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Sample records for av block modifiable

  1. Syncope and Idiopathic (Paroxysmal) AV Block.

    Science.gov (United States)

    Brignole, Michele; Deharo, Jean-Claude; Guieu, Regis

    2015-08-01

    Syncope due to idiopathic AV block is characterized by: 1) ECG documentation (usually by means of prolonged ECG monitoring) of paroxysmal complete AV block with one or multiple consecutive pauses, without P-P cycle lengthening or PR interval prolongation, not triggered by atrial or ventricular premature beats nor by rate variations; 2) long history of recurrent syncope without prodromes; 3) absence of cardiac and ECG abnormalities; 4) absence of progression to persistent forms of AV block; 5) efficacy of cardiac pacing therapy. The patients affected by idiopathic AV block have low baseline adenosine plasma level values and show an increased susceptibility to exogenous adenosine. The APL value of the patients with idiopathic AV block is much lower than patients affected by vasovagal syncope who have high adenosine values. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Phase 4 paroxysmal AV block in a patient with scleroderma.

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    Butschek, Ross; Powell, Brian D; Littmann, Laszlo

    2013-01-01

    A 72-year-old man with limited cutaneous systemic scleroderma was hospitalized for two episodes of witnessed syncope. The baseline 12-lead electrocardiogram was normal but on telemetry there were numerous episodes of paroxysmal AV block with asystolic periods of up to 7.5 s duration. Analysis of the rhythm strips revealed phase 4 intra-His bundle block characterized by critical P-P intervals that triggered the AV block, and a narrow range of junctional escape to subsequent P wave intervals that were required to release the AV block. A dual chamber pacemaker was implanted. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Association of temporary complete AV block and junctional ectopic tachycardia after surgery for congenital heart disease.

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    Paech, Christian; Dähnert, Ingo; Kostelka, Martin; Mende, Meinhardt; Gebauer, Roman

    2015-01-01

    Junctional ectopic tachycardia (JET) is a postoperative complication with a mortality rate of up to 14% after surgery for congenital heart disease. This study evaluated the risk factors of JET and explored the association of postoperative temporary third degree atrioventricular (AV) block and the occurrence of JET. Data were collected retrospectively from 1158 patients who underwent surgery for congenital heart disease. The overall incidence of JET was 2.8%. Temporary third degree AV block occurred in 1.6% of cases. Permanent third degree AV block requiring pacemaker implantation occurred in 1% of cases. In all, 56% of patients with JET had temporary AV block (P AV block (P = 0.56). temporary third degree AV block did not suffer from JET. A correlation between temporary third degree AV block and postoperative JET could be observed. The risk factors identified for JET include younger age groups at the time of surgery, longer aortic cross clamping time and surgical procedures in proximity to the AV node.

  4. [Total A-V block due to tuberous sclerosis. A case report].

    Science.gov (United States)

    Valente, N; Guidugli Neto, J; De Paola, A A; Pimenta, J

    1989-10-01

    Tuberous sclerosis is a neurologic disease affecting various organs with a triade: sebaceum adenoma, mental retardation and seizures. This report presents a case of a patient with tuberous sclerosis and third degree A-V block with complete invasive and non-invasive evaluation. The patient had sincope and complete A-V block with QRS complexes showing right bundle branch block morphology. The echocardiogram showed dilated cardiomyopathy with diffuse left ventricular dysfunction and had normal coronary arteriography. The eletrophysiologic evaluation showed complete infra-hisian A-V block and QRS with left bundle branch block pattern with normal sinus nodal and A-V nodal function. It was not possible to induce ventricular tachtyarrhythmias up to two extrastimuli. Histologic study showed normal myocardium under light and electronic microscopy. After permanent VVI pacemaker implant, the patient in follow-up for 16 years. This case seems to be the first in the international medical literature of tuberous sclerosis with complete heart block.

  5. Baseline HV-interval predicts complete AV-block secondary to transcatheter aortic valve implantation.

    Science.gov (United States)

    Shin, Dong-In; Merx, Marc W; Meyer, Christian; Kirmanoglou, Kiriakos; Hellhammer, Katharina; Ohlig, Jan; Katsani, Dimitra; Zeus, Tobias; Westenfeld, Ralf; Eickholt, Christian; Linke, Axel; Kelm, Malte

    2015-10-01

    Development of AV-block is a frequent complication associated with transcatheter aortic valve implantation (TAVI). To date little is known about the predictive value of the HV-interval prior to TAVI with respect to the risk of AV-block development. HV-interval was determined in 25 consecutive elderly patients with severe aortic valve stenosis (AS) before and immediately after TAVI. All patients subsequently underwent TAVI and 8 of these 25 patients (32%) developed complete AV-block during the TAVI procedure requiring permanent pacemaker implantation. Six of these 8 patients (75%) had marked HV prolongation (>54 ms). Pre-procedural HV-interval was significantly prolonged in the subgroup developing complete AV-block (62.1 ms±13.0 vs 49.2 ms±12.9; P=0.029). Prolongation of the HV-interval above 54 ms was associated with a higher rate of complete AV-block (sensitivity 75.0%, specificity 77.8%, P=0.01). HV-interval was prolonged in approximately one third of our elderly patients with aortic valve stenosis and associated with a high rate of complete AV-block following TAVI. HV-interval is easily obtained during TAVI screening procedures, thus facilitating identification of patients at risk for complete AV-block due to TAVI and consequently enabling bespoke risk management.

  6. Simplified Cardioneuroablation in the Treatment of Reflex Syncope, Functional AV Block, and Sinus Node Dysfunction.

    Science.gov (United States)

    Aksu, Tolga; Golcuk, Ebru; Yalin, Kivanç; Guler, Tümer Erdem; Erden, Ismail

    2016-01-01

    Cardio neuroablation (CNA) is a lesser-known technique for management of patients with excessive vagal activation on the basis of radiofrequency catheter ablation (RFCA) of the areas related to the three main autonomic ganglia around the heart. We investigated the effectiveness of selective and/or stepwise RFCA of these areas via right atrium (RA) and/or left atrium (LA) in the patients with recurrent syncope due to excessive vagal activity. Twenty-two patients presenting symptomatic functional bradyarrhythmias, neurally mediated reflex syncope (NMS), symptomatic atrioventricular (AV) block, and symptomatic sinus node dysfunction (SND; number = 8, 7, 7, respectively) were enrolled. The three main paracardiac ganglia were targeted via RA and LA in the patients with NMS and SND. The procedure was performed via RA in the patients with AV block, followed by RFCA of all ganglia via LA, if AV conduction disorder persists. The sites showing fragmented potentials were identified by electrical mapping and verified by high-frequency stimulation and ablated until atrial electrical potential was completely eliminated (AV block. Despite the increased heart rate, the resolution of AV block after the RFCA could not be achieved in one patient who had partial resolution with atropine infusion on admission. CNA may be an alternative and safe strategy to reduce NMS episodes, and to treat functional AV block and symptomatic SND, especially in young patients. © 2015 Wiley Periodicals, Inc.

  7. Novel modes and adaptive block scanning order for intra prediction in AV1

    Science.gov (United States)

    Hadar, Ofer; Shleifer, Ariel; Mukherjee, Debargha; Joshi, Urvang; Mazar, Itai; Yuzvinsky, Michael; Tavor, Nitzan; Itzhak, Nati; Birman, Raz

    2017-09-01

    The demand for streaming video content is on the rise and growing exponentially. Networks bandwidth is very costly and therefore there is a constant effort to improve video compression rates and enable the sending of reduced data volumes while retaining quality of experience (QoE). One basic feature that utilizes the spatial correlation of pixels for video compression is Intra-Prediction, which determines the codec's compression efficiency. Intra prediction enables significant reduction of the Intra-Frame (I frame) size and, therefore, contributes to efficient exploitation of bandwidth. In this presentation, we propose new Intra-Prediction algorithms that improve the AV1 prediction model and provide better compression ratios. Two (2) types of methods are considered: )1( New scanning order method that maximizes spatial correlation in order to reduce prediction error; and )2( New Intra-Prediction modes implementation in AVI. Modern video coding standards, including AVI codec, utilize fixed scan orders in processing blocks during intra coding. The fixed scan orders typically result in residual blocks with high prediction error mainly in blocks with edges. This means that the fixed scan orders cannot fully exploit the content-adaptive spatial correlations between adjacent blocks, thus the bitrate after compression tends to be large. To reduce the bitrate induced by inaccurate intra prediction, the proposed approach adaptively chooses the scanning order of blocks according to criteria of firstly predicting blocks with maximum number of surrounding, already Inter-Predicted blocks. Using the modified scanning order method and the new modes has reduced the MSE by up to five (5) times when compared to conventional TM mode / Raster scan and up to two (2) times when compared to conventional CALIC mode / Raster scan, depending on the image characteristics (which determines the percentage of blocks predicted with Inter-Prediction, which in turn impacts the efficiency of the new

  8. Patients' and procedural characteristics of AV-block during slow pathway modulation for AVNRT-single center 10year experience.

    Science.gov (United States)

    Wasmer, Kristina; Dechering, Dirk G; Köbe, Julia; Leitz, Patrick; Frommeyer, Gerrit; Lange, Phillip S; Kochhäuser, Simon; Reinke, Florian; Pott, Christian; Mönnig, Gerold; Breithardt, Günter; Eckardt, Lars

    2017-10-01

    Permanent AV-block is a recognized and feared complication of slow pathway modulation for AVNRT. We aimed to assess incidence of transient and permanent AV-block as well as consequences of transient AV-block in a large contemporary AVNRT ablation cohort. We searched our single center prospective ablation database for occurrence of transient and permanent AV-block during slow pathway modulation between January 2004 and October 2015. We analyzed patients' and procedural characteristics as well as outcome of patients in whom transient or permanent AV-block occurred. Of 9170 patients who underwent a catheter ablation at our institution between January 2004 and October 2015, 2101 patients (64% women, mean age 50±18years) underwent slow pathway modulation. In three patients, permanent AV-block occurred during RF application. Additional two patients had transient AV-block that recovered (after a few minutes and 25min), but recurred within two days of the procedure. All five patients underwent dual chamber pacemaker implantation (0.2%). Transient AV-block related to RF delivery occurred in 44 patients (2%). Transient mechanical AV-block occurred in additional 17 patients (0.8%). In 12 patients, ablation was continued despite transient AV-block. One of these patients developed permanent AV-block. Permanent AV-block following slow pathway modulation is a rare event, occurring in 0.2% of patients in a large contemporary single center cohort. Transient AV-block is more frequent (2%). Copyright © 2017 Elsevier B.V. All rights reserved.

  9. First-degree AV block-an entirely benign finding or a potentially curable cause of cardiac disease?

    Science.gov (United States)

    Holmqvist, Fredrik; Daubert, James P

    2013-05-01

    First-degree atrioventricular (AV) block is a delay within the AV conduction system and is defined as a prolongation of the PR interval beyond the upper limit of what is considered normal (generally 0.20 s). Up until recently, first-degree AV block was considered an entirely benign condition. In fact, some complain that it is a misnomer since there is only delay and no actual block in the AV conduction system (usually within the AV node). However, it has long been acknowledged that extreme forms of first-degree AV block (typically a PR interval exceeding 0.30 s) can cause symptoms due to inadequate timing of atrial and ventricular contractions, similar to the so-called pacemaker syndrome. Consequently, the current guidelines state that permanent pacemaker implantation is reasonable for first-degree AV block with symptoms similar to those of pacemaker syndrome or with hemodynamic compromise, but also stresses that there is little evidence to suggest that pacemakers improve survival in patients with isolated first-degree AV block. Recent reports suggest that it may be time to revisit the impact of first-degree AV block. Also, several findings in post hoc analyses of randomized device trials give important insights in possible treatment options. The present review aims to provide an update on the current knowledge concerning the impact of first-degree AV block and also to address the issue of pacing in patients with this condition. ©2013, Wiley Periodicals, Inc.

  10. A Heart too Drunk to Drive; AV Block following Acute Alcohol Intoxication.

    Science.gov (United States)

    van Stigt, Arthur H; Overduin, Ruben J; Staats, Liza C; Loen, Vera; van der Heyden, Marcel A G

    2016-02-29

    Acute excessive alcohol consumption is associated with heart rhythm disorders like atrial fibrillation but also premature ventricular contractions, collectively known as the "holiday heart syndrome". More rarely but clinically significant are reports of atrioventricular (AV) conduction disturbances in binge drinkers with no underlying heart disease or chronic alcohol consumption. To obtain better insights into common denominators and the potential underlying mechanisms we collected and compared individual case reports of AV block following acute alcohol intoxication in otherwise healthy people. By screening PubMed, Google Scholar, Scopus and JSTOR, fifteen cases were found of which eight were sufficiently documented for full analysis. Blood alcohol levels ranged from 90 to 958 mg/dl (19 to 205 mM). Second and third degree AV block was observed most (6/8) albeit that in two of these patients a vagal stimulus led to deterioration from first into higher order AV block. In all cases, patients reverted to normal sinus rhythm upon becoming sober again. Mildly lowered body temperature (35.9 ± 0.5°C) was observed but can be excluded as a major cause of conduction blockade. We hypothesize that ethanol induced partial inhibition of calcium and potentially also sodium currents in conductive tissue structures may be one of the mechanisms of conduction slowing and block that may become exaggerated upon increased vagal tone. An impairment of gap junction function cannot be excluded as a contributing factor. In conclusion, cases of documented alcohol induced AV block are very rare but events can occur at relatively low serum alcohol levels which should prompt to awareness of this phenomenon in alcohol intoxicated patients.

  11. Complete A-V block: incidental or a part of cor triatriatum dexter.

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    Guler, Y; Akgun, T; Toprak, C; Guler, A; Esen, A M

    2014-05-01

    Cor triatriatum dexter (CTD) is an extremely rare cardiac anomaly in which the right atrium is divided into two distinct chambers by a membrane. The persistence of the right valve of sinus venosus results in a complete septation of the right atrium. This anomaly is frequently associated with other right-sided cardiac abnormalities. Its clinical manifestation and the need for intervention are determined by the number and the size of the fenestrations on the membrane, associated cardiac anomalies and arrhythmias. We describe a case of CTD in a patient with complete atrioventricular (A-V) block.

  12. Prevalence of E/A wave fusion and A wave truncation in DDD pacemaker patients with complete AV block under nominal AV intervals.

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    Poller, Wolfram C; Dreger, Henryk; Schwerg, Marius; Melzer, Christoph

    2015-01-01

    Optimization of the AV-interval (AVI) in DDD pacemakers improves cardiac hemodynamics and reduces pacemaker syndromes. Manual optimization is typically not performed in clinical routine. In the present study we analyze the prevalence of E/A wave fusion and A wave truncation under resting conditions in 160 patients with complete AV block (AVB) under the pre-programmed AVI. We manually optimized sub-optimal AVI. We analyzed 160 pacemaker patients with complete AVB, both in sinus rhythm (AV-sense; n = 129) and under atrial pacing (AV-pace; n = 31). Using Doppler analyses of the transmitral inflow we classified the nominal AVI as: a) normal, b) too long (E/A wave fusion) or c) too short (A wave truncation). In patients with a sub-optimal AVI, we performed manual optimization according to the recommendations of the American Society of Echocardiography. All AVB patients with atrial pacing exhibited a normal transmitral inflow under the nominal AV-pace intervals (100%). In contrast, 25 AVB patients in sinus rhythm showed E/A wave fusion under the pre-programmed AV-sense intervals (19.4%; 95% confidence interval (CI): 12.6-26.2%). A wave truncations were not observed in any patient. All patients with a complete E/A wave fusion achieved a normal transmitral inflow after AV-sense interval reduction (mean optimized AVI: 79.4 ± 13.6 ms). Given the rate of 19.4% (CI 12.6-26.2%) of patients with a too long nominal AV-sense interval, automatic algorithms may prove useful in improving cardiac hemodynamics, especially in the subgroup of atrially triggered pacemaker patients with AV node diseases.

  13. Prevalence of E/A wave fusion and A wave truncation in DDD pacemaker patients with complete AV block under nominal AV intervals.

    Directory of Open Access Journals (Sweden)

    Wolfram C Poller

    Full Text Available Optimization of the AV-interval (AVI in DDD pacemakers improves cardiac hemodynamics and reduces pacemaker syndromes. Manual optimization is typically not performed in clinical routine. In the present study we analyze the prevalence of E/A wave fusion and A wave truncation under resting conditions in 160 patients with complete AV block (AVB under the pre-programmed AVI. We manually optimized sub-optimal AVI.We analyzed 160 pacemaker patients with complete AVB, both in sinus rhythm (AV-sense; n = 129 and under atrial pacing (AV-pace; n = 31. Using Doppler analyses of the transmitral inflow we classified the nominal AVI as: a normal, b too long (E/A wave fusion or c too short (A wave truncation. In patients with a sub-optimal AVI, we performed manual optimization according to the recommendations of the American Society of Echocardiography.All AVB patients with atrial pacing exhibited a normal transmitral inflow under the nominal AV-pace intervals (100%. In contrast, 25 AVB patients in sinus rhythm showed E/A wave fusion under the pre-programmed AV-sense intervals (19.4%; 95% confidence interval (CI: 12.6-26.2%. A wave truncations were not observed in any patient. All patients with a complete E/A wave fusion achieved a normal transmitral inflow after AV-sense interval reduction (mean optimized AVI: 79.4 ± 13.6 ms.Given the rate of 19.4% (CI 12.6-26.2% of patients with a too long nominal AV-sense interval, automatic algorithms may prove useful in improving cardiac hemodynamics, especially in the subgroup of atrially triggered pacemaker patients with AV node diseases.

  14. Adaptive CRT in patients with normal AV conduction and left bundle branch block: Does QRS duration matter?

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    Yamasaki, Hiro; Lustgarten, Daniel; Cerkvenik, Jeffrey; Birnie, David; Gasparini, Maurizio; Lee, Kathy Lia-Fun; Sekiguchi, Yukio; Varma, Niraj; Lemke, Bernd; Starling, Randall C; Aonuma, Kazutaka

    2017-08-01

    Adaptive cardiac resynchronization therapy (aCRT) is a dynamic optimization algorithm which paces only the left ventricle (LV) when atrio-ventricular (AV) conduction is normal, thus reducing right ventricular (RV) pacing. However, the impact of QRS duration on aCRT efficacy remains uncertain. We examined whether QRS duration impacts aCRT effectiveness in patients with left bundle branch block (LBBB) and preserved AV conduction. Randomized patients in the Adaptive CRT trial, which enrolled NYHA III/IV patients, were used in this analysis. Patients were randomized to receive aCRT or echo-optimized bi-ventricular CRT (control arm). Endpoints for this analysis were clinical composite score (CCS) at 6months post-implant and time to first heart failure (HF) hospitalization or death. Among the 199 patients with LBBB and normal AV intervals at baseline, 80 patients (40%) had a baseline moderately wide QRS of 120-150ms. In this subgroup, a greater proportion of aCRT patients had an improved CCS (79% vs. 50%) at 6months compared to the control group (p=0.03). There was also a trend toward a lower risk of death or HF hospitalization (hazard ratio: 0.53; 95% CI: 0.24-1.15; p=0.10) in the moderately wide QRS subgroup with aCRT compared to the control arm. In the wide QRS subgroup, the efficacy was comparable in both treatment arms. Adaptive CRT was associated with improved patient outcomes over echo-optimized bi-ventricular CRT in patients with preserved AV conduction, LBBB, and moderately wide QRS. The adaptive cardiac resynchronization therapy trial (ClinicalTrials.gov Identifier: NCT00980057) was sponsored by Medtronic plc, Mounds View, MN. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Third-degree AV block from extended-release diltiazem ingestion in a nine-month-old.

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    Wills, Brandon K; Liu, J Marc; Wahl, Michael

    2010-04-01

    Calcium channel blocker (CCB) overdose is associated with dysrhythmias and atrioventricular (AV) block, however, experience with infant CCB overdose is limited. A 9-month-old girl was found playing with tablets of extended-release diltiazem 120 mg. The patient had two episodes of emesis, which contained pill fragments, and was brought to the Emergency Department (ED) 4.5 h after being found. Vital signs were: rectal temperature 37.1 degrees C, pulse 87 beats/min, respiratory rate 30-40 breaths/min, blood pressure 72/48 mm Hg, and oxygen saturation (SpO(2)) 99% on room air. Otherwise, the patient was well-appearing, with normal skin color and examination. The electrocardiogram revealed third-degree atrioventricular block with a ventricular rate of 90 beats/min, QRS 68 ms, and QTc 411 ms. Atropine 0.1 mg i.v. was given, which increased the heart rate to 100-110 beats/min. Calcium gluconate 500 mg was also given intravenously. Laboratory evaluation revealed bicarbonate 17 mEq/L, anion gap 16, and glucose 129 mg/dL. On hospital day 1, the patient was noted to have a junctional rhythm with a rate of 90-100, and systolic blood pressure of 80-90 mm Hg. No additional medications were given. Early on day 2, the patient converted spontaneously to a normal sinus rhythm and was discharged approximately 42 h after presentation to the ED. In addition to bradycardia and hypotension, this 9-month-old patient manifested third-degree AV block after ingesting extended-release diltiazem. Copyright 2010 Elsevier Inc. All rights reserved.

  16. Adverse effects of first-degree AV-block in patients with sinus node dysfunction: data from the mode selection trial.

    Science.gov (United States)

    Holmqvist, Fredrik; Hellkamp, Anne S; Lee, Kerry L; Lamas, Gervasio A; Daubert, James P

    2014-09-01

    Patients with a pacing indication and first-degree atrioventricular (AV)-block pose a clinical challenge. The prognostic impact of first-degree AV-block in patients with sinus node dysfunction and the impact of pacing in this setting are not known. In the Mode Selection Trial (MOST), 2,010 patients with sinus node dysfunction were randomized to either dual-chamber (DDD-R) or ventricular (VVI-R) pacing and followed for a median of 33 months. We report on clinical outcomes in patients with first-degree AV-block (PR interval > 200 ms) compared with patients who had a normal PR interval at baseline. Patients with first-degree AV-block (n = 378) were older (median [Q1, Q3]; 76 [70, 82] years vs 73 [66, 79] years, PAV-conduction (n = 1,159). In multivariable analyses, patients with first-degree AV-block were at greater risk of death, stroke, or heart failure hospitalization (hazard ratio [HR] 1.31, 95% confidence interval [CI] 1.06-1.61, P = 0.013). A trend towards a higher incidence of atrial fibrillation was seen (HR 1.24, 95% CI 0.98-1.55, P = 0.069). No significant interactions between pacing arm and prolonged versus normal PR were found for any endpoint, and hazard ratios were consistent across subgroups. First-degree AV-block is associated with more advanced disease but is still an independent predictor of poor clinical outcome. Neither DDD-R nor VVI-R pacing, as employed in MOST, eliminate the negative effects associated with first-degree AV-block. ©2014 Wiley Periodicals, Inc.

  17. A new method of building permanent A-V block model: ablating his-bundle potential through femoral artery with pre-implanted biventricular pacemaker.

    Science.gov (United States)

    Cheng, Zheng; Hai-ge, Ye; Jin, Li; Wan-chun, Ye; Lu-ping, Wang; Yue-chun, Li; Jia-Feng, Lin

    2014-11-20

    To explore the feasibility of a new method of achieving a permanent A-V block animal model. 16 beagles were randomly divided into two groups based on the method of their pre-implanted biventricular pacemakers. (1) In the first group (8 beagles), the A-V block model was achieved by ablating his-bundle potential at the site of the left ventricular superior-septum, under the aortic sinus, through femoral artery. (2) In the second group (8 beagles), the A-V block model was achieved by ablating his-bundle potential at the triangle of Koch, through femoral vein. A complete A-V block model was achieved as a standard in this study. The success rates, intraoperative arrhythmias, operative and X-ray exposure time, intraoperative bleeding amount were assessed in this two groups, both animal models were followed up for four weeks and then fasted to monitor myocardial pathological changes. The success rate of the first group, which with fewer intraoperative arrhythmias, and less operative and X-ray exposure time, was significantly higher than the second group. Compared with traditional animal method, our new method of ablating his-bundle potential at the left ventricle from the femoral artery has a higher success rate, fewer occurrence of malignant arrhythmias, and less operation and X-ray time. Thus, our new method should be preferred in the building of Permanent A-V Block Model.

  18. Morphological studies on block copolymer modified PA 6 blends

    Science.gov (United States)

    Poindl, M.; Bonten, C.

    2014-05-01

    Recent studies show that compounding polyamide 6 (PA 6) with a PA 6 polyether block copolymers made by reaction injection molding (RIM) or continuous anionic polymerization in a reactive extrusion process (REX) result in blends with high impact strength and high stiffness compared to conventional rubber blends. In this paper, different high impact PA 6 blends were prepared using a twin screw extruder. The different impact modifiers were an ethylene propylene copolymer, a PA PA 6 polyether block copolymer made by reaction injection molding and one made by reactive extrusion. To ensure good particle matrix bonding, the ethylene propylene copolymer was grafted with maleic anhydride (EPR-g-MA). Due to the molecular structure of the two block copolymers, a coupling agent was not necessary. The block copolymers are semi-crystalline and partially cross-linked in contrast to commonly used amorphous rubbers which are usually uncured. The combination of different analysis methods like atomic force microscopy (AFM), transmission electron microscopy (TEM) and scanning electron microscopy (SEM) gave a detailed view in the structure of the blends. Due to the partial cross-linking, the particles of the block copolymers in the blends are not spherical like the ones of ethylene propylene copolymer. The differences in molecular structure, miscibility and grafting of the impact modifiers result in different mechanical properties and different blend morphologies.

  19. PROLONGED MULTIPLE SPASMS OF SMOOTH CORONARY ARTERIES PRESENTING AS ACUTE MIOCARDIAL INFARCTION, COMPLETE AV BLOCK AND SYNCOPE

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    Franci Cesar

    2004-11-01

    Full Text Available Background. A variant form of angina pectoris (VAP is caused by coronary vessel spasm and occures in patients with and without varying degrees of obstructive coronary artery disease. Although the prognosis of VAP without significant organic stenosis is generally good, multivessel spasm is associated with a high risk of life-threatening abnormalities of rhythm and conduction.Patient and methods. We describe a patient who presented with prolonged chest pain, associated with hypotension, lost of consciousness, complete AV block and widespread ST segment elevations consistent with inferoanterior acute myocardial infarction. Urgent selective coronary angiography revealed spasms in right coronary artery and in left circumflex artery that were relieved by intracoronary injection of nitroglycerin. All coronary arteries were otherwise patient, without signs of atherosclerosis. The patient was treated with diltiazem and nitrates. She made a complete recovery and resumed her normal activities.Conclusions. Simultaneous multiple spasms of native coronary arteries represent a rare syndrome characterized by significantly higher incidence of potentially life-threatening arrhythmia. Less commonly, prolonged coronary spasm may mimic acute myocardial infarction. Modern management of acute coronary syndromes, including urgent coronarography, enables a prompt differentiation between prolonged coronary spasm and atherosclerotic coronary disease, warranting different treatment strategies. Medical treatment with nitrates and calcium channel blockers in most cases prevents recurrence of vasospasms and arrhythmias.

  20. Esclerosis sistémica complicada con síncope y bloqueo AV completo Systemic sclerosis complicated with syncope and complete AV block

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    Francisco Femenía

    2010-10-01

    Full Text Available La esclerosis sistémica es una compleja enfermedad que afecta el tejido conectivo, el sistema vascular y el sistema inmunológico, y se caracteriza por fibrosis cutánea y de órganos viscerales. Los bloqueos de rama y los hemibloqueos se presentan en el 25 a 75% de los casos y constituyen predictores independientes de mortalidad. Los bloqueos auriculoventriculares de segundo o tercer grado son muy raros. Presentamos el caso de una mujer de 47 años de edad, con diagnóstico de esclerosis sistémica, quien presenta episodio sincopal secundario a bloqueo auriculoventricular completo con necesidad de implante de marcapasos definitivo.Systemic sclerosis is a complex disease that affects the connective tissue, the vascular system and the immune system. It typically produces skin and organ fibrosis. Cardiac bundle branch blocks and fascicular blocks occur in 25-75% of the cases and were found to be independent predictors of mortality. Second and third degree atrioventricular block are very rare. We present the case of a 47 year-old female with diagnosis of systemic sclerosis, presented with syncope secondary to complete atrioventricular block requiring permanent pacemaker implantation.

  1. Amphiphilic block copolymer micelles with hydrophobically modified shells

    Czech Academy of Sciences Publication Activity Database

    Jelínek, K.; Uhlík, F.; Limpouchová, Z.; Matějíček, P.; Humpolíčková, J.; Procházka, K.; Tuzar, Zdeněk; Špírková, Milena; Hof, Martin

    2003-01-01

    Roč. 29, 10-11 (2003), s. 655-660 ISSN 0892-7022 R&D Projects: GA AV ČR KSK4050111 Institutional research plan: CEZ:AV0Z4050913 Keywords : micelles * conformation * NRET Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.721, year: 2003

  2. AV nodal reentrant tachycardia with a 2:1 right bundle branch block missed as bidirectional ventricular tachycardia in the first superficial evaluation

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    Akbarzadeh Mohammad Ali

    2017-06-01

    Full Text Available A 95-year old woman was admitted to our emergency unit because of acute abdominal pain. After urgent surgery according to the acute abdomen, she was referred to intensive care unit (ICU of the emergency unit as she was intubated. It was developed a run of new arrhythmia which was diagnosed by cardiology resident as bidirectional ventricular tachycardia due to beat to beat changing the axis of the QRS. However, a second and more precise evaluation of the abnormal ECG suggested a narrow supraventricular tachycardia, most probably AV nodal reentrant tachycardia with a 2:1 right bundle branch block.

  3. Functionalized surfaces of polylactide modified by Langmuir-Blodgett films of amphiphilic block copolymers

    Czech Academy of Sciences Publication Activity Database

    Kubies, Dana; Machová, Luďka; Brynda, Eduard; Lukáš, Jaromír; Rypáček, František

    2003-01-01

    Roč. 14, č. 2 (2003), s. 143-149 ISSN 0957-4530 R&D Projects: GA ČR GA203/99/0576 Institutional research plan: CEZ:AV0Z4050913 Keywords : polylactide * Langmuir - Blodgett films * amphiphilic block copolymers Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.930, year: 2003

  4. AV dissociation, an inevitable response.

    Science.gov (United States)

    Wang, Kyuhyun; Benditt, David G

    2011-07-01

    The independent activation of the atria and ventricles, AV dissociation, is a common phenomenon that occurs during a wide variety of electrophysiologic circumstances. The clinical significance of AV dissociation is often misunderstood. This article examines the basis and clinical implications of AV dissociation. AV dissociation is often an obligatory, secondary phenomenon, and should not be construed as the primary disorder; it may be due to either the AV conduction system being completely blocked (3° AV block) or the P wave and the QRS complex being generated from separate sources (usually, the AV junction or ventricle) but occurring close together during the physiologic refractory period of each other. The latter may happen in junctional or ventricular arrhythmias including escape or accelerated rhythm, tachycardia, or premature beats. The crucial clinical point is not the AV dissociation itself, but that an underlying triggering primary disorder is present and should be identified. ©2011, Wiley Periodicals, Inc.

  5. The properties of batrachotoxin-modified cardiac Na channels, including state-dependent block by tetrodotoxin.

    Science.gov (United States)

    Huang, L Y; Yatani, A; Brown, A M

    1987-09-01

    Batrachotoxin (BTX) modification and tetrodotoxin (TTX) block of BTX-modified Na channels were studied in single cardiac cells of neonatal rats using the whole-cell patch-clamp recording technique. The properties of BTX-modified Na channels in heart are qualitatively similar to those in nerve. However, quantitative differences do exist between the modified channels of these two tissues. In the heart, the shift of the conductance-voltage curve for the modified channel was less pronounced, the maximal activation rate constant, (tau m)max, of modified channels was considerably slower, and the slow inactivation of the BTX-modified cardiac Na channels was only partially abolished. TTX blocked BTX-modified mammalian cardiac Na channels and the block decreased over the potential range of -80 to -40 mV. The apparent dissociation constant of TTX changed from 0.23 microM at -50 mV to 0.69 microM at 0 mV. No further reduction of block was observed at potentials greater than -40 mV. This is the potential range over which gating from closed to open states occurred. These results were explained by assuming that TTX has a higher affinity for closed BTX-modified channels than for open modified channels. Hence, the TTX-binding rate constants are considered to be state dependent rather than voltage dependent. This differs from the voltage dependence of TTX block reported for BTX-modified Na channels from membrane vesicles incorporated into lipid bilayers and from amphibian node of Ranvier.

  6. Comparison of paravertebral and interpleural block in patients undergoing modified radical mastectomy

    Directory of Open Access Journals (Sweden)

    Pankaj Kundra

    2013-01-01

    Conclusion: To conclude, lung functions are well-preserved in patients undergoing modified radical mastectomy under general anesthesia supplemented with paravertebral or IPB. IPB is as effective as PVB for post-operative pain relief. PVB has the added advantage of achieving a more complete block.

  7. A PCBM-Modified TiO2 Blocking Layer towards Efficient Perovskite Solar Cells

    Directory of Open Access Journals (Sweden)

    Gang Lu

    2017-01-01

    Full Text Available Organometal halide perovskite as a promising absorber in solar cells has caught tremendous attention in the past few years. Herein, a hydrophobic PCBM layer was introduced into planar heterojunction perovskite solar cells to form the TiO2/PCBM double blocking layer. The bilayer structure assures the formation of a dense, smooth, and pinhole-free blocking layer. And the PCBM layer can also be in favor of larger grain size perovskite film and further passivate the TiO2 blocking layer. Scanning electron microscope, atomic force microscope, and X-ray diffraction (XRD results suggest the formation of a uniform and compact CH3NH3PbI3−xClx perovskite layer on the PCBM-modified TiO2 blocking layer. The solar cell has reached a PCE up to 16.37%, which is greatly larger than the control device with a PCE of 10.81%.

  8. Dwivedi, AV

    African Journals Online (AJOL)

    Dwivedi, AV. Vol 3, No 2 (2014) - Articles Linguistic realities in Kenya: A preliminary survey. Abstract PDF · Vol 3, No 2 (2014) - Articles Note: Contributors to this Issue Abstract PDF. ISSN: 2026-6596. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  9. Evaluation of tri-steps modified styrene-butadiene-styrene block copolymer membrane for wound dressing

    International Nuclear Information System (INIS)

    Yang, Jen Ming; Huang, Huei Tsz

    2012-01-01

    Tri-steps modified styrene-butadiene-styrene block copolymer (SBS) membrane was prepared with epoxidation, ring opening reaction with maleated ionomer and layer-by-layer assembled polyelectrolyte technique. The tri-steps modified SBS membrane was characterized by infrared spectroscopy and X-ray photoelectron spectroscope (XPS). The structures of the modified SBS membranes were identified with methylene blue and azocarmine G. The content of amino group on the surface of the modified membrane was calculated from uptake of an acid dye. The values of the contact angle, water absorption, water vapor transmission rate and the adsorption of fibronectin on the membranes were determined. To evaluate the biocompatibility of the tri-steps modified SBS membrane, the cytotoxicity, antibacterial and growth profile of the cell culture of 3T3 fibroblasts on the membrane were evaluated. The bactericidal activity was found on the modified SBS. From the cell culture of 3T3 fibroblasts on the membrane, it revealed that the cells not only remained viable but also proliferated on the surface of the tri-steps modified SBS membranes. As the membranes are sterile semipermeable with bactericidal activity and transparent allowing wound checks, they can be considered for shallow wound with low exudates. - Highlights: ► Styrene-butadiene-styrene block copolymer (SBS) was modified with tri-steps. ► The tri-steps are epoxidation, ring opening reaction and layer-by-layer assembly. ► Modified SBS membrane for wound dressing is evaluated. ► Membranes are sterile semipermeable with bactericidal activity and transparent. ► Membranes can be considered for shallow wound with low exudates.

  10. Revalidation of a modified and safe approach of stellate ganglion block

    Directory of Open Access Journals (Sweden)

    Ashok Jadon

    2011-01-01

    Full Text Available Stellate ganglion block (SGB is very effective in management of chronic regional pain syndrome (CRPS-1. However, serious complication may occur due to accidental intravascular (intra-arterial injection of local anaesthetic agents. Abdi and others, has suggested a modified technique in which fluoroscopy-guided block is given at the junction of uncinate process and body of vertebra at C7 level. In this approach vascular structures remain away from the trajectory of needle and thus avoid accidental vascular injection. We have used this technique of SGB in nine patients who were treated for CRPS-I. The blocks were effective in all the patients all the time without any vascular or other serious complication.

  11. Modifying JPEG binary arithmetic codec for exploiting inter/intra-block and DCT coefficient sign redundancies.

    Science.gov (United States)

    Lakhani, Gopal

    2013-04-01

    This article presents four modifications to the JPEG arithmetic coding (JAC) algorithm, a topic not studied well before. It then compares the compression performance of the modified JPEG with JPEG XR, the latest block-based image coding standard. We first show that the bulk of inter/intra-block redundancy, caused due to the use of the block-based approach by JPEG, can be captured by applying efficient prediction coding. We propose the following modifications to JAC to take advantages of our prediction approach. 1) We code a totally different DC difference. 2) JAC tests a DCT coefficient by considering its bits in the increasing order of significance for coding the most significant bit position. It causes plenty of redundancy because JAC always begins with the zeroth bit. We modify this coding order and propose alternations to the JPEG coding procedures. 3) We predict the sign of significant DCT coefficients, a problem is not addressed from the perspective of the JPEG decoder before. 4) We reduce the number of binary tests that JAC codes to mark end-of-block. We provide experimental results for two sets of eight-bit gray images. The first set consists of nine classical test images mostly of size 512 × 512 pixels. The second set consists of 13 images of size 2000 × 3000 pixels or more. Our modifications to JAC obtain extra-ordinary amount of code reduction without adding any kind of losses. More specifically, when we quantize the images using the default quantizers, our modifications reduce the total JAC code size of the images of these two sets by about 8.9 and 10.6%, and the JPEG Huffman code size by about 16.3 and 23.4%, respectively, on the average. Gains are even higher for coarsely quantized images. Finally, we compare the modified JAC with two settings of JPEG XR, one with no block overlapping and the other with the default transform (we denote them by JXR0 and JXR1, respectively). Our results show that for the finest quality rate image coding, the modified

  12. Polystyrene-block-Poly(ionic liquid) Copolymers as Work Function Modifiers in Inverted Organic Photovoltaic Cells.

    Science.gov (United States)

    Park, Jong Baek; Isik, Mehmet; Park, Hea Jung; Jung, In Hwan; Mecerreyes, David; Hwang, Do-Hoon

    2018-02-07

    Interfacial layers play a critical role in building up the Ohmic contact between electrodes and functional layers in organic photovoltaic (OPV) solar cells. These layers are based on either inorganic oxides (ZnO and TiO 2 ) or water-soluble organic polymers such as poly[(9,9-dioctyl-2,7-fluorene)-alt-(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)] and polyethylenimine ethoxylated (PEIE). In this work, we have developed a series of novel poly(ionic liquid) nonconjugated block copolymers for improving the performance of inverted OPV cells by using them as work function modifiers of the indium tin oxide (ITO) cathode. Four nonconjugated polyelectrolytes (n-CPEs) based on polystyrene and imidazolium poly(ionic liquid) (PSImCl) were synthesized by reversible addition-fragmentation chain transfer polymerization. The ratio of hydrophobic/hydrophilic block copolymers was varied depending on the ratio of polystyrene to the PSImCl block. The ionic density, which controls the work function of the electrode by forming an interfacial dipole between the electrode and the block copolymers, was easily tuned by simply changing the PSImCl molar ratio. The inverted OPV device with the ITO/PS 29 -b-PSImCl 60 cathode achieved the best power conversion efficiency (PCE) of 7.55% among the synthesized block copolymers, exhibiting an even higher PCE than that of the reference OPV device with PEIE (7.30%). Furthermore, the surface properties of the block copolymers films were investigated by contact angle measurements to explore the influence of the controlled hydrophobic/hydrophilic characters on the device performances.

  13. Exact solution of corner-modified banded block-Toeplitz eigensystems

    Science.gov (United States)

    Cobanera, Emilio; Alase, Abhijeet; Ortiz, Gerardo; Viola, Lorenza

    2017-05-01

    Motivated by the challenge of seeking a rigorous foundation for the bulk-boundary correspondence for free fermions, we introduce an algorithm for determining exactly the spectrum and a generalized-eigenvector basis of a class of banded block quasi-Toeplitz matrices that we call corner-modified. Corner modifications of otherwise arbitrary banded block-Toeplitz matrices capture the effect of boundary conditions and the associated breakdown of translational invariance. Our algorithm leverages the interplay between a non-standard, projector-based method of kernel determination (physically, a bulk-boundary separation) and families of linear representations of the algebra of matrix Laurent polynomials. Thanks to the fact that these representations act on infinite-dimensional carrier spaces in which translation symmetry is restored, it becomes possible to determine the eigensystem of an auxiliary projected block-Laurent matrix. This results in an analytic eigenvector Ansatz, independent of the system size, which we prove is guaranteed to contain the full solution of the original finite-dimensional problem. The actual solution is then obtained by imposing compatibility with a boundary matrix, whose shape is also independent of system size. As an application, we show analytically that eigenvectors of short-ranged fermionic tight-binding models may display power-law corrections to exponential behavior, and demonstrate the phenomenon for the paradigmatic Majorana chain of Kitaev.

  14. A comparative study of the Louisiana Graduation Exit Exam science scores and student achievement based on block, modified block, and traditional bell schedules

    Science.gov (United States)

    Buczala, Deanna Marie

    The purpose of this study was to investigate the relationships among bell schedules, GEE 21 science scores, and cumulative GPAs. Factors under consideration included teacher perspective, gender, ethnicity and students' at-risk status. The researcher collected data from the Louisiana Department of Education (LDE) targeting seven schools for three types of bell schedules---traditional, modified block, and block. From each school, the cumulative GPAs and GEF 21 science scores of up to 50 randomly selected students were analyzed. The effectiveness of different bells schedules on student achievement has resulted in conflicting data. Some educators feel that block scheduling will provide teachers with more time to engage students in higher-order thinking problems and to better engage them in the content material, thus improving student achievement overall (Gullatt, 2006). Some studies found that block scheduling provides students the opportunity to spend more time examining a subject with greater detail for a longer period of continuous time. Other studies have found that students on traditional schedules outperform block scheduled students on high stakes testing (Veal & Schreiber, 1999). Using a causal-comparative research design, the researcher examined the effect of three different bell schedules on student cumulative GPAS and GEE 21 science scores. The cumulative GPAs for the students were used to determine if there was a difference in the achievement level for students taught using different bell schedules. The GEE 21 science scores were also assessed for possible differences in learning science across various bell schedules.

  15. A new scarless oncoplastic breast-conserving surgery: modified round block technique.

    Science.gov (United States)

    Zaha, Hisamitsu; Onomura, Mai; Unesoko, Mikiko

    2013-12-01

    Round block technique (RBT) is often utilized in breast-conserving surgery, but has problems of late-onset scar widening and changes in the shape or the position of the areola. We have modified RBT (MRBT) to resolve those problems. A circumferential incision was made without excision of the periareolar skin, and subcutaneous dissection was extended to the entire breast. The wound could be widened and moved onto the distant tumor by application of a wound retractor. Partial mastectomy was then performed under direct vision. The wound was easily closed without tension. Forty breast cancer patients were treated with MRBT. The median distance between the nipple and the tumor was 5.2 cm, and the median areolar size was 2.8 cm. Cosmetic results were satisfactory with minimal scar formation. There were neither subsequent changes in the shape nor the position of the areola. MRBT is a useful oncoplastic technique in patients with small areolae, and/or when the tumor location is distant from the nipple. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. A comparative randomized study of paravertebral block versus wound infiltration of bupivacaine in modified radical mastectomy

    Directory of Open Access Journals (Sweden)

    Parul Bansal

    2012-01-01

    Full Text Available Background: Paravertebral block (PVB has the potential to offer long-lasting pain relief because it can uniquely eliminate cortical responses to thoracic dermatomal stimulation. Benefits include a reduction in postoperative nausea and vomiting (PONV, prolonged postoperative pain relief, and potential for ambulatory discharge. Aims: To compare PVB with local infiltration for postoperative analgesia following modified radical mastectomy (MRM. Methods: Forty patients undergoing MRM with axillary dissection were randomly allocated into two groups. Following induction of general anesthesia in group P, a catheter was inserted in the paravertebral space and 0.3 ml/kg of 0.25 % of bupivacaine was administered followed by continuous infusion, while in group L, the surgical incision was infiltrated with 0.3 ml/kg of 0.25 % bupivacaine. Statistical Analysis: The statistical tests were applied as unpaired student ′t′ test/nonparametric test Wilcoxon Mann Whitney test for comparing different parameters such as VAS score and consumption of drugs. The categorical variables such as nausea and vomiting scores, sedation score, and patient satisfaction score were computed by Chi square test/Fisher exact test. Results: VAS score was significantly lower in group P than in group L throughout the postoperative period. The mean alertness score (i.e., less sedation was higher in group P in the postoperative period than group L. The incidence of PONV was less in PVB group. Conclusion: PVB at the end of the surgery results in better postoperative analgesia, lesser incidence of PONV, and better alertness score.

  17. Modified Proofreading PCR for Detection of Point Mutations, Insertions and Deletions Using a ddNTP-Blocked Primer

    Science.gov (United States)

    Chen, Qianqian; Chen, Xiaoxiang; Zhang, Sichao; Lan, Ke; Lu, Jian; Zhang, Chiyu

    2015-01-01

    The development of simple, accurate, rapid and cost-effective technologies for mutation detection is crucial to the early diagnosis and prevention of numerous genetic diseases, pharmacogenetics, and drug resistance. Proofreading PCR (PR-PCR) was developed for mutation detection in 1998 but is rarely applied due to its low efficiency in allele discrimination. Here we developed a modified PR-PCR method using a ddNTP-blocked primer and a mixture of DNA polymerases with and without the 3'-5' proofreading function. The ddNTP-blocked primer exhibited the best blocking efficiency to avoid nonspecific primer extension while the mixture of a tiny amount of high-fidelity DNA polymerase with a routine amount of Taq DNA polymerase provided the best discrimination and amplification effects. The modified PR-PCR method is quite capable of detecting various mutation types, including point mutations and insertions/deletions (indels), and allows discrimination amplification when the mismatch is located within the last eight nucleotides from the 3'-end of the ddNTP-blocked primer. The modified PR-PCR has a sensitivity of 1-5 × 102 copies and a selectivity of 5 × 10-5 mutant among 107 copies of wild-type DNA. It showed a 100% accuracy rate in the detection of P72R germ-line mutation in the TP53 gene among 60 clinical blood samples, and a high potential to detect rifampin-resistant mutations at low frequency in Mycobacterium tuberculosis using an adaptor and a fusion-blocked primer. These results suggest that the modified PR-PCR technique is effective in detection of various mutations or polymorphisms as a simple, sensitive and promising approach. PMID:25915410

  18. Efficient bacterial expression of recombinant potato mop-top virus non-structural triple gene block protein 1 modified by progressive deletion of its N-terminus

    Czech Academy of Sciences Publication Activity Database

    Pečenková, Tamara; Filigarová, Marie; Čeřovská, Noemi

    2005-01-01

    Roč. 41, - (2005), s. 128-135 ISSN 1046-5928 R&D Projects: GA ČR GA522/04/1329 Institutional research plan: CEZ:AV0Z50380511 Keywords : Protein expression * Potato mop-top virus * Triple gene block Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.553, year: 2005

  19. [Selectivity and sensitivity to blocking by hydrogen ions of batrachotoxin-modified sodium channels in nerve fiber membranes].

    Science.gov (United States)

    Mozhaeva, G N; Naumov, A P; Khodorov, B I

    1983-01-01

    Currents through normal and batrachotoxin-modified sodium channels in frog nerve were measured under voltage clamp conditions. Measured reversal potentials and the Goldman equation were used to calculate relative permeabilities. The permeability ratios were: PNa: PNH4: PK = 1: 0.47: 0.19. Hydrogen-to-sodium permeability ratio was estimated from reversal potential measurements in Na-free acid (pH 3.7-3.8) solutions. It was 528 +/- 46 for batrachotoxin-modified sodium channels. Modified channels were less sensitive to hydrogen block as compared with normal ones. The difference in apparent pKa for acid group between normal and modified channels was about 0.40.

  20. Efficacy and complications associated with a modified inferior alveolar nerve block technique. A randomized, triple-blind clinical trial

    Science.gov (United States)

    Montserrat-Bosch, Marta; Nogueira-Magalhães, Pedro; Arnabat-Dominguez, Josep; Valmaseda-Castellón, Eduard; Gay-Escoda, Cosme

    2014-01-01

    Objectives: To compare the efficacy and complication rates of two different techniques for inferior alveolar nerve blocks (IANB). Study Design: A randomized, triple-blind clinical trial comprising 109 patients who required lower third molar removal was performed. In the control group, all patients received an IANB using the conventional Halsted technique, whereas in the experimental group, a modified technique using a more inferior injection point was performed. Results: A total of 100 patients were randomized. The modified technique group showed a significantly higher onset time in the lower lip and chin area, and was frequently associated to a lingual electric discharge sensation. Three failures were recorded, 2 of them in the experimental group. No relevant local or systemic complications were registered. Conclusions: Both IANB techniques used in this trial are suitable for lower third molar removal. However, performing an inferior alveolar nerve block in a more inferior position (modified technique) extends the onset time, does not seem to reduce the risk of intravascular injections and might increase the risk of lingual nerve injuries. Key words:Dental anesthesia, inferior alveolar nerve block, lidocaine, third molar, intravascular injection. PMID:24608204

  1. AVS on satellite

    Science.gov (United States)

    Zhao, Haiwu; Wang, Guozhong; Hou, Gang

    2005-07-01

    AVS is a new digital audio-video coding standard established by China. AVS will be used in digital TV broadcasting and next general optical disk. AVS adopted many digital audio-video coding techniques developed by Chinese company and universities in recent years, it has very low complexity compared to H.264, and AVS will charge very low royalty fee through one-step license including all AVS tools. So AVS is a good and competitive candidate for Chinese DTV and next generation optical disk. In addition, Chinese government has published a plan for satellite TV signal directly to home(DTH) and a telecommunication satellite named as SINO 2 will be launched in 2006. AVS will be also one of the best hopeful candidates of audio-video coding standard on satellite signal transmission.

  2. Spontaneous resolution of complete atrioventricular (A-V ...

    African Journals Online (AJOL)

    Atrioventricular (A-V) disassociation describes the independent beating of the atria and ventricles of the heart. It is not synonymous with complete heart block in the sense that, A-V disassociation is a general term. Heart block describes specific conduction abnormalities that need specific cardiac intervention. This case report ...

  3. Nonlinear state feedback controller design for underactuated mechanical system: a modified block backstepping approach.

    Science.gov (United States)

    Rudra, Shubhobrata; Barai, Ranjit Kumar; Maitra, Madhubanti

    2014-03-01

    This paper presents the formulation of a novel block-backstepping based control algorithm to address the stabilization problem for a generalized nonlinear underactuated mechanical system. For the convenience of compact design, first, the state model of the underactuated system has been converted into the block-strict feedback form. Next, we have incorporated backstepping control action to derive the expression of the control input for the generic nonlinear underactuated system. The proposed block backstepping technique has further been enriched by incorporating an integral action additionally for enhancing the steady state performance of the overall system. Asymptotic stability of the overall system has been analyzed using Lyapunov stability criteria. Subsequently, the stability of the zero dynamics has also been analyzed to ensure the global asymptotic stability of the entire nonlinear system at its desired equilibrium point. The proposed control algorithm has been applied for the stabilization of a benchmarked underactuated mechanical system to verify the effectiveness of the proposed control law in real-time environment. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  4. Thoracic epidural anesthesia and interscalene block for a pneumonectomized patient posted for modified radical mastectomy

    Directory of Open Access Journals (Sweden)

    Mridul Dua

    2017-01-01

    Full Text Available Thoracic epidural anesthesia with ipsilateral brachial plexus block is emerging as an alternative to general anesthesia for oncologic breast surgery.1. A 31 year old, pneumonectomised female with a past history of MDR TB was diagnosed with infiltrating ductal carcinoma in left breast 2 months ago and was posted for MRM. She also had moderate Pulmonary Arterial Hypertension. Thoracic epidural anesthesia was induced with 12 ml of 0.5% Ropivacaine at T6-T7 level. Interscalene block was given with 10 ml 0.5% Ropivacaine using peripheral nerve locator. Patient was comfortable throughout the procedure and remained vitally stable. Post-operative analgesia was given with 10 ml of 0.2% ropivacaine and patient was discharged the following week. Thoracic epidural anesthesia provides the advantage of superior intra and post-operative analgesia without the adverse effects of general anesthesia like postoperative nausea, vomiting, respiratory depression and sedation.2 Coupled with interscalene block for axillary lymph node dissection, it can be successfully used as an alternative to GA for MRM.

  5. Modified Three-Step Search Block Matching Motion Estimation and Weighted Finite Automata based Fractal Video Compression

    Directory of Open Access Journals (Sweden)

    Shailesh Kamble

    2017-08-01

    Full Text Available The major challenge with fractal image/video coding technique is that, it requires more encoding time. Therefore, how to reduce the encoding time is the research component remains in the fractal coding. Block matching motion estimation algorithms are used, to reduce the computations performed in the process of encoding. The objective of the proposed work is to develop an approach for video coding using modified three step search (MTSS block matching algorithm and weighted finite automata (WFA coding with a specific focus on reducing the encoding time. The MTSS block matching algorithm are used for computing motion vectors between the two frames i.e. displacement of pixels and WFA is used for the coding as it behaves like the Fractal Coding (FC. WFA represents an image (frame or motion compensated prediction error based on the idea of fractal that the image has self-similarity in itself. The self-similarity is sought from the symmetry of an image, so the encoding algorithm divides an image into multi-levels of quad-tree segmentations and creates an automaton from the sub-images. The proposed MTSS block matching algorithm is based on the combination of rectangular and hexagonal search pattern and compared with the existing New Three-Step Search (NTSS, Three-Step Search (TSS, and Efficient Three-Step Search (ETSS block matching estimation algorithm. The performance of the proposed MTSS block matching algorithm is evaluated on the basis of performance evaluation parameters i.e. mean absolute difference (MAD and average search points required per frame. Mean of absolute difference (MAD distortion function is used as the block distortion measure (BDM. Finally, developed approaches namely, MTSS and WFA, MTSS and FC, and Plane FC (applied on every frame are compared with each other. The experimentations are carried out on the standard uncompressed video databases, namely, akiyo, bus, mobile, suzie, traffic, football, soccer, ice etc. Developed

  6. Cl II Malocclusion Treatment, Using the Modified Twin Block Appliance Coordinated with Fixed Orthodontics in a Postmenarche Patient

    Directory of Open Access Journals (Sweden)

    Amin Aminian

    2017-01-01

    Full Text Available Functional appliances have been used for treatment of Class II patients for a long time. The main objective of therapy with functional appliances is to induce supplementary lengthening of the mandible by stimulating increased growth at the condylar cartilage. The Twin Block appliance is one of the most commonly used functional appliances. The aim of this paper is to present a case report of mandibular deficiency treatment with Twin Block appliance in a female patient whose sexual maturation (one and a half years after menarche and cervical vertebral maturation stage indicated the end of the growth peak. The treatment started with bonding 0.022 in MBT prescription brackets on the upper arch in order to align upper teeth and create a symmetric overjet. When reaching alignment, a modified Twin Block was given to the patient for 8 months. Final coordination was achieved with fixed appliances in both arches. At the end of the treatment, profile of the patient improved, crowding was relieved, and Cl I relationship with normal overjet and overbite was achieved.

  7. Electron Transfer of Myoglobin Immobilized in Au Electrodes Modified with a RAFT PMMA-Block-PDMAEMA Polymer

    Directory of Open Access Journals (Sweden)

    Carla N. Toledo

    2014-01-01

    Full Text Available Myoglobin was immobilized with poly(methyl methacrylate-block-poly[(2-dimethylaminoethyl methacrylate]PMMA-block-PDMAEMA polymer synthesized by reversible addition-fragmentation chain transfer technique (RAFT. Cyclic voltammograms gave direct and slow quasireversible heterogeneous electron transfer kinetics between Mb-PMMA-block-PDMAEMA modified electrode and the redox center of the protein. The values for electron rate constant (Ks and transfer coefficient (α were 0.055±0.01·s−1 and 0.81±0.08, respectively. The reduction potential determined as a function of temperature (293–328 K revealed a value of reaction center entropy of ΔS0 of 351.3±0.0002 J·mol−1·K−1 and enthalpy change of -76.8±0.1 kJ·mol−1, suggesting solvent effects and charge ionization atmosphere involved in the reaction parallel to hydrophobic interactions with the copolymer. The immobilized protein also exhibits an electrocatalytical response to reduction of hydrogen peroxide, with an apparent Km of 114.7±58.7 μM. The overall results substantiate the design and use of RAFT polymers towards the development of third-generation biosensors.

