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Sample records for aux roses cea

  1. Report of transparency and nuclear safety 2007 CEA Fontenay aux Roses; Rapport transparence et securite nucleaire 2007 CEA Fontenay aux Roses

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Fontenay aux roses for the year 2007. After many years of decommissioning and dismantling of nuclear installations, the Center is now devoted (since 2005) to the development of research programmes on biology and biomedical technologies. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. (A.L.B.)

  2. Decommissioning of the Nuclear Licensed Facilities at the Fontenay aux Roses CEA Center

    International Nuclear Information System (INIS)

    Jeanjacques, Michel; Piketty, Laurence; Mandard, Lionel; Pedron, Guy; Boissonneau, Jean Francois; Fouquereau, Alain; Pichereau, Eric; Lethuaire, Nathalie; Estivie, David; Binet, Cedric; Meden, Igor

    2008-01-01

    This is a summary of the program for the decommissioning of all the CEA's facilities in Fontenay aux Roses. The particularity of this center is that it is located in a built-up area. Taking into account the particularities of the various buildings and the levels of radioactivity in them, it was possible to devise a coherent, optimized program for the CEA-FAR licensed nuclear facility decommissioning operations

  3. Decommissioning of the nuclear licensed facilities at the Fontenay aux Roses CEA center

    International Nuclear Information System (INIS)

    Jeanjacques, Michel; Piketty, Laurence; Letuhaire, Nathalie; Mandard, Lionel; Meden, Igor; Estivie, David; Boissonneau, Jean Francois; Fouquereau, Alain; Pichereau, Eric; Binet, Cedric

    2007-01-01

    Available in abstract form only. Full text of publication follows: The French Atomic Energy Commission (CEA) center at Fontenay aux Roses (CEN-FAR) is the Commission's oldest center is located in the southern suburbs of Paris. It was opened on 26 March 1946 to host the first French nuclear reactor ZOE that went critical on 12 December 1946. The first laboratories were installed in existing buildings on the site. (authors)

  4. Report of transparency and nuclear safety 2007 CEA Fontenay aux Roses

    International Nuclear Information System (INIS)

    2007-01-01

    This report presents the activities of the CEA Center of Fontenay aux roses for the year 2007. After many years of decommissioning and dismantling of nuclear installations, the Center is now devoted (since 2005) to the development of research programmes on biology and biomedical technologies. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. (A.L.B.)

  5. Evaluation of the radiology state at the CEA/Fontenay-aux-Roses and its environment

    International Nuclear Information System (INIS)

    2000-10-01

    Since 1946 the nuclear installations followed one other at the CEA of Fontenay-aux-Roses still their gradual stop the last ten years, except two installations INB34 and INB73, necessary for the wastes management. Today these installations form the subject of a drainage program. The public opinion is regularly informed on this program since 1999. This document presents the stock of the actions realized since this date: the track keeping of the sites activities impacts on the environment and the actions realized since 1999. (A.L.B.)

  6. EMC: a new equipment for repackaging the ancient waste from Fontenay-aux-Roses CEA site

    International Nuclear Information System (INIS)

    Ithurbide, A.; Masy, J.C.; Serrano, R.; Blanc, S.

    2017-01-01

    A new equipment called EMC (Equipment for measuring and packaging) is being built on the Fontenay-aux Roses site in the framework of the cleaning-up of this CEA site. Studies on irradiated fuels and on radio-chemical processes were performed till 1995 and a large quantity of radioactive waste were generated and have stayed on the site so far in storage pits. EMC purpose is to prepare high level radioactive waste for their removal towards the Diadem storing facility that is being built on the Marcoule CEA site. EMC will deal with α-emitter contaminated waste and will be able to recover ancient 50 l waste drums from storage pits, to characterize their radioactive content, to open them, to package them in CDD1 drum (each CDD1 drum can contain up to 5 ancient drums), and to load CDD1 drums in transport packing. EMC is expected to operate for 4 years. (A.C.)

  7. Decommissioning works are going on at Fontenay-aux-roses CEA center

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    The CEA center of Fontenay-aux-roses is pursuing the dismantling operations of its nuclear installations. In 2003 120 glove boxes of the plutonium chemistry laboratory were disassembled and moved to the Cadarache CEA center. Hot cells from the Castor, Cyrano and Petrus lines are currently undergoing decontamination operations before being dismantled. As for the processing station of liquid effluents, the cutting works of the incinerator of low-level radioactive wastes and of the tanks began in 2003 and are expected to be over by end 2004. The Triton research reactor was decommissioned in 1982 and dismantling works on its hot cell and on its pool began at the end of 2003. (A.C.)

  8. Report on nuclear safety and transparency 2011 - Fontenay-aux-Roses CEA centre

    International Nuclear Information System (INIS)

    2012-06-01

    After a brief presentation of the Fontenay-aux-Roses CEA centre, this report indicates the different safety measures in the different nuclear base installations (INB) of this site (measures related to different risks, to emergency situations, to inspections and audits). It describes measures related to radiation protection: organisation, dosimetry results. It presents the different significant events which occurred in 2011 and were declared to the ASN. It discusses the results of measurements of liquid, gaseous and chemical releases from the installations and their impact on the environment. It addresses the radioactive waste management (measures to limit their volume and to limit their impact on health and on the environment, notably on water and soils, type and quantities of wastes stored in INBs). It presents the different measures and actions related to information transparency

  9. Report on transparency and nuclear safety 2015 - Fontenay-aux-Roses CEA centre

    International Nuclear Information System (INIS)

    2016-06-01

    This document proposes, first, a presentation of the Fontenay-aux-Roses CEA centre, of its activities and installations. Then it gives a rather detailed overview of measures related to safety and to radiation protection within these activities and installations. Next, it reports significant events related to safety and to radiation protection which occurred in 2015 and which have been declared to the French nuclear safety authority (ASN). It discusses the results of release measurements (liquid and gaseous effluents, radiological assessment, and chemical assessment for various installations) and the control of the chemical and radiological impact of these gaseous and liquid effluents on the environment. Finally, it addresses the issue of radioactive wastes which are stored in the different nuclear base installations of the Centre. It indicates the different measures aimed at limiting the volume of these warehoused wastes and addresses their impact on health and environment. Nature and quantities of warehoused wastes are specified. Remarks and recommendations of the Health, Safety and Working Conditions Committee (CHSCT) are given

  10. Report on transparency and nuclear safety - Fontenay-aux-Roses CEA centre - 2012

    International Nuclear Information System (INIS)

    2013-01-01

    This report presents the different nuclear base installations (INB) of the Fontenay-aux-Roses CEA centre, gives an overview of measures regarding safety within these installations (organisation, general arrangements, arrangements related to different risks, defence in-depth, management of emergency situations, inspections, audits and second-level controls, arrangements and main events specific to the different installations and buildings, issues related to transports, soil radiological assessment) and measures related to radiation protection (organisation and results). It reports the significant events related to safety and radiation protection which occurred in 2012 and were declared to the ASN, and discusses how the return-on-experience has been used. It reports and comments the results of measurements of radiological and chemical gaseous and liquid effluents, of surveys of the environment. It also evokes important events related to these measurement and survey processes, presents the environmental management approach. The next part addresses the management of radioactive wastes: arrangements aimed at limiting the volume of warehoused wastes, and at limiting their impact on health and on the environment, nature and quantities of warehoused wastes. The different arrangements regarding transparency and information are reviewed (TSN report, newsletter, and so on)

  11. Application of the New Decommissioning Regulation to the Nuclear Licensed Facilities (NLF) at Fontenay-aux-Roses's Nuclear Center (CEA)

    International Nuclear Information System (INIS)

    Sauret, Josiane; Piketty, Laurence; Jeanjacques, Michel

    2008-01-01

    This abstract describes the application of the new decommissioning regulation on all Nuclear Licensed Facilities (NLF is to say INB in French) at Fontenay-aux-Roses's Center (CEA/FAR). The decommissioning process has been applied in six buildings which are out of the new nuclear perimeter proposed (buildings no 7, no 40, no 94, no 39, no 52/1 and no 32) and three buildings have been reorganized (no 54, no 91 and no 53 instead of no 40 and no 94) in order to increase the space for temporary nuclear waste disposal and to reduce the internal transports of nuclear waste on the site. The advantages are the safety and radioprotection improvements and a lower operating cost. A global safety file was written in 2002 and 2003 and was sent to the French Nuclear Authority on November 2003. The list of documents required is given in the paragraph I of this paper. The main goals were two ministerial decrees (one decree for each NLF) getting the authorization to modify the NLF perimeter and to carry out cleaning and dismantling activities leading to the whole decommissioning of all NLF. Some specific authorizations were necessary to carry out the dismantling program during the decommissioning procedure. They were delivered by the French Nuclear Safety Authority (FNSA) or with limited delegation by the General Executive Director (GED) on the CEA Fontenay-aux-Roses's Center, called internal authorization. Some partial dismantling or decontamination examples are given below: - evaporator for the radioactive liquid waste treatment station (building no 53): FNSA authorization: phase realised in 2002/2003. - disposal tanks for the radioactive liquid waste treatment station (building no 53) FNSA authorization: phase realised in 2004, - incinerator for the radioactive solid waste treatment station (building no 07): FNSA authorization: operation realised in 2004, - research equipments in the building no. 54 and building no. 91: internal authorization ; realised in 2005, - sample

  12. Preliminary dismantling for the decommissioning of nuclear licensed facilities at the CEA Centre in Fontenay aux Roses

    International Nuclear Information System (INIS)

    Estivie, D.; Bohar, M.P.; Jeanjacques, M.; Binet, C.

    2008-01-01

    Under the perimeter modification programme for the Nuclear Licensed Facilities (NLFs) of the French Atomic Energy Commission centre at Fontenay aux Roses (CEN-FAR), preliminary dismantling work proved necessary to decommission the buildings outside the nuclear perimeter and create interim storage areas for waste packages. This summary describes the dismantling of Buildings 07, 53 and 91/54, which are the most representative of the preliminary dismantling work. (author)

  13. Decommissioning of the nuclear licensed facilities at the Fontenay aux Roses CEA Center; cleanup of nuclear licensed facility 57 and monitoring of operations and operating feedback

    International Nuclear Information System (INIS)

    Estivie, D.; Bohar, M.P.; Jeanjacques, M.; Binet, C.; Bremond, M.P.; Poyau, C.; Mandard, L.; Boissonneau, J.F.; Fouquereau, A.; Pichereau, E.

    2008-01-01

    This is a summary of the program for the decommissioning of all the CEA Licensed Nuclear Facilities in Fontenay aux Roses. The particularity of this center is now it is located in a built-up area. It is presented like example the operations to clean up the equipment of the Nuclear Licensed Facility 57 (NLF 57). Due to the diversity of the research and development work carried out on the reprocessing of spent fuel in it, this installation is emblematic of many of the technical and organizational issues liable to be encountered in the final closure of nuclear facilities. It was developed a method applied to establish the multi-annual budget, monitor the progress of operations and integrate, as work continues, the operating feedback. (author)

  14. The Tokomak of Fontenay-aux-Roses

    International Nuclear Information System (INIS)

    Ginot, P.; Torossian, A.

    1975-01-01

    The Tokomak of Fontenay-aux-Roses (TFR) has been built in order to increase the performances got with the same type of machine by the Soviet physicists. The current induced into the plasma has reached 0.4MA, the main magnetic field being 60kG. A plasma with a mean electron density of 4.5 10 13 cm -3 , a maximum electron temperature of 2.5keV and a maximum ion temperature of 1keV has been obtained in hydrogen and deuterium. The discharge duration has attained 0.5sec. These results agree with those obtained before [fr

  15. Second meeting of the Atomic and Molecular Data Centre network. Fontenay aux Roses, 23-24 May 1980

    International Nuclear Information System (INIS)

    Katsonis, K.

    1980-11-01

    Summary report of the Second A+M Data Centre Network (DCN) meeting convened by the IAEA Nuclear Data Section at the CEA Laboratory at Fontenay-aux-Roses, France, 23-24 May 1980. The meeting was attended by 20 representatives from centres and groups from six Member States concerned with the coordinated international management of atomic and molecular data pertinent to controlled fusion research and technology

  16. Results from the Tokamak Fontenay-aux-Roses

    International Nuclear Information System (INIS)

    Ginot, P.

    1975-01-01

    It became clear in 1969 that confinement and heating in Tokomaks offered great possibilities and the Fontenay-aux-Roses Tokamak (TFR) was built for research on their improved efficiency. A plasma of mean density 4.5.10 13 cm -3 and of maximum electron and ion temperatures 2.5 and 1 keV respectively was obtained. The current induced in the gas reached 0.4MA and discharges were maintained for more than 0.5s. The ion assembly seems to behave according to the mechanism predicted by theory, that of electrons suffers an abnormal energy loss. These results confirm and add to those obtained earlier. The machine is now being used for the detailed study of an energy balance and of the most plausible loss mechanisms (turbulence, impurities) and for the development of new heating methods [fr

  17. Neutron distribution in the central cell and a peripheral cell of the Fontenay-aux-Roses pile

    International Nuclear Information System (INIS)

    Roullier, F.

    1958-01-01

    The distribution of the neutron density has been determined in the central cell and a peripheral cell of the pile at Fontenay-aux-Roses. This measurement was carried out by the autoradiographic method with manganese detectors. The neutron density distribution in the uranium rod has already been studied. The measurement was completed by the study of the neutron density in the complete cell by means of detectors placed in the uranium and in the heavy water. (author) [fr

  18. Order of 30 March 1988 on licensing of gaseous radioactive effluent releases by the Fontenay-aux-Roses Nuclear Research Centre

    International Nuclear Information System (INIS)

    1988-01-01

    This Decree prescribes the documents and information the Fontenay-aux-Roses Nuclear Research Centre must provide to the Central Service for Protection against Ionizing Radiation (SCPRI) and lays down the permissible effluent release limits for the Centre [fr

  19. Contribution to the study of several chemical hazards in the Centre d'Etudes Nucleaires of Fontenay-aux-Roses; Contribution a l'etude de quelques nuisances chimiques au centre d'etudes nucleaires de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Megemont, C; Grau, C [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-10-01

    From the checking of 2750 index cards of hazards, the study relates the distribution of the chemical hazards in the Centre d'Etudes Nucleaires of Fontenay-aux-Roses. Those concerning the greatest number of agents in the Centre are classified according to the categories corresponding to the different conditions of working. Thus, the most important are put forward. Then, the authors rapidly make a review of hazards which may have some special interest because they appear more specific of the nuclear energy or because they are the most frequently noted on the index cards of hazards. The case of the tributylphosphate is studied more precisely. (authors) [French] A partir de l'examen de 2750 fiches de nuisances, l'etude porte sur la repartition des nuisances chimiques au Centre d'Etudes Nucleaires de Fontenay-aux-Roses. Celles qui concernent le plus grand nombre d'agents du Centre sont classees selon les categories correspondant aux differentes conditions de travail. Les plus importantes d'entre elles sont ainsi mises en evidence. | Les auteurs passent ensuite en revue, rapidement, les nuisances qui peuvent presenter un interet particulier soit parce qu'elles semblent plus specifiques de l'Energie Nucleaire, soit parce qu'on les rencontre le plus frequemment sur les fiches de nuisances. Le cas du tributylphosphate est envisage de facon plus detaillee. (auteurs)

  20. Recapitulative list of the C.E.A. reports published by the French Atomic Energy Commission (n.757-1062, december 1957-december 1958) supplement to C.E.A. reports n. 593 and 756; Liste recapitulative des rapports C.E.A. publies par le Commissariat a l'Energie Atomique (du n.757 a 1062, decembre 1957-decembre 1958) complement aux rapports C.E.A. n. 593 et 756

    Energy Technology Data Exchange (ETDEWEB)

    Schmiterlow, C G; Cohen, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Recapitulative list of the C.E.A. reports published by the French Atomic Energy Commission. (number 757-1062, december 1957 - december 1958). Supplement to C.E.A. reports number 593 and 756. (author) [French] Liste recapitulative des rapports C.E.A. publies par le Commissariat a l'Energie Atomique (du numero 757 au numero 1062, decembre 1957 - decembre 1958). Complement aux rapports C.E.A. numero 593 et 756. (auteur)

  1. Annual progress report of the Fontenay-aux-Roses Research Group. January 1 to December 31 1977

    International Nuclear Information System (INIS)

    1977 at Fontenay-aux-Roses was dominated by the assembly and starting up of TFR 600, whereas at Grenoble it coincided with a period of full scientific production on Petula and Wega. On TFR 600 a study was made on discharges in the absence of a conducting shell and on plasma purity. Tokamak physics covered the analysis of the mechanism of disruptions and the dynamics of impurities on TFR 400, and the neutral injection (circular periplasmatron). Simultaneously the heating experiments and the diagnostics for TFR 600 were actively prepared, as well as the Torre II project [fr

  2. Neutron distribution in the central cell and a peripheral cell of the Fontenay-aux-Roses pile; Repartition des neutrons dans la cellule centrale et une cellule peripherique de la pile de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Roullier, F [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1958-07-01

    The distribution of the neutron density has been determined in the central cell and a peripheral cell of the pile at Fontenay-aux-Roses. This measurement was carried out by the autoradiographic method with manganese detectors. The neutron density distribution in the uranium rod has already been studied. The measurement was completed by the study of the neutron density in the complete cell by means of detectors placed in the uranium and in the heavy water. (author) [French] La repartition de la densite des neutrons a ete determinee dans la cellule centrale et une cellule peripherique de la pile de Fontenay-aux-Roses. Cette mesure a ete effectuee par la methode d'autoradiographie avec des detecteurs de manganese. La repartition de la densite des neutrons dans la barre d'uranium a deja ete etudiee. La mesure a ete completee par l'etude de la densite des neutrons dans la cellule complete a l'aide de detecteurs places dans l'uranium et dans l'eau lourde. (auteur)

  3. Health physics around a controlled fusion research device: the Tokamak at Fontenay-aux-Roses (T.F.R.)

    International Nuclear Information System (INIS)

    1977-01-01

    The X and neutron dosimetry measurement near the magnetic confinement device for hot plasma, called T.F.R. (Tokamak, Fontenay-aux-Roses) are presented. The biological shielding consists of an ordinary concrete wall 30 cm thick; the dose rate is thus limited at 10 -1 mrem per discharge (corresponding to 10 mrem per day) in the whole area frequented by people during T.F.R. operation. A numerical calculation, taking into account the true geometry and X ray reflexion by the walls and roof, and normalized to the measurements, gives some indications on the electron beam which produces X rays. The photoneutron source (up to 10 10 neutrons per dischage) and the activation of the vacuum vessel result from high energy electrons (>= 10 MeV) supporting a 10 to 1,000 A current [fr

  4. Purification and final concentration of the plutonium obtained by treatment of irradiated uranium at the Fontenay-aux-Roses pilot plant; Purification et concentration finales du plutonium en fin de traitement de l'uranium irradie a l'usine-pilote de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Prevot, I; Corpel, J; Regnaut, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    This paper consists of: 1- a recapitulation of the laboratory tests which led to the choice of the method; 2- a description of the latter, with the results obtained at the Fontenay-aux-Roses pilot plant; 3- the analytical methods used for checking and verifying the purity of the plutonium. (author)Fren. [French] Cet expose comprend: 1- le rappel des essais de laboratoire qui ont conduit au choix du procede; 2- la description de ce dernier, avec les resultats obtenus a l'Usine-Pilote de Fontenay-aux-Roses; 3- les methodes analytiques utilisees pour le controle et pour la verification de la purete du plutonium. (auteur)

  5. Transcriptome profiling of petal abscission zone and functional analysis of an Aux/IAA family gene RhIAA16 involved in petal shedding in rose

    Directory of Open Access Journals (Sweden)

    Yuerong Gao

    2016-09-01

    Full Text Available Roses are one of the most important cut flowers among ornamental plants. Rose flower longevity is largely dependent on the timing of petal shedding occurrence. To understand the molecular mechanism underlying petal abscission in rose, we performed transcriptome profiling of the petal abscission zone during petal shedding using Illumina technology. We identified a total of 2592 differentially transcribed genes (DTGs during rose petal shedding. Gene ontology term enrichment and pathway analysis revealed that major biochemical pathways the DTGs were involved in included ethylene biosynthesis, starch degradation, superpathway of cytosolic glycolysis, pyruvate dehydrogenase and TCA cycle, photorespiration and the lactose degradation III pathway. This suggests that alterations in carbon metabolism are an important part of rose petal abscission. Among these DTGs, approximately 150 genes putatively encoding transcription factors were identified in rose abscission zone. These included zinc finger, WRKY, ERF, and Aux/IAA gene families, suggesting that petal abscission involves complex transcriptional reprogramming. Approximately 108 DTGs were related to hormone pathways, of which auxin and ethylene related DTGs were the largest groups including 52 and 41 genes, respectively. These also included 12 DTGs related to gibberellin and 6 DTGs in jasmonic acid pathway. Surprisingly, no DTGs involved in the biosynthesis/signaling of abscisic acid, cytokinin, brassinosteroid, and salicylic acid pathways were detected. Moreover, among DTGs related to auxin, we identified an Aux/IAA gene RhIAA16 that was up-regulated in response to petal shedding. Down-regulation of RhIAA16 by virus-induced gene silencing in rose promoted petal abscission, suggesting that RhIAA16 plays an important role in rose petal abscission.

  6. Annual progress report of the Fontenay-aux-Roses Research Group, January 1 to December 31 1974

    International Nuclear Information System (INIS)

    The salient events of 1974 were the full-time working of TFR at Fontenay-aux-Roses and the building of Petula and Wega at Grenoble. The remounting of TFR after reinforcement of the vacuum chamber was followed by an increase in the small plasma radius by elimination of the copper shell to prolong the present program. In agreement with the Culham laboratory a common program to develop the injection of neutral particles up to the performance needed for the JET has begun. At Grenoble the mounting of Petula was finished and the technological problems of the vacuum chamber (metallic joints for the alumina-metal joints) have been solved. The mounting of Wega was pursued simultaneously with that of Petula within the European context of a collaboration with Garching and the Royal Military School. In the ''Ionized Gas Theory Section'' work was centered on: M.H.D. equilibrium and stability, plasma development in Tokamaks, waves, transport and convection, spectroscopy, micro-instabilities and turbulence. Fundamental physics covers the subjects: EQUATOR, EOS-POP and ODE experiments, HCN laser and atomic collisions. The activity in open configuration concerned the experiment Bille-en-Tete MB [fr

  7. The treatment of irradiated uranium fuel. Results obtained while operating the pilot plant at Fontenay-aux-Roses; Le traitement de l'uranium irradie. Resultats d'exploitation de l'usine-pilote de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Regnaut, P; Faugeras, P; Brut, A; Helou, R; Redon, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    In this paper the results obtained from four years operation of the pilot plant when using bars of increasing activity, are summarised and compared with the results of parallel studies carried out in the laboratory. As a conclusion to the article, the optimum conditions for the different phases of a process based on solvent extraction are given. (author)Fren. [French] Cette conference resume les resultats obtenus durant quatre annees de fonctionnement de l'Usine-Pilote, avec des barreaux d'activite croissante et les compare aux resultats d'etudes conduites parallelement en laboratoire. En conclusion sont donnees les conditions optima pour les differentes phases d'un procede base sur l'extraction par solvant. (auteur)

  8. Dismantling and waste management: CEA's strategy and research programs

    International Nuclear Information System (INIS)

    Behar, C.

    2012-01-01

    There are 3 main dismantling operations in CEA. First, the dismantling of the UP1 facility in the Marcoule site. UP1 was a reprocessing plant of nuclear fuels that operated from 1958 to 1997 and is now the biggest dismantling operation in the world. Its dismantling operation follows a 6-step scheme that will end in 2050. Secondly, the Passage project on the Grenoble site that concerns the dismantling of 3 research reactors (Siloette, Melusine and Siloe), of a laboratory dedicated to the analysis of active materials (Lama) and of a station for the processing of waste (Sted). Thirdly the Aladin project that concerns the installations of the Fontenay-aux-Roses site. The dismantling operations are complex because all the first research programs on high activity chemistry and on transuranium elements were performed in Fontenay-aux-Roses facilities and because ancient activities have to leave a clean place to be replaced by new ones. The radioactive waste produced by CEA enter the flow of waste that is normally processed and managed by ANDRA. Only high-activities waste have not yet a definitive solution, they are stored in waiting the opening of a geological repository. CEA leads research programs on the separation and transmutation of minor actinides and on the long-term behaviour of waste packages put in deep geological layers. (A.C.)

  9. The dismantling of CEA nuclear installations

    International Nuclear Information System (INIS)

    Piketty, Laurence

    2016-03-01

    After having indicated locations of French nuclear installations which are currently being dismantled (about 30 installations), and recalled the different categories of radioactive wastes with respect to their activity level and the associated storage options, this article gives an overview of various aspects of dismantling, more precisely in the case of installations owned and managed by the CEA. These operations comprise the dismantling itself, the recovery and packaging of wastes, old effluents and spent fuels. The organisation and responsible departments within the CEA are presented, and the author outlines some operational problematic issues met due to the age of installations (traceability of activities, regulation evolutions). The issue of financing is then discussed, and its uncertainties are outlined. The dismantling strategy within the CEA-DEN is described, with reference to legal and regulatory frameworks. The next parts of the article address the organisation and the economic impact of these decontamination and dismantling activities within the CEA-DEN, highlight how R and D and advanced technology are a support to this activities as R and D actions address all scientific and technical fields of nuclear decontamination and dismantling. An overview of three important dismantling works is proposed: Fontenay-aux-Roses, the Marcoule CEA centre (a reference centre in the field of nuclear dismantling and decontamination) and the Grenoble CEA centre (reconversion in R and D activities in the fields of technologies of information, of communication, technologies, for health, and in renewable energies). The last part addresses the participation to the Strategic Committee of the Nuclear Sector (CSFN)

  10. Actinides exposure: review of Ca-DTPA injections inside Cea-Cogema plants; Exposition aux actinides: bilan des injections de Ca-DTPA dans les centres CEA-Cogema

    Energy Technology Data Exchange (ETDEWEB)

    Grappin, L.; Berard, P.; Beau, P.; Carbone, L.; Castagnet, X.; Courtay, C.; Le Goff, J.P.; Menetrier, F.; Neron, M.; Piechowski, J. [CEA Cadarache, Dir. de l' Energie Nucleaire, Dept. de Soutien en surete et securite, Sev. de Sante au Travail, 13 - Saint-Paul-lez-Durance (France)

    2006-07-01

    Ca-DTPA has been used for medical treatment of plutonium and americium contaminations in the CEA and COGEMA plants from 1970 to 2003. This report is a survey of the injections administered of Ca-DTPA as a chelating molecule. This report will be a part of the AMM process for Ca-DTPA by intravenous administration submitted by the Central Pharmacy of the french Army. Out of 1158 injections administered to 469 persons, 548 events of possible or confirmed contaminations were reported. These employees were followed by occupational physicians according to the current regulations. The first part of the report is a synthesis of the most recent findings. Due to its short biological period and its limited action in the blood, Ca-DTPA does not chelate with plutonium and americium as soon as these elements are deposited in the target organs. It justifies an early treatment, even in cases of suspected contamination followed by additional injections if necessary. The second part presents data concerning these 1158 injections (way of contamination, posology, adverse effects...). These incidents took place at work, were most often minor, not requiring follow-up treatment. A study concerning the effectiveness of the product was done on a group of people having received 5 or more injections. These results were compared with effectiveness estimated from theoretical basis. Posologies and therapeutic schemes were proposed based on these observations. Additional studies are needed to confirm these findings. This document is the first synthesis in this field. It is the result of a collective work having mobilized the occupational medicine departments, the laboratories of CEA and COGEMA and a working group CEA-COGEMA-SPRA. (authors)

  11. Dismantling at the CEA's Nuclear Energy Division: strategy and programmes

    International Nuclear Information System (INIS)

    Lecomte, C.; Prunele, D. de; Rozain, J.P.; Nokhamzon, J.G.; Tallec, M.

    2008-01-01

    The CEA's Nuclear Energy Division (DEN) nuclear facilities currently include seventeen reactors and thirty six other miscellaneous facilities, particularly laboratories, fuel processing units and facilities specific to waste management. Some of these are currently being dismantled or must be dismantled soon so that the DEN, the Nuclear Energy Division, can construct new equipment and thus have available a range of R and D facilities in line with the issues of the nuclear industry of the future. At CEA, the first nuclear facility dismantling operations go back several dozen years and involve numerous and varied facilities. The first operations of any significance took place in the 1960's and 1970's and covered, for example, the first plutonium plant at Fontenay-aux-Roses (total dismantling) and small research reactors or critical models - CESAR and PEGGY at Cadarache and MINERVE at Fontenay-aux Roses (civil engineering cleaned up and kept). At La Hague, the dismantling of AT1, a pilot workshop used by the CEA during the 1970's to process irradiated fuels from fast neutron reactors, was completed in March 2001 (IAEA former stage 3, excluding civil engineering demolition). On the other hand, during this period of first dismantling, the intermediate-sized reactors (G1, Rapsodie) were only partially dismantled after shut down, mainly due to the lack of graphite and sodium waste management routes at the time. About twenty facilities were thus dealt with up to 2001, in other words about half of all the nuclear facilities shut down permanently before this date. (authors)

  12. CEA nuclear energy Directorate - Activity report 2012

    International Nuclear Information System (INIS)

    2013-01-01

    After an overview of the activities of the Directorate at the international level, of its scientific activities, and of the consideration given to quality, and a presentation of the transverse program on advanced materials, this report proposes presentations of activities in different domains: future nuclear industrial systems (reactors of 4. generation, back-end of the future cycle, sustainable management of nuclear materials, fundamental scientific and technological research), optimization of the present industrial nuclear activity (reactors of 2. and 3. generation, front-end and back-end of the fuel cycle), the main tools for nuclear development (numerical simulation, the Jules Horowitz reactor), valorisation, economic support of Haute-Marne and Meuse territories (the Syndiese project), nuclear dismantling and decontamination (dismantling projects, projects and works in Fontenay-aux-Roses, Grenoble and Saclay, waste and material flow management, nuclear service facilities, transports). It also presents the activities of some specific CEA centres like Marcoule (R and D in fuel cycle), Cadarache (future energies) and Saclay (nuclear sciences and simulation of reactors and fuel cycle)

  13. The dismantling of nuclear installations in the Grenoble CEA centre - Press book 2013

    International Nuclear Information System (INIS)

    Laveissiere, Stephane; Coronini, Vincent

    2013-01-01

    After having outlined the importance of the project for the Grenoble CEA centre, this document presents the objectives, issues and challenges of dismantling activities performed on various nuclear installations located in the CEA centre of Grenoble. Objectives are presented in terms of agenda, predicted production of radioactive wastes, budget, personnel and steering committee. The various nuclear installations are presented: experimental reactors (Melusine, Siloe, Siloette), LAMA (laboratory of analysis of active materials), STED (station for the treatment of effluents and wastes). The safety and protection of workers is addressed in terms of protection and monitoring measures, and of exposure to radiations. The next part deals with the monitoring of the environment (actors, history of control of the centre's releases, control points, releases, atmosphere monitoring, and hydrological monitoring). A second part presents the global strategy of the CEA for its activities of sanitation and nuclear dismantling: present operations, dismantling activities in Fontenay-aux-Roses and in Marcoule, economic organization, contribution of advanced technology in radiological measurement and control, simulation and modelling, decontamination techniques, cutting operations, and remotely controlled operations

  14. Incineration as a radioactive waste volume reduction process for CEA nuclear centers

    International Nuclear Information System (INIS)

    Atabek, R.; Chaudon, L.

    1994-01-01

    Incineration processes represent a promising solution for waste volume reduction, and will be increasingly used in the future. The features and performance specifications of low-level waste incinerators with capacities ranging from 10 to 20 kg - h -1 at the Fontenay-aux-Roses, Grenoble and Cadarache nuclear centers in France are briefly reviewed. More extensive knowledge of low-level wastes produced in facilities operated by the Commissariat a l'Energie Atomique (CEA) has allowed us to assess the volume reduction obtained by processing combustible waste in existing incinerators. Research and development work is in progress to improve management procedures for higher-level waste and to build facilities capable of incinerating α - contaminated waste. (authors). 6 refs., 5 figs., 1 tab

  15. Ships & Roses

    DEFF Research Database (Denmark)

    Jensen, Thomas; Vatrapu, Ravi

    2015-01-01

    International trade involves crossing several organizational boundaries. This revelatory case study follows fresh cut roses’ journey from the growers in Kenya to the retail distribution in Holland and shows relatively high barriers related to the associated activities, information and documents...... be useful for the actors’ collaboration in the trade lane of the roses. We discuss some of the benefits of our proposed approach (e.g. lower transaction cost and real time information) but also raise some concerns (e.g. about trust and governance) which calls for further research....

  16. A Trail of Roses

    DEFF Research Database (Denmark)

    Ørum, Tania

    2015-01-01

    Heissenbüttel and Max Bense. The Danish poet and critic Hans-Jørgen Nielsen Nielsen used Gertrude Stein as a prominent example in his campaign to widen the conception of literary texts in the conservative Danish context. In one of his essays he used Stein’s sentence: a rose is a rose is a rose is a rose...

  17. The great Cea actors

    International Nuclear Information System (INIS)

    Frejacques, C.

    1997-01-01

    With the Claude Frejacques life it is a Cea passage that we find. He began the studies on uranium isotope separation. He developed and saw to a successful conclusion these researches at Cea during twenty five years and extended his sphere of operations to the whole fuel cycle, from upstream to downstream. Director of research at the Cea, he was also D.G.R.S.T. director and during eight years President of the C.N.R.S. (N.C.)

  18. Disruption Rose Tinted II

    OpenAIRE

    Livingstone, Andrew

    2009-01-01

    'Disruption - Rose Tinted II' continues to engage narratives of historical English china as previously explored in the work 'Rose Tinted'. This work engages the sleepy rural idyll which is overlaid with visual contemporary social commentary.

  19. CEA Annual report 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The CEA, a prominent player in research development and innovation, is active in three main domains: energy, health care and information technology, defense and security. This annual report presents the CEA activities for the year 2007 in these three main areas: science and technology working for nuclear deterrence and global security, the energies without greenhouse effect gases emission against the climatic change, researches in the information sciences and technologies for a better communication and health. The CEA safety, organization, communication and international relations are also presented. (A.L.B.)

  20. CEA financial report 2007

    International Nuclear Information System (INIS)

    2007-01-01

    This document provides financial data on the CEA for the year 2007. The management report (budget, resources, expenditures) and the accounting are detailed. The main management events of the year 2007 are presented. (A.L.B.)

  1. Life sciences at CEA

    International Nuclear Information System (INIS)

    2000-01-01

    This paper presents briefly the organization of the - Direction des Sciences du Vivant - of french atomic energy commission (Commissariat a l'Energie Atomique (CEA)) and their main axes of research (F.M)

  2. TFR, the tokamak of Fontenay-aux-Roses

    International Nuclear Information System (INIS)

    1985-06-01

    Twelve years of the TFR tokamak operation are briefly reviewed. In the historical introduction, justifications of the experiment and main development stages are described. The importance of the choice of materials in contact with the plasma (impurities production) appears in the various paragraphs. The power lost by impurity radiation is compared with other losses in ohmic conditions (paragraph 2). Additional heating experiments: neutral beam heating paragraph 3 and ion cyclotron heating paragraph 4 are reported; their efficiency as well as deleterious induced effects are described. Important diagnostics development to measure impurities were made, giving experimental results used also in astrophysics and atomic physics. In the last paragraph magnetohydrodynamic phenomena are reported

  3. Robots in the Roses

    OpenAIRE

    2014-01-01

    2014-04 Robots in the Roses A CRUSER Sponsored Event. The 4th Annual Robots in the Roses provides a venue for Faculty & NPS Students to showcase unmanned systems research (current or completed) and recruit NPS Students to join in researching on your project. Posters, robots, vehicles, videos, and even just plain humans welcome! Families are welcome to attend Robots in the Roses as we'll have a STEM activity for children to participate in.

  4. Roses for Autism

    Science.gov (United States)

    Tomaino, Robert

    2011-01-01

    This article discusses Roses for Autism, a program that provides training, guidance and employment opportunities for older students and adults on the autistic spectrum. Roses for Autism tackles one of the biggest challenges currently facing the autism community--a disproportionally high unemployment rate that hovers around 88 percent. Although a…

  5. Encyclopedia of Rose Science

    NARCIS (Netherlands)

    Roberts, A.; Debener, T.; Gudin, S.; Byrne, D.B.; Cairns, T.; Vries, de D.P.; Dubois, L.A.M.; Forkmann, G.; Fruchter, M.; Helsper, J.P.F.G.; Horst, R.K.; Jay, M.; Kwakkenbosch, T.A.M.; Pemberton, B.; Put, H.M.C.; Rajapakse, S.; Reid, M.; Schum, A.; Shorthouse, J.D.; Ueda, Y.; Vainstein, A.; Pol, van de P.A.; Zieslin, N.

    2003-01-01

    The Encyclopedia of Rose Science brings together a wealth of information on the rose, long treasured for its captivating perfumes and splendid colors. Now, more than ever, science plays a central place in the production of this flower at the center of one of the world's biggest floricultural

  6. Characteristics of rose mosaic diseases

    Directory of Open Access Journals (Sweden)

    Marek S. Szyndel

    2013-12-01

    Full Text Available Presented review of rose diseases, associated with the mosaic symptoms, includes common and yellow rose mosaic, rose ring pattern, rose X disease, rose line pattern, yellow vein mosaic and rose mottle mosaic disease. Based on symptomatology and graft transmissibility of causing agent many of those rose disorders are called "virus-like diseases" since the pathogen has never been identified. However, several viruses were detected and identified in roses expressing mosaic symptoms. Currently the most prevalent rose viruses are Prunus necrotic ringspot virus - PNRSV, Apple mosaic virus - ApMV (syn. Rose mosaic virus and Arabis mosaic virus - ArMV Symptoms and damages caused by these viruses are described. Tomato ringspot virus, Tobacco ringspot virus and Rose mottle mosaic virus are also mentioned as rose pa thogcns. Methods of control of rose mosaic diseases are discussed.

  7. CEA 2005 annual report

    International Nuclear Information System (INIS)

    2006-01-01

    This document is the 2005 activity report of the French atomic energy commission (CEA). The CEA is a main actor of nuclear research, development and innovation and is involved in three main domains: energy, defense/security, and information/health technologies thanks to high quality research works. With a manpower of 15000 researchers and collaborators with internationally acknowledged competences, the CEA is a driving force of industrial innovation and develops partnerships with French and European industries. It also warrants the perenniality of nuclear dissuasion. This report presents these different aspects of the CEA activities: 1 - defense-security: simulation program, opening to the scientific community, nuclear warheads, nuclear propulsion, cleansing of Rhone valley facilities, permanent monitoring of treaties respect, fight against terrorism; 2 - energy: optimization of the industrial park, advances in long lived radioactive wastes management, future nuclear systems, cleansing and dismantling integration, European nuclear energy research, new energy technologies; 3 - information and health technologies: major challenge of micro- and nano-technologies, key role of software technologies and complex systems; 4 - big research facilities opened to the scientific and industrial communities; 5 - scientific status: scientific evaluation process, prices and honors; 6 - programs support: revisited strategic control, confirmed simplification, active employment and training policy, teaching and training, technological valorization, international relations, communication, continuous quality approach, mastery of facilities safety, security, environmental control, a key-year for information systems. A financial report is attached to the document. (J.S.)

  8. CEA budget in 1982

    Energy Technology Data Exchange (ETDEWEB)

    1981-12-01

    In 1982, the amount of the CEA budget will be 13.4 billions French Francs. The main characteristics are the priority for employment and investments. In this budget programs are adapted to fit R and D to the government policy: innovation, industrial valorization and fundamental research especially thermonuclear fusion and in the electronuclear field to safety, reprocessing and radioactive waste management.

  9. Presentation of CEA

    International Nuclear Information System (INIS)

    Graf, J.J.

    1976-01-01

    The organization of the CEA, its missions and means are presented. Its activities in the field of light water reactors, fast neutron reactors and PWR reactors of small and medium power for electricity and/or heat generation are emphasized [fr

  10. ROSE MIU Testing

    Science.gov (United States)

    Austin, Rebekah

    2015-01-01

    Overview of work done by Rebekah Austin during Pathways Internship work tour. Describes ROSE MIU (Reconfigurable Operational Spacecraft for Science and Exploration Module Interface Unit) features and test plan.

  11. CEA 2009 annual report

    International Nuclear Information System (INIS)

    2010-01-01

    After an indication of several key figures about the activity of the CEA (Centre d'Etudes Atomiques) and its relationship with the academic as well as the industrial field, in France and worldwide, this 2009 annual report presents its various research programs in the field of defence and of global security: basic research (nuclear weapons and propulsion, struggle against proliferation and terrorism) and applied research (nuclear deterrence, national and international security). Then, it presents the programs in the field of de-carbonated energy: basic research (in material science and in life sciences) and applied research (fission energy, fusion energy, new energy technologies). A last group of research programs deals with information and health technologies and concerns life and material sciences, micro- and nano-technologies, software technologies. Interaction with other research institutions and bodies is also evoked. A brief scientific assessment is proposed. Finally, the different structures building the CEA are presented

  12. CEA - Annual report 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The CEA, a prominent player in research development and innovation, is active in 3 main areas: energy, health care and information technology and defense and security. This annual report presents the CEA activity for the year 2006 in these three main areas: Science and technology working for nuclear deterrence and global security (the simulation programs, the nuclear warheads, the nuclear propulsion, the decommissioning, the fighting against nuclear proliferation and monitoring international treaties, the global security); health and information technology (micro and nano technologies and systems); energy from nuclear fission and fusion and other technologies that do not emit greenhouse gases (progress for the nuclear industry, sustainable management of radioactive materials and waste, nuclear systems of the future, new energy technologies). (A.L.B.)

  13. Nuclear toxicology at CEA

    International Nuclear Information System (INIS)

    Giustranti, C.

    2001-01-01

    CEA (French commission of atomic energy) has launched a new program dedicated to the study of the transfer of heavy metals and some radionuclides from environment to living beings. The substances that will be studied, are those that are involved in research, medical activities, and in nuclear industry. It means iodine, technetium, trans-uranides (uranium and plutonium), fission products (iodine, cesium), carbon, cobalt, boron and beryllium. This program is composed of 2 axis: the first one concerns the bio-geo-chemical cycles that are involved in transfer and the second axis deals with the detoxication processes that appear in animal and man cells. This program will rely on the strong competencies of CEA in chemistry, radiochemistry, biology, physiology and toxicology. (A.C.)

  14. CEA and mining industry

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    The French atomic energy commission (CEA) is involved in the mining industry in several ways: - in the front-end of the nuclear industry through its daughter companies and participations in the exploration and exploitation of uranium ores, but also of gold and alloy metals with a 26% participation in Eramet company, the world leader of manganese and nickel. This activity is the main occupation of Cogema daughter company, via the Areva holding; - in the back-end of the nuclear fuel cycle with the delicate problem of the management of radioactive wastes; - in parallel with the nuclear industry through an important activity in semiconductor materials (FCI and SMTElectronics); - and finally through various research works on several mineral compounds. This article focusses on the fuel cycle aspects of the CEA activities and concludes with the research works carried out today on thermonuclear fusion. (J.S.)

  15. Postharvest aspects of roses

    Directory of Open Access Journals (Sweden)

    Elka Fabiana Aparecida Almeida

    2017-06-01

    Full Text Available This study aimed to evaluate respiratory activity, color changes and fresh weight variation of ‘Carola’ (red, ‘Avalanche’ (white and ‘Avalanche Chá’ (tea roses for seven days after harvest. Respiratory activity, coloration of petals and fresh weight loss were evaluated. Treatments were composed of three rose cultivars and seven days of evaluation, in a 3 x 7 factorial and a completely randomized design with four replicates of two flowers per plot. To determine the respiratory activity, in addition to the four replicates, an “experimental control” was used as a fifth replicate without roses. ‘Avalanche’ and ‘Avalanche Chá’ roses with petals of similar luminosity showed no browning during days after harvest, but are distinct in terms of chromaticity. ‘Carola’ rose has less shiny petals. On harvest day, the respiratory activity is elevated and reduces later until the fourth day, in which there is elevation of this parameter again coinciding with high fresh weight loss. During days after harvest, small changes in the color of petals were observed; however, the main changes were observed in respiratory activity and fresh weight loss.

  16. Carcinoembryonic antigen (CEA)

    International Nuclear Information System (INIS)

    Ephraim, K.H.; Cox, P.H.; Hamer, C.J.A. v.d.; Berends, W.; Delhez, H.

    1977-01-01

    The carcinoembryonic antigen (CEA) is a complex of antigen determinants and also the carrier of these determinants. Chemically it is a glycoprotein. Its occurrence in blood serum or urine is correlated with malignant disease. Several radioimmunoassays (RIA) have been developed, one by Hoffmann-Laroche and one by the Rotterdam Radiotherapeutic Institute. Both methods and the Hoffmann assay kit are tested. Specifications are given for isolation of the antigen, preparation of the antiserum, and the execution of the RIA. Biochemical and clinical aspects are discussed

  17. Two unnamed Turkish roses

    DEFF Research Database (Denmark)

    Tan, Kit; Zielinski, Jerzy

    2010-01-01

    Rosa ‘Professor Turhan Baytop’ and Rosa ‘Asuman’, two different morphotypes of the fragrant double whiteflowered cultivar of Rosa beggeriana, are formally named and described. They stem from old roses once cultivated in gardens of Central and East Anatolia and now gradually disappearing when...

  18. Rosa L.: rose, briar

    Science.gov (United States)

    Susan E. Meyer

    2008-01-01

    The genus Rosa is found primarily in the North Temperate Zone and includes about 200 species, with perhaps 20 that are native to the United States (table 1). Another 12 to 15 rose species have been introduced for horticultural purposes and are naturalized to varying degrees. The nomenclature of the genus is in a state of flux, making it difficult to number the species...

  19. CEA and its radioactive wastes

    International Nuclear Information System (INIS)

    Marano, S.

    1999-01-01

    CEA annually produces about 3500 tons of radioactive wastes in its 43 basic nuclear installations. CEA ranks third behind EDF and Cogema. Low-level wastes (A wastes) are sent to ANDRA (national agency for the management of nuclear wastes)whereas medium-level wastes (B wastes) are stored by CEA itself. CEA has checked off its storing places and has set up an installation Cedra to process and store ancient and new nuclear wastes. 3 other installations are planned to operate within 6 years: Agate (Cadarache) will treat liquid effluents, Stella (Saclay) will process liquid wastes that are beta or gamma emitters, and Atena (Marcoule) will treat and store radioactive sodium coming from Phenix reactor and IPSN laboratories. The use of plasma torch for vitrifying wastes is detailed, the management of all the nuclear wastes produced by CEA laboratories and installations is presented. (A.C.)

  20. Immunological comparison of ovarian and colonic CEA

    International Nuclear Information System (INIS)

    Burtin, P.; Gendron, M.C.; Maunoury, M.T.; Lamerz, R.; Schnabel, G.

    1982-01-01

    Ovarian and colonic CEA were compared immunologically by means of antisera prepared against each of them. CEAs of both origins were found identical by immunodiffusion methods. In radioimmunological experiments, slight differences were observed between some but not all ovarian CEAs and colonic CEAs and also between different preparations of colonic CEA: no organ specificity of ovarian CEA could be demonstrated. Finally, CEA level was measured in 41 sera of patients with ovarian carcinoma by two radioimmunoassays, one using colonic CEA as tracer and standard and anti-colonic CEA serum, the other using ovarian CEA and anti-ovarian CEA serum: the values given by the two assays were highly correlated (rsub(s) = 0.8107), meaning that an organ specific assay for ovarian CEA is not needed. (Auth.)

  1. CEA Annual report 2007; CEA rapport annuel 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The CEA, a prominent player in research development and innovation, is active in three main domains: energy, health care and information technology, defense and security. This annual report presents the CEA activities for the year 2007 in these three main areas: science and technology working for nuclear deterrence and global security, the energies without greenhouse effect gases emission against the climatic change, researches in the information sciences and technologies for a better communication and health. The CEA safety, organization, communication and international relations are also presented. (A.L.B.)

  2. CEA sustainable development report 2007; CEA rapport developpement durable 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The CEA, a prominent player in research development and innovation, is active in three main domains: energy, health care and information technology, defense and security. This annual report presents the CEA activities in the domain of the sustainable development. The first part is devoted to the environment preservation policy (energy, water, air, chemistry, wastes, transport, buildings). The second part shows the dynamic governance in the domain of the risks management. The last part presents the CEA activities of research for the sustainable development. (A.L.B.)

  3. The use and evolution of the CEA research reactors

    International Nuclear Information System (INIS)

    Rossillon, F.; Chauvez, C.

    1964-01-01

    The authors successively examine the different research reactors in use in the French C.E.A. Nuclear Centres. They trace briefly their histories, describing how they have been used up to the present, and how they have been adapted to changes in programme by means of certain modifications. They also describe the reasons which have led to the elaboration of the project for the new reactor Osiris. Zoe, the oldest reactor in the CEA, has been in service in the Centre de Fontenay-aux-Roses since 1948. It is used mainly for measurements of absorption cross-sections in graphite, and for various short irradiations which do not require high fluxes. The reactor EL 2, in service since 1952, was used for the first studies on gas cooling. It has also been widely used for the production of radioisotopes and for a large number of experiments in the fields of physics, metallurgy and physical chemistry. The ageing of certain elements of the reactor has led to the decision to close it down in the near future The reactor EL 3 has been widely used for experiments in physics and in the investigation of fuels. The possibilities of the reactor in fast neutron irradiations will be considerably improved by the adoption of a new type of core (the 'snow crystal' structure). Triton-I, a 2 MW swimming-pool reactor, is used for the most part for fast neutron and gamma irradiations. The modifications being carried out on it at present should result in an increase in the power of the reactor up to 4 or 5 MW. In a neighbouring compartment is housed Triton-II which is of the same general structure, as Triton-I, but whose maximum power is 100 kW. Triton-II is used solely for studies on shielding. Melusine, a 2 MW swimming-pool reactor, has been in use in the Centre d'Etudes Nucleaires de Grenoble since 1959. It has supported a very high programme concerned mainly with solid state physics, fundamental research into refractory fissile materials and special graphites, and the study of the behaviour of

  4. CEA financial report 2007; CEA rapport financier 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This document provides financial data on the CEA for the year 2007. The management report (budget, resources, expenditures) and the accounting are detailed. The main management events of the year 2007 are presented. (A.L.B.)

  5. CEA sustainable development report 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The CEA, a prominent player in research development and innovation, is active in three main domains: energy, health care and information technology, defense and security. This annual report presents the CEA activities in the domain of the sustainable development. The first part is devoted to the environment preservation policy (energy, water, air, chemistry, wastes, transport, buildings). The second part shows the dynamic governance in the domain of the risks management. The last part presents the CEA activities of research for the sustainable development. (A.L.B.)

  6. CEA - Risk control report 2014

    International Nuclear Information System (INIS)

    Verwaerde, Daniel; Bonnevie, Edwige; Maillot, Bernard

    2015-06-01

    After introductory presentations by CEA managers in charge of risk management and controls, this document presents and comments the actions undertaken by the CEA and the obtained results in terms of risk management in different fields: environment protection and control, facilities safety, health and radiation protection, transport of hazardous materials, waste management, sites protection, installations and assets, emergency response, legal risk management, internal inspections and audits. Other topics are addressed like the presentation of the risk control sector, and the role of the CEA in the relationship between research and industry

  7. CEA - 2014 risk management assessment

    International Nuclear Information System (INIS)

    Bonnevie, Edwige; Verwaerde, Daniel; Maillot, Bernard

    2015-06-01

    After introducing presentations of CEA managers in charge of risk management and controls, this document presents and comments the actions undertaken by the CEA and the obtained results in terms of risk management in different fields: protection and control of the environment, installation safety, health, safety and radiation protection, transport of hazardous materials, waste management, protection of sites, installations and heritage, management of emergency situations, management of legal risks, internal audits and controls. Other topics are addressed like the presentation of the risk management department, and the role of the CEA in the relationship between research and industry

  8. In vivo localization of radiolabeled monoclonal antibody to carcinoembryonic antigen (CEA) in a CEA-producing tumor

    International Nuclear Information System (INIS)

    Kamei, Tetsuya; Seto, Hikaru; Taki, Kuniyasu; Soya, Toshio; Kakishita, Masao; Maeda, Masatoshi; Honda, Takashi; Koshimura, Saburou.

    1987-01-01

    To compare accumulation of the 125 I-labeled antibodies(anti-carcinoembryonic antigen(CEA) monoclonal antibody and polyclonal antibody) to a CEA-producing tumor (SC-2-JCK), an in vivo localization study was performed in nude mice. The tumor-to-blood ratio at 120 hours after injection rose to 4.6 for the monoclonal antibody, but remained at 1.3 for the polyclonal antibody. However, no differences were noted between the antibodies up to 72 hours after injection. In autoradiograms, selective accumulation of the tracer was noted in the tumor for both antibodies. However, no superiority or inferiority of imaging for either of the antibodies could be definitely determined. (author)

  9. Space Rose Pleases the Senses

    Science.gov (United States)

    2002-01-01

    International Flavors and Fragrances (IFF), Inc., discovered a new scent by flying a miniature rose plant aboard NASA's Space Shuttle Discovery Flight STS-95. IFF and the Wisconsin Center for Space Automation and Robotics (WCSAR) partnered to fly the rose plant in the commercial plant research facility, ASTROCULTURE(TM), for reduced-gravity environment research. IFF commercialized the space rose note, which is now a fragrance ingredient in a perfume developed by Shiseido Cosmetics (America), Ltd. In addition to providing a light crisp scent, the oil from the space rose can also serve as a flavor enhancer. ASTROCULTURE(TM) is a trademark of the Wisconsin Center for Space Automation and Robotics.

  10. Scientific evaluation at the CEA; Evaluation scientifique au CEA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    This report presents a statement of the scientific and technical activity of the French atomic energy commission (CEA) for the year 1998. This evaluation is made by external and independent experts and requires some specific dispositions for the nuclear protection and safety institute (IPSN) and for the direction of military applications (DAM). The report is divided into 5 parts dealing successively with: part 1 - the CEA, a public research organization (civil nuclear research, technology research and transfers, defence activities); the scientific and technical evaluation at the CEA (general framework, evaluation of the IPSN and DAM); part 2 - the scientific and technical councils (directions of fuel cycle, of nuclear reactors, and of advanced technologies); part 3 - the scientific councils (directions of matter and of life sciences); the nuclear protection and safety institute; the direction of military applications; part 4 - the corresponding members of the evaluation; part 5 - the list of scientific and technical councils and members. (J.S.)

