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Sample records for auricular por cochliomyia

  1. Molecular phylogeny of the forensically important genus Cochliomyia (Diptera: Calliphoridae).

    Science.gov (United States)

    Yusseff-Vanegas, Sohath; Agnarsson, Ingi

    2016-01-01

    Cochliomyia Townsend includes several abundant and one of the most broadly distributed, blow flies in the Americas, and is of significant economic and forensic importance. For decades, Cochliomyia hominivorax (Coquerel) and Cochliomyia macellaria (Fabricius) have received attention as livestock parasites and primary indicator species in forensic entomology. However, Cochliomyia minima Shannon and Cochliomyia aldrichi Del Ponte have only been subject to basic taxonomy and faunistic studies. Here we present the first complete phylogeny of Cochliomyia including numerous specimens per species, collected from 13 localities in the Caribbean. Four genes, the mitochondrial COI and the nuclear EF-1α, 28S rRNA, and ITS2, were analyzed. While we found some differences among gene trees, a concatenated gene matrix recovered a robustly supported monophyletic Cochliomyia with Compsomyiops Townsend as its sister group and recovered the monophyly of Cochliomyia hominivorax, Cochliomyia macellaria and Cochliomyia minima. Our results support a close relationship between Cochliomyia minima and Cochliomyia aldrichi. However, we found Cochliomyia aldrichi containing Cochliomyia minima, indicating recent speciation, or issues with the taxonomy of the group. We provide basic information on habitat preference, distribution and feeding habits of Cochliomyia minima and Cochliomyia aldrichi that will be useful for future forensic studies in the Caribbean. PMID:27563274

  2. Molecular phylogeny of the forensically important genus Cochliomyia (Diptera: Calliphoridae)

    Science.gov (United States)

    Yusseff-Vanegas, Sohath; Agnarsson, Ingi

    2016-01-01

    Abstract Cochliomyia Townsend includes several abundant and one of the most broadly distributed, blow flies in the Americas, and is of significant economic and forensic importance. For decades, Cochliomyia hominivorax (Coquerel) and Cochliomyia macellaria (Fabricius) have received attention as livestock parasites and primary indicator species in forensic entomology. However, Cochliomyia minima Shannon and Cochliomyia aldrichi Del Ponte have only been subject to basic taxonomy and faunistic studies. Here we present the first complete phylogeny of Cochliomyia including numerous specimens per species, collected from 13 localities in the Caribbean. Four genes, the mitochondrial COI and the nuclear EF-1α, 28S rRNA, and ITS2, were analyzed. While we found some differences among gene trees, a concatenated gene matrix recovered a robustly supported monophyletic Cochliomyia with Compsomyiops Townsend as its sister group and recovered the monophyly of Cochliomyia hominivorax, Cochliomyia macellaria and Cochliomyia minima. Our results support a close relationship between Cochliomyia minima and Cochliomyia aldrichi. However, we found Cochliomyia aldrichi containing Cochliomyia minima, indicating recent speciation, or issues with the taxonomy of the group. We provide basic information on habitat preference, distribution and feeding habits of Cochliomyia minima and Cochliomyia aldrichi that will be useful for future forensic studies in the Caribbean. PMID:27563274

  3. Auricular Acupuncture with Laser

    OpenAIRE

    Regina Round; Gerhard Litscher; Frank Bahr

    2013-01-01

    Auricular acupuncture is a method which has been successfully used in various fields of medicine especially in the treatment of pain relief. The introduction of lasers especially low-level lasers into medicine brought besides the already existing stimulation with needles and electricity an additional technique to auricular acupuncture. This literature research looks at the historical background, the development and the anatomical and neurological aspects of auricular acupuncture in general an...

  4. Development and utilization of transgenic New World screwworm, Cochliomyia hominivorax

    Science.gov (United States)

    The New World Screwworm (NWS), Cochliomyia hominivorax, was the first insect to be effectively controlled using the sterile insect technique (SIT). Recent efforts to improve NWS SIT biological control have centered on the development of genetically transformed strains using the piggyBac transposon...

  5. Auricular chromoblastomycosis: case report Cromoblastomicose auricular: relato de um caso

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    Achiléa Lisboa Bittencourt

    1994-08-01

    Full Text Available It is presented a case of auricular chromoblastomycosis mimicking an eczematous lesion. The authors refer the rarity of this localization. All reported cases of auricular chromoblastomycosis have been caused by Fonsecaea pedrosoi but in the present case the etiologic agent was Phialophora verrucosa.É apresentado um caso de cromoblastomicose auricular apresentado sob forma de lesão eritemato-escamosa, tendo tido o diagnóstico clínico de eczema. Os AA discutem sobre a raridade desta localização e aspecto clínico. Embora os poucos casos relatados de cromoblastomicose auricular tenham sido causados pela Fonsecaea pedrosoi, neste o agente etiológico foi a Phialophora verrucosa.

  6. Essays on the history of brazilian dipterology: III. Three remarkable notices from the 18th century, mainly related to myiasis-producing flies (Cochliomyia and Dermatobia Ensaios sobre a história da dipterologia brasileira: III. Três notáveis notícias do século XVIII, principalmente relacionadas a moscas produtoras de miíases (Cochliomyia e Dermatobia

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    Nelson Papavero

    2012-12-01

    Full Text Available This paper registers reports about dipterans made by three Portuguese who lived in Brazil during the 18th century. Luiz Gomes Ferreira, in his book "Erário mineral" ["Mineral revenue"], wrote curious passages related with myiasis-causing flies of the genus Cochliomyia. José Rodrigues de Mello registered, in Latin verses, the folklore for curing myiases caused by Cochliomyia hominivorax in cattle. Luiz dos Santos Vilhena, in the last of his twenty letters dealing with several aspects of life in Brazil, made reference to horseflies, human bot flies and mosquitos.Este trabalho registra notícias sobre dípteros feitas por três portugueses que moraram no Brasil durante o século XVIII. Luiz Gomes Ferreyra, em seu livro "Erário mineral", escreveu curiosas passagens principalmente relacionadas com moscas causadoras de miíases do gênero Cochliomyia. José Rodrigues de Mello registrou, em versos em Latim, o folclore para curar bicheiras causadas por Cochliomyia hominivorax no gado. Luiz dos Santos Vilhena, na última de suas vinte cartas sobre vários aspectos da vida no Brasil, fez referência a mutucas, bernes e mosquitos.

  7. Dosimetry of auricular keloid irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Fitzgerald, R.H. Jr.; Taten, T.U.; Fenn, J.O.

    1982-08-01

    The incidental radiation dose of lithium fluoride thermoluminescence dosimeters was recorded during 15 treatments of patients with auricular keloids. Two half-value layers were used, and the results were compared. In both instances, the homolateral lens and thyroid received twice the contralateral dose. The oropharynx dose exceeded the thyroid dose.

  8. Cochliomyia Homnivorax in an advanced stage in the oral cavity

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    Layla Gomes

    Full Text Available Myiasis is characterized by the invasion of body or cavity tissues of live animals by larva. It is most frequently observed in underdeveloped and tropical countries, but there are cases described worldwide. Conventional treatment consists of mechanical removal of the larvae, one by one, which is a painful, embarrassing and repugnant process, both for the professional and patient. Although it is not considered rare, it has been observed that the dental professional has little knowledge for the diagnosis and treatment of this pathology. For this reason, this study reports a case of oral myiasis at an advanced stage, which affected a nine-year-old patient, treated at a medical-dental clinic. Diagnosis was based on the visual presence of Cochliomyia homnivorax larvae, diptera of the Calliphoridae family, which were between the second and third stages of development. Predisposing factors, such as the lack of information, malnutrition, poor oral hygiene, preexistenceof oral lesions and severe halitosis have a decisive influence in the appearance and progression of oral myiasis. A brief literaturereview was also conducted, in which this pathology was discussed, including the importance of early clinical diagnosis, its etiology, possible associations with other pathologies, and different types of treatment.

  9. PROBLEMÁTICA DEL GUSANO BARRENADOR DEL GANADO, Cochliomyia hominivorax

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    Elkin Forero B

    2008-08-01

    Full Text Available The new world screwworm fly, Cochliomyia hominivorax, in larval stage is an obligate parasite of mammals and humans, causing traumatic myiasis. The female fly mates once in in its lifespan, whereas the male mates several times. Accordingly eradication efforts were established in the 1950’s, using male sterilization. Screwworm eradication has been successful in North and Central America, including some Caribbean islands. However, South America is still infested. Economic costs, the length of the program, and undesirable side effects of the screwworm eradication program led to a search for alternatives control measures. The initiation of screwworm eradication in Colombia could encounter geographical, political, and mainly economical problems. This program in Colombia would require the economic support and collaboration of the USDA, organizations of international cooperation, health authorities, academic institutions, and livestock producers. Priorities for screwworm research in Colombia should be biology, epidemiology and population dynamics, together with improvement of survey methods and control technologies. The achievement of studies for establishing technical, political, economical, and environmental viability of screwworm eradication is recommended. After these data are accumulated, a commission must be assembled with public and private organizations in order to determine the real cost and benefits of eradication.

  10. Reconstrucción auricular: experiencia de 24 años Auricular reconstruction: 24 year experience

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    A. I. Mantilla Martín

    2008-06-01

    Full Text Available La oreja, debido a su situación expuesta en la cabeza, es un órgano susceptible de sufrir múltiples traumas e incluso pérdida; así mismo, es asiento de neoplasias malignas, carcinomas y melanomas que igualmente finalizan en amputación. Fuera de estas razones, la ausencia congénita del pabellón auricular es la segunda malformación facial de origen congénito más frecuente después del labio y paladar fisurados. Es común por tanto para el cirujano plástico verse frente a pacientes que consultan solicitando la solución a su deformidad. El presente artículo trata de señalar el camino a seguir dividido en cuatro etapas de acuerdo a los principios definidos por el Dr. Radford Tanzer y perfeccionados a través de los años por el Dr. Burt Brent, e ilustra el manejo de la reconstrucción en casos de microtia, amputación auricular y el uso de colgajos de fascia temporal en los casos en que la piel de la región mastoidea ha sido comprometida y no es posible usarla como elemento primario para la reconstrucción auricular.Due to its very exposed situation on both sides of the head, the auricle is very susceptible to suffer severe traumas, that will at the end cause its amputation; it´s too one of the most common sites to present malignant tumors, carcinoma and melanoma, that will also end in the surgical amputation of the ear. Congenital absence of the ear, microtia, is the second most common facial anomaly after cleft lip and palate. Not infrequently plastic surgeon confronts with patients seeking an answer for correction of their deformities. The present article tries to show a four steps method, according to the principles described first by Dr. Radford Tanzer and later improved by Dr. Burt Brent and illustrates how to manage the auricular reconstruction in cases of congenital microtia or traumatic loss of the auricle, as well as the use of the temporal fascia flap as a way to provide skin coverage, when the skin of the mastoid area has

  11. Fibrilación auricular en una paciente con megaorejuela auricular izquierda

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    Alejandro Villamil

    2007-01-01

    Full Text Available La FA constituye una de las arritmias sostenidas más frecuentes que motivan la consulta. El sustrato comprende diferentes mecanismos, entre los que se encuentra el agrandamiento auricular izquierdo. Presentamos el caso de una mujer de 33 años con antecedentes depalpitaciones, que ingresó en la guardia por FA de alta respuesta ventricular. En la radiografía de tórax se observó una deformación del borde izquierdo de la silueta cardíaca. Posteriormente,el ecocardiograma transesofágico y la resonancia magnética nuclear evidenciaron una megaorejuela aneurismática debida, probablemente, a un defecto pericárdico. La conducta fue anticoagulación oral y tratamiento con atenolol, con evolución favorable.

  12. Evaluation of the organic and functional results of tympanoplasties through a retro-auricular approach at a medical residency unit Avaliação dos resultados organofuncionais de timpanoplastias por via retroauricular em serviço de residência médica

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    José Carlos Bolini de Lima

    2011-04-01

    Full Text Available Tympanoplasty aims at rebuilding the tympanic membrane with or without middle ear functional recovery. AIM: To evaluate the surgical results of tympanoplasties with a retro-auricular surgical approach at a medical residency unit. MATERIALS AND METHODS: Thirty-nine patients with diagnosis of simple chronic otitis media were evaluated; these patients underwent tymplanoplasty by a retro-auricular approach (underlay technique at a medical residency unit. Patients were included in a prospective medical and audiologic investigation protocol that consisted of a clinical, otomicroscopic and audiometric evaluation. All procedures were supervised by training specialists otorrinolaringology. RESULTS: The rate of surgical success - full integration of the graft - was 95% of cases. Improvement of hearing, as demonstrated in audiometry, occurred in 72% of cases. Improvement in tinnitus was demonstrated subjectively on a visual analog scale in 69% of cases. CONCLUSION: Tympanoplasty through a retro-auricular approach is easy to perform. Full graft integration occurred in 95% of cases and was independent of factors deemed by many authors as relevant. The results - improvement of the quality of hearing and tinnitus - were significant.Atimpanoplastia tem por objetivo a reconstrução da membrana timpânica com ou sem reconstrução funcional da orelha média. OBJETIVO: Avaliar os resultados cirúrgicos das timpanoplastias com o acesso cirúrgico retroauricular realizadas em serviço de residência médica. MATERIAL E MÉTODO: Foram avaliados 39 pacientes com diagnóstico de otite média crônica simples submetidos à timpanoplastia por via retroauricular (técnica "underlay" em um serviço de residência médica. Os pacientes foram incluídos em um protocolo de investigação médica e audiológica prospectivo que consistiu em avaliação clínica, otomicroscópica e audiométrica. Todos os procedimentos foram supervisionados por preceptores especialistas em

  13. Artificial diets used in mass production of the New World Screwworm, Cochliomyia hominivorax

    Science.gov (United States)

    The New World screwworm, Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae), has been eradicated from North and Central America using the sterile insect technique. This success has been based on mass production of high quality screwworms using artificial diets since 1958. Many diet formulat...

  14. Implant-supported auricular prosthesis

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    Aditi Nanda

    2011-01-01

    Full Text Available Differences in the balance of shape, size, and position of body organs are immediately perceived as "looking wrong" and this perception can subject the individual to significant peer ridicule and social ostracism, often expressing as intense shame and anguish in the attitude of the afflicted. Rehabilitation of such patients can be remarkably beneficial on the individual′s self-esteem and body image. The onus of the deed lies in the hands of a team that combines artistic excellence with surgical expertise, by combining the skills of anaplastologists, surgeons, and prosthodontists. This is a review of a few surgical and prosthetic considerations in the management of auricular defect and a case description of management of a patient of microtia following similar guidelines in fabrication of the epithesis.

  15. Contribuição da acupuntura auricular no processo de abstinência das drogas psicotrópicas

    OpenAIRE

    Judite Oliveira Lima; Kelly Cristinn Saraiva; Lucas Lima Albuquerque

    2012-01-01

    Introdução: Acupuntura auricular é um método aplicado para problemas de saúde que atua por ação reflexa e apresenta resposta orgânica quando usada no microssistema da orelha. Objetivos: conhecer as drogas usadas pelos dependentes e demonstrar a contribuição da acupuntura auricular como tratamento complementar no processo de abstinência das drogas psicotrópicas. Método: estudo de campo de caráter qualitativo, aprovado pelo CEP e realizado em uma instituição do Maranhão com nove internos submet...

  16. Abundance and seasonality of Cochliomyia macellaria (Diptera: Calliphoridae in Southern Pantanal, Brazil Sazonalidade de Cochliomyia macellaria (Diptera: Calliphoridae no Pantanal Sul-mato-grossense, Brasil

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    Wilson Werner Koller

    2011-03-01

    Full Text Available Cochliomyia macellaria (Diptera: Calliphoridae, known as the secondary screwworm, occurs in the Americas and has medical-veterinary and forensic importance. This study aimed to describe the seasonal fluctuation of this species in the Pantanal region, Central-Western Brazil. From December 2004 to November 2007 fly catches using four windoriented traps baited with decaying bovine liver were carried out at the Nhumirim ranch, Nhecolândia subregion, Southern Pantanal. Traps remained active throughout the study period and collections were carried out on a weekly basis. A total of 159,397 Calliphoridae were caught and C. macellaria (57.33% was the most abundant species. C. macellaria occurred all over the year showing a bimodal behavior with peaks in May-July (late autumn/early winter and October-December (spring.Cochliomyia macellaria (Diptera: Calliphoridae, conhecida como mosca-varejeira, ocorre no continente americano e apresenta importância médico-veterinária e forense. O presente estudo teve como objetivo conhecer a flutuação sazonal dessa espécie na região do Pantanal. De dezembro/2004 a novembro/2007 foram realizadas coletas de dípteros na fazenda Nhumirim, sub-região da Nhecolândia, Pantanal sul-mato-grossense. Foram utilizadas quatro armadilhas orientadas pelo vento, iscadas com fígado bovino deteriorado. As armadilhas permaneceram ativas durante todo o período de estudo, e coletas foram realizadas semanalmente. Foram capturados 159.397 califorídeos, sendo C. macellaria (57,33% a espécie mais abundante. C. macellaria foi observada em todos os meses do ano, apresentando comportamento bimodal com picos populacionais em maio/julho (final de outono/início de inverno e outubro/dezembro (primavera.

  17. Rara miasis maxilar por Cochliomyia hominivorax. Reporte de caso, actualidad y entomología

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    Santiago Reinoso-Quezada

    2016-04-01

    Full Text Available La miasis maxilar es un raro padecimiento tropical y endémico de varias zonas del mundo, propio de algunos mamíferos, y el hombre no es la excepción. A continuación presentamos el primer reporte de miasis de este tipo en Ecuador, caracterizamos una masiva invasión larvaria y analizamos casos similares reportados en la literatura médica.

  18. Patient with Tracheostomy Parasitized in Hospital by Larvae of the Screwworm, Cochliomyia hominivorax

    Science.gov (United States)

    Batista-da-Silva, José A.; Borja, Gonzalo E. M.; Queiroz, Margareth M. C.

    2011-01-01

    Myiasis is the infestation of living vertebrates by fly larvae that feed for at least part of their development on the host's dead or living tissues, body substances, or ingested food. The occurrences of traumatic myiasis in humans and animals in urban and rural environments represent serious economic and public health concerns. This study reports a 49-year-old tracheostomized man undergoing chemotherapy treatment who was parasitized in the hospital in São Gonçalo, Rio de Janeiro, Brazil, by larvae of the screwworm, Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae) in the thoracic cavity. PMID:22243525

  19. Implant-Retained Auricular Prosthesis: A Case Report

    OpenAIRE

    Ozturk, A. Nilgun; Usumez, Aslihan; Tosun, Zekeriya

    2010-01-01

    Extraoral implant retained prosthesis have been proven to be a predictable treatment option for maxillofacial rehabilitation. This case report describes the clinical and laboratory procedures for fabricating an auricular prosthesis. In this case report, an auricular prosthesis was fabricated for a patient who lost the left and right external ear in an electrical burn. Extraoral implants and bar-and-clip retention for the proper connection of the auricular prosthesis to implant were used. This...

  20. Characterization and utilization of microsatellite loci in the New World screwworm fly, Cochliomyia hominivorax.

    Science.gov (United States)

    Griffiths, A M; Evans, L M; Stevens, J R

    2009-06-01

    New World screwworm populations in North and Central America have been the targets of virtually continuous eradication attempts by sterile insect technique (SIT) since the 1950s. Nevertheless, in some areas, such as Jamaica, SIT control programmes have failed. Reasons for the failure of SIT-based control programmes in some locations are unknown, but it has been hypothesized that failure may be related to mating incompatibility between sterile and wild fly populations or to the existence of sexually incompatible cryptic species. This paper outlines the development of a suite of four new microsatellite loci which can be used to study intra-specific relationships between populations of Cochliomyia hominivorax from the Caribbean and South America, which represent those populations involved in, or earmarked for, forthcoming SIT control. Cross-amplification with the secondary screwworm, Cochliomyia macellaria, was also successful with three of the new loci. We present results which suggest that populations from Trinidad and Jamaica form distinct groupings of flies and that C. hominivorax from Trinidad appears particularly distinct. PMID:19335825

  1. Comparative morphology of the spermathecae of some species of Chrysomya Robineau-Desvoidy and Cochliomyia Townsend (Diptera, Calliphoridae

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    Érica Sevilha Harterreiten-Souza

    2012-03-01

    Full Text Available Comparative morphology of the spermathecae of some species of Chrysomya Robineau-Desvoidy and Cochliomyia Townsend (Diptera, Calliphoridae. Little is known about the morphology of the chitinized structures of the spermathecae of the Calliphoridae. In this work, the spermathecae of Chrysomya albiceps Wiedemann, 1819, C. megacephala Fabricius, 1794, Cochliomyia macellaria Fabricius, 1775 and C. hominivorax Coquerel, 1858 are described and illustrated. The occurrence in one species of four spermathecae, an atypical form for blow flies, was recorded for the first time. The analysis of these structures will allow a better understanding of this group as well as provide taxonomic characters for future phylogenetic studies.Morfologia comparada das espermatecas de espécies de Chrysomya Robineau-Desvoidy e Cochliomyia Townsend (Diptera, Calliphoridae. Pouco se conhece sobre a morfologia das estruturas quitinizadas das espermatecas de Calliphoridae. Nesse trabalho as espermatecas de Chrysomya albiceps Wiedemann, 1819, C. megacephala Fabricius, 1794, Cochliomyia macellaria Fabricius, 1775 e C. hominivorax Coquerel, 1858 são descritas e ilustradas. Foi registrada pela primeira vez a ocorrência em uma espécie com quatro espermatecas, uma forma atípica em califorídeos. A análise dessas estruturas possibilitará uma melhor compreensão do grupo e fornecerá caracteres taxonômicos para futuros estudos filogenéticos.

  2. Avenues for rehabilitation of auricular defects

    OpenAIRE

    Aditi Nanda; Veena Jain; Sri Krishna Kabra

    2012-01-01

    Irrespective of the cause, abnormalities in shape, size, and position of body organs are often perceived as looking wrong. This perception can subject the individual to significant peer ridicule and social ostracism. Rehabilitation of patients with auricular defects can either be done by reconstructive surgery or by prosthetic means. The article draws a comparison between the implant-supported prosthesis and reconstructive surgery, listing the benefits, limitations, indications and contraindi...

  3. Auricular electrical stimulation and dental pain threshold.

    OpenAIRE

    Simmons, M. S.; Oleson, T. D.

    1993-01-01

    A modified double-blind evaluation of naloxone reversibility of dental analgesia produced by auricular electrical stimulation (AES) was examined in 40 subjects assigned randomly to one of four groups: AES followed by saline (AS), AES followed by naloxone (AN), placebo AES followed by saline (PS), and placebo AES followed by naloxone (PN). Dental pain threshold was tested using a hand-held dental pulp tester. A second investigator administered the true or placebo AES using an electrical stimul...

  4. A new DNA extraction protocol for screwworm fly Cochliomyia species. (Diptera: Calliphoridae.

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    Gustavo eEcheverría-Fonseca

    2015-01-01

    Full Text Available Modifications to the DNA isolation protocol from Cochliomyia spp., are suggested based on the Chelex® 100 reactive. To apply the sterile insect technique (SIT program it is necessary to study the molecular variations of endemic populations with efficient, fast and low costs techniques. The test samples were collected in the Pichincha province of Ecuador. The isolation protocol had 3 steps: a pretreatment (optional, b mechanic and chemical lysis, c two incubations; then the supernatant were separated by centrifugation. Furthermore, variations in concentrations of magnesium chloride present in the master mix were evaluated. Results showed a high efficiency in isolation with approximately 1.20 hours of manipulation (without pretreatment. Additionally, the quality of the amplicon that was visualized on 2% agarose (w/v showed that the magnesium chloride concentration was influential in the PCR reaction mix.

  5. Electrospinning Auricular Shaped Scaffolds for Tissue Engineering

    OpenAIRE

    Walser, Jochen; Caversaccio, Marco; Ferguson, Stephen J.

    2013-01-01

    Poly(ɛ)caprolactone scaffolds have been electrospun directly into an auricular shaped conductive mould. Bovine chondrocytes were harvested from articular cartilage and seeded onto 16 of the produced scaffolds, which received either an ethanol (group A) or a plasma treatment (group B) for sterilisation before seeding. The seeded scaffolds were cultured for 3 weeks in vitro and analysed with regard to total DNA and GAG content as well as the expression of AGG, COL1, COL2, MMP3 and MMP13. Rap...

  6. Avenues for rehabilitation of auricular defects

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    Aditi Nanda

    2012-01-01

    Full Text Available Irrespective of the cause, abnormalities in shape, size, and position of body organs are often perceived as looking wrong. This perception can subject the individual to significant peer ridicule and social ostracism. Rehabilitation of patients with auricular defects can either be done by reconstructive surgery or by prosthetic means. The article draws a comparison between the implant-supported prosthesis and reconstructive surgery, listing the benefits, limitations, indications and contraindications of both the techniques. As both the available techniques give excellent results in appropriately selected situations, the restorative team must present all the alternatives to the patient and choose judiciously the better of the two.

  7. Greater auricular nerve masquerading as lymph node.

    Science.gov (United States)

    Saxena, Shilpi; Deb, Prabal; Nijhawan, Vijay Shrawan; Kharayat, Veena; Verma, Rajesh

    2015-01-01

    Hansen's disease is on the verge of being eliminated from India and often missed by clinicians due to low index of suspicion. We present an unusual case in which greater auricular nerve thickening masqueraded as enlarged lymph node in the neck. The patient was referred for fine needle aspiration cytology, which revealed epithelioid cell granulomas suggestive of Hansen's disease. Further clinical examination and investigations including the skin biopsy confirmed the disease, highlighting the role of pathologist in the management of such unusual presentation of a common disease. PMID:26229249

  8. Efficacy of triple therapy in auricular keloids

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    Reuben F De Sousa

    2014-01-01

    Full Text Available Background: Keloids are characterised by their continued growth following trauma, extension into normal tissue and their high recurrence rate following excision. Auricular keloids are common following ear piercing or flame burns. These lesions are highly conspicuous and cosmetically unappealing. Multiple methods including surgery, radiotherapy, antimitotic agents, silicone sheet, pressure clips and cryotherapy have been advocated. The risk of recurrence and the need to prevent distortion of the three-dimensional structure of the ear following resection is a challenge to the cutaneous surgeon. Objectives: To devise a standard protocol for management of auricular keloids with minimal distortion and recurrence. Setting and Design: The patients underwent day-care surgery and subsequent out-patient follow-up for a minimum period of 1 year. Methods: Ten patients presenting with 22 ear keloids were enrolled into a keloid protocol: (a surgical excision and keloid rind flap cover with (b intra-operative and post-operative intra-lesional steroid and (c silicone sheet application. Subjective assessment on follow-up was using Patient Observer Scar Assessment Scale and objective assessment was by Beausang scale. Statistical Analysis used: Microsoft Excel and Statistical Package for the Social Sciences (SPSS. Kaplan-Meier survival analysis curve used to calculate Recurrence Free period. Results: Two out of 22 (9.1% keloids developed post-excision recurrence after a mean follow -up period of 16 months. The average keloid recurrence free interval was 21 months. Conclusion: Triple combination therapy for keloids on the ear is a simple technique for management with preservation of contour of the ear and a low recurrence rate.

  9. Essays on the history of brazilian dipterology: III. Three remarkable notices from the 18th century, mainly related to myiasis-producing flies (Cochliomyia and Dermatobia

    Directory of Open Access Journals (Sweden)

    Nelson Papavero

    2012-12-01

    Full Text Available This paper registers reports about dipterans made by three Portuguese who lived in Brazil during the 18th century. Luiz Gomes Ferreira, in his book "Erário mineral" ["Mineral revenue"], wrote curious passages related with myiasis-causing flies of the genus Cochliomyia. José Rodrigues de Mello registered, in Latin verses, the folklore for curing myiases caused by Cochliomyia hominivorax in cattle. Luiz dos Santos Vilhena, in the last of his twenty letters dealing with several aspects of life in Brazil, made reference to horseflies, human bot flies and mosquitos.

  10. Dietas larvais alternativas para criação massal da mosca da bicheira, Cochliomyia hominivorax

    Directory of Open Access Journals (Sweden)

    Thiago Mastrangelo

    2014-04-01

    Full Text Available A criação massal da mosca da bicheira, Cochliomyia hominivorax (Diptera: Calliphoridae, para programas que utilizam a Técnica do Inseto Estéril nas Américas faz parte de um dos maiores programas do mundo de criação de insetos em larga escala. A maior parte do custo e do trabalho necessários para a produção massal está relacionada com a dieta larval, o que torna importante o seu aprimoramento levando-se em conta sua eficiência, custo e praticidade. Neste trabalho, foram realizados dois bioensaios com dietas alternativas feitas a partir de produtos disponíveis no mercado brasileiro com o objetivo de avaliar a viabilidade e eficiência dessas dietas para criações de mosca da bicheira no Brasil. Foram testadas duas dietas líquidas (tendo como bulking agents bagaço de cana ou fibra de coco, uma de carne, e outra de gel. Os parâmetros biológicos (peso das larvas, viabilidade larval, peso de pupas, porcentagem de emergência de adultos e razão sexual estiveram, em todos os casos, dentro de parâmetros satisfatórios para a criação laboratorial de C. hominivorax e as dietas não diferiram estatisticamente entre si. Devido a vantagens importantes, como alta viabilidade larval e menor custo, recomenda-se a dieta de gel para as criações de larvas da mosca da bicheira no Brasil.

  11. Sexual dimorphism in auricular surface projection and postauricular sulcus morphology.

    Science.gov (United States)

    Wescott, Daniel J

    2015-05-01

    The presence of an elevated auricular surface and a postauricular sulcus is presented in numerous reference books as osteological indicators of sex, but the validity of these traits has not been adequately evaluated. The ilia of 322 (181 male, 141 female) adults were examined, the auricular surface was scored as completely, partially, or nonelevated, and the postauricular sulcus was scored as present or absent. Complete elevation occurred almost exclusively in females (67% of females and 0.6% of males). The postauricular sulcus was present in 27% of males and 85% of females. When present, an elevated auricular surface is a reliable indicator that the individual is female. However, the absence of the trait is a less reliable indicator of sex. The postauricular sulcus is a moderately accurate estimator of sex.

  12. Free Auricular Composite Graft for Acquired Nasal Stenosis

    Science.gov (United States)

    Riley, Charles A.; Lawlor, Claire M.; Gray, Mingyang Liu; Graham, H. Devon

    2016-01-01

    Background: Acquired nasal stenosis poses a reconstructive challenge for the facial plastic surgeon. Many surgical options are available, ranging from primary closure to skin grafts to free flap reconstruction for complex defects. The free auricular composite graft is a single-stage procedure that can be used to repair nasal vestibular stenosis causing nasal obstruction. Case Report: We present the case of a patient with acquired nasal stenosis as a result of prolonged nasal tampon placement secondary to severe epistaxis and subsequent nasal vestibular infection. Repair via auricular composite graft was successful, and we provide a thorough explanation of graft design and operative technique. Conclusion: Free auricular composite grafts can produce desirable functional and aesthetic outcomes and should be considered in patients presenting with acquired nasal stenosis. PMID:27303225

  13. Preliminary studies on the early quality identification of Auricularia auricular

    Institute of Scientific and Technical Information of China (English)

    LI Ling; DING Jun-nan; LUO Li; ZOU Li; Wang Xiang-li; Zhang Gui-hua

    2005-01-01

    In production industry of Auricularia auricular, the varieties quality is most important impact factor on output. For evaluating the early quality of the edible fungus, 9 varieties of Auricularia auricular (Au9, CF09, CF05, 29, 916, chang10, chang7, Au.Japanese and 8808) were cultured on the medium consists of potato dextrose agar (PDA) and sawdust to test their mycelium growth rate, endurance to high temperature, resistance to mildew, assimilation of nutriment, and resistance to drought. The result showed that the mycelium of Chang 10, CF09, 29 and Au.Japanese varieties had the eminent characteristics such as short lifespan, stronger assimilation of nutriment, and endurance to high temperature and steady growth. These four varieties are determined as superiority varieties of Auricularia auricular in accordance with the research results.

  14. Facio-auricular vertebral syndrome-a case report

    Directory of Open Access Journals (Sweden)

    Reddy M

    2005-01-01

    Full Text Available Facio Auricular Vertebral (FAV or Goldenhar syndrome is a very rare kind of syndromic deafness and is inherited as autosomal dominant. A study was taken up to understand the prevalence of this syndrome in children below the age of 14 years with hearing loss. Out of 1073 children with hearing impairment, Goldenhar syndrome was observed only in 1 (0.09% case. The child suffered severe hearing loss. Facial paralysis and hemifacial microsomia were prominent features observed in the child. Facio-Auricular-Vertebral syndrome is therefore synonymously used with Goldenhar syndrome.

  15. Screwworms, Cochliomyia hominivorax, reared for mass release do not carry and spread foot-and-mouth disease virus and classical swine fever virus

    Science.gov (United States)

    Transporting live screwworms Cochliomyia hominivorax Coquerel for developing new strains from countries where foot-and-mouth disease (FMD) and classical swine fever (CSF) are endemic, to the mass rearing facilities in Mexico and Panama may introduce these exotic diseases. This study was conducted to...

  16. Provision of Auricular Acupuncture and Acupressure in a University Setting

    Science.gov (United States)

    Oyola-Santiago, Tamara; Knopf, Rachel; Robin, Tracy; Harvey, Kristen

    2013-01-01

    Auricular acupuncture using the National Acupuncture Detoxification Association (NADA) protocol stimulates 5 points in each ear--the Shen Men, sympathetic nervous system, liver, kidney, and lung. This protocol is also known as Acu Detox, and has been used for recovery in community-based settings and drug use treatment programs. It has also been…

  17. Treatment of Facial Chloasma by Auricular Pressure in41 Cases

    Institute of Scientific and Technical Information of China (English)

    LIU Guang-xia; XIAO Yuan-chun

    2003-01-01

    According to differentiating syndrome and dividing patter, 41 cases of Facial Chloasma by Auricular Pressure in Shen ( MA-AH), Fei ( MA-IC 1 ), Neifenmi ( MA-IC 3 ), Luanchao ( MA-AT), Mianjia (MA-L) and Xia' erbei(MA-IC), the total effective rate was 87.8%.

  18. A Biodesigned Nanocomposite Biomaterial for Auricular Cartilage Reconstruction.

    Science.gov (United States)

    Nayyer, Leila; Jell, Gavin; Esmaeili, Ali; Birchall, Martin; Seifalian, Alexander M

    2016-05-01

    Current biomaterials for auricular replacement are associated with high rates of infection and extrusion. The development of new auricular biomaterials that mimic the mechanical properties of native tissue and promote desirable cellular interactions may prevent implant failure. A porous 3D nanocomposite scaffold (NS) based on POSS-PCU (polyhedral oligomeric silsesquioxane nanocage into polycarbonate based urea-urethane) is developed with an elastic modulus similar to native ear. In vitro biological interactions on this NS reveal greater protein adsorption, increased fibroblast adhesion, proliferation, and collagen production compared with Medpor (the current synthetic auricular implant). In vivo, the POSS-PCU with larger pores (NS2; 150-250 μm) have greater tissue ingrowth (≈5.8× and ≈1.4 × increase) than the POSS-PCU with smaller pores (NS1; 100-50 μm) and when compared to Medpor (>100 μm). The NS2 with the larger pores demonstrates a reduced fibrotic encapsulation compared with NS1 and Medpor (≈4.1× and ≈1.6×, respectively; P NS1 (12 weeks postimplantation). The lack of chronic inflammatory response for all materials may indicate that the elastic modulus and pore size of the implant scaffold could be important design considerations for influencing fibrotic responses to auricular and other soft tissue implants. PMID:26992039

  19. Prefabricated stock trays for impression of auricular region.

    Science.gov (United States)

    Vibha, Shetty; Anandkrishna, G N; Anupam, Purwar; Namratha, N

    2010-06-01

    The conventional methods of impression making for maxillofacial defects are cumbersome and time consuming for both patient and operator. This study focuses upon standardizing and simplifying the impression making methodology for auricular prosthesis with the help of prefabricated stock trays for auricular region. The stock trays were designed on positive replicas of anatomical structures, broadly divided into long and narrow, short and broad and long and broad ear. For each stock tray, impressions of auricle, of patients of different morphology were made with plastic funnels of different shape and size ensuring at least 6 mm of space between the anatomical part and inner surface of funnel and master cast was obtained. Subsequent adaptation of wax was done and fabrications of stock stainless steel trays were done. A standardized stock tray for making of auricular impressions was developed. From this innovative technical procedure it is possible to get an accurate impression of auricular defects now by the use of prefabricated stock trays rather than the cumbersome conventional method. PMID:21629455

  20. Auricular-Plaster Therapy for Treatment of IBS

    Institute of Scientific and Technical Information of China (English)

    敖学艳; 王宁

    2004-01-01

    @@ Irritable bowel syndrome (IBS), a disease of the digestive system related to mental factors, is clinically characterized by diarrhea (or alternation of diarrhea and constipation) and abdominal pain. In recent years, the authors have used auricular-plaster therapy plus pressing on the back-shu points to treat IBS, and obtained good therapeutic results.

  1. Fibrilación auricular en el postoperatorio de cirugía cardíaca: Prevalencia y tiempo de internación

    Directory of Open Access Journals (Sweden)

    Alejandro E. Contreras

    2010-08-01

    Full Text Available La fibrilación auricular es el trastorno del ritmo más frecuente luego de la cirugía cardíaca. En estudios previos se ha asociado a prolongación de la internación, aumento en los costos e incremento en la mortalidad. El objetivo de este estudio fue conocer la prevalencia de fibrilación auricular en el postoperatorio de cirugía cardíaca y determinar el efecto en el tiempo de estadía hospitalaria. Se analizaron retrospectivamente las historias clínicas de pacientes sometidos a cirugía cardíaca consecutivamente (de revascularización miocárdica, valvulares o ambas entre enero 2006 y noviembre 2008. El punto final evaluado en el postoperatorio fue la presencia de fibrilación auricular. Se dividió a la muestra en dos grupos según tuvieran o no fibrilación auricular, y se compararon las variables clínicas y el tiempo de estadía hospitalaria. Ciento setenta y dos pacientes fueron operados en este período. Se excluyeron del análisis siete pacientes por falta de datos. La edad media fue 64.2 ± 9.5 años, con predominio del sexo masculino. La fibrilación auricular fue la complicación más frecuente (23.6%. El tiempo promedio de internación fue 6.7 ± 4.6 días. No hubo diferencias relevantes al comparar la estadía hospitalaria entre los grupos con o sin fibrilación auricular, 7.5 ± 4.1 días vs. 6.5 ± 4.7 días respectivamente, p = 0.21. La presencia de fibrilación auricular no prolongó la hospitalización. Probablemente una estrategia de prevención indiscriminada no sería costo-efectiva.

  2. [Cutaneous myiasis by Cochliomyia hominivorax (Coquerel) (Diptera Calliphoridae) in Hospital Universidad del Norte, Soledad, Atlántico].

    Science.gov (United States)

    de la Ossa, Napoleón; Castro, Luis Eduardo; Visbal, Lila; Santos, Ana María; Díaz, Esther; Romero-Vivas, Claudia M E

    2009-03-01

    Human myiasis is the parasitism of human tissues by fly larvae. Diagnoses are based on clinical pattern of tissue damage and presence of insect stages. Herein, a case myiasis is described in a seven-year-old female child. She presented with fever associated with abscessed scalp lesions containing exposed larvae. Severe pediculosis was also observed. The patient was hospitalized and treated with clindamycin, gentamicin (for bacterial secondary infections) and ivermectin (treatment for lice) after which the patient showed clinical improvement and was discharged four days later. Since human myiasis can be caused by a number of different species, larvae were collected from the patient and identified as those of Cochliomyia hominivorax (Diptera: Calliphoridae). Because other cases of coinfestation of flies and lice are on record, health workers are to be alerted about the possible pediculosis-myasis risk.

  3. Effects of Auricular Acupressure on Body Weight Parameters in Patients with Chronic Schizophrenia

    OpenAIRE

    Han-Yi Ching; Shang-Liang Wu; Wen-Chi Chen; Ching-Liang Hsieh

    2012-01-01

    Auricular acupressure is widely used in complementary and alternative medicine to reduce body weight, but little is known about the effects of auricular acupressure on body weight parameters in patients with chronic schizophrenia. The purpose of this study was to evaluate the effects of auricular acupressure on body weight parameters in patients with chronic schizophrenia. Eighty-six inpatients with schizophrenia were recruited from chronic wards in a psychiatric center. The participants were...

  4. The History, Mechanism, and Clinical Application of Auricular Therapy in Traditional Chinese Medicine

    OpenAIRE

    Pu-Wei Hou; Hsin-Cheng Hsu; Yi-Wen Lin; Nou-Ying Tang; Chin-Yi Cheng; Ching-Liang Hsieh

    2015-01-01

    Auricular therapy includes acupuncture, electroacupuncture, acupressure, lasering, cauterization, moxibustion, and bloodletting in the auricle. For 2500 years, people have employed auricular therapy for treating diseases, but the methods have been limited to bloodletting and cauterization. Only after 1957, the international scientific community became aware that the map of the ear resembles an inverted fetus, its introduction has led to auricular acupuncture (AA) becoming a more systemic appr...

  5. Treatment of Dysmenorrhea by Acupuncture plus Auricular Acupuncture

    Institute of Scientific and Technical Information of China (English)

    CAI Zhi-jun; LI Fang; LU Mei; XIAO Yuan-chun

    2004-01-01

    采用针刺和电耳针相结合的方法治疗气滞血瘀型痛经38例,取得良好疗效,有效率达974%.%The authors adopted acupuncture plus auricular electro-acupuncture to treat 38 cases of dysmenorrhea belonging to qi stagnation and blood stasis pattern, the better therapeutic effect was achieved, with the effective rate of 97.4%.

  6. Screwworms, Cochliomyia hominivorax, Reared for Mass Release Do Not Carry and Spread Foot-and-Mouth Disease Virus and Classical Swine Fever Virus

    OpenAIRE

    Chaudhury, M. F.; Ward, G. B.; Skoda, S. R.; Deng, M Y; Welch, J. B.; McKenna, T S

    2008-01-01

    Experiments were done to determine if transporting live screwworms Cochliomyia hominivorax Coquerel (Diptera: Calliphoridae) for developing new strains from countries where foot-and-mouth disease and classical swine fever are endemic, to the mass rearing facilities in Mexico and Panama, may introduce these exotic diseases into these countries. Are screwworms capable of harboring and spreading foot-and-mouth disease virus (FMDV) and classical swine fever virus (CSFV) when they are grown in vir...

  7. The History, Mechanism, and Clinical Application of Auricular Therapy in Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Pu-Wei Hou

    2015-01-01

    Full Text Available Auricular therapy includes acupuncture, electroacupuncture, acupressure, lasering, cauterization, moxibustion, and bloodletting in the auricle. For 2500 years, people have employed auricular therapy for treating diseases, but the methods have been limited to bloodletting and cauterization. Only after 1957, the international scientific community became aware that the map of the ear resembles an inverted fetus, its introduction has led to auricular acupuncture (AA becoming a more systemic approach, and, following the identification and standardization of more precise points, AA has been employed in clinical applications. The mechanisms of AA are considered to have a close relationship with the autonomic nervous system, the neuroendocrine system, neuroimmunological factors, neuroinflammation, and neural reflex, as well as antioxidation. Auricular therapy has been applied, for example, for pain relief, for the treatment of epilepsy, anxiety, and obesity, and for improving sleep quality. However, the mechanisms and evidence for auricular therapy warrant further study.

  8. Adjuvant auricular electroacupuncture and autogenic training in rheumatoid arthritis: a randomized controlled trial. Auricular acupuncture and autogenic training in rheumatoid arthritis

    DEFF Research Database (Denmark)

    Bernateck, M; Becker, M; Schwake, C;

    2008-01-01

    BACKGROUND: In contrast to psychological interventions the usefulness of acupuncture as an adjuvant therapy in rheumatoid arthritis (RA) has not yet been demonstrated. OBJECTIVE: The efficacy of auricular electroacupuncture (EA) was directly compared with autogenic training (AT). METHODS: Patients...

  9. Contribuição da acupuntura auricular no processo de abstinência das drogas psicotrópicas

    Directory of Open Access Journals (Sweden)

    Judite Oliveira Lima

    2012-06-01

    Full Text Available Introdução: Acupuntura auricular é um método aplicado para problemas de saúde que atua por ação reflexa e apresenta resposta orgânica quando usada no microssistema da orelha. Objetivos: conhecer as drogas usadas pelos dependentes e demonstrar a contribuição da acupuntura auricular como tratamento complementar no processo de abstinência das drogas psicotrópicas. Método: estudo de campo de caráter qualitativo, aprovado pelo CEP e realizado em uma instituição do Maranhão com nove internos submetidos ao método a partir do quarto mês em tratamento para dependência química. Cientes dos objetivos da pesquisa excluiu-se participantes que usavam medicação coadjuvante como anti-hipertensivos, cardiotônicos e outros. Durante as entrevistas aplicou–se um roteiro semi-estruturado cujos depoimentos foram gravadas para escuta atentiva e análise, a posteriori. Resultados: emergiram quatro categorias como tipos de psicotrópicos usados pelos participantes nas quais foram citadas como as drogas mais consumidas, o álcool (100%, maconha(100%, seguida de cocaína(60% e crack(40%; para a acupuntura auricular atuando na abstenção das drogas, referiram sintomatologias como nervosismo, depressão,mialgias, impaciência, ansiedade, câimbras, alterações no ritmo do sono e inquietação que caracterizam a dependência psicológica manifestados devido à interrupção do uso exagerado ou prolongado das drogas, porém apontaram como benefícios para a saúde os efeitos positivos do método já que a terapia trouxe equilíbrio emocional, alívio das dores e regularidade da fome e sono; quanto a recomendação do uso para outras pessoas referiram aprovação da terapia que merece ser divulgada, pois perceberam contribuições expressivas da acupuntura auricular, como tratamento complementar. Conclusão: acupuntura auricular é relevante na efetivação da libertação da dependência por drogas psicotrópicas, enquanto terapia complementar que

  10. Pliegue diagonal del lóbulo auricular (de Frank y su relación con enfermedad coronaria

    Directory of Open Access Journals (Sweden)

    Manuel Agustín Paz

    2014-07-01

    Full Text Available La presencia de pliegue diagonal auricular debe alertar al médico para entender su asociación con la enfermedad cardíaca coronaria y la enfermedad isquémica del corazón, especialmente en aquellos pacientes asintomáticos o pacientes con factores de riesgo tradicionales y no tradicionales. Por lo tanto, esta anormalidad puede ser interpretada como un "marcador cutáneo" de la enfermedad cardíaca coronaria. Este signo también podría servir para identificar mejor a los grupos de alto riesgo cardiovascular y para comenzar con la implementación de las medidas de las estrategias de prevención. Hay otros signos clínicos, además del pliegue de la oreja, que pueden reflejar el envejecimiento arterial y aterosclerosis, independientemente del número, duración o alcance de los factores de riesgo cardiovascular tradicionales. El hallazgo de pliegue auricular no debe sustituir a una historia clínica completa, la aplicación de métodos detallados, exámenes de laboratorio y físicos utilizados con excelente rendimiento en el diagnóstico de la enfermedad coronaria en la actualidad.

  11. Sutura metálica con aguja doble armada para reconstrucción auricular: experiencia en su fabricación y uso

    Directory of Open Access Journals (Sweden)

    C.A. Erazo-Cortés

    2013-09-01

    Full Text Available Las técnicas de reconstrucción auricular que involucran tejidos autólogos utilizan suturas de acero inoxidable especialmente diseñadas para la construcción del marco cartilaginoso tridimensional que no están disponibles en nuestro país. En el presente trabajo describimos una técnica original para la confección de una sutura de estas características en base a materiales aprobados para uso médico y comparamos su resistencia antes y después de ser sometida a esterilización. Incluimos en el estudio 30 suturas confeccionadas según la técnica descrita y divididas en 3 grupos: sin esterilizar (control, esterilizadas por vapor y esterilizadas por gas (oxido de etileno. La fuerza de ruptura promedio del grupo control fue de 10 Newton, la del esterilizado por vapor fue de 24.1 Newton y la del esterilizado por gas fue de 23.9 Newton. El aumento en la resistencia de las suturas después de la esterilización fue estadísticamente significativo. Concluimos que es posible fabricar artesanalmente una sutura con características adecuadas para la reconstrucción auricular a un bajo costo y que actualmente es de uso habitual en nuestro Servicio para este tipo de procedimientos.

  12. Experiencia en reconstrucción auricular en cáncer de piel con colgajo en "quesadilla" Experience in auricle reconstruction after skin carcinoma with "quesadilla" flap

    Directory of Open Access Journals (Sweden)

    C. Gutiérrez Gómez

    2008-06-01

    Full Text Available La reconstrucción auricular es una de las más difíciles ya que implica reproducir las sofisticadas y delicadas formas del pabellón auricular. Cuando hay que resecar piel en la oreja por un cáncer cutáneo y dejamos expuesto el cartílago, sin pericondrio, suele suceder que al colocar injertos no hay una integración adecuada de los mismos por las caprichosas formas y relieves del pabellón auricular; cuando es necesario resecar el pericondrio estamos obligados a cubrir el defecto con un colgajo y no con un simple injerto. Frente a esta dificultad técnica, diseñamos un colgajo ricamente vascularizado que preserva el cartílago no afectado con una buena cubierta y al mismo tiempo respeta la anatomía de la oreja. Para la cobertura del cartílago auricular anterior usamos un colgajo fasciocutáneo posterior que se asemeja a un plato típico de la cocina mexicana que llamamos "quesadilla", donde el cartílago por su color blanco recuerda el queso y el gran colgajo fasciocutaneo recuerda la tortilla que cubre al queso. Este colgajo incluye la piel enrollada del hélix, que en un segundo tiempo retornará a su lugar de origen anatómico mediante una z-plastía asimétrica. Presentamos, de entre una serie de 13 pacientes con carcinoma de pabellón auricular, 2 casos resueltos mediante esta técnica.Auricle reconstruction is one of the most difficult techniques because of the sophisticated and delicates forms of the ear. When we need to remove the auricular skin, preserving the cartilage is very important to keep the shape of the auricle. If treating an auricular skin cancer we find an unaffected cartilage, we can use a skin grafting, but in such delicates forms and curves many times it results inappropriate or the lack of pericondrium difficult skin graft integration. When pericondrium is affected, we will need a skin flap to cover de defect. We designed a rich vascularized flap that preserves the unaffected cartilage with an adequate coverage

  13. Clinical aspects and dynamics of auricular parasitosis in Gir cattle Aspectos clínicos e dinâmica de parasitoses auriculares em bovinos da raça Gir

    Directory of Open Access Journals (Sweden)

    Patrícia V.B. Leite

    2013-03-01

    Full Text Available We evaluated the dynamics of ear infestations caused by Rhabditis spp. and Raillietia spp., which were correlated with animal age, intensity of clinical signs and climate factors. Sixty-four Gir cattle were distributed into three groups: GA - 23 calves with 4 to 6 months of age; GB - 18 calves with 7 to 12 months of age; and GC - 23 heifers with 13 to 33 months of age. Five samplings, defined as S1, S2, S3, S4 and S5 were performed every three months from August 2008 to August 2009. The ear secretion was collected using the auricular washing method for the right ear and a swab for the left ear. A clinical assessment of the animals was performed, and they were classified according to the presence and severity of otitis. The highest relative frequency of rhabditosis was 52.2% in GC at the last sampling. In the first sampling, 42.2% of the animals were infested by Raillietia spp. The older cattle were more susceptible to infestations by both parasites. No correlation of Rhabditis spp. and Raillietia spp. parasitism with climate factors was found. The results showed that both parasites could infest Gir cattle, and in most cases, there was no co-infestation. Only older animals parasitized by the nematode showed clinical signs of the disease.Avaliou-se a dinâmica da infestação auricular causada por Rhabditis spp. e por Raillietia spp., relacionando-a com a idade dos animais, com a intensidade dos sinais clínicos e com os fatores climáticos. Utilizaram-se 64 bovinos Gir, distribuídos em três grupos: GA - 23 bezerros de quatro a seis meses de idade, GB - 18 bezerros de sete a 12 meses e GC - 23 novilhas de 13 a 33 meses. Foram feitas cinco coletas a cada três meses. A secreção auricular foi coletada utilizando o método de lavagem auricular na orelha direita e um swab na orelha esquerda. Fez-se avaliação clínica dos animais classificando-os de acordo com a presença e gravidade da otite. A maior frequência relativa da rhabditiose

  14. Comparison of two impression techniques for auricular prosthesis: Pilot study

    Directory of Open Access Journals (Sweden)

    Kasim Mohamed, MDS

    2013-11-01

    Full Text Available The purpose of this article was to compare the accuracy of a new impression technique, the triple-layer impression technique (TLIT, with the conventional impression technique (CIT to fabricate an auricular prosthesis. Fifteen male subjects (aged 22–45 yr were selected. Ten markings were made on the subject's ear (super aurale [sa], sub aurale [sba], pre aurale [pra], post aurale [poa], A, A1, B, B1, C, and C1 and five measurements (sa'sba, pra–poa, A–A1, B–B1, and C–C1 were made. Custom-made trays were used to record impression in CIT and TLIT. Impressions were made using alginate, and models were cast with type IV gypsum product. Markings were transferred on the cast. Measurements were rechecked on the models. Distribution analysis of difference in measurements between the two impression techniques and the subject's actual values was evaluated. Sign test was used to analyze the statistical significance. Statistically significant differences were found in measurements A–A1, B–B1, and C–C1 between the two techniques when compared with the subject's actual dimensions (p < 0.01. TLIT was found to produce accurate models when compared with CIT. The TLIT used in the study was cost effective, less technique sensitive, and tailor made to reduce chairside orientation time during wax try-in appointments for rehabilitating patients, especially those with unilateral auricular defects.

  15. FIBRILACIÓN AURICULAR ISQUÉMICA / Ischemic atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Jose R. Ruiz Arroyo

    2013-07-01

    Full Text Available Resumen: La fibrilación auricular es la arritmia más frecuente en el período peri-infarto agudo de miocardio, aunque su presencia asociada tan solo a la fase de isquemia aguda y su inmediato cese tras una revascularización precoz y efectiva es testimonial en la literatura, con la consiguiente falta de evidencia para su posterior tratamiento. Se presenta un caso clínico en el que el intervencionismo coronario precoz consiguió la cardioversión a ritmo sinusal de una fibrilación auricular en el curso de un infarto agudo de miocardio, posteriormente se discute la estrategia a seguir en torno a la arritmia en un paciente con buena evolución clínica tras el suceso. / Abstract: Atrial fibrillation is the most common arrhythmia in the periacute myocardial infarc-tion period, although its presence associated only to the acute phase of ischemia and its immediate cessation after early and effective revascularization is anecdotal in the literature, with a consequent lack of evidence for further treatment. A clinical case in which early coronary intervention managed to achieve a cardioversion of atrial fibrillation to sinus rhythm during an acute myocardial infarction is reported. Subsequently, it is discussed the strategy that must be followed with regard to arrhythmia in a patient with good clinical outcome after the event.

  16. Preparing the way for coming area wide integrated pest management projects against the new world screwworm, Cochliomyia hominivorax, in MERCOSUR

    Energy Technology Data Exchange (ETDEWEB)

    Mastrangelo, Thiago; Fernandes, Thiago; Walder, Julio, E-mail: piaui@cena.usp.br [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil); Bezerra, Fernando [Instituto Federal de Educacao, Ciencia e Tecnologia do Sertao Pernambucano (IFSERTAO-PE), Petrolina, PE (Brazil)

    2011-07-01

    The New World Screwworm (NWS), Cochliomyia hominivorax, was eradicated from the USA, Central America to Panama, but in most tropical regions of Latin America, the NWS is still a serious threat to livestock, provoking estimated annual losses of US$ 1.8 billion in Brazil. Between January and May 2009, a pilot-project was performed at the Brazil-Uruguay border. As the results were positive, novel regional Area-Wide Integrated Pest Management projects are being planned. To set a mass-rearing center based in South America is strategic when considering long-term programs. In partnership with CENA/USP and the Biofactory MOSCAMED Brazil, a project to produce sterile NWS started on 2009. The project aimed to maintain a colony of a regional NWS strain, to develop a mass-rearing system and a sterilization protocol by X rays, and to study the sterility induction in regional strains. A colony was successfully established. The adults were kept in cages and fed on a diet (honey and spray dried egg). The larvae were reared in a medium made of spray dried blood, spray dried egg, milk, water, formalin and Ecogel. Egg hatch has been of 80 {+-} 10%. From F{sub 1} to F{sub 22}, the total amount of pupae produced was about 38 L ({approx} 315,400 pupae). The mean adult emergence and sex ratio were 86.7 {+-} 3% and 0.59 {+-} 0.08 respectively. The mean pupal weight was 47.1 {+-} 1.7 mg. The estimated X ray doses to induce 99% sterility in males and females were 43.7 Gy and 47.5 Gy, respectively. To produce 1.5 L of pupae, the current cost is about US$ 15.00. (author)

  17. Preparing the way for coming area wide integrated pest management projects against the new world screwworm, Cochliomyia hominivorax, in MERCOSUR

    International Nuclear Information System (INIS)

    The New World Screwworm (NWS), Cochliomyia hominivorax, was eradicated from the USA, Central America to Panama, but in most tropical regions of Latin America, the NWS is still a serious threat to livestock, provoking estimated annual losses of US$ 1.8 billion in Brazil. Between January and May 2009, a pilot-project was performed at the Brazil-Uruguay border. As the results were positive, novel regional Area-Wide Integrated Pest Management projects are being planned. To set a mass-rearing center based in South America is strategic when considering long-term programs. In partnership with CENA/USP and the Biofactory MOSCAMED Brazil, a project to produce sterile NWS started on 2009. The project aimed to maintain a colony of a regional NWS strain, to develop a mass-rearing system and a sterilization protocol by X rays, and to study the sterility induction in regional strains. A colony was successfully established. The adults were kept in cages and fed on a diet (honey and spray dried egg). The larvae were reared in a medium made of spray dried blood, spray dried egg, milk, water, formalin and Ecogel. Egg hatch has been of 80 ± 10%. From F1 to F22, the total amount of pupae produced was about 38 L (∼ 315,400 pupae). The mean adult emergence and sex ratio were 86.7 ± 3% and 0.59 ± 0.08 respectively. The mean pupal weight was 47.1 ± 1.7 mg. The estimated X ray doses to induce 99% sterility in males and females were 43.7 Gy and 47.5 Gy, respectively. To produce 1.5 L of pupae, the current cost is about US$ 15.00. (author)

  18. Adjuvant auricular electroacupuncture and autogenic training in rheumatoid arthritis: a randomized controlled trial

    DEFF Research Database (Denmark)

    Bernateck, M.; Becker, M.; Schwacke, C.;

    2008-01-01

    BACKGROUND: In contrast to psychological interventions the usefulness of acupuncture as an adjuvant therapy in rheumatoid arthritis (RA) has not yet been demonstrated. OBJECTIVE: The efficacy of auricular electroacupuncture (EA) was directly compared with autogenic training (AT). METHODS: Patients...

  19. Avaliação da colocação de protetores auriculares em grupos com e sem treinamento Evaluation of hearing-protector insertion in groups with and without training

    Directory of Open Access Journals (Sweden)

    Cláudia Giglio de Oliveira Gonçalves

    2009-06-01

    Full Text Available OBJETIVO: analisar a eficácia da colocação de diferentes protetores auriculares em sujeitos treinados e não-treinados e verificar a importância e a necessidade da realização de um treinamento para a colocação adequada do Equipamento de Proteção Individual auricular. MÉTODOS: investigou-se a atenuação de quatro modelos diferentes de protetores auriculares (inserção de espuma, inserção de silicone três flanges, inserção oliva e tipo concha por meio de duas estratégias: audiometria em campo livre e medidas com microfone sonda, com e sem protetor auricular para comparação e determinação da vedação de ruído. Avaliou-se dois grupos, Grupo 1, sujeitos que receberam treinamento e orientação em relação ao uso e colocação do EPI auricular (23 e o Grupo 2, sujeitos não-treinados (8 universitários que nunca utilizaram o EPI auricular. RESULTADOS: no grupo 1, as diferenças dos limiares auditivos sem e com protetor auricular avaliadas pelos dois métodos apresentaram, em geral, valores de atenuação superiores ao do grupo 2. O protetor auricular concha apresentou valores médios de atenuação superiores aos demais tipos; e o protetor auricular oliva apresentou valores menores. CONCLUSÃO: o treinamento quanto ao uso dos protetores auriculares é necessário e deve ser incluído nos Programa de Conservação Auditiva (PCA.PURPOSE: to analyze the effectiveness for inserting different hearing protectors in trained and non-trained subjects. METHODS: we investigated the attenuation for four models of hearing protectors (foam earplugs, three-flange silicone earplugs, olive end earplugs and shell earplugs by means of two strategies, namely, free-field audiometry and microphone probe measurements, with and without h. p. for comparison and determination of noise elimination. Two groups were evaluated: Group 1, with workers trained (23 in the use of hearing protectors, and Group 2, with non-trained ones (8. RESULTS: in group 1

  20. The Effects and Measures of Auricular Acupressure and Interactive Multimedia for Smoking Cessation in College Students

    OpenAIRE

    Mei-Ling Yeh; Pei-Lan Wang; Jaung-Geng Lin; Mei-Ling Chung

    2014-01-01

    The earlier one starts to smoke, the more likely it is that one’s tobacco use will increase. Either auricular acupressure or multimedia education could improve physiological health status and reduce smoking for young smokers. This study aimed to evaluate the effects of a 10-week auricular acupressure (AA) and interactive multimedia (IM) on smoking cessation in college smokers. A pre- and posttest control research design with two experiments (AA and IM) and one control was used. Thirty-two par...

  1. A feasibility study of auricular therapy and self-administered acupressure for insomnia following cancer treatment

    OpenAIRE

    Hughes, John Gareth; Towler, Penny; Storey, Lesley; Wheeler, Sara Louise; Molassiotis, Alex

    2015-01-01

    Introduction: Many cancer patients experience sleeping difficulties which can persist several years after the completion of cancer treatment. Previous research suggests that acupuncture, and variants of acupuncture (acupressure, auricular therapy) may be effective treatment options for sleep disturbance. However, current evidence is limited for cancer patients.Methods: Feasibility study with 3 arms. Seven cancer patients with insomnia randomised to receive either auricular therapy (attaching ...

  2. The effects of auricular acupuncture on weight reduction and feeding-related cytokines: a pilot study

    OpenAIRE

    Ito, Hisayuki; Yamada, Osamu; Kira, Yuji; Tanaka, Takeshi; Matsuoka, Rumiko

    2015-01-01

    Objective Auricular acupuncture is a common therapy used to control appetite; however, the underlying mechanism(s) of action is unclear. The present study examined changes in feeding behaviour and in the levels of several appetite-related hormones in response to auricular acupuncture, and attempted to identify the mechanism(s) by which this traditional medical treatment exerts its effects. Methods Ten healthy adult volunteers (nine female and one male) were recruited by the KOSAI Oriental Hea...

  3. Combining regenerative medicine strategies to provide durable reconstructive options: auricular cartilage tissue engineering

    OpenAIRE

    Jessop, Zita M.; Javed, Muhammad; Otto, Iris A.; Combellack, Emman J.; Morgan, Siân; Breugem, Corstiaan C; Archer, Charles W.; Khan, Ilyas M.; Lineaweaver, William C.; Kon, Moshe; Malda, Jos; Whitaker, Iain S

    2016-01-01

    Recent advances in regenerative medicine place us in a unique position to improve the quality of engineered tissue. We use auricular cartilage as an exemplar to illustrate how the use of tissue-specific adult stem cells, assembly through additive manufacturing and improved understanding of postnatal tissue maturation will allow us to more accurately replicate native tissue anisotropy. This review highlights the limitations of autologous auricular reconstruction, including donor site morbidity...

  4. Bilateral recurrent auricular pseudocyst: Importance of fine-needle aspiration cytology and lactate dehydrogenase estimation

    Directory of Open Access Journals (Sweden)

    Kalyan Khan

    2013-01-01

    Full Text Available Auricular pseudocyst or Idiopathic cystic chondromalacia is a rare, benign condition characterized by a focal noninflammatory cystic swelling on the pinna, occurring usually in young male patients. Bilaterality and recurrence have been reported rarely. We report a case of bilateral, recurrent auricular pseudocyst in a young male patient, where fine needle aspiration cytology coupled with fluid lactate dehydrogenase level estimation was diagnostic. Repeated surgery was avoided and conservative treatment was proved to be effective.

  5. [The Usage of Auricular Acupressure in Clinical Nursing and Evidence-Based Research].

    Science.gov (United States)

    Cheng, Jui-Fen; Lo, Chyi; Tzeng, Ya-Ling

    2015-12-01

    Auricular acupressure is a non-invasive physiotherapy that was developed based on the traditional Chinese meridian theory. Because it is non-invasive, simple to implement, and easy to learn, and because it presents minimal side effects and may be executed independently, this therapy may be used as an alternative or auxiliary approach to symptom management as well as to self-care. The increasing support for auricular acupressure from evidence-based research in Taiwan and elsewhere offers the opportunity to include auricular acupressure as a treatment option in evidence-based nursing interventions. Because nursing education in Taiwan is guided by Western medical concepts and principles, most nurses are not familiar with auricular acupressure, which is derived from traditional Chinese medicine. Therefore, this article not only systemically introduces the definition and theoretical basis of auricular acupressure but also includes the principles and application-related knowledge. Furthermore, this article analyzes the common problems encountered in auricular acupressure research in order to improve the familiarity of nurses with this therapy, to provide references for clinical application, and to provide a basis for designing new evidence-based nursing research efforts. PMID:26645441

  6. Efficacy of Auricular Therapy for Pain Management: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Chao Hsing Yeh

    2014-01-01

    Full Text Available Objective. The objective of this systematic review and meta-analysis was to assess the efficacy of auricular therapy by including a sham therapy control group. Methods. Relevant, randomized clinical trials (RCTs were identified by searching medical related databases from, depending on journal, 1900 (at the earliest to 1994 (at the latest through May 2013. The outcome measure was a pain intensity score. Results. Twenty-two RCTs were identified and 13 RCTs were included for meta-analysis. In these studies, auricular therapy provided significant pain relief when compared to a sham or control group. The overall standardized mean differences (SMD was 1.59 (95% CI [−2.36, −0.82] (13 trials, total subject numbers = 806, indicating that, on average, the mean decrease in pain score for auricular therapy group was 1.59 standard deviations greater than the mean decrease for the sham control. In terms of the efficacy of the different treatment methods, auricular acupressure boasts the largest strength of evidence for pain relief, followed by auricular acupuncture. Electroacupuncture stimulation did not show significant evidence for efficacy, which may be due to the small sample size (i.e., only 19 subjects were included. Conclusion. Further large-scale RCTs are needed to determine the efficacy of auricular therapy for pain.

  7. Non-surgical Management of Congenital Auricular Deformities

    Science.gov (United States)

    Mohammadi, Ali Akbar; Imani, Mohammad Taghi; Kardeh, Sina; Karami, Mehrab Mohammad; Kherad, Masoomeh

    2016-01-01

    BACKGROUND Unlike congenital auricular malformations which are identified by underdevelopment of dermal and cartilaginous tissues, deformed ears are less sever congenital anomalies characterized only by a misshaped pinna structure and can be improved with acceptable cosmetic results and minimal cost through ear molding if treated in early neonatal period. In this study, authors present the first report of using splinting techniques for treatment of deformational auricular anomalies in Iranian children. METHODS Our case load consisted of a series of 29 patients (Male=16, Female=13) who were referred to Plastic Surgery Unit of Shiraz University of Medical Sciences from September 2011 to December 2014. Children aged more than 6 moths were excluded. Twenty-nine children affected by various deformities including prominent ears (n=11), lop ears (n=8) and constricted ears (n=10) were treated by splintage as a nonsurgical technique. The mean time of treatment was 13.33±2 weeks. RESULTS Eight (27.6%) patients did not complete the treatment. Splinting resulted in excellent or satisfactory results in 12 (57.14%) of treated cases. No improvement was observed at the end of the molding treatment in 9 patients. No complication was observed during the treatment in any of the patients. CONCLUSION The nonsurgical molding can be used as an effective approach for achieving natural outcomes and correcting cosmetic abnormalities. Rate of satisfaction is dependent on type of deformity, the neonatal age in which treatment started and also parents’ adherence to treatment methods and principals. Concerning the low rate of complications and high satisfactory results the method can be used instead of surgery in appropriate cases.

  8. Acupuncture: a potential modality for the treatment of auricular pruritus in Ramsay Hunt Syndrome with multiple cranial nerve lesions.

    Science.gov (United States)

    Liu, Lan Ying; Wang, He Sheng; Sun, Jian Hua

    2015-03-01

    Auricular pruritus coexisted with multiple cranial nerve lesions in Ramsay Hunt syndrome has been rarely reported in the literature especially its treatment. However, auricular pruritus cannot be better improved along with the improvement of multiple cranial nerve lesions. We tried to solve the problem with acupuncture and got experience from it. The following 2 cases of Ramsay Hunt syndrome show a potential modality for the treatment of auricular pruritus with acupuncture.

  9. Refinamientos en la reconstrucción del tercio superior auricular con la técnica de Davis: Estudio anatómico y serie clínica Refinements on reconstruction of auricular upper pole defects with Davi's technique: Anatomical study and clinical series

    OpenAIRE

    S. Llanos; Bravo, M.; B. Dagnino; Guerra, C.; J.L. Piñeros; W. Calderón

    2009-01-01

    Los defectos del tercio superior auricular son un desafío reconstructivo. Están descritas diferentes técnicas quirúrgicas para este fin con resultados a veces desfavorables Realizamos un estudio anatómico en cadáveres frescos que mostró la presencia constante de un pedículo neurovascular que penetra la raíz del hélix. Mostramos la localización y los diámetros de los vasos. Basándonos en este estudio anatómico, presentamos una serie de 10 casos consecutivos tratados por el autor principal. Ana...

  10. Efeitos do ultra-som de baixa intensidade na veia auricular de coelhos Effects of low intensity ultrasound in the auricular vein of rabbits

    Directory of Open Access Journals (Sweden)

    Marcelo Araújo

    2003-01-01

    Full Text Available OBJETIVO: Estudar a ação do ultra-som na veia auricular de coelhos. MÉTODOS: Vinte coelhos foram divididos em dois grupos de dez animais diferindo com relação ao local da aplicação, do ultra-som, o modo e o intervalo de tempo para a análise histopatológica (3 e 7 dias. Os animais foram submetidos à aplicação de ultra-som contínuo e pulsado em dois segmentos venosos da orelha previamente determinados. Cada animal foi o seu próprio controle. Empregou-se a freqüência de 3MHz, intensidade de 3W/cm² nos ciclos pulsado e contínuo por 10 minutos, de forma estacionária. O grupo I foi submetido a eutanásia após 3 dias e o grupo II em 7 dias contemplando a fase aguda do processo inflamatório. Empregou-se o teste exato de Fisher e o teste de Mc Nemar para análise estatística. RESULTADOS: Obteve-se trombose venosa e aumento de linfócitos de forma significativa (p= 0,032 nos grupos tratados com o modo contínuo. O modo pulsado não provocou efeitos deletérios. Outros achados foram congestão, edema, hemorragia e lesão da parede vascular. CONCLUSÕES: O ultra-som pulsado não provoca qualquer alteração na parede vascular nas condições do experimento.O ultra-som contínuo induz a trombose venosa e aumento dos linfócitos de forma significativa.PURPOSE: The purpose of this experimental work was evaluate the effects of low intensity in the auricular vein of rabbits. METHODS: Twenty rabbits were divided in two groups of ten animals. The groups differed about the place where the continuous and pulsed ultrasound were applied and the period that the material was collected for the morphologic examination (3 and 7 days. Acoustic coupling gel was used on marginal ear vein, each animal underwent continuous and pulsed ultrasound treatment, in segments previously marked with indelible ink. Each animal provided its own control. Ultrasound was used in the frequency of 3MHz, intensity of 3W/cm² in the pulsed and continuous modes during 10min

  11. Use of Auricular Acupressure to Improve the Quality of Life in Diabetic Patients with Chronic Kidney Diseases: A Prospective Randomized Controlled Trial

    OpenAIRE

    Shaoqing Wang; Zhaohui Chen; Ping Fu; Li Zang; Li Wang; Xi Zhai; Fang Gao; Aijing Huang; Yao Zhang

    2014-01-01

    Background. Diabetic patients with chronic kidney disease (CKD) suffer from low quality of life (QOL). We aim to assess the effectiveness of auricular acupressure for QOL improvement in these patients. Materials and Methods. Sixty-two participants were randomly assigned to an auricular or a control arm in a randomized controlled trial. Participants in the auricular arm were instructed to perform auricular acupressure 3–5 times per day for 3 months, when they were receiving conventional treatm...

  12. Eficácia da escolha do protetor auditivo pequeno, médio e grande em programa de conservação auditiva Efficacy in the choice of small, medium or large auricular protector under auditive conservation program

    Directory of Open Access Journals (Sweden)

    Marleide Aparecida Griggio Rodrigues

    2006-12-01

    Full Text Available OBJETIVO: verificar a eficácia da escolha do protetor auditivo por tamanhos Pequeno, Médio, Grande em um programa de conservação auditiva. MÉTODO: fizeram parte do estudo 30 indivíduos com audição normal previamente avaliados, de 18 a 45 anos de idade, sendo 15 do gênero feminino e 15 do gênero masculino, de Indústria Moveleira. Os sujeitos foram submetidos à avaliação audiológica convencional, audiometria em campo livre sem protetor auricular de inserção, com protetor tamanho universal e com tamanho adequado a cada indivíduo. Para análise estatística foi aplicado teste T Paramétrico para análise das diferenças. RESULTADOS: O teste T Paramétrico pareado, mostrou significância, na comparação dos protetores auriculares na freqüência de 4KHz. CONCLUSÃO: os resultados mostraram eficácia dos protetores auriculares pequeno e grande sobre os protetores tamanho universal em um programa de conservação auditiva.PURPOSE: to check the efficacy in the choice of small, medium or large auricular protector under auditive conservation program. METHODS: 30 individuals, between 18 to 45-year old, with normal hearing, were part of the study previously evaluated: 15 women and 15 men, all working in a furniture industry. The individuals were submitted to the conventional audiological evaluation, audiometry in free field without auricular insertion protector, with universal size protector and with size adequate to each individual. For statistical analysis we used Parametric T test for analyzing the differences. RESULTS: the Parametric T test showed significance, during the comparison of the auricular protectors in the frequency of 4KHz. CONCLUSION: these results demonstrate efficacy in choice of small, medium or large auditive protector, under auditive conservation program.

