. Cross neutralizing antibodies in hamsters vaccinated with leptospiral bacterins produced with three serovars of serogroup Sejroe

    Directory of Open Access Journals (Sweden)

    Rosana Tabata

    2002-09-01

    Full Text Available Three leptospiral bacterins, produced with different serovars of Serogroup Sejroe, namely the hardjo (bacterin A, wolffi (bacterin B and guaricura (bacterin C, were evaluated in male hamsters (Mesocricetus auratus by comparing the agglutinating and neutralizing antibodies titers using microscopic agglutination (MAT and in vitro growth inhibition (GIT tests. The immunization schedule was based on two 1.0 mL doses of non-diluted formalininactivated whole culture bacterin given through subcutaneous route with 10-day interval. The challenge was performed ten days after the second vaccine dose, when the animals were inoculated with 0.2 mL of non-inactivated cultures of each serovar through intraperitoneal route. On the 21st post-challenge day (PCD, all animals were bled and their sera were joined in pools (n=8 and tested by MAT and GIT. All vaccinated and control animals presented no clinical signs of leptospirosis after the challenge, but the serovar guaricura was isolated from the kidneys of control animals on the 21st PCD. The MAT results showed cross agglutinins between serovars hardjo and wolffi, and between wolffi and guaricura. The GIT results revealed the presence of cross neutralizing antibodies between serovars wolffi or guaricura against hardjo, wolffi and guaricura. It was found that the tested strain of serovar hardjo did not produce detectable levels of neutralizing antibodies, indicating its poor immunogenicity.

  10. Why at Least 39 Weeks Is Best for Your Baby?

    Science.gov (United States)

    ... more health problems at birth and later in life than babies born later. Being pregnant 39 weeks gives your baby's body all the time it needs to grow. Here's why your baby needs 39 weeks: Important organs, like his brain, lungs and liver, get the time they need ...

  11. Kangaroo Mother Care Management of a 750 Ggrammes Baby: A ...

    African Journals Online (AJOL)

    This paper presents the successful management of 750 grammes low birth weight baby using kangaroo mother care in the hospital and at home. The baby had suffered a variety of morbidities associated with prematurity in the early neonatal period. Key words: Kangaroo mother care, low birth weight babies ...

  12. Your Baby's Hearing, Vision, and Other Senses: 11 Months

    Science.gov (United States)

    ... conversation Taste and Smell By this age, your baby is developing food preferences . Keep offering foods with a variety of ... can take 10 tries or more before a baby learns to like new food. Explore the sense of smell with your baby. ...

  13. Your Baby's Hearing, Vision, and Other Senses: 7 Months

    Science.gov (United States)

    ... a mobile over the crib or wall hangings within reach, remove them so your baby doesn't get hurt. Babies this age enjoy more complex patterns and color variations. Try reading books with large, brightly colored pictures to your baby, ...

  14. Risk factors for neonatal jaundice in babies presenting at the ...

    African Journals Online (AJOL)

    ... in this study was relatively high particularly in association with sepsis, prematurity and asphyxia. Mortality was higher in out-born babies than in in-born babies (p= 0.00). Conclusion: Early presentation of babies and adequate management of sepsis and prematurity will reduce mortality associated with neonatal jaundice.

  15. Infants & Toddlers: How Babies Use Gestures to Communicate

    Science.gov (United States)

    Honig, Alice Sterling

    2004-01-01

    Evolution has provided babies with wonderful ways to get the loving attention and care that they need from adults. When a baby is distressed, his cry is the most primitive and powerful tool for bringing help. By the time a baby is 2 or 3 months old, his dazzling smile and crooked grin evokes tenderness, smiles, and nurturance from adults who are…

  16. Equine herpesvirus type 1 induces both neurological and respiratory disease in Syrian hamsters.

    Science.gov (United States)

    Mesquita, Leonardo Pereira; Arévalo, Andressa Ferrari; Zanatto, Dennis A; Miyashiro, Samantha Ive; Cunha, Elenice Maria Sequetin; de Souza, Maria do Carmo Custódio; Villalobos, Eliana Monteforte Cassaro; Mori, Cláudia Madalena Cabrera; Maiorka, Paulo César; Mori, Enio

    2017-05-01

    The equine herpesvirus type 1 (EHV-1) is an important cause of myeloencephalopathy and respiratory disease in horses. Animal models for EHV-1 infection have been specially developed using mice and Syrian hamsters (Mesocricetus auratus). However, few studies have attempted to evaluate the pathogenesis of EHV-1 infection in the central nervous system (CNS) and respiratory system of hamsters. Therefore, the aim of this study was to evaluate the pathogenesis of four Brazilian EHV-1 strains within the CNS and lungs of Syrian hamsters. Hamsters intranasally infected with A4/72, A9/92, A3/97, and Iso/72 EHV-1 strains developed severe neurological and respiratory signs and died during acute EHV-1 infection within 3 to 5days post-inoculation. However, neurological signs were more severe in A4/72 and A9/92-infected hamsters, whereas respiratory signs were more prominent in A3/97 and Iso/72-infected hamsters. In the latter, lesions in the CNS were predominantly inflammatory, whereas in A4/72 and A9/92-infected hamsters, neuronal and liquefactive necrosis were the predominant lesions. EHV-1 infected hamsters also developed an interstitial pneumonia with infiltration of alveolar septa by macrophages, neutrophils, and lymphocytes, with the exception of A9/92-infected hamsters, which developed severe hemorrhages within the airways. EHV-1 antigens were detected along with CNS and pulmonary lesions. EHV-1 was also recovered from CNS of all infected hamsters, whereas the virus was recovered from the lungs of A4/72, A9/92, and Iso/72-infected hamsters. Brazilian EHV-1 strains caused both severe CNS and respiratory disease in hamsters, thus making this species an interesting model for EHV-1 infection in the CNS and respiratory system. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Hibernation, stress, intestinal functions, and catecholoamine turnover rate in hamsters and gerbils

    Science.gov (United States)

    Musacchia, X. J.

    1973-01-01

    Bioenergetic studies on hamsters during depressed metabolic states are reported. External support of blood glucose extended the survival times of hibernating animals. Radioresistance increased in hibernating as well as in hypothermic hamsters. Marked changes in hamster catecholamine turnover rates were observed during acclimatization to high temperature stress. High radioresistance levels of the gerbil gastrointestinal system were attributed in part to the ability of the gut to maintain functional integrity.

  18. Isolation of two chloroethylnitrosourea-sensitive Chinese hamster cell lines

    International Nuclear Information System (INIS)

    Hata, H.; Numata, M.; Tohda, H.; Yasui, A.; Oikawa, A.

    1991-01-01

    1-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-3-(2-chloroethyl)-3- nitrosourea hydrochloride (ACNU), a cancer chemotherapeutic bifunctional alkylating agent, causes chloroethylation of DNA and subsequent DNA strand cross-linking through an ethylene bridge. We isolated and characterized two ACNU-sensitive mutants from mutagenized Chinese hamster ovary cells and found them to be new drug-sensitive recessive Chinese hamster mutants. Both mutants were sensitive to various monofunctional alkylating agents in a way similar to that of the parental cell lines CHO9. One mutant (UVS1) was cross-sensitive to UV and complemented the UV sensitivity of all Chinese hamster cell lines of 7 established complementation groups. Since UV-induced unscheduled DNA synthesis was very low, a new locus related to excision repair is thought to be defective in this cell line. Another ACNU-sensitive mutant, CNU1, was slightly more sensitive to UV than the parent cell line. CNU1 was cross-sensitive to 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and slightly more sensitive to mitomycin C. No increased accumulation of ACNU and a low level of UV-induced unscheduled DNA synthesis in this cell as compared with the parental cell line suggest that there is abnormality in a repair response of this mutant cell to some types of DNA cross-links

  19. Female-biased anorexia and anxiety in the Syrian hamster.

    Science.gov (United States)

    Shannonhouse, John L; Fong, Li An; Clossen, Bryan L; Hairgrove, Ross E; York, Daniel C; Walker, Benjamin B; Hercules, Gregory W; Mertesdorf, Lauren M; Patel, Margi; Morgan, Caurnel

    2014-06-22

    Anorexia and anxiety cause significant mortality and disability with female biases and frequent comorbidity after puberty, but the scarcity of suitable animal models impedes understanding of their biological underpinnings. It is reported here that in adult or weanling Syrian hamsters, relative to social housing (SH), social separation (SS) induced anorexia characterized as hypophagia, weight loss, reduced adiposity, and hypermetabolism. Following anorexia, SS increased reluctance to feed, and thigmotaxis, in anxiogenic environments. Importantly, anorexia and anxiety were induced post-puberty with female biases. SS also reduced hypothalamic corticotrophin-releasing factor mRNA and serum corticosteroid levels assessed by RT-PCR and RIA, respectively. Consistent with the view that sex differences in adrenal suppression contributed to female biases in anorexia and anxiety by disinhibiting neuroimmune activity, SS elevated hypothalamic interleukin-6 and toll-like receptor 4 mRNA levels. Although corticosteroids were highest during SH, they were within the physiological range and associated with juvenile-like growth of white adipose, bone, and skeletal muscle. These results suggest that hamsters exhibit plasticity in bioenergetic and emotional phenotypes across puberty without an increase in stress responsiveness. Thus, social separation of hamsters provides a model of sex differences in anorexia and anxiety during adulthood and their pathogeneses during adolescence. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Melanin content of hamster tissues, human tissues, and various melanomas

    Energy Technology Data Exchange (ETDEWEB)

    Watts, K.P.; Fairchild, R.G.; Slatkin, D.N.; Greenberg, D.; Packer, S.; Atkins, H.L.; Hannon, S.J.

    1981-02-01

    Melanin content (percentage by weight) was determined in both pigmented and nonpigmented tissues of Syrian golden hamsters bearing Greene melanoma. Melanin content was also measured in various other melanoma models (B-16 in C57 mice, Harding-Passey in BALB/c mice, and KHDD in C3H mice) and in nine human melanomas, as well as in selected normal tissues. The purpose was to evaluate the possible efficacy of chlorpromazine, which is known to bind to melanin, as a vehicle for boron transport in neutron capture therapy. Successful therapy would depend upon selective uptake and absolute concentration of borated compounds in tumors; these parameters will in turn depend upon melanin concentration in melanomas and nonpigmented ''background'' tissues. Hamster whole eyes, hamster melanomas, and other well-pigmented animal melanomas were found to contain 0.3 to 0.8% melanin by weight, whereas human melanomas varied from 0.1 to 0.9% (average, 0.35%). Other tissues, with the exception of skin, were lower in content by a factor of greater than or equal to30. Melanin pigment was extracted from tissues, and the melanin content was determined spectrophotometrically. Measurements were found to be sensitive to the presence of other proteins. Previous procedures for isolating and quantifying melanin often neglected the importance of removing proteins and other interfering nonmelanic substances.

  1. Effects of hyperthermia on the hamster immune system

    International Nuclear Information System (INIS)

    Gangavalli, R.; Cain, C.A.; Tompkins, W.A.F.

    1984-01-01

    In previous studies, the authors have shown that hyperthermia can enhance antibody-complement chytotoxicity of hamster and human tumor cells. Moreover, whole body microwave exposure of hamsters resulted in activation of peritoneal macrophages to a viricidal state and transient suppression of natural killer (NK) cell activity. In this study, the authors compare the effects of whole body heating by microwaves or by an environmental chamber (hot air) on the hamster immune system. Microwave exposure (25mW/cm/sup 2/; 1 hr) caused viricidal activation of peritoneal macrophages which resulted in restriction of vaccinia and vesicular stomatitis virs (VSV) growth. However, heating in an environmental chamber (41 0 C; 1 hr) did not activate macrophages to a viricidal state. Both microwave and hot air hyperthermia caused significant augmentation of antibody producing spleen cell response to sheep red blood cells (SRBC), using the Jerne hymolytic plaque assay, four days post exposure and immunization with SRBC. Natural killer spleen cell cytotoxicity was suppressed by microwave and hot air hyperthermia showing that NK lymphocytes are extremely sensitive to changes in temperature. These alterations in cellular immune response due to hyperthermia could be of significance in treatment of tumors and viral infections

  2. Beliefs about the use of baby walkers.

    Science.gov (United States)

    Chagas, Paula S C; Mancini, Marisa C; Tirado, Marcella G A; Megale, Luiz; Sampaio, Rosana F

    2011-01-01

    To understand the opinion of the parents about the baby walker and compare the age of gait acquisition between infants that used a walker and those that did not. In this quali-quantitative study, an interview involving a semi-structured questionnaire was carried out with 26 parents, 14 of whose infants used the equipment (BWG) and 12 of whose infants did not (NBWG) prior to gait acquisition. After extensive content analysis, categories for interpreting the results emerged. For data triangulation, the age of gait acquisition was documented by weekly telephone contact. Student's t-test was used for comparison between groups with a significance level of α=0.05. The following categories were identified in the parents' reports: a) information about the baby walker; b) doubt/decision to use it vs. certainty about not using it; c) beliefs about the use of a baby-walker; and d) benefits and harm from use. The age of independent gait acquisition did not differ between groups (p=0.837): BWG initiated gait at 376.17 (SD=32.62) days and NBWG did so at 378.75 (SD=27.99) days. The beliefs and feelings that permeate the decision to use a baby walker illustrate the different rationales adopted by parents about the role of this equipment in the child's development of gait and autonomy. The use of a baby walker did not influence the age of gait acquisition. The results broaden the understanding of choices that influence child-rearing practices prior to gait acquisition.

  3. Prevalence of intestinal parasites in hamsters and rabbits in some pet shops of Turkey.

    Science.gov (United States)

    Sürsal, Neslihan; Gökpinar, Sami; Yildiz, Kader

    2014-06-01

    In this study, we aimed to determine the parasite species carried by hamsters and rabbits purchased from some commercial pet shops in Turkey. For this purpose, the fecal samples of clinically healthy Syrian hamsters, dwarf hamsters, and crossbred rabbits were collected from 22 pet shops randomly selected in Ankara and Kirikkale provinces, located in Central Anatolia Region of Turkey. The fecal samples were examined with centrifuge flotation technique using saturated salt solution. Parasitic infection rate was 57.5% in dwarf hamsters, 54.9% in Syrian hamsters, and 56.3% in crossbreed rabbits. Trichurid eggs were the most prevalent parasite in the feces of Syrians hamsters (28.1%). The other parasites of Syrian hamsters were as follows: Eimeria spp. oocysts (15.4%) and the eggs of H. nana (11.2%), Syphacia spp. (11%). and Aspiculuris spp. (5.6 %). Only trichurid eggs were observed in the fecal samples of dwarf hamsters (51.5%). Oocysts of Eimeria spp. (52.7%) and the eggs of P. ambiguus (3.6%) were detected in the feces of rabbits. Within the scope of this study, the detection of H. nana eggs, a zoonotic parasite, in the feces of Syrian hamster was quite remarkable for public health.

  4. OEIS complex with glomerulocystic kidney disease: a case report.

    Science.gov (United States)

    Hong, Ran; Lim, Sung-Chul; Jang, Jung-Whan; Suh, Chae-Hong; Jeon, Ho-Jong; Lee, Mi-Ja; Kim, Youn-Shin

    2007-01-01

    We present a case of OEIS complex (omphalocele, exstrophy of bladder, imperforated anus, spinal defect) combined with colonic agenesis and glomerulocystic kidney disease (GCKD). The baby was born at 35.2 weeks of gestational age, weighing 2.51 kg. A prenatal ultrasound examination showed spina bifida, hydroureter, and a unilateral polycystic kidney. The postdelivery examination, which included a physical examination, simple X-ray, and pelvic MRI, showed a lower abdominal wall defect through which a small pouch with a segment of bowel protruded, imperforated anus, ambiguous external genitalia, spina bifida with meningomyelocele at the lumbosacral junction, and nonunion of pubic symphysis. The baby underwent surgery, including nephrectomy, colostomy, and repair of the abdominal wall defect. In addition to the abnormalities mentioned, a tailgut as a result of colonic agenesis and 2 appendices were identified in the course of surgery. The result of histopathological examination confirmed the polycystic kidney identified as GCKD. These radiological, surgical, and histopathologic findings are consistent with the OEIS complex. The postoperative course was uneventful during a period of 4 months of follow up. We herein report a case of the very rare OEIS complex in a newborn male baby and review the available literature.

  5. Ultrasonography of the Kidney

    DEFF Research Database (Denmark)

    Lindskov Hansen, Kristoffer; Nielsen, Michael Bachmann; Ewertsen, Caroline

    2016-01-01

    Ultrasonography of the kidneys is essential in the diagnosis and management of kidney-related diseases. The kidneys are easily examined, and most pathological changes in the kidneys are distinguishable with ultrasound. In this pictorial review, the most common findings in renal ultrasound...

  6. Passive smoking in babies: The BIBE study (Brief Intervention in babies. Effectiveness

    Directory of Open Access Journals (Sweden)

    Cabezas Carmen

    2010-12-01

    Full Text Available Abstract Background There is evidence that exposure to passive smoking in general, and in babies in particular, is an important cause of morbimortality. Passive smoking is related to an increased risk of pediatric diseases such as sudden death syndrome, acute respiratory diseases, worsening of asthma, acute-chronic middle ear disease and slowing of lung growth. The objective of this article is to describe the BIBE study protocol. The BIBE study aims to determine the effectiveness of a brief intervention within the context of Primary Care, directed to mothers and fathers that smoke, in order to reduce the exposure of babies to passive smoking (ETS. Methods/Design Cluster randomized field trial (control and intervention group, multicentric and open. Subject: Fathers and/or mothers who are smokers and their babies (under 18 months that attend pediatric services in Primary Care in Catalonia. The measurements will be taken at three points in time, in each of the fathers and/or mothers who respond to a questionnaire regarding their baby's clinical background and characteristics of the baby's exposure, together with variables related to the parents' tobacco consumption. A hair sample of the baby will be taken at the beginning of the study and at six months after the initial visit (biological determination of nicotine. The intervention group will apply a brief intervention in passive smoking after specific training and the control group will apply the habitual care. Discussion Exposure to ETS is an avoidable factor related to infant morbimortality. Interventions to reduce exposure to ETS in babies are potentially beneficial for their health. The BIBE study evaluates an intervention to reduce exposure to ETS that takes advantage of pediatric visits. Interventions in the form of advice, conducted by pediatric professionals, are an excellent opportunity for prevention and protection of infants against the harmful effects of ETS. Trial Registration Clinical

  7. The presence of opioidergic pinealocytes in the pineal gland of the European hamster (Cricetus cricetus): an immunocytochemical study

    DEFF Research Database (Denmark)

    Coto-Montes, A.; Masson-Pévet, M.; Pévet, P.

    1994-01-01

    Neurobiologi, pineal gland, leu-enkephalin, Met-enkephalin, synaptic contacts, paracrine regulation, European hamster, cricetus cricetus (rodents)......Neurobiologi, pineal gland, leu-enkephalin, Met-enkephalin, synaptic contacts, paracrine regulation, European hamster, cricetus cricetus (rodents)...

  8. Andes Virus M Genome Segment is Not Sufficient to Confer the Virulence Associated With Andres Virus in Syrian Hamsters

    National Research Council Canada - National Science Library

    McElroy, A

    2004-01-01

    ...) in North and South America, respectively. Although ANDV causes a lethal HPS-like disease in hamsters, SNV, and all other HPS-associated hantaviruses that have been tested, cause asymptomatic infections of laboratory animals, including hamsters...

  9. Transplantation of hamster lung lesions induced by 239PuO2 or benz(a)pyrene

    International Nuclear Information System (INIS)

    McDonald, K.E.; Sanders, C.L.

    1980-01-01

    None(0%) of 1000 recipients of lung lesions for 239 PuO 2 -exposed hamsters that were transplanted into other hamsters' cheek pouches, developed tumors, whereas 90% of transplants from benz(a)pyrene-induced lung lesions were malignant

  10. Beliefs about the use of baby walkers

    OpenAIRE

    Chagas,Paula S. C.; Mancini,Marisa C.; Tirado,Marcella G. A.; Megale,Luiz; Sampaio,Rosana F.

    2011-01-01

    OBJECTIVES: To understand the opinion of the parents about the baby walker and compare the age of gait acquisition between infants that used a walker and those that did not. METHODS: In this quali-quantitative study, an interview involving a semi-structured questionnaire was carried out with 26 parents, 14 of whose infants used the equipment (BWG) and 12 of whose infants did not (NBWG) prior to gait acquisition. After extensive content analysis, categories for interpreting the results emerged...

  11. Shaken baby syndrome: a nursing perspective.

    Science.gov (United States)

    Chiocca, E M

    1995-01-01

    Child abuse by whiplash-shaking can lead to severe injury in infants, including cerebral damage, neurological defects, blindness, and mental retardation. These findings are seen often without external evidence of head injury. Nurses should suspect shaken baby syndrome (SBS) in infants less than 1 year of age who present with apnea, seizures, lethargy or drowsiness, bradycardia, respiratory difficulty, coma, or death. Subdural and retinal hemorrhages accompanied by the absence of external signs of trauma are hallmarks of the syndrome.

  12. Constipation in babies: Nutritional and behavioral aspects

    Directory of Open Access Journals (Sweden)

    A. A. Tyazheva

    2015-01-01

    Full Text Available Constipation in children remains one of the topical problems of pediatrics and pediatric gastroenterology. Functional constipation accounts for about 95% of its cases. The article deals with the main causes of constipation in babies. An algorithm for the management of an infant with functional constipation involves correction of infant feeding in addition to medical treatment. Dietary fiber deficiency in infants may cause constipation. That is why functional foods should be used for infant feeding.

  13. MODEL SEIR UNTUK EPIDEMI FLU BABI PADA POPULASI BABI DENGAN LAJU KONTAK JENUH

    Directory of Open Access Journals (Sweden)

    M Kharis

    2012-09-01

    Full Text Available Babi merupakan inang alami dari virus influensa yang secara anatomis, fisiologis, dan imunitas mirip (similar dengan yang ada pada manusia. Virus influenza subtipe A yang ada pada manusia yaitu H1N1, H3N2 dan H1N2 merupakan enzootic pada populasi babi di dunia. babi dapat terinfeksi oleh turunan-turunan virus influenza tipe A dari manusia maupun dari burung dan dalam hal ini dianggap sebagai inang sementara (Intermediate hosts dari turunan-turunan virus flu babi yang berpotensi menyebabkan epidemi bahkan pandemi. Evolusi antigenik dari virus influenza pada babi terjadi dengan laju sekitar 6 kali lebih lambat dibandingkan dengan virus influenza pada manusia. Dalam tulisan ini akan dikaji model matematika untuk epidemi flu babi pada populasi babi. Model yang diberikan merupakan model deterministik dengan laju kontak jenuh yang merupakan perumuman dari laju kontak standar. Perumuman ini dinyatakan dengan adanya probabilitas suatu individu melakukan kontak yang dinyatakan sebagai suatu fungsi dari populasi. Pengkajian yang dilakukan meliputi penentuan titik ekuilibrium model matematika dan analisa kestabilannya. Diharapkan hasil kajian ini dapat bermanfaat dalam penanggulangan wabah flu babi pada sumber utama yaitu populasi babi sehingga dapat dilakukan pencegahan sebelum mewabah di populasi manusia. Pigs are a natural host of influenza virus that are similar anatomically, physiologically, and immunity which in humans. Influenza viruses of A subtype in humans are H1N1, H3N2 and H1N2. They are enzootic in the swine population in the world. Pigs can be infected by strains of type A influenza viruses from humans or from birds. Pigs are considered as a temporary host (intermediate hosts of the derivatives of the swine flu virus that has the potential to cause epidemics and even pandemics. Antigenic evolution of influenza viruses in pigs occurred at rate about 6 times slower than the influenza viruses in humans. In this paper the mathematical model

  14. EKSPLORASI HIJUAN PAKAN BABI DAN CARA PENGGUNAANNYA PADA PETERNAKAN BABI TRADISIONAL DI PROVINSI BALI

    Directory of Open Access Journals (Sweden)

    K. Budaarsa

    2015-06-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui jenis-jenis hijauan yang diberikan sebagai pakan ternak babi dan cara penggunaannya di propvinsi Bali. Penelitian dilakukan dengan metode survei di seluruh kabupaten dan kota di Bali. Pengambilan sampel dilakukan dengan teknik stratified random sampling, dengan pengelompokan atas dataran rendah dan dataran tinggi di masing-masing kabupaten dan kota. Pada masing-masing kelompok di ambil 2 orang peternak babi tradisional, sehingga ada 4 peternak yang diwawancarai di masing-masing kabupaten dan kota atau 32 peternak di seluruh Bali. Hasil survei menunjukkan bahwa ada perbedaan hijauan yang diberikan oleh peternak di dataran rendah dan dataran tinggi. Jenis hijauan yang diberikan di dataran rendah antara lain: batang pisang (Musa paradisiaceae, kangkung (Ipomaea aquatica, biah-biah (Limnocharis flava, dan eceng gondok (Eichornia crassipes. Sedamgkan di dataran tinggi antara lain: batang pisang (Musa paradisiaceae, ketela rambat (Ipomaea batatas, daunt alas (Colocasia esculenta daun lamtoro (Leucaena leucocephala dan dag-dagse (Pisonia alba. Batang pisang dominan (95 % diberikan di dataran rendah maupun di dataran tinggi. Pemberian hijauan ada dengan cara direbus ada yang diberikan dalam bentuk segar. Kesimpulan dari penelitian ini adalah terdapat keragaman jenis hijauan pakan babi dan cara pemberiannya antara di dataran rendah dengan dataran tinggi di Bali. Batang pisang merupakan hijauan yang paling banyak digunakan untuk pakan babi pada peternakan babi tradisional, baik pada dataran rendah maupun dataran tinggi.