  11. Axillary bud development in rose

    NARCIS (Netherlands)

    Marcelis - van Acker, C.A.M.

    1994-01-01

    Axillary buds form the basis of flower production of a rose crop. Within a rose crop there exists an undesired large variation in shoot number and size, which affects flower yield. Part of this variation may be traced back to early variation in axillary buds. The aim of the research

  12. Scientific evaluation at the CEA

    International Nuclear Information System (INIS)

    1999-01-01

    This report presents a statement of the scientific and technical activity of the French atomic energy commission (CEA) for the year 1998. This evaluation is made by external and independent experts and requires some specific dispositions for the nuclear protection and safety institute (IPSN) and for the direction of military applications (DAM). The report is divided into 5 parts dealing successively with: part 1 - the CEA, a public research organization (civil nuclear research, technology research and transfers, defence activities); the scientific and technical evaluation at the CEA (general framework, evaluation of the IPSN and DAM); part 2 - the scientific and technical councils (directions of fuel cycle, of nuclear reactors, and of advanced technologies); part 3 - the scientific councils (directions of matter and of life sciences); the nuclear protection and safety institute; the direction of military applications; part 4 - the corresponding members of the evaluation; part 5 - the list of scientific and technical councils and members. (J.S.)

  13. The CEA's waste management strategy

    International Nuclear Information System (INIS)

    Behar, Ch.; Dall'ava, D.; Fillion, E.

    2011-01-01

    The CEA is tasked with carrying out certain research activities: within the Military Applications Division (DAM), research is focused on the nuclear deterrence and, within the Nuclear Energy Division, on developing the industrial nuclear systems of the future and optimising existing nuclear systems in partnership with EDF and AREVA. These major research and development themes entail a need for nuclear research and support facilities which must be maintained at a high level of performance and safety and, also, constantly upgraded to handle the research activities and programmes for which they are used. The CEA strategy is based on the right packaging of the radioactive liquid or solid waste into a form required for its transport, storage or disposal. The Caraibes software allows an efficient traceability of the waste packages. Most of the radioactive effluent processing stations of CEA are being upgraded

  14. CEA Annual progress report 1986

    International Nuclear Information System (INIS)

    1987-01-01

    This annual report presents the general organization of the CEA, the international relations and politics in nuclear field, the activities (military application, nuclear applied research, ANDRA (National Agency for Radioactive Waste Management), nuclear safety and protection, fundamental research, applied research other than nuclear), the industrial group; among topics about men and means, the budget execution of the public establishment of research. In annex, the nuclear power plants around the world and the principal legislative texts related to CEA or atomic energy published in 1986 [fr

  15. CEA 2005 annual report; CEA rapport annuel 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document is the 2005 activity report of the French atomic energy commission (CEA). The CEA is a main actor of nuclear research, development and innovation and is involved in three main domains: energy, defense/security, and information/health technologies thanks to high quality research works. With a manpower of 15000 researchers and collaborators with internationally acknowledged competences, the CEA is a driving force of industrial innovation and develops partnerships with French and European industries. It also warrants the perenniality of nuclear dissuasion. This report presents these different aspects of the CEA activities: 1 - defense-security: simulation program, opening to the scientific community, nuclear warheads, nuclear propulsion, cleansing of Rhone valley facilities, permanent monitoring of treaties respect, fight against terrorism; 2 - energy: optimization of the industrial park, advances in long lived radioactive wastes management, future nuclear systems, cleansing and dismantling integration, European nuclear energy research, new energy technologies; 3 - information and health technologies: major challenge of micro- and nano-technologies, key role of software technologies and complex systems; 4 - big research facilities opened to the scientific and industrial communities; 5 - scientific status: scientific evaluation process, prices and honors; 6 - programs support: revisited strategic control, confirmed simplification, active employment and training policy, teaching and training, technological valorization, international relations, communication, continuous quality approach, mastery of facilities safety, security, environmental control, a key-year for information systems. A financial report is attached to the document. (J.S.)

  16. The CEA budget in 1982

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    In 1982, the amount of the CEA budget will be 13.4 billions French Francs. The main characteristics are the priority for employment and investments. In this budget programs are adapted to fit R and D to the government policy: innovation, industrial valorization and fundamental research especially thermonuclear fusion and in the electronuclear field to safety, reprocessing and radioactive waste management [fr

  17. Nondestructive testing at the CEA

    International Nuclear Information System (INIS)

    Colomer, J.; Lucas, G.

    1976-01-01

    The different nondestructive testing methods used at the CEA are presented: X-ray or gamma radiography, X-ray stress analysis, neutron radiography, ultrasonic testing, eddy currents, electrical testing, microwaves, thermal testing, acoustic emission, optical holography, tracer techniques. (102 references are cited) [fr

  18. Aux origines du monde

    CERN Multimedia

    2004-01-01

    "C'est l'histoire d'une aventure humaine, scientifique, international qui a vu le jour il y a cinquante ans, aux confins de la Suisse et du département de l'Ain. Le plus grand laboratoire de physique des particules du monde, le Cern, a été fondé en 1954. Les festivités organisées à l occasion de cet anniversaire connaîtront leur point d'orgue le 16 octobre prochain, avec portes-ouvertes, accueil de personallités et inauguration d'un monumnet spécifique, le Globe de l'innovation" (2 pages)

  19. CEA - Annual report 2006; CEA - Rapport annuel 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The CEA, a prominent player in research development and innovation, is active in 3 main areas: energy, health care and information technology and defense and security. This annual report presents the CEA activity for the year 2006 in these three main areas: Science and technology working for nuclear deterrence and global security (the simulation programs, the nuclear warheads, the nuclear propulsion, the decommissioning, the fighting against nuclear proliferation and monitoring international treaties, the global security); health and information technology (micro and nano technologies and systems); energy from nuclear fission and fusion and other technologies that do not emit greenhouse gases (progress for the nuclear industry, sustainable management of radioactive materials and waste, nuclear systems of the future, new energy technologies). (A.L.B.)

  20. INIS, CEA and nuclear terminology; INIS, CEA et terminologie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Surmont, J.; Brulet, C.; Constant, A.; Guille, N.; Le Blanc, A.; Mouffron, O.; Anguise, P.; Jouve, J.J

    2007-07-01

    This poster, prepared for the fifth edition of the meetings of scientific and technical information professionals (RPIST, Nancy (France)), presents, first, the INIS information system, its content and coverage, the French participation to this system and the role of the CEA-Saclay as France's official representative for this system. Then it presents the INIS thesaurus with its different levels as a terminological tool for the indexing of documents and for searching documents inside the database. Finally, the very first electronic version of the multilingual thesaurus is introduced. Several national INIS centres, including the CEA-Saclay, have contributed to the translation of lists of new terms and of forbidden terms (synonyms). (J.S.)

  1. CEA 2009 annual report; CEA rapport annuel 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    After an indication of several key figures about the activity of the CEA (Centre d'Etudes Atomiques) and its relationship with the academic as well as the industrial field, in France and worldwide, this 2009 annual report presents its various research programs in the field of defence and of global security: basic research (nuclear weapons and propulsion, struggle against proliferation and terrorism) and applied research (nuclear deterrence, national and international security). Then, it presents the programs in the field of de-carbonated energy: basic research (in material science and in life sciences) and applied research (fission energy, fusion energy, new energy technologies). A last group of research programs deals with information and health technologies and concerns life and material sciences, micro- and nano-technologies, software technologies. Interaction with other research institutions and bodies is also evoked. A brief scientific assessment is proposed. Finally, the different structures building the CEA are presented

  2. INIS, CEA and nuclear terminology

    International Nuclear Information System (INIS)

    Surmont, J.; Brulet, C.; Constant, A.; Guille, N.; Le Blanc, A.; Mouffron, O.; Anguise, P.; Jouve, J.J.

    2007-01-01

    This poster, prepared for the fifth edition of the meetings of scientific and technical information professionals (RPIST, Nancy (France)), presents, first, the INIS information system, its content and coverage, the French participation to this system and the role of the CEA-Saclay as France's official representative for this system. Then it presents the INIS thesaurus with its different levels as a terminological tool for the indexing of documents and for searching documents inside the database. Finally, the very first electronic version of the multilingual thesaurus is introduced. Several national INIS centres, including the CEA-Saclay, have contributed to the translation of lists of new terms and of forbidden terms (synonyms). (J.S.)

  3. CEA: risk management assessment 2011

    International Nuclear Information System (INIS)

    Bigot, Bernard; Bonnevie, Edwige; Maillot, Bernard

    2012-01-01

    This report proposes a qualitative and quantitative overview of CEA activities in the field of risk management during 2011. These activities concerned the impact on the environment, the safety of installations, the management of professional risks (safety and health at work), the radiological protection of workers, the transports of hazardous materials, waste management, protection of sites, installations and heritage, the management of emergency situations, the management of law risks, controls and audits

  4. The use and evolution of the CEA research reactors; Utilisation et evolution des reacteurs de recherche du C.E.A

    Energy Technology Data Exchange (ETDEWEB)

    Rossillon, F; Chauvez, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    The authors successively examine the different research reactors in use in the French C.E.A. Nuclear Centres. They trace briefly their histories, describing how they have been used up to the present, and how they have been adapted to changes in programme by means of certain modifications. They also describe the reasons which have led to the elaboration of the project for the new reactor Osiris. Zoe, the oldest reactor in the CEA, has been in service in the Centre de Fontenay-aux-Roses since 1948. It is used mainly for measurements of absorption cross-sections in graphite, and for various short irradiations which do not require high fluxes. The reactor EL 2, in service since 1952, was used for the first studies on gas cooling. It has also been widely used for the production of radioisotopes and for a large number of experiments in the fields of physics, metallurgy and physical chemistry. The ageing of certain elements of the reactor has led to the decision to close it down in the near future The reactor EL 3 has been widely used for experiments in physics and in the investigation of fuels. The possibilities of the reactor in fast neutron irradiations will be considerably improved by the adoption of a new type of core (the 'snow crystal' structure). Triton-I, a 2 MW swimming-pool reactor, is used for the most part for fast neutron and gamma irradiations. The modifications being carried out on it at present should result in an increase in the power of the reactor up to 4 or 5 MW. In a neighbouring compartment is housed Triton-II which is of the same general structure, as Triton-I, but whose maximum power is 100 kW. Triton-II is used solely for studies on shielding. Melusine, a 2 MW swimming-pool reactor, has been in use in the Centre d'Etudes Nucleaires de Grenoble since 1959. It has supported a very high programme concerned mainly with solid state physics, fundamental research into refractory fissile materials and special graphites, and the study of the behaviour of

  5. In vitro mutagenesis of roses

    International Nuclear Information System (INIS)

    Salahbiah Abdul Majid; Rusli Ibrahim

    2006-01-01

    In roses, numerous in vivo mutation induction experiments have been described, but only a few commercial mutants were published. The reason for this restriction may be that it sometimes takes a few years before mutants can be isolated and propagated by conventional methods. Roses mutate readily and most selected mutants concern flower colour, shape and plant type. A major problem for improvement of roses by means of mutation breeding is chimera formation, particularly when it aims to induce changes in quantitative characters. In vitro propagation could probably accelerate the isolation of periclinal chimera. Studies were conducted to investigate the potential of using gamma rays in orderto get mutations. Dormant axillary bud explants subjected to increasing doses of gamma rays showed a decrease in regeneration capacity, which was completely suppressed at 100 Gy. The lethal dose for 50 % of the regenerating explants (LD50) for both cut and miniature roses were observed between 20-40 Gy. For the main experiment, doses between 20 and 40 Gy were found to be most suitable for the induction of high mutation rate. A few new flower mutants, with new colour and shape were selected for further testing in order to produce stable mutants and this had to be micro propagated for a few generations. Thus, using axillary bud explants for the induction of mutation through in vitro shoots regeneration, several potential stable mutants of horticultural value were isolated. (Author)

  6. Rose breeding: past, present, prospects

    NARCIS (Netherlands)

    Vries, de D.P.; Dubois, L.A.M.

    1996-01-01

    In this review the PAST, PRESENT and PROSPECT will be considered as three separate periods in the history of the breeding and development of rose cultivars. The recurring theme is the genetic variation. This theme was chosen because there is justified doubt as to sufficient genetic variation

  7. Numerical prediction of rose growth

    NARCIS (Netherlands)

    Bernsen, E.; Bokhove, Onno; van der Sar, D.M.

    2006-01-01

    A new mathematical model is presented for the prediction of rose growth in a greenhouse. Given the measured ambient environmental conditions, the model consists of a local photosynthesis model, predicting the photosynthesis per unit leaf area, coupled to a global greenhouse model, which predicts the

  8. The Rose Art Museum Crisis

    Science.gov (United States)

    Dillon, Paul

    2010-01-01

    On January 26, 2009, the Brandeis University Board of Trustees voted unanimously to close the Rose Art Museum (Waltham, Massachusetts). The proceeds from the subsequent auction were to be reinvested in the university to ensure its long-term financial health. The reaction to the decision by campus constituencies provides a case study to show the…

  9. Micropropagation of rose cultivar 'Pareo'

    African Journals Online (AJOL)

    Jane

    2011-08-22

    Aug 22, 2011 ... Serik Mukhambetzhanov*, Svetlana Nam, Valentina Mursalieva and Izbasar Rakhimbaev. Laboratory of Clonal Propagation, Institute of Plant Biology and Biotechnology, 050040 Almaty, Kazakhstan. Accepted 1 July, 2011. A protocol was developed for micropropagation of rose cv. 'Pareo'. Nodal segments ...

  10. CEA - Assessment of risk management 2013

    International Nuclear Information System (INIS)

    Bigot, Bernard; Bonnevie, Edwige; Maillot, Bernard

    2014-06-01

    After some introducing texts by CEA managers, this report proposes a rather detailed overview and presentation of CEA activities, objectives and obtained results in different fields: protection and control of the environment, installation safety, health, safety and radiation protection, transports of hazardous materials, waste management, protection of sites, installations and heritage, management of emergency situations, management of legal risks, internal controls and audits, activity of the risk management department, CEA activities from research to industry

  11. Decontamination and dismantling at the CEA

    International Nuclear Information System (INIS)

    2006-01-01

    This document presents the dismantling policy at the CEA (French Research Center on the atomic energy), the financing of the decontamination and the dismantling, the regulatory framework, the knowledge and the technology developed at the CEA, the radiation protection, the environment monitoring and the installations. (A.L.B.)

  12. How the CEA sorts out its certifications

    International Nuclear Information System (INIS)

    Lembezat, C.

    2011-01-01

    In order to better manage its numerous certifications, the French CEA decided to implement an integrated management system. It aims at simplifying these certifications, at sharing best practices, and at obtaining a better efficiency. For this project, i.e. the management of quality, safety and environment, the CEA asked for the support of experts in integrated complex system management

  13. Memoirs of a Cea veteran

    Energy Technology Data Exchange (ETDEWEB)

    Puill, A

    2001-07-01

    A brief account is given of the way in which nuclear energy has developed in France and elsewhere over the last fifty years: options developed by the French Atomic Energy Commission (CEA), naval propulsion, development of pressurised water reactors, MOX and thorium fuels. Afterwards, the prospectives for the 21. century will be discussed. Considering that natural resources are depleting while releases of both greenhouse gases and world population are increasing, an active energy policy will have to be implemented with due consideration for social equity and solidarity. It is in this context that the developed countries will have to give preference, beyond savings, to renewable sources of energy, including of course, nuclear energy. Nuclear energy can continue to develop in the long term, provided fast breeder technology is developed at some point. As far as transport is concerned, hydrogen technology, which is clean and renewable, is promising, provided it is generated by nuclear energy. (author)

  14. CEA SMAD 2016 Digitizer Evaluation.

    Energy Technology Data Exchange (ETDEWEB)

    Merchant, Bion J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-08-01

    Sandia National Laboratories has tested and evaluated an updated SMAD digitizer, developed by the French Alternative Energies and Atomic Energy Commission (CEA). The SMAD digitizers are intended to record sensor output for seismic and infrasound monitoring applications. The purpose of this digitizer evaluation is to measure the performance characteristics in such areas as power consumption, input impedance, sensitivity, full scale, self-noise, dynamic range, system noise, response, passband, and timing. The SMAD digitizers have been updated since their last evaluation by Sandia to improve their performance when recording at a sample rate of 20 Hz for infrasound applications and 100 Hz for hydro-acoustic seismic stations. This evaluation focuses primarily on the 20 Hz and 100 Hz sample rates. The SMAD digitizers are being evaluated for potential use in the International Monitoring System (IMS) of the Comprehensive Nuclear Test- Ban-Treaty Organization (CTBTO).

  15. Memoirs of a Cea veteran

    International Nuclear Information System (INIS)

    Puill, A.

    2001-01-01

    A brief account is given of the way in which nuclear energy has developed in France and elsewhere over the last fifty years: options developed by the French Atomic Energy Commission (CEA), naval propulsion, development of pressurised water reactors, MOX and thorium fuels. Afterwards, the prospectives for the 21. century will be discussed. Considering that natural resources are depleting while releases of both greenhouse gases and world population are increasing, an active energy policy will have to be implemented with due consideration for social equity and solidarity. It is in this context that the developed countries will have to give preference, beyond savings, to renewable sources of energy, including of course, nuclear energy. Nuclear energy can continue to develop in the long term, provided fast breeder technology is developed at some point. As far as transport is concerned, hydrogen technology, which is clean and renewable, is promising, provided it is generated by nuclear energy. (author)

  16. "Entitlement Means Prescription": Exploring the Rose Review

    Science.gov (United States)

    Silcock, Peter

    2010-01-01

    The Rose Review makes a number of worthy recommendations deserving implementation, especially those advising a gradual, three-phase shift towards subject-based studies from play-based practices. But Rose's attempt to make the Primary Curriculum manageable does not and probably could not succeed. The content-led nature of a Rose-Reviewed…

  17. CEA - 2012 Annual Report, 2012 Financial Statements

    International Nuclear Information System (INIS)

    2013-01-01

    In its first part, this report proposes an overview of activities within the CEA. They concern the CEA's programs on low on carbon energies and associated fundamental researches, on defence and global security and associated fundamental researches, on information technologies and associated fundamental researches, on health technologies and associated fundamental researches, and on very large research infrastructures and associated fundamental researches. The second part addresses the scientific assessment, activities related to teaching and training, to innovation towards enterprises, and to support to valorization. It also indicates prices awarded to the CEA. The third part addresses CEA management and institutional relationships, human resources, international relationships, activities related to communication and information diffusion, and risk management. The fourth part describes the CEA organization, its governance and its various bodies. The second volume contains the financial statements for 2012

  18. Elaboration of an alpha-numeric classification for file of matters of the documentation service of the CEA; Elaboration d'une classification alfha-numerique pour le fichier matieres du service de documentation du Commissariat a l'Energie Atomique

    Energy Technology Data Exchange (ETDEWEB)

    Braffort, P [Commissariat a l' Energie Atomique, Saclay(France). Centre d' Etudes Nucleaires

    1953-07-01

    We give the principles of a classification of matters to square basis, suiting the needs of the Service, of Documentation of the C.E.A. We present the detail of the categories in the order of the 'columns', likewise the big scientific subdivisions at the CEA. (authors) [French] On donne les principes d'une classification matieres a base carree, convenant aux besoins du Service de Documentation du C.E.A. On presente ensuite le detail des rubriques dans l'ordre des ''colonnes'', c'est-a-dire, des grandes subdivisions scientifiques du C.E.A. (auteurs)

  19. CEA - 2011 annual report, 2011 financial statement

    International Nuclear Information System (INIS)

    2012-06-01

    The first report, available both in French and English, presents the different current programs: low carbon energies and associated fundamental researches, global defence and safety and associated researches, information technologies and associated researches, technologies for health and associated fundamental researches, very large research infrastructures and associated fundamental researches. It then addresses the CEA openness: assessment, teaching and training, research valorisation, awards, and the support to various programs: steering activity by the CEA, human resources, international relationships, communication, risk management, information systems. The last part describes the CEA organisation. The second report presents the different financial and accounting data and tables

  20. Operational safety at the radiometallurgy laboratory of Fontenay-aux-Roses

    International Nuclear Information System (INIS)

    Hayet, Lucien; Petit, Pierre; Conche, Roger.

    1976-01-01

    Opened in 1967, the Radiometallurgy Laboratory is responsible for the examination of plutonium 239 based nuclear fuels of breeder reactors such as Rapsodie and Phenix. Part of the same laboratory is also responsible for the manufacture of californium 252 sources. These neutron sources can have a neutron fluency yield of 2,3 10 10 n/s/4π (i.e. 10mg of 252cf). This large laboratory includes a total area of 117m 2 of hot surfaces. It also includes 14 high activity cells with a capacity of 100000Ci at 1MeV. Located only 7km from the center of Paris, it must incorporate a special design and a particularly sure safety policy. Several statistics are given: irradiations, contaminations, incidents, quantity of fissile material, solid and liquid wastes etc... The principles of safety management are outlined and an analysis given of this basic nuclear facility [fr

  1. The CEA-Industrie Group of Companies

    International Nuclear Information System (INIS)

    1988-01-01

    The 1988 financial and technological status of the CEA-Industry Group of Companies is summarized. The activities, technological innovations, and areas of development perspectives of the CEA-Industry Group of Companies, chiefly concentrated in fields relating to nuclear energy, are described. The principal business sectors of the group involve nuclear fuel cycle, nuclear plants and maintenance, computer applications and life science. Some activities of the group are extended to management, construction and financial fields

  2. Saclay - 50 years / CEA 1945-95

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    Central in the infrastructure through which France obtains some 80% of its electric power from nuclear energy stands the French Atomic Energy Authority (Commissariat à l'Energie Atomique - CEA). This year the CEA celebrates its Golden Jubilee. Mastery of nuclear energy goes hand-in-hand with fundamental research in the fields of nuclear and sub-nuclear physics, and the founders of the CEA, like F. Joliot and F. Perrin, considered it essential to relaunch fundamental research in France after the Second World War. In particular, A. Messiah's courses on quantum mechanics made a considerable contribution to the re-establishment of a French school of atomic and sub-atomic physics. As the CEA expanded and nuclear industry grew up, the need was shown for close links between fundamental research and its applications. In addition, the CEA realized how important it was to become a part of the national and international scientific community as highly effective cooperation was developing. The CEA has drawn a wealth of scientific, cultural and intellectual benefits from its collaboration with CERN. During the same period, as fundamental particle physics research has been making spectacular progress, its requirements have grown commensurately. It is not therefore surprising that CERN needs partners capable of bringing together the domains of fundamental research and major equipment and of promoting a dialogue between research and industry. As was pointed out by Jacques Haissinski, head of the Department of Astrophysics, Particle Physics, Nuclear Physics and Associated Instruments (DAPNIA), the CEA, set up to develop major programmes for applying nuclear processes, is particularly well equipped to design, build and operate the huge instruments for exploring the infinitely small and the infinitely large. Tomorrow's nuclear industry needs and will continue to need fundamental research, with its openness and its cooperation. Particle physics needs and will continue

  3. CEA - Assessment of risk management for 2012

    International Nuclear Information System (INIS)

    Bonnevie, Edwige

    2013-06-01

    This report proposes an overview of the main events, actions performed by the CEA, and facts for 2012 regarding protection and monitoring of the environment, installation safety, occupational health and safety, radiological protection of workers, transportation of hazardous materials, waste management, protection of sites, installations and heritage, emergency situation management, legal risk management, internal controls and audits. It also presents the organisation and action of the risk management department within the CEA

  4. The CEA in mutation redefines its strategy

    International Nuclear Information System (INIS)

    Anon.

    2005-01-01

    The French atomic energy commission has redefined its medium- and long-term plan which fixes its strategy for the ten coming years. A. Bugat, general director of the CEA briefly presents the new missions of the CEA: budget and investments, cooperation with universities, place of fundamental research, activities in fuel cells and photovoltaic energy, cooperation with EdF, Areva and Cogema in civil nuclear research. Short paper. (J.S.)

  5. 1999 scientific evaluation at the CEA

    International Nuclear Information System (INIS)

    1999-01-01

    This report presents a statement of the scientific and technical activity of the French atomic energy commission (CEA) for the year 1999. This evaluation is made by external and independent experts and requires some specific dispositions for the nuclear protection and safety institute (IPSN) and for the direction of military applications (DAM). The report is divided into 4 parts dealing successively with: 1)the CEA, a public research organization (strategy, research programs, new organization of the CEA activities, civil nuclear research, technology research and transfer, defence activities, transfer of knowledge) 2)the scientific evaluation at the CEA (evaluations of the civil applications of the CEA, IPSN, DAM, INSTN (national institute for nuclear sciences and techniques) 3)synthesis of the 1999 scientific and technical evaluation for each operational directions of the CEA (directions of fuel cycle, of nuclear reactors, of advanced technologies, of materials sciences, of life sciences, of military applications, of the nuclear protection and safety institute and of the national institute for nuclear sciences and techniques) 4)the corresponding members of the evaluation and the list of scientific and technical councils and members

  6. Decontamination and dismantling at the CEA; L'assainissement et le demantelement au CEA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document presents the dismantling policy at the CEA (French Research Center on the atomic energy), the financing of the decontamination and the dismantling, the regulatory framework, the knowledge and the technology developed at the CEA, the radiation protection, the environment monitoring and the installations. (A.L.B.)

  7. A molecular marker map for roses

    NARCIS (Netherlands)

    Debener, T.; Mattiesch, L.; Vosman, B.

    2001-01-01

    n addition to an existing core map for diploid roses which comprised 305 molecular markers 60 additional markers were mapped to extend the map. As a first application of the information contained in the map, the map position of a resistance gene from roses, Rdr1, was determined by identifying

  8. Rose's Life Lessons: Signed and Spoken

    Science.gov (United States)

    McAuliffe, Chris

    2008-01-01

    In this article, the author shares the experiences of his wife, Cheryl, and his 5-year-old daughter, Rose, when they visited their local high school's child development class. Cheryl and Rose met with over a 100 teenagers teenagers in eight different classes to talk about their family, raising a child with Down syndrome, and their experiences with…

  9. Improving rooting uniformity in rose cuttings

    NARCIS (Netherlands)

    Telgen, van H.J.; Eveleens-Clark, B.A.; Garcia Victoria, N.

    2007-01-01

    Studies to improve rooting uniformity of single node stem cuttings for rose are reported. We found that the variation in shoot growth in a young rose crop depended on the variation in root number of the cuttings, which, in turn, was related to the auxin concentration applied to the cutting before

  10. Scheduling techniques in the Request Oriented Scheduling Engine (ROSE)

    Science.gov (United States)

    Zoch, David R.

    1991-01-01

    Scheduling techniques in the ROSE are presented in the form of the viewgraphs. The following subject areas are covered: agenda; ROSE summary and history; NCC-ROSE task goals; accomplishments; ROSE timeline manager; scheduling concerns; current and ROSE approaches; initial scheduling; BFSSE overview and example; and summary.

  11. Reagents for radioimmunological determination of carcinoembryonic antigen (CEA)

    International Nuclear Information System (INIS)

    Albert, Z.; Balbierz, H.; Breberowicz, J.

    1978-01-01

    The work was undertaken to prepare the reagents for carcinoembryonic antigen (CEA) radioimmunoassay with double antibody method. The CEA standard of high immunoreactivity was prepared and purified. The purified CEA was used for immunozation of goats. The goat anti - CEA sera were received. IgG fraction from normal goat serum was purified and used for the production of horse anti-goat IgG serum which was then used in the radioimmunoassay of CEA. The labelling of CEA with iodine-125 has been carried out be means of the enzymatic method.(Z.R.)

  12. Dispersion of Radionuclides and Exposure Assessment in Urban Environments: A Joint CEA and LLNL Report

    Energy Technology Data Exchange (ETDEWEB)

    Glascoe, Lee [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gowardhan, Akshay [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lennox, Kristin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Simpson, Matthew [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Yu, Kristen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Armand, Patrick [Alternative Energies and Atomic Energy Commission (CEA), Paris (France); Duchenne, Christophe [Alternative Energies and Atomic Energy Commission (CEA), Paris (France); Mariotte, Frederic [Alternative Energies and Atomic Energy Commission (CEA), Paris (France); Pectorin, Xavier [Alternative Energies and Atomic Energy Commission (CEA), Paris (France)

    2014-12-19

    In the interest of promoting the international exchange of technical expertise, the US Department of Energy’s Office of Emergency Operations (NA-40) and the French Commissariat à l'Energie Atomique et aux énergies alternatives (CEA) requested that the National Atmospheric Release Advisory Center (NARAC) of Lawrence Livermore National Laboratory (LLNL) in Livermore, California host a joint table top exercise with experts in emergency management and atmospheric transport modeling. In this table top exercise, LLNL and CEA compared each other’s flow and dispersion models. The goal of the comparison is to facilitate the exchange of knowledge, capabilities, and practices, and to demonstrate the utility of modeling dispersal at different levels of computational fidelity. Two modeling approaches were examined, a regional scale modeling approach, appropriate for simple terrain and/or very large releases, and an urban scale modeling approach, appropriate for small releases in a city environment. This report is a summary of LLNL and CEA modeling efforts from this exercise. Two different types of LLNL and CEA models were employed in the analysis: urban-scale models (Aeolus CFD at LLNL/NARAC and Parallel- Micro-SWIFT-SPRAY, PMSS, at CEA) for analysis of a 5,000 Ci radiological release and Lagrangian Particle Dispersion Models (LODI at LLNL/NARAC and PSPRAY at CEA) for analysis of a much larger (500,000 Ci) regional radiological release. Two densely-populated urban locations were chosen: Chicago with its high-rise skyline and gridded street network and Paris with its more consistent, lower building height and complex unaligned street network. Each location was considered under early summer daytime and nighttime conditions. Different levels of fidelity were chosen for each scale: (1) lower fidelity mass-consistent diagnostic, intermediate fidelity Navier-Stokes RANS models, and higher fidelity Navier-Stokes LES for urban-scale analysis, and (2) lower-fidelity single

  13. Dispersion of Radionuclides and Exposure Assessment in Urban Environments: A Joint CEA and LLNL Report

    International Nuclear Information System (INIS)

    Glascoe, Lee; Gowardhan, Akshay; Lennox, Kristin; Simpson, Matthew; Yu, Kristen; Armand, Patrick; Duchenne, Christophe; Mariotte, Frederic; Pectorin, Xavier

    2014-01-01

    In the interest of promoting the international exchange of technical expertise, the US Department of Energy’s Office of Emergency Operations (NA-40) and the French Commissariat à l'Energie Atomique et aux énergies alternatives (CEA) requested that the National Atmospheric Release Advisory Center (NARAC) of Lawrence Livermore National Laboratory (LLNL) in Livermore, California host a joint table top exercise with experts in emergency management and atmospheric transport modeling. In this table top exercise, LLNL and CEA compared each other's flow and dispersion models. The goal of the comparison is to facilitate the exchange of knowledge, capabilities, and practices, and to demonstrate the utility of modeling dispersal at different levels of computational fidelity. Two modeling approaches were examined, a regional scale modeling approach, appropriate for simple terrain and/or very large releases, and an urban scale modeling approach, appropriate for small releases in a city environment. This report is a summary of LLNL and CEA modeling efforts from this exercise. Two different types of LLNL and CEA models were employed in the analysis: urban-scale models (Aeolus CFD at LLNL/NARAC and Parallel- Micro-SWIFT-SPRAY, PMSS, at CEA) for analysis of a 5,000 Ci radiological release and Lagrangian Particle Dispersion Models (LODI at LLNL/NARAC and PSPRAY at CEA) for analysis of a much larger (500,000 Ci) regional radiological release. Two densely-populated urban locations were chosen: Chicago with its high-rise skyline and gridded street network and Paris with its more consistent, lower building height and complex unaligned street network. Each location was considered under early summer daytime and nighttime conditions. Different levels of fidelity were chosen for each scale: (1) lower fidelity mass-consistent diagnostic, intermediate fidelity Navier-Stokes RANS models, and higher fidelity Navier-Stokes LES for urban-scale analysis, and (2) lower-fidelity single

  14. Den danske ROSE-undersøgelse

    DEFF Research Database (Denmark)

    Andersen, Annemarie Møller; Allerup, Peter; Arnvig, Birgitte

    ROSE (Relevance of Science Education) er en international komparativ undersøgelse af 15-åriges holdninger til og interesse for naturfagsundervisning, naturvidenskab og teknologi med deltagelse af ca. 40. lande. Dataindsamlingen til den danske del af ROSE-undersøgelsen blev gennemført i 2003....... Antologien giver et overblik over  og forskellige perspektiver på de danske 15-åriges besvarelser af de ca. 280 spørgsmål i det danske ROSE-skema....

  15. Mutation studies on garden roses: a review

    International Nuclear Information System (INIS)

    Datta, S.K.

    1997-01-01

    Most of the modern roses are the result of hybridization, selection and spontaneous mutation. For floriculture trade, there is always demand and necessity for new varieties due to change in taste and fashion. Mutation breeding is an established method for crop improvement. Induced somatic mutation breeding holds promise for effective improvement and have high potential for bringing about genetic improvement and it has led to a great burst of flower colour, form, pattern and other variations in rose by using ionizing radiations. The details of prospects and utilization of induced mutation breeding technique for developing new rose varieties have been compiled. (author)

  16. [Significance of CEA in gastric and colorectal cancer].

    Science.gov (United States)

    Uehara, K; Miyamoto, Y; Izuo, M; Shiozaki, H; Aiba, S; Matsumoto, H

    1985-04-01

    The determination of serum CEA (Sandwich method) and CEA staining (PAP method) of excised specimens were performed in patients with gastric or colorectal cancer, and the biological characteristics of each cancer and the factors to increase serum CEA were studied with the following results: As colonic cancer has strong CEA productivity, serum CEA can be useful for the detection of cancer, and especially effective for the postoperative observation. Gastric cancer has weak CEA productivity, and serum CEA is not so useful in the detection of cancer and the judgement of resectability. The CEA positive rate of tissue with CEA staining was 80% in gastric cancer, 100% in colonic cancer, and were nearly equal to the CEA positive rate of serum in the group of terminal stage. In the mode of CEA staining of cancerous cells, IV type was observed most frequently in gastric cancer, and I type in colonic cancer. Among the resected cases showing more than 7ng/ml serum CEA, differentiated type, lymph node metastasis (+), the degree of tissue staining with CEA staining, the mode of cell staining O or I type in gastric cancer and I type in colonic cancer were observed in common.

  17. Behavior of Multiclass Pesticide Residue Concentrations during the Transformation from Rose Petals to Rose Absolute.

    Science.gov (United States)

    Tascone, Oriane; Fillâtre, Yoann; Roy, Céline; Meierhenrich, Uwe J

    2015-05-27

    This study investigates the concentrations of 54 multiclass pesticides during the transformation processes from rose petal to concrete and absolute using roses spiked with pesticides as a model. The concentrations of the pesticides were followed during the process of transforming the spiked rose flowers from an organic field into concrete and then into absolute. The rose flowers, the concrete, and the absolute, as well as their transformation intermediates, were analyzed for pesticide content using gas chromatography/tandem mass spectrometry. We observed that all the pesticides were extracted and concentrated in the absolute, with the exception of three molecules: fenthion, fenamiphos, and phorate. Typical pesticides were found to be concentrated by a factor of 100-300 from the rose flowers to the rose absolute. The observed effect of pesticide enrichment was also studied in roses and their extracts from four classically phytosanitary treated fields. Seventeen pesticides were detected in at least one of the extracts. Like the case for the spiked samples in our model, the pesticides present in the rose flowers from Turkey were concentrated in the absolute. Two pesticides, methidathion and chlorpyrifos, were quantified in the rose flowers at approximately 0.01 and 0.01-0.05 mg kg(-1), respectively, depending on the treated field. The concentrations determined for the corresponding rose absolutes were 4.7 mg kg(-1) for methidathion and 0.65-27.25 mg kg(-1) for chlorpyrifos.

  18. Environmental monitoring of the Cea Valduc centre

    International Nuclear Information System (INIS)

    Guetat, Ph.; Jaskula, L.

    2010-01-01

    This paper describes the main features of the environmental control in the vicinity of the CEA Valduc centre, explains the site specific characteristics, the surveillance policy, and some historical elements about tritium atmospheric release. Some levels of activities are given, corresponding to an exposure level below 0.02% of natural irradiation. (author)

  19. Uudised : Guns N' Roses Soomes. Valmis ulmeraadio

    Index Scriptorium Estoniae

    2006-01-01

    Ameerika hard-rock-bändi Guns N' Roses kontserdist 5. juulil Hartwall Areenal Soomes. Kord kuus on Ulmeplaatide kodulehekülel www. ulmeplaadid.ee võimalus kuulata ulmeraadiot, kus esitusel eesti kergemuusika

  20. Use of radiations in rose improvement

    International Nuclear Information System (INIS)

    Desai, B.M.; Abraham, V.

    1978-01-01

    One year old, 250 potted plants of roses in 30 cultivars were irradiated with chronic gamma rays. A dose of about 8 kR of chronic gamma rays was optimum for induction of mutations. A number of morphological abnormalities were observed. A few plants showed changes in petal colour. Three mutants with complete flower colour change were isolated from two cultivars namely Cv. 'Soraya' and Cv. 'Confidence'. Use of ionizing radiation is an effective tool in mutation breeding of roses. (auth.)

  1. In vitro germination of desert rose varieties(

    OpenAIRE

    Tatiane Lemos Varella; Gizelly Mendes Silva; Kaliane Zaira Camacho Maximiliano da Cruz; Andréia Izabel Mikovski; Josué Ribeiro da Silva Nunes; Ilio Fealho Carvalho; Maurecilne Lemes Silva

    2015-01-01

    The drought stress resistance is a characteristic of the desert rose and its estimable beauty flowers, which gave it great relevance in the ornamental market. However, the desert rose production and germination is hampered by possible sterility of their male and female flowers and frequent problems in pollination, so the tissue culture is a promising alternative to the propagation of these plants. This study aimed to evaluate the effect of gibberellic acid on four commercial varieties of dese...

  2. 1999 scientific evaluation at the CEA; L'evaluation scientifique 1999 au CEA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report presents a statement of the scientific and technical activity of the French atomic energy commission (CEA) for the year 1999. This evaluation is made by external and independent experts and requires some specific dispositions for the nuclear protection and safety institute (IPSN) and for the direction of military applications (DAM). The report is divided into 4 parts dealing successively with: 1)the CEA, a public research organization (strategy, research programs, new organization of the CEA activities, civil nuclear research, technology research and transfer, defence activities, transfer of knowledge) 2)the scientific evaluation at the CEA (evaluations of the civil applications of the CEA, IPSN, DAM, INSTN (national institute for nuclear sciences and techniques) 3)synthesis of the 1999 scientific and technical evaluation for each operational directions of the CEA (directions of fuel cycle, of nuclear reactors, of advanced technologies, of materials sciences, of life sciences, of military applications, of the nuclear protection and safety institute and of the national institute for nuclear sciences and techniques) 4)the corresponding members of the evaluation and the list of scientific and technical councils and members.

  3. 1999 scientific evaluation at the CEA; L'evaluation scientifique 1999 au CEA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report presents a statement of the scientific and technical activity of the French atomic energy commission (CEA) for the year 1999. This evaluation is made by external and independent experts and requires some specific dispositions for the nuclear protection and safety institute (IPSN) and for the direction of military applications (DAM). The report is divided into 4 parts dealing successively with: 1)the CEA, a public research organization (strategy, research programs, new organization of the CEA activities, civil nuclear research, technology research and transfer, defence activities, transfer of knowledge) 2)the scientific evaluation at the CEA (evaluations of the civil applications of the CEA, IPSN, DAM, INSTN (national institute for nuclear sciences and techniques) 3)synthesis of the 1999 scientific and technical evaluation for each operational directions of the CEA (directions of fuel cycle, of nuclear reactors, of advanced technologies, of materials sciences, of life sciences, of military applications, of the nuclear protection and safety institute and of the national institute for nuclear sciences and techniques) 4)the corresponding members of the evaluation and the list of scientific and technical councils and members.

  4. Observation on CEA and IL-6 contents in gastric juice

    International Nuclear Information System (INIS)

    Jiang Zhonglin

    2003-01-01

    Objective: To study the changes of CEA and IL-6 contents in blood and gastric juice in patients with gastric cancer and gastritis. Methods: CEA and IL-6 contents in blood and gastric juice were measured with RIA in 60 patients and 30 controls. Results: Gastric juice CEA and IL-6 contents in patients with gastric carcinoma were significantly higher than those in the controls (p < 0.001), however, CEA and IL-6 contents in patients with gastritis and controls were not much different. Conclusion: Gastric juice CEA and IL-6 assay is of diagnostic significance in patients with gastric malignant tumor

  5. Aux marges du monde arabe

    Directory of Open Access Journals (Sweden)

    Hélène Thiollet

    2004-09-01

    Full Text Available L’étude des migrations contemporaines des Érythréens vers le Yémen au tournant des années quatre-vingt-dix permet d’observer les transformations des dynamiques régionales à l’œuvre dans le monde arabe. Les migrations sont un phénomène sensible aux différents aspects (politiques, économiques, culturels, géographiques de l’intégration régionale. Celle si est envisagée dans cet article à travers une approche doublement marginale : -la marginalité géographique de l’Érythrée arabo-africaine et du Yémen, économi­quement isolé dans la péninsule Arabique, -l’étude des migrations formelles et informelles, élément souvent marginal dans l’étude des institutions et des échanges qui constituent un système régional intégré. Cette étude est fondée sur une série d’entretiens menés au Yémen entre février et avril 2002 auprès des administrations yéménites et de la population érythréenne.

  6. L'adaptation aux changements climatiques

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cathy Egan

    plus équitables et plus prospères. Centre de recherches pour le développement international, CP 8500, Ottawa (Ontario) Canada K1G 3H9. Tél. : 613-236-6163 • Télécopieur : 613-238-7230 • Courriel : info@crdi.ca. L'ADAPTATION AUX. CHANGEMENTS CLIMATIQUES. LE RECOURS AUX. ONDES. Les petits exploitants ...

  7. The CEA contribution to quality control

    International Nuclear Information System (INIS)

    Rapin, M.; Colomer, J.

    1979-01-01

    The Commissariat a l'Energie Atomique has developed original methods and techniques for testing delicate components of the primary circuit of pressure water reactors. These techniques make use of a very wide range of non destructive testing methods: Eddy currents, particularly multiple frequencies, for testing steam generator tubes, gudgeon and other pins focused ultrasonics for testing all the welds of the reactor vessel and its cover plate, mixed welds of steam vessels and generators, low welds of the pressurizer and gudgeon pins from the inside. On site use is effected with specific machines intended either for inspecting the tube bundles of steam generators under the responsibility of INTERCONTROLE Co., or for the complete examination of the reactor vessel by mixed CEA/INTERCONTROLE crews under the responsibility of the CEA. All these operations are subjected to a programme of quality assurance that provides the guaranty of execution complying with the procedures in force [fr

  8. The CEA and nuclear energy applications

    International Nuclear Information System (INIS)

    1980-01-01

    With PWR reactors, CEA has applied a large part of its activities on steam generators, whilst other technical studies have involved components, maintenance, thermo-hydraulics, safety, materials, instrumentation apparatus and controls. For small light-water reactors, studies carried out have led to development of the Thermos Project: demonstrating the validity of urban heating derived from a pool-type reactor. Other studies have involved fast reactors (manufacture of fissile fuel assemblies, contributions toward the development of the Superphenix project and longer-term studies involving the overall breeder line). Finally, studies on the retreatment of irradiated fuels: aside from the retreatment of irradiated fuel programmes, CEA is pursuing its work on the TOR Project (large-scale pilot for retreatment of fast-neutron fuels) [fr

  9. Radioimmunodetection of colorectal cancer, using anti-CEA monoclonal antibodies

    International Nuclear Information System (INIS)

    Murayama, Hiroki; Watanabe, Tadashi; Tadokoro, Masanori; Takagi, Hiroshi; Sakuma, Sadayuki; Sakamoto, Junichi.

    1989-01-01

    Aiming at radioimmunodetection of colorectal cancer, anti-CEA monoclonal antibodies (CEA102) were produced by immunization with purified CEA. CEA102 showed high specificity with clorectal cancer by mixed hemadsorption assay and immunoperoxidase technique. The antigen detected by CEA102 was confirmed to be carcinoembryonic antigen (CEA) and its molecular weight was estimated to be ca. 180,000 by biochemical analysis. The in vivo study using nude mice grafted a human colorectal cancer or a human malignant melanoma showed greater accumulation of 125 I-labeled CEA102 in CEA-positive colorectal cancer than in nude mouse tissues and CEA-negative malignant melanoma. Moreover we successfully obtained scans with good localization of the grafted colorectal cancer on FCR (Fuji Computed Radiography). Using 131 I-labeled CEA102 liver metastasis in the patient with colorectal cancer was successfully detected by external scanning with γ-camera. These results suggest that radiolabeled CEA102 is useful for the detection of colorectal cancer. (author)

  10. CA72-4 e CEA no soro e no lavado peritonial de doentes com câncer gástrico CA72-4 and CEA in serum and peritoneal washing in gastric cancer

    Directory of Open Access Journals (Sweden)

    Sandra MANDORWSKI

    2002-03-01

    II and 29 III or IV and 24 patients with benign diseases were studied prospectively. All of them were submitted to laparotomy. Blood and peritoneal washed was collected during surgery before tumoral resection, for determination of CEA and CA72-4. Results - CEA and CA 72-4 serum levels were elevated in 25% and 47,5% respectively. Through the curves ROC, we defined the cut-off values for the markers in washed peritoneal fluid. Through these values CEA and CA72-4 rose in 60% and 57.5% respectively. The values of CEA and of CA 72-4 in the serum and in washed peritoneal fluid were higher in cancer patients stage III and IV. CEA levels in the peritoneal washed fluid were higher in the patients with tumor T3-4. Washed peritoneal CA72-4 differed the control group from the cancer group. Conclusion - CA72-4 was the most sensitive marker in the serum of the patients with gastric cancer. Otherwise in the washing peritoneal fluid the most sensitive marker was CEA. These levels were higher in patients with surpass the serosa and lower in patients with mucosa or muscular tumors.

  11. CEA: assessment of risk management 2011

    International Nuclear Information System (INIS)

    2012-06-01

    This report proposes an overview of CEA activities in the field of risk management in different areas: impact on the environment, installation safety, management of occupational risks (occupational health and safety), radiological protection of workers, transportation of hazardous materials, waste management, protection of sites, installations and heritage, management of emergency situations, management of law risks, controls and audits. It finally presents the risk management department

  12. Population Growth Parameters of Rose Aphid, Macrosiphum rosae (Hemiptera: Aphididae) on Different Rose Cultivars.

    Science.gov (United States)

    Golizadeh, A; Jafari-Behi, V; Razmjou, J; Naseri, B; Hassanpour, M

    2017-02-01

    The rose aphid, Macrosiphum rosae (L.), is one of the most important pests on rose plants (Rosa spp.) with a worldwide distribution. As resistance indices, the development, survivorship, and reproduction of this aphid were evaluated on 10 rose cultivars, including Bella Vita, Cool Water, Dolce Vita, Maroussia, Orange Juice, Pinkpromise, Roulette, Tea, Valentine, and Persian Yellow in laboratory at 25 ± 1°C, 65 ± 5% relative humidity, and photoperiod of 16:8 (L/D) h. Rose aphid successfully survived on all 10 rose cultivars, although mortality rate was higher on Tea and Bella Vita. The number of offspring per female differed significantly among the tested rose cultivars, and ranged from 9.2 on Tea to 38.7 nymphs on Orange Juice. Population growth parameters were significantly affected by rose cultivars. The longest mean generation time (T) was observed on Bella Vita (14.8 days) and Tea (14.7 days) and the shortest on Orange Juice (10.0 days). The net reproductive rate (R 0 ) ranged from 6.9 on Tea to 33.2 nymphs on Orange Juice cultivar. Correspondingly, the highest value of intrinsic rate of increase (r m ) was observed on Orange Juice (0.348 day -1 ) and lower values on Tea (0.131 day -1 ) followed by Bella Vita (0.154 day -1 ). Cluster analysis of all the measured parameters of rose aphid on different rose cultivars revealed that Tea and Bella Vita were relatively resistant to M. rosae. These findings could be useful in developing an integrated pest management (IPM) program for this aphid in urbanized areas and commercial rose potting.

  13. The CEA's waste management strategy; La strategie de gestion des dechets du CEA

    Energy Technology Data Exchange (ETDEWEB)

    Behar, Ch. [CEA Saclay, Dir. de l' Energie Nucleaire, 91 - Gif-sur-Yvette (France); Dall' ava, D. [CEA Saclay, Dir. de l' assainissement et du demantelement nucleaire, 91 - Gif-sur-Yvette (France); Fillion, E. [CEA Fontenay-aux-Roses, Direction de la protection et de la surete nucleaire, 92 (France)

    2011-02-15

    The CEA is tasked with carrying out certain research activities: within the Military Applications Division (DAM), research is focused on the nuclear deterrence and, within the Nuclear Energy Division, on developing the industrial nuclear systems of the future and optimising existing nuclear systems in partnership with EDF and AREVA. These major research and development themes entail a need for nuclear research and support facilities which must be maintained at a high level of performance and safety and, also, constantly upgraded to handle the research activities and programmes for which they are used. The CEA strategy is based on the right packaging of the radioactive liquid or solid waste into a form required for its transport, storage or disposal. The Caraibes software allows an efficient traceability of the waste packages. Most of the radioactive effluent processing stations of CEA are being upgraded

  14. Report transparency and nuclear safety 2007 CEA Grenoble; Rapport transparence et securite nucleaire 2007 CEA Grenoble

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Grenoble for the year 2007. Since 2002 the Passage project aims to realize the decontamination and the dismantling of old nuclear installations of the CEA Grenoble. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the year 2007 saw two main steps of the Passage project: the decommissioning of the Siloette reactor, a public consultation about the Lama laboratory dismantling. (A.L.B.)

  15. Survey of Prunus necrotic ringspot virus in Rose and Its Variability in Rose and Prunus spp.

    Science.gov (United States)

    Moury, B; Cardin, L; Onesto, J P; Candresse, T; Poupet, A

    2001-01-01

    ABSTRACT A survey for viruses in rose propagated in Europe resulted in detection of only Prunus necrotic ringspot virus (PNRSV) among seven viruses screened. Four percent of cut-flower roses from different sources were infected with PNRSV. Progression of the disease under greenhouse conditions was very slow, which should make this virus easy to eradicate through sanitary selection. Comparison of the partial coat protein gene sequences for three representative rose isolates indicated that they do not form a distinct phylogenetic group and show close relations to Prunus spp. isolates. However, a comparison of the reactivity of monoclonal antibodies raised against these isolates showed that the most prevalent PNRSV serotype in rose was different from the most prevalent serotype in Prunus spp. All of the 27 rose isolates tested infected P. persica seedlings, whereas three of the four PNRSV isolates tested from Prunus spp. were poorly infectious in Rosa indica plants. These data suggest adaptation of PNRSV isolates from Prunus spp., but not from rose, to their host plants. The test methodologies developed here to evaluate PNRSV pathogenicity in Prunus spp. and rose could also help to screen for resistant genotypes.

  16. Carcinoembryonic antigen (CEA) level, CEA ratio, and treatment outcome of rectal cancer patients receiving pre-operative chemoradiation and surgery

    International Nuclear Information System (INIS)

    Yang, Kai-Lin; Chang, Shih-Ching; Chu, Lee-Shing; Wang, Ling-Wei; Yang, Shung-Haur; Liang, Wen-Yih; Kuo, Ying-Ju; Lin, Jen-Kou; Lin, Tzu-Chen; Chen, Wei-Shone; Jiang, Jeng-Kae; Wang, Huann-Sheng

    2013-01-01

    To investigate serum carcinoembryonic antigen (CEA) as a prognostic factor for rectal cancer patients receiving pre-operative chemoradiotherapy (CRT). Between 2000 and 2009, 138 patients with advanced rectal cancer receiving CRT before surgery at our hospital were retrospectively classified into 3 groups: pre-CRT CEA <6 ng/ml (group L; n = 87); pre-CRT CEA ≥ 6 ng/ml and post-CRT CEA <6 ng/ml (group H-L; n = 32); and both pre- and post-CRT CEA ≥ 6 ng/ml (group H-H; n = 19). CEA ratio (defined as post-CRT CEA divided by pre-CRT CEA), post-CRT CEA level and other factors were reviewed for prediction of pathologic complete response (pCR). Five-year disease-free survival (DFS) was better in groups L (69.0%) and H-L (74.5%) than in group H-H (44.9%) (p = 0.024). Pathologic complete response was observed in 19.5%, 21.9% and 5.3% of groups L, H-L and H-H respectively (p = 0.281). Multivariate analysis showed that ypN stage and pCR were independent prognostic factors for DFS and that post-CRT CEA level was independently predictive of pCR. As a whole, post-CRT CEA <2.61 ng/ml predicted pCR (sensitivity 76.0%; specificity 58.4%). For those with pre-CRT CEA ≥6 ng/ml, post-CRT CEA and CEA ratio both predicted pCR (sensitivity 87.5%, specificity 76.7%). In patients with pre-CRT serum CEA ≥6 ng/ml, those with “normalized” CEA levels after CRT may have similar DFS to those with “normal” (<6 ng/ml) pre-CRT values. Post-CRT CEA level is a predictor for pCR, especially in those with pre-CRT CEA ≥6 ng/ml

  17. The Rose Report [Continued]: "The Invisible Worm"

    Science.gov (United States)

    Drummond, Mary Jane

    2009-01-01

    While Colin Richards' article is a trenchant analysis of the big themes and missed opportunities of the Rose Report, this response examines some of the small print. It concludes that the document is disfigured by many minor blemishes, and is also fatally flawed by a crude misapprehension of the nature of progress and the purpose of education.

