WorldWideScience

Sample records for azm transition issues

  1. Ibn Ḥazm on Homosexuality. A case-study of Ẓāhirī legal Methodology

    Directory of Open Access Journals (Sweden)

    Adang, Camilla

    2003-06-01

    Full Text Available This article discusses the views of the teologian and legal scholar Ibn Ḥazm of Cordoba (d. 456/1064 on homosexuality. Although reference is made to his literary work Ṭawq al-ḥamāma, which is rich in anecdotes on homoerotic attraction, the article focuses on Ibn Ḥazm's multivolume legal tract Kitāb al-Muḥallā, a work written from a Ẓāhirī, or literalist perspective. A step-by-step analysis of Ibn Hazm's legal reasoning on homosexuality, both male (liwāṭ and female (siḥāq is provided, and comparisons with the views of other jurist, especially Mālikis, are made. Unlike his Mālikī contemporaries, Ibn Ḥazm holds that homosexuality is not to be equated with fomication (zinā, which incurs the death penalty. Instead, he advocates a relatively mild punishment of up to ten lashes for homosexual practices, based upon his idiosyncratic interpretation of the revealed sources which is illustrated here. Although Ibn Ḥazm is believed by some modem authors to have had homosexual leanings himself, he categorically condemns sexual contacts between members of the same sex as immoral and sinful, and believes that homosexuals should be reformed.

    Este artículo discute las opiniones de Ibn Ḥazm de Córdoba (m. 456/1064 jurista y teólogo, acerca de la homosexualidad. Aunque se hace referencia a su obra literaria Ṭawq al-ḥamāma, rica en anécdotas sobre atracción homoerótica, el artículo se centra en su voluminosa obra legal zahirí Kitāb al-Muḥallā y analiza el razonamiento legal de Ibn Ḥazm sobre la homosexualidad tanto masculina (liwāf como femenina (siḥāq comparándola con la de otros juristas, en particular, malikíes. A diferencia de sus contemporáneos malikíes, Ibn Hazm mantiene que la homosexualidad no debe equipararse a la fornicación (zinā que incurre en la pena de muerte. Por el contrario, aboga por el relativamente suave

  2. Ibn Ḥazm on Homosexuality. A case-study of Ẓāhirī legal Methodology

    OpenAIRE

    Adang, Camilla

    2003-01-01

    This article discusses the views of the teologian and legal scholar Ibn Ḥazm of Cordoba (d. 456/1064) on homosexuality. Although reference is made to his literary work Ṭawq al-ḥamāma, which is rich in anecdotes on homoerotic attraction, the article focuses on Ibn Ḥazm's multivolume legal tract Kitāb al-Muḥallā, a work written from a Ẓāhirī, or literalist perspective. A step-by-step analysis of Ibn Hazm's legal reasoning on homosexuality, both male (

  3. Counseling Issues for Adult Women in Career Transition

    Science.gov (United States)

    Ronzio, Cynthia R.

    2012-01-01

    This article addresses current psychosocial issues facing women in career transition and the implications of those issues for career counselors. Specifically, psychosocial developmental trajectories, the roles of family and relationships, the importance of underlying physical and mental health issues, and sociocultural and contextual stressors are…

  4. Transitional issues

    International Nuclear Information System (INIS)

    1998-01-01

    This discussion paper, the fifth in the series developed at the IPPSO Market Design Conference, addressed the issue of the need to prevent Ontario Hydro from taking unfair advantage of independent producers and other stakeholders through activities and investments in new power generating capacity in the transitional period leading up to deregulation. The need for controls is predicated on the assumption that the short-term actions and investments of Ontario Hydro could seriously compromise the position of independent generators, and that without such controls the level playing field essential to the operation of a competitive market, does not exist. Various actual and potential actions of Ontario Hydro were discussed, all of which point to the need for strict controls over Ontario Hydro exercising its dominant market power in an unfair way. It was recommended that as a minimum, the provincial government should no longer provide guarantees for Ontario Hydro capital projects, and that Ontario Hydro be instructed to defer any investment on new or returning generating capacity until the new market is in place. Limits could also be placed on Ontario Hydro's marketing efforts to enter into contracts during the transition period, and Ontario Hydro and municipal utilities should be required to keep separate accounts of their commercial preparation, and to settle such accounts separate from ratepayer revenue

  5. Efficacy of AZM therapy in patients with gingival overgrowth induced by Cyclosporine A: a systematic review

    Directory of Open Access Journals (Sweden)

    Deli Giorgio

    2008-12-01

    Full Text Available Abstract Background In daily clinical practice of a dental department it's common to find gingival overgrowth (GO in periodontal patients under treatment with Cyclosporine A (CsA. The pathogenesis of GO and the mechanism of action of Azithromycin (AZM are unclear. A systematic review was conducted in order to evaluate the efficacy of Azithromycin in patients with gingival overgrowth induced by assumption of Cyclosporine A. Methods A bibliographic search was performed using the online databases MEDLINE, EMBASE and Cochrane Central of Register Controlled Trials (CENTRAL in the time period between 1966 and September 2008. Results The literature search retrieved 24 articles; only 5 were Randomised Controlled Trials (RCTs, published in English, fulfilled the inclusion criteria. A great heterogeneity between proposed treatments and outcomes was found, and this did not allow to conduct a quantitative meta-analysis. The systematic review revealed that a 5-day course of Azithromycin with Scaling and Root Planing reduces the degree of gingival overgrowth, while a 7-day course of metronidazole is only effective on concomitant bacterial over-infection. Conclusion Few RCTs on the efficacy of systemic antibiotic therapy in case of GO were found in the literature review. A systemic antibiotic therapy without plaque and calculus removal is not able to reduce gingival overgrowth. The great heterogeneity of diagnostic data and outcomes is due to the lack of precise diagnostic methods and protocols about GO. Future studies need to improve both diagnostic methods and tools and adequate classification aimed to determine a correct prognosis and an appropriate therapy for gingival overgrowth.

  6. Review on Malaysian Rail Transit Operation and Management System: Issues and Solution in Integration

    Science.gov (United States)

    Masirin, Mohd Idrus Mohd; Salin, Aminah Mohd; Zainorabidin, Adnan; Martin, David; Samsuddin, Norshakina

    2017-08-01

    In any context, operation and management of transportation systems are key issues which may affect both life quality and economic development. In large urban agglomerations, an efficient public transportation system may help abate the negative externalities of private car use such as congestion, air and noise pollution, accident and fuel consumption, without excessively penalizing user travel times or zone accessibility. Thus, this study is conducted to appraise the Malaysian rural rail transit operation and management system, which are considered important as there are many issues and solution in integration of the services that need to be tackled more conscientiously. The purpose of this paper is to describe some of the most important issues on integration of services and rail transit system in Malaysian and how to solve or reduce these problems and conflicts. In this paper, it consists of the historical development of rail transit construction in Malaysia. This paper also attempts to identify the important issues related to rail transit services and integration in Malaysian rural rail operation and management system. Comparison is also conducted with other countries such as UK, France, and Japan. Finally, a critical analysis is presented in this paper by looking at the possible application for future Malaysian rail transit operation system and management, especially focusing on enhancing the quality of Malaysian rural rail transit. In conclusion, this paper is expected to successfully review and appraise the existing Malaysian rural rail transit operation and management system pertaining to issues & solution in integration. It is also hoped that reformation or transformation of present service delivery quality of the rail transit operation and management will enable Malaysia to succeed in transforming Malaysian transportation system to greater heights.

  7. Transit's leading edge : innovations in service and technology : issue paper 7

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-11-01

    The Canadian Urban Transit Association is committed to raising awareness of the social, environmental and economic benefits of mass transit systems. Innovation is needed to address the challenges of attracting new riders, resolving fiscal imbalances, and meeting environmental concerns. This issue paper presents examples of how Canada's transit industry has used innovation to address the issue of climate change and fight smog. It includes a brief description of some of the ways that Canadian transit suppliers and transit systems are going green: Canada's bus builders are developing hybrid buses; Grand River Transit is improving air quality with clean diesel; Montreal's Transit Society is reducing emissions with biodiesel buses; Saskatoon Transit Service is using biodiesel buses; Laval's Transit Society is listening to customer complaints in an effort to reduce response times and improve customer service; Canadian Urban Transit Association is improving customer service; Transit Windsor is promoting a smog solution; Winnipeg Transit is working with employers to boost ridership; Trapeze Software Group is providing customers with quick and accurate trip itineraries; St. John's Transportation Commission has added solar-powered, light emitting diode illumination to bus stops; the City of Ottawa has an established transit priority measures; and, Infodev EDI Inc. has supplied automated high-technology solutions for passenger counting and vehicle location tracking to several Canadian transit systems. refs., figs.

  8. Transition costs in the electricity industry: A summary of issues

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, L.; Hirst, E.; Hadley, S.

    1996-10-01

    Progress is evident as the restructuring debate in the U.S. electricity industry completes its third year. The Federal Energy Regulatory Commission released a final rule on transmission open access-a key element to facilitate more efficient wholesale markets. The majority of states have initiated investigations or discussions on restructuring retail markets. Yet hurdles remain in formulating and implementing state-level restructuring proposals. Perhaps foremost among these hurdles is the issue of transition costs (the potential monetary losses experienced by utilities, consumers, and other economic actors as a result of government initiatives to transform electricity generation from a regulated to a competitive market). Transition costs are approximately equal to the difference between the embedded cost for generation services under traditional cost-of-service regulation and the competitive-market price for power. When government takes action to open current monopoly franchises to multiple generation providers and the competitive-market price falls below embedded generation costs, then transition costs will arise. Transition costs will include one or more of the following four classes of costs: (1) assets, primarily utility-owned power plants; (2) liabilities, primarily long-term power-purchase and fuel-supply contracts; (3) regulatory assets, including deferred expenses and costs that regulators allow utilities to place on their balance sheets; and (4) public-policy programs, such as energy efficiency, low-income programs, and research and development. What is at issue in the transition-cost debate? The debate turns on four questions: (1) How large are the potential transition costs from restructuring? (2) How are these costs estimated? (3) What, if anything, might be done to address these costs? (4) Who will ultimately pay for any remaining costs and how? This paper summarizes some of the key results from a project at ORNL that addresses these four questions.

  9. Political transition and emergent forest-conservation issues in Myanmar.

    Science.gov (United States)

    Prescott, Graham W; Sutherland, William J; Aguirre, Daniel; Baird, Matthew; Bowman, Vicky; Brunner, Jake; Connette, Grant M; Cosier, Martin; Dapice, David; De Alban, Jose Don T; Diment, Alex; Fogerite, Julia; Fox, Jefferson; Hlaing, Win; Htun, Saw; Hurd, Jack; LaJeunesse Connette, Katherine; Lasmana, Felicia; Lim, Cheng Ling; Lynam, Antony; Maung, Aye Chan; McCarron, Benjamin; McCarthy, John F; McShea, William J; Momberg, Frank; Mon, Myat Su; Myint, Than; Oberndorf, Robert; Oo, Thaung Naing; Phelps, Jacob; Rao, Madhu; Schmidt-Vogt, Dietrich; Speechly, Hugh; Springate-Baginski, Oliver; Steinmetz, Robert; Talbott, Kirk; Than, Maung Maung; Thaung, Tint Lwin; Thawng, Salai Cung Lian; Thein, Kyaw Min; Thein, Shwe; Tizard, Robert; Whitten, Tony; Williams, Guy; Wilson, Trevor; Woods, Kevin; Ziegler, Alan D; Zrust, Michal; Webb, Edward L

    2017-12-01

    Political and economic transitions have had substantial impacts on forest conservation. Where transitions are underway or anticipated, historical precedent and methods for systematically assessing future trends should be used to anticipate likely threats to forest conservation and design appropriate and prescient policy measures to counteract them. Myanmar is transitioning from an authoritarian, centralized state with a highly regulated economy to a more decentralized and economically liberal democracy and is working to end a long-running civil war. With these transitions in mind, we used a horizon-scanning approach to assess the 40 emerging issues most affecting Myanmar's forests, including internal conflict, land-tenure insecurity, large-scale agricultural development, demise of state timber enterprises, shortfalls in government revenue and capacity, and opening of new deforestation frontiers with new roads, mines, and hydroelectric dams. Averting these threats will require, for example, overhauling governance models, building capacity, improving infrastructure- and energy-project planning, and reforming land-tenure and environmental-protection laws. Although challenges to conservation in Myanmar are daunting, the political transition offers an opportunity for conservationists and researchers to help shape a future that enhances Myanmar's social, economic, and environmental potential while learning and applying lessons from other countries. Our approach and results are relevant to other countries undergoing similar transitions. © 2017 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

  10. Treatment issues for children with epilepsy transitioning to adult care.

    Science.gov (United States)

    Nabbout, Rima; Camfield, Carol S; Andrade, Danielle M; Arzimanoglou, Alexis; Chiron, Catherine; Cramer, Joyce A; French, Jacqueline A; Kossoff, Eric; Mula, Marco; Camfield, Peter R

    2017-04-01

    This is the third of three papers that summarize the second symposium on Transition in Epilepsies held in Paris in June 2016. This paper focuses on treatment issues that arise during the course of childhood epilepsy and make the process of transition to adult care more complicated. Some AEDs used during childhood, such as stiripentol, vigabatrin, and cannabidiol, are unfamiliar to adult epilepsy specialists. In addition, new drugs are being developed for treatment of specific childhood onset epilepsy syndromes and have no indication yet for adults. The ketogenic diet may be effective during childhood but is difficult to continue in adult care. Regional adult epilepsy diet clinics could be helpful. Polytherapy is common for patients transitioning to adult care. Although these complex AED regimes are difficult, they are often possible to simplify. AEDs used in childhood may need to be reconsidered in adulthood. Rescue medications to stop prolonged seizures and clusters of seizures are in wide home use in children and can be continued in adulthood. Adherence/compliance is notoriously difficult for adolescents, but there are simple clinical approaches that should be helpful. Mental health issues including depression and anxiety are not always diagnosed and treated in children and young adults even though effective treatments are available. Attention deficit hyperactivity disorder and aggressive behavior disorders may interfere with transition and successful adulthood but these can be treated. For the majority, the adult social outcome of children with epilepsy is unsatisfactory with few proven interventions. The interface between pediatric and adult care for children with epilepsy is becoming increasingly complicated with a need for more comprehensive transition programs and adult epileptologists who are knowledgeable about special treatments that benefit this group of patients. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. The High Jump: Transition Issues of Learning Disabled Students and Their Parents.

    Science.gov (United States)

    Ness, Jean E.

    1989-01-01

    Issues that face learning-disabled students and their parents during the transition from a secondary to a postsecondary setting are explored, and recommendations are offered for consideration in resolving problems during this period. (JDD)

  12. Short-term azithromycin treatment promotes cornea allograft survival in the rat.

    Science.gov (United States)

    Wacker, Katrin; Denker, Sophy; Hildebrand, Antonia; Eberwein, Philipp; Reinhard, Thomas; Schwartzkopff, Johannes

    2013-01-01

    Any inflammatory response following corneal transplantation may induce rejection and irreversible graft failure. The purpose of this study is to analyze the anti-inflammatory effect of azithromycin (AZM) following experimental keratoplasty in rats. Corneal transplants were performed between Fisher-donor and Lewis-recipient rats. Recipients were postoperatively treated three times daily with AZM, miglyol, ofloxacin or dexamethasone eye drops. As an additional control, AZM was applied following syngeneic keratoplasty. Furthermore, short-term treatments with AZM for seven days perioperatively or with AZM only three days prior to the transplantation were compared to appropriate controls. All transplants were monitored clinically for opacity, edema, and vascularization. Infiltrating CD45(+), CD4(+), CD8(+), CD25(+), CD161(+) and CD163(+) cells were quantified via immunohistochemistry. AZM significantly promoted corneal graft survival compared with miglyol or ofloxacin treatment. This effect was comparable to topical dexamethasone. No adverse AZM effect was observed. Histology confirmed a significant reduction of infiltrating leukocytes. The short-term application of AZM for three days prior to transplantation or for seven days perioperatively reduced corneal graft rejection significantly compared with the controls. Along with antibiotic properties, topical AZM has a strong anti-inflammatory effect. Following keratoplasty, this effect is comparable to topical dexamethasone without the risk of steroid-induced adverse effects. Short-term treatment with AZM three days prior to the transplantation was sufficient to promote graft survival in the rat keratoplasty model. We therefore suggest further assessing the anti-inflammatory function of topical AZM following keratoplasty in humans.

  13. Short-term azithromycin treatment promotes cornea allograft survival in the rat.

    Directory of Open Access Journals (Sweden)

    Katrin Wacker

    Full Text Available Any inflammatory response following corneal transplantation may induce rejection and irreversible graft failure. The purpose of this study is to analyze the anti-inflammatory effect of azithromycin (AZM following experimental keratoplasty in rats.Corneal transplants were performed between Fisher-donor and Lewis-recipient rats. Recipients were postoperatively treated three times daily with AZM, miglyol, ofloxacin or dexamethasone eye drops. As an additional control, AZM was applied following syngeneic keratoplasty. Furthermore, short-term treatments with AZM for seven days perioperatively or with AZM only three days prior to the transplantation were compared to appropriate controls. All transplants were monitored clinically for opacity, edema, and vascularization. Infiltrating CD45(+, CD4(+, CD8(+, CD25(+, CD161(+ and CD163(+ cells were quantified via immunohistochemistry.AZM significantly promoted corneal graft survival compared with miglyol or ofloxacin treatment. This effect was comparable to topical dexamethasone. No adverse AZM effect was observed. Histology confirmed a significant reduction of infiltrating leukocytes. The short-term application of AZM for three days prior to transplantation or for seven days perioperatively reduced corneal graft rejection significantly compared with the controls.Along with antibiotic properties, topical AZM has a strong anti-inflammatory effect. Following keratoplasty, this effect is comparable to topical dexamethasone without the risk of steroid-induced adverse effects. Short-term treatment with AZM three days prior to the transplantation was sufficient to promote graft survival in the rat keratoplasty model. We therefore suggest further assessing the anti-inflammatory function of topical AZM following keratoplasty in humans.

  14. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4.

    Science.gov (United States)

    Tsubouchi, Kazuya; Araya, Jun; Minagawa, Shunsuke; Hara, Hiromichi; Ichikawa, Akihiro; Saito, Nayuta; Kadota, Tsukasa; Sato, Nahoko; Yoshida, Masahiro; Kurita, Yusuke; Kobayashi, Kenji; Ito, Saburo; Fujita, Yu; Utsumi, Hirofumi; Yanagisawa, Haruhiko; Hashimoto, Mitsuo; Wakui, Hiroshi; Yoshii, Yutaka; Ishikawa, Takeo; Numata, Takanori; Kaneko, Yumi; Asano, Hisatoshi; Yamashita, Makoto; Odaka, Makoto; Morikawa, Toshiaki; Nakayama, Katsutoshi; Nakanishi, Yoichi; Kuwano, Kazuyoshi

    2017-08-03

    Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB (transforming growth factor β) is one of the major profibrotic cytokines for myofibroblast differentiation and NOX4 (NADPH oxidase 4) has an essential role in TGFB-mediated cell signaling. Azithromycin (AZM), a second-generation antibacterial macrolide, has a pleiotropic effect on cellular processes including proteostasis. Hence, we hypothesized that AZM may regulate NOX4 levels by modulating proteostasis machineries, resulting in inhibition of TGFB-associated lung fibrosis development. Human lung fibroblasts (LF) were used to evaluate TGFB-induced myofibroblast differentiation. With respect to NOX4 regulation via proteostasis, assays for macroautophagy/autophagy, the unfolded protein response (UPR), and proteasome activity were performed. The potential anti-fibrotic property of AZM was examined by using bleomycin (BLM)-induced lung fibrosis mouse models. TGFB-induced NOX4 and myofibroblast differentiation were clearly inhibited by AZM treatment in LF. AZM-mediated NOX4 reduction was restored by treatment with MG132, a proteasome inhibitor. AZM inhibited autophagy and enhanced the UPR. Autophagy inhibition by AZM was linked to ubiquitination of NOX4 via increased protein levels of STUB1 (STIP1 homology and U-box containing protein 1), an E3 ubiquitin ligase. An increased UPR by AZM was associated with enhanced proteasome activity. AZM suppressed lung fibrosis development induced by BLM with concomitantly reduced NOX4 protein levels and enhanced proteasome activation. These results suggest that AZM suppresses NOX4 by promoting proteasomal degradation, resulting in inhibition of TGFB-induced myofibroblast differentiation and lung fibrosis development. AZM may be a candidate for the treatment of the fibrotic lung disease IPF.

  15. Safety issues in urban transit facilities for hydrogen-fueled buses

    International Nuclear Information System (INIS)

    Hay, R.H.; Ducharme, P.

    2004-01-01

    'Full text:' The Canadian Transportation Fuel Cell Alliance (CTFCA), created by the Canadian Government as part of its 2000 Climate Change Action Plan, has commissioned MARCON-DDM's Hydrogen Intervention Team (HIT) to provide a roadmap for urban transit systems that wish to move to hydrogen fuel cell-powered bus fleets. HIT is currently in the process of gathering information from hydrogen technology providers, bus manufacturers, fuelling system providers and urban transit systems in Canada, the US and Europe. In September, HIT will be in a position to provide a hands-on perspective of the introduction of fuel-cell buses in the Canadian environment. Part of the process of adding hydrogen-fueled busses to urban transit systems involves phasing in the new technology to minimize the economic cost. This involves substituting hydrogen buses into the normal bus procurement life cycle and maximizing the use of existing facilities for garaging, maintenance and fueling. Using a schematic outline of an urban transit system, this presentation will outline the safety issues specific to hydrogen in such systems, particularly for garaging, maintenance and fueling components. It will then outline how safety of these component is addressed in current and proposed codes, standards and recommended practices. Based on these requirements the impact of the introduction of hydrogen-fueled buses on each component of the transit system will be addressed in terms of the adaptations of current facilities and practices or the requirements for new facilities and practices. (author)

  16. Exercise azm-e-nau-3, the laboratory perspective

    International Nuclear Information System (INIS)

    Sharif, T.B.

    2013-01-01

    Objective: To describe the adequacy of laboratory equipment and human resource for dealing one thousand war wounded casualties. Study Design: A descriptive study. Place and Duration of Study: Combined Military Hospital Bahawalpur, from 10th April to 19th April 2010. Material and Methods: Two teams each headed by a qualified pathologist worked round the clock in twelve hour shift dealing with the samples of war wounded (WW) casualties along with routine indoor /outdoor workload. Receipt of samples, analysis, reporting, record keeping, blood donation and transfusion were according to the protocol following turn around time (TAT). Results: A total of 5487 analyses were done in a period of ten days. All range of investigations were requested but blood complete picture (CP) constituted the maximum (33.9%) followed by hepatitis screening (22.7%) and biochemical profiles (17%). Other investigations were in connection with the preparation of the patients for surgery. A total of 101 pints of blood were issued during the course of exercise, with maximum on the 16th April 2010 constituting 20.7% of total. Maximum number of pints of blood issued to any single WW casualty was five amounting to 4.9% of the total. Conclusion: CMH Bahawalpur pathology laboratory successfully managed the load of 1000 WW casualties by providing prompt laboratory support for treatment, by timely delivery of requisite results of investigations and blood transfusion. (author)

  17. Strategic and policy issues raised by the transition from thermal to fast nuclear systems

    International Nuclear Information System (INIS)

    2009-01-01

    The renewed interest in nuclear energy triggered by concerns about global climate change and security of supply, which could lead to substantial growth in nuclear electricity generation, enhances the attractiveness of fast neutron reactors with closed fuel cycles. Moving from the current fleet of thermal neutron reactors to fast neutron systems will require many decades and extensive RD-D efforts. This book identifies and analyses key strategic and policy issues raised by such a transition, aiming at providing guidance to decision makers on the best approaches for implementing transition scenarios. The topics covered in this book will be of interest to government and nuclear industry policy makers as well as to specialists working on nuclear energy system analyses and advanced fuel cycle issues. (author)

  18. Social Inequality, Life Course Transitions, and Adolescent Development: Introduction to the Special Issue.

    Science.gov (United States)

    Buchmann, Marlis; Steinhoff, Annekatrin

    2017-10-01

    Conceptualizing adolescent development within a life course framework that links the perspectives on social inequality and early life course transitions has largely been absent from previous research. Such a conceptual model is needed, however, in order to understand how the individual development of agentic capacities and the opportunities and constraints inherent in the social contexts of growing up interact and jointly affect young people's trajectories across the adolescent life stage. We present the corner stones of the conceptual "trident" of social inequality, life course transitions, and adolescent development and identify three major themes the eleven contributions to this special issue address within this conceptual framework: social and individual prerequisites and consequences of coping with life course transitions; intergenerational transmission belts of social inequality; socialization of agency in and outside the family home. These three themes exemplify the great analytical potential inherent in this framework.

  19. Evaluation of the Microbiological Efficacy of a Single 2-Gram Dose of Extended-Release Azithromycin by Population Pharmacokinetics and Simulation in Japanese Patients with Gonococcal Urethritis.

    Science.gov (United States)

    Soda, Midori; Ito, Shin; Matsumaru, Naoki; Nakamura, Sakiko; Nagase, Izumi; Takahashi, Hikari; Ohno, Yuta; Yasuda, Mitsuru; Yamamoto, Miho; Tsukamoto, Katsura; Itoh, Yoshinori; Deguchi, Takashi; Kitaichi, Kiyoyuki

    2018-01-01

    The objective of this study was to analyze the relationship between the pharmacokinetic (PK)/pharmacodynamic (PD) parameters of a single 2-g dose of extended-release formulation of azithromycin (AZM-SR) and its microbiological efficacy against gonococcal urethritis. Fifty male patients with gonococcal urethritis were enrolled in this study. In 36 patients, the plasma AZM concentrations were measured using liquid chromatography-tandem mass spectrometry, the AZM MIC values for the Neisseria gonorrhoeae isolates were determined, and the microbiological outcomes were assessed. AZM-SR monotherapy eradicated N. gonorrhoeae in 30 (83%) of the 36 patients. AZM MICs ranged from 0.03 to 2 mg/liter. The mean value of the area under the concentration-time curve (AUC), estimated by population PK analysis using a two-compartment model, was 20.8 mg · h/liter. Logistic regression analysis showed that the PK/PD target value required to predict an N. gonorrhoeae eradication rate of ≥95% was a calculated AUC/MIC of ≥59.5. The AUC/MIC value was significantly higher in patients who achieved microbiological cure than in patients who achieved microbiological failure. Monte Carlo simulation using this MIC distribution revealed that the probability that AZM-SR monotherapy would produce an AUC/MIC exceeding the AUC/MIC target of 59.5 was 47%. Furthermore, the MIC distribution for strains isolated in this study was mostly consistent with that for strains currently circulating in Japan. In conclusion, in Japan, AZM-SR monotherapy may not be effective against gonococcal urethritis. Therefore, use of a single 2-g dose of AZM-SR either with or without other antibiotics could be an option to treat gonococcal urethritis if patients are allergic to ceftriaxone and spectinomycin or are diagnosed to be infected with an AZM-sensitive strain. Copyright © 2017 American Society for Microbiology.

  20. Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

    International Nuclear Information System (INIS)

    Banaee, J.

    2002-01-01

    A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances

  1. Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

    Energy Technology Data Exchange (ETDEWEB)

    Banaee, J.

    2002-05-16

    A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances.

  2. Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

    Energy Technology Data Exchange (ETDEWEB)

    Banaee, Jila

    2002-08-01

    A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances.

  3. Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary growth phase killing of P. aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr -/--mice

    DEFF Research Database (Denmark)

    Hoffmann, N.; Lee, Bao le ri; Hentzer, Morten

    2007-01-01

    The consequences of O-acetylated alginate-producing Pseudomonas aeruginosa biofilms in the lungs of chronically infected cystic fibrosis (CF) patients are tolerance to both antibiotic treatments and effects on the innate and the adaptive defense mechanisms. In clinical trials, azithromycin (AZM...... and the complement system. Moreover, we show that AZM may affect the polymerization of P. aeruginosa alginate by the incomplete precipitation of polymerized alginate and high levels of readily dialyzable uronic acids. In addition, we find that mucoid bacteria in the stationary growth phase became sensitive to AZM......, whereas cells in the exponential phase did not. Interestingly, AZM-treated P. aeruginosa lasI mutants appeared to be particularly resistant to serum, whereas bacteria with a functional QS system did not. We show in a CF mouse model of chronic P. aeruginosa lung infection that AZM treatment results...

  4. Issues for resolving adverse effects on the safety culture of human work underload and workload transitions in complex human-machine systems

    International Nuclear Information System (INIS)

    Ryan, T.G.

    1996-01-01

    A workshop was conducted whose specific purpose was to build on earlier work of the US National Research Council, US federal government agencies, and the larger human factors community to: (1) clarify human factors issues pertaining to degraded safety performance in advanced human-machine systems(e.g., nuclear production, transportation, aerospace) due to human work underload and workload transition, and (2) develop strategies for resolving these issues. The workshop affirmed that: (1) work underload and workload transition are issues that will have to be addressed by designers of advanced human-machine systems, especially those relying on automation, if cost, performance, safety, and operator acceptability are to be optimized, (2) human machine allocation models, standards and guidelines which go beyond simple capability approaches will be needed to preclude or seriously diminish the work underload and workload transition problems, and (3) the 16 workload definition, measurement, situational awareness, and trust issues identified during the workshop, need resolution if these models, standards, and guidelines are to be achieved

  5. An Analysis of Technological Issues Emanating from Faculty Transition to a New Learning Management System

    Science.gov (United States)

    Sanga, Mapopa William

    2016-01-01

    This case study investigated the process 119 faculty members underwent as they transitioned from using Desire to Learn (D2L) learning management system (LMS), to using Canvas LMS. Other than analyzing technological issues faculty members encountered while navigating various aspects of the Canvas interface, the study also analyzed technological…

  6. Azithromycin Synergistically Enhances Anti-Proliferative Activity of Vincristine in Cervical and Gastric Cancer Cells

    International Nuclear Information System (INIS)

    Zhou, Xuezhang; Zhang, Yuyan; Li, Yong; Hao, Xiujing; Liu, Xiaoming; Wang, Yujiong

    2012-01-01

    In this study, the anti-proliferative and anticancer activity of azithromycin (AZM) was examined. In the presence of AZM, cell growth was inhibited more effectively in Hela and SGC-7901 cancer cells, relative to transformed BHK-21 cells. The respective 50% inhibition of cell growth (IC 50 ) values for Hela, SGC-7901 and BHK-21 were 15.66, 26.05 and 91.00 µg/mL at 72 h post incubation, indicative of a selective cytotoxicity against cancer cells. Cell apoptosis analysis using Hoechst nuclear staining and annexin V-FITC binding assay further demonstrated that AZM was capable of inducing apoptosis in both cancer cells and transformed cells. The apoptosis induced by AZM was partly through a caspase-dependent mechanism with an up-regulation of apoptotic protein cleavage PARP and caspase-3 products, as well as a down-regulation of anti-apoptotic proteins, Mcl-1, bcl-2 and bcl-X1. More importantly, a combination of AZM and a low dose of the common anti-cancer chemotherapeutic agent vincristine (VCR), produced a selectively synergistic effect on apoptosis of Hela and SGC-7901 cells, but not BHK-21 cells. In the presence of 12.50 μg/mL of VCR, the respective IC 50 values of Hela, SGC-7901 and BHK-21 cells to AZM were reduced to 9.47 µg/mL, 8.43 µg/mL and 40.15 µg/mL at 72 h after the incubation, suggesting that the cytotoxicity of AZM had a selective anti-cancer effect on cancer over transformed cells in vitro. These results imply that AZM may be a potential anticancer agent for use in chemotherapy regimens, and it may minimize side effects via reduction of dosage and enhancing the effectiveness common chemotherapeutic drugs

  7. Management issues of congenital adrenal hyperplasia during the transition from pediatric to adult care.

    Science.gov (United States)

    Choi, Jin-Ho; Yoo, Han-Wook

    2017-02-01

    Steroid 21-hydroxylase deficiency is the most prevalent form of congenital adrenal hyperplasia (CAH), accounting for approximately 95% of cases. With the advent of newborn screening and hormone replacement therapy, most children with CAH survive into adulthood. Adolescents and adults with CAH experience a number of complications, including short stature, obesity, infertility, tumor, osteoporosis, and reduced quality of life. Transition from pediatric to adult care and management of long-term complications are challenging for both patients and health-care providers. Psychosocial issues frequently affect adherence to glucocorticoid treatment. Therefore, the safe transition of adolescents to adult care requires regular follow-up of patients by a multidisciplinary team including pediatric and adult endocrinologists. The major goals for management of adults with 21-hydroxylase deficiency are to minimize the long-term complications of glucocorticoid therapy, reduce hyperandrogenism, prevent adrenal or testicular adrenal rest tumors, maintain fertility, and improve quality of life. Optimized medical or surgical treatment strategies should be developed through coordinated care, both during transition periods and throughout patients' lifetimes. This review will summarize current knowledge on the management of adults with CAH, and suggested appropriate approaches to the transition from pediatric to adult care.

  8. AzaSite® inhibits Staphylococcus aureus and coagulase-negative Staphylococcus biofilm formation in vitro.

    Science.gov (United States)

    Wu, Eric C; Kowalski, Regis P; Romanowski, Eric G; Mah, Francis S; Gordon, Y Jerold; Shanks, Robert M Q

    2010-12-01

    The aim of this study was to analyze the effect of azithromycin (AZM) 1% ophthalmic solution in DuraSite® (AzaSite®) on biofilm formation by Staphylococcus aureus and coagulase-negative staphylococci in vitro. Susceptible and resistant clinical strains (n = 8) of S. aureus and coagulase-negative staphylococci were challenged with serial dilutions of AzaSite® and its components: AZM, benzalkonium chloride (BAK), and the DuraSite drug delivery vehicle. After 20 h of incubation, bacterial growth was quantified using a spectrophotometer (A = 600 nm). Plates were stained with crystal violet and biofilm formation was quantified spectrophotometrically at A = 590 nm. AzaSite® and AZM inhibited bacterial growth (P reduction in biofilm formation (P reduction in biofilm formation at concentrations from 1.25 to 10 mg/mL in most strains. DuraSite® inhibited biofilm formation at concentrations between 10% and 2.5% in all studied strains (P < 0.05), without affecting bacterial growth. BAK inhibited bacterial growth and biofilm formation in all strains between concentrations of 0.042 and 0.375 mg/mL (P < 0.05). AzaSite®, AZM, or BAK prevented biofilm formation by inhibiting growth of AZM-susceptible strains. AzaSite®, AZM, and DuraSite® also reduced biofilm formation at subinhibitory concentrations for growth. Our data indicate that AZM has a moderate inhibitory effect on biofilm formation, whereas DuraSite® appears to play a greater role in the inhibition of staphylococcal biofilm formation by AzaSite®.

  9. Antivirulence activity of azithromycin in Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Francesco eImperi

    2014-04-01

    Full Text Available Antibiotics represent our bulwark to combat bacterial infections, but the spread of antibiotic resistance compromises their clinical efficacy. Alternatives to conventional antibiotics are urgently needed in order to complement the existing antibacterial arsenal. The macrolide antibiotic azithromycin (AZM provides a paradigmatic example of an unconventional antibacterial drug. Besides its growth-inhibiting activity, AZM displays potent anti-inflammatory properties, as well as antivirulence activity on some intrinsically resistant bacteria, such as Pseudomonas aeruginosa. In this bacterium, the antivirulence activity of AZM mainly relies on its ability to interact with the ribosome, resulting in direct and/or indirect repression of specific subsets of genes involved in virulence, quorum sensing, biofilm formation and intrinsic antibiotic resistance. Both clinical experience and clinical trials have shown the efficacy of AZM in the treatment of chronic pulmonary infections caused by P. aeruginosa. The aim of this review is to combine results from laboratory studies with evidence from clinical trials in order to unify the information on the in vivo mode of action of AZM in P. aeruginosa infection.

  10. Single window for issuing licenses for export and import of ionizing radiation sources and transit of radioactive sources

    International Nuclear Information System (INIS)

    Sandev, T.; Stamenov, R.; Misevska, A.; Georgievska-Dimitrevski, B.; Angelovski, G.

    2009-01-01

    In this paper we present the electronic system for application and issuing licenses for export, import and transit of goods (EXIM), particularly for ionizing radiation sources, in the Republic of Macedonia. This system is a modern and helpful tool for simple issuing licenses, for establishing a unique database and it represents a harmonized system for exchanging information between the governmental, public and private legal persons in the Republic of Macedonia. (author)

  11. Comparative Plasma Exposure and Lung Distribution of Two Human Use Commercial Azithromycin Formulations Assessed in Murine Model: A Preclinical Study

    OpenAIRE

    Rivulgo, Virginia Margarita; Sparo, Mónica; Ceci, Mónica; Fumuso, Elida; Confalonieri, Alejandra; Delpech, Gastón; Sanchez Bruni, Sergio Fabian

    2016-01-01

    Azithromycin(AZM)therapeutic failure and relapses of patients treated with generic -35 formulations have been observed in clinical practice.The main goal of this research was 36 to compare in a pre-clinical study the serum exposure and lung tissue concentrationof 37 two commercial formulations AZM-based in murine model. The current study involved 38 264 healthy Balb-C.Mice were divided in two groups (n=44): Animals of Group A 39 (Reference Formulation ?R-) were orally treated with AZM suspens...

  12. Safety culture and organizational issues during transition from operation to decommissioning of NPPs

    International Nuclear Information System (INIS)

    Slavcheva, K.; Mori, M.; D'Amico, N.; Sollima, C.

    2005-01-01

    The paper highlights the critical safety issues in a Nuclear Power Plant (NPP) to be managed during the transition period from operation to decommissioning. Pre-shutdown is an important period of a NPP lifetime due to the changes and issues to be faced by the NPP management, which include safety culture issues, organizational issues, plant safety issues and nuclear waste issues. Preservation of staff competence and moral, management and organizational capability, preservation of knowledge and corporate memory, preservation of safety culture, surveillance and permanent control to maintain adequate level of nuclear and radiation safety, development of appropriate solutions for the new incoming issues are the key challenges to be timely faced. The uncertainty regarding the future of the site, the future of the workers and the incoming re-organization originate numerous additional issues including stress for the personnel. It is necessary to take appropriate actions to reduce the uncertainty. The regulatory regime continues with the same rules as during operation. Responsibility for safety remains with the licensee and the regulatory supervision continues and oversees the safe operation and security of the NPP, the safe management and storage of spent nuclear fuel and radioactive waste. Anticipated attention from the Operator and the Regulator to key organizational and safety culture issues during the pre-shutdown phase has shown to be an effective preventive action. The Operator has to aim to preserve staff competence and motivation, preserve corporate memory, safety culture, reinforce monitoring and control on the health risk of workers and population, preserve the technical part of the organization from external disturb and distractions, ensure transparency and develop strategies to solve forthcoming issues. The Regulator has to aim to reorient its supervision, train its personnel and adapt its tools to the new situation, keep adequate presence onsite, keep dialogue

  13. Introduction to Focus Issue: Rhythms and Dynamic Transitions in Neurological Disease: Modeling, Computation, and Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Kaper, Tasso J., E-mail: tasso@bu.edu; Kramer, Mark A., E-mail: mak@bu.edu [Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02215 (United States); Rotstein, Horacio G., E-mail: horacio@njit.edu [Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, New Jersey 07102 (United States)

    2013-12-15

    Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases.

  14. Introduction to Focus Issue: Rhythms and Dynamic Transitions in Neurological Disease: Modeling, Computation, and Experiment

    International Nuclear Information System (INIS)

    Kaper, Tasso J.; Kramer, Mark A.; Rotstein, Horacio G.

    2013-01-01

    Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases

  15. Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015.

    Science.gov (United States)

    Yasuda, Mitsuru; Ito, Shin; Hatazaki, Kyoko; Deguchi, Takashi

    2016-12-01

    The antimicrobial resistance of Neisseria gonorrhoeae is a serious problem worldwide. In this study, we examined the susceptibility of N. gonorrhoeae isolated from male gonococcal urethritis in Sendai in 2014 and 2015. Furthermore, of all cases, we investigated the clinical efficacy of a single 2-g dose of extended-release azithromycin (AZM-SR) in the treatment of male gonococcal urethritis retrospectively. Sixty N. gonorrhoeae strains in 2014 and 54 strains in 2015 were isolated from male gonococcal urethritis and stored each year. The MIC of AZM was ≥1 mg/L in 4 strains (6.7%) in 2014 and in 13 strains (24.1%) in 2015 and the number of strains having ≥1 mg/L MIC increased significantly (P = 0.016). Microbiological efficacy was evaluated in 32 and 29 of these patients, and the rates of treatment success were 93.8% and 79.3%, respectively. All of the treatment failures were caused by strains having a MIC of AZM of ≥0.5 mg/L. In particular, the increase in the isolates having a MIC of AZM of ≥1 mg/L was remarkable. Therefore, it was thought that the increase in these strains was the reason for the increase in treatment failures in 2015. Because no other drug is effective, it is currently necessary to use AZM-SR to treat gonococcal infections caused by ceftriaxone-resistant strains or patients allergic to ceftriaxone. To prevent a further increase in resistance to AZM, we should not use AZM-SR to treat normal cases of gonococcal infection. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  16. AcEST: DK957075 [AcEST

    Lifescience Database Archive (English)

    Full Text Available patitis C virus gen... 33 0.77 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...jct: 2362 ---------SGDPGHSTGGGTTGETSKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake

  17. Healthcare transition in persons with intellectual disabilities: general issues, the Maastricht model, and Prader-Willi syndrome.

    Science.gov (United States)

    Schrander-Stumpel, Constance T R M; Sinnema, Margje; van den Hout, Lieke; Maaskant, Marian A; van Schrojenstein Lantman-de Valk, Henny M J; Wagemans, Annemieke; Schrander, Jaap J P; Curfs, Leopold M G

    2007-08-15

    In current healthcare, transitional healthcare is a very important and timely issue. Thanks to the major advances made in medical care and technology, many children with childhood onset diseases and/or genetic syndromes survive to adulthood. These children are at risk of not being provided with adequate healthcare as they reach adulthood. Healthcare transition is an essential part of healthcare provision, referred to as the shift from one type of healthcare to another. In Maastricht, we developed a transition/out clinic led by a medical doctor specialized in persons with intellectual disability (ID), together with a clinical geneticist. We aim to coordinate healthcare issues based on guidelines if available. Also questions concerning living, daily activities, relations, sexuality, and sterilization can be discussed. The aging process of persons with ID has been a topic of interest in recent years. Little is known about the aging process of people with specific syndromes, except for persons with Down syndrome. We present some data of a recent questionnaire study in persons with Prader-Willi syndrome. In only 50% in persons with a clinical diagnosis genetic test results could be reported. The majority of persons were obese. Diabetes mellitus, hypertension, skin problems, sleep apnea, and hormonal problems like osteoporosis and hypothyroidism were common. Psychiatric problems were frequent, especially in the persons with uniparental disomy. Osteoporosis and sleep apnoea seem to be underestimated. Further longitudinal research is necessary for a better understanding of the aging process in PWS. (c) 2007 Wiley-Liss, Inc.

  18. Psychosocial issues of women with type 1 diabetes transitioning to motherhood: a structured literature review.

    Science.gov (United States)

    Rasmussen, Bodil; Hendrieckx, Christel; Clarke, Brydie; Botti, Mari; Dunning, Trisha; Jenkins, Alicia; Speight, Jane

    2013-11-23

    Life transitions often involve complex decisions, challenges and changes that affect diabetes management. Transition to motherhood is a major life event accompanied by increased risk that the pregnancy will lead to or accelerate existing diabetes-related complications, as well as risk of adverse pregnancy outcomes, all of which inevitably increase anxiety. The frequency of hyperglycaemia and hypoglycaemia often increases during pregnancy, which causes concern for the health and physical well-being of the mother and unborn child. This review aimed to examine the experiences of women with T1DM focusing on the pregnancy and postnatal phases of their transition to motherhood. The structured literature review comprised a comprehensive search strategy identifying primary studies published in English between 1990-2012. Standard literature databases were searched along with the contents of diabetes-specific journals. Reference lists of included studies were checked. Search terms included: 'diabetes', 'type 1', 'pregnancy', 'motherhood', 'transition', 'social support', 'quality of life' and 'psychological well-being'. Of 112 abstracts returned, 62 articles were reviewed in full-text, and 16 met the inclusion criteria. There was a high level of diversity among these studies but three common key themes were identified. They related to physical (maternal and fetal) well-being, psychological well-being and social environment. The results were synthesized narratively. Women with type 1 diabetes experience a variety of psychosocial issues in their transition to motherhood: increased levels of anxiety, diabetes-related distress, guilt, a sense of disconnectedness from health professionals, and a focus on medicalisation of pregnancy rather than the positive transition to motherhood. A trusting relationship with health professionals, sharing experiences with other women with diabetes, active social support, shared decision and responsibilities for diabetes management assisted the

  19. Transition-cost issues for a restructuring US electricity industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Utilities regulators can use a variety of approaches to calculate transition costs. We categorized these approaches along three dimensions. The first dimension is the use of administrative vs. market procedures to value the assets in question. Administrative approaches use analytical techniques to estimate transition costs. Market valuation relies on the purchase price of particular assets to determine their market values. The second dimension concerns when the valuation is done, either before or after the restructuring of the electricity industry. The third dimension concerns the level of detail involved in the valuation, what is often called top-down vs. bottom-up valuation. This paper discusses estimation approaches, criteria to assess estimation methods, specific approaches to estimating transition costs, factors that affect transition-cost estimates, strategies to address transition costs, who should pay transition costs, and the integration of cost recovery with competitive markets.

  20. AcEST: DK957576 [AcEST

    Lifescience Database Archive (English)

    Full Text Available lyprotein OS=Hepatitis C virus gen... 33 0.90 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehe... 2362 ---------SGDPGHSTGGGTTGETSKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake

  1. AcEST: DK958683 [AcEST

    Lifescience Database Archive (English)

    Full Text Available nome polyprotein OS=Hepatitis C virus gen... 33 0.92 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...KSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake

  2. Lost in Transition: Examining Transitions in Psychotherapy Training.

    Science.gov (United States)

    Tan, Adrienne; Philipp, Diane; Malat, Jan; Feder, Victor; Kulkarni, Chetana; Lawson, Andrea; So, Vivien; Ravitz, Paula

    2015-10-01

    Disruptions are inevitable during psychiatry residency training and can affect resident learning and patient care. This exploratory study examined the nature and impact of transitions in psychotherapy training. PGY2-5 residents (45/150; 30% response rate) and psychotherapy supervisors (46/247; 18.6% response rate) were surveyed about transitional events during residency training in psychotherapy. Supervisors and residents ranked the frequency of occurrence of transitional events and their impact very similarly, as well as the "feed forward" items when transitioning to a new supervisor. Residents feeling confused or overwhelmed with the balancing of learning differing models with differing levels of comfort or knowledge was ranked as the issue that occurred most frequently by both supervisors and residents. This study highlights issues that arise at transitions during psychotherapy training in psychiatry residency. Strategies for managing these periods are discussed, with a focus on resident learning and improved continuity of patient care.

  3. AcEST: DK952719 [AcEST

    Lifescience Database Archive (English)

    Full Text Available sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 4.3 sp|Q7XWS7|FH12_ORYSJ Formin-like...---------SGDPGHSTGGGTTGETSKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake

  4. Emerging nuclear security issues for transit countries

    International Nuclear Information System (INIS)

    Gabulov, I.A.

    2003-01-01

    Full text: Tragic events of September eleventh have made nuclear terrorism dangers more evident. In the light of increased terrorism preventing the spread of nuclear and nuclear related items as well as radioactive materials that can be used for production so-called 'dirty bomb'is an urgent global claim. Nuclear Security issues cover multiple aspects of the security and first of all the threat from nuclear terrorism, detection and protection of illicit trafficking of nuclear materials and other radioactive sources, legal shipment of such type materials as well as nuclear related dual use items. In the face of emerging threats the prevention of proliferation by the development of effective national system of nuclear export controls is hugely important for transit countries like Azerbaijan with underdeveloped export controls and strategic locations along trade and smuggling routes between nuclear suppliers States and countries attempting to develop nuclear weapons or any nuclear explosive devices. Thus, in the face of increasing international threat from nuclear terrorism the role and place of Azerbaijan Republic in the struggle against terrorism increases. In this context it is very important to establish effective national capabilities for detection and prevention of illicit trafficking of radioactive and nuclear materials as well as nuclear related dual use items across Azerbaijan's borders. One of the ways for enhancing and strengthening existing activities in this field is carrying out joint actions between scientists and enforcement officials in order to improve knowledge of the front-line customs and border guard inspectors concerning multiple aspects of Nuclear Security

  5. Management of adults with paediatric-onset chronic liver disease: strategic issues for transition care.

    Science.gov (United States)

    Vajro, Pietro; Ferrante, Lorenza; Lenta, Selvaggia; Mandato, Claudia; Persico, Marcello

    2014-04-01

    Advances in the management of children with chronic liver disease have enabled many to survive into adulthood with or without their native livers, so that the most common of these conditions are becoming increasingly common in adult hepatology practice. Because the aetiologies of chronic liver disease in children may vary significantly from those in adulthood, adults with paediatric-onset chronic liver disease may often present with clinical manifestations unfamiliar to their adulthood physician. Transition of medical care to adult practice requires that the adulthood medical staff (primary physicians and subspecialists) have a comprehensive knowledge of childhood liver disease and their implications, and of the differences in caring for these patients. Pending still unavailable Scientific Society guidelines, this article examines causes, presentation modes, evaluation, management, and complications of the main paediatric-onset chronic liver diseases, and discusses key issues to aid in planning a program of transition from paediatric to adult patients. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

  6. AcEST: DK962769 [AcEST

    Lifescience Database Archive (English)

    Full Text Available e ... 31 4.5 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 4.5 sp|Q7XWS7|FH12_ORYSJ...PPPSPEAPSCLAPARAEGELEELEMVGSLEPEEEL 972 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead vi

  7. Reflections on gender issues in work transitions in Chile.

    Science.gov (United States)

    Cronin, Shawna

    2013-01-01

    To explore the work transitions of Chilean women. Observations and dialogue of Chilean women and their experiences in current and past work. A personal and historical reflection to understand the experiences of work for Chilean women. Exploring work transitions requires an understanding of the macro level historical impact on the participation of women in work in Chilean society. Macro level factors such as participation in the free labour market economy ultimately impacts on the individual choices of the women of Chile regarding their opportunities to transition into productive paid employment. The understanding of work transitions must consider the influences of the labour market economy.

  8. Examining hydrogen transitions.

    Energy Technology Data Exchange (ETDEWEB)

    Plotkin, S. E.; Energy Systems

    2007-03-01

    This report describes the results of an effort to identify key analytic issues associated with modeling a transition to hydrogen as a fuel for light duty vehicles, and using insights gained from this effort to suggest ways to improve ongoing modeling efforts. The study reported on here examined multiple hydrogen scenarios reported in the literature, identified modeling issues associated with those scenario analyses, and examined three DOE-sponsored hydrogen transition models in the context of those modeling issues. The three hydrogen transition models are HyTrans (contractor: Oak Ridge National Laboratory), MARKAL/DOE* (Brookhaven National Laboratory), and NEMS-H2 (OnLocation, Inc). The goals of these models are (1) to help DOE improve its R&D effort by identifying key technology and other roadblocks to a transition and testing its technical program goals to determine whether they are likely to lead to the market success of hydrogen technologies, (2) to evaluate alternative policies to promote a transition, and (3) to estimate the costs and benefits of alternative pathways to hydrogen development.

  9. AcEST: DK960274 [AcEST

    Lifescience Database Archive (English)

    Full Text Available _HCVBB Genome polyprotein OS=Hepatitis C virus gen... 33 0.93 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 31.2

  10. AcEST: DK949578 [AcEST

    Lifescience Database Archive (English)

    Full Text Available |POLG_HCVBB Genome polyprotein OS=Hepatitis C virus gen... 33 1.0 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...1 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 31

  11. AcEST: DK961950 [AcEST

    Lifescience Database Archive (English)

    Full Text Available VBB Genome polyprotein OS=Hepatitis C virus gen... 33 0.92 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 31.2 bit

  12. AcEST: DK948648 [AcEST

    Lifescience Database Archive (English)

    Full Text Available OLG_HCVBB Genome polyprotein OS=Hepatitis C virus gen... 33 1.0 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 31.2

  13. Safety culture and organisational issues specific to the transitional phase from operation to decommissioning of the Ignalina Nuclear Power Plant

    International Nuclear Information System (INIS)

    Medeliene, D.

    2005-01-01

    The PHARE project Support to State Nuclear Power Safety Inspectorate for safety culture and organisational issues specific to the pre-shutdown phase of Ignalina Nuclear Power Plant was aimed at providing assistance to VATESI in their task to oversee that the Ignalina Nuclear Power Plant's management and staff are able to provide an acceptable level of reactor safety taking into account possible safety culture related problems that may occur due to the decision of an early closure of both units. Safety culture is used as a concept to characterise the attitudes, behaviour and perceptions of people that are important in ensuring the safety of nuclear power facility. Since the Chernobyl accident, the International Atomic Energy Agency (IAEA) has been active in creating guidance for ensuring that an adequate safety culture can be created and maintained. The transition from operation to decommissioning introduces uncertainty for both the organisation and individuals. This creates new challenges that need to be dealt with. Although safety culture and organisational issues have to be addressed during the entire life cycle of a nuclear power plant, owing to these special challenges, it should be especially highlighted during the transitional period from operation to decommissioning. Nuclear safety experts from Sweden, Finland, Italy, the UK and Germany, as well as Lithuanian specialists, participated in the project, and it proved to be a most effective way to share experience. The aim of this brochure is to provide information about: the importance of safety culture issues during the transitional phase from operation to decommissioning of Ignalina Nuclear Power Plant; the purpose, activities and results of this PHARE project; recommendations that are provided by western experts concerning the management of safety culture issues specific to the pre-decommissioning phase of Ignalina Nuclear Power Plant. (author)

  14. Prospects and applications near ferroelectric quantum phase transitions: a key issues review

    Science.gov (United States)

    Chandra, P.; Lonzarich, G. G.; Rowley, S. E.; Scott, J. F.

    2017-11-01

    The emergence of complex and fascinating states of quantum matter in the neighborhood of zero temperature phase transitions suggests that such quantum phenomena should be studied in a variety of settings. Advanced technologies of the future may be fabricated from materials where the cooperative behavior of charge, spin and current can be manipulated at cryogenic temperatures. The progagating lattice dynamics of displacive ferroelectrics make them appealing for the study of quantum critical phenomena that is characterized by both space- and time-dependent quantities. In this key issues article we aim to provide a self-contained overview of ferroelectrics near quantum phase transitions. Unlike most magnetic cases, the ferroelectric quantum critical point can be tuned experimentally to reside at, above or below its upper critical dimension; this feature allows for detailed interplay between experiment and theory using both scaling and self-consistent field models. Empirically the sensitivity of the ferroelectric T c’s to external and to chemical pressure gives practical access to a broad range of temperature behavior over several hundreds of Kelvin. Additional degrees of freedom like charge and spin can be added and characterized systematically. Satellite memories, electrocaloric cooling and low-loss phased-array radar are among possible applications of low-temperature ferroelectrics. We end with open questions for future research that include textured polarization states and unusual forms of superconductivity that remain to be understood theoretically.

  15. Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II–acetazolamide complex

    International Nuclear Information System (INIS)

    Aggarwal, Mayank; Boone, Christopher D.; Kondeti, Bhargav; Tu, Chingkuang; Silverman, David N.; McKenna, Robert

    2013-01-01

    Here, a case study of the effects of cryoprotectants on the kinetics of carbonic anhydrase II (CA II) and its inhibition by the clinically used inhibitor acetazolamide (AZM) is presented. Protein X-ray crystallography has seen a progressive shift from data collection at cool/room temperature (277–298 K) to data collection at cryotemperature (100 K) because of its ease of crystal preparation and the lessening of the detrimental effects of radiation-induced crystal damage, with 20–25%(v/v) glycerol (GOL) being the preferred choice of cryoprotectant. Here, a case study of the effects of cryoprotectants on the kinetics of carbonic anhydrase II (CA II) and its inhibition by the clinically used inhibitor acetazolamide (AZM) is presented. Comparative studies of crystal structure, kinetics, inhibition and thermostability were performed on CA II and its complex with AZM in the presence of either GOL or sucrose. These results suggest that even though the cryoprotectant GOL was previously shown to be directly bound in the active site and to interact with AZM, it affects neither the thermostability of CA II nor the binding of AZM in the crystal structure or in solution. However, addition of GOL does affect the kinetics of CA II, presumably as it displaces the water proton-transfer network in the active site

  16. Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II–acetazolamide complex

    Energy Technology Data Exchange (ETDEWEB)

    Aggarwal, Mayank; Boone, Christopher D.; Kondeti, Bhargav; Tu, Chingkuang; Silverman, David N.; McKenna, Robert, E-mail: rmckenna@ufl.edu [University of Florida, 1600 SW Archer Road, PO Box 100245, Gainesville, FL 32610 (United States)

    2013-05-01

    Here, a case study of the effects of cryoprotectants on the kinetics of carbonic anhydrase II (CA II) and its inhibition by the clinically used inhibitor acetazolamide (AZM) is presented. Protein X-ray crystallography has seen a progressive shift from data collection at cool/room temperature (277–298 K) to data collection at cryotemperature (100 K) because of its ease of crystal preparation and the lessening of the detrimental effects of radiation-induced crystal damage, with 20–25%(v/v) glycerol (GOL) being the preferred choice of cryoprotectant. Here, a case study of the effects of cryoprotectants on the kinetics of carbonic anhydrase II (CA II) and its inhibition by the clinically used inhibitor acetazolamide (AZM) is presented. Comparative studies of crystal structure, kinetics, inhibition and thermostability were performed on CA II and its complex with AZM in the presence of either GOL or sucrose. These results suggest that even though the cryoprotectant GOL was previously shown to be directly bound in the active site and to interact with AZM, it affects neither the thermostability of CA II nor the binding of AZM in the crystal structure or in solution. However, addition of GOL does affect the kinetics of CA II, presumably as it displaces the water proton-transfer network in the active site.

  17. AcEST: DK954087 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 2 2.1 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 3.6 sp|Q7XWS7|FH12_ORYSJ Formin...uery: 326 KRLDGAAEAANAGY 367 + EA NA Y Sbjct: 322 DEIVKLVEARNAKY 335 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake

  18. One man's poison is another man's meat: Using azithromycin-induced phospholipidosis to promote ocular surface health

    International Nuclear Information System (INIS)

    Liu, Yang; Kam, Wendy R.; Ding, Juan; Sullivan, David A.