  15. Effect of prenatal and postnatal photoperiod on spermatogenic development in the Djungarian hamster (Phodopus sungorus sungorus)

    NARCIS (Netherlands)

    van Haaster, L. H.; van Eerdenburg, F. J.; de rooij, D. G.

    1993-01-01

    The effect of the pre- and postnatal daylength on the start of spermatogenesis and further testicular development from day 4 up to day 127 was investigated in Djungarian hamsters. Hamsters were either gestated under long (16 h light:8 h dark) photoperiod and reared under long or short (4 h light:20

  16. Spermatogenesis is accelerated in the immature Djungarian and Chinese hamster and rat

    NARCIS (Netherlands)

    van Haaster, L. H.; de rooij, D. G.

    1993-01-01

    The rate of progression of spermatogenesis was studied in immature Djungarian and Chinese hamsters and Wistar rats by scoring the most advanced cell types present at various ages after birth. From 15 days of age onward, the most advanced cell types in the Djungarian hamsters were formed at a rate

  17. [The annual cycle in the Djungarian Hamster Phodopus sungorus Pallas].

    Science.gov (United States)

    Figala, J; Hoffmann, K; Goldau, G

    1973-06-01

    Seasonal variations in several functions were observed in a strain of Phodopus s. sungorus bred and kept in the laboratory at Erling-Andechs (47° 58'N, 11° 11'E) under natural illumination: 1. During their first winter most hamsters changed into a whitish winter coat (Figs. 2, 5, and 14). The change in fur coloration is described (Fig. 1). In most animals molt into the winter coat started in October or November, and was completed in December. Molt into the summer coat started in January or February, and was completed in March or early April. Hamsters kept at outdoor temperatures started molt into winter pelt earlier, and finished molt into summer pelt later, than animals kept indoors (Figs. 3 and 4). Winter coloration was more extreme in animals kept at outdoor temperatures. 2. Molt into the winter coat was induced in summer by exposing hamsters to short photoperiods (Fig. 6). However, these animals spontaneously changed back into summer fur while remaining under short-day conditions. 3. The animals had a marked annual cycle in body weight with maximum weight in July and August, and minimum weight in December and January, while they were in winter pelage (Figs. 7 and 8). 4. Reproduction was observed only between February and November (Fig. 9). Young were born within 18 days (2 cases) or 19 days (27 cases) after the breeding pairs were established. Mean litter size was 5 (range 1-9) (Fig. 10). Average litter size was smaller in the first litter of a ♀ than in the second, but was smaller again in subsequent litters (Fig. 11). 5. Growth curves of young hamsters were compared with data from the literature (Fig. 12). In the mean ♂ ♂ were heavier than ♀ ♀ (Table 1). 6. The majority of ♂ ♂ showed testis involution during the first winter. The weight of winter testes was about 1/9th that of summer testes (Fig. 13). The cauda epididymidis contained no spermatozoa in winter animals, and many in summer animals. 7. Daily torpor was observed in many animals, but

  18. Effect of deuterium on the circadian period and metabolism in wild-type and tau mutant Syrian hamsters

    NARCIS (Netherlands)

    Oklejewicz, M; Hut, RA; Daan, S

    2000-01-01

    Homozygous tau mutant Syrian hamsters (tau-/-) have a free-running circadian period (tau) around 20 h and a proportionally higher metabolic rate compared with wild-type hamsters (tau+/+) with a period of circa 24 h. In this study, we applied deuterium oxide (D2O) to hamsters to test whether

  19. Presence of amastigotes in the central nervous system of hamsters infected with Leishmania sp. Presença de amastigotas em sistema nervoso central de hamster infectado com Leishmania sp.

    Directory of Open Access Journals (Sweden)

    Elisangela de Oliveira

    2011-06-01

    Full Text Available Visceral leishmaniasis (VL is a severe chronic disease caused by Leishmania (Leishmania infantum chagasi. Better knowledge on the effects caused by this disease can help develop adequate clinical management and treatment. Parasitological and immunohistochemical studies were performed golden hamsters Mesocricetus auratus infected with bone marrow from individuals with VL in the State of Mato Grosso do Sul, central-west Brazil. The effects of parasitism in the spleen, liver, kidneys, lungs, heart and brain of the animals were examined. Eighteen hamsters were inoculated intraperitoneally, and six healthy animals were used as negative controls. The animals were kept in the animal house and checked for clinical signs. Specimens of each organ were examined for the presence of amastigotes. Immunohistochemical technique was performed in all brain specimens and organs negative on the direct examination of parasites. Direct examination of amastigotes was positive in the spleen and liver of all infected animals; 33.3% showed the parasite in the kidneys and lungs, and 16.7% in the heart. Parasitic forms were seen in 83.3% (15/18 of the brain examined. Immunohistochemistry confirmed the results of the direct examination, except in two specimens of lung tissue and in the brain specimens. Other studies are needed to further clarify the effect of the parasite in the central nervous system.A leishmaniose visceral (LV é uma doença crônica grave, causada pelo parasito Leishmania (Leishmania infantum chagasi. Esclarecer as alterações provocadas pela doença é fundamental para que se adotem condutas clínicas e de tratamento adequadas. Com o objetivo de analisar a infecção experimental em hamsters da linhagem golden, Mesocricetus auratus, infectados com tecido de medula óssea de pacientes com LV no Estado de Mato Grosso do Sul, foram realizados estudos parasitológicos e de imunomarcação. Foi verificada a distribuição do parasitismo no baço, f

  20. Mortality in meconium aspiration syndrome in hospitalized babies.

    Science.gov (United States)

    Anwar, Zahid; Butt, Tayyaba Khawar; Kazi, Muhammad Yaqub

    2011-11-01

    To determine the outcome of the babies in terms of mortality with the diagnosis of Meconium Aspiration Syndrome (MAS). An observational study. The Neonatal Unit of Services Institute of Medical Sciences and Services Hospital, Lahore, Pakistan, from February 2008 to January 2009. All the babies admitted to the neonatal unit during the period of study with the diagnosis of MAS were included. At admission, demographic, maternal, antenatal and natal data were recorded on a specific form. The progress of the baby, including need for ventilation, medications, complications and outcome were also followed and documented. One hundred and nine babies admitted with MAS, 32% died. Most of the babies (n=73) were admitted from our obstetrical unit and the rest through the emergency department. Majority (60 of 109) were admitted within the 1st hour of life. Most (14 of 15) of the newborns requiring intubation within 1st hour of life, died. Forty four babies were ventilated and 35 of these babies succumbed. Of ventilated babies, 11 developed pneumothoraces. Seventy two percent (13 out of 18) of expired babies stayed for less than 24 hours. Mortality rate for MAS was higher in the study group as compared to international figures. It was especially high in babies requiring mechanical ventilation in 1st hour of life or with co-existing severe hypoxic ischemic encephalopathy.

  1. Birthing Healthy Babies (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2018-01-11

    Every four and a half minutes a baby is born with a birth defect in the United States. That means nearly 120,000 babies, or about three percent of all babies born each year. In this podcast, Dr. Suzanne Gilboa discusses ways to prevent birth defects.  Created: 1/11/2018 by MMWR.   Date Released: 1/11/2018.

  2. Enhancement of postreplication repair in Chinese hamster cells

    International Nuclear Information System (INIS)

    D'Ambrosio, S.M.; Setlow, R.B.

    1976-01-01

    Alkaline sedimentation profiles of pulse-labeled DNA from Chinese hamster cells showed that DNA from cells treated with N-acetoxy-acetylaminofluorene or ultraviolet radiation was made in segments smaller than those from untreated cells. Cells treated with a small dose (2.5 μM) of N-acetoxy-acetylaminofluorene or(2.5 J . m -2 ) 254-nm radiation, several hours before a larger dose (7 to 10 μM) of N-acetoxy-acetylaminofluorene or 5.0 J . m -2 of 254-nm radiation, also synthesized small DNA after the second dose. However, the rate at which this small DNA was joined together into parental size was appreciably greater than in absence of the small dose. This enhancement of postreplication repair (as a result of the initial small dose) was not observed when cells were incubated with cycloheximide between the two treatments. The results suggest that N-acetoxy-acetylaminofluorene and ultraviolet-damaged DNA from Chinese hamster cells are repaired by similar postreplicative mechanisms that require de novo protein synthesis for enhancement

  3. Differentiation of hamster liver oval cell following Clonorchis sinensis infection.

    Science.gov (United States)

    Yoon, B I; Jung, S Y; Hur, K; Lee, J H; Joo, K H; Lee, Y S; Kim, D Y

    2000-12-01

    Oval cells which appear in the liver after hepatic injuries are suspected to be progenitor cells for both hepatocytes and bile duct cells. Oval cell isolated from the livers of the hamsters treated with diethylnitrosamine and 2-acetylaminofluorene and infected with Clonorchis sinensis (CS). cultured for 2 weeks and evaluated for differentiation and plasticity by electron microscopy and immunohistochemistry. In the CS-uninfected group, glycogen granules and peroxisomes were noted in the cells that were cultured for 2 weeks. Starting at 1 week postculture, immunoreactivity of the cells to cytokeratin 19 markedly decreased but that to albumin and alpha-fetoprotein gradually increased. This means that oval cells isolated from hamsters that were not infected with CS differentiated toward hepatocyte lineage. However, in the CS-infected group, cultured cells contained numerous rough endoplasmic reticulum and showed immunoreactivity that was generally in reverse to that of CS-uninfected group, meaning that cells isolated following CS infection were primed by CS and differentiated toward bile duct cell lineage. The results of this study suggested that oval cells are indeed bipolar progenitor cells for hepatocytes and bile duct cells and can differentiate toward either lineage depending upon the priming factor.

  4. Expression of thioredoxin during progression of hamster and human cholangiocarcinoma.

    Science.gov (United States)

    Yoon, Byung-Il; Kim, Yeong-Hun; Yi, Jung-Yeon; Kang, Min-Soo; Jang, Ja-June; Joo, Kyoung-Hwan; Kim, Yongbaek; McHugh Law, J; Kim, Dae-Yong

    2010-01-01

    Thioredoxin (Trx) is a multifunctional redox protein that has growth-promoting and anti-apoptotic effects on cells and protects cells from endogenous and exogenous free radicals. Recently, altered expression of Trx has been reported in various cancers. In the present study, we investigated altered expression of Trx at the precancerous and carcinogenic phases during cholangiocarcinogenesis in a hamster cholangiocarcinoma (ChC) model, using semiquantitative immunohistochemical and Western blot analyses. Moreover, to determine if the results correlated well with those in human ChCs, we carried out a comparative immunohistochemical study for Trx in tissue-arrayed human ChCs with different grades of tumor cell differentiation. Trx was found highly expressed in the cytoplasm of dysplastic bile ducts with highly abnormal growth patterns and ChCs irrespective of tumor type or tumor cell differentiation. Overexpression of Trx at the precancerous and carcinogenic phases was further supported by significant elevation of Trx protein in Western blotting. The results from the hamster ChCs were in good agreement with those from human ChCs. Our results strongly suggested that the redox regulatory function of Trx plays an important role in bile duct cell transformation and tumor progression during cholangiocarcinogenesis.

  5. Role of luteinizing hormone in luteotropic complex of pregnant hamster

    International Nuclear Information System (INIS)

    Tamura, H.; Greenwald, G.S.

    1987-01-01

    Hamsters were hypophysectomized on day 4 of pregnancy and injected subcutaneously on days 4-7 with various combinations of 200 μg prolactin (Prl), 10 μg follicle-stimulating hormone (FSH), and 20 μg luteinizing hormone (LH) in polyvinylpyrrolidone (PVP) to decrease its rate of absorption or in saline. End points for luteal function on day 8 were maintenance of pregnancy, serum progesterone (P 4 ), luteal weight, and luteal binding for human chorionic gonadotropin, FSH, and Prl. After hypophysectomy, a drastic decline occurred in all parameters including an 89% decrease in luteal weight. Injection of Prl did not maintain pregnancy nor serum P 4 but partially maintained luteal weight and human chorionic gonadotropin binding sites per corpus luteum. The minimal luteotropic complex of Prl and FSH was effective in maintaining pregnancy and significantly increased serum P 4 and Prl and FSH receptors but not to control levels. Thus, the luteotropic activity of LH was only demonstrable when it was injected in a long-acting form; when delivered as a bolus, LH (saline) was luteolytic. P 4 and estradiol were measured by radioimmunoassay. Radioiodinated gonadotropins were prepared. The percentage of tracer reacting with an excess of receptor were 51% of 125 I-FSH and 45.9% of 125 I-hCG using whole homogenates of hamster ovaries

  6. Determination of elements in blood of golden hamster by NAA

    International Nuclear Information System (INIS)

    Aguiar, Rodrigo Oliveira de

    2009-01-01

    In the present study Neutron Activation Analysis technique has been used to determine, simultaneously, some element concentrations of clinical relevance in whole blood samples of golden hamster. The normal range for Br, Ca, Cl K, Mg, Na and S considering 2 σ (Two Standard deviations) was 0.011 0.047 gL -1 (Br); 0.11 0.35 gL -1 (Ca); 2.11 3.75 gL -1 (Cl); 1.35 2.79 gL -1 (K), 0.026 0.090 gL -1 (Mg), 1.03 2.51 gL -1 (Na) e 0.97 2.01 gL -1 (S). The knowledge of these limits became possible to perform clinical investigation in this animal model using whole blood. The comparison with the results from human being whole blood estimation (Hamster and human) became possible to check the similarities or physiologic differences, an important data for animal experimentation. (author)

  7. Presence of nitrates in baby foods marketed in Portugal

    Directory of Open Access Journals (Sweden)

    João Sebastião Rebelo

    2015-12-01

    Full Text Available This study was carried out to determine the current levels of nitrates in baby foods marketed in Lisbon, Portugal to estimate the toxicological risk associated with their intake. The nitrate content was determined in bottled baby foods of four varieties: vegetable-based foods, meat-based foods, fish-based foods, and fruit-based foods. A total of 39 samples were analyzed over the period 2010–2011. Average and median levels of nitrate in baby foods were lower than the maximum limits established by European Union legislation (200 mg kg−1. Median nitrate values in baby foods were 61, 30, 39, and 15 mg kg−1 w/w for vegetable-based baby foods, meat-based baby foods, fish-based baby foods, and fruit-based baby foods, respectively. The estimated nitrate daily intake through bottled baby foods for infants indicate that individually, these foods are not able to induce nitrate toxicity in the children population.

  8. Hollywood and the Baby Boom: A Social History

    OpenAIRE

    Russell, James A.; Whalley, Jim

    2016-01-01

    Between 1946 and 1964 seventy-five million babies were born, dwarfing the generations that preceded and succeeded them. At each stage of its life-cycle, the baby boom's great size has dictated the terms of national policy and public debate. While aspects of this history are well-documented, the relationship between the baby boom and Hollywood has never been explored. And yet, for almost 40 years, baby boomers made up the majority of Hollywood's audience, and since the 1970s, boomers have domi...

  9. Dealing with food allergies in babies and children

    National Research Council Canada - National Science Library

    Joneja, Janice M. Vickerstaff

    2007-01-01

    ... . . . . . . . . . . . . . . . . . . . 25 CHAPTER 3 PreventionofFoodAllergy...33 CHAPTER 4 Symptoms of Food Sensitivity in Babies and Children . . . . . . . . . . . . . . . . 57 CHAPTER 5 Diagnosis...

  10. At Risk for Kidney Disease?

    Science.gov (United States)

    ... Heart Disease Mineral & Bone Disorder Causes of Chronic Kidney Disease Diabetes and high blood pressure are the most ... blood vessels in your kidneys. Other causes of kidney disease Other causes of kidney disease include a genetic ...

  11. The baby has not come: obstructed labour

    Directory of Open Access Journals (Sweden)

    Nancy MacKeith

    2013-02-01

    Full Text Available This article is about how to recognize obstructed labour and deal with it in a way that preserves the life and health of mother and child. It is for midwives and others who work in maternity care and is based on our experiences in Yei, South Sudan. Obstructed labour means that the baby is too big to pass through the birth canal. It can be associated with prolonged labour. Prolonged labour can sometimes be treated, resulting in a normal delivery but a woman in true obstructed labour should be delivered by Caesarean section.

  12. Recognition and management of Shaken Baby Syndrome

    LENUS (Irish Health Repository)

    Nicholson, Alf

    2016-04-01

    Abusive head trauma (previously referred to as Shaken Baby Syndrome) consists of a triad of findings which included subdural haemorrhage, retinal haemorrhages and encephalopathy after receiving a shake injury or blunt trauma to the head. Debate rages regarding the exact mechanism. Previously published reports on abusive head trauma (AHT) highlight the young age of the victims (median 4 months of age), the significant preponderance of male infants (3:1 in most series), the high rate of probable male perpetrators (just over 50%), and relatively high rates of mortality and morbidity

  13. Baby falcon rescued on CERN site

    CERN Document Server

    Harriet Jarlett

    2016-01-01

    This baby falcon was found on Tuesday, 7 June near a car parked in the Building 40 carpark.   Connie Potter, who first saw the bird, contacted CRR (Centre de Réadaptation des Rapaces) at Bardonnex. Following their advice Connie and Chris Thomas managed to pick it up and get it into a box, and waited with the bird at the main gate for the CRR to collect it. The chick will be fed and trained to fly at the Centre in a tunnel, and ultimately released into the wild, probably near CERN. The bird, who has been tagged with ID number 2054, weighed 119 grams.

  14. Misi Baby Spa - Un Mundo para Bebes

    OpenAIRE

    2012-01-01

    Misi Baby Spa es un lugar privilegiado concebido y diseñado especialmente para mamás, papás y bebés. Busca fortalecer el vínculo afectivo entre el núcleo familiar con herramientas como la lúdica, la música y el agua. Aliado con grandes marcas representativas del sector y encadenado a la marca Misi brindará un gran respaldo y garantía de servicio a sus clientes. Hombres y mujeres de clase media alta y alta interesados en el cuidado de y desarrollo de sus hijos, obtendrán en ...

  15. Million Dollar Baby (2004 and Palliative Care

    Directory of Open Access Journals (Sweden)

    José Elías García Sánchez

    2008-10-01

    Full Text Available The worst misfortune that can befall an old, tormented and fearful boxing trainer is that the pupil he is training and of whom he is very fond should have a lesion as serious as a quadriplegia. This is the crux of the plot in Million Dollar Baby. A person who suffers a quadriplegia sees how most of her physical and sensorial abilities disappear and habitually suffers psychological disturbances requiring palliative medical care. Relatives are subjected to great stress and suffering. All these aspects are reflected, in general accurately, in the film.

  16. Baby Culture and the Curriculum of Consumption: A Critical Reading of the Film "Babies"

    Science.gov (United States)

    Maudlin, Julie G.; Sandlin, Jennifer A.; Thaller, Jonel

    2012-01-01

    We focus on the recently emerging "baby culture" that is fostering a curriculum of consumption and consumerism among parents-to-be and infants aged zero-to-three. To gain insight into how the cultural artifacts, practices, and trends emerging from this demographic are shaping the way we think and act in a consumer culture, we investigate…

  17. Manual Activity and Onset of First Words in Babies Exposed and Not Exposed to Baby Signing

    Science.gov (United States)

    Seal, Brenda C.; DePaolis, Rory A.

    2014-01-01

    Support for baby signing (BS) with hearing infants tends to converge toward three camps or positions. Those who advocate BS to advance infant language, literacy, behavioral, and cognitive development rely heavily on anecdotal evidence and social media to support their claims. Those who advocate BS as an introduction to another language, such as…

  18. Baby Minds: Brain-Building Games Your Baby Will Love. Birth to Age Three.

    Science.gov (United States)

    Acredolo, Linda; Goodwyn, Susan

    Recent research points to the inborn abilities of infants and shows how early experiences influence cognitive skills. This book presents activities for parents and their infants--building on activities babies instinctively love--to develop their unique abilities. The book is organized around six intellectual skills: (1) problem solving; (2)…

  19. Do Babies Think? How Do Babies Think? Unit for Child Studies. Selected Papers Number 23.

    Science.gov (United States)

    Phillips, Shelley

    Prior to considering the ability of infants to think, this discussion attempts to dispel prevalent myths about babies' thought processes. The fact that infants do not intentionally manipulate their parents; are not identical; are not simply hedonistic seekers of bodily pleasures; and are not passive, disorganized beings needing training into…

  20. Tests for Kidney Health

    Science.gov (United States)

    ... The Hope Affair A Pairing for Prevention - Boston Classical Music For a Cause A Pairing for Prevention - ... kidney Financial Assistance Kidney patient assistance HelpLine Grants Management System (GMS) login Education & Research Patient Webinars Become ...

  1. American Kidney Fund

    Science.gov (United States)

    ... The Hope Affair A Pairing for Prevention - Boston Classical Music For a Cause A Pairing for Prevention - ... kidney Financial Assistance Kidney patient assistance HelpLine Grants Management System (GMS) login Education & Research Patient Webinars Become ...

  2. Acute Kidney Failure

    Science.gov (United States)

    ... when your kidneys suddenly become unable to filter waste products from your blood. When your kidneys lose their filtering ability, dangerous levels of wastes may accumulate, and your blood's chemical makeup may ...

  3. Kidneys and Urinary Tract

    Science.gov (United States)

    ... kidneys , contains the by-products of our body's metabolism — salts, toxins, and water — that end up in ... blood. Acute kidney failure may be due to bacterial infection, injury, shock, heart failure, poisoning, or drug ...

  4. Diet - chronic kidney disease

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/002442.htm Diet - chronic kidney disease To use the sharing features on this page, ... make changes to your diet when you have chronic kidney disease (CKD). These changes may include limiting fluids, eating ...

  5. Kidney stones - lithotripsy - discharge

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000136.htm Kidney stones and lithotripsy - discharge To use the sharing features on this page, please enable JavaScript. A kidney stone is a solid mass made up of tiny ...

  6. Kidney Disease Basics

    Science.gov (United States)

    ... Is Chronic Kidney Disease? Related Topics English English French Español Section Navigation Chronic Kidney Disease (CKD) What ... tips from the family health reunion guide and speak with your family during special gatherings. Your chances ...

  7. Acquired Cystic Kidney Disease

    Science.gov (United States)

    ... ACKD)? M any people with chronic kid ney disease develop ACKD, a condition in which the kidneys develop fluid-filled sacs called renal (kidney) cysts. ACKD occurs in children and adults. The cysts are more likely to ...

  8. Changes of spontaneous parthenogenetic activation and development potential of golden hamster oocytes during the aging process.

    Science.gov (United States)

    Jiang, Han; Wang, Ce; Guan, Jiyu; Wang, Lingyan; Li, Ziyi

    2015-01-01

    The golden hamster is an excellent animal experimental model for oocyte research. The hamster oocytes are very useful in clinical examination of human spermatozoan activity. Non-fertile oocytes can lead to time-dependent processes of aging, which will affect the results of human spermatozoa examination. As a consequence there is a need to investigate the aging and anti-aging processes of golden hamster oocytes. In order to study the aging processes and parthenogenetic activation of golden hamster oocytes, in vivo oocytes, oocytes cultured with or without cumulus cells, and oocytes treated with Trichostatin A (TSA) or caffeine were collected and investigated. We found that: (1) spontaneous parthenogenetic activation, developmental potential (cleavage rate), and zona pellucida (ZP) hardening undergo age-dependent changes in in vivo, in vitro, and after TSA or caffeine treatment; (2) in vivo, oocytes became spontaneously parthenogenetic 25 h post-hCG treatment; (3) in vitro, cumulus cells did not significantly increase the parthenogenetic activation rate of cultured hamster oocytes; and (4) TSA or caffeine could delay spontaneous oocyte parthenogenetic activation and the aging processes by at least 5h, but also accelerated the hardening of the ZP. These results define the conditions for the aging and anti-aging processes in golden hamster oocytes. TSA and caffeine play roles in controlling spontaneous activation, which could facilitate the storage and use of golden hamster oocytes for studying processes relevant to human reproduction. Copyright © 2014 Elsevier GmbH. All rights reserved.

  9. The senile kidney

    Directory of Open Access Journals (Sweden)

    Denisova Т.Р.

    2015-03-01

    Full Text Available The given work summarizes external data and self-obtained results on development and diagnostic of kidney involution modifications. Article discusses definition of "senile kidney" as a clinical and pathomorphological term. Major statements on pathophysiological causes of age-associated renal disorders and their prognosis, specifics of chronic kidney disease in elderly and senile patients have been reviewed. Phenomenon of renal "multimorbidity" in eldely maximizes worsening risk of unmodifiable kidney function.

