Sample records for attenuation physics

  1. The Effect of Physical Loading on Bone Broadband Ultrasound Attenuation

    Institute of Scientific and Technical Information of China (English)

    LIU Cheng-rui; NIU Hai-jun; WANG Ling; FAN Yu-bo; LI De-yu


    Objective: Physical loading changes bone microstructure and may influ-ence quantitative ultrasound (QUS) parameters. This study aims at evaluating the effect of physical loading on bone QUS measurement. Methods:Ten fresh bovine bone specimens were studied, which were scanned by a micro-CT and the density and structure parameters were calculated. The QUS measurement was performed when specimens sub-jected to loading, which changed from 0 to 1,000 N with the step of 100 N. Statistical analysis was performed to evaluate the difference between nBUA measured with and without loading, and the relationship between nBUA and the parameters measured by micro-CT. Results:While the loading exerted on bone lugher than 200 N, the measured nBUA significantly higher than nBUA measured without loading. With the increasing of loading, which exerted on bone, the values of nBUA also increased. A new parameter, the slope of the linearity fitted curve of nBUA values measured under different loading conditions, was introduced to evaluate BMD. The correlation coefficient between the slope and BMD is -0.869 (P=0.001). Conclusion: Physical loading substantially influences bone QUS measurement. QUS measurement performed under loading condition may be a new ultrasound method for osteoporosis diagnosis.

  2. The Physics of the Gas Attenuator for the Linac Coherent Light Source (LCLS)

    Energy Technology Data Exchange (ETDEWEB)

    Ryutov, D.D.; Bionta, R.M.; Hau-Riege, S.P.; Kishiyama, K.I.; McMahon, D.; Roeben, M.D.; Shen, S.; /LLNL, Livermore; Stefan, P.M.; /SLAC


    A systematic assessment of a variety of physics issues affecting the performance of the LCLS X-ray beam attenuator is presented. Detailed analysis of the gas flow in the gas attenuator and in the apertures is performed. A lot of attention is directed towards the gas ionization and heating by intense X-ray pulses. The role of these phenomena in possible deviations of the attenuation coefficient from its 'dialed in' value is evaluated and found small in most cases. Other sources of systematic and statistical errors are also discussed. The regimes where the errors may reach a few percent correspond to the lower X-ray energies (less than 2 keV) and highest beam intensities. Other effects discussed include chemical interaction of the gas with apertures, shock formation in the transonic flow in the apertures of the attenuator, generation of electromagnetic wakes in the gas, and head-to-tail variation of the attenuation caused by the ionization of gas or solid. Possible experimental tests of the consistency of the physics assumptions used in the concept of the gas attenuator are discussed. Interaction of X-rays with the solid attenuator (that will be used at higher X-ray energies, from 2.5 to 8 keV) is considered and thermo-mechanical effects caused by the beam heating are evaluated. Wave-front distortions induced by non-uniform heating of both the solid and the gas are found to be small. An overall conclusion drawn from the analysis presented is that the attenuator will be a reliable and highly versatile device, provided that some caution is exercised in its use for highest beam intensities at lowest X-ray energies.

  3. Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk

    DEFF Research Database (Denmark)

    Oskari Kilpeläinen, Tuomas; Qi, Lu; Brage, Soren


    Background The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA) may attenuate the effect of FTO on obesity risk, other studies have not been able to confirm this interaction. To confirm or refute......>0.8]) and PA were invited to participate, regardless of ethnicity or age of the participants. PA was standardized by categorizing it into a dichotomous variable (physically inactive versus active) in each study. Overall, 25% of adults and 13% of children were categorized as inactive. Interaction analyses were.......20–1.26), but PA attenuated this effect (pinteraction = 0.001). More specifically, the minor allele of rs9939609 increased the odds of obesity less in the physically active group (odds ratio = 1.22/allele, 95% CI 1.19–1.25) than in the inactive group (odds ratio = 1.30/allele, 95% CI 1...

  4. Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality?

    DEFF Research Database (Denmark)

    Ekelund, Ulf; Steene-Johannessen, Jostein; Brown, Wendy J


    and outcome data, provided data on both daily sitting or TV-viewing time and physical activity, and reported effect estimates for all-cause mortality, cardiovascular disease mortality, or breast, colon, and colorectal cancer mortality. We included data from 16 studies, of which 14 were identified through......BACKGROUND: High amounts of sedentary behaviour have been associated with increased risks of several chronic conditions and mortality. However, it is unclear whether physical activity attenuates or even eliminates the detrimental effects of prolonged sitting. We examined the associations...... of sedentary behaviour and physical activity with all-cause mortality. METHODS: We did a systematic review, searching six databases (PubMed, PsycINFO, Embase, Web of Science, Sport Discus, and Scopus) from database inception until October, 2015, for prospective cohort studies that had individual level exposure...

  5. Inflammation During Gestation Induced Spatial Memory and Learning Deficits: Attenuated by Physical Exercise in Juvenile Rats (United States)

    Thangarajan, Rajesh; Rai, Kiranmai. S.; Gopalakrishnan, Sivakumar; Perumal, Vivek


    Background Gestational infections induced inflammation (GIII) is a cause of various postnatal neurological deficits in developing countries. Such intra uterine insults could result in persistent learning-memory disabilities. There are no studies elucidating the efficacy of adolescence exercise on spatial learning- memory abilities of young adult rats pre-exposed to inflammatory insult during fetal life. Aims and Objectives The present study addresses the efficacy of physical (running) exercise during adolescent period in attenuating spatial memory deficits induced by exposure to GIII in rats. Materials and Methods Pregnant Wistar dams were randomly divided into control and lipopolysaccharide (LPS) groups, injected intra peritoneally (i.p) with saline (0.5ml) or lipopolysaccharide (LPS) (0.5mg/kg) on alternate days from gestation day 14 (GD 14) till delivery. After parturition, pups were divided into 3 groups (n=6/group) a) Sham control and LPS group divided into 2 subgroups- b) LPS and c) LPS exercise group. Running exercise was given only to LPS exercise group during postnatal days (PNDs) 30 to 60 (15min/day). Spatial learning and memory performance was assessed by Morris water maze test (MWM), on postnatal day 61 to 67 in all groups. Results Young rats pre-exposed to GIII and subjected to running exercise through juvenile period displayed significant decrease in latency to reach escape platform and spent significant duration in target quadrant in MWM test, compared to age matched LPS group. Results of the current study demonstrated that exercise through juvenile/adolescent period effectively mitigates gestational inflammation-induced cognitive deficits in young adult rats. Conclusion Inflammation during gestation impairs offspring’s spatial memory and learning abilities. Whereas, early postnatal physical exercise attenuates, to higher extent, cognitive impairment resulted from exposure to LPS induced inflammation during intrauterine growth period. PMID:26266117

  6. Long-Term Low Intensity Physical Exercise Attenuates Heart Failure Development in Aging Spontaneously Hypertensive Rats

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    Luana U. Pagan


    Full Text Available Background: Physical exercise is a strategy to control hypertension and attenuate pressure overload-induced cardiac remodeling. The influence of exercise on cardiac remodeling during uncontrolled hypertension is not established. We evaluated the effects of a long-term low intensity aerobic exercise protocol on heart failure (HF development and cardiac remodeling in aging spontaneously hypertensive rats (SHR. Methods: Sixteen month old SHR (n=50 and normotensive Wistar-Kyoto (WKY, n=35 rats were divided into sedentary (SED and exercised (EX groups. Rats exercised in treadmill at 12 m/min, 30 min/day, 5 days/week, for four months. The frequency of HF features was evaluated at euthanasia. Statistical analyses: ANOVA and Tukey or Mann-Whitney, and Goodman test. Results: Despite slightly higher systolic blood pressure, SHR-EX had better functional capacity and lower HF frequency than SHR-SED. Echocardiography and tissue Doppler imaging showed no differences between SHR groups. In SHR-EX, however, left ventricular (LV systolic diameter, larger in SHR-SED than WKY-SED, and endocardial fractional shortening, lower in SHR-SED than WKY-SED, had values between those in WKY-EX and SHR-SED not differing from either group. Myocardial function, assessed in LV papillary muscles, showed improvement in SHR-EX over SHR-SED and WKY-EX. LV myocardial collagen fraction and type I and III collagen gene expression were increased in SHR groups. Myocardial hydroxyproline concentration was lower in SHR-EX than SHR-SED. Lysyl oxidase gene expression was higher in SHR-SED than WKY-SED. Conclusion: Exercise improves functional capacity and reduces decompensated HF in aging SHR independent of elevated arterial pressure. Improvement in functional status is combined with attenuation of LV and myocardial dysfunction and fibrosis.

  7. Does Replacing Sodium Excreted in Sweat Attenuate the Health Benefits of Physical Activity? (United States)

    Turner, Martin J; Avolio, Alberto P


    International guidelines suggest limiting sodium intake to 86-100 mmol/day, but average intake exceeds 150 mmol/day. Participants in physical activities are, however, advised to increase sodium intake before, during and after exercise to ensure euhydration, replace sodium lost in sweat, speed rehydration and maintain performance. A similar range of health benefits is attributable to exercise and to reduction in sodium intake, including reductions in blood pressure (BP) and the increase of BP with age, reduced risk of stroke and other cardiovascular diseases, and reduced risk of osteoporosis and dementia. Sweat typically contains 40-60 mmol/L of sodium, leading to approximately 20-90 mmol of sodium lost in one exercise session with sweat rates of 0.5-1.5 L/h. Reductions in sodium intake of 20-90 mmol/day have been associated with substantial health benefits. Homeostatic systems reduce sweat sodium as low as 3-10 mmol/L to prevent excessive sodium loss. "Salty sweaters" may be individuals with high sodium intake who perpetuate their "salty sweat" condition by continual replacement of sodium excreted in sweat. Studies of prolonged high intensity exercise in hot environments suggest that sodium supplementation is not necessary to prevent hyponatremia during exercise lasting up to 6 hr. We examine the novel hypothesis that sodium excreted in sweat during physical activity offsets a significant fraction of excess dietary sodium, and hence may contribute part of the health benefits of exercise. Replacing sodium lost in sweat during exercise may improve physical performance, but may attenuate the long-term health benefits of exercise.

  8. Attenuation characteristics in eastern Himalaya and southern Tibetan Plateau: An understanding of the physical state of the medium (United States)

    Singh, Sagar; Singh, Chandrani; Biswas, Rahul; Mukhopadhyay, Sagarika; Sahu, Himanshu


    Attenuation characteristics of the crust in the eastern Himalaya and the southern Tibetan Plateau are investigated using high quality data recorded by Himalayan Nepal Tibet Seismic Experiment (HIMNT) during 2001-2003. The present study aims to provide an attenuation model that can address the physical mechanism governing the attenuation characteristics in the underlying medium. We have studied the Coda wave attenuation (Qc) in the single isotropic scattering model hypothesis, S wave attenuation (Qs) by using the coda normalization method and intrinsic (Qi-1) and scattering (Qsc-1) quality factors by the multiple Lapse Time Window Analysis (MLTWA) method under the assumption of multiple isotropic scattering in a 3-D half space within the frequency range 2-12 Hz. All the values of Q exhibit frequency dependent nature for a seismically active area. At all the frequencies intrinsic absorption is predominant compared to scattering attenuation and seismic albedo (B0) are found to be lower than 0.5. The observed discrepancies between the observed and theoretical models can be corroborated by the depth-dependent velocity and attenuation structure as well as the assumption of a uniform distribution of scatterers. Our results correlate well with the existing geo-tectonic model of the area, which may suggest the possible existence of trapped fluids in the crust or its thermal nature. Surprisingly the underlying cause of high attenuation in the crust of eastern Himalaya and southern Tibet makes this region distinct from its adjacent western Himalayan segment. The results are comparable with the other regions reported globally.

  9. Attenuation of Morphine Physical Dependence and Blood Levels of Cortisol by Central and Systemic Administration of Ramelteon in Rat

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    Majid Motaghinejad


    Full Text Available Background: Chronic administration of morphine cause physical dependence but the exact mechanism of this phenomenon remains unclear. The aim of this study is the assessment of systemic and intracerebroventricular (icv administration of ramelteon (a melatonin receptor agonist on morphine physical dependence. Methods: 88 adult male rats were divided into 2 major groups, namely “systematic” and “central” administration of ramelteon. In the first category, systemic administration of ramelteon at various dosages (10, 20, and 40 mg/kg was assessed on dependent animals and withdrawal signs were compared with positive (received morphine and saline as systemic administration, negative control (saline and group under treatment by ramelteon (40 mg/kg groups. In the second category, central administration of ramelteon at various dosages (25, 50, or 100 μg, was assessed on dependent animals and withdrawal signs were compared with the positive control (received morphine and saline as icv and negative control (saline groups, and the group under treatment by ramelteon (50 μg/5 μl/rat. On the test day, all animals received naloxone (3 mg/kg and were observed for withdrawal signs. Total withdrawal score (TWS was also determined. Finally, to evaluate the stress level of dependent rats, blood cortisols were measured. Results: Central administration of ramelteon in all doses and systemic administration in high doses attenuate withdrawal syndrome in comparison with the dependent positive control group (P<0.05. Both central and systemic administrations of ramelteon can attenuate the blood cortisol level in comparison with the dependent positive control group (P<0.05. Conclusion: In conclusion, we found that central administration of ramelteon attenuated morphine withdrawal symptoms and cortisol level as a stress marker.

  10. Physical mechanism of seismic attenuation in a two-phase medium%双相介质中地震波衰减的物理机制

    Institute of Scientific and Technical Information of China (English)



    High-frequency seismic attenuation is conventionally attributed to anelastic absorption. In this paper, I present three studies on high-frequency seismic attenuation and propose that the physical mechanism results from the interference of elastic microscopic multiple scattering waves. First, I propose a new theory on wave propagation in a two-phase medium which is based on the concept that the basic unit for wave propagation is a nano-mass point. As a result of the elasticity variations of pore fluid and rock framework, micro multiple scattering waves would emerge at the wavelength of the seismic waves passing through the two-phase medium and their interference and overlap would generate high-frequency seismic attenuation. Second, I present a study of the frequency response of seismic transmitted waves by modeling thin-layers with thicknesses no larger than pore diameters. Results indicate that high-frequency seismic waves attenuate slightly in a near-surface water zone but decay significantly in a near-surface gas zone. Third, I analyze the seismic attenuation characteristics in near-surface water and gas zones using dual-well shots in the Songliao Basin, and demonstrate that the high-frequency seismic waves attenuate slightly in water zones but in gas zones the 160-1600 Hz propagating waves decay significantly. The seismic attenuation characteristics from field observations coincide with the modeling results. Conclusions drawn from these studies theoretically support seismic attenuation recovery.

  11. Low Intensity Physical Exercise Attenuates Cardiac Remodeling and Myocardial Oxidative Stress and Dysfunction in Diabetic Rats

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    C. Gimenes


    Full Text Available We evaluated the effects of a low intensity aerobic exercise protocol on cardiac remodeling and myocardial function in diabetic rats. Wistar rats were assigned into four groups: sedentary control (C-Sed, exercised control (C-Ex, sedentary diabetes (DM-Sed, and exercised diabetes (DM-Ex. Diabetes was induced by intraperitoneal injection of streptozotocin. Rats exercised for 9 weeks in treadmill at 11 m/min, 18 min/day. Myocardial function was evaluated in left ventricular (LV papillary muscles and oxidative stress in LV tissue. Statistical analysis was given by ANOVA or Kruskal-Wallis. Echocardiogram showed diabetic groups with higher LV diastolic diameter-to-body weight ratio and lower posterior wall shortening velocity than controls. Left atrium diameter was lower in DM-Ex than DM-Sed (C-Sed: 5.73±0.49; C-Ex: 5.67±0.53; DM-Sed: 6.41±0.54; DM-Ex: 5.81±0.50 mm; P<0.05 DM-Sed vs C-Sed and DM-Ex. Papillary muscle function was depressed in DM-Sed compared to C-Sed. Exercise attenuated this change in DM-Ex. Lipid hydroperoxide concentration was higher in DM-Sed than C-Sed and DM-Ex. Catalase and superoxide dismutase activities were lower in diabetics than controls and higher in DM-Ex than DM-Sed. Glutathione peroxidase activity was lower in DM-Sed than C-Sed and DM-Ex. Conclusion. Low intensity exercise attenuates left atrium dilation and myocardial oxidative stress and dysfunction in type 1 diabetic rats.

  12. Superman to the rescue: Simulating physical invulnerability attenuates exclusion-related interpersonal biases. (United States)

    Huang, Julie Y; Ackerman, Joshua M; Bargh, John A


    People cope with social exclusion both by seeking reconnection with familiar individuals and by denigrating unfamiliar and disliked others. These reactions can be seen as adaptive responses in ancestral environments where ostracism exposed people to physical dangers and even death. To the extent that reactions to ostracism evolved to minimize exposure to danger, alleviating these foundational concerns with danger may lessen people's need to cope with exclusion. Three studies demonstrate how a novel physical invulnerability simulation lessens both positive and negative reactions to social exclusion. Study 1 found that simulating physical invulnerability lessened exclusion-triggered negative attitudes toward stigmatized groups, and demonstrated that perceived invulnerability to injury (vs. imperviousness to pain) accounted for this effect. Studies 2 and 3 focused on another facet of social bias by revealing that simulating physical invulnerability lessened the desire for social connection.

  13. Blocking opioids attenuates physical warmth-induced feelings of social connection


    Inagaki, Tristen K.; Irwin, Michael R.; Eisenberger, Naomi I.


    “Heartwarming” social experiences, when one feels interpersonally connected to others, have recently been linked with physical warmth. According to one theory (Panksepp, 1998), “social warmth” and physical warmth may be closely linked because both experiences are supported by similar neurobiological mechanisms, however, the neurochemical substrates underlying this overlap have not been explored. Here, an opioid antagonist, naltrexone, was administered in order to examine the role of opioids, ...

  14. Blocking Opioids Attenuates Physical Warmth-Induced Feelings of Social Connection


    Inagaki, TK; Irwin, MR; Eisenberger, NI


    © 2015 APA, all rights reserved). "Heartwarming" social experiences, when one feels interpersonally connected to others, have recently been linked with physical warmth. According to one theory (Panksepp, 1998), "social warmth" and physical warmth may be closely linked because both experiences are supported by similar neurobiological mechanisms; however, the neurochemical substrates underlying this overlap have not been explored. Here, an opioid antagonist, naltrexone, was administered in orde...

  15. Does a physically active lifestyle attenuate decline in all cognitive functions in old age? (United States)

    Ballesteros, Soledad; Mayas, Julia; Reales, Jose Manuel


    In this study, the performance of a group of 20 physically active older adults was compared with that of a group of 20 sedentary healthy older adults while performing a series of cognitive tasks. These tasks were designed to assess processes that deteriorate most with age, namely executive control (assessed with the Wisconsin Card Sorting Task) and processing speed (simple and choice reaction time tasks). A repetition priming task that does not decline with age, involving attended and unattended picture outlines at encoding, was also included as a control task. The results show that a physically active lifestyle has a positive influence on executive control, processing speed, and controlled processing. As expected, a physically active lifestyle did not enhance repetition priming for attended stimuli, nor did it produce priming for unattended stimuli at encoding. Both groups exhibited robust priming for attended stimuli and no priming for unattended ones. Executive control functions are of vital importance for independent living in old age. These results have practical implications for enhancing the cognitive processes that decline most in old age. Promoting a physically active lifestyle throughout adulthood could significantly reduce the decline of effortful executive control functions in old age.

  16. An Attenuated Total Reflectance Sensor for Copper: An Experiment for Analytical or Physical Chemistry (United States)

    Shtoyko, Tanya; Zudans, Imants; Seliskar, Carl J.; Heineman, William R.; Richardson, John N.


    A sensor experiment which can be applied to advanced undergraduate laboratory course in physical or analytical chemistry is described along with certain concepts like the demonstration of chemical sensing, preparation of thin films on a substrate, microtitration, optical determination of complex ion stoichiometry and isosbestic point. It is seen…

  17. Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice. (United States)

    Dallagnol, Karine Mathilde Campestrini; Remor, Aline Pertile; da Silva, Rodrigo Augusto; Prediger, Rui Daniel; Latini, Alexandra; Aguiar, Aderbal Silva


    Exercise improves mental health and synaptic function in the aged brain. However, the molecular mechanisms involved in exercise-induced healthy brain aging are not well understood. Evidence supports the role of neurogenesis and neurotrophins in exercise-induced neuroplasticity. The gene silencing transcription factor neuronal RE1-silencing transcription factor (REST)/neuron-restrictive silencer factor (NRSF) and an anti-inflammatory role of exercise are also candidate mechanisms. We evaluate the effect of 8weeks of physical activity on running wheels (RW) on motor and depressive-like behavior and hippocampal gene expression of brain-derived neurotrophic factor (BDNF), REST, and interleukins IL-1β and IL-10 of adult and aged C57BL/6 mice. The aged animals exhibited impaired motor function and a depressive-like behavior: decreased mobility in the RW and open field and severe immobility in the tail suspension test. The gene expression of REST, IL-1β, and IL-10 was increased in the hippocampus of aged mice. Physical activity was anxiolytic and antidepressant and improved motor behavior in aged animals. Physical activity also boosted BDNF and REST expression and decreased IL-1β and IL-10 expression in the hippocampus of aged animals. These results support the beneficial role of REST in the aged brain, which can be further enhanced by regular physical activity.

  18. Blocking opioids attenuates physical warmth-induced feelings of social connection. (United States)

    Inagaki, Tristen K; Irwin, Michael R; Eisenberger, Naomi I


    "Heartwarming" social experiences, when one feels interpersonally connected to others, have recently been linked with physical warmth. According to one theory (Panksepp, 1998), "social warmth" and physical warmth may be closely linked because both experiences are supported by similar neurobiological mechanisms; however, the neurochemical substrates underlying this overlap have not been explored. Here, an opioid antagonist, naltrexone, was administered in order to examine the role of opioids, previously shown to alter temperature and social bonding behavior, on perceived thermal intensity, general positive affect, and feelings of social connection from physical warmth. Thirty-one participants took both naltrexone and a placebo and completed a temperature manipulation task (held a warm pack, cold pack, and neutral object) while on each drug. Replicating previous research, holding a warm (vs. a cold or neutral) object increased feelings of social connection. Moreover, blocking opioids reduced this effect. Hence, naltrexone specifically reduced feelings of social connection to holding a warm (vs. neutral) object but not to holding a cold (vs. neutral) object. These results lend further support to the theory that social and physical warmth share neurobiological, opioid receptor dependent mechanisms.

  19. Physical and statistical modeling of attenuation due to atmospheric hydrometeors on free-space optical links at 850 and 1550 nm (United States)

    Grabner, Martin; Kvicera, Vaclav


    Atmospheric hydrometeors such as rain and fog may cause attenuation of an optical signal and degrade the performance of free-space optical (FSO) systems. For efficient design of the FSO links, attenuation characteristics must be predicted by sufficiently reliable models that have been tested on experimental data. A long term experiment on the FSO links operating at 850 and 1550 nm wavelengths is conducted in Prague. The path lengths are 100 and 853 m. Received power fluctuations on the FSO links and relevant meteorological quantities such as rain intensity and liquid water content of fog are measured simultaneously. The relationships between the physical parameters of hydrometeors and path attenuation are analyzed and compared with theoretical relations derived using the Mie scattering theory together with some natural assumptions about the physical properties of scattering particles such as droplet size distribution of different types of hydrometeors. Long term statistics of attenuation are obtained and availability performance of the experimental FSO links is assessed. The method for predicting attenuation statistics based on physical and statistical models is introduced and the errors of the proposed models with respect to measured data are analyzed. The models are compared with the existing empirical relationships derived from other FSO experiments and differences are discussed.

  20. Numerical simulation of a natural gradient tracer experiment for the natural attenuation study: flow and physical transport. (United States)

    Julian, H E; Boggs, J M; Zheng, C; Feehley, C E


    Results are presented for numerical simulations of ground water flow and physical transport associated with a natural gradient tracer experiment conducted within a heterogeneous alluvial aquifer of the Natural Attenuation Study (NATS) site near Columbus, Mississippi. A principal goal of NATS is to evaluate biogeochemical models that predict the rate and extent of natural biodegradation under field conditions. This paper describes the initial phase in the model evaluation process, i.e., calibration of flow and physical transport models that simulate conservative bromide tracer plume evolution during NATS. An initial large-scale flow model (LSM) is developed encompassing the experimental site and surrounding region. This model is subsequently scaled down in telescopic fashion to an intermediate-scale ground water flow model (ISM) covering the tracer-monitoring network, followed by a small-scale transport model (SSM) focused on the small region of hydrocarbon plume migration observed during NATS. The LSM uses inferred depositional features of the site in conjunction with hydraulic conductivity (K) data from aquifer tests and borehole flowmeter tests to establish large-scale K and flow field trends in and around the experimental site. The subsequent ISM incorporates specified flux boundary conditions and large-scale K trends obtained from the calibrated LSM, while preserving small-scale K structure based on some 4000 flowmeter data for solute transport modeling. The configuration of the ISM-predicted potentiometric surface approximates that of the observed surface within a root mean squared error of 0.15 m. The SSM is based on the dual-domain mass-transfer approach. Despite the well-recognized difficulties in modeling solute transport in extremely heterogeneous media as found at the NATS site, the dual-domain model adequately reproduced the observed bromide concentration distributions. Differences in observed and predicted bromide concentration distributions are

  1. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

    Directory of Open Access Journals (Sweden)

    Tuomas O Kilpeläinen


    Full Text Available The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA may attenuate the effect of FTO on obesity risk, other studies have not been able to confirm this interaction. To confirm or refute unambiguously whether PA attenuates the association of FTO with obesity risk, we meta-analyzed data from 45 studies of adults (n = 218,166 and nine studies of children and adolescents (n = 19,268.All studies identified to have data on the FTO rs9939609 variant (or any proxy [r(2>0.8] and PA were invited to participate, regardless of ethnicity or age of the participants. PA was standardized by categorizing it into a dichotomous variable (physically inactive versus active in each study. Overall, 25% of adults and 13% of children were categorized as inactive. Interaction analyses were performed within each study by including the FTO×PA interaction term in an additive model, adjusting for age and sex. Subsequently, random effects meta-analysis was used to pool the interaction terms. In adults, the minor (A- allele of rs9939609 increased the odds of obesity by 1.23-fold/allele (95% CI 1.20-1.26, but PA attenuated this effect (p(interaction  = 0.001. More specifically, the minor allele of rs9939609 increased the odds of obesity less in the physically active group (odds ratio  = 1.22/allele, 95% CI 1.19-1.25 than in the inactive group (odds ratio  = 1.30/allele, 95% CI 1.24-1.36. No such interaction was found in children and adolescents.The association of the FTO risk allele with the odds of obesity is attenuated by 27% in physically active adults, highlighting the importance of PA in particular in those genetically predisposed to obesity.

  2. Physical Principles of the Ultrasonic Attenuation and Backscatter of Soft Tissues: Dependence on the Angle of Propagation and the Physiologic State (United States)

    Mottley, Jack Grigsby

    Quantitative measurements of the interactions of ultrasound with inhomogeneous media serve the dual purposes of elucidating the physics of such interactions and making possible the noninvasive assessment of the state or quality of those materials. One objective of the research presented in this thesis was to provide a physical basis for the application of quantitative techniques to measurements of interactions of ultrasound with an intrinsically interesting inhomogeneous material, soft tissue. A survey of theoretical techniques relevant to the investigation of ultrasonic propagation in inhomogeneous media with both symmetric and non-symmetric inhomogeneities is presented, and the results of calculations based on these theories are compared to experimental measurements. Interactions of ultrasound with several types of soft tissues were investigated under a variety of conditions. Canine myocardium was studied in the normal state, during ischemic insult, after prolonged ischemia, and during reperfusion following transient ischemia. In addition, isolated bullfrog gastrocnemius muscle was studied during relaxation and tetany. The ultrasonic attenuation and backscatter of soft tissues were found to be dependent upon several physiologic and morphologic parameters. In tissues which exhibit regular organization into longitudinal fibers, such as muscles, the attenuation and backscatter were found to be dependent on the direction of propagation relative to the direction of the dominant orientation of the fibers. Specifically, the attenuation was greatest for propagation parallel to the dominant fiber direction, while backscatter was maximum for propagation perpendicular to the fibers. In contrast, these parameters were found to be independent of the angle of insonification in liver, a soft tissue that does not contain regularly oriented fibers. The attenuation and backscatter were affected by the state of contraction of skeletal muscle, with both attenuation and backscatter

  3. Physical exercise prevents short and long-term deficits on aversive and recognition memory and attenuates brain oxidative damage induced by maternal deprivation. (United States)

    Neves, Ben-Hur; Menezes, Jefferson; Souza, Mauren Assis; Mello-Carpes, Pâmela B


    It is known from previous research that physical exercise prevents long-term memory deficits induced by maternal deprivation in rats. But we could not assume similar effects of physical exercise on short-term memory, as short- and long-term memories are known to result from some different memory consolidation processes. Here we demonstrated that, in addition to long-term memory deficit, the short-term memory deficit resultant from maternal deprivation in object recognition and aversive memory tasks is also prevented by physical exercise. Additionally, one of the mechanisms by which the physical exercise influences the memory processes involves its effects attenuating the oxidative damage in the maternal deprived rats' hippocampus and prefrontal cortex.