  13. Engineered cartilage covered ear implants for auricular cartilage reconstruction.

    Science.gov (United States)

    Lee, Sang Jin; Broda, Christopher; Atala, Anthony; Yoo, James J

    2011-02-14

    Cartilage tissues are often required for auricular tissue reconstruction. Currently, alloplastic ear-shaped medical implants composed of silicon and polyethylene are being used clinically. However, the use of these implants is often associated with complications, including inflammation, infection, erosion, and dislodgement. To overcome these limitations, we propose a system in which tissue-engineered cartilage serves as a shell that entirely covers the alloplastic implants. This study investigated whether cartilage tissue, engineered with chondrocytes and a fibrin hydrogel, would provide adequate coverage of a commercially used medical implant. To demonstrate the in vivo stability of cell-fibrin constructs, we tested variations of fibrinogen and thrombin concentration as well as cell density. After implantation, the retrieved engineered cartilage tissue was evaluated by histo- and immunohistochemical, biochemical, and mechanical analyses. Histomorphological evaluations consistently showed cartilage formation over the medical implants with the maintenance of dimensional stability. An initial cell density was determined that is critical for the production of matrix components such as glycosaminoglycans (GAG), elastin, type II collagen, and for mechanical strength. This study shows that engineered cartilage tissues are able to serve as a shell that entirely covers the medical implant, which may minimize the morbidity associated with implant dislodgement. PMID:21182236

  14. Clinical aspects and dynamics of auricular parasitosis in Gir cattle

    Directory of Open Access Journals (Sweden)

    Patrícia V.B. Leite

    2013-03-01

    Full Text Available We evaluated the dynamics of ear infestations caused by Rhabditis spp. and Raillietia spp., which were correlated with animal age, intensity of clinical signs and climate factors. Sixty-four Gir cattle were distributed into three groups: GA - 23 calves with 4 to 6 months of age; GB - 18 calves with 7 to 12 months of age; and GC - 23 heifers with 13 to 33 months of age. Five samplings, defined as S1, S2, S3, S4 and S5 were performed every three months from August 2008 to August 2009. The ear secretion was collected using the auricular washing method for the right ear and a swab for the left ear. A clinical assessment of the animals was performed, and they were classified according to the presence and severity of otitis. The highest relative frequency of rhabditosis was 52.2% in GC at the last sampling. In the first sampling, 42.2% of the animals were infested by Raillietia spp. The older cattle were more susceptible to infestations by both parasites. No correlation of Rhabditis spp. and Raillietia spp. parasitism with climate factors was found. The results showed that both parasites could infest Gir cattle, and in most cases, there was no co-infestation. Only older animals parasitized by the nematode showed clinical signs of the disease.

  15. Protocolo de tratamiento de cicatrices queloides en el pabellón auricular del Hospital General Dr. Manuel Gea González Treatment protocol of auricular keloid scars in the General Hospital Dr. Manuel Gea González

    Directory of Open Access Journals (Sweden)

    C. Gutiérrez Gómez

    2012-03-01

    Full Text Available Las cicatrices queloideas son una de las patologías de más difícil tratamiento por el alto porcentaje de recidivas que presentan, hasta un 100 % en tratamientos únicos y un 50 % en tratamientos combinados. El pabellón auricular es un blanco frecuente de esta patología. Presentamos el protocolo de tratamiento empleado en nuestro hospital en los últimos 6 años con terapia combinada en 51 pacientes y 64 pabellones auriculares afectados por queloides. Aplicamos de forma preoperatoria 3 dosis de triamcinolona o betametasona intralesional, con diferencia de 4 a 6 semanas entre dosis y 4 semanas después de la última dosis, realizamos resección de la cicatriz dejando piel suficiente para el cierre sin tensión. En los pacientes que presentaban antecedente de resección quirúrgica se añadió al tratamiento el uso de colchicina, comenzando el día de la cirugía y manteniéndolo durante 8 semanas, a dosis de 1 mg. al día, con control de pruebas de función hepática pre y postratamiento. En el 74.5 % de los casos la cicatriz queloide fue unilateral; el 56.8 % de los pacientes fueron mujeres; las edades fluctuaron entre los 8 y los 61 años con una media de 24 años de edad. En el 65 % de los casos el queloide se presentó en el pabellón auricular derecho y en cuanto a su localización dentro del mismo, el 42 % se presentó en el lóbulo. La causa en el 56 % de los casos fue por perforación. El 18.6 % de las cicatrices tratadas cedieron con la infiltración intralesional; de las 48 cicatrices que recibieron tratamiento quirúrgico, hubo recidiva en el 12.5 % (6 cicatrices, con un seguimiento de entre 8 meses a 6 años.Keloid scars are one of the most difficult pathologies to treat because its high rate of recurrence, from 100 % with single treatment to 50 % with combined therapy. The auricle is a frequent localization of keloids. We report our experience in the last 6 years with combined therapy in 51 patients and 64 auricles with keloid

  16. Influence of Auricular Plaster Therapy on Sleeping Structure in OSAS Patients

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-hong; XIAO Lan-ying; WANG Bao-fa; YUAN Ya-dong; PAN Wen-sen; SHI Yu-zhen

    2009-01-01

    To evaluate the therapeutic effects of auricular plaster therapy for obstructive sleep apnea syndrome (OSAS) and the influence on sleeping structure. Methods: 45 OSAS patients were randomly divided into a treatment group of 30 cases and a control group of 15 cases for comparison of the changes in parameters of respiration and sleep at night. Results: The auricular plaster therapy significantly improved the hypoventilation index, respiratory disturbance index and other respiratory parameters as well as the sleeping parameters such as the time and rate of sleep at stage Ⅰ and Ⅱ, and the waking time and rate.Conclusion: Auricular plaster therapy may show good therapeutic effects for OSAS, and with the advantages of low cost and less side effects.

  17. Efficacy Observation on Acupuncture Combined with Auricular Point Sticking Treatment for Primary Dysmenorrhea

    Institute of Scientific and Technical Information of China (English)

    Liu Xiao-xia; Wang Xi

    2013-01-01

    Objective:To observe the clinical efficacy of acupuncture combined with auricular point sticking treatment for primary dysmenorrhea.Methods:Sixty-eight patients with primary dysmenorrhea were randomly divided into two groups,and 35 cases in the treatment group were treated by acupuncture combined with auricular point sticking,while 33 cases in the control group were only treated by acupuncture.The treatments for the patients in both groups began from one week before their menstruation and continued till the menstruation came.And the efficacy was observed after treatments of three consecutive menstrual cycles.Results:The total effective rate was 94.2% in the treatment group,versus 84.8% in the control group,and the difference was statistically significant (P<0.05).Conclusion:Acupuncture combined with auricular point sticking treatment for primary dysmenorrhea is more effective than simple acupuncture.

  18. Effect of self-administered auricular acupressure on smoking cessation --a pilot study

    Directory of Open Access Journals (Sweden)

    Leung Lawrence

    2012-02-01

    Full Text Available Abstract Background Tobacco smoking is still a worldwide health risk. Current pharmacotherapies have at best, a success rate of no more than 50%. Auricular (ear acupressure has been purported to be beneficial in achieving smoking cessation in some studies, while in others has been deemed insignificant. We hereby describe the protocol for a three-arm randomised controlled trial to examine the possible benefits of self-administered acupressure for smoking cessation. Methods Sixty consenting participants with confirmed habit of tobacco smoking will be recruited and randomized into three arms to receive either auricular acupressure at five true acupoints (NADA protocol, auricular acupressure at five sham points, or no auricular acupressure at all. Participants having auricular acupressure will exert firm pressure to each acupoint bilaterally via the bead in the attached plasters whenever they feel the urge to smoke. The treatment phase will last for six weeks during which all participants will be assessed weekly to review their smoking log, state of abstinence, end-exhalation carbon monoxide levels and possible adverse effects including withdrawal reactions and stress levels. At any time, a successful quit date will be defined with continuous abstinence for the following consecutive 7 days. From then on, participants will be evaluated individually for continuous abstinence rate (CAR, end-exhalation carbon monoxide levels and adverse effects of stress and withdrawal at specified intervals up to 26 weeks. Expectancy of treatment will be assessed with a four-item Borkovec and Nau self-assessment credibility scale during and after intervention. Discussion We incorporate validated outcome measures of smoking cessation into our randomised controlled trial design with the objectives to evaluate the feasibility and possible benefits of self-administered auricular acupressure as a non-invasive alternative to pharmacotherapy for smoking cessation. Trial

  19. Growth factor stimulation improves the structure and properties of scaffold-free engineered auricular cartilage constructs.

    Directory of Open Access Journals (Sweden)

    Renata G Rosa

    Full Text Available The reconstruction of the external ear to correct congenital deformities or repair following trauma remains a significant challenge in reconstructive surgery. Previously, we have developed a novel approach to create scaffold-free, tissue engineering elastic cartilage constructs directly from a small population of donor cells. Although the developed constructs appeared to adopt the structural appearance of native auricular cartilage, the constructs displayed limited expression and poor localization of elastin. In the present study, the effect of growth factor supplementation (insulin, IGF-1, or TGF-β1 was investigated to stimulate elastogenesis as well as to improve overall tissue formation. Using rabbit auricular chondrocytes, bioreactor-cultivated constructs supplemented with either insulin or IGF-1 displayed increased deposition of cartilaginous ECM, improved mechanical properties, and thicknesses comparable to native auricular cartilage after 4 weeks of growth. Similarly, growth factor supplementation resulted in increased expression and improved localization of elastin, primarily restricted within the cartilaginous region of the tissue construct. Additional studies were conducted to determine whether scaffold-free engineered auricular cartilage constructs could be developed in the 3D shape of the external ear. Isolated auricular chondrocytes were grown in rapid-prototyped tissue culture molds with additional insulin or IGF-1 supplementation during bioreactor cultivation. Using this approach, the developed tissue constructs were flexible and had a 3D shape in very good agreement to the culture mold (average error <400 µm. While scaffold-free, engineered auricular cartilage constructs can be created with both the appropriate tissue structure and 3D shape of the external ear, future studies will be aimed assessing potential changes in construct shape and properties after subcutaneous implantation.

  20. OBSERVATION ON THE THERAPEUTIC EFFECT OF AURICULAR PLASTER FOR TREATMENT OF 135 CASES OF MOTION SICKNESS

    Institute of Scientific and Technical Information of China (English)

    饶忠东; 温明; 等

    2002-01-01

    In he present paper,the therapeutic effects of aurcular plaster(otopoint-pellet pressing therapy)and Western medicine(Dramamine)were compared in the treatment of 200 cases of motion sickness who were randomly divided into auricular plaster group(n=135) and western medicine(control)group(n=65).Results indicated that the markedly effective rates and total effective rates of auricular plaster group and control group were 51.1% and 23.1%,94.1%and 81.6% respectively,and the therapeutic effect of the former group was significantly superior th that of the control group(P<0.01).

  1. Improved Construction of Auricular Prosthesis by Digital Technologies.

    Science.gov (United States)

    Nuseir, Amjad; Hatamleh, Muhanad; Watson, Jason; Al-Wahadni, Ahed M; Alzoubi, Firas; Murad, Mohammed

    2015-09-01

    Implant-retained auricular prostheses are a successful prosthetic treatment option for patients who are missing their ear(s) due to trauma, oncology, or birth defects. The prosthetic ear is aesthetically pleasing, composed of natural looking anatomical contours, shape, and texture along with good color that blends with surrounding existing skin. These outcomes can be optimized by the integration of digital technologies in the construction process. This report describes a sequential process of reconstructing a missing left ear by digital technologies. Two implants were planned for placement in the left mastoid region utilizing specialist biomedical software (Materialise, Belgium). The implant positions were determined underneath the thickest portion (of anti-helix area) left ear that is virtually simulated by means of mirror imaging of the right ear. A surgical stent recording the implant positions was constructed and used in implant fixtures placement. Implants were left for eight weeks, after which they were loaded with abutments and an irreversible silicone impression was taken to record their positions. The right existing ear was virtually segmented using the patient CT scan and then mirror imaged to produce a left ear, which was then printed using 3D printer (Z Corp, USA). The left ear was then duplicated in wax which was fitted over the defect side. Then, it was conventionally flasked. Skin color was digitalized using spectromatch skin color system (London, UK). The resultant silicone color was mixed as prescribed and then packed into the mold. The silicone was cured conventionally. Ear was trimmed and fitted and there was no need for any extrinsic coloring. The prosthetic ear was an exact match to the existing right ear in shape, skin color, and orientation due to the great advantages of technologies employed. Additionally, these technologies saved time and provided a base for reproducible results regardless of operator. PMID:26221855

  2. Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial.

    Science.gov (United States)

    Yan, Cui-Na; Yao, Wei-Guo; Bao, Yi-Jie; Shi, Xiao-Jing; Yu, Hui; Yin, Pei-Hao; Liu, Gui-Zhen

    2015-01-01

    Background. Uremic pruritus (UP) is a common symptom in patients undergoing maintenance hemodialysis for end-stage renal disease (ESRD). Objective. To determine the clinical efficacy of auricular acupressure therapy on pruritus in hemodialysis patients and to explore possible underlying mechanisms. Methods. Patients receiving maintenance hemodialysis at a referral medical center were recruited and assigned to intervention (n = 32) and control (n = 30) groups. The intervention group underwent auricular acupressure treatment three times a week for six weeks. Auricular acupressure was not applied to patients in the control group. However, tape without Vaccaria seeds was applied to the same six auricular acupoints as the intervention group. Pruritus scores were assessed using VAS scores, and enzyme-linked immunosorbent assays (ELISA) were used to measure levels of other possible contributory biochemical factors. Results. There was a significant difference in mean VAS scores between the postintervention and control groups during follow-up (3.844 ± 1.687 versus 5.567 ± 2.285, F = 22.32, P acupressure may be a useful treatment in the multidisciplinary management of UP in ESRD patients. PMID:26495017

  3. Long-term quality of life assessment in patients with auricular prostheses

    NARCIS (Netherlands)

    Kievit, H.; Verhage-Damen, G.W.; Ingels, K.J.A.O.; Mylanus, E.A.M.; Hol, M.K.S.

    2013-01-01

    OBJECTIVE: To investigate the quality of life of people with an auricular prosthesis. METHODS: A retrospective case series study was conducted. Quality of life was evaluated by an open-ended question form and 3 questionnaires: the Glasgow Benefit Inventory, the Rosenberg Self-Esteem scale, and the s

  4. Forty Cases of Insomnia Treated by Multi-output Electric Pulsation and Auricular Plaster Therapy

    Institute of Scientific and Technical Information of China (English)

    Liu Weizhe

    2007-01-01

    @@ The writer has treated 40 cases of insomnia by the method of multi-output electric pulsation in combination with auricular plaster therapy (with a seed of Vaccariae segetalis 王不留行 taped tightly to a particular ear point and pressed) and received satisfactory therapeutic effects. A report follows.

  5. A Novel Biodegradable Polyurethane Matrix for Auricular Cartilage Repair: An In Vitro and In Vivo Study.

    Science.gov (United States)

    Iyer, Kartik; Dearman, Bronwyn L; Wagstaff, Marcus J D; Greenwood, John E

    2016-01-01

    Auricular reconstruction poses a challenge for reconstructive and burns surgeons. Techniques involving cartilage tissue engineering have shown potential in recent years. A biodegradable polyurethane matrix developed for dermal reconstruction offers an alternative to autologous, allogeneic, or xenogeneic biologicals for cartilage reconstruction. This study assesses such a polyurethane matrix for this indication in vivo and in vitro. To evaluate intrinsic cartilage repair, three pigs underwent auricular surgery to create excisional cartilage ± perichondrial defects, measuring 2 × 3 cm in each ear, into which acellular polyurethane matrices were implanted. Biopsies were taken at day 28 for histological assessment. Porcine chondrocytes ± perichondrocytes were cultured and seeded in vitro onto 1 × 1 cm polyurethane scaffolds. The total culture period was 42 days; confocal, histological, and immunohistochemical analyses of scaffold cultures were performed on days 14, 28, and 42. In vivo, the polyurethane matrices integrated with granulation tissue filling all biopsy samples. Minimal neocartilage invasion was observed marginally on some samples. Tissue composition was identical between ears whether perichondrium was left intact, or not. In vitro, the polyurethane matrix was biocompatible with chondrocytes ± perichondrocytes and supported production of extracellular matrix and Type II collagen. No difference was observed between chondrocyte culture alone and chondrocyte/perichondrocyte scaffold coculture. The polyurethane matrix successfully integrated into the auricular defect and was a suitable scaffold in vitro for cartilage tissue engineering, demonstrating its potential application in auricular reconstruction. PMID:26284639

  6. Treatment of 20 Infants with Night Crying by Tuina and Auricular Application

    Institute of Scientific and Technical Information of China (English)

    肖莲英

    2010-01-01

    Night crying is a condition that infants under one year old often cry at night, or at regular times, sometimes throughout the entire night, but acting normal during daytime. We treated 20 cases by tuina and auricular application. It is reported as follows.

  7. Psychosocial and Quality of Life Outcomes of Prosthetic Auricular Rehabilitation with CAD/CAM Technology

    Directory of Open Access Journals (Sweden)

    Chi Keung Tam

    2014-01-01

    Full Text Available Introduction. The psychosocial and quality of life (QoL of patients with deformed or missing ears are frequently compromised. The aim of this study is to develop innovative techniques using CAD/CAM technology in prosthetic auricular rehabilitation and provide improvement in the treatment outcomes, including their psychology and QoL. Methods. This is a preliminary clinical cohort study. Six patients requesting for auricular reconstruction were recruited and rehabilitated with implant-supported prosthesis using CAD/CAM technology. Different treatment outcomes including QoL and psychological changes were assessed at different time points. Results. A significant reduction in severity of depressive symptoms (P=0.038 and an improving trend of satisfaction with life were found at 1 year postoperatively when compared with the preoperative findings. The domain scores in ‘‘Body image’’, ‘‘Family/friends/strangers’’, and ‘‘Mood’’ were also significantly higher (P<0.05 at 1 year postoperatively than 1 week postoperatively. However, only 50% of the patients wear their auricular prosthesis regularly. Conclusion. This preliminary study has confirmed that implant-supported auricular prosthesis could induce improvement in the psychology and QoL with statistically significant differences in the domains of the body image, social interaction, and mood. Our present findings can inform research design and hypotheses generation of future studies.

  8. Psychosocial and Quality of Life Outcomes of Prosthetic Auricular Rehabilitation with CAD/CAM Technology

    Science.gov (United States)

    Tam, Chi Keung; McGrath, Colman Patrick; Ho, Samuel Mun Yin; Pow, Edmond Ho Nang; Luk, Henry Wai Kuen; Cheung, Lim Kwong

    2014-01-01

    Introduction. The psychosocial and quality of life (QoL) of patients with deformed or missing ears are frequently compromised. The aim of this study is to develop innovative techniques using CAD/CAM technology in prosthetic auricular rehabilitation and provide improvement in the treatment outcomes, including their psychology and QoL. Methods. This is a preliminary clinical cohort study. Six patients requesting for auricular reconstruction were recruited and rehabilitated with implant-supported prosthesis using CAD/CAM technology. Different treatment outcomes including QoL and psychological changes were assessed at different time points. Results. A significant reduction in severity of depressive symptoms (P = 0.038) and an improving trend of satisfaction with life were found at 1 year postoperatively when compared with the preoperative findings. The domain scores in ‘‘Body image”, ‘‘Family/friends/strangers”, and ‘‘Mood” were also significantly higher (P < 0.05) at 1 year postoperatively than 1 week postoperatively. However, only 50% of the patients wear their auricular prosthesis regularly. Conclusion. This preliminary study has confirmed that implant-supported auricular prosthesis could induce improvement in the psychology and QoL with statistically significant differences in the domains of the body image, social interaction, and mood. Our present findings can inform research design and hypotheses generation of future studies. PMID:24799904

  9. Treatment of 56 Cases of Women with Post-adolescent Acne by Auricular Point Sticking Method

    Institute of Scientific and Technical Information of China (English)

    DING Min; JIANG Ya-qiu; CUI Xue-jun

    2008-01-01

    @@ Acne is a common disorder in adolescence. However, more and more patients are over 25 years old. This type of acne is recurrent, so it is called post-adolescence acne. The author treated 56 cases of women with post-adolescence acne by auricular point sticking method, and obtained excellent results. It is reported as follows.

  10. Fifty-Six Cases of Acne Treated by Auricular Needle-Embedding

    Institute of Scientific and Technical Information of China (English)

    侯慧先; 吴童

    2002-01-01

    @@ Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding with satisfactory therapeutic results as reported in the following.

  11. He-Ne Laser Auricular Irradiation Plus Body Acupuncture for Treatment of Acne Vulgaris in 36 Cases

    Institute of Scientific and Technical Information of China (English)

    Sun Lihong

    2006-01-01

    In order to observe the therapeutic effects of He-Ne laser auricular irradiation plus body acupuncture for acne vulgaris, 68 cases of acne vulgaris were randomly divided into a treatment group of 36 cases treated with He-Ne laser auricular irradiation plus body acupuncture, and a control group of 32 cases treated with body acupuncture only. The results showed that the cure rate was 77.8% in the treatment group and 46.9% in the control group (P<0.05), indicating that He-Ne laser auricular irradiation plus body acupuncture may exhibit better effects for acne vulgaris.

  12. Effectiveness of medication / auricular therapy / phyto-therapy combination in the treatment of hypertensive patients

    Directory of Open Access Journals (Sweden)

    José Ramón Martínez Pérez

    2015-10-01

    Full Text Available Background: hypertension is one of the main cardiovascular risk factors, so its control improves the life expectancy of patients.Objective: to assess the effects of a treatment combining medication with auricular therapy and phyto-therapy in hypertensive patients assisted at the health area of ”Romárico Oro” Polyclinic, in Puerto Padre, Las Tunas province.Methods: an intervention study was carried out in 68 hypertensive patients of the health area of “Romárico Oro” Polyclinic in Puerto Padre from April, 2013 to April, 2014. The patients were distributed at random into two equal groups; the first received medication combined with auricular therapy and phyto-therapy, while the second one received only medication. The statistical analysis was done by means of Statistic system, t-student and Chi-Square tests were used and p< or =0.05 was considered as level of statistical significance.Results: by the end of the intervention, 73, 53% of the patients of the group with the combination of drug treatment and auricular therapy and phyto-therapy were controlled. In this group, the diastolic filling pressure diminished to 2, 2 mm Hg and the systolic gradient to 3, 66 mm, regarding the group treated only with drugs. Only one patient, representing the 2, 94% showed adverse reaction to the natural and traditional treatment.Conclusions: the combination of medication with auricular therapy and phyto-therapy proved to be effective, corroborated by a significant decrease of quantity of crisis, diastolic and systolic filling pressure values and increase of number of patients with their disease controlled; the report of only one complication shows the innocuousness of the auricular therapy and phyto-therapy treatment.

  13. Auricular Acupressure Combined with an Internet-Based Intervention or Alone for Primary Dysmenorrhea: A Control Study

    OpenAIRE

    Mei-Ling Yeh; Yu-Ling Hung; Hsing-Hsia Chen; Jaung-Geng Lin; Yu-Jen Wang

    2013-01-01

    Background. Primary dysmenorrhea is prevalent in adolescents and young women. Menstrual pain and distress causes poor school performance and physiological damage. Auricular acupressure can be used to treat these symptoms, and Internet-based systems are a flexible way of communicating and delivering the relevant information. Objective. This study investigates the effects of auricular acupressure (AA) alone and combined with an interactive Internet-based (II) intervention for the management of ...

  14. Acupuncture and Auricular Acupressure in Relieving Menopausal Hot Flashes of Bilaterally Ovariectomized Chinese Women: A Randomized Controlled Trial

    OpenAIRE

    Jue Zhou; Fan Qu; Xisheng Sang; Xiaotong Wang; Rui Nan

    2011-01-01

    The objective of this study is to explore the effects of acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an acupuncture and auricular acupressure group (n = 21) and a hormone replacement therapy (HRT) group (Tibolone, n = 25). Each patient was given a standard daily log and was required to record the frequency and severity of ...

  15. Effect of Auricular Acupressure on Peri- and Early Postmenopausal Women with Anxiety: A Double-Blinded, Randomized, and Controlled Pilot Study

    Directory of Open Access Journals (Sweden)

    Ching-Ling Kao

    2012-01-01

    Full Text Available We tested effects of auricular acupressure on peri- and early postmenopausal women with anxiety (PPWA. Fifty PPWA were randomly assigned to the auricular acupressure group (AG or the sham group (SG. After 3 meals and before sleep every day for 4 weeks, the AG received auricular acupressure on the bilateral ear shenmen and subcortex points for 3 min per point on alternating ears. The SG received sham auricular acupressure. The Alprazolam was reduced from 0.5 mg/day at baseline to 0.3 mg/day 4 weeks after auricular acupressure (4 W in the AG (P.05. The Zolpidem was reduced from 3.0 mg/day at baseline to 1.5 mg/day at 4 W (P.05, thus, significant tapering medication, suggesting auricular acupressure is helpful to PPWA.

  16. Auricular Acupressure Combined with an Internet-Based Intervention or Alone for Primary Dysmenorrhea: A Control Study

    Directory of Open Access Journals (Sweden)

    Mei-Ling Yeh

    2013-01-01

    Full Text Available Background. Primary dysmenorrhea is prevalent in adolescents and young women. Menstrual pain and distress causes poor school performance and physiological damage. Auricular acupressure can be used to treat these symptoms, and Internet-based systems are a flexible way of communicating and delivering the relevant information. Objective. This study investigates the effects of auricular acupressure (AA alone and combined with an interactive Internet-based (II intervention for the management of menstrual pain and self-care of adolescents with primary dysmenorrhea. Design. This study adopts a pretest/posttest control research design with a convenience sample of 107 participants. Results. The outcomes were measured using the short-form McGill pain questionnaire (SF-MPQ, visual analogue scale (VAS, menstrual distress questionnaire (MDQ, and adolescent dysmenorrheic self-care scale (ADSCS. Significant differences were found in ADSCS scores between the groups, and in SF-MPQ, VAS, MDQ, and ADSCS scores for each group. Conclusion. Auricular acupressure alone and a combination of auricular acupressure and interactive Internet both reduced menstrual pain and distress for primary dysmenorrhea. Auricular acupressure combined with interactive Internet instruction is better than auricular acupuncture alone in improving self-care behaviors.

  17. Fibrilación auricular en el postoperatorio de cirugía cardíaca: Prevalencia y tiempo de internación Atrial fibrillation in postoperative cardiac surgery: Prevalence and hospitalized period

    Directory of Open Access Journals (Sweden)

    Alejandro E. Contreras

    2010-08-01

    Full Text Available La fibrilación auricular es el trastorno del ritmo más frecuente luego de la cirugía cardíaca. En estudios previos se ha asociado a prolongación de la internación, aumento en los costos e incremento en la mortalidad. El objetivo de este estudio fue conocer la prevalencia de fibrilación auricular en el postoperatorio de cirugía cardíaca y determinar el efecto en el tiempo de estadía hospitalaria. Se analizaron retrospectivamente las historias clínicas de pacientes sometidos a cirugía cardíaca consecutivamente (de revascularización miocárdica, valvulares o ambas entre enero 2006 y noviembre 2008. El punto final evaluado en el postoperatorio fue la presencia de fibrilación auricular. Se dividió a la muestra en dos grupos según tuvieran o no fibrilación auricular, y se compararon las variables clínicas y el tiempo de estadía hospitalaria. Ciento setenta y dos pacientes fueron operados en este período. Se excluyeron del análisis siete pacientes por falta de datos. La edad media fue 64.2 ± 9.5 años, con predominio del sexo masculino. La fibrilación auricular fue la complicación más frecuente (23.6%. El tiempo promedio de internación fue 6.7 ± 4.6 días. No hubo diferencias relevantes al comparar la estadía hospitalaria entre los grupos con o sin fibrilación auricular, 7.5 ± 4.1 días vs. 6.5 ± 4.7 días respectivamente, p = 0.21. La presencia de fibrilación auricular no prolongó la hospitalización. Probablemente una estrategia de prevención indiscriminada no sería costo-efectiva.Atrial fibrillation is the most common heart rhythm disorder after cardiac surgery. In previous studies it has been associated with prolonged hospitalization, increased costs and mortality. This study aimed to determine the prevalence of postoperative atrial fibrillation in cardiac surgery and its impact on the hospitalization period. Medical records of consecutive patients undergoing cardiac surgery (coronary artery bypass graft

  18. Refinamientos en la reconstrucción del tercio superior auricular con la técnica de Davis: Estudio anatómico y serie clínica Refinements on reconstruction of auricular upper pole defects with Davi's technique: Anatomical study and clinical series

    Directory of Open Access Journals (Sweden)

    S. Llanos

    2009-06-01

    Full Text Available Los defectos del tercio superior auricular son un desafío reconstructivo. Están descritas diferentes técnicas quirúrgicas para este fin con resultados a veces desfavorables Realizamos un estudio anatómico en cadáveres frescos que mostró la presencia constante de un pedículo neurovascular que penetra la raíz del hélix. Mostramos la localización y los diámetros de los vasos. Basándonos en este estudio anatómico, presentamos una serie de 10 casos consecutivos tratados por el autor principal. Analizamos la etiología, técnica quirúrgica, complicaciones y resultado a largo plazo. La técnica del autor introduce refinamientos a la técnica de Davis, el cual usa un colgajo condrocutáneo de concha auricular basado en la rama superior de la arteria temporal superficial y un colgajo cutáneo axial de base superior basado en la arteria retroauricular, para crear el nuevo hélix auricular superior. El aspecto posterior de este colgajo condrocutáneo se cubre con un injerto de piel total. En un segundo tiempo empleamos una zetaplastia de la base del hélix que nos dará una mejor forma. El estudio anatómico demostró la presencia de un pedículo neurovascular que penetra la raíz del hélix. La serie clínica está compuesta por 8 defectos postraumáticos, una quemadura eléctrica y un tumor de piel. Todos los colgajos condrocutáneos de concha auricular sobrevivieron comprobándose la seguridad del pedículo del hélix. Dos colgajos retroauriculares presentaron sufrimiento vascular transitorio distal, uno de ellos con recuperación completa y otro con necrosis distal mínima. Dos casos sufrieron pérdida parcial del injerto de piel total. Durante el desarrollo de la serie descubrimos algunos detalles de la técnica quirúrgica, que ahora discutimos en el artículo. Todos los pacientes recuperaron el contorno auricular, obteniendo los mejores resultados en aquellos en los que se aplicaron los refinamientos descritos. En conclusión, creemos

  19. Effect of Auricular Acupressure on Peri- and Early Postmenopausal Women with Anxiety: A Double-Blinded, Randomized, and Controlled Pilot Study

    OpenAIRE

    Ching-Ling Kao; Chao-Hsun Chen; Wei-Yun Lin; Yu-Ching Chiao; Ching-Liang Hsieh

    2012-01-01

    We tested effects of auricular acupressure on peri- and early postmenopausal women with anxiety (PPWA). Fifty PPWA were randomly assigned to the auricular acupressure group (AG) or the sham group (SG). After 3 meals and before sleep every day for 4 weeks, the AG received auricular acupressure on the bilateral ear shenmen and subcortex points for 3 min per point on alternating ears. The SG received sham auricular acupressure. The Alprazolam was reduced from 0.5 mg/day at baseline to 0.3 mg/day...

  20. In Vitro Antioxidant Activities of Sulfated Derivatives of Polysaccharides Extracted from Auricularia auricular

    Science.gov (United States)

    Zhang, Hua; Wang, Zhen-Yu; Yang, Lin; Yang, Xin; Wang, Xue; Zhang, Zhi

    2011-01-01

    In this research, two types of sulfated polysaccharide derivatives were successfully synthesized. Their antioxidant activities were investigated by employing various established in vitro systems. In addition, the degree of sulfation was evaluated using ion-chromatography and IR spectra. The results verify that, when employing scavenging superoxide radical tests, both the sulfation of acid Auricularia auricular polysaccharides (SAAAP) and the sulfation of neutral Auricularia auricular polysaccharides (SNAAP) derivatives possessed considerable antioxidant activity and had a more powerful antioxidant competence than that of the native non-sulfated polysaccharides (AAAP and NAAP). On the other hand, AAAP and NAAP exhibited stronger activity on scavenging both the hydroxyl radical and lipid peroxidation. Available data obtained with in vitro measurements indicates that the sulfated groups of AAAP and NAAP played an important role on antioxidant activity. In sum, the research demonstrates that the antioxidant activity of sulfated polysaccharide derivatives in vitro has a potential significance for seeking new natural antioxidant protective agents. PMID:21686185

  1. CLINICAL OBSERVATION ON TREATMENT OF 61 CASES OF INSOMNIA WITH AURICULAR PLASTER THERAPY

    Institute of Scientific and Technical Information of China (English)

    张家彤; 王月

    2003-01-01

    Objective: To observe the therapeutic effect of auricular plaster (otopoint-pressure) therapy in thetreatment of insomnia. Methods: In this paper, 61 cases of insomnia patients including 16 males and 45 females weretreated with Ershenmen (MA-TF 1), Zhen (MA-AT), Yuanzhong (MA-AT), Nao Dian and E (MA-AT), combined withother otopoints according to symptoms. The otopoint was stuck with a piece of plaster adhered with vaccaria seeds andpressured by the patient him- or her-self. The treatment was given twice a week, with 7 times being a therapeuticcourse. Results: After 1 - 2 courses of treatment, 19 (31.15%) cases were cured, 34 (55.74 % ) had improvementand 8 (13.11%) had no changes, with the total effective rate being 86.9%. Conclusion: Auricular plaster therapyworks well in the treatment of insomnia patient.

  2. A Simplified Technique for Orientation of a Bone Anchored Auricular Prostheses: a Clinical Report

    Directory of Open Access Journals (Sweden)

    Hussein G. El Charkawi

    2012-08-01

    Full Text Available Background: A simple technique was presented in this clinical report for orientation of a bone anchored auricular prosthesis.Methods: The proposed technique includes drawing the intact ear on a transparent celluloid paper or radiographic film and flipping it to the opposite side and relating it to the fixed anatomical features on the face of patient.Results: The drawing, by this way provides a simple and easy way to duplicate and transfer the exact size and position of the intact ear to the defect side.Conclusions: This technique provides a simple, safe, inexpensive and time saving yet, an accurate and effective surgical template that orients the craniofacial implants to the confines of the definitive auricular prosthesis. It is indicated for restoration of single missing external ear either in aplasia, injuries and total resection.

  3. Effect of self-administered auricular acupressure on smoking cessation --a pilot study

    OpenAIRE

    Leung Lawrence; Neufeld Troy; Marin Scott

    2012-01-01

    Abstract Background Tobacco smoking is still a worldwide health risk. Current pharmacotherapies have at best, a success rate of no more than 50%. Auricular (ear) acupressure has been purported to be beneficial in achieving smoking cessation in some studies, while in others has been deemed insignificant. We hereby describe the protocol for a three-arm randomised controlled trial to examine the possible benefits of self-administered acupressure for smoking cessation. Methods Sixty consenting pa...

  4. Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

    OpenAIRE

    Xin-Yan Gao; Lu Wang; Ingrid Gaischek; Yvonne Michenthaler; Bing Zhu; Gerhard Litscher

    2011-01-01

    Auricular acupuncture has been described in ancient China as well as Egypt, Greece, and Rome. At the end of the 1950s, ear acupuncture was further developed by the French physician Dr. Paul Nogier. The goal of this study was to develop a new system for ear acupressure (vibration stimulation) and to perform pilot investigations on the possible acute effects of vibration and manual ear acupressure on heart rate (HR), heart rate variability (HRV), pulse wave velocity (PWV), and the augmentation ...

  5. Acupressure, reflexology, and auricular acupressure for insomnia: A systematic review of randomized controlled trials

    OpenAIRE

    Chung, KF; Zhang, ZJ; Poon, MMK; Ho, FYY; Zhang, SP; Ziea, ETC; Wong, VT; Yeung, WF

    2012-01-01

    Previous randomized controlled trials (RCTs) have shown that acupuncture may be efficacious for insomnia. Instead of needling, acupressure, reflexology, and auricular acupressure are procedures involving physical pressure on acupoints or reflex areas. These variants of acupuncture are gaining popularity, perhaps due to their non-invasive nature. A systematic review has therefore been conducted to examine their efficacy and safety for insomnia. Two independent researchers searched five English...

  6. Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial

    OpenAIRE

    Cui-na Yan; Wei-guo Yao; Yi-jie Bao; Xiao-jing Shi; Hui Yu; Pei-hao Yin; Gui-zhen Liu

    2015-01-01

    Background. Uremic pruritus (UP) is a common symptom in patients undergoing maintenance hemodialysis for end-stage renal disease (ESRD). Objective. To determine the clinical efficacy of auricular acupressure therapy on pruritus in hemodialysis patients and to explore possible underlying mechanisms. Methods. Patients receiving maintenance hemodialysis at a referral medical center were recruited and assigned to intervention (n = 32) and control (n = 30) groups. The intervention group underwent ...

  7. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain

    OpenAIRE

    Wei-Chun Lin; Chao Hsing Yeh; Lung-Chang Chien; Morone, Natalia E.; Glick, Ronald M.; Albers, Kathryn M.

    2015-01-01

    Background. Auricular point acupressure (APA) is a promising treatment for pain management. Few studies have investigated the physiological mechanisms of APA analgesics. Method. In this pilot randomized clinical trial (RCT), a 4-week APA treatment was used to manage chronic low back pain (CLBP). Sixty-one participants were randomized into a real APA group (n = 32) or a sham APA group (n = 29). Blood samples, pain intensity, and physical function were collected at baseline and after 4 weeks of...

  8. Upper and middle third auricular reconstruction with a peninsular conchal flap

    OpenAIRE

    Fikret Eren; Bilge Kagan Aysal; Cenk Melikoglu; Sinan Oksuz

    2016-01-01

    Background: Traumatic or iatrogenic full thickness auricular defects can be reconstructed in many ways. The defects exceeding 2 cm require challenging reconstruction techniques. The reconstruction options for those should include an- terior and posterior skin envelope repair with cartilaginous content. Providing color and texture match, while maintaining anatomic landmarks, should be considered. The outcomes of patients in which we used a peninsular conchal axial pattern flap (PCF) to reconst...

  9. Role of Insulin-Transferrin-Selenium in Auricular Chondrocyte Proliferation and Engineered Cartilage Formation in Vitro

    Directory of Open Access Journals (Sweden)

    Xia Liu

    2014-01-01

    Full Text Available The goal of this study is to determine the effects of Insulin-Transferrin-Selenium (ITS on proliferation of auricular chondrocytes and formation of engineered cartilage in vitro. Pig auricular monolayer chondrocytes and chondrocyte pellets were cultured in media containing 1% ITS at different concentrations of fetal bovine serum (FBS, 10%, 6%, 2%, 0%, or 10% FBS alone as a control for four weeks. Parameters including cell proliferation in monolayer, wet weight, collagen type I/II/X (Col I, II, X and glycosaminoglycan (GAG expression, GAG content of pellets and gene expression associated with cartilage formation/dedifferentiation (lost cartilage phenotype/hypertrophy within the chondrocyte pellets were assessed. The results showed that chondrocytes proliferation rates increased when FBS concentrations increased (2%, 6%, 10% FBS in ITS supplemented groups. In addition, 1% ITS plus 10% FBS significantly promoted cell proliferation than 10% FBS alone. No chondrocytes grew in ITS alone medium. 1% ITS plus 10% FBS enhanced cartilage formation in terms of size, wet weight, cartilage specific matrices, and homogeneity, compared to 10% FBS alone group. Furthermore, ITS prevented engineered cartilage from dedifferentiation (i.e., higher index of Col II/Col I mRNA expression and expression of aggrecan and hypertrophy (i.e., lower mRNA expression of Col X and MMP13. In conclusion, our results indicated that ITS efficiently enhanced auricular chondrocytes proliferation, retained chondrogenic phenotypes, and promoted engineered cartilage formation when combined with FBS, which is potentially used as key supplementation in auricular chondrocytes and engineered cartilage culture.

  10. Observations on the Efficacy of Auricular-plaster Therapy plus Medicine in Treating Heroin Addiction

    Institute of Scientific and Technical Information of China (English)

    王泽涛; 袁宜勤; 王军; 罗杰坤

    2006-01-01

    Objective:To investigate the curative effect of auricular-plaster therapy on heroin addiction. Methods: Sixty cases of heroin addiction were treated by auricular-plaster therapy in cooperation with methadone and another 60 cases with methadone as a control. The treatment lasted 10 days. Results and conclusion: The results showed that the curative effect of auricular-plaster therapy plus methadone on heroin addiction was significantly better than that of methadone in the control group(P<0.01). The rate of drug relapse was also significantly lower in the former(P<0.01). It is considered that auricular-plaster therapy in cooperation with methadone is now an ideal therapeutic method for drug withdrawal.%目的:观察耳穴贴压治疗海洛因依赖的疗效.方法:耳穴贴压配合西药美沙酮治疗海洛因依赖60例,并与美沙酮治疗60例作对照,临床戒毒观察10 d.结果与结论:结果表明,耳穴贴压配合西药美沙酮戒毒疗效明显优于对照组美沙酮的戒毒疗效(P《0.01),其复吸率也低(P《0.01).认为耳穴贴压配合西药美沙酮戒毒是目前比较理想的戒毒治疗方法.

  11. Isolation, identification, and comparison of cartilage stem progenitor/cells from auricular cartilage and perichondrium

    OpenAIRE

    Xue, Ke; Zhang, Xiaodie; Qi, Lin; Zhou, Jia; Liu, Kai

    2016-01-01

    Auricular cartilage loss or defect remains a challenge to plastic surgeons, and cartilage regenerative medicine provides a novel method to solve the problem. However, ideal seeding cells seem to be the key point in the development of cartilage regeneration. Although bone marrow-mesenchymal stem cells were considered as the ideal seeding cells in cartilage regeneration, regenerative cartilage differentiated from bone marrow-mesenchymal stem cells still faces some problems. It is reported that ...

  12. Characterization of pediatric microtia cartilage: a reservoir of chondrocytes for auricular reconstruction using tissue engineering strategies.

    Science.gov (United States)

    Melgarejo-Ramírez, Y; Sánchez-Sánchez, R; García-López, J; Brena-Molina, A M; Gutiérrez-Gómez, C; Ibarra, C; Velasquillo, C

    2016-09-01

    The external ear is composed of elastic cartilage. Microtia is a congenital malformation of the external ear that involves a small reduction in size or a complete absence. The aim of tissue engineering is to regenerate tissues and organs clinically implantable based on the utilization of cells and biomaterials. Remnants from microtia represent a source of cells for auricular reconstruction using tissue engineering. To examine the macromolecular architecture of microtia cartilage and behavior of chondrocytes, in order to enrich the knowledge of this type of cartilage as a cell reservoir. Auricular cartilage remnants were obtained from pediatric patients with microtia undergoing reconstructive procedures. Extracellular matrix composition was characterized using immunofluorescence and histological staining methods. Chondrocytes were isolated and expanded in vitro using a mechanical-enzymatic protocol. Chondrocyte phenotype was analyzed using qualitative PCR. Microtia cartilage preserves structural organization similar to healthy elastic cartilage. Extracellular matrix is composed of typical cartilage proteins such as type II collagen, elastin and proteoglycans. Chondrocytes displayed morphological features similar to chondrocytes derived from healthy cartilage, expressing SOX9, COL2 and ELN, thus preserving chondral phenotype. Cell viability was 94.6 % during in vitro expansion. Elastic cartilage from microtia has similar characteristics, both architectural and biochemical to healthy cartilage. We confirmed the suitability of microtia remnant as a reservoir of chondrocytes with potential to be expanded in vitro, maintaining phenotypical features and viability. Microtia remnants are an accessible source of autologous cells for auricular reconstruction using tissue engineering strategies. PMID:27566509

  13. Auricular Point Acupressure for Chronic Low Back Pain: A Feasibility Study for 1-Week Treatment

    Directory of Open Access Journals (Sweden)

    Chao-Hsing Yeh

    2012-01-01

    Full Text Available Objectives. The objective of this one-group, repeated-measures design was to explore the acceptance of auricular point acupressure (APA to reduce chronic low back pain (CLBP and estimate minimum clinically important differences (MCIDs for pain intensity change. Methods. Subjects received 7-day APA treatment. After appropriate acupoints were identified, vaccaria seeds were carefully taped onto each selected auricular point for 7-day. The Brief Pain Inventory Short Form (BPI was used to collect outcome data. Results. A total of 74 subjects participated in the study. Ten subjects dropped out and the retention rate was 87%. Subjects reported a 46% reduction in BPI worst pain, and over 50% reduction in BPI average pain, overall pain severity and pain interference by the end of study, and 62.5% subjects also reported less pain medication use. The MCIDs for the subscale of BPI ranged from .70 to 1.86 points. The percentage improvement of MCIDs from baseline was between 14.5–24.9%. Discussion. APA appears to be highly acceptable to patients with CLBP. A sham group is needed in order to differentiate the true effects of APA from the possible psychological effects of more frequent visits by the auricular therapist and patients’ expectation of the APA treatment.

  14. A Randomized Controlled Trial of Auricular Transcutaneous Electrical Nerve Stimulation for Managing Posthysterectomy Pain

    Directory of Open Access Journals (Sweden)

    Hin Cheung Tsang

    2011-01-01

    Result. As compared to the baseline, only the true TENS group reported a significant reduction in VAS-rest (P=.001, VAS-huff (P=.004, and VAS-cough (P=.001, while no significant reduction in any of the VAS scores was seen in the sham TENS group (all P>.05. In contrast, a small rising trend was observed in the VAS-rest and VAS-huff scores of the control group, while the VAS-cough score remained largely unchanged during the period of the study. A between-group comparison revealed that all three VAS scores of the true TENS group were significantly lower than those of the control group at 15 and 30 minutes after the intervention (all P<.02. No significant between-group difference was observed in PEFR at any point in time. Conclusion. A single session of auricular TENS applied at specific therapeutic points significantly reduced resting (VAS-rest and movement-evoked pain (VAS-huff, VAS-cough, and the effects lasted for at least 30 minutes after the stimulation. The analgesic effects of auricular TENS appeared to be point specific and could not be attributed to the placebo effect alone. However, auricular TENS did not produce any significant improvement in the performance of PEFR.

  15. Association of auricular pressing and heart rate variability in pre-exam anxiety students

    Institute of Scientific and Technical Information of China (English)

    Wocao Wu; Junqi Chen; chuan Zhen; Huanlin Huang; Pei Zhang; Jiao Wang; Yingyi Ou; Yong Huang

    2013-01-01

    A total of 30 students scoring between 12 and 20 on the Test Anxiety Scale who had been exhibiting an anxious state > 24 hours, and 30 normal control students were recruited. Indices of heart rate variability were recorded using an Actiheart electrocardiogram recorder at 10 minutes before auricular pressing, in the first half of stimulation and in the second half of stimulation. The results revealed that the standard deviation of all normal to normal intervals and the root mean square of standard deviation of normal to normal intervals were significantly increased after stimulation. The heart rate variability triangular index, very-low-frequency power, low-frequency power, and the ratio of low-frequency to high-frequency power were increased to different degrees after stimulation. Compared with normal controls, the root mean square of standard deviation of normal to normal intervals was significantly increased in anxious students following auricular pressing. These results indicated that auricular pressing can elevate heart rate variability, especially the root mean square of standard deviation of normal to normal intervals in students with pre-exam anxiety.

  16. Phylogenetic analysis of New World screwworm fly, Cochliomyia hominivorax, suggests genetic isolation of some Caribbean island populations following colonization from South America.

    Science.gov (United States)

    McDonagh, L; García, R; Stevens, J R

    2009-06-01

    Larval infestations of the New World screwworm (NWS) fly, Cochliomyia hominivorax, cause considerable economic losses through the direct mortality and reduced production of livestock. Since the 1950s, NWS populations in North and Central America have been the target of virtually continuous eradication attempts by sterile insect technique (SIT). Nevertheless, in some areas, such as Jamaica, SIT-based control programmes have failed. Reasons for the failure of SIT-based programmes in some locations are unknown, but it is hypothesized that failure may be related to the mating incompatibility between sterile and wild flies or to the existence of sexually incompatible cryptic species. Accordingly, the current research investigates intraspecific phylogenetic relationships and associated biogeographic patterns between NWS populations from the Caribbean and South America, which represent those populations involved in, or earmarked for, forthcoming SIT programmes. Uniquely, this study also includes analyses of two North American samples, collected in Texas in 1933 and 1953 prior to initiation of the SIT-based eradication programme. The study utilizes three nucleotide datasets: elongation factor-1alpha (nuclear); cytochrome oxidase subunit 1 (mitochondrial), and 12S rRNA (mitochondrial). Phylogenetic analysis of these data, representing populations from across the Caribbean, South America and Texas, indicates sub-structuring of fly populations on several of the larger Caribbean islands, suggesting a period of isolation and/or founder effects following colonization from South America; significantly, our findings do not support a North American origin for Cuban flies. The importance of these findings in the light of proposed SIT programmes in the region is discussed. PMID:19335826

  17. Vasoconstrictive Responses by the Carotid and Auricular Arteries in goats to Ergot Alkaloid Exposure

    Science.gov (United States)

    Aiken, Glen; Flythe, Michael

    2014-11-01

    A fungal endophyte (Neotyphodium coenophialum) infects most plants of ‘Kentucky 31’ tall fescue (Lolium arundinaceum) and produces ergot alkaloids that cause persistent constriction of the vascular system in grazing livestock. Consequently, animals undergoing this toxicosis cannot regulate core body temperature and are vulnerable to heat and cold stresses. An experiment was conducted to determine if the caudal and auricular arteries in goats (Capra aegagrus hircus) vasoconstrict in response to ergot alkaloids. Seven, rumen fistulated goats were fed ad libitum orchardgrass (Dactylis glomeratia) hay and ruminally infused with endophtye-free seed (E-) for a 7-day adjustment period. Two periods followed with E- and endophyte-infected (E+) seed being randomly assigned to the 2 goat groups in period 1 and then switching treatments between groups in period 2. Infused E+ and E- seed were in equal proportions to the hay such that concentrations of ergovaline and ergovalanine were 0.80 µg per g dry matter for the E+ treatment. Cross-sections of both arteries were imaged using Doppler ultrasonography on days 0, 2, 4, 6, 8, and 12 in period 1 and on days 0, 1, 2, 3, 6, 7, and 9 in period 2. Differences from average baseline areas were used to determine presence or absence of alkaloid-induced vasoconstriction. Carotid arteries initiated constriction on imaging day 2 in both periods, and auricular arteries initiated constriction on imaging day 2 in period 1 and on day 6 in period 2. Luminal areas of the carotid arteries in E+ goats were 46% less than baseline areas in both periods after vasoconstriction occurred, whereas auricular arteries in E+ goats were 52% less than baseline areas in period 1 and 38% in period 2. Both arteries in E+ goats in period 1 relaxed relative to baseline areas by imaging day 2 after they were switched to the E- treatment. Results indicated that goats can vasoconstrict when exposed to ergot alkaloids that could disrupt their thermoregulation.

  18. Fibrilhação auricular e doenças não cardiovasculares

    OpenAIRE

    Ferreira, Cátia Andreia dos Santos

    2015-01-01

    A fibrilhação auricular (FA) é a arritmia cardíaca mais comum e está associada a um prognóstico adverso, aumentando o risco de acidente vascular cerebral e a mortalidade. Apesar de tradicionalmente se associar a FA a patologias cardiovasculares, também se verifica uma incidência aumentada de FA em determinadas patologias não cardiovasculares bastante prevalentes na população geral, nomeadamente no cancro, na sépsis, na doença pulmonar obstrutiva crónica, na síndrome da apneia obstrutiva do so...

  19. STUDY ON THE INTERRELATION BETWEEN AURICULAR GOOD CONDUCTION POINT STIMULATION AND THE THERAPEUTIC EFFECT

    Institute of Scientific and Technical Information of China (English)

    胡智慧; 陈巩荪

    2001-01-01

    Although, the essence of otopoints remains unknown at the moment, many medical workers have termed them temporarily as "auricular specific stimulating points". They give an explanation that when the internal organs or the body trunk is out of order, tender points, changes of the cutaneous electrical resistance, appearance, colour, etc. may occur at some sites of the auri-cle. The medical workers can use these reactions as a reference for making a diagnosis and stimulate these sites to prevent and treat diseases. These reaction points are also the otopoint. Therefore, the otopoint is also called as tenderpoint, or good conduction point, reaction point, stimulating point or treatment point.

  20. Effectiveness of medication / auricular therapy / phyto-therapy combination in the treatment of hypertensive patients

    OpenAIRE

    José Ramón Martínez Pérez; Lourdes Leonor Bermúdez Cordoví; Zoraida de los Ángeles Cruz Paz; Yanmila Falcón Diéguez

    2015-01-01

    Background: hypertension is one of the main cardiovascular risk factors, so its control improves the life expectancy of patients.Objective: to assess the effects of a treatment combining medication with auricular therapy and phyto-therapy in hypertensive patients assisted at the health area of ”Romárico Oro” Polyclinic, in Puerto Padre, Las Tunas province.Methods: an intervention study was carried out in 68 hypertensive patients of the health area of “Romárico Oro” Polyclinic in Puerto Padre ...

  1. Treatment of Stye by Auricular Point Blood-letting Therapy: A Report of 85 Cases

    Institute of Scientific and Technical Information of China (English)

    WANG Zhan-hui

    2005-01-01

    Eighty-five cases of stye were treated by pricking and extruding some blood in auricular points Eye 1 and Eye 2. After 5 treatments, 63 cases were cured, 17 cases obtained improvement, 5 cases obtained no effects, and the total effective rate is 94.1%.%点刺耳穴目1和目2,并挤压出血,治疗85例麦粒肿患者,经过5次治疗,治愈63例,好转17例,无效5例,总有效率94.1%.

  2. Aturdimiento atrial y cardioversión en la fibrilación auricular

    OpenAIRE

    Rodríguez Blanco, Víctor Manuel

    2016-01-01

    NTRODUCCIÓN Y JUSTIFICACIÓN La fibrilación auricular es la arritmia mantenida más frecuente en la práctica clínica. Una de sus principales complicaciones es la aparición de cuadros embólicos, en ocasiones asociados a intentos de revertir la arritmia. La cardioversión produce una disfunción mecánica transitoria que puede dar lugar a que dichos eventos aparezcan después de varias semanas tras el procedimiento. Ante la diversidad de opiniones en la literatura sobre si dicha disfunción es d...

  3. Clinical Observation on the Treatment of Post-cesarean Hypogalactia by Auricular Points Sticking-Pressing

    Institute of Scientific and Technical Information of China (English)

    周海燕; 李力; 李丹; 李霞; 孟红娟; 高雪梅; 姜慧君; 曹丽蓉; 朱一麟

    2009-01-01

    Objective:To explore the effect of auricular points sticking-pressing(APSP) in treating postcesarean hypogalactia(PCH).Methods:A randomized,controlled,single-blinded clinical trial on 116 patients with PCH was carried out.They were equally assigned to the treatment group and the control group.The treatment group received APSP,with the pellets pressed for 4 times daily,while the control group was only asked to do lactation to meet infant demand.The therapeutic efficacy and the changes in scores of traditi...

  4. Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

    Directory of Open Access Journals (Sweden)

    Xin-Yan Gao

    2012-01-01

    Full Text Available Auricular acupuncture has been described in ancient China as well as Egypt, Greece, and Rome. At the end of the 1950s, ear acupuncture was further developed by the French physician Dr. Paul Nogier. The goal of this study was to develop a new system for ear acupressure (vibration stimulation and to perform pilot investigations on the possible acute effects of vibration and manual ear acupressure on heart rate (HR, heart rate variability (HRV, pulse wave velocity (PWV, and the augmentation index (AIx using new noninvasive recording methods. Investigations were performed in 14 healthy volunteers (mean age ± SD: 26.3±4.3 years; 9 females, 5 males before, during, and after acupressure vibration and manual acupressure stimulation at the “heart” auricular acupuncture point. The results showed a significant decrease in HR (≤0.001 and a significant increase in HRV total (=0.008 after manual ear acupressure. The PWV decreased markedly (yet insignificantly whereas the AIx increased immediately after both methods of stimulation. The increase in the low-frequency band of HRV was mainly based on the intensification of the related mechanism of blood pressure regulation (10-s-rhythm. Further studies in Beijing using animal models and investigations in Graz using human subjects are already in progress.

  5. Auricular Acupuncture for Pain Relief after Ambulatory Knee Arthroscopy—A Pilot Study

    Directory of Open Access Journals (Sweden)

    Taras I. Usichenko

    2005-01-01

    Full Text Available Auricular acupuncture (AA is effective in treating various pain conditions, but there have been no analyses of AA for the treatment of pain after ambulatory knee surgery. We assessed the range of analgesic requirements under AA after ambulatory knee arthroscopy. Twenty patients randomly received a true AA procedure (Lung, Shenmen and Knee points or sham procedure (three non-acupuncture points on the auricular helix before ambulatory knee arthroscopy. Permanent press AA needles were retained in situ for one day after surgery. Post-operative pain was treated with non-steroidal anti-inflammatory ibuprofen, and weak oral opioid tramadol was used for rescue analgesic medication. The quantity of post-operative analgesics and pain intensity were used to assess the effect of AA. The incidence of analgesia-related side effects, time to discharge from the anesthesia recovery room, heart rate and blood pressure were also recorded. Ibuprofen consumption after surgery in the AA group was lower than in the control group: median 500 versus 800 mg, P = 0.043. Pain intensity on a 100 mm visual analogue scale for pain measurement and other parameters were similar in both groups. Thus AA might be useful in reducing the post-operative analgesic requirement after ambulatory knee arthroscopy.

  6. The Effects and Measures of Auricular Acupressure and Interactive Multimedia for Smoking Cessation in College Students

    Directory of Open Access Journals (Sweden)

    Mei-Ling Yeh

    2014-01-01

    Full Text Available The earlier one starts to smoke, the more likely it is that one’s tobacco use will increase. Either auricular acupressure or multimedia education could improve physiological health status and reduce smoking for young smokers. This study aimed to evaluate the effects of a 10-week auricular acupressure (AA and interactive multimedia (IM on smoking cessation in college smokers. A pre- and posttest control research design with two experiments (AA and IM and one control was used. Thirty-two participants were in each of three groups. A significant difference from pretest to posttest among three groups was exhibited on carbon monoxide (CO, cotinine, and nicotine dependence. Scheffe’s post hoc test found significances on CO in the AA between the IM and the control and cotinine and nicotine dependence between the AA and the control. After controlling the covariates, the main effect of the group was no difference in all outcomes. The interventions, especially AA, may contribute to a decrease of CO, cotinine, and nicotine dependence along with the time change. An analysis without controlling influences may overestimate interventional effects.

  7. Agreement between auricular and rectal measurements of body temperature in healthy cats.

    Science.gov (United States)

    Sousa, Marlos G; Carareto, Roberta; Pereira-Junior, Valdo A; Aquino, Monally C C

    2013-04-01

    Measurement of body temperature is a routine part of the clinical assessment of a patient. However, this procedure may be time-consuming and stressful to most animals because the standard site of temperature acquisition remains the rectal mucosa. Although an increasing number of clinicians have been using auricular temperature to estimate core body temperature, evidence is still lacking regarding agreement between these two methods in cats. In this investigation, we evaluated the agreement between temperatures measured in the rectum and ear in 29 healthy cats over a 2-week period. Temperatures were measured in the rectum (using digital and mercury-in-glass thermometers) and ear once a day for 14 consecutive days, producing 406 temperature readings for each thermometer. Mean temperature and confidence intervals were similar between methods, and Bland-Altman plots showed small biases and narrow limits of agreement acceptable for clinical purposes. The interobserver variability was also checked, which indicated a strong correlation between two near-simultaneous temperature readings. Results are consistent with auricular thermometry being a reliable alternative to rectal thermometry for assessing core body temperature in healthy cats.

  8. CLINICAL STUDY ON CLIMACTERIC SYNDROME TREATED WITH AURICULAR PLUS BODY ACUPUNCTURE

    Institute of Scientific and Technical Information of China (English)

    徐天舒

    2003-01-01

    Aim: To search for the best therapeutic method for climacteric syndrome. Methods: A total of 190 cases of climacteric syndrome participants were randomly divided into auricular plus body acupuncture group (treatment group, n = 96) and simple body acupuncture group (control group, n = 94). Serum sexual hormone (FSH, LH and E2) and blood lipid (TC, LDL-C, HDL-C and TG) levels were detected before and after treatment. Results: After 30sessions of treatment, the total effective rates of treatment and control groups were 82.29% and 76.02% respectively, with the former being significantly higher than the later ( P < 0.01 ). In comparison with pre-treatment of each group, serum follicle-stimulating hormone (FSH) and luterotropic hormone (LH) levels lowered significantly; serum estradiol (E2) increased remarkably ( P < 0.05 - 0.01 ); serum high-density l ipoprotein-cholesterol (HDL-C) of two groups raised significantly ( P< 0.05- 0.01 ), and Iow-density lipoprotein (LDL)-C of treatment group decreased evidently (P< 0.05). In addition, the improvement of complaints of hot flushes, sweating, paresthesia, insomnia and emotional irritability in treatment group is significantly better than that of control group. Conclusion: Auricular acupuncture combined with body acupuncture has a better therapeutic effect than that of simple body acupuncture in the treatment of climacteric syndrome.

  9. Auricular Acupressure to Improve Menstrual Pain and Menstrual Distress and Heart Rate Variability for Primary Dysmenorrhea in Youth with Stress

    OpenAIRE

    Yu-Jen Wang; Chin-Che Hsu; Mei-Ling Yeh; Jaung-Geng Lin

    2013-01-01

    Background. Dysmenorrhea and accompanying symptoms can have a negative impact on academic achievement, physical activity and functioning, and quality of life. Unfortunately, stress increases the sensitivity and severity of pain, activating sympathetic responses while inhibiting parasympathetic responses. Objective. This study used objective, physiological measurements to evaluate the effects of auricular acupressure on menstrual pain and menstrual distress in young college students with prima...

  10. The Stimulation Effect of Auricular Magnetic Press Pellets on Older Female Adults with Sleep Disturbance Undergoing Polysomnographic Evaluation

    Directory of Open Access Journals (Sweden)

    Chyi Lo

    2013-01-01

    Full Text Available Study Objectives. To examine the stimulation effect of auricular magnetic press pellet therapy on older female adults with sleep disturbance as determined by polysomnography (PSG. Design. Randomized, single-blind, experimental-controlled, parallel-group. Setting. Community. Participants. Twenty-seven older female adults with sleep disturbance according to the Pittsburgh Sleep Quality Index (PSQI >5 for at least 3 months were recruited. Participants were screened by both the Hospital Anxiety and Depression Scale (HADS and the Mini-Mental State Examination (MMSE, as well as polysomnography prior to randomization. Interventions. All eligible participants were randomly allocated into the experimental or control group. Both groups were taped with magnetic press pellet on auricular points for 3 weeks. The experimental group was treated by applying pressure on the magnetic press pellets 3 times per day while no stimulation was applied on the control group. Measurements and Results. Both groups were measured by PSG and PSQI at the beginning of the study and 3 weeks after the study. Both groups showed improvements on PSQI scores compared to the baseline. One-way analysis of covariance adjusted for baseline scores showed that significant improvements of PSG-derived sleep parameters, such as sleep efficiency, were found in the experimental group. However, no significant differences between groups were observed in the proportion of sleep stages with the exception of Stage 2. Conclusions. Auricular therapy using magnetic pellets and stimulation by pressing was more effective in improving the sleep quality compared to auricular therapy without any stimulation.

  11. Effect of Auricular Acupuncture with Low Power Laser on Four Chronic Allergic Dermatoses and Serum IgE Level

    Institute of Scientific and Technical Information of China (English)

    You-hong Hou; Fang Xu; Shao-xi Wu

    2005-01-01

    @@ The objective of the study was to investigate the effectiveness of low power laser irradiating auricular points on four chronic allergic dermatoses including eczema, urticaria, facial cosmetic dermatitis, and atopic dermatitis, and on the changes of serum IgE level.

  12. Fifty Cases of Child Restless Syndrome Treated with the Integrated Method of Chinese Herbal Drugs and Auricular-Plaster Therapy

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Fifty cases of child restless syndrome were treated with oral administration of Chinese traditional herbal drugs plus auricular-plaster therapy from December 1998 to November 2001, and another 47 cases were treated with oral administration of methylphenidate as controls. The result is reported as follows.

  13. Gangrena de pavilhão auricular como primeira manifestação de síndrome do anticorpo antifosfolípide Gangrene of the auricle as the first sign of antiphospholipid antibody syndrome

    OpenAIRE

    Erika Bettini de Sá; Adson da Silva Passos; Mariana Cecconi; Maria Lourdes Peris Barbo; José Eduardo Martinez; Gilberto Santos Novaes

    2011-01-01

    A síndrome do anticorpo antifosfolípide (SAF), mais comum em mulheres, manifesta-se clinicamente como trombose e/ou abortamentos de repetição. Anemia hemolítica autoimune e manifestações neurológicas, cardíacas e cutâneas são comuns. Relata-se o caso de um paciente do gênero masculino cuja manifestação inicial da doença foi gangrena em pavilhão auricular, e o diagnóstico de SAF se deu por meio de biópsia de pele do membro inferior, que mostrava vasculopatia trombótica, sem evidência de vascul...

  14. High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities.

    Directory of Open Access Journals (Sweden)

    Alyssa J Reiffel

    Full Text Available INTRODUCTION: Autologous techniques for the reconstruction of pediatric microtia often result in suboptimal aesthetic outcomes and morbidity at the costal cartilage donor site. We therefore sought to combine digital photogrammetry with CAD/CAM techniques to develop collagen type I hydrogel scaffolds and their respective molds that would precisely mimic the normal anatomy of the patient-specific external ear as well as recapitulate the complex biomechanical properties of native auricular elastic cartilage while avoiding the morbidity of traditional autologous reconstructions. METHODS: Three-dimensional structures of normal pediatric ears were digitized and converted to virtual solids for mold design. Image-based synthetic reconstructions of these ears were fabricated from collagen type I hydrogels. Half were seeded with bovine auricular chondrocytes. Cellular and acellular constructs were implanted subcutaneously in the dorsa of nude rats and harvested after 1 and 3 months. RESULTS: Gross inspection revealed that acellular implants had significantly decreased in size by 1 month. Cellular constructs retained their contour/projection from the animals' dorsa, even after 3 months. Post-harvest weight of cellular constructs was significantly greater than that of acellular constructs after 1 and 3 months. Safranin O-staining revealed that cellular constructs demonstrated evidence of a self-assembled perichondrial layer and copious neocartilage deposition. Verhoeff staining of 1 month cellular constructs revealed de novo elastic cartilage deposition, which was even more extensive and robust after 3 months. The equilibrium modulus and hydraulic permeability of cellular constructs were not significantly different from native bovine auricular cartilage after 3 months. CONCLUSIONS: We have developed high-fidelity, biocompatible, patient-specific tissue-engineered constructs for auricular reconstruction which largely mimic the native auricle both

  15. Effect of Auricular Acupress Therapy on Insomnia of Cancer Patients : Randomized, Single Blinded, Placebo Controlled Trial

    Directory of Open Access Journals (Sweden)

    In-Sook Jung

    2010-06-01

    Full Text Available Background: Auricular acupressure is one of the traditional health care treatments in oriental medicine. Approximately, 30~40% of the cancer patients have said to be suffering from insomnia and half of them having chronic and severe insomnia at the same time. Insomnia caused cancer patients feel more pain, fatigue, depression and anxiety and it sometimes let the power to have the best of cancer pull down. Objective: To investigate how effective the auricular acupressure treatment to cancer patients suffering from insomnia. Methods: We recruited participants from East-West Cancer Center of Daejeon University. Finally, of the people whose age range from 20 to 75, 12 patients who got less than 40 points from the score of Oh's sleeping score (OSS were recruited. Single-blind, randomized pilot study was performed. The treatment group received auricular acupressure treatment (AAT on active points and the control group had received sham acupressure treatment (SAT for five times. Sleep parameters were checked by using OSS and numeric rating scale (NRS. We checked the scale everytime, both before and after treatment. We analyzed the data statistically by using independent T-test, paired T-test and analysis of variance (ANOVA test. (p<0.05 Results: Twelve cancer patients participated in this pilot study and there was no significant difference between control and treatment group. Only 7 of them had completed the whole treatment process, 4 patients of AAT group and 3 participants of SAT. The OSS of AAT group had increased from 34.0± 4.3 to 39.5±3.1 and that of SAT group had increased from 38.3±3.5 to 40.0±0.0. There was no significant difference between them. The NRS of AAT group had increased from 6.3±2.9 to 4.8±2.1 and that of SAT group had increased from 7.0±1.0 to 5.0±2.6. No significant difference was observed between them. Conclusion: Although both groups did not show significant differences, most of the experimental participants showed

  16. Changes in Sleep With Auricular Point Acupressure for Chronic Low Back Pain.

    Science.gov (United States)

    Yeh, Chao Hsing; Suen, Lorna Kwai-Ping; Shen, Juan; Chien, Lung-Chang; Liang, Zhan; Glick, Ronald M; Morone, Natalia E; Chasens, Eileen R

    2016-01-01

    The purpose of this study was to report sleep quality from 4 weeks of auricular point acupressure that was designed for chronic low back pain and determine the relationship between pain intensity and sleep quality. Participants were randomized into the APA group (n = 30) or the sham-APA group (n = 31). At baseline assessment, 87% of the participants reported poor sleep quality. Participants who received APA had decreased daytime disturbance and improved global Pittsburgh Sleep Quality Index scores at end of intervention (EOI) and 1-month follow up compared to participants in the sham-APA group. For the APA group, both the sleep duration and wake after sleep onset decreased gradually during the 4-week APA (0.56% and 0.23% daily change, respectively). PMID:26244591

  17. [Posterior auricular muscle reflex in the study of the facial muscle function].

    Science.gov (United States)

    Parmigiani, F; Buratti, C

    1998-02-01

    To date the study of facial nerve function is based on just two tests: electroneurography (ENGH) and electromyography (EMG). Nevertheless neither of these tests gives reliable results until 8-10 days after onset of the paralysis. The authors have used an evoked auditory potential--more specifically the posterior auricular muscle reflex (PAMr) which is directly activated by the VII cranial nerve in the brainstem after acoustical stimulation. They first tested this method in normal subjects and later in patients with Bell's Palsy and the Ramsey Hunt Syndrome. The authors assert the predictive capacity of this test, in particular, underlining the clear-cut relationship between the time required for the paralysis to heal and the difference in side-to-side PAMr latency. While the sensitivity of the ENGH and PAMr tests are similar, PAMr makes staging of the evolution possible on the 2nd day after onset.

  18. Auricular Oedema and Dyshidrotic Eczema in a Patient with Acute Myeloid Leukaemia Treated with Cytarabine

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    K. Brandt

    2010-10-01

    Full Text Available Cytarabine is an effective drug in the treatment of haematological malignancies. The therapy is associated with various complications. Frequencies of dermatological side-effects range from 2–72% and occur most commonly after high-dose regimens. Although most cutaneous reactions are mild and resolve spontaneously within several days, they may result in an increased risk of infection and alterations in comfort. In some cases, severe life-threatening reactions have been reported. Here we describe the case of a patient with acute myeloid leukaemia, who developed severe exceptional skin toxicity in terms of auricular oedema and palmar dyshidrotic eczema after the application of low-dose cytarabine. Re-administration of the drug resulted in reduced skin toxicity during further cycles of chemotherapy. Negative epicutaneous patch-testing supported the existence of cytarabine-provoked toxicity.

  19. Clinical Outcomes of Osseointegrated Prosthetic Auricular Reconstruction in Patients With a Compromised Ipsilateral Temporoparietal Fascial Flap.

    Science.gov (United States)

    Zuo, Kevin J; Wilkes, Gordon H

    2016-01-01

    Patients with major ear deformities and associated compromise of the superficial temporal artery are poor candidates for autogenous ear reconstruction because of a tenuous ipsilateral temporoparietal fascial flap (TPFF). Osseointegrated prosthetic auricular reconstruction (OPAR) is an alternative to contralateral free TPFF microsurgical and autogenous reconstruction, but data on clinical outcomes are limited. The records of patients with ear loss or major deformity and a compromised ipsilateral TPFF who underwent OPAR from 1989 to 2013 were reviewed. Satisfaction was assessed using a questionnaire based on a 5 point Likert scale. Thirty-two patients (8 women, 24 men) with mean age 43.0 years (range, 10-70 years) underwent OPAR. The ipsilateral TPFF was compromised due to major trauma (13 patients), cancer extirpation (9), burn injury (4), previous harvest (4), arteriovenous malformation (1), or infection (1). All but 2 patients had an associated craniofacial defect, such as soft tissue deformity (87.5%), hearing loss (46.9%), or bony deformity (31.3%). The overall implant success rate was 88.6% at mean follow-up time of 7.6 years post-OPAR. Prosthesis wear averaged 12.2 hours/day and 6.6 days/week (80.5 hours/week). All 5 patients who experienced implant failures had received prior head and neck irradiation. With their prosthesis, 76.2% (16 patients) stated that their self-consciousness and self-esteem were "better" or "much better," whereas 85.7% (18 patients) stated that their self-image was "better" or "much better." All patients declared that they would undergo the treatment again. Osseointegrated prosthetic auricular reconstruction is a reliable option in this challenging population with high patient satisfaction. Patients with prior radiotherapy may have a higher chance of implant failure and would benefit from extended annual follow-up.