  10. Determination of elements in blood of golden hamster by NAA; Determinacao de elementos em sangue de hamster dourado usando AAN

    Energy Technology Data Exchange (ETDEWEB)

    Aguiar, Rodrigo Oliveira de

    2009-07-01

    In the present study Neutron Activation Analysis technique has been used to determine, simultaneously, some element concentrations of clinical relevance in whole blood samples of golden hamster. The normal range for Br, Ca, Cl K, Mg, Na and S considering 2 {sigma} (Two Standard deviations) was 0.011 0.047 gL{sup -1} (Br); 0.11 0.35 gL{sup -1} (Ca); 2.11 3.75 gL{sup -1} (Cl); 1.35 2.79 gL{sup -1} (K), 0.026 0.090 gL{sup -1} (Mg), 1.03 2.51 gL{sup -1} (Na) e 0.97 2.01 gL{sup -1} (S). The knowledge of these limits became possible to perform clinical investigation in this animal model using whole blood. The comparison with the results from human being whole blood estimation (Hamster and human) became possible to check the similarities or physiologic differences, an important data for animal experimentation. (author)

  11. Kidney Cancer in Children

    Science.gov (United States)

    What is Kidney Cancer in Children? Kidney (renal) tumors are very rare in children. Still, the three most common renal tumors found ... treatable and curable. What are the Types of Kidney Cancer in Children? Male urinary tract Medical Illustration Copyright © ...

  12. Postimplantation Whole Embryo Culture Assay for Hamsters: An Alternative to Rat and Mouse

    Directory of Open Access Journals (Sweden)

    Bogdan Wlodarczyk

    2001-01-01

    Full Text Available Postimplantation whole embryo culture (WEC assay for rats and mice has been well established and introduced to many laboratories. Recently WEC technique for rabbits has been developed; however, information on culture of other species is very limited. Knowing the usefulness of hamsters in classical embryotoxicology, we reasoned that hamster WEC could be an alternative model for the most frequently used rat and mouse WEC. Previously we have optimized culture conditions for postimplantation hamster embryos. The aim of this study was to test the susceptibility of hamster embryos cultured in vitro to embryotoxic compounds and to compare our results with those reported by others on rat or mouse embryo culture. For that purpose we choose three known embryotoxic compounds�valproic acid, cadmium chloride, and diethylstilbestrol�and tested them using a postimplantation hamster whole embryo culture assay. Hamster embryos were cultured from 7.5 days gestation for 24 h in a medium consisting of 35% hamster serum and 65% synthetic culture medium (Iscove�s or McCoy 5A. At the end of the culture period, the embryos were examined morphologically, measured with the aid of a computer image analysis system, and total protein content was assessed. All three compounds exhibited dose-related embryotoxic and teratogenic effects in hamster embryos. The malformations observed were similar to those reported on rat and mouse embryos. Comparison of the results with data reported by other authors indicates that hamster embryos cultured in vitromight be more susceptible to embryotoxic stimuli than rat and mouse embryos.

  13. Anthropometry and body composition of south Indian babies at birth.

    Science.gov (United States)

    Muthayya, S; Dwarkanath, P; Thomas, T; Vaz, M; Mhaskar, A; Mhaskar, R; Thomas, A; Bhat, S; Kurpad, Av

    2006-10-01

    To assess the consequences on body composition of increasing birth weight in Indian babies in relation to reported values in Western babies, and to assess the relationship between maternal and neonatal anthropometry and body composition. Prospective observational study. Bangalore City, India. A total of 712 women were recruited at 12.5+/-3.1 weeks of gestation (mean+/-standard deviation, SD) and followed up until delivery; 14.5% were lost to follow-up. Maternal body weight, height, mid upper-arm circumference and skinfold thicknesses were measured at recruitment. Weight and body composition of the baby (skinfold thicknesses, mid upper-arm circumference, derived arm fat index and arm muscle index; AFI and AMI, respectively) were measured at birth in hospital. The mean+/-SD birth weight of all newborns was 2.80+/-0.44 kg. Birth weight was significantly related to the triceps and subscapular skinfold thickness of the baby. In a small number of babies with large birth weight for gestational age, there was a relatively higher normalised AFI relative to AMI than for babies with lower or appropriate birth weight for gestational age. Maternal height and fat-free mass were significantly associated with the baby's length at birth. Skinfold thicknesses in Indian babies were similar to those reported in a Western population with comparable birth weights, and the relationship of AFI to birth weight appeared to be steeper in Indian babies. Thus, measures to increase birth weight in Indian babies should take into account possible adverse consequences on body composition. There were no significant relationships between maternal anthropometry and body composition at birth on multivariate analysis, except for sum of the baby's skinfold thicknesses and maternal fat-free mass (P<0.02).

  14. Massage Changes Babies' Body, Brain and Behavior

    Science.gov (United States)

    Ishikawa, Chihiro; Shiga, Takashi

    Tactile stimulation is an important factor in mother-infant interactions. Many studies on both human and animals have shown that tactile stimulation during the neonatal period has various beneficial effects in the subsequent growth of the body and brain. In particular, massage is often applied to preterm human babies as “touch care”, because tactile stimulation together with kinesthetic stimulation increases body weight, which is accompanied by behavioral development and the changes of endocrine and neural conditions. Among them, the elevation of insulin-like growth factor-1, catecholamine, and vagus nerve activity may underlie the body weight gain. Apart from the body weight gain, tactile stimulation has various effects on the nervous system and endocrine system. For example, it has been reported that tactile stimulation on human and animal babies activates parasympathetic nervous systems, while suppresses the hypothalamic-pituitary-adrenalcortical (HPA) axis, which may be related to the reduction of emotionality, anxiety-like behavior, and pain sensitivity. In addition, animal experiments have shown that tactile stimulation improves learning and memory. Facilitation of the neuronal activity and the morphological changes including the hippocampal synapse may underlie the improvement of the learning and memory. In conclusion, it has been strongly suggested that tactile stimulation in early life has beneficial effects on body, brain structure and function, which are maintained throughout life.

  15. Shaken baby syndrome: does it exist?

    Science.gov (United States)

    Talbert, D G

    2009-02-01

    The original (1993) definition of Shaken Baby Syndrome (SBS) specifies a group of infants with a history of dysphagia, presenting in a comatose state with respiratory difficulty progressing to apnoea or bradycardia requiring cardiopulmonary resuscitation. It is stated that retinal and vitreous haemorrhages are characteristic of SBS, and that subdural haemorrhage caused by shearing forces disrupting small bridging veins is a common result of shaking, but visible cerebral contusions are unusual. Experimental studies of whiplash injuries in primates in the 1960s showed that when coma was induced cerebral contusions were usually visible, but where the impulse was insufficient to induce coma no damage of any sort was found. Two modes of injury were established, having different impulse thresholds. At the lower threshold it was possible to study injury to axons, e.g. compare the effect of varying the plane of rotation, without inducing subdural bleeding. Contusions were usually observed in this mode, which was considered to be due to separation of the pia mater from the cortex due to trabecular tension. Subdural bleeding could be added by raising the impulse above the second threshold. Thus contusions can occur without subdural bleeding but not vice versa in whiplash injury. The SBS definition is internally inconsistent. By specifying that contusions are rarely seen it seems to rule out whiplash on which the concept of Shaken Baby Syndrome is based. The definition is consistent with dysphagic accidents leading to aspiration, a Dysphagic Infant Death Syndrome in which the carer plays no part.

  16. COMMERCIAL BABY PORRIDGES IN NUTRITION OF INFANTS

    Directory of Open Access Journals (Sweden)

    I. N. Zakharova

    2013-01-01

    Full Text Available The article covers the issue of the most important product among additional food for infants — baby porridges. It includes historical data on usage of various cereal crops in human nutrition. A special significance of porridges in culture of food and traditions of Russian population is highlighted. The authors give information about nutritional value and chemical composition of different cereals — buckwheat, rice, pearl-barley, millet, oats etc. A special attention is given to differences in concentrations of nutrients and micronutrients manufactured by different ways from the same kind of cereal. The necessity to feed infants with commercial baby porridges is based in the article. There are also represented characteristics of various commercial porridges for nutrition of infants: hypoallergenic, glutenfree and containing gluten, enriched with pre- and probiotics. The article also contains data on nutritional value of milk and milk-free porridges. The authors raised a discussion on possibility and standards of usage of different additional components, such as sugar, maltodextrin, honey, vanillin, vegetable oils in production of infant porridges. The selection of certain type of porridges as additional food for healthy and infants with different diseases and digestive disorders is based.

  17. Safety evaluation of superabsorbent baby diapers.

    Science.gov (United States)

    Kosemund, Kirstin; Schlatter, Harald; Ochsenhirt, Jennifer L; Krause, Edburga L; Marsman, Daniel S; Erasala, Geetha N

    2009-03-01

    Superabsorbent disposable baby diapers are sophisticated, well-engineered products that provide many benefits including convenience, comfort, exceptional leakage protection, improved hygiene and skin care benefits compared with cloth diapers. Safety assurance is an integral part of the diaper development process at Procter & Gamble, with the goal of ensuring safety for both caregivers and babies. A systematic, stepwise approach to safety assessment starts with a thorough evaluation of new design features and materials, using the principles of general risk assessment including, as appropriate, controlled trials to assess clinical endpoints or independent scientific review of safety data. The majority of the diaper materials are polymers that are safe and do not have inherent toxicity issues. Trace amounts of non-polymeric materials, such as colorants, are assessed based on their skin contact potential. New materials or design features are introduced in marketed products only if they have been shown to be safe under the conditions of recommended or foreseeable use. The product safety continues to be confirmed after launch by means of in-market monitoring. This article provides a broad overview of human safety exposure-based risk assessment used at Procter & Gamble for absorbent hygiene products.

  18. Japan's baby bust: an economic issue?

    Science.gov (United States)

    1998-09-01

    This brief article articulates that the solution to the declining birthrate in Japan is to change the corporate culture and societal values and begin putting the family first. At the present rate of fertility decline, Japan could well have just over 67 million total population in another 100 years, which is 50% of the present total. In 1990, the Finance Minister tried to convince Japanese couples to have more babies by abandoning policies that led women to higher education. The implication is that women would then want to stay at home and have babies. The prosperity of the late 1980s and early 1990s did not encourage higher fertility. The likely reason for low fertility is the male-dominated, corporate culture where male workers leave home early in the morning and work till late at night. Wives are left to care for children and maintain a full-time job. The total fertility rate (TFR) was 3.65 in 1950 and 1.39 in 1998. Both Germany and Italy have lower fertility but higher rates of immigration. The decline in the TFR is responsible for many of the current economic policies. New taxes were introduced in 1997 to pay for social security of the aged, and then the economy stalled. Life expectancies continue to rise. The elderly are a larger proportion of total population than children aged under 15 years. Women marry late, and the divorce rate is high.

  19. Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org.

    Science.gov (United States)

    Hammond, Stephanie; Kaplarevic, Mihailo; Borth, Nicole; Betenbaugh, Michael J; Lee, Kelvin H

    2012-06-01

    The Chinese hamster genome database (http://www.chogenome.org/) is an online resource for the Chinese hamster (Cricetulus griseus) and Chinese hamster ovary (CHO) cell communities. CHO cells are important for biomedical research and are widely used in industry for the production of biopharmaceuticals. The genome of the CHO-K1 cell line was recently sequenced and the CHO community has developed an online resource to facilitate accessibility of the genomic data and the development of genomic tools. Copyright © 2011 Wiley Periodicals, Inc.

  20. Development of the leptospirosis by experimental infection in hamsters (Mesocricetus auratus with Leptospira interrogans serovar Canicola, strain LO4, by intact and scratched skin exposures

    Directory of Open Access Journals (Sweden)

    Carolina de Sousa Américo Batista

    2010-10-01

    Full Text Available The establishment and evolution of leptospirosis in hamster (Mesocricetus auratus by experimental infection with Leptospira interrogans serovar Canicola, LO4 strain, by intact and scratched skin exposures, having as control the intraperitoneal route, were evaluated. Hundred-twenty female hamsters distributed in two groups according to inoculation route (intact and scratched skin were used. Infectious inoculum was constituted by a pure culture of L. interrogans serovar Canicola (strain LO4, isolated from liver from a slaughtered swine in Londrina, Paraná state and typified by agglutinins adsortion technique with monoclonal antibody kit at the Royal Tropical Institute, Amsterdam, the Netherlands. The animals were observed twice a day during 21 days. Animals that died were necropsied and kidneys, liver, genital tract (uterus and ovaries and brain were aseptically collected. On the 21st post-inoculation day, surviving animals were euthanized. In these animals, serum samples were also collected by cardiac puncture to antileptospires agglutinins research using microscopic agglutination test (MAT. Fresh direct microscopy and microbiological culture were used for the detection of leptospires. Scratched skin route induced larger lethality when compared to intact skin route, with establishment and evolution of leptospirosis. On the other hand, intact skin route induced renal and/or genital carrier state more frequently. LO4 strain presented low immunogenic power, characterized by soroconversion at the MAT in only one inoculated animal.

  1. Pineal and pituitary involvement in the photoperiodic regulation of body weight, coat color and testicular size of the Djungarian hamster, Phodopus sungorus.

    Science.gov (United States)

    Niklowitz, P; Hoffmann, K

    1988-09-01

    Hypophysectomy of 40-day-old male hamsters kept under long photoperiods resulted in a change in coat color from the brownish summer coat to the whitish winter coat, within 5 wk of the surgery, cessation of growth, and, most frequently, an additional loss in body weight. The testes of the hypophysectomized animals were involuted within 14 days after surgery. Continuous substitution of prolactin by implantation of two anterior pituitaries under the kidney capsule was able to reverse partly or totally the inhibitory effects of hypophysectomy on coat color and body weight, although there was no influence on testicular volume. The same effects could be achieved by daily s.c. injections of prolactin (100 micrograms ovine-PRL/day) into hypophysectomized hamsters, whereas the injection of adrenocorticopropic hormone (5 IU porcine-ACTH/day) or melanocyte-stimulating hormone (35 micrograms synthetic alpha-MSH/day) was ineffective. Additional pinealectomy influenced neither the inhibitory effects of hypophysectomy on coat pigmentation and body weight nor the stimulatory effects of prolactin substitution in hypophysectomized animals. Thus, the study provides evidence that the effects of the pineal gland on annual changes in body weight and coat color are mediated via the pituitary.

  2. PELUANG DAN TANTANGAN PENGEMBANGAN TERNAK BABI BALI DI KABUPATEN GIANYAR PROVINSI BALI

    Directory of Open Access Journals (Sweden)

    I. W. Suarna

    2016-02-01

    karena komposisi lipatan lemak setelah kulit akan memberikan aroma dan tekstur babi guling yang sangat baik. Produk kuliner asal babi yang sangat digemari dan telah menjadi branding Kabupaten Gianyar adalah babi guling. Sementara, jenis (breed babi yang paling baik untuk diguling adalah babi bali yang menempati jumlah populasi paling kecil di Kabupaten Gianyar. Fenomena kontroversial tersebut perlu dicarikan solusi agar Gianyar tetap menjadi kabupaten yang terkenal dengan babi guling gianyar. Pencermatan terhadap peluang dan tantangan pengembangan babi bali bertumpu pada integrasi lima pilar utama yakni peternak, desa adat, pemerintah daerah, pengusaha, dan akademisi. Sinergisme kelima pilar tersebut menghasilkan strategi pengembangan babi bali sebagai akselerasi mencapai pertumbuhan babi yang lebih cepat sehingga produktivitas pemeliharaan babi bali dapat ditingkatkan tanpa mengurangi kualitas babi bali sebagai komuditas babi guling yang menjanjikan.

  3. Assessment of Fetal Kidney Growth and Birth Weight in an Indigenous Australian Cohort

    Directory of Open Access Journals (Sweden)

    Christopher J. Diehm

    2018-01-01

    Full Text Available Introduction: Indigenous Australians experience higher rates of renal disease and hypertension than non-Indigenous Australians. Low birth weight is recognized as a contributing factor in chronic disease and has been shown to increase the risk of renal failure in adulthood. A smaller kidney volume with fewer nephrons places an individual at risk of hypertension and renal failure. Indigenous Australians have fewer nephrons than non-Indigenous Australians. In this study, intrauterine fetal and kidney growth were evaluated in 174 Indigenous Australian babies throughout gestation in order to record and evaluate fetal growth and kidney size, within a population that is at high risk for chronic illness.Methods: Pregnant women that identified as Indigenous, or non-Indigenous women that were pregnant with a partner who identified as an Indigenous Australian were eligible to participate. Maternal history, smoking status, blood and urine samples and fetal ultrasounds were collected throughout pregnancy. Fetal kidney measurements were collected using ultrasound. Statistical analysis was performed using the Stata 14.1 software package.Results: 15.2% of babies were born prematurely. 44% of the mothers reported smoking in pregnancy. The median birth weight of this cohort was 3,240 g. Male fetuses had higher kidney to body weight ratios than female fetuses (P = 0.02. The birth weights of term neonates whose mothers smoked during pregnancy were lower (327 g, P < 0.001 than the birth weights of term babies from non-smoking mothers. The kidney volumes of babies whose mothers smoked were also smaller (P = 0.02, but were in proportion to body weight.Conclusion: In this cohort of Indigenous women smoking was associated with both increased number of preterm births and with a reduction in birth weights, even of term infants. Since kidney volume is a surrogate measure of nephron number and nephrogenesis is complete at birth, babies whose mothers smoked during pregnancy

  4. Morbidity and outcome of low birthweight babies of adolescent ...

    African Journals Online (AJOL)

    Morbidity and outcome of low birthweight babies of adolescent mothers at Kenyatta National Hospital, Nairobi. ... The babies were divided into two groups according to their mother's age and then compared with respect to episodes of illness, duration of hospital stay, and overall outcome. Results: One hundred and forty two ...

  5. Baby Gymnastics Visualization Guide Using Macromedia Dreamweaver 8.0

    OpenAIRE

    Titasari Budianti; Rahayu Noveandini, SKom., MMSI

    2007-01-01

    This exercise guide visualization using Dreamweaver 8 as an editor in web design. This website explains in infant development, benefits and rules baby gymnastics, and gymnastics movements baby. And on every page there are pictures gymnastic movement and an explanation of the picture.

  6. Retirement Prospects of the Baby Boom Generation: A Different Perspective.

    Science.gov (United States)

    Easterlin, Richard A.; And Others

    1990-01-01

    Examined average economic status of baby boom cohorts as they approach retirement using data on their life cycle income experience. Findings suggest that baby boomers are likely to enter old age in better economic position than preboom cohorts because of deferred marriages, reduced childbearing, and increased labor force participation of wives…

  7. The Effects of Baby Sign Training on Child Development

    Science.gov (United States)

    Mueller, Vannesa; Sepulveda, Amanda; Rodriguez, Sarai

    2014-01-01

    Although Baby Sign is gaining in popularity, there is a scarcity of research supporting its use. The research that has been conducted is conflicting. In the current study, nine families with children ranging in age from six months to two years and five months participated in a baby sign workshop. A pre--post-test design was used to assess the…

  8. Infants' Attention to Synthesised Baby Music and Original Acoustic Music

    Science.gov (United States)

    Merkow, Carla H.; Costa-Giomi, Eugenia

    2014-01-01

    The distinct music genre known as baby music is based on the premise that infants benefit from music "re-orchestrated for their little ears" ("Baby Einstein Takealong Tunes". (2012). Retrieved December 11, 2012, from http://www.babyeinstein.com/en/products/product_explorer/theme/music/62350/Takealong_Tunes.html). We completed a…

  9. Societal trends : the aging baby boom and women's increased independence

    Science.gov (United States)

    1997-12-01

    The two most important societal trends today are the aging baby boom and women's increased independence. This paper compares the travel profiles of women aged 40 to 49(early baby boomers) with women aged 75 and over and with men aged 75 and over (par...

  10. Zuigelingen met een scheef hoofd [Babies with cranial deformity

    NARCIS (Netherlands)

    Feijen, M.M.; Claessens, E.A.; Dovens, A.J.; Vles, J.S.; van der Hulst, R.R.

    2009-01-01

    Plagiocephaly was diagnosed in a baby aged 4 months and brachycephaly in a baby aged 5 months. Positional or deformational plagio- or brachycephaly is characterized by changes in shape and symmetry of the cranial vault. Treatment options are conservative and may include physiotherapy and helmet

  11. Prevalence and outcome of macrosomic babies admitted to special ...

    African Journals Online (AJOL)

    Objective: Macrosomia has been defined as birth weight of 4.0kilogram and above. It is an important risk factor for perinatal asphyxia, birth injuries and fetal death. To determine the prevalence and outcome of management of macrosomic babies admitted to the Special Care Baby Unit (SCBU) of Usmanu Danfodiyo ...

  12. Baby factory syndicates: An emerging child adoption racket in Nigeria

    African Journals Online (AJOL)

    In Nigeria, the recent discovery of criminal syndicates that specialise in the buying and selling of babies by law enforcement agents has called into question the efficacy of the extant institutional framework designed to regulate child adoption process. The concern of this paper is to describe the modus operandi of baby ...

  13. Mitotic spindle proteomics in Chinese hamster ovary cells.

    Directory of Open Access Journals (Sweden)

    Mary Kate Bonner

    Full Text Available Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division. Birth defects and tissue-specific cancers often result from abnormalities in mitotic events. Here, we report a proteomic study of the mitotic spindle from Chinese Hamster Ovary (CHO cells. Four different isolations of metaphase spindles were subjected to Multi-dimensional Protein Identification Technology (MudPIT analysis and tandem mass spectrometry. We identified 1155 proteins and used Gene Ontology (GO analysis to categorize proteins into cellular component groups. We then compared our data to the previously published CHO midbody proteome and identified proteins that are unique to the CHO spindle. Our data represent the first mitotic spindle proteome in CHO cells, which augments the list of mitotic spindle components from mammalian cells.

  14. Estudios inmunologicos en hamsters (Cricetus auratus infectados con Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    Eduardo Monge

    1986-08-01

    Full Text Available Los resultados de este trabajo muestran que el hamster (Cricetus auratus puede ser utilizado como un modelo experimental para estudios inmunológicos en la infección por Schistosoma mansoni. Los datos obtenidos, relativos a inmunidad concomitante, producción de anticuerpo letal e inmunosupresión se asemejan a los conseguidos en otros modelos experimentales ya establecidos. Estas observaciones indican que el hámster, además de ser un hospedero satisfactorio para el mantenimiento del parásito en el laboratorio, puede ser considerado como un modelo experimental alterno cuyo crecimiento y mantenimiento son relativamente simples y además es un animal de fácil manejo.

  15. Chinese hamster pleiotropic multidrug-resistant cells are not radioresistant

    International Nuclear Information System (INIS)

    Mitchell, J.B.; Gamson, J.; Russo, A.; Friedman, N.; DeGraff, W.; Carmichael, J.; Glatstein, E.

    1988-01-01

    The inherent cellular radiosensitivity of a Chinese hamster ovary pleiotropic cell line that is multidrug resistant (CHRC5) was compared to that of its parental cell line (AuxB1). Radiation survival curve parameters n and D0 were 4.5 and 1.1 Gy, respectively, for the CHRC5 line and 5.0 and 1.2 Gy, respectively, for the parental line. Thus, the inherent radiosensitivity of the two lines was similar even though key intracellular free radical scavenging and detoxifying systems employing glutathione, glutathione transferase, and catalase produced enzyme levels that were 2.0-, 1.9-, and 1.9-fold higher, respectively, in the drug-resistant cell line. Glutathione depletion by buthionine sulfoximine resulted in the same extent of aerobic radiosensitization in both lines (approximately 10%). Incorporation of iododeoxyuridine into cellular DNA sensitized both cell lines to radiation. These studies indicate that pleiotropic drug resistance does not necessarily confer radiation resistance

  16. Thyroid function and cold acclimation in the hamster, Mesocricetus auratus

    International Nuclear Information System (INIS)

    Tomasi, T.E.; Horwitz, B.A.

    1987-01-01

    Basal metabolic rate (BMR), thyroxine utilization rate (T 4 U), and triiodothyronine utilization rate (T 3 U) were measured in cold-acclimated (CA) and room temperature-acclimated (RA) male golden hamsters, Mesocricetus auratus. Hormone utilization rates were calculated via the plasma disappearance technique using 125 I-labeled hormones and measuring serum hormone levels via radioimmunoassay. BMR showed a significant 28% increase with cold acclimation. The same cold exposure also produced a 32% increase in T 4 U, and a 204% increase in T 3 U. The much greater increase in T 3 U implies that previous assessments of the relationship between cold acclimation and thyroid function may have been underestimated and that cold exposure induces both quantitative and qualitative changes in thyroid function. It is concluded that in the cold-acclimated state, T 3 U more accurately reflects thyroid function than does T 4 U. A mechanism for the cold-induced change in BMR is proposed

  17. [Attachment theory and baby slings/carriers: technological network formation].

