Leutskij, K.M.; Sovtysik, D.D.
A combined action of A-avitaminosis and ionizing radiation on the activity of retinenepalmitatesynthetase and retinenepalmitatehydrolase in the small intestine mucosa and cell membranes of white rats has been investigated. The activity of retinenepalmitatehydrolase has been shown to decrease in the irradiated animals deficient in vitamin A as compared to the control nonirradiated animals. The activity of retinenepalmitatesynthetase affected by a combination of A-avitaminosis and irradiation increases as compared to the control nonirradiated rats both in the small intestine mucosa and its cell membranes
Full Text Available Low vitamin D levels have been described in obese individuals and in some autoimmune diseases, such as Systemic Lupus Erythematosus (SLE and primary antiphospholipid syndrome (pAPS. In particular, more than 50% of premenopausal women with pAPS have hypovitaminosis D. In this issue we report a case of an obese, premenopausal, and hypertensive woman with pseudo-Cushing syndrome, affected by deep venous thrombosis associated with pulmonary embolism after rib fracture who presented hypovitaminosis D. 7 years before, diagnosis of pAPS had been made after the detection of thrombocytopenia (present at a young age and arterial ischemia of a lower limb. For seven years she was treated with acetylsalicylic acid without complications. We found positive anti-dsDNA antibodies, a triple antiphospholipid antibodies (aPL positivity and levels of vitamin D < 4 µg/l. The case report arises some questions: is vitamin D deficiency due to obesity or APS? Is the positivity of anti-dsDNA indicative of progression to SLE? Is preventive therapy with hydroxychloroquine indicated? Does the high-risk aPL profile justify a high-intensity and life-long anticoagulation regimen?http://dx.doi.org/10.7175/cmi.v8i2.912
extensive psychological 5 testing in order to update their medical record. This testing consisted of intelligence testing, personality...additional diseases are presumed to be service-connected: i. Avitaminosis ii. Chronic dystentery iii. Helminthiasis iv. Malnutrition v. Any other
Full Text Available The lecture deals with the main causes of development of hypo vitaminoses in infants and preschool children, with the emphasis made on the lack of pathognomonic signs of vitamin in sufficiency, showing the demands for the essential vitamins, and describing the natural sources of their entering the human body. The authors compare the composition of various multivitamin preparations registered in Russian the liquid dosage form convenient for use in 1ctoc7cyearcold children.Key words: avitaminosis, hypovitaminosis, prevention, infants, children.
Castelló Botía, Isabel; Pina Romero, José Aurelio
A lo largo del siglo XX, la población española fue consolidando su proceso de transición demográfica y nutricional. A medida que fue avanzando el siglo, las causas de mortalidad asociadas a nutrición de la población urbana fueron variando desde muertes por desnutrición y enfermedades infecciosas transmitidas por agua y alimentos (diarrea, clorosis, avitaminosis, fiebre tifoidea) en una primera etapa del siglo y en la etapa de la posguerra, hasta muertes asociadas a malnutrición en exceso (dia...
Leutskij, K.M.; Baran, M.M.; Batsura, A.F.
Rats were investigated to determine the separate and joint effects of A-avitaminosis and ionizing radiation on protein biosynthesis in the tunica mucosa of the small intestine (cpm/10 mg ribosomal protein; M+-m). X-raying of control and A-avitaminotic animals was shown to result in decline of protein synthesis by 20 and 47 per cent, respectively. The joint action of A-avitaminosis in and irradiation of the organism enhanced the resultant variations in protein biosynthesis, which subsequently decreased by 60 per cent. Vitamin A-alcohol, introduced in the form of an aqueous emulsion into the incubation medium in vitro, was found to affect protein biosynthesis. Retinol (3 μg/ml) introduced in vitro increased inclusion of 14 C-leucine in the proteins of the acellular protein-synthesizing system in control and A-avitaminotic animals by 15 and 38 per cent, respectively. Addition of retinol (6μg/ml) increased inclusion of 14 C-leucine in control and A-avitaminotic rats by 11 and 18 per cent, respectively. Protein synthesis was found to have reliably increased by 17 per cent following introduction of retinol (3 μg) into the incubation medium of irradiated control animals. Protein biosynthesis was assumed to be the principal irradiation-affected stage in the system of biochemical processes in the intestine [ru
Full Text Available Pregnancy has been shown to be a period of stress, during which the nutritional needs of the foetus is dependent on that of the mother. It is also a condition exhibiting increased susceptibility to oxidative stress, leading to potential damage. Ascorbic acid is a strong antioxidant as well as a reducing agent and is increasingly utilized to normalize the pro-oxidant - antioxidant balance during pregnancy. Since ascorbic acid cannot be synthesized by the body, leading to total dependence on exogenous supply in diets, there is need to evaluate the level of the vitamin in pregnant women and determine their predisposition or otherwise to avitaminosis C. Ascorbic acid levels of 60 apparently healthy pregnant women, aged between 20-40 years old and attending the antenatal clinic at the UNTH, Enugu, 60 age-matched women in their postpartum and 60 age-matched non-pregnant women (controls were assayed using the 2,4-dinitrophenyl hydrazine method. The serum ascorbic acid levels were significantly lower (P and lt;0.05 in pregnant women, showing a steady decline with gestational age increase. There were statistically significant decreases (P and lt;0.05 in the second and third trimesters whereas a significant increase (P and lt;0.05 was observed in the postpartum period, when compared to the controls. The serum levels of ascorbic acid were decreased significantly as pregnancy progresses; in spite of the supplements given Significant increases in the postpartum period may be attributed to the absence of oxidative stress and recovery from stress. Additional supplementation and increased dietary intake should be encouraged in pregnant women.
Alberto Pinzón Sánchez
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Uno de los pocos estudios hechos en el país desde el punto de vista de la Salud Pública y realizado en terreno sobre población indígena, es el estudio médico-antropológico de la Amazonia Colombiana realizado por el Doctor Ney Guzmán Gómez, de la Universidad del Valle en 1968. (1
A pesar de algunas deficiencias en el análisis antropológico, es el primer buen estudio de ese tipo, en donde se combinan los datos cualitativos y cuantitativos del nivel de salud, de un Universo Poblacional de 2.478 personas de las cuales 2.158 (87% eran indígenas, moradores de las riberas de los grandes ríos del trapecio amazónico; Putumayo, Caraparaná, Igaraparaná, Pupuña, Icatué y perteneciente a los grupos étnicos: Witotos, Borás y Ticunas.
Los indicadores más relevantes y que nos recuerdan la situación del país a comienzos de este siglo, son:
1. Pirámide poblacional con predominio de menores de 15 años.(54%
2. Elevadas tasas de natalidad 62 x 1000
3. Elevada tasa de mortalidad general 20 x 1000 – Con una elevada tasa de mortalidad de menores de una añ0 87 x 1000
4. Edad media al morir ................................25,5 años
5. Las principales causas de mortalidad:
– Gastroenteritis ...................16%
– Tuberculosis ...............10%
– Anemia.......... 6%
– Colitis. ........................... 6%
– Accidentes de selva............................. 6%
– Bronconeumonía................................. 4%
– Sarampión.................................... 2%
6. Las principales causas de morbilidad clínica fueron:
– Poli parasitismo intestinal................................... 30%
– Enfermedades respiratorias............................14%
– Enfermedades de la piel ............................. 6%
– Avitaminosis y anemia.............................. 6%