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Sample records for automatic stapling instrument

  1. Gastropexy with an automatic stapling instrument for the treatment of gastric dilatation and volvulus in 20 dogs

    OpenAIRE

    Belandria, Gerardo A.; Pavletic, Michael M.; Boulay, James P.; Penninck, Dominique G.; Schwarz, Leslie A.

    2009-01-01

    Surgical stapling equipment was used to create a gastropexy in 20 dogs undergoing emergency surgery for gastric dilatation and volvulus (GDV). The technique involved creation of a tunnel between the seromuscular layer and the submucosa of the pyloric antrum, and a matching tunnel beneath the right m. transversus abdominis. The arms of a gastrointestinal anastomosis stapling device were ...

  2. QXT-full Automatic Saccharify Instrument

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    QXT is a full automatic saccharify instrument of eight holes . The instrument use process control technology of micro-computer. It can realize automatic of saccharify full process correctly. Due to adapt control mode of high precision expert PID and digit automatic calibration technology of fill micro computer, not only ensure precision of linear raising temperature region (1 ℃ /min) and constant temperature region (temperature error ±0.2 ℃), but also overcome the disturbance

  3. Towards automatic musical instrument timbre recognition

    Science.gov (United States)

    Park, Tae Hong

    This dissertation is comprised of two parts---focus on issues concerning research and development of an artificial system for automatic musical instrument timbre recognition and musical compositions. The technical part of the essay includes a detailed record of developed and implemented algorithms for feature extraction and pattern recognition. A review of existing literature introducing historical aspects surrounding timbre research, problems associated with a number of timbre definitions, and highlights of selected research activities that have had significant impact in this field are also included. The developed timbre recognition system follows a bottom-up, data-driven model that includes a pre-processing module, feature extraction module, and a RBF/EBF (Radial/Elliptical Basis Function) neural network-based pattern recognition module. 829 monophonic samples from 12 instruments have been chosen from the Peter Siedlaczek library (Best Service) and other samples from the Internet and personal collections. Significant emphasis has been put on feature extraction development and testing to achieve robust and consistent feature vectors that are eventually passed to the neural network module. In order to avoid a garbage-in-garbage-out (GIGO) trap and improve generality, extra care was taken in designing and testing the developed algorithms using various dynamics, different playing techniques, and a variety of pitches for each instrument with inclusion of attack and steady-state portions of a signal. Most of the research and development was conducted in Matlab. The compositional part of the essay includes brief introductions to "A d'Ess Are ," "Aboji," "48 13 N, 16 20 O," and "pH-SQ." A general outline pertaining to the ideas and concepts behind the architectural designs of the pieces including formal structures, time structures, orchestration methods, and pitch structures are also presented.

  4. A Method for Modeling the Virtual Instrument Automatic Test System Based on the Petri Net

    Institute of Scientific and Technical Information of China (English)

    MA Min; CHEN Guang-ju

    2005-01-01

    Virtual instrument is playing the important role in automatic test system. This paper introduces a composition of a virtual instrument automatic test system and takes the VXIbus based a test software platform which is developed by CAT lab of the UESTC as an example. Then a method to model this system based on Petri net is proposed. Through this method, we can analyze the test task scheduling to prevent the deadlock or resources conflict. At last, this paper analyzes the feasibility of this method.

  5. On the Existence of an Optimal Control of Ship Automatic Steering Instruments

    Institute of Scientific and Technical Information of China (English)

    GAO Cunchen; GUO Jifeng

    2005-01-01

    The existence of linear quadratic optimal control of ship automatic steering instruments is studied. Firstly, the sufficient conditions for the quadratic integrability of the solutions of linear second order time-variant differential equations are developed. Secondly, the optimal control form of the ship automatic steering instrument is obtained by using the dynamic programming method, which guarantees a minimal ship sway range, during long-distance navigation, by using as little energy as possible. Finally, based on the above mentioned sufficient conditions, the conditions for the realization of optimal control are obtained, which provides a foundation for choosing the weighted coefficients for optimal control in engineering.

  6. A new automatic system for angular measurement and calibration in radiometric instruments.

    Science.gov (United States)

    Marquez, Jose Manuel Andujar; Bohórquez, Miguel Ángel Martínez; Garcia, Jonathan Medina; Nieto, Francisco Jose Aguilar

    2010-01-01

    This paper puts forward the design, construction and testing of a new automatic system for angular-response measurement and calibration in radiometric instruments. Its main characteristics include precision, speed, resolution, noise immunity, easy programming and operation. The developed system calculates the cosine error of the radiometer under test by means of a virtual instrument, from the measures it takes and through a mathematical procedure, thus allowing correcting the radiometer with the aim of preventing cosine error in its measurements.

  7. A New Automatic System for Angular Measurement and Calibration in Radiometric Instruments

    Directory of Open Access Journals (Sweden)

    Jose Manuel Andujar Marquez

    2010-04-01

    Full Text Available This paper puts forward the design, construction and testing of a new automatic system for angular-response measurement and calibration in radiometric instruments. Its main characteristics include precision, speed, resolution, noise immunity, easy programming and operation. The developed system calculates the cosine error of the radiometer under test by means of a virtual instrument, from the measures it takes and through a mathematical procedure, thus allowing correcting the radiometer with the aim of preventing cosine error in its measurements.

  8. Automatic localization of the da Vinci surgical instrument tips in 3-D transrectal ultrasound.

    Science.gov (United States)

    Mohareri, Omid; Ramezani, Mahdi; Adebar, Troy K; Abolmaesumi, Purang; Salcudean, Septimiu E

    2013-09-01

    Robot-assisted laparoscopic radical prostatectomy (RALRP) using the da Vinci surgical system is the current state-of-the-art treatment option for clinically confined prostate cancer. Given the limited field of view of the surgical site in RALRP, several groups have proposed the integration of transrectal ultrasound (TRUS) imaging in the surgical workflow to assist with accurate resection of the prostate and the sparing of the neurovascular bundles (NVBs). We previously introduced a robotic TRUS manipulator and a method for automatically tracking da Vinci surgical instruments with the TRUS imaging plane, in order to facilitate the integration of intraoperative TRUS in RALRP. Rapid and automatic registration of the kinematic frames of the da Vinci surgical system and the robotic TRUS probe manipulator is a critical component of the instrument tracking system. In this paper, we propose a fully automatic registration technique based on automatic 3-D TRUS localization of robot instrument tips pressed against the air-tissue boundary anterior to the prostate. The detection approach uses a multiscale filtering technique to identify and localize surgical instrument tips in the TRUS volume, and could also be used to detect other surface fiducials in 3-D ultrasound. Experiments have been performed using a tissue phantom and two ex vivo tissue samples to show the feasibility of the proposed methods. Also, an initial in vivo evaluation of the system has been carried out on a live anaesthetized dog with a da Vinci Si surgical system and a target registration error (defined as the root mean square distance of corresponding points after registration) of 2.68 mm has been achieved. Results show this method's accuracy and consistency for automatic registration of TRUS images to the da Vinci surgical system.

  9. Automatic Recognition Method for Optical Measuring Instruments Based on Machine Vision

    Institute of Scientific and Technical Information of China (English)

    SONG Le; LIN Yuchi; HAO Liguo

    2008-01-01

    Based on a comprehensive study of various algorithms, the automatic recognition of traditional ocular optical measuring instruments is realized. Taking a universal tools microscope (UTM) lens view image as an example, a 2-layer automatic recognition model for data reading is established after adopting a series of pre-processing algorithms. This model is an optimal combination of the correlation-based template matching method and a concurrent back propagation (BP) neural network. Multiple complementary feature extraction is used in generating the eigenvectors of the concurrent network. In order to improve fault-tolerance capacity, rotation invariant features based on Zernike moments are extracted from digit characters and a 4-dimensional group of the outline features is also obtained. Moreover, the operating time and reading accuracy can be adjusted dynamically by setting the threshold value. The experimental result indicates that the newly developed algorithm has optimal recognition precision and working speed. The average reading ratio can achieve 97.23%. The recognition method can automatically obtain the results of optical measuring instruments rapidly and stably without modifying their original structure, which meets the application requirements.

  10. Diversity-Oriented Peptide Stapling

    DEFF Research Database (Denmark)

    Tran, Thu Phuong; Larsen, Christian Ørnbøl; Røndbjerg, Tobias

    2017-01-01

    The introduction of macrocyclic constraints in peptides (peptide stapling) is an important tool within peptide medicinal chemistry for stabilising and pre-organising peptides in a desired conformation. In recent years, the copper-catalysed azide-alkyne cycloaddition (CuAAC) has emerged...... as a powerful method for peptide stapling. However, to date CuAAC stapling has not provided a simple method for obtaining peptides that are easily diversified further. In the present study, we report a new diversity-oriented peptide stapling (DOPS) methodology based on CuAAC chemistry. Stapling of peptides...... incorporating two azide-modified amino acids with 1,3,5-triethynylbenzene efficiently provides (i, i+7)- and (i, i+9)-stapled peptides with a single free alkyne positioned on the staple, that can be further conjugated or dimerised. A unique feature of the present method is that it provides easy access...

  11. Cardiovascular Automatic Feedback Control Instrument for Rescuing Critical Patients With Abnormal Blood Pressure

    Institute of Scientific and Technical Information of China (English)

    Ge Yuzhi; Wu Zhiting; Sheng Guotai; Li Gang

    2006-01-01

    Objectives Most medical instruments are designed for diagnosis purpose but very few for clinical treatment. Our research aim is to design and develop a cardiovascular automatic feedback control instrument (CAFCI) for rescuing the critical patients with abnormal blood pressure.Methods The CAFCI was designed on the basis of abundant clinical experiences and on successful mathematic modeling of our experimental data. The blood pressure, pulmonary capillary wedge pressure,and rates of heart beat were measured and inputted into a computer and drugs were chosen by a doctor through a user-friendly interface with the computer.The responses to medication were rapidly acquired and feed back to the computer by automatic detection system in a close-loop system. The data were refreshed every 7.5 sec in order to regulate the speed and dosage of the medications that were given. Results The experimental results with ten dogs showed that the CAFCI system took samples promptly and accurately so that the targeted blood pressure could be reached reliably based on our input parameters and our designing requirements. Conclusions Since the dependability and accuracy of the CAFCI system are much superior to that of the traditional method, its clinical application to rescue the critical patient warrants evaluation in the future.

  12. Automatic evaluation and data generation for analytical chemistry instrumental analysis exercises

    Directory of Open Access Journals (Sweden)

    Arsenio Muñoz de la Peña

    2014-01-01

    Full Text Available In general, laboratory activities are costly in terms of time, space, and money. As such, the ability to provide realistically simulated laboratory data that enables students to practice data analysis techniques as a complementary activity would be expected to reduce these costs while opening up very interesting possibilities. In the present work, a novel methodology is presented for design of analytical chemistry instrumental analysis exercises that can be automatically personalized for each student and the results evaluated immediately. The proposed system provides each student with a different set of experimental data generated randomly while satisfying a set of constraints, rather than using data obtained from actual laboratory work. This allows the instructor to provide students with a set of practical problems to complement their regular laboratory work along with the corresponding feedback provided by the system's automatic evaluation process. To this end, the Goodle Grading Management System (GMS, an innovative web-based educational tool for automating the collection and assessment of practical exercises for engineering and scientific courses, was developed. The proposed methodology takes full advantage of the Goodle GMS fusion code architecture. The design of a particular exercise is provided ad hoc by the instructor and requires basic Matlab knowledge. The system has been employed with satisfactory results in several university courses. To demonstrate the automatic evaluation process, three exercises are presented in detail. The first exercise involves a linear regression analysis of data and the calculation of the quality parameters of an instrumental analysis method. The second and third exercises address two different comparison tests, a comparison test of the mean and a t-paired test.

  13. An Automatic Instrument to Study the Spatial Scaling Behavior of Emissivity

    Directory of Open Access Journals (Sweden)

    Jun Xia

    2008-01-01

    Full Text Available In this paper, the design of an automatic instrument for measuring the spatialdistribution of land surface emissivity is presented, which makes the direct in situmeasurement of the spatial distribution of emissivity possible. The significance of this newinstrument lies in two aspects. One is that it helps to investigate the spatial scalingbehavior of emissivity and temperature; the other is that, the design of the instrumentprovides theoretical and practical foundations for the implement of measuring distributionof surface emissivity on airborne or spaceborne. To improve the accuracy of themeasurements, the emissivity measurement and its uncertainty are examined in a series ofcarefully designed experiments. The impact of the variation of target temperature and theenvironmental irradiance on the measurement of emissivity is analyzed as well. Inaddition, the ideal temperature difference between hot environment and cool environmentis obtained based on numerical simulations. Finally, the scaling behavior of surfaceemissivity caused by the heterogeneity of target is discussed.

  14. Semi-automatic system for UV images analysis of historical musical instruments

    Science.gov (United States)

    Dondi, Piercarlo; Invernizzi, Claudia; Licchelli, Maurizio; Lombardi, Luca; Malagodi, Marco; Rovetta, Tommaso

    2015-06-01

    The selection of representative areas to be analyzed is a common problem in the study of Cultural Heritage items. UV fluorescence photography is an extensively used technique to highlight specific surface features which cannot be observed in visible light (e.g. restored parts or treated with different materials), and it proves to be very effective in the study of historical musical instruments. In this work we propose a new semi-automatic solution for selecting areas with the same perceived color (a simple clue of similar materials) on UV photos, using a specifically designed interactive tool. The proposed method works in two steps: (i) users select a small rectangular area of the image; (ii) program automatically highlights all the areas that have the same color of the selected input. The identification is made by the analysis of the image in HSV color model, the most similar to the human perception. The achievable result is more accurate than a manual selection, because it can detect also points that users do not recognize as similar due to perception illusion. The application has been developed following the rules of usability, and Human Computer Interface has been improved after a series of tests performed by expert and non-expert users. All the experiments were performed on UV imagery of the Stradivari violins collection stored by "Museo del Violino" in Cremona.

  15. Automatic Detection Method of Behavior Change in Dam Monitor Instruments Cause by Earthquakes

    Directory of Open Access Journals (Sweden)

    Fernando Mucio Bando

    2016-02-01

    Full Text Available A hydroelectric power plant consists of a project of great relevance for the social and economic development of a country. However, this kind of construction demands extensive attention because the occurrence of unusual behavior on its structure may result in undesirable consequences. Seismic waves are some of the phenomena which demand attention of one in charge of a dam safety because once it happens can directly affect the structure behavior. The target of this work is to present a methodology to automatically detect which monitoring instruments have gone under any change in pattern and their measurements after the seism. The detection method proposed is based on a neuro/fuzzy/bayesian formulation which is divided in three steps. Firstly, a clustering of points in a time series is developed from a self-organizing Kohonen map. Afterwards a fuzzy set is built to transform the initial time series, with arbitrary distribution, into a new series with beta distribution probability and thus enable the detection of changing points through a Monte Carlo simulation via Markov chains. In order to demonstrate the efficiency of the proposal the methodology has been applied in time series generated by Itaipu power plant building structures measurement instruments, which showed little behavior change after the earthquake in Chile in 2010.

  16. The stapl Skeleton Framework

    KAUST Repository

    Zandifar, Mani

    2015-01-01

    © Springer International Publishing Switzerland 2015. This paper describes the stapl Skeleton Framework, a highlevel skeletal approach for parallel programming. This framework abstracts the underlying details of data distribution and parallelism from programmers and enables them to express parallel programs as a composition of existing elementary skeletons such as map, map-reduce, scan, zip, butterfly, allreduce, alltoall and user-defined custom skeletons. Skeletons in this framework are defined as parametric data flow graphs, and their compositions are defined in terms of data flow graph compositions. Defining the composition in this manner allows dependencies between skeletons to be defined in terms of point-to-point dependencies, avoiding unnecessary global synchronizations. To show the ease of composability and expressivity, we implemented the NAS Integer Sort (IS) and Embarrassingly Parallel (EP) benchmarks using skeletons and demonstrate comparable performance to the hand-optimized reference implementations. To demonstrate scalable performance, we show a transformation which enables applications written in terms of skeletons to run on more than 100,000 cores.

  17. Deriving aerosol properties from measurements of the Atmosphere-Surface Radiation Automatic Instrument (ASRAI)

    Science.gov (United States)

    Xu, Hua; Li, Donghui; Li, Zhengqiang; Zheng, Xiaobing; Li, Xin; Xie, Yisong; Liu, Enchao

    2015-10-01

    The Atmosphere-surface Radiation Automatic Instrument (ASRAI) is a newly developed hyper-spectral apparatus by Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences (AIOFM, CAS), measuring total spectral irradiance, diffuse spectral irradiance of atmosphere and reflected radiance of the land surface for the purpose of in-situ calibration. The instrument applies VIS-SWIR spectrum (0.4~1.0 μm) with an averaged spectral resolution of 0.004 μm. The goal of this paper is to describe a method of deriving both aerosol optical depth (AOD) and aerosol modes from irradiance measurements under free cloudy conditions. The total columnar amounts of water vapor and oxygen are first inferred from solar transmitted irradiance at strong absorption wavelength. The AOD together with total columnar amounts of ozone and nitrogen dioxide are determined by a nonlinear least distance fitting method. Moreover, it is able to infer aerosol modes from the spectral dependency of AOD because different aerosol modes have their inherent spectral extinction characteristics. With assumption that the real aerosol is an idea of "external mixing" of four basic components, dust-like, water-soluble, oceanic and soot, the percentage of volume concentration of each component can be retrieved. A spectrum matching technology based on Euclidean-distance method is adopted to find the most approximate combination of components. The volume concentration ratios of four basic components are in accordance with our prior knowledge of regional aerosol climatology. Another advantage is that the retrievals would facilitate the TOA simulation when applying 6S model for satellite calibration.

  18. The STAPL pList

    KAUST Repository

    Tanase, Gabriel

    2010-01-01

    We present the design and implementation of the stapl pList, a parallel container that has the properties of a sequential list, but allows for scalable concurrent access when used in a parallel program. The Standard Template Adaptive Parallel Library (stapl) is a parallel programming library that extends C++ with support for parallelism. stapl provides a collection of distributed data structures (pContainers) and parallel algorithms (pAlgorithms) and a generic methodology for extending them to provide customized functionality. stapl pContainers are thread-safe, concurrent objects, providing appropriate interfaces (e.g., views) that can be used by generic pAlgorithms. The pList provides stl equivalent methods, such as insert, erase, and splice, additional methods such as split, and efficient asynchronous (non-blocking) variants of some methods for improved parallel performance. We evaluate the performance of the stapl pList on an IBM Power 5 cluster and on a CRAY XT4 massively parallel processing system. Although lists are generally not considered good data structures for parallel processing, we show that pList methods and pAlgorithms (p-generate and p-partial-sum) operating on pLists provide good scalability on more than 103 processors and that pList compares favorably with other dynamic data structures such as the pVector. © 2010 Springer-Verlag.

  19. Automatic instrument for chemical processing to detect microorganism in biological samples by measuring light reactions

    Science.gov (United States)

    Kelbaugh, B. N.; Picciolo, G. L.; Chappelle, E. W.; Colburn, M. E. (Inventor)

    1973-01-01

    An automated apparatus is reported for sequentially assaying urine samples for the presence of bacterial adenosine triphosphate (ATP) that comprises a rotary table which carries a plurality of sample containing vials and automatically dispenses fluid reagents into the vials preparatory to injecting a light producing luciferase-luciferin mixture into the samples. The device automatically measures the light produced in each urine sample by a bioluminescence reaction of the free bacterial adenosine triphosphate with the luciferase-luciferin mixture. The light measured is proportional to the concentration of bacterial adenosine triphosphate which, in turn, is proportional to the number of bacteria present in the respective urine sample.

  20. The STAPL pView

    KAUST Repository

    Buss, Antal

    2011-01-01

    The Standard Template Adaptive Parallel Library (STAPL) is a C++ parallel programming library that provides a collection of distributed data structures (pContainers) and parallel algorithms (pAlgorithms) and a generic methodology for extending them to provide customized functionality. STAPL algorithms are written in terms of pViews, which provide a generic access interface to pContainer data by abstracting common data structure concepts. Briefly, pViews allow the same pContainer to present multiple interfaces, e.g., enabling the same pMatrix to be \\'viewed\\' (or used) as a row-major or column-major matrix, or even as a vector. In this paper, we describe the stapl pView concept and its properties. pViews generalize the iterator concept and enable parallelism by providing random access to, and an ADT for, collections of elements. We illustrate how pViews provide support for managing the tradeoff between expressivity and performance and examine the performance overhead incurred when using pViews. © 2011 Springer-Verlag Berlin Heidelberg.

  1. [Automatic tracking of cleaned dental instruments by means of the RFID technique].

    Science.gov (United States)

    Krejci, Ivo; Ney, Hervé; Bonny, Diane; Bréhier, Céline; Massa, Nicole; Negrin, Nadège; Bovet, Marc

    2013-01-01

    For dental care professionals, the availability and cleanliness of reusable instruments is of major importance. In order to guarantee a proper reprocessing (cleaning, sterilization) of each instrument and ensure optimum safety for the patients, a single instrument traceability solution can be implemented. The RFID (Radio Frequency Identification) technology is the only approach that can provide a fully automated identification of instruments, and a precise monitoring throughout the reprocessing cycle. It consists in integrating a miniature electronic component (RFID tag) to each instrument able to communicate with a transmitter located at a relatively close distance and capable of uniquely identifying each element in any given container, even when closed. In 2011, a pilot project was implemented in collaboration with the Division of Dentistry (SMD) of the University of Geneva and the central sterilization of the Geneva University Hospitals (HUG). This project has demonstrated the applicability and usefulness of RFID technology for tracking reusable dental instruments. In particular, the time saved by the operators and the massive risk reduction when compared to the possible errors during the process of manual identification are two major elements that justify the implementation of an RFID-based instrument traceability solution.

  2. Is STAPLE algorithm confident to assess segmentation methods in PET imaging?

    Science.gov (United States)

    Dewalle-Vignion, Anne-Sophie; Betrouni, Nacim; Baillet, Clio; Vermandel, Maximilien

    2015-12-01

    Accurate tumor segmentation in [18F]-fluorodeoxyglucose positron emission tomography is crucial for tumor response assessment and target volume definition in radiation therapy. Evaluation of segmentation methods from clinical data without ground truth is usually based on physicians’ manual delineations. In this context, the simultaneous truth and performance level estimation (STAPLE) algorithm could be useful to manage the multi-observers variability. In this paper, we evaluated how this algorithm could accurately estimate the ground truth in PET imaging. Complete evaluation study using different criteria was performed on simulated data. The STAPLE algorithm was applied to manual and automatic segmentation results. A specific configuration of the implementation provided by the Computational Radiology Laboratory was used. Consensus obtained by the STAPLE algorithm from manual delineations appeared to be more accurate than manual delineations themselves (80% of overlap). An improvement of the accuracy was also observed when applying the STAPLE algorithm to automatic segmentations results. The STAPLE algorithm, with the configuration used in this paper, is more appropriate than manual delineations alone or automatic segmentations results alone to estimate the ground truth in PET imaging. Therefore, it might be preferred to assess the accuracy of tumor segmentation methods in PET imaging.

  3. Generation of a reference radiation pattern of string instruments using automatic excitation and acoustic centering.

    Science.gov (United States)

    Shabtai, Noam R; Behler, Gottfried; Vorländer, Michael

    2015-11-01

    Radiation patterns of musical instruments are important for the understanding of music perception in concert halls, and may be used to improve the plausibility of virtual acoustic systems. Many attempts have been performed to measure the spatial response of musical instruments using surrounding spherical microphone arrays with a limited number of microphones. This work presents a high-resolution spatial sampling of the radiation pattern of an electrically excited violin, and addresses technical problems that arise due to mechanical reasons of the excitation apparatus using acoustic centering.

  4. Integrating Chemistry Laboratory Instrumentation into the Industrial Internet: Building, Programming, and Experimenting with an Automatic Titrator

    Science.gov (United States)

    Famularo, Nicole; Kholod, Yana; Kosenkov, Dmytro

    2016-01-01

    This project is designed to improve physical chemistry and instrumental analysis laboratory courses for undergraduate students by employing as teaching tools novel technologies in electronics and data integration using the industrial Internet. The project carried out by upper-division undergraduates is described. Students are exposed to a complete…

  5. The STAPL Parallel Graph Library

    KAUST Repository

    Harshvardhan,

    2013-01-01

    This paper describes the stapl Parallel Graph Library, a high-level framework that abstracts the user from data-distribution and parallelism details and allows them to concentrate on parallel graph algorithm development. It includes a customizable distributed graph container and a collection of commonly used parallel graph algorithms. The library introduces pGraph pViews that separate algorithm design from the container implementation. It supports three graph processing algorithmic paradigms, level-synchronous, asynchronous and coarse-grained, and provides common graph algorithms based on them. Experimental results demonstrate improved scalability in performance and data size over existing graph libraries on more than 16,000 cores and on internet-scale graphs containing over 16 billion vertices and 250 billion edges. © Springer-Verlag Berlin Heidelberg 2013.

  6. Instrumentation

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Journal Scope:Instrumentation is a high quality open access peer reviewed research journal.Authors are solicited to contribute to these journals by submitting articles that illustrate most up-to-date research results,projects,surveying works and industrial experiences that describe significant advances in the instrumental science.The mission of the Instrumentation is

  7. Instrumentation

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Journal Scope:Instrumentation is a high quality open access peer reviewed research journal.Authors are solicited to contribute to these journals by submitting articles that illustrate most up-to-date research results,projects,surveying works and industrial experiences that describe significant advances in the instrumental science.The mission of the Instrumentation is to provide a platform for the researchers,academicians,

  8. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2001-04-01

    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor.

  9. Research on the Design of Automatic Instrument in Chemical Industry%化工企业中自动化仪表的设计探究

    Institute of Scientific and Technical Information of China (English)

    鞠伟亚

    2015-01-01

    The production and operation environment of chemical enterprises is high pressure, high temperature, vacuum and other special environment, but in this special environment, automatic instrument plays a very important role. Therefore, we must do a good job in the design of chemical enterprise automation instrument; improve the stability and reliability of the automation instrument. Through the analysis of common chemical enterprise automatic instrument classification and instrument design selection, this paper describes the chemical enterprise automation instrument design technology, for reference.%化工企业的生产运营环境多是高压、高温、真空等特殊环境,而在这种特殊环境中,自动化仪表发挥着非常重要的作用.因此,必须做好化工企业的自动化仪表设计工作,提高自动化仪表的稳定性和可靠性.通过分析常见的化工企业自动化仪表分类和仪表设计选型,阐述了化工企业自动化仪表设计技术,以供参考.

  10. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2002-04-01

    SCK-CEN's R and D programme on instrumentation involves the development of advanced instrumentation systems for nuclear applications as well as the assessment of the performance of these instruments in a radiation environment. Particular emphasis is on the use of optical fibres as umbilincal links of a remote handling unit for use during maintanance of a fusion reacor, studies on the radiation hardening of plasma diagnostic systems; investigations on new instrumentation for the future MYRRHA accelerator driven system; space applications related to radiation-hardened lenses; the development of new approaches for dose, temperature and strain measurements; the assessment of radiation-hardened sensors and motors for remote handling tasks and studies of dose measurement systems including the use of optical fibres. Progress and achievements in these areas for 2001 are described.

  11. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2000-07-01

    SCK-CEN's research and development programme on instrumentation aims at evaluating the potentials of new instrumentation technologies under the severe constraints of a nuclear application. It focuses on the tolerance of sensors to high radiation doses, including optical fibre sensors, and on the related intelligent data processing needed to cope with the nuclear constraints. Main achievements in these domains in 1999 are summarised.

  12. Instruments

    Energy Technology Data Exchange (ETDEWEB)

    Buehrer, W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1996-12-31

    The present paper mediates a basic knowledge of the most commonly used experimental techniques. We discuss the principles and concepts necessary to understand what one is doing if one performs an experiment on a certain instrument. (author) 29 figs., 1 tab., refs.

  13. Instrumentation

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Journal Scope:Instrumentation is a high quality open access peer reviewed research journal,Authors are solicited to contribute to these journals by submitting articles that illustrate most up-to-date research results,projects,surveying works and industrial

  14. Review stapling peptides using cysteine crosslinking.

    Science.gov (United States)

    Fairlie, David P; Dantas de Araujo, Aline

    2016-11-01

    Stapled peptides are an emerging class of cyclic peptide molecules with enhanced biophysical properties such as conformational and proteolytic stability, cellular uptake and elevated binding affinity and specificity for their biological targets. Among the limited number of chemistries available for their synthesis, the cysteine-based stapling strategy has received considerable development in the last few years driven by facile access from cysteine-functionalized peptide precursors. Here we present some recent advances in peptide and protein stapling where the side-chains of cysteine residues are covalently connected with a range of different crosslinkers affording bisthioether macrocyclic peptides of varying topology and biophysical properties. © 2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 843-852, 2016.

  15. 医用手术吻(缝)合器的发展及术中应用%Research on development and surgical application of surgical stapling and stitching instrument

    Institute of Scientific and Technical Information of China (English)

    常林凤; 刘宝林

    2014-01-01

    There was almost one hundred years since surgical stapler invention to now. Using stapler (stitching instrument) in surgery has many advantages, such as stitching fast, easy to operating, few side effects and complications. It makes tumor excision surgery can’t be cut focus in past possible and improving the curative effect of the surgery. Surgical staplers also give difficult surgery and new technology strong supports. In the last ten years, for cheap price and rapid development of the technology level, domestic staplers’ market share is increasing year by year and breaking the foreign monopoly product. In open surgery, domestic stapler has progressively more than foreign brands. In endoscopy surgery, domestic staplers also have a place. In current, surgical staplers are used more and more popular in the domestic tertiary medical institutions and becoming indispensable tools in many surgeries. Surgical staplers (stitching instrument) are broadly used in esophageal reconstruction, gastrointestinal tract reconstruction, endoscopic surgery in pulmonary bulla resection, uterus resection, pancreas resection, duodenum resection%医用吻(缝)合器具有缝合快速、操作简便、副作用小及术后并发症少等优点,使得以往无法切除的肿瘤手术得以病灶切除,提高了手术的疗效,为高难度手术和新技术的开展提供了有力支撑。近年来,国产医用手术缝(吻)合器以其低廉的价格和快速发展的工艺技术水平在市场占有率上逐年提高,在开放式手术的应用中已逐步超过国外品牌,在腔镜手术中,国产吻合器也争得一席之地。目前,吻(缝)合器在国内三级医疗机构中应用逐渐普及,广泛应用于食管、胃肠道重建,在内镜手术中完成肺大泡切除、脾脏、子宫、胰腺及十二指肠等部位手术。

  16. 77 FR 60720 - Certain Polyester Staple Fiber From China

    Science.gov (United States)

    2012-10-04

    ... COMMISSION Certain Polyester Staple Fiber From China Determination On the basis of the record \\1\\ developed... antidumping duty order on certain polyester staple fiber from China would be likely to lead to continuation or... USITC Publication 4351 (September 2012), entitled Certain Polyester Staple Fiber from...

  17. 26 CFR 301.269B-1 - Stapled foreign corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Stapled foreign corporations. 301.269B-1....269B-1 Stapled foreign corporations. In accordance with section 269B(a)(1), a stapled foreign corporation is subject to the same taxes that apply to a domestic corporation under Title 26 of the...

  18. SKIN STAPLED OR SUTURED: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Veerendra Kumar

    2015-01-01

    Full Text Available BACKGROUND: The choice of wound closure after a surgical procedure has been a surgeon’s dilemma . The concerns have been as to how fast , uneventful , less painful , with minimal complications and comfortable will the patient’s recovery be. A well - known technology is surgical staples which are easier to use , less time consuming and a needle free method o f wound closure. OBJECTIVE: To compare skin staples with non - absorbable skin suture for skin closure in surgical laparotomy procedures for the following character : wound infection , dehiscence , cosmesis and postoperative pain . METHODS: This is a comparative study conducted on 100 patients divided in two groups randomly at Bapuji Hospital for cases undergoing surgical laparotomy procedures. Skin closure was done with 2 - 0 polyamide skin sutures in one group and skin closure was achieved with skin staples in th e other group. The outcome of wound was assessed on 3rd , 5th and 7th postoperative days using ASEPSIS score. Wound cosmesis was assessed on the 7th postoperative day and followed up at 1st month and 3rd month , using modified Hollander cosmesis scale. Postoperative pain was assessed using the visual analogue scale on the 1st , 3rd and 7th postoperative days. RESULTS : The mean wound ASPESIS scores on day 3 for skin staples and sutured group was 0.28 and 0.36 (p=0.7 respectively. The score on day 5 for staples and sutured group was 0.12 and 0.28 (p=0.4 respectively. The results in both the groups were the same , 0.08 on day 7(p=0. Wound cosmesis mean score assessment on day 7 for skin staples suturing group was 5.84 and 5.68 respectively (p=0.3. The mean score for cosmesis assessment at 1 month , and 3 rd month for skin staples and suturing group was 5.92 and 5.68 (p=0.1 and was 6.00 and 5.92 (p=0.36 respectively which was not satistically significant . The visual analogue scale score for postopera tive pain on 1st day , 3 rd and 7 th day for skin staples and suturing group 54

  19. Development of Automatic Measurement Instrument for Metallic Thermal Expansion Coefifcient%金属热胀系数自动测量仪的研制

    Institute of Scientific and Technical Information of China (English)

    刘存海; 刘芬芬

    2015-01-01

    An automatic measurement instrument for the metallic thermal expansion coefifcient is developed based on the combination of the traditional measuring and Michelson Interferometer. The length of the metal varies, the mirror moves tiny and the length difference of two lights when the metal is heated. The metallic thermal expansion coefifcient is measured automatically with a Michelson Interference fringes automatic counter for different temperature.%将迈克尔逊干涉仪的精确测量和传统金属线膨胀系数的测量方法相结合,研制一种金属热胀系数自动测量仪,被测金属样品被加热后会发生长度的变化,从带动镜面产生微小移动,进而引起迈克尔逊光路中两束光的光程差的改变,通过干涉条纹自动计数系统记录温度变化时干涉条纹的变化数量,以实现对金属热胀系数的自动测量。

  20. Preparation and Characterization of Nitinol Bone Staples for Cranio-Maxillofacial Surgery

    Science.gov (United States)

    Lekston, Z.; Stróż, D.; Jędrusik-Pawłowska, M.

    2012-12-01

    The aim of this work was to form NiTi and TiNiCo body temperature activated and superelastic staples for clinical joining of mandible and face bone fractures. The alloys were obtained by VIM technique. Hot and cold processing was applied to obtain wires of required diameters. The martensitic transformation was studied by DSC, XRD, and TEM. The shape memory effects were measured by a bend and free recovery ASTM F2082-06 test. The superelasticity was recorded in the tension stress-strain and by the three-point bending cycles in an instrument equipped with a Hottinger force transducer and LVDT. Excellent superelastic behavior of TiNiCo wires was obtained after cold working and annealing at 400-500 °C. The body temperature activated shape memory staples were applied for fixation of mandibular condyle fractures. In experiments on the skull models, fixation of the facial fractures by using shape memory and superelastic staples were compared. The superelastic staples were used in osteosynthesis of zygomatico-maxillo-orbital fractures.

  1. Full automatic fiducial marker detection on coil arrays for accurate instrumentation placement during MRI guided breast interventions

    Science.gov (United States)

    Filippatos, Konstantinos; Boehler, Tobias; Geisler, Benjamin; Zachmann, Harald; Twellmann, Thorsten

    2010-02-01

    With its high sensitivity, dynamic contrast-enhanced MR imaging (DCE-MRI) of the breast is today one of the first-line tools for early detection and diagnosis of breast cancer, particularly in the dense breast of young women. However, many relevant findings are very small or occult on targeted ultrasound images or mammography, so that MRI guided biopsy is the only option for a precise histological work-up [1]. State-of-the-art software tools for computer-aided diagnosis of breast cancer in DCE-MRI data offer also means for image-based planning of biopsy interventions. One step in the MRI guided biopsy workflow is the alignment of the patient position with the preoperative MR images. In these images, the location and orientation of the coil localization unit can be inferred from a number of fiducial markers, which for this purpose have to be manually or semi-automatically detected by the user. In this study, we propose a method for precise, full-automatic localization of fiducial markers, on which basis a virtual localization unit can be subsequently placed in the image volume for the purpose of determining the parameters for needle navigation. The method is based on adaptive thresholding for separating breast tissue from background followed by rigid registration of marker templates. In an evaluation of 25 clinical cases comprising 4 different commercial coil array models and 3 different MR imaging protocols, the method yielded a sensitivity of 0.96 at a false positive rate of 0.44 markers per case. The mean distance deviation between detected fiducial centers and ground truth information that was appointed from a radiologist was 0.94mm.

  2. Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein.

    Science.gov (United States)

    Joseph, Thomas Leonard; Lane, David; Verma, Chandra S

    2010-11-15

    Atomistic simulations of a set of stapled peptides derived from the transactivation domain of p53 (designed by Verdine & colleagues, JACS 2007 129:2456) and complexed to MDM2 reveal that the good binders are uniquely characterized by higher helicity and by extensive interactions between the hydrocarbon staples and the MDM2 surface; in contrast the poor binders have reduced helicity and their staples are mostly solvent exposed. Our studies also find that the best binders can also potentially inhibit MDMX with similar affinities, suggesting that such stapled peptides can be evolved for dual inhibition with therapeutic potential.

  3. 75 FR 64694 - Second Antidumping Duty Administrative Review of Certain Polyester Staple Fiber From the People's...

    Science.gov (United States)

    2010-10-20

    ... International Trade Administration Second Antidumping Duty Administrative Review of Certain Polyester Staple... the Preliminary Results of the second administrative review of certain polyester staple fiber (``PSF... Polyester Staple Fiber From the People's Republic of China: Notice of Preliminary Results and...

  4. Development of basic technology for instrumentation and control - Development of digital automatic supervisory limitation system and its design= validation

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jung In; Chung, Sung Wook; Koh, Won Seok [Kyungwon University, Sungman (Korea, Republic of); Suh, Duk Young; Cheon, Sei Young [Kyunghee University, Seoul (Korea, Republic of); Lee, Sang Kyung; Kim, Sung Hun [Seoul National University, Seoul (Korea, Republic of)

    1995-07-01

    A major objective of the project is to develop a digital automatic supervisory limitation system and validate its design for the next generation= nuclear power plant. The limitation system assures that the plant does not exceed the operating limits by regulation the plant operations through on-line monitoring the operating margins of the critical parameters. A new conceptual model of power maneuverability has been proposed for the design of the limitation system and for its validation. Also, the limitation system monitors overall operation processes throughout a nuclear power plant by implementing hierarchical communication networks. Based on the conceptual design in software of the 1 st year results, the detailed design of the limitation system has been performed during the 2 nd year with constructing a prototype digital system. The system consists of the software module for plant simulation and the hardware module for implementation of limitation system and the associated interfaces in hardware. The limitation algorithm were implemented into the microprocessor and the interfaces were realized through the I/O modules. Also, these modules are incorporated into the communication networks. The products of the project could be directly applicable to the following nuclear unit adopting the limitation system, providing the bumpless transition to the commercial design phase. And the prototype evaluation scheme will be very useful for the succeeding studies related to the digital nuclear I and C fields, such as fault-tolerance design methods, software verification and validation and response time execution of digital systems. 69 refs., 3 tabs., 44 figs. (author)

  5. 26 CFR 1.269B-1 - Stapled foreign corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Stapled foreign corporations. 1.269B-1 Section 1... (CONTINUED) INCOME TAXES Items Not Deductible § 1.269B-1 Stapled foreign corporations. (a) Treatment as a domestic corporation—(1) General rule. Except as otherwise provided, if a foreign corporation is a...

  6. Calibration Method of Nickel Water Quality On-line Automatic Monitoring Instrument%镍水质在线自动监测仪校准方法

    Institute of Scientific and Technical Information of China (English)

    肖克

    2016-01-01

    通过分析镍水质在线自动监测仪工作原理及结构,探讨其计量特性和校准方法。提出了校准项目和技术指标,示值误差:当镍的质量浓度c≤0.05 mg/L时为±0.01 mg/L,当0.05 mg/L<c≤0.2 mg/L时为±10%,当c>0.2 mg/L时为±5%;重复性不大于5%;稳定性不大于5%。对示值误差测量结果不确定度进行了评定,相对扩展不确定度为1.6%(k=2)。用所建校准方法对不同厂家的监测仪进行校准试验,示值误差、重复性、稳定性满足校准项目技术指标要求。该校准方法可以用于评价镍水质在线自动监测仪的性能。%The metrological characteristics and calibration method of the nickel water quality on-line automatic monitoring instrument were discussed on the basis of analysis of its working principle and structure. The calibration items and technical specifications were put forward. The indicating value error were±0.01 mg/L,±10% and±5% at the corresponding concentration of standard solutionc≤0.05 mg/L,0.05 mg/L0.2 mg/L, respectively. The repeatability was not more than 5% while the stability was not more than 5%. The measurement uncertainty of indicating value error was evaluated,and the relative expanded uncertainty was 1.6% (k=2). The established calibration method was applied to test monitoring instruments from different manufacturers. The results indicated that value error, repeatability and stability meet the requirement of technical specifications. This method can be used for the evaluation of the performance of nickel water quality on-line automatic monitoring instrument.

  7. Strength Distribution Analysis of Typical Staple Fibers

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The strength of staple fiber is an important property for yarns and fabrics. Usually there are variations in individual fiber strength, and this will affect the final strength of yarns and fabrics. In this study, Weibull distribution function is used to analyze the strength distribution of various staplefibers. The strengths of wool, silk, cotton, flax, acrylic, polyester, glass, aramid and carbon fiber are tested. It isfound that the strengths of cotton, polyester, glass, aramid and carbon fiber fit well with the two-factor Weibulldistribution, while those of wool and silk with the threefactir Weibull distribution. However, the strength distributionof flax cannot be expressed by either two- or three-factor Weibull distribution convincingly.

  8. Ecological Assessment of Autonomy in Instrumental Activities of Daily Living in Dementia Patients by the Means of an Automatic Video Monitoring System.

    Science.gov (United States)

    König, Alexandra; Crispim-Junior, Carlos Fernando; Covella, Alvaro Gomez Uria; Bremond, Francois; Derreumaux, Alexandre; Bensadoun, Gregory; David, Renaud; Verhey, Frans; Aalten, Pauline; Robert, Philippe

    2015-01-01

    Currently, the assessment of autonomy and functional ability involves clinical rating scales. However, scales are often limited in their ability to provide objective and sensitive information. By contrast, information and communication technologies may overcome these limitations by capturing more fully functional as well as cognitive disturbances associated with Alzheimer disease (AD). We investigated the quantitative assessment of autonomy in dementia patients based not only on gait analysis but also on the participant performance on instrumental activities of daily living (IADL) automatically recognized by a video event monitoring system (EMS). Three groups of participants (healthy controls, mild cognitive impairment, and AD patients) had to carry out a standardized scenario consisting of physical tasks (single and dual task) and several IADL such as preparing a pillbox or making a phone call while being recorded. After, video sensor data were processed by an EMS that automatically extracts kinematic parameters of the participants' gait and recognizes their carried out activities. These parameters were then used for the assessment of the participants' performance levels, here referred as autonomy. Autonomy assessment was approached as classification task using artificial intelligence methods that takes as input the parameters extracted by the EMS, here referred as behavioral profile. Activities were accurately recognized by the EMS with high precision. The most accurately recognized activities were "prepare medication" with 93% and "using phone" with 89% precision. The diagnostic group classifier obtained a precision of 73.46% when combining the analyses of physical tasks with IADL. In a further analysis, the created autonomy group classifier which obtained a precision of 83.67% when combining physical tasks and IADL. Results suggest that it is possible to quantitatively assess IADL functioning supported by an EMS and that even based on the extracted data the

  9. 对于JJG564-2002《重力式自动装料衡器》几个问题的认识%Recognizing of several questions about JJG564-2002 "automatic gravimetric filling weighing instrument"

    Institute of Scientific and Technical Information of China (English)

    沈立人

    2012-01-01

    JJG564-2002《重力式自动装料衡器》检定规程,是一个比较复杂的文件,它不同与非自动衡器的检定规程。它的适用范围、准确度等级和控制衡器的选择方法存在一些容易让人混淆的因素,在此交流一下个人的认识。%JJG564-2002 "automatic gravimetric filling weighing instrument" test rules, is a complex document, it is different from non-automatic weighing instrument test rules. Choosing method of scope, the level of accuracy and control instrument exists some confusing things, to exchange personal understanding in this article.

  10. 78 FR 51707 - Certain Polyester Staple Fiber From the Republic of Korea: Rescission of Antidumping Duty...

    Science.gov (United States)

    2013-08-21

    ... International Trade Administration Certain Polyester Staple Fiber From the Republic of Korea: Rescission of... administrative review of the antidumping duty order on certain polyester staple fiber (polyester staple fiber... antidumping duty order on polyester staple fiber from Korea for the period May 1, 2012, through April 30,...

  11. 76 FR 57955 - Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2011-09-19

    ... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty... administrative review of the antidumping duty order on certain polyester staple fiber from Taiwan. The period of... certain polyester staple fiber from Taiwan. See Certain Polyester Staple Fiber From Taiwan:...

  12. Cullin3-BTB interface: a novel target for stapled peptides.

    Directory of Open Access Journals (Sweden)

    Ivan de Paola

    Full Text Available Cullin3 (Cul3, a key factor of protein ubiquitination, is able to interact with dozens of different proteins containing a BTB (Bric-a-brac, Tramtrack and Broad Complex domain. We here targeted the Cul3-BTB interface by using the intriguing approach of stabilizing the α-helical conformation of Cul3-based peptides through the "stapling" with a hydrocarbon cross-linker. In particular, by combining theoretical and experimental techniques, we designed and characterized stapled Cul3-based peptides embedding the helix 2 of the protein (residues 49-68. Intriguingly, CD and NMR experiments demonstrate that these stapled peptides were able to adopt the helical structure that the fragment assumes in the parent protein. We also show that some of these peptides were able to bind to the BTB of the tetrameric KCTD11, a substrate adaptor involved in HDAC1 degradation, with high affinity (~ 300-600 nM. Cul3-derived staple peptides are also able to bind the BTB of the pentameric KCTD5. Interestingly, the affinity of these peptides is of the same order of magnitude of that reported for the interaction of full-length Cul3 with some BTB containing proteins. Moreover, present data indicate that stapling endows these peptides with an increased serum stability. Altogether, these findings indicate that the designed stapled peptides can efficiently mimic protein-protein interactions and are potentially able to modulate fundamental biological processes involving Cul3.

  13. A Buffer Stock Model to Ensure Price Stabilization and Availability of Seasonal Staple Food under Free Trade Considerations

    Directory of Open Access Journals (Sweden)

    Wahyudi Sutopo

    2012-07-01

    Full Text Available The price volatility and scarcity have been became a great problem in the distribution system of seasonal staple food produced by agro industry. It has salient supply disparity during the harvest and planting season. This condition could cause disadvantages to the stakeholders such as producer, wholesaler, consumer, and government. This paper proposes a buffer stock model under free trade considerations to substitute quantitative restrictions and tariffs by indirect market intervention instrument. The instrument was developed through buffer stock scheme in accordance with warehouse receipt system (WRS and collateral management system. The public service institution for staple food buffer stock (BLUPP is proposed as wholesaler’s competitor with main responsibility to ensure price stabilization and availability of staple food. Multi criteria decision making is formulated as single objective a mixed integer non linear programming (MINLP. The result shows that the proposed model can be applied to solve the distribution problem and can give more promising outcome than its counterpart, the direct market intervention instrument.

  14. A biomechanical research of growth control of spine by shape memory alloy staples.

    Science.gov (United States)

    Zhang, Wei; Zhang, Yonggang; Zheng, Guoquan; Zhang, Ruyi; Wang, Yan

    2013-01-01

    Shape memory alloy (SMA) staples in nickel titanium with shape memory effect are effective for spinal growth control. This study was designed to evaluate the biomechanical properties of the staples and observe the stability of the fixed segments spine after the staples were implanted. According to the vertical distance of the vertebrae, SMA staples of 5, 6.5, and 8 mm were designed. The recovery stress of 24 SMA staples in three groups was measured. The pullout strength of SMA staples and stainless steel staples in each functional spinal unit was measured. Each of the six fresh specimens was divided into three conditions: normal, single staple, and double staples. Under each condition, the angle and torque of spinal movements in six directions were tested. Results show that the differences in recovery stress and maximum pullout strength between groups were statistically significant. In left and right bending, flextion, and extention, the stability of spine was decreased in conditions of single staple and double staples. Biomechanical function of SMA staples was superior to stainless steel staple. SMA staples have the function of hemiepiphyseal compression and kyphosis and scoliosis model of thoracic vertebrae in goat could be successfully created by the fusionless technique.

  15. The two-fire, one-cartridge stapling method using a modified Endo-GIA.

    Science.gov (United States)

    Yamaguchi, A; Tsuchida, M

    1996-08-01

    The endoscopic stapler (Endo-GIA) was designed to divide tissue between two triple-stapled lines. The endoscopic surgeon frequently encounters situations where only stapling is required. Kirby described a staple closure method that uses a knifeless Endo-GIA cartridge. This method, although useful, has the problem of the modified Endo-GIA unit locking. Therefore, we devised a new technique for endoscopic stapling that involves two consecutive staplings using one cartridge without cutting. This method requires modification of the Endo-GIA system by removing the safety-lock system. In addition to enabling endoscopic stapling techniques without the risk of locking, the method can effect a significant cost savings.

  16. 非均匀光照下指针式仪表自动判读算法设计%AUTOMATIC INTERPRETATION ALGORITHM FOR POINTER INSTRUMENTS BASED ON NON-UNIFORM ILLUMINATION

    Institute of Scientific and Technical Information of China (English)

    刘迪; 毕笃彦; 李权合; 刘楠

    2013-01-01

    拟合人眼视觉机制提出了非均匀光照下指针仪表图像的预处理算法,在此基础上进一步设计了座舱指针式仪表自动判读算法。首先对仪表盘图像进行亮度均衡、二值化变换,再将指针细化,然后根据改进的Hough变换提取目标信息,确定座舱指针式仪表的读数。实验结果表明,该算法有效地解决了在非均匀光照情况下的飞机座舱指针式仪表自动判读,降低了判读误差。%the human visual mechanism , based on that we further design the automatic interpretation algorithm for cockpit pointer instruments .Firstly the algorithm conducts the lightness balance and binarisation transform on instruments panel images , and then makes the pointer needles thinning down;afterwards , it extracts the object information according to the modified Hough transformation and determines the readings of cockpit index instruments.Experimental results prove that the algorithm effectively solves the issue of automatic interpretation of cockpit pointer instruments in circumstance of non-uniform lightness , reduces the reading error .

  17. 77 FR 54562 - Certain Polyester Staple Fiber From the Republic of Korea: Rescission of Antidumping Duty...

    Science.gov (United States)

    2012-09-05

    ...] Certain Polyester Staple Fiber From the Republic of Korea: Rescission of Antidumping Duty Administrative...'') initiated an administrative review of the antidumping duty order on certain polyester staple fiber from...

  18. Buttressing staples with cholecyst-derived extracellular matrix (CEM) reinforces staple lines in an ex vivo peristaltic inflation model.

    LENUS (Irish Health Repository)

    Burugapalli, Krishna

    2008-11-01

    Staple line leakage and bleeding are the most common problems associated with the use of surgical staplers for gastrointestinal resection and anastomotic procedures. These complications can be reduced by reinforcing the staple lines with buttressing materials. The current study reports the potential use of cholecyst-derived extracellular matrix (CEM) in non-crosslinked (NCEM) and crosslinked (XCEM) forms, and compares their mechanical performance with clinically available buttress materials [small intestinal submucosa (SIS) and bovine pericardium (BP)] in an ex vivo small intestine model.

  19. Hydrocarbon-stapled lipopeptides exhibit selective antimicrobial activity.

    Science.gov (United States)

    Jenner, Zachary B; Crittenden, Christopher M; Gonzalez, Martín; Brodbelt, Jennifer S; Bruns, Kerry A

    2017-01-10

    Antimicrobial peptides (AMPs) occur widely in nature and have been studied for their therapeutic potential. AMPs are of interest due to the large number of possible chemical structural combinations using natural and unnatural amino acids, with varying effects on their biological activities. Using physicochemical properties from known naturally occurring amphipathic cationic AMPs, several hydrocarbon-stapled lipopeptides (HSLPs) were designed, synthesized, and tested for antimicrobial properties. Peptides were chemically modified by N-terminal acylation, C-terminal amidation, and some were hydrocarbon stapled by intramolecular olefin metathesis. The effects of peptide length, amphipathic character, and stapling on antimicrobial activity were tested against Escherichia coli, three species of Gram-positive bacteria (Staphylococcus aureus, Bacillus megaterium, and Enterococcus faecalis), and two strains of Candida albicans. Peptides were shown to disrupt liposomes of different phospholipid composition, as measured by leakage of a fluorescent compound from vesicles. Peptides with (S)-2-(4'-pentenyl)-alanine substituted for L-alanine in a reference peptide showed a marked increase in antimicrobial activity, hemolysis, and membrane disruption. Stapled peptides exhibited slightly higher antimicrobial potency; those with greatest hydrophobic character showed the greatest hemolysis and liposome leakage, but lower antimicrobial activity. The results support a model of HSLPs as membrane-disruptive AMPs with potent antimicrobial activity and relatively low hemolytic potential at biologically active peptide concentrations. This article is protected by copyright. All rights reserved.