  18. Where Is the Next Rose Director?

    OpenAIRE

    John Blundell

    2013-01-01

    Rose Friedman (née Director), the Chicago-trained economist, was a very important contributor to Milton Friedman’s scholarly output, popular writings, and television series. His remarkable role in society was to a significant extent a joint role from which she cannot be separated.

  19. Gamma irradiation studies on garden roses

    International Nuclear Information System (INIS)

    Deepti; Datta, S.K.

    1999-01-01

    Differential sensitivity with respect to sprouting, survival, plant height and morphological abnormalities were recorded in a gamma ray induced breeding programme with four cultivars of garden roses. Somatic mutations in flower colour/ shape were detected as chimera in three cultivars. Attempts are being made to isolate the mutant tissues in pure form. (author)

  20. History of enrichment research at the CEA

    International Nuclear Information System (INIS)

    Camarcat, N.

    1996-01-01

    French researches about uranium enrichment have been carried out at the CEA for about 40 years. In the beginning, these researches were considered as marginal and were carried out by a small team from the Powders Central Laboratory. They became intensive since 1955 and culminated in 1967 with the conception of Pierrelatte's factory. Several processes were studied: the gaseous diffusion, the chemical treatments, the centrifugation, the laser and electromagnetic separation processes on atomic and molecular vapors. Only a few of them were fully developed. This paper summarizes the development of these different processes in their historical context. (J.S.). 1 fig

  1. Status of Cea spallation modules for ads

    International Nuclear Information System (INIS)

    Enderle, R.; Poitevin, Y.; Deffain, J.P.; Bergeron, J.

    2001-01-01

    In the framework of CEA studies on ADS dedicated to waste transmutation, a liquid metal reference concept and an alternative solid target have been evaluated to produce neutrons inside the spallation module. This work examines the design (neutronic, thermohydraulic and mechanical aspects) and the performances of both options. It is shown that a liquid Pb-Bi target offers more possibilities regarding to high protons current densities (possible industrial extrapolation) but that a solid target made with tungsten particles offers also interesting ability to create a neutrons flux appropriated (strong spectrum and flat axial distribution) to an sub-critical core dedicated to incineration. (author)

  2. Press tour Siloe CEA/GRENOBLE; Voyage de presse Siloe CEA/GRENOBLE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The experimental reactor, Siloe, has been stopped the 23 december 1997. This paper of the Cea Grenoble, presents the historical aspects of this reactor and its missions. It gives then a global description of the stopping and dismantling procedure, with the planning, the financing and the human impacts of the operation. The wastes management is also takes into account. (A.L.B.)

  3. The CEA program on boiling noise detection

    International Nuclear Information System (INIS)

    Le Guillou, G.; Brunet, M.; Girard, J.P.; Flory, D.

    1982-01-01

    The research program on the application of noise analysis on boiling detection in a fast subassembly began 10 years ago at the CEA, mainly in the Nuclear Center of Cadarache. Referring exclusively to the aspects of premature detection of the boiling phenomenon it can be said that this program is organized around the following three detection techniques: acoustic noise analysis; neutron noise analysis; temperature noise analysis. Its development is in conjunction with in-pile experiments in Phenix or Rapsodie as well as 'ex-pile' (boiling experiments through electric heating). Three detection techniques were developed independent of each other, but that they were regrouped during the execution of the most important experiments and with the 'Super Phenix' project. The noise analysis system ANABEL with which Superphenix will be equipped with shows the industrial interest in detection methods based on noises. One of the results of the CEA program today is the possibility to evaluate the potential capacity for boiling detection in the subassembly. But in order to obtain the necessary funds from the commercial nuclear plant operators it is mandatory to have successful demonstrations which will be the objective of the future program

  4. Cutoff Values of Serum Carcinoembryonic Antigen (CEA) in Normal Korean Adults and Factors Influencing Serum CEA Level

    International Nuclear Information System (INIS)

    Kim, Jong Soon; Kim, Sun Wook; Chung, June Key; Lee, Dong Soo

    1994-01-01

    Carcinoembryonic Antigen is one of most frequently checked tumor markers in cancer management. We performed statistical analysis with serum CEA data of 2626 persons who received regular health examination and were thought to be free of active disease to determine the cutoff values of serum CEA level in normal Korean adults and to study the factors influencing serum CEA levels in normal subjects. 1) The cutoff values of serum CEA in normal Korean adults in general were 9.28 ng/ml for men, 5.90 ng/ml for women. 2) Serum CEA level was influenced by age, present smoking history, sex, and abnormal findings in chest X ray. 3) Serum CEA level had no correlation with the history of amount of alcohol consumption or obesity. 4) Cutoff values of serum CEA in normal Korean adults were tabulated according to age, sex, and smoking history. Serum CEA level was influenced by age, sex, present smoking history and abnormal findings in chest X ray and cutoff values of serum CEA were tabulated according to age, sex, and smoking history.

  5. Solar drying of rose (Rosa sp.) petals

    Energy Technology Data Exchange (ETDEWEB)

    Balladin, D.A.; Headley, Oliver [University of the West Indies, Center for Resource Management and Environmental Studies, St. Michael (Barbados)

    1999-10-01

    The rose (Rosa sp.) petals can be dried after 2 days at about 30degC reaching an equilibrium moisture content after 16 h using the solar wire basket dryer. The initial moisture content (wet wt basis) and final moisture content (dry wt basis), determined by the Dean-Stark toluene were 65.7 and 25.2% respectively. The intensity of the rose red coloured pigment (pelargonidin) decreased by a factor of 2.5 after drying. The pelargonidin ethanoic extract as an acid-base indicator, has a K{sub 4} value of 1 x 10{sup -4} mol 1{sup -1} and pH of end point 4 and imbibed on filter paper and allowed to air dry for 5 min showed excellent properties as acid-based test tapes. (Author)

  6. Bourse du CRDI aux chercheurs candidats au doctorat 2017 | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cet appel à propositions s'adresse aux citoyens canadiens, aux résidents permanents du Canada et aux citoyens de pays en développement inscrits au doctorat dans une université canadienne. Qui peut présenter une demande. Pour être admissible, vous devez remplir les conditions suivantes : Être citoyen canadien ou ...

  7. ROSEE cleans up after the Cold War

    International Nuclear Information System (INIS)

    Valenti, M.

    1994-01-01

    This article describes a robot named ROSEE, designed by engineers at the DOE's Hanford site to minimize the risk of radiation exposure to workers cleaning up to residue left by America's manufacture of nuclear weapons. ROSEE is the acronym for Remotely Operated Sediment Extraction Equipment, a robot designed to vacuum sediment and debris from a nuclear fuels storage pool at the Department of Energy's Hanford nuclear waste storage site in Richland, Wash. The task facing ROSEE involves cleaning out the N basin at Hanford. Work is schedules to begin before the fall. The basin houses nuclear fuel refined during 24 years of the Cold War era. This water-filled structure is 24 feet deep, 87 feet long, and 56 feet wide, approximately three times larger than an Olympic-size swimming pool. Nuclear fuel was contained in honeycomb cells mounted 1 inch from the bottom of the pool. The cells rise 10 feet from the bottom of the basin, and each cell is 21 inches deep and 14 inches wide. The cells now hold radioactive residues that must be removed for final safe disposal

  8. Mapping a new black spot resistance locus in rose [abstract

    Science.gov (United States)

    Rose black spot, caused by Diplocarpon rosae, is one of the most devastating foliar diseases of cultivated roses (Rosa hybrida). The pathogen is globally distributed and has the potential to cause large economic losses in the outdoor rose industry. Genetic resistance is the most economical disease m...

  9. Downy mildew: a serious disease threat to rose health worldwide

    Science.gov (United States)

    Peronospora sparsa is a downy mildew-causing oomycete that can infect roses, blackberries and other members of the rose family. During the last 20 years, this disease has become a serious problem for rose growers in the U.S. and worldwide. While much is known about the disease and its treatment, inc...

  10. Marantáceas Nuevas de Colombia

    Directory of Open Access Journals (Sweden)

    Smith Lyman B.

    1948-06-01

    Full Text Available Identificando numeroso material botánico en el United States National Herbarium, hemos hallado varias especies de la familia Marantaceae, especialmente de Colombia, que todavía no han sido descritas. No intentamos tratar sobre todas ellas en el presente trabajo, sino que nos limitamos a describir las más notables, dejando las demás para un estudio posterior, cuando se disponga de material más completo. Para poder entender con exactitud la estructura de las brácteas menores, así como de los pétalos y el androceo de estas plantas, no obstante lo mucho que se puede averiguar con ejemplares secos de herbario, es necesario que las observaciones se hagan sobre material vivo. La necesidad de estudiar en vivo las Marantáceas es mayor que En la gran mayoría de las familias que componen las Fanerógamas.

  11. CEA programme on gas cooled reactors

    International Nuclear Information System (INIS)

    Carre, F.; Fiorini, G.L.; Chapelot, Ph.; Gauthier, J.C.

    2002-01-01

    Future nuclear energy systems studies conducted by the CEA aim at investigating and developing promising technologies for future reactors, fuels and fuel cycles, for nuclear power to play a major part in sustainable energy policies. Reactors and fuel cycles are considered as integral parts of a nuclear system to be optimised as a whole. Major goals assigned to future nuclear energy systems are the following: reinforced economic competitiveness with other electricity generation means, with a special emphasis on reducing the investment cost; enhanced reliability and safety, through an improved management of reactor operation in normal and abnormal plant conditions; minimum production of long lived radioactive waste; resource saving through an effective and flexible use of the available resources of fissile and fertile materials; enhanced resistance to proliferation risks. The three latter goals are essential for the sustainability of nuclear energy in the long term. Additional considerations such as the potentialities for other applications than electricity generation (co-generation, production of hydrogen, sea water desalination) take on an increasing importance. Sustainability goals call for fast neutron spectra (to transmute nuclear waste and to breed fertile fuel) and for recycling actinides from the spent fuel (plutonium and minor actinides). New applications and economic competitiveness call for high temperature technologies (850 deg C), that afford high conversion efficiencies and hence less radioactive waste production and discharged heat. These orientations call for breakthroughs beyond light water reactors. Therefore, as a result of a screening review of candidate technologies, the CEA has selected an innovative concept of high temperature gas cooled reactor with a fast neutron spectrum, robust refractory fuel, direct conversion with a gas turbine, and integrated on-site fuel cycle as a promising system for a sustainable energy development. This objective

  12. The Grenoble CEA Center: dismantled and rehabilitated

    International Nuclear Information System (INIS)

    Anon.

    2013-01-01

    The denuclearization program of the CEA center in Grenoble was launched in 2001. It involves 6 nuclear facilities (3 research reactors: Melusine, Siloette, and Siloe, and 1 laboratory (LAMA) and 2 units for processing wastes). The dismantling works were finished at the end of 2012 and the 2013 program concerns: the demolition of the buildings homing Melusine and Siloe reactors, the final rehabilitation of the Siloe raft, and the final rehabilitation of the laboratory and of the waste processing units. The budget is 117*10 6 euros for Siloe, 28*10 6 euros for Melusine, 6*10 6 euros for Siloette, 70*10 6 euros for the LAMA, and 90*10 6 euros for the 2 waste processing units. (A.C.)

  13. Alpha waste incinerator at the Cea Valduc

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    The Cea/Valduc has brought into operation an incinerator for alpha waste. The incineration is in two steps. The first one is a pyrolysis under reduction atmosphere in a furnace at 550 celsius degrees and the second one is a calcination under oxidizing atmosphere of the pyrolysis residue in a furnace at 900 celsius degrees. The ashes have less than 1% of carbon. The gas coming from incineration become oxidized at 1100 Celsius degrees, then are cooled, filtered to eliminate any track of radioactivity. Then, they are cleaned with a neutralisation process. The facility reduces the volume of waste in a factor 20. The capacity of treatment is 7 kg/h. The annual capacity is 30 m 3 . The investment represents 70 millions of francs and the cost of functioning is 2 M F by year. (N.C.)

  14. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer

    DEFF Research Database (Denmark)

    Knudsen, Mie Grunnet; Sorensen, J B

    2012-01-01

    The use of CEA as a prognostic and predictive marker in patients with lung cancer is widely debated. The aim of this review was to evaluate the results from studies made on this subject. Using the search words "CEA", "tumor markers in lung cancer", "prognostic significance", "diagnostic...... significance" and "predictive significance", a search was carried out on PubMed. Exclusion criteria was articles never published in English, articles before 1981 and articles evaluating tumor markers in lung cancer not involving CEA. Initially 217 articles were found, and 34 were left after selecting those...... relevant for the present study. Four of these included both Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC) patients, and 31 dealt solely with NSCLC patients. Regarding SCLC no studies showed that serum level of CEA was a prognostic marker for overall survival (OS). The use of CEA...

  15. Obituary: William K. Rose (1935-2010)

    Science.gov (United States)

    Trimble, Virginia

    2011-12-01

    Stellar astrophysicist William Kenneth Rose died near his home in Potomac, Maryland, on September 30, 2010, after an extended illness. Rose was the son of pharmacist Kenneth William Rose and Shirley Near Rose and was born in Ossining, New York, on August 10, 1935. He received an AB from Columbia College in 1957 and a PhD in physics from Columbia University in 1963, with a thesis on "measurements of linear polarization in discrete radio sources using a 9.4 cm maser," under the direction of Charles H. Townes. Rose played a major role in designing and constructing the maser and used it at a radio telescope at Maryland Point that belonged to the Naval Research Lab. He observed Jupiter and Saturn and a number of extra-solar-system sources, and also diffuse centimeter emission (see appendix). The thesis was not published in an archival journal, but can be found under Library of Congress code QB 475.R67. While in graduate School, Bill married Sheila Tuchman, whose primary scientific interests were biological. None of their three children chose to be scientists, but two are CPAs. Bill moved successfully through the academic hurdles) from a research position at Princeton (1963-67), where a collaboration with Nick Woolf and Martin Schwarzchild on the infrared spectra of giant stars became one of his most-cited papers, to assistant and associate professorships at MIT (1967-71), and then associate and full professorships at the University of Maryland (1971 to retirement in 2005). His most innovative work was probably that on nova explosions arising from degenerate ignition of hydrogen accreted on white dwarfs in close binary systems, published in 1968. The same idea occurred to others at about the same time, and Bill did not, perhaps, get quite his fair share of the credit. I first met Sheila and Bill in summer 1969 at the Stony Brook summer school on stellar evolution (not published until 1972). He lectured on the nature of nova explosions and on nuclear burning in thin

  16. Report transparency and nuclear safety 2007 CEA Saclay; Rapport transparence et securite nucleaire 2007 CEA Saclay

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Saclay for the year 2007. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially two public consultation on release authorizations and the Neurospin installations, the dismantling of the 49 nuclear installation, the shutdown of the learning reactor ULYSSE are detailed. (A.L.B.)

  17. Report transparency and nuclear safety 2007 CEA Cadarache; Rapport transparence et securite nucleaire 2007 CEA Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Cadarache for the year 2007. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the report discusses the beginning of the RJH reactor construction, the fourth generation reactors research programs, the implementing of la Rotonde the new radioactive wastes management installation, the renovation of the LECA. (A.L.B.)

  18. Report transparency and nuclear safety 2007 CEA Marcoule; Rapport transparence et securite nucleaire 2007 CEA Marcoule

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Marcoule for the year 2007. Since its creation in 1955 the center realizes industrial and scientific activities relative to the civil and military applications of the radioactivity. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the following two base activities are detailed: Atalante and Phenix. (A.L.B.)

  19. CEA monitoring of palliative treatment for colorectal carcinoma.

    Science.gov (United States)

    Herrera, M A; Chu, T M; Holyoke, E D; Mittelman, A

    1977-01-01

    Palliative treatment was applied to 131 cases of unresectable or palliatively resected colorectal carcinoma being monitored with serial CEA determinations. There were 84 instances of disease progression with 67 (80%) of them showing an increase in CEA above pretreatment levels or maintaining high levels, and 17 (20%) showing a fall when compared to pretreatment values or maintaining low initial values. There was a clear-cut regression of the disease in only 9 instances. In all 9, the CEA clearly dropped or maintained low valles throughout the period of regression. No patient in regression had a rise or maintained an elevated CEA level. These changes in CEA followed closely the clinical response of our patient to the use of a particular agent, although for the Nitrosourea compounds there may be a tendency to lower the CEA regardless of the patient's tumor response to the drug. This could be due to the fact that the Nitrosoureas produce a diffuse block of cellular activity, both at the nucleous and cytoplasm; while other compounds act as alkylating agents or by inhibition of enzymes involved in the metabolism of nucleic acids (i.e., 5-FU inhibiting thymidylate synthetase). In general, longer survival was found in those patients who had initially lower levels of CEA as compared to those with high initial levels. The patients with a favorable CEA response to the treatment (falling CEA or maintained low value), even in many who did not show a clinical response had a longer survival than the group with rising or stable high levels. The main value in CEA monitoring of patients resides in its correlation with the amount of disease present and then its ability to detect progression of tumor mass which is not clinically measurable. PMID:64132

  20. Analysis of desert rose using PIXE and RBS techniques

    International Nuclear Information System (INIS)

    Al-Kofahi, M.M.; Hallak, A.B.; Al-Juwair, H.A.; Saafin, A.K.

    1993-01-01

    Particle-induced x-ray emission (PIXE) and Rutherford backscattering spectrometry (RBS) were used to analyse desert rose geological samples. Samples from the rose core and from the rose peripherals were studied. All samples were found to contain C, N, O, Na, Mg, Si, S, Cl, K, Ca, Ti, Mn, Fe and Sr. Core samples were found to contain more silicon than peripheral samples. The extra silicon in the rose core may suggest a mechanism for the formation of the rose through crystal growth on a seed of silicon. (author)

  1. Extraction of Rose Bengal into chloroform

    International Nuclear Information System (INIS)

    Lengyel, J.; Vecernik, J.; Krtil, J.

    1982-01-01

    The paper describes the extraction of Rose Bengal (RB)into chloroform. A radiometric method with the aid of 131 Ilabelled RB was used. The efficiency of the extraction in dependence on pH and RB concentration was studied. For the interpretation of the extraction data the values of pK 1 and pK 2 of RB were determined spectrophotometrical-ly and potentiometrically. A mechanism for the RB extraction into chloroform on the basis of IR measurements is proposed. (author)

  2. Aux origines de la science moderne

    CERN Document Server

    Rossi, Paolo

    1999-01-01

    Aux origines de la science moderne. " Lorsque l'on aborde l'étude d'une pensée qui n'est plus la nôtre, il est important de chercher à oublier ce que nous savons ou croyons savoir. " Pour appréhender cette période fondatrice que fut la Révolution scientifique du XVIIe siècle en Europe, Paolo Rossi nous replonge dans des atmosphères intellectuelles et des modes de pensée depuis longtemps disparus. Des secrets hermétiques aux calculs mathématiques, de la magie au magnétisme et des cabinets de curiosité aux premières académies des sciences défilent ainsi des notions et des individus qui, remis en toute simplicité dans le contexte de leur époque, retrouvent une épaisseur et un sens nouveaux. Ainsi racontée sous la forme d'une histoire des idées, l'histoire des sciences devient accessible à tous.

  3. L'Anse Aux Meadows, Newfoundland

    Science.gov (United States)

    2008-01-01

    L'Anse aux Meadows is a site on the northernmost tip of the island of Newfoundland, located in the Province of Newfoundland and Labrador, Canada, where the remains of a Viking village were discovered in 1960 by the Norwegians Helge and Anne Ingstad. The only authenticated Viking settlement in North America outside Greenland, it was the site of a multi-year archaeological dig that found dwellings, tools and implements that verified its time frame. The settlement, dating more than five hundred years before Christopher Columbus, contains the earliest European structures in North America. Named a World Heritage site by UNESCO, it is thought by many to be the semi-legendary 'Vinland' settlement of explorer Leif Ericson around AD 1000. The settlement at L'Anse aux Meadows consisted of at least eight buildings, including a forge and smelter, and a lumber yard that supported a shipyard. The largest house measured 28.8 by 15.6 m and consisted of several rooms. Sewing and knitting tools found at the site indicate women were present at L'Anse aux Meadows The image was acquired on September 14, 2007, covers an area of 14.2 x 14.6 km, and is located at 51.5 degrees north latitude, 55.6 degrees west longitude. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  4. Annual progress report of the Fontenay-aux-Roses Research Group. January 1 to December 31, 1976

    International Nuclear Information System (INIS)

    The program of exploitation of TFR 400 consisted in two main research subjects: energy balance in the discharges of TFR 400 and the development of heating technics (neutral injection and cyclotron heating). Theoretical studies on Tokamak physics, enhanced by numerical simulation, were especially concerned with the thermal conductivity of electrons, impurity transport, MHD breakdown instabilities, and the plasma turbulence. Some ion sources (duopigatron) and neutral injectors (periplasmatron) were developed. The TFR 600 program started with some works on new TFR parts (the vacuum chamber) and heating improvement (neutral injection and also granion injection in INGRA). Detailed design studies and tests relating to the 'TORE II' project continued. Researches under contract effected for JET were concerned with reliability and the vacuum chamber and mechanical structures [fr

  5. Annual progress report of the Fontenay-aux-Roses Research Group. January 1 to December 31 1978

    International Nuclear Information System (INIS)

    Within the context of the TFR programme, the problem of balance again filled a significant place in 1978. The 1978 work resulted in partial successes only from the practical angle by ensuring long discharges of 150 to 200 KA, but they made it possible to reach a comprehensive understanding of the problem by using a sophisticated digital model that is a very good representation of the change in the plasma connected to outside circuits. Despite some technical difficulties, it was fortunately possible to obtain fine results on the ionic cyclotron heating. Significant progress was made in the field of diagnoses, particularly local temperature measurements and resolved with time which are so important for the development of heating methods and for the studies of pure physics. With the improvements also made in the other domains, TFR once more possesses a panoply of diagnoses that has not many equals. Another important event was the order for nine sources of the circular periplasmatron type by the I.P.P. of Garching to fit out the neutral injection lines of ASDEX. In the area of neutrals, the development work on JET, being pursued vigorously, should also be noted. Then there is also the franco-sovietic cooperation work with Tl0, particularly for the measurement of the electronic temperature by cyclotronic emission. Last, the TFR 604 and TORE II projects have undergone some change, the first with respect to the injection of 4MW tangential neutrals into the plasma and the second concerning the use of superconducting coils (TORE II SUPRA version) to create the toroidal field [fr

  6. Annual progress report of the Fontenay-aux-Roses Research group. January 1 to December 31, 1979

    International Nuclear Information System (INIS)

    1980-01-01

    The main theoretical and numerical studies in 1979 concerned MHD equilibrium and stability, turbulence and transport phenomena as well as non-linear phenomena and micro-instabilities. In addition, the waves in plasmas and spectroscopy were also studied as was the digital simulation of heating with the aid of the MAKOKOT code. The experimental pogramme relating to TFR 600 is being pursued. Results have been achieved in the fields of high frequency heating and by the injection of neutrals and in that of the equilibrium and stability of the discharge. The TORE 2 SUPRA project was the subject of research for technical solutions on the use of superfluid helium-cooled superconductors. With regard to JET, five different diagnosis systems were examined as well as heating by injecting neutrals and by ionic cyclotronic wave [fr

  7. The organisation of criticality hazard prevention at the CEA

    International Nuclear Information System (INIS)

    Mijuin, Dominique; Carros, Helene; Sevestre, Bernard

    2003-01-01

    This paper deals with the organisation of criticality hazard prevention at the French Atomic Energy Commission (CEA). This new organization has been experimented since the end of year 2000. During the first semester of year 2002, the CEA nuclear inspection team, who is in charge of the control function at the CEA general administration level, has performed an inquiry to check the effectiveness of the new organization. The conclusions of this inquiry are very positive; a few recommendations are now taken in to account to further improve the efficiency of this organization. (J.P.N.)

  8. Using Rose and Compass for Authentication

    International Nuclear Information System (INIS)

    White, G.

    2009-01-01

    Many recent non-proliferation software projects include a software authentication component. In this context, 'authentication' is defined as determining that a software package performs only its intended purpose and performs that purpose correctly and reliably over many years. In addition to visual inspection by knowledgeable computer scientists, automated tools are needed to highlight suspicious code constructs both to aid the visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary, and have limited extensibility. An open-source, extensible tool can be customized to the unique needs of each project. ROSE is an LLNL-developed robust source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C, C++, and FORTRAN. It continues to be extended to support the automated analysis of binaries (x86, ARM, and PowerPC). We continue to extend ROSE to address a number of security specific requirements and apply it to software authentication for non-proliferation projects. We will give an update on the status of our work

  9. Using Rose and Compass for Authentication

    Energy Technology Data Exchange (ETDEWEB)

    White, G

    2009-07-09

    Many recent non-proliferation software projects include a software authentication component. In this context, 'authentication' is defined as determining that a software package performs only its intended purpose and performs that purpose correctly and reliably over many years. In addition to visual inspection by knowledgeable computer scientists, automated tools are needed to highlight suspicious code constructs both to aid the visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary, and have limited extensibility. An open-source, extensible tool can be customized to the unique needs of each project. ROSE is an LLNL-developed robust source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C, C++, and FORTRAN. It continues to be extended to support the automated analysis of binaries (x86, ARM, and PowerPC). We continue to extend ROSE to address a number of security specific requirements and apply it to software authentication for non-proliferation projects. We will give an update on the status of our work.

  10. CEA celebrates the jubilee of ZOE reactor

    International Nuclear Information System (INIS)

    Loverini, M.J.

    1998-01-01

    This article reviews the saga of the first French nuclear reactor ZOE. As soon as 1939 Frederic Joliot had an intuition of the possibility of using fissioning nuclei to produce energy. 3 patents describing the concept of a nuclear reactor highlighting the role of natural uranium as fuel, heavy water as moderator, were registered. The only producer in the world of heavy water was a Norwegian firm, a fierce competition with Germany for the control of deuterium broke out. Eventually 185 Kg of heavy water were secretly convoyed in Great-britain. Because of the development of the war, the small scientist team in charge of the project has had to move from France to Great-britain then to Canada. At the end of the war, the 'Commissariat a l'energie atomique' (CEA) was created, its first aim was to design a nuclear reactor as soon as possible. In 1948 the first criticality of ZOE is reached, 6 years later than the team led by Enrico Fermi did in Chicago. In 1976 ZOE was decommissioned and is now a small museum dedicated to nuclear energy. (A.C.)

  11. Carcinoembryonic antigen (CEA) dynamics in stomach cancer patients receiving cryotherapy

    International Nuclear Information System (INIS)

    Myasoedov, D.V.; Krupka, I.N.; V'yunitskaya, L.V.

    1986-01-01

    Radioimmunologic assays of blood serum carcinoembryonic antigen (CEA) level were conducted at major stages of treatment of gastric cancer by subtotal stomach resection and gastrectomy with preliminary cryotreatment and thawing of tumor. A short-term rise in CEA level occurred in 53.9 % of cases 3-4 days after combined therapy. A decrease in CEA concentration at discharge from hospital as compared with preoperative level and that registered 3-4 days after operation was observed in 50 and 75 % of cases of combined therapy, respectively, and 47.5 and 37.5 % of controls (surgery without cryotreatment). There was nocorrelation between cryotreatment and changes in CEA level in gastric ulcer patients

  12. Fifty years of particle physics at the CEA

    International Nuclear Information System (INIS)

    Turlay, R.

    1997-01-01

    A historical review of researches at the CEA (and more particularly at Saclay) in particle physics, is presented. Contributions in themes such as polarized targets, bubble chambers, classic and superconductive magnets, etc. resulted in cooperation to the design of various machines such as Van de Graaff accelerator, cyclotron, Saturne, etc. Collaborations between CEA and CERN had led to numerous experiments in high energy physics, such as electronic experiments with the SPS accelerator. CEA was also involved in the intermediate boson discovery on the SppS collision apparatus, and is participating in two CERN's programs, neutrino physics (NOMAD) and CP violation (NA48). CEA is also collaborating with Russian, German and American laboratories in these domains

  13. Management and storage of spent fuel from CEA research reactors

    International Nuclear Information System (INIS)

    Merchie, F.

    1996-01-01

    CEA research reactors and their interim spent fuel storage facilities are described. Long-term solutions for spent fuel storage problems, involving wet storage at PEGASE or dry storage at CASCAD, are outlined in some detail. (author)

  14. Nuclear energy in France. Respective part of CEA, EDF, FRAMATOME

    International Nuclear Information System (INIS)

    Graf, J.J.

    1976-01-01

    In France, the three actors on the nuclear stage are CEA, EDF, and industry. The CEA, important organism of research and development, represents the public power, counsels the Government for safety and constitutes the State interference by the indirect mean of budget which is assigned to it. The industry, FRAMATOME, is commissioned to build plants. EDF has vocation to provide electricity at the lower costs [fr

  15. Balance 2003 of the risks control at the Cea

    International Nuclear Information System (INIS)

    2004-07-01

    As a research center on the energy, the information and health technologies and the defense, the Cea activities are indissociable from the risk control notion. To organize the risks management, the Cea decided to create in july 2003 a special pole of risks control and management. This presentation is based on some major topics of the risks control: the environmental impact control, the occupational risks control, the installations safety control and the hazardous matter transport control. (A.L.B.)

  16. In vitro germination of desert rose varieties(

    Directory of Open Access Journals (Sweden)

    Tatiane Lemos Varella

    2015-08-01

    Full Text Available The drought stress resistance is a characteristic of the desert rose and its estimable beauty flowers, which gave it great relevance in the ornamental market. However, the desert rose production and germination is hampered by possible sterility of their male and female flowers and frequent problems in pollination, so the tissue culture is a promising alternative to the propagation of these plants. This study aimed to evaluate the effect of gibberellic acid on four commercial varieties of desert rose (Adenium obesum cultivated in vitro. The seeds of the varieties ‘Orange Pallet’, ‘Carnation violet’, ‘Diamond ring’ and ‘Vermiliont’ were sterilized and inoculated on Water + Agar (T0, medium MS (T1, ½ MS (T2, MS + 0.25 mg L-1 GA3 (T3, MS + 0.5 mg L-1 GA3 (T4, ½ MS + 0.25 mg L-1 GA3 (T5, ½ MS 0.5 mg L-1 GA3 (T6. The seeds germination of A. obesum was initiated on the fourth day of cultivation and on the tenth day was possible to observe the expansion of the cotyledons and leaf expansion with subsequent development of early secondary root. The ‘Orange pallet’ variety germinated 100% of seeds on water + agar and MS ½ + 0.5 mg L-1 of GA3. For ‘Diamond Ring’ and ‘Carnation violet’ the highest rate of germination occurred in treatments MS ½; 0.25 mg L-1 GA3; MS + 0.5 mg L-1 GA3 MS ½ + 0.5 mg L-1 GA3 averaging 80% and 70%, respectively. For ‘Vermiliont’ the best response was in MS and MS ½ + 0.5 mg L-1 GA3 ranging between 70-90% germinated embryos. It was registered different malformations in all treatments like absence of roots and apexes during seedling development. The concentrations of GA3 did not affect significantly the seed germination.

  17. Healing incisional surgical wounds using Rose Hip oil in rats

    OpenAIRE

    Lainy Carollyne da Costa Cavalcante; Thyago Cezar Prado Pessôa; Rubens Fernando Gonçalves Ribeiro Júnior; Edson Yuzur Yasojima; Rosa Helena de Figueiredo Chaves Soares; Marcus Vinicius Henriques Brito; Eduardo Henrique Herbster Gouveia; Lucas Nascimento Galvão; Suzana Rodrigues Ramos; Adan Kristian Almeida Carneiro; Yuri Aarão Amaral Serruya; Mateus Malta de Moraes

    2017-01-01

    Purpose: To evaluate incisional surgical wound healing in rats by using Rose Hip (Rosa rubiginosa L.) oil. Methods: Twenty-one days after the oophorectomy procedure, twenty-seven female, adult, Wistar rats were distributed into three groups: Control group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Rose Hip group (wound treatment with Rose Hip oil). Each group was distributed according to the date of euthanasia: 7, 14 and 21 days. ...

  18. Administration des subventions aux institutions Dépenses de projet ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Consultants. Cette catégorie comprend toutes les dépenses engagées pour retenir les services d'un consultant aux ... déplacement, d'hébergement et de subsistance, ainsi qu'aux services de soutien retenus directement ... le transport aérien et les autres dépenses afférentes aux déplacements du personnel du projet à.

  19. ECR Light Ion Sources at CEA/Saclay%CEA/Saclay的ECR轻离子离子源

    Institute of Scientific and Technical Information of China (English)

    R.Gobin; P-A.Leroy; O.Tuske; D.Uriot; P-Y.Beauvais; A.Ben Ismail; D.Bogard; O.Delferriere; D.de Menezes; R.Duperrier; Y.Gauthier; F.Harrault

    2007-01-01

    In the beginning of the 90s,T.Taylor and his collaborators demonstrated ECR sources operating at low frequency (I.e.2.45GHz) are able to produce very intense single charge light ion beams.At CEA/Saclay,the SILHI source developments started in 1995.Since 1997 more than 100mA proton or deuteron beams are routinely produced in pulsed or continuous mode.To comply with ADS reliability constraint,important improvements have been performed to increase the installation reliability.Moreover,to optimize the beam transport in the low energy beam line,the extraction system was carefully designed and space charge compensation studies were undertaken.An important step has been reached in 2005 with the development of a permanent magnet source able to produce a total beam of 109mA at 85kV.A new test bench named BETSI,especially dedicated to permanent magnet source developments,is presently under construction.It will allow analysing positive or negative extracted beams up to 50keV and 100mA.In addition,for several years work has been done to optimize the production of negative hydrogen ion beam with such an ECR source.Recent analysis pushed towards the construction of a new set up based on a multicusp magnetic configuration.After a brief overview of the CEA/Saclay source developments,this article will point out on the recent results and present status.

  20. Big reorganisation at the CEA; [structural reorganisation and reform of management methods within the CEA; CEA document on civil nuclear energy policy research

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Following the recommendations of a report prepared by the Director General, CEA is to be reorganised to clarify the division of responsibility within the CEA and to increase its adaptability and openness to the outside world. The management structures have been simplified and two large institutes of the Commissariat, the Institute of Industrial Research and Development and the Institute of Fundamental Research have been disbanded and their activities reallocated to six smaller operational directorates. Seven functional directorates have been created to cover communications, finance, defence issues, manpower, international relations, planning and secretariat. An outline of the new structure is given and explained. (UK)

  1. The compass rose pattern in electricity prices.

    Science.gov (United States)

    Batten, Jonathan A; Hamada, Mahmoud

    2009-12-01

    The "compass rose pattern" is known to appear in the phase portraits, or scatter diagrams, of the high-frequency returns of financial series. We first show that this pattern is also present in the returns of spot electricity prices. Early researchers investigating these phenomena hoped that these patterns signaled the presence of rich dynamics, possibly chaotic or fractal in nature. Although there is a definite autoregressive and conditional heteroscedasticity structure in electricity returns, we find that after simple filtering no pattern remains. While the series is non-normal in terms of their distribution and statistical tests fail to identify significant chaos, there is evidence of fractal structures in periodic price returns when measured over the trading day. The phase diagram of the filtered returns provides a useful visual check on independence, a property necessary for pricing and trading derivatives and portfolio construction, as well as providing useful insights into the market dynamics.

  2. Bivalent fragment of the ior-CEA1 antibody. A challenge to the positive CEA tumors radioimmunotherapy

    International Nuclear Information System (INIS)

    Ravelo, Rolando; Sanchez, Iradia; Pimentel, Gilmara; Oliva, Juan; Perez, Lincidio; Ayala, Marta; Bell, Hansell; Gavilondo, Jorge

    2006-01-01

    The directed radiotherapy of the solid tumors with fragments recombinants of radiolabelled antibodies is a topic of current investigation, so much at preclinical level as clinical. This work describes the preclinical characterization of a new fragment type diabody of the AcMo ior CEA1 that has been labelled with 131 I for their use in the diagnosis and the therapy of CEA positive tumors. The radiolabelling methodology used allows the incorporation of more than 90% of the radio iodine to the molecule without committing the capacity of recognition of its antigen significantly. The combination of the favourable properties pharmacy kinetic and high selective accumulation in the tumor, they make of the diabody anti CEA an appropriate candidate for the radioimmunodiagnosis and the radioimmunotherapy of tumors that expresses CEA (Author)

  3. Postharvest quality of essential oil treated roses

    Directory of Open Access Journals (Sweden)

    Guilherme Mariano Manfredini

    2017-07-01

    Full Text Available The loss of commercial quality during storage and transportation of roses is one of the factors that reflect on production costs, leading producers to preventively apply harmful chemicals, mainly to hamper Botrytis cinerea development and reduce further losses. An alternative to increase flower longevity without contaminating the environment with harmful chemicals is the use of natural products, such as essential oils, which have fungistatic and insecticide properties, as well as low toxicity. The objective of this study was to evaluate the effect of essential oils on the vase life of Rosa cv. Avalanche: 12 treatments were tested, resulting from the combination of 5 types of essential oils plus the control in two cold storage periods (2 to 6 days at 1 °C, 90-95% RH. The essential oils tested were eucalyptus, cinnamon, lemongrass and peppermint (1%, clove (0.1%, plus a control with distilled water. Application was made by spraying the flower buds. After storage at low temperatures, the flower stems were kept in a room (16 °C, 70% RH during 10 days for evaluation. Flower stems stored for 2 days in a cold chamber showed better means for darkening, turgor and bent neck, as well as a lower weight loss by the stems. The application of lemongrass essential oil at 1% caused burns on the petals, compromising quality and pot life. The essential oils of peppermint and eucalyptus allowed flower quality maintenance until the 10th day of evaluation. It is possible to conclude that post-harvest spraying with peppermint or eucalyptus essential oil at 1%, combined with cold storage for 2 days, provided greater longevity and quality for cv. Avalanche roses.

  4. Genetic fingerprinting of mutant rose cultivars

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S; Prasad, K V; Singh, K P; Singh, A.P. [Division of Floriculture and Landscaping, Indian Agricultural Research Institute, Pusa, New Delhi (India)], E-mail: kvprasad66@gmail.com

    2008-07-01

    Six rose mutants evolved at the Indian Agricultural Research Institute, New Delhi from four parent cultivars were characterized based on RAPD markers. Contrary to the earlier findings our effort has conclusively proven that the RAPD markers are indeed robust tools to discern the mutants from their parents. Among 40 primers screened, 7 primers produced inconsistent banding pattern. The number of polymorphic bands varied between 4 (OPA 14) and 10 (OPA1) with an average of 6.5 bands per primer. The percentage polymorphism ranged from 62.5 (OPM 9) to 100 percent (OPA 1). Most of the primers produced monomorphic bands between parent and mutant rose cultivars. When primer OPA 2 was used a specific band of 2.5 kb was noticed in mutant cv. Pusa Urmil and cv. Pusa Abhishek but was absent in parent cv. Jantar Mantar. A polymorphic band of 750 bp was noticed in the parent Kiss of Fire and helped in differentiating the parent from its mutant when amplified with OPK 3. Primer OPS 16 produced discriminatory band of 800 bp in mutant cv. Pink Sport of Montezuma while it was absent in its parent cv. Montezuma. Another specific band of 650 bp was present in parent cv. Montezuma and absent in its mutant cv. Pink Sport of Montezuma signifying the uniqueness of the mutant. Primer OPM 5 brought out distinct polymorphism among the parent Jantar Mantar and its three mutants with absence of a specific band of 1.5 kb in the parent. The four parents and 6 mutants were divided into four distinct groups in the Dendogram constructed by UPGMA method. The most genetically similar cultivar among the 10 cultivars analyzed are Montezuma and its pink sport of Montezuma whereas Abhisarika a mutant of cv. Kiss of Fire was distinctly different and formed a separate cluster. (author)

  5. The CEA at the heart of great new challenges - Annual report 2015. The CEA - Financial report 2015

    International Nuclear Information System (INIS)

    2016-06-01

    The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas: defence and security, nuclear energy (fission and fusion), technological research for industry, fundamental research in the physical sciences and life sciences. Drawing on its widely acknowledged expertise, the CEA actively participates in collaborative projects with a large number of academic and industrial partners. The CEA is established in nine centers spread throughout France. It works in partnership with many other research bodies, local authorities and universities. Within this context, the CEA is a stakeholder in a series of national alliances set up to coordinate French research in energy (ANCRE), life sciences and health (AVIESAN), digital science and technology (ALLISTENE), environmental sciences (AllEnvi) and human and social sciences (ATHENA). The CEA in figures (2015): 9 research centres; 15958 technicians, engineers, researchers and staff; 51 joint research units (UMR); 53 framework agreements with universities and schools; 753 priority patents filed in 2015; 27 Equipex (facilities of excellence); 33 Labex (Laboratories of excellence); 3 Idex (Initiatives of excellence); 187 start-ups since 1972 in the innovative technologies sector; 4,1 billion euros budget; 438 ongoing European projects in 2015. This document is the activity report of CEA over the year 2015 (Defence, energy, technologies, fundamental research..). It is followed by a Management and a financial report (annual Financial Statements)

  6. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer.

    Science.gov (United States)

    Grunnet, M; Sorensen, J B

    2012-05-01

    The use of CEA as a prognostic and predictive marker in patients with lung cancer is widely debated. The aim of this review was to evaluate the results from studies made on this subject. Using the search words "CEA", "tumor markers in lung cancer", "prognostic significance", "diagnostic significance" and "predictive significance", a search was carried out on PubMed. Exclusion criteria was articles never published in English, articles before 1981 and articles evaluating tumor markers in lung cancer not involving CEA. Initially 217 articles were found, and 34 were left after selecting those relevant for the present study. Four of these included both Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC) patients, and 31 dealt solely with NSCLC patients. Regarding SCLC no studies showed that serum level of CEA was a prognostic marker for overall survival (OS). The use of CEA serum level as a prognostic marker in NSCLC was investigated in 23 studies and the use of CEA plasma level in two. In 18 (17 serum, 1 plasma) of these studies CEA was found to be a useful prognostic marker for either OS, recurrence after surgery or/and progression free survival (PFS) in NSCLC patients. Interestingly, an overweight of low stage (stage I-II) disease and adenocarcinoma (AC) patients were observed in this group. The remaining 7 studies (6 serum, 1 plasma) contained an overweight of patients with squamous carcinoma (SQ). One study found evidence for that a tumor marker index (TMI), based on preoperative CEA and CYFRA21-1 serum levels, is useful as a prognostic marker for OS in NSCLC. Six studies evaluated the use of CEA as a predictive marker for risk of recurrence and risk of death in NSCLC patients. Four of these studies found, that CEA was useful as a predictive marker for risk of recurrence and risk of death measured over time. No studies found CEA levels useful as a diagnostic marker for lung cancer. With regard to NSCLC the level of CEA measured in tumor tissue in

  7. Vigour evaluation for genetics and breeding in rose

    NARCIS (Netherlands)

    Yan, Z.; Dolstra, O.; Hendriks, T.; Prins, T.W.; Stam, P.; Visser, P.B.

    2005-01-01

    Breeding of cut and pot rose cultivars for efficient production under low-energy conditions in greenhouses will be facilitated by understanding the inheritance of vigour. To get insight into the genetic variation of vigour-related traits, a diploid rose population was employed for an evaluation

  8. Femi, Brake Mechanic: Kinesthetic Learning and Mike Rose's "Remedial" Education

    Science.gov (United States)

    Martin, Tom

    2012-01-01

    Mike Rose, author of "The Mind at Work," extols both the wholesome, pragmatic qualities of handcraft and the implicit intellectual skills required of its practitioners. His recent article, "Rethinking Remedial Education and the Academic-Vocational Divide," is titled with a call to action; in these few words alone, Rose problematizes the polar…

  9. Molecular and biochemical studies of fragrance biosynthesis in rose

    NARCIS (Netherlands)

    Sun, P.

    2017-01-01

    Roses are one of the most popular ornamental plants, whose floral volatiles are not only involved in environmental interactions but also widely used by industries. The biosynthesis of many of these volatiles in roses is not well understood. This thesis describes alternative pathways for the

  10. Characterizing and identifying black spot resistance genes in polyploid roses

    Science.gov (United States)

    The ornamental quality of outdoor grown roses (Rosa hybrida) is under constant threat from foliar diseases, such as black spot caused by Diplocarpon rosae. Fungicides are primarily used to manage black spot; however, there is a high consumer demand for disease resistant roses which eliminate the nee...

  11. Dissecting black spot resistance in polyploid hybrid roses

    Science.gov (United States)

    Devastating foliar diseases, such as black spot caused by Diplocarpon rosae, pose constant threats to the ornamental quality of outdoor grown roses. Black spot is primarily managed though the use of fungicides, however, there is a high demand for resistant roses which require low chemical inputs. To...

  12. Effects of irradiation on freshkeeping of rose cut-flower

    International Nuclear Information System (INIS)

    Ding Zengcheng; Li Chuntao; Tang Fei; Xu Hongqing; Shi Dan

    2003-01-01

    Effects of irradiation treatment on the freshkeeping of rose cut-flower were studied. The result showed that respiratory rate, Pro, MDA and colour of rose changed after irradiated with 0, 50, 100, 200 and 300 Gy treatments, and the florescence period was prolonged with 200 and 300 Gy treatments

  13. Genetic diversity and genetic similarities between Iranian rose species

    NARCIS (Netherlands)

    Samiei, L.; Naderi, R.; Khalighi, A.; Shahnejat-Bushehri, A.A.; Mozaffarian, V.; Esselink, G.D.; Kazempour Osaloo, S.; Smulders, M.J.M.

    2010-01-01

    Wild rose species were collected from different regions of Iran for a rose breeding programme. They included accessions from Rosa persica, R. foetida, R. pimpinellifolia, R. hemisphaerica, R. canina, R. iberica, R. damascena, R. beggeriana, and R. orientalis. Ten microsatellite (simple sequence

  14. Those who pull a rose of sharon off

    International Nuclear Information System (INIS)

    Lee, Byeong Yeong

    2011-06-01

    The contents of this book are going over the U. S. policy on nuclear issue, to bloom a rose of sharon, people who pull a rose of sharon off discharge out of appointment and participation into administration and trial on election law, over the farm hardship period, the story about development of nuclear energy. The report and the contract and the related articles.

  15. Alternaria toxin-induced resistance in rose plants against rose aphid (Macrosiphum rosivorum): effect of tenuazonic acid.

    Science.gov (United States)

    Yang, Fa-zhong; Yang, Bin; Li, Bei-bei; Xiao, Chun

    2015-04-01

    Many different types of toxins are produced by the fungus, Alternaria alternata (Fr.) Keissler. Little is known, however, regarding the influence of these toxins on insects. In this study, we investigated the toxin-induced inhibitory effects of the toxin produced by A. alternata on the rose aphid, Macrosiphum rosivorum, when the toxin was applied to leaves of the rose, Rosa chinensis. The results demonstrated that the purified crude toxin was non-harmful to rose plants and rose aphids, but had an intensive inhibitory effect on the multiplication of aphids. The inhibitory index against rose aphids reached 87.99% when rose plants were sprayed with the toxin solution at a low concentration. Further results from bioassays with aphids and high performance liquid chromatography (HPLC) analyses demonstrated that tenuazonic acid (TeA) was one of the most important resistance-related active components in the crude toxin. The content of TeA was 0.1199% in the crude toxin under the HPLC method. Similar to the crude toxin, the inhibitory index of pure TeA reached 83.60% 15 d after the rose plants were sprayed with pure TeA solution at the lower concentration of 0.060 μg/ml, while the contents of residual TeA on the surface and in the inner portion of the rose plants were only 0.04 and 0.00 ng/g fresh weight of TeA-treated rose twigs, respectively, 7 d after the treatment. Our results show that TeA, an active component in the A. alternata toxin, can induce the indirect plant-mediated responses in rose plants to intensively enhance the plant's resistances against rose aphids, and the results are very helpful to understand the plant-mediated interaction between fungi and insects on their shared host plants.

  16. Healing incisional surgical wounds using Rose Hip oil in rats

    Directory of Open Access Journals (Sweden)

    Lainy Carollyne da Costa Cavalcante

    2017-03-01

    Full Text Available Purpose: To evaluate incisional surgical wound healing in rats by using Rose Hip (Rosa rubiginosa L. oil. Methods: Twenty-one days after the oophorectomy procedure, twenty-seven female, adult, Wistar rats were distributed into three groups: Control group (wound treatment with distilled water; Collagenase group (treatment with collagenase ointment; and Rose Hip group (wound treatment with Rose Hip oil. Each group was distributed according to the date of euthanasia: 7, 14 and 21 days. The wound was evaluated considering the macroscopic and microscopic parameters. Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Rose Hip oil in comparison to the control and collagenase, especially after the 14th day. Morphometric data confirmed the structural findings. Conclusion: There was significant effect in topical application of Rose Hip oil on incisional surgical wound healing.

  17. Rose, a rotating system for 4D emittance measurements

    Energy Technology Data Exchange (ETDEWEB)

    Maier, Michael; Groening, Lars; Xiao, Chen; Mickat, Sascha; Du, Xiaonan; Gerhard, Peter; Vormann, Hartmut [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany)

    2016-07-01

    A ROtating System for Emittance measurements ROSE, to measure the full 4 dimensional transverse beam matrix of a heavy ion beam has been developed and commissioned. Different heavy ion beams behind the HLI at GSI have been used in two commissioning beam times. All technical aspects of Rose have been tested, Rose has been benchmarked against existing emittance scanners for horizontal and vertical projections and the method, hard- and software to measure the 4D beam matrix has been upgraded, refined and successfully commissioned. The inter plane correlations of the HLI beam have been measured, yet as no significant initial correlations were found to be present, controlled coupling of the beam by using a skew triplet has been applied and confirmed with Rose. The next step is to use ROSE to measure and remove the known inter plane correlations of a Uranium beam before SIS18 injection.

  18. Les agriculteurs s'adaptent aux changements climatiques en Tunisie ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 août 2011 ... Les eaux grises et la culture en serre augmentent la production alimentaire en Tunisie ... Des chercheurs insistent sur l'importance de favoriser la résilience aux ... Vulnérabilité et adaptation aux changements climatiques des ...

  19. Demodicidosis en pacientes con rosácea

    Directory of Open Access Journals (Sweden)

    Edhizon Trejo Mucha

    2007-01-01

    Full Text Available Objetivo: Determinar la frecuencia de demodicidosis y sus características clínicas en pacientes con rosácea. Materiales y métodos: Estudio de casos y controles en 42 pacientes con rosácea y 42 controles para describir la presencia y densidad de D. folliculorum. El estudio se realizó en el Hospital Nacional Cayetano Heredia entre marzo y setiembre del 2004, utilizándose la técnica de Tello. Resultados: Demodex folliculorum fue encontrado en los 42 pacientes con rosácea (100% y en 13 (31,0% del grupo control, (p= 0,000. La exposición a gatos, la crianza de roedores y cerdos, la seborrea y el uso de corticoides tópicos fueron mas frecuentes en los pacientes con rosácea. Conclusiones: La presencia de Demodex folliculorum fue más frecuente en los pacientes con rosácea. (Rev Med Hered 2007;18:15-21.

  20. Fusion technology. Annual report of the. Association Cea/EURATOM

    International Nuclear Information System (INIS)

    Magaud, P.; Le Vagueres, F.

    1996-01-01

    In 1996, the French EURATOM-CEA Association made significant contributions to the European technology programme. This work is compiled in this report as follows: the ITER CEA activities and related developments are described in the first section; blankets and material developments for DEMO, long term safety studies are summarised in the second part; the Underlying Technology activities are compiled in the third part of this report. In each section, the tasks are sorted out to respect the European presentation. For an easy reading, appendix 4 gives the list of tasks in alphabetical order with a page reference list. The CEA is in charge of the French Technology programme. Three specific organizational directions of the CEA, located on four sites (see appendix 5) are involves in this programme: Advanced Technologies Direction (DTA), for Material task; Nuclear Reactors Direction (DRN), for Blanket design, Neutronic problems, Safety tasks; Physical Sciences Direction (DSM) uses the competence of the Tore Supra team in the Magnet design and plasma Facing Component field. The CEA programme is completed by collaborations with Technicatome, COMEX-Nucleaire and Ecole Polytechnique. The breakdown of the programme by Directions is presented in figure 1. The allocation of tasks is given in appendix 2 and in appendix 3, the related publications. (author)

  1. Introduction to the CEA family: structure, function and secretion.

    Science.gov (United States)

    Von Kleist, S

    1992-01-01

    Due to the phenomenal progress in the field of tumor immunology that took place during the last twenty years, we dispose today of highly specific and sensitive techniques and reagents like monoclonal antibodies (MAbs). In this context the discovery in human carcinomas of tumor-associated antigens, such as CEA, was of primary importance, especially since the latter was found to have clinical relevance as a tumor marker. Based on animal models, a new in vivo technology for the detection of tumors and metastases was developed in recent years, that uses anti-CEA MAbs, or fragments of them, coupled to radio-isotopes. This technique, called radio-immunodetection (RAID), also paved the way for immunotherapeutic procedures, where again CEA served as the target-antigen. This new technique holds great promise, provided the epitope-specificity of the MAbs is well-controlled: it has been shown that CEA belongs to a large gene-family of at least 22 members, which can be subdivided into two subgroups (i.e., the CEA- and the PSG-subgroup) and which in turn belongs to the immunoglobulin-supergene family. Great structural similarities render the distinction of the various cross-reactive molecules by immunological means rather difficult.

  2. Dieback of rose caused by Acremonium sclerotigenum as a new causal agent of rose dieback in Iran

    International Nuclear Information System (INIS)

    Mirtalebi, M.; Banihashemi, Z.; Sabahi, F.; Mafakheri, H.

    2016-01-01

    Severe dieback of rose has been recently observed in several rose greenhouses in Fars province of Iran. During 2014 and 2015, stems of rose plants showing yellow to brown discoloration and dieback were collected from rose greenhouses. Coniothyrium fuckelii, Botrytis cinerea and Acremonium were subsequently isolated from the margin between healthy and symptomatic tissue. B. cinerea and C. fuckelii isolates were similar to those previously reported for dieback of rose worldwide. Morphological and cultural characters along with molecular analysis based on partial sequences of the internal transcribed spacer (ITS) region of the ribosomal RNA genome allowed confirming the affiliation of the Acremonium isolates, corresponding to A. sclerotigenum as a new causal agent of rose dieback. To determine its pathogenicity on rose, Koch's postulates were fulfilled by stem inoculation of nine rose cultivars under greenhouse conditions. While A. sclerotigenum is considered as a soil-born pathogen, and produces sclerotia that are resistant to adverse conditions enables the fungus to survive extended period in soil, propagule trapping in our study revealed that conidia can become airborn, imply that an aerial phase, forms an important component of the disease cycle.