  8. Utskrift av tredimensionell arkitekturmodell

    OpenAIRE

    Nylund, Johnny

    2015-01-01

    I examensarbetet behandlas modellering av hus anpassade för 3D-skrivning. Uppdragsgivare har varit Purmia Grön, ett företag i Pedersöre som har byggnadsplanering och 3D-modellering som huvudsakliga affärsområde. Målet med examensarbetet var att skapa en modell av ett hus som skulle lämpa sig för 3D-skrivning och inkorporera olika visuella designaspekter. 3D-skrivning är en tillverkningsprocess där ett fysiskt objekt skapas från en digital modell. Metoden har tidigare använts främst av stö...

  9. Skyggedom av enkepensjonsdommen

    DEFF Research Database (Denmark)

    Rognlien, Ida Gundersby

    2014-01-01

    Masteroppgaven undersøker om bortfall av ektefellepensjon ved lovendring med tilbakevirkende kraft er i strid med retten til eiendom etter EMK TP 1 art 1. Skyggedommetoden/ Feminist Judgments -metoden brukes for å gjenskrive enkepensjonsdommen Rt.2006.262 i et feministisk perspektiv. Da mannen døde.......1975.220. I spørsmålet om inngrepet er proporsjonalt ble vektlagt at det ikke foreligger en transparent avveining av de relevante interessene. Videre er hensynene bak og behovene for den opprinnelige ektefellepensjonen fortsatt tilstede, og de er ikke tilstrekkelig avveid mot formålene med inngrepet...

  10. Forenkling av tekniske systemer

    DEFF Research Database (Denmark)

    Førland-Larsen, Arne; Bramslev, Katharina; Halderaker, Ingrid

    De fleste moderne kontorbygg har omfattende tekniske installasjoner. Mange byggeiere opplever at dagens kompliserte tekniske anlegg ikke fungerer som de skal. De ender med å få reklamasjoner, høyt energiforbruk og klager på inneklima. Kan en kraftig forenkling av ventilasjons-, oppvarmings- og...

  11. AV nodal dual pathway electrophysiology and Wenckebach periodicity.

    Science.gov (United States)

    Zhang, Youhua; Mazgalev, Todor N

    2011-11-01

    The precise mechanism(s) governing the phenomenon of AV nodal Wenckebach periodicity is not fully elucidated. Currently 2 hypotheses, the decremental conduction and the Rosenbluethian step-delay, are most frequently used. We have provided new evidence that, in addition, dual pathway (DPW) electrophysiology is directly involved in the manifestation of AV nodal Wenckebach phenomenon. AV nodal cellular action potentials (APs) were recorded from 6 rabbit AV node preparations during standard A1A2 and incremental pacing protocols. His electrogram alternans, a validated index of DPW electrophysiology, was used to monitor fast (FP) and slow (SP) pathway conduction. The data were collected in intact AV nodes, as well as after SP ablation. In all studied hearts the Wenckebach cycle started with FP propagation, followed by transition to SP until its ultimate block. During this process complex cellular APs were observed, with decremental foot formations reflecting the fading FP and second depolarizations produced by the SP. In addition, the AV node cells exhibited a progressive loss in maximal diastolic membrane potential (MDP) due to incomplete repolarization. The pause created with the blocked Wenckebach beat was associated with restoration of MDP and reinitiation of the conduction cycle via the FP wavefront. DPW electrophysiology is dynamically involved in the development of AV nodal Wenckebach periodicity. In the intact AV node, the cycle starts with FP that is progressively weakened and then replaced by SP propagation, until block occurs. AV nodal SP modification did not eliminate Wenckebach periodicity but strongly affected its paradigm. © 2011 Wiley Periodicals, Inc.

  12. The Differential Effects of the Use of Handwriting without Tears® Modified Gray Block Paper to Teach Two Preschool Students with Developmental Delays Capital Letter Writing Skills

    Science.gov (United States)

    Griffith, Jessica; McLaughlin, T. F.; Neyman, Jen; Donica, Denise K.; Robison, Milena

    2013-01-01

    The purpose of this study was to evaluate and measure the effectiveness of Handwriting Without Tears (HWT) modified gray block paper with letter writing on two preschool students diagnosed with developmental delays in pre-academics. Two students were selected from a self-contained special education preschool classroom in the Pacific Northwest. All…

  13. En av gutta

    DEFF Research Database (Denmark)

    Neumann, Cecilie Basberg; Rysst, Mari; Bjerck, Mari

    2012-01-01

    Hvilken betydning har kjønn og klær for kvinner som arbeider i mannsdominerte arbeiderklasseyrker? Forfatterne av denne artikkelen finner at kvinnene må nedtone sitt kjønn og sin seksualitet gjennom å dekke til kroppen, i klær laget for menn, for å signalisere at de er på jobb for å arbeide. Hvor...

  14. Invigning av Orgel Acusticum

    OpenAIRE

    Ericsson, Hans-Ola; Weman Ericsson, Lena; Hannus, Anders

    2012-01-01

    Invigning av Orgel Acusticum, Studio Acusticum, konsertsalenHans-Ola Ericsson, orgel; Lena Weman, traversflöjt; Anders Hannus, klangregi; Birgitta Svendén, konferencièreOlivier Messiaen 1908-1992Apparition de l'Église éternelle (1932)Hans-Ola Ericsson f. 1958Nytt verk (2012) för förstärkt traversflöjt och orgelJohann Sebastian Bach 1685-1750Ich ruf zu dir, Herr Jesu Christ (BWV 639) ur OrgelbüchleinHans-Ola EricssonPostludium - "Spikar" ur orgelmässan "De fyra varelsernas Amen" (1999-2000) fö...

  15. Summer Student Report - AV Workflow

    CERN Document Server

    Abramson, Jessie

    2014-01-01

    The AV Workflow is web application which allows cern users to publish, update and delete videos from cds. During my summer internship I implemented the backend of the new version of the AV Worklow in python using the django framework.

  16. Dynamisk Analys av scrollkompressorn

    OpenAIRE

    Laso Plaza, Elena

    2007-01-01

    Det svenska företaget Thermia använder scrollkompressorer från det amerikanska bolaget Copeland i sina värmepumpsystem. Trots den betydande ljudminskning som scrollkompressorer ger jämfört med andra kompressorer är ljudtrycksnivån fortfarande 56 dBA. Den här ljudtrycksnivån är inte tillräckligt låg om man vill placera systemet i köket. Företaget önskar minska hela systemets ljudtrycksnivå. Rapporten innehåller en dynamisk analys av de olika möjliga ljudkällorna i kompressorn. Den innehåller d...

  17. Teratogene effekter av antiepileptika

    Directory of Open Access Journals (Sweden)

    Bernt A. Engelsen

    2009-10-01

    Full Text Available  SAMMENDRAGCa. 1 av 200 gravide har epilepsi. Gravide med epilepsi har økt risiko for visse obstetriske komplikasjonerog for å føde barn med medfødte misdannelser. Risikoen for misdannelser synes koblet til bruk avantiepileptika under svangerskapet, og ikke til selve epilepsien. Alle typer misdannelser er økt, men leppeganespalteog nevralrørsdefekter utgjør særlig viktige misdannelser. Årsakene til misdannelsene er multifaktorielle.Bruk av antiepileptika i monoterapi kan sies å gi en individuell risiko for større misdannelser påca. 4-6%. Karbamazepin og natriumvalproat gir hhv. 0,5-1% og 2-3% risiko for nevralrørsdefekt. Samletrisiko for større og mindre anomalier inkludert dysmorfe ansiktstrekk synes ikke å overstige 10%. ENGLISH SUMMARYEngelsen BA. Teratogenic effects of antiepileptic drugs. Nor J Epidemiol 1997; 7 (1: 23-28.Approximately 1 in 200 pregnant women have epilepsy, and 1 in 250 births are to children of mothers whouse antiepleptic drugs (AED. Pregnant women with epilepsy have increased risk for certain obstetricalcomplications, and for giving birth to children with congenital malformations. The increased risk forcongenital malformations seems connected to the use of AED, not to the epileptic syndromes. The etiologyof congenital malformations are multifactorial. Use of AED in monotherapy is associated with anindividual risk of giving birth to a child with a major malformation of 4-6%. The specific risk of spinabifida is 0,5 to 1% for carbamazepine and 2-3% for sodium valproate.

  18. Helseeffekter av byluftpartikler

    Directory of Open Access Journals (Sweden)

    Magne Refsnes

    2009-10-01

    Full Text Available Svevestøv i byluft består av forbrenningspartikler og mineralpartikler med svært forskjellige størrelser og kjemiske egenskaper. Svevestøvet kan deles inn i størrelsesfraksjoner som PMAmbient particulate matter (PM comprises particles from different combustion processes and a variety of mineral particles. The particles vary widely in size distribution and chemical/physical characteristics. PM is often divided into size fractions with different aerodynamic diameters: PM10 (PM ! 10 mm, PM2.5 (PM ! 2.5 mm and PM0.1 (PM ! 0.1 mm. Recent population studies have found an association between an increase in mortality and morbidity due to lung and/or cardiovascular disease and short-term increases in PM. The relative risk (RR was approximately 1.005 for an increase in 10 mg/m3 PM10, without an observed threshold even at concentrations below 10 mg/m3. Chronic exposure has been investigated to a lesser extent, but longterm exposure to PM2.5 has been found to be associated with an approximately 10-fold greater increase in RR than short-term exposures. Experimental studies with volunteers in chamber and field studies show mild lung or cardiovascular responses at concentrations of ambient particles (PM2.5/PM10: 100-200 mg/m3 that may occur during episodes of air pollution. Animal studies at higher concentrations have shown stronger responses. The experimental studies support the epidemiological evidence for an adverse health effect of PM. Both population- and experimental studies indicate the existence of vulnerable individuals. At low to average ambient concentrations there seems to exist a discrepancy between the results of population- and experimental studies that might be due to the absence of the most vulnerable individuals in the experimental studies. Together with cell culture experiments, human and animal studies indicate the importance of physical and chemical properties of the particles (size, content of metals, organics, endotoxins, etc. for

  19. "AV nodal" reentry: Part II: AV nodal, AV junctional, or atrionodal reentry?

    NARCIS (Netherlands)

    McGuire, M. A.; Janse, M. J.; Ross, D. L.

    1993-01-01

    The classical model of "atrioventricular (AV) nodal" reentrant tachycardia suggests that the reentrant circuit is entirely within the compact AV node and that AV nodal tissue is present proximal and distal to the circuit. Recent evidence from mapping studies and from examination of the effects of

  20. Læring av erfaring?

    DEFF Research Database (Denmark)

    Ramvi, Ellen

    Hva skal til for å lære av erfaring? Denne avhandlingen er en empirisk baseret undersøkelse av ungdosmskolelæreres muligheter og betingelser for å "lære av erfaring" i den særlige betydning av begrepet  W. Bion gir i sin psykoanalytiske teori. Undersøgelsen baserer seg på et feltarbeid som strekk...... nydefinering av lærerprofesjonalitet, må lærerne gå til kjernen av problemet, nemlig den sårbare lærer-elev relasjonen. Kun da kan det sosiale forsvarssystemet i skolen brytes ned, og den enkelte lærer kan gies rom til å lære av erfaring....

  1. Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA

    Czech Academy of Sciences Publication Activity Database

    Balintová, Jana; Simonova, Anna; Bialek-Pietras, M.; Olejniczak, A.; Lesnikowski, Z. J.; Hocek, Michal

    2017-01-01

    Roč. 27, č. 21 (2017), s. 4786-4788 ISSN 0960-894X R&D Projects: GA ČR GBP206/12/G151 Grant - others:AV ČR(CZ) AP1501 Program:Akademická prémie - Praemium Academiae Institutional support: RVO:61388963 Keywords : nucleotides * nucleoside triphosphates * carboranes * DNA polymerase * oligonucleotides Subject RIV: CC - Organic Chemistry OBOR OECD: Organic chemistry Impact factor: 2.454, year: 2016

  2. Multifunctional alumina/titania hybrid blocking layer modified nanocrystalline titania films as efficient photoanodes in dye sensitized solar cells

    Science.gov (United States)

    Wang, Changlei; Yu, Zhenhua; Bu, Chenghao; Liu, Pei; Bai, Sihang; Liu, Chang; Kondamareddy, Kiran Kumar; Sun, Weiwei; Zhan, Kan; Zhang, Kun; Guo, Shishang; Zhao, Xingzhong

    2015-05-01

    A facile way of fabricating efficient blocking layer on mesoporous TiO2 film of dye-sensitized solar cells (DSSCs) is demonstrated here for the first time. Al2O3 and TiO2 are combined together to form a blocking layer. A simple spin coating technique is employed which is a versatile and low-cost method over the atomic layer deposition (ALD) technique. Multifunctional alumina/titania (Al2O3/TiO2) hybrid overlayer is prepared on traditional TiO2 nanocrystalline thin film surface, through sequential deposition of AlCl3·6H2O and TiCl4 precursor solutions followed by sintering at 500 °C for 30 min. Al2O3 effectively plays its role in retarding interfacial recombination of electrons and improving open circuit potential (Voc), while the tiny TiO2 clusters synthesized from TiCl4 treatment act as electron transporting channels to facilitate electron diffusion which leads to enhanced photocurrent (Jsc). Compared to the device without blocking layer, the DSSCs assembled with Al2O3/TiO2 hybrid blocking layer showed improvement in Jsc (from 13.09 mA/cm2 to 16.90 mA/cm2) as well as in Voc (from 0.72 V to 0.73 V) resulting a much better conversion efficiency of 8.60%.

  3. Lokalisering av arbeidsplasser og boliger

    DEFF Research Database (Denmark)

    Næss, Petter

    2011-01-01

    En miljømessig effektiv lokalisering av arbeidsplasser og boliger sikter mot å begrense - og helst redusere - biltrafikk og miljøproblemer knyttet til bytransport, sammenliknet med alternative lokaliseringer. En effektiv transportmessig lokalisering kan også bidra til å redusere tap av verdifulle...... arealer (f eks jordbruksareal eller natur- og friluftsområder) utenfor dagens tettstedsgrense. Tiltaket må samtidig utformes slik at en kan bevare viktige bomiljøkvaliteter og så mye som mulig av de grønne arealene innenfor tettbebyggelsen....

  4. Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

    Science.gov (United States)

    Balintová, Jana; Simonova, Anna; Białek-Pietras, Magdalena; Olejniczak, Agnieszka; Lesnikowski, Zbigniew J; Hocek, Michal

    2017-11-01

    5-[(p-Carborane-2-yl)ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. "AV nodal" reentry: Part I: "AV nodal" reentry revisited

    NARCIS (Netherlands)

    Janse, M. J.; Anderson, R. H.; McGuire, M. A.; Ho, S. Y.

    1993-01-01

    This review is the first of a two-part series of articles on "atrioventricular [AV] nodal reentry." The early clinical literature as well as the experimental studies are reviewed, and more recent morphologic data are presented, with the aim of clarifying whether the reentrant circuit is confined to

  6. Objektiv kumulasjon av voldgiftsregulerte krav

    OpenAIRE

    Jacobsen, Andreas Skjevik

    2013-01-01

    Oppgaven omhandler adgangen til objektiv kumulasjon etter tvl. § 15-1 når ett eller flere krav er regulert av voldgiftsavtale, jf. vogl. §§ 9 og 10. En voldgiftsavtale reiser flere spørsmål i tilknytning til objektiv kumulasjon for domstolene. For det første må det tas stilling til den prinsipielle stillingen til voldgiftsregulerte krav ved domstolene. For det andre reiser objektiv kumulasjon særlige tolkningsspørsmål ved tolkningen av voldgiftsavtalen. Oppgavens kjerne er dermed å redegjøre ...

  7. Regulering av termineringspriser i telebransjen

    OpenAIRE

    Lilloe-Olsen, Espen

    2010-01-01

    Denne oppgaven analyserer konkurranse mellom mobile nettverk i telebransjen. Formålet med oppgaven er å gi en samlet gjennomgang av litteraturen både om hvorfor termineringspriser burde reguleres på dagens måte basert på langsiktige merkostnader (LRIC), og på en alternativ måte kalt 'bill-and-keep'. Det vil argumenteres for at regulering av termineringspriser basert på langsiktige merkostnader vil føre til et ineffektivt høyt prisnivå, og bidra til å forsterke ...

  8. [Effect of modified huanglian wendan decoction in treating senile patients with mild cognitive impairment of turbid-phlegm blocking orifice syndrome].

    Science.gov (United States)

    Guo, Ren-zhen; Zhou, Wen-quan; Luo, Zeng-gang

    2010-01-01

    To observe the clinical efficacy of modified Huanglian Wendan Decoction (HWD) in treating senile mild cognitive impairment (MCI) of turbid-phlegm blocking orifice syndrome. With a block randomized, double-blinded and controlled design adopted, the 64 patients of MCI selected from December 2007 to February 2009 were randomly and equally assigned to two groups. The treatment group was treated with HWD in dose of 200 mL, twice a day; the control group was given Aniracetam 0.2 g (for patients over 70-years-old, 0.1 g) three times a day. And the illusive medicine in dosage-form of capsule/decoction simulated to that used in the opposite group was applied. The medication and observation lasted for three months. Chinese medicine syndrome, cognition capacity (by MMSE), laboratory indexes [acetylcholine (Ach), superoxide dismutase (SOD), malondialdehyde (MDA)] and safety related indexes in patients were observed. After treatment, MMSE score increased in both groups, but the increment in the treatment group was significantly higher than that in the control group (PAniracetam; and with effects for raising SOD activity and reducing MDA level similar to those of Aniracetam.

  9. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs.

    Science.gov (United States)

    Bähr, Andrea; Käser, Tobias; Kemter, Elisabeth; Gerner, Wilhelm; Kurome, Mayuko; Baars, Wiebke; Herbach, Nadja; Witter, Kirsti; Wünsch, Annegret; Talker, Stephanie C; Kessler, Barbara; Nagashima, Hiroshi; Saalmüller, Armin; Schwinzer, Reinhard; Wolf, Eckhard; Klymiuk, Nikolai

    2016-01-01

    We have successfully established and characterized a genetically modified pig line with ubiquitous expression of LEA29Y, a human CTLA4-Ig derivate. LEA29Y binds human B7.1/CD80 and B7.2/CD86 with high affinity and is thus a potent inhibitor of T cell co-stimulation via this pathway. We have characterized the expression pattern and the biological function of the transgene as well as its impact on the porcine immune system and have evaluated the potential of these transgenic pigs to propagate via assisted breeding methods. The analysis of LEA29Y expression in serum and multiple organs of CAG-LEA transgenic pigs revealed that these animals produce a biologically active transgenic product at a considerable level. They present with an immune system affected by transgene expression, but can be maintained until sexual maturity and propagated by assisted reproduction techniques. Based on previous experience with pancreatic islets expressing LEA29Y, tissues from CAG-LEA29Y transgenic pigs should be protected against rejection by human T cells. Furthermore, their immune-compromised phenotype makes CAG-LEA29Y transgenic pigs an interesting large animal model for testing human cell therapies and will provide an important tool for further clarifying the LEA29Y mode of action.

  10. Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer

    Science.gov (United States)

    Tang, Xiaolong; Dai, Jingjing; Xie, Jun; Zhu, Yongqiang; Zhu, Ming; Wang, Zhi; Xie, Chunmei; Yao, Aixia; Liu, Tingting; Wang, Xiaoyu; Chen, Li; Jiang, Qinglin; Wang, Shulei; Liang, Yong; Xu, Congjing

    2015-06-01

    Fungal infections are an important cause of morbidity and mortality in immunocompromised patients. Amphotericin B (AMB), with broad-spectrum antifungal activity, has long been recognized as a powerful fungicidal drug, but its clinical toxicities mainly nephrotoxicity and poor solubility limit its wide application in clinical practice. The fungal metabolism along with the host immune response usually generates acidity at sites of infection, resulting in loss of AMB activity in a pH-dependent manner. Herein, we developed pH-responsive AMB-loaded and surface charge-switching poly( d, l-lactic- co-glycolic acid)- b-poly( l-histidine)- b-poly(ethylene glycol) (PLGA-PLH-PEG) nanoparticles for resolving the localized acidity problem and enhance the antifungal efficacy of AMB. Moreover, we modified AMB-encapsulated PLGA-PLH-PEG nanoparticles with anti- Candida albicans antibody (CDA) (CDA-AMB-NPs) to increase the targetability. Then, CDA-AMB-NPs were characterized in terms of physical characteristics, in vitro drug release, stability, drug encapsulation efficiency, and toxicity. Finally, the targetability and antifungal activity of CDA-AMB-NPs were investigated in vitro /in vivo. The result demonstrated that CDA-AMB-NPs significantly improve the targetability and bioavailability of AMB and thus improve its antifungal activity and reduce its toxicity. These NPs may become a good drug carrier for antifungal treatment.

  11. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs

    Science.gov (United States)

    Bähr, Andrea; Käser, Tobias; Kemter, Elisabeth; Gerner, Wilhelm; Kurome, Mayuko; Baars, Wiebke; Herbach, Nadja; Witter, Kirsti; Wünsch, Annegret; Talker, Stephanie C.; Kessler, Barbara; Nagashima, Hiroshi; Saalmüller, Armin; Schwinzer, Reinhard; Wolf, Eckhard; Klymiuk, Nikolai

    2016-01-01

    We have successfully established and characterized a genetically modified pig line with ubiquitous expression of LEA29Y, a human CTLA4-Ig derivate. LEA29Y binds human B7.1/CD80 and B7.2/CD86 with high affinity and is thus a potent inhibitor of T cell co-stimulation via this pathway. We have characterized the expression pattern and the biological function of the transgene as well as its impact on the porcine immune system and have evaluated the potential of these transgenic pigs to propagate via assisted breeding methods. The analysis of LEA29Y expression in serum and multiple organs of CAG-LEA transgenic pigs revealed that these animals produce a biologically active transgenic product at a considerable level. They present with an immune system affected by transgene expression, but can be maintained until sexual maturity and propagated by assisted reproduction techniques. Based on previous experience with pancreatic islets expressing LEA29Y, tissues from CAG-LEA29Y transgenic pigs should be protected against rejection by human T cells. Furthermore, their immune-compromised phenotype makes CAG-LEA29Y transgenic pigs an interesting large animal model for testing human cell therapies and will provide an important tool for further clarifying the LEA29Y mode of action. PMID:27175998

  12. Bruk av kartleggingsresultater i forbedringsarbeid

    DEFF Research Database (Denmark)

    Nordahl, Thomas; Hansen, Line Skov

    . Barnehagen har gjerne tilgang på informasjon fra kartlegginger, men det er ikke alltid denne informasjonen blir systematisk analysert og aktivt brukt i forbedringsarbeid. Forfatterne viser hvordan slike analyser kan gjennomføres på forskjellige nivåer i den enkelte barnehage, og vektlegger viktigheten av...

  13. A tannin-blocking agent does not modify the preference of sheep towards tannin-containing plants.

    Science.gov (United States)

    Hernández-Orduño, G; Torres-Acosta, J F J; Sandoval-Castro, C A; Capetillo-Leal, C M; Aguilar-Caballero, A J; Alonso-Díaz, M A

    2015-06-01

    Sheep have been suggested to use their senses to perceive plant properties and associate their intake with consequences after ingestion. However, sheep with browsing experience do not seem to select against tannin-rich browsing materials in cafeteria trials. Thus, the objective of the present study was to evaluate the relationship between the chemical composition, selectivity index (SI), preference and intake rate (IR) of tannin-containing forage trees offered to sheep in cafeteria experiments. Four trees were selected for their condensed tannin content and their varying biological activities. Havardia albicans (high biological activity), Leucaena leucocephala (medium biological activity), Acacia gaumeri (low biological activity) and Brosimum alicastrum (very low biological activity) were used in this study. Ten hair sheep (23.7kg±1.43LW) with eight months of browsing experience in native vegetation were used in this study. Polyethylene glycol (PEG 3600MW) was administered to five sheep during all experiments. In experiment 1, fresh foliage from all trees was offered ad libitum for 4h. In experiment 2, B. alicastrum was withdrawn and the preference was determined again. The forage preference in experiment 1 was A. gaumeri (14.77gDM/kgLW)>B. alicastrum (11.77gDM/kgLW)>H. albicans (3.71gDM/kgLW)=L. leucocephala (1.87gDM/kgLW) (PH. albicans=L. leucocephala. PEG administration had no effect on the preference or IR. The intake rate seemed to have been affected by the plant density. Moreover, fiber compounds were found to be better predictors of DM intake than polyphenolic compounds at levels typically found in the evaluated forages. It was concluded that tannins and PEG did not modify the preferences of sheep in cafeteria trials. Thus, tannins are not involved in the preference regulation of animals with browsing experience. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Bruk av RPAS til kartlegging av avdekket fjell

    OpenAIRE

    Arnesen, Jonas Gjersaas

    2014-01-01

    NORSK: Denne bacheloroppgaven omhandler Remotely Piloted Aircraft Systems (RPAS) og ønsker å finne svar på om dette er et verktøy som kan benyttes til kartlegging av avdekket fjell – ”Use of RPAS for surveying revealed rocks”. Kartlegging med RPAS har mange likhetstrekk med tradisjonell flyfotografering fra fly og helikopter, og det er flybilder som er utgangspunktet for å generere de triangulerte terrengmodellene. Resultatene fra RPAS-flygningen vil bli sammenliknet med refera...

  15. Minimizing ventricular pacing by a novel atrioventricular (AV) delay hysteresis algorithm in patients with intact or compromised intrinsic AV conduction and different atrial and ventricular lead locations.

    Science.gov (United States)

    Pakarinen, Sami; Toivonen, Lauri

    2013-09-01

    To investigate if an advanced AV search hysteresis (AVSH) algorithm, Ventricular Intrinsic Preference (VIP(™)), reduces the incidence of ventricular pacing (VP) in sinus node dysfunction (SND) with both intact and compromised AV conduction and with intermittent AV block regardless of the lead positions in the right atria and the ventricle. Patients were classified as having intact AV (AVi) conduction if the PR interval was ≤ 210 ms on ECG and 1:1 AV conduction during atrial pacing up to 120 bpm with PR interval ≤ 350 ms. Otherwise the AV conduction was classified as compromised (AVc). Both AVi and AVc patients were randomized to VIP ON or OFF. VIP performed an intrinsic AV conduction search every 30 s for three consecutive atrial cycles with the extension of the sensed and paced AV (SAV/PAV) delays from basic values of 150/200 ms to 300/350 ms. Extended AV intervals were allowed for three cycles when VP occurred before returning to basic AV delays. The primary end-point was %VP at 12 months. Among 389 patients, 30.1% had intact and 69.9% had compromised AV conduction. The mean %VP at 12 months was 9.6% by VIP compared to 51.8% with standard AV settings in patients with AVi (P < 0.0001) and 28.0% versus 78.9% (P < 0.0001) with AVc. With VIP, excessive %VP among most used lead positions was not seen. Conversely, when VIP was off %VP was low only in patients who had leads in the RA septal-RV septal position (23.0%). VIP feature reduces VP both in patients with SND and with intermittent heart block regardless of the lead positions in the right atria and the ventricle.

  16. Forebygging av trykksår

    OpenAIRE

    Norderhaug, Inger Natvig; Lauvrak, Vigdis; Juvet, Lene Kristine

    2010-01-01

    NORSK: Bakgrunn En nasjonal pasientsikkerhetskampanje, med planlagt oppstart i 2011, er under forberedelse. For å støtte beslutningsprosessen rundt valg av innsatsområder og tiltak, har vi foretatt en hurtigoppsummering av kunnskapsgrunnlaget om effekt av et utvalg av tiltak for å forebygge trykksår hos pasienter i sykehjem og sykehus. Oppdrag Oppdraget ble gitt av Nasjonalt kunnskapssenter for helsetjenesten, sekretariatet for pasientsikkerhetskampanjen 2011. Hovedkonklusjoner ...

  17. PREPARATION FOR RETIREMENT - AVS SEMINAR

    CERN Multimedia

    Social Service

    2001-01-01

    The 500 or so participants in the fifth Preparation for Retirement seminar held at the end of March were unfortunately deprived of the planned session on the AVS due to the unavailability of the Director of the Caisse Cantonale Genevoise de Compensation (CCGC). We have since had formal confirmation that because of an extra workload due to important changes in the Swiss tax and social legislation and the implementation this summer of the maternity insurance in Geneva, the CCGC has suspended its participation in preparation for retirement seminars in the international organisations for the time being. Conscious of the necessity of offering a session dedicated to the AVS, it is with pleasure that we can inform you that one of our legal advisers, Mr Lorenz Stampfli, has accepted to lead this session. In order to allow for adequate preparation we have reserved the following date: Wednesday 26 September from 14.00 to 16.00 in the Main Amphitheatre The session will be open to all people already registered and any o...

  18. SANS study of coated block copolymer micelles

    Czech Academy of Sciences Publication Activity Database

    Pleštil, Josef; Kříž, Jaroslav; Koňák, Čestmír; Pospíšil, Herman; Kadlec, Petr; Sedláková, Zdeňka; Grillo, I.; Cubitt, R.

    2005-01-01

    Roč. 206, č. 12 (2005), s. 1206-1215 ISSN 1022-1352 R&D Projects: GA ČR GA203/03/0600; GA AV ČR IAA1050201; GA AV ČR KSK4050111 Institutional research plan: CEZ:AV0Z40500505 Keywords : block copolymer micelles * core-shell polymers * nanoparticles Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.111, year: 2005

  19. Kritik av den negativa uppbyggligheten

    DEFF Research Database (Denmark)

    Stjernfelt, Frederik; Thomsen, Søren Ulrik

    Under efterkrigstiden har ett märkligt fenomen fått fäste i kulturen. Ett konstverk, en handling, en utsaga bedöms inte längre efter om de är sköna, goda och sanna, utan efter om de bryter mot regler, gör uppror mot det konventionella eller angriper etablerade tänkesätt. Överskridandet av normer...... och provokationen mot inrotade uppfattningar framställs som viktigare än de positiva resultaten, avståndstagandet viktigare än ställningstagandet. Från att ha varit idéer hos ett fåtal filosofer, konstnärer och bohemer har denna negativism efterhand blivit en ideologi för den breda massan. Den...

  20. Supra-Hisian Conduction Block as an Unusual Presenting Feature of Takotsubo Cardiomyopathy.

    Science.gov (United States)

    Prabhu, Mukund Aravind; Pai, Praveen Gopalakrishna; Vupputuri, Anjith; Shekhar, Saritha; Harikrishnan, Madhavankutty Santhakumari; Kumaraswamy, Natarajan Umayammal

    2017-05-01

    Atrioventricular (AV) block is rare in Takotsubo cardiomyopathy (TC). A 66-year-old female presented with fatigue. Her electrocardiogram revealed 3:2 Mobitz Type II AV block, confirmed to be supra-Hisian by electrophysiological study. Echocardiogram and left ventricular angiogram showed moderate left ventricular dysfunction and apical ballooning, whereas coronary angiogram revealed mildly ectatic coronaries. At 2 weeks AV block persisted, needing permanent pacemaker implantation. At 1-month follow-up, she had normal ventricular function and no AV block. Delayed recovery of AV conduction is possible in TC, thus implying to wait for a longer period before implanting a pacemaker. © 2016 Wiley Periodicals, Inc.

  1. The analgesic efficacy of ultrasound-guided modified rectus sheath block compared with wound infiltration in reduction of postoperative morphine consumption in women undergoing open hysterectomy or myomectomy: A randomized controlled trial 14/09/2012 trial

    OpenAIRE

    Mukesh Kumar Shah; Sandeep S Kulkarni; Wendy Fun

    2012-01-01

    Introduction: As ultrasound allows more accurate placement of local anesthetic (LA), ultrasound-guided modified rectus sheath block (MRSB) was compared with wound infiltration (WI) in women having open hysterectomy or myomectomy for fibroids via a Pfannenstiel incision under general anesthesia. Materials and Methods: Forty-two American Society of Anesthesiologists Class ASA I,II and III patients were recruited into two groups in a randomized patient-blinded controlled trial excluding thos...

  2. Arvelig hemokromatose - nytten av screening

    Directory of Open Access Journals (Sweden)

    Arne Åsberg

    2009-10-01

    Full Text Available Arvelig hemokromatose fører til jernopphopning i kroppen, men gir sjelden alvorlig helseskade. Nesten alle hemokromatosepasienter i vårt land er homozygote for C282Y-mutasjonen i HFE-genet. Omtrent 7 per 1000 innbyggere har denne genotypen. Alvorlig syke blir bare omkring 5-15% av homozygote menn og nesten ingen kvinner. Likevel er det holdepunkter for at screening for hemokromatose blant friske, yngre menn kan være kostnadseffektivt. Det er relativt lett å påvise om en person er disponert for sykdommen, i god tid før den bryter ut, og forebyggende behandling er billig og effektiv. Imidlertid kan vi ikke forutsi hvilke screeningpositive personer som ubehandlet får alvorlig sykdom. Et kontrollert forsøk med screening bør gjennomføresHereditary hemochromatosis – benefits of screening. Hereditary hemochromatosis leads to iron accumulation in the body; however, serious illness due to hemochromatosis is rare. In Norway, almost all patients with hemochromatosis are homozygous for the C282Ymutation in the HFE-gene, a genotype carried by about 7 per 1000 inhabitants. Serious complications are seen in only about 5-15% of homozygous men and in very few women. Nevertheless, screening young men for hemochromatosis may be cost-effective. Detecting predisposed men is relatively straightforward, and prophylactic treatment is cheap and effective. However, we can not predict, among screen-positive men, the few who untreated will become seriously ill. A controlled screening trial should be conducted.

  3. Frequency-dependent electrophysiological remodeling of the AV node by hydroalcohol extract of Crocus sativus L. (saffron) during experimental atrial fibrillation: the role of endogenous nitric oxide.

    Science.gov (United States)

    Khori, Vahid; Alizadeh, Ali Mohammad; Yazdi, Hamidreza; Rakhshan, Elnaz; Mirabbasi, Abbas; Changizi, Shima; Mazandarani, Masumeh; Nayebpour, Mohsen

    2012-06-01

    The study assessed the hydroalcohol extract effects of Crocus sativus L. (saffron) on (i) the basic and rate-dependent electrophysiological properties of the AV node, (ii) remodeling of the AV node during experimental atrial fibrillation (AF) and (iii) the role of nitric oxide (NO) in the effects of saffron on the AV node. Stimulation protocols in isolated AV node were used to quantify AV nodal recovery, facilitation and fatigue in four groups of rabbits (n = 8-16 per group). In addition, the nodal response to AF was evaluated at multiple cycle lengths and during AF. Saffron had a depressant effect on AV nodal rate-dependent properties; further, it increased Wenckebach block cycle length, functional refractory period, facilitation and fatigue (p AV node (p AV node during AF by saffron. Saffron increased the AV nodal refractoriness and zone of concealment. These depressant effects of saffron were mediated by endogenous NO. Copyright © 2011 John Wiley & Sons, Ltd.

  4. Förpackning av keramiska substrat

    OpenAIRE

    Karlsson, Jan

    2008-01-01

    Detta examensarbete handlar om forpackning av keramiska substrat. Canning ar det universella namnet pa forpackning av keramiska substrat. Keramiska substrat kan vara katalysatorer eller partikelfilter som anvands som ett efterbehandlingssystem i bensin och Diesel applikationer. Examensarbetet genomfordes hos Scania CV AB. I installationsprocessen sveps en keramisk fibermatta runt det keramiska substratet. Substratet inkapslas sedan med ett metalholje. Rapporten inleds med att beskriva olika i...

  5. Reliabilitet av den norske versjonen av Timed Up and Go (TUG)

    OpenAIRE

    Botolfsen, Pernille; Helbostad, Jorunn L.

    2010-01-01

    Hensikt: Vurdere intratester-, intertester-, og test-retest reliabilitet av den norske versjonen av «Timed Up and Go» (TUG). Design: Metodestudie som benytter tverrsnittsstudie-design. Materiale og metode: Tretti personer (20 kvinner og 10 menn) over 75 år (gjennomsnitt 82,5) gjennomførte TUG tre ganger. To fysioterapeuter skåret deltagerne. For utregning av relativ reliabilitet ble intraclass correlation coefficient (ICC) anvendt, og for utregning av absolutt reliabilitet b...

  6. Situasjonsbestemt ledelse av studentgrupper i friluftsliv

    Directory of Open Access Journals (Sweden)

    Odd Lennart Vikene

    2014-05-01

    Full Text Available Artikkelen gir et praktisk eksempel på hvordan ulike studentgrupper i forbindelse med bygging av nødbivuakk i vinterfjellet opplevde min situasjonsbestemte ledelse som veileder. Teorigrunnlaget viser til situasjonsbestemte ledelsesmodeller og hva som kjennetegner god veiledning i friluftsliv. Datainnsamlingen bygger på kvantitative data fra et spørreskjema og benyttes til å analysere studentenes opplevelse av veileders ledelse ut i fra rangeringsmetoden Visuell Analog Skala (VAS. Fra samme spørreskjema var det også et åpent spørsmål som benyttes til refleksjon over studentenes opplevelse av sikkerhet i undervisningssituasjonen. Resultatene viser at studentgruppene opplevde klare ledelsesforskjeller gjennom de ulike fasene som ledelsen ble delt opp i, men at ledelsesatferden varierte lite i forhold til gruppenes erfaringsgrunnlag. Resultatene tyder på at jeg som veileder i stor grad har blitt påvirket av mine tidligere erfaringer og den potensielle risikoen som ligger ved aktiviteten. Selv om den situasjonsbestemte ledelsen varierte lite mellom de tre gruppene, viser resultatenes store standardavvik at de ulike smågruppene opplevde at ledelsen varierte. Dette tyder på at jeg som veileder til en viss grad har evnet å benytte situasjonsbestemt ledelse i praksis. På grunn av studentgruppenes relativt like oppfatning av ledelsen i de ulike fasene, viser resultatene også noe av vanskelighetene veileder har i forhold til å gjøre en korrekt vurdering av gruppens evner og erfaring i relasjon til læringssituasjonene som oppstår. Sentralt for ledelsen er likevel at studentgruppene opplevde ledelsen som betryggende, noe som gir studentene et godt grunnlag for senere opplevelser i tilknytning til vinterfriluftsliv og bygging av nødbivuakk.

  7. Uptake of AV-1451 in meningiomas.

    Science.gov (United States)

    Bruinsma, Tyler J; Johnson, Derek R; Fang, Ping; Senjem, Matthew; Josephs, Keith A; Whitwell, Jennifer L; Boeve, Bradley F; Pandey, Mukesh K; Kantarci, Kejal; Jones, David T; Vemuri, Prashanthi; Murray, Melissa; Graff-Radford, Jonathan; Schwarz, Christopher G; Knopman, David S; Petersen, Ronald C; Jack, Clifford R; Lowe, Val J

    2017-12-01

    AV-1451 is an imaging agent labeled with the positron-emitting radiolabel Fluorine-18. 18F-AV-1451 binds paired helical filament tau (PHF-tau), a pathology related to Alzheimer's disease. In our study of AV-1451 uptake in the brains of cognitively normal subjects, we noted a case of a meningioma with visually significant uptake of AV-1451. We initiated the present retrospective study to further examine cases of meningioma that underwent AV-1451 imaging. We searched the patient records of 650 patients who had undergone AV-1451 at our institution for the keyword "meningioma" to identify potential cases. PET/CT and MRI results were visually reviewed and semi-quantitative analysis of PET was performed. A paired student's t test was run between background and tumor standard uptake values. Fisher's exact test was used to examine the association between AV-1451 uptake and presence of calcifications on CT. We identified 12 cases of meningioma, 58% (7/12) of which demonstrated uptake greater than background using both visual analysis and tumor-to-normal cortex ratios (T/N + 1.90 ± 0.83). The paired student's t test revealed no statistically significant difference between background and tumor standard uptake values (p = 0.09); however, cases with a T/N ratio greater than one showed statistically higher uptake in tumor tissue (p = 0.01). A significant association was noted between AV-1451 uptake and presence of calcifications (p = 0.01). AV-1451 PET imaging should be reviewed concurrently with anatomic imaging to prevent misleading interpretations of PHF-tau distribution due to meningiomas.

  8. Nedbrytning av utvalgte plantevernmidler i norsk jordsmonn

    OpenAIRE

    Haneborg, Mads Alexander

    2015-01-01

    Denne masteroppgaven har hatt som formål å modellere nedbrytningen av et utvalg sprøytemidler som ble testet på to norske forsøksfelt, i Stjørdal og Klepp med ulike klimatiske forhold og jordsmonn. For begge forsøksfelt ble det foretatt uttak av jordprøver over en periode på ett år fra sprøytingen, i tidsrommet fra mai 2012 til juni 2013. Jordprøvene ble analysert ved bruk av LC-MS/MS etter prøveopparbeiding med væskeekstraksjon. Intern standard metode ble benyttet til kvantifise...

  9. AVS (Application Visualization System) user's guide

    International Nuclear Information System (INIS)

    Masuko, Kenji; Kato, Katsumi; Gorai, Kazuo; Yamazaki, Kazuhiko.

    1996-03-01

    Computer and network environment for image processing has been developed and maintained under the course of establishing a distributed processing environment by the information system operating division. We introduced a server for image processing, AVS for image processing software and an animation processing system (video, frame scan converter). This report summarizes the information to use AVS and to develop and maintain computer and network environment for image processing. (author)

  10. Resuscitation great. Karel Wenckebach: the story behind the block.

    Science.gov (United States)

    Mendoza-Davila, Natalia; Varon, Joseph

    2008-11-01

    The first documentation of a human atrioventricular (AV) block dates back to 1873, when A.L. Galabin reported a 34-year-old patient using an apexcardiogram. This was followed the same year by Luciani, recording 2nd degree AV blocks while studying frogs. In 1899, Karel F. Wenckebach provided the cardiology field with the criteria of what he called "Luciani periods", what we now know as Wenckebach Periodicity or Mobitz I AV block. The classic electrocardiographic presentation of Mobitz I/Wenckebach periodicity is characterized by progressive prolongation of the PR interval on the electrocardiogram (EKG) on consecutive beats followed by a blocked P wave. This clinical entity is the first and most common of two types of 2nd degree AV block. This manuscript reviews the life of Karel F. Wenckebach and the events that led this great Dutch physician to make one of the most important contributions to the field of cardiology.

  11. Population Blocks.

    Science.gov (United States)

    Smith, Martin H.

    1992-01-01

    Describes an educational game called "Population Blocks" that is designed to illustrate the concept of exponential growth of the human population and some potential effects of overpopulation. The game material consists of wooden blocks; 18 blocks are painted green (representing land), 7 are painted blue (representing water); and the remaining…

  12. Nodal recovery, dual pathway physiology, and concealed conduction determine complex AV dynamics in human atrial tachyarrhythmias.

    Science.gov (United States)

    Masè, Michela; Glass, Leon; Disertori, Marcello; Ravelli, Flavia

    2012-11-15

    The genesis of complex ventricular rhythms during atrial tachyarrhythmias in humans is not fully understood. To clarify the dynamics of atrioventricular (AV) conduction in response to a regular high-rate atrial activation, 29 episodes of spontaneous or pacing-induced atrial flutter (AFL), covering a wide range of atrial rates (cycle lengths from 145 to 270 ms), were analyzed in 10 patients. AV patterns were identified by applying firing sequence and surrogate data analysis to atrial and ventricular activation series, whereas modular simulation with a difference-equation AV node model was used to correlate the patterns with specific nodal properties. AV node response at high atrial rate was characterized by 1) AV patterns of decreasing conduction ratios at the shortening of atrial cycle length (from 236.3 ± 32.4 to 172.6 ± 17.8 ms) according to a Farey sequence ordering (conduction ratio from 0.34 ± 0.12 to 0.23 ± 0.06; P AV block patterns occurring during regular atrial tachyarrhythmias. The characterization of AV nodal function during different AFL forms constitutes an intermediate step toward the understanding of complex ventricular rhythms during atrial fibrillation.

  13. Occult etiologies of complete atrioventricular block: Report of two cases

    Directory of Open Access Journals (Sweden)

    Neeta Bachani

    2016-09-01

    Full Text Available In patients presenting with complete atrioventricular (AV block, the common causes are degeneration of the conduction system, acute myocardial infarction, congenital and metabolic disorders (such as azotemia. However, at times, no cause can be ascribed and the label congenital or degenerative is applied depending on the patient's age and the QRS complex width. We present two cases of patients with complete AV block, who were subsequently found to have rare etiologies – sarcoidosis (with isolated feature of AV block and non-Hodgkin's lymphoma.

  14. Outcomes of AV Fistulas and AV Grafts after Interventional Stent-Graft Deployment in Haemodialysis Patients.

    Science.gov (United States)

    Schmelter, Christopher; Raab, Udo; Lazarus, Friedrich; Ruppert, Volker; Vorwerk, Dierk

    2015-08-01

    The study was designed to assess outcomes of arteriovenous (AV) accesses after interventional stent-graft deployment in haemodialysis patients. 63 haemodialysis patients with 66 AV fistulas and AV grafts were treated by interventional stent-graft deployment from 2006 to 2012 at our hospital. Data of these patients were retrospectively analysed for location of deployed stent-grafts, occurrence and location of (re-)stenosis and (re-)thrombosis. Complex stenosis was the most frequent indication for stent-graft deployment (45.5%), followed by complications of angioplasty with vessel rupture or dissection (31.8%). A high rate of procedural success was achieved (98.5%). The most frequent location of the deployed stent-graft was the draining vein (66.7%). Stent-graft deployment was more frequent in AV grafts than in AV fistulas. Primary patency was 45.5% at 6 month, 31.3% at 12 month and 19.2% at 24 month. Primary patency was significantly better for AV fistulas than for AV grafts with deployed stent-grafts. Patency of the deployed stent-graft was much better than overall AV access primary patency with deployed stent-graft. Re-stenosis with thrombosis was the most frequent indication for re-intervention. Most frequent location of re-stenosis was the draining vein (37.1%), followed by stenosis at the AV access (29.5%) and the deployed stent-graft (23.5%). Re-stenosis and re-thrombosis remain frequent in AV fistulas and AV grafts in haemodialysis patients despite stent-graft deployment. Re-stenosis of the deployed stent-graft is, only in the minority of the cases, responsible for AV access dysfunction.

  15. Outcomes of AV Fistulas and AV Grafts after Interventional Stent-Graft Deployment in Haemodialysis Patients

    Energy Technology Data Exchange (ETDEWEB)

    Schmelter, Christopher, E-mail: christopher.schmelter@klinikum-ingolstadt.de; Raab, Udo, E-mail: udo.raab@klinikum-ingolstadt.de [Klinikum Ingolstadt, Department of Diagnostic and Interventional Radiology (Germany); Lazarus, Friedrich, E-mail: friedrich.lazarus@klinikum-ingolstadt.de [Klinikum Ingolstadt, Department of Nephrology (Germany); Ruppert, Volker, E-mail: volker.ruppert@klinikum-ingolstadt.de [Klinikum Ingolstadt, Department of Vascular Surgery (Germany); Vorwerk, Dierk, E-mail: dierk.vorwerk@klinikum-ingolstadt.de [Klinikum Ingolstadt, Department of Diagnostic and Interventional Radiology (Germany)

    2015-08-15

    PurposeThe study was designed to assess outcomes of arteriovenous (AV) accesses after interventional stent-graft deployment in haemodialysis patients.Materials and Methods63 haemodialysis patients with 66 AV fistulas and AV grafts were treated by interventional stent-graft deployment from 2006 to 2012 at our hospital. Data of these patients were retrospectively analysed for location of deployed stent-grafts, occurrence and location of (re-)stenosis and (re-)thrombosis. Complex stenosis was the most frequent indication for stent-graft deployment (45.5 %), followed by complications of angioplasty with vessel rupture or dissection (31.8 %).ResultsA high rate of procedural success was achieved (98.5 %). The most frequent location of the deployed stent-graft was the draining vein (66.7 %). Stent-graft deployment was more frequent in AV grafts than in AV fistulas. Primary patency was 45.5 % at 6 month, 31.3 % at 12 month and 19.2 % at 24 month. Primary patency was significantly better for AV fistulas than for AV grafts with deployed stent-grafts. Patency of the deployed stent-graft was much better than overall AV access primary patency with deployed stent-graft. Re-stenosis with thrombosis was the most frequent indication for re-intervention. Most frequent location of re-stenosis was the draining vein (37.1 %), followed by stenosis at the AV access (29.5 %) and the deployed stent-graft (23.5 %).ConclusionRe-stenosis and re-thrombosis remain frequent in AV fistulas and AV grafts in haemodialysis patients despite stent-graft deployment. Re-stenosis of the deployed stent-graft is, only in the minority of the cases, responsible for AV access dysfunction.

  16. Association of poly(4-hydroxystyrene)-block-poly(ethylene oxide) in aqueous solutions: block copolymer nanoparticles with intermixed blocks

    Czech Academy of Sciences Publication Activity Database

    Štěpánek, M.; Hajduová, J.; Procházka, K.; Šlouf, Miroslav; Nebesářová, Jana; Mountrichas, G.; Mantzaridis, Ch.; Pispas, S.

    2012-01-01

    Roč. 28, č. 1 (2012), s. 307-313 ISSN 0743-7463 R&D Projects: GA ČR GAP208/10/0353; GA ČR GCP205/11/J043; GA AV ČR KAN200520704 Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z60220518 Keywords : nanoparticles * poly(4-hydroxystyrene)-block-poly( ethylene oxide ) * PHOS-PEO Subject RIV: CD - Macromolecular Chemistry Impact factor: 4.187, year: 2012

  17. Strategiske beslutninger foran publikum : en spillteoretisk analyse av betingelser for utbrudd av borgerkrig

    OpenAIRE

    Meyer, Sunniva Frislid

    2006-01-01

    Borgerkrig modelleres i foreliggende litteratur enten som følge av privat informasjon om aktørenes forventede nytte av krig eller som følge av at myndighetene ikke troverdig kan forplikte seg til en fremforhandlet avtale. Eksisterende modeller overser i stor grad hvordan effekten av at myndighetene gir etter for en intern grupperings krav kan påvirke hvordan andre interne grupperinger forholder seg til myndighetene i fremtiden. Dersom myndighetene gir etter for en intern grupperings krav, kan...

  18. Praktisering av krav til rettvisende oversikt i årsberetning : en analyse av regnskapspraksis i fiskeindustrien

    OpenAIRE

    Vajenina, Larissa

    2012-01-01

    Dette er en studie av årsberetning, og videre praktisering av rettvisende oversikt i årsberetning. Studiens problemstilling: ”Hvordan blir kravene om rettvisende oversikt i årsberetning praktisert i utvalgte selskaper i Norge?” I denne studien ser jeg på praksis av rettvisende oversikt i årsberetning. Lovkravet til rettvisende oversikt i årsberetning fremgår av rskl.§ 3-3a, 2.-4.ledd. Innhold i rettvisende oversikt er grundig beskrevet under punkt 2.5 i NRS 16 Årsberetning. Reg...

  19. Block copolymer structures in nano-pores

    Science.gov (United States)

    Pinna, Marco; Guo, Xiaohu; Zvelindovsky, Andrei

    2010-03-01

    We present results of coarse-grained computer modelling of block copolymer systems in cylindrical and spherical nanopores on Cell Dynamics Simulation. We study both cylindrical and spherical pores and systematically investigate structures formed by lamellar, cylinders and spherical block copolymer systems for various pore radii and affinity of block copolymer blocks to the pore walls. The obtained structures include: standing lamellae and cylinders, ``onions,'' cylinder ``knitting balls,'' ``golf-ball,'' layered spherical, ``virus''-like and mixed morphologies with T-junctions and U-type defects [1]. Kinetics of the structure formation and the differences with planar films are discussed. Our simulations suggest that novel porous nano-containers can be formed by confining block copolymers in pores of different geometries [1,2]. [4pt] [1] M. Pinna, X. Guo, A.V. Zvelindovsky, Polymer 49, 2797 (2008).[0pt] [2] M. Pinna, X. Guo, A.V. Zvelindovsky, J. Chem. Phys. 131, 214902 (2009).

  20. Veileder for kravspesifikasjon for leie av kontorarealer

    DEFF Research Database (Denmark)

    Førland-Larsen, Arne

    Investorer og leietakere blir stadig mer interessert i helse- og miljøkvaliteter. Men kunnskapen er lav hos de fleste om hva de skal etterspørre og hvordan slike kvaliteter kan dokumenteres. Meglere har en viktig rolle som formidler av kvaliteter. Grønn Byggallianse har i samarbeid med blant annet...... Norsk Eiendom, Enova og NGBC utarbeidet en mal for standard kravspesifikasjon for leie av kontorlokaler. Målet med malen er å bidra til at leietager får det produktet han trenger til riktig pris og at man unngår unødig miljøbelastning. Målet er videre at å bidra og stimulere til, at innleie....../utleie prosesser startes med en dialogbasert prosess. Standarden er tenkt som et hjelpemiddel til en systematisk gjennomgang av, og diskusjon av hvilke kvaliteter som har prioritet, høy, middel eller lav prioritet for leietaker. Resultatet av dialog og diskusjon fastlegger endelige krav til kvalitet og...

  1. Solar modulation of Northern Hemisphere winter blocking

    Czech Academy of Sciences Publication Activity Database

    Barriopedro, D.; García-Herrera, R.; Huth, Radan

    2008-01-01

    Roč. 113, D14 (2008), D14118/1-D14118/11 ISSN 0148-0227 R&D Projects: GA AV ČR IAA3042401; GA AV ČR IAA300420805 Grant - others:VALIMOD(ES) REN2002-04558-C04-01 Institutional research plan: CEZ:AV0Z30420517 Keywords : solar activity cycle * atmospheric blocking * climate variability * atmospheric circulation * solar-terrestrial relationships Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 3.147, year: 2008

  2. Non-physiological increase of AV conduction time in sinus disease patients programmed in AAIR-based pacing mode.

    Science.gov (United States)

    Mabo, Philippe; Cebron, Jean-Pierre; Solnon, Aude; Tassin, Aude; Graindorge, Laurence; Gras, Daniel

    2012-11-01

    The EVOCAV(DS) trial aimed to quantify the paradoxal atrioventricular (AV) conduction time lengthening in sinus node (SD) patients (pts) paced in AAIR-based pacing mode. SD pts, implanted with dual-chamber pacemaker programmed in AAIR-based pacing mode, were randomized in two arms for a 1-month period: the low atrial pacing (LAP; basic rate at 60 bpm, dual sensor with minimal slope) and the high atrial pacing (HAP; basic rate at 70 bpm, dual sensor with optimized slope, overdrive pacing) arm. At 1 month, crossover was performed for an additional 1-month period. AV conduction time, AV block occurrence and AV conduction time adaptation during exercise were ascertained from device memories at each follow-up. Seventy-nine pts participated to the analysis (75 ± 8 years; 32 male; PR = 184 ± 38 ms; bundle branch block n = 12; AF history n = 36; antiarrhythmic treatment n = 53; beta-blockers n = 27; class III/Ic n = 18; both n = 8). The mean AV conduction time was significantly greater during the HAP (275 ± 51 ms) vs. LAP (263 ± 49 ms) period (p AV blocks occurred in 49 % of pts in the HAP vs. 19 % in the LAP period (p AV conduction time during exercise. AAIR-based pacing in SD pts may induce a significant lengthening of pts' AV conduction time, including frequent abnormal adaptation of AV conduction time during exercise.

  3. Dynamics of AV coupling during human atrial fibrillation: role of atrial rate.

    Science.gov (United States)

    Masè, M; Marini, M; Disertori, M; Ravelli, F

    2015-07-01

    The causal relationship between atrial and ventricular activities during human atrial fibrillation (AF) is poorly understood. This study analyzed the effects of an increase in atrial rate on the link between atrial and ventricular activities during AF. Atrial and ventricular time series were determined in 14 patients during the spontaneous acceleration of the atrial rhythm at AF onset. The dynamic relationship between atrial and ventricular activities was quantified in terms of atrioventricular (AV) coupling by AV synchrogram analysis. The technique identified n:m coupling patterns (n atrial beats in m ventricular cycles), quantifying their percentage, maximal length, and conduction ratio (= m/n). Simulations with a difference-equation AV model were performed to correlate the observed dynamics to specific atrial/nodal properties. The atrial rate increase significantly affected AV coupling and ventricular response during AF. The shortening of atrial intervals from 185 ± 32 to 165 ± 24 ms (P AV patterns with progressively decreasing m/n ratios (from conduction ratio = 0.34 ± 0.09 to 0.29 ± 0.08, P AV block and coupling instability at higher atrial rates were associated with increased ventricular interval variability (from 123 ± 52 to 133 ± 55 ms, P AV pattern transitions and coupling instability in patients were predicted, assuming the filtering of high-rate irregular atrial beats by the slow recovery of nodal excitability. These results support the role of atrial rate in determining AV coupling and ventricular response and may have implications for rate control in AF. Copyright © 2015 the American Physiological Society.

  4. Vinkelegenskapsklassificering av svetsglas : Angående utvecklingen av en conometerbaserad klassifikationsutrustning.

    OpenAIRE

    Sundell, Erik

    2016-01-01

    Denna rapport är skriven för optikgruppen på 3M Svenska ABs forsknings- och utvecklingsavdelning i Gagnef. Rapporten beskriver den driftsatta tekniken för vinkelegenskapsklassificeringar av ADFer samt den berörda fysiken. Rapporten avser att underlätta det ofullständiga arbetet av att ackreditera optikgruppens förmåga att genomföra dessa klassifikationer. Rapporten inleds med att beskriva fysiken relaterad till mätning av mänsklig ljusupplevelse. Därefter presenteras bland annat tekniken krin...