  4. α-Terpineol attenuates morphine-induced physical dependence and tolerance in mice: role of nitric oxide (United States)

    Parvardeh, Siavash; Moghimi, Mahsa; Eslami, Pegah; Masoudi, Alireza


    Objective(s): Dependence and tolerance to opioid analgesics are major problems limiting their clinical application. α-Terpineol is a monoterpenoid alcohol with neuroprotective effects which is found in several medicinal plants such as Myrtus communis, Laurus nobilis, and Stachys byzantina. It has been shown that some of these medicinal plants such as S. byzantina attenuate dependence and tolerance to morphine. Since α-terpineol is one of the bioactive phytochemical constituent of these medicinal plants, the present study was conducted to investigate the effects of α-terpineol on morphine-induced dependence and tolerance in mice. Materials and Methods: The mice were rendered dependent or tolerant to morphine by a 3-day administration schedule. The hot-plate test and naloxone-induced withdrawal syndrome were used to evaluate tolerance and dependence on morphine, respectively. To investigate a possible role for nitric oxide (NO) in the protective effect of α-terpineol, the NO synthase inhibitor, L-N(G)-nitroarginine methyl ester (L-NAME) and NO precursor, L-arginine, were used. Results: Administration of α-terpineol (5, 10, and 20 mg/kg, IP) significantly decreased the number of jumps in morphine dependent animals. Moreover, α-terpineol (20 and 40 mg/kg, IP) attenuated tolerance to the analgesic effect of morphine. The inhibitory effects of α-terpineol on morphine-induced dependence and tolerance were enhanced by pretreatment with L-NAME (10 mg/kg, IP). However, L-arginine (300 mg/kg, IP) antagonized the protective effects of α-terpineol on dependence and tolerance to morphine. Conclusion: These findings indicate that α-terpineol prevents the development of dependence and tolerance to morphine probably through the influence on NO production. PMID:27081466

  5. Physical plugging does not account for attenuation of capillary leakage by hydroxyethyl starch 130/0.4: a synthetic gel layer model. (United States)

    Tatara, Tsuneo; Itani, Motoi; Sugi, Takashi; Fujita, Kimihiko


    Hydroxyethyl starch (HES) solutions, widely used plasma substitutes, reportedly attenuate capillary leakage via physical plugging of capillary defects. We investigated how 2% HES solutions of different molecular weights (HES(70): 70 kDa, HES(130): 130 kDa, HES(200): 200 kDa, and HES(670): 670 kDa) affect dye release from polyacrylamide gels (PAGs) as a model of endothelial glycocalyx. We assessed dye release from 4% PAG with varying concentrations of albumin [0, 1, 2, 4, and 8% (w/v)] by measuring the change in dye absorbance (ΔAbs) at 5 h for each HES solution. For PAG containing no albumin, ΔAbs for HES(130) was 30% lower than that for HES(70) and HES(200), and 50% lower than that for HES(670). At concentrations of 1-8% albumin, ΔAbs at 5 h with HES(70), HES(130), and HES(200) solutions were almost half that with the HES(670) solution, but no significant differences were noted in ΔAbs at 5 h among HES(70), HES(130), and HES(200) solutions. The inhibition of dye release by HES(670) is likely due to the hindering effect of HES molecules partitioned into gel pores. However, a unique property of HES(130) , including the heavy hydroxyethylation at the C(2) position, may promote specific interactions with PAG and thereby inhibit solute release.

  6. Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation. (United States)

    Dohi, Masafumi; Momose, Wataru; Yamashita, Kazunari; Hakomori, Tadashi; Sato, Shusaku; Noguchi, Shuji; Terada, Katsuhide


    Manufacturing the solid dosage form of an orally administered drug requires lubrication to enhance manufacturability, ensuring that critical quality attributes such as disintegration and dissolution of the drug product are maintained during manufacture. Here, to evaluate lubrication performance during manufacture, we used terahertz attenuated total reflection (THz-ATR) spectroscopy to detect differences in the physical characteristics of the lubricated powder. We applied a simple formulation prepared by blending granulated lactose as filler with magnesium stearate as lubricant. A flat tablet was prepared using the lubricated powder to acquire sharp THz-ATR absorption peaks of the samples. First, we investigated the effects of lubricant concentration and compression pressure on preparation of the tablet and then determined the effect of the pressure applied to samples in contact with the ATR prism on sample absorption amplitude. We focused on the differences in the magnitudes of spectra at the lactose-specific frequency. Second, we conducted the dynamic lubrication process using a 120-L mixer to investigate differences in the magnitudes of absorption corresponding to the lactose-specific frequency during lubrication. In both studies, enriching the lubricated powder with a higher concentration of magnesium stearate or prolonging blending time correlated with higher magnitudes of spectra at the lactose-specific frequency. Further, in the dynamic lubrication study, the wettability and disintegration time of the tablets were compared with the absorption spectra amplitudes at the lactose-specific frequency. We conclude that THz-ATR spectroscopy is useful for detecting differences in densities caused by a change in the physical properties of lactose during lubrication.

  7. Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

    Directory of Open Access Journals (Sweden)

    Shengxu Li

    Full Text Available BACKGROUND: We have previously shown that multiple genetic loci identified by genome-wide association studies (GWAS increase the susceptibility to obesity in a cumulative manner. It is, however, not known whether and to what extent this genetic susceptibility may be attenuated by a physically active lifestyle. We aimed to assess the influence of a physically active lifestyle on the genetic predisposition to obesity in a large population-based study. METHODS AND FINDINGS: We genotyped 12 SNPs in obesity-susceptibility loci in a population-based sample of 20,430 individuals (aged 39-79 y from the European Prospective Investigation of Cancer (EPIC-Norfolk cohort with an average follow-up period of 3.6 y. A genetic predisposition score was calculated for each individual by adding the body mass index (BMI-increasing alleles across the 12 SNPs. Physical activity was assessed using a self-administered questionnaire. Linear and logistic regression models were used to examine main effects of the genetic predisposition score and its interaction with physical activity on BMI/obesity risk and BMI change over time, assuming an additive effect for each additional BMI-increasing allele carried. Each additional BMI-increasing allele was associated with 0.154 (standard error [SE] 0.012 kg/m(2 (p = 6.73 x 10(-37 increase in BMI (equivalent to 445 g in body weight for a person 1.70 m tall. This association was significantly (p(interaction = 0.005 more pronounced in inactive people (0.205 [SE 0.024] kg/m(2 [p = 3.62 x 10(-18; 592 g in weight] than in active people (0.131 [SE 0.014] kg/m(2 [p = 7.97 x 10(-21; 379 g in weight]. Similarly, each additional BMI-increasing allele increased the risk of obesity 1.116-fold (95% confidence interval [CI] 1.093-1.139, p = 3.37 x 10(-26 in the whole population, but significantly (p(interaction = 0.015 more in inactive individuals (odds ratio [OR] = 1.158 [95% CI 1.118-1.199; p = 1.93 x 10(-16] than in active individuals (OR = 1

  8. Planetary Ices Attenuation Properties (United States)

    McCarthy, Christine; Castillo-Rogez, Julie C.

    In this chapter, we review the topic of energy dissipation in the context of icy satellites experiencing tidal forcing. We describe the physics of mechanical dissipation, also known as attenuation, in polycrystalline ice and discuss the history of laboratory methods used to measure and understand it. Because many factors - such as microstructure, composition and defect state - can influence rheological behavior, we review what is known about the mechanisms responsible for attenuation in ice and what can be inferred from the properties of rocks, metals and ceramics. Since attenuation measured in the laboratory must be carefully scaled to geologic time and to planetary conditions in order to provide realistic extrapolation, we discuss various mechanical models that have been used, with varying degrees of success, to describe attenuation as a function of forcing frequency and temperature. We review the literature in which these models have been used to describe dissipation in the moons of Jupiter and Saturn. Finally, we address gaps in our present knowledge of planetary ice attenuation and provide suggestions for future inquiry.


    CERN Multimedia

    P. Sphicas

    There have been three physics meetings since the last CMS week: “physics days” on March 27-29, the Physics/ Trigger week on April 23-27 and the most recent physics days on May 22-24. The main purpose of the March physics days was to finalize the list of “2007 analyses”, i.e. the few topics that the physics groups will concentrate on for the rest of this calendar year. The idea is to carry out a full physics exercise, with CMSSW, for select physics channels which test key features of the physics objects, or represent potential “day 1” physics topics that need to be addressed in advance. The list of these analyses was indeed completed and presented in the plenary meetings. As always, a significant amount of time was also spent in reviewing the status of the physics objects (reconstruction) as well as their usage in the High-Level Trigger (HLT). The major event of the past three months was the first “Physics/Trigger week” in Apri...


    CERN Multimedia

    D. Acosta


    A remarkable amount of progress has been made in Physics since the last CMS Week in June given the exponential growth in the delivered LHC luminosity. The first major milestone was the delivery of a variety of results to the ICHEP international conference held in Paris this July. For this conference, CMS prepared 15 Physics Analysis Summaries on physics objects and 22 Summaries on new and interesting physics measurements that exploited the luminosity recorded by the CMS detector. The challenge was incorporating the largest batch of luminosity that was delivered only days before the conference (300 nb-1 total). The physics covered from this initial running period spanned hadron production measurements, jet production and properties, electroweak vector boson production, and even glimpses of the top quark. Since then, the accumulated integrated luminosity has increased by a factor of more than 100, and all groups have been working tremendously hard on analysing this dataset. The September Physics Week was held ...

  11. Light attenuation on Chlorella vulgaris cells (United States)

    Krol, Tadeusz; Lotocka, Maria


    The laboratory measurements of spectrum of light attenuation on phytoplankton particles i.e. monoculture of unicellural green algae Chlorella vulgaris are presented. The measurements were carried out for alive culture and the cultures subjected to chemical (NaOH) or physical (ultrasounds) modification. The distinct changes in the light attenuation spectrum were a result of modification of the internal cell structures.


    CERN Multimedia

    J. Incandela

    There have been numerous developments in the physics area since the September CMS week. The biggest single event was the Physics/Trigger week in the end of Octo¬ber, whereas in terms of ongoing activities the “2007 analyses” went into high gear. This was in parallel with participation in CSA07 by the physics groups. On the or¬ganizational side, the new conveners of the physics groups have been selected, and a new database for man¬aging physics analyses has been deployed. Physics/Trigger week The second Physics-Trigger week of 2007 took place during the week of October 22-26. The first half of the week was dedicated to working group meetings. The ple¬nary Joint Physics-Trigger meeting took place on Wednesday afternoon and focused on the activities of the new Trigger Studies Group (TSG) and trigger monitoring. Both the Physics and Trigger organizations are now focused on readiness for early data-taking. Thus, early trigger tables and preparations for calibr...


    CERN Multimedia

    P. Sphicas

    The CPT project came to an end in December 2006 and its original scope is now shared among three new areas, namely Computing, Offline and Physics. In the physics area the basic change with respect to the previous system (where the PRS groups were charged with detector and physics object reconstruction and physics analysis) was the split of the detector PRS groups (the old ECAL-egamma, HCAL-jetMET, Tracker-btau and Muons) into two groups each: a Detector Performance Group (DPG) and a Physics Object Group. The DPGs are now led by the Commissioning and Run Coordinator deputy (Darin Acosta) and will appear in the correspond¬ing column in CMS bulletins. On the physics side, the physics object groups are charged with the reconstruction of physics objects, the tuning of the simulation (in collaboration with the DPGs) to reproduce the data, the provision of code for the High-Level Trigger, the optimization of the algorithms involved for the different physics analyses (in collaboration with the analysis gr...

  14. A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease. (United States)

    Modi, Khushbu K; Jana, Arundhati; Ghosh, Supurna; Watson, Richard; Pahan, Kalipada


    Alzheimer's disease (AD), the leading cause of dementia in the aging population, is characterized by the presence of neuritic plaques, neurofibrillary tangles and extensive neuronal apoptosis. Neuritic plaques are mainly composed of aggregates of amyloid-β (Aβ) protein while neurofibrillary tangles are composed of the hyperphosphorylated tau protein. Despite intense investigations, no effective therapy is currently available to halt the progression of this disease. Here, we have undertaken a novel approach to attenuate apoptosis and tau phosphorylation in cultured neuronal cells and in a transgenic animal model of AD. RNS60 is a 0.9% saline solution containing oxygenated nanobubbles that is generated by subjecting normal saline to Taylor-Couette-Poiseuille (TCP) flow under elevated oxygen pressure. In our experiments, fibrillar Aβ1-42, but not the reverse peptide Aβ42-1, induced apoptosis and cell death in human SHSY5Y neuronal cells. RNS60, but not NS (normal saline), RNS10.3 (TCP-modified saline without excess oxygen) or PNS60 (saline containing excess oxygen without TCP modification), attenuated Aβ(1-42)-induced cell death. RNS60 inhibited neuronal cell death via activation of the type 1A phosphatidylinositol-3 (PI-3) kinase-Akt-BAD pathway. Furthermore, RNS60 also decreased Aβ(1-42)-induced tau phosphorylation via (PI-3 kinase-Akt)-mediated inhibition of GSK-3β. Similarly, RNS60 treatment suppressed neuronal apoptosis, attenuated Tau phosphorylation, inhibited glial activation, and reduced the burden of Aβ in the hippocampus and protected memory and learning in 5XFAD transgenic mouse model of AD. Therefore, RNS60 may be a promising pharmaceutical candidate in halting or delaying the progression of AD.

  15. A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease.

    Directory of Open Access Journals (Sweden)

    Khushbu K Modi

    Full Text Available Alzheimer's disease (AD, the leading cause of dementia in the aging population, is characterized by the presence of neuritic plaques, neurofibrillary tangles and extensive neuronal apoptosis. Neuritic plaques are mainly composed of aggregates of amyloid-β (Aβ protein while neurofibrillary tangles are composed of the hyperphosphorylated tau protein. Despite intense investigations, no effective therapy is currently available to halt the progression of this disease. Here, we have undertaken a novel approach to attenuate apoptosis and tau phosphorylation in cultured neuronal cells and in a transgenic animal model of AD. RNS60 is a 0.9% saline solution containing oxygenated nanobubbles that is generated by subjecting normal saline to Taylor-Couette-Poiseuille (TCP flow under elevated oxygen pressure. In our experiments, fibrillar Aβ1-42, but not the reverse peptide Aβ42-1, induced apoptosis and cell death in human SHSY5Y neuronal cells. RNS60, but not NS (normal saline, RNS10.3 (TCP-modified saline without excess oxygen or PNS60 (saline containing excess oxygen without TCP modification, attenuated Aβ(1-42-induced cell death. RNS60 inhibited neuronal cell death via activation of the type 1A phosphatidylinositol-3 (PI-3 kinase-Akt-BAD pathway. Furthermore, RNS60 also decreased Aβ(1-42-induced tau phosphorylation via (PI-3 kinase-Akt-mediated inhibition of GSK-3β. Similarly, RNS60 treatment suppressed neuronal apoptosis, attenuated Tau phosphorylation, inhibited glial activation, and reduced the burden of Aβ in the hippocampus and protected memory and learning in 5XFAD transgenic mouse model of AD. Therefore, RNS60 may be a promising pharmaceutical candidate in halting or delaying the progression of AD.


    CERN Multimedia

    Submitted by

    Physics Week: plenary meeting on physics groups plans for startup (14–15 May 2008) The Physics Objects (POG) and Physics Analysis (PAG) Groups presented their latest developments at the plenary meeting during the Physics Week. In the presentations particular attention was given to startup plans and readiness for data-taking. Many results based on the recent cosmic run were shown. A special Workshop on SUSY, described in a separate section, took place the day before the plenary. At the meeting, we had also two special DPG presentations on “Tracker and Muon alignment with CRAFT” (Ernesto Migliore) and “Calorimeter studies with CRAFT” (Chiara Rovelli). We had also a report from Offline (Andrea Rizzi) and Computing (Markus Klute) on the San Diego Workshop, described elsewhere in this bulletin. Tracking group (Boris Mangano). The level of sophistication of the tracking software increased significantly over the last few months: V0 (K0 and Λ) reconstr...


    CERN Multimedia

    D. Futyan

    A lot has transpired on the “Physics” front since the last CMS Bulletin. The summer was filled with preparations of new Monte Carlo samples based on CMSSW_3, the finalization of all the 10 TeV physics analyses [in total 50 analyses were approved] and the preparations for the Physics Week in Bologna. A couple weeks later, the “October Exercise” commenced and ran through an intense two-week period. The Physics Days in October were packed with a number of topics that are relevant to data taking, in a number of “mini-workshops”: the luminosity measurement, the determination of the beam spot and the measurement of the missing transverse energy (MET) were the three main topics.  Physics Week in Bologna The second physics week in 2009 took place in Bologna, Italy, on the week of Sep 7-11. The aim of the week was to review and establish how ready we are to do physics with the early collisions at the LHC. The agenda of the week was thus pac...


    CERN Multimedia

    D. Futyan

    A lot has transpired on the “Physics” front since the last CMS Bulletin. The summer was filled with preparations of new Monte Carlo samples based on CMSSW_3, the finalization of all the 10 TeV physics analyses [in total 50 analyses were approved] and the preparations for the Physics Week in Bologna. A couple weeks later, the “October Exercise” commenced and ran through an intense two-week period. The Physics Days in October were packed with a number of topics that are relevant to data taking, in a number of “mini-workshops”: the luminosity measurement, the determination of the beam spot and the measurement of the missing transverse energy (MET) were the three main topics.   Physics Week in Bologna The second physics week in 2009 took place in Bologna, Italy, on the week of Sep 7-11. The aim of the week was to review and establish (we hoped) the readiness of CMS to do physics with the early collisions at the LHC. The agenda of the...


    CERN Document Server

    J. Incandela

    The all-plenary format of the CMS week in Cyprus gave the opportunity to the conveners of the physics groups to present the plans of each physics analysis group for tackling early physics analyses. The presentations were complete, so all are encouraged to browse through them on the Web. There is a wealth of information on what is going on, by whom and on what basis and priority. The CMS week was followed by two CMS “physics events”, the ICHEP08 days and the physics days in July. These were two weeks dedicated to either the approval of all the results that would be presented at ICHEP08, or to the review of all the other Monte-Carlo based analyses that were carried out in the context of our preparations for analysis with the early LHC data (the so-called “2008 analyses”). All this was planned in the context of the beginning of a ramp down of these Monte Carlo efforts, in anticipation of data.  The ICHEP days are described below (agenda and talks at: http://indic...


    CERN Multimedia

    Joe Incandela

    There have been two plenary physics meetings since the December CMS week. The year started with two workshops, one on the measurements of the Standard Model necessary for “discovery physics” as well as one on the Physics Analysis Toolkit (PAT). Meanwhile the tail of the “2007 analyses” is going through the last steps of approval. It is expected that by the end of January all analyses will have converted to using the data from CSA07 – which include the effects of miscalibration and misalignment. January Physics Days The first Physics Days of 2008 took place on January 22-24. The first two days were devoted to comprehensive re¬ports from the Detector Performance Groups (DPG) and Physics Objects Groups (POG) on their planning and readiness for early data-taking followed by approvals of several recent studies. Highlights of POG presentations are included below while the activities of the DPGs are covered elsewhere in this bulletin. January 24th was devo...

  1. Physics

    CERN Document Server

    Cullen, Katherine


    Defined as the scientific study of matter and energy, physics explains how all matter behaves. Separated into modern and classical physics, the study attracts both experimental and theoretical physicists. From the discovery of the process of nuclear fission to an explanation of the nature of light, from the theory of special relativity to advancements made in particle physics, this volume profiles 10 pioneers who overcame tremendous odds to make significant breakthroughs in this heavily studied branch of science. Each chapter contains relevant information on the scientist''s childhood, research, discoveries, and lasting contributions to the field and concludes with a chronology and a list of print and Internet references specific to that individual.


    CERN Multimedia

    D. Acosta


    Since the last CMS Week, all physics groups have been extremely active on analyses based on the full 2010 dataset, with most aiming for a preliminary measurement in time for the winter conferences. Nearly 50 analyses were approved in a “marathon” of approval meetings during the first two weeks of March, and the total number of approved analyses reached 90. The diversity of topics is very broad, including precision QCD, Top, and electroweak measurements, the first observation of single Top production at the LHC, the first limits on Higgs production at the LHC including the di-tau final state, and comprehensive searches for new physics in a wide range of topologies (so far all with null results unfortunately). Most of the results are based on the full 2010 pp data sample, which corresponds to 36 pb-1 at √s = 7 TeV. This report can only give a few of the highlights of a very rich physics program, which is listed below by physics group...


    CERN Multimedia

    Chris Hill


    The months that have passed since the last CMS Bulletin have been a very busy and exciting time for CMS physics. We have gone from observing the very first 8TeV collisions produced by the LHC to collecting a dataset of the collisions that already exceeds that recorded in all of 2011. All in just a few months! Meanwhile, the analysis of the 2011 dataset and publication of the subsequent results has continued. These results come from all the PAGs in CMS, including searches for the Higgs boson and other new phenomena, that have set the most stringent limits on an ever increasing number of models of physics beyond the Standard Model including dark matter, Supersymmetry, and TeV-scale gravity scenarios, top-quark physics where CMS has overtaken the Tevatron in the precision of some measurements, and bottom-quark physics where CMS made its first discovery of a new particle, the Ξ*0b baryon (candidate event pictured below). Image 2:  A Ξ*0b candidate event At the same time POGs and PAGs...


    CERN Multimedia

    Guenther Dissertori

    The time period between the last CMS week and this June was one of intense activity with numerous get-together targeted at addressing specific issues on the road to data-taking. The two series of workshops, namely the “En route to discoveries” series and the “Vertical Integration” meetings continued.   The first meeting of the “En route to discoveries” sequence (end 2007) had covered the measurements of the Standard Model signals as necessary prerequisite to any claim of signals beyond the Standard Model. The second meeting took place during the Feb CMS week and concentrated on the commissioning of the Physics Objects, whereas the third occurred during the April Physics Week – and this time the theme was the strategy for key new physics signatures. Both of these workshops are summarized below. The vertical integration meetings also continued, with two DPG-physics get-togethers on jets and missing ET and on electrons and photons. ...

  5. Physical activity attenuates the effect of the FTO genotype on obesity-related traits in European adults: Findings from the Food4Me study (United States)

    Background. The FTO gene harbours the strongest known susceptibility locus for obesity. Studies of the interaction between genetic and environmental factors such as physical activity (PA) could contribute to the understanding of how lifestyle can modulate genetic susceptibility to obesity. In this s...


    CERN Multimedia

    Darin Acosta


    The collisions last year at 900 GeV and 2.36 TeV provided the long anticipated collider data to the CMS physics groups. Quite a lot has been accomplished in a very short time. Although the delivered luminosity was small, CMS was able to publish its first physics paper (with several more in preparation), and commence the commissioning of physics objects for future analyses. Many new performance results have been approved in advance of this CMS Week. One remarkable outcome has been the amazing agreement between out-of-the-box data with simulation at these low energies so early in the commissioning of the experiment. All of this is testament to the hard work and preparation conducted beforehand by many people in CMS. These analyses could not have happened without the dedicated work of the full collaboration on building and commissioning the detector, computing, and software systems combined with the tireless work of many to collect, calibrate and understand the data and our detector. To facilitate the efficien...


    CERN Multimedia

    D. Acosta


    The Physics Groups are actively engaged on analyses of the first data from the LHC at 7 TeV, targeting many results for the ICHEP conference taking place in Paris this summer. The first large batch of physics approvals is scheduled for this CMS Week, to be followed by four more weeks of approvals and analysis updates leading to the start of the conference in July. Several high priority analysis areas were organized into task forces to ensure sufficient coverage from the relevant detector, object, and analysis groups in the preparation of these analyses. Already some results on charged particle correlations and multiplicities in 7 TeV minimum bias collisions have been approved. Only one small detail remains before ICHEP: further integrated luminosity delivered by the LHC! Beyond the Standard Model measurements that can be done with these data, the focus changes to the search for new physics at the TeV scale and for the Higgs boson in the period after ICHEP. Particle Flow The PFT group is focusing on the ...


    CERN Multimedia

    C. Hill


      2012 has started off as a very busy year for the CMS Physics Groups. Planning for the upcoming higher luminosity/higher energy (8 TeV) operation of the LHC and relatively early Rencontres de Moriond are the high-priority activities for the group at the moment. To be ready for the coming 8-TeV data, CMS has made a concerted effort to perform and publish analyses on the 5 fb−1 dataset recorded in 2011. This has resulted in the submission of 16 papers already, including nine on the search for the Higgs boson. In addition, a number of preliminary results on the 2011 dataset have been released to the public. The Exotica and SUSY groups approved several searches for new physics in January, such as searches for W′ and exotic highly ionising particles. These were highlighted at a CERN seminar given on 24th  January. Many more analyses, from all the PAGs, including the newly formed SMP (Standard Model Physics) and FSQ (Forward and Small-x QCD), were approved in February. The ...


    CERN Multimedia

    L. Demortier

    Physics-wise, the CMS week in December was dominated by discussions of the analyses that will be carried out in the “next six months”, i.e. while waiting for the first LHC collisions.  As presented in December, analysis approvals based on Monte Carlo simulation were re-opened, with the caveat that for this work to be helpful to the goals of CMS, it should be carried out using the new software (CMSSW_2_X) and associated samples.  By the end of the week, the goal for the physics groups was set to be the porting of our physics commissioning methods and plans, as well as the early analyses (based an integrated luminosity in the range 10-100pb-1) into this new software. Since December, the large data samples from CMSSW_2_1 were completed. A big effort by the production group gave a significant number of events over the end-of-year break – but also gave out the first samples with the fast simulation. Meanwhile, as mentioned in December, the arrival of 2_2 meant that ...


    CERN Multimedia

    the PAG conveners


    The delivered LHC integrated luminosity of more than 1 inverse femtobarn by summer and more than 5 by the end of 2011 has been a gold mine for the physics groups. With 2011 data, we have submitted or published 14 papers, 7 others are in collaboration-wide review, and 75 Physics Analysis Summaries have been approved already. They add to the 73 papers already published based on the 2010 and 2009 datasets. Highlights from each physics analysis group are described below. Heavy ions Many important results have been obtained from the first lead-ion collision run in 2010. The published measurements include the first ever indications of Υ excited state suppression (PRL synopsis), long-range correlation in PbPb, and track multiplicity over a wide η range. Preliminary results include the first ever measurement of isolated photons (showing no modification), J/ψ suppression including the separation of the non-prompt component, further study of jet fragmentation, nuclear modification factor...


    CERN Multimedia

    C. Hill


      The period since the last CMS Bulletin has been historic for CMS Physics. The pinnacle of our physics programme was an observation of a new particle – a strong candidate for a Higgs boson – which has captured worldwide interest and made a profound impact on the very field of particle physics. At the time of the discovery announcement on 4 July, 2012, prominent signals were observed in the high-resolution H→γγ and H→ZZ(4l) modes. Corroborating excess was observed in the H→W+W– mode as well. The fermionic channel analyses (H→bb, H→ττ), however, yielded less than the Standard Model (SM) expectation. Collectively, the five channels established the signal with a significance of five standard deviations. With the exception of the diphoton channel, these analyses have all been updated in the last months and several new channels have been added. With improved analyses and more than twice the i...