  3. Volatile constituents of essential oil and rose water of damask rose (Rosa damascena Mill.) cultivars from North Indian hills.

    Science.gov (United States)

    Verma, Ram Swaroop; Padalia, Rajendra Chandra; Chauhan, Amit; Singh, Anand; Yadav, Ajai Kumar

    2011-10-01

    Rosa damascena Mill. is an important aromatic plant for commercial production of rose oil, water, concrete and absolute. The rose water and rose oil produced under the mountainous conditions of Uttarakhand were investigated for their chemical composition. The major components of rose water volatiles obtained from the bud, half bloom and full bloom stages of cultivar 'Ranisahiba' were phenyl ethyl alcohol (66.2-79.0%), geraniol (3.3-6.6%) and citronellol (1.8-5.5%). The rose water volatiles of cultivar 'Noorjahan' and 'Kannouj' also possessed phenyl ethyl alcohol (80.7% and 76.7%, respectively) as a major component at full bloom stage. The essential oil of cultivar 'Noorjahan' obtained from two different growing sites was also compared. The major components of these oils were citronellol (15.9-35.3%), geraniol (8.3-30.2%), nerol (4.0-9.6%), nonadecane (4.5-16.0%), heneicosane (2.6-7.9%) and linalool (0.7-2.8%). This study clearly showed that the flower ontogeny and growing site affect the composition of rose volatiles. The rose oil produced in this region was comparable with ISO standards. Thus, it was concluded that the climatic conditions of Uttarakhand are suitable for the production of rose oil of international standards.

  4. Rose parental characterization and population development for the identification of novel rose black spot resistance genes [abstract

    Science.gov (United States)

    Rose black spot disease, caused by the pathogen Diplocarpon rosae Wolf, is one of the most widespread and serious diseases of outdoor-grown roses worldwide. Defoliation caused by the disease compromises ornamental value, and repeated defoliation events weakens plants and can lead to plant death. Bot...

  5. Dieback of rose caused by Acremonium sclerotigenum as a new causal agent of rose dieback in Iran

    Energy Technology Data Exchange (ETDEWEB)

    Mirtalebi, M.; Banihashemi, Z.; Sabahi, F.; Mafakheri, H.

    2016-07-01

    Severe dieback of rose has been recently observed in several rose greenhouses in Fars province of Iran. During 2014 and 2015, stems of rose plants showing yellow to brown discoloration and dieback were collected from rose greenhouses. Coniothyrium fuckelii, Botrytis cinerea and Acremonium were subsequently isolated from the margin between healthy and symptomatic tissue. B. cinerea and C. fuckelii isolates were similar to those previously reported for dieback of rose worldwide. Morphological and cultural characters along with molecular analysis based on partial sequences of the internal transcribed spacer (ITS) region of the ribosomal RNA genome allowed confirming the affiliation of the Acremonium isolates, corresponding to A. sclerotigenum as a new causal agent of rose dieback. To determine its pathogenicity on rose, Koch's postulates were fulfilled by stem inoculation of nine rose cultivars under greenhouse conditions. While A. sclerotigenum is considered as a soil-born pathogen, and produces sclerotia that are resistant to adverse conditions enables the fungus to survive extended period in soil, propagule trapping in our study revealed that conidia can become airborn, imply that an aerial phase, forms an important component of the disease cycle.

  6. Determination of volatile compounds of the first rose oil and the first ...

    African Journals Online (AJOL)

    Background: Rose water and rose oil are used in the perfume, cosmetic, pharmaceutical and food industries. The determination of volatile compounds in rose oil and rose water obtained from oil-bearing rose is highly important in terms of availability in the industry and in human health. Materials and Methods: Twenty four ...

  7. 2nd CEAS Specialist Conference on Guidance, Navigation and Control

    CERN Document Server

    Mulder, Bob; Choukroun, Daniel; Kampen, Erik-Jan; Visser, Coen; Looye, Gertjan

    2013-01-01

    Following the successful 1st CEAS (Council of European Aerospace Societies) Specialist Conference on Guidance, Navigation and Control (CEAS EuroGNC) held in Munich, Germany in 2011, Delft University of Technology happily accepted the invitation of organizing the 2nd  CEAS EuroGNC in Delft, The Netherlands in 2013. The goal of the conference is to promote new advances in aerospace GNC theory and technologies for enhancing safety, survivability, efficiency, performance, autonomy and intelligence of aerospace systems using on-board sensing, computing and systems. A great push for new developments in GNC are the ever higher safety and sustainability requirements in aviation. Impressive progress was made in new research fields such as sensor and actuator fault detection and diagnosis, reconfigurable and fault tolerant flight control, online safe flight envelop prediction and protection, online global aerodynamic model identification, online global optimization and flight upset recovery. All of these challenges de...

  8. Thermodynamique des moteurs thermiques aux structures dissipatives

    CERN Document Server

    Prigogine, Ilya

    1999-01-01

    Ce livre constitue à la fois une présentation complète de la thermodynamique et une introduction scientifique à l'œuvre de Prigogine. Les auteurs innovent en montrant comment la thermodynamique du non-équilibre est un prolongement naturel de la thermodynamique de l'équilibre. Elle constitue ainsi la science des processus irréversibles - " la flèche du temps " - dont les structures dissipatives sont les témoignages les plus éclatants. Les développements historiques en font, non seulement un texte de référence, mais aussi un livre de culture. Les nombreux exemples et exercices, comme les programmes informatiques et les références aux sites Internet en font un outil de travail irremplaçable.

  9. The opening of the CEA to the general public

    International Nuclear Information System (INIS)

    Deloche, Robert

    1999-01-01

    Full text: The relationships between science and society have evolved considerably over the past years, just like the perception of the nuclear industry in the French public opinion. Recent psychosociological surveys show that only half of the French population is familiar with the CEA and that the public would like to obtain new elements of judgment in order to be able to develop a direct appreciation of the activities of a research organization such as the Atomic Energy Commission. It is essential to meet the public's expectations, to keep it properly informed of the CEA's research activities, and to help it understand the relevance of the results obtained and the solutions offered to decision-makers, i.e. industrialists and public authorities. One way to answer the public opinion's questions and to meet its expectations is to allow a rowing number of visitors to see who we are, what we study in our laboratories, and how we work to contribute to scientific progress and to the diffusion of technology, in a manner that is useful to society as a whole. This describes the spirit and the objective that governed the very idea and elaboration of the program entitled 'Opening of the CEA to the general public'. This operation consists not only in having communication specialists guide visitors throughout the facilities and equipment of the CEA, but also in encouraging researchers and groups of visitors to meet in the laboratories. A 'CEA - communication' network is under construction. It already has nearly 600 members. Communication is considered to be a real calling that falls within the scope of the CEA's strategy, and the work accomplished in this respect is recognized to the same extent as research. To this end, a charter for the CEA - communication network will be signed by every contributor and manager. A training scheme focused on public speaking and scientific vulgarization was initiated. 50 members of the network have already been trained, and 250 will be in 1999

  10. The CEA-industrie Group. Report for 1986

    International Nuclear Information System (INIS)

    1987-01-01

    From the end of 1983, the whole affiliates and participations of CEA are hept by CEA-industry. The group activity is principally in the nuclear field. Cogema and the whole fuel cycle, construction, maintenance, improvement of nuclear power plants, research reactors and naval propulsion boilers and the sector Power plants and nuclear services (Framatome, Technicatome, Intercontrole, Stmi, principally). A non-nuclear sector comes from new techniques or activities developed for the nuclear needs: computer science (CISI), biomedical field (ORIS-industrie), different activities such as ultrafiltration or robotics-productics [fr

  11. CEA 2011, a look back at a year of research

    International Nuclear Information System (INIS)

    2011-01-01

    For this year 2011, marked by the Fukushima accident, the goal is improved safety. This is a key issue being addressed by CEA, while at the same time boosting its R and D on low-carbon energies, defense and security, Health technologies, information technologies and very large research Infrastructures. With more than 650 priority patents filed in 2011, CEA maintains its position as the leading French research organization. CEA stands in 4. place among the European research organizations, in terms of the number of projects (535, including 70 that it coordinates) and financing obtained (nearly euros 55 M) under the European Commission's FP7 framework programme. CEA's civil programs are 30% funded from external revenues (partner companies, national incentive funds, local authorities and European Union), 49% from the Government and, finally, 21% from two funds dedicated to clean-up of civil and defense facilities. Of the euros 1, 391 M devoted to low-carbon energies, research into the new energy technologies and nuclear systems of the future each received a budget of euros 151 M in 2011. CEA plays a key role in the European Energy Research Alliance, as a founding member, a member of the executive committee and a member of the secretariat. It is France's representative. EERA has launched 13 joint programs, including 6 in 2011. It pools the research efforts of more than 150 institutes and universities, with more than 2, 000 staff employed full-time. CEA is present in 8 programs, with 100 full-time staff, in other words 5% of the total partner commitment. This special issue of 'Defis du CEA' journal deals with the main results of the researches carried out in 2011 at the CEA. Contents: 1 - Facts and figures 2011: Intellectual Property, European Financing, Budget, Nuclear Safety, European Research Programs, International Relations, International Collaboration, Spin-off, Scientific Excellence, Training; 2 - Low-carbon energies: Biofuels, Solar Photovoltaic, Nuclear, Energy

  12. CEA 2011, a look back at a year of research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    For this year 2011, marked by the Fukushima accident, the goal is improved safety. This is a key issue being addressed by CEA, while at the same time boosting its R and D on low-carbon energies, defense and security, Health technologies, information technologies and very large research Infrastructures. With more than 650 priority patents filed in 2011, CEA maintains its position as the leading French research organization. CEA stands in 4. place among the European research organizations, in terms of the number of projects (535, including 70 that it coordinates) and financing obtained (nearly euros 55 M) under the European Commission's FP7 framework programme. CEA's civil programs are 30% funded from external revenues (partner companies, national incentive funds, local authorities and European Union), 49% from the Government and, finally, 21% from two funds dedicated to clean-up of civil and defense facilities. Of the euros 1, 391 M devoted to low-carbon energies, research into the new energy technologies and nuclear systems of the future each received a budget of euros 151 M in 2011. CEA plays a key role in the European Energy Research Alliance, as a founding member, a member of the executive committee and a member of the secretariat. It is France's representative. EERA has launched 13 joint programs, including 6 in 2011. It pools the research efforts of more than 150 institutes and universities, with more than 2, 000 staff employed full-time. CEA is present in 8 programs, with 100 full-time staff, in other words 5% of the total partner commitment. This special issue of 'Defis du CEA' journal deals with the main results of the researches carried out in 2011 at the CEA. Contents: 1 - Facts and figures 2011: Intellectual Property, European Financing, Budget, Nuclear Safety, European Research Programs, International Relations, International Collaboration, Spin-off, Scientific Excellence, Training; 2 - Low-carbon energies: Biofuels, Solar

  13. Cleansing and dismantling of CEA-Saclay nuclear licensed facilities

    International Nuclear Information System (INIS)

    Jeanjacques, Michel; Delaire, Isabelle; Glevarec, Rebecca; Mandard, Lionel; Martin, Jean-Louis; Serrano, Roger

    2013-01-01

    This summary presents the cleansing and dismantling operations currently realized on the CEA center of Saclay (CEA-Saclay). It was initiated at the beginning of the 2000 years a cleansing and dismantling program of the old Nuclear Licensed Facilities (NLF). Currently this program relates the dismantling operations to the Hot Laboratories (Laboratoires de Haute Activite: LHA) and the old workshops of the Liquid Waste Treatment Plant (Station des Effluents Liquides: STEL), the dismantling preparation of Ulysse reactor and the dismantling studies to the Solid Waste Management Plant (SWMP; Zone de Gestion des Dechets Solides) and the Osiris reactor. (authors)

  14. Gamma ray induced somatic mutations in rose

    International Nuclear Information System (INIS)

    Datta, S.K.

    1989-01-01

    Budwood of 32 rose cultivars (Rosa spp.) was exposed to 3-4 krad of gamma rays and eyes were grafted on Rosa indica var. odorata root stock. Radiosensitivity with respect to sprouting, survival and plant height, and mutation frequency varied with the cultivar and dose of gamma rays. Somatic mutations in flower colour/shape were detected as chimera in 21 cultivars. The size of the mutant sector varied from a narrow streak on a petal to a whole flower and from a portion of a branch to an entire branch. 14 mutants were detected in M 1 V 1 , four in M 1 V 2 and three in M 1 V 3 . Maximum number of mutations was detected following 3 krad treatment. Eyes from mutant branches were grafted again on root stock and non-chimeric mutants were aimed at by vegetative propagation. Mutants from 11 cultivars only could be isolated in pure form. Isolation of non-chimeric mutants sometimes is difficult due to weak growth of a mutant branch. In such a case, all normal looking branches are removed to force a better growth of the mutant branch. It is advisable to maintain irradiated plants at least for four years with drastic pruning in each year. Nine mutants viz. 'Sharada', 'Sukumari', 'Tangerine Contempo', 'Yellow Contempo', 'Pink Contempo', 'Striped Contempo', 'Twinkle', 'Curio' and 'Light Pink Prize' have already been released as new cultivars for commercialization [ref. MBNL No. 23 and 31] and others are being multiplied and assessed. The mutation spectrum appears to be wider for the cultivars 'Contempo' and 'Imperator'. Pigment composition of the original variety is relevant for the kind of flower colour mutations that can be induced

  15. PLANT VOLATILES. Biosynthesis of monoterpene scent compounds in roses.

    Science.gov (United States)

    Magnard, Jean-Louis; Roccia, Aymeric; Caissard, Jean-Claude; Vergne, Philippe; Sun, Pulu; Hecquet, Romain; Dubois, Annick; Hibrand-Saint Oyant, Laurence; Jullien, Frédéric; Nicolè, Florence; Raymond, Olivier; Huguet, Stéphanie; Baltenweck, Raymonde; Meyer, Sophie; Claudel, Patricia; Jeauffre, Julien; Rohmer, Michel; Foucher, Fabrice; Hugueney, Philippe; Bendahmane, Mohammed; Baudino, Sylvie

    2015-07-03

    The scent of roses (Rosa x hybrida) is composed of hundreds of volatile molecules. Monoterpenes represent up to 70% percent of the scent content in some cultivars, such as the Papa Meilland rose. Monoterpene biosynthesis in plants relies on plastid-localized terpene synthases. Combining transcriptomic and genetic approaches, we show that the Nudix hydrolase RhNUDX1, localized in the cytoplasm, is part of a pathway for the biosynthesis of free monoterpene alcohols that contribute to fragrance in roses. The RhNUDX1 protein shows geranyl diphosphate diphosphohydrolase activity in vitro and supports geraniol biosynthesis in planta. Copyright © 2015, American Association for the Advancement of Science.

  16. Disposal of the radioactive effluents at the 'Commissariat a l'Energie Atomique'. Treatment leading to evacuation into a river; Probleme du rejet des residus radioactifs liquides au CEA. Traitements aboutissant a des rejets en riviere

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel,; Menoux,; Candillon, [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    loaded water, 10) Impot elements other than Sr{sup 90} are also studied. (author) [French] Le probleme du traitement des residus radioactifs liquides au CEA est envisage sous l'angle du rejet ultime en riviere dans des conditions optima permettant de satisfaire aux Normes de la protection. 2) A Saclay, ou l'on ne dispose que d'un etang ou l'eau ne se renouvelle pas, les liquides epures sont envoyes par camion citerne a Fontenay-aux-Roses, ou ils sont deverses provisoirement - dans les egouts - en attendant qu'un point de rejet en Seine ait ete determine. 3) Au Bouchet, les eaux residuaires de l'Usine de traitement de minerais d'urano-thorianite devront etre traitees en deux temps de facon a separer le radium dans une premiere phase, ce qui facilitera l'epuration au cours de la deuxieme phase. 4) En vue des futurs rejets a Marcoule, une etude a ete conduite a Saclay, sur des effluents synthetiques - type Marcoule - ayant pour but de mettre au point des procedes d'elimination selective du Sr d'une part, du Cs d'autre part, par coprecipitation. 5) Dans le cas general du rejet ultime en riviere, les problemes suivants sont successivement envisages: - predilution entre les bassins de stockage des eaux epurees et le fleuve; - mode d'injection dans le fleuve; - dilution dans le fleuve (etude prealable par traceurs); - evolution de l'activite dans les eaux du fleuve (adsorption par les organismes inertes ou vivants, contamination des berges); - incidence sur le choix d'un site; - dilution isotopique. 6) Ce dernier probleme est specialement detaille. 7) La teneur de l'eau en un element donne conditionne la dilution isotopique de son isotope radioactif. L'analyse decelant une carence, il est possible d'y suppleer par des rejets d'isotope stable. 8) Cette methode conduit en certains cas a des analyses delicates (en particulier dans le cas du {sup 90}Sr), la teneur en isotope stable necessaire a une forte dilution isotopique restant faible (ce qui est d'ailleurs un avantage). 9

  17. Criticality accident studies and methodology implemented at the CEA

    International Nuclear Information System (INIS)

    Barbry, Francis; Fouillaud, Patrick; Reverdy, Ludovic; Mijuin, Dominique

    2003-01-01

    Based on the studies and results of experimental programs performed since 1967 in the CRAC, then SILENE facilities, the CEA has devised a methodology for criticality accident studies. This methodology integrates all the main focuses of its approach, from criticality accident phenomenology to emergency planning and response, and thus includes aspects such as criticality alarm detector triggering, airborne releases, and irradiation risk assessment. (author)

  18. Fast reactor physics at CEA: present studies and future prospects

    International Nuclear Information System (INIS)

    Hammer, P.

    1980-09-01

    This paper aims at giving a general survey of the fast reactor core physics and shielding studies wich are in progress at CEA (1979-1983) in order to solve the neutronic problems related to: - core design optimization, - reactor operation and fuel management, - safety, for the development of fast commercial breeders in France after the SUPER-PHENIX 1 construction is achieved

  19. Foreword and introductory comments to CEA annual report 1989

    International Nuclear Information System (INIS)

    1990-01-01

    This article is a foreword to the annual report of the Commisariat a l'Energie Atomique (CEA) and summarises the main achievements of the research teams such as the commissioning of the electron-positron collision ring (LEP), the fuel reprocessing plant at The Hague, the PROTEINE 2000 programme, the laser enrichment programme and advances in microelectronics. (author)

  20. Multiple myeloma presenting as CEA-producing rectal cancer.

    Science.gov (United States)

    Talamo, Giampaolo; Barochia, Amitkumar; Zangari, Maurizio; Loughran, Thomas P

    2010-03-31

    We report the case of a 57-year-old patient with multiple myeloma, characterized by extramedullary involvement of the rectum at presentation. Malignant plasma cells were found to produce carcinoembryonic antigen (CEA), a tumor antigen more commonly associated with rectal adenocarcinomas.

  1. Multiple myeloma presenting as CEA-producing rectal cancer

    Directory of Open Access Journals (Sweden)

    Giampaolo Talamo

    2010-03-01

    Full Text Available We report the case of a 57-year old patient with multiple myeloma, characterized by extramedullary involvement of the rectum at presentation. Malignant plasma cells were found to produce carcinoembryonic antigen (CEA, a tumor antigen more commonly associated with rectal adenocarcinomas.

  2. How Packaging Fleet Renewal Fits French CEA Programs

    International Nuclear Information System (INIS)

    Dumesnil, J.; Malvache, P.; Hugon, F.C.; Sollacaro, M.

    2006-01-01

    CEA's (French Atomic Energy Agency) packaging fleet is dedicated to transportation of test irradiated fuels, of research reactors fuels, of navy propulsion fuels, and of waste coming from and to nuclear plants or facilities. This fleet encompasses more than 30 types of casks ranging from 5 to 30 tons, with either recent designs or other dating back to the seventies. A study has been launched in order to perform a global analysis of the life expectancy of the existing CEA and COGEMA Logistics cask fleets with respect to a 2015 target, in order to anticipate its renewal, while limiting the number of type of cask. Key elements like periodical evolutions of design and transport regulations, lessons learnt of existing casks (design, approval and extensions, operational feedback, maintenance and dismantling) are taken into account in order to ensure compliance and availability of the fleet. Moreover, from design to cask delivery, including regulatory tests, safety analysis report/ CoC, and manufacturing, 3 to 5 years is needed. Therefore cask development should be taken into account earlier of invest and research's programs. The paper will address the current life expectancy study of CEA and COGEMA Logistics packaging fleet, based on lessons learnt and regulation evolution and on general R and D plans by user facilities. It will show how a comprehensive optimized fleet is made available to CEA and other customers. Such a fleet combines optimized investment and uses, thus entailing synergies for well-mastered costs of transports. (authors)

  3. Carcinoembryonic Antigen (CEA) in colorectal cancer follow-up

    NARCIS (Netherlands)

    Verberne, Charlotte

    2016-01-01

    Colorectal cancer follow-up aims to detect recurrent disease as soon as possible, since earlier detection of recurrent disease is associated with greater chances for cure. A part of follow-up is the measurement of Carcinoembryonic Antigen (CEA) in the blood of the patient. This tumor marker is

  4. Cancer imaging with CEA antibodies: historical and current perspectives.

    Science.gov (United States)

    Goldenberg, D M

    1992-01-01

    This article reviews the history and status of cancer imaging with radiolabeled antibodies against carcinoembryonic antigen (CEA). Although CEA and many other cancer-associated antigens are not distinct for neoplasia, the quantitative increase of these markers in malignant tissues provides a sufficient differential for selective antibody targeting. Animal studies with xenografted human tumors provided the first evidence of the prospects of this technology, followed by initial clinical success with purified goat whole IgG antibodies to CEA, labeled with 131I and with the use of dual-isotope subtraction methods. Subsequently, improved and earlier imaging could be accomplished with monoclonal antibody fragments, which then would permit the use of shorter-lived radionuclides, such as 111In, 123I, and 99mTc. The preferred use of a monoclonal anti-CEA IgG Fab' fragment, labeled with 99mTc by a recently developed, simple and rapid kit, has enabled the detection of small lesions, including those in the liver, within 4 h of injection. By means of SPECT imaging, a high sensitivity and specificity for RAID could be achieved.

  5. Serum carcinoembryonic antigen (CEA) in chronic renal failure

    International Nuclear Information System (INIS)

    Pyo, H.J.; Kim, S.G.; Shin, Y.T.; Kwon, I.S.; Chung, S.I.; Lee, J.S.; Koh, C.S.

    1980-01-01

    The serum CEA levels were measured by radioimmunoassay technique in 15 patients with chronic renal failure, who were not treated with hemodialysis, in 39 patients under hemodialysis and in 23 patients who received renal transplantation. The results were compared with those in 65 normal adults and the following results were obtained. 1) Serum CEA concentrations in 65 normal adults were in the range of 1.0 to 4.3 ng/ml with a mean value of 1.6+-0.66 ng/ml. 2) Serum CEA concentrations in 15 chronic renal failure patients who were not treated with hemodialysis, were in the range of 0.3 to 8.3 ng/ml with a mean value of 3.6+-2.10 ng/ml which was significantly higher than those of normal controls (P 0.05). 4) In 23 patients who received renal transplantation, serum CEA levels were significantly higher than normal controls (P<0.001), but not significantly different from those of chronic renal failure patients. (author)

  6. Some activities at CEA related to behaviour of core internals

    International Nuclear Information System (INIS)

    Petrequin, P.

    1998-01-01

    Eighteen transparencies where presented, elaborating some activities at CEA related to behaviour of core internals. After some introduction, ten of the transparencies are essentially a copy of the table of contents of the AMES report no. 11 (report no: EUR 17694 EN). The remaining 6 foils concerned themselves with irradiation experiments in test reactors, namely the IDAHO, CASIMIR and ALEXANDRA experiments

  7. Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene

    International Nuclear Information System (INIS)

    Nöckel, Jessica; Engel, Natasja K van den; Winter, Hauke; Hatz, Rudolf A; Zimmermann, Wolfgang; Kammerer, Robert

    2006-01-01

    Gastric carcinoma is one of the most frequent cancers worldwide. Patients with gastric cancer at an advanced disease stage have a poor prognosis, due to the limited efficacy of available therapies. Therefore, the development of new therapies, like immunotherapy for the treatment of gastric cancer is of utmost importance. Since the usability of existing preclinical models for the evaluation of immunotherapies for gastric adenocarcinomas is limited, the goal of the present study was to establish murine in vivo models which allow the stepwise improvement of immunotherapies for gastric cancer. Since no murine gastric adenocarcinoma cell lines are available we established four cell lines (424GC, mGC3, mGC5, mGC8) from spontaneously developing tumors of CEA424/SV40 T antigen (CEA424/Tag) mice and three cell lines derived from double-transgenic offsprings of CEA424/Tag mice mated with human carcinoembryonic antigen (CEA)-transgenic (CEA424/Tag-CEA) mice (mGC2 CEA , mGC4 CEA , mGC11 CEA ). CEA424/Tag is a transgenic C57BL/6 mouse strain harboring the Tag under the control of a -424/-8 bp CEA gene promoter which leads to the development of invasive adenocarcinoma in the glandular stomach. Tumor cell lines established from CEA424/Tag-CEA mice express the well defined tumor antigen CEA under the control of its natural regulatory elements. The epithelial origin of the tumor cells was proven by morphological criteria including the presence of mucin within the cells and the expression of the cell adhesion molecules EpCAM and CEACAM1. All cell lines consistently express the transgenes CEA and/or Tag and MHC class I molecules leading to their susceptibility to lysis by Tag-specific CTL in vitro. Despite the presentation of CTL-epitopes derived from the transgene products the tumor cell lines were tumorigenic when grafted into C57BL/6, CEA424/Tag or CEA424/Tag-CEA-transgenic hosts and no significant differences in tumor take and tumor growth were observed in the different hosts

  8. Luminescence dating at Rose cottage cave: a progress report

    CSIR Research Space (South Africa)

    Woodborne, S

    1997-10-01

    Full Text Available Deal with infrared-stimulated luminescence and thermoluminescence dates from Rose Cottage Cave in South Africa. Discrepancy between luminescence and radiocarbon dates; Concentration of radioactive elements in sediments before and after leaching...

  9. Rose Canyon Sustainable Aquaculture Project, San Diego, CA

    Science.gov (United States)

    Documents related to EPA's preparation of an Environmental Assessment (EA) to analyze the potential impacts related to the issuance of a National Pollutant Discharge Elimination System (NPDES) permit for the Rose Canyon Sustainable Aquaculture Project.

  10. An alternative bifurcation analysis of the Rose-Hindmarsh model

    International Nuclear Information System (INIS)

    Nikolov, Svetoslav

    2005-01-01

    The paper presents an alternative study of the bifurcation behavior of the Rose-Hindmarsh model using Lyapunov-Andronov's theory. This is done on the basis of the obtained analytical formula expressing the first Lyapunov's value (this is not Lyapunov exponent) at the boundary of stability. From the obtained results the following new conclusions are made: Transition to chaos and the occurrence of chaotic oscillations in the Rose-Hindmarsh system take place under hard stability loss

  11. Bekæmpelse af rynket rose II

    DEFF Research Database (Denmark)

    Buttenschøn, Rita M.; Ransijn, Johannes

    2014-01-01

    Rynket rose er en invasiv art, der har spredt sig voldsomt gennem de seneste år – ikke kun i Danmark men i hele Europa. Den er svær at bekæmpe, og derfor har Naturstyrelsen Thy og Thisted Kommune i perioden 2010-2013 gennemført en række kontrollerede forsøg med slåning, græsning og kemisk...... bekæmpelse af rynket rose....

  12. Serum CEA (carcino-embryonic antigen) monitoring after surgery for cancer of the rectum and colon

    International Nuclear Information System (INIS)

    Reginster, J.Y.; Desaive, C.; Collette, J.; Zangerle, P.F.; Denis, D.; Franchimont, P.

    1984-01-01

    Fifty four patients, operated for colorectal cancer have been followed up for 2 to 100 months after surgery by carcino-embryonic antigen (CEA) determinations and classical, clinical, biological, radiological, echographical, isotopical and tomoscanninvestigations. Each new serum sample has been assayed for CEA with previously collected samples within the same patients. This repetition of CEA on the same samples allows to check the good reproducibility of CEA radioimmunoassay (variation coefficient between assay is less than 10%) and to get a complete profile of CEA level evaluation within the same assay. There is a good correlation between clinical evolution and CEA levels. In 42 patients, CEA levels remained or became normal ( 20 ng ml) at the same time or before clinical and/or paraclinical evidences for metastases or local recurrence. These results showed CEA assay in a quantitative parameter to assess the follow-up of colorectal cancer complementary to clinical, biological, radiological, echographical and isotopical criterias [fr

  13. Notre-Dame des Fleurs et Miracle de la rose, de Jean Genet. L’écriture mise au secret

    Directory of Open Access Journals (Sweden)

    Pascaline Hamon

    2011-12-01

    Full Text Available Notre-Dame des Fleurs et Miracle de la Rose sont les deux romans que Jean Genet a composés durant des périodes d’incarcération. La fiction se veut alors non seulement un remède à la solitude carcérale et à la marginalisation de son auteur, mais également un lieu de dévoilement des pratiques d’écriture propres à l’univers carcéral. Le roman tout entier se trouve dès lors habité d’une tension entre la liberté créatrice, qui fait la part belle aux provocations de l’auteur et à l’expression de ses fantasmes et un enfermement contraignant, qui pèse comme une menace sur la possibilité d’écrire.Our Lady of the Flowers and Miracle of the Rose were written during Genet’s time of imprisonment. The fictional narrative operates not only as a remedy to the experience of solitude and marginalization, but also brings the practice of prison writings into focus. The novels are haunted by a tension between a creative freedom which can launch provocations and phantasms, and the constraint of imprisonment, which threatens the very possibility of writing.

  14. Postharvest quality of cut roses following electron-beam irradiation

    International Nuclear Information System (INIS)

    Chang, A.Y.; Gladon, R.J.; Gleason, M.L.; Parker, S.K.; Agnew, N.H.; Olson, D.G.

    1997-01-01

    Cut Rosa x hybrida L. 'Royalty' flowers were used to determine the efficacy of electron-beam irradiation for increasing postharvest quality and decreasing petal infection by Botrytis cinerea Pers. In an experiment for determining the injury threshold, roses received electron-beam irradiation of 0, 0.5, 1, 2, and 4 kGy. Irradiation dosages greater than or equal to 4 kGy caused necrosis on petal tissue and decreased postharvest life at 20 degrees C. In a second experiment to evaluate postharvest quality, roses were irradiated at 0, 0.25, 0.5, 0.75, and 1 kGy. Dosages of 0.25 and 0.5 kGy slowed the rate of flower bud opening for 2 days but did not decrease postharvest quality when compared with nonirradiated roses. Roses that received irradiation dosages of 0.75 and 1 kGy showed unacceptable quality. In a third experiment, roses that had or had not been inoculated with B. cinerea were irradiated at 0, 0.25, 0.5, and 0.75 kGy. Irradiation did not control B. cinerea populations, and rose quality decreased as dosage increased. In a fourth experiment to determine the effect of irradiation on B. cinerea, conidia on water-agar plates exposed to dosages less than or equal to 1, 2, and 4 kGy germinated at rates of approximately 90%, 33%, and 2%, respectively, within 24 h

  15. The pre, post brachytherapy and postoperative CEA serum concentration of 53 rectal cancer patients

    International Nuclear Information System (INIS)

    Nguyen Thanh Danh; Nguyen Kim Luu; Phan Van Dan

    2008-01-01

    CEA serum concentration level of 53 rectal cancer patients was measured at moments pre, post brachytherapy (45 Gy), post surgery one week, 6 months and 12 months. Response to radiation with reduce CEA serum concentration was achieved in 20/53 patients (37,7%), mainly at staging Dukes B, C. Postoperative CEA level of patients significantly decreased, especially in resection group. (author)

  16. Donner aux travailleurs du sexe les moyens de consigner les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dans la plupart des sociétés, le travail du sexe est fortement stigmatisé, et ceux qui le pratiquent sont en butte aux reproches, à la désapprobation et à la discrimination. Par conséquent, la violence faite aux travailleurs du sexe se voit peu, et dans certains contextes, elle est même tolérée. On dispose donc de très peu de ...

  17. Communications en cas de catastrophe faisant appel aux TIC pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Communications en cas de catastrophe faisant appel aux TIC pour les collectivités vulnérables des Caraïbes. De récents événements survenus dans les Caraïbes ont mis en relief les insuffisances des mesures régionales et nationales de préparation aux catastrophes. On manque particulièrement de systèmes d'alerte ...

  18. Communication des risques reliés aux changements climatiques en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 janv. 2012 ... Il incombe bien sûr aux gouvernements locaux et nationaux de prendre les décisions relatives à l'adaptation aux changements climatiques; ils doivent toutefois les communiquer aux ménages, aux groupes communautaires et aux entreprises privées afin que ceux-ci prennent les décisions qui s'imposent ...

  19. A new BETSI test bench at CEA/Saclay

    International Nuclear Information System (INIS)

    Nyckees, S.; Adroit, G.; Delferriere, O.; Duperrier, R.; Gauthier, Y.; Gobin, R.; Harrault, F.; Mateo, C.M.; Napoly, O.; Pottin, B.; Sauce, Y.; Senee, F.; Tuske, O.; Vacher, T.

    2012-01-01

    In the nineties, CEA has undertaken to develop the production of high intensity light ion beams from plasma generated by electron cyclotron resonance (ECR). Important results were obtained with the SILHI source in pulsed or continuous mode. Presently, CEA/Saclay is now involved in the construction of different injectors dedicated to large infrastructures like IFMIF or SPIRAL2. Other installations are also interested by high intensity ion sources like ESS or FAIR. To improve and test new sources, a new test bench named BETSI (Banc d'Etudes et de Tests des Sources d'Ions) has been operating for several years. Low energy beam line diagnostics consist of a Faraday cup, cameras and a species analyzer. The SILHI emittance scanner can also be installed on the beam line. On this test bench, different permanent magnet source configurations are tested. The paper is followed by the associated poster. (authors)

  20. 2011 reporting of the risk handling at CEA

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    In 2011 CEA reported 100 events to the Authority for Nuclear Safety (ASN). 93 were graded 0 on the INES scale and 7 were graded 1. None of them had a significant impact on the staff health and the environment. 25% of these events concerned delays in the controls of safety equipment. In 2011 CEA had to manage several situations that led to a response of its crisis center: 1) the explosion of an oven belonging to the Socodei-Centraco company situated near the Marcoule Center, 2) the discovery of about 500 grenades from the first world war during digging out works in the Grenoble Center, 3) flooding due to heavy rains in the Cadarache Center, and 4) an intrusion attempt at the Cadarache Center. (A.C.)

  1. Application of VLLW management principles to the CEA research centers

    International Nuclear Information System (INIS)

    Guetat, P.

    1997-01-01

    This document describes the content of a CEA policy relating to very low level waste management elaborated in application of the waste management principles defined in France. The policy deals with very low level waste, subject to recycling, incineration or landfill disposal. It does not deal with reuse. The following principles are applicable to waste streams produced by CEA nuclear installations either during operating or dismantling activities. The policy deals only with very low level wastes (VLLW) (order of magnitude: <100 Bq/g for high energy emitters). It does not deal with low, intermediate or high level waste, which are either recycled or incinerated in nuclear industry or disposed of in the Aube surface disposal (CSA) or kept in intermediate storage, before geological disposal or any alternative final solution

  2. R and D on Transmutation at CEA: Recent Results

    International Nuclear Information System (INIS)

    Royet, V.; Delahaye, T.; Lebreton, F.; Picart, S.; Caisso, M.; Gauthe, A.; Ode, D.; Tronche, E.; Bayle, J.P; Warin, D.; Bejaoui, S.; Delage, F.

    2015-01-01

    In the field of minor actinide transmutation in future Generation IV SFR reactor, CEA investigates in priority the recycling of Americium (Am) in the radial blankets located in the outer core area (AmBB: Americium Bearing Blankets). This paper gives an overview of the recent outcomes of the R and D programme carried out at CEA in the different fields of research: from powder elaboration to experimental irradiation. Concerning the powder elaboration, several batches have been produced by the oxalic co-conversion route as well as by the Calcined Resin Microsphere Pelletizing. Different tests have been then performed for the fabrication of pellets according to the current specifications of AmBB. For these two processes, different additional developments of innovative technologies have been achieved well adapted with the processes constraints and hot cell operating. Information on irradiation programmes (MARIOS in HFR and ongoing DIAMINO in Osiris) are presented. The next steps of the programme will then be tackled. (authors)

  3. Overview of CEA research in the field of radionuclides migration

    International Nuclear Information System (INIS)

    Poinssot, Ch.; Trotignon, L.; Tevissen, E.

    2006-01-01

    This report presents a synthetic status of the researches conducted within the Nuclear Energy Division (CEA/DEN) in the field of radionuclides migration in three specific areas which have been chosen for their representativeness and potential impact: the migration of RN in PWR reactors, the migration of RN from a deep geological repository and the migration processes in the surface environments. In addition, some status is given about more generic research which is conducted in the field of RN speciation in the aqueous phase and at the interfaces and regarding chemistry / transport couplings. Additional information about the human and technical means involved in these fields of research in CEA/DEN is finally given in the Appendix. (authors)

  4. Annual report of the Association EURATOM/Cea

    International Nuclear Information System (INIS)

    Magaud, Ph.; Le Vagueres, F.

    2002-01-01

    This annual report presents research activities, which have been performed in 2002 by the French EURATOM-Cea association in the frame of the European technology program. The first section describes EFDA (European fusion development agreement) activities and related developments carried out by the association. The second one is dedicated to the underlying technology program and finally the third one presents the inertial confinement fusion activities. In each section the tasks are sorted out according to the EFDA main fields: physics (heating and current drive, remote participation, diagnostics), vessel/in-vessel (vessel/blanket, plasma facing components, remote handling), magnet, tritium breeding and materials (water cooled lithium lead blanket, helium cooled pebble bed blanket, helium cooled lithium lead blanket, reduced activation ferritic martensitic steels, advanced materials, neutron source, fuel cycle), safety and environment, system studies (power plant conceptual studies, socio-economic studies) and JET technology activities. The EURATOM-Cea association is involved in all these studies

  5. Annual report of the Association EURATOM/Cea

    Energy Technology Data Exchange (ETDEWEB)

    Magaud, Ph; Le Vagueres, F

    2002-07-01

    This annual report presents research activities, which have been performed in 2002 by the French EURATOM-Cea association in the frame of the European technology program. The first section describes EFDA (European fusion development agreement) activities and related developments carried out by the association. The second one is dedicated to the underlying technology program and finally the third one presents the inertial confinement fusion activities. In each section the tasks are sorted out according to the EFDA main fields: physics (heating and current drive, remote participation, diagnostics), vessel/in-vessel (vessel/blanket, plasma facing components, remote handling), magnet, tritium breeding and materials (water cooled lithium lead blanket, helium cooled pebble bed blanket, helium cooled lithium lead blanket, reduced activation ferritic martensitic steels, advanced materials, neutron source, fuel cycle), safety and environment, system studies (power plant conceptual studies, socio-economic studies) and JET technology activities. The EURATOM-Cea association is involved in all these studies.

  6. Preparation of one-vial reduced anti-CEA kit

    International Nuclear Information System (INIS)

    Hamada, Elena Setuko; Muramoto, Emiko; Shiraishi, Emilia Mayumi; Silva, Licia Maria Britto da; Martins, Heidi Pinto; Silva, Constanca Pagano Goncalves da

    1996-01-01

    A rapid and reliable instant reduced anti-CEA lyophilized kit for labelling with 99m Tc was developed. Each vial contains 0.5 mg of reduced anti-CEA, 40 μg of mendronate (MDP), 2.75 μg stannous fluoride (Sn F 2 ) and 15 μ g p-aminobenzoic acid (PABA). Labeling efficiency and stability were higher than 95% and were determined by instant paper chromatography. Biodistribution studies were performed in normal isogenic BALB/c mice at 4,6 and 24 hours after intravenous administration of the radiolabelled product. The maximum amount of activity was accumulated in the liver followed by intestines and kidneys. (author)

  7. Physical protection of nuclear materials and facilities in CEA

    International Nuclear Information System (INIS)

    Garnier-Gratia, M.-H.; Jorda, A.

    2001-01-01

    Full text: CEA (Commissariat a l'Energie Atomique), as nuclear operator, is responsible for the control and protection of their nuclear materials. Inside CEA, DCS (Central Security Division) is in charge of the security matters, DCS defines the CEA strategy in this field, especially in physical protection. The paper will present the physical protection strategy of CEA. DCS defines the rules and methods; the operators have to apply in order to fulfill the security objectives of CEA. CEA has to provide the regulatory authority with documents proving that it is in accordance with the requirements of the 25th July 1980 law and 12th May 1981 decree. It has to implement all the necessary means in order to achieve the results requested by the regulatory authority. All these arrangements are described in the 'license and control file'. This file should specify the facility safeguards and physical protection system. Accounting measures are also described. In this file, the petitioner has to justify its capacity for holding nuclear materials and for exercising authorized activities on them. So the organization and the installed means have to be described in this authorization file. For physical protection, containment, surveillance and physical protection measures are presented: Containment measures must prevent the unauthorized or unjustified movements of nuclear material in the framework of the authorized activities; Surveillance measures must guarantee the integrity of the containment, check that no material is exiting by an abnormal channel; Physical protection measures for the materials, the premises and the facilities are intended to protect them against malevolent actions by means of security systems. The Central Security Division has established guidelines to provide guidance to the nuclear materials holders in writing such files. Each holding unit has to establish a 'license and control file' and each CEA site establishes a 'site license and control file

  8. White Rose development plan amendment production volume increase

    International Nuclear Information System (INIS)

    2006-09-01

    In January 2001, Husky Oil Operations Limited (Husky), in joint-venture with Petro-Canada, submitted a Benefits Plan for the White Rose Development to the Canada- Newfoundland and Labrador Offshore Petroleum Board (C-NLOPB). This revised document provided the case for requesting an increase in the facility maximum daily production rate and the average annual production rate for the White Rose field from 100,000 barrels per day (bpd) as stated in the approved White Rose Development Plan to 140,000 bpd. In order to determine the potential for increasing oil production through the Floating Production, Storage and Offloading (FPSO) vessel, two things were considered, namely the proper reservoir management of the White Rose field to ensure optimum resource recovery, and the capacity of the FPSO topsides processing system and supporting utilities to accommodate increased production. This document presented a detailed review of all the implications of increased production on the South White Rose Reservoir. In addition, the results from FPSO performance testing were reviewed, including a study of options for de-bottlenecking the process plant on the topsides and capacity testing of selected process streams and support systems. Vibration analysis was conducted before and during performance testing in July 2006 and a small number of areas addressed. The document also addressed flow metering, resource management, certifying authority review, safety plan revisions, environmental effects, as well as benefits to Canada and Newfoundland. 21 tabs., 60 refs

  9. Production of desert rose seedlings in different potting media

    Directory of Open Access Journals (Sweden)

    Ronan Carlos Colombo

    2017-09-01

    Full Text Available Over the past decade the desert rose received fame in the flower market due to its striking and sculptural forms; however, the commercial production of these species is quite recent and little is known about its crop management, including substrates recommendation. The objectives of this study were to investigate the effect of different substrates on desert rose seed germination and production of its seedlings. Experiment I: freshly harvested seeds of desert rose were sown in different substrates e.g. sand, coconut fiber, semi-composted pine bark, sand + coconut fiber, semi-composted pine bark + sand and coconut fiber + semicomposted pine bark. These substrates were evaluated to study the emergence percentage of seeds, initial growth of seedlings and seedling emergence speed index (ESI. Experiment II: desert rose from the experiment I were transferred to plastic pots filled with the same substrates as in experiment I. The pH and electrical conductivity (EC of the substrates were noted every 30 days while the growth parameters of seedlings were recorded after 240 days. Results from experiment I showed higher germination rate and seedling growth in substrates containing semi-composted pine bark. Similarly, in experiment II, better quality seedlings were observed in substrates containing semi-composted pine bark. Thus, for desert rose seed germination and seedling growth, it is recommended to use substrates containing semi-composted pine bark.

  10. Back to Hegel? On Gillian Rose's critique of sociological reason.

    Science.gov (United States)

    Fuller, Brian W

    2017-08-22

    Thirty-five years ago, Gillian Rose articulated a significant critique of classical sociological reason, emphasizing its relationship to its philosophical forebears. In a series of works, but most significantly in her Hegel contra Sociology, Rose worked to specify the implications of sociology's failure, both in its critical Marxist and its 'scientific' forms, to move beyond Kant and to fully come to terms with the thought of Hegel. In this article, I unpack and explain the substance of her criticisms, developing the necessary Hegelian philosophical background on which she founded them. I argue that Rose's attempted recuperation of 'speculative reason' for social theory remains little understood, despite its continued relevance to contemporary debates concerning the nature and scope of sociological reason. As an illustration, I employ Rose to critique Chernilo's recent call for a more philosophically sophisticated sociology. From the vantage point of Rose, this particular account of a 'philosophical sociology' remains abstract and rooted in the neo-Kantian contradictions that continue to characterize sociology. © London School of Economics and Political Science 2017.

  11. Report transparency and nuclear safety 2007 CEA Marcoule

    International Nuclear Information System (INIS)

    2007-01-01

    This report presents the activities of the CEA Center of Marcoule for the year 2007. Since its creation in 1955 the center realizes industrial and scientific activities relative to the civil and military applications of the radioactivity. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the following two base activities are detailed: Atalante and Phenix. (A.L.B.)

  12. Historical review of CEA researches on uranium enrichment

    International Nuclear Information System (INIS)

    Camarcat, N.

    1997-01-01

    The various uranium enrichment processes that have been studied at the CEA since 1953 are briefly reviewed: gaseous diffusion (which led to the construction of EURODIF plant), chemical treatments (which were abandoned in 1988 for cost reasons), gaseous ultracentrifugation, electromagnetic processes, laser techniques (since 1980) and especially the SILVA technique (atomic vapour laser isotopic separation) which could take the place of the gaseous diffusion technique when the EURODIF plant will need to be renewed before 2010

  13. Sodium boiling studies at the CEA state of the art

    International Nuclear Information System (INIS)

    Girard, C.; Grand, D.; Papin, J.; Seiler, J.M.

    1979-08-01

    A description of the general approach used by the CEA to solve sodium boiling problems provides an understanding of our philosophy for code development. From the review of the main results obtained in the out-of-pile experiments, CFNa and CESAR, we deduce the main hypothesis of our basic model of sodium boiling. Our best estimate and simplified codes are briefly described and their results are compared with the experiments

  14. RELAP4/MOD-5-CEA pump coastdown experiment simulation

    International Nuclear Information System (INIS)

    Borges, R.C.; Freitas, R.L.

    1988-07-01

    Since is important the theoretical-experimental comparison to evaluate the computer codes, these paper presents the simulation with RELAP4/MOD5 Code of a loss of power energy in the pump of the ''Circuito Experimental de Agua-CEA''. From the results attained, the existing models in the Code showed to be very satisfatory quantitative and qualitative behavior of the attained experimental results. (author) [pt

  15. Report transparency and nuclear safety 2007 CEA Saclay

    International Nuclear Information System (INIS)

    2007-01-01

    This report presents the activities of the CEA Center of Saclay for the year 2007. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially two public consultation on release authorizations and the Neurospin installations, the dismantling of the 49 nuclear installation, the shutdown of the learning reactor ULYSSE are detailed. (A.L.B.)

  16. The CEA and alternative energies. 8 April 2010 press conference

    International Nuclear Information System (INIS)

    2010-01-01

    This document presents the CEA's strategy in terms of alternative energies and the various implemented research programs which mainly concern the building sector and the transport sector. After a recall of the energy and climate context, a presentation of the NTE program (Nouvelles Technologies de l'Energie, new energy technologies), the different topics and projects are presented: photovoltaic solar energy and its integration in building; batteries, hydrogen and fuel cells for applications in transports; second-generation bio-fuels

  17. Report transparency and nuclear safety 2007 CEA Cadarache

    International Nuclear Information System (INIS)

    2007-01-01

    This report presents the activities of the CEA Center of Cadarache for the year 2007. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the report discusses the beginning of the RJH reactor construction, the fourth generation reactors research programs, the implementing of la Rotonde the new radioactive wastes management installation, the renovation of the LECA. (A.L.B.)

  18. Qualitative comparison of Dutch and Ethiopian Rose production systems. Why Dutch rose growers move to African Nations and what consequences does this migration have?

    NARCIS (Netherlands)

    Vries de, Willem

    2010-01-01

    Summary The rose cultivation is used as a study example in this report to facilitate the understanding of the overall differences between the cultivation of agricultural products in the Netherlands and those in warmer countries. The Dutch rose cultivat

  19. CEA A BIOCHEMICAL MARKER FOR DIAGNOSIS AND PROGNOSIS OF GASTROINTESTINAL CANCER

    Directory of Open Access Journals (Sweden)

    Prathibha

    2016-02-01

    Full Text Available Serum tumor markers (TM are widely used for diagnosis and monitoring of treatment of cancer. Carcinoembryonic Antigen (CEA is one of the most widely investigated tumor markers in gastrointestinal (GI cancers. Estimation of circulating tumor markers is a non- invasive quantitative method. Serum levels of CEA were studied for diagnosis and prognosis of gastrointestinal malignancies. 140 subjects were undertaken out of which 35 normal and remaining 105 were GI cancer patients. Serum levels of CEA were analyzed by Enzyme Linked Immunosorbent Assay (ELISA. Result of serum CEA levels of the GI cancer patients and normal subjects were analyzed statistically. It was observed that there was significant increase in (P <0.01 in CEA levels of oesophagus, stomach and colon cancer patients as compared to normal subjects. The levels of CEA decreased significantly after the surgery but the decrease in levels of CEA was not up to the levels as normal control subjects.

  20. CEA - Nuclear Energy Division. Report on Sustainable Radioactive Waste Management

    International Nuclear Information System (INIS)

    2012-12-01

    The Sustainable Radioactive Waste Management Act of June 28, 2006, specified clear guidelines for spent nuclear fuel management. It states two complementary principles: - The policy of treating and recycling spent nuclear fuel is valid for reducing the quantity and toxicity of suitably packaged ultimate radioactive waste-forms. - The reference process for high-activity and long-lived ultimate waste is deep geological disposal. The report prepared by the CEA in response to these requirements was completed after several years of work in cooperation with the other French actors in this field (EDF, AREVA) and with contribution of the CNRS and Andra. It addresses the following topics in several volumes: n guidelines for research on 4. generation systems, and a description of the various systems examined; - the results of research coordinated by the CEA on partitioning and transmutation of long-lived radioactive elements; - choices proposed for the Astrid integrated technology demonstrator - a sodium-cooled fast reactor (SFR) - and a reasonable timetable for its construction; - a review of research conducted around the world on 4. generation systems based on fast neutron reactors (FNRs). The principal results and findings compiled by the CEA from these studies are summarized in this document

  1. APR1400 CEA Withdrawal at Power Accident Analysis using KNAP

    International Nuclear Information System (INIS)

    Lee, Dong-Hyuk; Yang, Chang-Keun; Kim, Yo-Han; Sung, Chang-Kyung

    2006-01-01

    KEPRI (Korea Electric Power Research Institute) has been developing safety analysis methodology for non- LOCA (Loss Of Coolant Accident) analysis of OPR1000 (Optimized Power Reactor 1000, formerly KSNP). The new methodology, named KNAP (Korea Non-LOCA Analysis Package), uses RETRAN as the main system analysis code. RETRAN code is a non- LOCA safety analysis code developed by EPRI. The new methodology will replace existing CE (Combustion Engineering) supplied codes and methodologies currently used in non-LOCA analysis of OPR1000. In this paper, we apply KNAP methodology to APR1400 (Advanced Power Reactor 1400). The CEA (Control Element Assembly) withdrawal at power accident is one of the 'reactivity and power distribution anomalies' events and the results are typically described in the chapter 15.4.2 of SAR (Safety Analysis Report). The APR1400 has been designed to generate 1,400MWe of electricity with advanced features for greatly enhanced safety and economic goals. The CEA withdrawal at power analysis in APR1400 SSAR (Standard Safety Analysis Report) is analyzed with CESEC-III computer code. In this study, to confirm the applicability of the KNAP methodology and code system to APR1400, CEA withdrawal at power accident is analyzed using RETRAN code and it is compared with results from APR1400 SSAR

  2. Regarding the old Cea factory of the Bouchet

    International Nuclear Information System (INIS)

    Anon

    1997-10-01

    This article si devoted to the Cea site of the Bouchet. Radiation monitoring have been made and the information about it, given to the populations around the site. The wastes with a value upper than this one chosen for low activity wastes have been sent to the storage center of Manche plant, the other ones whom activity level was lower than this one advocated for low level radioactive wastes were used for the base of A87 motorway. The two little rivers have been cleaned out and the sediments tipped out in the decantation basin of the Cea site. Radiation monitoring for the radon have to be made to control the right progress of these decontamination operations. All these operations have been made in dialogue with S.N.P.E.( the national society of powders and explosives), the D.R.I.R.E.( regional direction of research industry and environment), O.P.R.I. (office of protection against ionizing radiations) and the Cea. (N.C.)

  3. Ior-CEA-1: Labelling, quality control and clinical evaluation

    International Nuclear Information System (INIS)

    Pimentel, G.J.

    1998-01-01

    Within the Co-ordinated Programme on Labelling, Quality Control and Evaluation of Monoclonal Antibodies, the IAEA has made a great effort to expand efficient labelling methods, mainly those with radioisotopes which have been used for radioimmunoscintigraphy. In this sense, more recently 99 Tc m has been mostly employed in the majority of the investigations due to its ideal physical characteristics. Efficient labelling of monoclonal antibodies depends on a number of factors including the method and way of the label incorporation into the protein. During the last years several direct labelling approaches have been developed, which led to attain simple and inexpensive methods for medical practice, as well as safe and stable techniques which bring accurate and good quality images. Accordingly, this paper describes the results obtained during last five years which come from the comparison among different labelling systems, passing through the quality control to test the labelled monoclonal stability and the protein bioreactivity, to continue in the clinical evaluation of ior-CEA-1, as well as the evaluation of other antibodies. Up to now we have evaluated more than 70 patients with the anti-CEA monoclonal antibody (ior-CEA-1), examined in different clinical assays such as: pilot, phase I-II and extensive phase III-IV trials, whose results are encouraging. It confirms that the employed labelling approach was safe and adequate

  4. Mutation breeding of roses at the National Botanic Gardens

    International Nuclear Information System (INIS)

    Gupta, M.N.