  20. Auricularia auricular polysaccharide-low molecular weight chitosan polyelectrolyte complex nanoparticles: Preparation and characterization

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    Wei Xiong

    2016-06-01

    Full Text Available Novel polyelectrolyte complex nanoparticles (AAP/LCS NPs were prepared in this study and these were produced by mixing negatively charged auricularia auricular polysaccharide (AAP with positively charged low molecular weight chitosan (LCS in an aqueous medium. The AAP was extracted and purified from auricularia auricular, and then characterized by micrOTOF-Q mass spectrometry, UV/Vis spectrophotometry, moisture analyzer and SEM. The yield, moisture, and total sugar content of the AAP were 4.5%, 6.2% and 90.12% (w/w, respectively. The AAP sample was water-soluble and exhibited white flocculence. The characteristics of AAP/LCS NPs, such as the particle size, zeta potential, morphology, FT-IR spectra, DSC were investigated. The results obtained revealed that the AAP/LCS NPs had a spherical shape with a diameter of 223 nm and a smooth surface, and the results of the FT-IR spectra and DSC investigations indicated that there was an electrostatic interaction between the two polyelectrolyte polymers. Bovine serum albumin (BSA, pI = 4.8 and bovine hemoglobin (BHb, pI = 6.8 were used as model drugs to investigate the loading and release features of the AAP/LCS NPs. The results obtained showed that the AAP/LCS NPs had a higher entrapment efficiency (92.6% for BHb than for BSA (81.5%. The cumulative release of BSA and BHb from AAP/LCS NPs after 24 h in vitro was 95.4% and 91.9%, respectively. The in vitro release demonstrated that AAP/LCS NPs provided a sustained release matrix suitable for the delivery of protein drugs. These studies demonstrate that AAP/LCS NPs have a very promising potential as a delivery system for protein drugs.

  1. La anticoagulación es necesaria cuando está indicada en pacientes con fibrilación auricular

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    Elibet Chávez-González

    2016-03-01

    Full Text Available En el año 2013 fue escrito un editorial titulado «Fibrilación auricular isquémica: cómo interpretar su fisiopatología y la decisión estratégica de tratamiento en torno a la arritmia». Permítanme comenzar de la misma forma, pues en aquel se habló sobre la anticoagulación en la fibrilación auricular (FA isquémica y en este momento, se pretende mencionar la necesidad de anticoagulación en la FA cuando es requerida, a propósito del artículo original de Merino Barrera et al., que se publica en este número de CorSalud.

  2. Auricular Acupressure for Managing Postoperative Pain and Knee Motion in Patients with Total Knee Replacement: A Randomized Sham Control Study

    OpenAIRE

    Ling-hua Chang; Chung-Hua Hsu; Gwo-Ping Jong; Shungtai Ho; Shiow-luan Tsay; Kuan-Chia Lin

    2012-01-01

    Background. Postoperative pain management remains a significant challenge for all healthcare providers. A randomized controlled trial was conducted to examine the adjuvant effects of auricular acupressure on relieving postoperative pain and improving the passive range of motion in patients with total knee replacement (TKR). Method. Sixty-two patients who had undergone a TKR were randomly assigned to the acupressure group and the sham control group. The intervention was delivered three times a...

  3. Effects of Electroacupuncture at Auricular Concha Region on the Depressive Status of Unpredictable Chronic Mild Stress Rat Models

    OpenAIRE

    Ru-Peng Liu; Ji-Liang Fang; Pei-Jing Rong; Yufeng Zhao; Hong Meng; Hui Ben; Liang Li; Zhan-Xia Huang; Xia Li; Ying-Ge Ma; Bing Zhu

    2013-01-01

    To explore new noninvasive treatment options for depression, this study investigated the effects of electroacupuncture (EA) at the auricular concha region (ACR) of depression rat models. Depression in rats was induced by unpredictable chronic mild stress (UCMS) combined with isolation for 21 days. Eighty male Wistar rats were randomly assigned into four groups: normal, UCMS alone, UCMS with EA-ACR treatment, and UCMS with EA-ear-tip treatment. Rats under inhaled anesthesia were treated once d...

  4. Reconstruction of Large Cheek Defect With/Without Sideburn Using Malar-Posterior Auricular-Cervico Flap.

    Science.gov (United States)

    Hayashi, Toshihiko; Yamamoto, Yuhei; Oyama, Akihiko; Funayama, Emi; Shichinohe, Ryuji; Murao, Naoki; Furukawa, Hiroshi

    2016-08-01

    The cheek region is the most common site for malignant tumor occurrence and the treatment of malignant skin tumor requires extensive local excision. Many previous reports have covered methods of reconstruction using local flaps for skin defects in the cheek region.In this article, we describe our experience with a surgical reconstruction using a new flap method for 8 patients with missing tissue in the cheek region. This flap is based on the concept of separately designing the flap with the 3 areas comprising the malar, posterior auricular, and cervical regions. We named the flap containing these 3 regions the malar-posterior auricular-cervico flap. Esthetically satisfactory outcomes were achieved in all cases.In conclusion, we recommend our malar-posterior auricular-cervico flap to reconstruct the tissue defects of approximately 20 to 40 cm after tumor excision in the cheek region. If preauricular skin is included in the design of this flap, the sideburn can be reconstructed using a part of the nape region with hair. PMID:26559648

  5. Localization of Auricular Projection Area of the Liver and Its Use in the Monitoring of Viral Hepatitis

    Institute of Scientific and Technical Information of China (English)

    Jan Z. Szopinski; Xiao Hong Teng; Georg P. Lochner; Tomasz Macura; Iwona Karcz-Socha; Anna Kasprzyk-Minkner; Krzysztof Kielan; Barbara Krupa-Jezierska; Dariusz J. Nasiek; Piotr Warakomski

    2006-01-01

    Background:Localization of auricular projection area of the liver and evaluation of its usefulness in the monitoring of viral hepatitis. Design, Patients and Setting: Comparative study of the degree of electrical rectification measured at various spots in the auricular concha region, in 19 inpatients with hepatitis B and 15 clinically healthy volunteers, at the Department of Infectious Diseases, Provincial Teaching Hospital,Tychy, Poland. Intervention: Evaluation of electrical rectification at various spots on the auricular concha using a "rectification ratio" that quantifies the degree of rectification (normal range:0-60%). Main outcome measure: The location of the skin area where a statistically significant difference existed between the rectification ratios was observed in patients (82±12% at the time of the 'peak period') versus controls (42±8%). Results: A location was identified on the ear auricle where the electrical rectification phenomenon demonstrated a dependence on the presence of hepatitis. Conclusions: Liver projection area exists on the ear auricle which is located within the region of cymba conchae, next to anthelix and the cavity of concha. The existence of viral hepatitis causes this skin area to show a higher degree of electrical rectification once the skin resistance 'breakthrough effect' has been induced. Evaluation of the rectification phenomenon of the liver projection area provides a method of non-invasive monitoring of viral hepatitis.

  6. Adenoid cystic carcinoma of the parotid gland: Anastamosis of the facial nerve with the great auricular nerve after radical parotidectomy

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    Bahadir Osman

    2008-01-01

    Full Text Available Adenoid cystic carcinoma of the parotid gland is a rare and slowly growing, but highly malignant tumor. Surgical resection of a malignant parotid tumor should include resection of the facial nerve when the nerve is involved in the tumor. Facial nerve reconstruction is required after nerve resection. A 14 year-old female presented with complaints of painless enlargement of the right parotid gland and facial asymmetry. Physical examination revealed a firm mass in the region of the parotid gland as well as right facial paralysis. Biopsy obtained from the mass showed an adenoid cystic carcinoma of the parotid gland. A radical parotidectomy with a modified radical neck dissection was carried out. Grafting material for the facial reconstruction was harvested from the great auricular nerve. The proximal main trunk and each distal branch of the facial nerve were coapted with the greater auricular nerve. The patient received radiotherapy after surgery and was seen to achieve grade IV facial function one year after surgery. Thus, the great auricular nerve is appropriate grafting material for coaptation of each distal branch of the facial nerve.

  7. Auricular Acupressure to Improve Menstrual Pain and Menstrual Distress and Heart Rate Variability for Primary Dysmenorrhea in Youth with Stress

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    Yu-Jen Wang

    2013-01-01

    Full Text Available Background. Dysmenorrhea and accompanying symptoms can have a negative impact on academic achievement, physical activity and functioning, and quality of life. Unfortunately, stress increases the sensitivity and severity of pain, activating sympathetic responses while inhibiting parasympathetic responses. Objective. This study used objective, physiological measurements to evaluate the effects of auricular acupressure on menstrual pain and menstrual distress in young college students with primary dysmenorrhea across two menstrual cycles. The aim was to determine if significant differences could be detected between the intervention and follow-up phases after controlling life stress. Design. A one-group experimental research design was used, and repeated measurements and followups were done. Thirty-two women completed questionnaires and physiological parameters were measured. Results. Significant differences between the intervention and follow-up phases were found for high frequency (HF and blood pressure on day 1 and no significant differences in menstrual pain and menstrual distress, heart rate variability, low frequency (LF, LF/HF ratio, or heart rate. Conclusion. Auricular acupressure effectively increases parasympathetic activity to maintain autonomic function homeostasis in young women with primary dysmenorrhea and may have a value in alleviating menstrual pain and menstrual distress in a high-stress life. Future studies should consider stress, stimulus dose of auricular acupressure, severity of menstrual pain, and a longitudinal research design.

  8. Chondrogenic potential of bone marrow–derived mesenchymal stem cells on a novel, auricular-shaped, nanocomposite scaffold

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    Kavi H Patel

    2013-12-01

    Full Text Available Reconstruction of the human auricle remains a challenge to plastic surgeons, and current approaches are not ideal. Tissue engineering provides a promising alternative. This study aims to evaluate the chondrogenic potential of bone marrow–derived mesenchymal stem cells on a novel, auricular-shaped polymer. The proposed polyhedral oligomeric silsesquioxane-modified poly(hexanolactone/carbonateurethane/urea nanocomposite polymer has already been transplanted in patients as the world’s first synthetic trachea, tear duct and vascular bypass graft. The nanocomposite scaffold was fabricated via a coagulation/salt-leaching method and shaped into an auricle. Adult bone marrow–derived mesenchymal stem cells were isolated, cultured and seeded onto the scaffold. On day 21, samples were sent for scanning electron microscopy, histology and immunofluorescence to assess for neocartilage formation. Cell viability assay confirmed cytocompatability and normal patterns of cellular growth at 7, 14 and 21 days after culture. This study demonstrates the potential of a novel polyhedral oligomeric silsesquioxane-modified poly(hexanolactone/carbonateurethane/urea scaffold for culturing bone marrow–derived mesenchymal stem cells in chondrogenic medium to produce an auricular-shaped construct. This is supported by scanning electron microscopy, histological and immunofluorescence analysis revealing markers of chondrogenesis including collagen type II, SOX-9, glycosaminoglycan and elastin. To the best of our knowledge, this is the first report of stem cell application on an auricular-shaped scaffold for tissue engineering purposes. Although many obstacles remain in producing a functional auricle, this is a promising step forward.

  9. por valores

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    Jazmín Díaz-Barrios

    2005-01-01

    Full Text Available La era actual se caracteriza por una búsqueda de la identidad del hombre, donde el pivote del cambio organizacional es el individuo; cambiar en este entorno depende, en gran medida, de los valores que imperen en la cultura de la organización. Este trabajo documental intenta identificar aquellos valores, condición sine-qua-non, para el logro de los objetivos de cambio y analizarlos a fin de determinar sus indicadores, con el objeto de presentar una herramienta a las organizaciones que les facilite adaptarse a los nuevos tiempos. Se encontró que los valores: Delegación, Comunicación, Colaboración, Participación y Aprendizaje, son esenciales en los cambios integrales de esta era. Se determinaron 20 indicadores de su presencia. Se concluye que con esta información cada ente puede elaborar instrumentos que le permitan saber si los valores requeridos están presentes y en caso contrario tomar decisiones que alineen a la organización alrededor de los valores humanistas planteados, incrementando así las posibilidades de éxito en el proceso de cambio y por ende, las posibilidades de supervivencia en esta nueva época.

  10. Use of Auricular Acupressure to Improve the Quality of Life in Diabetic Patients with Chronic Kidney Diseases: A Prospective Randomized Controlled Trial

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    Shaoqing Wang

    2014-01-01

    Full Text Available Background. Diabetic patients with chronic kidney disease (CKD suffer from low quality of life (QOL. We aim to assess the effectiveness of auricular acupressure for QOL improvement in these patients. Materials and Methods. Sixty-two participants were randomly assigned to an auricular or a control arm in a randomized controlled trial. Participants in the auricular arm were instructed to perform auricular acupressure 3–5 times per day for 3 months, when they were receiving conventional treatments. Participants in the control arm received conventional treatments only. The primary outcome was the summarized score of Kidney Disease and Quality of Life Short-Form (KDQOL-SF at 3 months after randomization. The secondary outcomes included the 36-Item Short Form Health Survey (SF-36, glycosylated hemoglobin (HbA1c, and estimated glomerular filtration rate (eGFR. Results. The summarized KDQOL differed significantly between the acupressure (76.6, 95% CI, 72.2 to 81.0 and the control group (61.8, 95% CI, 57.7 to 65.9. Similar results were found in the SF-36 scores. HbA1c and eGFR were not found to be significantly different between the arms and neither were the adverse events. Conclusion. Auricular acupressure was well tolerated in diabetic patients with chronic kidney diseases receiving hemodialysis. Future research is needed to confirm these results.

  11. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain.

    Science.gov (United States)

    Lin, Wei-Chun; Yeh, Chao Hsing; Chien, Lung-Chang; Morone, Natalia E; Glick, Ronald M; Albers, Kathryn M

    2015-01-01

    Background. Auricular point acupressure (APA) is a promising treatment for pain management. Few studies have investigated the physiological mechanisms of APA analgesics. Method. In this pilot randomized clinical trial (RCT), a 4-week APA treatment was used to manage chronic low back pain (CLBP). Sixty-one participants were randomized into a real APA group (n = 32) or a sham APA group (n = 29). Blood samples, pain intensity, and physical function were collected at baseline and after 4 weeks of treatment. Results. Subjects in the real APA group reported a 56% reduction of pain intensity and a 26% improvement in physical function. Serum blood samples showed (1) a decrease in IL-1β, IL-2, IL-6, and calcitonin gene-related peptide [CGRP] and (2) an increase in IL-4. In contrast, subjects in the sham APA group (1) reported a 9% reduction in pain and a 2% improvement in physical function and (2) exhibited minimal changes of inflammatory cytokines and neuropeptides. Statistically significant differences in IL-4 and CGRP expression between the real and sham APA groups were verified. Conclusion. These findings suggest that APA treatment affects pain intensity through modulation of the immune system, as reflected by APA-induced changes in serum inflammatory cytokine and neuropeptide levels. PMID:26170869

  12. A Randomized Clinical Trial of Auricular Point Acupressure for Chronic Low Back Pain: A Feasibility Study

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    Chao Hsing Yeh

    2013-01-01

    Full Text Available Objectives. This prospective, randomized clinical trial (RCT was designed to investigate the feasibility and effects of a 4-week auricular point acupressure (APA for chronic low back pain (CLBP. Methods. Participants were randomized to either true APA (true acupoints with taped seeds on the designated ear points for CLBP or sham APA (sham acupoints with taped seeds but on different locations than those designated for CLBP. The duration of treatment was four weeks. Participants were assessed before treatment, weekly during treatment, and 1 month following treatment. Results. Participants in the true APA group who completed the 4-week APA treatment had a 70% reduction in worst pain intensity, a 75% reduction in overall pain intensity, and a 42% improvement in disability due to back pain from baseline assessment. The reductions of worst pain and overall pain intensity in the true APA group were statistically greater than participants in the sham group (P<0.01 at the completion of a 4-week APA and 1 month followup. Discussion. The preliminary findings of this feasibility study showed a reduction in pain intensity and improvement in physical function suggesting that APA may be a promising treatment for patients with CLBP.

  13. Chondrocyte differentiation for auricular cartilage reconstruction using a chitosan based hydrogel.

    Science.gov (United States)

    García-López, J; Garciadiego-Cázares, D; Melgarejo-Ramírez, Y; Sánchez-Sánchez, R; Solís-Arrieta, L; García-Carvajal, Z; Sánchez-Betancourt, J I; Ibarra, C; Luna-Bárcenas, G; Velasquillo, C

    2015-12-01

    Tissue engineering with the use of biodegradable and biocompatible scaffolds is an interesting option for ear repair. Chitosan-Polyvinyl alcohol-Epichlorohydrine hydrogel (CS-PVA-ECH) is biocompatible and displays appropriate mechanical properties to be used as a scaffold. The present work, studies the potential of CS-PVA-ECH scaffolds seeded with chondrocytes to develop elastic cartilage engineered-neotissues. Chondrocytes isolated from rabbit and swine elastic cartilage were independently cultured onto CS-PVA-ECH scaffolds for 20 days to form the appropriate constructs. Then, in vitro cell viability and morphology were evaluated by calcein AM and EthD-1 assays and Scanning Electron Microscopy (SEM) respectively, and the constructs were implanted in nu/nu mice for four months, in order to evaluate the neotissue formation. Histological analysis of the formed neotissues was performed by Safranin O, Toluidine blue (GAG's), Verhoeff-Van Gieson (elastic fibers), Masson's trichrome (collagen) and Von Kossa (Calcium salts) stains and SEM. Results indicate appropriate cell viability, seeded with rabbit or swine chondrocyte constructs; nevertheless, upon implantation the constructs developed neotissues with different characteristics depending on the animal species from which the seeded chondrocytes came from. Neotissues developed from swine chondrocytes were similar to auricular cartilage, while neotissues from rabbit chondrocytes were similar to hyaline cartilage and eventually they differentiate to bone. This result suggests that neotissue characteristics may be influenced by the animal species source of the chondrocytes isolated. PMID:26119536

  14. Rapid development of auricular prosthesis using CAD and rapid prototyping technologies.

    Science.gov (United States)

    Subburaj, K; Nair, C; Rajesh, S; Meshram, S M; Ravi, B

    2007-10-01

    External ear defects can be corrected by surgery, but this may not be feasible for personal or medical reasons. Reconstructive solutions are a good alternative, but rely on the artistry and availability of the anaplastologist. A semi-automated methodology using computer-aided design (CAD) and rapid prototyping (RP) technologies was developed for auricular prosthesis development, and demonstrated in a real-life case. The correct geometry and position of the prosthesis were ensured by stacking the computed tomography scan images of the contralateral normal ear in reverse order, and joining them using a medical modelling software program. The CAD model of the remnant portion of the defective ear was subtracted from the model of the mirrored contralateral ear, using a haptic CAD system, to obtain the final geometry of the prosthesis. Polymer models were fabricated in RP systems, and used for making a corresponding mould. Medical grade silicone rubber of the appropriate colour was packed into the mould to fabricate the final ear prosthesis and fitted to the deficient side of the patient using medical grade adhesive. The computer-aided methodology gave a high level of accuracy in terms of shape, size and position of the prosthesis, and a significantly shorter lead time compared to the conventional (manual) technique. PMID:17822875

  15. Osseointegrated Implants: An Alternative Approach in Patients with Bilateral Auricular Defects due to Chemical Assault.

    Science.gov (United States)

    Mevio, Emilio; Mullace, Mauro; Facca, Luca; Schettini, Stefano

    2016-01-01

    Acid attacks committed as crimes of passion are unfortunately becoming far from infrequent occurrence. The injuries sustained in such attacks mainly involve the face and trunk, with the acid causing cutaneous and subcutaneous tissue burns that can result in permanent scarring, loss of the nose or external ear, and severe visual impairment. Different surgical solutions have been proposed for reconstruction of the auricle following loss of the ear through traumatic injury or cancer or in patients with congenital defects: surgical reconstruction may involve the insertion of an autogenous rib cartilage framework or the use of a porous polymer material inserted into an expanded postauricular flap. Reconstruction with rib cartilage has given good results but requires more than one surgical step and may be associated with adverse events involving both the donor site and the recipient site, while rejections of polymeric prostheses have been reported following their insertion into expanded postauricular flaps. The use of a titanium dowel-retained silicone prosthesis, in which the dowel is anchored to the temporal bone, is a surgical possibility, indicated particularly in cases of pinna resection due to tumour or auricular scarring following traumatic injury. PMID:27200202

  16. Osseointegrated Implants: An Alternative Approach in Patients with Bilateral Auricular Defects due to Chemical Assault

    Directory of Open Access Journals (Sweden)

    Emilio Mevio

    2016-01-01

    Full Text Available Acid attacks committed as crimes of passion are unfortunately becoming far from infrequent occurrence. The injuries sustained in such attacks mainly involve the face and trunk, with the acid causing cutaneous and subcutaneous tissue burns that can result in permanent scarring, loss of the nose or external ear, and severe visual impairment. Different surgical solutions have been proposed for reconstruction of the auricle following loss of the ear through traumatic injury or cancer or in patients with congenital defects: surgical reconstruction may involve the insertion of an autogenous rib cartilage framework or the use of a porous polymer material inserted into an expanded postauricular flap. Reconstruction with rib cartilage has given good results but requires more than one surgical step and may be associated with adverse events involving both the donor site and the recipient site, while rejections of polymeric prostheses have been reported following their insertion into expanded postauricular flaps. The use of a titanium dowel-retained silicone prosthesis, in which the dowel is anchored to the temporal bone, is a surgical possibility, indicated particularly in cases of pinna resection due to tumour or auricular scarring following traumatic injury.

  17. Tratamiento de estenosis sintomática de venas pulmonares secundaria a ablación por radiofrecuencia

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    Adolfo Ferrero Guadagnoli

    2014-08-01

    Full Text Available El aislamiento de las venas pulmonares mediante la aplicación de radiofrecuencia es un tratamiento efectivo de la fibrilación auricular. Una de las complicaciones potenciales y de mayor compromiso clínico de esta técnica invasiva es la estenosis de una o varias venas pulmonares. Esta complicación puede ser tratada mediante angioplastia con o sin colocación de stent, logrando una adecuada mejoría clínica, aunque con un alto índice de recurrencia por re-estenosis.

  18. Auricular reconstruction in patients with congenital microtia using homograft costal cartilage prepared by the Iranian Tissue Bank

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    Karimiyazdi A

    2008-12-01

    Full Text Available "nBackground: Several therapeutic modalities have been cited for patients with microtia. Recently there are several reports about using cadaveric homograft cartilage for some other purposes. The aim of this study was to assess the results of auricular reconstruct-tion in 10 patients (12 ears with congenital atresia using homograft rib cartilage from the Iranian Tissue Bank. "nMethods: We enrolled 10 patients with microtia who were referred to the Imam Khomeini Hospital from September 2006 to July 2007 for auricular reconstruction. The reconstruction was performed using a pre-shaped homograft(s of each patient's ear(s made by the Iranian Tissue Bank from the 6th, 7th and 8th costal cartilage according to the method of Marquette. In six patients, the second stage of reconstructive surgery was performed three months after the first stage. The patients were followed regarding the ear appearance, the dimensions of cartilage and tissue reaction. "nResults: The mean age of the patients was 11.08 (SD=5.57 years and the average duration of follow-up was 6.29 (SD=3.12 months. Eight cases had unilateral involvement (six right and two left, in addition to two cases of bilateral involvement. During the follow-up period, the appearance of the helix was satisfactory in 11 ears and the lobule in 10 ears. The height and width of the reconstructed auricles was an average of 1-2 millimeters different from the opposite ear. Erythema was the most common early complication. Late complications, including cartilage exposure and infection, were observed in one patient. "nConclusion: Auricular reconstruction using homograft costal cartilage in patients with microtia has promising results. The short term resorption can be ignored and significant early or late complications are infrequent.

  19. Auricular acupressure on specific points for hemodialysis patients with insomnia: a pilot randomized controlled trial.

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    Chuan Zou

    Full Text Available To assess the feasibility and acceptability of a randomized controlled trial compared auricular acupressure (AA on specific acupoints with AA on non-specific acupoints for treating maintenance hemodialysis (MHD patients with insomnia.Sixty three (63 eligible subjects were randomly assigned into either AA group received AA on specific acupoints (n=32, or sham AA (SAA group received AA on points irrelevant to insomnia treatment (n=31 for eight weeks. All participants were followed up for 12 weeks after treatments. The primary outcome was clinical response at eight weeks after randomization, defined as a reduction of Pittsburgh Sleep Quality Index (PSQI global score by 3 points and more.Fifty-eight (58 participants completed the trial and five dropped out. Twenty participants in AA group (62.5% and ten in SAA group (32.3% responded to the eight-week interventions (χ2 = 5.77, P = 0.02. PSQI global score declined 3.75 ± 4.36 (95%CI -5.32, -2.18 and 2.26 ± 3.89 (95%CI -3.68, -0.83 in AA group and SAA group respectively. Three participants died during the follow-up period. No evidence supported their deaths were related to the AA intervention. No other adverse event was observed.Feasibility and logistics of patient recruitment, randomization procedure, blinding approach, interventions application and outcome assessment had been tested in this pilot trial. The preliminary data appeared to show a favorable result on AA treatment. A full-scale trial is warranted.Chinese Clinical Trial Registry ChiCTR-TRC-12002272.

  20. Establishing an animal model for National Acupuncture Detoxification Association (NADA) auricular acupuncture protocol.

    Science.gov (United States)

    Kattalai Kailasam, Vasanth; Anand, Preeti; Melyan, Zara

    2016-06-15

    The use of opioids in the treatment of chronic pain has increased dramatically in the past few decades making them one of the most commonly prescribed medications in the US. However, long-term use of opioids is limited by development of tolerance (decreased antinociceptive efficacy) and opioid-induced hyperalgesia - paradoxical sensitization to noxious (hyperalgesia) and non-noxious (allodynia) stimuli. Novel adjunctive therapies are needed to increase the efficacy and prolong the duration of action of opioids in chronic pain treatment. Acupuncture is often used as an adjunct therapy for the treatment of symptoms induced by non-clinical use of opioids. The National Acupuncture Detoxification Association (NADA) auricular acupuncture protocol is the most common form of acupuncture treatment for substance abuse. The standardized, easy to use and virtually painless procedure make it an attractive complementary treatment option for patients suffering from opioid-induced adverse effects. Clinical trials designed to test the efficacy of the NADA protocol yielded contradictory results. The mechanism by which NADA acupuncture could serve as a successful treatment remains unknown. Therefore, establishing an animal model of NADA acupuncture can provide a tool for investigating the efficacy and cellular mechanisms of NADA treatment. Previous studies have shown that repeated morphine administration in rodents can produce locomotor sensitization and reduce analgesic potency of a challenge dose of morphine, indicating development of morphine tolerance. Here we show that NADA acupuncture treatment can both reduce morphine-induced locomotor sensitization and prevent the development of morphine tolerance in rats, thus validating a new model for NADA acupuncture studies. Our data provides support for evidence-based use of NADA acupuncture as a new adjunctive approach that can potentially improve the side-effect profile of morphine and other prescription opioids.

  1. Auricular Acupuncture and Cognitive Behavioural Therapy for Insomnia: A Randomised Controlled Study

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    L. Bergdahl

    2016-01-01

    Full Text Available Objective. The most effective nonpharmacological treatment for insomnia disorder is cognitive behavioural therapy-insomnia (CBT-i. However CBT-i may not suit everyone. Auricular acupuncture (AA is a complementary treatment. Studies show that it may alleviate insomnia symptoms. The aim of this randomised controlled study was to compare treatment effects of AA with CBT-i and evaluate symptoms of insomnia severity, anxiety, and depression. Method. Fifty-nine participants, mean age 60.5 years (SD 9.4, with insomnia disorder were randomised to group treatment with AA or CBT-i. Self-report questionnaires, the Insomnia Severity Index (ISI, Dysfunctional Beliefs and Attitudes about Sleep scale (DBAS-16, Epworth Sleepiness Scale (ESS, and Hospital Anxiety and Depression scale (HAD, were collected at baseline, after treatment, and at 6-month follow-up. A series of linear mixed models were performed to examine treatment effect over time between and within the groups. Results. Significant between-group improvements were seen in favour of CBT-i in ISI after treatment and at the 6-month follow-up and in DBAS-16 after treatment. Both groups showed significant within-group postintervention improvements in ISI, and these changes were maintained six months later. The CBT-i group also showed a significant reduction in DBAS-16 after treatment and six months later. Conclusions. Compared to CBT-i, AA, as offered in this study, cannot be considered an effective stand-alone treatment for insomnia disorder. The trial is registered with ClinicalTrials.gov NCT01765959.

  2. Effect of laser acupuncture and auricular acupressure in a child with trismus as a sequela of medulloblastoma.

    Science.gov (United States)

    Ferreira, Danielly Cunha Araújo; De Rossi, Andiara; Torres, Carolina Paes; Galo, Rodrigo; Paula-Silva, Francisco Wanderley Garcia; Queiroz, Alexandra Mussolino de

    2014-04-01

    In several countries the most common cause of death in young people is cancer. Patients with head and neck cancer often have complications after cancer treatment. Radiation therapy can cause oral trismus, which is related to high doses of radiation. Although acupuncture is reported to be effective and is widely used for the treatment of peripheral facial paralysis by promoting an improvement of motor functions, few reports in the literature demonstrate its effectiveness. We report a case in which the symptoms of a patient with facial paralysis after surgical cancer treatment associated with chemotherapy and radiotherapy improved after laser treatment at acupuncture points. Ten weekly sessions of laser therapy were conducted, using the Twin laser device, applied to systemic acupuncture points (LR3, LI4, LI18, LI19, LI20, SI17, SI19, ST4, ST6, ST7, GV20), together with 10 weekly sessions of auricular acupressure. Significant improvement of the trismus was seen, confirmed by the increase in mouth opening from 33.26 to 53.3 mm. The patient's family also noted reduced anxiety and hyperactivity. These results suggest that laser acupuncture and auricular acupressure for trismus and facial paralysis following cancer treatment is worth further investigation. PMID:24384541

  3. Auricular Acupressure for Managing Postoperative Pain and Knee Motion in Patients with Total Knee Replacement: A Randomized Sham Control Study

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    Ling-hua Chang

    2012-01-01

    Full Text Available Background. Postoperative pain management remains a significant challenge for all healthcare providers. A randomized controlled trial was conducted to examine the adjuvant effects of auricular acupressure on relieving postoperative pain and improving the passive range of motion in patients with total knee replacement (TKR. Method. Sixty-two patients who had undergone a TKR were randomly assigned to the acupressure group and the sham control group. The intervention was delivered three times a day for 3 days. A visual analog scale (VAS and the Short-Form McGill Pain Questionnaire were used to assess pain intensity. Pain medication consumption was recorded, and the knee motion was measured using a goniometer. Results. The patients experienced a moderately severe level of pain postoperatively (VAS 58.66 ± 20.35 while being on the routine PCA. No differences were found in pain scores between the groups at all points. However, analgesic drug usage in the acupressure group patients was significantly lower than in the sham control group (<0.05, controlling for BMI, age, and pain score. On the 3rd day after surgery, the passive knee motion in the acupressure group patients was significantly better than in the sham control group patients (<0.05, controlling for BMI. Conclusion. The application of auricular acupressure at specific therapeutic points significantly reduces the opioid analgesia requirement and improves the knee motion in patients with TKR.

  4. Comparison of Body, Auricular, and Abdominal Acupuncture Treatments for Insomnia Differentiated as Internal Harassment of Phlegm-Heat Syndrome: An Orthogonal Design

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    Yue Jiao

    2015-01-01

    Full Text Available Objective. To identify the optimum treatment protocol for insomnia among auricular, body, and abdominal needling methods. Methods. A three-factor (3 needling protocols and three-level experimental scheme was designed based on orthogonal method. 54 patients of insomnia differentiated as internal harassment of phlegm-heat syndrome were given two courses of acupuncture treatment (each with 20 times of acupuncture. The therapeutic effects were evaluated by comparing the Pittsburgh sleep quality index (PSQI, Hamilton Depression Scale (HAMD scores, and Hamilton Anxiety Scale (HAMA scores of patients before treatment, after one course of treatment, and after two courses of treatment as well as one month after treatment. Results. Body, auricular, and abdominal acupuncture treatments all alleviated symptoms of insomnia, depression, and anxiety, but body and auricular acupuncture had stronger therapeutic effects. Conclusions. Body acupuncture at basic points shall be given priority in protocol selection for insomnia. The second-best choice is auricular acupuncture with basic points combined with points based on Traditional Chinese Medicine (TCM theories. Abdominal needling with very quick effect can be an alternative protocol with basic points combined with syndrome differentiation points.

  5. Comparison of Body, Auricular, and Abdominal Acupuncture Treatments for Insomnia Differentiated as Internal Harassment of Phlegm-Heat Syndrome: An Orthogonal Design.

    Science.gov (United States)

    Jiao, Yue; Han, Ying; Li, Xin; Fang, Yi-Gong; Liu, Zhao-Hui; Zhou, Wen-Na; Zhou, Jin-Cao; Wu, Zhong-Chao; Yang, Jin-Hong; Li, Shao-Yuan; Meng, Fan-Ying; Xu, Wei-Wei

    2015-01-01

    Objective. To identify the optimum treatment protocol for insomnia among auricular, body, and abdominal needling methods. Methods. A three-factor (3 needling protocols) and three-level experimental scheme was designed based on orthogonal method. 54 patients of insomnia differentiated as internal harassment of phlegm-heat syndrome were given two courses of acupuncture treatment (each with 20 times of acupuncture). The therapeutic effects were evaluated by comparing the Pittsburgh sleep quality index (PSQI), Hamilton Depression Scale (HAMD) scores, and Hamilton Anxiety Scale (HAMA) scores of patients before treatment, after one course of treatment, and after two courses of treatment as well as one month after treatment. Results. Body, auricular, and abdominal acupuncture treatments all alleviated symptoms of insomnia, depression, and anxiety, but body and auricular acupuncture had stronger therapeutic effects. Conclusions. Body acupuncture at basic points shall be given priority in protocol selection for insomnia. The second-best choice is auricular acupuncture with basic points combined with points based on Traditional Chinese Medicine (TCM) theories. Abdominal needling with very quick effect can be an alternative protocol with basic points combined with syndrome differentiation points. PMID:26640498

  6. PRE AURICULAR SINUS: A CLINICAL ANALYSIS OF 62 CASES AND REVIEW OF ITS MICRO SURGICAL MANAGEMENT

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    Indira Devi

    2014-11-01

    Full Text Available INTRODUCTION: Pre auricular sinus (PAS is a common clinical finding seen in the ENT outpatient department. The patients complain only when it is infected, when cheesy material is extruded often form the aural pit. Initial control of infection, incision and drainage of the abscess becomes the primary step in its treatment. This is followed by the attempt to excise the tract to avoid recurrence of cellulitis and abscess. Simple sinectomy leads to recurrence; hence requires microscopic dissection and excision. The present study attempts to analyze the genetic penetration, incidence in various socio-economic groups and at the same time to review the micro surgical management. MATERIALS AND METHODS: 62 patients diagnosed with Preauricular sinus attending department of ENT, GGH; Kurnool were analyzed for genetic role in its etiology in addition to the prevalence of the condition according to the social and economic status. Thorough clinical examination and where necessary audiological evaluation to rule out innner ear pathology was done. Bacteriological study was done subjecting the pus and material extruded from the sinus pits. After a surgical profile all the patients except 4 were subjected to Total excision of the sinus tract using circular incision around the sinus pit and extending it posteriorly around the root of the pinna. All were followed for a period of 12 months to evaluate recurrence rate, Infection rate and wound dehiscence. OBSERVATIONS: Among the 62 patients there were 37 females and 25 males. The patient’s age range was from 9 months to 36 years. 18 patients had undergone surgery at least once before presenting in this study. The commonest organism isolated was Staph aureus followed by bacillus fragilis and pseudomonas aeroginosa. Incomplete gene penetration was noted in 34 out of the 62 patients, as PAS was noticed in parents, siblings and grandparents. Follow up showed no recurrence over 1 year. CONCLUSIONS: PAS is a congenital

  7. Anticoagulación en fibrilación auricular y antiagregación en diabetes mellitus tipo 2: ¿Cómo lo hacemos?

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    M.P. Arroyo

    2007-04-01

    Full Text Available Fundamento: A pesar de la evidencia sobre el interés de anticoagular en Fibrilación Auricular (FA y antiagregar a los diabéticos (DM tipo 2, las referencias nacionales e internacionales hablan de un bajo nivel de asunción de esos criterios en la práctica. Navarra no dispone de estudios publicados sobre estos aspectos. Material y métodos: Estudio descriptivo transversal. Población: consulta de atención primaria (1600 personas 15 años. Criterios de inclusión: pacientes con diagnóstico de FA/ con diagnóstico de DM tipo 2 mayores de 40. Variables: edad y sexo, criterios de FA con alto riesgo embólico (6% anual y factores de RCV en DM2. Recogida de datos: en registro informatizado de Organitation and Management Information (OMI. Análisis: (estudiado el universo poblacional, resultados en números absolutos y porcentajes. Resultados: Veinticinco personas con diagnóstico de FA crónica (14 mujeres y 11 hombres, edad media 78,36 años; 22 (81,8% presentan alto riesgo embólico. Hubo contraindicaciones en 4 casos. Los diabéticos tipo 2 suman 69 personas (29 mujeres y 40 varones, edad media 68,57 años. En prevención primaria (PP hay 16 (23,1%, en prevención secundaria (PS 26 (37,3%, y no llevan tratamiento antiagregante 27 (39,1%. Existe contraindicación en 8 casos y serían 14 (20,2% los pacientes susceptibles de intervención. Conclusiones: - Los resultados de tratamiento anticoagulante oral (TAO en FA de alto riesgo superan las referencias contratadas. - La PP con DM2 con cifras similares a otros estudios; se detecta un campo de mejora. - Debemos solicitar la opinión del paciente e individualizar estas terapias. - Importante responsabilidad del médico de familia en la prevención cardiovascular de los pacientes afectados por estos procesos.

  8. Three-dimensional precise orientation of bilateral auricular trial prosthesis using a facebow for a young adult with Crouzon syndrome.

    Science.gov (United States)

    Rathee, Manu; Tamrakar, Amit Kumar; Kundu, Renu; Yunus, Nadeem

    2014-01-01

    Facial deformity can be debilitating, especially in the psychological and cosmetic aspects. Although surgical correction or replacement of deformed or missing parts is the ideal treatment, prosthetic replacement serves the purpose in case of surgical limitations. Prosthetic rehabilitation of a missing auricle is an acceptable option as it provides better control over the tortuous anatomical shape and shade of the missing portion. Improper spatial orientation of the prosthetic ear on the face can damage the results of even the most aesthetic prosthesis. This case report describes a simple and innovative method for precise spatial orientation of auricular trial prosthesis using a facebow and custom-made adjustable mechanical retention design using stainless steel wire. PMID:25096652

  9. A Curative Effect Study on Auricular Seed-pressing Therapy Used for Patients with Insomnia%耳穴贴压治疗失眠症患者的疗效观察

    Institute of Scientific and Technical Information of China (English)

    臧镭镭; 胡虹

    2014-01-01

    Objective To observe the effect of auricular seed-pressing for patients with insomnia. Methods 120 patients with insomnia were randomly divided into three groups, each group of 40 cases, are treated with single medication, single auricular seed-pressing and combined with auricular seed-pressing and medication. Results Combined with auricular seed-pressing and medication group in all aspects of indicators are better than the single medication group and single auricular seed-pressing group. Conclusion Combined with auricular seed-pressing and medication treats the insomnia curative effect to be remarkable.%目的:观察耳穴贴压治疗失眠症患者的疗效。方法失眠症患者120例随机分为三组。每组40例,分别给予单纯服药,单纯耳穴贴压及服药联合耳穴贴压。结果服药联合耳穴贴压组在各方面指标均优于单纯服药组和单纯耳穴贴压组。结论服药联合耳穴贴压治疗失眠症疗效显著。

  10. HOSPITALIZACIONES EVITABLES POR INSUFICIENCIA CARDÍACA. VARIABLES RELACIONADAS

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    Victoria Ruiz-Romero

    2016-01-01

    Full Text Available Los ingresos hospitalarios evitables por insuficiencia cardiaca (IC son un problema para los sistemas de salud, consumen recursos, generan morbilidades adicionales y alta mortalidad. El objetivo del estudio fue conocer los factores de riesgo de las personas hospitalizadas por insuficiencia cardiaca. Métodos: Se constituyó un grupo con médicos de atención primaria y hospitalaria. Se realizaron auditorías de las historias clínicas de 110 pacien - tes de la poblacion de la comarca del Aljarafe con mayores tasas de ingreso por insuficiencia cardiaca y estudio descriptivo y comparativo con T-Student y U-Mann Whitney para cuantitativas y λ 2 y Fisher para cualitativas. Resultados: Los pacientes que ingresaron por IC tenían 78,1 años (SD: 9,56 de media; 73 (66,4% fueron mujeres; un Índice Barthel de 45,0 de media; un 53,5% con grado III de la NYHA y 17 (15,5% institucionaliza - dos. El 70% presentaban 3-5 comorbilidades, hipertensión (87,3%, dislipe - mia (60,0% diabetes (57,3%, enfermedad renal crónica (56,4%, anemia (53,2% o fibrilación auricular (52,7%. Fallecieron al ingreso 23 (20,9% pacientes. Conclusiones: Los ingresos se dieron en personas mayores con múl - tiples enfermedades (hipertensión, diabetes, EPOC, enfermedad renal y escasa capacidad para actividades básicas de la vida diaria. El fallecimiento hospitalario se asoció a edad avanzada, ser mujer, menor uso de betabloqueantes y la no inclusión del paciente en el proceso asistencial.

  11. Auricular or body acupuncture: which one is more effective in reducing abdominal fat mass in Iranian men with obesity: a randomized clinical trial

    OpenAIRE

    Darbandi, Mahsa; Darbandi, Sara; Owji, Ali Akbar; Mokarram, Pooneh; Mobarhan, Majid Ghayor; Fardaei, Majid; Zhao, Baxiao; Abdi, Hamid; Nematy, Mohsen; Safarian, Mohammad; Parizadeh, Mohammad Reza; Dabbaghmanesh, Mohammad Hossein; Abbasi, Parisa; FERNS, Gordon

    2014-01-01

    Background The prevalence of abdominal obesity is on the rise worldwide. Previous studies have indicated the higher diagnostic value of body fat distribution pattern compared with general body in abdominal obesity assessments. Several non-pharmacological methods have been suggested for obesity management, of which acupuncture has gained a great deal of research interest with promising results. This study aimed to comparatively evaluate the effects of conventional auricular and body electroacu...

  12. Comparison of Body, Auricular, and Abdominal Acupuncture Treatments for Insomnia Differentiated as Internal Harassment of Phlegm-Heat Syndrome: An Orthogonal Design

    OpenAIRE

    Yue Jiao; Ying Han; Xin Li; Yi-gong Fang; Zhao-hui Liu; Wen-na Zhou; Jin-cao Zhou; Zhong-chao Wu; Jin-hong Yang; Shao-yuan Li; Fan-ying Meng; Wei-wei Xu

    2015-01-01

    Objective. To identify the optimum treatment protocol for insomnia among auricular, body, and abdominal needling methods. Methods. A three-factor (3 needling protocols) and three-level experimental scheme was designed based on orthogonal method. 54 patients of insomnia differentiated as internal harassment of phlegm-heat syndrome were given two courses of acupuncture treatment (each with 20 times of acupuncture). The therapeutic effects were evaluated by comparing the Pittsburgh sleep quality...

  13. Efficacy and safety of auricular point acupressure treatment for gastrointestinal dysfunction after laparoscopic cholecystectomy: study protocol for a randomized controlled trial

    OpenAIRE

    Tan, Yuhua; Zhao, Ye; He, Tian; Ma, Yueshen; Cai, Wang; Wang, Yandong

    2016-01-01

    Background Practitioners of traditional Chinese medicine know that auricular point acupressure (APP) using vaccaria seeds on the large intestine point (CO7) has a significant effect on postoperative gastrointestinal dysfunction. A standardized, clinical, research design will transform this clinical experience into scientific evidence, thus providing a basis to promote the wider use of this therapy. We aim to carry out a double-blind, randomized, controlled trial (RCT) to evaluate the efficacy...

  14. 手法按摩配合耳穴治疗失眠症临床观察%Clinical Observation on Manipulation Combined with Auricular Therapy for Insomnia

    Institute of Scientific and Technical Information of China (English)

    蔡献芬

    2013-01-01

      目的:观察手法按摩配合耳穴治疗失眠症的临床疗效。方法:采用手法按摩配合耳穴磁珠治疗31例失眠患者,2个疗程后评价疗效。结果:痊愈6例,显效16例,有效8例,无效1例,总有效率96.8%,愈显率达71.0%。结论:手法按摩配合耳穴治疗失眠症疗效显著,无副作用,值得临床推广应用。%Objective:To observe the efficacy of treating insomnia by manipulation combined with auricular therapy. Methods:31 cases of insomnia patients were all treated by manipulation combined with auricular therapy, and evaluated the efficacy after 2 courses of treatment. Results:6 cases were cured, 16 cases had marked effect, 8 cases were effective, and 1 cases was ineffective, the total effective rate was 96.8%, the cured and marked effect rate was 71.0%. Conclusion:Manipulation combined with auricular therapy has significant efficacy and no side effects, deserves clinical pro-motion and application.

  15. Dan Zhi Xiao Yao Yin Combined With Auricular-Point-Pressing for Treatment of Optic Atrophy - A Clinical Observation of 51 Cases

    Institute of Scientific and Technical Information of China (English)

    杨海燕

    2004-01-01

    To evaluate the therapeutic effect of Dan Zhi Xiao Yao Yin (丹栀消遥饮 Decoction of Moutan Bark and Capejasmine) combined with auricular-point- pressing therapy for treatment of optic atrophy. The visual acuity and visual field was observed in the 51 cases (58 eyes) from the treatment group that were treated with Dan Zhi Xiao Yao Yin combined with auricular-point-pressing therapy and the 43 cases (49 eyes)from the control group that were treated with routine western drugs at the end of the trial (60 days). The effective rates of increase in visual acuity obtained in the treatment and the control groups were 79.3% and 44.89% respectively and enlargement in visual field were 61.9% and 22.6% respectively. Statistical analysis showed that there were significant differences between two groups (P<0.05). The therapeutic effect of Dan Zhi Xiao Yao Yin combined with auricular-point -pressing therapy in increasing the visual acuity and enlarging the visual field was superior to that of the routine western drugs.

  16. Bloqueo auriculoventricular transitorio de primer grado en paciente con poliintoxicación por drogas de abuso y etanol: The Holiday Heart Syndrome

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    P Poveda Velázquez

    2014-01-01

    Full Text Available Las intoxicaciones por alcohol y drogas de abuso son una causa frecuente de consulta en los Servicios de Urgencias. Las alteraciones electrocardiográficas y las arritmias debidas a la ingesta de alcohol se conocen como Holiday Heart Syndrome. Este síndrome se define como la presencia de alteraciones del ritmo o de la conducción cardiaca asociadas al consumo de alcohol que revierten tras la intoxicación y que se producen en una persona sin enfermedad cardiaca conocida. La alteración más común es la fibrilación auricular. Se presenta el caso de una paciente joven que ingresa en urgencias por intoxicación por alcohol y diferentes drogas y que presentaba un bloqueo auriculoventricular de primer grado transitorio. Se discute el posible efecto causal de las drogas y del alcohol en los cambios electrocardiográficos observados en esta paciente.

  17. Effects of different nerve autografts on greater auricular nerve deficit in rabbits

    Institute of Scientific and Technical Information of China (English)

    Shaozong Chen

    2007-01-01

    BACKGROUND: Autograft is commonly used to repair nerve deficit. Usually, the choice of donor nerves is based on their similarities in form and structures to the injured nerves. For the reason, the cutaneous antebrachii lateralis nerve is currently considered the most suited for digital nerve repair. OBJECTIVE: To compare early nerve regeneration after transplantation of three different autografts: the greater auricular nerve (CAN), the saphenous nerve (SN) and the lateral femoral cutaneous nerve (LFCN). DESIGN: Observational contrast study. SETTING: Department of Plastic Surgery and Burns, Tangdu Hospital, Fourth Military Medical University of Chinese PLA.MATERIALS: A total of 42 New Zealand rabbits, of both genders, 12 - 14 months old and weighing 2.0 -2.5 kg, were used in this study. In addition, Moller-spetra 900 operating microscope (Germany), Olympus BX 51 microscope, DP 70 image collecting System (Japan), BL-420E+ Biologic function testing System (China), JEM-100 electron microscope (Japan), Reichet-JunG820 Cryostat (Swiss), and Libror-AEG-120 precision analytical Balance (Japan) were also used in this study.METHODS: The experiment was carried out in the Department of Plastic Surgery and Burns, Tangdu Hospital, Fourth Military Medical University of Chinese PLA from April to November 2005. After anaesthesia, the GAN were dissected bilaterally and a 1.2 cm deficit was made in each nerve. The animals were randomly divided into three groups, including GAN group, SN group and LFCN group with 14 in each group. ①Nerve pinch test: At 1,2, and 4 weeks after operation, three animals in each group were tested. The nerve grafts, along with the proximal and distal GAN segments were exposed and pinched with microsurgical forceps in distal-proximal orientations. The distance between the proximal anastomosis site and the most distal point, where the pinch evoked an ear contraction response, was measured as distance of nerve regeneration. ②Computer image analysis: At 4

  18. Auricular Electroacupuncture Reduced Inflammation-Related Epilepsy Accompanied by Altered TRPA1, pPKCα, pPKCε, and pERk1/2 Signaling Pathways in Kainic Acid-Treated Rats

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    Yi-Wen Lin

    2014-01-01

    Full Text Available Background. Inflammation is often considered to play a crucial role in epilepsy by affecting iron status and metabolism. In this study, we investigated the curative effect of auricular acupuncture and somatic acupuncture on kainic acid- (KA- induced epilepsy in rats. Methods. We established an epileptic seizure model in rats by KA (12 mg, ip. The 2 Hz electroacupuncture (EA was applied at auricular and applied at Zusanli and Shangjuxu (ST36-ST37 acupoints for 20 min for 3 days/week for 6 weeks beginning on the day following the KA injection. Results. The electrophysiological results indicated that neuron overexcitation occurred in the KA-treated rats. This phenomenon could be reversed among either the auricular EA or ST36-ST37 EA treatment, but not in the sham-control rats. The Western blot results revealed that TRPA1, but not TRPV4, was upregulated by injecting KA and could be attenuated by administering auricular or ST36-ST37 EA, but not in the sham group. In addition, potentiation of TRPA1 was accompanied by increased PKCα and reduced PKCε. Furthermore, pERK1/2, which is indicated in inflammation, was also increased by KA. Furthermore, the aforementioned mechanisms could be reversed by administering auricular EA and could be partially reversed by ST36-ST37 EA. Conclusions. These results indicate a novel mechanism for treating inflammation-associated epilepsy and can be translated into clinical therapy.

  19. Auricular Point Acupressure to Manage Chronic Low Back Pain in Older Adults: A Randomized Controlled Pilot Study

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    Chao Hsing Yeh

    2014-01-01

    Full Text Available This prospective, randomized clinical trial (RCT pilot study was designed to (1 assess the feasibility and tolerability of an easily administered, auricular point acupressure (APA intervention and (2 provide an initial assessment of effect size as compared to a sham treatment. Thirty-seven subjects were randomized to receive either the real or sham APA treatment. All participants were treated once a week for 4 weeks. Self-report measures were obtained at baseline, weekly during treatment, at end-of-intervention (EOI, and at a 1-month follow-up. A dropout rate of 26% in the real APA group and 50% in the sham group was observed. The reduction in worst pain from baseline to EOI was 41% for the real and 5% for the sham group with a Cohen’s effect size of 1.22 P<0.00. Disability scores on the Roland Morris Disability Questionnaire (RMDQ decreased in the real group by 29% and were unchanged in the sham group (+3% P<0.00. Given the high dropout rate, results must be interpreted with caution; nevertheless, our results suggest that APA may provide an inexpensive and effective complementary approach for the management of back pain in older adults, and further study is warranted.

  20. Effects of Electroacupuncture at Auricular Concha Region on the Depressive Status of Unpredictable Chronic Mild Stress Rat Models

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    Ru-Peng Liu

    2013-01-01

    Full Text Available To explore new noninvasive treatment options for depression, this study investigated the effects of electroacupuncture (EA at the auricular concha region (ACR of depression rat models. Depression in rats was induced by unpredictable chronic mild stress (UCMS combined with isolation for 21 days. Eighty male Wistar rats were randomly assigned into four groups: normal, UCMS alone, UCMS with EA-ACR treatment, and UCMS with EA-ear-tip treatment. Rats under inhaled anesthesia were treated once daily for 14 days. The results showed that blood pressure and heart rate were significantly reduced in the EA-ACR group than in the UCMS alone group or the EA-ear-tip group. The open-field test scores significantly decreased in the UCMS alone and EA-ear-tip groups but not in the EA-ACR group. Both EA treatments downregulated levels of plasma cortisol and ACTH in UCMS rats back to normal levels. The present study suggested that EA-ACR can elicit similar cardioinhibitory effects as vagus nerve stimulation (VNS, and EA-ACR significantly antagonized UCMS-induced depressive status in UCMS rats. The antidepressant effect of EA-ACR is possibly mediated via the normalization of the hypothalamic-pituitary-adrenal (HPA axis hyperactivity.

  1. 带蒂筋膜管的耳大神经移植治疗面神经缺失性损伤%Treating defective damage of facial nerve with great auricular nerve grafting covered by pediculated fascial tube

    Institute of Scientific and Technical Information of China (English)

    蒋立新

    2002-01-01

    Objective To study the curative effect of grafting great auricular nerve with pediculated fascial tube in defective damage of facial nerve.Method All the patients in the study were treated by grafting great auricular nerve which was covered by pediculated fascial tube near facial nerve trunk.Result The 3 otogenic fascial paralysis patients had grade III recovery of facial nerve function(30% ~ 38% ) 2.0 to 2.5 years after the nerve grafting operation; 2 post- traumatic facial paralysis patients had grade II recovery of facial nerve function (69% ~ 71% ) 2.5 to 3.5 years after the nerve grafting operation.Conclusion The grafting of pediculated fascial tube surrounded great auricular nerve can provide a biological environment with excellent blood supply for the plerosis and regeneration of nerves and can accelerate the functional recovery of nerves after the nerve grafting.

  2. RAPD analysis of genetic diversity of nine strains of Auricularia auricular cultivated in Heilongjiang Province%黑龙江省黑木耳9个栽培菌株遗传多样性的RAPD分析

    Institute of Scientific and Technical Information of China (English)

    李玲; 李杰; 邹丽; 白素英; 牛黎明; 马玉堃

    2007-01-01

    本文对黑龙江省9个黑木耳 (Auricularia auricular)栽培菌株进行PCR-RAPD扩增和群体聚类分析, 在40个10bp随机引物中,筛选出13个引物.结果表明:黑木耳不同栽培菌株之间存在着丰富的多态性(96.05%).用引物27和引物46的RAPD扩增指纹能有效分辨9个不同菌株的基因型,这一结果有助于在早期对黑木耳栽培菌株进行快速鉴别,为规范鉴别食用菌菌种混乱的局面提供科学依据.%Polymorphism of nine strains (CF05, CF09, 29, 916, AU9, Chang10, Chang7, 8808 and AU. Japanese) of A. auricular cultivated in Heilongjiang Province were analyzed by RAPD (Random Amplication polymorphic DNA). Thirteen primers were selected from forty PCR primers with 10bp long random primer. The results showed that nine strains of A. auricular have a high level of genetic diversity and the percentage of DNA polymorphic was 96.05. The genotypes of 9 strains of Auricularia auricular were identified by the fingerprints from primer 27 and primer 46 by RAPD analysis. The results are helpful for quickly identifying strains of A. auricular in its early breeding time, and also provides a powerful theoretic basis to differentiate strains (Auricularia auricular) whose morphology is very similar in breeding programs of edible fungus.

  3. Estenosis de venas pulmonares post ablación por radiofrecuencia

    Directory of Open Access Journals (Sweden)

    Marcelo Guzzi

    2011-06-01

    Full Text Available Es importante estar atento ante la aparición de síntomas respiratorios luego de la realización de un procedimiento de ablación por radiofrecuencia en el tratamiento de la fibrilación auricular, pues la estenosis de venas pulmonares (EVP tiene una incidencia de entre 1 y 3% y puede aparecer hasta en los dos años posteriores al procedimiento1. Presentamos el caso de un paciente de 41 años de sexo masculino, que ingresó por un cuadro de hemoptisis y toracodinia de tres semanas de evolución, con antecedente de ablación por radiofrecuencia 6 meses antes de la admisión. La angiotomografía no evidenció tromboembolismo pulmonar (TEP y la angiorresonancia detectó hipoperfusión deI lóbulo superior del pulmón izquierdo (LSI. Debido a los antecedentes de ablación se solicitó angiotomografía de venas pulmonares, que evidenció estenosis de la vena del LSI. Se realizó estudio hemodinámico con dilatación y colocación de stent.

  4. Operative design of primary total auricular reconstruction with cephalic SMAS island flaps%头部SMAS岛状瓣Ⅰ期全耳郭再造的手术设计

    Institute of Scientific and Technical Information of China (English)

    匡建国; 王乃佐; 楚建军

    2012-01-01

    Objective To investigate the feasibility of many kinds of designs with insular cephalic-SMAS flaps for covering auricular framework. Methods According to the template of tissue flaps drawn by CT and the blood supply of the cephalic-SMAS, the SMAS island flaps pedicled with the frontal and parietal branch of superficial temporal vessel and occipital branch of retro auricular vessel were designed for simulating primarily total auricular reconstruction on five cadaver specimens. Results (1) The SMAS island flaps designed by CT three-dimensional measurement method can be used for covering auricular framework well. (2) Ihree different kinds of SMAS island flaps were designed for covering auricular framework, and primary total auricular reconstructions were simulated. Conclusion (1) The SMAS island flaps designed by CT three-dimensional measurement method can meet requirements of covering auricular framework. (2) Two kinds of SMAS island flaps can be designed on the same side pedicled with the parietal (frontal) branch of superficial temporal vessels and occipital branch of retroauricular vessels, and that can offer multiple choices for covering auricular frameworks.%目的 探讨设计多种头部SMAS岛状瓣覆盖耳支架的可行性,为SMAS岛状瓣Ⅰ期全耳郭再造的手术设计提供理论依据.方法 依照CT三维测量法测算出耳支架覆盖组织瓣模板和头部SMAS的血供来源,在5例尸体标本上分别以颞浅血管顶支、颞浅血管额支和耳后血管枕支为蒂设计SMAS岛状瓣,模拟Ⅰ期全耳郭再造.结果 ①运用CT三维测量法设计的SMAS岛状瓣,可较好地覆盖耳郭支架.②设计出3种不同的SMAS岛状瓣覆盖耳支架,完成Ⅰ期全耳郭再造的手术模拟.结论 ①以CT三维测量法测算出的SMAS岛状瓣能够满足覆盖耳支架的要求.②在同侧分别以颞浅血管顶支(或额支)和耳后血管枕支为蒂,能够设计出两种SMAS岛状瓣,为耳支架的组织覆盖方法 提供多种选择.

  5. Evaluation of clinical curative effect of auricular plaster therapy in treating dysmenorrhea%耳穴贴压治疗痛经的临床疗效评价

    Institute of Scientific and Technical Information of China (English)

    刘红琼; 郭晓敏

    2014-01-01

    目的:探讨耳穴贴压法治疗原发性痛经的临床疗效。方法:将120例原发性痛经患者随机分为入耳穴贴压治疗组与口服元胡止痛对照组,观察3个月经周期治疗后痛经疼痛程度变化。结果:与口服元胡止痛片治疗相比,耳穴贴压法治疗3个月经周期后痛经疼痛程度差异有统计学意义(P<0.05)。结论:耳穴贴压法可有效缓解痛经症状,值得临床推广应用。%Objective:To observe the clinical curative effect of auricular plaster therapy in treating primary dysmenorrhea. Methods:120 cases of primary dysmenorrhea were randomly divided into the acupuncture and auricular plaster therapy group and the control group with oral analgesic.We observed the changes of dysmenorrhea pain after the treatment for 3 menstrual cycles. Results:After 3 menstrual cycles treatment,the dysmenorrhea pain between the two groups had significant differences(P<0.05). Conclusion:The auricular plaster therapy can effectively alleviate the symptoms of dysmenorrhea,so it is worthy of clinical application.

  6. Study on compound health thick soup of Tremella fuciformis and Auricularia auricular%银耳黑木耳复合保健羹的研究

    Institute of Scientific and Technical Information of China (English)

    陈峰; 江瑞荣; 曾霖霖; 陈秋颜; 杨小兵

    2012-01-01

    为了探索银耳、黑木耳深加工的新路,本文研究了银耳黑木耳复合保健羹的生产工艺。应用了正交实验设计确定复合保健羹的最佳配方,并运用了改进的模糊数学评判方法对三种不同配方保健羹进行比较。结果表明:银耳黑木耳复合保健羹的最佳配方为银耳12%,黑木耳5%,冰糖8%,柠檬酸0.05%,柠檬酸钠0.05%..海藻酸钠0.15%,黄原胶0.15%:模糊综合评判结果与正交实验结果一致。%In order to explore the new direction of processing of Tremella fuciformis and Auricularia auricular, the processing technique of compound health thick soup made from Tremella fuciformis and Auricularia auricular was studied. Orthogonal designs were applied to obtain the best prescription and fuzzy mathematics was applied to compare the three different formulations of thick soup. The results indicated Ihat the best formulation of the compound health thick soup was Tremella fuciformis 12% ,Auricularia auricular 5% ,rock candy 8% ,citrio acid 0.05%,sodium citrate 0.05%,sodium alginate 0.15%,xanthan gum 0.15%. The results of fuzzy comprehensive evaluation was consistent with orthogonal test.

  7. 针刺结合耳穴治疗失眠临床观察%A Randomized Control Study of Acupuncture Plus Auricular-plaster Therapy for Insomnia

    Institute of Scientific and Technical Information of China (English)

    赖旖; 罗敏; 邱剑锋

    2011-01-01

    Objective : To investigate the efficacy of acupuncture plus auricular-plaster therapy in treating insomnia. Methods: Twenty patients with insomnia were randomly allocated to two groups, acupuncture plus auricular-plaster ( study group )and simple medication with diazepam ( control group ). One course of treatment consisted of four weeks. The Pittsburgh Sleep Quality Index ( PSQI ) was used to assess sleep quality in both groups before and after treatment. A difference of PSQI score between pretreatment and posttreatment was compared between the groups. Results: After treatment there was a significant difference in clinical therapeutic effect between the study and control groups ( P<0.05 ) . Conclusion ; Acupuncture plus auricular-plaster therapy has a marked therapeutic effect on insomnia and is an effective therapy for treating insomnia.%目的:观察针刺结合耳穴贴压治疗失眠的临床疗效.方法:将40例失眠患者随即分为两组,针刺结合耳穴组(观察组)和单纯药物组(对照组),4周为1疗程.两组在治疗前后分别进行匹兹堡睡眠质量指数测验( PSQI),观察指数前后差值作组间比较.结果:经过治疗后,两组疗效比较,差异有统计学意义(P<0.05).结论:针刺结合耳穴治疗失眠疗效显著.

  8. Exercise and manual auricular acupuncture: a pilot assessor-blind randomised controlled trial. (The acupuncture and personalised exercise programme (APEP Trial

    Directory of Open Access Journals (Sweden)

    Hurley D

    2008-03-01

    Full Text Available Abstract Background Evidence supports the use of exercise for chronic low back pain (CLBP; however, adherence is often poor due to ongoing pain. Auricular acupuncture is a form of pain relief involving the stimulation of points on the outer ear corresponding with specific body parts. It may be a useful adjunct to exercise in managing CLBP; however, there is only limited evidence to support its use with this patient group. Methods/Design This study was designed to test the feasibility of an assessor-blind randomised controlled trial which assess the effects on clinical outcomes and exercise adherence of adding manual auricular acupuncture to a personalised and supervised exercise programme (PEP for CLBP. No sample size calculation has been carried out as this study aims to identify CLBP referral rates within the catchment area of the study site. The researchers aim to recruit four cohorts of n = 20 participants to facilitate a power analysis for a future randomised controlled trial. A computer generated random allocation sequence will be prepared centrally and used to allocate participants by cohort to one of the following interventions: 1 six weeks of PEP plus manual auricular acupuncture; 2 six weeks of PEP alone. Both groups will also complete a further six weeks of self-paced exercise with telephone follow-up support. In addition to a baseline and exit questionnaire at the beginning and end of the study, the following outcomes will be collected at baseline, and after 7, 13 and 25 weeks: pain frequency and bothersomeness, back-specific function, objective assessment and recall of physical activity, use of analgesia, perceived self-efficacy, fear avoidance beliefs, and beliefs about the consequences of back pain. Since this is a feasibility study, significance tests will not be presented, and treatment effects will be represented by point estimates and confidence intervals. For each outcome variable, analysis of covariance will be performed on

  9. Identification of the pathogen causing black skin of Auricularia auricular%黑木耳“黑皮病”病原菌鉴定

    Institute of Scientific and Technical Information of China (English)

    刘佳宁; 马银鹏; 王玉文; 张介驰; 张丕奇

    2015-01-01

    确定黑木耳“黑皮病”的病原菌。根据科赫法则,从黑龙江省和吉林省的多个黑木耳主产区采集病原菌样本,经分离纯化得到病原菌菌株,通过对菌落、分生孢子和菌丝等形态观察及鉴定确认,从黑木耳代料栽培袋中分离出的致病病原菌,其形态与可可毛色二孢菌Lasiodiplodiatheobromae最为相似。为进一步确认该病原菌的分类地位,提取其ITS序列并与该属内11个不同品种进行系统分析。将该菌的ITS序列与GenBank中已知可可毛色二孢菌Lasiodiplodia theobromae比对,其遗传距离差异为0.0000,相似度为99.999%,与形态学鉴定结果一致。在东北地区造成黑木耳“黑皮病”的病原菌为可可毛色二孢菌。%To identify the pathogen causing black skin of Auricularia auricular. According to Koch rule, Auricularia auricular pathogens samples were collected in Heilongjiang and Jilin,Pathogn strains were isolated and purified,Through the morphological observation and identification of the colonies, spores and hyphaes,it was confirmed that the morphology of pathogenicbacteria isolated from Auricularia auricular substitute cultivation bag was most similar with Lasiodiplodia theobromae.To further confirm the taxonomic status of pathogenic bacteria, its ITS sequences were extracted and systematic analysis was conducted with the 11 different species within the genus. The ITS sequencesof the bacteria was comparedwith Lasiodiplodia theobromae known in the GenBank,the genetic distance difference was 0.0000,the similarity was 99.999 %, consistent with the result of the morphological identification. In the northeast of China,the pathogen causing black skin of Auricularia auricular was Lasiodiplodia theobromae.

  10. Reconstituição experimental da parede torácica de gatos com implante heterógeno de cartilagem auricular conservada em glicerina a 98% Experimental reconstitution of the cat's thoracic wall with dog conchal cartilage implant preserved in 98% glycerin

    Directory of Open Access Journals (Sweden)

    Josaine Cristina da Silva Rappeti

    2003-12-01

    Full Text Available Com o objetivo de testar o implante de cartilagem auricular heteróloga conservada em glicerina a 98% como alternativa para reparar defeitos na parede torácica em felinos, foram estudados doze animais adultos, sendo distribuídos em dois grupos GI e GII, e avaliados após 60 dias de pós-operatório. Todos os animais foram submetidos à ressecção costal na porção média do tórax abrangendo a 7ª, 8ª e 9ª costelas e posterior implante de cartilagem conchal heteróloga conservada em glicerina a 98%. No GI, foi preservada a musculatura adjacente, já no GII, a musculatura foi retirada. Os animais foram avaliados clinicamente no pós-operatório e, ao final do período, submetidos à eutanásia e necropsia para avaliação macroscópica e microscópica da região do implante. Observou-se proliferação de tecido fibrovascular neovascularizado sobre o implante, com aderência pulmonar e diafragmática em algumas das unidades experimentais. O implante de cartilagem heteróloga conservado em glicerina a 98% pode ser utilizado para reconstrução de parede costal cujo defeito abranja o espaço de parte de três costelas. O implante em 60 dias é substituído por tecido cicatricial, sem apresentar sinais clínicos de rejeição.Twelve adult cats were divided in groups GI and GII with the objective of testing a dog auricular cartilage implant conserved in 98% glycerin as an alternative to repair thoracic wall defects. All animals were submitted to a resection of the medial portion of the thorax by removal of the 7th, 8th and 9th ribs and posterior cartilage implantation. GI had the adjacent musculature preserved and in GII cat's had it removed. The animals were clinically evaluated in the post operative period and after sixty days submitted to euthanasia for microscopic evaluation of the implanted local. Proliferation of granulation tissue and neomorph over the implant was observed in all animals and some had lung and diaphragm adherence. The

  11. Celulitis por citomegalovirus

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    A. Ruiz Lascano

    2002-12-01

    Full Text Available Las lesiones cutáneas por citomegalovirus (CMV son infrecuentes y a menudo una manifestación tardía de una enfermedad sistémica, que generalmente anuncia un curso fatal. Comunicamos un caso de celulitis por CMV: una mujer de 70 años con trasplante renal efectuado 1 mes antes de la consulta, terapia inmunosupresora con ciclosporina A y metilprednisona. La paciente ingresó por fiebre, dolor e impotencia funcional en pierna derecha. Comprobamos la existencia de una placa de 8 por 4 cm eritematoedematosa. La tratamos con antibióticos sin mejoría, por lo que realizamos un estudio histopatológico de piel que mostró cambios citopáticos compatibles con infección por CMV. Los cultivos bacteriológicos y micológicos fueron negativos. La inmunohistoquímica específica para CMV y el estudio de reacción en cadena de la polimerasa (PCR de la biopsia de piel fueron positivas, al igual que la antigenemia. El tratamiento con ganciclovir produjo la mejoría del cuadro clínico. En la literatura revisada no hemos encontrado la celulitis como manifestación de enfermedad cutánea por CMV.

  12. Synergistic Radiation Protective Effect of Purified Auricularia auricular-judae Polysaccharide (AAP IV with Grape Seed Procyanidins

    Directory of Open Access Journals (Sweden)

    Haina Bai

    2014-12-01

    Full Text Available The aim of this study was to investigate the synergistic antioxidant potential and protective effect of grape seed procyanidins (GSP in combination with Auricularia auricular-judae polysaccharides (AAP IV on radiation injury in splenocytes. Rat splenocyte irradiation resulted in significantly higher apoptosis rate, malondialdehyde (MDA (p < 0.005, reactive oxygen species (ROS (p < 0.01; cell viability, total superoxide dismutase (T-SOD (p < 0.01, catalase (CAT (p < 0.01, glutathione peroxidase (GSH-PX (p < 0.05, activity and glutathione (GSH (p < 0.01 levels were significantly reduced, compared with the control group. “GSP + AAP IV” treatment of rat splenocytes at doses of “GSP (0.3 μg/mL + AAP IV (50 μg/mL” displayed higher radioprotective and antioxidative effects than the administration of either GSP or AAP IV, as evident by lower levels of MDA (p < 0.001 concentration, as well as higher cell viability and T-SOD (p < 0.05, CAT (p < 0.005, GSH-PX (p < 0.01 and GSH content compared to the radiation group. In addition, in vivo studies have shown that “GSP + AAP IV” significantly ameliorated the decrease of spleen index (p < 0.005 and spleen GSH (p < 0.005 levels and significantly inhibited the increase of MDA (p < 0.005 levels of spleen with radiation-induced damage, compared with the non-treated group. The in vivo and in vitro results suggested that GSP and AAP IV have a synergistic protective effect against radiation-induced injury by improving the antioxidant and immunomodulation activities.

  13. STUDY ON THE THERAPEUTIC EFFECT AND MECHANISMS OF AURICULAR ACUPUNCTURE FOR TREATMENT OF EXPERIMENTAL DIABETES MELLITUS IN THE RABBIT

    Institute of Scientific and Technical Information of China (English)

    MA Ruiling; YUAN Qing; WANG Guobin

    2002-01-01

    In the present study,fasting blood glucose (FBG)concentration and serum insulin concentration and chenges of the ultramicrostructure of the pancreatic islet cells are used as the indexes to evaluate the therapeutic effect of aurioular acupuncture in the treatment of experimental diabetes mellitus(DM)and to analyze ist mechanisms in the rabbit .Thirty-two rabbits are randomly divided into control,model,acupuncture and medication groups with 8 cases being in each group.DM model is established by intravenous injection of 4% Alloxan (150mg/kg).Otopoints used are low-resistanoa points of Yidan(MA-SC 6),Neifenmi (MA-IC 3), Jiaogan(MA-AH 7), Fei (MA-IC 1), Wei (MA-IC),Shen (MA-SC),etc..Inmedication group, the animals are fed with glbenzcyclamied, ( 1.25 mg/kg/day). The treatment of both groups is given once daily, 20 sessions altogether. Results display that after 2 courses of treatment (20 sessions), in comparison with pre-treatment and model group, FBG contents in acupuncture and medication groupsd decreased significantly (P<0.01), while insulin contents of acupuncture and medication groups increaesd remarkably (P<0.05). No significant differences between acupuncture and medication groups in FBG and insulin contents. Accordingly, electron microscopic dbservation shows some improvements in partial organells as Iysosome being fewer,reduction of the nucleolar swelling, etc. in both acupucture group and medication group. It shows that restoration of the structure of islet β-cells of the pancreas, increase of the synthesis and release of insulin as well as the activity of insulin mayy contribute to the effect of auricular acupuncture in lowring blood glucose level in DM rabbits.