    CERN Multimedia

    C. Hill


    The period since the last CMS bulletin has seen the end of proton collisions at a centre-of-mass energy 8 TeV, a successful proton-lead collision run at 5 TeV/nucleon, as well as a “reference” proton run at 2.76 TeV. With these final LHC Run 1 datasets in hand, CMS Physics Analysis Groups have been busy analysing these data in preparation for the winter conferences. Moreover, despite the fact that the pp run only concluded in mid-December (and there was consequently less time to complete data analyses), CMS again made a strong showing at the Rencontres de Moriond in La Thuile (EW and QCD) where nearly 40 new results were presented. The highlight of these preliminary results was the eagerly anticipated updated studies of the properties of the Higgs boson discovered in July of last year. Meanwhile, preparations for Run 2 and physics performance studies for Phase 1 and Phase 2 upgrade scenarios are ongoing. The Higgs analysis group produced updated analyses on the full Run 1 dataset (~25 f...


    CERN Multimedia

    J. D'Hondt

    The Electroweak and Top Quark Workshop (16-17th of July) A Workshop on Electroweak and Top Quark Physics, dedicated on early measurements, took place on 16th-17th July. We had more than 40 presentations at the Workshop, which was an important milestone for 2007 physics analyses in the EWK and TOP areas. The Standard Model has been tested empirically by many previous experiments. Observables which are nowadays known with high precision will play a major role for data-based CMS calibrations. A typical example is the use of the Z to monitor electron and muon reconstruction in di-lepton inclusive samples. Another example is the use of the W mass as a constraint for di-jets in the kinematic fitting of top-quark events, providing information on the jet energy scale. The predictions of the Standard Model, for what concerns proton collisions at the LHC, are accurate to a level that the production of W/Z and top-quark events can be used as a powerful tool to commission our experiment. On the other hand the measure...


    CERN Multimedia

    C. Hill


    In the period since the last CMS Bulletin, the LHC – and CMS – have entered LS1. During this time, CMS Physics Analysis Groups have performed more than 40 new analyses, many of which are based on the complete 8 TeV dataset delivered by the LHC in 2012 (and in some cases on the full Run 1 dataset). These results were shown at, and well received by, several high-profile conferences in the spring of 2013, including the inaugural meeting of the Large Hadron Collider    Physics Conference (LHCP) in Barcelona, and the 26th International Symposium on Lepton Photon Interactions at High Energies (LP) in San Francisco. In parallel, there have been significant developments in preparations for Run 2 of the LHC and on “future physics” studies for both Phase 1 and Phase 2 upgrades of the CMS detector. The Higgs analysis group produced five new results for LHCP including a new H-to-bb search in VBF production (HIG-13-011), ttH with H to γ&ga...


    CERN Multimedia

    Christopher Hill


    Since the last CMS Bulletin, the CMS Physics Analysis Groups have completed more than 70 new analyses, many of which are based on the complete Run 1 dataset. In parallel the Snowmass whitepaper on projected discovery potential of CMS for HL-LHC has been completed, while the ECFA HL-LHC future physics studies has been summarised in a report and nine published benchmark analyses. Run 1 summary studies on b-tag and jet identification, quark-gluon discrimination and boosted topologies have been documented in BTV-13-001 and JME-13-002/005/006, respectively. The new tracking alignment and performance papers are being prepared for submission as well. The Higgs analysis group produced several new results including the search for ttH with H decaying to ZZ, WW, ττ+bb (HIG-13-019/020) where an excess of ~2.5σ is observed in the like-sign di-muon channel, and new searches for high-mass Higgs bosons (HIG-13-022). Search for invisible Higgs decays have also been performed both using the associ...

  16. Photonic Crystal Fiber Attenuator

    Institute of Scientific and Technical Information of China (English)

    Joo; Beom; Eom; Hokyung; Kim; Jinchae; Kim; Un-Chul; Paek; Byeong; Ha; Lee


    We propose a novel fiber attenuator based on photonic crystal fibers. The difference in the modal field diameters of a conventional single mode fiber and a photonic crystal fiber was used. A variable optical attenuator was also achieved by applying macro-bending on the PCF part of the proposed attenuator

  17. Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats: Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus (United States)

    Leandro, Carol Góis; Fidalgo, Marco; Bento-Santos, Adriano; Falcão-Tebas, Filippe; Vasconcelos, Diogo; Manhães-de-Castro, Raul; Carpinelli, Angelo Rafael; Hirabara, Sandro Massao; Curi, Rui


    The effects of pregestational and gestational low-to-moderate physical training on insulin secretion in undernourished mothers were evaluated. Virgin female Wistar rats were divided into four groups as follows: control (C, n = 5); trained (T, n = 5); low-protein diet (LP, n = 5); trained with a low-protein diet (T + LP, n = 5). Trained rats ran on a treadmill over a period of 4 weeks before mate (5 days week−1 and 60 min day−1, at 65% of VO2max). At pregnancy, the intensity and duration of the exercise were reduced. Low-protein groups were provided with an 8% casein diet, and controls were provided with a 17% casein diet. At third day after delivery, mothers and pups were killed and islets were isolated by collagenase digestion of pancreas and incubated for a further 1 h with medium containing 5.6 or 16.7 mM glucose. T mothers showed increased insulin secretion by isolated islets incubated with 16.7 mM glucose, whereas LP group showed reduced secretion of insulin by isolated islets when compared with both C and LP + T groups. Physical training before and during pregnancy attenuated the effects of a low-protein diet on the secretion of insulin, suggesting a potential role for compensation of insulin resistance and preventing gestational diabetes mellitus. PMID:22927722

  18. Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats: Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Carol Góis Leandro


    Full Text Available The effects of pregestational and gestational low-to-moderate physical training on insulin secretion in undernourished mothers were evaluated. Virgin female Wistar rats were divided into four groups as follows: control (C, n=5; trained (T, n=5; low-protein diet (LP, n=5; trained with a low-protein diet (T + LP, n=5. Trained rats ran on a treadmill over a period of 4 weeks before mate (5 days week−1 and 60 min day−1, at 65% of VO2max. At pregnancy, the intensity and duration of the exercise were reduced. Low-protein groups were provided with an 8% casein diet, and controls were provided with a 17% casein diet. At third day after delivery, mothers and pups were killed and islets were isolated by collagenase digestion of pancreas and incubated for a further 1 h with medium containing 5.6 or 16.7 mM glucose. T mothers showed increased insulin secretion by isolated islets incubated with 16.7 mM glucose, whereas LP group showed reduced secretion of insulin by isolated islets when compared with both C and LP + T groups. Physical training before and during pregnancy attenuated the effects of a low-protein diet on the secretion of insulin, suggesting a potential role for compensation of insulin resistance and preventing gestational diabetes mellitus.

  19. Tracer attenuation in groundwater (United States)

    Cvetkovic, Vladimir


    The self-purifying capacity of aquifers strongly depends on the attenuation of waterborne contaminants, i.e., irreversible loss of contaminant mass on a given scale as a result of coupled transport and transformation processes. A general formulation of tracer attenuation in groundwater is presented. Basic sensitivities of attenuation to macrodispersion and retention are illustrated for a few typical retention mechanisms. Tracer recovery is suggested as an experimental proxy for attenuation. Unique experimental data of tracer recovery in crystalline rock compare favorably with the theoretical model that is based on diffusion-controlled retention. Non-Fickian hydrodynamic transport has potentially a large impact on field-scale attenuation of dissolved contaminants.


    CERN Multimedia



    The main programme of the Physics Week held between 16th and 20th May was a series of topology-oriented workshops on di-leptons, di-photons, inclusive W, and all-hadronic final states. The goal of these workshops was to reach a common understanding for the set of objects (ID, cleaning...), the handling of pile-up, calibration, efficiency and purity determination, as well as to revisit critical common issues such as the trigger. Di-lepton workshop Most analysis groups use a di-lepton trigger or a combination of single and di-lepton triggers in 2011. Some groups need to collect leptons with as low PT as possible with strong isolation and identification requirements as for Higgs into WW at low mass, others with intermediate PT values as in Drell-Yan studies, or high PT as in the Exotica group. Electron and muon reconstruction, identification and isolation, was extensively described in the workshop. For electrons, VBTF selection cuts for low PT and HEEP cuts for high PT were discussed, as well as more complex d...

  1. Landing gear noise attenuation (United States)

    Moe, Jeffrey W. (Inventor); Whitmire, Julia (Inventor); Kwan, Hwa-Wan (Inventor); Abeysinghe, Amal (Inventor)


    A landing gear noise attenuator mitigates noise generated by airframe deployable landing gear. The noise attenuator can have a first position when the landing gear is in its deployed or down position, and a second position when the landing gear is in its up or stowed position. The noise attenuator may be an inflatable fairing that does not compromise limited space constraints associated with landing gear retraction and stowage. A truck fairing mounted under a truck beam can have a compliant edge to allow for non-destructive impingement of a deflected fire during certain conditions.

  2. Nutrient-rich dairy proteins improve appendicular skeletal muscle mass and physical performance, and attenuate the loss of muscle strength in older men and women subjects: a single-blind randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Alemán-Mateo H


    Full Text Available Heliodoro Alemán-Mateo,1 Virginia Ramírez Carreón,1 Liliana Macías,1 Humberto Astiazaran-García,1 Ana Cristina Gallegos-Aguilar,1 José Rogelio Ramos Enríquez2 1Coordinación de Nutrición, Centro de Investigación en Alimentación y Desarrollo, A.C., 2Laboratorio de Análisis Clínicos e Investigación, Departamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Mexico Background: At present, it is unknown whether the use of nutrient-rich dairy proteins improves the markers of sarcopenia syndrome. Therefore, our proposal was to investigate whether ­adding 210 g of ricotta cheese daily would improve skeletal muscle mass, handgrip strength, and ­physical performance in non-sarcopenic older subjects.Subjects and methods: This was a single-blind randomized clinical trial that included two homogeneous, randomized groups of men and women over 60 years of age. Participants in the intervention group were asked to consume their habitual diet but add 210 g of ricotta cheese (IG/HD + RCH, while the control group was instructed to consume only their habitual diet (CG/HD. Basal and 12-week follow-up measurements included appendicular skeletal muscle mass (ASMM by dual-energy X-ray absorptiometry, handgrip strength by a handheld dynamometer, and physical performance using the short physical performance battery (SPPB and the stair-climb power test (SCPT. The main outcomes were relative changes in ASMM, strength, SPPB, and SCPT.Results: ASMM increased in the IG/HD + RCH (0.6±3.5 kg, but decreased in the CG/HD (–1.0±2.6. The relative change between groups was statistically significant (P=0.009. The relative change in strength in both groups was negative, but the loss of muscle strength was more pronounced in CG/HD, though in this regard statistical analysis found only a tendency (P=0.07. The relative change in the balance-test scores was positive for the IG/HD + RCH, while in the CG/HD it was negative, as those individuals had

  3. Mechanisms of geometrical seismic attenuation

    Directory of Open Access Journals (Sweden)

    Igor B. Morozov


    Full Text Available In several recent reports, we have explained the frequency dependence of the apparent seismic quality-factor (Q observed in many studies according to the effects of geometrical attenuation, which was defined as the zero-frequency limit of the temporal attenuation coefficient. In particular, geometrical attenuation was found to be positive for most waves traveling within the lithosphere. Here, we present three theoretical models that illustrate the origin of this geometrical attenuation, and we investigate the causes of its preferential positive values. In addition, we discuss the physical basis and limitations of both the conventional and new attenuation models. For waves in media with slowly varying properties, geometrical attenuation is caused by variations in the wavefront curvature, which can be both positive (for defocusing and negative (for focusing. In media with velocity/density contrasts, incoherent reflectivity leads to geometrical-attenuation coefficients which are proportional to the mean squared reflectivity and are always positive. For «coherent» reflectivity, the geometrical attenuation is approximately zero, and the attenuation process can be described according to the concept of «scattering Q». However, the true meaning of this parameter is in describing the mean reflectivity within the medium, and not that of the traditional resonator quality factor known in mechanics. The general conclusion from these models is that non-zero and often positive levels of geometrical attenuation are common in realistic, heterogeneous media, both observationally and theoretically. When transformed into the conventional Q-factor form, this positive geometrical attenuation leads to Q values that quickly increase with frequency. These predictions show that the positive frequency-dependent Q observed in many datasets might represent artifacts of the transformations of the attenuation coefficients into Q.

  1. Josephson tunnel junction microwave attenuator

    DEFF Research Database (Denmark)

    Koshelets, V. P.; Shitov, S. V.; Shchukin, A. V.


    A new element for superconducting electronic circuitry-a variable attenuator-has been proposed, designed, and successfully tested. The principle of operation is based on the change in the microwave impedance of a superconductor-insulator-superconductor (SIS) Josephson tunnel junction when dc bias...

  2. Compact plasmonic variable optical attenuator

    DEFF Research Database (Denmark)

    Leosson, Kristjan; Rosenzveig, Tiberiu; Hermannsson, Pétur Gordon


    We demonstrate plasmonic nanowire-based thermo-optic variable optical attenuators operating in the 1525-1625 nm wavelength range. The devices have a footprint as low as 1 mm, extinction ratio exceeding 40 dB, driving voltage below 3 V, and full modulation bandwidth of 1 kHz. The polarization...

  3. Dividing of Q factor of viscous and intrinsic attenuation in poroelastic media (United States)

    Ishikura, K.; Mikada, H.; Goto, T.; Takekawa, J.


    Sonic logging has been widely used for many years to understand physical properties of hydrocarbon reservoirs. When gaseous phase exists in the formation fluid, the compressional waves traveling through the formation could be strongly attenuated due to low bulk modulus of gas in the fluid, while the shear waves are not. For acquiring physical properties of fluid in the formation, Biot physics or poroelastic analysis could be the best method. Among the available technologies, quality factors based on the Biot's equation could be used. Although the Biot's theory considers the viscous attenuation induced at the interface between rocks and pore fluids, the intrinsic attenuation caused by the internal friction in the matrix is ignored. In the present study, we investigate how large are the effects of the intrinsic attenuation of compressional waves through the evaluation of the reservoir properties based on the quality factor. We employ a 2D finite-difference scheme to simulate seismic wave propagation in a poroelasic medium. The intrinsic attenuation is included in our model by using the filter of frequency-independent quality factor (constant-Q). We then compare the results compressional waves and shear waves with the intrinsic attenuation in our numerical simulations. Our results clearly show that on compressional and shear waves, the amplitude and phase of the waveforms are strongly affected by the intrinsic attenuation, and we could get only the viscous attenuation by the results of quality factor of compressional wave and shear wave. We conclude that the evaluations of hydrocarbon reservoir require the consideration of the intrinsic attenuation as well as the viscous attenuation predicted by the Biot's theory and also we could get what kind of fluid is contained in the reservoir. The profile of Q factor

  4. Stormwater Attenuation by Green Roofs (United States)

    Sims, A.; O'Carroll, D. M.; Robinson, C. E.; Smart, C. C.


    Innovative municipal stormwater management technologies are urgently required in urban centers. Inadequate stormwater management can lead to excessive flooding, channel erosion, decreased stream baseflows, and degraded water quality. A major source of urban stormwater is unused roof space. Green roofs can be used as a stormwater management tool to reduce roof generated stormwater and generally improve the quality of runoff. With recent legislation in some North American cities, including Toronto, requiring the installation of green roofs on large buildings, research on the effectiveness of green roofs for stormwater management is important. This study aims to assess the hydrologic response of an extensive sedum green roof in London, Ontario, with emphasis on the response to large precipitation events that stress municipal stormwater infrastructure. A green roof rapidly reaches field capacity during large storm events and can show significantly different behavior before and after field capacity. At field capacity a green roof has no capillary storage left for retention of stormwater, but may still be an effective tool to attenuate peak runoff rates by transport through the green roof substrate. The attenuation of green roofs after field capacity is linked to gravity storage, where gravity storage is the water that is temporarily stored and can drain freely over time after field capacity has been established. Stormwater attenuation of a modular experimental green roof is determined from water balance calculations at 1-minute intervals. Data is used to evaluate green roof attenuation and the impact of field capacity on peak flow rates and gravity storage. In addition, a numerical model is used to simulate event based stormwater attenuation. This model is based off of the Richards equation and supporting theory of multiphase flow through porous media.

  5. Ferrite attenuator modulation improves antenna performance (United States)

    Hooks, J. C.; Larson, S. G.; Shorkley, F. H.; Williams, B. T.


    Ferrite attenuator inserted into appropriate waveguide reduces the gain of the antenna element which is causing interference. Modulating the ferrite attenuator to change the antenna gain at the receive frequency permits ground tracking until the antenna is no longer needed.


    Energy Technology Data Exchange (ETDEWEB)

    Vangelas, K; W. H. Albright, W; E. S. Becvar, E; C. H. Benson, C; T. O. Early, T; E. Hood, E; P. M. Jardine, P; M. Lorah, M; E. Majche, E; D. Major, D; W. J. Waugh, W; G. Wein, G; O. R. West, O


    In 2003 the US Department of Energy (DOE) embarked on a project to explore an innovative approach to remediation of subsurface contaminant plumes that focused on introducing mechanisms for augmenting natural attenuation to achieve site closure. Termed enhanced attenuation (EA), this approach has drawn its inspiration from the concept of monitored natural attenuation (MNA).

  7. Chlorine signal attenuation in concrete. (United States)

    Naqvi, A A; Maslehuddin, M; ur-Rehman, Khateeb; Al-Amoudi, O S B


    The intensity of prompt gamma-ray was measured at various depths from chlorine-contaminated silica fume (SF) concrete slab concrete specimens using portable neutron generator-based prompt gamma-ray setup. The intensity of 6.11MeV chloride gamma-rays was measured from the chloride contaminated slab at distance of 15.25, 20.25, 25.25, 30.25 and 35.25cm from neutron target in a SF cement concrete slab specimens. Due to attenuation of thermal neutron flux and emitted gamma-ray intensity in SF cement concrete at various depths, the measured intensity of chlorine gamma-rays decreases non-linearly with increasing depth in concrete. A good agreement was noted between the experimental results and the results of Monte Carlo simulation. This study has provided useful experimental data for evaluating the chloride contamination in the SF concrete utilizing gamma-ray attenuation method.

  8. Novel MEMS variable optical attenuator

    Institute of Scientific and Technical Information of China (English)

    Maosong Wu(吴茂松); Chunsheng Yang(杨春生); Xinhui Mao(茅昕辉); Xiaolin Zhao(赵小林); Bingchu Cai(蔡炳初)


    A novel MEMS variable optical attenuator (VOA), which has completely different attenuation mechanismfrom those in literatures, is proposed and demonstrated in this paper. The basic operation principle is thatthe optical power coupled between two initially aligned single-mode fibers will be continuously attenuatedwhile the end of one of the fibers is deflected from the initial position. A micromachined solenoid typeinductor with a U-shaped permalloy magnetic core is used to attract the deflectable fiber that has apermalloy coat on its end. To fabricate the multi-layer three-dimensional inductive component, a newUV-LIGA process for thick photoresists is developed, combining advantages of both SU-8 and AZ-4000series photoresists. The inductive component is approximately 1.7 mm× 1.3 mm×50μm in size and has alow resistance value (~ 2.1Ω). The whole size of the VOA before packaging is 30 mm×2 mm×0.6 mm.The first prototype shows less then 3-dB insertion loss at 0-dB attenuation and nearly 40-dB attenuationrange with less than 20 mW electrical input power at wavelength 1550 nm.

  9. Q value of anelastic S-wave attenuation in Yunnan region

    Institute of Scientific and Technical Information of China (English)

    SU You-jin; LIU Jie; ZHENG Si-hua; LIU Li-fang; FU Hong; XU Yan


    @@ The study of seismic attenuation property is a major subject in seismology. Seismic waves recorded by seismic stations (seismographs) contain source effect, seismic wave propagation effect, site response of seismic stations and instrumental response. The path effect of seismic wave propagation, site response of seismic stations and instrumental response must be taken out in the study of source property with seismic data. The path effect of seismic wave propagation (seismic attenuation) involves an important influential factor, the anelastic attenuation of medium, which is measured with quality factor Q, apart from geometric attenuation with the distance. As a basic physical parameter of the Earth medium, Q value is essential for quantitative study of earthquakes and source property (e.g. determination of source parameters), which is widely used in earthquake source physics and engineering seismology.

  10. A longitudinal study of emotional adjustment, quality of life and adaptive function in attenuated MPS II

    Directory of Open Access Journals (Sweden)

    Elsa G. Shapiro


    Conclusions: Attenuated MPS II patients have increasing somatic disease burden and poor physical quality of life as they develop as well as decreasing self-esteem and sense of adequacy. Psychosocial quality of life, adaptive skills, and attention improve. Recognition of and intervention around these issues will be beneficial to MPS II attenuated patients who have the resources to use such assistance to improve their long-term outcomes.

  11. Imaging Rayleigh wave attenuation with USArray (United States)

    Bao, Xueyang; Dalton, Colleen A.; Jin, Ge; Gaherty, James B.; Shen, Yang


    The EarthScope USArray provides an opportunity to obtain detailed images of the continental upper mantle at an unprecedented scale. The majority of mantle models derived from USArray data to date contain spatial variations in seismic-wave speed; however, in many cases these data sets do not by themselves allow a non-unique interpretation. Joint interpretation of seismic attenuation and velocity models can improve upon the interpretations based only on velocity and provide important constraints on the temperature, composition, melt content, and volatile content of the mantle. The surface wave amplitudes that constrain upper-mantle attenuation are sensitive to factors in addition to attenuation, including the earthquake source excitation, focusing and defocusing by elastic structure, and local site amplification. Because of the difficulty of isolating attenuation from these other factors, little is known about the attenuation structure of the North American upper mantle. In this study, Rayleigh wave traveltime and amplitude in the period range 25-100 s are measured using an interstation cross-correlation technique, which takes advantage of waveform similarity at nearby stations. Several estimates of Rayleigh wave attenuation and site amplification are generated at each period, using different approaches to separate the effects of attenuation and local site amplification on amplitude. It is assumed that focusing and defocusing effects can be described by the Laplacian of the traveltime field. All approaches identify the same large-scale patterns in attenuation, including areas where the attenuation values are likely contaminated by unmodelled focusing and defocusing effects. Regionally averaged attenuation maps are constructed after removal of the contaminated attenuation values, and the variations in intrinsic shear attenuation that are suggested by these Rayleigh wave attenuation maps are explored.

  12. Forward- vs. Inverse Problems in Modeling Seismic Attenuation (United States)

    Morozov, I. B.


    Seismic attenuation is an important property of wave propagation used in numerous applications. However, the attenuation is also a complex phenomenon, and it is important to differentiate between its two typical uses: 1) in forward problems, to model the amplitudes and spectral contents of waves required for hazard assessment and geotechnical engineering, and 2) in inverse problems, to determine the physical properties of the subsurface. In the forward-problem sense, the attenuation is successfully characterized in terms of empirical parameters of geometric spreading, radiation patterns, scattering amplitudes, t-star, alpha, kappa, or Q. Arguably, the predicted energy losses can be correct even if the underlying attenuation model is phenomenological and not sufficiently based on physics. An example of such phenomenological model is the viscoelasticity based on the correspondence principle and the Q-factor assigned to the material. By contrast, when used to invert for in situ material properties, models addressing the specific physics are required. In many studies (including in this session), a Q-factor is interpreted as a property of a point within the subsurface; however this property is only phenomenological and may be physically insufficient or inconsistent. For example, the bulk or shear Q at the same point can be different when evaluated from different wave modes. The cases of frequency-dependent Q are particularly prone of ambiguities such as trade-off with the assumed background geometric spreading. To rigorously characterize the in situ material properties responsible for seismic-wave attenuation, it is insufficient to only focus on the seismic energy loss. Mechanical models of the material need to be considered. Such models can be constructed by using Lagrangian mechanics. These models should likely contain no Q but will be based on parameters of microstructure such as heterogeneity, fractures, or fluids. I illustrate several such models based on viscosity

  13. Magnetoelectric Composite Based Microwave Attenuator (United States)

    Tatarenko, A. S.; Srinivasan, G.


    Ferrite-ferroelectric composites are magnetoelectric (ME) due to their response to elastic and electromagnetic force fields. The ME composites are characterized by tensor permittivity, permeability and ME susceptibility. The unique combination of magnetic, electrical, and ME interactions, therefore, opens up the possibility of electric field tunable ferromagnetic resonance (FMR) based devices [1]. Here we discuss an ME attenuator operating at 9.3 GHz based on FMR in a layered sample consisting of lead magnesium niobate-lead titanate bonded to yttrium iron garnet (YIG) film on a gadolinium gallium garnet substrate. Electrical tuning is realized with the application of a control voltage due to ME effect; the shift is 0-15 Oe as E is increased from 0 to 3 kV/cm. If the attenuator is operated at FMR, the corresponding insertion loss will range from 25 dB to 2 dB. 1. S. Shastry and G. Srinivasan, M.I. Bichurin, V.M. Petrov, A.S. Tatarenko. Phys. Rev. B, 70 064416 (2004). - supported by grants the grants from the National Science Foundation (DMR-0302254), from Russian Ministry of Education (Å02-3.4-278) and from Universities of Russia Foundation (UNR 01.01.026).

  14. Nutrient attenuation in rivers and streams, Puget Sound Basin, Washington (United States)

    Sheibley, Rich W.; Konrad, Christopher P.; Black, Robert W.


    Nutrients such as nitrogen and phosphorus are important for aquatic ecosystem health. Excessive amounts of nutrients, however, can make aquatic ecosystems harmful for biota because enhanced growth and decay cycles of aquatic algae can reduce dissolved oxygen in the water. In Puget Sound marine waters, low dissolved oxygen concentrations are observed in a number of marine nearshore areas, and nutrients have been identified as a major stressor to the local ecosystem. Delivery of nutrients from major rivers in the Puget Sound Basin to the marine environment can be large. Therefore, it is important to identify factors related to how nutrients are retained (attenuated) within streams and rivers in the Puget Sound Basin. Physical, chemical, and biological factors related to nutrient attenuation were identified through a review of related scientific literature.

  15. Attenuation map reconstruction from TOF PET data

    CERN Document Server

    Yang, Qingsong; Wang, Ge


    To reconstruct a radioactive tracer distribution with positron emission tomography (PET), the background attenuation correction is needed to eliminate image artifacts. Recent research shows that time-of-flight (TOF) PET data determine the attenuation sinogram up to a constant, and its gradient can be computed using an analytic algorithm. In this paper, we study a direct estimation of the sinogram only from TOF PET data. First, the gradient of the attenuation sinogram is estimated using the aforementioned algorithm. Then, a relationship is established to link the differential attenuation sinogram and the underlying attenuation background. Finally, an iterative algorithm is designed to determine the attenuation sinogram accurately and stably. A 2D numerical simulation study is conducted to verify the correctness of our proposed approach.

  16. Cement-based materials' characterization using ultrasonic attenuation (United States)

    Punurai, Wonsiri

    The quantitative nondestructive evaluation (NDE) of cement-based materials is a critical area of research that is leading to advances in the health monitoring and condition assessment of the civil infrastructure. Ultrasonic NDE has been implemented with varying levels of success to characterize cement-based materials with complex microstructure and damage. A major issue with the application of ultrasonic techniques to characterize cement-based materials is their inherent inhomogeneity at multiple length scales. Ultrasonic waves propagating in these materials exhibit a high degree of attenuation losses, making quantitative interpretations difficult. Physically, these attenuation losses are a combination of internal friction in a viscoelastic material (ultrasonic absorption), and the scattering losses due to the material heterogeneity. The objective of this research is to use ultrasonic attenuation to characterize the microstructure of heterogeneous cement-based materials. The study considers a real, but simplified cement-based material, cement paste---a common bonding matrix of all cement-based composites. Cement paste consists of Portland cement and water but does not include aggregates. First, this research presents the findings of a theoretical study that uses a set of existing acoustics models to quantify the scattered ultrasonic wavefield from a known distribution of entrained air voids. These attenuation results are then coupled with experimental measurements to develop an inversion procedure that directly predicts the size and volume fraction of entrained air voids in a cement paste specimen. Optical studies verify the accuracy of the proposed inversion scheme. These results demonstrate the effectiveness of using attenuation to measure the average size, volume fraction of entrained air voids and the existence of additional larger entrapped air voids in hardened cement paste. Finally, coherent and diffuse ultrasonic waves are used to develop a direct

  17. Optimal ultrasonic array focusing in attenuative media. (United States)

    Ganguli, A; Gao, R X; Liang, K; Jundt, J


    This paper presents a parametric study on the efficiency of ultrasound focusing in an attenuative medium, using phased arrays. Specifically, an analytical model of ultrasound wave focusing in a homogeneous, isotropic and attenuative fluid with point sources is presented. Calculations based on the model have shown that in an attenuative medium, an optimum frequency exists for the best focusing performance for a particular size of aperture and focal distance. The effect of different f numbers on the focusing performance in the attenuative medium is further investigated. The information obtained from the analytical model provides insights into the design and installation of a phased transducer array for energy efficient wave focusing.