    Science.gov (United States)

    Lu, Zxy-Yann Jane; Lin, Wan-Shiuan

    2011-12-01

    Healthcare providers recognize the important role played by attachment theory in explaining the close relationship between mental health and social behavior in mothers and their children. This paper uses attachment theory in a socio-cultural context to ascertain the mechanism by which baby slings/carriers, a new technology, produced and reproduced the scientific motherhood. It further applies a social history of technology perspective to understand how baby carriers and attachment theory are socially constructed and historically contingent on three major transformations. These transformations include the use of attachment theory-based baby carriers to further scientific motherhood; the use of baby slings/carriers to further the medicalization of breastfeeding and enhance mother-infant attachment; and the use of baby slings/carriers to transform woman's identities by integrating scientific motherhood, independence and fashion. Implications for nursing clinical policy are suggested.

  18. Photoperiod Regulates vgf-Derived Peptide Processing in Siberian Hamsters.

    Directory of Open Access Journals (Sweden)

    Barbara Noli

    Full Text Available VGF mRNA is induced in specific hypothalamic areas of the Siberian hamster upon exposure to short photoperiods, which is associated with a seasonal decrease in appetite and weight loss. Processing of VGF generates multiple bioactive peptides, so the objective of this study was to determine the profile of the VGF-derived peptides in the brain, pituitary and plasma from Siberian hamsters, and to establish whether differential processing might occur in the short day lean state versus long day fat. Antisera against short sequences at the C- or N- termini of proVGF, as well as against NERP-1, TPGH and TLQP peptides, were used for analyses of tissues, and both immunohistochemistry and enzyme linked immunosorbent assay (ELISA coupled with high-performance liquid (HPLC or gel chromatography were carried out. VGF peptide immunoreactivity was found within cortex cholinergic perikarya, in multiple hypothalamic nuclei, including those containing vasopressin, and in pituitary gonadotrophs. ELISA revealed that exposure to short day photoperiod led to a down-regulation of VGF immunoreactivity in the cortex, and a less pronounced decrease in the hypothalamus and pituitary, while the plasma VGF levels were not affected by the photoperiod. HPLC and gel chromatography both confirmed the presence of multiple VGF-derived peptides in these tissues, while gel chromatography showed the presence of the VGF precursor in all tissues tested except for the cortex. These observations are consistent with the view that VGF-derived peptides have pleiotropic actions related to changing photoperiod, possibly by regulating cholinergic systems in the cortex, vasopressin hypothalamic pathways, and the reproductive axis.

  19. Alpha 2-adrenergic receptor turnover in adipose tissue and kidney: irreversible blockade of alpha 2-adrenergic receptors by benextramine

    Energy Technology Data Exchange (ETDEWEB)

    Taouis, M.; Berlan, M.; Lafontan, M.

    1987-01-01

    The recovery of post- and extrasynaptic alpha 2-adrenergic receptor-binding sites was studied in vivo in male golden hamsters after treatment with an irreversible alpha-adrenoceptor antagonist benextramine, a tetramine disulfide that possesses a high affinity for alpha 2-binding sites. The kidney alpha 2-adrenergic receptor number was measured with (/sup 3/H)yohimbine, whereas (/sup 3/H)clonidine was used for fat cell and brain membrane alpha 2-binding site identification. Benextramine treatment of fat cell, kidney, and brain membranes reduced or completely suppressed, in an irreversible manner, (/sup 3/H) clonidine and (/sup 3/H)yohimbine binding without modifying adenosine (A1-receptor) and beta-adrenergic receptor sites. This irreversible binding was also found 1 and 2 hr after intraperitoneal administration of benextramine to the hamsters. Although it bound irreversibly to peripheral and central alpha 2-adrenergic receptors on isolated membranes, benextramine was unable to cross the blood-brain barrier of the hamster at the concentrations used (10-20 mg/kg). After the irreversible blockade, alpha 2-binding sites reappeared in kidney and adipose tissue following a monoexponential time course. Recovery of binding sites was more rapid in kidney than in adipose tissue; the half-lives of the receptor were 31 and 46 hr, respectively in the tissues. The rates of receptor production were 1.5 and 1.8 fmol/mg of protein/hr in kidney and adipose tissue. Reappearance of alpha 2-binding sites was associated with a rapid recovery of function (antilipolytic potencies of alpha 2-agonists) in fat cells inasmuch as occupancy of 15% of (/sup 3/H)clonidine-binding sites was sufficient to promote 40% inhibition of lipolysis. Benextramine is a useful tool to estimate turnover of alpha 2-adrenergic receptors under normal and pathological situations.

  20. Transmission of methicillin-resistant Staphylococcus aureus between human and hamster.

    Science.gov (United States)

    Ferreira, Jorge Pinto; Fowler, Vance G; Correa, Maria T; Lyman, Roberta; Ruffin, Felicia; Anderson, Kevin L

    2011-04-01

    Transmission of methicillin-resistant Staphylococcus aureus (MRSA) between humans and animals is increasingly recognized. We newly document that the transmission of MRSA between human and hamster is possible.

  1. Non-parametric photic entrainment of Djungarian hamsters with different rhythmic phenotypes

    Czech Academy of Sciences Publication Activity Database

    Schöttner, Konrad; Hauer, J.; Weinert, D.

    2016-01-01

    Roč. 33, č. 5 (2016), s. 506-519 ISSN 0742-0528 Institutional support: RVO:60077344 Keywords : delayed activity onset * Djungarian hamster * free-running period Subject RIV: ED - Physiology Impact factor: 2.562, year: 2016

  2. Familial incidence of mammary gland tumours in the Djungarian hamster (Phodopus sungaros): a case report

    Czech Academy of Sciences Publication Activity Database

    Jelínek, F.; Felsberg, Jürgen; Měšťan, M.

    2013-01-01

    Roč. 58, č. 8 (2013), s. 442-448 ISSN 0375-8427 Institutional support: RVO:61388971 Keywords : hamsters * neoplasias * atypical fibrosarcoma Subject RIV: EE - Microbiology, Virology Impact factor: 0.756, year: 2013

  3. A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism

    DEFF Research Database (Denmark)

    Hefzi, Hooman; Ang, Kok Siong; Hanscho, Michael

    2016-01-01

    Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell engineering and bioprocess optimization, we reconstructed the metabolic pathways...

  4. Allometric and radioautographic study on developing parotid gland of the golden hamster at early postnatat period

    International Nuclear Information System (INIS)

    Luca, I.M.S. de

    1989-01-01

    The post-natal development of golden hamster parotid gland and the rate of proliferation of the cells are studied in the first month of the life. A comparative evaluation with other rodents is presented. (M.A.C.) [pt

  5. 7 CFR 319.56-48 - Conditions governing the entry of baby squash and baby courgettes from Zambia.

    Science.gov (United States)

    2010-01-01

    ... (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Fruits and Vegetables § 319.56-48 Conditions governing the entry of baby squash and baby courgettes from... fly traps with an approved protein bait must be placed inside the greenhouses at a density of four...

  6. Seasonal adaptation of dwarf hamsters (Genus Phodopus): differences between species and their geographic origin.

    Science.gov (United States)

    Müller, D; Hauer, J; Schöttner, K; Fritzsche, P; Weinert, D

    2015-12-01

    The genus Phodopus consists of three species--P. campbelli (Pc), P. sungorus (Ps), and P. roborovskii (Pr). They inhabit steppes, semi-deserts, and deserts in continental Asia with a climate changing from a moderate to a hard Continental one with extreme daily and seasonal variations. These different environmental challenges are likely to have consequences for hamsters' morphology, physiology, and behavior. Hamsters of all three species were investigated during the course of the year in the laboratory though using natural lighting and temperature conditions. Motor activity and body temperature were measured continuously, and body mass, testes size, and fur coloration every 1-2 weeks. With regard to the pattern of activity, nearly twice as many Pc as Ps hamsters (25 vs. 14%) failed to respond to changes of photoperiod, whereas all Pr hamsters did. Body mass and testes size were high in summer and low in winter, with the biggest relative change in Ps and the lowest in Pr hamsters. Changes of fur coloration were found in Ps hamsters only. All responding animals (that is excluding Pr), exhibited regular torpor bouts during the short winter days. In autumn, seasonal changes started considerably earlier in Ps hamsters. To investigate the putative causes of these different time courses, a further experiment was performed, to identify the critical photoperiod. Hamsters were kept for 10 weeks under different photoperiods, changing from 16 to 8 h light per day. Motor activity was recorded continuously, to identify responding and non-responding animals. Body mass was measured at the beginning and the end of the experiment, testes mass only at the end. The critical photoperiod was found to be similar in all three species. Though in a further experiment, Pc and Pr hamsters showed a delayed response, whereas the changes in Ps hamsters started immediately following transfer to short-day conditions. The results show that interspecific differences in seasonal adaptation exist, even

  7. Infertility trial outcomes: healthy moms and babies.

    Science.gov (United States)

    Silver, Robert

    2014-05-01

    Traditionally, the primary outcome of infertility trials has been a positive pregnancy test or a clinically recognized pregnancy. However, parents desire a healthy baby that grows up to be a healthy adult, rather than a positive pregnancy test. Too often results of infertility trials are lacking in crucial obstetric details. This is problematic because treatments for infertility have the capacity to increase the risk for a variety of adverse obstetric outcomes. This review will outline important obstetric variables that should be included when reporting infertility research. The rationale for including these data, precise definitions of the variables, and cost-effective strategies for obtaining these obstetric details will be highlighted. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  8. Boltzmann babies in the proper time measure

    Energy Technology Data Exchange (ETDEWEB)

    Bousso, Raphael; Bousso, Raphael; Freivogel, Ben; Yang, I-Sheng

    2007-12-20

    After commenting briefly on the role of the typicality assumption in science, we advocate a phenomenological approach to the cosmological measure problem. Like any other theory, a measure should be simple, general, well defined, and consistent with observation. This allows us to proceed by elimination. As an example, we consider the proper time cutoff on a geodesic congruence. It predicts that typical observers are quantum fluctuations in the early universe, or Boltzmann babies. We sharpen this well-known youngness problem by taking into account the expansion and open spatial geometry of pocket universes. Moreover, we relate the youngness problem directly to the probability distribution for observables, such as the temperature of the cosmic background radiation. We consider a number of modifications of the proper time measure, but find none that would make it compatible with observation.

  9. Facial aesthetics: babies prefer attractiveness to symmetry.

    Science.gov (United States)

    Samuels, Curtis A; Butterworth, George; Roberts, Tony; Graupner, Lida; Hole, Graham

    2013-01-01

    The visual preferences of human infants for faces that varied in their attractiveness and in their symmetry about the midline were explored. The aim was to establish whether infants' visual preference for attractive faces may be mediated by the vertical symmetry of the face. Chimeric faces, made from photographs of attractive and unattractive female faces, were produced by computer graphics. Babies looked longer at normal and at chimeric attractive faces than at normal and at chimeric unattractive faces. There were no developmental differences between the younger and older infants: all preferred to look at the attractive faces. Infants as young as 4 months showed similarity with adults in the 'aesthetic perception' of attractiveness and this preference was not based on the vertical symmetry of the face.

  10. Radioactivity survey of commercial baby foods

    International Nuclear Information System (INIS)

    Miyake, Sadaaki; Higasa, Mamoru; Takahashi, Kunihiko; Urabe, Ken-ichi

    2007-01-01

    Radioactivity survey has been made on 20 baby-food samples which are available in Saitama Prefecture. 54 Mn, 60 Co, 106 Ru, 134 Cs and 144 Ce were out of detection. 137 Cs was detected in 12 samples, the densities being as low as 0.0048-0.38Bq/kg. The highest density was attributed to the milk powder, still being less than 1/500 of the index, 200Bq/kg, determined by Nuclear Safety Commission of Japan for the milk and dairy products. The sample, except dairy products, that showed the highest 137 Cs density was the prune juice (powder), being 0.19Bq/kg, which is less than 1/2, 500 of the index 500Bq/kg for vegetables, grains and meats/eggs/fishes and others. (K.Y.)

  11. The Incredible Years Parents and Babies Program:

    DEFF Research Database (Denmark)

    Pontoppidan, Maiken W.; Klest, Sihu; Sandoy, Tróndur Møller

    2016-01-01

    Introduction Infancy is an important period of life; adverse experiences during this stage can have both immediate and lifelong impacts on the child’s mental health and well-being. This study evaluates the effects of the Incredible Years Parents and Babies (IYPB) program as a universal intervention...... for parents with infants. Method We conducted a pragmatic, two-arm, parallel pilot randomized controlled trial, in which 112 families with newborns were randomized to the IYPB program (76) or usual care (36) with a 2:1 allocation ratio. The primary outcome was parenting confidence measured after 20 weeks......, using the Karitane Parenting Confidence Scale and Parental Stress Scale. Secondary outcomes include measures of parent health, parent-child relationship, infant development, parent-child activities, network, and family income. Interviewers and data analysts were blind to allocation status. Multiple...

  12. Failure to thrive in babies and toddlers.

    Science.gov (United States)

    Goh, Lay Hoon; How, Choon How; Ng, Kar Hui

    2016-06-01

    Failure to thrive in a child is defined as 'lack of expected normal physical growth' or 'failure to gain weight'. Diagnosis requires repeated growth measurements over time using local, age-appropriate growth centile charts. Premature babies with appropriate growth velocity and children with 'catch-down' growth, constitutional growth delay or familial short stature show normal growth variants, and usually do not require further evaluation. In Singapore, the most common cause of failure to thrive in children is malnutrition secondary to psychosocial and caregiver factors. 'Picky eating' is common in the local setting and best managed with an authoritative feeding style from caregivers. Other causes are malabsorption and existing congenital or chronic medical conditions. Child neglect or abuse should always be ruled out. Iron deficiency is the most common complication. The family doctor plays a pivotal role in early detection, timely treatment, appropriate referrals and close monitoring of 'catch-up' growth in these children. Copyright: © Singapore Medical Association.

  13. Babies and Art Museums: welcoming discoveries

    Directory of Open Access Journals (Sweden)

    Cristina Carvalho

    2017-09-01

    Full Text Available BEBÊS E MUSEUS DE ARTE: ACOLHENDO DESCOBERTAS Resumo: a oferta de ações educativas em museus voltadas para bebês provoca a necessidade de estudos que busquem compreender tais ações, contribuindo para a constituição de práticas significativas. A partir dessas atividades, o artigo apresenta uma reflexão sobre a relação entre arte e primeira infância. O texto foi orientado por teóricos que valorizam o aspecto cultural no desenvolvimento infantil, em especial por Rinaldi e Vecchi. Foram utilizados documentos das instituições, como registros fotográficos e artigos, além de observações de algumas atividades. Buscou-se identificar caminhos que podem estimular a extensão do acolhimento ao público de zero a três anos nas instituições culturais. Palavras-chave: Arte. Educação em Museus. Bebês Abstract: The offer of educational actions focused on babies in museums causes the need for studies that seek to understand such actions, contributing to the constitution of significant practices. From these activities the article presents a reflection on the relationship between art and early childhood. The text was guided by theorists who value the cultural aspect in children's development, especially by Rinaldi and Vecchi. Institutional documents were used, such as photographic records and articles, as well as observations of some activities. It sought to identify ways that can stimulate the extension of the reception to the public from zero to three years in cultural institutions. Keywords: Art. Museum Education. Babies.

  14. Experimental infection of hamsters with avian paramyxovirus serotypes 1 to 9

    Directory of Open Access Journals (Sweden)

    Samuel Arthur S

    2011-02-01

    Full Text Available Abstract Avian paramyxoviruses (APMVs are frequently isolated from domestic and wild birds throughout the world and are separated into nine serotypes (APMV-1 to -9. Only in the case of APMV-1, the infection of non-avian species has been investigated. The APMVs presently are being considered as human vaccine vectors. In this study, we evaluated the replication and pathogenicity of all nine APMV serotypes in hamsters. The hamsters were inoculated intranasally with each virus and monitored for clinical disease, pathology, histopathology, virus replication, and seroconversion. On the basis of one or more of these criteria, each of the APMV serotypes was found to replicate in hamsters. The APMVs produced mild or inapparent clinical signs in hamsters except for APMV-9, which produced moderate disease. Gross lesions were observed over the pulmonary surface of hamsters infected with APMV-2 & -3, which showed petechial and ecchymotic hemorrhages, respectively. Replication of all of the APMVs except APMV-5 was confirmed in the nasal turbinates and lungs, indicating a tropism for the respiratory tract. Histologically, the infection resulted in lung lesions consistent with bronchointerstitial pneumonia of varying severity and nasal turbinates with blunting or loss of cilia of the epithelium lining the nasal septa. The majority of APMV-infected hamsters exhibited transient histological lesions that self resolved by 14 days post infection (dpi. All of the hamsters infected with the APMVs produced serotype-specific HI or neutralizing antibodies, confirming virus replication. Taken together, these results demonstrate that all nine known APMV serotypes are capable of replicating in hamsters with minimal disease and pathology.

  15. The Chemistry of Cold: Mechanisms of Torpor Regulation in the Siberian Hamster.

    Science.gov (United States)

    Cubuk, Ceyda; Bank, Jonathan H H; Herwig, Annika

    2016-01-01

    Siberian hamsters use spontaneous daily torpor, a state of hypometabolism and hypothermia, to save energy during winter. Multiple neuroendocrine signals set the scene for spontaneous torpor to occur, and several brain areas have been identified as potential sites for torpor regulation. Here, we summarize the known mechanisms of a fascinating physiological state in the Siberian hamster. ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

  16. Evaluation of the efficacy of a recombinant subunit West Nile vaccine in Syrian golden hamsters.

    Science.gov (United States)

    Siirin, Marina T; Travassos da Rosa, Amelia P A; Newman, Patrick; Weeks-Levy, Carolyn; Coller, Beth-Ann; Xiao, Shu-Yuan; Lieberman, Michael M; Watts, Douglas M

    2008-12-01

    The efficacy of a recombinant subunit West Nile (WN) vaccine candidate was determined in a hamster model of encephalitis. Animals included young, aged, and immunocompromised animals in an effort to simulate key groups at risk of WN virus-induced disease. Groups of aged (12 month old), weanling, and adult hamsters rendered leukopenic after immunization were immunized subcutaneously with a WN virus recombinant envelope protein (WN-80E) with or without WN virus non-structural protein 1 (NS1) mixed with adjuvant or adjuvant alone. A challenge dose of wild-type WN virus was administered to produce 40-100% mortality in the control hamsters. The recombinant antigen preparations containing WN-80E with or without WN NS1 gave similar results. Hamsters in both groups had a strong antibody response after immunization, and none of the aged or weanling animals became ill or developed detectable viremia after challenge with WN virus at 2 weeks after booster vaccination. However, mortality among the control animals (administered adjuvant without antigen) at 2 weeks after booster challenge was 40-60%. In hamsters rendered leukopenic after immunization, survival rates up to 80% were observed, and a low-level viremia was detected in the vaccinated and challenged hamsters. The survival rate was significantly (Psurvival after challenge. In contrast, all of the control animals that received adjuvant only developed a very high level of viremia, and the mortality rate was 100%. These findings indicate that the recombinant WN vaccines induced antibody in and afforded protection to young and aged hamsters and immunosuppressed hamsters.

  17. MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie.

    OpenAIRE

    Adjou, K T; Demaimay, R; Lasmezas, C; Deslys, J P; Seman, M; Dormont, D

    1995-01-01

    To test the efficacy of a new amphotericin B derivative, MS-8209, in delaying scrapie, hamsters were infected intracerebrally with the 263K scrapie agent and treated with MS-8209 either early in the course of the disease or continuously. The results show that (i) all treatments lengthened the incubation period of hamster scrapie, (ii) continuous treatment with MS-8209 doubled the length of the incubation period compared with that observed in infected, untreated animals, and (iii) all treatmen...

  18. Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.

    Science.gov (United States)

    O'Brien, T G; Saladik, D; Diamond, L

    1982-04-01

    The progression of normal Syrian hamster embryo cells to a neoplastic phenotype after treatment with a chemical carcinogen and continuous exposure to phorbol ester tumor promoters was studied in cell culture. Tumor promoters were able to rescue cell lines derived from individual carcinogen-treated colonies from a program of cellular senescence. In general, these cell lines did not grow in soft-agar medium or produce tumors in newborn hamsters at early passages but acquired these properties at later passages. These cell lines were used to study the temporal acquisition of a phenotypic characteristic of neoplastic rather than normal hamster embryo cells: the synergistic induction of the enzyme ornithine decarboxylase (ODC) by tumor promoter and serum growth factors (O'Brien, T. G., Saladik, D., and Diamond, L. Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture. Biochim. Biophys. Acta, 632: 270, 1980). All cell lines that acquired neoplastic status with passage in culture exhibited the synergistic induction of ODC prior to their acquisition of the ability to either grow in soft-agar medium or produce tumors in newborn hamsters. Cell lines that responded to promoters with the synergistic induction of ODC accumulated greater levels of polyamines, especially putrescine, after promoter treatment than did normal cells. Tumor promoters did not affect the percentage of cells labeled with [3H]thymidine in preneoplastic cell lines, a finding similar to previous results in normal and neoplastic hamster cells. These studies demonstrate that tumor promoters can affect the early stages of neoplastic progression in carcinogen-treated Syrian hamster embryo cells and that a particular phenotypic property found in neoplastic hamster cells, the synergistic induction of ODC by tumor promoters and serum growth factors, is acquired by cell lines before they acquire neoplastic potential.

  19. Cutaneous myxosarcoma in a Syrian hamster (Mesocricetus auratusMixossarcoma cutâneo em um Hamster Sírio

    Directory of Open Access Journals (Sweden)

    Renée Laufer Amorim

    2011-08-01

    Full Text Available The pathological findings in a 2-years-old Syrian hamster (Mesocricetus auratus with a cutaneous myxosarcoma are described. Grossly, there was a large cutaneous mass in the right cervical region. Microscopical evaluation revealed a myxosarcoma characterized by pleomorphic, fusiform cells loosely arranged, randomly distributed, and presenting a moderate amount of basophilic amorphous stroma. There were hemorrhagic areas within the tumor. The basophilic amorphous stroma was positive to Alcian blue confirming the presence of a mucopolysaccharide matrix. Immunohistochemically, the neoplastic cells expressed vimentin, and were negative for cytokeratin or glial fibrillary acidic protein (GFAP.São descritos os achados anatomopatológicos de um caso de mixossarcoma cutâneo em um Hamster Sírio de 2 anos de idade. Macroscopicamente, foi evidenciada um grande massa cutânea na região cervical lateral direita. A microscopia revelou a presença de um caso de mixossarcoma caracterizado por células fusiformes pleomórficas, frouxamente arranjadas, distribuídas aleatoriamente e, apresentando quantidade moderada de substância basofílica amorfa no estroma e áreas hemorrágicas. O estroma basofílico amorfo foi positivo na coloração Alcian blue, confirmando a presença de matriz mucopolissacarídea. Na imunoistoquímica, as células neoplásicas expressaram vimentina e foram negativas para a marcação de citoqueratina e proteína ácida fibrilar (GFAP.

  20. Abandoned babies in the UK - a review utilizing media reports.

    Science.gov (United States)

    Sherr, L; Mueller, J; Fox, Z

    2009-05-01

    In the absence of national policy or comprehensive data, the phenomenon of abandoned babies is poorly understood in the UK. This study aims to use media reports as a resource to collate existing information on abandoned babies and to draw conclusions to inform future response. An exhaustive media search using electronic searches and media monitoring was undertaken to glean systematic information on all abandoned babies in the UK from 1998-2005. These were matched onto two databases - the UK Crime Statistics and the UK Abandoned Children Register in an attempt to align information on infant abandonment. Media reports were coded to list gender, survival, age, parental finding and circumstantial data. Our figures suggest an average of 16 babies abandoned yearly, while official sources give conflicting indications because of incomplete data gathering and child over-inclusion. Through systematic coding of media reports, 124 babies were identified over a 7-year period. Of these, 96 (77.4%) were newborns (1 week old). Adjusted logistic regression analysis found the strongest predictors of survival were age at abandonment and 'findability'. Newborn babies were less likely to survive than older babies (33.7% newborns died vs. 0% older babies, P < 0.0001). Babies left in a non-findable location (34%) had a 5.19 (2.06, 13.11) higher odds of death compared with those to be found. Most babies (74%) were abandoned outdoors and only 9.7% were left with a memento. Few mothers, almost exclusively those of older babies, were found (37.1%). Of those found, 92% were located within 3 days of abandoning their baby. Media interest is transient - 44.8% cases have a single report - and are typified by negative headlines (81.5%). This database currently represents the most accurate and comprehensive picture of the newborn abandonment phenomenon in the UK, a phenomenon that is rare but with high media and social interest. If the future well-being of mother and baby are to be catered for

  1. Genomic organization and expression of immunoglobulin genes in the Chinese hamster (Cricetulus griseus).

    Science.gov (United States)

    Qin, T; Zhu, H; Wang, D; Hao, H; Du, W

    2015-01-01

    In science, the hamsters are widely used as a model for studying the human diseases because they display many features like humans. The utility of the Chinese hamster as a biology model can be further enhanced by further characterization of the genes encoding components of the immune system. Here, we report the genomic organization and expression of the Chinese hamster immunoglobulin heavy and light chain genes. The Chinese hamster IgH locus contains 268 VH segments (132 potentially functional genes, 12 ORFs and 124 pseudogenes), 4 DH segments, 6 JH segments, four constant region genes (μ, γ, ε and α) and one reverse δ remnant fragment. The Igκ locus contains only a single Cκ gene, 4 Jκ segments and 48 Vκ segments (15 potentially functional genes and 33 pseudogenes), whereas the Igλ locus contains 4 Cλ genes, but only Cλ 3 and Cλ 4 each preceded by a Jλ gene segment. A total of 49 Vλ segments (39 potentially functional genes, 3 ORFs and 7 pseudogenes) were identified. Analysis of junctions of the recombined V(D)J transcripts reveals complex diversity in both expressed H and κ sequences, but the microhomology-directed VJ recombination obviously results in very limited diversity in the Chinese hamster λ gene despite more potential germline-encoded combinatorial diversity. This is the first study to make a comprehensive analysis of the Ig genes in the Chinese hamster, which provides insights into the Ig genes in placental mammals. © 2014 John Wiley & Sons Ltd.

