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Sample records for avitaminosis

  1. Essay on experimental avitaminosis K

    OpenAIRE

    Solano Rodríguez, Juana María; Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

    2014-01-01

    We have made an experimental test of avitaminosis K in order to study the hitipatológicas and radiological lesions in relation to haematological abnormalities and changes in prothrombin in the blood. The clinical picture observed in animals is similar in all respects to that described by Dam, Schonheyder, Almquist and colleagues. With respect to prothrombin time values ​​Quick, we note: a) Normal values: In the control animals, normal prothrombin time is 85% and the Quick time is 45 seconds. ...

  2. [Scurvy--a wrongly forgotten avitaminosis].

    Science.gov (United States)

    Bohrer, Ina; Roy, Mandy; Nager, Wido; te Wildt, Bert; Emrich, Hinderk M; Ohlmeier, Martin D

    2007-11-08

    We treated a chronic alcoholic patient who showed all the symptoms of scurvy (petechiae, greyish skin colour, areas of thinning hair on the head, gingivitis, elevated liver enzyme levels, hyponatraemia, hypalbuminaemia and hypothyroidism) at admission. Even today, alcoholics and chronically ill people in particular can develop symptoms of diet-related vitamin C deficiency.

  3. [Scurvy, a serious and rare form of avitaminosis, easily diagnosed and treated. Presentation of a case].

    Science.gov (United States)

    Gil Llano, J R; Grespo Rincón, L; Ruiz Llano, F C; Costo Campoamor, A; Mateos Polo, L; González, M A

    1995-09-01

    We report a 66 years-old man case that was admitted with abdominal wall hemorrhagic swelling ecchymosis on inferior extremities and perifollicular purpura with hyperkeratosis of the follicles, which gives it an appearance of palpable purpura, together with gingival hemorrhage and moderate anemia. He was a well-nourished sick man but who made a peculiar diet, practically free from fruit and vegetables which developed a pure and serious form of scurvy. We report this case because we consider that the features which appear are illustrative to provide the immediate clinical diagnosis of this uncommon disease, potentially mortal, but easy to diagnose, if we think about it in the adequate clinical contexts, and which it is quickly curable with the administration of ascorbic acid.

  4. [Acute neurological disclosure of B12 avitaminosis induced by folic acid administration].

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    Ammar, N; Martinez Almoyna, L; Husson, H; De Broucker, T

    2005-04-01

    A paradigmatic case of acute combined spinal cord degeneration and delirium due to inappropriate administration of folic acid in the context of chronic cobalamin deficiency is described. Rapid improvement was obtained with immediate cessation of folate administration and parenteral cobalamin supplementation. Folic acid and cobalamin prescription rules are recalled. Pathophysiological hypotheses tentatively explaining the neurotoxicity of folic acid in case of vitamin B12 deficiency are summarized.

  5. STUDIES ON A-AVITAMINOSIS IN CHICKENS : II. LESIONS OF THE UPPER ALIMENTARY TRACT AND THEIR RELATION TO SOME INFECTIOUS DISEASES.

    Science.gov (United States)

    Seifried, O

    1930-09-30

    When fowls are placed on a diet lacking in vitamin A lesions appear in the upper alimentary tract which are confined largely to the mucous glands and their ducts. Histologically it is shown that the original epithelium becomes replaced by a stratified squamous keratinizing epithelium and that secondary infections are relatively common. The ducts of the glands may be blocked leading to distention with secretions and necrotic materials. These lesions macroscopically resemble very closely certain stages of fowl-pox and the two conditions can be separated only by histological examination. It is pointed out that these lesions produced by a lack of vitamin A may enable bacteria and other viruses to enter the body.

  6. Antiphospholipid Syndrome: primary or secondary to Systemic Lupus Erythematosus? Description of a clinical case of avitaminosis D in premenopausal woman with pseudo-Cushing syndrome

    OpenAIRE

    2014-01-01

    Low vitamin D levels have been described in obese individuals and in some autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) and primary antiphospholipid syndrome (pAPS). In particular, more than 50% of premenopausal women with pAPS have hypovitaminosis D. In this issue we report a case of an obese, premenopausal, and hypertensive woman with pseudo-Cushing syndrome, affected by deep venous thrombosis associated with pulmonary embolism after rib fracture who presented hypovitamino...