  18. Detailed Study of Seismic Wave Attenuation in Carbonate Rocks: Application on Abu Dhabi Oil Fields (United States)

    Bouchaala, F.; Ali, M. Y.; Matsushima, J.


    Seismic wave attenuation is a promising attribute for the petroleum exploration, thanks to its high sensitivity to physical properties of subsurface. It can be used to enhance the seismic imaging and improve the geophysical interpretation which is crucial for reservoir characterization. However getting an accurate attenuation profile is not an easy task, this is due to complex mechanism of this parameter, although that many studies were carried out to understand it. The degree of difficulty increases for the media composed of carbonate rocks, known to be highly heterogeneous and with complex lithology. That is why few attenuation studies were done successfully in carbonate rocks. The main objectives of this study are, Getting an accurate and high resolution attenuation profiles from several oil fields. The resolution is very important target for us, because many reservoirs in Abu Dhabi oil fields are tight.Separation between different modes of wave attenuation (scattering and intrinsic attenuations).Correlation between the attenuation profiles and other logs (Porosity, resistivity, oil saturation…), in order to establish a relationship which can be used to detect the reservoir properties from the attenuation profiles.Comparison of attenuation estimated from VSP and sonic waveforms. Provide spatial distribution of attenuation in Abu Dhabi oil fields.To reach these objectives we implemented a robust processing flow and new methodology to estimate the attenuation from the downgoing waves of the compressional VSP data and waveforms acquired from several wells drilled in Abu Dhabi. The subsurface geology of this area is primarily composed of carbonate rocks and it is known to be highly fractured which complicates more the situation, then we separated successfully the intrinsic attenuation from the scattering. The results show that the scattering is significant and cannot be ignored. We found also a very interesting correlation between the attenuation profiles and the

  19. Physics for radiation protection

    CERN Document Server

    Martin, James E


    A much-needed working resource for health physicists and other radiation protection professionals, this volume presents clear, thorough, up-to-date explanations of the basic physics necessary to address real-world problems in radiation protection. Designed for readers with limited as well as basic science backgrounds, Physics for Radiation Protection emphasizes applied concepts and carefully illustrates all topics through examples as well as practice problems. Physics for Radiation Protection draws substantially on current resource data available for health physics use, providing decay schemes and emission energies for approximately 100 of the most common radionuclides encountered by practitioners. Excerpts of the Chart of the Nuclides, activation cross sections, fission yields, fission-product chains, photon attenuation coefficients, and nuclear masses are also provided.

  20. Wideband, 50 dB Attenuation Range Liquid Crystal Based Variable Optical Attenuator

    Institute of Scientific and Technical Information of China (English)

    J.J.; Pan; Henry; He; Eric; Zhang


    A compact variable optical attenuator, covering C and L bands with over 50 dB attenuation range, is realized using a single liquid crystal cell with a tilted fused silica coating compensating the cell's small residual birefringence.

  1. Ultrasonic attenuation in cuprate superconductors

    Indian Academy of Sciences (India)

    T Gupta; D M Gaitonde


    We calculate the longitudinal ultrasonic attenuation rate (UAR) in clean d-wave superconductors in the Meissner and the mixed phases. In the Meissner phase we calculate the contribution of previously ignored processes involving the excitation of a pair of quasi-holes or quasi-particles. There is a contribution ∝ in the regime B ≪ F ≪ 0 and a contribution ∝ 1/ in the regime F ≪ B ≪ 0. We find that these contributions to the UAR are large and cannot be ignored. In the mixed phase, using a semi-classical description, we calculate the electronic quasi-particle contribution to the UAR which at very low , has a independent term proportional to $\\sqrt{H}$.

  2. Geophysical imaging of subsurface structures in volcanic area by seismic attenuation profiling (United States)

    Tsuru, Tetsuro; No, Tetsuo; Fujie, Gou


    Geophysical imaging by using attenuation property of multichannel seismic reflection data was tested to map spatial variation of physical properties of rocks in a volcanic area. The study area is located around Miyakejima volcanic island, where an intensive earthquake swarm was observed associated with 2000 Miyakejima eruption. Seismic reflection survey was conducted five months after the swarm initiation in order to clarify crustal structure around the hypocenters of the swarm activity. However, the resulting seismic reflection profiles were unable to provide significant information of deep structures around the hypocenters. The authors newly applied a seismic attribute method that focused seismic attenuation instead of reflectivity to the volcanic area, and designed this paper to assess the applicability of this method to subsurface structural studies in poorly reflective volcanic areas. Resulting seismic attenuation profiles successfully figured out attenuation structures around the Miyakejima volcanic island. Interestingly, a remarkable high-attenuation zone was detected between Miyakejima and Kozushima islands, being well correlated with the hypocenter distribution of the earthquake swarm in 2000. The high-attenuation zone is interpreted as a fractured area that was developed by magma activity responsible for the earthquake swarms that have been repeatedly occurring there. The present study can be one example showing the applicability of seismic attenuation profiling in a volcanic area. [Figure not available: see fulltext. Caption: .

  3. An ice-sheet-wide framework for englacial attenuation from ice-penetrating radar data (United States)

    Jordan, T. M.; Bamber, J. L.; Williams, C. N.; Paden, J. D.; Siegert, M. J.; Huybrechts, P.; Gagliardini, O.; Gillet-Chaulet, F.


    Radar inference of the bulk properties of glacier beds, most notably identifying basal melting, is, in general, derived from the basal reflection coefficient. On the scale of an ice sheet, unambiguous determination of basal reflection is primarily limited by uncertainty in the englacial attenuation of the radio wave, which is an Arrhenius function of temperature. Existing bed-returned power algorithms for deriving attenuation assume that the attenuation rate is regionally constant, which is not feasible at an ice-sheet-wide scale. Here we introduce a new semi-empirical framework for deriving englacial attenuation, and, to demonstrate its efficacy, we apply it to the Greenland Ice Sheet. A central feature is the use of a prior Arrhenius temperature model to estimate the spatial variation in englacial attenuation as a first guess input for the radar algorithm. We demonstrate regions of solution convergence for two input temperature fields and for independently analysed field campaigns. The coverage achieved is a trade-off with uncertainty and we propose that the algorithm can be "tuned" for discrimination of basal melt (attenuation loss uncertainty ˜ 5 dB). This is supported by our physically realistic ( ˜ 20 dB) range for the basal reflection coefficient. Finally, we show that the attenuation solution can be used to predict the temperature bias of thermomechanical ice sheet models and is in agreement with known model temperature biases at the Dye 3 ice core.


    Directory of Open Access Journals (Sweden)

    Eduardo Fonseca-Pedrero


    Full Text Available Psychotic syndrome includes several devastating mental disorders characterized by a rupture of higher mental functions. The signs and symptoms of psychosis begin in adolescence or early adulthood and usually begin gradually and progress over time. Attenuated psychosis syndrome is a new DSM-5 diagnostic proposal which deals with identifying people at high-risk mental state (ARMS/UHR which may be a predictor of conversion to psychosis. The potential benefit would be that if psychotic disorder is treated more effectively in its early stages, it could produce a lasting beneficial effect that probably could not be achieved with later intervention. This syndrome has generated intense discussion in specialized scientific and professional forums, crisscrossing arguments in favor and against its inclusion. HRMS is preferentially evaluated in the adolescent or young adult population. HRMS evolution is associated with a higher rate of transition toward nonaffective psychosis, although it can evolve toward other mental disorders, remain stable or remit over time. Empirical evidence shows that early intervention seems to have a certain beneficial effect, although for now the results are still insufficient and contradictory. The lack of specificity of symptoms in predicting psychosis, presence of certain limitations (e.g., stigmatization, results found in early interventions and lack of empirical evidence, have led to include the attenuated psychosis syndrome in the DSM-5 Appendix III. The main benefits and limitations of including this supposed category, possible lessons learned from this type of study and future lines of action are discussed in the light of these findings.

  5. Attenuation characteristics of a light attenuator combined by polarizers with different extinction ratios

    Institute of Scientific and Technical Information of China (English)

    Huang Chong; Deng Peng; Zhao Shuang; Chen Hai-Qing


    This paper deals with a systematical analysis and an algorithm of attenuation characteristics of a light attenuator combined by n pieces of polarizers(n-LACP)whose extinction ratios are different from each other.The attenuation ratio expression of a two-LACP is deduced. We find that the monotonic attenuation interval depends on the first polarizer and that the attenuation range depends on the second one.For the three-LACP,a method for obtaining a monotonic attenuation interval is proposed.Moreover,the attenuation ratio expression is demonstrated.Analysis and experiment show that when the initial status of the three-LACP is at the maximum output,if the second or third polarizer rotates alone,the minimum attenuation ratios can reach K2-1and K3-1,respectively,and if the first polarizer rotates,a minimum attenuation ratio of K2-1K3-1can be obtained(K1,K2 and K3 represent the extinction ratios of the three polarizers in turn).Furthermore,the attenuation ratio expression of n-LACP and the relevant attenuation characteristics are proposed.The minimum attenuation ratio of an n-LACP is(K2K3...Kn)-1.

  6. Attenuation of concentration fluctuations of water vapor and other trace gases in turbulent tube flow

    DEFF Research Database (Denmark)

    Massman, W.J.; Ibrom, Andreas


    Recent studies with closed-path eddy covariance (EC) systems have indicated that the attenuation of fluctuations of water vapor concentration is dependent upon ambient relative humidity, presumably due to sorption/desorption of water molecules at the interior surface of the tube. Previous studies...... of EC-related tube attenuation effects have either not considered this issue at all or have only examined it superficially. Nonetheless, the attenuation of water vapor fluctuations is clearly much greater than might be expected from a passive tracer in turbulent tube flow. This study reexamines...... the turbulent tube flow issue for both passive and sorbing tracers with the intent of developing a physically-based semi-empirical model that describes the attenuation associated with water vapor fluctuations. Toward this end, we develop a new model of tube flow dynamics (radial profiles of the turbulent...

  7. Exact equations for soil particle-size analysis by gamma-ray attenuation

    Energy Technology Data Exchange (ETDEWEB)

    Elias, Elimoel Abraao; Bacchi, Osny Oliveira Santos; Reichardt, Klaus [Centro de Energia Nuclear na Agricultura (CENA), Piracicaba, SP (Brazil). Lab, de Fisica do Solo


    Soil particle-size analysis by gamma-ray attenuation was first suggested in 1992 and improved in 1997 by diminishing the measurement time and adapting it for automation. It is here demonstrated that when the mass attenuation coefficient {mu}{sub w} and the density D{sub w} are replaced by {mu}{sub s} and D{sub s} (where the subscripts w and s stand for water and solution) in the approximate equations used to estimate the concentration of suspended particles, they become exact. The demonstration is based by treating the dispersant and water solution as one single medium, instead of treating them as two media In this way, six variables are reduced to only three. Physical considerations suggest that the precision in this analysis could be improved if other types of solutions and of photon energies would be used, so that the attenuation by the particles would differ more significantly from the attenuation by the solution. (author)

  8. Monitoring changes of optical attenuation coefficients of acupuncture points during laser acupuncture by optical coherence tomography (United States)

    Huang, Yimei; Yang, Hongqin; Wang, Yuhua; Zheng, Liqin; Xie, Shusen


    The physical properties of acupuncture point were important to discover the mechanism of acupuncture meridian. In this paper, we used an optical coherence tomography to monitor in vivo the changes of optical attenuation coefficients of Hegu acupuncture point and non-acupuncture point during laser irradiation on Yangxi acupuncture point. The optical attenuation coefficients of Hegu acupuncture point and non-acupuncture point were obtained by fitting the raw data according to the Beer-Lambert's law. The experimental results showed that the optical attenuation coefficient of Hegu acupuncture point decreased during the laser acupuncture, in contrast to a barely changed result in that of non-acupuncture point. The significant change of optical attenuation coefficient of Hegu acupuncture point indicated that there was a correlation between Hegu and Yangxi acupuncture points to some extent.


    Institute of Scientific and Technical Information of China (English)

    BI Weiping; MU Xiaowu; SUN Yuqiang


    In present paper, the disturbance attenuation problem of uncertain nonlinear cascaded systems is studied. Based on the adding one power integrator technique and recursive design, a feedback controller that solves the disturbance attenuation problem is constructed for uncertain nonlinear cascaded systems with internal stability.

  10. Attenuation coefficients for water quality trading. (United States)

    Keller, Arturo A; Chen, Xiaoli; Fox, Jessica; Fulda, Matt; Dorsey, Rebecca; Seapy, Briana; Glenday, Julia; Bray, Erin


    Water quality trading has been proposed as a cost-effective approach for reducing nutrient loads through credit generation from agricultural or point source reductions sold to buyers facing costly options. We present a systematic approach to determine attenuation coefficients and their uncertainty. Using a process-based model, we determine attenuation with safety margins at many watersheds for total nitrogen (TN) and total phosphorus (TP) loads as they transport from point of load reduction to the credit buyer. TN and TP in-stream attenuation generally increases with decreasing mean river flow; smaller rivers in the modeled region of the Ohio River Basin had TN attenuation factors per km, including safety margins, of 0.19-1.6%, medium rivers of 0.14-1.2%, large rivers of 0.13-1.1%, and very large rivers of 0.04-0.42%. Attenuation in ditches transporting nutrients from farms to receiving rivers is 0.4%/km for TN, while for TP attenuation in ditches can be up to 2%/km. A 95 percentile safety margin of 30-40% for TN and 6-10% for TP, applied to the attenuation per km factors, was determined from the in-stream sensitivity of load reductions to watershed model parameters. For perspective, over 50 km a 1% per km factor would result in 50% attenuation = 2:1 trading ratio.

  11. Ultrasound fields in an attenuating medium

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Gandhi,, D; O'Brien,, W.D., Jr.


    Ultrasound fields propagating in tissue will undergo changes in shape not only due to diffraction, but also due to the frequency dependent attenuation. Linear fields can be fairly well predicted for a non-attenuating medium like water by using the Tupholme-Stepanishen method for calculating...... the spatial impulse response, whereas the field cannot readily be found for an attenuating medium. In this paper we present a simulation program capable of calculating the field in a homogeneous attenuating medium. The program splits the aperture into rectangles and uses a far-field approximation for each...... of the rectangles and sums all contributions to arrive at the spatial impulse response for the aperture and field point. This approach makes it possible to model all transducer apertures, and the program can readily calculate the emitted, pulse-echo and continuous wave field. Attenuation is included by splitting...

  12. Natural attenuation of hydrocarbon polluted soils in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez-Linares, L.; Rojas-Avelizapa, N.; Roldan-Carrillo, T.; Islas-Ramirez, M.


    Crude oil and hydrocarbon by-proudcts are the most common pollutants in Mexico. In the last years, the two terms, contamination and remediation have being re-defined; also, based on both the scientific advancement and the human risk, the sustentability of remediation technologies and the definition of cleaning levels has been taking place. In this context, the Natural Attenuation of soils is a viable and low cost remediation choice, defined as the degradation of organic compounds without artificial stimulation, through microbial activity including physical processes, such as volatilization, dilution, sorption, and hydraulic dispersion. (Author)

  13. A study of the acoustical radiation force considering attenuation (United States)

    Wu, RongRong; Liu, XiaoZhou; Gong, XiuFen


    Acoustical tweezer is a primary application of the radiation force of a sound field. When an ultrasound focused beam passes through a micro-particle, like a cell or living biological specimens, the particle will be manipulated accurately without physical contact and invasion, due to the three-dimensional acoustical trapping force. Based on the Ray acoustics approach in the Mie regime, this work discusses the effects on the particle caused by Gaussian focused ultrasound, studies the acoustical trapping force of spherical Mie particles by ultrasound in any position, and analyzes the numerical calculation on the two-dimensional acoustical radiation force. This article also analyzes the conditions for the acoustical trapping phenomenon, and discusses the impact of the initial position and size of the particle on the magnitude of the acoustical radiation force. Furthermore, this paper considers the ultrasonic attenuation in a particle in the case of two-dimension, studies the attenuation's effects on the acoustical trapping force, and amends the calculation to the ordinary case with attenuation.

  14. Adaptive output regulation and circuit realization for a class of attenuated coupled networks (United States)

    Jin, Xiao-Zheng; Park, Ju H.


    In this paper, an adaptive regulation method for couplings and its physical implementation are presented to deal with the problem of output synchronization of networks. The networks are supposed to suffer from a fault described by network attenuation. For the sake of eliminating the adverse impact of network attenuation, a self-regulating network is introduced by adjusting coupling strength based on adaptive technique. By using the Lyapunov stability theory for a synchronization error system, asymptotic output synchronization of the overall networks can be established for the attenuated couplings even without any control input. Moreover, based on the adaptive regulation strategy, an approach for application of knowledge of electricity is proposed to physically realize the self-regulating networks. Finally, numerical simulations on a Rössler oscillator network are given to illustrate the effectiveness of the derived results.

  15. Attenuation of diacylglycerol second messengers

    Energy Technology Data Exchange (ETDEWEB)

    Bishop, W.R.; Ganong, B.R.; Bell, R.M.


    Diacylglycerol(DAG) derived from phosphatidylinositol activates protein kinase C in agonist-stimulated cells. At least two pathways may contribute to the attenuation of the DAG signal: (1) phosphorylation to phosphatidic acid(PA) by DAG kinase(DGK), and (2) deacylation by DAG and monoacylglycerol lipases. A number of DAG analogs were tested as substrates and inhibitors of partially purified pig brain DGK. Two analogs were potent inhibitors in vitro, 1-monooleoylglycerol(MOG,K/sub I/ = 91 and diotanoylethyleneglycol (diC/sub 8/EG, K/sub I/ = 58 These compounds were tested in human platelets. DiC/sub 8/EG inhibited (70 - 100%) (/sup 32/P/sub i/) incorporation into PA in thrombin-stimulated platelets. Under these conditions the DAG signal was somewhat long-lived but was still metabolized, presumably by the lipase pathway. MOG treatment elevated DAG levels up to 4-fold in unstimulated platelets. The DAG formed was in a pool where it did not activate protein kinase C. Thrombin-stimulation of MOG-treated platelets resulted in DAG levels 10-fold higher than control platelets. This appears to be due to the inability of these platelets to metabolize agonist-linked DAG via the lipase pathway. The development of specific inhibitors of DAG kinase and DAG lipase, in conjunction with mass quantification of DAG levels as used here, will provide further insights into the regulation of DAG second messengers.

  16. Live attenuated intranasal influenza vaccine. (United States)

    Esposito, Susanna; Montinaro, Valentina; Groppali, Elena; Tenconi, Rossana; Semino, Margherita; Principi, Nicola


    Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest risk of severe influenza. Live attenuated influenza vaccine (LAIV) has characteristics that can overcome some of these limitations. It does not have to be injected because it is administered intranasally. It is very effective in children and adolescents, among whom it prevents significantly more cases of influenza than the traditional TIV. However, its efficacy in adults has not been adequately documented, which is why it has not been licensed for use by adults by the European health authorities. LAIV is safe and well tolerated by children aged > 2 y and adults, but some concerns arisen regarding its safety in younger children and subjects with previous asthma or with recurrent wheezing. Further studies are needed to solve these problems and to evaluate the possible role of LAIV in the annual vaccination of the general population.

  17. Fitting the full SED of galaxies to put constraints on dust attenuation and star formation determinations (United States)

    Buat, Veronique; Giovannoli, Elodie; Boquien, Mederic; Heinis, Sébastien


    The combination of far-IR and UV-optical rest-frame data has proved to be very efficient to extract physical parameters from the SEDs of galaxies. Using Herschel and ancillary data from the Herschel Reference Survey and GOODS-Herschel Key Projects, we show how dust attenuation properties can be estimated inside local galaxies as well as in the distant Universe.

  18. Graphene-based Electronically Tuneable Microstrip Attenuator

    Directory of Open Access Journals (Sweden)

    L. Pierantoni


    Full Text Available This paper presents the design of a graphene- based electronically tuneable microstrip attenuator operating at a frequency of 5 GHz. The use of graphene as a variable resistor is discussed and the modelling of its electromagnetic properties at microwave frequencies is fully addressed. The design of the graphene-based attenuator is described. The structure integrates a patch of graphene, whose characteristics can range from being a fairly good conductor to a highly lossy material, depending on the applied voltage. By applying the proper voltage through two high-impedance bias lines, the surface resistivity of graphene can be modified, thereby changing the insertion loss of the microstrip attenuator.

  19. Rational Reconstructions of Modern Physics

    CERN Document Server

    Mittelstaedt, Peter


    Newton’s classical physics and its underlying ontology are loaded with several metaphysical hypotheses that cannot be justified by rational reasoning nor by experimental evidence. Furthermore, it is well known that some of these hypotheses are not contained in the great theories of modern physics, such as the theory of relativity and quantum mechanics. This book shows that, on the basis of Newton’s classical physics and by rational reconstruction, the theory of relativity as well as quantum mechanics can be obtained by partly eliminating or attenuating the metaphysical hypotheses. Moreover, it is shown that these reconstructions do not require additional hypotheses or new experimental results.

  20. A linear model approach for ultrasonic inverse problems with attenuation and dispersion. (United States)

    Carcreff, Ewen; Bourguignon, Sébastien; Idier, Jérôme; Simon, Laurent


    Ultrasonic inverse problems such as spike train deconvolution, synthetic aperture focusing, or tomography attempt to reconstruct spatial properties of an object (discontinuities, delaminations, flaws, etc.) from noisy and incomplete measurements. They require an accurate description of the data acquisition process. Dealing with frequency-dependent attenuation and dispersion is therefore crucial because both phenomena modify the wave shape as the travel distance increases. In an inversion context, this paper proposes to exploit a linear model of ultrasonic data taking into account attenuation and dispersion. The propagation distance is discretized to build a finite set of radiation impulse responses. Attenuation is modeled with a frequency power law and then dispersion is computed to yield physically consistent responses. Using experimental data acquired from attenuative materials, this model outperforms the standard attenuation-free model and other models of the literature. Because of model linearity, robust estimation methods can be implemented. When matched filtering is employed for single echo detection, the model that we propose yields precise estimation of the attenuation coefficient and of the sound velocity. A thickness estimation problem is also addressed through spike deconvolution, for which the proposed model also achieves accurate results.

  1. Constraining attenuation uncertainty in common midpoint radar surveys of ice sheets (United States)

    Holschuh, Nicholas; Christianson, Knut; Anandakrishnan, Sridhar; Alley, Richard B.; Jacobel, Robert W.


    For common offset radar data, there is no clear way to disentangle path effects from reflector characteristics, so efforts to determine the physical properties at the bed using reflection amplitude are inherently limited by the constraints on englacial attenuation. In this study, we identify the theoretical considerations required for interpreting bistatic radar surveys and use data collected on the Northeast Greenland Ice Stream and Kamb Ice Stream to compute local attenuation profiles. We found that failing to correct for angle-dependent controls on return power (including antenna directivity, the reflection coefficient, and refractive focusing) can bias the computed attenuation rates as much as 30 dB/km for reflectors at 1 km depth. Because the radiation characteristics are the dominant source of uncertainty in our data, we recommend either a simplified survey design for the future (where the antennae are decoupled from the ice surface) or additional data collection to constrain the near-field permittivity and its effect on the radiation pattern. Depth-averaged attenuation rates computed using common midpoint methods for deep reflectors yield values >10 dB/km higher than attenuation rates computed using common offset techniques with the same data. We attribute these anomalously high attenuation rates to additional wavenumber-dependent (and therefore, angle-dependent) interferences between subwavelength reflectors.

  2. Precision Model for Microwave Rotary Vane Attenuator

    DEFF Research Database (Denmark)

    Guldbrandsen, Tom


    A model for a rotary vane attenuator is developed to describe the attenuator reflection and transmission coefficients in detail. All the parameters of the model can be measured in situ, i.e., without diassembling any part. The tranmission errors caused by internal reflections are calculated from ...... measurements of the much larger reflection parameters, hence commonly used nonprecision instruments can be used to determine the transmission errors with sufficient accuracy for the highest precision obtainable in standard laboratories....

  3. Wave attenuation charcteristics of tethered float system

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.

    and transmitted wave powers, transmission coefficients are computed. The results show that transmission coefficient does not vary with changes in wave height or water depth. When depth of submergence of float increases, wave attenuation decreases, showing... that the system performs well when it is just submerged. As float velocity decreases with increase in float size, transmission coefficient increases with increase in float size. The influence of wave period on wave attenuation is remarkable compared to other...


    DEFF Research Database (Denmark)

    Brunskog, Jonas; Lhomond, Alice; Ohlrich, Mogens


    In this paper the attenuation and flanking transmissions of impact noise in lightweight building structures is studied using a modal approach. The structural field is mainly analysed, putting the main attention to the parts being important in the modelling. The amount of attenuation produced...... by the periodically reinforcing beams used in lightweight building structures is analysed. The consequence of these factors in modelling flanking transmission is also discussed....

  5. Light attenuation in estuarine mangrove lakes (United States)

    Frankovich, Thomas A.; Rudnick, David T.; Fourqurean, James W.


    Submerged aquatic vegetation (SAV) cover has declined in brackish lakes in the southern Everglades characterized by low water transparencies, emphasizing the need to evaluate the suitability of the aquatic medium for SAV growth and to identify the light attenuating components that contribute most to light attenuation. Underwater attenuation of downwards irradiance of photosynthetically active radiation (PAR) was determined over a three year period at 42 sites in shallow (lakes in two sub-estuaries in the coastal Everglades, Florida USA. Turbidity, chromophoric dissolved organic matter (CDOM), and phytoplankton chlorophyll a (chl a) were measured concurrently and their respective contributions to the light attenuation rate were estimated. Light transmission to the benthos relative to literature estimates of minimum requirements for SAV growth indicated that the underwater light environment was often unsuitable for SAV. Light attenuation rates (n = 417) corrected for solar elevation angles ranged from 0.16 m-1 to 9.83 m-1 with a mean of 1.73 m-1. High concentrations of CDOM with high specific light absorption contributed the most to light attenuation followed by turbidity and chl a. CDOM alone sufficiently reduces light transmission beyond the estimated limits for SAV growth, making it difficult for ecosystem managers to increase SAV abundance by management activities. Light limitation of SAV in these areas may be a persistent feature because of their proximity to CDOM source materials from the surrounding mangrove swamp. Increasing freshwater flow into these areas may dilute CDOM concentrations and improve the salinity and light climate for SAV communities.