    2014-01-01

    Drug-induced phospholipidosis (PLD) is a common adverse effect which has led to the termination of clinical trials for many candidate pharmaceuticals. However, this lipid-inducing effect may be beneficial in the treatment of meibomian gland dysfunction (MGD). MGD is the major cause of dry eye disease (DED), which affects 40 million people in the USA and has no cure. Azithromycin (AZM) is a PLD-inducing antibiotic that is used off-label to treat MGD, and is presumably effective because it suppresses the MGD-associated conjunctival inflammation (i.e. posterior blepharitis) and growth of lid bacteria. We hypothesize that AZM can act directly to promote the function of human meibomian gland epithelial cells by inducing PLD in these cells, characterized by the accumulation of lipids and lysosomes. Immortalized human meibomian gland epithelial cells (HMGEC) were cultured with or without azithromycin for 5 days. Cells were evaluated for cholesterol (Filipin) and neutral lipid (LipidTox) staining, as well as the appearance of lysosomes (LysoTracker) and lamellar bodies (transmission electron microscopy, TEM). The lipid composition of cellular lysates was analyzed by high performance thin-layer chromatography. Our findings demonstrate that AZM stimulates the accumulation of free cholesterol, neutral lipids and lysosomes in HMGEC. This AZM-induced increase of neutral lipid content occurred predominantly within lysosomes. Many of these vesicles appeared to be lamellar bodies by TEM, which is the characteristic of PLD. Our findings also show that AZM promotes an accumulation of free and esterified cholesterol, as well as phospholipids in HMGECimmortalized. Our results support our hypothesis and confirm the beneficial effect of PLD induced by AZM on HMGEC. Our discovery reveals a new potential use of PLD-inducing drugs, and makes this adverse effect a beneficial effect

  19. One man's poison is another man's meat: using azithromycin-induced phospholipidosis to promote ocular surface health.

    Science.gov (United States)

    Liu, Yang; Kam, Wendy R; Ding, Juan; Sullivan, David A

    2014-06-05

    Drug-induced phospholipidosis (PLD) is a common adverse effect which has led to the termination of clinical trials for many candidate pharmaceuticals. However, this lipid-inducing effect may be beneficial in the treatment of meibomian gland dysfunction (MGD). MGD is the major cause of dry eye disease (DED), which affects 40 million people in the USA and has no cure. Azithromycin (AZM) is a PLD-inducing antibiotic that is used off-label to treat MGD, and is presumably effective because it suppresses the MGD-associated conjunctival inflammation (i.e. posterior blepharitis) and growth of lid bacteria. We hypothesize that AZM can act directly to promote the function of human meibomian gland epithelial cells by inducing PLD in these cells, characterized by the accumulation of lipids and lysosomes. Immortalized human meibomian gland epithelial cells (HMGEC) were cultured with or without azithromycin for 5 days. Cells were evaluated for cholesterol (Filipin) and neutral lipid (LipidTox) staining, as well as the appearance of lysosomes (LysoTracker) and lamellar bodies (transmission electron microscopy, TEM). The lipid composition of cellular lysates was analyzed by high performance thin-layer chromatography. Our findings demonstrate that AZM stimulates the accumulation of free cholesterol, neutral lipids and lysosomes in HMGEC. This AZM-induced increase of neutral lipid content occurred predominantly within lysosomes. Many of these vesicles appeared to be lamellar bodies by TEM, which is the characteristic of PLD. Our findings also show that AZM promotes an accumulation of free and esterified cholesterol, as well as phospholipids in HMGECimmortalized. Our results support our hypothesis and confirm the beneficial effect of PLD induced by AZM on HMGEC. Our discovery reveals a new potential use of PLD-inducing drugs, and makes this adverse effect a beneficial effect. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  20. Identification of treatment strategies for Mycoplasma genitalium-related urethritis in male patients by culturing and antimicrobial susceptibility testing.

    Science.gov (United States)

    Hamasuna, Ryoichi

    2013-02-01

    Mycoplasma genitalium was first isolated from urethral swab specimens of male patients with non-gonococcal urethritis. However, the isolation of M. genitalium strains from clinical specimens has been difficult. Co-cultivation with Vero cells is one available technique for the isolation of M. genitalium. The strains that can be used for antimicrobial susceptibility testing by broth dilution or agar dilution methods are limited. Macrolides, such as azithromycin (AZM), have the strongest activity against M. genitalium. However, AZM-resistant strains have emerged and spread. Mutations in the 23S rRNA gene contribute to the organism's macrolide resistance, which is similar to the effects of the mutations in macrolide-resistant Mycoplasma pneumoniae. Of the fluoroquinolones, moxifloxacin (MFLX) and sitafloxacin have the strongest activities against M. genitalium, while levofloxacin and ciprofloxacin are not as effective. Some clinical trials on the treatment of M. genitalium-related urethritis are available in the literature. A doxycycline regimen was microbiologically inferior to an AZM regimen. For cases of treatment failure with AZM regimens, MFLX regimens were effective.

  1. Antibacterial and synergy of berberines with antibacterial agents against clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus (MRSA).

    Science.gov (United States)

    Zuo, Guo-Ying; Li, Yang; Han, Jun; Wang, Gen-Chun; Zhang, Yun-Ling; Bian, Zhong-Qi

    2012-08-29

    Antibacterial activity of berberine (Ber) and 8-acetonyl-dihydroberberine (A-Ber) alone and combined uses with antibacterial agents ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) was studied on 10 clinical isolates of SCCmec III type methicillin-resistant Staphylococcus aureus (MRSA). Susceptibility to each agent alone was tested using a broth microdilution method and the chequerboard and time-kill tests for the combined evaluations, respectively. The alone MICs/MBCs (μg/mL) ranges were 32-128/64-256 (Ber) and 32-128/128-512 (A-Ber). Significant synergies were observed for the Ber (A-Ber)/AZM and Ber (A-Ber)/LEV combinations against 90% of the tested MRSA strains, with fractional inhibitory concentration indices (FICIs) values ranged from 0.188 to 0.500. An additivity result was also observed for the Ber/AZM combination by time-kill curves. These results demonstrated for the first time that Ber and A-Ber enhanced the in vitro inhibitory efficacy of AZM and LEV to a same extent, which had potential for further investigation in combinatory therapeutic applications of patients infected with MRSA.

  2. Comparison of Neisseria gonorrhoeae MICs Obtained by Etest and Agar Dilution for Ceftriaxone, Cefpodoxime, Cefixime and Azithromycin.

    Science.gov (United States)

    Gose, Severin; Kong, Carol J; Lee, Yer; Samuel, Michael C; Bauer, Heidi M; Dixon, Paula; Soge, Olusegun O; Lei, John; Pandori, Mark

    2013-10-24

    We evaluated Neisseria gonorrhoeae Etest minimum inhibitory concentrations (MICs) relative to agar dilution MICs for 664 urethral isolates for ceftriaxone (CRO) and azithromycin (AZM), 351 isolates for cefpodoxime (CPD) and 315 isolates for cefixime (CFM). Etest accurately determined CPD, CFM and AZM MICs, but resulted in higher CRO MICs. © 2013. Published by Elsevier B.V. All rights reserved.

  3. The role of microRNAs in the pathogenesis of MMPi-induced skin fibrodysplasia

    Science.gov (United States)

    2013-01-01

    Background Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes involved in extracellular matrix (ECM) homeostasis. MMPs have been an attractive pharmacological target for a number of indications. However, development has been hampered by the propensity of compounds targeting these enzymes to cause connective-tissue pathologies. The broad-spectrum MMP-inhibitor (MMPi) AZM551248 has been shown to induce such effects in the dog. Histopathological changes were consistent with fibrodysplasia (FD), characterised by fibroblast proliferation and the deposition of collagen in the subcutaneous tissues. We conducted a time-course study administering 20mg/kg/day AZM551248 between 4 and 17 days. Cervical subcutaneous tissue and plasma were sampled during the time-course. miRNA expression profiles in subcutaneous skin specimens following the administration of AZM551248 were determined by high-throughput-sequencing. Results An increasing number of miRNAs were differentially expressed compared with vehicle treated control animals as the study progressed. Several of these were members of the miR-200 family and were significantly attenuated in response to MMPi. As the severity of FD increased at the later time-points, other miRNAs associated with TGFβ synthesis and regulation of the acute inflammatory response were modulated. Evidence indicative of epithelial to mesenchymal transition was present at all study time points. Receiver operator curve (ROC) analysis revealed that miR-21 expression in the cervical subcutaneous tissue was a sensitive and specific biomarker of FD incidence. Conclusions Our data reveal significant perturbations in canine skin miRNA expression in response to MMPi administration. Furthermore, we have identified dysregulated miRNAs that are associated with processes relevant to the key histopathological events of MMPi-induced FD. PMID:23688202

  4. Work characteristics and pesticide exposures among migrant agricultural families: a community-based research approach.

    Science.gov (United States)

    McCauley, L A; Lasarev, M R; Higgins, G; Rothlein, J; Muniz, J; Ebbert, C; Phillips, J

    2001-05-01

    There are few data on pesticide exposures of migrant Latino farmworker children, and access to this vulnerable population is often difficult. In this paper we describe a community-based approach to implement culturally appropriate research methods with a migrant Latino farmworker community in Oregon. Assessments were conducted in 96 farmworker homes and 24 grower homes in two agricultural communities in Oregon. Measurements included surveys of pesticide use and work protection practices and analyses of home-dust samples for pesticide residues of major organophosphates used in area crops. Results indicate that migrant farmworker housing is diverse, and the amounts and types of pesticide residues found in homes differ. Azinphos-methyl (AZM) was the pesticide residue found most often in both farmworker and grower homes. The median level of AZM in farmworker homes was 1.45 ppm compared to 1.64 ppm in the entry area of grower homes. The median level of AZM in the play areas of grower homes was 0.71 ppm. The levels of AZM in migrant farmworker homes were most associated with the distance from fields and the number of agricultural workers in the home. Although the levels of AZM in growers and farmworker homes were comparable in certain areas, potential for disproportionate exposures occur in areas of the homes where children are most likely to play. The relationship between home resident density, levels of pesticide residues, and play behaviors of children merit further attention.

  5. Issues concerning gravity waves from first-order phase transitions

    International Nuclear Information System (INIS)

    Kosowsky, A.

    1993-01-01

    The stochastic background of gravitational radiation is a unique and potentially valuable source of information about the early universe. Photons thermally decoupled when the universe was around 100,000 years old; electromagnetic radiation cannot directly provide information about the epoch earlier than this. In contrast, gravitons presumably decoupled around the Planck time, when the universe was only 10 -44 seconds old. Since gravity wave propagate virtually unimpeded, any energetic event in the evolution of the universe will leave an imprint on the gravity wave background. Turner and Wilczek first suggested that first-order phase transitions, and particularly transitions which occur via the nucleation, expansion, and percolation of vacuum bubbles, will be a particularly efficient source of gravitational radiation. Detailed calculations with scalar-field vacuum bubbles confirm this conjecture and show that strongly first-order phase transitions are probably the strongest stochastic gravity-wave source yet conjectured. In this work the author first reviews the vacuum bubble calculations, stressing their physical assumptions. The author then discusses realistic scenarios for first-order phase transitions and describes how the calculations must be modified and extended to produce reliable results. 11 refs

  6. Antibacterial and Synergy of Berberines with Antibacterial Agents against Clinical Multi-Drug Resistant Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA

    Directory of Open Access Journals (Sweden)

    Zhong-Qi Bian

    2012-08-01

    Full Text Available Antibacterial activity of berberine (Ber and 8-acetonyl-dihydroberberine (A-Ber alone and combined uses with antibacterial agents ampicillin (AMP, azithromycin (AZM, cefazolin (CFZ and levofloxacin (LEV was studied on 10 clinical isolates of SCCmec III type methicillin-resistant Staphylococcus aureus (MRSA. Susceptibility to each agent alone was tested using a broth microdilution method and the chequerboard and time-kill tests for the combined evaluations, respectively. The alone MICs/MBCs (mg/mL ranges were 32–128/64–256 (Ber and 32-128/128-512 (A-Ber. Significant synergies were observed for the Ber (A-Ber/AZM and Ber (A-Ber/LEV combinations against 90% of the tested MRSA strains, with fractional inhibitory concentration indices (FICIs values ranged  from 0.188 to 0.500. An additivity result was also observed for the Ber/AZM combination by time-kill curves. These results demonstrated for the first time that Ber and A-Ber enhanced the in vitro inhibitory efficacy of AZM and LEV to a same extent, which had potential for further investigation in combinatory therapeutic applications of patients infected with MRSA.

  7. Energy transition and phasing out nuclear

    International Nuclear Information System (INIS)

    Laponche, Bernard

    2013-05-01

    In the first part of this report, the author outlines and comments the need of an energy transition in the world: overview of world challenges (world energy consumption and its constraints, a necessary energy transition, new actors and new responsibilities), and describes the German example of an energy transition policy. In the second part, he presents and discusses the main reasons for phasing out nuclear: description of a nuclear plant operation (fission and chain reaction, heat production, production of radioactive elements, how to stop a nuclear reactor), safety and risk issues (protection arrangements, risk and consequence of a nuclear accident), issue of radioactive wastes, relationship between civil techniques and proliferation of nuclear weapons. In a third part, the author proposes an overview of the energy issue in France: final energy consumption, electricity production and consumption, primary energy consumption, characteristics of the French energy system (oil dependency, electricity consumption, and high share of nuclear energy in electricity production). In a last part, the author addresses the issue of energy transition in a perspective of phasing out nuclear: presentation of the Negawatt scenario, assessments made by Global Chance, main programmes of energy transition

  8. Effects of antibiotics on quorum sensing in pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Skindersø, Mette Elena; Alhede, Morten; Phipps, Richard Kerry

    2008-01-01

    in animal infection models. Treatment of cystic fibrosis (CF) patients chronically infected with P. aeruginosa with the macrolide antibiotic azithromycin (AZM) has been demonstrated to improve the clinical outcome. Several studies indicate that AZM may accomplish its beneficial action in CF patients....... Three of the antibiotics tested, AZM, ceftazidime (CFT), and ciprofloxacin (CPR), were very active in the assay and were further examined for their effects on QS-regulated virulence factor production in P. aeruginosa. The effects of the three antibiotics administered at subinhibitory concentrations were...... by impeding QS, thereby reducing the pathogenicity of P. aeruginosa. This led us to investigate whether QS inhibition is a common feature of antibiotics. We present the results of a screening of 12 antibiotics for their QS-inhibitory activities using a previously described QS inhibitor selector 1 strain...

  9. AcEST: DK958823 [AcEST

    Lifescience Database Archive (English)

    Full Text Available MPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 ...p|Q68749|POLG_HCVBB Genome polyprotein OS=Hepatitis C virus gen... 33 0.98 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched sna...kehead... 31 4.8 sp|Q7XWS7|FH12_ORYSJ Formin-like protein 12 OS=Oryza sativa subs..

  10. Department of Labor Issues. Transition Series.

    Science.gov (United States)

    Comptroller General of the U.S., Washington, DC.

    The Secretary of Labor should place emphasis on five issues to ensure safe and healthful workplaces and to promote the welfare of wage earners. First, the Secretary should improve the Occupational Safety and Health Administration's enforcement program. Second, the Secretary should enhance the use of Job Training Partnership Act resources. Third,…

  11. Public Policies for Career Development. Case Studies And Emerging Issues For Designing Career Information And Guidance Systems In Developing And Transition Economies

    Science.gov (United States)

    Watts, A. G.; Fretwell, David H.

    2004-01-01

    The following pages summarize the findings of seven case-studies of public policy in career guidance carried out in Chile, the Philippines, Poland, Romania, Russia, South Africa and Turkey. The objectives of this World Bank study were: to identify and describe the distinctive issues faced by developing and transition economies in forming effective…

  12. Rethinking Healthcare Transitions and Policies: Changing and Expanding Roles in Transitional Care

    Science.gov (United States)

    Moreño, Patricienn K.

    2014-01-01

    The breakdown of care transitions between various healthcare facilities, providers, and services is a major issue in healthcare, and accounts for over US$15 billion in healthcare expenditures annually. The transition between inpatient care and home care is a very delicate period where, too often, chronically ill patients get worse and wind up back…

  13. Energy access and transition to cleaner cooking fuels and technologies in Sri Lanka: Issues and policy limitations

    International Nuclear Information System (INIS)

    Wickramasinghe, Anoja

    2011-01-01

    Easy energy access is a trigger for human, social, and economic development. A research project was undertaken in Sri Lanka to broaden the understanding of human dimension of energy access and technologies. A questionnaire survey, covering 2269 households, gathered data on socio-economic contexts and issues influencing a transition towards clean cooking facilities. The findings reveal that the transition is impeded by four factors: the lack of motivation and the pressure for switching over to cleaner facilities, the lack of modern energy technology options, the financial risks, and the lack of financing and other support. The paper describes the delicate two-way interrelation between women earning wages and the transitions to cleaner cooking fuels and technologies. The findings suggest the need for a policy framework involving the stakeholders, financing and standardised technologies. To make a change it is proposed to introduce a national, integrated policy incorporating financing and energy governance. - Highlights: ► Households in Sri Lanka lack access to modern energy technology options for cooking. ► Cooking with fuel wood and residues is the norm in Sri Lanka, particularly in rural households. ► A survey of rural households revealed that most cannot afford to switch to cleaner cooking options. ► Most households have little awareness of the health impacts of biomass cooking. ► Women in regular formal employment are more likely to value cleaner cooking options that save time.

  14. Transition and Social networks

    OpenAIRE

    Raghavan, Raghu; Pawson, N.

    2011-01-01

    School leavers with learning disabilities often face difficulties in making a smooth transition from school to college, employment or more broadly, to adult life. The transition phase is traumatic for the young person with learning disabilities and their families as it often results in the loss of friendships, relationships and social networks. The aim of this chapter is to explore the issues of transition from adolescence to adulthood for young people with learning disabilities and its effe...

  15. Transition to a hydrogen fuel cell transit bus fleet for Canadian urban transit system

    International Nuclear Information System (INIS)

    Ducharme, P.

    2004-01-01

    'Full text:' The Canadian Transportation Fuel Cell Alliance (CTFCA), created by the Canadian Government as part of its 2000 Climate Change Action Plan, has commissioned MARCON-DDM's Hydrogen Intervention Team (HIT) to provide a roadmap for urban transit systems that wish to move to hydrogen fuel cell-powered bus fleets. HIT is currently in the process of gathering information from hydrogen technology providers, bus manufacturers, fuelling system providers and urban transit systems in Canada, the US and Europe. In September, HIT will be in a position to provide a preview of its report to the CTFCA, due for October 2004. The planned table of contents includes: TOMORROW'S FUEL CELL (FC) URBAN TRANSIT BUS - Powertrain, on-board fuel technologies - FC engine system manufacturers - Bus technical specifications, performances, operating characteristics - FC bus manufacturers TOMORROW'S FC TRANSIT PROPERTY - Added maintenance, facilities and fuelling infrastructure requirements - Supply chain implications - Environmental and safety issues - Alternative operational concepts PATHWAYS TO THE FUTURE - Choosing the future operational concept - 'Gap' assessment - how long from here to there? - Facilities and fleet adjustments, including fuelling infrastructure - Risk mitigation, code compliance measures TRANSITIONAL CONSIDERATIONS - Cost implications - Transition schedule (author)

  16. A programme in transition

    International Nuclear Information System (INIS)

    Dean, S.O.

    1992-01-01

    Fusion is beginning its transition from a scientific research programme to that of an engineering development programme aimed at practical applications. This transition is likely to last a decade or more because many scientific questions remain and because of the magnitude and cost of the engineering issues. This article reviews briefly the encouraging results produced at the Joint European Torus (JET) where 1.7 MW of fusion power was generated for 2 seconds in experiments in November 1991, the remaining scientific issues, the role of near-term experimental reactors like the International Thermonuclear Experimental reactor (ITER) and other approaches to a demonstration power plant. (author)

  17. Strengthening national coal transitions to raise climate ambition. Issue Brief. Part of the 'Coal Transitions: Research and Dialogue on the Future of Coal' Project

    International Nuclear Information System (INIS)

    Sartor, Oliver

    2017-11-01

    The issue of coal transitions is coming into focus in both national and international climate policy discussions. There are several drivers of this. At one level, the Paris Agreement marked a significant shift in the pace, scope and ambition of global climate change mitigation action. Consequently, it is now clear that coal will need to play a more and more diminished role in the global energy mix in the coming decades, despite carbon capture and storage (CCS) technologies. It is also increasingly clear that non-climate policy-related factors, such as rapid declines in the cost of renewable energy and battery storage, will continue to challenge the previously strong role of steam coal in the global energy mix (Randall, 2015). The business-as-usual scenario is therefore evolving quickly and the downside risks to coal demand appear to be increasing. The accumulation of these factors has in turn led to a call for an assurance of 'just transition', especially from stakeholders-notably coal sector workers and their communities-whose economic livelihoods depend on the future of an industry that will be in decline. In this context, parties to the UNFCCC will be called upon via the Facilitative Dialogue of 2018 to re-evaluate the adequacy progress and subsequently to revise their levels of ambition in their nationally determined contributions (NDCs). This moment presents an important opportunity for governments to raise the overall ambition of their policies on coal transition. But how should they do this? (author)

  18. Energy and population: transitional issues and eventual limits.

    Science.gov (United States)

    Werbos, P J

    1990-08-01

    The implication of population size for US energy requirements is explored in this essay. The basic argument is that the present supply of fuels and energy technologies is not sustainable in the long run, that a wide range of choices is possible when a complete transition is made to sustainable technologies, and that the growth of population and the composition of this growth during the next 30 years are the most serious problems impacting on the achievement of sustainable technology. The importance and future of fuel oil is discussed as well as the transition to sustainable energy supplies: conservation, renewables, nuclear and coal. Dependency on oil can only be changed through time and the infusion of money, but even with these givens, the transition is also dependent on the political and budgetary climate. The race is between crisis and cure. It is argued that the soft energy systems (biomass, solar water heater, wind, hydro, and geothermal energy) along with conservation will increase easily and naturally, but the total potential from these sources amounts to only 10% of the present US energy supply. Conservation offers greater hope because 80% of end-use fossil fuel is used in transportation and industry. Further growth of the population in the US would create a demand to desalinate water, which would increase the demand for energy. A totally soft energy economy is probably not feasible without a drastic reduction in US population. The expected direction is in the increased use of coal, and then nuclear energy. Unfortunately, coal contributes to greenhouse warming, and the supply is limited to 60-100 years. Nuclear proliferation and terrorism is connected to the widespread use of nuclear energy. Some breakthrough technology with cold fusion may offer a safer alternative. High technology renewables such as solar cells can be competitive with nuclear energy, if prices can be kept down. on earth or in space, are being investigated. Exploring a variety of advanced

  19. Transitioning Adolescents and Young Adults With HIV Infection to Adult Care: Pilot Testing the "Movin' Out" Transitioning Protocol.

    Science.gov (United States)

    Maturo, Donna; Powell, Alexis; Major-Wilson, Hannah; Sanchez, Kenia; De Santis, Joseph P; Friedman, Lawrence B

    2015-01-01

    Advances in care and treatment of adolescents/young adults with HIV infection have made survival into adulthood possible, requiring transition to adult care. Researchers have documented that the transition process is challenging for adolescents/young adults. To ensure successful transition, a formal transition protocol is needed. Despite existing research, little quantitative evaluation of the transition process has been conducted. The purpose of the study was to pilot test the "Movin' Out" Transitioning Protocol, a formalized protocol developed to assist transition to adult care. A retrospective medical/nursing record review was conducted with 38 clients enrolled in the "Movin' Out" Transitioning Protocol at a university-based adolescent medicine clinic providing care to adolescents/young adults with HIV infection. Almost half of the participants were able to successfully transition to adult care. Reasons for failure to transition included relocation, attrition, lost to follow-up, and transfer to another adult service. Failure to transition to adult care was not related to adherence issues, X(2) (1, N=38)=2.49, p=.288; substance use, X(2) (1, N=38)=1.71, p=.474; mental health issues, X(2) (1, N=38)=2.23, p=.322; or pregnancy/childrearing, X(2) (1, N=38)=0.00, p=.627). Despite the small sample size, the "Movin' Out" Transitioning Protocol appears to be useful in guiding the transition process of adolescents/young adults with HIV infection to adult care. More research is needed with a larger sample to fully evaluate the "Movin' Out" Transitioning Protocol. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. A sensitive LC-MS/MS method for measurement of organophosphorus pesticides and their oxygen analogs in air sampling matrices.

    Science.gov (United States)

    Armstrong, Jenna L; Dills, Russell L; Yu, Jianbo; Yost, Michael G; Fenske, Richard A

    2014-01-01

    A rapid liquid chromatography tandem mass spectrometry (LC-MS/MS) method has been developed for determination of levels of the organophosphorus (OP) pesticides chlorpyrifos (CPF), azinphos methyl (AZM), and their oxygen analogs chlorpyrifos-oxon (CPF-O) and azinphos methyl-oxon (AZM-O) on common active air sampling matrices. XAD-2 resin and polyurethane foam (PUF) matrices were extracted with acetonitrile containing stable-isotope labeled internal standards (ISTD). Analysis was accomplished in Multiple Reaction Monitoring (MRM) mode, and analytes in unknown samples were identified by retention time (±0.1 min) and qualifier ratio (±30% absolute) as compared to the mean of calibrants. For all compounds, calibration linearity correlation coefficients were ≥0.996. Limits of detection (LOD) ranged from 0.15-1.1 ng/sample for CPF, CPF-O, AZM, and AZM-O on active sampling matrices. Spiked fortification recoveries were 78-113% from XAD-2 active air sampling tubes and 71-108% from PUF active air sampling tubes. Storage stability tests also yielded recoveries ranging from 74-94% after time periods ranging from 2-10 months. The results demonstrate that LC-MS/MS is a sensitive method for determining these compounds from two different matrices at the low concentrations that can result from spray drift and long range transport in non-target areas following agricultural applications. In an inter-laboratory comparison, the limit of quantification (LOQ) for LC-MS/MS was 100 times lower than a typical gas chromatography-mass spectrometry (GC-MS) method.

  1. Financial system development in transition economies

    NARCIS (Netherlands)

    Hermes, C.L.M.; Lensink, B.W.

    This paper provides an overview of the major issues with respect to financial system development in transition economies, which were discussed at a conference in Groningen, the Netherlands, December 1997. After a brief remark on the role of financial system design during economic transition, the

  2. Countermeasures to cope with issues for the FBR cycle system and transitional core during FBR introductory period

    International Nuclear Information System (INIS)

    Fujimura, Koji; Sasahira, Akira; Yamashita, Junichi; Fukasawa, Tetsuo; Hoshino, Kuniyoshi

    2007-01-01

    The introduction of fast breeder reactors (FBRs) requires Pu be recovered from light water reactors (LWRs) spent fuel. The 'Flexible Fuel Cycle Initiative (FFCI)' can supply enough Pu and holds no surplus Pu, while responding flexibly to future technical and social uncertainties. In this paper, the potential of FFCI to increase economy of the fuel cycle system was investigated. On the other hand, during the FBR introductory period, Pu from LWR spent fuel is used for startup of FBRs. But the FBR core being loaded with Pu from LWR spent fuel has a larger burnup reactivity than the core being loaded with Pu from the FBR multi-recycling core. The increased burnup reactivity may reduce the cycle length of the FBR core. In this paper, an FBR transitional core concept to handle the issues of the FBR introductory period was investigated. The results obtained through this study are as follows. (1) The FFCI has a potential to flatten the reprocessing amount of LWR spent fuel and to increase economy of the next fuel cycle system. (2) Minor actinides - mixed FBR transitional core has a potential to maintain the operation cycle length even supposing use of Pu from LWR spent fuel. (author)

  3. Transition issues in an unbundled residential market

    International Nuclear Information System (INIS)

    Brett, J.D.

    1996-01-01

    Aspects of an unbundled residential gas market were discussed, among them (1) the role of a local distribution company (LDC), (2) the context and the issues, (3) the customers'needs and desires, (4) long term planning responsibility, (5) consumer protection and dealing with abuses, (6) the obligation to serve, (7) the bad credit risk customer, (8) billing, credit and collection, and (9) metering and CIS

  4. Health system strategies supporting transition to adult care.

    Science.gov (United States)

    Hepburn, Charlotte Moore; Cohen, Eyal; Bhawra, Jasmin; Weiser, Natalie; Hayeems, Robin Z; Guttmann, Astrid

    2015-06-01

    The transition from paediatric to adult care is associated with poor clinical outcomes, increased costs and low patient and family satisfaction. However, little is known about health system strategies to streamline and safeguard care for youth transitioning to adult services. Moreover, the needs of children and youth are often excluded from broader health system reform discussions, leaving this population especially vulnerable to system 'disintegration'. (1) To explore the international policy profile of paediatric-to-adult care transitions, and (2) to document policy objectives, initiatives and outcomes for jurisdictions publicly committed to addressing transition issues. An international policy scoping review of all publicly available government documents detailing transition-related strategies was completed using a web-based search. Our analysis included a comparable cohort of nine wealthy Organisation for Economic Co-operation and Development (OECD) jurisdictions with Beveridge-style healthcare systems (deemed those most likely to benefit from system-level transition strategies). Few jurisdictions address transition of care issues in either health or broader social policy documents. While many jurisdictions refer to standardised practice guidelines, a few report the intention to use powerful policy levers (including physician remuneration and non-physician investments) to facilitate the uptake of best practice. Most jurisdictions do not address the policy infrastructure required to support successful transitions, and rigorous evaluations of transition strategies are rare. Despite the well-documented risks and costs associated with a poor transition from paediatric to adult care, little policy attention has been paid to this issue. We recommend that healthcare providers engage health system planners in the design and evaluation of system-level, policy-sensitive transition strategies. Published by the BMJ Publishing Group Limited. For permission to use (where not

  5. Turner syndrome--issues to consider for transition to adulthood.

    Science.gov (United States)

    Lucaccioni, Laura; Wong, Sze Choong; Smyth, Arlene; Lyall, Helen; Dominiczak, Anna; Ahmed, S Faisal; Mason, Avril

    2015-03-01

    Turner syndrome (TS) is associated with a spectrum of health problems across the age span, which requires particular attention during the transition period in these adolescents. The majority of girls with TS require oestrogen replacement from puberty onwards, which is important for adequate feminization, uterine development and maintenance of bone health. There is a lifetime increased risk from autoimmune conditions like hypothyroidism, coeliac disease, hearing loss and aortic dilatation with the potential to lead to aortic dissection. A systematic and holistic approach to provision of health care in TS is needed. Several unanswered questions remain, including the choice of hormone replacement therapy in the young person with TS and in adulthood; the optimal mode of cardiovascular assessment; the best management and assessment prior to and during pregnancy. The optimal model of care and transition to adult services in TS requires attention. Further research is needed in relation to cardiovascular risk assessment, pregnancy management and hormone replacement therapy in TS. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Brief Approach to Fundamental Issues Regarding Transitional Justice. Focus on Certain Particularities of Taxable Sanctions within the Special Jurisdiction for Peace

    Directory of Open Access Journals (Sweden)

    Luisa Fernanda Caldas Botero

    2016-06-01

    Full Text Available This document exposes different trains of thought regarding legal issues as a result of the peace agreement reached by the National Government and farc-ep (Revolutionary Armed Forces of Colombia-People’s Army. The paper shows a detailed analysis in regards of the punishments applied in transitional justice, the differente theories regarding punishment and their application to the agreement reached by both parties, seeking to establish if the agreed is congruent with international agreements and the Constitution.

  7. Metal-insulator transitions

    Science.gov (United States)

    Imada, Masatoshi; Fujimori, Atsushi; Tokura, Yoshinori

    1998-10-01

    Metal-insulator transitions are accompanied by huge resistivity changes, even over tens of orders of magnitude, and are widely observed in condensed-matter systems. This article presents the observations and current understanding of the metal-insulator transition with a pedagogical introduction to the subject. Especially important are the transitions driven by correlation effects associated with the electron-electron interaction. The insulating phase caused by the correlation effects is categorized as the Mott Insulator. Near the transition point the metallic state shows fluctuations and orderings in the spin, charge, and orbital degrees of freedom. The properties of these metals are frequently quite different from those of ordinary metals, as measured by transport, optical, and magnetic probes. The review first describes theoretical approaches to the unusual metallic states and to the metal-insulator transition. The Fermi-liquid theory treats the correlations that can be adiabatically connected with the noninteracting picture. Strong-coupling models that do not require Fermi-liquid behavior have also been developed. Much work has also been done on the scaling theory of the transition. A central issue for this review is the evaluation of these approaches in simple theoretical systems such as the Hubbard model and t-J models. Another key issue is strong competition among various orderings as in the interplay of spin and orbital fluctuations. Experimentally, the unusual properties of the metallic state near the insulating transition have been most extensively studied in d-electron systems. In particular, there is revived interest in transition-metal oxides, motivated by the epoch-making findings of high-temperature superconductivity in cuprates and colossal magnetoresistance in manganites. The article reviews the rich phenomena of anomalous metallicity, taking as examples Ti, V, Cr, Mn, Fe, Co, Ni, Cu, and Ru compounds. The diverse phenomena include strong spin and

  8. Clinical efficacy of subgingivally delivered 0.5% controlled release azithromycin gel in the management of chronic periodontitis.

    Science.gov (United States)

    Tyagi, Prashant; Vaish, Shubhra; Dodwad, Vidya

    2011-06-01

    Recent developments suggest that the local delivery of antimicrobials into periodontal pockets can improve periodontal health. Azithromycin (AZM) has a wide antimicrobial spectrum of action toward anaerobic bacteria as well as Gram-negative bacilli. It is effective against periodontal pathogens such as Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Therefore, this study was undertaken to investigate the clinical effectiveness of AZM at 0.5% concentration in an indigenously prepared bioabsorbable controlled release gel as an adjunct to non-surgical mechanical therapy in the treatment of chronic periodontitis. Thirty sites in patients with chronic periodontitis and probing depth (PD) 4-6 mm were categorized randomly into two treatment groups: Scaling and root planing (SRP) plus 0.5% AZM gel (group 1) and SRP only (group 2). Clinical evaluation was undertaken using the Gingival Index (GI) of Loe and Silness and plaque was assessed using the Turesky et al. modification of Quigley Hein Index at baseline and 21 days. Pocket PD and clinical attachment level (CAL) were also measured. Results were expressed as mean±standard deviation and percentages and the data were analyzed using Statistical Package for Social Sciences (SPSS version 16.0, SPSS, Chicago, IL) software. Both therapies resulted in significant improvements. Mean reduction in GI from baseline to 21 days was 1.20±0.41 and 0.73±0.45 in group 1 and group 2, respectively. Plaque Index also improved through the study period in both groups, i.e., 0.86±0.51 in group 1 and 1.6±0.97 in group 2. Mean PD reduced significantly with SRP plus AZM gel application in group 1, i.e., 2.1±0.91 mm as compared to 1.0±1.06 mm achieved with SRP alone. A significant gain in mean CAL gain was observed in the test group (1.8±0.63 mm) as compared to control group (1.0±1.06 mm). Although both treatment strategies seem to benefit patients, the adjunctive use of 0.5% of AZM showed significant results.

  9. Menopause: A Life Cycle Transition.

    Science.gov (United States)

    Evarts, Barbara Kess; Baldwin, Cynthia

    1998-01-01

    Family therapists need to address the issue of menopause proactively to be of benefit to couples and families during this transitional period in the family life cycle. Physical, psychological, and psychosocial factors affecting the menopausal woman and her family, and ways to address these issues in counseling are discussed. (Author/EMK)

  10. Food control concept: Food safety/ingestion issues

    International Nuclear Information System (INIS)

    Armstrong, B.

    1995-01-01

    This talk outlines the issues in food safety/ingestion in the case of radiation accidents at nuclear power plants and how emergency preparedness plans can/should be tailored. The major topics are as follows: In Washington: food safety/ingestion issues exist at transition between response and regulatory worlds; agricultural concerns; customer concerns; Three Mile Island: detailed maps; development of response procedures; development of tools; legal issues

  11. Transition(s) towards an ecologic economy. The prospective program

    International Nuclear Information System (INIS)

    Riviere, Antoine; Hervieu, Halvard; Monnoyer-Smith, Laurence; Cecutti-Etahiri, Nathalie

    2015-07-01

    This publication aims at presenting works performed between 2010 and 2014 within the frame of the prospective program 'Transition(s) towards an ecologic economy' of the prospective mission of the CGDD (Commissariat General au Developpement Durable, the French General Committee for Sustainable Development). It also presents lessons which can be learned. The first part examines what could be the shape of an ecologic economy. For this purpose, scenarios have been developed which allow the role which various actors (citizen, territories, State) can play, and the possible evolutions of the present social-economic system to be explored. The second part addresses more specific issues in order to highlight some levers of action for a successful transition. These issues can be transverse (for example, the role of ITs in ecologic economy, or the human factor in terms of challenge of social change and employment) as well as sector-based (focus on transports and on ecologic mobility in the perspective of automotive industries and enterprises, and of public policies)

  12. Chalk Catchment Transit Time: Unresolved Issues

    Energy Technology Data Exchange (ETDEWEB)

    Darling, W. G.; Gooddy, D. C. [British Geological Survey, Crowmarsh Gifford, Wallingford, Oxfordshire (United Kingdom); Barker, J. A. [School of Civil Engineering and the Environment, University of Southampton, Southampton (United Kingdom); Robinson, M. [Centre for Ecology and Hydrology, Crowmarsh Gifford, Wallingford, Oxfordshire (United Kingdom)

    2013-07-15

    The mean transit time (MTT) of a catchment is the average residence time of water from rainfall to river outflow at the foot of the catchment. As such, MTT has important water quality as well as resource implications. Many catchments worldwide have been measured for MTT using environmental isotopes, yet the Chalk, an important aquifer in NW Europe, has received little attention in this regard. The catchment of the River Lambourn in southern England has been intermittently studied since the 1960s using isotopic methods. A tritium peak measured in the river during the 1970s indicates an apparent MTT of {approx}15 years, but the thick unsaturated zone (average {approx}50 m) of the catchment suggests that the MTT should be much greater because of the average downward movement through the Chalk of {approx}1 m/a consistently indicated by tritium and other tracers. Recent work in the catchment using SF{sub 6} as a residence time indicator has given groundwater ages in the narrow range 11-18 yrs, apparently supporting the river tritium data but in conflict with the unsaturated zone data even allowing for a moderate proportion of rapid bypass flow. The MTT of the catchment remains unresolved for the time being. (author)

  13. Volume 8 Issue 2

    Directory of Open Access Journals (Sweden)

    Karen Nelson

    2017-06-01

    Full Text Available This issue is our third Students, Transitions, Achievement, Retention and Success (STARS Conference special issue held in July this year in Adelaide, Australia.   As is customary, this issue of the journal publishes the top research papers selected via a peer review process and the top Emerging Initiatives selected by the Conference Committee.    We are delighted to feature in this special  issue —Reflections on Student Persistence—prepared by Advisory Board member Professor Vincent Tinto, Distinguished University Professor Emeritus at Syracuse University, USA.  Vincent is a long-time friend and supporter of STARS and its predecessor FYHE Conferences and Journal.   In his article, Vincent explores the case for motivation to be considered as a significant aspect of the tertiary student psyche by drawing on theoretical frameworks, research and practical experiences related to the issue.

  14. The role of transit in the economy of Latvia

    Directory of Open Access Journals (Sweden)

    Gžibovska Nataļja

    2013-06-01

    Full Text Available Transit is an important issue in the history of world economy, including the economy of Latvia. Transit makes a significant contribution to the budget of many transit countries, one of which is the Republic of Latvia. These countries do not have significant natural resources and prefer to focus on logistics and infrastructure in order to facilitate the transit process. This article focuses on the role of transit in the economy of Latvia, whose unique geographical position makes the country an effective transport corridor (bridge in both the west-east and north-south directions. The article presents the results of an opinion poll conducted at Latvian transit enterprises regarding their future development and offers an overview of the main seaports and the Rīga international airport. The author examines the issue of Russia’s accession to the World Trade Organization and its impact on the Latvian transit, the prolongation of EU sanctions against Belarus, and the use of Latvian transport infrastructure for handling the non-military cargo traffic to/from Afghanistan. In conclusion, a forecast of possible transit development in Latvia is provided.

  15. Theoretical Issues

    Energy Technology Data Exchange (ETDEWEB)

    Marc Vanderhaeghen

    2007-04-01

    The theoretical issues in the interpretation of the precision measurements of the nucleon-to-Delta transition by means of electromagnetic probes are highlighted. The results of these measurements are confronted with the state-of-the-art calculations based on chiral effective-field theories (EFT), lattice QCD, large-Nc relations, perturbative QCD, and QCD-inspired models. The link of the nucleon-to-Delta form factors to generalized parton distributions (GPDs) is also discussed.

  16. Framing of regimes and transition strategies

    DEFF Research Database (Denmark)

    Jensen, Jens Stissing

    2012-01-01

    This article suggests that transition strategies are always formulated in the context of specific representations of the regime and the challenges it faces. It is argued that the framing of a regime affects the envisioning of transition strategies. An analysis of the current development agenda...... for the housing construction sector in Denmark reveals the relevance and impacts of different regime framings. It is proposed that the ability to cope with framing issues as situated and political processes is at the core of the governance of transitions....

  17. The great debate: Energy transition, it's us

    International Nuclear Information System (INIS)

    2016-09-01

    Published by authorities of the Nantes metropolitan area, this document first comprises a report in two parts. The first one presents a general approach to energy transition, some definitions, an overview of challenges and stakes, and of action levers. It also describes the national and local contexts with their key figures. The second part addresses three issues of the debate on energy transition: which transition for life styles? Which landscapes and new usages? Which citizen and local appropriation of energy from production to consumption? Which innovation opportunities and jobs? A second document is the final report produced by the debate commission. It proposes an assessment of the participation dynamics, an analysis of citizen contributions on the four above-mentioned issues, and recommendations made by the commission declined in 60 actions. Other documents are also provided: periodic publications with various contributions on the various related issues

  18. Proceedings of the European Conferences on the energy transition

    International Nuclear Information System (INIS)

    Vergriete, Patrice; Juppe, Alain; Lechevin, Bruno; Delevoye, Jean-Paul; Ben Naceur, Kamel; Lemmet, Sylvie; Marignac, Yves; Berhault, Gilles; Baupin, Denis; Fremont, Jean-Pierre; Roumet, Claire; Ruedinger, Andreas; Rousset, Sophie; Lechevin, Bruno; Castelain, Damien; Monloubou, Philippe; Sauvage, Edouard; Viveret, Patrick; Marland, Peter; Bouchart, Christiane; Vamberg, Henriette; Watteeuw, Filip; Soubeste, Jean-Marc; Geoffroy, Helene; Couet, Emmanuel; Pellerin, Isabelle; Garnier, Nicolas; Frank, Bo; Bjoerkmarker, Aasa Karlsson; Santais, Beatrice; Roger, Christian; Careme, Damien; Aubry, Christine; Dubbeling, Marielle; Fernandes, Jose Sa; Framond, Alain de; Vansintjan, Dirk; Servais, Olivier; Leclercq, Michel; Poize, Noemie; Sefcovic, Maros; Royal, Segolene; Vincent, Isabelle; Gaudin, Thomas; Bailleul, David; Establie d'Argence, Marie-Pierre; Poncet, Emmanuel

    2016-01-01

    This huge publication contains contributions and sessions of a conference which addressed the following issues: new abilities and professions in the energy sector, perspectives for local and energy policies and for the society after the COP21 and the role of local communities (tools and actions, education, development of cold networks, and so on), a discussion about what happened during the past year with notably the French law for energy transition and a green growth, an overview of the GRHYD demonstrator (the first Power-to-Gas demonstrator in France), how to finance energy transition, how to shift towards a societal transition, sustainable mobility (a city without car made by its inhabitants), urban agriculture as a lever for action for energy transition, the role of citizen in tomorrow's energy, the post-COP21 European, national and local agenda, energy transition and jobs. Workshops and forums related to various aspects related to these issues are also reported

  19. Evolution of pH buffers and water homeostasis in eukaryotes: homology between humans and Acanthamoeba proteins.

    Science.gov (United States)

    Baig, Abdul M; Zohaib, R; Tariq, S; Ahmad, H R

    2018-02-01

    This study intended to trace the evolution of acid-base buffers and water homeostasis in eukaryotes. Acanthamoeba castellanii  was selected as a model unicellular eukaryote for this purpose. Homologies of proteins involved in pH and water regulatory mechanisms at cellular levels were compared between humans and A. castellanii. Amino acid sequence homology, structural homology, 3D modeling and docking prediction were done to show the extent of similarities between carbonic anhydrase 1 (CA1), aquaporin (AQP), band-3 protein and H + pump. Experimental assays were done with acetazolamide (AZM), brinzolamide and mannitol to observe their effects on the trophozoites of  A. castellanii.  The human CA1, AQP, band-3 protein and H + -transport proteins revealed similar proteins in Acanthamoeba. Docking showed the binding of AZM on amoebal AQP-like proteins.  Acanthamoeba showed transient shape changes and encystation at differential doses of brinzolamide, mannitol and AZM.  Conclusion: Water and pH regulating adapter proteins in Acanthamoeba and humans show significant homology, these mechanisms evolved early in the primitive unicellular eukaryotes and have remained conserved in multicellular eukaryotes.

  20. Ethics and the European countries in transition--the past and the future.

    Science.gov (United States)

    Borovecki, Ana; ten Have, Henk; Oreskovic, Stiepan

    2006-01-01

    This paper surveys the situation regarding bioethical issues in the European transitional societies. It aims at exploring past, present and future characteristics of bioethics in the European countries in transitions, analysing similarities, differences and common themes together with the historical development of bioethics. By carefully studying articles published since the early 1990s, one can perceive a number of bioethical issues, varying from specificities for certain countries to similar problems for all transitional European societies. It seems that more than 15 years after the fall of the Berlin Wall, Central and Eastern European societies were able to achieve significant improvements in the development of bioethics. However, looking at the bioethical issues important for European transitional societies, it seems that the invisible wall between eastern and western European societies is still there and that it will take years to remove it.

  1. Transition to the Cloud

    DEFF Research Database (Denmark)

    Hedman, Jonas; Xiao, Xiao

    2016-01-01

    The rising of cloud computing has dramatically changed the way software companies provide and distribute their IT product and related services over the last decades. Today, most software is bought offthe-shelf and distributed over the Internet. This transition is greatly influencing how software...... companies operate. In this paper, we present a case study of an ERP vendor for SMB (small and mediumsize business) in making a transition towards a cloud-based business model. Through the theoretical lens of ecosystem, we are able to analyze the evolution of the vendor and its business network as a whole......, and find that the relationship between vendor and Value-added-Reseller (VAR) is greatly affected. We conclude by presenting critical issues and challenges for managing such cloud transition....

  2. Critical Issues in the Lives of Children and Youth Who Are Deafblind

    Science.gov (United States)

    Nelson, Catherine; Bruce, Susan M.

    2016-01-01

    The coeditors of an "American Annals of the Deaf" special issue on deafblindness introduce readers to critical issues surrounding children and youth who are deafblind. These issues--early identification, communication, social-emotional needs, family and multicultural issues, universal design and assistive technology, transition planning,…

  3. Proceedings of the workshop on transite decontamination dismantlement and recycle/disposal

    International Nuclear Information System (INIS)

    1993-01-01

    On February 3--4, 1993, a workshop was conducted to examine issues associated with the decontamination, dismantlement, and recycle/disposal of transite located at the US Department of Energy Fernald site near Cincinnati, OH. The Fernald Environmental Management Project (FEMP) is a Superfund Site currently undergoing remediation. A major objective of the workshop was to assess the state-of-the-art of transite remediation, and generate concepts that could be useful to the Fernald Environmental Restoration Management Co. (FERMCO) for remediation of transite. Transite is a building material consisting of asbestos fiber and cement and may be radioactively contaminated as a result of past uranium processing operations at the FEMP. Many of the 100 buildings within the former uranium production area were constructed of transite siding and roofing and consequently, over 180,000 m 2 of transite must be disposed or recycled. Thirty-six participants representing industry, academia, and government institutions such as the EPA and DOE assembled at the workshop to present their experience with transite, describe work in progress, and address the issues involved in remediating transite

  4. Why must there be an energy transition?

    International Nuclear Information System (INIS)

    Schwarz, Virginie; Lavergne, Gerard

    2015-01-01

    The energy transition is a response to the environmental and climate issues now facing our planet. It is also a source of growth and jobs, both very important during the current economic slowdown. Far from being a preoccupation of France alone, this transition toward green growth brings together a vast international movement bearing a new awareness by scientists, citizens and their representatives. Accordingly, changes in the 'energy model' are to be made through joint efforts and the reinforced role to be played by citizens and local authorities for the sake of the environment and well-being and with the ambition of addressing the new century's main environmental issues

  5. Issues on Settlement of Final Expenses and Performance Assessment in the Course of Transition: Evidence from China

    OpenAIRE

    L¨¹ Wei; LIU Yusheng

    2006-01-01

    This paper studies the process and the performance of transition with the following logic: transition is an objective process in accordance with the general principles of economic history; the objectivity is embodied in the expected economic and social effects of transition, the profound economic and social changes in the course of transition, and the different problems facing different transitional stages. Transition is, at the same time, a subjective process involving the participation of t...

  6. Energy transition in France

    International Nuclear Information System (INIS)

    Grandjean, Alain

    2014-01-01

    After having recalled the main issues and stakes addressed by the French national debate on energy transition (strategic stakes, priority to a reduction of French energy consumption, options for the evolution of the French energy mix), the author comments the possible evolution of energy prices and of the energy taxing policy (evolution of oil prices, carbon price). In a second part, the author addresses the issue of financing of building and housing renovation. He shows that this operation cannot be only based on financial markets which are not efficient. This means that a public intervention is required, and different solutions are then possible. Some of them seem difficult to implement (creation of money by the central Bank, creation of a public bank which could lend money to private actors), and some others need to be further examined (creation of a financing company for energy transition, use of national savings, simplified circuits for a financing of local projects by local savings, and so on)

  7. Part-time Labor, Work Rules, and Transit Costs

    Science.gov (United States)

    1981-01-01

    This report examines two major issues: (1)the impact of labor union work rules : on bus transit operating costs and (2)the magnitude of cost savings that can be : expected from the use of part-time drivers. These issues are examined within : the cont...

  8. Energy transition, is it now?

    International Nuclear Information System (INIS)

    Combe, Matthieu; Thouverez, Pierre

    2016-06-01

    As French energy policy is now defined for energy transition, the contributions of this publication discuss implemented measures, what new laws will change, and what will be the consequences for industry. A first set of articles thus comments evolutions related to the implementation of energy transition in the building sector, how energy transition wants to get rid of wastage, how energy transition will impact the transport sector (public transports, car-pool and car sharing, bicycle, retail sector, airfields), and outline that President Hollande has fulfilled (nearly) all his commitments. The next article comments changes and critics made by the French constitutional Council on the law for energy transition. The next set of articles comments the results of an ADEME's study on bicycle kilometre allowance, discusses the issue of energy safety, and comments statements made by candidates to the French President election of 2012 on nuclear energy after the Fukushima accident

  9. Practical Observations of the Transit of Venus

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 5. Practical Observations of the Transit of Venus. B S Shyalaja. Classroom Volume 9 Issue 5 May 2004 pp 79-83. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/009/05/0079-0083 ...

  10. Heeding the Rebel Yell: Identification and Communication in Managing Organizational Issues

    Science.gov (United States)

    Collins, McLean

    2005-01-01

    In applying an issue development model, it is suggested that strategic identification and communication of the Colonel Reb issue would have helped the University of Mississippi to smoother transition to a new athletic mascot.

  11. To finance the ecological transition: our analyses and proposals. Contribution to the public consultation on the financing of the ecological transition

    International Nuclear Information System (INIS)

    Azam, Genevieve; Combes, Maxime; Gadrey, Jean; Harribey, Jean-Marie

    2014-01-01

    The financing of ecological transition is a key issue which conditions the nature of the transition and its ecological efficiency, the acceptability of measures with respect to requirements in terms of social justice, and the sustainability of undertaken actions. This publication is an answer to a public consultation launched by the French government with the publication of a White Paper on these issues. The authors first analyse, discuss and criticise the content of the White Paper. For them, it reduces the approach to a normative one, is based on a decoupling between economic growth and use of resources, propagates a technical-scientific illusion, often indicates selective and incomplete data, and addresses the energy issue through a supply-based approach. In the next part, the authors discuss how transition financing is addressed in the White Paper. In the third part, proposals are made according to three main principles: ecological transition is a social, political, and cultural process which must be supported, financed and implemented at all territorial levels; transition can be financed only if it comes with a strict legal framework which will define what is possible and what is not any longer; financing must be conditioned to results in terms of sobriety and of ecological and social efficiency, including the creation, qualification and sustainability of jobs. A set of programmes is also presented with associated measures on energy efficiency and sobriety, on a fair use of common good, on a re-localisation of activities, and a support of international initiatives. Some proposals are also made regarding financing tools

  12. Gas Transit Tariffs in Selected ECT Countries

    International Nuclear Information System (INIS)

    2006-01-01

    One of the strategic aims of the Energy Charter process is to promote and facilitate efficient and uninhibited transit of energy materials and products across the ECT constituency. The Energy Charter process has recently been focusing its attention on the issues related to the transit of natural gas due to the increasing reliance on gas imports into Europe and other regions from more distant sources and across more borders. The transit tariffs (including their levels, structures and associated conditions) are, in addition to the terms of access to the transit infrastructure, one of the key factors affecting the cross-border gas flows. The main objectives of this study are to: review transit tariff methodologies for existing and new gas transit pipeline systems across selected ECT countries; compare transit tariff regimes for gas with those for domestic gas transport in the same countries; and assess the overall consistency of these transit tariffs with main provisions of ECT and draft Transit Protocol. The scope of this study is limited to transit tariffs for natural gas. Furthermore the study does not address the issue of access to gas pipelines which sometimes is a more important hurdle for gas flows than the levels of transit tariffs. Geographically, the study covers the following key gas transit countries: EU-25 plus Switzerland, and Non-EU: Belarus, Bulgaria, Georgia, Morocco, Tunisia, the Russian Federation, and Ukraine. Chapter 3 describes the existing flows of gas trade and transit across the ECT countries and points out potential deviations between physical and contractual flows. Chapter 4 reviews the theoretical approaches used for setting transit tariffs, including: Typical costs for new gas pipelines: construction costs, financing, operation and maintenance costs, country/project risks and their impact on costs; Valuation approaches for existing pipelines; and Treatment of system expansion. Chapter 5 compares the theory and the practice by describing

  13. Strategic policy and the logistics of crude oil transit in Lithuania

    International Nuclear Information System (INIS)

    Pasukeviciute, Irma; Roe, Michael

    2005-01-01

    This paper examines the crude oil transit market in Lithuania and the significant economic and political role played by Russia. Beginning with an analysis of the strategic and political role played by crude oil in Lithuania there follows a discussion of the policies followed by the Lithuanian authorities following independence in 1992 from the Former Soviet Union. A content analysis approach is taken to establishing the main policy issues that dominate the sector. This technique combines both quantitative and qualitative approaches to a review of published material on oil transit in Lithuania and acts as a means of assessing expert opinion on the issues involved. The results from this analysis will be used in developing policy initiatives for the sector. The paper ends with some suggestions for further applications of the techniques used to oil transit policy issues in the region

  14. Healthy Cities and the Transition movement: converging towards ecological well-being?

    Science.gov (United States)

    Patrick, Rebecca; Dooris, Mark; Poland, Blake

    2016-03-01

    This commentary identifies similarities, differences and opportunities for synergy and mutual learning between the Healthy Cities and the Transition movements. We outline what we consider to be the 'pressing issues' facing humanity and the planet in the early 21(st) century; consider the extent to which health promotion has engaged with and addressed these issues; compare Healthy Cities and the Transition movement; and conclude by suggesting possibilities for moving forward. © The Author(s) 2015.

  15. Research for the energy transition. The organization of the energy systems

    International Nuclear Information System (INIS)

    2017-01-01

    The volume on research for the energy transition includes contributions to the FVEE annual meeting 2016 concerning the following issues: status and perspectives of the energy transition, key technologies for the energy transition, political boundary conditions, development trends in photovoltaics, components for the energy supply (wind energy, hydrogen technologies, smart bioenergy concept, contribution of the geosphere), grids and storage systems for the energy transition, research network renewable energies.

  16. For a citizen energy transition

    International Nuclear Information System (INIS)

    Geze, Patrick; Bernon, Francoise; Alphandery, Claude; Albizzati, Amandine; Ballandras, Marc; Berland, Olivier; Peullemeulle, Justine; Causse, Laurent; Olivier, Dominique; Damerval, Francois; Lepage, Corinne; Dughera, Jacques; Bouchart, Christiane; Duracka, Nicolas; Ferrari, Albert; Noe, Julien; Soulias, Emmanuel; Gaspard, Albane; Greenwood, Marianne; Guy, Lionel; Kretzschmar, Cyril; Lalu, Delphine; Naett, Caroline; Raguet, Alex; Rouchon, Jean-Philippe; Ruedinger, Andreas; Sautter, Christian; Tudor, Ivan; Vaquie, Pierre-Francois; Vernier, Christophe; Youinou, Jean-Michel; Verny, Emmanuel; Claustre, Raphael; Leclercq, Michel

    2015-09-01

    This publication by a think tank specialised in social and solidarity economy first outlines that energy transition means a transition from the present energy model to a new model based on three pillars: a drastic reduction of energy consumption through sobriety (energy saving, struggle against wastage), an improvement of energy efficiency, and an energy mix based on renewable and sustainable resources. A first part proposes a discussion of what 'citizen' energy transition can be: general framework of energy transition, pioneering examples in Europe, citizen empowerment, importance of a decentralised model which is anchored in territories, general interest as a priority. Each of these issues and aspects is illustrated by examples. Then, as this evolution towards a citizen-based model requires a change of scale, the authors discuss how to involve public authorities and to adapt regulation, how to develop financing tools, how to support the emergence and development of projects, and how to be part of international dynamics. The author then discuss what their think tank can do to accelerate energy transition. Proposals made in the different chapters are then summarized

  17. Governing the transition to renewable energy: A review of impacts and policy issues in the small hydropower boom

    International Nuclear Information System (INIS)

    Kelly-Richards, Sarah; Silber-Coats, Noah; Crootof, Arica; Tecklin, David; Bauer, Carl

    2017-01-01

    The transition to renewable energy technologies raises new and important governance questions. With small hydropower (SHP) expanding as part of renewable energy and climate mitigation strategies, this review assesses its impacts and identifies escalating policy issues. To provide a comprehensive literature review of small hydropower, we evaluated over 3600 articles and policy documents. This review identified four major concerns: (1) confusion in small hydropower definitions is convoluting scholarship and policy-making; (2) there is a lack of knowledge and acknowledgement of small hydropower’s social, environmental, and cumulative impacts; (3) small hydropower’s promotion as a climate mitigation strategy can negatively affect local communities, posing contradictions for climate change policy; and (4) institutional analysis is needed to facilitate renewable energy integration with existing environmental laws to ensure sustainable energy development. For readers interested in small hydropower, we clarify areas of confusion in definition and explain the corresponding impacts for distinct system designs. For a broader readership, we situate small hydropower implementation within international trends of renewable energy development – the contradictory impacts of climate change policy, emerging dynamics in energy finance, and reliance on market mechanisms. Our paper provides a timely contribution to scholarship on small hydropower and the transition to renewable energy. - Highlights: • Confusion in small hydropower definitions is convoluting small hydropower debates. • Small hydropower’s negative impacts are largely overlooked in policy discussions. • Small hydropower exemplifies paradoxical problems with climate change policy. • Policies needed to integrate renewable energy development with national environmental institutions.