  14. Avaliação da acupressão auricular na síndrome do ombro doloroso: estudo de caso

    Directory of Open Access Journals (Sweden)

    Ana Paula Zanelatto

    2013-10-01

    Full Text Available A Síndrome do Ombro Doloroso (SOD é definida como dor e limitação funcional decorrente do acometimento de estruturas estáticas e dinâmicas do ombro, como ligamentos, cápsula e músculos. É uma das queixas mais comuns e incapacitantes do sistema musculoesquelético na população em geral com uma prevalência estimada entre 15 a 25%. Este estudo objetivou avaliar os resultados da acupressão auricular quando usada como terapia no tratamento da Dor crônica, secundária à SOD, quanto ao efeito analgésico e terapêutico satisfatório e o tempo estimado de tratamento. Para a obtenção do objetivo foi realizado um Estudo de Caso que teve como intervenção a acupressão auricular com esferas de cristais e como indicador de resultado o questionário Penn Shoulder Score (PSS - Brasil. Os dados foram analisados qualitativa e quantitativamente. Conclui-se que a auriculoterapia é uma importante técnica terapêutica, pois o estudo demonstrou uma melhora na pontuação total do PSS - Brasil em 34,3%.

  15. Clinical Observation on Acupuncture Plus Auricular Acupuncture in Treating Insomnia for 60 Cases%针灸配合耳针治疗失眠症60例

    Institute of Scientific and Technical Information of China (English)

    赵云; 李志轩

    2014-01-01

    目的:观察针灸配合耳针治疗失眠症的临床疗效。方法对60例失眠患者,以针刺百会、神门、内关、三阴交为主穴,配合耳针皮质下、神门、心、肾、垂前。结果经治疗后,治愈30例,显效12例,有效12例,无效6例。总有效率90%。结论针刺配合耳穴治疗失眠疗效显著。%Objective To observe the clinical effect of treating insomnia by acupuncture and auricular acupuncture .Methods 60 cases of patients with insomnia were treated by acupoint , such as BaiHui, ShenMen, NeiGuan, SanYinJiao, coordinated auricular acupuncture point such as Subcortical, ShenMen, Xin, Shen, ChuiQian.Result After treatment, 48 cases were cured, 6 cases were markedly effective, 6 cases were ineffective .The cure rate fou 80%, The total effective rate was 90%.Conclusion The effect of treating insomnia by acupuncture and ear pressure was significant .

  16. Desarrollo de modelo preoperatorio basado en el remodelado auricular anatomo-eléctrico para la predicción del éxito de la ablación quirúrgica concomitante de la fibrilación auricular crónica

    OpenAIRE

    Martin Gutiérrez, Elio

    2015-01-01

    TEMÁTICA La ablación quirúrgica de la fibrilación auricular (FA), como cualquier procedimiento invasivo, es exigible que se aplique bajo indicaciones consensuadas, con una probabilidad de éxito alta y no suponiendo un incremento significativo de la morbilidad ni de la complejidad; sobre todo si se realiza de forma concomitante a otro procedimiento quirúrgico, principal indicación de la intervención. No obstante, si se revisa la evidencia recogida en las guías clínicas1,2 y otros documento...

  17. Novos anticoagulantes orais no tromboembolismo venoso e fibrilhação auricular New oral anticoagulants in the treatment of venous thromboembolism and atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Luís Silvestre

    2012-03-01

    Full Text Available Os antagonistas da vitamina K foram, durante mais de 50 anos, os únicos anticoagulantes orais disponiveis. A imprevisibilidade da farmacocinética e farmacodinâmica desta classe de fármacos, responsável pela dificuldade na sua utilização, conduziu à necessidade do desenvolvimento de novas moléculas anticoagulantes. Estão actualmente diponíveis os resultados dos estudos de novos anticoagulantes orais no tromboembolismo venoso e na fibrilhação auricular, que se revêem neste trabalho.For more than 50 years, vitamin K antagonists were the only oral anticoagulants available. The unpredictability of its pharmacokinetics and pharmacodynamics, responsible for its difficult clinical management, has raised the need of new anticoagulants. Results of trials involving the new anticoagulants in venous thromboembolism and atrial fibrillation are now available and reviewed in this paper.

  18. Clinical Efficacy of a Modified Nagata Method That Retains the Fascia Pedicle of the Mastoid Skin Flap in Auricular Reconstruction of Chinese Microtia Patients.

    Science.gov (United States)

    Wang, Wang-Shu; Yan, Dong-Mei; Chen, Jun-Yang; Zhang, Duo; Shao, Ying; Peng, Wei-Hai

    2016-03-01

    The purpose of this study was to search for an enhanced blood supply in the distal edge of the skin at the mastoid area in total auricular reconstruction. The authors modified the Nagata method by reserving a subcutaneous fascia pedicle (diameter, 3 to 5 mm) at the intersection of the point 11 to 13 mm from the residual ear tragus (or tragus projection) and 8 to 10 mm from the lowest point of the residual ear lobe. Compared with the traditional Nagata method group, the modified Nagata method group that retained the fascia pedicle of the mastoid skin flap had higher rates of excellent and good flaps (p fascia pedicle of the mastoid skin flap, had a reduced incidence of skin flap necrosis.

  19. Osteomielitis por salmonella

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    Alicia Velázquez Pérez

    2014-08-01

    Full Text Available Se presenta el caso de una paciente femenina de color blanco y dos años de edad, con diagnóstico prenatal de sicklemia, que desde edades tempranas tiene problemas de la enfermedad. Ingresó en esta ocasión por una de las complicaciones infecciosas que ocasiona este padecimiento, una osteomielitis del húmero izquierdo, aislándose el germen en el hemocultivo realizado, una salmonella. Necesitó de tratamiento enérgico y prolongado; se obtuvo un resultado satisfactorio en la evolución de la enfermedad y se sigue sistemáticamente por consulta externa en la actualidad

  20. Dermatitis canina por Malassezia

    Directory of Open Access Journals (Sweden)

    Rejas López, Juan

    2008-05-01

    Full Text Available La dermatitis por Malassezia en perros en generalmente una complicación a procesos alérgicos, seborreicos, presencia de pliegues, etc. aunque también se han descrito otras presentaciones, como la hipersensibilidad contra esta levadura. La demostración de la presencia de Malassesia pachydermatis se hace de manera sencilla mediante citología. El tratamiento de esta dermatitis puede ser tópico u oral.

  1. Dermatitis canina por Malassezia

    OpenAIRE

    Rejas López, Juan

    2008-01-01

    La dermatitis por Malassezia en perros en generalmente una complicación a procesos alérgicos, seborreicos, presencia de pliegues, etc. aunque también se han descrito otras presentaciones, como la hipersensibilidad contra esta levadura. La demostración de la presencia de Malassesia pachydermatis se hace de manera sencilla mediante citología. El tratamiento de esta dermatitis puede ser tópico u oral.

  2. Evaluation of the efficacy of a novel radical neck dissection preserving the external jugular vein, greater auricular nerve, and deep branches of the cervical nerve

    Directory of Open Access Journals (Sweden)

    Li Y

    2013-04-01

    Full Text Available Yadong Li, Jinsong Zhang, Kai Yang Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China Background: Conventional radical neck dissection often causes a variety of complications. Although the dissection method has been improved by retaining some tissues to reduce complications, the incomplete dissection may cause recurrence of disease. In the present study, we developed a novel radical neck dissection, which preserves the external jugular vein, the greater auricular nerve, and the deep branches of the cervical nerve, to effectively reduce complications and subsequently, to promote the postoperative survival quality. Methods: A total of 100 cases of radical neck dissection were retrospectively analyzed to evaluate the efficacy, rate of complication, and postoperative dysfunction of patients treated with the novel radical neck dissection. Data analysis was performed using the Chi-square test. Results: Compared with conventional radical neck dissection, the novel radical neck dissection could significantly reduce complications and promote postoperative survival quality. Particularly, the preservation of the external jugular vein reduced the surgical risk (ie, intracranial hypertension and complications (eg, facial edema, dizziness, headache. Preservation of the deep branches of the cervical nerve and greater auricular nerve resulted in relatively ideal postoperative functions of the shoulders and ear skin sensory function (P 0.05. Conclusion: Our novel radical neck dissection procedure could effectively reduce the complications of intracranial hypertension, shoulder dysfunction, and ear sensory disturbances. It can be used as a regular surgical approach for oral carcinoma radical neck dissection. Keywords: oral cancer, head and neck cancer, squamous cell carcinoma, survival quality, neck dissection, recurrence

  3. causada por Fusarium moniliforme

    Directory of Open Access Journals (Sweden)

    Mariano Mendoza Elos

    2006-01-01

    Full Text Available El objetivo de éste trabajo fue determinar la resistencia horizontal de 134 líneas S1 de maíz al hongo Fusarium moniliforme. La enfermedad fue inducida mediante inoculación en la etapa de floración masculina bajo condiciones de campo utilizando la técnica del palillo. Las líneas se evaluaron en México en 2002. La estimación de la enfermedad se hizo en dos ocasiones con una separación de 20 días. Las evaluaciones mostraron que las líneas Roque-801, 804, 1103 y 1405 fueron resistentes en la primera evaluación. Las tasas de incremento de la enfermedad variaron de 0,01 a 0,229 por unidad por día. Las líneas mostraron bajos niveles de enfermedad de 0 a 1 % en la primera evaluación. En la segunda evaluación, los niveles de enfermedad variaron de 49 a 100 %. En un programa de mejoramiento genético estas líneas pueden ser utilizadas para mejorar la resistencia horizontal del maíz a la pudrición del tallo causada por Fusarium moniliforme

  4. Vejigas animales como sitios de oviposición y desarrollo de moscas en festividades, Heredia - Costa Rica Animal bladders as oviposition and breeding sites por flies after festivities in Heredia, Costa Rica

    Directory of Open Access Journals (Sweden)

    Olger Calderón Arguedas

    2008-12-01

    Full Text Available Se realizó un recuento del número de vejigas dispersas en 15 manzanas del centro urbano de Barva, Heredia, luego de la celebración de las mascaradas, actividad enmarcada en las fiestas patronales de la ciudad. Adicionalmente se llevó a cabo una evaluación de los huevos, larvas y adultos de mosca presentes en 2 vejigas que fueron descartadas en lugares públicos y que no fueron contaminadas con tierra, fluidos u otros detritos. Luego de la actividad se contaron 29 vejigas, las cuales estuvieron localizadas en tendido eléctrico (55,2%, aceras (27,6%, jardines (6,9%, desagües (6,9% y techos (3,4%. Los grupos de moscas observados pertenecieron a las familias Calliphoridae (Cochliomyia macellaria, Lucilia eximia, Phaenicia cuprina, Chrysomyia megacephala, Sarcophagidae (Sarcophaga sp., Muscidae (Musca domestica y Phoridae. Los promedios de huevos y larvas por vejiga fueron 176 y 44 respectivamente. Los resultados demuestran que las vejigas crudas constituyen un eficiente atrayente para diversas especies de moscas de importancia en salud pública, lo que plantea la necesidad de buscar alternativas de tratamiento para las mismas con el fin de garantizar la sostenibilidad de la tradición minimizando la contaminación del entorno urbano.A study of the number of animal bladders dispersed in 15 blocks in the urban core of Barva- Heredia was performed following the masquerades, a traditional celebration during the festivities of the city. Additionally, an evaluation of the eggs, larvae and adult flies was performed in two bladders that were discarded in public areas, which were free from soil, fluids, or other debris. In total, 29 bladders were counted. They were located on power lines (55,2%, sidewalks (27,6%, drainages (6,9% and roofs (3,4%. The flies observed corresponded to the families Calliphoridae (Cochliomyia macellaria, Lucilia eximia, Phaenicia cuprina, Chrysomyia megacephala, Sarcophagidae (Sarcophaga sp., Muscidae (Musca domestica, and

  5. Miotoxicidade por organofosforados

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    Cavaliere Maria J.

    1996-01-01

    Full Text Available Os organofosforados são um grupo de compostos químicos amplamente utilizados em agropecuária como inseticidas, ocasionando intoxicações acidentais em animais e humanos, e mesmo sendo utilizados em tentativas de suicídio. A toxicidade desses produtos decorre sobretudo de insuficiência cárdio-respiratória por compromentimento do sistema nervoso autônomo. Sabe-se que alguns destes compostos induzem em animais de experimentação e em humanos, uma miopatia caracterizada por degeneração de células musculares, comprometendo sobretudo a musculatura respiratória. Baseado no fato de que este comprometimento contribui para a piora da função respiratória, propõe-se um protocolo de avaliação rotineira de miotoxicidade por compostos organofosforados, através de uma bateria mínima e suficiente de colorações e reações histoquímicas para quantificação da necrose muscular. Utilizaram-se como modelo experimental, grupos de ratos albinos (Wistar intoxicados com o organofosforado paraoxon, com e sem antídotos (atropina ou pralidoxima. Verificou-se nos grupos tratados com paraoxon e paraoxon mais atropina, necrose de fibras musculares no diafragma, que atingia em determinadas áreas até 15% das fibras. No grupo tratado com paraoxon mais pralidoxima, a necrose foi mínima, evidenciando o papel mioprotetor deste último antídoto.

  6. Por mil devaluados pesos

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    Annie Rodríguez Collázos

    2013-03-01

    Full Text Available El estudio de lo popular y lo urbano hasta ahora se ha centrado en el comportamiento y en algunas relaciones de los habitantes con su entorno. “Por mil devaluados pesos. Publicidad popular y urbana”, pretende explorar las formas de publicidad, dispersas en diferentes espacios populares y urbanos en Bogotá, identificando esquemas y formas características de sus propios códigos comunicativos; se centran en un objeto de estudio consistente en las estrategias publicitarias y los códigos comunicativos en los mensajes publicitarios populares en las subculturas de San Victorino, 7 de Agosto y Sanandresito de San José.

  7. Comparing the content of type II collagen from different parts of costal cartilage and auricular cartilage%不同部位肋软骨与耳软骨的Ⅱ型胶原蛋白差异性比较

    Institute of Scientific and Technical Information of China (English)

    张中航; 陈振宇

    2016-01-01

    Objective To compare the content of typeⅡcollagen between the autologous 6th,7th,8th costal cartilages and auricular cartilages. Methods By using florescent real-time quantitative PCR methods to test the level of mRNA of typeIIcollagen in the autologous 6th,7th,8th costal cartilages and auricular cartilages. By using immunohistochemistry and HE staining methods to test the protein content of typeIIcollagen and the amount of chondrocytes in the 6th,7th ,8th costal cartilage and auricular cartilage.Results The type II collagen mRNA’s level in 6th,7th,8th costal cartilages were significantly higher than that in the auricular cartilage(9.3±1.2,8.9±0.5,9.7±1.3 vs. 0.8±0.6);The typeⅡcollagen’s the relative gray value in 6th,7th,8th costal cartilages were significantly higher than that in the auricular cartilage(14 545±398,15807±736,13 257±802 vs. 6 310±514;The measurement of chondrocytes in 6th,7th,8th costal cartilages were significantly more than that in the auricular cartilage. Conclusion The amount of chondrocytes and the expression of typeⅡcollagenin autologous 6th,7th,8th costal cartilages were more than auricular cartilage in patients. The autologous 6th,7th,8th costal cartilages were the best choice for auricular scaffold on ear reconstruction.%目的:比较第6、7、8肋软骨以及耳软骨的Ⅱ型胶原蛋白含量。方法利用RT-PCR检测方式测得Ⅱ型胶原蛋白mRNA在第6、7、8肋软骨和耳软骨中的表达。利用免疫组化以及HE染色方法检测第6、7、8肋软骨和耳软骨中Ⅱ型胶原蛋白和软骨细胞的含量。结果Ⅱ型胶原蛋白mRNA在第6、7、8肋软骨的表达明显高于耳软骨(9.3±1.2、8.9±0.5、9.7±1.3 vs.0.8±0.6);第6、7、8肋软骨的Ⅱ型胶原蛋白相对灰度值明显高于耳软骨(14545±398、15807±736、13257±802 vs.6310±514);第6、7、8肋软骨测量的软骨细胞数目明显多于患者耳软骨。结论自体第6、7、8肋软骨Ⅱ型胶原蛋白

  8. Aspectos clínicos e macroscópicos da palatoplastia imediata com implante de cartilagem da pina articular, conservada em glicerina a 98%, após indução experimental de fenda palatina em cães Clinic and macroscopic view of immediate palatoplasty with auricular pinna cartilage preserved in 98% glycerin in canine experimental palat cleft

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    Emerson Antônio Contesini

    2003-02-01

    Full Text Available Os defeitos de espessura completa do palato que resultam em comunicação oro-nasal raramente cicatrizam espontaneamente. Eles requerem reparo cirúrgico, porém, pode ser difícil obter cicatrização satisfatória devido às condições próprias das cavidades nasal e oral. Neste experimento, foram utilizados 14 cães, reunidos em dois grupos de igual número. Todos animais foram submetidos à indução de fenda palatina experimental. O grupo G1 foi o controle, cuja palatoplastia foi realizada a partir da confecção de "flap" muco-periósteo. No grupo G2, foi utilizada cartilagem da pina auricular conservada em glicerina a 98% entre o osso palatino e o muco-periósteo. Os animais foram avaliados macroscopicamente quanto ao processo cicatricial, por radiografias para a regeneração óssea e por rinoscopia para observar a regeneração da mucosa nasal. Foi observada a cicatrização da mucosa oral a partir do 10º dia, com deiscência de sutura em dois animais do grupo G1. A radiografia demonstrou evolução na cicatrização óssea, num processo mais acelerado no grupo G2 quando comparado ao grupo G1. A rinoscopia revelou, aos 60 dias, completa regeneração da mucosa nasal em ambos os grupos. Ao final do período de avaliação foi observada macroscopicamente, completa fusão óssea nos animais do grupo G2 e incompleta nos do grupo G1, o que demonstrou a interferência benéfica do implante no processo cicatricial do grupo G2.The incomplete defects of hard palate result in oro-nasal fistula seldom cure themselves in a spontaneous way, due to limited condition in oral and nasal cavity it may be difficult to obtain satisfactory cicatrization, requiring surgery to interfere in the healing process. Fourteen dogs arranged in two groups were submitted to experimental hard palate cleft. The G1 group was the control group, in which palatoplasty was achieved with mucous-periosteum flap. In the G2 group, a preserved at 98% glycerin auricular pinna

  9. Forty-nine cases of insomnia treated by acupoint catgut-embedding therapy in combination with auricular point sticking%穴位埋线配合耳穴贴压治疗失眠49例

    Institute of Scientific and Technical Information of China (English)

    郝玉林; WANG Fang

    2011-01-01

    @@ Insomnia is defined as difficulty in falling into sleep and failure to acquire normal sleep, resulting in short sleep time, even staying asleep the whole night in serious case, which impacts on the normal daytime activity and brings the deep pains to the patients.The author had treated 49 cases of insomnia with acupoint catgut-embedding therapy in combination with auricular point sticking from February 2008 to August 2009.The report is as follows.

  10. 针刺配合按摩耳穴治疗贝尔面瘫研究述评%Research Review on Acupuncture Combined with Massaging Auricular Points for the Treatment of Bell’s Palsy

    Institute of Scientific and Technical Information of China (English)

    蒋霞; 李应昆

    2012-01-01

    Objective:To discuss the clinical values of acupuncture combined with massaging auricular points for the treatment of Bell's palsy. Methods;The modern clinical treatment methods for Bell's palsy as well as their advantages and disadvantages were analyzed through the analysis of relevant literature. Results: Acupuncture with massaging auricular points for the treatment of Bell's palsy has high security,less pain and simplicity in operation,which is easy to be accepted by patients. Conclusion:Acupuncture, combined with massaging auricular points has good therapeutic effect in treating Bell's palsy.%目的:探讨针刺配合按摩耳穴治疗贝尔面瘫的临床价值.方法:通过收集、整理、分析相关文献,探讨现代临床治疗贝尔面瘴的治疗方法及其优缺点.结果:针刺配合按摩耳穴治疗贝尔面瘴安全性高,痛苦小,操作简便,患者易于接受.结论:针刺配合按摩耳穴治疗贝尔面瘫疗效较好.

  11. The Auricular Beans on the Recovery of Gastrointestinal Function after Abdominal Surgery%耳穴埋豆对外科术后胃肠功能腹胀恢复的探讨

    Institute of Scientific and Technical Information of China (English)

    张兆莉

    2014-01-01

    目的:观察耳穴埋豆对术后胃肠功能腹胀恢复的效果。方法:将80例患者分为对照组和试验组,对照组给予常规护理,试验组在常规护理基础上采用耳穴埋豆治疗。结果:试验组的腹胀发生率低于对照组,肠蠕动恢复及肛门排气时间均早于对照组。结论:耳穴埋豆法能有效降低腹胀的发生率。%Objective:To observe the effect of auricular beans on the recovery of gastrointestinal function in postoperative abdominal distension. Method:80 patients were divided into control group and experimental group.The control group was given routine nursing,the experimental group was given auricular beans on the basis of conventional care buried treatment.Result:In the experimental group,the incidence of abdominal distension was lower than the control group,the intestinal peristalsis and anus exhaust time were earlier than that of the control group.Conclusion:Auricular bean method can effectively reduce the incidence of abdominal distension.

  12. Ojo por ojo

    OpenAIRE

    Ramón del Llano Ibáñez

    2011-01-01

    Nuestro pan y café de la mañana se acompaña de noticias alrededor de ejecuciones, de fosas clandestinas, de batallas del ejército, de balaceras en las calles y civiles caídos por balas perdidas : la muerte acompaña nuestro desayuno. Las calaveras de azúcar del día de muertos hoy son calaveras reales y amargas : 40 000 muertos en cuatro años después que el Presidente Calderón declaró la guerra a los narcotraficantes. Se han apresado a varios e importantes miembros de los cárteles : pero han si...

  13. Sepsis por shigella flexneri

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    César Cabrera C

    2005-04-01

    Full Text Available Se presenta un caso raro de sepsis por Shigella flexneri en una paciente de 45 años de edad quien estando hospitalizada para el estudio de un tumor cerebral, requirió el uso de manitol y dosis altas de corticoides; luego de ello presenta deposiciones líquidas con moco y sangre, desarrolla síndrome de respuesta inflamatoria sistémica, luego se aísla Shigella flexneri en el hemocultivo; recibió tratamiento antibiótico con ciprofloxacina. Se describen las características del caso y se comenta de acuerdo con la revisión de literatura.

  14. Onicomicosis por hongos fuliginosos

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    Ingrid Salas-Campos

    2009-12-01

    Full Text Available Justificación y objetivo: Las infecciones de las uñas producidas por hongos son un problema de frecuente consulta dermatológica. Los dermatofitos son la mayor causa de estas infecciones, siendo Trichophyton rubrum el agente etiológico más importante. Sin embargo, los hongos no dermatofitos, tanto hialinos como fuliginosos, pueden ser también responsables de estos cuadros clínicos. Debido a que estos hongos tienden a ser resistentes a los antimicóticos comúnmente usados para tratar las onicomicosis, es que se hace indispensable que el clínico se asegure por medio de un examen de laboratorio de la etiología de la infección. Métodos: Se estudiaron tres casos de pacientes con lesiones en uñas, que acudieron al laboratorio de Micología Médica, Facultad de Microbiología, Universidad de Costa Rica. Se realizaron los análisis de rutina para aislamiento e identificación de hongos patógenos. Resultados: En los tres casos estudiados se observó al examen directo micelio fuliginoso. En uno de los casos se aisló e identificó Scytalidium dimidiatum, hongo que presenta resistencia a los antifúngicos utilizados para tratar onicomicosis. Conclusión. El reporte de hongos diferentes a los dermatofitos como agentes etiológicos de onicomicosis es importante para que el médico pueda elegir el tratamiento más recomendado para este tipo de infección.

  15. Motivado por cirujanos

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    Carlos Salazar-Vargas

    2010-12-01

    Full Text Available Comenzaba la década de los 60 y nuestro grupo nerviosamente iniciaba lecciones en los hospitales de San José. En aquellos años, el estudiante de medicina empezaba su contacto con pacientes, por lo menos 1 ó 2 años después de iniciada la carrera. El estudio del ser humano normal que ya habíamos concluido, continuaba con el del enfermo, y más adelante aprenderíamos el tratamiento. La enfermedad descrita en el libro, de pronto se convertía en un enfermo, y es a este quien hoy veíamos, cohibido pero inquisidor, en la cama de un hospital. Los profesores nos enseñaban a interrogar y a examinar a los pacientes, y cada gesto suyo, cada pregunta, cada maniobra, eran celosamente guardados en la memoria de los educandos. Con claridad percibíamos, aun a temprana edad, las diferencias entre los especialistas, y casi de manera involuntaria, cada quien iba tomando partido y escogía su futuro camino. Fue durante esos tempranos años, cuando mi vida se cruzó con la de 7 maravillosas personas y excelentes cirujanos, que marcaron para siempre mi destino y, sin quererlo ellos, me hicieron inclinarme por la cirugía. Dos eran serios y profundamente académicos: el Dr. Manuel Aguilar Bonilla y el Dr. Vesalio Guzmán Calleja; 3, decididos, incansables y muy hábiles: el Dr. Longino Soto Pacheco, el Dr. Claudio Orlich Carranza y el Dr. Carlos Prada Díaz, y 2, abordables, prácticos, joviales y amistosos: el Dr. Fernando Valverde Soley y el Dr. Randall Ferris Iglesias….

  16. AURICULAR ACUPUNCTURE FOR BURNING MOUTH SYNDROME%耳针治疗灼口综合征的效果观察

    Institute of Scientific and Technical Information of China (English)

    孙艳楠; 吴迎涛; 王万春

    2011-01-01

    目的 了解耳针治疗灼口综合征的效果.方法 灼口综合征病人80例,随机分为2组,实验组42例,采用耳针电刺激+耳压治疗;对照组38例,口服维生素B2、维生素E和谷维素治疗,30 d为1个疗程.疗程结束后,实验组停止电刺激,继续耳压治疗;对照组按原剂量口服药物.两组分别于治疗前、治疗1个疗程、治疗后3个月进行疼痛程度评定,并进行比较.结果 对照组治疗后3个月疼痛程度较治疗前及治疗1个疗程降低,差异有显著性(F=36.368,q=6.807、4.641,P<0.01);实验组治疗1个疗程、治疗后3个月疼痛程度均较治疗前降低,差异有显著性(F=24.191,q=3.808、8.513,P<0.01).实验组治疗1个疗程及3个月后疼痛程度较对照组降低,差异有显著性(t=18.000、17.902,P<0.05).结论 耳针治疗灼口综合征病人有效.%Objective To observe the efficacy of auricular acupuncture for burning mouth syndrome (BMS).Methods This study was carried out in 80 patients with BMS, who were randomized to experimental group (42 cases) and control group (38 cases).Patients in the experimental group were treated with combination of electric auricular acupuncture and ear pressing; those in treatment the control group with oral vitamin B2, vitamin E and oryzanolum, the time of therapy was 30 for both groups.After completion of the course, the electric stimulation was discontinued, while ear pressing continued in experiment group; to those in the control, the treatment was the same as previously.The degree of pain was evaluated and compared, in both groups, before and after one course and three months of treatment.Results After three months of treatment, the pain in the control group reduced compared with pre-therapy and after one treatment course, the differences were significant (F=36.368; q=6.807,4.641; P<0.01); after one course and three months of treatment, the pain in experimental group was lightened versus pre-therapy (F=24.191;q=3.808,8.513;P

  17. A modified approach to remain major auricular nerve and parotid fascia in parotidectomy%腮腺筋膜和耳大神经保留的改良方法

    Institute of Scientific and Technical Information of China (English)

    李明月; 张伟; 刘宁; 陈方文

    2009-01-01

    目的:介绍一种腮腺切除术中保留耳大神经和腮腺筋膜的改良方法.方法:取常规S形切口,在腮腺筋膜浅面先向前游离皮瓣至腮腺近前缘,再于耳垂前1cm处纵形切开腮腺筋膜,在腮腺筋膜深面、腮腺组织表面向后游离至胸锁乳突肌,形成皮肤筋膜瓣.在游离过程中,将耳大神经主干及耳垂支、耳后支保留在皮肤筋膜瓣上,最后向前游离筋膜瓣.完成腮腺切除后,将前、后腮腺筋膜瓣折叠,拉紧缝合.结果:45/46例患者获得随访.术后3例分别在5个月、9个月和11个月出现轻度Frey综合征.9例术后出现耳垂暂时麻木,1~3个月后恢复感觉.下颌后凹陷不明显,无涎瘘发生.结论:改良的手术方法能完好地保留腮腺筋膜和耳大神经耳垂支、耳后支,显著降低相应并发症的发生.%PURPOSE: To introduce a new method of remaining major auricular nerve and parotid fascia in parotideetomy. METHODS: Traditional S-shaped incision was used, the skin flap was separated to the anterior border of the parotid gland on the superfieial of parotid fascia, then the deep parotid fascia was cut longitudinal in front of the auricular lobule. After that, the skin flap was separated backward to the stem cleidomastoid museles. The major auricular nerve and its two branches were kept in the skin flap. Finally, the fascia flap was freed forward, the two sides of the parotid fascia were drawn tight and sutured together. RESULTS: 45 out of 46 patients were followed up, 3 of them developed Frey's syndrome, and 11 months after surgery, respectively; 9 patients had temporary auricular lobule numb and recovered 1 to 3 months later. No salivary fistula was noted. CONCLUSIONS: The new approach can remain parotid fascia and major auricular nerve branches completely with minor complications.

  18. Análisis de coste-utilidad del manejo de la fibrilación auricular concomitante en España Cost-utility analysis of concomitant atrial fibrillation management in Spain

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    María Jesús López Gude

    2010-01-01

    Full Text Available Objetivos: La fibrilación auricular (FA es la arritmia más común en la práctica clínica; es un factor de riesgo de accidente cerebrovascular (ACV, y está asociada a una importante morbilidad y mortalidad. Nuestro objetivo fue realizar un análisis de coste-utilidad de las diferentes opciones de tratamiento en pacientes >40 años con FA concomitante con valvulopatía mitral en España, desde la perspectiva del Sistema Nacional de Salud. Métodos: Se realizó una evaluación económica mediante un modelo de Markov con cuatro estados de salud (ritmo sinusal, FA, ACV dependiente, muerte simulando una cohorte de 1.000 pacientes en cada opción de tratamiento más cirugía de válvula mitral (tratamiento farmacológico, ablación quirúrgica y ablación por catéter. El horizonte temporal fue de 5 años, con ciclos de 3 meses. Los datos de costes y efectos se obtuvieron de la revisión de la literatura y de la opinión de expertos clínicos, descontados al 3,5% anual. Se realizó un análisis de sensibilidad probabilístico para determinar la robustez de nuestros resultados. Resultados: Los años de vida ajustados por calidad (AVAC ganados fueron 3,29, 3,89 y 3,83, respectivamente, para las alternativas de no ablación, ablación quirúrgica y ablación por catéter. Los costes por paciente fueron de 5.770€, 10.034€ y 11.289€, respectivamente. La razón coste/AVAC de ablación quirúrgica frente a no ablación fue de 7.145€. La ablación quirúrgica resultó dominante frente a la ablación por catéter. El análisis probabilístico de sensibilidad mostró que los resultados del modelo fueron robustos. Conclusiones: La ablación quirúrgica es una opción de tratamiento coste-efectiva en los pacientes con FA concomitante, con una razón coste-efectividad por debajo del umbral de eficiencia comúnmente aceptado en España.Objectives: Atrial fibrillation (AF is the most common arrhythmia in clinical practice; this disorder is a risk factor

  19. Sociedad por Acciones Simplificada

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    Carlos Andrés Arcila Salazar

    2009-06-01

    Full Text Available En Colombia, aspectos como la responsabilidad limitada; supresión de la llamada doctrina de ultra vires; duración ilimitada; eliminación de la regla, una acción, un voto; remedios al abuso de los derechos; posibilidad de eliminar prohibiciones a los administradores, libertad de establecer restricciones para la transferencia de acciones y la simplificación de los procedimientos de fusión; son inviables bajo nuestra legislación. Sin embargo, la Ley 1258 de 2008, ha incorporado al derecho societario colombiano un nuevo tipo societario híbrido, llamado “Sociedad por Acciones Simplificada”. Esta forma societaria híbrida se basa en un principio básico: garantizar amplia libertad a los empresarios en la estructuración de sus relaciones a través de disposiciones contractuales. La S.A.S. provee a los empresarios significativa flexibilidad contractual, a la vez que preserva beneficios como la limitación de la responsabilidad.

  20. Sociedad por Acciones Simplificada

    Directory of Open Access Journals (Sweden)

    Carlos Andrés Arcila Salazar

    2009-07-01

    Full Text Available En Colombia, aspectos como la responsabilidad limitada; supresión de la llamada doctrina de ultra vires; duración ilimitada; eliminación de la regla, una acción, un voto; remedios al abuso de los derechos; posibilidad de eliminar prohibiciones a los administradores, libertad de establecer restricciones para la transferencia de acciones y la simplificación de los procedimientos de fusión; son inviables bajo nuestra legislación. Sin embargo, la Ley 1258 de 2008, ha incorporado al derecho societario colombiano un nuevo tipo societario híbrido, llamado “Sociedad por Acciones Simplificada”. Esta forma societaria híbrida se basa en un principio básico: garantizar amplia libertad a los empresarios en la estructuración de sus relaciones a través de disposiciones contractuales. La S.A.S. provee a los empresarios significativa flexibilidad contractual, a la vez que preserva beneficios como la limitación de la responsabilidad.

  1. Sino-European transcontinental basic and clinical high-tech acupuncture studies-part 1: auricular acupuncture increases heart rate variability in anesthetized rats.

    Science.gov (United States)

    Gao, Xin-Yan; Liu, Kun; Zhu, Bing; Litscher, Gerhard

    2012-01-01

    Evidence-based research concerning the effects of high-tech acupuncture on autonomic function was performed by two research teams from China and Austria. This study describes the first transcontinental teleacupuncture measurements in animals. Heart rate (HR) and heart rate variability (HRV) recordings in 10 male Sprague-Dawley anesthetized rats were performed under stable conditions in Beijing, China, and the data analysis was completed in Graz, Austria. The electrocardiograms (ECGs) were recorded by an HRV Medilog AR12 system during acupuncture of the ear and body (PC6 Neiguan, CV12 Zhongwan, ST36 Zusanli). The data were analyzed using specially adapted novel Austrian software. HR did not change significantly during any acupuncture stimulation in anesthetized rats (ear acupuncture, PC6, CV12, or ST36). Total HRV only changed significantly (P = 0.025) during auricular acupuncture (acupoint heart). The low-frequency/high-frequency ratio parameter decreased significantly (P = 0.03) during stimulation of ST36. This change was based on intensification of the related mechanism of blood pressure regulation that has been demonstrated in previous studies in humans. Modernization of acupuncture research performed as a collaboration between China and Austria has also been demonstrated.

  2. Sino-European Transcontinental Basic and Clinical High-Tech Acupuncture Studies—Part 1: Auricular Acupuncture Increases Heart Rate Variability in Anesthetized Rats

    Directory of Open Access Journals (Sweden)

    Xin-Yan Gao

    2012-01-01

    Full Text Available Evidence-based research concerning the effects of high-tech acupuncture on autonomic function was performed by two research teams from China and Austria. This study describes the first transcontinental teleacupuncture measurements in animals. Heart rate (HR and heart rate variability (HRV recordings in 10 male Sprague-Dawley anesthetized rats were performed under stable conditions in Beijing, China, and the data analysis was completed in Graz, Austria. The electrocardiograms (ECGs were recorded by an HRV Medilog AR12 system during acupuncture of the ear and body (PC6 Neiguan, CV12 Zhongwan, ST36 Zusanli. The data were analyzed using specially adapted novel Austrian software. HR did not change significantly during any acupuncture stimulation in anesthetized rats (ear acupuncture, PC6, CV12, or ST36. Total HRV only changed significantly (P=0.025 during auricular acupuncture (acupoint heart. The low-frequency/high-frequency ratio parameter decreased significantly (P=0.03 during stimulation of ST36. This change was based on intensification of the related mechanism of blood pressure regulation that has been demonstrated in previous studies in humans. Modernization of acupuncture research performed as a collaboration between China and Austria has also been demonstrated.

  3. UTILIZAÇÃ O DE EQUIPAMENTOS DE PROTEÇÃ O INDIVIDUAL POR FRENTISTAS DE POSTOS DE COMBUSTÍVEIS: CONTRIBUIÇÃ O DA ENFERMAGEM

    Directory of Open Access Journals (Sweden)

    Laurelize Pereira Rocha

    2014-01-01

    Full Text Available Se objetivó identificar la utilización de equipamientos de protección individual, por asistentes/ empleados de gasolineras de la ciudad de Rio Grande-RS. Se trata de un estudio cuantitativo, exploratorio, descriptivo, realizado con 221 trabajadores de 22 estaciones de servicio, por medio de cuestionario y registro de observación no participante y sistemático. Para análisis fueron realizadas estadística descriptiva y el control de calidad de las preguntas, se deo por medio del test Alpha de Cronbach, obteniendos el resultado de 0,96. Se verificó la predominancia de la multifunción y la utilización de botas, delantal, guantes, máscara, lentes, protector auricular y uniforme, conforme autoreferido. La observación confirmó únicamente el uso de botas y uniformes, constatandose inconsistencia. Los puntos planteados demuestran la necesidad de actuación de las enfermeras, a través de acciones de protección y prevención de los riesgos y peligros para la salud del trabajador, estimulando la vigilancia de la salud.

  4. Por que sou rondoniano

    Directory of Open Access Journals (Sweden)

    Mércio Pereira Gomes

    2009-01-01

    Full Text Available Numa revisão contextualizada no tempo e projetada pelos seus resultados, a obra do sertanista marechal Cândido Rondon (1867-1958 é avaliada positivamente pela dedicação à causa dos povos indígenas do Brasil, pela formação de uma ética de respeito do brasileiro para com os índios e pela institucionalização do dever do Estado brasileiro de proteger, assistir e ajudar os povos indígenas a manterem-se coesos e autônomos e ao mesmo tempo se projetarem no mundo mais amplo. A vida de Rondon é acompanhada desde a sua formação como cadete da Escola Militar, como membro da Igreja do Apostolado Positivista, como comandante da Expedição Rondon (1907-1930, que levou o telégrafo de Cuiabá a Porto Velho, e especialmente como criador e dirigente-mor do Serviço de Proteção aos Índios (SPI, 1910-1967. Rondon é o criador da expressão "Morrer se preciso for, matar nunca", que pautou a ação de indigenistas brasileiros que fizeram os primeiros contatos com muitos povos indígenas desde 1910. E muitos morreram seguindo essa norma, numa clara demonstração do novo espírito humanista criado pela atitude rondoniana. O indigenismo brasileiro implantado por Rondon teve altos e baixos ao longo de quase cem anos, que hoje prossegue pela Fundação Nacional do Índio (Funai. De fato, muitos povos indígenas perderam suas terras e muitos foram dizimados no século XX, mas os mais de 220 que sobreviveram vêm crescendo em número, obtendo suas terras (13% do território nacional e conquistando novos espaços político-culturais no Brasil.This paper reviews the life and work of Brazilian Indianist Marshall Cândido Rondon. Rondon's life is marked by a profound dedication to the Brazilian Indian cause and to instilling in Brazilians a respect for Indian peoples. He influenced the Brazilian government in shaping a policy of protecting, assisting, and helping Indian peoples retain cohesive, self-determined societies. He also encouraged Indians to

  5. 疏肝健脾饮结合耳穴贴压治疗肠易激综合征52例%Treating 52 cases of irritable bowel syndrome with Shugan Jianpi Yin plus auricular pressure

    Institute of Scientific and Technical Information of China (English)

    陈宇基

    2015-01-01

    目的:探讨我院脾胃科经验方疏肝健脾饮结合耳穴贴压治疗肠易激综合征(IBS)的疗效。方法:将肠易激综合征患者104例随机分为两组,治疗组给予经验方疏肝健脾饮结合耳穴贴压法治疗;对照组给予匹维溴胺治疗,各52例,观察两组治疗前后症状的变化。结果:中药结合耳压贴压治疗的总有效率为94.87%,匹维溴胺的总有效率为77.78%(P<0.05)。结论:疏肝健脾饮结合耳穴贴压治疗肠易激综合征疗效确切,疗程短,值得临床推广。%Objective: To discuss efficacy of Shugan Jianpi Yin plus auricular pressure on IBS. Methods: 104 cases were randomly divided into two groups, 52 cases in each group. The treatment group was treated with Shugan Jianpi Yin plus auricular pressure; the control group was treated with pinaverium bromide. Results: The total efficiency was 94.87% in the treatment group, higher than 77.78% in the control group (P<0.05). Conclusion: Treating IBS by Shugan Jianpi Yin plus auricular pressure can receive a good effect, is worthy of promotion.

  6. Clinical Study of Auricular Plaster Therapy for Post-laparoscopic Cholecystectomy Nausea and Vomiting%耳穴压豆缓解腹腔镜胆囊切除术后恶心、呕吐的临床研究

    Institute of Scientific and Technical Information of China (English)

    费华华; 贾丽萍

    2015-01-01

    目的:观察耳穴压豆缓解腹腔镜胆囊切除术后恶心、呕吐的效果。方法将240例腹腔镜胆囊切除术患者随机分为治疗组和对照组,每组120例。两组均采用常规护理,治疗组在此基础上给予耳穴压豆治疗。观察两组恶心、呕吐发生情况。结果治疗组恶心、呕吐发生率为46.7%,对照组为60.8%,两组比较差异具有统计学意义(P<0.05)。结论耳穴压豆法能缓解腹腔镜胆囊切除术后患者恶心、呕吐症状。%Objective To investigate the efficacy of auricular plaster therapy for post-laparoscopic cholecystectomy nausea and vomiting. Methods Two hundred and forty laparoscopic cholecystectomy patients were randomly allocated to treatment and control groups, 120 cases each. Both groups received routine nursing care. In addition, the treatment group received auricular plaster therapy. The incidence of nausea and vomiting was observed in the two groups.Results The incidence of nausea and vomiting was 46.7% in the treatment group and 60.8% in the control group; there was a statistically significant difference between the two groups (P<0.05).Conclusion Auricular plaster therapy can relieve postoperative nausea and vomiting in laparoscopic cholecystectomy patients.

  7. 耳穴贴压对甲状腺手术患者应激反应的影响%Effects of auricular therapy on stress reaction in patients with thyroidoperation

    Institute of Scientific and Technical Information of China (English)

    彭素珍

    2014-01-01

    目的:探讨耳穴贴压对甲状腺手术患者焦虑及血压、心率有无影响。方法:选取甲状腺手术患者50例,随机分为观察组与对照组各25例,对照组给予常规护理,观察组在常规护理基础上给予耳穴贴压,比较两组患者术晨血压、心率变化及术后焦虑水平有无差异。结果:观察组患者焦虑水平低于对照组,血压、心率变化幅度小,差异均具有统计学意义。结论:耳穴贴压可降低患者焦虑水平,减少血压、心率的变化,利于甲状腺手术的顺利进行,值得在临床推广。%Objective:To study the effect of auricular pressure on the patients anxiety, blood pressure, heart rate who undergoing thyroid operation. Methods:Select 50 cases of patients with thyroid operation, randomly divided into observation group and control group with 25 cases in each group, the control group was given routine nursing, the observation group given auricular pressure on the basis of conventional care. Results: the observation group blood pressure, heart rate and anxiety is lower, P<0.05. Conclusion:Auricular can decrease anxiety level of patients, reduce blood pressure, and change of heart rate, which is good for thyroid operation and worth the clinical promotion.

  8. 耳穴贴压结合心理护理对患者失眠状态的影响%The Effect of Auricular Application Pressure Combined with Psychological Care on the Insomnia State of Patients with Insomnia

    Institute of Scientific and Technical Information of China (English)

    陈秀娟

    2015-01-01

    Objective: To observe the effect of auricular application pressure combined with psychological nursing on the insomnia state of pa-tients with insomnia.Methods:172 cases of insomnia were randomly divided into the treatment group and the control group , 86 cases in each group.The treatment group was treated with auricular application pressure and psychological care and the control group was given estazolam or neu-roleptic treatment and conventional care, with the clinical efficacy compared between the two groups 2 months after the treatment.Results:The to-tal effective rate in the treatment group was 97.67% and that in the control group was 74.42 %, with a significant difference between the two group ( P <0.05).Conclusion: Auricular application pressure combined with psychological nursing can bring about an curative effect on patients with insomnia.%目的:观察耳穴贴压结合心理护理治疗患者失眠的临床疗效。方法:选择失眠患者172例,随机分为治疗组和对照组,每组86例,治疗组予耳穴贴压治疗和心理护理;对照组予艾司唑仑或安定治疗和常规护理;治疗2个月后,比较两组患者的临床疗效。结果:治疗组总有效率为97.67%,对照组总有效率为74.42%,两组比较差异有统计学意义( P <0.05)。结论:耳穴贴压结合心理护理对患者失眠有效。

  9. Hemorragias intracraneales de carácter evitable asociadas a anticoagulantes orales en pacientes con fibrilación auricular Avoidable intracranial hemorrhages associated with oral anticoagulants in patients with atrial fibrillation

    OpenAIRE

    A. García Luque; J. Torello Iserte; J.R. Castillo Ferrando

    2011-01-01

    Introducción y objetivo: El aumento de la prescripción de anticoagulantes orales ha provocado un aumento de hemorragias intracraneales, la reacción adversa más grave asociada a este grupo farmacológico. El objetivo del estudio es evaluar el carácter evitable de hemorragias intracraneales asociada a anticoagulantes orales que causan ingreso hospitalario en pacientes con fibrilación auricular. Método: Supervisión de las historias clínicas de los pacientes que ingresaron en los Hospitales Univer...

  10. Culture and identification of the chondrocytes from auricular cartilage of rhesus monkey%猕猴耳廓软骨细胞的体外培养与鉴定

    Institute of Scientific and Technical Information of China (English)

    张金宁; 王旭东; 杨驰

    2001-01-01

    Objective:To culture the auricular chondrocytes of rhesus monkeyin vitro,and to certify the possibility of auricular cartilage as an ideal donor site for chondrocytes transplantation.Methods:The auricular cartilages of 6 rhesus monkeys were dissected and digested,the chondrocytes were isolated and cultured in F-12 medium.The changes of cellular morphology were investigated with inverted microscope.The cellular activities were studied with immunohistochemistry(IHC).Results:The homogenous,high-activity chondrocytes were harvested and cultured iv vitro successfully and IHC showed that there was no significant difference between type Ⅰ and type Ⅱ collagen stain in 3rd generation.Conclusions:Auricular cartilage of rhesus monkey is an ideal donor site for chondrocytes transplantation.%目的 掌握猕猴耳廓软骨细胞的体外分离、培养和鉴定技术,探讨耳廓软骨作为软骨细胞供区的可行性。材料与方法:对6只猕猴进行耳廓软骨取材、软骨细胞的分离,并行单层贴壁培养。通过倒置显微镜观察细胞生长情况并行细胞生长曲线的绘制;通过免疫组织化学染色对细胞分泌的基质成分进行鉴定。结果:6只猕猴的耳廓软骨经分离后,获得了高纯度、高活性的软骨细胞,并成功地进行了体外培养;软骨细胞倍增时间为98小时;免疫组织化学染色发现体外培养的软骨细胞具有分泌胶原基质的能力,但第三代细胞分泌Ⅰ、Ⅱ型胶原的能力无明显区别。结论:利用猕猴耳廓软骨细胞体外分离及培养,能成功地获得具有体内活性的软骨细胞,耳廓软骨是一种易获取的软骨细胞供区。

  11. Treating one case of intractable insomnia by acupuncture, bloodletting in auricular point plus sharp-eared%针刺、耳穴配合耳尖放血治愈顽固性失眠1例

    Institute of Scientific and Technical Information of China (English)

    王燕; 陈华德

    2012-01-01

      With the accelerating pace of biochemical, various pressure is unexpected. The Insomnia becomes a common clinical disease. Acupuncture, bloodletting in auricular point plus sharp-eared is effective in treating insomnia.%  随着生化节奏的不断加快,各种压力突如其来,失眠成为临床常见疾病。运用针刺、耳穴配合耳尖放血治疗失眠取得良好地疗效。

  12. Registro Nacional de Internación por Insuficiencia Cardíaca

    Directory of Open Access Journals (Sweden)

    Raúl Borracci

    2009-01-01

    Full Text Available IntroducciónLa insuficiencia cardíaca representa una de las principales causas de internación con una tasa elevada de complicaciones y cuyo enfoque no parece que haya mejorado en los últimos años.ObjetivosConocer el perfil epidemiológico y clínico, analizar las medidas terapéuticas y la evolución durante la internación y a los 3 meses de pacientes admitidos por insuficiencia cardíaca descompensada.Material y métodosRegistro prospectivo, multicéntrico de pacientes internados por insuficiencia cardíaca descompensada en 31 centros de todo el país que aceptaron la invitación a participar del registro. Se analizaron variables vinculadas con la presentación y la evolución hospitalaria y a los 90 días.ResultadosSe incluyeron 736 pacientes, mediana de edad 74 años (64-82, 41% mujeres, 75% hipertensos, 27% diabéticos, 20% infarto previo, 30% fibrilación auricular crónica, 17% insuficiencia renal crónica, 18% EPOC. Sólo el 29% era de etiología isquémico-necrótica. El 47% había tenido internación en el último año por insuficiencia cardíaca. Las causas de descompensación más frecuentes fueron infecciones, suspensión del tratamiento y transgresión alimentaria.Las formas graves de presentación (shock cardiogénico, edema agudo de pulmón, anasarca representaron el 30%. El 60% de los pacientes se internaron en área crítica. La mediana de permanencia fue de 7 (5-11 días. La mortalidad hospitalaria fue del 8%. A los 90 días, la reinternación fue del 24,5% y la mortalidad posalta fue del 12,8%.ConclusionesEl presente registro confirma que se trata de una población de edad avanzada con una incidencia alta de comorbilidades. Muchas descompensaciones ocurren por factores prevenibles. La tasa de complicaciones es elevada y no se redujo en la última década.REV ARGENT CARDIOL 2009;77:33-39.

  13. Porøse materialer

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2000-01-01

    Dette undervisningsnotat er en samling af noter, der refererer til den indledende del af kurset Materialmekanik og Porøse materailer på Insitut for Bærende Konstruktiner og Materialer (BKM).......Dette undervisningsnotat er en samling af noter, der refererer til den indledende del af kurset Materialmekanik og Porøse materailer på Insitut for Bærende Konstruktiner og Materialer (BKM)....

  14. Transcutaneous auricular vagus nerve stimulation regulates expression of growth differentiation factor 11 and activin-like kinase 5 in cerebral ischemia/reperfusion rats.

    Science.gov (United States)

    Ma, Jingxi; Zhang, Lina; He, Guoqian; Tan, Xiaodan; Jin, Xinhao; Li, Changqing

    2016-10-15

    Growth differentiation factor 11 (GDF11), as a rejuvenation factor in heterochronic parabiosis, can increase proliferation of primary brain capillary endothelial cells (ECs). However, the angiogenic role of GDF11 in ischemia-induced brain injury is still unclear. There are no previous reports on the spatiotemporal expression of GDF11 in cerebral ischemia/reperfusion (I/R) rats. Our recent work has strongly suggested that transcutaneous auricular vagus nerve stimulation (ta-VNS) reduces infarct size and induces angiogenesis in focal cerebral I/R rats. This study focused on expression of GDF11 and activin-like kinase 5 (ALK5) and the effects of ta-VNS in a rat cerebral I/R model. For ta-VNS, electrical stimulation of the left cavum concha (1h duration) using percutaneous needles was initiated 30min after induction of ischemia. Expression of GDF11 was analyzed by enzyme-linked immunosorbent assay, immunohistochemistry, real-time polymerase chain reaction, and western blot 24h, 3d, and 7d after reperfusion. In addition, neurobehavioral function, EC proliferation, and expression of ALK5 in ECs in the peri-infarct cortex were measured. Results showed that levels of GDF11 were significantly elevated after cerebral I/R, both in plasma and the peri-infarct cerebral cortex. Interestingly, splenic GDF11 levels decreased after ischemia. ALK5 was expressed in ECs in the peri-infarct cerebral cortex where active vessel remodeling was noted. ta-VNS improved neurobehavioral recovery, upregulated cerebral GDF11 and downregulated splenic GDF11, indicating a brain-spleen communication during stroke. ta-VNS also increased expression of ALK5 in ECs and stimulated proliferation of ECs. These results suggest that, after cerebral ischemia, GDF11 redistributes and participates in angiogenesis as an angiogenic factor that acts at least in part through ALK5. GDF11/ALK5 may represent a new potential therapy target for stroke. PMID:27653860

  15. Transplante de cartilagem costal autóloga no reparo de desvio do pavilhão auricular de cães: estudo experimental Autologus costicartilage graft to repair external ear deviation of dogs: an experimental study

    Directory of Open Access Journals (Sweden)

    Duvaldo Eurides

    1996-04-01

    Full Text Available Neste experimento, 12 cães com idade entre 7 e 12 meses foram submetidos a técnica cirúrgica com objetivo de apresentar novo método para reparo de desvio lateral da orelha externa, mediante transplante autólogo de cartilagem costal. Verificou-se que as orelhas apresentaram postura ereta, movimentos aparentemente normais e ausência de desvio. Macroscopicamente o enxerto encontrava-se firmemente aderido a cartilagem auricular e a pele. Pela microscopia óptica observou-se em torno da cartilagem costal presença de tecido conjuntivo fibroso. A técnica cirúrgica avaliada poderá ser utilizada para correção de desvio lateral da orelha de cães.To perform the research twelve dogs between 7 and 12 months old were submitted to a surgical technique in order to test new method to repair lateral external ear deviation with an autologus costicartilage implant. The ears presented erect posture, normal appearance, movement and no deviations. Macroscopic examination showed that the implant was firmly attached to the auricular cartilage and skin. Around the costicartilage fibrous connective tissue was observed by optical microscopy. This surgical technique can be used to correct lateral deviations of dogs ears.

  16. Evaluation of the Immediate Effect of Auricular Acupuncture on Pain and Electromyographic Activity of the Upper Trapezius Muscle in Patients with Nonspecific Neck Pain: A Randomized, Single-Blinded, Sham-Controlled, Crossover Study

    Directory of Open Access Journals (Sweden)

    Andréia Cristina de Oliveira Silva

    2015-01-01

    Full Text Available Background. The aim of the present study was to assess the immediate effects of auricular acupuncture (AA on the electromyographic (EMG activity of the upper trapezius muscle and pain in nonspecific neck pain (NS-NP patients. Twelve patients with NS-NP (NS-NP group and 12 healthy subjects (HS Group were enrolled in a randomized, single-blinded, crossover study. Each subject received a single session of AA and sham AA (SAA. Surface EMG activity was measured in the upper trapezius muscle at different “step contractions” of isometric shoulder elevation (15%, 20%, 25%, and 30% MVC. The outcome measure in patients with NS-NP was based on the numerical pain rating scale (NRS. AA treatment led to a significant decrease in EMG activity in both groups (NS-NP group: p = 0.0001; HS group: p < 0.0001—ANOVA test. This was not the case for the SAA treatment (NS-NP group: p = 0.71; HS group: p < 0.54. Significant decreases (p < 0.001 in the NRS were found for both treatments (AA and SAA. This study demonstrated the immediate effect of auricular acupuncture on the electromyographic activity of the upper trapezius muscle but the effect of this intervention on pain symptoms in patients with nonspecific neck pain was inconclusive.

  17. Debating some issues on the national standard Standardized Manipulation of Acupuncture and Moxibustion,Part 3:Auricular Acupuncture%国家标准《针灸技术操作规范第3部分:耳针》的若干问题研讨

    Institute of Scientific and Technical Information of China (English)

    李桂兰; 郭义; 陈泽林; 李桂华

    2009-01-01

    从耳针操作规范化研究编制的意义、科学性及关键问题三方面对国家标准编制中的主要难点与争议问题进行探讨,主要包括:怎样规范耳针操作;标准制定的依据与科学性;术语和定义的选择;为何仅规范4种耳针的操作方法等.进一步提出了需要研究和完善的问题.%The main difficulties and disputable problems on develping the national standard Standardized Manipulation of Acupuncture and Moxibustion, Part 3: Auricular Acupuncture are debated in this paper from the three aspects of its meaning, scientific basis and key point. The difficult points mainly include manipulation standandization of auricular acupuncture, basis and science of the standards stipulated, selection of technical terms and definition, and why only the four kinds of manipulations are used for auricular acupuncture. Finally, the authors suggest that the Standardized Manipulation of Acupuncture and Moxibustion , Part 3: Auricular Acupuncture needs further to be studied and improved.

  18. Auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap%耳后延迟皮瓣自体肋软骨支架法外耳再造术

    Institute of Scientific and Technical Information of China (English)

    李高峰; 谭军; 罗滔; 丁卫; 欧阳华伟; 刘婉丽

    2014-01-01

    目的 探讨耳后延迟皮瓣自体肋软骨支架法外耳再造术的临床效果.方法 手术分3期进行:Ⅰ期为耳后皮瓣延迟术,术后3周左右进行Ⅱ期手术;Ⅱ期为自体肋软骨支架再造、延迟皮瓣覆盖及自体中厚皮片移植外耳再造术,术后半年据情进行Ⅲ期手术;Ⅲ期行耳屏再造、耳甲腔加深和再造耳局部修整术等.结果 对先天性小耳畸形28例,31只耳,分次完成Ⅰ~Ⅲ期手术23只耳,余8只耳只完成Ⅰ、Ⅱ期手术.术后外耳位置、大小及形态良好,并发症少,患者及家属基本满意.结论 应用皮瓣延迟术不但可获取足够面积富有血运保障的菲薄皮瓣,而且方法简单、安全,所需时间短.耳后延迟皮瓣自体肋软骨支架法外耳再造术,是一种良好的外耳再造术方法.%Objective To summarize and explore the clinical effect of auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap.Methods The procedure involved three stages.The first stage was the delay procedure of postauricular skin flap.The second stage was the auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap about 3 weeks after the delay procedure.The third stage involved construction of tragus and conchal cavity and other local correction 6 months or longer after the second stage surgery.The clinical effect,patients' satisfaction and complication were observed.Results This method was used in 28 patients,31 ears of congenital microtia.23 cases completed auricular reconstruction with three stages,the other 8 cases completed only two stages.All auricular reconstruction were successful.The location,size and shape of reconstructive ears were good.The complications were few.The patients or their relatives were basically satisfactory.Conclusions Auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap is a safe and effective method.

  19. Se los por se lo

    OpenAIRE

    José Luis Rivarola

    1985-01-01

    El sistema de la conjugación "objetiva" plantea interesantesproblemas que fueron tratados en parte por K. Heger (1966) en suestudio comparativo del francés y del español. De la comparaciónse desprende, por ejemplo, que en español hay un cierto número deambigüedades que no permiten establecer un "paradigma tan completo y unívoco" como en el caso del francés. Dentro de estas ambigüedades se encuentran las que propicia el gramema se: "El morfema [gramema] se funciona no sólo como pronombre refle...

  20. Ptose palpebral causada por Paquidermoperiostose

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    Patricia Regina de Pinho Tavares

    2014-08-01

    Full Text Available A paquidermoperiostose é uma síndrome caracterizada por acometimento cutâneo e ósseo, e em alguns casos ocorre comprometimento palpebral leve. É uma síndrome rara, idiopática ou hereditária, com provável herança autossômica dominante de penetrância variável. Descreve-se o caso de um paciente com ptose grave por paquidermoperiostose elucidando sua fisiopatologia e conduta cirúrgica aplicada.

  1. Ocorrência de úlcera por pressão em pacientes submetidos a cirurgias eletivas Ocurrencia de úlcera por presión en pacientes sometidos a cirugías electivas Occurrence of pressure ulcers in patients undergoing elective surgeries

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    Elizabeth Silva Ursi

    2012-01-01

    Full Text Available OBJETIVO: Identificar a ocorrência de úlcera por pressão em pacientes submetidos a cirurgias eletivas de porte II, III e IV. MÉTODOS: Estudo de abordagem quantitativa, com delineamento de pesquisa não experimental, tipo descritivo e prospectivo. A amostra foi composta por 148 pacientes adultos, de ambos os gêneros, submetidos à cirurgia eletiva, conforme os critérios de seleção determinados previamente. RESULTADOS: Da amostra avaliada, 108 pacientes receberam alta hospitalar, três faleceram e 37 desenvolveram úlceras por pressão. Esses pacientes apresentaram 44 lesões, sendo a maioria diagnosticada de estágio II (56,8%, seguida por lesões de estágio I (40,9% e estágio III (2,3%. As áreas corporais mais acometidas foram a região sacro/glútea (68,2%, calcâneos (18,1%, região dorsal (9% e o pavilhão auricular (4,6%. CONCLUSÃO: A ocorrência de úlcera por pressão foi de 25% indicando a necessidade de implementação de intervenções efetivas para a prevenção desse evento adverso no perioperatório.OBJETIVO: Identificar la ocurrencia de úlcera por presión en pacientes sometidos a cirugías electivas de porte II, III y IV. MÉTODOS: Estudio de abordaje cuantitativo, con delineamiento de investigación no experimental, tipo descriptivo y prospectivo. La muestra estuvo compuesta por 148 pacientes adultos, de ambos géneros, sometidos a la cirugía electiva, conforme los criterios de selección determinados previamente. RESULTADOS: De la muestra evaluada, 108 pacientes recibieron alta hospitalaria, tres fallecieron y 37 desarrollaron úlceras por presión. Esos pacientes presentaron 44 lesiones, siendo la mayoría diagnosticada de estadío II (56,8%, seguida por lesiones de estadío I (40,9% y estadío III (2,3%. Las áreas corporales más afectadas fueron la región sacro/glútea (68,2%, calcáneos (18,1%, región dorsal (9% y el pabellón auricular (4,6%. CONCLUSIÓN: La ocurrencia de úlcera por presión fue del 25

  2. CARACTERIZACIÓN CLÍNICA Y PRONÓSTICA DE LA FIBRILACIÓN AURICULAR POR VÍA ACCESORIA / Clinical and prognostic characterization of atrial fibrillation due to an accessory pathway

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    Raimundo Carmona Puerta

    2009-09-01

    Full Text Available Introduction and objectives: Atrial fibrillation is the most common arrhythmia in adults, with a prevalence of 0.4 percent in the general population. It is the main cause of embolic events and serious hemodynamic alterations, having important clinical, social and economic repercussions. Besides, it is the second most frequent arrhythmia in patients with an accessory pathway. The objective of the study is to characterise atrial fibrillation with anterograde conduction through an accessory pathway. Method: A descriptive, prospective and longitudinal study was carried out in 26 patients who were treated at the Cardiac Electrophysiology Services of the Ernesto Che Guevara Cardiology Hospital in Santa Clara during a year period. The variables related to the prevalence of atrial fibrillation, risk factors, circumstances of appearance, therapeutic options and predictors of sudden death, were studied. Results: It was determined a prevalence 34.2 percent with a predominance of the male gender. The most important risk factor was the existence of previous events of atrial fibrillation in 35 percent of the patients, which appeared most frequently during rest periods. There was a predominance of the left pathways (54 % and 84 percent of the patients required medication to achieve an acute reversion. Conclusions: Pre-excited atrial fibrillation presents an important prevalence in our environment. There was a predominance of the male gender and the left pathways. The mean RR interval during the pre-excitation was 213 milliseconds and there were minimal RR intervals of less than 170 milliseconds.

  3. Ecology and epidemiology of Screwworm, Cochliomyia hominivorax (Coquerel, 1858

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    Elkin G. Forero Becerra

    2007-12-01

    Full Text Available Screwworm myiasis causes staining fur around infested wounds with malodorous blooding exudates. Pathological effects include mechanical irritation because of larval feeding until dead of hosts under successive infestations. In natural conditions, population densities of screwworm fly are low. Its distribution follows running waters, potential hosts proximity and vegetation density. Warm and moist climate increases of screwworm populations. Among domestic animals, cattle are mostly affected by screwworm myiasis. Risk factors in animals are related to management practices. In humans, the children and the elderly, homeless and dirty, are more vulnerable. Technical aspects for analysis in planning ecological and epidemiological studies in Colombia are pointed out.

  4. Celulitis por citomegalovirus Cytomegalovirus cellulitis

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    A. Ruiz Lascano

    2002-12-01

    Full Text Available Las lesiones cutáneas por citomegalovirus (CMV son infrecuentes y a menudo una manifestación tardía de una enfermedad sistémica, que generalmente anuncia un curso fatal. Comunicamos un caso de celulitis por CMV: una mujer de 70 años con trasplante renal efectuado 1 mes antes de la consulta, terapia inmunosupresora con ciclosporina A y metilprednisona. La paciente ingresó por fiebre, dolor e impotencia funcional en pierna derecha. Comprobamos la existencia de una placa de 8 por 4 cm eritematoedematosa. La tratamos con antibióticos sin mejoría, por lo que realizamos un estudio histopatológico de piel que mostró cambios citopáticos compatibles con infección por CMV. Los cultivos bacteriológicos y micológicos fueron negativos. La inmunohistoquímica específica para CMV y el estudio de reacción en cadena de la polimerasa (PCR de la biopsia de piel fueron positivas, al igual que la antigenemia. El tratamiento con ganciclovir produjo la mejoría del cuadro clínico. En la literatura revisada no hemos encontrado la celulitis como manifestación de enfermedad cutánea por CMV.Cutaneous lesions in CMV infection are rare, often a late manifestation of systemic infection, and usually herald a fatal course. A 70 year-old woman received a kidney transplantation one month before consulting and immunosuppressive therapy that included cyclosporine A and methylprednisone. She complained of fever, local pain in her right leg, and an erythematous and swelling plaque. She was treated with intravenous antibiotics without improvement. A skin biopsy was performed and the tissue obtained was sent for bacterial and fungal cultures as well as for histological examination. Cultures were negative. The biopsy showed CMV cytopathic changes. Immunoperoxidase staining was positive for CMV and polymerase chain reaction (PCR testing revealed CMV DNA. She was treated with ganciclovir with resolution of the lesion. CMV cellulitis is a rare cutaneous manifestation

  5. 探讨耳穴贴压联合足浴对肝火扰心型失眠患者5-HT、DA含量的影响及护理%Study the Effects and Nursing of Auricular-plaster United with Foot Bath to Liver Fire Harassing of Insomnia of Patient’s Content of 5-HT and DA

    Institute of Scientific and Technical Information of China (English)

    安雪梅; 高红

    2016-01-01

    Objective To study the effects of auricular-plaster united with foot bath on 5-HT and DA content of patient with insomnia of liver ifre harassing the heart type. Methods 90 cases patients in our hospital were selected and randomly divided into auricular-plaster groups, foot bath group and bath joint group, 30 cases in each group, after treatment by different methods, 5-HT and DA content of the serum were determined before and after therapy. Results The effect of auricular-plaster united with foot bath was superior to only auricular pressure or foot bath on liver fire harassing of insomnia (P<0.05). Conclusion Auricular-plaster united with foot bath has a signiifcant effect to patient with insomnia of liver ifre harassing.%目的:研究耳穴贴压联合足浴对肝火扰心型失眠患者血浆5-羟色胺(5-HT)、多巴胺(DA)含量的影响。方法选取我院收治肝火扰心型失眠患者90例,随机分成耳穴贴压组、足浴组和联合组,每组30例,分别给予不同的治疗方式,检测治疗前、后血清中5-HT和DA的含量变化。结果耳穴贴压联合足浴疗法对肝火扰心型失眠症的疗效明显优于单纯耳穴贴压和单纯足浴疗法(P<0.05)。结论耳穴贴压联合足浴疗法对肝火扰心型失眠患者疗效十分显著。

  6. (phoenicopterus roseus por intoxicación aguda por plomo

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    D Romero

    2007-01-01

    Full Text Available La presencia de plomo en el medio ambiente es un hecho indiscutible. Ello es objeto de gran interés sanitario pues repercute tanto en la salud de los animales como en la del ser humano. El plumbismo es una intoxicación que puede afectar a cualquier especie animal. En el ámbito de la fauna silvestre se asocia principalmente a la actividad cinegética en los humedales y a la ingestión de plomo metálico por parte de las aves que frecuentan estos ecosistemas. En España cada año mueren decenas de miles de aves acuáticas como consecuencia de la ingesta de perdigones de plomo. En los individuos capturados enfermos se pueden observar signos clínicos, mientras que a partir de muestras de cadáveres se obtienen datos sobre niveles tisulares de plomo. Sin embargo la evaluación de lesiones anatomopatológicas en animales de vida silvestre es difícil de realizar por la dificultad de encontrar animales recién muertos o afectados de un cuadro agudo mortal. La reproducción de esta patología en animales de experimentación se suele realizar en cisnes, palomas o patos, pero no en flamencos, por lo que no es usual disponer de datos histológicos en esta especie. En este trabajo presentamos la clínica, analítica y estudio microscópico de diferentes tejidos de un flamenco común (Phoenicopterus roseus muerto por plumbismo.

  7. Descenso de los niveles de propéptido natriurético de tipo B-N terminal luego de la reversión de pacientes con fibrilación auricular y función ventricular conservada

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    Claudio Higa

    2011-04-01

    Full Text Available El objetivo fue comparar los niveles de Pro Péptido Natriurético tipo B-N terminal (Pro-BNP-NT basales y post reversión en pacientes con fibrilación auricular solitaria (FAS de comienzo reciente y con función ventricular izquierda conservada. Se determinaron niveles del Pro BNP NT antes y después de su reversión en treinta pacientes con FAS de comienzo reciente y fracción de eyección de ventrículo izquierdo ≥ 50%. Basalmente, los niveles de Pro BNP NT fueron significativamente más elevados respecto a un grupo control sano: 529 pg/ml (157-1763 versus 31.5 pg/ml (24-76, p < 0.0001. Las concentraciones de Pro BNP NT descendieron significativamente luego de la cardioversión de 529 (157-1763 a 318 (98-870 pg/ml, p < 0.001. Los descensos se objetivaron tanto luego de la cardioversión eléctrica como de la obtenida por vía farmacológica, 345 (153-1151 pg/ml a 169 (86-407 pg/ml, p: 0.02 y de 1624 (541-4010 pg/ml a 856 (532-1160 pg/ml, p < 0.001, respectivamente. Este fenómeno se observó fundamentalmente en aquellos con una FAS con duración mayor a 8 horas: 1289 (338-2103 a 410 (169-905 pg/ml, p < 0.001. No se observó correlación entre los cambios de la frecuencia cardíaca y del Pro BNP NT pre y post cardioversión a ritmo sinusal. Se observaron descensos significativos de Pro BNP NT basalmente y post reversión (tanto farmacológica como eléctrica en pacientes con FA de reciente aparición y función ventricular conservada. Estos descensos fueron más ostensibles a partir de las 8 horas de duración de la arritmia.

  8. Se los por se lo

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    José Luis Rivarola

    1985-12-01

    Full Text Available El sistema de la conjugación "objetiva" plantea interesantesproblemas que fueron tratados en parte por K. Heger (1966 en suestudio comparativo del francés y del español. De la comparaciónse desprende, por ejemplo, que en español hay un cierto número deambigüedades que no permiten establecer un "paradigma tan completo y unívoco" como en el caso del francés. Dentro de estas ambigüedades se encuentran las que propicia el gramema se: "El morfema [gramema] se funciona no sólo como pronombre reflexivo, sinotambién como variante combinatoria del pronombre personal complemento indirecto de la tercera persona.

  9. por el Tribunal Constitucional chileno

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    Marisol Peña Torres

    2008-01-01

    Full Text Available La modificación introducida por la reforma constitucional de agosto de 1989 al artículo 5º de la Constitución chilena sentó un criterio decisivo en la incorporación del derecho internacional de los derechos humanos al ordenamiento jurídico interno. El artículo examina la jurisprudencia del Tribunal Constitucional antes y después de esa reforma distinguiendo entre la aplicación del Derecho Internacional de los Derechos Humanos por haberse invocado en la acción deducida y la aplicación de principios y criterios hermenéuticos extraídos del mismo.

  10. 止痛方配合耳穴贴压对痛经患者的疗效观察%Clinical efficacy of analgesic prescription combined with auricular plaster therapy for dysmenorrhea

    Institute of Scientific and Technical Information of China (English)

    韩冬梅; 廉印玲

    2016-01-01

    目的 观察止痛方配合耳穴贴压治疗痛经的效果.方法 收集本院门诊收治的痛经患者60例,分为治疗组和对照组,每组30例.治疗组采用止痛方(当归、熟地、赤芍、川芎、元胡、川楝子、蒲黄、五灵脂、乌药、川牛膝、小茴香、香附、枳壳、半夏、乳香)配合耳穴贴压疗法;对照组单用止痛方,比较两组的疗效.结果 治疗组总有效率93.3%,对照组总有效率73.3%,治疗组显著优于对照组(P<0.05).结论 痛方配合耳穴贴压治疗痛经的效果优于单用止痛方.%Objective To observe the efficacy of analgesic prescription combined with auricular plaster therapy in the treatment of dysmenorrhea.Methods Sixty dysmenorrhea patients treated in our hospital clinics from May 2013 to November 2011 were randomly divided into a treatment group and a control group,30 patients in each group.The treatment group adopted the analgesic prescription (Angelica sinensis,prepared Rehmannia glutinosa,Radix Paeoniae Rubra,Ligusticum chuanxiong,Corydalis yanhusuo,Melia toosendan,Pollen Typhae,feces of Trogopterus xanthipes,Lindera aggregata,Cyathula officinalis,Foeniculum vulgare,Cyperus rotundus,Citrus aurantium,and Pinellia ternate and frankincense) combined with auricular plaster therapy,and the control group was treated with the analgesic prescription alone.The curative effects of 2 groups were compared.Results The total effectiveness of the treatment group was 93.3%,and the total effectiveness of the control group was 73.3%.The treatment group was better than the control group,and there was statistically significant difference (P < 0.05).Conclusion The analgesic prescription combined with auricular plaster therapy has better clinical efficacy than the analgesic prescription alone for the treatment of dysmenorrhea.