  7. Antiphospholipid Syndrome: primary or secondary to Systemic Lupus Erythematosus? Description of a clinical case of avitaminosis D in premenopausal woman with pseudo-Cushing syndrome

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    Mauro Turrin

    2014-06-01

    Full Text Available Low vitamin D levels have been described in obese individuals and in some autoimmune diseases, such as Systemic Lupus Erythematosus (SLE and primary antiphospholipid syndrome (pAPS. In particular, more than 50% of premenopausal women with pAPS have hypovitaminosis D. In this issue we report a case of an obese, premenopausal, and hypertensive woman with pseudo-Cushing syndrome, affected by deep venous thrombosis associated with pulmonary embolism after rib fracture who presented hypovitaminosis D. 7 years before, diagnosis of pAPS had been made after the detection of thrombocytopenia (present at a young age and arterial ischemia of a lower limb. For seven years she was treated with acetylsalicylic acid without complications. We found positive anti-dsDNA antibodies, a triple antiphospholipid antibodies (aPL positivity and levels of vitamin D < 4 µg/l. The case report arises some questions: is vitamin D deficiency due to obesity or APS? Is the positivity of anti-dsDNA indicative of progression to SLE? Is preventive therapy with hydroxychloroquine indicated? Does the high-risk aPL profile justify a high-intensity and life-long anticoagulation regimen?http://dx.doi.org/10.7175/cmi.v8i2.912

  8. 晚期维生素K缺乏性出血症10例分析%Analysis of 10 Cases Hemorrhage Caused by Avitaminosis of K in Late Stage

    Institute of Scientific and Technical Information of China (English)

    韩铁宾; 符彦萍

    2004-01-01

    目的分析晚期维生素K缺乏性出血症的临床特点与治疗.方法系统分析10例维生素K缺乏出血症的临床症状、体征及实验室检查结果.给予维生素K 10 mg静注,1~2次/d,连用3~5 d,输新鲜冰冻血浆25 mL,1次/d,连用3 d.结果应用维生素K110 mg2 d,各种异常的实验室指标恢复正常.6例治愈,3例好转,1例死亡.结论国外采用维生素K 2 mg,新生儿1次性注射,对预防此症有一定价值;国内采用对新生儿生后第1 d开始口服维生素K 2.5 mg,连用10 d预防晚期维生素K缺乏出血症,能有效预防出血症的发生.

  9. Reduction of vitamin A deficiency and anemia in pregnancy after implementing proposed prenatal nutritional assistance Reducción de avitaminosis A y anemia en el embarazo después de la implementación propuesta de asistencia nutricional prenatal

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    C. Barbosa Chagas

    2011-08-01

    Full Text Available Introduction: Micronutrient deficiency is an unquestionable public health problem, specially anemia and vitamin A deficiency (VAD. This is due to the collective dimension of these carencies, which reflects on morbimortality rates in the maternal and infant group. Objective: to evaluate the impact of a proposal for prenatal nutritional assistance, comparing the prevalence of anemia and VAD, in pre-intervention (GI and intervention (GII groups. Methods: this is a prospective intervention study in a cohort of pregnant women. The GI group was made up of 225 the GII group of 208 pregnant adults and their respective newborns, attended a Public Maternity Ward in Rio de Janeiro, Brazil. Concentration of hemoglobin was used to diagnose anemia and a standardized interview to diagnose night blindness (XN. Results and conclusion: after adjusting for confounding variables, through logistic regression, the protective effect of intervention at the onset of anemia (OR = 0.420; IC 95% = 0.251-0.702, with a significant reduction in prevalence, of 28.4% in the GI to 16.8% in the GII, also observed at the onset of XN (OR = 0.377; IC95% = 0.187- 0.759, with a reduction in prevalence of 18.7 % in the GI to 6.2% in the GII. Nutritional intervention has a beneficial effect on maternal health, reducing nutritional deficiencies most prevalent during pregnancy and the impact of these on the obstetric ailment.Introducción: La deficiencia de micronutrientes es un problema de indudable de salud pública, especialmente la anemia y deficiencia de vitamina A (DVA. Esto es debido a la dimensión colectiva de estos carencies, que se refleja en las tasas de morbi-mortalidad en el grupo materno-infantil. Objetivo: Evaluar el impacto de un proyecto de atención nutricional prenatal, comparando la prevalencia de anemia y DVA, en la pre-intervención (GI y la intervención (GII. Métodos: se trata de una intervención prospectiva de un grupo de mujeres embarazadas. El GI consistió de 225 mujeres en el posparto y GII en 208 mujeres embarazadas y sus recién nacidos inscritos en una maternidad pública de Rio de Janeiro, Brasil. Se utilizó la concentración de hemoglobina en el diagnóstico de la anemia durante el embarazo y la entrevista estandarizada para diagnosticar la ceguera nocturna (XN. Resultados y conclusión: Tras ajustar por variables de confusión, por la regresión logística, se verificó el efecto protector de la intervención sobre la anemia (OR = 0,420, 95% CI = 0.251-0.702, con reducción significativa en la prevalencia, 28,4 en el GI y 16,8% en el GII, que también se observó en los resultados XN (OR = 0,377, IC del 95% desde 0,187 hasta 0,759, con una reducción en la prevalencia, el 18,7% al 6,2% en el GI y GII. La intervención dietética tiene efectos beneficiosos sobre la salud materna, reducir las deficiencias nutricionales más prevalentes durante el embarazo y el impacto de estos sobre el resultado del embarazo.