  18. Social workers as transition brokers: facilitating the transition from pediatric to adult medical care.

    Science.gov (United States)

    Shanske, Susan; Arnold, Janis; Carvalho, Maria; Rein, Jennifer

    2012-01-01

    Transition from pediatric to adult medical care and the significant psychosocial considerations impacting this developmental process are a primary focus in health care today. Social workers are often the informal brokers of this complex and nuanced process and are uniquely trained to complete biopsychosocial assessments to understand the needs of patients and families and address psychosocial factors. Their extensive knowledge of resources and systems, along with their sophisticated understanding of the relationship issues, family dynamics, cultural implications, and basic person-in-context approach allow for unique collaboration with the health care team, family, and community supports to develop successful transition plans and programs.

  19. Venus Elongation Measurements for the Transit of Venus, using the ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 11. Venus Elongation Measurements for the Transit of Venus, using the Historical Jantar Mantar Observatory. N Rathnasree. Classroom Volume 9 Issue 11 November 2004 pp 46-55 ...

  20. Pediatric Renal Transplantation: Focus on Current Transition Care and Proposal of the "RISE to Transition" Protocol.

    Science.gov (United States)

    Raina, Rupesh; Wang, Joseph; Krishnappa, Vinod; Ferris, Maria

    2018-01-16

    The transition from pediatric to adult medical services is an important time in the life of an adolescent or young adult with a renal transplant. Failure of proper transition can lead to medical non-adherence and subsequent loss of graft and/or return to dialysis. The aim of this study was to conduct a systematic review and survey to assess the challenges and existing practices in transition of renal transplant recipient children to adult services, and to develop a transition protocol. We conducted a literature review and performed a survey of pediatric nephrologists across the United States to examine the current state of transition care. A structured transition protocol was developed based on these results. Our literature review revealed that a transition program has a positive impact on decline in renal function and acute rejection episodes, and may improve long-term graft outcomes in pediatric kidney transplant patients. With a response rate of 40% (60/150) from nephrologists in 56% (49/87) of centers, our survey shows inconsistent use of validated tools despite their availability, inefficient communication between teams, and lack of use of dedicated clinics. To address these issues, we developed the "RISE to Transition" protocol, which relies on 4 competency areas: Recognition, Insight, Self-reliance, and Establishment of healthy habits. The transition program decreases acute graft rejection episodes, and the main challenges in transition care are the communication gap between health care providers and inconsistent use of transition tools. Our RISE to transition protocol incorporates transition tools, defines personnel, and aims to improve communication between teams.

  1. Making existential meaning in transition to motherhood-A scoping review

    DEFF Research Database (Denmark)

    Prinds, Christina; Hvidt, Niels Christian; Mogensen, Ole

    2014-01-01

    the approach of a scoping review. Systematic searches in the electronic databases PubMed, CINAHL and PsycINFO were combined with manual and electronic searches for related references. Studies published between 1990 and 2010 examining dimensions of existential meaning-making in transition to motherhood were......, and to some women also being interpreted as a spiritual experience. However, in present maternity services there is a predominant focus on biomedical issues, which sets the arena for motherhood transition, and the issues related to potentially existentially changing experiences, are not considered important...

  2. The DOE/EM facility transition program

    International Nuclear Information System (INIS)

    Bixby, W.

    1994-01-01

    The mission of EM-60 is to plan, implement, and manage receipt of surplus facilities resulting from downsizing of the DOE Weapons Complex facilities and DOE operating program offices to EM, and to ensure prompt deactivation of such facilities in order to reach a minimum surveillance and maintenance condition. The revised organizational structure of EM-60 into four offices (one at headquarters, and the other three at field sites), reflects increased operating functions associated with deactivation, surveillance, and maintenance of facilities. EM-60's deactivation and transition role concerns technical, socioeconomic, institutional, and administrative issues. The primary objective of the deactivation process is to put facilities in the lowest surveillance and maintenance condition safely and quickly by driving down the open-quotes mortgageclose quotes costs of maintaining them until final disposition. EM-60's three key activities are: (1) Inventory of surplus facilities - The 1993 Surplus Facility Inventory and Assessment (SFIA) serves as a planning tool to help the Department and EM-60 determine optimal transition phasing, with safety and cost-effectiveness remaining a priority. (2) Management of accelerated facility life cycle transition - Transitions currently underway illustrate site issues. These include addressing the interests of federal and state regulatory agencies as well as interests of local stakeholders, safe management of large amounts of production residues, and options for treatment, storage, transportation, and disposal. Of equal importance in the transition process is planning the optimal transition of the labor force. (3) Economic development - to address the socio-economic impacts on affected communities of the severe and rapid downsizing of the DOE Weapons Complex, DOE is pursuing an approach that uses the land, equipment, technology assets, and highly skilled local workforces as a basis for alternative economic development

  3. Democratization and Transitional Justice in Brazil

    Directory of Open Access Journals (Sweden)

    Maria Paula NASCIMENTO ARAUJO

    2016-05-01

    Full Text Available Brazil experienced a long process of political transition featured by an intense game of political and social forces, in which different actors with different democratization projects clashed. Despite the leadership of the transition process have been in the hands of conservative elites linked to the military dictatorship, broad sectors of the oposition and of the lefts, as well as representants of social movements, disputed the transitional space and expanded the initial design of the regime. This long transition —marked by negotiations, frustrations and resilience— reflected on the transitional justice model adopted by the country. Almost 30 years after the end of military dictatorship, the Truth Commission established by President Dilma Rousseff in 2012, drew attention to issues related to memory, justice and reparation and showed that the democratization process, in some respects, is still incloncluded. This article aims to restore this historical process highlighting some of its characteristics and specificities.

  4. Energy transition: which opportunities for the French industry?

    International Nuclear Information System (INIS)

    Bousson, Guillaume; Pouzeratte, Francois; Pierret, Christian; Bensasson, Bruno; Bouttes, Jean-Paul; Bouygues, Olivier; Durdilly, Robert; Geoffron, Patrice; Ladoucette, Philippe de; Lepercq, Thierry; Maillard, Dominique; Rosier, Philippe; Sauquet, Philippe

    2014-05-01

    Regulatory requirements introduced by the new policy of energy transition will force the French industry to look for alternatives to oil and coal. Within this context, this publication contains contributions proposed by industrial and academic experts which aim at discussing how the French industry can seize the opportunity of energy transition to strengthen itself. The authors discuss the issue of competitiveness, the role of de-carbonated electricity, the context of energy transition in France, the evolutions and transformations of the energy market. They also outline the lack of an energy vision in France, the role of the electricity grid as a vector of energy transition, and the fact that the debate on energy transition did not result in concrete solutions

  5. Health care transition for youth living with HIV/AIDS.

    Science.gov (United States)

    Dowshen, Nadia; D'Angelo, Lawrence

    2011-10-01

    There are ~1 million people in the United States living with HIV/AIDS, and >50,000 new infections occur each year. With an estimated 13% of all new infections occurring among young people aged 13 to 24 years and an increasing number of perinatally infected youth surviving to adulthood, there is now an increasing need to transition both perinatally and behaviorally infected youth to the adult health care setting. Recently, pediatric providers and professional societies have prioritized the development of transition programs for adolescents with chronic disease to address the many challenges these youth face in the process. Although multiple position papers have called for continuous, coordinated, culturally appropriate, compassionate, family-centered transition programs for youth with special health care needs and have recognized the need for evidence-based models, few data exist on what strategies are most effective. To date, published data on health care transition for HIV-positive youth are limited and include only 2 studies, which considered behaviorally infected youth. In this state-of-the-art review, we discuss the unique transition challenges to consider for this population, including socioeconomic and health insurance status, the special role of the pediatric or adolescent provider as family, stigma and disclosure issues, cognitive development and mental health issues, medication adherence, and sexual, reproductive, and gender health concerns. Future research will need to include the experiences of transition in low-resource settings and examine clinical outcomes and factors that may predict success or failure of the transition process.

  6. Making existential meaning in transition to motherhood

    DEFF Research Database (Denmark)

    Prinds, Christina Lange; Mogensen, Ole; Hvidt, Niels Christian

    2013-01-01

    living, and to some women also being interpreted as a spiritual experience. However, in present maternity services there is a predominant focus on biomedical issues, which sets the arena for motherhood transition, and the issues related to potentially existentially changing experiences......) outcome measures, and (g) results. Measurements: The studies were synthesised in a thematisation on the basis of the existential psychotherapist and philosopher Emmy van Deurzen's concepts of four interwoven life dimensions, through which we experience, interpret, and act in the world: Umwelt, Mitwelt......, Eigenwelt, and Überwelt. Key conclusions: The findings in this review suggest that transition to motherhood is considered a pivotal and paradoxical life event. Through the lens of existential psychology it can be interpreted as an existentially changing event, reorganising values and what makes life worth...

  7. Transitional Patterns of Adolescent Females in Non-Traditional Career Paths.

    Science.gov (United States)

    Ciccocioppo, Anna-Lisa; Stewin, Leonard L.; Madill, Helen M.; Montgomerie, T. Craig; Tovell, Dorothy R.; Armour, Margaret-Ann; Fitzsimmons, George W.

    2002-01-01

    Examines the factors that affected the career decision-making of adolescent females and young women in undergraduate science, engineering, and technology programs. Qualitative analysis was used to uncover seven themes: transition from high school, educational influences, family influences, academic issues, coursework management, gender issues, and…

  8. ITER ITA newsletter. Special issue - December 2006

    International Nuclear Information System (INIS)

    2006-12-01

    This issue of ITER ITA (ITER transitional arrangements) newsletter contains information about signing ITER Agreement, which took place on 21 November 2006 in Paris, France. It was great day for fusion research as Ministers from the seven ITER Parties in the presence of President Jacques Chirac and President of European Commission Jose Barroso and some 400 invited guests signed the Agreement setting up the ITER International Fusion Energy Organization. This issues contains the speeches, statements and remarks of Presidents and Ministers

  9. Quantum spin-glass transition in the two-dimensional electron gas

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 58; Issue 2 ... Spin glasses; quantum phase transition; ferromagnetism; electron gas. ... We argue that a quantum transition involving the destruction of the spin-glass order in an applied in-plane magnetic field offers a natural explanation of some features of recent ...

  10. French people, energy transition, and energy savings. IFOP for Energie Perspective

    International Nuclear Information System (INIS)

    Fourquet, Jerome; Chasles-Parot, Marion

    2014-10-01

    After a presentation of the adopted methodology, this report presents under the form of tables, and comments the results of a survey performed on the perception and relationship French people have on and with energy transition and energy savings. Different aspects have been addressed and assessed by this survey: confidence in local authorities, recognition of energy transition, sensitivity of the issue of energy transition, an example of a local authority communication about energy issues, notoriety of subsidies and primes awarded by the local authority for energy-related works, assessment of well-being in housing, housing occupation status, intention to perform energy-related renovation works in the housing, choice between a large national group or a local company to perform these works

  11. Ugly Facts and Fancy Theories: Children and Youth during the Transition. Innocenti Occasional Papers Economic Policy Series, Number 47. Special Subseries: Economies in Transition.

    Science.gov (United States)

    Cornia, Giovanni Andrea

    This is a report sponsored by UNICEF on the effects of economic and political transition in Europe, particularly Eastern Europe, on young children and adolescents. The economic theories and changes in labor and markets which have characterized European transitions in the past few years have paid little attention to issues of poverty and child…

  12. Security Issues Model on Cloud Computing: A Case of Malaysia

    OpenAIRE

    Komeil Raisian; Jamaiah Yahaya

    2015-01-01

    By developing the cloud computing, viewpoint of many people regarding the infrastructure architectures, software distribution and improvement model changed significantly. Cloud computing associates with the pioneering deployment architecture, which could be done through grid calculating, effectiveness calculating and autonomic calculating. The fast transition towards that, has increased the worries regarding a critical issue for the effective transition of cloud computing. From the security v...

  13. Assessing and identifying transitional losers and winners in the Serbian society

    Directory of Open Access Journals (Sweden)

    Trifunović Vesna

    2012-01-01

    Full Text Available This paper presents ways to assess and evaluate losers and winners in the Serbian transitional society, through several concrete examples. Therefore, the paper is a follow-up of the manuscript published in the previous Bulletin of Institute of ethnography, and fits into the theoretical framework already stated. The main indicator of a variety of assessment regarding losers and winners is found among comments made by visitors of relevant Internet web sites, referring to news about societal problems and issues during the process of post-socialist transformation. These are directly linked with a phenomenon of losing or winning in transition, such as unemployment, poverty, criminal, success, failure, wealth, and power. Hence, news from two internet sites "Blic" i "B92" served as a source, while their visitors ‘commentaries to the particular news served in the analysis. Specific news was used to define a particular problem or issue, and the commentaries were seen as reactions to the news. The commentaries contain readers’ attitudes, assessment of particular issues and discourses overview. These comments were chosen based on whether they refer directly to the problem of losing/winning in transition, and on their diversity regarding assessment of the problem itself. At the same time, posted texts on the mentioned sites were not unbiased, and they can also serve to identify losers and winners of transition. Defining a category of losers or winners in transition is a complex issue of various interpretations and constructions, making thus a discrepancy in attributed meanings among the members of Serbian society. Controversy and contradictions in expressed attitudes about losers and winners, as well as understanding of these categories, could be explained by various aspects and outlooks held. In brief, an existing particular social heteroglossia, assumes many different readings and attitudes regarding the categories, caused by various factors. The

  14. The dynamic behavior of the exohedral transition metal complexes ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 129; Issue 7. The dynamic behavior of the exohedral transition metal complexes of B₄₀ : η⁶- and η⁷-B₄₀Cr(CO) ₃ and Cr(CO) ₃η⁷-B₄η₀-Cr(CO) ₃. NAIWRIT KARMODAK ELUVATHINGAL D JEMMIS. REGULAR ARTICLE Volume 129 Issue 7 July 2017 pp ...

  15. Transition-Metal-Free Biomolecule-Based Flexible Asymmetric Supercapacitors.

    Science.gov (United States)

    Yang, Yun; Wang, Hua; Hao, Rui; Guo, Lin

    2016-09-01

    A transition-metal-free asymmetric supercapacitor (ASC) is successfully fabricated based on an earth-abundant biomass derived redox-active biomolecule, named lawsone. Such an ASC exhibits comparable or even higher energy densities than most of the recently reported transition-metal-based ASCs, and this green ASC generation from renewable resources is promising for addressing current issues of electronic hazard processing, high cost, and unsustainability. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Ethical commitment to women's participation in transitional justice

    OpenAIRE

    Porter, Elisabeth

    2013-01-01

    Ethical issues of justice and human rights are central to countries emerging from conflict. Yet involving women in transitional justice processes rarely is articulated in ethical terms. To make a case for an ethical commitment to improving women’s participation in these processes, the paper begins by exploring why transitional justice strategies should bother with gender. Women and men often experience conflict and injustices differently which may require different responses to redress harms ...

  17. Transitional Justice in Syria: Scenarios and Options | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... and there has been widespread destruction to property and physical infrastructure. Syria's ... The project will provide research on key transitional justice issues, including methods to ... Syrian Center for Political and Strategic Studies SCPSS.

  18. Rapid Communication: v= 2 seniority changing transitions in yrast 3 ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 89; Issue 5. Rapid Communication: Δ υ = 2 seniority changing transitions in yrast 3 − states and B ( E 3 ) systematics of Sn isotopes. BHOOMIKA MAHESHWARI SWATI GARG ASHOK KUMAR JAIN. Research Article Volume 89 Issue 5 November 2017 Article ID 75 ...

  19. Relation Between Higher Physical Activity and Public Transit Use

    Science.gov (United States)

    Vernez Moudon, Anne; Kang, Bumjoon; Hurvitz, Philip M.; Zhou, Chuan

    2014-01-01

    Objectives. We isolated physical activity attributable to transit use to examine issues of substitution between types of physical activity and potential confounding of transit-related walking with other walking. Methods. Physical activity and transit use data were collected in 2008 to 2009 from 693 Travel Assessment and Community study participants from King County, Washington, equipped with an accelerometer, a portable Global Positioning System, and a 7-day travel log. Physical activity was classified into transit- and non–transit-related walking and nonwalking time. Analyses compared physical activity by type between transit users and nonusers, between less and more frequent transit users, and between transit and nontransit days for transit users. Results. Transit users had more daily overall physical activity and more total walking than did nontransit users but did not differ on either non–transit-related walking or nonwalking physical activity. Most frequent transit users had more walking time than least frequent transit users. Higher physical activity levels for transit users were observed only on transit days, with 14.6 minutes (12.4 minutes when adjusted for demographics) of daily physical activity directly linked with transit use. Conclusions. Because transit use was directly related to higher physical activity, future research should examine whether substantive increases in transit access and use lead to more physical activity and related health improvements. PMID:24625142

  20. Rol' tranzita v jekonomike Latvii [The role of transit in the economy of Latvia

    Directory of Open Access Journals (Sweden)

    Gžibovska Nataļja

    2013-01-01

    Full Text Available Transit is an important issue in the history of world economy, including the economy of Latvia. Transit makes a significant contribution to the budget of many transit countries, one of which is the Republic of Latvia. These countries do not have significant natural resources and prefer to focus on logistics and infrastructure in order to facilitate the transit process. This article focuses on the role of transit in the economy of Latvia, whose unique geographical position makes the country an effective transport corridor (bridge in both the west-east and north-south directions. The article presents the results of an opinion poll conducted at Latvian transit enterprises regarding their future development and offers an overview of the main seaports and the Rīga international airport. The author examines the issue of Russia’s accession to the World Trade Organization and its impact on the Latvian transit, the prolongation of EU sanctions against Belarus, and the use of Latvian transport infrastructure for handling the non-military cargo traffic to/from Afghanistan. In conclusion, a forecast of possible transit development in Latvia is provided.

  1. Career Education Models. Trends and Issues Alert.

    Science.gov (United States)

    Brown, Bettina Lankard

    The evolution of the workplace has required changes in the guidance and counseling practices of career education (CE). Basic elements of CE strategies for enhancing students' career awareness, exploration, and planning are still in place, but contemporary issues such as life-work balance, involuntary career transitions, and mentoring have led to…

  2. Life Expectancy and Economic Growth : The Role of the Demographic Transition

    OpenAIRE

    Cervellati, Matteo; Sunde, Uwe

    2011-01-01

    In this paper we investigate the causal effect of life expectancy on economic growth by explicitly accounting for the role of the demographic transition. In addition to focusing on issues of empirical identification, this paper emphasizes the role of the econometric specification. We present a simple theory of the economic and demographic transition where individuals' education and fertility decisions depend on their life expectancy. The theory predicts that before the demographic transition ...

  3. Transition state theory for enzyme kinetics

    Science.gov (United States)

    Truhlar, Donald G.

    2015-01-01

    This article is an essay that discusses the concepts underlying the application of modern transition state theory to reactions in enzymes. Issues covered include the potential of mean force, the quantization of vibrations, the free energy of activation, and transmission coefficients to account for nonequilibrium effect, recrossing, and tunneling. PMID:26008760

  4. Investigation of low glass transition temperature on COTS PEM's reliability for space applications

    Science.gov (United States)

    Sandor, M.; Agarwal, S.; Peters, D.; Cooper, M. S.

    2003-01-01

    Plastic Encapsulated Microelectronics (PEM) reliability is affected by many factors. Glass transition temperature (Tg) is one such factor. In this presentation issues relating to PEM reliability and the effect of low glass transition temperature epoxy mold compounds are presented.

  5. Dose-dependent transitions in mechanisms of toxicity

    International Nuclear Information System (INIS)

    Slikker, William; Andersen, Melvin E.; Bogdanffy, Matthew S.; Bus, James S.; Cohen, Steven D.; Conolly, Rory B.; David, Raymond M.; Doerrer, Nancy G.; Dorman, David C.; Gaylor, David W.; Hattis, Dale; Rogers, John M.; Woodrow Setzer, R.; Swenberg, James A.; Wallace, Kendall

    2004-01-01

    Scientists and decision makers from all sectors agree that risk assessments should be based on the best available science. Several years ago, the Health and Environmental Sciences Institute (HESI), a global branch of the International Life Sciences Institute (ILSI), identified the need for better scientific understanding of dose-dependent transitions in mechanisms of toxicity as one avenue by which the best and latest science can be integrated into the decision making process. In July 2001, the HESI Project Committee on Dose-Dependent Transitions in Mechanisms of Toxicity established a group of academic, government, and industry scientists to engage in active technical discourse on the issue of dose-dependent transitions in mechanisms of toxicity. Over the next 18 months, case studies were examined. These case studies included acetaminophen, butadiene, ethylene glycol, formaldehyde, manganese, methylene chloride, the peroxisome proliferator-activated receptor, progesterone/hydroxyflutamide, propylene oxide, vinyl acetate, vinyl chloride, vinylidene chloride, and zinc (Slikker, W., Jr., Andersen, M.E., Bogdanffy, M.S., Bus, J.S., Cohen, S.D., Conolly, R.B., David, R.M., Doerrer, N.G., Dorman, D.C., Gaylor, D.W., Hattis, D., Rogers, J.M., Setzer, R.W., Swenberg, J.A., Wallace, K., 2004. Dose-dependent transitions in mechanisms of toxicity: case studies. Toxicol. Appl. Pharmacol. 201(3), 226-294 (this issue)). The HESI Project Committee sponsored two technical workshops in 2003. The first of these workshops took place on February 12-13, 2003, and was co-sponsored by the Agency for Toxic Substances and Disease Registry, the American Chemistry Council, the National Institute of Environmental Health Sciences, the Society of Toxicology, and the U.S. Environmental Protection Agency. Additional support was provided by Health Canada. Invited experts from government, academia, and industry provided scientific perspectives and recommendations at the workshop. The purpose of

  6. Energy transition: what is it all about?

    International Nuclear Information System (INIS)

    Grandjean, Alain

    2013-01-01

    Illustrated by many graphs, figures, maps and tables, this Power Point document presents the main issues related to energy and concerning citizens and consumers, proposes a definition of energy transition, identifies the main levers for energy transition and the main questions raised by the objectives of energy transition: energy efficiency and sobriety, trajectory to reach the energy mix, choices related to renewable energies and to energy technologies, costs and financing, governance. Other challenges are outlined and discussed: governance, energy mix, industrial policy, competitiveness and jobs, energy management, household energy consumption and poverty, climate and energy, supply safety and trade balance, health and environmental impacts, price, cost, taxing, financing and macro-economic consistency. For each of these challenges, facts are highlighted and problems to be solved are identified

  7. Protection issues on microgrid/distributed generation based systems

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Angelo R. [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET-MG), Belo Horizonte, MG (Brazil); Ribeiro, Paulo F. [Calvin College, Grand Rapids, MI (United States). Dept. of Electrical Engineering; Iung, Anderson M. [Geracao Paranapanema S.A., SP (Brazil). Duke Energy International. Market Analysis Dept.; Garcia, Paulo A.N. [Federal University of Juiz de Fora (UFJF), MG (Brazil). Dept. of Circuits

    2009-07-01

    This paper aims to discuss protection issues related to the presence of distributed generation (DG) in distribution systems. A case study is developed to show some impacts of transitions and operations with relay static settings to verify the reliability of systems in the presence of DG. (author)

  8. Transition physics and scaling overview

    International Nuclear Information System (INIS)

    Carlstrom, T.N.

    1996-01-01

    This paper presents an overview of recent experimental progress towards understanding H-mode transition physics and scaling. Terminology and techniques for studying H-mode are reviewed and discussed. The model of shear E x B flow stabilization of edge fluctuations at the L-H transition is gaining wide acceptance and is further supported by observations of edge rotation on a number of new devices. Observations of poloidal asymmetries of edge fluctuations and dephasing of density and potential fluctuations after the transition pose interesting challenges for understanding H-mode physics. Dedicated scans to determine the scaling of the power threshold have now been performed on many machines. A clear B t dependence is universally observed but dependence on the line averaged density is complicated. Other dependencies are also reported. Studies of the effect of neutrals and error fields on the power threshold are under investigation. The ITER threshold database has matured and offers guidance to the power threshold scaling issues relevant to next-step devices. (author)

  9. Transition physics and scaling overview

    International Nuclear Information System (INIS)

    Carlstrom, T.N.

    1995-12-01

    This paper presents an overview of recent experimental progress towards understanding H-mode transition physics and scaling. Terminology and techniques for studying H-mode are reviewed and discussed. The model of shear E x B flow stabilization of edge fluctuations at the L-H transition is gaining wide acceptance and is further supported by observations of edge rotation on a number of new devices. Observations of poloidal asymmetries of edge fluctuations and dephasing of density and potential fluctuations after the transition pose interesting challenges for understanding H-mode physics. Dedicated scans to determine the scaling of the power threshold have now been performed on many machines. A dear B t dependence is universally observed but dependence on the line averaged density is complicated. Other dependencies are also reported. Studies of the effect of neutrals and error fields on the power threshold are under investigation. The ITER threshold database has matured and offers guidance to the power threshold scaling issues relevant to next-step devices

  10. Energy transition: a new opportunity for the French-German cooperation

    International Nuclear Information System (INIS)

    Ruedinger, Andreas

    2015-01-01

    As France and Germany are both defining new energy policies, but in different ways (Germany has focused on a reform of the law on renewable energies, and France aims at a reduction of the nuclear share from 75 to 50 per cent by 2025), the author examines whether the French strategy is realistic and how it can be explained from a political point of view, how energy transition can be successfully implemented, and to what extent it may influence the German policy within the framework of present discussions on the EU energy-climate package and of bilateral cooperation. The author first outlines the powerful role of nuclear energy in the history of French energy policy, proposes a brief overview of the evolution of debates in France on energy policy from the beginning of the 2000's, indicates and discusses the main objectives of the present bill project on energy transition, and proposes a comparison of French and German objectives regarding energy transition by 2020, 2030 and 2050. He evokes some practical aspects (discussion about Fessenheim plant shutting down, issues of energy prices). He comments the planned implementation of a new economic model based on a green growth, discusses the issue of energy transition in the electricity sector and in the transport sector, and the relationship between energy transition and decentralisation. Perspectives are briefly discussed regarding the credibility of the French policy and the commitment of both countries in energy transition

  11. How Does This All End? Campaign Planning, Phase Transitions, and Conflict Termination in Iraq

    National Research Council Canada - National Science Library

    Goss, Thomas

    2008-01-01

    .... The political issue of how OIF ends is inherently wrapped up in the military issues of campaign planning, desired end-states, centers of gravity, and operational phase transitions in the Iraqi War...

  12. Women in Iraq: Background and Issues for U.S. Policy

    National Research Council Canada - National Science Library

    Pina, Aaron D

    2006-01-01

    The issue of women's rights in Iraq has taken on new relevance, following the U.S.-led invasion of Iraq in 2003, efforts to reconstruct Iraq, and recent elections for a Transitional National Assembly...

  13. Papers of the CAMPUT 2003 educational conference : Markets in Transition : The changing face of regulation

    International Nuclear Information System (INIS)

    2003-01-01

    The North American energy landscape is evolving: markets are in transition and regulatory roles are shifting. Regulators, government policy makers, and industry representatives exchanged information concerning the changes facing regulatory agencies, industry and energy users. The eleven sessions of the conference were entitled: (1) the future of the regulator in a continental energy market, (2) gas markets in transition, (3) electricity markets in transition (including Regional Transmission Organization/Standard Market Design issues), (4) are open access markets the answer? (5) the changing face of regulation, what's up? (6) energy policy updates in British Columbia and Atlantic Canada, (7) Ontario electricity update and deregulation one year later, (8) northern issues, (9) intervener funding, (10) affiliate transactions, regulatory and business issues, and (11) cost of capital update. The conference featured 43 presentations, of which two were indexed separately for inclusion in the database

  14. Trends in catalytic NO decomposition over transition metal surfaces

    DEFF Research Database (Denmark)

    Falsig, Hanne; Bligaard, Thomas; Rass-Hansen, Jeppe

    2007-01-01

    The formation of NOx from combustion of fossil and renewable fuels continues to be a dominant environmental issue. We take one step towards rationalizing trends in catalytic activity of transition metal catalysts for NO decomposition by combining microkinetic modelling with density functional...... theory calculations. We show specifically why the key problem in using transition metal surfaces to catalyze direct NO decomposition is their significant relative overbinding of atomic oxygen compared to atomic nitrogen....

  15. Nutritional challenges for children in societies in transition.

    Science.gov (United States)

    Cai, Wei

    2014-05-01

    This review is to explore the childhood nutrition and health in relation to socioeconomic changes in transitional countries, and to describe the good experiences and policies in these countries to combat childhood nutritional challenges. Double burden of malnutrition - the coexistence of under-nutrition and over-nutrition in the same population - is a prominent public health concern in transitional countries. With rapid industrialization, these countries are facing a growing epidemic of overweight/obesity in children and adolescents. The increasing prevalence of childhood overweight/obesity is a likely consequence of behavioral changes, and accompanied with an increasing incidence of noncommunicable chronic diseases. Although remarkable improvement of childhood nutrition was achieved, the stunting growth and micronutrient deficiency remain to be child health issues in transitional countries. The social transition caused a broad range of nutrition-associated problems. Previous successful experiences indicated that if appropriate action is undertaken, the child nutritional problems accompanied with economic transition could be controlled to some extent. However, greater efforts are needed to improve the status of childhood nutrition in transitional countries.

  16. Priorities in the School-to-Community Transition of Adolescents Who Are Deaf.

    Science.gov (United States)

    Bullis, Michael; Egelston-Dodd, Judy

    1990-01-01

    Issues relevant to the school-to-community transition of deaf adolescents were identified and subsequently prioritized by 339 deafness professionals. Issues receiving highest priority were related to joint planning efforts among schools, departments of vocational rehabilitation, and families; training of independent living skills; and development…

  17. IncA/C plasmids conferring high azithromycin resistance in vibrio cholerae.

    Science.gov (United States)

    Wang, Ruibai; Liu, Haican; Zhao, Xiuqin; Li, Jie; Wan, Kanglin

    2018-01-01

    Azithromycin (AZM) is a clinically important antibiotic against Vibrio cholerae, especially for inhibiting V. cholerae colonisation of the intestine and for the treatment of severe cholera in children and pregnant women. An IncA/C plasmid was isolated from two high minimum inhibitory concentration (MIC) AZM-resistant V. cholerae strains of the two mainly pathogenic serogroups (O1 and O139) isolated in China. In the 172 predicted open reading frames (ORFs), 16 genes were related to antibiotic resistance, of which 5 were well-defined genes associated with macrolide resistance. The five macrolide resistance genes distributed in two clusters, mphR-mrx-mph(K) and mel-mph2, flanked by insertion sequence elements and involving two kinds of resistance mechanism. Deletion of the complete region of the two clusters deceased the AZM MIC from ≥64 µg/mL to ≤0.5 µg/mL. This IncA/C plasmid shows great ability to accumulate antibiotic resistance genes. In addition to 11 resistance genes to other antibiotics, 5 macrolide resistance genes with different function were gathered repeatedly through transposition on one plasmid. This genotype could not be simply explained by antibiotic stress applied on the host from the environment or treatment. These phosphorylases and transmembrane transporters might be involved in the transport and metabolism of other non-antibiotic substances, enabling this kind of plasmid to propagate better in the host. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  18. AcEST: DK956161 [AcEST

    Lifescience Database Archive (English)

    Full Text Available otein OS=Hepatitis C virus gen... 33 0.89 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead.....OLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 10

  19. AcEST: DK957443 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Hepatitis C virus gen... 33 0.85 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 4.3 ...Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score

  20. The energy transition

    International Nuclear Information System (INIS)

    Defeuilley, Christophe

    2014-01-01

    In a first part, the author proposes an analysis of energy transition and of its consequences on the competitive environment. He recalls the main characteristics of energy transition and more particularly focuses on two aspects: the development of renewable energies and the management of demand. Thus, the author discusses the following issues: the relationship between the struggle against climate change and the low carbon economy, the development of renewable energies, the evolution and main actors of photovoltaic array and of wind turbine production, the distribution of photovoltaic and wind energy installed production among countries, and some key figures about the main renewable energy operators in Europe. He discusses how to manage consumptions, and operations performed. In a second part, the author addresses the impact of the German energy transition (Energiewende) on the business models of the main German energy operators (RWE and E.On). He recalls and comments the objective of this energy policy, presents the German electric and gas sector, comments the evolution of the electric utilities since 1998, more presently presents and discusses the activities of RWE and E.On, the evolution of their main financial indicators, and the levels of installed power with respect of energy sources

  1. Government information collections in the networked environment new issues and models

    CERN Document Server

    Cheverie, Joan F

    2013-01-01

    This insightful book explores the challenging issues related to effective access to government information.Amidst all the chaos of today's dynamic information transition period, the only constants related to government information are change and inconsistency, yet with Government Information Collections in the Networked Environment: New Issues and Models, you will defeat the challenging issues and take advantage of the opportunities that networked government information collections have to offer. This valuable book gives you a fresh opportunity to rethink collecting activities and to

  2. Hydrogen peroxide safety issues

    International Nuclear Information System (INIS)

    Conner, W.V.

    1993-01-01

    A literature survey was conducted to review the safety issues involved in handling hydrogen peroxide solutions. Most of the information found in the literature is not directly applicable to conditions at the Rocky Flats Plant, but one report describes experimental work conducted previously at Rocky Flats to determine decomposition reaction-rate constants for hydrogen peroxide solutions. Data from this report were used to calculate decomposition half-life times for hydrogen peroxide in solutions containing several decomposition catalysts. The information developed from this survey indicates that hydrogen peroxide will undergo both homogeneous and heterogeneous decomposition. The rate of decomposition is affected by temperature and the presence of catalytic agents. Decomposition of hydrogen peroxide is catalyzed by alkalies, strong acids, platinum group and transition metals, and dissolved salts of transition metals. Depending upon conditions, the consequence of a hydrogen peroxide decomposition can range from slow evolution of oxygen gas to a vapor, phase detonation of hydrogen peroxide vapors

  3. Understanding the Transition from School to University in Music and Music Technology

    Science.gov (United States)

    Winterson, Julia; Russ, Michael

    2009-01-01

    This article considers the transition from school to university in Music and Music Technology, continuing the discussion of transitional issues which began in Volume 2 of "Arts and Humanities in Higher Education". The focus of the article is a survey of undergraduates, examining areas that were key to their first experience of studying…

  4. Sustainability transitions in developing countries: Stocktaking, new contributions and a research agenda

    DEFF Research Database (Denmark)

    Hansen, Ulrich Elmer; Nygaard, Ivan; Romijn, Henny

    2018-01-01

    An increasing number of studies have analysed the scope for, and the barriers to, transitions toward sustainability in the context of developing countries building on analytical perspectives from the sustainability transitions literature. This paper introduces a special issue on sustainability...... transitions in developing countries, which takes stock of this emerging field of research and presents new empirical research that contributes to further advancement of our understanding of the conditions in which sustainability transitions are likely to take place in developing countries and what is involved...... projects. The introductory paper concludes by presenting a research agenda, which aims to provide promising avenues for future research on sustainability transitions in developing countries....

  5. Relevant training issues for introduction of digital radiology: Results of a survey

    International Nuclear Information System (INIS)

    Peer, S.; Faulkner, K.; Torbica, P.; Peer, R.; Busch, H. P.; Vetter, S.; Neofotistou, E.; Back, C.; Bosmans, H.; Vano, E.

    2005-01-01

    Council Directive 97/43/Euratom establishes the need for adequate training of radiology staff. The transition to digital radiology implies changes in various imaging aspects, which are not sufficiently covered by current institutional training programmes. This work aimed to assess how professionals, experienced in digital imaging, acquired their expertise and hence, what form institutional training should take. Within DIMOND III, a survey on training and resources was performed among radiology professionals. A lack of institutional education for digital radiology was found. In the transition to digital radiology, 30-35% train on the job and another 23-28% receive training from digital equipment vendors. A general agreement exists on the need for new quality criteria and strategies for dose management. Issues relevant for conventional/digital transition are only sparsely covered in EC training programmes. Based on these results, a set of training issues was produced, to be included in future European guidelines. (authors)

  6. Tuesdays of the future. The energy transition in debate. A season at the Hotel de Lassay, season 2013-2014, Presidency of the National Assembly

    International Nuclear Information System (INIS)

    2014-07-01

    This publication proposes synthetic transcriptions of debates regularly organised by the French National Assembly (during the 2013-2014 season) on issues related to energy and to energy transition. These debates gathered not only representatives of public authorities, but also representatives of actors of the concerned sectors, experts and even inhabitants of concerned regions of the world. These meetings addressed the following issues: transports of the 21. century (issues for rail transport, development of new clean vehicles and research in the automotive industry), the future of nuclear energy (prospective issues related to energy needs, issue of power plant ageing, evolution of electric power production and consumption, issues of safety and plant lifetime, cost of nuclear wastes), the role and commitment of territories in energy transition, the European emergency, how to finance energy transition (the decrease of public financial means, the fact that energy transition costs are in fact investments, issue of housing renovation financing, the role of banks, the lack of visibility for projects and needs), the new energies, and the Paris Climate Conference of 2015

  7. Hydrogen combustion issues and containment integrity

    International Nuclear Information System (INIS)

    Tennankore, K.N.; Koroll, G.W.; Kumar, R.K.; Lam, A.H.T.; Chan, C.K.; Wren, D.J.

    1987-01-01

    This report reviews recent results from the research program at the Whiteshell Nuclear Research Establishment aimed at resolving hydrogen combustion issues relevant to reactor containment integrity. The areas considered are hydrogen mixing behaviour, flame propagation, pressure transients caused by deflagration, flame acceleration and transition to detonation. Small-scale tests carried out with helium/CO 2 systems indicate that the presence of a recirculation path will enhance buoyancy-driven mixing of hydrogen-steam jets with air in the containment. An extensive database has been assembled for the laminar burning velocity of hydrogen-air-steam mixtures. Work is now beginning on obtaining burning velocities under turbulent conditions likely to prevail in containments. Turbulent and vented combustion data obtained in a 2.3-m-diameter spherical vessel have been analyzed. The results indicate that the pressure predictions of a one-dimensional model can be matched with the data if different effective burning velocities are used. Obstacle-induced flame acceleration and transition to detonation have been studied in a small-scale test facility to determine conditions required for transition to detonation in containments. For a repeated obstacle configuration, the obstacle blockage ratio required to cause transition (deflagation to detonation or detonation to deflagration) can be correlated well with detonation cell size. Cell sizes for mixtures of interest are being determined in our laboratory to complement available data. The transition-to-detonation process has been visualized in the above tests by Schlieren photography. The eventual objective of this work is to identify the local conditions controlling the transition process

  8. Predictors of substance use among young adults transitioning away from high school: a narrative review.

    Science.gov (United States)

    Kirst, Maritt; Mecredy, Graham; Borland, Tracey; Chaiton, Michael

    2014-11-01

    Young adulthood has been shown to be a time of increased substance use. Yet, not enough is known about which factors contribute to initiation and progression of substance use among young adults specifically during the transition year away from high school. A narrative review was undertaken to increase understanding of the predictors of changes in use of tobacco, alcohol, cannabis, other illicit drugs, and mental health problems among young adults during the transition period after high school. A review of academic literature examining predictors of the use of tobacco, alcohol and cannabis, and co-morbidities (e.g., co-occurring substance use and/or mental health issues) among young adults transitioning from high school to post-secondary education or the workforce. Twenty six studies were included in the review. The majority of the studies (19) examined substance use during the transition from high school to post-secondary settings. Seven studies examined substance use in post-secondary settings. The studies consistently found that substance use increases among young adults as they transition away from high school. During the transition away from high school, common predictors of substance use include substance use in high school, and peer influence. Common predictors of substance use in post-secondary education include previous substance use, peer influence, psychological factors and mental health issues. Conclusions/Importance: Further research on social contextual influences on substance use, mental health issues, gender differences and availability of substances during the transition period is needed to inform the development of new preventive interventions for this age group.

  9. Papers of the CAMPUT 2003 educational conference : Markets in Transition : The changing face of regulation

    International Nuclear Information System (INIS)

    2003-01-01

    The North American energy landscape is evolving: markets are in transition and regulatory roles are shifting. Regulators, government policy makers, and industry representatives exchanged information concerning the changes facing regulatory agencies, industry and energy users. The eleven sessions of the conference were entitled: (1) the future of the regulator in a continental energy market, (2) gas markets in transition, (3) electricity markets in transition (including Regional Transmission Organization/Standard Market Design issues), (4) are open access markets the answer? (5) the changing face of regulation, what's up? (6) energy policy updates in British Columbia and Atlantic Canada, (7) Ontario electricity update and deregulation one year later, (8) northern issues, (9) intervener funding, (10) affiliate transactions, regulatory and business issues, and (11) cost of capital update. The conference featured 43 presentations, of which two were indexed separately for inclusion in the database. refs., tabs., figs

  10. Youth, Politics and the Media: Legitimacy Issues in Post ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Youth, Politics and the Media: Legitimacy Issues in Post-Revolutionary Tunisia. Since Tunisia's revolution in 2011, youth have represented a fundamental challenge for the country's political stability. For public authorities in the transition period, young Tunisians personify the interweaving of three strong trends: the ...

  11. Self generation, small generation, and embedded generation issues

    International Nuclear Information System (INIS)

    2001-01-01

    The New Brunswick Market Design Committee for electric power restructuring has been directed to examine issues regarding cogeneration and small-scale, on-site generation and how they will fit within the framework of the bilateral contract market. The Committee will also have to deal with issues of generation embedded in a distribution system. The Committee has defined cogeneration as the simultaneous production of electricity and useful thermal energy. Self-generation has been defined as small-scale power generation by an end-user, while embedded generation has been defined as a generation facility that is located within a distribution utility but is not directly connected to the transmission system. The Committee has postponed its decision on whether embedded generation will be eligible to participate under the bilateral contract market for electricity. This report discusses general issues such as the physical support of generation, market support of generation, transition issues and policy issues. It also discusses generation support issues such as operating reserves, transmission tariff issues, and distribution tariffs. Market support issues such as transmission access for generation sales were also considered, along with market access for generation sales, and net metering for behind the meter generation. 7 refs., 1 tab

  12. AcEST: DK952739 [AcEST

    Lifescience Database Archive (English)

    Full Text Available BSNV Structural polyprotein OS=Blotched snakehead... 31 4.0 sp|Q7XWS7|FH12_ORYSJ Formin-like protein 12 OS=O...GGGTTGETSKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead viru

  13. AcEST: DK961245 [AcEST

    Lifescience Database Archive (English)

    Full Text Available atitis C virus gen... 33 0.85 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 4.2 sp|...uctural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 3

  14. AcEST: DK949303 [AcEST

    Lifescience Database Archive (English)

    Full Text Available POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 5.6 sp|Q7XWS7|FH12_ORYSJ Formin-like protein 12...TGETSKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE

  15. Telecommunications: Additional Federal Efforts Could Help Advance Digital Television Transition

    Science.gov (United States)

    2002-11-01

    The transition to broadcast digital television(DTV) will provide new television services and the improved picture quality of 'high definition television'. It will also allow some portions of the radiofrequency spectrum used for broadcasting to be returned for public safety and commercial uses. The Congress set December 2006 as the target date for completing the DTV transition and turning the analog broadcast signals. However, this date can be extended if fewer than 85 percent of households in a market are able to receive the digital signals. GAO (General Accounting Office) was asked to assess issues related to the DTV transition.

  16. The transit oil and gas pipeline and the role of bargaining: A non-technical discussion

    International Nuclear Information System (INIS)

    Omonbude, Ekpen J.

    2007-01-01

    Transit oil and gas pipelines are growing in relevance, and face a number of topical problems. One of such issues is the problem of potential disruption from a number of sources, notably post-construction behaviour of the transit country. Present and future pipelines face the risk of continuous conflict over legal, economic and political issues. Once the pipeline is built and in operation, the threat of disruption of the pipeline by the transit country over disputed transit terms exists. This is due to two key problems: first, a shift in bargaining powers to the transit country upon construction and operation of the pipeline and, second, changes in the value of the throughput imply price changes that can affect the behaviour of the transit country. This paper discusses the role of basic bargaining principles in cross-border oil and gas pipelines involving transit through one or more countries. It finds that the motive behind the pipeline plays a key role in the prevention of potential disruptions to the pipeline due to rent squeezing. Also, although the potential of such disruptions does exist, there are a number of factors that could serve to mute the consequences of shifts in bargaining power to the transit countries

  17. Waste to energy opportunities and challenges for developing and transition economies

    CERN Document Server

    2012-01-01

    Solid waste management is currently a major issue worldwide with numerous areas reaching critical levels. Many developing countries and countries in transition still miss basic waste management  infrastructure and awareness. It is here that many of the solid waste management problems and challenges are currently being faced. As such, waste-to-energy (WTE) consists of a proven and continuously developing spectrum and range of technologies in a number of (mostly) developed countries. However, it’s integration in developing countries and systems in transition is often faced with scepticism and a complex set of barriers which are quite unique and differ greatly from those where WTE has been validated and applied over the years. Waste-to-Energy: Opportunities and Challenges for Developing and Transition Economies will address this issue both theoretically and using concrete examples, including: ·         contributions from numerous scholars and practitioners in the field, ·         useful less...

  18. Positioning Nuclear Power in the Low-Carbon Electricity Transition

    Directory of Open Access Journals (Sweden)

    Aviel Verbruggen

    2017-01-01

    Full Text Available Addressing climate change requires de-carbonizing future energy supplies in an increasingly energy-dependent world. The IEA and the IPCC (2014 mention the following as low-carbon energy supply options: ‘renewable energy, nuclear power and fossil fuels with carbon capture and storage’. Positioning nuclear power in the decarbonization transition is a problematic issue and is overridden by ill-conceived axioms. Before probing these axioms, we provide an overview of five major, postwar energy-related legacies and some insight into who is engaged in nuclear activities. We check whether low-carbon nuclear power passes the full sustainability test and whether it is compatible with the unfettered deployment of variable renewable power sourced from the sun and from wind and water currents, which delivers two negative answers. We show that the best approach of the sustainable energy transition was Germany’s 2011 decision to phase out nuclear power for a fast development and full deployment of renewable power. This is the best approach for the sustainable energy transition. We offer five practical suggestions to strengthen and accelerate carbon- and nuclear-free transitions. They are related to institutional issues like the role of cost-benefit analysis and the mission of the International Atomic Energy Agency, to the costs of nuclear risks and catastrophes, and to the historical record of nuclear technology and business.

  19. Career Development for Transitioning Veterans. Monograph Series

    Science.gov (United States)

    McCormick, Carmen Stein; Osborn, Debra S.; Hayden, Seth C. W.; Van Hoose, Dan

    2013-01-01

    The purpose of this book is to increase career practitioners' awareness of the transition issues and resources specific to veterans and to provide several examples of how a practitioner might walk a veteran through the career planning process. Case studies based on interviews with real veterans by the authors and military consultants (Thomas…

  20. Characteristics of the Mott transition and electronic states of high-temperature cuprate superconductors from the perspective of the Hubbard model

    Science.gov (United States)

    Kohno, Masanori

    2018-04-01

    A fundamental issue of the Mott transition is how electrons behaving as single particles carrying spin and charge in a metal change into those exhibiting separated spin and charge excitations (low-energy spin excitation and high-energy charge excitation) in a Mott insulator. This issue has attracted considerable attention particularly in relation to high-temperature cuprate superconductors, which exhibit electronic states near the Mott transition that are difficult to explain in conventional pictures. Here, from a new viewpoint of the Mott transition based on analyses of the Hubbard model, we review anomalous features observed in high-temperature cuprate superconductors near the Mott transition.

  1. Transition radiation and transition scattering

    International Nuclear Information System (INIS)

    Ginzburg, V.L.

    1982-01-01

    Transition radiation is a process of a rather general character. It occurs when some source, which does not have a proper frequency (for example, a charge) moves at a constant velocity in an inhomogeneous and (or) nonstationary medium or near such a medium. The simplest type of transition radiation takes place when a charge crosses a boundary between two media (the role of one of the media may be played by vacuum). In the case of periodic variation of the medium, transition radiation possesses some specific features (resonance transition radiation or transition scattering). Transition scattering occurs, in particular, when a permittivity wave falls onto an nonmoving (fixed) charge. Transition scattering is closely connected with transition bremsstrahlung radiation. All these transition processes are essential for plasma physics. Transition radiation and transition scattering have analogues outside the framework of electrodynamics (like in the case of Vavilov-Cherenkov radiation). In the present report the corresponding range of phenomena is elucidated, as far as possible, in a generally physical aspect. (Auth.)

  2. High Intensity Beam Issues in the CERN Proton Synchrotron

    CERN Document Server

    Aumon, Sandra; Rivkin, Leonid

    This PhD work is about limitations of high intensity proton beams observed in the CERN Proton Synchrotron (PS) and, in particular, about issues at injection and transition energies. With its 53 years, the CERN PS would have to operate beyond the limit of its performance to match the future requirements. Beam instabilities driven by transverse impedance and aperture restrictions are important issues for the operation and for the High-Luminosity LHC upgrade which foresees an intensity increase delivered by the injectors. The main subject of the thesis concerns the study of a fast transverse instability occurring at transition energy. The proton beams crossing this energy range are particularly sensitive to wake forces because of the slow synchrotron motion. This instability can cause a strong vertical emittance blow-up and severe losses in less than a synchrotron period. Experimental observations show that the particles at the peak density of the beam longitudinal distribution oscillate in the vertical plane du...

  3. "SOE Reform and Privatization in China---A note on several theoretical and empirical issues"

    OpenAIRE

    Katsuji Nakagane

    2000-01-01

    State owned enterprise (SOE) reform is one of the biggest issues for every transition economy. Even the Chinese economy, which is widely known as a successful case for "gradualist" economic transition, has been faced with poor management and low efficiency of many SOEs. As in the case for well-known arguments on transition strategies, i.e. gradualism vs. shock therapy, there has been a heated debate centering on the effectiveness of privatization of state enterprises. Conventional wisdom is t...

  4. Transitioning the Allergy/Immunology Patient from Childhood to Adulthood.

    Science.gov (United States)

    Hoyte, Flavia C L

    2017-06-01

    Allergic disorders and immunodeficiencies are generally chronic and even lifelong conditions, often changing over time, making the cautious transition of care from childhood to adulthood particularly important. Many, but not all, patients can continue to receive their care from the same physician as they transition through adolescence and emerging adulthood, made possible because allergy/immunology training programs require cross-training in the care of both pediatric and adult patients. Although keeping the same physician makes the transition easier for many allergy/immunology patients, even these patients face psychosocial issues unique to adolescents and emerging adults, including increased autonomy, risk-taking behavior, and medical self-management. Successful transition for patients with chronic allergic and immunologic conditions involves an understanding of the natural history of these conditions by patients and physicians alike, a gradual increase in self-management depending on individual readiness, and careful communication between pediatric and adult specialists as care is transitioned. [Pediatr Ann. 2017;46(6):e229-e234.]. Copyright 2017, SLACK Incorporated.

  5. Transition care for children with special health care needs.

    Science.gov (United States)

    Davis, Alaina M; Brown, Rebekah F; Taylor, Julie Lounds; Epstein, Richard A; McPheeters, Melissa L

    2014-11-01

    Approximately 750,000 children in the United States with special health care needs will transition from pediatric to adult care annually. Fewer than half receive adequate transition care. We had conversations with key informants representing clinicians who provide transition care, pediatric and adult providers of services for individuals with special health care needs, policy experts, and researchers; searched online sources for information about currently available programs and resources; and conducted a literature search to identify research on the effectiveness of transition programs. We identified 25 studies evaluating transition care programs. Most (n = 8) were conducted in populations with diabetes, with a smaller literature (n = 5) on transplant patients. We identified an additional 12 studies on a range of conditions, with no more than 2 studies on the same condition. Common components of care included use of a transition coordinator, a special clinic for young adults in transition, and provision of educational materials. The issue of how to provide transition care for children with special health care needs warrants further attention. Research needs are wide ranging, including both substantive and methodologic concerns. Although there is widespread agreement on the need for adequate transition programs, there is no accepted way to measure transition success. It will be essential to establish consistent goals to build an adequate body of literature to affect practice. Copyright © 2014 by the American Academy of Pediatrics.

  6. A Comparison of Materials Issues for Cermet and Graphite-Based NTP Fuels

    Science.gov (United States)

    Stewart, Mark E.; Schnitzler, Bruce G.

    2013-01-01

    This paper compares material issues for cermet and graphite fuel elements. In particular, two issues in NTP fuel element performance are considered here: ductile to brittle transition in relation to crack propagation, and orificing individual coolant channels in fuel elements. Their relevance to fuel element performance is supported by considering material properties, experimental data, and results from multidisciplinary fluid/thermal/structural simulations. Ductile to brittle transition results in a fuel element region prone to brittle fracture under stress, while outside this region, stresses lead to deformation and resilience under stress. Poor coolant distribution between fuel element channels can increase stresses in certain channels. NERVA fuel element experimental results are consistent with this interpretation. An understanding of these mechanisms will help interpret fuel element testing results.

  7. Hadron wave functions and the issue of nucleon deformation

    International Nuclear Information System (INIS)

    Alexandrou, C.; Forcrand, Ph. de; Tsapalis, A.

    2003-01-01

    Using gauge invariant hadronic two- and three- density correlators we extract information on the spatial distributions of quarks in hadrons, and on hadron shape and multipole moments within quenched lattice QCD. Combined with the calculation of N to Δ transition amplitudes the issue of nucleon deformation can be addressed

  8. Media Education across Four Asian Societies: Issues and Themes

    Science.gov (United States)

    Cheung, Chi-Kim

    2009-01-01

    This paper undertakes a comparative review of the development and implementation of media education in four Asian societies. The comparison focuses on the following issues: the general pedagogical transition from inoculation to empowerment; the roles of government policy and educational reform in facilitating the development of media education;…

  9. AcEST: DK962818 [AcEST

    Lifescience Database Archive (English)

    Full Text Available _BSNV Structural polyprotein OS=Blotched snakehead... 31 5.2 sp|Q7XWS7|FH12_ORYSJ Formin-like protein 12 OS=...SKSPPDEPDDSEAGSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 S

  10. Disorders of lipid metabolism in 3 patients with diabetes mellitus type 2

    NARCIS (Netherlands)

    Wolffenbuttel, B.H.R.; Huijberts, M.S.P.

    2001-01-01

    Disorders of lipid metabolism in 3 patients with diabetes mellitus type 2] [Article in Dutch] Wolffenbuttel BH, Huijberts MS. Academisch Ziekenhuis, afd. Endocrinologie, Postbus 5800, 6202 AZ Maastrict. bwo@sint.azm.nl Three patients with diabetes mellitus (type 2) and cardiovascular disease had

  11. Simplified Transit Procedure in Railway Transport

    Directory of Open Access Journals (Sweden)

    Željko Kokorović

    2008-11-01

    Full Text Available The current transit procedure in railway transport that iscarried out on the basis of the Customs Act [ 11 of the Republicof Croatia is applied only up to the border, i. e. the issued documentsand guarantees are valid only up to the border, and byjoining the Convention on Common transit procedure, i. e. integrationof the Republic of Croatia in the European Union, theRepublic of Croatia will also have to implement the regulationsand rules of Simplified transit procedure valid in each of thethirty member states. In international railway traffic, the transportof goods is regulated by the Convention concerning InternationalCarriage by Rail- COT IF [2 1 and usage of the CIMwaybill (Contract for International Carriage of Goods by Rail.If the goods are transported in Simplified transit procedure, theformalities regarding the transport of goods performed by railcarriers using the international waybill CIM will be significantlysimplified and accelerated. In principle there are no delays dueto customs on the borders when crossing the EU borders andborders of the Convention member states, contributing greatlyto the acceleration of the transport of goods, reduction of waitingcosts and paperwork, as well as influence on the schedulereliability.

  12. Religious changes in post-communism: The issue of orthodoxy in the transitional societies of Serbia and Montenegro and Russia

    Directory of Open Access Journals (Sweden)

    Blagojević Mirko 1

    2003-01-01

    Full Text Available Considering this issue to be particularly significant as a research challenge for the sociologies of religion in the so-called post-socialist countries, the subject of this research has been to determine the character, status and direction of religious changes in predominantly orthodox territories of Yugoslavia (Serbia and Montenegro and Russia that became evident in the last decade of the twentieth century marked by turbulent socio-political changes in those countries. With the subject of the research being defined in that way, the main goal of the research has been to identify and examine basic tendencies in religious changes. Relying on the huge empirical material on the changes in question, an attempt has been made to precisely detect the scope of these changes in the various areas of religious, spiritual and social lives of people in the period of the so-called post-socialist transformation (transition. Therefore, the goal of the research has not been just to determine the scope and direction of changes of religiousness with people, but also to try to set the above mentioned religious changes into the proper social context, which is the starting point in their theoretical explanation.

  13. Electronic traffic signs: Reflecting upon its transition

    Energy Technology Data Exchange (ETDEWEB)

    Arbaiza Martin, A.E.; Alba, A.L.; Hernando Mazon, A.; Blanch Mico, M.T.

    2016-07-01

    In our days we face a fundamental issue concerning road signs. We may display contents in vertical and horizontal format (static signs, variable message signs, road markings), either on a post, a gantry or a dashboard. And we foresee a coming age where the excellent matrix resolution of painted signs will be truly approached by the resolution of full matrix displays. But we also risk a babel context threatening the universal approach encouraged by international catalogues as the 1968 Convention (ECE/TRANS/196, 2007). And the fundamental risk comes from our decisions regarding how the transition from the contents and formats displayed on static message signs to the ones displayed on electronic signs (in gantries or dashboards) should be. Our work explores this issue specifically, considering the transition from Advance Direction Signs (static message signs, class G, 1 in the 1968 Convention) to what could be termed Advance Location Signs (signs concerning the location of variable events with regards to certain landmarks) developed as an adaptation of the G, 1 class to electronic traffic signs.(Author)

  14. Superconductor-insulator transitions in 2D: the experimental situation

    International Nuclear Information System (INIS)

    Markovic, N.; Christiansen, C.; Mack, A.; Goldman, A.M.