  11. The Treatment of External Humeral Epicondylitis by Auricular Plaster Therapy Combined with Body Acupuncture%耳穴贴压结合体针治疗肱骨外上髁炎

    Institute of Scientific and Technical Information of China (English)

    秦宏; 夏秋芳; 东贵荣

    2011-01-01

    Objective;To observe therapeutic effect of auricular plaster therapy combined with body acupuncture on external humeral epicondylitis. Methods: Eighty cases were randomly divided into observation group ( n = 40) and control group (n =40). The observation group was treated with auricular plaster therapy combined with body acupuncture, and the control group was treated with body acupuncture to observe the curative effect of the two groups. Results .-The two groups have a significant difference in MEPS mark after treatment (P 0.05). Conclusion: The curative effect of external humeral epicondylitis by auricular plaster therapy combined with body acupuncture is much better than by body acupuncture , especially in acute phase.%目的:观察耳穴贴压结合体针治疗肱骨外上髁炎的疗效。方法:将80例肱骨外上髁炎的患者随机分为试验组和对照组各40例,试验组采用耳穴贴压结合体针治疗,对照组单纯采用体针治疗,观察两组治疗前后疗效。结果:两组患者的MEPS评分与治疗前相比均有显著性差异(P<0.01)。观察组优良率40.0%,对照组优良率15.0%,两组优良率比较差异均有显著意义(P<0.01),观察组疗效优于对照组。急性期患者中观察组优良率37.5%,对照组优良率15.0%,两组优良率比较差异有统计学意义(P<0.05)。而观慢性期患者中观察组优良率2.5%,对照组优良率0%,两者比较无差异(P>0.05)。结论:采用耳穴贴压结合体针治疗肱骨外上髁炎疗效优于单纯采用体针治疗,且急性期疗效优于慢性期。

  12. Effect of auricular acupuncture on visceral pain induced by colorectal distension in rats%耳针对结直肠扩张导致大鼠内脏痛的影响

    Institute of Scientific and Technical Information of China (English)

    胡莎莎; 李晗; 王茵萍

    2013-01-01

    目的 研究耳针对结直肠扩张(CRD)所造成大鼠内脏痛的影响.方法 29只SD大鼠随机分为空白对照组(A组,7只)、模型组(B组,7只)、耳针组(C组,8只)和假针刺组(D组,7只).连续记录大鼠CRD前后、干预期及干预后各30 min的肌电图(EMG)和心率变异性(HRV),采用荧光定量PCR观察结肠中5-羟色胺1A(5-HTIA)受体mRNA的表达.结果 CRD后,B、C、D组EMG均较A组显著升高(P<0.05),但HRV与扩张前比较无统计学差异(P>0.05).C组EMG和5-HT1A受体mRNA表达较B组、D组明显降低(P<0.05).结论 耳针可有效改善CRD导致的大鼠内脏痛.这种调节作用可能与5-HT递质受体系统有关.%Objective To investigate the effect of auricular acupuncture on the visceral pain induced by colorectal distension(CRD) in rats.Methods Twenty-nine SD rats were randomly divided into four groups of A (blank control,7 rats),B (CRD model,7 rats),C (intervened with auricular acupuncture,8 rats) and D(sham acupuncture,7 rats).The electromyography(EMG) and heart rate variability(HRV) were continuously recorded each for 30 min before and after CRD and during and after intervention.The mRNA expression of 5-hydroxytryptamine1A (5-HT1A) receptor in the colon tissues was detected by fluorescent quantitative PCR.Results After CRD,EMG in groups of B,C and D was significantly higher than that in group A(P<0.05),but HRV was not markedly changed,compared with baseline (P>0.05).The mRNA expression of 5-HT1A receptor and EMG in group C were lower than those in groups of B and D (P<0.05).Conclusion Auricular acupuncture can effectively improve visceral pain induced by CRD in rats,which may be related to 5-HT receptor system.

  13. Clinical Observation on Vascular Headache Treated by Auricular Point Sticking Therapy%耳穴贴压治疗血管神经性头痛临床观察

    Institute of Scientific and Technical Information of China (English)

    郑赛林; 李福娟; 洪珏

    2011-01-01

    目的:观察耳穴贴压治疗血管神经性头痛的临床疗效.方法:将50 例符合血管神经性头痛诊断的患者随机分为两组,每组25 例.治疗组予耳穴贴压磁珠治疗,对照组予口服盐酸氟桂利嗪治疗,两组病例均以30 d 为1 个疗程,治疗1 个疗程后观察疗效.结果:治疗组总有效率为92.0%, 对照组总有效率为60.0%, 组间差异有统计学意义(P<0.01).治疗组治疗后血压下降明显(P<0.05);大脑中动脉(Middle Cerebral Artery,MCA) 、大脑前动脉(Anterior Cerebral Artery,ACA)平均流速变化明显 (P<0.01) .结论:耳穴贴压治疗血管神经性头痛疗效明显,同时具有降血压,改善大脑血流的作用.%Objective: To evaluate the clinical effect of auricular sticking therapy in treating vascular headache. Methods: Fifty patients with vascular headache were randomized into two groups, 25 cases in each. The treatment group received auricular sticking therapy with magnetic pearls, and the control group was treated by Flunarizine Hydrochloride, 30 d as a treatment session, and the results were measured after one treatment session. Result: The total effective rate was 92.0% in the treatment group while 60.0% in the control group, and the difference was significant (P<0.01). A marked decrease of blood pressure was detected in the treatment group (P<0.05). The mean velocity in middle cerebral artery and anterior cerebral artery both changed significantly (P<0.01). Conclusion: Auricular sticking therapy can significantly improve the condition of vascular headache, as well as reduce blood pressure and help cerebral blood flow.

  14. 203例房颤患者中医辨证相关因素分析%Analysis on Relative Factors of Syndrome Differentiation in 203 Patients with Auricular Fibrillation

    Institute of Scientific and Technical Information of China (English)

    汪云翔

    2012-01-01

    目的:探求心房颤动中医分型与年龄、性别及相关疾病的关系.方法:选择203例房颤患者,按中医辨证分为瘀阻心脉、痰浊闭阻、水饮凌心、心血不足、阴虚火旺、心阳不振6型,比较不同性别、年龄以及有冠心病病史、风湿性心脏病病史、高血压病病史患者各中医证型的构成情况.结果:房颤病人以老年人居多,证型以瘀阻心脉、痰浊闭阻居多.有冠心病病史的房颤患者多为瘀阻心脉、痰浊闭阻型;有高血压性心脏病的患者辨证多为瘀阻心脉、阴虚火旺;风心病引起的房颤辨证多为水饮凌心、心血不足.结论:房颤患者的中医证型与其年龄及相关病史有关,临床辨证需考虑相关因素.%Objective: To find out the relationships between TCM pattern and aging, gender and associated diseases. Method: All 203 patients were divided into six groups according to TCM syndrome differentiation, which included: blood stasis obstructing the heart, phlegm turbidity obstruction, water intimidating the heart, heart blood deficiency, Yin deficiency and fire hyperactivity, devitalization of heart Yang. The syndromes of patients with the history of coronary heart disease, rheumatic heart disease and hypertension as well as their gender and ages were analyzed. Result: Most of the patients with auricular fibrillation are the elderly and their syndromes mostly are blood stasis obstructing the heart and phlegm turbidity obstruction; the patients with the history of coronary heart disease are also of blood stasis obstructing the heart and phlegm turbidity obstruction; the patients with the history of hypertensive heart disease are differentiated as blood stasis obstructing the heart and Yin deficiency and fire hyperactivity; auricular fibrillation induced by rheumatic heart disease is mostly differentiated as water intimidating the heart and heart blood deficiency. Conclusion: TCM syndrome of auricular fibrillation is associated to

  15. Sepsis neonatal por Estreptococos Pyogenes

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    Gilberto Rodríguez-Herrera

    2009-09-01

    Full Text Available Se presenta el caso de un paciente masculino, recién nacido a término adecuado para la edad gestacional, quien nace por parto vaginal, con el antecedente de fiebre en la madre durante el periodo de postparto inmediato. Los padres consultan a los 2 días de vida pues le notan dificultad respiratoria, hipoactividad y rechazo a la leche materna. El paciente se interna y se aborda como una sepsis. Durante su estancia en el servicio de neonatología del Hospital Nacional de Niños asocia fallo respiratorio que amerita ventilación mecánica asistida por varios días en diferentes ocasiones, derrame pleural exudativo, convulsiones de origen hipóxico isquémico. Con reporte de hemocultivos positivos por Estreptococos pyogenes. El Estreptococos pyogenes o estreptococo β-hemolνtico del grupo A, fue un problema en los comienzos del siglo pasado, siendo frecuente en las infecciones puerperales y del reciιn nacido. En la actualidad es un germen sumamente raro en los procesos de sepsis neonatal.2 La gravedad de la enfermedad causada por este microorganismo en el periodo neonatal varνa desde una onfalitis crónica de bajo grado a una septicemia, una meningitis fulminante y la muerte.1 El presente artículo pretende hacer un resumen del paciente, con su evolución clínica, radiológica y además ejemplificar todas las complicaciones que tuvimos con este germen tan poco frecuente en la actualidad en sepsis neonatal.

  16. Desajuste educativo por regiones en Colombia: ¿competencia por salarios o por puestos de trabajo?

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    Castillo Caicedo Maribel

    2007-08-01

    Full Text Available Este trabajo aporta una perspectiva del fenómeno de la sobreeducación,
    entendida como un desajuste por exceso, entre el nivel educativo alcanzado
    por el individuo y el exigido por el puesto de trabajo en el cual se
    desempeña; esto se debe a que existe una demanda laboral estrecha de
    puestos de trabajo para personas calificadas en Colombia. Se analizan las
    contribuciones empíricas existentes y el debate sobre las mismas; se
    examinan las teorías que permiten explicar la existencia de un desajuste
    educativo y se realiza una revisión de la literatura internacional y
    nacional sobre el tema. Adicionalmente, se plantean una serie de hipótesis
    para desarrollar un esquema que permita determinar el comportamiento
    del individuo en el fenómeno de la sobreeducación.

  17. Ear abnormalities in patients with oculo-auriculo-vertebral spectrum (Goldenhar syndrome Anormalidades auriculares em pacientes com espectro óculo-aurículo-vertebral (síndrome de Goldenhar

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    Rafael Fabiano Machado Rosa

    2011-08-01

    Full Text Available Oculo-auriculo-vertebral spectrum (OAVS is a rare condition characterized by the involvement of the first branchial arches. PURPOSE: To investigate the ear abnormalities of a sample of patients with OAVS. MATERIALS AND METHODS: The sample consisted of 12 patients with OAVS seen at the Clinical Genetics Unit, UFCSPA/CHSCPA. The study included only patients who underwent mastoid computed tomography and with normal karyotype. We performed a review of its clinical features, giving emphasis to the ear findings. RESULTS: Nine patients were male, the ages ranged from 1 day to 17 years. Ear abnormalities were observed in all patients and involved the external (n=12, middle (n=10 and inner ear (n=3. Microtia was the most frequent finding (n=12. The most common abnormalities of the middle ear were: opacification (n=2, displacement (n=2 and malformation of the ossicular chain. Agenesis of the internal auditory canal (n=2 was the most frequent alteration of the inner ear. CONCLUSIONS: Ear abnormalities are variable in patients with OAVS and often there is no correlation between findings in the external, middle and inner ear. The evaluation of these structures is important in the management of individuals with OAVSO espectro óculo-aurículo-vertebral (EOAV é uma condição rara caracterizada pelo envolvimento dos primeiros arcos branquiais. OBJETIVOS: Verificar as alterações auriculares de uma amostra de pacientes com EOAV. MATERIAL E MÉTODOS: A amostra foi constituída de 12 pacientes com EOAV atendidos no Serviço de Genética Clínica da UFCSPA/CHSCPA. Foram incluídos no estudo apenas pacientes submetidos à tomografia computadorizada de mastoide e com cariótipo normal. Realizou-se uma revisão dos seus achados clínicos, dando-se ênfase aos achados auriculares. RESULTADOS: Nove pacientes eram do sexo masculino, idades variaram de 1 dia a 17 anos. Anormalidades auriculares foram observadas em todos os pacientes e envolveram a orelha externa (n=12

  18. 二维和三维超声技术在耳郭支架材料选择中的应用%Application of 2-dimensional and 3-dimensional ultrasound techniques in material choice of auricular framework

    Institute of Scientific and Technical Information of China (English)

    白晓珺; 胡兵; 杨松林

    2011-01-01

    Objective To observe application of 2-dimensional ( 2D ) and 3-dimensional ( 3D ) ultrasound techniques in material choice of auricular framework from autologous costal cartilages. Methods Ten male and female youths aged from 20 to 29 were selected, 2D ultrasound imaging was performed firstly on the 6 to 10 costal cartilage and their junctions and then 3D ultrasound imaging was done after increasing the scanning area by surface water-filled halloon method and modular method. The reconstructed image from 3D ultrasound was obtained by using tomographic ultrasound imaging and transparent mode. Results The results of 3D ultrasound imaging from 6 to 10 costal cartilages in all cases showed that solid figure of 3 costal cartilages ( 7 to 9 ) and their junctions could be demonstrated clearly , which could provide imaging support for precisely getting suitable costal cartilages for auricular framework reconstruction, thus reducing damages and waste of costal cartilages. Conclusion Application of 2D ultrasound and 3D ultrasound imaging in auricular reconstruction can demonstrate clearly the 6 to 10 costal cartilages and their junctions which can help to select suitable material as auricular framework.%目的 探讨二维和三维超声成像技术在自体耳郭支架材料-肋软骨选择中的应用.方法 选择20~29岁健康男女青年各10例,对其第6~10肋软骨及其联合部先行二维超声成像,然后用体表水囊法和模块法增加扫查面积后行三维超声成像,通过断层超声成像技术和透明成像技术获得满意的三维超声重建图.结果 对20例青年男女的第6~10肋软骨进行三维超声成像是可行的,并且能清晰显示至少3根肋软骨(主要为第7~9肋软骨)及其联合部的立体形态,为准确切取再造耳郭支架的肋软骨提供影像学支持,从而减少对肋软骨的损伤及浪费.结论 在耳郭再造术中,二维和三维超声成像技术联合应用,可清晰显示第6~10肋软骨

  19. Observation on clinical effect of auricular acupoint sticking plus music therapy for post-stroke insomnia%耳穴贴压结合音乐疗法对脑卒中后失眠的疗效观察

    Institute of Scientific and Technical Information of China (English)

    蔡晓敏; 章旭萍; 唐杏

    2015-01-01

    目的:观察耳穴贴压结合音乐疗法对脑卒中失眠的疗效。方法:将154例脑卒中后失眠患者按照随机数表法分为对照组及观察组,每组各77例。对照组接受耳穴贴压治疗,观察组在耳穴贴压的基础上结合音乐移情护理。比较两组患者疗程结束时及治疗结束3个月后的临床疗效。结果:治疗结束时,观察组总有效率为98.7%,显著高于对照组的89.6%,两组差异具有统计学意义(P<0.05);治疗结束3个月后,观察组总有效率为90.9%,显著高于对照组的80.5%,两组差异具有统计学意义(P<0.05)。结论:耳穴贴压结合音乐疗法治疗脑卒中后失眠临床疗效肯定,为制定脑卒中后失眠患者最佳护理康复干预方案提供了新思路。%Objective:To observe the clinical effect of auricular acupoint sticking plus music therapy for post-stroke insomnia. Methods:A total of 154 cases with post-stroke insomnia were randomly divided into a control group and an observation group by the random digital table, 77 cases in each group. The control group was treated by auricular acupoint sticking, while the observation group was treated by auricular acupoint sticking plus music therapy, to compare the clinical effects at the end of the treatment and three months after the treatment between the two groups. Results:At the end of treatment, the total effective rate was 98.7% in the observation group, remarkably higher than 89.6% in the control group, with a statistically significant difference between the two groups (P Conclusion:Auricular acupoint sticking plus music therapy was affirmative in the clinical effects for post-stroke insomnia, providing a new idea to design a best nursing and rehabilitative plan for the patients with post-stroke insomnia.

  20. Clonagem de canistel por estaquia

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    Fernando Marcelo Chiamolera

    2014-09-01

    Full Text Available O canistel é nativo do sul do México e América Central e seus frutos apresentam elevado teor de carotenoides e vitamina A. Sua propagação é feita via sementes, resultando em considerável variabilidade genética entre os indivíduos, sendo a propagação vegetativa preferível, a fim de fixar características desejáveis. Assim, o objetivo deste trabalho foi avaliar a propagação vegetativa por estaquia de ramos semi-herbáceos de canistel, em função de quatro genótipos e quatro concentrações de AIB. Foram utilizadas estacas semiherbáceas apicais, mantidas com um par de folhas, sob nebulização intermitente, por 120 dias. O delineamento experimental foi o inteiramente casualizado, em esquema fatorial 4×4 (genótipos de canistel × concentrações de AIB, com quatro repetições e dez estacas por parcela. Foram avaliados a porcentagem de sobrevivência, a retenção foliar, o enraizamento, o calejamento, o número e o comprimento médio de raízes por estaca. O genótipo PC-1 foi superior aos demais, em todas as variáveis avaliadas, com destaque para o enraizamento das estacas, superior a 60%. As concentrações de AIB (0; 1.000; 3.000 e 5.000 mg L-1 não influenciaram na sobrevivência, retenção foliar e enraizamento das estacas, mas aumentaram o número e o comprimento de raízes em relação ao tratamento-controle (sem AIB. Há diferença na capacidade de enraizamento das estacas entre os genótipos de canistel, sendo a melhor resposta obtida com PC-1. A concentração de 3.000 mg L-1 de AIB resulta em maior número e comprimento de raízes nas estacas de canistel.

  1. Once mil metros por segundo

    OpenAIRE

    2012-01-01

    Esta exposición es una ventana hacia el mundo de la Ciencia Ficción. Los sueños de escritores extraordinarios, personajes, lugares, máquinas y robots que cada día están más cerca de nuestra cotidianidad gracias a los avances de la ciencia y la tecnología hacen parte de la muestra itinerante por las sedes de la Universidad Nacional. El visitante puede recorrer los diferentes géneros que constituyen este género literario, además de conocer sus principales representantes. Así mismo se explor...

  2. Sepsis neonatal por Estreptococos Pyogenes

    OpenAIRE

    Gilberto Rodríguez-Herrera; Cinthya Ramírez-Navarro

    2009-01-01

    Se presenta el caso de un paciente masculino, recién nacido a término adecuado para la edad gestacional, quien nace por parto vaginal, con el antecedente de fiebre en la madre durante el periodo de postparto inmediato. Los padres consultan a los 2 días de vida pues le notan dificultad respiratoria, hipoactividad y rechazo a la leche materna. El paciente se interna y se aborda como una sepsis. Durante su estancia en el servicio de neonatología del Hospital Nacional de Niños asocia fallo respir...

  3. Miasis ocular por Oestrus ovis

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    María Beltrán F

    2006-01-01

    Full Text Available Se presentan tres casos de miasis ocular (dos adultos y un niñoprocedentes de zonas ganaderas de la provincia de Huaura,departamento de Lima,que acudieron al Hospital Regional de Huacho por presentar el ojo rojo,fotofobia, edema palpebral y sensación de cuerpo extraño;se extrajeron larvas adheridas al canto interno del ojo,las cuales se recibieron en el Instituto Nacional de Salud y fueron identificadas como Oestrus ovis .

  4. Auricular acupuncture for insomnia: a randomized controlled trial%耳穴贴压疗法治疗失眠症的随机对照研究

    Institute of Scientific and Technical Information of China (English)

    姜斌; 马朱红; 左芳

    2010-01-01

    Objective To investigate the effect of auricular acupuncture therapy (AAT) and standardized acupoints on sleep parameters among people with insomnia. Methods A single-blind,randomized pilot study where the treatment group AAT on active points and the control group received AAT on sham points during a 4-week treatment period. Participants were recruited from the Acupuncture Outpatient Clinics in the General Hospital of People' s Liberation Army. In all, 125 patients were included in the study, with 63 in treatment group and 62 in control group. Sleep parameters were obtained by using the Pittsburgh Sleep Quality Index (PSQI). Results (1)Significant improvement in the PSQI total score and seven components score including sleep quality,time on falling asleep, sleeping time, efficiency and disorder of sleep, hypnotic and daytime functional disorder after treatment in both treatment group and control group (P<0.01). (2) After treatment, there was a statistically significant difference seen in the PSQI total score and six components score (P<0.01) except for hypnotic between the two groups. There were statistically significant differences in the rank differential value of total score and seven components of two groups (P<0.01). (3) There were statistically significant differences in the mean rank of PSQI seven components using Mann-Whitney test (P<0.01). Conclusion Evidence was found to support the hypothesis that AAT played an effective role in improving the quantity and quality of sleep in those subjects with insomnia. A standardized AAT might help the treatment of insomnia, especially when combined with other treatments as psychological and behavioral therapies.%目的 探讨耳穴贴压疗法及特定穴位治疗失眠症的有效性.方法 选择符合纳入标准的失眠症患者125例,随机分为真穴治疗组63例和伪穴对照组62例.真穴组选取神门、皮质下、心、肾、肝、脾、枕等穴位,伪穴组选上述穴位旁开2~3mm

  5. Polioencefalomalacia experimental em bovinos induzida por toxicose por enxofre

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    Paulo H.J. Cunha

    2011-01-01

    Full Text Available O presente trabalho teve como objetivos avaliar os sinais clínicos, as concentrações do sulfeto de hidrogênio ruminal e as alterações anatomopatológicas associadas à intoxicação experimental por enxofre em bovinos. Foram utilizados dez bezerros mestiços leiteiros, sendo que quatro bovinos ingeriram ração sem sulfato de sódio (G1 e seis consumiram ração com sulfato de sódio (G2. Exames clínicos (temperatura retal, frequência cardíaca e respiratória e motricidade ruminal e laboratoriais (hemograma, fibrinogênio, proteína plasmática, pH do fluido ruminal, concentração do sulfeto de hidrogênio ruminal, líquido cerebrospinal e histopatológico foram realizados. A temperatura retal, frequência cardíaca, hemograma, fibrinogênio, proteína plasmática, pH do fluido ruminal e os valores do líquido cerebrospinal estavam dentro dos valores de referência para a espécie. Taquipnéia, hipomotricidade ruminal e elevados valores de sulfeto de hidrogênio ruminal foram observados nos bezerros do grupo G2. Um bezerro do grupo G2 apresentou sinais neurológicos e lesões histopatológicas de PEM. Dois animais de cada grupo foram eutanasiados. Lesões microscópicas foram observadas nos bezerros do G2. Histologicamente as alterações observadas foram necrose neuronal cortical e lesões hemorrágicas nos núcleos basais, tálamo, mesencéfalo, ponte e bulbo. O protocolo experimental constituído por uma dieta rica em carboidrato de alta fermentação, baixa quantidade de fibra efetiva e altos níveis de enxofre (0,52% ocasionou alterações clinicas e histológicas e elevadas concentrações de sulfeto de hidrogênio ruminal compatíveis com quadro de intoxicação por enxofre.

  6. toxicidad neuroendocrina inducida por cadmio

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    A Romero

    2008-01-01

    Full Text Available El cadmio es un agente químico tóxico importante debido a su creciente nivel en el medio ambiente como resultado de prácticas industriales y agrícolas. Como perturbador endocrino, el cadmio modifica la secreción de hormonas hipofisarias. Los efectos indirectos del cadmio provocan la generación de especies reactivas de oxígeno y reducen la actividad de las proteínas implicadas en las defensas antioxidantes. La melatonina es conocida como un potente antioxidante, scavenger de radicales libres y quelante de metales sintetizada en la glándula pineal. De esta manera, las acciones antioxidantes de esta indolamina protegen frente a la peroxidación lipídica y el daño oxidativo de los radicales y de sus productos tóxicos. Los trabajos recopilados en esta revisión ponen de manifiesto la capacidad antioxidante de la melatonina y, por lo tanto, su posible papel protector frente a la toxicidad del cadmio en lo que se refiere al estrés oxidativo y peroxidación lipídica inducidos por la exposición a este metal.

  7. Hipoglucemia inducida por carcinoma adrenal

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    Jimena Soutelo

    2013-08-01

    Full Text Available El carcinoma suprarrenal es una neoplasia maligna infrecuente y de mal pronóstico. La presentación clínica más común es originada por la producción hormonal excesiva, mientras que el desarrollo de hipoglucemia sintomática es excepcional. Presentamos el caso de una mujer de 37 años que ingresó al hospital por síntomas de hipoglucemias graves, hipertensión arterial, hipopotasemia y amenorrea secundaria. En el laboratorio se halló hipoglucemia con insulina inhibida y niveles de andrógenos en rango tumoral. La tomografía computarizada (TC de abdomen y pelvis mostró voluminosa formación heterogénea de aspecto sólido sin plano de clivaje con respecto al parénquima hepático e intenso realce con contraste. Luego de la extirpación de la masa retroperitoneal, evolucionó con valores de glucemia y potasemia normales, estabilizó la presión arterial y recuperó los ciclos menstruales.

  8. Implant-supported auricular prosthesis

    OpenAIRE

    Aditi Nanda; Veena Jain; Rakesh Kumar; Krishna Kabra

    2011-01-01

    Differences in the balance of shape, size, and position of body organs are immediately perceived as "looking wrong" and this perception can subject the individual to significant peer ridicule and social ostracism, often expressing as intense shame and anguish in the attitude of the afflicted. Rehabilitation of such patients can be remarkably beneficial on the individual′s self-esteem and body image. The onus of the deed lies in the hands of a team that combines artistic excellence with surgic...

  9. Mortalidad intrahospitalaria por accidente cerebrovascular

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    Federico Rodríguez Lucci

    2013-08-01

    Full Text Available La mortalidad global por accidente cerebrovascular (ACV ha disminuido en las últimas tres décadas, probablemente debido a un mejor control de los factores de riesgo vascular. La mortalidad hospitalaria por ACV ha sido tradicionalmente estimada entre 6 y 14% en la mayoría de las series comunicadas. Sin embargo, los datos de ensayos clínicos recientes sugieren que esta cifra sería sustancialmente menor. Se revisaron datos de pacientes internados con diagnóstico de ACV del Banco de Datos de Stroke de FLENI y los registros institucionales de mortalidad entre los años 2000 y 2010. Los subtipos de ACV isquémicos se clasificaron según criterios TOAST y los ACV hemorrágicos en hematomas intrapanquimatosos, hemorragias subaracnoideas aneurismáticas, malformaciones arteriovenosas y otros hematomas intraparenquimatosos. Se analizaron 1514 pacientes, 1079 (71% con ACV isquémico (grandes vasos 39%, cardioembólicos 27%, lacunares 9%, etiología indeterminada 14%, otras etiologías 11% y 435 (29% con ACV hemorrágico (intraparenquimatosos 27%, hemorragia subaracnoidea 30%, malformaciones arteriovenosas 25% y otros hematomas espontáneos 18%. Se registraron 38 muertes intrahospitalarias (17 ACV isquémicos y 21 ACV hemorrágicos, representando una mortalidad global del 2.5% (1.7% en ACV isquémicos y 4.8% en ACV hemorrágicos. No se registraron muertes asociadas al uso de fibrinolíticos endovenosos. La mortalidad intrahospitalaria en pacientes con ACV isquémico y hemorrágico en nuestro centro fue baja. El manejo en un centro dedicado a las enfermedades neurológicas y el enfoque multidisciplinario por personal médico y no médico entrenado en el cuidado de la enfermedad cerebrovascular podrían explicar, al menos en parte, estos resultados.

  10. 颞浅动脉蒂跨耳后动脉逆行岛状耳廓复合组织瓣修复鼻翼缺损%Repairing alar defects by using a retro-grade island auricle composite tissue flap based on the interconnection of superficial temporal artery and posterior auricular artery

    Institute of Scientific and Technical Information of China (English)

    陈石海; 韦强; 廖明德; 刘庆丰; 于海生

    2009-01-01

    Objective To investigate the application of reverse island auricular composite tissue flap based on the superficial temporal artery for alar defects. Methods 16 cases with alar defects were treated with reverse island auricular composite tissue flap based on the superficial temporal artery. Results All the composite auricular flaps survived with primary heMing. The patients were followed up for half a year to four years. The survived composite flaps had a similar color, texture and appearance as normal alar. The cosmetic result was satisfactory. Conclusions Reverse island auricular composite tissue tlap based on the superficial temporal artery is very suitable for alar defects.%目的 探讨应用颢浅动脉蒂跨耳后动脉逆行岛状耳廓复合组织瓣修复鼻翼缺损的方法.方法 对16例鼻翼缺损患者,应用颞浅动脉蒂跨耳后动脉逆行岛状耳廓复合组织瓣移植修复.结果 全部病例移植的带蒂耳廓复合组织瓣完全成活,伤口一期愈合.最长随访4年,最短半年,移植的耳廓复合组织瓣的形态、颜色和质地与正常鼻翼相似,效果满意.结论 应用颞浅动脉蒂跨耳后动脉逆行岛状耳廓复合组织瓣修复鼻翼缺损,是一种理想的修复方法.

  11. Estenosis de venas pulmonares post ablación por radiofrecuencia Pulmonary vein stenosis after radio frequency ablation

    Directory of Open Access Journals (Sweden)

    Marcelo Guzzi

    2011-06-01

    Full Text Available Es importante estar atento ante la aparición de síntomas respiratorios luego de la realización de un procedimiento de ablación por radiofrecuencia en el tratamiento de la fibrilación auricular, pues la estenosis de venas pulmonares (EVP tiene una incidencia de entre 1 y 3% y puede aparecer hasta en los dos años posteriores al procedimiento1. Presentamos el caso de un paciente de 41 años de sexo masculino, que ingresó por un cuadro de hemoptisis y toracodinia de tres semanas de evolución, con antecedente de ablación por radiofrecuencia 6 meses antes de la admisión. La angiotomografía no evidenció tromboembolismo pulmonar (TEP y la angiorresonancia detectó hipoperfusión deI lóbulo superior del pulmón izquierdo (LSI. Debido a los antecedentes de ablación se solicitó angiotomografía de venas pulmonares, que evidenció estenosis de la vena del LSI. Se realizó estudio hemodinámico con dilatación y colocación de stent.Physicians should be alert to the occurrence of respiratory symptoms after radio frequency ablation for the treatment of atrial fibrillation. Pulmonary veins stenosis could appear with an incidence of between 1and 3% during the two years following the procedure. We present the case of a 41year-old-male patient admitted with a three weeks old hemoptysis and thoracodinia and a prior history of a radiofrecuency ablation procedure performed six months earlier. The angiotomography was not compatible with the diagnosis of pulmonary embolism and the angio-MRI detected hypoperfusion of the left upper pulmonary lobe. Consequently pulmonary veins angiotomography was requested, showing upper pulmonary lobe vein stenosis. An hemodynamic study with vein expansion and stent placement was successfully performed.

  12. Miotoxicidade por organofosforados Organophosphate myotoxicity

    Directory of Open Access Journals (Sweden)

    Maria J. Cavaliere

    1996-06-01

    Full Text Available Os organofosforados são um grupo de compostos químicos amplamente utilizados em agropecuária como inseticidas, ocasionando intoxicações acidentais em animais e humanos, e mesmo sendo utilizados em tentativas de suicídio. A toxicidade desses produtos decorre sobretudo de insuficiência cárdio-respiratória por compromentimento do sistema nervoso autônomo. Sabe-se que alguns destes compostos induzem em animais de experimentação e em humanos, uma miopatia caracterizada por degeneração de células musculares, comprometendo sobretudo a musculatura respiratória. Baseado no fato de que este comprometimento contribui para a piora da função respiratória, propõe-se um protocolo de avaliação rotineira de miotoxicidade por compostos organofosforados, através de uma bateria mínima e suficiente de colorações e reações histoquímicas para quantificação da necrose muscular. Utilizaram-se como modelo experimental, grupos de ratos albinos (Wistar intoxicados com o organofosforado paraoxon, com e sem antídotos (atropina ou pralidoxima. Verificou-se nos grupos tratados com paraoxon e paraoxon mais atropina, necrose de fibras musculares no diafragma, que atingia em determinadas áreas até 15% das fibras. No grupo tratado com paraoxon mais pralidoxima, a necrose foi mínima, evidenciando o papel mioprotetor deste último antídoto.Organophosphates comprise a group of chemical compounds extensively used in farming as insecticides, which cause accidental poisoning in animals and men and are also used in suicide attempts. The toxicity of these compounds is due especially to the cardiac and respiratory impairment in consequence of autonomic nervous system disorders. However, it is known that some of these products induce a myopathy in experimental animals and humans. This myopathy is characterized by muscle cell degeneration, involving above all the respiratory muscles. Based on the fact that this involvement certainly enhances the

  13. Effect of nematodes in edible mushroom substance on hypha growth of Auricularia auricular and its quantity threshold%双孢蘑菇基质中线虫影响木耳菌丝生长的数量阈值

    Institute of Scientific and Technical Information of China (English)

    谢飞; 刘奇志; 梁林琳; 杨道伟

    2012-01-01

    Based on the former study related to the reproduction and impact on hypha growth of three dominant nema-tode species isolated from edible mushroom growing substance, the effect of nematode density ( 5 , 10, 20, 40, 80, 160 individuals per tube) on hypha growth of Auricularia auricular was investigated to find out the quantity threshold. The results showed that there was no obvious difference in hypha appearance of Auricularia auricular, compared with the control with the nematodes, Mesorhabditis sp. at the density of 5 and 10 individuals per tube after 2 weeks of inoculation. The amount of reproduction were 40 and 255 individuals per tube, respectively. The hypha appearance of A. auricular was slightly different after 3 weeks of inoculation. With the nematodes of Acrobeloides sp. and Aphe-lenchoides composticola Franklin at the density of 5 individuals per tube after 2 weeks of inoculation, the hypha appearance became yellow. The amount of reproduction were 55 and 93 individuals per tube, respectively. After 3 weeks, the hypha became brown, and half of it was bitten. The hypha was seriously affected at the tested densities of more than 20 individuals per tube of all the three species of nematodes. The hypha was bitten up almost after 3 weeks of inoculation. Therefore, for mushroom production, the amount of above 3 nematodes should be less than 5 individuals per tube (about 8 individuals per 100 g) in mushroom growing substance.%在研究了双孢蘑菇生产基质中的3种优势线虫数量扩增及对菌丝生长影响的基础上,着重研究了线虫密度(5,10,20,40,80,160条·管-1)对木耳菌丝生长的影响,以确定该3种线虫的数量影响阈值.结果表明:中杆属(Mesorhabditis sp.)线虫在密度为5和10条·管-1的条件下,接种2周后,菌丝表观与对照的无明显不同,繁殖量分别达40和255条·管-1;接种3周后,菌丝表观略有变化.拟丽突属(Acrobeloides sp.)和滑

  14. 骨整合义耳修复全耳廓缺损的远期疗效观察%Long-term therapeutic effects of repairing the whole auricular defects with osseointegrated prosthetic ears

    Institute of Scientific and Technical Information of China (English)

    张志钢; 陈穗俊; 郑亿庆; 陈斌; 陈洽鑫

    2010-01-01

    Objective To evaluate the long-term therapeutic effects of repairing the whole auricular defects with osseointegrated prosthetic ears. Methods From January 2002 to December 2005, 62 patients (63 ears) with the whole auricular defects were treated with osseointegrated prosthetic ears and followed up for 5- 8 years (median 6.5 years) after operations. In all cases, the following items were analyzed: stability and dislocation rate of the implants fixing prosthetic ears, infection of tissues surrounding implants, time and appearance satisfaction of wearing prosthetic ears, rate and time length of replacement of prosthetic ears, and presence of systemic complications or not. Results All 63 ears were healed with one surgery, with the appearances of life like shapes, stable fixation, and natural color. Infection of implants and their surrounding tissues occured in all cases, but didn't influence the stability of the implants. All 126 implant particles in 63 ears survived after one surgery, execpt that 4 implant particles were dislocated by trauma. In all cases, the time of wearing prosthetic ears was more than 8 hours per day. Because of color fading and breakage, average time length of replacement of prosthetic ears was 3.0 years. There were no intracranial or systemic complications. Conclusions Osseointegrated prosthetic ears can be used in the treatment of the patients with the whole auricular defects, because of its safety and reliability, the stability of long-term therapeutic effects, and the good satisfaction of the patients.%目的 探讨骨整合义耳修复全耳廓缺损的远期疗效.方法 回顾性分析中山大学附属第二医院耳鼻咽喉头颈外科自2002年1月至2005年12月行骨整合义耳修复耳廓缺损患者62例(63耳),随访5~8年,中位随访时间6.5年.就其固位义耳种植体的稳定性、脱出率,种植体周围组织感染,配戴义耳时间和外观满意度,义耳更换频率和周期及有无全

  15. Analysis of 54 cases of amblyopia of children treated by using Huaiqihuang Granules combined with Auricular Point Pressing%槐杞黄颗粒合耳穴贴压治疗儿童弱视54例分析

    Institute of Scientific and Technical Information of China (English)

    郭建玲; 余凤慈; 梁淑贞

    2010-01-01

    Objective To observe the effect of the therapy of using Huaiqihuang Granules combined with Auricular Point Pressing for children in amblyopia. Methods Amblyopia in children of our clinic as a treatment group (54 cases, total 88 eyes), the treatment group was treated by using Huaiqihuang Granules combined with Auricular Point Pressing. The control group was treated by using SI LI BA combined with major amblyoscope (46 cases, total 76 eyes). And analysing the amblyopia type, the degree of amblyopia, the nature of amblyopia watch. Results The basic cure rate and total effective rate in treatment group were 65.9% and 95.5%, and its in control group were 50% and 84.2%. Between two groups,the basic cure rate of treatment group was significantly better than that in control group (P< 0.05). The effect of treatment was better for the ametropic and anisometropic amblyopia, center fixation, but it was poor in strabismic amblyopia, paracentral fixation. The lighter degree of amblyopia had the better effect. Conclusions Compared with western medicine, traditional chinese medicine shows outstanding advantages in treatment, Huaiqihuang Granules combined with Auricular Point Pressing is an safe and effective TCM therapy for the children with amblyopia, the therapy has convenient usage, fast and remarkable effect, which is worth clinical application and further study.%目的 观察槐杞黄颗粒合耳穴贴压治疗儿童弱视的疗效.方法 2006年1月至2009年6月本院门诊确诊为弱视的儿童共计100例,随机分为治疗组和对照组,治疗组54例(88眼),采用槐杞黄颗粒联合耳穴贴压治疗.对照组46例(76眼),采用思利巴联合同视机治疗.分析比较两组弱视的类型、弱视程度、弱视注视性质.结果 治疗组基本治愈率和总有效率为65.9%、95.5%,对照组基本治愈率和总有效率为50%、84.2%.两组比较,治疗组的基本治愈率明显优于对照组(P<0.05).临床显示屈光不正性和屈光参差

  16. 耳穴贴压对肝移植患者术后睡眠质量的干预研究%Study on the Effect of Auricular Point Sticking on Sleep Quality of Patients Undergone Liver Transplantation

    Institute of Scientific and Technical Information of China (English)

    殷蓉; 高军; 陶艳; 杨建鑫; 高俊芳; 秦珊

    2014-01-01

    Objective To observe the effect of auricular point sticking on the sleep quality of patients undergone liver transplantation.Method The sleep quality was assessed by using sleep quality scale. The patients undergone liver transplantation were randomized into two groups, both receiving auricular point sticking, while the insomnia zone was selected in the observation group and non-insomnia zone was selected in the control group, 4 weeks as a treatment course.Result In 4 weeks after the transplantation, there were significant inter-group differences in comparing the scores of unfreshing sleep, difficulty falling asleep, nightmairs, medications, post-insomnia reactivity, and the total score of the self-rating scale of sleep (SRSS) (P0.05).Conclusion Auricular point sticking at the insomnia zone can markedly improve the short-term sleep disorder in patients after liver transplantation, and can reduce the dose of sleep medications.%目的观察耳穴贴压疗法对肝移植患者术后睡眠质量的干预效果。方法采用睡眠量表对肝移植者术后睡眠质量进行测评,随机分为两组,两组均采用耳穴贴压法进行干预,试验组失眠治疗区取穴,对照组非失眠治疗区随机取穴,疗程为4星期。结果术后4星期内两组觉醒不足、入睡困难、恶梦夜惊、服药情况、失眠后反应及SRSS总分等指标比较差异有统计学意义(P<0.05),术后2个月内,两组入睡时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍及PSQI总分等指标比较差异有统计学意义(P<0.05),说明试验组睡眠质量有显著提高。术后3个月两组睡眠指标比较差异无统计学意义(P>0.05)。结论失眠治疗区行耳穴贴压法对肝移植患者术后短期睡眠紊乱有明显改善作用,可减少安眠药物的使用。

  17. La inconstitucionalidad por omisión

    Directory of Open Access Journals (Sweden)

    Luz Bulnes Aldunate

    2006-01-01

    Full Text Available El artículo analiza la facultad de los tribunales constitucionales para determinar la inconstitucionalidad por omisión, en virtud del silencio u omisión de la autoridad de normar un principio o regla constitucional dispuesto por la Constitución explícita o implícitamente.

  18. Verdad por definición

    Directory of Open Access Journals (Sweden)

    Garrido Garrido, Julián

    1997-07-01

    Full Text Available Not available.La verdad por definición es un tipo peculiar de verdad científica, distinguible de las verdades lógicas, matemáticas y empíricas. La definición, por su parte, designa diversos procedimientos de asignación de significado, cuyas diferencias exigen una adjetivación cuidadosa: definiciones ostensivas y operacionales, definiciones de diccionario y definiciones teóricas. Pero sólo las del último tipo son verdaderas por definición. En el presente artículo se precisa el concepto formal de definición teórica, se delimita la estructura de esos enunciados, se analiza la verdad por definición, y se comparan, por último, las definiciones teóricas con los otros tipos de definición.

  19. Evolution of NADPH-cytochrome P450 oxidoreductases (POR) in Apiales - POR 1 is missing

    DEFF Research Database (Denmark)

    Andersen, Trine Bundgaard; Hansen, Niels Bjørn; Laursen, Tomas;

    2016-01-01

    The NADPH-dependent cytochrome P450 oxidoreductase (POR) is the obligate electron donor to eukaryotic microsomal cytochromes P450 enzymes. The number of PORs within plant species is limited to one to four isoforms, with the most common being two PORs per plant. These enzymes provide electrons to ...

  20. Anticoagulación en fibrilación auricular y antiagregación en diabetes mellitus tipo 2: ¿Cómo lo hacemos? Anticoagulation in atrial fibrillation and antiplatelet in diabetes mellitus type 2: How do we do it

    Directory of Open Access Journals (Sweden)

    M.P. Arroyo

    2007-04-01

    Full Text Available Fundamento: A pesar de la evidencia sobre el interés de anticoagular en Fibrilación Auricular (FA y antiagregar a los diabéticos (DM tipo 2, las referencias nacionales e internacionales hablan de un bajo nivel de asunción de esos criterios en la práctica. Navarra no dispone de estudios publicados sobre estos aspectos. Material y métodos: Estudio descriptivo transversal. Población: consulta de atención primaria (1600 personas 15 años. Criterios de inclusión: pacientes con diagnóstico de FA/ con diagnóstico de DM tipo 2 mayores de 40. Variables: edad y sexo, criterios de FA con alto riesgo embólico (6% anual y factores de RCV en DM2. Recogida de datos: en registro informatizado de Organitation and Management Information (OMI. Análisis: (estudiado el universo poblacional, resultados en números absolutos y porcentajes. Resultados: Veinticinco personas con diagnóstico de FA crónica (14 mujeres y 11 hombres, edad media 78,36 años; 22 (81,8% presentan alto riesgo embólico. Hubo contraindicaciones en 4 casos. Los diabéticos tipo 2 suman 69 personas (29 mujeres y 40 varones, edad media 68,57 años. En prevención primaria (PP hay 16 (23,1%, en prevención secundaria (PS 26 (37,3%, y no llevan tratamiento antiagregante 27 (39,1%. Existe contraindicación en 8 casos y serían 14 (20,2% los pacientes susceptibles de intervención. Conclusiones: - Los resultados de tratamiento anticoagulante oral (TAO en FA de alto riesgo superan las referencias contratadas. - La PP con DM2 con cifras similares a otros estudios; se detecta un campo de mejora. - Debemos solicitar la opinión del paciente e individualizar estas terapias. - Importante responsabilidad del médico de familia en la prevención cardiovascular de los pacientes afectados por estos procesos.Background: In spite of evidence about the interest of anticoagulation in Atrial Fibrillation (AF and antiplatelet to diabetics (DM type 2, the national and international references describe a

  1. Verdad por definición

    OpenAIRE

    Garrido Garrido, Julián

    1997-01-01

    Not available.La verdad por definición es un tipo peculiar de verdad científica, distinguible de las verdades lógicas, matemáticas y empíricas. La definición, por su parte, designa diversos procedimientos de asignación de significado, cuyas diferencias exigen una adjetivación cuidadosa: definiciones ostensivas y operacionales, definiciones de diccionario y definiciones teóricas. Pero sólo las del último tipo son verdaderas por definición. En el presente artículo se precisa el concepto formal ...

  2. Intoxicación por Paraquat

    OpenAIRE

    Glenda Viales López

    2014-01-01

    El paraquat es un herbicida bipiridílico que actúa por contacto, se presenta en forma líquida en concentraciones del 20% para uso agrícola. Su nombre químico es eI 1-1´-dimetil-4-4- bipiridilo, con el nombre comercial de Gramoxone. La intoxicación por paraquat tiene una tasa de mortalidad elevada. La intoxicación grave se caracteriza por la afectación de múltiples órganos, principalmente los pulmones, los riñones y el hígado. El pulmón es el órgano diana en la intoxicación por paraquat y la i...

  3. 14 Nobel, preocupados por el CERN

    CERN Multimedia

    Rivera, A

    2003-01-01

    "E l presidente del Consejo del CERN (Laboratorio Europeo de Fisica de Particulas, junto a Ginebra), Maurice Bourquin, ha recibido una carta firmada por un grupo de cientificos muy especiales: 14 premios Nobel de Fisica" (1 page).

  4. Intoxicación por Paraquat

    Directory of Open Access Journals (Sweden)

    Glenda Viales López

    2014-12-01

    Full Text Available El paraquat es un herbicida bipiridílico que actúa por contacto, se presenta en forma líquida en concentraciones del 20% para uso agrícola. Su nombre químico es eI 1-1´-dimetil-4-4- bipiridilo, con el nombre comercial de Gramoxone. La intoxicación por paraquat tiene una tasa de mortalidad elevada. La intoxicación grave se caracteriza por la afectación de múltiples órganos, principalmente los pulmones, los riñones y el hígado. El pulmón es el órgano diana en la intoxicación por paraquat y la insuficiencia respiratoria con fibrosis pulmonar aguda es la causa más común de muerte.

  5. Micetoma por Nocardia brasiliensis: reporte de caso

    Directory of Open Access Journals (Sweden)

    Miriam Guevara R

    2003-07-01

    Full Text Available Se presenta el caso de un paciente peruano, agricultor, con una infección cutánea de origen traumático causada por Nocardia brasiliensis, que evolucionó hacia la amputación del miembro inferior afectado. El diagnóstico se realizó por examen directo y cultivo del espécimen.

  6. Effects of modified operation combined with secondary disc method in benign tumor of parotid gland on sensory recovery of auricular lobule and auricle skin%改良术式结合二次翻瓣法在腮腺良性肿瘤治疗中对耳垂及外耳廓区皮肤感觉恢复的影响

    Institute of Scientific and Technical Information of China (English)

    何文泽; 孙道成; 邹家华

    2015-01-01

    目的:比较腮腺良性肿瘤改良术式结合二次翻瓣法较传统术式对患者耳垂及外耳廓区皮肤感觉恢复的影响。方法选择2005年7月至2014年6月在我院行腮腺良性肿瘤切除术患者22例,随机分为实验组和对照组,每组11例。实验组行保留腮腺咬肌筋膜,二次翻瓣法,解剖并保留耳大神经耳后、耳垂支和腮腺区域性切除术的腮腺良性肿瘤改良手术方式。对照组按常规行腮腺肿瘤及腮腺浅叶或全叶切除术。术后观察、随访6个月。采用SPSS 13.0统计软件包中的检验,对两组患者术后耳垂及外耳廓区皮肤感觉恢复情况进行χ2比较。结果实验组中患者耳垂及外耳廓区感觉恢复情况明显优于对照组,差异具有显著性(P<0.05)。结论改良术式结合二次翻瓣法比传统手术方式在腮腺良性肿瘤治疗中对保存耳垂及外耳廓皮肤感觉具有明显优势。%Objective To compare the effects of modified operation combined with secondary disc method in benign tumor of parotid gland and traditional surgery on the sensory recovery of the auricular lobule and auricle skin.Methods 22 patients with parotid benign tumor who received parotidectomy in our hospital from2005.7 to 201.6 were randomly divided into experimental group ( n =11 ) and control group ( n =11 ) .In experimental group, the modified operation of benign tumor in parotid gland included regional ectomy of parotid, secondary disc method, reservation of fascia parotidea masseterica and dissection and reservation of the post aurem and auricular lobule branches of great auricular nerve.In the control group, the 11 patients were operated by the conventional technique.After 6 months, the effects of 2 groups on the sensory recovery of the skin of the auricular lobule and auricle region were evaluated.The data were analyzed with SPSS 13.0 software package for x2test. Results The sensory recovery of the skin of the auricular

  7. 坎地沙坦酯联合耳穴压豆对非杓型高血压病患者的疗效观察%Candesartan Cilexetil Combined With Auricular Acupuncture Point on Curative Effect of Non-Dipper Type Hypertension Patients

    Institute of Scientific and Technical Information of China (English)

    曲玉梅; 吴华慧

    2015-01-01

    目的:观察坎地沙坦酯联合耳穴压豆对非杓型高血压患者的血压影响。方法选取70例非杓型高血压患者随机分为治疗组和对照组,对照组夜间口服坎地沙坦酯;治疗组在口服坎地沙坦酯的同时加用耳穴压豆法。结果治疗后治疗能明显降低非杓型高血压患者的舒张压及收缩压,同时坎地沙坦酯联合耳穴压豆能促使非杓型高血压患者向杓型高血压转换。结论耳穴贴压法能明显降低非杓型高血压患者的血压,疗效优于对照组。%ObjectiveObservation of candesartan in conjunction of ear beans on non-Dipper type hypertension patients' blood pressure.Methods Select 70 non-Dipper type hypertension patients were randomly divided into treatment and control groups, controls the night oral candesartan ester treatment group at the time of oral administration of candesartan ester plus Auricular bean method.Results After treatment in the treatment of non-Dipper type hypertension patients can signiifcantly reduce the systolic blood pressure and diastolic blood pressure and candesartan combined Auricular beans can induce non-Dipper type hypertension patients switch to Dipper type hypertension. Conclusion Auricular acupoint method non-Dipper type hypertension patients can signiifcantly reduce blood pressure, than the control group.

  8. Respuesta hipotensora al tratamiento agudo con péptido natriurético auricular: su relación con la expresión y la actividad de la óxido nítrico sintetasa cardíaca en ratas espontáneamente hipertensas

    OpenAIRE

    Cristina T. Arranz; Ana M. Balaszczuk; Andrea Fellet; Carolina Caniffi; Rosana Elesgaray; María A. Costa

    2007-01-01

    IntroducciónEl péptido natriurético auricular (ANP) y el óxido nítrico (NO) aumentan la diuresis y la natriuresis y disminuyen el tono vascular. Previamente demostramos que el NO está involucrado en el efecto hipotensor del ANP en ratas normotensas.ObjetivoEstudiar el efecto del ANP sobre la presión arterial media (PAM) y el sistema del NO en ratas espontáneamente hipertensas (SHR) y Wistar Kyoto (WKY) y la participación de la isoforma inducible de la NO-sintasa (iNOS).Material y métodosProto...

  9. Anticoagulación en fibrilación auricular y antiagregación en diabetes mellitus tipo 2: ¿Cómo lo hacemos? Anticoagulation in atrial fibrillation and antiplatelet in diabetes mellitus type 2: How do we do it

    OpenAIRE

    M.P. Arroyo; J. Jimbert

    2007-01-01

    Fundamento: A pesar de la evidencia sobre el interés de anticoagular en Fibrilación Auricular (FA) y antiagregar a los diabéticos (DM) tipo 2, las referencias nacionales e internacionales hablan de un bajo nivel de asunción de esos criterios en la práctica. Navarra no dispone de estudios publicados sobre estos aspectos. Material y métodos: Estudio descriptivo transversal. Población: consulta de atención primaria (1600 personas 15 años). Criterios de inclusión: pacientes con diagnóstico de FA/...

  10. 不同干预措施对战士吸烟行为的影响%Effects of psychological intervention, auricular acupuncture and smoking cessation medication on cigarette smoking behavior in soldiers: a pilot randomized controlled trial

    Institute of Scientific and Technical Information of China (English)

    姜斌; 左芳; 吴蕾; 何耀; 陈肇始; 郑家强; 林大庆

    2011-01-01

    Objective To evaluate the effects of different smoking cessation interventions on cigarette consumption for young soldiers.Methods Sixty-eight soldiers were prospectively investigated in this randomly controlled clinical trial and assigned to the psychological intervention group,auricular acupuncture group,and smoking cessation medication group.Results All the participants showed significant reduction(33.3% to 73.9%)in post-treatment cigarette consumption.The highest quit rate was found at 7 days,although this declining trend was faded over time.One-year follow-up indicated a 6-month quit rate of 16.7%,23.8% and 30.4% in three groups,respectively.Conclusion Psychological intervention,auricular acupuncture and smoking cessation medication may be effective methods of reducing cigarette consumption and improving quit rate in young soldiers.%目的 探讨和评价不同的干预措施对集体生活年轻人群吸烟行为的影响.方法 将68名吸烟战士随机分为3组,分别采取心理干预、心理干预+耳针和心理干预+药物对其吸烟行为进行干预.采用统一问卷进行基线调查,在1、3、6个月和1年进行随访,观察不同随访时点吸烟量的减少和戒烟率.结果 三组研究对象可比性较好.在1、3、6个月随访时点,各组吸烟者的吸烟量均有不同程度的下降(33.3%~73.9%).在上述各随访时点,7d时点戒烟率均较高,而持续1个月的戒烟率和持续3个月的戒炯率有随时间下降的趋势.但3组1年随访时,持续6个月的戒烟率仍可达到16.7%、23.8%、30.4%.结论 集体管理生活环境中的戒烟心理干预是年轻战士吸烟量的减少和提高戒烟成功率的有效措施之一,药物和耳针等辅助戒烟方法的使用亦有一定的促进作用.

  11. Hemorragias intracraneales de carácter evitable asociadas a anticoagulantes orales en pacientes con fibrilación auricular Avoidable intracranial hemorrhages associated with oral anticoagulants in patients with atrial fibrillation

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    A. García Luque

    2011-12-01

    Full Text Available Introducción y objetivo: El aumento de la prescripción de anticoagulantes orales ha provocado un aumento de hemorragias intracraneales, la reacción adversa más grave asociada a este grupo farmacológico. El objetivo del estudio es evaluar el carácter evitable de hemorragias intracraneales asociada a anticoagulantes orales que causan ingreso hospitalario en pacientes con fibrilación auricular. Método: Supervisión de las historias clínicas de los pacientes que ingresaron en los Hospitales Universitarios Virgen del Rocío (01/01/03 al 31/03/07 con hemorragia intracraneal y fibrilación auricular; considerando hemorragia intracraneal asociada a anticoagulantes orales aquellas con una relación ≥ posible al aplicar el algoritmo de causalidad del Sistema Español de Farmacovigilancia. Para valorar el carácter evitable de la hemorragia intracraneal se ha estudiado la relación beneficio/riesgo del uso de anticoagulantes orales. Resultados: Al menos 20/57 (35,1% hemorragias intracraneales asociadas a anticoagulantes orales pudieron ser potencialmente evitables, de las cuales en 7/20 (35% el desenlace fue mortal, presentando secuelas 8/13 (61,5% de los supervivientes. El fármaco sospechoso de interaccionar con anticoagulantes orales referenciado con mayor frecuencia fue el omeprazol, 11/57 (19%, a pesar de estar documentada esta interacción como altamente probable en la Bibliografía y en los protocolos del Hospital. Conclusiones: La relación beneficio/riesgo del uso de anticoagulantes orales, el control estricto del Índice Normalizado Internacional, junto con las posibles interacciones medicamentosas deben ser evaluadas de forma individualizada y periódicamente para minimizar el riesgo de hemorragia intracraneal, que en un porcentaje elevado de casos es una reacción adversa potencialmente evitable y mortal.Introduction and objectives: The increase in oral anticoagulants prescription has caused an increase in intracranial hemorrhages

  12. 黑木耳多糖提取及其药理活性的研究进展%Advances on polysaccharide extraction from Auricularia auricular and its pharmacological activity

    Institute of Scientific and Technical Information of China (English)

    王献友; 陈培云; 吴广臣; 赵志磊

    2012-01-01

    With pharmacological activities in blood lipid reduction, anticoagulation, anti-oxidation, anti-radiation and tumor inhibition, Auricularia auricular polysaccharide has become a popular R&D subject in the fields of food, medical and health care. After reviewing recent research progress in polysaccharide extraction and its biological activity, it has been observed that in spite of numerous extraction methods, the current industrialized extracted polysaccharide could not meet market demands due to its hot water extraction, long duration, low yield and high cost. Moreover, issues concerning pharmacological function require follow-up research, such as mechanism of action, best dosage and its path, clinical application as immunity regulator and influence of different extraction methods on pharmacological function. Therefore, for sustainable development of Auricularia auricular polysaccharide industry in future, more efforts should be made in screening and breeding high-yield strains, optimizing extraction technology, enhancing original activity by transforming natural polysaccharide, improving submerged fermentation technique, studying polysaccharide pharmacological activity, clinical application efficacy and safety.%黑木耳多糖具有降血脂、抗凝血、抗氧化、抗辐射、抑制肿瘤等生物活性,现已成为食品、医疗、保健等领域的研究热点.文章综述了近年来黑木耳多糖提取方法及其生物活性的研究进展,发现黑木耳多糖的提取方法较多,但现在工业化提取黑木耳多糖时多采用热水浸提,耗时长、产量低、成本高,无法满足市场需求;黑木耳多糖的药理作用如作用机理、给药最佳剂量和途径、作为免疫调节剂的临床应用、不同分离技术对药效作用的影响等亟待进一步研究解决.因此,今后应加强黑木耳多糖高产菌株的筛选和选育、优化多糖提取方法、改造天然多糖而增强原有活性、优化深层发酵生产

  13. Angiografia por tomografia computadorizada dos aneurismas intracranianos

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    Laureano Vinícius Santos

    2002-01-01

    Full Text Available Este trabalho foi realizado para avaliar os achados da angiografia por tomografia computadorizada, comparativamente à angiografia por subtração digital, em relação aos aneurismas intracranianos, e a possibilidade da maior utilização da angiografia por tomografia computadorizada no Brasil. Foram analisados oito pacientes que apresentavam um total de sete aneurismas não tratados e um aneurisma tratado. Houve subseqüente correlação com outros trabalhos publicados na literatura médica. Os exames foram realizados em uma clínica e em dois hospitais privados, na cidade do Rio de Janeiro, RJ. Foi demonstrada boa correlação entre os métodos estudados, em relação ao diagnóstico dos aneurismas, no acompanhamento e avaliação pré-terapêutica dessas lesões. A angiografia por tomografia computadorizada foi um exame menos invasivo, de menor custo e maior acessibilidade. Concluiu-se que a angiografia por tomografia computadorizada é um exame que deve ser utilizado com maior freqüência para avaliação nesta enfermidade.

  14. 耳穴压豆对血液透析伴失眠患者睡眠及生活质量的影响%Influence of Auricular Acupoint Bean Pressing on Insomnia and Life Quality in Hemodialysis Patient s

    Institute of Scientific and Technical Information of China (English)

    郑青海; 刘成福

    2014-01-01

    目的:探讨能有效改善维持性血液透析患者睡眠及生活质量的方法。方法将我院80例维持性血液透析伴有失眠的患者随机分为实验组和对照组,两组均接受血液透析、纠正贫血、控制血压等基础治疗,实验组在此基础上加用耳穴压豆治疗,对照组口服阿普唑仑,以8周为一个疗程,在治疗前后用匹兹堡睡眠质量指数(PSQI)及肾脏病生活质量评分(KDQOL-SF-36)观察两组的睡眠情况以及生活质量并进行比较。结果在治疗前两组患者失眠及生活质量比较无差异(P>0.05),在治疗后实验组睡眠状况以及生活质量优于对照组(P0.05) . After treatment, PSQI and KDQOL-SF-36 scores of experiment group were significantly lower and higher respectively than those of control group ( P <0.05) . Conclusion Auricular acupoint bean pressuring therapy could improve sleep and life quality of hemodialysis patients.

  15. 针刺配合耳针治疗肾绞痛疗效观察%Clinical Study on the Treatment of Renal Colic by Body and Auricular Acupuncture

    Institute of Scientific and Technical Information of China (English)

    黄乐春; 李俊雄; 洪珏

    2011-01-01

    Objective: To evaluate the clinical effects of combined acupuncture and ear-puncture in treating renal colic. Methods: Sixty subjects were randomized into an acupuncture group and a medication group, 30 in each, to receive acupuncture and Western medicine respectively. The analgesic effects and pain relief time were measured in both groups. Results: Both of the two groups got pain relieved or reduced. The total effective rate was 89.7% in the acupuncture group, significantly superior to 77.4% in the medication group (P<0.05). Conclusion: Combined body and auricular acupuncture is efficient in relieving pain in treating renal colic, and its effective rate was higher compared with medication treatment.%目的:观察针刺配合耳针对肾绞痛发作的临床疗效.方法:将60 例患者随机分为针刺组与药物组各30 例,分别运用针刺和西药进行治疗,并对两组治疗前后镇痛效果、疼痛缓解时间进行观察.结果:治疗后两组疼痛均有减轻或缓解,其中针刺组总有效率为89.7%, 药物组总有效率为77.4%, 针刺组疗效优于药物组(P<0.05).结论:针刺配合耳针治疗肾绞痛止痛迅速,效果确切,总有效率优于药物治疗.

  16. Effect of Electroacupuncture of Auricular Concha on Inflammatory Reaction in Endotoxaemia Rats%电针耳甲区对内毒素血症模型大鼠的抗炎保护作用

    Institute of Scientific and Technical Information of China (English)

    赵玉雪; 何伟; 高昕妍; 荣培晶; 朱兵

    2011-01-01

    Objective To evaluate the effect of electroacupuncture (EA) of the auricular concha (EA-AC) on serum cytokines contents and pulmonary transcription factor nuclear factor-KB (NF-KB) expression in lipopolysaccharide (LPS) induced endotoxaemia rats so as to study its mechanism underlying cholinergic anti-inflammatory efficacy. Methods Male SD rats were randomized into normal control , model (LPS), simple EA-AC, EA-AC+ LPS, vagal nerve stimulation (VNS) + LPS, and EA-Zusanli (ST 36) + LPS groups (n = 12/group). Endotoxaemia model was duplicated by intravenous (tail vein) injection of LPS (0.5 mL/kg). Two intradermal needles were inserted into the central sites of the cavity of concha and cymba of auricular concha respectively on each side and stimulated electrically by using an electrical stimulator (i. e., EA-AC). VNS was applied to the left cervical vagal nerve, and EA (1 mA, 10 Hz, pulse-width 1 ms) was also applied to bilateral "Zusanli" (ST 36). Serum cytokines (TNF-α, IL-6) contents 2 h after modeling were determined by using enzyme linked immunosorbent assay (ELISA), and pulmonary NF-κB p 65 expression 2 h after modeling was detected by using western blotting. Results Compared with the normal control group, serum TNF-α and IL-6 contents, and pulmonary NF-KB p 65 expression level in the model group were increased significantly (P<0.01). In comparison with the model group, serum TNF-α contents in the simple EA-AC, EA-AC+ LPS, VNS+ LPS and ST 36+ LPS groups, and serum IL-6 contents and pulmonary NF-KB p 65 expression levels in the simple EA-AC, EA-AC+ LPS and VNS + LPS groups were down-regulated considerably ( P<0.05, P<0.01). Compared with the VNS+ LPS group, serum TNF-αand IL-6 contents, and pulmonary NF-KB p 65 expression level in the ST 36+LPS group were increased significantly (P<0.05,P<0. 01). In comparison with the EA-AC+LPS group, pulmonary NF-κB p65 expression level in the ST36+LPS group was increased remarkably (P<0.05). Conclusion

  17. La orejuela izquierda como fuente de accidentes cerebrovasculares: cerrar (y cómo, o no cerrar (y por qué Left atrial appendage as a source of stroke: to close (and how, or not to close (and why

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    R. Hernández-Estefanía

    2012-04-01

    Full Text Available La orejuela izquierda se considera la principal fuente de émbolos en los accidentes cerebrovasculares que se producen en pacientes con fibrilación auricular. El tratamiento con anticoagulantes orales reduce significativamente el riesgo de accidentes embólicos cerebrales en relación con la aspirina, pero se asocia a riesgo de complicaciones hemorrágicas, por lo que no siempre son utilizados. Se ha descrito que el cierre de la orejuela izquierda reduce la tasa de accidentes tromboembólicos y en la actualidad se recomienda en pacientes en fibrilación auricular sometidos a cirugía mitral, pero la formación de émbolos en estos pacientes puede deberse a otras causas, y la implicación de la orejuela podría ser menor de la que se presupone. Además, no todos los pacientes son candidatos para la anticoagulación oral, y no todos se mantienen en un rango terapéutico adecuado, lo que podría justificar la formación de trombos auriculares. Existen diversos métodos para el cierre de la orejuela: sutura directa, exclusión epicárdica mediante grapadora o clip, u oclusión mediante los recientes dispositivos endovasculares de aplicación percutánea. Pero, según la bibliografía, la efectividad de estos métodos para ocluir completamente la orejuela, así como su seguridad y eficacia para la prevención de accidentes embólicos cerebrales, pueden presentar resultados dispares. Para aumentar la controversia, algunos métodos de cierre con sutura no revelan un claro beneficio e, incluso, en algunos se describe un aumento del riesgo de tromboembolismo. Se presenta una revisión sobre la necesidad de cierre de la orejuela izquierda para la prevención de accidentes vasculares cerebrales, así como los diversos procedimientos descritos.Left atrial appendage is considered the main source of emboli in stroke for patients with atrial fibrillation. Oral anticoagulant therapy significantly reduces the risk of cerebral embolic events as compared with

  18. La conquista de Niebla por Alfonso X

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    García Sanjuán, Alejandro

    2000-01-01

    La conquista de Niebla en 660 H/1262 d.n.e. por el rey Alfonso X (1252-1284) puso fin a los cinco siglos y medio de Historia andalusí de dicha ciudad, largo período iniciado desde su sumisión por `Abd al- c Aziz b. Milsá en 94/713, al comienzo de la irrupción islámica en la Península Ibérica. Se trata, por lo tanto, de un episodio de gran relevancia en el devenir histórico de esta localidad, que ya desde época visigoda fue el principal núcleo urbano del territorio onubens...

  19. Neumopericardio debido a herida por arma blanca

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    Samuel I. Merino Barrera

    2015-10-01

    Full Text Available Hombre de 24 años de edad que ingresó en el hospital debido a una herida por arma blanca penetrante en el hemitórax derecho. La herida, de 3 cm a nivel de la piel, se localizaba a nivel del segundo espacio intercostal derecho y la radiografía de tórax demostró un neumotórax del mismo lado y una colección radiotransparente, por debajo del pericardio parietal, desde el origen de los grandes vasos hasta la porción apical del ventrículo izquierdo.

  20. Neumopericardio debido a herida por arma blanca

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    Samuel I. Merino Barrera; Francisco L. Moreno-Martínez

    2015-01-01

    Hombre de 24 años de edad que ingresó en el hospital debido a una herida por arma blanca penetrante en el hemitórax derecho. La herida, de 3 cm a nivel de la piel, se localizaba a nivel del segundo espacio intercostal derecho y la radiografía de tórax demostró un neumotórax del mismo lado y una colección radiotransparente, por debajo del pericardio parietal, desde el origen de los grandes vasos hasta la porción apical del ventrículo izquierdo.

  1. Endoftalmite por Candida albicans Candida albicans endophthalmitis

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    Pedro Duraes Serracarbassa

    2003-10-01

    Full Text Available O autor descreve os aspectos epidemiológicos, histopatológicos e clínicos da endoftalmite endógena por Candida albicans. Apresenta ainda novos métodos diagnósticos e opções terapêuticas utilizadas no tratamento das infecções fúngicas intra-oculares, por meio de revisão bibliográfica.The author describes epidemiological, histopathological and clinical aspects of endogenous Candida albicans endophthalmitis. He also presents new diagnostic methods and therapeutical options to treat intraocular fungal infections, based on literature review.

  2. PANORAMA LATINOAMERICANO DEL PAGO POR SERVICIOS AMBIENTALES

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    González T. Ángela

    2008-07-01

    Full Text Available Este documento busca proveer al lector de algunos elementos para el análisis y reflexión en torno al pago por servicios ambientales. Para ello, en primera instancia, aborda algunos conceptos básicos relacionados con economía ambiental, seguido de temas como la valoración económica de servicios ambientales y la implementación de mecanismos de pago por algunos de ellos. Lo anterior esta enriquecido con experiencias o estudios de caso a nivel latinoamericano y colombiano.

  3. Choque séptico por ehrliquiosis

    OpenAIRE

    Viviana Hernández-de Mezerville; Juan I Padilla-Cuadra

    2007-01-01

    La ehrliquiosis humana es una infección zoonótica transmitida por "garrapatas duras" causada por Anaplasma sp y Ehrlichia sp. Puede presentarse como un cuadro pseudogripal con fiebre, malestar general, mialgias y cefalea o hasta un choque séptico con falla multiorgánica y muerte. La mitad de los pacientes requieren atención hospitalaria en algún momento y se reporta una mortalidad de hasta el 5% secundaria a enfermedades oportunistas o a hemorragias. El diagnóstico se puede sospechar visualiz...

  4. Pedro Teixeira y su viaje por Mesopotamia

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    Fuente del Pilar, José Javier

    2005-04-01

    Full Text Available Pedro Teixeira es un integrante notable de la ilustre nómina de los viajeros portugueses que, a finales del s, XVI y principios del XVII, ensancharon para Occidente las fronteras del mundo. Su conocimiento en España se debe a la publicación en 1994 de su obra «Relaciones del Origen, Descendencia y Sucesión de los Reyes de Persia, y de Harmuz, y de un viaje hecho por el autor dende la India hasta Italia por tierra», en edición realizada por el profesor Eduardo Barajas Sala, lamentablemente fallecido en 1997. En este artículo se ofrece una reseña biográfica de Pedro Teixeira, y un análisis del viaje narrado por el autor en la última parte de sus «Relaciones »: el que desde Ormuz le conducirá, a través de Mesopotamia, hasta la costa del Mediterráneo.…

  5. Surto de intoxicação por sal em ovinos no estado do Pará

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    Marcos D. Duarte

    2014-11-01

    Full Text Available O presente trabalho relata um surto de intoxicação por sal em ovinos no Brasil, em uma propriedade no estado do Pará. De um total de 545 ovinos, oito animais adoeceram (1,46% e quatro destes morreram (50%. A avaliação das instalações e do manejo indicaram como fatores predisponentes a ingestão excessiva de mistura mineral e a restrição hídrica. Os principais sinais clínicos foram decúbito, diminuição ou ausência da sensibilidade cutânea, ausência dos reflexos de ameaça, palpebral e auricular, midríase, nistagmo, opistótono, espasticidade de membros, sonolência e estupor. Havia ainda, timpanismo, diarreia, taquipneia, taquicardia, desidratação e poliúria. A evolução do quadro clínico nos animais que morreram variou de duas horas e meia a 48 horas. As médias das concentrações séricas de sódio e de potássio de 31 ovinos do mesmo lote afetado pela intoxicação, em amostras colhidas durante o surto, revelaram hipernatremia (190mEq/l e hipercalemia (8,2mEq/l. À necropsia, observou-se em um animal, achatamento das circunvoluções cerebrais. Microscopicamente, neste animal, evidenciou-se vacuolização moderada do neurópilo, particularmente nas lâminas intermediárias do córtex cerebral, com aumento dos espaços perineural e perivascular. Nessas áreas foram observados ainda, acentuada tumefação e edema dos astrócitos e necrose neuronal aguda. A dosagem de sódio no encéfalo de um ovino, revelou-se elevada com valor de 3.513ppm. O diagnóstico foi realizado com base na epidemiologia, nos sinais clínicos, nas lesões macro e microscópicas e nas dosagens de sódio no soro e no encéfalo dos ovinos.

  6. 耳针联合神经生长因子对拟AD大鼠学习记忆能力的改善作用研究%Combination of auricular needling and nerve growth factor treatment improves learning and memory abilities in Alzheimer's disease model rats

    Institute of Scientific and Technical Information of China (English)

    苗婷; 刘子艳; 刘玉媛; 刘宏宇; 刘源

    2016-01-01

    目的 观察耳穴针刺和神经营养因子(NGF)联合应用对拟AD大鼠学习记忆能力的影响,并探讨其可能的机制. 方法 雄性SD大鼠40只按照随机数字表法分为对照组、模型组、耳针组及联合组,每组10只.后3组大鼠海马CA1区注射冈田酸建立拟AD大鼠模型;耳针组和联合组大鼠在此基础上用无菌针灸针埋人大鼠冈田酸注射侧耳肾、脑穴位,每日捻针1次,每次1min,共4周;联合组大鼠在冈田酸注射完毕后,于侧脑室注入0.1 g/L的NGF 5 μL,每隔1天同样剂量注射1次,共5次.观察各组大鼠Morris水迷宫行为学改变,流式细胞仪检测海马细胞凋亡,免疫组化染色方法观察胶质神经纤维蛋白(GFAP)和胆碱乙酰转移酶(ChAT)的表达,Bielschowsky染色观察神经原纤维缠结(NFT),表达Western blotting法检测海马Tau蛋白在Ser396位点(Tau-Ser396)磷酸化程度. 结果 与耳针组比较,联合组Morris水迷宫定向航行实验中平均逃避潜伏期明显缩短,空间探索实验中第Ⅲ象限活动时间明显延长、穿越站台次数明显增多;海马细胞凋亡率明显降低;海马CA1区GFAP免疫反应阳性细胞明显减少,ChAT免疫反应阳性细胞明显增多,NFT明显减少;海马Tau-Ser396磷酸化水平明显降低;差异均有统计学意义(P<0.05). 结论 (1)耳肾、脑穴位针刺和NGF联合应用能明显改善拟AD大鼠学习记忆能力,且比单用耳针的效果更好;(2)其机制可能与减少脑细胞凋亡、减少星形胶质细胞的异常活化与增生、改善中枢胆碱能系统功能,以及抑制Tau蛋白的异常磷酸化有关.%Objective To investigate the effect of combined auricular needling and nerve growth factor (NGF) treatment on leaming and memory abilities of Alzheimer' s disease (AD) model rats,as well as their possible mechanisms.Methods Forty male SD rats were randomly assigned into four groups:normal control group,AD model group,auricular needling group,and combined

  7. Dermatoses provocadas por plantas (fitodermatoses Dermatosis due to plants (phytodermatosis

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    Vitor Manoel Silva dos Reis

    2010-08-01

    Full Text Available As dermatoses causadas por plantas são relativamente comuns no nosso meio e podem ocorrer por diversos mecanismos patogênicos. São descritas dermatoses por trauma físico, por ação farmacológica, mediadas por IgE, por irritação, por ação conjunta da luz e por sensibilização. Também são descritas na introdução desta revisão as pseudofitodermatoses causadas por elementos veiculados pelas plantas e, por isso, aparentemente causadas pelas plantas.Dermatosis caused by plants is relatively common and may occur by various pathogenic mechanisms. Dermatitis due to physical trauma, pharmacological action, irritation, sensitization, mediated by IgE and induced by light are described. Pseudophytodermatosis caused by plant-delivered elements is also described in the introduction to this work.