  5. Vurdering av strømforhold og partikkelspredning ved etablering av ny dypvannskai ved Rana Industriterminal

    OpenAIRE

    Staalstrøm, Andre; Kempa, Magdalena

    2015-01-01

    Det skal etableres en ny dypvannskai ved Rana Industriterminal, og i den forbindelse har NIVA gjort vurderinger av strømforhold i området og partikkelspredning i anleggsperioden. I denne rapporten er det tatt utgangspunkt i at 135 000 m³ med masse skal mudres opp. Det er videre antatt at 2 % av denne massen spres i Ranfjorden, og dette utgjør 1620 tonn tørr masse. Denne mengden tilsvarer den samme mengden partikler som kan tilføres fjorden fra Ranelva i løpet av en ukes tid, og anses ikke som...

  6. 125l-Labeled PEO/PLA block copolymer: biodistribution studies in rats

    Czech Academy of Sciences Publication Activity Database

    Nováková, K.; Lázníček, M.; Rypáček, František; Machová, Luďka

    2002-01-01

    Roč. 17, č. 4 (2002), s. 285-296 ISSN 0883-9115 R&D Projects: GA AV ČR KSK4055109 Institutional research plan: CEZ:AV0Z4050913 Keywords : block copolymer micelles * poly(D,L-lactide-block-ethylene oxide) * biodistribution Subject RIV: CC - Organic Chemistry Impact factor: 0.525, year: 2002

  7. Artificial vision support system (AVS(2)) for improved prosthetic vision.

    Science.gov (United States)

    Fink, Wolfgang; Tarbell, Mark A

    2014-11-01

    State-of-the-art and upcoming camera-driven, implanted artificial vision systems provide only tens to hundreds of electrodes, affording only limited visual perception for blind subjects. Therefore, real time image processing is crucial to enhance and optimize this limited perception. Since tens or hundreds of pixels/electrodes allow only for a very crude approximation of the typically megapixel optical resolution of the external camera image feed, the preservation and enhancement of contrast differences and transitions, such as edges, are especially important compared to picture details such as object texture. An Artificial Vision Support System (AVS(2)) is devised that displays the captured video stream in a pixelation conforming to the dimension of the epi-retinal implant electrode array. AVS(2), using efficient image processing modules, modifies the captured video stream in real time, enhancing 'present but hidden' objects to overcome inadequacies or extremes in the camera imagery. As a result, visual prosthesis carriers may now be able to discern such objects in their 'field-of-view', thus enabling mobility in environments that would otherwise be too hazardous to navigate. The image processing modules can be engaged repeatedly in a user-defined order, which is a unique capability. AVS(2) is directly applicable to any artificial vision system that is based on an imaging modality (video, infrared, sound, ultrasound, microwave, radar, etc.) as the first step in the stimulation/processing cascade, such as: retinal implants (i.e. epi-retinal, sub-retinal, suprachoroidal), optic nerve implants, cortical implants, electric tongue stimulators, or tactile stimulators.

  8. Att arbeta tillsammans - utvärdering av nytt kursupplägg av examensarbeten

    Directory of Open Access Journals (Sweden)

    Sofia Thorsson

    2015-06-01

    Full Text Available Grupphandledning av examensarbete inom geografi, med fokus på naturgeografi, vid Göteborgs Universitet infördes 2012 som ett komplement till den individuella handledningen i syfte att öka genomströmningen av studenter samt kvaliteten på arbetena. I denna artikel presenteras och utvärderas det aktuella kursupplägget. Såväl genomströmningen som kvaliteten (bearbetning och tolkning av materialet, teorianknytning, disposition och språk ökade efter införandet av grupphandledning, vilket i linje med tidigare studier visar att grupphandledning är ett bra komplement till den traditionella individuella handledningen.

  9. Digitala backspeglar - Fysisk-ergonomiska konsekvenser av arrangemang av digitala backspeglar i en lastbilshytt

    OpenAIRE

    LUNDIN, ARVID; ZAIMOVIC, NEDIM

    2016-01-01

    Backspeglar på dagens lastbilar bidrar till fordonets bränsleförbrukning på grund av det luftmotstånd som de orsakar. Detta bidrag kan minskas om de fysiska speglarna ersätts av digitala motsvarigheter, i form av kameror monterade på lastbilens utsida och bildskärmar placerade inuti lastbilshytten. Ett sådant ingrepp medför en rad möjligheter för förbättring av inte bara fordonets verkningsgrad utan även förarmiljön. Med digitala backspeglar så skulle det vara möjligt att visa stödjande grafi...

  10. Idiopathic Paroxysmal Atrio-Ventricular Block. What is The Mechanism?

    Science.gov (United States)

    Guerrero-Márquez, Francisco J; Arana-Rueda, Eduardo; Pedrote, Alonso

    2016-01-01

    Idiopathic paroxysmal atrioventricular (AV) block poses a true diagnostic challenge. What is clear about this entity is the confusion about its definition and consequently about its etiology. According to certain sources, the diagnosis of this block requires the lack of a structural cardiac pathology that justifies the observed manifestations and an absence of electrocardiographic disorders prior to an episode. The clinical presentation of idiopathic paroxysmal AV block does not differ from that of another cardiogenic syncope or of a vasovagal syncope with a significant cardioinhibitory component. With respect to the mechanism that explains this block, it has been postulated that patients with low basal adenosine levels exhibit hyperaffinity of the A2 receptors of the AV node. Variations in plasma adenosine levels may favor episodes of paroxysmal AV block. The diagnosis of this block is complex and can require years to determine. Routine electrophysiological examination of these patients is not cost effective due to the low sensitivity and specificity of this approach. Numerous groups have supported the use of an implantable loop recorder to substantiate AV block paroxysms and assess their clinical correlations. Permanent stimulation devices are utilized to reduce syncopal recurrence.

  11. Konsum av risiko-matvarer - Beskrivelse av en undersøkelse som skal kartlegge konsum av matvarer med betydning for inntaket av miljøgifter

    Directory of Open Access Journals (Sweden)

    Helle Margrete Meltzer

    2009-11-01

    Full Text Available  SAMMENDRAGI perioden 1999-2001 vil det bli gjennomført tre kostholdsundersøkelser som til sammen skal kartlegge konsum avmatvarer med betydning for inntaket av miljøgifter i Norge, fortrinnsvis kadmium, kvikksølv, PCB og dioksiner.Disse giftene finnes hovedsakelig i krabbe, flatfisk, skjell, gjedde og abbor, lever eller nyre fra vilt og viltvoksendesopp. Fordi gjennomsnittskonsumet er lavt, spørres det ikke spesifikt om disse matvarene i landsdekkende kostholdsundersøkelsersom 'Norkost'. Hensikten med studien er å kunne gi en bedre beskrivelse av eksponeringsfordelingeni befolkningen med tanke på miljøgifter. Fordelingen er antakelig skjev, dvs. et stort antall personerventes å ha et lavt inntak og noen få personer ventes å ha et relativt høyt inntak av de undersøkte stoffene. Eventuelleukjente risikogrupper vil kunne avdekkes, og det er av stor interesse å undersøke hvor stor eksponeringen i deutsatte gruppene er.Del A av undersøkelsen er landsdekkende og omfatter en postal frekvensundersøkelse til 10 000 tilfeldig valgtepersoner mellom 18 og 79 år. Del B omfatter en postal frekvensundersøkelse til 6000 tilfeldig valgte personer i sekskommuner, der tre er kystkommuner og tre er innlandskommuner. Kommunene blir valgt ut fra kjennskap til godtilgang på de aktuelle matvarene. Vi antar at der tilgangen på matvarene er god, er konsumet høyere. Del C avundersøkelsen vil omfatte høykonsumenter av aktuelle matvarer, valgt fra del B av undersøkelsen. Dette vil være endybdestudie der analyser av miljøgifter i blod, hår og urin også skal inngå.Undersøkelsen er den første i sitt slag her til lands og vi kjenner ikke til at tilsvarende studier er gjort i andreland. Hensikten med artikkelen er å gi en beskrivelse av undersøkelsen i en tidlig fase av gjennomføringen.Meltzer HM, Bergsten C, Stene LC, Stigum H, Wiborg ML, Lund-Larsen K, Alexander J. Consumption ofcontaminated foods – Description of a dietary survey

  12. Whether noninvasive optimization of AV and VV delays improves the response to cardiac resynchronization therapy.

    Science.gov (United States)

    Urbanek, Bożena; Chudzik, Michał; Klimczak, Artur; Rosiak, Marcin; Lewek, Joanna; Wranicz, Jerzy Krzysztof

    2013-01-01

    Device optimization is not routinely performed in patients who underwent cardiac resynchronization therapy (CRT) device implantation. Noninvasive optimization of CRT devices by measurement of cardiac output (CO) can be used as a simple method to assess ventricular systolic performance. The aim of this study was to assess whether optimization of atrioventricular (AV) and interventricular (VV) delay can improve hemodynamic response to CRT and whether this optimization should be performed for each patient individually. Twenty patients with advanced heart failure New York Heart Association (NYHA) class III/IV, left ventricular ejection fraction ≤ 35% and left bundle branch block (QRS ≥ 120 ms) in sinus rhythm were evaluated from 24 h to 48 h after implantation of a CRT device by means of impedance cardiography (ICG). CO was first measured at each patient's intrinsic rhythm. Patients then underwent adjustments of AV and VV delay from 80 ms to 140 ms and from -60 ms to +60 ms, respectively in 20 ms increment steps and CO at each setting was measured by ICG. Both AV and VV delays were programmed according to the greatest improvement in CO compared to intrinsic rhythm. There was a statistically signifi cant increase in CO measured at the intrinsic rhythm compared to different AV delay by mean of 21% (3.8 ± 1.0 vs. 4.6 ± 0.1 L/min, p AV/VV delays with left ventricle-preexcitation or simultaneous biventricular pacing caused additional increased CO from intrinsic rhythm by mean of 32.6% (3.8 ± 1.0 vs. 5.04 ± ± 1.0 L/min, p AV/VV setting delays also resulted in improved hemodynamic responses compared to VV factory setting delay. Both AV and VV delay optimization should be performed in clinical practice. Optimal AV delay improved outcome. However, combination of optimized AV/VV delays provided the best hemodynamic response. Optimized AV/VV delays with left ventricle-preexcitation or simultaneous biventricular pacing increased hemodynamic output compared to intrinsic

  13. En analyse knyttet til bruk av cookies.

    OpenAIRE

    Hørthe, Stine

    2012-01-01

    Cookies er små informasjonskapsler som Internettaktører legger igjen på en slutt-brukers datamaskin ved surfing på nettsider. Bruken av cookies på nettsider har fåttøkt oppmerksomhet de siste årene. I tillegg til å muliggjøre flere nyttige funksjonerfor en tjenestetilbyder, som for eksempel brukerrettet reklame og informasjonsinn-henting, har det den siste tiden blitt rettet en del kritiske spørsmål rundt bruken avcookies samt spørsmål knyttet til personvern og juridiske aspekt. Denne oppgave...

  14. Instrumentering av Bergsøysundbrua og Gjemnesundbrua

    OpenAIRE

    Dahlen, Adrian; Lystad, Tor Martin

    2013-01-01

    Gjemnessundbrua og Bergsøysundbrua på Europavei E39 i Møre og Romsdal, skal instrumenteres for identifikasjon av strukturelle og dynamiske egenskaper. Denne rapporten omhandler dokumentasjon og beskrivelse av det utførte arbeidet ved monteringen av måleutstyret. Det er også gjort analyser av de ulike konstruksjonsdelene akselerometersensorer og anemometre er montert på. Til slutt er de initielle responssignalene fra systemet behandlet, der egenfrekvenser og dempningsegenskaper til bruene blir...

  15. Betydelsen av taktil massage i omvårdnaden av dementa patienter- En systematisk litteraturstudie

    OpenAIRE

    Wetterström, Marina; Swan, Emelie

    2008-01-01

    Syftet med denna systematiska litteraturstudie var att se vilka effekter taktil massage ger hos personer med demens. Sökning av artiklar har gjorts på databaserna CINAHL, ELIN@Dalarna och PubMed där sökorden dementia, massage, nursing, older people, Therapeutic touch och touch användes i olika kombinationer. Litteraturstudien består av kvantitativa och kvalitativa artiklar. Artiklarna skulle vara vetenskapliga och inte publicerade före 1995, de skulle även svara på syfte och frågeställning. F...

  16. Upplevelser av "Employer Branding" : En kvalitativ fallstudie av anställda hos BA

    OpenAIRE

    Hermansson, Otto; Elisabeth, Mackenhauer

    2016-01-01

    Syftet med denna studie var att undersöka hur medarbetarna på BA (fiktivt namn) upplever organisationens interna Employer Branding-arbete samt att belysa de aspekter som eventuellt skiljer strategi mot upplevelse. Det gjordes ett målinriktat urval av organisation medan valet av deltagare var ett slumpmässigt urval vilket resulterade i åtta respondenter (n= 8). Studien var en kvalitativ fallstudie med ett psykologiskt angreppssätt och innehöll en ostrukturerad intervju som tillsammans m...

  17. Implementeringsforskning: vitenskap for forbedring av praksis

    Directory of Open Access Journals (Sweden)

    Signe Flottorp

    2013-11-01

    Full Text Available Medisinsk forskning har ført til store framskritt de siste tiårene. Det er investert mye mer ressurser på basalforskning og klinisk forskning enn på å utvikle og evaluere metoder for å sikre at pasientene får nytte av forskningen. Formålet med implementeringsforskning er å redusere gapet mellom forskning og praksis, ved å utvikle og evaluere tiltak som kan sikre at behandlingen som pasientene mottar er kunnskapsbasert, at den er omsorgsfull og av god kvalitet.I denne artikkelen gjør vi rede for hva implementering og implementeringsforskning er. Vi belyser historikken til denne unge vitenskapen, og illustrerer mangfoldet i de faglige tilnærmingene og begrepene som brukes om det å få forskning brukt i praksis. Det finnes en rekke teorier om endring av atferd, både på individnivå og på organisatorisk nivå. Teoriene er imidlertid i liten grad testet empirisk, særlig når det gjelder å endre atferd i helsetjenesten.Systematiske oversikter over metodisk gode studier er den beste kilden til informasjon om effekt av implementeringstiltak. The Cochrane Effective Practice and Organisation of Care Group (EPOC er en viktig kilde for slike oversikter. De systematiske oversiktene som er utarbeidet på dette feltet viser at passive dissemineringstiltak har begrenset effekt, mens mer aktive tiltak kan ha liten til moderat effekt. Det er ofte betydelig variasjon i effekt på tvers av studiene. Det er derfor viktig å få bedre kunnskap om hvilke faktorer som kan forklare slike forskjeller i effekt.Vi gir eksempler på norske implementeringsstudier, og refererer bidrag fra forskere ved Kunnskapssenteret. Implementeringsforskningen kan, hvis den lykkes, sikre pasientene bedre behandling.Flottorp S, Aakhus E. Implementation research: science for improving practice. Nor J Epidemiol 201 3; 23 (2: 187-196.ENGLISH SUMMARY Medical research has led to major advances in recent decades. More resources have been invested in basic and clinical research

  18. AV3V lesions attenuate the cardiovascular responses produced by blood-borne excitatory amino acid analogs

    Science.gov (United States)

    Whalen, E. J.; Beltz, T. G.; Lewis, S. J.; Johnson, A. K.

    1999-01-01

    Systemic injections of the excitatory amino acid (EAA) analogs, kainic acid (KA) and N-methyl-D-aspartate (NMDA), produce a pressor response in conscious rats that is caused by a centrally mediated activation of sympathetic drive and the release of arginine vasopressin (AVP). This study tested the hypothesis that the tissue surrounding the anteroventral part of the third ventricle (AV3V) plays a role in the expression of the pressor responses produced by systemically injected EAA analogs. Specifically, we examined whether prior electrolytic ablation of the AV3V region would affect the pressor responses to KA and NMDA (1 mg/kg iv) in conscious rats. The KA-induced pressor response was smaller in AV3V-lesioned than in sham-lesioned rats (11 +/- 2 vs. 29 +/- 2 mmHg; P response in sham-lesioned but not AV3V-lesioned rats (+27 +/- 3 vs. +1 +/- 2 mmHg; P response in ganglion-blocked sham-lesioned rats was abolished by a vasopressin V1-receptor antagonist. Similar results were obtained with NMDA. The pressor response to AVP (10 ng/kg iv) was slightly smaller in AV3V-lesioned than in sham-lesioned ganglion-blocked rats (45 +/- 3 vs. 57 +/- 4 mmHg; P responses to systemically injected EAA analogs are smaller in AV3V-lesioned rats. The EAA analogs may produce pressor responses by stimulation of EAA receptors in the AV3V region, or the AV3V region may play an important role in the expression of these responses.

  19. Design av arkitektur for evolusjonær maskinvare basert på intern rekonfigurering av FPGA

    OpenAIRE

    Senland, Geir Aarstad

    2008-01-01

    Det ble i denne oppgaven designet en arkitektur for evolusjonær maskinvare basert på intern rekonfigurering av FPGA. Til å utføre intern rekonfigurasjonen av FPGA-en ble internal configuration access port (ICAP) brukt. Programmet PlanAhead fra Xilinx ble brukt til å designe den interne rekonfigurasjonsdelen av arkitekturen. Motivasjonen for oppgaven var å introdusere fleksibilitet til et signal- og klassifikasjonssystem, ved å bruke intern rekonfigurasjon av FPGA. Klassifikasjonssystemet ...

  20. AVS user's guide on the basis of practice

    International Nuclear Information System (INIS)

    Masuko, Kenji; Kato, Katsumi; Kume, Etsuo; Fujii, Minoru.

    1997-07-01

    The special guides for the use of visualization software AVS have been developed at Japan Atomic Energy Research Institute (JAERI). The purpose of these guides is to help the AVS users understand easily the use of the one, due to the fact that it is so difficult for beginners to understand the original manuals. In this report, 'Transportation Evacuation Simulation' is taken up as an object of visualization, and the procedure of visualization and images recording by using the AVS are described. By using the AVS according to this report, a series of the procedure which are necessary for use of the AVS can be acquired. (author)

  1. Analys av nickel med ICP-MS

    OpenAIRE

    Wallman, Karin; Löfgren, Stefan; Sonesten, Lars; Demandt, Christian

    2009-01-01

    Vid en granskning av nickelhalter för perioden 1985-2007 upptäcktes ett nivåskifte i tidsserierna på flera stationer mellan 2001 och 2002. Skiftet visade sig bero på att prover innan 2002 inte korrigerades för kalciuminterferens, medan prover under åren 2002-2007 korrigerades. Syftet med denna rapport är att utreda om resultaten före 2002 i efterhand kan korrigeras för kalciuminterferensen. Från 2002 finns ett antal prover (N=347) med resultat som både är kalciumkorrigerade och som inte är de...

  2. Compatibilization efficiency of styrene-butadiene block copolymers as a function of their block number

    Czech Academy of Sciences Publication Activity Database

    Vranješ, N.; Lednický, František; Kotek, Jiří; Baldrian, Josef; Rek, V.; Fortelný, Ivan; Horák, Zdeněk

    2008-01-01

    Roč. 108, č. 1 (2008), s. 466-472 ISSN 0021-8995 R&D Projects: GA ČR GA106/06/0729 Institutional research plan: CEZ:AV0Z40500505 Keywords : blends * block copolymer * compatibility Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.187, year: 2008

  3. Cardiac resynchronization therapy and AV optimization increase myocardial oxygen consumption, but increase cardiac function more than proportionally.

    Science.gov (United States)

    Kyriacou, Andreas; Pabari, Punam A; Mayet, Jamil; Peters, Nicholas S; Davies, D Wyn; Lim, P Boon; Lefroy, David; Hughes, Alun D; Kanagaratnam, Prapa; Francis, Darrel P; Whinnett, Zachary I

    2014-02-01

    The mechanoenergetic effects of atrioventricular delay optimization during biventricular pacing ("cardiac resynchronization therapy", CRT) are unknown. Eleven patients with heart failure and left bundle branch block (LBBB) underwent invasive measurements of left ventricular (LV) developed pressure, aortic flow velocity-time-integral (VTI) and myocardial oxygen consumption (MVO2) at 4 pacing states: biventricular pacing (with VV 0 ms) at AVD 40 ms (AV-40), AVD 120 ms (AV-120, a common nominal AV delay), at their pre-identified individualised haemodynamic optimum (AV-Opt); and intrinsic conduction (LBBB). AV-120, relative to LBBB, increased LV developed pressure by a mean of 11(SEM 2)%, p=0.001, and aortic VTI by 11(SEM 3)%, p=0.002, but also increased MVO2 by 11(SEM 5)%, p=0.04. AV-Opt further increased LV developed pressure by a mean of 2(SEM 1)%, p=0.035 and aortic VTI by 4(SEM 1)%, p=0.017. MVO2 trended further up by 7(SEM 5)%, p=0.22. Mechanoenergetics at AV-40 were no different from LBBB. The 4 states lay on a straight line for Δexternal work (ΔLV developed pressure × Δaortic VTI) against ΔMVO2, with slope 1.80, significantly >1 (p=0.02). Biventricular pacing and atrioventricular delay optimization increased external cardiac work done but also myocardial oxygen consumption. Nevertheless, the increase in cardiac work was ~80% greater than the increase in oxygen consumption, signifying an improvement in cardiac mechanoenergetics. Finally, the incremental effect of optimization on external work was approximately one-third beyond that of nominal AV pacing, along the same favourable efficiency trajectory, suggesting that AV delay dominates the biventricular pacing effect - which may therefore not be mainly "resynchronization". © 2013. Published by Elsevier Ireland Ltd. All rights reserved.

  4. Når kontakter betyr alt : En studie av bruken av nettverksmediet LinkedIn

    OpenAIRE

    Blaalid, Maren Hyvang

    2012-01-01

    LinkedIn er et av de mest populære sosiale mediene i Norge og tiltrekker seg stadig flere medlemmer. I denne masteroppgaven studerer jeg bruken av LinkedIn for å undersøke hva som er det særegne ved dette nettverksmediet. Jeg har utført en spørreundersøkelse blant 280 brukere for å få innsikt i hvem de er, hvorfor de bruker LinkedIn og hvordan de gjør det. Funnene fra analysen viser at brukerne kjennetegnes ved at de er selvstendige og formålsrasjonelle, som bruker LinkedIn strategisk for å n...

  5. Characterization of nanoparticles based on block copolymer micelles

    Czech Academy of Sciences Publication Activity Database

    Pleštil, Josef; Pospíšil, Herman; Kříž, Jaroslav; Kadlec, Petr; Tuzar, Zdeněk; Cubitt, R.

    2001-01-01

    Roč. 17, č. 21 (2001), s. 6699-6704 ISSN 0743-7463 R&D Projects: GA AV ČR KSK4050111; GA ČR GA203/00/1317; GA ČR GA203/01/0536 Institutional research plan: CEZ:AV0Z4050913 Keywords : block copolymer micelles * nanoparticles * small - angle neutron scattering Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.963, year: 2001

  6. 18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy.

    Science.gov (United States)

    Passamonti, Luca; Vázquez Rodríguez, Patricia; Hong, Young T; Allinson, Kieren S J; Williamson, David; Borchert, Robin J; Sami, Saber; Cope, Thomas E; Bevan-Jones, W Richard; Jones, P Simon; Arnold, Robert; Surendranathan, Ajenthan; Mak, Elijah; Su, Li; Fryer, Tim D; Aigbirhio, Franklin I; O'Brien, John T; Rowe, James B

    2017-03-01

    The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these tauopathies and clinical trials of disease-modifying therapies. New radioligands for positron emission tomography have generated considerable interest, and controversy, in their potential as tau biomarkers. We assessed the radiotracer 18F-AV-1451 with positron emission tomography imaging to compare the distribution and intensity of tau pathology in 15 patients with Alzheimer's pathology (including amyloid-positive mild cognitive impairment), 19 patients with progressive supranuclear palsy, and 13 age- and sex-matched controls. Regional analysis of variance and a support vector machine were used to compare and discriminate the clinical groups, respectively. We also examined the 18F-AV-1451 autoradiographic binding in post-mortem tissue from patients with Alzheimer's disease, progressive supranuclear palsy, and a control case to assess the 18F-AV-1451 binding specificity to Alzheimer's and non-Alzheimer's tau pathology. There was increased 18F-AV-1451 binding in multiple regions in living patients with Alzheimer's disease and progressive supranuclear palsy relative to controls [main effect of group, F(2,41) = 17.5, P AV-1451 binding was significantly increased in patients with Alzheimer's disease, relative to patients with progressive supranuclear palsy and with control subjects, in the hippocampus and in occipital, parietal, temporal, and frontal cortices (t's > 2.2, P's AV-1451 binding was elevated in the midbrain (t = 2.1, P AV-1451 uptake in the putamen, pallidum, thalamus, midbrain, and in the dentate nucleus of the cerebellum (t's > 2.7, P's AV-1451 strongly bound to Alzheimer-related tau pathology, but less specifically in progressive supranuclear palsy. 18F-AV-1451 binding to the basal ganglia was strong in all groups in vivo. Postmortem histochemical staining showed absence of

  7. Functional mathematical model of dual pathway AV nodal conduction.

    Science.gov (United States)

    Climent, A M; Guillem, M S; Zhang, Y; Millet, J; Mazgalev, T N

    2011-04-01

    Dual atrioventricular (AV) nodal pathway physiology is described as two different wave fronts that propagate from the atria to the His bundle: one with a longer effective refractory period [fast pathway (FP)] and a second with a shorter effective refractory period [slow pathway (SP)]. By using His electrogram alternance, we have developed a mathematical model of AV conduction that incorporates dual AV nodal pathway physiology. Experiments were performed on five rabbit atrial-AV nodal preparations to develop and test the presented model. His electrogram alternances from the inferior margin of the His bundle were used to identify fast and slow wave front propagations. The ability to predict AV conduction time and the interaction between FP and SP wave fronts have been analyzed during regular and irregular atrial rhythms (e.g., atrial fibrillation). In addition, the role of dual AV nodal pathway wave fronts in the generation of Wenckebach periodicities has been illustrated. Finally, AV node ablative modifications have been evaluated. The model accurately reproduced interactions between FP and SP during regular and irregular atrial pacing protocols. In all experiments, specificity and sensitivity higher than 85% were obtained in the prediction of the pathway responsible for conduction. It has been shown that, during atrial fibrillation, the SP ablation significantly increased the mean HH interval (204 ± 39 vs. 274 ± 50 ms, P AV node mechanisms and should be considered as a step forward in the studies of AV nodal conduction.

  8. Pollen transmission of asparagus virus 2 (AV-2) may facilitate mixed infection by two AV-2 isolates in asparagus plants.

    Science.gov (United States)

    Kawamura, Ryusuke; Shimura, Hanako; Mochizuki, Tomofumi; Ohki, Satoshi T; Masuta, Chikara

    2014-09-01

    Asparagus virus 2 (AV-2) is a member of the genus Ilarvirus and thought to induce the asparagus decline syndrome. AV-2 is known to be transmitted by seed, and the possibility of pollen transmission was proposed 25 years ago but not verified. In AV-2 sequence analyses, we have unexpectedly found mixed infection by two distinct AV-2 isolates in two asparagus plants. Because mixed infections by two related viruses are normally prevented by cross protection, we suspected that pollen transmission of AV-2 is involved in mixed infection. Immunohistochemical analyses and in situ hybridization using AV-2-infected tobacco plants revealed that AV-2 was localized in the meristem and associated with pollen grains. To experimentally produce a mixed infection via pollen transmission, two Nicotiana benthamiana plants that were infected with each of two AV-2 isolates were crossed. Derived cleaved-amplified polymorphic sequence analysis identified each AV-2 isolate in the progeny seedlings, suggesting that pollen transmission could indeed result in a mixed infection, at least in N. benthamiana.

  9. Effekt av melkesyrebakteriers metabolisme på utviklingen av Escherichia coli O157:H7 i melk

    OpenAIRE

    Westblad, Anne Margrethe

    2010-01-01

    Dagens regelverk sier at all melk som omsettes skal være varmebehandlet, men åpner samtidig for salg av melkeprodukter basert på upasteurisert melk, forutsatt overholdelse av visse krav. Dermed kan småskalavirksomheter framstille melkeprodukter av upasteurisert melk hvis de skulle ønske det. Et slikt ønske er ofte begrunnet i tradisjoner og praktiske forhold. I tillegg er det flere som påstår at råmelk er sunnere enn pasteurisert melk og at råmelkas mikroflora hemmer vekst av uønskede bakteri...

  10. Farmakologisk behandling av antisosiale lidelser : en litteraturstudie av evidensgrunnlaget for famakologisk behandling av psykopati og assosierte antisosiale personlighetstrekk og atferdsmønster

    OpenAIRE

    Romberg, Sara Montes

    2016-01-01

    Bakgrunn: Psykoterapeutiske og atferdsbaserte intervensjoner har vist seg å ha liten effekt ved antisosiale lidelser. Individer med antisosiale lidelser anses derfor som en relativt behandlingsresistent pasientgruppe, hvilket tyder på et behov for utvikling av alternative behandlingstilnærminger. Med bakgrunn i dette søker følgende studie å utforske evidensgrunnlaget for farmakologiske behandling av antisosiale lidelser og trekk. Metode: Litteratursøk i databasene BIBSYS, ProQuest, Web of ...

  11. Modification of polylactide surfaces with lactide-ethylene oxide functional block copolymers: Accessibility of functional groups

    Czech Academy of Sciences Publication Activity Database

    Třesohlavá, Eliška; Popelka, Štěpán; Machová, Luďka; Rypáček, František

    2010-01-01

    Roč. 11, č. 1 (2010), s. 68-75 ISSN 1525-7797 R&D Projects: GA AV ČR 1QS500110564 Institutional research plan: CEZ:AV0Z40500505 Keywords : polylactide * poly(lactide)-block-poly( ethylene oxide ) * biomimetic Subject RIV: CD - Macromolecular Chemistry Impact factor: 5.327, year: 2010

  12. Dynamics of chain exchange between self-assembled diblock copolymer micelles of poly(ethylene oxide)-block-polylactide studied by direct nonradiative excitation energy transfer

    Czech Academy of Sciences Publication Activity Database

    Popelka, Štěpán; Machová, Luďka; Rypáček, František; Špírková, Milena; Štěpánek, M.; Matějíček, P.; Procházka, K.

    2005-01-01

    Roč. 70, č. 11 (2005), s. 1811-1828 ISSN 0010-0765 R&D Projects: GA AV ČR IAA4050202; GA AV ČR IAA400500505 Institutional research plan: CEZ:AV0Z40500505 Keywords : block copolymers * self-assembly * micelles Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.949, year: 2005

  13. Fiskeoppdrett og verdsettelse : en analyse av resultatjustering og modeller for identifikasjon av slik aktivitet

    OpenAIRE

    Aaker, Harald

    2005-01-01

    Regnskapsinformasjon skal være relevant og pålitelig, men det vil alltid være skjønn forbundet med verdsettelsen.Usaklig skjønn omtales som resultatjustering (”Earnings management”) og regnskaps-manipulasjon. Det er store metodeproblemer innen ”earnings management” – forskningen, da den aktive tilpasningen i stor grad er skjult. I de senere år har ulike modeller for estimering av unormale tidsavgrensninger (”discretionary accruals”) dominert. Problemet er i å estimere de normale tidsavgrensni...

  14. Planretningslinjer for en differensiert forståelse av byggeforbudet i strandsonen erfart av tre kommuner

    OpenAIRE

    Alvheim, Maren

    2014-01-01

    I plan- og bygningsloven er det nå delvis videreført og innstrammet et unntak fra byggeforbudet for å ta hensyn til variasjonene mellom landets kystkommuner. Unntaket innebærer at kommunene må fastsette en ny byggegrense gjennom plan for å fravike forbudet mot bygging i strandsonen. Statlige planretningslinjer for differensiert forvaltning av strandsonen langs sjøen (SPR) er iverksatt med mål om å tydeliggjøre kommunenes adgang til å bygge i strandsonen gjennom plan. Oppgaven søker å avklare ...

  15. AV Rising: Demand, Budgets, and Circulation Are All Up.

    Science.gov (United States)

    Oder, Norman

    1998-01-01

    A survey of 486 public libraries found that audiovisual (AV) budgets have increased 53% in the last five years. Provides data on average size of AV collections; budget break downs; circulation; audiobook, video, and music CD purchases; popular authors and titles in abridged and unabridged audiobooks; and problems with audiobook, video, and music…

  16. Quantification of Tau Load Using [F-18]AV1451 PET

    NARCIS (Netherlands)

    Golla, Sandeep S. V.; Timmers, Tessa; Ossenkoppele, Rik; Groot, Colin; Verfaillie, Sander; Scheltens, Philip; van der Flier, Wiesje M.; Schwarte, Lothar; Mintun, Mark A.; Devous, Michael; Schuit, Robert C.; Windhorst, Albert D.; Lammertsma, Adriaan A.; Boellaard, Ronald; van Berckel, Bart N. M.; Yaqub, Maqsood

    2017-01-01

    The tau tracer [F-18]AV1451, also known as flortaucipir, is a promising ligand for imaging tau accumulation in Alzheimer's disease (AD). Most of the previous studies have quantified tau load using standardized uptake value ratios (SUVr) derived from a static [F-18]AV1451 scan. SUVr may, however, be

  17. EST Table: AV398539 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV398539 NV021929 11/12/09 GO hit GO:0005622(intracellular)|GO:0008270(zinc ion bin...0769|gb|EEZ97216.1| hypothetical protein TcasGA2_TC011009 [Tribolium castaneum] AV398539 NV02 ...

  18. Tissue and cell tropism of Indian cassava mosaic virus (ICMV) and its AV2 (precoat) gene product

    International Nuclear Information System (INIS)

    Rothenstein, Dirk; Krenz, Bjoern; Selchow, Olaf; Jeske, Holger

    2007-01-01

    In order to establish defined viruses for challenging plants in resistance breeding programmes, Indian cassava mosaic virus (ICMV; family Geminiviridae) DNA clones were modified to monitor viral spread in plants by replacing the coat protein gene with the green fluorescent protein (GFP) reporter gene. Comparative in situ hybridization experiments showed that ICMV was restricted to the phloem in cassava and tobacco. GFP-tagged virus spread similarly, resulting in homogeneous fluorescence within nuclei and cytoplasm of infected cells. To analyze viral intercellular transport in further detail, GFP was fused to AV2, a protein that has been implicated in viral movement. Expressed from replicating viruses or from plasmids, AV2:GFP became associated with the cell periphery in punctate spots, formed cytoplasmic as well as nuclear inclusion bodies, the latter as conspicuous paired globules. Upon particle bombardment of expression plasmids, AV2:GFP was transported into neighboring cells of epidermal tissues showing that the intercellular transport of the AV2 protein is not restricted to the phloem. The results are consistent with a redundant function of ICMV AV2 acting as a movement protein, presumably as an evolutionary relic of a monopartite geminivirus that may still increase virus fitness but is no longer necessary in a bipartite genome. The fusion of ICMV ORF AV2 to the GFP gene is the first example of a reporter construct that follows the whole track of viral DNA from inside the nucleus to the cell periphery and to the next cell

  19. Tissue and cell tropism of Indian cassava mosaic virus (ICMV) and its AV2 (precoat) gene product.

    Science.gov (United States)

    Rothenstein, Dirk; Krenz, Björn; Selchow, Olaf; Jeske, Holger

    2007-03-01

    In order to establish defined viruses for challenging plants in resistance breeding programmes, Indian cassava mosaic virus (ICMV; family Geminiviridae) DNA clones were modified to monitor viral spread in plants by replacing the coat protein gene with the green fluorescent protein (GFP) reporter gene. Comparative in situ hybridization experiments showed that ICMV was restricted to the phloem in cassava and tobacco. GFP-tagged virus spread similarly, resulting in homogeneous fluorescence within nuclei and cytoplasm of infected cells. To analyze viral intercellular transport in further detail, GFP was fused to AV2, a protein that has been implicated in viral movement. Expressed from replicating viruses or from plasmids, AV2:GFP became associated with the cell periphery in punctate spots, formed cytoplasmic as well as nuclear inclusion bodies, the latter as conspicuous paired globules. Upon particle bombardment of expression plasmids, AV2:GFP was transported into neighboring cells of epidermal tissues showing that the intercellular transport of the AV2 protein is not restricted to the phloem. The results are consistent with a redundant function of ICMV AV2 acting as a movement protein, presumably as an evolutionary relic of a monopartite geminivirus that may still increase virus fitness but is no longer necessary in a bipartite genome. The fusion of ICMV ORF AV2 to the GFP gene is the first example of a reporter construct that follows the whole track of viral DNA from inside the nucleus to the cell periphery and to the next cell.

  20. Cofactor requirement of HpyAV restriction endonuclease.

    Directory of Open Access Journals (Sweden)

    Siu-Hong Chan

    Full Text Available BACKGROUND: Helicobacter pylori is the etiologic agent of common gastritis and a risk factor for gastric cancer. It is also one of the richest sources of Type II restriction-modification (R-M systems in microorganisms. PRINCIPAL FINDINGS: We have cloned, expressed and purified a new restriction endonuclease HpyAV from H. pylori strain 26695. We determined the HpyAV DNA recognition sequence and cleavage site as CCTTC 6/5. In addition, we found that HpyAV has a unique metal ion requirement: its cleavage activity is higher with transition metal ions than in Mg(++. The special metal ion requirement of HpyAV can be attributed to the presence of a HNH catalytic site similar to ColE9 nuclease instead of the canonical PD-X-D/EXK catalytic site found in many other REases. Site-directed mutagenesis was carried out to verify the catalytic residues of HpyAV. Mutation of the conserved metal-binding Asn311 and His320 to alanine eliminated cleavage activity. HpyAV variant H295A displayed approximately 1% of wt activity. CONCLUSIONS/SIGNIFICANCE: Some HNH-type endonucleases have unique metal ion cofactor requirement for optimal activities. Homology modeling and site-directed mutagenesis confirmed that HpyAV is a member of the HNH nuclease family. The identification of catalytic residues in HpyAV paved the way for further engineering of the metal binding site. A survey of sequenced microbial genomes uncovered 10 putative R-M systems that show high sequence similarity to the HpyAV system, suggesting lateral transfer of a prototypic HpyAV-like R-M system among these microorganisms.

  1. Cofactor requirement of HpyAV restriction endonuclease.

    Science.gov (United States)

    Chan, Siu-Hong; Opitz, Lars; Higgins, Lauren; O'loane, Diana; Xu, Shuang-Yong

    2010-02-05

    Helicobacter pylori is the etiologic agent of common gastritis and a risk factor for gastric cancer. It is also one of the richest sources of Type II restriction-modification (R-M) systems in microorganisms. We have cloned, expressed and purified a new restriction endonuclease HpyAV from H. pylori strain 26695. We determined the HpyAV DNA recognition sequence and cleavage site as CCTTC 6/5. In addition, we found that HpyAV has a unique metal ion requirement: its cleavage activity is higher with transition metal ions than in Mg(++). The special metal ion requirement of HpyAV can be attributed to the presence of a HNH catalytic site similar to ColE9 nuclease instead of the canonical PD-X-D/EXK catalytic site found in many other REases. Site-directed mutagenesis was carried out to verify the catalytic residues of HpyAV. Mutation of the conserved metal-binding Asn311 and His320 to alanine eliminated cleavage activity. HpyAV variant H295A displayed approximately 1% of wt activity. Some HNH-type endonucleases have unique metal ion cofactor requirement for optimal activities. Homology modeling and site-directed mutagenesis confirmed that HpyAV is a member of the HNH nuclease family. The identification of catalytic residues in HpyAV paved the way for further engineering of the metal binding site. A survey of sequenced microbial genomes uncovered 10 putative R-M systems that show high sequence similarity to the HpyAV system, suggesting lateral transfer of a prototypic HpyAV-like R-M system among these microorganisms.

  2. Specialized treatment for Avoidant personality disorder (AvPD): Treatment rationales and preliminary results

    DEFF Research Database (Denmark)

    Simonsen, Sebastian

    and preliminary results from a specialized psychotherapy program developed for patients with AvPD treated at Stolpegaard Psychotherapy Centre, Capital Region of Denmark. Methods: Treatment consists of individual therapy based on Metacognitive Interpersonal Therapy (MIT) while group therapy is a modified form......½-years of therapy. We focus on how patients change in regards to important outcomes, including both acute symptoms and more personality based problems such as self-reflection, interpersonal problems and ability to describe feelings. Conclusions: Consistency of results with regard to theories about Av...... naturalistic study, we followed patients from start to end of psychotherapy on a range of self-report measures including the SCL-90-R, IIP-C, SIPP-118 and TAS-20. Results: In this preliminary report, we report findings from various time points of therapy: Baseline, 6 months, 12 months and after approximately 1...

  3. En undersökning av Norwegians kriskommunikation under flygstrejken 2015. : En textanalys av Facebookinlägg och pressmeddelanden.

    OpenAIRE

    Emma, Mickelsson

    2016-01-01

    Numera lever vi i ett krissamhälle där vi nästan varje dag nås av budskap från olika typer av kriser. När en organisation drabbas av en kris är det viktigt att tänka på vilken kommunikation man använder för att nå ut med sitt budskap. Uppsatsens syfte var att undersöka hur en organisation använder sig av olika försvarsstrategier och retoriska appeller i sin kriskommunikation. Organisationen som valdes ut var flygbolaget Norwegian och deras hantering av den 11 dagar långa flygs...

  4. Kopiering av tradisjonskunst som læringsmetode

    Directory of Open Access Journals (Sweden)

    Mari Rorgemoen

    2011-07-01

    Full Text Available Artikkelen er skriven på bakgrunn av problematikk kring utvikling av ein forskingsbasert didaktikk for tekstilundervisninga på grunnstudiet ved Institutt for folkekultur, Høgskolen i Telemark. Delar av forskingsprosjektet tek difor utgangspunkt i eksisterande undervisnings­verksemd ved dette studiet. Spørsmåla som det er søkt å få svar på her, er: Kva dialog og læri­ng er framtredande ved kopiering av ein tradisjonell tekstilgjenstand? og: Korleis har denne arbeidsmåten ein plass i ein forskingsbasert didaktikk? Kopiprosessen skjedde i ein avgrensa oppgåveperiode, utført med to studentgrupper i 2008/2009. Intervju var valt som me­to­de saman med analyse av innhald i oppgåverapportar som var skrivne samtidig med kopiverksemda. I samband med utvikling av ein forskingsbasert didaktikk der kopiverksemd inngår, er drøftingane førte på grunnlag av sosiokulturell og sløydpedagogisk teori, saman med teori i møte med folkekunst. Kopiprosessen er relatert til ein verksemdsmodell for sløydfaget. Resultata er drøfta i høve til mål for oppgåva og gjeldande fagplan. Kopiering som læringsmetode har ein plass i ein forskingsbasert didaktikk når verksemda fører til erkjenning og integrert forståing, ikkje som rekonstruksjon av tradisjonar. Målet for ein forsk­ings­­basert didaktikk er horisontsamansmelting som følgje av hermeneutiske samtaler som gjeld samspel, spatialitet, spelereglar og spelerom i tradisjonen.

  5. Matglede hos barn : effekter av et læringsprogram

    OpenAIRE

    Myhrer, Kristine Svartebekk

    2013-01-01

    SAMMENDRAG Bakgrunnen for denne studien var Nasjonalt råd for ernærings nye kostholdsråd for den norske befolkningen. I rådene er det anbefalt å begrense inntaket av rødt kjøtt, bearbeidet kjøtt, salt, sukker og mettet fett for å forebygge kroniske kostrelaterte sykdommer i befolkningen, slik som diabetes og overvekt. For å påvirke barns valg av mat mot et sunnere kosthold er det behov for å forstå faktorer som kan påvirke barnas valg og aksept av matvarer Formålet med masteroppgaven e...

  6. A case of pancreatic AV malformation in an elderly man.

    Science.gov (United States)

    Gupta, Vipin; Kedia, Saurabh; Sonika, Ujjwal; Madhusudhan, Kumble Seetharama; Pal, Sujoy; Garg, Pramod

    2018-02-05

    A 60-year-old man presented with recurrent abdominal pain and weight loss for 6 months. Abdominal imaging showed a large vascular lesion in the head and neck of pancreas suggestive of arteriovenous malformation (AV malformation). Endoscopic ultrasound was done which showed features of AV malformation with no evidence of pancreatic malignancy. Surgery was planned for definitive treatment of malformation. Digital subtraction angiography with angioembolization was done prior to surgery to reduce vascularity of the lesion. He recovered after a pylorus preserving pancreaticoduodenectomy. Histopathology of the resected specimen confirmed the pancreatic AV malformation. There has been no recurrence at 2 years of follow-up.

  7. Grekisk mytologi i The Lightning Thief av Rick Riordan

    OpenAIRE

    Liu, Olivia

    2017-01-01

    Syftet med denna undersökning är att genom en komparativ studie med utgångspunkt i teorier om dialogicitet, hyptertextualitet och transformation, analysera förekomsten av grekisk mytologi i The Lightning Thief (2005) – vilken påverkan dessa har och hur de tar sig uttryck i Riordans roman. De grekiska myterna i The Lightning Thief har jämförts med de som beskrivs i Grekisk Mytologi (1977) av Giovanni Caselli och Michael Gibson, En introduktion till grekisk mytologi (1989) av David Bellingham, ...

  8. Catheter ablation of pediatric AV nodal reentrant tachycardia: results in small children.

    Science.gov (United States)

    Krause, Ulrich; Backhoff, David; Klehs, Sophia; Kriebel, Thomas; Paul, Thomas; Schneider, Heike E

    2015-11-01

    AV nodal reentrant tachycardia (AVNRT) is commonly encountered in pediatric patients. Definite treatment can be achieved by catheter ablation. The purpose of the study was to evaluate the efficacy and safety of AVNRT ablation focusing on children with a body weight ≤25 kg. Catheter ablation of AVNRT was attempted in 253 patients. Median age was 12.5 years; median body weight was 48.7 kg. 25 (9.9 %) children had a body weight ≤25 kg. Congenital heart disease was present in 6 patients (2.4 %). Procedural success was achieved in 98 % using radiofrequency, in 100 % using cryoenergy alone, and in 94 % using both energy sources. In patients with a body weight ≤25 kg, success was achieved in 96 %. In patients ≤25 kg, fluoroscopy and procedure duration did not differ from those >25 kg. The rate of major complications was significantly higher in the patients ≤25 kg (12 vs. 2.2 %, p = 0.04). Permanent AV block after RF ablation occurred in 2 patients with congenital heart disease and one infant with a body weight of 8.7 kg. Catheter ablation of AVNRT in children and adolescents was safe and effective. Infants and small children with a body weight ≤25 kg had a higher prevalence of serious complications. This should alert physicians in decision making toward catheter ablation in these patients. In patients with congenital heart disease and different anatomy of the cardiac conduction system, operators must be aware of an increased risk for AV block.

  9. Turbulens? - Norske nettavisers omtale av Norwegian 2013. [En kvantitativ innholdsanalyse av VG, DB, Aftenposten, NRK og DNs dekning av Norwegians Dreamliner-kjøp

    OpenAIRE

    Knudsen, Anders

    2015-01-01

    Analysen tar for seg omtale av flyselskapet Norwegian i de fem norske nettavisene VG.no, DB.no, Aftenposten.no, NRK.no og DN.no. Prosjektet fokuserer på artiklenes vinkling og hvordan selskapet omtales i forbindelse med Dreamliner-skandalen, med utgangspunkt i dagsordenfunksjonen og teorien om framing. For å belyse dette har jeg tatt utgangspunkt i følgende problemstilling: Hvordan vinklet og fokuserte norske nettaviser i 2013 på Norwegians kjøp og innføring av nye Dre...

  10. Ultrasound guided supraclavicular block.

    LENUS (Irish Health Repository)

    Hanumanthaiah, Deepak

    2013-09-01

    Ultrasound guided regional anaesthesia is becoming increasingly popular. The supraclavicular block has been transformed by ultrasound guidance into a potentially safe superficial block. We reviewed the techniques of performing supraclavicular block with special focus on ultrasound guidance.

  11. Navy AV-8B Crash Survivable Flight Incident Recorder (CSFIR)

    National Research Council Canada - National Science Library

    1998-01-01

    ...) met at the Naval Air Weapons Development Center, Building P302, China Lake, CA for a Program Review I Technical Interchange Meeting in support of the AV-8B Crash Survivable Flight Incident Recorder System (CSFIR...

  12. Open Source AV solution supporting In Situ Simulation

    DEFF Research Database (Denmark)

    Krogh, Kristian; Pociunas, Gintas; Dahl, Mads Ronald

    the software to meet our expectations for a portable AV system for VAD. The system would make use of “off the shelf” hardware components which are widely available and easily replaced or expanded. The developed AV software and coding is contracted to be available as Copyleft Open Source to ensure low cost...... a stable AV software that has be developed and implemented for an in situ simulation initiative. This version (1.3) is the first on released as Open Source (Copyleft) software (see QR tag). We have found that it is possible to deliver multi-camera video assisted debriefing in a mobile, in situ simulation...... environment using an AV system constructed from “off the shelf” components and Open Source software....

  13. Knihovna Sociologického ústavu AV ČR

    Czech Academy of Sciences Publication Activity Database

    Hesová, Nela

    2017-01-01

    Roč. 7, č. 3 (2017) E-ISSN 1805-2800 Institutional support: RVO:68378025 Keywords : library Subject RIV: AF - Documentation, Librarianship, Information Studies https://www.lib.cas.cz/casopis-informace/knihovna-sociologickeho-ustavu-av-cr/

  14. Kinetics of block-copolymer aggregation in supercritical CO2

    Czech Academy of Sciences Publication Activity Database

    Triolo, A.; Lo Celso, F.; Triolo, F.; Amenitsch, H.; Steinhart, Miloš; Thiyagarajan, P.; Wells, S.; DeSimone, J. M.; Triolo, R.

    2002-01-01

    Roč. 307, - (2002), s. 725-730 ISSN 0022-3093 R&D Projects: GA AV ČR KSK4050111 Keywords : block copolymers * X-ray scattering * small-angle Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.435, year: 2002

  15. Congenital Complete Atrioventricular Block : Clinical and Experimental Studies

    NARCIS (Netherlands)

    Blank, A.C.

    2014-01-01

    Complete atrioventricular block (CAVB) is a cardiac conduction defect wherein the trans¬mission of the normal electrical impulse from the atria to the ventricle is interrupted due to structural or functional impairment of the atrioventricular (AV) conduction system. If CAVB is diagnosed in utero or

  16. Functionalized alkoxy tin clusters as nanobuilding blocks for hybrid materials

    Czech Academy of Sciences Publication Activity Database

    Martinez-Ferrero, E.; Ribot, F.; Rozes, L.; Sanchez, C.; Matějka, Libor

    2005-01-01

    Roč. 33, 2-4 (2005), s. 89-97 ISSN 0079-6786 Grant - others:European Community Human Potential Program HPRN-CT-2002-00306 Institutional research plan: CEZ:AV0Z40500505 Keywords : tin clusters * polymer hybrids * nanobuilding blocks Subject RIV: CD - Macromolecular Chemistry Impact factor: 15.167, year: 2005

  17. EST Table: AV404029 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV404029 pg--0356 11/12/09 n.h 10/09/28 99 %/103 aa ref|YP_003044625.1| hypothetica...n ECD_01416 [Escherichia coli BL21(DE3)] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV404029 pg-- ...

  18. EST Table: AV404052 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV404052 pg--0383 10/09/28 90 %/146 aa ref|YP_002386254.1| Major tail protein V [Es...cherichia coli IAI1] emb|CAQ97657.1| Major tail protein V [Escherichia coli IAI1] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV404143 pg-- ...

  19. EST Table: AV403989 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403989 pg--0306 10/09/28 100 %/137 aa ref|NP_037751.1| Q protein [Enterobacteria ...phage HK97] gb|AAF31144.1| Q protein [Enterobacteria phage HK97] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV404408 pg-- ...

  20. EST Table: AV399390 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV399390 NV120162 11/12/09 n.h 10/09/28 100 %/181 aa ref|YP_002884244.1| Ac13-like ...yhedrovirus] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV399390 NV12 ...

  1. Hyperkalemia-induced complete heart block

    Directory of Open Access Journals (Sweden)

    Alireza Baratloo

    2015-05-01

    Full Text Available Background: Potassium, as an extracellular ion, plays an important role in the electrophysiologic function of the myocardium and any change in extracellular concentration of this ion might have a marked impression upon myocyte electrophysiologic gain. High serum potassium levels are thought to impair pulse conduction in Purkinje fibers and ventricles more than that in the Atrioventricular (AV node. Therefore, although complete AV block can occur, it is a rare initial presentation. Case Report: We describe a 62-year-old man with a history of diabetes mellitus, ischemic heart disease and previous Coronary Artery Bypass Graft (CABG, who came to our emergency department due to generalized weakness starting 2 days before admission. The patient also had decreased force in lower limbs, exacerbating from the morning, and was finally diagnosed as a hyperkalemia-induced Complete Heart Block (CHB. It should also be noted that the patient responded dramatically to the administration of 10 mL of 10% calcium gluconate along with external pacing until potassium level correction became effective. Conclusion: In spite of the fact that Hyperkalemia can be associated with frequent Electrocardiogram (ECG abnormality, advanced heart blocks (second- and third-degree AV blocks are usually found only in patients with pre-existing heart failure, conduction abnormalities, or other cardiac diseases. Institution of effective treatment rapidly and forgiveness of traditional non-effective, time consumptive and sometimes risking full-adjustment modalities, such as sodium bicarbonate infusion or exchange resins that prevent their use in the emergent phase, can help minimize patient morbidity and mortality.

  2. Transvenous cold mapping and cryoablation of the AV node in dogs: observations of chronic lesions and comparison to those obtained using radiofrequency ablation

    NARCIS (Netherlands)

    Rodriguez, L. M.; Leunissen, J.; Hoekstra, A.; Korteling, B. J.; Smeets, J. L.; Timmermans, C.; Vos, M.; Daemen, M.; Wellens, H. J.

    1998-01-01

    Radiofrequency (RF) is the most commonly used energy source for the treatment of cardiac arrhythmias. Surgical experience has shown that cryoablation also is effective for ablating arrhythmias. The aims of this study were to (1) investigate the feasibility of inducing permanent complete AV block

  3. Reversible complete atrioventricular block in patient with wegener's granulomatosis - a report on fortunate outcome with long term follow-up.

    Science.gov (United States)

    Steckiewicz, Roman; Rosiak, Marek; Stolarz, Przemysław; Świętoń, Elżbieta B; Grabowski, Marcin; Kosior, Dariusz A

    Reversible complete atrioventricular block in patient with Wegener's granulomatosis - a report on a positive outcome with long term follow-up. Atrioventricular (AV) block is a rare complication of Wegener's granulomatosis (WG), thus there are no standards of management in such cases. We present a case of a patient with a dual-chamber pacemaker (DDD) implanted due to complete AV block in the course of Wegener's granulomatosis (WG). An immunosuppressive therapy resulted in the resolution of non-cardiac and AV conduction disorders. The diagnostic functions of the pacemaker enabled us to evaluate AV conduction over a five-year follow-up period. The resolution of AV conduction disorders, which accompanied WG remission, suggests that careful monitoring with temporary cardiac pacing may be considered in some patients before permanent pacemaker implantation.

  4. Cardiac resynchronization therapy and AV optimization increase myocardial oxygen consumption, but increase cardiac function more than proportionally☆

    Science.gov (United States)

    Kyriacou, Andreas; Pabari, Punam A.; Mayet, Jamil; Peters, Nicholas S.; Davies, D. Wyn; Lim, P. Boon; Lefroy, David; Hughes, Alun D.; Kanagaratnam, Prapa; Francis, Darrel P.; I.Whinnett, Zachary

    2014-01-01

    Background The mechanoenergetic effects of atrioventricular delay optimization during biventricular pacing (“cardiac resynchronization therapy”, CRT) are unknown. Methods Eleven patients with heart failure and left bundle branch block (LBBB) underwent invasive measurements of left ventricular (LV) developed pressure, aortic flow velocity-time-integral (VTI) and myocardial oxygen consumption (MVO2) at 4 pacing states: biventricular pacing (with VV 0 ms) at AVD 40 ms (AV-40), AVD 120 ms (AV-120, a common nominal AV delay), at their pre-identified individualised haemodynamic optimum (AV-Opt); and intrinsic conduction (LBBB). Results AV-120, relative to LBBB, increased LV developed pressure by a mean of 11(SEM 2)%, p = 0.001, and aortic VTI by 11(SEM 3)%, p = 0.002, but also increased MVO2 by 11(SEM 5)%, p = 0.04. AV-Opt further increased LV developed pressure by a mean of 2(SEM 1)%, p = 0.035 and aortic VTI by 4(SEM 1)%, p = 0.017. MVO2 trended further up by 7(SEM 5)%, p = 0.22. Mechanoenergetics at AV-40 were no different from LBBB. The 4 states lay on a straight line for Δexternal work (ΔLV developed pressure × Δaortic VTI) against ΔMVO2, with slope 1.80, significantly > 1 (p = 0.02). Conclusions Biventricular pacing and atrioventricular delay optimization increased external cardiac work done but also myocardial oxygen consumption. Nevertheless, the increase in cardiac work was ~ 80% greater than the increase in oxygen consumption, signifying an improvement in cardiac mechanoenergetics. Finally, the incremental effect of optimization on external work was approximately one-third beyond that of nominal AV pacing, along the same favourable efficiency trajectory, suggesting that AV delay dominates the biventricular pacing effect — which may therefore not be mainly “resynchronization”. PMID:24332598

  5. Homogeneous bilateral block shifts

    Indian Academy of Sciences (India)

    Douglas class were classified in [3]; they are unilateral block shifts of arbitrary block size (i.e. dim H(n) can be anything). However, no examples of irreducible homogeneous bilateral block shifts of block size larger than 1 were known until now.