  20. Ratooning and perennial staple crops in Malawi. A review

    NARCIS (Netherlands)

    Rogé, Paul; Snapp, Sieglinde; Kakwera, Mayamiko Nathaniel; Mungai, Leah; Jambo, Isaac; Peter, Brad

    2016-01-01

    The management of staple crops as perennials is a historic legacy and a present-day strategy in some regions of Sub-Saharan Africa, yet perenniality is rarely an agronomic subject. Farmers in Malawi cut annual crops, such as pigeonpea and sorghum, to extend production for more than one growing se

  1. Hemotype全自动血型分析系统在血型鉴定中的应用研究%Research on hemotype fully automatic blood grouping instrument for identification of blood groups

    Institute of Scientific and Technical Information of China (English)

    马晓军; 李海军; 李凌波

    2012-01-01

    目的 探讨全自动血型分析系统在ABO、RhD血型鉴定中的应用.方法 使用微板法自动血型分析系统,在一次性U形板上通过加样、离心、振荡、判读完成血型检测并发送报告.结果 8013份献血者ABO血型一次性准确定型率99.91%(8006/8013),7例正反定型不一致(含O细胞凝集),Rh(D)阴性4例.60例乳糜标本ABO血型正反定型一致.结论 全自动血型分析系统进行ABO正反定型及RhD血型检测更安全可靠,实验操作实现了标准化、自动化,检测结果可永久保存、便于查询.%Objective To evaluate fully automatic blood grouping instrument for identification of blood groups of ABO and RhD. Methods Using automatic detection system distribute red cell or plasma in microplate. After reacting with blood grouping reagent, observe the results and report on LAN (Local Area Network). Results The rates of first proper ABO grouping were 99. 91% (8006/8013).7 out of 8013 O-group donor blood samples showed agglutination in the reverse ABO typing. 1 sample was found to RhD negative. The rates of first proper ABO grouping were 100% ( 60/60) of chylemia. Conclusion Fully automatic blood grouping instrument for detecting blood groups of ABO and RhD is safer,Standardization and automatic of blood grouping experiments has been achieved. The results can be stored timelessly, and are convenient for query.

  2. 77 FR 25744 - Certain Polyester Staple Fiber From China; Institution of a Five-Year Review

    Science.gov (United States)

    2012-05-01

    ... COMMISSION Certain Polyester Staple Fiber From China; Institution of a Five- Year Review AGENCY: United...)) (the Act) to determine whether revocation of the antidumping duty order on certain polyester staple... order on imports of certain polyester staple fiber from China (72 FR 30545). The Commission...

  3. 77 FR 19619 - Certain Polyester Staple Fiber from the People's Republic of China: Extension of Preliminary...

    Science.gov (United States)

    2012-04-02

    ... International Trade Administration Certain Polyester Staple Fiber from the People's Republic of China: Extension... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... administrative review of the antidumping duty order on certain polyester staple fiber from the PRC.\\1\\...

  4. 75 FR 6352 - Certain Polyester Staple Fiber from the People's Republic of China: Extension of Preliminary...

    Science.gov (United States)

    2010-02-09

    ... International Trade Administration Certain Polyester Staple Fiber from the People's Republic of China: Extension... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... duty order on certain polyester staple fiber from the PRC. See Initiation of Antidumping...

  5. 76 FR 7532 - Certain Polyester Staple Fiber From the People's Republic of China: Extension of Preliminary...

    Science.gov (United States)

    2011-02-10

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Extension... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... duty order on certain polyester staple fiber from the PRC. See Initiation of Antidumping...

  6. 75 FR 30373 - Certain Polyester Staple Fiber From the People's Republic of China: Extension of Preliminary...

    Science.gov (United States)

    2010-06-01

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Extension... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... polyester staple fiber from the PRC. See Initiation of Antidumping and Countervailing Duty...

  7. 75 FR 39208 - Polyester Staple Fiber from Taiwan: Final Results of Changed-Circumstances Antidumping Duty...

    Science.gov (United States)

    2010-07-08

    ... International Trade Administration Polyester Staple Fiber from Taiwan: Final Results of Changed- Circumstances... antidumping duty order on polyester staple fiber from Taiwan. DATES: Effective Date: July 8, 2010. FOR FURTHER... changed-circumstances review of the antidumping duty order on polyester staple fiber from Taiwan...

  8. 77 FR 54561 - Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2012-09-05

    ...] Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review AGENCY... antidumping duty order on certain polyester staple fiber from Taiwan. The period of review is May 1, 2010... administrative review of the antidumping duty order on certain polyester staple fiber from Taiwan. See...

  9. 75 FR 4044 - Polyester Staple Fiber From Taiwan: Initiation and Preliminary Results of Changed-Circumstances...

    Science.gov (United States)

    2010-01-26

    ... International Trade Administration Polyester Staple Fiber From Taiwan: Initiation and Preliminary Results of... antidumping duty order on polyester staple fiber from Taiwan. We have preliminarily concluded that Far Eastern... the antidumping duty order on polyester staple fiber from Taiwan. Interested parties are invited...

  10. 75 FR 51442 - Polyester Staple Fiber from Taiwan: Rescission of Antidumping Duty Administrative Review in Part

    Science.gov (United States)

    2010-08-20

    ... International Trade Administration Polyester Staple Fiber from Taiwan: Rescission of Antidumping Duty... Commerce initiated an administrative review of the antidumping duty order on polyester staple fiber from...) initiated an ] administrative review of the antidumping duty order on polyester staple fiber from...

  11. 78 FR 17637 - Polyester Staple Fiber From Taiwan: Preliminary Results of Antidumping Duty Administrative Review...

    Science.gov (United States)

    2013-03-22

    ... International Trade Administration Polyester Staple Fiber From Taiwan: Preliminary Results of Antidumping Duty... the antidumping duty order on polyester staple fiber (PSF) from Taiwan. The period of review (POR) is... Antidumping Duty Administrative Review: Polyester Staple Fiber from Taiwan'' dated concurrently with...

  12. 77 FR 6783 - Certain Polyester Staple Fiber From the People's Republic of China: Extension of Preliminary...

    Science.gov (United States)

    2012-02-09

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Extension... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... administrative review of the antidumping duty order on certain polyester staple fiber from the PRC....

  13. 77 FR 62217 - Certain Polyester Staple Fiber From the People's Republic of China: Continuation of Antidumping...

    Science.gov (United States)

    2012-10-12

    ... Polyester Staple Fiber From the People's Republic of China: Continuation of Antidumping Duty Order AGENCY... certain polyester staple fiber from the People's Republic of China (``PRC'') would likely lead to a... the sunset review of the antidumping duty order on certain polyester staple fiber from the...

  14. 76 FR 58040 - Certain Polyester Staple Fiber From Korea and Taiwan

    Science.gov (United States)

    2011-09-19

    ... COMMISSION Certain Polyester Staple Fiber From Korea and Taiwan Determination On the basis of the record \\1... antidumping duty orders on certain polyester staple fiber from Korea and Taiwan would be likely to lead to...), entitled Certain Polyester Staple Fiber From Korea and Taiwan: Investigation Nos. 731-TA-825 and...

  15. 78 FR 38938 - Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review; 2011...

    Science.gov (United States)

    2013-06-28

    ... International Trade Administration Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty... results of the administrative review of the antidumping duty order on polyester staple fiber (PSF) from... Preliminary Results. None were received. \\1\\ See Polyester Staple Fiber From Taiwan: Preliminary Results...

  16. COMPARITIVE STUDY BETWEEN STAPLED HEMORRHOIDOPEXY AND CONVENTIONAL HEMORRHOIDECTOMY

    Directory of Open Access Journals (Sweden)

    Sudhir

    2014-03-01

    Full Text Available AIM: The aim of the study was to compare the results of stapled haemorroidopexy and open haemorrhoidectomy. METHODS: The study population consisted of 60 patients who were admitted with hemorrhoids to a Medical college hospital providing primary, secondary and tertiary care. Patients were allocated to both groups on random basis. The main outcome measures were, time taken for each surgical procedure, the intra- operative bleeding, Post- operative pain (visual analog scale, time taken for first defecation after operation, Duration of hospital stay and Time taken to return to work. Follow up was conducted for minimum period of 6 months. RESULTS: Stapled v/s conventional haemorrhoidectomy was associated with significantly reduced operating time (30.13±5.97 v/s 47.67±8.28 minutes; p= 0.001, Less blood loss during stapled v/s open haemorrhoidectomy (12.33 ml and 21.83 ml; p = 0.001, Reduced post-operative pain scores (Visual Anolog Score on the first 4 post-operative days (day 1: 4.63 v/s 5.70, day 2: 2.70 v/s 4.57, day 3: 1.83 v/s 3.70 and day 4: 1.2 v/s 3.10, where 0 indicates no pain and 10, maximum pain; p ≤ 0.001, Patients who underwent stapled haemorrhoidectomy passed stools earlier (22.10±3.75 hrs. and 26.03±3.77 hrs: p ≤ 0.001 than conventional group. Reduced number of hospital stay in stapled group (3.83±0.87 v/s 6.70±1.82 days: p≤0.001 compared to conventional group. Anal stricture noted in two patients in stapled group compared to 4 patients in open group. CONCLUSIONS: Stapled haemorroidopexy is associated with reduced operating time, less blood loss during surgery, reduced post-operative pain, less number of hospital admission days, early return to work. It is a safe and effective procedure for haemorrhoids; it may become a gold standard procedure for haemorrhoids in future

  17. 探讨炼油装置自动化检测仪表的安装与维护%Installation and maintenance of automatic detecting instruments in refining units

    Institute of Scientific and Technical Information of China (English)

    高嗣晟

    2015-01-01

    The automatic detecting instruments applied in refining units are introduced in this paper along with related installation processes. The potential faults are analyzed as well to provide maintenance measures.%本文首先对炼油装置自动化检测仪表进行简单的介绍,然后说明自动化检测仪表的安装过程,最后针对可能出现的事故进行分析,提出相应的维护措施.

  18. Jones' instrument technology

    CERN Document Server

    Jones, Ernest Beachcroft; Kingham, Edward G; Radnai, Rudolf

    1985-01-01

    Jones' Instrument Technology, Volume 5: Automatic Instruments and Measuring Systems deals with general trends in automatic instruments and measuring systems. Specific examples are provided to illustrate the principles of such devices. A brief review of a considerable number of standards is undertaken, with emphasis on the IEC625 Interface System. Other relevant standards are reviewed, including the interface and backplane bus standards. This volume is comprised of seven chapters and begins with a short introduction to the principles of automatic measurements, classification of measuring system

  19. A double stapled technique for oesophago-enteric anastomosis

    Institute of Scientific and Technical Information of China (English)

    A Kotru; A K John; E P Dewar

    2004-01-01

    AIM: Leakage from oesophageal anastomosis is associated with substantial morbidity and morality. This study presented a novel, safe and effective double stapled technique for oesophago-enteric anastomosis.METHODS: The data were obtained prospectively from hospital held clinical database. Thirty nine patients (26males, 13 females) underwent upper-gastrointestinal resection between 1996 and 2000 for carcinoma (n = 36),gastric lymphoma (n = 1), and benign pathology (n = 2).Double stapled oesophago-enteric anastomosis was performed in all cases.RESULTS: No anastomotic leak was reported. In cases of malignancy, the resected margins were free of neoplasm.Three deaths occurred, which were not related to anastomotic complications.CONCLUSION: Even though the reported study is an uncontrolled one, the technique described is reliable, and effective for oesophago-enteric anastomosis.

  20. Hydrocarbon stapled peptides as modulators of biological function.

    Science.gov (United States)

    Cromm, Philipp M; Spiegel, Jochen; Grossmann, Tom N

    2015-06-19

    Peptide-based drug discovery has experienced a significant upturn within the past decade since the introduction of chemical modifications and unnatural amino acids has allowed for overcoming some of the drawbacks associated with peptide therapeutics. Strengthened by such features, modified peptides become capable of occupying a niche that emerges between the two major classes of today's therapeutics-small molecules (5000 Da). Stabilized α-helices have proven particularly successful at impairing disease-relevant PPIs previously considered "undruggable." Among those, hydrocarbon stapled α-helical peptides have emerged as a novel class of potential peptide therapeutics. This review provides a comprehensive overview of the development and applications of hydrocarbon stapled peptides discussing the benefits and limitations of this technique.

  1. Three-corner wrist fusion using memory staples.

    Science.gov (United States)

    van Riet, Roger P; Bain, Gregory I

    2006-12-01

    Scapholunate dissociation with advanced collapse (SLAC), scaphoid nonunion advanced collapse (SNAC), and lunotriquetral advanced collapse (LTAC) of the carpus are challenging problems. Various treatment options have been described. We describe a technique of 3-corner wrist fusion, using memory staples. The scaphoid and triquetrum are resected, and the capitate is fused to the lunate. Articular cartilage is removed from the capitolunate joint, and the bones are shaped to conforming surfaces. Bone graft from the resected triquetrum and scaphoid is used to increase fusion rate and a dynamic compressive fixation force is applied due to the unique properties of the memory staples. The main advantages of this procedure include the following: retained anatomical articulation between the lunate and the lunate fossa on the radius, improved ulnar deviation due to the resection of the triquetrum, and an excellent fusion rate between the lunate and capitate due to the dynamic fixation, the conforming surfaces, and the use of autologous bone graft.

  2. Displaced anterior cruciate ligament avulsion fractures: Arthroscopic staple fixation

    Directory of Open Access Journals (Sweden)

    S R Sundararajan

    2011-01-01

    Full Text Available Background: Anterior cruciate ligament (ACL avulsion fracture is commonly associated with knee injuries and its management is controversial ranging from conservative treatment to arthroscopic fixation. The aim of our study was to assess the clinical and radiological results of arthroscopic staple fixation in the management of ACL avulsion fractures. Materials and Methods: Twenty-two patients (17 males and 5 females who underwent arthroscopic staple fixation for displaced ACL avulsion fractures were analysed. The mean age was 32.2 years (15-55 years with a mean followup of 21 months (6-36 months. All patients were assessed clinically by calculating their Lysholm and International Knee Documentation Committee (IKDC scores and the radiological union was assessed in the followup radiographs. Results: The mean Lysholm score was 95.4(83-100 and the mean IKDC score was 91.1(77-100 at the final followup. In 20 patients anterior drawer′s test was negative at the end of final followup while two patients had grade I laxity. Associated knee injuries were found in seven cases. The final outcome was not greatly influenced by the presence of associated injuries when treated simultaneously. At final followup all the patients were able to return to their pre-injury occupation Conclusion: Arthroscopic staple fixation is a safe and reliable method for producing clinical and radiological outcome in displaced ACL avulsion fractures.

  3. Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices.

    Science.gov (United States)

    Bird, Gregory H; Mazzola, Emanuele; Opoku-Nsiah, Kwadwo; Lammert, Margaret A; Godes, Marina; Neuberg, Donna S; Walensky, Loren D

    2016-10-01

    Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target protein interactions. While there is consensus that stapled peptides can be effective chemical tools for investigating protein regulation, their broader utility for therapeutic modulation of intracellular interactions remains an active area of study. In particular, the design principles for generating cell-permeable stapled peptides are empiric, yet consistent intracellular access is essential to in vivo application. Here, we used an unbiased statistical approach to determine which biophysical parameters dictate the uptake of stapled-peptide libraries. We found that staple placement at the amphipathic boundary combined with optimal hydrophobic and helical content are the key drivers of cellular uptake, whereas excess hydrophobicity and positive charge at isolated amino acid positions can trigger membrane lysis at elevated peptide dosing. Our results provide a design roadmap for maximizing the potential to generate cell-permeable stapled peptides with on-mechanism cellular activity.

  4. How I do it: the stapled ileal J pouch at restorative proctocolectomy.

    LENUS (Irish Health Repository)

    Martin, S T

    2011-12-01

    Ileal pouch-anal anastomosis (IPAA) following proctocolectomy is the preferred option for patients with medically refractory ulcerative colitis, indeterminate colitis, and familial adenomatous polyposis. However, it remains a procedure associated with morbidity and mortality. Pelvic sepsis, pouch fistulae, and anastomotic dehiscence predispose to pouch failure. We report our experience with an adaptation for the formation of the stapled ileal J pouch using the GIA™ 100 stapling device (Covidien, Mansfield, Massachusetts, USA). When creating the J pouch, we remove the bevelled plastic protector from the thin fork of the stapling device, allowing the staple line to be completed to the tip of the stapled efferent limb of the pouch, thereby minimizing potential blind ending in the efferent limb and injury to the transverse staple line.

  5. Automatic sequences

    CERN Document Server

    Haeseler, Friedrich

    2003-01-01

    Automatic sequences are sequences which are produced by a finite automaton. Although they are not random they may look as being random. They are complicated, in the sense of not being not ultimately periodic, they may look rather complicated, in the sense that it may not be easy to name the rule by which the sequence is generated, however there exists a rule which generates the sequence. The concept automatic sequences has special applications in algebra, number theory, finite automata and formal languages, combinatorics on words. The text deals with different aspects of automatic sequences, in particular:· a general introduction to automatic sequences· the basic (combinatorial) properties of automatic sequences· the algebraic approach to automatic sequences· geometric objects related to automatic sequences.

  6. Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction.

    Science.gov (United States)

    Lee, Jonghan Peter; Liu, Changdong; Li, Tianlu; Zhu, Guang; Li, Xuechen

    2015-07-01

    Six all-hydrocarbon-stapled Cdt1 MBD-derived peptides have been designed and synthesized to perturb the Cdt1-Mcm6 interaction, which is involved in DNA replication. Inconsistency between the helicity of the obtained peptidomimetics and their binding affinity has been observed. The helicity of 13-amino acid stapled peptides increased, while their binding to Mcm6 was decreased. On the other hand, the 30-amino acid stapled peptides exhibited decreased helicity but increased binding affinity.

  7. 基于电位法的水玻璃模数自动测定方法及仪器%Automatically determining modulus of sodium silicate and its instrument using potentiometry

    Institute of Scientific and Technical Information of China (English)

    刘蒙; 樊自田; 汪华方

    2011-01-01

    Method and instrument were introduced which could automatically determine the modulus of the sodium silicates based on potentiometry. The potential signals were collected by signal acquisition unit consisted of the antimony electrode and the temperature sensor.Micro-peristaltic pump was used to liquid fill and titrate solution.The STM32F103 microcontroller was exploited to control the titration process and carry out the data processing.Magnetic heating stirrer was applied to heat and mix the solution.The results show that the method and instrument can determine the modulus of the sodium silicate automatically,fleetly and accurately.%在遵循水玻璃模数测定原理的基础上,提出了一种基于电位法的水玻璃模数自动测定方法并设计了相关仪器,采用金属锑电极和温度传感器组成的信号采集单元采集到的电位信号取代传统的指示剂判断滴定终点;采用微型蠕动泵对待测溶液进行精确加液滴定代替手工加液滴定;采用STM32F103微控制器控制整个滴定过程并进行数据处理;采用磁力加热搅拌器对整个滴定过程进行加热搅拌.试验结果表明采用该方法及仪器可以自动、快速、准确测定水玻璃模数.

  8. Investigating peptide sequence variations for 'double-click' stapled p53 peptides.

    Science.gov (United States)

    Lau, Yu Heng; de Andrade, Peterson; Sköld, Niklas; McKenzie, Grahame J; Venkitaraman, Ashok R; Verma, Chandra; Lane, David P; Spring, David R

    2014-06-28

    Stapling peptides for inhibiting the p53/MDM2 interaction is a promising strategy for developing anti-cancer therapeutic leads. We evaluate double-click stapled peptides formed from p53-based diazidopeptides with different staple positions and azido amino acid side-chain lengths, determining the impact of these variations on MDM2 binding and cellular activity. We also demonstrate a K24R mutation, necessary for cellular activity in hydrocarbon-stapled p53 peptides, is not required for analogous 'double-click' peptides.

  9. Strengths,Problems,and Recommendations of Potato Staple Food Development in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    Weifang; FAN; Aiping; LAI; Guoquan; LU

    2015-01-01

    China launched the potato staple food strategy in 2015. The potato staple food strategy focuses on increasing potato consumption and promoting potato production through processing and use of potato staple food. This provides new opportunity for development of potato in Zhejiang Province. This paper analyzed development strengths and existing problems of the potato industry in Zhejiang Province. On this basis,it came up with pertinent recommendations for potato staple food development in Zhejiang Province,so as to guide consumption with nutrition,and guide production with consumption,to provide theoretical foundation for development of potato industry in Zhejiang Province.

  10. Modifications of the superstructure for the staple implant.

    Science.gov (United States)

    Guerra, L R; Larsen, H D; Finger, I M; Jaen, F

    1984-12-01

    Two techniques have been described to expedite fabrication and reduce the cost of prostheses made for staple implants. The techniques permit placement of a simulated transosseous pin within the master cast. At the time of denture placement in technique No. 1, the coping-bar attachment assembly is cemented (Fig. 12). In technique No. 2 the superstructure is placed over the transosteal pins and secured between the locknuts to maintain the base of the lower locknut 1.5 mm from the crest of the alveolar ridge (Fig. 13). Technique No. 2 permits removal of the superstructure as desired. Patients should be instructed in proper oral hygiene and denture care.

  11. 全自动酶联免疫检测仪与手工酶联免疫检测的比对评价%Comparative evaluation on detection of automatic enzyme instrument and manual enzyme detection

    Institute of Scientific and Technical Information of China (English)

    朱美芹; 王莉莉

    2014-01-01

    Objective To evaluate the consistency of the detection results of clinical specimen by the Tecan Freedom Evolyzer-200 fully automatic enzyme instrument and the BIO-RAD680 with manual operation .Methods The high concentration of hepatitis B surface antigen (HBsAg ) was adopted to understand the cross contamination situation of the instrument ,1 IU/mL HBsAg quality-control serum was adopted to detect the repeatability among holes and among plates .The random 50 clinical specimens were detected the 5 indexes of the liver function by this in-strument and BIO-RAD680 enzyme-labelling instrument with manual sample-adding ,the determination results were conducted the comparison .Results By testing ,the towing pollution of this enzyme immunoassay instrument was in the low level ,comparing the 5 indexes of hepatitis B in 50 clinical specimens measured by the manual operation ,the total coincidence rate was 96 .4% .Conclusion This instrument can meet the needs of the clinical trials .%目的:评价 Tecan Freedom Evolyzer-2200全自动酶联免疫仪与手工操作后BIO-RAD680酶标仪检测临床标本结果的一致性。方法用高浓度的乙型肝炎表面抗原(HBsAg )了解仪器的交叉污染情况,采用1 IU/mL的HBsAg质控血清检测其孔间重复性和板间重复性,随机抽取50份临床标本经该仪器和手工加样操作BIO-RAD680酶标仪测定乙型肝炎病毒5项指标,测定结果进行比对。结果经试验该酶联免疫仪器的拖带污染在低水平,与手工操作比对50个项目指标检测结果总的符合率达96.4%。结论该仪器可以满足临床实验需要。

  12. Carbohydrate Staple Food Modulates Gut Microbiota of Mongolians in China

    Science.gov (United States)

    Li, Jing; Hou, Qiangchuan; Zhang, Jiachao; Xu, Haiyan; Sun, Zhihong; Menghe, Bilige; Zhang, Heping

    2017-01-01

    Gut microbiota is a determining factor in human physiological functions and health. It is commonly accepted that diet has a major influence on the gut microbial community, however, the effects of diet is not fully understood. The typical Mongolian diet is characterized by high and frequent consumption of fermented dairy products and red meat, and low level of carbohydrates. In this study, the gut microbiota profile of 26 Mongolians whom consumed wheat, rice and oat as the sole carbohydrate staple food for a week each consecutively was determined. It was observed that changes in staple carbohydrate rapidly (within a week) altered gut microbial community structure and metabolic pathway of the subjects. Wheat and oat favored bifidobacteria (Bifidobacterium catenulatum, Bifodobacteriumbifidum, Bifidobacterium adolescentis); whereas rice suppressed bifidobacteria (Bifidobacterium longum, Bifidobacterium adolescentis) and wheat suppresses Lactobaciilus, Ruminococcus and Bacteroides. The study exhibited two gut microbial clustering patterns with the preference of fucosyllactose utilization linking to fucosidase genes (glycoside hydrolase family classifications: GH95 and GH29) encoded by Bifidobacterium, and xylan and arabinoxylan utilization linking to xylanase and arabinoxylanase genes encoded by Bacteroides. There was also a correlation between Lactobacillus ruminis and sialidase, as well as Butyrivibrio crossotus and xylanase/xylosidase. Meanwhile, a strong concordance was found between the gastrointestinal bacterial microbiome and the intestinal virome. Present research will contribute to understanding the impacts of the dietary carbohydrate on human gut microbiome, which will ultimately help understand relationships between dietary factor, microbial populations, and the health of global humans. PMID:28377764

  13. 自动变换量程的电化学仪设计%Design of Automatic Range-changing Electrochemistry Instrument

    Institute of Scientific and Technical Information of China (English)

    于航; 朱纪军

    2013-01-01

      为了解决电化学实验由于固定量程造成实验结果不正确或不精确的问题,本文以TMS320F28335微控制器为核心,提供了一种在实验过程中可根据当前反应电流改变量程的电化学仪设计方案。对于仪器重要组成部分如恒电位仪、I/V转换电路及波形发生电路介绍了其设计方法,详细阐述了下位机与上位机软件的工作流程。仪器结构简单、成本低廉,利用原理样机进行了循环伏安法实验并通过上位机软件绘制出伏安图,实验结果表明:设计方案可行,电化学仪能够正常工作。%In order to solve the problem caused by Fixed-range in electrochemistry experiments,a Range-changing electrochemistry Measuring Based on TMS320F28335 microcontroller is designed.We introduced the important parts of the instrument such as potentiostat,I/V conversion circuit,waveform generator.Elaborate the process of the software.The instrument has simple structure and low cost,A cyclic voltammetry experiment is carried out to test the prototype,the experimental show that the scheme is available.

  14. Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake.

    Science.gov (United States)

    Iyer, Abhishek; Van Lysebetten, Dorien; Ruiz García, Yara; Louage, Benoit; De Geest, Bruno G; Madder, Annemieke

    2015-04-01

    The basic DNA recognition region of the GCN4 protein comprising 23 amino acids has been modified to contain two optimally positioned cysteines which have been linked and stapled using cross-linkers of suitable lengths. This results in stapled peptides with a stabilized α-helical conformation which allows for DNA binding and concurrent enhancement of cellular uptake.

  15. Primary and repeated stapled hemorrhoidopexy for prolapsing hemorrhoids: Follow-up to five years

    DEFF Research Database (Denmark)

    Raahave, D.; Pedersen, I.K.; Jepsen, Lars Vedel

    2008-01-01

    Purpose: Treating hemorrhoids by stapled hemorrhoidopexy has become increasingly common, because the procedure results in less pain and allows the patient to return to work earlier than with open hemorrhoidectomy. However, the durability of stapled hemorrhoidopexy has not been evaluated. This stu...

  16. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.

    Directory of Open Access Journals (Sweden)

    Sharon Min Qi Chee

    Full Text Available As key negative regulator of the p53 tumour suppressor, Mdm2 is an attractive therapeutic target. Small molecules such as Nutlin have been developed to antagonise Mdm2, resulting in p53-dependent death of tumour cells. We have recently described a mutation in Mdm2 (M62A, which precludes binding of Nutlin, but not p53. This Nutlin-resistant variant is not, however, refractory to binding and inhibition by stapled peptide antagonists targeting the same region of Mdm2. A detailed understanding of how stapled peptides are recalcitrant to Mdm2 mutations conferring Nutlin-resistance will aid in the further development of potent Mdm2 antagonists. Here, we report the 2.00 Å crystal structure of a stapled peptide antagonist bound to Nutlin resistant Mdm2. The stapled peptide relies on an extended network of interactions along the hydrophobic binding cleft of Mdm2 for high affinity binding. Additionally, as seen in other stapled peptide structures, the hydrocarbon staple itself contributes to binding through favourable interactions with Mdm2. The structure highlights the intrinsic plasticity present in both Mdm2 and the hydrocarbon staple moiety, and can be used to guide future iterations of both small molecules and stapled peptides for improved antagonists of Mdm2.

  17. 75 FR 47795 - Certain Polyester Staple Fiber from Korea: Rescission of Antidumping Duty Administrative Review

    Science.gov (United States)

    2010-08-09

    ... International Trade Administration Certain Polyester Staple Fiber from Korea: Rescission of Antidumping Duty... (June 30, 2010). Scope of the Order Polyester staple fiber (``PSF'') covered by the scope of the order... polyesters measuring 3.3 decitex (3 denier, inclusive) or more in diameter. This merchandise is cut...

  18. 76 FR 52935 - Certain Polyester Staple Fiber From Korea: Rescission of Antidumping Duty Administrative Review

    Science.gov (United States)

    2011-08-24

    ... International Trade Administration Certain Polyester Staple Fiber From Korea: Rescission of Antidumping Duty... to request an administrative review of the antidumping order on polyester staple fiber from Korea... Reviews and Request for Revocation in Part, 76 FR 37781 (June 28, 2011). Scope of the Order...

  19. 76 FR 11268 - Certain Polyester Staple Fiber From Korea and Taiwan

    Science.gov (United States)

    2011-03-01

    ... COMMISSION Certain Polyester Staple Fiber From Korea and Taiwan AGENCY: United States International Trade Commission. ACTION: Institution five-year reviews concerning the antidumping duty orders on certain polyester... whether revocation of the antidumping duty orders on certain polyester staple fiber from Korea and...

  20. 78 FR 14512 - Certain Polyester Staple Fiber From the People's Republic of China: Preliminary Results and...

    Science.gov (United States)

    2013-03-06

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China... order on certain polyester staple fiber from the People's Republic of China (``PRC''). The period of... Sichuan Chemical Fiber Corp. and Huvis Sichuan Polyester Fiber Ltd. (``Huvis Sichuan'') are part of...

  1. A Cautionary Analysis of STAPLE Using Direct Inference of Segmentation Truth

    DEFF Research Database (Denmark)

    Van Leemput, Koen; Sabuncu, Mert R.

    2014-01-01

    regions are included in the model, STAPLE devolves into thresholding the average of the input segmentations. We further show that when the number of raters is small, the STAPLE result may not be the optimal segmentation truth estimate, and its model parameter estimates might not reflect the individual...

  2. Perioperative topical nitrate and sphincter function in patients undergoing transanal stapled anastomosis: a randomized, placebo-controlled, double-blinded trial.

    LENUS (Irish Health Repository)

    Winter, D C

    2012-02-03

    PURPOSE: The use of transanal stapling devices may impair continence because of digital dilatation and\\/or instrumentation. This study assessed the effect of pharmacological dilatation of the sphincter prior to stapler insertion. METHODS: A randomized, placebo-controlled, double-blinded study of 60 patients undergoing transanal stapled anastomosis was undertaken. Consenting patients were randomly assigned to receive a single intraoperative dose of topical 0.2 percent nitroglycerin (glyceryl trinitrate) ointment or nitroglycerin-free placebo. All patients were assessed preoperatively and postoperatively by clinical methods (Wexner incontinence scores and examination), anorectal manometry by a station pull-through technique, and endoanal ultrasonography. RESULTS: Intraoperative mean (+\\/-SEM) resting pressures (mmHg) were significantly reduced by nitroglycerin compared with prenitroglycerin levels (9.9 +\\/- 0.9 vs. 50.5 +\\/- 2.7; P = 0.002) or controls (56.0 +\\/- 3.2; P = 0.001). Twenty-one of the 28 controls (75 percent) but only 4 of the 32 patients in the nitroglycerin group (12.5 percent) required digital dilatation to insert the stapling instrument ( P = 0.003). Squeeze pressures were unaltered by the intervention but mean resting pressures were higher in the nitroglycerin group postoperatively (52.9 +\\/- 3.2 - 31.6 +\\/- 1.3 = 21.3 mmHg; 95 percent confidence interval, 14-27). Incontinence scores were lower in the nitroglycerin group at the 3-month (1.1 +\\/- 0.2 vs. 4.6 +\\/- 0.3; P = 0.003) and 12-month (0.9 +\\/- 0.1 vs. 4.4 +\\/- 0.3; P = 0.002) clinic visits. CONCLUSION: Preoperative nitroglycerin dilatation protects sphincter function in patients undergoing transanal stapled anastomoses.

  3. Estimation of inferential uncertainty in assessing expert segmentation performance from STAPLE.

    Science.gov (United States)

    Commowick, Olivier; Warfield, Simon K

    2010-03-01

    The evaluation of the quality of segmentations of an image, and the assessment of intra- and inter-expert variability in segmentation performance, has long been recognized as a difficult task. For a segmentation validation task, it may be effective to compare the results of an automatic segmentation algorithm to multiple expert segmentations. Recently an expectation-maximization (EM) algorithm for simultaneous truth and performance level estimation (STAPLE) was developed to this end to compute both an estimate of the reference standard segmentation and performance parameters from a set of segmentations of an image. The performance is characterized by the rate of detection of each segmentation label by each expert in comparison to the estimated reference standard. This previous work provides estimates of performance parameters,but does not provide any information regarding the uncertainty of the estimated values. An estimate of this inferential uncertainty, if available, would allow the estimation of confidence intervals for the values of the parameters. This would facilitate the interpretation of the performance of segmentation generators and help determine if sufficient data size and number of segmentations have been obtained to precisely characterize the performance parameters. We present a new algorithm to estimate the inferential uncertainty of the performance parameters for binary and multi-category segmentations. It is derived for the special case of the STAPLE algorithm based on established theory for general purpose covariance matrix estimation for EM algorithms. The bounds on the performance parameters are estimated by the computation of the observed information matrix.We use this algorithm to study the bounds on performance parameters estimates from simulated images with specified performance parameters, and from interactive segmentations of neonatal brain MRIs. We demonstrate that confidence intervals for expert segmentation performance parameters can be

  4. A Prospective Randomized Study Comparing Skin Staples and Polypropylene Sutures for Securing the Mesh in Lichtenstein's Repair

    Directory of Open Access Journals (Sweden)

    Pankaj Shivhare

    2014-06-01

    Results: Mesh fixation with skin staples is as effective as conventional sutures with the added advantage of significant reduction in the operating time and complications. Conclusions: The staples can be applied much more quickly than sutures for fixing the mesh, thus saving the operating time. The infection rate is significantly decreased with staples. The staples are not associated with any significant complications or recurrence. [Arch Clin Exp Surg 2014; 3(3.000: 147-152

  5. 78 FR 2366 - Certain Polyester Staple Fiber From the People's Republic of China: Final Results of Antidumping...

    Science.gov (United States)

    2013-01-11

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Final... of the antidumping duty order on certain polyester staple fiber (``PSF'') from the People's Republic... Polyester Staple Fiber From the People's Republic of China: Preliminary Results of the Antidumping...

  6. 76 FR 28420 - Certain Polyester Staple Fiber From the People's Republic of China: Full Extension of Preliminary...

    Science.gov (United States)

    2011-05-17

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Full... polyester staple fiber from the People's Republic of China (``PRC''). This review covers the period June 1... duty order on certain polyester staple fiber from the PRC. See Initiation of Antidumping...

  7. 77 FR 54898 - Certain Polyester Staple Fiber From the People's Republic of China: Final Results of Expedited...

    Science.gov (United States)

    2012-09-06

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Final... certain polyester staple fiber from the People's Republic of China (``PRC'') pursuant to section 751(c) of... duty order on certain polyester staple fiber from the PRC would be likely to lead to continuation...

  8. 78 FR 38939 - Certain Polyester Staple Fiber From the People's Republic of China: Final Results of Antidumping...

    Science.gov (United States)

    2013-06-28

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Final... antidumping duty order on certain polyester staple fiber (``PSF'') from the People's Republic of China (``PRC... below. \\1\\ See Certain Polyester Staple Fiber From the People's Republic of China: Preliminary...

  9. 75 FR 34097 - Certain Polyester Staple Fiber From Taiwan: Extension of the Final Results of Antidumping Duty...

    Science.gov (United States)

    2010-06-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of the Final Results of... certain polyester staple fiber from Taiwan. See Certain Polyester Staple Fiber from Taiwan:...

  10. 76 FR 60802 - Certain Polyester Staple Fiber From the Republic of Korea and Taiwan: Continuation of Antidumping...

    Science.gov (United States)

    2011-09-30

    ... International Trade Administration Certain Polyester Staple Fiber From the Republic of Korea and Taiwan... certain polyester staple fiber from the Republic of Korea (Korea) and Taiwan would likely lead to a... orders on polyester staple fiber from Korea and Taiwan \\1\\ pursuant to section 751(c) of the Tariff...

  11. 75 FR 76954 - Certain Polyester Staple Fiber From the People's Republic of China: Extension of Time Limit for...

    Science.gov (United States)

    2010-12-10

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Extension... Register the Preliminary Results of the second administrative review of certain polyester staple fiber.... See Certain Polyester Staple Fiber From the People's Republic of China: Notice of Preliminary...

  12. 76 FR 37830 - Polyester Staple Fiber From Korea and Taiwan; Scheduling of Expedited Five-Year Reviews...

    Science.gov (United States)

    2011-06-28

    ... COMMISSION Polyester Staple Fiber From Korea and Taiwan; Scheduling of Expedited Five-Year Reviews Concerning the Antidumping Duty Orders on Polyester Staple Fiber From Korea and Taiwan AGENCY: United States...) to determine whether revocation of the antidumping duty orders on polyester staple fiber from...

  13. 77 FR 21733 - Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2012-04-11

    ... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for... antidumping duty order on certain polyester staple fiber from Taiwan for the period May 1, 2010, through April 30, 2011.\\1\\ In Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for...

  14. 75 FR 64252 - Certain Polyester Staple Fiber From the Republic of Korea: Final Results of the 2008-2009...

    Science.gov (United States)

    2010-10-19

    ... International Trade Administration Certain Polyester Staple Fiber From the Republic of Korea: Final Results of... certain polyester staple fiber from the Republic of Korea and invited interested parties to comment. The... 15, 2010, the Department of Commerce (``the Department'') published Certain Polyester Staple...

  15. 76 FR 2886 - Certain Polyester Staple Fiber From the People's Republic of China: Final Results and Partial...

    Science.gov (United States)

    2011-01-18

    ... International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Final... second administrative review of the antidumping duty order on certain polyester staple fiber (``PSF'') from the People's Republic of China (``PRC''). See Certain Polyester Staple Fiber From the...

  16. 77 FR 50530 - Polyester Staple Fiber From China; Scheduling of an Expedited Five-Year Review Concerning the...

    Science.gov (United States)

    2012-08-21

    ... COMMISSION Polyester Staple Fiber From China; Scheduling of an Expedited Five-Year Review Concerning the Antidumping Duty Order on Polyester Staple Fiber From China AGENCY: United States International Trade... determine ] whether revocation of the antidumping duty order on polyester staple fiber from China would...

  17. 77 FR 71579 - Polyester Staple Fiber From Taiwan: Notice of Court Decision Not in Harmony With Final Results of...

    Science.gov (United States)

    2012-12-03

    ... International Trade Administration Polyester Staple Fiber From Taiwan: Notice of Court Decision Not in Harmony... order on polyester staple fiber from Taiwan covering the period of review (``POR'') May 1, 2009, through... Certain Polyester Staple Fiber From Taiwan: Final Results of Antidumping Duty Administrative Review, 76...

  18. 基于虚拟仪器技术的模拟视频自动测试系统%Automatic Test System of Analog Video Based on Virtual Instrument Technology

    Institute of Scientific and Technical Information of China (English)

    朱鹍; 曹伟洲

    2011-01-01

    文章介绍了一套基于虚拟仪器技术的模拟视频自动测试系统.详细论述了该系统的设计思路、硬件配置、软件操作界面设计以及实现方法.系统实现了各种格式、制式模拟视频信号的自动测试,大大提高了工作效率,并具有良好的扩展性,已经在某装备的生产和制造中得到应用.%The article describes an automatic test system of analog video based on virtual instrument technology. The design concept, hardware configuration, software functionality and implementation of system are discussed in detail. And a variety of formats, analog video signal automated test standard are achieved. The system improves the work efficiency greatly and has good scalability. It has been applied in a production and manufacturing equipment.

  19. A Route to Scale Up DNA Origami Using DNA Tiles as Folding Staples

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Zhao; Yan, Hao; Liu, Yan

    2010-01-26

    A new strategy is presented to scale up DNA origami using multi-helical DNA tiles as folding staples. Atomic force microscopy images demonstrate the two-dimensional structures formed by using this strategy.

  20. Exploitation of the Ornithine Effect Enhances Characterization of Stapled and Cyclic Peptides

    Science.gov (United States)

    Crittenden, Christopher M.; Parker, W. Ryan; Jenner, Zachary B.; Bruns, Kerry A.; Akin, Lucas D.; McGee, William M.; Ciccimaro, Eugene; Brodbelt, Jennifer S.

    2016-05-01

    A method to facilitate the characterization of stapled or cyclic peptides is reported via an arginine-selective derivatization strategy coupled with MS/MS analysis. Arginine residues are converted to ornithine residues through a deguanidination reaction that installs a highly selectively cleavable site in peptides. Upon activation by CID or UVPD, the ornithine residue cyclizes to promote cleavage of the adjacent amide bond. This Arg-specific process offers a unique strategy for site-selective ring opening of stapled and cyclic peptides. Upon activation of each derivatized peptide, site-specific backbone cleavage at the ornithine residue results in two complementary products: the lactam ring-containing portion of the peptide and the amine-containing portion. The deguanidination process not only provides a specific marker site that initiates fragmentation of the peptide but also offers a means to unlock the staple and differentiate isobaric stapled peptides.

  1. Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.

    Science.gov (United States)

    Speltz, Thomas E; Fanning, Sean W; Mayne, Christopher G; Fowler, Colin; Tajkhorshid, Emad; Greene, Geoffrey L; Moore, Terry W

    2016-03-18

    "Stapled" peptides are typically designed to replace two non-interacting residues with a constraining, olefinic staple. To mimic interacting leucine and isoleucine residues, we have created new amino acids that incorporate a methyl group in the γ-position of the stapling amino acid S5. We have incorporated them into a sequence derived from steroid receptor coactivator 2, which interacts with estrogen receptor α. The best peptide (IC50 =89 nm) replaces isoleucine 689 with an S-γ-methyl stapled amino acid, and has significantly higher affinity than unsubstituted peptides (390 and 760 nm). Through X-ray crystallography and molecular dynamics studies, we show that the conformation taken up by the S-γ-methyl peptide minimizes the syn-pentane interactions between the α- and γ-methyl groups.

  2. Endoscopic microwave coagulation therapy of postoperative hemorrhage from a stapled anastomosis.

    Science.gov (United States)

    Umano, Yasukazu; Horiuchi, Tetsuya; Inoue, Masaya; Shono, Yoshiharu; Oku, Yoshimasa; Tanishima, Hiroyuki; Tsuji, Takeshi; Tabuse, Katsuyoshi

    2005-01-01

    We experienced three cases of postoperative hemorrhage from a stapled gastrointestinal anastomosis, and established endoscopic microwave coagulation therapy (EMCT) with a cylinder-type electrode. We were able to treat postoperative hemorrhage over the entire circumference of stapled anastomosis successfully. Two patients had undergone a lower third thoracic esophagogastrectomy through a left thoraco-abdominal approach for gastric cancer in the cardia, while the other case had undergone Billroth I gastrectomy. They each had fresh bleeding from the stapled anastomosis after the operation. Emergency endoscopic examination was immediately performed. Endoscopy revealed bleeding on the suture line. We performed hemostasis endoscopically with microwave coagulation therapy safely. They were discharged from the hospital without complications such as leakage and stenosis. Since EMCT with the cylinder-type electrode can coagulate shallowly and widely, it is very effective for hemorrhage from a stapled anastomosis.

  3. Evaluation of Nitinol staples for the Lapidus arthrodesis in a reproducible biomechanical model

    Directory of Open Access Journals (Sweden)

    Nicholas Alexander Russell

    2015-12-01

    Full Text Available While the Lapidus procedure is a widely accepted technique for treatment of hallux valgus, the optimal fixation method to maintain joint stability remains controversial. The purpose of this study was to evaluate the biomechanical properties of new Shape Memory Alloy staples arranged in different configurations in a repeatable 1st Tarsometatarsal arthrodesis model. Ten sawbones models of the whole foot (n=5 per group were reconstructed using a single dorsal staple or two staples in a delta configuration. Each construct was mechanically tested in dorsal four-point bending, medial four-point bending, dorsal three-point bending and plantar cantilever bending with the staples activated at 37°C. The peak load, stiffness and plantar gapping were determined for each test. Pressure sensors were used to measure the contact force and area of the joint footprint in each group. There was a significant (p < 0.05 increase in peak load in the two staple constructs compared to the single staple constructs for all testing modalities. Stiffness also increased significantly in all tests except dorsal four-point bending. Pressure sensor readings showed a significantly higher contact force at time zero and contact area following loading in the two staple constructs (p < 0.05. Both groups completely recovered any plantar gapping following unloading and restored their initial contact footprint. The biomechanical integrity and repeatability of the models was demonstrated with no construct failures due to hardware or model breakdown. Shape memory alloy staples provide fixation with the ability to dynamically apply and maintain compression across a simulated arthrodesis following a range of loading conditions.

  4. Variation in Staple Food Prices in Eastern and Southern Africa: A Synthesis

    OpenAIRE

    2010-01-01

    The global food crisis of 2007-08 has focused attention on food prices, pushing the topic to the top of the agenda of international organizations. For policymakers in sub-Saharan Africa, however, food prices have been an issue of economic importance and political sensitivity for decades. Of particular importance are the prices of staple foods, defined as grains and starchy root crops that are inexpensive sources of calories. In eastern and southern Africa, maize is the most important staple f...

  5. Anastomotic leak rate and outcome for laparoscopic intra-corporeal stapled anastomosis

    OpenAIRE

    2010-01-01

    Aims :A prospective clinical audit of all patients undergoing laparoscopic surgery with the intention of primary colonic left-sided intracorporeal stapled anastomosis to identify the rate of anastomotic leaks on an intention to treat basis with or without defunctioning stoma. Materials and Methods : All patients undergoing laparoscopic colorectal surgery resulting in left-sided stapled anastomosis were included with no selection criteria applied. All operations were conducted by the same sur...

  6. Local Staple Food Price Indices in the Age of Biofuels

    Science.gov (United States)

    Brown, Molly E.

    2012-01-01

    In many poor, food insecure regions, agriculture is a primary source of income and farmers are reliant both on their own production and on purchasing food in the market to feed their families. Large local food price increases over a short time period can be indicative of a deteriorating food security situation and may be the consequence of weather-related food production declines, Dr can simply be the result of price transmission from the international commodity market. Food price indices developed by the United Nations Food and Agriculture Organization (FAO) are used to monitor food price trends at a global level, but largely reflect supply and demand conditions in export markets far from the places where the chronically food insecure live. A much better understanding of how local staple food prices in isolated regions such as West Africa that grow most of the food they eat to better understand the impact of global commodity market transformations on sensitive communities at the margin. This information will also enable improved strategies for these farmers who are extraordinarily sensitive to climate change impacts on agricultural growing conditions.

  7. Quality of Life after Stapled Hemorrhoidopexy: A Prospective Observational Study

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar Garg

    2013-01-01

    Full Text Available Objective. The objective of the study was to assess the change in quality of life (QOL of patients undergoing stapled hemorrhoidopexy (SH using WHO Quality of Life-BREF (WHOQOL-BREF questionnaire. Methods. The study sample comprised patients with symptomatic II, III, and IV degree hemorrhoids, undergoing SH. The patients were asked to complete WHOQOL-BREF questionnaire before and one month following the surgery. Result. There were 20 patients in the study group. The postoperative pain score measured by visual analogue scale at six hours postoperatively was at 24 hours. The items in the WHOQOL-BREF had high-internal consistency or reliability as shown by high Cronbach's alpha coefficient which was 0.82 and 0.90 for pre- and postoperative questionnaires. There was significant improvement in the overall perception of QOL and health, and in physical and psychological domains. There was modest improvement in environmental domain, while no change was noted in social domain. Conclusion. SH improved the quality of life of patients treated for hemorrhoids.

  8. Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic.

    Science.gov (United States)

    Bird, Gregory H; Madani, Navid; Perry, Alisa F; Princiotto, Amy M; Supko, Jeffrey G; He, Xiaoying; Gavathiotis, Evripidis; Sodroski, Joseph G; Walensky, Loren D

    2010-08-10

    The pharmacologic utility of lengthy peptides can be hindered by loss of bioactive structure and rapid proteolysis, which limits bioavailability. For example, enfuvirtide (Fuzeon, T20, DP178), a 36-amino acid peptide that inhibits human immunodeficiency virus type 1 (HIV-1) infection by effectively targeting the viral fusion apparatus, has been relegated to a salvage treatment option mostly due to poor in vivo stability and lack of oral bioavailability. To overcome the proteolytic shortcomings of long peptides as therapeutics, we examined the biophysical, biological, and pharmacologic impact of inserting all-hydrocarbon staples into an HIV-1 fusion inhibitor. We find that peptide double-stapling confers striking protease resistance that translates into markedly improved pharmacokinetic properties, including oral absorption. We determined that the hydrocarbon staples create a proteolytic shield by combining reinforcement of overall alpha-helical structure, which slows the kinetics of proteolysis, with complete blockade of peptide cleavage at constrained sites in the immediate vicinity of the staple. Importantly, double-stapling also optimizes the antiviral activity of HIV-1 fusion peptides and the antiproteolytic feature extends to other therapeutic peptide templates, such as the diabetes drug exenatide (Byetta). Thus, hydrocarbon double-stapling may unlock the therapeutic potential of natural bioactive polypeptides by transforming them into structurally fortified agents with enhanced bioavailability.

  9. Combined with work reality about styrene device dehydrogenation unit automatic control instrument system%结合工作实际谈谈苯乙烯装置脱氢单元自控仪表系统

    Institute of Scientific and Technical Information of China (English)

    於伟

    2013-01-01

    Is the original work unit and the host of the jiangsu chemical co.,LTD. 150000 tons of styrene plant DCS system are briefly introduced,and the styrene device dehydrogenation unit complex ratio control and V - 305 - T - 301 tower tank of uniform cascade control system in detail,and the F - 301 steam superheater outlet temperature TC - 3008,TC - 3015 - b respectively with fuel gas pressure PICA- 3003/3003,PICA - 3004/3004 b do control scheme of cascade control system,through discussing styrene dehydrogenation unit main control scheme of the automatic control instrument system,discusses the complex control algorithm in the ethylbenzene dehydrogenation stage control system%  就原工作单位江苏利士德化工有限公司15万吨苯乙烯装置 DCS 系统进行简要介绍,对苯乙烯装置上脱氢单元较复杂的 T-301塔比值控制和 V-305罐组成串级均匀控制系统做详细说明,并针对蒸汽过热炉 F-301出口温度 TC-3008,TC-3015分别与燃料气压力 PICA-3003/3003B,PICA-3004/3004B 组成的串级控制系统做控制方案说明,通过论述苯乙烯脱氢单元自控仪表系统的主要控制方案,探讨了复杂控制算法在乙苯脱氢阶段控制系统中的应用。

  10. Household Coverage of Fortified Staple Food Commodities in Rajasthan, India

    Science.gov (United States)

    Aaron, Grant J.; Sodani, Prahlad R.; Sankar, Rajan; Fairhurst, John; Siling, Katja; Guevarra, Ernest; Norris, Alison; Myatt, Mark

    2016-01-01

    A spatially representative statewide survey was conducted in Rajasthan, India to assess household coverage of atta wheat flour, edible oil, and salt. An even distribution of primary sampling units were selected based on their proximity to centroids on a hexagonal grid laid over the survey area. A sample of n = 18 households from each of m = 252 primary sampling units PSUs was taken. Demographic data on all members of these households were collected, and a broader dataset was collected about a single caregiver and a child in the first 2 years of life. Data were collected on demographic and socioeconomic status; education; housing conditions; recent infant and child mortality; water, sanitation, and hygiene practices; food security; child health; infant and young child feeding practices; maternal dietary diversity; coverage of fortified staples; and maternal and child anthropometry. Data were collected from 4,627 households and the same number of caregiver/child pairs. Atta wheat flour was widely consumed across the state (83%); however, only about 7% of the atta wheat flour was classified as fortifiable, and only about 6% was actually fortified (mostly inadequately). For oil, almost 90% of edible oil consumed by households in the survey was classified as fortifiable, but only about 24% was fortified. For salt, coverage was high, with almost 85% of households using fortified salt and 66% of households using adequately fortified salt. Iodized salt coverage was also high; however, rural and poor population groups were less likely to be reached by the intervention. Voluntary fortification of atta wheat flour and edible oil lacked sufficient industry consolidation to cover significant portions of the population. It is crucial that appropriate delivery channels are utilized to effectively deliver essential micronutrients to at-risk population groups. Government distribution systems are likely the best means to accomplish this goal. PMID:27760123

  11. Automatic Reading

    Institute of Scientific and Technical Information of China (English)

    胡迪

    2007-01-01

    <正>Reading is the key to school success and,like any skill,it takes practice.A child learns to walk by practising until he no longer has to think about how to put one foot in front of the other.The great athlete practises until he can play quickly,accurately and without thinking.Ed- ucators call it automaticity.