  6. Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats. (United States)

    Gu, Xiaohuan; Wei, Zheng Zachory; Espinera, Alyssa; Lee, Jin Hwan; Ji, Xiaoya; Wei, Ling; Dix, Thomas A; Yu, Shan Ping


    Neonatal brain trauma is linked to higher risks of mortality and neurological disability. The use of mild to moderate hypothermia has shown promising potential against brain injuries induced by stroke and traumatic brain injury (TBI) in various experimental models and in clinical trials. Conventional methods of physical cooling, however, are difficult to use in acute treatments and in induction of regulated hypothermia. In addition, general anesthesia is usually required to mitigate the negative effects of shivering during physical cooling. Our recent investigations demonstrate the potential therapeutic benefits of pharmacologically induced hypothermia (PIH) using the neurotensin receptor (NTR) agonist HPI201 (formerly known as ABS201) in stroke and TBI models of adult rodents. The present investigation explored the brain protective effects of HPI201 in a P14 rat pediatric model of TBI induced by controlled cortical impact. When administered via intraperitoneal (i.p.) injection, HPI201 induced dose-dependent reduction of body and brain temperature. A 6-h hypothermic treatment, providing an overall 2-3°C reduction of brain and body temperature, showed significant effect of attenuating the contusion volume versus TBI controls. Attenuation occurs whether hypothermia is initiated 15min or 2h after TBI. No shivering response was seen in HPI201-treated animals. HPI201 treatment also reduced TUNEL-positive and TUNEL/NeuN-colabeled cells in the contusion area and peri-injury regions. TBI-induced blood-brain barrier damage was attenuated by HPI201 treatment, evaluated using the Evans Blue assay. HPI201 significantly decreased MMP-9 levels and caspase-3 activation, both of which are pro-apototic, while it increased anti-apoptotic Bcl-2 gene expression in the peri-contusion region. In addition, HPI201 prevented the up-regulation of pro-inflammatory tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and IL-6. In sensorimotor activity assessments, rats in the HPI201

  7. The numerical simulation on electromagnetic wave attenuation characteristics of coal face in time-frequency domain

    Institute of Scientific and Technical Information of China (English)

    YU Shi-jian; Cheng Jiu-long; LIU Jia-qi


    This paper took the abnormal geological objects with high or low resistivity in the coal face as the background to establish the physical model. 2D forward numerical simulation for electromagnetic wave equation was implemented by the finite-difference scheme. According to the simulative results, the attenuation-absorption coefficient were calculated respectively based on field intensity and frequency shift parameter. Research result indicates, when coal-bed contains high electric resistivity geological abnormal object or low electric resistivity geological abnormal object, absorption attenuation function researched by frequency shift parameter of electromagnetic wave signal is more sensitive than by electromagnetic field intensity parameter.

  8. Numerical simulation on propagation and attenuation of shock waves in simplex turn roadway during gas explosion

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Wei; Qu, Zhi-ming; Pian, Long-jiang [University of Science and Technology Beijing, Beijing (China). School of Civil Engineering and Environment


    On the basis of a hypothesis, a physical and mathematical model of the propagation of shock waves in turn roadway was set up. The results of numerical simulation show that the pressure, velocity and temperature of shock wave will be attenuated during propagation. At the beginning of gas explosion, the quantity of parameters of shock wave front is increased gradually because of methane reaction. However, the pressure, velocity and temperature will be attenuated to a small extent after the chemical reaction. By comparison of the experiment, simulation and practice, the highly identical data shows that the numerical model is practicable. 9 refs., 7 figs.

  9. Maximum likelihood estimation of the attenuated ultrasound pulse

    DEFF Research Database (Denmark)

    Rasmussen, Klaus Bolding


    The attenuated ultrasound pulse is divided into two parts: a stationary basic pulse and a nonstationary attenuation pulse. A standard ARMA model is used for the basic pulse, and a nonstandard ARMA model is derived for the attenuation pulse. The maximum likelihood estimator of the attenuated...

  10. Comparison of non-attenuation corrected and attenuation corrected myocardial perfusion SPE

    Directory of Open Access Journals (Sweden)

    Hasan Raza


    Conclusion: This study demonstrates that CT based attenuation corrected Tc-99mm sestamibi SPECT myocardial perfusion imaging significantly improved the specificity of the RCA territory compared with non-attenuation corrected Tc-99mm sestamibi SPECT myocardial perfusion imaging in both genders irrespective of BMI.

  11. Attenuation tomography in West Bohemia/Vogtland (United States)

    Mousavi, Sima; Haberland, Christian; Bauer, Klaus; Hejrani, Babak; Korn, Michael


    We present a three-dimensional (3-D) P-wave attenuation (Qp) model for the geodynamically active swarm earthquake area of West Bohemia/Vogtland in the Czech/German border region. Path-averaged attenuation t* is calculated from amplitude spectra of time windows around the P-wave arrivals of local earthquakes. Average t/t* value or Qp for stations close to Nový Kostel are very low (focal zone (increases up to 500 within 80 km distance). The SIMUL2000 tomography scheme is used to invert the t* for P-wave attenuation perturbation. Analysis of resolution shows that our model is well-resolved in the vicinity of earthquake swarm hypocenters. The prominent features of the model are located around Nový Kostel focal zone and its northern vicinity. Beneath Nový Kostel a vertically stretched (down to depth of 11 km) and a highly attenuating body is observed. We believe that this is due to fracturing and high density of cracks inside the weak earthquake swarm zone in conjunction with presence of free gas/fluid. Further north of Nový Kostel two highly attenuating bodies are imaged which could represent fluid channels toward the surface. The eastern anomaly shows a good correlation with the fluid accumulation area which was suggested in 9HR seismic profile.

  12. Attenuation of Landfill Leachate In Unsaturated Sandstone (United States)

    Butler, A. P.; Brook, C.; Godley, A.; Lewin, K.; Young, C. P.

    Landfill leachate emanating from old "dilute and disperse" sites represents a potential (and in many cases actual) threat to the integrity of groundwater. Indeed, this concern has been included in EU legislation (80/86/EEC), where key contaminants (e.g. ammonia, various toxic organic compounds and heavy metals) are explicitly highlighted in terms of their impact on groundwater. In the UK, whilst there are a substantial number of unlined landfills sited on major aquifers, many of these are in locations where there is a substantial unsaturated zone. Thus, there exists the opportunity for the modification and attenuation of contaminants prior to it encountering the water table. An understanding of likely changes in leachate content and concentrations at such sites will enable a more comprehensive assessment of the potential risks and liabilities posed by such sites to be evaluated. The Burntstump landfill, situated 8 km north of Nottingham (UK), is sited on an outcrop of Sherwood sandstone. The fine friable sand has been quarried since the 1960s and the excavated volume used to store municipal waste. Filling at the site commenced in the mid 1970s and originally was unlined. In 1978 the first of what was to become a series of boreholes was installed within an area of roughly 5 m radius over one of the original waste cells. Cores of the waste and underlying sandstone were extracted and analysed for a range of physical and chemical parameters. The most recent set of analyses were obtained in 2000. The series of investigations therefore provide an important record of leachate migration and modification through the unsaturated zone for over twenty years. The progression of the leachate front is clearly delineated by the chloride concentration profile with an average velocity of around 1.6 m.yr-1. Combining this value with an average (and reasonably uniform) measured moisture content of about 7% gives a mean inter-granular specific discharge of 110 mm.yr-1. An interesting

  13. 3-D seismic velocity and attenuation structures in the geothermal field

    Energy Technology Data Exchange (ETDEWEB)

    Nugraha, Andri Dian [Global Geophysics Research Group, Faculty of Mining and Petroleum Engineering, Institute of Technology Bandung, Jalan Ganesha No. 10 Bandung, 40132 (Indonesia); Syahputra, Ahmad [Geophyisical Engineering, Faculty of Mining and Petroleum Engineering, Institute of Technology Bandung, Jalan Ganesha No. 10 Bandung, 40132 (Indonesia); Fatkhan,; Sule, Rachmat [Applied Geophysics Research Group, Faculty of Mining and Petroleum Engineering, Institute of Technology Bandung, Jalan Ganesha No. 10 Bandung, 40132 (Indonesia)


    We conducted delay time tomography to determine 3-D seismic velocity structures (Vp, Vs, and Vp/Vs ratio) using micro-seismic events in the geothermal field. The P-and S-wave arrival times of these micro-seismic events have been used as input for the tomographic inversion. Our preliminary seismic velocity results show that the subsurface condition of geothermal field can be fairly delineated the characteristic of reservoir. We then extended our understanding of the subsurface physical properties through determining of attenuation structures (Qp, Qs, and Qs/Qp ratio) using micro-seismic waveform. We combined seismic velocities and attenuation structures to get much better interpretation of the reservoir characteristic. Our preliminary attanuation structures results show reservoir characterization can be more clearly by using the 3-D attenuation model of Qp, Qs, and Qs/Qp ratio combined with 3-D seismic velocity model of Vp, Vs, and Vp/Vs ratio.

  14. 3-D seismic velocity and attenuation structures in the geothermal field (United States)

    Nugraha, Andri Dian; Syahputra, Ahmad; Fatkhan, Sule, Rachmat


    We conducted delay time tomography to determine 3-D seismic velocity structures (Vp, Vs, and Vp/Vs ratio) using micro-seismic events in the geothermal field. The P-and S-wave arrival times of these micro-seismic events have been used as input for the tomographic inversion. Our preliminary seismic velocity results show that the subsurface condition of geothermal field can be fairly delineated the characteristic of reservoir. We then extended our understanding of the subsurface physical properties through determining of attenuation structures (Qp, Qs, and Qs/Qp ratio) using micro-seismic waveform. We combined seismic velocities and attenuation structures to get much better interpretation of the reservoir characteristic. Our preliminary attanuation structures results show reservoir characterization can be more clearly by using the 3-D attenuation model of Qp, Qs, and Qs/Qp ratio combined with 3-D seismic velocity model of Vp, Vs, and Vp/Vs ratio.

  15. Monitored Natural Attenuation of ino9rganic Contaminants Treatability Study Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Crapse, K


    The identification and quantification of key natural attenuation processes for inorganic contaminants at D-Area is detailed herein. Two overarching goals of this evaluation of monitored natural attenuation (MNA) as a remediation strategy were (1) to better define the availability of inorganic contaminants as potential sources for transport to groundwater and uptake by environmental receptors and (2) to understand the site-specific mechanisms controlling attenuation of these inorganic contaminants through tandem geochemical and biological characterization. Data collected in this study provides input for more appropriate site groundwater transport models. Significant natural attenuation is occurring at D-Area as evidenced by relatively low aqueous concentrations of constituents of concern (COCs) (Be, Ni, U, and As) at all locations characterized and the decrease in groundwater concentrations with increasing distance from the source. The observed magnitude of decrease in groundwater concentrations of COCs with distance from the D-Area Coal Pile Runoff Basin (DCPRB) could not be accounted for by the modeled physical attenuation processes of dilution/dispersion. This additional attenuation, i.e., the observed difference between the groundwater concentrations of COCs and the modeled physical attenuation, is due to biogeochemical processes occurring at the D-Area. In tandem geochemical and microbiological characterization studies designed to evaluate the mechanisms contributing to natural attenuation, pH was the single parameter found to be most predictive of contaminant attenuation. The increasing pH with distance from the source is likely responsible for increased sorption of COCs to soil surfaces within the aquifer at D-Area. Importantly, because the sediments appear to have a high buffering capacity, the acid emanating from the DCPRB has been neutralized by the soil, and these conditions have led to large Kd values at the site. Two major types of soils are present at

  16. Live attenuated vaccines for invasive Salmonella infections. (United States)

    Tennant, Sharon M; Levine, Myron M


    Salmonella enterica serovar Typhi produces significant morbidity and mortality worldwide despite the fact that there are licensed Salmonella Typhi vaccines available. This is primarily due to the fact that these vaccines are not used in the countries that most need them. There is growing recognition that an effective invasive Salmonella vaccine formulation must also prevent infection due to other Salmonella serovars. We anticipate that a multivalent vaccine that targets the following serovars will be needed to control invasive Salmonella infections worldwide: Salmonella Typhi, Salmonella Paratyphi A, Salmonella Paratyphi B (currently uncommon but may become dominant again), Salmonella Typhimurium, Salmonella Enteritidis and Salmonella Choleraesuis (as well as other Group C Salmonella). Live attenuated vaccines are an attractive vaccine formulation for use in developing as well as developed countries. Here, we describe the methods of attenuation that have been used to date to create live attenuated Salmonella vaccines and provide an update on the progress that has been made on these vaccines.

  17. Research on Nanosecond Pulse Corona Discharge Attenuation

    Institute of Scientific and Technical Information of China (English)

    HE Zheng-hao; XU Huai-li; BAI Jing; YU Fu-sheng; HU Feng; LI Jin


    A line-to-plate reactor was set-up in the experimental study on the application of nanosecond pulsed corona discharge plasma technology in environmental pollution control.Investigation on the attenuation and distortion of the amplitude of the pulse wave front and the discharge image as well as the waveform along the corona wire was conducted.The results show that the wave front decreases sharply during the corona discharge along the corona wire.The higher the amplitude of the applied pulse is,the more the amplitude of the wave front decreased.The wave attenuation responds in a lower corona discharge inversely.To get a higher efficiency of the line-to-plate reactor a sharp attenuation of the corona has to be considered in practical design.

  18. Is there seismic attenuation in the mantle? (United States)

    Ricard, Y.; Durand, S.; Montagner, J.-P.; Chambat, F.


    The small scale heterogeneity of the mantle is mostly due to the mixing of petrological heterogeneities by a smooth but chaotic convection and should consist in a laminated structure (marble cake) with a power spectrum S(k) varying as 1/k, where k is the wavenumber of the anomalies. This distribution of heterogeneities during convective stirring with negligible diffusion, called Batchelor regime is documented by fluid dynamic experiments and corresponds to what can be inferred from geochemistry and seismic tomography. This laminated structure imposes density, seismic velocity and potentially, anisotropic heterogeneities with similar 1/k spectra. A seismic wave of wavenumber k0 crossing such a medium is partly reflected by the heterogeneities and we show that the scattered energy is proportional to k0S(2k0). The reduction of energy for the propagating wave appears therefore equivalent to a quality factor 1/Q∝k0S(2k0). With the specific 1/k spectrum of the mantle, the resulting apparent attenuation should therefore be frequency independent. We show that the total contribution of 6-9% RMS density, velocity and anisotropy would explain the observed S and P attenuation of the mantle. Although these values are large, they are not unreasonable and we discuss how they depend on the range of frequencies over which the attenuation is explained. If such a level of heterogeneity were present, most of the attenuation of the Earth would be due to small scale scattering by laminations, not by intrinsic dissipation. Intrinsic dissipation must certainly exist but might correspond to a larger, yet unobserved Q. This provocative result would explain the very weak frequency dependence of the attenuation, and the fact that bulk attenuation seems negligible, two observations that have been difficult to explain for 50 years.

  19. An indirect method of X-ray spectra measurement by simultaneous attenuations of the scattered beam

    Energy Technology Data Exchange (ETDEWEB)

    Mainardi, Raul T. [Facultad de Matematica, Astronomia y Fisica (FaMAF), Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA-Cordoba (Argentina)], E-mail:; Bonzi, Edgardo V. [Facultad de Matematica, Astronomia y Fisica (FaMAF), Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA-Cordoba (Argentina)


    Direct and indirect methods of X-ray spectra determination present obstacles to their practical use since they must position either the collimator-detector assembly or the attenuators-ionization chamber, respectively, along the X-ray beam direction. These arrangements require considerable space and in many instances the detectors promptly saturate. An indirect procedure, which overcomes the aforementioned problems, is developed. It consists of the scattering of the X-ray beam from a carbon disk, which is detected simultaneously by several detectors placed away from the beam. The X-ray flux reaching each of these detectors is attenuated in metal sheets of different thicknesses, thus obtaining simultaneously the attenuation curve values. A set of analytical equations are derived to calculate attenuation curves by taking into account all the absorption and elastic and inelastic scattering processes that a beam of photons undergoes when going from the X-ray tube to the detector. Users, even those who are not well acquainted with computer programming, can easily obtain the X-ray spectrum by a least square fitting of a measured attenuation curve to a previously derived analytical expression. A simulated Monte Carlo program of photon transport from the X-ray tube to the detector provided simulated attenuation curves data. Analytically calculated and simulated attenuation curves for the same input spectrum wholly overlap and furthermore, reconstructed spectra from both sets of curves for different kilovoltages are also in full agreement. Finally, in addition to the importance of having the detectors out of the beam direction, the proposed arrangement features other main advantages, namely, only one X-ray tube shot is needed to obtain the required data, the physical processes involved are very well known, analytical equations are easily interpreted, and the measuring apparatuses can be comparatively simple to assemble and operate.

  20. Pulse wave attenuation measurement by linear and nonlinear methods in nonlinearly elastic tubes. (United States)

    Bertram, C D; Pythoud, F; Stergiopulos, N; Meister, J J


    Reasons for the continuing difficulty in making definitive measurements of pulse wave attenuation in elastic tubes and arteries in the presence of reflections are sought. The measurement techniques available were re-examined in elastic tubes mimicking the arterial compliance nonlinearity, under conditions of strong reflection. The pulse was of physiological shape, and two different pulse amplitudes in the physiological range were used. Measurements of pressure, flow-rate and diameter pulsation allowed the deployment of four of the classical linear methods of analysis. In addition, a method of separating the forward- and backward-travelling waves that does not require linearising assumptions was used, and the attenuation in the forward and reverse directions was calculated from the resulting waveforms. Overall, the results obtained here suggest that a fully satisfactory way of measuring arterial attenuation has yet to be devised. The classical linear methods all provided comparable attenuation estimates in terms of average value and degree of scatter across frequency. Increased scatter was generally found at the higher pulse amplitude. When the forward waveforms from the separation were similarly compared in terms of frequency components, the average value at energetic harmonics was similar to both the value indicated by the linear methods and the values predicted from linear theory on the basis of estimated viscous and viscoelastic parameter data. The backward waveforms indicated a physically unreasonable result, attributed as the expression for this technique of the same difficulties that normally manifest in scatter. Data in the literature suggesting that one of the classical methods, the three-point, systematically over-estimates attenuation were not supported, but it was confirmed that this method becomes prone to negative attenuation estimates at low harmonics as pulse amplitude increases. Although the goal of definitive attenuation measurement remains elusive

  1. Phase Velocity and Attenuation of Longitudinal Shear Vibrations of Hollow Poroelastic Cylinders

    Directory of Open Access Journals (Sweden)

    Ahmed Shah S.


    Full Text Available The present paper is devoted to the study of phase velocity and attenuation of longitudinal shear vibrations of hollow poroelastic circular cylinders in the presence of dissipation. The explicit expressions for phase velocity and attenuation of longitudinal shear vibrations are derived. The frequency equation of longitudinal shear vibrations and modes obtained in a previous paper are used to compute the phase velocity and attenuation for different dissipations for thin and thick poroelastic cylindrical shells and poroelastic solid cylinder. The physical parameters of sandstone saturated with kerosene and sandstone saturated with water are used for the purpose of computation. It is found that the phase velocity is linear beyond certain frequency. Phase velocity is smaller for a typical anti-symmetric mode compared to the flexural mode. It is greater for the second mode than that of the first mode. Also the phase velocity is larger for a thin poroelastic cylindrical shell than that of a thick poroelastic cylindrical shell. The same is true for attenuation also. Attenuation is very high for the considered dissipations and it increases with the increase in dissipation.

  2. Simulating Atmospheric Free-Space Optical Propagation; Part II: Haze, Fog, and Low Clouds Attenuations (United States)

    Achour, Maha


    One of the biggest challenges facing Free-Space Optics deployment is proper understanding of optical signal propagation in different atmospheric conditions. In an earlier study by the author (30), attenuation by rain was analyzed and successfully modeled for infrared signal transmission. In this paper, we focus on attenuation due to scattering by haze, fog and low clouds droplets using the original Mie Scattering theory. Relying on published experimental results on infrared propagation, electromagnetic waves scattering by spherical droplet, atmospheric physics and thermodynamics, UlmTech developed a computer-based platform, Simulight, which simulates infrared signal (750 nm-12 μm) propagation in haze, fog, low clouds, rain and clear weather. Optical signals are scattered by fog droplets during transmission in the forward direction preventing the receiver from detecting the minimum required power. Weather databases describe foggy conditions by measuring the visibility parameter, which is, in general, defined as the maximum distance that the visible 550 nm signal can travel while distinguishing between the target object and its background at 2% contrast. Extrapolating optical signal attenuations beyond 550 nm using only visibility is not as straightforward as stated by the Kruse equation which is unfortunately widely used. We conclude that it is essential to understand atmospheric droplet sizes and their distributions based on measured attenuations to effectively estimate infrared attenuation. We focus on three types of popular fogs: Evolving, Stable and Selective.

  3. Ultrasound transmission attenuation tomography using energy-scaled amplitude ratios (United States)

    Chen, Ting; Shin, Junseob; Huang, Lianjie


    Ultrasound attenuation of breast tumors is related to their types and pathological states, and can be used to detect and characterize breast cancer. Particularly, ultrasound scattering attenuation can infer the margin properties of breast tumors. Ultrasound attenuation tomography quantitatively reconstructs the attenuation properties of the breast. Our synthetic-aperture breast ultrasound tomography system with two parallel transducer arrays records both ultrasound reflection and transmission signals. We develop an ultrasound attenuation tomography method using ultrasound energy-scaled amplitude decays of ultrasound transmission signals and conduct ultrasound attenuation tomography using a known sound-speed model. We apply our ultrasound transmission attenuation tomography method to a breast phantom dataset, and compare the ultrasound attenuation tomography results with conventional beamforming ultrasound images obtained using reflection signals. We show that ultrasound transmission attenuation tomography complements beamforming images in identifying breast lesions.

  4. Touch Attenuates Infants' Physiological Reactivity to Stress (United States)

    Feldman, Ruth; Singer, Magi; Zagoory, Orna


    Animal studies demonstrate that maternal touch and contact regulate infant stress, and handling during periods of maternal deprivation attenuates the stress response. To measure the effects of touch on infant stress reactivity during simulated maternal deprivation, 53 dyads were tested in two paradigms: still-face (SF) and still-face with maternal…

  5. Microwave attenuation with composite of copper microwires

    Energy Technology Data Exchange (ETDEWEB)

    Gorriti, A.G.; Marin, P. [Instituto de Magnetismo Aplicado, (UCM-ADIF-CSIC) and Departamento de Fisica de Materiales (UCM). P.O. Box 155, Las Rozas, Madrid 28230 (Spain); Cortina, D. [Micromag S.L., Las Rozas, Madrid 28230 (Spain); Hernando, A., E-mail: antonio.hernando@adif.e [Instituto de Magnetismo Aplicado, (UCM-ADIF-CSIC) and Departamento de Fisica de Materiales (UCM). P.O. Box 155, Las Rozas, Madrid 28230 (Spain); Micromag S.L., Las Rozas, Madrid 28230 (Spain)


    It is shown that copper microwires composite media attenuates microwave reflection of metallic surfaces. We show how the distance to the metallic surface, as well as the length and volume fraction of microwires, determine the frequency of maximum absorption and the return loss level. Furthermore, we were able to fit the experimental results with a theoretical model based on Maxwell-Garnett mixing formula.

  6. GPR measurements of attenuation in concrete

    Energy Technology Data Exchange (ETDEWEB)

    Eisenmann, David, E-mail:; Margetan, Frank J., E-mail:; Pavel, Brittney, E-mail: [Center for Nondestructive Evaluation, Iowa State University, 1915 Scholl Road, Ames, IA 50011-3042 (United States)


    Ground-penetrating radar (GPR) signals from concrete structures are affected by several phenomenon, including: (1) transmission and reflection coefficients at interfaces; (2) the radiation patterns of the antenna(s) being used; and (3) the material properties of concrete and any embedded objects. In this paper we investigate different schemes for determining the electromagnetic (EM) attenuation of concrete from measured signals obtained using commercially-available GPR equipment. We adapt procedures commonly used in ultrasonic inspections where one compares the relative strengths of two or more signals having different travel paths through the material of interest. After correcting for beam spread (i.e., diffraction), interface phenomena, and equipment amplification settings, any remaining signal differences are assumed to be due to attenuation thus allowing the attenuation coefficient (say, in dB of loss per inch of travel) to be estimated. We begin with a brief overview of our approach, and then discuss how diffraction corrections were determined for our two 1.6 GHz GPR antennas. We then present results of attenuation measurements for two types of concrete using both pulse/echo and pitch/catch measurement setups.

  7. Sizes of mantle heteogeneities and seismic attenuation (United States)

    Ricard, Y. R.; durand, S.; Chambat, F.; Montagner, J.


    The small scale heterogeneity of the mantle, being mostly due to the mixing of petrological heterogeneities by a smooth but chaotic convection should consist in a laminated structure (marble cake) with a power spectrum S(k) varying as 1/k, where k is the wavenumber of the anomalies. This distribution of heterogeneities during convective stirring with negligible diffusion, called Batchelor regime is documented by fluid dynamic experiments and corresponds to what can be inferred from geochemistry and seismic tomography. This laminated structure imposes density, seismic velocity and potentially, anisotropic heterogeneities with similar 1/k spectrums. We show that a seismic wave of wavenumber k_0 crossing such medium is partly reflected by the heterogeneities and the scattered energy has an energy found proportional to k_0 S(2k_0). The reduction of energy for the propagating wave appears therefore equivalent to a quality factor 1/Q proportional to k_0 S(2k_0). With the specific 1/k spectrum of the mantle, the resulting apparent attenuation should therefore be frequency independent. We show that the total contribution of 6-9% RMS density, velocity and anisotropy would explain the observed S and P attenuation of the mantle. Although these values are large there are not unreasonable and we discuss how they are likely overestimated. In this case, most of the attenuation of the Earth would be due to small scale scattering by laminations not by intrinsic dissipation. Intrinsic dissipation must certainly exists but might correspond to a larger, yet unobserved Q. This provocative result would explain the observed very weak frequency dependence of the attenuation, and the fact that bulk attenuation seems negligeable, two observations that have been difficult to explain for 50 years.

  8. Particle physics

    CERN Document Server

    Martin, Brian R


    An accessible and carefully structured introduction to Particle Physics, including important coverage of the Higgs Boson and recent progress in neutrino physics. Fourth edition of this successful title in the Manchester Physics series. Includes information on recent key discoveries including : An account of the discovery of exotic hadrons, beyond the simple quark model; Expanded treatments of neutrino physics and CP violation in B-decays; An updated account of ‘physics beyond the standard model’, including the interaction of particle physics with cosmology; Additional problems in all chapters, with solutions to selected problems available on the book’s website; Advanced material appears in optional starred sections.

  9. Statistical Physics

    CERN Document Server

    Mandl, Franz


    The Manchester Physics Series General Editors: D. J. Sandiford; F. Mandl; A. C. Phillips Department of Physics and Astronomy, University of Manchester Properties of Matter B. H. Flowers and E. Mendoza Optics Second Edition F. G. Smith and J. H. Thomson Statistical Physics Second Edition E. Mandl Electromagnetism Second Edition I. S. Grant and W. R. Phillips Statistics R. J. Barlow Solid State Physics Second Edition J. R. Hook and H. E. Hall Quantum Mechanics F. Mandl Particle Physics Second Edition B. R. Martin and G. Shaw The Physics of Stars Second Edition A. C. Phillips Computing for Scient

  10. Probiotic Cheese Attenuates Exercise-induced Immune Suppression In Wistar Rats


    Lollo P.C.B.; Cruz A.G.; Morato P.N.; Moura C.S.; Carvalho-Silva L.B.; Oliveira C.A.F.; Faria J.A.F.; Amaya-Farfan J.


    Intense physical activity results in a substantial volume of stress and hence a significant probability of immunosuppression in athletes, with milk proteins being, perhaps, the most recommended protein supplements. Consumption of a probiotic cheese can attenuate immune suppression induced by exhausting exercise in rats. A popular Brazilian fresh cheese (Minas Frescal cheese) containing Lactobacillus acidophilus LA14 and Bifidobacterium longum BL05 was fed for 2 wk to adult Wistar rats, which ...

  11. Attenuation of seismic waves in Central Egypt

    Directory of Open Access Journals (Sweden)

    Mamdouh Abbas Morsy


    Full Text Available Attenuation of seismic waves in central Egypt had never been studied before. The results of the research on the seismic attenuation are based upon the information collected by the seismological network from 1998 to 2011. 855 earthquakes were selected from the Egyptian seismological catalog, with their epicenter distances between 15 and 150 km, their magnitudes ranging from 2 and 4.1 and focal depths reaching up to 30 km. The first systematic study of attenuation derived from the P-, S- and coda wave in the frequency range 1–24 Hz is presented. In the interpretation of the results both single and multiple scattering in a half space are considered. The single scattering model proposed by Sato (1977 was used. Two methods, the coda (Qc and the Multiple Lapse Time Window (MLTW method are used. The aim of this study is to validate these interpretations in the region and to try to identify the effects of attenuation due to intrinsic (Qi and scattering attenuation (Qsc. The mean Qc value calculated was Qc = (39 ± 1f1.0±0.009. The average Qc at 1.5 Hz is (53 ± 6 and Qc = (900 ± 195 at 24 Hz with Qo ranging between 23 and 107, where η ranging between 0.9 and 1.3. The quality factor (Q was estimated from spectra of P- and S-waves by applying a spectral ratio technique. The results show variations in Qp and QS as a function of frequency, according to the power law Q = 56η1.1. The seismic albedo is 0.7 at all stations and it mean that the earthquake activity is due to tectonic origin. The attenuation and frequency dependency for different paths and the correlation of the results with the geotectonic of the region are presented. The Qc values were calculated and correlated with the geology and tectonics of the area. The relatively low Qo and the high frequency dependency agree with the values of a region characterized by a low tectonic activity and vise versa.

