Sameer L Pradhan
Full Text Available The use of herbal medicines has increased dramatically over the past few years. The United States alone noted a 380% increase in the consumption of these products. Although the common practice of taking over-the-counter herbal soups, herbal teas and other such prepacked preparations was not associated with adverse events at large, still, some herbs are known to cause problems, especially when large doses are taken. The American Society of Anaesthesiologist (ASA has taken a conservative stance and recommended that it is prudent to stop these products at least 2-3 weeks prior to anaesthesia and surgery. This advice may be difficult to implement as most preoperative evaluations occur only a few days prior to surgery. Some of the Ayurvedic preparations have shown to improve the patient outcome when taken during the perioperative period. Hence, the conservative stance by ASA may not always benefit the patient. More scientific studies are needed to have more targeted recommendations. This article puts forward the facts that need to be addressed by researchers in the future.
Ashok Kumar Grover
A summary of studies on the efficacy of curcumin against osteoarthritis is presented as an example so as to provoke a dialog on the desired direction of Ayurvedic medicine research. Turmeric, the powder of dried rhizome of Curcuma longa, has been used in Ayurvedic medicine and is a household spice today. It contains over twenty potentially active compounds - one of which is curcumin . It was first extracted from turmeric about 200 years ago . In vitro and clinical studies have focused o...
Ashok Kumar Grover
Full Text Available A summary of studies on the efficacy of curcumin against osteoarthritis is presented as an example so as to provoke a dialog on the desired direction of Ayurvedic medicine research. Turmeric, the powder of dried rhizome of Curcuma longa, has been used in Ayurvedic medicine and is a household spice today. It contains over twenty potentially active compounds - one of which is curcumin . It was first extracted from turmeric about 200 years ago . In vitro and clinical studies have focused on the potential role of this compound for management of osteoarthritis and other chronic inflammatory diseases for which there is no known cure.
Gunturu Krishna S
Full Text Available Abstract Although the majority of published cases of lead poisoning come from occupational exposures, some traditional remedies may also contain toxic amounts of lead. Ayurveda is a system of traditional medicine that is native to India and is used in many parts of world as an alternative to standard treatment regimens. Here, we report the case of a 58-year-old woman who presented with abdominal pain, anemia, liver function abnormalities, and an elevated blood lead level. The patient was found to have been taking the Ayurvedic medicine Jambrulin prior to presentation. Chemical analysis of the medication showed high levels of lead. Following treatment with an oral chelating agent, the patient's symptoms resolved and laboratory abnormalities normalized. This case highlights the need for increased awareness that some Ayurvedic medicines may contain potentially harmful levels of heavy metals and people who use them are at risk of developing associated toxicities.
Somanathan, A.R.; Sadanandan, K.; Damodaran, N.P.
In a project on the analysis and standardization of Ayurvedic medicines, a chemical methodology for Dasamulam Kasayam for the comparison of market samples with a laboratory sample of Dasamulam Kasayam, and recording of characteristics like colour, consistency, smell, taste acidity, density, water soluble content and ash content. Adsorption of the Kasayam on silicagel, followed by extraction with selected solvents (petroleum ether, CHCL3, EtOAc and EtOH) as well as TLC pattern of each extract,...
Full Text Available Ayurveda is a holistic system of natural health care that originated from Vedas, most ancient Indian literature of human civilization. As it deals with various aspects of life it is not merely the system of treatment but is an “Ideal way of Life”. The main aim of Ayurveda is to maintain the health in a healthy person and to cure the disease. To attain this Ayurveda mainly concentrates on various rules and regulations. In Ayurvedic classics, food is mentioned as one among the three Upasthambas (Sub-pillars which supports the three main Sthambas (Pillars of the body viz. Tridosha. It shows the credibility of food. Food also plays role like medicine which helps to prevent or cure to diseases. Food taken in proper manner helps in the proper growth of the body on contrary if taken in improper manner leads to various diseases. Thus Diet plays a significant task in both causation and curing of the disease. Properly followed dietetic rules and diet keeps the body healthy and prevents the diseases.
Full Text Available Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant species in India, Eastern Himalayas, Western Ghats and Andman and Nicobar Islands are the hot spot for medicinal plants. Officially documented plants with medicinal potential are 3000 but traditional practitioner use more than 6000. Seventy percent of the population in the rural India is dependent on the ayurvedic system of medicine. Most of the drugs used in modern medicine and ancient Indian medicinal system are of plant origin. Beside plants many minerals, salts and animal products are used in Ayurvedic medicines. Homoeopathy originated in west, German physician Samuel Hanemann was the father of homoeopathy (1796, the homeopathic remedies are prepared by successive dilution followed by shaking forcefully. Homoeopathy uses animal, plant, mineral, and synthetic substances in its remedies. Arsenicum album (arsenic oxide, Natrum muriaticum (sodium chloride, opium (plant, and thyroidinum (thyroid hormone are some of the homoeopathic medicines extracted from different sources.
Concentrations of 15 elements were determined in medicinally important ayurvedic medicinal leaves. Instrumental neutron activation analysis was employed for the determination of the elements viz. Na, K, Br, Sm, Cr, Zn, Th, Rb, Sr, Fe, La, Co, Ce, Cs and Eu. The samples were neutron irradiated at 100 kW TRIGA -Mainz nuclear reactor and the induced activities were measured by gamma ray spectrometry using an efficiency calibrated high resolution high purity germanium (HPGe) detector. The concentrations of these elements in the medicinal leaves and their medicinal importance are discussed. (author)
Ilango Kaliappan; Ananth Kumar Kammalla; Mohan Kumar Ramasamy; Aruna Agrawal; Govind Prasad Dubey
Ayurveda is the most ancient system of traditional medicine of the world has been practicing in India. It has been facing constant challenges like standardization and pharmacokinetic profile of biomarkers in the Ayurvedic formulations. Due to these challenges there will be a potential decrease in the global herbal market. Presently Indian herbal market is about US $1.1 billion whereas Chinese herbal market is about US $10 billion per annum. Thus there is an urgent need of standardization and ...
Teerthe, Santoshkumar S.; Kerur, B. R., E-mail: email@example.com [Department of Physics, Gulbarga University, Gulbarga, and Karnataka, India – 585106 (India)
India has a rich country for the uses of Ayurvedic medicinal plants for treatment and also the north- Karnataka boasts an unparallel diversity of medicinal plants. The present study attempts to estimate and compare the level of trace and heavy metals in some selected leaves and root samples of Ayurvedic medicinal plants such as Mg, Al, K, Cr, Mn, Fe, Cu, Zn, and Cd. The samples are collected from different places of North-Karnataka regions and sample solutions prepared as the ratio of 1:25:25+950ml=1000ppm.the trace and heavy elemental concentration was estimated using Atomic Absorption Spectrometric (AAS) Method. The average concentrations of Mg, Mn, Fe and Zn, are ranging from 2ppm to 5250.2ppm and potassium (K) has more concentration as compare to all other. The other elements likes Al, Cr, Cu, and Cd were also estimed and presented in the table. Therefore, these medicinal plants are rich in some essential minerals, especially K, Mg, Mn, Fe and Zn which are essential for human health.
Teerthe, Santoshkumar S.; Kerur, B. R.
India has a rich country for the uses of Ayurvedic medicinal plants for treatment and also the north- Karnataka boasts an unparallel diversity of medicinal plants. The present study attempts to estimate and compare the level of trace and heavy metals in some selected leaves and root samples of Ayurvedic medicinal plants such as Mg, Al, K, Cr, Mn, Fe, Cu, Zn, and Cd. The samples are collected from different places of North-Karnataka regions and sample solutions prepared as the ratio of 1:25:25+950ml=1000ppm.the trace and heavy elemental concentration was estimated using Atomic Absorption Spectrometric (AAS) Method. The average concentrations of Mg, Mn, Fe and Zn, are ranging from 2ppm to 5250.2ppm and potassium (K) has more concentration as compare to all other. The other elements likes Al, Cr, Cu, and Cd were also estimed and presented in the table. Therefore, these medicinal plants are rich in some essential minerals, especially K, Mg, Mn, Fe and Zn which are essential for human health
Ragozin, Boris Vladimirovich
Ayurveda is one of the world's oldest medical sciences, with a history that goes back more than 5,000 years. The knowledge of Ayurveda has at various times had an impact on a number of branches of medicine: From ancient Greek medicine in the West to the Chinese and Tibetan in the East. Ayurveda continues to retain its prominent position in our modern world, being officially recognised by the World Health Organisation (WHO) and enjoying great popularity in the US, Germany, Italy and the Netherlands. In India, Ayurveda is recognised by conventional medicine on a par with modern medical science. In the Soviet Union a strong interest in Ayurveda arose for the first time after the Chernobyl disaster, and since then Ayurveda has been actively developing in Russia. In this article we present the chronology of the development of Ayurvedic medicine in Russia since 1989, explore academic literature on the subject available in Russian and review the existing Ayurvedic products and services offered on the Russian market. PMID:27143798
India has a rich country for the uses of Ayurvedic medicinal plants for treatment and also the north- Karnataka boasts an unparallel diversity of medicinal plants. The present study attempts to estimate and compare the level of trace and heavy metals in some selected leaves and root samples of Ayurvedic medicinal plants such as Mg, Al, K, Cr, Mn, Fe, Cu, Zn, and Cd. The samples are collected from different places of North-Karnataka regions and sample solutions prepared as the ratio of 1:25:25+950ml=1000ppm.the trace and heavy elemental concentration was estimated using Atomic Absorption Spectrometric (AAS) Method. The average concentrations of Mg, Mn, Fe and Zn, are ranging from 2ppm to 5250.2ppm and potassium (K) has more concentration as compare to all other. The other elements likes Al, Cr, Cu, and Cd were also estimed and presented in the table. Therefore, these medicinal plants are rich in some essential minerals, especially K, Mg, Mn, Fe and Zn which are essential for human health
M. M. Pandey
Full Text Available Food is the major source for serving the nutritional needs, but with growing modernization some traditional ways are being given up. Affluence of working population with changing lifestyles and reducing affordability of sick care, in terms of time and money involved, are some of the forces that are presently driving people towards thinking about their wellness. There has been increased global interest in traditional medicine. Efforts to monitor and regulate traditional herbal medicine are underway. Ayurveda, the traditional Indian medicine, remains the most ancient yet living traditions. Although India has been successful in promoting its therapies with more research and science-based approach, it still needs more extensive research and evidence base. Increased side effects, lack of curative treatment for several chronic diseases, high cost of new drugs, microbial resistance and emerging, diseases are some reasons for renewed public interest in complementary and alternative medicines. Numerous nutraceutical combinations have entered the international market through exploration of ethnopharmacological claims made by different traditional practices. This review gives an overview of the Ayurvedic system of medicine and its role in translational medicine in order to overcome malnutrition and related disorders.
Full Text Available The potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article describes a comprehensive therapeutic approach used in Ayurveda and modern medicine to treat arthritis. We present concise summary of various controlled drug trials carried out by us to validate standardized Ayurvedic drugs using modern medicine protocol to treat Rheumatoid Arthritis and Osteoarthritis knees. Several of the latter are published. The trials consistently demonstrate excellent safety of Ayurvedic medicines but often fail to unequivocally show superior efficacy. Some key findings of a recently unpublished trial in OA knees are also presented to show equivalence between Ayurvedic medicine and celecoxib and glucosamine, and we speculate that equivalence trials may be a way forward. The data from the trials also supports the Ayurvedic ′Rasayana′ concept of immune-modulation and healing. We need to interpret logic of Ayurveda when, adopting modern science tools in drug development and validation and much research is required. Validation of Ayurvedic medicines using the latter approach may lead to an evidence based Ayurveda - Modern Medicine interface. Also, in pursuit of finding better treatment solutions, we ought to step beyond the realm of only drugs and attempt validation of comprehensive specific treatment package as per classical Ayurveda. Finally, validation of a combined (Ayurveda and modern medicine therapeutic approach with superior efficacy and safety is likely to be a major leap in overcoming some of the current frustrations to treat difficult disorders like arthritis using only modern medicines.
Yoshida, Yoshitoku; Harun-Or-Rashid, Md; Yoshida, Yasuko; Alim, Md Abdul
Bangladesh is now facing the public health problems of deficiency of iron and iodine, especially for women. The Ministry of Health and Family Welfare of Bangladesh has implemented strong countermeasures to enhance the health condition of the nation. On the other hand, based on the concept of the Declaration of Alma-Ata, complementary and alternative medicine should be used more vigorously to enhance public health in the world. The usage of complementary and alternative medicine such as ayurvedic medicine (AM) should be increased in Bangladesh. Therefore we conducted the study on perceptions of AM by citizens in Dhaka, Bangladesh in order to promote and enhance the effective usage of AM, including herbal medicines as medical resources, from December 2010 to January 2011. This study showed younger citizens (61.1%) did not get more benefit from AM than elder citizens (48.0%). On the other hand, younger citizens (76.8%) did not get more harm from AM than elder citizens (70.1%). We think that in terms of effectiveness of AM, the younger generation in Dhaka seems to be more skeptical to AM than the elder generation in Dhaka, even though the younger generation are more satisfied with AM than the elder generation. With viewpoint of enhancement of usage of AM in Dhaka, we think that scientifically sound information on AM should be collected rigorously and brought to the citizens vigorously to remove the skeptical feeling of AM from younger citizen in Dhaka. In terms of the effective utilization of limited medical resources, AM should be used appropriately in Bangladesh, Asia and the world. PMID:27019531
Sethiya, Neeraj Kumar; Nahata, Alok; Mishra, Sri Hari; Dixit, Vinod Kumar
Shankhpushpi is an Ayurvedic drug used for its action on the central nervous system, especially for boosting memory and improving intellect. Quantum of information gained from Ayurvedic and other Sanskrit literature revealed the existence of four different plant species under the name of Shankhpushpi, which is used in various Ayurvedic prescriptions described in ancient texts, singly or in combination with other herbs. The sources comprise of entire herbs with following botanicals viz., Convulvulus pluricaulis Choisy. (Convulvulaceae), Evolvulus alsinoides Linn. (Convulvulaceae), Clitoria ternatea Linn. (Papilionaceae) and Canscora decussata Schult. (Gentianaceae). A review on the available scientific information in terms of pharmacognostical characteristics, chemical constituents, pharmacological activities, preclinical and clinical applications of controversial sources of Shankhpushpi is prepared with a view to review scientific work undertaken on Shankhpushpi. It may provide parameters of differentiation and permit appreciation of variability of drug action by use of different botanical sources. PMID:19912732
Bhargava Shobha Y; Zinjarde Smita S; P Sudha; Kumar Ameeta R
Abstract Background Indian medicinal plants used in the Ayurvedic traditional system to treat diabetes are a valuable source of novel anti-diabetic agents. Pancreatic α-amylase inhibitors offer an effective strategy to lower the levels of post-prandial hyperglycemia via control of starch breakdown. In this study, seventeen Indian medicinal plants with known hypoglycemic properties were subjected to sequential solvent extraction and tested for α-amylase inhibition, in order to assess and evalu...
Analysis of Chromium, Vanadium, Iron, Copper and Zinc known to influence the glucose/ insulin system was carried out in 36 different Ayurvedic medicinal plant species used to control and treat diabetes in Sri Lanka using the Energy Dispersive X ray fuorescence technique. Chromium, which is an essential nutrient in carbohydrate and lipid metabolism, was measured in 7 plant species ranging from 13-82 ppm dry ash weight. Polarographic analysis showed that one fourth of the chromium was present in the trivalent state in all seven plant species namely Ficus banghalensis, Ficus racemosa, Musa pradisiaca, Coccinea grandis, Benincasa hispida, Pongamia pinnata and Acacia nilotica. The importance of the other metals in the control of diabetes is also briefly discussed
Joshi, R. P.; Veena Joshi
Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant ...
Gewali, M B; Pilapitiya, U; Hattori, M; Namba, T
From a Kshara Sutra thread which is used in the therapy of fistula in the Ayurvedic medicinal system, euphol, 3,12-di-O-acetyl-8-O-benzoylingol, 3,12-di-O-acetyl-8-O-tigloylingol, curcumin, p-coumaroylferuloylmethane and di-p-courmaroylmethane were isolated and characterized. In addition, GLC and GC/MS confirmed the presence of euphol, antiquol B, cycloeucalenol and 24-methylene cycloartanol in the thread. PMID:2374431
Bhavana Prasher; Greg Gibson; Mitali Mukerji
Ayurveda, an ancient Indian system of medicine documented and practised since 1500 B.C., follows a systems approach that has interesting parallels with contemporary personalized genomic medicine approaches to the understanding and management of health and disease. It is based on the trisutra, which are the three aspects of causes, features and therapeutics that are interconnected through a common organizing principle termed ‘tridosha’. Tridosha comprise three ascertainable physiological entities; vata (kinetic), pitta (metabolic) and kapha (potential) that are pervasive across systems, work in conjunction with each other, respond to the external environment and maintain homeostasis. Each individual is born with a specific proportion of tridosha that are not only genetically determined but also influenced by the environment during foetal development. Jointly they determine a person’s basic constitution, which is termed their ‘prakriti’. Development and progression of different diseases with their subtypes are thought to depend on the origin and mechanism of perturbation of the doshas, and the aim of therapeutic practice is to ensure that the doshas retain their homeostatic state. Similarly, western systems biology epitomized by translational P4 medicine envisages the integration of multiscalar genetic, cellular, physiological and environmental networks to predict phenotypic outcomes of perturbations. In this perspective article, we aim to outline the shape of a unifying scaffold that may allow the two intellectual traditions to enhance one another. Specifically, we illustrate how a unique integrative ‘Ayurgenomics’ approach can be used to integrate the trisutra concept of Ayurveda with genomics. We observe biochemical and molecular correlates of prakriti and show how these differ significantly in processes that are linked to intermediate patho-phenotypes, known to take different course in diseases. We also observe a significant enrichment of the highly
Prasher, Bhavana; Gibson, Greg; Mukerji, Mitali
Ayurveda, an ancient Indian system of medicine documented and practised since 1500 B.C., follows a systems approach that has interesting parallels with contemporary personalized genomic medicine approaches to the understanding and management of health and disease. It is based on the trisutra, which are the three aspects of causes, features and therapeutics that are interconnected through a common organizing principle termed 'tridosha'. Tridosha comprise three ascertainable physiological entities; vata (kinetic), pitta (metabolic) and kapha (potential) that are pervasive across systems, work in conjunction with each other, respond to the external environment and maintain homeostasis. Each individual is born with a specific proportion of tridosha that are not only genetically determined but also influenced by the environment during foetal development. Jointly they determine a person's basic constitution, which is termed their 'prakriti'. Development and progressi on of different diseases with their subtypes are thought to depend on the origin and mechanism of perturbation of the doshas, and the aim of therapeutic practice is to ensure that the doshas retain their homeostatic state. Similarly, western systems biology epitomized by translational P4 medicine envisages the integration of multiscalar genetic, cellular, physiological and environmental networks to predict phenotypic outcomes of perturbations. In this perspective article, we aim to outline the shape of a unifying scaffold that may allow the two intellectual traditions to enhance one another. Specifically, we illustrate how a unique integrative 'Ayurgenomics' approach can be used to integrate the trisutra concept of Ayurveda with genomics. We observe biochemical and molecular correlates of prakriti and show how these differ significantly in processes that are linked to intermediate patho-phenotypes, known to take different course in diseases. We also observe a significant enr ichment of the highly connected
P K Debnath
Full Text Available Background: Pulmonary tuberculosis (PTB is an age old disease described in Vedic Medicine as ′Yakshma′. Later on, in Ayurveda it earned a prefix and found way into mythology as ′Rajayakshma′. After the discovery of streptomycin, the therapeutic management of PTB received a major breakthrough. The treatment module changed remarkably with the formulation of newer anti-tubercular drugs (ATD with appreciable success. Recent resurgence of PTB in developed countries like United States posed a threat to the medical community due to resistant strains. Consequently, WHO looked toward traditional medicine. Literature reveals that Ayurvedic treatment of PTB was in vogue in India before the introduction of ATD with limited success. Records show that 2766 patients of PTB were treated with Ayurvedic drugs in a tertiary care hospital in Kolkata in the year 1933-1947. Objectives: To evaluate the toxicity reduction and early restoration by adjunct therapy of Ayurvedic drugs by increasing the bio-availability of ATDs. Materials and Methods: In the present study, treatment response of 99 patients treated with ATD as an adjunct with Aswagandha (Withania somnifera and a multi-herbal formulation described in Chikitsa-sthana of Charaka samhita i.e. Chyawanprash were investigated. Hematological profile, sputum bacterial load count, immunoglobulin IgA and IgM, blood sugar, liver function test, serum creatinine were the assessed parameters besides blood isoniazid and pyrazinamide, repeated after 28 days of treatment. Results: The symptoms abated, body weight showed improvement, ESR values were normal, there was appreciable change in IgA and IgM patterns and significantly increased bioavailability of isoniazid and pyrazinamide were recorded. Conclusion: This innovative clinical study coupled with empowered research may turn out to be promising in finding a solution for the treatment of PTB.
Conclusions: In the present research, a rapid HPLC-MS/MS method has been developed for the identification of phytoestrogens and other flavonoids from an Ayurvedic proprietary medicine. Phytoestrogens are considered to play an important role in the prevention of cancers, heart disease, menopausal symptoms and osteoporosis.
Bhargava Shobha Y
Full Text Available Abstract Background Indian medicinal plants used in the Ayurvedic traditional system to treat diabetes are a valuable source of novel anti-diabetic agents. Pancreatic α-amylase inhibitors offer an effective strategy to lower the levels of post-prandial hyperglycemia via control of starch breakdown. In this study, seventeen Indian medicinal plants with known hypoglycemic properties were subjected to sequential solvent extraction and tested for α-amylase inhibition, in order to assess and evaluate their inhibitory potential on PPA (porcine pancreatic α-amylase. Preliminary phytochemical analysis of the lead extracts was performed in order to determine the probable constituents. Methods Analysis of the 126 extracts, obtained from 17 plants (Aloe vera (L. Burm.f., Adansonia digitata L., Allium sativum L., Casia fistula L., Catharanthus roseus (L. G. Don., Cinnamomum verum Persl., Coccinia grandis (L. Voigt., Linum usitatisumum L., Mangifera indica L., Morus alba L., Nerium oleander L., Ocimum tenuiflorum L., Piper nigrum L., Terminalia chebula Retz., Tinospora cordifolia (Willd. Miers., Trigonella foenum-graceum L., Zingiber officinale Rosc. for PPA inhibition was initially performed qualitatively by starch-iodine colour assay. The lead extracts were further quantified with respect to PPA inhibition using the chromogenic DNSA (3, 5-dinitrosalicylic acid method. Phytochemical constituents of the extracts exhibiting≥ 50% inhibition were analysed qualitatively as well as by GC-MS (Gas chromatography-Mass spectrometry. Results Of the 126 extracts obtained from 17 plants, 17 extracts exhibited PPA inhibitory potential to varying degrees (10%-60.5% while 4 extracts showed low inhibition ( 50% was obtained with 3 isopropanol extracts. All these 3 extracts exhibited concentration dependent inhibition with IC50 values, viz., seeds of Linum usitatisumum (540 μgml-1, leaves of Morus alba (1440 μgml-1 and Ocimum tenuiflorum (8.9 μgml-1. Acarbose as the
Kamat Rajeshwari V
Full Text Available The present paper is based on clinical success story in a very interesting and encouraging casein blockage of both fallopian tubes. Success was achieved with unique classical Ayurvedic formulations after 6 months treatment which will be representeding the full paper.
Nadar, T S; Pillai, M M
Biochemical and histochemical studies revealed decreased beta-glucuronidase activity in the Brunner's glands of duodenal ulcerated rats. The enzyme activity showed gradual increase during recovery. Rats treated with a mixture of Ayurvedic medicines (Glycyrrhiza glabra, Terminalia chebula, Piper longum and Shanka Bhasma) recovered faster with concomitant increase in beta-glucuronidase activity in the Brunner's glands. It can be concluded that Ayurvedic medicines used do not act as antacid but improve the secretory status of Brunner's glands involved in the protection against duodenal ulcer. PMID:2620935
Full Text Available Agasthya [Sesbania grandiflora (L Pers.] a traditionally revered Ayurvedic medicinal plant especially in Southern India. It goes as a principal ingredient in preparation of Ayurvedic medicinal formulations. Classical texts of Ayurveda have attributed wide ranging therapeutic indications to the herb. Agasthya leaves are known to possess anthehelmintic, alixeteric properties aperient, tonic, diuretic, and laxative properties. Further, they have been documented as therapeutically useful in Kaphaja disorders, pruritis, skin disorders, night blindness, epilepsy, gout, ophthalmia nasal catarrh and headache. The leaves contain a non-poisonous saponin. The present study is an attempt to decipher the rationality of the traditional use of leaves with an Ayurvedic perspective vis-à-vis pharmacognostical and physicochemical evaluation of the plant.
Sulaiman CT; Arun A; Anandan EM; Sandhya CR; Indira Balachandran
Objective: To develop analytical methods for the isolation and structural identification of poly phenols including phytoestrogens in Mensokot tablet, a herbal proprietary medicine. Methods:Isolation consisted of an ultrasound-assisted extraction, followed by acid hydrolysis and a final liquid-liquid extraction step in diethyl ether. Identification and structural characterisation was done by liquid chromatography coupled with Q-TOF-ESI-MS/MS analysis. Results:Phytoestrogens such as Coumestrol, Genistein and Glycitein have been identified in Mensokot tablet along with several other flavonoids. Conclusion: In the present research, a rapid HPLC-MS/MS method has been developed for the identification of phytoestrogens and other flavonoids from an Ayurvedic proprietary medicine. Phytoestrogens are considered to play an important role in the prevention of cancers, heart disease, menopausal symptoms and osteoporosis.
Kilankaje, Ashakiran; ,
Purpose: Introduction of Plant tissue culture (PTC) concept to the Ayurveda realm. Method: 1. Analysis of principles the plant tissue culture based on the literature review and real wet lab images of tissue culture 2. Analysis of ayurvedic principles which are relevant in the context 3. Logical concept development. Result: Plant tissue culture is based on the natural ability of plant cells to grow in to fullfledged organism, called as totipotency. Plant cell can exhibit totipotency only when ...
Meenakshi, C.; Jayabal, P.; Ramakrishnan, V.
The thermodynamic property of the host-guest complexes formed between the curcumin, component of Indian Ayurvedic medicine turmeric, a drug molecule, with the supra molecule, p-t-butyl calix(8)arene was studied. p-t-Butyl calix(8)arene has been used as a host molecule and curcumin as a guest molecule. Optical absorption spectral studies were carried out to investigate the molecular recognition properties of p-t-butyl calix(8)arene with curcumin. The stochiometry of the host-guest complexes formed and the binding constant were determined. An interesting 1:1 and 4:1 stochiometric host-guest complexes were formed. Job's continuous method of variation and Benesi-Hildebrand expression were used for the determination of binding constant and the stochiometry of the host-guest complex formed.
Full Text Available Background: Hyperlipidemia is a major risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Arogyavardhini vati, an Ayurvedic polyherbal formulation has been used for liver disorders. Therefore, present study was designed to evaluate the effect of Arogyavardhini vati in Triton WR-1339-induced hyperlipidemia in rats. Objectives: Anti-hyperlipidemic activity evaluation of Arogyavardhini vati against Triton WR-1339-induced hyperlipidemia in rats. Materials and Methods: Overnight fasted male Wistar rats (150-200 g were randomly divided into normal control group [4% Dimethyl Sulfoxide (DMSO, i.p.], positive control group (Triton WR-1339 in 4% DMSO, 400 mg/kg, i.p., standard drug treated (fenofibrate 65 mg/kg, p.o. for 7 days after inducing hyperlipidemia and Arogyavardhini vati treated (50, 100, 200 mg/kg, p.o. for 7 days after inducing hyperlipidemia. Rat doses were calculated by extrapolating the equivalent human dose (therapeutic dose, sub-maximum, and maximum dose. Serum total cholesterol, triglyceride, low-density lipoprotein (LDL, high-density lipoprotein HDL, liver malondialdehyde (MDA, and glutathione (GSH levels were estimated at end of experiments. Results: Arogyavardhini vati significantly decreased serum cholesterol, triglyceride, LDL, and C-reactive protein (CRP and significantly increased serum HDL in a dose-dependent manner. Decreased MDA and increased GSH levels in liver were observed at all doses of Arogyavardhini vati (50, 100, 200 mg/kg and fenofibrate-treated groups when compared with Triton-treated group. Atherogenic Index (AI level was significantly decreased in fenofibrate and Arogyavardhini vati (200 mg/kg treated rats when compared with normal control. Conclusion: Arogyavardhini vati, a traditionally used Ayurvedic medicine may be a useful therapy for hypercholesterolemia through reducing oxidative stress (decreasing MDA and increasing GSH and lipid
Ven Murthy, M R; Ranjekar, Prabhakar K; Ramassamy, Charles; Deshpande, Manasi
Ayurveda is a Sanskrit word, which means "the scripture for longevity". It represents an ancient system of traditional medicine prevalent in India and in several other south Asian countries. It is based on a holistic view of treatment which is believed to cure human diseases through establishment of equilibrium in the different elements of human life, the body, the mind, the intellect and the soul . Ayurveda dates back to the period of the Indus Valley civilization (about 3000 B.C) and has been passed on through generations of oral tradition, like the other four sacred texts (Rigveda, Yajurveda, Samaveda and Atharvanaveda) which were composed between 12(th) and 7(th) century B.C [2, 3]. References to the herbal medicines of Ayurveda are found in all of the other four Vedas, suggesting that Ayurveda predates the other Vedas by at least several centuries. It was already in full practice at the time of Buddha (6(th) century B.C) and had produced two of the greatest physicians of ancient India, Charaka and Shushrutha who composed the basic texts of their trade, the Samhitas. By this time, ayurveda had already developed eight different subspecialties of medical treatment, named Ashtanga, which included surgery, internal medicine, ENT, pediatrics, toxicology, health and longevity, and spiritual healing . Ayurvedic medicine was mainly composed of herbal preparations which were occasionally combined with different levels of other compounds, as supplements . In the Ayurvedic system, the herbs used for medicinal purposes are classed as brain tonics or rejuvenators. Among the plants most often used in Ayurveda are, in the descending order of importance: (a) Ashwagandha, (b) Brahmi, (c) Jatamansi, (d) Jyotishmati, (e) Mandukparni, (f) Shankhapushpi, and (g) Vacha. The general appearance of these seven plants is shown in Fig.1. Their corresponding Latin names, as employed in current scientific literature, the botanical families that each of them belongs to, their
Full Text Available Ankylosing spondylitis previously known as Bechterew's disease and Marie-Strümpell disease. It is a chronic inflammatory disease of the axial skeleton with variable involvement of peripheral joints and nonarticular structures. AS is a form of spondyloarthritis, a chronic, inflammatory arthritis where immune mechanisms are thought to play a key role. It mainly affects joints in the spine and the sacroiliac joint in the pelvis and can cause eventual fusion of the spine. The treatment of ankylosing spondylitis typically involves the use of medications to reduce inflammation, suppress immunity to stop progression of the disease, physical therapy, and exercise. Medications decrease inflammation in the spine and other joints. Physical therapy and exercise help to improve posture, spine mobility, and lung capacity. Ayurveda offers excellent therapies for treating Ankylosing spondylitis. The treatment comprises of a series of purification procedures for Detoxification through world renowned Ayurveda Panchakarma therapies along with the administration of researched medicines internally In these article treatment strategies for western system of medicine and Indian system of medicine was explained in detail. The main mechanisms involved in treating the conditions such as fever, back pain, swelling at various joints, stiffness in neck and back bone was explained. Different medicines used for the treatment of symptoms and their mechanism of action was explained properly. Strict diet restrictions along with life style modification are essential parts of the therapy. Following the diet as advised not only helps in recovering fast but also in prevents further worsening of the condition. The importance of diet in treating the condition was also explained.
Manjeshwar Shrinath Baliga; Suresh Rao; Manoj P Rai; Prema D'souza
The use of compounds which can selectively protect normal tissues against radiation injury is of immense use because in addition to it protecting the normal tissue, will also permits use of higher doses of radiation to obtain better cancer control and possible cure. However, most of the radio protective compounds investigated possess inadequate clinical application principally due to their inherent systemic toxicity at their optimal protective concentrations. Plants commonly used as medicinal...
Baliga, Manjeshwar Shrinath; Rao, Suresh; Rai, Manoj P; D'souza, Prema
The use of compounds which can selectively protect normal tissues against radiation injury is of immense use because in addition to it protecting the normal tissue, will also permits use of higher doses of radiation to obtain better cancer control and possible cure. However, most of the radio protective compounds investigated possess inadequate clinical application principally due to their inherent systemic toxicity at their optimal protective concentrations. Plants commonly used as medicinal and dietary agents have recently been the focus of attention and studies have shown that Ocimum sanctum Linn. commonly known as the Holy Basil and its water soluble flavonoids, orientin and vicenin protects experimental animals against the radiation-induced sickness and mortality at nontoxic concentrations. Studies with tumor bearing mice have also shown that both Tulsi extract and its flavonoids selectively protect the normal tissues against the tumoricidal effects of radiation. Preclinical studies have also shown that the aqueous extract of the Tulsi leaves; its flavanoids orientin and vicenin, and eugenol, the principal nonpolar constituent present in Tulsi prevent radiation-induced clastogenesis. Mechanistic studies have indicated that free radical scavenging, antioxidant, metal chelating and anti-inflammatory effects may contribute toward the observed protection. In addition, clinical studies with a small number of patients have shown that Tulsi was effective as a radio protective agent. This review summarizes the results related to the radio protective properties of Tulsi and its phytochemicals and also emphasizes the aspects that warrant future research to establish its use as a radio protective agent. PMID:27072205
Manjeshwar Shrinath Baliga
Full Text Available The use of compounds which can selectively protect normal tissues against radiation injury is of immense use because in addition to it protecting the normal tissue, will also permits use of higher doses of radiation to obtain better cancer control and possible cure. However, most of the radio protective compounds investigated possess inadequate clinical application principally due to their inherent systemic toxicity at their optimal protective concentrations. Plants commonly used as medicinal and dietary agents have recently been the focus of attention and studies have shown that Ocimum sanctum Linn. commonly known as the Holy Basil and its water soluble flavonoids, orientin and vicenin protects experimental animals against the radiation-induced sickness and mortality at nontoxic concentrations. Studies with tumor bearing mice have also shown that both Tulsi extract and its flavonoids selectively protect the normal tissues against the tumoricidal effects of radiation. Preclinical studies have also shown that the aqueous extract of the Tulsi leaves; its flavanoids orientin and vicenin, and eugenol, the principal nonpolar constituent present in Tulsi prevent radiation-induced clastogenesis. Mechanistic studies have indicated that free radical scavenging, antioxidant, metal chelating and anti-inflammatory effects may contribute toward the observed protection. In addition, clinical studies with a small number of patients have shown that Tulsi was effective as a radio protective agent. This review summarizes the results related to the radio protective properties of Tulsi and its phytochemicals and also emphasizes the aspects that warrant future research to establish its use as a radio protective agent.
Full Text Available Achalasia is an esophageal motor disorder characterized by sustained lower esophageal sphincter contraction and reduced esophageal peristalsis. This pathology eventually results in symptoms like dysphagia, regurgitation and occasional chest pain related to food intake. This is an uncommon disorder of unexplained etiology; however viral, autoimmune and neurodegenerative causes are often afflicted to its manifestation. As per the current state of knowledge, achalasia is considered to be a chronic incurable condition. The treatment options offered here primarily aim at reducing the tone of lower esophageal sphincter by pharmacologic, endoscopic or surgical means. We are presenting here a case of achalasia with two years of symptomatic history of food regurgitation, dysphagia and heart burn without any noticeable response from allopathic medicines. The patient was subsequently kept under ayurvedic therapy considering the symptoms caused by vata impairment and hence requiring vatanulomana and reduction in esophageal muscle tone as the primary management. The patient was kept under suggested Ayurvedic therapy and followed-up for 3 months. A symptom-free follow-up in this case was noticed after completion of 1 month of Ayurvedic therapy.
... prove that the approaches are beneficial. Keep in Mind Tell all your health care providers about any ... require a viewer such as the free Adobe Reader . NCCIH Pub No.: D287 Date Created: October 2005 ...
Gajendra Kumar,; Amita Srivastava; Surinder Kumar Sharma; Yogendra Kumar Gupta
Background: Hyperlipidemia is a major risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Arogyavardhini vati, an Ayurvedic polyherbal formulation has been used for liver disorders. Therefore, present study was designed to evaluate the effect of Arogyavardhini vati in Triton WR-1339-induced hyperlipidemia in rats. Objectives: Anti-hyperlipidemic activity evaluation of Arogyavardhini vati against Triton WR-1339-induce...
Full Text Available PPARs play a pivotal role in regulating lipid and glucose homeostasis and are involved in diverse biological activities in skin. Pomegranate flower (PGF, an antidiabetic therapy in Unani and Ayurvedic medicines has been previously demonstrated to activate both PPARalpha/gamma. Here, we found that treatment of mice with the diet containing PGF powder over 55 weeks attenuated ageing-induced abnormal increases in the homeostasis model assessment of insulin resistance, glucose concentrations during oral glucose tolerance test, and adipose insulin resistance index. The diet tended to decrease the excessive peri-ovary fat mass. It, however, increased the thinned subcutaneous fat thickness. In addition, the diet restored decreases in skin water content, epidermis thickness, and collagen density in corium. Thus, our results demonstrate that long-term treatment with the Unani and Ayurvedic therapy ameliorates ageing-induced insulin resistance, which is associated with reversal of ageing-induced fat redistribution. Further, PGF attenuates ageing-mediated undesirable skin abnormalities.
Mahesh.T.S; Sudheer M; Shreevidya M; Ravi Rao S; Subrahmanya P
In India, there are more than 700 Ayurvedic hospitals with more than 35,000 beds and 435,000 Ayurvedic physicians. This makes treatments and product prescriptions more readily accessible and widespread acceptance of Ayurveda. The retail value of the Ayurvedic products market in India is estimated to be around $1.2 billion (2005 figures) and is expected to reach $2.6 billion by 2012.The products of Ayurvedic medicine were not produced commercially earlier. The physician himself used to find t...
Full Text Available Ayurveda, the science of life, deals with the holistic view of healthy living. It covers various physiology as well as pathology of diseases and also their treatments. Since, Ancient times, several diseases have been treated by administration of plant extracts based on traditional medicine. Investigation of traditionally used medicinal plants thus valuable on two parts-one of them is source of potential chemotherapeutic drugs and second one is as a measure of safety for the continued use of medicinal plants. The whole plant of Astercantha longifolia is used in traditional Ayurvedic medicine for the treatment of sexual disorders, inflammatory disorders and urinary disorders.Astercantha longifolia mainly contains lupeol, stigmasterol, an isoflavone glycoside, an alkaloid and small quantities of uncharacterized bases. This paper explains the evidence based information regarding the pharmacological activity of this plant. It has many ethno botanical as well as ethno medicinal properties.
CT Sulaiman; Arun, A; EM Anandan; CR Sandhya; Indira Balachandran
Objective: To develop analytical methods for the isolation and structural identification of poly phenols including phytoestrogens in Mensokot tablet, a herbal proprietary medicine. Methods: Isolation consisted of an ultrasound-assisted extraction, followed by acid hydrolysis and a final liquid-liquid extraction step in diethyl ether. Identification and structural characterisation was done by liquid chromatography coupled with Q-TOF-ESI-MS/MS analysis. Results: Phytoestrogens such as Cou...
Santosh Kumar Maurya; Ankit Seth; Damiki Laloo; Narendra Kumar Singh; Dev Nath Singh Gautam; Anil Kumar Singh
Ayurveda involves the use of drugs obtained from plants, animals, and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. There are various crude drugs, which generally possess unwanted impurities and toxic substances, which can lead to harmful health problems. Many authors have reported that not all medicinal plants are safe to use since they can bear many toxic and harmful phytoconstituents in them. Śodhana (detoxification/purification) i...
Santosh Kumar Maurya
Full Text Available Ayurveda involves the use of drugs obtained from plants, animals, and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. There are various crude drugs, which generally possess unwanted impurities and toxic substances, which can lead to harmful health problems. Many authors have reported that not all medicinal plants are safe to use since they can bear many toxic and harmful phytoconstituents in them. Śodhana (detoxification/purification is the process, which involves the conversion of any poisonous drug into beneficial, nonpoisonous/nontoxic ones. Vatsanābha (Aconitum species, Semecarpus anacardium, Strychnos nux-vomica, Acorus calamus, Abrus precatorius etc., are some of the interesting examples of toxic plants, which are still used in the Indian system of medicine. Aconite, bhilawanols, strychnine, β-asarone, abrin are some of the toxic components present in these plants and are relatively toxic in nature. Śodhana process involves the purification as well as reduction in the levels of toxic principles which sometimes results in an enhanced therapeutic efficacy. The present review is designed to extensively discuss and understand the scientific basis of the alternative use of toxic plants as a medicine after their purification process.