  12. Effect of hydrocarbon stapling on the properties of α-helical antimicrobial peptides isolated from the venom of hymenoptera.

    Science.gov (United States)

    Chapuis, Hubert; Slaninová, Jiřina; Bednárová, Lucie; Monincová, Lenka; Buděšínský, Miloš; Čeřovský, Václav

    2012-11-01

    The impact of inserting hydrocarbon staples into short α-helical antimicrobial peptides lasioglossin III and melectin (antimicrobial peptides of wild bee venom) on their biological and biophysical properties has been examined. The stapling was achieved by ring-closing olefin metathesis, either between two S-2-(4'-pentenyl) alanine residues (S (5)) incorporated at i and i + 4 positions or between R-2-(7'-octenyl) alanine (R (8)) and S (5) incorporated at the i and i + 7 positions, respectively. We prepared several lasioglossin III and melectin analogs with a single staple inserted into different positions within the peptide chains as well as analogs with double staples. The stapled peptides exhibited a remarkable increase in hemolytic activity, while their antimicrobial activities decreased. Some single stapled peptides showed a higher resistance against proteolytic degradation than native ones, while the double stapled analogs were substantially more resistant. The CD spectra of the singly stapled peptides measured in water showed only a slightly better propensity to form α-helical structure when compared to native peptides, whereas the doubly stapled analogs exhibited dramatically enhanced α-helicity.

  13. Stapled Peptides by Late-Stage C(sp(3) )-H Activation.

    Science.gov (United States)

    Noisier, Anaïs F M; García, Jesús; Ionuţ, Ioana A; Albericio, Fernando

    2017-01-02

    Despite the importance of stapled peptides for drug discovery, only few practical processes to prepare cross-linked peptides have been described; thus the structural diversity of available staple motifs is currently limited. At the same time, C-H activation has emerged as an efficient approach to functionalize complex molecules. Although there are many reports on the C-H functionalization of amino acids, examples of post-synthetic peptide C-H modification are rare and comprise almost only C(sp(2) )-H activation. Herein, we report the development of a palladium-catalyzed late-stage C(sp(3) )-H activation method for peptide stapling, affording an unprecedented hydrocarbon cross-link. This method was first employed to prepare a library of stapled peptides in solution. The compatibility with various amino acids as well as the influence of the size (i,i+3 and i,i+4) and length of the staple were investigated. Finally, a simple solid-phase procedure was also established.

  14. Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains.

    Science.gov (United States)

    Rezaei Araghi, Raheleh; Ryan, Jeremy A; Letai, Anthony; Keating, Amy E

    2016-05-20

    Alpha helices form a critical part of the binding interface for many protein-protein interactions, and chemically stabilized synthetic helical peptides can be effective inhibitors of such helix-mediated complexes. In particular, hydrocarbon stapling of peptides to generate constrained helices can improve binding affinity and other peptide properties, but determining the best stapled peptide variant often requires laborious trial and error. Here, we describe the rapid discovery and optimization of a stapled-helix peptide that binds to Mcl-1, an antiapoptotic protein that is overexpressed in many chemoresistant cancers. To accelerate discovery, we developed a peptide library synthesis and screening scheme capable of identifying subtle affinity differences among Mcl-1-binding stapled peptides. We used our method to sample combinations of non-natural amino-acid substitutions that we introduced into Mcl-1 inhibitors in the context of a fixed helix-stabilizing hydrocarbon staple that increased peptide helical content and reduced proteolysis. Peptides discovered in our screen contained surprising substitutions at sites that are conserved in natural binding partners. Library-identified peptide M3d is the most potent molecule yet tested for selectively triggering mitochondrial permeabilization in Mcl-1 dependent cell lines. Our library approach for optimizing helical peptide inhibitors can be readily applied to the study of other biomedically important targets.

  15. Measurement, instrumentation, and sensors handbook

    CERN Document Server

    Eren, Halit

    2014-01-01

    The Second Edition of the bestselling Measurement, Instrumentation, and Sensors Handbook brings together all aspects of the design and implementation of measurement, instrumentation, and sensors. Reflecting the current state of the art, it describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences and discusses processing systems, automatic data acquisition, reduction and analysis, operation characteristics, accuracy, errors, calibrations, and the incorporation of standards for control purposes. Organized acco

  16. Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.

    Science.gov (United States)

    Bird, Gregory H; Irimia, Adriana; Ofek, Gilad; Kwong, Peter D; Wilson, Ian A; Walensky, Loren D

    2014-12-01

    Hydrocarbon stapling can restore bioactive α-helical structure to natural peptides, yielding research tools and prototype therapeutics to dissect and target protein interactions. Here we explore the capacity of peptide stapling to generate high-fidelity, protease-resistant mimics of antigenic structures for vaccine development. HIV-1 has been refractory to vaccine technologies thus far, although select human antibodies can broadly neutralize HIV-1 by targeting sequences of the gp41 juxtamembrane fusion apparatus. To develop candidate HIV-1 immunogens, we generated and characterized stabilized α-helices of the membrane-proximal external region (SAH-MPER) of gp41. SAH-MPER peptides were remarkably protease resistant and bound to the broadly neutralizing 4E10 and 10E8 antibodies with high affinity, recapitulating the structure of the MPER epitope when differentially engaged by the two anti-HIV Fabs. Thus, stapled peptides may provide a new opportunity to develop chemically stabilized antigens for vaccination.

  17. Critical evaluation of strategies for mineral fortification of staple food crops.

    Science.gov (United States)

    Gómez-Galera, Sonia; Rojas, Eduard; Sudhakar, Duraialagaraja; Zhu, Changfu; Pelacho, Ana M; Capell, Teresa; Christou, Paul

    2010-04-01

    Staple food crops, in particular cereal grains, are poor sources of key mineral nutrients. As a result, the world's poorest people, generally those subsisting on a monotonous cereal diet, are also those most vulnerable to mineral deficiency diseases. Various strategies have been proposed to deal with micronutrient deficiencies including the provision of mineral supplements, the fortification of processed food, the biofortification of crop plants at source with mineral-rich fertilizers and the implementation of breeding programs and genetic engineering approaches to generate mineral-rich varieties of staple crops. This review provides a critical comparison of the strategies that have been developed to address deficiencies in five key mineral nutrients-iodine, iron, zinc, calcium and selenium-and discusses the most recent advances in genetic engineering to increase mineral levels and bioavailability in our most important staple food crops.

  18. Determination Testing of Seed Hardness of Staple Breeding Wheat Seed in Gansu Province of China

    OpenAIRE

    Fei Dai; Zhengsheng Han; Fengwei Zhang; Wuyun Zhao; Aimin Gao; Xingkai Li

    2015-01-01

    Seed hardness is one of the important indexes of grain classification. It has close relationship with grain powder, flour quality, seed storage and processing, resist insect pest and so on. In this study, which applied based on the grain hardness indentation loading curve method and chose 3 kind of staple breeding wheat seed to determine the seed hardness in Gansu province. The experimental results showed that the average hardness value of staple breeding wheat seed was 22.42 MPa~57.85 MPa an...

  19. Rectovaginal Fistula after Low Anterior Resection for Rectal Cancer Using a Double Stapling Technique

    Directory of Open Access Journals (Sweden)

    Satoshi Yodonawa

    2010-07-01

    Full Text Available A 55-year-old female underwent low anterior resection for rectal cancer using a double stapling technique. She developed a rectovaginal fistula on the 9th postoperative day. She was discharged from hospital after undergoing transverse colostomy, and 5 months later she underwent transvaginal repair of the rectovaginal fistula. She subsequently had an uneventful recovery. The leading cause of this complication is involvement of the posterior wall of the vagina in the staple line when firing the circular stapler. Transvaginal repair with a diverting stoma for rectovaginal fistula is a safe, minimally invasive and effective method.

  20. Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis.

    Science.gov (United States)

    Kim, Young-Woo; Grossmann, Tom N; Verdine, Gregory L

    2011-06-01

    This protocol provides a detailed procedure for the preparation of stapled α-helical peptides, which have proven their potential as useful molecular probes and as next-generation therapeutics. Two crucial features of this protocol are (i) the construction of peptide substrates containing hindered α-methyl, α-alkenyl amino acids and (ii) the ring-closing olefin metathesis (RCM) of the resulting resin-bound peptide substrates. The stapling systems described in this protocol, namely bridging one or two turns of an α-helix, are highly adaptable to most peptide sequences, resulting in favorable RCM kinetics, helix stabilization and promotion of cellular uptake.

  1. 76 FR 69702 - Certain Polyester Staple Fiber From the People's Republic of China: Final Results of Antidumping...

    Science.gov (United States)

    2011-11-09

    ....20.0025 and known to the industry as polyester staple fiber for spinning and generally used in woven... carpeting; and (3) low-melt polyester staple fiber defined as a bi- component fiber with an outer, non... and non-PRC exporters not listed above that have separate rates, the cash deposit rate will...

  2. 75 FR 5763 - Notice of Correction to the First Administrative Review of Certain Polyester Staple Fiber From...

    Science.gov (United States)

    2010-02-04

    ... International Trade Administration Notice of Correction to the First Administrative Review of Certain Polyester... antidumping duty order on certain polyester staple fiber from the People's Republic of China (``PRC''). See First Administrative Review of Certain Polyester Staple Fiber From the People's Republic of China:...

  3. 77 FR 4543 - Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2012-01-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for... antidumping duty order on certain polyester staple fiber from Taiwan for the period May 1, 2010, through...

  4. 75 FR 70906 - Certain Polyester Staple Fiber From the People's Republic of China: Partial Rescission of the...

    Science.gov (United States)

    2010-11-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Certain Polyester Staple Fiber From the People's Republic of China: Partial... certain polyester staple fiber (``PSF'') from the People's Republic of China (``PRC'') for the period...

  5. 76 FR 5331 - Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2011-01-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for... antidumping duty order on certain polyester staple fiber from Taiwan for the period May 1, 2009, through...

  6. Bioavailability of iron, zinc, and provitamin A carotenoids in biofortified staple crops

    Science.gov (United States)

    International research efforts, including those funded by HarvestPlus, are using conventional plant breeding to biofortify staple crops such as maize, rice, cassava, beans, wheat, sweet potatoes, and pearl millet, increasing the concentrations of micronutrients that are commonly deficient in specifi...

  7. Heavy and Toxic Metals in Staple Foodstuffs and Agriproduct from Contaminated Soils

    CERN Document Server

    Gorbunov, A V; Kistanov, A A; Lyapunov, S M; Okina, O I; Ramadan, A B

    2002-01-01

    This article presents basic data on the content of Cr, Fe, Ni, Cu, Zn, As, Cd, Sb, Hg, and Pb in staple foodstuffs and agriproduct grown in Russia (Astrakhan region and the town of Belovo) and Egypt (Helwan region). The dependence of the concentration of metals in agriproducts on the content and chemical form of existence in irrigation water and soils is indicated.

  8. Clive Staples Lewis’s Beliefs in Biblical Themes as reflected in the Chronicles of Narnia

    Institute of Scientific and Technical Information of China (English)

    李霞

    2009-01-01

    Clive Staples Lewis,British literary critic,scholar and author,often best known for his classic fantasy stories for children The Chronicles of Narnia.As a well-known Christian apologist,C.S.Lewis defended Christianity fervently in his works.This paper explores how his beliefs in biblical themes are reflected in his works.

  9. Randomized clinical trial of symptom control after stapled anopexy or diathermy excision for haemorrhoid prolapse

    DEFF Research Database (Denmark)

    Nyström, P-O; Qvist, N; Raahave, D;

    2010-01-01

    BACKGROUND: : This multicentre randomized clinical trial studied how symptoms improved after either stapled anopexy or diathermy excision of haemorrhoids. METHODS: : The study involved 18 hospitals in Sweden, Denmark and the UK. Some 207 patients were randomized to either anopexy or Milligan-Morg...

  10. Mucosectomy and stapled pouch-anal anastomosis in familial adenomatous polyposis

    DEFF Research Database (Denmark)

    Bülow, S

    2012-01-01

    In familial adenomatous polyposis, a restorative proctocolectomy with an ileo-anal pouch may be performed either with a mucosectomy and a hand-sewn anastomosis or as a stapled anastomosis without a mucosectomy. The disadvantage of the former is suboptimal bowel function and the disadvantage...

  11. Radioisotope instruments

    CERN Document Server

    Cameron, J F; Silverleaf, D J

    1971-01-01

    International Series of Monographs in Nuclear Energy, Volume 107: Radioisotope Instruments, Part 1 focuses on the design and applications of instruments based on the radiation released by radioactive substances. The book first offers information on the physical basis of radioisotope instruments; technical and economic advantages of radioisotope instruments; and radiation hazard. The manuscript then discusses commercial radioisotope instruments, including radiation sources and detectors, computing and control units, and measuring heads. The text describes the applications of radioisotop

  12. Introduction of all-hydrocarbon i,i+3 staples into alpha-helices via ring-closing olefin metathesis.

    Science.gov (United States)

    Kim, Young-Woo; Kutchukian, Peter S; Verdine, Gregory L

    2010-07-02

    The introduction of all-hydrocarbon i,i+3 staples into alpha-helical peptide scaffolds via ring-closing olefin metathesis (RCM) between two alpha-methyl,alpha-pentenylglycine residues incorporated at i and i+3 positions, which lie on the same face of the helix, has been investigated. The reactions were found to be highly dependent upon the side-chain stereochemistry of the amino acids undergoing RCM. The i,i+3 stapling system established here provides a potentially useful alternative to the well-established i,i+4 stapling system now in widespread use.

  13. Notes on instrumentation and control

    CERN Document Server

    Roy, G J

    2013-01-01

    Notes on Instrumentation and Control presents topics on pressure (i.e., U-tube manometers and elastic type gauges), temperature (i.e. glass thermometer, bi-metallic strip thermometer, filled system thermometer, vapor pressure thermometer), level, and flow measuring devices. The book describes other miscellaneous instruments, signal transmitting devices, supply and control systems, and monitoring systems. The theory of automatic control and semi-conductor devices are also considered. Marine engineers will find the book useful.

  14. Micro mushroom instrumentation system

    Science.gov (United States)

    Davidson, W. F.

    1986-01-01

    An electronics circuit which provides for the recording of instrumentation data on an optical disk is disclosed. The optical disk is formatted in a spiral format instead of concentric tracks. The spiral format allows data to be recorded without the gaps that would be associated with concentric tracks. The instrumentation system provides each channel with a program instrumentation amplifier, a six pole lowpass switched capacitor filter, a sample and hold amplifier, and a digital to analog converter to provide automatic offset capability. Since each channel has its own components, simultaneous samples of every channel can be captured. All of the input signal's channel variables can be captured. All of the input signal's channel variables can be changed under software control without hardware changes. A single board computer is used for a system controller.

  15. Lung abscess mimicking lung cancer developed around staples in a patient with permanent tracheostoma.

    Science.gov (United States)

    Watanabe, Yui; Aoki, Masaya; Suzuki, Soichi; Umehara, Tadashi; Harada, Aya; Wakida, Kazuhiro; Nagata, Toshiyuki; Kariatsumari, Kota; Nakamura, Yoshihiro; Sato, Masami

    2015-11-01

    A 68-year-old male with a tracheostoma due to hypopharyngeal cancer was admitted because his chest computed tomography (CT) showed a small nodule in the right middle lobe. Following a partial resection of the right middle lobe, histopathological diagnosis of the resected sample was that of organizing pneumonia. Eleven months later, chest CT showed a mass with pleural indentation and spiculation in the right middle lobe. 18-Fluorodeoxyglucose-positron emission tomography showed significant accumulation in the middle lobe tumor mass shadow. The abnormal chest shadow that had developed around surgical staples suggested inadequate resection and tumor recurrence. As the abnormal radiological shadow was enlarging, middle lobectomy was carried out. Histological examination revealed that the tumor was a lung abscess without malignant features. This is a unique case of lung abscess mimicking lung cancer which developed around staples used during partial resection of the lung.

  16. EVALUATION OF STAPLING TECHNIQUE IN SURGICAL TREATMENT OF ESOPHAGEALAND CARDIAC CANCER

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    To investigate an effective method to prevent anastomotic leakage and stenosis, evaluating the role of stapling technique in surgical treatment of esophageal and cardiac cancer. Methods: The stapling technique was used in end-to-side esophagogastromosis in surgical treatment of esophageal and cardiac cancer. Results: 128 patients were so treated. One patient died of superior mesenteric artery embolism, and the operative mortality was 0.78%. No anastomotic leakage or stenosis was found in this series. The other complications included postoperative thoracic cavity bleeding in 1 (0.78%), myocardial infarction in 2 (1.56%), stress ulcer of stomach in 1 (0.78%), and gastroparsis in 4 (3.12%). The overall morbidity rate was 4.7%. Conclusion: Using stapler to perform end-to-side esophagogastromosis has the advantages of being simple and safe, cutting short the operation time, and preventing leakage and stenosis. It is an ideal technique in the treatment of esophageal and cardiac cancer.

  17. Graphene/polyester staple composite for the removal of oils and organic solvents

    Science.gov (United States)

    Wu, Ruihan; Yu, Baowei; Liu, Xiaoyang; Li, Hongliang; Bai, Yitong; Ming, Zhu; Chen, Lingyun; Yang, Sheng-Tao; Chang, Xue-Ling

    2016-06-01

    Spongy graphene has been widely applied in oil removal. However, spongy graphene is hardly applicable for crude oil removal, because the complexity and high viscosity of crude oil. Herein, we reported that graphene/polyester staple composite (GPSC) could be used for the removal of oils and organic solvents, in particular crude oil. Graphene oxide was in situ reduced in the presence of polyester staple by hydrazine hydrate to form GPSC. GPSC efficiently adsorbed oils and organic solvents with high adsorption capacities. Demonstrations of treating pure oils and those in simulated sea water by GPSC were successfully performed. Due to the loose structure, GPSC adsorbed crude oil quickly with an adsorption capacity of 52 g g-1. During the regeneration, the adsorption capacity of GPSC retained around 78% of the initial capacity up to 9 cycles. The implication to the applications of GPSC in water remediation is discussed.

  18. Laparoscopic sleeve gastrectomy using a synthetic bioabsorbable staple line reinforcement material: Post-operative complications and 6 year outcomes

    Directory of Open Access Journals (Sweden)

    Mahdi Saleh

    2016-09-01

    Conclusion: The synthetic bioabsorbable reinforcement material shows no staple line leaks making it safe to use. LSG as a procedure had a high resolution of obesity-related comorbidities as well as sustainable long-term weight loss.

  19. Research on the properties of dope-dyed bamboo pulp staple fibers

    Science.gov (United States)

    Zhang, Y. J.

    2016-07-01

    In order to understand the properties of the dope-dyed bamboo pulp staple fibers, the moisture regains, tensile properties, friction properties and electrical conductivity of them and the white bamboo pulp fiber were tested, compared and analyzed. The results show that the moisture regains of the dope-dyed bamboo pulp fibers are smaller than the white bamboo pulp fiber's, whereas their friction coefficients, breaking strengths and elongations and mass ratio resistances are a bit larger.

  20. The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism.

    Directory of Open Access Journals (Sweden)

    Briana R Flaherty

    Full Text Available Drug resistance poses a significant threat to ongoing malaria control efforts. Coupled with lack of a malaria vaccine, there is an urgent need for the development of new antimalarials with novel mechanisms of action and low susceptibility to parasite drug resistance. Protein Kinase A (PKA has been implicated as a critical regulator of pathogenesis in malaria. Therefore, we sought to investigate the effects of disrupted PKA signaling as a possible strategy for inhibition of parasite replication. Host PKA activity is partly regulated by a class of proteins called A Kinase Anchoring Proteins (AKAPs, and interaction between HsPKA and AKAP can be inhibited by the stapled peptide Stapled AKAP Disruptor 2 (STAD-2. STAD-2 was tested for permeability to and activity against Plasmodium falciparum blood stage parasites in vitro. The compound was selectively permeable only to infected red blood cells (iRBC and demonstrated rapid antiplasmodial activity, possibly via iRBC lysis (IC50 ≈ 1 μM. STAD-2 localized within the parasite almost immediately post-treatment but showed no evidence of direct association with PKA, indicating that STAD-2 acts via a PKA-independent mechanism. Furosemide-insensitive parasite permeability pathways in the iRBC were largely responsible for uptake of STAD-2. Further, peptide import was highly specific to STAD-2 as evidenced by low permeability of control stapled peptides. Selective uptake and antiplasmodial activity of STAD-2 provides important groundwork for the development of stapled peptides as potential antimalarials. Such peptides may also offer an alternative strategy for studying protein-protein interactions critical to parasite development and pathogenesis.

  1. Sigmoid volvulus: is it a possible complication after stapled transanal rectal resection (STARR)?

    Science.gov (United States)

    Resta, G; Scagliarini, L; Bandi, M; Vedana, L; Marzetti, A; Ferrocci, G; Santini, M; Anania, G; Cavallesco, G; Baccarini, M

    2013-01-01

    We report a case of sigmoid volvulus post-stapled transanal rectal resection (STARR) for obstructed defecation. The patient, a 68-yearold woman with chronic constipation and dolichosigma, two days post-STARR presented severe abdominal pain. CT revealed sigmoid ischemia. The patient underwent resection of the sigmoid colon with end colostomy (Hartmann's procedure). Can STARR procedure produce a serious complication as sigmoid volvulus in patient with dolichosigma and obstructed defecation syndrome?

  2. Farmer groups enterprises and the marketing of staple food commodities in Africa:

    OpenAIRE

    Coulter, Jonathan

    2007-01-01

    "There are some apparently successful cases of collective marketing with staple food commodities (grains and root crops), but these are less common than cases involving higher value agricultural products. These can be attributed to the benefit/cost ratio to participants being generally higher for collective marketing of the higher-value crops. Some of the costs are ‘hidden', in the sense that they are borne by individuals in time spent in attending meetings, and not shown in the financial sta...

  3. Staple Food Consumption Patterns in Urban Kenya: Trends and Policy Implications

    OpenAIRE

    Muyanga, Milu; Jayne, Thom S.; Argwings-Kodhek, Gem; Ariga, Joshua

    2005-01-01

    This study examines current consumption patterns of the main staple carbohydrate products in Nairobi -- maize, wheat, rice, and cooking bananas -- in an effort to update policy makers’ knowledge of current urban food consumption patterns. The study also identifies the factors driving changes in the amount and form of urban maize meal consumption, in order to better understand how food security policy should be designed to respond to the needs of low-income consumers. The study reveals how con...

  4. Critical evaluation of strategies for mineral fortification of staple food crops

    OpenAIRE

    Gómez-Galera, Sonia; Rojas, Eduard; Sudhakar, Duraialagaraja; Zhu, Changfu; Ana M. Pelacho; Capell, Teresa; Christou, Paul

    2010-01-01

    Staple food crops, in particular cereal grains, are poor sources of key mineral nutrients. As a result, the world’s poorest people, generally those subsisting on a monotonous cereal diet, are also those most vulnerable to mineral deficiency diseases. Various strategies have been proposed to deal with micronutrient deficiencies including the provision of mineral supplements, the fortification of processed food, the biofortification of crop plants at source with miner...

  5. Anastomotic leak rate and outcome for laparoscopic intra-corporeal stapled anastomosis

    Directory of Open Access Journals (Sweden)

    Goriainov Vitali

    2010-01-01

    Full Text Available Aims :A prospective clinical audit of all patients undergoing laparoscopic surgery with the intention of primary colonic left-sided intracorporeal stapled anastomosis to identify the rate of anastomotic leaks on an intention to treat basis with or without defunctioning stoma. Materials and Methods : All patients undergoing laparoscopic colorectal surgery resulting in left-sided stapled anastomosis were included with no selection criteria applied. All operations were conducted by the same surgical team and the same preparation and intraoperative methods were used. The factors analyzed for this audit were patient demographics (age and sex, indication for operation, procedure performed, height of anastomosis, leak rate and the outcome, inpatient stay, mortality, rate of defunctioning stomas, and rate of conversion to open procedure. Results for anastomotic leakage were compared with known results from the Wessex Colorectal Audit for open colorectal surgery. Results : A total of 69 patients (43 females, 26 males; median age 69 years, range 19 - 86 years underwent colonic procedures with left-sided intracorporeal stapled anastomoses. Of these, 14 patients underwent reversal of Hartmann′s, 42 - Anterior Resection, 11 - Sigmoid Colectomy, 2 - Left Hemicolectomy. Excluding reversals of Hartmann′s, 29 operations were performed for malignant and 26 for benign disease. Five patients were defunctioned, and 3 were subsequently reversed. The median height of anastomosis was 12 cm, range 4 - 18 cm from anal verge as measured either intra-operatively, or by rigid sigmoidoscopy post-operatively. Four cases were converted to open surgery. There was 1 post-operative death within 30 days. There was 1 anastomotic leak (the patient that died, and 1 patient developed a colo-vesical fistula. Median post-operative stay was 7 days, range 2-19. Conclusion : This clinical audit confirms that the anastomotic leak rate for left-sided colorectal stapled anastomosis is no

  6. Maternal Consumption of Non-Staple Food in the First Trimester and Risk of Neural Tube Defects in Offspring

    OpenAIRE

    Meng Wang; Zhi-Ping Wang; Li-Jie Gao; Hui Yang; Zhong-Tang Zhao

    2015-01-01

    To study the associations between maternal consumption of non-staple food in the first trimester and risk of neural tube defects (NTDs) in offspring. Data collected from a hospital-based case-control study conducted between 2006 and 2008 in Shandong/Shanxi provinces including 459 mothers with NTDs-affected births and 459 mothers without NTDs-affected births. Logistic regression models were used to examine the associations between maternal consumption of non-staple food in the first trimester...

  7. Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces

    Science.gov (United States)

    Lama, Dilraj; Quah, Soo T.; Verma, Chandra S.; Lakshminarayanan, Rajamani; Beuerman, Roger W.; Lane, David P.; Brown, Christopher J.

    2013-12-01

    eIF4E is frequently over-expressed in different cancers and causes increased translation of oncogenic proteins via deregulated cap-dependent translation. Inhibitors of the eIF4E:eIF4G interactions represent an approach that would normalize cap-dependent translation. Stapled peptides represent an emerging class of therapeutics that can target protein: protein interactions. We present here molecular dynamics simulations for a set of rationally designed stapled peptides in solution and in complex with eIF4E, supported with biophysical and crystallographic data. Clustering of the simulated structures revealed the favoured conformational states of the stapled peptides in their bound or free forms in solution. Identifying these populations has allowed us to design peptides with improved affinities by introducing mutations into the peptide sequence to alter their conformational distributions. These studies emphasise the effects that engineered mutations have on the conformations of free and bound peptides, and illustrate that both states must be considered in efforts to attain high affinity binding.

  8. Ex Vivo Anatomical Characterization of Handsewn or Stapled Jejunocecal Anastomosis in Horses by Computed Tomography Scan.

    Science.gov (United States)

    Giusto, Gessica; Iotti, Bryan; Sammartano, Federica; Valazza, Alberto; Gandini, Marco

    2014-01-01

    The aim of this study is to compare handsewn and stapled jejunocecal anastomosis with different stomal lengths in terms of anatomical differences. Group 1 underwent a two-layer handsewn jejunocecal side-to-side anastomosis (HS); Group 2 received a stapled jejunocecal side-to-side anastomosis (GIA). Each group was divided into two subgroups (HS80 and HS100, GIA80 and GIA100). Specimens were inflated and CT scanned. The stomal/jejunal area ratio and blind end pouch volume/area were measured and compared. Effective length of the stoma was measured and compared with the initial length. Stomal/jejunal area ratio was 1.1 for both 80 techniques, 1.6 for the GIA100, and 1.9 for the HS100 technique. Both HS and GIA techniques produced a blind end pouch and exhibited a mean increase of the final stomal length ranging from 6 to 11% greater than the original stomal length. All techniques will exhibit a length increase of the final stomal length compared to the intended stomal length, with a consequent increase in stomal area. Stapled techniques consistently produced a large distal blind end pouch. Length of a jejunocecal anastomosis should be selected in accordance with the diameter of afferent jejunum, and the 80 mm stomal length could be deemed sufficient in horses.

  9. Ex Vivo Anatomical Characterization of Handsewn or Stapled Jejunocecal Anastomosis in Horses by Computed Tomography Scan

    Directory of Open Access Journals (Sweden)

    Gessica Giusto

    2014-01-01

    Full Text Available The aim of this study is to compare handsewn and stapled jejunocecal anastomosis with different stomal lengths in terms of anatomical differences. Group 1 underwent a two-layer handsewn jejunocecal side-to-side anastomosis (HS; Group 2 received a stapled jejunocecal side-to-side anastomosis (GIA. Each group was divided into two subgroups (HS80 and HS100, GIA80 and GIA100. Specimens were inflated and CT scanned. The stomal/jejunal area ratio and blind end pouch volume/area were measured and compared. Effective length of the stoma was measured and compared with the initial length. Stomal/jejunal area ratio was 1.1 for both 80 techniques, 1.6 for the GIA100, and 1.9 for the HS100 technique. Both HS and GIA techniques produced a blind end pouch and exhibited a mean increase of the final stomal length ranging from 6 to 11% greater than the original stomal length. All techniques will exhibit a length increase of the final stomal length compared to the intended stomal length, with a consequent increase in stomal area. Stapled techniques consistently produced a large distal blind end pouch. Length of a jejunocecal anastomosis should be selected in accordance with the diameter of afferent jejunum, and the 80 mm stomal length could be deemed sufficient in horses.

  10. Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling.

    Science.gov (United States)

    Hojo, Keiko; Hossain, Mohammed Akhter; Tailhades, Julien; Shabanpoor, Fazel; Wong, Lilian L L; Ong-Pålsson, Emma E K; Kastman, Hanna E; Ma, Sherie; Gundlach, Andrew L; Rosengren, K Johan; Wade, John D; Bathgate, Ross A D

    2016-08-25

    Structure-activity studies of the insulin superfamily member, relaxin-3, have shown that its G protein-coupled receptor (RXFP3) binding site is contained within its central B-chain α-helix and this helical structure is essential for receptor activation. We sought to develop a single B-chain mimetic that retained agonist activity. This was achieved by use of solid phase peptide synthesis together with on-resin ruthenium-catalyzed ring closure metathesis of a pair of judiciously placed i,i+4 α-methyl, α-alkenyl amino acids. The resulting hydrocarbon stapled peptide was shown by solution NMR spectroscopy to mimic the native helical conformation of relaxin-3 and to possess potent RXFP3 receptor binding and activation. Alternative stapling procedures were unsuccessful, highlighting the critical need to carefully consider both the peptide sequence and stapling methodology for optimal outcomes. Our result is the first successful minimization of an insulin-like peptide to a single-chain α-helical peptide agonist which will facilitate study of the function of relaxin-3.

  11. Helix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter.

    Science.gov (United States)

    Sviridov, D O; Ikpot, I Z; Stonik, J; Drake, S K; Amar, M; Osei-Hwedieh, D O; Piszczek, G; Turner, S; Remaley, A T

    2011-07-08

    Apolipoprotein mimetic peptides are short amphipathic peptides that efflux cholesterol from cells by the ABCA1 transporter and are being investigated as therapeutic agents for cardiovascular disease. We examined the role of helix stabilization of these peptides in cholesterol efflux. A 23-amino acid long peptide (Ac-VLEDSFKVSFLSALEEYTKKLNTQ-NH2) based on the last helix of apoA-I (A10) was synthesized, as well as two variants, S1A10 and S2A10, in which the third and fourth and third and fifth turn of each peptide, respectively, were covalently joined by hydrocarbon staples. By CD spectroscopy, the stapled variants at 24 °C were more helical in aqueous buffer than A10 (A10 17%, S1A10 62%, S2A10 97%). S1A10 and S2A10 unlike A10 were resistant to proteolysis by pepsin and chymotrypsin. S1A10 and S2A10 showed more than a 10-fold increase in cholesterol efflux by the ABCA1 transporter compared to A10. In summary, hydrocarbon stapling of amphipathic peptides increases their helicity, makes them resistant to proteolysis and enhances their ability to promote cholesterol efflux by the ABCA1 transporter, indicating that this peptide modification may be useful in the development of apolipoprotein mimetic peptides.

  12. Staple crops biofortified with increased vitamins and minerals: considerations for a public health strategy.

    Science.gov (United States)

    Garcia-Casal, Maria Nieves; Peña-Rosas, Juan Pablo; Giyose, Boitshepo

    2017-02-01

    Biofortification of staple crops has been proposed as a strategy to address micronutrient malnutrition, particularly with respect to insufficient intake of vitamin A, iron, zinc, and folate. The World Health Organization, in collaboration with the Food and Agriculture Organization of the United Nations and the Sackler Institute for Nutrition Science at the New York Academy of Sciences, convened a technical consultation entitled "Staple Crops Biofortified with Vitamins and Minerals: Considerations for a Public Health Strategy" in April 2016. Participants of the consultation reviewed the definition of biofortification of staple crops, patterns of crops production, processing, consumption, seed varieties, and micronutrient stability and bioavailability, as well as farmers' adoption and acceptability of the modified crops. Also discussed were economic, environmental, safety, and equity aspects of biofortified crops, as well as legal, policy, regulatory, and ethical issues for the implementation of biofortification strategies in agriculture and nutrition. Consultation working groups identified important and emerging technical issues, lessons learned, and research priorities to better support the evidence of improved nutrition and unintended adverse effects of biofortification. This paper provides the background and rationale of the technical consultation, synopsizes the presentations, and provides a summary of the main considerations proposed by the working groups.

  13. Estimated Dietary Exposure to Mycotoxins after Taking into Account the Cooking of Staple Foods in Japan

    Directory of Open Access Journals (Sweden)

    Shiro Saito

    2013-05-01

    Full Text Available Mycotoxins are commonly present in cereal grains and are not completely destroyed during their cooking and processing. When mycotoxins contaminate staple foods, the risk for exposure becomes serious. In East Asia, including Japan, rice is consumed as a staple food, and with the increasingly Westernized lifestyle, the consumption of wheat has increased. The mycotoxins commonly associated with rice and wheat are total aflatoxin (AFL and ochratoxin A (OTA, respectively. This study examined the retention of AFL and OTA during the cooking of rice and pasta. AFL was retained at 83%–89% the initial level after the cooking of steamed rice. In pasta noodles, more than 60% of the OTA was retained. These results show that AFL and OTA are relatively stable during the cooking process, suggesting that a major reduction in the exposure to these mycotoxins cannot be expected to occur by cooking rice and pasta. The estimated exposure assessment at the high consumer level (95th percentile and the mycotoxin contamination level determined by taking into account these reductions in the present study should be useful for the establishment of practical regulations for mycotoxins in staple foods.

  14. Basic Structure Design and Working Principle Analysis of the Photo electric Instrument to Automatically Sort Male and Female Silk worm Eggs%雌雄蚕卵光电自动分选仪器的基本结构设计与工作原理分析

    Institute of Scientific and Technical Information of China (English)

    宋礽苏; 蓝景平; 华娇; 夏世峰; 祝新荣; 陈诗; 孟智启

    2011-01-01

    依据雄蚕品种和限性卵色蚕品种不同性别的卵色差别,实现雌雄蚕卵全部存活的前提下自动、快速、准确分离.应用光电识别等原理设计的雌雄蚕卵分选仪器通过单通道光电计数控量供卵、多通道分流和转盘斜刮排序等技术,使蚕卵整齐有适当间距地排列成辐射状的48路,形成同时运行的48个单元,经可编程颜色传感器检测识别后,通过电磁分离器分选,将雌雄蚕卵分离.该雌雄蚕卵自动分选仪器的基本结构设计与工作原理可实现预期目标:不损伤雌蚕卵,使雌雄蚕卵都能存活;分选效率高,设计分卵速度达12万粒/h,准确率超过95%.%According to color difference of eggs from either male-specific silkworm varieties or egg-color sex-limited silkworm varieties, an instrument has been developed to fulfill the automatic, rapid and accurate separation of male and remale silkworm eggs while keeping both male and female eggs alive. This male and female silkworm eggs automatic separation instrument, designed based on electric and optical identification (EOID) and other mechanic principles, employed technologies such as controlling the amount of available eggs by single-channel optical counting, multi-channel diversion, and sorting by turntable and inclined scratching to make all silkworm eggs neatly arranged in 48 radial arrays with proper space between them, forming 48 units running at the same time. After detection and recognition by the programmable color sensor, male and female silkworm eggs were separated by an electromagnetic separator. The basic structure design and working principle of this male and female silkworm eggs automatic separation instrument could realize the expected objectives: it does not harm the female eggs, thus both male and female eggs are alive; it has high separation efficiency, with a designed sorting speed of 120 000 eggs/h and an accuracy rate of over 95%.

  15. Surgical staples compared with subcuticular suture for skin closure after cesarean delivery: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Sahar Assadi

    2016-03-01

    Full Text Available Background: Cesarean delivery is the most common surgical procedure and this prevalence is on the rise. Given these trends, cesarean wound complications, such as disruption or infection, remain an important cause of post-cesarean morbidity. Methods: We conducted a single-center randomized controlled trial that included women with viable pregnancies (≥24 weeks undergoing cesarean delivery at Motahary University Hospital, Urmia, Iran from April to November 2014. All cesarean types were included: scheduled or unscheduled and primary or repeat cesareans. Women were excluded for the following reasons: inability to obtain informed consent, immune compromising disease (e.g. AIDS, chronic steroid use, diabetic mellitus and BMI≥30. Of 266 women, 133 were randomized to staples and 133 women to suture group. Results: The mean±SD age of the staples group was 27.6±5.4 years and mean±SD age of suture was 28.7±5.9 years. Multiparity is the most frequent in both groups that by using Chi-square test, no significant differences were observed between the two groups (P=0.393. The most frequent indication for cesarean section in both groups was history of cesarean section in staple 40 cases (30.1% and suture 32 cases (24.1%. The survey was conducted using the Chi-square test was not significant (P=0.381. Pain at 6 weeks postoperatively was significantly less in the staple group (P=0.001. Operative time was longer with suture closure (4.68±0.67 versus 1.03±0.07 minute, P<0.001. The Vancouver scale score was significantly less in suture closure (6.6±0.8 versus 7.5±0.9, P=0.001. Wound disruption was significantly less in suture closure (3.8% versus 11.3%, P=0.017. Conclusion: The staple group had low pain and operation time but had a significant wound disruption and scar. The patients who have suffered a significant wound disruption were affected by age (P=0.022 and BMI (P=0.001 at compared those who were not affected by factors such as age or high BMI as

  16. Sutures versus staples for wound closure in orthopaedic surgery: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Shantz Jesse A

    2012-06-01

    Full Text Available Abstract Background A recently published meta-analysis comparing metallic staples to sutures in orthopaedic procedures revealed three fold increase in risk for infection in stapled wounds. The studies included in the meta-analysis are at risk of bias due to experimental design limitations. A large randomized controlled trial is proposed to direct orthopaedic surgeons in their choice of wound closure material. Methods/Design A parallel group randomized controlled trial with institutional review board approval will be conducted. Patients will be randomized intraoperatively to have skin wounds closed with sutures or staples. Dressings will be used to maintain blinding outcome assessors. The primary outcome measure will be a composite all-cause wound complication outcome measure composed of: infection, wound drainage, wound necrosis, blistering, dehiscence, suture abscess and material sensitivity reaction. An independent review board blinded to treatment assignment will adjudicate suspected complications based on clinical data. All deceased patients will also be reviewed. An interim analysis of complications will take place after half of the patients have been recruited. All data will be analyzed by a blinded statistician. Dichotomous primary and secondary outcome measures will be analyzed using the Chi-squared statistic. Continuous outcome measures will be analyzed using Student's t-test. Subgroup analysis will compare infection rates using sutures versus staples in each anatomic area (upper extremity, pelvis/acetabulum, hip/femur, knee, ankle. A further subgroup analysis will be conducted comparing trauma patients to elective surgery patients. Non-infected revision surgery will also be compared to primary surgery. Discussion Wound closure material is an afterthought for many orthopaedic surgeons. The combined results of several comparative trials suggests that the choice of wound closure materials may have an impact on the rate of surgical site

  17. An automatic hinge system for leg orthoses

    NARCIS (Netherlands)

    Rietman, J.S.; Goudsmit, J.; Meulemans, D.; Halbertsma, J.P.K.; Geertzen, J.H.B.

    2004-01-01

    This paper describes a new, automatic hinge system for leg orthoses, which provides knee stability in stance, and allows knee-flexion during swing. Indications for the hinge system are a paresis or paralysis of the quadriceps muscles. Instrumented gait analysis was performed in three patients, fitte

  18. Automatic Weather Station (AWS) Lidar

    Science.gov (United States)

    Rall, Jonathan A.R.; Abshire, James B.; Spinhirne, James D.; Smith, David E. (Technical Monitor)

    2000-01-01

    An autonomous, low-power atmospheric lidar instrument is being developed at NASA Goddard Space Flight Center. This compact, portable lidar will operate continuously in a temperature controlled enclosure, charge its own batteries through a combination of a small rugged wind generator and solar panels, and transmit its data from remote locations to ground stations via satellite. A network of these instruments will be established by co-locating them at remote Automatic Weather Station (AWS) sites in Antarctica under the auspices of the National Science Foundation (NSF). The NSF Office of Polar Programs provides support to place the weather stations in remote areas of Antarctica in support of meteorological research and operations. The AWS meteorological data will directly benefit the analysis of the lidar data while a network of ground based atmospheric lidar will provide knowledge regarding the temporal evolution and spatial extent of Type la polar stratospheric clouds (PSC). These clouds play a crucial role in the annual austral springtime destruction of stratospheric ozone over Antarctica, i.e. the ozone hole. In addition, the lidar will monitor and record the general atmospheric conditions (transmission and backscatter) of the overlying atmosphere which will benefit the Geoscience Laser Altimeter System (GLAS). Prototype lidar instruments have been deployed to the Amundsen-Scott South Pole Station (1995-96, 2000) and to an Automated Geophysical Observatory site (AGO 1) in January 1999. We report on data acquired with these instruments, instrument performance, and anticipated performance of the AWS Lidar.

  19. TH-C-18A-02: Machine Learning and STAPLE Based Simultaneous Longitudinal Segmentation of Bone and Marrow Structures From Dual Energy CT

    Energy Technology Data Exchange (ETDEWEB)

    Fehr, D; Schmidtlein, C; Hwang, S; Deasy, J; Veeraraghavan, H [Memorial Sloan Kettering Cancer Center, New York, NY (United States)

    2014-06-15

    Purpose: To develop a fully-automatic longitudinal bone and marrow segmentation method in the pelvic region from dual energy computed tomography (DECT). Methods: We developed a two-step automatic bone and marrow segmentation method for simultaneous longitudinal evaluation of patients with metastatic bone disease using dual energy CT (DECT). Our approach transforms the DECT images into a multi-material decomposition (MMD) model that represents the voxels as a mixture of multiple materials. A support vector machine (SVM) was trained using a single scan. In the first step of the longitudinal segmentation the trained SVM model detects bone and marrow structures on all available longitudinal scans. Segmentation is further refined through active contour segmentation. In the second step, the segmentations from the individual scans are merged by employing the simultaneous truth and performance level estimation (STAPLE) algorithm. The scans are registered using affine and deformable registration. We found that our approach improves the segmentation in all the scans under reliable registration performance between the same scans. Improving registration was not under the scope of this work. Results: We applied our approach to segment bone and marrow in DECT scans in the pelvic regions for multiple patients. Each patient had three to five follow up scans. All the patients in the analysis had artificial metal prostheses which introduced challenges for the registration. Our algorithm achieved reasonable accurate segmentation despite the presence of metal artifacts and high-density oral contrast in neighboring structures. Our approach obtained an overall segmentation accuracy of 80% using DICE metric. Conclusion: We developed a two-step automatic longitudinal segmentation technique for bone and marrow region structures in the pelvic areas from dual energy CT. Our approach achieves robust segmentation despite the presence of confounding structures with similar intensities as the

  20. Design of Onboard Instrument Based on Virtual Instrument Technology

    Institute of Scientific and Technical Information of China (English)

    TANG Baoping; ZHONG Yuanchang; QIU Jianwei

    2006-01-01

    After analyzing and comparing the traditional automobile instrument, the onboard instrument based on virtual instrument technology is designed in this paper. The PC/104 computer was employed as the core processing unit of the onboard instrument, and the several intelligent data acquisition nodes are set and connected by the CAN bus, through which the nodes can communicate with the core processing unit. The information of the vehicle's working condition can be displayed synthetically by adopting virtual instrument technology. When the working condition goes beyond its limit, the system can emit an alarm, record and storage the abnormal condition automatically, and suggest how to deal with the abnormity urgently. The development background and design idea of onboard information system were elaborated in the paper. The software, the hardware architecture and the principle of onboard information system were introduced in detail.

  1. 30万t/aPVC装置乙炔站自控仪表改造%Modifications on automatic control instruments of acetylene generating station for 30 000 t/a PVC production facility

    Institute of Scientific and Technical Information of China (English)

    张春严

    2012-01-01

    Modifications were made on the DCS power supply system, automatic control sys- tems for the nitrogen replacement of upper hopper and acetylene generator feeding, and the sodium hypochlorite preparation system in the acetylene generating station for 30 000 t/a PVC production facility. Thus, the production reliability of acetylene generating station was improved, the hidden hazards were eliminated, and the labour intensity was reduced.%对30万t/aPVC装置乙炔站的DCS供电系统、发生器上储斗充氮置换及加料自控系统、次氯酸钠配制系统进行了改造,通过改造提高了乙炔站生产的可靠性,消除了安全隐患,降低了劳动强度。

  2. Procedure of brewing alcohol as a staple food: case study of the fermented cereal liquor "Parshot" as a staple food in Dirashe special woreda, southern Ethiopia.

    Science.gov (United States)

    Sunano, Yui

    2016-07-01

    For most brews, alcohol fermentation and lactic fermentation take place simultaneously during the brewing process, and alcohol fermentation can progress smoothly because the propagation of various microorganisms is prevented by lactic fermentation. It is not necessary to cause lactic fermentation with a thing generated naturally and intentionally. The people living in the Dirashe area in southern Ethiopia drink three types of alcoholic beverages that are prepared from cereals. From these alcoholic beverages, parshot is prepared by the addition of plant leaves for lactic fermentation and nech chaka by adding cereal powder for lactic fermentation before alcohol fermentation. People living in the Dirashe area partake of parshot as part of their staple diet. The brewing process used for parshot and a food culture with alcoholic beverages as parts of the staple diet are rare worldwide. This article discusses the significance of using lactic fermentation before alcoholic fermentation and focuses on lactic fermentation in the brewing methods used for the three kinds of alcoholic beverages consumed in the Dirashe area. We initially observed the brewing process and obtained information about the process from the people in that area. Next, we determined the pH and analyzed the lactic acid (g/100 g) and ethanol (g/100 g) content during lactic fermentation of parshot and nech chaka; the ethyl acetate (mg/100 g) and volatile base nitrogen (mg/100 g) content during this period was also analyzed. In addition, we compared the ethanol (g/100 g) content of all three kinds of alcoholic beverages after completion of brewing. The results showed that it was possible to consume large quantities of these alcoholic beverages because of the use of lactic fermentation before alcoholic fermentation, which improved the safety and preservation characteristics of the beverages by preventing the propagation of various microorganisms, improving flavor, and controlling the alcohol level.

  3. Instrumentation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides instrumentation support for flight tests of prototype weapons systems using a vast array of airborne sensors, transducers, signal conditioning and encoding...

  4. Breakfast staple types affect brain gray matter volume and cognitive function in healthy children.

    Science.gov (United States)

    Taki, Yasuyuki; Hashizume, Hiroshi; Sassa, Yuko; Takeuchi, Hikaru; Asano, Michiko; Asano, Kohei; Kawashima, Ryuta

    2010-12-08

    Childhood diet is important for brain development. Furthermore, the quality of breakfast is thought to affect the cognitive functioning of well-nourished children. To analyze the relationship among breakfast staple type, gray matter volume, and intelligence quotient (IQ) in 290 healthy children, we used magnetic resonance images and applied voxel-based morphometry. We divided subjects into rice, bread, and both groups according to their breakfast staple. We showed that the rice group had a significantly larger gray matter ratio (gray matter volume percentage divided by intracranial volume) and significantly larger regional gray matter volumes of several regions, including the left superior temporal gyrus. The bread group had significantly larger regional gray and white matter volumes of several regions, including the right frontoparietal region. The perceptual organization index (POI; IQ subcomponent) of the rice group was significantly higher than that of the bread group. All analyses were adjusted for age, gender, intracranial volume, socioeconomic status, average weekly frequency of having breakfast, and number of side dishes eaten for breakfast. Although several factors may have affected the results, one possible mechanism underlying the difference between the bread and the rice groups may be the difference in the glycemic index (GI) of these two substances; foods with a low GI are associated with less blood-glucose fluctuation than are those with a high GI. Our study suggests that breakfast staple type affects brain gray and white matter volumes and cognitive function in healthy children; therefore, a diet of optimal nutrition is important for brain maturation during childhood and adolescence.

  5. Breakfast staple types affect brain gray matter volume and cognitive function in healthy children.

    Directory of Open Access Journals (Sweden)

    Yasuyuki Taki

    Full Text Available Childhood diet is important for brain development. Furthermore, the quality of breakfast is thought to affect the cognitive functioning of well-nourished children. To analyze the relationship among breakfast staple type, gray matter volume, and intelligence quotient (IQ in 290 healthy children, we used magnetic resonance images and applied voxel-based morphometry. We divided subjects into rice, bread, and both groups according to their breakfast staple. We showed that the rice group had a significantly larger gray matter ratio (gray matter volume percentage divided by intracranial volume and significantly larger regional gray matter volumes of several regions, including the left superior temporal gyrus. The bread group had significantly larger regional gray and white matter volumes of several regions, including the right frontoparietal region. The perceptual organization index (POI; IQ subcomponent of the rice group was significantly higher than that of the bread group. All analyses were adjusted for age, gender, intracranial volume, socioeconomic status, average weekly frequency of having breakfast, and number of side dishes eaten for breakfast. Although several factors may have affected the results, one possible mechanism underlying the difference between the bread and the rice groups may be the difference in the glycemic index (GI of these two substances; foods with a low GI are associated with less blood-glucose fluctuation than are those with a high GI. Our study suggests that breakfast staple type affects brain gray and white matter volumes and cognitive function in healthy children; therefore, a diet of optimal nutrition is important for brain maturation during childhood and adolescence.

  6. Delayed Failure after Endoscopic Staple Repair of an Anterior Spine Surgery Related Pharyngeal Diverticulum

    Directory of Open Access Journals (Sweden)

    Samer Al-Khudari

    2013-01-01

    Full Text Available We present a rare complication of endoscopic staple repair of a pharyngeal diverticulum related to prior anterior cervical spine surgery. A 70-year-old male developed a symptomatic pharyngeal diverticulum 2 years after an anterior cervical fusion that was repaired via endoscopic stapler-assisted diverticulectomy. He initially had improvement of his symptoms after the stapler-assisted approach. Three years later, the patient presented with dysphagia and was found to have erosion of the cervical hardware into the pharyngeal lumen at the site of the prior repair. We present the first reported case of late hardware erosion into a pharyngeal diverticulum after endoscopic stapler repair.