  10. La pellagre en Italie à la fin du XIXe siècle : les effets d'une maladie de carence

    OpenAIRE

    2011-01-01

    In many countries across the world at different times, a diet made up exclusively of maize led to the development of B3 avitaminosis, or pellagra. Caused by extremely limited nutrition, B3 avitaminosis is a deficiency disease due to insufficient intake of niacin and tryptophan. From the late eighteenth century up to the time of the First World War, pellagra was endemic in Northern Italy, particularly in the Veneto. The «sickness of the poor» and the turmoil it caused affected a single social ...

  11. A successful spontaneous pregnancy in abetalipoproteinemia: Amsterdam or the art of vitamin replacement?

    OpenAIRE

    2014-01-01

    Abetalipoproteinemia is a rare metabolic disorder that causes disturbed lipid absorption with consequent hypocholesterolaemia and liposoluble avitaminosis. The broad spectrum of presentations includes malabsorption, failure to thrive and acanthocytosis in children, while later in life expected manifestations include coagulopathy, myopathy, retinitis pigmentosa, peripheral neuropathy, hyporeflexia and ataxia. These neurological complications stem from demyelination secondary to vitamin E defic...

  12. Koro syndrome associated with alcohol-induced systemic disease in a Zulu.

    Science.gov (United States)

    Holden, T J

    1987-11-01

    A case report is presented of the genital retraction syndrome, koro, associated with alcoholic hepatitis, avitaminosis and urinary tract infection, occurring in a Zulu male. Treatment of the physical conditions resulted in resolution of the koro symptomatology. The nosological status of koro is discussed and it is proposed that the condition be regarded as a symptom-complex reaction to a variety of psychological or physical stressors rather than as a purely culture-bound syndrome.

  13. Vitamin A deficiency in quail

    Science.gov (United States)

    Nestler, R.B.; Bailey, W.W.

    1943-01-01

    Two experiments were conducted to determine the symptoms of avitaminosis A in growing and adolescent bobwhites. Chicks from parents that have received a diet rich in vitamin A may have enough stored to carry them a week or ten days on a growing diet deficient in vitamin A before symptoms of deficiency occur. The first sign is ruffled feathering, with the wing primaries standing out from the body and drooping. Ophthalmia in one or both eyes occurs and may close the eyes completely, but this condition is not severe in all cases and may not even be noticeable. Birds show poor growth, loss of appetite, and weakness before death. Under the conditions of the experiments discussed herein, death may occur in the fourth or fifth week, and mortality is high......Postmortem examination may reveal visceral gout with thick deposits of urates on the kidneys, in the ureters, on the heart, in the proventriculus, and occasionally covering all the viscera. There may also be hemorrhage of the heart and other organs....Adolescent quail reared on a diet rich in vitamin A may be able to live through the winter on a maintenance diet low in this vitamin without showing symptoms of avitaminosis, but some individuals whose storage of vitamin A in the liver is not as great as that of others may succumb to visceral gout.....A growing mash for quail which contains sufficient vitamin A when fresh may, after a period of storage, lose enough of the vitamin to cause the characteristic symptoms of avitaminosis A to appear.

  14. Diferencias regionales en la mortalidad urbana asociada a la nutrición en la España contemporánea (1900-1974)

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    Castelló Botía, Isabel; Pina Romero, José Aurelio

    2004-01-01

    A lo largo del siglo XX, la población española fue consolidando su proceso de transición demográfica y nutricional. A medida que fue avanzando el siglo, las causas de mortalidad asociadas a nutrición de la población urbana fueron variando desde muertes por desnutrición y enfermedades infecciosas transmitidas por agua y alimentos (diarrea, clorosis, avitaminosis, fiebre tifoidea) en una primera etapa del siglo y en la etapa de la posguerra, hasta muertes asociadas a malnutrición en exceso (dia...