    2000-01-01

    Superconductor-insulator (SI) transitions in ultrathin films have attracted significant attention over the last decade because of the possibility that they are quantum phase transitions. Magnetic field, film thickness, or carrier concentration can be used as control parameters. The bosonic pictures of these transitions proposed some years ago are only in qualitative agreement with experiment. In particular, the critical resistance appears not to be universal, and there are variations in the values of critical exponents. It has been concluded that in real films fermionic degrees of freedom must be taken into account. There are also indications that the phase diagram may include a significant metallic phase separating the superconducting and insulating phases, and that the transition may have a significant percolative aspect. The experimental situation will be broadly reviewed with attention paid to issues relating to materials and measurements. (orig.)

  15. Polymorphic phase transitions: Macroscopic theory and molecular simulation.

    Science.gov (United States)

    Anwar, Jamshed; Zahn, Dirk

    2017-08-01

    Transformations in the solid state are of considerable interest, both for fundamental reasons and because they underpin important technological applications. The interest spans a wide spectrum of disciplines and application domains. For pharmaceuticals, a common issue is unexpected polymorphic transformation of the drug or excipient during processing or on storage, which can result in product failure. A more ambitious goal is that of exploiting the advantages of metastable polymorphs (e.g. higher solubility and dissolution rate) while ensuring their stability with respect to solid state transformation. To address these issues and to advance technology, there is an urgent need for significant insights that can only come from a detailed molecular level understanding of the involved processes. Whilst experimental approaches at best yield time- and space-averaged structural information, molecular simulation offers unprecedented, time-resolved molecular-level resolution of the processes taking place. This review aims to provide a comprehensive and critical account of state-of-the-art methods for modelling polymorph stability and transitions between solid phases. This is flanked by revisiting the associated macroscopic theoretical framework for phase transitions, including their classification, proposed molecular mechanisms, and kinetics. The simulation methods are presented in tutorial form, focusing on their application to phase transition phenomena. We describe molecular simulation studies for crystal structure prediction and polymorph screening, phase coexistence and phase diagrams, simulations of crystal-crystal transitions of various types (displacive/martensitic, reconstructive and diffusive), effects of defects, and phase stability and transitions at the nanoscale. Our selection of literature is intended to illustrate significant insights, concepts and understanding, as well as the current scope of using molecular simulations for understanding polymorphic

  16. Prader–Willi syndrome: clinical problems in transition from pediatric to adult care

    Directory of Open Access Journals (Sweden)

    Crinò A

    2016-07-01

    Full Text Available Antonino Crinò,1 Danilo Fintini,1 Sarah Bocchini,1 Chiara Carducci,1 Graziano Grugni,2 1Autoimmune Endocrine Diseases Unit, Bambino Gesù Children’s Hospital, Research Institute, Palidoro, Rome, 2Division of Auxology, Italian Auxological Institute, Research Institute, Piancavallo, Verbania, Italy Abstract: Prader–Willi syndrome (PWS represents the most common form of genetic obesity. Thanks to the advances in medical care and technology, many persons with PWS live longer and survive to adulthood. Currently, because of the many physical and behavioral manifestations, transitional health care is not easy for these patients and is considered a very important issue. Moreover, very few studies have examined these transitional problems in young adults with PWS. In recent years, there has been great interest in improving transition planning and support for young people with PWS reaching adulthood. In this article, we underline the main clinical problems in transition and give some advice to make this period less difficult and easier for adolescents with PWS. Special attention should be paid to obesity, diabetes mellitus, hypertension, osteoporosis, and sleep apnea during the period of transition. In PWS, for an effective transition from childhood to adulthood, a multidisciplinary team is needed, and should maintain the same approach to food, environment, and psychiatric issues. For comprehensive care, it is necessary to involve adult endocrinologists and other medical specialists in conjunction with the pediatric team. Parental involvement is, however, a great help for supervising adolescents with PWS during this particular period. Keywords: Prader–Willi, transition period, intellectual disabilities

  17. The role of hydrocarbons in energy transition

    International Nuclear Information System (INIS)

    2015-11-01

    This publication presents some reflections and statements as well as data regarding the role of hydrocarbons in energy production and consumption, in order to better highlight the role hydrocarbons may have in energy transition. It outlines the still very important share of oil in primary and final energy, and more particularly in transports, and that, despite the development of other energies, an energy transition is always very slow. It discusses the perspectives for hydrocarbon reserves and production of oil and natural gas. It outlines that oil remains the most important energy for mobility, the benefits of conventional fuels, and that distribution infrastructures must be preserved and developed. It discusses the evolution of the economic situation of the refining activity (more particularly its margin). It outlines the high contribution of oil industry to economic activity and employment in France, discusses the French energy taxing policy and environmental taxing policy, discusses the issue of security of energy supply (with its different components: exploration-production, refining, logistics and depots, distribution and station network). It discusses the possible role shale hydrocarbons may have in the future. For each issue, the position and opinion of the UFIP (the French Union of oil industries) is stated. The second part of the document proposes a Power Point presentation with several figures and data on these issues

  18. Investigation of low glass transition temperature on COTS PEMs reliability

    Science.gov (United States)

    Sandor, M.; Agarwal, S.

    2002-01-01

    Many factors influence PEM component reliability.One of the factors that can affect PEM performance and reliability is the glass transition temperature (Tg) and the coefficient of thermal expansion (CTE) of the encapsulant or underfill. JPL/NASA is investigating how the Tg and CTE for PEMs affect device reliability under different temperature and aging conditions. Other issues with Tg are also being investigated. Some preliminary data will be presented on glass transition temperature test results conducted at JPL.

  19. Development of test practice requirements for a standard method on fracture toughness testing in the transition range

    International Nuclear Information System (INIS)

    McCabe, D.E.; Zerbst, U.; Heerens, J.

    1993-01-01

    This report covers the resolution of several issues that are relevant to the ductile to brittle transition range of structural steels. One of this issues was to compare a statistical-based weakest-link method to constraint data adjustment methods for modeling the specimen size effects on fracture toughness. Another was to explore the concept of a universal transition temperature curve shape (Master Curve). Data from a Materials Properties Council round robin activity were used to test the proposals empirically. The findings of this study are inclosed in an activity for the development of a draft standard test procedure ''Test Practice for Fracture Toughness in the Transition Range''. (orig.) [de

  20. Energy transition in France. A view of challenges and controversies. Proceedings of the first day, Friday 21 June 2013: Energy transition, society projects, and present tensions

    International Nuclear Information System (INIS)

    Billy, Isabelle; Ha-Duong, Minh; Finon, Dominique; Laugier, S.; Dollet, A.; Lecocq, F.; Bibas, R.; Hourcade, J.C.; Moisan, F.; Criqui, P.; Moncomble, J.E.; Salomon, T.; Bompart, J.P.; Crassous, Renaud; Geoffron, Patrice; Egenhofer, C.; Zachmann, G.; Baron, R.; Bussieras, M.; Salaun, Fabienne; Benassy-Quere, A.; Quirion, P.; Giraud, P.N.; Crifo, P.; Tutenuit, C.; Mestre, A.; Ghersi, Frederic; Bureau, D.; Giraud, G.; Lipietz, A.; Guivarch, Celine; Grubb, M.J.; Egenhofer, Christian; Watkinson, Paul; Lecocq, Franck

    2013-01-01

    The contributions of this meeting issues related to energy transition are proposed for different themes: decisions and objectives (a prospective study for energy transitions in France, comments on ADEME's transition scenarios and their micro-economic impacts, structuring scenarios, assessment criteria and blind points in energy transition, comments of French scenarios with respect to the prospective methodology of energy transition of the World Energy Council), market mechanisms in Europe (inner contradictions of European policies about market regime, low carbon policies and renewable energy policies, tension between the European regime of integrated electricity markets and the originality of national policies within the EU, designing energy transition in a member-state with or without taking European integration into account), energy, employment and growth modes (the impact of energy transition in France on jobs studied by means of an input-output analysis, energy transition as a re-balancing factor between nomadic and sedentary jobs, the impact of a green growth on jobs), financing transition and leaving stagnation, and the world transition towards a low carbon society (planetary economics, concepts and tools of transition and implications for European policy). The content of a round table and a synthesis are given for each of these themes

  1. Fluorinated epoxy resins with high glass transition temperatures

    Science.gov (United States)

    Griffith, James R.

    1991-01-01

    Easily processed liquid resins of low dielectric constants and high glass transition temperatures are useful for the manufacture of certain composite electronic boards. That combination of properties is difficult to acquire when dielectric constants are below 2.5, glass transition temperatures are above 200 C and processability is of conventional practicality. A recently issued patent (US 4,981,941 of 1 Jan. 1991) teaches practical materials and is the culmination of 23 years of research and effort and 15 patents owned by the Navy in the field of fluorinated resins of several classes. In addition to high fluorine content, practical utility was emphasized.

  2. The bill project on energy transition: what will happen to renewable energies

    International Nuclear Information System (INIS)

    Darson, Alice

    2015-01-01

    The author comments and discusses the content of the French bill project on energy transition, and the controversies on this bill project within the French Parliament. She addresses the objectives of the bill project (share of renewable energies, case of overseas territories), the issue of building construction and renovation, the issue of transports (fleet size, electric vehicles, use of renewable energy), the development of renewable energies (notably for overseas territories, issue of mandatory purchase, issue of connection), the simplification and clarification of procedures, and the possibility for citizen, enterprises, territories and State to act together

  3. AcEST: DK960462 [AcEST

    Lifescience Database Archive (English)

    Full Text Available nome polyprotein OS=Hepatitis C virus gen... 33 0.91 sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snake...|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length = 1069 Score = 31.2 bits (69)

  4. Lessons from previous 'coal Transitions'. High-level summary for decision-makers, Part of 'Coal Transitions: Research and Dialogue on the Future of Coal' Project

    International Nuclear Information System (INIS)

    Caldecott, Ben; Sartor, Oliver; Spencer, Thomas

    2017-01-01

    The need for a so-called 'just transition' is acknowledged, away from carbon intensive activities, such as coal production and use. But what might a just transition look like in practice? What specific risks need to be managed and what are the best approaches to managing them? There is an urgent need to develop a deeper understanding of these issues. It is to this need that this report tries to respond. It provides a summary of lessons from six historical case studies of regional coal mining transitions that have occurred or are ongoing in Europe and the United States in recent decades. These case studies and this report were developed as part of a broader project led by IDDRI and Climate Strategies, entitled 'Coal Transitions: Research and Dialogue on the Future of Coal'. This project seeks to utilise these historical lessons to facilitate the development of feasible coal transition scenarios in large coal producing countries today'

  5. Concluding Comments about Student Transition to Higher Education

    Science.gov (United States)

    Cole, James S.

    2017-01-01

    This special issue of Transition to Higher Education contained studies from nine countries across the globe. The following provides a brief review of all nine studies, identifying common themes. These common themes include the importance of student expectations regarding their first-year experiences, as well as the importance of student academic…

  6. Mass fractionation processes of transition metal isotopes

    Science.gov (United States)

    Zhu, X. K.; Guo, Y.; Williams, R. J. P.; O'Nions, R. K.; Matthews, A.; Belshaw, N. S.; Canters, G. W.; de Waal, E. C.; Weser, U.; Burgess, B. K.; Salvato, B.

    2002-06-01

    Recent advances in mass spectrometry make it possible to utilise isotope variations of transition metals to address some important issues in solar system and biological sciences. Realisation of the potential offered by these new isotope systems however requires an adequate understanding of the factors controlling their isotope fractionation. Here we show the results of a broadly based study on copper and iron isotope fractionation during various inorganic and biological processes. These results demonstrate that: (1) naturally occurring inorganic processes can fractionate Fe isotope to a detectable level even at temperature ˜1000°C, which challenges the previous view that Fe isotope variations in natural system are unique biosignatures; (2) multiple-step equilibrium processes at low temperatures may cause large mass fractionation of transition metal isotopes even when the fractionation per single step is small; (3) oxidation-reduction is an importation controlling factor of isotope fractionation of transition metal elements with multiple valences, which opens a wide range of applications of these new isotope systems, ranging from metal-silicate fractionation in the solar system to uptake pathways of these elements in biological systems; (4) organisms incorporate lighter isotopes of transition metals preferentially, and transition metal isotope fractionation occurs stepwise along their pathways within biological systems during their uptake.

  7. Resource Allocation for Sustainable Urban Transit from a Transport Diversity Perspective

    Directory of Open Access Journals (Sweden)

    Cheng-Min Feng

    2009-11-01

    Full Text Available Different transport stakeholders have different needs for transport infrastructure and services. Meeting the needs of all stakeholders implies a trade-off of benefits and costs between supply and demand and creates transport diversity issues. However, the literature has largely ignored these issues. Transport diversity can assess the level to which important needs are satisfied equitably, and monitor whether transportation systems are moving towards sustainability by confirming the targets and basic level of quality of life. Based on the concept of transport diversity, this study utilizes fuzzy multi-objective programming to solve non-linear multi-objective problems involving urban public transit systems to determine the impact of resource allocation on needs satisfaction in relation to stakeholder behaviors. The proposed approach avoids problems of inefficient and inequitable resource allocation. A real-life case is presented to demonstrate the feasibility of applying the proposed methodology. Furthermore, empirical outcomes show that recent investments allocated to public transit systems considered equitable stakeholder satisfaction for both mass rapid transit (MRT and bus, and also promoted transport diversity in the Taipei metropolitan area.

  8. Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition

    Directory of Open Access Journals (Sweden)

    Satoshi Nori

    2015-03-01

    Full Text Available Previously, we described the safety and therapeutic potential of neurospheres (NSs derived from a human induced pluripotent stem cell (iPSC clone, 201B7, in a spinal cord injury (SCI mouse model. However, several safety issues concerning iPSC-based cell therapy remain unresolved. Here, we investigated another iPSC clone, 253G1, that we established by transducing OCT4, SOX2, and KLF4 into adult human dermal fibroblasts collected from the same donor who provided the 201B7 clone. The grafted 253G1-NSs survived, differentiated into three neural lineages, and promoted functional recovery accompanied by stimulated synapse formation 47 days after transplantation. However, long-term observation (for up to 103 days revealed deteriorated motor function accompanied by tumor formation. The tumors consisted of Nestin+ undifferentiated neural cells and exhibited activation of the OCT4 transgene. Transcriptome analysis revealed that a heightened mesenchymal transition may have contributed to the progression of tumors derived from grafted cells.

  9. Stable isotopes of transition and post-transition metals as tracers in environmental studies

    Science.gov (United States)

    Bullen, Tomas D.; Baskaran, Mark

    2011-01-01

    The transition and post-transition metals, which include the elements in Groups 3–12 of the Periodic Table, have a broad range of geological and biological roles as well as industrial applications and thus are widespread in the environment. Interdisciplinary research over the past decade has resulted in a broad understanding of the isotope systematics of this important group of elements and revealed largely unexpected variability in isotope composition for natural materials. Significant kinetic and equilibrium isotope fractionation has been observed for redox sensitive metals such as iron, chromium, copper, molybdenum and mercury, and for metals that are not redox sensitive in nature such as cadmium and zinc. In the environmental sciences, the isotopes are increasingly being used to understand important issues such as tracing of metal contaminant sources and fates, unraveling metal redox cycles, deciphering metal nutrient pathways and cycles, and developing isotope biosignatures that can indicate the role of biological activity in ancient and modern planetary systems.

  10. Inorganic Surface Coating with Fast Wetting-Dewetting Transitions for Liquid Manipulations.

    Science.gov (United States)

    Yang, Yajie; Zhang, Liaoliao; Wang, Jue; Wang, Xinwei; Duan, Libing; Wang, Nan; Xiao, Fajun; Xie, Yanbo; Zhao, Jianlin

    2018-06-06

    Liquid manipulation is a fundamental issue for microfluidics and miniaturized sensors. Fast wetting-state transitions by optical methods have proven being efficient for liquid manipulations by organic surface coatings, however rarely been achieved by using inorganic coatings. Here, we report a fast optical-induced wetting-state transition surface achieved by inorganic coating, enabling tens of second transitions for a wetting-dewetting cycle, shortened from an hour, as typically reported. Here, we demonstrate a gravity-driven microfluidic reactor and switch it to a mixer after a second-step exposure in a minimum of within 80 s of UV exposure. The fast wetting-dewetting transition surfaces enable the fast switchable or erasable smart surfaces for water collection, miniature chemical reaction, or sensing systems by using inorganic surface coatings.

  11. The transition from pediatric to adult care for youth with epilepsy: Basic biological, sociological, and psychological issues.

    Science.gov (United States)

    Camfield, Peter; Camfield, Carol; Busiah, Kanetee; Cohen, David; Pack, Alison; Nabbout, Rima

    2017-04-01

    Transition from pediatric to adult health care for adolescents with epilepsy is challenging for the patient, family, and health care workers. This paper is the first of three that summarize the main findings from the 2nd Symposium on Transition in Epilepsies, held in Paris from June 14-25, 2016. In this paper we describe five basic themes that have an important effect on transition. First, there are important brain changes in adolescence that leave an imbalance between risk taking and pleasure seeking behaviors and frontal executive function compared with adults. Second, puberty is a major change during the transition age. The three most important but separate neuroendocrine axes involved in puberty are gonadarche (activation of the gonads), adrenarche (activation of adrenal androgen production), and activation of the growth hormone-insulin like growth factor. Third, sexual debut occurs during the transition years, and at an earlier age in adolescents with epilepsy than controls. Adult sexual performance is often unsatisfactory. Although AED-induced alterations in sexual hormones and temporal lobe epilepsy may play a role in hyposexuality, depression, anxiety, and other social factors appear most important. Fourth, psychological development is very important with an evolution from an early stage (ages 10-13years) with concrete thinking, to a middle stage (ages 14-17) with analytic and more abstract introspective thinking, and then to a late stage (ages 18-21) with at least the beginnings of adult reasoning. Epilepsy may derail this relatively orderly progression. Adolescents with autistic spectrum disorder may present with severe behavior problems that are sometimes related to undiagnosed epilepsy. Fifth, bone health in adolescence is critical to establish adequate mineralization for all of adult life. While AED interference with Vitamin D metabolism is important, there is evidence that the effects of AEDs on bone are more complex and involve changes in remodeling

  12. Quantifying Urban Fragmentation under Economic Transition in Shanghai City, China

    Directory of Open Access Journals (Sweden)

    Heyuan You

    2015-12-01

    Full Text Available Urban fragmentation affects sustainability through multiple impacts on economic, social, and environmental cost. Characterizing the dynamics of urban fragmentation in relation to economic transition should provide implications for sustainability. However, rather few efforts have been made in this issue. Using the case of Shanghai (China, this paper quantifies urban fragmentation in relation to economic transition. In particular, urban fragmentation is quantified by a time-series of remotely sensed images and a set of landscape metrics; and economic transition is described by a set of indicators from three aspects (globalization, decentralization, and marketization. Results show that urban fragmentation presents an increasing linear trend. Multivariate regression identifies positive linear correlation between urban fragmentation and economic transition. More specifically, the relative influence is different for the three components of economic transition. The relative influence of decentralization is stronger than that of globalization and marketization. The joint influences of decentralization and globalization are the strongest for urban fragmentation. The demonstrated methodology can be applicable to other places after making suitable adjustment of the economic transition indicators and fragmentation metrics.

  13. Size matters: the ethical, legal, and social issues surrounding large-scale genetic biobank initiatives

    Directory of Open Access Journals (Sweden)

    Klaus Lindgaard Hoeyer

    2012-04-01

    Full Text Available During the past ten years the complex ethical, legal and social issues (ELSI typically surrounding large-scale genetic biobank research initiatives have been intensely debated in academic circles. In many ways genetic epidemiology has undergone a set of changes resembling what in physics has been called a transition into Big Science. This article outlines consequences of this transition and suggests that the change in scale implies challenges to the roles of scientists and public alike. An overview of key issues is presented, and it is argued that biobanks represent not just scientific endeavors with purely epistemic objectives, but also political projects with social implications. As such, they demand clever maneuvering among social interests to succeed.

  14. AcEST: DK963597 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ral polyprotein OS=Blotched snakehead... 31 5.0 sp|Q7XWS7|FH12_ORYSJ Formin-like protein 12 OS=Oryza sativa ...GSVSSMPPLEG 2401 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=1 SV=1 Length =

  15. Natural gas transits and market power. The case of Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Weiser, Florian; Schulte, Simon

    2017-08-15

    Turkey is a key country in order to realize the Southern Gas Corridor (SGC) due to its geographical location. However, as the main transit country within the SGC, Turkey could potentially exert market power with gas transits. Whether Turkey exerts market power or not, is crucial for an economic assessment of the SGC. Hence, the article investigates this issue quantitatively using a global partial equilibrium gas market model. An oligopolistic and a competitive supply structure in Europe in 2030 are considered in the model. If the European gas market in 2030 is characterized by an oligopolistic supply, Turkey is able to exert market power resulting in higher prices compared to competitive transits, in particular in South Eastern Europe. In a competitive market structure, however, the importance of the SGC and thus the potential of Turkish transit market power is limited.

  16. Natural gas transits and market power. The case of Turkey

    International Nuclear Information System (INIS)

    Weiser, Florian; Schulte, Simon

    2017-01-01

    Turkey is a key country in order to realize the Southern Gas Corridor (SGC) due to its geographical location. However, as the main transit country within the SGC, Turkey could potentially exert market power with gas transits. Whether Turkey exerts market power or not, is crucial for an economic assessment of the SGC. Hence, the article investigates this issue quantitatively using a global partial equilibrium gas market model. An oligopolistic and a competitive supply structure in Europe in 2030 are considered in the model. If the European gas market in 2030 is characterized by an oligopolistic supply, Turkey is able to exert market power resulting in higher prices compared to competitive transits, in particular in South Eastern Europe. In a competitive market structure, however, the importance of the SGC and thus the potential of Turkish transit market power is limited.

  17. Stabilization Mechanism of Roxithromycin Tablets under Gastric pH Conditions.

    Science.gov (United States)

    Inukai, Koki; Noguchi, Shuji; Kimura, Shin-Ichiro; Itai, Shigeru; Iwao, Yasunori

    2018-05-31

    Macrolide antibiotics are widely used at clinical sites. Clarithromycin (CAM), a 14-membered macrolide antibiotic, was reported to gelate under acidic conditions. Gelation allows oral administration of acid-sensitive CAM without enteric coating by hindering the penetration of gastric fluid into CAM tablets. However, it is unknown whether this phenomenon occurs in other macrolide antibiotics. In this study, we examined the gelation ability of three widely used macrolide antibiotics, roxithromycin (RXM), erythromycin A (EM), and azithromycin (AZM). The results indicated that not only CAM but also RXM gelated under acidic conditions. EM and AZM did not gelate under the same conditions. Gelation of RXM delayed the disintegration of the tablet and release of RXM from the tablet. Disintegration and release were also delayed in commercial RXM tablets containing disintegrants. This study showed that two of the four macrolides gelated, which affects tablet disintegration and dissolution and suggests that this phenomenon might also occur in other macrolides. Copyright © 2018. Published by Elsevier Inc.

  18. Youth with special health care needs: transition to adult health care services.

    Science.gov (United States)

    Oswald, Donald P; Gilles, Donna L; Cannady, Mariel S; Wenzel, Donna B; Willis, Janet H; Bodurtha, Joann N

    2013-12-01

    Transition to adult services for children and youth with special health care needs (CYSHCN) has emerged as an important event in the life course of individuals with disabilities. Issues that interfere with efficient transition to adult health care include the perspectives of stakeholders, age limits on pediatric service, complexity of health conditions, a lack of experienced healthcare professionals in the adult arena, and health care financing for chronic and complex conditions. The purposes of this study were to develop a definition of successful transition and to identify determinants that were associated with a successful transition. The 2007 Survey of Adult Transition and Health dataset was used to select variables to be considered for defining success and for identifying predictors of success. The results showed that a small percentage of young adults who participated in the 2007 survey had experienced a successful transition from their pediatric care.

  19. Transition to Adult-Oriented Health Care: Perspectives of Youth and Adults with Complex Physical Disabilities

    Science.gov (United States)

    Young, Nancy L.; Barden, Wendy S.; Mills, Wendy A.; Burke, Tricia A.; Law, Mary; Boydell, Katherine

    2009-01-01

    Introduction: The transition to adulthood is extremely difficult for individuals with disabilities. We sought to explore the specific issue of transition to adult-oriented health care in a Canadian context. Methods: We conducted semi-structured individual interviews with 15 youth and 15 adults with cerebral palsy, spina bifida, and acquired brain…

  20. Energy transition. Between reform and revolution

    International Nuclear Information System (INIS)

    Laville, Bettina

    2014-07-01

    The author comments the content of the French bill project on energy transition. She first discusses the meaning of this concept of energy transition which can be perceived as an evolution, a transformation, a progressive change, rather than a revolution. She recalls the original debate between those who wanted to preserve nuclear energy because it does not produce CO 2 emissions, and those who wanted a more radical change of the energy system. In this respect, she outlines and comments the main statements made by the French President on these issues, and indicates the main measures defined in the bill project regarding the reduction of greenhouse gas emission, the increase of the share of renewable energies, a decrease of the share of nuclear in power production, and a reduction of energy consumption. Then, she discusses how this transition is to be financed, proposes an assessment and a discussion of the skills and shortcomings of the bill project. She notably states that the main shortcoming is the lack of strong objectives regarding the reduction of emissions by transports, and the development of inter-modality. She also regrets the disappearance of the regional public service of energy efficiency, the fact that electricity consumption is not capped. Because of that, it's not that sure that the reduction of greenhouse gas emission by a factor 4 in 2050 with respect to 1990 will be reached. In the next parts, the author discusses the issue of the ecologic tax policy, outlines the importance of being exemplary within the perspective of the 2015 Conference on Climate (COP21)

  1. The strategic year 2015 - international issues analysis

    International Nuclear Information System (INIS)

    Boniface, Pascal; Alex, Bastien; Baccarini, Luca; Bauer, Alain; Bertho, Alain; Bessis, Sophie; Billion, Didier; Brisset, Jean-Vincent; Carlotti, Jean-Etienne; Chaouad, Robert; Delcour, Laure; Dubien, Arnaud; Gobillard, Julie; Hugon, Philippe; Huissoud, Jean-Marc; Jacquemot, Pierre; Kourliandsky, Jean-Jacques; Le Corre, Philippe; Lefeuvre, Georges; Matelly, Sylvie; Maulny, Jean-Pierre; Mazzucchi, Nicolas; Migault, Philippe; Quere, Stephane; Snegaroff, Thomas; Soullez, Christophe

    2014-01-01

    Russian-Ukrainian crisis, assertion of China's power in Asia, jihad threat in Iraq, continued conflict in Syria, withdraw temptation in the US, violence in Central African Republic and Southern Soudan, democracy fatigue in Europe, violent transition in Venezuela and downturn of Latin American giants, the world geopolitical order seems to be undergoing major change. The Strategic year 2015 book aims at understanding and deepening the issues of this change thanks to 197 country fact-sheets, 7 regional sheets, many regional and thematic maps, a chronological recall of the highlights of the year, some bibliographic references and a world statistical yearbook with the essential data. A specific chapter is devoted to climatic change and its consequences on energy and environmental issues

  2. School-to-Work Transitions in the OECD: Do Education Systems Make a Difference?

    Science.gov (United States)

    Karmel, Tom

    2017-01-01

    High unemployment among the young is a concern in many OECD countries. A key issue for policy makers is whether the education system has a role to play in assisting the transition from education to work or whether economic issues dominate. This paper uses OECD country-level data to see whether the structure of countries' education systems,…

  3. Cross-Age Mentoring to Support A-Level Pupils' Transition into Higher Education and Undergraduate Students' Employability

    Science.gov (United States)

    James, Alana I.

    2014-01-01

    Two challenges identified for psychology higher education are supporting entry students' transition, and supporting graduates' transition into employment. The evaluation of the first phase of a cross-age mentoring action research project targeting these issues is presented; eight psychology undergraduates mentored 20 A-level psychology pupils in…

  4. Say Goodbye and Say Hello: The Transition from Pediatric to Adult Gastroenterology

    Directory of Open Access Journals (Sweden)

    Jorge L Pinzon

    2004-01-01

    Full Text Available Pediatric and adult gastroenterologists have identified an important issue to be addressed which entails the process of transition of care for youth affected by chronic gastrointestinal disorders. The adolescent years are a time of change and development, and may be significantly affected by conditions such as Crohn's disease or ulcerative colitis. Health care providers need to advocate and provide comprehensive, developmentally appropriate care for youth and families to facilitate the transition from the pediatric to the adult setting. The present article will review important aspects of the transition from the pediatric to the adult care health system.

  5. Regional debate on energy transition - 17 May 2013

    International Nuclear Information System (INIS)

    Gay, Michel

    2013-01-01

    In this conference, the author discusses the objectives of energy transition in France, and the objectives of the debate on this issue, and addresses three important questions raised by this issue: how to move towards energy efficiency and energy sobriety, which pathway to reach the targeted energy mix in 2025, which are the costs, benefits and financing of energy transition. He describes the complexity of the problem and its contradictory aspects (how to produce more energy with less oil, gas and coal). As far as the first question is concerned (energy efficiency and sobriety), he discusses the notion of energy sobriety, what is at stake (supply security, economic, social and climatic challenges), the strategic objectives, the evolution of energy consumption and production, the leading role of electricity, the CO 2 emissions by different economic sectors, the level of energy imports, the issue of electricity price. As far as the two other questions are concerned, he discusses the opportunities associated with the building and transport sectors, the issue of energy storage, and the role of EDF. In a second part, the author criticizes the Negawatt scenario, and the ADEME's position and action, and discusses opportunities related to energy efficiency, the decrease of the use of fossil energy, the promotion of electricity, and the preservation of nuclear energy as a French asset. He comments the statements of French political actors, the evolution of wind energy production in Europe, the low level of energy and electricity production by the French wind turbines. He discusses a comparison between coal and nuclear in terms of production and pollution, the issue of nuclear waste management, the perspectives for nuclear reactors, the situation in other countries (Switzerland, Germany). He notably outlines that phasing out nuclear in Germany results in the use of coal plants and gas imports

  6. For a rational energy transition based on nuclear energy

    International Nuclear Information System (INIS)

    Chalmin, Philippe

    2014-06-01

    After having recalled the meaning of the concept of energy transition, and stated that this concept is a fuzzy one, this paper addresses the issue of the future of energy through the concept of Energy returned on Energy invested (EROI). It discusses this approach by outlining that energy is the initial driver of economy, and by showing that only hydroelectricity, coal, nuclear and wind energy have a sufficient return rate, and that shale gas is an energy source for the short and medium term. Then, based on data related to world energy resources and consumption, to electric power production from various sources, to pollution health impacts, to electricity prices for industries and for households, it discusses the sustainability of the energy mix regarding energy reserves, health issues, and economic issues. Some examples (Spain, Germany) illustrate economic problems faced by some renewable energies. Finally, the authors outline that, thanks to its nuclear policy, France is the western country which is the most committed in energy transition. Some proposals are made to support nuclear energy, to reduce the use of fossil energies, to launch an ambitious research policy (on energy storage, on photovoltaic energy, on CO 2 hydrogenation, on hydrogen as a fuel), in favour of energy mixes decided at national levels in Europe

  7. „FRAMES OF TRANSITIONAL JUSTICE: SOME APPLICATION IN INTERGENERATIONAL JUSTICE AND RETROACTIVITY”

    Directory of Open Access Journals (Sweden)

    GABRIEL RADU

    2011-04-01

    Full Text Available The article attempts to evaluate the concept of transitional justice in the sphere of public and academical debates, in different social environments during the transition period in the recent history. The approach will include an overflight over some definitions and interpretation of that concept and an assessment of possible applications of this concept in the reparative (corrective theories during the political transition. The evaluation of operational dimension of transitional justice will focus primarily the moral grounds invoked in political and juridical debates, and will pursue some applications of the transitional justice in intergenerational justice realm and at the level of the institution of retroactivity. Also, the assessment will focus the moral core of the motivation of judicial decisions in the space of positive law debates, concerning the constitutional and normative dimension.Examination of particular aspects of the transition has raised particular interest in the public agenda of romanian political change. Reparation issues in dealing with the past had always occupied a privileged role in public debate, in social and political problems. Justification for corrective measures during transition period were presented on various occasions in different points of view, but tools and proper institutions in generating legitimate formal-political obligations were absent, threatening the strength of the the political stability. Requirements for application of a corrective, reparative justice, appeared as a consequence of subjective awareness of rights and liberties that positive law of the communist system ignored or assign them like law infrigement. An approach of such rights, with their features should be evaluated in the context of both totalitarian and democratic state. A dialogue with the past becomes more necesary and will contribute to the success of any public policy designed for any possible reparation in the future

  8. Special Issue: Book Reviews. Resources for Career Management, Counseling, Training and Development.

    Science.gov (United States)

    Horvath, Clara, Ed.; And Others

    1995-01-01

    This special issue includes reviews of 32 books on the following topics: management, human resources, and organizational development; career counseling, guidance, and assessment; job search; resumes; careers in specific fields; careers for special populations; career transitions; and finding balance. (SK)

  9. Phase Transition to an Opaque Plasma in a Sonoluminescing Bubble

    Science.gov (United States)

    Kappus, Brian; Khalid, Shahzad; Chakravarty, Avik; Putterman, Seth

    2011-06-01

    Time-resolved spectrum measurements of a sonoluminescing Xe bubble reveal a transition from transparency to an opaque Planck blackbody. As the temperature is <10000K and the density is below liquid density, the photon scattering length is 10 000 times too large to explain its opacity. We resolve this issue with a model that reduces the ionization potential. According to this model, sonoluminescence originates in a new phase of matter with high ionization. Analysis of line emission from Xe* also yields evidence of phase segregation for this first-order transition inside a bubble.

  10. The detection of microorganisms related to urethritis from the oral cavity of male patients with urethritis.

    Science.gov (United States)

    Le, Phuong Thi; Hamasuna, Ryoichi; Matsumoto, Masahiro; Furubayashi, Keiichi; Hatanaka, Masayuki; Kawai, Shuichi; Yamaguchi, Takamasa; Uehara, Kazutaka; Murakami, Norihiko; Yoshioka, Masaru; Nakayama, Ken; Shiono, Yutaka; Muraoka, Keisuke; Suzuki, Masahiko; Fujimoto, Naohiro; Matsumoto, Tetsuro

    2017-10-01

    To investigate the presence of microorganisms related to urethritis in the oral cavity of male patients with urethritis and the efficacies of antimicrobials for urethritis on microorganisms in the oral cavity. Ninety-two male patients with urethritis and 17 male controls participated to this study at 12 urology clinics in Japan between March 2014 and March 2015. The first voided urine (FVU) and oral wash fluid (OWF) specimens were collected from the participants. The microorganisms in both FVU and OWF specimens were detected by nucleic acid amplification tests at the first and follow-up visit. The efficacies of antimicrobials were evaluated after 1-4 weeks treatment completion. In a total of 92 male patients with urethritis, Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum, Ureaplasma parvum, Trichomonas vaginalis and Gardnerella vaginalis were detected from OWF specimens of 12%, 3%, 9%, 0%, 12%, 3%, 3% and 15% patients, respectively. From control males, no microorganism was detected from OWF specimens. Among 46 patients who could be evaluated for antimicrobial efficacies at the follow-up visit, 5 in FVU specimens failed by azithromycin (AZM), and 10 failed in OWF specimens (7 by AZM, 2 by tetracycline, 1 by spectinomycin; p = 0.002). Especially, a high prevalence of G. vaginalis remained positive after treatment for urethritis in the oral cavity. Microorganisms related to urethritis were detected in the oral cavity of male patients with urethritis. Antimicrobials that focused on urethritis, especially AZM regimen seem to be less effective for microorganisms in the oral cavity. Copyright © 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  11. The second demographic transition: a concise overview of its development.

    Science.gov (United States)

    Lesthaeghe, Ron

    2014-12-23

    This article gives a concise overview of the theoretical development of the concept of the "second demographic transition" since it was coined in 1986, its components, and its applicability, first to European populations and subsequently also to non-European societies as well. Both the demographic and the societal contrasts between the first demographic transition (FDT) and the second demographic transition (SDT) are highlighted. Then, the major criticisms of the SDT theory are outlined, and these issues are discussed in the light of the most recent developments in Europe, the United States, the Far East, and Latin America. It turns out that three major SDT patterns have developed and that these evolutions are contingent on much older systems of kinship and family organization.

  12. Understanding L-H transition in tokamak fusion plasmas

    Science.gov (United States)

    Xu, Guosheng; Wu, Xingquan

    2017-03-01

    This paper reviews the current state of understanding of the L-H transition phenomenon in tokamak plasmas with a focus on two central issues: (a) the mechanism for turbulence quick suppression at the L-H transition; (b) the mechanism for subsequent generation of sheared flow. We briefly review recent advances in the understanding of the fast suppression of edge turbulence across the L-H transition. We uncover a comprehensive physical picture of the L-H transition by piecing together a number of recent experimental observations and insights obtained from 1D and 2D simulation models. Different roles played by diamagnetic mean flow, neoclassical-driven mean flow, turbulence-driven mean flow, and turbulence-driven zonal flows are discussed and clarified. It is found that the L-H transition occurs spontaneously mediated by a shift in the radial wavenumber spectrum of edge turbulence, which provides a critical evidence for the theory of turbulence quench by the flow shear. Remaining questions and some key directions for future investigations are proposed. This work was supported by National Magnetic Confinement Fusion Science Program of China under Contracts No. 2015GB101000, No. 2013GB106000, and No. 2013GB107000 and National Natural Science Foundation of China under Contracts No. 11575235 and No. 11422546.

  13. Research for the energy transition. The organization of the energy systems; Forschung fuer die Energiewende. Die Gestaltung des Energiesystems

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-03-15

    The volume on research for the energy transition includes contributions to the FVEE annual meeting 2016 concerning the following issues: status and perspectives of the energy transition, key technologies for the energy transition, political boundary conditions, development trends in photovoltaics, components for the energy supply (wind energy, hydrogen technologies, smart bioenergy concept, contribution of the geosphere), grids and storage systems for the energy transition, research network renewable energies.

  14. Transitional fossils and the origin of turtles.

    Science.gov (United States)

    Lyson, Tyler R; Bever, Gabe S; Bhullar, Bhart-Anjan S; Joyce, Walter G; Gauthier, Jacques A

    2010-12-23

    The origin of turtles is one of the most contentious issues in systematics with three currently viable hypotheses: turtles as the extant sister to (i) the crocodile-bird clade, (ii) the lizard-tuatara clade, or (iii) Diapsida (a clade composed of (i) and (ii)). We reanalysed a recent dataset that allied turtles with the lizard-tuatara clade and found that the inclusion of the stem turtle Proganochelys quenstedti and the 'parareptile' Eunotosaurus africanus results in a single overriding morphological signal, with turtles outside Diapsida. This result reflects the importance of transitional fossils when long branches separate crown clades, and highlights unexplored issues such as the role of topological congruence when using fossils to calibrate molecular clocks.

  15. Information technology deployment in a transition economy: Results from Slovenia

    Directory of Open Access Journals (Sweden)

    Hovelja Tomaž

    2009-01-01

    Full Text Available Information technology (IT is increasingly establishing itself as one of the major topics of study in the OECD area. The resulting OECD studies found that IT has an enormous productive potential; however before an economy can gain most of IT's benefits, several challenges need to be successfully addressed. The key challenges these studies identified are adequate organizational transformations of the enterprises and adequate reorganization of key national institutions. How these two challenges are tackled by the economies that are going through the transition from a socialist towards a coordinated/liberal market economy is, unfortunately, not equally well documented. To improve this situation in this paper I present new findings from one transition economy concerning the issues that the developed OECD countries already highlighted as critical for the successful deployment of IT, and issues that seem specific to the transition environments. The presented findings are based on the study I conducted into 94 enterprises, representing the population of the 914 biggest added value generating enterprises in Slovenia. This article thus tries to allow Slovenia and other economies in a similar situation to draw broad and important conclusions with managerial and political implications on how to deploy all available IT potential.

  16. An Ordered Regression Model to Predict Transit Passengers’ Behavioural Intentions

    Energy Technology Data Exchange (ETDEWEB)

    Oña, J. de; Oña, R. de; Eboli, L.; Forciniti, C.; Mazzulla, G.

    2016-07-01

    Passengers’ behavioural intentions after experiencing transit services can be viewed as signals that show if a customer continues to utilise a company’s service. Users’ behavioural intentions can depend on a series of aspects that are difficult to measure directly. More recently, transit passengers’ behavioural intentions have been just considered together with the concepts of service quality and customer satisfaction. Due to the characteristics of the ways for evaluating passengers’ behavioural intentions, service quality and customer satisfaction, we retain that this kind of issue could be analysed also by applying ordered regression models. This work aims to propose just an ordered probit model for analysing service quality factors that can influence passengers’ behavioural intentions towards the use of transit services. The case study is the LRT of Seville (Spain), where a survey was conducted in order to collect the opinions of the passengers about the existing transit service, and to have a measure of the aspects that can influence the intentions of the users to continue using the transit service in the future. (Author)

  17. Market transition or path dependency? Changing effects of income determinants in the Czech Republic, Hungary, Poland, Russia, and Slovakia, 1991–2002

    NARCIS (Netherlands)

    Verhoeven, Willem-Jan; Dessens, Jos; Jansen, Wim

    2008-01-01

    A major issue in the market transition debate on transitional societies is the extent to which changing economic institutions are responsible for the changing stratification order in post-Communist societies, as assumed by the Market Transition Theory (MTT). Advocates of path dependent

  18. Molybdenum-gold proximity bilayers as transition edge sensors for microcalorimeters and bolometers

    International Nuclear Information System (INIS)

    Chen, T.C.; Bier, A.; DiCamillo, B.; Finkbeiner, F. M.

    1999-01-01

    Mo/Au proximity bilayers as transition edge sensors (TESs) are promising candidates for low-temperature thermometry. The transition temperature of the bilayers can be easily tuned between 50 and 600 mK, yielding sensors which can be used in a variety of calorimetric and bolometric applications. With phase transition widths of less than 1 mK, Mo/Au TESs show very high temperature sensitivity (d(logR)/d(logT)∼2500). Also, Mo/Au TESs show improved thermal and chemical stability compared to most other bilayer configurations. Fabrication issues and detector performance of Mo/Au TESs on Si 3 N 4 membranes are discussed. (author)

  19. Adolescent Mothers in a Transitional Living Facility: An Exploratory Study of Support Networks and Attachment Patterns

    Science.gov (United States)

    Schwartz, Ann E.; McRoy, Ruth G.; Downs, A. Chris

    2004-01-01

    Most of the research literature on attachment and adolescent transitions has addressed youth in family settings. This article explores these issues with a sample of 25 pregnant and parenting teens living in a transitional shelter. Using case records and interview data as well as results of standardized measures of depression, self-esteem, child…

  20. Petroleum marketing in Africa. Issues in pricing, taxation and investment

    International Nuclear Information System (INIS)

    Bhagavan, M.R.

    1999-01-01

    This four part book examines and compares the liberalised petroleum marketing in Kenya with petroleum marketing in Ethiopia which has just begun the transition from state control to liberalisation. The petroleum sub-sector in both countries is put into context, and petroleum pricing and taxation issues, financing, marketing issues and policy are reviewed, and policy recommendations for both countries are given. The comparative analysis of the Ethiopian and Kenyan situations presented highlights some lessons for sub-Saharan Africa. Information and statistics on petroleum, marketing, and investment in sub-Saharan Africa are given in the appendix. (UK)

  1. Determination of the Tc distribution for 1000 Transition Edge Sensors

    International Nuclear Information System (INIS)

    Brink, P.L.; Saab, T.; Miller, A.J.; Cabrera, B.; Castle, J.P.; Chang, C.; Young, B.A.; Akerib, D.S.; Discroll, D.; Kamat, S.; Perera, T.A.; Schnee, R.W.; Wang, G.; Emes, J.H.; Gaitskell, R.J.; Mandic, V.; Meunier, P.; Rau, W.; Sadoulet, B.; Seitz, D.N.

    2002-01-01

    The ZIP detectors deployed in the CDMS II experiment utilize phonon sensors comprising W Transition Edge Sensors (TESs). In order to ensure uniform collection of the athermal phonon signal the TESs are dispersed uniformly on one side of a 1 cm thick, 3 inch diameter, disk. Each quadrant contains 1036 TESs connected in parallel to one series-array SQUID amplifier. The initial superconducting transition temperatures of these TESs tend to be too high for our requirements, and substantial gradients make the operation of the detectors difficult. Hence our implementation of Fe-56 ion implantation, as reported at the previous LTD meeting, to reduce in a controlled manner the transition temperature. However, the successful implementation of this ion-implantation scheme requires accurate knowledge of the initial transition temperature of each TES in a given quadrant. We report on our approaches and techniques employed to address the issue of determining the initial Tc distribution

  2. Northern Ireland in Transition: The Role of Justice

    Directory of Open Access Journals (Sweden)

    Christian Mailhes

    2005-03-01

    Full Text Available All post-conflict societies switching to constitutional liberal democracies have to deal with their past through transitional justice mechanisms that offer to hear the victims, try the perpetrators of all types of abuses, introduce peace and reconciliation schemes. It is time for state and non-state organs to account for past crimes. Several countries have successfully tested such mechanisms. Northern Ireland is the ideal ground for transitional justice to operate but it dispels foreign tailor-made models. However, a number of major reforms and projects have addressed sensitive issues in the wake of the Good Friday Agreement. Two key institutions, the police and the criminal justice system, whose responsibility in the conflict was undeniable, have been reformed. Law and lawyers are concerned with these changes and the introduction of a Human Rights culture in Northern Ireland. A clear break with the past must be achieved for transitional justice mechanisms to work successfully.

  3. Application of Kissinger analysis to glass transition and study of ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. Application of Kissinger analysis to glass transition and study of thermal degradation kinetics of phenolic–acrylic IPNs ... Author Affiliations. S Goswami1 K Kiran1. Department of Polymer Engineering, Birla Institute of Technology, Ranchi 835 215, India ...

  4. AcEST: DK955248 [AcEST

    Lifescience Database Archive (English)

    Full Text Available _BSNV Structural polyprotein OS=Blotched snakehead virus Align length 54 Score (b...|POLS_BSNV Structural polyprotein OS=Blotched snakehead... 31 1.7 sp|Q7XWS7|FH12_...sphatase non-receptor ... 29 8.4 >sp|Q8AZM0|POLS_BSNV Structural polyprotein OS=Blotched snakehead virus PE=

  5. School-to-Work Transitions in Mongolia

    Directory of Open Access Journals (Sweden)

    Pastore, Francesco

    2009-12-01

    Full Text Available Relatively little is known about the youth labour market in Mongolia. This paper addresses the issue by taking advantage of a recent ad hoc School to Work Transition Survey (SWTS on young people aged 15-29 years carried out in 2006. After a period of sharp reduction in the 1990s, educational attainment is increasing, as compared to other countries in the area. Nonetheless, important constraints seem to affect the supply of education, especially in rural areas. In addition, as application of the new ILO school-to-work transition classification shows, the country is unable to provide young people with a sufficient number of decent jobs. This translates into high youth unemployment in urban areas and very low productivity jobs in rural areas. Mincerian estimates confirm that human capital is an important determinant of earnings in urban, but not in rural areas

  6. Modelling multimodal transit networks : integration of bus networks with walking and cycling

    NARCIS (Netherlands)

    Brand, Judith; Hoogendoorn, S.P.; van Oort, N.; Schalkwijk, Bart

    2017-01-01

    Demand for (public) transportation is subject to dynamics affected by technological, spatial, societal and demographic aspects. The political environment, together with financial and spatial constraints limit the possibilities to address transit issues arising from growing demand through the

  7. Study of the Successes, Pitfalls, and Outcomes of Transition Programs Working within the Consortium for Public Education

    Science.gov (United States)

    Della Lucia, Eric David

    2011-01-01

    Transition is a concern for children moving from the eighth grade into high school. Students experience difficulty with grades, behavior, and emotional transitions at that juncture in their education. The trend can be observed both across the nation and locally in western Pennsylvania. This paper gives evidence of the national issues that students…

  8. Power sector restructuring in West Africa. The issues

    International Nuclear Information System (INIS)

    Turkson, J.

    1997-01-01

    At independence, most countries in the West Africa sub-region adopted a development strategy which was spearheaded by the public sector. The aims at presenting discussions on some of the major issues on initiating the reform process and issues associated with the transition period. Section 2 looks at the energy resources for power development in the region and section 3 discusses some unsustainable trends in the sector. Section 4 presents the issues and discusses them, and finally, section 5 presents the conclusion and some policy implications. The discussions in the paper stress the point that reforming the power sector in the countries in the region is not simply a question of implementing consultants' recommendations, but rather a process that must be thought through, and also involves bringing all the shareholders along and putting the regulatory system and institution in place to ensure acceptability and implementatibility of the proposed changes. Governments in the region have a responsibility to build the capacity necessary to initiate and manage the reform process in the power sector, and understanding the issues involved will help to adopt the right approach to reforming the sector. (ARW) 11 refs

  9. Clean energy for Europe in transition

    International Nuclear Information System (INIS)

    Zaleski, C.P.

    1992-01-01

    Energy, an important subject, cannot be validly discussed alone. For some time already, most experts agree that is necessary to include the environmental effects if one seeks a valid discussion. It appears now this was especially pointed out by the dramatic changes in Russia and other Eastern and Central European countries that the only efficient way to discuss energy is even more global. That discussion should, of course, include economics and the politico-economic system, but also society-people's motivations, mentality, education and finally a touch of philosophy, notably value systems. The debates of the third MIEC conference were characterized by their interdisciplinary character. The organizers tried to address these different issues by having them discussed together while emphasizing in different sessions specific aspects like economics and political system society, education, and value system and finally scientific and technical aspects of new energy technology. This meeting presents 28 papers of which 15 are in the INIS and Energy database scope. In the first and the second issue, the subject studied is energy policy in transition economy. The third issue describes the relationships between energy, environment and society. In the two last issues, the problems of safety in nuclear industry are studied

  10. Freedom of Expression: Importing European & US Constitutional Models in Transitional Democracies

    NARCIS (Netherlands)

    Belavusau, U.

    2013-01-01

    This book considers the issue of free speech in transitional democracies focusing on the socio-legal developments in the Czech Republic, Hungary, and Poland. In showing how these Central and Eastern European countries have engaged with free speech models imported from the Council of Europe / EU and

  11. Transitive Credit and JSON-LD

    Directory of Open Access Journals (Sweden)

    Daniel S. Katz

    2015-11-01

    Full Text Available Science and engineering research increasingly relies on activities that facilitate research but are not currently rewarded or recognized, such as: data sharing; developing common data resources, software and methodologies; and annotating data and publications. To promote and advance these activities, we must develop mechanisms for assigning credit, facilitate the appropriate attribution of research outcomes, devise incentives for activities that facilitate research, and allocate funds to maximize return on investment. In this article, we focus on addressing the issue of assigning credit for both direct and indirect contributions, specifically by using JSON-LD to implement a prototype transitive credit system.

  12. Navy-Wide Personnel Survey (NPS) 1992: Statistical Tables for Officers

    Science.gov (United States)

    1993-08-01

    PERCENTS DO NOT KNOW OPTION OMITTED 440 OFFICER 2693 LUDRSUIP: WORK GROUP LZSTIS AND RZEPCDS TO NY PROULDS Q1 azm KALE FEMALE DONT KNOW 3.0% 3.0% N 97 15...dining facilities make 3.1 Yes, other military service training available fruit, vegetables , 11.8 Yes, civilian (local community) training. low fat meat

  13. Bill project on energy transition for a green growth - Nr 2188. Impact study

    International Nuclear Information System (INIS)

    Valls, Manuel; Royal, Segolene

    2014-01-01

    This document first proposes a statement by the Minister on Ecology on the motivations of the French bill project on energy transition which notably addresses the development of new energies, expresses a strong political commitment on energy, addresses the big issue of energy saving (with objectives of job creation and price reduction in the building sector), promotes a development of renewable energies based on local resources, aims at the emergence of citizen participation in energy choices and issues. The content of the bill project is then commented. The main addressed issues are: to define common objectives for a successful energy transition, an energy independence and for the struggle against climate change, a better renovation of buildings to save energy, to reduce prices and to create jobs, to develop clean transports to improve air quality and to protect health, to struggle against energy wastes and to promote circular economy, to promote renewable energies, to strengthen nuclear safety and citizen information, to simplify and clarify procedures, to enable citizens, local communities and the State to act together. The document then proposes the text of the bill project. A second part is a report of an impact study of these different issues and objectives addressed in the bill project

  14. Turner syndrome: transition from pediatrics to adulthood.

    Science.gov (United States)

    Rubin, Karen R

    2008-09-01

    To highlight the importance of an improved, seamless, and effective transition from pediatric to adult care, especially for medically complex conditions such as Turner syndrome (TS). The morbidities in adult patients with TS are reviewed, including features of the metabolic syndrome, congenital and acquired cardiovascular conditions, osteopenia and osteoporosis, autoimmune thyroid disease, and obesity, and psychobehavioral issues are addressed, in terms of promoting the development of independent self-care and autonomy in adolescent patients. An essential component of high-quality health care, transition for adolescents with TS needs to be reengineered as a staged process initiated during early-stage adolescence (about age 12 years), when exogenous estrogen therapy is begun in coordination with the final phase of growth hormone therapy. At this time, the focus of care shifts from the parent to the adolescent and from maximizing final adult height to inducing puberty with gradually increasing doses of estrogen. During this transition, the development of healthful and independent healthcare behaviors should be promoted to prepare patients with TS for the adult responsibility of self-care. During the final phase of transition, an adult care plan should be formulated in collaboration with the adolescent with TS and her providers of adult care to improve the likelihood that she will continue to be carefully monitored in a way that optimizes her adult health and longevity. The transitional period from pediatrics to adulthood is the ideal time for patients with TS to be made aware of their health history and health needs and of the evolving impact of TS into adulthood.

  15. Exploring the transition from student to practitioner in diagnostic radiography

    International Nuclear Information System (INIS)

    Naylor, S.; Ferris, C.; Burton, M.

    2016-01-01

    Introduction: This study explores the expectations and experiences of newly qualified diagnostic radiographers during their transition into practice. Methods: This was a longitudinal study using interpretative phenomenological analysis methodology. Data were gathered from four students who participated in a focus group. This informed semi structured interviews with a further eight students who were interviewed prior to starting work and three times over the following twelve months. Results: Themes generated from the data included; experience, fitting in, and identity. Conclusion: This study brings to light the experiences of newly qualified diagnostic radiographers. The findings are open to theoretical generalizability and raise issues that may be used by academic staff in the preparation of students and managers who support newly qualified staff members. - Highlights: • Diagnostic radiographers are well prepared for most clinical practice. • Clinical education cannot fully prepare students for the reality of practice. • Being familiar with a hospital, and staff, reduces the stress of starting work. • Newly qualified radiographers struggle taking responsibility for students. • Professional identity is a key issue in the transition from student to practitioner.

  16. Personality and Relationship Quality During the Transition From High School to Early Adulthood

    Science.gov (United States)

    Parker, Philip D.; Lüdtke, Oliver; Trautwein, Ulrich; Roberts, Brent W.

    2013-01-01

    The post–high school transition period is believed to be associated with considerable changes in social networks, yet longitudinal studies documenting these changes are scarce. To address this gap, the current research explored 3 relevant issues. First, changes in participants’ relationship characteristics during the transition from high school were examined. Second, the roles of personality traits as antecedents of these changes were studied. Third, the association between change in relationship characteristics and personality during the transition was explored. A sample of over 2,000 German emerging adults, surveyed before leaving school and then 2 years after the transition from high school, was assessed on personality traits and a multidimensional assessment of the quality of their relationships. Findings indicated that participants experienced mostly positive changes in relationship quality during the transition from high school and that antecedent personality at school was an important predictor of the nature of this change. Finally, change in relationship quality was found to be associated with personality change during the post-school transition. Findings indicated that personality traits may influence transition success and that change in relationships during this transition may influence personality development. The implications of the research for post-school transition success are discussed. PMID:22224909

  17. Preliminary Exploration of Encounter During Transit Across Southern Africa

    Energy Technology Data Exchange (ETDEWEB)

    Stroud, Phillip David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cuellar-Hengartner, Leticia [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kubicek, Deborah Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cleland, Timothy James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-28

    Los Alamos National Laboratory (LANL) is utilizing the Probability Effectiveness Methodology (PEM) tools, particularly the Pathway Analysis, Threat Response and Interdiction Options Tool (PATRIOT) to support the DNDO Architecture and Planning Directorate’s (APD) development of a multi-region terrorist risk assessment tool. The effort is divided into three stages. The first stage is an exploration of what can be done with PATRIOT essentially as is, to characterize encounter rate during transit across a single selected region. The second stage is to develop, condition, and implement required modifications to the data and conduct analysis to generate a well-founded assessment of the transit reliability across that selected region, and to identify any issues in the process. The final stage is to extend the work to a full multi-region global model. This document provides the results of the first stage, namely preliminary explorations with PATRIOT to assess the transit reliability across the region of southern Africa.

  18. Fluorescence Imaging Study of Transition in Underexpanded Free Jets

    Science.gov (United States)

    Wilkes, Jennifer A.; Danehy, Paul M.; Nowak, Robert J.

    2005-01-01

    Planar laser-induced fluorescence (PLIF) is demonstrated to be a valuable tool for studying the onset of transition to turbulence. For this study, we have used PLIF of nitric oxide (NO) to image underexpanded axisymmetric free jets issuing into a low-pressure chamber through a smooth converging nozzle with a sonic orifice. Flows were studied over a range of Reynolds numbers and nozzle-exit-to-ambient pressure ratios with the aim of empirically determining criteria governing the onset of turbulence. We have developed an image processing technique, involving calculation of the standard deviation of the intensity in PLIF images, in order to aid in the identification of turbulence. We have used the resulting images to identify laminar, transitional and turbulent flow regimes. Jet scaling parameters were used to define a rescaled Reynolds number that incorporates the influence of a varying pressure ratio. An empirical correlation was found between transition length and this rescaled Reynolds number for highly underexpanded jets.