    1978-01-01

    Results of the work done at the National Botanic Garden, Lucknow, on radiation induced somatic mutations in roses are reported. Bud-wood of various rose cultivars was exposed to radiation doses ranging from 2 to 8 kR of gamma rays. In general, irradiation delayed sprouting of rose buds and decreased bud-take. Budded plants after irradiation showed decrease in survival and height of plants and also decrease in percentage of essential oil in flowers. Various abnormalities in shape, size and colour of leaves were observed. These effects were enhanced by increase in radiation dose. An explanation of these effects is attempted on the basis of injurious biochemical and cytological changes induced in plant cells by radiation. Somatic mutants isolated and stabilised are described. (M.G.B.)

  5. Tocopherols in rose hips (Rosa spp.) during ripening.

    Science.gov (United States)

    Andersson, Staffan C; Olsson, Marie E; Gustavsson, Karl-Erik; Johansson, Eva; Rumpunen, Kimmo

    2012-08-15

    Rose hips are used as a food ingredient and in health products. They are rich in various bioactive compounds such as carotenoids and vitamin C, but data on their vitamin E content (tocopherols and tocotrienols) are limited. In this study, four different species of Rosa were analysed for tocopherol and tocotrienol content during ripening in three different years. Only α- and γ-tocopherol were found in the fleshy parts of the rose hips, and the tocopherol content and vitamin E activity varied depending on date of harvesting, species and year. The amount of vitamin E activity differed between species of Rosa and years, whereas the changes during ripening were relatively small. The choice of species must be considered if tocopherol content is to be optimised when rose hips are used as a food ingredient. Copyright © 2012 Society of Chemical Industry.

  6. Rose hip (Rosa canina L: A functional food perspective

    Directory of Open Access Journals (Sweden)

    Cui Fan

    2014-12-01

    Full Text Available Rose hip (Rosa canina L. is the pseudo-fruit of the rose plant, which is widely known as a valuable source of polyphenols and vitamin C. Both in vivo and in vitro studies have demonstrated that this fruit exhibits anti-inflammatory, antioxidant, and antiobesogenic activities. The health benefits of Rose hip (RH have been attributed to its wide range of bioactive compounds including the anti-inflammatory galactolipid: (2S-1,2-di-O-[(9Z,12Z,15Z-octadeca-9,12,15-trienoyl]-3-O-β-D galactopyranosyl glycerol (GOPO, vitamin C, phenolics, lycopene, lutein, zeaxanthin, and other carotenoids. As cyclooxygenase inhibitors, RH compounds may reduce the risk of cancer, heart disease, and various inflammatory conditions. The aim of this review is to present an overview of the functional, medical, and physiological properties of RH.

  7. Rosácea fulminante: relato de caso

    Directory of Open Access Journals (Sweden)

    José Otávio Alquezar Gozzano

    2016-10-01

    Full Text Available Introdução: Rosácea fulminante (RF ou pioderma facial é uma doença rara, descrita em 1940 por Kierland e O’Leary. É considerada uma variante extrema de rosácea conglobata, esta, consiste em formação de placas e abscessos hemorrágicos na pele. A RF tem sua etiologia desconhecida, porém há teorias que relacionam seu acometimento com a variação de hormônios femininos e a ingestão de vitamina B12. A RF é frequente em mulheres, principalmente pós- adolescentes. Apresenta-se abruptamente na face, amiúde na região mento- mandibular, através de pápulas inflamatórias, pústulas, cistos e nódulos com comedões escassos ou inexistentes, além de abcessos, sem manifestações sistêmicas e com a recidiva rara. Seu diagnóstico é fundamentalmente clínico, apenas com a história do paciente, sem necessidade de exames complementares. Para o tratamento, são utilizados corticoides orais, isotretinoína oral e antibióticos a fim de minimizar as sequelas físicas e psicológicas. Objetivo: Relatar caso de paciente com diagnóstico de rosácea fulminante. Metodologia: Paciente diagnosticada com rosácea fulminante atendida em serviço ambulatorial e revisão de literatura. Relato de caso: Paciente do sexo feminino, 19 anos, refere lesões súbitas em face há uma semana. Nega quadro acneico anterior, histórias de alergias e outras comorbidades. Relata ausência de uso de anticoncepcionais orais há 5 meses e data de última menstruação há 3 semanas, sem atraso menstrual. Ao exame: pápulas eritematosas e pústulas, além de pequenos nódulos inflamatórios na face. Hipótese diagnóstica: RF. Como conduta, foi prescrito tetraciclina. Conclusões: A RF é uma forma infrequente de rosácea, sendo importante o diagnóstico precoce e tratamento eficaz, a fim de melhorar a qualidade de vida do paciente.

  8. Production technology of 131I-rose bengal

    International Nuclear Information System (INIS)

    Hradilek, P.; Miklik, M.; Kopicka, K.; Kronrad, L.

    1983-01-01

    A detailed description is presented of the production equipment and production process used for Rose Bengal labelled with 131 I designed for use in nuclear medicine. The apparatus was installed in the semi-hot cell laboratory of the Nuclear Research Institute at Rez. The processed activity is around 20 GBq, the average yield of the ion exchange reaction between non-radioactive Rose Bengal and 131 I-labelled sodium iodide is 90%. The unreacted active sodium iodide is separated and the resulting product is diluted and processed into a drug presentation, sterilized and after random control is distributed in 14 days intervals to medical workplaces. (M.D.)

  9. Rapid labelling of rose bengal and iothalamate with radioiodine

    International Nuclear Information System (INIS)

    Alvarez, J.

    1981-01-01

    Rapid and simple methods for tagging rose bengal and iothalamate with radioactive iodine are proposed. In both cases, the reaction takes place in a penicillintype vial. In the first method, Chloramine-T, was added to a vial containing rose bengal and radioiodide. Tagging iothalamate requires heating a mixture of iothalamate and radioactive iodine in the autoclave. A high radiochemical yield was obtained in the two procedures. This obviated the need of separating the small amount of free radioiodine present in the final product. (author)

  10. Fast radioiodination of rose bengal at room temperature

    International Nuclear Information System (INIS)

    Verbruggen, R.F.

    1987-01-01

    Polyhalogenated dyes based on aromatic ring systems such as fluorosceins have been used for the evaluation of hepatobiliary function since 1909. In 1955 rose bengal was radioiodinated and a radiocontrastdye become a radiopharmaceutical. In the present study an improved method, based on the chloramine-T method, has been developed for labelling rose bengal. This method was chosen for its short reaction time, its mild conditions and its high yield. The optimum values of the reaction parameters have been determined, and resulted in a slightly higher yield, within a shorter time and without breakdown products being present

  11. Intensified follow-up in colorectal cancer patients using frequent Carcino-Embryonic Antigen (CEA) measurements and CEA-triggered imaging : Results of the randomized "CEAwatch" trial

    NARCIS (Netherlands)

    Verberne, C. J.; Zhan, Z.; van den Heuvel, E.; Grossmann, I.; Doornbos, P. M.; Havenga, K.; Manusama, E.; Klaase, J.; van der Mijle, H. C. J.; Lamme, B.; Bosscha, K.; Baas, P.; van Ooijen, B.; Nieuwenhuijzen, G.; Marinelli, A.; van der Zaag, E.; Wasowicz, D.; de Bock, G. H.; Wiggers, T.

    Aim: The value of frequent Carcino-Embryonic Antigen (CEA) measurements and CEA-triggered imaging for detecting recurrent disease in colorectal cancer (CRC) patients was investigated in search for an evidence-based follow-up protocol. Methods: This is a randomized-controlled multicenter prospective

  12. Evaluation of the concrete shield compositions from the 2010 criticality accident alarm system benchmark experiments at the CEA Valduc SILENE facility

    International Nuclear Information System (INIS)

    Miller, Thomas Martin; Celik, Cihangir; Dunn, Michael E; Wagner, John C; McMahan, Kimberly L; Authier, Nicolas; Jacquet, Xavier; Rousseau, Guillaume; Wolff, Herve; Savanier, Laurence; Baclet, Nathalie; Lee, Yi-kang; Trama, Jean-Christophe; Masse, Veronique; Gagnier, Emmanuel; Naury, Sylvie; Blanc-Tranchant, Patrick; Hunter, Richard; Kim, Soon; Dulik, George Michael; Reynolds, Kevin H.

    2015-01-01

    In October 2010, a series of benchmark experiments were conducted at the French Commissariat a l'Energie Atomique et aux Energies Alternatives (CEA) Valduc SILENE facility. These experiments were a joint effort between the United States Department of Energy Nuclear Criticality Safety Program and the CEA. The purpose of these experiments was to create three benchmarks for the verification and validation of radiation transport codes and evaluated nuclear data used in the analysis of criticality accident alarm systems. This series of experiments consisted of three single-pulsed experiments with the SILENE reactor. For the first experiment, the reactor was bare (unshielded), whereas in the second and third experiments, it was shielded by lead and polyethylene, respectively. The polyethylene shield of the third experiment had a cadmium liner on its internal and external surfaces, which vertically was located near the fuel region of SILENE. During each experiment, several neutron activation foils and thermoluminescent dosimeters (TLDs) were placed around the reactor. Nearly half of the foils and TLDs had additional high-density magnetite concrete, high-density barite concrete, standard concrete, and/or BoroBond shields. CEA Saclay provided all the concrete, and the US Y-12 National Security Complex provided the BoroBond. Measurement data from the experiments were published at the 2011 International Conference on Nuclear Criticality (ICNC 2011) and the 2013 Nuclear Criticality Safety Division (NCSD 2013) topical meeting. Preliminary computational results for the first experiment were presented in the ICNC 2011 paper, which showed poor agreement between the computational results and the measured values of the foils shielded by concrete. Recently the hydrogen content, boron content, and density of these concrete shields were further investigated within the constraints of the previously available data. New computational results for the first experiment are now available

  13. Towards a unified genetic map of diploid roses

    NARCIS (Netherlands)

    Spiller, M.; Hibrand-Saint Oyant, L.; Tsai, C.; Byrne, D.H.; Smulders, M.J.M.; Foucher, A.L.J.L.; Debener, T.

    2011-01-01

    We have constructed the first integrated consensus map (ICM) for rose, based on the information of four diploid populations and more than 1,000 initial markers. The single population maps are linked via 59 bridge markers, on average 8.4 per linkage group (LG). The integrated map comprises 597

  14. Going Back to School: An Interview with Mike Rose

    Science.gov (United States)

    Adams, Peter

    2017-01-01

    Mike Rose is a professor in the UCLA Graduate School of Education and Information Studies. He has taught in a wide range of educational settings - from elementary school to adult literacy and job training programs--and has directed an Educational Opportunity (EOP) tutorial center. He is an author and member of the National Academy of Education and…

  15. Erythrocyte antioxidant protection of rose hips (Rosa spp.).

    Science.gov (United States)

    Widén, C; Ekholm, A; Coleman, M D; Renvert, S; Rumpunen, K

    2012-01-01

    Rose hips are popular in health promoting products as the fruits contain high content of bioactive compounds. The aim of this study was to investigate whether health benefits are attributable to ascorbic acid, phenols, or other rose-hip-derived compounds. Freeze-dried powder of rose hips was preextracted with metaphosphoric acid and the sample was then sequentially eluted on a C(18) column. The degree of amelioration of oxidative damage was determined in an erythrocyte in vitro bioassay by comparing the effects of a reducing agent on erythrocytes alone or on erythrocytes pretreated with berry extracts. The maximum protection against oxidative stress, 59.4 ± 4.0% (mean ± standard deviation), was achieved when incubating the cells with the first eluted meta-phosphoric extract. Removal of ascorbic acid from this extract increased the protection against oxidative stress to 67.9 ± 1.9%. The protection from the 20% and 100% methanol extracts was 20.8 ± 8.2% and 5.0 ± 3.2%, respectively. Antioxidant uptake was confirmed by measurement of catechin by HPLC-ESI-MS in the 20% methanol extract. The fact that all sequentially eluted extracts studied contributed to protective effects on the erythrocytes indicates that rose hips contain a promising level of clinically relevant antioxidant protection.

  16. Genetic Diversity of Rose germplasm based on RAPD analysis

    African Journals Online (AJOL)

    AHSAN IQBAL

    2012-06-12

    Jun 12, 2012 ... identification and analysis of genetic variation within a collection of 4 species and 30 accessions of rose using RAPD analysis technique. The results showed the molecular distinctions among the ... that range in colour from white and yellow to many shades of pink and red have been developed. Since.

  17. Tips From Former Smokers – Rose

    Centers for Disease Control (CDC) Podcasts

    2014-07-07

    Rose developed lung cancer from smoking cigarettes and needed surgery. She talks about the difficulties she faced recovering from surgery.  Created: 7/7/2014 by Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion.   Date Released: 7/7/2014.

  18. Factors affecting the germination of hybrid rose achenes

    NARCIS (Netherlands)

    Vries, De D.P.; Dubois, L.A.M.

    2015-01-01

    The smooth germination of mature Hybrid rose achenes is hampered by (i) hardseededness (HS), (ii) primary dormancy (PD) and (iii) germination polymorphism (GP). HS is owing to the hard pericarp. PD is, in principle, a natural phenomenon that protects the seeds from precocious germination. For

  19. Scion - rootstock relationships and root behaviour in glasshouse roses

    NARCIS (Netherlands)

    Fuchs, H.W.M.

    1994-01-01

    In the Netherlands, the cultivation of cut roses in the glasshouse is commonly carried out yearround. Most cultivars are grown on a rootstock. The first part of this study investigates various rootstocks for their ability to influence production and quality throughout the year. The mutual influence

  20. Rose Windows: A Bridge Between Heaven And Earth

    OpenAIRE

    Gaiko, Jennifer Lynn

    2017-01-01

    The rose window is a bridge between heaven and earth, a spiritual encounter, and an expression from within to allow the love of joy. Ornament and beauty are the adoration of light. Layers of composition and layers of light allow form to follow feeling through the structural repetition and thought of light as a material itself. MARCH

  1. Rose bengal-sensitized nanocrystalline ceria photoanode for dye ...

    Indian Academy of Sciences (India)

    The bandgap of 2.93 eV is calculated using UV–visible ... Keywords. Wide bandgap; dye-sensitized solar cells; CeO2; rose bengal dye. 1. ... and renewable energy, its high-cost production and installa- tion excludes direct commercial use. It is an urgent require- .... surface leads to oxygen vacancies and defects, whose influ-.

  2. PEMUNGUTAN MINYAK ATSIRI MAWAR (Rose Oil DENGAN METODE MASERASI

    Directory of Open Access Journals (Sweden)

    Astrilia Damayanti

    2013-05-01

    Full Text Available Minyak mawar merupakan salah satu produk minyak bunga yang memungkinkan diproduksi di Indonesia dengan kualitas ekspor. Manfaat dari minyak mawar adalah untuk parfum, kosmestik, dan obat-obatan. Minyak mawar dapat diproduksi dengan menggunakan metode diantaranya maserasi. Tujuan penelitian ini adalah mengetahui rendemen minyak atsiri mawar merah (Rosa damascena dan komponen minyak atsiri yang terambil dengan etanol dan n-heksana. Bahan baku yang digunakan berupa mahkota bunga mawar sebanyak 50 gram yang dipotong kecil-kecil, kemudian direndam dalam pelarut dengan perbandingan 1:3. Pelarut yang digunakan yaitu etanol dan n-heksana. Proses maserasi dilakukan dengan pengadukan selama 1 menit secara manual pada suhu ruang dan didiamkan selama 12 jam di tempat tertutup dan gelap (tanpa terkena cahaya. Hasil maserasi berupa ekstrak mawar dipisahkan dengan cara penyaringan dan pemerasan bunga. Filtrat yang mengandung minyak bunga mawar dievaporasi dengan  rotary vacuum evaporator. Maserasi menggunakan etanol pada suhu 60ºC selama 20 menit, sedangkan maserasi menggunakan n-heksana pada suhu 55 ºC selama 10 menit. Minyak atsiri hasil maserasi bunga mawar merah dilakukan uji GC-MS. Komponen utama minyak atsiri dari bunga mawar dengan pelarut etanol dan pelarut n-heksana secara berurutan adalah phenyl ethyl alcohol (2,73% dan (31,69%. Rendemen hasil maserasi minyak bunga mawar dengan pelarut etanol adalah 8,76%, sedangkan pelarut n-heksana menghasilkan 0,34 %. Rose oil is one of the flower oil products which is potentially produced in Indonesia with export quality. The uses of rose oils are for perfume, cosmestics, and medicine. Rose oil can be produced using methods such as maceration. The purpose of this reasearch was to determine the yield of essential oil of red roses (Rosa damascena and the essential oil components taken using ethanol and n-hexane. The raw material used was 50 grams of red roses which subsequently soaked into solvent with

  3. Producing energy without greenhouse effect gases: the CEA action

    International Nuclear Information System (INIS)

    2008-01-01

    Major actor in the domain of new energy technologies, the CEA manages the french research on the hydrogen and the fuel cells. It is also implied with INES (National Institute for the Solar Energy) in the photovoltaic and thermal solar. With the IFP (French Petroleum Institute), it manages research on biofuels. Of course the thermonuclear fusion, for the development of the energy of the future, is in its research program too. This information document presents the possibilities of these energies and the associated research programs. (A.L.B.)

  4. The 1988 CEA progress report on laser research programs

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    The 1988 CEA progress report, concerning laser investigations, is presented. The aim of the research programs on laser/matter interactions is to contribute to the military application works on this field, as well as to the development of the inertial confinement fusion physics. The activities related to the installation and starting of Phebus laser system are described. The development of soft x-ray instrumentation are included. In the field of numerical simulations, the improvement of FCI 1 and 2 codes are extended for increasing the field of the physical phenomena taken into account and getting their use more flexible to the experiment analysis [fr

  5. Upgrading of aerosol generators for use at Cadarache (CEA)

    International Nuclear Information System (INIS)

    Kaspar, G.; Loescher, H.; Ruhmann, H.

    1988-11-01

    The aerosol generators developed for, and used in, the DEMONA project have been further developed for the FUCHIA project run by CEA. As a result of these efforts the generators have been uprated for fifty-hour continuous generation of SnO 2 and CsOH aerosols at a rate of 10 g/min against a system pressure of 5 bar. Significantly higher feed rates may be possible but were not required. The development objective was fully satisfied, the generators are ready for service in the FUCHIA project. (orig.). 1 ref., 2 tabs., 9 figs [de

  6. Atualidades e perspectivas das Anonáceas no mundo

    OpenAIRE

    São José,Abel Rebouças; Pires,Mônica de Moura; Freitas,Afonso Lúcio Gomes Estrela de; Ribeiro,Denis Pereira; Perez,Luis Alfonso Aguilar

    2014-01-01

    Várias espécies da família Annonaceae produzem frutos comestíveis cultivados em pomares comerciais ou coletados de forma extrativista, em diversas partes do mundo. O gênero Annona possui elevado número de espécies nativas, no entanto poucas produzem frutos comestíveis. Algumas são cultivadas comercialmente, outras são obtidas de forma extrativista. As principais anonáceas cultivadas no mundo são: Annona muricata, Annona squamosa e Annona cherimola, com destaque também para a atemoia (híbrido ...

  7. Atomic Energy Commission (CEA) dismantling experience review and perspectives

    International Nuclear Information System (INIS)

    Barre, J.Y.

    1992-01-01

    Reorganization and dismantling have been part of the CEA's facility renewal process for more than twenty years now. Many facilities have already been downrated or will be in the near future. The strategy developed so far is founded on acquired experience, on the basis of which it may be said that: nuclear facilities are reversible in full and strict compliance with safety and security rules; a field of competence has been developed that will help French industries to land on their feet when the time comes on the dismantling market; public opinion has been informed as to the soundness of the energy alternatives chosen

  8. Sertula Florae Colombiae – XV: Nuevas Melastomatáceas

    Directory of Open Access Journals (Sweden)

    Uribe Uribe Lorenzo

    1980-09-01

    Full Text Available El notable aumento de las colecciones del Herbario Nacional Colombiano muestran la riqueza de la flora melastomatácea de Colombia. Uno de los géneros más ricos y más bien caracterizados es Blakea. En este artículo describo dos nuevas especies muy interesantes. Dejo consignada mi gratitud para elnotable dibujante, don Silvio Fernández Valencia, a quien se deben las magníficas ilustraciones y muchos datos y mediciones de órganos pequeñísimos, que facilitaron  las descripciones exactas de las plantas.

  9. Dexamethasone minimizes the risk of cranial nerve injury during CEA.

    Science.gov (United States)

    Regina, Guido; Angiletta, Domenico; Impedovo, Giovanni; De Robertis, Giovanni; Fiorella, Marialuisa; Carratu', Maria Rosaria

    2009-01-01

    The incidence of cranial and cervical nerve injury during carotid endarterectomy (CEA) ranges from less than 7.6% to more than 50%. Lesions are mainly due to surgical maneuvers such as traction, compression, tissue electrocoagulation, clamping, and extensive dissections. The use of dexamethasone (DEX) and its beneficial effects in spinal cord injuries have already been described. We investigated whether DEX could also be beneficial to minimize the incidence of cranial and cervical nerve injury during CEA. To evaluate whether dexamethasone is able to reduce the incidence of cranial nerve injuries. From March 1999 through April 2006, 1126 patients undergoing CEA because of high-grade carotid stenosis were enrolled and randomized by predetermined randomization tables into two groups. The first group, "A", included 586 patients that all received an intravenous administration of dexamethasone following a therapeutic scheme. The second group, "B", included 540 control subjects that received the standard pre- and postoperative therapy. All patients were submitted to a deep cervical plexus block, eversion carotid endarterectomy, and selective shunting. Three days after the operation, an independent neurologist and otorhinolaryngologist evaluated the presence of cranial nerve deficits. All patients (group A and group B) showing nerve injuries continued the treatment (8 mg of dexamethasone once in the morning) for 7 days and were re-evaluated after 2 weeks, 30 days, and every 3 months for 1 year. Recovery time took from 2 weeks to 12 months, with a mean time of 3.6 months. The chi(2) test was used to compare the two groups and to check for statistical significance. The incidence of cranial nerve dysfunction was higher in group B and the statistical analysis showed a significant effect of dexamethasone in preventing the neurological damage (P = .0081). The incidence of temporary lesions was lower in group A and the chi(2) test yielded a P value of .006. No statistically

  10. Status of CEA studies on desalination on July 1, 1967

    International Nuclear Information System (INIS)

    Huyghe, J.; Vignet, P.; Courvoisier, P.; Frejacques, M.; Coriou, M.; Agostini, M.; Lackme, C.; CORPEL, M.; Thiriet, L.

    1967-01-01

    This publication contains a set of articles reporting studies on desalination performed within the CEA: preliminary draft of a desalination plant coupled with a nuclear reactor; the reverse osmosis; corrosion problems in seawater desalination plants; optimisation program of a distillation-based seawater desalination plant; activities of the department of analysis and applied chemistry in the field of desalination; abstract of a lecture on studies on price functions; studies of the department of steady isotopes on the formation of tartar depositions and their prevention; studies performed within the thermal transfer department

  11. Analogue studies at the french atomic commission (CEA)

    International Nuclear Information System (INIS)

    Petit, J.C.

    1986-06-01

    The different research activities of the French Atomic Energy Commission in the analogue study field are presented. Most of them are conducted in collaboration with major research organisations, both french and international. In fact, the scientific community has been associated to these programmes at different steps of their realisation. The brief description presented illustrates the great diversity and complementarity of actions conducted by CEA for better understanding, through the study of natural analogues, the basic processes that will rule the long term behaviour of high level radwaste materials in a repository and hence contributing to hopefully guaranty disposal safety

  12. Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers

    OpenAIRE

    Sajid, Khan Mohammad; Chaouachi, Kamal; Mahmood, Rubaida

    2008-01-01

    Abstract Background We have recently published some work on CEA levels in hookah (also called narghile, shisha elsewhere) and cigarette smokers. Hookah smokers had higher levels of CEA than non-smokers although mean levels were low compared to cigarette smokers. However some of them were also users of other tobacco products (cigarettes, bidis, etc.). Objectives To find serum CEA levels in ever/exclusive hookah smokers, i.e. those who smoked only hookah (no cigarettes, bidis, etc.), prepared b...

  13. Postoperative serum CEA level as predictive factor for survival in patients with colorectal cancer

    International Nuclear Information System (INIS)

    Lemberger, J.J.; Bogar, M.L.; Takacs Kucsera, M.F.; Csernetics, I.F.

    2002-01-01

    Aim: It is known that routine follow-up of patients with resected colorectal cancer includes serial CEA determinations. In this retrospective study we have investigated relationship between CEA level and survival and whether achieved results enable differentiation of tumors with slow and rapid growth. Material and Methods: Mainly between 1995 and 1999 periodic CEA determination by IRMA were performed in 269 patients after curative resection of colorectal carcinoma. Number of CEA determination/patient were 2-16(median 6). Survival ranged 4,5 and>249,7 months. Based on CEA results patients were divided in group with normal (<10ng/ml) and elevated (=10ng/ml) values regardless of postoperative treatment. Survival curves were computed by Kaplan-Meier method and difference was evaluated by logrank test and difference between proportions. Results:Normal end elevated CEA was found in 193 and 76 patients, respectively. The difference of survival curves between patients with normal and elevated CEA are highly significant (p<0,0001). However, only 10 months after tumor resection is the difference between survived proportions significant suggesting already presence of CEA produced micrometastases contributing to progression of neoplastic process. The mean survival time at normal and elevated CEA values are 142,54±17,86(median 128,60±24,04) and 34,15±4,28 (median 25,20±1,97) months, respectively. No significant difference of survival was found regarding tumor localization. Conclusion:The results show that with regard to CEA level it is possible to divide colorectal tumors on marker negative and positive. Marker negative are with slower growth and relatively good prognosis. Marker positive are associated with elevated CEA level and with considerable shorter survival. Postoperative CEA level is valuable parameter in prediction of patient's outcome

  14. Evaluation of the nuclear installations safety of the CEA in 1998

    International Nuclear Information System (INIS)

    Laverie, M.

    1999-09-01

    Michel Laverie, Director of the nuclear safety and quality at the Cea, took stoke of the CEA nuclear installations in 1998. After a recall of the nuclear safety policy and organization, the author presents the risks factors bound to the CEA activities as the dismantling, the wastes and the human factors. A last part is devoted to the list of the accidents occurred during 1998 in the nuclear installations. Tables and statistics illustrate this analysis. (A.L.B.)

  15. Prognostic impact of carcinoembryonic antigen (CEA) on patients with metastatic pancreatic cancer: A retrospective cohort study.

    Science.gov (United States)

    Imaoka, Hiroshi; Mizuno, Nobumasa; Hara, Kazuo; Hijioka, Susumu; Tajika, Masahiro; Tanaka, Tsutomu; Ishihara, Makoto; Hirayama, Yutaka; Hieda, Nobuhiro; Yoshida, Tsukasa; Okuno, Nozomi; Shimizu, Yasuhiro; Niwa, Yasumasa; Yamao, Kenji

    2016-01-01

    Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers, and its level is increased in 30-60% of patients with pancreatic cancer (PC). However, little is known about the implications of CEA as a prognostic marker in metastatic PC. The purpose of this study was to examine the usefulness of CEA levels as a prognostic marker in patients with metastatic PC. We conducted a retrospective cohort study using data from a computerized database. A total of 433 patients with metastatic disease were analyzed. Median overall survival (OS) was significantly shorter for patients with high CEA (>5 ng/ml) than with normal CEA (≤5 ng/ml) (6.8 vs. 10.3 months, respectively; p CEA level was an independent predictive factor for OS (hazard ratio [HR], 1.81; 95% confidence interval [CI], 1.45-2.26). In the high CEA group, OS in patients treated with combination chemotherapy was similar to that with single-agent chemotherapy (median, 7.1 vs. 6.8 months; HR for OS, 0.99; 95% CI, 0.71-1.40). The present results show that CEA level is an independent prognostic factor in patients with metastatic PC. A combination chemotherapy regimen may offer modest survival benefit in patients with high CEA. Copyright © 2016 IAP and EPC. Published by Elsevier B.V. All rights reserved.

  16. Influencing factors on the serum carcinoembryonic antigen (CEA) in benign liver diseases

    International Nuclear Information System (INIS)

    Pompecki, R.; Mehl, H.; Fehr, R.; Braun, H. von

    1982-01-01

    Carcinoembryonic antigen (CEA) was determined in the sera of 452 patients with benign liver diseases by radioimmunoassay (CEA-RIA Kit, Abbott). The CEA-level exceeded 2.5 ng/ml in 39 percent and 5.0 ng/ml in 9 percent of the cases. Independent influences of age, nicotin, and alcohol consumption and connective tissue proliferation of the liver on the CEA level were demonstrated and quantified by two- and higher-dimensional contingency table analysis. Toxic liver diseases were combined with elevated serum CEA values more often than inflammatory diseases. This aspect could not be investigated independently since there were only a few cases of toxic liver diseases without alcohol consumption. Sex and relative body weight do not seem to affect the CEA level. Additional diseases of the gastrointestinal tract or the cardiovascular system did not influence the serum CEA level in liver diseases. Therefore, in patients with benign liver diseases, an elevated serum CEA level indicates increased proliferation of the connective tissue. Age, nicotin, and alcohol consumption have to be considered independently in the clinical judgement of elevated serum CEA levels, irrespective of the underlying disease. (orig.) [de

  17. Appui aux transitions dans le monde arabe | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    étudieront l'évolution du rôle de l'État face aux enjeux économiques et sociaux; - appuieront les ... ARI Centre pour une initiative arabe de réforme. Institution Country. France ... New funding opportunity for gender equality and climate change.

  18. Adaptation aux changements climatiques dans le bassin versant de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... hydrologiques et agronomiques, les chercheurs étudieront l'évolution de la ... de coopération scientifique et technologique en appui aux projets de recherche ... de l'Institut d'étude du développement international de l'Université McGill.

  19. Recherche sur l'adaptation aux changements climatiques

    International Development Research Centre (IDRC) Digital Library (Canada)

    Corey Piccioni

    consortiums travaillent dans des zones vulnérables aux changements climatiques en Afrique et en Asie, notamment dans les bassins hydrographiques alimentés .... Le projet de recherche Pathways to Resilience in Semi-Arid Economies (PRISE) vise à réduire les risques et à opti- miser les possibilités de développement ...

  20. Inobservance therapeutique aux anti-retroviraux chez les personnes ...

    African Journals Online (AJOL)

    Buts : Rechercher les facteurs psychologiques ou psychosociaux responsables de l'inobservance thérapeutique (IBT) aux antiretroviraux (ARV) Méthodologie : Il s'agit d'une étude transversale sur 06 mois (mai - octobre 2008) menée au centre de promotion sociale à Lomé chez les personnes vivant avec le VIH (PVVIH) ...

  1. AUX: a scripting language for auditory signal processing and software packages for psychoacoustic experiments and education.

    Science.gov (United States)

    Kwon, Bomjun J

    2012-06-01

    This article introduces AUX (AUditory syntaX), a scripting syntax specifically designed to describe auditory signals and processing, to the members of the behavioral research community. The syntax is based on descriptive function names and intuitive operators suitable for researchers and students without substantial training in programming, who wish to generate and examine sound signals using a written script. In this article, the essence of AUX is discussed and practical examples of AUX scripts specifying various signals are illustrated. Additionally, two accompanying Windows-based programs and development libraries are described. AUX Viewer is a program that generates, visualizes, and plays sounds specified in AUX. AUX Viewer can also be used for class demonstrations or presentations. Another program, Psycon, allows a wide range of sound signals to be used as stimuli in common psychophysical testing paradigms, such as the adaptive procedure, the method of constant stimuli, and the method of adjustment. AUX Library is also provided, so that researchers can develop their own programs utilizing AUX. The philosophical basis of AUX is to separate signal generation from the user interface needed for experiments. AUX scripts are portable and reusable; they can be shared by other researchers, regardless of differences in actual AUX-based programs, and reused for future experiments. In short, the use of AUX can be potentially beneficial to all members of the research community-both those with programming backgrounds and those without.

  2. CEA technical-economic activity report - Year 2014

    International Nuclear Information System (INIS)

    2015-01-01

    This report presents an assessment of activities undertaken by the CEA in the field of energy technique and economy during 2014. Technical-economic studies aims at contributing to national orientations on energy, at R and D program orientations, at highlighting and strengthening synergies between nuclear technologies and new energy technologies, and at strengthening the credibility of these technologies. After a presentation of the organisation of technique and economy within the CEA, of the involved bodies and departments, of the addressed themes (photovoltaic, wind, biomass and biofuels, hydrogen-based systems, mobility, electric systems and grids), the report presents studies performed in relationship with the national energy strategy and with energy scenarios, studies performed in the nuclear field (on fourth-generation reactors, on the front-end and back-end of the fuel cycle), studies performed in the field of new energy technologies and climate (hydrogen and storage, biofuels, climate, mobility, solar, electric systems). The next part addresses academic aspects, methodological studies and modelling studies. Contributions and participations to conferences, and publications are indicated

  3. Radioiodination of monoclonal antibody intact anti-CEA

    International Nuclear Information System (INIS)

    Okada, H.; Souza, I.T.T.; Silva, C.P.G.

    1990-11-01

    The purpose of this study is to examine a convenient system that can be used to iodinate monoclonal antibodies which is rapid, simple, efficient and reproducible, and which can be accomplished in radiopharmaceutical laboratories. It is important to remember that antibodies are sensitive biochemicals, subject to losses of the activity that is essential to their mode of action, namely the ability to bind specific antigen. The advent of solid phase iodination agents has greatly expanded the range of gentle iodination techniques available for iodinating sensitive biological materials. The agent most widely used is the Iodogen (1,3,4,6 tetrachloro-3a-6a diphenylglycoluril) method. Anti-CEA 4C sub(11) IgG sub(2a,k) (prepared in the Ludwig Institute-Sao Paulo-Brazil ) is used as model to evaluate the Iodogen methodology. The miniature chromatographic system, also rapid, accurate, simple, efficient was elaborated to determine the labelling efficiency incorporation of iodine into immunoglobulin, and the radiochemical purity of sup(131)I-anti-CEA. (author)

  4. CEA contribution to power plant operation with high burnup level

    International Nuclear Information System (INIS)

    1981-03-01

    High level burnup in PWR leads to investigate again the choices carried out in the field of fuel management. French CEA has studied the economic importance of reshuffling technique, cycle length, discharge burnup, and non-operation period between two cycles. Power plants operators wish to work with increased length cycles of 18 months instead of 12. That leads to control problems because the core reactivity cannot be controlled with the only soluble boron: moderator temperature coefficient must be negative. With such cycles, it is necessary to use burnable poisons and for economic reasons with a low penalty in end of cycle. CEA has studied the use of Gd 2 O 3 mixed with fuel or with inert element like Al 2 O 3 . Parametric studies of specific weights, efficacities relatively to the fuel burnup and the fuel enrichment have been carried out. Particular studies of 1 month cycles with Gd 2 O 3 have shown the possibility to control power distribution with a very low reactivity penalty in EOC. In the same time, in the 100 MW PWR-CAP, control reactivity has been made with large use of gadolinia in parallel with soluble boron for the two first cycles

  5. 3rd CEAS Specialist Conference on Guidance, Navigation and Control

    CERN Document Server

    Drouin, Antoine; Roos, Clément

    2015-01-01

    The two first CEAS (Council of European Aerospace Societies) Specialist Conferences on Guidance, Navigation and Control (CEAS EuroGNC) were held in Munich, Germany in 2011 and in Delft, The Netherlands in 2013. ONERA The French Aerospace Lab, ISAE (Institut Supérieur de l’Aéronautique et de l’Espace) and ENAC (Ecole Nationale de l’Aviation Civile) accepted the challenge of jointly organizing the 3rd edition. The conference aims at promoting new advances in aerospace GNC theory and technologies for enhancing safety, survivability, efficiency, performance, autonomy and intelligence of aerospace systems. It represents a unique forum for communication and information exchange between specialists in the fields of GNC systems design and operation, including air traffic management. This book contains the forty best papers and gives an interesting snapshot of the latest advances over the following topics: l  Control theory, analysis, and design l  Novel navigation, estimation, and tracking methods l  Aircr...

  6. Histoire, histoires… Blood Upon the Rose de Gerry Hunt et Louis Riel. A Comic Strip Biography de Chester Brown

    Directory of Open Access Journals (Sweden)

    Valérie Morisson

    2011-10-01

    Full Text Available Dans deux bandes dessinées historiques abordant des épisodes centraux de l’histoire nationale irlandaise et manitobienne, Gerry Hunt et Chester Brown mettent en scène des héros devenus martyrs en leur pays. Leurs choix scénaristiques et graphiques sont très éloignés mais les deux auteurs se penchent sur l’exemplarité contestée des héros et revendiquent le droit de fournir aux lecteurs des points de vue audacieux sur les mythes fondateurs de la nation. La bande dessinée leur permet de s’affranchir d’une tradition historiographique nationaliste. Blood Upon the Rose et Louis Riel sont néanmoins sous-tendues par deux visions divergentes de l’histoire. La lutte pour l’indépendance est présentée soit comme le fait d’un individu soit comme un élan collectif.In their historical graphic novels, focused on pivotal episodes of Irish and Manitobian history, Gerry Hunt and Chester Brown put in the limelight two heroes that are, in their countries, elevated to the status of martyrs. If the authors’ graphic and narrative choices differ, both of them question the virtues of these much-debated heroes and claim their right to provide well-grounded but daring interpretations of the forging of the nation and its myths. Blood Upon the Rose and Chester Brown are nonetheless underpinned by two diverging visions of History since the fight for independence is viewed either as the achievement of an enlightened individual or as the result of a collective rebellion.

  7. Therapeutic Applications of Rose Hips from Different Rosa Species.

    Science.gov (United States)

    Mármol, Inés; Sánchez-de-Diego, Cristina; Jiménez-Moreno, Nerea; Ancín-Azpilicueta, Carmen; Rodríguez-Yoldi, María Jesús

    2017-05-25

    Rosa species, rose hips, are widespread wild plants that have been traditionally used as medicinal compounds for the treatment of a wide variety of diseases. The therapeutic potential of these plants is based on its antioxidant effects caused by or associated with its phytochemical composition, which includes ascorbic acid, phenolic compounds and healthy fatty acids among others. Over the last few years, medicinal interest in rose hips has increased as a consequence of recent research that has studied its potential application as a treatment for several diseases including skin disorders, hepatotoxicity, renal disturbances, diarrhoea, inflammatory disorders, arthritis, diabetes, hyperlipidaemia, obesity and cancer. In this review, the role of different species of Rosa in the prevention of treatment of various disorders related to oxidative stress, is examined, focusing on new therapeutic approaches from a molecular point of view.

  8. Chevilly Larue, L'Hay les Roses: twin geothermal plants

    International Nuclear Information System (INIS)

    Jeanson, E.

    1995-01-01

    The Chevilly Larue/L'Hay les Roses (Paris region, France) low energy geothermal plants are interconnected and thus represent the greatest geothermal heat network in Europe. The two plants are 2.5 km apart and supply 13000 collective lodgings in energy using a 60 km network with a 75 MW power. Gas or fuel auxiliary heating systems are used in winter to increase water temperature up to 105 C, but the part of energy released by geothermics remains of about 70 to 80%. The network will be extended in the next years to Fresnes and Villejuif neighbouring towns. In 1996, the SEMHACH company, which manage the two plants, will put into service a mixed electricity and heat production plant in L'Hay les Roses. (J.S.). 2 photos

  9. Partial preferential chromosome pairing is genotype dependent in tetraploid rose.

    Science.gov (United States)

    Bourke, Peter M; Arens, Paul; Voorrips, Roeland E; Esselink, G Danny; Koning-Boucoiran, Carole F S; Van't Westende, Wendy P C; Santos Leonardo, Tiago; Wissink, Patrick; Zheng, Chaozhi; van Geest, Geert; Visser, Richard G F; Krens, Frans A; Smulders, Marinus J M; Maliepaard, Chris

    2017-04-01

    It has long been recognised that polyploid species do not always neatly fall into the categories of auto- or allopolyploid, leading to the term 'segmental allopolyploid' to describe everything in between. The meiotic behaviour of such intermediate species is not fully understood, nor is there consensus as to how to model their inheritance patterns. In this study we used a tetraploid cut rose (Rosa hybrida) population, genotyped using the 68K WagRhSNP array, to construct an ultra-high-density linkage map of all homologous chromosomes using methods previously developed for autotetraploids. Using the predicted bivalent configurations in this population we quantified differences in pairing behaviour among and along homologous chromosomes, leading us to correct our estimates of recombination frequency to account for this behaviour. This resulted in the re-mapping of 25 695 SNP markers across all homologues of the seven rose chromosomes, tailored to the pairing behaviour of each chromosome in each parent. We confirmed the inferred differences in pairing behaviour among chromosomes by examining repulsion-phase linkage estimates, which also carry information about preferential pairing and recombination. Currently, the closest sequenced relative to rose is Fragaria vesca. Aligning the integrated ultra-dense rose map with the strawberry genome sequence provided a detailed picture of the synteny, confirming overall co-linearity but also revealing new genomic rearrangements. Our results suggest that pairing affinities may vary along chromosome arms, which broadens our current understanding of segmental allopolyploidy. © 2017 The Authors The Plant Journal published by John Wiley & Sons Ltd and Society for Experimental Biology.

  10. Preparation of Labelled I131 Rose-Bengal

    International Nuclear Information System (INIS)

    Mayani, Mbutyabo; Chabouri, Galaal.

    1978-01-01

    Rose bengal purified on a Sephadex G-25 column has been labelled with iodine-131. The exchange reaction has been undertaken in an ether - alcohol medium. The influence of different factors (iodine concentration, Psup(h), purity and chemical form of the substratum, reaction rate) on the labelling yield has been studied. Radiochemical yield of 90% have been obtained in some conditions instead of the normal 80% reported in the literature

  11. Mutation induction of roses through in vitro propagation

    International Nuclear Information System (INIS)

    Amran Abd Halim; Azhar Mohamad; Rusli Ibrahim

    2002-01-01

    The genus Rosa has been exploited for a variety used extensively in commercial production for many cultivars. Mutation induction is an alternative way of creating more variations in a single variety. Radiosensitivity test was carried out to identify optimum doses in mutation induction. Shoot tips of excises from in vitro plantlets were irradiated with doses of 0, 20, 40, 60, 80 and 100 Gy using a gamma cell with a 60 Co source at dose rate of 0.25 Gy s -1 . Irradiated shoot tips were cultured on semi solid modified Murashige and Skoog (MS) containing cytokinin (BAP) hormone and incubated at 24 with a photoperiod of 16 hours (3500 lux). Radiosensitivity was assessed by the rate of shoot proliferation four weeks after treatment. Increasing gamma ray doses caused a reduction of survival rate as well as the average shoots produced per plantlet. Through linear estimation of buds and shoots proliferation, radiation dose that reduced the growth to 50% of the control treatment (LD 50 ) was 53 Gy for miniature roses and 60 Gy for cut roses. Based on the radiosensitivity test 20 and 40 Gy were selected for irradiation to get new mutant varieties of roses. Changes in flower characters were found in three treated plants after three months in the green house. (Author)

  12. 75 FR 20778 - Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR

    Science.gov (United States)

    2010-04-21

    ...-AA87 Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR AGENCY: Coast... during the Portland Rose Festival Fleet Week from June 2, 2010, through June 7, 2010. The security zone... is a need to provide a security zone for the 2010 Portland Rose Festival Fleet Week, and there is...

  13. 76 FR 60447 - Florigene Pty., Ltd.; Determination of Nonregulated Status for Altered Color Roses

    Science.gov (United States)

    2011-09-29

    ... Nonregulated Status for Altered Color Roses AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We are advising the public of our determination that two hybrid rose lines developed by..., seeking a determination of nonregulated status for two hybrid rose lines designated as IFD-524[Oslash]1-4...

  14. 77 FR 61426 - Rose Atoll National Wildlife Refuge, American Samoa; Draft Comprehensive Conservation Plan and...

    Science.gov (United States)

    2012-10-09

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R1-R-2012-N171; 1265-0000-10137-S3] Rose... Rose Atoll National Wildlife Refuge (NWR/refuge) for public review and comment. In the Draft CCP/EA, [email protected] . Include ``Rose Atoll National Wildlife Refuge Draft CCP/EA'' in the subject line of the...

  15. 77 FR 15263 - Security Zone; Portland Rose Festival on Willamette River; Portland, OR

    Science.gov (United States)

    2012-03-15

    ... Zone; Portland Rose Festival on Willamette River; Portland, OR AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast Guard will enforce the Portland Rose Festival... Willamette River during the Portland Rose festival. During the enforcement period, no person or vessel may...

  16. 76 FR 28315 - Security Zone; Portland Rose Festival on Willamette River

    Science.gov (United States)

    2011-05-17

    ... Zone; Portland Rose Festival on Willamette River AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast Guard will enforce the Portland Rose Festival Security Zone in... River during the Portland Rose festival. During the enforcement period, no person or vessel may enter or...

  17. Development of polyclonal and monoclonal antibodies to Rose rosette virus nucleoprotein

    Science.gov (United States)

    Garden roses, which form the cornerstone of the multi-billion dollar landscape industry, annually generate wholesale US domestic production valued at ca. $400 million. Over the past few decades Rose rosette disease, caused by Rose rosette virus (RRV; genus Emaravirus), has become a major threat to t...

  18. Control of effluents and environmental surveillance of the CEA centres. 1997 status; Controle des rejets et surveillance de l'environnement des centres CEA. Bilan 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The environmental quality in the vicinity of CEA facilities is a major concern of the safety policy of the CEA. The aim of this document is to inform the public about the gaseous and liquids radioactive effluents released by the CEA centres under the permission of the ministry. It provides a status of the effluents and of the radioactivity levels measured near the CEA centres in 1997, using air, water, vegetation and milk samples. A comparison is made with the measurements performed during the 1993-1996 period. The data presented comes from the regulatory registers transmitted to the agency for the protection against ionizing radiations (OPRI) which belongs to the ministry of health. (J.S.)

  19. Hearing of Mr Bernard Bigot, general administrator of the Atomic Energy Commissariat (CEA), on the CEA missions and on Cadarache events

    International Nuclear Information System (INIS)

    2009-01-01

    In this hearing by the Sustainable Development and Land Planning Commission of the French National Assembly, the role and missions of the CEA are presented while evoking its relationship with the State. The CEA representative evokes the various research activities in three main domains: energy, defence, information and health technologies. Then, he discusses the problem of the ageing and dismantling of some installations, notably in the plutonium Technology workshop (ATPu) in Cadarache. He describes this installation, the processes in which it is involved, the safety and security requirements, and comments the problem which occurred in this workshop (plutonium retention in glove boxes). Then he answers several questions asked by the Commission members about the way the CEA handled this incident, and about its severity. Other aspects are addressed like the importance of the nuclear industry and the role the CEA could have in the management of renewable energies at the national level

  20. Scientific evaluation at the French Atomic Energy Commission (CEA). 2005-2006 annual report; L'evaluation scientifique au CEA. Rapport annuel 2005-2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This report aims at presenting the scientific evaluation activities carried out at the CEA during the years 2005-2006. The evaluation system is described in detail. It comprises two aspects: the evaluation of the scientific policy implemented by the scientific Council and by the visiting committee of the CEA, and the evaluation of the laboratories, performed by a pool of 36 scientific councils. The evaluation by external and independent parties is the key point of this system. This document makes a status of the evaluations performed in 2005 and 2006. It presents a synthesis of the conclusions of the evaluation authorities. The actions implemented by the CEA to take into consideration the recommendations are also reported with the improvements noticed. The two topics examined by the scientific Committee and by the visiting committee were dealing with the energy domain, which is a strategic issue for the CEA. The examination of the researches on future nuclear reactors and on new energy technologies have shown the major role played by the CEA in the recent advances in these domains. About 95% of the laboratories activity was examined during the 2002-2005 period. The richness of the remarks and recommendations made by the scientific councils should allow the CEA to improve the quality and relevance of its research works. The start-up of the 2006-2009 evaluation cycle has been the occasion to modify the evaluation of some research domains in order to take into account the evolution of programs. The evaluation system of the CEA is highly consistent with the AERES principles. Its implementation, adapted to each type of activity (fundamental research, applied research, technological developments) allows the CEA to follow up a permanent improvement approach. (J.S.)

  1. 15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).

    Science.gov (United States)

    2010-01-01

    ...) The following are examples of CEAS projects and services: (1) CEAS prepares data-based studies and... experiment design, data analysis, and data management support to project managers and produces merged... global oceanographic data base from observations taken during the First GARP Global Experiment (FGGE). (b...

  2. Aeroacoustics research in Europe : the CEAS-ASC report on 1997 highlights

    NARCIS (Netherlands)

    Rienstra, S.W.

    1998-01-01

    This paper is a report on the highlights of aeroacoustics research and development in Europe in 1997, compiled from information provided in the CEAS Aeroacoustics Specialists Committee (ASC). The Confederation of European Aerospace Societies (CEAS) comprises the national Aerospace Societies of

  3. Tumor, serum and urine carcinoembryonic antigen (CEA) in upper urinary tract urothelial cancer

    International Nuclear Information System (INIS)

    Stefanovic, V.; Ignjatovic, M.

    1987-01-01

    The aim of this investigation was to study the possible diagnostic value of a CEA test in cancer of the renal pelvis and ureter. Thirty-eight patients with upper urinary tract cancer, 15 patients with transitional cell carcinoma of the bladder, 6 kidney carcinoma patients and 25 healthy adults were studied. CEA was determined in tumor tissue, serum and urine, by using a monoclonal radioimmunoassay. Increased serum CEA level was found in 7 out of 27 patients (26%) with active cancer of the renal pelvis and ureter. None of 11 patients with inactive cancer had an increased serum CEA level. No significant correlation was found between the serum CEA level and the histological grading. The tumor CEA content varied markedly, from values obtainted in normal urothelium up to 840 ng/g wet weight. CEA content of tumor tissue did not correlate with the serum level. Our data suggest that serum and urine CEA have not diagnostic accuracy for clinical diagnosis of upper tract urothelial cancer. (orig.) [de

  4. Application for Approval : White Rose Canada-Newfoundland Benefits Plan and White Rose Development Plan : Decision 2001.01

    International Nuclear Information System (INIS)

    Stanley, H.H.

    2001-01-01

    The White Rose offshore oil development project is located in the Jeanne d'Arc Basin 350 km east of Newfoundland. It is a co-venture between Husky Oil Operations Ltd. and Petro-Canada. The project is expected to recover 230 million barrels of oil over a 12 year period. This report explains the decision of the Canada-Newfoundland Offshore Petroleum Board regarding the application by Husky Oil and its partner for approval of its plans for the development of the White Rose oil field. The White Rose Development Plan describes the proponent's interpretation of the geology and reservoir characteristics of the oil field and provides estimates of hydrocarbon reserves. The drilling approach that the proponents plan to use at their facilities were also described along with the environmental parameters of the facilities. The Board's responsibility is to ensure that hydrocarbons are produced in accordance with good oil field practice including efficient recovery, prevention of waste and safe operational practices. The White Rose Canada-Newfoundland Benefits Plan addresses issues in the areas that will benefit the province, including: an East Coast Regional Office in St. John's, Newfoundland; employment; research and development; goods and services; disadvantaged individuals and groups; and monitoring and reporting. In terms of protection of the environment, the Board makes its assessment under the guidance of the Canadian Environmental Assessment Act which deals with issues such as the effects of routine releases of greenhouse gas emissions, drilling discharges, production discharges and accidental discharges. It also sets rules for decommissioning and abandonment of floating production, storage and off loading vessels and underwater facilities. The Board considered the application and has decided to approve the Benefits Plan, subject to certain conditions described in this report. tabs., figs., appendices

  5. Advanced uncooled infrared focal plane development at CEA/LETI

    Science.gov (United States)

    Tissot, Jean-Luc; Mottin, Eric; Martin, Jean-Luc; Yon, Jean-Jacques; Vilain, Michel

    2017-11-01

    LETI/LIR has been involved for a few year in the field of uncooled detectors and has chosen amorphous silicon for its microbolometer technology development. Uncooled IR detectors pave the way to reduced weight systems aboard satellites. The silicon compatibility of our thermometer is a key parameter which has enabled a very fast technology development and transfer to industry. This competitive technology is now able to provide a new approach for IR detectors for space applications. This paper presents the main characteristics of the CEA / LETI technology which is based on a monolithically integrated structure over a fully completed readout circuit from a commercially available 0.5 μm design rules CMOS line. The technology maturity will be illustrated by the results obtained at LETI/LIR and SOFRADIR on a 320 x 240 with a pitch of 45 μm. First improvement on device reliability and characterization results will be presented.

  6. The development of lasers at the CEA Military Applications Direction

    International Nuclear Information System (INIS)

    Coutant, J.