  7. Stapled transanal rectal resection for obstructed defecation syndrome associated with rectocele and rectal intussusception

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To evaluate the safety and efficacy of stapled transanal rectal resection(STARR),and to analyze the outcome of the patients 12-mo after the operation.METHODS:From May 2007 to October 2008,50 female patients with rectocele and/or rectal intussusception underwent STARR.The preoperative status,perioperative and postoperative complications at baseline,3,6 and 12-mo were assessed.Data were collected prospectively from standardized questionnaires for the assessment of constipation[constipation scoring system,...

  8. Automatic Fiscal Stabilizers

    Directory of Open Access Journals (Sweden)

    Narcis Eduard Mitu

    2013-11-01

    Full Text Available Policies or institutions (built into an economic system that automatically tend to dampen economic cycle fluctuations in income, employment, etc., without direct government intervention. For example, in boom times, progressive income tax automatically reduces money supply as incomes and spendings rise. Similarly, in recessionary times, payment of unemployment benefits injects more money in the system and stimulates demand. Also called automatic stabilizers or built-in stabilizers.

  9. Comparison of Oct-2-enyl and Oct-4-enyl Staples for Their Formation and α-Helix Stabilizing Effects

    Energy Technology Data Exchange (ETDEWEB)

    Pham, Thanh K.; Yoo, Jiyeon; Kim, Youngwoo [Dongguk Univ., Seoul (Korea, Republic of)

    2013-09-15

    The all-hydrocarbon i,i+4 stapling system using an oct-4-enyl crosslink is one of the most widely employed chemical tools to stabilize an α-helical conformation of a short peptide. This crosslinking system has greatly extended our ability to modulate intracellular protein-macromolecule interactions. The helix-inducing property of the i,i+4 staple has shown to be highly dependent on the length and the stereochemistry of the oct-4-enyl crosslink. Here we show that changing the double bond position within the i,i+4 staple has a considerable impact not only on the formation of the crosslink but also on α-helix induction. The data further increases the understanding of the structure-activity relationships of this valuable chemical tool.

  10. Automatic differentiation bibliography

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, G.F. (comp.)

    1992-07-01

    This is a bibliography of work related to automatic differentiation. Automatic differentiation is a technique for the fast, accurate propagation of derivative values using the chain rule. It is neither symbolic nor numeric. Automatic differentiation is a fundamental tool for scientific computation, with applications in optimization, nonlinear equations, nonlinear least squares approximation, stiff ordinary differential equation, partial differential equations, continuation methods, and sensitivity analysis. This report is an updated version of the bibliography which originally appeared in Automatic Differentiation of Algorithms: Theory, Implementation, and Application.

  11. Luminescence Instrumentation

    DEFF Research Database (Denmark)

    Jain, Mayank; Bøtter-Jensen, Lars

    2014-01-01

    This chapter gives an introduction to instrumentation for stimulated luminescence studies, with special focus on luminescence dating using the natural dosimeters, quartz and feldspars. The chapter covers basic concepts in luminescence detection, and thermal and optical stimulation, and reference...... irradiation. It then briefly describes development of spectrometers in dating applications, and finally gives an overview of recent development in the field directly linked to novel instrumentation. Contents of Paper...

  12. Comparison of a modified anoscope and the purse-string anoscope in stapled haemorrhoidopexy

    Institute of Scientific and Technical Information of China (English)

    Ali Dogan Bozdag; Ismail Yaman; Hayrullah Derici; Tugrul Tansug; Vedat Deniz

    2009-01-01

    AIM: To compare the results of the anoscope of the PPH kit and a modified anoscope during stapled haemorrhoidopexy.METHODS: The hospital records of 37 patients who underwent stapled haemorrhoidopexy between 2001 and 2006 were reviewed. The purse-string suture anoscope in the PPH kit was used on 15 patients (Group 1),and the modified anoscope was used on 22 patients(Group 2). Demographic characteristics of the patients,operation time, surgeon's performance, analgesic requirement, and complications were compared.RESULTS: Operation time was significantly longer in Group 1 (42.0±8.4 min vs 27.7±8.0 min, P = 0.039).The surgeons reported their operative performance as significantly better in Group 2 (the results of the assessments were poor in ten, medium in four and good in one in Group 1, while good in all patients in Group 2, P < 0.001). The need for haemostatic sutures was significantly higher in Group 1 (six cases) and was needed in two cases in Group 2 ( P = 0.034).CONCLUSION: Operation time decreased and the surgeon's satisfaction increased with use of the modified anoscope, and fewer haemostatic sutures were required if the surgeon waited longer before and after firing the stapler.

  13. Determination Testing of Seed Hardness of Staple Breeding Wheat Seed in Gansu Province of China

    Directory of Open Access Journals (Sweden)

    Fei Dai

    2015-02-01

    Full Text Available Seed hardness is one of the important indexes of grain classification. It has close relationship with grain powder, flour quality, seed storage and processing, resist insect pest and so on. In this study, which applied based on the grain hardness indentation loading curve method and chose 3 kind of staple breeding wheat seed to determine the seed hardness in Gansu province. The experimental results showed that the average hardness value of staple breeding wheat seed was 22.42 MPa~57.85 MPa and the dispersion of the hardness value was small, which also between 3~12%. The seed hardness of breeding wheat of Western drought-resistant No.1 was maximum (52.36~61.36MPa and the seed hardness of breeding wheat of Western drought-resistant No.3 between two parties of the other breeding wheat, which was 42.12~50.20MPa. The seed hardness of breeding wheat of Western drought-resistant No.2 was minimum, which were 58.10~62.91% and 47.91~54.66% lower than the rest of the two breeding wheat seed hardness respectively. The findings will provide theoretical basis for seed production and processing and the stimulation analysis by EDEM.

  14. Challenges in Targeting a Basic Helix-Loop-Helix Transcription Factor with Hydrocarbon-Stapled Peptides.

    Science.gov (United States)

    Edwards, Amanda L; Meijer, Dimphna H; Guerra, Rachel M; Molenaar, Remco J; Alberta, John A; Bernal, Federico; Bird, Gregory H; Stiles, Charles D; Walensky, Loren D

    2016-11-18

    Basic helix-loop-helix (bHLH) transcription factors play critical roles in organism development and disease by regulating cell proliferation and differentiation. Transcriptional activity, whether by bHLH homo- or heterodimerization, is dependent on protein-protein and protein-DNA interactions mediated by α-helices. Thus, α-helical decoys have been proposed as potential targeted therapies for pathologic bHLH transcription. Here, we developed a library of stabilized α-helices of OLIG2 (SAH-OLIG2) to test the capacity of hydrocarbon-stapled peptides to disrupt OLIG2 homodimerization, which drives the development and chemoresistance of glioblastoma multiforme, one of the deadliest forms of human brain cancer. Although stapling successfully reinforced the α-helical structure of bHLH constructs of varying length, sequence-specific dissociation of OLIG2 dimers from DNA was not achieved. Re-evaluation of the binding determinants for OLIG2 self-association and stability revealed an unanticipated role of the C-terminal domain. These data highlight potential pitfalls in peptide-based targeting of bHLH transcription factors given the liabilities of their positively charged amino acid sequences and multifactorial binding determinants.

  15. A Simple and Safe Procedure to Repair Rectal Prolapse Perineally Using Stapling Devices

    Directory of Open Access Journals (Sweden)

    Fumitake Hata

    2014-01-01

    Full Text Available Rectal prolapses are not life-threatening, however the bleeding and fecal incontinence associated with them significantly erode quality of life and can cause concern among patients' caregivers in nursing homes. Many procedures have been reported that repair rectal prolapses, and the procedure used depends on the severity of the prolapse; however, the treatments are yet to be established. Here we report a simple and safe procedure to repair rectal prolapse perineally using stapling devices. We performed this procedure on 5 patients within a short time. All patients were followed up for over 24 months and none had any recurrences of their rectal prolapses. No complications occurred during the operations and postoperative periods. Most patients who have prolapses are elderly and fragile, so the treatment must be easy, safe, and rapid. While rectal prolapse is not life-threatening, the goal of treatment is to alleviate its symptoms. The procedure we describe is consistent with this concept. We suggest that this procedure, which uses surgical stapling devices, might be a better option for the treatment of complete rectal prolapse. We will continue to surgically correct complete rectal prolapses and investigate the long-term outcomes of the procedure.

  16. Trade Liberalization, Exchange Rate Changes, and the Competitiveness of Carbohydrate Staple Markets in Nigeria

    Directory of Open Access Journals (Sweden)

    Maduabuchi Mkpado

    2012-06-01

    Full Text Available This study examined the effects of trade liberalization andexchange rate changes on carbohydrate staples in Nigeria.Secondary data published from 1974 to 2006 on cassava exportsand rice imports as well as non-tradable carbohydrate stapleswere used. It was hypothesized that exchange rate changes andtrade liberalization via price relatives, trade intensity and nominalprotection coefficient have affected prices of carbohydrate staplesin Nigeria. Results show that the effects of trade liberalizationon prices of non tradable carbohydrate staples were mixed.Trade liberalization accounted for most changes in the price ofnon tradable rice than other crops. World prices positivelyaffected the prices of maize and non tradable rice. Also increasingexchange rate will lead to increase in price of non tradable ricedue to price competition with imported rice. The intensificationof liberalization exercise from the removal of quantitativerestriction to use of tariff, among other recommendations, shouldbe encouraged because it can be a remedy to the negativeimpact of increase in the trade intensity and erosion of nominalprotection coefficient on prices of the non tradable crops.

  17. Evaluation of stapled closure following laryngectomy for carcinoma larynx in an Indian tertiary cancer centre

    Directory of Open Access Journals (Sweden)

    S Babu

    2015-01-01

    Full Text Available Background And Aim: Stapling devices are used for pharyngeal closure after laryngectomy for the past few decades although it has not gained wide acceptance. This study is aimed at evaluating the role of stapler in pharyngeal closure after laryngectomy. Methods: Thirty consecutive patients who underwent stapled laryngectomy at our institution from October 2004 to February 2008 were evaluated retrospectively. Linear stapler (Proximate TX 60; Ethicon Inc. was used for closure of neopharynx. Results: There were 28 males and 2 females with mean age of 54.5 years (54.5 ± 11.2. Nineteen of these patients (63.3% had salvage laryngectomy and two patients (6.7% had laryngectomy for a second primary tumor. Twenty-eight patients had total laryngectomy (TL, whereas two had extended TL. Eight patients had salivary leak (26.7%. Of these, 6 (75% had prior radiation. All salivary leaks except one were managed conservatively. Follow-up ranged from 7 to 54 months (median: 21 months. Seven patients (23.3% developed recurrence, six at the stoma, of which 5 (83.3% had initial extension of disease to the subglottis. Four-year disease-free survival was 54.4%. Conclusion: Pharyngeal closure by linear stapler is an efficient and safe method of fashioning the neopharynx after laryngectomy with no added risk of occurrence of pharyngocutaneous fistula in primary and salvage laryngectomies.

  18. Transgenic biofortification of the starchy staple cassava (Manihot esculenta) generates a novel sink for protein.

    Science.gov (United States)

    Abhary, Mohammad; Siritunga, Dimuth; Stevens, Gene; Taylor, Nigel J; Fauquet, Claude M

    2011-01-25

    Although calorie dense, the starchy, tuberous roots of cassava provide the lowest sources of dietary protein within the major staple food crops (Manihot esculenta Crantz). (Montagnac JA, Davis CR, Tanumihardjo SA. (2009) Compr Rev Food Sci Food Saf 8:181-194). Cassava was genetically modified to express zeolin, a nutritionally balanced storage protein under control of the patatin promoter. Transgenic plants accumulated zeolin within de novo protein bodies localized within the root storage tissues, resulting in total protein levels of 12.5% dry weight within this tissue, a fourfold increase compared to non-transgenic controls. No significant differences were seen for morphological or agronomic characteristics of transgenic and wild type plants in the greenhouse and field trials, but relative to controls, levels of cyanogenic compounds were reduced by up to 55% in both leaf and root tissues of transgenic plants. Data described here represent a proof of concept towards the potential transformation of cassava from a starchy staple, devoid of storage protein, to one capable of supplying inexpensive, plant-based proteins for food, feed and industrial applications.

  19. Modality of wound closure after total knee replacement: are staples as safe as sutures? A retrospective study of 181 patients

    Directory of Open Access Journals (Sweden)

    Hammerberg E Mark

    2011-10-01

    Full Text Available Abstract Background Surgical site wound closure plays a vital role in post-operative success. This effect is magnified in regard to commonly performed elective procedures such as total knee arthroplasty. The use of either sutures or staples for skin re-approximation remains a contested subject, which may have a significant impact on both patient safety and surgical outcome. The literature remains divided on this topic. Methods Two cohorts of patients at a level one trauma and regional referral center were reviewed. Cohorts consisted of consecutive total knee arthroplasties performed by two surgeons who achieved surgical wound re-approximation by either staples or absorbable subcuticular sutures. Outcome variables included time of surgery, wound dehiscence, surgical site infection per Center for Disease Control criteria and repeat procedures for debridement and re-closure. Results 181 patients qualified for study inclusion. Staples were employed in 82 cases (45.3% of total and sutures in 99 cases (54.7%. The staples group had no complications while the sutures group had 9 (9.1%. These consisted of: 4 infections (2 superficial, one deep, one organ/space; three patients required re-suturing for dehiscence; one allergic type reaction to suture material; and one gout flare resulting in dehiscence. The mean surgical time with sutures was 122.3 minutes (sd = 33.4 and with staples was 114 minutes (sd = 24.4. Conclusion This study demonstrated significantly fewer complications with staple use than with suture use. While all complications found in this study cannot be directly attributed to skin re-approximation method, the need for further prospective, randomized trials is established.

  20. Mediation and Automatization.

    Science.gov (United States)

    Hutchins, Edwin

    This paper discusses the relationship between the mediation of task performance by some structure that is not inherent in the task domain itself and the phenomenon of automatization, in which skilled performance becomes effortless or phenomenologically "automatic" after extensive practice. The use of a common simple explicit mediating…

  1. Digital automatic gain control

    Science.gov (United States)

    Uzdy, Z.

    1980-01-01

    Performance analysis, used to evaluated fitness of several circuits to digital automatic gain control (AGC), indicates that digital integrator employing coherent amplitude detector (CAD) is best device suited for application. Circuit reduces gain error to half that of conventional analog AGC while making it possible to automatically modify response of receiver to match incoming signal conditions.

  2. Automatic Differentiation Package

    Energy Technology Data Exchange (ETDEWEB)

    2007-03-01

    Sacado is an automatic differentiation package for C++ codes using operator overloading and C++ templating. Sacado provide forward, reverse, and Taylor polynomial automatic differentiation classes and utilities for incorporating these classes into C++ codes. Users can compute derivatives of computations arising in engineering and scientific applications, including nonlinear equation solving, time integration, sensitivity analysis, stability analysis, optimization and uncertainity quantification.

  3. Instrumented SSH

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Scott; Campbell, Scott

    2009-05-27

    NERSC recently undertook a project to access and analyze Secure Shell (SSH) related data. This includes authentication data such as user names and key fingerprints, interactive session data such as keystrokes and responses, and information about noninteractive sessions such as commands executed and files transferred. Historically, this data has been inaccessible with traditional network monitoring techniques, but with a modification to the SSH daemon, this data can be passed directly to intrusion detection systems for analysis. The instrumented version of SSH is now running on all NERSC production systems. This paper describes the project, details about how SSH was instrumented, and the initial results of putting this in production.

  4. Geotechnical instrumentation

    Science.gov (United States)

    Green, G. E.; Mikkelsen, P. E.; Mayne, P. W.; Frost, D. D.; Dowding, C. H.

    1988-12-01

    The 11 papers in the report deal with the following areas: deformation measurements with inclinometers; dilatometer experience in Washington, D.C., and vicinity; ground vibration monitoring instrumentation and computerized surveillance; instrumentation for tests of piles subjected to axial loading; use of the wave equation by the North Carolina Department of Transportation; NYSDOT's construction control of pile foundations with dynamic pile testing; discussion of procedures for the determination of pile capacity; modern specification of driven pile work; analysis of laterally loaded piles with nonlinear bending behavior; unified design of piles and pile groups, and LTBASE, a computer program for the analysis of laterally loaded piers including base and slope effects.

  5. Evaluating the synchronicity in yield variations of staple crops at global scale

    Science.gov (United States)

    Yokozawa, M.

    2014-12-01

    Reflecting the recent globalization trend in world commodity market, several major production countries are producing large amount of staple crops, especially, maize and soybean. Thus, simultaneous crop failure (abrupt reduction in crop yield, lean year) due to extreme weather and/or climate change could lead to unstable food supply. This study try to examine the synchronicity in yield variations of staple crops at global scale. We use a gridded crop yields database, which includes the historical year-to-year changes in staple crop yields with a spatial resolution of 1.125 degree in latitude/longitude during a period of 1982-2006 (Iizumi et al. 2013). It has been constructed based on the agriculture statistics issued by local administrative bureaus in each country. For the regions being lack of data, an interpolation was conducted to obtain the values referring to the NPP estimates from satellite data as well as FAO country yield. For each time series of the target crop yield, we firstly applied a local kernel regression to represent the long-term trend component. Next, the deviations of yearly yield from the long-term trend component were defined as ΔY(i, y) in year y at grid i. Then, the correlation of deviation between grids i and j in year y is defined as Cij(y) = ΔY(i, y) ΔY(j, y). In addition, Pij = represents the time-averaged correlation of deviation between grids i and j. Bracket means the time average operation over 25 years (1982-2006). As the results, figures show the time changes in the number of grid pairs, in which both the deviation are negative. It represent the time changes in ratio of the grid pairs where both crop yields synchronically decreased to the total grid pairs. The years denoted by arrows in the figures indicate the case that all the ratios of three country pairs (i.e. China-USA, USA-Brazil and Brazil-China) are relatively larger (>0.6 for soybean and >0.5 for maize). This suggests that the reductions in crop yield occurred

  6. PLC Based Automatic Multistoried Car Parking System

    OpenAIRE

    2014-01-01

    This project work presents the study and design of PLC based Automatic Multistoried Car Parking System. Multistoried car parking is an arrangement which is used to park a large number of vehicles in least possible place. For making this arrangement in a real plan very high technological instruments are required. In this project a prototype of such a model is made. This prototype model is made for accommodating twelve cars at a time. Availability of the space for parking is detecte...

  7. Thirty-seven patients treated with the C-seal : protection of stapled colorectal anastomoses with a biodegradable sheath

    NARCIS (Netherlands)

    Morks, Annelien N.; Havenga, Klaas; Hoedemaker, Henk O. ten Cate; Leijtens, Jeroen W. A.; Ploeg, Rutger J.

    2013-01-01

    The present study was performed to get a better insight in the incidence of anastomotic leakage leading to reintervention when using the C-seal: a biodegradable sheath that protects the stapled colorectal anastomosis from leakage. The C-seal is a thin walled tube-like sheath that forms a protective

  8. Canada's resource economy in transition : the past, present, and future of Canadian staples industries

    Energy Technology Data Exchange (ETDEWEB)

    Howlett, M. [Simon Fraser Univ., Burnaby, BC (Canada). Dept. of Political Science; Brownsey, K. [Mount Royal College, Calgary, AB (Canada). Dept. of Policy Studies] (eds.)

    2008-07-01

    This book examined changes in contemporary Canadian primary resource staples-driven political economies. It referred to the period of transition in which sectors moved from older models of staples development to post-staples modes of production. Specialists provided overviews of past and present developments of principal primary stables economies and discussed issues that are now changing modes of production. Subjects included genetically modified foods; aquaculture; forest certification; the participation of First Nations and other communities in mining project developments; and the growth of the offshore oil and gas industry. The book demonstrated that all sectors followed a similar pattern of rapid growth followed by resource depletion. Sectors now face additional challenges due to more complex regulatory and production environments. Challenges include determining appropriate levels of environmental protection, integrating high technology inputs, and successfully navigating free trade treaties and open competition. The book was divided into the following 5 main sections: (1) an introduction; (2) the post-staples state in theory and practice; (3) consumption industries : agriculture and the fisheries; (4) extraction industries : minerals and forests; and (5) transmission industries : oil and gas and water. refs., tabs., figs.

  9. 76 FR 38612 - Certain Polyester Staple Fiber From the Republic of Korea and Taiwan: Final Results of the...

    Science.gov (United States)

    2011-07-01

    ... International Trade Administration Certain Polyester Staple Fiber From the Republic of Korea and Taiwan: Final... Commerce (the Department) initiated the second sunset reviews of the antidumping duty orders on polyester... otherwise processed for spinning, of polyesters measuring 3.3 decitex (3 denier, inclusive) or more...

  10. Mycotoxins and cyanogenic glycosides in staple foods of three indigenous people of the Colombian Amazon.

    Science.gov (United States)

    Diaz, Gonzalo J; Krska, Rudolf; Sulyok, Michael

    2015-01-01

    A study was conducted to determine the incidence and levels of mycotoxins in the main staple foods of three indigenous people of the Colombian Amazon. A total of 20 corn, 24 rice and 59 cassava samples were analysed by a multi-analyte liquid chromatography-tandem mass spectrometry method covering the major classes of mycotoxins. In addition, cassava samples were also analysed for cyanogenic glycosides. The indigenous Amazon communities tested are exposed to potentially carcinogenic mycotoxins (particularly aflatoxins), as well as other mycotoxins, mainly through the intake of locally grown corn. Citrinin content in this corn was unusually high and has not been reported elsewhere. Two cassava samples contained high levels of cyanogenic glycosides. It is strongly recommended not to grow corn in the Amazon but instead purchase it from vendors capable of guaranteeing mycotoxin levels below the maximum allowable concentration in Colombia.

  11. A Systematic Review of Perennial Staple Crops Literature Using Topic Modeling and Bibliometric Analysis.

    Science.gov (United States)

    Kane, Daniel A; Rogé, Paul; Snapp, Sieglinde S

    2016-01-01

    Research on perennial staple crops has increased in the past ten years due to their potential to improve ecosystem services in agricultural systems. However, multiple past breeding efforts as well as research on traditional ratoon systems mean there is already a broad body of literature on perennial crops. In this review, we compare the development of research on perennial staple crops, including wheat, rice, rye, sorghum, and pigeon pea. We utilized the advanced search capabilities of Web of Science, Scopus, ScienceDirect, and Agricola to gather a library of 914 articles published from 1930 to the present. We analyzed the metadata in the entire library and in collections of literature on each crop to understand trends in research and publishing. In addition, we applied topic modeling to the article abstracts, a type of text analysis that identifies frequently co-occurring terms and latent topics. We found: 1.) Research on perennials is increasing overall, but individual crops have each seen periods of heightened interest and research activity; 2.) Specialist journals play an important role in supporting early research efforts. Research often begins within communities of specialists or breeders for the individual crop before transitioning to a more general scientific audience; 3.) Existing perennial agricultural systems and their domesticated crop material, such as ratoon rice systems, can provide a useful foundation for breeding efforts, accelerating the development of truly perennial crops and farming systems; 4.) Primary research is lacking for crops that are produced on a smaller scale globally, such as pigeon pea and sorghum, and on the ecosystem service benefits of perennial agricultural systems.

  12. Benign anastomotic stricture following transthoracic subtotal oesophagectomy and stapled oesophago-gastrostomy: risk factors and management

    Science.gov (United States)

    Dresner; Lamb; Wayman; Hayes; Griffin

    2000-03-01

    AIMS: Benign anastomotic stricture (BAS) is a common cause of dysphagia following oesophagectomy. The aim of this study was to assess the incidence of BAS, identify risk factors for its development and evaluate the results of postoperative endoscopic dilatation. METHODS: A consecutive series of 234 patients undergoing oesophagectomy with a stapled intrathoracic oesophagogastric anastomosis (Autosuture CEEA gun) between April 1990 and April 1999 were studied. BAS was defined as dysphagia with anastomotic narrowing (XQ200 endoscope) and no suspicion of recurrence. Statistical analysis was by the chi2 and Mann-Whitney U tests. RESULTS: The postoperative mortality rate was 5 per cent (12 of 234) and the anastomotic leak rate 3 per cent (six of 234). One-third of patients (70 of 222) who survived surgery re-presented with dysphagia; 5 per cent (11 of 222) were found to have proven local recurrence and 27 per cent (59 of 222) BAS. The median time to development of BAS was 92 (range 24-210) days. BAS formation was significantly related to the size of the staple gun employed: 21 mm, 80 per cent (eight of ten); 25 mm, 32 per cent (25 of 78); 28 mm, 23 per cent (19 of 81); 31 mm, 19 per cent (seven of 37) and 34 mm, 0 per cent (none of five) (chi2 = 18.3, 4 d.f., P risk factor for BAS formation and 'tilt-top' devices enable the use of a larger head with a subsequently lower incidence of BAS. Endoscopic dilatation is an effective treatment for BAS which rarely recurs and always resolves within 18 months.

  13. A Systematic Review of Perennial Staple Crops Literature Using Topic Modeling and Bibliometric Analysis

    Science.gov (United States)

    2016-01-01

    Research on perennial staple crops has increased in the past ten years due to their potential to improve ecosystem services in agricultural systems. However, multiple past breeding efforts as well as research on traditional ratoon systems mean there is already a broad body of literature on perennial crops. In this review, we compare the development of research on perennial staple crops, including wheat, rice, rye, sorghum, and pigeon pea. We utilized the advanced search capabilities of Web of Science, Scopus, ScienceDirect, and Agricola to gather a library of 914 articles published from 1930 to the present. We analyzed the metadata in the entire library and in collections of literature on each crop to understand trends in research and publishing. In addition, we applied topic modeling to the article abstracts, a type of text analysis that identifies frequently co-occurring terms and latent topics. We found: 1.) Research on perennials is increasing overall, but individual crops have each seen periods of heightened interest and research activity; 2.) Specialist journals play an important role in supporting early research efforts. Research often begins within communities of specialists or breeders for the individual crop before transitioning to a more general scientific audience; 3.) Existing perennial agricultural systems and their domesticated crop material, such as ratoon rice systems, can provide a useful foundation for breeding efforts, accelerating the development of truly perennial crops and farming systems; 4.) Primary research is lacking for crops that are produced on a smaller scale globally, such as pigeon pea and sorghum, and on the ecosystem service benefits of perennial agricultural systems. PMID:27213283

  14. Biomechanical and histological evaluation of a laparoscopic stapled gastropexy technique in dogs.

    Science.gov (United States)

    Hardie, R J; Flanders, J A; Schmidt, P; Credille, K M; Pedrick, T P; Short, C E

    1996-01-01

    The biochemical holding strength and histological characteristics of a laparoscopic stapled gastropexy (LG) adhesion were compared with that of an incisional gastropexy (IG) adhesion. An LG was performed in 14 dogs and an IG was performed in six dogs. During the LG procedure, the abdomen was insufflated with carbon dioxide and three cannulae were placed in the caudal aspect of the right side of the abdomen. A 35 mm laparoscopic stapler was used to staple the gastric antrum to the adjacent right lateral abdominal wall. The IG procedure was performed through ventral midline celiotomy. A 35 mm IG was made by apposing the gastric antrum to the adjacent right lateral abdominal wall with two continuous rows of suture. Half of each group of dogs was euthanatized at 7 and 30 days after surgery. The mean tensile load to failure at 7 days was 44.86 +/- 18.54 N for the LG group and 85.33 +/- 23.59 N for the IG group (P < .05). At 30 days the values were 72.39 +/- 18.01 N for the LG group and 71.17 +/-12.11 N for the IG group (P = .41). The gastropexy adhesions in the 7-day postoperative group contained variable amounts of fibrin, hemorrhage, mononuclear cell inflammation, loose fibrovascular tissue, and mature collagenous connective tissue. Adhesions in the 7-day postoperative group were divided subjectively into three histological subgroups based on the relative amounts of mature connective tissue within the adhesion. The LG and IG adhesions were randomly distributed among these subgroups (P = 1.0). Adhesions in the 30-day postoperative group contained well-organized fibrous connective tissue. No difference in the amount of connective tissue could be detected histologically in the LG or IG adhesions. Complications with the LG procedure included stomach perforation (2 cases), splenic puncture (2 cases), and subcutaneous emphysema (4 cases).

  15. On the relevance of spectral features for instrument classification

    DEFF Research Database (Denmark)

    Nielsen, Andreas Brinch; Sigurdsson, Sigurdur; Hansen, Lars Kai

    2007-01-01

    Automatic knowledge extraction from music signals is a key component for most music organization and music information retrieval systems. In this paper, we consider the problem of instrument modelling and instrument classification from the rough audio data. Existing systems for automatic instrument...... classification operate normally on a relatively large number of features, from which those related to the spectrum of the audio signal are particularly relevant. In this paper, we confront two different models about the spectral characterization of musical instruments. The first assumes a constant envelope...

  16. IDENTIFICATION AUTOMATIQUE DES INSTRUMENTS DE MUSIQUE

    OpenAIRE

    Livshin, Arie

    2007-01-01

    The thesis deals with various aspects of Automatic Musical Instrument Recognition (AMIR). AMIR means, intuitively speaking, that given a musical recording, the computer attempts to identify which parts of the music are performed by which musical instruments. AMIR research has gained popularity over the last 10 years especially due to its applicability as a component inside "Intelligent" music search-engines, which can allow searching the Internet or mass-storage devices in personal "MP3" play...

  17. A General Method for Module Automatic Testing in Avionics Systems

    Directory of Open Access Journals (Sweden)

    Li Ma

    2013-05-01

    Full Text Available The traditional Automatic Test Equipment (ATE systems are insufficient to cope with the challenges of testing more and more complex avionics systems. In this study, we propose a general method for module automatic testing in the avionics test platform based on PXI bus. We apply virtual instrument technology to realize the automatic testing and the fault reporting of signal performance. Taking the avionics bus ARINC429 as an example, we introduce the architecture of automatic test system as well as the implementation of algorithms in Lab VIEW. The comprehensive experiments show the proposed method can effectively accomplish the automatic testing and fault reporting of signal performance. It greatly improves the generality and reliability of ATE in avionics systems.

  18. Word Automaticity of Tree Automatic Scattered Linear Orderings Is Decidable

    CERN Document Server

    Huschenbett, Martin

    2012-01-01

    A tree automatic structure is a structure whose domain can be encoded by a regular tree language such that each relation is recognisable by a finite automaton processing tuples of trees synchronously. Words can be regarded as specific simple trees and a structure is word automatic if it is encodable using only these trees. The question naturally arises whether a given tree automatic structure is already word automatic. We prove that this problem is decidable for tree automatic scattered linear orderings. Moreover, we show that in case of a positive answer a word automatic presentation is computable from the tree automatic presentation.

  19. Active instruments

    DEFF Research Database (Denmark)

    Lim, Miguel Antonio; Ørberg, Jakob Williams

    2017-01-01

    themselves. We draw on two multi-year field studies of India and Denmark to investigate how national reforms and developments within the ranking industry interact in often surprising ways. Rankings do not always do what policy makers expect. We (1) highlight the activity of rankers in these two countries, (2......) show the dynamic nature of policy processes, and (3) consider the search for policy reference points among the different actors. We present rankers in motion, policies in motion, and finally the complex nature of the ranking device that needs to be both a relevant and malleable policy instrument...

  20. An automatic swinging instrument for better neonatal growing environment

    Science.gov (United States)

    Lu, Cheng-Hsing; Luo, Ching-Hsing; Chen, Yung-Jung; Yeh, Tsu-Fuh

    1997-08-01

    It is well known that a swing can help infants fall asleep easily. In conditions of deep sleep, infants can grow faster. But how and when to swing (including swing speed and amplitude) for better growth is a serious question. As of now, of concern is that there is no objective quantitative research concerning this topic, although there exist some qualitative studies in the literature. This project is directed to designing a swing system that can simulate a natural or forced swing vibration with a quiet close-loop magnetic driving technique. Both the frequency and amplitude of the system can be changed independently in the range of 0.4-1 Hz and 0.36°-3.6°, respectively. Therefore, the infant's quantitative physiological signals (e.g., electroencephalogram, energy consumption, sleep duration) can be measured to determine the best method of swinging. This system would help a lot of neonates, especially premature infants whose growth rate is much lower than it is in the mother's body.

  1. Analysis Performance Assessment of ESR-30 Automatic ESR Instrument and Biological Reference Intervals of Red Blood Cell Sedimentation Rate in Healthy Populations%ESR-30型全自动血沉分析仪性能评价及健康人群血红细胞沉降率生物参考区间的建立

    Institute of Scientific and Technical Information of China (English)

    刘爱胜; 陈荣贵; 文艳; 施俊柱

    2012-01-01

    目的 用ESR-30型全自动血沉分析仪检测健康人群红细胞沉降率,建立该方法的红细胞沉降率生物参考区间,为临床提供更准确的诊断参考依据,并与血红细胞沉降率的经典方法(魏氏法)进行对比试验,评价两者结果的相关性.方法 收集医院体检中心经体检医生全面检查未发现有引起血红细胞沉降率改变的各种非生理性疾病的人群共372例,其中男165例,女207例,50岁42例,用ESR-30型全自动血沉仪测定其血红细胞沉降率,对数据进行统计学分析与比较,并随机抽取临床标本54例,其中男24例,女30例,年龄17岁~62岁,用ESR-30型和经典方法(魏氏法)同时对比测定并统计分析两者测定结果的相关性.结果 ESR-30型全自动血沉仪检测健康人群血红细胞沉降率的生物参考区间为:男性小儿组(50岁)为2.0~45.9 mm/h,女性小儿组(50岁)为2.0~48.3 mm/h,除小儿组外其它不同性别、不同年龄组间ESR-30型全自动血沉仪测定的血红细胞沉降率差异有统计学意义(P50 years o1d:42 cases. Their blood erythrocyte sedimentation rates were determined with ESR-30 automatic ESR instrument and did the statistical analysis and comparison of the data. And randomly selected 54 cases of clinical specimens, 24 cases of male and 30 cases of female, the age of 17~62 years old. Analysed the correlation of two measurement results between the ESR-30 and classical methods (Wilcoxon method). Results ESR-30 automatic ESR was detected in healthy population of blood erythrocyte sedimentation rate of the biological reference interval for the group of young men (10 to 30 years old) :ma1e pediatric group (50 years old) to 2. 0~45. 9 mm/h,the female children ( 0. 05) ,the correlation of the two methods (r= 0. 814). Conclusion ESR-30 automatic ESR meter is a new method for detection of ESR,fast, accurate and reliable results with the Wilcoxon method,is worthy of clinical use. Different ages and gender of blood

  2. Automatic Program Development

    DEFF Research Database (Denmark)

    by members of the IFIP Working Group 2.1 of which Bob was an active member. All papers are related to some of the research interests of Bob and, in particular, to the transformational development of programs and their algorithmic derivation from formal specifications. Automatic Program Development offers......Automatic Program Development is a tribute to Robert Paige (1947-1999), our accomplished and respected colleague, and moreover our good friend, whose untimely passing was a loss to our academic and research community. We have collected the revised, updated versions of the papers published in his...... honor in the Higher-Order and Symbolic Computation Journal in the years 2003 and 2005. Among them there are two papers by Bob: (i) a retrospective view of his research lines, and (ii) a proposal for future studies in the area of the automatic program derivation. The book also includes some papers...

  3. MARZ: Manual and automatic redshifting software

    Science.gov (United States)

    Hinton, S. R.; Davis, Tamara M.; Lidman, C.; Glazebrook, K.; Lewis, G. F.

    2016-04-01

    The Australian Dark Energy Survey (OzDES) is a 100-night spectroscopic survey underway on the Anglo-Australian Telescope using the fibre-fed 2-degree-field (2dF) spectrograph. We have developed a new redshifting application MARZ with greater usability, flexibility, and the capacity to analyse a wider range of object types than the RUNZ software package previously used for redshifting spectra from 2dF. MARZ is an open-source, client-based, Javascript web-application which provides an intuitive interface and powerful automatic matching capabilities on spectra generated from the AAOmega spectrograph to produce high quality spectroscopic redshift measurements. The software can be run interactively or via the command line, and is easily adaptable to other instruments and pipelines if conforming to the current FITS file standard is not possible. Behind the scenes, a modified version of the AUTOZ cross-correlation algorithm is used to match input spectra against a variety of stellar and galaxy templates, and automatic matching performance for OzDES spectra has increased from 54% (RUNZ) to 91% (MARZ). Spectra not matched correctly by the automatic algorithm can be easily redshifted manually by cycling automatic results, manual template comparison, or marking spectral features.

  4. Staple-line leak after sleve gastrectomy in obese patients:A hot topic in bariatric surgery

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Laparoscopic sleeve gastrectomy is a surgical procedurethat is being increasingly performed on obese patients.Among its complications, leaks are the most seriousand life threatening. The placement of esophageal,covered, self-expandable metal stents in these caseshas been performed by many authors but reports on theoutcome of this procedure are limited and the technicalaspects are not well defined. Stent migration is the maincomplication of the procedure and poses a challenge tothe surgeon, with a limited number of options. Here weevaluate the technical and clinical outcome of a new,dedicated, self-expanding metal stent, comparing theadvantages of this stent to those traditionally used totreat staple-line leak after sleeve gastrectomy. Whilepublished data are limited, they seem support the use ofthis kind of new stent as the best option for the stentingtreatment of a staple-line leak after sleeve gastrectomy,over other kinds of stents. Further studies based onlarger series are needed to better evaluate patientoutcome.

  5. VLT Instruments Pipeline System Overview

    Science.gov (United States)

    Jung, Y.; Ballester, P.; Banse, K.; Hummel, W.; Izzo, C.; McKay, D. J.; Kiesgen, M.; Lundin, L. K.; Modigliani, A.; Palsa, R. M.; Sabet, C.

    2004-07-01

    Since the beginning of the VLT operations in 1998, substantial effort has been put in the development of automatic data reduction tools for the VLT instruments. A VLT instrument pipeline is a complex system that has to be able to identify and classify each produced FITS file, optionally retrieve calibration files from a database, use an image processing software to reduce the data, compute and log quality control parameters, produce FITS images or tables with the correct headers, optionally display them in the control room and send them to the archive. Each instrument has its own dedicated pipeline, based on a common infrastructure and installed with the VLT Data Flow System (DFS). With the increase in the number and the complexity of supported instruments and in the rate of produced data, these pipelines are becoming vital for both the VLT operations and the users, and request more and more resources for development and maintenance. This paper describes the different pipeline tasks with some real examples. It also explains how the development process has been improved to both decrease its cost and increase the pipelines quality using the lessons learned from the first instruments pipelines development.

  6. Automatic text summarization

    CERN Document Server

    Torres Moreno, Juan Manuel

    2014-01-01

    This new textbook examines the motivations and the different algorithms for automatic document summarization (ADS). We performed a recent state of the art. The book shows the main problems of ADS, difficulties and the solutions provided by the community. It presents recent advances in ADS, as well as current applications and trends. The approaches are statistical, linguistic and symbolic. Several exemples are included in order to clarify the theoretical concepts.  The books currently available in the area of Automatic Document Summarization are not recent. Powerful algorithms have been develop

  7. Automatic Camera Control

    DEFF Research Database (Denmark)

    Burelli, Paolo; Preuss, Mike

    2014-01-01

    Automatically generating computer animations is a challenging and complex problem with applications in games and film production. In this paper, we investigate howto translate a shot list for a virtual scene into a series of virtual camera configurations — i.e automatically controlling the virtual...... camera. We approach this problem by modelling it as a dynamic multi-objective optimisation problem and show how this metaphor allows a much richer expressiveness than a classical single objective approach. Finally, we showcase the application of a multi-objective evolutionary algorithm to generate a shot...

  8. Porridge deconstructed: a comparative linguistic approach to the history of staple starch food preparations in Bantuphone Africa

    OpenAIRE

    Ricquier, Birgit

    2013-01-01

    Despite the current interest in food studies, little is known about the culinary history of Central and Southern Africa. Using the methods of historical-comparative linguistics, this dissertation provides the first insights into the culinary traditions of early Bantu speech communities. The dissertation focuses on the history of staple starch food preparations, more specifically, the history of porridge and the integration of cassava into Kongo culinary traditions.

  9. Spatial Patterns of Food Staple Production and Marketing in South East Africa: Implications for Trade Policy and Emergency Response

    OpenAIRE

    Haggblade, Steven; Longabaugh, Steven; Tschirley, David L.

    2009-01-01

    This paper aims to develop and test methods for spatial mapping of population, food production, consumption, and marketed quantities in Africa. As an initial, exploratory exercise, the paper examines the spatial pattern of population, food production, consumption, and trade in the three countries of Zambia, Malawi and Mozambique. This largely descriptive initial work will lay the empirical foundations for future analytical work modeling regional trade flows of food staples. By mapping populat...

  10. Physiology and prospects of bimanual tracheoesophageal brass instrument play

    NARCIS (Netherlands)

    Hilgers, F.J.M.; Dirven, R.; Jacobi, I.; van den Brekel, M.W.M.

    2015-01-01

    This study investigated whether trachea pressures during brass instrument play of laryngectomised patients are within the range of those measured during tracheoesophageal voicing, and whether application of an automatic speaking valve can ‘free’ both hands to play a brass instrument. Objective asses

  11. Scraping and stapling of end-grafted DNA chains by a bioadhesive spreading vesicle to reveal chain internal friction and topological complexity.

    Science.gov (United States)

    Nam, Gimoon; Hisette, Marie Laure; Sun, Yuting Liang; Gisler, Thomas; Johner, Albert; Thalmann, Fabrice; Schröder, André Pierre; Marques, Carlos Manuel; Lee, Nam-Kyung

    2010-08-20

    Stained end-grafted DNA molecules about 20 μm long are scraped away and stretched out by the spreading front of a bioadhesive vesicle. Tethered biotin ligands bind the vesicle bilayer to a streptavidin substrate, stapling the DNAs into frozen confinement paths. Image analysis of the stapled DNA gives access, within optical resolution, to the local stretching values of individual DNA molecules swept by the spreading front, and provides evidence of self-entanglements.

  12. Smallholder Heterogeneity and Maize Market Participation in Southern and Eastern Africa: Implications for Investment Strategies to Increase Marketed Food Staple Supply

    OpenAIRE

    Mather, David; Boughton, Duncan; Jayne, Thomas S.

    2011-01-01

    In many African countries, as well as in other parts of the world where a significant part of the rural population is poor and food insecure, policymakers face what is called the food price dilemma. On the one hand, they need to provide farmers with incentives to increase the quantity of marketed food staples to feed a growing population, especially in rapidly growing urban centers where unrest can be politically destabilizing. On the other hand, because staple foods account for a large porti...

  13. Development of Isogenic Restorer Line in Extra Long Staple Cotton Variety Suvin

    Directory of Open Access Journals (Sweden)

    S. Manickam, K. N. Gururajan and N. Gopalakrishnan

    2010-07-01

    Full Text Available Cotton is the most important commercial crop of India and heterosis in cotton is well documented with 7 to 50per cent heterosis in interspecific (G. hirsutum x G. barbadense hybrids, 10 to 138 per cent in intra-hirsutum hybrids andupto 220 per cent in desi (G. herbaceum x G. arboreum hybrids. Currently hybrid cotton, especially Bt cotton hybrids,occupies more than 80 per cent of cultivated area under cotton in India. Male sterility system offers tremendousadvantage to produce quality hybrid seeds at affordable price so that even marginal farmers can take up hybridcultivation. In cotton both GMS and CGMS systems are available. In cotton, two types of male sterility viz., Genic(GMS and Cytoplasmic-Genic (CGMS systems have been identified. Both the systems have been utilized for thecommercial hybrid seed production in India and other countries. In CGMS system, the male parent of the hybrid needsto be converted into Restorer line. In cotton, Suvin is the only extra long staple G. barbadense variety available which iscapable of spinning to 120s count yarn. This variety has been successfully converted into Restorer line through backcross breeding utilizing Pima Restorer as the donor parent. Suvin Restorer is found to stably restore fertility in differentCMS lines of G. hirsutum. The interspecific hybrids developed using Suvin Restorer was found to combine both highyield and superior fibre quality capable of spinning upto 80s count and are comparable with conventional check hybrids.

  14. Chemical synthesis of hydrocarbon-stapled peptides for protein interaction research and therapeutic targeting.

    Science.gov (United States)

    Bird, Gregory H; Crannell, W Christian; Walensky, Loren D

    2011-09-01

    The peptide α-helix represents one of nature's most featured protein shapes and is employed in a diversity of protein architectures, from the cytoskeletal infrastructure to the most intimate contact points between crucial signaling proteins. By installing an all-hydrocarbon crosslink into native sequences, the shape and biological activity of natural peptide α-helices can be recapitulated, yielding a chemical toolbox that can be used both to interrogate the protein interactome and to modulate interaction networks for potential therapeutic benefit. Here, current methodology for synthesizing stabilized α-helices (SAH) corresponding to key protein interaction domains is described. A stepwise approach is taken for the production of crosslinking non-natural amino acids, incorporation of the residues into peptide templates, and application of ruthenium-catalyzed ring-closing metathesis to generate hydrocarbon-stapled peptides. Through facile derivatization and functionalization steps, SAHs can be tailored for a broad range of applications in biochemical, structural, proteomic, cellular, and in vivo studies. Curr. Protoc. Chem. Biol. 3:99-117 © 2011 by John Wiley & Sons, Inc.

  15. Functional outcome after perineal stapled prolapse resection for external rectal prolapse

    Directory of Open Access Journals (Sweden)

    Borovicka Jan

    2010-03-01

    Full Text Available Abstract Background A new surgical technique, the Perineal Stapled Prolapse resection (PSP for external rectal prolapse was introduced in a feasibility study in 2008. This study now presents the first results of a larger patient group with functional outcome in a mid-term follow-up. Methods From December 2007 to April 2009 PSP was performed by the same surgeon team on patients with external rectal prolapse. The prolapse was completely pulled out and then axially cut open with a linear stapler at three and nine o'clock in lithotomy position. Finally, the prolapse was resected stepwise with the curved Contour® Transtar™ stapler at the prolapse's uptake. Perioperative morbidity and functional outcome were prospectively measured by appropriate scores. Results 32 patients participated in the study; median age was 80 years (range 26-93. No intraoperative complications and 6.3% minor postoperative complications occurred. Median operation time was 30 minutes (15-65, hospital stay 5 days (2-19. Functional outcome data were available in 31 of the patients after a median follow-up of 6 months (4-22. Preoperative severe faecal incontinence disappeared postoperatively in 90% of patients with a reduction of the median Wexner score from 16 (4-20 to 1 (0-14 (P Conclusions The PSP is an elegant, fast and safe procedure, with good functional results. Trial registration ISRCTN68491191

  16. Chemical evaluation of multimixes formulated from some local staples for use as complementary foods in Nigeria.

    Science.gov (United States)

    Nnam, N M

    2000-01-01

    The nutrient compositions of eight multimixes formulated for use as complementary foods from processed soybeans, cowpeas, maize, sorghum, yams, cocoyams, plantains and sweet potatoes were examined. The foods were processed by sprouting, cooking and fermentation. The samples were separately dried and milled to fine flours. A ratio of 65% cereal, 30% legume and 5% starchy staple (65:30:5) calculated on a protein basis was used to formulate the multimixes. The blends were chemically analyzed using standard procedures. The mixtures containing soybeans had higher protein, lipid, energy, crude fiber and calcium levels but lower carbohydrate content than those mixtures without soybean. The protein and energy levels of the multimixes were higher than those of some commercial infant foods (Cerelac, Farex and Nestrum) in Nigeria but were comparable to that of 'soy-ogi'. The multimixes contained fair quantities of calcium and phosphorus and an adequate amount of some of the essential amino acids. Methionine was the most limiting amino acid in all the mixtures. Blending cowpeas with maize produced a higher protein score than blending cowpeas or soybeans with sorghum. The cowpea/maize/sweet potato mixture had the highest protein score.

  17. Integrated Approaches for the Management of Staple Line Leaks following Sleeve Gastrectomy

    Directory of Open Access Journals (Sweden)

    Mauro Montuori

    2017-01-01

    Full Text Available Introduction. Aim of the study was trying to draw a final flow chart for the management of gastric leaks after laparoscopic sleeve gastrectomy, based on the review of our cases over 10 years’ experience. Material and Methods. We retrospectively reviewed all patients who underwent LSG as a primary operation at the Bariatric Unit of Tor Vergata University Hospital in Rome from 2007 to 2015. Results. Patients included in the study were 418. There were 6 staple line leaks (1.44%. All patients with diagnosis of a leak were initially discharged home in good clinical conditions and then returned to A&E because of the complication. The mean interval between surgery and readmission for leak was 13,4 days (range 6–34 days, SD ± 11.85. We recorded one death (16.67% due to sepsis. The remaining five cases were successfully treated with a mean healing time of the gastric leak of 55,5 days (range 26–83 days; SD ± 25.44. Conclusion. Choosing the proper treatment depends on clinical stability and on the presence or not of collected abscess. Our treatment protocol showed being associated with low complication rate and minor discomfort to the patients, reducing the need for more invasive procedures.

  18. Vertebral Body Stapling versus Bracing for Patients with High-Risk Moderate Idiopathic Scoliosis

    Science.gov (United States)

    Cuddihy, Laury; Danielsson, Aina J.; Cahill, Patrick J.; Samdani, Amer F.; Grewal, Harsh; Richmond, John M.; Mulcahey, M. J.; Gaughan, John P.; Antonacci, M. Darryl; Betz, Randal R.

    2015-01-01

    Purpose. We report a comparison study of vertebral body stapling (VBS) versus a matched bracing cohort for immature patients with moderate (25 to 44°) idiopathic scoliosis (IS). Methods. 42 of 49 consecutive patients (86%) with IS were treated with VBS and followed for a minimum of 2 years. They were compared to 121 braced patients meeting identical inclusion criteria. 52 patients (66 curves) were matched according to age at start of treatment (10.6 years versus 11.1 years, resp. [P = 0.07]) and gender. Results. For thoracic curves 25–34°, VBS had a success rate (defined as curve progression Risser 0-1) moderate IS (25–44°), in smaller thoracic curves (25–34°) VBS provided better results as a clinical trend as compared to bracing. VBS was found not to be effective for thoracic curves ≥35°. For lumbar curves measuring 25–34°, results appear to be similar for both VBS and bracing, at 80% success. PMID:26618169

  19. Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting.

    Science.gov (United States)

    Wachter, F; Morgan, A M; Godes, M; Mourtada, R; Bird, G H; Walensky, L D

    2016-10-10

    Hydrocarbon-stapled peptides that display key residues of the p53 transactivation domain have emerged as bona fide clinical candidates for reactivating the tumor suppression function of p53 in cancer by dual targeting of the negative regulators HDM2 and HDMX. A recent study questioned the mechanistic specificity of such stapled peptides based on interrogating their capacity to disrupt p53/HDM2 and p53/HDMX complexes in living cells using a new recombinase enhanced bimolecular luciferase complementation platform (ReBiL). Here, we directly evaluate the cellular uptake, intracellular targeting selectivity and p53-dependent cytotoxicity of the clinical prototype ATSP-7041. We find that under standard serum-containing tissue culture conditions, ATSP-7041 achieves intracellular access without membrane disruption, dose-dependently dissociates both p53/HDM2 and p53/HDMX complexes but not an unrelated protein complex in long-term ReBiL experiments, and is selectively cytotoxic to cancer cells bearing wild-type p53 by inducing a surge in p53 protein level. These studies underscore the importance of a thorough stepwise approach, including consideration of the time-dependence of cellular uptake and intracellular distribution, in evaluating and advancing stapled peptides for clinical translation.Oncogene advance online publication, 10 October 2016; doi:10.1038/onc.2016.361.

  20. ON THE STRATEGIC POSITION AND DEVELOPMENT OF THE TRADITIONAL STAPLE FOOD INDUSTRIALIZATION%传统主食战略地位和发展研究

    Institute of Scientific and Technical Information of China (English)

    李里特

    2012-01-01

    Based on the general definition of staple food, the paper analyzes the strategic position and impor- tance of the traditional staple food and elaborates the regionalized features of staple food in combination with some instances. Then it introduces the history and successful experience of the world' s major countries, espe- cially Japan, in staple food industrialization, analyzes the advantages of the traditional Chinese dietary pattern and the history of the staple food industrialization and make recommendations to promote the staple food indus- trialization in China.%在给出主食的一般定义基础上,分析了传统主食的战略地位和重要意义。结合实例阐述了主食的区域化特点。介绍了世界主要国家特别是日本主食产业化的历史和成功经验,分析了我国传统膳食结构的优势和主食工业化的历史,提出我国推进主食产业化的建议。

  1. Automatic Complexity Analysis

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    1989-01-01

    One way to analyse programs is to to derive expressions for their computational behaviour. A time bound function (or worst-case complexity) gives an upper bound for the computation time as a function of the size of input. We describe a system to derive such time bounds automatically using abstract...

  2. Exploring Automatization Processes.

    Science.gov (United States)

    DeKeyser, Robert M.