Maurya, Santosh Kumar; Seth, Ankit; Laloo, Damiki; Singh, Narendra Kumar; Gautam, Dev Nath Singh; Singh, Anil Kumar
Ayurveda involves the use of drugs obtained from plants, animals, and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. There are various crude drugs, which generally possess unwanted impurities and toxic substances, which can lead to harmful health problems. Many authors have reported that not all medicinal plants are safe to use since they can bear many toxic and harmful phytoconstituents in them. Śodhana (detoxification/purification) is the process, which involves the conversion of any poisonous drug into beneficial, nonpoisonous/nontoxic ones. Vatsanābha (Aconitum species), Semecarpus anacardium, Strychnos nux-vomica, Acorus calamus, Abrus precatorius etc., are some of the interesting examples of toxic plants, which are still used in the Indian system of medicine. Aconite, bhilawanols, strychnine, β-asarone, abrin are some of the toxic components present in these plants and are relatively toxic in nature. Śodhana process involves the purification as well as reduction in the levels of toxic principles which sometimes results in an enhanced therapeutic efficacy. The present review is designed to extensively discuss and understand the scientific basis of the alternative use of toxic plants as a medicine after their purification process. PMID:26283803
Mahesh T S
Full Text Available In India, there are more than 700 Ayurvedic hospitals with more than 35,000 beds and 435,000 Ayurvedic physicians. This makes treatments and product prescriptions more readily accessible and widespread acceptance of Ayurveda. The retail value of the Ayurvedic products market in India is estimated to be around $1.2 billion (2005 figures and is expected to reach $2.6 billion by 2012.The products of Ayurvedic medicine were not produced commercially earlier. The physician himself used to find the raw material and prepare the medicine by himself or under his supervision. But, due to change in lifestyles, and scarcity of raw materials, the physician was unable to fulfill the rising demand. Thus, commercial production of Ayurvedic medicines started in recent decades. As the Ayurvedic drug industry deals mainly with those of herbal, mineral, animal or their combination drugs, the quality of the raw material and in turn the quality of the products play a very important role in marketing when compared to the other three elements of marketing mix. Thus, to determine the influence of marketing, its concepts on the sale of Ayurvedic drugs the study is undertaken.
Full Text Available Doctrines of Ayurveda have momentous value even in the life of present day human life. These principles are based on the extraordinary observations and experimentations at various levels. Hence one cannot easily deny the observations put forward by the philosophers. According to one of its great preceptors Charaka- the dictum of Ayurveda is to maintain health of healthy people and to alleviate disorders in the diseased persons. The references of medicinal uses of herbs are recorded in Rgveda and Atharvaveda. Nighantus, the well-known compilations- are the very rich sources of herbal drug data ranging from identification, collection to therapeutics uses of the drugs.Since previous two decades there has been an increasing status emphasized on screening of herbs for hypolipidemic actions in order to reduce the risk of heart and other related disease. The high expenses and side effects of hyperlipidemia medications have led many populaces to search for alternate treatments. Only a few studies have been conducted to evaluate the effect of herbs mentioned in Ayurvedic texts on hyperlipidemia. Capparis Deciduas F., Ricinus Communis L., and Zizyphus Jujuba L. are traditionally used as antihyperlipidemic drugs as per Ayurvedic literature. Hence the present study was undertaken to investigate the antihyperlipidemic effect of a polyherbal formulation, prepared using the above three medicinal plants against Triton WR-1339 and High fat diet induced hyperlipidemia in rats. The probable mechanism of action of the extract may be inhibition of HMG-CoA reductase enzyme pathway.
Systematic studies on the accumulation of 210Po in twelve medicinal plants and activity concentration in associated soils have been carried out. The activity of 210Po was measured using ZnS (Ag) alpha counting system. The mean 210Po activity concentration was found to be 27.8 Bq kg-1 and 8.3 Bq kg-1 for plant and soil respectively. The plant to soil mean activity ratio of 210Po was found to be 3.8. A good correlation was observed between the activity concentration of 210Po in plant and soil. The absorbed gamma dose rates in the study are measured using portable scintillometer varies in the range 34.8 nGy h-1 - 52.2 nGy h-1 with a mean value of 43.5 nGy h-1. The results of these systematic investigations are presented and discussed. (author)
Patwardhan, Kishor; Gehlot, Sangeeta; Singh, Girish; Rathore, H C S
In the present day scenario, Ayurveda is globally being perceived in several contradictory ways. Poor quality of Ayurveda graduates produced as a result of poorly structured and poorly regulated education system is at least one of the important factors responsible for this scenario. The present study was carried out to evaluate the 'Global challenges of graduate level Ayurvedic education' and is based on the responses of Ayurvedic students and Ayurvedic teachers from various educational institutions of India to a methodically validated questionnaire. As the study indicates, the poor standard of Ayurvedic education in India is definitely a cause of concern. The curriculum of Bachelor of Ayurvedic Medicine and Surgery (BAMS) course of studies is required to be reviewed and restructured. The syllabi are required to be updated with certain relevant topics like laws governing the intellectual property rights, basic procedures of standardization of medicinal products, fundamental methods of evaluating the toxicity of the medicinal products, essentials of healthcare management and the basics of cultivation and marketing of medicinal plants. Furthermore, the study suggests that the Ayurvedic academicians are required to be trained in standard methods of research and documentation skills, and the educational institutions are required to be encouraged to contribute their share in building up the evidence base for Ayurveda in the form of quality education and research. PMID:20532099
Neeraj Kumar SETHIYA; Alok NAHATA; Sri Hari MISHRA; Vinod Kumar DIXIT
Shankhpushpi is an Ayurvedic drug used for its action on the central nervous system, especially for boosting memory and improving intellect. Quantum of information gained from Ayurvedic and other Sanskrit literature revealed the existence of four different plant species under the name of Shankhpushpi, which is used in various Ayurvedic prescriptions described in ancient texts, singly or in combination with other herbs. The sources comprise of entire herbs with following botanicals viz., Convulvulus pluricaulis Choisy. (Convulvulaceae), Evolvulus alsinoides Linn. (Convulvulaceae), Clitoria ternatea Linn. (Papilionaceae) and Canscora decussata Schult. (Gentianaceae). A review on the available scientific information in terms of pharmacognostical characteristics, chemical constituents, pharmacological activities, preclinical and clinical applications of controversial sources of Shankhpushpi is prepared with a view to review scientific work undertaken on Shankhpushpi. It may provide parameters of differentiation and permit appreciation of variability of drug action by use of different botanical sources.%土丁桂属草药是作用于中枢神经系统的印度传统药物,特别是对促进记忆和改善智力有较好疗效.从印度传统医学和梵语文献中提取的大量信息提示,冠以土丁桂属草药名称的植物类别共4种:旋花科田旋花、旋花科土丁桂、蝶形花科蝴蝶花豆和龙胆科穿心草.这些草药名称均在古代文献中有所记载,可单独使用或与其他药材组合成各种草药处方.本文就现有的科学信息,如土丁桂属不同植物来源物种的生药学特征、化学成分、药理作用、临床前及临床应用等方面进行述评,以期为科学地应用土丁桂提供依据.此外,还可根据不同植物来源土丁桂属草药的不同功效进行鉴别应用.
The growing interest in using Ayurvedic medicine as a gentler, safer option to using modern medicine drugs with attendant side effects continues to be thwarted because claims about effectiveness and safety are not backed with evidence and clinical data. The focus of Ayurveda practice and research should be on building bridges to this knowledge for public benefit. The consumer is being denied basic knowledge, access to product information as well the benefit of a common prescription written by a single treating physician because of three factors - Ayurvedic OTC medicine is generally sold with names and labels which cannot be understood by the consumer despite being easily available without prescription; the treating modern medicine doctor is being prevented from writing the name of a herbal product even when he is individually convinced about its usefulness (in given circumstances) and the absence of biomedical research using objective parameters proving the effectiveness of the drugs. Contemporary Ayurveda needs to be packaged to reach the modern consumer in a way that he gets the benefit of access to treatment options that assist healing within the ambit of the law. These obstacles have to be removed. Patient- based effectiveness studies using retrospective case material as well as research using interdisciplinary approaches are needed for public benefit. This has to be facilitated. PMID:27297503
Vinit D. Patel; Namrata A. Desai; Praboth V Shah; Patel, Snehal S
Background: Rheumacure (RC) is a herbomineral preparation recommended by Ayurvedic medical practitioners for treatment of rheumatoid arthritis. The present study was designed to evaluate the effect of oral treatment with the herbomineral formulation in animal model of Freunds adjuvant induced arthritis to develop scientific evidence to the efficacious claim of the use of ayurvedic proprietary medicine in the management of rheumatoid arthritis in folklore medicine. Methods: Arthritis was in...
Singh, Sarvesh Kumar; Rajoria, Kshipra
Ankylosing spondylitis (AS) is a rheumatic disease with various skeletal and extra skeletal manifestations. No satisfactory treatment is available in modern medicine for this disorder. Various Panchakarma procedures and Ayurvedic drugs have been proved useful for these manifestations. We present a case of AS, which was treated for two months with a combination of Panchakarma procedures and Ayurvedic drugs. Ayurvedic treatments, in this case, were directed toward alleviating symptoms and to reduce severe disability. The patient was considered suffering from Asthimajja gata vata (∼Vata disorder involving bone and bone marrow) and was treated with Shalishastika Pinda Svedana (sudation with medicated cooked bolus of rice) for one month and Mustadi Yapana Basti (enema with medicated milk) with Anuvasana (enema with Asvagandha oil) in 30 days schedule along with oral Ayurvedic drugs for two months. Pratimarsha nasya (nasal drops) with Anu Taila (oil) for one month was given after completion of Basti procedure. Patient's condition was assessed for symptoms of Asthimajja gata vata and core sets of Assessment of Spondylo Arthritis International Society showed substantial improvement. This study shows the cases of AS may be successfully managed with Ayurvedic treatment. PMID:27297511
Full Text Available Quality Ayurvedic herbal medicines are potential, low-cost solutions for addressing contemporary healthcare needs of both Indian and global community. Correlating Ayurvedic herbal preparations with modern processing principles (MPPs can help develop new and use appropriate technology for scaling up production of the medicines, which is necessary to meet the growing demand. Understanding the fundamental Ayurvedic principles behind formulation and processing is also important for improving the dosage forms. Even though Ayurvedic industry has adopted technologies from food, chemical and pharmaceutical industries, there is no systematic study to correlate the traditional and modern processing methods. This study is an attempt to provide a possible correlation between the Ayurvedic processing methods and MPPs. A systematic literature review was performed to identify the Ayurvedic processing methods by collecting information from English editions of classical Ayurveda texts on medicine preparation methods. Correlation between traditional and MPPs was done based on the techniques used in Ayurvedic drug processing. It was observed that in Ayurvedic medicine preparations there were two major types of processes, namely extraction, and separation. Extraction uses membrane rupturing and solute diffusion principles, while separation uses volatility, adsorption, and size-exclusion principles. The study provides systematic documentation of methods used in Ayurveda for herbal drug preparation along with its interpretation in terms of MPPs. This is the first step which can enable improving or replacing traditional techniques. New technologies or use of existing technologies can be used to improve the dosage forms and scaling up while maintaining the Ayurvedic principles similar to traditional techniques.
Ashish K Sharma
Full Text Available Herbal drugs have been used since ancient times as medicines for the treatment of various diseases. Especially in countries like India many of herbal drugs and formulations are used in different practices of treatment like Ayurveda, Siddha and Unani. It is estimated that about 25% of all modern medicines are directly or indirectly derived from plants sources. The contribution of developing countries in global herbal business is very poor due to lack of quality control and standardization measures. There is lack of common standards and appropriate methods for evaluating Traditional Medicine to ensure the safety, efficacy and quality control. This indicates the importance and necessity to develop a standard operational procedure for the standardization of herbal drugs and formulations. Benchmarking the evaluation protocols including both quality control and quality assurance of herbal drugs would play a major role in providing highly reliable and effective herbals drugs and to attract international trade, thus generating revenue. The article highlights various problems being faced by developing countries and suggests a unique approach for the preparation of SOP/guidelines for the standardization of all herbal based formulations, also there is a need for systematic clinical trials of traditional plant based medicines to enhance global acceptance
Rajalakshmy M R; Sindhu A.; Geetha G
Water extraction is a major process in Ayurvedic medicine manufacturing industry. This process involves water extraction of huge quantity of herbs, which culminates in the generation of large amount of marc or herbal residue. Usually the residue is either incinerated or converted to herbal manure. This paper investigates the marc of Withania somnifera roots obtained from Ayurvedic Industry for presence of valuable and potent bioactive phytochemicals. The chances of the phytochemicals getting ...
Athikajan; Shreevathsa; Rajendra V
Any branch of science demands precision for its development, and so does the medical science. For precision facts, observations or measurements have to be expressed in a figure, which is termed as statistics. Everything in medicine be it a research, diagnosis or treatment, depends on numbers or measurement. Ayurvedic scholars had given due regard to the importance of statistical methods. The mentioning of term ‘sankhya’ and ‘maana’ in the literature of Ayurveda itself indicates the importance...
Kuntal Ghosh; Baghel, M. S.
Benincasa hispida (Thunb.) of Cucurbitaceae family commonly known as Kushmanda, Winter melon, Wax gourd, is used in Ayurvedic system of medicine. It is cultivated throughout the plains of India and on the hills up to 1200 meter altitude, as a vegetable. The Fruits of Kushmanda are considered as Diuretic (mutral), Aphrodisiac (vrishya), Appetizer (dipana); used in Acid reflux syndrome(Amlapitta), Purpura (Raktapitta), Emaciation (Kshaya), Mental disorder (Chetovikara), etc. In the present stud...
Full Text Available P.aeruginosa one of the prominent bacteria associated with wound infections and the recent years have seen an increase in the prevalence of P.aeruginosa in wound cases. Multiple drug resistant P. aeruginosa (MDRPA is defined as an isolate resistant or intermediate to at least three antipseudomonal drugs like cephalosporins, carbapenems, aminoglycosides, and fluoroquinolones. Medical community is in search of effective and novel drug against this pathogen. Recent years have witnessed the antimicrobial potential of plant sources. Hence prevalence of MDRPA among wound infections and exploration of plant extracts as antipseudomonal agents is a field confronting current research. P. aeruginosa isolates were obtained from wound infections and their resistance to eleven antibiotics were checked .69.6 % of isolates were found to be MDRPA. Imipenem was found to be the most effective antibiotic, followed by amikacin and gatifloxacin. Cold ethanolic and hot water extracts of nine medicinal plants were evaluated. The antibacterial efficacy of the extracts was checked by well diffusion. Microbroth tube dilution method was carried out to determine the minimum inhibitory concentration (MIC. The ethanolic and water extracts of the peel of P. granatum were found to be effective against MDRPA with MIC of 200 µg/ml. The development of resistance against the present drug of choice imipenem, is of particular concern. Hence the extracts of P. granatum can be used for drug innovations as antipseudomonal agents.
Santhosh B; Jadar P. G.; Nageswara Rao
Kanji – A unique Ayurvedic fermentative preparation was prepared as per the textual reference Rasayanasara which is mainly indicated for the Shodhana (purification) of Metals and also for various mercurial processing. But Kanji by this reference is rarely prepared and used. Hence, the pharmaceutical and preliminary physico-chemical findings of this Kanji are reported in this paper. The fermentation process started on 7th day and completed on 31st day. The prepared Kanji was golden brown color...
Full Text Available The recent global resurgence of interest in traditional systems of medicines has led to an increase in the demand for them. These medicines are effective but commercialization of the manufacture of these medicines to meet this increasing demand has resulted in a decline in their quality, primarily due to lack of adequate regulations pertaining to this sector of medicine. The need of the hour is to evolve a systematic approach and to develop well-designed methodologies for the standardization of herbal formulations. In the paper, attempt has been made to evaluate Sulaharana Yoga, a Ayurvedic formulation. One sample was procured from manufactures and subjected to macroscopic, microscopic characterization, physico-chemical screening, thin layer chromatography (TLC studies and was compared using in-house preparation formulation. It was observed that the commercial samples matched exactly with that of in-house preparation after performing the standardization.
Full Text Available In Ayurveda, Mental disorders and psychological temperaments have been broadly described [e.g. vata vyadhi (nervous disorders, unmada (insanity, murccha, moha (loss of consciousness, vismriti (amnesia, apasmara (epilepsy etc.]. In Ayurveda, Apasmara (or epilepsy has been described among the maharoga (a group of eight diseases well-known for causing serious morbidity. In the Ayurvedic texts, Apasmara (Epilepsy is defined as sudden abhorrent bodily activities (vibhatsa-cheshta accompanied by momentary blackouts or loss of consciousness (tama-pravesha owing to disturbance in mental faculties of dhi (intelligence, dhriti (retention and smriti (memory. Epilepsy is a major public health problem all over world. The estimated proportion of the general population with active epilepsy (i.e. continuing seizures or the need for treatment at a given time ranges from 4-10 per 1,000 people. Herbal remedies have been recommended in various medical treatises for the cure of different diseases. In this regard, there is great prospective for identifying excellent Ayurvedic components or its active principles, particularly in consideration of the fact that such substances may provide maximum advantage with cost effectiveness, least side effects, and improvement of patient compliance.
Full Text Available A female patient aged 28 years hailing from Chennai working in the department of human resource (HR, a known case of hypothyroidism & polycystic ovarian syndrome (PCOS complained of nearly about 25 kg weight gain from April 2012. She was treated for infertility with hormonal therapies. On examination she had a BMI of 42.09 kg/ m2 and diagnosed as Atisthoulya (~obesity grade III. It was managed successfully based on the Ayurvedic principle of “Guru Cha Atarpanam” which means the foods and medicines should be non-nourishing and give a sense of satiety.
Kajjali - which is a defined combination of purified elemental mercury and sulphur is used in Ayurvedic prescriptions. Kajjali is claimed to accelerate the therapeutic effects of various medicinal components. The exact role of Kajjali in this process is not as yet ascertained. Ayurveda literature claims that toxic effects of mercury are neutralised in the presence of sulphur. Mercury is known for its toxicity especially with respect to the nervous system and the amount of mercury used in the preparation of Kajjali is quite high. Hence, to study the pharmaco-kinetics of the preparation, bio-distribution studies using 203Hg as a tracer in Kajjali were carried out in Wistar rats. (author)
Full Text Available Benincasa hispida (Thunb. of Cucurbitaceae family commonly known as Kushmanda, Winter melon, Wax gourd, is used in Ayurvedic system of medicine. It is cultivated throughout the plains of India and on the hills up to 1200 meter altitude, as a vegetable. The Fruits of Kushmanda are considered as Diuretic (mutral, Aphrodisiac (vrishya, Appetizer (dipana; used in Acid reflux syndrome(Amlapitta, Purpura (Raktapitta, Emaciation (Kshaya, Mental disorder (Chetovikara, etc. In the present study fruit of Benincasa hispida was authenticated Pharmacognostically in the department of Pharmacognosy, I.P.G.T. & R.A., Gujarat Ayurveda University of Pharmacy, Jamnagar, Gujarat, India. Each and every drug has its own physical and chemical characteristics that help for separating it from other closely related drugs. Hence physicochemical studies of a particular drug by making use of various parameters help in standardizing the drug and validate it. Chromatographic techniques were adopted for the separation of active principles present in the fruit powder. Therefore, an attempt has been made to standardize Kushmanda powder, an Ayurvedic medicine based on the TLC and HPTLC fingerprint profile.
Herbal and Ayurvedic preparations, widely used in Pakistan and the developing world, present serious risk of heavy metal toxicity related to their medicinal content and prolonged use by patients. The objective of this study was to find out the concentration of heavy metals in Herbal and Ayurvedic liquid preparations commonly used for treatment of different diseases, from local markets of Hazara. Methods: The cross sectional survey of traditional herbal and Ayurvedic medicine shops included ten liquid preparations selected from local shops of Mansehra and Abbottabad after interviewing the shopkeepers; so as to select the most commonly sold preparations along with their indications. All samples were analysed on standard Atomic Absorption Spectroscopy for qualitative and quantitative study of toxic heavy metals (Mercury, Iron, Zinc, Lead, Manganese and Arsenic). Results: Toxic levels of Mercury were present in seven syrups, i.e., (Kashneeze, Akseer e Pachas, Tankar, Sharbat e folad, Urosinal, Akseer e Jigar and Amrat dhara) while Arsenic was present only in Urosinal. Iron, Zinc, Manganese and Lead were present in permissible limits in all syrups. Conclusion: Mercury and Arsenic are present in local Herbal and Ayurvedic liquid preparations far beyond the permissible limits as proposed by the International Regulatory Authorities for health drugs while the rest of metals, i.e., Zinc, Manganese, and Iron are within the therapeutic limits. (author)
Mahesh Kumar Harit
Full Text Available Cancer is a dreadful disease. Uncontrolled growth of cells is called Cancer. First cell is formed from sperm & ovum [Shukra & Shonit]. Controlled multiple division of this cell is result of individual’s body. If this division is uncontrolled, it is cause to create Cancer. Every divided cell is producing same type of new cells. If new cell is not as it is in comparison with mother cell, it can be called cancer. It is not a new disease, ancient text of Ayurved have definite references. In Ayurved, it is described as an Arbuda, Vidradhi, Granthi, Gulma, Shoth and Apachi etc. As per etiology of Ayurved Shoth is primary symptom of Cancer. Because of diminished Jatharagani and Dhatvagni aamotpati takes place. The sthanashanshraya stage is the base of uncontrolled growth. Specific Dhatvagnimandhya is result of specific dhatu’s abnormal vridhi or uncontrolled growth. According to Ayurvedic texts, cancer is a serious Dhatugat disease. So, shodhana chikitsa is required as per condition of disease and patient. Raktamokshan (Bloodletting, Shalya Karma (Surgery and Agnikarma (Heat Burn therapy are especially beneficial in this disease. Following drugs are useful for internal use – Kanchnar, Gokshure, Nirgundi, Punarnava, Bhumyamalaki, Bhalataka, Ashwagandha, Ahiphen, Rohitak, Hirak Bhasma, Suvarna Bhasma, Tamra Bhasma, Shringa Bhasma, Abhraka Bhasma etc. There is a definite need to use these drugs in various formulations to establish therapeutic efficacy to conquer this challenging disease.
Nhawkar Smita V*, Mullani Ashish K, Magdum Chandrakant S and D’Souza John I
Full Text Available Memorin is an ayurvedic remedy for improving mental function. Standardization of Ayurvedic formulations is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assurance program for production and manufacturing of herbal drugs. WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines as a prerequisite for global harmonization are of importance. The aim of present study is Quality standardization and toxicity study of Memorin. Standardization of drug was done on the basis of evaluating the drug for its Physico-chemical parameters and presence of phytochemical constituents. It include total ash value, extractive values, loss on drying, bulk density, tapped density etc. Drug was evaluated for presence of alkaloids, proteins, steroids, tannins, glycosides etc. Qualitative evaluation of the drug was performed by means of FT-IR, GC-MS and HPLC. In HPLC, C18 column was used. Flow rate was 1 ml/min. Mobile phase for HPLC analysis was methanol: ammonium acetate and it was run at 350nm for detection of compounds. Toxicity study of drug was done by using animals (Wistar albino rats. It can be conclude that the drug was safe and there was no sign of toxicity and mortality.
This paper is an attempt to understand the project of mainstreaming in India's health care system that has started with an aim to bring marginalized and alternative systems of medicine in mainstream. The project has gained much attention with the establishment of Department of Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy (AYUSH) in the year 2003, which is now a ministry. It has ushered some positive results in terms of growth of AYUSH hospitals and dispensaries. However, it has also raised challenges around the theory and practice of mainstreaming. With an emphasis on Ayurvedic practice in Delhi Government Health Institutions, this article has tried to analyze some of those challenges and intricacies. Drawing on Weber's theory of bureaucratization and Giddens's theory of structuration, the paper asks what happens to an alternative medical system when it becomes part of the bureaucratic set-up. Along with the questions of structures, it also tries to combine the question of the agency of both patients and doctors considered to be the cornerstone of the Ayurvedic medical system. Although our study recognizes some of the successes of the mainstreaming project, it also underlines the challenges and problems it faces by analyzing three points of view (institutions, doctors, and patients). PMID:27297512
Venkatasubramanian, Padma; Kumar, Subrahmanya K; Nair, Venugopalan S N
In the absence of a desired first choice medicinal herb, classical Ayurveda recommends use of a functionally similar substitute. Post 16th century Ayurvedic texts and lexicons give specific examples of possible substitutes. Here we report a preliminary study of one such Ayurvedic substitution pair: Musta (Cyperus rotundus L., Cyperaceae), a common weed, for the rare Himalayan species, Ativisha (Aconitum heterophyllum Wall. ex Royle; Ranunculaceae). The study's strategy was to use modern phytochemical and pharmacological methods to test the two herbs for biochemical and metabolic similarities and differences, and literary studies to compare their Ayurvedic properties, a novel trans-disciplinary approach. No previous scientific paper has compared the two herbs' bioactivities or chemical profiles. Despite being taxonomically unrelated, the first choice, but relatively unavailable (Abhava) plant, A. heterophyllum, and its substitute (Pratinidhi) C. rotundus, are not only similar in Ayurvedic pharmacology (Dravyaguna) profile, but also in phytochemical and anti-diarrheal properties. These observations indicate that Ayurveda may attach more importance to pharmacological properties of raw drugs than to their botanical classification. Further research into the nature of raw drugs named could open up new areas of medicinal plant classification, linking chemistry and bioactivity. Understanding the logic behind the Ayurvedic concept of Abhava Pratinidhi Dravya (drug substitution) could lead to new methods of identifying legitimate drug alternatives, and help solve industry's problems of crude drug shortage. PMID:21829299
Parul Agarwa; Bhawna Sharma; Amreen Fatima; Sanjay Kumar Jain
Convolvulus pluricaulis Choisy (C. pluricaulis) is a perennial herb that seems like morning glory. All parts of the herb are known to possess therapeutic benefits. The plant is used locally in Indian and Chinese medicine to cure various diseases. It is used in Ayurvedic formulation for chronic cough, sleeplessness, epilepsy, hallucinations, anxiety etc. Based on the comprehensive review of plant profile, pharmacognosy, phytochemistry, pharmacological and toxicological data on the C. pluricaulis, there will be more opportunities for the future research and development on the herb C. pluricaulis. Information on the C. pluricaulis was collected via electronic search (using Pub Med, SciFinder, Google Scholar and Web of Science) and library search for articles published in peer-reviewed journals. Furthermore, information also was obtained from some local books on ethnopharmacology. This paper covers the literature, primarily pharmacological, from 1985 to the end of 2012. The C. pluricaulis is an important indigenous medicine, which has a long medicinal application for liver disease, epileptic disease, microbial disease, cytotoxic and viral diseases, central nervous system (CNS) disease in Ayurvedic medicine, traditional Chinese medicine and other indigenous medical systems. The isolated metabolites and crude extract have exhibited a wide of in vitro and in vivo pharmacological effect, including CNS depression, anxiolytic, tranquillizing, antidepressant, antistress, neurodegenerative, antiamnesic, antioxidant, hypolipidemic, immunomodulatory, analgesic, antifungal, antibacterial, antidiabetic, antiulcer, anticatatonic, and cardiovascular activity. A chemical study of this plant was then initiated, which led to the isolation of carbohydrats, proteins, alkaloids, fatty acids, steroids, coumarins, flavanoids, and glycosides as active chemicals that bring about its biological effects. A series of pharmacognostical studies of this plant show that it is a herb, its stem and
Behere, Prakash B.; Das, Anweshak; Yadav, Richa; Behere, Aniruddh P.
The perfect balance of mind, body and soul is considered as complete health in Ayurveda. Ayurveda has its own identity as most ancient and traditional System of Medicine in India. Even Ayurveda emphasizes its treatment modalities into three parts viz. Satwawajay Chikitsa, Yuktivyapashray and Daivyapashray Chikitsa. Sattvavajaya therapy mentioned in Charakasamhita and it used as new concept of psychotherapy in Ayurveda. The effectiveness of “traditional mental health promoting practices” was i...
Patwardhan, Kishor; Gehlot, Sangeeta; Singh, Girish; Rathore, H. C. S.
In the present day scenario, Ayurveda is globally being perceived in several contradictory ways. Poor quality of Ayurveda graduates produced as a result of poorly structured and poorly regulated education system is at least one of the important factors responsible for this scenario. The present study was carried out to evaluate the ‘Global challenges of graduate level Ayurvedic education’ and is based on the responses of Ayurvedic students and Ayurvedic teachers from various educational insti...
Maciuk, Alexandre; Bouchet, Marie-Jeanne; Mazars, Guy; Um, B.H.; Anton, Robert
Introduction In modern books of ayurvedic Materia Medica plants are often classified into different groups according to their prabhâva or "specific action". The prabhâva corresponds broadly to the western concept of pharmacological action (Mazars, 1995). Plants considered having a nootropic effect belong to the medhyâ (intellect promoting) group (from Sanskrit "medhâ", intellect). They are used as stimulants for the central nervous system, to improve memory and attention, or against epilepsy ...
Ramesh, P R; Kumar, K S; Rajagopal, M R; Balachandran, P; Warrier, P K
Constipation is a frequent cause of distress in advanced cancer. A palliative care unit in Kerala, a southern state of India, conducted a controlled trial comparing a liquid Ayurvedic (herbal) preparation (Misrakasneham) with a conventional laxative tablet (Sofsena) in the management of opioid-induced constipation in patients with advanced cancer. Although there was no statistically significant difference in the apparent degree of laxative action between the two, the results indicate that the small volume of the drug required for effective laxative action, the tolerable taste, the once-daily dose, the acceptable side effect profile, and the low cost make Misrakasneham a good choice for prophylaxis in opioid-induced constipation. There is a need for further studies of Ayurvedic medicines in palliative care. PMID:9803051
Full Text Available Ovarian cysts are fluid filled sacs inside the ovary that are common among women during their reproductive years. Most cysts are harmless and go away without any treatment, but some may cause problems such as rupturing, bleeding, or pain; and surgery may be required to remove the cyst(s. When the follicles (sacs in the ovaries do not rupture, they form small cysts called 'simple cysts'. These form whenever ovary produces too much of estrogen hormone. 'Dermoid cysts' & 'chocolate cysts' are other types of cysts. 'Large' or 'pathological cysts' can occur in about 5% of women during their reproductive years. Management of Ovarian cyst through surgery is available to meet urgent medical need, but huge challenges remain to treat by medicines. Ayurveda, (the Science of Life which is the oldest well documented ancient Indian System of medicine is giving new ray of hope in the management of ovarian cyst (Kaphaj Granthi vikaar. This article presents a successfully managed case of ovarian cyst in the form of a case report by Ayurvedic treatment.
Rogers, Curtis R.
The Ayurvedic Institute, which has been licensed as a private institution of higher education in New Mexico since 1994, offers training in the traditional therapy of East Indian Ayurveda, which includes the use of herbs, nutrition, panchakarma cleansing, and accupressure massage. The institute also offers training in the related disciplines of…
Full Text Available Ayurvedic eye drops preparation contains aqueous extracts of different herbs. Ethnobotanical survey shows that plants used in Ayurvedic eye drops formulation are rich source of tannin and tannin like compounds. Antioxidant and antimicrobial properties of ayurvedic eye drops are attributed to the presence of tannins and tannin like compounds. Therefore in the present study an attempt has been made to determine the tannin content in some ayurvedic eye drops, by using Folin-Denis method. A blue colored complex is formed by using phosphotungustomolybdic acid. Estimation was done on UV/Vis spectrophotometer. The tannin content of all the three brands was found to be 420, 918 and 270.49 µg/ml. The results obtained are reproducible with coefficient of variation less than 1.0% . Hence the present approach can be used as one of the parameters for the standardization of ayurvedic eye drop preparations.
Full Text Available A 47 year old diabetic male patient was diagnosed and treated for high risk AML-M3 at Tata Memorial Hospital (BJ 17572, Mumbai in September 1995. His bone marrow aspiration cytology indicated 96% promyelocytes with abnormal forms, absence of lymphocytic series and myeloperoxide test 100% positive. Initially treated with ATRA, he achieved hematological remission on day 60, but cytogenetically the disease persisted. The patient received induction and consolidated chemotherapy with Daunorubicin and Cytarabine combination from 12.01.96 to 14.05.96, following which he achieved remission. However, his disease relapsed in February 97. The patient was given two cycles of chemotherapy with Idarubicine and Etoposide, after which he achieved remission. His disease again relapsed in December 97. The patient then refused more chemotherapy and volunteered for a pilot Ayurvedic study conducted by the Central Council for Research in Ayurveda and Siddha, New Delhi. The patient was treated with a proprietary Ayurvedic medicine Navajeevan, Kamadudha Rasa and Keharuba Pisti for one year. For the subsequent 5 years the patient received three months of intermittent Ayurvedic treatment every year. The patient achieved complete disease remission with the alternative treatment without any adverse side effects. The patient has so far completed 13 years of survival after the start of Ayurvedic therapy.
Full Text Available Any branch of science demands precision for its development, and so does the medical science. For precision facts, observations or measurements have to be expressed in a figure, which is termed as statistics. Everything in medicine be it a research, diagnosis or treatment, depends on numbers or measurement. Ayurvedic scholars had given due regard to the importance of statistical methods. The mentioning of term ‘sankhya’ and ‘maana’ in the literature of Ayurveda itself indicates the importance given to numbers and measurement. This work aims at interpreting different terminologies of Ayurveda from the Bio-statistical perspective. For this purpose relevant information were collected from the various literatures of Ayurveda and contemporary science and interpretation was done on each statistical terminology. The statistical methods which were used by the ancient Indian seers are in practice for a long time, but it is the need of the hour to explore them with some new terminologies of contemporary science, to standardize the quality of research in Ayurveda. Hence by this work it would be helpful to conclude that Statistical methods which is considered as a recent advancement was in use since ages.
Full Text Available Diseases caused by helminthes are quite common and comprise a very large group of infestations and infections in human beings. The Krimi Roga (worm infestation is one of the most common diseases found in paediatric practice. Helminthiasis is prevalent globally (1/3 of world’s population harbours them, but is more common in developing countries with poorer personal and environmental hygiene. In Vedic and Ayurvedic literatures, the word krimi is vague term used to denote tiny living being. Acharyas described krimis in various Samhitas in detail and they also believed that krimi also act as an etiological factor in various disease e.g. krimija shiorroga, hridaroga etc. Because of the fewer side effects, the importance of herbal drugs in remedy has tremendously increased in the recent years. A wide variety of plants possess narrow or broad spectrum anthelminthic activities which are naturally available.
Ayurvedic or herbal products being processed at ISOMED are primarily for microbiological upgradation and not necessarily for sterilization. These products must satisfy the microbiological requirements of the importing countries, besides, meeting physical and chemical parameters. Ethylene oxide (ETO) and gamma radiation are the obvious sterilants for the purpose. With more and more countries imposing restriction upon the use of ETO, gamma radiation is the preferred choice. Psyllium (Ispaghula) husk, garcina cambogia, various alkaloids, neem, tulsi etc. and their extracts and formulations are the principal products. Together they constitute roughly 2 to 2.5% of the total volume processed at ISOMED. The last year's figure ending Oct '01 was 3000 standard cartons or 270 cubic meter. (author)
Kumar, A; Nair, A G C; Reddy, A V R; Garg, A N
Bhasmas are unique Ayurvedic metallic preparations with herbal juices/fruits, known in the Indian subcontinent since the seventh century BC and widely recommended for treatment of a variety of chronic ailments. Twenty bhasmas based on calcium, iron, zinc, mercury, silver, potassium, arsenic, copper, tin, and gemstones were analyzed for up to 18 elements by instrumental neutron activation analysis, including their C, H, N, and S contents. In addition to the major constituent element found at % level, several other essential elements such as Na, K, Ca, Mg, V, Mn, Fe, Cu, and Zn have also been found in microg/g amounts and ultratrace (ng/g) amounts of Au and Co. These seem to remain chelated with organic ligands derived from medicinal herbs. The bhasmas are biologically produced nanoparticles and are taken along with milk, butter, honey, or ghee (a preparation from milk); thus, this makes these elements easily assimilable, eliminating their harmful effects and enhancing their biocompatibility. Siddha Makaradhwaja, a mercury preparation is found to be stoichiometrically HgS without any traces of any other element. Similarly, Swet Parpati is stoichiometrically KNO3 but is found to have Mn, Cu, Zn, Na, P, and Cl as well. An attempt has been made to correlate the metallic contents with their medicinal importance. Na and K, the two electrolytic elements, seem to be well correlated, although K/Na varies in a wide range from 0.06 to 95, with specifically low values for Ca-, Fe-, and Zn-based bhasmas. K/P also varies in a wide range from 0.23 to 12, although for most bhasmas (n = 12), it is 2.3 +/- 1.2. Further, Fe/Mn is linearly correlated (r = 0.96) with Fe in nine noniron bhasmas. PMID:16632893
Tiwari Radheyshyam; Reddy K.R.C; Gupta Sanjay; Tripathi J.S.
Saraswata Churna is a unique combination of Ayurvedic herbal drugs, containing mainly Medhya Rasayana drugs, like Vacha, Shankhpushpi, Aswagandha, Bramhi, etc. For the first time Saraswata churna is mentioned in Bhavaprakash Unmadadhikar and formula given in the same, selected for present study. The drug is prepared in the Ayurvedic Pharmacy, Institute of Medical Sciences, Banaras Hindu University and was selected for the management of Geriatric Depression. In the clinical study a series of 5...
Rao, Rammohan V.; Descamps, Olivier,; John, Varghese; Bredesen, Dale E.
Alzheimer's disease is an age-associated, irreversible, progressive neurodegenerative disease that is characterized by severe memory loss, unusual behavior, personality changes, and a decline in cognitive function. No cure for Alzheimer's exists, and the drugs currently available to treat the disease have limited effectiveness. It is believed that therapeutic intervention that could postpone the onset or progression of Alzheimer's disease would dramatically reduce the number of cases in the n...
Panigrahi Hemanta kumar
Full Text Available This interventional, quasi-experimental study (pre-post test design was conducted at Ayurveda Central Research Institute, New Delhi to study the efficacy of Leech Therapy along with some Ayurvedic medicine in vitiligo. Patients were selected by non-probability purposive sampling method after obtaining an informed consent. Twenty patients suffering from vitiligo (12 male and 08 female, aged more than 15 years and involving less than 25% of body surface area were enrolled. All the patients were kept in a single group. All the patients were called to OPD for Leech application once in a week. The patients were followed up weekly for first month and later on fortnightly for five months to monitor the improvement and adverse effects. The mean re-pigmentation achieved was 60 % (VASI score of 3.69, while the arrest of progression (stationary was noted in 35 % of patients. In 5% of patient it was spreading. We recommend that leech therapy along with internal administration of Ayurvedic medicine is effective in the treatment of Vitiligo.
Full Text Available Ayurveda is the ancient thought and treatise that deals with the knowledge of living a healthy life. There are several types of medicaments that are being used in the Ayurvedic mode of treatment. The source of these drugs is diverse and belongs to different category. The category ranges from plants and animals to minerals, and encircles around different types of species of plants and animals with vivid habitats.In the course of last thirty years, marine organisms have been proven to be a rich source of wide range of worthy compounds for medicine. In Ayurveda there is a wide range of marine drugs like Mukta, Varatika, Praval, Agnijvar, Samudra phena, etc that are useful in the management of numerous diseases like paralysis, hyperacidity, cancer, dyspepsia, eye diseases, etc. This review makes a humble effort to summarize and gather knowledge about different types of marine drugs that are described and explained in Ayurvedic system of medicine, its traditional processing and chemistry, ethno pharmacology and pharmacological role.
Jong Yeol Kim
Full Text Available Sasang constitutional medicine (SCM, traditional Chinese medicine (TCM and Ayurveda are three different forms of Asian traditional medicine. Although these traditions share a lot in common as holistic medicines, the different philosophical foundations found in each confer distinguishing attributes and unique qualities. SCM is based on a constitution-based approach, and is in this way relatively more similar to the Ayurvedic tradition than to the TCM, although many of the basic SCM theories were originally derived from TCM, a syndrome-based medicine. SCM and TCM use the same botanical materials that are distributed mainly in the East Asian region, but the basic principles of usage and the underlying rationale are completely different from each other. Meanwhile, the principles of the Ayurvedic use of botanical resources are very similar to those seen in SCM, but the medicinal herbs used in Ayurveda generally originate from the West Asian region which displays a different spectrum of flora.
Full Text Available Background: The treatment options for improving the balance in degenerative cerebellar ataxias are very few. Ayurvedic texts have described diverse treatment regimens for this disease. Aims: To determine the change in balance indices, if any, by dynamic posturography (Biodex Balance System, USA in progressive cerebellar ataxia following Ayurvedic treatment. Materials and Methods: We performed a preliminary open labelled study on ten patients diagnosed with progressive cerebellar ataxia. The patients were treated over a period of one month. Treatment consisted of Shirobasti (therapeutic retention of medicament over the scalp in male patients and Shirodhara (pouring of a steady stream of medicament on the forehead in female patients with Dhanvantaram tailam (medicated oil for 45 minutes daily, followed by Abhyanga (methodical massage with Dhanvantaram tailam and Bhashpa sweda (steam bath, for 14 days. In addition, the treatment also consisted Abhyantara aushadha (oral medicines of Maharasnadi kashayam 15ml thrice daily, Dhanvantaram capsules 101 two capsules thrice daily, and Ashwagandha tablet 500 mg one tablet thrice daily, for one month. The patients were assessed on the Biodex balance system before and after the treatment. Results were analyzed using paired samples ′t′ test. Results: All patients tolerated the treatment well without any adverse events and reported subjective improvement in walking. There was a statistically significant improvement in the overall and anteroposterior balance indices of dynamic stability. Conclusions: Over the short period of the present study, Ayurvedic therapy was found to be safe and, showed improvement in the balance in patients with progressive degenerative cerebellar ataxia. Further randomized placebo-control double-blind studies are needed to validate the results.