  6. Light scattering from block copolymer melts near the order-disorder transition

    Czech Academy of Sciences Publication Activity Database

    Štěpánek, Petr; Lodge, T. P.; Bates, F. S.

    1994-01-01

    Roč. 2, - (1994), s. 110 ISSN 0009-2347. [Symposium Block Copolymer Dynamics, Chain Dynamics of Block Copolymers: Dynamics near the Ordering Transition. San Diego, 13.03.1994-18.03.1994] R&D Projects: GA AV ČR IA45023 Impact factor: 0.331, year: 1994

  7. Radiotherapy as a cause of complete atrioventricular block in Hodgkin's disease: an electrophysiological-pathological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, S.I.; Bharati, S.; Glass, J.; Lev, M.

    1981-04-01

    A 20-year-old man contracted Hodgkin's disease and was treated with mantle radiotherapy. Heart block developed 11 years later. Electrocardiograms revealed predominant atrioventricular (AV) block and occasional AV conduction. Intracardiac electrograms demonstrated that the site of AV block was above the level of the His bundle. A permanent transvenous pacemaker was implanted. Seven months later the patient died of complications from cryptococcal meningitis. Pathological study of the heart revealed marked arteriosclerosis with fibrosis of the epicardium, myocardium, and endocardium. Examination of the conduction system revealed extensive arteriolosclerosis of the sinoatrial node and its approaches. In addition, there was marked fibrosis of the approaches to the AV node, the AV bundle, and both bundle branches. There was no evidence of Hodgkin's disease. This case documents the rare occurrence of AV block due to tissue destruction by radiotherapy. There was a good correlation between block proximal to the His bundle recording site and fibrosis of the approaches to the AV node.

  8. Radiotherapy as a cause of complete atrioventricular block in Hodgkin's disease. An electrophysiological-pathological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, S.I.; Bharati, S.; Glass, J.; Lev, M.

    1981-04-01

    A 20-year-old man contracted Hodgkin's disease and was treated with mantle radiotherapy. Heart block developed 11 years later. Electrocardiograms revealed predominant atrioventricular (AV) block and occasional AV conduction. Intracardiac electrograms demonstrated that the site of AV block was above the level of the His bundle. A permanent transvenous pacemaker was implanted. Seven months later the patient died of complications from cryptococcal meningitis. Pathological study of the heart revealed marked arteriosclerosis with fibrosis of the epicardium, myocardium, and endocardium. Examination of the conduction system revealed extensive arteriolosclerosis of the sinoatrial node and its approaches. In addition, there was marked fibrosis of the approaches to the AV node, the AV bundle, and both bundle branches. There was no evidence of Hodgkin's disease. This case documents the rare occurrence of AV block due to tissue destruction by radiotherapy. There was a good correlation between block proximal to the His bundle recording site and fibrosis of the approaches to the AV node.

  9. Occurrence of atrioventricular block during supraventricular tachycardia: What is its possible mechanism?

    Directory of Open Access Journals (Sweden)

    Ho-Shun Cheng

    2014-02-01

    Full Text Available A female patient was admitted to our hospital for catheter ablation arising from paroxysmal supraventricular tachycardia (PSVT. In the laboratory, PSVT (the earliest retrograde atrial activation at the coronary sinus ostium with intermittent atrioventricular (AV block could be induced repeatedly. The tachycardia could be terminated during ventricular pacing without retrograde conduction to the atria. Therefore, orthodromic AV reciprocating tachycardia (AVRT and atrial tachycardia (AT could be ruled out and AV nodal re-entrant tachycardia (AVNRT was subsequently considered. Initial attempts using slow or intermediate AV nodal ablation failed to cure the tachycardia. We considered the possibility of orthodromic AV reciprocating tachycardia (AVRT with AV block occurring during the tachycardia. The tachycardia was successfully terminated during the ablation of the right posteroseptal pathway at the coronary sinus ostium. We hypothesized about the possible explanation that might help to clarify the phenomenon of AV block during SVT in order to provide some guidance to other clinicians confronted with similar patient challenges in the future.

  10. The role of AV and VV optimization for CRT

    Directory of Open Access Journals (Sweden)

    William W. Brabham, M.D.

    2013-06-01

    Full Text Available Cardiac resynchronization therapy is an effective therapy for patients with left ventricular systolic dysfunction and a ventricular conduction delay; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. Modern devices allow individualized programming of the AV delay and VV offset, which offer the possibility of improving clinical response rates with optimized programming. AV and VV delay optimization techniques have included echocardiography, device-based algorithms, and several other novel noninvasive techniques. While an acute improvement in hemodynamic function has been clearly demonstrated with optimized device settings, long-term clinical benefit is limited. In the majority of cases, an empiric AV delay with simultaneous biventricular or left ventricular pacing is adequate. The value of optimization of these intervals in “non-responders” still requires further investigation.

  11. [Acute atrio-ventricular block in sickle cell anemia].

    Science.gov (United States)

    Gacon, P-H; Jourdain, P; Heba, N; Amara, W

    2014-11-01

    Even though sickle cell disease has a high prevalence amongst the black race and despite its well known potential of micro infarction, there have been only a few reports regarding the acute myocardial damage during vaso-occlusive crisis. The risk of atrio ventricular block during these crises has never been described in a large survey. Ten patients (six men and four women, mean age 39 years old) were hospitalized for an acute atrio ventricular block. The patients were all African or Caribbean natives. Three patients were found with a heterozygous phenotype for hemoglobin S (sickle trait) and seven were found with a homozygous phenotype. The most common symptoms were asthenia (10 cases), shortness of breath (8 cases) and acute coronary syndrome (1 case) (syncope was not reported). Four patients had a second degree atrio ventricular block and six patients had third degree block. The treatment involved bed rest, intravenous hydration, and pain relief with opiates. All the cases of atrio ventricular block were only transitory and none of the patients underwent a pacemaker implantation. This report is the largest survey regarding transitory acute atrio ventricular block in patients with sickle cell disease. A local ischemic event affecting the AV node and Hiss bundle area can explain the conduction abnormalities. Sickle cell disease must be ruled out in black patients with an AV block. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  12. Light Scattering, Atomic Force Microscopy and Fluorescence Correlation Spectroscopy Studies of Polystyrene-block-poly(2-vinylpyridine)-block-poly(ethylene oxide) Micelles

    Czech Academy of Sciences Publication Activity Database

    Štěpánek, M.; Humpolíčková, J.; Procházka, K.; Hof, Martin; Tuzar, Zdeněk; Špírková, Milena; Wolff, T.

    2003-01-01

    Roč. 68, č. 10 (2003), s. 2120-2138 ISSN 0010-0765 R&D Projects: GA MŠk LN00A032; GA ČR GA203/01/0536; GA ČR GA203/01/0735 Institutional research plan: CEZ:AV0Z4050913; CEZ:AV0Z4040901 Keywords : block copolymer micelles * water-soluble polymers * polystyrene Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 1.041, year: 2003

  13. Brachial artery aneurysms following brachio-cephalic AV fistula ligation.

    Science.gov (United States)

    Khalid, Usman; Parkinson, Frances; Mohiuddin, Kamran; Davies, Paula; Woolgar, Justin

    2014-01-01

    Peripheral artery aneurysms proximal to a long-standing arteriovenous (AV) fistula can be a serious complication. It is important to be aware of this and manage it appropriately. Vascular access nurses input all data regarding patients undergoing dialysis access procedures into a securely held database prospectively. This was retrospectively reviewed to identify cases of brachial artery aneurysms over the last 3 years. In Morriston Hospital, around 200 forearm and arm AV fistulas are performed annually for vascular access in renal dialysis patients. Of these, approximately 15 (7.5%) are ligated. Three patients who had developed brachial artery aneurysms following AV fistula ligation were identified. All 3 patients had developed brachial artery aneurysms following ligation of a long-standing brachio-cephalic AV fistula. Two patients presented with pain and a pulsatile mass in the arm, and one presented with pins and needles and discoloration of fingertips. Two were managed with resection of the aneurysm and reconstruction with a reversed long saphenous vein interposition graft, the third simply required ligation of a feeding arterial branch. True aneurysm formation proximal to an AV fistula that has been ligated is a rare complication. There are several reasons for why these aneurysms develop in such patients, the most plausible one being the increase in blood flow and resistance following ligation of the AV fistula. Of note, all the patients in this study were on immunosuppressive therapy following successful renal transplantation. Vigilance by the vascular access team and nephrologists is paramount to identify those patients who may warrant further evaluation and investigation by the vascular surgeon.

  14. Lesing av delvis motstridende tekster i syvende klasse

    Directory of Open Access Journals (Sweden)

    Wenke Mork Rogne

    2013-06-01

    Full Text Available I denne artikkelen ser vi på hvilken type informasjon elever i 7. klasse vektlegger for å konstruere en sammenhengende oppsummering av fire til dels motstridende tekster. Elever møter ofte flere tekster om samme tema – multiple tekster – og vi trenger økt kunnskap om hvordan de leser slike tekster. Elevene leste fire ulike tekster om en sykkelulykke. Tekstene presenterte informasjon som var delvis sammenfallende på tvers av alle tekstene, og delvis motstridende informasjon som innebar at enkelte tekster ga ulike beskrivelser av hendelsesforløpet. Vi testet elevenes ordavkodingsferdigheter, fikk dem til å fylle ut et spørreskjema om lesevaner og vi innhentet elevenes resultater på Nasjonal leseprøve. Etter lesing ba vi elevene gi en oppsummering av sykkelulykken. Elevene gjenga relativt mer sammenfallende informasjon enn motstridende informasjon. Gode resultater på Nasjonal leseprøve ser ut til å ha en sammenheng med elevenes ferdigheter i å konstruere en sammenhengende forståelse av de fire tekstene. Elever som oppga å lese mye på Internett hadde imidlertid fått med mindre av informasjonen som var felles for de fire tekstene i sine oppsummeringer. Vi fant også en negativ sammenheng mellom fritidslesing på Internett og resultatene fra Nasjonal leseprøve. Samlet sett indikerer resultatene at når elevene skal skape sammenheng mellom flere delvis motstridende tekster, så blir sammenfallende informasjon vektlagt mer enn motstridende informasjon. Dessuten ser det ut til at de elevene som bruker mest fritid til å lese på Internett, sliter mer med å sammenfatte innholdet i de fire tekstene enn de andre elevene.

  15. Högstadieelevers upplevelse av sex- och samlevnadsundervisning : en intervjustudie

    OpenAIRE

    Ejder, Alina; Karlsson, Sanna

    2016-01-01

    En god sex- och samlevnadsundervisning i skolan är central för att ha möjlighet att utveckla en god hälsa, vilken dock enligt tidigare forskning har visats vara av bristande kvalitet. Syftet med studien är att undersöka högstadieelevers upplevelse av sex- och samlevnadsundervisningen på deras skola, med fokus på pedagog ledda lektioner. Studiens metod var en kvalitativ intervjustudie, där sex högstadieelever intervjuades individuellt. Resultatet visade att eleverna upplevde att undervisningen...

  16. EST Table: AV404040 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV404040 pg--0370 11/12/09 GO hit GO:0006810(transport)|GO:0006865(amino acid trans...e transport) 10/09/28 83 %/164 aa pdb|3L1L|A Chain A, Structure Of Arg-Bound Escherichia Coli Adic 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV404040 pg-- ...

  17. Revisjon av anleggskontrakter i henhold til god revisjonsskikk

    OpenAIRE

    Woxen, Hans Jacob; Feng, Yennie Jie Zhen

    2014-01-01

    Prosjektregnskap må føres når anleggskontrakter foreligger. I de tilfelle disse inneholder vesentlig feilinformasjon, påvirker dette årsregnskapet i tilsvarende grad. Hvordan revisor må revidere for å ivareta kravet til god revisjonsskikk, utgjør problemstillingen som ligger til grunn for denne masteroppgaven. Anleggskontrakter er ifølge IAS 11 kontrakter som er særlig fremforhandlet for tilvirkning av en eiendel eller en kombinasjon av eiendeler. Denne definisjonen utdypes ...

  18. EST Table: AV403981 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available terminase large subunit (DNA packaging protein A) from bacteriophage origin [Escherichia coli UMN026] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h AV403981 pg-- ... ...AV403981 pg--0297 11/12/09 n.h 10/09/28 100 %/265 aa ref|YP_002411376.1| terminase large subunit (DNA packag...ing protein A) from bacteriophage origin [Escherichia coli UMN026] emb|CAR11828.1|

  19. EST Table: AV398396 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV398396 NV021762 11/12/09 GO hit GO:0005622(intracellular)|GO:0008270(zinc ion bin...ding) 10/09/28 n.h 10/08/28 n.h 10/08/27 n.h 10/09/10 30 %/120 aa AGAP003111-PA Protein|2R:32505726:32508690:1|gene:AGAP003111 10/09/10 n.h 10/09/10 n.h AV398396 NV02 ...

  20. Novel inter and intra prediction tools under consideration for the emerging AV1 video codec

    Science.gov (United States)

    Joshi, Urvang; Mukherjee, Debargha; Han, Jingning; Chen, Yue; Parker, Sarah; Su, Hui; Chiang, Angie; Xu, Yaowu; Liu, Zoe; Wang, Yunqing; Bankoski, Jim; Wang, Chen; Keyder, Emil

    2017-09-01

    Google started the WebM Project in 2010 to develop open source, royalty- free video codecs designed specifically for media on the Web. The second generation codec released by the WebM project, VP9, is currently served by YouTube, and enjoys billions of views per day. Realizing the need for even greater compression efficiency to cope with the growing demand for video on the web, the WebM team embarked on an ambitious project to develop a next edition codec AV1, in a consortium of major tech companies called the Alliance for Open Media, that achieves at least a generational improvement in coding efficiency over VP9. In this paper, we focus primarily on new tools in AV1 that improve the prediction of pixel blocks before transforms, quantization and entropy coding are invoked. Specifically, we describe tools and coding modes that improve intra, inter and combined inter-intra prediction. Results are presented on standard test sets.

  1. Etableringen av Tesla Motors på det norske bilmarkedet : en empirisk studie av salgsdrivere og konkurranseeffekter

    OpenAIRE

    Asperheim, Hanne Henjum; Vedum, Anders

    2015-01-01

    Denne masterutredningen er en empirisk studie av Tesla Motors’ etablering på det norske bilmarkedet. Vi gjennomfører to separate analyser: Først fokuseres det på geografiske salgsforskjeller, deretter på effekten Tesla Motors har hatt på det norske nybilmarkedet. I vår første analyse utvikler vi en modell for å identifisere Teslas salgsdrivere, i form av geografiske og sosioøkonomiske variabler. Resultatene viser at et fylkes inntektsnivå, utdanningsnivå og miljøbevissthet har en positiv s...

  2. 18F-AV-1451 positron emission tomography in Alzheimer’s disease and progressive supranuclear palsy

    Science.gov (United States)

    Passamonti, Luca; Vázquez Rodríguez, Patricia; Hong, Young T.; Allinson, Kieren S. J.; Williamson, David; Borchert, Robin J.; Sami, Saber; Cope, Thomas E.; Bevan-Jones, W. Richard; Jones, P. Simon; Arnold, Robert; Surendranathan, Ajenthan; Mak, Elijah; Su, Li; Fryer, Tim D.; Aigbirhio, Franklin I.; O’Brien, John T.; Rowe, James B.

    2017-01-01

    Abstract The ability to assess the distribution and extent of tau pathology in Alzheimer’s disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these tauopathies and clinical trials of disease-modifying therapies. New radioligands for positron emission tomography have generated considerable interest, and controversy, in their potential as tau biomarkers. We assessed the radiotracer 18F-AV-1451 with positron emission tomography imaging to compare the distribution and intensity of tau pathology in 15 patients with Alzheimer’s pathology (including amyloid-positive mild cognitive impairment), 19 patients with progressive supranuclear palsy, and 13 age- and sex-matched controls. Regional analysis of variance and a support vector machine were used to compare and discriminate the clinical groups, respectively. We also examined the 18F-AV-1451 autoradiographic binding in post-mortem tissue from patients with Alzheimer’s disease, progressive supranuclear palsy, and a control case to assess the 18F-AV-1451 binding specificity to Alzheimer’s and non-Alzheimer’s tau pathology. There was increased 18F-AV-1451 binding in multiple regions in living patients with Alzheimer’s disease and progressive supranuclear palsy relative to controls [main effect of group, F(2,41) = 17.5, P AV-1451 binding was significantly increased in patients with Alzheimer’s disease, relative to patients with progressive supranuclear palsy and with control subjects, in the hippocampus and in occipital, parietal, temporal, and frontal cortices (t’s > 2.2, P’s AV-1451 binding was elevated in the midbrain (t = 2.1, P AV-1451 uptake in the putamen, pallidum, thalamus, midbrain, and in the dentate nucleus of the cerebellum (t’s > 2.7, P’s AV-1451 strongly bound to Alzheimer-related tau pathology, but less specifically in progressive supranuclear palsy. 18F-AV-1451 binding to the basal ganglia was strong in all groups in vivo. Postmortem histochemical

  3. EST Table: AV404642 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV404642 prgv0279 10/09/28 81 %/116 aa ref|NP_001091796.1| programmed cell death pr...otein 5-like protein [Bombyx mori] gb|ABJ97180.1| programmed cell death protein 5-like protein [Bombyx mori

  4. The apolipoprotein AV gene and diurnal triglyceridaemia in normolipidaemic subjects

    NARCIS (Netherlands)

    Masana, L; Ribalta, J; Salazar, J; Fernandez-Ballart, J; Joven, J; Cabezas, MC

    2003-01-01

    The newly recognised apolipoprotein (apo) AV gene (APOAV) has been linked to fasting plasma triglyceride (TG) concentrations with some polymorphisms associated with elevated fasting TGs. Since fasting plasma TGs are mainly determined by the hepatic production of TGrich particles (very low density

  5. User guide of AVS/ITBL for numerical environmental system

    International Nuclear Information System (INIS)

    Suzuki, Yoshio; Matsumoto, Nobuko; Yamagishi, Nobuhiro; Arakawa, Takuya; Kuraishi, Hideaki

    2005-02-01

    The Center for Promotion of Computational Science and Engineering of the Japan Atomic Energy Research Institute has carried out the ITBL (Information-Technology Based Laboratory) project which is one of e-Japan priority policy programs. The goal of the ITBL project is to create the vertical research environment in which intellectual resources such as remote computers, programs and data can be shared in Japanese research institutions and cooperative studies among researchers can be supported. AVS/ITBL is the visualization tool which has been developed aiming at realizing the efficient visualization in the ITBL environment. This visualization tool is one of the tools of ITBL infrastructure software and operates in cooperation with AVS/Express. Main functions of AVS/ITBL are as follows: it can directly read data files located on remote computers, it can display and control an image on the web browser, it can collaboratively display an image among remote researchers, and it can perform visualization process as a batch. In this paper, utilization of AVS/ITBL to the numerical environmental system, which is one of the applications in ITBL project, is presented. And the outline of the operation in this utilization is indicated. (author)

  6. Rektorers forståelse av mobbing i skolen

    DEFF Research Database (Denmark)

    Hansen, Helle Rabøl

    2008-01-01

    PÅ opfordring fra redaktionen gives en kommentar med dansk vinkel til den norske artikel 'Rektorers forståelse av mobbning i skolen'.Den omtalte artikel er at betragte som første trin i indførelse af en nordisk mobbeforståelse med undgangspunkt i Dan Olweus begrebsafgrænsning.Der savnes også en i...

  7. Mutagenesis in ORF AV2 affects viral replication in Mungbean ...

    Indian Academy of Sciences (India)

    Mungbean yellow mosaic India virus (MYMIV) is a whitefly-transmitted begomovirus with a bipartite genome. .... 1996) and in Indian cassava mosaic virus (Rothenstein et al. 2007). The ability of AV2 of another bipartite begomovirus, East African cassava mosaic Cameroon virus ...... (New York: WH Freeman and Company).

  8. EST Table: AV403752 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403752 pg--0009 10/09/28 100 %/257 aa ref|YP_002411376.1| terminase large subunit (DNA packaging... protein A) from bacteriophage origin [Escherichia coli UMN026] emb|CAR11828.1| terminase large subunit (DNA packaging

  9. EST Table: AV403922 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403922 pg--0214 10/09/28 91 %/142 aa ref|ZP_06118881.2| DNA packaging protein FI ...[Clostridium hathewayi DSM 13479] gb|EFC94454.1| DNA packaging protein FI [Clostridium hathewayi DSM 13479

  10. EST Table: AV404246 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV404246 pg--0747 10/09/28 91 %/130 aa ref|ZP_06118881.2| DNA packaging protein FI ...[Clostridium hathewayi DSM 13479] gb|EFC94454.1| DNA packaging protein FI [Clostridium hathewayi DSM 13479

  11. EST Table: AV399507 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV399507 NV120319 10/09/28 70 %/144 aa ref|YP_803401.1| baculovirus repeated ORF-b [Anticars...ia gemmatalis nucleopolyhedrovirus] gb|ABI13791.1| baculovirus repeated ORF-b [Anticarsia gemmatali

  12. Imaging of VMAT2 binding sites in the brain by (18)F-AV-133: the effect of a pseudo-carrier.

    Science.gov (United States)

    Zhu, Lin; Qiao, Hongwen; Lieberman, Brian P; Wu, Jingxiao; Liu, Yajing; Pan, Zhongyun; Ploessl, Karl; Choi, Seok Rye; Chan, Piu; Kung, Hank F

    2012-10-01

    Recently, 9-[(18)F]fluoropropyl-(+)-dihydrotetrabenazine ((18)F-AV-133) was reported as a new vesicular monoamine transporter (VMAT2) imaging agent for diagnosis of Parkinson's disease (PD). To shorten the preparation of (18)F-AV-133 and to make it more widely available, we evaluated a simple, rapid purification with a solid-phase extraction method (SPE) using an Oasis HLB cartridge instead of high pressure liquid chromatography (HPLC). The SPE method produced doses containing a pseudo-carrier, 9-hydroxypropyl-(+)-dihydrotetrabenazine (AV-149). To test the possible side effects of this pseudo-carrier, comparative dynamic PET scans of the brains of normal monkeys (2 each) and uni-laterally 6-OH-dopamine-lesioned PD monkeys (2 each) were performed using (18)F-AV-133 doses prepared by either SPE (containing pseudo-carrier) or HPLC (containing no pseudo-carrier). Autoradiographs of post mortem monkey brain sections were evaluated to confirm the relative (18)F-AV-133 uptake in the PD monkey brains and the effects of the pseudo-carrier on VMAT2 binding. The radiochemical purity of the (18)F-AV-133, whether prepared by SPE or by HPLC, was excellent (>99%). PET scans of normal and PD monkey brains showed an expected reduction of VMAT2 in the lesioned areas of the striatum. It was not affected by the presence of the pseudo-carrier, AV-149 (maximally 250 μg/dose). The reduced uptake in the striatum of the lesioned monkey brains was confirmed by autoradiography. Ex vivo inhibition studies of (18)F-AV-133 binding in rat brains, conducted with increasing amounts of AV-149, suggested that at the highest concentration (3.5mg/kg) the VMAT2 binding in the striatum was only moderately blocked (20% reduction). The pseudo-carrier, AV-149, did not affect the (18)F-AV-133/PET imaging of VMAT2 binding sites in normal or uni-laterally lesioned monkey brains. The new streamlined SPE purification method will enable (18)F-AV-133 to be widely available for routine clinical application in

  13. Homogeneous bilateral block shifts

    Indian Academy of Sciences (India)

    A new 3-parameter family of homogeneous 2-by-2 block shifts is described. These are the first examples of irreducible homogeneous bilateral block shifts of block size larger than 1. Author Affiliations. Adam Korányi1. Department of Mathematics, The Graduate Center, City University of New York, New York, NY 10016, USA ...

  14. Trans-channel interactions in batrachotoxin-modified skeletal muscle sodium channels: voltage-dependent block by cytoplasmic amines, and the influence of mu-conotoxin GIIIA derivatives and permeant ions.

    Science.gov (United States)

    Pavlov, Evgeny; Britvina, Tatiana; McArthur, Jeff R; Ma, Quanli; Sierralta, Iván; Zamponi, Gerald W; French, Robert J

    2008-11-01

    External mu-conotoxins and internal amine blockers inhibit each other's block of voltage-gated sodium channels. We explore the basis of this interaction by measuring the shifts in voltage-dependence of channel inhibition by internal amines induced by two mu-conotoxin derivatives with different charge distributions and net charges. Charge changes on the toxin were made at residue 13, which is thought to penetrate most deeply into the channel, making it likely to have the strongest individual interaction with an internal charged ligand. When an R13Q or R13E molecule was bound to the channel, the voltage dependence of diethylammonium (DEA)-block shifted toward more depolarized potentials (23 mV for R13Q, and 16 mV for R13E). An electrostatic model of the repulsion between DEA and the toxin simulated these data, with a distance between residue 13 of the mu-conotoxin and the DEA-binding site of approximately 15 A. Surprisingly, for tetrapropylammonium, the shifts were only 9 mV for R13Q, and 7 mV for R13E. The smaller shifts associated with R13E, the toxin with a smaller net charge, are generally consistent with an electrostatic interaction. However, the smaller shifts observed for tetrapropylammonium than for DEA suggest that other factors must be involved. Two observations indicate that the coupling of permeant ion occupancy of the channel to blocker binding may contribute to the overall amine-toxin interaction: 1), R13Q binding decreases the apparent affinity of sodium for the conducting pore by approximately 4-fold; and 2), increasing external [Na(+)] decreases block by DEA at constant voltage. Thus, even though a number of studies suggest that sodium channels are occupied by no more than one ion most of the time, measurable coupling occurs between permeant ions and toxin or amine blockers. Such interactions likely determine, in part, the strength of trans-channel, amine-conotoxin interactions.

  15. Ground reaction curve based upon block theory

    International Nuclear Information System (INIS)

    Yow, J.L. Jr.; Goodman, R.E.

    1985-09-01

    Discontinuities in a rock mass can intersect an excavation surface to form discrete blocks (keyblocks) which can be unstable. Once a potentially unstable block is identified, the forces affecting it can be calculated to assess its stability. The normal and shear stresses on each block face before displacement are calculated using elastic theory and are modified in a nonlinear way by discontinuity deformations as the keyblock displaces. The stresses are summed into resultant forces to evaluate block stability. Since the resultant forces change with displacement, successive increments of block movement are examined to see whether the block ultimately becomes stable or fails. Two-dimensional (2D) and three-dimensional (3D) analytic models for the stability of simple pyramidal keyblocks were evaluated. Calculated stability is greater for 3D analyses than for 2D analyses. Calculated keyblock stability increases with larger in situ stress magnitudes, larger lateral stress ratios, and larger shear strengths. Discontinuity stiffness controls blocks displacement more strongly than it does stability itself. Large keyblocks are less stable than small ones, and stability increases as blocks become more slender

  16. Micellization of a novel type of hydrophilic/hydrophobic block copolymers

    Czech Academy of Sciences Publication Activity Database

    Tuzar, Zdeněk; Lochmann, Lubomír; Janata, Miroslav; Munk, P.

    2001-01-01

    Roč. 6, č. 5 (2001), s. 437-444 ISSN 1023-666X R&D Projects: GA ČR GA203/95/1240; GA ČR GA203/96/1381; GA AV ČR KSK2050602 Institutional research plan: CEZ:AV0Z4050913 Keywords : hydrophilic/hydrophobic block copolymers * polymeric micelles * static and dynamic light scattering Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.490, year: 2001

  17. Påliteligheten av selvrapportert alkoholkonsum. Svalbardstudien 1988-89

    Directory of Open Access Journals (Sweden)

    Georg Høyer m. fl

    2009-10-01

    Full Text Available  SAMMENDRAGSvalbard er spesielt godt egnet til å vurdere påliteligheten av selvrapportert alkoholkonsum. På grunn av detlave prisnivået for alkohol er ulovlig import eller hjemmeproduksjon av alkohol ukjent på Svalbard. Dessutener samfunnet lite og oversiktlig, slik at det er praktisk mulig å undersøke hele befolkningen. I den aktuellestudien registrerte vi alt salg av alkohol til fastboende nordmenn på Svalbard i oktober og november 1988. Isamme tidsperiode ble alle nordmenn 18 år eller eldre invitert til å ta del i en helseundersøkelse der det inngikkspørsmål om alkoholbruk. Vi fant at selvrapportert alkoholkonsum utgjorde rundt 40% av salgsvolumet.På grunn av de spesielle forhold når det gjelder alkoholomsetning på Svalbard er det grunn til å anta atestimatet i denne studien er mer pålitelig sammenlignet med tilsvarende studier fra andre områder.Høyer G, Nilssen O, Brenn T, Schirmer H. The reliability of self-reported alcohol consumption.The Svalbard study 1988-89. Nor J Epidemiol 1996; 6 (1: 109-113.ENGLISH SUMMARYThe Norwegian island of Spitzbergen, Svalbard offers a unique setting for validation studies on self-reportedalcohol consumption. No counterfeit production or illegal import exists, thus making a complete registrationof all sources of alcohol possible. In this study we recorded sales from all agencies selling alcohol onSvalbard over a two month period in 1988. During the same period all adults living permanently on Svalbardwere invited to take part in a health screening. As part of the screening a self-administered questionnaire onalcohol consumption was introduced to the participants. We found that the self-reported volume accounted forapproximately 40 percent of the sales volume. Because of the unique situation applying to Svalbard, theestimate made in this study is believed to be more reliable compared to other studies using sales volume tovalidate self-reports.

  18. Ionization of amphiphilic acidic block copolymers.

    Science.gov (United States)

    Colombani, Olivier; Lejeune, Elise; Charbonneau, Céline; Chassenieux, Christophe; Nicolai, Taco

    2012-06-28

    The ionization behavior of an amphiphilic diblock copolymer poly(n-butyl acrylate(50%)-stat-acrylic acid(50%))(100)-block-poly(acrylic acid)(100) (P(nBA(50%)-stat-AA(50%))(100)-b-PAA(100), DH50) and of its equivalent triblock copolymer P(nBA(50%)-stat-AA(50%))(100)-b-PAA(200)-b-P(nBA(50%)-stat-AA(50%))(100) (TH50) were studied by potentiometric titration either in pure water or in 0.5 M NaCl. These polymers consist of a hydrophilic acidic block (PAA) connected to a hydrophobic block, P(nBA(50%)-stat-AA(50%))(100), whose hydrophobic character has been mitigated by copolymerization with hydrophilic units. We show that all AA units, even those in the hydrophobic block could be ionized. However, the AA units within the hydrophobic block were less acidic than those in the hydrophilic block, resulting in the preferential ionization of the latter block. The preferential ionization of PAA over that of P(nBA(50%)-stat-AA(50%))(100) was stronger at higher ionic strength. Remarkably, the covalent bonds between the PAA and P(nBA(50%)-stat-AA(50%))(100) blocks in the diblock or the triblock did not affect the ionization of each block, although the self-association of the block copolymers into spherical aggregates modified the environment of the PAA blocks compared to when PAA was molecularly dispersed.

  19. Blocked Randomization with Randomly Selected Block Sizes

    Directory of Open Access Journals (Sweden)

    Jimmy Efird

    2010-12-01

    Full Text Available When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  20. Blocked randomization with randomly selected block sizes.

    Science.gov (United States)

    Efird, Jimmy

    2011-01-01

    When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  1. 31 CFR 595.301 - Blocked account; blocked property.

    Science.gov (United States)

    2010-07-01

    ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM SANCTIONS REGULATIONS General Definitions § 595.301 Blocked account; blocked property. The terms blocked account and blocked...

  2. Validation of a Real-time AVS Encoder on FPGA

    Directory of Open Access Journals (Sweden)

    Qun Fang Yuan

    2014-01-01

    Full Text Available A whole I frame AVS real-time video encoder is designed and implemented on FPGA platform in this paper. The system uses the structure of the flow calculation, coupled with a dual-port RAM memory between/among the various functional modules. Reusable design and pipeline design are used to optimize various encoding module and to ensure the efficient operation of the pipeline. Through the simulation of ISE software and the verification of Xilinx Vritex-4 pro platform, it can be seen that the highest working frequency can be up to 110 MHz, meeting the requirements of the whole I frame real- time encoding of AVS in CIF resolution.

  3. Wirevagn : Utvecklingen av en utrullare för hisslinor

    OpenAIRE

    Rehnsfeldt, Patrik

    2014-01-01

    Kandidatexamensarbetet som utgick från en förfrågan från företaget Irongrip AB hade som mål att utveckla ett produktförslag på en utlindare av stålvajer för hissmontörer. Irongrip AB som tillverkar och säljer verktyg för hantering av stålvajer hade uppmärksammat att en efterfrågan på en sådan produkt fanns på marknaden då befintliga lösningar var bristfälliga och inte hade alla de funktioner som är önskvärda hos en sådan produkt.Arbetet inleddes med en förstudie där studiebesök vid lindragnin...

  4. EST Table: AV402406 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV402406 heS00974 10/09/28 59 %/223 aa ref|XP_001656104.1| dipeptidyl peptidase iii...174102|DmojGI24885-PA 10/08/27 40 %/219 aa F02E9.9b#CE41217#WBGene00008532#status...ref|XP_972969.2| PREDICTED: similar to dipeptidyl peptidase iii [Tribolium castaneum] FS761400 heS0 ...

  5. Beregning av lokk, håndberegningsmetoder versus FEM

    OpenAIRE

    Bruder, Ørjan Myklestad

    2014-01-01

    Ved dimensjonering av lokk benyttes vanligvis elementmetoden (FEM) til å fastlegge spenning og deformasjon i konstruksjonen. Det finnes flere håndberegningsmetoder for å verifisere FEM-resultatene, men det er lite tilgjengelig litteratur om temaet, og lite er gjort for å sammenligne metodene. IMT ved NMBU ønsker å styrke fagkunnskapen innenfor dette temaet og har derfor initiert denne mastergradsoppgaven. Målsettingen med denne oppgaven har vært å sammenligne ulike håndberegningsformler for ...

  6. EST Table: AV403457 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403457 msgV0503 10/09/28 90 %/177 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  7. EST Table: AV403247 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403247 msgV0234 10/09/28 91 %/189 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  8. EST Table: AV403467 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403467 msgV0519 10/09/28 85 %/159 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  9. EST Table: AV403356 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403356 msgV0366 10/09/28 66 %/121 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB985569 msgV ...

  10. EST Table: AV403304 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403304 msgV0310 10/09/28 85 %/165 aa ref|NP_001166287.1| sericin 2 isoform 1 prec...ursor [Bombyx mori] gb|ADA84147.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  11. EST Table: AV403504 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403504 msgV0623 10/09/28 98 %/114 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  12. EST Table: AV403487 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403487 msgV0602 10/09/28 95 %/130 aa ref|NP_001166287.1| sericin 2 isoform 1 prec...ursor [Bombyx mori] gb|ADA84147.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  13. EST Table: AV403164 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403164 msgV0119 10/09/28 84 %/120 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  14. EST Table: AV403698 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403698 msgV0982 10/09/28 85 %/164 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  15. EST Table: AV403268 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403268 msgV0258 10/09/28 62 %/158 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  16. EST Table: AV403374 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403374 msgV0392 10/09/28 86 %/135 aa ref|NP_001166287.1| sericin 2 isoform 1 prec...ursor [Bombyx mori] gb|ADA84147.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  17. EST Table: AV403444 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403444 msgV0485 10/09/28 80 %/156 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  18. EST Table: AV403508 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403508 msgV0629 10/09/28 79 %/122 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h NM_001172817 msgV ...

  19. EST Table: AV403123 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403123 msgV0067 10/09/28 65 %/125 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB985569 msgV ...

  20. EST Table: AV403443 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403443 msgV0483 10/09/28 62 %/162 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB985569 msgV ...

  1. EST Table: AV403596 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403596 msgV0735 10/09/28 60 %/200 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB985569 msgV ...

  2. EST Table: AV403709 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV403709 msgV0994 10/09/28 61 %/173 aa ref|NP_001166288.1| sericin 2 isoform 2 prec...ursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB985569 msgV ...

  3. Bruk av studenter som medforskere- et pilotprosjekt i barnevernsfeltet

    Directory of Open Access Journals (Sweden)

    Kjersti Ørvig

    2014-02-01

    Full Text Available Denne artikkelen retter fokus mot studenters læring i praksis. Gjennom beskrivelsen av et pilotprosjekt i barnevernet, ønsker vi å synliggjøre hvordan bruken av studenter som medforskere kan bidra til økt kunnskapsutbytte samt en større forståelse av samspillet mellom teori og praksis. Samtidig har feltet sosialt arbeid behov for en modernisering. Denne artikkelen søker å vise at bruk av studenter som medforskere kan bidra til den nevnte modernisering. To spørsmål reises i artikkelen: Hvordan håndterer lærere og studenter utfordringer i forskningsprosessen i prosjekter hvor studenter deltar som medforskere? På hvilken måte kan praksisnær forskning bidra til å kaste lys over studentens læring? Abstract Students as research assistants – a pilot project in child welfare services.This article concerns students’ learning outcomes. Through a description of a pilot project in child welfare services, the aim is to demonstrate how the use of students as research assistants can contribute to increased knowledge outcomes and provide a better understanding of the interaction between theory and practice. At the same time, the field of social work needs a modernization. The article argues that the use of students as research assistants can contribute to the aforementioned modernization. Two issues are raised in the article: How to deal with teachers’ and students’ challenges in the research process in projects where students participate as research assistants? In what way can survivor research shed light on students’ learning outcomes?

  4. Inkludering av ungdom med minoritetsbakgrunn i NIF-organisert idrett

    Directory of Open Access Journals (Sweden)

    Mari Kristin Sisjord

    2014-10-01

    Full Text Available Norges Idrettsforbund og Olympiske og Paralympiske Komité (NIF har en uttalt målsetting om en åpen og inkluderende idrett. Hvordan kommer dette til uttrykk i den praktiske virksomheten? Denne artikkelen, som bygger på data fra en undersøkelse om likestilling og mangfold i den organiserte idretten (NIF, retter søkelyset mot arbeid med inklusjon av ungdom med minoritetsbakgrunn på ulike organisasjonsnivå i NIF: særforbund, idrettskretser og idrettslag. Datamaterialet er kvalitative intervju med representanter fra ulike organisasjonsnivå. Resultatene viser at NIFs overordnede politikk i varierende grad nedfelles i særforbundenes virksomhet, i idrettskretsene og i idrettslagene. Av særforbundene skiller Fotballforbundet og Klatreforbundet seg ut som aktive pådrivere i arbeidet med inkludering. Mange idrettslag oppfattet slike spørsmål som lite aktuelle i sitt rekrutteringsområde. Representanter for lag som hadde erfaring med inkludering og rekruttering av minoritetsungdom, tilkjennega varierte erfaringer og synspunkter.

  5. Torsional changes in surgery for A-V phenomena.

    Science.gov (United States)

    Sharma, P; Halder, M; Prakash, P

    1997-03-01

    The role of torsion in the aetiopathogenesis of A-V phenomena has not been sufficiently emphasized. The success of vertical displacement of horizontal recti in correction of A or V has not been attributed to torsional changes. To evaluate this aspect, 21 cases of A or V phenomena were subjected to monocular recession-resection procedure with vertical shifting. Preoperative and postoperative torsional changes were evaluated on synoptophore (subjective torsion), and confirmed by fundus photography (objective torsion). Intorsion with A phenomenon was seen preoperatively in 5 of 8 cases which increased after surgery and was seen postoperatively in the other 3 cases also. Extorsion was observed in 5 of 13 cases pre operatively in 'V' phenomenon, but the changes in extorsion after surgery were less dramatic than those in intorsion. The oblique overactions were reduced in cases where they were present. Correction of A-V phenomena by torsion induced by vertical shifting of horizontal recti muscles is proposed, highlighting the role of torsion in A-V phenomena.

  6. Torsional changes in surgery for A-V phenomena

    Directory of Open Access Journals (Sweden)

    Sharma Pradeep

    1997-01-01

    Full Text Available The role of torsion in the aetiopathogenesis of A-V phenomena has not been sufficiently emphasized. The success of vertical displacement of horizontal recti in correction of A or V has not been attributed to torsional changes. To evaluate this aspect, 21 cases of A or V phenomena were subjected to monocular recession-resection procedure with vertical shifting. Preoperative and postoperative torsional changes were evaluated on synoptophore (subjective torsion, and confirmed by fundus photography (objective torsion. Intorsion with A phenomenon was seen preoperatively in 5 of 8 cases which increased after surgery and was seen postoperatively in the other 3 cases also. Extorsion was observed in 5 of 13 cases pre operatively in ′V′ phenomenon, but the changes in extorsion after surgery were less dramatic than those in intorsion. The oblique overactions were reduced in cases where they were present. Correction of A-V phenomena by torsion induced by vertical shifting of horizontal recti muscles is proposed, highlighting the role of torsion in A-V phenomena.

  7. Modified cyanobacteria

    Science.gov (United States)

    Vermaas, Willem F J.

    2014-06-17

    Disclosed is a modified photoautotrophic bacterium comprising genes of interest that are modified in terms of their expression and/or coding region sequence, wherein modification of the genes of interest increases production of a desired product in the bacterium relative to the amount of the desired product production in a photoautotrophic bacterium that is not modified with respect to the genes of interest.

  8. Generalized Block Failure

    DEFF Research Database (Denmark)

    Jönsson, Jeppe

    2015-01-01

    Block tearing is considered in several codes as a pure block tension or a pure block shear failure mechanism. However in many situations the load acts eccentrically and involves the transfer of a substantial moment in combination with the shear force and perhaps a normal force. A literature study...... shows that no readily available tests with a well-defined substantial eccentricity have been performed. This paper presents theoretical and experimental work leading towards generalized block failure capacity methods. Simple combination of normal force, shear force and moment stress distributions along...

  9. Har forhold under svangerskapet betydning for utviklingen av otitis media?

    Directory of Open Access Journals (Sweden)

    Kari J. Kværner

    2009-10-01

    Full Text Available  SAMMENDRAGMed utgangspunkt i data fra et populasjonsbasert utvalg av 7 992 norske tvillinger ble sammenhengenmellom gjentatte ørebetennelser og forhold under svangerskapet studert. Som parametre på intrauterinevekstforhold ble informasjon om fødselsvekt og gestasjonsalder fra Medisinsk Fødselsregister benyttet.Informasjon om rapporterte øreinfeksjoner ble basert på spørreskjemaer som ble besvart av tvillingene ialderen 18–25 år. Først studerte vi individuelle effekter av fødselsvekt og gestasjonsalder på forekomsten avotitis media (OM. Rapportert fødselsvekt hos individer med OM var signifikant lavere enn hos kontrollene,med en gjennomsnittsforskjell på 86 gram. Hos de som rapporterte OM var gjennomsnittlig gestasjonsalder3 dager kortere enn i kontrollmaterialet. Deretter beregnet vi effekten av fødselsvekt ved bruk av co-twinkontroll metoden. Blant monozygote (MZ tvillingpar gjenspeiler fødselsvektforskjeller innenfor tvillingparetintra-uterine miljøforskjeller. Blant dizygote (DZ par kan vektforskjellen være både genetiske ogmiljøbetinget. Ved sammenligning av fødselsvektforskjeller innenfor tvillingparene er tvillingen som ikkehar gjentatte øreinfeksjoner en matchet kontroll blant OM diskordante par. Resultatene antyder at lavfødselsvekt er en risikofaktor for otitis media. Gjennomsnittlig vektforskjell blant par diskordante for OMvar 48 gram, og den av tvillingen som ikke rapporterte OM hadde signifikant høyere fødselsvekt.Kværner KJ, Tambs K, Harris J, Magnus P. Do pregnancy-related factors influence the development ofotitis media? Nor J Epidemiol 1997; 7 (1: 55-58.  ENGLISH SUMMARYThe association between intrauterine growth, as measured by weight and gestational age, and the occurrenceof recurrent ear infections was studied using data from a population based sample of 7992 Norwegian twins.Perinatal measures were collected from the Medical Birth Registry, and reports of recurrent ear infectionswere based on

  10. Congenital and childhood atrioventricular blocks: pathophysiology and contemporary management.

    Science.gov (United States)

    Baruteau, Alban-Elouen; Pass, Robert H; Thambo, Jean-Benoit; Behaghel, Albin; Le Pennec, Solène; Perdreau, Elodie; Combes, Nicolas; Liberman, Leonardo; McLeod, Christopher J

    2016-09-01

    Atrioventricular block is classified as congenital if diagnosed in utero, at birth, or within the first month of life. The pathophysiological process is believed to be due to immune-mediated injury of the conduction system, which occurs as a result of transplacental passage of maternal anti-SSA/Ro-SSB/La antibodies. Childhood atrioventricular block is therefore diagnosed between the first month and the 18th year of life. Genetic variants in multiple genes have been described to date in the pathogenesis of inherited progressive cardiac conduction disorders. Indications and techniques of cardiac pacing have also evolved to allow safe permanent cardiac pacing in almost all patients, including those with structural heart abnormalities. Early diagnosis and appropriate management are critical in many cases in order to prevent sudden death, and this review critically assesses our current understanding of the pathogenetic mechanisms, clinical course, and optimal management of congenital and childhood AV block. • Prevalence of congenital heart block of 1 per 15,000 to 20,000 live births. AV block is defined as congenital if diagnosed in utero, at birth, or within the first month of life, whereas childhood AV block is diagnosed between the first month and the 18th year of life. As a result of several different etiologies, congenital and childhood atrioventricular block may occur in an entirely structurally normal heart or in association with concomitant congenital heart disease. Cardiac pacing is indicated in symptomatic patients and has several prophylactic indications in asymptomatic patients to prevent sudden death. • Autoimmune, congenital AV block is associated with a high neonatal mortality rate and development of dilated cardiomyopathy in 5 to 30 % cases. What is New: • Several genes including SCN5A have been implicated in autosomal dominant forms of familial progressive cardiac conduction disorders. • Leadless pacemaker technology and gene therapy for

  11. Tristrams saga ok Isöndar og Tristan und Isold - En lesning av to versjoner av Tristan-legenden

    OpenAIRE

    Jensen, Kristian Arnstein

    2015-01-01

    Abstrakt (norsk) / Abstract (Norwegian) Oppgaven omhandler den norrøne og middelaldertyske versjonen av legenden om Tristan og Isolde. Kjærlighetsmotivet sammenliknes og fortellingen sammenliknes med et eventyr. Vladimir Propps og A. J. Greimas teorier om litteraturteori i forhold til fortellingen taes i bruk. Abstract (engelsk) / Abstract (English) The assignment is about the old norse and medieval german version of the legend of Tristan and Isolde. The love motive is compa...

  12. Å LESE MEDIETEKSTER PÅ IPADEN. Observasjoner av en medievant fireårings bruk av iPad i hjemmet

    Directory of Open Access Journals (Sweden)

    Henriette Jæger

    2016-06-01

    Full Text Available Artikkelen tar utgangspunkt i tre observasjoner av en gutt på fire år som bruker iPad på fritiden. Den søker å synliggjøre de strategiene dette barnet velger for å skaffe seg tilgang til ulike medietekster, hvordan han leser og tolker dem, og den undersøker eventuelle spor av kritisk refleksjon hos barnet over disse tekstene. Teoretisk sett hviler den på en forståelse av mediekompetanse som en parallell prosess til utvikling av lese- og skrivekyndighet (literacy, og medieopplevelsene omtales som viktige møter med tekst. Artikkelen undersøker hvordan å lese medietekster kan legge et grunnlag for å utvikle en utvidet tekstkompetanse eller mediekompetanse. Konklusjonen legger vekt på motivasjon og lekenhet som barns primære inngang til medietekstene og som et grunnlag for å utvikle mediekompetanse (media literacy. The article is based on three observations of a four-year-old boy who uses the iPad in his spare time. It demonstrates the strategies that this boy applies to gain access to various media texts, and how he reads and interprets them. It also seeks to examine traces of critical reflection that he may demonstrate in relation to these texts. Theoretically, it rests on an understanding of media literacy as a parallel process to the development of literacy, and it seeks to demonstrate how reading media texts can create an important starting point for the development of media literacy. The Kindergarten practitioner’s role and opportunities to develop children's media literacy within a kindergarten context is a focus towards the end of the article. In conclusion, I argue that motivation and playfulness are important approaches to media texts and create an important foundation for the development of media literacy

  13. Hvilken rolle spiller hybrid shopping i kundereisen ved kjøp av kosmetikk?

    OpenAIRE

    Varem, Andrea; Nervik, Lene

    2017-01-01

    Temaet for denne bacheloroppgaven er hybrid shopping i kundereisen ved kjøp av kosmetikk. Etter en omfattende gjennomgang av eksisterende teori rundt kundereisen fikk vi et inntrykk av at det er et gap i forskningen knyttet til kundereisen ved kjøp av kosmetikk, på tross av størrelsen på dette markedet. Det vi fant av teori på feltet var i stor grad basert på kvantitative undersøkelser, og vi ønsker derfor å belyse kundereisen i denne konteksten gjennom et kvalitativt forskningsdesign. Med ut...

  14. Direct voltammetric analysis of DNA modified with enzymatically incorporated 7-deazapurines

    Czech Academy of Sciences Publication Activity Database

    Pivoňková, Hana; Horáková Brázdilová, Petra; Fojtová, Miloslava; Fojta, Miroslav

    2010-01-01

    Roč. 82, č. 16 (2010), s. 6807-6813 ISSN 0003-2700 R&D Projects: GA AV ČR(CZ) IAA400040901; GA MŠk(CZ) LC06035 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : modified DNA * 7-deazapurines * voltammetric analysis Subject RIV: BO - Biophysics Impact factor: 5.874, year: 2010

  15. Homogeneous bilateral block shifts

    Indian Academy of Sciences (India)

    Homogeneous bilateral block shifts. ADAM KORÁNYI. Department of Mathematics, The Graduate Center, City University of New York,. New York, NY 10016, USA. E-mail: Adam.Koranyi@lehman.cuny.edu. MS received 18 January 2013. Abstract. A new 3-parameter family of homogeneous 2-by-2 block shifts is described.

  16. Related Drupal Nodes Block

    NARCIS (Netherlands)

    Van der Vegt, Wim

    2010-01-01

    Related Drupal Nodes Block This module exposes a block that uses Latent Semantic Analysis (Lsa) internally to suggest three nodes that are relevant to the node a user is viewing. This module performs three tasks. 1) It periodically indexes a Drupal site and generates a Lsa Term Document Matrix.

  17. Control rod blocking monitor

    International Nuclear Information System (INIS)

    Suzuki, Shigeru.

    1993-01-01

    The number of times for setting up a control rod blocking monitor of a BWR type power plant is remarkably reduced to mitigate operator's burden. In the control rod blocking monitor, trip levels, as a judging standard upon outputting control rod blocking inhibition signals, are set up stepwise depending on the power level around control rods put to blocking control. The present invention comprises an allowance judging means capable of setting up trip levels for each of power levels corresponding to a plurality of control rods at once if the power levels are within the set up allowable range. With such a constitution, the set up allowable range is determined previously in the allowance judging means. Accordingly, when a gang blocking is conducted to control rods, if power levels around the control rods are increased at once into the set up allowable range, the trip levels for each of the control rods are set up at once. (I.S.)

  18. Rettferdige minutter: Fordeling av spilletid i fotballkamper for aldersbestemte klasser

    Directory of Open Access Journals (Sweden)

    Trine Anker

    2010-01-01

    Full Text Available På et fotballag i overgangen mellom barne- og ungdomsfotballen er spilletid på fotballbanen under kamp både en knapp ressurs og en kilde til diskusjoner om fordeling. Spørsmålet som er utgangspunkt for denne artikkelen, er hvilke hensyn som bør tas når trener og lagleder skal fordele samlet spilletid på enkeltspillere. Er det viktigst å vinne fotballkampen, eller har det størst betydning å fordele spilletiden mest mulig likt mellom spillerne? Skal det tas hensyn til guttenes evner, motivasjon og preferanser? Er deres familiebakgrunn og personlighet av betydning? Diskusjonen baserer seg på en gjennomgang av ulike politiske rettferdighetsteorier for fordeling av knappe goder.Nøkkelord: rettferdighet, practice, fordelingsrettferdighet, diskursetikk, idrettsetikkEnglish summary: Minutes of justice: Distribution of time during football matches in a boys' teamDuring a football match, time for playing can be considered as a limited good. In this article the point of departure is the redistribution of time in a boys' football team in the transition phase between children and youth football. The questions are how and under which conditions time for playing should be distributed among the players. Is winning the game more important than trying to let every player play for an equal amount of time? Should the boys' talents, motivation, and preferences be considered while distributing time, or are family background and personality of importance? Different theories of political justice for the distribution of limited goods underpin the discussion of how to distribute the minutes of playing time during a football match.http://dx.doi.org/10.5324/eip.v4i1.1737

  19. Implementering av HMS-system ved Frank Mohn Fusa AS

    OpenAIRE

    Jørgensen, Hilde

    2008-01-01

    Det stilles stadig strengere HMS- og kvalitetskrav til virksomheter. Frank Mohn Fusa AS må overholde krav fra myndigheter, interne krav, kundekrav og krav i henhold til bedriftens ISO 9001:2000 sertifisering. Bedriften hadde et HMS- og kvalitetssystem, som ved hjelp av en operasjonsmanual og en kvalitetshåndbok dokumenterte de fleste krav, men bedriften behøvde et mer effektivt, kostnadsbesparende og moderne system! Det ble utført Compliance-målinger opp mot ISO 9001:2000 og In...

  20. Posthumanisme /nymaterialisme og nomadisme - affektive brytninger av barnehagens observasjonspraksiser

    Directory of Open Access Journals (Sweden)

    Ann Merete Otterstad

    2015-09-01

    Full Text Available This article challenges observation as a method in early childhood, justified as a mapping tool for creating knowledge about children. Observation as data material is about writing down already known categorisation about children and their development. Categories and categorisation make a foundation for correspondence and coherence   - connections that might create generalising knowledge about children in early years. The article is about a research project conducted in a child-centre over a two-year period. We had an on-going conversation with the personnel around theories about ‘child development’. In the article we experiment with observation based on posthuman/newmaterial theories. Our specific interests are to explore the complexities around observation by asking; why observations, what do we expect through observation, and what might observation as datamaterial be/become? We are inspired by the Norwegian film “Kitchen Stories” (Salmer fra Kjøkkenet, Hamer, 2003 both as affect/provocation and desire (Koro-Ljungberg & MacLure, 2013. We search for affective bending and messiness (Lather, 2007; Law, 2004 to disturb and challenge observation as dominating paradigm in the field of early years, to break some patterns around the positioning of data material. Artikkelen utfordrer observasjon i barnehagen ut fra at metoden brukes som verktøy for å kartlegge og danne grunnlaget for utvikling av kunnskap om barn.  Observasjon som datamateriale innebærer iakttagelser og nedtegnelser av allerede gitte kategoriseringer om barn og barns utvikling.  Kategorier og kategorisering legger grunnlag for mønster som har i seg ideer om korrespondanse og koherens – sammenhenger som kan bidra til generaliserende kunnskap om barna i barnehagen. Omrisset av artikkelen dreies rundt et forskningsarbeid gjort i en barnehage over en toårs-periode, der vi sammen med de ansatte diskuterer teorier om barn og barns ’utvikling’. Vi bruker posthumane

  1. EST Table: AV404130 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available n (Reed-Steinberg cell-expressed intermediate filament-associated protein) [Tribolium castaneum] 10/08/28 53...78 aa gnl|Amel|GB30360-PB 10/09/10 54 %/199 aa gi|189241063|ref|XP_967018.2| PREDICTED: similar to restin (Reed-Steinberg cell-expres...sed intermediate filament-associated protein) [Tribolium castaneum] FS906662 pg-- ... ...AV404130 pg--0509 10/09/28 54 %/199 aa ref|XP_967018.2| PREDICTED: similar to resti

  2. Tillämpning av IAS 40 i onoterade fastighetsbolag

    OpenAIRE

    Wallin, Fredrik; Nilsson, Karolina; Ericsson, Marina

    2006-01-01

    Enligt IAS 40 – Förvaltningsfastigheter, definieras förvaltningsfastigheter som ”mark eller byggnader eller del av byggnad som innehas i syfte att generera hyresinkomster eller värdestegring”. Onoterade fastighetsbolag i Sverige har idag möjlighet att välja mellan att värdera sina fastigheter till anskaffningsvärde eller verkligt värde. IAS – International Accounting Standards är en internationell redovisningsstandard inom EU som började tillämpas i januari 2001, men blev obligatorisk för bör...