    1996-01-01

    Presents the rationale for and the results of a pilot study attempting to document in detail how automatization takes place as the result of different kinds of intensive practice. Results show that reaction times and error rates gradually decline with practice, and the practice effect is skill-specific. (36 references) (CK)

  3. An Automatic Engine Analyzer.

    Science.gov (United States)

    Tian-Fu, Li; And Others

    1984-01-01

    Describes an inexpensive, simple, microprocessor-based instrument which quickly and accurately measures and displays the indicated power and the pressure-volume indicator diagram of a reciprocating compressor or internal combustion engine. Hardware requirements, software considerations, and the instrument's educational value are discussed. (JN)

  4. Optical Instruments

    Science.gov (United States)

    1990-01-01

    Precision Lapping and Optical Co. has developed a wide variety of hollow retroreflector systems for applications involving the entire optical spectrum; they are, according to company literature, cheaper, more accurate, lighter and capable of greater size than solid prisms. Precision Lapping's major customers are aerospace and defense companies, government organizations, R&D and commercial instrument companies. For example, Precision Lapping supplies hollow retroreflectors for the laser fire control system of the Army's Abrams tank, and retroreflectors have been and are being used in a number of space tests relative to the Air Force's Strategic Defense Initiative research program. An example of a customer/user is Chesapeake Laser Systems, producer of the Laser Tracker System CMS-2000, which has applications in SDI research and industrial robotics. Another customer is MDA Scientific, Inc., manufacturer of a line of toxic gas detection systems used to monitor hazardous gases present in oil fields, refineries, offshore platforms, chemical plants, waste storage sites and other locations where gases are released into the environment.

  5. Automaticity and Reading: Perspectives from the Instance Theory of Automatization.

    Science.gov (United States)

    Logan, Gordon D.

    1997-01-01

    Reviews recent literature on automaticity, defining the criteria that distinguish automatic processing from non-automatic processing, and describing modern theories of the underlying mechanisms. Focuses on evidence from studies of reading and draws implications from theory and data for practical issues in teaching reading. Suggests that…

  6. Acquisition of Automatic Imitation Is Sensitive to Sensorimotor Contingency

    Science.gov (United States)

    Cook, Richard; Press, Clare; Dickinson, Anthony; Heyes, Cecilia

    2010-01-01

    The associative sequence learning model proposes that the development of the mirror system depends on the same mechanisms of associative learning that mediate Pavlovian and instrumental conditioning. To test this model, two experiments used the reduction of automatic imitation through incompatible sensorimotor training to assess whether mirror…

  7. Preventing SQL Injection through Automatic Query Sanitization with ASSIST

    CERN Document Server

    Mui, Raymond; 10.4204/EPTCS.35.3

    2010-01-01

    Web applications are becoming an essential part of our everyday lives. Many of our activities are dependent on the functionality and security of these applications. As the scale of these applications grows, injection vulnerabilities such as SQL injection are major security challenges for developers today. This paper presents the technique of automatic query sanitization to automatically remove SQL injection vulnerabilities in code. In our technique, a combination of static analysis and program transformation are used to automatically instrument web applications with sanitization code. We have implemented this technique in a tool named ASSIST (Automatic and Static SQL Injection Sanitization Tool) for protecting Java-based web applications. Our experimental evaluation showed that our technique is effective against SQL injection vulnerabilities and has a low overhead.

  8. Examination of the semi-automatic calculation technique of vegetation cover rate by digital camera images.

    Science.gov (United States)

    Takemine, S.; Rikimaru, A.; Takahashi, K.

    The rice is one of the staple foods in the world High quality rice production requires periodically collecting rice growth data to control the growth of rice The height of plant the number of stem the color of leaf is well known parameters to indicate rice growth Rice growth diagnosis method based on these parameters is used operationally in Japan although collecting these parameters by field survey needs a lot of labor and time Recently a laborsaving method for rice growth diagnosis is proposed which is based on vegetation cover rate of rice Vegetation cover rate of rice is calculated based on discriminating rice plant areas in a digital camera image which is photographed in nadir direction Discrimination of rice plant areas in the image was done by the automatic binarization processing However in the case of vegetation cover rate calculation method depending on the automatic binarization process there is a possibility to decrease vegetation cover rate against growth of rice In this paper a calculation method of vegetation cover rate was proposed which based on the automatic binarization process and referred to the growth hysteresis information For several images obtained by field survey during rice growing season vegetation cover rate was calculated by the conventional automatic binarization processing and the proposed method respectively And vegetation cover rate of both methods was compared with reference value obtained by visual interpretation As a result of comparison the accuracy of discriminating rice plant areas was increased by the proposed

  9. Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain

    Directory of Open Access Journals (Sweden)

    Cowburn David

    2011-05-01

    Full Text Available Abstract Background The C-terminal domain (CTD of HIV-1 capsid (CA, like full-length CA, forms dimers in solution and CTD dimerization is a major driving force in Gag assembly and maturation. Mutations of the residues at the CTD dimer interface impair virus assembly and render the virus non-infectious. Therefore, the CTD represents a potential target for designing anti-HIV-1 drugs. Results Due to the pivotal role of the dimer interface, we reasoned that peptides from the α-helical region of the dimer interface might be effective as decoys to prevent CTD dimer formation. However, these small peptides do not have any structure in solution and they do not penetrate cells. Therefore, we used the hydrocarbon stapling technique to stabilize the α-helical structure and confirmed by confocal microscopy that this modification also made these peptides cell-penetrating. We also confirmed by using isothermal titration calorimetry (ITC, sedimentation equilibrium and NMR that these peptides indeed disrupt dimer formation. In in vitro assembly assays, the peptides inhibited mature-like virus particle formation and specifically inhibited HIV-1 production in cell-based assays. These peptides also showed potent antiviral activity against a large panel of laboratory-adapted and primary isolates, including viral strains resistant to inhibitors of reverse transcriptase and protease. Conclusions These preliminary data serve as the foundation for designing small, stable, α-helical peptides and small-molecule inhibitors targeted against the CTD dimer interface. The observation that relatively weak CA binders, such as NYAD-201 and NYAD-202, showed specificity and are able to disrupt the CTD dimer is encouraging for further exploration of a much broader class of antiviral compounds targeting CA. We cannot exclude the possibility that the CA-based peptides described here could elicit additional effects on virus replication not directly linked to their ability to bind

  10. Climate Variability and Yields of Major Staple Food Crops in Northern Ghana

    Science.gov (United States)

    Amikuzuno, J.

    2012-12-01

    Climate variability, the short-term fluctuations in average weather conditions, and agriculture affect each other. Climate variability affects the agroecological and growing conditions of crops and livestock, and is recently believed to be the greatest impediment to the realisation of the first Millennium Development Goal of reducing poverty and food insecurity in arid and semi-arid regions of developing countries. Conversely, agriculture is a major contributor to climate variability and change by emitting greenhouse gases and reducing the agroecology's potential for carbon sequestration. What however, is the empirical evidence of this inter-dependence of climate variability and agriculture in Sub-Sahara Africa? In this paper, we provide some insight into the long run relationship between inter-annual variations in temperature and rainfall, and annual yields of the most important staple food crops in Northern Ghana. Applying pooled panel data of rainfall, temperature and yields of the selected crops from 1976 to 2010 to cointegration and Granger causality models, there is cogent evidence of cointegration between seasonal, total rainfall and crop yields; and causality from rainfall to crop yields in the Sudano-Guinea Savannah and Guinea Savannah zones of Northern Ghana. This suggests that inter-annual yields of the crops have been influenced by the total mounts of rainfall in the planting season. Temperature variability over the study period is however stationary, and is suspected to have minimal effect if any on crop yields. Overall, the results confirm the appropriateness of our attempt in modelling long-term relationships between the climate and crop yield variables.

  11. Transoral treatment of Zenker diverticulum: flexible endoscopy versus endoscopic stapling. A retrospective comparison of outcomes.

    Science.gov (United States)

    Repici, A; Pagano, N; Fumagalli, U; Peracchia, A; Narne, S; Malesci, A; Rosati, R

    2011-05-01

    Transoral stapled diverticulo-esophagostomy (TSDE) has gained increased popularity in surgical treatment of Zenker diverticulum (ZD). One of the advantages of this approach is early rehabilitation with significant decrease in patient morbidity and time to resumption of oral intake as compared with open treatment. The section of the septum between the diverticulum and the esophagus with a flexible endoscopic (ES) approach has also been proposed since mid-90s as an alternative for treatment of ZD. Both these approaches are a minimally invasive approach to treat ZD. We compared the TSDE management of ZD versus the ES treatment in a retrospective consecutive series of patients who were referred to either the ES or surgical unit of our Institute. Fifty-eight consecutive patients underwent treatment for ZD either by TSDE or ES. The two techniques were evaluated for length of hospital stay, diverticulum size, resumption of oral intake, resolution of dysphagia, and complications. Clinical outcome was evaluated throughout a symptom score from 0 to 3, calculated before and after the procedure. The two groups were compared on the various parameters using a Mann--Whitney test. Twenty-eight patients underwent ES and 30 TSDE for ZD. In both groups, a significant decrease in postoperative versus preoperative dysphagia was reported. The average length of hospital stay wasn't significantly different in the two groups (3.38 days for TSDE vs. 2.42 days for ES). The overall complication rate was similar in the two groups. There were two cases in the ES group and three cases in the TDSE group that required an ES revision to take down a residual diverticular wall that produced a mild but persistent dysphagia. Minimally invasive treatment of ZD both with ES and with TSDE is a valuable option for this disease: both techniques are safe and effective, with similar outcome in terms of hospital stay, symptom reduction, and complication rate. Long-term results have to be evaluated.

  12. Projective analysis of staple food crop productivity in adaptation to future climate change in China

    Science.gov (United States)

    Zhang, Qing; Zhang, Wen; Li, Tingting; Sun, Wenjuan; Yu, Yongqiang; Wang, Guocheng

    2017-02-01

    Climate change continually affects our capabilities to feed the increasing population. Rising temperatures have the potential to shorten the crop growth duration and therefore reduce crop yields. In the past decades, China has successfully improved crop cultivars to stabilize, and even lengthen, the crop growth duration to make use of increasing heat resources. However, because of the complex cropping systems in the different regions of China, the possibility and the effectiveness of regulating crop growth duration to reduce the negative impacts of future climate change remain questionable. Here, we performed a projective analysis of the staple food crop productivity in double-rice, wheat-rice, wheat-maize, single-rice, and single-maize cropping systems in China using modeling approaches. The results indicated that from the present to the 2040s, the warming climate would shorten the growth duration of the current rice, wheat, and maize cultivars by 2-24, 11-13, and 9-29 days, respectively. The most significant shortening of the crop growth duration would be in Northeast China, where single-rice and single-maize cropping dominates the croplands. The shortened crop growth duration would consequently reduce crop productivity. The most significant decreases would be 27-31, 6-20, and 7-22% for the late crop in the double-rice rotation, wheat in the winter wheat-rice rotation, and single maize, respectively. However, our projection analysis also showed that the negative effects of the warming climate could be compensated for by stabilizing the growth duration of the crops via improvement in crop cultivars. In this case, the productivity of rice, wheat, and maize in the 2040s would increase by 4-16, 31-38, and 11-12%, respectively. Our modeling results implied that the possibility of securing future food production exists by adopting proper adaptation options in China.

  13. Automaticity or active control

    DEFF Research Database (Denmark)

    Tudoran, Ana Alina; Olsen, Svein Ottar

    aspects of the construct, such as routine, inertia, automaticity, or very little conscious deliberation. The data consist of 2962 consumers participating in a large European survey. The results show that habit strength significantly moderates the association between satisfaction and action loyalty, and......This study addresses the quasi-moderating role of habit strength in explaining action loyalty. A model of loyalty behaviour is proposed that extends the traditional satisfaction–intention–action loyalty network. Habit strength is conceptualised as a cognitive construct to refer to the psychological......, respectively, between intended loyalty and action loyalty. At high levels of habit strength, consumers are more likely to free up cognitive resources and incline the balance from controlled to routine and automatic-like responses....

  14. Automatic Ultrasound Scanning

    DEFF Research Database (Denmark)

    Moshavegh, Ramin

    Medical ultrasound has been a widely used imaging modality in healthcare platforms for examination, diagnostic purposes, and for real-time guidance during surgery. However, despite the recent advances, medical ultrasound remains the most operator-dependent imaging modality, as it heavily relies...... on the user adjustments on the scanner interface to optimize the scan settings. This explains the huge interest in the subject of this PhD project entitled “AUTOMATIC ULTRASOUND SCANNING”. The key goals of the project have been to develop automated techniques to minimize the unnecessary settings...... on the scanners, and to improve the computer-aided diagnosis (CAD) in ultrasound by introducing new quantitative measures. Thus, four major issues concerning automation of the medical ultrasound are addressed in this PhD project. They touch upon gain adjustments in ultrasound, automatic synthetic aperture image...

  15. Automatic trend estimation

    CERN Document Server

    Vamos¸, C˘alin

    2013-01-01

    Our book introduces a method to evaluate the accuracy of trend estimation algorithms under conditions similar to those encountered in real time series processing. This method is based on Monte Carlo experiments with artificial time series numerically generated by an original algorithm. The second part of the book contains several automatic algorithms for trend estimation and time series partitioning. The source codes of the computer programs implementing these original automatic algorithms are given in the appendix and will be freely available on the web. The book contains clear statement of the conditions and the approximations under which the algorithms work, as well as the proper interpretation of their results. We illustrate the functioning of the analyzed algorithms by processing time series from astrophysics, finance, biophysics, and paleoclimatology. The numerical experiment method extensively used in our book is already in common use in computational and statistical physics.

  16. Automatic food decisions

    DEFF Research Database (Denmark)

    Mueller Loose, Simone

    Consumers' food decisions are to a large extent shaped by automatic processes, which are either internally directed through learned habits and routines or externally influenced by context factors and visual information triggers. Innovative research methods such as eye tracking, choice experiments...... and food diaries allow us to better understand the impact of unconscious processes on consumers' food choices. Simone Mueller Loose will provide an overview of recent research insights into the effects of habit and context on consumers' food choices....

  17. New automatic minidisk infiltrometer: design and testing

    Directory of Open Access Journals (Sweden)

    Klípa Vladimír

    2015-06-01

    Full Text Available Soil hydraulic conductivity is a key parameter to predict water flow through the soil profile. We have developed an automatic minidisk infiltrometer (AMI to enable easy measurement of unsaturated hydraulic conductivity using the tension infiltrometer method in the field. AMI senses the cumulative infiltration by recording change in buoyancy force acting on a vertical solid bar fixed in the reservoir tube of the infiltrometer. Performance of the instrument was tested in the laboratory and in two contrasting catchments at three sites with different land use. Hydraulic conductivities determined using AMI were compared with earlier manually taken readings. The results of laboratory testing demonstrated high accuracy and robustness of the AMI measurement. Field testing of AMI proved the suitability of the instrument for use in the determination of sorptivity and near saturated hydraulic conductivity

  18. Automatization of lexicographic work

    Directory of Open Access Journals (Sweden)

    Iztok Kosem

    2013-12-01

    Full Text Available A new approach to lexicographic work, in which the lexicographer is seen more as a validator of the choices made by computer, was recently envisaged by Rundell and Kilgarriff (2011. In this paper, we describe an experiment using such an approach during the creation of Slovene Lexical Database (Gantar, Krek, 2011. The corpus data, i.e. grammatical relations, collocations, examples, and grammatical labels, were automatically extracted from 1,18-billion-word Gigafida corpus of Slovene. The evaluation of the extracted data consisted of making a comparison between the time spent writing a manual entry and a (semi-automatic entry, and identifying potential improvements in the extraction algorithm and in the presentation of data. An important finding was that the automatic approach was far more effective than the manual approach, without any significant loss of information. Based on our experience, we would propose a slightly revised version of the approach envisaged by Rundell and Kilgarriff in which the validation of data is left to lower-level linguists or crowd-sourcing, whereas high-level tasks such as meaning description remain the domain of lexicographers. Such an approach indeed reduces the scope of lexicographer’s work, however it also results in the ability of bringing the content to the users more quickly.

  19. Instrumentation and Controls Division biennial progress report, September 1, 1974--September 1, 1976. Non-LMFBR programs

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)

    1976-11-01

    Research progress and developments are reported in the areas of basic electronics, instruments, radiation monitoring, pulse counting and analysis, electronic engineering support for research facilities, automatic control and data acquisition, reactor instrumentation and controls, fuel reprocessing and shipping, process systems and instrumentation development, thermometry, instrumentation for reactor division experiments and test loops, environmental science studies, miscellaneous engineering studies, services, and developments, and maintenance. (WHK)

  20. Automatic detecting method of LED signal lamps on fascia based on color image

    Science.gov (United States)

    Peng, Xiaoling; Hou, Wenguang; Ding, Mingyue

    2009-10-01

    Instrument display panel is one of the most important parts of automobiles. Automatic detection of LED signal lamps is critical to ensure the reliability of automobile systems. In this paper, an automatic detection method was developed which is composed of three parts in the automatic detection: the shape of LED lamps, the color of LED lamps, and defect spots inside the lamps. More than hundreds of fascias were detected with the automatic detection algorithm. The speed of the algorithm is quite fast and satisfied with the real-time request of the system. Further, the detection result was demonstrated to be stable and accurate.

  1. Maternal consumption of non-staple food in the first trimester and risk of neural tube defects in offspring.

    Science.gov (United States)

    Wang, Meng; Wang, Zhi-Ping; Gao, Li-Jie; Yang, Hui; Zhao, Zhong-Tang

    2015-04-24

    To study the associations between maternal consumption of non-staple food in the first trimester and risk of neural tube defects (NTDs) in offspring. Data collected from a hospital-based case-control study conducted between 2006 and 2008 in Shandong/Shanxi provinces including 459 mothers with NTDs-affected births and 459 mothers without NTDs-affected births. Logistic regression models were used to examine the associations between maternal consumption of non-staple food in the first trimester and risk of NTDs in offspring. The effects were evaluated by odds ratio (OR) and 95% confidence intervals (95% CIs) with SAS9.1.3.software. Maternal consumption of milk, fresh fruits and nuts in the first trimester were protective factors for total NTDs. Compared with consumption frequency of ˂1 meal/week, the ORs for milk consumption frequency of 1-2, 3-6, ≥7 meals/week were 0.50 (95% CI: 0.28-0.88), 0.56 (0.32-0.99), and 0.59 (0.38-0.90), respectively; the ORs for fresh fruits consumption frequency of 1-2, 3-6, ≥7 meals/week were 0.29 (95% CI: 0.12-0.72), 0.22 (0.09-0.53), and 0.32 (0.14-0.71), respectively; the ORs for nuts consumption frequency of 1-2, 3-6, ≥7 meals/week were 0.60 (95% CI: 0.38-0.94), 0.49 (0.31-0.79), and 0.63 (0.36-1.08), respectively. Different effects of above factors on NTDs were found for subtypes of anencephaly and spina bifida. Maternal non-staple food consumption of milk, fresh fruits and nuts in the first trimester was associated with reducing NTDs risk in offspring.

  2. Instrumentation and Controls Division biennial progress report, September 1, 1976--September 1, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (ed.)

    1978-11-01

    Progress is summarized in the following research and development areas: electronic circuits;instruments; radiation monitoring; process systems and instrumentation; thermometry; instrumentation for engineering experiments and test loops; HTGR fuel recycle development; reactor measurements and analysis; automatic control and data acquisition; electronic engineering support for research facilities; miscellaneous engineering services, studies, and developments; maintenance; and environmental science studies.

  3. Evolutionary programming for neutron instrument optimisation

    Energy Technology Data Exchange (ETDEWEB)

    Bentley, Phillip M. [Hahn-Meitner Institut, Glienicker Strasse 100, D-14109 Berlin (Germany)]. E-mail: phillip.bentley@hmi.de; Pappas, Catherine [Hahn-Meitner Institut, Glienicker Strasse 100, D-14109 Berlin (Germany); Habicht, Klaus [Hahn-Meitner Institut, Glienicker Strasse 100, D-14109 Berlin (Germany); Lelievre-Berna, Eddy [Institut Laue-Langevin, 6 rue Jules Horowitz, BP 156, 38042 Grenoble Cedex 9 (France)

    2006-11-15

    Virtual instruments based on Monte-Carlo techniques are now integral part of novel instrumentation development and the existing codes (McSTAS and Vitess) are extensively used to define and optimise novel instrumental concepts. Neutron spectrometers, however, involve a large number of parameters and their optimisation is often a complex and tedious procedure. Artificial intelligence algorithms are proving increasingly useful in such situations. Here, we present an automatic, reliable and scalable numerical optimisation concept based on the canonical genetic algorithm (GA). The algorithm was used to optimise the 3D magnetic field profile of the NSE spectrometer SPAN, at the HMI. We discuss the potential of the GA which combined with the existing Monte-Carlo codes (Vitess, McSTAS, etc.) leads to a very powerful tool for automated global optimisation of a general neutron scattering instrument, avoiding local optimum configurations.

  4. Evolutionary programming for neutron instrument optimisation

    Science.gov (United States)

    Bentley, Phillip M.; Pappas, Catherine; Habicht, Klaus; Lelièvre-Berna, Eddy

    2006-11-01

    Virtual instruments based on Monte-Carlo techniques are now integral part of novel instrumentation development and the existing codes (McSTAS and Vitess) are extensively used to define and optimise novel instrumental concepts. Neutron spectrometers, however, involve a large number of parameters and their optimisation is often a complex and tedious procedure. Artificial intelligence algorithms are proving increasingly useful in such situations. Here, we present an automatic, reliable and scalable numerical optimisation concept based on the canonical genetic algorithm (GA). The algorithm was used to optimise the 3D magnetic field profile of the NSE spectrometer SPAN, at the HMI. We discuss the potential of the GA which combined with the existing Monte-Carlo codes (Vitess, McSTAS, etc.) leads to a very powerful tool for automated global optimisation of a general neutron scattering instrument, avoiding local optimum configurations.

  5. Surgical staple as a transcutaneous transducer for ECG electrodes in burnt skin: safe surgical monitoring in major burns.

    Science.gov (United States)

    Sofos, Stratos S; Tehrani, Hamid; Shokrollahi, Kayvan; James, M I

    2013-06-01

    It is often difficult to apply traditional ECG electrodes on patients with extensive burns due to a large operative site, compromise of sterility, the fact that traditional placement would be within the operative site or because stick-on pads cannot stick due to prep solution, bleeding and other factors. We present an effective solution based on our experience, of using a common staple or "clip" where the ECG electrode is attached. We can see the patient in the prone position with the back having been debrided and grafted. This technical improvisation gives clinicians the ability to monitor safely and accurately the patients' physiological parameters.

  6. Surgical instrument similarity metrics and tray analysis for multi-sensor instrument identification

    Science.gov (United States)

    Glaser, Bernhard; Schellenberg, Tobias; Franke, Stefan; Dänzer, Stefan; Neumuth, Thomas

    2015-03-01

    A robust identification of the instrument currently used by the surgeon is crucial for the automatic modeling and analysis of surgical procedures. Various approaches for intra-operative surgical instrument identification have been presented, mostly based on radio-frequency identification (RFID) or endoscopic video analysis. A novel approach is to identify the instruments on the instrument table of the scrub nurse with a combination of video and weight information. In a previous article, we successfully followed this approach and applied it to multiple instances of an ear, nose and throat (ENT) procedure and the surgical tray used therein. In this article, we present a metric for the suitability of the instruments of a surgical tray for identification by video and weight analysis and apply it to twelve trays of four different surgical domains (abdominal surgery, neurosurgery, orthopedics and urology). The used trays were digitized at the central sterile services department of the hospital. The results illustrate that surgical trays differ in their suitability for the approach. In general, additional weight information can significantly contribute to the successful identification of surgical instruments. Additionally, for ten different surgical instruments, ten exemplars of each instrument were tested for their weight differences. The samples indicate high weight variability in instruments with identical brand and model number. The results present a new metric for approaches aiming towards intra-operative surgical instrument detection and imply consequences for algorithms exploiting video and weight information for identification purposes.

  7. Automatic Configuration in NTP

    Institute of Scientific and Technical Information of China (English)

    Jiang Zongli(蒋宗礼); Xu Binbin

    2003-01-01

    NTP is nowadays the most widely used distributed network time protocol, which aims at synchronizing the clocks of computers in a network and keeping the accuracy and validation of the time information which is transmitted in the network. Without automatic configuration mechanism, the stability and flexibility of the synchronization network built upon NTP protocol are not satisfying. P2P's resource discovery mechanism is used to look for time sources in a synchronization network, and according to the network environment and node's quality, the synchronization network is constructed dynamically.

  8. Automatic Test Case Generation of C Program Using CFG

    Directory of Open Access Journals (Sweden)

    Sangeeta Tanwer

    2010-07-01

    Full Text Available Software quality and assurance in a software company is the only way to gain the customer confidence by removing all possible errors. It can be done by automatic test case generation. Taking popularly C programs as tests object, this paper explores how to create CFG of a C program and generate automatic Test Cases. It explores the feasibility and nonfeasibility of path basis upon no. of iteration. First C is code converted to instrumented code. Then test cases are generated by using Symbolic Testing and random Testing. System is developed by using C#.net in Visual Studio 2008. In addition some future research directions are also explored.

  9. Evaluating musical instruments

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, D. Murray

    2014-04-01

    Scientific measurements of sound generation and radiation by musical instruments are surprisingly hard to correlate with the subtle and complex judgments of instrumental quality made by expert musicians.

  10. Are biofortified staple food crops improving vitamin A and iron status in women and children? New evidence from efficacy trials.

    Science.gov (United States)

    De Moura, Fabiana F; Palmer, Amanda C; Finkelstein, Julia L; Haas, Jere D; Murray-Kolb, Laura E; Wenger, Michael J; Birol, Ekin; Boy, Erick; Peña-Rosas, Juan Pablo

    2014-09-01

    Biofortification is the breeding of crops to increase their nutritional value, including increased contents of micronutrients or their precursors. Biofortification aims to increase nutrient levels in crops during plant growth rather than during processing of the crops into foods. Emerging research from 8 human trials conducted in the past decade with staple food crops that have been biofortified by traditional plant breeding methods were presented in this symposium. Specifically, data from 6 efficacy and 2 effectiveness trials were discussed to assess the effects of regular consumption of these enhanced staple crops on improving population vitamin A and iron status and reducing the burden of micronutrient deficiencies in targeted populations living in South Asia, Sub-Saharan Africa, and Latin America. Biofortified food crops appear to have a positive impact on nutritional and functional health outcomes, as the results from the trials suggest. Additional implementation research will be needed to ensure maximization of the beneficial impact of this intervention and a smooth scaling up to make biofortification a sustainable intervention in public health. The challenge for the global health community remains how to take this efficacious intervention and implement at large scale in the real world.

  11. Comparison of automatic control systems

    Science.gov (United States)

    Oppelt, W

    1941-01-01

    This report deals with a reciprocal comparison of an automatic pressure control, an automatic rpm control, an automatic temperature control, and an automatic directional control. It shows the difference between the "faultproof" regulator and the actual regulator which is subject to faults, and develops this difference as far as possible in a parallel manner with regard to the control systems under consideration. Such as analysis affords, particularly in its extension to the faults of the actual regulator, a deep insight into the mechanism of the regulator process.

  12. Automatic tuning of myoelectric prostheses.

    Science.gov (United States)

    Bonivento, C; Davalli, A; Fantuzzi, C; Sacchetti, R; Terenzi, S

    1998-07-01

    This paper is concerned with the development of a software package for the automatic tuning of myoelectric prostheses. The package core consists of Fuzzy Logic Expert Systems (FLES) that embody skilled operator heuristics in the tuning of prosthesis control parameters. The prosthesis system is an artificial arm-hand system developed at the National Institute of Accidents at Work (INAIL) laboratories. The prosthesis is powered by an electric motor that is controlled by a microprocessor using myoelectric signals acquired from skin-surface electrodes placed on a muscle in the residual limb of the subject. The software package, Microprocessor Controlled Arm (MCA) Auto Tuning, is a tool for aiding both INAIL expert operators and unskilled persons in the controller parameter tuning procedure. Prosthesis control parameter setup and subsequent recurrent adjustments are fundamental for the correct working of the prosthesis, especially when we consider that myoelectric parameters may vary greatly with environmental modifications. The parameter adjustment requires the end-user to go to the manufacturer's laboratory for the control parameters setup because, generally, he/she does not have the necessary knowledge and instruments to do this at home. However, this procedure is not very practical and involves a waste of time for the technicians and uneasiness for the clients. The idea behind the MCA Auto Tuning package consists in translating technician expertise into an FLES knowledge database. The software interacts through a user-friendly graphic interface with an unskilled user, who is guided through a step-by-step procedure in the prosthesis parameter tuning that emulates the traditional expert-aided procedure. The adoption of this program on a large scale may yield considerable economic benefits and improve the service quality supplied to the users of prostheses. In fact, the time required to set the prosthesis parameters are remarkably reduced, as is the technician

  13. Automatic Fixture Planning

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Fixture planning is a crucial problem in the field of fixture design. In this paper, the research scope and research methods of the computer-aided fixture planning are presented. Based on positioning principles of typical workparts, an ANN algorithm, namely Hopfield algorithm, is adopted for the automatic fixture planning. Also, this paper leads a deep research into the selection of positioning and clamping surfaces (or points) on workparts using positioning-clamping-surface-selecting rules and matrix evaluation of deterministic workpart positioning. In the end of this paper, the methods to select positioning and clamping elements from database and the layout algorithm to assemble the selected fixture elements into a tangible fixture are developed.

  14. IOT Overview: IR Instruments

    Science.gov (United States)

    Mason, E.

    In this instrument review chapter the calibration plans of ESO IR instruments are presented and briefly reviewed focusing, in particular, on the case of ISAAC, which has been the first IR instrument at VLT and whose calibration plan served as prototype for the coming instruments.

  15. Laboratory evaluation of the Boehringer Mannheim "Hitachi 705" automatic analyzer.

    Science.gov (United States)

    Kineiko, R W; Floering, D A; Morrissey, M

    1983-04-01

    We evaluated a new multi-channel chemistry analyzer, the Hitachi 705 Automatic Analyzer, marketed by Boehringer Mannheim Diagnostics, Inc. The instrument is a computer-controlled discrete analyzer, which can be run in a combination profile mode and single-test mode. Sixteen different tests per sample may be performed at the rate of 180 tests per hour. The Hitachi 705 is especially suitable for use in hospitals that do not perform profile testing. Precision and linearity were excellent and the instrument was relatively trouble-free, with little operator attention required during operation. The Hitachi 705 was easily interfaced to our laboratory computer. We compared the performance of the instrument with that of the Du Pont aca; the two instruments compared favorably.

  16. Maternal Consumption of Non-Staple Food in the First Trimester and Risk of Neural Tube Defects in Offspring

    Directory of Open Access Journals (Sweden)

    Meng Wang

    2015-04-01

    Full Text Available To study the associations between maternal consumption of non-staple food in the first trimester and risk of neural tube defects (NTDs in offspring. Data collected from a hospital-based case-control study conducted between 2006 and 2008 in Shandong/Shanxi provinces including 459 mothers with NTDs-affected births and 459 mothers without NTDs-affected births. Logistic regression models were used to examine the associations between maternal consumption of non-staple food in the first trimester and risk of NTDs in offspring. The effects were evaluated by odds ratio (OR and 95% confidence intervals (95% CIs with SAS9.1.3.software. Maternal consumption of milk, fresh fruits and nuts in the first trimester were protective factors for total NTDs. Compared with consumption frequency of ˂1 meal/week, the ORs for milk consumption frequency of 1–2, 3–6, ≥7 meals/week were 0.50 (95% CI: 0.28–0.88, 0.56 (0.32–0.99, and 0.59 (0.38–0.90, respectively; the ORs for fresh fruits consumption frequency of 1–2, 3–6, ≥7 meals/week were 0.29 (95% CI: 0.12–0.72, 0.22 (0.09–0.53, and 0.32 (0.14–0.71, respectively; the ORs for nuts consumption frequency of 1–2, 3–6, ≥7 meals/week were 0.60 (95% CI: 0.38–0.94, 0.49 (0.31–0.79, and 0.63 (0.36–1.08, respectively. Different effects of above factors on NTDs were found for subtypes of anencephaly and spina bifida. Maternal non-staple food consumption of milk, fresh fruits and nuts in the first trimester was associated with reducing NTDs risk in offspring.

  17. Automatic Inspection Of Heat Seals Between Plastic Sheets

    Science.gov (United States)

    Rai, Kula R.; Lew, Thomas M.; Sinclair, Robert B.

    1995-01-01

    Automatic inspection apparatus detects flaws in heat seals between films of polyethylene or other thermoplastic material. Heat-sealed strip in multilayer plastic sheet continuously moved lengthwise over illuminators. Variations in light transmitted through sheet interpreted to find flaws in heat seal. Site of flaw marked to facilitate subsequent manual inspection. Heat sealing used to join plastic films in manufacturing of variety of products, including inflatable toys and balloons carrying scientific instruments to high altitudes.

  18. A fully automatic system for acid-base coulometric titrations

    OpenAIRE

    1990-01-01

    An automatic system for acid-base titrations by electrogeneration of H+ and OH- ions, with potentiometric end-point detection, was developed. The system includes a PC-compatible computer for instrumental control, data acquisition and processing, which allows up to 13 samples to be analysed sequentially with no human intervention. The system performance was tested on the titration of standard solutions, which it carried out with low errors and RSD. It was subsequently applied to the analysis o...

  19. Flexible Automatic Scheduling For Autonomous Telescopes The MAJORDOME

    CERN Document Server

    Bringer, M; Peignot, C; Fontan, G; Merce, C

    2001-01-01

    We have developped a new method for the scheduling of astronomical automatic telescopes, in the framework of the autonomous TAROT instrument. The MAJORDOME software can handle a variety of observations, constrained, periodic, etc., and produces a timeline for the night, which may be modified at any time to take into account the specific conditions of the night. The MAJORDOME can also handle target of opportunity observations without delay.

  20. Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment

    NARCIS (Netherlands)

    Slootweg, Jack C.; Peters, Nienke; Quarles Van Ufford, H. C.; Breukink, Eefjan; Liskamp, Rob M J; Rijkers, Dirk T S

    2014-01-01

    The antimicrobial peptide nisin is a promising template for designing novel peptide-based antibiotics to improve its drug-like properties. First steps in that direction represent the synthesis of hybrid nisin derivatives that contain a native nisin ABC-part and synthesized cross-stapled DE-ring frag

  1. Diagnosis of a submucosal mass at the staple line after sigmoid colon cancer resection by endoscopic cuttingmucosa biopsy

    Institute of Scientific and Technical Information of China (English)

    Mitsuaki Morimoto; Koji Koinuma; Alan K Lefor; Hisanaga Horie; Homare Ito; Naohiro Sata; Yoshikazu Hayashi; Keijiro Sunada; Hironori Yamamoto

    2016-01-01

    A 48-year-old man underwent laparoscopic sigmoid colon resection for cancer and surveillance colonoscopy was performed annually thereafter. Five years after the resection, a submucosal mass was found at the anastomotic staple line, 15 cm from the anal verge. Computed tomography scan and endoscopic ultrasound were not consistent with tumor recurrence. Endoscopic mucosa biopsy was performed to obtain a definitive diagnosis. Mucosal incision over the lesion with the cutting needle knife technique revealed a creamy white material, which was completely removed. Histologic examination showed fibrotic tissue without caseous necrosis or tumor cells. No bacteria, including mycobacterium, were found on culture. The patient remains free of recurrence at five years since the resection. Endoscopic biopsy with a cutting mucosal incision is an important technique for evaluation of submucosal lesions after rectal resection.

  2. IS MASTICATORY FORCE AT MOLAR REGION ANALOGICAL TO STAPLING MECHANICS AND BOTH BELONGING TO AN UNIDENTIFIED LEVER SYSTEM?

    Directory of Open Access Journals (Sweden)

    R.Vinodh Rajkumar

    2014-11-01

    Full Text Available For easy and clear understanding of biomechanics, the inter-relationships of simple machines and musculoskeletal functions have always been attempted and established. The masticatory biomechanics is still under research because there is wide range of findings on masticatory muscles including the lack of complete clarity on their line of actions and lever arms too. As a prospective contribution to advanced research on mastication and management of Temporomandibular joint, there are two innovative concepts discussed in this article; (1 Strong correlation between stapling mechanics and Temporomandibular joint at molar region (2 Scope for a new unidentified lever system named as fourth class lever. The principal intent of this article is to share these two innovative concepts to be explored further for practical applications in the field of Physical therapy, Dentistry and Engineering.

  3. Automatic aircraft recognition

    Science.gov (United States)

    Hmam, Hatem; Kim, Jijoong

    2002-08-01

    Automatic aircraft recognition is very complex because of clutter, shadows, clouds, self-occlusion and degraded imaging conditions. This paper presents an aircraft recognition system, which assumes from the start that the image is possibly degraded, and implements a number of strategies to overcome edge fragmentation and distortion. The current vision system employs a bottom up approach, where recognition begins by locating image primitives (e.g., lines and corners), which are then combined in an incremental fashion into larger sets of line groupings using knowledge about aircraft, as viewed from a generic viewpoint. Knowledge about aircraft is represented in the form of whole/part shape description and the connectedness property, and is embedded in production rules, which primarily aim at finding instances of the aircraft parts in the image and checking the connectedness property between the parts. Once a match is found, a confidence score is assigned and as evidence in support of an aircraft interpretation is accumulated, the score is increased proportionally. Finally a selection of the resulting image interpretations with the highest scores, is subjected to competition tests, and only non-ambiguous interpretations are allowed to survive. Experimental results demonstrating the effectiveness of the current recognition system are given.

  4. Automatic Kurdish Dialects Identification

    Directory of Open Access Journals (Sweden)

    Hossein Hassani

    2016-02-01

    Full Text Available Automatic dialect identification is a necessary Lan guage Technology for processing multi- dialect languages in which the dialects are linguis tically far from each other. Particularly, this becomes crucial where the dialects are mutually uni ntelligible. Therefore, to perform computational activities on these languages, the sy stem needs to identify the dialect that is the subject of the process. Kurdish language encompasse s various dialects. It is written using several different scripts. The language lacks of a standard orthography. This situation makes the Kurdish dialectal identification more interesti ng and required, both form the research and from the application perspectives. In this research , we have applied a classification method, based on supervised machine learning, to identify t he dialects of the Kurdish texts. The research has focused on two widely spoken and most dominant Kurdish dialects, namely, Kurmanji and Sorani. The approach could be applied to the other Kurdish dialects as well. The method is also applicable to the languages which are similar to Ku rdish in their dialectal diversity and differences.

  5. MARZ: Manual and Automatic Redshifting Software

    CERN Document Server

    Hinton, Samuel R; Lidman, Chris; Glazebrook, Karl; Lewis, Geraint F

    2016-01-01

    The Australian Dark Energy Survey (OzDES) is a 100-night spectroscopic survey underway on the Anglo-Australian Telescope using the fibre-fed 2-degree-field (2dF) spectrograph. We have developed a new redshifting application Marz with greater usability, flexibility, and the capacity to analyse a wider range of object types than the Runz software package previously used for redshifting spectra from 2dF. Marz is an open-source, client-based, Javascript web-application which provides an intuitive interface and powerful automatic matching capabilities on spectra generated from the AAOmega spectrograph to produce high quality spectroscopic redshift measurements. The software can be run interactively or via the command line, and is easily adaptable to other instruments and pipelines if conforming to the current FITS file standard is not possible. Behind the scenes, a modified version of the Autoz cross-correlation algorithm is used to match input spectra against a variety of stellar and galaxy templates, and automat...

  6. Electronic amplifiers for automatic compensators

    CERN Document Server

    Polonnikov, D Ye

    1965-01-01

    Electronic Amplifiers for Automatic Compensators presents the design and operation of electronic amplifiers for use in automatic control and measuring systems. This book is composed of eight chapters that consider the problems of constructing input and output circuits of amplifiers, suppression of interference and ensuring high sensitivity.This work begins with a survey of the operating principles of electronic amplifiers in automatic compensator systems. The succeeding chapters deal with circuit selection and the calculation and determination of the principal characteristics of amplifiers, as

  7. The Automatic Telescope Network (ATN)

    CERN Document Server

    Mattox, J R

    1999-01-01

    Because of the scheduled GLAST mission by NASA, there is strong scientific justification for preparation for very extensive blazar monitoring in the optical bands to exploit the opportunity to learn about blazars through the correlation of variability of the gamma-ray flux with flux at lower frequencies. Current optical facilities do not provide the required capability.Developments in technology have enabled astronomers to readily deploy automatic telescopes. The effort to create an Automatic Telescope Network (ATN) for blazar monitoring in the GLAST era is described. Other scientific applications of the networks of automatic telescopes are discussed. The potential of the ATN for science education is also discussed.

  8. Comparison between stainless steel staples and silk sutures for primary closure of skin in patients undergoing neck dissection: A comparative clinical study

    Directory of Open Access Journals (Sweden)

    Abhishek Ghosh

    2015-01-01

    Full Text Available Introduction: Comparison between stainless steel staples and silk sutures for primary closure of skin in patients undergoing neck dissection, in context of rapid application, approximation of the skin edges, economy and aesthetics of the resultant scar. Aim: (1 To compare surgical stainless steel staples and silk sutures for primary wound closure, with respect to presence/absence of wound infection and dehiscence (2 To compare the resultant scar following the two different methods of the closure at 3 rd month postoperatively with the help of visual analog scale and analyze the result statistically Design: This study was designed to compare skin closure using staples and silk sutures in patients undergoing neck dissection, using both methods in one-half of the same wound; thus each wound affording its own control. Materials and Methods: The study was conducted on patients requiring collar line incision (high submandibular incision with or without a cephalad extension of midline lower lip split incision for surgical access, who presented to the Department of Oral and Maxillo-Facial Surgery. (1 Sample size: 10 (2 Study design: Prospective Comparative study (3 Study duration: One and half years (4 Surgical stainless steel staples: Proximate Plus MD 35 W, Ethicon Endo Surgery (5 Sutures: 3-0 Ethiprime NW 5003, Non-Absorbable Surgical Suture, Mersilk-90 cm, Ethicon, (16 mm 3/8 circle cutting needle. Conclusion: It wass concluded that there is no significant difference between the scars observed in the regions of incision which underwent primary closure by two different methods, that is surgical stainless steel staples and 3-0 Mersilk Sutures.

  9. Musical Instrument Identification using Multiscale Mel-frequency Cepstral Coefficients

    DEFF Research Database (Denmark)

    Sturm, Bob L.; Morvidone, Marcela; Daudet, Laurent

    2010-01-01

    We investigate the benefits of evaluating Mel-frequency cepstral coefficients (MFCCs) over several time scales in the context of automatic musical instrument identification for signals that are monophonic but derived from real musical settings. We define several sets of features derived from MFCCs...

  10. Clothes Dryer Automatic Termination Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    TeGrotenhuis, Ward E.

    2014-10-01

    Volume 2: Improved Sensor and Control Designs Many residential clothes dryers on the market today provide automatic cycles that are intended to stop when the clothes are dry, as determined by the final remaining moisture content (RMC). However, testing of automatic termination cycles has shown that many dryers are susceptible to over-drying of loads, leading to excess energy consumption. In particular, tests performed using the DOE Test Procedure in Appendix D2 of 10 CFR 430 subpart B have shown that as much as 62% of the energy used in a cycle may be from over-drying. Volume 1 of this report shows an average of 20% excess energy from over-drying when running automatic cycles with various load compositions and dryer settings. Consequently, improving automatic termination sensors and algorithms has the potential for substantial energy savings in the U.S.

  11. Instrument Modeling and Synthesis

    Science.gov (United States)

    Horner, Andrew B.; Beauchamp, James W.

    During the 1970s and 1980s, before synthesizers based on direct sampling of musical sounds became popular, replicating musical instruments using frequency modulation (FM) or wavetable synthesis was one of the “holy grails” of music synthesis. Synthesizers such as the Yamaha DX7 allowed users great flexibility in mixing and matching sounds, but were notoriously difficult to coerce into producing sounds like those of a given instrument. Instrument design wizards practiced the mysteries of FM instrument design.

  12. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    provides the performer extensive virtuoso capabilities in terms of instrumental range, harmony, timbre, or spatial, textural, acoustic, technical, or technological qualities. The discussion will be illustrated by a composition case study involving augmented musical instrument electromagnetic resonator......The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...

  13. Automatic Coarse Graining of Polymers

    OpenAIRE

    Faller, Roland

    2003-01-01

    Several recently proposed semi--automatic and fully--automatic coarse--graining schemes for polymer simulations are discussed. All these techniques derive effective potentials for multi--atom units or super--atoms from atomistic simulations. These include techniques relying on single chain simulations in vacuum and self--consistent optimizations from the melt like the simplex method and the inverted Boltzmann method. The focus is on matching the polymer structure on different scales. Several ...

  14. Automatic Sarcasm Detection: A Survey

    OpenAIRE

    Joshi, Aditya; Bhattacharyya, Pushpak; Carman, Mark James

    2016-01-01

    Automatic sarcasm detection is the task of predicting sarcasm in text. This is a crucial step to sentiment analysis, considering prevalence and challenges of sarcasm in sentiment-bearing text. Beginning with an approach that used speech-based features, sarcasm detection has witnessed great interest from the sentiment analysis community. This paper is the first known compilation of past work in automatic sarcasm detection. We observe three milestones in the research so far: semi-supervised pat...

  15. Prospects for de-automatization.

    Science.gov (United States)

    Kihlstrom, John F

    2011-06-01

    Research by Raz and his associates has repeatedly found that suggestions for hypnotic agnosia, administered to highly hypnotizable subjects, reduce or even eliminate Stroop interference. The present paper sought unsuccessfully to extend these findings to negative priming in the Stroop task. Nevertheless, the reduction of Stroop interference has broad theoretical implications, both for our understanding of automaticity and for the prospect of de-automatizing cognition in meditation and other altered states of consciousness.

  16. The automatization of journalistic narrative

    Directory of Open Access Journals (Sweden)

    Naara Normande

    2013-06-01

    Full Text Available This paper proposes an initial discussion about the production of automatized journalistic narratives. Despite being a topic discussed in specialized sites and international conferences in communication area, the concepts are still deficient in academic research. For this article, we studied the concepts of narrative, databases and algorithms, indicating a theoretical trend that explains this automatized journalistic narratives. As characterization, we use the cases of Los Angeles Times, Narrative Science and Automated Insights.

  17. Process automatization in system administration

    OpenAIRE

    Petauer, Janja

    2013-01-01

    The aim of the thesis is to present automatization of user management in company Studio Moderna. The company has grown exponentially in recent years, that is why we needed to find faster, easier and cheaper way of man- aging user accounts. We automatized processes of creating, changing and removing user accounts within Active Directory. We prepared user interface inside of existing application, used Java Script for drop down menus, wrote script in scripting programming langu...

  18. Aeroacoustics of Musical Instruments

    NARCIS (Netherlands)

    Fabre, B.; Gilbert, J.; Hirschberg, A.; Pelorson, X.

    2012-01-01

    We are interested in the quality of sound produced by musical instruments and their playability. In wind instruments, a hydrodynamic source of sound is coupled to an acoustic resonator. Linear acoustics can predict the pitch of an instrument. This can significantly reduce the trial-and-error process

  19. Automatic proximate analyzer of coal based on isothermal thermogravimetric analysis (TGA) with twin-furnace

    Energy Technology Data Exchange (ETDEWEB)

    Xiong, Youhui; Jiang, Taiyi; Zou, Xianhong [National Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China)

    2003-12-17

    A new type of rapid and automatic proximate analyzer for coal based on isothermal thermogravimetric analysis (TGA) with twin-furnace is introduced in this paper. This automatic proximate analyzer was developed by combination with some novel technologies, such as the automatic weighting method for multi-samples in a high temperature and dynamic gas flow circumstance, the self-protection system for the electric balance, and the optimal method and procedure for coal analysis process. Additionally, the comparison between standard values and the measurement values derived from the new instrument of standard coals was presented.

  20. Complete approach to automatic identification and subpixel center location for ellipse feature

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    To meet the need of automatic image features extraction with high precision in visual inspection, a complete approach to automatic identification and sub-pixel center location for similar-ellipse feature is proposed. In the method, the feature area is identified automatically based on the edge attribute, and the sub-pixel center location is accomplished with the leastsquare algorithm. It shows that the method is valid, practical, and has high precision by experiment. Meanwhile this method can meet the need of instrumentation of visual inspection because of easy realization and without man-machine interaction.

  1. SPHOTOM - Package for an Automatic Multicolour Photometry

    Science.gov (United States)

    Parimucha, Š.; Vaňko, M.; Mikloš, P.

    2012-04-01

    We present basic information about package SPHOTOM for an automatic multicolour photometry. This package is in development for the creation of a photometric pipe-line, which we plan to use in the near future with our new instruments. It could operate in two independent modes, (i) GUI mode, in which the user can select images and control functions of package through interface and (ii) command line mode, in which all processes are controlled using a main parameter file. SPHOTOM is developed as a universal package for Linux based systems with easy implementation for different observatories. The photometric part of the package is based on the Sextractor code, which allows us to detect all objects on the images and perform their photometry with different apertures. We can also perform astrometric solutions for all images for a correct cross-identification of the stars on the images. The result is a catalogue of all objects with their instrumental photometric measurements which are consequently used for a differential magnitudes calculations with one or more comparison stars, transformations to an international system, and determinations of colour indices.

  2. An optical toolbox for astronomical instrumentation

    Science.gov (United States)

    Sutin, Brian M.

    2016-08-01

    The author has open-sourced a program for optical modeling of astronomical instrumentation. The code allows for optical systems to be described in a programming language. An optical prescription may contain coordinate systems and transformations, arbitrary polynomial aspheric surfaces and complex volumes. Rather than using a plethora of rays to evaluate performance, all the derivatives along a ray are computed by automatic differentiation. By adaptively controlling the patches around each ray, the system can be modeled to a guaranteed known precision. The code currently consists of less than 10,000 lines of C++/stdlib code.

  3. A study of fuel failure behavior in high burnup HTGR fuel. Analysis by STRESS3 and STAPLE codes

    Energy Technology Data Exchange (ETDEWEB)

    Martin, David G.; Sawa, Kazuhiro; Ueta, Shouhei; Sumita, Junya [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    2001-05-01

    In current high temperature gas-cooled reactors (HTGRs), Tri-isotropic coated fuel particles are employed as fuel. In safety design of the HTGR fuels, it is important to retain fission products within particles so that their release to primary coolant does not exceed an acceptable level. From this point of view, the basic design criteria for the fuel are to minimize the failure fraction of as-fabricated fuel coating layers and to prevent significant additional fuel failures during operation. This report attempts to model fuel behavior in irradiation tests using the U.K. codes STRESS3 and STAPLE. Test results in 91F-1A and HRB-22 capsules irradiation tests, which were carried out at the Japan Materials Testing Reactor of JAERI and at the High Flux Isotope Reactor of Oak Ridge National Laboratory, respectively, were employed in the calculation. The maximum burnup and fast neutron fluence were about 10%FIMA and 3 x 10{sup 25} m{sup -2}, respectively. The fuel for the irradiation tests was called high burnup fuel, whose target burnup and fast neutron fluence were higher than those of the first-loading fuel of the High Temperature Engineering Test Reactor. The calculation results demonstrated that if only mean fracture stress values of PyC and SiC are used in the calculation it is not possible to predict any particle failures, by which is meant when all three load bearing layers have failed. By contrast, when statistical variations in the fracture stresses and particle specifications are taken into account, as is done in the STAPLE code, failures can be predicted. In the HRB-22 irradiation test, it was concluded that the first two particles which had failed were defective in some way, but that the third and fourth failures can be accounted for by the pressure vessel model. In the 91F-1A irradiation test, the result showed that 1 or 2 particles had failed towards the end of irradiation in the upper capsule and no particles failed in the lower capsule. (author)

  4. Microcomputer based instrument for measuring a novel pulmonary function test

    Science.gov (United States)

    Craine, Brian L.; Craine, Eric R.

    1996-08-01

    The design of a prototype instrument for measuring the end-tidal concentration of carbon monoxide during human respiration is presented. The instrument automatically samples the final sixty cubic centimeters of exhaled breath, from successive breathing cycles, by coordinating a pump and the breathing cycle with a set of vacuum and pressure sensors. The concentration of carbon monoxide is measured using a nondispersive infrared spectrophotometer. The amount of carbon monoxide present is measured relative to the source air concentration eliminating the need for calibrating the instrument. The testing protocol and measurements can be controlled by a microcomputer connected to the instrument through a standard RS-232 serial interface. When at equilibrium, the end-tidal concentration of CO can be measured in a simple and reproducible fashion. This simplified technology allows for the construction of a small, portable, easy to use instrument that will allow the application of this new pulmonary function test at the point of contact with patients.