  19. Pluri-annual energy programming - The Energy transition for green growth. Synthesis

    International Nuclear Information System (INIS)

    2016-01-01

    The Energy Transition for Green Growth Act and its attendant action plans are designed to give France the means to make a more effective contribution to tackling climate change and reinforce its energy independence, while striking a better balance in its energy mix and creating jobs and business growth. This document summarizes the content of the Pluri-annual energy programming, which is the consistent action framework of the French energy transition: improving energy efficiency and reducing fossil fuels consumption, accelerating the development of renewable energy sources, maintaining a high-level of security of supply in the respect of environmental requirements, preparing tomorrow's energy system, developing clean mobility, taking account of the socio-economic issues of the energy transition and acting with the regions in this way

  20. DEMOCRATIZATION AND POLITICAL TRANSITION IN ARAB WORLD: PROSPECTS AND CHALLENGES

    Directory of Open Access Journals (Sweden)

    Ibrahim Kawuley Mikail

    2015-12-01

    Full Text Available Democracy and Democratization process was among the top priorities in the new post-cold war global agenda. This issue has convinced some undemocratic countries of Arab World to set up in quest for democracy and to assertively demand their long-denied socio-economic and political justice by the autocratic rulers for the region. Indeed, the current Arab spring is geared towards transition from undemocratic system (i.e. Monarchy and Military dictatorship to democracy. Secondary data was adopted in this study. The study revealed that humiliation, prolong monarchy/military dictatorship, lack of economic reform, globalization and proliferation of mass literacy were among the factors responsible for political transition in the region. Meanwhile, establishment of tenets of democracy (i.e. rules of law, human rights, freedom, etc. and insecurity, external domination and loss of lives were among the prospect and challenges of the transition. The paper recommended among others that there is need for political and economic reform in the Arab countries which would lead to transit to democracy.

  1. Note on french law on the energy transition and green growth

    International Nuclear Information System (INIS)

    Denolle, Anne-Sophie

    2016-01-01

    The French law on the energy transition and green growth (TECV law) seems in some ways limited in scope, restricted to set vague goals and formulate simple incentives to act. But this law can not be reduced to this. Composed of 215 articles, it necessarily refers to prescriptive and technical measures meant to realize the energy transition. The TECV law has, moreover, the merit of addressing the energy issue in its entirety, evoking not only renewable energies, but also the insulation of buildings, the challenge of developing clean transport, the need to promote a circular economy that consumes less energy

  2. Energy transitions in France: lessons learned from prospective studies. Contribution to the National Debate on Energy Transition

    International Nuclear Information System (INIS)

    Bibas, Ruben; Hourcade, Jean-Charles

    2013-01-01

    After having outlined that the debates on energy transition in France focus on three main issues (management of greenhouse gas emissions, future of nuclear within the French energy mix, energy security), the authors report the use of the Imaclim-R France model (a multi-sector recursive hybrid model) which is adapted to sensitivity studies for the whole set of hypotheses. As energy parameters, they use data provided by ENCILOWCARB scenarios from a European project (Engaging civil society in low carbon scenarios). After having examined that they are not sufficient to conduct a transition strategy leading to a F4 pathway of reduction of greenhouse gas emissions and/or a progressive phasing out nuclear, they consider the policies which are necessary to mobilise potentials of energy saving and emission reduction. Several scenarios are studied in terms of energy and environmental performances and in terms of economic and social performances: scenarios based on policies and measures with or without additional component (carbon tax, social negotiation, carbon finance)

  3. Molecular modeling and multiscaling issues for electronic material applications

    CERN Document Server

    Iwamoto, Nancy; Yuen, Matthew; Fan, Haibo

    Volume 1 : Molecular Modeling and Multiscaling Issues for Electronic Material Applications provides a snapshot on the progression of molecular modeling in the electronics industry and how molecular modeling is currently being used to understand material performance to solve relevant issues in this field. This book is intended to introduce the reader to the evolving role of molecular modeling, especially seen through the eyes of the IEEE community involved in material modeling for electronic applications.  Part I presents  the role that quantum mechanics can play in performance prediction, such as properties dependent upon electronic structure, but also shows examples how molecular models may be used in performance diagnostics, especially when chemistry is part of the performance issue.  Part II gives examples of large-scale atomistic methods in material failure and shows several examples of transitioning between grain boundary simulations (on the atomistic level)and large-scale models including an example ...

  4. Land Use Transition and Human Health in the context of Climate ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Land Use Transition and Human Health in the context of Climate Change in the Eastern Himalayas. Land use change is ... it at the communal level. The overall goal is to reduce the vulnerability of mountain people to health issues caused by land use change using ecosystem approaches to human health (Ecohealth).

  5. The role of the environmental industry in Europe's ecological transition

    International Nuclear Information System (INIS)

    Frerot, Antoine

    2013-01-01

    Europe must embark on a path leading to a virtuous ecological transition if it is to achieve further economic growth that does not harm the environment. This transition must address issues such as resource scarcity, the increasing complexity of pollution and the challenges posed by new ways of living in our cities. Environmental services have an important role to play by providing the operational solutions needed to make this transition and by creating new economic models that reward performance rather than volumes sold. Local and national governments have the ability and the duty to assist in the real-life deployment of such solutions by setting clear rules and targets, using the power of public procurement and helping to put financing in place. (author)

  6. Transitional Justice

    DEFF Research Database (Denmark)

    Gissel, Line Engbo

    This presentation builds on an earlier published article, 'Contemporary Transitional Justice: Normalising a Politics of Exception'. It argues that the field of transitional justice has undergone a shift in conceptualisation and hence practice. Transitional justice is presently understood to be th...... to be the provision of ordinary criminal justice in contexts of exceptional political transition.......This presentation builds on an earlier published article, 'Contemporary Transitional Justice: Normalising a Politics of Exception'. It argues that the field of transitional justice has undergone a shift in conceptualisation and hence practice. Transitional justice is presently understood...

  7. Point Climat no. 29 'Managing France's energy transition while safeguarding economic competitiveness: be productive'

    International Nuclear Information System (INIS)

    Sartor, Oliver; Leguet, Benoit

    2013-01-01

    Among the publications of CDC Climat Research, 'Climate Briefs' presents, in a few pages, hot topics in climate change policy. This issue addresses the following points: - Is the French energy transition compatible with economic growth and a 'competitive' French economy? Our answer is 'yes, with some conditions'. - The French economy is better positioned today for a meaningful energy transition than it has been for over 40 years. At the level of the macro-economy, a steady shift to higher energy prices is now much easier without hurting economic growth than it once was. - A small percentage of energy-intensive sectors may need targeted and temporary assistance with this transition

  8. 'Sauvons le Climat' submits to the attention of the CNDTE: NEGATEP and some recommendations for a 'climatically correct' energy transition - Participation notebook issued by Sauvons le Climat for the National Commission on Energy Transition

    International Nuclear Information System (INIS)

    2013-01-01

    As a drastic reduction of the combustion of fossil energies is considered by Sauvons le Climat as the first priority for energy transition, this document evokes the European objectives in terms of reduction of greenhouse gas emissions, outlines the need of new balance for the energy mix, of a development of renewable energies, of a replacement of fossil energies, and of a new balance for subsidies awarded to renewable energies. The next part discusses the NEGATEP scenario which is associated with these objectives of phasing out fossil energies. The author comments the current energy mix in terms of electricity production, and the evolution perspectives according to a reference scenario. They detail the NEGATEP scenario (final consumption in the main sectors, energy sources with fossil fuels divided by 4 and thermal renewable energies multiplied by 4, a 54 pc increase of electricity production), discuss the share of renewable production of electricity, the share of nuclear production, and how to face the varying demand from the grid. They discuss some major issues regarding the evolution of energy consumption of the main sectors (housing and office building, transports, agriculture and industry)

  9. A Qualitative Study of Patient and Provider Experiences during Preoperative Care Transitions

    Science.gov (United States)

    MALLEY, ANN; YOUNG, GARY J.

    2017-01-01

    Aims To explore the issues and challenges of care transitions in the preoperative environment. Background Ineffective transitions play a role in a majority of serious medical errors. There is a paucity of research related to the preoperative arena and the multiple inherent transitions in care that occur there. Design Qualitative descriptive design was used. Methods Semi-structured interviews were conducted in a 975 bed academic medical center. Results 30 providers and 10 preoperative patients participated. Themes that arose were: (1) Need for clarity of purpose of preoperative care (2) Care coordination (3) Inter-professional boundaries of care (4) Inadequate time and resources. Conclusion Effective transitions in the preoperative environment require that providers bridge scope of practice barriers to promote good teamwork. Preoperative care that is a product of well-informed providers and patients can improve the entire perioperative care process and potentially influence post-operative patient outcomes. Relevance to Clinical Practice Nurses are well positioned to bridge the gaps within transitions of care and accordingly affect health outcomes. PMID:27706872

  10. Strategies to address transition costs in the electricity industry

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, L.; Hadley, S.; Hirst, E.

    1996-07-01

    Transition costs are the potential monetary losses that electric- utility shareholders, ratepayers, or other parties might experience because of structural changes in the electricity industry. Regulators, policy analysts, utilities, and consumer groups have proposed a number of strategies to address transition costs, such as immediately opening retail electricity markets or delaying retail competition. This report has 3 objectives: identify a wide range of strategies available to regulators and utilities; systematically examine effects of strategies; and identify potentially promising strategies that may provide benefits to more than one set of stakeholders. The many individual strategies are grouped into 6 major categories: market actions, depreciation options, rate-making actions, utility cost reductions, tax measures, and other options. Of the 34 individual strategies, retail ratepayers have primary or secondary responsibility for paying transition costs in 19 of the strategies, shareholders in 12, wheeling customers in 11, taxpayers in 8, and nonutility suppliers in 4. Most of the strategies shift costs among different segments of the economy, although utility cost reductions can be used to offset transition costs. Most of the strategies require cooperation of other parties, including regulators, to be implemented successfully; financial stakeholders must be engages in negotiations that hold the promise of shared benefits. Only by rejecting ``winner-take-all`` strategies will the transition-cost issue be expeditiously resolved.

  11. SIMMER-II analysis of transition-phase experiments

    International Nuclear Information System (INIS)

    Wehner, T.R.; Bell, C.R.

    1985-01-01

    Analyses of Los Alamos transition-phase experiments with the SIMMER-II computer code are reported. These transient boilup experiments simulated the recriticality-induced transient motion of a boiling pool of molten fuel, molten steel and steel vapor, within a subassembly duct in a liquid-metal fast breeder reactor during the transition phase of a core-disruptive accident. The two purposes of these experiments were to explore and reach a better understanding of fast reactor safety issues, and to provide data for SIMMER-II verification. Experimental data, consisting of four pressure traces and a high-speed movie, were recorded for four sets of initial conditions. For three of the four cases, SIMMER-II-calculated pressures compared reasonably well with the experimental pressures. After a modification to SIMMER-II's liquid-vapor drag correlation, the comparison for the fourth case was reasonable also. 12 refs., 4 figs

  12. Dynamic phase transition in diffusion-limited reactions

    International Nuclear Information System (INIS)

    Tauber, U.C.

    2002-01-01

    Many non-equilibrium systems display dynamic phase transitions from active to absorbing states, where fluctuations cease entirely. Based on a field theory representation of the master equation, the critical behavior can be analyzed by means of the renormalization group. The resulting universality classes for single-species systems are reviewed here. Generically, the critical exponents are those of directed percolation (Reggeon field theory), with critical dimension d c = 4. Yet local particle number parity conservation in even-offspring branching and annihilating random walks implies an inactive phase (emerging below d c = 4/3) that is characterized by the power laws of the pair annihilation reaction, and leads to different critical exponents at the transition. For local processes without memory, the pair contact process with diffusion represents the only other non-trivial universality class. The consistent treatment of restricted site occupations and quenched random reaction rates are important open issues (Author)

  13. Evolving legal framework of corporate governance in India – issues and challenges

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar GUPTA

    2014-12-01

    Full Text Available Investors now started considering corporate governance as very essential factor before investment especially in view of the unstable environment in the securities market. It is considered that good corporate governance inspires, strengthens and maintains investor’s confidence by ensuring company’s commitment to higher growth and profits. Corporate Governance has become a major concern for global economies particularly the transition world. Sound corporate governance is extremely important for transition economies for creation of the key institutions, the private corporations, which drive the successful economic transformation to a market based economy, effective allocation of capital and development of financial markets, attracting foreign investment and making a contribution to the process of national development. The Corporate Governance issue has emerged primarily because of the growing importance of corporations in the national economies and their interaction with the international agencies and institutions. This paper presents the current scenario of corporate governance in India, the evolving legal framework and identified the major issues and challenges that need to be addressed to implement an effective system of corporate governance in India.

  14. Policy Frameworks for Energy Transition in England : Challenges in a Former Industrial City

    NARCIS (Netherlands)

    Rocco de Campos Pereira, R.C.

    2016-01-01

    This paper addresses the make-up and the limitations of a multi-level governance approach in tackling issues of fuel poverty and energy transition connected to poverty in England. Although the English planning framework offers unparalleled opportunities for innovative governance arrangements, and

  15. Langley Stability and Transition Analysis Code (LASTRAC) Version 1.2 User Manual

    Science.gov (United States)

    Chang, Chau-Lyan

    2004-01-01

    LASTRAC is a general-purposed, physics-based transition prediction code released by NASA for Laminar Flow Control studies and transition research. The design and development of the LASTRAC code is aimed at providing an engineering tool that is easy to use and yet capable of dealing with a broad range of transition related issues. It was written from scratch based on the state-of-the-art numerical methods for stability analysis and modern software technologies. At low fidelity, it allows users to perform linear stability analysis and N-factor transition correlation for a broad range of flow regimes and configurations by using either the linear stability theory or linear parabolized stability equations method. At high fidelity, users may use nonlinear PSE to track finite-amplitude disturbances until the skin friction rise. This document describes the governing equations, numerical methods, code development, detailed description of input/output parameters, and case studies for the current release of LASTRAC.

  16. TRANSIT THROUGH THE SCHENGEN AREA FOR THE HOLDERS OF SPECIFIC SWISS DOCUMENTS

    CERN Multimedia

    2006-01-01

    The Swiss Permanent Mission has informed CERN of the following relaxation of the transit regulations granted by the States applying the Schengen Agreement and other European States to third-country nationals who are normally required to obtain a visa. As from 10 July 2006, those holding a Carte de légitimation or Attestation de fonctions issued by the Swiss Federal Department of Foreign Affairs or a B, C or Ci-type residence permit are exempted from the requirement to obtain a visa for transit through the Schengen area, so long as the transit period does not exceed five days (for each transit). For other circumstances (for example tourism, including for conferences), the requirement to obtain a visa remains in force. The States that form the Schengen area are: Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Italy, Luxembourg, Norway, the Netherlands, Portugal, Spain and Sweden. In addition, the following States have decided to apply the same exemption from the requirement to obtain a...

  17. Quality in transitional care of the elderly: Key challenges and relevant improvement measures

    Directory of Open Access Journals (Sweden)

    Marianne Storm

    2014-05-01

    Full Text Available Introduction: Elderly people aged over 75 years with multifaceted care needs are often in need of hospital treatment. Transfer across care levels for this patient group increases the risk of adverse events. The aim of this paper is to establish knowledge of quality in transitional care of the elderly in two Norwegian hospital regions by identifying issues affecting the quality of transitional care and based on these issues suggest improvement measures.Methodology: Included in the study were elderly patients (75+ receiving health care in the municipality admitted to hospital emergency department or discharged to community health care with hip fracture or with a general medical diagnosis. Participant observations of admission and discharge transitions (n = 41 were carried out by two researchers.Results: Six main challenges with belonging descriptions have been identified: (1 next of kin (bridging providers, advocacy, support, information brokering, (2 patient characteristics (level of satisfaction, level of insecurity, complex clinical conditions, (3 health care personnel's competence (professional, system, awareness of others’ roles, (4 information exchange (oral, written, electronic, (5 context (stability, variability, change incentives, number of patient handovers and (6 patient assessment (complex clinical picture, patient description, clinical assessment.Conclusion: Related to the six main challenges, several measures have been suggested to improve quality in transitional care, e.g. information to and involvement of patients and next of kin, staff training, standardisation of routines and inter-organisational staff meetings.

  18. Cross-age mentoring to support A-level pupils’ transition into Higher Education and undergraduate students’ employability

    OpenAIRE

    James, Alana I.

    2014-01-01

    Two challenges identified for psychology higher education are supporting entry students’ transition, and supporting graduates’ transition into employment. The evaluation of the first phase of a cross-age mentoring action research project targeting these issues is presented; eight psychology undergraduates mentored 20 A-level psychology pupils in two schools. Mentors showed significant increases in two of nine psychological literacies, in self-efficacy but not self-esteem, were highly satisfie...

  19. Transition Theory – Sustainable Transition of Socio-Technical Systems

    DEFF Research Database (Denmark)

    Søndergård, Bent; Holm, Jesper; Stauning, Inger

    2015-01-01

    Theories of transition management, transition studies and social practise theory Applied to studies of hosuing and construction......Theories of transition management, transition studies and social practise theory Applied to studies of hosuing and construction...

  20. University and Transitions to Democracy in Mediterranean Europe and Latin America (1970-1980. Presentation

    Directory of Open Access Journals (Sweden)

    Sara González Gómez

    2015-06-01

    Full Text Available Universities and periods of transition to democracy form the tandem analyzed in the monograph the journal Espacio, Tiempo y Educación presented in this issue. A total of eight studies –from Spain, Greece, Portugal, Brazil and Chile– makes up a volume approaching different question (student mobilization, models of university, claims of teachers, regulatory framework... and exploring changes, evolution or inertia experienced in some European and Latin American universities during what Huntington (1990 called the «third wave» of transition to democracy. This outline of studies aims at expanding the information available on the binomial formed by University and democratic transition, a topic rather limited investigated at present, and, above all, encouraging to develop new lines of research focused on a suggestive and critical issue to understand the history of our universities. How to reference this article González Gómez, S. (2015. Universidad y Transiciones a la Democracia en la Europa mediterránea e Iberoamérica (1970-1980. Presentación. Espacio, Tiempo y Educación, 2(2, 25-32. doi: http://dx.doi.org/10.14516/ete.2015.002.002.002

  1. Gravitational waves from a first-order electroweak phase transition: a brief review.

    Science.gov (United States)

    Weir, David J

    2018-03-06

    We review the production of gravitational waves by an electroweak first-order phase transition. The resulting signal is a good candidate for detection at next-generation gravitational wave detectors, such as LISA. Detection of such a source of gravitational waves could yield information about physics beyond the Standard Model that is complementary to that accessible to current and near-future collider experiments. We summarize efforts to simulate and model the phase transition and the resulting production of gravitational waves.This article is part of the Theo Murphy meeting issue 'Higgs cosmology'. © 2018 The Author(s).

  2. New nurse transition: success through aligning multiple identities.

    Science.gov (United States)

    Leong, Yee Mun Jessica; Crossman, Joanna

    2015-01-01

    The purpose of this paper is to explore the perceptions of new nurses in Singapore of their experiences of role transition and to examine the implications for managers in terms of employee training, development and retention. This qualitative study was conducted using a constructivist grounded theory approach. In total 26 novice nurses and five preceptors (n=31) from five different hospitals participated in the study. Data were collected from semi-structured interviews and reflective journal entries and analysed using the constant comparative method. The findings revealed that novice nurses remained emotionally and physically challenged when experiencing role transition. Two major constructs appear to play an important part in the transition process; learning how to Fit in and aligning personal with professional and organisational identities. The findings highlight factors that facilitate or impede Fitting in and aligning these identities. Although the concept of Fitting in and its relation to the attrition of novice nurses has been explored in global studies, that relationship has not yet been theorised as the dynamic alignment of multiple identities. Also, whilst most research around Fitting in, identity and retention has been conducted in western countries, little is known about these issues and their interrelationship in the context of Singapore. The study should inform decision making by healthcare organisations, nurse managers and nursing training institutions with respect to improving the transition experience of novice nurses.

  3. What Effect Does Transition Have on Health and Well-Being in Young People with Intellectual Disabilities? A Systematic Review.

    Science.gov (United States)

    Young-Southward, Genevieve; Philo, Christopher; Cooper, Sally-Ann

    2017-09-01

    Transition to adulthood might be a risk period for poor health in people with intellectual disabilities. However, the present authors could find no synthesis of evidence on health and well-being outcomes during transition in this population. This review aimed to answer this question. PRISMA/MOOSE guidelines were followed. Search terms were defined, electronic searches of six databases were conducted, reference lists and key journals were reviewed, and grey literature was searched. Papers were selected based on clear inclusion criteria. Data were extracted from the selected papers, and their quality was systematically reviewed. The review was prospectively registered on PROSPERO: CRD42015016905. A total of 15 985 articles were extracted; of these, 17 met the inclusion criteria. The results of these articles were mixed but suggested the presence of some health and well-being issues in this population during transition to adulthood, including obesity and sexual health issues. This review reveals a gap in the literature on transition and health and points to the need for future work in this area. © 2016 John Wiley & Sons Ltd.

  4. Transition to motherhood in type 1 diabetes: design of the pregnancy and postnatal well-being in transition questionnaires.

    Science.gov (United States)

    Rasmussen, Bodil; Dunning, Trisha; Hendrieckx, Christel; Botti, Mari; Speight, Jane

    2013-02-27

    Life transitions are associated with high levels of stress affecting health behaviours among people with Type 1 diabetes. Transition to motherhood is a major transition with potential complications accelerated by pregnancy with risks of adverse childbirth outcomes and added anxiety and worries about pregnancy outcomes. Further, preparing and going through pregnancy requires vigilant attention to a diabetes management regimen and detailed planning of everyday activities with added stress on women. Psychological and social well-being during and after pregnancy are integral for good pregnancy outcomes for both mother and baby. The aim of this study is to establish the face and content validity of two novel measures assessing the well-being of women with type 1 diabetes in their transition to motherhood, 1) during pregnancy and 2) during the postnatal period. The approach to the development of the Pregnancy and Postnatal Well-being in T1DM Transition questionnaires was based on a four-stage pre-testing process; systematic overview of literature, items development, piloting testing of questionnaire and refinement of questionnaire. The questionnaire was reviewed at every stage by expert clinicians, researchers and representatives from consumer groups. The cognitive debriefing approach confirmed relevance of issues and identified additional items. The literature review and interviews identified three main areas impacting on the women's postnatal self-management; (1) psychological well-being; (2) social environment, (3) physical (maternal and fetal) well-being. The cognitive debriefing in pilot testing of the questionnaire identified that immediate postnatal period was difficult, particularly when the women were breastfeeding and felt depressed. The questionnaires fill an important gap by systematically assessing the psychosocial needs of women with type 1 diabetes during pregnancy and in the immediate postnatal period. The questionnaires can be used in larger data

  5. Neutrino physics today, important issues and the future

    Energy Technology Data Exchange (ETDEWEB)

    Parke, Stephen J.; /Fermilab

    2010-10-01

    The status and the most important issues in neutrino physics will be summarized as well as how the current, pressing questions will be addressed by future experiments. Since the discovery of neutrino flavor transitions by the SuperKamiokande experiment in 1998, which demonstrates that neutrinos change and hence their clocks tick, i.e. they are not traveling at the speed of light and hence are not massless, the field of neutrino physics has made remarkable progress in untangling the nature of the neutrino. However, there are still many important questions to answer.

  6. Energy transition: 2020-2050, a future to be built, a way forward to be charted

    International Nuclear Information System (INIS)

    Tissot-Colle, Catherine; Jouzel, Jean

    2013-01-01

    A highly topical issue, energy transition has become the only possible response to the challenges posed by climate change, the depletion of easily accessible natural resources and the changes in the demand for energy. The ESEC considers that energy transition must be a response to the climatic, ecological, economic and social challenges which we face. It will require proactive engagement in order to achieve a low-carbon, energy-efficient society, which only a strong political will can create

  7. The German energy transition in 5 popular beliefs - Alternatives Economiques, January 2017, Nr 364 bis

    International Nuclear Information System (INIS)

    Althoff, Jens; Hutinet, Laurent; Belliard, David; Boulanger, Vincent; Ruedinger, Andreas

    2017-01-01

    This publication first discusses and denies five popular beliefs often heard or read in France about the German energy transition: Germany pollutes us with its coal-fired plants, phasing out nuclear is impossible, 100 per cent of renewable energies is an utopia, energy transition slows down the economy, we will never be able to move without oil. The other articles present the example of a German small town where inhabitants took charge of electric power production, outline that the German energy transition comes along an actual democratic revolution through the appropriation of renewable energy production tools, and discuss the difficult issue of phasing out carbon

  8. The 2004 Transit of Venus as a Space Science Education Opportunity

    Science.gov (United States)

    Odenwald, S.; Mayo, L.; Vondrak, R.; Thieman, J.; Hawkins, I.; Schultz, G.

    2003-12-01

    We will present some of the programs and activities that NASA and its missions are preparing in order to support public and K12 education in space science and astronomy using the 2004 transit of Venus as a focal event. The upcoming transit of Venus on June 8 offers a unique opportunity to educate students and the general public about the scale of the solar system and the universe, as well as basic issues in comparative planetology. NASA's Sun-Earth Connection Education Forum is offering a number of programs to take advantage of this rare event. Among these are a live web cast from Spain of the entire transit, a series of radio and TV programs directed at students and the general public, a web cast describing extra-solar planet searches using the transit geometry, and archived observations produced by public observatories and student-operated solar viewers. The NASA/OSS Education Forums will also partner with science museums, planetaria and teachers across the country to bring the transit of Venus 'down to Earth'. In addition to offering enrichment activities in mathematics and space science, we also describe collaborations that have yielded unique historical resources including online archives of newspaper articles from the 1874 and 1882 transits. In addition, in collaboration with the Library of Congress Music Division, we have supported a modern re-orchestration of John Philip Sousa's Transit of Venus March which has not been performed since 1883. We anticipate that the transit of Venus will be a significant event of considerable public interest and curiosity, if the newspaper headlines from the transit seen in 1882 are any indication.

  9. Transition from an asylum seeker–specific health service to mainstream primary care for community-based asylum seekers: a qualitative interview study

    OpenAIRE

    Genevieve L Fair; Mark F Harris; Mitchell M Smith

    2018-01-01

    Background and aim: Transition of asylum seekers from special-purpose health services to mainstream primary care is both necessary and difficult. This study explores the issues encountered by asylum seekers undergoing this transition in Sydney, Australia. Methods: Qualitative semistructured interviews were conducted with nine asylum seeker patients and nine staff working in the sector. Results: Asylum seekers faced significant challenges in the transition to mainstream primary care. C...

  10. The changing structure of the electric power industry: Selected issues, 1998

    International Nuclear Information System (INIS)

    1998-07-01

    More than 3,000 electric utilities in the United States provide electricity to sustain the Nation's economic growth and promote the well-being of its inhabitants. At the end of 1996, the net generating capability of the electric power industry stood at more than 776,000 megawatts. Sales to ultimate consumers in 1996 exceeded 3.1 trillion kilowatthours at a total cost of more than $210 billion. In addition, the industry added over 9 million new customers during the period from 1990 through 1996. The above statistics provide an indication of the size of the electric power industry. Propelled by events of the recent past, the industry is currently in the midst of changing from a vertically integrated and regulated monopoly to a functionally unbundled industry with a competitive market for power generation. Advances in power generation technology, perceived inefficiencies in the industry, large variations in regional electricity prices, and the trend to competitive markets in other regulated industries have all contributed to the transition. Industry changes brought on by this movement are ongoing, and the industry will remain in a transitional state for the next few years or more. During the transition, many issues are being examined, evaluated, and debated. This report focuses on three of them: how wholesale and retail prices have changed since 1990; the power and ability of independent system operators (ISOs) to provide transmission services on a nondiscriminatory basis; and how issues that affect consumer choice, including stranded costs and the determination of retail prices, may be handled either by the US Congress or by State legislatures

  11. The changing structure of the electric power industry: Selected issues, 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    More than 3,000 electric utilities in the United States provide electricity to sustain the Nation`s economic growth and promote the well-being of its inhabitants. At the end of 1996, the net generating capability of the electric power industry stood at more than 776,000 megawatts. Sales to ultimate consumers in 1996 exceeded 3.1 trillion kilowatthours at a total cost of more than $210 billion. In addition, the industry added over 9 million new customers during the period from 1990 through 1996. The above statistics provide an indication of the size of the electric power industry. Propelled by events of the recent past, the industry is currently in the midst of changing from a vertically integrated and regulated monopoly to a functionally unbundled industry with a competitive market for power generation. Advances in power generation technology, perceived inefficiencies in the industry, large variations in regional electricity prices, and the trend to competitive markets in other regulated industries have all contributed to the transition. Industry changes brought on by this movement are ongoing, and the industry will remain in a transitional state for the next few years or more. During the transition, many issues are being examined, evaluated, and debated. This report focuses on three of them: how wholesale and retail prices have changed since 1990; the power and ability of independent system operators (ISOs) to provide transmission services on a nondiscriminatory basis; and how issues that affect consumer choice, including stranded costs and the determination of retail prices, may be handled either by the US Congress or by State legislatures.

  12. Comparative Issues of Cathode Materials for Li-Ion Batteries

    Directory of Open Access Journals (Sweden)

    Christian M. Julien

    2014-03-01

    Full Text Available After an introduction to lithium insertion compounds and the principles of Li-ion cells, we present a comparative study of the physical and electrochemical properties of positive electrodes used in lithium-ion batteries (LIBs. Electrode materials include three different classes of lattices according to the dimensionality of the Li+ ion motion in them: olivine, layered transition-metal oxides and spinel frameworks. Their advantages and disadvantages are compared with emphasis on synthesis difficulties, electrochemical stability, faradaic performance and security issues.

  13. Edge Delamination of Monolayer Transition Metal Dichalcogenides.

    Science.gov (United States)

    Ly, Thuc Hue; Yun, Seok Joon; Thi, Quoc Huy; Zhao, Jiong

    2017-07-25

    Delamination of thin films from the supportive substrates is a critical issue within the thin film industry. The emergent two-dimensional, atomic layered materials, including transition metal dichalcogenides, are highly flexible; thus buckles and wrinkles can be easily generated and play vital roles in the corresponding physical properties. Here we introduce one kind of patterned buckling behavior caused by the delamination from a substrate initiated at the edges of the chemical vapor deposition synthesized monolayer transition metal dichalcogenides, led by thermal expansion mismatch. The atomic force microscopy and optical characterizations clearly showed the puckered structures associated with the strain, whereas the transmission electron microscopy revealed the special sawtooth-shaped edges, which break the geometrical symmetry for the buckling behavior of hexagonal samples. The condition of the edge delamination is in accordance with the fracture behavior of thin film interfaces. This edge delamination and buckling process is universal for most ultrathin two-dimensional materials, which requires more attention in various future applications.

  14. Transitions between superstatistical regimes: Validity, breakdown and applications

    Science.gov (United States)

    Jizba, Petr; Korbel, Jan; Lavička, Hynek; Prokš, Martin; Svoboda, Václav; Beck, Christian

    2018-03-01

    Superstatistics is a widely employed tool of non-equilibrium statistical physics which plays an important rôle in analysis of hierarchical complex dynamical systems. Yet, its "canonical" formulation in terms of a single nuisance parameter is often too restrictive when applied to complex empirical data. Here we show that a multi-scale generalization of the superstatistics paradigm is more versatile, allowing to address such pertinent issues as transmutation of statistics or inter-scale stochastic behavior. To put some flesh on the bare bones, we provide a numerical evidence for a transition between two superstatistics regimes, by analyzing high-frequency (minute-tick) data for share-price returns of seven selected companies. Salient issues, such as breakdown of superstatistics in fractional diffusion processes or connection with Brownian subordination are also briefly discussed.

  15. The Tax Base in Transition: The Case of Bulgaria, World Bank Policy Research Working Paper Series No. 1267 (March 1994), The World Bank.

    OpenAIRE

    Zeljko Bogetic; Arye Hillman

    2005-01-01

    Meeting government revenue needs without inhibiting private sector development is a key challenge of tax policy during the transition from the socialist system. The paper explores issues in the design of tax bases and tax structures in the transition and argues that transition economies would need to adopt a lower and simpler tax structure than the ones prevailing in developed Western market economies.

  16. Automated driving and its effects on the safety ecosystem: How do compatibility issues affect the transition period?

    NARCIS (Netherlands)

    van Loon, R.J.; Martens, Marieke Hendrikje

    2015-01-01

    Different components of automated vehicles are being made available commercially as we speak. Much research has been conducted into these components and many of these have been studied with respect to their effects on safety, but the transition period from non-automated driving to fully automated

  17. Automated driving and its effect on the safety ecosystem: how do compatibility issues affect the transition period?

    NARCIS (Netherlands)

    Loon, R.J. van; Martens, M.H.

    2015-01-01

    Different components of automated vehicles are being made available commercially as we speak. Much research has been conducted into these components and many of these have been studied with respect to their effects on safety, but the transition period from non-automated driving to fully automated

  18. Identifying blocks to boost industrial development indispensable to energy transition

    International Nuclear Information System (INIS)

    2012-11-01

    For different sectors (biomass energy, fossil and geothermal energies, nuclear energies, solar energy, marine, hydraulic and wind energies, energies in transports, construction, industries and agriculture, prospective and education, grids and storage), this report gives a brief overview of the present status and problematic, and briefly presents the main issues to be solved to develop these sectors within the perspective of energy transition and sustainable development

  19. Ethical and methodological issues in research with Sami experiencing disability.

    Science.gov (United States)

    Melbøe, Line; Hansen, Ketil Lenert; Johnsen, Bjørn-Eirik; Fedreheim, Gunn Elin; Dinesen, Tone; Minde, Gunn-Tove; Rustad, Marit

    2016-01-01

    A study of disability among the indigenous Sami people in Norway presented a number of ethical and methodological challenges rarely addressed in the literature. The main study was designed to examine and understand the everyday life, transitions between life stages and democratic participation of Norwegian Sami people experiencing disability. Hence, the purpose of this article is to increase the understanding of possible ethical and methodological issues in research within this field. The article describes and discusses ethical and methodological issues that arose when conducting our study and identifies some strategies for addressing issues like these. The ethical and methodological issues addressed in the article are based on a qualitative study among indigenous Norwegian Sami people experiencing disability. The data in this study were collected through 31 semi-structured in-depth interviews with altogether 24 Sami people experiencing disability and 13 next of kin of Sami people experiencing disability (8 mothers, 2 fathers, 2 sister and 1 guardian). The researchers identified 4 main areas of ethical and methodological issues. We present these issues chronologically as they emerged in the research process: 1) concept of knowledge when designing the study, 2) gaining access, 3) data collection and 4) analysis and accountability. The knowledge generated from this study has the potential to benefit future health research, specifically of Norwegian Sami people experiencing disability, as well as health research concerning indigenous people in general, providing scientific-based insight into important ethical and methodological issues in research with indigenous people experiencing disability.

  20. Transition from High School to Associate Degree Nursing Education: A Qualitative Study

    Science.gov (United States)

    Mitchell, Kathy Jessee

    2012-01-01

    Nursing is facing a critical shortage and retention of nursing students is of paramount importance. Much research has been completed related to retention in nursing education and student success, but there is very little in current literature related to issues associated with the transition from high school to associate degree nursing (ADN)…

  1. Institutional Interfaces and Actors’ Behavior in Transitional Real Estate Markets of Addis Ababa (Ethiopia)

    NARCIS (Netherlands)

    F.M. Truneh (Frew)

    2013-01-01

    markdownabstract__Abstract__ With the collapse of communism in the early 1990s which heralded the transition from centrally planned economy to free market economy, the issues of property rights and the role of institutions in development have become of paramount importance. However, compared

  2. Modeling boundary-layer transition in DNS and LES using Parabolized Stability Equations

    Science.gov (United States)

    Lozano-Duran, Adrian; Hack, M. J. Philipp; Moin, Parviz

    2016-11-01

    The modeling of the laminar region and the prediction of the point of transition remain key challenges in the numerical simulation of boundary layers. The issue is of particular relevance for wall-modeled large eddy simulations which require 10 to 100 times higher grid resolution in the thin laminar region than in the turbulent regime. Our study examines the potential of the nonlinear parabolized stability equations (PSE) to provide an accurate, yet computationally efficient treatment of the growth of disturbances in the pre-transitional flow regime. The PSE captures the nonlinear interactions that eventually induce breakdown to turbulence, and can as such identify the onset of transition without relying on empirical correlations. Since the local PSE solution at the point of transition is the solution of the Navier-Stokes equations, it provides a natural inflow condition for large eddy and direct simulations by avoiding unphysical transients. We show that in a classical H-type transition scenario, a combined PSE/DNS approach can reproduce the skin-friction distribution obtained in reference direct numerical simulations. The computational cost in the laminar region is reduced by several orders of magnitude. Funded by the Air Force Office of Scientific Research.

  3. About energy transition. Questions and current debate. Les Cahiers de Global Chance No 35/36 - June/November 2014

    International Nuclear Information System (INIS)

    Colombier, Michel; Chancel, Lucas; Bullier, Adrien; Milin, Christophe; Ruedinger, Andreas; Chappoz, Loic; Dessus, Benjamin; Laponche, Bernard; Hermitte, M-A.; Jedliczka, Marc

    2014-06-01

    A first set of articles addresses and comments the issue of energy transition: transition in progress; alternate financing arrangements for building energetic renovation; the French debate on energy poverty in the light of European examples; how to learn from the present for a better preparation of the future for the European electricity market in front of energy transition; a focus on New-York State as an example of energy transition in progress in the USA. The second set of articles addresses nuclear issues: the citizen conference of the management of nuclear wastes within the Cigeo project; a critical discussion of the reaction of the ANDRA to this conference; the costs of life extension of nuclear reactors (comparison of investments according to different strategies - continuation, fleet reduction, phasing out nuclear, and assessment of the associated MWh economic costs). The third set of articles proposes a focus on methane: discussion of radiative forcing and Warming Global Potential of methane as they are mentioned and discussed in IPCC reports; evolution of methane emissions in Europe by different sectors, and challenges and costs of a programme of emission reduction in the different economic sectors

  4. Strategic Plan for Coordinating Rural Intelligent Transportation System (ITS) Transit Development in the Great Smoky Mountains National Park

    Energy Technology Data Exchange (ETDEWEB)

    Truett, L.F.

    2002-12-19

    The Great Smoky Mountains National Park, located along the border between North Carolina and Tennessee, is the most visited national park in the United States. This rugged, mountainous area presents many transportation challenges. The immense popularity of the Smokies and the fact that the primary mode of transportation within the park is the personal vehicle have resulted in congestion, damage to the environment, impacts on safety, and a degraded visitor experience. Access to some of the Smokies historical, cultural, and recreational attractions via a mass transit system could alleviate many of the transportation issues. Although quite a few organizations are proponents of a mass transit system for the Smokies, there is a lack of coordination among all parties. In addition, many local residents are not completely comfortable with the idea of transit in the Smokies. This document provides a brief overview of the current transportation needs and limitations in the Great Smoky Mountains National Park, identifies agencies and groups with particular interests in the Smokies, and offers insights into the benefits of using Intelligent Transportation Systems (ITS) technologies in the Smokies. Recommendations for the use of rural ITS transit to solve two major transportation issues are presented.

  5. Mode transition coordinated control for a compound power-split hybrid car

    Science.gov (United States)

    Wang, Chen; Zhao, Zhiguo; Zhang, Tong; Li, Mengna

    2017-03-01

    With a compound power-split transmission directly connected to the engine in hybrid cars, dramatic fluctuations in engine output torque result in noticeable jerks when the car is in mode transition from electric drive mode to hybrid drive mode. This study designed a mode transition coordinated control strategy, and verified that strategy's effectiveness with both simulations and experiments. Firstly, the mode transition process was analyzed, and ride comfort issues during the mode transition process were demonstrated. Secondly, engine ripple torque was modeled using the measured cylinder pumping pressure when the engine was not in operation. The complete dynamic plant model of the power-split hybrid car was deduced, and its effectiveness was validated by a comparison of experimental and simulation results. Thirdly, a coordinated control strategy was designed to determine the desired engine torque, motor torque, and the moment of fuel injection. Active damping control with two degrees of freedom, based on reference output shaft speed estimation, was designed to mitigate driveline speed oscillations. Carrier torque estimation based on transmission kinematics and dynamics was used to suppress torque disturbance during engine cranking. The simulation and experimental results indicate that the proposed strategy effectively suppressed vehicle jerks and improved ride comfort during mode transition.

  6. "School Doesn't Feel as Much of a Partnership": Parents' Perceptions of Their Children's Transition from Nursery School to Reception Class

    Science.gov (United States)

    Shields, Polly

    2009-01-01

    This small-scale study explores a group of English parents' perceptions of their relationships with their child's nursery school and, after the transition to Reception class, their primary school. It references current research and literature on the issues of transition and the role of parents in their children's education. Findings from…

  7. Age-Based Differences in Care Setting Transitions over the Last Year of Life

    Directory of Open Access Journals (Sweden)

    Donna M. Wilson

    2011-01-01

    Full Text Available Context. Little is known about the number and types of moves made in the last year of life to obtain healthcare and end-of-life support, with older adults more vulnerable to care setting transition issues. Research Objective. Compare care setting transitions across older (65+ years and younger individuals. Design. Secondary analyses of provincial hospital and ambulatory database data. Every individual who lived in the province for one year prior to death from April 1, 2005 through March 31, 2007 was retained (N=19,397. Results. Transitions averaged 3.5, with 3.9 and 3.4 for younger and older persons, respectively. Older persons also had fewer ER and ambulatory visits, fewer procedures performed in the last year of life, but longer inpatient stays (42.7 days versus 36.2 for younger persons. Conclusion. Younger and older persons differ somewhat in the number and type of end-of-life care setting transitions, a matter for continuing research and healthcare policy.

  8. Theoretical issues in Spheromak research

    International Nuclear Information System (INIS)

    Cohen, R. H.; Hooper, E.B.; LoDestro, L.L.; Mattor, N.; Pearlstein, L.D.; Ryutov, D.D.

    1997-01-01

    This report summarizes the state of theoretical knowledge of several physics issues important to the spheromak. It was prepared as part of the preparation for the Sustained Spheromak Physics Experiment (SSPX), which addresses these goals: energy confinement and the physics which determines it; the physics of transition from a short-pulsed experiment, in which the equilibrium and stability are determined by a conducting wall (''''flux conserver'''') to one in which the equilibrium is supported by external coils. Physics is examined in this report in four important areas. The status of present theoretical understanding is reviewed, physics which needs to be addressed more fully is identified, and tools which are available or require more development are described. Specifically, the topics include: MHD equilibrium and design, review of MHD stability, spheromak dynamo, and edge plasma in spheromaks

  9. Information report by the Commission of European Affairs making observations on the bill project nr 2188 related to energy transition for a green growth - Nr 2199

    International Nuclear Information System (INIS)

    Auroi, Danielle

    2014-01-01

    After a synthesis which addresses and discusses the climate context and challenge, the importance and complexity of the energy issue within this context, the European commitment on these issues (energy efficiency, energy saving, greenhouse gas emissions), and the content and objectives of the French bill project on energy transition, this report outlines the need of an as quick as possible implementation of energy transition to cope with the climate emergency, and that new international constraints are also advocating for a transition towards a new energy model. It shows that the French bill project fully forms part of the European approach, and proposes additional measures

  10. Reforms and Economic Growth in Transition Economies: Complementarity, Sequencing and Speed

    Directory of Open Access Journals (Sweden)

    Karsten Staehr

    2005-12-01

    Full Text Available This paper considers the effects of sequencing and reform speed on output performance in transition countries. These largely unsettled issues are addressed using principal component techniques to construct reform clusters and by explicit tests of speed effects. The results indicate that broad-based reforms are good for output growth, but so is a policy of liberalisation and small-scale privatisation without structural reforms. Conversely, large-scale privatisation without adjoining reforms, market opening without supporting reforms and bank liberalisation without enterprise restructuring affect growth negatively. Swift reform policies allow transition countries to benefit from higher growth for longer time. The speed of reforms appears otherwise to have little effect on growth in the short and medium term.

  11. ERDF at the heart of the debate on energy transition in Brittany

    International Nuclear Information System (INIS)

    Corolleur, Antoine; Le Menn, Alain; Lucas, Jean

    2013-06-01

    ERDF (Electricite Reseau Distribution France - now Enedis), one of the French power distribution utilities, is particularly concerned by the French energy transition policy towards a sustainable development and a 'green growth'. Its main issues, as seen with the example of the Brittany region, are to be able to better integrate the various renewable energies (some of them - wind and solar power - being intermittent and not programmable) into the national electric power network, to better manage the power peak by developing and modernizing the network, and to guarantee the public service missions of power distribution for all and on the whole territory. Various aspects are addressed, such as the industrial and economical stakes, the issue of power storage, the development strategy for electric vehicles, for energy conservation and energy efficiency policies, for renewable energy sources (notably sea- and agriculture-related energies in Brittany), costs and financing levers for the energy transition policy, the electric power pricing regulations, the integration of renewable electric power into the grid, etc

  12. Toward an Understanding of People Management Issues in SMEs: a South-Eastern European Perspective

    Science.gov (United States)

    Szamosi, Leslie T.; Duxbury, Linda; Higgins, Chris

    2004-01-01

    The focus of this paper is on developing an understanding, and benchmarking, human resource management HRM issues in small and medium enterprises SMEs in South-Eastern Europe. The importance of SMEs in helping transition-based economies develop is critical, but at the same time the research indicates that the movement toward westernized business…

  13. Supporting Youth Transitioning out of Foster Care. Issue Brief 1: Education Programs. OPRE Report No. 2014-66

    Science.gov (United States)

    Dworsky, Amy; Smithgall, Cheryl; Courtney, Mark E.

    2014-01-01

    Youth transitioning out of foster care and into adulthood need many supports to navigate the challenges they face. Over the past three decades, federal child welfare policy has significantly increased the availability of those supports. In 1999, the Foster Care Independence Act amended Title IV-E of the Social Security Act to create the Chafee…

  14. Transitions to sustainable development. On the relevance of exploiting market forces

    International Nuclear Information System (INIS)

    Glasbergen, P.

    2002-01-01

    Transition management is a new concept in Dutch environmental policy and management. Bringing about transitions in society is a classical issue in planning and policy theory. One of the main debates is on the relationship between market and plan as coordinating mechanisms in society. Based on an examination of this debate, this article argues that there is no contradiction between incremental change and structural changes in society. In terms of these incremental changes, it observes a process of sustainable development that has gone on for years. In the author's view, the key to sustainable development is to be found in private investments. Transitions in a liberal democratic society necessarily take place via the market mechanism and come about as societal learning processes. The main challenge is to develop structures in which private capital is applied to achieve long-term processes of societal change. The FairTrade market and the clean development mechanism are discussed by way of examples [nl

  15. Phase Transition Control for High-Performance Blade-Coated Perovskite Solar Cells

    KAUST Repository

    Li, Jianbo

    2018-05-07

    Summary Here, we have identified that the key issue for rational transitioning from spin-coating to blade-coating processes of perovskite films arises from whether intermediate phases participate in the phase transition. In situ characterizations were carried out to provide a comprehensive picture of structural evolution and crystal growth mechanisms. These findings present opportunities for designing an effective process for blade-coating perovskite film: a large-grained dense perovskite film with high crystal quality and photophysical properties can be obtained only via direct crystallization for both spin-coating and blade-coating processes. As a result, the blade-coated MAPbI3 films deliver excellent charge-collection efficiency at both short circuit and open circuit, and photovoltaic properties with efficiencies of 18.74% (0.09 cm2) and 17.06% (1 cm2) in planar solar cells. The significant advances in understanding how the phase transition links spin-coating and blade-coating processes should provide a path toward high-performance printed perovskite devices.

  16. Incumbent Decisions about Succession Transitions in Family Firms: A Conceptual Model

    Directory of Open Access Journals (Sweden)

    Britta Boyd

    2014-11-01

    Full Text Available In the family business literature, succession research has focused on the family member as they enter the leadership role or on the different issues that affect the succession process. Although researchers have acknowledged that succession in family businesses is “punctuated” by decision making events, less attention has been given to understanding how incumbents make decisions about ownership and management transitions. In an effort to continue to understand the succession process it is important to understand how incumbents make decisions about the type of transitions they intend to engage in (i.e., intra-family succession, out of family succession, or no succession. Building on the theory of planned behavior and the socioemotional wealth framework (SEW, this manuscript presents a conceptual framework to understand the factors that influence succession transitions and the role that contextual factors can play in this decision-making process. We present theory driven propositions and discuss the implications for understanding and evaluation of the succession process.

  17. Phase transitions in single macromolecules: Loop-stretch transition versus loop adsorption transition in end-grafted polymer chains

    Science.gov (United States)

    Zhang, Shuangshuang; Qi, Shuanhu; Klushin, Leonid I.; Skvortsov, Alexander M.; Yan, Dadong; Schmid, Friederike

    2018-01-01

    We use Brownian dynamics simulations and analytical theory to compare two prominent types of single molecule transitions. One is the adsorption transition of a loop (a chain with two ends bound to an attractive substrate) driven by an attraction parameter ɛ and the other is the loop-stretch transition in a chain with one end attached to a repulsive substrate, driven by an external end-force F applied to the free end. Specifically, we compare the behavior of the respective order parameters of the transitions, i.e., the mean number of surface contacts in the case of the adsorption transition and the mean position of the chain end in the case of the loop-stretch transition. Close to the transition points, both the static behavior and the dynamic behavior of chains with different length N are very well described by a scaling ansatz with the scaling parameters (ɛ - ɛ*)Nϕ (adsorption transition) and (F - F*)Nν (loop-stretch transition), respectively, where ϕ is the crossover exponent of the adsorption transition and ν is the Flory exponent. We show that both the loop-stretch and the loop adsorption transitions provide an exceptional opportunity to construct explicit analytical expressions for the crossover functions which perfectly describe all simulation results on static properties in the finite-size scaling regime. Explicit crossover functions are based on the ansatz for the analytical form of the order parameter distributions at the respective transition points. In contrast to the close similarity in equilibrium static behavior, the dynamic relaxation at the two transitions shows qualitative differences, especially in the strongly ordered regimes. This is attributed to the fact that the surface contact dynamics in a strongly adsorbed chain is governed by local processes, whereas the end height relaxation of a strongly stretched chain involves the full spectrum of Rouse modes.

  18. Zebra finches can use positional and transitional cues to distinguish vocal element strings.

    Science.gov (United States)

    Chen, Jiani; Ten Cate, Carel

    2015-08-01

    Learning sequences is of great importance to humans and non-human animals. Many motor and mental actions, such as singing in birds and speech processing in humans, rely on sequential learning. At least two mechanisms are considered to be involved in such learning. The chaining theory proposes that learning of sequences relies on memorizing the transitions between adjacent items, while the positional theory suggests that learners encode the items according to their ordinal position in the sequence. Positional learning is assumed to dominate sequential learning. However, human infants exposed to a string of speech sounds can learn transitional (chaining) cues. So far, it is not clear whether birds, an increasingly important model for examining vocal processing, can do this. In this study we use a Go-Nogo design to examine whether zebra finches can use transitional cues to distinguish artificially constructed strings of song elements. Zebra finches were trained with sequences differing in transitional and positional information and next tested with novel strings sharing positional and transitional similarities with the training strings. The results show that they can attend to both transitional and positional cues and that their sequential coding strategies can be biased toward transitional cues depending on the learning context. This article is part of a Special Issue entitled: In Honor of Jerry Hogan. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Quantum phase transitions

    International Nuclear Information System (INIS)

    Sachdev, S.

    1999-01-01

    Phase transitions are normally associated with changes of temperature but a new type of transition - caused by quantum fluctuations near absolute zero - is possible, and can tell us more about the properties of a wide range of systems in condensed-matter physics. Nature abounds with phase transitions. The boiling and freezing of water are everyday examples of phase transitions, as are more exotic processes such as superconductivity and superfluidity. The universe itself is thought to have passed through several phase transitions as the high-temperature plasma formed by the big bang cooled to form the world as we know it today. Phase transitions are traditionally classified as first or second order. In first-order transitions the two phases co-exist at the transition temperature - e.g. ice and water at 0 deg., or water and steam at 100 deg. In second-order transitions the two phases do not co-exist. In the last decade, attention has focused on phase transitions that are qualitatively different from the examples noted above: these are quantum phase transitions and they occur only at the absolute zero of temperature. The transition takes place at the ''quantum critical'' value of some other parameter such as pressure, composition or magnetic field strength. A quantum phase transition takes place when co-operative ordering of the system disappears, but this loss of order is driven solely by the quantum fluctuations demanded by Heisenberg's uncertainty principle. The physical properties of these quantum fluctuations are quite distinct from those of the thermal fluctuations responsible for traditional, finite-temperature phase transitions. In particular, the quantum system is described by a complex-valued wavefunction, and the dynamics of its phase near the quantum critical point requires novel theories that have no analogue in the traditional framework of phase transitions. In this article the author describes the history of quantum phase transitions. (UK)

  20. An investigation of transitional management problems for the NSTS at NASA

    Science.gov (United States)

    Hunsucker, John

    1988-01-01

    This quarterly report summarizes the ideas and concepts developed by the University of Houston team with the collaboration and support of the Management Integration Offices of NASA. In addition it is hoped that this report will help to stimulate the healthy problem solving process already present at NASA. This is the second report in the fourth year of the research contract. The main aim of the work is to assist the National Space Transportation System (NSTS) in finding ways and means of moving into a truly operational era in the sense of routine timely production of flights. The reader who seeks an understanding of the concepts presented is encouraged to read the reports of the last three years. The overall strategy of this effort is to: (1) search the literature for applications of transition management and other related issues, (2) conduct investigations into the experiences of the industries with the transition management, and (3) to adapt the information found in (1) and (2) above into a form useful to NASA while at the same time applying industrial engineering and engineering management expertise to problems and issues as they emerge.

  1. Palliative patients’ and significant others’ experiences of transitions concerning organizational, psychosocial and existential issues during the course of incurable cancer: A systematic review protocol

    DEFF Research Database (Denmark)

    Madsen, Rikke; Uhrenfeldt, Lisbeth

    2014-01-01

    ABSTRACT Review question/objective The objective of this review is to identify, appraise and synthesize the best available evidence exploring palliative patients’ or their significant others’ experiences of transitions during the course of incurable cancer. In this review, transitions are concept...... exploring euthanasia will be excluded because euthanasia is not included in the WHO definition of palliation. KEYWORDS Lived experience; incurable cancer; patient; significant other; transition; organizational; psychosocial; existential...

  2. Health and wellbeing during transition to adulthood for young people with intellectual disabilities: A qualitative study.

    Science.gov (United States)

    Young-Southward, Genevieve; Cooper, Sally-Ann; Philo, Christopher

    2017-11-01

    Transition to adulthood may have negative consequences for health and wellbeing in individuals with intellectual disabilities (ID), but this aspect of transition has received little investigation. This qualitative study aimed to explore the transition experiences of individuals with ID from their own perspectives, and from that of their parents, in order to identify health or wellbeing implications of transition. Semi-structured interviews were conducted with 17 young people with mild, moderate and severe ID aged 16-27 years and with 23 parents of young people with mild, moderate, severe and profound ID aged 16-26 years. Interviews were analysed using thematic analysis, deploying both emic and etic coding categories. This study provides direct insights into the issues on health and wellbeing that young people with ID and their parents find important during transition. The primary health implication of transition centred on mental health and wellbeing; young people experienced heightened anxiety during transition, and themes identified as contributing to anxiety included: a lack of meaningful activity following school exit; inadequate support during transition; and difficulties associated with 'growing up'. Problem behaviours and obesity were also implicated. The transition from school needs to be better supported in order to ease anxiety for young people during this difficult period. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Is the issue of energy transition correctly posed in present debates?

    International Nuclear Information System (INIS)

    Candel, Sebastien; Brechet, Yves; Brezin, Edouard; Fontecave, Marc; Andre, Jean-Claude; Balian, Roger; Balibar, Sebastien; Bamberger, Yves; Cesarsky, Catherine; Courtillot, Vincent; Duplessy, Jean-Claude; Encrenaz, Pierre; Guillaumont, Robert; Joliot, Pierre; Laval, Guy; Pironneau, Olivier; Pouchard, Michel; Rebut, Paul-Henri; Roux, Didier; Tarascon, Jean-Marie

    2017-01-01

    As it is commonly stated that it would be possible to massively developed renewable energies in order to de-carbonate our energy system by getting rid of fossil and nuclear energies, the authors recall and discuss some facts. They outline that the solution depend on geographical and climatic constraints which are proper to each country, that renewable energies only represents about a quarter of our consumption and raise the problem of intermittency. Moreover, the present status of energy storage technology does not provide a viable and possible solution, and is still to be further developed. They also outline problems faced in Germany where coal fired plants had to be created to solve issues of electricity availability. They outline that France is one of the less carbon-emitting country, due to the importance of nuclear energy. Thus, they outline that realistic scenarios must be proposed in which nuclear will still have its role in a de-carbonated system, and with investments in basic, technological and industrial research on various fields (nuclear wastes and safety, energy storage, CO 2 capture and sequestration)

  4. JGR special issue on Deep Earthquakes

    Science.gov (United States)

    The editor and associate editors of the Journal of Geophysical Research—Solid Earth and Planets invite the submission of manuscripts for a special issue on the topic “Deep- and Intermediate-Focus Earthquakes, Phase Transitions, and the Mechanics of Deep Subduction.”Manuscripts should be submitted to JGR Editor Gerald Schubert (Department of Earth and Space Sciences, University of California, Los Angeles, Los Angeles, CA 90024) before July 1, 1986, in accordance with the usual rules for manuscript submission. Submitted papers will undergo the normal JGR review procedure. For more information, contact either Schubert or the special guest associate editor, Cliff Frohlich (Institute for Geophysics, University of Texas at Austin, 4920 North IH-35, Austin, TX 78751; telephone: 512-451-6223).