  3. Uranienborg skole : forbedring av skolens uterom i den tette byen

    OpenAIRE

    Thorstensen, Helene

    2011-01-01

    Denne oppgaven fokuserer på skolegårdsforbedring i indre by, og tar for seg Uranienborg skole som et eksempel. Gjennom oppgaven er det jobbet fra et overordnet nivå og ned til et utformingsforslag på et mer detaljert nivå. Det er lagt vekt på hvordan man best mulig kan tilrettelegge når utearealet skolen har rådighet over er begrenset, noe som i dag er en svært aktuell problemstilling i tette byer. Oppgaven består av fire deler: registrering og analyse, teori, referanseprosj...

  4. Dyes adsorption on magnetically modified Chlorella vulgaris cells

    Czech Academy of Sciences Publication Activity Database

    Šafaříková, Miroslava; Pona, B. M. R.; Mosiniewicz-Szablewska, E.; Weyda, František; Šafařík, Ivo

    2008-01-01

    Roč. 17, č. 4 (2008), s. 486-492 ISSN 1018-4619 R&D Projects: GA MŠk OC 108; GA MPO 2A-1TP1/094 Institutional research plan: CEZ:AV0Z60870520; CEZ:AV0Z50070508 Keywords : Chlorella vulgaris * magnetically modified cells * dyes Subject RIV: EI - Biotechnology ; Bionics Impact factor: 0.463, year: 2008

  5. Synthesis of oligoribonucleotides with phosphonate-modified linkages

    Czech Academy of Sciences Publication Activity Database

    Páv, Ondřej; Kóšiová, Ivana; Barvík, I.; Pohl, Radek; Buděšínský, Miloš; Rosenberg, Ivan

    2011-01-01

    Roč. 9, č. 17 (2011), s. 6120-6126 ISSN 1477-0520 R&D Projects: GA ČR GA202/09/0193; GA AV ČR KAN200520801; GA MŠk(CZ) LC06061 Institutional research plan: CEZ:AV0Z40550506 Keywords : oligoribonucleotide * phosphonate * modified RNA Subject RIV: CC - Organic Chemistry Impact factor: 3.696, year: 2011

  6. Block floating point for radar data

    DEFF Research Database (Denmark)

    Christensen, Erik Lintz

    1999-01-01

    Integer, floating point, and block floating point (BFP) data formats are analyzed and compared in order to establish the mathematical tools for selection of an optimal format which fulfils the demands of high resolution radar (SAR) data to large dynamic range and adequate S/N. The analysis takes...... quantization noise and saturation distortion into account and concludes that it is preferred to use small blocks and a (new) modified BFP format applying fractional exponents. Data from the EMISAR radar system are applied to illustrate the merits of the different schemes....

  7. IceBridge LVIS POS/AV L1B Corrected Position and Attitude Data

    Data.gov (United States)

    National Aeronautics and Space Administration — The IceBridge LVIS POS/AV L1B Corrected Position and Attitude Data (IPPLV1B) data set contains georeferencing data from the Applanix 510 and 610 POS AV systems flown...

  8. IceBridge POS/AV L1B Corrected Position and Attitude Data

    Data.gov (United States)

    National Aeronautics and Space Administration — The IceBridge POS/AV L1B Corrected Position and Attitude (IPAPP1B) data set contains georeferencing data from the Applanix 510 POS AV system flown with the Digital...

  9. Predictability of blocking

    International Nuclear Information System (INIS)

    Tosi, E.; Ruti, P.; Tibaldi, S.; D'Andrea, F.

    1994-01-01

    Tibaldi and Molteni (1990, hereafter referred to as TM) had previously investigated operational blocking predictability by the ECMWF model and the possible relationships between model systematic error and blocking in the winter season of the Northern Hemisphere, using seven years of ECMWF operational archives of analyses and day 1 to 10 forecasts. They showed that fewer blocking episodes than in the real atmosphere were generally simulated by the model, and that this deficiency increased with increasing forecast time. As a consequence of this, a major contribution to the systematic error in the winter season was shown to derive from the inability of the model to properly forecast blocking. In this study, the analysis performed in TM for the first seven winter seasons of the ECMWF operational model is extended to the subsequent five winters, during which model development, reflecting both resolution increases and parametrisation modifications, continued unabated. In addition the objective blocking index developed by TM has been applied to the observed data to study the natural low frequency variability of blocking. The ability to simulate blocking of some climate models has also been tested

  10. UNIPASS for AvSP? A Broader View

    Science.gov (United States)

    Wu, N. Eva

    2001-01-01

    UNIPASS is a general-purpose probabilistic computer program consisting of three major modules, including preprocessor, solver and postprocessor. UNIPASS contains a user-friendly Graphical User Interface (GUI), numerous state-of-the-art probabilistic analysis techniques, a large library of statistical distributions and a function module with a large library of support functions that can easily define any complex limit-state function in a scripting FORTRAN-like syntax format. Its inverse probability analysis and sensitivities analysis capabilities make it a powerful design aid in any product cycle. Its precise numerical analysis engine is accurate enough to push the failure probabilities of a design to well below 10 (exp -50). UNIPASS is equipped with advanced artificial intelligence that is designed to handle systems with an essentially unlimited number of random variables with ease and efficiency. Its modular arrangement allows you to tailor an analysis to the desired level of accuracy and efficiency. The depth and comprehensiveness of UNIPASS are built upon the decades of experience and expertise of industry leaders including Boeing Aircraft, NASA and the DoD. Its rich content also makes UNIPASS a valuable instructional tool for random processes and probabilistic mechanics. The topics include: 1) Reliability in AvSP; 2) Role of UNIPASS in AvSP; and 3) Examples. This paper is in viewgraph form.

  11. Heterogeneous blends of recycled poly(ethylene terephthalate) with impact modifiers: Phase structure and tensile creep

    Czech Academy of Sciences Publication Activity Database

    Pegoretti, A.; Kolařík, Jan; Gottardi, G.; Penati, A.

    2004-01-01

    Roč. 53, č. 7 (2004), s. 984-994 ISSN 0959-8103 R&D Projects: GA AV ČR IAA4050105 Institutional research plan: CEZ:AV0Z4050913 Keywords : polymer blends * poly(ethylene terephthalate) * impact modifiers Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.125, year: 2004

  12. Pyrenebutanoate as a dynamic protein modifier for fluorometric detection in capillary zone electrophoresis

    Czech Academy of Sciences Publication Activity Database

    Horká, Marie; Šlais, Karel

    2002-01-01

    Roč. 23, 7-8 (2002), s. 1090-1095 ISSN 0173-0835 R&D Projects: GA AV ČR IAA4031901 Institutional research plan: CEZ:AV0Z4031919 Keywords : pyrenebutanoate * dynamic protein modifier * CZE Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.325, year: 2002

  13. Ungdommers opplevelser med overdreven bruk av online-rollespillet World of Warcraft

    DEFF Research Database (Denmark)

    Flaaten, Øivind; Torp, Steffen; Aarseth, Espen

    2010-01-01

    Ungdommers bruk av online-rollespill blir ofte problematisert (Falkner 2007). På bakgrunn av kvalitative intervjuer med ti ungdommer og fem pårørendekontakter beskrives i denne artikkelen ungdommenes opplevelser av online-spillet World of Warcraft (WoW). Denne pilotstudien gir en nyansert...... for konflikt og hjelpeløshet. Helsefremmende arbeid basert på dialog og tidlig intervensjon kan forhindre at online-spilladferd kommer ut av kontroll....

  14. Open Source AV solution supporting In Situ Simulation and Clinical education

    DEFF Research Database (Denmark)

    Simonsen, Eivind Ortind; Pociunas, Gintas; Dahl, Mads Ronald

    2015-01-01

    for a portable AV system for VAD. The system would make use of components widely available and easily replaceable. The developed AV software and coding is contracted to be available as Copyleft Open Source to ensure low cost and a potential continues improvement and expansion of the AV system. Summary of results...... debriefing in a mobile, in situ simulation environment using an AV system constructed from “off the shelf” components and Open Source software....

  15. Förebyggande och rehabilitering av Osgood- Schlatter och Sinding-Larsen−Johanssons syndrom : Utformande av en handbok

    OpenAIRE

    Karenko, Sofia

    2016-01-01

    Detta arbete är ett praktiskt inriktat examensarbete där slutprodukten är en handbok med ett förebyggande och rehabiliterande träningsprogram för Osgood-Schlatter och Sinding-Larsen–Johanssons syndrom (SLJ). Syftet med arbetet är att öka kunskapen om syndromen och utforma ett träningsprogram som kan användas vid förebyggande och rehabiliteringen av dessa. Arbetet bygger på Vilkka och Airaksinens modell för praktiskt inriktat examensarbete som beskrivs i boken Toiminnallinen opinn...

  16. Selvbestemmelse og oppdragelse : en teoretisk analyse av oppdragelsens påvirkning på utviklingen av selvbestemmelse

    OpenAIRE

    Hagen, Marit Svennevig; Haugstvedt, Merete Lehne Rugdal

    2007-01-01

    1) Problemstilling Hensikten med oppgaven er å rette fokus mot oppdragelse som en påvirkningsfaktor på utviklingen av selvbestemmelsen, og hvilken betydning behovstilfredsstillelse har for individets subjektive velvære. Oppdragelse er et populært tema som stadig blir debattert i mediene. Det diskuteres blant annet hvorfor oppdragelse er viktig, hvordan det er mulig å oppdra barn på best mulig måte og hvem som er viktige oppdragere i dagens samfunn. Vår oppgave handler om individets selvbes...

  17. 31 CFR 594.301 - Blocked account; blocked property.

    Science.gov (United States)

    2010-07-01

    ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.301 Blocked account; blocked property. The terms blocked account and...

  18. Bundle Branch Block

    Science.gov (United States)

    ... 2015. Bundle branch block Symptoms & causes Diagnosis & treatment Advertisement Mayo Clinic does not endorse companies or products. ... a Job Site Map About This Site Twitter Facebook Google YouTube Pinterest Mayo Clinic is a not- ...

  19. Blocked Urethral Valves

    Science.gov (United States)

    ... the penis. Rarely, small membranes form across the urethra in boys early in pregnancy, and they can block the flow of urine out of the bladder. These membranes are called posterior urethral valves and can have life-threatening consequences ...

  20. Optoelectronics using block copolymers.

    Energy Technology Data Exchange (ETDEWEB)

    Botiz, I.; Darling, S. B.; Center for Nanoscale Materials

    2010-05-01

    Block copolymers, either as semiconductors themselves or as structure directors, are emerging as a promising class of materials for understanding and controlling processes associated with both photovoltaic energy conversion and light emitting devices.

  1. Dimensioning of multiservice links taking account of soft blocking

    DEFF Research Database (Denmark)

    Iversen, Villy Bæk; Stepanov, S.N.; Kostrov, A.V.

    2006-01-01

    In CDMA systems the blocking probability depends on both the state of the system and the bandwidth of the request. Due to soft blocking caused by interference from users in same cell and neighboring cells we have to modify the classical teletraffic theory. In this paper we consider a model...... of a multiservice link taking into account the possibility of soft blocking. An approximate algorithm for estimation of main performance measures is constructed. The error of estimation is numerically studied for different types of soft blocking. The optimal procedure of dimensioning is suggested....

  2. No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic-AV block

    DEFF Research Database (Denmark)

    Thomsen, Morten Bækgaard; Beekman, J D M; Attevelt, N J M

    2006-01-01

    The therapeutically available quinolone antibiotic moxifloxacin has been used as a positive control for prolonging the QT interval in both clinical and non-clinical studies designed to assess the potential of new drugs to delay cardiac repolarization. Despite moxifloxacin prolonging QT, it has...... not been shown to cause torsades de pointes arrhythmias (TdP). Azithromycin is a macrolide antibiotic that has rarely been associated, clinically, with cases of proarrhythmia. As there is a lack of clinical data available, the cardiac safety of these drugs was assessed in a TdP-susceptible animal model...

  3. Hypotension and AV block after diesel exhaust exposure in heart failure-prone rats: role of gaseous and particulate components

    Science.gov (United States)

    Acute inhalations ofdiesel engine exhaust (DE) and fine particulate matter (PM2.5) have been demonstrated to provoke adverse cardiac events in humans with preexisting heart disease. Electrophysiologic dysfunction and autonomic imbalance are among the mechanisms widely held to und...

  4. High-Rate Pacing Reduces Variability of Repolarization and Prevents Repolarization-Dependent Arrhythmias in Dogs With Chronic AV Block

    DEFF Research Database (Denmark)

    Oosterhoff, Peter; Thomsen, Morten Bækgaard; Maas, Joep N

    2010-01-01

    -term variability of repolarization (STV) as a feedback parameter of arrhythmic risk. Methods and Results: The minimal signal sampling frequency required for measuring STV was determined through computer simulation. Arrhythmogenic response to dofetilide (25 µg/kg/5minutes) was tested at two different paced heart...

  5. Anvendelser av EPS i vegbygging - med fokus på brofundamentering og myrbro

    OpenAIRE

    Hermansen, Simen

    2012-01-01

    Oppgaven er delt i to deler. Del A Del A gir en innføring i produksjonen av materialet, materialegenskaper, retningslinjer for bruk av materialet og bruksområder. Norge var først ute i verden med bruk av EPS i vegfyllinger i 1972, siden det har teknikken spredd seg verden over. EPS er den letteste av de lette massene som brukes i vegfyllinger med 1 % av egenvekten til konvensjonelle fyllmasser. Materialet avlaster grunn med dårlig bæreevne på en god måte. Senere har flere...

  6. Fremre korsbåndskade og utvikling av sekundær artrose

    OpenAIRE

    Holm, Stine

    2013-01-01

    Oppgaven er en blanding av et litteraturstudie og en kohortestudie. I litteraturstudien har jeg sett på hva fremre korsbånd og artrose er, og hvilke risikofaktorer som kan bidra/progrediere utvikling av artrose hos korsbåndsopererte. I kohortestudien har jeg og veilederen sett på forekomsten av artrose hos korsbåndsopererte- 10-20 år etter ACL rekonstruksjon. Ved hjelp av røntgen og klinisk undersøkelse vurderte vi tidligere korsbåndsopererte og grad av artroseforandringer. Vi så også på hvor...

  7. Finansiering av investeringar i immateriella tillgångar

    OpenAIRE

    Voltaire, Christian; Gillebrink, Valerie

    2008-01-01

    Vid en bedömning av ett kreditärende ser banken till projektets företagsekonomiska förutsättningar. För företag som har immateriella tillgångar som de viktigaste tillgångarna i sin redovisning kan det uppstå problem när de ansöker om kredit hos banker. Detta beror på att immateriella tillgångar inte fungerar på samma sätt som materiella och därigenom tillbringar vag säkerhet för en beviljad kredit. Syftet med denna uppsats är att söka finna vad det är som krävs för att ett tjänsteföretag ska ...

  8. American AV: Edgar Dale and the Information Age Classroom.

    Science.gov (United States)

    Acland, Charles R

    2017-01-01

    This article demonstrates how the influential scholar Edgar Dale, alongside a generation of educational technologists, helped build an essential place for AV materials and pedagogical methods in the American classroom. It also shows that, for decades, the Payne Fund philanthropy supported multimedia research agendas that shaped ideas about teaching and technology, far beyond involvement in their famed studies on motion pictures and children in the 1930s. With his writings and research programs, Dale advanced concepts of media experience and systematicity, which came to be understood as common sense to the information society. In so doing he was a leading contributor to the discursive and ideological structure of our age of technological and informational abundance.

  9. UTVÄRDERING AV UTVALDA SD-WAN PRODUKTER

    OpenAIRE

    Åkerblom, Jacob

    2016-01-01

    Denna jämförelsestudie ämnar att undersöka marknadens leverantörer av nätverksutrustning de- finierade som Software Defined Wide Area Networks(SD-WAN). SD-WAN är en innovativ teknik som applicerar virtualisering och Software defined networking koncept i Wide Area Networks (WAN) för att skapa kostnadseffektiva nätverk. Studien har utförts på företaget Curitiba som idag arbetar med konsulttjänster inom utvalda WAN-optimering och SD-WAN-produkter. Arbetets syfte är att utvärdera SD-WAN-lösningar...

  10. EST Table: AV399395 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV399395 NV120168 10/09/28 100 %/139 aa ref|NP_001037386.1| glyceraldehyde-3-phosph...ate dehydrogenase [Bombyx mori] gb|ABA43638.2| glyceraldehyde-3-phosphate dehydrogenase [Bombyx mori] 10/08/28 81 %/139...id:CAA88697.1 10/09/10 89 %/142 aa AGAP009623-PA Protein|3R:37154051:37155049:1|gene:AGAP009623 10/09/10 79 %/139... aa gnl|Amel|GB14798-PA 10/09/10 84 %/139 aa gi|91088023|ref|XP_974181.1| PREDICTED: similar to glyceraldehyde 3-phosphate dehydrogenase [Tribolium castaneum] DN237090 NV12 ...

  11. En språkfundert kompetansemodell for planlegging av undervisning

    Directory of Open Access Journals (Sweden)

    Erik Knain

    2016-04-01

    Full Text Available I utdanningsvitenskapelig litteratur er ulike former for ”literacy” et vedvarende fokus både teoretisk og empirisk. I engelskspråklig naturfagdidaktisk litteratur brukes betegnelsen ”scientific literacy”. Jeg skisserer i denne artikkelen et planleggingsverktøy for undervisning som bygger på en eksplisitt teoretisk modell for deltakelse gjennom språk. Modellen er bindeledd mellom et generalisert kompetansebegrep og planlegging av undervisning ved at den knytter sammen de didaktiske spørsmålene hva, hvem, hvordan og hvorfor med en modell for funksjonell deltakelse. Modellen er spesielt relevant for et allmenndannende ”naturfag for alle”, men favner også et naturfag som fokuserer på utdanning av framtidas naturvitere. Artikkelen retter seg mot naturfag i skolen, men modellen bør kunne anvendes også i andre skolefag. Modellen peker mot et situert og transformativt kompetansebegrep.Nøkkelord: naturfag , kompetanse , diskurs , deltakelse, undervisning og læringAbstractVarious forms of literacy have long been the focus of educational discourses, not the least in science education where the term “scientific literacy” has been an enduring concern for decades. In this article I describe a tool for designing teaching based on a theoretical perspective on participation through language. The model connects a general conception of competence with the planning of teaching. To do so it drowe on the didactical questions of “what, who, how and why”. The model is particularly relevant in a “science for all” perspective but also for the educating of future science specialists. Although school science is the primary focus in this article, the model should be applicable to other school subjects as well. The model opens for a situated and transformative notion of competence.Keywords: scientific literacy, discourse, participation, teaching and learning

  12. Novel measure of electrical dyssynchrony predicts response in cardiac resynchronization therapy: Results from the SMART-AV Trial.

    Science.gov (United States)

    Tereshchenko, Larisa G; Cheng, Alan; Park, Jason; Wold, Nicholas; Meyer, Timothy E; Gold, Michael R; Mittal, Suneet; Singh, Jagmeet; Stein, Kenneth M; Ellenbogen, Kenneth A

    2015-12-01

    Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients. However, not all patients respond to CRT. We hypothesized that a novel measure of electrical dyssynchrony, sum absolute QRST integral (SAI QRST), predicts CRT response independent of QRS duration and morphology. We retrospectively analyzed baseline 12-lead electrocardiograms of SmartDelay Determined AV Optimization: A comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial study participants (N = 234; mean age 67 years; 163 (70%) men; 140 (60%) ischemic cardiomyopathy; mean left ventricular ejection fraction 25%; mean QRS duration 152 ms; 179 (77%) had left bundle branch block). Baseline pre-implant electrocardiograms were digitized, transformed into orthogonal XYZ, and analyzed automatically by customized MATLAB software. SAI QRST was measured as an averaged arithmetic sum of absolute areas under the QRST curve. Patients were followed prospectively 6 months after CRT-defibrillator implantation. Patients with a decrease in left ventricular end-systolic volume ≥15 mL after 6 months of CRT were considered responders. The logistic regression model was adjusted for age, sex, bundle branch block morphology, left ventricular ejection fraction, cardiomyopathy type, and QRS duration. Patients with the high mean SAI QRST (third tertile) had 2.5 times greater odds of response than those with the low mean SAI QRST (first tertile: odds ratio [OR] 2.5; 95% confidence interval [CI] 1.3-5.0; P = .010) and 1.9 times greater than the lower 2 tertiles combined (OR 1.9; 95% CI 1.1-3.5; P = .03). Adjustment for renal function (OR 2.33; 95% CI 1.32-4.11; P = .003) and left ventricular lead position in right anterior oblique and left anterior oblique views (OR 1.7; 95% CI 0.9-3.2; P = .087) did not attenuate association of SAI QRST with outcome. High SAI QRST independently predicts CRT response in the SMART-AV study. Copyright © 2015

  13. Interfacial activity of styrene-butadiene block copolymers in low-density polyethylene/polystyrene blends

    Czech Academy of Sciences Publication Activity Database

    Fortelný, Ivan; Šlouf, Miroslav; Hlavatá, Drahomíra; Sikora, Antonín

    2006-01-01

    Roč. 13, 8-9 (2006), s. 783-799 ISSN 0927-6440 Institutional research plan: CEZ:AV0Z40500505 Keywords : compatibilization * polymer blends * block copolymers Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.788, year: 2006

  14. D-Optimality and D L -optimality criteria for incomplete block designs ...

    African Journals Online (AJOL)

    D-Optimality and DL-optimality criteria for incomplete block designs. A.V Oladugba, M.S Madukaife. Abstract. The adequacy of an experimental design can be determined from the information matrix. The D-optimality criterion is based on the determinant of the information matrix M(ξ) (ξ is any design measure) of a design, ...

  15. Mobitz type I atrio-ventricular block in dengue myocarditis, requiring temporary pacing

    Directory of Open Access Journals (Sweden)

    S. de Mel

    2015-01-01

    Full Text Available We present a case of dengue myocarditis related Mobitz type I atrio-ventricular (A-V block. To our knowledge, this is the first report of such a patient requiring pacing. An early response to methylprednisolone suggests the possibility of a therapeutic role for steroids in these patients.

  16. Mobitz type I atrio-ventricular block in dengue myocarditis, requiring temporary pacing.

    Science.gov (United States)

    de Mel, S; Mowjood, R; Kapuruge, L; de Mel, C; Path, D

    2015-01-01

    We present a case of dengue myocarditis related Mobitz type I atrio-ventricular (A-V) block. To our knowledge, this is the first report of such a patient requiring pacing. An early response to methylprednisolone suggests the possibility of a therapeutic role for steroids in these patients.

  17. Phase structure of symmetric tri-block-copolymers and their blends

    Czech Academy of Sciences Publication Activity Database

    Baldrian, Josef; Steinhart, Miloš; Sikora, Antonín; Amenitsch, H.; Bernstorff, S.

    2005-01-01

    Roč. 13, č. 5 (2005), s. 35-40 ISSN 1230-3666 R&D Projects: GA ČR GA203/03/0611 Institutional research plan: CEZ:AV0Z40500505 Keywords : crystallization * block copolymers * blends Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.397, year: 2005

  18. Self-assembly of POSS-containing block copolymers: fixing the hierarchical structure in networks

    Czech Academy of Sciences Publication Activity Database

    Matějka, Libor; Janata, Miroslav; Pleštil, Josef; Zhigunov, Alexander; Šlouf, Miroslav

    2014-01-01

    Roč. 55, č. 1 (2014), s. 126-136 ISSN 0032-3861 R&D Projects: GA ČR GAP108/12/1459 Grant - others:AV ČR(CZ) M200500903 Institutional support: RVO:61389013 Keywords : block copolymers * self-assembly * POSS Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.562, year: 2014

  19. Conditioned blocking is re-established by neurotransplantation in mature rats

    Czech Academy of Sciences Publication Activity Database

    Morón, I.; Ballesteros, M. A.; Valoušková, Věra; Gallo, M.

    2001-01-01

    Roč. 12, č. 11 (2001), s. 2297-2301 ISSN 0959-4965 R&D Projects: GA MZd NF5400 Institutional research plan: CEZ:AV0Z5011922 Keywords : aging * conditioned blocking * neurotransplantation Subject RIV: FH - Neurology Impact factor: 2.374, year: 2001

  20. Synthesis of highly sulfonated polystyrene-based block copolymers soluble in tetrahydrofuran

    Czech Academy of Sciences Publication Activity Database

    Janata, Miroslav; Kůdela, Vlastimil; Gromadzki, D.; Štěpánek, Petr; Nallet, F.; Diat, O.; Vlček, Petr; Toman, Luděk

    55, - (2006), 1-12 ISSN 1618-7229 R&D Projects: GA ČR GESON/03/E001 Institutional research plan: CEZ:AV0Z40500505 Keywords : polystyrene-block-hydrogenated polyisoprene * sulfonation * acetyl sulfate Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.934, year: 2006 www.e-polymers.org

  1. Unga reumatikers upplevelser av sin sjukdom : En kvalitativ intervjustudie av unga kvinnor och män med reumatism

    OpenAIRE

    Blomberg, Catrin; Helle, Johanna

    2015-01-01

    Syftet med den här studien är att få en inblick i hur unga kvinnor och män med reumatismupplever sin sjukdom. Vi vill jämföra dessa upplevelser mellan män och kvinnor genomatt undersöka om det finns skillnader och likheter i återgivna beskrivningar ochupplevelser. Vi vill undersöka om könsspecifika skillnader på upplevelser kringreumatism skulle kunna kopplas till det faktum att fler kvinnor än män diagnostiseras.Vidare vill vi undersöka om samhällets bemötande av individer med reumatism kank...

  2. Cryoablation of junctional tachycardia at high risk of atrio-ventricular block.

    Science.gov (United States)

    Nadji, G; Hermida, J-S; Kubala, M; Quenum, S; Bakkour, H; Jarry, G

    2008-03-01

    Transcatheter cryoablation is an alternative option for the treatment of supraventricular tachycardia, due to its very low risk of permanent atrio-ventricular block. However, the overcost of cryocatheter and the high recurrence rate of this emerging technology braked its large use. This study reports the results of an approach using cryoablation for the treatment of junctional tachycardia (JT) in selected patients at high risk of atrio-ventricular (AV) block. Out of a series of 199 patients with JT treated by catheter ablation, 26 benefited from cryoablation (mean age 32.8+/-15 years, 15 males). The indications were the presence of an accessory pathway with a high risk of atrio-ventricular block (n=7), a slow pathway difficult to ablate, with a risk of atrio-ventricular block (n=7), a recurrence after a RF procedure, during which a transient atrio-ventricular block has occurred (n=4), and finally patients at young age (n=8). The primary success rate was 92%. No permanent AV block has been reported, neither with RF nor with cryoablation. The recurrence rate at 9+/-10 months was at 29% after cryoablation and 8.6% after RF. In case of AV nodal reentrant tachycardia, the additional cost of cryotherapy catheter has been avoided in 76.85% of cases. The use of a cryotherapy catheter and RF catheter has been necessary for the remaining cases. This study demonstrates that an approach, reserving cryoablation in selected patients at high risk of AV block is an alternative strategy to "the systematic use" of cryotherapy in the ablation of JT with a high efficacy, an excellent safety and a reduced cost.

  3. Right bundle branch block

    DEFF Research Database (Denmark)

    Bussink, Barbara E; Holst, Anders Gaarsdal; Jespersen, Lasse

    2013-01-01

    AimsTo determine the prevalence, predictors of newly acquired, and the prognostic value of right bundle branch block (RBBB) and incomplete RBBB (IRBBB) on a resting 12-lead electrocardiogram in men and women from the general population.Methods and resultsWe followed 18 441 participants included.......5%/2.3% in women, P Right bundle branch block was associated with significantly...... increased all-cause and cardiovascular mortality in both genders with age-adjusted hazard ratios (HR) of 1.31 [95% confidence interval (CI), 1.11-1.54] and 1.87 (95% CI, 1.48-2.36) in the gender pooled analysis with little attenuation after multiple adjustment. Right bundle branch block was associated...

  4. O tornar-se avó no processo de individuação

    Directory of Open Access Journals (Sweden)

    Caroline Dal Ri Kipper

    Full Text Available O tornar-se avó assinala um período de transição no ciclo de vida familiar, marcado por transformações psíquicas significativas para os avós, caracterizando a quarta individuação. Este trabalho teve como objetivo investigar a experiência de tornar-se avó e sua importância no processo de individuação. Foi utilizado delineamento de estudo de caso coletivo. Onze avós maternas, com idades entre 49 e 66 anos, cujas filhas tiveram seu primeiro filho, responderam a uma entrevista semi-estruturada. Todas as avós tinham tido seus primeiros netos e a entrevista referia-se a sua experiência como avós desses netos. Os dados mostraram que o ser avó é uma fonte de renovação e renascimento. O estudo propiciou que as participantes refletissem sobre seus diferentes papéis familiares: avó, mãe, neta e filha. Os dados sugerem que tornar-se avó possibilita que antigos conflitos sejam repensados, renovando antigos vínculos e desejos, o que permite que a avó dê mais um passo rumo à sua individuação.

  5. E-Block: A Tangible Programming Tool with Graphical Blocks

    OpenAIRE

    Danli Wang; Yang Zhang; Shengyong Chen

    2013-01-01

    This paper designs a tangible programming tool, E-Block, for children aged 5 to 9 to experience the preliminary understanding of programming by building blocks. With embedded artificial intelligence, the tool defines the programming blocks with the sensors as the input and enables children to write programs to complete the tasks in the computer. The symbol on the programming block's surface is used to help children understanding the function of each block. The sequence information is transfer...

  6. Rehabilitering efter dekompression och diskoperation - framställandet av en fysioterapeutisk patientanvisning : Ett beställningsarbete av Tölö sjukhus

    OpenAIRE

    Nyberg, Jasmina

    2016-01-01

    Examensarbetet är ett praktiskt inriktat examensarbete med fokus på rehabiliteringen efter en dekompressions- och diskoperation. Det är ett beställningsarbete av Tölö sjukhus med syftet att framställa en fysioterapeutisk patientanvisning. Önskemål från uppdragsgivare var att utforma en tydlig patientanvisning för ryggopererade bestående av skriftliga instruktioner angående postoperativ rehabilitering i form av vardagliga aktiviteter, fysisk aktivitet, ryggens viloställningar, vi...

  7. Contaminated soil concrete blocks

    NARCIS (Netherlands)

    de Korte, A.C.J.; Brouwers, Jos; Limbachiya, Mukesh C.; Kew, Hsein Y.

    2009-01-01

    According to Dutch law the contaminated soil needs to be remediated or immobilised. The main focus in this article is the design of concrete blocks, containing contaminated soil, that are suitable for large production, financial feasible and meets all technical and environmental requirements. In

  8. Making Block Grants Accountable.

    Science.gov (United States)

    Chelimsky, Eleanor

    Methods of accountability are presented in considering the Reagan administration plan to consolidate 84 federal health, education and social service grants into six block grant areas and to cut overall funding. After matching aspects of public criticism with proposal objectives, a rationale is developed for building elements of accountability into…

  9. Linoleum Block Printing Revisited.

    Science.gov (United States)

    Chetelat, Frank J.

    1980-01-01

    The author discusses practical considerations of teaching linoleum block printing in the elementary grades (tool use, materials, motivation) and outlines a sequence of design concepts in this area for the primary, intermediate and junior high grades. A short list of books and audiovisual aids is appended. (SJL)

  10. Effects of Block Scheduling

    Directory of Open Access Journals (Sweden)

    William R. Veal

    1999-09-01

    Full Text Available This study examined the effects of a tri-schedule on the academic achievement of students in a high school. The tri-schedule consists of traditional, 4x4 block, and hybrid schedules running at the same time in the same high school. Effectiveness of the schedules was determined from the state mandated test of basic skills in reading, language, and mathematics. Students who were in a particular schedule their freshman year were tested at the beginning of their sophomore year. A statistical ANCOVA test was performed using the schedule types as independent variables and cognitive skill index and GPA as covariates. For reading and language, there was no statistically significant difference in test results. There was a statistical difference mathematics-computation. Block mathematics is an ideal format for obtaining more credits in mathematics, but the block format does little for mathematics achievement and conceptual understanding. The results have content specific implications for schools, administrations, and school boards who are considering block scheduling adoption.

  11. Coding with Blockly

    CERN Document Server

    Lovett, Amber

    2017-01-01

    "Blockly is a fun, graphical programming language designed to get kids interested in creating their own computer programs. Through simple text written to foster creativity and problem solving, students will the art of innovation. Large, colorful images show students how to complete activities. Additional tools, including a glossary and an index, help students learn new vocabulary and locate information."-- Provided by publisher.

  12. ADVANCED VITRIFICATION SYSTEM (RIC AVS) RESEARCH AND DEVELOPMENT PROJECT

    International Nuclear Information System (INIS)

    Powell, J.R.; Reich, M.

    2003-01-01

    The objective of this AVS testing program is to use bench-scale test equipment to produce a vitrified product at maximum waste loading from the specified AZ-101 waste simulant and conduct a TTT analysis using laboratory scale melts to show compliance with the DOE Waste Acceptance Product Specifications for Vitrified High-Level Waste Forms (WAPS). The vitrified product complies with the following WAPS. A borosilicate glass with a waste loading of 60.9-wt% was produced from a slurry feed of AZ101 simulant. Glass durability testing, glass characterization testing, and testing methodology were performed in accordance with the Department of Energy approved Test Plan. The glass has two crystalline phases and good uniformity of composition. The Product Consistency Test on the 6 location-specific samples are at least 1 to 2 orders of magnitude below the mean PCT results for the EA glass. Standard deviations were less than 10% of measured values. The glass transition temperature averaged 658 ± 9 C. A TTT diagram was produced. There was measured cesium loss of about 2%, and compliance with the Universal Treatment Standards

  13. [Masquerading bundle branch block].

    Science.gov (United States)

    Kukla, Piotr; Baranchuk, Adrian; Jastrzębski, Marek; Bryniarski, Leszek

    2014-01-01

    We here describe a surface 12-lead electrocardiogram (ECG) of a 72-year-old female with a prior history of breast cancer and chemotherapy-induced cardiomyopathy. An echocardiogram revealed left ventricular dysfunction, ejection fraction of 23%, with mild enlarged left ventricle. The 12-lead ECG showed atrial fibrillation with a mean heart rate of about 100 bpm, QRS duration 160 ms, QT interval 400 ms, right bundle branch block (RBBB) and left anterior fascicular block (LAFB). The combination of RBBB features in the precordial leads and LAFB features in the limb leads is known as ''masquerading bundle branch block''. In most cases of RBBB and LAFB, the QRS axis deviation is located between - 80 to -120 degrees. Rarely, when predominant left ventricular forces are present, the QRS axis deviation is near about -90 degrees, turning the pattern into an atypical form. In a situation of RBBB associated with LAFB, the S wave can be absent or very small in lead I. Such a situation is the result of not only purely LAFB but also with left ventricular hypertrophy and/or focal block due to scar (extensive anterior myocardial infarction) or fibrosis (cardiomyopathy). Sometimes, this specific ECG pattern is mistaken for LBBB. RBBB with LAFB may imitate LBBB either in the limb leads (known as 'standard masquerading' - absence of S wave in lead I), or in the precordial leads (called 'precordial masquerading' - absence of S wave in leads V₅ and V₆). Our ECG showed both these types of masquerading bundle branch block - absence of S wave in lead I and in leads V₅ and V₆.

  14. A Study of Mild Steel Corrosion Using Adhatoda Vasica (AV Extract as Inhibitor in Different Acid Medium

    Directory of Open Access Journals (Sweden)

    P. Matheswaran

    2010-01-01

    Full Text Available Corrosion behavior of mild steel in acidic medium using Adhatoda Vasica (AV extract was investigated. The inhibitive effective of Adhatoda Vasica on the corrosion of mild steel in different acidic medium has been studied by weight loss and polarization methods. The Ecorr values are shifted slightly towards negative side in presence of inhibitors which indicate the inhibitors inhibit the corrosion of mild steel in acids solution by controlling both anodic and cathodic reactions due to the blocking of active sites on the metal surface. It is evident that inhibitors bring about considerable polarization of the cathode as well as anode. It was, therefore, inferred that the inhibitive action is of mixed type.

  15. Geologic and Mineralogic Mapping of Av-6 (Gegania) and Av-7 (Lucaria) Quadrangles of Asteroid 4 Vesta

    Science.gov (United States)

    Nathues, A.; Le Corre, L.; Reddy, V.; De Sanctis, M. C.; Williams, D. A.; Garry, W. B.; Yingst, R. A.; Jaumann, R.; Ammannito, E.; Capaccioni, F.; Preusker, F.; Palomba, E.; Roatsch, T.; Tosi, F.; Zambon, F.; Pieters, C. M.; Russell, C. T.; Raymond, C. A.

    2012-04-01

    NASA's Dawn spacecraft arrived at the asteroid 4 Vesta in July 2011 and is now collecting imaging and spectroscopic data during its one-year orbital mission. The maps we present are based on information obtained by the Visible and Infrared Mapping Spectrometer VIR-MS and the multi-color Framing Camera FC. VIR covers the wavelength range between 0.25 to 5.1 µm while FC covers the range 0.4 to 1.0 µm. The VIR instrument has a significant higher spectral resolution than FC but the latter achieves higher spatial resolution data. As part of the geological and mineralogical analysis of the surface, a series of 15 quadrangles have been defined covering the entire surface of Vesta. We report about the mapping results of quadrangle Av-6 (Gegania) and Av-7 (Lucaria). The Gegania quadrangle is dominated by old craters showing no ejecta blankets and rays while several small fresh craters do. The most obvious geologic features are a set of equatorial troughs, a group of three ghost craters of similar diameter (~57 km), an ejecta mantling of the Gegania crater and three smaller craters showing bright and dark ejecta rays. The quadrangle contains two main geologic units: 1) the northern cratered trough terrain and 2) the equatorial ridge and trough terrain. The quadrangle shows moderate variation in Band II center wavelength and Band II depth. FC color ratio variations of some recent craters and their ejecta are linked to the bright and dark material. The bright material is possibly excavated eucritic material while the dark material could be remnants of a CM2 impator(s) or an excavated subsurface layer of endogenic origin. The most prominent geologic features in the Lucaria quadrangle are the 40 km long hill Lucaria Tholus, a set of equatorial troughs, some relatively fresh craters with bright and dark material and mass wasting. The quadrangle contains three main geologic units: 1) the northern cratered trough terrain, 2) the equatorial ridge and trough terrain, and 3) the

  16. Skatte- og konkurransemessige utfordringer i delingsøkonomien : en studie av Airbnb

    OpenAIRE

    Monsen, Jørgen Tvedt; Gundersen, Preben Holme

    2017-01-01

    Delingsøkonomien har vært gjenstand for bemerkelsesverdig vekst i nyere tid. Delingskonseptet omfatter en rekke økonomiske aktiviteter som via en plattform tilrettelegger for effektiv kommunikasjon mellom tilbydere og etterspørrere av underutnyttede ressurser. Gjennom å forsyne overnattingsmarkedet med personers ledige kapasitet av boenheter, har Airbnb blitt en verdensledende delingsaktør. Fremveksten av delingsøkonomien har bidratt til inntektsmuligheter for tilbydere, samtid...

  17. Dialogmøte om teknologi for trenging av fisk i merd

    OpenAIRE

    Henriksen, Kristian; Sunde, Leif Magne; Digre, Hanne; Svendsen, Erik; Rundtop, Per; Erikson, Ulf Gøran

    2013-01-01

    SINTEF Fiskeri og havbruk arrangerte den 19. mars 2013, i samarbeid med Fiskeri- og havbruksnæringens forskningsfond (FHF), et dialogmøte med fokus på teknologi for trenging av fisk i merd. Under møtet ble status for gjeldene teknologi og operasjoner for trenging av fisk i merd, samt resultater fra forskningsprosjekter tilknyttet trengeprosessen, presentert. Videre ble det samlet innspill om utfordringer tilknyttet trenging av fisk i produksjons- og ventemerd fra oppdrettsbedrifter, leverandø...

  18. IAS 40 i ljuset av ägarförhållanden : Värdering av förvaltningsfastigheter i börsnoterade respektive statliga bolag

    OpenAIRE

    Klarin, Olof; Sandell, Johan

    2010-01-01

    Sammanfattning: Redovisningen av förvaltningsfastigheter enligt IAS 40 har tidigare beskrivits i ett stort antal olika vetenskapliga alster. Merparten av dessa har dock tittat på börsnoterade bolag men det finns även andra företag som tillämpar IAS-reglerna. En grupp företag som gör det är de bolag som ägs av svenska staten. Ett av målen med IFRS är att skapa jämförbarhet och då bör inte ägarformen ha någon betydelse för redovisning och värdering. Denna studies syfte är därför att skapa insik...

  19. Utveckling av en Windows Service för databassynkronisering med Microsoft Sync Framework

    OpenAIRE

    Vik, Christian

    2011-01-01

    Detta examensarbete utfördes åt Hogia Ferry Systems. Examensarbetet behandlar utvecklingen av ett synkroniseringsverktyg för databaserna som företagets produkter använder. Lösningen kommer att ersätta ett befintligt system för synkronisering. Fokus för detta projekt ligger på utvecklingen av en synkroniseringstjänst för multipla typer av databaser. Databaserna som stöds är SQL Server, Informix samt Oracle. För utvecklingen av själva synkroniseringen har Microsoft Sync Framework använts. F...

  20. Effekt av å benytte sosiale medier i kampanjer for å fremme sunne levevaner

    OpenAIRE

    Strømme, Hilde

    2014-01-01

    Hensikten med denne systematiske oversikten er å svare på spørsmålet: Hva er effekten av å benytte sosiale medier i kampanjer for å påvirke holdninger, kunnskap og atferd knyttet til sunne levevaner? Metode: Systematiske søk ble gjort i 11 bibliografiske baser. Tilleggssøk ble gjort i Google Scholar. Utvelgelse og vurdering av publikasjoner ble gjort av to personer uavhengig av hverandre. Risiko for systematiske feil ble vurdert med sjekklisten til Cochrane Effective Practice and Organisation...

  1. Frihet, fantasi og utfoldelse: En kvalitativ studie av estetiske arbeidsformer i lærerutdanningene

    Directory of Open Access Journals (Sweden)

    Borghild Brekke

    2017-10-01

    Full Text Available Artikkelen undersøker hva slags forståelse lærerutdannere og lærerstudenter har av estetiske arbeidsformer i undervisningen i lærerutdanningene. Studien er en kvalitativ intervjuundersøkelse blant lærerutdannere og lærerstudenter ved en norsk lærerutdanningsinstitusjon. I lys av danningsteoretisk og didaktisk teori, finner studien at lærerutdannere og lærerstudenters forståelse av estetiske arbeidsformer i undervisningen er kjennetegnet av «frihet» som fravær av tvang og fasit i arbeid med lærestoffet, «fantasi» som bruk av forestillingsevnen slik at kunnskapen blir personlig, og «utfoldelse» som sosialisering inn i et fellesskap gjennom tilbakemeldinger på egen atferd. Til sammen kan informantenes forståelse av de tre aspektene sies å fremheve viktigheten av å utvikle de lærendes autonomi. Artikkelen gir et bidrag til undervisningspraksis i lærerutdanningene, gjennom å gi eksempler på hva estetiske arbeidsformer kan være i en slik sammenheng. Avslutningsvis drøftes funnene opp mot samtidige politiske begrunnelser for bruk av estetiske arbeidsformer i utdanningene.

  2. Functional basis of sinus bradycardia in congenital heart block.

    Science.gov (United States)

    Hu, Keli; Qu, Yongxia; Yue, Yuankun; Boutjdir, Mohamed

    2004-03-05

    Congenital heart block (CHB) is a conduction abnormality characterized by complete atrioventricular (AV) block. CHB affects fetuses and/or newborn of mothers with autoantibodies reactive with ribonucleoproteins 48-kDa SSB/La, 52-kDa SSA/Ro, and 60-kDa SSA/Ro. We recently established animal models of CHB and reported, for the first time, significant sinus bradycardia preceding AV block. This unexpected observation implies that the spectrum of conduction abnormalities extends beyond the AV node to also affect the SA node. To test this hypothesis, we investigated the functional basis of this sinus bradycardia by characterizing the effects of antibodies from mothers with CHB children (positive IgG) on ionic currents that are known to significantly contribute to spontaneous pacing in SA node cells. We recorded L- (I(Ca.L)) and T- (I(Ca.T)) type Ca2+, delayed rectifier K+ (I(K)), hyperpolarization-activated (I(f)) currents, and action potentials (APs) from young rabbit SA node cells. We demonstrated that positive IgG significantly inhibited both I(Ca.T) and I(Ca.L) and induced sinus bradycardia but did not affect I(f) and I(K). Normal IgG from mothers with healthy children did not affect all the currents studied and APs. These results establish that IgG from mothers with CHB children causes substantial inhibition of I(Ca.T) and I(Ca.L), two important pacemaker currents in rabbit SA node cells and point to both I(Ca.T) and I(Ca.L) as major players in the ionic mechanism by which maternal antibodies induce sinus bradycardia in CHB. These novel findings have important clinical significance and suggest that sinus bradycardia may be a potential marker in the detection and prevention of CHB. The full text of this article is available online at http://circres.ahajournals.org

  3. Samtalegrupper for personer med Aspergers syndrom. En kvalitativ studie av hva fagpersoner forteller om planlegging, gjennomføring og effekt av samtalegrupper for personer med Aspergers syndrom

    OpenAIRE

    Jensen, Øyvind

    2014-01-01

    Denne oppgaven er skrevet ut fra problemstillingen: Hvordan beskriver fagpersoner planlegging, gjennomføring og effekt av samtalegrupper for personer med Aspergers syndrom? Den belyser teori om Aspergers syndrom, effekt av samtalegrupper samt andre viktige forhold i tilknytning til samtalegruppe, som kommunikasjon, veiledning og psykoedukasjon. Fire informanter fra nettverket «Nasjonalt fagutviklingsnettverk om psykoedukative grupper for personer med Aspergers syndrom» ble intervjuet, ...

  4. Hvor moralsk tenker fotballspillere? – en empirisk studie av toppfotball

    Directory of Open Access Journals (Sweden)

    Lars Tore Ødegård

    2015-11-01

    Full Text Available Det er en utbredt oppfatning at det økende prestasjonskravet i toppfotball fører til en svekkelse av moral og fair play-holdninger. Men hvordan tenker toppfotballspillere i forhold til ulike dilemmaer som oppstår på banen, og er det forskjeller mellom toppfotballspillere og spillere på lavere nivå?  For å avklare dette gjennomførte vi en empirisk undersøkelse der vi intervjuet spillere og trener i én toppklubb og én breddeklubb. Vi var interessert i to hovedproblemstillinger:  1 Hva tenker fotballspillere på ulike prestasjonsnivå om etikk og moralske dilemmaer i fotball? 2 Hvilke faktorer påvirker spillerne, direkte og indirekte, i deres vurderinger og handlinger? Resultatene fra undersøkelsen viser at det er store forskjeller mellom de to prestasjonsnivåene. Spillerne på breddenivået føler generelt et større ansvar for å opptre ærlig på banen enn hva som er tilfelle på toppnivået. Vi fant 4 spesifikke faktorer i toppfotballen som bidrar til umoralsk opptreden. For det første opplever spillerne en forventning om at de prioriterer resultat foran fair play. For det andre bidrar tilstedeværelsen av supportere på kamper til en slik prioritering. For det tredje vil handlinger som er i strid med fair play signaliseres som akseptable internt i miljøet, selv om de ofte signaliseres som uakseptable overfor media og omverdenen. For det fjerde kan spillere oppleve det som vanskelig å gå i mot trenerens oppfordringer til en pragmatisk og resultatfokusert opptreden.Nøkkelord: moral, etikk, fair play, footballEnglish summary: How morally do football players think? – an empirical study of moral dilemmas in elite footballIt is a common view that the increasing focus on achievement and success in elite football leads to a weakening of moral and fair play attitudes. But how do elite players think and what do they think about different dilemmas that appear on the field, and is there a difference between elite players and lower

  5. Ex vivo, microelectrode analysis of conduction through the AV node of wild-type and Nkx2-5 mutant mouse hearts as guided by a Cx40-eGFP transgenic reporter.

    Science.gov (United States)

    Gazit, Avihu Z; Li, Alex; Choi, Jacob S; Miquerol, Lucile; Jay, Patrick Y

    2014-01-01

    Abstract Mutations of the cardiac transcription factor NKX2-5 cause hypoplastic development of the AV node and conduction block. How the anatomy of the mutant AV node relates to its function is unknown. We thus studied conduction through the AV nodal region in ex vivo preparations of wild-type and Nkx2-5(+/-) mouse hearts in which the central conduction system was highlighted by a transgenic Cx40-eGFP reporter. Fluorescence imaging guided electrode placement and pacing of the inferior and superior approaches to the AV node. Nkx2-5(+/-) hearts had a prolonged atrio-His interval compared to the wild type, consistent with previous in vivo observations. The conduction time to the His bundle from the Cx40(-) AV nodal region that is superior to and immediately adjacent to the Cx40(+) lower node is slightly, but not significantly greater in Nkx2-5(+/-) than wild-type hearts. A novel phenotype was also observed. Pacing the Cx40(-) inferior approach to the AV node with increasing stimulus strength led to progressive shortening of the stimulus-to-His conduction interval in wild-type but not Nkx2-5(+/-) hearts. The strength of pacing at the Cx40(-) superior approach had no effect on the conduction interval in either group. The prolonged AV delay in the Nkx2-5(+/-) heart appears to arise before the Cx40(+) lower node. Whether the pacing phenotype explains the mutant's conduction defect is uncertain, but the observation adds to a number of unique properties of the inferior approach to the AV node.

  6. SUPERFICIAL CERVICAL PLEXUS BLOCK

    Directory of Open Access Journals (Sweden)

    Komang Mega Puspadisari

    2014-01-01

    Full Text Available Superficial cervical plexus block is one of the regional anesthesia in  neck were limited to thesuperficial fascia. Anesthesia is used to relieve pain caused either during or after the surgery iscompleted. This technique can be done by landmark or with ultrasound guiding. The midpointof posterior border of the Sternocleidomastoid was identified and the prosedure done on thatplace or on the level of cartilage cricoid.

  7. Change Around the Block?

    Science.gov (United States)

    Berlin, Joey

    2017-04-01

    Proponents of a block grant or per-capita cap trumpet them as vehicles for the federal government to give the states a capped amount of funding for Medicaid that legislatures would effectively distribute how they see fit. Questions abound as to what capped Medicaid funding would look like, and what effect it would have on the current Medicaid-eligible population, covered services, and physician payments.

  8. Managing access block.

    Science.gov (United States)

    Cameron, Peter; Scown, Paul; Campbell, Donald

    2002-01-01

    There is pessimism regarding the ability of the Acute Health Sector to manage access block for emergency and elective patients. Melbourne Health suffered an acute bed crisis in 2001 resulting in record ambulance diversions and emergency department (ED) delays. We conducted an observational study to reduce access block for emergency patients whilst maintaining elective throughput at Melbourne Health. This involved a clinician-led taskforce using previously proven principles for organisational change to implement 51 actions to improve patient access over a three-month period. The primary outcome measures were ambulance diversion, emergency patients waiting more than 12 hours for an inpatient bed, elective throughput and theatre cancellations. Despite a reduction in multi-day bed numbers all primary objectives were met, ambulance diversion decreased to minimal levels, 12-hour waits decreased by 40% and elective throughput was maintained. Theatre cancellations were also minimised. We conclude that access block can be improved by clinician-led implementation of proven process improvements over a short time frame. The ability to sustain change over the longer term requires further study.

  9. Elevers oppfatning av lærers tilbakemeldingspraksis: om sammenheng mellom graden av VfL-praksis og elevenes opplevde nytte av lærers skriftlige tilbakemeldinger i skriftlig norsk

    Directory of Open Access Journals (Sweden)

    Harald Eriksen

    2017-11-01

    Full Text Available Formålet med denne studien var å undersøke elevers oppfatninger av norsklærerens tilbakemeldingspraksis i skriftlig norsk. På bakgrunn av omfattende internasjonal forskning innen feltet ‘Vurdering for læring’ (VfL er det i denne studien utviklet teoridrevne hypoteser som testes ved å analysere et datasett fra to videregående skoler. Hypotesene er at elevene oppfatter lærers tilbakemelding som mer nyttig hvis den 1 retter seg mot målet med opplæringen, 2 gir elevene informasjon via en forklaring eller instruks om hvordan de skal komme nærmere målet og 3 at lærer legger til rette for bruk av tilbakemeldingen. Strukturell likningsmodellering (SEM av resultater fra en spørreundersøkelse blant elever (N = 213 er brukt som metode til å estimere forholdet mellom de fire latente variablene kriterier, forklaring, bruk og nytte (avhengig variabel. SEM er brukt fordi metoden egner seg til å undersøke sammenhenger i komplekse datasett. Funn er at elevene oppfatter at hvis lærer forklarer hvordan de kan forbedre seg, er dette positivt statistisk assosiert med opplevd nytte. Et mer overraskende funn er at lærerens tilrettelegging for bruk av tilbakemeldinger ikke er signifikant assosiert med opplevd nytte. Resultatene blir diskutert i artikkelen.

  10. Relationship Between Selected Strength and Power Assessments to Peak and Average Velocity of the Drive Block in Offensive Line Play.

    Science.gov (United States)

    Jacobson, Bert H; Conchola, Eric C; Smith, Doug B; Akehi, Kazuma; Glass, Rob G

    2016-08-01

    Jacobson, BH, Conchola, EC, Smith, DB, Akehi, K, and Glass, RG. Relationship between selected strength and power assessments to peak and average velocity of the drive block in offensive line play. J Strength Cond Res 30(8): 2202-2205, 2016-Typical strength training for football includes the squat and power clean (PC) and routinely measured variables include 1 repetition maximum (1RM) squat and 1RM PC along with the vertical jump (VJ) for power. However, little research exists regarding the association between the strength exercises and velocity of an actual on-the-field performance. The purpose of this study was to investigate the relationship of peak velocity (PV) and average velocity (AV) of the offensive line drive block to 1RM squat, 1RM PC, the VJ, body mass (BM), and body composition. One repetition maximum assessments for the squat and PC were recorded along with VJ height, BM, and percent body fat. These data were correlated with PV and AV while performing the drive block. Peal velocity and AV were assessed using a Tendo Power and Speed Analyzer as the linemen fired, from a 3-point stance into a stationary blocking dummy. Pearson product analysis yielded significant (p ≤ 0.05) correlations between PV and AV and the VJ, the squat, and the PC. A significant inverse association was found for both PV and AV and body fat. These data help to confirm that the typical exercises recommended for American football linemen is positively associated with both PV and AV needed for the drive block effectiveness. It is recommended that these exercises remain the focus of a weight room protocol and that ancillary exercises be built around these exercises. Additionally, efforts to reduce body fat are recommended.

  11. Effects of AV-delay optimization on hemodynamic parameters in patients with VDD pacemakers.

    Science.gov (United States)

    Krychtiuk, Konstantin A; Nürnberg, Michael; Volker, Romana; Pachinger, Linda; Jarai, Rudolf; Freynhofer, Matthias K; Wojta, Johann; Huber, Kurt; Weiss, Thomas W

    2014-05-01

    Atrioventricular (AV) delay optimization improves hemodynamics and clinical parameters in patients treated with cardiac resynchronization therapy and dual-chamber-pacemakers (PM). However, data on optimizing AV delay in patients treated with VDD-PMs are scarce. We, therefore, investigated the acute and chronic effects of AV delay optimization on hemodynamics in patients treated with VDD-PMs due to AV-conduction disturbances. In this prospective, single-center interventional trial, we included 64 patients (38 men, 26 women, median age: 77 (70-82) years) with implanted VDD-PM. AV-delay optimization was performed using a formula based on the surface electrocardiogram (ECG). Hemodynamic parameters (stroke volume (SV), cardiac output (CO), heart rate (HR), and blood pressure (BP)) were measured at baseline and follow-up after 3 months using impedance cardiography. Using an ECG formula for AV-delay optimization, the AV interval was decreased from 180 (180-180) to 75 (75-100) ms. At baseline, AV-delay optimization led to a significant increase of both SV (71.3 ± 15.8 vs. 55.3 ± 12.7 ml, p AV delay vs. nominal AV interval, respectively) and CO (5.1 ± 1.4 vs. 3.9 ± 1.0 l/min, p AV-delay optimization in patients treated with VDD-PMs exhibits immediate beneficial effects on hemodynamic parameters that are sustained for 3 months.