  5. VIRUS instrument enclosures

    Science.gov (United States)

    Prochaska, T.; Allen, R.; Mondrik, N.; Rheault, J. P.; Sauseda, M.; Boster, E.; James, M.; Rodriguez-Patino, M.; Torres, G.; Ham, J.; Cook, E.; Baker, D.; DePoy, Darren L.; Marshall, Jennifer L.; Hill, G. J.; Perry, D.; Savage, R. D.; Good, J. M.; Vattiat, Brian L.

    2014-08-01

    The Visible Integral-Field Replicable Unit Spectrograph (VIRUS) instrument will be installed at the Hobby-Eberly Telescope† in the near future. The instrument will be housed in two enclosures that are mounted adjacent to the telescope, via the VIRUS Support Structure (VSS). We have designed the enclosures to support and protect the instrument, to enable servicing of the instrument, and to cool the instrument appropriately while not adversely affecting the dome environment. The system uses simple HVAC air handling techniques in conjunction with thermoelectric and standard glycol heat exchangers to provide efficient heat removal. The enclosures also provide power and data transfer to and from each VIRUS unit, liquid nitrogen cooling to the detectors, and environmental monitoring of the instrument and dome environments. In this paper, we describe the design and fabrication of the VIRUS enclosures and their subsystems.

  6. Gemini Instrument Upgrade Program

    Science.gov (United States)

    Diaz, Ruben; Goodsell, Stephen; Kleinman, Scot

    2016-08-01

    The Gemini Observatory* remains committed to keeping its operational instrumentation competitive and serving the needs of its user community. Currently the observatory operates a 4 instruments + 1 AO system at each site. At Gemini North the GMOS-N, GNIRS, NIFS and NIRI instruments are offered supported by the ALTAIR AO system. In the south, GMOS-S, F-2, GPI and GSAOI are offered instrumentation and GeMS is the provided AO System. This paper reviews our strategy to keep our instrumentation suite competitive, examines both our current funded upgrade projects and our potential future enhancements. We summarize the work done and the results so far obtained within the instrument upgrade program.

  7. Instrumentation a reader

    CERN Document Server

    Pope, P

    1990-01-01

    This book contains a selection of papers and articles in instrumentation previously pub­ lished in technical periodicals and journals of learned societies. Our selection has been made to illustrate aspects of current practice and applications of instrumentation. The book does not attempt to be encyclopaedic in its coverage of the subject, but to provide some examples of general transduction techniques, of the sensing of particular measurands, of components of instrumentation systems and of instrumentation practice in two very different environments, the food industry and the nuclear power industry. We have made the selection particularly to provide papers appropriate to the study of the Open University course T292 Instrumentation. The papers have been chosen so that the book covers a wide spectrum of instrumentation techniques. Because of this, the book should be of value not only to students of instrumen­ tation, but also to practising engineers and scientists wishing to glean ideas from areas of instrumen...

  8. Aircrew Screening Instruments Review

    Science.gov (United States)

    2007-09-01

    available tools . Several vendors indicated that they will have new selection instruments available within a few months. These are not listed. As noted...AFCAPS-FR-2011-0012 AIRCREW SCREENING INSTRUMENTS REVIEW Diane L. Damos Damos Aviation Services, Inc...June 2007 – August 2007 4. TITLE AND SUBTITLE Aircrew Screening Instruments Review 5a. CONTRACT NUMBER FA3089-06-F-0385 5b. GRANT NUMBER 5c

  9. Design of automatic leveling and centering system of theodolite

    Science.gov (United States)

    Liu, Chun-tong; He, Zhen-Xin; Huang, Xian-xiang; Zhan, Ying

    2012-09-01

    To realize the theodolite automation and improve the azimuth Angle measurement instrument, the theodolite automatic leveling and centering system with the function of leveling error compensation is designed, which includes the system solution, key components selection, the mechanical structure of leveling and centering, and system software solution. The redesigned leveling feet are driven by the DC servo motor; and the electronic control center device is installed. Using high precision of tilt sensors as horizontal skew detection sensors ensures the effectiveness of the leveling error compensation. Aiming round mark center is located using digital image processing through surface array CCD; and leveling measurement precision can reach the pixel level, which makes the theodolite accurate centering possible. Finally, experiments are conducted using the automatic leveling and centering system of the theodolite. The results show the leveling and centering system can realize automatic operation with high centering accuracy of 0.04mm.The measurement precision of the orientation angle after leveling error compensation is improved, compared with that of in the traditional method. Automatic leveling and centering system of theodolite can satisfy the requirements of the measuring precision and its automation.

  10. Ocean Optics Instrumentation Systems

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation suites for a wide variety of measurements to characterize the ocean’s optical environment. These packages have been developed to...

  11. [Controlling instruments in radiology].

    Science.gov (United States)

    Maurer, M

    2013-10-01

    Due to the rising costs and competitive pressures radiological clinics and practices are now facing, controlling instruments are gaining importance in the optimization of structures and processes of the various diagnostic examinations and interventional procedures. It will be shown how the use of selected controlling instruments can secure and improve the performance of radiological facilities. A definition of the concept of controlling will be provided. It will be shown which controlling instruments can be applied in radiological departments and practices. As an example, two of the controlling instruments, material cost analysis and benchmarking, will be illustrated.

  12. Networked Instrumentation Element

    Data.gov (United States)

    National Aeronautics and Space Administration — Armstrong researchers have developed a networked instrumentation system that connects modern experimental payloads to existing analog and digital communications...

  13. Thoughts on Building Non-staple Grain Industrialization System%关于构建杂粮产业化体系的若干思考

    Institute of Scientific and Technical Information of China (English)

    牟少岩; 李敬锁

    2014-01-01

    Our country is the largest non-staple grain producer , but the level of industrial development is still comparatively low .In view of the difficulties of large-scale planting in the industrial development of non-staple grain,high market transaction costs and incomplete industrial chain , the non-staple grain industrialization system with the appropriate planting concentration ,relying on industrial organizations and executing brand strategies should be built to promote the development of grain industry , serve better the needs of the new national food security strategy ,improve the international competitiveness of agriculture and ensure that the non-staple grain can play a role in health care .%我国是杂粮生产大国,但杂粮的产业化发展水平还较低。针对当前影响杂粮产业化发展的规模化种植难度大、市场交易成本高和产业链条不完整等障碍,应着力构建以种植适当集中、依托产业组织和实施品牌战略为主要内容的杂粮产业化体系,以促进杂粮产业发展更好的服务于国家粮食安全新战略的需要、带动农业国际竞争力的提升和发挥杂粮的保健作用。

  14. 短纤纺技术用于处理碳纤维的可能性%Potentials of carbon fiber processing in staple fiber spinning

    Institute of Scientific and Technical Information of China (English)

    J. Hehl; S. Baz; U. Heitmann; G. T. Gresser; 仰林(译); 颜雪(校)

    2015-01-01

    Staple fiber technology offers a multitude of opportunities to process stretch broken or recycled carbon fibers. Especially the high flexibility in the production with regards to the yarn fineness and the yarn construction in combination with the possible lower costs for the raw materials emphasize the potential of the staple fiber technology in the large batch production of CFRP. The material parameters can be optimized to the application. New processes in staple fiber spinning, such as the tape production can bring forth more advantages beyond conventional methods, e. g. through a process shortening in spinning or an increase of productivity in further processing. Besides the economic advantages of staple fiber products, many opportunities for the optimization of the material properties in view of the fields of application arise.%短纤维技术为处理拉伸断裂的或再利用的碳纤维提供了多种可能,尤其是与可能的低成本原料混合生产时,在纱线细度和纱线结构方面能体现出高度灵活性,着重体现了短纤维技术在碳纤维复合材料大批量生产中的潜能。材料参数可根据应用优化。新的短纤加工技术(如扁丝生产)比传统技术具有更多优势,如通过一项处理可缩短纺纱时间,或在后续加工中提高生产效率。除短纤维产品的经济优势外,应用领域中许多优化材料性能的机会也逐渐显现。

  15. Annual review in automatic programming

    CERN Document Server

    Goodman, Richard

    2014-01-01

    Annual Review in Automatic Programming focuses on the techniques of automatic programming used with digital computers. Topics covered range from the design of machine-independent programming languages to the use of recursive procedures in ALGOL 60. A multi-pass translation scheme for ALGOL 60 is described, along with some commercial source languages. The structure and use of the syntax-directed compiler is also considered.Comprised of 12 chapters, this volume begins with a discussion on the basic ideas involved in the description of a computing process as a program for a computer, expressed in

  16. Algorithms for skiascopy measurement automatization

    Science.gov (United States)

    Fomins, Sergejs; Trukša, Renārs; KrūmiĆa, Gunta

    2014-10-01

    Automatic dynamic infrared retinoscope was developed, which allows to run procedure at a much higher rate. Our system uses a USB image sensor with up to 180 Hz refresh rate equipped with a long focus objective and 850 nm infrared light emitting diode as light source. Two servo motors driven by microprocessor control the rotation of semitransparent mirror and motion of retinoscope chassis. Image of eye pupil reflex is captured via software and analyzed along the horizontal plane. Algorithm for automatic accommodative state analysis is developed based on the intensity changes of the fundus reflex.

  17. Automatic Construction of Finite Algebras

    Institute of Scientific and Technical Information of China (English)

    张健

    1995-01-01

    This paper deals with model generation for equational theories,i.e.,automatically generating (finite)models of a given set of (logical) equations.Our method of finite model generation and a tool for automatic construction of finite algebras is described.Some examples are given to show the applications of our program.We argue that,the combination of model generators and theorem provers enables us to get a better understanding of logical theories.A brief comparison betwween our tool and other similar tools is also presented.

  18. Automatic mapping of monitoring data

    DEFF Research Database (Denmark)

    Lophaven, Søren; Nielsen, Hans Bruun; Søndergaard, Jacob

    2005-01-01

    This paper presents an approach, based on universal kriging, for automatic mapping of monitoring data. The performance of the mapping approach is tested on two data-sets containing daily mean gamma dose rates in Germany reported by means of the national automatic monitoring network (IMIS......). In the second dataset an accidental release of radioactivity in the environment was simulated in the South-Western corner of the monitored area. The approach has a tendency to smooth the actual data values, and therefore it underestimates extreme values, as seen in the second dataset. However, it is capable...

  19. The Integration of Technology and Management in the Competitiveness of the United States Short Staple Yarn Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    Suvalee T. Tangboonritruthai

    2014-01-01

    Full Text Available The purpose of this research was to investigate whether a balance of technology and management could be used in order to sustain a viable United States (US short staple yarn production industry. The methodology used in this study consisted of primary research comprising two phases. The first phase consisted of interviews with industry executives in order to find out what US yarn manufacturers think are the important factors in maintaining a competitive yarn industry. The second phase was an online survey with industry customers in order to find out why weavers and knitters buy from US manufacturers. Results reveal that US manufacturers have competitive advantages over other countries because of skill level of workforce, variety of products offered, customer relationships, innovation and technology, and product quality. In order to keep these competitive advantages, “technology” and “management” strategies should be implemented. Results also reveal the areas in which the US yarn manufacturers should focus their resources in order to stay competitive or indeed survive.

  20. Factors Predicting Difficulty of Laparoscopic Low Anterior Resection for Rectal Cancer with Total Mesorectal Excision and Double Stapling Technique.

    Directory of Open Access Journals (Sweden)

    Weiping Chen

    Full Text Available Laparoscopic sphincter-preserving low anterior resection for rectal cancer is a surgery demanding great skill. Immense efforts have been devoted to identifying factors that can predict operative difficulty, but the results are inconsistent.Our study was conducted to screen patients' factors to build models for predicting the operative difficulty using well controlled data.We retrospectively reviewed records of 199 consecutive patients who had rectal cancers 5-8 cm from the anal verge. All underwent laparoscopic sphincter-preserving low anterior resections with total mesorectal excision (TME and double stapling technique (DST. Data of 155 patients from one surgeon were utilized to build models to predict standardized endpoints (operative time, blood loss and postoperative morbidity. Data of 44 patients from other surgeons were used to test the predictability of the built models.Our results showed prior abdominal surgery, preoperative chemoradiotherapy, tumor distance to anal verge, interspinous distance, and BMI were predictors for the standardized operative times. Gender and tumor maximum diameter were related to the standardized blood loss. Temporary diversion and tumor diameter were predictors for postoperative morbidity. The model constructed for the operative time demonstrated excellent predictability for patients from different surgeons.With a well-controlled patient population, we have built a predictable model to estimate operative difficulty. The standardized operative time will make it possible to significantly increase sample size and build more reliable models to predict operative difficulty for clinical use.

  1. A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.

    Science.gov (United States)

    Chen, Xishan; Tai, Lingyu; Gao, Jie; Qian, Jianchang; Zhang, Mingfei; Li, Beibei; Xie, Cao; Lu, Linwei; Lu, Wuyuan; Lu, Weiyue

    2015-11-28

    Antagonizing MDM2 and MDMX to activate the tumor suppressor protein p53 is an attractive therapeutic paradigm for the treatment of glioblastoma multiforme (GBM). However, challenges remain with respect to the poor ability of p53 activators to efficiently cross the blood-brain barrier and/or blood-brain tumor barrier and to specifically target tumor cells. To circumvent these problems, we developed a cyclic RGD peptide-conjugated poly(ethylene glycol)-co-poly(lactic acid) polymeric micelle (RGD-M) that carried a stapled peptide antagonist of both MDM2 and MDMX (sPMI). The peptide-carrying micelle RGD-M/sPMI was prepared via film-hydration method with high encapsulation efficiency and loading capacity as well as ideal size distribution. Micelle encapsulation dramatically increased the solubility of sPMI, thus alleviating its serum sequestration. In vitro studies showed that RGD-M/sPMI efficiently inhibited the proliferation of glioma cells in the presence of serum by activating the p53 signaling pathway. Further, RGD-M/sPMI exerted potent tumor growth inhibitory activity against human glioblastoma in nude mouse xenograft models. Importantly, the combination of RGD-M/sPMI and temozolomide--a standard chemotherapy drug for GBM increased antitumor efficacy against glioblastoma in experimental animals. Our results validate a combination therapy using p53 activators with temozolomide as a more effective treatment for GBM.

  2. Instrumentation and Controls Division annual progress report for period ending September 1, 1973

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)

    1976-08-01

    Research progress is described under the following topics: (1) pulse counting and analysis; (2) support for the thermonuclear division ORMAK project; (3) miscellaneous electronics development; (4) detectors of ionizing particles and radiation; (5) radiation monitoring; (6) support for the Oak Ridge Electron Linear Accelerator; (7) automatic control and data acquisition; (8) process instrumentation and control; (9) reactor instrumentation and controls; (10) instrumentation for reactor division experiments and test loops; (11) maintenance and service; and (12) ecological science studies. (WHK)

  3. MC and A instrumentation catalog

    Energy Technology Data Exchange (ETDEWEB)

    Neymotin, L. [ed.] [Brookhaven National Lab., Upton, NY (United States); Sviridova, V. [ed.] [All-Russian Research Inst. of Automatics, Moscow (Russian Federation)

    1998-06-01

    In 1981 and 1985, two editions of a catalog of non-destructive nuclear measurement instrumentation, and material control and surveillance equipment, were published by Brookhaven National Laboratory (BNL). The last edition of the catalog included one hundred and twenty-five entries covering a wide range of devices developed in the US and abroad. More than ten years have elapsed since the publication of the more recent Catalog. Devices described in it have undergone significant modifications, and new devices have been developed. Therefore, in order to assist specialists in the field of Material Control and Accounting (MC and A), a new catalog has been created. Work on this instrumentation catalog started in 1997 as a cooperative effort of Brookhaven National Laboratory (BNL), operated by Brookhaven Science Associates under contract to the US Department of Energy, and the All-Russian Research Institute of Automatics (VNIIA), subordinate institute of the Atomic Energy Ministry of the Russian Federation, within the collaborative US-Russia Material Protection, Control, and Accounting (MPC and A) Program. Most of the equipment included in the Catalog are non-destructive assay (NDA) measurement devices employed for purposes of accounting, confirmation, and verification of nuclear materials. Other devices also included in the Catalog are employed in the detection and deterrence of unauthorized access to or removal of nuclear materials (material control: containment and surveillance). Equipment found in the Catalog comprises either: (1) complete devices or systems that can be used for MC and A applications; or (2) parts or components of complete systems, such as multi-channel analyzers, detectors, neutron generators, and software. All devices are categorized by their status of development--from prototype to serial production.

  4. Instrumentation Design and Development Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — RTTC has facilities for design, development and fabrication of: custominstrumentation, mobile instrumentation, miniaturized instrumentation, wirelessinstrumentation,...

  5. Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.

    Science.gov (United States)

    Chang, Yong S; Graves, Bradford; Guerlavais, Vincent; Tovar, Christian; Packman, Kathryn; To, Kwong-Him; Olson, Karen A; Kesavan, Kamala; Gangurde, Pranoti; Mukherjee, Aditi; Baker, Theresa; Darlak, Krzysztof; Elkin, Carl; Filipovic, Zoran; Qureshi, Farooq Z; Cai, Hongliang; Berry, Pamela; Feyfant, Eric; Shi, Xiangguo E; Horstick, James; Annis, D Allen; Manning, Anthony M; Fotouhi, Nader; Nash, Huw; Vassilev, Lyubomir T; Sawyer, Tomi K

    2013-09-03

    Stapled α-helical peptides have emerged as a promising new modality for a wide range of therapeutic targets. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX, ATSP-7041, which effectively activates the p53 pathway in tumors in vitro and in vivo. Specifically, ATSP-7041 binds both MDM2 and MDMX with nanomolar affinities, shows submicromolar cellular activities in cancer cell lines in the presence of serum, and demonstrates highly specific, on-target mechanism of action. A high resolution (1.7-Å) X-ray crystal structure reveals its molecular interactions with the target protein MDMX, including multiple contacts with key amino acids as well as a role for the hydrocarbon staple itself in target engagement. Most importantly, ATSP-7041 demonstrates robust p53-dependent tumor growth suppression in MDM2/MDMX-overexpressing xenograft cancer models, with a high correlation to on-target pharmacodynamic activity, and possesses favorable pharmacokinetic and tissue distribution properties. Overall, ATSP-7041 demonstrates in vitro and in vivo proof-of-concept that stapled peptides can be developed as therapeutically relevant inhibitors of protein-protein interaction and may offer a viable modality for cancer therapy.

  6. When the End (Automatically) Justifies the Means: Automatic Tendency Toward Sex Exchange for Crack Cocaine

    Science.gov (United States)

    Kopetz, Catalina E.; Collado, Anahi; Lejuez, Carl W.

    2016-01-01

    The current research explores the idea that self-defeating behaviors represent means toward individuals’ goals. In this quality, they may be automatically initiated upon goal activation without individual’s voluntary intention and thus exemplify the long-held idea that the end justifies the means. To investigate this notion empirically we explored one of the most problematic self-defeating behavior: engagement in sex exchange for crack cocaine. This behavior is common among female drug users despite its well-known health and legal consequences. Although these women know and understand the consequences of such behavior, they have a hard time resisting it when the goal of drug obtainment becomes accessible. Indeed, the current study shows that when the accessibility of such a goal is experimentally increased, participants for whom sex exchange represents an instrumental means to drug obtainment are faster to approach sex-exchange targets in a joystick task despite their self-reported intentions to avoid such behavior.

  7. 2011 International Conference in Electrics, Communication and Automatic Control Proceedings

    CERN Document Server

    2012-01-01

    This two-volume set contains the very latest, cutting-edge material in electrics, communication and automatic control. As a vital field of research that is highly relevant to current developments in a number of technological domains, the subjects it covers include micro-electronics and integrated circuit control, signal processing technology, next-generation network infrastructure, wireless communication and scientific instruments. The aim of the International Conference in Electrics, Communication and Automatic Control, held in Chongqing, China, in June 2011 was to provide a valuable inclusive platform for researchers, engineers, academicians and industrial professionals from all over the world to share their research results with fellow scientists in the sector. The call for papers netted well over 600 submissions, of which 224 were selected for presentation. This fully peer-reviewed collection of papers from the conference can be viewed as a single-source compendium of the latest trends and techniques in t...

  8. 5th International Conference on Electrical Engineering and Automatic Control

    CERN Document Server

    Yao, Yufeng

    2016-01-01

    On the basis of instrument electrical and automatic control system, the 5th International Conference on Electrical Engineering and Automatic Control (CEEAC) was established at the crossroads of information technology and control technology, and seeks to effectively apply information technology to a sweeping trend that views control as the core of intelligent manufacturing and life. This book takes a look forward into advanced manufacturing development, an area shaped by intelligent manufacturing. It highlights the application and promotion of process control represented by traditional industries, such as the steel industry and petrochemical industry; the technical equipment and system cooperative control represented by robot technology and multi-axis CNC; and the control and support of emerging process technologies represented by laser melting and stacking, as well as the emerging industry represented by sustainable and intelligent life. The book places particular emphasis on the micro-segments field, such as...

  9. Instrumentation and Controls Division annual progress report for period ending September 1, 1974. Non-LMFBR program

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)

    1976-09-01

    Research projects are summarized under the following categories: (1) basic electronics development; (2) engineering support for research facilities; (3) pulse counting and analysis; (4) radiation detection and monitoring; (5) instrument development; (6) automatic control and data acquisition; (7) process systems and instrumentation development; (8) reactor instrumentation and controls; (9) fuel reprocessing and shipping; (10) standards laboratory; (11) instrumentation for reactor division experiments and test loops; (12) maintenance and service; (13) ecological science studies; and (14) administration and training. (WHK)

  10. Instrumentation in endourology

    OpenAIRE

    Khanna, Rakesh; Monga,Manoj

    2011-01-01

    Success with endourological procedures requires expertise and instrumentation. This review focuses on the instrumentation required for ureteroscopy and percutaneous nephrolithotomy, and provides a critical assessment of in vitro and clinical studies that have evaluated the comparative effectiveness of these medical devices.

  11. BAA instrument no. 93

    Science.gov (United States)

    Marriott, R. A.

    2006-12-01

    Instrument no. 93 has been in almost continual use for more than a hundred years. Since it left the workshop of its maker, George Calver, it has kept company with several other notable instruments and has been used by many eminent astronomers. It was added to the Association's collection in 1945.

  12. Development of autonomous triggering instrumentation

    Science.gov (United States)

    Watkins, Steve E.; Swift, Theresa M.; Fonda, James W.

    2008-03-01

    Triggering instrumentation for autonomous monitoring of load-induced strain is described for economical, fast bridge inspection. The development addresses one aspect for the management of transportation infrastructure - bridge monitoring and inspection. The objectives are to provide quantitative performance information from a load test, to minimize the setup time at the bridge, and to minimize the closure time to traffic. Multiple or networked measurements can be made for a prescribed loading sequence. The proposed smart system consists of in-situ strain sensors, an embedded data acquisition module, and a measurement triggering system. A companion control unit is mounted on the truck serving as the load. As the truck moves to the proper position, the desired measurement is automatically relayed back to the control unit. In this work, the testing protocol is developed and the performance parameters for the triggering and data acquisition are measured. The test system uses a dedicated wireless sensor mote and an infrared positioning system. The electronic procedure offers improvements in available information and economics.

  13. Automatic quantification of iris color

    DEFF Research Database (Denmark)

    Christoffersen, S.; Harder, Stine; Andersen, J. D.;

    2012-01-01

    An automatic algorithm to quantify the eye colour and structural information from standard hi-resolution photos of the human iris has been developed. Initially, the major structures in the eye region are identified including the pupil, iris, sclera, and eyelashes. Based on this segmentation, the ...

  14. Trevi Park: Automatic Parking System

    OpenAIRE

    ECT Team, Purdue

    2007-01-01

    TreviPark is an underground, multi-story stacking system that holds cars efficiently, thus reducing the cost of each parking space, as a fully automatic parking system intended to maximize space utilization in parking structures. TreviPark costs less than the price of a conventional urban garage and takes up half the volume and 80% of the depth.

  15. Automatic agar tray inoculation device

    Science.gov (United States)

    Wilkins, J. R.; Mills, S. M.

    1972-01-01

    Automatic agar tray inoculation device is simple in design and foolproof in operation. It employs either conventional inoculating loop or cotton swab for uniform inoculation of agar media, and it allows technician to carry on with other activities while tray is being inoculated.

  16. Automatic Error Analysis Using Intervals

    Science.gov (United States)

    Rothwell, E. J.; Cloud, M. J.

    2012-01-01

    A technique for automatic error analysis using interval mathematics is introduced. A comparison to standard error propagation methods shows that in cases involving complicated formulas, the interval approach gives comparable error estimates with much less effort. Several examples are considered, and numerical errors are computed using the INTLAB…

  17. Automatic Validation of Protocol Narration

    DEFF Research Database (Denmark)

    Bodei, Chiara; Buchholtz, Mikael; Degano, Pierpablo;

    2003-01-01

    We perform a systematic expansion of protocol narrations into terms of a process algebra in order to make precise some of the detailed checks that need to be made in a protocol. We then apply static analysis technology to develop an automatic validation procedure for protocols. Finally, we...

  18. Automatic Identification of Metaphoric Utterances

    Science.gov (United States)

    Dunn, Jonathan Edwin

    2013-01-01

    This dissertation analyzes the problem of metaphor identification in linguistic and computational semantics, considering both manual and automatic approaches. It describes a manual approach to metaphor identification, the Metaphoricity Measurement Procedure (MMP), and compares this approach with other manual approaches. The dissertation then…

  19. Automatic milking : a better understanding

    NARCIS (Netherlands)

    Meijering, A.; Hogeveen, H.; Koning, de C.J.A.M.

    2004-01-01

    In 2000 the book Robotic Milking, reflecting the proceedings of an International Symposium which was held in The Netherlands came out. At that time, commercial introduction of automatic milking systems was no longer obstructed by technological inadequacies. Particularly in a few west-European countr

  20. Automatic system for the determination of metals by anodic stripping potentiometry in non-deaerated samples

    OpenAIRE

    1990-01-01

    An automatic system for the determination of Zn, Cd, Pb and Cu by anodic stripping potentiometry using the oxygen dissolved in the sample as oxidant is reported. The system relies on the use of a PC-compatible computer for instrumental control and data acquisition and processing.

  1. The two-probe device for automatic measurement of the reflection coefficient

    Directory of Open Access Journals (Sweden)

    Л.Я. Ільницький

    2004-01-01

    Full Text Available  The two-probe device for automatic measurement of the reflection coefficient in the HF range is proposed and analyzed. The main parts in the instrument control system are the sum-and-difference bridge and the microprocessor.

  2. Implementation of a microcontroller-based semi-automatic coagulator.

    Science.gov (United States)

    Chan, K; Kirumira, A; Elkateeb, A

    2001-01-01

    The coagulator is an instrument used in hospitals to detect clot formation as a function of time. Generally, these coagulators are very expensive and therefore not affordable by a doctors' office and small clinics. The objective of this project is to design and implement a low cost semi-automatic coagulator (SAC) prototype. The SAC is capable of assaying up to 12 samples and can perform the following tests: prothrombin time (PT), activated partial thromboplastin time (APTT), and PT/APTT combination. The prototype has been tested successfully.

  3. Biomedical Sensors and Instruments

    CERN Document Server

    Tagawa, Tatsuo

    2011-01-01

    The living body is a difficult object to measure: accurate measurements of physiological signals require sensors and instruments capable of high specificity and selectivity that do not interfere with the systems under study. As a result, detailed knowledge of sensor and instrument properties is required to be able to select the "best" sensor from one of the many designed to meet these challenges. From the underlying principles to practical applications, this updated edition of Biomedical Sensors and Instruments provides an easy-to-understand introduction to the various kinds of biome

  4. Medical instruments in museums

    DEFF Research Database (Denmark)

    Söderqvist, Thomas; Arnold, Ken

    2011-01-01

    This essay proposes that our understanding of medical instruments might benefit from adding a more forthright concern with their immediate presence to the current historical focus on simply decoding their meanings and context. This approach is applied to the intriguingly tricky question of what...... actually is meant by a "medical instrument." It is suggested that a pragmatic part of the answer might lie simply in reconsidering the holdings of medical museums, where the significance of the physical actuality of instruments comes readily to hand....

  5. Instrumentation reference book

    CERN Document Server

    Boyes, Walt

    2002-01-01

    Instrumentation is not a clearly defined subject, having a 'fuzzy' boundary with a number of other disciplines. Often categorized as either 'techniques' or 'applications' this book addresses the various applications that may be needed with reference to the practical techniques that are available for the instrumentation or measurement of a specific physical quantity or quality. This makes it of direct interest to anyone working in the process, control and instrumentation fields where these measurements are essential.* Comprehensive and authoritative collection of technical information* Writte

  6. Manual of Surgical Instruments

    Directory of Open Access Journals (Sweden)

    Olga Lidia Sánchez Sarría

    2014-10-01

    Full Text Available Surgical instruments are the group of tools used in surgical procedures. They are very expensive and sophisticated. Consequently, a standardized and meticulous care is essential; they should go through the decontamination, cleaning and sterilization process. These instruments are designed in order to provide surgeons with tools that help them to perform a basic surgical procedure; there are multiple variations and the design depends on their function. This paper aims at showing all surgical instruments that can be used in an operating room during surgery and are not generally included in the medical literature.

  7. Mass spectrometers: instrumentation

    Science.gov (United States)

    Cooks, R. G.; Hoke, S. H., II; Morand, K. L.; Lammert, S. A.

    1992-09-01

    Developments in mass spectrometry instrumentation over the past three years are reviewed. The subject is characterized by an enormous diversity of designs, a high degree of competition between different laboratories working with either different or similar techniques and by extremely rapid progress in improving analytical performance. Instruments can be grouped into genealogical charts based on their physical and conceptual interrelationships. This is illustrated using mass analyzers of different types. The time course of development of particular instrumental concepts is illustrated in terms of the s-curves typical of cell growth. Examples are given of instruments which are at the exponential, linear and mature growth stages. The prime examples used are respectively: (i) hybrid instruments designed to study reactive collisions of ions with surfaces: (ii) the Paul ion trap; and (iii) the triple quadrupole mass spectrometer. In the area of ion/surface collisions, reactive collisions such as hydrogen radical abstraction from the surface by the impinging ion are studied. They are shown to depend upon the chemical nature of the surface through the use of experiments which utilize self-assembled monolayers as surfaces. The internal energy deposited during surface-induced dissociation upon collision with different surfaces in a BEEQ instrument is also discussed. Attention is also given to a second area of emerging instrumentation, namely technology which allows mass spectrometers to be used for on-line monitoring of fluid streams. A summary of recent improvements in the performance of the rapidly developing quadrupole ion trap instrument illustrates this stage of instrument development. Improvements in resolution and mass range and their application to the characterization of biomolecules are described. The interaction of theory with experiment is illustrated through the role of simulations of ion motion in the ion trap. It is emphasized that mature instruments play a

  8. An Automatic Proof of Euler's Formula

    Directory of Open Access Journals (Sweden)

    Jun Zhang

    2005-05-01

    Full Text Available In this information age, everything is digitalized. The encoding of functions and the automatic proof of functions are important. This paper will discuss the automatic calculation for Taylor expansion coefficients, as an example, it can be applied to prove Euler's formula automatically.

  9. Self-Compassion and Automatic Thoughts

    Science.gov (United States)

    Akin, Ahmet

    2012-01-01

    The aim of this research is to examine the relationships between self-compassion and automatic thoughts. Participants were 299 university students. In this study, the Self-compassion Scale and the Automatic Thoughts Questionnaire were used. The relationships between self-compassion and automatic thoughts were examined using correlation analysis…

  10. Automatic Control System for Neutron Laboratory Safety

    Institute of Scientific and Technical Information of China (English)

    ZHAO; Xiao; ZHANG; Guo-guang; FENG; Shu-qiang; SU; Dan; YANG; Guo-zhao; ZHANG; Shuai

    2015-01-01

    In order to cooperate with the experiment of neutron generator,and realize the automatic control in the experiment,a set of automatic control system for the safety of the neutron laboratory is designed.The system block diagram is shown as Fig.1.Automatic control device is for processing switch signal,so PLC is selected as the core component

  11. Comparative outcome of stapled trans-anal rectal resection and macrogol in the treatment of defecation disorders

    Institute of Scientific and Technical Information of China (English)

    Ivano Biviano; Danilo Badiali; Laura Candeloro; Fortunee Irene Habib; Massimo Mongardini; Angelo Caviglia; Fiorella Anzini; Enrico S Corazziari

    2011-01-01

    AIM: To prospectively assess the efficacy and safety of stapled trans-anal rectal resection (STARR) compared to standard conservative treatment, and whether preoperative symptoms and findings at defecography and anorectal manometry can predict the outcome of STARR. METHODS: Thirty patients (Female, 28; age: 51 ± 9 years) with rectocele or rectal intussusception, a defecation disorder, and functional constipation were submitted for STARR. Thirty comparable patients (Female, 30; age 53 ± 13 years), who presented with symptoms of rectocele or rectal intussusception and were treated with macrogol, were assessed. Patients were interviewed with a standardized questionnaire at study enrollment and 38 ± 18 mo after the STARR procedure or during macrogol treatment. A responder was defined as an absence of the Rome El diagnostic criteria for functional constipation. Defecography and recto-anal manometry were performed before and after the STARR procedure in 16 and 12 patients, respectively. RESULTS: After STARR, 53% of patients were re-sponders; during conservative treatment, 75% were responders. After STARR, 30% of the patients reported the use of laxatives, 17% had intermittent anal pain, 13% had anal leakage, 13% required digital facilitation, 6% experienced defecatory urgency, 6% experienced fecal incontinence, and 6% required re-intervention. During macrogol therapy, 23% of the patients complained of abdominal bloating and 13% of borborygmi, and 3% required digital facilitation.No preoperative symptom, defecographic, or manometric finding predicted the outcome of STARR. Post-operative defecography showed a statistically significant reduction (P < 0.05) of the rectal diameter and rectocele. The postoperative anorectal manometry showed that anal pressure and rectal sensitivity were not significantly modified, and that rectal compliance was reduced (P = 0.01). CONCLUSION: STARR is not better and is less safe than macrogol in the treatment of defecation disorders. It

  12. Study of instrumentation needs for process control and safety in coal fluidized-bed combustion systems

    Energy Technology Data Exchange (ETDEWEB)

    Herzenberg, C.L.; Griggs, K.E.; Henry, R.F.; Podolski, W.F.

    1981-02-01

    A study was conducted to evaluate the current state of the art of instrumentation for planned and operating fluidized-bed combustion systems. This study is intended to identify instrumentation needs and serve as a data base for projects to develop this instrumentation. A considerable number of needs for measurements for which presently available instrumentation is not suitable were reported by respondents. The identified deficiencies are presented with the associated physical parameter ranges for FBC processes. New techniques and instrumentation under development, as well as some available alternative instruments, are discussed briefly. Also, newly instituted mechanisms for technical information exchange on instrumentation for fossil energy applications are identified. Development of instruments to meet the identified measurement deficiencies is recommended in order to ensure the feasibility of automatic control of large-scale fluidized-bed combustion systems, and to advance the state of the art of fluidized-bed combustion technology.

  13. UV and EUV Instruments

    CERN Document Server

    Werner, K

    2010-01-01

    We describe telescopes and instruments that were developed and used for astronomical research in the ultraviolet (UV) and extreme ultraviolet (EUV) regions of the electromagnetic spectrum. The wavelength ranges covered by these bands are not uniquely defined. We use the following convention here: The EUV and UV span the regions ~100-912 and 912-3000 Angstroem respectively. The limitation between both ranges is a natural choice, because the hydrogen Lyman absorption edge is located at 912 Angstroem. At smaller wavelengths, astronomical sources are strongly absorbed by the interstellar medium. It also marks a technical limit, because telescopes and instruments are of different design. In the EUV range, the technology is strongly related to that utilized in X-ray astronomy, while in the UV range the instruments in many cases have their roots in optical astronomy. We will, therefore, describe the UV and EUV instruments in appropriate conciseness and refer to the respective chapters of this volume for more technic...

  14. Fiber Optics Instrumentation Development

    Science.gov (United States)

    Chan, Patrick Hon Man; Parker, Allen R., Jr.; Richards, W. Lance

    2010-01-01

    This is a general presentation of fiber optics instrumentation development work being conducted at NASA Dryden for the past 10 years and recent achievements in the field of fiber optics strain sensors.

  15. PLC Based Automatic Multistoried Car Parking System

    Directory of Open Access Journals (Sweden)

    Swanand S .Vaze

    2014-12-01

    Full Text Available This project work presents the study and design of PLC based Automatic Multistoried Car Parking System. Multistoried car parking is an arrangement which is used to park a large number of vehicles in least possible place. For making this arrangement in a real plan very high technological instruments are required. In this project a prototype of such a model is made. This prototype model is made for accommodating twelve cars at a time. Availability of the space for parking is detected by optical proximity sensor which is placed on the pallet. A motor controlled elevator is used to lift the cars. Elevator status is indicated by LED which is placed on ground floor. Controlling of the platforms and checking the vacancies is done by PLC. For unparking of car, keyboard is interfaced with the model for selection of required platform. Automation is done to reduce requirement of space and also to reduce human errors, which in-turn results in highest security and greatest flexibility. Due to these advantages, this system can be used in hotels, railway stations, airports where crowding of car is more.

  16. Automatic Waterline Extraction from Smartphone Images

    Science.gov (United States)

    Kröhnert, M.

    2016-06-01

    Considering worldwide increasing and devastating flood events, the issue of flood defence and prediction becomes more and more important. Conventional methods for the observation of water levels, for instance gauging stations, provide reliable information. However, they are rather cost-expensive in purchase, installation and maintenance and hence mostly limited for monitoring large streams only. Thus, small rivers with noticeable increasing flood hazard risks are often neglected. State-of-the-art smartphones with powerful camera systems may act as affordable, mobile measuring instruments. Reliable and effective image processing methods may allow the use of smartphone-taken images for mobile shoreline detection and thus for water level monitoring. The paper focuses on automatic methods for the determination of waterlines by spatio-temporal texture measures. Besides the considerable challenge of dealing with a wide range of smartphone cameras providing different hardware components, resolution, image quality and programming interfaces, there are several limits in mobile device processing power. For test purposes, an urban river in Dresden, Saxony was observed. The results show the potential of deriving the waterline with subpixel accuracy by a column-by-column four-parameter logistic regression and polynomial spline modelling. After a transformation into object space via suitable landmarks (which is not addressed in this paper), this corresponds to an accuracy in the order of a few centimetres when processing mobile device images taken from small rivers at typical distances.

  17. Modeling of Musical Instruments

    Science.gov (United States)

    Bader, Rolf; Hansen, Uwe

    Signal processing techniques in acoustics address many concerns. Included are such things as wave propagation variables, amplitude considerations, spectral content, wavelength, and phase. Phase is primarily of concern when waves interact with each other, as well as with a medium, and the imposition of boundary conditions leads to normal mode vibrations. Such conditions are prevalent in all musical instruments, and thus relevant signal processing techniques are essential to both understanding and modeling the structure of musical instruments and the sound radiated.

  18. Automatic Schema Evolution in Root

    Institute of Scientific and Technical Information of China (English)

    ReneBrun; FonsRademakers

    2001-01-01

    ROOT version 3(spring 2001) supports automatic class schema evolution.In addition this version also produces files that are self-describing.This is achieved by storing in each file a record with the description of all the persistent classes in the file.Being self-describing guarantees that a file can always be read later,its structure browsed and objects inspected.also when the library with the compiled code of these classes is missing The schema evolution mechanism supports the frequent case when multiple data sets generated with many different class versions must be analyzed in the same session.ROOT supports the automatic generation of C++ code describing the data objects in a file.

  19. Automatic spikes detection in seismogram

    Institute of Scientific and Technical Information of China (English)

    王海军; 靳平; 刘贵忠

    2003-01-01

    @@ Data processing for seismic network is very complex and fussy, because a lot of data is recorded in seismic network every day, which make it impossible to process these data all by manual work. Therefore, seismic data should be processed automatically to produce a initial results about events detection and location. Afterwards, these results are reviewed and modified by analyst. In automatic processing data quality checking is important. There are three main problem data thatexist in real seismic records, which include: spike, repeated data and dropouts. Spike is defined as isolated large amplitude point; the other two problem datahave the same features that amplitude of sample points are uniform in a interval. In data quality checking, the first step is to detect and statistic problem data in a data segment, if percent of problem data exceed a threshold, then the whole data segment is masked and not be processed in the later process.

  20. Physics of Automatic Target Recognition

    CERN Document Server

    Sadjadi, Firooz

    2007-01-01

    Physics of Automatic Target Recognition addresses the fundamental physical bases of sensing, and information extraction in the state-of-the art automatic target recognition field. It explores both passive and active multispectral sensing, polarimetric diversity, complex signature exploitation, sensor and processing adaptation, transformation of electromagnetic and acoustic waves in their interactions with targets, background clutter, transmission media, and sensing elements. The general inverse scattering, and advanced signal processing techniques and scientific evaluation methodologies being used in this multi disciplinary field will be part of this exposition. The issues of modeling of target signatures in various spectral modalities, LADAR, IR, SAR, high resolution radar, acoustic, seismic, visible, hyperspectral, in diverse geometric aspects will be addressed. The methods for signal processing and classification will cover concepts such as sensor adaptive and artificial neural networks, time reversal filt...

  1. Automatic design of magazine covers

    Science.gov (United States)

    Jahanian, Ali; Liu, Jerry; Tretter, Daniel R.; Lin, Qian; Damera-Venkata, Niranjan; O'Brien-Strain, Eamonn; Lee, Seungyon; Fan, Jian; Allebach, Jan P.

    2012-03-01

    In this paper, we propose a system for automatic design of magazine covers that quantifies a number of concepts from art and aesthetics. Our solution to automatic design of this type of media has been shaped by input from professional designers, magazine art directors and editorial boards, and journalists. Consequently, a number of principles in design and rules in designing magazine covers are delineated. Several techniques are derived and employed in order to quantify and implement these principles and rules in the format of a software framework. At this stage, our framework divides the task of design into three main modules: layout of magazine cover elements, choice of color for masthead and cover lines, and typography of cover lines. Feedback from professional designers on our designs suggests that our results are congruent with their intuition.

  2. The Automatic Measurement of Targets

    DEFF Research Database (Denmark)

    Höhle, Joachim

    1997-01-01

    The automatic measurement of targets is demonstrated by means of a theoretical example and by an interactive measuring program for real imagery from a réseau camera. The used strategy is a combination of two methods: the maximum correlation coefficient and the correlation in the subpixel range. F...... interactive software is also part of a computer-assisted learning program on digital photogrammetry....

  3. Automatically-Programed Machine Tools

    Science.gov (United States)

    Purves, L.; Clerman, N.

    1985-01-01

    Software produces cutter location files for numerically-controlled machine tools. APT, acronym for Automatically Programed Tools, is among most widely used software systems for computerized machine tools. APT developed for explicit purpose of providing effective software system for programing NC machine tools. APT system includes specification of APT programing language and language processor, which executes APT statements and generates NC machine-tool motions specified by APT statements.

  4. Annual review in automatic programming

    CERN Document Server

    Halpern, Mark I; Bolliet, Louis

    2014-01-01

    Computer Science and Technology and their Application is an eight-chapter book that first presents a tutorial on database organization. Subsequent chapters describe the general concepts of Simula 67 programming language; incremental compilation and conversational interpretation; dynamic syntax; the ALGOL 68. Other chapters discuss the general purpose conversational system for graphical programming and automatic theorem proving based on resolution. A survey of extensible programming language is also shown.

  5. How CBO Estimates Automatic Stabilizers

    Science.gov (United States)

    2015-11-01

    of wages and salaries and proprietors’ incomes as recorded in the NIPAs to changes in the GDP gap , CBO uses separate regressions based on equation (1...Outlays Without Automatic Stabilizers GDP Gapa Unemployment Gap (Percent)b Revenues Outlays 3 Table 1. (Continued) Deficit or Surplus With and...gross domestic product; * = between -0.05 percent and 0.05 percent. a. The GDP gap equals the difference between actual or projected GDP and CBO’s

  6. Automatic translation among spoken languages

    Science.gov (United States)

    Walter, Sharon M.; Costigan, Kelly

    1994-01-01

    The Machine Aided Voice Translation (MAVT) system was developed in response to the shortage of experienced military field interrogators with both foreign language proficiency and interrogation skills. Combining speech recognition, machine translation, and speech generation technologies, the MAVT accepts an interrogator's spoken English question and translates it into spoken Spanish. The spoken Spanish response of the potential informant can then be translated into spoken English. Potential military and civilian applications for automatic spoken language translation technology are discussed in this paper.

  7. The Automatic Galaxy Collision Software

    CERN Document Server

    Smith, Beverly J; Pfeiffer, Phillip; Perkins, Sam; Barkanic, Jason; Fritts, Steve; Southerland, Derek; Manchikalapudi, Dinikar; Baker, Matt; Luckey, John; Franklin, Coral; Moffett, Amanda; Struck, Curtis

    2009-01-01

    The key to understanding the physical processes that occur during galaxy interactions is dynamical modeling, and especially the detailed matching of numerical models to specific systems. To make modeling interacting galaxies more efficient, we have constructed the `Automatic Galaxy Collision' (AGC) code, which requires less human intervention in finding good matches to data. We present some preliminary results from this code for the well-studied system Arp 284 (NGC 7714/5), and address questions of uniqueness of solutions.

  8. Automatic computation of transfer functions

    Science.gov (United States)

    Atcitty, Stanley; Watson, Luke Dale

    2015-04-14

    Technologies pertaining to the automatic computation of transfer functions for a physical system are described herein. The physical system is one of an electrical system, a mechanical system, an electromechanical system, an electrochemical system, or an electromagnetic system. A netlist in the form of a matrix comprises data that is indicative of elements in the physical system, values for the elements in the physical system, and structure of the physical system. Transfer functions for the physical system are computed based upon the netlist.

  9. A Virtual Instrument System for Determining Sugar Degree of Honey.

    Science.gov (United States)

    Wu, Qijun; Gong, Xun

    2015-01-01

    This study established a LabVIEW-based virtual instrument system to measure optical activity through the communication of conventional optical instrument with computer via RS232 port. This system realized the functions for automatic acquisition, real-time display, data processing, results playback, and so forth. Therefore, it improved accuracy of the measurement results by avoiding the artificial operation, cumbersome data processing, and the artificial error in optical activity measurement. The system was applied to the analysis of the batch inspection on the sugar degree of honey. The results obtained were satisfying. Moreover, it showed advantages such as friendly man-machine dialogue, simple operation, and easily expanded functions.

  10. A Virtual Instrument System for Determining Sugar Degree of Honey

    Directory of Open Access Journals (Sweden)

    Qijun Wu

    2015-01-01

    Full Text Available This study established a LabVIEW-based virtual instrument system to measure optical activity through the communication of conventional optical instrument with computer via RS232 port. This system realized the functions for automatic acquisition, real-time display, data processing, results playback, and so forth. Therefore, it improved accuracy of the measurement results by avoiding the artificial operation, cumbersome data processing, and the artificial error in optical activity measurement. The system was applied to the analysis of the batch inspection on the sugar degree of honey. The results obtained were satisfying. Moreover, it showed advantages such as friendly man-machine dialogue, simple operation, and easily expanded functions.

  11. Improving polyphonic and poly-instrumental music to score alignment

    OpenAIRE

    Soulez, Ferréol; Rodet, Xavier; Schwarz, Diemo

    2003-01-01

    6pp; International audience; Music alignment links events in a score and points on the audio performance time axis. All the parts of a recording can be thus indexed according to score information. The automatic alignment presented in this paper is based on a dynamic time warping method. Local distances are computed using the signal's spectral features through an attack plus sustain note modeling. The method is applied to mixtures of harmonic sustained instruments, excluding percussion for the...

  12. Development of an automatic measuring device for total sugar content in chlortetracycline fermenter based on STM32

    Science.gov (United States)

    Liu, Ruochen; Chen, Xiangguang; Yao, Minpu; Huang, Suyi; Ma, Deshou; Zhou, Biao

    2017-01-01

    Because fermented liquid in chlortetracycline fermenter has high viscosity and complex composition, conventional instruments can't directly measure its total sugar content of fermented liquid. At present, offline artificial sampling measurement is usually the way to measuring total sugar content in chlortetracycline Fermenter. it will take too much time and manpower to finish the measurement., and the results will bring the lag of control process. To realize automatic measurement of total sugar content in chlortetracycline fermenter, we developed an automatic measuring device for total sugar content based on STM32 microcomputer. It can not only realize the function of automatic sampling, filtering, measuring of fermented liquid and automatic washing of the device, but also can make the measuring results display in the field and finish data communication. The experiment results show that the automatic measuring device of total sugar content in chlortetracycline fermenter can meet the demand of practical application.

  13. Consuming cassava as a staple food places children 2-5 years old at risk for inadequate protein intake, an observational study in Kenya and Nigeria

    Directory of Open Access Journals (Sweden)

    Gichuki Simon

    2010-02-01

    Full Text Available Abstract Background Inadequate protein intake is known to be deleterious in animals. Using WHO consensus documents for human nutrient requirements, the protein:energy ratio (P:E of an adequate diet is > 5%. Cassava has a very low protein content. This study tested the hypothesis that Nigerian and Kenyan children consuming cassava as their staple food are at greater risk for inadequate dietary protein intake than those children who consume less cassava. Methods A 24 hour dietary recall was used to determine the food and nutrient intake of 656 Nigerian and 449 Kenyan children aged 2-5 years residing in areas where cassava is a staple food. Anthropometric measurements were conducted. Diets were scored for diversity using a 12 point score. Pearson's Correlation Coefficients were calculated to relate the fraction of dietary energy obtained from cassava with protein intake, P:E, and dietary diversity. Results The fraction of dietary energy obtained from cassava was > 25% in 35% of Nigerian children and 89% of Kenyan children. The mean dietary diversity score was 4.0 in Nigerian children and 4.5 in Kenyan children, although the mean number of different foods consumed on the survey day in Nigeria was greater than Kenya, 7.0 compared to 4.6. 13% of Nigerian and 53% of Kenyan children surveyed had inadequate protein intake. The fraction of dietary energy derived from cassava was negatively correlated with protein intake, P:E, and dietary diversity. Height-for age z score was directly associated with protein intake and negatively associated with cassava consumption using regression modeling that controlled for energy and zinc intake. Conclusions Inadequate protein intake was found in the diets of Nigerian and Kenyan children consuming cassava as a staple food. Inadequate dietary protein intake is associated with stunting in this population. Interventions to increase protein intake in this vulnerable population should be the focus of future work.

  14. 混合主食的血糖生成指数研究%The glycemic index of mixed staple food.

    Institute of Scientific and Technical Information of China (English)

    胡志庚; 李伟; 周筱燕; 冯常森

    2013-01-01

    Objective To evaluate the glycemic index ( GI ) based on dietary habits according to varieties of mixed staple food. Methods According to the carbohydrate content of food to be tested, the food quantity with 50 g carbohydrate content was calculated. The 50 g of glucose was used as the contrast. Each 8 to 10 volunteers were enrolled in each tested groups, the glucose or the tested breakfast food were given the participants with fasting state. The blood glucose was measured at different time points 2 hours after breakfast for GI calculation according to Wolever calculating method. Results The GI of 17 kinds of mixed staple food were studied; among which high, median and low GI were found in 4 , 1 and 12 kinds of food, respectively. Conclusion Staple food mixed with whole - grain foods are relatively low in GI.%目的 测定混合主食的血糖生成指数(GI)值,为防治慢性代谢性疾病奠定基础.方法 根据待测食物的碳水化合物含量计算含有50 g碳水化合物的待测食物量;用50 g葡萄糖作为对照物.以10名志愿者为一个测试组,分别在空腹状态下进食葡萄糖和待测早餐食物,并测定餐后2 h内不同时点的血糖水平.根据Wolever方法计算待测食物的GI值.结果 测定了17种混合主食的GI值,其中有4种为高GI食物,1种为中GI食物,12种为低GI食物.结论 主食加入适当的粗粮可使GI降低.

  15. The keyboard instruments.

    Science.gov (United States)

    Manchester, Ralph A

    2014-06-01

    Now that the field of performing arts medicine has been in existence for over three decades, we are approaching a key point: we should start to see more articles that bring together the data that have been collected from several studies in order to draw more robust conclusions. Review articles and their more structured relative, the meta-analysis, can help to improve our understanding of a particular topic, comparing and synthesizing the results of previous research that has been done on that subject area. One way this could be done would be to review the research that has been carried out on the performance-related problems associated with playing a particular instrument or group of instruments. While I am not going to do that myself, I hope that others will. In this editorial, I will do a very selective review of the playing-related musculoskeletal disorders (PRMDs) associated with one instrument group (the keyboard instruments), focusing on the most played instrument in that group (the piano;).