    1997-01-01

    A historical review of the development of lasers and their application at the CEA to the study of plasma inertial confinement in the framework of military applications, is presented. The first solid laser was a ruby laser, and has been used for studying laser-matter interaction, which led to a better knowledge of fusion plasmas. Advancements were achieved with a new lasing medium (neodymium doped glass), the control of pulse duration and shape, parallel setting of several laser chains (OCTAL), the use of glass disks instead of bars (PHEBUS laser)... In the late 70's, power lasers reached the power needed to experiment D-T implosions and give the way to future simulations of the plasma conditions encountered in thermonuclear explosions

  7. Report on transparency and nuclear safety 2014 - Cadarache CEA centre

    International Nuclear Information System (INIS)

    2015-07-01

    This document proposes, first, a presentation of the Cadarache CEA centre, of its activities and installations, gives a rather detailed overview of measures related to safety and to radiation protection within these activities and installations. Then it reports significant events related to safety and to radiation protection which occurred in 2014 and have been declared to the ASN. Next, it discusses the results of release measurements (liquid and gaseous effluents, radiological assessment, and chemical assessment for various installations) and the control of the chemical and radiological impact of these gaseous and liquid effluents on the environment. Finally, it addresses the issue of radioactive wastes which are stored in the different nuclear base installations of the Centre, indicates the different measures aimed at limiting the volume of these warehoused wastes and addresses their impact on health and on the environment. Nature and quantities of warehoused wastes are specified. Remarks and recommendations of the CHSCT are given

  8. The stationary storage of energy. Available technologies and CEA researches

    International Nuclear Information System (INIS)

    2012-01-01

    After a discussion of the main challenges related to the stationary storage of energy, this publication proposes an overview of the different available technologies: plant for transfer of energy by pumping, compressed air, energy flywheels, hydrogen, lithium-ion battery, redox-flow battery, thermal storage by sensitive heat, thermal-chemical storage coupled to a thermal solar system, thermal storage by phase change, superconductive inductance storage, super-capacitors. It discusses the criteria of choice of storage technology, either for electric energy storage or for heat storage. It proposes an overview of researches performed within the CEA on storage systems: electrochemical, thermal, and hydrogen-based storages. The final chapter addresses current fundamental researches on storage in the field of lithium-ion batteries, hydrogen as a fuel, and thermoelectricity

  9. Recent advances in ignition target physics at CEA

    International Nuclear Information System (INIS)

    Tassart, J.

    2003-01-01

    The objective of the Ignition Physics Program at CEA is to burn DT capsules on the Laser Mega Joule (LMJ) at the beginning of the next decade. Recent progress on Laser Plasma Interaction, hohlraum energetics, symmetry, ablator physics and hydrodynamic instabilities allow to remove most of these latter, to precise laser and target specifications and to elaborate a strategy toward ignition. These studies include theoretical work, numerical simulations, diagnostics developments and experiments partly done in collaboration with the US DOE. Construction of facilities is ongoing: LMJ beam prototype is planed to fire 7 kJ at the center of the target chamber at 0.35 mm at the end of 2002 and the LMJ (a 240 beams 1.8 MJ laser) is planned to be ready for experiments at the end of 2009. (author)

  10. Recent advances in indirect drive ICF target physics at CEA

    International Nuclear Information System (INIS)

    Tassart, J.

    2001-01-01

    The objective of Target Physics Program at CEA is the achievement of ignition on the LMJ, a glass laser facility of 1.8 MJ which will be completed by 2008. It is composed of theoretical work, experimental work and numerical simulations. An important part of experimental studies is made in collaboration with U.S. DOE Laboratories: Lawrence Livermore National Laboratory, Los Alamos National Laboratory and the Laboratory for Laser Energetics at the University of Rochester. Experiments were performed on Phebus, NOVA (LLNL) and OMEGA (LLE) ; they included diagnostics developments. Recent efforts have been focused on Laser Plasma Interaction, hohlraum energetics, symmetry, ablator physics and hydrodynamic instabilities. Ongoing work prepare the first experiments on the LIL which is a prototype facility of the LMJ (8 of its 240 beams). They will be performed by 2002. Recent progress in ICF target physics allows us to precise laser specifications to achieve ignition with reasonable margin. (author)

  11. Development of radiolabelling techniques of anti-CEA monoclonal antibody

    International Nuclear Information System (INIS)

    Castiglia, S.G. de

    1998-01-01

    The purpose of this work was to label monoclonal and polyclonal antibodies with 99 Tc m such as the ior-CEA-1 antibody and polyclonal IgG using a direct method, to check the radiochemical and biological behavior of labelled products, to prepare it under sterile and apyrogenic conditions as a lyophilized kit and to employ it in clinical trials. In addition, a photoactivation method was used to label polyclonal IgG with 99 Tc m and to compare with the established method using mercaptoethanol (2-ME) as the reducing agent. Finally polyclonal IgG was labelled using an indirect method in which a chelator was covalently attached to the protein and the 99 Tc m added as glucoheptonate complex. The properties of 99 Tc m when labelled with monoclonal and polyclonal antibodies by different methods were assessed by in vitro and in vivo studies

  12. Recapitulative list of the C.E.A. reports published by the French Atomic Energy Commission (n.757-1062, december 1957-december 1958) supplement to C.E.A. reports n. 593 and 756

    International Nuclear Information System (INIS)

    Schmiterlow, C.G.; Cohen, Y.

    1958-01-01

    Recapitulative list of the C.E.A. reports published by the French Atomic Energy Commission. (number 757-1062, december 1957 - december 1958). Supplement to C.E.A. reports number 593 and 756. (author) [fr

  13. 11 juillet 2014 - Y. Bréchet Haut-Commissaire à l’énergie atomique et aux énergies alternatives (CEA) en France

    CERN Multimedia

    Barnard, Henry

    2014-01-01

    Monsieur Yves Bréchet en visite dans le tunnel du LHC au Point 5 ainsi que la caverne expérimentale de CMS avec T. Camporesi, Porte-parole de la Collaboration CMS. Signature du livre d'or avec F. Bordry, Directeur des accélérateurs et de la technologie.

  14. Clinical significance of determination of serum VEGF and CEA levels in patients with colorectal cancer

    International Nuclear Information System (INIS)

    Du Xiaohui; Song Shaobai; Zheng Wei

    2007-01-01

    Objective: To study the applicability of combined determination of serum VEGF and CEA levels in the diagnosis of colorectal cancer as well as the relationship between VEGF level and stage of the disease. Methods: Serum VEGF (with ELISA) and CEA (with RIA) levels serum were detected in 28 patients with colorectal cancer of various stages and 29 controls. Results: The diagnostic positive rate was 53.6% (15/28), 39.3% (11/28), 71.4% (20/28) with CEA, VEGF and combined test for colorectal cancer, respectively. The serum VEGF levels in patients with advance colorectal cancer were significantly higher than those in patients with earlier stages diseases and controls, VEGF levels were positively correlated with CEA levels (P<0.05). Conclusion: Combined detection of the levels of serum VEGF and CEA could improve significantly the diagnostic positive rate in patients with colorectal cancer. (authors)

  15. Disposal of the radioactive effluents at the 'Commissariat a l'Energie Atomique'. Treatment leading to evacuation into a river; Probleme du rejet des residus radioactifs liquides au CEA. Traitements aboutissant a des rejets en riviere

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel; Menoux; Candillon [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    to find out in loaded water, 10) Impot elements other than Sr{sup 90} are also studied. (author) [French] Le probleme du traitement des residus radioactifs liquides au CEA est envisage sous l'angle du rejet ultime en riviere dans des conditions optima permettant de satisfaire aux Normes de la protection. 2) A Saclay, ou l'on ne dispose que d'un etang ou l'eau ne se renouvelle pas, les liquides epures sont envoyes par camion citerne a Fontenay-aux-Roses, ou ils sont deverses provisoirement - dans les egouts - en attendant qu'un point de rejet en Seine ait ete determine. 3) Au Bouchet, les eaux residuaires de l'Usine de traitement de minerais d'urano-thorianite devront etre traitees en deux temps de facon a separer le radium dans une premiere phase, ce qui facilitera l'epuration au cours de la deuxieme phase. 4) En vue des futurs rejets a Marcoule, une etude a ete conduite a Saclay, sur des effluents synthetiques - type Marcoule - ayant pour but de mettre au point des procedes d'elimination selective du Sr d'une part, du Cs d'autre part, par coprecipitation. 5) Dans le cas general du rejet ultime en riviere, les problemes suivants sont successivement envisages: - predilution entre les bassins de stockage des eaux epurees et le fleuve; - mode d'injection dans le fleuve; - dilution dans le fleuve (etude prealable par traceurs); - evolution de l'activite dans les eaux du fleuve (adsorption par les organismes inertes ou vivants, contamination des berges); - incidence sur le choix d'un site; - dilution isotopique. 6) Ce dernier probleme est specialement detaille. 7) La teneur de l'eau en un element donne conditionne la dilution isotopique de son isotope radioactif. L'analyse decelant une carence, il est possible d'y suppleer par des rejets d'isotope stable. 8) Cette methode conduit en certains cas a des analyses delicates (en particulier dans le cas du {sup 90}Sr), la teneur en isotope

  16. Synthesis of mesoscale, crumpled, reduced graphene oxide roses by water-in-oil emulsion approach

    Science.gov (United States)

    Sharma, Shruti; Pham, Viet H.; Boscoboinik, Jorge A.; Camino, Fernando; Dickerson, James H.; Tannenbaum, Rina

    2018-05-01

    Mesoscale crumpled graphene oxide roses (GO roses) were synthesized by using colloidal graphene oxide (GO) variants as precursors for a hybrid emulsification-rapid evaporation approach. This process produced rose-like, spherical, reduced mesostructures of colloidal GO sheets, with corrugated surfaces and particle sizes tunable in the range of ∼800 nm to 15 μm. Excellent reproducibility for particle size distribution is shown for each selected speed of homogenizer rotor among different sample batches. The morphology and chemical structure of these produced GO roses was investigated using electron microscopy and spectroscopy techniques. The proposed synthesis route provides control over particle size, morphology and chemical properties of the synthesized GO roses.

  17. Sensibilisation aux gestes et postures de travail - French version only

    CERN Multimedia

    2004-01-01

    Nous vous proposons un nouveau cours de sécurité lié aux manutentions manuelles (durée 1 jour) : Sensibilisation aux gestes et postures de travail. Si vous êtes amené à manipuler régulièrement des charges lourdes ou volumineuses, cette formation peut vous aider à prévenir les lésions musculaires ou dorsales. A l'issue de cette formation, vous serez capable d'adopter et d'appliquer les principes de base de sécurité physique et d'économie d'efforts dans les manipulations d'objets. Les cours sont pris en charge par la Commission de Sécurité. L'inscription EDH est obligatoire. Pour plus d'information, veuillez consulter les pages Formation & Développement (Groupe Sécurité)

  18. Therapeutic efficacy of rose oil: A comprehensive review of clinical evidence

    Directory of Open Access Journals (Sweden)

    Safieh Mohebitabar

    2017-04-01

    Full Text Available Objective: Rose oil is obtained from the petals of difference Rosa species especially Rosa centifolia L. and Rosa damascena Mill. Various pharmacological properties have been attributed to rose oil. The aim of the present study was to review the rose oil therapeutic effects which had been clinically evaluated in trial studies. Materials and Methods: Google scholar, PubMed, Cochrane Library, and Scopus were searched for human studies which have evaluated the therapeutic effects of rose oil and published in English language until August 2015. Results: Thirteen clinical trials (772 participants were included in this review. Rose oil was administered via inhalation or used topically. Most of the studies (five trials evaluated the analgesic effect of rose oil. Five studies evaluated the physiological relaxation effect of rose oil. Anti-depressant, psychological relaxation, improving sexual dysfunction, and anti-anxiety effects were the other clinical properties reported for rose oil. Conclusion: Numerous studies on the pharmacological properties of rose oil have been done in animals, but studies in humans are few.  In this study, it was observed that rose oil had physiological and psychological relaxation, analgesic and anti-anxiety effects. To obtain conclusive results on the efficacy and safety of rose oil, further clinical trials with larger sample size and better designation are required.

  19. La recherche-action participative facilite l'adaptation aux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ces travaux comprenaient un riche portefeuille de recherches sur l'adaptation aux changements climatiques dans le secteur de l'agriculture. La méthodologie privilégiée dans le cadre du programme, la recherche-action participative, s'est avérée fructueuse et a permis de mettre au point et de déployer des solutions ...

  20. Accroissement du recours aux politiques fiscales dans la lutte ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Incidence de la hausse des taxes sur le tabac et du prix des produits du tabac en Ukraine, en Russie et au Bélarus. La recherche destinée aux responsables des politiques de l'Ukraine, de la Russie et du Bélarus mettra en évidence la façon dont les mesures de taxation des produits du tabac peuvent contribuer.

  1. Foire aux questions: Bourse de recherche 2018 du CRDI | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Vous remarquerez que d'importantes modifications ont été apportées aux critères d'admissibilité dans les deux dernières années. 2) Je suis étudiant à la maîtrise. Suis-je admissible à une bourse de recherche ? En principe oui. Toutefois, il est important de lire les spécifications du programme qui vous intéresse, car les ...

  2. Aspects Phenotypiques De La Resistance Aux Β- Lactamines Des ...

    African Journals Online (AJOL)

    Conclusion: L'identification des phénotypes de résistance de P.aeruginosa par la technique d'antibiogramme en milieu gélosé constitue une alternative pour les laboratoires de bactériologie médicale dans les pays aux ressources limitées comme le Togo, où les techniques de biologie moléculaire ne sont pas disponibles ...

  3. Adaptation aux changements climatiques des bassins versants en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les résultats de recherche seront diffusés dans des publications scientifiques à comité de lecture, dans le cadre d'une interaction critique avec la sphère des politiques, ainsi qu'à l'occasion d'un institut d'été destiné aux chercheurs et ... The Trustees of Ashoka Trust for Research in Ecology and the Environment (ATREE).

  4. CRDI foire aux questions | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1. Quels sont les éléments importants à mentionner dans ma demande d'emploi ? Il importe de démontrer, au moyen d'exemples concrets, de quelle façon vos qualifications correspondent aux exigences du poste en ce qui concerne les études, l'expérience et la langue. 2. Comment saurai-je si ma demande d'emploi a bel ...

  5. Aquaculture intérieure et adaptation aux changements climatiques ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce projet porte sur l'élevage du tilapia dans de petits étangs fermiers ou des cages flottantes dans les rivières et les réservoirs du nord de la Thaïlande. Les chercheurs exploreront des façons d'adapter les pratiques aquacoles aux changements climatiques et analyseront la valeur de l'aquaculture comme stratégie ...

  6. Adapter l'information climatique aux besoins des utilisateurs | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    29 mars 2011 ... Cet exposé politique résume les leçons tirées du forum d'apprentissage du programme ACCA entitulé " Faciliter l'accès aux prévisions météorologiques saisonnières et savoir mieux les exploiter" qui a pris lieux à Nairobi, Kenya en mars 1010.

  7. Substrates and irrigation levels for growing desert rose in pots

    Directory of Open Access Journals (Sweden)

    Ronan Carlos Colombo

    Full Text Available ABSTRACT In the past decades, desert rose has become a very popular ornamental plant, especially among collectors, due to its exotic and sculptural forms. However, it has been grown on a commercial scale only recently, and little is known about how to best manage it as a container-grown plant, or even which potting medium (substrate to recommend. Therefore, the aim of this study was to investigate the interactions between potting media and irrigation levels for growing desert rose as a potted ornamental plant. The experiment was conducted in a greenhouse using a 6 x 2 factorial arrangement with six replications, six potting media and two irrigation levels. The mixes were characterized by measuring their physical properties, specifically the density and water retention capacity (WRC, as well as chemical properties, such as the pH and electrical conductivity (EC. After 210 days, plant growth and plant water consumption were evaluated and measured. A lower dry density for the vermiculite mixes was observed in comparison to that for the sand mixes. However, WRC ranged from 428 to 528 mL L-1 among the mixes, values considered close to ideal. In general, plant growth exhibited higher increases in mixes consisting of coconut fiber + sand or vermiculite, regardless of the irrigation level. Mixes of vermiculite + coconut fiber and sand + coconut fiber can be used to grow desert rose in pots, as long as irrigation is used to maintain the moisture content of the potting medium (mix between 60-70% and 80-90% of the WRC.

  8. Strengthening Software Authentication with the ROSE Software Suite

    International Nuclear Information System (INIS)

    White, G

    2006-01-01

    Many recent nonproliferation and arms control software projects include a software authentication regime. These include U.S. Government-sponsored projects both in the United States and in the Russian Federation (RF). This trend toward requiring software authentication is only accelerating. Demonstrating assurance that software performs as expected without hidden ''backdoors'' is crucial to a project's success. In this context, ''authentication'' is defined as determining that a software package performs only its intended purpose and performs said purpose correctly and reliably over the planned duration of an agreement. In addition to visual inspections by knowledgeable computer scientists, automated tools are needed to highlight suspicious code constructs, both to aid visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary and not extensible. An open-source, extensible tool can be customized to the unique needs of each project (projects can have both common and custom rules to detect flaws and security holes). Any such extensible tool has to be based on a complete language compiler. ROSE is precisely such a compiler infrastructure developed within the Department of Energy (DOE) and targeted at the optimization of scientific applications and user-defined libraries within large-scale applications (typically applications of a million lines of code). ROSE is a robust, source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C and C++ (handling the full C, C99, C++ languages and with current collaborations to support Fortran90). We propose to extend ROSE to address a number of security-specific requirements, and apply it to software authentication for nonproliferation and arms control projects

  9. Critical study of some soft-tissue equivalent material. Sensitivity to neutrons of 1 keV to 14 MeV; Etude critique de quelques materiaux equivalents aux tissus mous. Sensibilite aux neutrons de 1 keV a 14 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Kerviler, H de; Pages, L; Tardy-Joubert, Ph [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    Authors have studied the elastic and inelastic reactions on various elements contribution to kerma in standard soft tissue and as a function of neutron energy from 1 keV to 14 MeV the ratio of kerma in tissue equivalent material to kerma in soft tissue. The results of calculations are made for materials without hydrogen in view to state exactly their neutron sensitivity and for the following hydrogenous materials: Rossi and Failla plastic, MixD, pure polyethylene and a new CEA tissue equivalent (a magnesium fluoride and polyethylene compound). Results for {gamma}-rays are given. (authors) [French] Les auteurs ont etudie la contribution au kerma total des reactions elastiques et inelastiques sur les divers composants du tissu mou standard et la variation, en fonction de l'energie des neutrons de 1 keV a 14 MeV, du rapport des kermas dans differents materiaux equivalents au tissu au kerma dans les tissus mous. Les materiaux etudies sont des materiaux sans hydrogene afin de preciser leur sensibilite aux neutrons et les materiaux hydrogenes suivants: plastique de Rossi et Failla, polyethylene pur, MixD, nouveau plastique CEA a base de polyethylene et de fluorure de magnesium. Les resultats pour les photons sont egalement rappeles. (auteurs)

  10. Clinical Significance of Plasma CEA Levels in the Patients with Cervical Carcinoma during Follow-Up

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Sung Beom; Kim, Joo Young; Choi, Myung Sun; Rha, Joong Yeol; Lee, Min Jae [Korea University College of Medicine, Seoul (Korea, Republic of)

    1991-12-15

    Carcinoembryonic antigen (CEA) has been studied in the field of gynecologic malignancy to determine whether it can be used as a tumor marker for early detection of recurrence or evaluation of therapeutic results. From January 1985 through December 1989, a total of 239 cervical cancer patients were entered for an analysis of plasma CEA level in the group with cervical cancer compared to the control group consisting of 65 normal healthy women and 18 women with benign gynecologic disease. Plasma CEA levels appear to be directly related with the tumor extension and as stages advance, the incidence of patients with abnormal plasma CEA levels is increased. Also, there seems to be a little higher incidence of abnormal CEA levels in patients with adenocarcinomas or adenosquamous carcinoma but not statistically significant because of small number of patients. When the patients developed recurrence, plasma CEA levels are markedly elevated in the majority, particularly in patients with hepatic metastases. In conclusion, serial plasma CEA checks could be used to detect recurrence during follow-up after treatment of cervical cancer.

  11. Clinical investigation of serum CEA in 120 patients with colorectal cancer

    International Nuclear Information System (INIS)

    Li Yusheng; Yang Liting; Yu Yunyun; Yu Suqing; Ma Shuqin

    2003-01-01

    To investigate the correlation between serum CEA and colorectal cancer, the pre-and postoperative serum CEA in 120 patients with colorectal cancer was measured by RIA, with other 24 cases of healthy donors as control. The results showed that serum CEA in control group and patient group were 9.84±2.44 ng/mL, 38, 85±19.21 ng/mL respectively, while colonic cancer group 37.43±18.58 ng/mL, rectal cancer group 39.72±20.67 ng/mL. There was significant difference between patient group and control group (P 0.05). Serum CEA of 37 among 44 cases with positive CEA findings decreased to 11.21±3.65 ng/mL during two months follow-up post-operation, whereas 50.63±24.38 ng/mL in 7/44 cases undergoing non-radical operation. The serum CEA of 41 recurrence cases was 43.12±17.15 ng/mL at six-year post-operation, with 87.80% of three-year recurrence rate. It suggested that the serum CEA test is a convenient method for colorectal cancer to preoperatively diagnose it, evaluate postoperative curative effect and detect tumor recurrence and metastasis

  12. A study of factors influencing plasma CEA levels in an unselected population.

    Science.gov (United States)

    Herbeth, B; Bagrel, A

    1980-01-01

    Plasma carcinoembryonic antigen (CEA) levels were measured by an immunoenzymic method (Abbott) in 1020 subjects attending the Preventive Medicine Centre (Vandoeuvre-les-Nancy). The results are assessed in relation to: sex, age, body build, fasting/normal food intake, smoking, alcohol intake, drug medication, and working environment. The mean plasma CEA level is 1.53 ng/ml. 87% of the total group has levels less than 2.5 ng/ml, 11.2% levels between 2.5 ng/ml and 5 ng/ml and 1.8% levels above 5 ng/ml. One person had a level above 10 ng/ml. Men had significantly higher CEA levels than women. Smoking was more frequent in both men and women with CEA levels above 2.5 ng/ml. Only in men were age, alcohol consumption and a poor work environment significantly associated with CEA levels higher than 2.5 ng/ml. Obesity in women was related to higher CEA levels. Food intake and drug medication were without influence on the CEA level.

  13. CA 19-9 as a marker in addition to CEA to monitor colorectal cancer.

    Science.gov (United States)

    Stiksma, Jolanda; Grootendorst, Diana C; van der Linden, Peter Willem G

    2014-12-01

    Carcinoembryonic antigen is the commonly used tumor marker in patients with colorectal cancer, and CA 19-9 might be an additional marker. The aim of this retrospective study was to investigate whether CA 19-9 levels can be used to monitor the disease process in patients with colorectal cancer who had no elevated CEA levels. The secondary aim was to determine if preoperative increased levels of CEA and CA 19-9 were associated with mortality. Two sets of data from patients with histologically confirmed colorectal cancer, were included in a single-center study. First, patients with a minimum of 3 serial measurements of CA 19-9 and CEA tumor markers were related to the clinical course of their disease. Second, patients with preoperative levels of CEA and CA 19-9 were related to survival. In patients with colorectal cancer and 3 serial measurements of tumor markers, 7.3% had only increased CA 19-9 levels without increased CEA levels, and 55.4% of the patients had an increase of CA 19-9 and CEA levels. In the patients with available preoperative markers, patients with only an increase of CA 19-9 had a significantly decreased 5-year survival compared with patients with an increase of only CEA (P = .013). CA 19-9 can be used as additional marker to follow the disease process in patients with colorectal cancer without an increase in CEA level. Patients with preoperative increased CA 19-9 level had a poorer 5-year survival than patients with preoperative increased CEA levels. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Origin of the color of Cv. rhapsody in blue rose and some other so-called "blue" roses.

    Science.gov (United States)

    Gonnet, Jean-François

    2003-08-13

    Flowers of the rose cultivar Rhapsody in Blue display unusual colors, changing as they age, from a vivid red-purple to a lighter and duller purple, which are based on tonalities corresponding to hue angles between 340 and 320 degrees in the CIELAB scale. Unexpectedly, the chemical basis of these colors is among the simplest, featuring cyanin (cyanidin 3,5-di-O-glucoside), the most frequent anthocyanin in flowers, as the sole pigment and quercetin kaempferol glycosides as copigments at a relatively low copigment/pigment ratio (about 3/1), which usually produces magenta or red shades in roses. This color shift to bluer shades is coupled with the progressive accumulation of cyanin into vacuolar anthocyanic inclusions (AVIs), the occurrence of which increases as the petals grow older. In addition to the normal lambda(max) of cyanin at approximately 545 nm, the transmission spectra of live petals and of epidermal cells exhibit a second lambda(max) in the 620-625 nm range, the relative importance increasing with the presence of AVIs. In petals of fully opened flowers, the only pigmented structures in the vacuoles of epidermal cells are AVIs; their intense and massive absorption in the 520-640 nm area produces a much darker and bluer color than measured for the vacuolar solution present at the very first opening stage. Cyanin is probably "trapped" into AVIs at higher concentrations than would be possible in a vacuolar solution and in quinonoidal form, appearing purple-blue because of additional absorption in the 580-630 nm area. Quite similar pigmentation features were found in very ancient rose cultivars (cv. L'Evêque or Bleu Magenta), also displaying this type of so-called "blue" color.

  15. Fusion technology. Annual report of the. Association Cea/EURATOM; Technologie de fusion.Rapport annuel de l`association CEA/Euratom

    Energy Technology Data Exchange (ETDEWEB)

    Magaud, P; Le Vagueres, F

    1997-12-31

    In 1996, the French EURATOM-CEA Association made significant contributions to the European technology programme. This work is compiled in this report as follows: the ITER CEA activities and related developments are described in the first section; blankets and material developments for DEMO, long term safety studies are summarised in the second part; the Underlying Technology activities are compiled in the third part of this report. In each section, the tasks are sorted out to respect the European presentation. For an easy reading, appendix 4 gives the list of tasks in alphabetical order with a page reference list. The CEA is in charge of the French Technology programme. Three specific organizational directions of the CEA, located on four sites (see appendix 5) are involves in this programme: Advanced Technologies Direction (DTA), for Material task; Nuclear Reactors Direction (DRN), for Blanket design, Neutronic problems, Safety tasks; Physical Sciences Direction (DSM) uses the competence of the Tore Supra team in the Magnet design and plasma Facing Component field. The CEA programme is completed by collaborations with Technicatome, COMEX-Nucleaire and Ecole Polytechnique. The breakdown of the programme by Directions is presented in figure 1. The allocation of tasks is given in appendix 2 and in appendix 3, the related publications. (author).

  16. Fusion technology. Annual report of the. Association Cea/EURATOM; Technologie de fusion.Rapport annuel de l`association CEA/Euratom

    Energy Technology Data Exchange (ETDEWEB)

    Magaud, P.; Le Vagueres, F.

    1996-12-31

    In 1996, the French EURATOM-CEA Association made significant contributions to the European technology programme. This work is compiled in this report as follows: the ITER CEA activities and related developments are described in the first section; blankets and material developments for DEMO, long term safety studies are summarised in the second part; the Underlying Technology activities are compiled in the third part of this report. In each section, the tasks are sorted out to respect the European presentation. For an easy reading, appendix 4 gives the list of tasks in alphabetical order with a page reference list. The CEA is in charge of the French Technology programme. Three specific organizational directions of the CEA, located on four sites (see appendix 5) are involves in this programme: Advanced Technologies Direction (DTA), for Material task; Nuclear Reactors Direction (DRN), for Blanket design, Neutronic problems, Safety tasks; Physical Sciences Direction (DSM) uses the competence of the Tore Supra team in the Magnet design and plasma Facing Component field. The CEA programme is completed by collaborations with Technicatome, COMEX-Nucleaire and Ecole Polytechnique. The breakdown of the programme by Directions is presented in figure 1. The allocation of tasks is given in appendix 2 and in appendix 3, the related publications. (author).

  17. Identification of CEA-interacting proteins in colon cancer cells and their changes in expression after irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Byong Chul [Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang (Korea, Republic of); Yeo, Seung Gu [Dept. of Radiation Oncology, Soonchunhyang University College of Medicine, Soonchunhyang University Hospital, Cheonan (Korea, Republic of)

    2017-09-15

    The serum carcinoembryonic antigen (CEA) level has been recognized as a prognostic factor in colorectal cancer, and associated with response of rectal cancer to radiotherapy. This study aimed to identify CEA-interacting proteins in colon cancer cells and observe post-irradiation changes in their expression. CEA expression in colon cancer cells was examined by Western blot analysis. Using an anti-CEA antibody or IgG as a negative control, immunoprecipitation was performed in colon cancer cell lysates. CEA and IgG immunoprecipitates were used for liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis. Proteins identified in the CEA immunoprecipitates but not in the IgG immunoprecipitates were selected as CEA-interacting proteins. After radiation treatment, changes in expression of CEA-interacting proteins were monitored by Western blot analysis. CEA expression was higher in SNU-81 cells compared with LoVo cells. The membrane localization of CEA limited the immunoprecipitation results and thus the number of CEA-interacting proteins identified. Only the Ras-related protein Rab-6B and lysozyme C were identified as CEA-interacting proteins in LoVo and SNU-81 cells, respectively. Lysozyme C was detected only in SNU-81, and CEA expression was differently regulated in two cell lines; it was down-regulated in LoVo but up-regulated in SNU-81 in radiation dosage-dependent manner. CEA-mediated radiation response appears to vary, depending on the characteristics of individual cancer cells. The lysozyme C and Rab subfamily proteins may play a role in the link between CEA and tumor response to radiation, although further studies are needed to clarify functional roles of the identified proteins.

  18. Identification of CEA-interacting proteins in colon cancer cells and their changes in expression after irradiation

    International Nuclear Information System (INIS)

    Yoo, Byong Chul; Yeo, Seung Gu

    2017-01-01

    The serum carcinoembryonic antigen (CEA) level has been recognized as a prognostic factor in colorectal cancer, and associated with response of rectal cancer to radiotherapy. This study aimed to identify CEA-interacting proteins in colon cancer cells and observe post-irradiation changes in their expression. CEA expression in colon cancer cells was examined by Western blot analysis. Using an anti-CEA antibody or IgG as a negative control, immunoprecipitation was performed in colon cancer cell lysates. CEA and IgG immunoprecipitates were used for liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis. Proteins identified in the CEA immunoprecipitates but not in the IgG immunoprecipitates were selected as CEA-interacting proteins. After radiation treatment, changes in expression of CEA-interacting proteins were monitored by Western blot analysis. CEA expression was higher in SNU-81 cells compared with LoVo cells. The membrane localization of CEA limited the immunoprecipitation results and thus the number of CEA-interacting proteins identified. Only the Ras-related protein Rab-6B and lysozyme C were identified as CEA-interacting proteins in LoVo and SNU-81 cells, respectively. Lysozyme C was detected only in SNU-81, and CEA expression was differently regulated in two cell lines; it was down-regulated in LoVo but up-regulated in SNU-81 in radiation dosage-dependent manner. CEA-mediated radiation response appears to vary, depending on the characteristics of individual cancer cells. The lysozyme C and Rab subfamily proteins may play a role in the link between CEA and tumor response to radiation, although further studies are needed to clarify functional roles of the identified proteins

  19. François de Rose (1910 - 2014)

    CERN Multimedia

    Corinne Pralavorio

    2014-01-01

    One of CERN’s founding fathers has passed away.   François de Rose in the ATLAS cavern during his visit to CERN in 2013. Visionaries have the freedom of mind to shape the future when other people’s horizons are obstructed by the present. François de Rose was a visionary. In the aftermath of the Second World War, when Europe was in ruin, when absolutely everything had to be rebuilt, the diplomat understood the importance of reviving fundamental research and, above all, of cooperation on a continental scale as the driving force of this ambition. In a Europe that was just starting to get back on its feet, it would be no mean feat. Nonetheless, François, alongside the prominent physicists of the time, put his energy into making this vision a reality. They lobbied governments for the creation of a centre that would work towards this goal, winning support, and CERN was established in 1954, an achievement of which François was extremely...

  20. Some cogent observations on amoebic hepatopathies using radioactive rose bengal

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, B N; Jha, B K

    1975-08-01

    Amoebic hepatopathies in this paper refers to three clinical syndromes described as hepatic amoebiasis, liver abscess and amoebic hepatitis. Forty-six patients with clinical symptomatology suggestive of amoebic hepatopathy were investigated with /sup 131/I rose bengal. Size, shape, position and parenchymal functions of their livers were estimated by assessing rose bengal blood clearance rate and scanning procedures. It was observed that there was true hepatomegaly and hepatic dysfunction in cases of hepatic abscess but not in amoebic hepatitis patients. Furthermore, hepatic abscess cases always had a ''cold'' area in their liver scans even at very early stage. On the other hand, amoebic hepatitis patients had normal size, shape and function of the liver--which was further confirmed by liver biopsy in five of them. These livers were palpable because of their low anatomical position (Ptosis). All the cases of hepatic abscess (except two) were treated by antiamoebic drugs without resorting to aspiration and serial scans showed complete resolution. Hence it is seen that aspiration in managing these cases (irrespective of the size) in early stages is not indicated at all. Thirty per cent of these patients developed jaundice and again size of the abscess was not critical. Surprisingly, amoebic hepatitis cases also showed improvement to oral anti-amoebic drugs. Liver, if at all involved in these cases, was due to chronic bowel disorders and treatment of bowel gives them symptomatic relief. However, no direct evidence could be brought out to prove existence of amoebic hepatitis by these techniques.

  1. Use of radioimmunodetection of carcinoembryonic antigen (CEA) and ferritin in diagnosis of lung cancer

    International Nuclear Information System (INIS)

    Zamyatin, S.S.; Zakharychev, V.D.

    1989-01-01

    To study the diagnostic value of radioimmunoassay (RIA) of carcinoembryonic antigen (CEA) and ferritin the level of this markers under lung cancer depending on the tumor localization and the process stage is determined. It is shown that determination of CEA and ferritin level in a number of patients with the peripheral lung cancer allows on the confirm the diagnosis. In case of the central cancer an increase of CEA level testifies to the tumor germination into the adjacent organs and lung tissue and allows one to determine the stage and operability of the disease. 10 refs.; 3 tabs

  2. 78 FR 33047 - Humboldt-Toiyabe National Forest, Carson Ranger District Mt. Rose Ski Tahoe-Atoma Area...

    Science.gov (United States)

    2013-06-03

    ... Mt. Rose Ski Tahoe--Atoma Area Environmental Impact Statement AGENCY: Forest Service, USDA. ACTION... the effects of a proposal from Mt. Rose Ski Tahoe (Mt. Rose) to expand its lift and terrain network. The project is located approximately 12 miles west of the intersection of Mt. Rose Highway (Nevada...

  3. Identification of two new races of Diplocarpon rosae Wolf, the causal agent of rose black spot disease

    Science.gov (United States)

    The fungal pathogen, Diplocarpon rosae Wolf, infects only roses (Rosa spp.) and leads to rose black spot disease. Rose black spot is the most problematic disease of outdoor grown roses worldwide, due to the potential for rapid leaf yellowing and defoliation. Plants repeatedly defoliated from black ...

  4. CEA distribution transformer purchasing specifications (DTWG-01,02,03)

    International Nuclear Information System (INIS)

    Fischer, M.

    1999-01-01

    Purchasing specifications for three types of distribution transformers are presented. The specifications were compiled by the Canadian Electricity Association at the suggestion made in 1989 by the Canadian Utilities Material Management Group. The specifications cover pole mounted single phase distribution transformers (DTWG-01), low-profile, single phase, dead-front pad-mounted distribution transformers (DTWG-02), and three phase, dead-front pad-mounted distribution transformers (DTWG-03). The specifications were compiled by a task force of CEA member utilities, using CSA standards as the governing standards in all three cases. The first edition of the purchasing specifications was issued in 1993. The second edition, consisting mainly of revisions based on experiences learned from using the first edition, and the addition of the appropriate clauses of CSA standards, was published in 1998. Based on a three-year average of the number of transformers purchased annually (about 58,000) at an estimated total cost of $ 120 million, use of the Purchasing Specifications is said to have resulted in savings of about 7 per cent or $ 8.4 million

  5. CEA's waste management policy and strategy. Lessons learned - 59201

    International Nuclear Information System (INIS)

    Dall'ava, Didier

    2012-01-01

    Document available in abstract form only. Full text of publication follows: Radioactive wastes are generated during operation as well as during the decontamination and dismantling of CEA's nuclear facility/installation. The safe and responsible management of radioactive wastes at all stages is an essential requirement of the regulatory system. The management covers the whole sequence of operations starting with the generation of waste and ending with its disposal. The disposal here means discarding of waste with no intention for retrieval. It is important to note here that the safety principles and practices that are applicable during the operational phase are also applicable during the decommissioning phase. As the radioactive waste arising is an inevitable outcome of decommissioning work, all the regulatory requirements associated with decommissioning remain in force in waste management. This presentation deals initially with the regulatory standards related to the management of wastes. As the management of radioactive wastes inevitably includes treatment and conditioning of wastes, following treatment and conditioning of wastes, storage, transportation and eventual disposal are the logical outcome of the radioactive wastes, processes are at any time improved based on the feedback experience and the lessons learned. (author)

  6. Report on transparency and nuclear safety - Cadarache CEA centre - 2012

    International Nuclear Information System (INIS)

    2013-01-01

    A first volume proposes a presentation of the Cadarache CEA centre, of its activities and installations, gives a rather detailed overview of measures related to safety and to radiation protection within these activities and installations. It also reports significant events related to safety and to radiation protection which occurred in 2012 and have been declared to the ASN. It discusses the results of release measurements (liquid and gaseous effluents, radiological assessment, and chemical assessment for various installations) and the control of the chemical and radiological impact of these gaseous and liquid effluents on the environment. It addresses the issue of radioactive wastes which are stored in the different nuclear base installations of the Centre, indicates the different measures aimed at limiting the volume of these warehoused wastes and addresses their impact on health and on the environment. Nature and quantities of warehoused wastes are specified. The second volume concerns some specific installations (INB 32 or ATPu, and INB 54 or LPC) which belong to AREVA NC. The same topics are addressed: presentation of the facilities, arrangements regarding safety and radiation protection, significant events related to safety and radiation protection, measurements of effluents and their impact on the environment, warehoused wastes. Remarks and recommendations of the CHSCT are given

  7. Progress in fusion reactors blanket analysis and evaluation at CEA

    International Nuclear Information System (INIS)

    Proust, E.; Gervaise, F.; Carre, F.; Chevereau, G.; Doutriaux, D.

    1986-09-01

    In the frame of the recent CEA studies aiming at the development, evaluation and comparison of solid breeder blanket concepts in view of their adaptation to NET, the evaluation of specific questions related to the first wall design, the present paper examines first the performances of a helium cooled toroidal blanket design for NET, based on innovative Beryllium/Ceramics breeder rod elements. Neutronic and thermo-mechanical optimisation converges on a concept featured by a breeding capability in excess of 1.2, a reasonnable pumping power of 1% and a narrow breeder temperature range (470+-30 deg C of the breeder), the latter being largely independent of the power level. This design proves naturally adapted to ceramic breeder assigned to very strict working conditions, and provides for any change in the thermal and heat transfer characteristics over the blanket lifetime. The final section of the paper is devoted to the evaluation of the heat load poloidal distribution and to the irradiation effects on first wall structural materials

  8. Report on transparency and nuclear safety - Grenoble CEA centre - 2012

    International Nuclear Information System (INIS)

    2013-01-01

    This report presents the different nuclear base installations (INB) of the Grenoble CEA centre, gives an overview of measures regarding safety within these installations (organisation, general arrangements, human and organizational factors, arrangements related to different risks, management of emergency situations, inspections, audits and second-level controls, arrangements and main events specific to the different installations and buildings) and of measures related to radiation protection (organisation and results, main events). It reports the significant events related to safety and radiation protection which occurred in 2012 and were declared to the ASN, and discusses how the return-on-experience has been used. It reports and comments the results of measurements of radiological and chemical gaseous and liquid effluents, of surveys of the environment. It also presents the environmental management approach. The next part addresses the management of radioactive wastes which are warehoused on this site: arrangements aimed at limiting their volume, and at limiting their impact on health and on the environment, waste production and removal, nature and quantities of warehoused wastes. Remarks and recommendations of the CHSCT are given

  9. Demonstration of monoclonal anti-carcinoembryonic antigen (CEA) antibody internalization by electron microscopy, western blotting and radioimmunoassay.

    Science.gov (United States)

    Tsaltas, G; Ford, C H; Gallant, M

    1992-01-01

    One of the important factors affecting the action of monoclonal antibodies (Mabs) or immunoconjugates on tumour sites depends on whether the Mab is internalized by the cancer cells in question. The underexplored subject of internalization is discussed in this paper, and a number of in vitro techniques for investigating internalization are evaluated, using a model which consists of a well characterized anti-carcinoembryonic antigen (anti-CEA) Mab and a number of CEA expressing human cancer cell lines. Employing two alternative radiolabeling assays, evidence for internalization of the anti-CEA Mab by a CEA-positive colorectal cancer cell line (LS174T) was obtained throughout the time intervals examined (5 min to 150 min). Electronmicroscopy employing horseradish-peroxidase labeled anti-CEA Mab and control antibody permitted direct visualization of anti-CEA Mab-related staining in intracellular compartments of a high CEA-expressor human colorectal cell line (SKCO1). Finally Western blots of samples derived from cytosolic and membrane components of solubilized cells from lung and colonic cancer cell lines provided evidence for internalized anti-CEA Mab throughout seven half hour intervals, starting at 5 minutes. Internalized anti-CEA was detected in all CEA expressing cell lines (LS174T, SKCO1, BENN) but not in the case of a very low CEA expressor line (COLO 320).

  10. The Rosa genome provides new insights into the domestication of modern roses.

    Science.gov (United States)

    Raymond, Olivier; Gouzy, Jérôme; Just, Jérémy; Badouin, Hélène; Verdenaud, Marion; Lemainque, Arnaud; Vergne, Philippe; Moja, Sandrine; Choisne, Nathalie; Pont, Caroline; Carrère, Sébastien; Caissard, Jean-Claude; Couloux, Arnaud; Cottret, Ludovic; Aury, Jean-Marc; Szécsi, Judit; Latrasse, David; Madoui, Mohammed-Amin; François, Léa; Fu, Xiaopeng; Yang, Shu-Hua; Dubois, Annick; Piola, Florence; Larrieu, Antoine; Perez, Magali; Labadie, Karine; Perrier, Lauriane; Govetto, Benjamin; Labrousse, Yoan; Villand, Priscilla; Bardoux, Claudia; Boltz, Véronique; Lopez-Roques, Céline; Heitzler, Pascal; Vernoux, Teva; Vandenbussche, Michiel; Quesneville, Hadi; Boualem, Adnane; Bendahmane, Abdelhafid; Liu, Chang; Le Bris, Manuel; Salse, Jérôme; Baudino, Sylvie; Benhamed, Moussa; Wincker, Patrick; Bendahmane, Mohammed

    2018-06-01

    Roses have high cultural and economic importance as ornamental plants and in the perfume industry. We report the rose whole-genome sequencing and assembly and resequencing of major genotypes that contributed to rose domestication. We generated a homozygous genotype from a heterozygous diploid modern rose progenitor, Rosa chinensis 'Old Blush'. Using single-molecule real-time sequencing and a meta-assembly approach, we obtained one of the most comprehensive plant genomes to date. Diversity analyses highlighted the mosaic origin of 'La France', one of the first hybrids combining the growth vigor of European species and the recurrent blooming of Chinese species. Genomic segments of Chinese ancestry identified new candidate genes for recurrent blooming. Reconstructing regulatory and secondary metabolism pathways allowed us to propose a model of interconnected regulation of scent and flower color. This genome provides a foundation for understanding the mechanisms governing rose traits and should accelerate improvement in roses, Rosaceae and ornamentals.

  11. The treatment of effluents; Ameliorations apportees aux traitements des residus radioactifs

    Energy Technology Data Exchange (ETDEWEB)

    Wormser, G; Rodier, J; Robien, E de; Fernandez, N [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1964-07-01

    For several years the French Atomic Energy Commission has been studying with interest problems presented by radio-active effluents. Since high activities have not yet received a definite solution we will deal only, in this paper, with the achievements and research concerning low and medium activity effluents. In the field of the achievements, we may mention the various effluent treatment stations which have been built in France; a brief list will be given together with an outline of their main new features. Thus in particular the latest treatment stations put into operation (Grenoble, Fontenay-aux-Roses, Cadarache) will be presented. From all these recent achievements three subjects will be dealt with in more detail. 1 - The workshop for treating with bitumen the sludge obtained after concentration of radionuclides. 2 - The workshop for treating radioactive solid waste by incineration. 3 - A unit for concentrating radio-active liquid effluents by evaporation. In the field of research, several topics have been undertaken, a list will be given. In most cases the research concerns the concentration of radionuclides with a view to a practical and low cost storage, a concentration involving an efficient decontamination of the aqueous liquids in the best possible economic conditions. For improving the treatments leading to the concentration of nuclides, our research has naturally been concerned with perfecting the treatments used in France: coprecipitation and evaporation. In our work we have taken into account in particular two conditions laid down in the French Centres. 1 - A very strict sorting out of the effluents at their source in order to limit in each category the volume of liquid to be dealt with. 2 - The necessity for a very complete decontamination due to the high population density in our country. In the last past we present two original methods for treating liquid effluents. 1 - The use of ion-exchange resins for liquids containing relatively many salts. The

  12. The CEA and the alternative energies. Press tour 25 and 26 november 1999; Le CEA et les energies alternatives. Voyage de presse les 25 et 26 novembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    Carola, G. [CEA/Grenoble, 38 (France); Ngo, Ch. [CEA, Dir. de la Strategie et de l' Evaluation, 75 - Paris (France); Mermilliod, N.; Serre-Combe, P. [CEA/Grenoble, Dir. des Technologies Avancees, DTA, 38 (France); Sanglan, P. [Air Liquide, 38 - Sassenage (France); De La Graviere, M. [CEA/Cadarache, 13 - Saint-Paul-lez-Durance (France); Dieudonne, O.; Malbranche, Ph. [CEA/Cadarache, Dir. des Reacteurs Nucleaires, DRN, 13 - Saint-Paul-lez-Durance (France)

    1999-11-01

    In the framework of the public information on the CEA center of Cadarache and Grenoble, a presentation of the researches concerning the alternative energies is proposed. The Cea is commissioned by the Public Authorities, to keep the nuclear option open and for the long-dated, to develop renewable energies. In this domain researches on fuel cells and photovoltaic solar energy are performed. The principle and the applications of the fuel cell and the photovoltaic are recalled to introduce the research programs and the partners. (A.L.B.)

  13. Nuclear. In China, the CEA asserts itself as a team leader; Nucleaire: en Chine, le CEA s'impose en meneur de jeu

    Energy Technology Data Exchange (ETDEWEB)

    Dupin, L.

    2011-03-15

    As the French government gave the CEA the responsibility of negotiating the nuclear French-Chinese nuclear strategic partnership, this article outlines the personality of the CEA's chairman, Bernard Bigot, but also the tensions which exist between the two main actors of the French nuclear industry, EDF and Areva, notably about their respective projects of development of a new reactor with China as far as EDF is concerned, and with Japan as far as Areva is concerned. In fact, China is asking France, not to build new reactors but to improve the performance and the safety in the existing ones

  14. Significance of changes of serum NSE and CEA levels in patients with pneumonia and malignant tumors

    International Nuclear Information System (INIS)

    Liu Hengguo; Luo Nanping; Wang Ruishan; Bai Lu

    2005-01-01

    Objective: To investigate the significance of changes of serum NSE and CEA levels in patients with pneumonia and malignant tumors. Methods: Serum NSE (with RIA) and CEA (with ECLIA) levels in patients with pneumonia or various kinds of malignant tumors (altogether 140 patients) and 32 controls. Results: Serum NSE and CEA levels were significantly higher in patients with lung cancer, gastric cancer, renal cancer, brain tumor and pneumonia than those in the controls (P<0.05,P <0. 05 ,P <0. 01, P<0.01, P<0.01). Positive rate of serum NSE highest in patients with pneumonia, followed successively by renal cancer, brain tumor and lung cancer. NSE levels were positively correlated with CEA levels (r=0.29, P<0.05). Conclusion: As a tumor marker, NSE has important clinical significance in the diagnoses of malignant tumor and pneumonia. (authors)

  15. Numerical Platon: A unified linear equation solver interface by CEA for solving open foe scientific applications

    International Nuclear Information System (INIS)

    Secher, Bernard; Belliard, Michel; Calvin, Christophe

    2009-01-01

    This paper describes a tool called 'Numerical Platon' developed by the French Atomic Energy Commission (CEA). It provides a freely available (GNU LGPL license) interface for coupling scientific computing applications to various freeware linear solver libraries (essentially PETSc, SuperLU and HyPre), together with some proprietary CEA solvers, for high-performance computers that may be used in industrial software written in various programming languages. This tool was developed as part of considerable efforts by the CEA Nuclear Energy Division in the past years to promote massively parallel software and on-shelf parallel tools to help develop new generation simulation codes. After the presentation of the package architecture and the available algorithms, we show examples of how Numerical Platon is used in sequential and parallel CEA codes. Comparing with in-house solvers, the gain in terms of increases in computation capacities or in terms of parallel performances is notable, without considerable extra development cost

  16. Numerical Platon: A unified linear equation solver interface by CEA for solving open foe scientific applications

    Energy Technology Data Exchange (ETDEWEB)

    Secher, Bernard [French Atomic Energy Commission (CEA), Nuclear Energy Division (DEN) (France); CEA Saclay DM2S/SFME/LGLS, Bat. 454, F-91191 Gif-sur-Yvette Cedex (France)], E-mail: bsecher@cea.fr; Belliard, Michel [French Atomic Energy Commission (CEA), Nuclear Energy Division (DEN) (France); CEA Cadarache DER/SSTH/LMDL, Bat. 238, F-13108 Saint-Paul-lez-Durance Cedex (France); Calvin, Christophe [French Atomic Energy Commission (CEA), Nuclear Energy Division (DEN) (France); CEA Saclay DM2S/SERMA/LLPR, Bat. 470, F-91191 Gif-sur-Yvette Cedex (France)

    2009-01-15

    This paper describes a tool called 'Numerical Platon' developed by the French Atomic Energy Commission (CEA). It provides a freely available (GNU LGPL license) interface for coupling scientific computing applications to various freeware linear solver libraries (essentially PETSc, SuperLU and HyPre), together with some proprietary CEA solvers, for high-performance computers that may be used in industrial software written in various programming languages. This tool was developed as part of considerable efforts by the CEA Nuclear Energy Division in the past years to promote massively parallel software and on-shelf parallel tools to help develop new generation simulation codes. After the presentation of the package architecture and the available algorithms, we show examples of how Numerical Platon is used in sequential and parallel CEA codes. Comparing with in-house solvers, the gain in terms of increases in computation capacities or in terms of parallel performances is notable, without considerable extra development cost.

  17. Network and system diagrams revisited: Satisfying CEA requirements for causality analysis

    International Nuclear Information System (INIS)

    Perdicoulis, Anastassios; Piper, Jake

    2008-01-01

    Published guidelines for Cumulative Effects Assessment (CEA) have called for the identification of cause-and-effect relationships, or causality, challenging researchers to identify methods that can possibly meet CEA's specific requirements. Together with an outline of these requirements from CEA key literature, the various definitions of cumulative effects point to the direction of a method for causality analysis that is visually-oriented and qualitative. This article consequently revisits network and system diagrams, resolves their reported shortcomings, and extends their capabilities with causal loop diagramming methodology. The application of the resulting composite causality analysis method to three Environmental Impact Assessment (EIA) case studies appears to satisfy the specific requirements of CEA regarding causality. Three 'moments' are envisaged for the use of the proposed method: during the scoping stage, during the assessment process, and during the stakeholder participation process

  18. Evaluation of detection methodology for carcinoembryonic antigen and application of CEA in diagnosis of gastric cancer

    International Nuclear Information System (INIS)

    Wang Enlan; Li Tao

    2005-01-01

    To compare the specificity and sensitivity of different methods in detection of CEA, and to investigate the application of CEA detection in diagnosis of gastric cancer, CEA in serum of 36 patients with gastric cancer and 20 negtive reference serum was detected by ELISA, TR- FIA, RIA and CLIA. The results showed that the specificity of these 4 methods was all 100% and the sensitivity of ELISA was the lowest (19.4%) while CLIA was the highest (44.4%). Therefore, the sensitivity of ELISA should be raised and CEA, besides used as an observation index for curative effects in a part of gastric cancer patients, can not be used in diagnosis of gastric cancer. (authors)

  19. Summary list of CEA notes published by the French Atomic Energy Commission (April 1953 - September 1957)

    International Nuclear Information System (INIS)

    1957-09-01

    This document is a summary list of the bibliographic references of all technical notes (CEA-N) published by the French Atomic Energy Commission between April 1953 and September 1957 (note number, authors, title)

  20. Aeroacoustics research in Europe : the CEAS-ASC report on 2007 highlights

    NARCIS (Netherlands)

    Brouwer, H.H.; Rienstra, S.W.

    2008-01-01

    The Council of European Aerospace Societies (CEAS) Aeroacoustics Specialists Committee (ASC) supports and promotes the interests of the scientific and industrial aeroacoustics community on a European scale and European aeronautics activities internationally. In this context, "aeroacoustics"

  1. Control of effluents and environmental surveillance of the CEA centres. 1997 status

    International Nuclear Information System (INIS)

    1998-06-01

    The environmental quality in the vicinity of CEA facilities is a major concern of the safety policy of the CEA. The aim of this document is to inform the public about the gaseous and liquids radioactive effluents released by the CEA centres under the permission of the ministry. It provides a status of the effluents and of the radioactivity levels measured near the CEA centres in 1997, using air, water, vegetation and milk samples. A comparison is made with the measurements performed during the 1993-1996 period. The data presented comes from the regulatory registers transmitted to the agency for the protection against ionizing radiations (OPRI) which belongs to the ministry of health. (J.S.)