  5. Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines

    Science.gov (United States)

    Hirasawa, Kazuhiro; Moriya, Shota; Miyahara, Kana; Kazama, Hiromi; Hirota, Ayako; Takemura, Jun; Abe, Akihisa; Inazu, Masato; Hiramoto, Masaki; Tsukahara, Kiyoaki

    2016-01-01

    Autophagy, a self-digestive system for cytoplasmic components, is required to maintain the amino acid pool for cellular homeostasis. We previously reported that the macrolide antibiotics azithromycin (AZM) and clarithromycin (CAM) have an inhibitory effect on autophagy flux, and they potently enhance the cytocidal effect of various anticancer reagents in vitro. This suggests that macrolide antibiotics can be used as an adjuvant for cancer chemotherapy. Since cancer cells require a larger metabolic demand than normal cells because of their exuberant growth, upregulated autophagy in tumor cells has now become the target for cancer therapy. In the present study, we examined whether macrolides exhibit cytotoxic effect under an amino acid-starving condition in head and neck squamous cancer cell lines such as CAL 27 and Detroit 562 as models of solid tumors with an upregulated autophagy in the central region owing to hypovascularity. AZM and CAM induced cell death under the amino acid-depleted (AAD) culture condition in these cell lines along with CHOP upregulation, although they showed no cytotoxicity under the complete culture medium. CHOP knockdown by siRNA in the CAL 27 cells significantly suppressed macrolide-induced cell death under the AAD culture condition. CHOP-/- murine embryonic fibroblast (MEF) cell lines also attenuated AZM-induced cell death compared with CHOP+/+ MEF cell lines. Using a tet-off atg5 MEF cell line, knockout of atg5, an essential gene for autophagy, also induced cell death and CHOP in the AAD culture medium but not in the complete culture medium. This suggest that macrolide-induced cell death via CHOP induction is dependent on autophagy inhibition. The cytotoxicity of macrolide with CHOP induction was completely cancelled by the addition of amino acids in the culture medium, indicating that the cytotoxicity is due to the insufficient amino acid pool. These data suggest the possibility of using macrolides for “tumor-starving therapy”. PMID

  6. The Dilemma: Career Transition of African American Male Football Players at Division I Institutions

    Science.gov (United States)

    Northcutt, Kellen Jamil

    2013-01-01

    The purpose of this qualitative phenomenological study was to explore and understand perceptions of African American male football athletes at Division I institutions that also played professional football, regarding their collegiate experiences and transition from athletics to post-playing careers. The study examined issues of race and social…

  7. Student paramedic experience of transition into the workforce: A scoping review.

    Science.gov (United States)

    Kennedy, Sean; Kenny, Amanda; O'Meara, Peter

    2015-10-01

    In this article we present the findings from a scoping review that sought to identify what is known about the experiences of paramedic students transitioning into the workforce. Within the emergency healthcare sector, paramedics are primarily tasked with the assessment, treatment and safe transport of patients to hospital. New paramedics entering the workforce are exposed to the full extent of human emotion, injury and suffering as part of their everyday work. There is evidence from other healthcare disciplines that the transition to practice period can be difficult for new graduates. We utilised Arksey and O'Malley's five-stage scoping review framework to identify what is known about the transition of paramedicine graduates to the workplace. The framework involves identifying relevant studies; study selection; charting the data; and collating, summarizing and reporting results. We identified eleven articles that explored transition of newly qualified paramedics. Thematic content was identified and discussed into four separate categories. Each theme revealing the emotional, physical and social impacts new paramedics face as they strive to find acceptance in a new workplace and culture. Given the significant role that paramedics have in modern healthcare, the transition from student to practitioner is a period of significant stress to the new paramedic. Limited research in this field though inhibits a thorough understanding of these issues. Copyright © 2015. Published by Elsevier Ltd.

  8. The transition of young adults with lifelong urological needs from pediatric to adult services: An international children's continence society position statement.

    Science.gov (United States)

    Bower, Wendy F; Christie, Deborah; DeGennaro, Mario; Latthe, Pallavi; Raes, Ann; Romao, Rodrigo L P; Taghizadeh, Arash; Wood, Dan; Woodhouse, Christopher R J; Bauer, Stuart B

    2017-03-01

    Children with urinary tract disorders managed by teams, or individual pediatricians, urologists, nephrologists, gastroenterologists, neurologists, psychologists, and nurses at some point move from child-centered to adult-centered health systems. The actual physical change is referred to as the transfer whilst the process preceding this move constitutes transition of care. Our aims are twofold: to identify management and health-service problems related to children with congenital or acquired urological conditions who advance into adulthood and the clinical implications this has for long-term health and specialist care; and, to understand the issues facing both pediatric and adult-care clinicians and to develop a systems-approach model that meets the needs of young adults, their families and the clinicians working within adult services. Information was gleaned from presentations at an International Children's Continence Society meeting with collaboration from the International Continence Society, that discussed problems of transfer and transitioning such children. Several specialists attending this conference finalized this document identifying issues and highlighting ways to ease this transition and transfer of care for both patients and practitioners. The consensus was, urological patients with congenital or other lifelong care needs, are now entering adulthood in larger numbers than previously, necessitating new planning processes for tailored transfer of management. Adult teams must become familiar with new clinical problems in multiple organ systems and anticipate issues provoked by adolescence and physical growth. During this period of transitional care the clinician or team assists young patients to build attitudes, skills and understanding of processes needed to maximize function of their urinary tract-thus taking responsibility for their own healthcare needs. Preparation must also address, negotiating adult health care systems, psychosocial, educational or

  9. From Caspian to Turkey: The Southern European Gas Corridor's Issues

    International Nuclear Information System (INIS)

    Rebiere, Noemie

    2014-01-01

    With the growth of global energy demand and the raise of conflicts for the control of energy resources and supply routes, energy security is becoming a major issue for the European Union, but also for suppliers and transit countries. The recent crisis in Ukraine highlights the role of gas as a strategic weapon in the Russian external policy and reinforces the need of the European countries to diversify energy sources and supply routes. The southern European gas corridor, which carries hydrocarbons of the Caspian region to Europe through Turkey, is as a key project of E.U. and U.S. strategy to ensure the energy security of Europe. However, with the current instability in the Middle East and the difficulty to set-up an agreement in the Iranian nuclear negotiations, the issue of the ability of the southern gas corridor to be supplied with enough amount of resources remains hypothetical. In this respect, this approach analyses the deep interactions between energy issues, territorial security, political aims and economic interests

  10. Quantum field theory and phase transitions: universality and renormalization group; Theorie quantique des champs et transitions de phase: universalite et groupe de renormalisation

    Energy Technology Data Exchange (ETDEWEB)

    Zinn-Justin, J

    2003-08-01

    In the quantum field theory the problem of infinite values has been solved empirically through a method called renormalization, this method is satisfying only in the framework of renormalization group. It is in the domain of statistical physics and continuous phase transitions that these issues are the easiest to discuss. Within the framework of a course in theoretical physics the author introduces the notions of continuous limits and universality in stochastic systems operating with a high number of freedom degrees. It is shown that quasi-Gaussian and mean field approximation are unable to describe phase transitions in a satisfying manner. A new concept is required: it is the notion of renormalization group whose fixed points allow us to understand universality beyond mean field. The renormalization group implies the idea that long distance correlations near the transition temperature might be described by a statistical field theory that is a quantum field in imaginary time. Various forms of renormalization group equations are presented and solved in particular boundary limits, namely for fields with high numbers of components near the dimensions 4 and 2. The particular case of exact renormalization group is also introduced. (A.C.)

  11. Enhancing STEM Education during School Transition: Bridging the Gap in Science Manipulative Skills

    Science.gov (United States)

    Fadzil, Hidayah Mohd; Saat, Rohaida Mohd

    2014-01-01

    The lack of exposure to practical work in primary schools leads to incompetency in manipulative skills and students may carry this problem with them to secondary school. To address this issues, an in-depth qualitative study was conducted during transition from primary to secondary school. The research involved 10 primary school students (grade 6)…

  12. Transition of Youth with Disabilities to Postsecondary Education. DADD Prism Series. Volume 5

    Science.gov (United States)

    Stodden, Robert, Ed.; Zucker, Stanley, Ed.

    2004-01-01

    This volume presents an organized collection of peer-reviewed articles focused upon issues faced by young persons with intellectual disabilities and those who support them as they prepare for and transition to postsecondary education and other life-long learning activities. The reader is provided with an overview of this field of work, a range of…

  13. Hypocritical transitions? The challenge of urban sustainable mobility transition

    DEFF Research Database (Denmark)

    Vogel, Nina

    of a sustainable mobility discourse can be traced in the policy documents, how mobility is framed, and which arguments are used to legitimate or envision strategies and planning practices. Is Fredericia performing a transition towards low-carbon mobility? The paper will draw on concepts from transition theory...... urban complexity within transition processes. Transitions are always taking place, but the question is which direction they take and if these directions are in line with a planning approach for sustainable mobility....

  14. Transitional region of phase transitions in nuclear models

    Energy Technology Data Exchange (ETDEWEB)

    Kotze, A A

    1988-01-01

    The phase transition in an exactly solvable nuclear model, the Lipkin model, is scrutinised, first using Hartree-Fock methods or the plain mean flield approximation, and then using projected wave functions. It turns out that the plain mean field is not reliable in the transitional region. Although the projection methods give better resutls in the transitional region, it leads to spurious singularities. While the energy of the projection before variation is slightly better than its projection after variation counterpart, the perfomance of the wave function is considerably worse in the transitional region. The model's wave function undergoes dramatic changes in the transitional region. The mechanism that brings about these changes is studied within a model Hamiltonian that can reproduce the Lipkin model mathematically. It turns out that the numerous exceptional points found in the transitional region, bring about the change of the ground state wave function. Exceptional points are associated with level crossings in the complex plane. These level crossings can be seen as level repulsions in the spectrum. Level repulsion and a sensitive dependence of the system on some external parameter are characteristics of chaotic behaviour. These two features are found in the transitional region of the Lipkin model. In order to study chaos, one has to resort to a statistical analysis. A measure of the chaotic behaviour of systems, the ..delta../sub 3/ statistic, is introduced. The results show that the Lipkin model is harmonic, even in the transitional region. For the Lipkin model the exceptional points are regularly distributed in the complex plane. In a total chaotic system the points would be randomly distributed.

  15. Highlights from a Mach 4 Experimental Demonstration of Inlet Mode Transition for Turbine-Based Combined Cycle Hypersonic Propulsion

    Science.gov (United States)

    Foster, Lancert E.; Saunders, John D., Jr.; Sanders, Bobby W.; Weir, Lois J.

    2012-01-01

    NASA is focused on technologies for combined cycle, air-breathing propulsion systems to enable reusable launch systems for access to space. Turbine Based Combined Cycle (TBCC) propulsion systems offer specific impulse (Isp) improvements over rocket-based propulsion systems in the subsonic takeoff and return mission segments along with improved safety. Among the most critical TBCC enabling technologies are: 1) mode transition from the low speed propulsion system to the high speed propulsion system, 2) high Mach turbine engine development and 3) innovative turbine based combined cycle integration. To address these challenges, NASA initiated an experimental mode transition task including analytical methods to assess the state-of-the-art of propulsion system performance and design codes. One effort has been the Combined-Cycle Engine Large Scale Inlet Mode Transition Experiment (CCE-LIMX) which is a fully integrated TBCC propulsion system with flowpath sizing consistent with previous NASA and DoD proposed Hypersonic experimental flight test plans. This experiment was tested in the NASA GRC 10 by 10-Foot Supersonic Wind Tunnel (SWT) Facility. The goal of this activity is to address key hypersonic combined-cycle engine issues including: (1) dual integrated inlet operability and performance issues-unstart constraints, distortion constraints, bleed requirements, and controls, (2) mode-transition sequence elements caused by switching between the turbine and the ramjet/scramjet flowpaths (imposed variable geometry requirements), and (3) turbine engine transients (and associated time scales) during transition. Testing of the initial inlet and dynamic characterization phases were completed and smooth mode transition was demonstrated. A database focused on a Mach 4 transition speed with limited off-design elements was developed and will serve to guide future TBCC system studies and to validate higher level analyses.

  16. Minnowbrook IV: 2003 Workshop on Transition and Unsteady Aspects of Turbomachinery Flows

    Science.gov (United States)

    LaGraff, John E. (Editor); Ashpis, David E.

    2004-01-01

    This Minnowbrook IV 2003 workshop on Transition and Unsteady Aspects of Turbomachinery Flows includes the following topics: 1) Current Issues in Unsteady Turbomachinery Flows; 2) Global Instability and Control of Low-Pressure Turbine Flows; 3) Influence of End Wall Leakage on Secondary Flow Development in Axial Turbines; 4) Active and Passive Flow Control on Low Pressure Turbine Airfoils; 5) Experimental and Numerical Investigation of Transitional Flows as Affected by Passing Wakes; 6) Effects of Freestream Turbulence on Turbine Blade Heat Transfer; 7) Bypass Transition Via Continuous Modes and Unsteady Effects on Film Cooling; 8) High Frequency Surface Heat Flux Imaging of Bypass Transition; 9) Skin Friction and Heat Flux Oscillations in Upstream Moving Wave Packets; 10) Transition Mechanisms and Use of Surface Roughness to Enhance the Benefits of Wake Passing in LP Turbines; 11) Transient Growth Approach to Roughness-Induced Transition; 12) Roughness- and Freestream-Turbulence-Induced Transient Growth as a Bypass Transition Mechanism; 13) Receptivity Calculations as a Means to Predicting Transition; 14) On Streamwise Vortices in a Curved Wall Jet and Their Effect on the Mean Flow; 15) Plasma Actuators for Separation Control of Low Pressure Turbine Blades; 16) Boundary-Layer Separation Control Under Low-Pressure-Turbine Conditions Using Glow-Discharge Plasma Actuators; 17) Control of Separation for Low Pressure Turbine Blades: Numerical Simulation; 18) Effects of Elevated Free-Stream Turbulence on Active Control of a Separation Bubble; 19) Wakes, Calming and Transition Under Strong Adverse Pressure Gradients; 20) Transitional Bubble in Periodic Flow Phase Shift; 21) Modelling Spots: The Calmed Region, Pressure Gradient Effects and Background; 22) Modeling of Unsteady Transitional Flow on Axial Compressor Blades; 23) Challenges in Predicting Component Efficiencies in Turbomachines With Low Reynolds Number Blading; 24) Observations on the Causal Relationship Between

  17. Interdependence, issue importance, and the 2009 Russia-Ukraine gas conflict

    International Nuclear Information System (INIS)

    Lee, Yusin

    2017-01-01

    The primary aim of this paper is to explain the 2009 Russia-Ukraine gas conflict. In particular, it attempts to identify the causal mechanisms between their interdependence in the gas sphere and the gas conflict. The paper first shows that existing theories in the study of international relations have limitations in accounting for that conflict. Therefore, a theoretical framework drawing insights from Armstrong's model on dependence-political compliance and Crescenzi's exit model is proposed to explain it. Relying on this framework, this paper demonstrates that the 2009 Russia-Ukraine gas conflict took place through two critical causal mechanisms. In the contexts of the 2008 global financial crisis and Ukraine's anti-Russian policy, Russia and Ukraine both considered issues involved in the gas trade such as debts, prices, transit tariffs, and Ukraine's pipeline system to be very important. Therefore, when Russia issued demands with economic threats, Ukraine refused to comply. - Highlights: • This paper explains the 2009 Russia-Ukraine gas conflict. • It shows the causal mechanisms between their interdependent gas relations and the conflict. • The conflict took place through two critical causal mechanisms. • Russia and Ukraine considered the issues involved in the gas trade to be critical. • Thus, when Russia issued demands with economic threats, Ukraine refused to comply.

  18. The law on energy transition for a green growth

    International Nuclear Information System (INIS)

    Signoret, Stephane

    2015-01-01

    This article presents the main issues addressed by the French law on energy transition for a green growth. Thus, it evokes its main objectives and how they can be reached (notably through a control of energy demand, a wider carbon share in taxes), gives an overview of measures related to building renovation, to the development of clean transports (priority to less polluting transport modes, energy efficiency and renewable energy in transports, reduction of greenhouse gas and pollutant emissions, plan for air quality), to the struggle against wastage and to the promotion of circular economy, to the promotion of renewable energies, to the reinforcement of nuclear safety and citizen information, to the simplification and clarification of procedures, to making citizens, enterprises and State able to act together (through governance tools, the steering of electricity production, energy transition in territories, specific measures for non-interconnected areas)

  19. Which role for the nuclear in the energy transition?

    International Nuclear Information System (INIS)

    Ramade, Francois

    2013-05-01

    After having outlined the almost unavoidable character of energy transition, the author shows that a combination of nuclear and renewable energies is the single possibility to maintain a sufficient level of energy production while avoiding a major climate change. He states that the decision to shut down the Fessenheim plant is not a good start for the debate on energy transition. He outlines that the risks evoked to justify this closure are not realistic. He discusses the technical and economic consequences of this closure, how Fessenheim could then be replaced in terms of energy supply. He discusses the relationship between employment on the one side, and nuclear or renewable energies on the other side. He briefly comments the German situation, outlines that nuclear energy is an alternative to the exhaustion of fossil hydrocarbon resources. He finally addresses the issue of definition of the energy mix

  20. Using the ICF in transition research and practice? Lessons from a scoping review.

    Science.gov (United States)

    Nguyen, Tram; Stewart, Debra; Rosenbaum, Peter; Baptiste, Sue; Kraus de Camargo, Olaf; Gorter, Jan Willem

    2018-01-01

    The International Classification of Functioning, Disability and Health (ICF) and subsequent ICF-CY (child and youth version) recognize the importance of personal and environmental factors in facilitating holistic transition planning and service delivery for youth with chronic health conditions (YCHC). The objective of this scoping review is to investigate the degree to which the ICF and ICF-CY have been used in transition research and practice since its initial publication. Arksey and O'Malley's five-stage methodological framework guided the scoping review using the following databases: AMED, CINAHL, EMBASE, HealthSTAR, MEDLINE, and PsycINFO. Keywords included: 'ICF', 'ICF-CY', and 'transition', which were adapted to each database. 25 articles met final inclusion. Two key themes emerged regarding use of the ICF: 1) the ICF enhances transdisciplinary processes to inform transition planning and interventions; and 2) the ICF facilitates comprehensive and developmentally appropriate transition services over a youth's lifecourse. The strengths and limitations of the ICF in guiding the planning and delivery of transition services are discussed. Some limitations include the large number of items inherent within the ICF and a lack of clarity between the components of activity and participation. Key recommendations include: i) further explanation and development of items for quality of life and well-being, personal factors, and psychological issues; and ii) additional research to advance knowledge towards developing empirically- based evidence for the application of the ICF in clinical practice to facilitate transition. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Energy-urban transition: The Mexican case

    International Nuclear Information System (INIS)

    Paez, Armando

    2010-01-01

    In this paper I present a study regarding the institutional conditions of Mexican cities based on a post-petroleum urban model that considers transport, architecture, urban planning and land use, renewable energy sources, energy saving and efficiency, and urban metabolism issues. The model was constructed with recommendations of authors and organizations that have analysed the energy dimension of cities under an energy-availability, environmental or petroleum-independent view. To make the study I sent a questionnaire to some local governments of all the country. The information indicates that Mexican cities do not have institutional conditions to manage the urban-energy transition that signify the end of cheap oil and the peak of world oil production.

  2. Utilizing Earth Observations for Societal Issues

    Science.gov (United States)

    Habib, Shahid

    2010-01-01

    Over the last four decades a tremendous progress has been made in the Earth science space-based remote sensing observations, technologies and algorithms. Such advancements have improved the predictability by providing lead-time and accuracy of forecast in weather, climate, natural hazards, and natural resources. It has further reduced or bounded the overall uncertainties by partially improving our understanding of planet Earth as an integrated system that is governed by non-linear and chaotic behavior. Many countries such as the US, European Community, Japan, China, Russia, India has and others have invested billions of dollars in developing and launching space-based assets in the low earth (LEO) and geostationary (GEO) orbits. However, the wealth of this scientific knowledge that has potential of extracting monumental socio-economic benefits from such large investments have been slow in reaching the public and decision makers. For instance, there are a number of areas such as water resources and availability, energy forecasting, aviation safety, agricultural competitiveness, disaster management, air quality and public health, which can directly take advantage. Nevertheless, we all live in a global economy that depends on access to the best available Earth Science information for all inhabitants of this planet. This presentation discusses a process to transition Earth science data and products for societal needs including NASA's experience in achieving such objectives. It is important to mention that there are many challenges and issues that pertain to a number of areas such as: (1) difficulties in making a speedy transition of data and information from observations and models to relevant Decision Support Systems (DSS) or tools, (2) data and models inter-operability issues, (3) limitations of spatial, spectral and temporal resolution, (4) communication limitations as dictated by the availability of image processing and data compression techniques. Additionally, the

  3. Do transition towns have the potential to promote health and well-being? A health impact assessment of a transition town initiative.

    Science.gov (United States)

    Richardson, J; Nichols, A; Henry, T

    2012-11-01

    Climate change and energy vulnerability present significant challenges for the development and sustainability of our communities. The adverse effects will most likely impact on those already experiencing poverty, as energy and food costs will rise, thus increasing inequalities in health. Transition town initiatives seek to build cohesive sustainable communities to prepare for a future with limited oil and a changing climate. Increasingly, public health practitioners are interested in the role of transition towns as a community development initiative, and their potential to support the wider public health agenda. Health impact assessment (HIA) is an evidence-based process that aims to predict the positive and negative impacts of a strategy, proposal or development. The HIA process provides an opportunity to promote sustainable communities by ensuring that new strategies and developments are considered in the context of their contribution to the health and well-being of local populations. The aim of this study was to use an HIA to examine the potential health and well-being benefits of two related transition town initiatives. A rapid HIA to consider the potential lifestyle changes and health and well-being impacts of Transition Together/Transition Streets (TT/TS) projects. An HIA template was used to assess key documents related to the TT/TS initiatives and those related to the characteristics of the community. Additionally, meetings with 12 key informants (four involved in TT/TS and eight purposively selected for their local knowledge) were held using the HIA template to focus the discussion. The findings highlight the associated lifestyle changes such as increased physical activity and healthy eating, and possible social and well-being benefits of engagement in such an initiative. Engagement may be limited to those already concerned about environmental issues. This paper illustrates the important links between transition towns and the wider public health agenda

  4. The Transition Handbook: from oil dependency to local resilience; Manuel de transition. De la Dependance au Petrole a la Resilience Locale

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, Rob

    2010-10-21

    We live in an oil-dependent world, and have got to this level of dependency in a very short space of time, using vast reserves of oil in the process - without planning for when the supply is not so plentiful. Most of us avoid thinking about what happens when oil runs out (or becomes prohibitively expensive), but The Transition Handbook shows how the inevitable and profound changes ahead can have a positive outcome. These changes can lead to the rebirth of local communities, which will grow more of their own food, generate their own power, and build their own houses using local materials. They can also encourage the development of local currencies, to keep money in the local area. The book has three sections, the Head, the Heart and the Hands. The Head explores the issues of peak oil and climate change, and how when looked at together, we need to be focusing on the rebuilding of resilience as well as cutting carbon emissions. It argues that the focus of our lives will become increasingly local and small scale as we come to terms with the real implications of the energy crisis we are heading into. The Heart looks at where we find the personal tools for responding to what can feel like overwhelming challenges. It argues that key to our success will be our ability to generate positive visions of future, to harness the power of engaged optimism, and overcome powerlessness. The Hands offers a detailed exploration of the Transition model, setting out its principles, its origins, the 12 Steps of Transition, how they were applied in the first year of Transition Town Totnes, as well as offering a taste of how the model has been applied in a range of other settings. The book also contains lots of 'Tools for Transition', exercises and activities that can help to deepen this work in your community. There are now over 40 Transition Towns in the UK, with more joining as the idea takes off. With little pro-activity at government level, communities are taking matters into

  5. Semiotic systems with duality of patterning and the issue of cultural replicators.

    Science.gov (United States)

    Schaden, Gerhard; Patin, Cédric

    2017-11-14

    Two major works in recent evolutionary biology have in different ways touched upon the issue of cultural replicators in language, namely Dawkins' Selfish Gene and Maynard Smith and Szathmáry's Major Transitions in Evolution. In the latter, the emergence of language is referred to as the last major transition in evolution (for the time being), a claim we argue to be derived from a crucial property of language, called Duality of Patterning. Prima facie, this property makes natural language look like a structural equivalent to DNA, and its peer in terms of expressive power. We will argue that, if one takes seriously Maynard Smith and Szathmáry's outlook and examines what has been proposed as linguistic replicators, amongst others phonemes and words, the analogy meme-gene becomes problematic. A key issue is the fact that genes and memes are assumed to carry and transmit information, while what has been described as the best candidate for replicatorhood in language, i.e. the phoneme, does by definition not carry meaning. We will argue that semiotic systems with Duality of Pattering (like natural languages) force us to reconsider either the analogy between replicators in the biological and the cultural domain, or what it is to be a replicator in linguistics.

  6. Supporting Transition

    Science.gov (United States)

    Qureshi, Asima; Petrucco, James

    2018-01-01

    Meadowbrook Primary School has explored the use of The Teacher Assessment in Primary Science (TAPS) to support transition, initially for transfer to secondary school and now for transition from Early Years Foundation Stage (EYFS) into Key Stage 1 (ages 5-7). This article will consider an example of a secondary transition project and discuss the…

  7. Several problems of the theory of transition radiation and transition scattering

    International Nuclear Information System (INIS)

    Ginzburg, V.L.; Tsytovich, V.N.

    1979-01-01

    The process of transition radiation is a very general one. It appears if some source, which does not have a proper frequency (for example a point charge, multipole etc), is moving with a constant velocity in an inhomogeneous and/or nonstationary medium. In the case of a periodic medium the transition radiation has some special peculiarities and is called the resonance transition radiation or transition scattering. Transition scattering occurs particularly in the case when some wave of dielectric permittivity acts on a nonmoving (fixed) charge. The processes of transition radiation and transition scattering have analogies outside electrodynamics similarly to the Vavilov-Cherenkov emission. The latter occurs also for a source moving with a constant velocity but in a homogeneous medium (and only if the velocity of the source exceeds the wave phase velocity in the medium). The present review is dealing with several problems of the theory of transition radiation and transition scattering. Attention is paid mainly to the formulation of the problems and to revealing characterisic features and peculiarities of the phenomena described. (Auth.)

  8. Lightning-Discharge Initiation as a Noise-Induced Kinetic Transition

    Science.gov (United States)

    Iudin, D. I.

    2017-10-01

    The electric fields observed in thunderclouds have the peak values one order of magnitude smaller than the electric strength of air. This fact renders the issue of the lightning-discharge initiation one of the most intriguing problems of thunderstorm electricity. In this work, the lightning initiation in a thundercloud is considered as a noise-induced kinetic transition. The stochastic electric field of the charged hydrometeors is the noise source. The considered kinetic transition has some features which distinguish it from other lightning-initiation mechanisms. First, the dynamic realization of this transition, which is due to interaction of the electron and ion components, is extended for a time significantly exceeding the spark-discharge development time. In this case, the fast attachment of electrons generated by supercritical bursts of the electric field of hydrometeors is balanced during long-term time intervals by the electron-release processes when the negative ions are destroyed. Second, an important role in the transition kinetics is played by the stochastic drift of electrons and ions caused by the small-scale fluctuations of the field of charged hydrometeors. From the formal mathematical viewpoint, this stochastic drift is indistinguishable from the scalar-impurity advection in a turbulent flow. In this work, it is shown that the efficiency of "advective mixing" is several orders of magnitude greater than that of the ordinary diffusion. Third, the considered transition leads to a sharp increase in the conductivity in the exponentially rare compact regions of space against the background of the vanishingly small variations in the average conductivity of the medium. In turn, the spots with increased conductivity are polarized in the mean field followed by the streamer initiation and discharge contraction.

  9. Phase transitions and self-organized criticality in networks of stochastic spiking neurons.

    Science.gov (United States)

    Brochini, Ludmila; de Andrade Costa, Ariadne; Abadi, Miguel; Roque, Antônio C; Stolfi, Jorge; Kinouchi, Osame

    2016-11-07

    Phase transitions and critical behavior are crucial issues both in theoretical and experimental neuroscience. We report analytic and computational results about phase transitions and self-organized criticality (SOC) in networks with general stochastic neurons. The stochastic neuron has a firing probability given by a smooth monotonic function Φ(V) of the membrane potential V, rather than a sharp firing threshold. We find that such networks can operate in several dynamic regimes (phases) depending on the average synaptic weight and the shape of the firing function Φ. In particular, we encounter both continuous and discontinuous phase transitions to absorbing states. At the continuous transition critical boundary, neuronal avalanches occur whose distributions of size and duration are given by power laws, as observed in biological neural networks. We also propose and test a new mechanism to produce SOC: the use of dynamic neuronal gains - a form of short-term plasticity probably located at the axon initial segment (AIS) - instead of depressing synapses at the dendrites (as previously studied in the literature). The new self-organization mechanism produces a slightly supercritical state, that we called SOSC, in accord to some intuitions of Alan Turing.

  10. A People Extra: North Dakota and United States Situational Issues Related to and Influences upon--Families (Single Persons, Single Parents, Parent-Child, Married).

    Science.gov (United States)

    North Dakota Univ., Fargo. Dept. of Agriculture and Applied Science.

    Situational issues related to families and influences upon families in North Dakota and the United States are briefly outlined in these fact sheets. Contents specifically concern (1) outbound migration from North Dakota and transition of rural families from farming; (2) suicide in North Dakota and the nation; (3) child care issues, such as child…

  11. Lost in transition? Comparing strategies of electricity companies in Delhi

    International Nuclear Information System (INIS)

    Criqui, Laure; Zérah, Marie-Hélène

    2015-01-01

    This paper examines the notion of energy transition when implemented by private utilities. In 2000, the Delhi government privatized electricity distribution to three private distribution companies. Most research was concerned with the impact of privatization on energy reliability, tariff settings and regulation issues. This paper looks at two under-researched themes: the expansion of services to poorer neighborhoods and the rollout of clean energy policies. This focus allows to unpack the materiality of socio-technical systems, to analyze how energy infrastructures are being technically deployed on the ground and to identify which social approach is used. To detail the specific practices of each company provides a more nuanced and accurate understanding of the reform. In-depth analysis of the three private utilities show that they interpret the reform mandate differently: they use a varied range of technical tools; they respond differently to social concerns in poorer neighborhoods; and they have distinctive internal management choices and corporate cultures. All these four factors can strengthen or undermine the transition towards increased access and clean energy. - Highlights: • Energy transition in an emerging cities aims at balancing environmental and social concerns. • Utilities have distinct transition paths despite similar privatization and regulation framework. • Utilities paths depend on spatial, social, managerial and corporate considerations. • Utilities' strategies are shaped by urban challenges rather than by energy policies

  12. The political-economic transition and the building of the welfare state in Spain (1975-1986

    Directory of Open Access Journals (Sweden)

    Rafael Muñoz de Bustillo Llorente

    2008-12-01

    Full Text Available This article analyses the economic policy in Spain during the govern- ments of the Spanish political transition from 1975 to 1986. It considers the different areas of economic policy with special emphasis on the development of welfare state issues in this period. Taking into account the difficult economic and political situation in 1975, there were some important advances in social policy and progressive taxation during the period. The transition to democracy in Spain changed the role and size of the public sector above all from 1975 to 1986. The social demands over the political system were possible improvements in the progressive and redistributive policies in education, health, and social programs. Spain’s transition to democracy and the first period of welfare state show a mutually reinforcing and its consequences were the modernization of the Spanish economy. However, from 1986 the economic develop- ment and the progress of welfare state have had a different growth.Key words: Welfare state, Economic transition, Spain.

  13. Alameda-Contra Costa Transit District (AC Transit) Fuel Cell Transit Buses: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2007-03-01

    This report provides an evaluation of three prototype fuel cell-powered transit buses operating at AC Transit in Oakland, California, and six baseline diesel buses similar in design to the fuel cell buses.

  14. Coordination of IVI and transit signal priority on transit evacuations.

    Science.gov (United States)

    2011-02-01

    During an emergency evacuation, execution time is always critical to the evacuees who are : transit dependent. Transit Signal Priority (TSP) can speed up the transit services by prioritizing : the approaching bus at a signalized intersection. With th...

  15. Shedding light on energy transition

    DEFF Research Database (Denmark)

    Markovska, Natasa; Duić, Neven; Mathiesen, Brian Vad

    2018-01-01

    -carbon technologies in energy supply, buildings, transport, and industry, as well as address other key issues like demand response, co-benefits to other energy policies objectives, the role of declining costs for renewables and markets - all needed to facilitate energy sector transition. This editorial outlines......Ever since 2002, when the first Conference on Sustainable Development of Energy, Water and Environment Systems (SDEWES) was held in Dubrovnik, the SDEWES conferences series has been providing a forum for world-wide scientists and those interested in learning about the sustainability of development...... into account its economic, environmental and social pillars, as well as methods for assessing and measuring sustainability of development, regarding energy, transport, water, food production and environment systems and their many combinations. SDEWES has maintained high publishing standard as nearly 1100...

  16. Reimagining the self at late-career transitions: how identity threat influences academic physicians' retirement considerations.

    Science.gov (United States)

    Onyura, Betty; Bohnen, John; Wasylenki, Don; Jarvis, Anna; Giblon, Barney; Hyland, Robert; Silver, Ivan; Leslie, Karen

    2015-06-01

    There is scant empirical work exploring academic physicians' psychosocial adjustment during late-career transitions or on the factors that influence their retirement decisions. The authors examine these issues through the lens of sociopsychological identity theory, specifically examining how identity threat influences academic physicians' decisions about retirement. Participants were academic physicians at a Canadian medical school and were recruited via e-mail requests for clinical faculty interested in discussing late-career and retirement planning issues. Participants included 15 males and 6 females (N = 21; mean age = 63, standard deviation = 7.54), representing eight specialties (clinical and surgical). Data were collected in October and November 2012 via facilitated focus groups, which were digitally recorded, transcribed verbatim, and anonymized, then analyzed using thematic analysis. Four primary themes were identified: centrality of occupational identity, experiences of identity threat, experiences of aging in an indifferent system, and coping with late-career transitions. Identity threats were manifested in apprehensions about self-esteem after retirement, practice continuity, and clinical competence, as well as in a loss of meaning and belonging. These identity challenges influenced decisions on whether to retire. Organizational and system support was perceived as wanting. Coping strategies included reimagining and revaluing various aspects of the self through assimilating new activities and reprioritizing others. Identity-related struggles are a significant feature of academic physicians' considerations about late-career transitions. Understanding these challenges, their antecedents, and their consequences can prepare faculty, and their institutions, to better manage late-career transitions. Individual- and institution-level implications are discussed.

  17. Tool box for decision making: To start the energy transition of your territory. ADeus' Expertise - Energy November 2016

    International Nuclear Information System (INIS)

    Pons, Anne; Gendron, Yves; Isenmann, Jean; Masse, Camille; Berlet, Jessica; Estragnat, Christel; Cadenet, Pierre de; Gaugler, Karin; Jeanniard, Myriam; Kolmer, Timothe; Mallick, Amandine; Martin, Stephane; Meyer, Estelle; Muller, Lisa; Nguyen, Dong-Binh; Pous, Melanie; Ruff, Valentine

    2016-11-01

    This document presents the different steps of the decision support process for elected representatives and technicians to implement policies and actions for energy transition. It first addresses issues related to town planning where several contextual aspects must be taken into account (energy offer, energy demand, social values and individual abilities, governance level). It highlights different development options related to the development of local renewable energies, the development of energy-saving practices for households and firms, and to a contribution to energy transition competitiveness. It indicates how town and local planning tools and documents can be used to develop and implement an energy transition strategy. Three steps are thus identified: to inform local actors about their leeway, to develop a territory project which fits into energy transition, and to translate the transition strategy into a town planning document

  18. Institutions in transitioning peri-urban communities: spatial differences in groundwater access

    Science.gov (United States)

    Gomes, Sharlene L.; Hermans, Leon M.

    2016-05-01

    Urbanization creates challenges for water management in an evolving socio-economic context. This is particularly relevant in transitioning peri-urban areas like Khulna, Bangladesh where competing demands have put pressure on local groundwater resources. Users are unable to sufficiently meet their needs through existing institutions. These institutions provide the rules for service provision and act as guidelines for actors to resolve their water related issues. However, the evolving peri-urban context can produce fragmented institutional arrangements. For example in Khulna, water supply is based on urban and rural boundaries that has created water access issues for peri-urban communities. This has motivated local actors to manage their groundwater needs in various ways. General institutional theories are well developed in literature, yet little is known about institutions in transitioning peri-urban areas. Institutions that fail to adapt to changing dynamics run the risk of becoming obsolete or counter-productive, hence the need for investigating institutional change mechanisms in this context. This paper examines peri-urban case studies from Khulna using the Institutional Analysis and Development framework to demonstrate how institutions have contributed to spatial differences in groundwater access with local actors investing in formal and informal institutional change as a means of accessing groundwater.

  19. Energy transition. Consequences for Baden-Wuerttemberg; Energiewende. Implikationen fuer Baden-Wuerttemberg

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-05-15

    The Baden-Wuerttemberg Sustainability Committee (Nachhaltigkeitsbeirat Baden-Wuerttemberg, NBBW) is an independent scientific committee of 11 experts that acts in an advisory function for the state government on its way to sustainable and environment-friendly development; it accompanies the implementation and updating of the environmental plan for Baden-Wuerttemberg (Umweltplan Baden-Wuerttemberg) that was issued in December 2000. At regular intervals, the NBBW checks inhowfar the goals defined in the environmental plan have been reached and issues recommendations for better implementation. The energy transition involves particular challenges for Baden-Wuerttemberg because of the state's specific power supply structure. About 50 percent of the power supply in this German state is generated from nuclear energy. If this is to be replaced by renewable energy sources (which currently have a 17 percent share in total power generation), considerable investments are required in terms of power plants, power grids, and power storage facilities. In this publication, the NBBW advises the state government on how this can be achieved. While the NBBW supports the energy transition, it attempts to ensure that all consequences and side effects of the necessary measures will be taken into account, and that negative effects will be avoided or counteracted whenever and wherever possible.

  20. German energy policy and the way to sustainability: Five controversial issues in the debate on the “Energiewende”

    International Nuclear Information System (INIS)

    Fischer, W.; Hake, J.-Fr.; Kuckshinrichs, W.; Schröder, T.; Venghaus, S.

    2016-01-01

    German governments throughout the last 25 years have accepted the sustainability paradigm und put forth an energy policy that supports the development of renewable energies, the reduction of greenhouse gas emissions and the improvement of energy efficiency. Together with the process of seeking to phase out nuclear power, these objectives constitute the ‘Energiewende’ (energy transition) the Energiewende has reached a level that reveals its challenges and thus makes it a valuable case study. Based on a multi-method stakeholder analysis, frequently debated controversial issues related to the Energiewende have been identified and will be confronted with “reality” in this paper. The set of controversial issues includes the following five aspects: security of electricity supply, rising electricity prices for industry and commerce, rising electricity prices for consumers, impacts of the energy transition on employment, and the effects of the politically instigated speed of the Energiewende on its practical implementation.

  1. Health-illness transition among persons using advanced medical technology at home.

    Science.gov (United States)

    Fex, Angelika; Flensner, Gullvi; Ek, Anna-Christina; Söderhamn, Olle

    2011-06-01

    This study aimed to elucidate meanings of health-illness transition experiences among adult persons using advanced medical technology at home. As an increasing number of persons perform self-care while using different sorts of advanced medical technology at home, knowledge about health-illness transition experiences in this situation may be useful to caregivers in supporting these patients. A qualitative design was used. Five women and five men, all of whom performed self-care at home, either using long-term oxygen therapy from a ventilator or oxygen cylinder, or performing peritoneal or haemodialysis, were interviewed. Ethics committee approval was obtained. Informed consent was received from all participants, and ethical issues concerning their rights in research were raised. The interviews were analysed using a phenomenological hermeneutical methodology, including both an inductive and a deductive structural analysis. This method offers possibilities to obtain an increased understanding by uncovering a deeper meaning of lived experiences through interviews transcribed as texts. The health-illness transition for adult persons in this context was found to mean a learning process of accepting, managing, adjusting and improving daily life with technology, facilitated by realizing the gain from technology at home. Further, the meaning of the health-illness transition experience was interpreted as contentment with being part of the active and conscious process towards transcending into a new state of living, in which the individual and the technology were in tune. The healthy transition experience was characterized by human growth and becoming. This study elucidates one meaning of health-illness transition experiences in relation to the use of advanced medical technology on a more generic level, independent of the specific type of technology used. A positive attitude towards technology at home facilitates the transition. © 2010 The Authors. Scandinavian Journal of

  2. The future of scenarios: issues in developing new climate change scenarios

    International Nuclear Information System (INIS)

    Pitcher, Hugh M

    2009-01-01

    In September, 2007, the IPCC convened a workshop to discuss how a new set of scenarios to support climate model runs, mitigation analyses, and impact, adaptation and vulnerability research might be developed. The first phase of the suggested new approach is now approaching completion. This article discusses some of the issues raised by scenario relevant research and analysis since the last set of IPCC scenarios were created (IPCC SRES, 2000) that will need to be addressed as new scenarios are developed by the research community during the second phase. These include (1) providing a logic for how societies manage to transition from historical paths to the various future development paths foreseen in the scenarios, (2) long-term economic growth issues, (3) the appropriate GDP metric to use (purchasing power parity or market exchange rates), (4) ongoing issues with moving from the broad geographic and time scales of the emission scenarios to the finer scales needed for impacts, adaptation and vulnerability analyses and (5) some possible ways to handle the urgent request from the policy community for some guidance on scenario likelihoods. The challenges involved in addressing these issues are manifold; the reward is greater credibility and deeper understanding of an analytic tool that does much to form the context within which many issues in addition to the climate problem will need to be addressed.

  3. The future of scenarios: issues in developing new climate change scenarios

    Science.gov (United States)

    Pitcher, Hugh M.

    2009-04-01

    In September, 2007, the IPCC convened a workshop to discuss how a new set of scenarios to support climate model runs, mitigation analyses, and impact, adaptation and vulnerability research might be developed. The first phase of the suggested new approach is now approaching completion. This article discusses some of the issues raised by scenario relevant research and analysis since the last set of IPCC scenarios were created (IPCC SRES, 2000) that will need to be addressed as new scenarios are developed by the research community during the second phase. These include (1) providing a logic for how societies manage to transition from historical paths to the various future development paths foreseen in the scenarios, (2) long-term economic growth issues, (3) the appropriate GDP metric to use (purchasing power parity or market exchange rates), (4) ongoing issues with moving from the broad geographic and time scales of the emission scenarios to the finer scales needed for impacts, adaptation and vulnerability analyses and (5) some possible ways to handle the urgent request from the policy community for some guidance on scenario likelihoods. The challenges involved in addressing these issues are manifold; the reward is greater credibility and deeper understanding of an analytic tool that does much to form the context within which many issues in addition to the climate problem will need to be addressed.

  4. Quantum field theory and phase transitions: universality and renormalization group

    International Nuclear Information System (INIS)

    Zinn-Justin, J.

    2003-08-01

    In the quantum field theory the problem of infinite values has been solved empirically through a method called renormalization, this method is satisfying only in the framework of renormalization group. It is in the domain of statistical physics and continuous phase transitions that these issues are the easiest to discuss. Within the framework of a course in theoretical physics the author introduces the notions of continuous limits and universality in stochastic systems operating with a high number of freedom degrees. It is shown that quasi-Gaussian and mean field approximation are unable to describe phase transitions in a satisfying manner. A new concept is required: it is the notion of renormalization group whose fixed points allow us to understand universality beyond mean field. The renormalization group implies the idea that long distance correlations near the transition temperature might be described by a statistical field theory that is a quantum field in imaginary time. Various forms of renormalization group equations are presented and solved in particular boundary limits, namely for fields with high numbers of components near the dimensions 4 and 2. The particular case of exact renormalization group is also introduced. (A.C.)

  5. Which transition comes first? Urban and demographic transitions in Belgium and Sweden

    Directory of Open Access Journals (Sweden)

    Philippe Bocquier

    2015-12-01

    Full Text Available Background: Several theories compete to explain the main drivers of urbanisation, past and present, in relation to both demographic transition and economic development. One hypothesis is that rural-to-urban migration is the driver of urbanisation; another is that urban mortality decline actually triggered urban transition. Objective: This paper reconsiders the relationship between demographic (vital migration and urban transitions by analysing the long-term contribution of natural and migratory movements to urban transition. The respective contributions of birth, death, and migration and their timing will indicate whether economic development, through labour force migration, or vital transition mainly determines urban transition. Methods: After examining the spatial dimension of the demographic transition theory, we use 19th and 20th century series on Sweden and Belgium to better identify the migration component of urban transition through the computation of growth difference between urban and rural areas, accounting for the often neglected reclassification effect. Results: In both Sweden and Belgium, migration is the direct or indirect (through reclassification engine of urban transition and its contribution precedes the onset of vital transition, while the vital transition has a secondary, unstable, and negative role in the urban transition. Conclusions: Changes in the economic sphere are reinstated as the underlying cause of population change, acting through the shift of human capital in space. Methodological consequences are then drawn for analysing vital and urban transitions in an increasingly interdependent world. Contribution: The paper contributes to the theoretical literature on urban and demographic transitions in relation to economic development. The proposed method evaluates migration contribution without having to measure it.

  6. Efficiently reducing transition curvature in heat-assisted magnetic recording with state-of-the-art write heads

    Science.gov (United States)

    Vogler, Christoph; Abert, Claas; Bruckner, Florian; Suess, Dieter

    2017-05-01

    Curvatures of bit transitions on granular media are a serious problem for the read-back process. We address this fundamental issue and propose a possibility to efficiently reduce transition curvatures with state-of-the-art heat-assisted magnetic recording heads. We compare footprints of conventional with those of the proposed head design on different media, consisting of exchange coupled and single phase grains. Additionally, we investigate the impact of various recording parameters, such as the full width at half maximum (FWHM) of the applied heat pulse and the coercivity gradient near the write temperature of the recording grains. The footprints are calculated with a coarse grained model, based on the Landau-Lifshitz-Bloch equation. The presented simulations show a transition curvature reduction of up to 40%, in the case of a medium with exchange coupled grains and a heat pulse with a FWHM of 40 nm. We further give the reason for the straightening of the bit transitions, by means of basic considerations with regard to the effective recording time window of the write process. Besides the transition curvature reduction, the proposed head design yields an improvement of the transition jitter in both down-track and off-track directions.

  7. Know Your Client and Know Your Team: A Complexity Inspired Approach to Understanding Safe Transitions in Care

    Directory of Open Access Journals (Sweden)

    Deborah Tregunno

    2013-01-01

    Full Text Available Background. Transitions in care are one of the most important and challenging client safety issues in healthcare. This project was undertaken to gain insight into the practice setting realities for nurses and other health care providers as they manage increasingly complex care transitions across multiple settings. Methods. The Appreciative Inquiry approach was used to guide interviews with sixty-six healthcare providers from a variety of practice settings. Data was collected on participants’ experience of exceptional care transitions and opportunities for improving care transitions. Results. Nurses and other healthcare providers need to know three things to ensure safe care transitions: (1 know your client; (2 know your team on both sides of the transfer; and (3 know the resources your client needs and how to get them. Three themes describe successful care transitions, including flexible structures; independence and teamwork; and client and provider focus. Conclusion. Nurses often operate at the margins of acceptable performance, and flexibility with regulation and standards is often required in complex sociotechnical work like care transitions. Priority needs to be given to creating conditions where nurses and other healthcare providers are free to creatively engage and respond in ways that will optimize safe care transitions.

  8. Incumbent Decisions about Succession Transitions in Family Firms: A Conceptual Model

    OpenAIRE

    Britta Boyd; Isabel C. Botero; Tomasz A. Fediuk

    2014-01-01

    In the family business literature, succession research has focused on the family member as they enter the leadership role or on the different issues that affect the succession process. Although researchers have acknowledged that succession in family businesses is “punctuated” by decision making events, less attention has been given to understanding how incumbents make decisions about ownership and management transitions. In an effort to continue to understand the succession process it is impo...

  9. Nonlinear process in the mode transition in typical strut-based and cavity-strut based scramjet combustors

    Science.gov (United States)

    Yan, Li; Liao, Lei; Huang, Wei; Li, Lang-quan

    2018-04-01

    The analysis of nonlinear characteristics and control of mode transition process is the crucial issue to enhance the stability and reliability of the dual-mode scramjet engine. In the current study, the mode transition processes in both strut-based combustor and cavity-strut based combustor are numerically studied, and the influence of the cavity on the transition process is analyzed in detail. The simulations are conducted by means of the Reynolds averaged Navier-Stokes (RANS) equations coupled with the renormalization group (RNG) k-ε turbulence model and the single-step chemical reaction mechanism, and this numerical approach is proved to be valid by comparing the predicted results with the available experimental shadowgraphs in the open literature. During the mode transition process, an obvious nonlinear property is observed, namely the unevenly variations of pressure along the combustor. The hysteresis phenomenon is more obvious upstream of the flow field. For the cavity-strut configuration, the whole flow field is more inclined to the supersonic state during the transition process, and it is uneasy to convert to the ramjet mode. In the scram-to-ram transition process, the process would be more stable, and the hysteresis effect would be reduced in the ram-to-scram transition process.

  10. Understanding Transgender and Medically Assisted Gender Transition: Feminism as a Critical Resource.

    Science.gov (United States)

    Nelson, Jamie Lindemann

    2016-11-01

    Feminism has fought the trivialization of women's experiences, championed women's security, and insisted on respect for women's choices. In so doing, feminism has developed important perspectives on the complicated connections between what gender means as it plays itself in people's lives, and the inequalities of power and authority that structure much of human experience. Here, I put a few of these perspectives into contact with an issue where the interactions of gender and power are squarely in play: medicine's role in assisting gender transitioning generally and, specifically, the enduring controversy between medicine and many transgender people about the pathologization of transgender and the role of clinicians as gatekeepers to gender-transition interventions. © 2016 American Medical Association. All Rights Reserved.

  11. Transit-Based Emergency Evacuation with Transit Signal Priority in Sudden-Onset Disaster

    Directory of Open Access Journals (Sweden)

    Ciyun Lin

    2016-01-01

    Full Text Available This study presents methods of transit signal priority without transit-only lanes for a transit-based emergency evacuation in a sudden-onset disaster. Arterial priority signal coordination is optimized when a traffic signal control system provides priority signals for transit vehicles along an evacuation route. Transit signal priority is determined by “transit vehicle arrival time estimation,” “queuing vehicle dissipation time estimation,” “traffic signal status estimation,” “transit signal optimization,” and “arterial traffic signal coordination for transit vehicle in evacuation route.” It takes advantage of the large capacities of transit vehicles, reduces the evacuation time, and evacuates as many evacuees as possible. The proposed methods were tested on a simulation platform with Paramics V6.0. To evaluate and compare the performance of transit signal priority, three scenarios were simulated in the simulator. The results indicate that the methods of this study can reduce the travel times of transit vehicles along an evacuation route by 13% and 10%, improve the standard deviation of travel time by 16% and 46%, and decrease the average person delay at a signalized intersection by 22% and 17% when the traffic flow saturation along an evacuation route is 0.81.0, respectively.

  12. The Ukrainian energetic system under the light of the crisis: beyond gas transit, a governance challenge

    International Nuclear Information System (INIS)

    Boulanger, Quentin

    2014-01-01

    The objective of this report is to address and describe the problematic of the Ukrainian gas transit within a wider inner context and under the light of the current gas crisis. Beyond the European security of supply, maintaining the gas transit is a major domestic issue for Ukraine, from an economic as well as political point of view. This means that, in order to avoid a new gas crisis, Ukraine must significantly reform its energy sector in order to reduce its dependency and to re-balance its energy mix. In a first part, the author discusses gas price and transit network management as the main stakes of the gas crisis: recall of traditional dispute about gas between Russia and Ukraine, ageing and corruption as characteristics of a collapsing gas corridor, the Ukrainian law of September 2014 as a first step for a reform of energy governance. In a second part, the author discusses the future of the Ukrainian gas sector and the issue of stability of the national energy system. This should be based on short term options to strengthen the resilience of the gas sector in front of Russian supply disruption, a priority for a gas independence, and necessary review of the energy mix

  13. 75 FR 26683 - Hospital and Outpatient Care for Veterans Released From Incarceration to Transitional Housing

    Science.gov (United States)

    2010-05-12

    ... difficulty obtaining similar treatment during a transitional period. In particular, if mental health issues... housing upon release from incarceration in a prison or jail. The proposed rule would permit VA to work with these veterans while they are in these programs with the goal of continuing to work with them...

  14. Energy transition and transport networks, the Danish example. Breakfast-debate of 4 April 2013

    International Nuclear Information System (INIS)

    Boucly, Philippe; Dorte Riggelsen, Anne; Lambert, Francois-Michel; Brabo, Torben; Bornard, Pierre

    2013-01-01

    This document contains contributions presented by the GRTgaz general manager, the Danish ambassador, an expert in circular economy, the vice-chairman of the Danish gas and electricity utility, and a high representative of RTE about the role of energy transport networks in energy transition. It appears that energy transition raises several issues for energy transport operators: technical challenges due to the growth of renewable energies (notably in terms of grid steering and of production and consumption peak management), the introduction of flexibility and development of energy storage means, mechanisms of solidarity between regions and countries, political and economic dimensions with exchanges on good practices

  15. Renewable energies. Ambivalences, governance, legal issues; Erneuerbare Energien. Ambivalenzen, Governance, Rechtsfragen

    Energy Technology Data Exchange (ETDEWEB)

    Ekardt, Felix; Hennig, Bettina; Unnerstall, Herwig (eds.)

    2012-07-01

    The present publication is dedicated to renewable energies. The move to a new energy and climate policy impinges on many central humanistic issues (including issues of a legal, economic, sociological, ethical and politological nature). How is it possible to resolve the ambivalences that are associated with the use of renewable energies and which draw our attention not only to renewable energies as such but also to issues of energy efficiency and sufficiency. What political and economic instruments are needed in order to accelerate the market entry of renewable energies and at the same time contain the ambivalences associated with them? And what questions of legal interpretation result from the application of such instruments in practice, be it in the context of subsidies under the Renewable Energy Law or the laws on the planning of building projects. And where lie the causes of the fact seen here that so many individuals in business, the political realm and the public at large are finding it hard to go with the transition to renewable energies?.

  16. Primary Issues of Mixed Convection Heat Transfer Phenomena

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Myeong-Seon; Chung, Bum-Jin [Kyung Hee University, Yongin (Korea, Republic of)

    2015-10-15

    The computer code analyzing the system operating and transient behavior must distinguish flow conditions involved with convective heat transfer flow regimes. And the proper correlations must be supplied to those flow regimes. However the existing safety analysis codes are focused on the Light Water Reactor and they are skeptical to be applied to the GCRs (Gas Cooled Reactors). One of the technical issues raise by the development of the VHTR is the mixed convection, which occur when the driving forces of both forced and natural convection are of comparable magnitudes. It can be encountered as in channel of the stacked with fuel elements and a decay heat removal system and in VHTR. The mixed convection is not intermediate phenomena with natural convection and forced convection but independent complicated phenomena. Therefore, many researchers have been studied and some primary issues were propounded for phenomena mixed convection. This paper is to discuss some problems identified through reviewing the papers for mixed convection phenomena. And primary issues of mixed convection heat transfer were proposed respect to thermal hydraulic problems for VHTR. The VHTR thermal hydraulic study requires an indepth study of the mixed convection phenomena. In this study we reviewed the classical flow regime map of Metais and Eckert and derived further issues to be considered. The following issues were raised: (1) Buoyancy aided an opposed flows were not differentiated and plotted in a map. (2) Experimental results for UWT and UHF condition were also plotted in the same map without differentiation. (3) The buoyancy coefficient was not generalized for correlating with buoyancy coefficient. (4) The phenomenon analysis for laminarization and returbulization as buoyancy effects in turbulent mixed convection was not established. (5) The defining to transition in mixed convection regime was difficult.

  17. The transitional region of phase transitions in nuclear models

    International Nuclear Information System (INIS)

    Kotze, A.A.

    1988-01-01

    The phase transition in an exactly solvable nuclear model, the Lipkin model, is scrutinised, first using Hartree-Fock methods or the plain mean flield approximation, and then using projected wave functions. It turns out that the plain mean field is not reliable in the transitional region. Although the projection methods give better resutls in the transitional region, it leads to spurious singularities. While the energy of the projection before variation is slightly better than its projection after variation counterpart, the perfomance of the wave function is considerably worse in the transitional region. The model's wave function undergoes dramatic changes in the transitional region. The mechanism that brings about these changes is studied within a model Hamiltonian that can reproduce the Lipkin model mathematically. It turns out that the numerous exceptional points found in the transitional region, bring about the change of the ground state wave function. Exceptional points are associated with level crossings in the complex plane. These level crossings can be seen as level repulsions in the spectrum. Level repulsion and a sensitive dependence of the system on some external parameter are characteristics of chaotic behaviour. These two features are found in the transitional region of the Lipkin model. In order to study chaos, one has to resort to a statistical analysis. A measure of the chaotic behaviour of systems, the Δ 3 statistic, is introduced. The results show that the Lipkin model is harmonic, even in the transitional region. For the Lipkin model the exceptional points are regularly distributed in the complex plane. In a total chaotic system the points would be randomly distributed

  18. Phase transitions

    CERN Document Server

    Sole, Ricard V; Solé, Ricard V; Solé, Ricard V; Sol, Ricard V; Solé, Ricard V

    2011-01-01

    Phase transitions--changes between different states of organization in a complex system--have long helped to explain physics concepts, such as why water freezes into a solid or boils to become a gas. How might phase transitions shed light on important problems in biological and ecological complex systems? Exploring the origins and implications of sudden changes in nature and society, Phase Transitions examines different dynamical behaviors in a broad range of complex systems. Using a compelling set of examples, from gene networks and ant colonies to human language and the degradation of diverse ecosystems, the book illustrates the power of simple models to reveal how phase transitions occur. Introductory chapters provide the critical concepts and the simplest mathematical techniques required to study phase transitions. In a series of example-driven chapters, Ricard Solé shows how such concepts and techniques can be applied to the analysis and prediction of complex system behavior, including the origins of ...

  19. The Avahan Transition: Effects of Transition Readiness on Program Institutionalization and Sustained Outcomes.

    Directory of Open Access Journals (Sweden)

    Sachiko Ozawa

    Full Text Available With declines in development assistance for health and growing interest in country ownership, donors are increasingly faced with the task of transitioning health programs to local actors towards a path to sustainability. Yet there is little available guidance on how to measure and evaluate the success of a transition and its subsequent effects. This study assesses the transition of the Avahan HIV/AIDS prevention program in India to investigate how preparations for transition affected continuation of program activities post-transition.Two rounds of two surveys were conducted and supplemented by data from government and Avahan Computerized Management Information Systems (CMIS. Exploratory factor analysis was used to develop two measures: 1 transition readiness pre-transition, and 2 institutionalization (i.e. integration of initial program systems into organizational procedures and behaviors post-transition. A fixed effects model was built to examine changes in key program delivery outcomes over time. An ordinary least square regression was used to assess the relationship between transition readiness and sustainability of service outcomes both directly, and indirectly through institutionalization.Transition readiness data revealed 3 factors (capacity, alignment and communication, on a 15-item scale with adequate internal consistency (alpha 0.73. Institutionalization was modeled as a unidimensional construct, and a 12-item scale demonstrated moderate internal consistency (alpha 0.60. Coverage of key populations and condom distribution were sustained compared to pre-transition levels (p<0.01. Transition readiness, but not institutionalization, predicted sustained outcomes post-transition. Transition readiness did not necessarily lead to institutionalization of key program elements one year after transition.Greater preparedness prior to transition is important to achieve better service delivery outcomes post-transition. This paper illustrates a

  20. International regulatory issues and approaches in the transition phase from operation to decommissioning

    International Nuclear Information System (INIS)

    Pyy, P.; Hrehor, M.; ); Murley, T.; Ranieri, R.; Laaksonen, J.