  16. Biochemistry Instrumentation Core Technology Center

    Data.gov (United States)

    Federal Laboratory Consortium — The UCLA-DOE Biochemistry Instrumentation Core Facility provides the UCLA biochemistry community with easy access to sophisticated instrumentation for a wide variety...

  17. Heat Flux Instrumentation Laboratory (HFIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  18. Greenhouse gas emissions and reactive nitrogen releases during the life-cycles of staple food production in China and their mitigation potential

    Energy Technology Data Exchange (ETDEWEB)

    Xia, Longlong [State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Ti, Chaopu [State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 (China); Li, Bolun [State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Xia, Yongqiu [State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 (China); Yan, Xiaoyuan, E-mail: yanxy@issas.ac.cn [State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 (China)

    2016-06-15

    Life-cycle analysis of staple food (rice, flour and corn-based fodder) production and assessments of the associated greenhouse gas (GHG) and reactive nitrogen (Nr) releases, from environmental and economic perspectives, help to develop effective mitigation options. However, such evaluations have rarely been executed in China. We evaluated the GHG and Nr releases per kilogram of staple food production (carbon and Nr footprints) and per unit of net economic benefit (CO{sub 2-NEB} and Nr{sub -NEB}), and explored their mitigation potential. Carbon footprints of food production in China were obviously higher than those in some developed countries. There was a high spatial variation in the footprints, primarily attributable to differences in synthetic N use (or CH{sub 4} emissions) per unit of food production. Provincial carbon footprints had a significant linear relationship with Nr footprints, attributed to large contribution of N fertilizer use to both GHG and Nr releases. Synthetic N fertilizer applications and CH{sub 4} emissions dominated the carbon footprints, while NH{sub 3} volatilization and N leaching were the main contributors to the Nr footprints. About 564 (95% uncertainty range: 404–701) Tg CO{sub 2} eq GHG and 10 (7.4–12.4) Tg Nr-N were released every year during 2001–2010 from staple food production. This caused the total damage costs of 325 (70–555) billion ¥, equivalent to nearly 1.44% of the Gross Domestic Product of China. Moreover, the combined damage costs and economic input costs, accounted for 66%-80% of the gross economic benefit generated from food production. A reduction of 92.7 Tg CO{sub 2} eq yr{sup −1} and 2.2 Tg Nr-N yr{sup −1} could be achieved by reducing synthetic N inputs by 20%, increasing grain yields by 5% and implementing off-season application of straw and mid-season drainage practices for rice cultivation. In order to realize these scenarios, an ecological compensation scheme should be established to incentivize

  19. 3D Spectroscopic Instrumentation

    CERN Document Server

    Bershady, Matthew A

    2009-01-01

    In this Chapter we review the challenges of, and opportunities for, 3D spectroscopy, and how these have lead to new and different approaches to sampling astronomical information. We describe and categorize existing instruments on 4m and 10m telescopes. Our primary focus is on grating-dispersed spectrographs. We discuss how to optimize dispersive elements, such as VPH gratings, to achieve adequate spectral resolution, high throughput, and efficient data packing to maximize spatial sampling for 3D spectroscopy. We review and compare the various coupling methods that make these spectrographs ``3D,'' including fibers, lenslets, slicers, and filtered multi-slits. We also describe Fabry-Perot and spatial-heterodyne interferometers, pointing out their advantages as field-widened systems relative to conventional, grating-dispersed spectrographs. We explore the parameter space all these instruments sample, highlighting regimes open for exploitation. Present instruments provide a foil for future development. We give an...

  20. ISSUERS OF FINANCIAL INSTRUMENTS

    Directory of Open Access Journals (Sweden)

    Cristian GHEORGHE

    2016-05-01

    Full Text Available The rules laid down by Romanian Capital Market Law and the regulations put in force for its implementation apply to issuers of financial instruments admitted to trading on the regulated market established in Romania. But the issuers remain companies incorporated under Company Law of 1990. Such dual regulations need increased attention in order to observe the legal status of the issuers/companies and financial instruments/shares. Romanian legislator has chosen to implement in Capital Market Law special rules regarding the administration of the issuers of financial instruments, not only rules regarding admitting and maintaining to a regulated market. Thus issuers are, in Romanian Law perspective, special company that should comply special rule regarding board of administration and general shareholders meeting.

  1. Reconstruction of the esophagojejunostomy by double stapling method using EEA™ OrVil™ in laparoscopic total gastrectomy and proximal gastrectomy

    Directory of Open Access Journals (Sweden)

    Yano Seiji

    2011-05-01

    Full Text Available Abstract Here we report the method of anastomosis based on double stapling technique (hereinafter, DST using a trans-oral anvil delivery system (EEATM OrVilTM for reconstructing the esophagus and lifted jejunum following laparoscopic total gastrectomy or proximal gastric resection. As a basic technique, laparoscopic total gastrectomy employed Roux-en-Y reconstruction, laparoscopic proximal gastrectomy employed double tract reconstruction, and end-to-side anastomosis was used for the cut-off stump of the esophagus and lifted jejunum. We used EEATM OrVilTM as a device that permitted mechanical purse-string suture similarly to conventional EEA, and endo-Surgitie. After the gastric lymph node dissection, the esophagus was cut off using an automated stapler. EEATM OrVilTM was orally and slowly inserted from the valve tip, and a small hole was created at the tip of the obliquely cut-off stump with scissors to let the valve tip pass through. Yarn was cut to disconnect the anvil from a tube and the anvil head was retained in the esophagus. The end-Surgitie was inserted at the right subcostal margin, and after the looped-shaped thread was wrapped around the esophageal stump opening, assisting Maryland forceps inserted at the left subcostal and left abdomen were used to grasp the left and right esophageal stump. The surgeon inserted anvil grasping forceps into the right abdomen, and after grasping the esophagus with the forceps, tightened the end Surgitie, thereby completing the purse-string suture on the esophageal stump. The main unit of the automated stapler was inserted from the cut-off stump of the lifted jejunum, and a trocar was made to pass through. To prevent dropout of the small intestines from the automated stapler, the automated stapler and the lifted jejunum were fastened with silk thread, the abdomen was again inflated, and the lifted jejunum was led into the abdominal cavity. When it was confirmed that the automated stapler and center rod

  2. Virtual Sensor Test Instrumentation

    Science.gov (United States)

    Wang, Roy

    2011-01-01

    Virtual Sensor Test Instrumentation is based on the concept of smart sensor technology for testing with intelligence needed to perform sell-diagnosis of health, and to participate in a hierarchy of health determination at sensor, process, and system levels. A virtual sensor test instrumentation consists of five elements: (1) a common sensor interface, (2) microprocessor, (3) wireless interface, (4) signal conditioning and ADC/DAC (analog-to-digital conversion/ digital-to-analog conversion), and (5) onboard EEPROM (electrically erasable programmable read-only memory) for metadata storage and executable software to create powerful, scalable, reconfigurable, and reliable embedded and distributed test instruments. In order to maximize the efficient data conversion through the smart sensor node, plug-and-play functionality is required to interface with traditional sensors to enhance their identity and capabilities for data processing and communications. Virtual sensor test instrumentation can be accessible wirelessly via a Network Capable Application Processor (NCAP) or a Smart Transducer Interlace Module (STIM) that may be managed under real-time rule engines for mission-critical applications. The transducer senses the physical quantity being measured and converts it into an electrical signal. The signal is fed to an A/D converter, and is ready for use by the processor to execute functional transformation based on the sensor characteristics stored in a Transducer Electronic Data Sheet (TEDS). Virtual sensor test instrumentation is built upon an open-system architecture with standardized protocol modules/stacks to interface with industry standards and commonly used software. One major benefit for deploying the virtual sensor test instrumentation is the ability, through a plug-and-play common interface, to convert raw sensor data in either analog or digital form, to an IEEE 1451 standard-based smart sensor, which has instructions to program sensors for a wide variety of

  3. Unification of automatic target tracking and automatic target recognition

    Science.gov (United States)

    Schachter, Bruce J.

    2014-06-01

    The subject being addressed is how an automatic target tracker (ATT) and an automatic target recognizer (ATR) can be fused together so tightly and so well that their distinctiveness becomes lost in the merger. This has historically not been the case outside of biology and a few academic papers. The biological model of ATT∪ATR arises from dynamic patterns of activity distributed across many neural circuits and structures (including retina). The information that the brain receives from the eyes is "old news" at the time that it receives it. The eyes and brain forecast a tracked object's future position, rather than relying on received retinal position. Anticipation of the next moment - building up a consistent perception - is accomplished under difficult conditions: motion (eyes, head, body, scene background, target) and processing limitations (neural noise, delays, eye jitter, distractions). Not only does the human vision system surmount these problems, but it has innate mechanisms to exploit motion in support of target detection and classification. Biological vision doesn't normally operate on snapshots. Feature extraction, detection and recognition are spatiotemporal. When vision is viewed as a spatiotemporal process, target detection, recognition, tracking, event detection and activity recognition, do not seem as distinct as they are in current ATT and ATR designs. They appear as similar mechanism taking place at varying time scales. A framework is provided for unifying ATT and ATR.

  4. Standard NIM instrumentation system

    CERN Document Server

    1990-01-01

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID- 20893 (Rev 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.

  5. Virtual Reality Musical Instruments

    DEFF Research Database (Denmark)

    Serafin, Stefania; Erkut, Cumhur; Kojs, Juraj

    2016-01-01

    The rapid development and availability of low-cost technologies have created a wide interest in virtual reality. In the field of computer music, the term “virtual musical instruments” has been used for a long time to describe software simulations, extensions of existing musical instruments......, and ways to control them with new interfaces for musical expression. Virtual reality musical instruments (VRMIs) that include a simulated visual component delivered via a head-mounted display or other forms of immersive visualization have not yet received much attention. In this article, we present a field...

  6. Specification for Instrumentation

    DEFF Research Database (Denmark)

    Margheritini, Lucia; Kofoed, Jens Peter

    This paper is intended to give an overview on instrumentation for monitoring the efficiency of the Converter and the performance of the device. Real-time control of plant and data monitoring and storage are the main objectives of the control system.......This paper is intended to give an overview on instrumentation for monitoring the efficiency of the Converter and the performance of the device. Real-time control of plant and data monitoring and storage are the main objectives of the control system....

  7. Spectroelectrochemical Instrument Measures TOC

    Science.gov (United States)

    Kounaves, Sam

    2011-01-01

    A spectroelectrochemical instrument has been developed for measuring the total organic carbon (TOC) content of an aqueous solution. Measurements of TOC are frequently performed in environmental, clinical, and industrial settings. Until now, techniques for performing such measurements have included, various ly, the use of hazardous reagents, ultraviolet light, or ovens, to promote reactions in which the carbon contents are oxidized. The instrument now being developed is intended to be a safer, more economical means of oxidizing organic carbon and determining the TOC levels of aqueous solutions and for providing a low power/mass unit for use in planetary missions.

  8. Celadon Figurines Play Instruments

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    This group of figurines, each 0.15m tall, were unearthed from a Tang Dynasty tomb in Changsha in 1977. Music was very developed in the Tang Dynasty. Colorful musical instruments and dances were popular both among the people and in the palace. These vivid-looking figurines wear pleated skirts with small sleeves and open chest, a style influenced by the non-Han nationalities living in the north and west of China. Some of the musical instruments were brought from the Western Regions. The figurines are playing the xiao (a vertical bamboo flute), the konghou (an

  9. [Hardening of dental instruments].

    Science.gov (United States)

    Gerasev, G P

    1981-01-01

    The possibility of prolonging the service life of stomatological instruments by the local hardening of their working parts is discussed. Such hardening should be achieved by using hard and wear-resistant materials. The examples of hardening dental elevators and hard-alloy dental drills are given. New trends in the local hardening of instruments are the treatment of their working parts with laser beams, the application of coating on their surface by the gas-detonation method. The results of research work and trials are presented.

  10. Animation of MARDI Instrument

    Science.gov (United States)

    2008-01-01

    [figure removed for brevity, see original site] Click on image to view the animation This animation shows a zoom into the Mars Descent Imager (MARDI) instrument onboard NASA's Phoenix Mars Lander. The Phoenix team will soon attempt to use a microphone on the MARDI instrument to capture sounds of Mars. The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  11. Annual review in automatic programming

    CERN Document Server

    Goodman, Richard

    2014-01-01

    Annual Review in Automatic Programming, Volume 4 is a collection of papers that deals with the GIER ALGOL compiler, a parameterized compiler based on mechanical linguistics, and the JOVIAL language. A couple of papers describes a commercial use of stacks, an IBM system, and what an ideal computer program support system should be. One paper reviews the system of compilation, the development of a more advanced language, programming techniques, machine independence, and program transfer to other machines. Another paper describes the ALGOL 60 system for the GIER machine including running ALGOL pro

  12. On automatic machine translation evaluation

    Directory of Open Access Journals (Sweden)

    Darinka Verdonik

    2013-05-01

    Full Text Available An important task of developing machine translation (MT is evaluating system performance. Automatic measures are most commonly used for this task, as manual evaluation is time-consuming and costly. However, to perform an objective evaluation is not a trivial task. Automatic measures, such as BLEU, TER, NIST, METEOR etc., have their own weaknesses, while manual evaluations are also problematic since they are always to some extent subjective. In this paper we test the influence of a test set on the results of automatic MT evaluation for the subtitling domain. Translating subtitles is a rather specific task for MT, since subtitles are a sort of summarization of spoken text rather than a direct translation of (written text. Additional problem when translating language pair that does not include English, in our example Slovene-Serbian, is that commonly the translations are done from English to Serbian and from English to Slovenian, and not directly, since most of the TV production is originally filmed in English. All this poses additional challenges to MT and consequently to MT evaluation. Automatic evaluation is based on a reference translation, which is usually taken from an existing parallel corpus and marked as a test set. In our experiments, we compare the evaluation results for the same MT system output using three types of test set. In the first round, the test set are 4000 subtitles from the parallel corpus of subtitles SUMAT. These subtitles are not direct translations from Serbian to Slovene or vice versa, but are based on an English original. In the second round, the test set are 1000 subtitles randomly extracted from the first test set and translated anew, from Serbian to Slovenian, based solely on the Serbian written subtitles. In the third round, the test set are the same 1000 subtitles, however this time the Slovene translations were obtained by manually correcting the Slovene MT outputs so that they are correct translations of the

  13. Automatic Inference of DATR Theories

    CERN Document Server

    Barg, P

    1996-01-01

    This paper presents an approach for the automatic acquisition of linguistic knowledge from unstructured data. The acquired knowledge is represented in the lexical knowledge representation language DATR. A set of transformation rules that establish inheritance relationships and a default-inference algorithm make up the basis components of the system. Since the overall approach is not restricted to a special domain, the heuristic inference strategy uses criteria to evaluate the quality of a DATR theory, where different domains may require different criteria. The system is applied to the linguistic learning task of German noun inflection.

  14. Automatic analysis of multiparty meetings

    Indian Academy of Sciences (India)

    Steve Renals

    2011-10-01

    This paper is about the recognition and interpretation of multiparty meetings captured as audio, video and other signals. This is a challenging task since the meetings consist of spontaneous and conversational interactions between a number of participants: it is a multimodal, multiparty, multistream problem. We discuss the capture and annotation of the Augmented Multiparty Interaction (AMI) meeting corpus, the development of a meeting speech recognition system, and systems for the automatic segmentation, summarization and social processing of meetings, together with some example applications based on these systems.

  15. Commutated automatic gain control system

    Science.gov (United States)

    Yost, S. R.

    1982-01-01

    The commutated automatic gain control (AGC) system was designed and built for the prototype Loran-C receiver is discussed. The current version of the prototype receiver, the Mini L-80, was tested initially in 1980. The receiver uses a super jolt microcomputer to control a memory aided phase loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The AGC control adjusts the level of each station signal, such that the early portion of each envelope rise is about at the same amplitude in the receiver envelope detector.

  16. Coordinated hybrid automatic repeat request

    KAUST Repository

    Makki, Behrooz

    2014-11-01

    We develop a coordinated hybrid automatic repeat request (HARQ) approach. With the proposed scheme, if a user message is correctly decoded in the first HARQ rounds, its spectrum is allocated to other users, to improve the network outage probability and the users\\' fairness. The results, which are obtained for single- and multiple-antenna setups, demonstrate the efficiency of the proposed approach in different conditions. For instance, with a maximum of M retransmissions and single transmit/receive antennas, the diversity gain of a user increases from M to (J+1)(M-1)+1 where J is the number of users helping that user.

  17. Annual review in automatic programming

    CERN Document Server

    Goodman, Richard

    2014-01-01

    Annual Review in Automatic Programming, Volume 2 is a collection of papers that discusses the controversy about the suitability of COBOL as a common business oriented language, and the development of different common languages for scientific computation. A couple of papers describes the use of the Genie system in numerical calculation and analyzes Mercury autocode in terms of a phrase structure language, such as in the source language, target language, the order structure of ATLAS, and the meta-syntactical language of the assembly program. Other papers explain interference or an ""intermediate

  18. Musical Instrument Classification Based on Nonlinear Recurrence Analysis and Supervised Learning

    Directory of Open Access Journals (Sweden)

    R.Rui

    2013-04-01

    Full Text Available In this paper, the phase space reconstruction of time series produced by different instruments is discussed based on the nonlinear dynamic theory. The dense ratio, a novel quantitative recurrence parameter, is proposed to describe the difference of wind instruments, stringed instruments and keyboard instruments in the phase space by analyzing the recursive property of every instrument. Furthermore, a novel supervised learning algorithm for automatic classification of individual musical instrument signals is addressed deriving from the idea of supervised non-negative matrix factorization (NMF algorithm. In our approach, the orthogonal basis matrix could be obtained without updating the matrix iteratively, which NMF is unable to do. The experimental results indicate that the accuracy of the proposed method is improved by 3% comparing with the conventional features in the individual instrument classification.

  19. Animal experiment of memory alloy staples to control the sagittal growth of vertebrates%记忆合金加压钉抑制脊柱矢状面生长的实验研究

    Institute of Scientific and Technical Information of China (English)

    白林; 张巍; 郑国权; 张永刚

    2011-01-01

    目的 探讨记忆合金加压钉植入后非融合性抑制胸段脊柱矢状面生长的作用.方法 将18只幼年雌性山羊随机分为长钉组、短钉组、对照组各6只.长钉组和短钉组通过前路手术在前凸的T6~11胸椎节段植入记忆加压长钉(齿长7 mm)、短钉(齿长4 mm),对照组不予手术.分别于术前、术后3个月行X线片检查,测量Cobb角,对手术前后组间数据及组内自身对照数据进行统计学分析,并计算后凸增加率.大体观察被固定节段脊柱是否融合.结果 全部样本无脱失,均进入结果分析.T6~11 Cobb角,短钉组术前为7.0°±2.3°,术后3个月为12.7°±4.7°,后凸增加率为81.4%;长钉组术前为6.2°±4.0°,术后3个月为14.0°±4.9°,后凸增加率为125.8%;术前及术后长钉短钉两组组间比较,差异均无统计学意义(术前P=0.655;术后P=0.596).将长钉组和短钉组分别与对照组比较,术前差异均无统计学意义(分别为P=0.929和P=0.720);术后差异均有统计学意义(分别为P=0.007和P=0.021).大体观察证实,植入记忆合金加压钉节段脊柱未融合.结论 在山羊胸椎正前方植入记忆合金加压钉可以非融合性控制山羊胸椎的矢状面生长,增加后凸角度.%Objective To present that Nickel-Titanium (NT) memory alloy staples in fusionlessly controlling the growth of the vertebrates in the sagittal plane. Methods Eighteen infant female goats were selected and equally divided into 3 random groups:long staple group, short staple group and blank control group. Five long staple (the legs' length = 7 mm) and five short staple (the legs' length =4 mm) were implanted into each goat in long and short staple groups repecetively by anterior approach, right on the front of the thoracic vertebrae from T6 to T11. The control group was not given any treatment. X-ray examination was performed pre-operatively and post-operatively. Cobb angle of lateral radiograph was measured and the data of Cobb angle

  20. Economic Policy Instruments

    DEFF Research Database (Denmark)

    Klemmensen, Børge

    2007-01-01

    Økonomiske instrumenter begrundes med behovet for politiske indgreb, der muliggør internaliseringen af omkostningerne ved de miljøpåvirkninger, produktion and levevis afstedkommer, således at hensyntagen til miljøet bliver en del af virksomheders og husholdningers omkostninger og dermed en...

  1. Advanced instrumentation and teleoperation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    1998-07-01

    SCK-CEN's advanced instrumentation and teleoperation project aims at evaluating the potential of a telerobotic approach in a nuclear environment and, in particular, the use of remote-perception systems. Main achievements in 1997 in the areas of R and D on radiation tolerance for remote sensing, optical fibres and optical-fibre sensors, and computer-aided teleoperation are reported.

  2. Integrating Nephelometer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Uin, J. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-03-01

    The Integrating Nephelometer (Figure 1) is an instrument that measures aerosol light scattering. It measures aerosol optical scattering properties by detecting (with a wide angular integration – from 7 to 170°) the light scattered by the aerosol and subtracting the light scattered by the carrier gas, the instrument walls and the background noise in the detector (zeroing). Zeroing is typically performed for 5 minutes every day at midnight UTC. The scattered light is split into red (700 nm), green (550 nm), and blue (450 nm) wavelengths and captured by three photomultiplier tubes. The instrument can measure total scatter as well as backscatter only (from 90 to 170°) (Heintzenberg and Charlson 1996; Anderson et al. 1996; Anderson and Ogren 1998; TSI 3563 2015) At ARM (Atmospheric Radiation Measurement), two identical Nephelometers are usually run in series with a sample relative humidity (RH) conditioner between them. This is possible because Nephelometer sampling is non-destructive and the sample can be passed on to another instrument. The sample RH conditioner scans through multiple RH values in cycles, treating the sample. This kind of setup allows to study how aerosol particles’ light scattering properties are affected by humidification (Anderson et al. 1996). For historical reasons, the two Nephelometers in this setup are labeled “wet” and “dry”, with the “dry” Nephelometer usually being the one before the conditioner and sampling ambient air (the names are switched for the MAOS measurement site due to the high RH of the ambient air).

  3. The ozone monitoring instrument

    NARCIS (Netherlands)

    Levelt, P.F.; Oord, G.H.J. van den; Dobber, M.R.; Mälkki, A.; Visser, H.; Vries, J. de; Stammes, P.; Lundell, J.O.V.; Saari, H.

    2006-01-01

    The Ozone Monitoring Instrument (OMI) flies on the National Aeronautics and Space Adminsitration's Earth Observing System Aura satellite launched in July 2004. OMI is a ultraviolet/visible (UV/VIS) nadir solar backscatter spectrometer, which provides nearly global coverage in one day with a spatial

  4. Instrument for assaying radiation

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Jody Rustyn; Farfan, Eduardo B.

    2016-03-22

    An instrument for assaying radiation includes a flat panel detector having a first side opposed to a second side. A collimated aperture covers at least a portion of the first side of the flat panel detector. At least one of a display screen or a radiation shield may cover at least a portion of the second side of the flat panel detector.

  5. Neutron instrumentation for biology

    Energy Technology Data Exchange (ETDEWEB)

    Mason, S.A. [Institut Laue-Langevin, Grenoble (France)

    1994-12-31

    In the October 1994 round of proposals at the ILL, the external biology review sub- committee was asked to allocate neutron beam time to a wide range of experiments, on almost half the total number of scheduled neutron instruments: on 3 diffractometers, on 3 small angle scattering instruments, and on some 6 inelastic scattering spectrometers. In the 3.5 years since the temporary reactor shutdown, the ILL`s management structure has been optimized, budgets and staff have been trimmed, the ILL reactor has been re-built, and many of the instruments up-graded, many powerful (mainly Unix) workstations have been introduced, and the neighboring European Synchrotron Radiation Facility has established itself as the leading synchrotron radiation source and has started its official user program. The ILL reactor remains the world`s most intense dedicated neutron source. In this challenging context, it is of interest to review briefly the park of ILL instruments used to study the structure and energetics of small and large biological systems. A brief summary will be made of each class of experiments actually proposed in the latest ILL proposal round.

  6. Creating a Super Instrument

    DEFF Research Database (Denmark)

    Kallionpää, Maria; Gasselseder, Hans-Peter

    2015-01-01

    Thanks to the development of new technology, musical instruments are no more tied to their existing acoustic or technical limitations as almost all parameters can be augmented or modified in real time. An increasing number of composers, performers, and computer programmers have thus become intere...

  7. The tropospheric monitoring instrument

    NARCIS (Netherlands)

    Voert, M.J. te; Brakel, R. van; Witvoet, G.

    2014-01-01

    Thermal and opto-mechanical design and analysis work has been done on the Tropospheric Monitoring Instrument (TROPOMI), a spectrometer on the Copernicus Sentinel 5 Precursor satellite. To verify compliance with the stringent opto-mechanical stability requirements, detailed thermal and thermo-mechani

  8. Set Up of an Automatic Water Quality Sampling System in Irrigation Agriculture

    Science.gov (United States)

    Heinz, Emanuel; Kraft, Philipp; Buchen, Caroline; Frede, Hans-Georg; Aquino, Eugenio; Breuer, Lutz

    2014-05-01

    Climate change has already a large impact on the availability of water resources. Many regions in South-East Asia are assumed to receive less water in the future, dramatically impacting the production of the most important staple food: rice (Oryza sativa L.). Rice is the primary food source for nearly half of the World's population, and is the only cereal that can grow under wetland conditions. Especially anaerobic (flooded) rice fields require high amounts of water but also have higher yields than aerobic produced rice. In the past different methods were developed to reduce the water use in rice paddies, like alternative wetting and drying or the use of mixed cropping systems with aerobic (non-flooded) rice and alternative crops such as maize. A more detailed understanding of water and nutrient cycling in rice-based cropping systems is needed to reduce water use, and requires the investigation of hydrological and biochemical processes as well as transport dynamics at the field scale. New developments in analytical devices permit monitoring parameters at high temporal resolutions and at acceptable costs without much necessary maintenance or analysis over longer periods. Here we present a new type of automatic sampling set-up that facilitates in situ analysis of hydrometric information, stable water isotopes and nitrate concentrations in spatially differentiated agricultural fields. The system facilitates concurrent monitoring of a large number of water and nutrient fluxes (ground, surface, irrigation and rain water) in irrigated agriculture. For this purpose we couple an automatic sampling system with a Wavelength-Scanned Cavity Ring Down Spectrometry System (WS-CRDS) for stable water isotope analysis (δ2H and δ18O), a reagentless hyperspectral UV photometer for monitoring nitrate content and various water level sensors for hydrometric information. The whole system is maintained with special developed software for remote control of the system via internet. We

  9. SU-E-J-129: Atlas Development for Cardiac Automatic Contouring Using Multi-Atlas Segmentation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, R; Yang, J; Pan, T; Milgrom, S; Pinnix, C; Shi, A; Yang, J; Liu, Y; Nguyen, Q; Gomez, D; Dabaja, B; Balter, P; Court, L; Liao, Z [MD Anderson Cancer Center, Houston, TX (United States)

    2015-06-15

    Purpose: To develop a set of atlases for automatic contouring of cardiac structures to determine heart radiation dose and the associated toxicity. Methods: Six thoracic cancer patients with both contrast and non-contrast CT images were acquired for this study. Eight radiation oncologists manually and independently delineated cardiac contours on the non-contrast CT by referring to the fused contrast CT and following the RTOG 1106 atlas contouring guideline. Fifteen regions of interest (ROIs) were delineated, including heart, four chambers, four coronary arteries, pulmonary artery and vein, inferior and superior vena cava, and ascending and descending aorta. Individual expert contours were fused using the simultaneous truth and performance level estimation (STAPLE) algorithm for each ROI and each patient. The fused contours became atlases for an in-house multi-atlas segmentation. Using leave-one-out test, we generated auto-segmented contours for each ROI and each patient. The auto-segmented contours were compared with the fused contours using the Dice similarity coefficient (DSC) and the mean surface distance (MSD). Results: Inter-observer variability was not obvious for heart, chambers, and aorta but was large for other structures that were not clearly distinguishable on CT image. The average DSC between individual expert contours and the fused contours were less than 50% for coronary arteries and pulmonary vein, and the average MSD were greater than 4.0 mm. The largest MSD of expert contours deviating from the fused contours was 2.5 cm. The mean DSC and MSD of auto-segmented contours were within one standard deviation of expert contouring variability except the right coronary artery. The coronary arteries, vena cava, and pulmonary vein had DSC<70% and MSD>3.0 mm. Conclusion: A set of cardiac atlases was created for cardiac automatic contouring, the accuracy of which was comparable to the variability in expert contouring. However, substantial modification may need

  10. The Science of String Instruments

    CERN Document Server

    Rossing, Thomas D

    2010-01-01

    Many performing musicians, as well as instrument builders, are coming to realize the importance of understanding the science of musical instruments. This book explains how string instruments produce sound. It presents basic ideas in simple language, and it also translates some more sophisticated ideas in non-technical language. It should be of interest to performers, researchers, and instrument makers alike.

  11. Automatic generation of tourist brochures

    KAUST Repository

    Birsak, Michael

    2014-05-01

    We present a novel framework for the automatic generation of tourist brochures that include routing instructions and additional information presented in the form of so-called detail lenses. The first contribution of this paper is the automatic creation of layouts for the brochures. Our approach is based on the minimization of an energy function that combines multiple goals: positioning of the lenses as close as possible to the corresponding region shown in an overview map, keeping the number of lenses low, and an efficient numbering of the lenses. The second contribution is a route-aware simplification of the graph of streets used for traveling between the points of interest (POIs). This is done by reducing the graph consisting of all shortest paths through the minimization of an energy function. The output is a subset of street segments that enable traveling between all the POIs without considerable detours, while at the same time guaranteeing a clutter-free visualization. © 2014 The Author(s) Computer Graphics Forum © 2014 The Eurographics Association and John Wiley & Sons Ltd. Published by John Wiley & Sons Ltd.

  12. Automatic Control of Water Pumping Stations

    Institute of Scientific and Technical Information of China (English)

    Muhannad Alrheeh; JIANG Zhengfeng

    2006-01-01

    Automatic Control of pumps is an interesting proposal to operate water pumping stations among many kinds of water pumping stations according to their functions.In this paper, our pumping station is being used for water supply system. This paper is to introduce the idea of pump controller and the important factors that must be considering when we want to design automatic control system of water pumping stations. Then the automatic control circuit with the function of all components will be introduced.

  13. Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment.

    Science.gov (United States)

    Slootweg, Jack C; Peters, Nienke; Quarles van Ufford, H Linda C; Breukink, Eefjan; Liskamp, Rob M J; Rijkers, Dirk T S

    2014-10-01

    The antimicrobial peptide nisin is a promising template for designing novel peptide-based antibiotics to improve its drug-like properties. First steps in that direction represent the synthesis of hybrid nisin derivatives that contain a native nisin ABC-part and synthesized cross-stapled DE-ring fragments and are described here. The biological activity of the newly synthesized nisin derivatives was evaluated in order to compare the bioactivity of the synthetic DE-ring containing mimic and native lanthionine-bridged DE-ring containing nisin. The native nisin ABC-ring system was obtained via chymotrypsin digestion of full-length nisin, and was subsequently functionalized at the C-terminal carboxylate with two different amino alkyne moieties. Next, nisin hybrids were successfully prepared using Cu(I)-catalyzed azide alkyne cycloaddition 'click' chemistry by chemo-selective ligation of the ABC-alkyne with the N-terminal azido functionalized dicarba-DE ring mimic. The newly synthesized compounds were active as potent lipid II binders and retained antimicrobial activity in a growth inhibition assay. However, pore formation was not observed, possibly either due to the different character of the 'staples' as compared to the parent sulfides, or due to the triazole moiety as a sub-optimal amide bond isostere.

  14. Glycaemic index and load values tested in normoglycemic adults for five staple foodstuffs: pounded yam, pounded cassava-plantain, placali, attieke and maize meal stiff porridge.

    Science.gov (United States)

    Kouamé, Adam C; Kouassi, Kouakou N; N'dri, Yao D; Amani, N'guessan G

    2015-02-16

    There is currently an increased global interest in the published glycaemic index (GI) and glycaemic load (GL) values of foods. However, data on the GI and GL values of different varieties of foods within Côte d'Ivoire are very limited. The study therefore aimed at finding the GI and GL of the main food staples in Côte d'Ivoire. Following the International Standard Organisation's protocol (ISO/FDI 26642:2010), a selection of five staple foodstuffs were tested for their GI and GL. Fasted healthy subjects were given 50 g of available carbohydrate servings of a glucose reference, which was tested twice, and test foods which were tested once, on separate occasions. Excepted attieke (GI 63), the majority of foods tested have a high GI (GI>70). Attieke (agbodjama) had a high GL (GL 29) while placali (GL 17) and maize meal stiff porridge (GL 16) had medium GLs. The GLs of pounded cassava-plantain and pounded yam are 26 and 22. Consumption of attieke could minimize postprandial blood glucose spikes, in spite of high GL and potentially have benefit in the management and prevention of some chronic diseases.

  15. Glycaemic Index and Load Values Tested in Normoglycemic Adults for Five Staple Foodstuffs: Pounded Yam, Pounded Cassava-Plantain, Placali, Attieke and Maize Meal Stiff Porridge

    Directory of Open Access Journals (Sweden)

    Adam C. Kouamé

    2015-02-01

    Full Text Available There is currently an increased global interest in the published glycaemic index (GI and glycaemic load (GL values of foods. However, data on the GI and GL values of different varieties of foods within Côte d’Ivoire are very limited. The study therefore aimed at finding the GI and GL of the main food staples in Côte d’Ivoire. Following the International Standard Organisation’s protocol (ISO/FDI 26642:2010, a selection of five staple foodstuffs were tested for their GI and GL. Fasted healthy subjects were given 50 g of available carbohydrate servings of a glucose reference, which was tested twice, and test foods which were tested once, on separate occasions. Excepted attieke (GI 63, the majority of foods tested have a high GI (GI > 70. Attieke (agbodjama had a high GL (GL 29 while placali (GL 17 and maize meal stiff porridge (GL 16 had medium GLs. The GLs of pounded cassava-plantain and pounded yam are 26 and 22. Consumption of attieke could minimize postprandial blood glucose spikes, in spite of high GL and potentially have benefit in the management and prevention of some chronic diseases.

  16. Laparoscopic assisted radical cystoprostatectomy with Y-shaped orthotopic ileal neobladder constructed with non-absorbable titanium staples through a 5 cm Pfannensteil incision

    Directory of Open Access Journals (Sweden)

    Sidney C. Abreu

    2005-08-01

    Full Text Available INTRODUCTION: We performed a laparoscopic radical cystoprostatectomy followed by constructing a Y-shaped reservoir extra-corporeally with titanium staples through a 5-cm muscle-splitting Pfannenstiel incision. SURGICAL TECHNIQUE: Upon completion of the extirpative part of the operation, the surgical specimen was entrapped and removed intact through a 5-cm Pfannenstiel incision. Through the extraction incision, the distal ileum was identified and a 40 cm segment isolated. With the aid of the laparoscope, the ureters were brought outside the abdominal cavity and freshened and spatulated for approximately 1.5-cm. Bilateral double J ureteral stents were then inserted up to the renal pelvis and the ureters were directly anastomosed to the open ends of the limbs of the neobladder. Following this, the isolated intestinal segment was arranged in a Y shape with two central segments of 14 cm and two limbs of 6 cm. The two central segments were brought together and detubularized, with two sequential firings of 80 x 3.5 mm and 60 x 3.5 mm non-absorbable mechanical stapler (Multifire GIA - US Surgical inserted through an opening made at the lowest point of the neobladder on its anti-mesenteric border. The neobladder was reinserted inside the abdominal cavity and anastomosed to the urethra with intracorporeal laparoscopic free-hand suturing. CONCLUSION: Although this procedure is feasible and the preliminary results encouraging, continued surveillance is necessary to determine the lithiasis-inducing potential of these titanium staples within the urinary tract.

  17. Pelvic flexure enterotomy closure in the horse with a TA-90 stapling device: a retrospective clinical study of 84 cases (2001-2008).

    Science.gov (United States)

    Rosser, Julie; Brounts, Sabrina; Slone, Don; Lynch, Tim; Livesey, Michael; Hughes, Faith; Clark, Carol

    2012-06-01

    Our objective was to compare survival and complication rates of horses undergoing pelvic flexure enterotomy closure with a TA-90 stapler to those with hand-sewn closure. Medical records of horses undergoing pelvic flexure enterotomy between 2001 and 2008 were reviewed. History, clinical signs, surgical findings, surgical techniques, and post-operative complications were recorded. Long-term outcome was established by telephone questionnaire. Of 84 pelvic flexure enterotomies performed, 70 were stapled and 14 were hand-sewn. Seventy-seven horses survived to discharge (91.7%). There were no significant associations between survival and closure technique (P = 0.69). Follow-up was available for 54 horses; 50 survived long-term (93.0%). No statistical significance was identified between long-term survival and closure method (P = 0.39). Forty horses went on to athletic performance (80.0%). TA-90 stapled closure of pelvic flexure enterotomies is a safe technique resulting in survival and complication rates equivalent to those of hand-sewn closure.

  18. Ontology Based Vocabulary Matching for Oceanographic Instruments

    Science.gov (United States)

    Chen, Yu; Shepherd, Adam; Chandler, Cyndy; Arko, Robert; Leadbetter, Adam

    2014-05-01

    Data integration act as the preliminary entry point as we enter the era of big data in many scientific domains. However the reusefulness of various dataset has met the hurdle due to different initial of interests of different parties, therefore different vocabularies in describing similar or semantically related concepts. In this scenario it is vital to devise an automatic or semi-supervised algorithm to facilitate the convergence of different vocabularies. The Ocean Data Interoperability Platform (ODIP) seeks to increase data sharing across scientific domains and international boundaries by providing a forum to harmonize diverse regional data systems. ODIP participants from the US include the Rolling Deck to Repository (R2R) program, whose mission is to capture, catalog, and describe the underway/environmental sensor data from US oceanographic research vessels and submit the data to public long-term archives. In an attempt to harmonize these regional data systems, especially vocabularies, R2R recognizes the value of the SeaDataNet vocabularies served by the NERC Vocabulary Server (NVS) hosted at the British Oceanographic Data Centre as a trusted, authoritative source for describing many oceanographic research concepts such as instrumentation. In this work, we make use of the semantic relations in the vocabularies served by NVS to build a Bayesian network and take advantage of the idea of entropy in evaluating the correlation between different concepts and keywords. The performance of the model is evaluated against matching instruments from R2R against the SeaDataNet instrument vocabularies based on calculated confidence scores in the instrument pairings. These pairings with their scores can then be analyzed for assertion growing the interoperability of the R2R vocabulary through its links to the SeaDataNet entities.

  19. The research and development of dry spinning complete equipment for melamine staple fiber%蜜胺短纤维干法纺丝成套设备的研发

    Institute of Scientific and Technical Information of China (English)

    高占勇

    2012-01-01

    简要介绍了蜜胺纤维的性能特点及主要技术参数。从机械设备角度分析、探讨了蜜胺短纤维干法纺丝生产线的配置,分析了纺丝及后处理设备的结构特点。%The performance characteristics and main technical parameters of melamine staple fiber were introduced briefly. Dry spinning production line configuration and spinning as well as post-processing equipment struc- ture for the melamine staple fiber were analyzed from the perspective of equipment.

  20. netherland hydrological modeling instrument

    Science.gov (United States)

    Hoogewoud, J. C.; de Lange, W. J.; Veldhuizen, A.; Prinsen, G.

    2012-04-01

    Netherlands Hydrological Modeling Instrument A decision support system for water basin management. J.C. Hoogewoud , W.J. de Lange ,A. Veldhuizen , G. Prinsen , The Netherlands Hydrological modeling Instrument (NHI) is the center point of a framework of models, to coherently model the hydrological system and the multitude of functions it supports. Dutch hydrological institutes Deltares, Alterra, Netherlands Environmental Assessment Agency, RWS Waterdienst, STOWA and Vewin are cooperating in enhancing the NHI for adequate decision support. The instrument is used by three different ministries involved in national water policy matters, for instance the WFD, drought management, manure policy and climate change issues. The basis of the modeling instrument is a state-of-the-art on-line coupling of the groundwater system (MODFLOW), the unsaturated zone (metaSWAP) and the surface water system (MOZART-DM). It brings together hydro(geo)logical processes from the column to the basin scale, ranging from 250x250m plots to the river Rhine and includes salt water flow. The NHI is validated with an eight year run (1998-2006) with dry and wet periods. For this run different parts of the hydrology have been compared with measurements. For instance, water demands in dry periods (e.g. for irrigation), discharges at outlets, groundwater levels and evaporation. A validation alone is not enough to get support from stakeholders. Involvement from stakeholders in the modeling process is needed. There fore to gain sufficient support and trust in the instrument on different (policy) levels a couple of actions have been taken: 1. a transparent evaluation of modeling-results has been set up 2. an extensive program is running to cooperate with regional waterboards and suppliers of drinking water in improving the NHI 3. sharing (hydrological) data via newly setup Modeling Database for local and national models 4. Enhancing the NHI with "local" information. The NHI is and has been used for many

  1. An Electronic Measurement Instrumentation of the Impedance of a Loaded Fuel Cell or Battery

    OpenAIRE

    2007-01-01

    In this paper we present an inexpensive electronic measurement instrumentation developed in our laboratory, to measure and plot the impedance of a loaded fuel cell or battery. Impedance measurements were taken by using the load modulation method. This instrumentation has been developed around a VXI system stand which controls electronic cards. Software under Hpvee® was developed for automatic measurements and the layout of the impedance of the fuel cell on load. The measurement environment, l...

  2. DAS: a data management system for instrument tests and operations

    CERN Document Server

    Frailis, Marco; Zacchei, Andrea; Lodi, Marcello; Cirami, Roberto; Pasian, Fabio; Trifoglio, Massimo; Bulgarelli, Andrea; Gianotti, Fulvio; Franceschi, Enrico; Nicastro, Luciano; Conforti, Vito; Zoli, Andrea; Smart, Ricky; Morbidelli, Roberto; Dadina, Mauro

    2014-01-01

    The Data Access System (DAS) is a metadata and data management software system, providing a reusable solution for the storage of data acquired both from telescopes and auxiliary data sources during the instrument development phases and operations. It is part of the Customizable Instrument WorkStation system (CIWS-FW), a framework for the storage, processing and quick-look at the data acquired from scientific instruments. The DAS provides a data access layer mainly targeted to software applications: quick-look displays, pre-processing pipelines and scientific workflows. It is logically organized in three main components: an intuitive and compact Data Definition Language (DAS DDL) in XML format, aimed for user-defined data types; an Application Programming Interface (DAS API), automatically adding classes and methods supporting the DDL data types, and providing an object-oriented query language; a data management component, which maps the metadata of the DDL data types in a relational Data Base Management Syste...

  3. Data acquisition instruments: Psychopharmacology

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, D.S. III

    1998-01-01

    This report contains the results of a Direct Assistance Project performed by Lockheed Martin Energy Systems, Inc., for Dr. K. O. Jobson. The purpose of the project was to perform preliminary analysis of the data acquisition instruments used in the field of psychiatry, with the goal of identifying commonalities of data and strategies for handling and using the data in the most advantageous fashion. Data acquisition instruments from 12 sources were provided by Dr. Jobson. Several commonalities were identified and a potentially useful data strategy is reported here. Analysis of the information collected for utility in performing diagnoses is recommended. In addition, further work is recommended to refine the commonalities into a directly useful computer systems structure.

  4. KEKB beam instrumentation systems

    Science.gov (United States)

    Arinaga, M.; Flanagan, J.; Hiramatsu, S.; Ieiri, T.; Ikeda, H.; Ishii, H.; Kikutani, E.; Mimashi, T.; Mitsuhashi, T.; Mizuno, H.; Mori, K.; Tejima, M.; Tobiyama, M.

    2003-02-01

    For the stable high-luminosity operation and luminosity increase, the electron and positron storage rings of the KEK B-Factory (KEKB) is equipped with various beam instrumentations, which have been working well since the start of the commissioning in December, 1998. Details and performance of the beam-position monitor system based on the spectrum analysis using DSPs, the turn-by-turn BPM with four-dimensional function available for measurements of the individual bunch position, phase and intensity, the parametric beam-DCCTs designed so as to avoid the magnetic-core-selection problems for the parametric flux modulation, the bunch-by-bunch feedback system indispensable to suppress the strong multibunch instabilities in KEKB, the various optical beam diagnostic systems, such as synchrotron radiation interferometers for precise beam-size measurement, the tune meters, the bunch length monitors and the beam-loss monitors are described. Delicate machine tuning of KEKB is strongly supported by these instrumentations.

  5. Solar radioastronomical instruments

    Science.gov (United States)

    Gonze, R.

    Instruments for detecting and recording the radio emissions of the sun are required to cover the entire electromagnetic spectrum, measure intensity and polarization, as well as the region of the emissions, and display high resolution in both space and time. Radioheliographic images of the sun are made from wavelengths outside of the visible, and yield images based on a grid of relative intensities of varying fineness of resolution. Radioelectric isophote contours can be generated using radiotelescopes at specific receptive frequencies, and interferometric techniques permit the employment of multiple paraboloidal receivers to construct a synthetic image of greater resolution than possible with a single antenna. Dynamic radiospectrography is used to examine transitory solar radio emissions where fine structures are produced in frequency bands covering at least an octave. Multichannel radiospectrographic equipment with many receptors tuned to discrete frequencies and regularly adjusted permits coverage of broad frequency bands, with digital control to augment the dynamics of the instruments.

  6. Instrumentation problems for physicians.

    Science.gov (United States)

    Turner, G O

    1980-01-01

    The physician has, for whatever reasons, diminished his or her level of involvement on the team dedicated to developing, refining, and evaluating medical technology. As a result, the challenge confronting the physician and the technology development team today is to orchestrate a team structure that will ensure the greatest input and commitment from physicians and other professionals during current and future technology development. The charges of cost escalation and dehumanization in our system of health care delivery will also be discussed, as will the lack of, or confusion about, access to data concerning cost of a given instrument, and fuzzy semantics and perspectives on technology and instrumentation. The author suggests answers to, or means to ameliorate, the problems.

  7. Automatic Network Reconstruction using ASP

    CERN Document Server

    Ostrowski, Max; Durzinsky, Markus; Marwan, Wolfgang; Wagler, Annegret

    2011-01-01

    Building biological models by inferring functional dependencies from experimental data is an im- portant issue in Molecular Biology. To relieve the biologist from this traditionally manual process, various approaches have been proposed to increase the degree of automation. However, available ap- proaches often yield a single model only, rely on specific assumptions, and/or use dedicated, heuris- tic algorithms that are intolerant to changing circumstances or requirements in the view of the rapid progress made in Biotechnology. Our aim is to provide a declarative solution to the problem by ap- peal to Answer Set Programming (ASP) overcoming these difficulties. We build upon an existing approach to Automatic Network Reconstruction proposed by part of the authors. This approach has firm mathematical foundations and is well suited for ASP due to its combinatorial flavor providing a characterization of all models explaining a set of experiments. The usage of ASP has several ben- efits over the existing heuristic a...

  8. Automatic validation of numerical solutions

    DEFF Research Database (Denmark)

    Stauning, Ole

    1997-01-01

    This thesis is concerned with ``Automatic Validation of Numerical Solutions''. The basic theory of interval analysis and self-validating methods is introduced. The mean value enclosure is applied to discrete mappings for obtaining narrow enclosures of the iterates when applying these mappings...... is the possiblility to combine the three methods in an extremely flexible way. We examine some applications where this flexibility is very useful. A method for Taylor expanding solutions of ordinary differential equations is presented, and a method for obtaining interval enclosures of the truncation errors incurred...... with intervals as initial values. A modification of the mean value enclosure of discrete mappings is considered, namely the extended mean value enclosure which in most cases leads to even better enclosures. These methods have previously been described in connection with discretizing solutions of ordinary...

  9. Automatic summarising factors and directions

    CERN Document Server

    Jones, K S

    1998-01-01

    This position paper suggests that progress with automatic summarising demands a better research methodology and a carefully focussed research strategy. In order to develop effective procedures it is necessary to identify and respond to the context factors, i.e. input, purpose, and output factors, that bear on summarising and its evaluation. The paper analyses and illustrates these factors and their implications for evaluation. It then argues that this analysis, together with the state of the art and the intrinsic difficulty of summarising, imply a nearer-term strategy concentrating on shallow, but not surface, text analysis and on indicative summarising. This is illustrated with current work, from which a potentially productive research programme can be developed.

  10. Autoclass: An automatic classification system

    Science.gov (United States)

    Stutz, John; Cheeseman, Peter; Hanson, Robin

    1991-01-01

    The task of inferring a set of classes and class descriptions most likely to explain a given data set can be placed on a firm theoretical foundation using Bayesian statistics. Within this framework, and using various mathematical and algorithmic approximations, the AutoClass System searches for the most probable classifications, automatically choosing the number of classes and complexity of class descriptions. A simpler version of AutoClass has been applied to many large real data sets, has discovered new independently-verified phenomena, and has been released as a robust software package. Recent extensions allow attributes to be selectively correlated within particular classes, and allow classes to inherit, or share, model parameters through a class hierarchy. The mathematical foundations of AutoClass are summarized.

  11. Impact dynamics instrumentation

    Science.gov (United States)

    Mccormck, R. F.

    1986-01-01

    One of the tasks specified in the NASA Langley controlled impact demonstration (CID) work package was to furnish dynamic instrumentation sensors. The types of instrumentation sensors required were accelerometers for aircraft structural loads measurements, seat belt load cells to measure anthropomorphic dummy responses to the aircraft impact, and strain gage bending bridges to measure the aircraft fuselage and wing bending during impact. The objective in the selection of dynamic instrumentation for the CID was to provide 352 of the highest quality transducers and remain within budget allocation. The transducers that were selected for the CID evaluation process were each subjected to rigorous laboratory acceptance tests and to aircraft fuselage section drop tests at the LaRC Impact Dynamics Research Facility. Data compiled from this series of tests showed the selected transducers to be best suited for the CID mission requirement. The transducers installation technique on the airframe proved successful. The transducer quality assurance was guaranteed through rigorous acceptance testing. Data acquired was 97.0%.

  12. An ice lithography instrument

    Science.gov (United States)

    Han, Anpan; Chervinsky, John; Branton, Daniel; Golovchenko, J. A.

    2011-06-01

    We describe the design of an instrument that can fully implement a new nanopatterning method called ice lithography, where ice is used as the resist. Water vapor is introduced into a scanning electron microscope (SEM) vacuum chamber above a sample cooled down to 110 K. The vapor condenses, covering the sample with an amorphous layer of ice. To form a lift-off mask, ice is removed by the SEM electron beam (e-beam) guided by an e-beam lithography system. Without breaking vacuum, the sample with the ice mask is then transferred into a metal deposition chamber where metals are deposited by sputtering. The cold sample is then unloaded from the vacuum system and immersed in isopropanol at room temperature. As the ice melts, metal deposited on the ice disperses while the metals deposited on the sample where the ice had been removed by the e-beam remains. The instrument combines a high beam-current thermal field emission SEM fitted with an e-beam lithography system, cryogenic systems, and a high vacuum metal deposition system in a design that optimizes ice lithography for high throughput nanodevice fabrication. The nanoscale capability of the instrument is demonstrated with the fabrication of nanoscale metal lines.

  13. Endoscopic vision-based tracking of multiple surgical instruments during robot-assisted surgery.

    Science.gov (United States)

    Ryu, Jiwon; Choi, Jaesoon; Kim, Hee Chan

    2013-01-01

    Robot-assisted minimally invasive surgery is effective for operations in limited space. Enhancing safety based on automatic tracking of surgical instrument position to prevent inadvertent harmful events such as tissue perforation or instrument collisions could be a meaningful augmentation to current robotic surgical systems. A vision-based instrument tracking scheme as a core algorithm to implement such functions was developed in this study. An automatic tracking scheme is proposed as a chain of computer vision techniques, including classification of metallic properties using k-means clustering and instrument movement tracking using similarity measures, Euclidean distance calculations, and a Kalman filter algorithm. The implemented system showed satisfactory performance in tests using actual robot-assisted surgery videos. Trajectory comparisons of automatically detected data and ground truth data obtained by manually locating the center of mass of each instrument were used to quantitatively validate the system. Instruments and collisions could be well tracked through the proposed methods. The developed collision warning system could provide valuable information to clinicians for safer procedures.