  2. Summary list of CEA notes published by the French Atomic Energy Commission (October 1957 - January 1958)

    International Nuclear Information System (INIS)

    1959-01-01

    This document is a summary list of the bibliographic references of all technical notes (CEA-N) published by the French Atomic Energy Commission between October 1957 and January 1958 (note number, authors, title)

  3. Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer

    Directory of Open Access Journals (Sweden)

    Campos da Paz M

    2012-10-01

    Full Text Available Mariana Campos da Paz,1 Maria de Fátima M Almeida Santos,1 Camila MB Santos,2 Sebastião W da Silva,2 Lincoln Bernardo de Souza,3 Emília CD Lima,3 Renata C Silva,1 Carolina M Lucci,1 Paulo César Morais,2 Ricardo B Azevedo,1 Zulmira GM Lacava11Instituto de Ciências Biológicas; 2Instituto de Física, Universidade de Brasília, Brasília, DF, Brazil; 3Instituto de Química, Universidade Federal de Goiás, Goiânia, GO, BrazilAbstract: Nanosized maghemite particles were synthesized, precoated (with dimercaptosuccinic acid and surface-functionalized with anticarcinoembryonic antigen (anti-CEA and successfully used to target cell lines expressing the CEA, characteristic of colorectal cancer (CRC cells. The as-developed nanosized material device, consisting of surface decorated maghemite nanoparticles suspended as a biocompatible magnetic fluid (MF sample, labeled MF-anti-CEA, was characterized and tested against two cell lines: a high-CEA expressing cell line (LS174T and a low-CEA expressing cell line (HCT116. Whereas X-ray diffraction was used to assess the average core size of the as-synthesized maghemite particles (average 8.3 nm in diameter, dynamic light scattering and electrophoretic mobility measurements were used to obtain the average hydrodynamic diameter (550 nm and the zeta-potential (−38 mV of the as-prepared and maghemite-based nanosized device, respectively. Additionally, surface-enhanced Raman spectroscopy (SERS was used to track the surface decoration of the nanosized maghemite particles from the very first precoating up to the attachment of the anti-CEA moiety. The Raman peak at 1655 cm−1, absent in the free anti-CEA spectrum, is the signature of the anti-CEA binding onto the precoated magnetic nanoparticles. Whereas MTT assay was used to confirm the low cell toxicity of the MF-anti-CEA device, ELISA and Prussian blue iron staining tests performed with both cell lines (LS174T and HCT116 confirm that the as-prepared MF-anti-CEA

  4. Comparison of Ablation Predictions for Carbonaceous Materials Using CEA and JANAF-Based Species Thermodynamics

    Science.gov (United States)

    Milos, Frank S.

    2011-01-01

    In most previous work at NASA Ames Research Center, ablation predictions for carbonaceous materials were obtained using a species thermodynamics database developed by Aerotherm Corporation. This database is derived mostly from the JANAF thermochemical tables. However, the CEA thermodynamics database, also used by NASA, is considered more up to date. In this work, the FIAT code was modified to use CEA-based curve fits for species thermodynamics, then analyses using both the JANAF and CEA thermodynamics were performed for carbon and carbon phenolic materials over a range of test conditions. The ablation predictions are comparable at lower heat fluxes where the dominant mechanism is carbon oxidation. However, the predictions begin to diverge in the sublimation regime, with the CEA model predicting lower recession. The disagreement is more significant for carbon phenolic than for carbon, and this difference is attributed to hydrocarbon species that may contribute to the ablation rate.

  5. Foire aux questions: Bourse de recherche 2017 du CRDI | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1) Si l'on décide de m'attribuer une bourse de recherche, aurai-je besoin d'un permis de travail ? Veuillez lire les détails sur ce sujet sous la rubrique Admissibilité à la page Web de l'appel. Vous remarquerez que d'importantes modifications ont été apportées aux critères d'admissibilité cette année. 2) Je suis étudiant à la ...

  6. The Prognostic Significance of Pretreatment Serum CEA Levels in Gastric Cancer: A Meta-Analysis Including 14651 Patients

    Science.gov (United States)

    Deng, Kai; Yang, Li; Hu, Bing; Wu, Hao; Zhu, Hong; Tang, Chengwei

    2015-01-01

    Background Carcinoembryonic antigen (CEA) is commonly used as a serum tumor marker in clinical practice; however, its prognostic value for gastric cancer patients remains uncertain. This meta-analysis was performed to assess the prognostic value of CEA and investigate CEA as a tumor marker. Methods PubMed, EMBASE and other databases were searched for potentially eligible studies. Forty-one studies reporting the prognostic effect of pretreatment serum CEA expression in gastric cancer patients were selected. Data on 14651 eligible patients were retrieved for the meta-analysis. Based on the data extracted from the available literature, the hazard ratio (HR) and 95% confidence interval (CI) for an adverse prognosis were estimated for gastric cancer patients with elevated pretreatment serum levels of CEA (CEA+) relative to patients with normal pretreatment CEA levels (CEA-). Results The CEA+ patients had a significantly poorer prognosis than the CEA- patients in terms of overall survival (OS: HR 1.716, 95% CI 1.594 - 1.848, P 0.05). In the pooled analyses of multivariate-adjusted HRs, the results suggested that pretreatment serum CEA may be an independent prognostic factor in gastric cancer (OS: HR 1.681, 95% CI 1.425 - 1.982; DSS: HR 1.900, 95% CI 1.441 - 2.505; DFS: HR 2.579, 95% CI 1.935 - 3.436). Conclusion/Significance The meta-analysis based on the available literature supported the association of elevated pretreatment serum CEA levels with a poor prognosis for gastric cancer and a nearly doubled risk of mortality in gastric cancer patients. CEA may be an independent prognostic factor for gastric cancer patients and may aid in determining appropriate treatment which may preferentially benefit the CEA+ patients. PMID:25879931

  7. CEA A BIOCHEMICAL MARKER FOR DIAGNOSIS AND PROGNOSIS OF GASTROINTESTINAL CANCER

    OpenAIRE

    Prathibha; Vishnu Datt

    2016-01-01

    Serum tumor markers (TM) are widely used for diagnosis and monitoring of treatment of cancer. Carcinoembryonic Antigen (CEA) is one of the most widely investigated tumor markers in gastrointestinal (GI) cancers. Estimation of circulating tumor markers is a non- invasive quantitative method. Serum levels of CEA were studied for diagnosis and prognosis of gastrointestinal malignancies. 140 subjects were undertaken out of which 35 normal and remaining 105 were GI cancer patients. Ser...

  8. Comparison of CA15-3 and CEA in breast cancer

    International Nuclear Information System (INIS)

    Rajkovaca, Z.; Mijatovic, J.; Matavulj, A.; Kovacevic, P.; Ponorac, N.

    2002-01-01

    Aim: Tumor markers are potentially powerful means for obtaining information about cancers whilst causing minimal morbidity, inconvenience and cost. CA 15-3 and CEA are considered useful tumor markers in monitoring breast cancer patients. The aim of this study was to evaluate which of these two markers are in better correlate with the disease in patients surgically treated for breast cancer. Material and Methods: We retrospectively reviewed values of CA15-3 and CEA in 342 patients (median age 52.18 years, range 27-78 years) with surgically treated and pathologically proven breast cancer. CA15-3 and CEA was measured by radioimmunoassay. CA15-3 levels above 30 U/ml and CEA levels above 5 ng/ml were considered as positive values. Results: Out of 342 patients, 86 had elevated CA15-3 levels (sensitivity: 25.1%) and 68 of 342 patients had positive CEA levels (sensitivity 19.9%). Two hundred thirty seven (237) of the patients suffering from breast cancer (69.3%) did not have metastatic disease. In this group CA15-3 sensitivity was 94.5%, while CEA sensitivity was 87.3%. One hundred and five (105) patients (30.7%) had metastatic disease. In this group, CA15-3 sensitivity was 69.5% and CEA sensitivity was 36.2% (P < 0.05). With regard to the correlation of the two tumor markers with clinical course patients had significantly higher levels of CA15-3 than of CEA in metastatic breast cancer. Conclusion: This result suggests CA15-3 to be the more sensitive and more specific of the two tumor markers for metastatic breast cancer detection and monitoring

  9. Scientific evaluation at the French Atomic Energy Commission (CEA). 2005-2006 annual report

    International Nuclear Information System (INIS)

    2006-01-01

    This report aims at presenting the scientific evaluation activities carried out at the CEA during the years 2005-2006. The evaluation system is described in detail. It comprises two aspects: the evaluation of the scientific policy implemented by the scientific Council and by the visiting committee of the CEA, and the evaluation of the laboratories, performed by a pool of 36 scientific councils. The evaluation by external and independent parties is the key point of this system. This document makes a status of the evaluations performed in 2005 and 2006. It presents a synthesis of the conclusions of the evaluation authorities. The actions implemented by the CEA to take into consideration the recommendations are also reported with the improvements noticed. The two topics examined by the scientific Committee and by the visiting committee were dealing with the energy domain, which is a strategic issue for the CEA. The examination of the researches on future nuclear reactors and on new energy technologies have shown the major role played by the CEA in the recent advances in these domains. About 95% of the laboratories activity was examined during the 2002-2005 period. The richness of the remarks and recommendations made by the scientific councils should allow the CEA to improve the quality and relevance of its research works. The start-up of the 2006-2009 evaluation cycle has been the occasion to modify the evaluation of some research domains in order to take into account the evolution of programs. The evaluation system of the CEA is highly consistent with the AERES principles. Its implementation, adapted to each type of activity (fundamental research, applied research, technological developments) allows the CEA to follow up a permanent improvement approach. (J.S.)

  10. Summary 1998. Releases control and environment monitoring for the CEA Centers

    International Nuclear Information System (INIS)

    1998-01-01

    In the framework of its environmental policy, the CEA aims at reduce as weak as possible, in regards to the technological and economic needs, its activities impacts on the people and the environment. This paper contributes to the public information on the radioactive gaseous and liquid releases during the year 1998. It presents data on the releases and the radioactivity levels around the CEA sites and gathers the associated regulation and monitoring methods. (A.L.B.)

  11. CEA assay in the follow-up of patients with bowel cancer and breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Vassilakos, P J; Glaros, D C; Sdougou-Christacopoulou, J; Dermentzoglou, F; Samaras, V [Democritus Nuclear Research Center, Athens (Greece)

    1978-01-01

    The findings gave high CEA values only in 33.3% of patients from the group with bowel cancer and in 30.7% from that with breast cancer which confirms the earlier suggestion that the CEA is not selective enough to identify the early stage of the disease. The test can be valuable as a prognostic marker capable of suggesting the succesful response to therapy and can give evidence of the recurrence of the disease in early diagnosis.

  12. Design of a Model Execution Framework: Repetitive Object-Oriented Simulation Environment (ROSE)

    Science.gov (United States)

    Gray, Justin S.; Briggs, Jeffery L.

    2008-01-01

    The ROSE framework was designed to facilitate complex system analyses. It completely divorces the model execution process from the model itself. By doing so ROSE frees the modeler to develop a library of standard modeling processes such as Design of Experiments, optimizers, parameter studies, and sensitivity studies which can then be applied to any of their available models. The ROSE framework accomplishes this by means of a well defined API and object structure. Both the API and object structure are presented here with enough detail to implement ROSE in any object-oriented language or modeling tool.

  13. I-131 rose bengal excretion test is not dead

    International Nuclear Information System (INIS)

    Antico, V.F.; Denhartog, P.; Ash, J.M.; Gilday, D.L.; Houle, S.

    1985-01-01

    One hundred and thirty I-131 Rose Bengal Excretion Studies (RBI) were performed on 84 patients over nine years. In 90% (56/60) of cases with biliary atresia, the 72-hour RBI was less than or equal to 7%. In only 12.5% (3/24) of cases with neonatal hepatitis was the 72-hour RBI less than or equal to 7%. The accuracy of the test was 91% with a specificity of 88%. Thirty patients later were studied following a Kasai procedure. The RBI test reliably predicted the patency of the anastomosis. The authors conclude that the 72-hour RBI is a reliable test in the diagnosis of biliary atresia and in the documentation of biliary patency following surgery, provided adequate care is taken in stool collection and measurement

  14. Mutation induced with ion beam irradiation in rose

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, H. E-mail: yhiroya@nias.affrc.go.jp; Nagatomi, S.; Morishita, T.; Degi, K.; Tanaka, A.; Shikazono, N.; Hase, Y

    2003-05-01

    The effects of mutation induction by ion beam irradiation on axillary buds in rose were investigated. Axillary buds were irradiated with carbon and helium ion beams, and the solid mutants emerged after irradiation by repeated cutting back. In helium ion irradiation, mutations were observed in plants derived from 9 buds among 56 irradiated buds in 'Orange Rosamini' and in plants derived from 10 buds among 61 irradiated buds in 'Red Minimo'. In carbon ion, mutations were observed in plants derived from 12 buds among 88 irradiated buds in 'Orange Rosamini'. Mutations were induced not only in higher doses but also in lower doses, with which physiological effect by irradiation was hardly observed. Irradiation with both ion beams induced mutants in the number of petals, in flower size, in flower shape and in flower color in each cultivar.

  15. The Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE)

    DEFF Research Database (Denmark)

    Rubin, Katrine Hass; Holmberg, Teresa; Rothmann, Mette Juel

    2015-01-01

    The risk-stratified osteoporosis strategy evaluation study (ROSE) is a randomized prospective population-based study investigating the effectiveness of a two-step screening program for osteoporosis in women. This paper reports the study design and baseline characteristics of the study population....... 35,000 women aged 65-80 years were selected at random from the population in the Region of Southern Denmark and-before inclusion-randomized to either a screening group or a control group. As first step, a self-administered questionnaire regarding risk factors for osteoporosis based on FRAX......(®) was issued to both groups. As second step, subjects in the screening group with a 10-year probability of major osteoporotic fractures ≥15 % were offered a DXA scan. Patients diagnosed with osteoporosis from the DXA scan were advised to see their GP and discuss pharmaceutical treatment according to Danish...

  16. Kepustakawanan dalam The Name of The Rose karya Umberto Eco

    Directory of Open Access Journals (Sweden)

    Laksmi Laksmi

    2005-10-01

    Full Text Available The Name of the Rose, a detective novel, is set by some issues on librarianship during the Middle Age in Europe. By using discourse analysis approach, I try to know how far the concept of the librarianship was understood at that time—in the novel—based on the understanding of some concepts, starting from “library”, “development system”, “collection handling”, which includes “classification”, “censorship system” and “librarians’ professionalism”, until some matters on borrowing and using collection. Besides, this analysis is aimed at identifying cultural values related to the librarianship. The conclusion shows that the librarianship has an important role in providing suspense elements in a detective novel.

  17. Synchronization of ;light-sensitive; Hindmarsh-Rose neurons

    Science.gov (United States)

    Castanedo-Guerra, Isaac; Steur, Erik; Nijmeijer, Henk

    2018-04-01

    The suprachiasmatic nucleus is a network of synchronized neurons whose electrical activity follows a 24 h cycle. The synchronization phenomenon (among these neurons) is not completely understood. In this work we study, via experiments and numerical simulations, the phenomenon in which the synchronization threshold changes under the influence of an external (bifurcation) parameter in coupled Hindmarsh-Rose neurons. This parameter ;shapes; the activity of the individual neurons the same way as some neurons in the brain react to light. We corroborate this experimental finding with numerical simulations by quantifying the amount of synchronization using Pearson's correlation coefficient. In order to address the local stability problem of the synchronous state, Floquet theory is applied in the case where the dynamic systems show continuous periodic solutions. These results show how the sufficient coupling strength for synchronization between these neurons is affected by an external cue (e.g. light).

  18. Transcriptome database resource and gene expression atlas for the rose

    Science.gov (United States)

    2012-01-01

    Background For centuries roses have been selected based on a number of traits. Little information exists on the genetic and molecular basis that contributes to these traits, mainly because information on expressed genes for this economically important ornamental plant is scarce. Results Here, we used a combination of Illumina and 454 sequencing technologies to generate information on Rosa sp. transcripts using RNA from various tissues and in response to biotic and abiotic stresses. A total of 80714 transcript clusters were identified and 76611 peptides have been predicted among which 20997 have been clustered into 13900 protein families. BLASTp hits in closely related Rosaceae species revealed that about half of the predicted peptides in the strawberry and peach genomes have orthologs in Rosa dataset. Digital expression was obtained using RNA samples from organs at different development stages and under different stress conditions. qPCR validated the digital expression data for a selection of 23 genes with high or low expression levels. Comparative gene expression analyses between the different tissues and organs allowed the identification of clusters that are highly enriched in given tissues or under particular conditions, demonstrating the usefulness of the digital gene expression analysis. A web interface ROSAseq was created that allows data interrogation by BLAST, subsequent analysis of DNA clusters and access to thorough transcript annotation including best BLAST matches on Fragaria vesca, Prunus persica and Arabidopsis. The rose peptides dataset was used to create the ROSAcyc resource pathway database that allows access to the putative genes and enzymatic pathways. Conclusions The study provides useful information on Rosa expressed genes, with thorough annotation and an overview of expression patterns for transcripts with good accuracy. PMID:23164410

  19. Weed control in rose-scented geranium (Pelargonium spp).

    Science.gov (United States)

    Kothari, Sushil K; Singh, Chandra P; Singh, Kamla

    2002-12-01

    Abstract: Field investigations were carried out during 1999 and 2000 to identify effective chemical/ cultural methods of weed control in rose-scented geranium (Pelargonium spp). The treatments comprised pre-emergence applications of oxyfluorfen (0.15, 0.20 and 0.25 kg AI ha(-1)) and pendimethalin (0.50, 0.75 and 1.00kg AI ha(-1)), successive hand weeding, hoeing and mulching using spent of lemon grass (at 5 tonnes ha(-1)) 45 days after planting (DAP), three hand-weedings 30, 60 and 90 DAP, weed-free (frequent manual weeding) and weedy control. Broad-leaf weeds were more predominant than grass and sedge weeds, accounting for 85.8% weed density and 93.0% weed dry weight in 1999 and 77.2% weed density and 93.9% weed dry weight in 2000. Unrestricted weed growth significantly reduced geranium oil yield, by 61.6% and 70.6% in 1999 and 2000, respectively. Pre-emergence application of pendimethalin (0.75-1.00 kgAI ha(-1)) or oxyfluorfen (0.25 kg AI ha(-1)), successive hand-weeding, hoeing and mulching and three hand-weedings were highly effective in reducing weed density and dry weight and gave oil yield comparable to the weed-free check. Application of oxyfluorfen (0.15 or 0.20 kg AI ha(-1)) and pendimethalin (0.50 kg AI ha(-1)) were less effective in controlling the weed species in geranium. None of the herbicides impaired the quality of rose-scented geranium oil measured in terms of citronellol and geraniol content.

  20. Diagnostic test pepsinogen I and combination with tumor marker CEA in gastric cancer

    Science.gov (United States)

    Sembiring, J.; Sarumpaet, K.; Ganie, R. A.

    2018-03-01

    Gastric cancer (GC) is the fifth leading cause of cancer and the third leading cause of cancer-related mortality globally. Human pepsinogens (HP) are considered promising serological biomarkers for the screening of atrophic gastritis (AG) and GC. HP are biochemically and immunochemically classified into two groups: pepsinogen I (PG I) and PG II. Carcinoembryonic antigen (CEA) is a glycoprotein, which is present in normal mucosal cells but increased amounts are associated with adenocarcinoma, especially colorectal cancer. CEA in combination with other tumour markers can be used in pre-operative staging and thereby assist in the planning of the type of surgery required and future management options. The purpose of this study was to diagnose test PG I and combination with tumor marker CEA in 32 patients suspected with GC. There was a significant difference in levels of CEA between GC group with non-GC with a value p <0.001. PGI sensitivity was 70.58% and specificity 93.3%. The sensitivity of PGI and CEA combination of 94.1% and specificity 80%. The area of AUC obtained was 92.7% at 95% confidence interval (82.7-100%). This AUC value indicated that the value of diagnostic accuracy of the PGI and CEA combinations of 92.7%.

  1. La responsabilité comme mode de gouvernement néolibéral : l’exemple des programmes d’aide aux familles aux États-Unis de 1980 à nos jours

    Directory of Open Access Journals (Sweden)

    Philippe Fournier

    2015-01-01

    penche sur des travaux plus contemporains, notamment ceux du sociologue britannique Nikolas Rose qui se préoccupe de la responsabilité en tant que modalité gouvernementale au sein du néolibéralisme. La troisième partie met en relief les particularités du néolibéralisme américain. En vue de cerner les pratiques et discours associés à la responsabilité de façon plus précise, la dernière partie examine l’un des principaux programmes d’aide sociale aux États-Unis, l’Aid to Families with Dependent Children (AFDC, devenu le Temporary Assistance for Needy Families (TANF en 1996, des années 1980 jusqu’à aujourd’hui.

  2. Safety Training: Sensibilisation aux gestes et postures de travail

    CERN Multimedia

    Laetitia Laddada

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt.Nous vous proposons un nouveau cours de sécurité lié aux manutentions manuelles (durée 1 jour) : Sensibilisation aux gestes et postures de travail. Si vous êtes amené à manipuler régulièrement des charges lourdes ou volumineuses, cette formation peut vous aider à prévenir les lésions musculaires ou dorsales. A l'issue de cette formation, vous serez capable d'adopter et d'appliquer les principes de base de sécurité physique et d'&e...

  3. Safety Training: Sensibilisation aux gestes et postures de travail

    CERN Multimedia

    Laetitia Laddada

    2004-01-01

    Nous vous proposons un nouveau cours de sécurité lié aux manutentions manuelles (durée 1 jour) : Sensibilisation aux gestes et postures de travail. Si vous êtes amené à manipuler régulièrement des charges lourdes ou volumineuses, cette formation peut vous aider à prévenir les lésions musculaires ou dorsales. A l'issue de cette formation, vous serez capable d'adopter et d'appliquer les principes de base de sécurité physique et d'économie d'efforts dans les manipulations d'objets. Les cours sont pris en charge par la Commission de Sécurité. L'inscription EDH est obligatoire. Pour plus d'information, veuillez consulter les pages Formation & Développement (Groupe Sécurité). FORMATION EN SECURITE SAFETY TRAINING Laetitia Laddada 73811 - 79236 safety.training@cern.ch

  4. The Rose (Rosa hybrida) NAC Transcription Factor 3 Gene, RhNAC3, Involved in ABA Signaling Pathway Both in Rose and Arabidopsis

    OpenAIRE

    Jiang, Guimei; Jiang, Xinqiang; Lü, Peitao; Liu, Jitao; Gao, Junping; Zhang, Changqing

    2014-01-01

    Plant transcription factors involved in stress responses are generally classified by their involvement in either the abscisic acid (ABA)-dependent or the ABA-independent regulatory pathways. A stress-associated NAC gene from rose (Rosa hybrida), RhNAC3, was previously found to increase dehydration tolerance in both rose and Arabidopsis. However, the regulatory mechanism involved in RhNAC3 action is still not fully understood. In this study, we isolated and analyzed the upstream regulatory seq...

  5. Situation 2002: release monitoring and surveillance of environment of Cea centers; Bilan 2002: controle des rejets et surveillance de l'environnement des centres CEA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This publication renders an account of the situation of the releases of liquid and gaseous radioactive effluents, for the year 2002, as well as the radioactivity levels measured in the vicinity of Cea centers through the systematic surveillance of atmosphere, waters, vegetation and milk. An analysis on five years allows to follow their evolution. (N.C.)

  6. Mesures de spectrométrie et de dosimétrie neutron aux postes de travail pour l'étalonnage de dosimètres individuels PGP-DIN

    OpenAIRE

    Itié, C.; Muller, H.; Asselineau, B.; Médioni, R.; Crovisier, P.; Valier-Bradier, P.; Groetz, J. E.; Piot, J.

    2002-01-01

    International audience; (ManuAcrit r e p le 3 juillet 2002, accepté le 29 septembre 2002) Dans le cadre de la mise en application des recommandations décrites dans la publication 60 de la CIPR, des mesures de spectrométrie neutron ont été réalisées à plusieurs postes de travail au CEA de Valduc. Le but de ces mesures était la détermination de nouveaux coefficients d'étalonnage h affecter aux dosimètres individuels neutron PGP-DIN afin de restituer correctement les doses reçues par les opérate...

  7. ''1995/2010: site drainage and nuclear facilities dismantling program'' result 2001

    International Nuclear Information System (INIS)

    2001-01-01

    A drainage and dismantling planing with the corresponding wastes management, has been decided for the CEA of Fontenay aux roses, in 1995. It will end in 2010. This document presents the main evolutions occurred since october 2000. (A.L.B.)

  8. ''1995/2010: site drainage and nuclear facilities dismantling program'' result 2001; ''1995/2010: programme d'assainissement du site et de demantelement des installations nucleaire'' bilan 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    A drainage and dismantling planing with the corresponding wastes management, has been decided for the CEA of Fontenay aux roses, in 1995. It will end in 2010. This document presents the main evolutions occurred since october 2000. (A.L.B.)

  9. Tore Supra: a tokamak with superconducting coils for the toroidal field

    International Nuclear Information System (INIS)

    Turck, B.

    1984-01-01

    It is under construction on the site of CEN/Cadarache for the EURATOM-CEA Association. The design has been lead by a group including teams of the DRFC of Fontenay-aux-Roses and Grenoble and the DPh/PE-STI of CEN/Saclay [fr

  10. Towards the rose genome sequence and its use in research and breeding

    NARCIS (Netherlands)

    Foucher, F.; Hilbrand-Saint Oyant, L.; Hamama, L.; Sakr, S.; Baudino, S.; Caissard, J.P.; Smulders, M.J.M.; Debener, T.; Riek, de J.; Torres, A.F.; Desnoyé, B.

    2015-01-01

    Rose is one of the most economically important ornamental crops worldwide. Rosa sp. can become a model for woody ornamentals. Its genome size is relatively small (560 Mb), its genetic history with ploïdy events is well documented, and rose has a short life for a woody plant. Furthermore, different

  11. 76 FR 25322 - Oklahoma Rose Water LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-05-04

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13854-000] Oklahoma Rose Water LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On September 30, 2010, Oklahoma Rose Water LLC filed an...

  12. Effect of gamma-irradiation of cuttings on the growth and morphological variability of garden roses

    International Nuclear Information System (INIS)

    Klimenko, Z.K.; Zykov, K.I.; Shanin, Eh.V.

    1977-01-01

    Action of γ-radiation on cuttings of two species of garden roses has been studied. Doses ranging from 3 to 10 kR were found to be most effective in producing mutations. Fourteen highly ornamental rose species having a modified coloration have been selected and reproduced

  13. Lifting All Boats? Finance Litigation, Education Resources, and Student Needs in the Post-"Rose" Era

    Science.gov (United States)

    Sims, David P.

    2011-01-01

    "Rose v. Council for Better Education" (1989) is often considered a transition point in education finance litigation, heralding an era of increasing concern for measurable adequacy of education across a broad spectrum of student needs. Prior research suggests that post-Rose lawsuits had less effect on the distribution of school spending…

  14. 78 FR 42153 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for...

    Science.gov (United States)

    2013-07-15

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0081] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for Public Comments AGENCY... COMPASS ROSE is: Intended Commercial Use Of Vessel: ``Sailboat charters six passengers or less...

  15. Algorithms to estimate the rose of directions of a spatial fibre system

    DEFF Research Database (Denmark)

    Kiderlen, Markus; Pfrang, A.

    2005-01-01

    The directional measure (which is up to normalization the rose of directions) is used to quantify anisotropy of stationary fibre processes in three-dimensional space. There exist a large number of approaches to estimate this measure from the rose of intersections (which is the mean number...

  16. 33 CFR 165.1312 - Security Zone; Portland Rose Festival on Willamette River.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; Portland Rose Festival on Willamette River. 165.1312 Section 165.1312 Navigation and Navigable Waters COAST GUARD... § 165.1312 Security Zone; Portland Rose Festival on Willamette River. (a) Location. The following area...

  17. Extraction method for the determination of inorganic iodides in Rose Bengal labelled with 131I

    International Nuclear Information System (INIS)

    Lengyel, J.; Krtil, J.; Vecernik, J.

    1982-01-01

    An extraction method for the determination of inorganic iodides in Rose Bengal preparations labelled with 131 I is described. The method is based on the quantitative extraction of Rose Bengal into chloroform from acidic medium while the inorganic iodides remain in the aqueous phase. The method is simple, rapid, and reproducible. (author)

  18. Downy mildew of Double Knock Out® rose caused by Peronospora sparsa in Maryland

    Science.gov (United States)

    Roses are one of the most popular and economically important ornamental plants worldwide. In the last 17 years, Knock Out® roses (Rosa x 'Radtko') have been widely used in public and private gardens across the U.S. due to their disease resistance, self-cleaning, drought tolerance and multiple-bloomi...

  19. The value of KRAS mutation testing with CEA for the diagnosis of pancreatic mucinous cysts

    Science.gov (United States)

    Kadayifci, Abdurrahman; Al-Haddad, Mohammad; Atar, Mustafa; Dewitt, John M.; Forcione, David G.; Sherman, Stuart; Casey, Brenna W.; Fernandez-del Castillo, Carlos; Schmidt, C. Max; Pitman, Martha B.; Brugge, William R.

    2016-01-01

    Background and aims: Pancreatic cyst fluid (PCF) CEA has been shown to be the most accurate preoperative test for detection of cystic mucinous neoplasms (CMNs). This study aimed to assess the added value of PCF KRAS mutational analysis to CEA for diagnosis of CMNs. Patients and methods: This is a retrospective study of prospectively collected endoscopic ultrasonography (EUS) fine-needle aspiration (FNA) data. KRAS mutation was determined by direct sequencing or equivalent methods. Cysts were classified histologically (surgical cohort) or by clinical (EUS or FNA) findings (clinical cohort). Performance characteristics of KRAS, CEA and their combination for detection of a cystic mucinous neoplasm (CMN) and malignancy were calculated. Results: The study cohort consisted of 943 patients: 147 in the surgical cohort and 796 in the clinical cohort. Overall, KRAS and CEA each had high specificity (100 % and 93.2 %), but low sensitivity (48.3 % and 56.3 %) for the diagnosis of a CMN. The positivity of KRAS or CEA increased the diagnostic accuracy (80.8 %) and AUC (0.84) significantly compared to KRAS (65.3 % and 0.74) or CEA (65.8 % and 0.74) alone, but only in the clinical cohort (P < 0.0001 for both). KRAS mutation was significantly more frequent in malignant CMNs compared to histologically confirmed non-malignant CMNs (73 % vs. 37 %, P = 0.001). The negative predictive value of KRAS mutation was 77.6 % in differentiating non-malignant cysts. Conclusions: The detection of a KRAS mutation in PCF is a highly specific test for mucinous cysts. It outperforms CEA for sensitivity in mucinous cyst diagnosis, but the data does not support its routine use. PMID:27092317

  20. Fitoplancton del Parque Nacional Las Tablas de Daimiel. II. Las cianofíceas, los dinoflagelados, las criptofíceas, las crisofíceas y las xantofíceas

    Directory of Open Access Journals (Sweden)

    Rojo, Carmen

    1999-12-01

    Full Text Available Las Tablas de Daimiel National Park is a semiarid wetland that exhibits a high biodiversity but is suffering an inexorable eutrophication process. The study of the phytoplankton in this wetland is interesting because of its hydrological fluctuations (drought period until 1996 and its trophic condition. This papers shows the taxonomy, dynamic, and ecology of microalgae in five áreas of the Park from 1996 to 1998, which allow comparisons to be made between the present state and the 1992-1993 period. Twelve taxa of Cyanophyta, 4 of Dynophyceae, 8 of Cryptophyceae, 5 of Chrysophyceae and one of Xanthophyceae were found. Almost all species have been already cited in Spain and are typical for eutrophic environments. Cyanophyceae and Cryptophyceae were the most important groups (Planktothrix agardhii, Anabaenopsis elenkinii, Cryptomonas erosa as the most common algae. Moreover, oscillatorial Cyanophyceae (in 1992 have been replaced by N-fixing nostocal ones, related to the high level of pollution found in recent years.El Parque Nacional Las Tablas de Daimiel es un humedal semiárido, importante reserva de biodiversidad que, sin embargo, está sufriendo un inexorable proceso de eutrofización. Su estado trófico, así como los cambios hidrológicos (sequía hasta 1996, hacen especialmente interesante el estudio de su microflora. Por ello, se ha llevado a cabo este trabajo sobre las poblaciones fitoplanctónicas en cinco puntos del Parque desde 1996 a 1998, que permite además la comparación con su estado en 1992-1993. Se encontraron 12 táxones de Cyanophyta, 4 de Dynophyceae, 8 de Cryptophyceae, 5 de Chrysophyceae y uno de Xanthophyceae. Casi todas las especies están citadas en España y son propias de ambientes eutróficos. Los grupos mejor representados fueron las cianobacterias y criptofíceas (Planktothrix agardhii, Anabaenopsis elenkinii y Cryptomonas erosa fueron las especies más conspicuas. Además, se observa un cambio de cianobacterias

  1. Induction Heating on Dynamic Tensile Tests in CEA Saclay

    International Nuclear Information System (INIS)

    Averty, X.; Yvon, P.; Duguay, C.; Pizzanelli, J. P.; Basini, V.

    2001-01-01

    The LCMI (Laboratory for characterization of irradiated materials), located in CEA from Saclay, is in charge of the mechanical tests on irradiated materials. The dynamic tensile testing machine, in a hot cell equipped with two remote handling, has been first improved in 1995, to fulfill the French safety programs on Reactivity Initiated Accident (RIA). One objective of this machine is to obtain mechanical property data on current Zircaloy cladding types needed to quality the cladding's response under RIA or LOCA transient loading and thermal conditions. For the RIA, this means testing at strain rates up to 5 s' and heating rates up to 200 degree centigree-s''-1, while for Loss of Coolant Accidents (LOCA) testing at strain rates of 10''-3 s''-1 and heating rates of 20 degree centigree s''-1 would be appropriate. The tensile samples are machined with a spark erosion machine, directly from pieces of cladding previously de fueled. Two kinds of samples can be machined in the cladding. Axial samples in order to test axial mechanical characteristics Ring samples in order to test transverse mechanical characteristics, more representative of RIA conditions. On one hand, the axial tensile tests were performed using the Joule effect, and heating rates up to about 500 degree centigree .s''-1 were obtained. This enabled us to perform the axial tests in a satisfactory manner. On the other hand, the tensile ring were first performed in a vertical furnace with a heating rate about 0.2 degree centigree.s''-1 and a thermal stability about 1 degree centigree. For temperatures above 480 degree centigree, the mechanical characteristics showed a sharp drop which could be attributed to irradiation defect annealing. Therefore we have recently developed an induction heating system to reach heating rates high enough (200 degree centigree.s''-1) to prevent any significant annealing before performing the ring tensile tests. To apply a uniaxial tangential tension, two matching half

  2. A new solid phase enzyme immuno assay using a monoclonal antibody for CEA determinations in patients with various carcinomas

    International Nuclear Information System (INIS)

    Staab, H.J.; Glock, S.; Hornung, A.

    1982-01-01

    The clinical validity of carcinoembryonic antigen (CEA) determination with a new solid phase enzyme immuno assay using a monoclonal antibody (EIA-m) in comparison with a common CEA radioimmunoassay with polyclonal antisera (RIA) was investigated for primary diagnosis in 123 patients with various malignancies and in the postoperative followup of 83 patients with gastrointestinal cancers over a period of about one year. The normal range of the new CEA test in which CEA was directly measured without any further extraction, was calculated from the CEA distribution of 147 healthy blood donors and found to be 0-1.5 μg CEA/l. Besides a very fine reproducibility the CEA-m exhibited a pronounced specificity for CEA from patients with colorectal cancers compared with the RIA. Using a cut-off level of >=1.5 μg CEA/l serum with the EIA-m, the test gave a specificity of 76% with a sensitivity of 72% for preoperative serum specimen of 82 patients with colorectal cancers and a control group of 53 patients with nonmalignant gastrointestinal diseases. In this groups of patients the EIA-m was superior to the RIA test which had a sensitivity of 75% at a specificity of 62% using a threshold of >=2.0 μg CEA/l serum. In the followup studies 3 basic tendencies of the CEA time courses well distinguished from each other could be established for both CEA-Tests. Tumor progression, characterized by steadily increasing CEA levels were evident in 20/23 cases with recurrent disease while decreasing or essentially unchanged CEA levels correlated with NED status in the patients. Furthermore 3/23 cases with metastasis in the followup had initial CEA increases indicated by EIA-m, 3-5 months before this increase of the CEA values was evident with the RIA. Transient CEA elevations, not associated with malignant growth, were found less frequently with the new EIA-m compared to the RIA. (orig.) [de

  3. Maladies reliées aux loisirs aquatiques

    Science.gov (United States)

    Sanborn, Margaret; Takaro, Tim

    2013-01-01

    Résumé Objectif Passer en revue les facteurs de risque, la prise en charge et la prévention des maladies reliées aux loisirs aquatiques en pratique familiale. Sources des données Des articles originaux et de synthèse entre janvier 1998 et février 2012 ont été identifiés à l’aide de PubMed et des expressions de recherche en anglais water-related illness, recreational water illness et swimmer illness. Message principal Il y a un risque de 3 % à 8 % de maladies gastrointestinales (MGI) après la baignade. Les groupes à risque élevé de MGI sont les enfants de moins de 5 ans, surtout s’ils n’ont pas été vaccinés contre le rotavirus, les personnes âgées et les patients immunodéficients. Les enfants sont à plus grand risque parce qu’ils avalent plus d’eau quand ils nagent, restent dans l’eau plus longtemps et jouent dans l’eau peu profonde et le sable qui sont plus contaminés. Les adeptes des sports dans lesquels le contact avec l’eau est abondant comme le triathlon et le surf cerf-volant sont aussi à risque élevé et même ceux qui s’adonnent à des activités impliquant un contact partiel avec l’eau comme la navigation de plaisance et la pêche ont un risque de 40 % à 50 % fois plus grand de MGI par rapport à ceux qui ne pratiquent pas de sports aquatiques. Il y a lieu de faire une culture des selles quand on soupçonne une maladie reliée aux loisirs aquatiques et l’échelle clinique de la déshydratation est utile pour l’évaluation des besoins de traitement chez les enfants affectés. Conclusion Les maladies reliées aux loisirs aquatiques est la principale cause de MGI durant la saison des baignades. La reconnaissance que la baignade est une source importante de maladies peut aider à prévenir les cas récurrents et secondaires. On recommande fortement le vaccin contre le rotavirus chez les enfants qui se baignent souvent.

  4. Clinical significance of determination of serum SA, CEA and CRP levels in patients with colo-rectal cancer

    International Nuclear Information System (INIS)

    Cai Jie; Hu Junyan; Sun Shuming; Cheng Benkun

    2007-01-01

    Objective: To investigate the clinical usefulness of determination of serum SA, CEA and CRP levels in patients with colorectal cancer. Methods: Serum SA (with colorimetry), CEA (with CLIA) and CRP (with ILIA) levels were measured in 120 patients with colo-rectal cancer. Results: (1) Serum SA, CEA and CRP levels increased significantly as the disease stage advanced from Duke A through Duke D. (2) As the malignancy of the growth advanced from well-differentiated to anaplastic, the serum SA and CRP levels increased significantly while the reverse was true for serum CEA levels. (3) In 68 post-operative patients followed 1-5 years, the serum levels of SA, CEA and CRP were significantly higher in the patients with recurrence (n=29) than those in patients without recurrence (n=39) (P<0.01). Conclusion: Serum SA CEA and CRP levels were closely related to the disease process in patients with colo-rectal cancer. (authors)

  5. Evaluation of the reliability concerning the identification of human factors as contributing factors by a computer supported event analysis (CEA)

    International Nuclear Information System (INIS)

    Wilpert, B.; Maimer, H.; Loroff, C.

    2000-01-01

    The project's objectives are the evaluation of the reliability concerning the identification of Human Factors as contributing factors by a computer supported event analysis (CEA). CEA is a computer version of SOL (Safety through Organizational Learning). Parts of the first step were interviews with experts from the nuclear power industry and the evaluation of existing computer supported event analysis methods. This information was combined to a requirement profile for the CEA software. The next step contained the implementation of the software in an iterative process of evaluation. The completion of this project was the testing of the CEA software. As a result the testing demonstrated that it is possible to identify contributing factors with CEA validly. In addition, CEA received a very positive feedback from the experts. (orig.) [de

  6. Disease resistance breeding in rose: current status and potential of biotechnological tools.

    Science.gov (United States)

    Debener, Thomas; Byrne, David H

    2014-11-01

    The cultivated rose is a multispecies complex for which a high level of disease protection is needed due to the low tolerance of blemishes in ornamental plants. The most important fungal diseases are black spot, powdery mildew, botrytis and downy mildew. Rose rosette, a lethal viral pathogen, is emerging as a devastating disease in North America. Currently rose breeders use a recurrent phenotypic selection approach and perform selection for disease resistance for most pathogen issues in a 2-3 year field trial. Marker assisted selection could accelerate this breeding process. Thus far markers have been identified for resistance to black spot (Rdrs) and powdery mildew and with the ability of genotyping by sequencing to generate 1000s of markers our ability to identify markers useful in plant improvement should increase exponentially. Transgenic rose lines with various fungal resistance genes inserted have shown limited success and RNAi technology has potential to provide virus resistance. Roses, as do other plants, have sequences homologous to characterized R-genes in their genomes, some which have been related to specific disease resistance. With improving next generation sequencing technology, our ability to do genomic and transcriptomic studies of the resistance related genes in both the rose and the pathogens to reveal novel gene targets to develop resistant roses will accelerate. Finally, the development of designer nucleases opens up a potentially non-GMO approach to directly modify a rose's DNA to create a disease resistant rose. Although there is much potential, at present rose breeders are not using marker assisted breeding primarily because a good suite of marker/trait associations (MTA) that would ensure a path to stable disease resistance is not available. As our genomic analytical tools improve, so will our ability to identify useful genes and linked markers. Once these MTAs are available, it will be the cost savings, both in time and money, that will

  7. L’ethnologue aux prises avec les archives - Introduction

    Directory of Open Access Journals (Sweden)

    Marie-Dominique Mouton

    2008-08-01

    Full Text Available Les textes présentés ici invitent à une réflexion sur les matériaux de terrain et plus largement sur la relation qui unit l’ethnologue aux archives, qu’il s’agisse des siennes, données vivantes, inspiratrices de sa recherche, de celles de ses aînés, devenues objets d’étude après leur dépôt dans une institution, ou de toutes les autres archives, constituées et rassemblées, à différentes époques, dans des perspectives administratives, juridiques, historiques ou religieuses, envisagées ici au tr...

  8. In vitro propagation of Hylocereus monacanthus (Lem. Britton and Rose

    Directory of Open Access Journals (Sweden)

    Laura Belem Montiel-Frausto

    2016-04-01

    Full Text Available The application of tissue culture contributes to the rapid and massive propagation of economically important species and serves as a basic platform for production strategies. The objective of this work was to establish the in vitro propagation of Hylocereus monacanthus (Lem. Britton and Rose. The seeds were in vitro germinated and then the apical segments containing the apex and areoles were taken and placed in culture medium MS with BAP (1.0, 2.0 and 4.0 mg l-1 and IAA (0.5 mg l-1 separately and combined for the multiplication phase. For rooting an MS culture medium with different  concentrations of inorganic salts (50, 75 and 100% and IBA (0.1 mg l-1 was used. In vitro plants obtained were planted in greenhouse for their acclimatization. The percentage of seeds germination was 70% with 6% of microbial contamination. With 1 mg l-1 BAP, the best results were obtained for the in vitro multiplication of H. monacanthus. In all treatments 100% of rooted shoots were obtained and only a significant difference was observed for root length with the addition of 0.1 mg l-1 IBA. The average survival of plants transferred to substrate was 97.1%. The results of this work offer an alternative of propagation for H. monacanthus, which will contribute to the establishment of commercial plantations and other studies at the laboratory level.   Keywords: pitahaya, shoot tip, cacti

  9. Losio Antioksidan Buah Naga Merah (Hylocereus polyrhizus Britton and Rose

    Directory of Open Access Journals (Sweden)

    Amanda Angelina Sinaga

    2015-04-01

    Full Text Available Hylocereus polyrhizus Britton and Rose (Red dragon fruit has been shown to have antioxidant activity which contains vitamin C, polyphenol, and flavonoid. This research was aimed to investigate antioxidant effectivity from H. polyrhizus in form of lotion. Lotion were made with 5 concentrations from H. polyrhizus methanol extract which were 0.04; 0.08; 0.16; 0.32 and 0.64%. The antioxidant activity of lotion was measured using DPPH method. The research showed that H. polyrhizus methanol extract had antioxidant activity with inhibition concentration were 19.99±0.33; 25.01±0.08; 39.14±0.04; 66.69±0.12 and 83.37±0.05. The result showed significant differences on antioxidant activity. The physical stability observation of five formula with cycling test method showed unstability because of discolouration (oxidation. As well as the methods of mechanical test showed unstability of lotion because saponification process.

  10. Characterization and consequences from CEA nuclear fuel cycle facilities effluents releases - 1995 up to 2007 period

    International Nuclear Information System (INIS)

    Ferreira, Nelson Luiz Dias; Fonseca, Lizandra Pereira de Souza

    2009-01-01

    Discharges to the environment of airborne and/or liquid radioactive effluents from the normal operation of nuclear facilities can become a potential source of radiation exposure to humans. The highest exposed members of the public are defined as the critical group. The requirements for the control and monitoring of radioactive discharges to the environment and the degree of environmental monitoring required are linked to the assessed critical group dose. The assessed dose can be compared to dose constraint, which is a fraction of the annual effective dose to members of the public, as well as the level of exemption specified by the National Commission for Nuclear Energy (CNEN). Effluents releases from the Centro Experimental Aramar (CEA) facilities are registered and described at CEA Effluent Report, semestrally sent to CNEN. Basically, that report provides information related to the type and the quantity of chemical and radioactive substances released to the environment due the routine operation of CEA nuclear fuel cycle facilities (LEI - Isotopic Enrichment Laboratory, USIDE - Pilot Plant for Industrial Verification of Uranium Enrichment and LABMAT - Nuclear Materials Laboratory). CEA Annual Effluent Report includes assessment of the annual effective doses for members of the critical group for the CEA site. This work presents the characterization of the radioactive release source terms and a historical of the critical group annual doses from 1995 up to 2007. (author)

  11. How to Add Value to your Business with CEA: A Practical Approach

    Directory of Open Access Journals (Sweden)

    Daniel Cardenas

    2010-04-01

    Full Text Available Companies are always trying to differentiate themselves from the rest of the pack by applying different strategies such as improving customer service, increasing the efficiency of their operations, or reducing their costs. Most of the time, however, these goals are competing against each other for scarce resources, and managers often need to decide to concentrate on one. A small company can effectively and simultaneously accomplish these goals for a fraction of the cost by implementing communications-enabled business processes or solutions, which are a set of technology components that add real-time networking functionality to applications. One particular implementation of this framework is the one provided by Coral CEA. Coral CEA is a business ecosystem anchored around CEA functionalities that are offered as building blocks, out-of-the-box components that link the capabilities and intelligence of networks platforms with the power of current applications to provide a new set of features and functionalities. In this article, we show how a small company called Rezact, located in the ski resort town of Mont-Tremblant, Quebec, successfully implemented CEA capabilities within its own operations using Coral CEA services.

  12. CEA in activated macrophages. New diagnostic possibilities for tumor markers in early colorectal cancer.

    Science.gov (United States)

    Japink, Dennis; Leers, Mathie P G; Sosef, Meindert N; Nap, Marius

    2009-08-01

    Serum tumor markers show low sensitivity, making them unsuitable for early detection of cancer. Activated macrophages (AM) from peripheral blood can accumulate tumor marker substances and facilitate early detection in prostate cancer. Here it was investigated whether carcinoembryonic antigen (CEA)-containing macrophages (CEACM) can be used to detect colorectal cancer (CRC) at earlier stages than can serum CEA. Peripheral blood was collected from patients with CRC (n=48), inflammatory colorectal disease (n=5) and from healthy controls (n=18). After separating and labeling AM with CD14-APC/CD16-FITC, AM were intracellularly labeled with anti-CEA antibody and flow cytometrically analyzed. Serum CEA and C-reactive protein (CRP) were measured. The fraction-size of CEACM discriminated between controls and CRC patients, irrespective of AJCC stage (AJCC stage I-IV, pCEA values were significantly elevated in AJCC stage II, III and IV (p=0.02, 0.006 and <0.0001, respectively). Combining CEACM with CRP levels separated CRC from inflammatory colorectal disease. CEACM combined with CRP appears to have diagnostic potential in early CRC.

  13. A three-dimensional pin-wise analysis for CEA ejection accident

    Energy Technology Data Exchange (ETDEWEB)

    Park, Guen-Tae; Park, Min-Ho; Park, Jin-Woo; Um, Kil-Sup; Choi, Tong-Soo [KEPCO NF, Daejeon (Korea, Republic of)

    2016-10-15

    The ejection of a control element assembly (CEA) with high reactivity worth causes the sudden insertion of reactivity into the core. Immediately after the CEA ejection, the nuclear power of the reactor dramatically increases in an exponential behavior until the doppler effect becomes important and turns the reactivity balance and power down to lower levels. The 3-D CEA ejection analysis methodology has been developed using the multi-dimensional code coupling system, CHASER, which couples three dimensional core neutron kinetics code ASTRA, subchannel analysis code THALES, and fuel performance analysis code FROST using message passing interface (MPI). This paper presents the pin-by-pin level analysis result with the 3-D CEA ejection analysis methodology using the CHASER. The pin-by-pin level analysis consists of DNBR, enthalpy and Pellet/Clad Mechanical Interaction (PCMI) analysis. All the evaluations are simulated for APR1400 plant loaded with PLUS7 fuel. In this paper, the pin-by-pin analysis using the multidimensional core transient code, CHASER, is presented with respect to enthalpy, DNBR and PCMI for APR1400 plant loaded with PLUS7 fuel. For the pin-by-pin enthalpy and DNBR analysis, the quarter core for HFP case or 15 - 20 assemblies around the most severe assembly for part powers or HZP cases are selected. And PCMI calculation is performed for all the rods in the whole core during a conservative time period. The pin-by-pin analysis results show that the regulatory guidelines of CEA ejection accident are satisfied.

  14. Monsieur Etienne Blanc Premier vice-président de la Région Auvergne-Rhône-Alpes Délégué aux finances, à l'administration générale, aux économies budgétaires et aux politiques transfrontalières

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2017-01-01

    Monsieur Etienne Blanc Premier vice-président de la Région Auvergne-Rhône-Alpes Délégué aux finances, à l'administration générale, aux économies budgétaires et aux politiques transfrontalières

  15. Using RNA-Seq to assemble a rose transcriptome with more than 13,000 full-length expressed genes and to develop the WagRhSNP 68k Axiom SNP array for rose (Rosa L.)

    NARCIS (Netherlands)

    Koning, C.F.S.; Esselink, G.; Vukosavljev, M.; Westende, van 't W.P.C.; Gitonga, V.W.; Krens, F.A.; Voorrips, R.E.; Weg, van de W.E.; Schulz, D.; Debener, T.; Maliepaard, C.A.; Arens, P.F.P.; Smulders, M.J.M.

    2015-01-01

    In order to develop a versatile and large SNP array for rose, we set out to mine ESTs from diverse sets of rose germplasm. For this RNA-Seq libraries containing about 700 million reads were generated from tetraploid cut and garden roses using Illumina paired-end sequencing, and from diploid Rosa

  16. Chemistry of complexing molecules and environment. Report of the working group of the Cea ''mission environment''

    International Nuclear Information System (INIS)

    Petit, J.C.

    1998-01-01

    The Working group 'Chemistry of Complexing Molecules and Environment' of the Mission Environment (AG/ENV) identified themes for an original positioning of CEA on important issues of environmental research if a sufficiently strong demand appears. The research of CEA on the environment should be complementary to actions undertaken by other partners (official institutions, research organizations and industrial firms). The themes suggested are: the synthesis of new chelating molecules and new materials having specific properties, with the support of theoretical chemistry and modeling, analytical physical chemistry and speciation of species in relation to their eco-toxicity and their biogeochemical mobility in the natural environment. These themes, illustrated by examples of actions in progress at CEA or likely to be launched quickly, draw largely from recognized competences of the teams, generally developed for finalized nuclear applications: experimental, theoretical and instrumental competences. (author)

  17. Mechanical modelling of PCI with FRAGEMA and CEA finite element codes

    International Nuclear Information System (INIS)

    Joseph, J.; Bernard, Ph.; Atabek, R.; Chantant, M.

    1983-01-01

    In the framework of their common program, CEA and FRAGEMA have undertaken the mechanical modelization of PCI. In the first step two different codes, TITUS and VERDON, have been tested by FRAGEMA and CEA respectively. Whereas the two codes use a finite element method to describe the thermomechanical behaviour of a fuel element, input models are not the same for the two codes: to take into account the presence of cracks in UO 2 , an axisymmetric two dimensional mesh pattern and the Druecker-Prager criterion are used in VERDON and a 3D equivalent method in TITUS. Two rods have been studied with these two methods: PRISCA 04bis and PRISCA 104 which were ramped in SILOE. The results show that the stresses and strains are the same with the two codes. These methods are further applied to the complete series of the common ramp test rods program of FRAGEMA and CEA. (author)

  18. Radioimmunoscintigraphy with I-131-labelled anti-CEA monclonal antibody in colorectal cancer patients

    International Nuclear Information System (INIS)

    Xie Tianhao

    1988-01-01

    Twenty three colorectal carcinoma and two benign polyposis patients with operatively and histologically proven were studied by radioimmunoscintigraphy, using anti-CEA monoclonal antibodies (C14-17 and C50) radiolabeled with I-131 . Computer assisted processing for the subtraction of Tc-99m background radioactivity was used to enhance the detection and localization of tumor which is visualized by immune scintigraphy. The size of tumor and the ratios of tumor to nontumor (T/NT) are two very important factors for the external immunoscintigraphy. The antibody uptake and retention in tumor are likely to depend on the degree of vascularity and diffusion into the viable tumor mass. Based upon the obtained results, the sensitivity of the method (true-poditive) was 91%, its specificity (true-negative) was 100%. This study thus indicates that radioimmunoscintigraphy of cancer with radioactive anti-CEA monoclonal antibody is very uaeful in the diagnoses of patients with CEA-containing neoplasms

  19. Thermal-hydraulic investigations on the CEA-ENEA DEMO relevant helium cooled poloidal blanket

    International Nuclear Information System (INIS)

    Dell'Orco, G.; Polazzi, G.; Vallette, F.; Proust, E.; Eid, M.