  15. [Scientific rationale for the use of vitamins in the prophylactic and therapeutic purposes. Report 2. Vitamin deficit as a factor complicating the course disease and reducing the efficiency of medical and prophylaxis measures].

    Science.gov (United States)

    Spirichev, V B

    2011-01-01

    Vitamin insufficiency disrupting metabolism, enhances the course of any disease and hinders successful treatment. In this connection the treatment of any patient should include a correction of the existing polyvitaminic deficiency and maintain of optimal provision by all micronutrients. Using vitamins in the treatment of primary avitaminosis, correction of secondary metabolism and function of vitamins, as well as medicamental therapy and various restrictrions in a diet is undisputed. Congenital genetically defects in the metabolism and function of vitamins form a special group of diseases that require high doses of vitamins and its parenteral injection.

  16. Conjunctival impression cytology--a study of normal conjunctiva.

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    Gadkari S

    1992-01-01

    Full Text Available Conjunctival impression cytology was used to study conjunctival ocular surface in 30 normal individuals in the age group of 20 to 60 years. The cytology was graded according to the classification of Nelson. Out of 30 subjects, 26 showed the features of Grade O (average age 28.33 years and 4 showed grade 1 (average age 56.66 years. The method was very easy to perform, cheap and fast. The relationship of various cells to each other was maintained. This method can be used to study the conditions like trachoma, avitaminosis A and other disorders of conjunctival surface. It can be undertaken by a paramedical worker in an out patient clinic.

  17. Biomarkers for the differentiation of anemia and their clinical usefulness

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    Northrop-Clewes CA

    2013-03-01

    Full Text Available Christine A Northrop-Clewes,1 David I Thurnham21Nutrition Consultant, Cambridge, UK; 2Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UKAbstract: The World Health Organization defines anemia as the point at which the amount of hemoglobin in the circulation falls below World Health Organization cutoffs for specific age and sex groups. Anemia is a worldwide problem of complex etiology and is associated with many factors. The purpose of this review was to describe the biomarkers used to identify the nature of anemia in patients and in the community. The important biomarkers are the automated red cell counts, tests for nutritional deficiencies, hemoglobinopathies, and inflammation. Diseases are important potential initiators of anemia, but biomarkers of specific diseases are not included in this review, only the underlying feature common to all disease – namely, inflammation.Keywords: iron deficiency, biological markers, blood cell count, inflammation, avitaminosis, hemoglobinopathies

  18. The 'Ajuda Paralyses': history of a neuropsychiatric debate in mid-19th-century Portugal.

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    Fontoura, Paulo

    2010-10-01

    The second half of the 19th century witnessed an increasing interest in neurology and psychiatry by Portuguese physicians, in parallel with the overall development of these disciplines in other countries. This process is reflected in the numerous case report publications as well as in debates taking place at the Lisbon Society of Medical Sciences, the major scientific forum of that time. The 'Ajuda Paralyses' were a mysterious succession of epidemics that occurred during 1860-64 in the Ajuda asylum for cholera and yellow fever orphans, which were extensively discussed during 1865-66 by Bernardino Antonio Gomes, Antonio Maria Barbosa, Abel Jordão and Eduardo Motta. Studying this debate helps understand the initial stages of development and the great interest that 'nervous diseases' had for Portuguese clinicians in the mid-19th century and possibly provides one of the first modern descriptions of nutrition-related polyradiculoneuropathy and the ocular findings associated with avitaminosis A. This debate took place at a decisive time for the scientific development of neurology and psychiatry, concurrent with the widespread application of the clinical-anatomical method and neuropathology to the study of diseases of the nervous system, which would set the foundations for our own modern pathophysiological framework. Therefore, the 'Ajuda paralyses' debate also provides a good basis for a discussion on the evolution of the concepts of hysteria and psychosomatic disease and the description of peripheral neuropathy from among a wealth of other entities that did not withstand the test of science.