  12. Human eye localization using the modified Hough transform

    Czech Academy of Sciences Publication Activity Database

    Dobeš, M.; Martínek, J.; Skoupil, D.; Dobešová, Z.; Pospíšil, Jaroslav

    2006-01-01

    Roč. 117, - (2006), s. 468-473 ISSN 0030-4026 Institutional research plan: CEZ:AV0Z10100522 Keywords : human eye localization * modified Hough transform * eye iris and eyelid shape determination Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.585, year: 2006

  13. Litterær kompetanse - portrett av tre lesarar

    Directory of Open Access Journals (Sweden)

    Hallvard Kjelen

    2015-08-01

    Full Text Available Artikkelen drøfter eit sentralt problemfelt innom litteraturdidaktikken, nemleg tilhøvet mellom litterær lesing som fagleg kompetanse og litterær lesing som oppleving. Problemfeltet er særleg knytt til Louise Rosenblatts arbeid. Ho viser ved hjelp av omgrepa efferent og estetisk lesing korleis det er ei utfordring for litteraturlæraren å utvikle ei litteraturundervisning som i tilstrekkeleg grad tek omsyn til kjensler og røynsler. I ein litteraturteoretisk kontekst er subjektive responsar på litterære tekstar irrelevante, men i ein litteraturdidaktisk kontekst er subjektive responsar høgst relevante. Denne artikkelen bidrar inn i diskusjon-en mellom anna ved å trekkje inn meir empirisk basert litteraturteori som referanseramme. Artikkelen presenterer tre lesarars litterære responsar, og viser korleis kunnskap om individuelle lesarresponsar kan vere utgangspunkt for ei litteraturundervisning som balanserer ei fagleg tilnærming til litteratur opp mot ei meir opplevingsbasert tilnærming.Emneord: Litteraturundervisning, litterær kompetanse, empirisk litteraturteori, lesarresponsAbstractThe article discusses a key issue in literature didactics, namely the relation between literary reading as an academic competence, and literary reading as an experience. The discussion draws heavily on Louise Rosenblatt’s work. By using the concepts efferent and aesthetic reading, she shows how it is a challenge for the teacher of literature to develop literature teaching that adequately takes emotions and experience into account. In a literature-theoretical context, subjective responses to literary texts are irrelevant; but in a didactics context, the subjective responses are highly relevant.  This article contributes to the discussion by bringing in a more empirically based literature theory as a frame of reference. The article presents three readers’ literary responses, and shows how knowledge of individual reader responses can be the basis for

  14. AVS/Express (application visualization system) user's guide

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Katsumi [Research Organization for Information Science Technology, Tokai, Ibaraki (Japan); Kume, Etsuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-09-01

    Computer and network environment for image processing has been developed and maintained under the course of establishing a distributed processing environment by the information system operating division. We introduced a server for image processing, AVS/Express for image processing software and Stereo viewing system. This report summarizes the information to use AVS/Express efficiently in the computer environment for image processing. (author)

  15. Pilot Implementation and Preliminary Evaluation of START:AV Assessments in Secure Juvenile Correctional Facilities.

    Science.gov (United States)

    Desmarais, Sarah L; Sellers, Brian G; Viljoen, Jodi L; Cruise, Keith R; Nicholls, Tonia L; Dvoskin, Joel A

    2012-01-01

    The Short-Term Assessment of Risk and Treatability: Adolescent Version (START:AV) is a new structured professional judgment guide for assessing short-term risks in adolescents. The scheme may be distinguished from other youth risk assessment and treatment planning instruments by its inclusion of 23 dynamic factors that are each rated for both vulnerability and strength. In addition, START:AV is also unique in that it focuses on multiple adverse outcomes-namely, violence, self-harm, suicide, unauthorized leave, substance abuse, self-neglect, victimization, and general offending-over the short-term (i.e., weeks to months) rather than long-term (i.e., years). This paper describes a pilot implementation and preliminary evaluation of START:AV in three secure juvenile correctional facilities in the southern United States. Specifically, we examined the descriptive characteristics and psychometric properties of START:AV assessments completed by 21 case managers on 291 adolescent offenders (250 boys and 41 girls) at the time of admission. Results provide preliminary support for the feasibility of completing START:AV assessments as part of routine practice. Findings also highlight differences in the characteristics of START:AV assessments for boys and girls and differential associations between the eight START:AV risk domains. Though results are promising, further research is needed to establish the reliability and validity of START:AV assessments completed in the field.

  16. A-V Fistulae from Arrow Injuries: A Report of Two Cases ...

    African Journals Online (AJOL)

    Of these, one involved the temporal vessels, which led to a temporo-temporal A-V fistula causing the patient continuous noisy headache. The late complication was only recognized about two years post injury. Another arrow shot injury involved femoral vessels and resulted in femoro-femoral A-V fistula, which came to be ...

  17. InterProScan Result: AV401888 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV401888 AV401888_3_ORF1 2F04E8AA567F7BCF PANTHER PTHR11511 INSECT HEMOCYANIN-RELAT...ED 1.5e-119 T IPR013788 Arthropod hemocyanin/insect LSP Molecular Function: oxygen transporter activity (GO:0005344)|Biological Process: transport (GO:0006810) ...

  18. InterProScan Result: AV402282 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV402282 AV402282_2_ORF1 D1F0DCC6A8296985 PANTHER PTHR11511 INSECT HEMOCYANIN-RELAT...ED 5e-97 T IPR013788 Arthropod hemocyanin/insect LSP Molecular Function: oxygen transporter activity (GO:0005344)|Biological Process: transport (GO:0006810) ...

  19. InterProScan Result: AV399740 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV399740 AV399740_3_ORF2 7A42A41D4F3F6388 PFAM PF00067 p450 1.2e-19 T IPR001128 Cytochrome P450 Molecular... Function: monooxygenase activity (GO:0004497)|Molecular Function: iron ion binding (GO:0005506)|Molecular... Function: electron carrier activity (GO:0009055)|Molecular Function: heme binding (GO:0020037) ...

  20. InterProScan Result: AV399409 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available 429 Baculovirus LEF-11 Biological Process: viral infectious cycle (GO:0019058)|Biological Process: regulation of transcription (GO:0045449) ... ...AV399409 AV399409_1_ORF2 07DC81A7C7B2FA42 PFAM PF06385 Baculo_LEF-11 3e-33 T IPR009

  1. Paving block study : final report.

    Science.gov (United States)

    1971-10-01

    The Louisiana Department of Highways has conducted field tests with an experimental revetment consisting of cellular concrete revetment blocks used in conjunction with plastic filter cloth and/or vegetation such as grass or vines. The precast blocks ...

  2. Habitat Blocks and Wildlife Corridors

    Data.gov (United States)

    Vermont Center for Geographic Information — Habitat blocks are areas of contiguous forest and other natural habitats that are unfragmented by roads, development, or agriculture. Vermonts habitat blocks are...

  3. Demographic Data - MDC_Block

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — A polygon feature class of Miami-Dade Census 2000 Blocks. Census blocks are areas bounded on all sides by visible and/or invisible features shown on a map prepared...

  4. Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family

    DEFF Research Database (Denmark)

    Nilsson, Stefan K; Lookene, Aivar; Beckstead, Jennifer A

    2007-01-01

    Apolipoprotein A-V is a potent modulator of plasma triacylglycerol levels. To investigate the molecular basis for this phenomenon we explored the ability of apolipoprotein A-V, in most experiments complexed to disks of dimyristoylphosphatidylcholine, to interact with two members of the low density...... lipoprotein receptor family, the low density lipoprotein receptor-related protein and the mosaic type-1 receptor, SorLA. Experiments using surface plasmon resonance showed specific binding of both free and lipid-bound apolipoprotein A-V to both receptors. The binding was calcium dependent and was inhibited......, apolipoprotein A-V (Arg210Glu/Lys211Gln), showed decreased binding to heparin and decreased ability to bind the low density lipoprotein receptor-related protein. Association of apolipoprotein A-V with the low density lipoprotein receptor-related protein or SorLA resulted in enhanced binding of human chylomicrons...

  5. Blocking the Hawking radiation

    DEFF Research Database (Denmark)

    Autzen, M.; Kouvaris, C.

    2014-01-01

    grows after its formation (and eventually destroys the star) instead of evaporating. The fate of the black hole is dictated by the two opposite mechanics, i.e., accretion of nuclear matter from the center of the star and Hawking radiation that tends to decrease the mass of the black hole. We study how...... the assumptions for the accretion rate can in fact affect the critical mass beyond which a black hole always grows. We also study to what extent degenerate nuclear matter can impede Hawking radiation due to the fact that emitted particles can be Pauli blocked at the core of the star....

  6. How Artists Overcome Creative Blocks.

    Science.gov (United States)

    Hirst, Barbara

    1992-01-01

    Six practicing artists were interviewed about how they overcome creative blocks. Their responses indicated that feelings of self-doubt, fear, and depression accompany blocks but that relaxing and working on new directions and playing ideas off a supportive person helped to overcome such blocks. (DB)

  7. Block Scheduling in High Schools.

    Science.gov (United States)

    Irmsher, Karen

    1996-01-01

    Block Scheduling has been considered a cure for a lengthy list of educational problems. This report reviews the literature on block schedules and describes some Oregon high schools that have integrated block scheduling. Major disadvantages included resistance to change and requirements that teachers change their teaching strategies. There is…

  8. Abdominal wall blocks in adults

    DEFF Research Database (Denmark)

    Neimann, Jens Dupont Børglum; Gögenür, Ismail; Bendtsen, Thomas F.

    2016-01-01

    Purpose of review Abdominal wall blocks in adults have evolved much during the last decade; that is, particularly with the introduction of ultrasound-guided (USG) blocks. This review highlights recent advances of block techniques within this field and proposes directions for future research.  Rec...

  9. Effect of block composition on thermal properties and melt viscosity of poly[2-(dimethylaminoethyl methacrylate], poly(ethylene oxide and poly(propylene oxide block co-polymers

    Directory of Open Access Journals (Sweden)

    2011-09-01

    Full Text Available To modify the rheological properties of certain commercial polymers, a set of block copolymers were synthesized through oxyanionic polymerization of 2-(dimethylaminoethyl methacrylate to the chain ends of commercial prepolymers, namely poly(ethylene oxide (PEO, poly(ethylene oxide-block-poly(propylene oxide-block-poly(ethylene oxide (PEO-PPO-PEO, and poly(propylene oxide (PPO. The formed block copolymers were analysed with size exclusion chromatography and nuclear magnetic resonance spectroscopy in order to confirm block formation. Thermal characterization of the resulting polymers was done with differential scanning calorimetry. Thermal transition points were also confirmed with rotational rheometry, which was primarily used to measure melt strength properties of the resulting block co-polymers. It was observed that the synthesised poly[2-(dimethylaminoethyl methacrylate]-block (PDM affected slightly the thermal transition points of crystalline PEO-block but the influence was stronger on amorphous PPO-blocks. Frequency sweeps measured above the melting temperatures for the materials confirmed that the pre-polymers (PEO and PEO-PPO-PEO behave as Newtonian fluids whereas polymers with a PDM block structure exhibit clear shear thinning behaviour. In addition, the PDM block increased the melt viscosity when compared with that one of the pre-polymer. As a final result, it became obvious that pre-polymers modified with PDM were in entangled form, in the melted state as well in the solidified form.

  10. In vivo retention of18F-AV-1451 in corticobasal syndrome.

    Science.gov (United States)

    Smith, Ruben; Schöll, Michael; Widner, Håkan; van Westen, Danielle; Svenningsson, Per; Hägerström, Douglas; Ohlsson, Tomas; Jögi, Jonas; Nilsson, Christer; Hansson, Oskar

    2017-08-22

    To study the usefulness of 18 F-AV-1451 PET in patients with corticobasal syndrome (CBS). We recruited 8 patients with CBS, 17 controls, 31 patients with Alzheimer disease (AD), and 11 patients with progressive supranuclear palsy (PSP) from the Swedish BioFINDER study. All patients underwent clinical assessment, 18 F-AV-1451 PET, MRI, and quantification of β-amyloid pathology. A subset of participants also underwent 18 F-FDG-PET. In the 8 patients with CBS, 6 had imaging findings compatible with the corticobasal degeneration pathology and 2 with typical AD pathology. In the 6 patients with CBS without typical AD pathology, there were substantial retentions of 18 F-AV-1451 in the motor cortex, corticospinal tract, and basal ganglia contralateral to the most affected body side. These patients could be clearly distinguished from patients with AD dementia or PSP using 18 F-AV-1451. However, cortical atrophy was more widespread than the cortical retention of 18 F-AV1451 in these CBS cases, and cortical AV-1451 uptake did not correlate with cortical thickness or glucose hypometabolism. These results are in sharp contrast to AD dementia, where 18 F-AV-1451 retention was more widespread than cortical atrophy, and correlated well with cortical thickness and hypometabolism. Patients with CBS without typical AD pathology exhibited AV-1451 retention in the motor cortex, corticospinal tract, and basal ganglia contralateral to the affected body side, clearly different from controls and patients with AD dementia or PSP. However, cortical atrophy measured with MRI and decreased 18 F-fluorodeoxyglucose uptake were more widespread than 18 F-AV-1451 uptake and probably represent earlier, yet less specific, markers of CBS. This study provides Class III evidence that 18 F-AV-1451 PET distinguishes between CBS and AD or PSP. Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.

  11. [18F]AV-1451 tau positron emission tomography in progressive supranuclear palsy.

    Science.gov (United States)

    Whitwell, Jennifer L; Lowe, Val J; Tosakulwong, Nirubol; Weigand, Stephen D; Senjem, Matthew L; Schwarz, Christopher G; Spychalla, Anthony J; Petersen, Ronald C; Jack, Clifford R; Josephs, Keith A

    2017-01-01

    The [ 18 F]AV-1451 positron emission tomography ligand allows the in vivo assessment of tau proteins in the brain. It shows strong binding in Alzheimer's dementia, but little is known about how it performs in progressive supranuclear palsy, a primary 4R tauopathy. The objectives of this study were to determine whether [ 18 F]AV-1451 uptake can be observed in progressive supranuclear palsy and to characterize the regional distribution when compared with controls and Alzheimer's dementia. [ 18 F]AV-1451 positron emission tomography was performed in 10 patients with probable progressive supranuclear palsy. These patients were age- and gender-matched to 50 controls and 10 Alzheimer's dementia patients who had undergone identical [ 18 F]AV-1451 imaging. Regional comparisons of [ 18 F]AV-1451 uptake were performed across the whole brain using region-of-interest and voxel-level analyses, and correlations between regional [ 18 F]AV-1451 and the progressive supranuclear palsy rating scale were assessed. An elevated [ 18 F]AV-1451 signal was observed in progressive supranuclear palsy when compared with controls in the pallidum, midbrain, dentate nucleus of the cerebellum, thalamus, caudate nucleus, and frontal regions. Signal in the cerebellar dentate and pallidum were also greater in progressive supranuclear palsy when compared with Alzheimer's dementia. Conversely, the [ 18 F]AV-1451 signal across the cortex was higher in Alzheimer's dementia when compared with progressive supranuclear palsy. The [ 18 F]AV-1451 signal in a number of regions correlated with the progressive supranuclear palsy rating scale. Progressive supranuclear palsy is associated with an elevated [ 18 F]AV-1451 signal in a characteristic and distinct regional pattern that correlates with disease severity and differs from the patterns observed in Alzheimer's dementia. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

  12. Interfacial Modifiers

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Ina; French, Roger H.

    2018-03-19

    Our project objective in the first and only Budget Period was to demonstrate the potential of nm-scale organofunctional silane coatings as a method of extending the lifetime of PV materials and devices. Specifically, the target was to double the lifetime performance of a laminated Cu(In,Ga)Se2 (CIGS) cell under real-world and accelerated aging exposure conditions. Key findings are that modification of aluminum-doped zinc oxide (AZO) films (materials used as transparent conductive oxide (TCO) top contacts) resulted in decreased degradation of optical and electrical properties under damp heat (DH) exposure compared to un-modified AZO. The most significant finding is that modification of the AZO top contact of full CIGS devices resulted in significantly improved properties under DH exposure compared to un-modified devices, by a factor of 4 after 1000 h. Results of this one-year project have demonstrated that surface functionalization is a viable pathway for extending the lifetime of state-of-the-art CIGS devices.

  13. Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.

    Science.gov (United States)

    Xia, Chenjie; Makaretz, Sara J; Caso, Christina; McGinnis, Scott; Gomperts, Stephen N; Sepulcre, Jorge; Gomez-Isla, Teresa; Hyman, Bradley T; Schultz, Aaron; Vasdev, Neil; Johnson, Keith A; Dickerson, Bradford C

    2017-04-01

    Previous postmortem studies have long demonstrated that neurofibrillary tangles made of hyperphosphorylated tau proteins are closely associated with Alzheimer disease clinical phenotype and neurodegeneration pattern. Validating these associations in vivo will lead to new diagnostic tools for Alzheimer disease and better understanding of its neurobiology. To examine whether topographical distribution and severity of hyperphosphorylated tau pathologic findings measured by fluorine 18-labeled AV-1451 ([18F]AV-1451) positron emission tomographic (PET) imaging are linked with clinical phenotype and cortical atrophy in patients with Alzheimer disease. This observational case series, conducted from July 1, 2012, to July 30, 2015, in an outpatient referral center for patients with neurodegenerative diseases, included 6 patients: 3 with typical amnesic Alzheimer disease and 3 with atypical variants (posterior cortical atrophy, logopenic variant primary progressive aphasia, and corticobasal syndrome). Patients underwent [18F]AV-1451 PET imaging to measure tau burden, carbon 11-labeled Pittsburgh Compound B ([11C]PiB) PET imaging to measure amyloid burden, and structural magnetic resonance imaging to measure cortical thickness. Seventy-seven age-matched controls with normal cognitive function also underwent structural magnetic resonance imaging but not tau or amyloid PET imaging. Tau burden, amyloid burden, and cortical thickness. In all 6 patients (3 women and 3 men; mean age 61.8 years), the underlying clinical phenotype was associated with the regional distribution of the [18F]AV-1451 signal. Furthermore, within 68 cortical regions of interest measured from each patient, the magnitude of cortical atrophy was strongly correlated with the magnitude of [18F]AV-1451 binding (3 patients with amnesic Alzheimer disease, r = -0.82; P Alzheimer disease, r = -0.51; P Alzheimer disease neuropathologic condition with clinically significant neurodegeneration, which will

  14. Program structure-based blocking

    Science.gov (United States)

    Bertolli, Carlo; Eichenberger, Alexandre E.; O'Brien, John K.; Sura, Zehra N.

    2017-09-26

    Embodiments relate to program structure-based blocking. An aspect includes receiving source code corresponding to a computer program by a compiler of a computer system. Another aspect includes determining a prefetching section in the source code by a marking module of the compiler. Yet another aspect includes performing, by a blocking module of the compiler, blocking of instructions located in the prefetching section into instruction blocks, such that the instruction blocks of the prefetching section only contain instructions that are located in the prefetching section.

  15. BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling.

    Science.gov (United States)

    Saxon, Jacob G; Baer, Daniel R; Barton, Julie A; Hawkins, Travis; Wu, Bingruo; Trusk, Thomas C; Harris, Stephen E; Zhou, Bin; Mishina, Yuji; Sugi, Yukiko

    2017-10-01

    Distal outgrowth, maturation and remodeling of the endocardial cushion mesenchyme in the atrioventricular (AV) canal are the essential morphogenetic events during four-chambered heart formation. Mesenchymalized AV endocardial cushions give rise to the AV valves and the membranous ventricular septum (VS). Failure of these processes results in several human congenital heart defects. Despite this clinical relevance, the mechanisms governing how mesenchymalized AV endocardial cushions mature and remodel into the membranous VS and AV valves have only begun to be elucidated. The role of BMP signaling in the myocardial and secondary heart forming lineage has been well studied; however, little is known about the role of BMP2 expression in the endocardial lineage. To fill this knowledge gap, we generated Bmp2 endocardial lineage-specific conditional knockouts (referred to as Bmp2 cKO Endo ) by crossing conditionally-targeted Bmp2 flox/flox mice with a Cre-driver line, Nfatc1 Cre , wherein Cre-mediated recombination was restricted to the endocardial cells and their mesenchymal progeny. Bmp2 cKO Endo mouse embryos did not exhibit failure or delay in the initial AV endocardial cushion formation at embryonic day (ED) 9.5-11.5; however, significant reductions in AV cushion size were detected in Bmp2 cKO Endo mouse embryos when compared to control embryos at ED13.5 and ED16.5. Moreover, deletion of Bmp2 from the endocardial lineage consistently resulted in membranous ventricular septal defects (VSDs), and mitral valve deficiencies, as evidenced by the absence of stratification of mitral valves at birth. Muscular VSDs were not found in Bmp2 cKO Endo mouse hearts. To understand the underlying morphogenetic mechanisms leading to a decrease in cushion size, cell proliferation and cell death were examined for AV endocardial cushions. Phospho-histone H3 analyses for cell proliferation and TUNEL assays for apoptotic cell death did not reveal significant differences between control and

  16. Production of Polyclonal Antiobies to a Recombinant Potato Mop-top Virus Non-structural Triple Gene Block Protein l

    Czech Academy of Sciences Publication Activity Database

    Čeřovská, Noemi; Filigarová, Marie; Pečenková, Tamara

    2006-01-01

    Roč. 154, - (2006), s. 422-427 ISSN 0931-1785 R&D Projects: GA ČR GA522/04/1329 Institutional research plan: CEZ:AV0Z50380511 Keywords : Potato mop-top virus * recombinant protein * triple gene block * polyclonal antibodies Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 0.817, year: 2006

  17. Anionic polymerization of acrylates. XIV. Synthesis of MMA/acrylate block copolymers initiated with ester-enolate/tert-alkoxide complex

    Czech Academy of Sciences Publication Activity Database

    Vlček, Petr; Čadová, Eva; Kříž, Jaroslav; Látalová, Petra; Janata, Miroslav; Toman, Luděk; Masař, Bohumil

    2005-01-01

    Roč. 46, č. 14 (2005), s. 4991-5000 ISSN 0032-3861 Institutional research plan: CEZ:AV0Z4050913 Keywords : ligated anionic polymerization * (meth)acrylates * block copolymers Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.849, year: 2005

  18. Modification of poly(styrene-block-butadiene-block-styrene) [SBS] with phosphorus containing fire retardants

    DEFF Research Database (Denmark)

    Chernyy, Sergey; Ullah, Saif; Jomaas, Grunde

    2015-01-01

    An elaborate survey of the chemical modification methods for endowing highly flammable SBS with increased fire resistant properties by means of chemical modification of the polymer backbone with phosphorus containing fire retardant species is presented. Optimal conditions for free radical addition...... resulting in 20 mol% of poly(butadiene) block modification. Based on TGA results, organophosporus-modified SBS was found to be amenable to charring – a property which correlated directly with the reduced flammability of the modified polymer observed in Cone Calorimetry tests. Furthermore, conceptually novel...... application of the H3PO4 modified SBS as a fire retardant additive for bitumen material, in combination with synergetic melamine species, offered 25% better self-extinguishing properties of such formulation already at a low loading level of the fire retardant components (3.5 wt.%)....

  19. Jämförelse av vertikala accelerationer av järnvägsbroar för höghastighetståg.

    OpenAIRE

    Shoaibi, Martin

    2014-01-01

    Under de senaste decennierna parallellt med klimatdiskussionen har det vuxit fram ett stort intresse för höghastighetståg och en förbättrad infrastruktur i Sverige. I delar av Europa men speciellt i Kina och Japan har utvecklingen av höghastighetståg fått ett enormt lyft. Ett problem vid höjda tåghastigheter är att broarna vid en kombination av låg massa och låg egenfrekvens riskerar att orsaka resonans och höga accelerationsnivåer vid passage. Ballastspår är namnet för det traditionella järn...

  20. Performance study of radiation detectors based on semi-insulating GaAs with P+homo- and heterojunction blocking electrode

    Czech Academy of Sciences Publication Activity Database

    Dubecky, F.; Hulicius, Eduard; Frigeri, P.; Perd´ochová-Šagátová, A.; Zat´ko, B.; Hubík, Pavel; Gombia, E.; Boháček, P.; Pangrác, Jiří; Franchi, S.; Nečas, V.

    2006-01-01

    Roč. 563, - (2006), s. 159-162 ISSN 0168-9002 R&D Projects: GA AV ČR(CZ) IAA1010404 Grant - others:Slovak Grant Agency for Science(SK) 2/4151/24 Institutional research plan: CEZ:AV0Z10100521 Keywords : GaAs radiation detector * blocking electrode * P + -N homojunction and heterojunction * gamma irradiation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.185, year: 2006

  1. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block.

    Science.gov (United States)

    Simon, A M; Goodenough, D A; Paul, D L

    1998-02-26

    Activation of cardiac muscle is mediated by the His-Purkinje system, a discrete pathway containing fast-conducting cells (Purkinje fibers) which coordinate the spread of excitation from the atrioventricular node (AV node) to ventricular myocardium [1]. Although pathologies of this specialized conduction system are common in humans, especially among the elderly [2], their molecular bases have not been defined. Gap junctions are present at appositions between Purkinje fibers and could provide a mechanism for propagating impulses between these cells [3]. Studies of the expression of connexins - the family of proteins from which gap junctions are formed - reveal that connexin40 (Cx40) is prominent in the conduction system [4]. In order to study the role of gap junction communication in cardiac conduction, we generated mice that lack Cx40. Using electrocardiographic analysis, we show that Cx40 null mice have cardiac conduction abnormalities characteristic of first-degree atrioventricular block with associated bundle branch block. Thus, gap junctions are essential for the rapid conduction of impulses in the His-Purkinje system.

  2. Block copolymer investigations

    Science.gov (United States)

    Yufa, Nataliya A.

    The research presented in this thesis deals with various aspects of block copolymers on the nanoscale: their behavior at a range of temperatures, their use as scaffolds, or for creation of chemically striped surfaces, as well as the behavior of metals on block copolymers under the influence of UV light, and the healing behavior of copolymers. Invented around the time of World War II, copolymers have been used for decades due to their macroscopic properties, such as their ability to be molded without vulcanization, and the fact that, unlike rubber, they can be recycled. In recent years, block copolymers (BCPs) have been used for lithography, as scaffolds for nano-objects, to create a magnetic hard drive, as well as in photonic and other applications. In this work we used primarily atomic force microscopy (AFM) and transmission electron microscopy (TEM), described in Chapter II, to conduct our studies. In Chapter III we demonstrate a new and general method for positioning nanoparticles within nanoscale grooves. This technique is suitable for nanodots, nanocrystals, as well as DNA. We use AFM and TEM to demonstrate selective decoration. In Chapters IV and V we use AFM and TEM to study the structure of polymer surfaces coated with metals and self-assembled monolayers. We describe how the surfaces were created, exhibit their structure on the nanoscale, and prove that their macroscopic wetting properties have been altered compared to the original polymer structures. Finally, Chapters VI and VII report out in-situ AFM studies of BCP at high temperatures, made possible only recently with the invention of air-tight high-temperature AFM imaging cells. We locate the transition between disordered films and cylinders during initial ordering. Fluctuations of existing domains leading to domain coarsening are also described, and are shown to be consistent with reptation and curvature minimization. Chapter VII deals with the healing of PS-b-PMMA following AFM-tip lithography or

  3. Sampling method, storage and pretreatment of sediment affect AVS concentrations with consequences for bioassay responses

    Energy Technology Data Exchange (ETDEWEB)

    Lange, H.J. de [Aquatic Ecology and Water Quality Management Group, Wageningen University, Wageningen University and Research Centre, P.O. Box 8080, 6700 DD, Wageningen (Netherlands); Centre for Ecosystem Studies, Alterra, Wageningen University and Research Centre, P.O. Box 47, 6700 AA, Wageningen (Netherlands)], E-mail: marieke.delange@wur.nl; Griethuysen, C. van; Koelmans, A.A. [Aquatic Ecology and Water Quality Management Group, Wageningen University, Wageningen University and Research Centre, P.O. Box 8080, 6700 DD, Wageningen (Netherlands)

    2008-01-15

    Sediment treatment and sediment storage may alter sediment toxicity, and consequently biotic response. Purpose of our study was to combine these three aspects (treatment-toxicity-biotic response) in one integrated approach. We used Acid Volatile Sulfide (AVS) concentrations as a proxy of the disturbance of the sediment. AVS and Simultaneously Extracted Metal (SEM) concentrations were compared to bioassay responses with the freshwater benthic macroinvertebrate Asellus aquaticus. Storage conditions and sediment treatment affected AVS but not SEM levels. AVS can be used as a proxy for sediment disturbance. The best way to pretreat the sediment for use in a bioassay in order to maintain initial AVS conditions was to sample the sediment with an Ekman grab, immediately store it in a jar without headspace, and freeze it as soon as possible. In a survey using seven different sediments, bioassay responses of A. aquaticus were correlated with SEM and AVS characteristics. - Change in AVS is a good proxy for sediment disturbance and combined with SEM it can be used as a suitable predictor for biotic effects of sediment contamination.

  4. Mot en professionalisering av det pedagogiska ledarskapet vid Umeå universitet

    Directory of Open Access Journals (Sweden)

    Sven B Eriksson

    2013-01-01

    Full Text Available Det pedagogiska ledarskapet inom högre utbildning fokuseras allt mer. Det understryks genom att flera lärosäten föreskriver såväl att pedagogiska ledare ska finnas på olika nivåer, som vilka övergripande uppgifter dessa ska ha. Denna artikel är ett resultat av en fallstudie av hur de tillägnade kunskaperna och färdigheterna från kursen Pedagogiskt ledarskap, en kurs för målgruppen studierektorer/pedagogiskt ansvariga eller motsvarande arrangerad av Universitetspedagogiskt centrum, har bidragit till deltagarnas professionalisering av det pedagogiska ledarskapet ett år efter kursens slut. Fallstudien genomfördes genom gruppintervjuer. Respondenterna uttryckte att de fått ett stärkt självförtroende i rollen som pedagogiska ledare samt att kursen bidrog till en professionalisering av rollen som pedagogiska ledare genom att stärka identiteten, att skapa en början till en handlingsetik bestående av delvis delade värderingar kring det pedagogiska ansvaret samt ge utbildning och träning i färdigheter som har sin grund i teoretisk kunskap. Kursen Pedagogiskt ledarskap ger därmed ett stöd i en process mot en professionalisering av det pedagogiska ledarskapet vid Umeå universitet.

  5. Highly Stable Foams from Block Oligomers Synthesized by Enzymatic Reactions

    NARCIS (Netherlands)

    Sagis, L.M.C.; Boeriu, C.G.; Frissen, A.E.; Schols, H.A.; Wierenga, P.A.

    2008-01-01

    We have synthesized a new amphiphilic block oligomer by the enzymatic linking of a fatty acid (lauric acid) to a fructan oligomer (inulin) and tested the functionality of this carbohydrate derivative in foam stabilization. The structure of the modified oligosaccharide was found to be

  6. Nye estimater av organdoser til barn ved datatomografi (CT) utført på 1990-tallet i Norge

    OpenAIRE

    Toft, Benthe

    2013-01-01

    Bakgrunn: Bruk av datatomografi (CT) har økt i Norge de siste ti årene og står nå for 80 % av befolkningsdosen fra medisinsk bruk av stråling. Det er usikkerhet rundt risikoen ved bruk av ioniserende stråling, særlig knyttet til CT av barn og unge. En stor internasjonal studie (EPI-CT-prosjektet) tar sikte på å skaffe økt kunnskap om risiko for leukemi og hjernekreft forbundet med CT-undersøkelser hos barn og unge. Studiens hensikt: Karlegging av organdoser til barn ved CT-undersøkelser p...

  7. Subcortical18F-AV-1451 binding patterns in progressive supranuclear palsy.

    Science.gov (United States)

    Cho, Hanna; Choi, Jae Yong; Hwang, Mi Song; Lee, Seung Ha; Ryu, Young Hoon; Lee, Myung Sik; Lyoo, Chul Hyoung

    2017-01-01

    Accumulation of cortical and subcortical tau pathology is the primary pathological substrate for progressive supranuclear palsy (PSP). 18 F-AV-1451, a radiotracer that binds to the pathological tau protein, may be helpful for in vivo visualization and quantitation of tau pathology in PSP. The objectives of this study were to investigate cortical and subcortical 18 F-AV-1451 binding patterns in patients with PSP. We recruited 14 PSP patients and compared their cortical and subcortical binding patterns in 18 F-AV-1451 positron emission tomography (PET) studies with those of 15 Parkinson's disease (PD) patients and 15 healthy controls. In both the PD and PSP groups, subcortical 18 F-AV-1451 binding did not correlate with the severity of motor dysfunctions, and cortical binding did not differ between the controls and each patient group. However, the PSP patients showed greater 18 F-AV-1451 binding in the putamen, globus pallidus, subthalamic nucleus, and dentate nucleus when compared with the controls, whereas the PD patients showed lower 18 F-AV-1451 binding in the substantia nigra than controls. The PSP and PD patients showed distinct subcortical 18 F-AV-1451 binding patterns reflecting subcortical tau pathology in PSP and reduced nigral neuromelanin in PD. However, there was no correlation with the severity of motor dysfunction, no cortical regions with increased binding in PSP patients, and variable degrees of subcortical binding even in the controls. Therefore, the 18 F-AV-1451 PET may be less than ideal for assessing tau pathology in PSP. Further studies will be required to validate the clinical correlation and to understand the clinical utility of 18 F-AV-1451 PET for PSP patients. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

  8. Validating novel tau PET tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

    Science.gov (United States)

    Marquie, Marta; Normandin, Marc D.; Vanderburg, Charles R.; Costantino, Isabel; Bien, Elizabeth A.; Rycyna, Lisa G.; Klunk, William E.; Mathis, Chester A.; Ikonomovic, Milos D.; Debnath, Manik L.; Vasdev, Neil; Dickerson, Bradford C.; Gomperts, Stephen N.; Growdon, John H.; Johnson, Keith A.; Frosch, Matthew P.; Hyman, Bradley T.; Gomez-Isla, Teresa

    2016-01-01

    Objective To examine region and substrate-specific autoradiographic and in vitro binding patterns of PET tracer [F-18]-AV-1451 (previously known as T807), tailored to allow in vivo detection of paired helical filament tau-containing lesions, and to determine whether there is off-target binding to other amyloid/non-amyloid proteins. Methods We applied [F-18]-AV-1451 phosphor screen autoradiography, [F-18]-AV-1451 nuclear emulsion autoradiography and [H-3]-AV-1451 in vitro binding assays to the study of postmortem samples from patients with a definite pathological diagnosis of Alzheimer’s disease, frontotemporal lobar degeneration-tau, frontotemporal lobar degeneration-TDP-43, progressive supranuclear palsy, corticobasal degeneration, dementia with Lewy bodies, multiple system atrophy, cerebral amyloid angiopathy and elderly controls free of pathology. Results Our data suggest that AV-1451 strongly binds to tau lesions primarily made of paired helical filaments in Alzheimer’s brains e.g. intra and extraneuronal tangles and dystrophic neurites, but does not seem to bind to a significant extent to neuronal and glial inclusions mainly composed of straight tau filaments in non-Alzheimer tauopathy brains or to β-amyloid, α-synuclein or TDP-43-containing lesions. AV-1451 off-target binding to neuromelanin- and melanin-containing cells and, to a lesser extent, to brain hemorrhagic lesions was identified. Interpretation Our data suggest that AV-1451 holds promise as surrogate marker for the detection of brain tau pathology in the form of tangles and paired helical filament-tau-containing neurites in Alzheimer’s brains but also point to its relatively lower affinity for lesions primarily made of straight tau filaments in non-Alzheimer tauopathy cases and to the existence of some AV-1451 off-target binding. These findings provide important insights for interpreting in vivo patterns of [F-18]-AV-1451 retention. PMID:26344059

  9. Celiac ganglia block

    Energy Technology Data Exchange (ETDEWEB)

    Akinci, Devrim [Department of Radiology, Hacettepe University School of Medicine, Sihhiye, 06100 Ankara (Turkey); Akhan, Okan [Department of Radiology, Hacettepe University School of Medicine, Sihhiye, 06100 Ankara (Turkey)]. E-mail: oakhan@hacettepe.edu.tr

    2005-09-01

    Pain occurs frequently in patients with advanced cancers. Tumors originating from upper abdominal viscera such as pancreas, stomach, duodenum, proximal small bowel, liver and biliary tract and from compressing enlarged lymph nodes can cause severe abdominal pain, which do not respond satisfactorily to medical treatment or radiotherapy. Percutaneous celiac ganglia block (CGB) can be performed with high success and low complication rates under imaging guidance to obtain pain relief in patients with upper abdominal malignancies. A significant relationship between pain relief and degree of tumoral celiac ganglia invasion according to CT features was described in the literature. Performing the procedure in the early grades of celiac ganglia invasion on CT can increase the effectiveness of the CGB, which is contrary to World Health Organization criteria stating that CGB must be performed in patients with advanced stage cancer. CGB may also be effectively performed in patients with chronic pancreatitis for pain palliation.

  10. Photovoltaic building blocks

    DEFF Research Database (Denmark)

    Hanberg, Peter Jesper; Jørgensen, Anders Michael

    2014-01-01

    efficiency of about 15% for commercial Silicon solar cells there is still much to gain. DTU Danchip provides research facilities, equipment and expertise for the building blocks that comprises fabricating the efficient solar cell. In order to get more of the sun light into the device we provide thin film......Photovoltaics (PV), better known as solar cells, are now a common day sight on many rooftops in Denmark.The installed capacity of PV systems worldwide is growing exponentially1 and is the third most importantrenewable energy source today. The cost of PV is decreasing fast with ~10%/year but to make...... it directcompetitive with fossil energy sources a further reduction is needed. By increasing the efficiency of the solar cells one gain an advantage through the whole chain of cost. So that per produced Watt of power less material is spent, installation costs are lower, less area is used etc. With an average...

  11. Atomic Basic Blocks

    Science.gov (United States)

    Scheler, Fabian; Mitzlaff, Martin; Schröder-Preikschat, Wolfgang

    Die Entscheidung, einen zeit- bzw. ereignisgesteuerten Ansatz für ein Echtzeitsystem zu verwenden, ist schwierig und sehr weitreichend. Weitreichend vor allem deshalb, weil diese beiden Ansätze mit äußerst unterschiedlichen Kontrollflussabstraktionen verknüpft sind, die eine spätere Migration zum anderen Paradigma sehr schwer oder gar unmöglich machen. Wir schlagen daher die Verwendung einer Zwischendarstellung vor, die unabhängig von der jeweils verwendeten Kontrollflussabstraktion ist. Für diesen Zweck verwenden wir auf Basisblöcken basierende Atomic Basic Blocks (ABB) und bauen darauf ein Werkzeug, den Real-Time Systems Compiler (RTSC) auf, der die Migration zwischen zeit- und ereignisgesteuerten Systemen unterstützt.

  12. Celiac ganglia block

    International Nuclear Information System (INIS)

    Akinci, Devrim; Akhan, Okan

    2005-01-01

    Pain occurs frequently in patients with advanced cancers. Tumors originating from upper abdominal viscera such as pancreas, stomach, duodenum, proximal small bowel, liver and biliary tract and from compressing enlarged lymph nodes can cause severe abdominal pain, which do not respond satisfactorily to medical treatment or radiotherapy. Percutaneous celiac ganglia block (CGB) can be performed with high success and low complication rates under imaging guidance to obtain pain relief in patients with upper abdominal malignancies. A significant relationship between pain relief and degree of tumoral celiac ganglia invasion according to CT features was described in the literature. Performing the procedure in the early grades of celiac ganglia invasion on CT can increase the effectiveness of the CGB, which is contrary to World Health Organization criteria stating that CGB must be performed in patients with advanced stage cancer. CGB may also be effectively performed in patients with chronic pancreatitis for pain palliation

  13. [18F]AV-1451 tau-PET and primary progressive aphasia.

    Science.gov (United States)

    Josephs, Keith A; Martin, Peter R; Botha, Hugo; Schwarz, Christopher G; Duffy, Joseph R; Clark, Heather M; Machulda, Mary M; Graff-Radford, Jonathan; Weigand, Stephen D; Senjem, Matthew L; Utianski, Rene L; Drubach, Daniel A; Boeve, Bradley F; Jones, David T; Knopman, David S; Petersen, Ronald C; Jack, Clifford R; Lowe, Val J; Whitwell, Jennifer L

    2018-02-16

    To assess [ 18 F]AV-1451 tau-PET (positron emission tomography) uptake patterns across the primary progressive aphasia (PPA) variants (logopenic, semantic, and agrammatic), examine regional uptake patterns of [ 18 F]AV-1451 independent of clinical diagnosis, and compare the diagnostic utility of [ 18 F]AV-1451, [ 18 F]-fluorodeoxygluclose (FDG)-PET and MRI (magnetic resonance imaging) to differentiate the PPA variants. We performed statistical parametric mapping of [ 18 F]AV-1451 across 40 PPA patients (logopenic-PPA = 14, semantic-PPA = 13, and agrammatic-PPA = 13) compared to 80 cognitively normal, Pittsburgh compound B-negative controls, age and gender matched 2:1. Principal component analysis of regional [ 18 F]AV-1451 tau-PET standard uptake value ratio was performed to understand underlying patterns of [ 18 F]AV-1451 uptake independent of clinical diagnosis. Penalized multinomial regression analyses were utilized to assess diagnostic utility. Logopenic-PPA showed striking uptake throughout neocortex, particularly temporoparietal, compared to controls, semantic-PPA, and agrammatic-PPA. Semantic-PPA and agrammatic-PPA showed milder patterns of focal [ 18 F]AV-1451 uptake. Semantic-PPA showed elevated uptake (left>right) in anteromedial temporal lobes, compared to controls and agrammatic-PPA. Agrammatic-PPA showed elevated uptake (left>right) throughout prefrontal white matter and in subcortical gray matter structures, compared to controls and semantic-PPA. The principal component analysis of regional [ 18 F]AV-1451 indicated two primary dimensions, a severity dimension that distinguished logopenic-PPA from agrammatic-PPA and semantic-PPA, and a frontal versus temporal contrast that distinguishes agrammatic-PPA and semantic-PPA cases. Diagnostic utility of [ 18 F]AV-1451was superior to MRI and at least equal to FDG-PET. [ 18 F]AV-1451binding characteristics differ across the PPA variants and were excellent at distinguishing between the variants. [ 18

  14. Percepções e sentimentos de adolescentes criados por avós

    OpenAIRE

    Paixão, Flávia Juliana Dourado

    2013-01-01

    Este estudo tem como objetivo conhecer as percepções e os sentimentos de adolescentes criados por avós. Busca-se, especificamente: 1) descrever a percepção dos adolescentes sobre seus avós, seus sentimentos por eles e as relações estabelecidas com os mesmos; 2) descrever como percebem as figuras parentais biológicas, seus sentimentos por eles e suas relações com os mesmos; 3) compreender a experiência dos adolescentes acerca do fato de serem criados pelos avós; e 4) descrever a...

  15. Måleegenskaper ved den norske versjonen av Parental Stress Scales (PSS)

    OpenAIRE

    Kornør, Hege; Richter, Jörg

    2013-01-01

    - Beskrivelse. Parental Stress Scale (PSS) er et spørreskjema med 18 utsagn som foreldre skal besvare for å gi et mål på stressnivå forbundet med det å være foreldre. Instrumentet ble utgitt på engelsk av de amerikanske forskerne Judy O. Berry og Warren H. Jones i 1995. Ane Nærde ved Atferdssenteret står bak den norske oversettelsen. Opplysninger om rettighetshavere foreligger ikke. Tidsbruk og kompetansekrav knyttet til bruk av testen er ukjent. Litteratursøk. Av 51 identifiserte refe...

  16. Evaluering av Brobyggerprosjektet : arbeid overfor unge domfelte menn med somalisk og pakistansk bakgrunn

    OpenAIRE

    Gotaas, Nora; Højdahl, Torunn

    2006-01-01

    Brobyggerprosjektet ved Primærmedisinsk verksted var et 3- årig prosjekt rettet inn mot unge domfelte menn med somalisk og pakistansk bakgrunn. Formålet var å prøve ut virkemidler for å styrke den straffedømtes evne til mestring av egen livssituasjon, og å bygge og utvikle sosiale bånd mellom livet innenfor og livet utenfor fengselsmurene. Evalueringen beskriver og vurderer gjennomføringen av prosjektet. NIBRs del av rapporten er rettet inn mot de organisatoriske sidene v...

  17. Preparation of Waste GFRP Fiber Reinforced Gypsum Block with Water-resistant and Energy Storage Characteristics

    Directory of Open Access Journals (Sweden)

    Zhang Meng-Meng

    2017-01-01

    Full Text Available Gypsum block possesses good performances such as volume stability, lightweight and thermal insulation, is recognized as typical eco-friendly building material. However, its poor water resistance characteristics restrict the application. The semi-hydrated desulphurization gypsum is modified with steel slag, granulated blast-furnace and carbide slag (SGC composite powder as well as waste glass-reinforced plastic (GFRP fiber, aiming at producing water-resistant gypsum block. The proper mass proportioning of the modified gypsum block is obtained: semi-hydrated desulphurization gypsum 75%, SGC 25% and waste GFRP fiber 1.0%. The product is of softening coefficient of 0.84 and thermal flexural strength of 8.6 MPa. Phase change energy storage material (PCM is used to increase the energy saving characteristics of the block. Compared with ordinary gypsum walls, the modified gypsum block with CA-SA exhibits good energy storage property.

  18. A Study of Subseasonal Predictability of the Atmospheric Circulation Low-frequency Modes based on SL-AV forecasts

    Science.gov (United States)

    Kruglova, Ekaterina; Kulikova, Irina; Khan, Valentina; Tischenko, Vladimir

    2017-04-01

    The subseasonal predictability of low-frequency modes and the atmospheric circulation regimes is investigated based on the using of outputs from global Semi-Lagrangian (SL-AV) model of the Hydrometcentre of Russia and Institute of Numerical Mathematics of Russian Academy of Science. Teleconnection indices (AO, WA, EA, NAO, EU, WP, PNA) are used as the quantitative characteristics of low-frequency variability to identify zonal and meridional flow regimes with focus on control distribution of high impact weather patterns in the Northern Eurasia. The predictability of weekly and monthly averaged indices is estimated by the methods of diagnostic verification of forecast and reanalysis data covering the hindcast period, and also with the use of the recommended WMO quantitative criteria. Characteristics of the low frequency variability have been discussed. Particularly, it is revealed that the meridional flow regimes are reproduced by SL-AV for summer season better comparing to winter period. It is shown that the model's deterministic forecast (ensemble mean) skill at week 1 (days 1-7) is noticeably better than that of climatic forecasts. The decrease of skill scores at week 2 (days 8-14) and week 3( days 15-21) is explained by deficiencies in the modeling system and inaccurate initial conditions. It was noticed the slightly improvement of the skill of model at week 4 (days 22-28), when the condition of atmosphere is more determined by the flow of energy from the outside. The reliability of forecasts of monthly (days 1-30) averaged indices is comparable to that at week 1 (days 1-7). Numerical experiments demonstrated that the forecast accuracy can be improved (thus the limit of practical predictability can be extended) through the using of probabilistic approach based on ensemble forecasts. It is shown that the quality of forecasts of the regimes of circulation like blocking is higher, than that of zonal flow.

  19. Computational Modelling of Catalytic Properties and Modified Substrates of Fungal B-N-Acetylhexosaminidases

    Czech Academy of Sciences Publication Activity Database

    Kulik, Natallia; Slámová, Kristýna

    2011-01-01

    Roč. 8, č. 3 (2011), s. 270-280 ISSN 1570-193X R&D Projects: GA ČR(CZ) GAP207/11/0629; GA ČR GD305/09/H008; GA MŠk(CZ) LC06010 Institutional research plan: CEZ:AV0Z50200510; CEZ:AV0Z60870520 Keywords : beta-N-Acetylhexosaminidase * computer modelling * modified substrate Subject RIV: CE - Biochemistry Impact factor: 2.406, year: 2011

  20. Bio-compatibility of ion beam-modified and RGD-grafted polyethylene

    Czech Academy of Sciences Publication Activity Database

    Ročková-Hlaváčková, K.; Švorčík, V.; Bačáková, Lucie; Dvořánková, B.; Heitz, J.; Hnatowicz, Vladimír

    2004-01-01

    Roč. 225, č. 3 (2004), s. 275-282 ISSN 0168-583X R&D Projects: GA AV ČR IAA5011301; GA ČR GA106/03/0514 Grant - others:CZ-AT(CZ) Aktion 2002-7 Institutional research plan: CEZ:AV0Z5011922 Keywords : modified polyethylene * ion beam * RGD grafting Subject RIV: EI - Biotechnology ; Bionics Impact factor: 0.997, year: 2004

  1. Iminodiacetic acid-modified magnetic poly(2-hydroxyethyl methacrylate)-based microspheres for phosphopeptide enrichment

    Czech Academy of Sciences Publication Activity Database

    Novotná, L.; Emmerová, T.; Horák, Daniel; Kučerová, Z.; Tichá, M.

    2010-01-01

    Roč. 1217, č. 51 (2010), s. 8032-8040 ISSN 0021-9673 R&D Projects: GA AV ČR(CZ) KAN401220801; GA ČR GA203/09/0857; GA ČR GAP503/10/0664 Institutional research plan: CEZ:AV0Z40500505 Keywords : IMAC phosphopeptide separation * IDA-modified magnetic microspheres * Porcine pepsin A Subject RIV: EE - Microbiology, Virology Impact factor: 4.194, year: 2010

  2. CLINICAL AND ANGIOGRAPHIC PROFILE OF PATIENTS WITH COMPLETE HEART BLOCK

    Directory of Open Access Journals (Sweden)

    Kavya Pingali

    2017-05-01

    Full Text Available BACKGROUND The angiographic findings and prognosis of patients with Complete Heart Block (CHB remain unclear. Thus, we aimed to study the clinical profile, risk factors, angiographic distribution and in-hospital outcomes of patients with complete heart block. MATERIALS AND METHODS This was a prospective, single-centred study which included 100 patients who came to the emergency department with CHB. Routine blood investigations including serum electrolytes were done. Coronary angiogram was done and lesions were assessed. Temporary pacemaker was implanted followed by permanent pacemakers in required patients, and in-hospital complications were noted down. RESULTS Commonest age group was above 60 years (75%. The patients were predominantly males. Most common presentation was chest pain (60%; there was regional wall motion abnormality in 30% patients. Degenerative complete heart block was seen in 34% patients, diphtheric myocarditis in 15%, hypokalaemic in 15%, dilated cardiomyopathy in 2%. Of total 53 patients had AV block, 14 had bifascicular block, 23 had LBBB, 6 had RBBB, 3 had Mobitz I and 1 had Mobitz II. Inferior wall myocardial infarction (MI was pervasively present in patients. Temporary pacemakers were implanted in 6 patients and permanent pacemakers in 43 patients. In-hospital outcomes constituted of complication like cardiogenic shock (10% and death (26%. The patients who died either had 80% -90% stenosis in RCA, triple vessel disease, ostioproximal LAD occlusion or diphtheric myocarditis. CONCLUSION Complete heart block was majorly associated with advanced age and inferior wall MI, virtually caused by dominant RCA occlusion. The in-hospital mortality was significantly higher in the patients with CHB.

  3. Improved Motion Estimation Using Early Zero-Block Detection

    Directory of Open Access Journals (Sweden)

    Y. Lin

    2008-07-01

    Full Text Available We incorporate the early zero-block detection technique into the UMHexagonS algorithm, which has already been adopted in H.264/AVC JM reference software, to speed up the motion estimation process. A nearly sufficient condition is derived for early zero-block detection. Although the conventional early zero-block detection method can achieve significant improvement in computation reduction, the PSNR loss, to whatever extent, is not negligible especially for high quantization parameter (QP or low bit-rate coding. This paper modifies the UMHexagonS algorithm with the early zero-block detection technique to improve its coding performance. The experimental results reveal that the improved UMHexagonS algorithm greatly reduces computation while maintaining very high coding efficiency.

  4. Nätverksövervakning av trådlösa accesspunkter

    OpenAIRE

    Heino, Felix

    2016-01-01

    Syftet med examensarbetet är att analysera, implementera och utvärdera metoder för nätverksövervakning av trådlös kommunikationsutrustning i företaget Fibras nätverk. I dag sköts driften av cirka 2300 accesspunkter i Västerås stads trådlösa nätverk av Fibra. I nätverket ingår ett antal Wireless LAN Controller (WLC), vars uppgift är att hantera och konfigurera alla accesspunkter. Varje WLC kan hantera upp till 400 accesspunkter och sköter exempelvis autentiseringen av användarna. Dessutom finn...

  5. En utredning av meddelande-orienterade lager för Twingly

    OpenAIRE

    Säll, Robert

    2013-01-01

    Att flera datorer används för att gemensamt lösa problem är inte någonting nytt. Det finns många distribuerade system i bruk och många olika lösningar för hur dessa ska kommunicera med varandra. Vissa använder sig av meddelande-orienterade lager för kommunikation vilket det finns väldigt många implementationer av. RabbitMQ är ett exempel där att kommunikation går genom en (eller ett kluster av) central nod och kommunicerar med hjälp av protokollet Advanced Message Queue Protocol, AMQP. I en h...

  6. Inverkan av alkalisilikareaktion (ASR) på lamelldammars bärförmåga

    OpenAIRE

    Norberg, Sara; Sawasa, Hadeel

    2014-01-01

    Dammar är en viktig konstruktion i Sverige och i världen bland annat för vattenförsörjning, reglering av flöden och elproduktion. En expansion på grund av en alkalisilikareaktion (ASR) i en betongdamm kan leda till många problem. Bland annat kan det uppstå läckage av vatten och problem med öppning och stängning av luckor. Mycket forskning har lagts ner på att ta reda på hur ASR påverkar hållfastheten och bärförmågan hos betong. Detta examensarbete syftar till att genom en litteraturstudie vis...

  7. Neurofibromatosis with vertebral artery A-V fistula and cervical meningocele -a case report-

    International Nuclear Information System (INIS)

    Kim, Yong Joo; Suh, Kyung Jin; Kim, Tae Heon; Kang, Duk Sik; Park, Yeun Mook; Park, June Sik

    1988-01-01

    Arteriovenous fistula is a rare abnormality in patient with neurofibromatosis. A review of English-language literature revealed only 3 reported cases. We report a case of neurofibromatosis with vertebral artery A-V fistula and cervical meningocele

  8. Dimensional reduction for conformal blocks

    Science.gov (United States)

    Hogervorst, Matthijs

    2016-09-01

    We consider the dimensional reduction of a CFT, breaking multiplets of the d-dimensional conformal group SO( d + 1 , 1) up into multiplets of SO( d, 1). This leads to an expansion of d-dimensional conformal blocks in terms of blocks in d - 1 dimensions. In particular, we obtain a formula for 3 d conformal blocks as an infinite sum over 2 F 1 hypergeometric functions with closed-form coefficients.

  9. A general approach to analyse preconditioners two-by-two block matrices

    Czech Academy of Sciences Publication Activity Database

    Axelsson, Owe

    2012-01-01

    Roč. 19, č. 2 (2012), s. 1-20 ISSN 1070-5325 R&D Projects: GA ČR GA105/09/1830 Institutional research plan: CEZ:AV0Z30860518 Keywords : block preconditioning * nonsymmetric matrices * saddle point systems Subject RIV: BA - General Mathematics Impact factor: 1.202, year: 2012 http://www.quosafulltext.com/sc_ddm/sc_ddm.jsp

  10. CdS-containing nano-assemblies of double hydrophilic block copolymers in water

    Czech Academy of Sciences Publication Activity Database

    Uchman, M.; Procházka, K.; Gatsouli, K.; Pispas, S.; Špírková, Milena

    2011-01-01

    Roč. 289, č. 9 (2011), s. 1045-1053 ISSN 0303-402X R&D Projects: GA ČR GCP205/11/J043; GA ČR GAP208/10/0353 Institutional research plan: CEZ:AV0Z40500505 Keywords : double hydrophilic block copolymers * polymer self-assembly * light scattering Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.331, year: 2011

  11. Impact of Ultraviolet-Blocking Plastic Films on Insect Vectors of Virus Diseases Infesting Crisp Lettuce

    OpenAIRE

    Díaz Desani, Beatriz M.; Biurrun, R.; Moreno, Aránzazu; Nebreda, Miguel; Fereres, Alberto

    2006-01-01

    Ultraviolet (UV)-absorbing plastic films are being used as a photoselective barrier to control insect vectors and associated virus diseases in different horticultural crops. A 2-year experiment was carried out in northeastern Spain (Navarra) to evaluate the impact of a UV-blocking film (AD-IR AV) on the population density of insect pests and the spread of insect-transmitted virus diseases associated with head lettuce [Lactuca sativa (L.)]. Results showed that the UV-absorbing plastic film did...

  12. Learning Potentials in Number Blocks

    DEFF Research Database (Denmark)

    Majgaard, Gunver; Misfeldt, Morten; Nielsen, Jacob

    2012-01-01

    . The tool is called Number Blocks and it combines physical interaction, learning, and immediate feedback. Number Blocks supports the children's understanding of place value in the sense that it allows them to experiment with creating large numbers. We found the blocks contributed to the learning process...... in several ways. The blocks combined mathematics and play, and they included and supported children at different academic levels. The auditory representation, especially the enhanced rhythmic effects due to using speech synthesis, and the rhythm helped the children to pronounce large numbers. This creates...

  13. Common blocks for ASQS(12

    Directory of Open Access Journals (Sweden)

    Lorenzo Milazzo

    1997-05-01

    Full Text Available An ASQS(v is a particular Steiner system featuring a set of v vertices and two separate families of blocks, B and G, whose elements have a respective cardinality of 4 and 6. It has the property that any three vertices of X belong either to a B-block or to a G-block. The parameter cb is the number of common blocks in two separate ASQSs, both defined on the same set of vertices X . In this paper it is shown that cb ≤ 29 for any pair of ASQSs(12.