  12. Physical activity (United States)

    ... this page: // Physical activity To use the sharing features on this page, please enable JavaScript. Physical activity -- which includes an active lifestyle and routine exercise -- ...

  13. Recommendations for processing atmospheric attenuated backscatter profiles from Vaisala CL31 ceilometers (United States)

    Kotthaus, Simone; O'Connor, Ewan; Münkel, Christoph; Charlton-Perez, Cristina; Haeffelin, Martial; Gabey, Andrew M.; Grimmond, C. Sue B.


    Ceilometer lidars are used for cloud base height detection, to probe aerosol layers in the atmosphere (e.g. detection of elevated layers of Saharan dust or volcanic ash), and to examine boundary layer dynamics. Sensor optics and acquisition algorithms can strongly influence the observed attenuated backscatter profiles; therefore, physical interpretation of the profiles requires careful application of corrections. This study addresses the widely deployed Vaisala CL31 ceilometer. Attenuated backscatter profiles are studied to evaluate the impact of both the hardware generation and firmware version. In response to this work and discussion within the CL31/TOPROF user community (TOPROF, European COST Action aiming to harmonise ground-based remote sensing networks across Europe), Vaisala released new firmware (versions 1.72 and 2.03) for the CL31 sensors. These firmware versions are tested against previous versions, showing that several artificial features introduced by the data processing have been removed. Hence, it is recommended to use this recent firmware for analysing attenuated backscatter profiles. To allow for consistent processing of historic data, correction procedures have been developed that account for artefacts detected in data collected with older firmware. Furthermore, a procedure is proposed to determine and account for the instrument-related background signal from electronic and optical components. This is necessary for using attenuated backscatter observations from any CL31 ceilometer. Recommendations are made for the processing of attenuated backscatter observed with Vaisala CL31 sensors, including the estimation of noise which is not provided in the standard CL31 output. After taking these aspects into account, attenuated backscatter profiles from Vaisala CL31 ceilometers are considered capable of providing valuable information for a range of applications including atmospheric boundary layer studies, detection of elevated aerosol layers, and model

  14. Frequency Dependence of Attenuation Constant of Dielectric Materials

    Directory of Open Access Journals (Sweden)

    A. S. Zadgaonkar


    Full Text Available Different dielectric materials have been studied for frequency dependence of attenuation constant. The sensitive cathode ray oscillograph method has been used to evaluate to the dielectric constant and loss factor, and from these attenuation constants have been calculated. The temperature remaining constant, a regular increase has been observed in attenuation constant, at higher frequencies of electro-magnetic propagating wave.

  15. On the excess attenuation of sound in the atmosphere (United States)

    Deloach, R.


    The attenuation suffered by an acoustic plane wave propagating from an elevated source to the ground, in excess of absorption losses, was studied. Reported discrepancies between attenuation measurements made in the field and theories which only account for absorption losses are discussed. It was concluded that the scattering of sound by turbulence results in a nonnegligible contribution to the total attenuation.

  16. Attenuation of microwaves by poly-disperse small spheroid particles (United States)

    Zhang, Peichang; Wang, Zhenhui


    Expressions for calculating the attenuation cross sections of poly-disperse, small spheroids, whose rotatory axes are in specific status, have been derived from a universal formula for calculating the attenuation cross section of a particle of arbitrary shape. Attenuation cross sections of liquid, ice, and spongy spheroidal droplets in different size and eccentricity at different wave lengths have been computed and analyzed.

  17. P- and S-wave seismic attenuation for deep natural gas exploration and development

    Energy Technology Data Exchange (ETDEWEB)

    Walls, Joel [Rock Solid Images, Houston, TX (United States); Uden, Richard [Rock Solid Images, Houston, TX (United States); Singleton, Scott [Rock Solid Images, Houston, TX (United States); Shu, Rone [Rock Solid Images, Houston, TX (United States); Mavko, Gary [Stanford Univ., CA (United States)


    Using current methods, oil and gas in the subsurface cannot be reliably predicted from seismic data. This causes domestic oil and gas fields to go undiscovered and unexploited, thereby increasing the need to import energy.The general objective of this study was to demonstrate a simple and effective methodology for estimating reservoir properties (gas saturation in particular, but also including lithology, net to gross ratios, and porosity) from seismic attenuation and other attributes using P- and S-waves. Phase I specific technical objectives: Develop Empirical or Theoretical Rock Physics Relations for Qp and Qs; Create P-wave and S-wave Synthetic Seismic Modeling Algorithms with Q; and, Compute P-wave and S-wave Q Attributes from Multi-component Seismic Data. All objectives defined in the Phase I proposal were accomplished. During the course of this project, a new class of seismic analysis was developed based on compressional and shear wave inelastic rock properties (attenuation). This method provides a better link between seismic data and the presence of hydrocarbons. The technique employs both P and S-wave data to better discriminate between attenuation due to hydrocarbons versus energy loss due to other factors such as scattering and geometric spreading. It was demonstrated that P and S attenuation can be computed from well log data and used to generate synthetic seismograms. Rock physics models for P and S attenuation were tested on a well from the Gulf of Mexico. The P- and S-wave Q attributes were computed on multi-component 2D seismic data intersecting this well. These methods generated reasonable results, and most importantly, the Q attributes indicated gas saturation.

  18. Attenuation tomography in the rupture area of the 2010 M8.8 Maule, Chile, earthquake (United States)

    Heather-Smith, Helen; Rietbrock, Andreas


    In recent years several seismological studies have developed a detailed image of the megathrust interface between the subducting Nazca plate and and the overriding South American plate in the rupture area of the 2010 M8.8 Maule, Chile, earthquake. Hicks et al. (2014) have published a high resolution 3D seismic tomography model and characterised the different regimes acting along the interface based on their seismic properties. A more detailed study by Moreno et al. (2014) showed that the seismic Vp/Vs ratio and inter-seismic locking determined from GPS measurements are correlated. Together these observations open up the possibility to map the rupture potential of possible future earthquakes, although the underlying processes are yet not fully understood and a more in depth analysis of other physical properties is needed. 3D seismic attenuation structure as well as seismic stress-drop distribution based on the aftershock seismicity are providing independent data sets to better constrain the physical processes acting along the subduction zone interface. As seismic attenuation is particularly sensitive to fluid saturation it opens up the possibility to study more directly the influence of fluids on aftershock activity as compared to standard velocity tomography studies. Based on our event catalogue of approximately 30,000 aftershocks we are currently selecting the most appropriate data set for the staggered 3D attenuation tomography. The inverted attenuation model will then be used to calculate seismic stress drop values for the complete aftershock catalogue. We will present our preliminary 3D attenuation model together with our stress drop estimates and compare our finding to the 3D velocity structure and slip distribution.

  19. Attenuated partial internal reflection infrared spectroscopy. (United States)

    Zhang, Zhenfeng; Ewing, George E


    A new method for the spectroscopic study of absorbing films is proposed. In contrast to the well-established methods that take advantage of the attenuation of total internal reflection (ATR) to obtain spectra, we intentionally arrange the optics to permit partial internal reflection from the sampling prism face. Attenuated partial internal reflection (APR) spectroscopy is introduced through theoretical calculations and experimental demonstrations. The calculated APR spectra in the infrared region were generated from the Fresnel and Airy equations. Experimentally, APR spectra of water films on a NaCl prism were obtained. APR is more sensitive than ATR, and can easily distinguish water films at the monolayer level (310 pm). The determination of film thickness from interference fringes in APR spectra is also illustrated. It is shown that APR can be used for film thickness measurements that can span 6 orders of magnitude. The limitations of APR are also discussed.

  20. Particle size characterization by ultrasonic attenuation spectra

    Institute of Scientific and Technical Information of China (English)

    Mingxu Su; Minghua Xue; Xiaoshu Cai; Zhitao Shang; Feng Xu


    This paper contributes to extracting information from signals of broadband ultrasonic attenuation spectrum for effective utilization in particle size characterization. The single particle scattering model and the coupled-phase model are formulated simultaneously, the relationship between particle size distribution and ultrasonic spectrum is established, and a convergence criterion for calculation is quantified. Demonsa'ation inversion by the optimum regularization factor method is carded out to yield typical numerical results for discussion. With the experimental set-up developed by the Institute of Particle and Two-Phase Flow Measurement (IPTFM) at the University of Shanghai for Science and Technology, sand sediment particle size is measured by attenuation spectrum and analyzed using the above inversion algorithm and theoretical models. To validate the proposed ultrasonic spectrum particle sizing method, results are compared with those obtained by microscopy.

  1. Attenuated psychosis syndrome: benefits of explicit recognition (United States)

    SCHIFFMAN, Jason; CARPENTER, William T


    Summary Given the unique characteristics of people who meet criteria for attenuated psychosis syndrome (APS) and the growing literature on the clinical benefits of providing services to individuals who meet these criteria, the APS diagnosis serves an important, and previously missing, role in psychiatry. The promotion of the APS diagnosis should help reduce the over-diagnosis and over-treatment of individuals with prodromal psychotic conditions and it should also encourage expanded training about attenuated psychosis among clinicians who primarily provide services to youth (a primary group who are diagnosed with APS). Only some of the individuals with APS subsequently develop psychosis, but all have existing clinical needs – regardless of subsequent conversion. The formal recognition of APS in DSM-5 will facilitate the research needed to identify and meet those needs. PMID:25852257

  2. Carcinoma cervix with fat attenuating skull metastases

    Institute of Scientific and Technical Information of China (English)

    Anuradha Kapali; Atmakuri Sateesh Kumar; Mukunda Malathi; S D Shamsundar


    Skeletal metastasis in carcinoma cervix occurs in about 0.8-23% of cases. These lesions are usually radiographically lytic. Very few cases of metastases to the skull have been identiifed, about 5 cases to the best of our knowledge. We present a case of adenosquamous cell carcinoma of cervix with fat attenuating skull metastases in a 38-year-old lady that is not reported till date. The lesion was lytic, expansile and with negative attenuation of -15 to -30 Hounsifeld units corresponding to fat.Metastases must be included in the differentials of scalp lesions. A history of recent onset of swelling and associated lytic areas in calvarium on contrast enhanced computed tomography with multiplicity can give a clue to metastatic nature of disease.

  3. Physical ergonomics

    NARCIS (Netherlands)

    Looze, M. de; Koningsveld, E.


    Physical ergonomics deals with the physical load on the human body when performing activities like work, sports, jobs at home or dealing with products. With regard to the exposure to physical loads and its potential effects on the human body, the presented framework is helpful. In this article we ex

  4. LCLS XTOD Attenuator System System Concept Report

    Energy Technology Data Exchange (ETDEWEB)

    Kishiyama, K; Roeben, M; Trent, J; Ryutov, D; Shen, S


    The attenuator system for the Linac Coherent Light Source (LCLS) X-ray Transport, Optics and Diagnostics (XTOD) system has been configured and analyzed by the Lawrence Livermore National Laboratory's New Technologies Engineering Division (NTED) as requested by the SLAC/LCLS program. The system layout, performance analyses and selection of the vacuum components are presented in this System Conceptual Review (SCR) report. Also included are the plans for prototype, procurement, mechanical integration, and the cost estimates.

  5. Narrow terahertz attenuation signatures in Bacillus thuringiensis. (United States)

    Zhang, Weidong; Brown, Elliott R; Viveros, Leamon; Burris, Kellie P; Stewart, C Neal


    Terahertz absorption signatures from culture-cultivated Bacillus thuringiensis were measured with a THz photomixing spectrometer operating from 400 to 1200 GHz. We observe two distinct signatures centered at ∼955 and 1015 GHz, and attribute them to the optically coupled particle vibrational resonance (surface phonon-polariton) of Bacillus spores. This demonstrates the potential of the THz attenuation signatures as "fingerprints" for label-free biomolecular detection.

  6. Molecular Characterization of Attenuated Junin Virus Variants. (United States)


    No. DAMD17-89-Z-9024 Area de Quimica Biologica y Biologia Molecular Facultad de Ciencias Exactas Universidad Nacional de La Plata Calles 47 y 115, 1900...MONITORING ORGANIZATION Area de Quimica Biologica (If applicable) y Biologia Molecular I 6c. ADDRESS (City, State, and ZIPCode) 7b. ADDRESS (City, State...AD-A260 128 AD____ MOLECULAR CHARACTERIZATION OF ATTENUATED JUNIN VIRUS VARIANTS FINAL REPORT VICTOR ROMANOWSKI PABLO D. GHIRINGHELLI CESAR G

  7. Novel Intriguing Strategies Attenuating to Sarcopenia

    Directory of Open Access Journals (Sweden)

    Kunihiro Sakuma


    Full Text Available Sarcopenia, the age-related loss of skeletal muscle mass, is characterized by a deterioration of muscle quantity and quality leading to a gradual slowing of movement, a decline in strength and power, increased risk of fall-related injury, and, often, frailty. Since sarcopenia is largely attributed to various molecular mediators affecting fiber size, mitochondrial homeostasis, and apoptosis, the mechanisms responsible for these deleterious changes present numerous therapeutic targets for drug discovery. Resistance training combined with amino acid-containing supplements is often utilized to prevent age-related muscle wasting and weakness. In this review, we summarize more recent therapeutic strategies (myostatin or proteasome inhibition, supplementation with eicosapentaenoic acid (EPA or ursolic acid, etc. for counteracting sarcopenia. Myostatin inhibitor is the most advanced research with a Phase I/II trial in muscular dystrophy but does not try the possibility for attenuating sarcopenia. EPA and ursolic acid seem to be effective as therapeutic agents, because they attenuate the degenerative symptoms of muscular dystrophy and cachexic muscle. The activation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α in skeletal muscle by exercise and/or unknown supplementation would be an intriguing approach to attenuating sarcopenia. In contrast, muscle loss with age may not be influenced positively by treatment with a proteasome inhibitor or antioxidant.

  8. Introduction to radiological physics and radiation dosimetry

    CERN Document Server

    Attix, Frank Herbert


    A straightforward presentation of the broad concepts underlying radiological physics and radiation dosimetry for the graduate-level student. Covers photon and neutron attenuation, radiation and charged particle equilibrium, interactions of photons and charged particles with matter, radiotherapy dosimetry, as well as photographic, calorimetric, chemical, and thermoluminescence dosimetry. Includes many new derivations, such as Kramers X-ray spectrum, as well as topics that have not been thoroughly analyzed in other texts, such as broad-beam attenuation and geometrics, and the reciprocity theorem

  9. Particle Physics

    CERN Document Server

    Martin, B R


    An essential introduction to particle physics, with coverage ranging from the basics through to the very latest developments, in an accessible and carefully structured text. Particle Physics: Third Edition is a revision of a highly regarded introduction to particle physics. In its two previous editions this book has proved to be an accessible and balanced introduction to modern particle physics, suitable for those students needed a more comprehensive introduction to the subject than provided by the 'compendium' style physics books. In the Third Edition the standard mod

  10. Physical Systems

    CERN Document Server

    Belkind, Ori


    Based on the concept of a physical system, this book offers a new philosophical interpretation of classical mechanics and the Special Theory of Relativity. According to Belkind's view the role of physical theory is to describe the motions of the parts of a physical system in relation to the motions of the whole. This approach provides a new perspective into the foundations of physical theory, where motions of parts and wholes of physical systems are taken to be fundamental, prior to spacetime, material properties and laws of motion. He defends this claim with a constructive project, deriving b

  11. Understanding physics

    CERN Document Server

    Mansfield, Michael


    Understanding Physics - Second edition is a comprehensive, yet compact, introductory physics textbook aimed at physics undergraduates and also at engineers and other scientists taking a general physics course. Written with today's students in mind, this text covers the core material required by an introductory course in a clear and refreshing way. A second colour is used throughout to enhance learning and understanding. Each topic is introduced from first principles so that the text is suitable for students without a prior background in physics. At the same time the book is designed to enable

  12. Cosmoparticle physics

    CERN Document Server

    Khlopov, M Yu


    Since the 1980s the cross-disciplinary, multidimensional field of links between cosmology and particle physics has been widely recognised by theorists, studying cosmology, particle and nuclear physics, gravity, as well as by astrophysicists, astronomers, space physicists, experimental particle and nuclear physicists, mathematicians and engineers.The relationship between cosmology and particle physics is now one of the important topics of discussion at any scientific meeting both on astrophysics and high energy physics.Cosmoparticle physics is the result of the mutual relationship between cosmo

  13. Game physics

    CERN Document Server

    Eberly, David H


    ""Game Physics, 2nd Edition"" provides clear descriptions of the mathematics and algorithms needed to create a powerful physics engine - while providing a solid reference for all of the math you will encounter anywhere in game development: quaternions, linear algebra, and calculus. Implementing physical simulations for real-time games is a complex task that requires a solid understanding of a wide range of concepts from the fields of mathematics and physics. Previously, the relevant information could only be gleaned through obscure research papers. Thanks to ""Game Physics"", all this informa

  14. Seismic Attenuation Inversion with t* Using tstarTomog.

    Energy Technology Data Exchange (ETDEWEB)

    Preston, Leiph


    Seismic attenuation is defined as the loss of the seismic wave amplitude as the wave propagates excluding losses strictly due to geometric spreading. Information gleaned from seismic waves can be utilized to solve for the attenuation properties of the earth. One method of solving for earth attenuation properties is called t*. This report will start by introducing the basic theory behind t* and delve into inverse theory as it pertains to how the algorithm called tstarTomog inverts for attenuation properties using t* observations. This report also describes how to use the tstarTomog package to go from observed data to a 3-D model of attenuation structure in the earth.

  15. Rational reconstructions of modern physics

    CERN Document Server

    Mittelstaedt, Peter


    Newton’s classical physics and its underlying ontology are loaded with several metaphysical hypotheses that cannot be justified by rational reasoning nor by experimental evidence. Furthermore, it is well known that some of these hypotheses are not contained in the great theories of Modern Physics, such as the theory of Special Relativity and Quantum Mechanics. This book shows that, on the basis of Newton’s classical physics and by rational reconstruction, the theory of Special Relativity as well as Quantum Mechanics can be obtained by partly eliminating or attenuating the metaphysical hypotheses. Moreover, it is shown that these reconstructions do not require additional hypotheses or new experimental results. In the second edition the rational reconstructions are completed with respect to General Relativity and Cosmology. In addition, the statistics of quantum objects is elaborated in more detail with respect to the rational reconstruction of quantum mechanics. The new material completes the approach of t...

  16. Are the costs of neuroticism inevitable? Evidence of attenuated effects in U.S. Latinas. (United States)

    Campos, Belinda; Busse, David; Yim, Ilona S; Dayan, Adam; Chevez, Linett; Schoebi, Dominik


    Neuroticism is the heritable and stable personality trait defined by the tendency to experience negative emotion, be easily stressed, and slow to soothe. Neuroticism poses a risk for poor social and health outcomes that has been identified as a major public health concern. To date, factors that attenuate neuroticism's costs have not been identified. The goal of this work was to test the hypothesis that the costs of neuroticism would be attenuated in sociocultural contexts that emphasize readily accessible social support, emotional positivity, and physical proximity in interdependent relationships. U.S. Latino culture fits these characteristics. Two studies, an online survey study (Study 1) and a laboratory study (Study 2), tested whether three key costs of high neuroticism-less support (Study 1), more distress (Study 2), and blunted cortisol reactivity (Study 2)-would be attenuated in U.S. Latinas relative to non-Latinas of European and East Asian cultural background. Consistent with previous research, neuroticism was associated with less perceived support, more distress, and blunted cortisol reactivity in non-Latina women of European and East Asian cultural background. For Latina women, however, these effects were attenuated. Latina women who were high in neuroticism continued to feel supported, were not as distressed, and their cortisol reactivity was less blunted. The role of sociocultural context for generating a better understanding of personality processes and the social malleability of neuroticism's costs are discussed.


    Directory of Open Access Journals (Sweden)



    Full Text Available The cardiovascular responses to laryngoscopy and intubation may become hazardous in patients with compromised cardiovascular system, such as hypertension, ischemic heart diseases or cerebrovascular diseases. Attenuation of this response is extremely important. Intravenous Metoprolol 4mg was given 5 minutes before induction of Anesthesia for the attenuation of cardiovascular responses. AIM: To observe the occurrence of tachycardia hypertensive (pressor responses that occurs at the time of laryngoscopy and intubation. In the present study an attempt was made to attenuate these responses by I.V. Metoprolol 4mg. METHODS: One hundred patients of ASA physical status 1 or 2 divided into 2 groups – study and control. The study group received intravenous metoprolol 4 mg before laryngoscopy and intubation and the control group did not receive the metoprolol injection. The changes in heart rate, mean arterial pressures and rate pressure product before, during and after laryngoscopy and intubation were evaluated and compared between the two groups. The statistical analysis done using Chi-square test and two samples‘t’ test. RESULTS: The cardiovascular responses laryngoscopy and intubation were significantly attenuated (P > 0.001 by intravenous Metoprolol.

  18. Attenuation tomography using microearthquake (MEQ) data in the "A" geothermal field (United States)

    Hasanah, Mia Uswatun; Nugraha, Andri Dian; Sule, Rachmat


    Attenuation is a physical parameter of rock that can reflect the geological conditions beneath the earth's surface. We conducted attenuation tomographic imaging in the "A" geothermal field by using microearthquake (MEQ) data. We applied a method of spectral fitting to invert the t* value. For the attenuation tomographic inversion, we used the initial 3-D velocity model from the previous study in the region. Our study shows that the value of Qp, Qs and Qp/Qs ratio in the geothermal field is an important parameter for interpreting the subsurface structure. The "A" geothermal field in this study lies between several active and dormant volcanoes in West Java Province, Indonesia. This geothermal field already produces electricity of more than 220 MWe. The hydraulic stimulation has been carried out from the end of 2007 until the beginning of 2008. This experiment was carried out in order to get an understanding about the orientation of weak or fractures zones in the subsurface, so that the strategy of future exploration and well targeting could be estimated. We interpreted the joint immaging result of Qp, Qs and Qp/Qs ratio with previous seismic velocities (Vp, Vs and Vp/Vs ratio) tomography result. We can see that the high attenuation value (low Q value) and low velocity anomaly structures may associated to fluid filled rock and also fault segment.

  19. Physical activity (PA) and the disablement process

    DEFF Research Database (Denmark)

    Schultz-Larsen, Kirsten; Rahmanfard, Naghmeh; Holst, Claus


    . Among older women, the association between RPA and incidence of disability was attenuated in analyses that controlled for baseline mobility function. Thus, the association between physical activity and mortality reflected processes different from those underlying a simple relation between physical...... activity, disability and mortality. Physical activity was an ubiquitous predictor of longevity, but only for women....... community-living persons, aged 75-83 years, we evaluated the 1021 who reported no disability in basic activities of daily living. Participants were followed for a median of 8.34 years in public registers to determine onset of disability and mortality. RPA predicted mortality in older women (HR=1.77, 95%CI=1...

  20. University physics

    CERN Document Server

    Arfken, George


    University Physics provides an authoritative treatment of physics. This book discusses the linear motion with constant acceleration; addition and subtraction of vectors; uniform circular motion and simple harmonic motion; and electrostatic energy of a charged capacitor. The behavior of materials in a non-uniform magnetic field; application of Kirchhoff's junction rule; Lorentz transformations; and Bernoulli's equation are also deliberated. This text likewise covers the speed of electromagnetic waves; origins of quantum physics; neutron activation analysis; and interference of light. This publi

  1. Ultrasonic physics

    CERN Document Server

    Richardson, E G


    Ultrasonic Physics, Second Edition, provides an introduction to the fundamental principles of ultrasonic physics. The book opens with a discussion of the sources of ultrasound. This is followed by separate chapters on the properties and detection of ultrasonic radiation; measurement of propagation constants, i.e., the velocity and absorption, of ultrasound; ultrasound propagation in gases, liquids, and solids; and ultrasound propagation in aerosols, suspensions, and emulsions. The final chapter covers miscellaneous physical and physico-chemical actions, including dispersion and coagulation of

  2. Molecular physics

    CERN Document Server

    Williams, Dudley


    Methods of Experimental Physics, Volume 3: Molecular Physics focuses on molecular theory, spectroscopy, resonance, molecular beams, and electric and thermodynamic properties. The manuscript first considers the origins of molecular theory, molecular physics, and molecular spectroscopy, as well as microwave spectroscopy, electronic spectra, and Raman effect. The text then ponders on diffraction methods of molecular structure determination and resonance studies. Topics include techniques of electron, neutron, and x-ray diffraction and nuclear magnetic, nuclear quadropole, and electron spin reson

  3. Neutrino physics

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Deborah A.; /Fermilab


    The field of neutrino physics has expanded greatly in recent years with the discovery that neutrinos change flavor and therefore have mass. Although there are many neutrino physics results since the last DIS workshop, these proceedings concentrate on recent neutrino physics results that either add to or depend on the understanding of Deep Inelastic Scattering. They also describe the short and longer term future of neutrino DIS experiments.

  4. Action physics (United States)

    McGinness, Lachlan P.; Savage, C. M.


    More than a decade ago, Edwin Taylor issued a "call to action" that presented the case for basing introductory university mechanics teaching around the principle of stationary action [E. F. Taylor, Am. J. Phys. 71, 423-425 (2003)]. We report on our response to that call in the form of an investigation of the teaching and learning of the stationary action formulation of physics in a first-year university course. Our action physics instruction proceeded from the many-paths approach to quantum physics to ray optics, classical mechanics, and relativity. Despite the challenges presented by action physics, students reported it to be accessible, interesting, motivational, and valuable.

  5. Physical Activity

    DEFF Research Database (Denmark)

    Andersen, Lars Bo; Anderssen, Sigmund Alfred; Wisløff, Ulrik


    Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers.......Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers....

  6. Computational physics

    CERN Document Server

    Newman, Mark


    A complete introduction to the field of computational physics, with examples and exercises in the Python programming language. Computers play a central role in virtually every major physics discovery today, from astrophysics and particle physics to biophysics and condensed matter. This book explains the fundamentals of computational physics and describes in simple terms the techniques that every physicist should know, such as finite difference methods, numerical quadrature, and the fast Fourier transform. The book offers a complete introduction to the topic at the undergraduate level, and is also suitable for the advanced student or researcher who wants to learn the foundational elements of this important field.

  7. Calculation of the attenuation and phase displacement per unit of length due to rain composed of ellipsoidal drops (United States)

    Maggiori, D.


    All of the phenomena which influence the propagation of radiowaves at frequencies above 10 GHz (attenuation, depolarization, scintillation) can by intensified by parameters directly derived from a solution of individual scatter, naturally in addition to be meteorological elements which characterize the physical medium. The diffusion caused by rainy precipitation was studied using Mie's algorithm for rain composed of spherical drops, and Oguchi's algorithm for rain composed of drops in an ellipsoidal form with axes of rotational symmetry arrange along the vertical line of a generic reference point. Specific phase displacement and attenuation along the principal planes, propagation of radiowaves in generic polarization, and propagation with inclined axes are also considered.

  8. Measurement of 60CO gamma radiation induced attenuation in multimode step-index POF at 530 nm

    Directory of Open Access Journals (Sweden)

    Kovačević Milan S.


    Full Text Available As optical fibres are used ever more extensively in space applications, nuclear industry, medicine and high-energy physics experiments, it has become essential to investigate the influence of ionizing radiation on their characteristics. In this work, the radiation-induced attenuation at 530 nm is investigated experimentally in step-index multimode polymethyl-methacrylate plastic optical fibres exposed to low dose-rate gamma radiation. Cumulative doses ranged from 50 Gy to 500 Gy. The radiation induced attenuation has been empirically found to obey the power law RIA= aDb, where D is the total radiation dose and a and b are the constants determined by fitting.