  19. AN OPHTHALMIC HEALTH SURVEY IN NORTHERN IRAN

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    Kh. Moradpour

    1974-06-01

    Full Text Available The province of Rudsar is located in the Caspian littoral zone of Iran. In 1970 an ophthalmic health survey was carried out in 25 units, which were selected by random sampling in these areas. A total of 2,165 persons were examined and the results of this evaluation have been prepared in 6 parts, consisting of ophthalmic conditions and health customs, infectious eye diseases, visual status and diseases, blindness and its causes, eye complications of malnutrition, and other eye disease. The prevalence of trachoma is 24% and of conjunctivitis 11.2%, but infectious eye diseases are mild in these areas and their complications are very rare, and trachoma is deviated mainly to inclusion conjunctivitis. Visual defect are important problem in the Rudsar area; 17.8% of the persons examined of 10 years of age and over, had visual defects. The most important causes of visual defects are refraction abnor­malities, especially myopic astigmatism and contact. Visual defects are more prevalent in females than in males. Of the total number of persons examined, 2.63% had infectious eye diseases, 2.77% had blindness in at least one eye and 56.7% of the blindness was caused by cataracts. The eye complications of avitaminosis A and ariboflavinosis were observed, especially in rural areas. The establish­ment of an ophthalmic clinic, the use of a mobile dispensary unit for diagnosis, procedures for introducing patients to the ophthalmic clinic, and special procedures for the health of school children would be beneficial and are recommended for the control of ophthalmic disease. It is also necessary to have a special survey on toxoplasmosis, an investigation for clarification of the causes of differences in visual defects in males and females, and a survey on the causes of blepharitis.

  20. Trastornos neurológicos relacionados con la malnutrición en la Guerra Civil Española (1936-1939

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    Jesús M. Culebras

    2014-04-01

    Full Text Available En esta conferencia, dictada en el marco de las Jornadas Internacionales de Neurociencias, Quito, Mayo 31 a Junio 1, 2013, se hizo una exposición de lo que fueron las situaciones de hambruna acaecidas en España durante la Guerra Civil de 1936-39. Su capital, Madrid sufrió durante todo ese periodo racionamientos de alimentos, agua y leche. Esta situación dio lugar a unas condiciones que pusieron de manifiesto las relaciones entre sistema nervioso y alimentación. La población madrileña estuvo sometida a un verdadero experimento de hipo alimentación, análogo al que se puede realizar en el laboratorio. Al concluir la guerra, la Dirección General de Sanidad y el Instituto de Investigaciones Médicas, con la colaboración de la Fundación Rockefeller, realizaron una serie de encuestas clínicas y de consumo alimentario entre la población de Madrid. Hubo tres situaciones médicas que tuvieron especial relevancia durante la Guerra Civil y durante la posguerra: La epidemia de pelagra, la aparición de latirismo y el denominado síndrome de Vallecas. La aparición de casos de pelagra fue trascendental porque permitió, a partir de una avitaminosis conocida, replantearse toda la sintomatología inespecífica que se había estado observando. La pelagra pasó a ser la enfermedad carencial más prevalente, y la más claramente vinculada a la alimentación. El latirismo es una intoxicación crónica producida por la acumulación de neurotoxinas. Se debe al consumo frecuente de almortas (Lathyrus sativus . La almorta es toxica solo cuando constituye más del 30% de las calorías diarias consumidas durante un período continuado de dos a tres meses. El Latirismo volvería a afectar a los españoles durante los años 1941 y 1942, en los llamados "años del hambre" de la posguerra, cuando, debido a la escasez de alimentos, fue consumida gran cantidad de harina de almortas. Las neuropatías carenciales observadas en Madrid durante la Guerra Civil dieron

  1. Suscetibilidade de pintos ao virus amarílico neurotrópico

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    Herminio Linhares

    1943-01-01

    gastric route. 3. During first days virus may be found, occasionally in the lungs, liver, spleen and kidneys; some days afterwards, no chicks showed virus in other organs than brain, in which virus persists up to 10th day post-intraperitoneal inoculation and up to 15th day after the intracerebral inoculation, and perhaps till later. We have however, not been able to isolate the virus from excretions. 4. There does not seem to be any difference in susceptibillity to the yellow fever virus, on chicks with B avitaminosis. 5. Detectable immune bodies appear by 10-11 day after intraperitoneal and intracerebral inoculation, at time, that many of some chicks still have virus in the brain. 6. Age has a marked influence on the development of immunity, in chicks inoculated by intraperitoneal route. 7. The multiplication and circulation of virus after intradermal inoculation of 50 to 160 M.L.D., renders possible to suggest that infected mosquitoes can difuse the virus among chicks and, perhaps, to other birds, a few days old.