  8. 耳穴按压配合芳香疗法对大肠癌手术患者应激反应的影响%The effect of auricular-plaster therapy combined with aromatherapy on stress responses in patients receiving colorectal surgery

    Institute of Scientific and Technical Information of China (English)

    王晨霞; 王仲兰; 庄桂学; 金昌德

    2013-01-01

    目的 评价耳穴按压配合芳香疗法对缓解大肠癌手术患者应激反应的效果.方法 将135例大肠癌手术患者分为A组33例(耳穴按压配合芳香疗法)、B组33例(耳穴按压)、C组34例(芳香疗法)、D组35例(空白对照).采用焦虑自评量表(SAS)对4组患者不同时间点的焦虑水平进行测试;记录4组患者不同时间点的心率和血压.结果 4组不同测量时间及组间的焦虑评分、血压、心率比较,差异均有统计学意义(P<0.01).干预后A组焦虑评分、血压、心率低于B、C、D组,差异均有统计学意义(P<0.05).干预后B组和C组焦虑评分、血压、心率低于D组,差异有统计学意义(P<0.05).干预后B组焦虑评分、血压、心率与C组比较,差异无统计学意义(P>0.05).结论 耳穴按压配合芳香疗法能有效减轻大肠癌手术患者的焦虑,稳定血压和心率,且效果优于单独采用耳穴按压或芳香疗法.%Objective To evaluate the effect of auricular-plaster therapy combined with aromatherapy on stress responses in patients receiving colorectal surgery.Methods Totally 135 patients receiving colorectal surgery were randomly divided into group A(auricular-plaster therapy combined with aromatherapy),group B(auricular-plaster therapy),group C (aromatherapy) and group D(blank).The patients' anxiety was assessed by Self-Rating Anxiety Scale(SAS).Moreover,the patients' heart rate(HR) and blood pressure(BP) were recorded at different time.Results A group main effect(P<0.01),time main effect(P<0.01) and interaction effect between time and group was found(P<0.01).After intervention,the patients' anxiety,BP and HR in group A were significantly lower than group B,C and D(P<0.05); the patients' anxiety,BP and HR in group B and group C were significantly lower than group D(P<0.05).Conclusion Auricular-plaster therapy combined with aromatherapy can effectively alleviate anxiety and stabilize BP and HR in patients with colorectal

  9. Effect of auricular-plaster therapy combined with aromatherapy on anxiety and quality of life in patients with colorectal surgery%耳穴按压配合芳香疗法对大肠癌手术患者焦虑和生活质量的影响

    Institute of Scientific and Technical Information of China (English)

    王晨霞; 金昌德; 王彦鑫; 张萌

    2013-01-01

    Objective To explore the effect of auricular-plaster therapy combined with aromatherapy on anxiety and quality of life in patients with colorectal surgery.Methods A total of 135 patients with colorectal surgery were randomly divided into group A (auricular-plaster therapy combined with aromatherapy),group B(auricular-plaster therapy),group C (aromatherapy),group D(blank).Anxiety and life quality levels of four groups were determined by using self-rating anxiety scale(SAS),quality of life instruments for cancer patients (QLICP-CR)and were compared between four groups before and after intervention.Results The SAS and QLICP-CR scores of group A were lower than those of group B,group C and group D after intervention.The SAS and QLICP-CR scores of group B and group C were lower than that of group D after intervention.There were no statistical significant differences in SAS and QLICP-CR scores between group B and group C after intervention.Conclusions Auricular-plaster therapy combined with aromatherapy can effectively alleviate anxiety of patients with colorectal surgery and improve their quality of life,and the effect is better than that of auricular-plaster therapy and aromatherapy.%目的 评价耳穴按压配合芳香疗法对大肠癌手术患者焦虑和生活质量的影响.方法 将135例大肠癌手术患者随机分为A组(耳穴按压配合芳香疗法)33例、B组(耳穴按压)33例、C组(芳香疗法)34例、D组(空白组)35例,采用焦虑自评量表(SAS)、大肠癌生活质量测定量表(QLICP-CR)对4组干预前后的焦虑和生活质量水平进行测试并比较不同方法的效果.结果 A、B、C组干预前后SAS与QLICP-CR总分比较差异均有统计学意义;A、B、C组干预后的SAS和QLICP-CR总分与D组比较差异均有统计学意义;A组干预后SAS和QLICP-CR总分与B、C组比较,比较差异均有统计学意义;C组干预后SAS和QLICP-CR总分与B组比较差异无统计学意义.结论 耳穴按压配合芳香疗

  10. Control de la conducta inducida por programa por sus consecuencias ambientales

    OpenAIRE

    Ardoy Cuadros, Juan

    2008-01-01

    La presente Tesis Doctoral se ha desarrollado dentro de una de las líneas de investigación desarrollada por el Departamento de Psicología Básica I de la UNED y cuyo objetivo prioritario es el estudio de las características de la conducta inducida por programa, así como el control ambiental y farmacológico de la misma. El objetivo de esta investigación, en concreto, es determinar los factores implicados en la aparición de la polidipsia inducida por programa en ratas, así como en su mantenimi...

  11. Responsabilidad penal del empleador por delitos cometidos en la empresa por sus subordinados

    Directory of Open Access Journals (Sweden)

    Walter Jose Saavedra Troncoso

    2013-07-01

    Full Text Available En este trabajo se realiza un estudio sobre la responsabilidad penal del empresario por los actos al margen de la ley que cometen sus subordinados. Se busca aclarar si el empresario debe responder penalmente cuando el delito es cometido por un subordinado en ejercicio de sus funciones o cuando este actúa a nombre de la empresa ya sea valiéndose de la información que manejan, del grado de responsabilidad o de la confianza. Por esta razón concentraremos nuestra atención en analizar la responsabilidad penal por la omisión de controles del empresario hacia el subordinado, exponiendo la problemática que se deriva de la posición de garante del primero en las operaciones empresariales.

  12. DIATERMIA POR ONDAS CURTAS: ANÁLISE DA TEMPERATURA CORPORAL SUPERFICIAL POR TERMOGRAFIA

    OpenAIRE

    Sergio Fernando Zavarize; Anderson Martelli; Samara Aparecida Machado; Estela Maria Correia Sant’Ana

    2014-01-01

    Introdução: Poucos estudos relacionam os efeitos da diatermia por ondas curtas (DOC) e a área de aquecimento promovido por sua aplicação. Objetivo: O objetivo do trabalho foi avaliar o comportamento da temperatura superficial corporal antes e após a aplicação de DOC por meio da termografia cutânea. Materiais e métodos: A análise da temperatura corporal no local da aplicação foi realizada através da captura da imagem por meio de câmera termográfica após quinze minutos de repouso do...

  13. Responsabilidad por violación de la buena fe en la sociedad por acciones simplificada

    Directory of Open Access Journals (Sweden)

    Nicolás Polanía Tello

    2012-12-01

    Full Text Available La sociedad por acciones simplificada –SAS–, como los demás esquemas societarios, se funda en y está informada por el principio de la buena fe. Pero a diferencia de los otros modelos, la SAS tiene concreciones particulares de la buena fe que permiten un amparo más efectivo y eficiente de los derechos de los socios y de los terceros, en la medida en que instituciones como el fraude a la ley, el perjuicio injusto a terceros, el abuso del derecho y el administrador de hecho, todos estructurados a partir de violaciones a la buena fe, permiten tramitar los eventos de responsabilidad por ilícitos atípicos y llegar incluso a desestimar por ello el atributo de la limitación de responsabilidad.

  14. Muestreo por conglomerados en encuestas poblacionales

    OpenAIRE

    Zapata-Ossa, Helmer de Jesús; Angela M Cubides-Munévar; María C. López; Pinzón-Gómez, Elisa M.; Filigrana-Villegas, Paola A.; Cassiani-Miranda, Carlos A.

    2012-01-01

    Objetivo Describir la técnica estadística del muestreo por conglomerados en encuestas de salud poblacionales. Métodos Se describen los aspectos más importantes de cada uno de los pasos metodológicos   haciendo énfasis en los fundamentos del Muestreo por Conglomerados. Éste se aplicó sobre una población  de aproximadamente 100 000 habitantes de la comuna 18 de Cali. La muestra abarcó 30 manzanas y se encuestaron 3 026 personas. La información se recolectó usando el Sistema de Información de ba...

  15. Tomate industrial con riego por cinta

    OpenAIRE

    Adán Fimbres-Fontes

    2004-01-01

    La región agrícola de Caborca cuenta con una superficie de 40 000 ha, las cuales se riegan con agua proveniente de aproximadamente 700 pozos. El abatimiento del manto acuífero es, en promedio, de 0.82 m año-1 y, en 25 años, ha sido de 20.50 m, medidos al nivel estático. El agua es uno de los factores más importantes en la producción de cualquier cultivo en la región. El objetivo del presente trabajo fue optimizar la cantidad de agua por aplicar al tomate industrial cultivado con riego por cin...

  16. Conservación por calor

    OpenAIRE

    Cobos García, Angel; Díaz Rubio, Olga

    2011-01-01

    Esta unidade didáctica denominada Conservación por calor forma parte da materia «Tecnoloxía do procesado de alimentos» que se impartirá no primeiro semestre do 2º curso do Grao en Nutrición Humana e Dietética. A materia estrutúrase en diferentes unidades didácticas, tratando cada unha delas as diferentes tecnoloxías de procesado dos alimentos, tanto de conservación coma de transformación. A presente unidade didáctica aborda a conservación dos alimentos por calor. Este método permite destruír ...

  17. Celulitis por cuerpo extraño

    Directory of Open Access Journals (Sweden)

    Miguel B. Carrasco Guzmán

    2016-01-01

    Full Text Available Las infecciones de la piel y el tejido celular subcutáneo surgen como un grupo importante de afecciones con una alta morbilidad en edades pediátricas, generalmente relacionada con traumatismo y cuerpos extraños. Se presenta el caso de una escolar femenina de 6 años de edad, con síntomas y signos clínicos que sugieren celulitis en el muslo derecho,  por su evolución tórpida se le realizó el estudio ultrasonográfico que confirmó el diagnóstico etiológico de una celulitis secundaria a un traumatismo, provocada por la introducción de un gran cuerpo extraño, que pasó inadvertido para a familia de la menor.

  18. sobrevida de ratas intoxicadas por paraquat

    Directory of Open Access Journals (Sweden)

    Y. Aular

    2005-01-01

    Full Text Available La vitamina C (VC y la trimetazidina (TMZ como antioxidantes y la posible acción intiinflamatoria de esta última podrían ser de utilidad en la intoxicación por paraquat. Por tal razón se decidió evaluar el efecto de esta asociación en los niveles de VC, peso y sobrevida de ratas intoxicadas por paraquat, para ello se diseñó un estudio con 56 ratas divididas en 8 grupos: A (control negativo; B (control positivo, recibieron 11 mg/Kg. de paraquat IP; C (pre tratadas con 28.5mg/Kg. VC oral; D (tratadas con 28.5mg/Kg. VC post intoxicación; E (pre tratadas con 5mg/Kg. TMZ oral; F (tratadas con 5mg/Kg. TMZ post intoxicación; G (pre tratadas con VC- TMZ; H (tratadas con VC- TMZ post intoxicación. Se determinaron niveles de VC, cambios de peso y sobrevida en los grupos experimentales durante 31 días. Los resultados mostraron el día 24 de experimentación: disminución de los niveles de VC en el grupo E (p<0.05 y aumento en el grupo G (p< 0.001, sobrevida de 62.5% (grupo G, 50% (grupos E y H y 25% (grupos C y D. Se concluye que la asociación VC- TMZ aumentó la sobrevida de ratas intoxicadas por paraquat

  19. Intoxicación por drogas

    Directory of Open Access Journals (Sweden)

    I. Gainza

    2003-01-01

    Full Text Available El consumo de drogas ilegales en nuestro país ha experimentado un notable cambio en los últimos años, relegando a la heroína e incorporando la cocaína, los derivados anfetamínicos como el "éxtasis" (MDMA, el "éxtasis líquido" (GHB y, en menor medida, la ketamina. Se lleva a cabo una revisión de la intoxicación aguda por opiáceos y de su tratamiento en los servicios de urgencias, teniendo en cuenta el descenso progresivo de los casos que se presentan con el advenimiento de nuevas formas de administración, así como la presencia de nuevas drogas adictivas que han dado lugar a un desplazamiento en los hábitos de consumo. Se expone la intoxicación por cocaína haciendo referencia a la clínica, el diagnóstico y el tratamiento. Se realiza una revisión sobre el cannabis y sus derivados, la historia de su consumo y preparaciones utilizadas, los efectos que producen en los distintos sistemas del organismo y sus principales mecanismos de acción. Por último se comentan los efectos del LSD y de las setas alucinógenas.

  20. Intoxicación aguda por plaguicidas

    Directory of Open Access Journals (Sweden)

    Durán-Nah Jaime Jesús

    2000-01-01

    Full Text Available OBJETIVO: Describir la epidemiología de la intoxicación aguda por plaguicidas (IAP en el Hospital General O'Horán de Mérida, Yucatán, México. MATERIAL Y MÉTODOS: Se revisaron los expedientes de 33 pacientes superscript three 13 años, tratados en una unidad de cuidados intensivos (UCI, entre 1994 y 1998. Se recopilaron variables demográficas y clínicas relevantes, y se aplicó estadística descriptiva. RESULTADOS: En la población estudiada predominó el sexo masculino (82% del medio rural (70%, y la edad media fue de 34 ± 15.8 años. El intento de suicidio fue causa frecuente de IAP (79%, y en 33% de los casos la intoxicación se produjo por la utilización de organofosforados. La mortalidad fue de 12%. CONCLUSIONES: La IAP fue baja entre los sujetos del medio rural, por lo que los resultados de este estudio parecen no reflejar la realidad del problema. Es importante añadir que los plaguicidas son utilizados con relativa frecuencia para el intento de suicidio.

  1. Leibniz damnificado por el terremoto de Lisboa

    Directory of Open Access Journals (Sweden)

    Evaristo ÁLVAREZ MUÑOZ

    2009-11-01

    Full Text Available RESUMEN: En las páginas que siguen se argumenta que al filósofo alemán Gottfried Wilhelm Leibniz —fallecido en Hannover en 1716— o, al menos, a su obra Teodicea, cabría contarlos, echadas las cuentas de la manera que se verá, entre las víctimas del terremoto de Lisboa de 1755. Asimismo se subraya la persistencia del pensamiento de Leibniz en las respuestas dadas por los filósofos del siglo XVIII al trágico suceso. Se estudian las reacciones de Voltaire, de Rousseau y de Kant ante los estragos provocados por el seísmo y se concluye que las manifestaciones de los dos primeros ya habían sido previstas en Teodicea e, incluso, la vía científica pretendida por Kant había sido abierta en Protogaea.ABSTRACT: It is argued here that German philosopher Gottfried Wilhelm Leibniz, passed away in 1716, and, specially, that his work Teodicea, could be considered amongst the victims of the Lisbon earthquake of 1755. The persistence of the Leibniz’s thought in the answers given by the philosophers of the 18th Century to the tragic event is also emphasized. Voltaire and Rousseau’s reactions to the damage caused by the earthquake had been anticipated in Teodicea and the scientific way followed by Kant had been initiated in Protogaea.

  2. Por un humor ético

    Directory of Open Access Journals (Sweden)

    Victor Paramo Valero

    2016-04-01

    Full Text Available Ética del humor es una obra original, abundantemente documentada, de contenido científico y filosófico, que aborda un problema de gran importancia en los actuales estudios de éticas aplicadas. La ética del humor es una nueva ética aplicada que pretende comprender el fenómeno del humor a la luz de sus implicaciones éticas. Como señala el autor, Juan Carlos Siurana, reputado experto en el ámbito de la filosofía práctica, el interés por el humor es un interés por la ética. En la obra no presenta una nueva teoría filosófica del humor –las cuales se han venido sucediendo, al menos, desde los Diálogos de Platón–, sino una nueva teoría ética, que toma al humor como objeto principal de análisis. Por tanto, la finalidad es realizar una aportación dentro del ámbito de la ética. Para ello se nutre de distintos estudios psicológicos, biológicos, fisiológicos y neurológicos sobre el humor, así como de clásicas obras de filosofía que han abordado esta cuestión.

  3. Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System.

    Science.gov (United States)

    Gorasia, Dhana G; Veith, Paul D; Hanssen, Eric G; Glew, Michelle D; Sato, Keiko; Yukitake, Hideharu; Nakayama, Koji; Reynolds, Eric C

    2016-08-01

    The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown. In this study, we purified PorK and PorN complexes from P. gingivalis and using electron microscopy we have shown that PorN and the PorK lipoprotein interact to form a 50 nm diameter ring-shaped structure containing approximately 32-36 subunits of each protein. The formation of these rings was dependent on both PorK and PorN, but was independent of PorL, PorM and PorP. PorL and PorM were found to form a separate stable complex. PorK and PorN were protected from proteinase K cleavage when present in undisrupted cells, but were rapidly degraded when the cells were lysed, which together with bioinformatic analyses suggests that these proteins are exposed in the periplasm and anchored to the outer membrane via the PorK lipid. Chemical cross-linking and mass spectrometry analyses confirmed the interaction between PorK and PorN and further revealed that they interact with the PG0189 outer membrane protein. Furthermore, we established that PorN was required for the stable expression of PorK, PorL and PorM. Collectively, these results suggest that the ring-shaped PorK/N complex may form part of the secretion channel of the T9SS. This is the first report showing the structural organization of any T9SS component.

  4. Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System.

    Science.gov (United States)

    Gorasia, Dhana G; Veith, Paul D; Hanssen, Eric G; Glew, Michelle D; Sato, Keiko; Yukitake, Hideharu; Nakayama, Koji; Reynolds, Eric C

    2016-08-01

    The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown. In this study, we purified PorK and PorN complexes from P. gingivalis and using electron microscopy we have shown that PorN and the PorK lipoprotein interact to form a 50 nm diameter ring-shaped structure containing approximately 32-36 subunits of each protein. The formation of these rings was dependent on both PorK and PorN, but was independent of PorL, PorM and PorP. PorL and PorM were found to form a separate stable complex. PorK and PorN were protected from proteinase K cleavage when present in undisrupted cells, but were rapidly degraded when the cells were lysed, which together with bioinformatic analyses suggests that these proteins are exposed in the periplasm and anchored to the outer membrane via the PorK lipid. Chemical cross-linking and mass spectrometry analyses confirmed the interaction between PorK and PorN and further revealed that they interact with the PG0189 outer membrane protein. Furthermore, we established that PorN was required for the stable expression of PorK, PorL and PorM. Collectively, these results suggest that the ring-shaped PorK/N complex may form part of the secretion channel of the T9SS. This is the first report showing the structural organization of any T9SS component. PMID:27509186

  5. 耳针对阿尔茨海默病大鼠记忆能力及ChAT和GFAP表达的影响%Effects of auricular acupuncture on the memory and the expression of ChAT and GFAP in model rats with Alzheimer's disease

    Institute of Scientific and Technical Information of China (English)

    苗婷; 蒋天盛; 董宇华; 蒋乃昌

    2009-01-01

    Objective To observe the effects of auricular acupuncture on the learning and memory abilities of model rats with Alzheimer's disease (AD) , and investigate its mechanism. Methods Thirty SD rats were randomly divided into a control group, a model group and an auricular acupuncture group, 10 rats in each group. The model rats with AD were established by multiple injections with Okadaic Acid into the CA1 region of hippocampus. In the control group, the same quantity injection with Dimethyl Sulfoxide (DMSO) was applied on experimental rats. The auricular acupoints of "Nao" (brain) and "Shen" (kidney) were used for treating in the auricular acupuncture group, in contrast, the auricular region were not treated in the model and the control groups. The learning and memory capabilities of the rats were assessed with Morris Water Maze behavioral test, and the expressions of choline acetyl-transferase (ChAT) and glial fibrillary acidic protein (GFAP) were examined by immunohistochemistry. Results Comparing with the model group, the treated AD rats with auricular acupuncture was showed that the average escape latency was obviously shortened in the place navigation test (P<0.01) , the movement time in plateform quadrant was obviously prolonged in the spatial probe test (P<0.05) , and the number of traversing platform obviously increased (P<0.01) after the platform was taken away. The expression of ChAT increased in the hippocampus and cortex (P<0.01, P<0.05) , but the expression of GFAP obviously decreased in the CA1 region of hippocampus (P<0.01). Conclusion Auricular acupuncture can improve the learning and memory capability of the model rats with AD. Its mechanism might be related with decreasing cholinergic neuron damage and reducing the abnormal activation and hyperplasia of astrocyte.%目的:观察耳针对阿尔茨海默病(AD)大鼠学习记忆能力的影响,并探讨其可能机制.方法:30只SD大鼠随机分为对照组、模型组、耳针组,每组10只.模型

  6. 猪耳廓及关节来源软骨细胞构建组织工程软骨的实验研究%Comparison study of tissue engineered cartilage constructed with chondrocytes derived from porcine auricular and articular cartilage

    Institute of Scientific and Technical Information of China (English)

    康宁; 刘霞; 曹谊林; 肖苒

    2014-01-01

    Objective To compare the tissue engineered cartilage constructed with chondrocytes derived from auricular and articular cartilage.Methods Chondrocytes were isolated from porcine auricular and articular cartilage,and BMSCs were obtained from bone marrow aspirate and cultured.Each kind of chondrocytes were resuspended alone or mixed with BMSCs at a ratio of 1 ∶ 1,and seeded onto PGA/PLA scaffolds to construct tissue engineered cartilage(n =4).The constructs were cultured for 8 weeks in vitro and then subcutaneously implanted into nude mice for 6 weeks.The differences between chondrocytes monoculture from articular and auricular cartilage or between each of them co-cultured with BMSCs were evaluated by gross view,measurement of thickness and wet weight,histological examinations including H&E,Safranin O,type Ⅱ collagen,and Ponceau' s & Victoria blue staining,and gene expression analysis of cartilage related genes.Results No obvious differences were found histologically among the complexes constructed in vitro 8 weeks except for few elastic fibers secreted in the auricular chondrocytes + BMSCs coculture group.Neo-cartilage is thicker in the groups of articular chondrocytes (38.1% than the group of auricular chondrocytes,P < 0.05) and articular chondrocytes + BMSCs co-culture (19.3% than the group of auricular chondrocytes + BMSCs,P < 0.05).However,after 6 weeks in vivo the elastic fibers were found positive in the complexes constructed by auricular chondrocytes,and its staining was even stronger and more homogenous in the group of auricular chondrocytes + BMSCs co-culture.The tissues generated by articular chondrocytes alone and co-cultured with BMSCs both formed the characteristic features of three-layer structure of hyaline cartilage and ossified in vivo with significant up-regulation of COL10A1 and MMP-13.To summarize,auricular chondrocytes formed the elastic cartilage while articular chondrocytes formed the hyaline cartilage during the development of

  7. 黑木耳多糖对ICR小鼠皮肤光老化的保护作用%Protective effects of Auricularia auricular polysaccharide on skin photoaging in ICR mice

    Institute of Scientific and Technical Information of China (English)

    易清玲; 曾维惠; 刘彦婷; 徐磊

    2012-01-01

    目的:探讨黑木耳多糖(Auricularia auricular polysaccharide,AAP)对ICR小鼠皮肤光老化的保护作用.方法:选取健康雌性ICR小鼠共50只,随机分成5组各10只:正常组(A)、模型对照组(B)、模型+AAP低剂量(50 mg/kg.d)灌胃组(C)、模型+AAP中剂量(100 mg/kg.d)灌胃组(D)、模型+AAP高剂量(200 mg/kg.d)灌胃组(E).长波紫外线(ultraviolet A,UVA)联合中波紫外线(ultraviolet B,UVB)照射小鼠制备皮肤光老化模型.每周一、三、五照射,第1周每次照射时间1h,以后每周依次增加1h,自第5周起为5h,直至第14周照光结束.每次照光前各治疗组小鼠给予不同浓度的AAP灌胃.实验结束后取小鼠背部皮肤用测试盒测定超氧化物歧化酶(superoxide dismutase,S0D)及谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-PX)活力、丙二醛(malondialdehyde,MDA)含量;组织切片HE染色观察皮肤结构改变.结果:与正常组比较,模型对照组皮肤组织中S0D、GSH-PX活力显著降低(P<0.05),MDA含量显著增高(P<0.05);与模型组对照组比较,AAP各灌胃组S0D、GSH-PX活力显著升高(P<0.05),MDA含量显著降低(P<0.05).模型对照组皮肤出现皮屑、褐黄、粗糙肥厚、深皱纹、缺乏弹性等光老化特征,组织切片呈现光老化改变.AAP各治疗组皮肤外观及组织学特点均较模型对照组明显改善.结论:AAP能有效提高小鼠抗氧化能力,对小鼠皮肤光老化有保护作用.%Objective To study the protective effects of Auricularia auricular polysaccharide (AAP)on photoaged ICR mice skin. Methods Fifty healthy female ICR mice were divided into five groups (n = 10) randomly: normal group(A), model control group (B),at dose of 50 mg/kg.d group (C), at dose of 100 mg/kg.d group (D), at dose of 200 mg/kg.d group (E). To establish skin photoaging mice models by irradiated UVA and UVB three times weekly (Monday, Wednesday and Friday).ln the first week the time of UV exposure was 1 hour each time, then

  8. Automated breast volume system on costal cartilage before autogenous auricular reconstruction%自体肋软骨耳廓成形术术前肋软骨自动乳腺全容积成像系统显像

    Institute of Scientific and Technical Information of China (English)

    俞理; 申锷; 胡兵

    2012-01-01

    To analyze the automated breast volume system (ABVS) ultrasonic appearances of the right 6th to 9th costal cartilages and the synchondrosis of 6th—7th and 7th—8th costal cartilages on coronary planar images, in order to evaluate its value in preoperative assessment of autogenous auricular reconstruction. Methods Forty volunteers underwent ABVS examination on their right chests. The ultrasonic features of costal cartilages and the synchondrosis on the coronary planar images were observed. The length, width and thickness of 6th to 9th costal cartilages were measured, as well as the synchondrosis of 6th—7th and 7th—8th costal cartilages. The calcifications on the 6th to 9th costal cartilages were observed, and the difference of the display rate between the two genders was analyzed* Results The inner details and the morphology features could be clearly displayed on ABVS. The coronary planar image could display 2—4 synchondrosis and the neighboring costal cartilages. The display rate of the synchondrosis of 6th—7th costal cartilage was 100% , as well as the synchondrosis of 7th—8th costal cartilage. The length and width of 6th to 9th costal cartilages in the male were longer than those in the female, as well as the synchondrosis of 6th—7th and 7th—8th costal cartilages (P0. 05), neither was the calcifications display rate of the 6th to 9th costal cartilages (x2 = 1.230, P>0. 05). Conclusion ABVS is a valuable new method on costal cartilages and the synchondrosis imaging, which can be applied in the preoperative assessment of autogenous auricular reconstruction practicably and effectively.%目的 分析自动乳腺全容积成像系统(ABVS)在成人右侧第6~9肋软骨以及6、7及7、8肋软骨联合部位的成像特点,评估其在自体肋软骨耳廓成形术术前肋软骨影像学评估中的价值.方法 对40名志愿者右侧胸廓行超声AB-VS检查,观察右胸肋软骨及肋软骨联合部位的冠状面超

  9. Therapeutic Observation of Auricular Point Sticking plus Moxibustion in Preventing Spleen-stomach Disharmony Due to Intravenous Analgesia Pump%耳穴贴压配合艾灸预防静脉镇痛泵所致脾胃失和证疗效观察

    Institute of Scientific and Technical Information of China (English)

    孙艳; 黄文红

    2015-01-01

    目的:观察耳穴贴压配合足三里艾灸预防静脉镇痛泵所致脾胃失和证的临床疗效。方法将120例留置静脉镇痛泵的手术患者随机分为治疗组和对照组,每组60例。对照组术后采用给予半卧位、协助床上翻身和早期起床活动指导等常规术后护理。治疗组在对照组基础上给予耳穴贴压配合足三里艾灸治疗。观察两组患者术后恶心、呕吐及腹胀的发生率。结果治疗组恶心、呕吐及腹胀发生率为11.7%,对照组为33.3%,两组比较差异具有统计学意义(P<0.05)。结论耳穴贴压配合足三里艾灸能有效预防静脉镇痛泵所致的脾胃失和证,能减轻患者痛苦,并减少并发症。%Objective To observe the clinical efficacy of auricular point sticking plus moxibustion at Zusanli (ST 36) in preventing spleen-stomach disharmony due to intravenous analgesia pump.Method Totally 120 post-operation patients with intravenous analgesia pump were randomized into a treatment group and a control group, 60 in each group. Patients in the control group were asked to take a semireclining position, and to turn over the body and do morning exercise under assistance. In addition to the intervention given to the control group, the treatment group received auricular point sticking plus moxibustion at Zusanli (ST 36). The occurrence rate of post-operation nausea, vomiting and abdominal bloating was observed.Result The occurrence rate of nausea, vomiting and abdominal bloating was 11.7% in the treatment group, versus 33.3% in the control group, and the difference was statistically significant (P<0.05).Conclusion Auricular point sticking plus moxibustion at Zusanli (ST 36) is effective in preventing spleen-stomach disharmony due to intravenous analgesia pump, and can reduce pain and complications.

  10. 脑功能治疗仪联合耳穴压豆治疗老年失眠患者的临床观察%Clinical observation on treating insomnia in elderly patients by brain function therapeutic apparatus combined with auricular oppression therapy

    Institute of Scientific and Technical Information of China (English)

    卢慧清

    2014-01-01

    Objective:Observing the effect of brain function therapeutic apparatus combined with auricular oppression therapy on treating insomnia in elderly patients, thus confirming that the method can reduce the dose of sleeping pills, reduce medicines side effects, and further improve the quality of sleep in patients. Methods:Post-infarction patients with insomnia were given brain function therapeutic apparatus treatment, 2 times a day, and 10 days for a course of treatment, plus auricular oppression therapy, 10 days for a course of treatment, after the course, the effect was observed. Results:11 cases were cured, markedly effective in 14 cases, effective in 14 cases, 5 cases ineffective, and the total efficiency of 90.0%. Conclusion:Brain function therapeutic apparatus combined with auricular oppression therapy is effective on treating insomnia in elderly patients.%目的:观察脑功能治疗仪联合耳穴压豆治疗脑梗塞后失眠疗效,从而证实该方法可减少卒中老年失眠患者口服安眠药剂量,降低药物毒副作用,进一步改善患者的睡眠质量。方法:对脑梗塞后失眠患者采用脑功能治疗仪治疗,2次/d,10d为1个疗程。配合耳穴治疗,10d为1个疗程,病程后观察疗效。结果:治愈11例,显效14例,有效20例,无效5例。总有效率90.0%。结论:脑功能治疗仪配合耳穴压豆治疗可以有效提高老年失眠患者的疗效。

  11. Effect of auricular needle on angiotensin converting enzyme and endothelin content of patients with hyperten-sion and vertigo%耳针对高血压眩晕患者血管紧张素转化酶和内皮素含量的影响

    Institute of Scientific and Technical Information of China (English)

    舒遵华

    2016-01-01

    Objective:To explore the effect of Auricular needle on angiotensin converting enzyme(ACE)and endothelin content(ET) of patients with hypertension and vertigo.Methods:60 patients with hypertension were selected.They were divided into the two groups on average.The control group was treated with perindopril treatment,while the treatment group was treated by auricular needle on the basis of the control group.We observed the correlation index.Results:After treatment,the blood pressure,vertigo symptoms score,ET,ACE levels of the two groups were significantly different than before the treatment;the vertigo symptoms score, ET,ACE levels of the treatment group were better than the control group.Conclusion:On the basis of oral administration of perindopril,auricular needle therapy failed to significantly improve the antihypertensive efficacy,but it can significantly improve the symptoms of patients with vertigo,and the effect is better than simply taking perindopril.%目的:探讨耳针治疗高血压眩晕患者的疗效及其对血管紧张素转化酶(ACE)和内皮素(ET)含量的影响。方法:收治高血压患者60例,平分为两组,对照组口服培哚普利治疗,治疗组在此基础上采用耳针治疗,观察相关指标。结果:两组治疗后血压、眩晕症状评分、ET、ACE水平与治疗前比较均有明显差异,治疗组治疗后眩晕症状评分、ET、ACE水平优于对照组。结论:在口服培哚普利的基础上,耳针疗法未能显著提高降压疗效,但能够显著改善患者眩晕症状,疗效明显优于单纯服用培哚普利。

  12. The effect of diode laser treatment for hair removal of post-auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap%半导体激光治疗耳后延迟皮瓣加自体肋软骨立体支架法耳再造术后耳廓多毛疗效观察

    Institute of Scientific and Technical Information of China (English)

    吴子涵; 李高峰; 谭军; 丁卫; 张帆

    2015-01-01

    目的:观察半导体激光对耳后延迟皮瓣加自体肋软骨立体支架法耳再造术后耳廓多毛的治疗效果。方法:使用美国科医人(Lumenis)公司Lightsheer 800 nm半导体激光进行治疗。耳后延迟皮瓣加自体肋软骨立体支架法耳再造术III期手术后1~3个月开始行激光脱毛治疗。结果:19例患者通过1~7次的脱毛治疗,均取得了良好的效果,治疗期间无严重的不良反应。结论:Lightsheer 800 nm半导体激光对耳后延迟皮瓣加自体肋软骨立体支架法耳再造术后耳廓多毛的治疗效果良好,使再造耳的形态更美观。%Objective To observe the effect of diode laser treatment for hair removal of post-auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap. Methods To use Lightsheer,800nm diode laser to perform the treatment.Hair removal treatment was performed after the third phase operation of auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap. Results All of 19 patients got good result after hair removal treatment after 1 to 7 times.No serious complications occur during treatment. Conclusion Lightsheer,800nm diode laser is a safe and effective treatment of hair removal after auricular reconstruction with autologous costal cartilage grafts and delaying postauricular skin flap. That makes the shape of reconstructive ear preferable.

  13. Comparison of Instant Antihypertensive Effect of Auricular Points Pressing with Seeds on Different Syndromes of Essential Hypertension%耳穴压豆疗法对不同证型原发性高血压即时降压疗效比较

    Institute of Scientific and Technical Information of China (English)

    魏思宁; 王鸿庆; 郭栋

    2016-01-01

    目的:观察耳穴压豆疗法对多证型原发性高血压即时降压效果比较。方法:95例原发性高血压患者分为肝火亢盛型组、阴虚阳亢型组、痰湿壅盛型组、阴阳两虚型组,并运用耳穴压豆疗法,观察治疗后各证型高血压患者即时血压下降情况。结果:各组血压均有不同程度下降,其中肝火亢盛型组、阴虚阳亢型组血压下降幅度较痰湿壅盛型组、阴阳两虚型组明显。结论:耳穴压豆疗法对肝火亢盛型、阴虚阳亢型高血压病即时降压治疗效果较好。%Objective:To observe the instant antihypertensive effect of auricular points pressing with seeds on different syndromes of essential hypertension. Methods:A total of 95 patients with essential hypertension were divided into four groups of four different syndromes:liver-fire excess syndrome,Yin deficiency and Yang ex-cess syndrome,accumulation of phlegm and dampness syndrome,Yin and Yang deficiency syndrome. All the patients were treated with auricular points pressing with seeds. Then compare decrease of blood pressure of the four different syndromes. Results:The blood pressure of the four syndromes decreased to different extent. The blood presure of liver-fire excess syndrome and Yin deficiency and Yang excess syndrome decreased more obviously than those of the accumulation of phlegm and dampness syndrome and Yin and Yang defi-ciency syndrome. Conclusion:Auricular points pressing with seeds has better instant antihypertensive effect on liver-fire excess syndrome and Yin deficiency and Yang excess syndrome.

  14. Cefaleia por uso excessivo de medicamentos

    Directory of Open Access Journals (Sweden)

    Ariane Maria Fonseca MIRANDA

    2015-01-01

    Full Text Available Uma variante da cefaleia crônica diária, a cefaleia por uso excessivo de medicamentos é uma manifestação clínica de frequência ≥ 15 dias por mês, durante 3 meses. Possui um diagnóstico deficiente e um tratamento dividido em etapas, sendo a desintoxicação, a etapa de fundamental importância. Este artigo apresenta uma revisão sobre o tema, contribuindo para o esclarecimento das principais manifestações clínicas, principais teorias envolvendo sua fisiopatologia e a terapêutica farmacológica empregada. A metodologia utilizada foi uma revisão de publicações europeias e americanas, no período de 2001 a 2013, nos idiomas português, inglês e espanhol. Todos os medicamentos utilizados no tratamento sintomático das cefaleias são capazes de cronificar uma cefaleia preexistente, desde que sejam utilizados excessivamente, de forma regular e continuada. A suspensão de tais agentes terapêuticos resultará em melhoria na maioria dos pacientes, porém pode ser necessária a introdução de uma terapia de suporte de transição e/ou terapia profilática. Os tratamentos nao farmacológicos, quando associados ao farmacológico, ampliam a possibilidade de resultados satisfatórios, evitando recaídas.

  15. Bacteremias por bacilos gram-negativos

    Directory of Open Access Journals (Sweden)

    Adrelírio J. R. Gonçalves

    1969-01-01

    Full Text Available São apresentados 31 casos de bacteremia por gram-negativos, assunto que vem merecendo muita atenção dos pesquisadores nos últimos anos. Os organismos etiológicos mais importantes que apareceram em igualdade de freqüência foram Escherichia coli e Klebsiella-Aerobacter, sendo responsáveis por 58% do total das infecções, seguidos por Pseudomonas. A porta de entrada mais freqüente foi o trato urinário em 61,3% dos casos. A infecção foi mais comum no sexo masculino e a faixa etária de 50 a 60 anos predominou. O uso prévio de antibióticos foi um fator predisponente muito importante, seguido pelo uso de esteróides e citostáticos. As principais doenças predisponentes foram diabetes mellitus e neoplasias malignas. Os principais fatores precipitantes foram a manipulação do aparelho urinário, com infecção prévia ou desencadeada, cirurgia do aparelho digestivo, uronatia obstrutiva e obstrução biliar. As principais manifestações clínicas foram a presença de febre, calafrios e hipotensão arterial. A complicação mais freqüente foi o choque bacteriano que incidiu em 58% dos casos, aproximadamente três vêzes aquela relatada na literatura. As outras foram a insuficiência renal aguda, superinfecção e infecção pulmonar metastática. Considerações terapêuticas gerais e esquemas de antibióticos são propostos para estes casos. A mortalidade da bacteremia simples foi de 30,7% e quando associada ao choque elevou-se para 72,2% . As infecções por Pseudomonas foram 100% fatais.

  16. Travesía por mares piratas

    OpenAIRE

    Herrera, Elixabete

    2015-01-01

    Se analiza el viaje del buque quimiquero Mar María por zonas de alto riesgo de piratería, basada en la experiencia de supervivientes a ataques piratas, y se hace un resumen de la regulación legal de la piratería. Se explicitan la valoración de riesgos, las medidas de protección y el plan de contingencia antipirata. La construcción de una ciudadela es otro de los temas que se tratan, así como la manera de identificar a piratas.

  17. Leibniz damnificado por el terremoto de Lisboa

    OpenAIRE

    Evaristo ÁLVAREZ MUÑOZ

    2005-01-01

    RESUMEN: En las páginas que siguen se argumenta que al filósofo alemán Gottfried Wilhelm Leibniz —fallecido en Hannover en 1716— o, al menos, a su obra Teodicea, cabría contarlos, echadas las cuentas de la manera que se verá, entre las víctimas del terremoto de Lisboa de 1755. Asimismo se subraya la persistencia del pensamiento de Leibniz en las respuestas dadas por los filósofos del siglo XVIII al trágico suceso. Se estudian las reacciones de Voltaire, de Rousseau y de Kant ante los estragos...

  18. Estrategias de crecimiento empresarial aplicadas por hipermercados

    OpenAIRE

    Miraidy Leal Morantes; Yilian Cefalá Chirinos

    2003-01-01

    El presente estudio tiene como objetivo caracterizar las estrategias de crecimiento empresarial, representadas por alianzas y adquisiciones, que han sido aplicadas en el sector de distribución de bienes de consumo masivo, específicamente en los hipermercados ubicados en Maracaibo, Estado Zulia, como manera de responder al entorno competitivo y cambiante en el cual se desenvuelven. La investigación se desarrolló a través de un estudio de carácter descriptivo; para la recolección ...

  19. Neumonía por Stenotrophomonas maltophilia

    OpenAIRE

    Verny Huertas-Franco; María Isabel Lacayo-Pallais

    2014-01-01

    La Stenotrophomonas maltophilia es un bacilo gram negativo ambiental emergente que ha venido posicionándose entre el grupo de microorganismos multirresistentes como causa de infección en diversos órganos en ambiente hospitalario y en la comunidad. Se reporta este caso de insuficiencia respiratoria con neumonía severa por S. maltophilia adquirida en la comunidad en una paciente inmunocompetente que tuvo una rápida respuesta a tratamiento con trimetoprim sulfametoxazol cuando se logró identific...

  20. Los Cuentos Por Proyectos De Trabajo Global.

    OpenAIRE

    Reinaldos, María Inmaculada

    2012-01-01

    La educación infantil es importante en los primeros años del niño, ya que un aprendizaje temprano es determinante para un buen desarrollo cognitivo, motor, psicológico, intelectual, emocional, social del individuo, y para la formación de las facultades intelectuales y el desarrollo de la personalidad. La L.O.E. (2006) aboga por una enseñanza globalizada, y que abarque todas las dimensiones del niño, para que de esta forma se consiga un aprendizaje significativo. Actualmente, se apuesta ...

  1. Gestión por competencias

    OpenAIRE

    Patiño Rubiano, Benjamín

    2006-01-01

    El desarrollo de este trabajo tiene como objetivo principal comparar los modelos de gestión por competencias implementados en otras organizaciones para retroalimentarlo en la organización Schneider Electric de Colombia S.A Agencia Antioquia. Para el desarrollo del tema lo primero que se hizo fue hacer un análisis teórico, del cual se presentará una síntesis. Las competencias son la capacidad de hacer algo bien y en determinadas condiciones, su objetivo es el aprovechamiento de las cualidades ...

  2. Regulación por precios tope

    Directory of Open Access Journals (Sweden)

    Gerardo Soto Carrillo

    2009-06-01

    Full Text Available El presente trabajo describe las principales características del mecanismo de regulación por precios tope, incluyendo su ubicación dentro de las posibilidades de acción regulatoria, las críticas que se han planteado al mismo, así como los mecanismos complementarios utilizados y los riesgos involucrados en su desarrollo.---This article describes the main characteristics of the price cap regime of price regulation, including its location among other regulatory possibilities, critics received, complementary mechanisms and risks involved in its development.

  3. Neumonía por Stenotrophomonas maltophilia

    Directory of Open Access Journals (Sweden)

    Verny Huertas-Franco

    2014-03-01

    Full Text Available La Stenotrophomonas maltophilia es un bacilo gram negativo ambiental emergente que ha venido posicionándose entre el grupo de microorganismos multirresistentes como causa de infección en diversos órganos en ambiente hospitalario y en la comunidad. Se reporta este caso de insuficiencia respiratoria con neumonía severa por S. maltophilia adquirida en la comunidad en una paciente inmunocompetente que tuvo una rápida respuesta a tratamiento con trimetoprim sulfametoxazol cuando se logró identificar la bacteria.

  4. Por qué necesitamos la competencia

    OpenAIRE

    Schnappauf, Werner

    2010-01-01

    "La gran aportación de la Economía Social de Mercado es que domestica al capitalismo y lo lleva por caminos ordenados de modo que pone la tendencia humana al beneficio al servicio del bien común, conciliando el beneficio individual y el del conjunto de lasociedad", afirmó Werner Schnappauf, Director General de la Confederación Federal de la Industria Alemana (BDI), con motivo del 43 Simposio de Innsbruck del Instituto de Investigación para la Constitución Económica y la Competencia (FIW), ...

  5. Sistema de climatización por suelo radiante coalimentado por energías renovables

    OpenAIRE

    Valdivieso Sarabia, Rafael Jesús; García Chamizo, Juan Manuel; Ferrández Pastor, Francisco Javier; Flórez-Revuelta, Francisco

    2010-01-01

    Se presenta el sistema de climatización basado en suelo radiante coalimentado por fuentes de energía renovables, que es capaz de proporcionar calor o frío. Se ha modelado una instalación genérica, que ha sido particularizada e integrada en una vivienda-laboratorio de unos 54m2. El sistema está compuesto por placas termo-solares, calentador eléctrico, bomba de calor aire-agua, acumuladores, circuito de suelo radiante y fancoil. El sistema de control está basado en un autómata que integra senso...

  6. Nodulose por Metotrexato Methotrexate Induced Nodulosis

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    Fernanda Guidolin

    2005-08-01

    Full Text Available A nodulose por metotrexato (MTX é um dos efeitos colaterais pouco conhecidos do uso desse medicamento em doses baixas. Embora classicamente descrita em casos de artrite reumatóide, tem aparecido, também, em outras doenças reumáticas. Descreve-se aqui um caso de nodulose por MTX em uma paciente com artrite reumatóide soropositiva, que utilizava esse medicamento há um ano, com bom controle do processo articular. Segue-se uma breve revisão sobre o assunto.Methotrexate-induced nodulosis is a rare side effect of this drug when it is used in low doses. Although classically described in rheumatoid arthritis patients, it may also appear in other rheumatic disorders. We describe a seropositive rheumatoid arthritis patient who developed methotrexate-induced nodulosis after using this drug for a year, with good control of articular symptoms. This case presentation is followed by a brief revision on the subject.

  7. Choque séptico por ehrliquiosis

    Directory of Open Access Journals (Sweden)

    Viviana Hernández-de Mezerville

    2007-04-01

    Full Text Available La ehrliquiosis humana es una infección zoonótica transmitida por "garrapatas duras" causada por Anaplasma sp y Ehrlichia sp. Puede presentarse como un cuadro pseudogripal con fiebre, malestar general, mialgias y cefalea o hasta un choque séptico con falla multiorgánica y muerte. La mitad de los pacientes requieren atención hospitalaria en algún momento y se reporta una mortalidad de hasta el 5% secundaria a enfermedades oportunistas o a hemorragias. El diagnóstico se puede sospechar visualizando las mórulas intracitoplasmáticas en las células afectadas en frotis de sangre periférica, y se confirma con serología, con cultivos o con detección molecular. El tratamiento de elección es la doxiciclina con buena respuesta clínica. Se reporta un caso probable de ehrliquiosis humana asociado a choque séptico y falla multiorgánica tratado exitosamente en el Hospital Dr. Rafael Angel Calderón Guardia.

  8. Luchas por el control territorial en Colombia

    Directory of Open Access Journals (Sweden)

    Darío I. Restrepo

    2002-01-01

    Full Text Available La tesis central del artículo es que la concurrencia entre los impactos de la globalización, el proceso de descentralización y la crisis política debilitan gravemente el Estado-Nación, y particularmente tienden a romperse las bases mismas del centralismo polÌtico, administrativo y económico. Por otra parte, se exacerban las luchas locales por la apropiación de las riquezas materiales y el control de las instituciones. De esta manera, se acrecienta el poder de negociación política de las fuerzas locales frente al gobierno central, tanto respecto de las funciones descentralizadas como de aquellas que mantiene el Estado de manera centralizada. Neoliberales, reformadores políticos, clases políticas territoriales, nuevos movimientos sociales, narcotraficantes, guerrilleros y paramilitares se disputan abiertamente el poder local. Todos tienen una estrategia, o al menos un conjunto de intereses y prácticas respecto del proceso de descentralización, el cual en última instancia no puede ser entendido sino como el resultado de la complejidad de fuerzas que intervienen en él.

  9. Comparación entre el uso de audífonos extra e intra-auriculares en la realización de potencial vocado auditivo de tronco encefálico en caninos sanos en la Universidad Estatal Paulista, Julio de Mesquita Filho, campus Botucatu, Brasil

    OpenAIRE

    Avila Rubiano, María Angélica

    2014-01-01

    Se realizó la prueba de Potencial Evocado Auditivo de Tronco Encefálico en 10 caninos adultos, sanos, mestizos, entre uno y ocho años con audífonos extra e intra-auriculares. Se ofrecieron estímulos en forma de clic, de polaridad alternante, con 0,2ms de duración, intensidad de 85dB y frecuencia de 13Hz. Se calcularon las medias y la desviación estándar de las latencias y amplitudes de las ondas I, II, III y V, de los intervalos I-III, III-V y I-V y de la relación V/I. No se encontraron difer...

  10. The Influence of Auricular Seed-Embedding Therapy over the Psychological Health of Family Members with MR Children%耳穴埋籽对精神发育迟缓患儿家属心理健康水平的影响

    Institute of Scientific and Technical Information of China (English)

    石娜

    2015-01-01

    目的:探讨耳穴埋籽对精神发育迟缓患儿家长的心理健康水平的影响。方法:将精神发育迟缓患儿家长105名随机分为2组,分别采用症状自评量表测量其心理健康水平,并与国内外常模比较,同时对家长进行辨证分型,根据证型采用耳穴埋籽的方法进行干预,治疗2个月后再次使用症状自评量表进行评分。结果:患儿家长的躯体化、抑郁、焦虑3个因子分与常模比较有显著性差异(P<0.05);经耳穴埋籽治疗后治疗组在抑郁、焦虑方面较前有了一定改善(P<0.05),对照组则无明显改善。结论:精神发育迟缓患儿家长的心理健康水平普遍较低,耳穴埋籽可在一定程度上改善家长的心理健康水平。%Objective: To investigate the therapeutic effect of seed-embedding method in the auricular points on family members psychological health of parents of children with mental retardation (MR). Methods: Overall 105 family members of MR children were randomly divided into two groups, both of which were measured by symptom checklist (SCL-90) and compared with norm at home and abroad. Furthermore, after intervened with auricular seed-embedding therapy for two months according to the types classified by syndrome differentiation, the parents were scored by SCL-90 again. Results: There was significant difference in the comparison of the scores of somatiza-tion, depression, anxiety between the treatment group and the norm group (P<0.05); family members depression and anxiety in the treatment group were greatly improved after administered the auricular seed-embedding therapy (P<0.05), while the norm group had no obvious improvement. Conclusion: Although the lower healthy levels are commonly encountered in the family members of MR children, the auricular seed-embedding therapy can ameliorate the mental conditions of family members with MR children to a certain extent.

  11. Suicidio por arma de fuego Suicide by firearm

    OpenAIRE

    M. Soriano Maldonado; P. Martínez-García

    2005-01-01

    El mecanismo elegido para cometer el suicidio depende de numerosos factores personales y sociales. En este número presentamos una imagen del tipo de suicidio más mediático, aunque no por ello el más frecuente en nuestro medio. La variabilidad en la forma de los orificios de entrada y salida por arma de fuego depende de la distancia, tipo de arma y región anatómica por lo que puede presentar una morfología muy variada. Es por ello que, aunque ya se han publicado varias imágenes de suicidio por...

  12. 耳甲腔软骨皮瓣旋转联合耳后舌形皮瓣矫正杯状耳%Correction of cup ear by rotation of auricular concha cartilage skin flap and postauricular tongue-shaped flap

    Institute of Scientific and Technical Information of China (English)

    刘闪; 谭谦; 吴杰; 郑东风; 周宏礽; 许澎; 王淑琴; 葛华强

    2011-01-01

    Objective To discuss a new method to correct the moderate and severe congenital cup ear deformities. Methods From May 2005 to August 2009, totally 13 patients ( moderate in 10 cases and severe in 3 cases) with congenital cup ear deformity were corrected by rotation of auricular concha cartilage flap and postauricular tongue-shaped skin flap. Results After 3 to 24 months follow-up, 10 patients were all satisfied with expanded helix , enlarged cavum conchae and nearly normal auricle. Conclusion The application of rotation of auricular concha cartilage flap and postauricular tongue-shaped skin flap can obtain the satisfactory results in correcting moderate and severe congenital cup ear deformities.%目的 探讨一种简明有效的手术方法,矫正中重度杯状耳畸形.方法 自2005年5月至2009年8月,应用耳甲腔软骨皮瓣旋转联合耳后舌形皮瓣,修复中重度杯状耳畸形13例,其中中度者10例,重度者3例.结果 对10例患者术后随访3~24个月,术后耳轮舒展,耳甲腔扩大,耳郭接近正常大小,效果满意.结论 采用耳甲腔软骨皮瓣旋转加耳后舌形皮瓣矫正中重度杯状耳畸形,可取得较满意的效果.

  13. Brain response to transcutaneous electronical stimulation on auricular concha of the healthy subjects using fMRI%经皮电针刺激正常人耳甲迷走神经的功能MRI脑效应研究

    Institute of Scientific and Technical Information of China (English)

    方继良; 刘志顺; 朱兵; 孔健; 荣培晶; 洪洋; 范洋洋; 刘军; 马云遥; 徐春华; 王鸿红; 马迎歌; 王小玲

    2014-01-01

    Objectives: To investigate the BOLD fMRI response to transcutaneous vagus nerve electronical stimulation (tVNS) at auricular concha region (ACR) on the healthy. It is hypothesized that tVNS modulates the network of nucleus of tract solitary-limbic system. Materials and Methods: Sixteen healthy subjects (18-27 y) were enrolled in the fMRI study. The fMRI was conducted during tVNS on ACR controlled with sham-tVNS on the superior scapha respectively. Subjects’ sensations were recorded after every fMRI scan. Each functional scan lasted 6 minutes. SPM8 was employed for the fMRI data processing.Results: The current, and the sensations’ frequency and strength of electronical stimulation were similar between two groups. The tVNS induced the predominant deactivation in the left nucleus of tract solitary and brain regions involving in limbic function, and the activation was limited in left SII, left anterior insula, etc. However, the sham tVNS showed the deactivation in the areas of right nucleus of trigeminal nerve, the obvious activation in the somato-sensory areas. Conclusions: tVNS modulated the network of nucleus of tract solitary-limbic system. It would provide the basis of therapeutic mechanism of tVNS treating Depression.%目的:探讨耳甲迷走神经刺激术的脑通路,为耳迷走神经刺激调制孤束核-边缘叶脑网络假说提供证据。材料与方法随机录用16名健康志愿者,参加经皮电刺激右耳甲部迷走神经分布区(tVNS),以同侧上耳舟部刺激为对照,记录刺激的耳部感觉,观察全脑6 min扫描的Bold-fMRI信号变化,分析脑功能激活特点,应用SPM8处理fMRI数据。结果两组电流、感觉频率及强度未见明显区别。经皮电刺激耳甲部tVNS正常人激发了左侧孤束核及边缘叶脑区广泛而较强的负激活效应,局限性激活位于体感区及岛叶等,而对照部产生了右侧三叉神经核等脑干核团负激活及脑部体感区明显的激活现

  14. Propriedades do Polestireno Modificado por Nanomateriais

    OpenAIRE

    Oliveira, Pedro Xavier Valente de

    2011-01-01

    A incorporação de nanocargas metálicas em matrizes poliméricas, transformando-as em nanocompósitos, constitui um desafio para a investigação em engenharia, no sentido de se dispor de materiais com melhor desempenho físico/mecânico em serviço. No presente estudo foi efectuada a caracterização de nanocompósitos de matriz polimérica reforçada, primeiro por uma carga metálica nanocristalina e posteriormente com adição de nanotubos. A matriz era poliestireno e os reforços nanocristalinos de aç...

  15. Hiperparatiroidismo primario por adenoma paratiroideo mediastinal

    OpenAIRE

    Jeffry Solís-Torres; Esteban Mora-Segura

    2015-01-01

    El hiperparatiroidismo primario cursa con un aumento de la secreción de hormona paratiroidea, generalmente debido a un adenoma, e hipercalcemia. Su presentación clásica se diagnostica con la determinación de calcio sérico y de hormona paratiroidea, asociada con estudios de imágenes. Su tratamiento es quirúrgico y tiene altas tasas de éxito. Se analiza el caso de una paciente hipertensa, de 63 años, con historia de pérdida de apetito y debilidad de un año y medio de evolución, por lo que se le...

  16. La Violencia Latinoamericana vista por los Economistas

    Directory of Open Access Journals (Sweden)

    Salama Pierre

    2003-08-01

    Full Text Available

    Salama, Pierre. "La Violencia Lationoamericana vista por los Economistas", Cuadernos de Economía, V. XXII, n. 38, Bogotá, 2003 páginas 179-198.

    Este articulo sintetiza los estudios económicos publicados recientemente sobre la violencia en América Latina y analiza las causas suceptibles a acrecentarla: pobreza, desigualdad de los ingresos en nivel y variación, impunidad, diferencia entre la probabilidad de ser arrestado y la severidad de la pena impuesta, y narcotrafico. Sin embargo, la explicación de la violencia no se limitará a los factores económicos, puesto que el autor privilegia un enfoque inspirado en la antropología y la sociología.

  17. Síndrome cerebeloso por amiodarona

    Directory of Open Access Journals (Sweden)

    Neuda S. Garretto

    1994-12-01

    Full Text Available La amiodarona (AMD es una droga antiarritmica cuyos efectos adversos pueden comprometer el sistema nervioso central y periferico. La aparición de un síndrome cerebeloso es infrecuente. Se presenta un paciente masculino de 56 anos de edad que desarolla un síndrome pancerebeloso de 4 meses de evolución, que revierte luego de la suspension de la AMD. El cuadro reaparece meses mas tarde luego de un periodo de automedicacion con la droga. Los mecanismos tóxicos por los cuales la AMD afecta al cerebelo permanecen inciertos. Esta droga de amplia difusión en nuestro medio, como otros antiarritmicos, posee efectos sobre el sistema nervioso que deben ser tenidos en cuenta a fin de poder detectarlos precozmente.

  18. Vayamos por partes... dijo Jack el Destripador

    Directory of Open Access Journals (Sweden)

    Miguel Baños González

    2012-04-01

    Full Text Available En la cada día más compleja actividad de comunicación comercial, la publicidad es solamente una herramienta más con diferentes grados de importancia en función del tipo de anunciante. La tendencia a dividir el proceso creativo hasta definir una estructura de fases sucesivas, y en muchos casos de obligado seguimiento, es una visión que se aleja notablemente de la práctica profesional y de la realidad de un mercado holista y global. Por eso, proponemos un cambio de enfoque, analizando la creatividad publicitaria desde una perspectiva que nos permita un conocimiento más profundo, tanto desde punto de vista académico como desde el profesional. 

  19. Toxicidad por óxido de etileno

    Directory of Open Access Journals (Sweden)

    Téllez M. Jairo A.

    1993-08-01

    Full Text Available

    El óxido de etileno, es un compuesto epóxido gaseoso, ampliamente utilizado en nuestro medio como agente esterilizante y de desinfección en instituciones hospitalarias. Los estudios realizados en varios países han demostrado efectos sobre la salud humana, caracterizados por  hipersensibilidad dérmica, irritación del tracto respiratorio, irritación ocular, excitación del S.N.C. y se asocia con presencia de abortos expontáneos, aberraciones cromosómicas e irritación crónica de laringe y tráquea en personal expuesto ocupacionalmente.

  20. fluidizado por proceso autotérmico

    Directory of Open Access Journals (Sweden)

    ZULAMITA ZAPATA BENABITHE

    2005-01-01

    Full Text Available El presente trabajo se basa en el estudio de la producción de carbón activado a partir de carbón mineral subbituminoso en un reactor de lecho fluidizado por proceso autotérmico. El carbón utilizado provino de la región de Amagá (Antioquia - Colombia y fue activado en dos reactores de lecho fluidizado de diferente diámetro interno, 10 cm y 22 cm. Los valores del área superficial específica y el volumen de poro de las muestras activadas fueron determinados a partir de las isotermas de N2 y CO2. Los resultados experimentales mostraron que los valores de áreas superficiales BET y DR y del Índice de Yodo se encontraron alrededor de 460 m2/g (SBET, 490 m2/g (SDR y 460 mg I2/g carbón.

  1. Herida por arma de fuego Gunshot wounds

    OpenAIRE

    A. Sibón Olano; P. Martínez-García; E. Santiago Romero

    2003-01-01

    En el examen de las heridas por arma de fuego, hay que prestar especial interés al orifico de entrada. Un examen minucioso del mismo, nos permitirá conocer la distancia a la que se ha efectuado el disparo; así mismo, nos orientará sobe la trayectoria y etiología médico-legal. El tipo de arma puede modificar en alguna medida el orificio de entrada en los disparos a cañón tocante; como ocurre en las armas de dos cañones, en las que tiene situada su mira en la boca del cañón, o en las que están ...

  2. Choque séptico por ehrliquiosis

    Directory of Open Access Journals (Sweden)

    Viviana Hernández-de Mezerville

    2007-04-01

    Full Text Available La ehrliquiosis humana es una infección zoonótica transmitida por "garrapatas duras" causada por Anaplasma sp y Ehrlichia sp. Puede presentarse como un cuadro pseudogripal con fiebre, malestar general, mialgias y cefalea o hasta un choque séptico con falla multiorgánica y muerte. La mitad de los pacientes requieren atención hospitalaria en algún momento y se reporta una mortalidad de hasta el 5% secundaria a enfermedades oportunistas o a hemorragias. El diagnóstico se puede sospechar visualizando las mórulas intracitoplasmáticas en las células afectadas en frotis de sangre periférica, y se confirma con serología, con cultivos o con detección molecular. El tratamiento de elección es la doxiciclina con buena respuesta clínica. Se reporta un caso probable de ehrliquiosis humana asociado a choque séptico y falla multiorgánica tratado exitosamente en el Hospital Dr. Rafael Angel Calderón Guardia.Human ehrlichiosis is a tick-borne infectious disease caused by Anaplasma sp and Ehrlichia sp. The presentation can range from a flu-like syndrome with fever, malaise, myalgia and headache to a septic shock state with multiorganic dysfunction. Half the patients require in- hospital care and the mortality rate is 5% as a result of opportunistic infections or hemorrhage. The diagnosis can be made by the visualization of intracytoplasmatic morulae in the blood smear, serology, cultives or polymerase chain reaction. The treatment of choice is doxycicline and generally carries a good response. We report a case of human ehrlichiosis associated with septic shock and multiorganic dysfunction successfully treated at the Calderon Guardia Hospital.

  3. Hiperparatiroidismo primario por adenoma paratiroideo mediastinal

    Directory of Open Access Journals (Sweden)

    Jeffry Solís-Torres

    2015-06-01

    Full Text Available El hiperparatiroidismo primario cursa con un aumento de la secreción de hormona paratiroidea, generalmente debido a un adenoma, e hipercalcemia. Su presentación clásica se diagnostica con la determinación de calcio sérico y de hormona paratiroidea, asociada con estudios de imágenes. Su tratamiento es quirúrgico y tiene altas tasas de éxito. Se analiza el caso de una paciente hipertensa, de 63 años, con historia de pérdida de apetito y debilidad de un año y medio de evolución, por lo que se le realizaron exámenes de laboratorio que revelaron hipercalcemia y elevación de la hormona paratiroidea. Se le indicó entonces una gamagrafía con Tecnecio 99, que evidenció un nódulo de 18mm de diámetro, ubicado 2 centímetros caudal al lóbulo tiroideo derecho. Se le efectuó una exploración cervical sin encontrarse la lesión, por lo que requirió una esternotomía media superior, que permitió encontrar un adenoma en el mediastino superior, detrás de la vena braquiocefálica derecha, de manera que se procedió a su extracción. Los controles de calcio y de hormona paratiroidea a las 24 horas estaban entre los límites normales, y se egresó.

  4. Auricular Acupressure Can Modulate Pain Threshold.

    Science.gov (United States)

    Santoro, Antonietta; Nori, Stefania Lucia; Lorusso, Letizia; Secondulfo, Carmine; Monda, Marcellino; Viggiano, Andrea

    2015-01-01

    The objective of our study was to investigate if auriculotherapy (AT) can modulate pain threshold. In our experiments, AT consisted of placing Vaccaria seeds over the "fingers point" of one ear. Two groups of healthy volunteers were enrolled for the study. Each subject was asked to perform an autoalgometric test developed by our group on three occasions: before, 1 hour after, AT and 24 hours after AT. Participants of the first group received a 2-minute long session of AT, while participants of the second group received a 2-minute long session of sham treatment, consisting of a puncture/massage above the skin of the neck. The autoalgometric test consisted of applying an increasing pressure with the finger-tips and finger-backs of four fingers by the subjects themselves (i.e., eight sites were evaluated) against a round-shaped needle for two times: until a minimum pain sensation (first time, minimal test) or a maximally tolerable pain sensation (second time, maximal test). Our results showed a significant higher pain threshold in the maximal test at 24 hours after AT compared to sham treatment. This result indicates for the first time that AT can increase pain tolerability, rather than affecting the minimal pain threshold. PMID:26236378

  5. Auricular Acupressure Can Modulate Pain Threshold

    Directory of Open Access Journals (Sweden)

    Antonietta Santoro

    2015-01-01

    Full Text Available The objective of our study was to investigate if auriculotherapy (AT can modulate pain threshold. In our experiments, AT consisted of placing Vaccaria seeds over the “fingers point” of one ear. Two groups of healthy volunteers were enrolled for the study. Each subject was asked to perform an autoalgometric test developed by our group on three occasions: before, 1 hour after, AT and 24 hours after AT. Participants of the first group received a 2-minute long session of AT, while participants of the second group received a 2-minute long session of sham treatment, consisting of a puncture/massage above the skin of the neck. The autoalgometric test consisted of applying an increasing pressure with the finger-tips and finger-backs of four fingers by the subjects themselves (i.e., eight sites were evaluated against a round-shaped needle for two times: until a minimum pain sensation (first time, minimal test or a maximally tolerable pain sensation (second time, maximal test. Our results showed a significant higher pain threshold in the maximal test at 24 hours after AT compared to sham treatment. This result indicates for the first time that AT can increase pain tolerability, rather than affecting the minimal pain threshold.

  6. Current Treatment Options for Auricular Hematomas.

    Science.gov (United States)

    MacPhail, Catriona

    2016-07-01

    Ear disease, such as otitis externa, resulting in aggressive head shaking or ear scratching, is the most common cause of the development of aural hematomas in dogs and cats. An underlying immunologic cause has also been proposed to explain cartilage and blood vessel fragility. Numerous options exist for management of aural hematomas, from medical management alone with corticosteroids, to simple hematoma centesis, to surgical intervention. Because this condition is usually secondary to another disease process, regardless of mode of treatment, likelihood of recurrence is low if the underlying condition is managed properly. PMID:27012935

  7. Intoxicações natural e experimental por amitraz em eqüídeos: aspectos clínicos Natural and experimental poisoning by amitraz in horses and donkey: clinical aspects

    Directory of Open Access Journals (Sweden)

    Marcos Dutra Duarte

    2003-09-01

    Full Text Available A administração oral e a aspersão com amitraz reproduziram experimentalmente em 17eqüinos e um asinino um quadro de intoxicação muito similar a outro que vinha ocorrendo em cavalos no Estado do Rio de Janeiro. O início dos sintomas após a administração oral variou entre 15min. e 2h05min., na aplicação por aspersão variou entre 6h28min. e 8h38min. A evolução nos casos de administração oral foi de 4 a 9 dias, nos de aspersão de 5 a 6 dias. Somente morreram animais que receberam a administração oral. Um animal aspergido com o amitraz foi sacrificado. Por via oral foram usadas dosagens de 5,5 mg/kg (uma administração, 5,8 mg/kg (duas administrações e num terceiro animal, doses que variaram entre 7,2 e 36,4 mg/kg (cinco administrações. Nas aplicações por aspersão, a intoxicação foi reproduzida com soluções nas concentrações de 0,1 e 0,2%. Com relação ao sistema nervoso, os principais sinais observados foram apatia, sonolência, ptoses palpebral e auricular, dificuldade de apreensão, mastigação e deglutição do alimento, arrastar das pinças dos cascos no solo, exposição do pênis, sensibilidade cutânea diminuída/ausente, instabilidade em estação, abdução dos membros, cabeça baixa, incoordenação, bocejos, flacidez labial, exposição da língua, cruzamento dos membros ao caminhar, resposta postural diminuída após cruzar e abduzir os membros, reflexos do lábio superior, palatal, lingual, de deglutição e flexor diminuídos/ausentes, reflexos auricular, palpebral e de ameaça diminuídos e resposta ambulatória diminuída ao teste de girar em círculo de pequeno raio. No que se refere ao sistema digestivo, foram evidenciados, principalmente, hipomotilidade/atonia intestinal, edema dos lábios, distensão abdominal, deitar e levantar com freqüência, rolar no solo, olhar para o flanco, gemer e impactação do intestino grosso. Observaram-se ainda taquicardia, aumento do tempo de preenchimento

  8. Valor del BNP y de la proteína C reactiva en el diagnóstico diferencial entre angina primaria y secundaria por hipertensión arterial

    Directory of Open Access Journals (Sweden)

    Enrique P. Gurfinkel

    2006-01-01

    Full Text Available Introducción A los episodios de inestabilidad anginosa precipitados por causas secundarias que, no infrecuentemente, no pueden discernirse de razones primarias se les concede poca atención. El presente trabajo intenta responder si algunos biomarcadores pueden contribuir a identificar a aquellos individuos con angina IIIb de los conocidos como anginosos IIIa de la clasificación de Braunwald. Material y métodos En total, participaron del ensayo 64 pacientes seleccionados. De éstos, 33 tuvieron diagnóstico final de angina inestable secundaria a hipertensión arterial y 21 de angina primaria, en tanto que 10 enfermos anginosos estables, referidos para la práctica de un estudio angiográfico diagnóstico, sirvieron de control. En todos ellos, en el momento de la admisión se obtuvieron alícuotas de sangre venosa para la determinación del péptido natriurético auricular tipo B (BNP y de proteína C reactiva ultrasensible (hs-CRP, y luego se realizó un estudio angiográfico invasivo a fin de analizar la carga aterosclerótica con puntajes (scores angiográficos. Resultados Los pacientes con angina primaria tuvieron una extensión aterosclerótica mayor en la angiografía (p < 0,025, más vasos comprometidos (p = 0,029 y un porcentaje mayor de estenosis (p < 0,001 que los anginosos secundarios. Los pacientes controles presentaron valores de BNP de 133 pg/mL (41; 224 [mediana (percentiles 25 y 75] y de 1,6 mg/L (0,4; 3,6 de hs-CRP. Los anginosos primarios no difirieron de los controles: 129 (95; 231 y 4,0 (2,0; 5,6 para BNP y hs-CRP, respectivamente. Los anginosos secundarios tuvieron valores de 73 (19; 325 y de 4,5 (2,2; 9,0, respectivamente. No hubo diferencias significativas entre ambos cuadros anginosos: p = 0,458 para BNP y p = 0,552 para hs-CRP. Conclusiones Independientemente de la carga aterosclerótica elevada en los anginosos primarios, el BNP y la hs-CRP no reconocieron con precisión la inestabilidad clínica inducida por un

  9. ¿Inconstitucionalidad por omisión?

    Directory of Open Access Journals (Sweden)

    Alfredo Quispe Correa

    2006-01-01

    Full Text Available El autor realiza un análisis del sistema peruano de control de constitucionalidad desarrollado en control abstracto por el Tribunal Constitucional y en control concreto por los tribunales de justicia, para luego centrar su análisis sobre la inconstitucionalidad por omisión, considerando la doctrina desarrollada en la materia, planteando sus reservas en la materia, especialmente cuando el tribunal constitucional se convierte en legislador positivo.

  10. Estudio electrofisiologico en la neuropatia por Vincristina

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    Olga P. Sanz

    1975-12-01

    Full Text Available Diez pacientes afectados por diversas patologías que requerían tratamiento crónico con Vincristina, fueron sometidos a estudios electrofisiológicos en los que se valoró: el número de unidades motoras (UM funcionantes en los músculos de la eminencia tenar, los valores de los incrementos medios de UM, velocidad de conducción motora y su latencia residual en el nervio mediano, la velocidad de conducción sensitiva del mismo nervio y el estado de la transmisión neuromuscular. Los valores obtenidos fueron comparados con grupos controles. Los resultados mostraron disminución del número de UM; las UM remanentes presentaron amplitud reducida junto a otras cuyo tamaño no superaba el del grupo control, hecho que sugiere la incapacidad de lograr una reinervación adecuada. Las velocidades de conducción motora y sensitiva mostraron valores diminuídos, con mayor compromiso en los segmentos distales. Junto a estos datos se halló respuesta miasteniforme al estímulo repetitivo. Todos estos resultados permiten postular la existencia de un compromiso de la unidad motora, abarcando todos sus segmentos, en pacientes intoxicados con Vincristina.