  2. Autoradiographic localization of tritiated dihydrotestosterone in the flank organ of the albino hamster

    International Nuclear Information System (INIS)

    Lucky, A.W.; Eisenfeld, A.J.; Visintin, I.

    1985-01-01

    In the hamster flank organ, the growth of hair and growth of sebaceous glands are androgen-dependent functions. Although dihydrotestosterone (DHT) is known to be a potent stimulator of flank organ growth, there is no information about localization of DHT receptor sites in this organ. The purpose of this study was to use steroid autoradiography to localize DHT receptors in the hamster flank organ. Because steroid hormones are functional when translocated to nuclear receptors, nuclear localization by autoradiography defines receptor sites. In order to be able to visualize autoradiographic grains from radiolabeled androgens around hair follicles, albino hamsters were studied to avoid confusion between the grains and pigment granules which are abundant in the more common Golden Syrian hamster. Mature male hamsters castrated 24 hours earlier were given tritium-labeled dihydrotestosterone ( [ 3 H]DHT). Using the technique of thaw-mount steroid autoradiography, 4-micron unfixed frozen sections were mounted in the dark onto emulsion-coated glass slides and allowed to develop for 4-6 months. [ 3 H]DHT was found to be concentrated over sebocyte nuclei. The label was present peripherally as well as in differentiating sebocytes. There was no nuclear localization of [ 3 H]DHT in animals pretreated with excessive quantities of unlabeled DHT. Steroid metabolites of [ 3 H] DHT were assessed by thin-layer chromatography in paired tissue samples. Most of the label remained with DHT. Uptake was inhibited in the flank organ of hamsters pretreated with unlabeled DHT

  3. Circadian body temperature variability is an indicator of poor prognosis in cardiomyopathic hamsters.

    Science.gov (United States)

    Ahmed, Amany; Gondi, Sreedevi; Cox, Casey; Wang, Suwei; Stupin, Igor V; Shankar, K J; Munir, Shahzeb M; Sobash, Ed; Brewer, Alan; Ferguson, James J; Elayda, Macarthur A; Casscells, S Ward; Wilson, James M

    2010-03-01

    Low body temperature is an independent predictor of poor prognosis in patients with congestive heart failure. The cardiomyopathic hamster develops progressive biventricular dysfunction, resulting in heart failure death at 9 months to 1 year of life. Our goal was to use cardiomyopathic hamsters to examine the relationship between body temperature and heart failure decompensation and death. To this end, we implanted temperature and activity transducers with telemetry into the peritoneal space of 46 male Bio-TO-2 Syrian cardiomyopathic hamsters. Multiple techniques, including computing mean temperature, frequency domain analysis, and nonlinear analysis, were used to determine the most useful method for predicting poor prognosis. Data from 44 hamsters were included in our final analysis. We detected a decline in core body temperature in 98% of the hamsters 8+/-4 days before death (P temperature variation (ie, the circadian rhythm) by using cosinor analysis, which revealed a significant decrease in the amplitude of the body temperature circadian rhythm 8 weeks before death (0.28 degrees C; 95% CI, 0.26-0.31) compared to baseline (0.36 degrees C; 95% CI, 0.34-0.39; P=.005). The decline in the circadian temperature variation preceded all other evidence of decompensation. We conclude that a decrease in the amplitude of the body temperature circadian rhythm precedes fatal decompensation in cardiomyopathic hamsters. Continuous temperature monitoring may be useful in predicting preclinical decompensation in patients with heart failure and in identifying opportunities for therapeutic intervention. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  4. BODY WEIGHT AS A DETERMINANT OF CLINICAL EVOLUTION IN HAMSTERS (Mesocricetus auratus INFECTED WITH Leishmania (Viannia panamensis

    Directory of Open Access Journals (Sweden)

    Angela Maria Gomez-Galindo

    2013-09-01

    Full Text Available SUMMARY The clinical outcome of infection with Leishmania species of the subgenus Viannia in hamster model (Mesocricetus auratus has shown to be different depending on experimental protocol. Body weight has been a relevant determinant of the clinical outcome of the infection in hamsters with visceral leishmaniasis but its importance as a clinical parameter in hamsters with cutaneous leishmaniasis is not known. In this study, the clinical evolution of infection with L. (V panamensis was evaluated in juvenile and adult male hamsters during 11 weeks by comparing clinical parameters such as attitude, temperature, respiratory rate, appearance of the stool, and body weight between infected and non-infected groups. Results showed that body weight decreased in adult hamsters after infection by L. (V panamensis; this observation supports the use of body weight as an additional parameter to define the management or treatment of cutaneous leishmaniasis in infected adult hamsters used as an animal experimental model for leishmaniasis.

  5. Ultrasonography of polycystic kidney

    International Nuclear Information System (INIS)

    Oh, Seung Chul; Cho, Seung Gi; Lee, Kwan Seh; Kim, Kun Sang

    1980-01-01

    Polycystic disease is defined as a heritable disorder with diffuse involvement of both kidneys. The term 'Polycystic disease' comprises at least two separate, genetically different disease-one with an onset typically in childhood (infantile polycystic disease) and the other with an onset typically in adulthood (adult polycystic disease). Adult polycystic kidney disease is the most common form of cystic kidney disease in humans. Ultrasonography is a very useful noninvasive diagnostic modality in the patient with clinically suspected renal diseases as well as screening test. 14 cases of ultrasonography in patient with polycystic kidney were reviewed. All cases show unilateral or bilateral enlarged kidneys. 7 cases reveal kidneys and liver replaced by multiple cysts of varing size. Screening ultrasonography for a familial tree is reported

  6. Epigenetics of kidney disease.

    Science.gov (United States)

    Wanner, Nicola; Bechtel-Walz, Wibke

    2017-07-01

    DNA methylation and histone modifications determine renal programming and the development and progression of renal disease. The identification of the way in which the renal cell epigenome is altered by environmental modifiers driving the onset and progression of renal diseases has extended our understanding of the pathophysiology of kidney disease progression. In this review, we focus on current knowledge concerning the implications of epigenetic modifications during renal disease from early development to chronic kidney disease progression including renal fibrosis, diabetic nephropathy and the translational potential of identifying new biomarkers and treatments for the prevention and therapy of chronic kidney disease and end-stage kidney disease.

  7. Strategies of day care center educators in dealing crying babies

    OpenAIRE

    Lígia Ebner Melchiori; Zélia Maria Mendes Biasoli Alves

    2004-01-01

    The purpose of this study is to explore the views of day care center educators on how they act when babies cry, if they are able to identify the causes of crying and what are the subjection reasons that make them take action or not. Twenty-one caretakers were interviewed about each of the ninety babies, aged 4 to 24 months, under their care, using a semi-structured guide. The results show that overall the proportion of babies that do not cry significantly increases with age. However, crying f...

  8. Gauged BPS baby Skyrmions with quantized magnetic flux

    Science.gov (United States)

    Adam, C.; Wereszczynski, A.

    2017-06-01

    A new type of gauged BPS baby Skyrme model is presented, where the derivative term is just the Schroers current (i.e., gauge invariant and conserved version of the topological current) squared. This class of models has a topological bound saturated for solutions of the pertinent Bogomolnyi equations supplemented by a so-called superpotential equation. In contrast to the gauged BPS baby Skyrme models considered previously, the superpotential equation is linear and, hence, completely solvable. Furthermore, the magnetic flux is quantized in units of 2 π , which allows, in principle, to define this theory on a compact manifold without boundary, unlike all gauged baby Skyrme models considered so far.

  9. Clinical characteristics of potential kidney donors with asymptomatic kidney stones

    OpenAIRE

    Lorenz, Elizabeth C.; Lieske, John C.; Vrtiska, Terri J.; Krambeck, Amy E.; Li, Xujian; Bergstralh, Eric J.; Melton, L. Joseph; Rule, Andrew D.

    2011-01-01

    Background. Patients with symptomatic kidney stones are characterized by older age, male gender, white race, hypertension, obesity, metabolic syndrome and chronic kidney disease. Whether these characteristics differ in patients with asymptomatic kidney stones is unknown.

  10. Fluorescence anisotropy of kidney lipids and membranes of a hibernating mammal.

    Science.gov (United States)

    Montaudon, D; Robert, J; Canguilhem, B

    1986-04-01

    The fluorescence anisotropy of lipids and membranes isolated from kidneys of European hamsters (Cricetus cricetus L.) has been estimated using 1,6-diphenyl-1,3,5-hexatriene as a probe. We have compared in this study the results obtained for two critical periods for a hibernator: winter (torpid state), and summer (active state). The differences were of very low magnitude. A slight increase in anisotropy was noticed in the kidney lipids and microsomal membrane preparations from torpid animals. In contrast, a small decrease in anisotropy was observed in the microsomal lipid extracts of torpid animals. A difference in triglyceride content of winter and summer total kidney lipids was detected, as well as a difference in microsomal protein content between winter and summer membrane preparations. It is hypothesized that the latter observations may explain why the behavior of kidney total lipids and microsomal preparations were different from that presented by kidney microsomal lipids in respect to fluorescence anisotropy. Therefore, only a little, if any, homeoviscous adaptation is exhibited by kidney membranes during hibernation of this mammal.

  11. Syrian Hamster as an Animal Model for the Study of Human Influenza Virus Infection.

    Science.gov (United States)

    Iwatsuki-Horimoto, Kiyoko; Nakajima, Noriko; Ichiko, Yurie; Sakai-Tagawa, Yuko; Noda, Takeshi; Hasegawa, Hideki; Kawaoka, Yoshihiro

    2018-02-15

    Ferrets and mice are frequently used as animal models for influenza research. However, ferrets are demanding in terms of housing space and handling, whereas mice are not naturally susceptible to infection with human influenza A or B viruses. Therefore, prior adaptation of human viruses is required for their use in mice. In addition, there are no mouse-adapted variants of the recent H3N2 viruses, because these viruses do not replicate well in mice. In this study, we investigated the susceptibility of Syrian hamsters to influenza viruses with a view to using the hamster model as an alternative to the mouse model. We found that hamsters are sensitive to influenza viruses, including the recent H3N2 viruses, without adaptation. Although the hamsters did not show weight loss or clinical signs of H3N2 virus infection, we observed pathogenic effects in the respiratory tracts of the infected animals. All of the H3N2 viruses tested replicated in the respiratory organs of the hamsters, and some of them were detected in the nasal washes of infected animals. Moreover, a 2009 pandemic (pdm09) virus and a seasonal H1N1 virus, as well as one of the two H3N2 viruses, but not a type B virus, were transmissible by the airborne route in these hamsters. Hamsters thus have the potential to be a small-animal model for the study of influenza virus infection, including studies of the pathogenicity of H3N2 viruses and other strains, as well as for use in H1N1 virus transmission studies. IMPORTANCE We found that Syrian hamsters are susceptible to human influenza viruses, including the recent H3N2 viruses, without adaptation. We also found that a pdm09 virus and a seasonal H1N1 virus, as well as one of the H3N2 viruses, but not a type B virus tested, are transmitted by the airborne route in these hamsters. Syrian hamsters thus have the potential to be used as a small-animal model for the study of human influenza viruses. Copyright © 2018 American Society for Microbiology.

  12. A lethal disease model for hantavirus pulmonary syndrome in immunosuppressed Syrian hamsters infected with Sin Nombre virus.

    Science.gov (United States)

    Brocato, Rebecca L; Hammerbeck, Christopher D; Bell, Todd M; Wells, Jay B; Queen, Laurie A; Hooper, Jay W

    2014-01-01

    Sin Nombre virus (SNV) is a rodent-borne hantavirus that causes hantavirus pulmonary syndrome (HPS) predominantly in North America. SNV infection of immunocompetent hamsters results in an asymptomatic infection; the only lethal disease model for a pathogenic hantavirus is Andes virus (ANDV) infection of Syrian hamsters. Efforts to create a lethal SNV disease model in hamsters by repeatedly passaging virus through the hamster have demonstrated increased dissemination of the virus but no signs of disease. In this study, we demonstrate that immunosuppression of hamsters through the administration of a combination of dexamethasone and cyclophosphamide, followed by infection with SNV, results in a vascular leak syndrome that accurately mimics both HPS disease in humans and ANDV infection of hamsters. Immunosuppressed hamsters infected with SNV have a mean number of days to death of 13 and display clinical signs associated with HPS, including pulmonary edema. Viral antigen was widely detectable throughout the pulmonary endothelium. Histologic analysis of lung sections showed marked inflammation and edema within the alveolar septa of SNV-infected hamsters, results which are similar to what is exhibited by hamsters infected with ANDV. Importantly, SNV-specific neutralizing polyclonal antibody administered 5 days after SNV infection conferred significant protection against disease. This experiment not only demonstrated that the disease was caused by SNV, it also demonstrated the utility of this animal model for testing candidate medical countermeasures. This is the first report of lethal disease caused by SNV in an adult small-animal model.

  13. Autosomal Dominant Polycystic Kidney Disease

    Science.gov (United States)

    ... RePORT NIH Fact Sheets Home > Autosomal Dominant Polycystic Kidney Disease Small Text Medium Text Large Text Autosomal Dominant Polycystic Kidney Disease YESTERDAY Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted ...

  14. The necessity for T-cryptantigen activation screening in babies with ...

    African Journals Online (AJOL)

    TCA and the fulminant form of NEe with bowel necrosis. TCA in a baby with ... All babies with NEC treated in the neonatal wards at. Tygerberg Hospital ... Bowel necrosis with perforation occurred in all 8 babies with TCA and all required surgery. Table I. The characteristics and outcome of babies with various stages of NEC.

  15. Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters.

    Directory of Open Access Journals (Sweden)

    Richard A Bessen

    Full Text Available Chronic wasting disease (CWD is an emerging prion disease of free-ranging and captive cervids in North America. In this study we established a rodent model for CWD in Syrian golden hamsters that resemble key features of the disease in cervids including cachexia and infection of cardiac muscle. Following one to three serial passages of CWD from white-tailed deer into transgenic mice expressing the hamster prion protein gene, CWD was subsequently passaged into Syrian golden hamsters. In one passage line there were preclinical changes in locomotor activity and a loss of body mass prior to onset of subtle neurological symptoms around 340 days. The clinical symptoms included a prominent wasting disease, similar to cachexia, with a prolonged duration. Other features of CWD in hamsters that were similar to cervid CWD included the brain distribution of the disease-specific isoform of the prion protein, PrP(Sc, prion infection of the central and peripheral neuroendocrine system, and PrP(Sc deposition in cardiac muscle. There was also prominent PrP(Sc deposition in the nasal mucosa on the edge of the olfactory sensory epithelium with the lumen of the nasal airway that could have implications for CWD shedding into nasal secretions and disease transmission. Since the mechanism of wasting disease in prion diseases is unknown this hamster CWD model could provide a means to investigate the physiological basis of cachexia, which we propose is due to a prion-induced endocrinopathy. This prion disease phenotype has not been described in hamsters and we designate it as the 'wasting' or WST strain of hamster CWD.

  16. DEVELOPMENT OF MICE AND HAMSTER EMBRYOS IN KSOMAA AND HECM-6 MEDIUM

    Directory of Open Access Journals (Sweden)

    Bayu Rosadi

    2008-12-01

    Full Text Available The purpose of the present study was to investigate the viability of mice and hamster embryos developed in Kalium Simplex Optimized Medium amino acid (KSOMaa and Hamster Embryo Culture Medium-6 (HECM-6 medium. Female DDY mice were superovulated by injection i.p. of 5 IU Pregnant Mare Serum Gonadotropine (PMSG and 5 IU Human Chorionic Gonadotropine (hCG in 48 h interval, hamster (Phodopus campbelli injected by 2.5 IU PMSG and 2.5 IU hCG 48 h later. Then females were mated with fertile males. Eight-cell embryos were recovered at day 3 after natural mating. The mice embryos were cultured in KSOMaa+5% NBCS (New Born Calf Serum (T1 and HECM-6+5% NBCS (T2, the hamster embryos were cultured in KSOMaa+5% NBCS (T3 and HECM-6 + 5% NBCS (T4 for further development at 37oC in a humidified atmosphere of 5% CO2 in air for 48 h. The examinations were replicated five times. The T1 embryos developed to compact morulla and early blastocyst 100% (140/140, 92.1% (129/140 to blastocyst and expanded blastocyst, and 22.9% (32/140 became hatching/hatched. The T3 reached 100% (60/60 to compact morulla and early blastocyst, 85.0% (51/60 blastocyst, and 48.3% (29/60 expanded blastocyst, no embryo observed hatching/hatced. The T2 embryos had more expanded blastocyst than T3 (P<0.05, hatching/hatched rate higher than T1 and T3 but lower than T4 (P<0.05. Shortly, KSOMaa enable to support 8-cell stage mice and hamster embryo, but the hamster embryo developed lower at expanded blastocyst stage. HECM-6 is more appropriate than KSOMaa to support 8-cell mice embryos development and suitable to develop 8-cell stage hamster embryos.

  17. Understanding Motherhood and Mood - Baby Blues and Beyond

    Science.gov (United States)

    ... Low thyroid levels can cause depressed or irritated moods, problems with sleep and concentration, and weight gain. ... you have the baby blues, you may: Have mood swings Feel sad, anxious, or overwhelmed Have crying ...

  18. Lamellar ichthyosis (collodian baby with severe bilateral ectropion

    Directory of Open Access Journals (Sweden)

    Boparai M

    1988-01-01

    Full Text Available A case of lamellar ichthyosis (collodian baby, is being reported. Skin biopsy has confirmed the diagnosis. Severe bilateral ectropion of thee eyelids was the prominent feature. Management of such cases has been briefly discussed.

  19. CDC Vital Signs: Hepatitis C: Testing Baby Boomers Saves Lives

    Science.gov (United States)

    ... 6 MB] Read the MMWR Science Clips Hepatitis C Testing baby boomers saves lives Recommend on Facebook ... boomers got infected before the dangers of hepatitis C were well known. Anyone can get hepatitis C, ...

  20. INNOVATIVE SPECIFIC PRODUCTS: ORGANIC SPROUTS (MICROGREENS AND SEEDLINGS (BABY LEAVES

    Directory of Open Access Journals (Sweden)

    M. I. Ivanova

    2016-01-01

    Full Text Available The assortment of salad crops, process parameters for production of seedlings (Baby leaf and sprouts (Microgreens is presented. The principles of the selection and sale of salad crops in the local market are recommended.

  1. Hepatitis B Shots Are Recommended for All New Babies

    Science.gov (United States)

    ... by vaccination. Who recommends that all babies get hepatitis B vaccination at birth? Medical groups such as the American Academy of Pediatrics, the American Academy of Family Physicians, the American ...

  2. Baby Teeth Link Autism and Heavy Metals, NIH Study Suggests

    Science.gov (United States)

    ... exposed to long before diagnosis is a major advantage.” The method of using baby teeth to measure ... Feed Connect with Us Contact Us Twitter Facebook Instagram YouTube Flickr More Social Media from NIH Footer ...

  3. Pregnancy Choices: Raising the Baby, Adoption, and Abortion

    Science.gov (United States)

    ... PREGNANCY Pregnancy Choices: Raising the Baby, Adoption, and Abortion • What are my options if I find out ... is financial help available? • If I am considering abortion, what should I know about my state’s laws? • ...

  4. EVALUATION OF ANALYTICAL METHODS FOR DETERMINING PESTICIDES IN BABY FOOD

    Science.gov (United States)

    Three extraction methods and two detection techniques for determining pesticides in baby food were evaluated. The extraction techniques examined were supercritical fluid extraction (SFE), enhanced solvent extraction (ESE), and solid phase extraction (SPE). The detection techni...

  5. Cerebral Palsy Checklist: Babies & Preschoolers (Birth to age 5)

    Science.gov (United States)

    ... your baby, toddler, or preschooler. Step 1: Contact Early Intervention Kids with special needs are entitled by federal ... talking, and self-feeding. These services are called early intervention and can be offered by therapists at home, ...

  6. Your Body After Baby: The First 6 Weeks

    Science.gov (United States)

    ... the baby and around the house. What is vaginal discharge? This is bodily fluid that comes out of your vagina. It is also called lochia. Vaginal discharge may increase during and after pregnancy. After your ...

  7. Should we maintain baby hatches in our society?

    Science.gov (United States)

    Asai, Atsushi; Ishimoto, Hiroko

    2013-02-22

    A baby hatch called the "Stork's Cradle" has been in place at Jikei Hospital in Kumamoto City, Japan, since May 10, 2007. Babyklappes were first established in Germany in 2000, and there are currently more than 90 locations. Attitudes regarding baby hatches are divided in Japan and neither opinions for nor against baby hatches have thus far been overwhelming. To consider the appropriateness of baby hatches, we present and examine the validity of each major objection to establishing baby hatches. There are various objections to baby hatches as follows: It violates a child's right to know the identity of his or her biological parents by allowing anonymous birth; it neglects fulfillment of the biological parents' basic obligation to raise their child and its very availability induces abandonment of infants; some people abuse it for very selfish reasons; it cannot save babies' lives; the rights of one parent can be ignored if the other surrenders a child without his or her consent; it puts a baby in medical jeopardy; and it has no clear legal basis. The authors would argue that there are many plausible refutations for each objection mainly based on priority of child's right to life, pregnant women's vulnerability and necessity of anonymity, social responsibility to protect and raise children, differences between dropping a child off at a baby hatch and child neglect, limited function of social childcare center, inevitability of abuse by a minority of people, necessary distinction between outcomes that occur only because baby hatches exist and those that occur regardless of their existence, important local direct and upmost measures for women in trouble, and difference between ambiguous legality and illegality. We argue that a certain number of baby hatches should continue to be established as a last resort, in a form that can maintain anonymity if the parent dropping the child off so desires. It should be supported if it is initiated with good intentions; if the

  8. Collodion Baby with TGM1 gene mutation

    Directory of Open Access Journals (Sweden)

    Sharma D

    2015-09-01

    Full Text Available Deepak Sharma,1 Basudev Gupta,2 Sweta Shastri,3 Aakash Pandita,1 Smita Pawar4 1Department of Neonatology, Fernandez Hospital, Hyderguda, Hyderabad, Andhra Pradesh, 2Department of Pediatrics, Civil Hospital, Palwal, Haryana, 3Department of Pathology, NKP Salve Medical College, Nagpur, Maharashtra, 4Department of Obstetrics and Gynaecology, Fernandez Hospital, Hyderguda, Hyderabad, Andhra Pradesh, IndiaAbstract: Collodion baby (CB is normally diagnosed at the time of birth and refers to a newborn infant that is delivered with a lambskin-like membrane encompassing the total body surface. CB is not a specific disease entity, but is a common phenotype in conditions like harlequin ichthyosis, lamellar ichthyosis, nonbullous congenital ichthyosiform erythroderma, and trichothiodystrophy. We report a CB that was brought to our department and later diagnosed to have TGM1 gene c.984+1G>A mutation. However, it could not be ascertained whether the infant had lamellar ichthyosis or congenital ichthyosiform erythroderma (both having the same mutation. The infant was lost to follow-up.Keywords: cellophane membrane, c.984+1G>A mutation, lamellar ichthyosis, nonbullous congenital ichthyosiform erythroderma, parchment membrane, TGM1 gene

  9. Baby-led Weaning: A Preliminary Investigation.

    Science.gov (United States)

    D'Andrea, Elisa; Jenkins, Kielyn; Mathews, Maria; Roebothan, Barbara

    2016-06-01

    To date, baby-led weaning (BLW) has not been examined in a Canadian population. This research investigated common BLW practices and compared associated knowledge and perceptions of practicing mothers and health care professionals (HCPs). Sixty-five mothers practicing BLW and 33 HCPs were surveyed using 2 online questionnaires. Mothers were recruited through the Newfoundland and Labrador BLW Facebook page and HCPs via email at 2 regional health authorities. Mothers described BLW in terms of food shape and consistency (whole, solid); however, in practice, some mothers offered puréed foods such as infant cereals. More HCPs than mothers indicated choking, inadequate energy, and iron intake as concerns. Mothers relied on the Facebook page over HCPs for BLW information and support. Although all practicing mothers would recommend BLW to others, less than half (48.5%) of HCPs would support it in their practice. Mothers following BLW vary greatly in their experiences and adherence to BLW. They view the practice and its disadvantages very differently than HCPs. Although most HCPs were aware of BLW, few were familiar with specific practices. HCPs may benefit from a greater understanding of BLW to provide guidance to the growing number of mothers following this practice.