    1994-01-01

    The CEA-ENEA design of an Helium Cooled Solid Breeder Blanket (HCSBB) for the DEMO reactor, with a breeder in tube (BIT) poloidal arrangement, is based on the use of lithium ceramic pellets, the ENEA γ-LiAlO 2 or the CEA Li 2 ZrO 3 . Due to the geometry of the DEMO reactor plasma chamber, these breeder bundles are adapted to the Vacuum Vessel with a strong poloidal curvature. This curvature influences the thermal-hydraulic behaviour of the coolant flowing inside the bundle. The paper presents the CEA-ENEA first results of the experimental and theoretical programme, aiming at optimizing the breeder module thermal hydraulic design. (author) 6 refs.; 7 figs.; 1 tab

  20. Updated on effluents releases of the CEA nuclear fuel cycle facilities - 1995 to 2010 period

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Nelson Luiz Dias [Centro Tecnologico da Marinha em Sao Paulo (CTMSP) Sao Paulo, SP (Brazil)

    2011-07-01

    The environmental impact assessment of the Centro Experimental Aramar (CEA) facilities has been presented in a former work, based on the measured effluent releases data, for the period from 1995 to 2007. This work shows the update up to 2010. The effluents releases to the environment result from the routine operation of CEA nuclear fuel cycle facilities (LEI - Isotopic Enrichment Laboratory, USIDE - Pilot Plant for Industrial Verification of Uranium Enrichment and LABMAT - Nuclear Materials Laboratory). Basically, this work presents the radioactive release source terms, as described at the CEA Effluent Report sent to the National Commission for Nuclear Energy (CNEN) each semester, and a historical assessment of the critical group annual doses from 1995 up to 2010. The assessed doses are compared to the maximum dose constraint as well as to the exemption level specified by CNEN. (author)

  1. Updated on effluents releases of the CEA nuclear fuel cycle facilities - 1995 to 2010 period

    International Nuclear Information System (INIS)

    Ferreira, Nelson Luiz Dias

    2011-01-01

    The environmental impact assessment of the Centro Experimental Aramar (CEA) facilities has been presented in a former work, based on the measured effluent releases data, for the period from 1995 to 2007. This work shows the update up to 2010. The effluents releases to the environment result from the routine operation of CEA nuclear fuel cycle facilities (LEI - Isotopic Enrichment Laboratory, USIDE - Pilot Plant for Industrial Verification of Uranium Enrichment and LABMAT - Nuclear Materials Laboratory). Basically, this work presents the radioactive release source terms, as described at the CEA Effluent Report sent to the National Commission for Nuclear Energy (CNEN) each semester, and a historical assessment of the critical group annual doses from 1995 up to 2010. The assessed doses are compared to the maximum dose constraint as well as to the exemption level specified by CNEN. (author)

  2. Cationic Phosphorus Dendrimer Enhances Photodynamic Activity of Rose Bengal against Basal Cell Carcinoma Cell Lines.

    Science.gov (United States)

    Dabrzalska, Monika; Janaszewska, Anna; Zablocka, Maria; Mignani, Serge; Majoral, Jean Pierre; Klajnert-Maculewicz, Barbara

    2017-05-01

    In the last couple of decades, photodynamic therapy emerged as a useful tool in the treatment of basal cell carcinoma. However, it still meets limitations due to unfavorable properties of photosensitizers such as poor solubility or lack of selectivity. Dendrimers, polymers widely studied in biomedical field, may play a role as photosensitizer carriers and improve the efficacy of photodynamic treatment. Here, we describe the evaluation of an electrostatic complex of cationic phosphorus dendrimer and rose bengal in such aspects as singlet oxygen production, cellular uptake, and phototoxicity against three basal cell carcinoma cell lines. Rose bengal-cationic dendrimer complex in molar ratio 5:1 was compared to free rose bengal. Obtained results showed that the singlet oxygen production in aqueous medium was significantly higher for the complex than for free rose bengal. The cellular uptake of the complex was 2-7-fold higher compared to a free photosensitizer. Importantly, rose bengal, rose bengal-dendrimer complex, and dendrimer itself showed no dark toxicity against all three cell lines. Moreover, we observed that phototoxicity of the complex was remarkably enhanced presumably due to high cellular uptake. On the basis of the obtained results, we conclude that rose bengal-cationic dendrimer complex has a potential in photodynamic treatment of basal cell carcinoma.

  3. Assessment and Application of the ROSE Code for Reactor Outage Thermal-Hydraulic and Safety Analysis

    International Nuclear Information System (INIS)

    Liang, Thomas K.S.; Ko, F.-K.; Dai, L.-C.

    2001-01-01

    The currently available tools, such as RELAP5, RETRAN, and others, cannot easily and correctly perform the task of analyzing the system behavior during plant outages. Therefore, a medium-sized program aiming at reactor outage simulation and evaluation, such as midloop operation (MLO) with loss of residual heat removal (RHR), has been developed. Important thermal-hydraulic processes involved during MLO with loss of RHR can be properly simulated by the newly developed reactor outage simulation and evaluation (ROSE) code. The two-region approach with a modified two-fluid model has been adopted to be the theoretical basis of the ROSE code.To verify the analytical model in the first step, posttest calculations against the integral midloop experiments with loss of RHR have been performed. The excellent simulation capacity of the ROSE code against the Institute of Nuclear Energy Research Integral System Test Facility test data is demonstrated. To further mature the ROSE code in simulating a full-sized pressurized water reactor, assessment against the WGOTHIC code and the Maanshan momentary-loss-of-RHR event has been undertaken. The successfully assessed ROSE code is then applied to evaluate the abnormal operation procedure (AOP) with loss of RHR during MLO (AOP 537.4) for the Maanshan plant. The ROSE code also has been successfully transplanted into the Maanshan training simulator to support operator training. How the simulator was upgraded by the ROSE code for MLO will be presented in the future

  4. Basic studies on the hepatobiliary scintigraphy with 123I-rose bengal

    International Nuclear Information System (INIS)

    Narabayashi, Isamu; Ito, Yasuhiko; Otsuka, Nobuaki; Muranaka, Akira; Konno, Katsunobu.

    1979-01-01

    The purpose of this investigation is to evaluate the values of 123 I-rose bengal. sup(99m)Tc-labels for the hepatobiliary radiopharmaceutical are not fully satisfied because of greater urinary excretion, especially in cases of hyperbilirubinemia. 123 I is a lower gamma ray energy emitter more suitable for imaging and has a short half life with 13 hours. Commercially obtained rose bengal was purified using Sephadex G-25 column on gelfiltration. 123 I-rose bengal was prepared using iodine exchange reaction between nonradioactive rose bengal and Na 123 I. Radiochemical purity of 123 I-rose bengal was examined by paper chromatography. Biological distribution of 123 I-rose bengal in rabbits at 1 hours after intravenous injection indicated that the tracer was cleared from the blood to the liver, thereafter excreted into the small intestine through the common bile duct. Hepatic uptake and excretion of activity has been measured for 60 minutes using a scintillation camera in conjunction with a VTR system. There existed no significant relative to those of 131 I-rose bengal. Serial scintigraphic images showed satisfactorily better images even in a rabbit with complete obstructive jaundice. (author)

  5. Anti-cancer effects of bioactive compounds from rose hip fruit in human breast cancer cell lines

    OpenAIRE

    Zhong, Lijie

    2017-01-01

    Rose hips have long been used in human diets as a food ingredient and supplement. Their multiple medical properties, which have been attributed to their abundant carotenoid composition, have attracted widespread scientific attention. This thesis examined the carotenoid composition in rose hips from five rose species. The anti-cancer effect of different carotenoid fractions from rose hips was investigated in human breast cancer cell lines, using the natural variation in carotenoid content in h...

  6. Overview of CEA research in the field of radionuclides migration; Syntheses des recherches menees par le CEA sur la migration des radionucleides

    Energy Technology Data Exchange (ETDEWEB)

    Poinssot, Ch; Trotignon, L; Tevissen, E

    2006-07-01

    This report presents a synthetic status of the researches conducted within the Nuclear Energy Division (CEA/DEN) in the field of radionuclides migration in three specific areas which have been chosen for their representativeness and potential impact: the migration of RN in PWR reactors, the migration of RN from a deep geological repository and the migration processes in the surface environments. In addition, some status is given about more generic research which is conducted in the field of RN speciation in the aqueous phase and at the interfaces and regarding chemistry / transport couplings. Additional information about the human and technical means involved in these fields of research in CEA/DEN is finally given in the Appendix. (authors)

  7. Uropathogenic E. coli Exploit CEA to Promote Colonization of the Urogenital Tract Mucosa

    Science.gov (United States)

    Muenzner, Petra; Kengmo Tchoupa, Arnaud; Klauser, Benedikt; Brunner, Thomas; Putze, Johannes; Dobrindt, Ulrich; Hauck, Christof R.

    2016-01-01

    Attachment to the host mucosa is a key step in bacterial pathogenesis. On the apical surface of epithelial cells, members of the human carcinoembryonic antigen (CEA) family are abundant glycoproteins involved in cell-cell adhesion and modulation of cell signaling. Interestingly, several gram-negative bacterial pathogens target these receptors by specialized adhesins. The prototype of a CEACAM-binding pathogen, Neisseria gonorrhoeae, utilizes colony opacity associated (Opa) proteins to engage CEA, as well as the CEA-related cell adhesion molecules CEACAM1 and CEACAM6 on human epithelial cells. By heterologous expression of neisserial Opa proteins in non-pathogenic E. coli we find that the Opa protein-CEA interaction is sufficient to alter gene expression, to increase integrin activity and to promote matrix adhesion of infected cervical carcinoma cells and immortalized vaginal epithelial cells in vitro. These CEA-triggered events translate in suppression of exfoliation and improved colonization of the urogenital tract by Opa protein-expressing E. coli in CEA-transgenic compared to wildtype mice. Interestingly, uropathogenic E. coli expressing an unrelated CEACAM-binding protein of the Afa/Dr adhesin family recapitulate the in vitro and in vivo phenotype. In contrast, an isogenic strain lacking the CEACAM-binding adhesin shows reduced colonization and does not suppress epithelial exfoliation. These results demonstrate that engagement of human CEACAMs by distinct bacterial adhesins is sufficient to blunt exfoliation and to promote host infection. Our findings provide novel insight into mucosal colonization by a common UPEC pathotype and help to explain why human CEACAMs are a preferred epithelial target structure for diverse gram-negative bacteria to establish a foothold on the human mucosa. PMID:27171273

  8. An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492

    Energy Technology Data Exchange (ETDEWEB)

    Brunel, Guy; Denis, Dominique; Boulet, Alain [Commissariat a l' energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)

    2013-07-01

    The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m{sup 2} allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the

  9. The evaluation of diagnostic value of the tumor markers: CCSA-2 and CEA in colorectal cancer.

    Science.gov (United States)

    Knychalski, Bartłomiej; Lukieńczuk, Tadeusz

    2012-02-01

    Finding the biomarker or biomarkers with high sensitivity and specificity in colorectal cancer, and thus a high diagnostic value will determine their clinical usefulness in clinical practice. An effective noninvasive blood test would be an ideal method to detect colorectal cancer. Discovered in 2007 a novel tumor marker CCSA-2 showes a promising results in patients with colorectal cancer. THE AIM OF THE STUDY was the evaluation of diagnostic and clinical value of a novel marker - colon cancer specific antigen-2 (CCSA-2) in colorectal adenocarcinoma in comparison to carcinoembryonic antigen (CEA) in patients operated during the years 2008 to 2010 at Wrocław Medical University 1st Department and Clinic of General, Gastroenterological and Endocrinologic Surgery. The study was performed on 40 patients with colorectal cancer and 40 patients in control group consisted of healthy subjects who had colonoscopy examinations with negative results (no pathology in the colon was found). The obtained results were statistically analyzed using nonparametric tests - Mann Whitney U and Kruskal-Wallis and Spearman's rank correlation coefficients. To determine the clinical value of CCSA-2 and CEA in those groups, their sensitivity and specifity was evaluated using ROC analysis. This analysis determines the accuracy and diagnostic value of both tests. There was a positive correlation between markers in patients with colorectal cancer and a statistically significant relationship according to which respondents with higher concentrations of CCSA-2 also have higher concentrations of CEA (R=0.754, ptumor markers increase and correlate with the clinical progression of the disease. Accuracy of CCSA-2 test using ROC analysis showed a slightly lower measurement of antigen CCSA-2 as diagnostic value in colorectal cancer in comparison to measurement of antigen CEA (accuracy of tests: CCSA-2 - 52%, CEA - 60%). CCSA-2 as a single tumor marker has a low diagnostic value in colorectal cancer because

  10. Development of radiopharmaceuticals based on aptamers: selection and characterization of DNA aptamers for CEA

    International Nuclear Information System (INIS)

    Correa, C.R.; Andrade, A.S.R.; Augusto-Pinto, L.; Goes, A.M.

    2011-01-01

    Colorectal cancer is among the top four causes of cancer deaths worldwide. Carcinoembryonic antigen (CEA) is a complex intracellular glycoprotein produced by about 90% of colorectal cancers. CEA has been identified as an attractive target for cancer research because of its pattern of expression in the surface cell and its likely functional role in tumorigenesis. Research on the rapid selection of ligands based on the SELEX (systematic evolution of ligands by exponential enrichment) forms the basis for the development of high affinity and high specificity molecules, which can bind to surface determinants of tumour cells, like CEA. The oligonucleotides ligands generated in this technique are called aptamers. Aptamers can potentially find applications as therapeutic or diagnostic tools for many kind of diseases, like a tumor. Aptamers offer low immunogenicity, good tumour penetration, rapid uptake and fast systemic clearance, which favour their application as effective vehicles for radiotherapy. In addition aptamers can be labeled with different radioactive isotopes. The aim of this work was select aptamers binding to the CEA tumor marker. The aptamers are obtained through by SELEX, in which aptamers are selected from a library of random sequences of synthetic DNA by repetitive binding of the oligonucleotides to target molecule (CEA). Analyses of the secondary structure of the aptamers were determined using the m fold toll. Three aptamers were selected to binding assay with target cells. These aptamers were confirmed to have affinity and specific binding for T84 cell line (target cell), showed by confocal imaging. We are currently studying the potential efficacy of these aptamers as targeted radiopharmaceuticals, for use as imaging agents or therapeutic applications. The development of aptamers specific to CEA open new perspectives for colorectal cancer diagnosis and treatment. Acknowledgments: This investigation was supported by the Centro de Desenvolvimento da

  11. Development of radiopharmaceuticals based on aptamers: selection and characterization of DNA aptamers for CEA

    Energy Technology Data Exchange (ETDEWEB)

    Correa, C.R.; Andrade, A.S.R., E-mail: antero@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Augusto-Pinto, L. [BioAptus, Belo Horizonte, MG (Brazil); Goes, A.M., E-mail: goes@icb.ufmg.br [Departamento de Imunologia e Bioquimica. Instituto de Ciencias Biologicas. Universidade Federal de Minas Gerais. Belo Horizonte, MG (Brazil)

    2011-07-01

    Colorectal cancer is among the top four causes of cancer deaths worldwide. Carcinoembryonic antigen (CEA) is a complex intracellular glycoprotein produced by about 90% of colorectal cancers. CEA has been identified as an attractive target for cancer research because of its pattern of expression in the surface cell and its likely functional role in tumorigenesis. Research on the rapid selection of ligands based on the SELEX (systematic evolution of ligands by exponential enrichment) forms the basis for the development of high affinity and high specificity molecules, which can bind to surface determinants of tumour cells, like CEA. The oligonucleotides ligands generated in this technique are called aptamers. Aptamers can potentially find applications as therapeutic or diagnostic tools for many kind of diseases, like a tumor. Aptamers offer low immunogenicity, good tumour penetration, rapid uptake and fast systemic clearance, which favour their application as effective vehicles for radiotherapy. In addition aptamers can be labeled with different radioactive isotopes. The aim of this work was select aptamers binding to the CEA tumor marker. The aptamers are obtained through by SELEX, in which aptamers are selected from a library of random sequences of synthetic DNA by repetitive binding of the oligonucleotides to target molecule (CEA). Analyses of the secondary structure of the aptamers were determined using the m fold toll. Three aptamers were selected to binding assay with target cells. These aptamers were confirmed to have affinity and specific binding for T84 cell line (target cell), showed by confocal imaging. We are currently studying the potential efficacy of these aptamers as targeted radiopharmaceuticals, for use as imaging agents or therapeutic applications. The development of aptamers specific to CEA open new perspectives for colorectal cancer diagnosis and treatment. Acknowledgments: This investigation was supported by the Centro de Desenvolvimento da

  12. An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492

    International Nuclear Information System (INIS)

    Brunel, Guy; Denis, Dominique; Boulet, Alain

    2013-01-01

    The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m 2 allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the visitors

  13. Apports et limites des programmes de recherche aux sciences de gestion

    OpenAIRE

    Jeanjean, Thomas; Tixier, Julie

    2001-01-01

    Dans cet article, nous étudions la méthodologie des programmes de recherche de Lakatos (1978) et ses apports aux sciences sociales et en particulier à la recherche en gestion. Notre objectif est triple. Il s'agit d’abord de préciser la nature des programmes de recherche, de les critiquer et de les situer par rapport aux thèses défendues par Popper, Feyerabend et Kuhn. Par ailleurs, nous étudions la transférabilité de la méthodologie de Lakatos aux sciences sociales. Enfin, nous analysons l’in...

  14. DREAM IT, un programme de recherche aux fins d'autonomisation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    DREAM IT, un programme de recherche aux fins d'autonomisation de tous les Mongols grâce aux TIC ... Plus précisément, la recherche visera l'amélioration de la prestation des services d'éducation dans les régions éloignées grâce aux téléphones mobiles, à la télévision et à Internet; la conception d'un système ...

  15. Values of serum TSGF, CA125 and CEA determination in early diagnosis of ovarian cancer

    International Nuclear Information System (INIS)

    He Jiang; Zhou Yu; Yu Wuzhong; Chou Donghui; Zhou Ying; Zhang Yang; Guo Yong; Wang Yongsheng

    2005-01-01

    To investigate levels of TSGF,CA125 and CEA as a panel for early diagnosis of overian cancer, the levels of three tumor markers(TSGF,CA125 and CEA) in serum were determined in 85 patients with ovarian cancer, 54 patients with benign tumor and 76 healthy control. The results showed that the levels of three tumor markers in ovarian cancer patients were significantly higher than those in benign tumor patients and controls(P<0.05). Combined detection of the three markers may greatly improve the diagnostic accuracy of overian cancer. (authors)

  16. Diagnostic value of CEA and CYFRA 21-1 tumor markers in primary lung cancer.

    Science.gov (United States)

    Okamura, Kyoko; Takayama, Koichi; Izumi, Miiru; Harada, Taishi; Furuyama, Kazuto; Nakanishi, Yoichi

    2013-04-01

    Lung cancer is sometimes difficult to differentiate from benign lung diseases expressing nodular shadow in imaging study. We assessed the diagnostic value of two commonly used tumor markers in distinguishing primary lung cancer from benign lung disease. The serum levels of carcinoembryonic antigen (CEA) and cytokeratin 19 fragments (CYFRA 21-1) were retrospectively analyzed in 655 lung cancer patients and 237 patients with benign lung disease. The standard cut-off levels of 3.2 ng/mL CEA and 3.5 ng/mL CYFRA 21-1 and twice these respective levels (6.4 ng/mL and 7.0 ng/mL) were used. CEA and CYFRA 21-1 levels were elevated in 32% and 11% of benign lung disease patients, respectively. CEA sensitivity and specificity for lung cancer diagnosis was 69% and 68% respectively, while that for CYFRA 21-1 was 43% and 89%, respectively. Thus, the combined value for the specificity of the two tumor markers was greater than either alone. Patients were grouped depending on their hospital status, and prevalence rates were determined. The prevalence rate of lung cancer in admitted patients was 51%, the prevalence rate of lung cancer in outpatients was 12%, and the prevalence rate of lung cancer identified during health check-ups was 0.1%. Positive predictive values (PPVs) were calculated using Bayes' theorem, and varied with the serum tumor marker and prevalence rate: PPVs of CEA [prevalence rate] were 69.2% [51%], 22.7% [12%], and 0.22% [0.1%], while PPVs of CYFRA 21-1 were 80.3% [51%], 34.8% [12%], and 0.39% [0.1%]. However, PPVs for lung cancer diagnosis at a prevalence rate of 51% were 87.3% or higher when the patient exhibited positive CEA and CYFRA 21-1, or CEA or CYFRA 21-1 levels twice the standard cut-off. Our results indicate that CEA and CYFRA 21-1 are reliable serum tumor markers for the diagnosis of lung cancer in addition to CT scans when combined or used individually at twice the standard cut-off level in high prevalence rate groups. The prevalence rate should

  17. The CEA and the alternative energies. Press tour 25 and 26 november 1999

    International Nuclear Information System (INIS)

    Carola, G.; Ngo, Ch.; Mermilliod, N.; Serre-Combe, P.; Sanglan, P.; De La Graviere, M.; Dieudonne, O.; Malbranche, Ph.

    1999-11-01

    In the framework of the public information on the CEA center of Cadarache and Grenoble, a presentation of the researches concerning the alternative energies is proposed. The Cea is commissioned by the Public Authorities, to keep the nuclear option open and for the long-dated, to develop renewable energies. In this domain researches on fuel cells and photovoltaic solar energy are performed. The principle and the applications of the fuel cell and the photovoltaic are recalled to introduce the research programs and the partners. (A.L.B.)

  18. General review of multispectral cooled IR development at CEA-Leti, France

    Science.gov (United States)

    Boulard, F.; Marmonier, F.; Grangier, C.; Adelmini, L.; Gravrand, O.; Ballet, P.; Baudry, X.; Baylet, J.; Badano, G.; Espiau de Lamaestre, R.; Bisotto, S.

    2017-02-01

    Multicolor detection capabilities, which bring information on the thermal and chemical composition of the scene, are desirable for advanced infrared (IR) imaging systems. This communication reviews intra and multiband solutions developed at CEA-Leti, from dual-band molecular beam epitaxy grown Mercury Cadmium Telluride (MCT) photodiodes to plasmon-enhanced multicolor IR detectors and backside pixelated filters. Spectral responses, quantum efficiency and detector noise performances, pros and cons regarding global system are discussed in regards to technology maturity, pixel pitch reduction, and affordability. From MWIR-LWIR large band to intra MWIR or LWIR bands peaked detection, results underline the full possibility developed at CEA-Leti.

  19. Changes in the legal status of the Commissariat a l'energie atomique (Cea)

    International Nuclear Information System (INIS)

    Grammatico-Vidal, L.

    2009-01-01

    The Cea a public research institution was re-classified among the energy research establishments (11 december 2008). The Cea, as the result of exceptional circumstances and complex activities, is today entering into a new era and must confront many national and supranational challenges. It is preparing, in effect, for a future nuclear industry (safer, less polluting, non-proliferating and more economical) and is conducting research into other energy solutions within the framework of sustainable development and limited greenhouse gas effects (hydrogen technology, fusion, alternative energy technologies). It also has another goal, to make technological research available to industry, not only by developing micro and nano-technologies or even to contribute technology for the benefit of scientific knowledge of living creatures, matter, climate and the environment. The new classification of the Cea as a research establishment in the field of energy, a heading which includes three other entities (A.N.D.R.A., A.D.E.M.E. and I.F.P.), raises questions about its specialization and diversification. However, no substantive change was made to the drafting of the legislative provisions so it is possible to imagine that the Cea takes initiatives in other fields, at the instigation or with the approval of the government, a matter which is facilitated by its classification in the E.P.I.C. category (public establishment at industrial and commercial character). The Cea also represents France in international organisations in the nuclear sector, such as the OECD Nuclear energy agency (Nea), the International atomic energy agency (IAEA) and the European communities. It also participates in intergovernmental negotiations in the nuclear field and ensures any follow-up required with regard to any resulting agreements. today, the Cea plays a major role in the implementation of French nuclear policy with the aim of making available to countries wishing to develop nuclear energy, a framework

  20. Importance of low-level radioactive wastes in dismantling strategy in CEA (FRANCE)

    International Nuclear Information System (INIS)

    Lafaille, C.

    1991-01-01

    This paper describes the advance used in C.E.A. to realize dismantling operations in the best technical and economical conditions. Particularly, for low-level radioactive waste management CEA's advance defines, first, the final destination of dismantling materials: - recycling in public lands for level activity inferior to 1 Bq/g; directly or after transformation (melting, calcination, extrusion) - storage in a ground disposal, after compacting, encapsulation or drumming. Two examples are given: - Marcoule G2 - G3 reactor dismantling - Gaseous diffusion plants demolition (COGEMA Pierrelatte)

  1. The releases control and the environment survey of the Cea Centers

    International Nuclear Information System (INIS)

    2002-01-01

    The Cea sets the environment protection in the heart of its security policy, which is based on the mastership of risks resulting from the researches activities and installations development. This policy aims to reduce as small as possible compared with the technical and economical necessities, the impact of its activities on the human and the environment. This document, takes stock for the year 2002, of the liquid and gas radioactive effluents releases as also of the radioactivity level around the Cea Centers, by a systematic monitoring of the atmosphere, the waters, the vegetation and the milk. (A.L.B.)

  2. Protocolo de actuación ante la rosácea en la farmacia comunitaria

    Directory of Open Access Journals (Sweden)

    Espinosa Suances A

    2016-06-01

    Full Text Available La rosácea es una dermatosis facial inflamatoria, recidivante y crónica, que con frecuencia demanda consulta en la farmacia comunitaria. Orientado hacia la práctica clínica del farmacéutico comunitario, este artículo revisa y sintetiza los conceptos clásicos y los avances más recientes en la comprensión y el tratamiento de esta enfermedad cutánea. Finalmente, propone un protocolo para la asistencia de pacientes con rosácea en la farmacia comunitaria.

  3. The extraction behaviour of the Rose Bengal labelled with 131I in the presence of cationic surfactants

    International Nuclear Information System (INIS)

    Lengyel, J.; Krtil, J.; Kuban, V.

    1989-01-01

    The extraction behaviour of the Rose Bengal in the presence of not only Septonex, but also other cationic surfactants (cetyltrimethylammonium bromide, cetylpyridinium bromide) was studied. The extraction constants of the ion associates of the Rose Bengal with cationic surfactants were determined radiometrically with the aid of Rose Bengal labelled with 131 I. (author) 8 refs.; 1 tab

  4. 3 CFR 8337 - Proclamation 8337 of January 6, 2009. Establishment of the Rose Atoll Marine National Monument

    Science.gov (United States)

    2010-01-01

    ... of the Rose Atoll Marine National Monument 8337 Proclamation 8337 Presidential Documents Proclamations Proclamation 8337 of January 6, 2009 Proc. 8337 Establishment of the Rose Atoll Marine National... 130 nautical miles east-southeast of Pago Pago Harbor, American Samoa, lies Rose Atoll—the easternmost...

  5. 78 FR 12015 - Western Pacific Fisheries; Fishing in the Marianas Trench, Pacific Remote Islands, and Rose Atoll...

    Science.gov (United States)

    2013-02-21

    ... Islands, and Rose Atoll Marine National Monuments AGENCY: National Marine Fisheries Service (NMFS..., Pacific Remote Islands, and Rose Atoll Marine National Monuments. The proposed rule is intended to...). Proclamation 8337 of January 6, 2009, ``Establishment of the Rose Atoll Marine National Monument'' (74 FR 1577...

  6. 78 FR 7385 - Western Pacific Fisheries; Fishing in the Marianas Trench, Pacific Remote Islands, and Rose Atoll...

    Science.gov (United States)

    2013-02-01

    ...-BA98 Western Pacific Fisheries; Fishing in the Marianas Trench, Pacific Remote Islands, and Rose Atoll... Presidential proclamations that created the Marianas Trench, Pacific Remote Islands, and Rose Atoll Marine..., 2009). Proclamation 8337 of January 6, 2009, ``Establishment of the Rose Atoll Marine National Monument...

  7. 78 FR 32996 - Western Pacific Fisheries; Fishing in the Marianas Trench, Pacific Remote Islands, and Rose Atoll...

    Science.gov (United States)

    2013-06-03

    ... Islands, and Rose Atoll Marine National Monuments AGENCY: National Marine Fisheries Service (NMFS..., and Rose Atoll Marine National Monuments. The intent of this rule is to implement fishery management... Islands Monument, and Proclamation 8337 established the Rose Atoll Monument. The Proclamations define the...

  8. Isolation of linoleic and alpha-linolenic acids as COX-1 and -2 inhibitors in rose hip

    DEFF Research Database (Denmark)

    Jäger, Anna; Petersen, K N; Thomasen, G.

    2008-01-01

    Rose hip has previously shown clinical efficacy in the treatment of osteoarthritis, and organic solvent extracts of rose hip have showed inhibition of cyclooxygenase-1 and -2. A petroleum ether extract of rose hip was fractioned by VLC on silica; on a C-18 column and by HPLC. Each step was COX-1/...

  9. In vitro and in vivo comparison of binding of 99m-Tc-labeled anti-CEA MAb F33-104 with 99m-Tc-labeled anti-CEA MAb BW431/26

    International Nuclear Information System (INIS)

    Watanabe, N.; Gunma Univ. School of Medicine; Oriuchi, N.; Inoue, T.; Sugiyama, S.; Kuroki, M.; Matsuoka, Y.; Tanada, S.; Murata, H.; Sasaki, Y.

    1999-01-01

    Aim: The purpose of this study was to assess the potential for radioimmunodetection (RAID) of murine anti-carcinoembryonic antigen (CEA) monoclonal antibody (MAb) F33-104 labeled with technetium-99m (99m-Tc) by a reduction-mediated labeling method. Methods: The binding capacity of 99m-Tc-labeled anti-CEA MAb F33-104 with CEA by means of in vitro procedures such as immunoradiometric assay and cell binding assay and the biodistribution of 99m-Tc-labeled anti-CEA MAb F33-104 in normal nude mice and nude mice bearing human colon adenocarcinoma LS180 tumor were investigated and compared with 99m-Tc-labeled anti-CEA MAb BW431/26. Results: The in vitro binding rate of 99m-Tc-labeled anti-CEA MAb F33-104 with CEA in solution and attached to the cell membrane was significantly higher than 99m-Tc-labeled anti-CEA MAb BW431/261 (31.4 ± 0.95% vs. 11.9 ± 0.55% at 100 ng/mL of soluble CEA, 83.5 ± 2.84% vs. 54.0 ± 2.54% at 10 7 of LS 180 cells). In vivo, accumulation of 99m-Tc-labeled anti-CEA MAb F33-104 was higher at 18 h postinjection than 99m-Tc-labeled anti-CEA MAb BW431/26 (20.1 ± 3.50% ID/g vs. 14.4 ± 3.30% ID/g). 99m-Tc-activity in the kidneys of nude mice bearing tumor was higher at 18 h postinjection than at 3 h (12.8 ± 2.10% ID/g vs. 8.01 ± 2.40% ID/g of 99m-Tc-labeled anti-CEA MAb F33-104, 10.7 ± 1.70% ID/g vs. 8.10 ± 1.75% ID/g of 99m-Tc-labeled anti-CEA MAb BW431/26). Conclusion: 99m-Tc-labeled anti-CEA MAb F33-104 is a potential novel agent for RAID of recurrent colorectal cancer. (orig.) [de

  10. Use of a combination of CEA and tumor budding to identify high-risk patients with stage II colon cancer.

    Science.gov (United States)

    Du, Changzheng; Xue, Weicheng; Dou, Fangyuan; Peng, Yifan; Yao, Yunfeng; Zhao, Jun; Gu, Jin

    2017-07-24

    High-risk patients with stage II colon cancer may benefit from adjuvant chemotherapy, but identifying this patient population can be difficult. We assessed the prognosis value for predicting tumor progression in patients with stage II colon cancer, of a panel of 2 biomarkers for colon cancer: tumor budding and preoperative carcinoembryonic antigen (CEA). Consecutive patients (N = 134) with stage II colon cancer who underwent curative surgery from 2000 to 2007 were included. Multivariate analysis was used to evaluate the association of CEA and tumor budding grade with 5-year disease-free survival (DFS). The prognostic accuracy of CEA, tumor budding grade and the combination of both (CEA-budding panel) was determined. The study found that both CEA and tumor budding grade were associated with 5-year DFS. The prognostic accuracy for disease progression was higher for the CEA-budding panel (82.1%) than either CEA (70.9%) or tumor budding grade (72.4%) alone. The findings indicate that the combination of CEA levels and tumor budding grade has greater prognostic value for identifying patients with stage II colon cancer who are at high-risk for disease progression, than either marker alone.

  11. Sensitivity of CA 15-3, CEA and serum HER2 in the early detection of recurrence of breast cancer

    DEFF Research Database (Denmark)

    Eriksen, Ann Christina; Sørensen, Patricia Diana; Jacobsen, Erik Hugger

    2013-01-01

    The aim of this project was to investigate the sensitivity of CA 15-3, CEA and HER2 in the early diagnosis of metastatic breast cancer.......The aim of this project was to investigate the sensitivity of CA 15-3, CEA and HER2 in the early diagnosis of metastatic breast cancer....

  12. Elaboration of an alpha-numeric classification for file of matters of the documentation service of the CEA

    International Nuclear Information System (INIS)

    Braffort, P.

    1953-01-01

    We give the principles of a classification of matters to square basis, suiting the needs of the Service, of Documentation of the C.E.A. We present the detail of the categories in the order of the 'columns', likewise the big scientific subdivisions at the CEA. (authors) [fr

  13. CRED REA Coral Population Paramaters at Rose Atoll, American Samoa, 2006

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Belt transects along 1 or 2 consecutively-placed, 25m transect lines were surveyed as part of Rapid Ecological Assessments conducted at 11 sites at Rose Atoll in...

  14. CRED REA Coral Population Parameters at Rose Atoll, American Samoa, 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Belt transects along 2 consecutively-placed, 25m transect lines were surveyed as part of Rapid Ecological Assessments conducted at 12 sites at Rose Atoll in American...

  15. CRED REA Fish Team Stationary Point Count Surveys at Rose Atoll, 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Stationary Point Counts at 4 stations at each survey site were surveyed as part of Rapid Ecological Assessments conducted at 12 sites at Rose Atoll in American Samoa...

  16. Benthic Habitat Maps for Rose Atoll Marine National Monument in American Samoa from 2004 to 2010

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic habitat maps for Rose Atoll, American Samoa were derived from high resolution, multispectral satellite imagery for 2004, 2006, and 2010. The benthic habitat...

  17. EDTA-assisted synthesis of rose-like ZnO architectures

    Energy Technology Data Exchange (ETDEWEB)

    Li, Zhen [Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 201800 (China); Shanghai Applied Radiation Institute, Shanghai University, Shanghai 201800 (China); Fang, Yaoguo [Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 201800 (China); Peng, Liwei; Wu, Minghong [Shanghai Applied Radiation Institute, Shanghai University, Shanghai 201800 (China); Pan, Dengyu

    2010-10-15

    Rose-like ZnO nanostructures were prepared by a low-temperature solution route with assistance of ethylenediaminetetraacetic acid disodium (EDTA-2Na). The morphology of ZnO nanostructures was found to change from nanowire arrays to rose- and tower-like architectures with increasing the molar ratio of EDTA-2Na/Zn{sup 2+}. Also, the shape evolution of ZnO nanostructures with time was observed from flat nanosheets to wrinkled nanosheets and to rose-like nanostructures. EDTA-2Na as a strong complexing agent was found to play a key role in the shape evolution. Photoluminescence spectra show that the rose-like ZnO architectures have more defects than the nanowire arrays. (copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  18. The rose petal effect and the role of advancing water contact angles for drop confinement

    DEFF Research Database (Denmark)

    Mandsberg, Nikolaj Kofoed; Taboryski, Rafael J.

    2017-01-01

    We studied the role of advancing water contact angles on superhydrophobic surfaces that exhibited strong pinning effects as known in nature from rose petals. Textured surfaces were engineered in silicon by lithographical techniques. The textures were comprised of hexagonal microstructures...

  19. The survey and criterion of the compass rose in Chinese A-share market

    Science.gov (United States)

    Tian, Wenzhao; Wang, Yanxiang; Huo, Zhao; Li, Yilin

    2018-02-01

    The compass rose is one of the few "recurring patterns" found in financial markets. In this paper, the compass rose in Chinese A-share market is comprehensively investigated. It is newly discovered that among the 1331 A-shares, which had been listed for more than 15 years by the end of 2015, only about 20 show the compass rose. The outcome of the analysis shows that there exists a threshold of the ratio of the data points on main rays to all data points. Only when this ratio is above the threshold, the compass rose appears. The reasons why such a threshold exists, and its interrelationship with the data frequency and the tick/volatility ratio are analyzed.

  20. Georgia after the Rose Revolution: Geopolitical Predicament and Implications for U.S. Policy

    National Research Council Canada - National Science Library

    Cornell, Svante E

    2007-01-01

    .... Following the 2003 Rose Revolution in Georgia, relations with Russia turned sour as the new government proved both democratic and single-mindedly focused on rebuilding the Georgian state, resolving...

  1. Molecular characterization of Prunus necrotic ringspot virus isolated from rose in Brazil

    Directory of Open Access Journals (Sweden)

    Thor Vinícius Martins Fajardo

    2015-12-01

    Full Text Available ABSTRACT: There is no molecular characterization of Brazilian isolates of Prunus necrotic ringspot virus (PNRSV, except for those infecting peach. In this research, the causal agent of rose mosaic was determined and the movement (MP and coat (CP protein genes of a PNRSV isolate from rose were molecularly characterized for the first time in Brazil. The nucleotide and deduced amino acid sequences of MP and CP complete genes were aligned and compared with other isolates. Molecular analysis of the MP and CP nucleotide sequences of a Brazilian PNRSV isolate from rose and others from this same host showed highest identities of 96.7% and 98.6%, respectively, and Rose-Br isolate was classified in PV32 group.

  2. Spawning period and first maturity size of deep water rose shrimp ...

    African Journals Online (AJOL)

    Administrator

    2011-11-02

    Nov 2, 2011 ... index (GSI), ranged throughout the year, reaching its peak two times; first peak occurred in autumn ... The deep water rose shrimp, Parapenaeus longirostris .... macroscopic examination of the gonads (development and.

  3. Alien rose-ringed parakeets (Psittacula krameri) attack black rats (Rattus rattus) sometimes resulting in death

    OpenAIRE

    Hernández-Brito, Dailos; Luna, Amparo; Carrete, Martina; Tella, José Luis

    2014-01-01

    The rose-ring parakeet (Psittacula krameri) is one of the most successful invasive birds in its establishment worldwide. Studies addressing its potential impact on native biota mostly focus on birds and little is known about how these and other parakeet species interact with native mammals. Here, we report 21 aggressions of rose-ringed parakeets towards black rats (Rattus rattus) in urban parks in Seville (Southern Spain) and Tenerife (Canary Islands). Either solitary parakeets or, more often...

  4. Bird feeders may sustain feral Rose-ringed parakeets Psittacula krameri in temperate Europe

    OpenAIRE

    Clergeau , Philippe; Vergnes , Alan

    2011-01-01

    International audience; The Rose-ringed parakeet Psittacula krameri, a bird species of subtropical origin, has established feral populations in temperate Europe. We analysed the feeding habits of Rose-ringed parakeets near Paris, France, in order to assess if food provided by humans might contribute to the success of this invasive bird species. We considered 87 feeding events performed during 2002 -2007 and 247 feeding events performed during March -November 2008. We recorded the consumption ...

  5. Molecular characterization of Prunus necrotic ringspot virus isolated from rose in Brazil.

    OpenAIRE

    FAJARDO, T. V. M.; NASCIMENTO, M. B.; EIRAS, M.; NICKEL, O.; PIO-RIBEIRO, G.

    2016-01-01

    ABSTRACT: There is no molecular characterization of Brazilian isolates of Prunus necrotic ringspot virus (PNRSV), except for those infecting peach. In this research, the causal agent of rose mosaic was determined and the movement (MP) and coat (CP) protein genes of a PNRSV isolate from rose were molecularly characterized for the first time in Brazil. The nucleotide and deduced amino acid sequences of MP and CP complete genes were aligned and compared with other isolates. Molecular analysis of...

  6. Temperature effect on rose downy mildew development under environmental controlled conditions

    OpenAIRE

    Filgueira D., Juan José; Zambrano, Angélica

    2014-01-01

    The rose downy mildew disease, caused by Peronospora sparsa Berkeley, is one of the most important that affect rose crops in Colombia. To manage this disease, flower growers must deal with high-costs due to the excessive application of fungicides, but without good results. Studies on P. sparsa behavior have shown its narrow relationship with environmental conditions. In this study, the temperature effect was evaluated during the infection and sporulation of P. sparsa in Charlotte leaflets, a ...

  7. Marked bengal pink. A dynamic test using marking doses; its value in jaundice diagnosis; Rose bengale marque. Epreuve dynamique a doses tracantes; sa valeur dans le diagnostic des icteres

    Energy Technology Data Exchange (ETDEWEB)

    Kellershohn, C; Desgrez, A [Commissariat a l' Energie Atomique, Service Frederic Joliot, Service de Biologie, Saclay (France).Centre d' Etudes Nucleaires; Caroli, J [Hopital Saint Antoine, 75 - Paris (France); Delaloye, B [Lausanne (Switzerland)

    1961-07-01

    The authors do a historic calling back of the differential study of jaundices thanks to the semi logarithmic gradients of expurgation of bromine sulphone-phthalein and thanks to the time of appearance of this material in the bile collected by duodenal tubing. They sum up likewise the foreign works which lead to take the place of this test, the outside count at the level of the head, the liver, and the abdomen after intravenous injection of a running dose of marked Rose Bengal. They specify the technical conditions of this test and report an experience which corroborate its value, its accuracy and the interest of its using in the different types of jaundices (hepatitis and obstructive types). (author) [French] Les auteurs font un rappel historique de l'etude differentielle des icteres grace aux pentes semi-logarithmiques d'epuration de la bromesulfonephtaleine et grace au temps d'apparition de cette substance dans la bile recueillie par tubage duodenal. Ils resument egalement les travaux etrangers qui tendent a substituer a cette epreuve le comptage externe au niveau de la tete, du foie et de l'abdomen, apres injection intraveineuse d'une dose tracante de rose bengale marque. Ils precisent les conditions techniques de cette epreuve et rapportent une experience qui confirme sa valeur, son exactitude et l'interet de son utilisation dans les differentes categories d'icteres par hepatite et par obstruction. (auteur)

  8. Marked bengal pink. A dynamic test using marking doses; its value in jaundice diagnosis; Rose bengale marque. Epreuve dynamique a doses tracantes; sa valeur dans le diagnostic des icteres

    Energy Technology Data Exchange (ETDEWEB)

    Kellershohn, C.; Desgrez, A. [Commissariat a l' Energie Atomique, Service Frederic Joliot, Service de Biologie, Saclay (France).Centre d' Etudes Nucleaires; Caroli, J. [Hopital Saint Antoine, 75 - Paris (France); Delaloye, B. [Lausanne (Switzerland)

    1961-07-01

    The authors do a historic calling back of the differential study of jaundices thanks to the semi logarithmic gradients of expurgation of bromine sulphone-phthalein and thanks to the time of appearance of this material in the bile collected by duodenal tubing. They sum up likewise the foreign works which lead to take the place of this test, the outside count at the level of the head, the liver, and the abdomen after intravenous injection of a running dose of marked Rose Bengal. They specify the technical conditions of this test and report an experience which corroborate its value, its accuracy and the interest of its using in the different types of jaundices (hepatitis and obstructive types). (author) [French] Les auteurs font un rappel historique de l'etude differentielle des icteres grace aux pentes semi-logarithmiques d'epuration de la bromesulfonephtaleine et grace au temps d'apparition de cette substance dans la bile recueillie par tubage duodenal. Ils resument egalement les travaux etrangers qui tendent a substituer a cette epreuve le comptage externe au niveau de la tete, du foie et de l'abdomen, apres injection intraveineuse d'une dose tracante de rose bengale marque. Ils precisent les conditions techniques de cette epreuve et rapportent une experience qui confirme sa valeur, son exactitude et l'interet de son utilisation dans les differentes categories d'icteres par hepatite et par obstruction. (auteur)

  9. La fabrique des sciences des institutions aux pratiques

    CERN Document Server

    Benninghoff, Martin; Crettaz von Roten, Fabienne; Merz, Martina

    2006-01-01

    Aujourd'hui, les façons de produire, d'organiser, d'évaluer et d'utiliser les savoirs sont en profond débat. De plus en plus, l'Etat, la société civile et l'économie tentent d'influencer les activités des universités et des laboratoires de recherche. Ces développements mettent à l'épreuve tout à la fois les fondements des systèmes d'enseignement supérieur et de recherche, l'autonomie des institutions scientifiques, la définition des frontières des savoirs et l'acceptation des sciences. Dans des contextes suisses et européens, cet ouvrage s'intéresse aux manières dont les sciences et les technologies sont fabriquées, en analysant leurs institutions et les pratiques. A partir d'une approche relationnelle, les sciences et les technologies sont conçues comme des phénomènes profondément sociaux, culturels et politiques. Une telle démarche déstabilise les visions parfois idéalisées et stéréotypées de la construction des savoirs. Des études de cas détaillées décrivent des phénomè...

  10. Aux limites de la physique les paradoxes quantiques

    CERN Document Server

    Rothen, François

    2012-01-01

    Dans l’esprit des pères fondateurs de la science moderne, les phénomènes matériels se déroulent selon un schéma unique. La cause précède nécessairement l’effet, et la connaissance de l’effet permet de remonter à la cause. Sur la scène de la nature, le hasard n’occupe qu’une place congrue. On ne fait appel à lui que pour pallier notre ignorance. Dans les années 1920, la révolution quantique bouleverse ce cadre rigide. Elle accorde une place de choix au hasard, si malmené jusqu’alors, puis elle met en scène une constellation de phénomènes inexplicables aux yeux de la science dite classique. Après une courte introduction historique, l’auteur met ses lecteurs au contact de certains de ces phénomènes si contraires à l’intuition. Refusant l’aide du langage mathématique, il les convie à pénétrer dans un monde quantique qui déconcerte le novice avant de l’éblouir par sa nouveauté et sa cohérence. Un accent particulier est mis sur une application nouvelle de la physiqu...

  11. Introduction aux études sur le genre. - 2e éd. revue et augm.

    NARCIS (Netherlands)

    Bereni, L.; Chauvin, S.; Jaunait, A.; Revillard, A.

    2012-01-01

    Pourquoi offre-t-on des poupées aux filles et des voitures aux garçons ? Pourquoi les femmes gagnent-elles moins que les hommes ? Comment expliquer qu’elles effectuent les deux tiers du travail domestique ? Pourquoi est-ce si mal vu pour un homme d’être efféminé ? Le pouvoir est-il intrinsèquement

  12. Prognostic significance of preoperative serum CA125, CA19-9 and CEA in gastric carcinoma

    Science.gov (United States)

    Wang, Wei; Chen, Xiao-Long; Zhao, Shen-Yu; Xu, Yu-Hui; Zhang, Wei-Han; Liu, Kai; Chen, Xin-Zu; Yang, Kun; Zhang, Bo; Chen, Zhi-Xin; Chen, Jia-Ping; Zhou, Zong-Guang; Hu, Jian-Kun

    2016-01-01

    The prognostic significance of preoperative serum CA125, CA19-9 and CEA in gastric carcinoma (GC) has been widely reported and is still under debate. Here, we evaluated the prognostic significance of preoperative serum CA125, CA19-9 and CEA in patients with GC. 1692 patients with GC who underwent gastrectomy were divided into the training (from January 2005 to December 2011, n = 1024) and the validation (from January 2012 to December 2013, n = 668) cohorts. Positive groups of CA125 (> 13.72 U/ml), CA19-9 (> 23.36 U/ml) and CEA (> 4.28 ng/ml) were significantly associated with more advanced clinicopathological traits and worse outcomes than that of negative groups (all P tumor size (P tumor markers (NPTM) were more accurate in prognostic prediction than TNM stage alone. Our findings suggested that elevated preoperative serum CA125, CA19-9 and CEA were associated with more advanced clinicopathological traits and less favorable outcomes. In addition, CA125 as an independent prognostic factor should be further investigated. Nomogram based on NPTM could accurately predict the prognosis of GC patients. PMID:27097114

  13. Diagnostic significance of tumor markers CEA, CA50 and CA19-9 for colorectal cancer

    International Nuclear Information System (INIS)

    Chen Yumei; Huang Gang

    2005-01-01

    Objective: To investigate the expression and diagnostic significance of three serum tumor markers (CEA, CA50, CA19-9) in patients with colorectal cancer, with special emphasis on their combined assay. Methods: Serum CEA, CA19-9 levels (with chemiluminescence immunoassay) and CA50 levels (with immunoradiometric assay) were determined in 94 patients with colorectal cancer, 20 patients with benign colorectal disorders and 37 controls. Results: The expressions of the serum tumor markers were significantly higher in patients with colorectal cancer than those in patients with benign colorectal disorders and controls (P<0.05). There was no significant difference between the levels in the latter two groups. CEA assay had the highest sensitivity (57.4%) and specificity (85.9%). Combined assay of the three could enhance both the sensitivity (62.7%) and specificity (96.5%). The serum levels of the markers were significantly higher in patients with colonic cancer than those in patients with rectal cancer (P<0.05). The levels were positively correlated with the size of the growth and stage of the disease. Serum tumor marker levels were also significantly higher in patients with metastasis (regional/distant) than those in patients without metastasis (P<0.05). Conclusion: Determination of serum CEA, CA50 and CA19-9 levels had definite value for the diagnosis and assessment of the pathology as well as biologic behavior colorectal cancer. Combined assay of the three could enhance the diagnostic sensitivity and specificity. (authors)

  14. Meeting of Directors and Heads of Department from CEA-Saclay, France

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Left to right: Ph. Pradelles, M. Jacquemet and T. Taylor in discussion during the December visit of Directors and Heads of Department from the Saclay centre of the French atomic energy commission (CEA) to CERN's LHC magnet test facility. Looking on is Yves Lemoigne.

  15. Situation 2002: release monitoring and surveillance of environment of Cea centers

    International Nuclear Information System (INIS)

    2003-07-01

    This publication renders an account of the situation of the releases of liquid and gaseous radioactive effluents, for the year 2002, as well as the radioactivity levels measured in the vicinity of Cea centers through the systematic surveillance of atmosphere, waters, vegetation and milk. An analysis on five years allows to follow their evolution. (N.C.)

  16. Atom medicine. The history of health at work at the Cea and at the Cogema

    International Nuclear Information System (INIS)

    Lefebvre, V.

    2005-01-01

    This work aims to inform any people interested in the origins and the development of the medical surveillance of workers exposed to ionizing radiations by relating the history and experience of medical services and biological and medical analysis laboratories of the Cea and Cogema. (N.C.)

  17. Metastatic prostate cancer with elevated serum levels of CEA and CA19-9

    Directory of Open Access Journals (Sweden)

    Guang-Dar Juang

    2014-03-01

    Full Text Available Prostate-specific antigen (PSA is well known as a specific tumor marker for prostate cancer, but carcinoembryonic antigen (CEA- and carbohydrate antigen 19-9 (CA19-9-elevating adenocarcinomas originating in the prostate gland are rare. We report a case of metastatic adenocarcinoma of the prostate gland with a high serum level of CEA and CA19-9 in a 78-year-old man in whom prostate cancer (T3N1M1 had been diagnosed 2 years ago and who was treated with androgen deprivation therapy. He visited the emergency department because of a loss of appetite and abdominal pain. The serum CEA and CA19-9 levels were increased to 218.9 ng/mL (normal, <5 ng/mL and 212 ng/mL (normal, <27 ng/mL, respectively. The serum PSA level was slightly elevated (4.41 ng/mL. Computed tomography demonstrated multiple liver metastases, para-aortic lymph node enlargement, and lung metastases. A liver biopsy was performed and the specimen showed high-grade adenocarcinoma with focal positive staining for PSA. Despite chemotherapy with docetaxel, the patient died 3 months after treatment. Based on this case and a review of the literature, an aggressive variant of prostatic carcinoma with a high serum level of CEA and CA19-9 and a low PSA level was shown to progress rapidly with a poor prognosis.

  18. Plasma TIMP-1 and CEA as markers for detection of primary colorectal cancer

    DEFF Research Database (Denmark)

    Christensen, Ib Jarle; Brünner, Nils; Dowell, Barry

    2015-01-01

    endoscopy were prospectively included (N=1965). Baseline data and co-morbidity were recorded. The primary end-point was the detection of CRC. Plasma was obtained before endoscopy and TIMP-1 and CEA levels were determined using an automated analysis platform when all samples were collected. RESULTS: CRC...

  19. Iodine-131 labeled anti-CEA polyclonal antibody detection of gastrointestinal cancer

    International Nuclear Information System (INIS)

    Nabi, H.A.; Hinkle, G.H.; Olsen, J.O.; Haagensen, D.A.; Thurston, M.O.; Mojzisik, C.; Houchens, D.; Martin, E.W. Jr.

    1984-01-01

    To localize gastrointestinal tumor, 31 patients were injected with 1.7-2.1 mCi I-131 anti-CEA baboon polyclonal antibody. Whole body imaging at 48, 72, and occasionally 96 hrs was performed with a Signa Camera (Technicare) peaked at 364 keV with 20% window. Additional spot views were usually obtained. No subtraction methods were used. All patients had surgical and pathological confirmation of the nuclear medicine studies. Labeled antibody images were positive in 15 (8 recurrent or metastatic colorectal, 2 gastric, 1 pancreatic, 1 primary colon, and 1 breast metastatic to chest wall). In 1, antibody images were positive for metastatic deposits in para-aortic lymph nodes, but negative for primary rectal tumor. True negative images were observed in 6; false negative images in 9 (4 liver metastases, 2 rectal, 1 pancreatic, 1 mesenteric lymph node metastasis, 1 bone metastasis). In all cases, no correlation existed between preoperative CEA serum levels and imaging. I-131 labeled anti-CEA polyclonal antibody imaging proved highly efficient in detecting gastric cancer (2/2) and moderately efficient in detecting recurrent colorectal cancer (8/15). On the other hand, the I-131 labeled polyclonal anti-CEA antibody imaging was of limited value in detecting colon cancer (1/9), pancreatic cancer (1/4) and metastatic liver disease

  20. Environmental monitoring of the Cea Valduc centre; La surveillance environnementale du site du CEAValduc

    Energy Technology Data Exchange (ETDEWEB)

    Guetat, Ph. [CEA Valduc, Dir. adjoint, 21 - Is-sur-Tille (France); Jaskula, L. [CEA Valduc, service de protection contre les rayonnements, 21 - Is-sur-Tille (France)

    2010-06-15

    This paper describes the main features of the environmental control in the vicinity of the CEA Valduc centre, explains the site specific characteristics, the surveillance policy, and some historical elements about tritium atmospheric release. Some levels of activities are given, corresponding to an exposure level below 0.02% of natural irradiation. (author)