Ashok Kumar Panda
Results and Conclusion: We found that 36 species of orchids are used as medicines for different purposes of health. The botanical and ayurvedic name, phenology, parts used and medicinal uses of 36 orchids are presented in this paper along with its local distribution.
Anwesa Bag; Subir Kumar Bhattacharyya; Rabi Ranjan Chattopadhyay
Medicinal plants are part and parcel of human society to combat diseases from the dawn of civilization. Terminalia chebula Retz. (Fam. Combretaceae), is called the‘King of Medicine’ in Tibet and is always listed at the top of the list of ‘Ayurvedic Materia Medica’ because of its extraordinary power of healing. The whole plant possesses high medicinal value and traditionally used for the treatment of various ailments for human beings. Some of the folklore people used this plant in the treatment of asthma, sore throat, vomiting, hiccough, diarrhea, dysentery, bleeding piles, ulcers, gout, heart and bladder diseases. The plant has been demonstrated to possess multiple pharmacological and medicinal activities, such as antioxidant, antimicrobial, antidiabetic, hepatoprotective, anti-inflammatory, antimutagenic, antiproliferative, radioprotective, cardioprotective, antiarthritic, anticaries, gastrointestinal motility and wound healing activity. But no systematic updated information on the therapeutic effectiveness of Terminalia chebula, a popular herbal remedy in India and South-East Asia has so far been reported. This review highlights an updated information particularly on the phytochemistry and various pharmacological and medicinal properties of Terminalia chebula Retz. and some of its isolated compounds, along with their safety evaluation. This may provide incentive for proper evaluation of the plant as medicinal agent against the human diseases and also to bridge the lacunae in the existing literature and future scope which may offer immense opportunity for researchers engaged in validation of the traditional claims and development of safe and effective botanical medicine.
Full Text Available Buerger’s disease is a condition characterized by occlusive disease of small and medium sized arteries (planter, etc.. The first reported case of BUERGER’S DISEASE was described in Germany by Von Winiwarter in 1879. This disease involves small to medium sized arteries and veins of the upper and lower extremities. This disease is found more frequently in men between 20 – 40 years of age. It is very uncommon in women (male: female 3:1 who constitute only 5% -10% of all patients with buerger’s disease. This condition is strongly associated with smoking. In Ayurveda there is no clear cut evidence of buerger’s disease, but on the basis of its clinical presentation and pathogenesis, it can be correlated with vatarakta. Vatarakta is such a disease where simultaneously vata and rakta both are vitiated and vitiated vata obstructed the rakta vaha srota. Once localized ,it get associated with pitta causes respective affliction. Hence it produce pain mostly in respective joint and which is very difficult to tolerate. Symptoms which are found having predominance of vata , rakta , pitta, and kapha or in combination of two or three dosha. There is no such description available in ayurvedic text as BUERGER’S DISEASE but on the basis of pathogenesis, sign and symptoms this disease can be correlated with vata rakta vyadhi. Here vata and rakta plays a vital role for the production of the disease, keeping this view in mind we have started the following therapy and had got response. This is hypothesis that co relation buerger’s disease with gambhir vata rakta and treat accordingly which was describe in our classics.
Rajalakshmy M R
Full Text Available Water extraction is a major process in Ayurvedic medicine manufacturing industry. This process involves water extraction of huge quantity of herbs, which culminates in the generation of large amount of marc or herbal residue. Usually the residue is either incinerated or converted to herbal manure. This paper investigates the marc of Withania somnifera roots obtained from Ayurvedic Industry for presence of valuable and potent bioactive phytochemicals. The chances of the phytochemicals getting altered by the process of prolonged heating is also looked into and found that no such genesis or degradation of phytochemicals leading to a new compound has occurred in the marc. As part of study, physicochemical analysis such as total ash percentage, acid insoluble ash percentage and extractive values are performed. Preliminary phytochemical analysis was carried out with different extracts, like hexane, ethyl acetate and methanol of both herb and marc which showed the presence of similar compounds. High Performance Thin Layer Chromatography finger printing and densitogram of hexane, ethyl acetate and methanol extracts of marc and herb showed that there was a reduction in the concentration of the actives in marc. The densitogram of ethyl acetate extract showed absence of certain prominent peaks in marc. In the case of methanol extract the prominent peaks were present in the marc and the concentration of some major actives were reduced in the hexane extract of marc.
Full Text Available Gridhrasi (sciatica is one among Vata-vyadhi caused by aggravated Vata Doshas. It is characterized by burning, stinging or numbing pain that is felt in the buttock, thigh, leg or foot. It may or may not be associated with low back pain. Purpose of the study was to ameliorate the clinical manifestation of Gridhrasi. In this case report patient who suffered from Gridhrasi of the left leg since one year was treated with combined Ayurvedic regimen. Patrapinda Swedana for 21 days and Erandmuladi Niruhabasti as Karma Basti schedule were used as Panchakarma procedure. Ekangaveera Rasa 250mg B.D., Dasmoola Kwatha 40ml B.D., Ashwagandha Churna 3g B.D. and Triyodashanga Guggulu 2 Tablets B.D., were given for 1 month as oral medicine. Walking distance and SLR test were taken for assessment parameter, VAS score was adopted for pain. Before treatment patient was not able to walk even 4 to 5 steps due to severe pain and his SLR were 30⁰ of left side. After one month treatment he can walk up to 500 meters without any difficulty, SLR was changed to 90⁰ and patient had got 75% relief in pain. This case report showed that combined Ayurvedic regimen is potent and safe in the treatment of Gridhrasi.
V. S. Kulkarni
Full Text Available Trikatu churna is one of the commonly used Ayurvedic formulations in the traditional system of medicine in India for the treatment of agnimandya, i.e. anorexia. Trikatu contains equal amounts of finely powdered rhizomes of Zingiber officinale Roscoe (Zingiberaceae and fruits of Piper longum L. and Piper nigrum L. (Piperaceae. The chief objective of the study was to determine the antianorectic effects of three drugs individually and to compare these effects with the effect of Trikatu. The activity of the drugs was studied after anorexia was induced in rats by (1 physical stress arising from immobilization for 60 min; (2 intraperitoneal injection of Escherichia coli lipopolysaccharide (LPS, 100 μg/kg body weight; and (3 intraperitoneal administration of fluoxetine (8 mg/kg body weight. Similar doses of the extracts were tested on freely feeding rats and on rats that had been deprived of food for 20 h. Corticotrophin-releasing factor (CRF, 0.3 μg/rat can induce anxiogenic-like behavior and reduced food intake. This model was also studied, and the results were compared. The components of Trikatu churna failed to individually reverse the inhibition of feeding. In contrast, Trikatu churna pretreatment reversed stress-, fluoxetine- and CRF-induced anorexia. The study provides strong evidence of the synergistic action of Ayurvedic formulas and also proves the ability of Trikatu churna to reduce stress and CRF-induced anorexia.
The paper discusses the many forms and representations of cyavanaprāsh, Ayurveda's best-selling medicine, already mentioned in Caraka's Compendium (c. 200 CE). The medicine's compositions, applications, and meanings, change over time and from locality to locality. Cyavanaprāsh is, for example, a patriotic formula, a booster of the immune system, a modern geriatric drug, and one of the elements in canonical Ayurvedic treatments. In the beginning of the 19th century cyavanaprāsh was a patriotic formula for fortifying Indian bodies and the nascent Indian nation. Nowadays the medicine is a Fast Moving Consumer Good (FMCG) and a money maker for Dabur India Ltd., the world largest Ayurvedic manufacturer. Instead of vitalising the nation its consumption now promises to make urban middle class consumers effectively modern. Branding and modern science must make Dabur Chyawanprash attractive in the eyes of these consumers. Ayurveda and cyavanaprāsh are also part of a global counter culture marked by neo-Orientalism and Ayurvedic medicines as facilitators of spirituality. The marketing of cyavanaprāsh by India's largest Ayurvedic manufacturer is used as a case study for discussing the proliferation of Ayurvedic brands and its critics. The imaging of Ayurvedic brands such as Dabur Chyawanprash threatens to obscure the fact that Ayurveda represents a unique way of looking upon health, disease and the human body. The proliferation of brands also makes Ayurvedic medicines more expensive and puts pressure on the natural environment as the main supplier of Ayurvedic ingredients. PMID:25639150
V. M. Shinde
Full Text Available In this study, the RAPD (Random Amplified Polymorphic DNA technique was employed for determination of the components in an Ayurvedic herbal prescription, Rasayana Churna. One-hundred-and-twenty decamer oligonucleotide primers were screened in the RAPD analysis to identify three Ayurvedic medicines, dried stem of Tinospora cordifolia, dried fruit of Emblica officinalis and dried fruit of Tribulus terestris, the Ayurvedic prescription. Primer OPC-6 simultaneously generated three distinct amplicons, each specific to one component. The marker with 600 bp is specific to Tinospora cordifolia; the marker 500 bp is specific to Emblica officinalis and the remaining marker >1000 bp was present in Tribulus terestris. Presence of three herbal medicines was determined when RAPD reaction with OPC-6 was performed. The technique was proved to contribute to the identification of components in Ayurvedic herbal preparation and thus helping to serve as a complementary tool for quality control.
Panikar, K. R.; Bhanumathy, P.; P. N. Raghunath
An ayurvedic oil preparation containing flowers of ixora coccinea and cortus sativum was subjected to an animal experimentation to find out how far it is efficient in preventing the development of Dalton's lymphoma as solid tumour. The oil was applied after injecting the cells and we found it could retard the development of tumour and arrest further development of already formed tumour.
Ukani, M.D.; Nanavati, D.D.; Mehta, N.K
Gokhshura (Tribulus Linn) of Family Zygophyllaceae is an indigenous plant which has been mentioned in Ayurveda with several clinical properties. The plant finds use in one form or the other in various ayurvedic preparations and this has been made it necessary to review the various studies carried out in its chemistry as well as pharmacology.
Full Text Available A new gas chromatographic-flame ionization detector (GC-FID method was developed for quantification of ayurvedic polyherbal formulation. The GC-FID method was found highly accurate, sensitive, simple and precise. This method was validated as per international conference on harmonization (ICH guidelines. Experimental work was performed by nonpolar capillary column (Zb-5, 5%-Phenyl-95%-dimethylpolysiloxane. Film thickness of capillary column (Zb-5 was (0.25 μm and length 30 m × 0.25 mm i.d. The temperature of the oven, injector and detector were 200, 210 and 280°C respectively. Data processing system was applied to obtain data. The standards and test samples were prepared in absolute ethanol. The principle constituents t-Anethol, d-Limonene, cuminaldehyde and thymol were found in ayurvedic polyherbal formulation. The ICH validation parameters for the proposed procedure, recovery (limit 98.85-100.76%, precision (<1.00%, limits of detection, limits of quantification and linearity (r2 = 0.995 ± 0.002 were observed under acceptance limit. Validation results were statistically calculated. The result shows that method is selective and reproducible for quantification of ayurvedic polyherbal formulation. The presented GC method can be applied for the routine analysis of principle constituents as well as ayurvedic polyherbal formulation.
Shivamurthy, Raghu Prasada M.; Ravindra Kallappa; Shashikala G.H Reddy; Rangappa, Druva Kumar B.
Steven–Johnson syndrome may be considered as a cytotoxic immune reaction to drugs, infections etc. This is a case report of Steven–Johnson syndrome due to an ayurvedic preparation which was used in the treatment of mental retardation in a young girl.
Hema Sharma Datta; Rangesh Paramesh
The association between Ayurveda, anti-aging and cosmeceuticals is gaining importance in the beauty, health and wellness sector. Ayurvedic cosmeceuticals date back to the Indus Valley Civilization. Modern research trends mainly revolve around principles of anti-aging activity described in Ayurveda: Vayasthapana (age defying), Varnya (brighten skin-glow), Sandhaniya (cell regeneration), Vranaropana (healing), Tvachya (nurturing), Shothahara (anti-inflammatory), Tvachagnivardhani (strengthening...
Vineeta Khanvilkar; Leena Patil; Vilasrao Kadam
Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of drugs. World health organization (WHO) in 1999 has given a detail protocol for the standardization of herbal drugs comprising of a single content but very little literature is available for the standardization of polyherbal formulations. Chitrakadi Vati is official in ayurvedic formulary of India and it is prescribed for the treatment of irritable bowel syndrome, rheumatoid arthri...
Kulshrestha Mayank Krishna; Karbhal Kamleshwar Singh
Kapardika (Cypraea moneta Linn.) are the choice of drug for many indications in Ayurvedic practice. These are the sea products and obtained from seacoast. These were once used for playing purpose by children, ornamental purpose by women and used as money unit since ancient time. Literatures of ancient science and current available materials are reviewed to highlight the importance of Kapardika. This literary information may serve as an evidence to establish current research in ancient Ayurve...
Vinjamury, Sivarama Prasad; Vinjamury, Manjusha; der Martirosian, Claudia; Miller, Judith
Background: Insomnia is one of the most common complaints faced by primary care practitioners after pain. Non-pharmacological management of Insomnia that is noninvasive is gaining interest among patients with insomnia. Purpose: To determine the feasibility of recruiting and retaining participants in a clinical trial on shirodhara, Ayurvedic oil dripping therapy, for insomnia in the United States and also to investigate the therapeutic usefulness of Shirodhara for insomnia using standardized o...
Gupta, Mradu; Shaw, B. P; Mukherjee, A.
The aqueous extract of Jwarhar mahakashay Ayurvedic preparation (from the roots of Hemidesmus indicus R. Br., Rubia cordifolia L., Cissampelos pareira L.; fruits of Terminalia chebula Retz., Emblica officinalis Gaertn., Terminalia bellirica Roxb., Vitis vinifera L., Grewia asiatica L., Salvadora persica L. and granules of Saccharum officinarum L.) has been used as a traditional antipyretic. Experimental studies confirmed its antipyretic–analgesic effect with very low ulcerogenicity and toxici...
Pillai, Divya; Pandita, Nancy
Draksharishta is an ayurvedic polyherbal formulation is prescribed for digestive impairment, respiratory disorders and weakness. Though the formula composition and therapeutic claims of draksharishta are part of the Ayurvedic Formulary of India, the scientific methods for its quality and safety evaluation are yet to be documented. The current work is an attempt to evaluate the quality parameters of draksharishta which has been checked vis a vis herbs used in the formulation by modern scientific control procedures like macroscopic and microscopic study, physico-chemical analysis, preliminary phytochemical analysis, thin layer chromatography and high performance thin layer chromatography to fix the quality standard of this formulation with reference to two marketed formulations i.e. M1 and M2, respectively. The quality control parameters were within the limit as per the Ayurvedic Pharmacopeia of India which signifies good quality and purity of the plant materials. Thin layer chromatography profiles showed the presence of gallic acid, catechin and resveratrol and further it was confirmed by HPTLC fingerprints. The results obtained can be used by pharmaceutical companies as quality control parameters in order to have a proper quality check during processing. PMID:27168691
Pillai, Divya; Pandita, Nancy
Draksharishta is an ayurvedic polyherbal formulation is prescribed for digestive impairment, respiratory disorders and weakness. Though the formula composition and therapeutic claims of draksharishta are part of the Ayurvedic Formulary of India, the scientific methods for its quality and safety evaluation are yet to be documented. The current work is an attempt to evaluate the quality parameters of draksharishta which has been checked vis a vis herbs used in the formulation by modern scientific control procedures like macroscopic and microscopic study, physico-chemical analysis, preliminary phytochemical analysis, thin layer chromatography and high performance thin layer chromatography to fix the quality standard of this formulation with reference to two marketed formulations i.e. M1 and M2, respectively. The quality control parameters were within the limit as per the Ayurvedic Pharmacopeia of India which signifies good quality and purity of the plant materials. Thin layer chromatography profiles showed the presence of gallic acid, catechin and resveratrol and further it was confirmed by HPTLC fingerprints. The results obtained can be used by pharmaceutical companies as quality control parameters in order to have a proper quality check during processing.
Kulkarni, Santosh S.
The Metals and Minerals are heavy, nonabsorbable and toxic substances. Metals are used as medicines in Ayurveda since from Samhita period in the fine powder form named as ‘Ayaskriti’1. Latter with the development of ‘Marana’ technique (7th Cent AD) the Metals and Minerals are converted in to very very fine and absorbable, therapeutically most effective and least or Nontoxic form of Medicines known as ‘Bhasma’2. According to Ayurvedic concept the change in the qualities is due to ‘Samskara’ do...
De Silva R.H.S.K.
Full Text Available Ayurveda is one of the oldest medical systems in the world. Health is a state of equilibrium of Physical, Psychological and Spiritual components. This equilibrium is maintained between internal and external environment which is known as Loka Purusa Samya. Ayurvedic therapeutics uses herbs and minerals extracted from environment to maintain the well being of human being. Universally this unique feature ensured sustainable utilization of both environmental and Ayurvedic principles in providing health care. Recently, mankind’s attitude towards the environment has changed with new concepts such as Sustainable Development, Cleaner Production Technology and Environmental Valuation Techniques etc; Increased knowledge and awareness of environmental goods & services, global attention is oriented towards Ayurvedic Medicine.Due to this resurgence, economic value of Ayurvedic Medicine in the global market is at a peak level. Our focus is on the evaluation of Total Economic Value (TEV of Ayurvedic Medicine with reference to Environmental Valuation Techniques (EVT. Revealed Preference (RP and Stated Preference (SP EVT are clearly described. Some critical points of Hedonic Pricing, Travel Cost and Benefit Transfer Methods of RP and Contingent Valuation and Choice modeling Methods of SP were outlined with demonstrative examples related to Ayurveda according to their markets. This paper will be helpful to identify the TEV of Ayurvedic Medicine. Moreover, it explores a new area of study for further research and development to overcome the issues relating to globalization of Ayurveda.
Payyappallimana, Unnikrishnan; Venkatasubramanian, Padma
Ayurveda, a traditional system of medicine that originated over three millennia ago in the South Asian region, offers extensive insights about food and health based on certain unique conceptual as well as theoretical positions. Health is defined as a state of equilibrium with one’s self (svasthya) but which is inextricably linked to the environment. Ayurvedic principles, such as the tridosa (three humors) theory, provide the relationship between the microcosm and the macrocosm that can be applied in day-to-day practice. Classical Ayurveda texts cover an array of themes on food ranging from diversity of natural sources, their properties in relation to seasons and places and to their specific function both in physiological and pathological states. The epistemic perspective on health and nutrition in Ayurveda is very different from that of biomedicine and modern nutrition. However, contemporary knowledge is reinventing and advancing several of these concepts in an era of systems biology, personalized medicine, and the broader context of a more holistic transition in sciences in general. Trans-disciplinary research could be important not only for pushing the boundaries of food and health sciences but also for providing practical solutions for contemporary health conditions. This article briefly reviews the parallels in Ayurveda and biomedicine and draws attention to the need for a deeper engagement with traditional knowledge systems, such as Ayurveda. It points out that recreation of the methodologies that enabled the holistic view point about health in Ayurveda may unravel some of the complex connections with Nature. PMID:27066472
Nair, K. Vasudevan; Gopakumar, K.; Yoganarasimhan, S. N.; Shantha, T. R.; Keshavamurthy, K. R.
Details on 33 plants / drugs belonging to 30 genera and 22 families are provided in this paper; ayurvedic drug name, botanical sources in the island, short description of the species occurring in the islands, chemical constituents, ayurvedic preparations and therapeutic properties are elucidated. PMID:22557524
Nair, K. Vasudevan; Gopakumar, K.; Yoganarasimhan, S.N.; Shantha, T. R.; Keshavamurthy, K.R.
Details on 33 plants / drugs belonging to 30 genera and 22 families are provided in this paper; ayurvedic drug name, botanical sources in the island, short description of the species occurring in the islands, chemical constituents, ayurvedic preparations and therapeutic properties are elucidated.
Full Text Available Background & objectives: In the traditional system of medicine in India Ashwagandha powder and Sidh Makardhwaj have been used for the treatment of rheumatoid arthritis. However, safety and efficacy of this treatment have not been evaluated. Therefore, the present study was carried out to evaluate the efficacy and safety of Ayurvedic treatment (Ashwagandha powder and Sidh Makardhwaj in patients with rheumatoid arthritis. Methods: One hundred and twenty five patients with joint pain were screened at an Ayurvedic hospital in New Delhi, India. Eighty six patients satisfied inclusion criteria and were included in the study. Detailed medical history and physical examination were recorded. Patients took 5g of Ashwagandha powder twice a day for three weeks with lukewarm water or milk. Sidh Makardhwaj (100 mg with honey was administered daily for the next four weeks. The follow up of patients was carried out every two weeks. The primary efficacy end point was based on American College of Rheumatology (ACR 20 response. Secondary end points were ACR50, ACR70 responses, change from baseline in disease activity score (DAS 28 score and ACR parameters. Safety assessments were hepatic function [alanine aminotransferase (ALT, aspartate aminotransferase (AST, alkaline phosphatase (ALP, bilirubin and ß2 microglobulin], renal function (urea and creatinine and NGAL tests and urine mercury level. Results: The study was completed by 90.7 per cent (78/86 patients. Patients with moderate and high disease activity were 57.7 per cent (45/78 and 42.3 per cent (33/78, respectively. All patients were tested positive for rheumatoid factor and increased ESR level. Ashwagandha and Sidh Makardhwaj treatment decreased RA factor. A significant change in post-treatment scores of tender joint counts, swollen joint counts, physician global assessment score, patient global assessment score, pain assessment score, patient self assessed disability index score and ESR level were
Full Text Available Background: Tuberculosis is a global public health crisis. 25% of world's TB cases are found in India. Ayurveda, an ancient medical science may offer some solution to this problem hence a systematic review was carried out to assess the role of Ayurveda for the management of Tuberculosis. Methodology: A systematic review was carried out using published literature obtained through and ldquo;PUBMED and rdquo; till April 2015. The key words used for literature search include and ldquo;Ayurveda, role and Tuberculosis and rdquo;. Results and Discussion: It was observed that a couple of single and compound drugs have been used for the management of tuberculosis. However none of the studies could reflect the true anti-tubercular activities of any drug, both single and compound. Two of the studies revealed in vitro anti-tubercular properties of some herbs which can potentially be brought in to the realm of clinical trial to test their efficacy in human subject. Most of these Ayurvedic therapeutic preparations studied at different clinical settings primarily reflected their adjunct properties for the management of Tuberculosis. These studies revealed that Ayurvedic therapeutics were able to reduce associated symptoms and the adverse drug effects of ATDs (Antitubercular Drugs. Furthermore some of the preparations showed potential hepato-protective properties that can be simultaneously administered with ATDs. Conclusion: Distressingly research on the role of Ayurveda in the management of Tuberculosis is very scanty and mostly limited to adjunct or supportive therapy. Being a global public health crisis, it is highly recommended to carry out clinical trials on Tuberculosis patients by using Ayurvedic drugs and therapeutic regimens. [J Intercult Ethnopharmacol 2016; 5(1.000: 86-91
Virupaksha, Gupta K L; Kumar, Neeraj
Tarakeshwara Rasa (TR) is an Ayurvedic herbomineral compound formulation used in the intervention of Prameha vis-à-vis diabetes mellitus. The present study was executed to establish a fingerprint for this unique formulation, which can be adopted by the Ayurvedic pharmacies for drug standardization. TR is a formulation prepared by the trituration of four ingredients Abhraka Bhasma (AB), Loha Bhasma (LB), Vanga Bhasma (VB) and Rasa Sindhura (RS) in equal quantities with honey for one day. Each of the ingredients were prepared according to the norms of Ayurvedic classical texts and by employing Electric Muffle Furnace as heating device for incineration. To ensure the proper preparation of Bhasmas, standard tests (Bhasma Pariksha) were employed. After Bhasma complies these tests, TR was prepared and subjected for qualitative analysis, X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) studies. LB, AB, VB, RS and TR were also studied for free metal presence by employing phosphomolybdic acid. Chemical analysis of TR reveals that it contains Fe, Sn, Hg, Al, Mn, Ca and Mg. XRD study indicates that TR contains Fe2O3 (maghamite) in major phase and SnO2 (cassiterite), HgS, SiO2, HgO in minor phases. SEM study revealed that the compound is an agglomeration of particles. The particle size was in between 0.5 and 2 μ. Free metal detection by phosphomolybdic acid revealed the absence of free metals in the final Bhasmas. This is the first study establishing the characterization of Tarakeshwara Rasa. PMID:23723650
Singh, Sarvesh Kumar; Rajoria, Kshipra
Spinocerebellar ataxia -2 is a progressive, degenerative genetic disease caused by an expanded (CAG) trinucleotide repetition on the chromosome 12 resulting in production of an abnormal protein called ataxin-2. There is no known effective management or cure in biomedicine for this genetic disease. In the present study a case of SCA2 that was treated with Ayurvedic intervention is reported. Ayurvedic treatments in this case were directed towards alleviating symptoms and to reduce severe disability due to progressive nature of disease. A 42 year old male patient was diagnosed for Vāta vyādhi (group of various neurological disorders) and was- treated with Śālisastika pinda svedana (sudation with bolus of medicated cooked rice) for 30 days-, Śirobasti (sudation of head with the help of a cap on head) with Aśvagandhā taila for 45 days and Balādi ksīra basti (enema with medicated milk) with Aśvagandhā taila anuvāsana (enema with oil) for 30 days in Karma basti krama (30 days regime of purification and oleation enema) along with a combination of Ayurvedic oral drugs which consisted of Brahadvātacintāmanirasa – 125 mg, Vasantāmaltī rasa- 125 mg, Daśamūla kvātha- 40 ml, Aśvagandhā cūrṇa (powder of Withania somnifera DUNAL)- 3g, Amrtā cūrṇa (powder of Tinospora cordifolia Willd.)- 500 mg, Muktāśukti pisti – 500 mg, Yogarāja Guggulu – 500 mg twice a day for 2 months. Patient's condition was assessed on the Scale for Assessment and Rating of Ataxia (SARA). Before treatment, mean SARA score was 35. This reduced to 15 after treatment. Good relief in dysarthria, fasciculation, heaviness in eye, blurred vision, axial tremor; constipation and quality of life were observed in this case.
Singh, Sarvesh Kumar; Rajoria, Kshipra
Spinocerebellar ataxia -2 is a progressive, degenerative genetic disease caused by an expanded (CAG) trinucleotide repetition on the chromosome 12 resulting in production of an abnormal protein called ataxin-2. There is no known effective management or cure in biomedicine for this genetic disease. In the present study a case of SCA2 that was treated with Ayurvedic intervention is reported. Ayurvedic treatments in this case were directed towards alleviating symptoms and to reduce severe disability due to progressive nature of disease. A 42 year old male patient was diagnosed for Vāta vyādhi (group of various neurological disorders) and was- treated with Śālisastika pinda svedana (sudation with bolus of medicated cooked rice) for 30 days-, Śirobasti (sudation of head with the help of a cap on head) with Aśvagandhā taila for 45 days and Balādi ksīra basti (enema with medicated milk) with Aśvagandhā taila anuvāsana (enema with oil) for 30 days in Karma basti krama (30 days regime of purification and oleation enema) along with a combination of Ayurvedic oral drugs which consisted of Brahadvātacintāmanirasa - 125 mg, Vasantāmaltī rasa- 125 mg, Daśamūla kvātha- 40 ml, Aśvagandhā cūrṇa (powder of Withania somnifera DUNAL)- 3g, Amrtā cūrṇa (powder of Tinospora cordifolia Willd.)- 500 mg, Muktāśukti pisti - 500 mg, Yogarāja Guggulu - 500 mg twice a day for 2 months. Patient's condition was assessed on the Scale for Assessment and Rating of Ataxia (SARA). Before treatment, mean SARA score was 35. This reduced to 15 after treatment. Good relief in dysarthria, fasciculation, heaviness in eye, blurred vision, axial tremor; constipation and quality of life were observed in this case. PMID:27143801
Sarvesh Kumar Singh
Full Text Available Spinocerebellar ataxia -2 is a progressive, degenerative genetic disease caused by an expanded (CAG trinucleotide repetition on the chromosome 12 resulting in production of an abnormal protein called ataxin-2. There is no known effective management or cure in biomedicine for this genetic disease. In the present study a case of SCA2 that was treated with Ayurvedic intervention is reported. Ayurvedic treatments in this case were directed towards alleviating symptoms and to reduce severe disability due to progressive nature of disease. A 42 year old male patient was diagnosed for Vāta vyādhi (group of various neurological disorders and was- treated with Śālisastika pinda svedana (sudation with bolus of medicated cooked rice for 30 days-, Śirobasti(sudation of head with the help of a cap on head with Aśvagandhā taila for 45 days and Balaādi ksiāra basti (enema with medicated milk with Aśvagandhā taila anuvaāsana(enema with oil for 30 days in Karma basti krama(30 days regime of purification and oleation enema along with a combination of Ayurvedic oral drugs which consisted of Brahadvaātacintaāmanirasa – 125 mg, Vasantaāmaltiā rasa- 125 mg, Daśamūla kvātha- 40 ml, Aśvagandhā cūrṃa(powder of Withania somnifera DUNAL- 3g, Amrtaā cūrṃa (powder of Tinospora cordifolia Willd.- 500 mg, Muktāśukti pisti – 500 mg, Yogaraāja Guggulu – 500 mg twice a day for 2 months. Patient's condition was assessed on the Scale for Assessment and Rating of Ataxia (SARA. Before treatment, mean SARA score was 35. This reduced to 15 after treatment. Good relief in dysarthria, fasciculation, heaviness in eye, blurred vision, axial tremor; constipation and quality of life were observed in this case.
Full Text Available Background: Grahaṇimihira tailam is an unexplored ayurvedic oil preparation which consists of 34 ingredients. The efficacy of this traditional ayurvedic medicine is undisputable. Proper clinical standardization of this formulation will go a long way in securing greater recognition for it. The main objective of this study was to develop standardization parameters for the formulation in a multidisciplinary way. Materials and Methods: A simple and efficient method for the quantification of umbelliferone by high performance thin layer chromatography was developed and validated. Presence of the major fatty acids and their percentage were assessed by using gas chromatography-mass spectrometry (GC-MS. Various physio-chemical parameters, microbiological load, aflatoxins and mineral oil were also evaluated. Spread plate method was used for checking microbial contamination. Results: The results were validated as per standard protocols. Quantitative estimation revealed the percentage of umbelliferone to be in the range of 0.88-0.98 (w/w. GC-MS analysis of sample led to the identification of 14 fatty acids, in which linoleic acid was obtained as the major fatty acid. Microbes, aflatoxins and mineral oils were found to be absent in the tailam. Conclusion: The results which give the quantitative estimates of various physico-chemical parameters can be adopted to establish new standards for analysis of batch-to-batch variation and this data will facilitate shelf life studies in the future.
Hema Sharma Datta
Full Text Available The association between Ayurveda, anti-aging and cosmeceuticals is gaining importance in the beauty, health and wellness sector. Ayurvedic cosmeceuticals date back to the Indus Valley Civilization. Modern research trends mainly revolve around principles of anti-aging activity described in Ayurveda: Vayasthapana (age defying, Varnya (brighten skin-glow, Sandhaniya (cell regeneration, Vranaropana (healing, Tvachya (nurturing, Shothahara (anti-inflammatory, Tvachagnivardhani (strengthening skin metabolism and Tvagrasayana (retarding aging. Many rasayana plants such as Emblica officinalis (Amla and Centella asiatica (Gotukola are extensively used.
Thankamma, A.; Radhika, L.G.; Soudamini, C.
Methods were evolved for the detection of Curcuma longa in ayurvedic preparations. A simple method was also found out for the estimation of Curcuma longa in Vachalasunyadhi Taila using the formula –a = b/.32. Where a is the actual weight of Curcuma longa in Vilupatra Tailam and b is the weight obtained from graph of concentration of Curcuma longa VS OD. The methods evolved are so simple that it does not require any sophisticated instruments and hence it can be carried out in any quality contr...
Datta, Hema Sharma; Paramesh, Rangesh
The association between Ayurveda, anti-aging and cosmeceuticals is gaining importance in the beauty, health and wellness sector. Ayurvedic cosmeceuticals date back to the Indus Valley Civilization. Modern research trends mainly revolve around principles of anti-aging activity described in Ayurveda: Vayasthapana (age defying), Varnya (brighten skin-glow), Sandhaniya (cell regeneration), Vranaropana (healing), Tvachya (nurturing), Shothahara (anti-inflammatory), Tvachagnivardhani (strengthening skin metabolism) and Tvagrasayana (retarding aging). Many rasayana plants such as Emblica officinalis (Amla) and Centella asiatica (Gotukola) are extensively used. PMID:21836797
Full Text Available Saraswata Churna is a unique combination of Ayurvedic herbal drugs, containing mainly Medhya Rasayana drugs, like Vacha, Shankhpushpi, Aswagandha, Bramhi, etc. For the first time Saraswata churna is mentioned in Bhavaprakash Unmadadhikar and formula given in the same, selected for present study. The drug is prepared in the Ayurvedic Pharmacy, Institute of Medical Sciences, Banaras Hindu University and was selected for the management of Geriatric Depression. In the clinical study a series of 50 patients of Geriatric Depression were recruited randomly, based on the DSM-IV-TR diagnostic criteria of depression along with their screening for the level of depression using Geriatric Depression Scale (GDS-30. Out of 50, 30 patients were put on Saraswata Churna (Group-A, and 20 patients were on control group, Citalopram (Group-B. The total duration of therapeutic trial was three months. Hamilton Depression Rating Scale (HDRS has been used to evaluate the response of the drugs. Certain basic biochemical and hematological investigations were also measured before and after the trial. The results have been found to be encouraging with significant relief in the patients belonging to ‘group A’ with no side effects.
Shilpa, S; Venkatesha Murthy, C G
The study of personality has fascinated psychologists since a long time. Personality as an area of study has grown so much that a wealth of literature is available. On the other hand, the socio-ethnic dynamics of human race in the emerging global village context provoking psychologists to develop a personality theory which can treat certain basic components of personality as invariants, so that irrespective of culture, race, and nativity could still be able to study personality which will have universal applicability and relevance, is still far away. In the above emerging backdrop, "Ayurveda" has perhaps an important role to play as it can enable providing a theoretical and empirical base of personality traits and types. These Ayurvedic concepts are applicable to all human beings irrespective of caste, color, sex or race. Therefore, it is interesting to build on the Ayurvedic knowledge which has already given us so much since time immemorial, and validate some of these issues related to personality from psychological perspective. There are already certain efforts in understanding Sattva, Rajas, and Tamas Gunas. It can be furthered so that a comprehensive personality picture can be generated, which can have implications for health, career, education and many other dimensions of life. The present paper is a theoretical attempt in developing such a personality proposition which can be validated. Thus, the present paper only builds a theoretical framework for their possible empirical validity. PMID:22131752
This paper presents a method for identification of medicinal plants based on some important features extracted from its leaf images. Medicinal plants are the essential aspects of ayurvedic system of medicine. The leaf extracts of many medicinal plants can cure various diseases and have become alternate for allopathic medicinal system now a days. Hence this paper presents an approach where the plant isidentified based on its leaf features such as area, color histogram and edge histogram. Exper...
Fazlin Mohd Fauzi
Full Text Available In this article, we discuss our recent work in elucidating the mode-of-action of compounds used in traditional medicine including Ayurvedic medicine. Using computational (′in silico′ approach, we predict potential targets for Ayurvedic anti-cancer compounds, obtained from the Indian Plant Anticancer Database given its chemical structure. In our analysis, we observed that: (i the targets predicted can be connected to cancer pathogenesis i.e. steroid-5-alpha reductase 1 and 2 and estrogen receptor-β, and (ii predominantly hormone-dependent cancer targets were predicted for the anti-cancer compounds. Through the use of our in silico target prediction, we conclude that understanding how traditional medicine such as Ayurveda work through linking with the ′western′ understanding of chemistry and protein targets can be a fruitful avenue in addition to bridging the gap between the two different schools of thinking. Given that compounds used in Ayurveda have been tested and used for thousands of years (although not in the same approach as Western medicine, they can potentially be developed into potential new drugs. Hence, to further advance the case of Ayurvedic medicine, we put forward some suggestions namely: (a employing and integrating novel analytical methods given the advancements of ′omics′ and (b sharing experimental data and clinical results on studies done on Ayurvedic compounds in an easy and accessible way.
Scared Tulasi (Ocimum sanctum L.) of family Lamiaceae is a wonder ayurvedic herb which is known for its tremendous medicinal properties both in traditional folklore as well as pharmacological system of medicines. Every part of the plant finds its use in one form or the other. Keeping in view the importance of the plant, an attempt has been made to review the various studies carried out in traditional system of medicine as well as modern pharmacological investigations.
Patil Y. R.
Full Text Available Nasa (Nose is considered as one among the panchagnanendriya, whose functions are not only limited to olfaction and respiration but also considered as a pathway for drug administration. Since it is described as nose is the gateway for the shiras. Nasya karma is the special procedure where the drug is administered through that gateway. The medicine that is put into nostril moves in the channels & shows influence on shiras by removing out the accumulated doshas localized in shiras i.e., from all sinuses in the skull. In ayurvedic texts Pratimarsha, a type of Nasya is indicated as a daily regimen to keep maintain health of Nasal passage. ‘Anu Tailam’ is classical oil, indicated in Ashtang Hridaya (an authoritative text for various disorders of head, eyes, nose, ears and graying of hair. An open-label, placebo controlled, prospective, interventional, and exploratory clinical trial was carried out to evaluate the preventive effects of Anu Tailam. Experimental & placebo group contains 20 volunteers. Administration of Nasya therapy with “Anu tailam” for 30 days showed significant results on symptoms like tiredness, intensity of eyesight, capacity of senses, premature graying of hair, skin complexion. No considerable results obtained in placebo group.
Full Text Available Context: Ayurveda has abundant collection of effective formulations against diseases. In the era of increasing demand for indigenous medicines, maintaining quality standards is the need of the hour. Standardisation of compound formulations is lagging behind because of absence of reference standards. Lots of single and compound drugs have been described in Ayurvedic classics. Asanadi gana (Astanga Hridaya Sutrasthana 15 has kapha-medohara (pacifying Kapha and fat and lekhana (scraping property. Aims: The present study was aimed at setting a standard pharmacognostical and pharmaceutical profile of Asanadi ghanavati (AG. Materials and Methods: Study included preparation of AG following all SOPs using raw drugs, which were previously authenticated. Later, AG was subjected to pharmacognostical, physicochemical and high performance thin-layer chromatography (HPTLC analysis as per standard protocols. Results: The final observations were recorded. Pharmacognostical findings matched with that of individual raw drugs with no major change in the microscopic structure of the raw drugs during preparation of ghanavati. HPTLC gave the fingerprint of the formulation with 12 and eight spots on short and long UV, respectively. Conclusions : The quality of AG tablet can be tested by series of pharmacognostical, Physicochemical screening for the observations of the present study.
Baragi, Umapati C; Baragi, Pramod C; Vyas, Mahesh K; Shukla, Vinay J
Herbal medicines have a long therapeutic history and are still serving many of the health needs of a large population of the world. However, the quality control and quality assurance still remains a challenge because of the high variability of chemical components involved. Herbal drugs, singularly and in combinations, contain numerous compounds in complex matrices in which no single active constituent is responsible for the overall efficacy. This creates a challenge in establishing quality control standards and standardization of finished herbal drugs. Many preparations have been mentioned in Ayurvedic text books for the treatment of Urdhwaga Amlapitta (non-ulcer dyspepsia). Dashanga Kwatha is one such known formulation. In this study, Dashanga Kwatha was converted into tablet form to increase the shelf life, make it easy to dispense, for dose fixation, etc. The Dashanga Kwatha Ghana tablet was subjected to organoleptic analysis, phytochemical analysis, and qualitative analysis to detect the presence of various functional groups, and to high performance thin layer chromatography (HPTLC) examination by optimizing the solvent systems. The investigation revealed the presence of tannins, mucilage, ascorbic acid, alkaloids, saponins, glycosides, flavonoids and carbohydrates mainly. PMID:21897642
Full Text Available Lolimbaraja was the author of Vaidyajivanam popularly known as Lolimbarajeeyam. The author has composed the entire text in a poetic style. This work may be considered as a best piece of Ayurvedic literature consisting of single and simple herbal recipes for common ailments. Though herbal formulations dominated the therapeutics, the author also quoted certain Rasayogas consisting of metals and minerals. In total 37 single drug recipes were documented. The materia medica discussed by Lolimbaraja consists of 153 drugs (130 Herbal drugs, 3 Animal products and 20 Metals and Minerals. The period of Lolimbarajeeyam appears to be belonging to 16th – 17th century. A critical analysis of formulations mentioned in the text clearly indicate that the author consulted many a works of Ayurveda and compiled the most useful recipes which are indicated for the management of the common ailments.