  2. Net selectivity on the Great Lakes

    Science.gov (United States)

    Van Oosten, John

    1936-01-01

    -processed meal. At the end of ten weeks only 60 per cent of the quail survived and the average live weight was only 138 grams.....When the level of dried whey was raised to 5 per cent to provide a margin of safety against abnormal feather growth (resulting partly from riboflavin deficiency), the number of survivals was nearly as high as on the diet containing 14 per cent sardine meal, but the average live weight per bird was only 139 grams. The difference between this weight and that for the birds on Diet 11 (3% dried whey) was not statistically significant.....The general rating for the diet was as high as that for Diet 11, when ground wheat replaced ground millet in the diet containing 3 per cent dried whey. Survival of birds was 5 per cent-units lower, the average live weight was about the same, and efficiency of feed utilization was higher.....Using D-activated animal sterol as a source of vitamin D and yellow corn and a good grade of alfalfa leaf meal as sources of vitamin A, fish oils were omitted from the diets without causing symptons of avitaminosis. However because of the instability of vitamin A in storage, it is advisable to include sufficient fish oil, if obtainable, in quail diets to supply at least 2,000 I. U. of vitamin A per pound of feed on a total feed basis.

  3. Wartime diet for growing bobwhite quail

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    Nestler, R.B.; Llewellyn, L.; Benner, M.

    1944-01-01

    -processed meal. At the end of ten weeks only 60 per cent of the quail survived and the average live weight was only 138 grams.....When the level of dried whey was raised to 5 per cent to provide a margin of safety against abnormal feather growth (resulting partly from riboflavin deficiency), the number of survivals was nearly as high as on the diet containing 14 per cent sardine meal, but the average live weight per bird was only 139 grams. The difference between this weight and that for the birds on Diet 11 (3% dried whey) was not statistically significant.....The general rating for the diet was as high as that for Diet 11, when ground wheat replaced ground millet in the diet containing 3 per cent dried whey. Survival of birds was 5 per cent-units lower, the average live weight was about the same, and efficiency of feed utilization was higher.....Using D-activated animal sterol as a source of vitamin D and yellow corn and a good grade of alfalfa leaf meal as sources of vitamin A, fish oils were omitted from the diets without causing symptons of avitaminosis. However because of the instability of vitamin A in storage, it is advisable to include sufficient fish oil, if obtainable, in quail diets to supply at least 2,000 I. U. of vitamin A per pound of feed on a total feed basis.

  4. 腹腔镜胃袖状切除术联合十二指肠空肠吻合术与腹腔镜Roux-en-Y胃旁路术治疗非肥胖型2型糖尿病的疗效比较%Comparison of the efficacies of laparoscopic sleeve gastrectomy with duodenojejunal bypass and laparoscopic Roux-en-Y gastric bypass in the treatment of patients with non-obese type 2 diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    梁辉; 管蔚; 刘欢; 曹庆; 苗毅

    2013-01-01

    .8) mmol/L and (5.7 ± 0.3) mmol/L in the Sleeve + DJB group,and (9.9 ± 1.2) mmol/L,(6.9 ± 0.8) mmol/L,(6.6 ± 2.2) mmol/L and (5.6 ± 0.8) mmol/L,with no significant difference between the 2 groups (F =1.670,2.932,0.444,0.158,P > 0.05).The levels of HbAle before operation and at postoperative months 1,3,6 were 7.4%± 1.4%,6.5% ±0.6%,5.7%±0.5%,5.9% ±0.6% in the Sleeve + DJB group,and 7.7%± 2.0%,6.8% ± 1.3%,5.7%±0.8%,5.6% ± 1.1% in the RYGB group,with no significant difference between the 2 groups (F =0.055,0.125,0.005,0.286,P > 0.05).The remission rates of T2DM of the Sleeve + DJB group and the RYGB group were 14/15 and 74.1% (20/27) at postoperative month 6,with no significant difference between the 2 groups (x2 =2.320,P > 0.05).The decrease rate of BMI of the Sleeve + DJB group and the RYGB group were 18.2%±9.5% and 21.2% ± 4.9%,with no significant difference between the 2 groups (t =0.982,P >0.05).The numbers of patients with postoperative anaemia,avitaminosis and diarrhea were 0,0,2 in the Sleeve + DJB group and 3,2,6 in the RYGB group,with no significant difference between the 2 groups (x2=1.795,1.167,0.908,P >0.05).The BMIs of all the patients were above 19 kg/m2.Conclusion The effects and incidence of postoperative complications of Sleeve + DJB for the treatment of T2DM are comparable to those of RYGB.Sleeve + DJB has less interference on the nutritional condition of patients compared with RYGB.