  14. Nettbrettet: Avisbransjens frelser? : En casestudie av nettbrettsatsingen til fire norske mediehus

    OpenAIRE

    Ihme, Henrik Albert

    2012-01-01

    Denne oppgavens formål er å sammenfatte satsingen på nettbrettutgaver i Norge, ved å studere mediehusene VG, Dagbladet, Aftenposten og Dagens Næringsliv. Oppgaven er utformet som en casestudie, og inneholder en kvantitativ undersøkelse av mediehusenes utgaver gjennom en uke, samt dybdeintervjuer med sentrale aktører. Satsingen sees i lys av utviklingen i avisbransjen de siste årene, samt teoretiske perspektiver som remediering og disruptiv innovering. Mediehusenes strategi og ulike forretning...

  15. Kvalitetsutvärdering av biomedicin och närliggande huvudområden

    DEFF Research Database (Denmark)

    Leffler, Hakon; Fex Svenningsen, Åsa; Emgård, Mia

    2014-01-01

    UKÄ:s utvärdering av biomedicinutbildningar visar på en mycket varierad kvalitet. Nio av 21 utbildningar håller toppklass medan mer än hälften bedöms vara bristande. 21 utbildningar inom biomedicin har satts under lupp. Kvaliteten bedöms som vanligt efter en tregradig skala: mycket hög kvalitet, ...

  16. [18F]AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP.

    Science.gov (United States)

    Coakeley, Sarah; Cho, Sang Soo; Koshimori, Yuko; Rusjan, Pablo; Ghadery, Christine; Kim, Jinhee; Lang, Anthony E; Houle, Sylvain; Strafella, Antonio P

    2018-03-01

    This study investigated binding of [ 18 F]AV-1451 to neuromelanin in the substantia nigra of patients with Parkinson's disease (PD) and progressive supranuclear palsy (PSP). [ 18 F]AV-1451 is a positron emission tomography radiotracer designed to bind pathological tau. A post-mortem study using [ 18 F]AV-1451 discovered off-target binding properties to neuromelanin in the substantia nigra. A subsequent clinical study reported a 30% decrease in [ 18 F]AV-1451 binding in the midbrain of PD patients. A total of 12 patients and 10 healthy age-matched controls were recruited. An anatomical MRI and a 90-min PET scan, using [ 18 F]AV-1451, were acquired from all participants. The standardized uptake value ratio (SUVR) from 60 to 90 min post-injection was calculated for the substantia nigra, using the cerebellar cortex as the reference region. The substantia nigra was delineated using automated region of interest software. An independent samples ANOVA and LSD post hoc testing were used to test for differences in [ 18 F]AV-1451 SUVR between groups. Substantia nigra SUVR from 60 to 90 min was significantly greater in HC compared to both PSP and PD groups. Although the PD group had the lowest SUVR, there was no significant difference in substantia nigra uptake between PD and PSP. [ 18 F]AV-1451 may be the first PET radiotracer capable of imaging neurodegeneration of the substantia nigra in parkinsonisms. Further testing must be done in PD and atypical parkinsonian disorders to support this off-target use of [ 18 F]AV-1451.

  17. [F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging.

    Science.gov (United States)

    Marquié, Marta; Siao Tick Chong, Michael; Antón-Fernández, Alejandro; Verwer, Eline E; Sáez-Calveras, Nil; Meltzer, Avery C; Ramanan, Prianca; Amaral, Ana C; Gonzalez, Jose; Normandin, Marc D; Frosch, Matthew P; Gómez-Isla, Teresa

    2017-10-01

    [F-18]-AV-1451, a PET tracer specifically developed to detect brain neurofibrillary tau pathology, has the potential to facilitate accurate diagnosis of Alzheimer's disease (AD), staging of brain tau burden and monitoring disease progression. Recent PET studies show that patients with mild cognitive impairment and AD dementia exhibit significantly higher in vivo [F-18]-AV-1451 retention than cognitively normal controls. Importantly, PET patterns of [F-18]-AV-1451 correlate well with disease severity and seem to match the predicted topographic Braak staging of neurofibrillary tangles (NFTs) in AD, although this awaits confirmation. We studied the correlation of autoradiographic binding patterns of [F-18]-AV-1451 and the stereotypical spatiotemporal pattern of progression of NFTs using legacy postmortem brain samples representing different Braak NFT stages (I-VI). We performed [F-18]-AV-1451 phosphor-screen autoradiography and quantitative tau measurements (stereologically based NFT counts and biochemical analysis of tau pathology) in three brain regions (entorhinal cortex, superior temporal sulcus and visual cortex) in a total of 22 cases: low Braak (I-II, n = 6), intermediate Braak (III-IV, n = 7) and high Braak (V-VI, n = 9). Strong and selective [F-18]-AV-1451 binding was detected in all tangle-containing regions matching precisely the observed pattern of PHF-tau immunostaining across the different Braak stages. As expected, no signal was detected in the white matter or other non-tangle containing regions. Quantification of [F-18]-AV-1451 binding was very significantly correlated with the number of NFTs present in each brain region and with the total tau and phospho-tau content as reported by Western blot and ELISA. [F-18]-AV-1451 is a promising biomarker for in vivo quantification of brain tau burden in AD. Neuroimaging-pathologic studies conducted on postmortem material from individuals imaged while alive are now needed to confirm these observations.

  18. Utilization of Electrocardiographic P-wave Duration for AV Interval Optimization in Dual-Chamber Pacemakers.

    Science.gov (United States)

    Sorajja, Dan; Bhakta, Mayurkumar D; Scott, Luis Rp; Altemose, Gregory T; Srivathsan, Komandoor

    2010-09-05

    Empiric programming of the atrio-ventricular (AV) delay is commonly performed during pacemaker implantation. Transmitral flow assessment by Doppler echocardiography can be used to find the optimal AV delay by Ritter's method, but this cannot easily be performed during pacemaker implantation. We sought to determine a non-invasive surrogate for this assessment. Since electrocardiographic P-wave duration estimates atrial activation time, we hypothesized this measurement may provide a more appropriate basis for programming AV intervals. A total of 19 patients were examined at the time of dual chamber pacemaker implantation, 13 (68%) being male with a mean age of 77. Each patient had the optimal AV interval determined by Ritter's method. The P-wave duration was measured independently on electrocardiograms using MUSE® Cardiology Information System (version 7.1.1). The relationship between P-wave duration and the optimal AV interval was analyzed. The P-wave duration and optimal AV delay were related by a correlation coefficient of 0.815 and a correction factor of 1.26. The mean BMI was 27. The presence of hypertension, atrial fibrillation, and valvular heart disease was 13 (68%), 3 (16%), and 2 (11%) respectively. Mean echocardiographic parameters included an ejection fraction of 58%, left atrial index of 32 ml/m(2), and diastolic dysfunction grade 1 (out of 4). In patients with dual chamber pacemakers in AV sequentially paced mode and normal EF, electrocardiographic P-wave duration correlates to the optimal AV delay by Ritter's method by a factor of 1.26.

  19. Et sosiologisk blikk på mobbing. En teoretisk studie av paradigmet og fenomenet mobbing

    OpenAIRE

    Stemland, Linn

    2007-01-01

    Mobbing er et tema som har fått stadig mer oppmerksomhet i samfunnsdebatten. Det er gjort lite sosiologisk forskning omkring fenomenet mobbing. Forskningsfeltet mobbing er i dag konstruert og dominert av psykologiens begreper og forståelse. I denne oppgaven prøver jeg å nærme meg en sosiologisk forståelse av begrepet og fenomenet mobbing.

  20. Adaptationer av Esaias Tegnérs Frithiofs saga

    DEFF Research Database (Denmark)

    Nordenfors, Ola

    2008-01-01

    Tegnérs versepos över urnordiska myter hade länge ett starkt om den nordiska läsande allmänheten - därtill starkt understött av Bernhard Crusells omtyckta tonsättningar av dikterna. Men också i Tyskland har Frithiofs saga haft en påfallande genomslagskraft. I uppsatsen granskas särskilt tonsättar...

  1. Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast).

    Science.gov (United States)

    Hutchinson, Mark R; Lewis, Susannah S; Coats, Benjamen D; Skyba, David A; Crysdale, Nicole Y; Berkelhammer, Debra L; Brzeski, Anita; Northcutt, Alexis; Vietz, Christine M; Judd, Charles M; Maier, Steven F; Watkins, Linda R; Johnson, Kirk W

    2009-02-01

    Morphine-induced glial proinflammatory responses have been documented to contribute to tolerance to opioid analgesia. Here, we examined whether drugs previously shown to suppress glial proinflammatory responses can alter other clinically relevant opioid effects; namely, withdrawal or acute analgesia. AV411 (ibudilast) and minocycline, drugs with distinct mechanisms of action that result in attenuation of glial proinflammatory responses, each reduced naloxone-precipitated withdrawal. Analysis of brain nuclei associated with opioid withdrawal revealed that morphine altered expression of glial activation markers, cytokines, chemokines, and a neurotrophic factor. AV411 attenuated many of these morphine-induced effects. AV411 also protected against spontaneous withdrawal-induced hyperactivity and weight loss recorded across a 12-day timecourse. Notably, in the spontaneous withdrawal study, AV411 treatment was delayed relative to the start of the morphine regimen so to also test whether AV411 could still be effective in the face of established morphine dependence, which it was. AV411 did not simply attenuate all opioid effects, as co-administering AV411 with morphine or oxycodone caused three-to-five-fold increases in acute analgesic potency, as revealed by leftward shifts in the analgesic dose response curves. Timecourse analyses revealed that plasma morphine levels were not altered by AV411, suggestive that potentiated analgesia was not simply due to prolongation of morphine exposure or increased plasma concentrations. These data support and extend similar potentiation of acute opioid analgesia by minocycline, again providing converging lines of evidence of glial involvement. Hence, suppression of glial proinflammatory responses can significantly reduce opioid withdrawal, while improving analgesia.

  2. Helhetsorienterad utvärdering av kollektivtrafikåtgärder

    DEFF Research Database (Denmark)

    Hiselius, Lena Winslott; Barfod, Michael Bruhn; Leleur, Steen

    Under hösten 2008 och våren 2009 har forskare vid Avd. Trafik och väg vid Lunds Tekniska Högskola, DTU Transport vid Danmarks Tekniska Universitet samt National-ekonomiska institutionen vid Lunds Universitet genomfört ett forskningsprojekt med syfte att studera tillämpningen av en sammansatt...... (helhetsorienterad) analys av kollektiv-trafikåtgärder....

  3. 31 CFR 545.301 - Blocked account; blocked property.

    Science.gov (United States)

    2010-07-01

    ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TALIBAN (AFGHANISTAN) SANCTIONS... name of the Taliban or persons whose property or interests in property are blocked pursuant to § 545.201, or in which the Taliban or persons whose property or interests in property are blocked pursuant...

  4. BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.

    Science.gov (United States)

    Inai, Kei; Burnside, Jessica L; Hoffman, Stanley; Toole, Bryan P; Sugi, Yukiko

    2013-01-01

    Distal outgrowth and maturation of mesenchymalized endocardial cushions are critical morphogenetic events during post-EMT atrioventricular (AV) valvuloseptal morphogenesis. We explored the role of BMP-2 in the regulation of valvulogenic extracellular matrix (ECM) components, versican and hyaluronan (HA), and cell migration during post-EMT AV cushion distal outgrowth/expansion. We observed intense staining of versican and HA in AV cushion mesenchyme from the early cushion expansion stage, Hamburger and Hamilton (HH) stage-17 to the cushion maturation stage, HH stage-29 in the chick. Based on this expression pattern we examined the role of BMP-2 in regulating versican and HA using 3D AV cushion mesenchymal cell (CMC) aggregate cultures on hydrated collagen gels. BMP-2 induced versican expression and HA deposition as well as mRNA expression of versican and Has2 by CMCs in a dose dependent manner. Noggin, an antagonist of BMP, abolished BMP-2-induced versican and HA as well as mRNA expression of versican and Has2. We further examined whether BMP-2-promoted cell migration was associated with expression of versican and HA. BMP-2- promoted cell migration was significantly impaired by treatments with versican siRNA and HA oligomer. In conclusion, we provide evidence that BMP-2 induces expression of versican and HA by AV CMCs and that these ECM components contribute to BMP-2-induced CMC migration, indicating critical roles for BMP-2 in distal outgrowth/expansion of mesenchymalized AV cushions.

  5. BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.

    Directory of Open Access Journals (Sweden)

    Kei Inai

    Full Text Available Distal outgrowth and maturation of mesenchymalized endocardial cushions are critical morphogenetic events during post-EMT atrioventricular (AV valvuloseptal morphogenesis. We explored the role of BMP-2 in the regulation of valvulogenic extracellular matrix (ECM components, versican and hyaluronan (HA, and cell migration during post-EMT AV cushion distal outgrowth/expansion. We observed intense staining of versican and HA in AV cushion mesenchyme from the early cushion expansion stage, Hamburger and Hamilton (HH stage-17 to the cushion maturation stage, HH stage-29 in the chick. Based on this expression pattern we examined the role of BMP-2 in regulating versican and HA using 3D AV cushion mesenchymal cell (CMC aggregate cultures on hydrated collagen gels. BMP-2 induced versican expression and HA deposition as well as mRNA expression of versican and Has2 by CMCs in a dose dependent manner. Noggin, an antagonist of BMP, abolished BMP-2-induced versican and HA as well as mRNA expression of versican and Has2. We further examined whether BMP-2-promoted cell migration was associated with expression of versican and HA. BMP-2- promoted cell migration was significantly impaired by treatments with versican siRNA and HA oligomer. In conclusion, we provide evidence that BMP-2 induces expression of versican and HA by AV CMCs and that these ECM components contribute to BMP-2-induced CMC migration, indicating critical roles for BMP-2 in distal outgrowth/expansion of mesenchymalized AV cushions.

  6. ANALYSIS OF CELL BLOCK VS . CONVENTIONAL SMEAR IN FLUID CYTOLOGY

    Directory of Open Access Journals (Sweden)

    Jyotsna

    2015-09-01

    Full Text Available BACKGROUND: The cytological examination of aspirates of serous effusions is a routinely accepted , simple , safe and minimally invasive technique . Diagnosis in this investigation , especially in malignant effusions , helps in staging , prognosis and management of the patients . AIMS: To assess the utility and sensitivity of cell block method over conventional smear technique in cytodiagnosis of the serous effusions . METHODS: A total of 72 fluid specimens were subjected to simultaneous processing by conventional s mear and cell block technique . Each fluid specimen was divided into two equal parts and results compared for cellularity , cell architecture , cytoplasmic and nuclear features . Cell blocks were prepared using modified cell block technique using alcohol forma lin fixative . RESULTS: The utility of cell block technique in diagnosing malignant effusions is highly significant as compared to the conventional smear technique . Also , the technique using alcohol formalin fixative is simple , safe and these chemicals are routinely used in laboratory . CONCLUSION: Cell block technique is superior to conventional smear technique , especially for malignant effusions . It gives more information about the architectural arrangement and the likely source of primary . More important is that diagnostic material in cell blocks is available for special studies for . I mmunohistochemistry which can further supplement our knowledge about the primary source of metastasis

  7. Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block.

    Science.gov (United States)

    Salomonsson, Stina; Sonesson, Sven-Erik; Ottosson, Lars; Muhallab, Saad; Olsson, Tomas; Sunnerhagen, Maria; Kuchroo, Vijay K; Thorén, Peter; Herlenius, Eric; Wahren-Herlenius, Marie

    2005-01-03

    Congenital heart block develops in fetuses after placental transfer of Ro/SSA autoantibodies from rheumatic mothers. The condition is often fatal and the majority of live-born children require a pacemaker at an early age. The specific antibody that induces the heart block and the mechanism by which it mediates the pathogenic effect have not been elucidated. In this study, we define the cellular mechanism leading to the disease and show that maternal autoantibodies directed to a specific epitope within the leucine zipper amino acid sequence 200-239 (p200) of the Ro52 protein correlate with prolongation of fetal atrioventricular (AV) time and heart block. This finding was further confirmed experimentally in that pups born to rats immunized with p200 peptide developed AV block. p200-specific autoantibodies cloned from patients bound cultured cardiomyocytes and severely affected Ca2+ oscillations, leading to accumulating levels and overload of intracellular Ca2+ levels with subsequent loss of contractility and ultimately apoptosis. These findings suggest that passive transfer of maternal p200 autoantibodies causes congenital heart block by dysregulating Ca2+ homeostasis and inducing death in affected cells.

  8. The psoas compartment block for hip surgery: the past, present, and future

    NARCIS (Netherlands)

    de Leeuw, M.A.; Zuurmond, W.W.A.; Perez, R.S.G.M.

    2011-01-01

    A posterior lumbar plexus block or psoas compartment block (PCB) is an effective locoregional anesthetic technique for analgesia and anesthesia of the entire lower extremity including the hip. Since the first description in the early seventies, this technique has been modified based on advanced

  9. Classical Virasoro irregular conformal block

    Science.gov (United States)

    Rim, Chaiho; Zhang, Hong

    2015-07-01

    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  10. Classical Virasoro irregular conformal block

    Energy Technology Data Exchange (ETDEWEB)

    Rim, Chaiho; Zhang, Hong [Department of Physics and Center for Quantum Spacetime (CQUeST), Sogang University,Seoul 121-742 (Korea, Republic of)

    2015-07-30

    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  11. Four-block beam collimator

    CERN Document Server

    CERN PhotoLab

    1977-01-01

    The photo shows a four-block collimator installed on a control table for positioning the alignment reference marks. Designed for use with the secondary beams, the collimators operated in vacuum conditions. The blocks were made of steel and had a standard length of 1 m. The maximum aperture had a square coss-section of 144 cm2. (See Annual Report 1976.)

  12. OPAL Various Lead Glass Blocks

    CERN Document Server

    These lead glass blocks were part of a CERN detector called OPAL (one of the four experiments at the LEP particle detector). OPAL uses some 12 000 blocks of glass like this to measure particle energies in the electromagnetic calorimeter. This detector measured the energy deposited when electrons and photons were slowed down and stopped.

  13. Writing Blocks and Tacit Knowledge.

    Science.gov (United States)

    Boice, Robert

    1993-01-01

    A review of the literature on writing block looks at two kinds: inability to write in a timely, fluent fashion, and reluctance by academicians to assist others in writing. Obstacles to fluent writing are outlined, four historical trends in treating blocks are discussed, and implications are examined. (MSE)

  14. Block storage subsystem performance analysis

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    You feel that your service is slow because of the storage subsystem? But there are too many abstraction layers between your software and the raw block device for you to debug all this pile... Let's dive on the platters and check out how the block storage sees your I/Os! We can even figure out what those patterns are meaning.

  15. Güneydoğu Marmara'da Algarna ile Karides Avcılığında Av Kompozisyonu ve Hedef Dışı Av.

    Directory of Open Access Journals (Sweden)

    Yusuf Kenan Bayhan

    2015-12-01

    Full Text Available Bir yıl süre ile yürütülen bu çalışma, Kasım 2000 - Ekim 2001 tarihleri arasında Güneydoğu Marmara’da gerçekleştirilmiştir. Çalışmada, algarna ile avcılıkta hedef tür olan derin su pembe karidesi (Parapenaeus longirostris’in ağırlık ve sayısal miktarları ile bunun dışındaki av kompozisyonu, türlerin boy dağılımları ve toplam av içerisindeki sayısal oranları araştırılmıştır. Yapılan çekimler sonucunda, toplam avın sayısal olarak % 64.5’ni hedef tür olan Parapenaeus longirostris, % 35.5’ini hedef dışı av oluşturmuştur. 50 türün bulunduğu hedef dışı avın % 17.16’sını Kemikli balıklar (Osteichthyes, % 8.58’ini Kabuklular (Crustacea-Decapoda, % 4.94’ünü Derisi Dikenliler (Echinodermata, % 2.53’ünü Yumuşakçalar (Mollusca, % 2.14’ünü Cnidaria ve % 0.13’ünü kıkırdaklı balıklar (Chondrichthyes oluşturmuş, toplam av içerisinde Parapenaeus longirostris’in dışında sayısal olarak en çok yakalanan türlerin başında ise Kaya balığı, Mezgit, Kancaağız pisi, Yengeç, Deniz yıldızı ve Deniz hıyarı’nın geldiği belirlenmiştir

  16. A 2:1 AV rhythm: an adverse effect of a long AV delay during DDI pacing and its prevention by the ventricular intrinsic preference algorithm in DDD mode.

    Science.gov (United States)

    Minamiguchi, Hitoshi; Oginosawa, Yasushi; Kohno, Ritsuko; Tamura, Masahito; Takeuchi, Masaaki; Otsuji, Yutaka; Abe, Haruhiko

    2012-07-01

    A 91-year-old woman received a dual-chamber pacemaker for sick sinus syndrome and intermittently abnormal atrioventricular (AV) conduction. The pacemaker was set in DDI mode with a 350-ms AV delay to preserve intrinsic ventricular activity. She complained of palpitation during AV sequential pacing. The electrocardiogram showed a 2:1 AV rhythm from 1:1 ventriculoatrial (VA) conduction during ventricular pacing in DDI mode with a long AV interval. After reprogramming of the pacemaker in DDD mode with a 250-ms AV interval and additional 100-ms prolongation of the AV interval by the ventricular intrinsic preference function, VA conduction disappeared and the patient's symptom were alleviated without increasing unnecessary right ventricular pacing. ©2011, The Authors. Journal compilation ©2011 Wiley Periodicals, Inc.

  17. Differential effect of ganglionic plexi ablation in a patient with neurally mediated syncope and intermittent atrioventricular block.

    Science.gov (United States)

    Fukunaga, Masato; Wichterle, Dan; Peichl, Petr; Aldhoon, Bashar; Čihák, Robert; Kautzner, Josef

    2017-01-01

    In patients with severe neurally mediated syncope (NMS), radiofrequency catheter ablation (RFA) of ganglionic plexi (GP) has been proposed as a new therapeutic approach. Cardio-inhibitory response during NMS is usually related to the sinoatrial (SA) and less frequently to atrioventricular (AV) node. Differential effect of GP ablation on SA and AV node is poorly understood. We report a case of a 35-year-old female with frequent symptomatic episodes of advanced AV block treated by anatomically guided RFA at empirical sites of GPs. After RFA at the septal portion of the right atrium-superior vena cava junction, heart rate accelerated from 62 to 91 beats/min and PR interval prolonged from 213 to 344 ms. Sustained first-degree AV block allowed to observe directly the effects of subsequent RFA on the AV nodal properties. Subsequent RFA at right- and left-sided aspects of the inter-atrial septum had no further effect on heart rate and PR interval. Ablation at the inferior left GP was critical for restoration of normal AV conduction (final PR interval of 187 ms). No bradycardia episodes were observed by implantable loop recorder during the follow-up of 10 months and the patient was symptomatically improved. This is the first clinical case showing the differential effect of GP ablation on SA and AV nodal function, and critical importance of targeting the GP at the postero-inferior left atrium. The successful procedure corroborates clinical utility of ablation treatment instead of pacemaker implantation in selected patients with cardio-inhibitory NMS. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  18. Integrated rate-dependent and dual pathway AV nodal functions: principles and assessment framework.

    Science.gov (United States)

    Billette, Jacques; Tadros, Rafik

    2014-01-15

    The atrioventricular (AV) node conducts slowly and has a long refractory period. These features sustain the filtering of atrial impulses and hence are often modulated to optimize ventricular rate during supraventricular tachyarrhythmias. The AV node is also the site of a clinically common reentrant arrhythmia. Its function is assessed for a variety of purposes from its responses to a premature protocol (S1S2, test beats introduced at different cycle lengths) repeatedly performed at different basic rates and/or to an incremental pacing protocol (increasingly faster rates). Puzzlingly, resulting data and interpretation differ with protocols as well as with chosen recovery and refractory indexes, and are further complicated by the presence of built-in fast and slow pathways. This problem applies to endocavitary investigations of arrhythmias as well as to many experimental functional studies. This review supports an integrated framework of rate-dependent and dual pathway AV nodal function that can account for these puzzling characteristics. The framework was established from AV nodal responses to S1S2S3 protocols that, compared with standard S1S2 protocols, allow for an orderly quantitative dissociation of the different factors involved in changes in AV nodal conduction and refractory indexes under rate-dependent and dual pathway function. Although largely based on data from experimental studies, the proposed framework may well apply to the human AV node. In conclusion, the rate-dependent and dual pathway properties of the AV node can be integrated within a common functional framework the contribution of which to individual responses can be quantitatively determined with properly designed protocols and analytic tools.

  19. A Practical ECG Criterion to Unmask Left Accessory AV Connections in Patients With Subtle Preexcitation.

    Science.gov (United States)

    Thompson, J Jenkins; Shah, Jignesh; Charnigo, Richard; Tackett, Andrea; Darrat, Yousef H; Bailey, Alison; Delisle, Brian; Kakavand, Bahram; DI Biase, Luigi; Natale, Andrea; Morales, Gustavo; Elayi, Claude S

    2015-05-20

    Accessory AV-connections capable of antegrade conduction need to be recognized because of the potential for life-threatening arrhythmias. However, the preexcited ECG pattern may be subtle, especially among left-sided AV-connections. We explored whether additional ECG criteria might help identify left-sided AV-connections. We analyzed 156 patients who underwent an electrophysiology study (EPS) and ablation for paroxysmal supraventricular tachycardias (PSVT). Patients were divided into 2 groups: those with left-sided AV-connections (Group 1) and all other PSVT (Group 2). Various ECG parameters were compared before and after ablation in both groups. The EPS identified left-sided AV-connections among 43 patients (Group 1) and excluded it among 113 (Group 2). Baseline ECG in Group 1 demonstrated obvious preexcitation among 24/43 patients (55.8%), the remaining 19/43 missing obvious preexcitation. R/S ratio > 0.5 in V1 was noted in 38/43 (88.4%) patients in Group 1 before ablation (median 1.00; IQR 0.58-2.20), including 16/19 (84.2%) patients lacking obvious left-sided AVconnections. Conversely, only 10/113 (8.8%) patients in Group 2 had R/S ratios in V1 ≥ 0.5 (0.20; 0.10-0.31), P AV-connections (sensitivity 93.0%). The negative predictive value of this combined criterion was 103/106 (97.2%). In symptomatic patients, combining the R/S ratio (≥ 0.5) in lead V1 with the classic preexcitation pattern on ECG markedly improved the sensitivity to diagnose left-sided AV-connections. This ratio may be particularly useful among patients lacking obvious preexcitation. © 2015 Wiley Periodicals, Inc.

  20. A novel curve fitting method for AV optimisation of biventricular pacemakers.

    Science.gov (United States)

    Dehbi, Hakim-Moulay; Jones, Siana; Sohaib, S M Afzal; Finegold, Judith A; Siggers, Jennifer H; Stegemann, Berthold; Whinnett, Zachary I; Francis, Darrel P

    2015-09-01

    In this study, we designed and tested a new algorithm, which we call the 'restricted parabola', to identify the optimum atrioventricular (AV) delay in patients with biventricular pacemakers. This algorithm automatically restricts the hemodynamic data used for curve fitting to the parabolic zone in order to avoid inadvertently selecting an AV optimum that is too long.We used R, a programming language and software environment for statistical computing, to create an algorithm which applies multiple different cut-offs to partition curve fitting of a dataset into a parabolic and a plateau region and then selects the best cut-off using a least squares method. In 82 patients, AV delay was adjusted and beat-to-beat systolic blood pressure (SBP) was measured non-invasively using our multiple-repetition protocol. The novel algorithm was compared to fitting a parabola across the whole dataset to identify how many patients had a plateau region, and whether a higher hemodynamic response was achieved with one method.In 9/82 patients, the restricted parabola algorithm detected that the pattern was not parabolic at longer AV delays. For these patients, the optimal AV delay predicted by the restricted parabola algorithm increased SBP by 1.36 mmHg above that predicted by the conventional parabolic algorithm (95% confidence interval: 0.65 to 2.07 mmHg, p-value = 0.002).AV optima selected using our novel restricted parabola algorithm give a greater improvement in acute hemodynamics than fitting a parabola across all tested AV delays. Such an algorithm may assist the development of automated methods for biventricular pacemaker optimisation.

  1. Nye estimater av organdoser til barn ved datatomografi (CT) utført på 1990-tallet i Norge

    OpenAIRE

    Toft, Benthe

    2013-01-01

    Masteroppgave i Folkehelsevitenskap ved Institutt for plante- og miljøvitenskap. 30 studiepoeng. Bakgrunn: Bruk av datatomografi (CT) har økt i Norge de siste ti årene og står nå for 80 % av befolkningsdosen fra medisinsk bruk av stråling. Det er usikkerhet rundt risikoen ved bruk av ioniserende stråling, særlig knyttet til CT av barn og unge. En stor internasjonal studie (EPI-CT-prosjektet) tar sikte på å skaffe økt kunnskap om risiko for leukemi og hjernekreft forbundet med CT-undersøkel...

  2. Criminal Justice Systems. Block I: Law Enforcement. Block II: The Courts. Block III: Corrections. Block IV: Community Relations. Block V: Proficiency Skills. Block VI: Criminalistics. Student Guide.

    Science.gov (United States)

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

    This student guide together with an instructor guide comprise a set of curriculum materials on the criminal justice system. The student guide contains self-contained instructional material that students can study at their own pace most of the time. Six major subject areas or blocks, which are further broken down into several units, with some units…

  3. Criminal Justice Systems. Block I: Law Enforcement. Block II: The Courts. Block III: Corrections. Block IV: Community Relations. Block V: Proficiency Skills. Block VI: Criminalistics. Instructor Guide.

    Science.gov (United States)

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

    This instructor guide together with a student guide comprise a set of curriculum materials on the criminal justice system. The instructor guide is a resource for planning and managing individualized, competency-based instruction in six major subject areas or blocks, which are further broken down into several units with some units having several…

  4. AV interval optimization using pressure volume loops in dual chamber pacemaker patients with maintained systolic left ventricular function.

    Science.gov (United States)

    Eberhardt, Frank; Hanke, Thorsten; Fitschen, Joern; Heringlake, Matthias; Bode, Frank; Schunkert, Heribert; Wiegand, Uwe K H

    2012-08-01

    Atrioventricular (AV) interval optimization is often deemed too time-consuming in dual-chamber pacemaker patients with maintained LV function. Thus the majority of patients are left at their default AV interval. To quantify the magnitude of hemodynamic improvement following AV interval optimization in chronically paced dual chamber pacemaker patients. A pressure volume catheter was placed in the left ventricle of 19 patients with chronic dual chamber pacing and an ejection fraction >45 % undergoing elective coronary angiography. AV interval was varied in 10 ms steps from 80 to 300 ms, and pressure volume loops were recorded during breath hold. The average optimal AV interval was 152 ± 39 ms compared to 155 ± 8 ms for the average default AV interval (range 100-240 ms). The average improvement in stroke work following AV interval optimization was 935 ± 760 mmHg/ml (range 0-2,908; p AV interval changes the average stroke work by 207 ± 162 mmHg/ml. AV interval optimization also leads to improved systolic dyssynchrony indices (17.7 ± 7.0 vs. 19.4 ± 7.1 %; p = 0.01). The overall hemodynamic effect of AV interval optimization in patients with maintained LV function is in the same range as for patients undergoing cardiac resynchronization therapy for several parameters. The positive effect of AV interval optimization also applies to patients who have been chronically paced for years.

  5. Den blivande förskollärarens formering. En studie av verksamhetsförlagda handledningssamtal, argumentationstraditioner och metaforik

    Directory of Open Access Journals (Sweden)

    Marie-Louise Hjort

    2014-06-01

    Full Text Available I denna studie analyserar vi hur erfarna förskollärare i rollen som handledare introducerar förskollärarstudenter i professionen. Studien genomförs mot bakgrund av ett delvis nytt uppdrag som förskolan fått under senare år, som bland annat yttrar sig i att förskolan nu är en del av utbildningssystemet. Med utgångspunkt i det teoretiska begreppet argumentationstraditioner och genom att analysera metaforiken i deltagarnas resonerande, studeras hur erfarna och blivande förskollärare navigerar spänningar centrala för professionen. Deltagarnas betoning av vissa argumentationstraditioner och användningen av viss metaforik diskuteras i termer av vad de implicerar för utvecklingen av de barn som deltar i en förskoleverksamhet som formas av dessa.

  6. Kjøring med mistanke om påvirkning av andre rusmidler enn alkohol

    Directory of Open Access Journals (Sweden)

    Asbjørg S. Christophersen

    2009-10-01

    Full Text Available  SAMMENDRAGStatens rettstoksikologiske institutt har i løpet av de siste år registrert en stor økning av prøver fra bilføreremistenkt for kjøring under påvirkning av andre rusmidler enn alkohol. Antall positive saker økte 42% fra1994 til 1995. De hyppigste påviste stoffer er tetrahydrocannabinol, amfetamin, benzodiazepiner og opiater(morfin/kodein. Bruk av tyngre narkotiske stoffer har blitt mer vanlig i trafikksammenheng og antall positivetilfeller har økt betydelig mer enn totalt antall saker. Fra 1994 til 1995 økte antall positive amfetaminprøvermed 75% (fra 533 til 937 og antall positive prøver som følge av heroininntak økte med 87% (fra 92 til 172.Bruk av flere stoffer samtidig er vanlig, over 60 % av sakene i 1995 var positive på mer enn ett stoff, alkoholikke medregnet. De fleste tilfeller var representert av menn i alderen 25-32 år (37%. Kvinner var representerti ca. 11% av sakene.Christophersen AS, Skurtveit S, Mørland J. Drivers suspected to drive under the influence of drugs otherthan alcohol. Nor J Epidemiol 1996; 6 (1: 45-48.ENGLISH SUMMARYThe National Institute of Forensic Toxicology has registered a large increase in the number of samples fromdrivers suspected to drive under influence of drugs other than alcohol. The number of drug positive casesincreased 42% from 1994 to 1995. The most frequent drugs detected are tetrahydrocannabinol, amphetamine,benzodiazepines and opiates (morphine/codeine. The frequency of hard narcotic drug use has increased morethan the total number of cases. From 1994 to 1995, the number of amphetamine positive samples increased75% (from 533 to 937 and the number of samples positive due to heroin use (detection of the metabolite 6-monoacetylmorphine in urine increased 87%. Multi-drug use is common and more than one drug wasdetected in more than 60% of the cases from 1995, alcohol not included. Most of the cases were representedby men 25-32 years old (37%. Women were represented in about

  7. sugE: A gene involved in tributyltin (TBT) resistance of Aeromonas molluscorum Av27.

    Science.gov (United States)

    Cruz, Andreia; Micaelo, Nuno; Félix, Vitor; Song, Jun-Young; Kitamura, Shin-Ichi; Suzuki, Satoru; Mendo, Sónia

    2013-01-01

    The mechanism of bacterial resistance to tributyltin (TBT) is still unclear. The results herein presented contribute to clarify that mechanism in the TBT-resistant bacterium Aeromonas molluscorum Av27. We have identified and cloned a new gene that is involved in TBT resistance in this strain. The gene is highly homologous (84%) to the Aeromonas hydrophila-sugE gene belonging to the small multidrug resistance gene family (SMR), which includes genes involved in the transport of lipophilic drugs. In Av27, expression of the Av27-sugE was observed at the early logarithmic growth phase in the presence of a high TBT concentration (500 μM), thus suggesting the contribution of this gene for TBT resistance. E. coli cells transformed with Av27-sugE become resistant to ethidium bromide (EtBr), chloramphenicol (CP) and tetracycline (TE), besides TBT. According to the Moriguchi logP (miLogP) values, EtBr, CP and TE have similar properties and are substrates for the sugE-efflux system. Despite the different miLogP of TBT, E. coli cells transformed with Av27-sugE become resistant to this compound. So it seems that TBT is also a substrate for the SugE protein. The modelling studies performed also support this hypothesis. The data herein presented clearly indicate that sugE is involved in TBT resistance of this bacterium.

  8. Context-Aware UPnP-AV Services for Adaptive Home Multimedia Systems

    Directory of Open Access Journals (Sweden)

    Roland Tusch

    2008-01-01

    Full Text Available One possibility to provide mobile multimedia in domestic multimedia systems is the use of Universal Plug and Play Audio Visual (UPnP-AV devices. In a standard UPnP-AV scenario, multimedia content provided by a Media Server device is streamed to Media Renderer devices by the initiation of a Control Point. However, there is no provisioning of context-aware multimedia content customization. This paper presents an enhancement of standard UPnP-AV services for home multimedia environments regarding context awareness. It comes up with context profile definitions, shows how this context information can be queried from the Media Renderers, and illustrates how a Control Point can use this information to tailor a media stream from the Media Server to one or more Media Renderers. Moreover, since a standard Control Point implementation only queries one Media Server at a time, there is no global view on the content of all Media Servers in the UPnP-AV network. This paper also presents an approach of multimedia content integration on the Media Server side that provides fast search for content on the network. Finally, a number of performance measurements show the overhead costs of our enhancements to UPnP-AV in order to achieve the benefits.

  9. Block by Block: Civic Action in the Battle of Baghdad

    Science.gov (United States)

    2007-11-01

    bedding, and latrine facilities. Additionally, provide milk , baby formula, diapers, 7 Bogart: Block by Block and infant/family care items such as...viable agricultural businesses. The cattle are a cross breed of a “regular” Iraqi cow and a water buffalo. Chicken farms are mostly egg farms, and...a problem. Contractors did not want to work for fear of being shot or kid - napped. For example, four contractors were shot over the duration of

  10. Harmony of spinning conformal blocks

    Energy Technology Data Exchange (ETDEWEB)

    Schomerus, Volker [DESY Hamburg, Theory Group,Notkestraße 85, 22607 Hamburg (Germany); Sobko, Evgeny [Nordita and Stockholm University,Roslagstullsbacken 23, SE-106 91 Stockholm (Sweden); Isachenkov, Mikhail [Department of Particle Physics and Astrophysics, Weizmann Institute of Science,Rehovot 7610001 (Israel)

    2017-03-15

    Conformal blocks for correlation functions of tensor operators play an increasingly important role for the conformal bootstrap programme. We develop a universal approach to such spinning blocks through the harmonic analysis of certain bundles over a coset of the conformal group. The resulting Casimir equations are given by a matrix version of the Calogero-Sutherland Hamiltonian that describes the scattering of interacting spinning particles in a 1-dimensional external potential. The approach is illustrated in several examples including fermionic seed blocks in 3D CFT where they take a very simple form.

  11. Harmony of spinning conformal blocks

    Energy Technology Data Exchange (ETDEWEB)

    Schomerus, Volker [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Sobko, Evgeny [Stockholm Univ. (Sweden); Nordita, Stockholm (Sweden); Isachenkov, Mikhail [Weizmann Institute of Science, Rehovoth (Israel). Dept. of Particle Physics and Astrophysics

    2016-12-07

    Conformal blocks for correlation functions of tensor operators play an increasingly important role for the conformal bootstrap programme. We develop a universal approach to such spinning blocks through the harmonic analysis of certain bundles over a coset of the conformal group. The resulting Casimir equations are given by a matrix version of the Calogero-Sutherland Hamiltonian that describes the scattering of interacting spinning particles in a 1-dimensional external potential. The approach is illustrated in several examples including fermionic seed blocks in 3D CFT where they take a very simple form.

  12. Composite materials based on modified epoxy resin and carbon fiber

    OpenAIRE

    Gonçalez, Viviane; Barcia, Fabio L.; Soares, Bluma G.

    2006-01-01

    Epoxy resin networks have been modified with block copolymer of polybutadiene and bisphenol A diglycidyl ether (DGEBA)-based on epoxy resin. The epoxy resin modified with carboxyl-terminated polybutadiene presented improved impact resistance and outstanding mechanical performance in terms of flexural and tensile properties because of the presence of rubber particles homogeneously dispersed inside the epoxy matrix. This modified system also resulted in an improvement of mechanical properties o...

  13. Handelsbankens användande av CRM -Är det lönsamt?

    OpenAIRE

    Salman Kanbar, Ahmad

    2012-01-01

    Frågeställning: På vilket sätt används CRM av Handelsbanken och hur påverkar det bankens lönsamhet? Syfte: Syftet med detta arbete är att kunna öka kunskapen om hur Handelsbanken tillämpar CRM och för att undersöka om användandet av CRM i bankens verksamhet är lönsamt eller inte. Metod: För att svara på studiens syfte blev en intervju utförd med Handelsbanken. Ännu en anledning till varför en intervju gjordes var på grund av att det var nödvändigt för att få det primärdata som behövdes och fö...

  14. Miljöanalys av arbetsmoment i vägprojekt

    OpenAIRE

    Sahlin, Jonathan; Jakobsson, Mattias

    2017-01-01

    Klimatpåverkan och energiförbrukning är ett av de stora miljöproblemen runt om i världen idag. Sedan den industriella revolutionens start har mängden utsläpp av bland annat koldioxid ökat exponentiellt med årens lopp och skapat obalans i klimatet, inte minst på grund av restprodukter och skadliga ämnen som används inom bland annat byggindustrin. Syftet med denna studie är att ta reda på vilka arbetsmoment som har störst påverkan på miljön för att sedan, om möjligt, ta fram förslag på hur det ...

  15. FastVDO enhancements of the AV1 codec and comparison to HEVC and JVET codecs

    Science.gov (United States)

    Topiwala, Pankaj; Dai, Wei; Krishnan, Madhu

    2017-09-01

    This paper describes a study to investigate possible ways to improve the AV1 codec, in several directions, most particularly in the context of 10-bit HDR video content, and 8/10 bit image content. Applications to SDR video, and 360 content are discussed elsewhere. For HDR content, a data adaptive grading technique in conjunction with the AV1 codec is studied. For image content, lapped biorthogonal transforms for (near) lossless compression is studied. For scalability-type applications, we introduce advanced resampling filters which outperform current ones. It is asserted that useful improvements are possible in each of these categories. In particular, substantial value is offered in the coding of HDR content, very competitive with HEVC HDR10, in a coding framework offering backwards compatibility with SDR. We also provide a rudimentary comparison of AV1 to the standard HEVC as well as the developing JVET codecs.

  16. Forholdet mellom stat og kommune i styring av norsk utdanningspolitikk 1970 - 2008

    Directory of Open Access Journals (Sweden)

    Øystein Engeland

    2009-06-01

    Full Text Available Denne artikkelen er skrevet ut fra en antakelse om at norsk utdanningsforvaltning etter 1990 illustrerer forsøk på å styrke den statlige forvaltning innen et desentralisert system. Ikke minst er dette tydelig ved at nasjonal styring av utdanning særlig etter århundreskiftet har økt på bekostning av det lokale selvstyret. I forhold til maktfordelingen mellom staten og kommunene er vi nå nærmest tilbake til situasjonen før den politiske desentraliseringsbølgen startet mot slutten av 1970-tallet. Det nasjonale nivået er i ferd med å etablere et styringsgrep på skolesiden som er så omfattende at det mangler sidestykke i moderne tid. Det nye er at dette skjer innen et system hvor inntektssystemet (1986 gir kommunene ansvar for undervisningen, og hvor statens mulighet til å bruke økonomiske styringsmidler er redusert.

  17. Left bundle-branch block

    DEFF Research Database (Denmark)

    Risum, Niels; Strauss, David; Sogaard, Peter

    2013-01-01

    The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a fundamental understanding of physiology have recently...

  18. The wild tapered block bootstrap

    DEFF Research Database (Denmark)

    Hounyo, Ulrich

    -based method in terms of asymptotic accuracy of variance estimation and distribution approximation. For stationary time series, the asymptotic validity, and the favorable bias properties of the new bootstrap method are shown in two important cases: smooth functions of means, and M-estimators. The first......-order asymptotic validity of the tapered block bootstrap as well as the wild tapered block bootstrap approximation to the actual distribution of the sample mean is also established when data are assumed to satisfy a near epoch dependent condition. The consistency of the bootstrap variance estimator for the sample......In this paper, a new resampling procedure, called the wild tapered block bootstrap, is introduced as a means of calculating standard errors of estimators and constructing confidence regions for parameters based on dependent heterogeneous data. The method consists in tapering each overlapping block...

  19. Recursion Relations for Conformal Blocks

    CERN Document Server

    Penedones, João; Yamazaki, Masahito

    2016-09-12

    In the context of conformal field theories in general space-time dimension, we find all the possible singularities of the conformal blocks as functions of the scaling dimension $\\Delta$ of the exchanged operator. In particular, we argue, using representation theory of parabolic Verma modules, that in odd spacetime dimension the singularities are only simple poles. We discuss how to use this information to write recursion relations that determine the conformal blocks. We first recover the recursion relation introduced in 1307.6856 for conformal blocks of external scalar operators. We then generalize this recursion relation for the conformal blocks associated to the four point function of three scalar and one vector operator. Finally we specialize to the case in which the vector operator is a conserved current.

  20. Defying gravity using Jenga™ blocks

    Science.gov (United States)

    Tan, Yin-Soo; Yap, Kueh-Chin

    2007-11-01

    This paper describes how Jenga™ blocks can be used to demonstrate the physics of an overhanging tower that appears to defy gravity. We also propose ideas for how this demonstration can be adapted for the A-level physics curriculum.

  1. AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies.

    Science.gov (United States)

    Kantarci, Kejal; Lowe, Val J; Boeve, Bradley F; Senjem, Matthew L; Tosakulwong, Nikki; Lesnick, Timothy G; Spychalla, Anthony J; Gunter, Jeffrey L; Fields, Julie A; Graff-Radford, Jonathan; Ferman, Tanis J; Jones, David T; Murray, Melissa E; Knopman, David S; Jack, Clifford R; Petersen, Ronald C

    2017-01-01

    Patients with probable dementia with Lewy bodies (DLB) often have Alzheimer's disease (AD)-related pathology. Our objective was to determine the pattern of positron emission tomography (PET) tau tracer AV-1451 uptake in patients with probable DLB, compared to AD, and its relationship to β-amyloid deposition on PET. Consecutive patients with clinically probable DLB (n = 19) from the Mayo Clinic Alzheimer's Disease Research Center underwent magnetic resonance imaging, AV-1451, and Pittsburgh compound-B (PiB) PET examinations. Age- and sex-matched groups of AD dementia (n = 19) patients and clinically normal controls (n = 95) from an epidemiological cohort served as a comparison groups. Atlas- and voxel-based analyses were performed. The AD dementia group had significantly higher AV-1451 uptake than the probable DLB group, and medial temporal uptake completely distinguished AD dementia from probable DLB. Patients with probable DLB had greater AV-1451 uptake in the posterior temporoparietal and occipital cortex compared to clinically normal controls, and in probable DLB, the uptake in these regions correlated with global cortical PiB uptake (Spearman rho = 0.63; p = 0.006). Medial temporal lobe AV-1451 uptake distinguishes AD dementia from probable DLB, which may be useful for differential diagnosis. Elevated posterior temporoparietal and occipital AV-1451 uptake in probable DLB and its association with global cortical PiB uptake suggest an atypical pattern of tau deposition in DLB. ANN NEUROL 2017;81:58-67. © 2016 The Authors. Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.

  2. Multinational evaluation of the interpretability of the iterative method of optimisation of AV delay for CRT.

    Science.gov (United States)

    Raphael, Claire E; Kyriacou, Andreas; Jones, Siana; Pabari, Punam; Cole, Graham; Baruah, Resham; Hughes, Alun D; Francis, Darrel P

    2013-09-20

    AV delay optimisation of biventricular pacing devices (cardiac resynchronisation therapy, CRT) is performed in trials and recommended by current guidelines. The Doppler echocardiographic iterative method is the most commonly recommended. Yet whether it can be executed reliably has never been tested formally. 36 multinational specialists, familiar with using the echocardiographic iterative method of CRT optimisation, were shown 20-40 sets of transmitral Doppler traces at 6-8 AV settings and asked to select the optimal AV delay. Unknown to the specialists, some Doppler datasets appeared in duplicate, allowing assessment of both inter and intra-specialist interpretation. On the Kappa scale of agreement (1 = perfect agreement, 0 = chance alone), the agreement regarding optimal AV delay between specialists was poor (kappa=0.12 ± 0.08). More importantly, agreement of specialists with themselves (i.e. viewing identical sets of traces, twice) was also poor, with Kappa=0.23 ± 0.07 and mean absolute difference in optimum AV delay of 83 ms between first and second viewing of the same traces. Iterative AV optimisation is not executed reliably by experts, even in an artificially simplified context where biological variability and variation in image acquisition are eliminated by use of identical traces. This cannot be blamed on insufficient skills of some experts or discordant methods of selecting the optimum, because operators also showed poor agreement with themselves when assessing the same trace. Instead, guidelines should retract any recommendation for this algorithm. Guideline-development processes might usefully begin with a rudimentary check on proposed algorithms, to establish at least minimal credibility. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  3. The parsec-scale relationship between ICO and AV in local molecular clouds

    Science.gov (United States)

    Lee, Cheoljong; Leroy, Adam K.; Bolatto, Alberto D.; Glover, Simon C. O.; Indebetouw, Remy; Sandstrom, Karin; Schruba, Andreas

    2018-03-01

    We measure the parsec-scale relationship between integrated CO intensity (ICO) and visual extinction (AV) in 24 local molecular clouds using maps of CO emission and dust optical depth from Planck. This relationship informs our understanding of CO emission across environments, but clean Milky Way measurements remain scarce. We find uniform ICO for a given AV, with the results bracketed by previous studies of the Pipe and Perseus clouds. Our measured ICO-AV relation broadly agrees with the standard Galactic CO-to-H2 conversion factor, the relation found for the Magellanic clouds at coarser resolution, and numerical simulations by Glover & Clark (2016). This supports the idea that CO emission primarily depends on shielding, which protects molecules from dissociating radiation. Evidence for CO saturation at high AV and a threshold for CO emission at low AV varies remains uncertain due to insufficient resolution and ambiguities in background subtraction. Resolution of order 0.1 pc may be required to measure these features. We use this ICO-AV relation to predict how the CO-to-H2 conversion factor (XCO) would change if the Solar Neighbourhood clouds had different dust-to-gas ratio (metallicity). The calculations highlight the need for improved observations of the CO emission threshold and H I shielding layer depth. They are also sensitive to the shape of the column density distribution. Because local clouds collectively show a self-similar distribution, we predict a shallow metallicity dependence for XCO down to a few tenths of solar metallicity. However, our calculations also imply dramatic variations in cloud-to-cloud XCO at subsolar metallicity.

  4. Investigation of the microtructure of platinum-modified aluminide coatings

    Czech Academy of Sciences Publication Activity Database

    Pedraza, F.; Kennedy, A.D.; Kopeček, Jaromír; Moretto, P.

    2007-01-01

    Roč. 200, - (2007), s. 4032-4039 ISSN 0257-8972 Grant - others:Marie Curie Fellowship (ORDICO)(XE) G4TR-CT-2000-0042 and G4RD-CT-2000-00319 Institutional research plan: CEZ:AV0Z10100520 Keywords : single crystal nickel superalloy * out-of pack platinum-modified aluminide coating * single phase Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.678, year: 2007

  5. Vegetasjonskartlegging av Muddvær, Vegaøyan verdensarv, Vega kommune

    OpenAIRE

    Bär, Annette; Carlsen, Thomas

    2009-01-01

    Muddværet ble vegetasjonskartlagt for å få oversikt over de botaniske verdiene. Vegetasjonstyper etter Fremstad (1997) er framstilt på kart og rapporten inneholder i tillegg en artsliste over registrerte planter. Kartleggingen skal brukes som grunnlag for en senere utarbeiding av en skjøtselsplan for området og ses i sammenheng med tidligere kartlegginger og utarbeiding av skjøtselsplaner for Vegaøyan verdensarvområde (bl.a. Hatten m.fl. 2007; Hatten & Carlsen 2007a,b).

  6. Fromleik i Black Supper, Piss Christ og Crucifixion, tre fotografi av Andres Serrano

    OpenAIRE

    Vinje, Lilly

    2006-01-01

    Oppgåva skal omhandla tre utvalgte foto av fotografen Andres Serrano, ein amerikanar født i 1950. Enkeltbileta det er snakk om er Black Supper (1990), Piss Christ og Crucifixion (begge 1987). Dei er laga ved at kitschfigurar er nedsenka i gjennomsiktige behaldarar fyllte av kroppsvæsker og vatn; vatn i Black Supper, urin i Piss Christ og blod i Crucifixion. Henholdsvis framstiller dei Nattverden, Jesus på krossen og Krossfestinga (tre figurar). Serrano befinn seg med desse innanfor religiøs k...

  7. Forensisk analys av volatilt minne från operativsystemet OS X

    OpenAIRE

    Ogeskär, Tobias

    2014-01-01

    Behovet av att analysera volatilt minne från Macintosh-datorer med OS X har blivit allt mer betydelsefull på grund av att deras datorer blivit allt populärare och att volatil minnesanalysering blivit en allt viktigare del i en IT-forensikers arbete. Anledningen till att volatil minnesanalysering blivit allt viktigare är för att det går att finna viktig information som inte finns lagrad permanent på datorns interna hårddisk. Problemet som låg till grunden för det här examensarbetet var att det...

  8. Mellom risiko og kontroll - en studie av eksplisitte modelleringsformer i norsk grunnskolelærerutdanning

    Directory of Open Access Journals (Sweden)

    Fride Lindstøl

    2017-12-01

    Full Text Available Å være lærerutdanner skiller seg fra andre stillinger innenfor høyere utdanning: Lærerutdanneren underviser både i fagstoff og i hvordan studentene kan lære bort og adaptere fagstoffet i klasserommet. Det at lærerutdanneren underviser i det å undervise, har implikasjoner for hvordan undervisningen planlegges, gjennomføres og analyseres i lærerutdanningen – undervisningens form blir en del av budskapet. Lærerutdannerens arbeid handler derfor om å utforme, velge og sette i spill aktiviteter og oppgaver som kan adaptere fag, forskning, didaktikk og teori til klasserom og profesjonen. Utforming og montasje av de ulike delene eller episodene i et undervisningsforløp kan betegnes som undervisningsforløpets dramaturgi. I denne artikkelen har jeg gjort en dramaturgisk analyse av tre lærerutdanneres undervisning for å identifisere og beskrive hvordan de bruker eksplisitte modelleringsformer, og hva som skjer når de bruker dem. I etterkant av den dramaturgiske analysen har jeg gjort en konvensjonell innholdsanalyse av intervjudata for å undersøke hvordan lærerutdannerne selv forklarer formålet og erfaringer med å bruke eksplisitt modellering i undervisningen. Analyse av tre lærerutdanneres undervisningspraksis sammenfattes i en modelleringsstige som visualiserer hvordan enkelte former for eksplisitte modelleringsformer tilbyr en egen sirkulær dramaturgi. Studien antyder og drøfter også på hvilken måte modelleringsstigen kan fungere som en dramaturgisk modell, som kan brukes som utgangspunkt for lærerutdanneres planlegging, gjennomføring og analyse av egen undervisning. Studien er et bidrag til å utvikle og forske på hvordan eksplisitte modelleringsformer kan brukes for å skape sammenheng mellom praktisk lærerarbeid og teoretisk metarefleksjon i lærerutdannerens undervisning. Innsamling av data er gjort i profesjonsverksted, som kan forklares som en læringsarena hvor lærerutdannere fra ulike fag samarbeider om

  9. Rate-adaptive AV delay and exercise performance following cardiac resynchronization therapy.

    Science.gov (United States)

    Shanmugam, Nesan; Prada-Delgado, Oscar; Campos, Ana Garcia; Grimster, Alex; Valencia, Oswaldo; Baltabaeva, Aigul; Jones, Sue; Anderson, Lisa

    2012-11-01

    Physiological shortening of the atrioventricular (AV) interval with increasing heart rate is well documented in normal human beings and is an established component of dual-chamber pacing for bradycardia. To assess the effect of exercise on optimal AV delay and the impact of a patient-specific rate-adaptive AV delay (RAAVD) on exercise capacity in patients with heart failure following cardiac resynchronization therapy. Phase 1: We performed iterative AV optimization at rest and exercise in 52 cardiac resynchronization therapy patients in atrial-sensed mode (mean age 71.6 ± 9.2 years, 25% females). Phase 2: Subsequently, 20 consecutive volunteers from this group (mean age 69.2 ± 9.6 years, 15% females) underwent cardiopulmonary exercise testing with RAAVD individually programmed ON (RAAVD-ON) or OFF (RAAVD-OFF). Phase 1: In 94% of the patients, there was a marked reduction (mean 50%) in optimal AV delay with exercise. The optimal resting vs exercise AV delay was 114.2 ± 29 ms at a heart rate of 64.4 ± 7.1 beats/min vs 57 ± 31 ms at a heart rate of 103 ± 13 beats/min (P AV delay with exercise, and 3 (6%) showed no change. Phase 2: With RAAVD-ON, significantly better exercise times were achieved (8.7 ± 3.2 minutes) compared with RAAVD-OFF (7.9 ± 3.2 minutes; P = .003), and there was a significant improvement in Vo(2)max (RAAVD-ON 16.1 ± 4.0 vs RAAVD-OFF 14.9 ± 3.7 mL/(kg · min); P = .024). There was a dramatic reduction in optimal AV delay with physiological exercise in the majority of this heart failure cardiac resynchronization therapy cohort. Replicating this physiological response with a programmable RAAVD translated into a 10% improvement in exercise capacity. Copyright © 2012 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  10. Correlliansk Wicca -En analyse av et nyreligiøst trossamfunn i vekst-

    OpenAIRE

    Johansen, Monica Frankrig

    2015-01-01

    Correlliansk wicca er en tradisjon innenfor wicca som baserer sin praksis på læren til High- Correll familien. Den correllianske wicca- tradisjonen ble grunnlagt av Caroline High- Correll. Correllianere anser seg selv for å være åpne for mange ulike livssyn og praksiser. De tror at det guddommelige kommer innenfra oss selv, og at religion eksisterer for å hjelpe oss til å finne det guddommelige i hver av oss, og ikke for å forsøke å erstatte denne guddommeligheten. Correllianere mener at alle...