Sunil Kumar; Rashmi Malhotra; Dinesh Kumar
The oldest remedies known to mankind are herbal medicines. India is known worldwide for its Ayurvedic treatment. Euphorbia hirta is often used traditionally for female disorders, respiratory ailments (cough, coryza, bronchitis, and asthma), worm infestations in children, dysentery, jaundice, pimples, gonorrhea, digestive problems, and tumors. It is reported to contain alkanes, triterpenes, phytosterols, tannins, polyphenols, and flavanoids. This review describes the medicinal properties, chem...
Breeher, Laura; Gerr, Fred; Fuortes, Laurence
Introduction Ayurvedic medications consist of herbs that may be intentionally combined with metals, such as lead, mercury, iron, and zinc. Ayurvedic practitioners and their patients believe that the toxic properties of the metals are reduced or eliminated during preparation and processing. Case report A 69 year old Caucasian male retired professional with a prior history of stroke presented for evaluation of new onset depression, fatigue, generalized weakness, constipation, anorexia, and weig...
Saini Vinod; Shah Deepti; Mangal Gopesh; Garg Gunjan; Swarnkar Divya Prakash
Various Ayurvedic calcium compounds, which are among the sudha vargiya dravya, are a rich source of calcium. These calcium compounds have wide range of therapeutic application. In chemical composition these compounds are same hence the present study was aimed to identify the rich percentage of calcium (as CaO) in these Bhasmas. Preparation of Ayurvedic calcium compounds i.e. praval bhasma, shankha bhasma, shukti bhasma, varatika bhasma, godanti bhasma and kukkutandatvak bhasma was done by sub...
Rout, Kedar Kumar; Pradhan, Subhalaxmi; Mishra, Sagar Kumar
A sensitive, simple, rapid, and efficient high-performance thin-layer chromatographic (HPTLC) method has been developed and validated for the analysis of berberine in marketed Ayurvedic formulations containing Berberis aristata DC for regulatory purposes. Chromatography of methanolic extracts of these formulations was performed on silica gel 60 F254 aluminum-backed TLC plates of 0.2 mm layer thickness. The plate was developed up to 66 mm with the ternary-mobile phase butanol-acetic acid-water (8 + 1 + 1, v/v/v) at 33 +/- 5 degrees C with 5 min of tank saturation. The marker, berberine, was quantified at its maximum absorbance of 350 nm. The limit of detection and limit of quantitation values were found to be 5 and 10 ng/spot. The linear regression analysis data for the calibration plot showed a good linear relationship with correlation coefficient = 0.9994 in the concentration range of 10 to 50 ng/spot for berberine with respect to peak area. The instrumental precision was found to be 0.49% coefficient of variation (CV), and repeatability of the method was 0.73% CV. Recovery values from 98.27 to 99.11% indicate excellent accuracy of the method. The developed HPTLC method is very accurate, precise, and cost-effective, and it has been successfully applied to the assay of marketed formulations containing B. aristata for determination of berberine. PMID:18980133
Full Text Available Respiration is the evident feature of life which is carried out by Prana vayu. This sole sign of life is affected in this disease Tamaka Shwasa, causing an impediment to the Respiratory function. Shwasa word indicates both physiological and pathological state of respiration. Ayurvedic texts have mentioned Tamaka Shwasa under the various types of Shwasa roga. Disease Tamaka Shwasa can be correlated with the disease Bronchial Asthma on the basis of its features & etiopathogenesis. Tamaka Shwasa is considered as Yapya (palliable because this type of Shwasa roga is not only difficult to treat but also has a repetitive nature. Bronchial Asthma calls the attention of Medical world due to significant burden in terms of healthcare costs as well as lost productivity and reduced participation in family life. The Science of Life – Ayurveda is the best way to effectively & safely manage the condition without inducing any drug dependency where various Shodhana procedures and use of internal medication not only detoxifies the body but also provides nutrition & increases the elasticity of lung tissue & develops natural immunity of the body thus decreasing episodic recurrence of the disease and providing long term relief to the patient.
Baragi Umapati C.
Full Text Available This present study deals with pharmacognostic and analytical study of Dashanga Kwatha (A known Ayurvedic formulation used in Non Ulcer Dyspepsia. Here attempt was made to find out the authenticity of the drugs used in the formulation. This forms the first step in the standardization of a formulation. Herbal drugs, singularly or in combinations, contain numerous compounds in complex matrices in which no single active constituent is responsible for the overall efficacy. The pharmacognostic investigations were carried out in terms of organoleptic, microscopic, macroscopic examinations and the analytical study was carried in terms of physicochemical, phytochemical analysis and HPTLC examination by optimizing the solvent systems. Microbial load of dried powder material was determined to avoid the contamination and for safety of crude drug. The present work will provide referential information for the correct identification and standardization of the crude drug and will ensure the use of only genuine and uniform material in preparation of Dashanga Kwatha in future. These findings will be useful in establishing quality control standards and standardization of Dashanga Kwatha in future.
Full Text Available A simple and reproducible UV- spectrophotometric method for the quantitative determination of piperine in Sitopaladi churna (STPLC were developed and validated in the present work. The parameters linearity, precision , accuracy, and standard error were studies according to indian herbal pharmacopiea. In this present study a new, simple, rapid, sensitive, precise and economic spectrophotometric method in ultraviolet region has been developed for the determination of piperine in market and laboratory herbal formulation of Sitopaladi churna. which were procured and purchased respectively from the local market and they were evaluated as per Indian herbal Pharmacopoeia and WHO guidelines. The concentration of piperine present in raw material of PSC was found to be 1.45±0.014 w/w in piper longum fruits. Piperine has the maximum wavelength at 342.5 nm and hence the UV spectrophotometric method was performed at 342.5 nm. The samples were prepared in methanol and methos obeys Beers law in concentration ranges employed for evaluation. The content of piperine in ayurvedic formulation was determined. The result of analysis have been validated statistically and recovery studies confirmed the accuracy of the proposed method. Hence the proposed method can be used for the reliable quantification of Piperine in crude drug and its herbal formulation.
Ashok Kumar; A C Rana
Myrica nagi belongs to myricaceae family. It is commonly known as Bay berry (English) and Kathphal (Hindi). Myrica nagi has a long history of usage in traditional medicine against various ailments. In Ayurvedic and other traditional medicinal practices the plant has been used against diseases like, fever, Cardiac debility, typhoid, diarrhoea, dysentery. Phytochemicals like glycosides, saponins tannins, flavonoids, triterpenes and sterols have been isolated. Important pharmacological activitie...
Munish Garg* and Jaspreet Singh
Full Text Available Churna preparations are an important and widely used form of Ayurvedic herbal formulations in India. These are prepared by mixing powdered form of single or mixture of several crude drugs meant to be dispensed as such. Since the quality of raw material plays an important role in the overall quality of a herbal formulation due to common practice of collecting and processing medicinal plants from different geographical sources and the fact presence of certain trace elements and heavy metals have a great significance in this matter, the present study is based on the screening of 19 popular herbal Churna preparations sold in the Indian market for the quantitative analysis of essential trace and toxic heavy metals by atomic absorption spectrometry. Heavy metals like Pb, Cd and trace metals like Ca, Mg, Al, Cu, Zn were determined using flame atomic absorption spectrometer (FAAS and heavy metals such as As and Hg were determined by hydride generation technique (cold vapour atomic absorption spectrometery. The results reveal that among the trace (micronutrients metals Ca and Mg were found in highest amount. Sixteen samples for Hg content and eight for Pb content were exceeding the WHO permissible limits. Arsenic was found below the permissible limit while Cd was above the permissible limit in all the tested samples. In conclusion, the quality of herbal Churna preparations sold in India market is questionable and need to be regulated efficiently before launching in to the market. Besides, the present paper provides a simple, convenient and reliable AAS method for the quantitative analysis of trace and heavy metals in herbal products which can be utilized for industrial purpose.
Santosh S. Kulkarni
Full Text Available The Metals and Minerals are heavy, nonabsorbable and toxic substances. Metals are used as medicines in Ayurveda since from Samhita period in the fine powder form named as ‘Ayaskriti’1. Latter with the development of ‘Marana’ technique (7th Cent AD the Metals and Minerals are converted in to very very fine and absorbable, therapeutically most effective and least or Nontoxic form of Medicines known as ‘Bhasma’2. According to Ayurvedic concept the change in the qualities is due to ‘Samskara’ done through Shodhana, Bhavana, Putapaka procedures by which particle size of Metals and Minerals are reduced to finer and finer form of Bhasma.The Bhasma particles when analyzed microscopically through SEM and TEM fall under the range of Nanoparticles of contemporary science.Nano technology based on Nano science is the technology of 21st century due to its wide range of application in Medicines, Automobiles, Computers, Clothes, communications, cosmetics, sports goods etc. In nano science the materials of very small dimension in the range of 1 to 100nm are studied. When atleast one of the dimensions of any type of materials is reduced below 100nm it’s mechanical, thermal, optical, magnetic and other properties change at some size characteristic of that material. In this paper I have explained basic principle of change of properties of substances at their Nano level. The Mukta shukti bhasma & Swarna Bhasma when analysed through SEM they are in Nano particle size. Thus bhasma can be considered as Nano Medicine of Ayurveda. It is an attempt to understand and apply basics of Nanotechnology in Ayurvedic Pharmaceutics.
Full Text Available Medicinal plants are part and parcel of human society to combat diseases, from the dawn of civilization. There exists a plethora of knowledge, information and benefits of herbal drugs in our ancient literature of Ayurvedic (Traditional Indian Medicine, Siddha, Unani and Chinese medicine. According to the World Health Organization, 2003 about 80 % of the population of developing countries being unable to afford pharmaceutical drugs rely on traditional medicines, mainly plant based, to sustain their primary health care needs. Herbal medicines are in great demand in the developed as well as developing countries for primary healthcare because of their wide biological and medicinal activities, higher safety margins and lesser costs. In this review we have enlisted the updated anthelmintic medicinal plants which are used as good alternatives for the traditional allopathic anthelmintic agents.
Srivastava, Sharad; Rawat, A K S
Berberis aristata known as "Daruharidra" in Ayurveda is a versatile medicinal plant used singly or in combination with other medicinal plants for treating a variety of ailments like jaundice, enlargement of spleen, leprosy, rheumatism, fever, morning/evening sickness, snakebite, and so forth. A major bioactive marker of this genus is an alkaloid berberine, which is known for its activity against cholera, acute diarrhea, amoebiasis, and latent malaria and for the treatment of oriental sore caused by Leishmania tropica. Although the roots of B. aristata are considered as the official drug (Ayurvedic Pharmacopoeia of India), the study revealed that different species of Berberis, namely. B. asiatica, B. chitria, and B. lycium are also used under the name of Daruharidra in different parts of the country. Detailed physicochemical and phytochemical studies of subjects like total ash, acid insoluble ash, tannins, and total alkaloids were calculated from the shade dried powdered material according to the recommended procedures. Further, heavy metal studies and quantitative estimation of berberine through HPTLC have also been performed as per ICH guidelines. A detailed study of four Berberis species, namely B. aristata, B. asiatica, B. chitria, and B. lycium, which are implicated as Daruharidra and collected from wild and ten commercial samples procured from various important drug markets in India has been carried out, which may be useful to pharmaceutical industries for the authentication of the commercial samples and exploring the possibilities of using other species as a substitute of B. aristata. PMID:23431340
Full Text Available Berberis aristata known as “Daruharidra” in Ayurveda is a versatile medicinal plant used singly or in combination with other medicinal plants for treating a variety of ailments like jaundice, enlargement of spleen, leprosy, rheumatism, fever, morning/evening sickness, snakebite, and so forth. A major bioactive marker of this genus is an alkaloid berberine, which is known for its activity against cholera, acute diarrhea, amoebiasis, and latent malaria and for the treatment of oriental sore caused by Leishmania tropica. Although the roots of B. aristata are considered as the official drug (Ayurvedic Pharmacopoeia of India, the study revealed that different species of Berberis, namely. B. asiatica, B. chitria, and B. lycium are also used under the name of Daruharidra in different parts of the country. Detailed physicochemical and phytochemical studies of subjects like total ash, acid insoluble ash, tannins, and total alkaloids were calculated from the shade dried powdered material according to the recommended procedures. Further, heavy metal studies and quantitative estimation of berberine through HPTLC have also been performed as per ICH guidelines. A detailed study of four Berberis species, namely B. aristata, B. asiatica, B. chitria, and B. lycium, which are implicated as Daruharidra and collected from wild and ten commercial samples procured from various important drug markets in India has been carried out, which may be useful to pharmaceutical industries for the authentication of the commercial samples and exploring the possibilities of using other species as a substitute of B. aristata.
Full Text Available According to Sushruta, no plant in this world is useless. A large number of crude drugs used in Ayurvedic system employ plants of family Fabaceae. The family Fabaceae popularly known as legumes, is the third largest order of seed-plants containing about 600 genera with 12,000 speices. All the three subfamilies of Fabaceae have been given the status of family and hence they will be treated here as distinct families. Details of medicinal plants of these families and their uses are presented here.
Full Text Available Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of drugs. World health organization (WHO in 1999 has given a detail protocol for the standardization of herbal drugs comprising of a single content but very little literature is available for the standardization of polyherbal formulations. Chitrakadi Vati is official in ayurvedic formulary of India and it is prescribed for the treatment of irritable bowel syndrome, rheumatoid arthritis and loss of appetite. In the present work, attempt has been made to develop a chromatographic method for standardization of Chitrakadi Vati. All raw materials used were standardized by macroscopic, microscopic and physico-chemical parameters. Piperine in Piper nigrum and Piper longum; Plumbagin in Plumbago zeylanica are active components in the formulation and can be considered as marker compounds. A simple, rapid, precise, accurate and reproducible High Performance Thin Layer Chromatography (HPTLC densitometric method was developed. The separation was performed on TLC aluminium plates precoated with silica gel 60 F254, good separation was achieved in the mobile phase of toluene: ethyl acetate: formic acid (7.5:2.5:0.5 v/v/v and densitometry determination of piperine (0.39 ± 0.02 and plumbagin (0.70 ± 0.02 was carried out at single wavelength scanning at 280 nm. The developed method has been validated as per ICH (International conference on harmonization guidelines. The developed and validated HPTLC method was applied for standardization of Chitrakadi Vati by detection and quantification of markers piperine and plumbagin simultaneously from in-house and marketed formulations.
Kumar, A; Singh, G; Kumar, N
This work reviews the contents of an Ayurvedic treatise "Sri Ranbira Cikitsa Sudha Sāra" authored by Kaviraj Neel Kanth in the year 1931 of Vikrami, in 'Takari' script, the official script during the reign of his highness Maharaja Ranbir Singh of Jammu and Kashmir. A copy of the book is presently available with Raghunath Sanskrit Library, Jammu in torn condition. This is a humble effort by the authors for the exploration of hidden and old Ayurvedic literature of Jammu and Kashmir. PMID:12841189
Radhika K Varma; Manjusha R; CR Harisha; Shukla VJ
In Ayurvedic classical texts administration of potent psycho-physical rejuvenator formulations comes under Rasayana chikitsa which frees one of diseases, improves quality of life and delays senile degenerative changes. Eleven among the most commonly used anti-oxidant, adaptogenic potent, well established rejuvenator herbs viz., Hareetaki (Terminalia chebula Retz), Vibheetaki (Terminalia bellerica Roxb) Amalaki (Emblica officinalis Linn), Guduchi (Tinospora cordifolia Miers), Gokshura (Tribu...
Nair, K.V.; Yoganarasimhan, S.N.; Murthy, K.R. Kesava; Shantha, T. R.
Ayurveda is not exploited to the maximum extent in the islands. In order to provide a basic data for establishing Ayurvedic and allied pharmaceutical based industries, information of on fortyfour drugs available in the islands are provided in this first paper of the series
Nair, K.V.; Yoganarasimhan, S.N.; Murthy, K.R. Kesava; Shantha, T.R.
Ayurveda is not exploited to the maximum extent in the islands. In order to provide a basic data for establishing Ayurvedic and allied pharmaceutical based industries, information of on fortyfour drugs available in the islands are provided in this first paper of the series PMID:22557452
Full Text Available Foods which are mentioned in Ayurvedic textbooks for the management of obesity are aimed to pacify Kapha Dosha and Medodhatu, cause downward movement of Vata, are rich in dietary fiber and have low glycemic index. The aim of the study was to evaluate the efficacy of diet which is mentioned in Ayurvedic textbook in the management of obesity. 50 subjects with features of obesity as per classics and body mass index (BMI more than 25 kg/m2 were included into study, out of which 40 subjects completed the study. In Ayurveda diet group, diet which contains horsegram, barley, greengram and Kokum fruit was advised. In standard diet group, the standard diet menu was followed according to ICMR guidelines. Both groups were given 1100 kcal diet for eight days. With diet control, both groups underwent brisk walking 20 minutes two times, jogging 20 minutes, Yogasana 40 minutes, cycling 15 minutes, Udvartana (powder massage 20 minutes and Baspasweda (sudation 10 minutes. Ayurvedic diet plan with physical exercise was found to be more effective in reducing all the anthropometric parameters. There was significant reduction in triglyceride (p value 0.000 and VLDL level (p value 0.013 in Ayurvedic diet group. Ayurveda group showed better relief in most of the subjective parameters among which, the effect on pacifying hunger was statistically significant (p value 0.039.
Chopra, Arvind; Saluja, Manjit; Tillu, Girish; Venugopalan, Anuradha; Sarmukaddam, Sanjeev; Raut, Ashwini Kumar; Bichile, Lata; Narsimulu, Gumdal; Handa, Rohini; Patwardhan, Bhushan
The multidisciplinary "New Millennium Indian Technology Leadership Initiative" Arthritis Project was undertaken to validate Ayurvedic medicines. Herbal formulations in popular use were selected by expert consensus and standardized using modern tools. Our clinical strategy evolved from simple exploratory evaluations to better powered statistically designed drug trials. The results of the first drug trial are presented here. Five oral formulations (coded A, B, C, D and E), with a common base of Zingiber officinale and Tinospora cordifolia with a maximum of four plant extracts, were evaluated; with placebo and glucosamine as controls. 245 patients suffering from symptomatic OA knees were randomized into seven arms (35 patients per arm) of a double blind, parallel efficacy, multicentric trial of sixteen weeks duration. The groups matched well at baseline. There were no differences for patient withdrawals (17.5%) or adverse events (AE) of mild nature. Intention-to-treat efficacy analysis, demonstrated no significant differences (P < .05) for pain (weight bearing) and WOMAC questionnaire (knee function); placebo response was high. Based on better pain relief, significant (P < .05) least analgesic consumption and improved knee status, "C" formulation was selected for further development. Controlled exploratory drug trials with multiple treatment arms may be used to economically evaluate several candidate standardized formulations. PMID:20981160
The importance of various herbal ingredients and plant derivatives in immunomodulation is a subject for scientific investigations currently worldwide. The mystery of Moringa oleifera as a vegetable source for immunomodulation in human and its capacity to impart protection against diseases by building host resistance has made it an important and economical nutritional supplement majorly in developing countries. The coconut fruit obtained from the coconut palm has numerous medical and commercia...
Wele, Asmita A.; Pendse, Nikhil U.; Takle, Shrikant P.; Burase, Raghunath V.; Patil, Sanjay V.; Bhalerao, Supriya; Harsulkar, Abhay M.
Introduction: Vasarishta built upon Mritasanjeevani Sura (MS) is a polyherbal hydro-alcoholic anti-asthmatic formulation which is administered in a dose of 1 ml instead of standard dose 40 ml, generally advocated for any “Asava–Arishta” in Ayurveda. Aim: The present study was aimed at finding out rationale for the peculiar distillation process to manufacture MS followed by Sthapana process to make Vasarishta. It was further aimed to find out difference in Vasarishta samples manufactured by purely fermentation process and the peculiar method mentioned above. Materials and Methods: Three batches of MS and subsequently three batches of Vasarishta were prepared. Basic standardization and development of standard operating procedure for the same were achieved by doing pH, percentage of alcohol and total reducing sugar, specific gravity on both MS and Vasarishta, during and after completion of process. Finally, MS and Vasarishta (built upon MS) made in laboratory were compared with marketed samples of MS and Vasarishta using gas chromatography. Results: The types of alcohols and volatile acids in MS and Vasarishta, prepared in laboratory, are similar but the proportions differ, which is taken as an indicator of process standardization. Values of furfural, ethyl acetate, and 1-butanol in lab samples are within permissible limits as against the values of the market samples. Conclusions: The textual process for the production of Vasarishta proved to produce organoleptically acceptable product which is virtually free of toxic compounds such as furfural.
Kumar, Dinesh; Rawat, Atul; Dubey, Durgesh; Kumar, Umesh; Keshari, Amit K.; Saha, Sudipta; Guleria, Anupam
Traditional Indian (Ayurvedic) and Chinese herbal medicines have been used in the treatment of a variety of diseases for thousands of years because of their natural origin and lesser side effects. However, the safety and efficacy data (including dose and quality parameters) on most of these traditional medicines are far from sufficient to meet the criteria needed to support their world-wide therapeutic use. Also, the mechanistic understanding of most of these herbal medicines is still lacking...
Several arguments have been forwarded for the stagnation of Ayurveda, and most of these focus on the discrimination that Ayurveda faces under Mughal and then under British rule. Even for Ancient India, the halcyon portrait of Ayurveda synergetically related with religion and politics during the period, as has been portrayed in many books of history and in countless lores, is false. This paper then deals with the interaction between the State and Ayurvedic medicine in ancient India.
Full Text Available Snakebite is an important cause of morbidity and mortality and is one of the major health problems in India. About 30000 to 40,000 persons die each year from venomous snake bite. Russell’s viper or daboia (Viper russelli appears to be the commonest cause of fatal snakebite in Southern India, Pakistan, Bangladesh, Sri Lanka, Burma and Thailand. Intravenous administration of anti-snake venom neutralizes the systemic actions, however, antiserum does not provide enough protection against venom induced hemorrhage, necrosis, nephrotoxicity and often develops hypersensitivity reactions. India has a rich tradition of the usage of medicinal plants. Many Indian medicinal plants are mentioned in Ayurvedic literature to treat snakebite victims and are used by many ayurvedic practioners as well as in rural areas by traditioners. So much research work has been conducted for anti-snake venom activity of herbal medicine as alternative for Anti Snake Venom. This article presents a review of such herbal drugs which are effectively neutralize the snake venom like vitex nigundo, Emblica officinalis, Hemidesmus indicus etc which were assayed in research laboratories. It is considered as a valuable source of natural products for development of medicines against venomous snake bite.
Ayurveda, a rational system of medicine have gained global acceptance on virtue of its fundamental doctrine of holistic approach. In India 3.8% of the population are older than 65 years of age. According to an estimate the likely number of elderly people in India by 2016 will be around 113 million. Maintaining the vitality of youth and preserving quality of life has long been a quest of civilized man. Ayurveda Rasayana tantra describes technique providing multidimensional solutions to ageing,...
Full Text Available The oldest remedies known to mankind are herbal medicines. India is known worldwide for its Ayurvedic treatment. Euphorbia hirta is often used traditionally for female disorders, respiratory ailments (cough, coryza, bronchitis, and asthma, worm infestations in children, dysentery, jaundice, pimples, gonorrhea, digestive problems, and tumors. It is reported to contain alkanes, triterpenes, phytosterols, tannins, polyphenols, and flavanoids. This review describes the medicinal properties, chemical constituents, and other important aspects of Euphorbia hirta.
Timbadiya, Manoj J.; Nishteswar, K.; Acharya, Rabinarayan; Nariya, Mukesh B.
Introduction: In Ayurvedic classics, the symptom fever is considered as a separate disease called Jwara. Acharya Sushruta has mentioned Amalakyadi Gana for treatment of all types of Jwara, which contains four drugs namely Amalaki (Emblica officinalis Gaertn.), Haritaki (Terminalia chebula Retz.), Pippali (Piper longum L.), and Chitraka (Plumbago zeylenica L.). Aims: To evaluate the antipyretic and analgesic activity of Amalakyadi Gana in experimental animals. Materials and Methods: Decoction ...
Sarvesh Kumar Singh
Full Text Available Spinal cord injury (SCI is associated with consequences such as full loss of spinal movements, incontinence of bladder functions, bed sores, etc. There is no satisfactory treatment available in biomedicine with only limited treatments only for enhancement of spinal cord function. These treatments have many limitations. Ayurvedic drugs and Pancakarma procedures have been in use to treat such conditions since a long time. We present a case of SCI with lesion at C4 level which was treated for 2 months with an Ayurvedic combined intervention. The combined treatment plan involved Ayurvedic oral medications (Brhadvātacintāmaṇi rasa - 125 mg, Ardhanāgavātāri rasa - 125 mg, Daśamūla kvātha - 40 ml, Aśvagandhācūrṇa [powder of Withania somnifera DUNAL] - 3 g, Amṛtā [Tinospora cordifolia WILLD] - 500 mg, Muktāśukti piṣṭi - 500 mg and Trayodaśāṅga guggulu - 500 mg twice daily. Combined procedures involved such as śāliṣaṣṭika piṇḍasvedana (sudation with medicated cooked bolus of rice every day for 2 months and Mātrā basti (enema for first 15 days with Aśvagandhā oil. From 16 th day, Mustādi yāpana basti (MYB, enema with medicated milk was given for 16 days. After an interval of 7 days, MYB was further repeated for next 16 days. Substantial clinical improvement was reported after 2 months of the Ayurvedic treatment in existing neurological deficits and in quality of life.
Singh, Sarvesh Kumar; Rajoria, Kshipra
Spinal cord injury (SCI) is associated with consequences such as full loss of spinal movements, incontinence of bladder functions, bed sores, etc. There is no satisfactory treatment available in biomedicine with only limited treatments only for enhancement of spinal cord function. These treatments have many limitations. Ayurvedic drugs and Pancakarma procedures have been in use to treat such conditions since a long time. We present a case of SCI with lesion at C4 level which was treated for 2 months with an Ayurvedic combined intervention. The combined treatment plan involved Ayurvedic oral medications (Brhadvātacintāmaṇi rasa - 125 mg, Ardhanāgavātāri rasa - 125 mg, Daśamūla kvātha - 40 ml, Aśvagandhācūrṇa [powder of Withania somnifera DUNAL] - 3 g, Amṛtā [Tinospora cordifolia WILLD] - 500 mg, Muktāśukti piṣṭi - 500 mg and Trayodaśāṅga guggulu - 500 mg) twice daily. Combined procedures involved such as śāliṣaṣṭika piṇḍasvedana (sudation with medicated cooked bolus of rice) every day for 2 months and Mātrā basti (enema) for first 15 days with Aśvagandhā oil. From 16(th) day, Mustādi yāpana basti (MYB, enema with medicated milk) was given for 16 days. After an interval of 7 days, MYB was further repeated for next 16 days. Substantial clinical improvement was reported after 2 months of the Ayurvedic treatment in existing neurological deficits and in quality of life. PMID:26283809
Kinjal Shah; Priyanka Burange; Sunita Singh
The incessant and vital need to discover new antimicrobial compounds with diverse chemical structures and novel mode of action is stimulated by the increasing failure of chemotherapeutics and expanded antibiotic resistance exhibited by pathogenic agents. In the present research work, antimicrobial activity of few plant extracts and ayurvedic samples were screened against bacteria. Phytochemical analysis of active plant extracts showed the presence of triterpenes, glycosides and flavonoids. Bo...
Nakanekar, Amit; Bhople, Sunanda; Gulhane, Harshad; Rathod, Suraj; Gulhane, Jayant; Bonde, Pravin
Guillain-Barre syndrome is an acute, frequently severe and fulminant polyradiculopathy that is autoimmune in nature. Guillain Barre syndrome is a rare disorder that causes immune systems to attack peripheral nervous system (PNS). A 46 year old male patient, presenting with sudden onset, complete paralysis of all four limbs (quadriplegia), unable to walk, stand, sit, difficulty in deglutition (dysphagia) and dysarthia, was having foley's catheter and Ryle's Tube brought by relative to Out Door Patient Department (OPD) of Government Ayurvedic Hospital, Nagpur; He was provisionally diagnosed as subacute sensory motor paraplegia. Previously patient admitted and treated in Government Medical College (GMC) Nagpur but did not show any sign of improvement so patient was admitted and treated with Ayurvedic treatment for about 50 days. As per Ayurvedic classics, this condition can be correlated with sarvāṅ gagatavātavyādhi (~vāta disorder affecting all parts of the body), which is apatarpaṇa in nature (~diseases with deprived nourishment of body tissue) preceded by jvara (~(H/O fever before onset of GBS). Hence, the principle of treatment is santarpaṇa cikitsā (~nourishing treatment). Santarpaṇa (~nourishing treatment) includes bahyopakramas (~nourishing external treatment modalities), such as abhyaṅga (~oleation therapy) and ṣaṣṭikaśālipiṇḍasveda (~sudation using of hot and processed ṣaṣṭika rice), karmabasti (~medicated enema) śirodhārā (gentle pouring of medicated liquid over forehead) and jvaraghna cikitsā (~treatment of fever) using various Ayurvedic herbomineral compounds. Remarkable results were observed in the form of improvement in the muscle power from zero to five of all four limbs with improvement in speech. There was no difficulty post treatment in deglutition, sitting, standing and walking; and now patient has near to normal movements. PMID:26600668
Hetal Amin; Rohit Sharma
Introduction: Ayurveda is known for philosophical basis, and its approach to psychological ailments is quite different from conventional system of management. Satvavajaya Chikitsa (Ayurvedic psychotherapy) is a nonpharmacological approach aimed at control of mind and restraining it from unwholesome Artha (objects) or stressors. Withdrawal of the mind from unwholesome objects is known as Sattvavajaya Chikitsa or it is a treatment by Self Control. Charaka defines it as a mind controlling therap...
Rahul K Dumbre; Manisha B Kamble; Patil, Vijay R.
Background: Ayurveda recommends several plants and plant preparation for conditions of urogenital disorders as per its principles. Objectives: Ayurvedic plants Tamala (Cinnamomum tamala); Daruhalad (Berberis aristata); Ativish (Aconitum heterophyllum) were studied for mechanisms of prostatic hyperplasia induced in rats. Materials and Methods: Prostatic enlargement was induced in castrated rats by testosterone injection s.c. for 21 days and simultaneously plants were dosed orally daily. On day...
Kajaria Divya; Kajaria Ankit; Tripathi J.S.; Tiwari S.K
Asthma is one of the most prevalent chronic inflammatory lung diseases among children and adults. A lot of work had been done in various field (including both modern and Ayurvedic) on anti-asthmatic drugs to evaluate their action on lungs. The parameters chosen for assessing the properties of drug is mainly based on clinical improvement and improvement in pulmonary function test. These all method employed so far are indirect method for assessment of action of drug on lungs as change in pulmon...
Hullatti, K. K.; Sharada, M. S.
Standardization of herbal drugs based on their chemical and biological activity profile is an important prerequisite for acquiring the herbal market. The main problem encountered in standardization of Ayurvedic drugs is proper identification of the source plant. The present study was aimed to establish identification characters, quality control parameters, chemical and biological parameters for roots of three plants Cissampelos pareira, Cyclea peltata and Stephania japonica (Fam. Menispermace...
Ayurvedic herbals, Indian honeys, and dry tea leaves were found to contain significant level of microbial load posing serious health concern upon consumption. Hence, these commodities were radiation processed using gamma rays to achieve microbial decontamination, which was achieved at 5, 10, and 15 kGy dose for tea, herbals, and honeys, respectively. Physical, biochemical, antioxidant, antimicrobial, and organoleptic attributes of these samples were not affected by radiation processing. (author)
Prasad, Goli Penchala; Babu, G.; Swamy, G. K.
Diabetes Mellitus (Madhumeha) is a well-known clinical syndrome since antiquity. First time the role of Diet in the prevention, etiology and treatment of Diabetes was mentioned in Ayurveda under the heading of Prameha and Madumeha. Caraka Samhita, Susruta Samhita and other Ayurvedic classics have appropriate descriptions on the role of diet, habits and life style in Prameha and Madhumeha, which is akin to Diabetes. Recent modern (contemporary) Researches and statistics support these descripti...
Subrata De et al
Panchagavya, a classical Ayurvedic preparation, was evaluated for its antioxidant potential by HPTLC-DPPH bioautography method as well as assays for Ferric reducing antioxidant power (FRAP), DPPH – free radical scavenging activity (DPPH) and Superoxide radical scavenging activity. In addition total phenolic content was also estimated which was in fairly good amount. HPTLC-DPPH bioautography study revealed the presence of several antioxidant compounds in Panchagavya. In all the assays performe...
Full Text Available Shankhapushpi (Convolvulus pluricaulis Choisy, CP is an extremely versatile plant, commonly prescribed as nootropic (medhya, rejuvenator, nervine tonic in epilepsy, insanity and possesses wide range of therapeutic attributes. Since it is an essential ingredient of myriad popular Ayurvedic monoherbal or polyherbal preparations, it is commercially quite exploitable. Although CP exhibits a wide range of therapeutic attributes, only scattered information exploring the curative potential of CP is available, and there is a need to assemble it. Therefore, to revalidate the Ayurvedic therapeutic claims of Shankhapushpi in light of contemporary experimental and clinical studies, this study was carried out. Information was extracted from various Ayurvedic literature viz. Brihattrayi (Charaka Samhita, Sushruta Samhita and Ashtanga Hridaya and Nighantu (lexicon. Online studies available on Convolvulus pluricaulis Choisy published in Pubmed, Scopemed, Pubmed Central Databases, Dhara online database and other allied databases were also rationally reviewed and documented in the present review. The current work appears to be the first of its kind and can be considered a reference standard for future studies.
K.V. Ram Subba Rao; Naidu M.L.
This article describes the detailed preparation of Lohabhasma (iron oxide in cinerated iron) and Trushanadi Loha. The metal concentrations present in this compound evaluated by using wavelength dispersive X-ray flourosence (WD-XRF) Spectometry. A total of 19 elements, Na, Mg, Al, Si, P, S, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, As, Cl, Sr and bromine from medicine were characterized. Out of 19 elements listed which are considered to be essential to the life system. 9 are macro-nutrients (Na,,Mg,...
Sunil Dutt Shukla
Full Text Available Oxidative damage caused by free radicals plays an important role in the causation and progression of many diseases, including aging. Free radical damage is countered by many mechanisms, including both active antioxidant enzymatic activity in our body and passive antioxidants. Antioxidant response of our body can accommodate increased oxidative damage in diseased states to a level but beyond that level, additional antioxidants are required to combat the increased stress. Apart from the regular dietary sources of antioxidants, many traditional herbal medicines demonstrate a potential to boost antioxidant activity. Rasayana chikitsa that deals with rejuvenation and revitalization is a branch of the Indian traditional medical system of Ayurveda. We review some select herbs described in Rasayana chikitsa that have been assessed by modern means for stimulating intrinsic antioxidant responses in humans. A critical evaluation of Rasayana chikitsa will likely provide urgently needed, actual stimulants of our physiological antioxidant responses and not just more passive antioxidants to an already large catalogue.
Full Text Available Ayurveda, a rational system of medicine have gained global acceptance on virtue of its fundamental doctrine of holistic approach. In India 3.8% of the population are older than 65 years of age. According to an estimate the likely number of elderly people in India by 2016 will be around 113 million. Maintaining the vitality of youth and preserving quality of life has long been a quest of civilized man. Ayurveda Rasayana tantra describes technique providing multidimensional solutions to ageing, premature ageing and their complications. There is a sharp increase in variation in function with ageing. An organ function may appear to undergo a moderate decline with age on a population basis. Scientific studies in Ayurveda have proven the preventive efficacy for ageing (Vriddhaawastha and its conditions just because of Rasayana therapy and with the help of dietary prevention.
Rizzo-Sierra, Carlos V
A recent methodological approach for human classification, diagnosis, and therapeutics through the combination of current Western constitutional psychology somatotypes and traditional Indian medicine (prakriti) body types and mind (manas) is herein presented. The striking similarities between psychologic somatotypes and Indian medicine body types permits proposal of a finite genopsycho-somatotyping of humans. Genopsycho-somatotyping of humans consists of a set of common physiologic, physical, and psychologic attributes related to a common basic birth constitution that remains somewhat permanent during human lifetime, since it is proposed that this birth constitution is programmed in the person's DNA (genes). This mainly provides a tool for classifying the human population based on broad and finite phenotype clusters across different ethnicity, languages, geographical location, or self-reported ancestry. In spite of any social or environmental traumatic event, I propose for males that every basic constitution has an associated identification organ, a measured property or marker, a soma, and some psyche general tendencies suggesting specific behavior or recurrent conduct. Three (3) basic extreme genopsycho-somatotypes or birth constitutions are enunciated: mesomorphic or andrus (Pitta), endomorphic or thymus (Khapa), and ectomorphic or thyrus (Vata). The method further predicts that male andrus constitution across races shares similarities in androgen (An) nuclear receptor behavior, whereas thymus constitutions are mainly regulated by T-cells (Tc) nuclear receptor behavior. Moreover, it suggests that thyrus constitutions share similarities in thyroxine (Th) nuclear receptor behavior. These proposed nuclear receptors are expected to regulate the expression of specific genes, thereby controlling the embryonic development, adult homeostasis, and metabolism of the human organism in a very profound way. The method finally predicts small differences in measured property
Biswas, Tuhin Kanti; Mukherjee, Biswapati
Research on wound healing drugs is a developing area in modern biomedical sciences. Scientists who are trying to develop newer drugs from natural resources are looking toward the Ayurveda, the Indian traditional system of medicine. Several drugs of plant, mineral, and animal origin are described in the Ayurveda for their wound healing properties under the term Vranaropaka. Most of these drugs are derived from plant origin. Some of these plants have been screened scientifically for the evaluation of their wound healing activity in different pharmacological models and patients, but the potential of most remains unexplored. In a few cases, active chemical constituents were identified. Some Ayurvedic medicinal plants, namely, Ficus bengalensis, Cynodon dactylon, Symplocos racemosa, Rubia cordifolia, Pterocarpus santalinus, Ficus racemosa, Glycyrrhiza glabra, Berberis aristata, Curcuma longa, Centella asiatica, Euphorbia nerifolia, and Aloe vera, were found to be effective in experimental models. This paper presents a limited review of plants used in Ayurvedic medicine. PMID:15866825
Allergic Contact Dermatitis (type IV hypersensitivity and type I hypersensitivity following aromatherapy with ayurvedic oils (Dhanwantharam thailam, Eladi coconut oil presenting as generalized erythema and pruritus with flexural eczema
Full Text Available Herbal and Ayurvedic medications, believed to be "mild" and "natural" are usually sought as the first line of treatment before resorting to "stronger" allopathic medication. There are very few reports of adverse reactions to either topical and/or systemic Ayurvedic medications. Massage aromatherapy with ayurvedic oils plays an important role in alleviation of pain, but may cause allergic contact dermatitis. This is the second case report of allergic contact dermatitis to ayurvedic oil.
Allergic Contact Dermatitis (type IV hypersensitivity) and type I hypersensitivity following aromatherapy with ayurvedic oils (Dhanwantharam thailam, Eladi coconut oil) presenting as generalized erythema and pruritus with flexural eczema
Herbal and Ayurvedic medications, believed to be "mild" and "natural" are usually sought as the first line of treatment before resorting to "stronger" allopathic medication. There are very few reports of adverse reactions to either topical and/or systemic Ayurvedic medications. Massage aromatherapy with ayurvedic oils plays an important role in alleviation of pain, but may cause allergic contact dermatitis. This is the second case report of allergic contact dermatitis to ayurvedic oil.
Allergic Contact Dermatitis (Type IV Hypersensitivity) and Type I Hypersensitivity Following Aromatherapy with Ayurvedic Oils (Dhanwantharam Thailam, Eladi Coconut Oil) Presenting as Generalized Erythema and Pruritus with Flexural Eczema.
Herbal and Ayurvedic medications, believed to be "mild" and "natural" are usually sought as the first line of treatment before resorting to "stronger" allopathic medication. There are very few reports of adverse reactions to either topical and/or systemic Ayurvedic medications. Massage aromatherapy with ayurvedic oils plays an important role in alleviation of pain, but may cause allergic contact dermatitis. This is the second case report of allergic contact dermatitis to ayurvedic oil. PMID:24891661
K.V. Ram Subba Rao
Full Text Available This article describes the detailed preparation of Lohabhasma (iron oxide in cinerated iron and Trushanadi Loha. The metal concentrations present in this compound evaluated by using wavelength dispersive X-ray flourosence (WD-XRF Spectometry. A total of 19 elements, Na, Mg, Al, Si, P, S, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, As, Cl, Sr and bromine from medicine were characterized. Out of 19 elements listed which are considered to be essential to the life system. 9 are macro-nutrients (Na,,Mg,Al,Si,P,S,K,Ca,Ti and 5 are defined as micro-nutrients (Mn, Fe, Cu, Zn, Ni. The method was measured by Fast-Vac 34 .The sample was examined by inductively coupled plasma mass- spectrometer (ICP-MS to estimate the heavy metals and observed that the heavy metals like lead, and Cd were almost within WHO permissible limits. The Compound was analysed for organoleptic tests. The pH of compound was 2.95 and acidic in nature. The compound was negative for carbohydrates and starch & positive to tests of aikaloids, steroids, proteins, Glycosides, tannins, phynolics and Flavonides determined by phytochemical screening. The presence of bioactive compounds (after phytochemical tests in the drug has been linked to their activities against disease causing microorganisms and also offering the plants to protect themselves against infections by pathogenic microorganisms.