  10. Gender discrimination weighs heavily down on babies.

    Science.gov (United States)

    Koshy, L M

    1995-12-30

    During a pediatric conference in New Delhi, India, physicians compared their experiences with various diseases to the body of knowledge contained in Western-oriented medical textbooks. One physician noted that the most important longterm intervention to prevent low birth weight babies and congenital malformations is social and involves reducing discrimination against women in India. Many childhood disorders, such as thalassemia, can be prevented by proper genetic screening. Children with thalassemia depend upon blood transfusions to survive, yet they can contract serious and life-threatening illness from an unsafe blood supply. Another physician implicated improper handling by parents in habit disorders such as thumb sucking. A report on childhood epilepsy noted that 20% of the cases are resistant to therapy. A session on nephrotic syndrome relayed the practical experiences of the pediatricians. The fact that this syndrome recurs until puberty and, thus, requires longterm management makes it an important pediatric topic. Asthma was described as a condition which is increasing and which parents are afraid to acknowledge. Another physician suggested adding childbirth to the list of medical emergencies in India, since 75% of them are attended by untrained personnel who may contribute to the incidence of death from neonatal tetanus.

  11. Paediatric chronic kidney disease

    African Journals Online (AJOL)

    presence of markers of kidney damage. • Markers of kidney disease include any of the following: • proteinuria (urine dipstick ≥2+ or urine protein:creatinine ratio 5 × the upper limit of normal). • urine sediment abnormalities. • electrolyte and other abnormalities caused by tubular disorders. • histological abnormalities.

  12. Kidney Stones (For Parents)

    Science.gov (United States)

    ... may cause long-term damage to the kidney. Diagnosis If your child has pain in the side, blood in the urine, or ... as soon as possible. If your child has pain along with nausea, vomiting, ... away. To make a diagnosis of kidney stones, the doctor will ask about ...

  13. Paediatric chronic kidney disease

    African Journals Online (AJOL)

    (oliguria) (<1.0 mL/kg/hour). • Serum calcium, phosphate, alkaline phosphatase and plasma parathyroid hormone should be determined to assess bone mineral disease and secondary hyperparathyroidism. • Renal ultrasound is necessary to demonstrate kidney size (small shrunken kidneys are characteristic of CKD) and.

  14. Kidney Stones in Children

    Science.gov (United States)

    ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ...

  15. Kidney Infection (Pyelonephritis)

    Science.gov (United States)

    ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ... Kidney Disease Weight Management Liver Disease Urologic Diseases Endocrine Diseases Diet & Nutrition Blood Diseases Diagnostic Tests La información ...

  16. How Much are Consumers Paying for Organic Baby Food?

    OpenAIRE

    Smith, Travis A.; Huang, Chung L.; Lin, Biing-Hwan

    2009-01-01

    Using retail purchase data, price premiums and discounts associated with household demographics, market factors, and product attributes (focusing on the organic attribute for strained baby food) are estimated using a hedonic pricing model. Results suggest that the organic premium ranges from about 12 to 49 percent in 2004 and from 30 to 52 percent in 2006. Tests for significant changes relative to product attributes show that while the price of conventional baby food has stayed relatively the...

  17. Having Healthy Babies (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-01-19

    Most babies in the United States are born perfectly healthy. However, a small percentage are born with birth defects, and these conditions account for one of every five infant deaths in the United States. In this podcast, Dr. Sarah Tinker discusses ways for women to improve their chances of having a healthy baby.  Created: 1/19/2017 by MMWR.   Date Released: 1/19/2017.

  18. Sex stereotypes influence adults' perception of babies' cries

    OpenAIRE

    Reby, David; Levréro, Florence; Gustafsson, Erik; Mathevon, Nicolas

    2016-01-01

    Background Despite widespread evidence that gender stereotypes influence human parental behavior, their potential effects on adults? perception of babies? cries have been overlooked. In particular, whether adult listeners overgeneralize the sex dimorphism that characterizes the voice of adult speakers (men are lower-pitched than women) to their perception of babies? cries has not been investigated. Methods We used playback experiments combining natural and re-synthesised cries of 3?month-old ...

  19. Search for rhythmicity during hibernation in the European hamster.

    Science.gov (United States)

    Canguilhem, B; Malan, A; Masson-Pévet, M; Nobelis, P; Kirsch, R; Pévet, P; Le Minor, J

    1994-01-01

    Temporal patterns of hibernation were studied by continuous monitoring of body temperature by radiotelemetry over 6 months in European hamsters, Cricetus cricetus, at constant temperature and photoperiod. Entrances into hibernation occurred mostly at the end of the night (0000-0800 hours), while arousals were randomly distributed between day and night. This is at variance with a control of bout duration by a clock with a period of 24 h. Consequently, the timing of entrances implies a phase-resetting of the circadian clock on each arousal. Persistence of circadian rhythmicity with a period different from 24 h during deep hibernation was investigated examining whether the durations of torpor bouts were integer multiples of a constant period. A non-parametric version of the classical contingency test of periodicity was developed for this purpose. Periods ranging from 21 to 29 h were tested. Nine animals out of ten showed at least one significant period in this range (P < 0.01), either below 24 h (21.8 +/- 0.5 h, n = 4) or above (27.3 +/- 0.5 h, n = 7). However, we have found a theoretical model of bout durations for which the contingency test of periodicity sometimes gives false significant results. This indicates that the power of the test is weak. With this reservation our results suggest that a circadian oscillator controls the duration of a bout of hibernation, which would occur after an integer, but variable and possibly temperature-dependent number of cycles.

  20. Obesity induction in hamster that mimics the human clinical condition.

    Science.gov (United States)

    Jordania da Silva, Vivian; Dias, Sílvia Regina Costa; Maioli, Tatiani Uceli; Serafim, Luciana Ribeiro; Furtado, Luis Fernando Viana; Quintão Silva, Maria da Gloria; Faria, Ana Maria Caetano de; Rabelo, Élida Mara Leite

    2017-08-05

    Although obesity is well established in hamsters, studies using diets with high levels of simple carbohydrate associated with lipids are necessary to assess the impact of this type of food in the body. In this study a high sugar and butter diet (HSB) and high temperature were employed towards this end. Obesity was successfully induced at a temperature of 30.3°C to 30.9°C after 38 days feeding the animals an HSB diet. It was shown that although diet is important for the induction of obesity, temperature is also essential because at a temperature slightly below the one required, obesity was not induced, even when the animals were fed for a longer period (150 days).The obese clinical condition was accompanied by biochemical and hematological changes, as increased cholesterol and triglyceride levels and increased leukocyte numbers, similar to alterations observed in obese humans. Furthermore, it was demonstrated that increasing the intake of simple carbohydrates associated with lipids provided evidence of inflammation in obese animals.

  1. Systemic immune response to Acanthamoeba keratitis in the Chinese hamster.

    Science.gov (United States)

    Van Klink, F; Leher, H; Jager, M J; Alizadeh, H; Taylor, W; Niederkorn, J Y

    1997-12-01

    Recrudescence is a common and troubling feature of Acanthamoeba keratitis and suggests that corneal infection with this organism fails to stimulate the systemic immune apparatus. The present study examined the cell-mediated and humoral immune responses to Acanthamoeba keratitis in the Chinese hamster. Corneal infection with A. castellanii failed to induce either delayed-type hypersensitivity (DTH) or serum IgG antibody against parasite antigens. The failure to induce cell-mediated and humoral immunity did not result in anergy or tolerance since subsequent intramuscular (i.m.) immunization with parasite antigens elicited robust DTH and IgG antibody responses. The inability of corneal infections to induce primary cell-mediated immune responses was due to the absence of resident antigen-presenting cells in the central cornea because induction of Langerhans cell (LC) migration into the central cornea prior to infection with Acanthamoeba promoted the development of parasite-specific DTH. Although the presence of resident LC did not promote the development of a primary humoral immune response, subsequent i.m. immunization elicited heightened parasite-specific IgG antibody production which was indicative of an anamnestic response. Collectively, the results indicate that in the absence of resident antigen-presenting cells, corneal infection with Acanthamoeba fails to stimulate primary cell-mediated or humoral immunity. Induction of peripheral LC into the central corneal epithelium promotes the development of parasite-specific DTH, but does not exacerbate corneal disease.

  2. Vitamin K metabolism in Chinese Hamster Ovary cells

    International Nuclear Information System (INIS)

    Hoffman, H.S.

    1986-01-01

    Recent investigations suggest that vitamin K may have functions other than in blood coagulation and calcification. The present study was undertaken to investigate this hypothesis using cells in culture. Chinese Hamster Ovary (CHO) cells were chosen due to their active metabolism and growth and lack of similarity to liver and bone cells, in which vitamin K metabolism is well known. Cells were adapted to serum-free media, incubated in media containing the appropriate concentrations of vitamin K for specified times, scraped from plates, pelleted, extensively washed to remove adhering vitamin K, extracted with chloroform:methanol (2:1, v/v) and analyzed on C18 HPLC columns. Uptake of vitamin K by CHO cells follows saturation kinetics at vitamin K concentrations up to 25 μ M and is transported into cells at the rate of 10 pmol/min. 10 6 cells. After 24 hours, 3 H vitamin K is metabolized by CHO cells to several compounds, the major of which was isolated and identified as vitamin K epoxide. In 3 experiments, after 24 hours, the average cellular uptake of vitamin K was 8% with approximately half being metabolized to vitamin K epoxide. These results demonstrate that vitamin K is metabolized in cells with widely different functions and suggest a generalized function for vitamin K which has yet to be elucidated

  3. Investigation of estrogen receptor functionality in hamster melanoma

    International Nuclear Information System (INIS)

    Hitselberger, M.H.

    1987-01-01

    The biology of hamster melanoma, HM1, was assessed congenitally athymic mice after administration of estradiol. Chronic treatment with this steroid hormone delayed tumor appearance in females, inhibited tumor growth in both sexes and reduced the number of lung metastatic lesions in males. Cytosol and nuclear estrogen receptors were characterized in HM1 cells. Specific binding in both fractions was saturable and indicative of high affinity sites with a mean Kd of 0.22 nM in the cytosol and 1.5 nM in the nucleus. Sucrose density-gradient centrifugation of 3 H-estradiol-labelled cytosol demonstrated a peak in the 8S-9S region, which was completely suppressible by excess diethylstilbesterol. To determine whether the estrogen receptor in HM1 cells was functional, athymic mice received 2.5 μg estradiol or vehicle s.c. and were necroscopied 1, 2, 6 and 24 hr later. Nuclear estrogen receptor content was maximal one hr after injection of estradiol and declined to control levels by 24 hr. This effect was accompanied by a rapid reduction in cytosol estrogen receptor content which returned to control levels by 24 hr. A physiologic dose of estradiol, 0.1 μg, injected one hr prior to necroscopy, produced maximal changes in cytosol and nuclear estrogen receptor content

  4. [Promoting Living Kidney Transplantation].

    Science.gov (United States)

    Lin, Chiu-Chu

    2016-04-01

    Kidney transplantation is the best approach for treating patients with end stage renal disease, offering patients the best chance of returning to normal health. While the techniques used in kidney transplantation surgery are mature and highly successful, there is a severe shortage of donor organs. Statistics show a serious imbalance between organ donations and patients on the waiting list for organ transplantation. Moreover, evidence from empirical studies has shown a better transplantation outcome for patients who receive living donor transplantation than for those who receive organs from cadavers. Although using relatives as donors offers an effective way to reduce the problem of organ shortage, this strategy faces many challenges and many other factors affect the promotion of living donor transplantation. This article elaborates how cultural and psychological factors, kidney transplantation awareness, and ethics and laws impact upon living kidney donations and then proposes coping strategies for promoting living kidney transplantation.

  5. Obesity and kidney disease

    Directory of Open Access Journals (Sweden)

    Geraldo Bezerra da Silva Junior

    Full Text Available Abstract Obesity has been pointed out as an important cause of kidney diseases. Due to its close association with diabetes and hypertension, excess weight and obesity are important risk factors for chronic kidney disease (CKD. Obesity influences CKD development, among other factors, because it predisposes to diabetic nephropathy, hypertensive nephrosclerosis and focal and segmental glomerulosclerosis. Excess weight and obesity are associated with hemodynamic, structural and histological renal changes, in addition to metabolic and biochemical alterations that lead to kidney disease. Adipose tissue is dynamic and it is involved in the production of "adipokines", such as leptin, adiponectin, tumor necrosis factor-α, monocyte chemoattractant protein-1, transforming growth factor-β and angiotensin-II. A series of events is triggered by obesity, including insulin resistance, glucose intolerance, dyslipidemia, atherosclerosis and hypertension. There is evidence that obesity itself can lead to kidney disease development. Further studies are required to better understand the association between obesity and kidney disease.

  6. Postnatal rearrangement of central hemodynamics in surgically born babies

    Directory of Open Access Journals (Sweden)

    T. S. Tumaeva

    2015-01-01

    Full Text Available Objective: to investigate the impact of complicated ante- and intranatal periods on postnatal cardiovascular hemodynamic adaptation in surgically born babies who have suffered hypoxia-ischemia. Patients and methods. A total of 382 full-term neonatal infants were examined. A study group included 117 cesarean born babies who had suffered hypoxia-ischemia. Comparison Group 1 comprised 150 infants who had been born by cesarean section and had no signs of cerebral ischemia. Comparison Group 2 consisted of 65 vaginally born babies following hypoxia-ischemia. A control group included 50 infants of physiological pregnancy and labor. In the first 1—2 days of life, all the neonates underwent EchoCG and determination of structural and hemodynamic parameters by using the standard procedures. Impaired postnatal hemodynamic rearrangement was found in all the babies of the examined groups, particular in those who had been born via cesarean section and sustained hypoxia-ischemia; the magnitude of disadaptation correlated with the severity of hypoxia-ischemia. A delayed reduction of dysfunction beyond the early neonatal period was noted in babies exposed to a combination of perinatal damaging factors. Conclusion. A set of poor ante- and intranatal factors contributes to impaired cardiac hemodynamic adaptation. The babies who have been born via cesarean section and sustained hypoxia-ischemia constitute a group at risk for cardiac abnormality in different age periods.

  7. Colloidon baby – Rare case with preventable complications

    Directory of Open Access Journals (Sweden)

    Janardhan Bommakanti

    2015-01-01

    Full Text Available Colloidon baby is a rare congenital disorder characterized clinical-ly by parchment like taught membrane covering the whole body at the time of birth, which subsequently develops Non bullous ichthyosiform erythroderma or Lamellar ichthyiosis in most cases and in few cases other ichthyosiform disorders. The colloidon membrane spontaneously desquamates within 2 weeks or up to 3 months in few cases. Herein, we present 2 cases of colloidon babies born to consanguineously married couples of which the first baby was born at term by normal vaginal delivery and second baby born prematurely by caesarean section. Both 1st & 2nd baby were delivered in different private hospitals in villages of Nizamabad district, Telangana state and reported to tertiary level children’s hospital in Hyderabad city on 4nd and 6th day of life respectively with complaints of colloidon membrane and macera-tion of skin in diaper area, was admitted in Neonatal intensive care unit (NICU in humidified incubator, treated with emollients, intra-venous fluids and prophylactic antibiotics to avoid complications. Nursing care is of prime importance. This presentation was aimed at stressing not only the importance of early recognition by pedia-trician & timely referral to dermatologist and ophthalmologist for saving life of affected baby but also equal importance to proper nursing care.

  8. Iodine Contents in Baby Food Consumed in Japan

    Directory of Open Access Journals (Sweden)

    Yoshida M.

    2013-04-01

    Full Text Available To evaluate iodine intake in Japanese infants, iodine contents were determined in both commercial and homemade baby food samples consumed in Japan. Fifty-three samples of commercial bottled or retort baby food and 25 samples of homemade baby food for one day were collected and their iodine contents were determined by inductively coupled plasma mass spectrometry after an extraction with 0.5% tetramethylammonium hydroxide. Among the commercial baby food samples, 35 samples showed low iodine values ( 1000 ng/g wet weight. Significantly higher iodine values were observed in 15 samples composed of dishes cooked using kombu (a kind of kelp than other samples. Among the homemade baby food samples, 12 samples brought very low iodine intake (< 1- 24 μg/d, while 5 samples brought very high iodine intake (283-978 μg/d. These results indicate that intermittent high iodine baby food including dishes cooked using kombu contributes to sufficient iodine intake in Japanese infants.

  9. Inorganic arsenic levels in baby rice are of concern

    International Nuclear Information System (INIS)

    Meharg, Andrew A.; Sun, Guoxin; Williams, Paul N.; Adomako, Eureka; Deacon, Claire; Zhu, Yong-Guan; Feldmann, Joerg; Raab, Andrea

    2008-01-01

    Inorganic arsenic is a chronic exposure carcinogen. Analysis of UK baby rice revealed a median inorganic arsenic content (n = 17) of 0.11 mg/kg. By plotting inorganic arsenic against total arsenic, it was found that inorganic concentrations increased linearly up to 0.25 mg/kg total arsenic, then plateaued at 0.16 mg/kg at higher total arsenic concentrations. Inorganic arsenic intake by babies (4-12 months) was considered with respect to current dietary ingestion regulations. It was found that 35% of the baby rice samples analysed would be illegal for sale in China which has regulatory limit of 0.15 mg/kg inorganic arsenic. EU and US food regulations on arsenic are non-existent. When baby inorganic arsenic intake from rice was considered, median consumption (expressed as μg/kg/d) was higher than drinking water maximum exposures predicted for adults in these regions when water intake was expressed on a bodyweight basis. - Median consumption of organic arsenic levels for UK babies from baby rice is above threshold considered safe

  10. Sex stereotypes influence adults' perception of babies' cries.

    Science.gov (United States)

    Reby, David; Levréro, Florence; Gustafsson, Erik; Mathevon, Nicolas

    2016-04-14

    Despite widespread evidence that gender stereotypes influence human parental behavior, their potential effects on adults' perception of babies' cries have been overlooked. In particular, whether adult listeners overgeneralize the sex dimorphism that characterizes the voice of adult speakers (men are lower-pitched than women) to their perception of babies' cries has not been investigated. We used playback experiments combining natural and re-synthesised cries of 3 month-old babies to investigate whether the interindividual variation in the fundamental frequency (pitch) of cries affected adult listeners' identification of the baby's sex, their perception the baby's femininity and masculinity, and whether these biases interacted with their perception of the level of discomfort expressed by the cry. We show that low-pitched cries are more likely to be attributed to boys and high-pitched cries to girls, despite the absence of sex differences in pitch. Moreover, low-pitched boys are perceived as more masculine and high-pitched girls are perceived as more feminine. Finally, adult men rate relatively low-pitched cries as expressing more discomfort when presented as belonging to boys than to girls. Such biases in caregivers' responses to babies' cries may have implications on children's immediate welfare and on the development of their gender identity.

  11. Social housing and social isolation: Impact on stress indices and energy balance in male and female Syrian hamsters (Mesocricetus auratus).

    Science.gov (United States)

    Ross, Amy P; Norvelle, Alisa; Choi, Dennis C; Walton, James C; Albers, H Elliott; Huhman, Kim L

    2017-08-01

    Although Syrian hamsters are thought to be naturally solitary, recent evidence from our laboratory demonstrates that hamsters may actually prefer social contact. Hamsters increase their preference for a location associated with an agonistic encounter regardless of whether they have "won" or "lost". It has also been reported that social housing as well as exposure to intermittent social defeat or to a brief footshock stressor increase food intake and body mass in hamsters. By contrast, it has also been suggested that housing hamsters in social isolation causes anxiety-induced anorexia and reductions in body mass selectively in females. The purpose of this study was to determine the physiological consequences of housing hamsters in social isolation versus in social groups. Male and female hamsters were housed singly or in stable groups of 5 for 4weeks after which they were weighed and trunk blood was collected. In addition, fat pads and thymus and adrenal glands were extracted and weighed. Serum and fecal cortisol were measured using an enzyme-linked immunoassay. Housing condition had no effect on serum or fecal cortisol, but socially housed hamsters displayed modest thymus gland involution. Socially housed females weighed more than did any other group, and socially housed females and males had more fat than did socially isolated hamsters. No wounding or tissue damage occurred in grouped hamsters. Overall, these data suggest that Syrian hamsters tolerate both stable social housing and social isolation in the laboratory although social housing is associated with some alteration in stress-related and bioenergetic measures. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Analisis Spa Bayi dengan Kualitas Tidur Bayi di Lolypop Kids and Baby Spa Medan

    OpenAIRE

    Lubis, Siti Fatimah

    2015-01-01

    Sleeping quality is a quality or certain physiological condition that babies get during their sleeping time, which recovers body’s processes which occurs when the baby wakes up in the right number of time. Sleeping has a very great role in the development of babies. But around 25% of sleeping disturbance occurs on babies so it disturbs the sleeping quality of the babies. Based on the anxiety on sleeping disturbance, parents are getting care more on treatments which can stimulate the fulfillme...

  13. Housing type, location of residence and health status in Australian baby boomers: results from the Australian Baby Boomer (ABBA) Study.

    Science.gov (United States)

    Black, Deborah Ann; Wilson, Leigh Ann; O'Loughlin, Kate; Noone, Jack; Kendig, Hal; Butcher, Jennifer

    2015-03-01

    Baby Boomers are working and living longer than their pre-war counterparts, and are more likely to live in high density urban housing. This paper examines the relationship between housing type, working status and location of residence on health status in Baby Boomers. We investigated location of residence and housing type in 1009 participants of the Ageing Baby Boomers in Australia (ABBA) Study to identify any predictors of, or correlations between, these variables and health status. Current workers were less likely to report depression than retirees. We found a significantly higher rate of diabetes, obesity and hypertension in retirees than in current workers however rates of obesity, diabetes and hypertension were higher than predicted in current workers. The rates of chronic disease are higher than previous estimates and provide evidence to inform health promotion programs designed to increase physical activity and improve eating habits in baby boomers. © 2013 ACOTA.

  14. Effect of dietary fatty acids on metabolic rate and nonshivering thermogenesis in golden hamsters.

    Science.gov (United States)

    Jefimow, Małgorzata; Wojciechowski, Michał S

    2014-02-01

    Hibernating rodents prior to winter tend to select food rich in polyunsaturated fatty acids (PUFA). Several studies found that such diet may positively affect their winter energy budget by enhancing torpor episodes. However, the effect of composition of dietary fatty acids (FA) on metabolism of normothermic heterotherms is poorly understood. Thus we tested whether diets different in FA composition affect metabolic rate (MR) and the capacity for nonshivering thermogenesis (NST) in normothermic golden hamsters (Mesocricetus auratus). Animals were housed in outdoor enclosures from May 2010 to April 2011 and fed a diet enriched with PUFA (i.e., standard food supplemented weekly with sunflower and flax seeds) or with saturated and monounsaturated fatty acids (SFA/MUFA, standard food supplemented with mealworms). Since diet rich in PUFA results in lower MR in hibernating animals, we predicted that PUFA-rich diet would have similar effect on MR of normothermic hamsters, that is, normothermic hamsters on the PUFA diet would have lower metabolic rate in cold and higher NST capacity than hamsters supplemented with SFA/MUFA. Indeed, in winter resting metabolic rate (RMR) below the lower critical temperature was higher and NST capacity was lower in SFA/MUFA-supplemented animals than in PUFA-supplemented ones. These results suggest that the increased capacity for NST in PUFA-supplemented hamsters enables them lower RMR below the lower critical temperature of the thermoneural zone. © 2013 Wiley Periodicals, Inc.

  15. The effect of dietary vitamin A on NO2 exposure on the hamster lung

    International Nuclear Information System (INIS)

    Kim, J.C.

