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Sample records for avitaminosis

  1. Antiphospholipid Syndrome: primary or secondary to Systemic Lupus Erythematosus? Description of a clinical case of avitaminosis D in premenopausal woman with pseudo-Cushing syndrome

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    Mauro Turrin

    2014-06-01

    Full Text Available Low vitamin D levels have been described in obese individuals and in some autoimmune diseases, such as Systemic Lupus Erythematosus (SLE and primary antiphospholipid syndrome (pAPS. In particular, more than 50% of premenopausal women with pAPS have hypovitaminosis D. In this issue we report a case of an obese, premenopausal, and hypertensive woman with pseudo-Cushing syndrome, affected by deep venous thrombosis associated with pulmonary embolism after rib fracture who presented hypovitaminosis D. 7 years before, diagnosis of pAPS had been made after the detection of thrombocytopenia (present at a young age and arterial ischemia of a lower limb. For seven years she was treated with acetylsalicylic acid without complications. We found positive anti-dsDNA antibodies, a triple antiphospholipid antibodies (aPL positivity and levels of vitamin D < 4 µg/l. The case report arises some questions: is vitamin D deficiency due to obesity or APS? Is the positivity of anti-dsDNA indicative of progression to SLE? Is preventive therapy with hydroxychloroquine indicated? Does the high-risk aPL profile justify a high-intensity and life-long anticoagulation regimen?http://dx.doi.org/10.7175/cmi.v8i2.912

  2. AN OPHTHALMIC HEALTH SURVEY IN NORTHERN IRAN

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    Kh. Moradpour

    1974-06-01

    Full Text Available The province of Rudsar is located in the Caspian littoral zone of Iran. In 1970 an ophthalmic health survey was carried out in 25 units, which were selected by random sampling in these areas. A total of 2,165 persons were examined and the results of this evaluation have been prepared in 6 parts, consisting of ophthalmic conditions and health customs, infectious eye diseases, visual status and diseases, blindness and its causes, eye complications of malnutrition, and other eye disease. The prevalence of trachoma is 24% and of conjunctivitis 11.2%, but infectious eye diseases are mild in these areas and their complications are very rare, and trachoma is deviated mainly to inclusion conjunctivitis. Visual defect are important problem in the Rudsar area; 17.8% of the persons examined of 10 years of age and over, had visual defects. The most important causes of visual defects are refraction abnor­malities, especially myopic astigmatism and contact. Visual defects are more prevalent in females than in males. Of the total number of persons examined, 2.63% had infectious eye diseases, 2.77% had blindness in at least one eye and 56.7% of the blindness was caused by cataracts. The eye complications of avitaminosis A and ariboflavinosis were observed, especially in rural areas. The establish­ment of an ophthalmic clinic, the use of a mobile dispensary unit for diagnosis, procedures for introducing patients to the ophthalmic clinic, and special procedures for the health of school children would be beneficial and are recommended for the control of ophthalmic disease. It is also necessary to have a special survey on toxoplasmosis, an investigation for clarification of the causes of differences in visual defects in males and females, and a survey on the causes of blepharitis.

  3. Trastornos neurológicos relacionados con la malnutrición en la Guerra Civil Española (1936-1939

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    Jesús M. Culebras

    2014-04-01

    Full Text Available En esta conferencia, dictada en el marco de las Jornadas Internacionales de Neurociencias, Quito, Mayo 31 a Junio 1, 2013, se hizo una exposición de lo que fueron las situaciones de hambruna acaecidas en España durante la Guerra Civil de 1936-39. Su capital, Madrid sufrió durante todo ese periodo racionamientos de alimentos, agua y leche. Esta situación dio lugar a unas condiciones que pusieron de manifiesto las relaciones entre sistema nervioso y alimentación. La población madrileña estuvo sometida a un verdadero experimento de hipo alimentación, análogo al que se puede realizar en el laboratorio. Al concluir la guerra, la Dirección General de Sanidad y el Instituto de Investigaciones Médicas, con la colaboración de la Fundación Rockefeller, realizaron una serie de encuestas clínicas y de consumo alimentario entre la población de Madrid. Hubo tres situaciones médicas que tuvieron especial relevancia durante la Guerra Civil y durante la posguerra: La epidemia de pelagra, la aparición de latirismo y el denominado síndrome de Vallecas. La aparición de casos de pelagra fue trascendental porque permitió, a partir de una avitaminosis conocida, replantearse toda la sintomatología inespecífica que se había estado observando. La pelagra pasó a ser la enfermedad carencial más prevalente, y la más claramente vinculada a la alimentación. El latirismo es una intoxicación crónica producida por la acumulación de neurotoxinas. Se debe al consumo frecuente de almortas (Lathyrus sativus . La almorta es toxica solo cuando constituye más del 30% de las calorías diarias consumidas durante un período continuado de dos a tres meses. El Latirismo volvería a afectar a los españoles durante los años 1941 y 1942, en los llamados "años del hambre" de la posguerra, cuando, debido a la escasez de alimentos, fue consumida gran cantidad de harina de almortas. Las neuropatías carenciales observadas en Madrid durante la Guerra Civil dieron

  4. Wartime diet for growing bobwhite quail

    Science.gov (United States)

    Nestler, R.B.; Llewellyn, L.; Benner, M.

    1944-01-01

    -processed meal. At the end of ten weeks only 60 per cent of the quail survived and the average live weight was only 138 grams.....When the level of dried whey was raised to 5 per cent to provide a margin of safety against abnormal feather growth (resulting partly from riboflavin deficiency), the number of survivals was nearly as high as on the diet containing 14 per cent sardine meal, but the average live weight per bird was only 139 grams. The difference between this weight and that for the birds on Diet 11 (3% dried whey) was not statistically significant.....The general rating for the diet was as high as that for Diet 11, when ground wheat replaced ground millet in the diet containing 3 per cent dried whey. Survival of birds was 5 per cent-units lower, the average live weight was about the same, and efficiency of feed utilization was higher.....Using D-activated animal sterol as a source of vitamin D and yellow corn and a good grade of alfalfa leaf meal as sources of vitamin A, fish oils were omitted from the diets without causing symptons of avitaminosis. However because of the instability of vitamin A in storage, it is advisable to include sufficient fish oil, if obtainable, in quail diets to supply at least 2,000 I. U. of vitamin A per pound of feed on a total feed basis.

  5. Net selectivity on the Great Lakes

    Science.gov (United States)

    Van Oosten, John

    1936-01-01

    -processed meal. At the end of ten weeks only 60 per cent of the quail survived and the average live weight was only 138 grams.....When the level of dried whey was raised to 5 per cent to provide a margin of safety against abnormal feather growth (resulting partly from riboflavin deficiency), the number of survivals was nearly as high as on the diet containing 14 per cent sardine meal, but the average live weight per bird was only 139 grams. The difference between this weight and that for the birds on Diet 11 (3% dried whey) was not statistically significant.....The general rating for the diet was as high as that for Diet 11, when ground wheat replaced ground millet in the diet containing 3 per cent dried whey. Survival of birds was 5 per cent-units lower, the average live weight was about the same, and efficiency of feed utilization was higher.....Using D-activated animal sterol as a source of vitamin D and yellow corn and a good grade of alfalfa leaf meal as sources of vitamin A, fish oils were omitted from the diets without causing symptons of avitaminosis. However because of the instability of vitamin A in storage, it is advisable to include sufficient fish oil, if obtainable, in quail diets to supply at least 2,000 I. U. of vitamin A per pound of feed on a total feed basis.