Full Text Available Myrica nagi belongs to myricaceae family. It is commonly known as Bay berry (English and Kathphal (Hindi. Myrica nagi has a long history of usage in traditional medicine against various ailments. In Ayurvedic and other traditional medicinal practices the plant has been used against diseases like, fever, Cardiac debility, typhoid, diarrhoea, dysentery. Phytochemicals like glycosides, saponins tannins, flavonoids, triterpenes and sterols have been isolated. Important pharmacological activities such as hepatoprotective, antioxidant, antibacterial, antifungal, antihelmintic, antiinflammatory and antiasthmatic properties were shown by researchers. This review presents a detailed survey of the literature on various traditional uses, phytochemical and pharmacological properties of Myrica nagi.
Anantkumar V. Shekokar
Full Text Available Since Vedic period Homa-havana and Yadnya, sterilization of air by Agnihotra, sterilization of house & place around it by Dhoopan, is going on traditionally. Also it is useful in branches of Ayurveda like Shalya, Shalakya, Kaumarbhrutyat and Prasutistreeroga. Sushruta has also explained the method of treating Vrana, Vranitaagara and Shastrakarmaghruha by this method of Dhoopana. Hence present experimental study was planned to study the efficacy of Ayurvedic Dhoopana Dravya like Guggulu, Aguru, Sarjarasa and Sarshapa, added with Lavana, Nimbapatra & Ghee. After Dhoopan process swab were collected & send to laboratory for testing and significant results was obtained.
Subrata De et al
Full Text Available Panchagavya, a classical Ayurvedic preparation, was evaluated for its antioxidant potential by HPTLC-DPPH bioautography method as well as assays for Ferric reducing antioxidant power (FRAP, DPPH – free radical scavenging activity (DPPH and Superoxide radical scavenging activity. In addition total phenolic content was also estimated which was in fairly good amount. HPTLC-DPPH bioautography study revealed the presence of several antioxidant compounds in Panchagavya. In all the assays performed, it showed considerable antioxidant activity. On comparison of the data of three different batches of the samples studied, it showed 98.3 - 99.8% correlation between total phenolic content, FRAP and DPPH assays.
... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...
Ameeta Ravi Kumar; Shobha Bhargava; Smita Zinjarde; Remya Ravindran; Sudha Ponnusamy
Pancreatic α-amylase inhibitors offer an effective strategy to lower the levels of post prandial hyperglycemia via control of starch breakdown. Eleven Ayurvedic Indian medicinal plants with known hypoglycemic properties were subjected to sequential solvent extraction and tested for α-amylase inhibition, in order to assess and evaluate their inhibitory potential on pancreatic α-amylase. Analysis of 91 extracts, showed that 10 exhibited strong Human Pancreatic Amylase (HPA) inhibitory potential...
Aswathy Aromal, S.; Dinesh Babu, K. V.; Philip, Daizy
The development of new synthesis methods for monodispersed nanocrystals using cheap and nontoxic chemicals, environmentally benign solvents and renewable materials remains a challenge to the scientific community. The present work reports a new green method for the synthesis of gold nanoparticles. Four different ayurvedic arishtams are used for the reduction of Au3+ to Au nanoparticles. This method is simple, efficient, economic and nontoxic. Gold nanoparticles having different sizes in the range from 15 to 23 nm could be obtained. The nanoparticles have been characterized by UV-Visible spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD) and FTIR analysis. The high crystallinity of nanoparticles is evident from bright circular spots in the SAED pattern and peaks in the XRD pattern. The synthesized gold nanoparticles show good catalytic activity for the reduction of 4-nitrophenol to 4-aminophenol by excess NaBH4. The synthesized nanoparticles are found to exhibit size dependent catalytic property, the smaller nanoparticles showing faster activity.
Full Text Available Asthma is one of the most prevalent chronic inflammatory lung diseases among children and adults. A lot of work had been done in various field (including both modern and Ayurvedic on anti-asthmatic drugs to evaluate their action on lungs. The parameters chosen for assessing the properties of drug is mainly based on clinical improvement and improvement in pulmonary function test. These all method employed so far are indirect method for assessment of action of drug on lungs as change in pulmonary function may appear without any relevant change in lungs mechanics. In present study we assess the anti-asthmatic effect of drug directly on respiratory parameter by using MATLAB lung mechanics modeling. Administration of drug is equally distributed throughout lungs and produces significant increase in lung volume which is attributed to the decrease in airways resistance and increase in lung compliance.
Ilkay Erdogan Orhan
Full Text Available This paper covers the studies relevant to neuroprotective activity of Centella asiatica (L. Urban, also known as “Gotu Kola.” The plant is native to the Southeast Asia and has been used traditionally as brain tonic in ayurvedic medicine. The neuroprotective effect of C. asiatica has been searched using the key words “Centella, Centella asiatica, gotu kola, Asiatic pennywort, neuroprotection, and memory” through the electronic databases including Sciencedirect, Web of Science, Scopus, Pubmed, and Google Scholar. According to the literature survey, C. asiatica (gotu kola has been reported to have a comprehensive neuroprotection by different modes of action such as enzyme inhibition, prevention of amyloid plaque formation in Alzheimer’s disease, dopamine neurotoxicity in Parkinson’s disease, and decreasing oxidative stress. Therefore, C. asiatica could be suggested to be a desired phytopharmaceutical with neuroprotective effect emerged from traditional medicine.
Shah, Jigna Samir; Goyal, R. K.
Objective: The aim of the study was to explore the trends and rationale of use of memory and vitality-enhancing medicines (MVEM) in the Gujarat region. Materials and Methods: A prospective pharmacoepidemiological study involving pharmacists of Gujarat region was carried out in the year 2005. Pharmacists (n = 351) working in general and Ayurvedic medical stores were selected from 12 districts of Gujarat region. The pharmacists were explained about the objective of the study and were given a pr...
Deole, Yogesh S.; Chavan, Sulakshan S.; Ashok, B. K.; Ravishankar, B.; Thakar, A.B.; Chandola, H. M.
In recent years, many Ayurvedic formulations are being researched to provide an effective antidepressant and anxiolytic drug in the field of psycho-pharmacology. The present study was planned to evaluate the anti-depressant and anxiolytic activity of Rasayana Ghana Tablet comprising three herbs Guduchi (Tinospora cordifolia Miers), Aamalaki (Emblica officinalis Garten) (RGT) and Gokshura (Tribulus terrestris Linn). Swiss albino mice were divided into four groups of six animals each, comprisin...
Hullatti K; Sharada M
Standardization of herbal drugs based on their chemical and biological activity profile is an important prerequisite for acquiring the herbal market. The main problem encountered in standardization of Ayurvedic drugs is proper identification of the source plant. The present study was aimed to establish identification characters, quality control parameters, chemical and biological parameters for roots of three plants Cissampelos pareira, Cyclea peltata and Stephania japonica (Fam. Menispermace...
L. Ramesh; K. Madhava Chetty
“Kakanasa” an Ayurvedic drug used as emetic, and controls edema, haemorrhaids, vitiligo and other skin diseases is formulated with plant (root, stem, leaves) extracts of Asclepias curassvica. Because of number of factors the botanical specimens were adultered or contaminated and these adulterations can potentially alter the results in clinicals and reports causing suitable variations to have effects on quality, efficacy of these botanical supplements: we focused pharmacognostical studies of o...
Hausman, Gary J
Historical studies of homeopathy in Europe and the USA have focused on practitioners' attempts to emphasize 'modern' and 'scientific' approaches. Studies of homeopathy in India have focused on a process of Indianization. Arguing against such unilineal trajectories, this paper situates homeopathy in South India within the context of shifting relations between 'scientific' and 'indigenous' systems of medicine. Three time periods are considered. From 1924 through 1934, homeopathy was singled out by Government of Madras officials as 'scientific', as contrasted with the 'indigenous' Ayurvedic, Siddha, and Unani systems of medicine. From 1947 through 1960, both 'indigenous' and 'scientific' interpretations of homeopathy were put forward by different factions. An honorary director of homeopathy proposed the Indianization of homeopathy, and its reconciliation with Ayurveda; this view conflicted with the Madras government's policy of expanding the 'scientific' medical curriculum of the Government College of Indigenous Medicine. It was not until the early 1970s that homeopathy was officially recognized in Tamilnadu State. By then, both homeopathy and Ayurveda had become conceptualized as non-Tamil, in contrast with promotion of the Tamil Siddha system of 'indigenous' medicine. Thus, constructs of 'indigenous' and 'scientific' systems of medicine are quite malleable with respect to homeopathy in South India. PMID:12638553
P. S. Jamadagni
Full Text Available Punarnava Mandur is an iron containing classical Ayurvedic formulation which was studied for repeated dose oral toxicity study in Wistar rats for 90 days. Total 48 Wistar rats (24 male and 24 female were selected based on the body weight and were randomly distributed into four groups followed by administration of Punarnava Mandur at the dose of 0, 90, 450, 900 mg/kg body weight for 90 consecutive days. Body weight, Weekly Feed and Water consumption, Clinical Chemistry, Hematology, Differential leukocyte Count, Reticulocyte count and Organ weights were recorded and analyzed statistically. At termination, rats were sacrificed, examined for gross pathological changes, organs were collected, weighed and processed for histopathological evaluation. There was no effect on body weights and feed consumption, no abnormal findings in the histopathological evaluation of high dose group animals but there was significant increase in weight of liver in females of high dose group as compared to control. Hence, the dose level 450 mg/kg of Punarnava Mandur was found as NOAEL (No Observable Adverse Effect Level. However, the NOEL (No Observed Effect Level could not be established. It was suggested to carry out a toxicity study at possible higher doses so as to establish target organ of toxicity.
Radhika K Varma
Full Text Available In Ayurvedic classical texts administration of potent psycho-physical rejuvenator formulations comes under Rasayana chikitsa which frees one of diseases, improves quality of life and delays senile degenerative changes. Eleven among the most commonly used anti-oxidant, adaptogenic potent, well established rejuvenator herbs viz., Hareetaki (Terminalia chebula Retz, Vibheetaki (Terminalia bellerica Roxb Amalaki (Emblica officinalis Linn, Guduchi (Tinospora cordifolia Miers, Gokshura (Tribulus terrestris Linn, Yashtimadhu (Glycyrrhiza glabra Linn, Tulasi (Ocimum sanctum Linn., Haridra (Curcuma longa Linn, Daruharidra (Berberis aristata DC, Shunthi (Zingiber officinale Rosc, Punarnava (Boerhavia diffusa L were administered along with unequal quantity of ghee and honey as Anupana (vehicle to delay senile changes and reverse cataract formation in the eyes. For the first time the herbal compound in the powder form was subjected to Pharmacognstical evaluation, physico-chemical screening, phyto-chemical analysis and HPTLC studies. The presence of Scalariform vessels, Acicular crystals, Border pitted vessel, Starch grains were the characteristic features observed in the microscopy. The Phyto-chemical analysis indicated presence of alkaloids, tannins, saponins, flavonoids and glycosides.
Full Text Available The incessant and vital need to discover new antimicrobial compounds with diverse chemical structures and novel mode of action is stimulated by the increasing failure of chemotherapeutics and expanded antibiotic resistance exhibited by pathogenic agents. In the present research work, antimicrobial activity of few plant extracts and ayurvedic samples were screened against bacteria. Phytochemical analysis of active plant extracts showed the presence of triterpenes, glycosides and flavonoids. Both aqueous and acetone extracts of Holoptelia integrifolia leaf and Barringtonia acutangula flower; and methanolic extract of Glycyrrhiza glabra and Meera powder exhibited activity against S. aureus. Aqueous mortar pestle and soxhlet extracts of B. acutangula flower exhibited activity against both P. aeruginosa and E. coli. Further, the ability to adhere and build biofilm was assessed in few biofilm formers at sub-MIC concentrations using the Microtiter plate assay and the Coverslip assay. Aqueous soxhlet and mortar pestle extract of B. acutangula flower and acetone overnight extract of H. integrifolia leaf exhibited antibiofilm activity against these organisms.
Full Text Available Ayurveda is known as the oldest healing science. Talisadi Churna is important in management of digestive and respiratory disturbances of all body types. It is having different ingredient which are having a wide range of uses in health maintenance. The quality control of Talisadi churna which will assist the regulatory authorities, scientific organizations and manufacturer in developing standards.Talisadi churna (TC1 is consist of the fine powders of Talisapatra, Dalchini, Ela, Pippali, Shunthi, Vamsa lochna in the ratio of 1:1. It is best remedy in acute, chronic and allergic bronchitis. It is very useful in acute exacerbation of asthma. In chronic asthma it reduces the frequency and severity of asthmatic attack. Talisadi churna sample was prepared in laboratory according to Ayurvedic formulary. This was evaluated by comparative analysis with the marketed formulations (TC2&TC3 for their extractive values (ethanol and distilled water, Micromeretic parameters (bulk density, true density, angle of repose and Carr’s Index and Phytochemical evaluation. The extractive values of Talisadi churna (TC1, TC2 and TC3 in water and ethanol is (12.15,11.33,11.18 and 12.92,11.54,11.35 respectively indicating the presence of almost polar and semi polar constituents in Talisadi churna. These analytical findings and data analysis revels that parameters like Extractive values, Presence of Phytoconstituents and micromeretic parameters all remains in close proximity for each batch of the Talisadi churna.
Rahul K Dumbre
Full Text Available Background: Ayurveda recommends several plants and plant preparation for conditions of urogenital disorders as per its principles. Objectives: Ayurvedic plants Tamala (Cinnamomum tamala; Daruhalad (Berberis aristata; Ativish (Aconitum heterophyllum were studied for mechanisms of prostatic hyperplasia induced in rats. Materials and Methods: Prostatic enlargement was induced in castrated rats by testosterone injection s.c. for 21 days and simultaneously plants were dosed orally daily. On day 22 rats were sacrificed and prostate was removed; weight and volume of prostate was measured; histopathology performed. Inflammation was induced by injecting carrageenan in rat hind paw and inhibition was studied by measuring rat paw oedema at different time points. Results: Tamala showed significant effect where it reduced prostatic enlargement and improved hyperplastic changes, while Daruhalad and Ativisha did not show any significant effect. All of them showed mild to moderate anti-inflammatory activity. Conclusion: Study concludes that Tamala may benefit in prostate disorder by virtue of inhibition of androgen mechanisms in prostate and modulating inflammatory mediators in prostate. Daruhalad and Ativisha did not show any effect in this model of prostate enlargement while the anti-inflammatory effect may propose one of the useful properties when included in various formulations.
Full Text Available Standardization of herbal drugs based on their chemical and biological activity profile is an important prerequisite for acquiring the herbal market. The main problem encountered in standardization of Ayurvedic drugs is proper identification of the source plant. The present study was aimed to establish identification characters, quality control parameters, chemical and biological parameters for roots of three plants Cissampelos pareira, Cyclea peltata and Stephania japonica (Fam. Menispermaceae which are being used as source of Patha, in the market. All the three plant were subjected for evaluation of quality control parameters as per WHO guidelines and root extracts and total alkaloidal fractions were subjected for HPTLC and HPLC fingerprinting analysis using a marker compound Bebeerine isolated from roots of Cissampelos pareira. The parameters studied clearly indicated the significant differences among the three plant materials. The roots of Cissampelos pareira can be distinguished from other two plants by presence of high concentration of alkaloids especially the presence of high concentration of pharmacologically active alkaloid bebeerine, which was found to be present in very low concentration in Stephania japonica and absent in roots of Cyclea peltata. The roots of Cyclea peltata were found to contain high concentration of saponins and comparatively in low concentration in Cissampelos pareira where as it was found to be absent in roots of Stephania japonica.
M. Hemanth kumar
Full Text Available Liposomal Encapsulation Technology (LET is the newest delivery method used by medical researchers to transfer drugs that act as healing promoters to the definite body organs. This form of delivery system offers targeted delivery of vital compounds to the body. It has been in existence since the early 70’s. Liposomal Encapsulation Technology is a state of the art method of producing sub-microscopic bubbles called liposomes, which encapsulate various substances. These phospholipids or “liposomes” form a barrier around their contents that is resistant to enzymes in the mouth and stomach, digestive juices, alkaline solutions, bile salts, and intestinal flora, found in the human body as well as free radicals. The contents of the liposomes are therefore shielded from degradation and oxidation. This protective phospholipid shield or barrier remains unharmed until the contents of the liposome are delivered right to the target organ, gland, or system where the contents will be utilized. Natural extracts are generally degraded because of oxidation and other chemical reactions before they delivered to the target site. Our research has shown liposomal encapsulated ayurvedic preparations have shown more stability and also more efficiency when compared to traditional preparations. Size of liposomes were measured around 85-200 nm.
Dwivedi, Amarprakash P.
Polydactyly is a most common congenital hand defects in which the hand has one or more extra fingers, commonly seen postaxial, that is, on the small finger side. It is usually treated by surgically removing the extra finger typically, when the child is between 1 and 2 years old. Prognosis after removal of extra digit is good if it occurs in isolation though not devoid of complications like scar formation, stiffness, instability, and late deformity which may need additional reconstructive surgery to recover full function and improve the hand's appearance. I have used “Ksharsutra,” an Ayurvedic-medicated thread coated with herbal alkaline drugs having simultaneous cutting and healing property, to remove extra finger in a child, whose parents were not willing to undergo surgery and asked for alternative treatment. “Ksahrsutra ligation” showed excellent result in postaxial polydactyly. The extra finger started necrosing within 24 hours and sloughed out in just 9 days with minimal scar formation. After observing the prognosis, I believe that more cases should be done to establish and promote this unique parasurgical procedure, “Ksharsutra” in the management of polydactyly. PMID:23930044
Singh Akhilesh Kumar
Full Text Available Human beings, in order to adjust themselves in the modest era, have been compelled to become fast and mechanical. This is the reason why they can’t give proper attention to daily and seasonal regimes, exercise and diet. This change in lifestyle is responsible for replacement of Shad-rasatmak Ahara by preserved and fast foods, bakery products, shift duties (i.e.Ratree jagran, stress. All these factors making them more and more susceptible for diseases generated by Agnimandya. According to them Mandagni is root cause of every disease. Due to this Mandagni Ahara-Pachan Kriya gets affected leading to production of Sama Ahara-Rasa which ultimately causes the Rasa Dhatwagni Mandya and Uttarottar Dhatu remains malnourished. Agni plays the key role in the process of bio-transformation. This is the reason why Ayurvedic Samhitas has given a lot of importance to Agni. The Ayu, Varna, Bala, Swasthya, Utsah, Buddhi, Kanti, Oja, Teja and Prana of human beings mainly depend on the status of Agni, because of this Agni should be kept in its Prakut state.
Badawi, Ramsey D.
Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)
NASA Aerospace Medicine overview - Aerospace Medicine is that specialty area of medicine concerned with the determination and maintenance of the health, safety, and performance of those who fly in the air or in space.
CHF - medicines; Congestive heart failure - medicines; Cardiomyopathy - medicines; HF - medicines ... You will need to take most of your heart failure medicines every day. Some medicines are taken ...
Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments
Vibha Dwivedi; Shweta Tiwary; Subhash C Lakhotia
Earlier we showed formulation-specific beneficial effects of dietary supplement of Ayurvedic Amalaki Rasayana (AR, a herbal formulation) and Rasa-Sindoor (RS, a mercury-based organo-metallic formulation) on various biological parameters in Drosophila, parallel to traditional Ayurvedic literature. These formulations also suppressed cell death and pathology in fly models of neurodegeneration. To understand basis of inhibition of apoptosis, we examined effects of AR and RS on induced and developmental apoptosis in Drosophila. Dietary AR or RS significantly reduced apoptosis induced by GMR-GAL4-, sev-GAL4- or hs-GAL4-directed expression of Rpr, Hid or Grim (RHG) pro-apoptotic proteins or by GMR-GAL4-directed DIAP1-RNAi, resulting in significant restoration of organism's viability and eye morphology. AR or RS supplement enhanced levels of inhibitor of apoptosis proteins, DIAP1 and DIAP2, and of Bancal/Hrb57A, while the levels of RHG proteins and of initiator Dronc and effecter Drice caspases were reduced in non-apoptotic wild type as well as in RHG over-expressing tissues. Levels of Dronc or Drice remained unaffected in cells developmentally destined to die so that developmental apoptosis occurred normally. Elevated levels of DIAPs and reduced levels of RHG proteins and caspases reflect a more robust physiological state of AR or RS fed organisms allowing them to tolerate greater insults without triggering the cell-death response. Such homeo-static effects of these Rasayanas seem to contribute to ‘healthy ageing’, one of their effects suggested in traditional Ayurvedic practices.
Full Text Available Introduction: Ayurveda is known for philosophical basis, and its approach to psychological ailments is quite different from conventional system of management. Satvavajaya Chikitsa (Ayurvedic psychotherapy is a nonpharmacological approach aimed at control of mind and restraining it from unwholesome Artha (objects or stressors. Withdrawal of the mind from unwholesome objects is known as Sattvavajaya Chikitsa or it is a treatment by Self Control. Charaka defines it as a mind controlling therapy in which a stress has been laid on restraining of mind from unwholesome objects. Thus, it includes all the methods of Manonigraha and Astanga Yoga (Yogic techniques too. Indian philosophy portrays Astanga Yoga as a primary tool to control mind; hence it can be used as Satvavajaya Chikitsa. Aims and Objectives: To evaluate efficacy of Satvavajaya Chikitsa and Aushadhiya Medhya Chikitsa for improving Smriti in young healthy volunteers. Materials and Methods: Totally, 102 physically healthy volunteers between age group 16 and 25 years were divided into two groups. In Group A, Satvavajaya Chikitsa was adopted in form of Yogic procedures such as Asana, Pranayama, Chanting etc., with counseling and placebo. Group B was Shankhapushpi tablets made with whole part of Shankhpushpi plant was used as standard control. The Weschler′s memory scale (WMS was adopted to collect data before and after intervention period of 2 months. Paired and Unpaired t-test were used for analysis the data in Sigmastat Software. Results: Group A (Satvavajaya + placebo with counseling showed statistically highly significant result (P < 0.001 in verbal retention for similar pair, verbal retention for dissimilar pair and visual immediate tests; while Group B (Shankhapushpi tablets showed significant result (P < 0.01 in auditory delayed, visual delayed, auditory recognition and visual recognition tests. Conclusion: Satvavajaya Chikitsa shows better results in immediate recollection in terms of
Amin, Hetal; Sharma, Rohit
Introduction: Ayurveda is known for philosophical basis, and its approach to psychological ailments is quite different from conventional system of management. Satvavajaya Chikitsa (Ayurvedic psychotherapy) is a nonpharmacological approach aimed at control of mind and restraining it from unwholesome Artha (objects) or stressors. Withdrawal of the mind from unwholesome objects is known as Sattvavajaya Chikitsa or it is a treatment by Self Control. Charaka defines it as a mind controlling therapy in which a stress has been laid on restraining of mind from unwholesome objects. Thus, it includes all the methods of Manonigraha and Astanga Yoga (Yogic techniques) too. Indian philosophy portrays Astanga Yoga as a primary tool to control mind; hence it can be used as Satvavajaya Chikitsa. Aims and Objectives: To evaluate efficacy of Satvavajaya Chikitsa and Aushadhiya Medhya Chikitsa for improving Smriti in young healthy volunteers. Materials and Methods: Totally, 102 physically healthy volunteers between age group 16 and 25 years were divided into two groups. In Group A, Satvavajaya Chikitsa was adopted in form of Yogic procedures such as Asana, Pranayama, Chanting etc., with counseling and placebo. Group B was Shankhapushpi tablets made with whole part of Shankhpushpi plant was used as standard control. The Weschler's memory scale (WMS) was adopted to collect data before and after intervention period of 2 months. Paired and Unpaired t-test were used for analysis the data in Sigmastat Software. Results: Group A (Satvavajaya + placebo) with counseling showed statistically highly significant result (P < 0.001) in verbal retention for similar pair, verbal retention for dissimilar pair and visual immediate tests; while Group B (Shankhapushpi tablets) showed significant result (P < 0.01) in auditory delayed, visual delayed, auditory recognition and visual recognition tests. Conclusion: Satvavajaya Chikitsa shows better results in immediate recollection in terms of short
Dhiman, K S; Dhiman, Kamini; Puri, Samita; Ahuja, Deepak
Ayurveda the science of life, since its origin is serving the mankind throughout in health & disease state of life. Shalakyatantra, one of its specialized branch deals with the science of Ophthalmology, Otorhinolaryngology, Orodental surgery & Head; was contributed and developed by Rajrishi Nimi, the King of Videha, who was a colleague of Atreya, Punarvasu, Dhanwantri, Bharadwaja, Kashyapa etc. The available literature related to this speciality is reproduced from original text of Nimitantra in Uttartantra of Sushruta samhita. So Rajrishi Nimi deserves all the credit and regards for Shalakyatantra and for being the first eye surgeon on this earth. The fact regarding the technique of cataract surgery adopted by ancient surgeons is still a matter of debate. Most of the medical fraternity accepts cataract surgery of ancient surgeons as couching procedure but after going through forth coming pages, the prevailing concept will prove to be a myth. It started with extra capsular extraction through small incision during the period of Sushruta Samhita but later shifted to couching like technique by Acharya Vagbhatta. Secondly, the objective of this literary research paper is to find proper co-relation of the disease cataract to those mentioned in Ancient Ayurvedic classic. Linganasha has been inadvertently taken as cataract but this is neither logical nor in accordance with classics. We find detailed description of cataract's differential diagnosis, indications, contra- indications, pre/intra/post operative procedures and complication in ancient texts of Ayurveda. Not only this, vivid description of treatment of various complications of cataract surgery are also given. Needless to say, no other surgically treatable diseases & its complications except Kaphaja Linganasha are given this much attention. PMID:22131692
Full Text Available Berberis lycium belong to family Berberidaceae is an evergreen shrub growing in Himalayan region. The various parts of the plant like root, bark, stem, leaves and fruits are used by the people as a medicine or food. This plant has also gained wide acceptance for its medicinal value in ayurvedic drugs. The plant is known to prevent liver disorders, abdominal disorders, skin diseases, cough, ophthalmic etc. Moreover the pharmacological studies have shown that plant is hypoglycemic, hyperlipidemic, hepatoprotective, anticarcinogenic and antipyretic properties. The fruits of the plant are also very nutritious and are rich source of vitamins, minerals, antioxidants, anthocyanin etc. These fruits are consumed in raw form or are utilized in the preparation of juices, jams, preserve etc. by the local inhabitants. In the present article an attempt has been made to summarize the various properties of Berberis lycium plant.
Leafy samples often used as medicine in the Indian Ayurvedic system and vegetables were analyzed for 20 elements (As, Ba, Br, Ca, Ce, Cr, Cs, Co, Eu, Fe, K, La, Na, Rb, Sb, Sc, Sm, Sr, Th, Zn) by employing Instrumental Neutron Activation Analysis (INAA). The samples were irradiated at the 100 kW TRIGA-MAINZ nuclear reactor and the induced activities were counted by gamma ray spectrometry using an efficiency calibrated high resolution High Purity Germanium (HPGe) detector. The concentration of the elements in the medicinal and vegetable leaves and their biological effects on human beings are discussed
Mishra, Ashish; Seth, Ankit; Maurya, Santosh Kumar
Diarrhea is a serious problem affecting 3-5 billion people per year around the world, especially children of below 5 years. 70% of the world population uses traditional and indigenous medicine for their primary health care. The facts of these indigenous remedies are passed verbally and sometimes as documents. Since ancient time, Ayurveda is the main system of healing in South East Asian countries. Indian literature from ayurvedic texts and other books claim the potency of several plants in the treatment of diarrhea. As the global prospective of ayurvedic medicine is increasing, interest regarding the scientific basis of their action is parallely increasing. Researchers are doing experiments to establish the relation between the claimed action and observed pharmacological activities. In the present article, an attempt was made to compile the scientific basis of medicinal plants used to cure diarrhea in Ayurveda. Literature was collected via electronic search (PubMed, ScienceDirect, Medline, and Google Scholar) from published articles that reports antidiarrheal activity of plants that were mentioned in Ayurveda classics. A total of 109 plant species belonging to 58 families were reported for their antidiarrheal activity. Several Indian medicinal plants have demonstrated promising antidiarrheal effects, but the studies on the antidiarrheal potentials of these plants are not taken beyond proof of concept stage. It is hoped that the article would stimulate future clinical studies because of the paucity of knowledge in this area. PMID:27366356
Disayavanish, C; Disayavanish, P
Thai traditional medicine is one of the most valuable heritages handed down from Thai ancestors. In spite of increasing popularity of Western modern medicine, Thai traditional medicine is still widely used in taking care of health in daily life especially among the rural Thais. For the past decade, the government and private organizations have worked in collaboration to restore the values and popularity of Thai traditional medicine. Recently, the Ministry of Public Health has promoted the use of herbal medicine, and the Center for Herbal Information has collected data and performed scientific studies on this matter. Thai Massage Restoration Project has also revised the text on Thai traditional massage, which is now widely practised. The future prospects of Thai traditional medicine are rather positive because the Foundation for Restoring Thai Traditional Medicine and the College of Ayurvedic Medicine have the program and curriculum to produce personnel on traditional medicine. They have also attempted to integrate the basic knowledge of Western medicine into the study and practice of Thai traditional medicine. PMID:9895186
Full Text Available Allergic Rhinitis (AR is an immunoglobulin (Ig E mediated inflammatory disease caused by the inflammation of airway mucosa with hypersensitivity resulting from seasonal or perennial responses to specific allergens. Prevalence of AR is increasing and has risen considerably in the past few decades with self reported prevalence up to 41%. According to Ayurvedic texts indication of Anutaila (classical Ayurvedic oil preparation used in the form of Pratimarsha Nasya a traditional nasal drug delivery system has been used for a long period has shown beneficial effects on diseases of head and neck. A pretest and post test design of single group consisting of 37 patientsdiagnosed as allergic rhinitis were administered Pratimarsha Nasya (PNwith Anutaila daily for a period of 60 days. Effect ofPratimarsha Nasya with Anutaila on the chief complaints and totals nasal symptom score showed ameliorative improvement with statistical significance. Laboratory immunological parameters which included Total Leucocyte Count, Absolute Eosinophil Count, Neutrophils and Lymphocytes showed improvement with high statistical significance (< 0.001. At the end after 60 days of medication the patients showed marked relief in symptoms which can open a new direction in Ayurveda inspired novel targeted drug delivery systems.
Sun, Chong; Nirmalananda, Swami; Jenkins, Charles E; Debnath, Shawon; Balambika, Rema; Fata, Jimmie E; Raja, Krishnaswami S
The concept of Ayurvedic expert guided drug discovery and development is defined and put to test systematically for the first time in literature. Western Science has explored only ~5% of the approximately 25,000 species of higher plants for drug leads. The ancient medical science of Ayurveda has however employed a much larger spectrum of plants for clinical treatment. Clerodendrum viscosum (CV), a commonly growing weed in the Indian subcontinent has been employed by S. Nirmalananda (Ayurvedic expert) for the treatment of cervical cancer. Here we isolate and characterize a water extract fraction (Cv-AP) from the root of CV and evaluate its anticervical cancer cell bioactivity. Our results indicate that Cv-AP possesses pro-apoptotic, anti-proliferative, and anti-migratory activity in a dose-dependent fashion against cervical cancer cell lines. In contrast, primary fibroblasts (control healthy cells), when exposed to similar concentrations of this extract, fail to undergo apoptosis and remain relatively unaffected. These findings suggest that Clerodendrum viscosum (CV) is a readily available source of components with potent anti-cancer activity and selective bioactivity against cervical cancer cells. The major component in CV-AP was identified as a glycoprotein via SDS Page and Concanavalin-A binding studies. This study serves to illustrate that systematic collaboration with Ayurveda is a practical and powerful strategy in drug discovery and development. PMID:23387970
Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends ...
... for its scent, flavor, or therapeutic properties. Herbal medicines are one type of dietary supplement. They are ... and fresh or dried plants. People use herbal medicines to try to maintain or improve their health. ...
V Kusum Devi
Full Text Available Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. Our country has a vast knowledge base of Ayurveda whose potential is only being realized in the recent years. However, the drug delivery system used for administering the herbal medicine to the patient is traditional and out-of-date, resulting in reduced efficacy of the drug. If the novel drug delivery technology is applied in herbal medicine, it may help in increasing the efficacy and reducing the side effects of various herbal compounds and herbs. This is the basic idea behind incorporating novel method of drug delivery in herbal medicines. Thus it is important to integrate novel drug delivery system and Indian Ayurvedic medicines to combat more serious diseases. For a long time herbal medicines were not considered for development as novel formulations owing to lack of scientific justification and processing difficulties, such as standardization, extraction and identification of individual drug components in complex polyherbal systems. However, modern phytopharmaceutical research can solve the scientific needs (such as determination of pharmacokinetics, mechanism of action, site of action, accurate dose required etc. of herbal medicines to be incorporated in novel drug delivery system, such as nanoparticles, microemulsions, matrix systems, solid dispersions, liposomes, solid lipid nanoparticles and so on. This article summarizes various drug delivery technologies, which can be used for herbal actives together with some examples.
Om Prakash Rout
Full Text Available This study presents a preliminary data of occurrence of elemental concentration in medicinal plants i.e Apium graveolens (seed, Sida cordifolia (root, Solanum surattense (whole plant, Tribulus terrestris(fruit and Withania somnifera (root used in Ayurveda, using Atomic absorption spectrometer (AAS following standard procedures. The elemental concentration i.e. Mn, Na, K, Cl, Ca, Cr, Co, Cu, Fe, Pb, Zn, Ni, Cd and Hg were found in various proportions. The data obtained from the study can be used to evaluate the potentiality of these plants in their used for Ayurvedic drugs
Full Text Available The concepts of EBM empower us to formulate appropriate clinical questions, appraise the literature using the hierarchy of evidence and apply the study results to their practice. With the ever increasing demands to adopt EBM in practice, healthcare providers require educational resources that present the concepts of the EBM, research methodology and guides to publishing medical research in a simple and easy to understand format. EBM also promotes critical thinking by clinicians. It requires that clinicians have the open-mindedness to look for and try new methods scientifically supported by the literature and it asks the clinical interventions be scrutinized and proven effective. In addition, EBM offers ways to critically evaluate the enormous amount of medical literature for value. In this way, clinical interventions and treatments are not just accepted because someone speaks of their anecdotal effectiveness, but a rigorous standard is applied to scientific data to determine whether the information has merit and applicability. Ayurveda is an Ancient Asian practice. It’s a traditional medical system used by a majority of India’s 1.1 billion populations. Ayurveda is being seen as a rich resource for new drug development by modern day pharmacologists. Ayurveda, the science of life is a branch of Atharvanaveda. It has eight specialized branches such as kayachikitsa (internal medicine, Salakya (ENT, salya tantra (ayurvedic surgery, Agada tantra (toxicology and forensic medicine, bhuta vidya (treatment of psychic diseases, kaumarabhrutya (paediatrics,rasayana tantra (rejuvenation treatments and vajikarana (aphrodisiacs.
Shah, Mayuri R; Mehta, Charmi S; Shukla, V D; Dave, Alankruta R; Bhatt, N N
Sandhigatavata is described under vatavyadhi in all ayurvedic classical texts. Osteoarthritis is the most common articular disorder which begins asymptomatically in the second and third decades and is extremely common by age 70. Here Matra Vasti (therapeutic enema) was given with Bala taila as Vasti is the best treatment for vatavyadhies. It has vatashamaka and rasayana properties. Indigenous compound drug containing Guggulu, Shallaki, Yastimadhu, Pippali, Guduchi, Nirgundi, Kupilu and Godanti was given in one group along with Matra Vasti. In this study, 33 patients of Sandhigatavata completed the treatment. Patients were randomly divided into two groups. Sixteen patients in Group-A (sarvanga Abhyanga-swedana + matravasti) and 17 patients in Group-B (sarvanga Abhyanga-swedana+ matravasti + indigenous compound drug). The results of the study indicate that the patients of both the groups obtained highly significant relief in almost all the signs and symptoms of Sandhigatavata. PMID:22131712
The article deals with the growth of nuclear medicine in India. Radiopharmaceuticals both in elemental form and radiolabelled compounds became commercially available in India in 1961. Objectives and educational efforts of the Radiation Medicine Centre setup in Bombay are mentioned. In vivo tests of nuclear medicine such as imaging procedures, dynamic studies, dilution studies, thyroid function studies, renal function studies, linear function studies, blood flow, and absorption studies are reported. Techniques of radioimmunoassay are also mentioned. (S.K.K.)
... AerobiKa® Cardiology Medications Anticoagulant Medicine Anticoagulants and Drug-Food Interactions COPD Medications Bronchodilators Anti-Inflammatories Antibiotics Managing Your Medications Devices ...
Bochner, Arthur P.
In "Narrative Medicine: Honoring the Stories of Illness," Rita Charon paints an original and humane portrait of what it can mean to be a doctor, to live a life immersed in sickness and dedicated to wellness. Charon drops the veil, inviting readers to look at the secret, subjective, emotional face of medicine, a zone of self-censored feelings and…
Rao Paramkusha Madupu; Khemani Naresh
Aswagandha (Withania somnifera) is a popularly known medicinal plant said in Ayurveda. It has been used to promote vigor and strength. The current ongoing researches are approving the plant can be useful in malignacies at various levels and with different mechanisms. An effort has been made in this paper to review such results focused at cancer therapy and management. Aswagandha (Withania somnifera) is also known as Indian ginseng proves to be a beacon for blinded minds of cancer sufferers.
Full Text Available Fennel, Foeniculum vulgare, one of the most common use in India kitchen as a spice and as well as in traditional medicine for its estrogenic, lactagouge, diuretic, antioxidant, immune booster and its usefulness in dyspepsia. The use of medicinal plants by the general population is an old and still widespread practice that makes studies of their correct identification are very essential. In the present study the fruit of the plant, raw materials, their oleo resins and marketed formulations was subjected to Standardization parameter viz macro-microscopic, physico-chemical, microbial, heavy metals and Thin Layer Chromatography to fix the quality standards of this drug. Anethole, an active compound of Foeniculum vulgare, was also analyzed in different samples of Foeniculum vulgare. The result shown that physicochemical parameters evaluated are useful in standardization, Heavy metals and microbial load for raw materials, oleoresins and finished formulations are found to be within the limit of WHO guidelines, indicating that they are free from pathogens and they are safe to be used in Indian System of medicine. The data obtained from the study would be useful in the identification of the fruits of Fennel and serve as standards. The above parameters studied, may be used as a tool for the correct identification and standardization of the plant also to test the adulterants if any.
The task of the Expert Committee was to review the technical development and efficacy of nuclear medicine methods and to recommend the best possible means of establishing nuclear medicine services at various levels of medical care in different countries. After reviewing the contributions which nuclear medicine can make, the various types of medical institutions and hospitals in existence, the requirements, organization and funding of nuclear medicine services, and the cost/effectiveness of nuclear medicine, a number of recommendations were made. IAEA and WHO should make information on existing methods of cost/effectiveness analysis widely available; invite governments to include a description of such analysis methods in training programmes of their health officers; assist in the acquisition of the necessary data; and encourage and eventually support actual applications of such analyses to carefully selected nuclear medicine procedures in varying medicosocial environments. They were further recommended to study possible ways of improving reliability and ease of servicing nuclear medicine equipment, and extent of possible local construction; the possibility of making available supplies of matched characterized reagents for radioimmunoassay and related techniques; and to study the advantages of establishing a network of collaborating centres on an international basis
Shukla, Pankaj; Pawar, R. M; ,
Purpose: Quality aspect and variability observed in physico-chemical characteristics and mineral content of ayurvedic herbomineral formulations from indian market w.r.t brihat vat chintamani rasa. Method: Each of the selected herbomineral formulation was thoroughly investigated for the variation in packaging material, label information, analytical parameters like moisture, pH, ash and mineral content such as Iron, Mercury, Gold, Copper and Zinc which play a crucial role in increasing the bioa...
Pawar R.K.; Sharma Shivani; Singh K.C.; Sharma Rajeev Kr.
A simple, rapid, selective and quantitative HPTLC method has been developed for determination of Andrographonin in Andrographis paniculata (Whole Plant) and its formulation-Kalmegh Navaya Loha. The alcoholic extract of Andrographis paniculata (Whole Plant) and its ayurvedic formulation-Kalmegh Navayas Loha samples were applied on TLC Aluminium plate pre coated with Silica gel60 GF254 and developed using Toluene : Ethyl acetate : Formic acid (5:4:1) v/v as a mobile phase. The plate was spr...