    1978-01-01

    The effect of dietary vitamin A and NO2 exposure on the hamster lung was evaluated by histopathology, electron microscopy, and thymidine uptake studies. Hamsters were maintained on deficient (0 micrograms), adequate (100 micrograms), and high (200 micrograms) dose levels of vitamin A while being exposed repeatedly to 10 ppm of NO2 for 5 hours once a week over an 8-week period. Hamsters of the deficient group exhibited clinical and morphologic changes characteristic of vitamin A deficiency. Animals maintained on adequate and high dose levels of vitamin A were not affected by vitamin A deficiency. Hypertrophy and hyperplasia of the epithelial cells of the terminal bronchiolar alveolar region of lungs of adequately and highly dosed animals were greater than those observed in the deficient animals, when NO2 exposure was given. However, the extent of the lesions observed in all three groups was less than that seen in normal hamsters given a single, 5-hour NO2 exposure. Ultrastructural changes observed in vitamin A-deficient hamsters exposed to NO2 were hypertrophy and hyperplasia of bronchiolar epithelial cells, diffuse loss of cilia, membrane damage, and mitochondrial damage manifested by calcium deposition. Tritiated thymidine uptake studies of lungs of animals exposed repeatedly revealed a rather erratic cell renewal pattern following NO2 exposure in comparison to the group of animals exposed singly

  16. Central vasopressin infusion prevents hibernation in the European hamster (Cricetus cricetus).

    Science.gov (United States)

    Hermes, M L; Buijs, R M; Masson-Pévet, M; van der Woude, T P; Pévet, P; Brenklé, R; Kirsch, R

    1989-01-01

    The amount of immunocytochemically detectable vasopressin in the brain of the European hamster (Cricetus cricetus) shows a seasonal variation; i.e., dense vasopressin immunoreactivity is present in the lateral septum during summer but is absent in autumn and winter [Buijs, R. M., Pévet, P., Masson-Pévet, M., Pool, C. W., De Vries, G. J., Canguilhem, B. & Vivien-Roels, B. (1986) Brain Res. 371, 193-196]. In the winter period the European hamster hibernates. Since vasopressin in the lateral septum is known to be involved in the control of body temperature, we investigated whether infusion of vasopressin in the lateral septum during autumn-winter could influence hypothermic patterns normally seen in hibernating animals. Hamsters whose lateral septum was infused with vasopressin showed almost no periods of hypothermia, whereas hamsters treated with control infusions displayed a normal hibernation pattern. The results indicate that persistence of vasopressin release in the lateral septum of the European hamster during winter can prevent hibernation. Images PMID:2762331

  17. Effects of light deprivation on prolactin regulation in the Golden Syrian hamster

    International Nuclear Information System (INIS)

    Massa, J.S.

    1986-01-01

    Pineal-mediated depressions in prolactin cell activity after light deprivation were studied in the male and female Golden Syrian hamster. Prolactin cell activity was determined by measuring radioimmunoassayable prolactin, newly synthesized prolactin, newly synthesized prolactin and prolactin mRNA levels in the pituitary. Serum prolactin was also measured by radioimmunoassay. Use of the recombinant DNA plasmid, pPRL-1, which contains the rat prolactin complimentary DNA sequence, was validated in this dissertation for measuring prolactin mRNA in the hamster. Male Hamsters blinded for 11, 21, or 42 days showed significant and progressively greater declines in prolactin mRNA levels which were completely prevented by pinealectomy. Female hamsters blinded for 28 days, however, showed no such decreases in prolactin cell activity if they continued to display estrous cyclicity. After 12 weeks of blinding, females were acyclic and had dramatically depressed levels of prolactin cell activity. However, pinealectomy did not completely prevent this decline due to blinding unless the females continue to display estrous cyclicity. In ovariectomized females, blinding caused a decline in prolactin cell activity. In a separate study, significant changes in prolactin cell activity during the estrous cycle were seen in untreated normally cycling female hamsters. These changes in prolactin mRNA, prolactin synthesis, and radioimmunoassayable prolactin in the pituitary were measured in the morning, when, consistent with other reports, no differences in serum prolactin were observed

  18. Stimulatory effect of RFRP-3 on the gonadotrophic axis in the male Syrian hamster

    DEFF Research Database (Denmark)

    Ancel, Caroline; Bentsen, Agnete H; Sébert, Marie-Emilie

    2012-01-01

    In seasonal mammals, a distinct photoneuroendocrine circuit that involves the pineal hormone melatonin tightly synchronizes reproduction with seasons. In the Syrian hamster, a seasonal model in which sexual activity is inhibited by short days, we have previously shown that the potent GnRH stimula......In seasonal mammals, a distinct photoneuroendocrine circuit that involves the pineal hormone melatonin tightly synchronizes reproduction with seasons. In the Syrian hamster, a seasonal model in which sexual activity is inhibited by short days, we have previously shown that the potent Gn...... in the Syrian hamster, is strongly down-regulated by melatonin in short days. Because a large body of evidence now indicates that RFamide-related peptide (RFRP)-3, the product of the rfrp gene, is an inhibitor of gonadotropin secretion in various mammalian species, we sought to investigate its effect...... on the gonadotrophic axis in the Syrian hamster. We show that acute central injection of RFRP-3 induces c-Fos expression in GnRH neurons and increases LH, FSH, and testosterone secretion. Moreover, chronic central administration of RFRP-3 restores testicular activity and Kiss1 levels in the arcuate nucleus of hamsters...

  19. Propagation of Asian isolates of canine distemper virus (CDV in hamster cell lines

    Directory of Open Access Journals (Sweden)

    Yamaguchi Ryoji

    2009-10-01

    Full Text Available Abstract Backgrounds The aim of this study was to confirm the propagation of various canine distemper viruses (CDV in hamster cell lines of HmLu and BHK, since only a little is known about the possibility of propagation of CDV in rodent cells irrespective of their epidemiological importance. Methods The growth of CDV in hamster cell lines was monitored by titration using Vero.dogSLAMtag (Vero-DST cells that had been proven to be susceptible to almost all field isolates of CDV, with the preparations of cell-free and cell-associated virus from the cultures infected with recent Asian isolates of CDV (13 strains and by observing the development of cytopathic effect (CPE in infected cultures of hamster cell lines. Results Eleven of 13 strains grew in HmLu cells, and 12 of 13 strains grew in BHK cells with apparent CPE of cell fusion in the late stage of infection. Two strains and a strain of Asia 1 group could not grow in HmLu cells and BHK cells, respectively. Conclusion The present study demonstrates at the first time that hamster cell lines can propagate the majority of Asian field isolates of CDV. The usage of two hamster cell lines suggested to be useful to characterize the field isolates biologically.

  20. Vasopressin differentially modulates aggression and anxiety in adolescent hamsters administered anabolic steroids.

    Science.gov (United States)

    Morrison, Thomas R; Ricci, Lesley A; Melloni, Richard H

    2016-11-01

    Adolescent Syrian hamsters (Mesocricetus auratus) treated with anabolic/androgenic steroids display increased offensive aggression and decreased anxiety correlated with an increase in vasopressin afferent development, synthesis, and neural signaling within the anterior hypothalamus. Upon withdrawal from anabolic/androgenic steroids, this neurobehavioral relationship shifts as hamsters display decreased offensive aggression and increased anxiety correlated with a decrease in anterior hypothalamic vasopressin. This study investigated the hypothesis that alterations in anterior hypothalamic vasopressin neural signaling modulate behavioral shifting between adolescent anabolic/androgenic steroid-induced offensive aggression and anxiety. To test this, adolescent male hamsters were administered anabolic/androgenic steroids and tested for offensive aggression or anxiety following direct pharmacological manipulation of vasopressin V1A receptor signaling within the anterior hypothalamus. Blockade of anterior hypothalamic vasopressin V1A receptor signaling suppressed offensive aggression and enhanced general and social anxiety in hamsters administered anabolic/androgenic steroids during adolescence, effectively reversing the pattern of behavioral response pattern normally observed during the adolescent exposure period. Conversely, activation of anterior hypothalamic vasopressin V1A receptor signaling enhanced offensive aggression in hamsters exposed to anabolic/androgenic steroids during adolescence. Together, these findings suggest that the state of vasopressin neural development and signaling in the anterior hypothalamus plays an important role in behavioral shifting between aggression and anxiety following adolescent exposure to anabolic/androgenic steroids. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Response of adult Necator americanus to some known anthelminthics in hamsters.

    Science.gov (United States)

    Rajasekariah, G R; Deb, B N; Dhage, K R; Bose, S

    1989-06-01

    Adult Necator americanus infection in laboratory hamsters (the hamster-hookworm model) was examined as an anthelminthic screening system. Three reference anthelminthics--pyrantel (PYTL), mebendazole (MBZ) and ivermectin (IVRN)--were used to assess the sensitivity of adult N. americanus and also to investigate the value of the hamster-hookworm model for predicting clinical results. Serial drug dosages were used, and the ED50 was determined from the resulting cure rates. In addition, percentage worm reductions were calculated by reference to the worm burdens in control groups. The results showed that the hamster-hookworm model was able to differentiate anthelminthics on their efficacy. Absolute activity (100% worm reduction) followed treatment with 8 mg kg-1 MBZ, 38-40 mg kg-1 PYTL and 18 mg kg-1 IVRN. Based on ED50 data of PYTL and MBZ, adult N. americanus appeared to be two to five times more sensitive than pre-adult stages. However, with IVRN the reverse appeared true. MBZ appeared to be most active and PYTL least active in terms of curing infected animals, but there were no obvious differences between the rates of worm reductions following single or multiple doses of anthelminthics. It is considered that the hamster-hookworm model will prove of value in identifying and characterizing possible new anthelminthics.

  2. Temperature regulation in the mouse and hamster exposed to microwaves in hot environments

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, C.J.; Long, M.D.; Fehlner, K.S.; Stead, A.G.

    1986-01-01

    Colonic temperature was measured in naive BALB/c mice and golden hamsters immediately following 90-min exposures to 2450-MHz radiofrequency (RF) radiation at an ambient temperature (Ta) of 32.2 or 35 C (dry air). Exposures were performed in a temperature-controlled waveguide that permitted continuous monitoring of the specific absorption rate (SAR) of RF energy. At a Ta of 32.2 C, the threshold SAR for elevating colonic temperature and the SAR resulting in a 1.0 C elevation in colonic temperature were, respectively, 4.3 and 10.0 W/kg for the mouse and 0.69 and 1.9 W/kg for the hamster. At a Ta of 35 C, these values were 0.12 and 5.3 W/kg for the mouse and 0.46 and 1.4 W/kg for the hamster. The SARs required to induce hyperthermia in the mouse and hamster at these relatively warm Ta's are considerably lower than those required at cooler Ta's of 20 to 3 C. Overall, the hamster became hyperthermic at lower SARs than in the mouse. Ta's of 35 C and greater are frequently encountered during heat waves in the summer months.

  3. Thermogenin amount and activity in hamster brown fat mitochondria: effect of cold acclimation

    International Nuclear Information System (INIS)

    Sundin, U.; Moore, G.; Nedergaard, J.; Cannon, B.

    1987-01-01

    To investigate the acclimation process in a hibernator, four different parameters of thermogenin amount and activity were investigated in brown adipose tissue mitochondria from cold-exposed and cold-acclimated Syrian hamsters. Hamsters, which are hibernators, have been considered to be primed for thermogenesis and thus not to show cold-acclimation effects, but here a significant increase in [ 3 H]GDP-binding capacity was observed, and this increase was paralleled by an increase in thermogenin antigen amount, as measured in an enzyme-linked immunosorbent assay. The transient nature of the effect of cold exposure on [ 3 H]GDP binding, characteristically observed with rat mitochondria, was not observed with hamster mitochondria, and the increase in [ 3 H]GDP binding occurred without a change in the dissociation constant. The increase in thermogenin amount was paralleled by an increase both in GDP-sensitive Cl - permeability of the mitochondria and in GDP-sensitive respiration. It was established that it is the maximal activity of thermogenin that is rate limiting for thermogenesis in isolated mitochondria, provided that an optimal substrate is used (such as palmitoyl carnitine). Cold acclimation also increased the total amount of mitochondria in the tissue, leading totally to a sixfold increase in thermogenin content of the hamster. It is concluded that hamsters show the expected physiological, pharmacological, and biochemical signs of cold acclimation

  4. Body temperature circadian rhythm variability corresponds to left ventricular systolic dysfunction in decompensated cardiomyopathic hamsters.

    Science.gov (United States)

    Ahmed, Amany; Gondi, Sreedevi; Cox, Casey; Zheng, Minjuan; Mohammed, Anwarullah; Stupin, Igor V; Wang, Suwei; Vela, Deborah; Brewer, Alan; Elayda, Macarthur A; Buja, L Maximilian; Ward Casscells, S; Wilson, James M

    2011-11-01

    A declining amplitude of body temperature circadian rhythm (BTCR) predicts decompensation or death in cardiomyopathic hamsters. We tested the hypothesis that changes in BTCR amplitude accompany significant changes in left ventricular (LV) size and function. Using intraperitoneal transmitters, we continuously monitored the temperature of 30 male BIO TO-2 Syrian dilated cardiomyopathic hamsters. Cosinor analysis was used to detect significant changes--defined as changes >1 standard deviation from the baseline amplitude for 3 consecutive days--in BTCR amplitude over each hamster's lifespan. The Student t-test was used to compare BTCR variability and LV size and function (as assessed by 2D echocardiography) between baseline and the time that BTCR amplitude declined. All hamsters received 10 mg/kg furosemide daily. At the time of BTCR amplitude decline, functional parameters had changed significantly (P < .0001) from baseline: ejection fraction (0.31 ± 0.09% vs. 0.52 ± 0.08%), LV end-systolic volume (0.11 ± 0.03 vs. 0.05 ± 0.02 cm(3)), and LV end-diastolic volume (0.16 ± 0.04 vs. 0.10 ± 0.03 cm(3)). In decompensated cardiomyopathic hamsters, a decline in BTCR amplitude was associated with progression of heart failure and cardiac decompensation. Variation in BTCR warrants further investigation because of its potential implications for the diagnosis and treatment of cardiovascular disorders. Published by Elsevier Inc.

  5. Effects of aqueous cinnamon extract on chemically-induced carcinoma of hamster cheek pouch mucosa

    Directory of Open Access Journals (Sweden)

    Samah K. Ezzat

    2017-12-01

    Full Text Available This study aimed to investigate the effects of aqueous cinnamon extract (ACE on 7, 12-Dimethylbenz[a]anthracene (DMBA-induced oral carcinogenesis in hamster cheek pouch (HCP mucosa. Sixty male Syrian hamsters were randomly divided into six equal groups. The hamsters of groups I, II and III received no treatment, DMBA and ACE respectively, for 16 weeks. Groups IV and V were handled as group II and concomitantly treated with ACE for the same period and additionally group V received ACE for other 16 weeks after the stoppage of DMBA application. Group VI hamsters were handled as group III and additionally received DMBA for other 16 weeks after the stoppage of ACE supplementation. Hamsters of each group were euthanized according to the experimental schedule. The buccal pouches were and prepared for H&E stain, PAS reagent, CD3 and PDGF immunohistochemical reactivity. All groups showed dysplastic changes with varying degrees except groups I and III. Deep invasive carcinomas were recorded in 90% of the samples of group II, 60% of group IV, 50% of group V and 40% of group VI. From the previous results, it can be concluded that ACE has the potentiality preventing oral cancer initiation better than inhibiting oral cancer progression.

  6. When Your Child Needs a Kidney Transplant

    Science.gov (United States)

    ... new (donor) kidney in the body dialysis , a therapeutic process that does the work of the kidneys ... Test: Comprehensive Metabolic Panel (CMP) Urine Test: Calcium Ultrasound: Renal (Kidneys, Ureters, Bladder) Word! Kidney Chronic Kidney ...

  7. Babies or No Babies: Communicating with Feminine Bodies in Mom Lit

    Directory of Open Access Journals (Sweden)

    Handojo P.F.

    2016-01-01

    Full Text Available Mom-Lit, or Mommy Literature, can be seen as a form of challenging the feminine body’s ideals and motherhood ideology. The article studies how the feminine bodies are represented in three Mom Lit: Baby Proof by Emily Giffin, Shopaholic and Baby by Sophie Kinsella, and Confessions of A Bad Mother by Stephanie Calman. The way the women describe different bodily experiences prompts questions and challenges to the ideal feminine body and womanhood, which are associated with motherhood. Using the review of Motherhood Ideology and the concept of Silent Body, this article takes a closer look on how the women in Mom Lit think and talk about their bodies. The analysis shows that Mom Lit presents silent body to relate with the childfree choice and offers different maternal body experience that is in contrast with the feminine body ideals. In the end, it can be concluded that Mom Lit constructs a new site of women’s liberation by being receptive and communicative to the body.

  8. Different palm oil preparations reduce plasma cholesterol concentrations and aortic cholesterol accumulation compared to coconut oil in hypercholesterolemic hamsters.

    Science.gov (United States)

    Wilson, Thomas A; Nicolosi, Robert J; Kotyla, Timothy; Sundram, Kalyana; Kritchevsky, David

    2005-10-01

    Several studies have reported on the effect of refined, bleached and deodorized palm oil (RBD-PO) incorporation into the diet on blood cholesterol concentrations and on the development of atherosclerosis. However, very little work has been reported on the influence of red palm oil (RPO), which is higher in carotenoid and tocopherol content than RBD-PO. Thus, we studied the influence of RPO, RBD-PO and a RBD-PO plus red palm oil extract (reconstituted RBD-PO) on plasma cholesterol concentrations and aortic accumulation vs. hamsters fed coconut oil. Forty-eight F1B Golden Syrian hamsters (Mesocricetus auratus) (BioBreeders, Watertown, MA) were group housed (three/cage) in hanging polystyrene cages with bedding in an air-conditioned facility maintained on a 12-h light/dark cycle. The hamsters were fed a chow-based hypercholesterolemic diet (HCD) containing 10% coconut oil and 0.1% cholesterol for 2 weeks at which time they were bled after an overnight fast and segregated into four groups of 12 with similar plasma cholesterol concentrations. Group 1 continued on the HCD, Group 2 was fed the HCD containing 10% RPO in place of coconut oil, Group 3 was fed the HCD containing 10% RBD-PO in place of coconut oil and Group 4 was fed the HCD with 10% reconstituted RBD-PO for an additional 10 weeks. Plasma total cholesterol (TC) and non-high-density lipoprotein-cholesterol (HDL-C) (very low- and low-density lipoprotein) concentrations were significantly lower in the hamsters fed the RPO (-42% and -48%), RBD-PO (-32% and -36%) and the reconstituted RBD-PO (-37% and -41%) compared to the coconut oil-fed hamsters. Plasma HDL-C concentrations were significantly higher by 14% and 31% in hamsters fed the RBD-PO and RPO compared to the coconut oil-fed hamsters. Plasma triglyceride (TG) concentrations were significantly lower in hamsters fed RBD-PO (-32%) and the reconstituted RBD-PO (-31%) compared to the coconut oil-fed hamsters. The plasma gamma-tocopherol concentrations were higher

  9. Should we maintain baby hatches in our society?

    Directory of Open Access Journals (Sweden)

    Asai Atsushi

    2013-02-01

    Full Text Available Abstract Background A baby hatch called the “Stork’s Cradle” has been in place at Jikei Hospital in Kumamoto City, Japan, since May 10, 2007. Babyklappes were first established in Germany in 2000, and there are currently more than 90 locations. Attitudes regarding baby hatches are divided in Japan and neither opinions for nor against baby hatches have thus far been overwhelming. To consider the appropriateness of baby hatches, we present and examine the validity of each major objection to establishing baby hatches. Discussion There are various objections to baby hatches as follows: It violates a child’s right to know the identity of his or her biological parents by allowing anonymous birth; it neglects fulfillment of the biological parents’ basic obligation to raise their child and its very availability induces abandonment of infants; some people abuse it for very selfish reasons; it cannot save babies’ lives; the rights of one parent can be ignored if the other surrenders a child without his or her consent; it puts a baby in medical jeopardy; and it has no clear legal basis. The authors would argue that there are many plausible refutations for each objection mainly based on priority of child’s right to life, pregnant women’s vulnerability and necessity of anonymity, social responsibility to protect and raise children, differences between dropping a child off at a baby hatch and child neglect, limited function of social childcare center, inevitability of abuse by a minority of people, necessary distinction between outcomes that occur only because baby hatches exist and those that occur regardless of their existence, important local direct and upmost measures for women in trouble, and difference between ambiguous legality and illegality. Summary We argue that a certain number of baby hatches should continue to be established as a last resort, in a form that can maintain anonymity if the parent dropping the child off so desires. It

  10. Planning sex of baby -- the Barthakur method.

    Science.gov (United States)

    Koshy, L M

    1994-07-30

    The sex of any given human zygote is dependent upon when the ovum is placed in the fallopian tube. Dr. Inderjit K. Barthakur's has developed a way for heterosexual couples to conceive either male or female children depending upon the timing of their coitus. To have a baby of preferred gender, a couple should have coitus in accordance with the advice of a well-informed instructor who can determine the exact date of rupture of the Graafian follicle with ultrasound scanning. The method requires these preconditions: keeping a temperature chart from 3-4 months before the month in which the pregnancy is planned, abstaining from sex during that particular month until the time advised by the instructor, and having daily ultrasound scans after the 9th day of the menstrual cycle to ensure the highest degree of accuracy in identifying the best time for intercourse. Accurate sex determination of the fetus has occurred in 71 of 72 cases managed by the four physicians who practice this method in India. A more simple alternative which is easily communicable to the poor and uneducated has also been developed by the doctors, but it is only 80% successful. These high rates of success have generated widespread international interest, but the ICMR, the Health Ministry, and others have turned down appeals to support studies of the method because they do not want to encourage potential discrimination against females. Abortion, however, which is often gender-biased, is legal. Dr. Barthakur and her colleagues ensure that the couples taken for instruction should desire a child of the sex opposite to the existing one and no tests are conducted after conception to confirm the sex of the fetus. Under current funding constraints, all expenses for the procedures are met jointly by the involved doctors and couples who are well-off enough to go in for repeated ultrasounds.

  11. η Carinae Baby Homunculus uncovered by ALMA

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, Zulema; Beaklini, Pedro P. B. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, R. do Matão 1226, Cidade Universitária, CEP 05508-900 São Paulo, SP (Brazil); Falceta-Gonçalves, Diego, E-mail: zulema.abraham@iag.usp.br [Escola de Artes, Ciências e Humanidades, Universidade de São Paulo, R. Arlindo Bettio 1000, 03828-000 São Paulo, SP (Brazil)

    2014-08-20

    We report observations of η Carinae obtained with ALMA in the continuum of 100, 230, 280, and 660 GHz in 2012 November, with a resolution that varied from 2.''88 to 0.''45 for the lower and higher frequencies, respectively. The source is not resolved, even at the highest frequency; its spectrum is characteristic of thermal bremsstrahlung of a compact source, but different from the spectrum of optically thin wind. The recombination lines H42α, He42α, H40α, He40α, H50β, H28α, He28α, H21α, and He21α were also detected, and their intensities reveal non-local thermodynamic equilibrium effects. We found that the line profiles could only be fit by an expanding shell of dense and ionized gas, which produces a slow shock in the surroundings of η Carinae. Combined with fittings to the continuum, we were able to constrain the shell size, radius, density, temperature, and velocity. The detection of the He recombination lines is compatible with the high-temperature gas and requires a high-energy ionizing photon flux, which must be provided by the companion star. The mass-loss rate and wind velocity, necessary to explain the formation of the shell, are compatible with an luminous blue variable eruption. The position, velocity, and physical parameters of the shell coincide with those of the Weigelt blobs. The dynamics found for the expanding shell correspond to matter ejected by η Carinae in 1941 in an event similar to that which formed the Little Homunculus; for that reason, we called the new ejecta the 'Baby Homunculus'.

  12. Mindful with Your Baby : Feasibility, Acceptability, and Effects of a Mindful Parenting Group Training for Mothers and Their Babies in a Mental Health Context

    NARCIS (Netherlands)

    Potharst, E.S.; Aktar, E.; Rexwinkel, M.; Rigterink, M.; Bögels, S.M.

    2017-01-01

    Many mothers experience difficulties after the birth of a baby. Mindful parenting may have benefits for mothers and babies, because it can help mothers regulate stress, and be more attentive towards themselves and their babies, which may have positive effects on their responsivity. This study

  13. Butter blend containing fish oil improves the level of n-3 fatty acids in biological tissues of hamster

    DEFF Research Database (Denmark)

    Porsgaard, Trine; Overgaard, Jesper; Krogh, Anne Louise

    2007-01-01

    Syrian hamsters received hamster feed blended with one of the three butter products. After 6 weeks of feeding, the fatty acid compositions of plasma, erythrocytes, liver, brain, and visceral fat were determined. The intake of butter product with fish oil resulted in a higher level of n-3 PUFA in plasma...