  14. FHR Process Instruments

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, David Eugene [ORNL

    2015-01-01

    Fluoride salt-cooled High temperature Reactors (FHRs) are entering into early phase engineering development. Initial candidate technologies have been identified to measure all of the required process variables. The purpose of this paper is to describe the proposed measurement techniques in sufficient detail to enable assessment of the proposed instrumentation suite and to support development of the component technologies. This paper builds upon the instrumentation chapter of the recently published FHR technology development roadmap. Locating instruments outside of the intense core radiation and high-temperature fluoride salt environment significantly decreases their environmental tolerance requirements. Under operating conditions, FHR primary coolant salt is a transparent, low-vapor-pressure liquid. Consequently, FHRs can employ standoff optical measurements from above the salt pool to assess in-vessel conditions. For example, the core outlet temperature can be measured by observing the fuel s blackbody emission. Similarly, the intensity of the core s Cerenkov glow indicates the fission power level. Short-lived activation of the primary coolant provides another means for standoff measurements of process variables. The primary coolant flow and neutron flux can be measured using gamma spectroscopy along the primary coolant piping. FHR operation entails a number of process measurements. Reactor thermal power and core reactivity are the most significant variables for process control. Thermal power can be determined by measuring the primary coolant mass flow rate and temperature rise across the core. The leading candidate technologies for primary coolant temperature measurement are Au-Pt thermocouples and Johnson noise thermometry. Clamp-on ultrasonic flow measurement, that includes high-temperature tolerant standoffs, is a potential coolant flow measurement technique. Also, the salt redox condition will be monitored as an indicator of its corrosiveness. Both

  15. Solar Powered Automatic Shrimp Feeding System

    Directory of Open Access Journals (Sweden)

    Dindo T. Ani

    2015-12-01

    Full Text Available - Automatic system has brought many revolutions in the existing technologies. One among the technologies, which has greater developments, is the solar powered automatic shrimp feeding system. For instance, the solar power which is a renewable energy can be an alternative solution to energy crisis and basically reducing man power by using it in an automatic manner. The researchers believe an automatic shrimp feeding system may help solve problems on manual feeding operations. The project study aimed to design and develop a solar powered automatic shrimp feeding system. It specifically sought to prepare the design specifications of the project, to determine the methods of fabrication and assembly, and to test the response time of the automatic shrimp feeding system. The researchers designed and developed an automatic system which utilizes a 10 hour timer to be set in intervals preferred by the user and will undergo a continuous process. The magnetic contactor acts as a switch connected to the 10 hour timer which controls the activation or termination of electrical loads and powered by means of a solar panel outputting electrical power, and a rechargeable battery in electrical communication with the solar panel for storing the power. By undergoing through series of testing, the components of the modified system were proven functional and were operating within the desired output. It was recommended that the timer to be used should be tested to avoid malfunction and achieve the fully automatic system and that the system may be improved to handle changes in scope of the project.

  16. Automatic cobb angle determination from radiographic images

    NARCIS (Netherlands)

    Sardjono, Tri Arief; Wilkinson, Michael H.F.; Veldhuizen, Albert G.; Ooijen, van Peter M.A.; Purnama, Ketut E.; Verkerke, Gijsbertus J.

    2013-01-01

    Study Design. Automatic measurement of Cobb angle in patients with scoliosis. Objective. To test the accuracy of an automatic Cobb angle determination method from frontal radiographical images. Summary of Background Data. Thirty-six frontal radiographical images of patients with scoliosis. Met

  17. Automatic Cobb Angle Determination From Radiographic Images

    NARCIS (Netherlands)

    Sardjono, Tri Arief; Wilkinson, Michael H. F.; Veldhuizen, Albert G.; van Ooijen, Peter M. A.; Purnama, Ketut E.; Verkerke, Gijsbertus J.

    2013-01-01

    Study Design. Automatic measurement of Cobb angle in patients with scoliosis. Objective. To test the accuracy of an automatic Cobb angle determination method from frontal radiographical images. Summary of Background Data. Thirty-six frontal radiographical images of patients with scoliosis. Methods.

  18. Optical Methods For Automatic Rating Of Engine Test Components

    Science.gov (United States)

    Pritchard, James R.; Moss, Brian C.

    1989-03-01

    In recent years, increasing commercial and legislative pressure on automotive engine manufacturers, including increased oil drain intervals, cleaner exhaust emissions and high specific power outputs, have led to increasing demands on lubricating oil performance. Lubricant performance is defined by bench engine tests run under closely controlled conditions. After test, engines are dismantled and the parts rated for wear and accumulation of deposit. This rating must be consistently carried out in laboratories throughout the world in order to ensure lubricant quality meeting the specified standards. To this end, rating technicians evaluate components, following closely defined procedures. This process is time consuming, inaccurate and subject to drift, requiring regular recalibration of raters by means of international rating workshops. This paper describes two instruments for automatic rating of engine parts. The first uses a laser to determine the degree of polishing of the engine cylinder bore, caused by the reciprocating action of piston. This instrument has been developed to prototype stage by the NDT Centre at Harwell under contract to Exxon Chemical, and is planned for production within the next twelve months. The second instrument uses red and green filtered light to determine the type, quality and position of deposit formed on the piston surfaces. The latter device has undergone feasibility study, but no prototype exists.

  19. CARMENES instrument overview

    Science.gov (United States)

    Quirrenbach, A.; Amado, P. J.; Caballero, J. A.; Mundt, R.; Reiners, A.; Ribas, I.; Seifert, W.; Abril, M.; Aceituno, J.; Alonso-Floriano, F. J.; Ammler-von Eiff, M.; Antona Jiménez, R.; Anwand-Heerwart, H.; Azzaro, M.; Bauer, F.; Barrado, D.; Becerril, S.; Béjar, V. J. S.; Benítez, D.; Berdiñas, Z. M.; Cárdenas, M. C.; Casal, E.; Claret, A.; Colomé, J.; Cortés-Contreras, M.; Czesla, S.; Doellinger, M.; Dreizler, S.; Feiz, C.; Fernández, M.; Galadí, D.; Gálvez-Ortiz, M. C.; García-Piquer, A.; García-Vargas, M. L.; Garrido, R.; Gesa, L.; Gómez Galera, V.; González Álvarez, E.; González Hernández, J. I.; Grözinger, U.; Guàrdia, J.; Guenther, E. W.; de Guindos, E.; Gutiérrez-Soto, J.; Hagen, H.-J.; Hatzes, A. P.; Hauschildt, P. H.; Helmling, J.; Henning, T.; Hermann, D.; Hernández Castaño, L.; Herrero, E.; Hidalgo, D.; Holgado, G.; Huber, A.; Huber, K. F.; Jeffers, S.; Joergens, V.; de Juan, E.; Kehr, M.; Klein, R.; Kürster, M.; Lamert, A.; Lalitha, S.; Laun, W.; Lemke, U.; Lenzen, R.; López del Fresno, Mauro; López Martí, B.; López-Santiago, J.; Mall, U.; Mandel, H.; Martín, E. L.; Martín-Ruiz, S.; Martínez-Rodríguez, H.; Marvin, C. J.; Mathar, R. J.; Mirabet, E.; Montes, D.; Morales Muñoz, R.; Moya, A.; Naranjo, V.; Ofir, A.; Oreiro, R.; Pallé, E.; Panduro, J.; Passegger, V.-M.; Pérez-Calpena, A.; Pérez Medialdea, D.; Perger, M.; Pluto, M.; Ramón, A.; Rebolo, R.; Redondo, P.; Reffert, S.; Reinhardt, S.; Rhode, P.; Rix, H.-W.; Rodler, F.; Rodríguez, E.; Rodríguez-López, C.; Rodríguez-Pérez, E.; Rohloff, R.-R.; Rosich, A.; Sánchez-Blanco, E.; Sánchez Carrasco, M. A.; Sanz-Forcada, J.; Sarmiento, L. F.; Schäfer, S.; Schiller, J.; Schmidt, C.; Schmitt, J. H. M. M.; Solano, E.; Stahl, O.; Storz, C.; Stürmer, J.; Suárez, J. C.; Ulbrich, R. G.; Veredas, G.; Wagner, K.; Winkler, J.; Zapatero Osorio, M. R.; Zechmeister, M.; Abellán de Paco, F. J.; Anglada-Escudé, G.; del Burgo, C.; Klutsch, A.; Lizon, J. L.; López-Morales, M.; Morales, J. C.; Perryman, M. A. C.; Tulloch, S. M.; Xu, W.

    2014-07-01

    This paper gives an overview of the CARMENES instrument and of the survey that will be carried out with it during the first years of operation. CARMENES (Calar Alto high-Resolution search for M dwarfs with Exoearths with Near-infrared and optical Echelle Spectrographs) is a next-generation radial-velocity instrument under construction for the 3.5m telescope at the Calar Alto Observatory by a consortium of eleven Spanish and German institutions. The scientific goal of the project is conducting a 600-night exoplanet survey targeting ~ 300 M dwarfs with the completed instrument. The CARMENES instrument consists of two separate echelle spectrographs covering the wavelength range from 0.55 to 1.7 μm at a spectral resolution of R = 82,000, fed by fibers from the Cassegrain focus of the telescope. The spectrographs are housed in vacuum tanks providing the temperature-stabilized environments necessary to enable a 1 m/s radial velocity precision employing a simultaneous calibration with an emission-line lamp or with a Fabry-Perot etalon. For mid-M to late-M spectral types, the wavelength range around 1.0 μm (Y band) is the most important wavelength region for radial velocity work. Therefore, the efficiency of CARMENES has been optimized in this range. The CARMENES instrument consists of two spectrographs, one equipped with a 4k x 4k pixel CCD for the range 0.55 - 1.05 μm, and one with two 2k x 2k pixel HgCdTe detectors for the range from 0.95 - 1.7μm. Each spectrograph will be coupled to the 3.5m telescope with two optical fibers, one for the target, and one for calibration light. The front end contains a dichroic beam splitter and an atmospheric dispersion corrector, to feed the light into the fibers leading to the spectrographs. Guiding is performed with a separate camera; on-axis as well as off-axis guiding modes are implemented. Fibers with octagonal cross-section are employed to ensure good stability of the output in the presence of residual guiding errors. The

  20. Calibration of "Babyline" RP instruments

    CERN Multimedia

    2015-01-01

      If you have old RP instrumentation of the “Babyline” type, as shown in the photo, please contact the Radiation Protection Group (Joffrey Germa, 73171) to have the instrument checked and calibrated. Thank you. Radiation Protection Group

  1. ZBLAN Viscosity Instrumentation

    Science.gov (United States)

    Kaukler, William

    2001-01-01

    The past year's contribution from Dr. Kaukler's experimental effort consists of these 5 parts: a) Construction and proof-of-concept testing of a novel shearing plate viscometer designed to produce small shear rates and operate at elevated temperatures; b) Preparing nonlinear polymeric materials to serve as standards of nonlinear Theological behavior; c) Measurements and evaluation of above materials for nonlinear rheometric behavior at room temperature using commercial spinning cone and plate viscometers available in the lab; d) Preparing specimens from various forms of pitch for quantitative comparative testing in a Dynamic Mechanical Analyzer, Thermal Mechanical Analyzer; and Archeological Analyzer; e) Arranging to have sets of pitch specimens tested using the various instruments listed above, from different manufacturers, to form a baseline of the viscosity variation with temperature using the different test modes offered by these instruments by compiling the data collected from the various test results. Our focus in this project is the shear thinning behavior of ZBLAN glass over a wide range of temperature. Experimentally, there are no standard techniques to perform such measurements on glasses, particularly at elevated temperatures. Literature reviews to date have shown that shear thinning in certain glasses appears to occur, but no data is available for ZBLAN glass. The best techniques to find shear thinning behavior require the application of very low rates of shear. In addition, because the onset of the thinning behavior occurs at an unknown elevated temperature, the instruments used in this study must provide controlled low rates of shear and do so for temperatures approaching 600 C. In this regard, a novel shearing parallel plate viscometer was designed and a prototype built and tested.

  2. [Automation in histology: evaluation of a device for automatic covering of histologic slides].

    Science.gov (United States)

    Lampertico, P; Gambacorta, M

    1994-02-01

    A new kind of instrument (Tissue-Tek Coverslipper) has been utilized by the Department of Surgical Pathology Cà Granda Hospital, Milano, for automatic mounting of cytohistological slides, using a pluristratified plastic film, instead of usual coverglasses. The introduction of this coverslipper has reduced the answer time, the technical work and the ambiental pollution. This coverslipper seems to be reliable, useful and very speedy; the optical quality of the slides was similar to conventional ones in our experience.

  3. RESEARCH ON EXPERT SYSTEM OF FAULT DETECTION AND DIAGNOSING FOR PNEUMATIC SYSTEM OF AUTOMATIC PRODUCTION LINE

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Fault detection and diagnosis for pneumatic system of automatic production line are studied. An expert system using fuzzy-neural network and pneumatic circuit fault diagnosis instrument are designed. The mathematical model of various pneumatic faults and experimental device are built. In the end, some experiments are done, which shows that the expert system using fuzzy-neural network can diagnose fast and truly fault of pneumatic circuit.

  4. Beam Instrument Development System

    Energy Technology Data Exchange (ETDEWEB)

    2016-01-08

    Beam Instrumentation Development System (BIDS) is a collection of common support libraries and modules developed during a series of Low-Level Radio Frequency (LLRF) control and timing/synchronization projects. BIDS includes a collection of Hardware Description Language (HDL) libraries and software libraries. The BIDS can be used for the development of any FPGA-based system, such as LLRF controllers. HDL code in this library is generic and supports common Digital Signal Processing (DSP) functions, FPGA-specific drivers (high-speed serial link wrappers, clock generation, etc.), ADC/DAC drivers, Ethernet MAC implementation, etc.

  5. Payment Instrument Characteristics

    DEFF Research Database (Denmark)

    Holst, Jacques; Kjeldsen, Martin; Hedman, Jonas;

    2015-01-01

    Over the last decade, we have witnessed payment innovations that fundamentally have changed the ways we pay. Payment innovations, such as mobile payments and on-line banking, include characteristics or features that are essential to understand if we want to know how and why payers choose among...... payment innovations. Using the Repertory Grid technique to explore 15 payers’ perception of six payment instruments, including coins, banknotes, debit cards, credit cards, mobile payments, and on-line banking, we identify 16 payment characteristics. The characteristics aggregate seventy-six unique...

  6. Payment Instrument Characteristics

    DEFF Research Database (Denmark)

    Holst, Jacques; Kjeldsen, Martin; Hedman, Jonas

    2015-01-01

    payment innovations. Using the Repertory Grid technique to explore 15 payers’ perception of six payment instruments, including coins, banknotes, debit cards, credit cards, mobile payments, and on-line banking, we identify 16 payment characteristics. The characteristics aggregate seventy-six unique......Over the last decade, we have witnessed payment innovations that fundamentally have changed the ways we pay. Payment innovations, such as mobile payments and on-line banking, include characteristics or features that are essential to understand if we want to know how and why payers choose among...

  7. 7 CFR 58.418 - Automatic cheese making equipment.

    Science.gov (United States)

    2010-01-01

    ... processing or packaging areas. (c) Automatic salter. The automatic salter shall be constructed of stainless.... The automatic salter shall be constructed so that it can be satisfactorily cleaned. The salting...

  8. Keyboard Emulation For Computerized Instrumentation

    Science.gov (United States)

    Wiegand, P. M.; Crouch, S. R.

    1989-01-01

    Keyboard emulator has interface at same level as manual keyboard entry. Since communication and control take place at high intelligence level in instrument, all instrument circuitry fully utilized. Little knowledge of instrument circuitry necessary, since only task interface performs is key closure. All existing logic and error checking still performed by instrument, minimizing workload of laboratory microcomputer. Timing constraints for interface operation minimal at keyboard entry level.

  9. Electronic Instruments -- Played or Used?

    Science.gov (United States)

    Ulveland, Randall Dana

    1998-01-01

    Compares the experience of playing an acoustic instrument to an electronic instrument by analyzing the constant structures and relationships between the experiences. Concludes that students' understanding of the physical experience of making music increases when experiences with acoustic instruments precede their exposure to electronic…

  10. Mallet Instruments Challenge Beginning Percussionists.

    Science.gov (United States)

    Grumley, Fred

    1983-01-01

    Orff mallet instruments should be used in beginning band classes. Adding mallet instruments would expand a beginner's concept of percussion instruments. Just as important, the percussion section would provide a solid melodic and harmonic foundation to assist beginning wind instrumentalists with their insecurities about pitch. (RM)

  11. Ovarian cryopreservation after laparoscopic ovariectomy using the Endo-GIA stapling device and LAPRO-clip absorbable ligating clip in a woman: a case report

    Directory of Open Access Journals (Sweden)

    Messner Alexandra

    2011-02-01

    Full Text Available Abstract Introduction Several options are available for preserving fertility before cytotoxic treatment, including ovarian tissue cryopreservation. Most reported surgical techniques include electrocoagulation. Our hypothesis is that avoidance of electrocoagulation may decrease ovarian cortex injury during cryopreservation procedures. Case presentation We report a laparoscopic technique of whole-ovary removal without coagulation using Endo-GIA forceps and clips. Laparoscopic ovariectomy was performed for cryopreservation in a 37-year-old Caucasian woman with breast cancer and for whom chemotherapy was planned. The procedure was completed quickly and without complication. This Endo-GIA procedure was of short duration with a short period of ischemia before freezing. Conclusion Laparoscopic ovariectomy using the Endo-GIA stapling device procedure without coagulation may diminish ovary injury before ovarian cryopreservation.

  12. Balances instruments, manufacturers, history

    CERN Document Server

    Robens, Erich; Kiefer, Susanne

    2014-01-01

    The book deals mainly with direct mass determination by means of a conventional balances. It covers the history of the balance from the beginnings in Egypt earlier than 3000 BC to recent developments. All balance types are described with emphasis on scientific balances. Methods of indirect mass determination, which are applied to very light objects like molecules and the basic particles of matter and celestial bodies, are included.  As additional guidance, today’s manufacturers are listed and the profile of important companies is reviewed. Several hundred photographs, reproductions and drawings show instruments and their uses. This book includes commercial weighing instruments for merchandise and raw materials in workshops as well as symbolic weighing in the ancient Egyptian’s ceremony of ‘Weighing of the Heart’, the Greek fate balance, the Roman  Justitia, Juno Moneta and Middle Ages scenes of the Last Judgement with Jesus or St. Michael and of modern balances. The photographs are selected from the...

  13. An Instrumental Innovation

    Science.gov (United States)

    1978-01-01

    Think of guitars and you think of rock and country music, or the vigorous rhythms of the gypsy flamenco, or perhaps the classical strumming of a Segovia. About the last thing you would associate with guitars is aerospace technology. Yet there is a connection. A whole family of quality guitars is an outgrowth of helicopter rotor research conducted for the military services and NASA by an aerospace contractor. These musical spinoffs, commercially available and rapidly gaining in popularity, are the Ovation guitar line, manufactured by Ovation Instruments, Inc., Bloomfield, Connecticut. Ovation Instruments is a subsidiary of Kaman Corporation, a diversified company originally formed to develop and build helicopters. A helicopter's rotor system, with thousands of moving parts, is highly susceptible to vibration. For rotor efficiency, vibration must be "dampened," or reduced. Like other helicopter builders, Kaman Corporation spent years of research toward that end. The technology thus developed, together with the availability of staff experts in vibration engineering, sparked an idea in the mind of the company's president and founder, Charles H. Karnan. A guitarist of professional caliber, Kaman reasoned that vibration-dampening technology could be turned around to enhance vibration and thereby produce a guitar with superior sound.

  14. The QUIET Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, C.; et al.

    2012-07-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ({approx}1{sup o}). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0:1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0:01. The two arrays together cover multipoles in the range {ell} {approx} 25 -- 975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument.

  15. A Hierarchy of Tree-Automatic Structures

    CERN Document Server

    Finkel, Olivier

    2011-01-01

    We consider $\\omega^n$-automatic structures which are relational structures whose domain and relations are accepted by automata reading ordinal words of length $\\omega^n$ for some integer $n\\geq 1$. We show that all these structures are $\\omega$-tree-automatic structures presentable by Muller or Rabin tree automata. We prove that the isomorphism relation for $\\omega^2$-automatic (resp. $\\omega^n$-automatic for $n>2$) boolean algebras (respectively, partial orders, rings, commutative rings, non commutative rings, non commutative groups) is not determined by the axiomatic system ZFC. We infer from the proof of the above result that the isomorphism problem for $\\omega^n$-automatic boolean algebras, $n > 1$, (respectively, rings, commutative rings, non commutative rings, non commutative groups) is neither a $\\Sigma_2^1$-set nor a $\\Pi_2^1$-set. We obtain that there exist infinitely many $\\omega^n$-automatic, hence also $\\omega$-tree-automatic, atomless boolean algebras $B_n$, $n\\geq 1$, which are pairwise isomorp...

  16. Comparing Automatic CME Detections in Multiple LASCO and SECCHI Catalogs

    Science.gov (United States)

    Hess, Phillip; Colaninno, Robin C.

    2017-02-01

    With the creation of numerous automatic detection algorithms, a number of different catalogs of coronal mass ejections (CMEs) spanning the entirety of the Solar and Heliospheric Observatory (SOHO) Large Angle Spectrometric Coronagraph (LASCO) mission have been created. Some of these catalogs have been further expanded for use on data from the Solar Terrestrial Earth Observatory (STEREO) Sun Earth Connection Coronal and Heliospheric Investigation (SECCHI) as well. We compare the results from different automatic detection catalogs (Solar Eruption Event Detection System (SEEDS), Computer Aided CME Tracking (CACTus), and Coronal Image Processing (CORIMP)) to ensure the consistency of detections in each. Over the entire span of the LASCO catalogs, the automatic catalogs are well correlated with one another, to a level greater than 0.88. Focusing on just periods of higher activity, these correlations remain above 0.7. We establish the difficulty in comparing detections over the course of LASCO observations due to the change in the instrument image cadence in 2010. Without adjusting catalogs for the cadence, CME detection rates show a large spike in cycle 24, despite a notable drop in other indices of solar activity. The output from SEEDS, using a consistent image cadence, shows that the CME rate has not significantly changed relative to sunspot number in cycle 24. These data, and mass calculations from CORIMP, lead us to conclude that any apparent increase in CME rate is a result of the change in cadence. We study detection characteristics of CMEs, discussing potential physical changes in events between cycles 23 and 24. We establish that, for detected CMEs, physical parameters can also be sensitive to the cadence.

  17. What K-12 Teachers of Earth Science Need from the Earth Science Research Community: Science Teaching and Professional Learning in the Earth Sciences (STAPLES), a Minnesota Case Study

    Science.gov (United States)

    Campbell, K. M.; Pound, K. S.; Rosok, K.; Baumtrog, J.

    2009-12-01

    NSF-style Broader Impacts activities in the Earth Sciences take many forms, from long term partnerships between universities and informal science institutions to one-time K-12 classroom visits by scientists. Broader Impacts that include K-12 teachers range from those that convey broad Earth Science concepts to others stressing direct connections to very specific current research methods and results. Design of these programs is often informed by prior successful models and a broad understanding of teacher needs, but is not specifically designed to address needs expressed by teachers themselves. In order to better understand teachers’ perceived needs for connections to Earth Science research, we have formed the Science Teaching and Professional Learning in the Earth Sciences (STAPLES) research team. Our team includes a geology faculty member experienced in undergraduate and professional Earth Science teacher training, two in-service middle school Earth Science teachers, and the Education Director of the National Center for Earth-surface Dynamics (NCED), a National Science Foundation Science and Technology Center. Members of the team have designed, taught and experienced many of these models, from the Andrill ARISE program to NCED’s summer institutes and teacher internship program. We are administering the STAPLES survey to ask Earth Science teachers in our own state (Minnesota) which of many models they use to 1) strengthen their own understanding of current Earth Science research and general Earth Science concepts and 2) deepen their students’ understanding of Earth Science content. Our goal is to share survey results to inform more effective Broader Impacts programs in Minnesota and to stimulate a wider national discussion of effective Broader Impacts programs that includes teachers’ voices.

  18. Spinning process of 2.22 dtex polyphenylene sulfide staple fiber%2.22 dtex聚苯硫醚短纤维纺丝工艺的探讨

    Institute of Scientific and Technical Information of China (English)

    刘先正; 李艳玲; 刘秀清; 成郁君

    2013-01-01

    采用含水率小于50 μg/g的聚苯硫醚(PPS)切片熔融纺丝生产PPS短纤维,对纺丝工艺条件进行了探讨.结果表明:控制PPS切片干燥温度120~140℃,干燥时间8~10 h,纺丝温度330℃,环吹风温度23 ~26℃,环吹风速度1.3 ~1.6 m/s,拉伸槽温度90 ~100℃,紧张热定型温度150~180℃,单体抽吸速度0.4 s/min,总拉伸倍数3.4 ~4.4,纺丝过程平稳,生产2.22 dtex PPS短纤维断裂强度大于等于4.2 cN/dtex,断裂伸长率为34.2%.%Polyphenylene sulfide (PPS) staple fiber was prepared from PPS chip with moisture content less than 50μg/g by melt spinning process. The spinning process conditions were discussed. The results showed that the 2. 22 dtex PPS staple fiber can be steadily produced with the breaking strength not less than 4.2 cN/dtex and elongation at break of 34.2% under the conditions as followed: PPS chip drying temperature 120 - 140℃, drying time 8 - 10 h, spinning temperature 330℃, circular air blow temperature 23-26℃ and speed 1.3-1.6 m/s, drafting groove temperature 90 - 100℃, heat setting temperature under tension 150 - 180℃ , monomer suction speed 0.4 s/min, total draw ratio 3.4 -4.4.

  19. Sterilization of Staple Foods in Retort Pouch%软包装主食罐头杀菌工艺研究

    Institute of Scientific and Technical Information of China (English)

    郑志强; 刘嘉喜; 王越鹏

    2012-01-01

    对软包装主食罐头的杀菌工艺进行研究,分析在不同杀菌温度和时间条件下食品中心温度及F值的变化,确定最佳杀菌方式为双峰高温杀菌,杀菌参数为80℃、5min,110℃、5min,121℃、12min,125℃、(30+30)s,峰底113℃,该杀菌工艺能够有效降低软包装主食罐头的杀菌强度,杀菌后的产品大大降低了因高温产生的后熟蒸馏味,大幅延长了保质期,最终产品品质显著提高。%This study was undertaken to investigate the sterilization of retort pouches containing staple foods.Variations in central temperature and F value were analyzed under various conditions of sterilization temperature and time.The optimal sterilization process was double peak high temperature sterilization at 80 ℃ for 5 min,110 ℃ for 5 min,121 ℃ for 12 min and 125 ℃ for 30 s + 30 s with a peak base temperature of 113 ℃.Under these conditions,the sterilization intensity of retort pouches was attenuated effectively.Moreover,the distillation odor caused by high-temperature sterilization was reduced greatly,and the shelf life was markedly extended.As a result,the quality of staple foods could be obviously improved.

  20. Pattern-Driven Automatic Parallelization

    Directory of Open Access Journals (Sweden)

    Christoph W. Kessler

    1996-01-01

    Full Text Available This article describes a knowledge-based system for automatic parallelization of a wide class of sequential numerical codes operating on vectors and dense matrices, and for execution on distributed memory message-passing multiprocessors. Its main feature is a fast and powerful pattern recognition tool that locally identifies frequently occurring computations and programming concepts in the source code. This tool also works for dusty deck codes that have been "encrypted" by former machine-specific code transformations. Successful pattern recognition guides sophisticated code transformations including local algorithm replacement such that the parallelized code need not emerge from the sequential program structure by just parallelizing the loops. It allows access to an expert's knowledge on useful parallel algorithms, available machine-specific library routines, and powerful program transformations. The partially restored program semantics also supports local array alignment, distribution, and redistribution, and allows for faster and more exact prediction of the performance of the parallelized target code than is usually possible.

  1. Automatic image cropping for republishing

    Science.gov (United States)

    Cheatle, Phil

    2010-02-01

    Image cropping is an important aspect of creating aesthetically pleasing web pages and repurposing content for different web or printed output layouts. Cropping provides both the possibility of improving the composition of the image, and also the ability to change the aspect ratio of the image to suit the layout design needs of different document or web page formats. This paper presents a method for aesthetically cropping images on the basis of their content. Underlying the approach is a novel segmentation-based saliency method which identifies some regions as "distractions", as an alternative to the conventional "foreground" and "background" classifications. Distractions are a particular problem with typical consumer photos found on social networking websites such as FaceBook, Flickr etc. Automatic cropping is achieved by identifying the main subject area of the image and then using an optimization search to expand this to form an aesthetically pleasing crop. Evaluation of aesthetic functions like auto-crop is difficult as there is no single correct solution. A further contribution of this paper is an automated evaluation method which goes some way towards handling the complexity of aesthetic assessment. This allows crop algorithms to be easily evaluated against a large test set.

  2. Automatic segmentation of psoriasis lesions

    Science.gov (United States)

    Ning, Yang; Shi, Chenbo; Wang, Li; Shu, Chang

    2014-10-01

    The automatic segmentation of psoriatic lesions is widely researched these years. It is an important step in Computer-aid methods of calculating PASI for estimation of lesions. Currently those algorithms can only handle single erythema or only deal with scaling segmentation. In practice, scaling and erythema are often mixed together. In order to get the segmentation of lesions area - this paper proposes an algorithm based on Random forests with color and texture features. The algorithm has three steps. The first step, the polarized light is applied based on the skin's Tyndall-effect in the imaging to eliminate the reflection and Lab color space are used for fitting the human perception. The second step, sliding window and its sub windows are used to get textural feature and color feature. In this step, a feature of image roughness has been defined, so that scaling can be easily separated from normal skin. In the end, Random forests will be used to ensure the generalization ability of the algorithm. This algorithm can give reliable segmentation results even the image has different lighting conditions, skin types. In the data set offered by Union Hospital, more than 90% images can be segmented accurately.

  3. Automatic Assessment of Programming assignment

    Directory of Open Access Journals (Sweden)

    Surendra Gupta

    2012-01-01

    Full Text Available In today’s world study of computer’s language is more important. Effective and good programming skills are need full all computer science students. They can be master in programming, only through intensive exercise practices. Due to day by day increasing number of students in the class, the assessment of programming exercises leads to extensive workload for teacher/instructor, particularly if it has to be carried out manually. In this paper, we propose an automatic assessment system for programming assignments, using verification program with random inputs. One of the most important properties of a program is that, it carries out its intended function. The intended function of a program or part of a program can be verified by using inverse function’s verification program. For checking intended functionality and evaluation of a program, we have used verification program. This assessment system has been tested on basic C programming courses, and results shows that it can work well in basic programming exercises, with some initial promising results

  4. Real-time 3D visual tracking of laparoscopic instruments for robotized endoscope holder.

    Science.gov (United States)

    Zhao, Zijian

    2014-01-01

    Robotized endoscope holder in laparoscopic surgeries allows surgeons to control the endoscope without the assistants' intervention. In this paper, a new method is proposed for the automatic 3D-tracking of laparoscopic instruments in real-time to provide more convenient interactions between surgeons and the robotized endoscope holder. The method is based on the 3D position measurements of the insertion points of the instruments and the strip markers, combined with the depth estimation of the instruments. The results of our experiments show that our method is fast and robust in the simulated laparoscopic surgeries.

  5. Automatic Testing of a CANopen Node

    OpenAIRE

    Liang, Hui

    2013-01-01

    This Bachelor’s thesis was commissioned by TK Engineering Oy in Vaasa. The goals of the thesis were to test a prototype CANopen node, called UWASA Node for conformance to the CiA 301 standard, and to develop the automatic performance test software and the automatic CiA 401 test software. A test report that describes to the designer what needs to be corrected and improved is made in this thesis. For the CiA 301 test there is a CANopen conformance test tool that can be used. The automatic perfo...

  6. An Automatic Clustering Technique for Optimal Clusters

    CERN Document Server

    Pavan, K Karteeka; Rao, A V Dattatreya; 10.5121/ijcsea.2011.1412

    2011-01-01

    This paper proposes a simple, automatic and efficient clustering algorithm, namely, Automatic Merging for Optimal Clusters (AMOC) which aims to generate nearly optimal clusters for the given datasets automatically. The AMOC is an extension to standard k-means with a two phase iterative procedure combining certain validation techniques in order to find optimal clusters with automation of merging of clusters. Experiments on both synthetic and real data have proved that the proposed algorithm finds nearly optimal clustering structures in terms of number of clusters, compactness and separation.

  7. Astronomical Instrumentation System Markup Language

    Science.gov (United States)

    Goldbaum, Jesse M.

    2016-05-01

    The Astronomical Instrumentation System Markup Language (AISML) is an Extensible Markup Language (XML) based file format for maintaining and exchanging information about astronomical instrumentation. The factors behind the need for an AISML are first discussed followed by the reasons why XML was chosen as the format. Next it's shown how XML also provides the framework for a more precise definition of an astronomical instrument and how these instruments can be combined to form an Astronomical Instrumentation System (AIS). AISML files for several instruments as well as one for a sample AIS are provided. The files demonstrate how AISML can be utilized for various tasks from web page generation and programming interface to instrument maintenance and quality management. The advantages of widespread adoption of AISML are discussed.

  8. The MICE PID Instrumentation

    CERN Document Server

    Bonesini, M

    2008-01-01

    The international Muon Ionization Cooling Experiment (MICE) will carry out a systematic investigation of ionization cooling of a muon beam. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation is needed to measure particle coordinates and timing vs RF. A PID system based on three time-of-flight stations, two Aerogel Cerenkov detectors and a KLOE-like calorimeter has been constructed in order to keep beam contamination ($e, \\pi$) well below 1%. The MICE time-of-flight system will measure timing with a resolution better than 70 ps per plane, in a harsh environment due to high particle rates, fringe magnetic fields and electron backgrounds from RF dark current.

  9. Reconfigurable laser ranging instrument

    Science.gov (United States)

    Schneiter, John

    1994-03-01

    This paper describes the design and operation of a fast, flexible, non-contact, eye-safe laser ranging instrument useful in a variety of industrial metrology situations, such as in-process machining control and part inspection. The system has variable computer-controlled standoff and depth of field, and can obtain 3-D images of surfaces within a range of from 1.5 ft to almost 10 ft from the final optical element. The minimum depth of field is about 3.5 in. at 1.5 ft and about 26 in. at the far range. The largest depth of field for which useful data are available is about 41 in. Resolution, with appropriate averaging, is about one part in 4000 of the depth of field, which implies a best case resolution for this prototype of 0.00075 in. System flexibility is achieved by computer controlled relative positioning of optical components.

  10. Portable musical instrument amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Christian, David E. (Danbury, CT)

    1990-07-24

    The present invention relates to a musical instrument amplifier which is particularly useful for electric guitars. The amplifier has a rigid body for housing both the electronic system for amplifying and processing signals from the guitar and the system's power supply. An input plug connected to and projecting from the body is electrically coupled to the signal amplifying and processing system. When the plug is inserted into an output jack for an electric guitar, the body is rigidly carried by the guitar, and the guitar is operatively connected to the electrical amplifying and signal processing system without use of a loose interconnection cable. The amplifier is provided with an output jack, into which headphones are plugged to receive amplified signals from the guitar. By eliminating the conventional interconnection cable, the amplifier of the present invention can be used by musicians with increased flexibility and greater freedom of movement.

  11. Instrumented Pipeline Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Piro; Michael Ream

    2010-07-31

    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.

  12. Aprendizaje instrumental en anfibios

    Directory of Open Access Journals (Sweden)

    Rubén N. Muzio

    1999-01-01

    Full Text Available Este trabajo presenta una revisión de los estudios realizados acerca de los mecanismos de aprendizaje en anfibios. Se conoce muy poco acerca de los procesos de aprendizaje en anfibios, y aún menos respecto de las relaciones cerebro-aprendizaje. Recientemente hemos comenzado el estudio sistemático del aprendizaje instrumental en el sapo Bufo arenarum dentro de un marco comparativo. Se observaron diversos fenómenos de aprendizaje comunes a una amplia variedad de vertebrados, tales como la adquisición bajo condiciones de entrenamiento masivo y espaciado, la extinción, la recuperación espontánea, el efecto subsiguiente al refuerzo, y el efecto en al adquisición de la magnitud del reforzamiento. Además, comenzamos el análisis de los efectos sobre el aprendizaje de las lesiones del pallium medial (estructura postulada como homóloga al hipocampo de los mamíferos. La lesión del paIlium medial no tuvo efectos sobre el desempeño ni sobre la tasa de captación de agua durante la adquisición. Pero retardó significativamente la extinción de la respuesta instrumental en un corredor recto. Estos datos sugieren que el palli um medial de los sapos juega un papel en la inhibición de respuestas previamente aprendidas. Los resultados de nuestros estudios en el sapo Bufo arenarum aportan datos origi na1es a la limitada información disponible sobre aprendizaje en anfibios.

  13. 12th Portuguese Conference on Automatic Control

    CERN Document Server

    Soares, Filomena; Moreira, António

    2017-01-01

    The biennial CONTROLO conferences are the main events promoted by The CONTROLO 2016 – 12th Portuguese Conference on Automatic Control, Guimarães, Portugal, September 14th to 16th, was organized by Algoritmi, School of Engineering, University of Minho, in partnership with INESC TEC, and promoted by the Portuguese Association for Automatic Control – APCA, national member organization of the International Federation of Automatic Control – IFAC. The seventy-five papers published in this volume cover a wide range of topics. Thirty-one of them, of a more theoretical nature, are distributed among the first five parts: Control Theory; Optimal and Predictive Control; Fuzzy, Neural and Genetic Control; Modeling and Identification; Sensing and Estimation. The papers go from cutting-edge theoretical research to innovative control applications and show expressively how Automatic Control can be used to increase the well being of people. .

  14. Automaticity in social-cognitive processes.

    Science.gov (United States)

    Bargh, John A; Schwader, Kay L; Hailey, Sarah E; Dyer, Rebecca L; Boothby, Erica J

    2012-12-01

    Over the past several years, the concept of automaticity of higher cognitive processes has permeated nearly all domains of psychological research. In this review, we highlight insights arising from studies in decision-making, moral judgments, close relationships, emotional processes, face perception and social judgment, motivation and goal pursuit, conformity and behavioral contagion, embodied cognition, and the emergence of higher-level automatic processes in early childhood. Taken together, recent work in these domains demonstrates that automaticity does not result exclusively from a process of skill acquisition (in which a process always begins as a conscious and deliberate one, becoming capable of automatic operation only with frequent use) - there are evolved substrates and early childhood learning mechanisms involved as well.

  15. Automatic lexical classification: bridging research and practice.

    Science.gov (United States)

    Korhonen, Anna

    2010-08-13

    Natural language processing (NLP)--the automatic analysis, understanding and generation of human language by computers--is vitally dependent on accurate knowledge about words. Because words change their behaviour between text types, domains and sub-languages, a fully accurate static lexical resource (e.g. a dictionary, word classification) is unattainable. Researchers are now developing techniques that could be used to automatically acquire or update lexical resources from textual data. If successful, the automatic approach could considerably enhance the accuracy and portability of language technologies, such as machine translation, text mining and summarization. This paper reviews the recent and on-going research in automatic lexical acquisition. Focusing on lexical classification, it discusses the many challenges that still need to be met before the approach can benefit NLP on a large scale.

  16. Automatic identification for standing tree limb pruning

    Institute of Scientific and Technical Information of China (English)

    Sun Renshan; Li Wenbin; Tian Yongchen; Hua Li

    2006-01-01

    To meet the demand of automatic pruning machines,this paper presents a new method for dynamic automatic identification of standing tree limbs and capture of the digital images of Platycladus orientalis.Methods of computer vision,image processing and wavelet analysis technology were used to compress,filter,segment,abate noise and capture the outline of the picture.We then present the arithmetic for dynamic automatic identification of standing tree limbs,extracting basic growth characteristics of the standing trees such as the form,size,degree of bending and their relative spatial position.We use pattern recognition technology to confirm the proportionate relationship matching the database and thus achieve the goal of dynamic automatic identification of standing tree limbs.

  17. A Demonstration of Automatically Switched Optical Network

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    We build an automatically switched optical network (ASON) testbed with four optical cross-connect nodes. Many fundamental ASON features are demonstrated, which is implemented by control protocols based on generalized multi-protocol label switching (GMPLS) framework.

  18. Automatic acquisition of pattern collocations in GO

    Institute of Scientific and Technical Information of China (English)

    LIU Zhi-qing; DOU Qing; LI Wen-hong; LU Ben-jie

    2008-01-01

    The quality, quantity, and consistency of the knowledgeused in GO-playing programs often determine their strengths,and automatic acquisition of large amounts of high-quality andconsistent GO knowledge is crucial for successful GO playing.In a previous article of this subject, we have presented analgorithm for efficient and automatic acquisition of spatialpatterns of GO as well as their frequency of occurrence fromgame records. In this article, we present two algorithms, one forefficient and automatic acquisition of pairs of spatial patternsthat appear jointly in a local context, and the other for deter-mining whether the joint pattern appearances are of certainsignificance statistically and not just a coincidence. Results ofthe two algorithms include 1 779 966 pairs of spatial patternsacquired automatically from 16 067 game records of profess-sional GO players, of which about 99.8% are qualified as patterncollocations with a statistical confidence of 99.5% or higher.

  19. 2014 United States Automatic Identification System Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 2014 United States Automatic Identification System Database contains vessel traffic data for planning purposes within the U.S. coastal waters. The database is...

  20. Automatization and familiarity in repeated checking

    NARCIS (Netherlands)

    Dek, Eliane C P; van den Hout, Marcel A.; Giele, Catharina L.; Engelhard, Iris M.

    2014-01-01

    Repeated checking paradoxically increases memory uncertainty. This study investigated the underlying mechanism of this effect. We hypothesized that as a result of repeated checking, familiarity with stimuli increases, and automatization of the checking procedure occurs, which should result in decrea

  1. Automatic Speech Segmentation Based on HMM

    Directory of Open Access Journals (Sweden)

    M. Kroul

    2007-06-01

    Full Text Available This contribution deals with the problem of automatic phoneme segmentation using HMMs. Automatization of speech segmentation task is important for applications, where large amount of data is needed to process, so manual segmentation is out of the question. In this paper we focus on automatic segmentation of recordings, which will be used for triphone synthesis unit database creation. For speech synthesis, the speech unit quality is a crucial aspect, so the maximal accuracy in segmentation is needed here. In this work, different kinds of HMMs with various parameters have been trained and their usefulness for automatic segmentation is discussed. At the end of this work, some segmentation accuracy tests of all models are presented.

  2. Automatic coding of online collaboration protocols

    NARCIS (Netherlands)

    Erkens, Gijsbert; Janssen, J.J.H.M.

    2006-01-01

    An automatic coding procedure is described to determine the communicative functions of messages in chat discussions. Five main communicative functions are distinguished: argumentative (indicating a line of argumentation or reasoning), responsive (e.g., confirmations, denials, and answers), informati

  3. 2010 United States Automatic Identification System Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 2010 United States Automatic Identification System Database contains vessel traffic data for planning purposes within the U.S. coastal waters. The database is...

  4. Collapsible truss structure is automatically expandable

    Science.gov (United States)

    1965-01-01

    Coil springs wound with maximum initial tension in a three-truss, closed loop structure form a collapsible truss structure. The truss automatically expands and provides excellent rigidity and close dimensional tolerance when expanded.

  5. Tool – Material, Metaphor – Metonymy, Instrument(ness)

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege; Breinbjerg, Morten; Pold, Søren

    2008-01-01

    This paper, presents in an abbreviated form the argument presented in an earlier paper[1], and tries to relate it to the theme, "retro in the interface". We introduce the concept instrumentness as a quality of human-computer interfaces. Instrumentness points to the way musical instruments are con...... pointing to alternative values, differing from traditional usability, which are also relevant in creative work outside art and music composition.......This paper, presents in an abbreviated form the argument presented in an earlier paper[1], and tries to relate it to the theme, "retro in the interface". We introduce the concept instrumentness as a quality of human-computer interfaces. Instrumentness points to the way musical instruments...... are controlled and conceptualized through values such as virtuosity and palyability, which are important for computer-mediated creative work supporting development in use beyond what is initially designed for. The papet performs a conceptual investigation into qualities in software interfaces that support...

  6. Incidence of instrument separation using LightSpeed rotary instruments.

    Science.gov (United States)

    Knowles, Kenneth I; Hammond, Nathan B; Biggs, Stephen G; Ibarrola, Jose L

    2006-01-01

    The use of nickel-titanium rotary instrument systems has gained popularity over the past 10 years. One of these instrument systems is the LightSpeed (LightSpeed Technology, Inc, San Antonio, TX). One drawback for all nickel-titanium rotary instruments is the incidence of instrument separation. The purpose of this study was to evaluate the incidence of nonretrievable instrument separation using the LightSpeed system in a clinical setting. A total of 3543 canals were treated over a 24 month period and during that time, 46 LightSpeed instruments were separated and found to be nonretrievable, resulting in a separation rate of 1.30%. This rate was lower than previous reported studies.

  7. An intelligent instrument for measuring exhaust temperature of marine engine

    Institute of Scientific and Technical Information of China (English)

    MA Nan-qi; SU Hua; LIU Jun

    2006-01-01

    Exhaust temperature of the marine engine is commonly measured through thermocouple.Measure deviation will occur after using the thermocouple for some time due to nonlinearity of thermocouple itself, high temperature and chemical corrosion of measure point. Frequent replacement of thermocouple will increase the operating cost. This paper designs a new intelligent instrument for solving the above-mentioned problems of the marine engine temperature measurement, which combines the conventional thermocouple temperature measurement technology and SCM(single chip microcomputer).The reading of the thermocouple is simple and precise and the calibration can be made automatically and manually..

  8. Commissioning and First Performance of the LHC Beam Instrumentation

    CERN Document Server

    Jones, O R

    2010-01-01

    This paper will outline the progress with LHC commissioning to date, detailing the performance achieved with all the main LHC beam instrumentation systems. It will include an overview of the beam loss system and its role in machine protection, along with that of the beam position system and its use for automatic orbit control. Results will be shown from the highly sensitive base band tune system as well as the bunch-bybunch and DC beam current transformer systems, the synchrotron light monitoring systems, the wire scanner system and OTR screens.

  9. Phoneme vs Grapheme Based Automatic Speech Recognition

    OpenAIRE

    Magimai.-Doss, Mathew; Dines, John; Bourlard, Hervé; Hermansky, Hynek

    2004-01-01

    In recent literature, different approaches have been proposed to use graphemes as subword units with implicit source of phoneme information for automatic speech recognition. The major advantage of using graphemes as subword units is that the definition of lexicon is easy. In previous studies, results comparable to phoneme-based automatic speech recognition systems have been reported using context-independent graphemes or context-dependent graphemes with decision trees. In this paper, we study...

  10. Automatic quiz generation for elderly people

    OpenAIRE

    Samuelsen, Jeanette

    2016-01-01

    Studies have indicated that games can be beneficial for the elderly, in areas such as cognitive functioning and well-being. Taking part in social activities, such as playing a game with others, could also be beneficial. One type of game is a computer-based quiz. One can create quiz questions manually; however, this can be time-consuming. Another approach is to generate quiz questions automatically. This project has examined how quizzes for Norwegian elderly can be automatically generated usin...

  11. Automatic Age Estimation System for Face Images

    OpenAIRE

    Chin-Teng Lin; Dong-Lin Li; Jian-Hao Lai; Ming-Feng Han; Jyh-Yeong Chang

    2012-01-01

    Humans are the most important tracking objects in surveillance systems. However, human tracking is not enough to provide the required information for personalized recognition. In this paper, we present a novel and reliable framework for automatic age estimation based on computer vision. It exploits global face features based on the combination of Gabor wavelets and orthogonal locality preserving projections. In addition, the proposed system can extract face aging features automatically in rea...

  12. Automatic Control of Freeboard and Turbine Operation

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter; Frigaard, Peter Bak; Friis-Madsen, Erik;

    The report deals with the modules for automatic control of freeboard and turbine operation on board the Wave dragon, Nissum Bredning (WD-NB) prototype, and covers what has been going on up to ultimo 2003.......The report deals with the modules for automatic control of freeboard and turbine operation on board the Wave dragon, Nissum Bredning (WD-NB) prototype, and covers what has been going on up to ultimo 2003....

  13. Automatic terrain modeling using transfinite element analysis

    KAUST Repository

    Collier, Nathaniel O.

    2010-05-31

    An automatic procedure for modeling terrain is developed based on L2 projection-based interpolation of discrete terrain data onto transfinite function spaces. The function space is refined automatically by the use of image processing techniques to detect regions of high error and the flexibility of the transfinite interpolation to add degrees of freedom to these areas. Examples are shown of a section of the Palo Duro Canyon in northern Texas.

  14. Automatic Fringe Detection Of Dynamic Moire Patterns

    Science.gov (United States)

    Fang, Jing; Su, Xian-ji; Shi, Hong-ming

    1989-10-01

    Fringe-carrier method is used in automatic fringe-order numbering of dynamic in-plane moire patterns. In experiment both static carrier and dynamic moire patterns are recorded. The image files corresponding to instants are set up to assign fringe orders automatically. Subtracting the carrier image from the modulated ones, the moire patterns due to the dynamic deformations are restored with fringe-order variation displayed by different grey levels.

  15. Automatic safety rod for reactors. [LMFBR

    Science.gov (United States)

    Germer, J.H.

    1982-03-23

    An automatic safety rod for a nuclear reactor containing neutron absorbing material and designed to be inserted into a reactor core after a loss-of-flow. Actuation is based upon either a sudden decrease in core pressure drop or the pressure drop decreases below a predetermined minimum value. The automatic control rod includes a pressure regulating device whereby a controlled decrease in operating pressure due to reduced coolant flow does not cause the rod to drop into the core.

  16. Automatic penalty continuation in structural topology optimization

    DEFF Research Database (Denmark)

    Rojas Labanda, Susana; Stolpe, Mathias

    2015-01-01

    this issue is addressed. We propose an automatic continuation method, where the material penalization parameter is included as a new variable in the problem and a constraint guarantees that the requested penalty is eventually reached. The numerical results suggest that this approach is an appealing...... alternative to continuation methods. Automatic continuation also generally obtains better designs than the classical formulation using a reduced number of iterations....

  17. UMLS-based automatic image indexing.

    Science.gov (United States)

    Sneiderman, C; Sneiderman, Charles Alan; Demner-Fushman, D; Demner-Fushman, Dina; Fung, K W; Fung, Kin Wah; Bray, B; Bray, Bruce

    2008-01-01

    To date, most accurate image retrieval techniques rely on textual descriptions of images. Our goal is to automatically generate indexing terms for an image extracted from a biomedical article by identifying Unified Medical Language System (UMLS) concepts in image caption and its discussion in the text. In a pilot evaluation of the suggested image indexing method by five physicians, a third of the automatically identified index terms were found suitable for indexing.

  18. Ex-core instrumentation; Instrumentation hors coeur des reacteurs

    Energy Technology Data Exchange (ETDEWEB)

    Burel, J.P. [Schneider Electric S.A., 92 - Boulogne-Billancourt (France)

    1999-01-01

    The safety and the control of the reactor need to master the nuclear power from the core radiation measurement. According to the reactor dimensions and conception, the nuclear parameters monitoring is realized through two instrumentation systems: the ex-core instrumentation system which use detector placed outside of the core and the in-core instrumentation system. This paper deals with the ex-core systems based on neutronic measurements and details the detectors choice, the treatment circuits, data processing, realizations in France and also example of the Wwr reactor instrumentation. (A.L.B.)

  19. Pancreatitis Quality of Life Instrument: Development of a new instrument

    Directory of Open Access Journals (Sweden)

    Wahid Wassef

    2014-02-01

    Full Text Available Objectives: The goal of this project was to develop the first disease-specific instrument for the evaluation of quality of life in chronic pancreatitis. Methods: Focus groups and interview sessions were conducted, with chronic pancreatitis patients, to identify items felt to impact quality of life which were subsequently formatted into a paper-and-pencil instrument. This instrument was used to conduct an online survey by an expert panel of pancreatologists to evaluate its content validity. Finally, the modified instrument was presented to patients during precognitive testing interviews to evaluate its clarity and appropriateness. Results: In total, 10 patients were enrolled in the focus groups and interview sessions where they identified 50 items. Once redundant items were removed, the 40 remaining items were made into a paper-and-pencil instrument referred to as the Pancreatitis Quality of Life Instrument. Through the processes of content validation and precognitive testing, the number of items in the instrument was reduced to 24. Conclusions: This marks the development of the first disease-specific instrument to evaluate quality of life in chronic pancreatitis. It includes unique features not found in generic instruments (economic factors, stigma, and spiritual factors. Although this marks a giant step forward, psychometric evaluation is still needed prior to its clinical use.

  20. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R

    2000-01-01

    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...