  11. Por uma nova ética ambiental

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    Edna Parizzi de Viveiros

    2015-09-01

    Full Text Available RESUMOEste artigo procura abordar a relação do homem com o ambiente. Entre outros pontos de discussão, argumenta que o cientificismo contribuiu para que se aprofundasse a visão de posse absoluta e exploração implacável sobre a natureza (terra, água, florestas, e que as fragilidades apresentadas pelo Planeta na atualidade são resultados do modo pelo qual se deu essa relação, ou seja, o modo como a partir do "domínio" sobre a natureza, o homem dilapidou e continua dilapidando os recursos naturais, com o intuito de produzir cada vez mais bens para o consumo, gerar e concentrar riquezas. Por fim, o artigo trata da emergência da educação ambiental e da prática interdisciplinar entre saberes, para que se possa construir uma nova ética ambiental, tão necessária à sobrevivência do Planeta.

  12. Libertad, igualdad, sostenibilidad. Por un ecofeminismo ilustrado

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    Puleo, Alicia H.

    2008-06-01

    Full Text Available This article presents the proposal of an enlightened Ecofeminism and defines it as an ethic-political thinking about human relations to Nature. It aims at ecojustice and sustainability, which are characterized through the criticism of prejudice, through the principles of equality and autonomy, and through the nominalist conceptualization of gender, intercultural dialogue and the sensible acceptance of science and technique. The enlightened Ecofeminism universalizes virtues such as caring for the human and non-human Nature, and defends a compassionate moral towards the radical finitude of the world.

    En este artículo se presenta la propuesta de un ecofeminismo ilustrado entendido como reflexión ético-política sobre las relaciones de los humanos con la Naturaleza. Orientado a la ecojusticia y la sostenibilidad, el ecofeminismo ilustrado se caracterizaría por la crítica al prejuicio, la defensa de los principios de igualdad y autonomía, la conceptualización nominalista del género, el diálogo intercultural, la aceptación prudente de la ciencia y la técnica, la universalización de las virtudes del cuidado aplicadas a los humanos y al resto de la Naturaleza, y una moral de la compasión frente a la radical finitud del mundo.

  13. Identidad e interculturalidad: un horizonte por visitar

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    Marian Pérez Bernal

    2016-01-01

    Full Text Available En el presente trabajo mantenemos que el concepto de identidad defendido por Amin Maalouf puede ser una interesante vía para conseguir una aproximación entre las distintas culturas capaz de conducirnos a un diálogo fructífero que nos permitan gestionar la multiculturalidad actual. Defendemos que las culturas sean vistas como escenas de debate y contestación en constante proceso de construcción y reconstrucción y en las que siempre primen unos valores que nos conciernen a todos y que han de ser irrenunciables.In this paper, it is stated that the concept of identity defended by Amin Maalouf could be an interesting way to achieve a rapprochement amongst different cultures. This could lead to a fruitful dialog allowing to manage today’s multiculturalism. It is also defended that cultures should be considered as instruments of debate and reply on a continuous process of construction and reconstruction. However, cultures should not prevail over a series of values that concern to all of us and that should be inalienable.

  14. Herida por arma de fuego Gunshot wounds

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    A. Sibón Olano

    2003-01-01

    Full Text Available En el examen de las heridas por arma de fuego, hay que prestar especial interés al orifico de entrada. Un examen minucioso del mismo, nos permitirá conocer la distancia a la que se ha efectuado el disparo; así mismo, nos orientará sobe la trayectoria y etiología médico-legal. El tipo de arma puede modificar en alguna medida el orificio de entrada en los disparos a cañón tocante; como ocurre en las armas de dos cañones, en las que tiene situada su mira en la boca del cañón, o en las que están dotadas de bocacha apagafuegos.When examining firearm wounds, special attention must be paid to the entrance wound. Meticulous examination will establish the range at wich the shot was fired as well as the trajectory and the manner of death (forensic etiology. In a contact gunshot wound, the type of weapon can modify the entrance wound to some extent. This is what happens in double barrel muzzle or in those endowed with a fireguard.

  15. Estrategias de crecimiento empresarial aplicadas por hipermercados

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    Miraidy Leal Morantes

    2003-01-01

    Full Text Available El presente estudio tiene como objetivo caracterizar las estrategias de crecimiento empresarial, representadas por alianzas y adquisiciones, que han sido aplicadas en el sector de distribución de bienes de consumo masivo, específicamente en los hipermercados ubicados en Maracaibo, Estado Zulia, como manera de responder al entorno competitivo y cambiante en el cual se desenvuelven. La investigación se desarrolló a través de un estudio de carácter descriptivo; para la recolección de datos se aplicó un cuestionario estructurado, bajo la modalidad de entrevista, a gerentes generales y financieros. Los resultados evidencian que las estrategias de crecimiento empresarial utilizadas son la apertura de nuevos establecimientos comerciales, adquisición de empresas y participación accionaria en grandes cadenas, las cuales propician la concentración del mercado de distribución comercial, afectando a algunas empresas venezolanas del sector cuya oferta no puede competir; asimismo, los proveedores se enfrentan a cadenas con gran poder de negociación.

  16. La responsabilidad del Estado por el hecho del legislador

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    María Consuelo Alonso; Eric Leiva Ramírez

    2011-01-01

    Analizar el fenómeno de la responsabilidad del Estado causada por los hechos del legislador ha sido un trabajo desarrollado tanto por la doctrina como por la jurisprudencia internacional a mediados del siglo xx. En Francia, por ejemplo, se presentó el primer antecedentejurisprudencial en el año de 1934. En España, su estudio empezó a gestionarse con la promulgación de la Constitución de 1978, dándose el primer fallo judicial en el año de 1993. Para el caso colombiano, la Constitución de 1991 ...

  17. Epidemiología de la incapacidad temporal por contingencia común por neoplasias en España

    OpenAIRE

    Díez García, Raquel

    2014-01-01

    [ES]Objetivos: Conocer la incidencia de neoplasias en una población trabajadora perteneciente a empresas cuyos episodios de Incapacidad Temporal (IT) por Contingencia Común estaban gestionados por una Mutua de Accidentes de Trabajo y Enfermedades Profesionales de ámbito estatal. Material y Método: Estudio descriptivo, observacional y retrospectivo. Se contabilizaron los casos de neoplasias registrados en la población trabajadora protegida por la Mutua durante el periodo comprendido entre e...

  18. Motivado por cirujanos Motivated by Surgeons

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    Carlos Salazar-Vargas

    2010-12-01

    Full Text Available Comenzaba la década de los 60 y nuestro grupo nerviosamente iniciaba lecciones en los hospitales de San José. En aquellos años, el estudiante de medicina empezaba su contacto con pacientes, por lo menos 1 ó 2 años después de iniciada la carrera. El estudio del ser humano normal que ya habíamos concluido, continuaba con el del enfermo, y más adelante aprenderíamos el tratamiento. La enfermedad descrita en el libro, de pronto se convertía en un enfermo, y es a este quien hoy veíamos, cohibido pero inquisidor, en la cama de un hospital. Los profesores nos enseñaban a interrogar y a examinar a los pacientes, y cada gesto suyo, cada pregunta, cada maniobra, eran celosamente guardados en la memoria de los educandos. Con claridad percibíamos, aun a temprana edad, las diferencias entre los especialistas, y casi de manera involuntaria, cada quien iba tomando partido y escogía su futuro camino. Fue durante esos tempranos años, cuando mi vida se cruzó con la de 7 maravillosas personas y excelentes cirujanos, que marcaron para siempre mi destino y, sin quererlo ellos, me hicieron inclinarme por la cirugía. Dos eran serios y profundamente académicos: el Dr. Manuel Aguilar Bonilla y el Dr. Vesalio Guzmán Calleja; 3, decididos, incansables y muy hábiles: el Dr. Longino Soto Pacheco, el Dr. Claudio Orlich Carranza y el Dr. Carlos Prada Díaz, y 2, abordables, prácticos, joviales y amistosos: el Dr. Fernando Valverde Soley y el Dr. Randall Ferris Iglesias….During the early 60´s our class just started clinical lessons in different hospitals of San Jose. In those years the medical student became in contact with patients 1 or 2 years after initiating his or her career. The study of the normal human being continued with that of the diseased and later on we would learn how to treat our patients. The disease described in our textbooks, suddenly was a reality, a person lying in a hospital bed, shy but inquisitive. Our teachers taught us how to

  19. 低能量激光照射加耳穴贴压治疗中重度突发性耳聋%Moderate and severe sudden deafness treated with low-energy laser irradiation combined with auricular acupoint sticking

    Institute of Scientific and Technical Information of China (English)

    周国赢

    2012-01-01

    Objective To test the therapeutic effect on moderate and severe sudden deafness treated with lo-wenergy laser irradiation on acupoint and external auditory canal combined with auricular point sticking (APS) and as compared with electroacupuncture. Methods Two hundred and fifty-eight cases of moderate and severe sudden hearing loss were randomly divided into an observation group 1, an observation group 2 and a control group, 86 cases in each group. In three groups, 10% low molecular Dextran 500 mL were used for intravenous infusion. Based on the above treatment, the observation group 1 was treated with low-energy laser irradiation on acupoinr and external auditory canal (such as ErmenCTE 21). Tinggong(SI 19) and TinghuiCGB 2)), combined with APS at Gan (liver) , Shen(kidney) and Neifenmi (endorine) ,etc. The observation group 2 was treated with electroacupuncture at the same acupoints as those point irradiation in observation group 1. Fifteen days made one session. The therapeutic effects were evaluated after one and two sessions. Results After two sessions, The cured rate was 40. 7% (35/86) in observation group 1 and 38. 4%(33/86) in observation group 2,which were superior to 25. 6%(22/86) in control group(both P<0. 05). Compared with one session, the therapeutic effects after two sessions were better in two observation groups(both P<0.05), but there was no significant difference between two groups(both P> 0.05). In comparison of the improvements of frequency audiometry and auditory function, the two observation groups were better than those in control group(P<0. 05 ,P<0. 01), and the improvements after two sessions were better in two observation groups(both P<0. 01). Conclusion Both of low-energy laser irradiation on acupoint and external auditory canal combined with APS and electroacupuncture are able to decrease frequency audiometry, improve auditory function, and the therapeutic effects are better with prolongation of treatment time. The clinical

  20. 电针配合耳穴贴压对肥胖伴多囊卵巢综合征患者血清胰岛素及睾酮的影响%Effect of electroacupuncture combined with auricular point tapping and pressing on serum insulin and testosterone in the patients of obese women with polycystic ovary syndrome

    Institute of Scientific and Technical Information of China (English)

    徐佳; 曲惠卿; 方海琳

    2009-01-01

    Objective To assess the therapeutic effect and mechanism of electroacupuncture combined with auricular point tapping and pressing on the obese women with polycystic ovary syndrome. Methods Thirty-nine cases of obese women with polycystic ovary syndrome were treated with electroacupuncture combined with auricular point tapping and pressing, body points as Tianshu (ST 25), Fenglong (ST 40), Guanyuan (CV 4) and Siman (KI 14) etc. Were selected, and ear points as Kou (mouth), Wei (stomach) and Pi (spleen) etc. Were selected. After 3 courses, the therapeutic effect, the body mass index (BMI), the waist circumference (WC) and the changes of the serum insulin (Ins) and testosterone (T) were compared before and after treatment. Results Of the 39 cases, 10 cases were cured, 25 cases were effective, 4 cases were ineffective, with a total effective rate of 89. 7%; there were significant differences in BMI, WC, Ins and T of the patients compared with that before treatment (all P<0. 01). Conclusion Electroacupuncture combined with auricular point tapping and pressing has a good clinical effect on obese women with polycystic ovary syndrome, the treatment mechanism may realized by regulating the serum insulin and the testosterone of the patients.%目的:评价针刺配合耳穴贴压对肥胖女性伴多囊卵巢综合征的疗效,探讨其机制.方法:采用电针及耳穴贴压治疗肥胖女性伴有多囊卵巢综合征39例,体穴取天枢、丰隆、关元、四满等穴,耳穴取口、胃、脾等.3个疗程后,将患者疗效,治疗前后的体质量指数(BMI)、腰围(WC)以及血清中胰岛素(Ins)、睾酮(T)的变化进行对比.结果:39例患者中痊愈10例,有效25例,无效4例,总有效率达89.7%;患者的BMI、WC、Ins、T与治疗前对比均显著降低,差异均有统计学意义(均P<0.01).结论:电针、耳穴贴压对肥胖女性伴有多囊卵巢综合征有较好的临床疗效,其治疗机制可能是通过对患者血清中

  1. Observation of Huyiyin combined with auricular acupuncture on new-onset type 2 diabetic insulin resistance%护胰饮加减联合耳针治疗新发2型糖尿病胰岛素抵抗43例临床观察

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    徐江红; 朱立春; 张振锋; 杜蕊

    2013-01-01

    Objective To investigate the effect of Huyiyin combined with auricular acupuncture on new - onset type 2 diabetic insulin resistance. Methods 126 patients with new - onset type 2 diabetic insulin resistance were randomly divided into three groups. 40 cases in diet and exercise group received conventional diet and exercise therapy. 43 patients in Huyiyin group received Huyiyin combined with auricular point therapy. 43 patients in metformin group received metformin treatment. The course was three months in three groups. Results The overall clinical efficiency and total efficiency of improving insulin resistance in Huyiyin group was higher than that in diet and exercise group (P <0.05). Clinical efficacy and improving insulin resistance efficacy in Huyiyin group was higher than that in diet and exercise group. FPG, 2h PG, FINS, BMI, TG and HOMA - IR in Huyiyin group were decreased as compared with those in diet and exercise group after treatment (P < 0.05, P < 0. 01). 2h PG, BMI and TG in Huyiyin group were decreased as compared with those in metformin group after treatment ( P < 0.05, P <0.01). Conclusion Huyiyin combined with auricular acupuncture can significantly improve symptoms, lower blood sugar, increase insulin sensitivity, improve new -onset type 2 diabetic insulin resistance, and without side effects.%目的 观察护胰饮加减联合耳针治疗新发2型糖尿病胰岛素抵抗的临床疗效.方法 将126例新发2型糖尿病胰岛素抵抗患者随机分为3组,饮食运动组40例予常规饮食运动治疗,护胰饮加减联合耳针组43例予护胰饮加减联合耳针治疗,二甲双胍组43例子盐酸二甲双胍片治疗.3组均3个月为1个疗程,治疗1个疗程后观察疗效.结果 护胰饮加减联合耳针组临床总有效率和改善胰岛素抵抗总有效率均高于饮食运动组(P<0.05),护胰饮加减联合耳针组临床疗效和改善胰岛素抵抗疗效优于饮食运动组.护胰饮加减联合耳针组治疗后空

  2. Study on the effects of auricular point magnetotherapy with cognitive behavioral nursing care on dialysis stability in maintenance hemodialysis patients with depres-sion%耳穴磁疗配合心理护理对血液透析并发抑郁患者透析稳定性的影响

    Institute of Scientific and Technical Information of China (English)

    潘晓东; 张桂燕; 卓缘圆; 聂小兰; 缑燕华; 王玲; 丘凤贤

    2014-01-01

    目的:探讨耳穴磁疗配合心理护理对维持性血液透析并发抑郁的临床疗效。方法选取维持性血液透析并发抑郁症患者80例,随机分为治疗组和对照组,每组40例。对照组患者进行常规血液透析治疗,治疗组在常规血液透析治疗基础上同时进行耳穴磁疗配合认知行为护理疗法。治疗4 w和8 w后统计临床疗效。结果治疗4 w后,治疗组Zung抑郁自评量表评分低于对照组(P<0.01);4 w减分率明显大于对照组(P<0.01)。治疗8w后,治疗组Zung抑郁自评量表评分低于对照组(P<0.01);8 w减分率明显大于对照组(P<0.01)。治疗组患者治疗8 w后高血压、低血糖、心律失常、消化道症状的并发症发生率均低于对照组(均P<0.05)。结论耳穴磁疗配合心理干预对维持性血液透析并发抑郁症的患者透析稳定性具有较好的疗效。%Objective To observe the effect of auricular point magnetotherapy with cognitive behavioral nursing care in the treat -ment of maintenance hemodialysis patients with depression.Methods A total of 80 cases of maintenance hemodialysis patients with depres-sion were randomly divided into treatment group and control group , each group of 40 cases.The treatment group was given routine hemodialy-sis treatment on the basis of auricular point magnetotherapy combined with cognitive behavioral therapy , while the control group was treated with routine hemodialysis therapy only.Curative effect statistics was given after treatment for 4 weeks and 8 weeks.Results After 4 weeks and 8 weeks, SDS scores in two groups were decreased (P<0.05), and 8 weeks after the treatment, SDS score in treatment group was sta-tistically significant compared with the control group (P<0.05) .In addition, after treatment for 4 weeks and 8 weeks, the occur rate of hy-potension, hypertension, arrhythmia, hypoglycemia, gastrointestinal symptoms in two group decreased , and after the

  3. The application of medpor and split-thickness skin graft in formation of cranioauricular sulcus during auricular reconstruction with Nagata method%Medpor和刃厚头皮片在Nagata法耳廓再造耳颅沟成形中的应用

    Institute of Scientific and Technical Information of China (English)

    王美水; 王彪; 郑厚兵; 吴杉英; 单秀英; 刘照亮; 庄福连

    2014-01-01

    目的 探讨Medpor和刃厚头皮片在先天性小耳畸形Nagata法耳廓再造耳颅沟成形中的应用方法及疗效.方法 参照Nagata二期法耳廓再造程序完成一期手术,即肋软骨耳廓支架成型和移植,一期术后6个月后行二期耳颅沟成形:于患侧颞枕部获取与再造耳上部皮肤连续的刃厚皮片,翻起皮片,在再造耳外耳轮外5 mm切开达皮下层,向耳甲腔方向分离并掀起软骨支架;以C形Medpor支架支撑于再造耳支架后方,再造耳支架背面和Medpor表面行带颞浅血管的颞浅筋膜瓣覆盖,最后将刃厚头皮片覆盖于筋膜瓣表面缝合固定,湿纱卷加压固定.结果 2010年7月至2012年8月,于临床应用20例22侧,1例二期术后发现颞浅筋膜瓣部分坏死、支架外露,采用耳后筋膜瓣覆盖及刃厚头皮片移植修复.其余患者均顺利完成二期手术.随访时间为6~18个月,平均13个月,20例22只再造耳术后耳颅沟形状均满意.结论 应用刃厚头皮片和Medpor材料可以获得稳定满意的耳颅沟,且既可避免切取全厚或中厚皮片在供区所遗留的明显瘢痕,又可减少因切取过多的肋软骨对胸廓的创伤.%Objective To investigate the application of medpor and split-thickness skin graft in formation of cranioauricular sulcus during auricular reconstruction with Nagata method.Methods The first stage operation was fulfilled according to the Nagata two-stage method which involves fabrication and grafting of the costal cartilage framework.The second-stage ear elevation operation was undertaken 6 months later to form the cranioauricular sulcus.Split-thickness skin was taken from temporal and accipital area.After releasing the auricular framework and transplanting C shaped medpor at the rear side of framework,the temporaparietal fascia flap was transferred to cover postauricular medpor and framework.Then the split-thickness skin graft was implant on the fascia surface.Results From July 2010 to August

  4. 7.0T磁共振成像观察耳后给药促进药物进入内耳的可行性%Feasibility study of inner ear drug delivery via post-auricular injection using 7.0 Tesla MRI

    Institute of Scientific and Technical Information of China (English)

    李晶兢; 余力生; 夏睿; 郜发宝; 骆文龙; 静媛媛

    2012-01-01

    Objective To investigate the feasibility of postauricular injection as a drug administration route in treating inner ear disorders. Methods Twelve albino guinea pigs were divided randomly into two groups to receive either a post-auricular or intravenous bolus of gadopentetate dimeglumine (Gd-DTPA). A 7.0 Tesla MRI system, specially designed for small animals, was used to observe the signal changes of gadolinium enhanced images of the right cochlea for forty-eight hours. The observation time paints included pre-administration, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, 24 and 48 h post-administration. The relative signal intensity in the right scala tympani of the basal turn was measured to evaluate indirectly the dynamic Gd uptake in the perilymph. The area under the signal-time curve was calculated and compared between the two administration routes. Results Post-auricularly treated guinea pigs revealed a higher area under the signal - time curve from pre-injection to the last time point (P < 0.05). Conclusions Post-auricular injection may be a potential and efficient route for inner ear drug delivery.%目的 借助磁共振成像系统,观察新给药方式耳后给药,药物在内耳的吸收过程,探讨耳后给药治疗内耳疾病的可行性.方法 12只白色红目豚鼠随机分为2组,一组耳后注射造影剂,一组静脉注射造影剂.7.0T小动物专用磁共振成像系统,在给药前、给药后0.5h、1h、2h、3h、4h、6h、8h、12h、24h、48h,分别进行磁共振T1加权像成像.测量右侧耳蜗底转鼓阶的信号强度,描绘信号-时间曲线,计算曲线下面积,对比耳后组与静脉组之间的差异.结果 耳后组与静脉组信号-时间曲线下面积分别为68.14×105及36.17×105,耳后组面积更大,差异有统计学意义(P<0.05).结论 耳后给药治疗内耳疾病是可行的,局部疗效好,全身并发症少,便于在临床推广应用.

  5. Ass essment Report of Preventing and Treating Hypertension with Auricular Therapy Combined with Community-based Intervention%耳穴疗法结合社区干预对高血压病的防治价值评估报告

    Institute of Scientific and Technical Information of China (English)

    唐虹; 刘继洪; 陈健英; 陈海佳; 潘国昌; 钟海声; 孙国强

    2015-01-01

    目的:探讨耳穴疗法结合社区干预对高血压病的防治价值。方法:从白云街社区卫生服务中心已筛查出的社区高血压病居民共3000名中随机抽出360例高血压患者作为实验对象,最后的有效人数是328人,并将其均分为4组( A组:健康教育组,B组:单纯耳穴贴压和耳尖放血组,C组:单纯用药组, D组:用药加耳穴贴压和耳尖放血组),先进行问卷调查,并采用炎黄东方(北京)健康科技有限公司的《中医体质辨识软件》对高血压居民进行体质辨识分析。接着分别给予耳穴疗法、药物及健康教育等干预措施。1年后,对有效人数328位高血压居民再次进行问卷调查和中医体质分析。结果:治疗后患者的血压相对治疗前明显得到改善,有统计学意义( P <0.05)。治疗后,D组患者的血压与其他3组相比,差异最大,有统计学意义( P<0.05)。治疗前,白云街社区高血压居民的高血压病知晓率是65.3%,治疗率是77.77%,控制率是81.66%,平和质、阳虚质、气虚质、痰湿质比例较大,分别为21.73%、17.39%、17.39%、15.4%。治疗后,白云街社区高血压居民的高血压病知晓率是86.29%,治疗率是82.31%,控制率是88.41%,平和质、阳虚质、气虚质、痰湿质比例较大,分别为23.48%、17.68%、17.68%、15.24%。结论:耳穴疗法结合社区干预对于高血压病的防治效果良好,相对于现在单纯的高血压药物治疗模式,更有效控制患者的血压和改善患者的生活质量。生活方式干预,规范用药,应用耳穴贴压和耳尖放血的中西医一体化综合全面防治方案适合在社区范围内广泛推广。%Objective:To discuss the value of preventing and treating hypertension with auricular therapy com-bined with community-based intervention.Methods:Randomly choose 360 cases ( the final valid samples

  6. OPINIÓN: PARA TRABAJAR POR CARTAGENA POR DÓNDE COMENZAR?

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    Carmen Cabrales Vargas

    2004-08-01

    Full Text Available Ciertamente son muchos los flancos desde los cuales acercarnos a esta ciudad que se encuentra en permanente y profunda movilidad con respecto a lo que era hace dos décadas. Cartagena ha estallado y seguirá estallando en muchos pedazos, convirtiéndose en una ciudad que por su compleja dinámica no alcanza a recomponerse en su organización social ni en sus espacios físicos; por ello se nos muestra como un lugar donde la confrontación con el orden instituido para su funcionamiento es permanente. En ese sentido, puede anotarse que son pocos los que acogen con rigor las normas de tránsito o respetan el espacio público, o practican el cuidado ambiental o respetan el derecho del otro al uso de los recursos institucionales que se ofrecen. Dicho de otra forma, en los imaginarios de estos habitantes parece no encontrarse el de la ciudad en cuanto organización espacial con reglas y normas que le dan sentido.

  7. Mujeres por la utilidad de la virtud

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    Nancy Rodríguez Pupo

    2014-08-01

    Full Text Available La mujer cubana ostenta una vasta tradición combativa y es ejemplo de entereza, abnegación, sacrificio y compromiso social. Quien se acerque a la historia de nuestro proceso nacional-liberador a todo lo largo de su devenir, constatará su presencia como forjadoras de la nación. Integrante fundamental de la sociedad, la mujer hizo suyas las ansias libertadoras y desempeñó un rol importante en aras de crear una patria común. Se trata de entender que en lo más mínimo su papel fue de “retaguardia”, sino todo lo contrario, su trabajo fue necesario y en no pocas ocasiones empuñó las armas y con valentía gritó ¡viva Cuba libre!, incluso a cambio de su vida, como lo protagonizó la tunera Mercedes Varona. El ejemplo de la mujer cubana y particularmente tunera, es imperecedero en su doble función de ser social y generadora de nuevas vidas, con amplias posibilidades de realización personal y profesional luego de 1959. Su actuación se manifiesta en cada actividad del sector de la salud pública como médica, enfermera, técnica, profesora y estomatóloga, así como también en otros puestos de trabajo no menos necesarios. Ellas con altruismo, solidaridad, responsabilidad y humanismo, son continuadoras de las mejores tradiciones científicas, patrióticas y revolucionarias de nuestro pueblo. Esta edición se dedica al 8 de marzo, día internacional de la mujer, las homenajeamos y recordamos la obra de Laura Martínez Carvajal, primera médica cubana, quien desafió los prejuicios de su época o Isabel Rubio que puso sus conocimientos de medicina farmacéutica al servicio del Ejército Libertador, en el que alcanzó los grados de capitana de sanidad; por citar dos entre las grandes. Otras féminas de la localidad ejercieron en la manigua sus dotes de parteras o enfermeras, tal el caso de Anita Cruz, magnífica artillera, quien estuvo al frente de un hospital de campaña durante la guerra. Allí curó heridas, infecciones, disenter

  8. Epidemia de hepatite veiculada por gamaglobulina contaminada

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    Anastácio Ferreira Morgado

    1982-12-01

    gamaglobulina foram testadas, em laboratórios de referência da Organização Mundial de Saúde, encontrando-se o Ag HB em seis (54,5%J. Os autores concluem que houve alguma falha grave no processo de preparo da gamaglobulina em apreço. E por isto deve-se ter reservas quanto á noção difundida de que esse medicamento está isento do risco de transmitir o vírus hepatite.

  9. Mortalidad por tumores en Santander, 1998-2006

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    Laura Andrea Rodríguez Villamizar

    2008-07-01

    Full Text Available Objetivo: Describir la mortalidad por tumores en el departamento de Santander, Colombia, en el período comprendido entre 1998 y 2006. Métodos: Estudio descriptivo, longitudinal de recolección retrospectiva basado en registros oficiales nacionales. Se realizó análisis de mortalidad por sexo, edad, zona de residencia y tipo de tumor. Resultados:Se registró un total de 13,219 defunciones, con una tasa promedio anual de 76.2 casos por 100,000 habitantes; lastasas más altas se presentaron a partir del año 2002. Elriesgo de morir fue 5% superior en los hombres, exceptoentre los de 25 y 54 años, donde fue superior en las mujeres.El tumor maligno de estómago fue el más frecuente como causa de muerte (tasa mediana 11.8 por 100,000 habitantes. En las mujeres este tumor fue seguido por los tumores malignos de mama y cuello de útero, con tasas medianas de 8.1 y 7.7 por 100,000 habitantes, mientras que en los hombres por los tumores malignos de próstata y debronquios y pulmón, con tasas medianas de 10.7 y 8.3 casos por 100,000 habitantes. Conclusiones: La mortalidad por tumores en Santander constituye la segunda causa de muerte y lleva a fortalecer el diagnóstico temprano de esta enfermedad y de las estrategias poblacionales dirigidas al control de los factores de riesgo.

  10. Impacto do manejo da água na toxidez por ferro no arroz irrigado por alagamento

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    Fabiana Schmidt

    2013-10-01

    Full Text Available A toxidez por ferro é o distúrbio nutricional de maior ocorrência em arroz (Oryza sativa L. cultivado em sistemas alagados, derivada da quantidade excessiva de íons ferrosos (Fe2+ gerados pela redução de óxidos de ferro em solos alagados. Em experimento conduzido em casa de vegetação, foram avaliados os efeitos de manejos da água de irrigação na dinâmica de redução de um Planossolo e na manifestação da toxidez por ferro em arroz. Os tratamentos dispostos em blocos completos ao acaso com quatro repetições constaram de cinco manejos da água: T1- início do alagamento no estádio V2-V3 do arroz; T2- início do alagamento no estádio V6-V7; T3- T1 e drenagem no estádio V10-V11; T4- T2 e drenagem no estádio V10-V11; e T5- T1 e drenagens nos estádios V7-V8 e V10-V11. O atraso do início do alagamento para o estádio V6-V7 do arroz manteve os valores do Eh da solução do solo mais elevados, promovendo menor disponibilidade de Fe2+ na solução do solo e deslocando a máxima liberação de Fe2+ na solução do solo para estádios fenológicos mais avançados do arroz. A realização de drenagens ao longo do ciclo vegetativo do arroz promoveu a reoxidação do solo, que ocasionou o aumento dos valores de Eh e redução da concentração de Fe2+ na solução do solo. O uso de drenagens durante o período vegetativo do arroz foi eficiente no controle da toxidez por excesso de ferro, em arroz cultivado em solo alagado.

  11. El tiempo libre y ocio reivindicado por los trabajadores

    OpenAIRE

    Guillermo Miranda Román

    2006-01-01

    Estas líneas están referidas a la realización de actividades del ocio en el tiempo libre que como derecho ha sido logrado por las luchas de aquellas sociedades cuyo desarrollo industrial y comercial es caracterizado por la designación de tiempos para la producción o distribución de las mercancías. Los trabajadores históricamente han luchado por el derecho a un tiempo libre necesario para el desarrollo de las aptitudes del hombre, asunto que tratamos de discurrir, o en el mejor de ...

  12. Topoplastia de Cvintal assistida por laser de femtossegundo

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    Alexandre Takayoshi Ishizaki

    2013-06-01

    Full Text Available Apresentamos um relato de astigmatismo tardio progressivo pós-transplante de córnea para ceratocone, associado à afinamento periférico na junção doador-receptor, o que presumidamente pode ser considerado como recorrência da ectasia. O caso foi tratado por meio de Topoplastia de Cvintal assistida por laser de femtossegundo para a confecção da incisão com geometria "top hat", seguido de sutura com ajuste per-operatório guiado por ceratoscopia.

  13. La responsabilidad del Estado por la actividad del legislador

    OpenAIRE

    María Consuelo Alonso García; Eric Leiva Ramírez

    2012-01-01

    Analizar el fenómeno de la responsabilidad del Estado causada por los hechos del legislador ha sido un trabajo desarrollado tanto por la doctrina y la jurisprudencia internacional a mediados del siglo xx. En Francia, por ejemplo, se presentó el primer antecedente jurisprudencial en el año de 1934. En España, su estudio empezó a gestionarse con la promulgación de la Constitución de 1978, presentándose el primer fallo judicial en el año de 1993. Para el caso colombiano, la Constitución de 1991 ...

  14. Perforación intestinal por un palillo de dientes

    OpenAIRE

    Marvin Yglesias-Rosales; Andrea Medina-Méndez; Andrea Rodríguez-González

    2006-01-01

    Existe una gran variedad de cuerpos extraños que son deglutidos por los seres humanos, entre los cuales son numerosos los que pueden producir una perforación del tracto gastrointestinal. Se enfocará esta discusión en los palillos de dientes, caso particular, por poseer 2 extremos puntiagudos, lo que hace se consideren como portadores de una gran morbimortalidad. El espectro de manifestaciones clínicas asociado con las lesiones por palillos de dientes ingeridos es muy amplio; el diagnóstico de...

  15. El aprendizaje por indagación I.

    OpenAIRE

    Gómez Martín, Francisco

    2013-01-01

    Este artículo explora cómo se puede usar el aprendizaje por indagación en la enseñanza de las matemáticas. En las matemáticas hace años que se emplea bajo múltiples formas: aprendizaje por resolución de problemas, el método Moore, aprendizaje por proyectos, aprendizaje orientado al proceso, entre otros. En la música, a la luz de nuestro más leal conocimiento, parece que apenas está implantado.

  16. Selección de Recursos Humanos por Competencias

    OpenAIRE

    Sánchez Domingo, Cristina

    2013-01-01

    Los objetivos de este trabajo son, por un lado conocer en qué consisten los procesos de valoración y selección de personas desde el enfoque de las competencias laborales. Para ello, ha sido preciso profundizar en el estudio del concepto de “competencia laboral”, y comprender qué es la Gestión de Recursos Humanos por Competencias, en cuyo seno se encuentra la propia Selección de Recursos Humanos. Por otra parte, un segundo objetivo del trabajo es conocer el grado de implantación de la Selecció...

  17. Aprendizaje por refuerzo en espacios de estados continuos

    OpenAIRE

    Fernández Rebollo, Fernando

    2002-01-01

    El aprendizaje por refuerzo es un modelo de aprendizaje que permite implementar comportamientos inteligentes de forma automática. La mayor parte de la teoría del aprendizaje por refuerzo tiene su fundamento en la programación dinámica, y por tanto, en lo que se denominan funciones de valor. Sin embargo, la implementación tradicional de estas funciones en forma tabular no es práctica cuando el espacio de estados es muy grande, o incluso infinito. Cuando se produce esta situación, se deben apli...

  18. El tiempo libre y ocio reivindicado por los trabajadores

    Directory of Open Access Journals (Sweden)

    Guillermo Miranda Román

    2006-01-01

    Full Text Available Estas líneas están referidas a la realización de actividades del ocio en el tiempo libre que como derecho ha sido logrado por las luchas de aquellas sociedades cuyo desarrollo industrial y comercial es caracterizado por la designación de tiempos para la producción o distribución de las mercancías. Los trabajadores históricamente han luchado por el derecho a un tiempo libre necesario para el desarrollo de las aptitudes del hombre, asunto que tratamos de discurrir, o en el mejor de los casos, reflexionar.

  19. Ansiedad percibida por los pacientes hospitalizados por quemaduras, en una Unidad de Quemados

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    M. Alcázar-Gabás

    2014-06-01

    Full Text Available El presente trabajo, pretende describir el estado de ansiedad que experimentan los pacientes ingresados en una Unidad de Quemados. Uno de los factores clave en los cuidados del paciente quemado es una buena atención psicológica. La realidad demuestra que es el profesional de enfermería quien observa los síntomas emocionales durante los primeros días de ingreso y trata de responder a esa demanda de cuidado. Pretendemos, a través de la medición del nivel de ansiedad que perciben los pacientes ingresados en la Unidad de Quemados elegida para nuestro estudio durante el primer semestre del año 2009, identificar a aquellos que estén en riesgo de padecer mayores niveles de ansiedad durante su hospitalización, para así poder establecer un plan de cuidados adaptado a las necesidades emocionales de cada uno. Los resultados obtenidos nos permiten concluir que los pacientes quemados ingresados en la Unidad de Quemados presentaron niveles elevados de ansiedad que son superiores entre la población femenina, así como en aquellos pacientes con lesiones de mayor extensión. Determinamos también que los pacientes ingresados por quemaduras en la Unidad de Quemados a estudio fueron mayoritariamente varones, de nacionalidad española, residentes en medio urbano con una media de edad de 50 años, siendo las quemaduras producidas por llama en accidentes domésticos la causa más frecuente.

  20. LOGROS DEL FITOMEJORAMIENTO PARTICIPATIVO EVALUADO POR LOS PRODUCTORES INVOLUCRADOS

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    R. Ortiz

    2009-01-01

    un importante empoderamiento del campesino y un aumento significativo de la autoestima del campesino y su familia. Por último, se denotó un efecto de esta estrategia de mejoramiento en la innovación local.

  1. Miíase por Lucilia eximia (Diptera: Calliphoridae em Didelphis albiventris (Mammalia: Didelphidae no Brasil Central

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    Edison Cansi

    2011-12-01

    Abstract. In May 2009 were collected 18 larvae of Lucilia eximia (Wiedemann, a fly responsible for primary and secondary myiasis in livestock and humans. The larvae were taken from the myiasis on anal and auricular regions of an opossum Didelphis albiventris (Lund, in Brasília Zoo, and later identified in the laboratory. After 15 days, 15 adults emerged from L. eximia. This is the first record of this blowfly causing a primary myiasis in a marsupial species in the Brasília Cerrado.

  2. Limitado por lo políticamente correcto.

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    Juan Carlos Ceballos Salgado

    2005-01-01

    Full Text Available He comenzado a sentirme limitado por tanta correctividad política que se nos ha impuesto tanto por el ala derecha como la izquierda. Ambas partes constantemente intentan infringir nuestra libertad diciéndonos que podemos o no podemos, decir o hacer. Me estoy hartando de esto. A continuación algunos ejemplos acerca de lo que están tratando de imponernos.

  3. Secagem por spray: uma revisão

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    Arlan Caldas Pereira Silveira

    2013-04-01

    Full Text Available O objetivo deste artigo foi apresentar os princípios da secagem por spray e os mais recentes resultados de pesquisas na área de leite e derivados. Visando abranger este assunto, o artigo foi dividido em seis partes: introdução, princípios da secagem por spray, atomização, secagem em estágios, resultados de pesquisas e conclusão.

  4. 有氧运动结合耳穴贴压法对医学生失眠干预效果研究%The Effect of Aerobic Exercise Comibined with Auricular Point Therapy on Insomnia of Medical College Students in Tangshan

    Institute of Scientific and Technical Information of China (English)

    尹辉

    2011-01-01

    目的 寻求一种简便有效方法,为防治医学生失眠提供有效数据和理论支持.方法 2007年3月-2009年5月,以随机整群抽样的方法,用匹兹堡睡眠质量指数(PSQI)评价华北煤炭医学院985名学生的睡眠状况,从睡眠差的147人中随机抽取120人为干预对象.随机分为4个组,Ⅰ组进行有氧运动练习,注重运动强度的控制;Ⅱ组实施耳穴贴压治疗,坚持按揉次数;Ⅲ组有氧运动练习的同时耳穴贴压治疗;Ⅳ组为对照组不予干预.比较不同方法对医学生失眠的干预效果.结果 干预4周后,对4个组进行PSQI问卷测试,Ⅰ、Ⅱ、Ⅲ、Ⅳ组PSQI总分分别为6.83±1.27、6.52±1.28、6.00±1.25、9.17±1.27,Ⅰ、Ⅱ、Ⅲ组分别与Ⅳ组比较,PSQI总分差异均有统计学意义(P<0.05或P<0.001).Ⅲ组与Ⅰ组或Ⅱ组比较,PSQI总分、入睡时间、日间功能差异均有统计学意义(P<0.05).干预结束3个月后再次对Ⅰ、Ⅱ、Ⅲ组进行PSQI问卷测试,PSQI各成分与干预结束时的结果相比较,无统计学意义.结论 有氧运动结合耳穴贴压的方法,对改善医学生失眠具有较好效果,特别是对入睡时间、日间功能的改善.%Objective To study the effect of aerobic exercise combined with auricular point therapy on insomnia among medical college students in Tangshan. Methods From March 2007 to May 2009 and using random cluster sampling method, 985 students of a medical college in Tangshan were evaluated with the sleep quality index of Pittsburgh (PSQI). Of 147 students suffered with sleep problem, 120 students were randomly selected as intervention objects and randomly divided into four groups:group Ⅰ, taking the aerobic exercise training and paid more attention to the control of their exercise intensity; group Ⅱ, taking auricular point therapy with confirmed times; group Ⅲ, taking aerobic exercise plus auricular point therapy; and group Ⅳ, as control with no intervention. The effects of 4 groups

  5. The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit.

    Science.gov (United States)

    Vincent, Maxence S; Durand, Eric; Cascales, Eric

    2016-01-01

    The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN, and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we demonstrate that PorX does not bind T9SS gene promoters and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS.

  6. The PorX response regulator of the Porphyromonas gingivalis PorXY two-component system does not directly regulate the Type IX secretion genes but binds the PorL subunit.

    Directory of Open Access Journals (Sweden)

    Maxence S Vincent

    2016-08-01

    Full Text Available The Type IX secretion system (T9SS is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion of surface attachment of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY and PorX encode typical two-component system (TCS sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of the porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we showed that PorX does not bind and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS.

  7. The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit

    Science.gov (United States)

    Vincent, Maxence S.; Durand, Eric; Cascales, Eric

    2016-01-01

    The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN, and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we demonstrate that PorX does not bind T9SS gene promoters and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS.

  8. The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit.

    Science.gov (United States)

    Vincent, Maxence S; Durand, Eric; Cascales, Eric

    2016-01-01

    The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN, and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we demonstrate that PorX does not bind T9SS gene promoters and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS. PMID:27630829

  9. Suicidio por arma de fuego Suicide by firearm

    Directory of Open Access Journals (Sweden)

    M. Soriano Maldonado

    2005-01-01

    Full Text Available El mecanismo elegido para cometer el suicidio depende de numerosos factores personales y sociales. En este número presentamos una imagen del tipo de suicidio más mediático, aunque no por ello el más frecuente en nuestro medio. La variabilidad en la forma de los orificios de entrada y salida por arma de fuego depende de la distancia, tipo de arma y región anatómica por lo que puede presentar una morfología muy variada. Es por ello que, aunque ya se han publicado varias imágenes de suicidio por otro tipo de armas, aportamos un caso de suicidio típico por arma corta con especial descripción de las lesiones que se originan en cráneo.The mechanism chosen for suicide depends upon various personal and social factors. In this paper, we present an image of the more mediatic type suicide, although not the most frequent in our means. The variability in the entrance and exit orifices by firearm depends on the distance, type of weapon and anatomical region; for that reason they can present/display a wide morphology. Although several images of suicide by another type of arms have been published already, today we contributed with a case of typical suicide by handgun, paying special attention to the injuries affecting the skull.

  10. Pronóstico de la diarrea por rotavirus

    Directory of Open Access Journals (Sweden)

    Mota-Hernández Felipe

    2001-01-01

    Full Text Available Objetivo. Comparar la gravedad de la diarrea por rotavirus (RV y por no rotavirus. Material y métodos. Estudio transversal en 520 lactantes con diarrea aguda, efectuado entre octubre de 1994 y marzo de 1995 en siete centros del primer nivel de atención en cinco estados de México. El diagnóstico de RV se realizó con ensayo inmunoenzimático o por electroforesis. El análisis se hizo a través de medidas de tendencia central. Los resultados se presentan como promedio y desviación estándar o mediana o variación. Resultados. Se aisló RV en 264 lactantes (50.7% con predominio en varones de 6 meses a un año. Las manifestaciones clínicas fueron significativamente diferentes entre el grupo rotavirus positivo y el grupo rotavirus negativo en mediana de evacuaciones por 24 horas, frecuencia de vómitos, temperatura > 38° C, deshidratación y calificación de gravedad, respectivamente. Conclusiones. Estos resultados mostraron peor pronóstico por mayor gravedad de la diarrea por RV en lactantes, con relación a otra etiología. El texto completo en inglés de este artículo está disponible en: http://www.insp.mx/salud/index.html

  11. Neuropatia experimental por DDT: análise de nervo por microdissecção de fibras

    OpenAIRE

    Edison Matos Nóvak; Lineu Cesar Werneck

    1984-01-01

    Estudou-se o nervo gênito-femural do rato albino submetido a intoxicação crônica por DDT, administrado por 180 dias na dose de 5 mg/kg de peso via oral. Os resultados mostraram proporção anormal de fibras tipo C, sendo sugerido ocorrer degeneração tipo axonal determinada pelo DDT.

  12. Neuropatia experimental por DDT: análise de nervo por microdissecção de fibras

    Directory of Open Access Journals (Sweden)

    Edison Matos Nóvak

    1984-09-01

    Full Text Available Estudou-se o nervo gênito-femural do rato albino submetido a intoxicação crônica por DDT, administrado por 180 dias na dose de 5 mg/kg de peso via oral. Os resultados mostraram proporção anormal de fibras tipo C, sendo sugerido ocorrer degeneração tipo axonal determinada pelo DDT.

  13. Enxertia em figueira 'Roxo de Valinhos' por borbulhia e garfagem

    Directory of Open Access Journals (Sweden)

    Tailene Elisa Kotz

    2011-01-01

    Full Text Available Com o intuito de desenvolver um protocolo de enxertia em estacas não enraizadas de figueira 'Roxo de Valinhos' (Ficus carica L., foram realizados dois experimentos com aplicação de duas técnicas de propagação: borbulhia e garfagem. No primeiro experimento, estacas lenhosas de 20 cm de comprimento, coletadas da porção mediana dos ramos, de junho a setembro, foram enxertadas por borbulhia tipo placa e "T" normal. No segundo experimento, os propágulos foram coletados em julho e as estacas foram enxertadas pelo método da garfagem, imergindo-se metade das estacas em solução de 2.000 mg L-1 de AIB por 10 segundos e metade permaneceu como controle. Os enxertos foram protegidos com sacos plásticos transparentes (18 x 3 cm, mantidos por 0, 15, 30, 45 e 60 dias. Posteriormente, as estacas dos dois experimentos foram enterradas a 2/3 de seu comprimento em leito de areia, sob telado (sombrite com 50% de luminosidade. Aos 60 e 120 dias após a enxertia, mensuraram-se a porcentagem de borbulhas e garfos vivos, a porcentagem de borbulhas e garfos brotados, a porcentagem de borbulhas e garfos vivos em porta-enxertos enraizados e o comprimento médio da brotação do enxerto. Concluiu-se que a enxertia da figueira 'Roxo de Valinhos' pode ser efetuada por borbulhia, pelo método "T", e por garfagem, devendo-se efetuar a imersão das estacas em AIB e proteger os garfos por 60 dias.

  14. La responsabilidad del Estado por la actividad del legislador

    Directory of Open Access Journals (Sweden)

    María Consuelo Alonso García

    2012-12-01

    Full Text Available Analizar el fenómeno de la responsabilidad del Estado causada por los hechos del legislador ha sido un trabajo desarrollado tanto por la doctrina y la jurisprudencia internacional a mediados del siglo xx. En Francia, por ejemplo, se presentó el primer antecedente jurisprudencial en el año de 1934. En España, su estudio empezó a gestionarse con la promulgación de la Constitución de 1978, presentándose el primer fallo judicial en el año de 1993. Para el caso colombiano, la Constitución de 1991 introdujo en su artículo 90 el fundamento constitucional de la responsabilidad patrimonial del Estado, sin que esto significase que la jurisprudencia del Consejo de Estado encontrase las bases de esta responsabilidad en diferentes disposiciones de la Constitución. Sin embargo, los primeros fallos relacionados con este título de imputación en Colombia fueron emitidos por el máximo tribunal de lo contencioso administrativo en 1998, y por la Corte Constitucional a través de la sentencia C-038 de 2006, providencia judicial que estableció algunas de las características que posee esta figura jurídica.

  15. Riesgos antrópicos generados por la actividad minera

    Directory of Open Access Journals (Sweden)

    Ana Violeta Argüello Mejía

    2013-10-01

    Full Text Available Las actividades productivas generan riesgos antrópicos [1] a mediano y largo plazo. La zona de estudio se ubica en las Parroquias de Pomasqui, San Antonio y Calacalí, donde se han producido riesgos debido a las actividades humanas, en este caso, por la explotación de las canteras para abastecer el mercado de la construcción del Distrito Metropolitano de Quito. La investigación propone determinar los riesgos antrópicos generados por la actividad minera. Los pobladores de la zona identifican que la minería artesanal en sus inicios constituyó una fuente de trabajo, donde sus familias también se involucraban. Actualmente, se observa que en la mayoría de las canteras se utiliza maquinaria especializada y no participan los trabajadores de la zona. Los taludes de las canteras son de 80o y 90o grados, generando amenazas para los trabajadores y moradores de las viviendas aledañas. Uno de los mayores impactos es la contaminación del aire, sin embargo, el suelo y los cursos de agua están siendo afectados por los desperdicios que produce la actividad minera. La población, que está expuesta permanentemente al polvo ocasionado por las canteras y al transporte de material, acusa enfermedades de tipo respiratorio. Así mismo, el ruido ocasionado por el transporte constituye una molestia constante para los pobladores.

  16. Micetoma pulmonar por Scedosporium sp, reporte de dos casos

    Directory of Open Access Journals (Sweden)

    José G. Somocurcio

    2009-07-01

    Full Text Available Se reporta los dos primeros casos de micetoma pulmonar por Scedosporium sp, en el Perú, tratados quirúrgicamente en el Hospital Nacional Hipólito Unanue. Se practicó resección pulmonar debido a micetoma pulmonar de donde se tomó muestras que fueron enviadas a microbiología y anatomía patológica para cultivo y estudio histopatológico. Se identificó el moho Scedosporium sp en dos pacientes con secuelas cavitarias por tuberculosis, quienes presentaron tos y hemoptisis de dos meses y tres años de evolución, respectivamente. Radiológicamente las cavidades estaban ocupadas por una "bola fúngica". La histopatología indicó presencia de abundantes hifas, indistinguibles de las de Aspergillus sp, mientras que la inmunodifusión para Aspergillus fue negativa.

  17. Responsabilidad del empleador por accidentes de trabajo y enfermedades profesionales

    Directory of Open Access Journals (Sweden)

    Cristina Mangarelli

    2014-01-01

    Full Text Available Introducción. 1. Responsabilidad del “empleador” por accidentes de trabajo y enfermedades profesionales. Noción. 2. La indemnización “tarifada”. Fundamento de su procedencia 3. Responsabilidad del empleador por accidentes de trabajo o enfermedades profesionales en la ley uruguaya (ley Nº 16.074. 4. La “ampliación” de la responsabilidad del empleador por el derecho común en el derecho uruguayo (artículo 7 ley Nº 16.074. 5. Requisitos para la ampliación de la responsabilidad patronal: culpa grave en el incumplimientode normas de seguridad y prevención. 6. La culpa grave. Concepto. 7. El modelo del hombre a tener en cuenta en la “culpa grave” no es el del buen padre de familia. 8. El grado de la culpa no puede ser medido por el resultado del accidente. 9. Se aplican las eximentes de la responsabilidad civil. 10. Distintos ámbitos de la responsabilidad patronal por accidentes de trabajo o enfermedades profesionales: A ante la víctima o los derecho-habientes; B ante el Banco de Seguros del Estado; C ante el Ministerio de Trabajo ySeguridad Social. 11. Recupero del BSE en caso de culpa grave en el incumplimiento de normas de seguridad y prevención. Requisitos 12. Responsabilidad del empleador en caso de accidente de trabajo o enfermedad profesional sufrido por un adolescente. Conclusiones.

  18. La responsabilidad del Estado por el hecho del legislador

    Directory of Open Access Journals (Sweden)

    María Consuelo Alonso

    2011-12-01

    Full Text Available Analizar el fenómeno de la responsabilidad del Estado causada por los hechos del legislador ha sido un trabajo desarrollado tanto por la doctrina como por la jurisprudencia internacional a mediados del siglo xx. En Francia, por ejemplo, se presentó el primer antecedentejurisprudencial en el año de 1934. En España, su estudio empezó a gestionarse con la promulgación de la Constitución de 1978, dándose el primer fallo judicial en el año de 1993. Para el caso colombiano, la Constitución de 1991 introdujo en su artículo 90 el fundamento constitucional de la responsabilidad patrimonial del Estado, sinque esto significase que la jurisprudencia del Consejo de Estado encontrase las bases de esta responsabilidad en diferentes disposiciones de la Constitución de 1886, tales como los artículos 2º, 16 y 30, que consagró el principio de legalidad del Estado para proteger la vida, honra y bienes de los ciudadanos, y garantizar la propiedad privada y los demás derechos adquiridos con el título de derecho. Sin embargo, los primeros fallos relacionados con este título de imputación en Colombia fueron emitidos por el máximo Tribunal de lo Contencioso Administrativo colombiano en el año de 1998 y por la Corte Constitucional a través de la Sentencia C-038 de 2006, providencia judicial que estableció algunas de las características que posee esta figura jurídica.

  19. Varmetransport i evakuerede porøse materialer

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe

    Indlægget omhandlede varmetransport i porøse materialer (ledning, konvektion og stråling) under atmosfæretryk og under vacuum. Specielt omhandlede præsentationen også silica aerogel som et eksempel på et højporøst isoleringsmateriale.......Indlægget omhandlede varmetransport i porøse materialer (ledning, konvektion og stråling) under atmosfæretryk og under vacuum. Specielt omhandlede præsentationen også silica aerogel som et eksempel på et højporøst isoleringsmateriale....

  20. Neumonitis por hipersensibilidad en la ciudad de México

    Directory of Open Access Journals (Sweden)

    Carrillo-Rodríguez José G.

    2000-01-01

    Full Text Available OBJETIVO: Determinar la asociación entre la zona urbana de origen del paciente en la ciudad de México y la prevalencia de neumonitis por hipersensibilidad inducida por antígeno aviario. MATERIAL Y MÉTODOS: Se trata de un estudio de casos y controles realizado en el Instituto Nacional de Enfermedades Respiratorias, en la ciudad de México, en el año de 1999. Se estudiaron 109 casos con neumonitis por hipersensibilidad y 184 controles: de éstos, 39, con fibrosis pulmonar idiopática; 63, con tuberculosis pulmonar, y 82, con asma. La ciudad de México y las zonas conurbadas se dividieron en cinco zonas geográficas: centro, noreste, sureste, noroeste y el suroeste. Se calcularon las prevalencias de las diferentes enfermedades por zona urbana de los pacientes que participaron en el estudio; como medida de asociación, se estimó la razón de momios, con un intervalo de confianza al 95%. Asimismo, se realizó regresión logística múltiple ajustando por edad, sexo y estrato socioeconómico. RESULTADOS: Ochenta casos de neumonitis por hipersensibilidad se concentraron en el sur del noreste de las zonas conurbadas y la parte norte del sureste de la ciudad de México, 48 y 32, respectivamente (RM= 3.86, IC 95% 2.17-6.96. Treinta y seis controles de asma se localizaron en el suroeste de la ciudad de México, zona donde se ubica el Intituto Nacional de Enfermedades Respiratorias (p<0.05 y cuatro en la zona conurbada. Los controles de tuberculosis pulmonar y fibrosis pulmonar idiopática estuvieron dispersos en la ciudad de México y en las zonas conurbadas. CONCLUSIONES: La zona sur del noreste y el norte de la sureste están asociadas a la neumonitis por hipersensibilidad. Las causas de esta asociación no parece ser geográfica, pero existe el antecedente de que esa zona fue basurero de la ciudad, por lo que partículas orgánicas en el ambiente pudieran coadyuvar a la aparición de esta enfermedad.

  1. Efecto de la quercetina sobre la nefrotoxicidad producida por cadmio

    OpenAIRE

    A. I. Morales Martín; Vicente Sánchez; C. Santiago Sandoval; J Mª Fernández Tagarro; J.M. López Novoa; F. Pérez Barriocanal

    2004-01-01

    El incremento en la producción anual de cadmio ha favorecido que la incidencia de la intoxicación crónica por este elemento haya aumentado en los últimos años. El estrés oxidativo es uno de los mecanismos implicados en la generación del efecto tóxico, manifestándose, entre otras patologías, por una disfunción y lesión renal. La quercetina, un flavonoide muy abundante en la dieta mediterránea, es un potente antioxidante y un buen quelante de metales. Nuestro objetivo fue estudia...

  2. As comunidades de Porífera do litoral Norte

    OpenAIRE

    Pereira, Tânia Ribeiro

    2007-01-01

    Os indivíduos do filo Porifera possuem um papel essencial nas comunidades bentónicas, não só por serem animais filtradores e detritívoros, como pelo facto de estabelecerem relações simbióticas com vários organismos, nomeadamente algas, e servirem de abrigo e alimento a muitos animais. A estrutura das comunidades Porifera é influenciada por vários factores ambientais, entre os quais os padrões de sedimentação, a velocidade da corrente, e o tamanho e inclinação do substrato. D...

  3. Mujeres procesadas por el Tribunal del Santo Oficio de Granada

    OpenAIRE

    Pérez de Colosía Rodríguez, María Isabel

    2005-01-01

    Actualmente, la Historiografía se ha visto enriquecida gracias a los estudios realizados acerca de las mujeres. Muchos son los aspectos que pueden tratarse al respecto, dada la abundancia de fuentes. En la documentación inquisitorial encontramos un rico filón relativo al tema, que presenta dos aspectos bien diferenciados. Por un lado tenemos a las familiares del personal civil del Santo Oficio, que gozaban de una serie de privilegios. Por otro están aquellas que sufrieron las p...

  4. Infecciones por adenovirus en Cuba (2000-2008)

    OpenAIRE

    González Muñoz, Grehete

    2013-01-01

    Las infecciones por adenovirus causan un variado espectro clínico en el hombre, con un rango que incluye desde la infección asintomática hasta la enfermedad diseminada con peligro para la vida. En el presente estudio, se analizó el comportamiento de las infecciones por adenovirus en síndromes de etiología viral como la infección respiratoria aguda, la miocarditis viral, la conjuntivitis hemorrágica y el síndrome neurológico infeccioso. Además, se estudió la participación de estos agentes en l...

  5. Guía por las lindes transilvanas

    Directory of Open Access Journals (Sweden)

    Rafael Guillermo Serrano

    1998-04-01

    Full Text Available Paul EluardRecorrer ahora el territorio dejado por Bram Stoker y su novela Drácula -a cien años de su primera edición- resulta sin duda caminar por las alucinantes fronteras del mundo delirante del vampiro como el hijo con- sentido de la nocturnidad y de las sombras. Aunque el terreno abonado es significativo, convocamos aquí un breve merodeo en relación con el tema en la literatura y su cuota de realidad; agregamos como postre un grupo de poemas y la conseja para prevenir la visita del vampiro.

  6. La educación por competencias en ciencias naturales

    OpenAIRE

    Mendoza Aguirre, F.; Rodríguez-Pineda, D.

    2009-01-01

    Si bien existen programas de actualización docente, en el ámbito de las Ciencias Naturales dentro de la “Educación por Competencias”, la mayoría de las instituciones que ofrecen capacitación, lo hacen sólo desde el “saber” -conocimiento-, dejando de lado el “saber hacer” y el “saber ser”. El hecho de dejar fuera dos componentes fundamentales de las competencias produce una visión distorsionada en los docentes, la cual hace crisis cuando llegan al aula ha implementar la enseñanza por competenc...

  7. Influence of auricular buried seeds combined with emotional management on bad mood and quality of life of anticipatory nausea and vomiting patients%耳穴埋籽配合情绪管理对预期性恶心呕吐病人不良情绪及生活质量的影响1)

    Institute of Scientific and Technical Information of China (English)

    杜春玲; 王云; 张作芹; 李萍

    2014-01-01

    [目的]探讨耳穴埋籽配合情绪管理对预期性恶心呕吐(ANV)病人不良情绪及生活质量的影响。[方法]将60例发生预期性恶心呕吐病人随机分为干预组与对照组,对照组给予常规护理,干预组在常规护理基础上给予耳穴埋籽及情绪管理。干预前后采用焦虑自评量表(SAS)、抑郁自评量表(SDS)评估病人不良情绪,采用简明健康状况量表评估病人生活质量。[结果]干预后干预组病人 SAS、SDS 评分低于对照组;干预组生理功能、生理职能、躯体疼痛、一般健康状况、精力、社会功能、情感职能评分均高于对照组;恶心呕吐程度轻于对照组。[结论]耳穴埋籽能有效降低病人预期性恶心呕吐的发生程度,缓解病人的不良情绪,提高病人的生活质量。%Obj ective:To probe into influence of auricular buried seeds com-bined with emotional management on negative bad mood and life quality of anticipatory nausea and vomiting(ANV)patients.Methods:A total of 60 ca-ses of patients with anticipatory nausea and vomiting were randomly divided into intervention group and control group,the patients in control group were given routine nursing,the patients in intervention group were given auricular buried seeds combined with emotional management on the basis of conven-tional care.Before and after the intervention,the self rating Anxiety Scale (SAS)and self rating Depression Scale(SDS)were used for assessment of patients with adverse bad mood,the short form health status scale was used to evaluate the quality of life of patients.Results:After intervention,the scores of SAS and SDS of patients in intervention group were lower than those of control group;the scores of physiological function,physiological role,bodily pain,general health,energy,social function,emotional function of the intervention group were higher than those in control group;the degree of nausea and vomiting was lighter than that in control

  8. Signos Vitales de los CDC-Muertes por intoxicación por alcohol (Alcohol Poisoning Deaths)

    Centers for Disease Control (CDC) Podcasts

    2015-01-06

    Este podcast se basa en la edición de enero del 2015 del informe Signos Vitales de los CDC. En los Estados Unidos, mueren en promedio seis personas cada día debido a la intoxicación por alcohol. Infórmese sobre lo que puede hacer para prevenir los atracones de alcohol y las intoxicaciones por alcohol.  Created: 1/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/6/2015.

  9. Levantamiento del proceso de registros contables por causación de las cuentas por cobrar a clientes

    OpenAIRE

    Mayele-Rodríguez, Luz

    2013-01-01

    De igual forma el Proyecto de Mejora de Procesos a elaborar, desarrollar e implementar en el Área Administrativa y Financiera del Centro de Pinturas Automotriz “LMS”, es realizar el levantamiento del Proceso de Registros Contables por Causación de las cuentas por cobrar a clientes. Lo anterior se puede desarrollar a partir de un poder de negociación con proveedores que incluye entre otros los siguientes factores : El plazo alcanzado en la negociación de compras de insumos, materias primas, co...

  10. Exploración dirigida por el objetivo en Aprendizaje por Refuerzo Basado en Modelo para ambientes no estacionarios

    OpenAIRE

    Errecalde, Marcelo Luis; Muchut, Alfredo

    2001-01-01

    El Aprendizaje por Refuerzo Basado en Modelo (ARBM) es una extensión al Aprendizaje por Refuerzo tradicional en la que el agente aprende una política (comportamiento), y en forma simultánea aprende un modelo de su ambiente. Distintos estudios han mostrado la superioridad de los métodos de ARBM sobre los métodos libres de Modelo en ambientes estacionarios. Sin embargo, existen serias dificultades para adaptar los métodos de ARBM a ambientes no estacionarios, existiendo actualmente un único mét...

  11. System design description for portable 1,000 CFM exhauster Skids POR-007/Skid E and POR-008/Skid F

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, O.D.

    1998-07-25

    The primary purpose of the two 1,000 CFM Exhauster Skids, POR-007-SKID E and POR-008-SKID F, is to provide backup to the waste tank primary ventilation systems for tanks 241-C-106 and 241-AY-102, and the AY-102 annulus in the event of a failure during the sluicing of tank 241-C-106 and subsequent transfer of sluiced waste to 241-AY-102. This redundancy is required since both of the tank ventilation systems have been declared as Safety Class systems.

  12. 耳尖放血加耳压治疗瘫痪卧床患者便秘的疗效观察%The curative effect observation of the apex auride bloodletting combined with auricular plaster therapy adopted for constipation of patients with paralysis lying on bed

    Institute of Scientific and Technical Information of China (English)

    相永梅; 刘桂玲

    2001-01-01

    @@Background: The patients with paralysis lying on bed for a long time are easy to constipate,which causes great pain to them,especially the patients with the complications of hypertension、coronary atherosclerotic cardiopathy,inclined to aggravate patients' state of illness even hazard their lives.So it is very important to choose fast and effective ways to resolve the constipation in time. Objective: To observe the curative effect of the apex auride bloodletting combined with auricular plaster therapy adopted for constipation of patients with paralysis lying on bed. Unit:Specialty of Acupuncture and Moxibustion of the General Hospital of Shenyang Military Region. Subject: There were 86 patients of constipation with paralysis lying on bed in this group,male 40 cases,female 46 cases,average ages 65.There were 58 cases in the control group,male 28 cases,femal 30 cases,average ages 63.5.There was statistic comparability on sex,age,course of disease,and so on between the two groups. Design: The patients in the therapeutic group were divided into two dialectical types: the showing of constipation of excess type was: stool had been obstructed for several days,they tried very hard when they were defecating,or fever,excessive thirst,liking cool,reddened tongue,dry rough and yellowish fur,slippery and replete pulse,or disterding pain in hypochondrium and abdomen;the showing of constipation of insufficiency type was: constipation,dim complexion,dizziness and palpitation,fatigue,pale tongue,thin and whitism fur,feeble and thready pulse,or liking warm and fearing cold,pale tongue,deep and slow pulse.Therapy were completed seperately according to the types.

  13. Repair of large tympanic membrane perforation with inner graft using Portmann' s posterior-superior incision retro-auricular approach: a report of 45 cases%Portmann氏耳后上进路全翻内植法修补鼓膜大穿孔45例报告

    Institute of Scientific and Technical Information of China (English)

    董和霞; 王晓辉

    2011-01-01

    目的 探讨Portmann氏耳后上进路全翻内植法修补鼓膜大穿孔的方法及疗效.方法 采用耳后上进路,自体颞肌筋膜作为移植材料,对45例鼓膜大穿孔病人进行全翻外耳道后壁皮瓣鼓膜成形术,并对其临床资料进行回顾性分析.结果 术后6个月随访,43例鼓膜穿孔愈合,2例出现鼓膜中央小穿孔,听力均有不同程度的提高.结论 本术式术野暴露清晰,取颞肌筋膜在同一切口进行,修补鼓膜大穿孔成功率高,具有较高的临床应用价值.%Objective To report techniques and effects of myringoplasty using Portmann' s posterior-superior incision retro-auricular approach with complete tympanic membrane elevation and inner graft for repair large size perforations. Methods Myringoplasty was performed in 45 patients. Following tympanic membrane elevation, temporal fascia was used as the autograft and placed on the inner side. Results Forty-three cases acheieved first stage healing of perforation At six month follow up, the tympanic membrane remained healed in 43 cases and showed small central perforation in 2 cases. Hearing in all patients was improved after operations. Conclusion This operative approach allows clear visualization and harvesting of temporal fascia in the same field. The success rate of repairing large perforation with this technique is higher, deserving extensive use.

  14. Identification of Porphyromonas gingivalis proteins secreted by the Por secretion system.

    Science.gov (United States)

    Sato, Keiko; Yukitake, Hideharu; Narita, Yuka; Shoji, Mikio; Naito, Mariko; Nakayama, Koji

    2013-01-01

    The Gram-negative bacterium Porphyromonas gingivalis possesses a number of potential virulence factors for periodontopathogenicity. In particular, cysteine proteinases named gingipains are of interest given their abilities to degrade host proteins and process other virulence factors such as fimbriae. Gingipains are translocated on the cell surface or into the extracellular milieu by the Por secretion system (PorSS), which consists of a number of membrane or periplasmic proteins including PorK, PorL, PorM, PorN, PorO, PorP, PorQ, PorT, PorU, PorV (PG27, LptO), PorW and Sov. To identify proteins other than gingipains secreted by the PorSS, we compared the proteomes of P. gingivalis strains kgp rgpA rgpB (PorSS-proficient strain) and kgp rgpA rgpB porK (PorSS-deficient strain) using two-dimensional gel electrophoresis and peptide-mass fingerprinting. Sixteen spots representing 10 different proteins were present in the particle-free culture supernatant of the PorSS-proficient strain but were absent or faint in that of the PorSS-deficient strain. These identified proteins possessed the C-terminal domains (CTDs), which had been suggested to form the CTD protein family. These results indicate that the PorSS is used for secretion of a number of proteins other than gingipains and that the CTDs of the proteins are associated with the PorSS-dependent secretion. PMID:23075153

  15. Validade por processo de resposta no teste de Cloze

    Directory of Open Access Journals (Sweden)

    Neide de Brito Cunha

    2009-12-01

    Full Text Available Tendo por base considerações sobre as evidências de validade por processo de resposta, foram analisados neste estudo os erros cometidos num teste de Cloze. Participaram 266 crianças, de ambos os sexos, entre 8 e 13 anos, de terceiras e quartas séries do Ensino Fundamental de escolas públicas e particulares de São Paulo. Foram formados dois grupos de protocolos: das crianças que tiveram as melhores e as piores pontuações, para a construção de uma escala dos tipos de erros cometidos, a saber: branco, fonológico, lexical, sintático e semântico. Os resultados mostraram que as crianças com médias mais altas cometeram mais erros lexicais e as com médias mais baixas, erros semânticos. Embora tenha sido encontrada a evidência de validade por processo de resposta, por meio da avaliação da homogeneidade na distribuição dos tipos de erros, é preciso ampliar o conhecimento sobre as características psicométricas do teste de Cloze.

  16. Enoftalmos unilateral por várice orbitaria

    Directory of Open Access Journals (Sweden)

    Ricardo J. Smith

    2014-04-01

    Full Text Available El enoftalmos es un motivo de consulta poco frecuente en la práctica médica. La mayor parte de los casos se debe a un aumento de la cavidad ósea orbitaria de origen traumático. Presentamos el caso de una mujer de 63 años que consultó por enoftalmos progresivo de su ojo izquierdo, de doce años de evolución. El examen oftalmológico reveló la presencia de un marcado enoftalmos del lado izquierdo, que mejoraba notablemente con maniobras de Valsalva. Una tomografía computarizada y una resonancia magnética de la órbita permitieron diagnosticar una várice orbitaria no complicada. Las várices orbitarias son infrecuentes y por lo general se manifiestan por episodios de exoftalmos intermitente. Sin embargo, en raras ocasiones, la distensión y colapso repetidos pueden llevar a un enoftalmos progresivo por atrofia de la grasa orbitaria.

  17. Centros oncológicos designados por el NCI

    Science.gov (United States)

    El programa de centros oncológicos designados por el Instituto Nacional del Cáncer (NCI) reconoce a los centros de todo el país que cumplen con rigurosos criterios para participar en proyectos avanzados de primer nivel para la investigación multidisciplinaria del cáncer.

  18. Disminuyen en los Estados Unidos las infecciones por VPH.

    Science.gov (United States)

    La infección por los tipos del virus del papiloma humano (VPH) en el blanco de la vacuna cuadrivalente se redujo en casi dos tercios en las adolescentes desde que se recomendó la vacunación en los Estados Unidos.

  19. Muerte cerebral causada por consumo de psicofármacos

    OpenAIRE

    Iglesias Rozas, José Rafael, 1942-

    1987-01-01

    Tres imágenes de una biopsia de un cerebro en estado de muerte cerebral causada por consumo de psicofármacos. Three pictures of a biopsy of a brain that has died because of consumption of psychoactive drugs.

  20. Analisis cualitativo asistido por computadora Computer-assisted qualitative analysis

    Directory of Open Access Journals (Sweden)

    César A. Cisneros Puebla

    2003-01-01

    Full Text Available Los objetivos de este ensayo son: por un lado, presentar una aproximación a la experiencia hispanoamericana en el Análisis Cualitativo Asistido por Computadora (ACAC al agrupar mediante un ejercicio de sistematización los trabajos realizados por diversos colegas provenientes de disciplinas afines. Aunque hubiese querido ser exhaustivo y minucioso, como cualquier intento de sistematización de experiencias, en este ejercicio son notables las ausencias y las omisiones. Introducir algunas reflexiones teóricas en torno al papel del ACAC en el desarrollo de la investigación cualitativa a partir de esa sistematización y con particular énfasis en la producción del dato es, por otro lado, objetivo central de esta primera aproximación.The aims of this article are: on the one hand, to present an approximation to the Hispano-American experience on Computer-Assisted Qualitative Data Analysis (CAQDAS, grouping as a systematization exercise the works carried out by several colleagues from related disciplines. Although attempting to be exhaustive and thorough - as in any attempt at systematizing experiences - this exercise presents clear lacks and omissions. On the other hand, to introduce some theoretical reflections about the role played by CAQDAS in the development of qualitative investigation after that systematization, with a specific focus on data generation.

  1. El dilema del consenso por superposición rawlsiano

    Directory of Open Access Journals (Sweden)

    Vergés Gifra, Joan

    2004-12-01

    Full Text Available In this paper we present an objection against the idea of overlapping consensus, nuclear to John Rawls political liberalism. The objection can be put in a dilemmatic form: either an overlapping consensus plays no significant role when it comes to justify the two principles of the conception of justice as fairness, or such idea presupposes the acceptation of some traits or concepts particular to a comprehensive liberalism.

    En este trabajo presentamos una objeción al liberalismo político de John Rawls. La objeción puede formularse en forma de un dilema que afecta especialmente a la noción de consenso por superposición: o bien el consenso por superposición no ofrece ninguna razón categórica o justificativa a favor de los dos principios de justicia rawlsianos y, por tanto, es irrelevante, o bien tal noción presupone la aceptación de determinados caracteres o conceptos propios de un liberalismo comprehensivo y, por consiguiente, la concepción de la justicia como equidad no es tan política como Rawls sugiere.

  2. Trombocitopenia induzida por heparina Heparin-induced thrombocytopenia

    Directory of Open Access Journals (Sweden)

    Fernanda Longhi

    2001-08-01

    Full Text Available O objetivo deste relato é fazer uma revisão a fim de obter informações atualizadas sobre trombocitopenia induzida por heparina, suas manifestações clínicas, seu diagnóstico e seu manejo terapêutico. Após, concluímos que a trombocitopenia induzida por heparina é uma complicação comum em pacientes submetidos a tratamento com heparina, indiferentemente da doença de base. Complicações trombóticas potencialmente fatais têm sido descritas. Por essa razão, se houver suspeita de trombocitopenia induzida por heparina, uma abordagem adequada incluindo suspensão precoce da heparina é mandatória. Produtos que substituem a heparina incluem hirudina e danaparóide sódico. Heparina de baixo peso molecular é contra-indicada.The aim of this paper is to review current information about the clinical manifestations, diagnosis and management of heparin-induced thrombocytopenia. This was achieved by a bibliographic review using Public Medline and consulting Hematology textbooks. From this study we concluded that heparin-induced thrombocytopenia is a common complication of patients exposed to heparin therapy regardless of underlying conditions. Potentially fatal thrombotic complications have been reported. Therefore, if heparin-induced thrombocytopenia is suspected, an adequate approach including early heparin discontinuation is mandatory. Alternative products for heparin include hirudin and danaparoid sodium. Low-molecular-weight heparin is contraindicated.