    2005-01-01

    Full text: The paper summarizes the work performed by an international group of senior nuclear safety regulators which was convened by the Committee on Nuclear Regulatory Activities (CNRA) of the OECD/Nuclear Energy Agency. The fundamental objective of this work was to identify the safety, environmental, organizational, human factors and public policy issues arising from decommissioning that will produce new challenges for the regulator. The study begins by recognizing that decommissioning is not simply an extension of operation and thus it is important for both the management of the facility and the regulator to understand the fundamental nature of the change taking place. Major regulatory policy issues discussed during this study include assurance of adequate funds, waste storage and disposal sites, material release criteria and site release criteria. Some of the important regulatory challenges relate to organizational and human factors, to safety and security requirements and to waste disposal and license termination. The importance of regular communication with both the corporate and site management and with public is recognized in the study as one of the key factors. When a nuclear facility ceases operation and enters into the decommissioning phase, both the operator and the regulator face a new set of challenges very different from those of an operating facility. The operator should have in place a strategic plan for decommissioning, prepared well in advance and reviewed by the regulatory body, to guide the facility managers and personnel through the changed circumstances. An essential part of the strategic plan should be the operator's plan for securing adequate funds to complete the decommissioning activities. In fact, the regulator should ensure that the operator sets aside funds, perhaps in a trust fund, while the facility is still operating and generating revenues. Both the operator and the regulator should expect a heightened public interest and concern

  1. Labour Market Trends in Transition Economies with Emphasis on Gender Inequalities

    Directory of Open Access Journals (Sweden)

    Theranda Beqiri

    2016-08-01

    Full Text Available Main purpose of this research paper is to show the recent trends of labour market issues regarding gender inequality in the countries that are still in the transition to the market oriented economy. Transition to competition has effected in increasing the level of unemployment to economically active population, with the higher consequence for females than for males, from which some females have left labour market and they became inactive in job searching. In this paper we analyze and compare gender gaps through the main components of labour market trends as level of education, active participation in labour market, occupational segregation, employment and unemployment for both genders of the countries that are still in transition like Albania, FYR of Macedonia and Kosovo in comparison with EU countries. Given that closer are these countries in joining the EU; higher are the requirements for increasing the level of employment targets and in approving and implementing social policies on gender equality in labour market according to the EU legislations. Methodology used in this paper is through case studies by using secondary data from the most recent labour force surveys (LFS of transition countries in South East Europe and comparing them with the EU targets. Also regarding occupational segregation by gender the Duncan & Duncan Index is calculated. The study shows that depending on the stages that countries are in transition earlier or latter, the labour market components regarding gender are more comparable and closer with the targets of the EU countries, and that occupational segregation is higher in the transition countries where the unemployment level of females is in the higher range.

  2. Cosmological phase transitions

    International Nuclear Information System (INIS)

    Kolb, E.W.

    1993-10-01

    If modern ideas about the role of spontaneous symmetry breaking in fundamental physics are correct, then the Universe should have undergone a series of phase transitions early in its history. The study of cosmological phase transitions has become an important aspect of early-Universe cosmology. In this lecture I review some very recent work on three aspects of phase transitions: the electroweak transition, texture, and axions

  3. Eigenstate Phase Transitions

    Science.gov (United States)

    Zhao, Bo

    Phase transitions are one of the most exciting physical phenomena ever discovered. The understanding of phase transitions has long been of interest. Recently eigenstate phase transitions have been discovered and studied; they are drastically different from traditional thermal phase transitions. In eigenstate phase transitions, a sharp change is exhibited in properties of the many-body eigenstates of the Hamiltonian of a quantum system, but not the thermal equilibrium properties of the same system. In this thesis, we study two different types of eigenstate phase transitions. The first is the eigenstate phase transition within the ferromagnetic phase of an infinite-range spin model. By studying the interplay of the eigenstate thermalization hypothesis and Ising symmetry breaking, we find two eigenstate phase transitions within the ferromagnetic phase: In the lowest-temperature phase the magnetization can macroscopically oscillate by quantum tunneling between up and down. The relaxation of the magnetization is always overdamped in the remainder of the ferromagnetic phase, which is further divided into phases where the system thermally activates itself over the barrier between the up and down states, and where it quantum tunnels. The second is the many-body localization phase transition. The eigenstates on one side of the transition obey the eigenstate thermalization hypothesis; the eigenstates on the other side are many-body localized, and thus thermal equilibrium need not be achieved for an initial state even after evolving for an arbitrary long time. We study this many-body localization phase transition in the strong disorder renormalization group framework. After setting up a set of coarse-graining rules for a general one dimensional chain, we get a simple "toy model'' and obtain an almost purely analytical solution to the infinite-randomness critical fixed point renormalization group equation. We also get an estimate of the correlation length critical exponent nu

  4. Evaluation of a FRET-peptide substrate to predict virulence in Pseudomonas aeruginosa.

    Directory of Open Access Journals (Sweden)

    Wendy E Kaman

    Full Text Available Pseudomonas aeruginosa produces a number of proteases that are associated with virulence and disease progression. A substrate able to detect P. aeruginosa-specific proteolytic activity could help to rapidly alert clinicians to the virulence potential of individual P. aeruginosa strains. For this purpose we designed a set of P. aeruginosa-specific fluorogenic substrates, comprising fluorescence resonance energy transfer (FRET-labeled peptides, and evaluated their applicability to P. aeruginosa virulence in a range of clinical isolates. A FRET-peptide comprising three glycines (3xGly was found to be specific for the detection of P. aeruginosa proteases. Further screening of 97 P. aeruginosa clinical isolates showed a wide variation in 3xGly cleavage activity. The absence of 3xGly degradation by a lasI knock out strain indicated that 3xGly cleavage by P. aeruginosa could be quorum sensing (QS-related, a hypothesis strengthened by the observation of a strong correlation between 3xGly cleavage, LasA staphylolytic activity and pyocyanin production. Additionally, isolates able to cleave 3xGly were more susceptible to the QS inhibiting antibiotic azithromycin (AZM. In conclusion, we designed and evaluated a 3xGly substrate possibly useful as a simple tool to predict virulence and AZM susceptibility.

  5. Formulation design of oral pediatric Acetazolamide suspension: dose uniformity and physico-chemical stability study.

    Science.gov (United States)

    Santoveña, Ana; Suárez-González, Javier; Martín-Rodríguez, Cristina; Fariña, José B

    2017-03-01

    The formulation of an active pharmaceutical ingredient (API) as oral solution or suspension in pediatrics is a habitual practice, due to the non-existence of many commercialized medicines in pediatric doses. It is also the simplest way to prepare and administer them to this vulnerable population. The design of a formulation that assures the dose and the system stability depends on the physico-chemical properties of the API. In this study, we formulate a class IV API, Acetazolamide (AZM) as suspension for oral administration to pediatric population. The suspension must comply attributes of quality, safety and efficacy for this route of administration. We use simple compounding procedures, as well as fewer pure excipients, as recommended for children. Mass and uniformity content assays and physical and chemical stability studies were performed. To quantify the API an UPLC method was used. We verified the physico-chemical stability of the suspensions and that they passed the mass test of the European Pharmacopeia (EP), but not the dose uniformity test. This reveals that AZM must be formulated as liquid forms with a more complex system of excipients (not usually indicated in pediatrics), or otherwise solid forms capable of assuring uniformity of mass and dose for every dosage unit.

  6. Phase transitions, double-scaling limit, and topological strings

    International Nuclear Information System (INIS)

    Caporaso, Nicola; Griguolo, Luca; Pasquetti, Sara; Marino, Marcos; Seminara, Domenico

    2007-01-01

    Topological strings on Calabi-Yau manifolds are known to undergo phase transitions at small distances. We study this issue in the case of perturbative topological strings on local Calabi-Yau threefolds given by a bundle over a two-sphere. This theory can be regarded as a q-deformation of Hurwitz theory, and it has a conjectural nonperturbative description in terms of q-deformed 2D Yang-Mills theory. We solve the planar model and find a phase transition at small radius in the universality class of 2D gravity. We give strong evidence that there is a double-scaled theory at the critical point whose all-genus free energy is governed by the Painleve I equation. We compare the critical behavior of the perturbative theory to the critical behavior of its nonperturbative description, which belongs to the universality class of 2D supergravity, and we comment on possible implications for nonperturbative 2D gravity. We also give evidence for a new open/closed duality relating these Calabi-Yau backgrounds to open strings with framing

  7. Pumped storage system model and experimental investigations on S-induced issues during transients

    Science.gov (United States)

    Zeng, Wei; Yang, Jiandong; Hu, Jinhong

    2017-06-01

    Because of the important role of pumped storage stations in the peak regulation and frequency control of a power grid, pump turbines must rapidly switch between different operating modes, such as fast startup and load rejection. However, pump turbines go through the unstable S region in these transition processes, threatening the security and stability of the pumped storage station. This issue has mainly been investigated through numerical simulations, while field experiments generally involve high risks and are difficult to perform. Therefore, in this work, the model test method was employed to study S-induced security and stability issues for a pumped storage station in transition processes. First, a pumped storage system model was set up, including the piping system, model units, electrical control systems and measurement system. In this model, two pump turbines with different S-shaped characteristics were installed to determine the influence of S-shaped characteristics on transition processes. The model platform can be applied to simulate any hydraulic transition process that occurs in real power stations, such as load rejection, startup, and grid connection. On the experimental platform, the S-shaped characteristic curves were measured to be the basis of other experiments. Runaway experiments were performed to verify the impact of the S-shaped characteristics on the pump turbine runaway stability. Full load rejection tests were performed to validate the effect of the S-shaped characteristics on the water-hammer pressure. The condition of one pump turbine rejecting its load after another defined as one-after-another (OAA) load rejection was performed to validate the possibility of S-induced extreme draft tube pressure. Load rejection experiments with different guide vane closing schemes were performed to determine a suitable scheme to adapt the S-shaped characteristics. Through these experiments, the threats existing in the station were verified, the

  8. Empirical study of the impact of corruption on entrepreneurship in transition economies

    OpenAIRE

    Duong, Phuong Thanh

    2015-01-01

    In this study, we attempt to understand the current level of corruption and the development of entrepreneurship in transition economies. Based on that knowledge, we strike to develop concrete empirical results revealing the impacts of corruption on entrepreneurship in these special economies. After that, recommendations to address the issues are proposed. In particular, we focus on promoting structural and institutional reforms emphasizing on the importance of the privatization process. Our i...

  9. Non-Fourier heat conduction and phase transition in laser ablation of polytetrafluoroethylene (PTFE)

    Science.gov (United States)

    Zhang, Yu; Zhang, Daixian; Wu, Jianjun; Li, Jian; He, Zhaofu

    2017-11-01

    The phase transition in heat conduction of polytetrafluoroethylene-like polymers was investigated and applied in many fields of science and engineering. Considering more details including internal absorption of laser radiation, reflectivity of material and non-Fourier effect etc., the combined heat conduction and phase transition in laser ablation of polytetrafluoroethylene were modeled and investigated numerically. The thermal and mechanic issues in laser ablation were illustrated and analyzed. Especially, the phenomenon of temperature discontinuity formed in the combined phase transition and non-Fourier heat conduction was discussed. Comparisons of target temperature profiles between Fourier and non-Fourier heat conduction in melting process were implemented. It was indicated that the effect of non-Fourier plays an important role in the temperature evolvement. The effect of laser fluence was proven to be significant and the thermal wave propagation was independent on the laser intensity for the non-Fourier heat conduction. Besides, the effect of absorption coefficients on temperature evolvements was studied. For different ranges of absorption coefficients, different temperature evolvements can be achieved. The above numerical simulation provided insight into physical processes of combined non-Fourier heat conduction and phase transition in laser ablation.

  10. Environmental, health, and safety issues of fuel cells in transportation. Volume 1: Phosphoric acid fuel-cell buses

    Energy Technology Data Exchange (ETDEWEB)

    Ring, S

    1994-12-01

    The U.S. Department of Energy (DOE) chartered the Phosphoric Acid Fuel-Cell (PAFC) Bus Program to demonstrate the feasibility of fuel cells in heavy-duty transportation systems. As part of this program, PAFC- powered buses are being built to meet transit industry design and performance standards. Test-bed bus-1 (TBB-1) was designed in 1993 and integrated in March 1994. TBB-2 and TBB-3 are under construction and should be integrated in early 1995. In 1987 Phase I of the program began with the development and testing of two conceptual system designs- liquid- and air-cooled systems. The liquid-cooled PAFC system was chosen to continue, through a competitive award, into Phase H, beginning in 1991. Three hybrid buses, which combine fuel-cell and battery technologies, were designed during Phase III. After completing Phase II, DOE plans a comprehensive performance testing program (Phase HI) to verify that the buses meet stringent transit industry requirements. The Phase III study will evaluate the PAFC bus and compare it to a conventional diesel bus. This NREL study assesses the environmental, health, and safety (EH&S) issues that may affect the commercialization of the PAFC bus. Because safety is a critical factor for consumer acceptance of new transportation-based technologies the study focuses on these issues. The study examines health and safety together because they are integrally related. In addition, this report briefly discusses two environmental issues that are of concern to the Environmental Protection Agency (EPA). The first issue involves a surge battery used by the PAFC bus that contains hazardous constituents. The second issue concerns the regulated air emissions produced during operation of the PAFC bus.

  11. Federal Transit Administration's noise and vibration Guidance Manual: Updates after 10 years of experience

    Science.gov (United States)

    Hanson, Carl E.

    2005-09-01

    In April 1995, the Federal Transit Administration of the U.S. Department of Transportation issued its guidance manual, ``Transit Noise and Vibration Impact Assessment.'' The manual was written to provide direction for the preparation of noise and vibration sections of environmental documents for public transportation projects in the interest of promoting quality and uniformity in assessments. In the 10 years since its release, the guidance manual has been used as the basis of noise and vibration assessments in over 80 environmental documents and has been used worldwide as a standard method for performing transit noise analyses. An updated version has recently been prepared that takes account of improvements in tools, changes in the environmental assessment procedures, modifications of impact criteria, and experience with mitigation measures. These factors, and other background information, will be discussed to provide insight regarding the revisions in the new edition.

  12. Signals for the QCD phase transition and critical point in a Langevin dynamical model

    International Nuclear Information System (INIS)

    Herold, Christoph; Bleicher, Marcus; Yan, Yu-Peng

    2013-01-01

    The search for the critical point is one of the central issues that will be investigated in the upcoming FAIR project. For a profound theoretical understanding of the expected signals we go beyond thermodynamic studies and present a fully dynamical model for the chiral and deconfinement phase transition in heavy ion collisions. The corresponding order parameters are propagated by Langevin equations of motions on a thermal background provided by a fluid dynamically expanding plasma of quarks. By that we are able to describe nonequilibrium effects occurring during the rapid expansion of a hot fireball. For an evolution through the phase transition the formation of a supercooled phase and its subsequent decay crucially influence the trajectories in the phase diagram and lead to a significant reheating of the quark medium at highest baryon densities. Furthermore, we find inhomogeneous structures with high density domains along the first order transition line within single events.

  13. Challenges in the transition toward a hydrogen-based society. An in-depth study to assess the potential of a transition to a hydrogen-based energy supply in Europe

    International Nuclear Information System (INIS)

    Mourik, R.; De Groot, A.; Jeeninga, H.

    2006-12-01

    The Hysociety project, financed under the FP5 framework of the European Commission, aimed to contribute to European policies on hydrogen-related issues through the development of an action plan for the introduction of hydrogen. The geographic target was Europe, focusing on the 15 European Union member states, plus Norway and Iceland. In addition, demonstration projects in Canada, the United States, Japan, Brazil, and China were analyzed. Work package 1 addressed the technological, infrastructural, ecological, economic, political, and cultural challenges of the transition to a hydrogen-based society. The work built upon an analysis of the challenges identified in demonstration projects in all participating countries. In this article we first discuss the transition theory and the methodology used in Hysociety work package 1 and conclude with a discussion of results of the Hysociety project

  14. THE ROLE OF CORPORATE GOVERNANCE IN TRANSITION ECONOMIES: CONTRIBUTION AND DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    OLIVERA GJORGIEVA-TRAJKOVSKA

    2016-10-01

    Full Text Available With more evident process of globalization of the world market, the concept of corporate governance gains importance. The global economic crisis highlighted the problems of corporate governance both in developed countries and developing economies. Analyzing the effects of the global economic crisis, including striking collapse of many companies, the huge increase in unemployment and the increased number of people living on the poverty line and below, it can be concluded that some of these problems are result of various weaknesses and failures of corporate governance. Even though the introduction of a number of rules, codes and practices of corporate governance have been made, the global economic crisis has shown that more effective application of the standards of corporate governance is necessary. Corporate governance issues are especially important in transition economies, since these countries do not have the long-established financial institution infrastructure to deal with corporate governance issues. Before 1989 there was no need to discuss corporate governance issues, because all enterprises were owned by the state and there were no shareholders. All that has changed. This paper discusses the importance of corporate governance, with special reference to transition economies. Directors, owners and corporate managers have started to realize that there are benefits that can accrue from having a good corporate governance structure. Good corporate governance helps to increase share price and makes it easier to obtain capital. International investors are hesitant to lend money or buy shares in a corporation that does not subscribe to good corporate governance principles. Transparency, independent directors and a separate audit committee are especially important.

  15. Dosimetric Properties of Plasma Density Effects on Laser-Accelerated VHEE Beams Using a Sharp Density-Transition Scheme

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Seung Hoon; Cho, Sungho; Kim, Eun Ho; Park, Jeong Hoon; Jung, Won-Gyun; Kim, Geun Beom; Kim, Kum Bae [Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Min, Byung Jun [Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Kim, Jaehoon [Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Jeong, Hojin [Gyeongsang National University Hospital, Jinju (Korea, Republic of); Lee, Kitae [Korea Atomic Energy Research Institute, Deajeon (Korea, Republic of); Park, Sung Yong [Karmanos Cancer Institute, Michigan (United States)

    2017-01-15

    In this paper, the effects of the plasma density on laser-accelerated electron beams for radiation therapy with a sharp density transition are investigated. In the sharp density-transition scheme for electron injection, the crucial issue is finding the optimum density conditions under which electrons injected only during the first period of the laser wake wave are accelerated further. In this paper, we report particle-in-cell simulation results for the effects of both the scale length and the density transition ratio on the generation of a quasi-mono-energetic electron bunch. The effects of both the transverse parabolic channel and the plasma length on the electron-beam's quality are investigated. Also, we show the experimental results for the feasibility of a sharp density-transition structure. The dosimetric properties of these very high-energy electron beams are calculated using Monte Carlo simulations.

  16. Ethnography of epidemiologic transition: Avian flu, global health politics and agro-industrial capitalism in Thailand.

    Science.gov (United States)

    Chuengsatiansup, Komatra

    2008-04-01

    This paper situates the ethnography of avian flu within the geo-political context of a new epidemiologic transition. Drawing on anthropological experience and insight, this paper examines areas of enquiry in which an ethnographic approach could contribute to a better implementation of prevention and control measures. Within the context of newly emerging diseases and accelerated globalization, the task of ethnography needs to extend far beyond the local. This paper reveals two major global issues that the ethnography of epidemiologic transition must take into consideration: (1) Global agro-industrial capitalism, and (2) global politics in the context of international health organizations and multi-national drug companies. The case of Thailand poses a question of how the strength of ethnographic practice could be deployed to account for the reality of the global-local interface of the new epidemiologic transition.

  17. Stoppage in transit and right of control : 'Conflict of rules' ?

    Directory of Open Access Journals (Sweden)

    Časlav Pejović

    2009-08-01

    Full Text Available Stoppage in transit is a common law mechanism of protection of unpaid seller aimed at protecting the seller against the risk of non payment of the price. This seller’s right has been adopted in a modified form by the UN Convention on the International Sale of Goods (CISG. On the other hand, under the rules of maritime law, there is the right of control over the goods performed by the holder of all originals of the negotiable transport document. The stoppage in transit, as defined by the CISG contravenes the right of control under the maritime law rules, particularly in civil law jurisdictions, where the seller does not have the right to stop the goods in transit, unless he is in possession of all originals of a transport document. This ‘conflict of rules’ became apparent after the UNCITRAL draft of the Convention on Contracts for the International Carriage of Goods Wholly or Partly by Sea was adopted in July 2008. Differently from all previous conventions regulating carriage of goods by sea, this UNCITRAL Draft expressly regulates the issue of right of control during the carriage. Under those provisions, the right of control is in the hands of the holder of all originals of a transport document. Hence, under the UNCITRAL Draft the seller does not have the right to stop the goods in transit, unless he is the holder of all originals of a transport document, which is in conflict with the CISG provision on the stoppage in transit. This paper analyzes this ‘conflict of rules’ of these two conventions which were, interestingly, adopted by the same international organization.

  18. Breast Cancer Survivorship: A Comprehensive Review of Long-Term Medical Issues and Lifestyle Recommendations

    Science.gov (United States)

    Bodai, Balazs I; Tuso, Phillip

    2015-01-01

    Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good news, but clinicians must also recognize that this brings new challenges to the medical community. As breast cancer becomes a chronic condition rather than a life-threatening illness owing to advances in early diagnosis and more effective treatments, health care practitioners must recognize and manage the long-term sequelae of the constellation of therapeutic modalities. Survivors of breast cancer represent a unique and extremely complex group of patients; not only do they have the challenge of dealing with multiple long-term side effects of treatment protocols, but many are also forced to address the preexisting comorbidities of their therapies, which often include multiple other issues. Therapies have additional and/or additive side effects that may interfere with treatments directed toward the new primary diagnosis of breast cancer. Our mandate is to establish a smooth transition from patient with breast cancer to survivor of breast cancer while providing ongoing and future guidance. Certainly, the information and resources to accomplish this transition are readily available; however, they are scattered throughout the literature and therefore are not easily accessible or available to the primary care physician. It is imperative that the information available regarding survivorship issues be accessible in an organized and useful format. This article is a modest attempt to provide a comprehensive review of the long-term medical issues relevant to survivorship after the diagnosis and treatment of breast cancer. A predicted shortage of oncologists by 2020 is well-recognized. Therefore, the bulk of long-term care will become dependent on the primary care physician. This shift of care means that these physicians will need to be well educated in the long-term medical issues related to breast cancer treatment. PMID:25902343

  19. Transition to the Ultimate Regime in Two-Dimensional Rayleigh-Bénard Convection

    Science.gov (United States)

    Zhu, Xiaojue; Mathai, Varghese; Stevens, Richard J. A. M.; Verzicco, Roberto; Lohse, Detlef

    2018-04-01

    The possible transition to the so-called ultimate regime, wherein both the bulk and the boundary layers are turbulent, has been an outstanding issue in thermal convection, since the seminal work by Kraichnan [Phys. Fluids 5, 1374 (1962), 10.1063/1.1706533]. Yet, when this transition takes place and how the local flow induces it is not fully understood. Here, by performing two-dimensional simulations of Rayleigh-Bénard turbulence covering six decades in Rayleigh number Ra up to 1 014 for Prandtl number Pr =1 , for the first time in numerical simulations we find the transition to the ultimate regime, namely, at Ra*=1013 . We reveal how the emission of thermal plumes enhances the global heat transport, leading to a steeper increase of the Nusselt number than the classical Malkus scaling Nu ˜Ra1 /3 [Proc. R. Soc. A 225, 196 (1954), 10.1098/rspa.1954.0197]. Beyond the transition, the mean velocity profiles are logarithmic throughout, indicating turbulent boundary layers. In contrast, the temperature profiles are only locally logarithmic, namely, within the regions where plumes are emitted, and where the local Nusselt number has an effective scaling Nu ˜Ra0.38 , corresponding to the effective scaling in the ultimate regime.

  20. Three lifestyle-related issues of major significance for public health among the Inuit in contemporary Greenland: a review of adverse childhood conditions, obesity, and smoking in a period of social transition.

    Science.gov (United States)

    Bjerregaard, Peter; Larsen, Christina V L

    2018-01-01

    Greenland is a country in transition from a colonial past with subsistence hunting and fishing to an urban Nordic welfare state. Epidemiological transition from infectious to chronic diseases has been evident since the 1950s. Ninety percent of the population is Inuit. We studied three public health issues based on published literature, namely adverse childhood experiences, addictive behavior, and suicide; diet and obesity; and smoking. Alcohol consumption was high in the 1970s and 1980s with accompanying family and social disruption. This is still a cause of poor mental health and suicides in the generations most affected. The diet is changing from a traditional diet of fish and marine mammals to imported food including food items rich in sugar and fat from domestic animals, and the level of physical activity is decreasing with an ensuing epidemic rise in obesity. The prevalence of smoking is high at around 60% among both men and women and is only slowly decreasing. Smoking shows large social variation, and tobacco-related diseases are widespread. The diseases and conditions outlined above all contribute towards a low life expectancy at birth-69 years for men and 74 years for women in 2011-2015-compared with 78 and 84 years for men and women, respectively, on average in the European countries. The translation of government public health programs into local activities needs strengthening, and it must be realized that the improvement of public health is a long-term process.

  1. Energy: Transitions and Reshaping

    International Nuclear Information System (INIS)

    Hache, Emmanuel; Mazzucchi, Nicolas; Alex, Bastien; Tchung-Ming, Stephane; Meritet, Sophie; Mignon, Valerie; Fischer-Herzog, Claude; Baccarini, Luca; Karbuz, Sohbet; Carcanague, Samuel; Noreng, Oesteyn; Luciani, Giacomo; Criqui, Patrick

    2016-01-01

    This issue of 'Revue internationale et strategique' from Winter 2016 presents a special dossier about the geopolitics of energy in a transitional and reshaping market. Content: Introduction: A New Age for Energy Markets? (Emmanuel Hache); National vs International Oil Companies: Toward a New Balance (Nicolas Mazzucchi); Can OPEC Survive Oil Abundance? (Emmanuel Hache); Dutch Disease and Low Oil Prices: From Economic Bankruptcy to (geo)political Reshaping (Bastien Alex, Stephane Tchung-Ming); Is Energy a Driving Force in American Foreign Policy? (Sophie Meritet); Oil Prices and U.S. Dollar: Two Sides of the Same Power? (Valerie Mignon ); The EU's Energy Union: What Energy Security for Europe? (Claude Fischer-Herzog); Natural Gas Discoveries and the Future of the Eastern Mediterranean Region (Luca Baccarini, Sohbet Karbuz); The Two Years that Changed the Caspian Sea region (Samuel Carcanague); On Oil and Islam (Oeystein Noreng); Middle East: clean energy sources and the diversification of the oil economies? (Giacomo Luciani); After the Paris Agreement, the New Geopolitics of Energy Innovations (Patrick Criqui)

  2. Relieving the Impact of Transit Signal Priority on Passenger Cars through a Bilevel Model

    Directory of Open Access Journals (Sweden)

    Ding Wang

    2017-01-01

    Full Text Available Transit signal priority (TSP is an effective control strategy to improve transit operations on the urban network. However, the TSP may sacrifice the right-of-way of vehicles from side streets which have only few transit vehicles; therefore, how to minimize the negative impact of TSP strategy on the side streets is an important issue to be addressed. Concerning the typical mixed-traffic flow pattern and heavy transit volume in China, a bilevel model is proposed in this paper: the upper-level model focused on minimizing the vehicle delay in the nonpriority direction while ensuring acceptable delay variation in transit priority direction, and the lower-level model aimed at minimizing the average passenger delay in the entire intersection. The parameters which will affect the efficiency of the bilevel model have been analyzed based on a hypothetical intersection. Finally, a real-world intersection has been studied, and the average vehicle delay in the nonpriority direction decreased 11.28 s and 22.54 s (under different delay variation constraint compared to the models that only minimize average passenger delay, while the vehicle delay in the priority direction increased only 1.37 s and 2.87 s; the results proved the practical applicability and efficiency of the proposed bilevel model.

  3. Esophageal Transit, Contraction and Perception of Transit After Swallows of Two Viscous Boluses.

    Science.gov (United States)

    Dalmazo, Jucileia; Aprile, Lilian Rose Otoboni; Dantas, Roberto Oliveira

    2015-10-01

    There have been results showing the influence of bolus viscosities and consistency on esophageal motility and transit. However, there is no description about the influence of two different viscous boluses on esophageal contractions, bolus transit and perception of transit. Our objective in this investigation was to evaluate the esophageal transit and contraction after swallows of two viscous boluses. By impedance and manometric methods, we measured the esophageal transit and contraction after swallows of two viscous boluses of 5 mL volume, 100% barium sulfate and yogurt, swallowed in duplicate in the supine and upright positions. The bolus transit, esophageal contractions and the perception of bolus transit through the esophagus were evaluated in both positions. Impedance and contraction were measured at 5, 10, 15 and 20 cm from the lower esophageal sphincter. After each swallow, the volunteers were asked about the sensation of bolus transit through the esophagus. In supine position, the yogurt had a less frequent complete bolus transit than barium. Also in the supine position, the esophageal transit was longer with yogurt than with barium. Esophageal contractions after swallows were similar between barium and yogurt boluses. There was no difference in perception of transit between the two boluses. Although both 100% barium sulfate and yogurt are viscous boluses and have similar viscosities, the transit through the esophagus is slower with yogurt bolus than with barium bolus, which suggests that viscosity may be not the sole factor to determine transit.

  4. Transit manager's handbook.

    Science.gov (United States)

    2011-09-01

    This handbook provides an overview of public transit in Iowa and how to do business with the Iowa Department of Transportation (Iowa DOT) Office of Public Transit (OPT). It is intended to be a tool to assist transit managers navigate through the many...

  5. Using Problem-Based Learning to help Portuguese students make the Bologna transition

    Directory of Open Access Journals (Sweden)

    Manuel Cabral Reis

    2013-08-01

    Full Text Available The Bologna Declaration has opened a stage of big and deep changes in the internal university organization, external cooperation, teaching models and methods, among other., all over the European countries. Here we will present and discuss a pilot experience conducted at the Engineering Department of the University of Trás-os-Montes e Alto Douro, Portugal, during the second year of that transition period. In brief, we will present a set of non-mandatory courses proposed to the students of each individual syllabus, with one hundred hours duration, each, approximately seven hours/week, fifteen weeks long, with the permanent help of a specialized trainer to aid the students in their "homework". The formal bureaucratic transition is also presented. Design and implementation issues, supported on problem-based learning and experimental lab learning classes, final assessment results, as well as the opinion of the students, are presented and analyzed. We believe that this methodology helped to make the transition smoother to the students, but also to the teaching staff.

  6. Design and evaluation of a prelicensure interprofessional course on improving care transitions.

    Science.gov (United States)

    Heflin, Mitchell T; Pinheiro, Sandro O; Konrad, Thomas R; Egerton, Emily O; Thornlow, Deirdre K; White, Heidi K; McConnell, Eleanor J

    2014-01-01

    Effective management of care transitions for older adults require the coordinated expertise of an interprofessional team. Unfortunately, different health care professions are rarely educated together or trained in teamwork skills. To address this issue, a team of professionally diverse faculty from the Duke University Geriatric Education Center designed an interprofessional course focused on improving transitions of care for older adults. This innovative prelicensure course provided interactive teaching sessions designed to promote critical thinking and foster effective communication among health care professionals, caregivers, and patients. Students were assessed by in-class and online participation, performance on individual assignments, and team-based proposals to improve care transitions for older patients with congestive heart failure. Twenty students representing six professions completed the course; 18 completed all self-efficacy and course evaluation surveys. Students rated their self-efficacy in several domains before and after the course and reported gains in teamwork skills (p competence (p work. This course offers a promising approach to shifting the paradigm of health professions education to empower graduates to promote quality improvement through team-based care.

  7. Contestation, contingency, and justice in the Nordic low-carbon energy transition

    International Nuclear Information System (INIS)

    Sovacool, Benjamin K.

    2017-01-01

    The five Nordic countries have aggressive climate and energy policies in place and have already emerged to be leaders in renewable energy and energy efficiency. Denmark is renowned for its pioneering use of wind energy, Finland and Sweden bioenergy, Norway hydroelectricity and Iceland geothermal energy. All countries aim to be virtually “fossil free” by 2050. This study explores the Nordic energy transition through the lens of three interconnected research questions: How are they doing it? What challenges exist? And what broader lessons result for energy policy? The study firstly investigates the pathways necessary for these five countries to achieve their low-carbon goals. It argues that a concerted effort must be made to (1) promote decentralized and renewable forms of electricity supply; (2) shift to more sustainable forms of transport; (3) further improve the energy efficiency of residential and commercial buildings; and (4) adopt carbon capture and storage technologies for industry. However, the section that follows emphasizes some of the empirical barriers the Nordic transition must confront, namely political contestation, technological contingency, and social justice and recognition concerns. The study concludes with implications for what such historical progress, and future transition pathways, mean for both energy researchers and energy planners. - Highlights: • Nordic countries have strong energy and climate policies to be practically “fossil free” by 2050. • Decarbonization and transition pathways depend on renewable energy, efficiency, transport, and industry. • The Nordic transition remains contingent on further technological innovations and policy commitments. • It also raises energy justice issues concerning employment, public knowledge, and embodied emissions.

  8. Economic System and Transition Mode : A Comparative Research on Transition Economies

    OpenAIRE

    Yang, Liu

    2014-01-01

    This passage mainly deals with the problem of why different transition countries have different transition mode and different economic performance. According to this research, it has been found that the economic system of the traditional socialist countries played an important role in their process of reform and transition. The socialist countries with their different economic systems had determined the economic performance, the space, as well as the environment of the transition. All of this...

  9. Contemporary Transitional Justice

    DEFF Research Database (Denmark)

    Gissel, Line Engbo

    2017-01-01

    This article studies the contemporary expression of transitional justice, a field of practice through which global governance is exercised. It argues that transitional justice is being normalised, given the normative and empirical de-legitimisation of its premise of exceptionalism. The article...... theorises exceptionalism and normalcy in transitional justice and identifies three macro-level causes of normalisation: the legalisation, internationalisation, and professionalization of the field. This argument is illustrated by a study of Uganda’s trajectory of transitional justice since 1986. Across five...... phases of transitional justice, processes of legalisation, internationalisation, and professionalization have contributed to the gradual dismantling of the country’s exceptional justice. The case demonstrates, further, that normalization is a contested and incomplete process....

  10. Transitional care management in the outpatient setting.

    Science.gov (United States)

    Baldonado, Analiza; Hawk, Ofelia; Ormiston, Thomas; Nelson, Danielle

    2017-01-01

    Patients who are high risk high cost (HRHC), those with severe or multiple medical issues, and the chronically ill elderly are major drivers of rising health care costs.1 The HRHC patients with complex health conditions and functional limitations may likely go to emergency rooms and hospitals, need more supportive services, and use long-term care facilities.2 As a result, these patient populations are vulnerable to fragmented care and "falling through the cracks".2 A large county health and hospital system in California, USA introduced evidence-based interventions in accordance with the Triple AIM3 focused on patient-centered health care, prevention, health maintenance, and safe transitions across the care continuum. The pilot program embedded a Transitional Care Manager (TCM) within an outpatient Family Medicine clinic to proactively assist HRHC patients with outreach assistance, problem-solving and facilitating smooth transitions of care. This initiative is supported by a collaborative team that included physicians, nurses, specialists, health educator, and pharmacist. The initial 50 patients showed a decrease in Emergency Department (ED) encounters (pre-vs post intervention: 33 vs 17) and hospital admissions (pre-vs post intervention: 32 vs 11), improved patient outcomes, and cost saving. As an example, one patient had 1 ED visit and 5 hospital admission with total charges of $217,355.75 in the 6 months' pre-intervention with no recurrence of ED or hospital admissions in the 6 months of TCM enrollment. The preliminary findings showed improvement of patient-centered outcomes, quality of care, and resource utilization however more data is required.

  11. Draft European resolution on energy transition within the European Union. Nr 597

    International Nuclear Information System (INIS)

    Michels, Thierry

    2018-01-01

    After references to European and international directives or agreements, this document aims at drawing up new flexible rules to promote energy transition within the EU. It therefore states the French National Assembly opinion on issues related to the reduction of European greenhouse emissions, the revision of the Carbon Emissions Trading Scheme, rules concerning the sharing of the burden to reduce these emissions in sectors not covered by the ETS, the revision of rules concerning energy efficiency and the energy performance of buildings, the revision of rules concerning renewable energies, the revision of rules in the electric power sector, the governance of the Union of energy, the revision of rules concerning the Agency of the Cooperation of Energy Regulators, the consideration of social impacts of energy transition, the Brexit, and the Paris agreement

  12. Transitional Justice as Elite Justice? Compromise Justice and Transition in Tunisia

    NARCIS (Netherlands)

    Lamont, Christopher; Pannwitz, Hannah

    2016-01-01

    This article reflects upon the ways in which transitional justice debates and processes impacted Tunisia's transition. It explores key questions such as what demands for justice emerged in the aftermath of the Tunisian revolution? Did Tunisia's transitional justice process reflect these demands?

  13. Environmental issues elimination through circular economy

    Energy Technology Data Exchange (ETDEWEB)

    Špirková, M., E-mail: marta.spirkova@stuba.sk; Pokorná, E.; Šujanová, J.; Samáková, J. [Paulínska 16, 917 24 Trnava, Slovakia, Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava (Slovakia)

    2016-04-21

    Environmental efforts of European Union are currently going towards circular economy. Tools like Extended Producer Responsibility and Eco-design were established. The circular economy deals with resources availability issue on one hand and waste management on the other hand. There are few pioneering companies all over the world with some kind of circular economy practice. Generally the concept is not very wide-spread. The paper aims to evaluate possibility of transition towards circular economy in Slovak industrial companies. They need to have an active approach to material treatment of their products after usage stage. Innovation is another important pre-condition for the transition. Main problem of current cradle to grave system is landfilling of valuable materials after one cycle of usage. Their potential value for next manufacturing cycles is lost. Companies may do not see connection between waste management and material resource prices and volatility of supplies. Municipalities are responsible for municipal waste collection and treatment in Slovakia. The circular economy operates by cradle to cradle principle. Company manages material flow until the material comes back to the beginning of manufacturing process by itself or by another partners. Stable material supplies with quite low costs are provided this way. It is necessary to deal with environmental problems in phase of product design. Questionnaire survey results show on one hand low involvement of industrial companies in waste management area, however on the other hand they are open to environmental innovations in future.

  14. Environmental issues elimination through circular economy

    International Nuclear Information System (INIS)

    Špirková, M.; Pokorná, E.; Šujanová, J.; Samáková, J.

    2016-01-01

    Environmental efforts of European Union are currently going towards circular economy. Tools like Extended Producer Responsibility and Eco-design were established. The circular economy deals with resources availability issue on one hand and waste management on the other hand. There are few pioneering companies all over the world with some kind of circular economy practice. Generally the concept is not very wide-spread. The paper aims to evaluate possibility of transition towards circular economy in Slovak industrial companies. They need to have an active approach to material treatment of their products after usage stage. Innovation is another important pre-condition for the transition. Main problem of current cradle to grave system is landfilling of valuable materials after one cycle of usage. Their potential value for next manufacturing cycles is lost. Companies may do not see connection between waste management and material resource prices and volatility of supplies. Municipalities are responsible for municipal waste collection and treatment in Slovakia. The circular economy operates by cradle to cradle principle. Company manages material flow until the material comes back to the beginning of manufacturing process by itself or by another partners. Stable material supplies with quite low costs are provided this way. It is necessary to deal with environmental problems in phase of product design. Questionnaire survey results show on one hand low involvement of industrial companies in waste management area, however on the other hand they are open to environmental innovations in future.

  15. Environmental issues elimination through circular economy

    Science.gov (United States)

    Špirková, M.; Pokorná, E.; Šujanová, J.; Samáková, J.

    2016-04-01

    Environmental efforts of European Union are currently going towards circular economy. Tools like Extended Producer Responsibility and Eco-design were established. The circular economy deals with resources availability issue on one hand and waste management on the other hand. There are few pioneering companies all over the world with some kind of circular economy practice. Generally the concept is not very wide-spread. The paper aims to evaluate possibility of transition towards circular economy in Slovak industrial companies. They need to have an active approach to material treatment of their products after usage stage. Innovation is another important pre-condition for the transition. Main problem of current cradle to grave system is landfilling of valuable materials after one cycle of usage. Their potential value for next manufacturing cycles is lost. Companies may do not see connection between waste management and material resource prices and volatility of supplies. Municipalities are responsible for municipal waste collection and treatment in Slovakia. The circular economy operates by cradle to cradle principle. Company manages material flow until the material comes back to the beginning of manufacturing process by itself or by another partners. Stable material supplies with quite low costs are provided this way. It is necessary to deal with environmental problems in phase of product design. Questionnaire survey results show on one hand low involvement of industrial companies in waste management area, however on the other hand they are open to environmental innovations in future.

  16. Motivations for enterprise system adoption in transition economies: insights from Poland

    Science.gov (United States)

    Soja, Piotr; Weistroffer, Heinz Roland

    2016-06-01

    Enterprise system (ES) adoption can bring many benefits, but may also put tremendous strain on an organisation or business, sometimes with disastrous outcomes. The specific motivations and expectations that lead to ES adoption may impact the success or failure of these endeavours, and understanding these motivations may be useful in predicting the success of ES projects. Most of the published research on ES adoption motivation has been in the context of highly developed countries. The social, cultural, economic and political conditions in developing, emerging and transition economies make for a different business environment, and insights obtained from developed countries may not always transfer to these settings. This study seeks to identify and help understand the motivations for ES adoption specifically in transition economies, as these economies play a significant role in the global market, but have not been receiving adequate research attention. Drawing on the experience of 129 ES adopters in Poland, a transition economy, this study categorises motivations into coherent groups of issues and evaluates the influence of discovered motivations on ES adoption success. Further, motivations revealed by this study are compared with motivations reported by prior research conducted in developed countries.

  17. Overcoming energy injustice? Bulgaria’s renewable energy transition in times of crisis

    OpenAIRE

    Andreas, Jan-Justus; Burns, Charlotte Jennie; Touza-Montero, Julia Maria

    2018-01-01

    The effects of renewable energy transitions on energy costs and economic growth have led to cost concerns and a prioritisation of economic issues during the economic crisis. Bulgaria, the EU's poorest state has nevertheless already achieved its 2020 renewable energy targets. This achievement seems to challenge the widely held as- sumption that poorer countries struggle to meet environmental objectives. This paper analyses the drivers and implications of Bulgaria's renewables expansion in orde...

  18. Initial Clinical Experience Performing Patient Treatment Verification With an Electronic Portal Imaging Device Transit Dosimeter

    Energy Technology Data Exchange (ETDEWEB)

    Berry, Sean L., E-mail: BerryS@MSKCC.org [Department of Applied Physics and Applied Mathematics, Columbia University, New York, New York (United States); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Polvorosa, Cynthia; Cheng, Simon; Deutsch, Israel; Chao, K. S. Clifford; Wuu, Cheng-Shie [Department of Radiation Oncology, Columbia University, New York, New York (United States)

    2014-01-01

    Purpose: To prospectively evaluate a 2-dimensional transit dosimetry algorithm's performance on a patient population and to analyze the issues that would arise in a widespread clinical adoption of transit electronic portal imaging device (EPID) dosimetry. Methods and Materials: Eleven patients were enrolled on the protocol; 9 completed and were analyzed. Pretreatment intensity modulated radiation therapy (IMRT) patient-specific quality assurance was performed using a stringent local 3%, 3-mm γ criterion to verify that the planned fluence had been appropriately transferred to and delivered by the linear accelerator. Transit dosimetric EPID images were then acquired during treatment and compared offline with predicted transit images using a global 5%, 3-mm γ criterion. Results: There were 288 transit images analyzed. The overall γ pass rate was 89.1% ± 9.8% (average ± 1 SD). For the subset of images for which the linear accelerator couch did not interfere with the measurement, the γ pass rate was 95.7% ± 2.4%. A case study is presented in which the transit dosimetry algorithm was able to identify that a lung patient's bilateral pleural effusion had resolved in the time between the planning CT scan and the treatment. Conclusions: The EPID transit dosimetry algorithm under consideration, previously described and verified in a phantom study, is feasible for use in treatment delivery verification for real patients. Two-dimensional EPID transit dosimetry can play an important role in indicating when a treatment delivery is inconsistent with the original plan.

  19. Matter in transition

    International Nuclear Information System (INIS)

    Anderson, Lara B.; Gray, James; Raghuram, Nikhil; Taylor, Washington

    2016-01-01

    We explore a novel type of transition in certain 6D and 4D quantum field theories, in which the matter content of the theory changes while the gauge group and other parts of the spectrum remain invariant. Such transitions can occur, for example, for SU(6) and SU(7) gauge groups, where matter fields in a three-index antisymmetric representation and the fundamental representation are exchanged in the transition for matter in the two-index antisymmetric representation. These matter transitions are realized by passing through superconformal theories at the transition point. We explore these transitions in dual F-theory and heterotic descriptions, where a number of novel features arise. For example, in the heterotic description the relevant 6D SU(7) theories are described by bundles on K3 surfaces where the geometry of the K3 is constrained in addition to the bundle structure. On the F-theory side, non-standard representations such as the three-index antisymmetric representation of SU(N) require Weierstrass models that cannot be realized from the standard SU(N) Tate form. We also briefly describe some other situations, with groups such as Sp(3), SO(12), and SU(3), where analogous matter transitions can occur between different representations. For SU(3), in particular, we find a matter transition between adjoint matter and matter in the symmetric representation, giving an explicit Weierstrass model for the F-theory description of the symmetric representation that complements another recent analogous construction.

  20. Perspective: Entering uncharted waters: navigating the transition from trainee to career for the nonphysician clinician-scientist.

    Science.gov (United States)

    MacDonald, Shannon E; Sharpe, Heather M; Shikako-Thomas, Keiko; Larsen, Bodil; MacKay, Lyndsay

    2013-01-01

    The transition from trainee to career clinician-scientist can be a stressful and challenging time, particularly for those entering the less established role of nonphysician clinician-scientist. These individuals are typically PhD-prepared clinicians in the allied health professions, who have either a formal or informal joint appointment between a clinical institution and an academic or research institution. The often poorly defined boundaries and expectations of these developing roles can pose additional challenges for the trainee-to-career transition.It is important for these trainees to consider what they want and need in a position in order to be successful, productive, and fulfilled in both their professional and personal lives. It is also critical for potential employers, whether academic or clinical (or a combination of both), to be fully aware of the supports and tools necessary to recruit and retain new nonphysician clinician-scientists. Issues of relevance to the trainee and the employer include finding and negotiating a position; the importance of mentorship; the value of effective time management, particularly managing clinical and academic time commitments; and achieving work-life balance. Attention to these issues, by both the trainee and those in a position to hire them, will facilitate a smooth transition to the nonphysician clinician-scientist role and ultimately contribute to individual and organizational success.

  1. Managing the Transition: The Role of Optimism and Self-Efficacy for First-Year Australian University Students

    Science.gov (United States)

    Morton, Stephen; Mergler, Amanda; Boman, Peter

    2014-01-01

    Students making the transition from high school to university often encounter many stressors and new experiences. Many students adjust successfully to university; however, some students do not, often resulting in attrition from the university and mental health issues. The primary aim of the current study was to examine the effects that optimism,…

  2. Correlation between defect transition levels and thermoelectric operational temperature of doped CrSi2

    Science.gov (United States)

    Singh, Abhishek; Pandey, Tribhuwan

    2014-03-01

    The performance of a thermoelectric material is quantified by figure of merit ZT. The challenge in achieving high ZT value requires simultaneously high thermopower, high electrical conductivity and low thermal conductivity at optimal carrier concentration. So far doping is the most versatile approach used for modifying thermoelectric properties. Previous studies have shown that doping can significantly improve the thermoelectric performance, however the tuning the operating temperature of a thermoelectric device is a main issue. Using first principles density functional theory, we report for CrSi2, a linear relationship between thermodynamic charge state transition levels of defects and temperature at which thermopower peaks. We show for doped CrSi2 that the peak of thermopower occurs at the temperature Tm, which corresponds to the position of defect transition level. Therefore, by modifying the defect transition level, a thermoelectric material with a given operational temperature can be designed. The authors thankfully acknowledge support from ADA under NpMASS.

  3. Stress induces pain transition by potentiation of AMPA receptor phosphorylation.

    Science.gov (United States)

    Li, Changsheng; Yang, Ya; Liu, Sufang; Fang, Huaqiang; Zhang, Yong; Furmanski, Orion; Skinner, John; Xing, Ying; Johns, Roger A; Huganir, Richard L; Tao, Feng

    2014-10-08

    Chronic postsurgical pain is a serious issue in clinical practice. After surgery, patients experience ongoing pain or become sensitive to incident, normally nonpainful stimulation. The intensity and duration of postsurgical pain vary. However, it is unclear how the transition from acute to chronic pain occurs. Here we showed that social defeat stress enhanced plantar incision-induced AMPA receptor GluA1 phosphorylation at the Ser831 site in the spinal cord and greatly prolonged plantar incision-induced pain. Interestingly, targeted mutation of the GluA1 phosphorylation site Ser831 significantly inhibited stress-induced prolongation of incisional pain. In addition, stress hormones enhanced GluA1 phosphorylation and AMPA receptor-mediated electrical activity in the spinal cord. Subthreshold stimulation induced spinal long-term potentiation in GluA1 phosphomimetic mutant mice, but not in wild-type mice. Therefore, spinal AMPA receptor phosphorylation contributes to the mechanisms underlying stress-induced pain transition. Copyright © 2014 the authors 0270-6474/14/3413737-10$15.00/0.

  4. The Dynamics of Hope and Motivations in Groups Working on Complex Societal Issues

    Directory of Open Access Journals (Sweden)

    Pia Andersson

    2016-01-01

    Full Text Available This paper reports results from a study of how participants’ sense of personal hope and motivation was affected by a facilitated process in which four groups of people worked on different complex social issues. The group interventions were designed to scaffold increased understanding of the complexity of the chosen issue. A method called The Integral Process for Working on Complex Issues was used in all of the groups. Issues addressed in the four groups were: neighborhood deterioration, lack of community engagement, the need for better strategies for communication between rescue service actors in critical life-and-death situations, and transition to a more environmentally sustainable city. The study investigated the participants’ self-reported changes in their levels of hope regarding the possibility of achieving positive results on the selected issue, and changes in their motivation to engage in work to that end. The data were gathered through interviews with individual group participants before and after the group process. The sessions supported group members to develop more awareness of the complexity of the issues, and to develop strategies for action. The study indicates that the discovery of new potential pathways to manage an issue, through a more comprehensive understanding of the complexity involved, was a key factor influencing levels of hope and motivation. Reports from participants showed that when the participants formulated concrete actions that made sense to them, then “particularized hope” emerged, as well as motivation to continue to engage. Thus, increased levels of hope about a delimited part of the issue were reported, while in some cases, participants reported having less hope about the issue complex as a whole.

  5. The School-to-Community Transition of Hearing-Impaired Persons with Developmental Disabilities: A Review of the Empirical Literature.

    Science.gov (United States)

    Davis, Cheryl; Bullis, Michael

    1990-01-01

    This article summarizes 43 empirical studies of school-to-community transition of hearing-impaired persons with developmental disabilities; discusses data collection and interpretation issues; and recommends future research, development, and evaluation. The studies deal with such areas as career/vocational preparation, independent living skills,…

  6. Study of the phase transition dynamics of the L to H transition

    International Nuclear Information System (INIS)

    Moyer, R.A.; Rhodes, T.L.; Rettig, C.L.

    1997-12-01

    A highly radiating zone (MARFE) just above the divertor X-point has been used to access the marginal transition regime P sep ∼ P thres to study the existence of a critical point for the L to H transition. Phase transition models predict that at the critical point, the transition duration increases and the plasma parameters vary continuously between L-mode and H-mode. In these experiments, the L to H transition duration increased 50--100 times over fast transitions. However, the evolution of E r shear, edge density gradient, H-mode pedestal, and fluctuations is essentially unchanged from that in fast transitions. The only difference is in the speed with which and the degree to which the fluctuation amplitudes are transiently reduced. This difference is understandable in terms of the time scales for fluctuation amplitude reduction (≤ 100 micros) and edge pressure gradient increase (several ms), provided the edge fluctuations are pressure-gradient driven

  7. Migration: a core public health ethics issue.

    Science.gov (United States)

    Wild, V; Dawson, A

    2018-05-01

    In this article, we outline the link between migration, public health and ethics. Discussing relevant arguments about migration from the perspective of public health and public health ethics. Critical review of theories and frameworks, case-based analysis and systematic identification and discussion of challenges. Migration is a core issue of public health ethics and must take a case-based approach: seeking to identify the specific ethical dimensions and vulnerabilities in each particular context. Public health as a practice, built upon the core value of justice, requires the protection and promotion of migrants' well-being (even if this produces tension with immigration services). Ethical analysis should take all phases of migration into account: before, during and after transit. We argue that migration policies, at least as they relate to migrants' well-being, should be founded upon a shared humanity, respect for human rights and on the idea that effective public health cannot and should not be confined within the borders and to the citizens of any host country. We make the case for migration to be seen as a core issue of public health ethics. Copyright © 2018 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  8. Postsecondary Transitions for Youth in Appalachia's Central Subregions: A Review of Education Research, 1995-2015

    Science.gov (United States)

    Kannapel, Patricia J.; Flory, Michael A.

    2017-01-01

    This article reviews research on issues surrounding postsecondary transitions for youth in middle (North Central, Central, and South Central) Appalachia, a region that faces numerous education challenges because of its geography, poverty, and economy. Examining published research and data from 1995 to 2015, the review seeks to inform education…

  9. Cosmological phase transitions

    International Nuclear Information System (INIS)

    Kolb, E.W.

    1987-01-01

    If the universe stated from conditions of high temperature and density, there should have been a series of phase transitions associated with spontaneous symmetry breaking. The cosmological phase transitions could have observable consequences in the present Universe. Some of the consequences including the formation of topological defects and cosmological inflation are reviewed here. One of the most important tools in building particle physics models is the use of spontaneous symmetry breaking (SSB). The proposal that there are underlying symmetries of nature that are not manifest in the vacuum is a crucial link in the unification of forces. Of particular interest for cosmology is the expectation that are the high temperatures of the big bang symmetries broken today will be restored, and that there are phase transitions to the broken state. The possibility that topological defects will be produced in the transition is the subject of this section. The possibility that the Universe will undergo inflation in a phase transition will be the subject of the next section. Before discussing the creation of topological defects in the phase transition, some general aspects of high-temperature restoration of symmetry and the development of the phase transition will be reviewed. 29 references, 1 figure, 1 table

  10. Regulating the grid-based energies in Central and Eastern Europe: models, status, issues

    International Nuclear Information System (INIS)

    Brendow, K.

    2000-01-01

    As the electricity, gas and heat industries of the economies in transition move towards more market-oriented frameworks, regulators are established to secure fair competition, protection of the customers and a minimum of public service. The paper describes the various models used or contemplated in the autumn of 2000 in central and eastern Europe and identifies fifteen issues, some falling under the competence of governments, others challenging the regulators, again others relating to international co-operation. (author)

  11. Gifts from Exoplanetary Transits

    Science.gov (United States)

    Narita, Norio

    2009-08-01

    The discovery of transiting extrasolar planets has enabled us to do a number of interesting studies. Transit photometry reveals the radius and the orbital inclination of transiting planets, which allows us to learn the true mass and density of the respective planets by the combined information from radial velocity (RV) measurements. In addition, follow-up observations of transiting planets, looking at such things as secondary eclipses, transit timing variations, transmission spectroscopy, and the Rossiter-McLaughlin effect, provide us information about their dayside temperatures, unseen bodies in systems, planetary atmospheres, and the obliquity of planetary orbits. Such observational information, which will provide us a greater understanding of extrasolar planets, is available only for transiting planets. Here, I briefly summarize what we can learn from transiting planets and introduce previous studies.

  12. Parameters' influence estimation on Puf supply and demand in transitional period from LWR to FBR in Japan

    International Nuclear Information System (INIS)

    Kobayashi, Hiroaki; Ohta, Hirokazu; Inoue, Tadashi

    2009-01-01

    Plutonium fissile (Puf) amounts to balance supply and demand during transition period were evaluated with different parameters. Estimated total Puf demand in transitional period was sensitive to deployment speed of FBR. Because FBRs will be deployed as replacements of old LWRs for keeping total capacity, deployment history of existing LWRs should be taken into consideration. According to the estimation, LWR fuel burnup and utilized capacity are not big issue. Because certain amount of LWR spent fuel will remain in early phase of transitional period, there is enough time for preparing Puf supply. On the other hand, FBR fuel cycle time (SF cooling time + fuel fabrication time) have large impact on Puf supply. Fuel cycle technologies including transportation for applying to short cooling spent fuels should be developed. (author)

  13. Which energy transition for France?

    International Nuclear Information System (INIS)

    Criqui, Patrick

    2014-01-01

    While recalling the five main objectives of the French bill project for energy transition, the author proposes some critical reflections. He notices that economic, political and financial means to reach the expected decrease of energy consumption are not sufficient. He notably comments the content of the various retained scenarios, discusses and explains the fact that there will always be a gap between the expected optimal energy efficiency and the obtained results: economic actors are not ready to make the required investments, France lacks of a culture of territorial energy governance, and a way of paying the produced carbon emissions is missing. He discusses the introduction of a carbon tax. He states that the Efficiency scenario seems difficult to be reached and briefly discusses the associated consequences. He finally outlines that the nuclear issue is not clearly addressed, either in the Ademe's scenario or by the bill project

  14. Scheduling and location issues in transforming service fleet vehicles to electric vehicles

    DEFF Research Database (Denmark)

    Mirchandani, Pitu; Madsen, Oli B.G.; Adler, Jonathan

    There is much reason to believe that fleets of service vehicles of many organizations will transform their vehicles that utilize alternative fuels which are more sustainable. The electric vehicle is a good candidate for this transformation, especially which “refuels” by exchanging its spent...... batteries with charged ones. This paper discusses the issues that must be addressed if a transit service were to use electric vehicles, principally the issues related to the limited driving range of each electric vehicle’s set of charged batteries and the possible detouring for battery exchanges....... In particular, the paper addresses the optimization and analysis of infrastructure design alternatives dealing with (1) the number of battery-exchange stations, (2) their locations, (3) the recharging capacity and inventory management of batteries at each facility, and (4) routing and scheduling of the fleet...