  9. Measuring the attenuation length in liquid scintillators

    Energy Technology Data Exchange (ETDEWEB)

    Hellgartner, Dominikus; Oberauer, Lothar; Prummer, Sabrina; Sawatzki, Julia; Zimmer, Vincenz [Technische Universitaet Muenchen, Physik Departement E15, James Franck Strasse, 85748 Garching (Germany); Ulrich, Andreas [Technische Universitaet Muenchen, Physik Departement E12, James Franck Strasse, 85748 Garching (Germany)


    The next generation of liquid scintillator detectors like the proposed LENA detector or the planned JUNO detector will feature diameters of order 30 m. Due to this vast size, the optical quality of the scintillator is of crucial importance. To determine the attenuation length of liquid scintillators, an experiment with a 5 m long measurement section was set-up in the underground laboratory in Garching. The current set-up of the experiment is presented along with a discussion of the results of the first measurements. Additionally, there is an outlook towards possible upgrades of the experiment in the future.

  10. Imagined Physics

    DEFF Research Database (Denmark)

    Merritt, Timothy; Nørgaard, Mie; Laursen, Christian;


    to this book focuses on the human responses to objects that change shape in response to input from users, environment, or other circumstances. In this chapter we discuss the term "imagined physics", meaning how actuated devices are in one sense tied to their physical form, yet through the use of actuators...

  11. Sports Physicals (United States)

    ... more specific about athletic issues. During a regular physical, however, your doctor will address your overall well-being, which may include things that are unrelated to sports. You can ask your doctor to give you both types of ... if your sports physical exam doesn't reveal any problems, it's always ...

  12. Biobehavioral Correlates of Depression in Reaction to Mental and Physical Challenge (United States)


    catecholamines in response to intense exercise will diminish ( Wilmore & Costill, 2001). Acute exercise also increases ACTH and subsequently cortisol (Deuster...cortisol attenuates after an individual becomes more fit ( Wilmore & Costill, 2001). Neurohormonal response to physical challenge in depression

  13. Understanding physics

    CERN Document Server

    Cassidy, David; Rutherford, James


    Understanding Physics provides a thorough grounding in contemporary physics while placing physics into its social and historical context Based in large part on the highly respected Project Physics Course developed by two of the authors, it also integrates the results of recent pedagogical research The text thus - teaches about the basic phenomena in the physical world and the concepts developed to explain them - shows that science is a rational human endeavor with a long and continuing tradition, involving many different cultures and people - develops facility in critical thinking, reasoned argumentation, evaluation of evidence, mathematical modeling, and ethical values The treatment emphasizes not only what we know but also how we know it, why we believe it, and what effects that knowledge has - Why do we believe the Earth and planets revolve around the Sun? - Why do we believe that matter is made of atoms? - How do relativity theory and quantum mechanics alter our conception of Nature and in what ways do th...

  14. Vinpocetine attenuates lipid accumulation and atherosclerosis formation

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Yujun [Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642 (United States); Li, Jian-Dong [Center for Inflammation, Immunity and Infection, and Department of Biology, Georgia State University, Atlanta, GA 30303 (United States); Yan, Chen, E-mail: [Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642 (United States)


    Highlights: •Vinpocetine attenuates hyperlipidemia-induced atherosclerosis in a mouse model. •Vinpocetine antagonizes ox-LDL uptake and accumulation in macrophages. •Vinpocetine blocks the induction of ox-LDL receptor LOX-1 in vitro and in vivo. -- Abstract: Atherosclerosis, the major cause of myocardial infarction and stroke, is a chronic arterial disease characterized by lipid deposition and inflammation in the vessel wall. Cholesterol, in low-density lipoprotein (LDL), plays a critical role in the pathogenesis of atherosclerosis. Vinpocetine, a derivative of the alkaloid vincamine, has long been used as a cerebral blood flow enhancer for treating cognitive impairment. Recent study indicated that vinpocetine is a potent anti-inflammatory agent. However, its role in the pathogenesis of atherosclerosis remains unexplored. In the present study, we show that vinpocetine significantly reduced atherosclerotic lesion formation in ApoE knockout mice fed with a high-fat diet. In cultured murine macrophage RAW264.7 cells, vinpocetine markedly attenuated oxidized LDL (ox-LDL) uptake and foam cell formation. Moreover, vinpocetine greatly blocked the induction of ox-LDL receptor 1 (LOX-1) in cultured macrophages as well as in the LOX-1 level in atherosclerotic lesions. Taken together, our data reveal a novel role of vinpocetine in reduction of pathogenesis of atherosclerosis, at least partially through suppressing LOX-1 signaling pathway. Given the excellent safety profile of vinpocetine, this study suggests vinpocetine may be a therapeutic candidate for treating atherosclerosis.

  15. Towards a Global Upper Mantle Attenuation Model (United States)

    Karaoglu, Haydar; Romanowicz, Barbara


    Global anelastic tomography is crucial for addressing the nature of heterogeneity in the Earth's interior. The intrinsic attenuation manifests itself through dispersion and amplitude decay. These are contaminated by elastic effects such as (de)focusing and scattering. Therefore, mapping anelasticity accurately requires separation of elastic effects from the anelastic ones. To achieve this, a possible approach is to try and first predict elastic effects through the computation of seismic waveforms in a high resolution 3D elastic model, which can now be achieved accurately using numerical wavefield computations. Building upon the recent construction of such a whole mantle elastic and radially anisotropic shear velocity model (SEMUCB_WM1, French and Romanowicz, 2014), which will be used as starting model, our goal is to develop a higher resolution 3D attenuation model of the upper mantle based on full waveform inversion. As in the development of SEMUCB_WM1, forward modeling will be performed using the spectral element method, while the inverse problem will be treated approximately, using normal mode asymptotics. Both fundamental and overtone time domain long period waveforms (T>60s) will be used from a dataset of over 200 events observed at several hundred stations globally. Here we present preliminary results of synthetic tests, exploring different iterative inversion strategies.

  16. Live attenuated influenza vaccine--a review. (United States)

    Gasparini, R; Amicizia, D; Lai, P L; Panatto, D


    Owing to the variability of influenza viruses, vaccine composition needs to be up-dated annually. As many variables can influence their efficacy, vaccines are still considered "sub-optimal". Many studies have been carried out in recent years to improve vaccines. In particular, researchers and vaccine-producing corporations have focused on developing a live vaccine. Among the candidate vaccines, the strain developed by Maassab has recently been licensed in the USA and Europe, after extensive investigation. This vaccine is safe and well tolerated, and has shown very good genetic stability. Although vaccine recipients are able to spread the virus, transmission to close contacts is practically non-existent. Studies on cold-adapted attenuated influenza vaccines have demonstrated that such vaccines are effective, and sometimes more effective than inactivated influenza vaccines. Cold-adapted attenuated influenza vaccines therefore appear to be an important weapon against influenza. However, a more widespread use of these vaccines is to be recommended, especially in children, as the more acceptable way of administration can favour parental compliance.

  17. Surface Wave Attenuation in the Tibetan Plateau from Ambient Noise (United States)


    R. Weaver, and X.N. Yang, Surface wave attenuation in Tibetan Plateau from ambient noise, Monitoring Research Review, Albuquerque, NM, 2012...AFRL-RV-PS- TR-2015-0150 AFRL-RV-PS- TR-2015-0150 SURFACE WAVE ATTENUATION IN THE TIBETAN PLATEAU FROM AMBIENT NOISE University of Illinois at...DATES COVERED (From - To) 01 May 2012 to 31 Aug 2015 4. TITLE AND SUBTITLE Surface Wave Attenuation in the Tibetan Plateau from Ambient Noise 5a

  18. A wideband IM3 cancellation technique for CMOS attenuators

    NARCIS (Netherlands)

    Cheng, W.; Oude Alink, M.S.; Annema, A.J.; Wienk, G.J.M.; Nauta, B.


    A highly linear P attenuator system using a wideband IM3 cancellation technique is presented that provides 4 discrete attenuation levels with 6dB spacing for DC-5GHz. For the whole band, S11<-14dB, attenuation flatness<1.6dB, +10dBm input P1dB and +26dBm IIP3 are achieved. For the TV band (0.1Gz-1.2

  19. Statistical physics

    CERN Document Server

    Wannier, Gregory H


    Until recently, the field of statistical physics was traditionally taught as three separate subjects: thermodynamics, statistical mechanics, and kinetic theory. This text, a forerunner in its field and now a classic, was the first to recognize the outdated reasons for their separation and to combine the essentials of the three subjects into one unified presentation of thermal physics. It has been widely adopted in graduate and advanced undergraduate courses, and is recommended throughout the field as an indispensable aid to the independent study and research of statistical physics.Designed for

  20. Interpreting Physics

    CERN Document Server

    MacKinnon, Edward


    This book is the first to offer a systematic account of the role of language in the development and interpretation of physics. An historical-conceptual analysis of the co-evolution of mathematical and physical concepts leads to the classical/quatum interface. Bohrian orthodoxy stresses the indispensability of classical concepts and the functional role of mathematics. This book analyses ways of extending, and then going beyond this orthodoxy orthodoxy. Finally, the book analyzes how a revised interpretation of physics impacts on basic philosophical issues: conceptual revolutions, realism, and r

  1. Neutrino physics

    CERN Document Server

    Hernandez, P


    This is the writeup of the lectures on neutrino physics delivered at various schools: TASI and Trieste in 2013 and the CERN-Latin American School in 2015. The topics discussed in this lecture include: general properties of neutrinos in the SM, the theory of neutrino masses and mixings (Dirac and Majorana), neutrino oscillations both in vacuum and in matter, as well as an overview of the experimental evidence for neutrino masses and of the prospects in neutrino oscillation physics. We also briefly review the relevance of neutri- nos in leptogenesis and in beyond-the-Standard-Model physics.

  2. Plasma physics

    CERN Document Server

    Drummond, James E


    A historic snapshot of the field of plasma physics, this fifty-year-old volume offers an edited collection of papers by pioneering experts in the field. In addition to assisting students in their understanding of the foundations of classical plasma physics, it provides a source of historic context for modern physicists. Highly successful upon its initial publication, this book was the standard text on plasma physics throughout the 1960s and 70s.Hailed by Science magazine as a ""well executed venture,"" the three-part treatment ranges from basic plasma theory to magnetohydrodynamics and microwa

  3. Higgs Physics

    CERN Document Server

    Grojean, C


    The cause of the screening of the weak interactions at long distances puzzled the high-energy community for more nearly half a century. With the discovery of the Higgs boson a new era started with direct experimental information on the physics behind the breaking of the electroweak symmetry. This breaking plays a fundamental role in our understanding of particle physics and sits at the high-energy frontier beyond which we expect new physics that supersedes the Standard Model. The Higgs boson (inclusive and differential) production and decay rates offer a new way to probe this frontier.

  4. Complex systems: physics beyond physics

    CERN Document Server

    Holovatch, Yurij; Thurner, Stefan


    Complex systems are characterized by specific time-dependent interactions among their many constituents. As a consequence they often manifest rich, non-trivial and unexpected behavior. Examples arise both in the physical and non-physical world. The study of complex systems forms a new interdisciplinary research area that cuts across physics, biology, ecology, economics, sociology, and the humanities. In this paper we review the essence of complex systems from a physicist's point of view, and try to clarify what makes them conceptually different from systems that are traditionally studied in physics. Our goal is to demonstrate how the dynamics of such systems may be conceptualized in quantitative and predictive terms by extending notions from statistical physics and how they can often be captured in a framework of co-evolving multiplex network structures. We mention three areas of complex-systems science that are currently studied extensively, the science of cities, dynamics of societies, and the representatio...

  5. Importance of Attenuation Correction (AC for Small Animal PET Imaging

    Directory of Open Access Journals (Sweden)

    Henrik H. El Ali


    Full Text Available The purpose of this study was to investigate whether a correction for annihilation photon attenuation in small objects such as mice is necessary. The attenuation recovery for specific organs and subcutaneous tumors was investigated. A comparison between different attenuation correction methods was performed. Methods: Ten NMRI nude mice with subcutaneous implantation of human breast cancer cells (MCF-7 were scanned consecutively in small animal PET and CT scanners (MicroPETTM Focus 120 and ImTek’s MicroCATTM II. CT-based AC, PET-based AC and uniform AC methods were compared. Results: The activity concentration in the same organ with and without AC revealed an overall attenuation recovery of 9–21% for MAP reconstructed images, i.e., SUV without AC could underestimate the true activity at this level. For subcutaneous tumors, the attenuation was 13 ± 4% (9–17%, for kidneys 20 ± 1% (19–21%, and for bladder 18 ± 3% (15–21%. The FBP reconstructed images showed almost the same attenuation levels as the MAP reconstructed images for all organs. Conclusions: The annihilation photons are suffering attenuation even in small subjects. Both PET-based and CT-based are adequate as AC methods. The amplitude of the AC recovery could be overestimated using the uniform map. Therefore, application of a global attenuation factor on PET data might not be accurate for attenuation correction.

  6. Attenuation characteristics of ground motions in northern China

    Institute of Scientific and Technical Information of China (English)

    黄玉龙; 赵兴权; 罗奇峰


    Four recently developed attenuation models are calibrated by using a very limited amount of strong motion data recorded in China. The research shows that the attenuation characteristics of the earthquake shaking in northern China are similar to those in the western US. The supporting evidence includes Q factors, preliminary results of kappa values, stress drop,shear wave velocity profile in the shallow earth crust, areas enclosed by the isoseismals of Modified Mercalli Intensity V. From these comparisons of different attenuation models, it is recommended that the Crouse and McGuire spectral attenuation model could possibly be used for northern China.

  7. Damping factor estimation using spin wave attenuation in permalloy film

    Energy Technology Data Exchange (ETDEWEB)

    Manago, Takashi, E-mail: [Department of Applied Physics, Fukuoka University, 8-19-1 Nanakuma, Jonan, Fukuoka 814-0180 (Japan); Yamanoi, Kazuto [Department of Physics, Kyushu University, 6-10-1 Hakozaki, Fukuoka 812-8581 (Japan); Kasai, Shinya; Mitani, Seiji [National Institute for Materials Science (NIMS), Tsukuba, Ibaraki 305-0047 (Japan)


    Damping factor of a Permalloy (Py) thin film is estimated by using the magnetostatic spin wave propagation. The attenuation lengths are obtained by the dependence of the transmission intensity on the antenna distance, and decrease with increasing magnetic fields. The relationship between the attenuation length, damping factor, and external magnetic field is derived theoretically, and the damping factor was determined to be 0.0063 by fitting the magnetic field dependence of the attenuation length, using the derived equation. The obtained value is in good agreement with the general value of Py. Thus, this estimation method of the damping factor using spin waves attenuation can be useful tool for ferromagnetic thin films.

  8. [Usefulness of attenuation correction with transmission source in myocardial SPECT]. (United States)

    Murakawa, Keizo; Katafuchi, Tetsuro; Nishimura, Yoshihiro; Enomoto, Naoyuki; Sago, Masayoshi; Oka, Hisashi


    Attenuation correction in SPECT has been used for uniformly absorptive objects like the head. On the other hand, it has seldom been applied to nonuniform absorptive objects like the heart and surrounding lungs because of the difficulty and inaccuracy of data processing. However, since attenuation correction using a transmission source recently became practical, we were able to apply this method to a nonuniform absorptive object. Therefore, we evaluated the usefulness of this attenuation correction system with a transmission source in myocardial SPECT. The dose linearity, defect/normal ratio using a myocardial phantom, and myocardial count distribution in clinical cases was examined with and without the attenuation correction system. We found that all data processed with attenuation correction were better than those without attenuation correction. For example, in myocardial count distribution, while there was a difference between men and women without attenuation correction, which was considered to be caused by differences in body shape, after processing with attenuation correction, myocardial count distribution was almost the same in all cases. In conclusion, these results suggested that attenuation correction with a transmission source was useful in myocardial SPECT.

  9. Enhanced Attenuation Technologies: Passive Soil Vapor Extraction

    Energy Technology Data Exchange (ETDEWEB)

    Vangelas, K.; Looney, B.; Kamath, R.; Adamson, D.; Newell, C.


    Passive soil vapor extraction (PSVE) is an enhanced attenuation (EA) approach that removes volatile contaminants from soil. The extraction is driven by natural pressure gradients between the subsurface and atmosphere (Barometric Pumping), or by renewable sources of energy such as wind or solar power (Assisted PSVE). The technology is applicable for remediating sites with low levels of contamination and for transitioning sites from active source technologies such as active soil vapor extraction (ASVE) to natural attenuation. PSVE systems are simple to design and operate and are more cost effective than active systems in many scenarios. Thus, PSVE is often appropriate as an interim-remedial or polishing strategy. Over the past decade, PSVE has been demonstrated in the U.S. and in Europe. These demonstrations provide practical information to assist in selecting, designing and implementing the technology. These demonstrations indicate that the technology can be effective in achieving remedial objectives in a timely fashion. The keys to success include: (1) Application at sites where the residual source quantities, and associated fluxes to groundwater, are relatively low; (2) Selection of the appropriate passive energy source - barometric pumping in cases with a deep vadose zone and barrier (e.g., clay) layers that separate the subsurface from the atmosphere and renewable energy assisted PSVE in other settings and where higher flow rates are required. (3) Provision of sufficient access to the contaminated vadose zones through the spacing and number of extraction wells. This PSVE technology report provides a summary of the relevant technical background, real-world case study performance, key design and cost considerations, and a scenario-based cost evaluation. The key design and cost considerations are organized into a flowchart that dovetails with the Enhanced Attenuation: Chlorinated Organics Guidance of the Interstate Technology and Regulatory Council (ITRC). The PSVE

  10. Neighborhood context and immigrant children's physical activity. (United States)

    Brewer, Mackenzie; Kimbro, Rachel Tolbert


    Physical activity is an important determinant of obesity and overall health for children, but significant race/ethnic and nativity disparities exist in the amount of physical activity that children receive, with immigrant children particularly at risk for low levels of physical activity. In this paper, we examine and compare patterns in physical activity levels for young children of U.S.-born and immigrant mothers from seven race/ethnic and nativity groups, and test whether physical activity is associated with subjective (parent-reported) and objective (U.S. Census) neighborhood measures. The neighborhood measures include parental-reported perceptions of safety and physical and social disorder and objectively defined neighborhood socioeconomic disadvantage and immigrant concentration. Using restricted, geo-coded Early Childhood Longitudinal Study-Kindergarten (ECLS-K) data (N = 17,510) from 1998 to 1999 linked with U.S. Census 2000 data for the children's neighborhoods, we utilize zero-inflated Poisson (ZIP) models to predict the odds of physical inactivity and expected days of physical activity for kindergarten-aged children. Across both outcomes, foreign-born children have lower levels of physical activity compared to U.S.-born white children. This disparity is not attenuated by a child's socioeconomic, family, or neighborhood characteristics. Physical and social disorder is associated with higher odds of physical inactivity, while perceptions of neighborhood safety are associated with increased expected days of physical activity, but not with inactivity. Immigrant concentration is negatively associated with both physical activity outcomes, but its impact on the probability of physical inactivity differs by the child's race/ethnic and nativity group, such that it is particularly detrimental for U.S.-born white children's physical activity. Research interested in improving the physical activity patterns of minority and second-generation immigrant children should

  11. Physics olympiad (United States)

    Five high school physics students will represent the U.S. at the 20th International Physics Olympiad, July 14-25 in Warsaw, Poland. The Olympiad has been held annually since 1967; this is the fourth year the U.S. will compete. The American Association of Physics Teachers administers the U.S. program; AGU is a principal sponsoring organization of the Olympiad, as is the American Institute of Physics.The students are Derrick Bass, North Miami Beach High School, Miami Beach, Fla.; Steven Gubser, Cherry Creek High School, Englewood, Colo.; Jason Jacobs, Baldwin Senior High School, Baldwin, N.Y.; Jessica Millar, West High School, Madison, Wise; and James Sarvis, Thomas Jefferson High School, Alexandria, Va.

  12. Physical Abuse (United States)

    ... be acquaintances, sons, daughters, grandchildren, or others. Physical abuse that is perpetrated by spouses or intimate partners in order to gain power and control over the victim is described in ...

  13. Magic Physics? (United States)

    Featonby, David


    This article examines several readily available "magic tricks" which base their "trickery" on physics principles, and questions the use of the word "magic" in the 21st century, both in popular children's science and in everyday language. (Contains 18 figures.)

  14. Engineering physics

    CERN Document Server

    Mukherji, Uma


    ENGINEERING PHYSICS is designed as a textbook for first year engineering students of a two semester course in Applied Physics according to new revised syllabus. However the scope of this book is not only limited to undergraduate engineering students and science students, it can also serve as a reference book for practicing scientists.Advanced technological topics like LCD, Squid, Maglev system, Electron microscopes, MRI, Photonics - Photonic fibre, Nano-particles, CNT, Quantum computing etc., are explained with basic underlying principles of Physics.This text explained following topics with numerous solved, unsolved problems and questions from different angles. Part-I contains crystal structure, Liquid crystal, Thermo-electric effect, Thermionic emission, Ultrasonic, Acoustics, semiconductor and magnetic materials. Whereas Part-2 contains Optics, X-rays, Electron optics, Dielectric materials, Quantum Physics and Schrodinger wave equation, Laser, Fibre-optics and Holography, Radio-activity, Super-conductivity,...

  15. Physical mathematics

    CERN Document Server

    Cahill, Kevin


    Unique in its clarity, examples and range, Physical Mathematics explains as simply as possible the mathematics that graduate students and professional physicists need in their courses and research. The author illustrates the mathematics with numerous physical examples drawn from contemporary research. In addition to basic subjects such as linear algebra, Fourier analysis, complex variables, differential equations and Bessel functions, this textbook covers topics such as the singular-value decomposition, Lie algebras, the tensors and forms of general relativity, the central limit theorem and Kolmogorov test of statistics, the Monte Carlo methods of experimental and theoretical physics, the renormalization group of condensed-matter physics and the functional derivatives and Feynman path integrals of quantum field theory.

  16. Statistical physics

    CERN Document Server

    Sadovskii, Michael V


    This volume provides a compact presentation of modern statistical physics at an advanced level. Beginning with questions on the foundations of statistical mechanics all important aspects of statistical physics are included, such as applications to ideal gases, the theory of quantum liquids and superconductivity and the modern theory of critical phenomena. Beyond that attention is given to new approaches, such as quantum field theory methods and non-equilibrium problems.

  17. Neutrino Physics

    CERN Document Server

    Xing, Zhi-Zhong


    I give a theoretical overview of some basic properties of massive neutrinos in these lectures. Particular attention is paid to the origin of neutrino masses, the pattern of lepton flavor mixing, the feature of leptonic CP violation and the electromagnetic properties of massive neutrinos. I highlight the TeV seesaw mechanisms as a possible bridge between neutrino physics and collider physics in the era characterized by the Large Hadron Collider.

  18. Nuclear Physics (United States)

    Contents: V Dinucleons, published in The Physical Review , v93 n4 p908-909, 15 Feb 1954; Concentration of a Cyclotron Beam by Strong Focusing Lenses...published in The Review of Scientific Instruments, v25 n4 p365-367, Apr 1954; and Photon Splitting in a Nuclear Electrostatic Field, published in The Physical Review , v94 n2 p367-368, 15 Apr 1954.

  19. Ultrasound physics. (United States)

    Shriki, Jesse


    Bedside ultrasound has become an important modality for obtaining critical information in the acute care of patients. It is important to understand the physics of ultrasound in order to perform and interpret images at the bedside. The physics of both continuous wave and pulsed wave sound underlies diagnostic ultrasound. The instrumentation, including transducers and image processing, is important in the acquisition of appropriate sonographic images. Understanding how these concepts interplay with each other enables practitioners to obtain the best possible images.

  20. The use of calibration standards and the correction for sample self-attenuation in gamma-ray nondestructive assay

    Energy Technology Data Exchange (ETDEWEB)

    Parker, J.L.


    The efficient use of appropriate calibration standards and the correction for the attenuation of the gamma rays within an assay sample by the sample itself are two important and closely related subjects in gamma-ray nondestructive assay. Much research relating to those subjects has been done in the Nuclear Safeguards Research and Development program at the Los Alamos National Laboratory since 1970. This report brings together most of the significant results of that research. Also discussed are the nature of appropriate calibration standards and the necessary conditions on the composition, size, and shape of the samples to allow accurate assays. Procedures for determining the correction for the sample self-attenuation are described at length including both general principles and several specific useful cases. The most useful concept is that knowing the linear attenuation coefficient of the sample (which can usually be determined) and the size and shape of the sample and its position relative to the detector permits the computation of the correction factor for the self-attenuation. A major objective of the report is to explain how the procedures for determining the self-attenuation correction factor can be applied so that calibration standards can be entirely appropriate without being particularly similar, either physically or chemically, to the items to be assayed. This permits minimization of the number of standards required to assay items with a wide range of size, shape, and chemical composition.

  1. Use of calibration standards and the correction for sample self-attenuation in gamma-ray nondestructive assay

    Energy Technology Data Exchange (ETDEWEB)

    Parker, J.L.


    The efficient use of appropriate calibration standards and the correction for the attenuation of the gamma rays within an assay sample by the sample itself are two important and closely related subjects in gamma-ray nondestructive assay. Much research relating to those subjects has been done in the Nuclear Safeguards Research and Development program at the Los Alamos National Laboratory since 1970. This report brings together most of the significant results of that research. Also discussed are the nature of appropriate calibration standards and the necessary conditions on the composition, size, and shape of the samples to allow accurate assays. Procedures for determining the correction for the sample self-attenuation are described at length including both general principles and several specific useful cases. The most useful concept is that knowing the linear attenuation coefficient of the sample (which can usually be determined) and the size and shape of the sample and its position relative to the detector permits the computation of the correction factor for the self-attenuation. A major objective of the report is to explain how the procedures for determining the self-attenuation correction factor can be applied so that calibration standards can be entirely appropriate without being particularly similar, either physically or chemically, to the items to be assayed. This permits minimization of the number of standards required to assay items with a wide range of size, shape, and chemical composition. 17 references, 18 figures, 2 tables.

  2. Gas sensor with attenuated drift characteristic (United States)

    Chen, Ing-Shin [Danbury, CT; Chen, Philip S. H. [Bethel, CT; Neuner, Jeffrey W [Bethel, CT; Welch, James [Fairfield, CT; Hendrix, Bryan [Danbury, CT; Dimeo, Jr., Frank [Danbury, CT


    A sensor with an attenuated drift characteristic, including a layer structure in which a sensing layer has a layer of diffusional barrier material on at least one of its faces. The sensor may for example be constituted as a hydrogen gas sensor including a palladium/yttrium layer structure formed on a micro-hotplate base, with a chromium barrier layer between the yttrium layer and the micro-hotplate, and with a tantalum barrier layer between the yttrium layer and an overlying palladium protective layer. The gas sensor is useful for detection of a target gas in environments susceptible to generation or incursion of such gas, and achieves substantial (e.g., >90%) reduction of signal drift from the gas sensor in extended operation, relative to a corresponding gas sensor lacking the diffusional barrier structure of the invention

  3. Attenuation of ultrasonic waves in rolled metals (United States)

    Yang, Liyong; Turner, Joseph A.


    Scattering of ultrasonic waves in polycrystals with texture is studied in this article. The attenuations of the three wave modes are determined as a function of dimensionless frequency and propagation direction, respectively, for given orientation distribution coefficients (ODCs). The calculation is done in the case of a statistically orthorhombic sample made up of cubic crystallites. The wave propagation and scattering model is formulated by the Dyson equation using an anisotropic Green's function approach. Within the limits of the first-order smoothing approximation, the Dyson equation is solved in the spatial Fourier transform domain. The results presented are shown to be directional dependent, frequency dependent, and especially dependent on the texture coefficients (ODCs) for the quasilongitudinal and two quasishear waves. The theoretical results presented may be used to improve the understanding of the microstructure during recrystallization processes. .