  3. Reacciones radicalarias de epoxicetonas insaturadas inducidas por titanoceno

    OpenAIRE

    Mateos Burón, Lydia

    2010-01-01

    [ES]Tesis doctoral sobre Reacciones radicalarias de epoxicetonas insaturadas inducidas por titanoceno, perteneciente al departamento de química orgánica [EN]Doctoral Thesis on the radical reactions induced by unsaturated titanocene epoxicetonas, from the organic chemistry´s departament

  4. Mortalidad por envenenamiento en niños

    Directory of Open Access Journals (Sweden)

    Híjar Martha

    1998-01-01

    Full Text Available Objetivo. Conocer el panorama de las muertes por envenenamiento en niños de 0-14 años ocurridas en la República mexicana, entre 1979 y 1994. Material y métodos. Se utilizaron fuentes secundarias. Las variables analizadas fueron: edad, sexo, año, causa externa de traumatismos y envenenamientos, de la IX Clasificación Internacional de Enfermedades: E850-E858, E860-E869 y E905. Mediante un modelo de regresión Poisson se analizaron tendencias por causa específica y se obtuvieron riesgos relativos según edad, sexo y entidad federativa. Resultados. Hubo un total de 11 272 defunciones en menores de 15 años; las principales causas fueron el envenenamiento y las reacciones tóxicas causadas por plantas y animales venenosos (E905, el envenenamiento accidental por gas de uso doméstico y por monóxido de carbono (E868 y el envenenamiento accidental por otras drogas (E858. El grupo de edad que presentó los mayores riesgos, para las causas mencionadas, fue el de menores de un año con un riesgo relativo (RR de 29.6, IC95% 29.2-33.4; RR 3.47, IC95% 2.86-4.22, y RR 31.86, IC95% 24.8-40.9. El riesgo fue similar en ambos sexos, salvo para la causa E905. El estado de Aguascalientes se situó sistemáticamente entre los de mayor riesgo para todas las causas analizadas, mientras que Nuevo León siempre se ubicó entre los de riesgo más bajo. Conclusiones. El envenenamiento constituye una importante causa de muerte en los niños; el riesgo se incrementa al disminuir la edad. Considerando que esas muertes son potencialmente evitables y que la mayor parte de los envenenamientos ocurren en el hogar, para prevenirlos, se recomienda a los familiares vigilar y mantener fuera de peligro al niño. Por otra parte, la multicausalidad del fenómeno requiere que su prevención se realice desde una perspectiva multidisciplinaria que genere una cultura y un ambiente de seguridad en la sociedad.

  5. Effect evaluation of auricular plaster therapy based on the pattern/syndrome differentiation in patients with constipation induced by strong opioid drugs for pain%耳穴贴压辨证干预强阿片相关性便秘的效果评价

    Institute of Scientific and Technical Information of China (English)

    杨丽华; 段培蓓; 徐亚楠; 侯庆梅; 梅思娟; 王晓庆; 孙龙

    2014-01-01

    Objective To explore the effect of auricular plaster therapy on associated symptoms and quality of life in patients with constipation induced by strong opioid drugs for pain.Methods A total of 60 patients selected were randomly divided into the intervention group and the control group with 30 cases in each group.The intervention group was treated with auriculotherapy based on the pattern/syndrome differentiation after detecting the auricular sensitive acupoints' distribution in patients with opioid-induced constipation after receiving opioid therapy.BFI,self-made scale on symptoms accompanied by constipation and PAC-QOL were used to collect data about constipation symptoms and the level of quality of life before or after the intervention,and still with a subset of the intervention group followed for more than two weeks.Results The BFI and PAC-QOL scores of the intervention and control group were lower after intervention,and the decline score of the two groups showed significant difference.But for the self-made scale,the score of each item was slightly lower compared with that before treatment,which showed no statistically significant difference between groups.A follow-up of 2 weeks showed that the long-term efficacy of auricular plaster therapy was significantly lower than before,but was less desirable than short-term.Conclusions Scientific and reasonable choice of acupoint prescription according to syndrome differentiation can effectively improve symptoms accompanied by constipation and patients' quality of life.%目的 评价耳穴贴压对阿片类便秘患者便秘相关症状和生活质量的影响.方法 将符合纳入、排除标准的60例阿片相关性便秘患者采用随机数字表法分为干预组和对照组(乳果糖)各30例.干预组采用前期探查出的阿片类便秘人群阳性率较高的耳穴点结合辨证取穴进行干预;对照组给予乳果糖口服溶液15 ml/次,3次/d,同时结合便秘常规护理.运用阿片类便秘专用

  6. Effect of Electroacupuncture Stimulation of Auricular Concha Region at Different Time-points on Behavior Changes in Depression Rats%电针耳甲区不同介入时间对抑郁大鼠行为学的影响

    Institute of Scientific and Technical Information of China (English)

    刘儒鹏; 荣培晶; 黄占霞; 贲卉; 李亮; 马慧敏; 马迎歌; 朱兵

    2012-01-01

    Objective To observe the effect of electroacupuncture (EA) stimulation of auricular concha region (ACR) on behavior changes of depression rats. Methods A total of 80 male Wistar rats were randomized into depression modeKmodel, n = 6), EA-ACR(n = 12), preventive EA-ACR(Pre-EA-ACR, n = 1l)and EA-ear-tip(n= 12)groups. Depression model was established by chronic unpredictable mild stress for 21 days and isolated breeding. Open-field test and sucrose solution intake preference test were conducted to assess changes of the rats' behavior activities before modeling and on day 22. 36 and 50 after starting model. For rats of the pre-EA-ACR group, EA (2 Hz, 1 mA) was applied to the bilateral auricular concha area for 20 min, once daily for 14 days, beginning from the 8th day on after starting model preparation till the end of the modeling, and for rats of the EA-ACR and EA-ear-tip groups, EA was given to the bilateral ACR and ear-tips respectively, beginning after modeling, once daily for 14 days. Results In comparison with pre-modeling, the percentages of sucrose solution consumption in rats of the model group decreased gradually from day 22 to 50 (P>0. 05). Compared with the model group,the percentage of sucrose solution consumption in the EA-ACR group was increased significantly on day 50( P0.05). Open-field test showed that in comparison with pre-modeling in the same one group, the total scores, crossing and rearing scores on day 22 were decreased considerably In the model and EA-ear-tip groups (P0. 05), suggesting a suppressing effect of pre-EA-ACR and EA-ACR on depression behavior. Compared to day 22 in the same one group, the total scores, crossing and rearing scores on day 36 and 50 in the pre-EA-ACR and EA-ear-tip groups were decreased significantly (P<0. 05, P<0. 01). Conclusion EA of auricular concha region can restrain the development of depression behavioral status in depression rats .which is superior to that of EA of ear-tip.%目的:观察耳甲部迷走神经

  7. Let ear speak:an auricular frontal-lobe-point's near-infrared spectroscope brain-computer interface%让耳朵说话:基于单通道耳穴近红外谱的脑机接口(英文)

    Institute of Scientific and Technical Information of China (English)

    李文石; 钱重阳; 李雷; 魏锋

    2012-01-01

    基于脑机接口的读心术的本质是神经解码.近期研究关注的脑功能区包括初级视觉区、布罗卡区(语言产生中枢)和威尔尼克区(听性语言理解中枢),然而使用了复杂的功能磁共振成像术和植入电极阵列.为了克服前述的仪器复杂性和植入局限性,我们发展了一种语言中枢解码方法,采用外挂式单通道近红外透射(额耳穴)传感器、示波器与计算机后处理,再现与分析语言中枢(布罗卡区)(默读汉字例如你、我或她、他时)与额耳穴的神经血管耦合联系特征.测量信号波长选自人体生命之窗内的875nm,其响应氧合血红蛋白的吸收率相对敏感,借助耳垂的动脉血氧饱和度高达约90%的原理背景,同时,测试技巧也涉及理解信号的典型延迟期.数据处理的结果表明,一是时域或频域内的汉字识别率可以高达70%(受试者4人),二是在时域特征内分别再现了三个汉字的声母特征(过渡的弱电位)与韵母特征(强直的梭形电位).本工作或可为获得型失语症患者提供利用耳朵说话的语言中枢控制的新的并行信道(相对于从脑到口的语言产生通道),特点是单通道且无损.%Mind reading through brain-computer interface(BCI) is in essence of neural decoding.Recent study cases concern functional areas of the cerebral cortex such as early visual region,Broca's area and Wernicke's area.However these studies typically used complex BCI(for example,fMRI) and implanted multi-channel BCI(for example,implanted electrode arrays).To overcome these limitations,here we develop a decoding method based on out-hanging one-probe Chinese auricular frontal-lobe-point's near infrared spectroscope(NIRS) that characterizes the relationship between silent reading in mind(meditated) isolated Chinese word and auricular frontal-lobe-point's mapping NIRS activity from Broca's area(called speech centre).This method is grasped in

  8. Morbilidad oculta por parasitismo intestinal en Lagunita, municipio Girardot, Venezuela

    Directory of Open Access Journals (Sweden)

    Yanelis Núñez Gómez

    2014-08-01

    Full Text Available Se realizó un estudio epidemiológico descriptivo de corte transversal, con el objetivo de determinar la morbilidad oculta por parasitismo intestinal en Lagunita, municipio Girardot, Venezuela; en el período de enero a octubre de 2009. El universo fue de 286 niños, lo que se corresponde con la población total del grupo de edad de menores de 15 años. De estos se seleccionaron por muestreo aleatorio simple 43 pacientes, a los que se les aplicó un cuestionario y se confeccionó una guía de observación, para describir los factores epidemiológicos que influyen en la infestación por parasitismo intestinal. Además, se les realizaron análisis de las heces fecales seriadas para el diagnóstico del parasitismo. El método estadístico fue el cálculo de las frecuencias absolutas y relativas. A través del estudio de las heces fecales seriadas se obtuvo que 27 pacientes tenían parasitosis intestinal, para una morbilidad de 62,79%, con una mayor incidencia en los niños de cinco a nueve años de edad. El sexo femenino fue el más afectado. Los factores epidemiológicos que más influyeron fueron: los malos hábitos higiénicos personales, el entorno desfavorable y el consumo de agua no potable; existió relación entre el nivel socioeconómico, los factores epidemiológicos y la morbilidad por parasitismo intestinal. Predominó la parasitosis por Entamoeba Histolytica, con 11 casos, para un 40,74%. La diarrea, las molestias abdominales y la pérdida de apetito constituyeron los principales síntomas

  9. LUCHA POR LA TIERRA EN EL NORTE DE URUGUAY

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    Gabriel Oyhantçabal Benelli

    2011-12-01

    Full Text Available Este artículo analiza la trayectoria de la lucha por la tierra en Bella Unión, una región característica en Uruguay por la producción de caña de azúcar, a través de los movimientos de clase de sus principales protagonistas: los cortadores de caña sindicalizados en la Unión de Trabajadores Azucareros de Artigas (UTAA. El recorrido histórico hace énfasis en dos períodos históricos diferentes: 1961-1973 y 2005-presente. El primero va desde la fundación del sindicato hasta el golpe militar. Se da en un contexto de auge de la lucha de masas en Uruguay en el cual los trabajadores rurales se organizan en la UTAA levantando, entre otras, la bandera de la Reforma Agraria. El segundo período está marcado por la llegada al gobierno nacional del Frente Amplio, una coalición social-demócrata que reactiva la producción de caña de azúcar en Bella Unión. Este cambio supone una oportunidad para las luchas sociales que la UTAA aprovecha con ocupaciones de tierra favoreciendo un proceso de colonización para los trabajadores rurales. Sin embargo el acceso a la tierra genera nuevas contradicciones, y por tanto nuevos desafíos, por los cambios en la forma de subsunción del trabajo al capital.

  10. CARACTERÍSTICAS DA VIOLÊNCIA SEXUAL SOFRIDA POR CRIANÇAS ASSISTIDAS POR UM PROGRAMA DE APOIO

    Directory of Open Access Journals (Sweden)

    KELLY LINHARES VASCONCELOS

    2010-01-01

    Full Text Available En Brasil, las estadísticas de la violencia sexual contra niños están lejos de reflejar la verdadera realidad actual debido a la baja notificación de los casos. La finalidad de este estudio fue caracterizar el abuso sexual sufrido por niños asistidos por el Programa Sentinela y el perfil del agresor, en Sobral-Ceará, en el periodo que va del 2002 al 2006. La muestra no probabilística intencional fue compuesta por 50 víctimas de abuso sexual y de las mismas, el 66% es del sexo femenino, con predominio de rango de edad entre 8-12 años incompletos, (58%; en el 36% de los casos los padres están separados, siendo la madre la principal responsable por la familia (62%. La mayoría de los agresores es del sexo masculino (78%. En el ambiente fuera de la familia los agresores son conocidos o amigos de la familia (14%; dentro del seno familiar el padrastro es identificado como siendo el agresor más frecuente (18%. Los datos destacan características similares a las de otros estudios, definiendo una cierta igualdad en este tipo de violencia.

  11. Os desdobramentos internacionais do desenvolvimento e da demanda por petróleo na China, por Diego Pautasso

    OpenAIRE

    DIEGO PAUTASSO

    2009-01-01

    Esteartigoaborda a crescente demanda da
    China por petróleo e seus desdobramentos internacionais.
    O argumento central équea política externa
    e a economia da China têm fornecidoumaresposta
    ativa à dependência de petróleo com consequênciasimportantes
    parao reordenamento mundial.

  12. Vivencias psicosociales reveladas por niños que reciben tratamiento con quimioterapia por cáncer

    Directory of Open Access Journals (Sweden)

    BLANCA CECILIA VANEGAS DE AHOGADO

    2009-12-01

    Full Text Available Se realizó un estudio cualitativo con el propósito de descubrir las vivencias psicosociales de niños y niñas de 9 a 12 años que recibían tratamiento con quimioterapia por cáncer. La recolección de la información se hizo mediante encuentros lúdicos con el apoyo de algunas preguntas básicas que facilitaron las revelaciones narrativas. Tres aspectos se destacan en los hallazgos del estudio: vivencias desfavorables, vivencias relacionadas con la autoestima y vivencias favorables; las dos primeras, de diversa manera, afectan en estos niños su vida personal, familiar, escolar y, en general, todo su entorno. Es de resaltar que, como consecuencia de la caída del cabello, con frecuencia han sido objeto de burla y de rechazo por sus compañeros de estudio, lo que produce el más notorio efecto sobre su autoimagen; por otra parte, el ausentismo escolar conlleva dificultades académicas y sentimientos de tristeza en estos niños, situación que empeora cuando, por motivos de tratamiento, su lugar de residencia está alejado de la ciudad, viéndose sometidos a largos periodos de separación, no solo de su familia sino de sus pares. Se concluye que la mayor parte de las revelaciones son impactantes por su gran contenido de sufrimiento y dolor para estos niños, lo que demuestra la urgencia de retomar los hallazgos del estudio para orientar el cuidado de enfermería de manera más integral y apoyar para que se haga lo propio en el hogar y en las instituciones educativas.

  13. 针叩联合耳针对阴虚夹瘀型肥胖并发高脂血症“脂肪-胰岛内分泌轴”的调节*%Effect of Combined Therapy of Acupuncture, Tapping and Auricular Needling on Fatty-insulin Endocrine Axis in Obesity Complicated with Hyperlipidaemia Patients withYin-deficiency and Blood-stasis Pattern

    Institute of Scientific and Technical Information of China (English)

    王鸣; 刘志诚; 徐斌

    2015-01-01

    目的:观察“针叩联合耳针”对阴虚夹瘀型肥胖并发高脂血症患者“脂肪-胰岛内分泌轴”功能的调节作用。方法:本研究共纳入108例阴虚夹瘀型肥胖并发高脂血症患者,随机分为“针叩联合耳针”组和“针叩”组,各54例。针叩耳针组采用针刺和叩刺联合耳针施治,“针叩组”采用针刺和叩刺联合施治,并与正常组52例患者作对比。观察两组患者治疗前后“脂肪-胰岛内分泌轴”指标、脂质指标、肥胖指标、植物神经功能指数(Y值)的变化和临床减肥降脂疗效。结果:“针叩耳针组”与“针叩组”患者治疗前的肥胖指标、FINS、FPG、Homa-IR、FLP、TG、TC、LDL-C及Y值均显著高于正常组(P<0.01),而HDL-C、ISI却显著低于正常组(P<0.01)。治疗后两组患者均取得了较为满意的减肥和降脂疗效,“脂肪-胰岛内分泌轴”指标(FINS、FPG、Homa-IR、FLP)均显著下降(P<0.05),ISI显著上升(P<0.05)。“针叩联合耳针”组在调整“脂肪-胰岛内分泌轴”水平、血脂水平及植物神经功能水平上的效果显著优于“针叩组”(P<0.05)。结论:阴虚夹瘀型肥胖并发高脂血症患者存在“脂肪-胰岛内分泌轴”功能紊乱,“针叩联合耳针”及“针叩治疗”均对其功能具有良性的调整作用,且“针叩联合耳针”治疗的疗效更显著。%This study was aimed to observe effect of combined therapy of acupuncture, tapping and auricular needling on fatty-insulin endocrine axis in obesity complicated with hyperlipidaemia patients withyin-deficiency and blood-stasis pattern. A total of 108 patients with obesity complicated with hyperlipidaemia ofyin-deficiency and blood-stasis pattern were randomly divided into the treatment group of combined therapy of acupuncture, tapping and auricular needling, and the acupuncture and tapping group, with 54 cases in each group. The

  14. Candida albicans skin abscess Abscesso de pele por Candida albicans

    Directory of Open Access Journals (Sweden)

    Felipe Francisco Tuon

    2006-10-01

    Full Text Available Subcutaneous candidal abscess is a very rare infection even in immunocompromised patients. Some cases are reported when breakdown in the skin occurs, as bacterial cellulites or abscess, iatrogenic procedures, trauma and parenteral substance abuse. We describe a case of Candida albicans subcutaneous abscess without fungemia, which can be associated with central venous catheter.Abscesso subcutâneo por Candida é infecção muito rara mesmo em pacientes imunocomprometidos. Alguns casos são relatados quando ocorre dano na pele, como celulite bacteriana ou abscesso, procedimentos iatrogênicos, trauma e abuso de substância parenteral. Relatamos caso de abscesso subcutâneo por Candida albicans sem fungemia, que pode estar associado com cateter venoso central.

  15. Calidad percibida por el espectador de fútbol

    Directory of Open Access Journals (Sweden)

    Isabel Mar\\u00EDa Rosa D\\u00EDaz

    2012-01-01

    Full Text Available Para lograr competitividad, las organizaciones se esfuerzan por comprender las necesidades de sus clientes, con el fin de satisfacerlas adecuadamente. En esta línea, en el ámbito de la gestión deportiva se ha iniciado un caminocuyo objetivo consiste en crear medidas específicas de la calidad del servicio y la satisfacción del cliente. Este es el contexto en el que se enmarca la presente investigación, cuyo objetivo fundamental consisteen determinar las dimensiones de la calidad del servicio deportivo ofrecido por los clubes de fútbol. Para ello se ha aplicado un cuestionario a través del método de la encuesta personal. Los datos obtenidos han sido tratados mediante un análisis factorial exploratorio. Los resultados permiten identificar diez dimensiones básicas de la calidad del servicio deportivo analizado.

  16. Optimizacion del talento en las organizaciones gestion por expectativas

    OpenAIRE

    Castilla Sánchez, Antonio

    2013-01-01

    La gestión del talento es en la actualidad un ámbito de estudio propio de la dirección de empresas y más concretamente, de las Direcciones de RR.HH, que ha despertado el interés de académicos del ámbito de la psicología de las organizaciones en las últimas décadas. La tesis que se presenta, “optimización del talento en las organizaciones: Gestión por expectativas”, nos ofrece un viaje por la realidad de una organización mediante un estudio etnográfico, llevado a cabo en una empresa de serv...

  17. Neuropatia Óptica Tóxica causada por Dissulfiram

    OpenAIRE

    Lemos, José Alberto; Ribeiro, Isabel; Martins, João; Menezes, Carlos; Gonçalves, Rita; Coelho, Pedro; Maio, Tiago

    2015-01-01

    Objetivos: O dissulfiram é utilizado no tratamento do alcoolismo crónico há mais de 50 anos. Este fármaco interfere no metabolismo do etanol e encoraja a abstinência por causar sintomas desagradáveis com a ingestão concomitante de álcool. Efeitos adversos incluem casos raros de neuropatia óptica bilateral. O objetivo deste artigo é descrever um caso clínico de neuropatia óptica tóxica causada por dissulfiram. Métodos: Descrição do caso clínico e breve revisão bibliográfica. Resultados: Report...

  18. Diagnóstico auxiliado por computador na radiologia

    Directory of Open Access Journals (Sweden)

    Azevedo-Marques Paulo Mazzoncini de

    2001-01-01

    Full Text Available Vários desenvolvimentos tecnológicos estão convergindo de forma a aumentar a influência da área de imagens nas pesquisas biomédicas e na medicina clínica. Muitos pesquisadores têm trabalhado no desenvolvimento de sistemas computadorizados para detecção automatizada e quantificação de anormalidades em imagens radiológicas. Estes sistemas são dedicados ao diagnóstico auxiliado por computador. Este artigo discute os conceitos básicos relacionados ao diagnóstico auxiliado por computador e apresenta uma revisão bibliográfica sobre o assunto.

  19. LUCHA POR LA TIERRA EN EL NORTE DE URUGUAY

    OpenAIRE

    Gabriel Oyhantçabal Benelli; Matías Carámbula Pareja

    2011-01-01

    Este artículo analiza la trayectoria de la lucha por la tierra en Bella Unión, una región característica en Uruguay por la producción de caña de azúcar, a través de los movimientos de clase de sus principales protagonistas: los cortadores de caña sindicalizados en la Unión de Trabajadores Azucareros de Artigas (UTAA). El recorrido histórico hace énfasis en dos períodos históricos diferentes: 1961-1973 y 2005-presente. El primero va desde la fundación del sindicato hasta el golpe militar. Se d...

  20. Hugo Grocio: la guerra por medio del derecho

    Directory of Open Access Journals (Sweden)

    Javier Peña Echeverría

    2014-01-01

    Full Text Available La posición de Grocio respecto a la guerra es considerada en este artículo como un intento de mediación entre el realismo político y el moralismo pacifista. Aunque la guerra es una consecuencia inevitable del conflicto permanente en las relaciones humanas, puede ser ajustada a los principios y reglas del derecho natural común a los hombres y del derecho de gentes resultante del consenso entre los pueblos. En consecuencia, Grocio expone las condiciones de justificación de la guerra y propone reglas de conducta en la guerra. Sin embargo, persiste una tensión insuperable entre las pretensiones normativas de la moral y el derecho, por un lado, y la lógica de la fuerza propia de la guerra, por otro.

  1. El riego por chorro intermitente: un sistema prometedor

    Directory of Open Access Journals (Sweden)

    Hernando Buriticá

    2011-10-01

    Full Text Available A través de la historia el hombre se ha ingeniado varios sistemas para suplir las deficiencias de agua que las condiciones naturales de clima han impuesto para el desarrollo de la agricultura: desvió ríos, construyó canales y reservorios y entregó el agua a los cultivos empleando variados sistemas de riego. En este caso haremos referencia al riego por chorro intermitente.

  2. Herstellung und Charakterisierung hoch poröser nanostrukturierter Filtermembranen

    OpenAIRE

    Mertler, Michael

    2007-01-01

    In dieser Arbeit wurden hoch poröse, nanostrukturierte Filtermembranen untersucht und ihre Eigenschaften charakterisiert. Diese Nanomembranen bieten einen erfolgversprechenden Ansatz zur Minimierung der Haftkräfte von stark adhäsiven Stäuben auf der Membranoberfläche. Dies wird einerseits durch die Verringerung der Korngrößen der Nanomembranen und andererseits durch die Bereitstellung von nur wenigen Kontaktstellen auf der Nanomembran angestrebt. Die Nanomembranen wurden als Beschichtung d...

  3. Glucogeno sintasa en helmintos parasitos: inhibicion por benzimidazoles

    OpenAIRE

    H. Gomez-Banqueri; M. A. Garcia Ruiz; M. Monteoliva; Sanchez-Moreno, M.

    1987-01-01

    Se ha determinado el effecto inhibidor sobre la actividad Glucogeno sintetasa (E.C.2.41.11) por parte de cuatro antihelminticos: Albendazol, Mebendazol, Parbendazol y Tiabendazol. Observandose que en todos los casos, es el Parbendazol quien ha demostrado un mayor poder inhibidor sobre la glucógeno sintetasa de Ascaris suum, Fasciola hepatica y Moniezia expansa. El Tiabendazol es el anti-helmintico que menor efecto inhibidor ha presentado sobre la enzima en los tres parasitos objeto de nuestro...

  4. Estrategias de mercadeo verde utilizadas por empresas a nivel mundial

    Directory of Open Access Journals (Sweden)

    Castellano, Susie

    2015-09-01

    Full Text Available La preocupación por el medio ambiente se ha convertido en una temática que inquieta a toda la colectividad actual, desde los más pequeños hasta los más grandes, desde la pequeña empresa hasta la gran industria. Sumado a esto, el auge de normativas ambientales que establecen regulaciones al empresario, los obliga a tener una mayor conciencia de los daños que pueden causar sus acciones al medio ambiente. Es por esto, que paulatinamente ha comenzado, por parte de las empresas, la adopción de estrategias en el área de mercadeo verde que les permita comercializar sus productos y servicios de forma que los mismos sean ambientalmente compatibles. En el presente trabajo, se abordaron las diferentes estrategias que han venido asumiendo empresas de diferente índole para hacer frente a tan importante filosofía en el ámbito mundial. Para tal fin, se hizo la revisión y contrastación de artículos escritos en el marco del mercadeo verde por Rivera y Molero (2006, Chamorro (2001, Samper y Echeverri (2008 principalmente, encontrándose que cada vez son más las empresas que se suman a esta forma de mercadear sus procesos y productos y más los consumidores que anteponen criterios ecológicos ante variables de otra índole, modificando sus hábitos de consumo.

  5. RESPONSABILIDAD INTERNACIONAL DEL ESTADO COLOMBIANO POR ACCIONES DE GRUPOS PARAMILITARES

    Directory of Open Access Journals (Sweden)

    Nataly Vargas Ossa

    2008-12-01

    Full Text Available El Sistema Interamericano constituye un espacio que permite observar la situación de los Derechos Humanos en América Latina, los mecanismos de protección a que acuden las víctimas y la actitud de los Estados frente a la promoción, protección y defensa de los Derechos Humanos. Bajo esta premisa es que el proyecto “Alcance y Descripción de los Derechos Humanos en el Sistema Interamericano de Protección de los Derechos Humanos”, utilizando el método dogmático documental, pretendió recopilar aquellas providencias que permiten recoger el concepto y el alcance que La Corte Interamericana ha desarrollado entorno a algunos Derechos Humanos, es así como el presente escrito hace parte de los resultados de dicho proyecto, el cual recopila las sentencias proferidas por la Corte Interamericana en contra del Estado Colombiano, por acciones de grupos paramilitares.El estado Colombiano en reiteradas oportunidades ha sido declarado internacionalmente responsable por violaciones a Derechos Humanos, debido a la conformación y apoyo de grupos “paramilitares“. En el presente escrito se busca retomar aquellas providencias emanadas de la Corte Interamericana, en lo que tiene que ver con la descripción y alcance de derechos por los cuales el Estado Colombiano ha sido condenado. En es orden de ideas son cuatro providencias objeto análisis del presente escrito: El Caso de los 19 Comerciantes, el Caso de la Masacre de Mapiripán, el Caso de las Masacres de Pueblo Bello, y el Caso de las Masacres de Ituango.

  6. Hepatotoxicidad inducida por azatioprina en paciente con enfermedad de Crohn

    Directory of Open Access Journals (Sweden)

    D. Ruiz-Clavijo

    2013-08-01

    Full Text Available Los inmunosupresores se encuentran entre los grupos farmacológicos con mayor potencial teórico de inducir reacciones adversas, entre ellas las hepáticas. Presentamos el caso de un paciente de 35 años con enfermedad de Crohn en tratamiento con azatioprina por corticodependencia al que se le diagnosticó tras realización de una biopsia hepática de hiperplasia nodular regenerativa secundaria a este tratamiento.

  7. Enfoque por competencias, ¿una respuesta al fracaso escolar?

    Directory of Open Access Journals (Sweden)

    Philippe Perrenooud

    2009-01-01

    Full Text Available Son tiempos de reflexión sobre las competencias. Queda mucho por investigar acerca de sus posibilidades pero es cierto que, desde el punto de vista teórico, el enfoque por competencias se presenta como potente al complementar una pedagogía que, tradicionalmente, se ha centrado en las disciplinas y en los saberes. Pero también este enfoque aparece fuerte en el campo de la formación en la medida en que viene vinculado a las prácticas sociales y educativas, al trabajo pedagógico de los problemas educativos en las diferentes situaciones, a los proyectos que los educadores desean materializar en sus lugares de trabajo. Están por demostrar las expectativas puestas en el enfoque por competencias y este texto trata de pensar toda una serie de cuestiones relacionadas con su puesta en marcha en los contextos formativos.---------------------------------------------------------------------These are times for reflection on skills. There is much left to investigate on their possibilities but it is true that, from the theoretical point of view, the skill approach appears to be powerful by complementing a pedagogy which, tradicionally, has focused on the knowledge and disciplines. But this approach appears strongly in the training field as it is linked to the social and educational practices, to the pedagogic work on educative problems, to the different situations, to the project that teachers wish to materialize in the labor places. Still to be demonstrated are the expectations on the skills approach, and this text tries to think on a series of matters related with its set in motion in the learning contexts.

  8. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Science.gov (United States)

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevención de más de 795 000 muertes por cáncer de pulmón en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este país hubiera cesado después de la publicación d

  9. Perforación intestinal por un palillo de dientes

    Directory of Open Access Journals (Sweden)

    Marvin Yglesias-Rosales

    2006-10-01

    Full Text Available Existe una gran variedad de cuerpos extraños que son deglutidos por los seres humanos, entre los cuales son numerosos los que pueden producir una perforación del tracto gastrointestinal. Se enfocará esta discusión en los palillos de dientes, caso particular, por poseer 2 extremos puntiagudos, lo que hace se consideren como portadores de una gran morbimortalidad. El espectro de manifestaciones clínicas asociado con las lesiones por palillos de dientes ingeridos es muy amplio; el diagnóstico de perforación del tracto gastrointestinal por cuerpo extraño es difícil de realizar en el pre-operatorio, ya que la mayoría de los pacientes no recuerdan haber ingerido algún cuerpo extraño. El pronóstico del paciente depende del diagnóstico oportuno, así como del tipo de abordaje, de las comorbilidades del paciente y de las complicaciones que refiera. Se presenta aquí el caso de un hombre con perforación ileal secundaria a la ingesta de 1palillo de dientes y que fue manejado con éxito. El diagnóstico diferencial del abdomen agudo, o lo que es más, del dolor abdominal agudo, es difícil, ya que en un espacio reducido se encuentran numerosas vísceras, con un variado repertorio de enfermedades cada una y con un limitado espectro de síntomas. En cuanto a los cuerpos extraños, la situación se complica todavía más, pues pueden afectar diferentes órganos y presentar una clínica intrascendente, posibilidad diagnóstica que hay que tener en mente al valorar un dolor abdominal.

  10. Riesgos por Legionella, Prevención y Control

    OpenAIRE

    Martín Romero, Magdalena

    2014-01-01

    Para un buen control de riesgos por Legionella pneumophila, es importante conocer con detalle esta bacteria, los efectos que causa en el hombre, las principales fuentes de contagio y los medios para evitarlo. Este es el objetivo del presente trabajo. La legionelosis a pesar de ser percibida como una enfermedad infecciosa potencialmente erradicable, se puede controlar con medidas higiénico- sanitarias en las instalaciones implicadas.

  11. por Penicillium digitatum: ¿se equivocaba Janzen?

    Directory of Open Access Journals (Sweden)

    J.E. Peris

    2015-01-01

    Full Text Available Janzen (1977 propuso que los vertebrados frugívoros prefieren los frutos sanos frente a los infectados por hongos y bacterias dado que los microbiosproducen compuestos tóxicos y antibióticos y, además, reducen el valor nutritivo de los frutos infectados. Valoramos dicha hipótesis mediante experimentosde campo en los que ofrecimos tres variedades comerciales de frutos del género Citrus sanos e infectados por Penicillium digitatum.Sorprendentemente, los frugívoros (principalmente conejos Oryctolagus cuniculus y roedores como la rata negra Rattus rattus y ratones, probablemente,Mus spretus y Apodemus sylvaticus prefirieron siempre los cítricos infectados a los frutos "control" sanos. En concreto, el consumo de frutosinfectados de las tres variedades estudiadas fue hasta 32 veces mayor en comparación con el consumo de frutos sanos. Proponemos tres hipótesisno excluyentes que podrían explicar la preferencia de los frutos infectados por mamíferos y otros vertebrados frugívoros.

  12. Uso de contraceptivos por puérperas adolescentes

    Directory of Open Access Journals (Sweden)

    Fernanda Schulz da Rosa

    2014-07-01

    Full Text Available Objetivo: Indagar el uso de métodos contraceptivos por las puérperas adolescentes a fin de relacionar su (desuso con el embarazo en la adolescencia. Método: Estudio transversal, descriptivo, realizado por medio de un instrumento estructurado con 181 puérperas adolescentes que tuvieron sus partos en el hospital participante de la investigación. Los datos fueron recolectados en el período de diciembre de 2008 a diciembre de 2009. Resultados: El 64,1% de las puérperas usaba algún método contraceptivo antes del embarazo; los métodos más utilizados fueron el anticoncepcional oral (51% y el preservativo masculino (29%. Para el 75% de las adolescentes el embarazo fue planeado y justificado por el deseo y la voluntad propia de experimentar la maternidad. Conclusión: Considerando que casi la mitad de las adolescentes entrevistadas deseaba el embarazo, se deduce que investigar y discutir apenas el uso o no de los métodos contraceptivos no es adecuado. Es necesario profundizar las investigaciones acerca de los significados de ser madre en la adolescencia.

  13. Diagnostico por PCR del complejo Sigatoka en Colombia.

    Directory of Open Access Journals (Sweden)

    Romero Magally

    1999-06-01

    Full Text Available Las Sigatokas negra y amarilla son enfermedades causadas por Mycosphaerella fijiensis y Mycosphaerella musicola respectivamente. Estas dos especies de hongos estrechamente relacionadas y morfológicamente similares, causan necrosis severa en las hojas de banano y plátano disminuyendo el área de tejido fotosintético y acelerando la maduración del fruto. Las enfermedades producidas por estos hongos afectan la mayoría de las áreas cultivadas de banano y plátano a nivel mundial, generando un gran problema económico y ambiental. Los síntomas que produce cada uno de estos patógenos en el cultivo son similares, por lo que su correcta identificación en campo se hace difícil. Con el fin de hacer una identificación precisa de cada uno de ellos decidimos estandarizar una prueba diagnóstica basada en la reacción en cadena de la polimerasa (PCR utilizando dos oligonucleótidos de 21 bases (MF 137 y MM 137 específicos para cada una de las especies M. fijiensis y M. musicola respectivamente. MF 137 y MM 137 codifican regiones variables identificadas en las secuencias interespaciadoras (ITS del DNA ribosomal.

  14. Extracción de sustancias asistida por ultrasonido (EUA

    Directory of Open Access Journals (Sweden)

    Rocío Azuola

    2007-11-01

    Full Text Available Compuestos presentes en los vegetales con propiedades funcionales o tecnológicas, han cobrado gran importancia en los mercados de alimentos, farmacéuticos y cosméticos. Se buscan métodos eficientes, económicos y favorables al ambiente para la extracción de estas sustancias. Se ha realizado un estudio bibliográfico de las publicaciones recientes sobre diferentes métodos de extracción y su comparación a las extracciones asistidas por ultrasonido (EAU con el fin de evaluar su eficacia y viabilidad industrial. Se ha encontrado que la EAU es más eficiente que los métodos de extracción tradicionales, y más económica y sencilla que los métodos de extracción no tradicionales como la extracción asistida por microondas, por lo cual se comprueba su viabilidad industrial.

  15. Confirmación por laboratorio de leptospirosis: laboratory confirmation

    Directory of Open Access Journals (Sweden)

    María De los Ángeles Valverde-Jiménez

    2008-03-01

    Full Text Available Se presenta el caso de un joven de quince años de edad que consulta a un hospital privado por enfermedad febril aguda de origen desconocido, asociada a elevación discreta de transaminasas y otras alteraciones inespecíficas de los exámenes de laboratorio. Fue referido para observación a un hospital de la Caja Costarricense de Seguro Social, donde se le maneja como cuadro de dengue clásico. La atención en la clínica privada se restableció luego de su egreso, se confirmó el diagnóstico de leptospirosis por parte del laboratorio del Centro Nacional de Referencia de Leptospirosis del iNCIENSA y se manejó con antibióticos hasta su resolución. El artículo enfatiza la importancia del diagnóstico de la leptospirosis mediante un alto grado de sospecha, una historia clínica precisa, un buen examen fisico y la confirmación diagnóstica por laboratorio con el fin de tratarla apropiadamente.

  16. Por una antropología de las emociones

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    David Le Breton

    2012-12-01

    Full Text Available En este texto, se analiza el carácter social de las emociones y la importancia de los contextos cul‐ turales en las encarnaciones y formas de experimentar el sentir afectivamente. Primero se discute la perspectiva naturalista del estudio de las emociones. Como se sostiene, los sentimientos y las emociones no son sustancias transferibles ni de un individuo ni de un grupo a otro, y no son sólo procesos fisiológicos. Son relaciones, y por tanto son el producto de una construcción social y cul‐ tural, y se expresan en un conjunto de signos que el hombre siempre tiene la posibilidad de des‐ plegar, incluso si no las sienten. La emoción es a la vez interpretación, expresión, significación, re‐ lación, regulación de un intercambio; se modifica de acuerdo con el público, el contexto, se diferencia en su intensidad, e incluso en sus manifestaciones, de acuerdo a la singularidad de cada persona. Como se argumenta, el individuo añade su nota en un patrón colectivo susceptible de ser reconocido por los pares (de acuerdo con su historia personal, psicología, estatus social, sexo, edad, etc. La afectividad es el impacto de un valor personal que se enfrenta a un contexto tal y como es experimentado por el individuo.. 

  17. El principio general de reductio ad aequitatem por desequilibrio contractual

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    José Félix Chamie

    2012-06-01

    Full Text Available Para atender las exigencias del mundo actual se requiere de la proposición de categorías dogmáticas que contribuyan en el desarrollo del sistema jurídico unificando conceptos, simplificando caminos interpretativos, y sobre la base de la propia tradición rediseñar instrumentos para mejorar el derecho poniéndolo a tono con las exigencias de su tiempo. De allí la intención del autor de aventurarse en una reconstrucción histórico-dogmática de figuras bien conocidas por la tradición del sistema jurídico romano-germánico, en aras de identificar un principio de moderación en los contratos. Un principio de equilibrio que desde los tiempos de la Escuela medieval se contiene en la expresión reductio ad aequitatem y se realiza mediante instrumentos que procuran corregir y adaptar el contrato según el caso. Así, el autor se fija en los momentos de la celebración y de la ejecución del contrato para observar la ratio de los institutos que en esos momentos del iter contractual sirven la causa de la equidad para ajustar la sinalagmaticidad de la relación, contrastar abusos y desequilibrios causados por las partes o por eventos extraños al riesgo del contrato.

  18. DE ACUMULACIÓN POR DESPOSESIÓN

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    Sebastián Gómez Lende

    2015-01-01

    Full Text Available Omnipresente, la acumulación por desposesión es uno de los elementos centrales del orden global contemporáneo. Observados desde una perspectiva crítica, los usos extractivos del territorio constituyen una de las principales expresiones de ese proceso. A la luz de ese sistema de ideas, este artículo procura demostrar que el modelo sojero actualmente vigente en la Argentina es una de las formas más completas, exhaustivas, actuales y sofisticadas, de acumulación por desposesión en el país. En ese sentido, el artículo analiza el boom de la soja transgénica y sus vínculos con las formas tanto seculares (endeudamiento financiero, concentración de la propiedad rural, usurpación de la tierra y actuales de desposesión (degradación de la naturaleza, despojo del derecho a la salud, pillaje de recursos genéticos efectuadas por los grandes agricultores, el capital financiero, las agroindustrias y las corporaciones biotecnológicas, en detrimento de los pequeños productores, los campesinos, los pueblos aborígenes y la población en general.

  19. GRAVIDADE DE INTOXICAÇÕES POR SANEANTES CLANDESTINOS

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    Jessica Adrielle Teixeira Santos

    2011-01-01

    Full Text Available El presente estudio tuvo como objetivo analizar las intoxicaciones por saneantes comercializados clandestinamente, reportadas en el Centro de Control de Intoxicaciones del Hospital Universitario Regional de Maringá. Es un estudio cuantitativo, con análisis retrospectivo de registros epidemiológicos de personas intoxicadas por estos agentes, en el período de enero de 2005 a diciembre de 2009. De los 118 casos reportados, la mayoría (74-62,7% se produjeron en varones, 105 (88,9% necesitaron de asistencia en unidades de atención de emergencia y hospitalización de alta complejidad, en 14 casos (11,8% requirieron de Cuidados Intensivos, y se reportaron cinco óbitos, todos por intoxicación intencional. Los resultados demuestran la gravedad y la letalidad de este tipo de intoxicación, sugieren la necesidad de medidas urgentes de fiscalización y control de la Vigilancia Sanitaria, así como de medidas para la educación de los consumidores, haciendo hincapié en el papel educativo de la Enfermería

  20. Pseudoobstrucción intestinal por Ascaris lumbricoides

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    Alessio Garro Donini

    2015-12-01

    Full Text Available La ascariosis es una geohelmintosis, ya que el agente causal requiere de la tierra para que se forme la fase infectiva para el hombre, que en este caso la fase es el huevo larvado conteniendo la larva de segundo estadio. Es una infección producida por el nematodo Ascaris lumbricoides, uno de los parásitos descritos desde la antigüedad (Becerril, 2008. Esta parasitosis tiene gran importancia epidemiológica, pues las zonas donde se presenta con mayor frecuencia son las de gran pobreza; aquellas donde la gente acostumbra a defecar a ras del suelo, pues no tiene el recurso económico necesario para construir baños, ni dispone de agua potable. Esta parasitosis afecta a 25 a 35% de la población mundial (Biagi, 2004 (Becerril, 2008. Generalmente los pacientes infectados por este nematodo cursan asintómaticos, pero en caso contrario la sintomatología dependerá de la fase del ciclo vital en la que el parásito se encuentre pudiendo existir síntomas pulmonares o gastrointestinales, incluso en ciertas poblaciones como la pediátrica podría incluso ocasionar la muerte por múltiples mecanismos dentro de los cuales se incluyen la migración errática y/o la obstrucción intestinal (MS., 1996

  1. Reliable Data Delivery in MANETs Using POR Protocol

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    B. Sunil Kumar

    2013-03-01

    Full Text Available This balance addresses the company of release matter packets for stage sprightly mercurial beating the drum hoc networks in a reliable and timely manner. Most suitable verifiable propaganda hoc routing protocols are susceptible to node mobility, especially for large-scale networks. Dominated by this topic, we clench an apt Position-based Exploitive Routing (POR rite which takes give a reason for of the stateless acquiring of geographic routing and the broadcast nature of wireless medium. At the drop of a hat a information collection is sent about, several of the neighbor nodes stray shot overheard the publish resoluteness satisfy as alteration lawn, and round play the part to prepay the package dispatch if it is whine relayed by the specific best forwarder within a certain period of time. By utilizing such in-the-air every other, message is maintained without being interrupted. The bells latency incurred by inbred tour improvement is broadly tuppence inexpensively and the replica relaying caused by packet reroute is also decreased. In the scrap of notice opening, a Look up Destination-based Delete Comport (VDVH desire is in the deep-freeze proposed to work together with POR. Both outline enquiry and affectedness benefits show mosey POR achieves superior achievement unruffled here brazen node mobility with acceptable overhead and the new void handling scheme also works well

  2. Por que rir da Filosofia Política?: Abertura

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    Lessa Renato

    1998-01-01

    Full Text Available As diferentes intervenções que compuseram este debate têm como referência comum uma reflexão sobre os lugares da Filosofia Política na tradição disciplinar que designamos como Ciência Política. Recusando a perspectiva que dissocia a Filosofia Política da dimensão empiricamente orientada da disciplina, os argumentos apresentados destacam o papel de fertilização de formas de vida cumprido pela primeira. A agenda dos pesquisadores devotados à boa faina da investigação empírica foi, e segue sendo, em grande medida definida e configurada por exercícios prévios de invenção social e política e por decisões de ordem ontológica, epistemológica e retórica. Neste sentido, a distinção entre ciência e filosofia é, além de obscurantista e marcada por enorme otimismo epistemológico, sintoma de um desconhecimento forte com relação à história do conhecimento político.

  3. Consumo de carnes por adolescentes do Sul do Brasil

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    Maria Cecília Formoso Assunção

    2012-08-01

    Full Text Available OBJETIVO: Descrever a frequência de consumo de diferentes tipos de carnes conforme variáveis sociodemográficas e nutricionais, e analisar o consumo, em adolescentes do Sul do Brasil, de dieta rica em gordura conforme os tipos de carne consumidos. MÉTODOS: Estudo transversal realizado com adolescentes pertencentes à coorte de nascimentos de 1993, em Pelotas (RS. A frequência de consumo de carnes vermelhas, brancas, vísceras e embutidos foi avaliada por um Questionário de Frequência de Consumo Alimentar, adaptado para este estudo. A ingestão de dieta rica em gordura foi avaliada a partir do instrumento proposto por Block. As variáveis independentes foram sexo, cor da pele, nível socioeconômico, escolaridade materna e estado nutricional. Nas análises estatísticas, foram utilizados testes Qui-quadrado de heterogeneidade e de tendência linear. RESULTADOS: Foram avaliados 4.325 adolescentes com idade média de 14,7, DP=0,3 anos, dos quais 51,2% eram do sexo feminino. A frequência de consumo diário de carnes vermelhas foi maior do que a de carnes brancas (43,0% e 9,7%, respectivamente. O consumo de embutidos por mais do que quatro vezes por semana foi referido por 48,5% dos indivíduos, e 81,4% relataram consumir vísceras raramente ou nunca. Adolescentes de maior nível socioeconômico e filhos de mães com maior escolaridade apresentaram maior consumo de carnes vermelhas e embutidos, enquanto aqueles em situação oposta apresentaram maior consumo de carnes brancas. Adolescentes que consomem carnes com maior frequência também consomem dieta rica em gordura. CONCLUSÃO: As carnes consumidas com maior frequência pelos adolescentes foram as vermelhas e os embutidos. No entanto, adolescentes de maior nível socioeconômico consomem carnes vermelhas com maior frequência, enquanto adolescentes menos favorecidos economicamente consomem mais carnes brancas.

  4. Maculopatia tóxica por cloroquina Chloroquine toxic maculopathy

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    Nikias Alves da Silva

    2009-06-01

    Full Text Available O fosfato de cloroquina é uma droga largamente utilizada no tratamento de doenças crônicas de autoagressão, mais comumente no controle da artrite reumatóide, do lupus eritematoso discóide ou disseminado, da porfiria cutânea, da urticária solar e outras afecções dermatológicas. Embora a incidência de toxicidade retiniana por esta droga seja baixa, mesmo com o emprego da dose máxima recomendada, sua ocorrência tem grande relevância por acometer a região macular com importante e irreversível comprometimento visual. Trata-se no presente caso de uma paciente de 44 anos, portadora de artrite reumatóide há 19 anos, que fez uso de fosfato de cloroquina na dose de 250 mg/dia durante dois períodos de 4 e 3 anos, intercalados por um período de 8 anos em que usou methotrexate. Ao final do segundo período de uso da cloroquina, foi observada a maculopatia, a partir de quando a droga foi definitivamente substituída por methotrexate e prednisona. Por seu caráter típico e conspícuo, a maculopatia em questão se presta muito bem para ilustrar os achados dos principais métodos propedêuticos que devem ser empregados para caracterizá-la, inclusive a tomografia de coerência óptica.Chloroquine phosphate is widely used for the treatment of chronic autoimune diseases, most commonly rheumatoid arthritis, discoid or disseminated lupus erythematous, light sensitivity eruptions as well as other dermatologic affections. Although the incidence of retinal toxicity by this drug is low even with the maximally recomended dose, its occurrence is relevant because it damages the macula with an important and irreversible visual impairment. A 44-year-old white female patient who had suffered from rheumatoid arthritis for about 19 years had been under treatment with chloroquine phosphate in the daily dose of 250 mg during two periods of 4 and 3 years, intercalated by an 8-year period of methotrexate usage. At the end of the 3-year period, a maculopathy

  5. Intoxicação por monofluoroacetato em animais

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    Vivian Assunção Nogueira

    2011-10-01

    Full Text Available O monofluoroacetato (MF ou ácido monofluoroacético é utilizado na Austrália e Nova Zelândia no controle populacional de mamíferos nativos ou exóticos. O uso desse composto é proibido no Brasil, devido ao risco de intoxicação de seres humanos e de animais, uma vez que a substância permanece estável por décadas. No Brasil casos recentes de intoxicação criminosa ou acidental têm sido registrados. MF foi identificado em diversas plantas tóxicas, cuja ingestão determina "morte súbita"; de bovinos na África do Sul, Austrália e no Brasil. O modo de ação dessa substância baseia-se na formação do fluorocitrato, seu metabólito ativo, que bloqueia competitivamente a aconitase e o ciclo de Krebs, o que reduz produção de ATP. As espécies animais têm sido classificadas nas quatro Categorias em função do efeito provocado por MF: (I no coração, (II no sistema nervoso central (III sobre o coração e sistema nervoso central ou (IV com sintomatologia atípica. Neste trabalho, apresenta-se uma revisão crítica atualizada sobre essa substância. O diagnóstico da intoxicação por MF é realizado pelo histórico de ingestão do tóxico, pelos achados clínicos e confirmado por exame toxicológico. Uma forma peculiar de degeneração hidrópico-vacuolar das células epiteliais dos túbulos uriníferos contorcidos distais tem sido considerada como característica dessa intoxicação em algumas espécies. O tratamento da intoxicação por MF é um desafio, pois ainda não se conhece um agente capaz de reverte-la de maneira eficaz; o desfecho geralmente é fatal

  6. Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China

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    Tang Renxian

    2010-11-01

    Full Text Available Abstract Background Variations of porB1A and porB1B genes and their serotypes exist in Neisseria gonorrhoeae isolates from different geographical areas, and some site mutations in the porB1B gene correlate with drug resistance. Methods The β-lactamase production of N. gonorrhoeae isolates was determined by paper acidometric test and nitrocefin discs. The porB1A and porB1B genes of 315 non-penicillinase-producting N. gonorrhoeae (non-PPNG strains were amplified by PCR for sequencing to determine serotypes and site mutations. A duplex PCR was designed to simultaneously detect both porB1A and porB1B genes. Penicillin and tetracycline resistance was assessed by an in vitro drug sensitivity test. Results Of the N. gonorrhoeae isolates, 31.1% tested positive for porB1A and 68.9% for porB1B genes. All the 98 porB1A+ isolates belonging to IA6 serotype with either no mutation at the 120 and 121 sites (88.8% or a D120G (11.2% mutation and were no resistance to both penicillin and tetracycline. Among the 217 porB1B+ isolates, 26.7%, 22.6% and 11.5% belonged to IB3, IB3/6 and IB4 serotypes, respectively. Particularly, two novel chimeric serotypes, IB3/6-IB2 and IB2-IB4-IB2, were found in 77 and 8 porB1B+ isolates. Two hundred and twelve (97.7% of the porB1B+ isolates were presented G120 and/or A121 mutations with 163 (76.9% at both sites. Interestingly, within the 77 porB1B+ isolates belonging to IB3/6-IB2 serotype, 15 were discovered to possess novel deletions at both A121 and N122 sites. All the replacement mutations at these sites in PorB1B were correlated with resistance and the deletion mutation showed the highest resistance. Conclusion N. gonorrhoeae isolates circulating in Eastern China include a sole PorB1A serotype (IA6 and five PorB1B serotypes. Multiple mutations in porB1B genes, including novel A121 and N122 deletions, are correlated with high levels of penicillin and tetracycline resistance.

  7. Intoxicación por metales Metal poisoning

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    A. Ferrer

    2003-01-01

    Full Text Available Los metales están entre los tóxicos más antiguos conocidos por el hombre. En el industrializado mundo actual las fuentes de exposición a metales son ubicuas tanto en el campo laboral como a partir de agua, los alimentos o el ambiente contaminados. Su toxicidad está caracterizada por el elemento metálico en cuestión pero se ve modificada por el tipo de compuesto, orgánico o inorgánico y sus características de hidro o liposolubilidad, que determina su toxicocinética y por tanto sus posibilidad de alcanzar sus dianas. Las biomoléculas más afectadas por los metales son las proteínas con actividad enzimática por lo que su patología es multisistema. Los principales sistemas afectados son el gastrointestinal, neurológico central y periférico, hemático y renal. Algunos de los compuestos metálicos son carcinógenos. Los metales se benefician de un tratamiento condicionado por su reactividad química. Pueden ser inactivados y eliminados mediante la administración de substancias quelantes que producen con ellos moléculas complejas, atóxicas y excretables. Los principales agentes quelantes son: BAL (British Anti-Lewisite o dimercaprol, DMPS (ácido 2,3-dimercapto-1-propanosulfonico y DMSA (ácido meso-2,3-dimercatosuccínico o Succimer, EDTA, Penicilamina (ß,ß-dimetilcisteína y Desferoxamina. Se exponen a continuación las características toxicocinéticas, mecanismo de acción, clínica y tratamiento de alguno de los metales y metaloides más relevantes: plomo, mercurio y arsénico.Metals are amongst the oldest toxic substances known to man. In today’s industrialized world the sources of exposure to metals are ubiquitous both in the field of work and from polluted water, foodstuffs and the environment. Their toxicity is characterized by the metallic element in question, but this is modified by the type of compound, whether organic or inorganic, and its characteristics of hydrosolubility and liposolubility, which determines its

  8. La desnaturalización de una proteina globular por surfactantes es monotorizada por espectroscopia Raman quiral

    OpenAIRE

    Nieto-Ortega, Belen; Hierrozuelo, José M.; Carnero Ruiz, Cristóbal; López Navarrete, Juan T.; Casado Cordón, Juan; Ramirez, Francisco J.

    2013-01-01

    Desnaturalización de proteínas por surfactantes ha recibido una gran atencion los últimos años debido a sus implicaciones en productos farmacéuticos, cosméticos. A lo largo de esta comunicacion se demuestra la capacidad de la espectroscopia ROA para seguir este proceso Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.

  9. El daño tisular por sobrecarga de cobre esta mediado por estres oxidativo-nitrativo

    OpenAIRE

    Arnal, Nathalie; Hurtado de Catalfo, Graciela E.; García, M; Galletti, S.; Errecalde, Ana Lía; Tacconi de Alaniz, María J.; Marra, Carlos Alberto

    2010-01-01

    Objetivo del trabajo: estudiar los efectos de una sobrecarga de cobre moderada y sub-crónica en un modelo de ratas Wistar con el fin de establecer si provoca daños tisulares evidenciables por medio de estudio histopatológico, y si esos daños se hallan asociados a la producción de especies reactivas del oxígeno o del nitrógeno

  10. Ni por la razón, ni por la fuerza. El fallido intento del Estado nacional por incorporar a los pueblos mapuche y pehuenche. (1810-1835

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    Paulina Peralta Cabello

    2011-05-01

    Full Text Available Resumen. En este artículo se analizan las relaciones establecidas, a principios del siglo XIX, entre el Estado chileno republicano recién fundado y las comunidades autóctonas que vivían al sur del río Biobío. Más específicamente, se distingue desde los albores del proceso independentista, sobre todo a partir de la década de 1820, un afán por incorporar al proyecto nacional los territorios ubicados al sur de esta frontera, así como también a sus habitantes. Dentro de las estrategias jurídicas y políticas esgrimidas por el poder dirigente para hacer efectiva esta intención, es posible identificar el ofrecimiento temprano de nacionalidad chilena, así como también de una condición particular de ciudadanía, entendida sólo en una lógica de deberes y no derechos políticos. Sin embargo, esta estrategia no pudo ser puesta en práctica, pues la mayor parte de las comunidades autóctonas a las que iba destinada opuso una tenaz resistencia al régimen instaurado, dado que no percibieron las supuestas ventajas del régimen republicano. Asimismo, se sostiene que esta resistencia, mantenida por los naturales durante décadas en el territorio sur de la naciente república, no sólo hizo fracasar dicha estrategia, sino que también fue minando el discurso más ilustrado e incluyente propio de los primeros decenios, el cual fue siendo reemplazado desde mediados de 1830 por uno relativamente excluyente, o mejor dicho, incluyente territorialmente –dado el creciente interés económico que comenzaron a despertar estas tierras en los chilenos–, pero excluyente en relación a sus habitantes. Palabras Claves: Ciudadanía Política, Relaciones Étnicas, Estado Chileno (Siglo XIX. Abstract. This article analyzes the relations between Chile’s recently established republican State and the indigenous communities then living south of the Bío Bío River. More specifically, it identifies, since the beginnings of the independence process, but

  11. Tallado de hélices por el método de copiado por proyección

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    José Vicente Fierro Vasco

    2012-04-01

    Full Text Available Este dispositivo fue diseñado como parte de la investigación sobre Aerogeneradores que se está llevando a cabo en el Departamento de Ingeniería Mecánica, cuyo investigador principal es el Ing. Julio Mario Rodríguez Devis. Como parte inicial de la investigación se adecuó un túnel situado en el Laboratorio de Hidráulica para hacer las pruebas de modelos. En la construcción de dichos modelos se requiere una buena precisión en la hechura de las aspas del molino, en especial por el tamaño reducido de liste. Se debe garantizar que el perfil aerodinámico se conserve a lo largo del aspa, por lo que se requiere de un dispositivo capaz de tallar los álabes con la precisión y rapidez necesarias. Los resultados del trabajo fueron presentados al concurso del premio Worthington de la Ingeniería Colombiana 1982 (Categoría estudiantes, por los estudiantes que trabajaron en el proyecto, siendo acreedores al primer puesto.

  12. Descenso de los niveles de propéptido natriurético de tipo B-N terminal luego de la reversión de pacientes con fibrilación auricular y función ventricular conservada NT-Pro-BNP levels performance before and after reversion to sinus rhythm in patients with preserved ventricular function

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    Claudio Higa

    2011-04-01

    Full Text Available El objetivo fue comparar los niveles de Pro Péptido Natriurético tipo B-N terminal (Pro-BNP-NT basales y post reversión en pacientes con fibrilación auricular solitaria (FAS de comienzo reciente y con función ventricular izquierda conservada. Se determinaron niveles del Pro BNP NT antes y después de su reversión en treinta pacientes con FAS de comienzo reciente y fracción de eyección de ventrículo izquierdo ≥ 50%. Basalmente, los niveles de Pro BNP NT fueron significativamente más elevados respecto a un grupo control sano: 529 pg/ml (157-1763 versus 31.5 pg/ml (24-76, p Our objective was to evaluate changes of N-terminal pro-BNP (NT-Pro-BNP levels at baseline and after restoration to sinus rhythm in hemodynamic stable patients with lone atrial fibrillation (LAF with preserved left ventricular function. NT-Pro-BNP levels were obtained before and after cardioversion in thirty hemodynamic stable patients with LAF and preserved left ventricular function. At baseline levels of NT-Pro BNP levels were significatively higher than a normal control group. NTPro-BNP levels decreased significantly following cardioversion from 529 (157-1763 to 318 (98-870 pg/ml, p < 0.0001. Decreasing of N-terminal pro-BNP concentrations was observed after any mode of cardioversion: electrical or pharmacologic, 345 (153-1151 pg/ml to 169 (86-407 pg/ml, p: 0.02 and from 1624 (541-4010 pg/ml to 856 (532-1160 pg/ml, p < 0.001, respectively. N-terminal pro-BNP decreasing was observed mainly in patients with length of LAF longer than 8 hours: 1289 (338-2103 to 410 (169-905 pg/ml, p < 0.001 but no difference was detected when such length was less than 8 hours: 274 (137-2300 to 286 (82-1440, p = NS. Our study showed that baseline levels of NT-pro-BNP decreased shortly after reversion of patients with LAF to sinus rhythm. This performance occurs predominantly in patients with LAF length of at least eight hours.

  13. 经皮刺激迷走神经左侧耳支拮抗快速心房起搏对肺静脉及心房有效不应期的影响%Transcutaneous electrical stimulation in left auricular branch of the vagus nerve inhibts atrial fibrillation induced by six hours atrial pacing

    Institute of Scientific and Technical Information of China (English)

    蒋思源; 李睿; 夏豪; 李朋; 程俊; 饶国涛

    2013-01-01

    Objective To investigate the inhibitory effects of transcutaneous electrical stimulation in left auricular branch of the vagus nerve on atrial fibrillation induced by six hours atrial pacing.Methods Fourteen adult dogs were underwent intercostal thoracotomy after anesthesia from both sides,and then were randomly divided into two groups.The control group (n=7) was only received 6 hours rapid atrial pacing(RAP) ; The TVNS group (n=7) was applied 6 hours RAP and concomitant 20% threshold TVNS.The threshold was the lowest voltage that slowed down sinus rhythm via TVNS.Effective refractory period (ERP)was measured at mutiple atrial and pulmonary vein sites by each hour.Results In the control group,ERP progressively shortened,while the ERP dispersion progressively increaseds; In the TVNS group,6 h concomitant RAP+TVNS did not induce any significant change in ERP and ERP dispersion.Condusions TVNS can suppress atrial fibrillation induced by 6 h RAP.%目的 探讨经皮刺激迷走神经左侧耳支(TVNS)拮抗快速心房起搏对肺静脉及心房有效不应期的影响.方法 14只成年犬,麻醉后双侧第4肋间开胸,心房快速起搏6h诱导心房急性电重构.犬随机分为:对照组(n=7)和TVNS组(n=7).TVNS组在心房快速起搏时同时给予20%阈强度的TVNS,TVNS引起窦性心率减慢的最低电压为阈强度电压.在基础状态和每小时末测定心房和肺静脉各部位的有效不应期(ERP).结果 对照组中,心房快速起搏6h导致各部位ERP逐渐降低,ERP离散度变大.TVNS组中,给予TVNS后抑制了心房快速起搏6h所导致的ERP、ERP离散度的变化.结论 TVNS可拮抗快速心房起搏对肺静脉及心房有效不应期的影响.

  14. Respuesta hipotensora al tratamiento agudo con péptido natriurético auricular: su relación con la expresión y la actividad de la óxido nítrico sintetasa cardíaca en ratas espontáneamente hipertensas

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    Cristina T. Arranz

    2007-01-01

    Full Text Available IntroducciónEl péptido natriurético auricular (ANP y el óxido nítrico (NO aumentan la diuresis y la natriuresis y disminuyen el tono vascular. Previamente demostramos que el NO está involucrado en el efecto hipotensor del ANP en ratas normotensas.ObjetivoEstudiar el efecto del ANP sobre la presión arterial media (PAM y el sistema del NO en ratas espontáneamente hipertensas (SHR y Wistar Kyoto (WKY y la participación de la isoforma inducible de la NO-sintasa (iNOS.Material y métodosProtocolo 1: los animales fueron infundidos con soluci��n salina (0,05 ml/min o con ANP (0,2 μg/kg/min durante 1 hora. Se determinaron: PAM y nitritos y nitratos urinarios (NOx. Se extrajo el corazón y se determinaron la actividad, con L-[U14C]-arginina, y la expresión (Western blot de iNOS y NOS endotelial (eNOS. Protocolo 2: luego del agregado de ANP (1 μM, cANP(4-23 (agonista NPR-C,1μM o aminoguanidina (inhibidor de iNOS, 1 μM se determinó la actividad de la NOS en la aurícula derecha y en el ventrículo izquierdo de SHR y WKY.ResultadosLa infusión con ANP disminuyó la PAM y aumentó los NOx en ambos grupos. La actividad NOS fue mayor en SHR y se incrementó con la infusión de ANP. Se observaron niveles proteicos mayores para eNOS e iNOS en SHR, que no se modificaron con ANP. La actividad basal de iNOS fue mayor en SHR. En la aurícula, el ANP sólo interactuaría con el NPR-C para activar la NOS y en el ventrículo también participarían los receptores NPR-A/B. El desarrollo y/o el mantenimiento de la hipertensión en este modelo experimental involucraría alteraciones en la interacción entre ambos sistemas, ANP y NO.

  15. Efecto de la quercetina sobre la nefrotoxicidad producida por cadmio

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    A. I. Morales Martín

    2004-01-01

    Full Text Available El incremento en la producción anual de cadmio ha favorecido que la incidencia de la intoxicación crónica por este elemento haya aumentado en los últimos años. El estrés oxidativo es uno de los mecanismos implicados en la generación del efecto tóxico, manifestándose, entre otras patologías, por una disfunción y lesión renal. La quercetina, un flavonoide muy abundante en la dieta mediterránea, es un potente antioxidante y un buen quelante de metales. Nuestro objetivo fue estudiar si la administración de quercetina pudiera prevenir la aparición de los procesos nefrotóxicos asociados a la exposición crónica al cadmio. Los experimentos se realizaron con ratas Wistar (200g, incluidas en tres grupos experimentales: 1 ratas a las que se administró cadmio (1,2 mg/kg/día, s.c. cinco veces por semana, durante nueve semanas, 2 ratas a las cuales se les administró quercetina (50 mg/kg/día, i.p. cinco veces por semana, empezando en la cuarta semana y 3 ratas a las que se administró cadmio y quercetina. La lesión renal se evaluó midiendo proteinuria, microalbuminuria y glucosuria, así como la excreción de enzimas urinarias N-acetil-beta-D-glucosaminidasa, fosfatasa alcalina y gamma-glutamil-transpeptidasa. Las muestras de plasma se utilizaron para la determinación de creatinina y nitrógeno ureico plasmático, así como dialdehido malónico, como índice de peroxidación lipídica y antioxidantes totales en plasma. En riñón se midió la actividad enzimática de la superóxido dismutasa y de la glutation reductasa. Nuestros resultados mostraron que la administración de cadmio durante 9 semanas produjo un incremento en los valores de flujo urinario, proteinuria, microalbuminuria y glucosuria. El tratamiento con cadmio incluso incrementó la creatinina sérica y el nitrógeno uréico plasmático y elevó drásticamente la actividad de enzimas urinarias. Finalmente el aclaramiento de creatinina disminuyó como consecuencia de la

  16. Movilización popular por la salud en Bolivia

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    Javier Torres Goitia T.

    2010-01-01

    Full Text Available Se presenta la experiencia de una política de salud democrática y participativa que pudo aplicarse exitosamente en Bolivia simultáneamente con la recuperación de la democracia después de 18 años de gobiernos de facto y dictaduras militares. Esta experiencia estuvo inspirada en los conceptos emergentes de la medicina social y tuvo como base una forma de concebir la participación popular en salud muy diferente a la tradicional que busca que la población coopere con los servicios. Lo que la experiencia boliviana señala es que son los profesionales del área de salud los que deben cooperar con la población en la conquista de sus reivindicaciones y derechos, uno de los cuales es el Derecho a la Salud. Se analiza el importante papel que cumplieron los Comités Populares de Salud por un lado y médicos especialmente capacitados por otro, para acometer una serie de movilizaciones que lograron impactos importantes como la desaparición del bocio endémico que afectaba al 65.5% de la población escolar, la reducción de la mortalidad infantil de 200 por mil a 75 en un período de 10 años, la desaparición de enfermedades inmunoprevenibles como la poliomielitis y el sarampión y otros avances importantes.

  17. Consumo de pre-adultos de mosquitos por peces ornamentales

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    Marco Polo Franco Archundia

    2015-01-01

    Full Text Available La investigación sobre alternativas de alimento para especies acuáticas con alto potencial económico, es uno de los principales temas de estudio en la acuicultura. En la presente investigación se evaluó el consumo de pre-adultos de mosquito por cuatro especies ícticas ornamentales: Carassius auratus, Pterophyllum scalare, Danio rerio y Xiphophorus helleri. El diseño experimental consistió en cuatro tratamientos, con tres réplicas. Cada ensayo se realizó de manera independiente entre especies. En cada acuario (1 l se colocaron dos peces juveniles, con peso húmedo y longitud total (promedio ± desviación estándar conocidos. Se suministraron en un tratamiento 100 larvas y en otro 100 pupas de mosquito. La tasa diaria de consumo de larvas y pupas se registró a un intervalo de tres horas durante un ciclo de 24 horas por especie. El peso húmedo de pre-adultos de mosquito difirió 5.20% y el seco 37.69%; en ambos casos, superior en las pupas (p < 0.001. Los peces fueron más activos durante la fase luminosa, 09:00-18:00 h, evidenciado por una mayor tasa de consumo de larvas y pupas de mosquito. Carassius auratus presentó el mayor consumo de larvas/pez/24 horas 131.33 ± 4.16 y de pupas/pez/24 horas 86.16 ± 3.20. Lo anterior difirió significativamente con respecto a P. scalare, D. rerio y X. helleri (p < 0.001. Finalmente, Carassius auratus presentó la mayor capacidad de consumo de pre-adultos de mosquitos.

  18. La Criatura de Frankenstein y la lucha por el reconocimiento

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    Hardisson Rumeu, Ana

    2002-06-01

    Full Text Available This text of Mary Shelley permits the possibility of considering the character of the «Creature» from the Axel Honneth`s perspective of the Ethics of reconnaissance. From this point of view, the dramatic sense of this novel moves round identity´s problem. The essential condition to build identity is the recognition from each to other. That is why identity can not be obtain in the sense of solitarious consciousness, but requires of intersubjetivity. The Creature becomes deprived of recognition, even by Frankenstein who has created him. This Creature becomes perverse because this privation, when the most elemental right of human being so as being someone and having an identity, is denied to him. His wickedness is the secondary effect of exclusion and suffering.

    Este texto de Mary Shelley, permite la posibilidad de considerar el personaje de la «Criatura» desde la perspectiva de la Ética del reconocimiento, de Axel Honneth. Desde este punto de vista, la carga dramática de esta novela gira en torno al problema de la identidad. La condición imprescindible para construir la identidad es el reconocimiento por parte del otro. Por eso la identidad no se puede adquirir en el plano subjetivo de la conciencia solitaria sino que precisa de la intersubjetividad . La criatura se ve privada de reconocimiento, incluso por parte de Frankenstein, que lo ha engendrado. Esa privación, al negarle el derecho más elemental del ser humano, que es ser alguien y tener una identidad, lo vuelve perverso. Su maldad es el efecto secundario de la marginación y el sufrimiento.

  19. Darwin por Manoel Bomfim Darwin by Manoel Bomfim

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    Celso Noboru Uemori

    2008-01-01

    Full Text Available A noção de "luta pela existência" de Charles Darwin foi apropriada por diversas tendências intelectuais e serviu a vários propósitos políticos. Ela deu suporte para aqueles que queriam legitimar o capitalismo, fazer apologia do individualismo, do mercado, do fim dos monopólios e da competição. Ensejou concepções conservadoras como a prática da eugenia, a justificação do elitismo, da conquista e da colonização dos europeus sobre as populações asiáticas e africanas e o racismo. A idéia de luta pela existência foi trabalhada, também, por intelectuais que defendiam a idéia de que lutar pela vida relacionava-se à solidariedade e à cooperação. Manoel Bomfim sofreu influência de Darwin e beneficiou-se de suas idéias para elaborar argumentos, graças aos quais foi visto por seus intérpretes como um autor "radical" e original.Charles Darwin's notion of a 'struggle for existence' has been appropriated by several intellectual currents of opinion, and used for various political purposes. It has served to support free market capitalism, as an apologia of individualism, the market, the end of monopolies, and competition. Conservative conceptions have been based on it: the practice of eugenics, the justification of elitism, of the conquest and colonization of Asian and African peoples by the European, and of racism. On the other hand, the idea of a struggle for existence has been worked on by intellectuals who argued that it was related to solidarity and cooperation. Manoel Bomfim was influenced by Darwin and used his ideas to form arguments which have led his interpreters to see him as a 'radical' and original author.

  20. Estudio del modelo de desgaste propuesto por Archard

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    FABIO ALEXANDER SUÁREZ BUSTAMANTE

    2005-01-01

    Full Text Available El comportamiento de componentes de máquinas y de materiales necesita ser optimizado para reducir los costos de operación en las plantas industriales. Este hecho ha impulsado la Tribología, un área relacionada con el estudio de la fricción, la lubricación y el desgaste. Uno de los principales objetivos de esta área del conocimiento es elaborar modelos matemáticos para expresar la variación del desgaste durante el contacto de superficies en movimiento, con el fin de predecir la vida útil de los elementos de máquinas. El modelo de Archard para desgaste por deslizamiento en seco, formulado en 1953, es un modelo clásico que plantea una variación del desgaste inversamente proporcional a la dureza del material y directamente proporcional a la carga aplicada. En el presente trabajo, se ha utilizado el método de modelamiento de problemas físicos, propuesto por Asbhy, para analizar los modelos propuestos por Archard (Modelo de contactos múltiples en superficies rugosas y modelo de desgaste mecánico. Con base en él se ha podido realizar un análisis profundo a dichos modelos, mostrando un panorama más amplio del modelo de Archard; se discuten aspectos no mostrados en los textos y artículos de tribología, donde el tratamiento dado a este modelo resulta ser superficial, desconociendo las limitaciones y la perspectiva que tuvo Archard sobre los aspectos que deberían considerarse en un modelo de desgaste.