Adhvaryu, Meghna R; Reddy, Narshimha; Parabia, Minoo H
The anti-tumor activity and chemopreventive potential of four Ayurvedic herbs viz. Curcuma longa L., Ocimum sanctum L., Tinospora cordifolia (Wild) Miers ex Hook.f & Thomas and Zizyphus mauritiana Lam. were evaluated using Dalton Lymphoma ascites (DLA) tumor model in Swiss Albino mice. The outcome was assessed using survival time, peritoneal ascitic fluid (Tumor volume) and hematological indices as parameters. Animals were divided into five groups (n = 6) viz. one DLA control and four Herb + ...
R. T. Sane
Objective: The aim of the study was to have bio-analytical approach for detoxification process of two poisonous plant materials viz. Aconitum laciniatum (root) and Abrus precatorius (seed) which are used in Ayurvedic preparations.Materials and Methods: For both the species proximate analysis was carried out. For the same plants HPTLC fingerprinting was compared , before and after detoxification process, using triphala quath. Infra red spectral studies for Abrus precatorius species (red and wh...
Full Text Available Summary: The herb Cyperus rotundus L (Cyperaceae is used by the traditional medicine practitioners of ayurvedic medicine in India for CNS disorders like loss of memory, depression and epilepsy. Though some of these properties have been evaluated, stream lined scientific evaluation is lacking to support the possible association between CNS disorders and C. rotundus. The present study was carried out to identify and characterize the phytochemical constituents and metal contents of the medicinal plant C. rotundus and to determine its toxicity. Qualitative chemical analysis confirmed the presence of phenols, tannins, glycoside and flavonoids. Physiochemical analysis revealed that the herb C. rotundus has low ash value and moderate water and alcohol solubility. Metal analysis revealed the presence of metal contents copper, lead, nickel and cadmium. Characterization of constituents using TLC technique exhibited 6 fractions and HPTLC analysis exhibited 13 peaks. Acute toxicological studies showed no mortality or morbidity up to 2000mg/kg body weight in Wistar rats. Sub chronic toxicity study revealed that, food, water consumption and body weight of animals didn’t vary significantly. But the hematological parameters showed an increase in WBC count and Hemoglobin level. The kidney function and liver function didn’t change even after long term exposure. Industrial relevance: The herb Cyprus rotundus L (Cyperaceae is used by the traditional medicine practitioners of ayurvedic medicine in India for CNS disorders like loss of memory, depression and epilepsy. The present study scientifically evaluated the physiochemical and toxicological effects of C. rotundus. The results obtained will help in identification and isolation of bioactive constituents for new therapeutic targets Keywords: Cyperus rotundus; HPLC; thin layer chromatography; physicochemical analysis; Sub chronic toxicity study.
Ayurvedic medicines are widely consumed by Indian population both for treatment and good health Ayurvedic medicines are used in various forms like infusions, decoctions, powder, tablets, fermented decoction (Arishta) etc. Arishtas are prepared using plant extracts soaked in sugar or jaggery and are generally consume on regular basis for good health. Hence an effort was made to analyse the natural radioactivity in the Ayurvedic Arishtas. 213Po is an important naturally occurring radionuclide that volatilizes beyond 150℃. Hence adequate care is needed during sample pretreatment step. Both physical (freeze-drying, open vessel evaporation and microwave digestion) and chemical (digestion using various mineral acids like aqua regia, Con. HNO3, H2SO4 and oxidizing agents like H2O2 and HClO4) pretreatment procedures were adopted. After the initial sample treatment polonium radionuclide was pre-concentrated using calcium phosphate co-precipitation. Calcium phosphate precipitate was dissolved in 150 ml of 0.5M HCI solution with approximately 1 g of ascorbic acid for auto deposition of Polonium on silver planchette for 3 hours at 90℃ on a rotary hot plate. The sample sources were counted in calibrated alpha spectrometer with 450 mm2 low-back-ground PIPS detector interfaced with ECIL MCA. The spectrum analysis was done using PHAST Software. 209Po tracer, at low levels was added to the samples for assessing the radiochemical recovery. The recovery ranged between 18-83 %. The lowest recovery was obtained for the samples that were processed by open vessel digestion with HNO3 + HCIO4 + H2O2. The highest recover was for those samples that were freeze dried and subjected to HNO3 + HCIO4 + H2O2 acid digestion at 90℃ for 8 hours. 210Po concentration in a few samples varied between 0.3-3.5 mBq/L. The paper presents the results of radiochemical recoveries for different pretreatment methods and also the 210Po content in the ayurvedic arishtas. (author)
... CLPPP CAP Healthy Homes Assessment Tools Lead Health Literacy Initiative Refugee Tool Kit Resources Healthy Homes and ... As blood lead levels increase, so does lead’s effects on health. How to tell if herbal medicines ...
AJAY B. KHATRI
Full Text Available Indian government has taken initiative to preserve the Indian indigenous knowledge of medicinal and health care. Ayurveda is one of them. Today Ayurveda is getting name and fame worldwide. From some years Indian government has taken step by establishing AYUSH department. As the government put the faith on the AYUSH department, it is working very nicely. AYUSH establish some database portal for the access of Ayurveda research. TKDL, AYUSH research portal and DHARA are examples of them. The present paper is based on the features, facilities, structure and content of research portals and databases.
Despite an aggressive, competitive diagnostic radiology department, the University Hospital, London, Ontario has seen a decline of 11% total (in vivo and in the laboratory) in the nuclear medicine workload between 1982 and 1985. The decline of in vivo work alone was 24%. This trend has already been noted in the U.S.. Nuclear medicine is no longer 'a large volume prosperous specialty of wide diagnostic application'
Traditional Chinese medicine is becoming a new source of growth in China-Africa trade LIU Tao never expected that his traditional Chinese medicine (TCM) products would be so warmly welcomed at the annual Canton Fair last year.His surprise came after a large number of African businessmen expressed a keen interest in importing the products.That knowledge left a broad smile on his face.
... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...
Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...
... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...
Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...
Balasubramanian, Sai Venkatesh; Balasubramanian, Gomathi; Ramanathan, Ganapathy
Today, the world's ever-changing lifestyles demand a reliable, comprehensive system of integrative medicine with minimal side effects. One of the most prominent candidates for such a system is music, an enjoyable health care approach, and in response to the need for that system, the present article formulates one that is music based. Specifically, the authors have explored the physician-patient interaction, developing a model of that interaction within the context of music therapy. That model is based on ancient Ayurvedic principles and on research from modern physics and biology, such as that on quantum consciousness, chaos theory, the statistical theory of communication, information theory, and neurodynamics. The authors formulated 6 dimensions for that model: (1) physiological-Tridoshas, (2) emotional-Trigunas, (3) sociological-temperament, (4) psychological-brain waves, (5) spiritual-Chakras, and (6) informational-landscape. The connections between music and those dimensions are explored in the current article. The model opens the doors for a reliable, enjoyable, holistic health care, using music, with minimal side effects. PMID:27089526
Retief, F P; Cilliers, L
Although the Mesopotamian civilisation is as old as that of Egypt and might even have predated it, we know much less about Mesopotamian medicine, mainly because the cuneiform source material is less well researched. Medical healers existed from the middle of the 3rd millennium. In line with the strong theocratic state culture, healers were closely integrated with the powerful priestly fraternity, and were essentially of three main kinds: barû (seers) who were experts in divination, âshipu (exorcists), and asû (healing priests) who tended directly to the sick. All illness was accepted as sent by gods, demons and other evil spirits, either as retribution for sins or as malevolent visitations. Treatment revolved around identification of the offending supernatural power, appeasement of the angry gods, for example by offering amulets or incantations, exorcism of evil spirits, as well as a measure of empirical therapy aimed against certain recognised symptom complexes. Medical practice was rigidly codified, starting with Hammurabi's Code in the 18th century BC and persisting to the late 1st millennium BC. Works like the so-called Diagnostic Handbook, the Assyrian Herbal and Prescription Texts describe the rationale of Mesopotamian medicine, based predominantly on supernatural concepts, although rudimentary traces of empirical medicine are discernible. There is evidence that Egyptian medicine might have been influenced by Mesopotamian practices, but Greek rational medicine as it evolved in the 5th/4th centuries BC almost certainly had no significant Mesopotamian roots. PMID:17378276
Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian
Abstract Objective To define the practice of travel medicine, provide the basics of a comprehensive pretravel consultation for international travelers, and assist in identifying patients who might require referral to travel medicine professionals. Sources of information Guidelines and recommendations on travel medicine and travel-related illnesses by national and international travel health authorities were reviewed. MEDLINE and EMBASE searches for related literature were also performed. Main message Travel medicine is a highly dynamic specialty that focuses on pretravel preventive care. A comprehensive risk assessment for each individual traveler is essential in order to accurately evaluate traveler-, itinerary-, and destination-specific risks, and to advise on the most appropriate risk management interventions to promote health and prevent adverse health outcomes during travel. Vaccinations might also be required and should be personalized according to the individual traveler’s immunization history, travel itinerary, and the amount of time available before departure. Conclusion A traveler’s health and safety depends on a practitioner’s level of expertise in providing pretravel counseling and vaccinations, if required. Those who advise travelers are encouraged to be aware of the extent of this responsibility and to refer all high-risk travelers to travel medicine professionals whenever possible. PMID:25500599
Full Text Available Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its varied therapeutic potential, it has also been the subject of considerable modern scientific attention. The major chemical constituents of the Withania genus, the withanolides, are a group of naturally occurring C28-steroidal lactone triterpenoids built on an intact or rearranged ergostane framework, in which C-22 and C-26 are appropriately oxidized to form a six-membered lactone ring. In recent years, numerous pharmacological investigations have been carried out into the components of W. somnifera extracts. We present here an overview of the chemical structures of triterpenoid components and their biological activity, focusing on two novel activities, tumor inhibition and antiangiogenic properties of withaferin A and the effects of withanolide A on Alzheimer's disease. The most recent attempts in biotechnological production of withanolides are also discussed.
Abdalla, Amir A; Smith, Robert E
Mercury has been determined in Ayurvedic dietary supplements (Trifala, Trifala Guggulu, Turmeric, Mahasudarshan, Yograj, Shatawari, Hingwastika, Shatavari, and Shilajit) by inductively coupled plasma-mass spectrometry (ICP-MS) and direct mercury analysis using the Hydra-C direct mercury analyzer (Teledyne Leeman Labs Hudson, NH, USA). Similar results were obtained from the two methods, but the direct mercury analysis method was much faster and safer and required no microwave digestion (unlike ICP-MS). Levels of mercury ranged from 0.002 to 56 μ g/g in samples of dietary supplements. Standard reference materials Ephedra 3240 and tomato leaves that were from the National Institute of Standard and Technology (NIST) and dogfish liver (DOLT3) that was from the Canadian Research Council were analyzed using Hydra-C method. Average mercury recoveries were 102% (RSD% 0.0018), 100% (RSD% 0.0009), and 101% (RSD% 0.0729), respectively. Hydra-C method Limit Of Quantitation was 0.5 ng. PMID:23710181
Gogtay, N J; Bhatt, H A; Dalvi, S S; Kshirsagar, N A
Non-allopathic Indian medicines, referred to elsewhere in the world as complementary and alternative medicine have gathered increasing recognition in recent years with regard to both treatment options and health hazards. Ayurveda, Siddha, Unani and homeopathy are practiced in India as non-allopathic systems. These systems comprise a wide range of therapeutic approaches that include diet, herbs, metals, minerals, precious stones and their combinations as well as non-drug therapies. Ayurveda is the oldest system of medicine in the world and by far the most commonly practiced form of non-allopathic medicine in India, particularly in rural India, where 70% of the population lives. The difference between modern medicine and these systems stems from the fact that the knowledge base of many of the above systems, unlike Western medicine, is based on years of experience, observations, empiricism and intuition and has been handed down generations both through word of mouth and treatises. The focus on non-allopathic systems of medicine in India can be attributed to various causes including a need to revive a rich tradition, the dependency of 80% of the country's population on these drugs, their easy availability, increasing worldwide use of these medicines, the lack of focused concerted scientific research and the abuse of these systems by quacks. Elsewhere, the increasing use of herbal products worldwide and the growth of the herbal product industry has led to increasing concern regarding their safety. The challenges in these non-allopathic systems relate to the patient, physician, regulatory authorities, the abuse/misuse of these medicines, quality and purity issues. Safety monitoring is mandated by a changing ecological environment, the use of insecticides, new manufacturing techniques, an as yet unregulated pharmaceutical industry, the availability of combinations of herbs over the counter and not mentioned in ancient Ayurvedic texts, and the need to look at the active
Tibetan medicine companies in T.A.R can manufacture more than 360 Tibetan patent medicines. There are 18 Tibetan medicine factories in Tibet, and total out value exceeds 3 billion yuan. 24 kinds of Tibetan patent medicines have been incorporated into State Fundamental Medicine List, in which 14 Tibetan patent medicines are listed in national protected traditional medicine category.
... other strategies that don’t use medicine have • Call the ADEAR Center toll-free: 1-800-438-4380 been tried. ... dose, patient’s name, dosage frequency, and expiration date. • ... Disease Education and Referral (ADEAR) Center is a service of the National Institute on ...
Phillipson, J. David
Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)
Lindequist, U.; Won Kim, H.; Tiralongo, E.; Griensven, van L.J.L.D.
Since beginning of mankind nature is the most important source of medicines. Bioactive compounds produced by living organisms can be used directly as drugs or as lead compounds for drug development. Besides, the natural material can be used as crude drug for preparation of powder or extracts. Plants
Belzberg, Allan S.
Nuclear medicine utilizes radioisotopes to diagnose and in some cases treat disease. Modern instruments can image their accumulation in an organ and provide quantitative data when indicated. The strength of these procedures is in the unique physiologic information they provide, rather than the presentation of precise anatomic detail.
The document contains two articles dealing with the radioisotope scintigraphy of myocardium and gullet and forty-one abstracts of papers presented at the seminar ''Twenty-nine Days of Nuclear Medicine'' held in Olomovc, September 29 - October 1, 1992. The contributions, all within the INIS subject scope, are input to INIS. (Z.S.)
engineered anti-TNF-alpha antibody constructs now constitute one of the heaviest medicinal expenditures in many countries. All currently used TNF antagonists may dramatically lower disease activity and, in some patients, induce remission. Unfortunately, however, not all patients respond favorably, and safety...
C V Sruthi
Full Text Available Background :The five kashayams (kwaths - decoctions Manjishtadi kashayam (MK, Rasna erandadi kashayam (REK, Sahacharadhi kashayam (SK, Maharasnadi (or Rasna dwiguna bhagam kashayam (MRK and Dhanwantharam kashayam (DK are widely used in the management of diseases manifested due to vitiation of vata and vatarakta (mostly diseases of connective tissues, bones, joints and nervous system. Free radicals are generated subsequent to the inflammatory changes in such conditions, and these cytotoxic reactive oxygen species cause oxidative damage to the cells. Phenolic compounds are the most common water soluble antioxidant compounds in plants. Objective : The present study aims at evaluating the phenolic content and antioxidant properties of these five kashayams and their probable protective role in the management of vata vyadhis. Materials and Method : The total phenolic contents of these five Ayurvedic decoctions were determined using Folin-Ciocalteu method and the antioxidant properties were estimated by DPPH (2′2-diphenyl-1-picryl hydrazine radical scavenging activity. Result : MK exhibited higher property (total phenolic content-15.61 ± 0.006 mg/g wt, EC50-7.2μg/ml when compared to other kashayams. DK with phenolic content 12.056 ± 0.004 mg/g wt and 22 μg/ml effective concentration for 50% inhibition comes next in the present study. REK, SK and MRK show almost similar phenolic content and antioxidant property. Conclusion : From the observations, it is seen that the total phenolic content and the antioxidant property of the products justify the protective and corrective effects produced by the products in vata and vatarakta disorders.
Pawson, Tony; Linding, Rune
To more effectively target complex diseases like cancer, diabetes and schizophrenia, we may need to rethink our strategies for drug development and the selection of molecular targets for pharmacological treatments. Here, we discuss the potential use of protein signaling networks as the targets...... for new therapeutic intervention. We argue that by targeting the architecture of aberrant signaling networks associated with cancer and other diseases new therapeutic strategies can be implemented. Transforming medicine into a network driven endeavour will require quantitative measurements of cell...... signaling processes; we will describe how this may be performed and combined with new algorithms to predict the trajectories taken by a cellular system either in time or through disease states. We term this approach, network medicine....
... Safe Use of Medicines Heath and Aging Safe Use of Medicines Introduction Read this booklet for practical ... Alice talk about medicine safety Related Publications Medicines: Use Them Safely Dietary Supplements Alzheimer's Disease Medications Fact ...
... Help a Friend Who Cuts? Complementary and Alternative Medicine KidsHealth > For Teens > Complementary and Alternative Medicine Print ... replacement. continue How Is CAM Different From Conventional Medicine? Conventional medicine is based on scientific knowledge of ...
Partial medication compliance, where patients do not take enough of their prescribed medicine to achieve adequate outcomes, is common. Research using electronic monitoring to assess compliance has shown that people take approximately 75% of doses as prescribed, irrespective of the condition being treated or its severity. Erratic compliance often leads to discontinuation of therapy, as treatment is perceived to be ineffective. Compliance decreases as frequency of dosing increases. Inadequate c...
Personcentreret medicin tager udgangspunkt i den person, lægen møder, hvad enten vedkommende er rask eller syg, og bygger på værdier som fortrolighed, kontinuitet, nærvær, tillid og tilgængelighed. Det er patientens dagsorden, der gælder, og lægen kan i fællesskab med patienten (baseret på en...
Smit Sibinga CT
Full Text Available Cees Th. Smit Sibinga ID Consulting, Zuidhorn, The NetherlandsTransfusion Medicine is a bridging science, spanning the evidence-based practice at the bedside with the social sciences in the community. Transfusion Medicine starts at the bedside. Surprisingly, only recently that has become rediscovered with the development of ‘patient blood management’ and ‘patient centered’ approaches to allow the growth of an optimal and rational patient care through supportive hemotherapy – safe and effective, affordable and accessible.1 Where transfusion of blood found its origin in the need of a patient, it has drifted away for a long period of time from the bedside and has been dominated for almost a century by laboratory sciences. At least the first ten editions of the famous and well reputed textbook Mollison’s Blood Transfusion in Clinical Medicine contained only a fraction on the actual bedside practice of transfusion medicine and did not focus at all on patient blood management.2 This journal will focus on all aspects of the transfusion chain that immediately relate to the bedside practice and clinical use of blood and its components, and plasma derivatives as integral elements of a human transplant tissue. That includes legal and regulatory aspects, medical, ethical and cultural aspects, pure science and pathophysiology of disease and the impact of transfusion of blood, as well as aspects of the epidemiology of blood transfusion and clinical indications, and cost-effectiveness. Education through timely and continued transfer of up to date knowledge and the application of knowledge in clinical practice to develop and maintain clinical skills and competence, with the extension of current educational approaches through e-learning and accessible ‘apps’ will be given a prominent place.
Mason, Cindy; Mason, Earl
The paper introduces haptic medicine--healthcare based on loving touch for healing and preventing disease. We describe the effects of loving touch (a square inch of our skin has over 1000 nerves) on the body, brain and mind. We describe two web-based health education and media projects. The first, HYPERLINK "http://www.21stcenturymed.org" www.21stcenturymed.org is a place for health practitioners to start learning about touch and resources. The second project, Humans Without Borders, is a multi-lingual self help education website for everyday people. Teaching materials for these projects are based on our previous work with a form of haptic medicine known as psychophysiophilosophy with patients at Stanford Hospital, Kaiser Permanente and Lucille Packard Children's Hospital. We describe psychophysiophilosophy, relate motherly love to recent discoveries in neurosciences and give hints on ways to increase motherly love in each of us. We present a plan for moving into the future by re-introducing haptic medicine into our daily lives through self-help and as an adjunct for current physician practice. There is an exercise in self-help for the reader and an appendix of recent clinical research with profound benefits on the use of human touch for over 40 conditions. PMID:19745495
Except for dedicated devices for mobile nuclear cardiology for instance, the market is set on variable angulation dual heads cameras. These cameras are suited for all general applications and their cost effectiveness is optimized. Now, all major companies have such a camera in their of products. But, the big question in nuclear medicine is about the future of coincidence imaging for the monitoring of treatments in oncology. Many companies are focused on WIP assessments to find out the right crustal thickness to perform both high energy FDG procedures and low energy Tc procedures, with the same SPECT camera. The classic thickness is 3/8''. Assessments are made with 1/2'', 5/8'' or 3/4'' crystals. If FDG procedures proved to be of great interest in oncology, it may lead to the design of a dedicated SPECT camera with a 1'' crustal. Due to the short half of FDG, it may be the dawning of slip ring technology. (e.g. Varicam from Elscint). The three small heads camera market seems to be depressed. Will the new three large heads camera unveiled by Picker, reverse that trend? The last important topic in nuclear medicine is the emergence of new flat digital detectors to get rid of the old bulky ones. Digirad is the first company to manufacture a commercial product based on that technology. Bichron, Siemens and General Electric are working on that development, too. But that technology is very expensive and the market for digital detection in nuclear medicine is not as large as the market in digital detection in radiology. (author)
R. T. Sane
Full Text Available Objective: The aim of the study was to have bio-analytical approach for detoxification process of two poisonous plant materials viz. Aconitum laciniatum (root and Abrus precatorius (seed which are used in Ayurvedic preparations.Materials and Methods: For both the species proximate analysis was carried out. For the same plants HPTLC fingerprinting was compared , before and after detoxification process, using triphala quath. Infra red spectral studies for Abrus precatorius species (red and white were compared, with respect to detoxification process. Protein fingerprinting was carried out for various Aconitum species available in the market. In support of the results obtained from the above methods for detoxification, safety evaluation , post single dose administration, C1- post single dose administration]was done using albino mice as the study model for Aconitum laciniatum (root and Abrus precatorius (seeds- red and white.Outcome Measures: Comparison of the results for the crude poisonous herbal material with the material obtained after detoxification in triphala quath. Results: HPTLC fingerprinting, Infra red spectral studies, safety evaluation study (animal toxicity showed that process of detoxification for the above mentioned plant materials using triphala quath is effective and less time consuming.Conclusions: The study highlights that the commonly used poisonous crude herbal materials viz. Aconitum laciniatum (root and Abrus precatorius (seeds - red and white can be safely used in Ayurvedic preparations, after detoxification using triphala quath.
Ignacio Briceño Balcázar
Full Text Available Until the twilight of the 20th century, genetics was a branch of medicine applied to diseases of rare occurrence. The advent of the human genome sequence and the possibility of studying it at affordable costs for patients and healthcare institutions, has permitted its application in high-priority diseases like cancer, cardiovascular disease, diabetes, and Alzheimer’s, among others.There is great potential in predictive and preventive medicine, through studying polymorphic genetic variants associated to risks for different diseases. Currently, clinical laboratories offer studies of over 30,000 variants associated with susceptibilities, to which individuals can access without much difficulty because a medical prescription is not required. These exams permit conducting a specific plan of preventive medicine. For example, upon the possibility of finding a deleterious mutation in the BRCA1 and BRCA2 genes, the patient can prevent the breast cancer by mastectomy or chemoprophylaxis and in the presence of polymorphisms associated to cardiovascular risk preventive action may be undertaken through changes in life style (diet, exercise, etc..Legal aspects are also present in this new conception of medicine. For example, currently there is legislation for medications to indicate on their labels the different responses such medication can offer regarding the genetic variants of the patients, given that similar doses may provoke adverse reactions in an individual, while for another such dosage may be insufficient. This scenario would allow verifying the polymorphisms of drug response prior to administering medications like anticoagulants, hyperlipidemia treatments, or chemotherapy, among others.We must specially mention recessive diseases, produced by the presence of two alleles of a mutated gene, which are inherited from the mother, as well as the father. By studying the mutations, we may learn if a couple is at risk of bearing children with the disease
Ignacio Briceño Balcázar
Full Text Available Until the twilight of the 20th century, genetics was a branch of medicine applied to diseases of rare occurrence. The advent of the human genome sequence and the possibility of studying it at affordable costs for patients and healthcare institutions, has permitted its application in high-priority diseases like cancer, cardiovascular disease, diabetes, and Alzheimer’s, among others. There is great potential in predictive and preventive medicine, through studying polymorphic genetic variants associated to risks for different diseases. Currently, clinical laboratories offer studies of over 30,000 variants associated with susceptibilities, to which individuals can access without much difficulty because a medical prescription is not required. These exams permit conducting a specific plan of preventive medicine. For example, upon the possibility of finding a deleterious mutation in the BRCA1 and BRCA2 genes, the patient can prevent the breast cancer by mastectomy or chemoprophylaxis and in the presence of polymorphisms associated to cardiovascular risk preventive action may be undertaken through changes in life style (diet, exercise, etc.. Legal aspects are also present in this new conception of medicine. For example, currently there is legislation for medications to indicate on their labels the different responses such medication can offer regarding the genetic variants of the patients, given that similar doses may provoke adverse reactions in an individual, while for another such dosage may be insufficient. This scenario would allow verifying the polymorphisms of drug response prior to administering medications like anticoagulants, hyperlipidemia treatments, or chemotherapy, among others. We must specially mention recessive diseases, produced by the presence of two alleles of a mutated gene, which are inherited from the mother, as well as the father. By studying the mutations, we may learn if a couple is at risk of bearing children with the
Nakanekar Amit Vishwas
Full Text Available Pre-diabetes is a ‘grey area’ between normal and diabetes. Various studies have shown that pre-diabetic subjects who developed diabetes had higher triglyceride and cholesterol values at baseline. At the time of diagnosis of diabetes around half of the patients will show some evidence of coronary artery disease. Treating dyslipidaemia in pre diabetes condition can not only reduce the conversion rate to diabetes but also occurrence of coronary artery disease (CAD. The Purpose of present study was to see whether an Ayurvedic polyherbal formulation PDBT which contains water extracts of Guduchi (Tinospora cordifolia, Vijaysar (Pterocarpus marsupium, Gudmar (Gymnemma sylvestre, Karvellak (Momordica charantia and Shunthi (Zinziber officinale can reduce mild to moderate dyslipidaemia in Pre-diabetic state as compared to placebo. A double blind placebo controlled (Randomized Controlled Trial RCT was conducted on 100 patients (50 in each group having mean age 48.78 ± 10.098; for 6 months to see the effect of polyherbal formulation as compared to placebo in pre-diabetic individuals. A diagnostic criterion for pre-diabetes was set according American Diabetic Association (ADA 2000. Cholesterol, High Density Lipoprotein (HDL, was done with Wyebenga and Pileggi’s method / Bio-lab Kit. Triglycerides were estimated by enzymatic Kit method. Blood sugar level (BSL was calculated by Glucose oxidase- peroxidase (GOD-POD method. Low Density lipoprotein (LDL, Very Low Density Lipoprotein (VLDL was calculated by formula. These investigations were done before treatment (BT and after treatment (AT. Unpaired T and paired T test were applied by INSTAT 2 software as a test of significance. Mean Cholesterol before treatment and after treatment 200.04 ± 41.6 and 172.09 ± 42.29, Mean HDL before treatment and after treatment 44.544 ± 10.517 and 47.30 ± 8.35, Mean LDL 116.37 and 92.91. Triglycerides before treatment and A. T. 160.16 ± 132.02 in PDBT treated group
Sharad Srivastava; Rawat, A. K. S.
Berberis aristata known as “Daruharidra” in Ayurveda is a versatile medicinal plant used singly or in combination with other medicinal plants for treating a variety of ailments like jaundice, enlargement of spleen, leprosy, rheumatism, fever, morning/evening sickness, snakebite, and so forth. A major bioactive marker of this genus is an alkaloid berberine, which is known for its activity against cholera, acute diarrhea, amoebiasis, and latent malaria and for the treatment of oriental sore cau...
A number of therapeutic uses of cannabis and its derivatives have been postulated from preclinical investigations. Possible clinical indications include spasticity and pain in multiple sclerosis, cancer-associated nausea and vomiting, cancer pain and HIV neuropathy. However, evidence is limited, may reflect subjective rather than objective outcomes, and is not conclusive. Controversies lie in how to produce, supply and administer cannabinoid products. Introduction of cannabinoids therapeutically should be supported by a regulatory and educational framework that minimises the risk of harm to patients and the community. The Regulator of Medicinal Cannabis Bill 2014 is under consideration in Australia to address this. Nabiximols is the only cannabinoid on the Australian Register of Therapeutic Goods at present, although cannabidiol has been recommended for inclusion in Schedule 4. PMID:26843715
Hvas, Lotte; Getz, Linn
Dagens allmänmedicin påverkas av ett växande managementtänkandetillsammans med fragmenterande ekonomiska incitament.Vårdens kvaliteter evalueras med nya metoder som ”värdebaseradvård” där värde räknas i kronor och ören. Produktion går före etik,och det intersubjektiva mötet mellan patient och läk...... läkare håller påatt nedvärderas. Perspektiven från narrativ medicin kan bidra tillatt visa vad som står på spel. Vilken blir annars berättelsen omallmänmedicinen?...
Full Text Available Liquoris, Glycyrrhiza glabra Linn, is a herb belonging to the family Leguminoceae.It is widely used in ayurvedic formulations. This review article is presented to phytochemical constituents and pharmacological activities, which were performed by widely different methods. It contains glycyrrhizin, which is a saponin glycoside, flavanoides, Carbenoxolone etc. Glycyrrhiza glabra Linn possesses different pharmacological activities such as antibacterial, antioxidant, antimalerial, expectorant, anti-tussive, antispasmodic, anti-inflammatory and anti hyper glycemic properties. Various other effects like antiulcer, antiviral, antihapatotoxic, antifungal and herpes simplex have also been studies. These results are very encouraging and indicate this herb should be studies more extensively to confirm these results and reveal other potential therapeutic effects. Medicinal uses of Glycyrrhiza glabra Linn through the millennia as well as drug-botanical interaction, side effect and toxicity also included under this review article.
... Order Search the NIGMS Website Search the NIGMS Website NIGMS Home Research Funding Research Training News & Meetings Science Education About NIGMS NIGMS Home > Science Education > Medicines By Design Medicines By Design Spotlight Nature's Medicine Cabinet A ...
... Use Medicines Safely Print This Topic En español Use Medicines Safely Browse Sections The Basics Overview Prescription ... all the medicines, vitamins, minerals, and herbs you use. Share this information with your doctor. Store your ...
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What is nuclear medicine? Nuclear medicine is a medical specialty that is used to diagnose and treat diseases in a safe and painless way. Nuclear medicine procedures permit the determination of medical information ...
... medical treatments that are not part of mainstream medicine. When you are using these types of care, it may be called complementary, integrative, or alternative medicine. Complementary medicine is used together with mainstream medical ...
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... this page: //medlineplus.gov/ency/patientinstructions/000570.htm Depression - stopping your medicines To use the sharing features ... prescription medicines you may take to help with depression, anxiety, or pain. Like any medicine, there are ...
Varanasi, Subhose; Narayana, A
The history of veterinary medicine is closely tied to the development of human medicine. Evidence of animal medicine has been found in ancient civilizations, such as those of the Hindu, Babylonians, Hebrews, Arabs, Greeks, and Romans. Ancient Indian literature in the form of the holy Vĕda, Purăna, Brăhmaņa, epics, etc. is flooded with information on animal care. The Purăņa are ancient scriptures discuss varied topics like devotion to God and his various aspects, traditional sciences like Ayurvĕda, Jyŏtişa (Astrology), cosmology, concepts like dharma, karma, reincarnation and many others. The treatment of animal diseases using Ayurvedic medicine has been mentioned in Garudapurăna, Agnipurăņa, Atri-samhită, Matsyapurăņa and many other texts. The Garudapurăņa is one of the important Săttvika purăna, the subject matter is divided into two parts, viz. Pŭrvakhaņda (first part) and an Uttarakhaņda (subsequent part). Gavăyurvĕda, Gajăyurvĕda narrated briefly and Aśvăyurvĕda described detailly in Pŭrvakhaņda. PMID:19580108
This article presents a brief history of nuclear medicine in France and describes the recent developments and equipment of the 3 techniques most used in hospital nuclear departments: 1) gamma-camera, 2) single photon emission computed tomography (SPECT), and 3) positron emission computed tomography (PECT). Concerning gamma-camera, a new design is being studied in a collaboration between the Saint-Gobain company and the LETI (a laboratory of Cea). In this innovative design the scintillator and the photomultiplier are replaced by a matrix of semi-conductor detectors based on CdZnTe crystal combined with an adequate electronic equipment. Concerning SPECT, many different techniques and equipment are used. Most improvements handle with the reduction of the survey time for the patient by using several detectors set on a ring around the patient. Concerning PECT, the developments follow 2 parallel ways: first the use of better scintillating materials for detecting 511 KeV photons (BGO: bismuth germanate, BaF2, LSO: lutetium orthosilicate, or GSO: gadolinium orthosilicate), and secondly the use of beta+ decay radionuclides that are more easily integrated in molecules similar to those present in the humane metabolism (18F through the fluorodeoxyglucose molecule). (A.C.)
... Teriparatide (Forteo); Denosumab (Prolia); Low bone density - medicines; Osteoporosis - medicines ... Osteoporosis is a disease that causes bones to become brittle and more likely to fracture (break). With ...
Full Text Available A simple, rapid, selective and quantitative HPTLC method has been developed for determination of Andrographonin in Andrographis paniculata (Whole Plant and its formulation-Kalmegh Navaya Loha. The alcoholic extract of Andrographis paniculata (Whole Plant and its ayurvedic formulation-Kalmegh Navayas Loha samples were applied on TLC Aluminium plate pre coated with Silica gel60 GF254 and developed using Toluene : Ethyl acetate : Formic acid (5:4:1 v/v as a mobile phase. The plate was sprayed (derivatized with Anisaldehyde- Sulphuric Acid reagent followed by heating at 1100C for 10 minutes and detection and quantification were carried out densitometrically using an UV detector at wavelength of 235 nm. Content of marker compound- Andrographonin found in the Andrographis paniculata (Whole Plant and its formulation-Kalmegh Navaya Loha were 0. 0.5194% w/w and 0.04966 % w/w respectively.
Pazzagli, M.; Malentacchi, F.; Mancini, I.;
Developments in "omics" are creating a paradigm shift in Laboratory Medicine leading to Personalised Medicine. This allows the increasing in diagnostics and therapeutics focused on individuals rather than populations. In order to investigate whether Laboratory Medicine is able to implement new...... diagnostic tools and expertise and commands proper state-of-the-art knowledge about Personalized Medicine and Laboratory Medicine in Europe, the joint Working Group "Personalized Laboratory Medicine" of the EFLM and ESPT societies compiled and conducted the Questionnaire "Is Laboratory Medicine ready...... for the era of Personalized Medicine?". 48 laboratories from 18 European countries participated at this survey. The answers of the participating Laboratory Medicine professionals indicate that they are aware that Personalized Medicine can represent a new and promising health model. Whereas they are aware...
Bassetti, Claudio; Dogas, Zoran; Peigneux, Philippe
The Sleep Medicine Textbook provides comprehensive, all-in-one educational material (550 pages) structured around the Catalogue of knowledge and skills for sleep medicine (Penzel et al. 2014, Journal of Sleep Research). Written by experts in the field and published by the ESRS, it provides an European approach to sleep medicine education, and represents the knowledge-base for the ESRS-endorsed sleep medicine examinations.The book is available at http://www.esrs.eu/esrs/sleep-medicine-textbook...
Gaire, Bhakta Prasad; Subedi, Lalita
Phyllanthus emblica L. (syn. Emblica officinalis) is commonly known as Indian gooseberry. In Ayurveda, P. emblica has been extensively used, both as edible (tonic) plants and for its therapeutic potentials. P. emblica is highly nutritious and is reported as an important dietary source of vitamin C, minerals and amino acids. All parts of the plant are used for medicinal purposes, especially the fruit, which has been used in Ayurveda as a potent Rasayana (rejuvenator). P. emblica contains phytochemicals including fixed oils, phosphatides, essential oils, tannins, minerals, vitamins, amino acids, fatty acids, glycosides, etc. Various pharmaceutical potential of P. emblica has been reported previously including antimicrobial, antioxidant, anti-inflammatory, analgesic and antipyretic, adaptogenic, hepatoprotective, antitumor and antiulcerogenic activities either in combined formulation or P. emblica alone. The various other Ayurvedic potentials of P. emblica are yet to be proven scientifically in order to explore its broad spectrum of therapeutic effects. On this regards we, in this review, tried to explore the complete information of P. emblica including its pharmacognosy, phytochemistry and pharmacology. PMID:25491539
Shrestha Keshab P
pharmacological findings, common Ayurvedic and earlier uses. Conclusions Although traditional herbal medicine is only a primary means of health care in far-west Nepal, the medicine has been pursued indigenously with complementing pharmacology and the Ayurveda. Therefore, further pharmacological evaluation of traditional herbal medicine deserves more attention.
Full Text Available Farm animals are reared for production to meet up the demand for animal protein in human. Various modern medicines are extensively used for production as well as treatment and prevention of diseases of animals, which can ultimately reach us through food chain. Herbs are now considered as an important source of alternative medicines. The Ayurvedic medicines prepared by manufacturers contain processed plant parts and added with preservative and other chemicals in many cases. The present way of research on herbal medicine follows the path of identification of active principles from the extracts of preserved parts of medicinal plants after testing of their efficacy in laboratory. This concept of research have the limitation of loss of many aromatic and other phytochemicals present in the living plant, which may have very important role when used together. Animals maintained in modern farm may be given relief from modern medicines in minor and moderate ailments, cure of problems related with their production with the validated fresh plant medicine available from the plants cultivated adjacent to the farm area. Consulting the reports of ethno-botanical study, a preliminary list of medicinal plant is prepared which are having antipyretic, analgesic, wound healing, immunostimulant, hepato-protective, fertility enhancing, pregnancy assisting, lactation assisting, anthelmintic, astringent, expectorant, purgative and anti-flatulent, nutriceutical, antiseptic, anti-dermatitis, anti-dysenteric and anti-enteric, hematenic, stomachic, diuretic and kidney stone removing effects and insecticidal or insect repelling effects. This list may be enriched further and plants may be selected for a farm from these groups according to the agro-climatic condition of the area, disease prevalence, problems encountered during farming practice and other requirements of the farm. Validation of reported effects of the plants is to be performed in fresh condition, so that parts
patients. Dehydroepiandrosterone is effective both in bipolar depression and depression in the setting of comorbid physical disease, although doses should be titrated to avoid adverse effects. Ayurvedic and homeopathic therapies have the potential to improve symptoms of depression, although larger controlled trials are needed. Mind-body-spirit and integrative medicine approaches can be used effectively in mild to moderate depression and in treatment-resistant depression. Currently, although CAM therapies are not the primary treatment of mood disorders, level 1 evidence could emerge in the future showing that such treatments are effective.Keywords: complementary and alternative medicine, mood disorders, Ayurveda, homeopathy, integrative medicine
Medicinal plants are important natural source of possibly secure drugs. They have been playing a significant role in mitigating human miseries by contributing herbal medicines in the primary health care systems of remote areas. About 70% population of rural and remote areas depends on folklore and traditional medicines to cure various ailments. The traditional medicines have gained much popularity due to the high cost and adverse effects of allopathic medicines which encouraged manufacturers of Greco-Arab and Ayurvedic systems of medicines to fuse their orthodox medicines with local traditional medicines in order to spread health coverage at a reasonable rate. Keeping in view the importance of ethnobotanical survey the current survey was carried out in Attock District, Punjab which comes under the Rawalpindi Division. The region has rural values of old civilizations and customs. The inhabitants of this area have their own trends for a village site, house, family, childbirth, death ceremonies, cultural functions, festivals and socio-religious belief. The ladies are more energetic and laborious as compared to gents. There is a lack of communication with current civilization which has kept them closer to nature from where they fulfill many of their daily needs. The inhabitants of the area are very close to natural flora, both in their habitat and livelihood. People of the area have speculative observations of nature and by communicating with other people of their culture, they discover the inherent knowledge of the local plants. As a result they gain indigenous knowledge, generation after generation. Plants and their derivatives available from the local area are utilized for many purposes such as food, fodder, medicine, veterinary medicines, timbers, households, oilseeds and also for socio-religious and various other purposes. In this way important medicinal plants are collected throughout the year for advertising, personal and entire community use. Due to random and
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Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... risk is very low compared with the potential benefits. Nuclear medicine diagnostic procedures have been used for ...
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The applications of nuclear energy on medicine, as well as the basic principles of these applications, are presented. The radiological diagnosis, the radiotherapy, the nuclear medicine, the radiological protection and the production of radioisotopes are studied. (M.A.C.)
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Langellier, Kristin M.