  15. The evolution of the electric power grid within the energy transition. Breakfast of 8 February 2017

    International Nuclear Information System (INIS)

    Prins, Katrien; ); Bendtsen, Bendt; ); Derdevet, Michel; Duerr, Matthias; Laffaye, Herve

    2017-01-01

    This document proposes a synthesis of contributions, questions and answers of a meeting gathering French and Danish representatives of political parties, electric utilities and European bodies which addressed issues related to the evolution of the electric power grid within a context of energy transition. Several issues have been addressed. First, the approach adopted by institutional actors like the European Commission and Parliament with a priority given to grid infrastructures to ensure interconnection between all member States, a financial support for the associated investments, and a European governance. Second, the approach adopted by operators in charge of networks, transport and distribution to face a change in the business model, an increasing financial burden, the issue of acceptability of works, future evolutions and innovations, and a closer collaboration

  16. Examination of youth sexual and reproductive health transitions in Nigeria and Kenya using longitudinal data

    Directory of Open Access Journals (Sweden)

    Ilene S. Speizer

    2017-01-01

    Full Text Available Abstract Background The adolescent (ages 15–19 and young adult (ages 20–24 years are a crucial time as many sexual and reproductive health (SRH transitions take place in these years. The study of youth SRH transitions in sub-Saharan Africa is limited due to a paucity of longitudinal data needed to examine the timing and circumstances of these transitions. Methods This paper uses recently collected longitudinal data from select urban areas in Kenya and Nigeria that include a large youth sample at baseline (2010/2011 and endline (2014. We control for unobserved heterogeneity in our modelling approach to correct for selectivity issues that are often ignored in similar types of analyses. Results We demonstrate that the transition patterns (i.e., sexual initiation, first marriage, and first pregnancy/birth differ within and across the urban areas and countries studied. Urban Kenyan youth have more premarital sex and pregnancy than youth from the Nigerian cities. Further analyses demonstrate that more educated and wealthier youth transition later than their less educated and poorer counterparts. Conclusions The findings from this study can be used to inform programs seeking to serve young people based on their varying reproductive health needs in different contexts over the adolescent and young adult years.

  17. Accelerating Energy and Environmental Transition in Europe through digital

    International Nuclear Information System (INIS)

    Reinaud, Julia; Clinckx, Nicolas; Faraggi, Paul

    2017-01-01

    Digitalization is becoming ubiquitous in the energy sector, enabling a more decentralized energy system and blurring the traditional energy sector boundaries, with more integration with buildings, mobility solutions and industry. Digitalization is accelerating the pace of the energy transition, mainly thanks to three levers: 1) enhancing customer interaction with the energy system, 2) optimizing operations, and 3) enabling new business models for traditional energy actors as well as opening up space for new entrants from other sectors and energy start-ups. Digital technologies are also facilitating a cost-effective, clean energy transition, mainly by increasing energy efficiency and flexibility, as well as enabling the integration of renewable electricity into smart(er) grids and developing low-carbon solutions. This article gives a brief overview of the digitally-enabled innovations in Europe's energy markets and how various players are positioning themselves to take advantage of these opportunities. It concludes by highlighting some of the policy issues this transformation raises and the challenges ahead for European businesses to reap the benefits

  18. Transition and worker mobility behaviour of tourism alumni: The case of Switzerland

    OpenAIRE

    Heller, Andreas

    2008-01-01

    The research paper investigates the behaviour of tourism alumni at the transition from tourism education market to tourism labour market and from tourism labour market to other labour markets. The paper focuses especially on the decisions of tourism graduates to enter in the tourism labour market as "stayer" or to exit the tourism industry as "mover". The first part commences with some facts and figures from the hotel and restaurant industry of Switzerland regarding the mover issue. The secon...

  19. Post discharge issues identified by a call-back program: identifying improvement opportunities.

    Science.gov (United States)

    Ojeda, Patricia I; Kara, Areeba

    2017-12-01

    The period following discharge from the hospital is one of heightened vulnerability. Discharge instructions serve as a guide during this transition. Yet, clinicians receive little feedback on the quality of this document that ties into the patients' experience. We reviewed the issues voiced by discharged patients via a call-back program and compared them to the discharge instructions they had received. At our institution, patients receive an automated call forty-eight hours following discharge inquiring about progress. If indicated by the response to the call, they are directed to a nurse who assists with problem solving. We reviewed the nursing documentation of these encounters for a period of nine months. The issues voiced were grouped into five categories: communication, medications, durable medical equipment/therapies, follow up and new or ongoing symptoms. The discharge instructions given to each patient were reviewed. We retrieved data on the number of discharges from each specialty from the hospital over the same period. A total of 592 patients voiced 685 issues. The numbers of patients discharged from medical or surgical services identified as having issues via the call-back line paralleled the proportions discharged from medical and surgical services from the hospital during the same period. Nearly a quarter of the issues discussed had been addressed in the discharge instructions. The most common category of issues was related to communication deficits including missing or incomplete information which made it difficult for the patient to enact or understand the plan of care. Medication prescription related issues were the next most common. Resource barriers and questions surrounding medications were often unaddressed. Post discharge issues affect patients discharged from all services equally. Data from call back programs may provide actionable targets for improvement, identify the inpatient team's 'blind spots' and be used to provide feedback to clinicians.

  20. Status of safety issues at licensed power plants: TMI Action Plan requirements, unresolved safety issues, generic safety issues, other multiplant action issues

    International Nuclear Information System (INIS)

    1992-12-01

    This report is to provide a comprehensive description of the implementation and verification status of Three Mile Island (TMI) Action Plan requirements, safety issues designated as Unresolved Safety Issues (USIs), Generic Safety Issues(GSIs), and other Multiplant Actions (MPAs) that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. An additional purpose of this NUREG report is to serve as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues up until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

  1. Systematic expansion in the order parameter for replica theory of the dynamical glass transition.

    Science.gov (United States)

    Jacquin, Hugo; Zamponi, Francesco

    2013-03-28

    It has been shown recently that predictions from mode-coupling theory for the glass transition of hard-spheres become increasingly bad when dimensionality increases, whereas replica theory predicts a correct scaling. Nevertheless if one focuses on the regime around the dynamical transition in three dimensions, mode-coupling results are far more convincing than replica theory predictions. It seems thus necessary to reconcile the two theoretic approaches in order to obtain a theory that interpolates between low-dimensional, mode-coupling results, and "mean-field" results from replica theory. Even though quantitative results for the dynamical transition issued from replica theory are not accurate in low dimensions, two different approximation schemes--small cage expansion and replicated hyper-netted-chain (RHNC)--provide the correct qualitative picture for the transition, namely, a discontinuous jump of a static order parameter from zero to a finite value. The purpose of this work is to develop a systematic expansion around the RHNC result in powers of the static order parameter, and to calculate the first correction in this expansion. Interestingly, this correction involves the static three-body correlations of the liquid. More importantly, we separately demonstrate that higher order terms in the expansion are quantitatively relevant at the transition, and that the usual mode-coupling kernel, involving two-body direct correlation functions of the liquid, cannot be recovered from static computations.

  2. Transition between nuclear and quark-gluon descriptions of hadrons and light nuclei

    Science.gov (United States)

    Holt, R. J.; Gilman, R.

    2012-08-01

    We provide a perspective on studies aimed at observing the transition between hadronic and quark-gluonic descriptions of reactions involving light nuclei. We begin by summarizing the results for relatively simple reactions such as the pion form factor and the neutral pion transition form factor as well as that for the nucleon and end with exclusive photoreactions in our simplest nuclei. A particular focus will be on reactions involving the deuteron. It is noted that a firm understanding of these issues is essential for unravelling important structure information from processes such as deeply virtual Compton scattering as well as deeply virtual meson production. The connection to exotic phenomena such as color transparency will be discussed. A number of outstanding challenges will require new experiments at modern facilities on the horizon as well as further theoretical developments.

  3. Transit-oriented development: an examination of America's transit precincts in 2000 & 2010.

    Science.gov (United States)

    2013-06-01

    This study creates a typology of all fixed transit precincts across the United States to categorize all stations as either a Transit Oriented Development (TOD), Transit Adjacent Development (TAD) or hybrid. This typology is based on an index that acc...

  4. Les annees de transition: une epoque de changement. Reveu et analyse des projets pilotes sur les questions relatives aux annees de Transition. Volume 1: Resume (Year of Transition: Times for Change. A Review and Analysis of Pilot Projects Investigating Issues in the Transition Years. Volume 1: Summary).

    Science.gov (United States)

    Hargreaves, Andy; And Others

    In 1990, the Ontario (Canada) Ministry of Education implemented the Transition Years project, an initiative for restructuring middle-grades education. This French-language document presents findings of a study that identified effective policies and practices used by the pilot schools. Data were derived from: (1) surveys completed by staffs in…

  5. Decommissioning and reclamation of the Beaverlodge uranium mine-mill operation: current state of the transition phase

    International Nuclear Information System (INIS)

    Phillips, R.L.J.; Himbeault, K.T.; Topp, B.J.; Halbert, B.E.; Fernandes, S.L.

    2000-01-01

    The Beaverlodge uranium mining and milling facilities were operated from 1952 to 1981 with about 94% of the ore extracted from the main underground mine and 6% from smaller satellite deposits. Decommissioning work occurred from 1982 to 1985 involving periods of shutdown, salvage and reclamation. Transition phase monitoring, leading to eventual delicencing commenced in July 1985. Over the last 15 years, discharge from the tailings management facility (TMF) and a fresh water stream, impacted during the operational phase by tailings spills, has improved in water quality for most parameters of concern. Loadings to the environment of three key contaminants (radium-226, total dissolved solids and uranium) have consistently been less than during the operational phase with radium-226 having the greatest variability. Outstanding environmental issues associated with the recovering drainage system formerly used for tailings disposal, are being addressed in an enhanced environmental monitoring program to commence in 2000. Changes in water chemistry and the natural re-introduction of aquatic organisms are issues of concern. In the meantime, application for release from selected satellite areas commenced in 1999. This paper reviews the issues which have arisen during the transition phase, outlines how they have and are being addressed, and provides a comparison of original and current predictions of the recovery process underway at the former Beaverlodge mine site. (author)

  6. Women's Employment Transitions and Changes in Psychological Distress

    Directory of Open Access Journals (Sweden)

    Wilk, Piotr

    2001-01-01

    Full Text Available EnglishThe effect of employment on women's psychological well being has become animportant issue in the sociology of mental health. Although work-for-pay is thought to have an overallpostiive impact on women's psychological well being, not all women equally experience this positiveeffect. The objective of this study is to assess the effect of transitions in employment status onchanges in psychological distress among women in two types of family setting: lone parent families andmarried couple families (including common-law unions. Using a framework which combines a longitudinaldesign with a structural equation modelling multigroup analysis, the current study indicates clearlythat the employment transitions and employment stability have no uniform effect on the mental healthof all mothers. Specifically, transition into employment offers a significant reduction in feelings ofdistress only among married mothers. Single mothers, in contrast are found to experience a significantincrease in the level of distress when they move out of employment. The results of this study point tosome advantages of longitudinal research designs over cross-section designs.FrenchL'effet de l'emploi sur le bien-être psychologique des femmes est devenu unequestion importante en sociologie de santé mentale. Bien que le travail payé aitun impact positif global sur le bien-être psychologique des femmes, pas toutesles femmes éprouvent également cet effet positif. L'objectif de cette étude estd'évaluer l'effet des transitions dans le statut d'emploi sur des changements de ladétresse psychologique parmi des femmes dans deux types de famille: famillesà un seul parent et familles à couple mariés (y compris les mariages de fait. Enutilisant un cadre qui combine une analyse longitudinale avec une équationstructurale modelant plusieurs groupes, l'étude actuelle indique clairement queles transitions d'emploi et la stabilité d'emploi n'ont pas un effet uniforme sur lasant

  7. A Tale of Two Chinese Transit Metropolises and the Implementation of Their Policies: Shenyang and Dalian (Liaoning Province, China)

    NARCIS (Netherlands)

    Mu, R.; de Jong, W.M.

    2018-01-01

    To promote sustainable urbanization and combat the economic, environmental, energy and safety issues that go with rapid motorization, the Ministry of Transport in China has introduced the “Transit Metropolis” program with a substantive amount of funds devoted to the implementation of the program in

  8. Open issues concerning cross border trade mechanism in southeastern European countries

    International Nuclear Information System (INIS)

    Gugu, Florin; Mihailescu, Florentina; Cirlan, Florica

    2004-01-01

    The first South East Europe Electricity Regulatory Forum (SEEER) has agreed that all participants in the 'Athens Process' (AP) should collaborate efficiently in achieving a clear common objective consisting in the creation of a competitive Regional Electricity Market (REM) in South-Eastern Europe (SEE), based on the rules currently in force and being developed in the European Union. The 'Memorandum of Understanding on the REM in SEE and its integration in EU Internal Electricity Market (IEM)' has charged CEER to undertake actions for pursuing a series of specific technical activities. One of the most important actions was the implementation of a trading mechanism such as cross border tariffs. Based on this mechanism the Transmission System Operators, TSO, shall receive compensation for costs incurred as a result of hosting transit flows of electricity on their network. An important problem is the Horizontal Network (HN) cost calculation. Horizontal Network is defined as a part of the transmission network that is most significantly influenced by the cross border exchanges. The calculation of the cost of the SEE HN is in some way problematic because the reorganization of the SEE power sector in different countries is often at the beginning. The paper presents the impact on the TSO's cost claim of the following technical issues which, at present, are not solved in conformity to ETSO CBT mechanism for 2003: - 110 kV network inclusion in the HN definition and its impact on HN cost; - Consideration of the standard cost in the calculation of the HN annual cost; - Consideration of the annual consumption for the calculation of the HN annual cost due to transits (transit key). The Cross Border Trade, CBT, mechanism represents an harmonized payment scheme for the compensation of the national transmission systems for their usage by the cross border flows. The paper addresses the following issues: 1. Assessment of the current state of play in the SEE region; 2. Main principles

  9. Savings serving energy transition Green finance: a powerful and citizen-oriented tool. Working paper no. 11

    International Nuclear Information System (INIS)

    Vergne, Frederique; Kerhoas, Mailys; Lety, Benoit; Lutzky, Ana

    2015-06-01

    The lack of funding is often considered, especially by public decision-makers, as one of the major reasons for the slow-down of implementation of energy transition. However, savings and cash flow have never been so abundant. With exclusive money creation, facilitated by very accommodating monetary policies implemented by central banks, financial markets are over-flown with cash flow. This paradox underlines that the issue is not caused by the lack of financial means but rather on the lack of tools favouring the allocation of such means to energy transition. Investments needs are considerable, ranging from 60 to 70 billion Euros each year, which represents approximately 3% of the European GDP. On the European level, expenses supposed to be dedicated to energy transition are valued around 350 to 400 billion Euros each year during 10 years, or, once again, around 3% of the European GDP. The issue is mainly to allocate investments differently rather than increasing their global volume. Public authorities are not able to manage such investments directly and on their own. However, while private players from the financial sector haven taken initiatives and commitments, these have so far proven insufficient in comparison with the scope of the challenge. It is true that public authorities have often avoided acting directly on financial players. However, finance is not a neutral tool and its players, being part of the economy, have a specific role to play. Beyond the necessary development of local and public funding mechanisms favouring sustainable development projects? Which were not dealt with by the working group? This memo focuses on essential tools to create an efficient mechanism which supports huge allocation of savings on energy transition. Thus, it stresses out a global and innovative proposal with strong potential consequences, involving the implementation and the generalization of an 'energy transition' label for financial products, in order to enable

  10. Transition Dipole Moments and Transition Probabilities of the CN Radical

    Science.gov (United States)

    Yin, Yuan; Shi, Deheng; Sun, Jinfeng; Zhu, Zunlue

    2018-04-01

    This paper studies the transition probabilities of electric dipole transitions between 10 low-lying states of the CN radical. These states are X2Σ+, A2Π, B2Σ+, a4Σ+, b4Π, 14Σ‑, 24Π, 14Δ, 16Σ+, and 16Π. The potential energy curves are calculated using the CASSCF method, which is followed by the icMRCI approach with the Davidson correction. The transition dipole moments between different states are calculated. To improve the accuracy of potential energy curves, core–valence correlation and scalar relativistic corrections, as well as the extrapolation of potential energies to the complete basis set limit are included. The Franck–Condon factors and Einstein coefficients of emissions are calculated. The radiative lifetimes are determined for the vibrational levels of the A2Π, B2Σ+, b4Π, 14Σ‑, 24Π, 14Δ, and 16Π states. According to the transition probabilities and radiative lifetimes, some guidelines for detecting these states spectroscopically are proposed. The spin–orbit coupling effect on the spectroscopic and vibrational properties is evaluated. The splitting energy in the A2Π state is determined to be 50.99 cm‑1, which compares well with the experimental ones. The potential energy curves, transition dipole moments, spectroscopic parameters, and transition probabilities reported in this paper can be considered to be very reliable. The results obtained here can be used as guidelines for detecting these transitions, in particular those that have not been measured in previous experiments or have not been observed in the Sun, comets, stellar atmospheres, dark interstellar clouds, and diffuse interstellar clouds.

  11. Physics of societal issues calculations on national security, environment, and energy

    CERN Document Server

    Hafemeister, David

    2014-01-01

    This book provides the reader with essential tools needed to analyze complex societal issues and demonstrates the transition from physics to modern-day laws and treaties. This second edition features new equation-oriented material and extensive data sets drawing upon current information from experts in their fields. Problems to challenge the reader and extend discussion are presented on three timely issues:   •        National Security: Weapons, Offense, Defense, Verification, Nuclear Proliferation, Terrorism •        Environment: Air/Water, Nuclear, Climate Change, EM Fields/Epidemiology •        Energy: Current Energy Situation, Buildings, Solar Buildings, Renewable  Energy, Enhanced End-Use Efficiency, Transportation, Economics   Praise for the first edition: "This insight is needed in Congress and the Executive Branch. Hafemeister, a former Congressional fellow with wide Washington experience, has written a book for physicists, chemists and engineers who want to learn science...

  12. Assessment of policy issues in nuclear safety regulation according to circumstantial changes

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Soon Heung; Lee, Byong Ho; Baek, Won Pil; Lee, Kwang Gu; Huh, Gyun Young; Hahn, Young Tae [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    2000-03-15

    The objective of the work is to assess various issues in nuclear safety regulation in consideration of circumstantial changes. Emphasis is given to the safety of operating NPPs. It is concluded that the Periodic Safety Review (PSR) should be implemented in Korea as soon as possible, in harmonization with the regulation for life extension of NPPs. The IAEA guidelines, including 10 year intervals and 11 safety factors, should be used as the basic guidelines. The approach to improve regulatory effectiveness is also reviewed and a transition to 'knowledge-based regulation' is suggested.

  13. Transition to Parenthood and Susceptibility to Divorce: qualitative research of divorced young parents in Slovenia

    Directory of Open Access Journals (Sweden)

    Nataša Rijavec Klobučar

    2016-04-01

    Full Text Available Transition to parenthood is a vulnerable period for spouses and can consequently lead to the disintegration of their relationship. The purpose of this research was to examine the experience of this transition, circumstances and risk factors for divorce from the perspective of divorcees in Slovenia who divorced in the first year of their child’s life. On the basis of semi -structured interviews with 15 divorcees, the findings of studies examining changes after the birth of a child were confirmed. The results pointed to risk factors for marriage, such as uncertain relationship between spouses prior to the childbirth, permeable boundaries in relations with families of origin, lack of practical and emotional support, and unreal expectations. The child’s arrival accentuates unsolved issues from the past and brings additional vulnerability to the relationship. The findings of this research are a contribution to the development of preventive, educative and therapeutic programmes for couples in transition to parenthood.

  14. [Care continuity for patients with Prader-Willi syndrome during transition from childhood to adulthood].

    Science.gov (United States)

    Saitoh, Shinji

    2010-01-01

    Prader-Willi syndrome(PWS) is a complex multisystem genetic disorder, of which characteristic phenotypes include neonatal hypotonia, hyperphagia resulting in obesity, mental retardation, hypogonadism, and behavioral and psychiatric problems. The diagnosis can be obtained as early as during neonatal period thanks to development of genetic testing. Clinical features of PWS will change depending on age, although core phenotypes of hyperphagia, obesity and psychiatric issues stay for lifetime. Therefore, integrated multidisciplinary approach starting from neonatal period is mandatory to ensure optimal management to improve lifelong quality of life. For successful transition from childhood to adulthood, multidisciplinary team need to share clinical information, and should keep the same policy about food, environment and psychiatric issues.

  15. Tile Surface Thermocouple Measurement Challenges from the Orbiter Boundary Layer Transition Flight Experiment

    Science.gov (United States)

    Campbell, Charles H.; Berger, Karen; Anderson, Brian

    2012-01-01

    Hypersonic entry flight testing motivated by efforts seeking to characterize boundary layer transition on the Space Shuttle Orbiters have identified challenges in our ability to acquire high quality quantitative surface temperature measurements versus time. Five missions near the end of the Space Shuttle Program implemented a tile surface protuberance as a boundary layer trip together with tile surface thermocouples to capture temperature measurements during entry. Similar engineering implementations of these measurements on Discovery and Endeavor demonstrated unexpected measurement voltage response during the high heating portion of the entry trajectory. An assessment has been performed to characterize possible causes of the issues experienced during STS-119, STS-128, STS-131, STS-133 and STS-134 as well as similar issues encountered during other orbiter entries.

  16. How can we ensure the energy transition? Comment assurer la transition energetique?

    Energy Technology Data Exchange (ETDEWEB)

    Rojey, Alexandre

    2007-07-01

    With a continuously growing energy demand, the present energy model is clearly unsustainable due to the decline of fossil fuel resources and the risks of climate change A transition towards a sustainable model is therefore needed. However, there are no immediate alternatives leading to a sharp reduction in the use of fossil fuels, which are expected to maintain a major role for many years. The energy transition will therefore require a long time period The risks of climate change will require urgent measures and the 'carbon transition' has to be achieved more rapidly than the energy transition itself. A whole set of solutions will be needed in the technical but also economic and regulatory areas, for achieving a successful transition: energy conservation, diversification of energy . sources, reduction of the carbon content of the energy mix, CO{sub 2}, capture and storage. Hybrid options will be favoured. The paper describes the main features of the upcoming transition and the actions which are required. (auth)

  17. Energy transition: gas asserts its assets

    International Nuclear Information System (INIS)

    Passebon, Philippe; Lesquel, Emmanuelle; Leroux, Hugo

    2016-01-01

    Even though it is a fossil energy, gas has a role to play in energy transition as it emits less CO 2 than oil or coal. In this context, it can be used to fill the gaps due to intermittency of some renewable energies, and moreover can also be obtained from organic matter, and then becomes also a renewable source. A set of articles addresses and illustrates these different issues: the development of technologies to exploit methane, the role of substitute for gas, the assets of methane, of natural gas and of biogas, the transformation of electricity into gas in order to easily store energy (notably in the network gas according to the power-to-gas principle), the development of biomass-based methane, the replacement of oil by LNG (liquefied natural gas) in industry and transports (road and sea transport notably)

  18. Transition from 12 months to 18 months cycles at Krsko in a core physics perspective

    International Nuclear Information System (INIS)

    Jensen-Tornehed, J.

    2004-01-01

    Krsko has historically been operating in 12 months cycles with an annual outage for refuelling and maintenance work. Krsko is now in a transition from 12 months to 18 months cycles. Cycle 19, June 2002 - May 2003, was the last 12 month cycle. Cycle 20, June 2003 - September 2004 is a 15 month transition cycle and cycle 21, September 2004 - April 2006 will be the first 18 month cycle. This paper will describe the effects of the transition in a core physics perspective. There are big differences in how to design an 18 month cycle in comparison with a 12 month cycle. The required number of feed assemblies increases, as well as the content of burnable absorbers in the fuel. The strategy of the loading pattern has to be changed with the increased number of fresh fuel assemblies. The most limiting margins can be different for different cycle lengths which also affect the fresh assembly design and loading pattern during the transition. During the core design for cycle 21 the Moderator Temperature Coefficient was the main issue, which caused the need for extra amount of burnable absorbers. (author)

  19. The Chinese initial public offering market : underpricing, duration to listing and hot issue cycles

    OpenAIRE

    Guo, Haifeng

    2017-01-01

    This thesis conducts three empirical studies on the Chinese A-share initial public offering (IPO) market, specifically, underpricing and short-run underperformance, duration from offering to listing and hot and cold issuing cycles. Before the empirical analysis, the literature is reviewed associated with these three topics. In addition, this thesis presents an overview of the Chinese IPO market which is found to undergo an experiment period from 1984 to 1990, a transition period from 1991 to ...

  20. Anti-inflammatory effects of antibacterials on human bronchial epithelial cells

    Directory of Open Access Journals (Sweden)

    Hatz Rudolf

    2009-09-01

    Full Text Available Abstract Background Human Bronchial epithelial cells (hu-BEC have been claimed to play a significant role in the pathogenesis of chronic inflammatory airway diseases like COPD. In this context IL-8 and GM-CSF have been shown to be key cytokines. Some antibiotics which are routinely used to treat lower respiratory tract infections have been shown to exert additional immunomodulatory or anti-inflammatory effects. We investigated whether these effects can also be detected in hu-BEC. Methods Hu-BEC obtained from patients undergoing lung resections were transferred to air-liquid-interface (ALI culture. These cultures were incubated with cefuroxime (CXM, 10-62.5 mg/l, azithromycin (AZM, 0.1-1.5 mg/l, levofloxacin (LVX, 1-8 mg/l and moxifloxacin (MXF, 1-16 mg/l. The spontaneous and TNF-α (10 ng/ml induced expression and release of IL-8 and GM-CSF were measured using PCR and ELISA in the absence or presence of these antibiotics. Results The spontaneous IL-8 and GM-CSF release was significantly reduced with MXF (8 mg/l by 37 ± 20% and 45 ± 31%, respectively (both p Conclusion Using ALI cultures of hu-BEC we observed differential effects of antibiotics on spontaneous and TNF-α induced cytokine release. Our data suggest that MXF and AZM, beyond bactericidal effects, may attenuate the inflammatory process mediated by hu-BEC.

  1. Facility transition instruction

    International Nuclear Information System (INIS)

    Morton, M.R.

    1997-01-01

    The Bechtel Hanford, Inc. facility transition instruction was initiated in response to the need for a common, streamlined process for facility transitions and to capture the knowledge and experience that has accumulated over the last few years. The instruction serves as an educational resource and defines the process for transitioning facilities to long-term surveillance and maintenance (S and M). Generally, these facilities do not have identified operations missions and must be transitioned from operational status to a safe and stable configuration for long-term S and M. The instruction can be applied to a wide range of facilities--from process canyon complexes like the Plutonium Uranium Extraction Facility or B Plant, to stand-alone, lower hazard facilities like the 242B/BL facility. The facility transition process is implemented (under the direction of the US Department of Energy, Richland Operations Office [RL] Assistant Manager-Environmental) by Bechtel Hanford, Inc. management, with input and interaction with the appropriate RL division and Hanford site contractors as noted in the instruction. The application of the steps identified herein and the early participation of all organizations involved are expected to provide a cost-effective, safe, and smooth transition from operational status to deactivation and S and M for a wide range of Hanford Site facilities

  2. QCD phase transition in the laboratory and in the early universe

    International Nuclear Information System (INIS)

    Sinha, Bikash

    1998-01-01

    It is expected that two nuclei colliding at ultra-relativistic energies (∼ 200 GeV/nucleon or more) may lead to hadronic matter go through a phase transition to its fundamental constituents, quarks and gluons, usually referred to as quark gluon plasma (QGP). Somewhat analogously, the universe, as per conventional wisdom should have consisted of quarks, gluons, leptons and photons, a microsecond after the Big Bang. The experience and wisdom, expected from nucleus-nucleus collisions in the laboratory and anticipated to facilitate our understanding of the quark-hadron phase transition. Indeed what possible footprints of that primordial epoch can be traced in today's cosmos is one of the interesting and intriguing questions. In this paper, the following areas will be focused: the issue of successive thermal and chemical equilibrium scenarios; a detailed study of hot hadronic matter and its implication on the thermal model; and finally, the surviving quark nuggets beyond a critical baryon content, and, nuggets being possible candidates for baryonic dark matter in the universe, a much more straightforward candidate than illusive actions or SUSY particles. It is our considered view that quark hadron phase transition in the microsecond universe is a thriving area of research and lot more can be understood and known from this primordial event. (author)

  3. Online transit trip planner for small agencies using Google Transit : final deployment package.

    Science.gov (United States)

    2011-09-01

    Google Transit is a public transportation trip planner that enables travelers to obtain information regarding available transit services between a : given origin and given destination. While transit agencies can publish their service information onto...

  4. Caltrans : transit funding manual : managing the delivery of transit projects

    Science.gov (United States)

    2001-05-01

    This manual attempts to provide a step by step transit funding process. Included in this manual : is an overview of Caltrans Division of Mass Transportation, roles and responsibilities in : assisting local agencies to deliver transit projects. Transi...

  5. [Transition - how adolescents with cystic fibrosis their parents experience the change from paediatric to adult care].

    Science.gov (United States)

    Becher, Christine; Regamey, Nicolas; Spichiger, Elisabeth

    2014-12-01

    Cystic Fibrosis is the most common autosomal-recessive hereditary disease among white Europeans. The average survival of CF patients has increased to above 40 years and transition from paediatric to adult care has therefore become a significant issue. With this study, experiences of adolescents with CF and their parents with the transition from the paediatric to the adult care were explored. At a Swiss university CF centre, six adolescents and their mothers were recruited. Twelve narrative interviews were conducted on how the phase of transition was experienced. The transcribed interviews were analysed according to the method of hermeneutic phenomenology. Positive and negative experiences with long term routine care in the paediatric service, general themes of adolescence and the quality of the relationship with paediatric doctors influenced the families' experience during transition significantly. For mothers, insensitive information on the CF diagnosis might have influenced the transition experience. The adolescents welcomed an individualized and age appropriate care. Continuity in care, the announcement of, and involvement in the planning of the transfer were of great importance. The families particularly appreciated the timed adaptations of the transfer to individual needs. Flexibility and a strong collaboration between paediatric and adult CF teams are most relevant in the care of families.

  6. ENVIRONMENTAL INNOVATIVE BUSINESS SOLUTIONS AS A STRATEGIC FACTOR OF ECONOMIC SECURITY ISSUES

    Directory of Open Access Journals (Sweden)

    A. S. Senin

    2016-01-01

    Full Text Available The relevance of this work lies in the fact that it attempts to disclose the key theoretical and practical issues of economic security solutions, taking into account the problems of global transformations taking place in the global economy. As part of the article we have been studied various aspects that characterize global economic, environmental trends that will shape the future of modern civilization. The article also addresses the problem of exit from the raw model of the economy, the formation of economic mechanisms that take into account environmental costs, proposed internalization of environmental externalities.The purpose/goal. The purpose of this article and its main task is to systematize the areas of environmentally oriented development of economic entities, as well as the determination of the list of key provisions of environmental policies, which will ensure the further socio-economic development of Russia in line with the green economy.Methods. In this article, based on content analysis of theoretical and empirical basic conceptual provisions of economic security were formulated in the context of eco-oriented production, the transition to which world civilization is currently implementing. It was concluded that the economic, energy, environmental and social issues of sustainable development of modern civilization is directly linked, so the transition to ecooriented production is possible, firstly, it provided aggressive reduction of production and wasteful use of traditional hydrocarbon resources, and, secondly, on the condition of rational replacement of traditional energy sources with renewable energy.Results. This article outlines the basic solutions that can be used to provide environmentally responsible operation and development of Russian business and corporate structures. Also offered in the basic decisions that are to be included in the national environmental policy as a major incentive for the further transition to a

  7. Transit labor relations guide

    Science.gov (United States)

    2001-09-01

    This report is designed as a guide for those involved in labor relations in the transit industry. It begins with a history of transit labor relations. The economic, political, and legal environment of transit relations is then discussed. A section fo...

  8. Public Transit Stations

    Data.gov (United States)

    Department of Homeland Security — fixed rail transit stations within the Continental United States, Alaska, Hawaii, the District of Columbia, and Puerto Rico. The modes of transit that are serviced...

  9. Gardner Transition in Physical Dimensions

    Science.gov (United States)

    Hicks, C. L.; Wheatley, M. J.; Godfrey, M. J.; Moore, M. A.

    2018-06-01

    The Gardner transition is the transition that at mean-field level separates a stable glass phase from a marginally stable phase. This transition has similarities with the de Almeida-Thouless transition of spin glasses. We have studied a well-understood problem, that of disks moving in a narrow channel, which shows many features usually associated with the Gardner transition. We show that some of these features are artifacts that arise when a disk escapes its local cage during the quench to higher densities. There is evidence that the Gardner transition becomes an avoided transition, in that the correlation length becomes quite large, of order 15 particle diameters, even in our quasi-one-dimensional system.

  10. Transitions across place and space – Spatial transitions in an Actor Network perspective

    DEFF Research Database (Denmark)

    Kerndrup, Søren; Mosgaard, Mette

    2012-01-01

    , that interactions and relations in these networks in spite of their focus on proximity, locality and regional development are integrated in multiple scalar interactions. These multiscalar interactions and relations are mediated by objects and artefacts, and therefore they are often not seen as part of the networks.......The empirical and theoretical frameworks of transitions focus mainly on specific scale of change e.g. local, regional or national transitions. One reason for this lack of an integrative framework of territorial and spatial distribution of transitions process is the ambition of transition framework...... network perspective in order to develop the spatial dimensions of transitions. The paper is based on an ongoing research project of spatial dimensions of the transitions in energy production and consumption networks in the northern part of Denmark. The paper show by using an actor network perspective...

  11. Transitional Leadership: Leadership During Times of Transition, Key Principles, and Considerations for Success.

    Science.gov (United States)

    Norbash, Alexander

    2017-06-01

    To suggest a methodical approach for refining transitional management abilities, including empowerment of a growing leader, leading in an unfamiliar organization or leading in an organization that is changing. Management approaches based on the body of work dealing with leadership studies and transitions and dealing with leadership during times of transition and change management were consolidated and categorized. Transitional leaders can benefit from effective leadership training including defining and prospectively accruing necessary experiences and skills; strengthening information gathering skills; effectively self-assessing; valuing and implementing mentoring; formulating strategy; and communicating. A categorical approach to transitional leadership may be implemented through a systems-based and methodical approach to gaining the definable, and distinct sets of skills and abilities necessary for transitional leadership success. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  12. Transitions and transition management. The case of an emission-low energy supply

    International Nuclear Information System (INIS)

    Rotmans, J.; Van Asselt, M.; Molendijk, K.; Kemp, R.; Geels, F.; Verbong, G.

    2000-12-01

    Transitions are societal transformation processes that occur in at least one generation (i.e. 25 years). Transitions are structural changes of the society or a complex part of that society. Transitions show technological, economical, ecological, socio-cultural and institutional developments on different levels. A transition is the result of slow changes (developments in supplies) and fast dynamics (flows). In general, four transition phases can be distinguished: (1) a pre-development phase of dynamic equilibrium in which the status quo does not change much; (2) a take-off phase in which the process of change is started; (3) an acceleration phase in which structural changes occur, resulting in collective learning processes, diffusion and processes of implementation; (4) a stabilization phase in which the speed of societal changes decreases and a new dynamic equilibrium exists. Within the framework of the preparatory process of the Fourth Dutch National Environmental Plan (NMP4) a study has been carried out to explore the transition concept, focusing on an emission-low energy supply in the Netherlands. 49 refs

  13. System-level Analysis of Food Moisture Content Requirements for the Mars Dual Lander Transit Mission

    Science.gov (United States)

    Levri, Julie A.; Perchonok, Michele H.

    2004-01-01

    In order to ensure that adequate water resources are available during a mission, any net water loss from the habitat must be balanced with an equivalent amount of required makeup water. Makeup water may come from a variety of sources, including water in shipped tanks, water stored in prepackaged food, product water from fuel cells, and in-situ water resources. This paper specifically addresses the issue of storing required makeup water in prepackaged food versus storing the water in shipped tanks for the Mars Dual Lander Transit Mission, one of the Advanced Life Support Reference Missions. In this paper, water mass balances have been performed for the Dual Lander Transit Mission, to determine the necessary requirement of makeup water under nominal operation (i.e. no consideration of contingency needs), on a daily basis. Contingency issues are briefly discussed with respect to impacts on makeup water storage (shipped tanks versus storage in prepackaged food). The Dual Lander Transit Mission was selected for study because it has been considered by the Johnson Space Center Exploration Office in enough detail to define a reasonable set of scenario options for nominal system operation and contingencies. This study also illustrates the concept that there are multiple, reasonable life support system scenarios for any one particular mission. Thus, the need for a particular commodity can depend upon many variables in the system. In this study, we examine the need for makeup water as it depends upon the configuration of the rest of the life support system.

  14. Transitions to Sustainable Development. New Directions in the Study of Long Term Transformative Change

    International Nuclear Information System (INIS)

    Grin, J.; Rotmans, J.; Schot, J.; Geels, F.; Loorbach, D.

    2010-01-01

    Over the past few decades, there has been a growing concern about the social and environmental risks which have come along with the progress achieved through a variety of mutually intertwined modernization processes. In recent years these concerns are transformed into a widely-shared sense of urgency, partly due to events such as the various pandemics threatening livestock, and increasing awareness of the risks and realities of climate change, and the energy and food crises. This sense of urgency includes an awareness that our entire social system is in need of fundamental transformation. But like the earlier transition between the 1750s and 1890s from a pre-modern to a modern industrial society, this second transition is also a contested one. Sustainable development is only one of many options. This book addresses the issue on how to understand the dynamics and governance of the second transition dynamics in order to ensure sustainable development. It will be necessary reading for students and scholars with an interest in sustainable development and long-term transformative change.

  15. Transitions to Sustainable Development. New Directions in the Study of Long Term Transformative Change

    Energy Technology Data Exchange (ETDEWEB)

    Grin, J. [Department of Political Science, University of Amsterdam, Amsterdam (Netherlands); Rotmans, J. [Sustainability Transitions and Transition Management, Erasmus University Rotterdam, Rotterdam (Netherlands); Schot, J. [Eindhoven University of Technology, Eindhoven (Netherlands); Geels, F. [Science Policy Research Unit SPRU, University of Sussex, Brighton (United Kingdom); Loorbach, D. [Dutch Research Institute for Transitions Drift, Erasmus University Rotterdam, Rotterdam (Netherlands)

    2010-07-01

    Over the past few decades, there has been a growing concern about the social and environmental risks which have come along with the progress achieved through a variety of mutually intertwined modernization processes. In recent years these concerns are transformed into a widely-shared sense of urgency, partly due to events such as the various pandemics threatening livestock, and increasing awareness of the risks and realities of climate change, and the energy and food crises. This sense of urgency includes an awareness that our entire social system is in need of fundamental transformation. But like the earlier transition between the 1750s and 1890s from a pre-modern to a modern industrial society, this second transition is also a contested one. Sustainable development is only one of many options. This book addresses the issue on how to understand the dynamics and governance of the second transition dynamics in order to ensure sustainable development. It will be necessary reading for students and scholars with an interest in sustainable development and long-term transformative change.

  16. Energy Transitions towards Sustainability I: A Staged Exploration of Complexity and Deep Uncertainty

    OpenAIRE

    Pruyt, E.; Kwakkel, J.; Yucel, G.; Hamarat, C.

    2011-01-01

    This paper illustrates the use of Exploratory System Dynamics Modeling and Analysis – a multi-method combining System Dynamics and Exploratory Modeling and Analysis to explore and analyze uncertain dynamic issues and test deep policy robustness. This paper gives an overview of the current state of this multi-method by means of an illustration. The multimethod is applied to the transition of the electricity generation system, more specifically the battle between old and new electricity generat...

  17. Bulletin 2005-12 : revised Alberta pipeline regulation issued

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-31

    A revised Pipeline Regulation has been issued and is currently available on the Alberta Energy and Utilities Board (EUB) website. Changes to the regulation reflect bothchanges in EUB regulatory policy and processes and technological improvements. Goals of the revision include improvements in overall pipeline performance, and the implementation of recommendations derived from the Public Safety and Sour Gas Committee concerning sour gas pipeline safety. The regulation was re-organized for greater clarity, and structured into 11 parts. Issues concerning the transition to the revised regulation were presented. The summary of notable administrative changes included clarifications of when a pipeline application is not required; when ABSA approval is required for steam lines; situations for which low-pressure natural gas lines must be licensed; and emergency response requirements. Technical clarifications include requirements for pipeline operations and maintenance manuals; composite materials; limitations on amounts of H{sub 2}S in polymeric pipe; pressure mismatches; approval for testing with gaseous media; venting of small volumes of raw gas; right-of-way surveillance; inspection of surface construction activities; annual corrosion evaluations; registering of pipelines and excavators in controlled areas with Alberta One-Call; ground disturbance training; restoration and signage maintenance on abandoned pipelines; sour service steel pipelines; unused pipelines and abandoned pipelines; and remediation of stub ends in operating pipelines.

  18. Report on energy transition measured against innovation and decentralisation - National Assembly No. 1352 / Senate No. 838

    International Nuclear Information System (INIS)

    Sido, Bruno; Le Deaut, Jean-Yves

    2013-01-01

    In its first part, this report analyses the effort-sharing for energy transition: legal and natural persons have different behaviours and expectations; the required funding is a burden for the economy; non-conventional hydrocarbons could be a possibility but this issue is highly uncertain. The second part addresses the support to innovation processes associated with energy transition: identification of deadlock points, identification of conditions to maintain innovation dynamics. The third part addresses the key role of local initiatives: overview and characteristics of local initiatives, impact on the energy system organization (relationship with smart grids, development of heat networks, and the technological challenge of energy storage). Several texts (hearings, speeches, debates) are provided in appendix

  19. First-order metal-insulator transitions in the extended Hubbard model due to self-consistent screening of the effective interaction

    Science.gov (United States)

    Schüler, M.; van Loon, E. G. C. P.; Katsnelson, M. I.; Wehling, T. O.

    2018-04-01

    While the Hubbard model is the standard model to study Mott metal-insulator transitions, it is still unclear to what extent it can describe metal-insulator transitions in real solids, where nonlocal Coulomb interactions are always present. By using a variational principle, we clarify this issue for short- and long-range nonlocal Coulomb interactions for half-filled systems on bipartite lattices. We find that repulsive nonlocal interactions generally stabilize the Fermi-liquid regime. The metal-insulator phase boundary is shifted to larger interaction strengths to leading order linearly with nonlocal interactions. Importantly, nonlocal interactions can raise the order of the metal-insulator transition. We present a detailed analysis of how the dimension and geometry of the lattice as well as the temperature determine the critical nonlocal interaction leading to a first-order transition: for systems in more than two dimensions with nonzero density of states at the Fermi energy the critical nonlocal interaction is arbitrarily small; otherwise, it is finite.

  20. Cyclotron transitions of bound ions

    Science.gov (United States)

    Bezchastnov, Victor G.; Pavlov, George G.

    2017-06-01

    A charged particle in a magnetic field possesses discrete energy levels associated with particle rotation around the field lines. The radiative transitions between these levels are the well-known cyclotron transitions. We show that a bound complex of particles with a nonzero net charge displays analogous transitions between the states of confined motion of the entire complex in the field. The latter bound-ion cyclotron transitions are affected by a coupling between the collective and internal motions of the complex and, as a result, differ from the transitions of a "reference" bare ion with the same mass and charge. We analyze the cyclotron transitions for complex ions by including the coupling within a rigorous quantum approach. Particular attention is paid to comparison of the transition energies and oscillator strengths to those of the bare ion. Selection rules based on integrals of collective motion are derived for the bound-ion cyclotron transitions analytically, and the perturbation and coupled-channel approaches are developed to study the transitions quantitatively. Representative examples are considered and discussed for positive and negative atomic and cluster ions.

  1. Vulnerability Analysis of Urban Rail Transit Networks: A Case Study of Shanghai, China

    Directory of Open Access Journals (Sweden)

    Daniel (Jian Sun

    2015-05-01

    Full Text Available Rail transit is developing rapidly in major cities of China and has become a key component of urban transport. Nevertheless, the security and reliability in operation are significant issues that cannot be neglected. In this paper, the network and station vulnerabilities of the urban rail transit system were analyzed based on complex network and graph theories. A vulnerability evaluation model was proposed by accounting metro interchange and passenger flow and further validated by a case study of Shanghai Metro with full-scale network and real-world traffic data. It is identified that the urban rail transit network is rather robust to random attacks, but is vulnerable to the largest degree node-based attacks and the highest betweenness node-based attacks. Metro stations with a large node degree are more important in maintaining the network size, while stations with a high node betweenness are critical to network efficiency and origin-destination (OD connectivity. The most crucial stations in maintaining network serviceability do not necessarily have the highest passenger throughput or the largest structural connectivity. A comprehensive evaluation model as proposed is therefore essential to assess station vulnerability, so that attention can be placed on appropriate nodes within the metro system. The findings of this research are of both theoretical and practical significance for urban rail transit network design and performance evaluation.

  2. Curriculum on the European Policy Agenda: Global Transitions and Learning Outcomes from Transnational and National Points of View

    Science.gov (United States)

    Sivesind, Kirsten; Wahlström, Ninni

    2016-01-01

    This special issue examines curricula and their histories as they have evolved throughout the 21st century as part of transnational and national education policies. With a specific focus on the policy transitions that are taking place in Europe, the articles demonstrate how curriculum making processes move in different directions, following their…

  3. How the First Year of College Influences Moral Reasoning Development for Students in Moral Consolidation and Moral Transition

    Science.gov (United States)

    Mayhew, Matthew J.; Seifert, Tricia A.; Pascarella, Ernest T.

    2012-01-01

    Understanding the developmental issues first-time college students face is critical for scholars and educators interested in learning and development. This purpose of this study was to investigate the differential impact of first-year college experiences on the moral reasoning development of 1,469 students in moral transition versus those in moral…

  4. Institutions, Sustainability Transitions and Aspects of Internationalisation

    DEFF Research Database (Denmark)

    Decker, Arnim

    The shift towards economic activities that are environmentally sustain- able involves the need to overcome incumbent socio- technical regimes that are environmentally unsustainable but difficult to replace. Techno- logical and institutional co-evolution of practices and technologies with large...... scale effects and strong path dependencies create significant obsta- cles that stand in the way to adapting technologies that cause less or no damage to the environment. This phenomenon has been termed "carbon lock-in" (Unruh, 2002), it impedes the introduction of environmentally friendly practices...... and technologies or makes it an uphill struggle. Until recently, most existing studies have taken single national systems as units of analysis while issues of internationalization are just emerging on the agenda. With a high degree of uncertainty involved, becoming part of a sustainability transition is a risky...

  5. The electricity market in transition: a decoding

    International Nuclear Information System (INIS)

    Mathieu, Mathilde; Schwarz, Virginie; Chapon, Antoine; Fouquet, Doerte; Joos, Marine; Jedliczka, Marc; Siess, Damien

    2015-01-01

    A set of article proposes a discussion of the main challenges for energy transition for the architecture of the European electricity market, an interview of the responsible of the energy department within the French ministry of ecology (she addresses the issues of market, electricity system, renewable energies), a discussion of the first lessons learned from the integration of renewable energies in the electricity market, a comment on hazardous evolutions for independent producers, a discussion of the pilot stage for bidding in Germany, a discussion of false ideas and true challenges in the relationship between demand management and integration, a comment on the evolution towards a complete reform of the support system for renewable energies, and a discussion of the perspectives beyond 40 per cent of renewable energies in the French electricity mix

  6. Modeling for transition management

    NARCIS (Netherlands)

    Chappin, E.J.L.; Dijkema, G.P.J.

    2015-01-01

    A framework for the modeling and simulation of transitions is presented. A transition, “substantial change in the state of a socio-technical system”, typically unfolds over a long timespan. We therefore suggest to use simulation to inform transition managers on the effect of their decisions.

  7. Modeling for Transition Management

    NARCIS (Netherlands)

    Chappin, Emile J L; Dijkema, Gerard P.J.

    2015-01-01

    A framework for the modeling and simulation of transitions is presented. A transition, “substantial change in the state of a socio-technical system”, typically unfolds over a long timespan. We therefore suggest to use simulation to inform transition managers on the effect of their decisions.

  8. Workers in transition

    OpenAIRE

    Rutkowski, Michael

    1995-01-01

    After Central and Eastern European and Central Asian economies abandoned central planning, nearly 195 million workers had to adjust to new rules of work and life. Most transition economies have not yet fully committed themselves to the rules of the market place. A few that have are already enjoying growth in wages and employment; in other countries, labor income growth is still to come. Reform has not been so well accepted in countries that were forced to enter the transition. Transition brou...

  9. K-forbidden transition probabilities

    International Nuclear Information System (INIS)

    Saitoh, T.R.; Sletten, G.; Bark, R.A.; Hagemann, G.B.; Herskind, B.; Saitoh-Hashimoto, N.; Tsukuba Univ., Ibaraki

    2000-01-01

    Reduced hindrance factors of K-forbidden transitions are compiled for nuclei with A∝180 where γ-vibrational states are observed. Correlations between these reduced hindrance factors and Coriolis forces, statistical level mixing and γ-softness have been studied. It is demonstrated that the K-forbidden transition probabilities are related to γ-softness. The decay of the high-K bandheads has been studied by means of the two-state mixing, which would be induced by the γ-softness, with the use of a number of K-forbidden transitions compiled in the present work, where high-K bandheads are depopulated by both E2 and ΔI=1 transitions. The validity of the two-state mixing scheme has been examined by using the proposed identity of the B(M1)/B(E2) ratios of transitions depopulating high-K bandheads and levels of low-K bands. A break down of the identity might indicate that other levels would mediate transitions between high- and low-K states. (orig.)

  10. Deflagration-to-detonation transition in gases in tubes with cavities

    Science.gov (United States)

    Smirnov, N. N.; Nikitin, V. F.; Phylippov, Yu. G.

    2010-12-01

    The existence of a supersonic second combustion mode — detonation — discovered by Mallard and Le Chatelier and by Berthélot and Vieille in 1881 posed the question of mechanisms for transition from one mode to the other. In the period 1959-1969, experiments by Salamandra, Soloukhin, Oppenheim, and their coworkers provided insights into this complex phenomenon. Since then, among all the phenomena related to combustion processes, deflagration-to-detonation transition is, undoubtedly, the most intriguing one. Deflagration-to-detonation transition (DDT) in gases is connected with gas and vapor explosion safety issues. Knowing mechanisms of detonation onset control is of major importance for creating effective mitigation measures addressing two major goals: to prevent DDT in the case of mixture ignition, or to arrest the detonation wave in the case where it has been initiated. A new impetus to the increase in interest in deflagration-to-detonation transition processes was given by the recent development of pulse detonation devices. The probable application of these principles to creation of a new generation of engines put the problem of effectiveness of pulse detonating devices at the top of current research needs. The effectiveness of the pulse detonation cycle turned out to be the key factor characterizing the Pulse Detonation Engine (PDE), whose operation modes were shown to be closely related to periodical onset and degeneration of a detonation wave. Those unsteady-state regimes should be self-sustained to guarantee a reliable operation of devices using the detonation mode of burning fuels as a constitutive part of their working cycle. Thus deflagration-to-detonation transition processes are of major importance for the issue. Minimizing the predetonation length and ensuring stability of the onset of detonation enable one to increase the effectiveness of a PDE. The DDT turned out to be the key factor characterizing the PDE operating cycle. Thus, the problem of

  11. Transition to turbulence

    International Nuclear Information System (INIS)

    Pomeau, Y.

    1981-07-01

    In this work it is reviewed a few known types of transition to turbulence, as the cascade of period doubling and the intermittent transition. This happens in dynamical systems with a few degrees of freedom, as modelled by the iteration of non linear maps. Then it is presented specific transitions for systems with many degrees of freedom. It is condidered first the occurence of a low frequency broadband noise in large cells at the onset of Rayleigh-Benard convection; then the transition by intermittent bursts in parallel flows. In this last case, one is concerned with localized and finite amplitude perturbations. Simple geometric arguments show that these fluctuations, when they are isolated and with a well definite relative speed, exist for a single value of the Reynolds number only [fr

  12. A Tale of Two Chinese Transit Metropolises and the Implementation of Their Policies: Shenyang and Dalian (Liaoning Province, China

    Directory of Open Access Journals (Sweden)

    Rui Mu

    2018-02-01

    Full Text Available To promote sustainable urbanization and combat the economic, environmental, energy and safety issues that go with rapid motorization, the Ministry of Transport in China has introduced the “Transit Metropolis” program with a substantive amount of funds devoted to the implementation of the program in local governments. This represents the largest ever central government-led effort addressing transit metropolis development in the world. How has the program been implemented locally? Have the selected demonstration cities followed the same principle or taken comparable measures to implement their version of the transit metropolis? What is their performance? These questions remain unknown in the current literature. This article answers the above questions through a literature review, interviews and comparative case studies in Shenyang and Dalian, two large cities in Liaoning Province. It shows that both cities have successfully achieved the target levels for building a transit metropolis. Similarities between the two cities can be found their absence of any policies on automobile restriction and the presence of enormous efforts in transit network expansion and optimization. Differences lie in the fact that Shenyang has been more conventional in developing the transit metropolis, while Dalian has been more innovative and flexible in policy implementation. When comparing our empirical findings with the experience of creating transit metropolis elsewhere in China and in foreign countries, we find that policies and regulations restricting car use and calming traffic are not necessary conditions for successful transit metropolises; however, the attractiveness of transit infrastructure, combined with aesthetic and well-decorated street network is essential for a modal shift for transit. We also find that the perception on the transit metropolis in China more emphasizes transit service improvement, while the concept in Western countries more focuses on

  13. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2008-10-01

    This report provides preliminary results from a National Renewable Energy Laboratory evaluation of a protoptye fuel cell transit bus operating at Connecticut Transit in Hartford. Included are descriptions of the planned fuel cell bus demonstration and equipment; early results and agency experience are also provided.

  14. Turkey’s Epidemiological and Demographic Transitions: 1931-2013

    Directory of Open Access Journals (Sweden)

    Coşkun Bakar

    2017-08-01

    Full Text Available Background: The causes of death have changed with regard to the epidemiological and demographic events in society. There is no evidence of prior research into the epidemiological transition in Turkey. This transition in Turkey should be observed starting with the Ottoman Empire period (19th to early 20th century. However, information about the Ottoman Empire is quite limited. Aims: To discuss the epidemiological and demographic transitions in Turkey, using demographic, educational and urbanization data in our present study. Study Design: A descriptive archive study. Methods: Mortality statistics dating from 1931 and published by the Turkish Statistical Institute were analysed, and the causes of death were coded and classified according to ICD-10. Other data were obtained from the published reports and studies regarding the issue. Results: In the 1930s, Turkey’s life expectancy was low (aged 40 years, fertility and mortality rates were high (respectively 45% and 31%, and the main causes of death were infectious diseases. Nowadays, life expectancy is close to 80 years, the total fertility rate has dropped to 2.1 per woman, and the main causes of death are chronic diseases and cancer. The population rate in the urban areas has increased steadily from 24.2% in 1927 to 77.3% in 2012. level of education has also increased during this period. In 1935, less than 10% of women were literate, and in 2013 90% were literate. Qualitative and quantitative increase have been observed in the presentation and access of healthcare services compared to the early years of the Republic. Conclusion: Turkey has been undergoing a modernization period in the last 200 years, and it is believed that the epidemiological and demographic transitions result from this period. This process has led to urbanization and an increase in the level of education, as well as a decrease in premature deaths, lower fertility rates, and an increase in the elderly population and chronic

  15. Global Issues

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, J.L.

    2001-10-15

    Global Issues is an introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. This new edition of this text has been fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. Fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. An introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. Covers a range of perspectives on a variety of societies, developed and developing. Extensively illustrated with diagrams and photographs, contains guides to further reading, media, and internet resources, and includes suggestions for discussion and studying the material. (author)

  16. Transition-Systems, Event Structures, and Unfoldings

    DEFF Research Database (Denmark)

    Nielsen, Mogens; Rozenberg, Grzegorz; Thiagarajan, P.S.

    1995-01-01

    systems. Here we show that by smoothly strengthening the regional axioms for elementary transition systems, one obtains a subclass called occurrence transition system. We then prove that occurrence transition systems are the transition system model of yet another basic model of concurrency, namely, prime......A subclass of transition systems called elementary transition systems can be identified with the help of axioms based on a structural notion called regions. Elementary transition systems have been shown to be the transition system model of a basic system model of net theory called elementary net...

  17. Innovation policy for the Dutch energy transition Operationalising transition management?

    NARCIS (Netherlands)

    D.A. Loorbach (Derk); R. Kemp (René)

    2005-01-01

    textabstractThe term transition is a key term of the fourth national environmental policy plan (NMP4, 2001), which put forward transition management (Rotmans et al, 2000) as a new policy approach for dealing with persistent and highly complex societal problems such as climate change, loss of

  18. The transportation issue management system: A tool for issue resolution

    International Nuclear Information System (INIS)

    Branch, K.M.; Boryczka, M.K.

    1987-01-01

    During the last decade, issue management programs have been developed and used by a number of large corporations in the United States. These systems have generally been designed to help senior program managers identify issues, develop strategic plans, and resolve issues. These systems involve scanning and abstracting literature to create a database that is then used for 1) issue identification, 2) issue analysis, 3) priority assessment, 4) development of corporate position/strategic options, and 5) action planning and implementation. Most of the existing systems rely on staff to identify trends in the computerized output, analyze the importance of the issue to the company, and assist in developing corporate responses. The Department of Energy has recently developed an issue management system for the Office of Civilian Radioactive Waste Management's (OCRWM) transportation program. This system is designed to help DOE identify institutional issues related to radioactive waste transportation, analyze the issues, and resolve them in a manner that is responsive to interested parties. The system will contain pertinent information from DOE technical reports, other federal documents, correspondence, professional journals, popular literature, newsclips, legislation and testimony. The program is designed around a number of institutional issues including: prenotification, physical protection procedures; highway, rail, and barge routing; inspections and enforcement of shipments; emergency response; liability, cask design and testing; overweight trucks; rail service; modal mix; infrastructure improvements; training standards, and operational procedures

  19. Information report on the behalf of the Delegation for overseas territories on the bill project nr 2188 related to energy transition for a green growth - Nr 2197

    International Nuclear Information System (INIS)

    Letchimy, Serge

    2014-01-01

    This report first outlines and discusses that energy transition is a necessity as well as an opportunity for overseas local communities for the emergence of a new model of economic development. The potential of these territories in terms of renewable energies is outlined, as well as the important issues for a successful energy transition. The second part comments the implications for the overseas territories of the bill project on energy transition for a green growth (general presentation of the bill project, advances for overseas territories, measures of interest, measures to be deepened)

  20. Here we go again: the january 2007 transit crisis between russia and Belarus

    International Nuclear Information System (INIS)

    Laszlo, Varro

    2007-01-01

    In January 2007 Russia interrupted oil deliveries in the Druzhba (Friendship) pipeline due to a transit dispute with Belarus. Although the issue was resolved quickly and existing commercial and strategic stockpiles proved adequate, the episode had the potential to develop into a serious energy security crisis. The crux of the problem was the allocation of rents generated by Russia's oil export tax system. Because of the customs union between the two countries, this created an artificially high profitability for re- exports of oil products from Belarus. Although Belarus is generally regarded as a political ally of Russia and certainly lacks the western orientation of Ukraine's orange revolution, the accumulating transit and rent sharing revenues became sufficient to trigger a forceful action from Russia. The main significance of the Belarus episode is that it highlighted the energy security risks associated with excessive reliance of a single pipeline system. It also dispelled any hope that the January 2006 Ukraine gas crisis was a once off event. Consequently both Russia and the importing regions are expected to raise their priorities in diversifying transit routes and sources. (author)