  11. Hvordan gjøre tenking synlig ved bruk av interaktive modeller på vitensenter?

    OpenAIRE

    Stav, Torun Vaagland

    2015-01-01

    Det er et økende antall forskningsstudier som fokuserer på læringsutbytte ved vitensentre og liknende institusjoner (Kisiel, 2013). EEET (European Exhibition Evaluation Tool) er et slikt bidrag. Dette er et vurderingsverktøy som blant annet er laget for å kartlegge bruken av interaktive modeller ved vitensentre. EEETer en av to metoder som skal bidra til å besvare denne studiens problemstilling. Den andre metoden, UM (Understanding Map) er basert på åtte tegn på forståelse som beskrevet i bok...

  12. Konstruktion av vertikaltransportör för materialhantering

    OpenAIRE

    Furu, Micke

    2012-01-01

    Rotab Rostfria Transportörer AB tillverkar och utvecklar material- och godshanteringsutrustning. Företaget levererar även kompletta materialhanteringslösningar i form av godshanteringsanläggningar som ofta består av transportband och paketeringsutrustning. Examensarbetets mål är att utveckla en vertikaltransportör som ska transportera gods mellan två transportband belägna på olika höjder, transporten ska kunna varieras mellan 1000 - 3000 mm. Transportören ska undvika de två stora nackdelarna ...

  13. Att vara ung vuxen med reumatism : Psykologiska aspekter av reumatisk sjukdom

    OpenAIRE

    Fröberg, Tove

    2015-01-01

    Kunskapen gällande hur det upplevs att vara ung vuxen och samtidigt ha en reumatisk sjukdom är begränsad. Syftet med denna kvalitativa studie var att utifrån individens eget perspektiv försöka fånga in och beskriva olika psykologiska aspekter av att vara ung vuxen och samtidigt ha reumatism, i en svensk kontext. Studien utfördes på sju reumatiker i åldern 18-40 och datainsamligen bestod av semistrukturerade intervjuer. Analysen följde ett induktivt tematiskt mönster. I studien identifierades ...

  14. Indeksering av og søking i hierarkiske metadata i XML-database

    OpenAIRE

    Ingebretsen, Knut Bjørke

    2005-01-01

    Denne oppgaven ser på hvordan en XML-database kan brukes til indeksering av og søking i hierarkiske metadata. Dette inngår som en del av arbeidet med å gjøre informasjon fra forskjellige samlinger tilgjengelig for informasjonssøkere. Problemstillingen det har vært arbeidet med er delt i to. Den ene delen var å finne ut hvordan en XML-database kan brukes som lokal indeks for metadata på et hierarkisk format. Den andre delen var å finne ut hvordan et søkegrensesnitt kan utvides til å utnytte h...

  15. Manliga och kvinnliga teknologers självbilder och deras stereotypbilder av teknologer

    Directory of Open Access Journals (Sweden)

    Charlotte Soneson

    2013-01-01

    Full Text Available Självbild och bilden av en typisk teknolog undersöktes hos civilingenjörsstudenter på LTH med personlighetstestet Adjective Check List. Vi fann stora skillnader mellan självbild och stereotypbild. Undersökningen visade också att dessa skillnader till viss del såg olika ut bland manliga och kvinnliga studenter, och skillnaden mellan kvinnornas genomsnittliga självbild och deras genomsnittliga bild av en typisk teknolog var då större än motsvarande skillnad bland männen.

  16. Inversion of e-simple Block Matrices

    Czech Academy of Sciences Publication Activity Database

    Fiedler, Miroslav

    2005-01-01

    Roč. 400, - (2005), s. 231-241 ISSN 0024-3795 R&D Projects: GA AV ČR IAA1030302 Institutional research plan: CEZ:AV0Z10300504 Keywords : matrix inversion * M-matrix * unipathic graph * e-simple graph Subject RIV: BA - General Mathematics Impact factor: 0.590, year: 2005

  17. BioBlocks: Programming Protocols in Biology Made Easier.

    Science.gov (United States)

    Gupta, Vishal; Irimia, Jesús; Pau, Iván; Rodríguez-Patón, Alfonso

    2017-07-21

    The methods to execute biological experiments are evolving. Affordable fluid handling robots and on-demand biology enterprises are making automating entire experiments a reality. Automation offers the benefit of high-throughput experimentation, rapid prototyping, and improved reproducibility of results. However, learning to automate and codify experiments is a difficult task as it requires programming expertise. Here, we present a web-based visual development environment called BioBlocks for describing experimental protocols in biology. It is based on Google's Blockly and Scratch, and requires little or no experience in computer programming to automate the execution of experiments. The experiments can be specified, saved, modified, and shared between multiple users in an easy manner. BioBlocks is open-source and can be customized to execute protocols on local robotic platforms or remotely, that is, in the cloud. It aims to serve as a de facto open standard for programming protocols in Biology.

  18. Analysis of Separated Flow over Blocked Surface

    Directory of Open Access Journals (Sweden)

    Onur YEMENİCİ

    2013-04-01

    Full Text Available In this study, the separated flow over flat and blocked surfaces was investigated experimentally. Velocity and turbulence intensity measurements were carried out by a constanttemperature hot wire anemometer and static pressure measurements by a micro-manometer. The flow separations and reattachments were occurred before the first block, on the first block, between blocks and after the last block, and the presence of the blocks significantly increased the turbulent intensity

  19. Effect of molecular structure of styrene-butadiene block copolymers on morphology, rheological properties and impact strength of polystyrene/polyethylene blends

    Czech Academy of Sciences Publication Activity Database

    Fortelný, Ivan; Mikešová, Jana; Hromádková, Jiřina; Hašová, Věra; Horák, Zdeněk

    2003-01-01

    Roč. 90, č. 9 (2003), s. 2303-2309 ISSN 0021-8995 R&D Projects: GA ČR GA106/99/0555; GA ČR GA106/99/0556 Institutional research plan: CEZ:AV0Z4050913 Keywords : blends * compatibilization * block copolymers Subject RIV: JI - Composite Materials Impact factor: 1.017, year: 2003

  20. Effect of the selected structural parameters of styrene-butadiene block copolymers on their compatibilization efficiency in polystyrene/polybutadiene blends

    Czech Academy of Sciences Publication Activity Database

    Horák, Zdeněk; Hlavatá, Drahomíra; Hromádková, Jiřina; Kotek, Jiří; Hašová, Věra; Mikešová, Jana; Pleska, A.

    2002-01-01

    Roč. 40, č. 23 (2002), s. 2612-2623 ISSN 0887-6266 R&D Projects: GA ČR GA106/99/0556 Institutional research plan: CEZ:AV0Z4050913 Keywords : polystyrene/polybutadiene blends -compatibilization * block copolymers Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.221, year: 2002

  1. Synthesis and pH- and salinity-controlled self-assembly of novel amphiphilic block-gradient copolymers of styrene and acrylic acid

    Czech Academy of Sciences Publication Activity Database

    Borisova, O.; Billon, L.; Zaremski, M.; Grassl, B.; Bakaeva, Zulfiya; Lapp, A.; Štěpánek, Petr; Borisov, O.

    2012-01-01

    Roč. 8, č. 29 (2012), s. 7649-7659 ISSN 1744-683X R&D Projects: GA ČR GAP208/10/1600 Institutional research plan: CEZ:AV0Z40500505 Keywords : block-gradient copolymers * light scattering * small-angle neutron scattering Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.909, year: 2012

  2. Vad var det som hände? Efterbearbetning av en simulering för utvecklande av professionell kunskap hos polisstudenter

    Directory of Open Access Journals (Sweden)

    David Sjöberg

    2014-11-01

    Full Text Available Att öva för att lära sig att hantera polisiära situationer utgör ett viktigt inslag i polisstudenters utbildning. Lärandet sker genom praktiska övningar t.ex. drillövningar och övningar av specifika moment men även via simuleringar där studenter agerar som polis i mera komplexa situationer. Simuleringar är inte unika för polisutbildning utan utgör ett vanligt inslag i professionsutbildning genom sin koppling till "verkliga" situationer (Peters och Vissers, 2004; Lederman, 1984. Under de senaste årtiondena har simuleringar använts för utbildning inom så skilda professionsfält som medicin och hälsovård, flyg och blåljusverksamhet. Simuleringar kan vara av skiftande karaktär t.ex. fysiska i form av rollspel men även datorbaserade. Simuleringar kan syfta till att utveckla en specifik färdighet (se t.ex. Windsor, 2009; Stefanidis, Acker, och Heniford, 2008; Wallin, Meurling, Hedman, Hedengård, och Felländer-Tsai, 2007, som t ex att lära sig hur man avläser röntgenbilder (se t.ex. Söderström, Häll, Nilsson, och Ahlqvist 2012 eller till att lära hur man ska agera i komplexa situationer (Andersson, Carlström, och Berlin, 2013; Bauman, Gohm och Bonner, 2011, t.ex. vid svåra olyckshändelser med många personer inblandade (se t.ex. McConnell och Drennan, 2006. Simuleringar av komplexa situationer med många inblandade brukar benämnas som fullskaliga (se t.ex. Andersson, Carlström, och Berlin, 2013. Simuleringar antas träna och utveckla professionell kunskap genom att förbereda studenter på att hantera komplexa och ibland farliga situationer som de kan komma att ställas inför i en kommande yrkespraktik. Användningen av simuleringar i utbildningar bygger således på ett antagande om överföring av erfarenheter och kunskaper från ett sammanhang till ett annat (se t.ex. Söderström, Åström, Anderson och Bowles, 2014. I den här artikeln utgår vi från simulering som en utbildningsresurs där deltagarna

  3. Vannmagasinet er ikke fullt før det renner over : en analyse av effekten av redusert etterspørsel i et vannkraftsystem, eksemplifisert med energieffektivisering i bygninger

    OpenAIRE

    Siljan, Marte

    2010-01-01

    Energieffektivisering i bygninger regnes som et av de mest kostnadseffektive tiltakene for å redusere forbruk av energi, samt bidra til reduksjon i klimagassutslipp. I følge rapporter fra blant annet Lavenergiutvalget (2009) og Klimakur 2020 (2010), vil det være mulig å frigjøre rundt 10 TWh elektrisitet fra norske bygninger i løpet av de neste ti årene. Denne masteroppgaven tar for seg følgene av en tilsvarende etterspørselsreduksjon i det norske kraftsystemet. Norge har et kraftsystem med n...

  4. Various semiclassical limits of torus conformal blocks

    Energy Technology Data Exchange (ETDEWEB)

    Alkalaev, Konstantin [I.E. Tamm Department of Theoretical Physics, P.N. Lebedev Physical Institute,Leninsky ave. 53, Moscow, 119991 (Russian Federation); Department of General and Applied Physics, Moscow Institute of Physics and Technology,Institutskiy per. 7, Dolgoprudnyi, Moscow region, 141700 (Russian Federation); Geiko, Roman [Mathematics Department, National Research University Higher School of Economics,Usacheva str. 6, Moscow, 119048 (Russian Federation); Rappoport, Vladimir [I.E. Tamm Department of Theoretical Physics, P.N. Lebedev Physical Institute,Leninsky ave. 53, Moscow, 119991 (Russian Federation); Department of Quantum Physics, Institute for Information Transmission Problems,Bolshoy Karetny per. 19, Moscow, 127994 (Russian Federation)

    2017-04-12

    We study four types of one-point torus blocks arising in the large central charge regime. There are the global block, the light block, the heavy-light block, and the linearized classical block, according to different regimes of conformal dimensions. It is shown that the blocks are not independent being connected to each other by various links. We find that the global, light, and heavy-light blocks correspond to three different contractions of the Virasoro algebra. Also, we formulate the c-recursive representation of the one-point torus blocks which is relevant in the semiclassical approximation.

  5. Trace metals in floodplain lake sediments : SEM/AVS as indicator of bioavailability and ecological effects

    NARCIS (Netherlands)

    Griethuysen, van C.

    2006-01-01

    This thesis addresses the geochemical aspects of AVS (Acid Volatile Sulfide) and SEM (Simultaneously Extracted Metals) in floodplain lake sediment, its spatial distribution in floodplain lakes and dynamics over time, the link with effects on single species (bioassays), as well as the impact of

  6. In Vivo cortical tau in Parkinson's disease using 18F-AV-1451 positron emission tomography.

    Science.gov (United States)

    Hansen, Allan K; Damholdt, Malene Flensborg; Fedorova, Tatyana D; Knudsen, Karoline; Parbo, Peter; Ismail, Rola; Østergaard, Karen; Brooks, David J; Borghammer, Per

    2017-06-01

    Alzheimer's disease copathology is common in PD at autopsy. In non-PD subjects with mild cognitive impairment, tau depositions can be detected using 18F-AV-1451 PET. We hypothesized that 18F-AV-1451 PET would show tau aggregation in PD with mild cognitive impairment and correlate with cognitive dysfunction. To describe tau aggregation in PD patients. Twenty-six PD patients and 23 controls had 18F-AV-1451 PET and neuropsychological assessment to detect mild cognitive impairment. Nine PD patients (35%) were identified with mild cognitive impairment. Regional analyses showed no significant differences between groups. Voxel-wise analyses showed no correlation with cognitive domain z-scores within patients. One patient with mild cognitive impairment was estimated Braak tau stage 5; all other patients were stage 0. Our results indicate that tau pathology, as detected by 18F-AV-1451, is uncommon in PD with mild cognitive impairment and shows no significant correlation with cognitive dysfunction at this stage. © 2017 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and Movement Disorder Society.

  7. A-V Delay Versus Cardiac Output Measured with Thorax Bioimpedance Monitor

    Czech Academy of Sciences Publication Activity Database

    Vondra, Vlastimil; Halámek, Josef; Viščor, Ivo; Jurák, Pavel; Novák, M.; Lipoldová, J.

    2008-01-01

    Roč. 6, č. 1 (2008), s. 73 ISSN 1556-7451. [World Congress on Heart Disease /14./. 26.07.2008-29.07.2008, Toronto] Institutional research plan: CEZ:AV0Z20650511 Keywords : atrio -ventricular delay * resynchronization therapy * impedance cardiography * cardiac output Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  8. Identification of a potential toxic hot spot associated with AVS spatial and seasonal variation.

    Science.gov (United States)

    Campana, O; Rodríguez, A; Blasco, J

    2009-04-01

    In risk assessment of aquatic sediments, much attention is paid to the difference between acid-volatile sulfide (AVS) and simultaneously extracted metals (SEMs) as indicators of metal availability. Ten representative sampling sites were selected along the estuary of the Guadalete River. Surficial sediments were sampled in winter and summer to better understand SEM and AVS spatial and seasonal distributions and to establish priority risk areas. Total SEM concentration (SigmaSEM) ranged from 0.3 to 4.7 micromol g(-1). It was not significantly different between seasons, however, it showed a significant difference between sampling stations. AVS concentrations were much more variable, showing significant spatial and temporal variations. The values ranged from 0.8 to 22.4 micromol g(-1). The SEM/AVS ratio was found to be <1 at all except one station located near the mouth of the estuary. The results provided information on a potential pollution source near the mouth of the estuary, probably associated with vessel-related activities carried out in a local harbor area located near the station.

  9. Nové elektronické knihy v Knihovně AV ČR

    Czech Academy of Sciences Publication Activity Database

    Meixner, Jaroslav; Krouzová, Lucie

    -, č. 2 (2014) E-ISSN 1805-2800 Keywords : electronic books * Academy of Sciences Lib rary Subject RIV: AF - Documentation, Lib rarianship, Information Studies http://www. lib .cas.cz/casopis-informace/nove-elektronicke-knihy-v-knihovne-av-cr/

  10. Impact of e-AV Biology Website for Learning about Renewable Energy

    Science.gov (United States)

    Nugraini, Siti Hadiati; Choo, Koo Ah; Hin, Hew Soon; Hoon, Teoh Sian

    2013-01-01

    This paper considers the design and development of a Website for Biology in senior high schools in Indonesia. The teaching media, namely e-AV Biology, was developed with the main features of video lessons and other features in supporting the students' learning process. Some video lessons describe the production process of Biofuel or Renewable…

  11. Problematika romské migrace v Etnologickém ústavu AV ČR

    Czech Academy of Sciences Publication Activity Database

    Uherek, Zdeněk

    2007-01-01

    Roč. 10, č. 3 (2007), s. 1-7 ISSN 1335-3608 Institutional research plan: CEZ:AV0Z90580513 Keywords : migration * Roma * Institute of Ethnology of the Academy of Sciences of the Czech Republic Subject RIV: AC - Archeology, Anthropology, Ethnology http://www.saske.sk/cas/3-2007/index.html

  12. ECG of the "Newborn" Mouse (Mus domesticus) with Specific Reference to Comparative AV Transmission

    NARCIS (Netherlands)

    Tweel, L.H. van der; Strackee, J.; Stokhof, A.A.; Wassenaar, C.; Meijler, F.L.

    1999-01-01

    The objective of this study was to record the ECG of the smallest living mammal to extend the domain of data for comparative AV-nodal electrophysiologic purposes. These data are needed to establish the relationship between the PR interval and heart size in mammalian species of all sizes. Methods

  13. Identification of the human ApoAV gene as a novel RORα target gene

    International Nuclear Information System (INIS)

    Lind, Ulrika; Nilsson, Tina; McPheat, Jane; Stroemstedt, Per-Erik; Bamberg, Krister; Balendran, Clare; Kang, Daiwu

    2005-01-01

    Retinoic acid receptor-related orphan receptor-α (RORα) (NR1F1) is an orphan nuclear receptor with a potential role in metabolism. Previous studies have shown that RORα regulates transcription of the murine Apolipoprotein AI gene and human Apolipoprotein CIII genes. In the present study, we present evidence that RORα also induces transcription of the human Apolipoprotein AV gene, a recently identified apolipoprotein associated with triglyceride levels. Adenovirus-mediated overexpression of RORα increased the endogenous expression of ApoAV in HepG2 cells and RORα also enhanced the activity of an ApoAV promoter construct in transiently transfected HepG2 cells. Deletion and mutation studies identified three AGGTCA motifs in the ApoAV promoter that mediate RORα transactivation, one of which overlaps with a previously identified binding site for PPARα. Together, these results suggest a novel mechanism whereby RORα modulates lipid metabolism and implies RORα as a potential target for the treatment of dyslipidemia and atherosclerosis

  14. HPCMP CREATE (trademark)-AV Quality Assurance: Best Practices for Validating and Supporting Computation-Based Engineering Software

    Science.gov (United States)

    2015-09-30

    30/2015 Oct 2008-Sep 2015 HPCMP CREATE™- AV Quality Assurance: Best Practices for Validating and Supporting Computation-Based Engineering Software...2) “Does this tool adequately perform any and all advertised capabilities?” This paper will describe how the HPCMP CREATE Air Vehicles ( AV ...discussed and their strengths and weaknesses within the CREATE- AV framework addressed. Work toward the HPCMP CREATE, Quality Assurance, Aviation

  15. Compaction of full size blocks of bentonite for the KBS-3 concept. Initial tests for evaluating the technique

    International Nuclear Information System (INIS)

    Johanesson, Lars-Erik

    1999-12-01

    Besides the test with the compaction device several other pieces of equipment were tested for the mixing of the bentonite with water, filling of the form with bentonite and lifting of the blocks. The tests of the equipment turned out well. Furthermore the density of the compacted bentonite was in parity with the expected. The compacted blocks had grooves and flanges in order to facilitate the emplacement of the blocks. Unacceptable damages and cracks close to the flanges were observed on the blocks with low water ratio. As a consequence of these damages it is recommended that the form is modified so that blocks with plane surfaces can be made

  16. AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure.

    Science.gov (United States)

    Mishra, Shruti; Gordon, Brian A; Su, Yi; Christensen, Jon; Friedrichsen, Karl; Jackson, Kelley; Hornbeck, Russ; Balota, David A; Cairns, Nigel J; Morris, John C; Ances, Beau M; Benzinger, Tammie L S

    2017-11-01

    Utilizing [18F]-AV-1451 tau positron emission tomography (PET) as an Alzheimer disease (AD) biomarker will require identification of brain regions that are most important in detecting elevated tau pathology in preclinical AD. Here, we utilized an unsupervised learning, data-driven approach to identify brain regions whose tau PET is most informative in discriminating low and high levels of [18F]-AV-1451 binding. 84 cognitively normal participants who had undergone AV-1451 PET imaging were used in a sparse k-means clustering with resampling analysis to identify the regions most informative in dividing a cognitively normal population into high tau and low tau groups. The highest-weighted FreeSurfer regions of interest (ROIs) separating these groups were the entorhinal cortex, amygdala, lateral occipital cortex, and inferior temporal cortex, and an average SUVR in these four ROIs was used as a summary metric for AV-1451 uptake. We propose an AV-1451 SUVR cut-off of 1.25 to define high tau as described by imaging. This spatial distribution of tau PET is a more widespread pattern than that predicted by pathological staging schemes. Our data-derived metric was validated first in this cognitively normal cohort by correlating with early measures of cognitive dysfunction, and with disease progression as measured by β-amyloid PET imaging. We additionally validated this summary metric in a cohort of 13 Alzheimer disease patients, and showed that this measure correlates with cognitive dysfunction and β-amyloid PET imaging in a diseased population. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Videodokumentasjon ved gjennomføring av praktisk eksamen i sykepleie - hvordan kan dette forbedre studentens praksiske ferdigheter?

    Directory of Open Access Journals (Sweden)

    Gjertrud Husøy

    2014-02-01

    Full Text Available Hensikten med studiet var å belyse hvordan videodokumentasjon av praktiske handlinger i sykepleie kunne brukes som evalueringordning av studenter. Artikkelen tar utgangspunkt i et forskningsprosjekt for utprøving av nye lærings og evalueringsformer i bachelorutdanningen i sykepleie, der 13 studentgrupper gjennomførte sin praktiske eksamen ved innlevering av video av 16 utvalgte øvelser. Tradisjonell praktisk eksamen i samme studentkull ble gjennomført for 10 studentgrupper. Prosjektet er en kvalitativ kasusstudie og analyse er gjort etter inspirasjon av Giorgi‘s empiriske fenomenologi. Diskusjonen tar utgangspunkt i Vygotsky‘s sosiokulturelle syn på læring og Dewey‘s prinsipp om at all læring er basert på erfaring. Funnene er presentert i følgende deler: Første del omhandler videodokumentasjon og refleksjon. De to neste delene viser funn i forhold til mesterlæring og situert læring på vei mot forståelse av hva sykepleie er. Deretter er teknisk utfordringer belyst, og til slutt en drøfting av forhold ved oppøving av praktiske sykepleieferdigheter. Konklusjonen her er at video egner seg til å dokumentere sykepleiehandlinger. Dette har størst verdi for læring og refleksjon, i mindre grad som eksamensform.

  18. Radial Coordinates for Conformal Blocks

    CERN Document Server

    Hogervorst, Matthijs

    2013-01-01

    We develop the theory of conformal blocks in CFT_d expressing them as power series with Gegenbauer polynomial coefficients. Such series have a clear physical meaning when the conformal block is analyzed in radial quantization: individual terms describe contributions of descendants of a given spin. Convergence of these series can be optimized by a judicious choice of the radial quantization origin. We argue that the best choice is to insert the operators symmetrically. We analyze in detail the resulting "rho-series" and show that it converges much more rapidly than for the commonly used variable z. We discuss how these conformal block representations can be used in the conformal bootstrap. In particular, we use them to derive analytically some bootstrap bounds whose existence was previously found numerically.

  19. Diversity Gain through Antenna Blocking

    Directory of Open Access Journals (Sweden)

    V. Dehghanian

    2012-01-01

    Full Text Available As part of the typical usage mode, interaction between a handheld receiver antenna and the operator's RF absorbing body and nearby objects is known to generate variability in antenna radiation characteristics through blocking and pattern changes. It is counterintuitive that random variations in blocking can result in diversity gain of practical applicability. This diversity gain is quantified from a theoretical and experimental perspective. Measurements carried out at 1947.5 MHz verify the theoretical predictions, and a diversity gain of 3.1 dB was measured through antenna blocking and based on the utilized measurement setup. The diversity gain can be exploited to enhance signal detectability of handheld receivers based on a single antenna in indoor multipath environments.

  20. Cryptanalysis of Selected Block Ciphers

    DEFF Research Database (Denmark)

    Alkhzaimi, Hoda A.

    , pseudorandom number generators, and authenticated encryption designs. For this reason a multitude of initiatives over the years has been established to provide a secure and sound designs for block ciphers as in the calls for Data Encryption Standard (DES) and Advanced Encryption Standard (AES), lightweight...... ciphers initiatives, and the Competition for Authenticated Encryption: Security, Applicability, and Robustness (CAESAR). In this thesis, we first present cryptanalytic results on different ciphers. We propose attack named the Invariant Subspace Attack. It is utilized to break the full block cipher...... on the family of lightweight block cipher SIMON that was published by the U.S National Security Agency (NSA). The ciphers are developed with optimization towards both hardware and software in mind. While the specification paper discusses design requirements and performance of the presented lightweight ciphers...

  1. Climatological features of blocking anticyclones

    International Nuclear Information System (INIS)

    Lupo, A.R.; Smith, P.J.; Oglesby, R.J.

    1994-01-01

    Several climatological studies have been previously performed using large observational data sets (i.e., 10 years or longer) in order to determine the predominant characteristics of blocking anticyclones, including favored development regions, duration, preferred seasonal occurrence, and frequency of occurrence. These studies have shown that blocking anticyclones occur most frequently from October to April over the eastern Atlantic and Pacific oceans downstream from both the North American and Asian continental regions and the storm track regions to the east of these continents. Some studies have also revealed the presence of a third region block formation in western Russia near 40 degrees E which is associated with another storm track region over the Mediterranean and western Asia

  2. Projectors, shadows, and conformal blocks

    Energy Technology Data Exchange (ETDEWEB)

    Simmons-Duffin, David [Jefferson Physical Laboratory, Harvard University,Cambridge, MA 02138 (United States)

    2014-04-24

    We introduce a method for computing conformal blocks of operators in arbitrary Lorentz representations in any spacetime dimension, making it possible to apply bootstrap techniques to operators with spin. The key idea is to implement the “shadow formalism' of Ferrara, Gatto, Grillo, and Parisi in a setting where conformal invariance is manifest. Conformal blocks in d-dimensions can be expressed as integrals over the projective null-cone in the “embedding space' ℝ{sup d+1,1}. Taking care with their analytic structure, these integrals can be evaluated in great generality, reducing the computation of conformal blocks to a bookkeeping exercise. To facilitate calculations in four-dimensional CFTs, we introduce techniques for writing down conformally-invariant correlators using auxiliary twistor variables, and demonstrate their use in some simple examples.

  3. Genetically modified tumour vaccines

    Czech Academy of Sciences Publication Activity Database

    Bubeník, Jan

    2005-01-01

    Roč. 3, Suppl. 1 (2005), S7 ISSN 1214-021X. [Cells VI - Biological Days /18./. 24.10.2005-26.10.2005, České Budějovice] Institutional research plan: CEZ:AV0Z50520514 Keywords : tumour vaccines * HPV16 Subject RIV: EC - Immunology

  4. Polyurethane latex modified with polyaniline

    Czech Academy of Sciences Publication Activity Database

    Sapurina, I.; Stejskal, Jaroslav; Špírková, Milena; Kotek, Jiří; Prokeš, J.

    2005-01-01

    Roč. 151, č. 2 (2005), s. 93-99 ISSN 0379-6779 R&D Projects: GA AV ČR IAA4050313; GA AV ČR KSK4050111 Grant - others:Russian Academy of Sciences(RU) 01-04/391 Institutional research plan: CEZ:AV0Z40500505 Keywords : conducting polymer * colloid * colloidal dispersion Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.320, year: 2005

  5. Projectors, Shadows, and Conformal Blocks

    OpenAIRE

    Simmons-Duffin, David

    2012-01-01

    We introduce a method for computing conformal blocks of operators in arbitrary Lorentz representations in any spacetime dimension, making it possible to apply bootstrap techniques to operators with spin. The key idea is to implement the “shadow formalism” of Ferrara, Gatto, Grillo, and Parisi in a setting where conformal invariance is manifest. Conformal blocks in d -dimensions can be expressed as integrals over the projective null-cone in the “embedding space” $ \\mathbb{R} $ d +1,1 . Taking ...

  6. Skladování energie – téma v hledáčku AV ČR

    Czech Academy of Sciences Publication Activity Database

    Bendová, Magdalena; Hrubý, Jan; Chomát, Miroslav; Zima, Patrik

    -, č. 2 (2016), s. 7-9 ISSN 1210-9525. [Technology Perspectives for Energy Storage. Praha, 30.11.2015] Grant - others:AV ČR(CZ) StrategieAV21/3 Program:StrategieAV Institutional support: RVO:61388998 ; RVO:67985858 Keywords : energy storage * renewable energy sources * strategy AV21 initiative Subject RIV: CF - Physical ; Theoretical Chemistry

  7. Morphology of polystyrene-block-poly(styrene-co-acrylonitrile) and polystyrene-block-poly(styrene-co-acrylonitrile-co-5-vinyltetrazole) diblock copolymers prepared by nitroxide-mediated radical polymerization and „click“ chemistry

    Czech Academy of Sciences Publication Activity Database

    Gromadzki, Daniel; Lokaj, Jan; Černoch, Peter; Diat, O.; Nallet, F.; Štěpánek, Petr

    2008-01-01

    Roč. 44, č. 1 (2008), s. 189-199 ISSN 0014-3057 R&D Projects: GA ČR GESON/06/E005 Grant - others: Marie Curie Fellowship(EU) HPMT-CT-2001-00396 Institutional research plan: CEZ:AV0Z40500505 Keywords : polystyrene-block-poly(styrene-co-acrylonitrile-co-5-vinyltetrazole) * TEMPO * click chemistry Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.143, year: 2008

  8. The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity.

    Science.gov (United States)

    Bailleul, Geoffrey; Kravtzoff, Amanda; Joulin-Giet, Alix; Lecaille, Fabien; Labas, Valérie; Meudal, Hervé; Loth, Karine; Teixeira-Gomes, Ana-Paula; Gilbert, Florence B; Coquet, Laurent; Jouenne, Thierry; Brömme, Dieter; Schouler, Catherine; Landon, Céline; Lalmanach, Gilles; Lalmanach, Anne-Christine

    2016-01-01

    Defensins are frontline peptides of mucosal immunity in the animal kingdom, including birds. Their resistance to proteolysis and their ensuing ability to maintain antimicrobial potential remains questionable and was therefore investigated. We have shown by bottom-up mass spectrometry analysis of protein extracts that both avian beta-defensins AvBD2 and AvBD7 were ubiquitously distributed along the chicken gut. Cathepsin B was found by immunoblotting in jejunum, ileum, caecum, and caecal tonsils, while cathepsins K, L, and S were merely identified in caecal tonsils. Hydrolysis product of AvBD2 and AvBD7 incubated with a panel of proteases was analysed by RP-HPLC, mass spectrometry and antimicrobial assays. AvBD2 and AvBD7 were resistant to serine proteases and to cathepsins D and H. Conversely cysteine cathepsins B, K, L, and S degraded AvBD2 and abolished its antibacterial activity. Only cathepsin K cleaved AvBD7 and released Ile4-AvBD7, a N-terminal truncated natural peptidoform of AvBD7 that displayed antibacterial activity. Besides the 3-stranded antiparallel beta-sheet typical of beta-defensins, structural analysis of AvBD7 by two-dimensional NMR spectroscopy highlighted the restricted accessibility of the C-terminus embedded by the N-terminal region and gave a formal evidence of a salt bridge (Asp9-Arg12) that could account for proteolysis resistance. The differential susceptibility of avian defensins to proteolysis opens intriguing questions about a distinctive role in the mucosal immunity against pathogen invasion.

  9. Preconditioning of matrices partitioned in 2 x 2 block form: Eigenvalue estimates and Schwarz DD for mixed FEM

    Czech Academy of Sciences Publication Activity Database

    Axelsson, Owe; Blaheta, Radim

    2010-01-01

    Roč. 17, č. 5 (2010), s. 787-810 ISSN 1070-5325 R&D Projects: GA ČR GA105/09/1830 Institutional research plan: CEZ:AV0Z30860518 Keywords : iterative solution methods * saddle point problems * preconditioning block matrices * domain decomposition * heterogeneous problems * regularization Subject RIV: JC - Computer Hardware ; Software Impact factor: 1.163, year: 2010 http://onlinelibrary.wiley.com/doi/10.1002/nla.v17:5/issuetoc

  10. Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients.

    Science.gov (United States)

    Vijayvergiya, Rajesh; Gupta, Ankur

    2015-11-26

    To compare the atrio-ventricular (AV/PV) delay optimization by echocardiography and intra-cardiac electrocardiogram (IEGM) based QuickOpt algorithm in complete heart block (CHB) patients, implanted with a dual chamber pacemaker. We prospectively enrolled 20 patients (age 59.45 ± 18.1 years; male: 65%) with CHB, who were implanted with a dual chamber pacemaker. The left ventricular outflow tract velocity time-integral was measured after AV/PV delay optimization by both echocardiography and QuickOpt algorithm method. Bland-Altman analysis was used for agreement between the two techniques. The optimal AV and PV delay determined by echocardiography was 155.5 ± 14.68 ms and 122.5 ± 17.73 ms (P < 0.0001), respectively and by QuickOpt method was 167.5 ± 16.73 and 117.5 ms ± 9.10 ms (P < 0.0001), respectively. A good agreement was observed between optimal AV and PV delay as measured by two methods. However, the correlation of the optimal AV (r = 0.0689, P = 0.77) and PV (r = 0.2689, P = 0.25) intervals measured by the two techniques was poor. The time required for AV/PV optimization was 45.26 ± 1.73 min by echocardiography and 0.44 ± 0.08 min by QuickOpt method (P < 0.0001). The programmer based IEGM method is an automated, quick, easier and reliable alternative to echocardiography for the optimization of AV/PV delay in CHB patients, implanted with a dual chamber pacemaker.

  11. Genetically modified cellular vaccines for therapy of human papilloma virus type 16 (HPV 16)-associated tumours

    Czech Academy of Sciences Publication Activity Database

    Bubeník, Jan

    2008-01-01

    Roč. 8, č. 3 (2008), s. 180-186 ISSN 1568-0096 Grant - others:EU-FP6-NoE Clinigene(XE) 018933 Institutional research plan: CEZ:AV0Z50520514 Keywords : HPV 16 * genetically modified vaccines Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.316, year: 2008

  12. Genetically modified vaccines augment the efficacy of cancer surgery and chemotherapy

    Czech Academy of Sciences Publication Activity Database

    Bubeník, Jan

    2009-01-01

    Roč. 55, č. 6 (2009), s. 199-200 ISSN 0015-5500 Institutional research plan: CEZ:AV0Z50520514 Keywords : gene tically modified vaccines * cancer surgery and chemotherapy Subject RIV: EB - Gene tics ; Molecular Biology Impact factor: 0.924, year: 2009

  13. Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases

    Czech Academy of Sciences Publication Activity Database

    Macíčková-Cahová, Hana; Hocek, Michal

    2009-01-01

    Roč. 37, č. 22 (2009), s. 7612-7622 ISSN 0305-1048 R&D Projects: GA ČR GA203/09/0317; GA MŠk LC512 Institutional research plan: CEZ:AV0Z40550506 Keywords : functionalized DNA * restriction endonucleases * DNA polymerase * modified adenosines Subject RIV: CC - Organic Chemistry Impact factor: 7.479, year: 2009

  14. Determining fracture energy parameters of concrete from the modified compact tension test

    Czech Academy of Sciences Publication Activity Database

    Canteli, A.; Castañón, L.; Nieto, B.; Lozano, M.; Holušová, Táňa; Seitl, Stanislav

    2014-01-01

    Roč. 30, OCT (2014), s. 383-393 ISSN 1971-8993 R&D Projects: GA MŠk(CZ) EE2.3.20.0214 Grant - others:interní podpora AV ČR(CZ) M100411204 Institutional support: RVO:68081723 Keywords : Concrete fracture energy * Modified compact tension test * Concrete * Numerical simulation Subject RIV: JL - Materials Fatigue, Friction Mechanics

  15. Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake.

    Science.gov (United States)

    Das, Sandhitsu R; Xie, Long; Wisse, Laura E M; Ittyerah, Ranjit; Tustison, Nicholas J; Dickerson, Bradford C; Yushkevich, Paul A; Wolk, David A

    2018-02-09

    We examined the relationship between in vivo estimates of tau deposition as measured by 18 F-AV-1451 tau positron emission tomography imaging and cross-sectional cortical thickness, as well as rates of antecedent cortical thinning measured from magnetic resonance imaging in individuals with and without evidence of cerebral amyloid in 63 participants from the Alzheimer's Disease Neuroimaging Initiative study, including 32 cognitively normal individuals (mean age 74 years), 27 patients with mild cognitive impairment (mean age 76.8 years), and 4 patients diagnosed with Alzheimer's disease (mean age 80 years). We hypothesized that structural measures would correlate with 18 F-AV-1451 in a spatially local manner and that this correlation would be stronger for longitudinal compared to cross-sectional measures of cortical thickness and in those with cerebral amyloid versus those without. Cross-sectional and longitudinal estimates of voxelwise atrophy were made from whole brain maps of cortical thickness and rates of thickness change. In amyloid-β-positive individuals, the correlation of voxelwise atrophy across the whole brain with a summary measure of medial temporal lobe (MTL) 18 F-AV-1451 uptake demonstrated strong local correlations in the MTL with longitudinal atrophy that was weaker in cross-sectional analysis. Similar effects were seen in correlations between 31 bilateral cortical regions of interest. In addition, several nonlocal correlations between atrophy and 18 F-AV-1451 uptake were observed, including association between MTL atrophy and 18 F-AV-1451 uptake in parietal lobe regions of interest such as the precuneus. Amyloid-β-negative individuals only showed weaker correlations in data uncorrected for multiple comparisons. While these data replicate previous reports of associations between 18 F-AV-1451 uptake and cross-sectional structural measures, the current results demonstrate a strong relationship with longitudinal measures of atrophy. These data

  16. Main-chain supramolecular block copolymers.

    Science.gov (United States)

    Yang, Si Kyung; Ambade, Ashootosh V; Weck, Marcus

    2011-01-01

    Block copolymers are key building blocks for a variety of applications ranging from electronic devices to drug delivery. The material properties of block copolymers can be tuned and potentially improved by introducing noncovalent interactions in place of covalent linkages between polymeric blocks resulting in the formation of supramolecular block copolymers. Such materials combine the microphase separation behavior inherent to block copolymers with the responsiveness of supramolecular materials thereby affording dynamic and reversible materials. This tutorial review covers recent advances in main-chain supramolecular block copolymers and describes the design principles, synthetic approaches, advantages, and potential applications.

  17. Building Blocks for Personal Brands

    Science.gov (United States)

    Thomas, Lisa Carlucci

    2011-01-01

    In this article, the author discusses the four essential building blocks for personal brands: (1) name; (2) message; (3) channels; and (4) bridges. However, outstanding building materials can only take a person so far. The author emphasizes that vision, determination, faith, a sense of humor, and humility are also required.

  18. Control rod removal blocking device

    International Nuclear Information System (INIS)

    Yoshioka, Ritsuo.

    1981-01-01

    Purpose: To prevent excess power increase resulted from erroneous control rod removal during high power operation in BWR type reactor by decreasing the continuous removal enabling distance for the control rods along with increase in the reactor power where the reactor power is greater than a predetermined level. Constitution: When control rod selection signals are supplied from a control unit to a control rod removal blocking device, the blocking device judges whether the reactor core power is greater than a predetermined value A or not, using reactor core power signals outputted from an average power monitor. Where the reactor core power exceeds the predetermined value A and if the reactor core power is relatively low, a large continuous removal enabling distance N 1 is calculated in the blocking device to allow the continuous removal as far as the notch N 1 . The continuous removal enabling distance is shortened as the reactor core power increases and the removal is blocked, for example, at notch N 2 . While on the other hand, if the reactor core power is below the predetermined value A, both of the notchwise removal and the continuous removal are enabled. (Seki, T.)

  19. First Degree Pacemaker Exit Block

    Directory of Open Access Journals (Sweden)

    Johnson Francis

    2016-10-01

    Full Text Available Usually atrial and ventricular depolarizations follow soon after the pacemaker stimulus (spike on the ECG. But there can be an exit block due to fibrosis at the electrode - tissue interface at the lead tip. This can increase the delay between the spike and atrial or ventricular depolarization.

  20. Vagal Blocking for Obesity Control

    DEFF Research Database (Denmark)

    Johannessen, Helene; Revesz, David; Kodama, Yosuke

    2017-01-01

    BACKGROUND: Recently, the US FDA has approved "vagal blocking therapy or vBLoc® therapy" as a new treatment for obesity. The aim of the present study was to study the mechanism-of-action of "VBLOC" in rat models. METHODS: Rats were implanted with VBLOC, an intra-abdominal electrical device...

  1. Thermo-responsive block copolymers

    NARCIS (Netherlands)

    Mocan Cetintas, Merve

    2017-01-01

    Block copolymers (BCPs) are remarkable materials because of their self-assembly behavior into nano-sized regular structures and high tunable properties. BCPs are in used various applications such as surfactants, nanolithography, biomedicine and nanoporous membranes. In these thesis, we aimed to

  2. Scintigraphic visualization of 'Blocking' thyroid

    International Nuclear Information System (INIS)

    Simeonova, A.; Kostadinova, I.

    2006-01-01

    Full text: An important problem in nuclear endocrinology is 'blocking' of thyroid gland, which necessitates postpone of the investigation, adverse clinical effect of stopping medications and a delay of making diagnosis. The aim of the study was to introduce and to determine the clinical value of the scintigraphy with 99mTc-MIBI in patients (Pts) with 'blocked thyroid'. In 365 Pts (aged 38-75 years), indicated for a thyroid scintigraphy after proper preparation, an investigation was performed with 74 MBq 99mTc-pertechnetate, 20 min. p.i. In 14 of them (3.8%), the thyroid was 'blocked' and additional scintigraphy was done with 370-555 MBq 99mTc-MIBI, 15 and 120 min.p.i. It was estimated that in all Pts there was a visualization of thyroid. In 1 of them, a large 'hot' nodule was visualized in the early and late image. Later on a differentiated thyroid carcinoma was proved histologically. In the rest of the patients 'cold' nodules with different size were visualized, eventually as a result of cysts. As a conclusion we consider, that a scintigraphy with 99mTc-MIBI is a useful tool in Pts with 'blocked' thyroid. In addition an evaluation of the thyroid nodule could be done and therefore- a recommendation for therapy

  3. 77 FR 41400 - AV Solar Ranch 1, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request...

    Science.gov (United States)

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission AV Solar Ranch 1, LLC; Supplemental Notice That Initial Market- Based Rate...-referenced proceeding of AV Solar Ranch 1, LLC's application for market-based rate authority, with an...

  4. Varumärkesvärdering : Implementeringen av IAS 38 och IFRS 3

    OpenAIRE

    Calmfors, Cecilia

    2007-01-01

    Den 1:a januari 2005 infördes nya redovisningsregler gällande företagsförvärv. Samtliga svenska börsnoterade företag skall redovisa i enlighet med IFRS 3 Företagsförvärv och IAS 38 Immateriella tillgångar. De nya reglerna innebär bland annat att varumärken och andra immateriella tillgångar skall värderas separat från goodwill i balansräkningen. Syftet med uppsatsen är att undersöka effekten av IAS 38 på svenska företags redovisning av immateriella tillgångar, med fokus på varumärken. Studien ...

  5. Övervakning av switchar och övrig nätverksutrustning

    OpenAIRE

    Björknäs, Jimmy

    2015-01-01

    Mitt examensarbete har gått ut på att förena trafikgrafer och alarmering av nätverksutrustning som inte är nåbar till samma ställe, samt underlätta processen att lägga till eller ta bort en enhet från övervakningen. Tidigare har två olika program använts för uppgifterna, vilket betyder enheterna ska läggas till på två olika ställen samt att en del enheter inte har varit möjliga att övervaka där. I arbetet jämförde jag programmen Nagios, Icinga, openNMS och Observium. Vissa av dessa program va...

  6. Optimering av nanocellulosa för tillämpning som papperstyrkeadditiv

    OpenAIRE

    Englöf, Johan

    2015-01-01

    Syftet med projektet var att undersöka hur homogeniserings förhållanden (tryck antal passager och därmed energiinsatsen) vid framställning av MFC (mikrofibrillär cellulosa), från enzymatiskt förbehandlade pappersmassafibrer påverkar hållfastheten av papper förstärkt med MFC. Arbetsgivaren för projektet var Innventia och det laborativa arbetet har utförts i deras lokaler. Fördelen med att använda MFC som tillsats i papper är att arket blir starkare [1]. Detta medför att en mindre mängd materia...

  7. In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.

    Science.gov (United States)

    Hansen, Allan K; Knudsen, Karoline; Lillethorup, Thea P; Landau, Anne M; Parbo, Peter; Fedorova, Tatyana; Audrain, Hélène; Bender, Dirk; Østergaard, Karen; Brooks, David J; Borghammer, Per

    2016-07-01

    The tau tangle ligand (18)F-AV-1451 ((18)F-T807) binds to neuromelanin in the midbrain, and may therefore be a measure of the pigmented dopaminergic neuronal count in the substantia nigra. Parkinson's disease is characterized by progressive loss of dopaminergic neurons. Extrapolation of post-mortem data predicts that a ∼30% decline of nigral dopamine neurons is necessary to cause motor symptoms in Parkinson's disease. Putamen dopamine terminal loss at disease onset most likely exceeds that of the nigral cell bodies and has been estimated to be of the order of 50-70%. We investigated the utility of (18)F-AV-1451 positron emission tomography to visualize the concentration of nigral neuromelanin in Parkinson's disease and correlated the findings to dopamine transporter density, measured by (123)I-FP-CIT single photon emission computed tomography. A total of 17 patients with idiopathic Parkinson's disease and 16 age- and sex-matched control subjects had (18)F-AV-1451 positron emission tomography using a Siemens high-resolution research tomograph. Twelve patients with Parkinson's disease also received a standardized (123)I-FP-CIT single photon emission computed tomography scan at our imaging facility. Many of the patients with Parkinson's disease displayed visually apparent decreased (18)F-AV-1451 signal in the midbrain. On quantitation, patients showed a 30% mean decrease in total nigral (18)F-AV-1451 volume of distribution compared with controls (P = 0.004), but there was an overlap of the individual ranges. We saw no significant correlation between symptom dominant side and contralateral nigral volume of distribution. There was no correlation between nigral (18)F-AV-1451 volume of distribution and age or time since diagnosis. In the subset of 12 patients, who also had a (123)I-FP-CIT scan, the mean total striatal dopamine transporter signal was decreased by 45% and the mean total (18)F-AV-1451 substantia nigra volume of distribution was decreased by 33% after

  8. Restaurang i vardagsrummet : En kvalitativ undersökning av fenomenet middagsklubbar

    OpenAIRE

    Ridderheim, Karin

    2012-01-01

    I följande studie undersöks fenomenet middagsklubbar, ett slags hemma-hos-restauranger där matglada amatörkockar bjuder in okända människor på middag i sitt hem. Syftet med studien är att undersöka vilka som lockas av att driva och besöka middagsklubbar samt varför fenomenet blir alltmer populärt i det senmoderna samhället. Materialet utgörs av kvalitativa djupintervjuer med fyra personer som själva driver middagsklubbar. Genom innehållsanalys hittades gemensamma teman, vilka sedan analyserad...

  9. Clapping hands : En analys av emojis i politisk kommunikation på Instagram

    OpenAIRE

    Junefjäll, Jonathan; Nurro, Linnéa

    2017-01-01

    Emojis är ett digitalt uttryckssätt baserade på smileys och emoticons som introducerades i smarta telefoner under 2011 och har sedan dess blivit en integrerad del av många människors vardagliga kommunikation. De används också i politisk kommunikation på sociala medier på samma sätt som en del i ett modernt uttryckssätt. Den här undersökningen tittar på 557 emojis i 300 inlägg gjorda av tre ledande politiska partier – Høyre i Norge, Socialdemokraterna i Sverige och Venstre i Danmark. Syftet är...

  10. Multifaktormodeller på den svenska marknaden - En studie av OMX Stockholm mellan 1996 och 2014

    OpenAIRE

    Hammarfrid, Peter; Henningsson, Tom

    2015-01-01

    Bakgrund:CAPM räcker i flera tillfällen inte till för att estimera framtida avkastning. Vissa av prisavvikelsernafrån CAPM är väldokumenterade och har bestått över tid, vilket har lett till uppkomsten avkorrigerande faktorer. En modell som använder sig av två sådana korrigerande faktorer är Fama ochFrenchs tre-faktormodell. Den har testats flertalet gånger på den svenska marknaden där den visat gehögre förklaringsgrader än CAPM. År 2012 samt år 2014 presenterades två nya multifaktormodeller,s...

  11. Förbättring av tjänsteleverans för konsultbolag

    OpenAIRE

    Samuelsson, Martin; Törnvall, Alexander

    2014-01-01

    Lönsamheten för konsultbolag är beroende av antalet timmar konsulter arbetar vad gäller leveranser i kunduppdrag. Att timmar ej levereras på grund av sjukdom eller överbeläggning påverkar resultatet för bolaget. Konsultbolag där konsulter samma vecka arbetar mot olika kunder och uppdrag, kan ha svårt att synliggöra och följa upp leveranserna vilket kan resultera i inkomstbortfall och försenade leveranser. Hypotesen för detta examensarbete är att visualisering och uppföljning minskar risken ti...

  12. Apoio financeiro oferecido por avós a netos adolescentes

    Directory of Open Access Journals (Sweden)

    Alessandra Ribeiro Ventura Oliveira

    2012-03-01

    Full Text Available Através de uma revisão bibliográfica sistemática da literatura analisou-se a relação entre avós e netos adolescentes com foco nas diferentes formas de apoio financeiro oferecido pelos avós. O levantamento, através das bases de dados eletrônicas MEDLINE/PubMed, LILACS e SciELO, foi concluído com  07 citações afins. Foram identificadas as relações em que o apoio financeiro assumiu papel importante na relação entre ambos os sujeitos, sugerindo compor um estilo de exercer a avosidade.   

  13. Detektion av “troll” i Twitterflöden med hjälp av klusteralgoritm : Metod för att detektera personer som sprider desinformation

    OpenAIRE

    Yousef, Andy; Lansner, Erik

    2016-01-01

    Sociala medier har alltid varit en plats där personer kan diskutera fritt om sina åsikter och dela nyheter med många. Lätt spridning av nyheter från alla hörn i världen kan komma vara användbart för att ha möjlighet att få opartiska nyheter. Även om det finns klara fördelar med exempelvis Twitter så kan det vara problematiskt med falska och uppgjorda nyheter. Ryktesspridning eller uppgjorda nyheter förekommer i stor utsträckning fortfarande, här testas metod(er) för att upptäcka vilka som kan...

  14. Pedagogiske lederes erfaringer med og forebygging av begynnende mobbeatferd i barnehagen.

    OpenAIRE

    Alfsvåg, Anna

    2017-01-01

    Master's thesis in Special education Studiens tema er barns begynnende mobbeatferd, og hvordan dette erfares og forebygges av fire pedagogiske ledere i barnehager. Teoretiske perspektiver som belyser temaets perspektiver og kompleksitet er begrepene vold eller mobbing (Isdal, Andreassen & Thilesen, 2003), mobbing i barnehagen (Falck, 2013 og Størksen, 2013), aggresjonsperspektivet (Roland, 2011 og Olweus, 1993), ulike tiltak som kan iverksettes som tidlig innsats (Tremblay, 2010), verdien ...

  15. Frihet & struktur : en kvalitativ studie av skolelivskvalitet hos ungdom med Tourette syndrom

    OpenAIRE

    Siverts, Torstein

    2005-01-01

    Sammendrag. Tittel: Skolelivskvalitet hos ungdom med Tourette Syndrom Med bakgrunn i egen erfaring fra arbeid med elever med Tourette Syndrom i grunnskolen, og i studier i spesialpedagogisk teori og empiri, etterstrebes det i denne studien å utvikle økt forståelse for hva slags erfaringer fra og perspektiver på sitt skoleliv elever med denne funksjonshemmende lidelsen har. Med grunnlag i analyser av intervjuer med elever om deres erfaringer og perspektiver, har jeg prøvd å b...

  16. Språkkartlegging av flerspråklige barn i barnehagen - fra kontrovers til kompromiss?

    Directory of Open Access Journals (Sweden)

    Nassira Essahli Vik

    2017-07-01

    Full Text Available Språkkartlegging i barnehagen er et konfliktfylt felt som preges av enten/eller tenkning. På den ene siden ser kartleggingstilhengerne ut til å ha en positivistisk tro på at kartlegging kan bidra til løsninger på alt fra enkeltbarns behov for hjelp, til tilrettelegging for livslang læring og sosial utjevning. På den andre siden ser kartleggingsskeptikerne ut til å befinne seg innenfor den nordiske barnehagemodellen, som tradisjonelt bygger på et helhetlig syn på læring og på en sterk vektlegging av barndommens egenverdi. Spenningen kan ha store konsekvenser for praksisfeltet. I denne artikkelen drøfter jeg språkkartleggingsdiskursen i lys av teori om vitenskapelige kontroverser og konkluderer med at det er åpning for kompromisser, men også at det er tendenser i diskursen som snarere kan forsterke enn redusere uenigheten om språkkartlegging av flerspråklige barn i barnehagen. Mapping of language skills in early childhood education and care (ECEC institutions is controversial. On the one hand, there are those who support language mapping based on a belief that mapping and measuring can help language acquisition and facilitate lifelong learning and social integration. On the other hand, there are skeptics who oppose mapping and emphasize the values of childhood. This article discusses the discourses on language mapping in light of theories on scientific controversies. Based on the analysis I find that although there are openings for compromises, it seems that tendencies in the discourse may amplify rather than reduce the controversy on the language mapping of multilingual children in Norwegian ECEC institutions.

  17. A.V. Usova's Contribution to the Field of Concept Learning in Physics Classroom

    Science.gov (United States)

    Yavoruk, Oleg

    2015-01-01

    A.V. Usova (1921-2014) has always been one of the leading figures in Russian physics education. Her theory of physics concept formation was formulated during the 1970s and the 1980s and directly influenced the process of physics education in the 20th and the 21st century. Over the years there have been a lot of theories of concept formation. Her…

  18. Kjemiske og biokjemiske studier av den maliske medisinplanten Terminalia macroptera : Etnofarmakologiske studier i Mali

    OpenAIRE

    Pham, Anh Thu

    2009-01-01

    Blader fra den vest-afrikanske planten Terminalia macroptera ble ekstrahert suksessivt med diklormetan og metanol. Disse utgjorde råekstraktene, som var utgangspunkt for videre separasjon og fraksjonering ved hjelp av væske-væske ekstraksjon, kolonnekromatografi og tynnsjiktskromatografi. De isolerte forbindelsene ble strukturoppklart ved 1H-, 13C-, APT- og COSY NMR-spektroskopi. Shikimisyre, flavonoidglykosidene rutin og narcissin, og ellagitanninet corilagin ble isolert fra butanol-fasen...

  19. Med sjefen på Facebook: En studie av ledere som er "venner" med sine ansatte

    OpenAIRE

    Jensen, Anita

    2014-01-01

    MR690 Masteroppgave i organisasjon og ledelse - utdanningsledelse Formålet med studien er å belyse hvordan aktiv bruk av sosiale medier, i dette tilfellet Facebook, påvirker relasjoner mellom mennesker. Hva skjer når en tar i bruk en websjanger som i utgangspunktet er umiddelbar og uformell, til jobbrelatert og mer formell kommunikasjon? Er det sjangeren eller relasjonen som endres? Søkelyset rettes mot ledere som er “venner” med sine medarbeidere, og problemstillingen er...

  20. Performance comparison of AV1, HEVC, and JVET video codecs on 360 (spherical) video

    Science.gov (United States)

    Topiwala, Pankaj; Dai, Wei; Krishnan, Madhu; Abbas, Adeel; Doshi, Sandeep; Newman, David

    2017-09-01

    This paper compares the coding efficiency performance on 360 videos, of three software codecs: (a) AV1 video codec from the Alliance for Open Media (AOM); (b) the HEVC Reference Software HM; and (c) the JVET JEM Reference SW. Note that 360 video is especially challenging content, in that one codes full res globally, but typically looks locally (in a viewport), which magnifies errors. These are tested in two different projection formats ERP and RSP, to check consistency. Performance is tabulated for 1-pass encoding on two fronts: (1) objective performance based on end-to-end (E2E) metrics such as SPSNR-NN, and WS-PSNR, currently developed in the JVET committee; and (2) informal subjective assessment of static viewports. Constant quality encoding is performed with all the three codecs for an unbiased comparison of the core coding tools. Our general conclusion is that under constant quality coding, AV1 underperforms HEVC, which underperforms JVET. We also test with rate control, where AV1 currently underperforms the open source X265 HEVC codec. Objective and visual evidence is provided.