In this article, the author weaves narrative medicine and performance together to consider what might it mean to call narrative medicine a performance. To name narrative medicine as performance is to recognize the texts and bodies, the stories and selves, that participate in its practice--patients' and physicians' embodied stories as well as the…
Sharma, Priyanka; Parmar, Jyoti; Verma, Preeti; Sharma, Priyanka; Goyal, P K
Chemoprevention is an important strategy to control the process of carcinogenesis. The potential of using medicinal herbs as cancer chemopreventive nutraceuticals and functional food is promising. Thus, there is a need for exploring drugs/agents which act as chemopreventive agents. Phyllanthus niruri is a well known medicinal plant which has been used in Ayurvedic medicine as hepatoprotective, antiviral, antibacterial, analgesic, antispasmodic and antidiabetic. The present study was carried out to evaluate the anti-tumor activity of a hydro-alcoholic extract of the whole plant, in 7-9 week old male Swiss albino mice, on the two stage process of skin carcinogenesis induced by a single topical application of 7, 12-dimethylbenz (a)anthracene (100 microg/100 microl acetone) and two weeks later promoted by repeated application of croton oil (1% in acetone/three times a week) till the end of experiment (16 weeks). The oral administration of P. niruri at a dose of 1000 mg/kg/b.wt. at peri- (i.e. 7 days before and 7 days after DMBA application) and post- (i.e. starting from the croton oil application) initiational phase of papillomagenesis caused significant reduction in tumor incidence, tumor yield, tumor burden and cumulative number of papillomas as compared to carcinogen-treated controls. Furthermore, the average latent period was significantly increased in the PNE treated group. The results thus suggest that P. niruri extract exhibits significant anti-tumor activity, which supports the traditional medicinal utilization of this plant. PMID:20192590
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Chen, Ning-Hung; Hang, Liang-Wen; Lin, Chia-Mo
The sleep medicine is a young medical science in Taiwan. It began from less than 10 sleep beds 20 years ago in four hospitals all over Taiwan. By the organization of sleep team in Chang Gung Memorial Hospital and the initiation of Taiwan Society of Sleep Medicine, sleep medicine becomes a popular medicine in the past decades. The setting of Sleep Society in 2002 is the milestone to promote the sleep medicine, educate the public and professionals, and control of the quality of clinical practic...
De Lima, Joao Jose
Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it descr
Chaing, H S; Merino-chavez, G; Yang, L L; Wang, F N; Hafez, E S
Researchers have conducted considerable experiments on the effectiveness and therapeutic values of Chinese herbs and parts of plants. We should not ignore the significance of natural medicine. The Chinese have been perfecting medicinal therapy based on the raw ingredients of plants/herbs and their derivatives for thousands of years. Chinese practitioners of traditional medicine prescribe medicines based on yin and yang. Traditional medicine is communicated in a verb or written form. Natural resources used in traditional medicine to treat diseases are not limited to just medicinal plants but also include animals, shell fish, and minerals. Parts of plants used in traditional medicine are leaves, stems, flowers, bark, and root. Chinese medicine is the world's oldest continuous surviving tradition. The Chinese experimented with local plants, often resulting in mild to violent reactions. This process allowed them to become familiar with poisonous plants and those that could relieve pain or successfully treat illness. Current allopathic medicines are composed of synthetic compounds copied from natural chemical derivatives, which tend to be more potent than the original compound. Some medicinal plants used to effect conception/contraception include Striga astiatica (contraceptive); Eurycoma longifolia (male virility); and a mixture of lengkuas, mengkudu masak, black pepper seeds, ginger, salt, and 2 eggs (increase libido). Women in Malaysia take jamu to preserve their body shape and to provide nutrition during pregnancy. Praneem causes local cell-mediated immunity in the uterus. Clinical trials of Praneem with or without the hCG vaccine are planned. PMID:12287843
Alazraki, N.P.; Mishkin, F.S.
This guidebook for clinical nuclear medicine is written as a description of how nuclear medicine procedures should be used by clinicians in evaluating their patients. It is designed to assist medical students and physicians in becoming acquainted with nuclear medicine techniques for detecting and evaluating most common disorders. The material provides an introduction to, not a textbook of, nuclear medicine. Each chapter is devoted to a particular organ system or topic relevant to the risks and benefits involved in nuclear medicine studies. The emphasis is on presenting the rationales for ordering the various clinical imaging procedures performed in most nuclear medicine departments. Where appropriate, alternative imaging modalities including ultrasound, computed tomography imaging, and radiographic special procedures are discussed. Comparative data between nuclear medicine imaging and other modalities are presented to help guide the practicing clinician in the selection of the most appropriate procedure for a given problem.
Full Text Available Ayurvedic plants are known for thousands of years to have anti-inflammatory and antiarthritic effect. We have recently shown that BV-9238, a proprietary formulation of Withania somnifera, Boswellia serrata, Zingiber officinale, and Curcuma longa, inhibits LPS-induced TNF-alpha and nitric oxide production from mouse macrophage and reduces inflammation in different animal models. To evaluate the safety parameters of BV-9238, we conducted a cytotoxicity study in RAW 264.7 cells (0.005–1 mg/mL by MTT/formazan method, an acute single dose (2–10 g/kg bodyweight toxicity study and a 180-day chronic study with 1 g and 2 g/kg bodyweight in Sprague Dawley rats. Some sedation, ptosis, and ataxia were observed for first 15–20 min in very high acute doses and hence not used for further chronic studies. At the end of 180 days, gross and histopathology, blood cell counts, liver and renal functions were all at normal levels. Further, a modest attempt was made to assess the effects of BV-9238 (0.5 µg/mL on six major human cytochrome P450 enzymes and 3H radioligand binding assay with human hERG receptors. BV-9238 did not show any significant inhibition of these enzymes at the tested dose. All these suggest that BV-9238 has potential as a safe and well tolerated anti-inflammatory formulation for future use.
Recently, some plant extracts have been screened out against radiation and found to be quite promising. Aegle marmelos (Bael), belonging to family Rutaceae, fruits are very good source of proteins which form 5.12% of the edible portion. It is claimed to be useful in treating pain, fever, inflammation, respiratory disorders, cardiac disorders, dysentery and diarrhea. The ripe fruit is used for the treatment of digestive and stomachic complications. Aegle marmelos is a useful medicine for herbalist and it holds a reputed position in Ayurvedic system of medicine. Protection of intestinal constituents by Aegle marmelos extract (AME) was studied after exposure to 6 Gy gamma radiations in mice. For this purpose, Swiss albino mice were divided in various groups. Group I was administered with double distilled water (DDW), volume equal to AME (100 mg/kg body wt./animal), by oral gavage to serve as normal. Group II was administered orally AME extract once daily at a dose of 100 mg/kg b.wt./animal for 5 consecutive days. Group III was exposed to 6 Gy gamma radiations to serve as irradiated control. Group IV was treated with AME, orally for 5 consecutive days (as in Group-II), and were exposed to gamma radiation half an hour after the last administration of AME on day 5. Animals from all these group autopsied on 12 hrs, days 1, 3, 7, 15 and 30 post-treatment intervals
Nuclear medicine appears to be increasingly expanding both in its scope and its direct practical clinical usefullness. In view of the manifold possibilities offered by nuclear medicine this review has intentionally been very rapid and, if one will pardon the pun, a scunning approach to nuclear medicine applications. Only selected highlights in the expanding field of nuclear medicine were discussed. In the past 25 years nuclear medicine has emerged as an integrated medical discipline. It now plays a major role in patient management and has significantly expanded the physicians' diagnostic tools. As illustrated here, radionuclide procedures are currently applied in almost every medical speciality. In any event, the tests that comprise nuclear medicine have succeeded because they are rapid, effective, safe and insexpensive, and can be performed without discomfort for the patient. (orig.)
Dunn, Warren R; George, Michael S; Churchill, Larry; Spindler, Kurt P
Physicians have struggled with the medical ramifications of athletic competition since ancient Greece, where rational medicine and organized athletics originated. Historically, the relationship between sport and medicine was adversarial because of conflicts between health and sport. However, modern sports medicine has emerged with the goal of improving performance and preventing injury, and the concept of the "team physician" has become an integral part of athletic culture. With this distinction come unique ethical challenges because the customary ethical norms for most forms of clinical practice, such as confidentiality and patient autonomy, cannot be translated easily into sports medicine. The particular areas of medical ethics that present unique challenges in sports medicine are informed consent, third parties, advertising, confidentiality, drug use, and innovative technology. Unfortunately, there is no widely accepted code of sports medicine ethics that adequately addresses these issues. PMID:17218662
Nathanael Sabbah; Sinclair Wynchank
This article presents a description of tele-nuclear medicine and, after outlining its history, a wide, representative range of its applications. Tele-nuclear medicine has benefited greatly from technological progress, which for several decades has provided greater data transfer rates and storage capacity at steadily decreasing cost. Differences in the practice of nuclear medicine between developed and developing countries arise mainly from disparities in their available infrastructure, fundin...
Alazraki, N.P.; Mishkin, F.S.
The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth.
The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth
Donatella Lippi; Paolo Roberti di Sarsina; John Patrick D’Elios
Donatella Lippi1, Paolo Roberti di Sarsina2, John Patrick D’Elios11History of Medicine, Department of Anatomy, Histology, and Forensic Medicine, University of Florence, Florence, Italy; 2Health Local Unit, Department of Mental Health, Bologna, ItalyAbstract: Healing sounds have always been considered in the past an important aid in medical practice, and nowadays, medicine has confirmed the efficacy of music therapy in many diseases. The aim of this study is to assess the curative po...
Alkahtani, Saad Ahmed
Access to health care for children is important. It is dependent on access to health professionals and also parental attitudes towards illness. Children have the right to receive medicines that are scientifically evaluated for both efficacy and safety. Counterfeit and substandard medicines unfortunately result in the death of many children worldwide. There have been particular problems with diethylene glycol which has been used as a solvent in counterfeit medicines. It has also been foun...
Barnett, Huey D.
Physicians need support personnel for work with radioisotopes in diagnosing dangerous diseases. The Nuclear Medicine Technology (NMT) Program at Hillsborough Community College in Tampa, Florida, is described. (MW)
Full Text Available Donatella Lippi1, Paolo Roberti di Sarsina2, John Patrick D’Elios11History of Medicine, Department of Anatomy, Histology, and Forensic Medicine, University of Florence, Florence, Italy; 2Health Local Unit, Department of Mental Health, Bologna, ItalyAbstract: Healing sounds have always been considered in the past an important aid in medical practice, and nowadays, medicine has confirmed the efficacy of music therapy in many diseases. The aim of this study is to assess the curative power of music, in the frame of the current clinical relationship.Keywords: history of medicine, medical humanities, healing music
Majumdar, S K
The fall of the Roman Empire during the fifth century A.D. Ushered in the beginning of the Dark Ages. After this, in Europe further progress of Greco-Roman medicine originated from Hippocrates was halted. The ideas about medicine and hygiene were kept alive in monasteries only. The Arabs made advances in medicine at a time when the rest of Europe was in the Dark Ages. Islamic system or the rulers of the day actively encouraged scholarship and growth of knowledge. The Islamic gift of the day to the world of medicine was simply unique. PMID:12572570
A brief review is presented of the expanding horizons of nuclear medicine, the equipment necessary for a nuclear medicine laboratory is listed, and the value of this relatively new field to the veterinary clinician is indicated. Although clinical applications to veterinary medicine have not kept pace with those of human medicine, many advances have been made, particularly in the use of in vitro techniques. Areas for expanded applications should include competitive protein binding and other in vitro procedures, particularly in connection with metabolic profile studies. Indicated also is more intensive application by the veterinarian of imaging procedures, which have been found to be of such great value to the physician. (U.S.)
Dilip C; Saraswathi R; Krishnan PN; AK Azeem; Raseena; Abdul azeez; Ramya; Jaywin jose
Objective:To identify the chikungunya outbreaks in both indoor and outdoor patients in some selected hospitals in our locality and the burden and magnitude of the disease, to compare different system of medicines (allopathic, Ayurvedic, homeopathy etc) and to explore the knowledge, attitude and practices of pharmacists and other health care professionals in the treatment of chikungunya. Methods:A six-month study was carried out. Detailed history was taken from the case history, personal interview of doctors and suspected cases. Personal data such as name age, sex, location, date of onset of illness, medical history, general/systemic examination features, drugs used (allopathy, Ayurveda, homeopathy, or traditional) for the treatment, etc. were noted down. A simple questionnaire was prepared and distributed to various doctors practicing various systems of medicines. Results:A total of 209 suspected cases were identified from July to December, 2009. People in the age group of 20-40 years were more affected. The study revealed that females were more affected than males. The Grade-III (58.73%) population was more prone to chikungunya than Grade-II (38.75%) and Grade-I (2.87%). It showed that fever, pain in muscles, and sleeping disturbances were the intense symptoms of chikungunya. Myocarditis and arthritis were concomitant diseases which worsened chikungunya symptoms. It also indicated the effective medicine for compliance is nonsteroidal antiinflammatory drugs (NSAIDS). Conclusions:From our study we found that in some places there is no proper documentation, even though there are proper guidelines framed by the relevant authorities. It can be concluded from the study that all the systems of medicine are equally important for the management of chikungunya. Additional effort in promoting the guidelines at local level and proper documentation helps to achieve the goal of curbing the chikungunya. It is high time to increase our effort and promote these messages at
Complementary alternative medicines (CAMs), including food supplements, are taken widely by patients, especially those with cancer. Others take CAMs hoping to improve fitness or prevent disease. Physicians (and patients) may not be aware of the potential side-effects and interactions of CAMs with conventional treatment. Likewise, their known physiological effects could interfere with radiopharmaceutical kinetics, producing abnormal treatment responses and diagnostic results. Nuclear medicine physicians are encouraged to question patients on their intake of CAMs when taking their history prior to radionuclide therapy or diagnosis. The potential effect of CAMs should be considered when unexpected therapeutic or diagnostic results are found. (orig.)
Chiaramonte, Delia R; D'Adamo, Christopher; Amr, Sania
The University of Maryland Department of Epidemiology and Public Health collaborated with the Center for Integrative Medicine at the same institution to develop and implement a unique integrative medicine curriculum within a preventive medicine residency program. Between October 2012 and July 2014, Center for Integrative Medicine faculty provided preventive medicine residents and faculty, and occasionally other Department of Epidemiology and Public Health faculty, with comprehensive exposure to the field of integrative medicine, including topics such as mind-body medicine, nutrition and nutritional supplements, Traditional Chinese Medicine, massage, biofield therapies, manual medicine, stress management, creative arts, and the use of integrative medicine in the inpatient setting. Preventive medicine residents, under the supervision of Department of Epidemiology and Public Health faculty, led integrative medicine-themed journal clubs. Resident assessments included a case-based knowledge evaluation, the Integrative Medicine Attitudes Questionnaire, and a qualitative evaluation of the program. Residents received more than 60 hours of integrative medicine instruction, including didactic sessions, experiential workshops, and wellness retreats in addition to clinical experiences and individual wellness mentoring. Residents rated the program positively and recommended that integrative medicine be included in preventive medicine residency curricula. The inclusion of a wellness-focused didactic, experiential, and skill-based integrative medicine program within a preventive medicine residency was feasible and well received by all six preventive medicine residents. PMID:26477900
Side Effects of HIV Medicines HIV Medicines and Side Effects (Last updated 1/7/2016; last reviewed 1/7/2016) Key Points HIV medicines help people with ... will depend on a person’s individual needs. Can HIV medicines cause side effects? HIV medicines help people ...
Glerup, E; Dengsø, H
In connection with self-administration of medicine for patients with rheumatoid arthritis, patients with weak hands and elderly patients in general, the design of many medicine containers makes them awkward to handle for the patients. In this investigation 12 different medicine containers were tested. The 12 containers represent the antirheumatic medicine containers available on the market in Denmark in 1988. Sixty patients participated in the investigation. Thirty had rheumatoid arthritis and 30 had normal hand function. The age range was 40-85 years The patients had the choice between five possible answers concerning each container. In all patients, grip strength was measured. The patients with rheumatoid arthritis were classified in four functional classes, and pulpa-vola distance end thumb--5th MCP point distance were measured. The opening mechanisms of 29% of the antirheumatic medicine containers are unacceptable; these are plastic containers with a "push-off" top and suppository packs. 46%--(containers with screw cap or pressure dispensing) are considered acceptable. For 25% (tablet and capsule blister packs) the patients' estimate varied. It is important that medicine containers can be opened by the patients without difficulty, so that they do not present a hindrance to a correct intake of medicine or result in an unnecessary admission to hospital. The results of this investigation show that it is of continuous importance to encourage the production of medicine containers that comply with the requirements of the patients. PMID:2142351
Hosbach, Richard E.; Doyle, Robert E.
Study of pre-1750 medicine reveals that Iroquois diagnosis and treatment of disease was more advanced than the medicine of their European counterparts. The Iroquois developed a cure for scurvy, treated hypertension, and head lice, and even designed sauna baths. Indian psychiatry also included modern day techniques such as dream analysis. (MR)
PACS (Picture Archiving and Communication System) is being rapidly spread and installed in many hospitals, but most of the system do not include nuclear medicine field. Although additional costs of hardware for nuclear medicine PACS is low, the complexity in developing viewing software and little market have made the nuclear medicine PACS not popular. Most PACS utilize DICOM 3.0 as standard format, but standard format in nuclear medicine has been Interfile. Interfile should be converted into DICOM format if nuclear images are to be stored and visualized in most PACS. Nowadays, many vendors supply the DICOM option in gamma camera and PET. Several hospitals in Korea have already installed nucler PACS with DICOM, but only the screen captured images are supplied. Software for visualizing pseudo-color with color lookup tables and expressing with volume view should be developed to fulfill the demand of referring physicians and nuclear medicine physicians. PACS is going to integrate not only radiologic images but also endoscopic and pathologic images. Web and PC based PACS is now a trend and is much compatible with nuclear medicine PACS. Most important barrier for nuclear medicine PACS that we encounter is not a technical problem, but indifference of investor such as administrator of hospital or PACS. Now it is time to support and invest for the development of nuclear medicine PACS
... are the healthcare rituals practiced by a given culture (eg, Asian, Indian, African). Homeopathic Medicine: This alternative medicine system is based on the principle that “like cures like.” In other words, the same substance ... American Brain Tumor Association 8550 W. Bryn Mawr Ave. ...
Tripathi, Y.C.; Prabhu, V V; R S Pal; R N Mishra
Medicinal plants used in Indian system of medicine from Rajasthan state have been surveyed and catagorised systematically. The paper deals with 205 medicinal plants, thoroughly indexed along with their important traditional application for the cure of various ailments.
An analysis is given of the modern integrative medicine basis which is the synthesis of: 1. Theology, philosophy and sociology; 2. Physico-mathematical sciences, cybernetics, chemistry and astrology; 3. Medico-biological and clinical experience; 4. Traditional and scientific medicine; 5. Use of traditional and new medical technologies. Problems of 'holistic' medicine which considers Man as a unity of biological, emotional, psychological and social phenomena are exposed. Advantages in combining the drug therapy with modern physiotherapy and physioacupuncture methods seem to be obvious. All visible effects of a disease can de represented in the following forms of changes: information-energy - biochemical - ultrastructure - tissue - clinical diseases. Self-regulation of functional systems has a multilevel structure and needs application of different methods for body recovery. Short-wave irradiation (lasers, magnetotherapy) can be used for energy restoration in functional systems or meridians, and acupuncture plays the role of a 'trigger' which activises the body recovery. Integration of Western and Oriental medicines is the way for achieving the qualitative new level of health protection
... Orlando, FL AAOM: Representing the Discipline of Oral Medicine Oral Medicine is the discipline of dentistry concerned with the ... offers credentialing, resources and professional community for oral medicine practitioners. Our membership provides care to thousands We ...
Vedavathy, S.; Sudhakar, A; Mrdula, V.
Medicinal plants used in tribal medicine from chittoor district have been surveyed and documented systematically. The paper deals with 202 medicinal plants, indexed along with important tribal applications for the cure of various ailments.
... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...
... to Know About Zika & Pregnancy Complementary and Alternative Medicine KidsHealth > For Parents > Complementary and Alternative Medicine Print ... works. previous continue How CAM Differs From Traditional Medicine CAM is frequently distinguished by its holistic methods, ...
... Audience For Women Women's Health Topics Women and Diabetes - Diabetes Medicines Share Tweet Linkedin Pin it More sharing ... 1-800-332-1088 to request a form. Diabetes Medicines The different kinds of diabetes medicines are ...
Full Text Available ... by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease ...
Full Text Available ... produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ... I’d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify ...
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Gemmell, Howard G; Sharp, Peter F
Nuclear medicine plays a crucial role in patient care, and this book is an essential guide for all practitioners to the many techniques that inform clinical management. The first part covers the scientific basis of nuclear medicine, the rest of the book deals with clinical applications. Diagnostic imaging has an increasingly important role in patient management and, despite advances in other modalities (functional MRI and spiral CT), nuclear medicine continues to make its unique contribution by its ability to demonstrate physiological function. This book is also expanded by covering areas of d
Berral, Alessandro; Pira, Enrico; Romano, Canzio
In clinical medicine since some years overdiagnosis is giving rise to growing attention and concern. Overdiagnosis is the diagnosis of a "disease" that will never cause symptoms or death during a patient's lifetime. It is a side effect of testing for early forms of disease which may turn people into patients unnecessarily and may lead to treatments that do no good and perhaps do harm. Overdiagnosis occurs when a disease is diagnosed correctly, but the diagnosis is irrelevant. A correct diagnosis may be irrelevant because treatment for the disease is not available, not needed, or not wanted. Four drivers engender overdiagnosis: 1) screening in non symptomatic subjects; 2) raised sensitivity of diagnostic tests; 3) incidental overdiagnosis; 4) broadening of diagnostic criteria for diseases. "Defensive medicine" can play a role. It begs the question of whether even in the context of Occupational Medicine overdiagnosis is possible. In relation to the double diagnostic evaluation peculiar to Occupational Medicine, the clinical and the causal, a dual phenomenon is possible: that of overdiagnosis properly said and what we could define the overattribution, in relation to the assessment of a causal relationship with work. Examples of occupational "diseases" that can represent cases of overdiagnosis, with the possible consequences of overtreatment, consisting of unnecessary and socially harmful limitations to fitness for work, are taken into consideration: pleural plaques, alterations of the intervertebral discs, "small airways disease", sub-clinical hearing impairment. In Italy the National Insurance for occupational diseases (INAIL) regularly recognizes less than 50% of the notified diseases; this might suggest overdiagnosis and possibly overattribution in reporting. Physicians dealing with the diagnosis of occupational diseases are obviously requested to perform a careful, up-to-date and active investigation. When applying to the diagnosis of occupational diseases, proper
Beer, A M; Schilcher, H; Loew, D
Herbal pharmaceuticals in medical practice are similarly used as chemically well defined drugs. Like other synthetical drugs, they are subject to pharmaceutical legislature (AMG) and EU directives. It is to differentiate between phytopharmaceuticals with effectiveness of proven indications and traditional registered herbal medicine. Through the Health Reform Act January 2004 and the policy of the Common Federal Committee (G-BA)on the contractual medical care from March 2009--with four exceptions--Non-prescription Phytopharmaka of the legal Health insurance is no longer (SHI) refundable and must be paid by the patients. The result is that more and more well-established preparations disappear from the market. This article gives an overview of practical relevant indications for herbal medicines, which according to its licensing status, the scientific assessment by the Cochrane Collaboration and the Institute for Quality and Efficiency in Health Care (IQWiG) and evidence-based Medicine (EBM)/ meta-analyzes as an alternative to synthetics can be used. PMID:24934061
... Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products For Consumers Home For Consumers Consumer Information by Audience For Women Medicine and Pregnancy Share Tweet Linkedin Pin it ...
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This thesis is concerns research on monoterpenoids, sesquiterpenoids, and diterpenoids with medicinal properties. Terpenoids from commond herbs as well as Cannabis sativa, Inula britannica, Tanacetum parthenium, and Salvia officinalis were investigated
Full Text Available ... variety of diseases, including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities ... and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically ...
Full Text Available ... take medicine safely, people can vastly lower the quality of their lives and in some extreme cases, ... the other one standing on my head, you know, it really gets to be difficult. Announcer: Some ...
Full Text Available Announcer: Recent studies show that nearly 2/3 of all visits to the doctor's office end with a prescription for medication. There is approximately $75 billion spent annually on prescription medicine. ...
Full Text Available ... annually on prescription medicine. All too often, however, we overlook the vital role medication plays in our ... have switched to the non-prescription status so we have a lot of potent medications available for ...
Greenbaum, Dorian Gieseler
Astronomy and astrology were combined with medicine for thousands of years. Beginning in Mesopotamia in the second millennium BCE and continuing into the eighteenth century, medical practitioners used astronomy/astrology as an important part of diagnosis and prescription. Throughout this time frame, scientists cited the similarities between medicine and astrology, in addition to combining the two in practice. Hippocrates and Galen based medical theories on the relationship between heavenly bodies and human bodies. In an enduring cultural phenomenon, parts of the body as well as diseases were linked to zodiac signs and planets. In Renaissance universities, astronomy and astrology were studied by students of medicine. History records a long tradition of astrologer-physicians. This chapter covers the topic of astronomy, astrology, and medicine from the Old Babylonian period to the Enlightenment.
Full Text Available ... after leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer in your child’s body will lose its radioactivity over time. In many cases, the radioactivity will ...
Full Text Available ... nuclear medicine imaging uses small amounts of radioactive materials called radiotracers, a special camera and a computer ... medical imaging that uses small amounts of radioactive material to diagnose and determine the severity of or ...
Full Text Available ... teeth or eating breakfast. By communicating with our health care providers and by accepting a greater responsibility in our own health care, we can learn to take our medicines safely.
Full Text Available ... that nearly 2/3 of all visits to the doctor's office end with a prescription for medication. ... prescription medicine. All too often, however, we overlook the vital role medication plays in our lives. It's ...
Full Text Available ... Videos related to Children's (Pediatric) Nuclear Medicine About this Site RadiologyInfo.org is produced by: Please note ... you can search the ACR-accredited facilities database . This website does not provide cost information. The costs ...
Full Text Available ... not experience any discomfort. When swallowed, the radiotracer has little or no taste. If inhaled, your child ... after the nuclear medicine scan. If the child has been sedated, you will receive specific instructions to ...
Tarver, William J.
Learning Objectives are: (1) Understand the unique work environment of astronauts. (2) Understand the effect microgravity has on human physiology (3) Understand how NASA Space Medicine Division is mitigating the health risks of space missions.
Full Text Available ... nearly 2/3 of all visits to the doctor's office end with a prescription for medication. There ... counter remedies. Prescription medicine is prescribed by a doctor for a specific ailment, using his or her ...
Full Text Available ... the bacteria, but it might not completely give what they call a "bactericidal effect." That means taking ... be sure to ask the following six questions-- What is the name of the medicine? What is ...
... in your carry-on luggage. To help with security at the airport: Keep medicine in the original ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...
Full Text Available ... top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations ... diagnosis or to determine appropriate treatment, if any. Risks Because the doses of radiotracer administered are small, ...
Full Text Available ... understand the difference between prescription and over-the-counter remedies. Prescription medicine is prescribed by a doctor ... or her medical knowledge and expertise. Over-the-counter remedies can be purchased by any person, without ...
The article compares homeopathic medicine and primitive magic. The author realises formal similarities beetwen these two fields of knowledge. The primitive homeopathic magic characterised by J. G. Frazer in his The Golden Bought announces that "similar courses similar". M. Mauss and H. Hubert added to this "low" an another formula: "similar acts on similar that courses a contrary phenomenon". The last formula is an identic one with the "low" of homeopathic medicine. Moreover there is a similarity between pantheistic religion of Hahnemann and magician beliefs in the power named mana in Melanesia and Polinesia or orenda, wakan, manitou and so on, by the Indians from The North America. The amazing thing is that homeopathic chemists belive that kinetic power transforms itself into esoteric one, during preparation of homeopathic medicines.In the end of this article the author ascertains that homeopathic medicine and magic has certain paradigm in common what is opposit to racionalism of official European paradigm of thinking. PMID:19244731
Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... the possible charges you will incur. Web page review process: This Web page is reviewed regularly by ...
Full Text Available ... I take it and for how long? What foods, drinks, other medicines or activities should I avoid ... twice a day and one of them with food and the other one standing on my head, ...
Full Text Available Nanotechnology is an exciting new area in science, with many possible applications in medicine. This article seeks to outline the role of different areas such as diagnosis of diseases, drug delivery, imaging, and so on.
Full Text Available ... medicine will interpret the images and forward a report to your referring physician. top of page What ... by: Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical ...
Full Text Available ... if they occur? And, is there any written information available about the medicine? There are many reasons ... seven days of the week. Announcer: Regardless of age or economic status, taking medication can be as ...
Full Text Available Abstract This editorial is to announce the Journal of Occupational Medicine and Toxicology, a new Open Access, peer-reviewed, online journal published by BioMed Central. Occupational medicine and toxicology belong to the most wide ranging disciplines of all medical specialties. The field is devoted to the diagnosis, prevention, management and scientific analysis of diseases from the fields of occupational and environmental medicine and toxicology. It also covers the promotion of occupational and environmental health. The complexity of modern industrial processes has dramatically changed over the past years and today's areas include effects of atmospheric pollution, carcinogenesis, biological monitoring, ergonomics, epidemiology, product safety and health promotion. We hope that the launch of the Journal of Occupational Medicine and Toxicology will aid in the advance of these important areas of research bringing together multi-disciplinary research findings.
Pedersen, Bente Klarlund; Saltin, Bengt
This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis...
Cellek, Selim; Giraldi, Annamaria
The sexual medicine field has been in mode of revolution until recently. Like all other fields of biomedical research, the economic situation around the world has had a negative impact on the field's momentum-research funding bodies, regulatory bodies and pharmaceutical companies seem to have...... placed sexual medicine in their low-priority list. But this is not the only challenge the field is facing. The successful development of phosphodiesterase type 5 (PDE5) inhibitors for treatment of erectile dysfunction (ED) means that research in this area seems to have slowed. However, there remain...... several unmet medical needs within sexual medicine such as premature ejaculation, severe ED and hypoactive sexual desire disorder, which await novel therapeutic approaches. Despite these challenges, research into finding and developing such therapies is likely to continue in the sexual medicine field...
Full Text Available ... all visits to the doctor's office end with a prescription for medication. There is approximately $75 billion ... the-counter remedies. Prescription medicine is prescribed by a doctor for a specific ailment, using his or ...
Full Text Available ... in the United States, most of us, our culture, is that we take antibiotics for seven to ... I take it and for how long? What foods, drinks, other medicines or activities should I avoid ...
Full Text Available ... after the procedure? Except for intravenous injections, most nuclear medicine procedures are painless and are rarely associated with significant discomfort or side effects. If the radiotracer is given intravenously, your child ...
Full Text Available ... or eating breakfast. By communicating with our health care providers and by accepting a greater responsibility in our own health care, we can learn to take our medicines safely.
The article discusses the uses of marine organisms in folk medicine and in horticulture in the Philippines. Commonly used marine organisms are the different varieties of seaweeds, sea urchin, sea cucumber, turtle, crocodile and fishes such as grouper and rabbitfish.
... with other active ingredients, such as decongestants or antihistamines. Drug Recall Information View information on recent drug ... in nursing babies. Limit long-term use of antihistamines. Just like other medicines you take, antihistamines will ...
Full Text Available ... means taking the bacteria completely out of the system. It might be just putting it to rest ... if they occur? And, is there any written information available about the medicine? There are many reasons ...
... go bad before the expiration date. Pills and capsules are easily damaged by heat and moisture. Aspirin ... medicine with something that ruins it, such as coffee grounds or kitty litter. Put the entire mixture ...
Full Text Available ... leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer ... possible charges you will incur. Web page review process: This Web page is reviewed regularly by a ...
The importance of nuclear methods within today's medicine derives decisively from the field of diagnostics. Among the clinical treatment possibilities on the whole, therapy with unsealed radioactive sources is for the time being restricted to few diseases. The use of radioactive labeling in biology, biochemistry and, especially, pharmacology and the rest of fundamental medical research does not belong to the actual specialty of nuclear medicine. Nuclear in-vitro diagnostics, which currently account for about two thirds of all activities in nuclear medicine, are largely excluded from this survey, which is mainly restricted to nuclear diagnostics in vivo. This presentation of nuclear diagnostics in vivo is addressed above all to non-specialists who are to be made familiar with the modern methods of clinical nuclear medicine so that these investigation methods could be more effectively used in future both with qualitative and quantitative regards. (orig./MG)
Full Text Available ... teeth or eating breakfast. By communicating with our health care providers and by accepting a greater responsibility in our own health care, we can learn to take our medicines ...
Stewart, Lowan H; Trunkey, Donald; Rebagliati, G Steve
Recent events, including the development of space tourism and commercial spaceflight, have increased the need for specialists in space medicine. With increased duration of missions and distance from Earth, medical and surgical events will become inevitable. Ground-based medical support will no longer be adequate when return to Earth is not an option. Pending the inclusion of sub-specialists, clinical skills and medical expertise will be required that go beyond those of current physician-astronauts, yet are well within the scope of Emergency Medicine. Emergency physicians have the necessary broad knowledge base as well as proficiency in basic surgical skills and management of the critically ill and injured. Space medicine shares many attributes with extreme conditions and environments that many emergency physicians already specialize in. This article is an introduction to space medicine, and a review of current issues in the emergent management of medical and surgical disease during spaceflight. PMID:17239732
Full Text Available ... nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce ... manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/ ...
Complementary medicine (CM), defined as health care which lies for the most part outside the mainstream of conventional medicine, is gaining popularity in Britain and elsewhere. In the UK the most prevalent therapies are manipulation (used by 36% of the population), herbalism (24%) homoeopathy (16%) and acupuncture (16%). Due to the heterogeneity of CM, it is often problematic to generalize. The debate about the usefulness of CM is often regrettably emotional, and thus unproductive. In the pu...
Edwards, G. P. L.
Medicine selection and storage was examined in 130 families. Over 50 per cent were found to be less than adequate. Health education advice helped half the inadequate group to change to adequate. Age and social class were not related to hoarding of prescribed drugs, to initial standards of storage or selection, nor to the likelihood of a response to advice. Those who hoarded medicines but stored them well were highly likely to change. Those who stored and selected poorly were unlikely to make ...
This book deals with the medicine of water handling, which includes medicine for dispersion and cohesion, zeta-potential, congelation with Shalze Hardy's law, inorganic coagulants, inorganic high molecule coagulants, aid coagulant such as fly ash and sodium hydroxide, and effect of aluminum and iron on cohesion of clay suspension, organic coagulants like history of organic coagulants, a polyelectrolyte, coagulants for cation, and organic polymer coagulant, heavy metal and cyan exfoliants, application of drugs of water treatment.
The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)
Kuznetsov, D. N.; Syryamkin, V. I.
Modern technologies play a very important role in our lives. It is hard to imagine how people can get along without personal computers, and companies - without powerful computer centers. Nowadays, many devices make modern medicine more effective. Medicine is developing constantly, so introduction of robots in this sector is a very promising activity. Advances in technology have influenced medicine greatly. Robotic surgery is now actively developing worldwide. Scientists have been carrying out research and practical attempts to create robotic surgeons for more than 20 years, since the mid-80s of the last century. Robotic assistants play an important role in modern medicine. This industry is new enough and is at the early stage of development; despite this, some developments already have worldwide application; they function successfully and bring invaluable help to employees of medical institutions. Today, doctors can perform operations that seemed impossible a few years ago. Such progress in medicine is due to many factors. First, modern operating rooms are equipped with up-to-date equipment, allowing doctors to make operations more accurately and with less risk to the patient. Second, technology has enabled to improve the quality of doctors' training. Various types of robots exist now: assistants, military robots, space, household and medical, of course. Further, we should make a detailed analysis of existing types of robots and their application. The purpose of the article is to illustrate the most popular types of robots used in medicine.
Full Text Available "nThere are two mutually supportive systems in medical profession: modern medicines and traditional medicine. The current status is that although the modern medicine occupies the major position in healthcare system, the therapeutic effect of traditional medicines should not be omitted. If all of them merged and unified as one, it will be beneficial to the development of human medicine. In this paper, the integration of Traditional Chinese Medicine (TCM and modern medicine was exemplified to elucidate the mutual complements, mutual benefits of traditional medicines and modern medicine to maintain the unification of human medicine via the development of molecular biology, cytology etc. We believed that TCM theory may share the same mechanism with western medicine at some extent which need to be explored in the future research. In our point of view, although the road may twist and turn, the results are promising.
Traditional Chinese medicine is one of the component parts of the international health care system. It has been an inevitable trend to merge traditional Chinese medicine into systemic medicine. Along with the emergence of the concept of systemic disease, the wide dissemination of evidence-based medicine and the establishment of thought pattern of systemic medicine, the exploration emphasis of modern medical science has been transferred from microcosmic or solid structure to macrocosmic unit a...
Patel, Aarti; Gauld, Robin; Norris, Pauline;
Generic Medicines are an important policy option allowing for access to affordable, essential medicines. Quality of generic medicines must be guaranteed through the activities of national medicines regulatory authorities. Existing negative perceptions surrounding the quality of generic medicines ...
... Alternative Medicine (CAM) Go Back Complementary and Alternative Medicine (CAM) Email Print + Share Crohn’s disease and ulcerative ... Energy Medicine, and Biologically-Based Practices. Mind-Body Medicine Mind-body medicine is a set of interventions ...
Over the past decade many IAEA programmes have significantly enhanced the capabilities of numerous Member States in the field of nuclear medicine. Functional imaging using nuclear medicine procedures has become an indispensable tool for the diagnosis, treatment planning and management of patients. However, due to the heterogeneous growth and development of nuclear medicine in the IAEA's Member States, the operating standards of practice vary considerably from country to country and region to region. This publication is the result of the work of over 30 international professionals who have assisted the IAEA in the process of standardization and harmonization. This manual sets out the prerequisites for the establishment of a nuclear medicine service, including basic infrastructure, suitable premises, reliable supply of electricity, maintenance of a steady temperature, dust exclusion for gamma cameras and radiopharmacy dispensaries. It offers clear guidance on human resources and training needs for medical doctors, technologists, radiopharmaceutical scientists, physicists and specialist nurses in the practice of nuclear medicine. The manual describes the requirements for safe preparation and quality control of radiopharmaceuticals. In addition, it contains essential requirements for maintenance of facilities and instruments, for radiation hygiene and for optimization of nuclear medicine operational performance with the use of working clinical protocols. The result is a comprehensive guide at an international level that contains practical suggestions based on the experience of professionals around the globe. This publication will be of interest to nuclear medicine physicians, radiologists, medical educationalists, diagnostic centre managers, medical physicists, medical technologists, radiopharmacists, specialist nurses, clinical scientists and those engaged in quality assurance and control systems in public health in both developed and developing countries
Mostafa Nemati Paykani; Nastaran Jalilian
In order to collect and determine medicinal plants of Kermanshah province, at first a list of medicinal plants and their localities was prepared based on the floristic list of the Kermanshah province mentioned as medicinal plants in the related references. Then, stands of the mentioned medicinal plants were referred according to the topographic maps and the extracted localities and after collecting medicinal plant specimens, herbarium specimens were prepared based on the traditional taxonomic...
The last developments in medical imaging allow visualization of medicines in organism. Today, these techniques: positron emission tomography (PET) and single photon emission computed tomography (SPECT) play an essential role in the production and the development of new medicines. The medicinal substances labelled with radioisotopes permit to improve the understanding of medicines' action mode. The spectacular advances were observed in the field of medicines acting on the brain (F.M.)
Full Text Available Gymnema sylvestre (Asclepiadaceae, popularly known as “gurmar” for its distinct property as sugar destroyer, is a reputed herb in the Ayurvedic system of medicine. The phytoconstituents responsible for sweet suppression activity includes triterpene saponins known as gymnemic acids, gymnemasaponins, and a polypeptide, gurmarin. The herb exhibits a broad range of therapeutic effects as an effective natural remedy for diabetes, besides being used for arthritis, diuretic, anemia, osteoporosis, hypercholesterolemia, cardiopathy, asthma, constipation, microbial infections, indigestion, and anti-inflammatory. G. sylvestre has good prospects in the treatment of diabetes as it shows positive effects on blood sugar homeostasis, controls sugar cravings, and promotes regeneration of pancreas. The herbal extract is used in dietary supplements since it reduces body weight, blood cholesterol, and triglyceride levels and holds great prospects in dietary as well as pharmacological applications. This review explores the transition of a traditional therapeutic to a modern contemporary medication with an overview of phytochemistry and pharmacological activities of the herb and its phytoconstituents.
Full Text Available Bioaccumulation of Mercury and Cadmium in Bacopa monnieri (L. Pennell, cultivated in Hoagland medium artificially contaminated with micro quantities of HgCl2 and CdCl2 is investigated. Bioaccumulation potential of B. monnieri is more towards Cd than Hg. Absorption and translocation of Hg and Cd are proportional to the availability of the metal in the growth media and period of growth. Effect of acidic pH showed enhanced accumulation while basic pH resulted in significant reduction in the accumulation of Hg and exorbitant reduction of Cd. As a result of combined treatment of HgCl2 and CdCl2, accumulation was very low in both acidic and basic pH. In addition to pH, antagonistic effect of Ca2+ present in lime water which was added to raise the pH of the growth medium also controls the accumulation and absorption of Hg and Cd ions. Bioaccumulation of Hg and Cd in B. monnieri reveals the phytoremediation potential while the bioaccumulation is hazards to health since the plant is highly medicinal and one important ingredient of many Ayurvedic preparations.