  14. Vasopressin immunoreactivity and release in the suprachiasmatic nucleus of wild-type and tau mutant Syrian hamsters

    NARCIS (Netherlands)

    Van der Zee, EA; Oklejewicz, M; Jansen, K; Daan, S; Gerkema, MP

    2002-01-01

    Despite the prominent role of the Syrian hamster (Mesocricetus auratus) in studies of circadian rhythms, there are no data available on the temporal dynamics of the neuropeptide vasopressin (AVP), a major output system of the suprachiasmatic nucleus (SCN). We studied the hamster SCN-AVP system in

  15. PENGARUH PEMBERIAN EKSTRAK KUNYIT PADA ANAK BABI YANG MENDERITA COLIBACILLOSIS

    Directory of Open Access Journals (Sweden)

    I NENGAH KERTA BESUNG

    2012-09-01

    Full Text Available ABSTRAK Kolibasilosis adalah salah satu penyakit pada anak babi yang disebabkan oleh Escherichia coli (E.coli dan umumnya penyakit tersebut diobati dengan antibiotika. Penelitian ini bertujuan untuk mendapatkan informasi pengaruh kunyit sebagai obat alternatif untuk mengobati kejadian kolibasilosis pada anak babi. Dua belas ekor anak babi yang menderita kolibasilosis dikelompokkan ke dalam tiga kelompok yakni kelompok pertama adalah anak babi sebagai kontrol yakni tidak diberikan ekstrak kunyit maupun sulfonamida. Kelompok kedua anak babi diberikan ekstrak kunyit, sedangkan kelompok ketiga anak babi diobati dengan sulfonamida. Data berupa kejadian diare dan total bakteri E. coli dianalisis dengan analisis varian. Pengaruh pemberian kunyit dan pengobatan dengan sulfonamida nampak pada hari kelima setelah perlakuan, yakni berupa penurunan kejadian diare dan pengurangan total bakteri E.coli. Hasil penelitian menunjukkkan bahwa ekstrak kunyit sangat potensial dapat dipakai sebagai obat alternatif dalam pengobatan penyakit kolibasilosis pada anak babi. THE EFFECT OF TURMERIC (Curcuma longa ON PIGLETS WITH COLIBACILLOSIS ABSTRACT Colibacillosis is one of diseases in piglets coused by Eschericia coli (E.coli, and commonly antibiotica therapy to used preventively that diseases. The present study was conducted to observe that effect of turmeric (Curcuma longa, as a alternative drugs on therapy of collibacillosis. Twelve of piglets with colibacillosis diseases were devided in to three groups, each group consisted of four piglets. First group was the negative control group without treatment of sulphonamides and turmeric too, the second group was the turmeric extract treatment and the last group was the colibacillosis piglets treated with sulphonamides. Analisis of variance was to analysed of data from diarrhea occurrence and a total of E. coli bacteria. Effect of turmeric and sulphonamides on colibacillosis of all piglets was detected at fifth days, with

  16. Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

    DEFF Research Database (Denmark)

    Lewis, Nathan E; Liu, Xin; Li, Yuxiang

    2013-01-01

    Chinese hamster ovary (CHO) cells, first isolated in 1957, are the preferred production host for many therapeutic proteins. Although genetic heterogeneity among CHO cell lines has been well documented, a systematic, nucleotide-resolution characterization of their genotypic differences has been...... stymied by the lack of a unifying genomic resource for CHO cells. Here we report a 2.4-Gb draft genome sequence of a female Chinese hamster, Cricetulus griseus, harboring 24,044 genes. We also resequenced and analyzed the genomes of six CHO cell lines from the CHO-K1, DG44 and CHO-S lineages....... This analysis identified hamster genes missing in different CHO cell lines, and detected >3.7 million single-nucleotide polymorphisms (SNPs), 551,240 indels and 7,063 copy number variations. Many mutations are located in genes with functions relevant to bioprocessing, such as apoptosis. The details...

  17. Peripheral kisspeptin reverses short photoperiod-induced gonadal regression in Syrian hamsters by promoting GNRH release

    DEFF Research Database (Denmark)

    Ansel, L; Bentsen, A H; Ancel, C

    2011-01-01

    In seasonal breeders, reproduction is synchronised by day length via the pineal hormone melatonin. In short winter days (short day, SD), the Syrian hamster displays a complete gonadal atrophy together with a marked reduction in expression of kisspeptins (Kp), a family of potent hypothalamic...... stimulators of GNRH neurons. Both central and peripheral acute injections of Kp have been reported to activate the gonadotropic axis in mammals. The aim of this study was to determine if and how peripheral administration of Kp54 could restore gonadal function in photo-inhibited hamsters. Testicular activity...... of hamsters kept in SD was reactivated by two daily i.p. injections of Kp54 but not by chronic subcutaneous delivery of the same peptide via mini-pumps. Acute i.p. injection of Kp54-induced FOS (c-Fos) expression in a large number of GNRH neurons and pituitary gonadotrophs together with a strong increase...

  18. Blood Vessel Normalization in the Hamster Oral Cancer Model for Experimental Cancer Therapy Studies

    Energy Technology Data Exchange (ETDEWEB)

    Ana J. Molinari; Romina F. Aromando; Maria E. Itoiz; Marcela A. Garabalino; Andrea Monti Hughes; Elisa M. Heber; Emiliano C. C. Pozzi; David W. Nigg; Veronica A. Trivillin; Amanda E. Schwint

    2012-07-01

    Normalization of tumor blood vessels improves drug and oxygen delivery to cancer cells. The aim of this study was to develop a technique to normalize blood vessels in the hamster cheek pouch model of oral cancer. Materials and Methods: Tumor-bearing hamsters were treated with thalidomide and were compared with controls. Results: Twenty eight hours after treatment with thalidomide, the blood vessels of premalignant tissue observable in vivo became narrower and less tortuous than those of controls; Evans Blue Dye extravasation in tumor was significantly reduced (indicating a reduction in aberrant tumor vascular hyperpermeability that compromises blood flow), and tumor blood vessel morphology in histological sections, labeled for Factor VIII, revealed a significant reduction in compressive forces. These findings indicated blood vessel normalization with a window of 48 h. Conclusion: The technique developed herein has rendered the hamster oral cancer model amenable to research, with the potential benefit of vascular normalization in head and neck cancer therapy.

  19. Healing acceleration in hamsters of oral mucositis induced by 5-fluorouracil with topical Calendula officinalis.

    Science.gov (United States)

    Tanideh, Nader; Tavakoli, Parisa; Saghiri, Mohammad Ali; Garcia-Godoy, Franklin; Amanat, Dariush; Tadbir, Azadeh Andisheh; Samani, Soleiman Mohammadi; Tamadon, Amin

    2013-03-01

    This study assessed the potential of topical Calendula officinalis extract on the healing of oral mucositis induced by 5-fluorouracil (5-FU) in hamsters. Oral mucositis was induced in 60 male hamsters by 5-FU (60 mg/kg) on days 0, 5, and 10 of the study. The cheek pouch was scratched with a sterile needle on days 1 and 2. On days 12-17, 5% and 10% C. officinalis gel and gel base groups were treated and then compared with a control group. Macroscopic and microscopic scores and weights were evaluated. Microscopic and macroscopic scores of mucositis were lower in the 5% and 10% C. officinalis gel groups than in the gel base and control groups (P Calendula officinalis extract accelerated the healing of oral mucositis in hamsters. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Efficacy of minocycline and tigecycline in a hamster model of leptospirosis.

    Science.gov (United States)

    Tully, Charla C; Hinkle, Mary K; McCall, Suzanne; Griffith, Matthew E; Murray, Clinton K; Hospenthal, Duane R

    2011-12-01

    Leptospirosis is a widespread zoonotic infection characterized by acute febrile illness. Severely ill patients may require empiric treatment with broad-spectrum antibiotics prior to definitive diagnosis. We evaluated the efficacy of minocycline and tigecycline against leptospirosis in a hamster model. Hamsters were treated with either minocycline (5, 10, or 25 mg/kg per day) or tigecycline (5, 10, or 25 mg/kg per day) for 5 days. Controls included untreated animals and doxycycline-treated animals (5 mg/kg per day). Nine days after infection, all untreated animals were dead. All treated hamsters survived to the end of study (day 21). Study groups showed significantly improved survival compared to the untreated group (P < .01). Minocycline and tigecycline showed survival benefit comparable to the standard treatment, doxycycline. In the absence of doxycycline, minocycline may be considered as an alternative, while tigecycline may be useful in the management of severely ill patients prior to a definitive diagnosis. Published by Elsevier Inc.

  1. Blood leukocyte and spleen lymphocyte immune response of spleen lymphocytes and whole blood leukocytes of hamsters

    Energy Technology Data Exchange (ETDEWEB)

    Peters, B.A.; Sothmann, M.; Wehrenberg, W.B. (Univ. of Wisconsin, Milwaukee (USA))

    1989-01-01

    This study was designed to evaluate the effects of chronic physical activity on the immune response of spleen lymphocytes and whole blood leukocytes of hamsters. Animals were kept sedentary or allowed to exercise spontaneously on running wheels for eight weeks. Physically active animals averaged 12 kilometers per day. The immune response of spleen lymphocytes whole blood leukocytes was evaluated by {sup 3}H-thymidine incorporation in response to Concanavalin A or lipopolysaccharide. There was no treatment effect between physically active and sedentary hamster in response of spleen lymphocytes. The immune response of whole blood leukocytes to these mitogens was significantly greater in physically active vs. sedentary hamsters. These results demonstrate that chronic physical activity has the capacity to modulate immunoresponses.

  2. Zika virus infection of adult and fetal STAT2 knock-out hamsters.

    Science.gov (United States)

    Siddharthan, Venkatraman; Van Wettere, Arnaud J; Li, Rong; Miao, Jinxin; Wang, Zhongde; Morrey, John D; Julander, Justin G

    2017-07-01

    Zika virus (ZIKV) infection was investigated in adult and fetal STAT2 knock-out (KO) hamsters. Subcutaneous injection of ZIKV of adults resulted in morbidity, mortality, and infection of the uterus, placenta, brain, spinal cord, and testicles, thus providing an opportunity to evaluate congenital ZIKV infection in a second rodent species besides mice. ZIKV-infected cells with morphologies of Sertoli cells and spermatogonia were observed in the testes, which may have implications for sexual transmission and male sterility. Neonates exposed as fetuses to ZIKV at 8 days post-coitus were not smaller than controls. Nevertheless, infectious virus and ZIKV RNA was detected in some, but not all, placentas and fetal brains of KO hamsters. STAT2 KO hamsters may be useful for addressing sexual transmission, pathogenesis, routes of fetal infection, and neurological disease outcomes, and may also be used in antiviral or vaccine studies to identify intervention strategies. Copyright © 2017. Published by Elsevier Inc.

  3. DIP and DIP + 2 as glutathione oxidants and radiation sensitizers in cultured Chinese hamster cells

    International Nuclear Information System (INIS)

    Harris, J.W.; Power, J.A.; Kosower, N.S.; Kosower, E.M.

    1975-01-01

    Two diamide analogues, diazene dicarboxylic acid bis (N'-methyl-piperazide) or DIP, and its bis-N'-methyl iodide salt, or DIP + 2, were tested for their ability to penetrate cultured Chinese hamster cells and oxidize intracellular glutathione. DIP penetrated the cells at a reasonable rate at 18 0 C, 160 nmoles being required to oxidize the endogenous glutathione of 2 x 10 6 cells, but it penetrated very slowly at 0 0 C. DIP + 2 did not effectively oxidize glutathione in Chinese hamster cells, possibly because it did not enter the cels. DIP became toxic after about 10 min of exposure, but its toxicity could be moderated by using anoxic conditions. DIP, but not DIP + 2, sensitized anoxic Chinese hamster cells to X-radiation by a factor of 1.5, an effect that was due entirely to removal of the shoulder from the survival curve. (author)

  4. Multistep change in epidermal growth factor receptors during spontaneous neoplastic progression in Chinese hamster embryo fibroblasts

    International Nuclear Information System (INIS)

    Wakshull, E.; Kraemer, P.M.; Wharton, W.

    1985-01-01

    Whole Chinese hamster embryo lineages have been shown to undergo multistep spontaneous neoplastic progression during serial passage in culture. The authors have studied the binding, internalization, and degradation of 125 I-labeled epidermal growth factor at four different stages of transformation. The whole Chinese hamster embryo cells lost cell surface epidermal growth factor receptors gradually during the course of neoplastic progression until only 10% of the receptor number present in the early-passage cells (precrisis) were retained in the late-passage cells (tumorigenic). No differences in internalization rates, chloroquine sensitivity, or ability to degrade hormone between the various passage levels were seen. No evidence for the presence in conditioned medium of transforming growth factors which might mask or down-regulate epidermal growth factor receptor was obtained. These results suggest that a reduction in cell surface epidermal growth factor receptor might be an early event during spontaneous transformation in whole Chinese hamster embryo cells

  5. Memory for individual scent in hamsters (Mesocricetus auratus) as assessed by habituation methods.

    Science.gov (United States)

    Johnston, R E

    1993-06-01

    The memory of hamsters (Mesocricetus auratus) for the flank scent of other male hamsters was investigated in a series of habituation experiments. In 2 types of habituation tasks (Experiments 1 and 2), male hamsters habituated to the flank scent of 1 male and then increased their level of investigation to that of a novel male; similar results were obtained when the intervals between trials ranged from 1 s to 2 days. When the test trial was 10 or 21 days after habituation (Experiment 3), males discriminated between familiar and novel flank scents at 10 days but not at 21 days. The results demonstrate recognition of familiar and unfamiliar individual odors and excellent memory for these differences. Habituation techniques yield extremely robust results and may be useful for investigations of other aspects of individual signatures.

  6. Alterations of male sexual behavior by learned aversions to hamster vaginal secretion.

    Science.gov (United States)

    Johnston, R E; Zahorik, D M; Immler, K; Zakon, H

    1978-02-01

    Male hamsters poisoned after their first adult exposure to the vaginal secretion of female hamsters became hesitant to approach and ingest the secretion. The same aversion-training procedure also altered the responses of males to estrous females, changing the latency, frequency, and duration of a variety of behaviors that are commonly taken as indexes of sexual attraction or arousal and of copulatory performance. The effects suggest that the aversions to vaginal secretion alter the perceived meaning of the secretion for male hamsters, and analysis of the correlations between various measures of sexual arousal and performance support the hypothesis that separate mechanisms underlie the effects of the secretion on appetitive and consummatory sexual behavior.

  7. Stressors, including social conflict, decrease plasma prolactin in male golden hamsters.

    Science.gov (United States)

    Huhman, K L; Mougey, E H; Moore, T O; Meyerhoff, J L

    1995-12-01

    Following exposure to a stressor, plasma prolactin (PRL) rises in most species. The purpose of the present study was to examine the effect of social conflict or of footshock stress on PRL responsiveness in male Syrian hamsters. Contrary to expectations, PRL was significantly lower in subordinate hamsters than in their dominant opponents or in controls following one, five, or nine exposures to social conflict. Similarly, PRL was reduced in hamsters subjected to a mild footshock stressor. By contrast, adrenocorticotropin, another stress-responsive hormone, was elevated following exposure to each of these stressors. We also demonstrate that PRL release is inhibited by dopamine as it is in other species by showing that there is a dose-dependent increase in PRL release following treatment with the dopamine receptor blocker, domperidone.

  8. Adapting to alcohol: Dwarf hamster (Phodopus campbelli) ethanol consumption, sensitivity, and hoard fermentation.

    Science.gov (United States)

    Lupfer, Gwen; Murphy, Eric S; Merculieff, Zoe; Radcliffe, Kori; Duddleston, Khrystyne N

    2015-06-01

    Ethanol consumption and sensitivity in many species are influenced by the frequency with which ethanol is encountered in their niches. In Experiment 1, dwarf hamsters (Phodopus campbelli) with ad libitum access to food and water consumed high amounts of unsweetened alcohol solutions. Their consumption of 15%, but not 30%, ethanol was reduced when they were fed a high-fat diet; a high carbohydrate diet did not affect ethanol consumption. In Experiment 2, intraperitoneal injections of ethanol caused significant dose-related motor impairment. Much larger doses administered orally, however, had no effect. In Experiment 3, ryegrass seeds, a common food source for wild dwarf hamsters, supported ethanol fermentation. Results of these experiments suggest that dwarf hamsters may have adapted to consume foods in which ethanol production naturally occurs. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver.

    Science.gov (United States)

    Matsuzaki, Yasushi; Bouscarel, Bernard; Ikegami, Tadashi; Honda, Akira; Doy, Mikio; Ceryak, Susan; Fukushima, Sugano; Yoshida, Shigemasa; Shoda, Junichi; Tanaka, Naomi

    2002-11-20

    The aim of this study was to explore the regulation of serum cholic acid (CA)/chenodeoxycholic acid (CDCA) ratio in cholestatic hamster induced by ligation of the common bile duct for 48 h. The serum concentration of total bile acids and CA/CDCA ratio were significantly elevated, and the serum proportion of unconjugated bile acids to total bile acids was reduced in the cholestatic hamster similar to that in patients with obstructive jaundice. The hepatic CA/CDCA ratio increased from 3.6 to 11.0 (PCYP27A1 is, at least in part, responsible for the relative decreased production of CDCA and increased CA/CDCA ratio in the liver, bile and serum of cholestatic hamsters.

  10. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters

    DEFF Research Database (Denmark)

    Ansel, L; Bolborea, M; Bentsen, A H

    2010-01-01

    In seasonal breeders, reproduction is synchronized to seasons by day length via the pineal hormone melatonin. Recently, we have demonstrated that Kiss1, a key activator of the reproductive function, is down-regulated in sexually inactive hamsters maintained in inhibitory short days (SDs...... differentially regulate Kiss1 expression in the ARC and the AVPV. Kiss1 expression was examined by in situ hybridization in both male and female hamsters kept in various experimental conditions, and we observed that 1) SD exposure markedly reduced Kiss1 expression in the ARC and AVPV of male and female hamsters...... as compared to LD animals, 2) sex steroid treatment in SD-adapted male and female hamsters increased the number of Kiss1 neurons in the AVPV but decreased it in the ARC, 3) melatonin administration to LD-adapted hamsters decreased Kiss1 mRNA level in both the AVPV and the ARC in intact animals, whereas...

  11. Andrographolide Ameliorates Beta-Naphthoflavone-Induced CYP1A Enzyme Activity and Lipid Peroxidation in Hamsters with Acute Opisthorchiasis.

    Science.gov (United States)

    Udomsuk, Latiporn; Chatuphonprasert, Waranya; Jarukamjorn, Kanokwan; Sithithaworn, Paiboon

    2016-01-01

    Opisthorchis viverrini (OV) infection generates oxidative stress/free radicals and is considered as a primary cause ofcholangiocarcinoma since it primarily triggers sclerosing cholangitis. In this study, the impacts of andrographolide on acute opisthorchaisis in β-naphthoflavone (BNF)-exposed hamsters were investigated. Ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase (MROD) activities and Thiobarbituric acid reaction substances (TBARS) assay of andrographolide in acute opisthorchiasis in the BNF-exposed hamsters were assessed. The results showed that andrographolide ameliorated the hepatic CYP1A1 and CYP1A2 activities by decreases of the specific enzymatic reactions of EROD and MROD, respectively, in the BNF-exposed hamsters. Moreover, andrographolide lowered the formation of malondialdehyde in the livers and brains of the hamsters. These observations revealed the promising chemo-protective and antioxidant activities of andrographolide via suppression of the specific EROD and MROD reactions and lipid peroxidation against acute opisthorchiasis in the BNF-exposed hamsters.

  12. A longitudinal study on BIO14.6 hamsters with dilated cardiomyopathy: micro-echocardiographic evaluation

    Directory of Open Access Journals (Sweden)

    Belfiore Maria

    2011-12-01

    Full Text Available Abstract Background In recent years, several new technologies for small-animal imaging have been developed. In particular, the use of ultrasound in animal imaging has focused on the investigation of accessible biological structures such as the heart, of which it provides a morphological and functional assessment. The purpose of this study was to investigate the role of micro-ultrasonography (μ-US in a longitudinal study on BIO14.6 cardiomyopathic hamsters treated with gene therapy. Methods Thirty hamsters were divided into three groups (n = 10: Group I, untreated BIO 14.6 hamsters; Group II, BIO 14.6 hamsters treated with gene therapy; Group III, untreated wild type (WT hamsters. All hamsters underwent serial μ-US sessions and were sacrificed at predetermined time points. Results μ-US revealed: in Group I, progressive dilation of the left ventricle with a change in heart morphology from an elliptical to a more spherical shape, altered configuration of the mitral valve and subvalvular apparatus, and severe reduction in ejection fraction; in Group II, mild decrease in contractile function and ejection fraction; in Group III, normal cardiac chamber morphology and function. There was a negative correlation between the percentage of fibrosis observed at histology and the ejection fraction obtained on μ-echocardiography (Spearman r: -0.839; p Conclusions Although histological examination remains indispensable for a conclusive diagnosis, high-frequency μ-echocardiography, thanks to the high spatial and contrast resolution, can be considered sufficient for monitoring therapeutic efficacy and/or the progression of dilated cardiomyopathy, providing an alternative tool for repeatable and noninvasive evaluation.

  13. The influence of sex and diet on the characteristics of hibernation in Syrian hamsters.

    Science.gov (United States)

    Trefna, Marie; Goris, Maaike; Thissen, Cynthia M C; Reitsema, Vera A; Bruintjes, Jojanneke J; de Vrij, Edwin L; Bouma, Hjalmar R; Boerema, Ate S; Henning, Robert H

    2017-07-01

    Research on deep hibernators almost exclusively uses species captured from the wild or from local breeding. An exception is Syrian hamster (Mesocricetus auratus), the only standard laboratory animal showing deep hibernation. In deep hibernators, several factors influence hibernation quality, including body mass, sex and diet. We examined hibernation quality in commercially obtained Syrian hamsters in relation to body mass, sex and a diet enriched in polyunsaturated fatty acids. Animals (M/F:30/30, 12 weeks of age) were obtained from Harlan (IN, USA) and individually housed at 21 °C and L:D 14:10 until 20 weeks of age, followed by L:D 8:16 until 27 weeks. Then conditions were changed to 5 °C and L:D 0:24 for 9 weeks to induce hibernation. Movement was continuously monitored with passive infrared detectors. Hamsters were randomized to control diet or a diet 3× enriched in linoleic acid from 16 weeks of age. Hamsters showed a high rate of premature death (n = 24, 40%), both in animals that did and did not initiate torpor, which was unrelated to body weight, sex and diet. Time to death (31.7 ± 3.1 days, n = 12) or time to first torpor bout (36.6 ± 1.6 days, n = 12) was similar in prematurely deceased hamsters. Timing of induction of hibernation and duration of torpor and arousal was unaffected by body weight, sex or diet. Thus, commercially obtained Syrian hamsters subjected to winter conditions showed poor survival, irrespective of body weight, sex and diet. These factors also did not affect hibernation parameters. Possibly, long-term commercial breeding from a confined genetic background has selected against the hibernation trait.

  14. Acute Kidney Failure

    Science.gov (United States)

    ... breath Acute kidney failure Symptoms & causes Diagnosis & treatment Advertisement Mayo Clinic does not endorse companies or products. ... a Job Site Map About This Site Twitter Facebook Google YouTube Pinterest Mayo Clinic is a not- ...

  15. Kidney Cancer Risk Questionnaire

    Science.gov (United States)

    ... NCI Cancer Information A to Z Treatment Roles Cancer Types Bladder Brain/Spine Breast Cervical Colorectal Esophageal Gallbladder Head/Neck Kidney Leukemia Liver Lung Lymphoma Multiple Myeloma Ovarian Pancreatic ...

  16. Images in kidney trauma

    International Nuclear Information System (INIS)

    Rodriguez, Jose Luis; Rodriguez, Sonia Pilar; Manzano, Ana Cristina

    2007-01-01

    A case of a 3 years old female patient, who suffered blunt lumbar trauma (horse kick) with secondary kidney trauma, is reported. Imaging findings are described. Renal trauma classification and imaging findings are reviewed

  17. World Kidney Day 2012

    African Journals Online (AJOL)

    2012-02-01

    stage renal disease (ESRD)) worldwide. What was an experimental, risky and .... of deceased and living donor kidney transplants in World Health Organization member states in 2010, correlated with Human Development Index.

  18. Living kidney donation

    DEFF Research Database (Denmark)

    Agerskov, Hanne; Bistrup, Claus; Ludvigsen, Mette Spliid

    2014-01-01

    BACKGROUND: When possible, renal transplantation is the treatment of choice for patients with end-stage kidney disease. Technological developments in immunology have made it possible to perform kidney transplants between donors and recipients despite antibodies against the donor organ. This allows...... for a wider range of relationships between recipient and donor. We investigated experiences of, and reflections on, kidney donation among genetic and non-genetic living donors before first consultation at the transplant centre. OBJECTIVE: The aim was to investigate early experiences in the process of becoming...... a living kidney donor (LKD). MATERIALS AND METHODS: The study was conducted within a phenomenological-hermeneutic theoretical framework. Data were generated through semi-structured interviews with 18 potential donors. Data were interpreted and discussed in accordance with the Ricoeur's text interpretation...

  19. Chronic Kidney Diseases

    Science.gov (United States)

    ... changes, vitamins, minerals, and medications to help with growth and to prevent bone disease. Sometimes unhealthy kidneys have problems producing a hormone that helps make red blood cells, the cells ...

  20. Elk3 from hamster-a ternary complex factor with strong transcriptional repressor activity

    DEFF Research Database (Denmark)

    Hjortoe, G.M.; Weilguny, D.; Willumsen, Berthe Marie

    2005-01-01

    the transcription of genes that are activated during entry into G1. We have isolated the Cricetulus griseus Elk3 gene from the Chinese hamster ovary (CHO) cell line and investigated the transcriptional potential of this factor. Transient transfections revealed that, in addition to its regulation of the c......-fos promoter, Elk3 from CHO cells seems to inhibit other promoters controlling expression of proteins involved in G1/S phase progression; Cyclin D1 and DHFR. As has been described for the Elk3 homologs Net (Mouse) and Sap-2 (Human), the results of the present study further indicate that hamster Elk3...