Rivlin, Richard S
Garlic has been used medicinally since antiquity. In virtually every early civilization known, such as ancient India, Egypt, Rome, China, and Japan, garlic was part of the therapeutic regimen for a variety of maladies. Therefore, the ancient medicinal tradition of garlic use would qualify it as a folk medicine or as an alternative or complementary medicine. But is garlic an alternative to established methods of disease prevention or treatment? Scientists from around the world have identified a number of bioactive substances in garlic that are water soluble (e.g., S-allyl methylcysteine), and fat soluble (e.g., diallyldisulfide). Mechanisms of action are being elucidated by modern technology. The validity of ancient medicine is now being evaluated critically in cell-free systems, animal models, and human populations. Preventive and therapeutic trials of garlic are still in early stages. There are many promising lines of research suggesting the potential effects of garlic. The current state of knowledge does not recognize garlic as a true alternative, but it will likely find a place for garlic as a complement to established methods of disease prevention and treatment. Our goal should be to examine garlic together with other agents to evaluate its possible efficacy and toxicity under conditions of actual use in humans. PMID:16484549
Historians of Chinese medicine acknowledge the plurality of Chinese medicine along both synchronic and diachronic dimensions. Yet, there remains a tendency to think of tradition as being defined by some unchanging features. The Chinese medical body is a case in point. This is assumed to have been formalised by the late Han dynasty around a system of internal organs, conduits, collaterals, and associated body structures. Although criticism was voiced from time to time, this body and the micro/macrocosmic cosmological resonances that underpin it are seen to persist until the present day. I challenge this view by attending to attempts by physicians in China and Japan in the period from the mid 16th to the late 18th century to reimagine this body. Working within the domain of cold damage therapeutics and combining philological scholarship, empirical observations, and new hermeneutic strategies these physicians worked their way towards a new territorial understanding of the body and of medicine as warfare that required an intimate familiarity with the body’s topography. In late imperial China this new view of the body and medicine was gradually re-absorbed into the mainstream. In Japan, however, it led to a break with this orthodoxy that in the Republican era became influential in China once more. I argue that attending further to the innovations of this period from a transnational perspective - commonly portrayed as one of decline - may help to go beyond the modern insistence to frame East Asian medicines as traditional. PMID:26869864
This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base
Satyanarayanajois, Seetharama D; Hill, Ronald A
Rapid advances in our collective understanding of biomolecular structure and, in concert, of biochemical systems, coupled with developments in computational methods, have massively impacted the field of medicinal chemistry over the past two decades, with even greater changes appearing on the horizon. In this perspective, we endeavor to profile some of the most prominent determinants of change and speculate as to further evolution that may consequently occur during the next decade. The five main angles to be addressed are: protein-protein interactions; peptides and peptidomimetics; molecular diversity and pharmacological space; molecular pharmacodynamics (significance, potential and challenges); and early-stage clinical efficacy and safety. We then consider, in light of these, the future of medicinal chemistry and the educational preparation that will be required for future medicinal chemists. PMID:22004084
The purpose of this Workshop was to discuss and promote future nuclear medicine applications. Atomic Energy of Canada Limited (AECL) is determined to assist in this role. A major aim of this gathering was to form an interface that was meaningful, representative of the two entities, and above all, on-going. In the opening address, given by Mr. J. Donnelly, President of AECL, this strong commitment was emphasized. In the individual sessions, AECL participants outlined R and D programs and unique expertise that promised to be of interest to members of the nuclear medicine community. The latter group, in turn, described what they saw as some problems and needs of nuclear medicine, especially in the near future. These Proceedings comprise the record of the formal presentations. Additionally, a system of reporting by rapporteurs insured a summary of informal discussions at the sessions and brought to focus pertinent conclusions of the workshop attendees
This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base.
Hølge-Hazelton, Bibi; Malterud, Kirsti
are regarded as normal to the extent that female values disappear or need to be blatantly highlighted in order to be recognized. We have applied this frame of reference to understand how the idea of gender neutrality has been established in medicine. The average medical practitioner, teacher, or researcher...... is a man. We suggest that notions of normality subtly construct gender in medicine in ways where men become normal, while women become deviant. Finally, we discuss strengths and pitfalls of three different strategies which have been used by gender researchers in health to challenge andronormativity......: demonstrating gender differences, revealing the consequences of gendered power inequalities, and deconstructing the meaning of gender. Conclusions: We conclude that gender still matters in medicine....
This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area. Engineering in Translational Medicine gives readers a comprehensive and in-depth overview of a broad array of related research areas, making this an excellent reference book for scientists and students both new to engineering/translational medicine and currently working in this area.
Thorsen, Rikke Stamp
People use traditional medicine to meet their health care needs in developing countries and medical pluralism persists worldwide despite increased access to allopathic medicine. Traditional medicine includes a variety of treatment opportunities, among others, consultation with a traditional healer...... or spiritual healer and self-treatment with herbal medicine or medicinal plants. Reliance on traditional medicine varies between countries and rural and urban areas, but is reported to be as high as 80% in some developing countries. Increased realization of the continued importance of traditional medicine has...... led to the formulation of policies on the integration of traditional medicine into public health care. Local level integration is already taking place as people use multiple treatments when experiencing illness. Research on local level use of traditional medicine for health care, in particular the use...
Nuclear medicine can synergistically contribute to the sports medicine field, in the management of sports-related stress injures. Bone scintigraphy is commonly requested for evaluation of athletes with pain. Three-Phase 99mTc MDP Bone Scan has emerged as the imaging reference standard for diagnosing such injuries. The inherently high-contrast resolution of the bone scan allows early detection of bone trauma and becomes positive within six to seventy-two hours after the onset of symptoms. The bone scan is able to demonstrate stress injuries days to weeks before the radiograph
Trepanation and craniotomy are two of the oldest surgical procedures known, and extensive archaeological evidence of trepanation exists in ancient cultures. However, the first descriptions of the surgical techniques are from Greek and Roman medicine, where cranial surgery was used to treat head trauma. This article concerns neurosurgery in ancient medicine, with an emphasis on "De Medicina" by Aulus Cornelius Celsus (25 BC-50 AD) and the Corpus Hippocraticum (about 400 BC). These texts are further considered in the light of excavated surgical instruments from Pompeii. PMID:16357902
Bastardot, F; Vollenweider, P; Marques-Vidal, P
Social networks (social media or #SoMe) have entered medical practice within the last few years. These new media--like Twitter or Skype--enrich interactions among physicians (telemedicine), among physicians and patients (virtual consultations) and change the way of teaching medicine. They also entail new ethical, deontological and legal issues: the extension of the consultation area beyond the medical office and the access of information by third parties were recently debated. We develop here a review of some social networks with their characteristics, applications for medicine and limitations, and we offer some recommendations of good practice. PMID:26685647
Cherry, Simon R; Phelps, Michael E
Physics in Nuclear Medicine - by Drs. Simon R. Cherry, James A. Sorenson, and Michael E. Phelps - provides current, comprehensive guidance on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. This revised and updated fourth edition features a new full-color layout, as well as the latest information on instrumentation and technology. Stay current on crucial developments in hybrid imaging (PET/CT and SPECT/CT), and small animal imaging, and benefit from the new section on tracer kinetic modeling in neuroreceptor imaging.
Money, Nicholas P
Despite the longstanding use of dried mushrooms and mushroom extracts in traditional Chinese medicine, there is no scientific evidence to support the effectiveness of these preparations in the treatment of human disease. Consumers should evaluate assertions made by companies about the miraculous properties of medicinal mushrooms very critically. The potential harm caused by these natural products is another important consideration. In a more positive vein, the presence of potent toxins and neurotropic compounds in basidiomycete fruit bodies suggests that secondary metabolites with useful pharmacological properties are widespread in these fungi. Major investment in controlled experiments and objective clinical trials is necessary to develop this natural pharmacopeia. PMID:27020147
Full Text Available The holistic medical approach seems to be efficient and can also be used in adolescent medicine. Supporting the teenager to grow and develop is extremely important in order to prevent many of the problems they can carry into adulthood. The simple consciousness-based, holistic medicine — giving love, winning trust, giving holding, and getting permission to help the patient feel, understand, and let go of negative beliefs — is easy for the physician interested in this kind of practice and it requires little previous training for the physician to be able to care for his/her patient. A deeper insight into the principles of holistic treatment and a thorough understanding of our fellow human beings are making it work even better. Holistic medicine is not a miracle cure, but rather a means by which the empathic physician can support the patient in improving his/her future life in respect to quality of life, health, and functional capacity — through coaching the patient to work on him/herself in a hard and disciplined manner. When the patient is young, this work is so much easier. During our lifetime, we have several emotional traumas arranged in the subconscious mind with the smallest at the top, and it is normal for the person to work on a large number of traumatic events that have been processed to varying degrees. Some traumas have been acknowledged, some are still being explored by the person, and yet others are still preconscious, which can be seen for example in the form of muscle tension. Sometimes the young dysfunctional patient carries severe traumas of a violent or sexual nature, but the physician skilled in the holistic medical toolbox can help the patient on his/her way to an excellent quality of life, full self-expression, a love and sex life, and a realization of his/her talents — all that a young patient is typically dreaming about. Biomedicine is not necessary or even recommended when the physical or mental symptoms are caused
What is a Sports Medicine Specialist? A physician with significant specialized training in both the treatment and prevention of illness and injury. The Sports Medicine Specialist helps patients maximize function and minimize ...
Full Text Available ... and I'm taking one of them four times a day and one of them three times a day and one of them twice a ... January." It's easy to remember-- write down the time you take your medicine and as you take ...
Full Text Available ... like? Special camera or imaging devices used in nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also called a scintillation camera, detects radioactive energy that is emitted from the patient's body and ...
This essay aims to provoke debate on how and what the medical humanities should teach. It argues that the field has been dominated (to its detriment) by two misguided movements, postmodernism and narrative medicine, and that it should be redirected from utilitarian aims towards the goal of exposing medical students to a climate of thought and reflection. PMID:24769751
Lippi, Donatella; Roberti di Sarsina, Paolo; D'Elios, John Patrick
Healing sounds have always been considered in the past an important aid in medical practice, and nowadays, medicine has confirmed the efficacy of music therapy in many diseases. The aim of this study is to assess the curative power of music, in the frame of the current clinical relationship. PMID:21197362
This bulletin contains seven articles relating to the isotopic applications in medicine. Their subject matter ranges from the preparation of radiopharmaceuticals through their application in scintiscanning to computer codes for evaluation of the results. The individual articles have been indexed separately
The family Compositae is one of the largest in the plant kingdom. Several species are used in popular medicin. Thus, the leaf extract of Calea pinnatifida Banks, known as aruca, is employed in the treatment of amoebiasis. A chemical study is carried out in order to discover the active principles of the species. (Author)
This is the first of two articles showing how plants that have been used in folk medicine for many centuries are guiding scientists in the design and preparation of new and potent drugs. Opium and its chemical derivatives are examined at length in this article. (Author/MA)
Pedersen, T.; Gluud, Christian Nyfeldt; Gøtzsche, Peter C.;
of a diagnostic method is a randomised trial. Evidence-based medicine will provide the best basis for evaluations of which interventions should be abandoned and which are effective and economically feasible. The use of evidence-based clinical guidelines will lead to more cost-effective treatments. It...... should be a national strategy that health care should be evidence-based....
Prof. Turksen is a very well known scientist in the stem cell biology field and he is also internationally known for his fundamental studies on claudin-6. In addition to his research activity he is editor for the Stem Cell Biology and Regenerative Medicine series (Humana Press) and editor-in-chief of Stem Cell Reviews and Reports..... PMID:26972720
Diagnosis of human disease has been undergoing steady improvement over the past few centuries. Many ailments that were once considered a single entity have been classified into finer categories on the basis of response to therapy (e.g. type I and type II diabetes), inheritance (e.g. familial and non-familial polyposis coli), histology (e.g. small cell and adenocarcinoma of lung) and most recently transcriptional profiling (e.g. leukaemia, lymphoma). The next dimension in this finer categorization appears to be the typing of the patient rather than the disease i.e. disease X in person of type Y. The problem of personalized medicine is to devise tests which predict the type of individual, especially where the type is correlated with response to therapy. Immunology has been at the forefront of personalized medicine for quite a while, even though the term is not often used in this connection. Blood grouping and cross-matching (for blood transfusion), and anaphylaxis test (for penicillin) are just two examples. In this paper I will argue that immunological tests have an important place in the future of personalized medicine. I will describe methods we developed for personalizing vaccines based on MHC allele frequencies in human populations and methods for predicting peptide binding to class I MHC molecules. In conclusion, I will argue that immunological tests, and consequently immunoinformatics, will play a big role in making personalized medicine a reality. PMID:14712931
Holloway, K.; Dijk, L. van
1. Irrational use of medicines is an extremely serious global problem that is wasteful and harmful. In developing and transitional countries, in primary care less than 40% of patients in the public sector and 30% of patients in the private sector are treated in accordance with standard treatment gui
Full Text Available ... diagnoses. In addition, manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and ... nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also ...
An entire series could be dedicated to the topic of ethics in personalized medicine. Due to the advancements in NGS and genetic testing, personalized medicine is no longer something that will occur in the future, the reality is upon us now. Sequencing an individual's genome can have a substantial impact on the patient's treatment and overall quality of life. However, this can open "Pandora's box" especially if an individual does not want to know the information obtained. In addition, will insurance companies require genetic testing in order to pay for a targeted treatment? If the patient refuses to have the genetic testing, will they have to pay for their treatment out of pocket? In the human interest story presented, the researcher and his team discovered over activity of the FTL3 protein through RNA sequencing which resulted in rapid proliferation of his leukemic cells. He identified a drug marketed for advanced kidney cancer which was a FTL3 inhibitor. However, his insurance company refused to pay for the drug because it was not a known treatment for his condition of ALL. He incurred numerous out of pocket expenses in order to go into remission. Was it unethical for the insurance company to not pay for a treatment that ultimately worked but was not marketed or FDA cleared for his type of leukemia? There are so many questions and concerns when personalized medicine is implemented. Only time will tell the effects next generation sequencing and its role in personalized medicine will have in the future. PMID:25219077
Describes the history, research, teaching strategies, and specialties of the University of California at Davis School of Veterinary Medicine. Documents effects of changing societal attitudes toward wildlife, pets, working animals, and food animals on curriculum, the systems approach to disease, comparative genetics, biotechnology, the ecology of…
Qattan, Malak; Demonacos, Constantinos; Krstic-Demonacos, Marija
Standard clinical protocols and the concept "one drug fits all" that are currently used to treat illness in many cases are not effective, and strikingly so in the treatment of cancer, where 75% of therapeutic schemes are ineffective. The concept of personalized medicine is that the treatment of the disease is designed on the basis of the individual needs of each patient and the factors that influence their response to different drugs. Individualization of patient care has the potential to generate novel effective therapies, limit the adverse drug effects, create optimal treatments for individual patients, and decrease the cost associated with chronic illness and complications of drug usage. However, to achieve the goals of personalized medicine many challenges must be addressed. Here we discuss possible ways to increase the consistency of data generated by basic research and their suitability for application in medicine. New technologies employing systems biology and computer based approaches will facilitate overcoming many of the scientific challenges in the field. Changes in the education of researchers, health professionals, and the public are also required to successfully implement personalized medicine as a routine in the clinic. Finally, shift of the focus away from the development of blockbuster drugs in the biopharmaceutical industry, and modifications in the legal system to accommodate novel advancements need to be considered. The joint effort of all interested parties is needed to generate an efficient roadmap that will take us rapidly and safely to effective individual treatment, which will eliminate diseases and create better health care for all. PMID:22911518
Created in 1552 as a gift for Spain's king, the Badianus Manuscript is a repository of Aztec traditional medicinal knowledge and contains the earliest surviving illustrations of New World plants. At the College of Santa Cruz (Mexico City) for Aztec nobility, an Aztec healer who became the college physician compiled plant descriptions and medicinal…
Full Text Available The regular supply of radiopharmaceuticals and radioimmunoassay kits from BARC has been an important factor in the development of nuclear medicine in India. However, a major stumbling block has been the non-availability of suitable instrumentation systems (especially the computer-assisted gamma camera at an affordable price. Two recent developments, viz., the creation of the Board of Radioisotope Technology by the Department of Atomic Energy, and the efforts of Electronic Corporation of India Ltd. to design indigenously a gamma camera with a computer attachment, hold promise for the future healthy and rapid growth of nuclear medicine in the country. Training in nuclear medicine at the post-graduate level is gradually picking up. Nuclear medicine is essentially applied physiology and biochemistry, and provides an orientation, different from those of the anatomist and physiologist. The gamma camera, SPECT and PET enable the study of dynamic metabolic function resolution to spatial and temporal resolutions. Newer developments in tagged monoclonal antibodies hold promise for a better understanding of infectious and inflammatory disease which are a burden in the developing countries.
Full Text Available ... pictures and provides molecular information. In many centers, nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce special views, a practice known as image fusion or co-registration. These views allow the information ...
Weber, Holly A., Ed.
The six issues of Wilderness Medicine Newsletter published in 1999 provide medical and rescue information for the nonphysician in remote wilderness areas. Feature articles include: "Tendinitis: Overdoing a Good Thing" (Buck Tilton); "A Sport for the Season: Trail Running" (injuries and health problems common to trail runners) (Rebecca S. Newton);…
Andel, Van Tinde; Onselen, Van Sabine; Myren, Britt; Towns, Alexandra; Quiroz, Diana
Ethnopharmacological relevance Purgative enemas form an integral part of African traditional medicine. Besides possible benefits, serious health risks of rectal herbal therapy have been described in literature. To design appropriate health education programs, it is essential to understand traditi
The cannabis plant (Cannabis sativa L.) has a long history as a recreational drug, but also as part of traditional medicine in many cultures. Nowadays, it is used by a large number of patients worldwide, to ameliorate the symptoms of diseases varying from cancer and AIDS to multiple sclerosis and mi
Technology, which is older than science, has been of vital importance in the development of modern medicine. Even so, there are voices of dissent to be heard. The disenchantment with technology expressed by Aldous Huxley in Brave new world has been echoed by contemporary writers on the technology of modern medicine. Medicine is seen by some to have been dehumanized by technology, and techniques that are expensive are thought to be consuming a greater proportion of health resources than they deserve. The practice of medicine has, nevertheless, been transformed by modern technology and diagnostic techniques and therapeutic measures undreamed of a few short decades ago are now commonplace. There is no reason why these developments should be any more dehumanizing than the use of similar techniques in modern transportation or communication, nor is their expense out of proportion when compared with other demands on the nation's purse. British workers have been at the forefront of many recent advances. Yet, even though the National Health Service provides a ready market for the products of British medical technology, the nation depends to an inordinate degree on imported products. In the development of appropriate medical technology there is an urgent need for better communication between inventors, scientists, industrialists and the National Health Service. At the same time there is an equal need for improved evaluation of untried techniques. The pressure for a central integrating body to coordinate resources could well be supported by the establishment of evaluation units in the different health authorities in this country. PMID:2862631
Sommerkamp, Yvonne; Paz, Ana Margarita; Guzmán, Gastón
Guatemala, located in Central America, has a long and rich history in the traditional use of edible, medicinal, and hallucinogenic mushrooms. This article describes the use of these mushrooms and presents studies on the scientific validation of native and foreign species. PMID:27279440
Prof. Turksen is a very well known scientist in the stem cell biology field and he is also internationally known for his fundamental studies on claudin-6. In addition to his research activity he is editor for the Stem Cell Biology and Regenerative Medicine series (Humana Press) and editor-in-chief of Stem Cell Reviews and Reports.....
Full Text Available Prof. Turksen is a very well known scientist in the stem cell biology field and he is also internationally known for his fundamental studies on claudin-6. In addition to his research activity he is editor for the Stem Cell Biology and Regenerative Medicine series (Humana Press and editor-in-chief of Stem Cell Reviews and Reports.....
Wu, Linping; Ficker, Mario; Christensen, Jørn Bolstad;
Dendrimers are three-dimensional macromolecular structures originating from a central core molecule and surrounded by successive addition of branching layers (generation). These structures exhibit a high degree of molecular uniformity, narrow molecular weight distribution, tunable size and shape ...... as challenging issues surrounding the future development of dendrimer-based medicines....
Hogue, Rebecca J.
This paper discusses the scholarly literature related to tablet computer use in medicine. Forty-four research-based articles were examined for emerging categories and themes. The most studied uses for tablet computers include: patients using tablets to complete diagnostic survey instruments, medical professionals using tablet computers to view…
Salazar-Holguín, H D
Within a conceptualization concerning the health-disease process as a whole (which systematically correlates its biological, psychological, social and historical aspects), it becomes very difficult to find something in the universe involving humankind, without any direct or indirect relationship with that vital process. This fact had expanded medicine toward a very extensive and complex field of knowledge and practices. Just considering it from the scientific perspective, different and opposing acquaintances and research methods vie with each other, equally claiming their own worth and stature within science. Because of all this and from its origin, allopathic medicine has required the assistance and support of philosophy and, in particular, from one specific branch: epidemiology. Nevertheless, since Bacon's empiricism (17th century) and, above all, since Comte's positivism (19th century), there had predominated until now (Piaget) a scientific current which was the enemy of philosophical thinking. In spite of the fact that it constituted, in itself, an epistemological position, being generalized also among biomedical scientists, there is in medicine at least disdain against the philosophy of science. Nevertheless, it is objectively indispensable. So, the present essay is presented in this sense, through the analytic characterization of the prototypic epistemologies and their relationships with medicine throughout history. PMID:9618998
Since China first applied isotopes to medical research in 1956, over 800 hospitals and research institutions with 4000 staff have taken up nuclear technology. So far, over 120 important biologically active materials have been measured by radioimmunoassay in China, and 44 types of RIA kit have been supplied commercially. More than 50,000 cases of hyperthyroidism have been treated satisfactorily with 131I. Radionuclide imaging of practically all organs and systems of the human body has been performed, and adrenal imaging and nuclear cardiology have become routine clinical practice in several large hospitals. The thyroid iodine uptake test, renogram tracing and cardiac function studies with a cardiac probe are also commonly used in most Chinese hospitals. The active principles of more than 60 medicinal herbs have been labelled with isotopes in order to study the drug metabolism and mechanism of action. Through the use of labelled neurotransmitters or deoxyglucose, RIA, radioreceptor assay and autoradiography, Chinese researchers have made remarkable achievements in the study of the scientific basis of acupuncture analgesia. In 1980 the Chinese Society of Nuclear Medicine was founded, and since 1981 the Chinese Journal of Nuclear Medicine has been published. Although nuclear medicine in China has already made some progress, when compared with advanced countries, much progress is still to be made. It is hoped that international scientific exchange will be strengthened in the future. (author)
The essence of the traditional Chinese medicine has always been the most advanced and experienced therapeutic approach in the world. It has knowledge that can impact the direction of future modern medical development; still, it is easy to find simple knowledge with mark of times and special cultures. The basic structure of traditional Chinese medicine is composed of three parts: one consistent with modern medicine, one involuntarily beyond modern medicine, and one that needs to be further eva...
Malentacchi, Francesca; Mancini, Irene; Brandslund, Ivan;
the European Society of Pharmacogenomics and Personalised Therapy (ESPT). The answers of the participating laboratory medicine professionals indicate that they are aware that personalized medicine can represent a new and promising health model, and that laboratory medicine should play a key role in...
Yuan, Haidan; Ma, Qianqian; Ye, Li; Piao, Guangchun
Natural products and traditional medicines are of great importance. Such forms of medicine as traditional Chinese medicine, Ayurveda, Kampo, traditional Korean medicine, and Unani have been practiced in some areas of the world and have blossomed into orderly-regulated systems of medicine. This study aims to review the literature on the relationship among natural products, traditional medicines, and modern medicine, and to explore the possible concepts and methodologies from natural products and traditional medicines to further develop drug discovery. The unique characteristics of theory, application, current role or status, and modern research of eight kinds of traditional medicine systems are summarized in this study. Although only a tiny fraction of the existing plant species have been scientifically researched for bioactivities since 1805, when the first pharmacologically-active compound morphine was isolated from opium, natural products and traditional medicines have already made fruitful contributions for modern medicine. When used to develop new drugs, natural products and traditional medicines have their incomparable advantages, such as abundant clinical experiences, and their unique diversity of chemical structures and biological activities. PMID:27136524
Natural medicines provide valuable resources to meet the requirements for global health care at affordable prices.Therefore, safety and efficacy need to be proven in a comparable manner to conventional drugs. Evidence-based natural and western medicine may merge to a "one-world medicine" for the sake of all patients in industrialized and developing countries. In the present review, we discuss strategies for(1)preservation of traditional knowledge on natural medicines,(2)sustainability of medicinal herbs and natural products, and(3)standardization and quality control. Novel technologies will impact research on natural medicines in the years to come, e.g. remote sensing to map medicinal plant locations, DNA barcoding for plant authentication, hollow fiber extraction,high-end techniques for chemo-profiling of plant constituents in medicinal products and blood serum of patients as well as systems biological approaches.
Over-the-counter (OTC) medicines are drugs you can buy without a prescription. Some OTC medicines relieve aches, pains ... Others help manage recurring problems, like migraines. In the United States, the Food and Drug Administration decides ...
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Benor, Daniel J
Energy medicine includes a broad variety of complementary/ alternative medicine (CAM) therapies, such as acupuncture, kinesiology, and spiritual healing. The term "energy medicine" derives from the perceptions and beliefs of therapists and patients that there are subtle, biological energies that surround and permeate the body. Recent research is confirming that these therapies can be helpful in treating many problems for which conventional medicine may have no cures. Growing numbers of doctor...
Kucinskiene, Zita Ausrele; Bartlingas, Jonas
In Lithuania there are two types of specialists working in medical laboratories and having a university degree: laboratory medicine physicians and medical biologists. Both types of specialists are officially being recognized and regulated by the Ministry of Health of Lithuania. Laboratory medicine physicians become specialists in laboratory medicine after an accredited 4-year multidisciplinary residency study program in Laboratory Medicine. The residency program curriculum for laboratory m...
India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs) are now used for the prevention and...
In Ayurveda many medicinal plants are described and are widely used by traditional practitioners for curing and controlling various diseases. Acorus calamus is one of the important herbs known for its medicinal properties. In the ancient medicine it was mainly used for its effect on central nervous system. It is a perennial, aromatic herb with creeping rhizomes commonly known as sweet flag and contains a wide variety of phytoconstituents having different medicinal properties. Exploring these ...
Sanford, Christopher A; Pottinger, Paul S
Given the ever-changing nature of travel medicine, practitioners who provide pretravel and posttravel care are obligatorily students for the duration of their professional careers. A large variety of resources are available for medical practitioners. Providers should join at least one travel or tropical medicine professional association, attend its annual meeting, and read its journal. The largest general travel medicine association is the International Society of Travel Medicine. PMID:26900122
Nuclear Medicine Technology Study Guide presents a comprehensive review of nuclear medicine principles and concepts necessary for technologists to pass board examinations. The practice questions and content follow the guidelines of the Nuclear Medicine Technology Certification Board (NMTCB) and American Registry of Radiological Technologists (ARRT), allowing test takers to maximize their success in passing the examinations. The book is organized by sections of increasing difficulty, with over 600 multiple-choice questions covering all areas of nuclear medicine, including radiation safety; radi
De Silva R.H.S.K.; Jayawardhane N.D.N.; Narasimha Murthy K.H.H.V.S.S; Tripathi J.S.
Ayurveda is one of the oldest medical systems in the world. Health is a state of equilibrium of Physical, Psychological and Spiritual components. This equilibrium is maintained between internal and external environment which is known as Loka Purusa Samya. Ayurvedic therapeutics uses herbs and minerals extracted from environment to maintain the well being of human being. Universally this unique feature ensured sustainable utilization of both environmental and Ayurvedic principles in providing ...
Full Text Available ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...
... it costs. Ask if they have a drug discount program that can help you pay less for your medicine. Buy your medicine from the pharmacy that gives you the cheapest price. Sign up for patient assistance programs: Most companies that make medicines have programs that help people ...
... it costs. Ask if they have a drug discount program that can help you pay less for your medicine. Buy your medicine from the pharmacy that gives you the cheapest price. Sign up for patient assistance programs: Most companies that make medicines have programs that help people ...
Pilkington, Karen; Rampes, Hagen; Richardson, Janet
Surveys have demonstrated that complementary medicine use for depression is widespread, although patterns of use vary. A series of systematic reviews provide a summary of the current evidence for acupuncture, aromatherapy and massage, homeopathy, meditation, reflexology, herbal medicine, yoga, and several dietary supplements and relaxation techniques. The quantity and quality of individual studies vary widely, but research interest in complementary therapies is increasing, particularly in herbal and nutritional products. Major questions are still to be answered with respect to the effectiveness and appropriate role of these therapies in the management of depression. Areas for further research and some of the potential challenges to research design are discussed. Finally, several ongoing developments in information provision on this topic are highlighted. PMID:17144787
In nuclear medicine, a sequence of revolutioning research up to the simple and efficient application in routine has always then taken place when in an interdisciplinary teamwork new radiochemical tracers and/or new instrumentation had become available. At present we are at the beginning of a phase that means to be in-vivo-biochemistry, the targets of which are molecular interactions in the form of enzymatic reactions, ligand-receptor interactions or immunological reactions. The possibility to use positron-emitting radionuclides of bioelements in biomolecules or drugs to measure their distribution in the living organism by positron-emission tomography (PET) is gaining admittance into the pretentious themes of main directions of medical research. Diagnostic routine application of biochemically oriented nuclear medicine methods are predominantly expected from the transmission of knowledge in PET research to the larger appliable emission tomography with gamma-emitting tracers (SPECT). (author)
This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.
Williams, Richard S.
The presentation is next Sunday, May 10th. It will be to the Civil Aviation Medical Association, for 2 hours at Disney World in Orlando. It is a high level talk on space medicine, including history, the role of my office, human health risks of space flight, general aspects of space medicine practice, human health risk management (including integrated activities of medical operations and the Human Research Program, and thoughts concerning health risks for long duration exploration class space missions. No proprietary data or material will be used, all is readily available in the public sector. There is also a short (30 min) talk on Monday at the CAMA lunch. There we will describe the Visual Impairment and Intracranial Pressure syndrome, with possible etiologies and plans for research (already selected studies). Again, nothing proprietary will be discussed.
Thibault, George E
More than a decade ago, women achieved parity with men in the number of matriculants to medical school, nearly one-third of the faculty of medical schools were women, and there were some women deans and department chairs. These trends were promising, but today there are still significant differences in pay, academic rank, and leadership positions for women compared with men in academic medicine. Though there has been progress in many areas, the progress is too slow to achieve previously recommended goals, such as 50% women department chairs by 2025 and 50% women deans by 2030.The author points to the findings presented in the articles from the Research Partnership on Women in Biomedical Careers in this issue, as well as research being published elsewhere, as an evidence base for the ongoing discussion of gender equity in academic medicine. More attention to culture and the working environment will be needed to achieve true parity for women in academic medical careers. PMID:27306968
Vano, E.; Holmberg, O.; Perez, M. R.; Ortiz, P.
Diagnostic, interventional and therapeutic used of ionizing radiation are beneficial for hundreds of millions of people each year by improving health care and saving lives. In March 2001, the first International Conference on the Radiological Protection of Patients was held in Malaga, Spain, which led to an international action plan for the radiation protection of patients. Ten years after establishing the international action plan, the International Conference on Radiation Protection in Medicine: Setting the Scene for the Next Decade was held in Bonn, Germany, in December 2012. the main outcome of this conference was the so called Bonn Call for Action that identifies then priority actions to enhance radiation protection in medicine for the next decade. The IAEA and WHO are currently working in close cooperation to foster and support the implementation of these ten priority actions in Member States, but their implementation requires collaboration of national governments, international agencies, researchers, educators, institutions and professional associations. (Author)
Full Text Available A ′need-supply′ and ′requirement-distribution mismatch′ along with a continuingneed explosion are the biggest hurdles faced by palliative medicine today. It is the need of the hour to provide an unbiased, equitable and evidence-based palliative care to those in need irrespective of the diagnosis, prognosis, social and economic status or geographical location. Palliative care as a fundamental human right, ensuring provision throughout the illness spectrum, global as well as region-specific capacity building, uniform availability of essential drugs at an affordable price, a multidisciplinary team approachand caregiver-support are some of the achievable goals for the future. This supplanted with a strong political commitment, professional dedication and ′public-private partnerships′ are necessaryto tackle the existing hurdles and the exponentially increasing future need. For effectively going ahead it is of utmost importance to integrate palliative medicine into medical education, healthcare system and societal framework.
A Symposium with the topic 'Nuclear Medicine and Gastroenterology' was held on the occasion of the annual meeting 1976 of the Rheinisch-Westfalische Gesellschaft fuer Nuklearmedizin, led by Professor Dr.W. Stroetges in the Klinicum of the University of Essen. The meeting report first deals with some well-established examination methods which, however, still need some explanation concerning their diagnostical-patho-physiological background. Then some problems are shown which might be solved with the help of nuclear medicine. 1) Exsudative enteropathy, 2) The problem of the blind loop with bacteria proliferation and its relations to gall acid metabolism, 3) Functional examination of the distal small intestine with absorption of vitamin B12; 4) Some special problems. (orig.)
Four aspect dealts with in this paper are as follows: 1. environment of medicinal plants; 2. brief history on studies of medicinal plants; 3. species of medicinal plants; 4. studies on development and utilization of medicinal plant resources.
Satyanarayanajois, Seetharama D.; Hill, Ronald A
Rapid advances in our collective understanding of biomolecular structure and, in concert, of biochemical systems, coupled with developments in computational methods, have massively impacted the field of medicinal chemistry over the past two decades, with even greater changes appearing on the horizon. In this perspective, we endeavor to profile some of the most prominent determinants of change and speculate as to further evolution that may consequently occur during the next decade. The five ma...
Cederbaum, Stephen D.; Fareed, George C.; Lovett, Michael A.; Shapiro, Larry J.
Studies in bacteria and bacterial viruses have led to methods to manipulate and recombine DNA in unique and reproducible ways and to amplify these recombined molecules millions of times. Once properly identified, the recombinant DNA molecules can be used in various ways useful in medicine and human biology. There are many applications for recombinant DNA technology. Cloned complementary DNA has been used to produce various human proteins in microorganisms. Insulin and growth hormone have been...
This review highlights the importance to people of some types of wild fungi considered in the context of non-wood forest products. Macrofungi are used both for food and medicine proposes. Substances isolated from the higher Basidiomycetes and Ascomycetes mushrooms express promising immune modulating, antitumor, antiviral, antibacterial and antidiabetic properties. They have been, and are presently, used against cancer in some countries in Far East as well as in the United States of America...
Novartis is one of the largest pharmaceutical companies in the world, based in Switzerland, and operating in more than 140 countries worldwide. It is a leading pharmaceutical provider for diseases such as high blood pressure, diabetes, hypertension and cancer, to list a few. Its medicines reach more than 1.1 billion people each year. Our client is Novartis Brazil, a subsidiary operating in a fast growth emerging market.
The purpose of medicine is to serve the community by continually improving health, health care and the quality of life for the individual. Population health is improved by health promotion, prevention of illness, treatment and care and the effective use of resources, all within the context of a team approach. Thus doctors have three broad roles: to provide high quality care, to be concerned with regard to community needs and manage resources effectively.
Eary, Janet F
One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources. Serving as a complete literature reference for therapy with radiopharmaceuticals currently utilized in practice, this source covers the role of the physician in radionuclide therapy, and essential procedures and protocols required by health care personnel.
2009013 Clinical observation on treatment of active rheumatoid arthritis with Chinese herbal medicine. SHENG Zhenghe(盛正和), et al.Dept TCM, 5th Affili Hosp, Guangxi Med Univ, Guangxi 545001. Chin J Integr Tradit West Med 2008;28(11):990-993. Objective To study the efficacy and safety of Chinese drugs for expelling evil-wind, removing dampness, promoting blood circulation and invigorating yin in treating active rheumatoid arthritis (RA).
Zakrzewska, J M
88 members of the UK specialty society of oral medicine were asked about career satisfaction and their views on training programmes. 70% responded (79% of consultants and all accredited trainees). Men work longer hours than women, report less control over their work and experience more stress. Although high work satisfaction is reported, nearly one-third regret their choice of specialty. Men more than women do locum work while training. Most respondents would welcome flexible training, job sh...
Newman, Carlton; Jaggar, David H.
Lasers have been used for some time now on animals for experimental purposes prior to their use in human medical and surgical fields. However the use of lasers in veterinary medicine and surgery per se is a recent development. We describe the application of high and low intensity laser technology in a general overview of the current uses, some limitations to its use and future needs for future inquiry and development.
Shapiro, Simon J.; Stumpf, Steven H.
Unstated and unacknowledged bias has a profound impact on the nature and implementation of integrative education models. Integrative education is the process of training conventional biomedical and traditional Chinese medicine practitioners in each tradition such that patient care may be effectively coordinated. A bilateral education model ensures that students in each tradition are cross-taught by experts from the ‘other’ tradition, imparting knowledge and values in unison. Acculturation is ...
Ridder, Hanne Mette Ochsner
Den første bog, der beskriver bredden inden for området MusikMedicin, starter helt ved begyndelsen, ved ”cellernes sang”, og går derefter videre til at berette om et utal af undersøgelser og teorier om, hvordan musik påvirker både foster og mor, planter og dyr, krop og følelser, immunsystem og...
The number of medical practitioners in the developed world has increased but in relative terms their incomes have decreased. Published comments suggest that some doctors are dissatisfied with what they earn. However doctors are still perceived as having a high status in society. Publicly available data suggests that doctors chose to live and work in affluent suburbs where arguably the need for their skills is less than that in neighbouring deprived areas. The gender balance in medicine is als...
Hélio A.G. Teive
Full Text Available A historical review is presented of the link between Ludwig Wittgenstein, considered the most important philosopher of the 20th century, and medicine, particularly neurology and psychiatry. Wittgenstein worked as a porter at Guy's Hospital in London, and then as a technician at the Royal Victoria Infirmary in Newcastle. He wrote about his important insights into language, and neuroscience. It has been suggested that he had Asperger syndrome and a possible movement disorder (mannerisms.
Fisher, P.; Ward, A.
Complementary or unconventional treatments are used by many doctors and other therapists throughout Europe. The major forms are acupuncture, homoeopathy, manual therapy or manipulation, and phytotherapy or herbal medicine. The relative popularity of therapies differs between countries, but public demand is strong and growing. Regulation of practitioners varies widely: in most countries only registered health professionals may practice, but in the United Kingdom practice is virtually unregulat...
The masterpiece of Marcel Proust contains many important considerations about Medicine. The great french writer knew very well the problems concerning several diseases as he was son and brother of important medical doctors; he also studied the problems concerning the diseases he was affected. He had many important medical intuitions: one of the best was the involuntary memory. In the paper are also described the troubles of a man who suffered all the life until the death. PMID:19569412
Full Text Available Travel broadens the mind" and people have been extolling the merits of travel for a very long time .The general belief is that travel is good for travelers mentally and physically. But while travel can indeed be interesting and exciting, and good for mental and physical wellbeing, all too often it can be harmful to a traveler's health (1 .The increase in numbers of travellers and the speed at which they travel has not only had economic, cultural, and social repercussions, but medical, epidemiological, and medico-legal consequences as well. Travel medicine or Emporiatrics is the branch of medicine that deals with the prevention and management of health problems of international travelers (2. The art of travel medicine is selecting the necessary prevention strategy without unnecessary adverse events, cost or inconvenience" (3. Travel health advice is primarily aimed at prevention, and is therefore offered before travel. It includes steps taken before travel like Medical examinations and screening, Psychological preparation, Provision of a medical kit, First aid training, Preventive measures for prevention of thermal injury, Insure and plan for aeromedical evacuation and repatriation, Advice regarding accidents and related hazards, Special provisions for specific travel hazards and Protection against tropical diseases. There is also an aspect of travel health which is provided after return from travel, which is usually diagnostic (4,5. Giving adequate advice on travel health requires a good knowledge about local health hazards overseas, public health measures, and the effectiveness of immunization and prophylaxis. In summary, travel medicine will be established as an interdisciplinary special discipline in the next years and will be characterized by new risks and on the other hand by new methods of therapy and prophylaxis.
The veterinary use of radionuclide techniques dates back to the mid-sixties, but its more extensive use dates back to the past two decades. Veterinary nuclear medicine is focused mainly on four major issues: bone scintigraphy - with the majority of applications in horses, veterinary endocrinology - dealing mainly with the problems of hyperthyreosis in cats and hyperthyreosis in dogs, portosystemic shunts in small animals and veterinary oncology, however, most radionuclide techniques applied to humans can be applied to most animals. (author)
B.E. Shakhov; E.D. Bozhkova
A development of practical public health in all the times wasn’t possible and full-blooded without a parallel development of medical science. The applied and scientific research constituents of medicine are mutually supplementing ones: the actual questions of clinical picture frequently initiate investigations in the corresponding direction; sometimes the scientific achievements permit to optimize the used methods or create the new ones of diagnosis, treatment and prophylaxis of the different...