  4. Hollow antiresonant fibers with reduced attenuation. (United States)

    Belardi, Walter; Knight, Jonathan C


    An improved design for hollow antiresonant fibers (HAFs) is presented. It consists of adding extra antiresonant glass elements within the air cladding region of an antiresonant hollow-core fiber. We use numerical simulations to compare fiber structures with and without the additional cladding elements in the near- and mid-IR regimes. We show that realizable fiber structures can provide greatly improved performance in terms of leakage and bending losses compared to previously reported antiresonant fibers. At mid-IR wavelengths, the adoption of this novel fiber design will lead to HAFs with reduced bending losses. In the near-IR, this design could lead to the fabrication of HAFs with very low attenuation.

  5. Gene × physical activity interactions in obesity

    DEFF Research Database (Denmark)

    Ahmad, Shafqat; Rukh, Gull; Varga, Tibor V


    -administered questionnaires. Multiplicative interactions between the GRS and physical activity on BMI were tested in linear and logistic regression models in each cohort, with adjustment for age, age(2), sex, study center (for multicenter studies), and the marginal terms for physical activity and the GRS. These results were......Numerous obesity loci have been identified using genome-wide association studies. A UK study indicated that physical activity may attenuate the cumulative effect of 12 of these loci, but replication studies are lacking. Therefore, we tested whether the aggregate effect of these loci is diminished...... in adults of European ancestry reporting high levels of physical activity. Twelve obesity-susceptibility loci were genotyped or imputed in 111,421 participants. A genetic risk score (GRS) was calculated by summing the BMI-associated alleles of each genetic variant. Physical activity was assessed using self...

  6. Dose reduction technique using a combination of a region of interest (ROI) material x-ray attenuator and spatially different temporal filtering for fluoroscopic interventions (United States)

    Swetadri Vasan, S. N.; Panse, A.; Jain, A.; Sharma, P.; Ionita, Ciprian N.; Titus, A. H.; Cartwright, A. N.; Bednarek, D. R.; Rudin, S.


    We demonstrate a novel approach for achieving patient dose savings during image-guided neurovascular interventions, involving a combination of a material x-ray region of interest (ROI) attenuator and a spatially different ROI temporal filtering technique. The part of the image under the attenuator is reduced in dose but noisy and less bright due to fewer x-ray quanta reaching the detector, as compared to the non-attenuating (or less attenuating) region. First the brightness is equalized throughout the image by post processing and then a temporal filter with higher weights is applied to the high attenuating region to reduce the noise, at the cost of increased lag; however, in the regions where less attenuation is present, a lower temporal weight is needed and is applied to preserve temporal resolution. A simulation of the technique is first presented on an actual image sequence obtained from an endovascular image guided interventional (EIGI) procedure. Then the actual implementation of the technique with a physical ROI attenuator is presented. Quantitative analysis including noise analysis and integral dose calculations are presented to validate the proposed technique.

  7. Evidence of oxidative attenuation of auxin signalling. (United States)

    Peer, Wendy Ann; Cheng, Yan; Murphy, Angus S


    Indole-3-acetic acid (IAA) is the principle auxin in Arabidopsis and is synthesized primarily in meristems and nodes. Auxin is transported to distal parts of the plant in response to developmental programming or environmental stimuli to activate cell-specific responses. As with any signalling event, the signal must be attenuated to allow the system to reset. Local auxin accumulations are thus reduced by conjugation or catabolism when downstream responses have reached their optima. In most cell types, localized auxin accumulation increases both reactive oxygen species (ROS) and an irreversible catabolic product 2-oxindole-3-acid acid (oxIAA). oxIAA is inactive and does not induce expression of the auxin-responsive reporters DR5 or 2XD0. Here it is shown that oxIAA is not transported from cell to cell, although it appears to be a substrate for the ATP-binding cassette subfamily G (ABCG) transporters that are positioned primarily on the outer lateral surface of the root epidermis. However, oxIAA and oxIAA-Glc levels are higher in ABCB mutants that accumulate auxin due to defective cellular export. Auxin-induced ROS production appears to be at least partially mediated by the NAD(P)H oxidase RbohD. oxIAA levels are higher in mutants that lack ROS-scavenging flavonoids (tt4) and are lower in mutants that accumulate excess flavonols (tt3). These data suggest a model where IAA signalling is attenuated by IAA catabolism to oxIAA. Flavonoids appear to buffer ROS accumulations that occur with localized increases in IAA. This buffering of IAA oxidation would explain some growth responses observed in flavonoid-deficient mutants that cannot be explained by their established role in partially inhibiting auxin transport.

  8. A miniaturized reconfigurable broadband attenuator based on RF MEMS switches (United States)

    Guo, Xin; Gong, Zhuhao; Zhong, Qi; Liang, Xiaotong; Liu, Zewen


    Reconfigurable attenuators are widely used in microwave measurement instruments. Development of miniaturized attenuation devices with high precision and broadband performance is required for state-of-the-art applications. In this paper, a compact 3-bit microwave attenuator based on radio frequency micro-electro-mechanical system (RF MEMS) switches and polysilicon attenuation modules is presented. The device comprises 12 ohmic contact MEMS switches, π-type polysilicon resistive attenuation modules and microwave compensate structures. Special attention was paid to the design of the resistive network, compensate structures and system simulation. The device was fabricated using micromachining processes compatible with traditional integrated circuit fabrication processes. The reconfigurable attenuator integrated with RF MEMS switches and resistive attenuation modules was successfully fabricated with dimensions of 2.45  ×  4.34  ×  0.5 mm3, which is 1/1000th of the size of a conventional step attenuator. The measured RF performance revealed that the attenuator provides 10-70 dB attenuation at 10 dB intervals from 0.1-20 GHz with an accuracy better than  ±1.88 dB at 60 dB and an error of less than 2.22 dB at 10 dB. The return loss of each state of the 3-bit attenuator was better than 11.95 dB (VSWR  <  1.71) over the entire operating band.

  9. Plasma physics

    CERN Document Server

    Cairns, R A


    This book is intended as an introduction to plasma physics at a level suitable for advanced undergraduates or beginning postgraduate students in physics, applied mathematics or astrophysics. The main prerequisite is a knowledge of electromagnetism and of the associated mathematics of vector calculus. SI units are used throughout. There is still a tendency amongst some plasma physics researchers to· cling to C.g.S. units, but it is the author's view that universal adoption of SI units, which have been the internationally agreed standard since 1960, is to be encouraged. After a short introductory chapter, the basic properties of a plasma con­ cerning particle orbits, fluid theory, Coulomb collisions and waves are set out in Chapters 2-5, with illustrations drawn from problems in nuclear fusion research and space physics. The emphasis is on the essential physics involved and (he theoretical and mathematical approach has been kept as simple and intuitive as possible. An attempt has been made to draw attention t...

  10. Doxycycline Attenuated Pulmonary Fibrosis Induced by Bleomycin in Mice


    Fujita, Masaki; Ye, Qing; Ouchi, Hiroshi; Harada, Eiji; Inoshima, Ichiro; Kuwano, Kazuyoshi; Nakanishi, Yoichi


    The administration of doxycycline prior to bleomycin in mice attenuated pulmonary fibrosis. Bronchoalveolar neutrophil influx and gelatinase activity, but not caseinolytic activity, were attenuated by doxycycline. Established fibrosis was not affected by doxycycline. Thus, doxycycline might be useful for slowing down pulmonary fibrosis by biological activity other than antibacterial activity.

  11. 16 CFR 1203.17 - Impact attenuation test. (United States)


    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Impact attenuation test. 1203.17 Section... SAFETY STANDARD FOR BICYCLE HELMETS The Standard § 1203.17 Impact attenuation test. (a) Impact test... the acceleration of the test headform during impact. Acceleration is measured with a...

  12. The attenuation anisotropy of mudstones and shales in subsurface formations

    Institute of Scientific and Technical Information of China (English)

    SHI Ge; DENG Jixin


    We have measured the relationships in the laboratorial condition between the attenuation in three samples of mudstones and shales as well as two samples of layered sandstones and the alteration in direction, confining pressure and pore fluid. The relative contributions of different attenuation mechanisms are also discussed. Studies show that the attenuation in dry and saturated samples is strongly related to pressure and direction. The attenuation coefficient of P-wave propagating parallel to bedding (PH) is less than that of P-wave propagating vertical to bedding (PV), while the attenuation coefficient of S-wave both propagating and vibrating parallel to bedding (SH) and that of S-wave propagating vertical to bedding while vibrating parallel to bedding (SV1) are less than that of S-wave propagating parallel to bedding while vibrating vertical to bedding (SV). Under oil saturated conditions, the Biot flow attenuation acts as the dominant mechanism for waves propagating parallel to bedding, while the frame anelastic attenuation and squirt flow attenuation seem to play important roles in condition of propagation vertical to bedding.

  13. Wave attenuation in mangroves; a quantitative approach to field observations

    NARCIS (Netherlands)

    Horstman, E.M.; Dohmen-Janssen, C.M.; Narra, P.M.F.; Berg, van den N.J.F.; Siemerink, M.; Hulscher, S.J.M.H.


    Coastal mangroves, dwelling at the interface between land and sea, provide an important contribution to reducing risk from coastal hazards by attenuating incident waves and by trapping and stabilizing sediments. This paper focusses on relations between vegetation densities, wave attenuation rates, s

  14. Light attenuation characteristics of glacially-fed lakes (United States)

    Rose, Kevin C.; Hamilton, David P.; Williamson, Craig E.; McBride, Chris G.; Fischer, Janet M.; Olson, Mark H.; Saros, Jasmine E.; Allan, Mathew G.; Cabrol, Nathalie


    Transparency is a fundamental characteristic of aquatic ecosystems and is highly responsive to changes in climate and land use. The transparency of glacially-fed lakes may be a particularly sensitive sentinel characteristic of these changes. However, little is known about the relative contributions of glacial flour versus other factors affecting light attenuation in these lakes. We sampled 18 glacially-fed lakes in Chile, New Zealand, and the U.S. and Canadian Rocky Mountains to characterize how dissolved absorption, algal biomass (approximated by chlorophyll a), water, and glacial flour contributed to attenuation of ultraviolet radiation (UVR) and photosynthetically active radiation (PAR, 400-700 nm). Variation in attenuation across lakes was related to turbidity, which we used as a proxy for the concentration of glacial flour. Turbidity-specific diffuse attenuation coefficients increased with decreasing wavelength and distance from glaciers. Regional differences in turbidity-specific diffuse attenuation coefficients were observed in short UVR wavelengths (305 and 320 nm) but not at longer UVR wavelengths (380 nm) or PAR. Dissolved absorption coefficients, which are closely correlated with diffuse attenuation coefficients in most non-glacially-fed lakes, represented only about one quarter of diffuse attenuation coefficients in study lakes here, whereas glacial flour contributed about two thirds across UVR and PAR. Understanding the optical characteristics of substances that regulate light attenuation in glacially-fed lakes will help elucidate the signals that these systems provide of broader environmental changes and forecast the effects of climate change on these aquatic ecosystems.

  15. Ultrasonic velocity and attenuation anisotropy of shales, Whitby, United Kingdom

    NARCIS (Netherlands)

    Zhubayev, A.; Houben, M.E.; Smeulders, D.M.J.; Barnhoorn, A.


    We have conducted ultrasonic experiments, between 0.3 and 1 MHz, to measure velocity and attenuation (Q−1) anisotropy of P- and S-waves in dry Whitby Mudstone samples as a function of stress. We found the degree of anisotropy to be as large as 70% for velocity and attenuation. The sensitivity of P-w

  16. Ultrasonic velocity and attenuation anisotropy of shales, Whitby, United Kingdom

    NARCIS (Netherlands)

    Zhubayev, Alimzhan; Houben, M.E.; Smeulders, David; Barnhoorn, A.


    We have conducted ultrasonic experiments, between 0.3 and 1 MHz, to measure velocity and attenuation (Q−1) anisotropy of P- and S-waves in dry Whitby Mudstone samples as a function of stress. We found the degree of anisotropy to be as large as 70% for velocity and attenuation. The sensitivity of P-w

  17. Attenuated radon transform: theory and application in medicine and biology

    Energy Technology Data Exchange (ETDEWEB)

    Gullberg, G.T.


    A detailed analysis is given of the properties of the attenuated Radon transform and of how increases in photon attenuation influence the numerical accuracy and computation efficiency of iterative and convolution algorithms used to determine its inversion. The practical applications for this work involve quantitative assessment of the distribution of injected radiopharmaceuticals and radionuclides in man and animals for basic physiological and biochemical studies as well as clinical studies in nuclear medicine. A mathematical structure is developed using function theory and the theory of linear operators on Hilbert spaces which lends itself to better understanding the spectral properties of the attenuated Radon transform. The continuous attenuated Radon transform reduces to a matrix operator for discrete angular and lateral sampling, and the reconstruction problem reduces to a system of linear equations. For the situation of variable attenuation coefficient frequently found in nuclear medicine applications of imaging the heart and chest, the procedure developed in this thesis involves iterative techniques of performing the generalized inverse. For constant attenuation coefficient less than 0.15 cm/sup -1/, convolution methods can reliably reconstruct a 30 cm object with 0.5 cm resolution. However, for high attenuation coefficients or for the situation where there is variable attenuation such as reconstruction of distribution of isotopes in the heart, iterative techniques developed in this thesis give the best results. (ERB)

  18. Flux attenuation at NREL's High-Flux Solar Furnace (United States)

    Bingham, Carl E.; Scholl, Kent L.; Lewandowski, Allan A.


    The High-Flux Solar Furnace (HFSF) at the National Renewable Energy Laboratory (NREL) has a faceted primary concentrator and a long focal-length-to-diameter ratio (due to its off-axis design). Each primary facet can be aimed individually to produce different flux distributions at the target plane. Two different types of attenuators are used depending on the flux distribution. A sliding-plate attenuator is used primarily when the facets are aimed at the same target point. The alternate attenuator resembles a venetian blind. Both attenuators are located between the concentrator and the focal point. The venetian-blind attenuator is primarily used to control the levels of sunlight failing on a target when the primary concentrators are not focused to a single point. This paper will demonstrate the problem of using the sliding-plate attenuator with a faceted concentrator when the facets are not aimed at the same target point. We will show that although the alternate attenuator necessarily blocks a certain amount of incoming sunlight, even when fully open, it provides a more even attenuation of the flux for alternate aiming strategies.

  19. Ultrasound attenuation dependence on air compression or expansion processes

    NARCIS (Netherlands)

    Jakevicius, L.; Demcenko, A.; Mardosaite, R.


    In this work variation of ultrasonic attenuation coefficient is analyzed in terms of air compression or expansion processes. In closed spaces changing air volume, the ultrasound attenuation coefficient depends on thermodynamic processes which occur during the air volume change. Two limiting cases ar

  20. Excess attenuation of an acoustic beam by turbulence. (United States)

    Pan, Naixian


    A theory based on the concept of a spatial sinusoidal diffraction grating is presented for the estimation of the excess attenuation in an acoustic beam. The equation of the excess attenuation coefficient shows that the excess attenuation of acoustic beam not only depends on the turbulence but also depends on the application parameters such as the beam width, the beam orientation and whether for forward propagation or back scatter propagation. Analysis shows that the excess attenuation appears to have a frequency dependence of cube-root. The expression for the excess attenuation coefficient has been used in the estimations of the temperature structure coefficient, C(T)2, in sodar sounding. The correction of C(T)2 values for excess attenuation reduces their errors greatly. Published profiles of temperature structure coefficient and the velocity structure coefficient in convective conditions are used to test our theory, which is compared with the theory by Brown and Clifford. The excess attenuation due to scattering from turbulence and atmospheric absorption are both taken into account in sodar data processing for deducing the contribution of the lower atmosphere to seeing, which is the sharpness of a telescope image determined by the degree of turbulence in the Earth's atmosphere. The comparison between the contributions of the lowest 300-m layer to seeing with that of the whole atmosphere supports the reasonableness of our estimation of excess attenuation.

  1. Periportal low-attenuation: a CT sign of lymphatic obstruction

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Hoon; Kim, Chong Soo; Yang, Doo Hyun; Lee, Sang Yong; Lee, Young Whan; Chung, Gyung Ho; Han, Young Min; Sohn, Myung Hee; Choi, Ki Chul [Chonbuk National University College of Medicine, Jeonju (Korea, Republic of)


    Periportal low attenuation, defined as a low attenuation rim around the portal vein and its branches which is seen on contrast material-enhanced CT scans, has been described in a variety of conditions. We tried to document that lymphatic obstruction is one of the major cause of periportal low attenuation. We retrospectively analyzed 57 cases of periportal low attenuation of abdominal CT scans and also reviewed the surgical records in 32 cases. Lymph node enlargement in the hepatoduodenal ligament which is a main lymphatic channel from the liver were analyzed the calculated the ratio of the transeverse diameter between the inferior vena cava and the aorta at the level of right adrenal gland. After complete surgical interruption of the lymphatic drainage from the liver in a dog, follow up CT scans were obtained and correlated with pathologic findings. Fifty patients (88%) had underlying disease which could cause impairment of lymphatic drainage. Periportal low attenuation was identified in several clinical conditions, including surgical lymph node dissection, lymphadenopathy in the hepatoduodenal ligament, blunt trauma. In animal model, CT scan showed prominent periportal low attenuation at 5 days after surgery. Histologic examination revealed numerous dilated lymphatic vessels and a marked lymphedema in the connective tissues surrounding the portal vein and its major branches. One of the major cause of periportal low attenuation was impaired lymphatic drainage and periportal low attenuation corresponding to the numerous dilated lymphatic vessels and a marked lymphedema in the connective tissues surrounding the portal vein and its major branches.

  2. A Precision Variable, Double Prism Attenuator for CO(2) Lasers. (United States)

    Oseki, T; Saito, S


    A precision, double prism attenuator for CO(2) lasers, calibrated by its gap capacitance, was constructed to evaluate its possible use as a standard for attenuation measurements. It was found that the accuracy was about 0.1 dB with a dynamic range of about 40 dB.

  3. Effect of lead attenuators on dose in homogeneous phantoms

    Energy Technology Data Exchange (ETDEWEB)

    El-Khatib, E.E.; Podgorsak, E.B.; Pla, C.


    In radiotherapy, the radiation beam is sometimes shaped so as to deliver different doses to different organs or give a homogeneous dose to structures of different densities. This objective is achieved by the use of attenuating materials introduced into the beam. These attenuators alter the primary as well as the scattered radiation components of the beam. There is at present no accurate method of dose calculation for these situations. Most calculations are performed considering only the effect of the attenuators on the primary radiation beam and can produce large errors in dosimetry. In the present study, the broad beam attenuation is investigated in homogeneous phantoms for various radiation field sizes, photon beam energies, and depths in phantom. A calculational method taking account of primary as well as first scatter radiation is developed. This method predicts reasonably well the transmission through lead attenuators for the various experimental conditions investigated.


    Directory of Open Access Journals (Sweden)

    G. N. Ezeh


    Full Text Available Rain attenuation is a major challenge to microwave satellite communication especially at frequencies above 10 GHz, causing unavailability of signals most of the time. Rain attenuation predictions have become one of the vital considerations while setting up a satellite communication link. In this study, rain attenuation models, cumulative distribution curves and other analytical tools for successful prediction of rain attenuation are presented. A three year Rain rate data was obtained from the Nigeria Meteorological Agency (NIMET database in addition to experimental data. Of the three prediction models used in the study, Ajayi model gave the range of values closest to the experimental data. A correctional factor was determined as 1.0988 and used to modify the Ajayi model. This modification to Ajayi’s model enabled its rain attenuation values conform more closely to the experimental result.

  5. Molecular attenuation and phase dispersion between 40 and 140-GHz for path models from different altitudes (United States)

    Liebe, H. J.; Welch, W. M.


    Radio wave propagation in the 40 to 140 GHz band through the first hundred kilometers of the atmosphere is strongly influenced by the microwave spectrum of oxygen (O2-MS). A unified treatment of molecular attenuation and phase dispersion is formulated. Results of molecular physics are translated into frequency, temperature, pressure, and magnetic field dependencies of a complex refractive index. The intensity distribution of the O2-MS undergoes several changes with increasing altitude. The influence of water vapor is discussed. Examples of computer plots are given as a function of altitude for homogeneous, zenith, and tangential path geometries. Molecular resonances of minor atmospheric gases are discussed briefly.

  6. Doppler-shift attenuation method lifetime measurements of low-lying states in {sup 111}In

    Energy Technology Data Exchange (ETDEWEB)

    Bucurescu, D.; Cata-Danil, I.; Ilas, G.; Ivascu, M.; Marginean, N.; Stroe, L.; Ur, C.A. [Institute of Atomic Physics, P.O. Box MG-6, Bucharest 76900 (Romania)


    The lifetimes of nine low-lying excited states in {sup 111}In have been measured with the Doppler-shift attenuation method in the {sup 111}Cd({ital p},{ital n}{gamma}) reaction. A comparison of experimental quantities with predictions based on the interacting boson-fermion model unravels the states due to the coupling of a {ital g}{sub 9/2} proton hole to the quadrupole vibrations of the core. {copyright} {ital 1996 The American Physical Society.}

  7. Medical Physics


    Voto Bernales, Juan; Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú


    Medical Physics is to study the physical phenomena that occur in the body and exert action on the agents. It also addresses the manner taught natural agents in the study and exploration of the human body and in the way in the same agents for use in the treatment of disease can be used. La Física Médica tiene por objeto estudiar los fenómenos físicos que se realizan en el organismo y la acción que sobre el ejercen los agentes. Se ocupa, además, de enseñar la manera cómo pueden utilizarse lo...

  8. Nuclear Physics

    CERN Document Server

    Savage, Martin J


    Lattice QCD is making good progress toward calculating the structure and properties of light nuclei and the forces between nucleons. These calculations will ultimately refine the nuclear forces, particularly in the three- and four-nucleon sector and the short-distance interactions of nucleons with electroweak currents, and allow for a reduction of uncertainties in nuclear many-body calculations of nuclei and their reactions. After highlighting their importance, particularly to the Nuclear Physics and High-Energy Physics experimental programs, I discuss the progress that has been made toward achieving these goals and the challenges that remain.

  9. Molecular physics

    CERN Document Server

    Demtröder, Wolfgang


    The richly illustrated book comprehensively explains the important principles of diatomic and polyatomic molecules and their spectra in two separate, distinct parts. The first part concentrates on the theoretical aspects of molecular physics, such as the vibration, rotation, electronic states, potential curves, and spectra of molecules. The different methods of approximation for the calculation of electronic wave functions and their energy are also covered. The introduction of basics terms used in group theory and their meaning in molecular physics enables an elegant description of polyatomic

  10. Mathematical physics

    CERN Document Server

    Geroch, Robert


    Mathematical Physics is an introduction to such basic mathematical structures as groups, vector spaces, topological spaces, measure spaces, and Hilbert space. Geroch uses category theory to emphasize both the interrelationships among different structures and the unity of mathematics. Perhaps the most valuable feature of the book is the illuminating intuitive discussion of the ""whys"" of proofs and of axioms and definitions. This book, based on Geroch's University of Chicago course, will be especially helpful to those working in theoretical physics, including such areas as relativity, particle

  11. Seismic attenuation of the inner core: Viscoelastic or stratigraphic? (United States)

    Cormier, V.F.; Xu, L.; Choy, G.L.


    Broadband velocity waveforms of PKIKP in the distance range 150??to 180??are inverted for inner core attenuation. A mean Q?? of 244 is determined at 1 Hz from 8 polar and 9 equatorial paths. The scatter in measured Q-1 exceeds individual error estimates, suggesting significant variation in attenuation with path. These results are interpreted by (1) viscoelasticity, in which the relaxation spectrum has a low-frequency corner near or slightly above the frequency band of short-period body waves, and by (2) stratigraphic (scattering) attenuation, in which attenuation and pulse broadening are caused by the interference of scattered multiples in a velocity structure having rapid fluctuations along a PKIKP path. In the scattering interpretation, PKIKP attenuation is only weakly affected by the intrinsic shear attenuation measured in the free-oscillation band. Instead, its frequency dependence, path variations, and fluctuations are all explained by scattering attenuation in a heterogeneous fabric resulting from solidification texturing of intrinsically anisotropic iron. The requisite fabric may consist of either single or ordered groups of crystals with P velocity differences of at least 5% and as much as 12% between two crystallographic axes at scale lengths of 0.5 to 2 km in the direction parallel to the axis of rotation and longer in the cylindrically radial direction, perpendicular to the axis of rotation.Broadband velocity waveforms of PKIKP in the distance range 150?? to 180?? are inverted for inner core attenuation. A mean Q?? of 244 is determined at 1 Hz from 8 polar and 9 equatorial paths. The scatter in the measured Q-1 exceeds individual error estimates, indicating significant variation in attenuation with path. The results are interpreted by viscoelasticity and stratigraphic (scattering) attenuation.

  12. In Situ Bioremediation by Natural Attenuation: from Lab to Field Scale (United States)

    Banwart, S. A.; Thornton, S.; Rees, H.; Lerner, D.; Wilson, R.; Romero-Gonzalez, M.


    In Situ Bioremediation is a passive technology to degrade soil and groundwater contamination in order to reduce environmental and human health risk. Natural attenuation is the application of engineering biotechnology principles to soil and groundwater systems as natural bioreactors to transform or immobilize contamination to less toxic or less bioavailable forms. Current advances in computational methods and site investigation techniques now allow detailed numerical models to be adequately parameterized for interpretation of processes and their interactions in the complex sub-surface system. Clues about biodegradation processes point to the dominant but poorly understood behaviour of attached growth microbial populations that exist within the context of biofilm formation. New techniques that combine biological imaging with non-destructive chemical analysis are providing new insights into attached growth influence on Natural Attenuation. Laboratory studies have been carried out in porous media packed bed reactors that physically simulate plume formation in aquifers. Key results show that only a small percentage of the total biomass within the plume is metabolically active and that activity is greatest at the plume fringe. This increased activity coincides with the zone where dispersive mixing brings dissolved O2 from outside the plume in contact with the contamination and microbes. The exciting new experimental approaches in lab systems offer tremendous potential to move Natural Attenuation and other in situ bioremediation approaches away from purely empirical engineering approaches, to process descriptions that are far more strongly based on first principles and that have a far greater predictive capacity for remediation performance assessment.

  13. Imprint of the atmospheric attenuation process on electron distribution in EAS (United States)

    Dey, R. K.; Dam, S.; Ray, S.


    The lateral density distribution (LDD) of shower particles in an extensive air shower (EAS) experiment is commonly approximated by a particular type of lateral density function (LDF). A standard perception is being used in air shower physics since long, according to which the LDD is assumed to be symmetric about the EAS axis, and the adopted LDF is adequate for the description of the LDD. However, the simulated electron density of a non-vertical EAS is asymmetric. In this work, such asymmetry in the LDD can be qualitatively explained as the atmospheric attenuation suffered by each shower particle. Quantitatively, the asymmetry can be roughly described in terms of a gap length (GL) between the EAS core and the center of the modified density pattern consisting of several equi-density ellipses. This study also validates the use of such a modeling of the atmospheric attenuation on the electromagnetic component in an EAS by investigating the so called GL in simulated density data. A modified LDF is proposed, based on these features of the simulated densities for the purpose of shower reconstruction in EAS experiments. The GL arises from attenuation effect is found to increase with the mass of the shower initiating particle. A different radial dependence of the local age parameter (LAP) is seen, if the modified LDF is applied to simulated electron densities. Primary cosmic-ray mass sensitivity of the LAP is also re-examined.

  14. Separating the effects of intrinsic and scattering seismic attenuation in Southern Taiwan (United States)

    Chi, Tsung-Chih; Ou, Gwo-Bin; Huang, Bor-Shouh


    During seismic waves propagate in the medium, the energy will disperse because of geological complexity. In general, the traveling energy can be involved in the conversion of elastic energy to anelastic processes (intrinsic absorption) and the scattering from heterogeneities (scattering attenuation) in the lithosphere. Shown in seismic waves at high frequencies degree of coda content will display the geological structure characteristics in the region. To estimate the energy redistribution in the propagation pool is an important problem in seismology and in engineering. In this study, we use the energy flux model developed by Frankel and Wennerberg (1987) to separate the effects of intrinsic and scattering attenuation. The analyzed seismic coda waves begin at least twice the direct S-wave travel time form the local events recorded by the Taiwan Strong Motion Network in southern Taiwan. The data are filted with center frequencies at 1.0 Hz, 3.0 Hz, 5.0 Hz and 10.0 Hz by using the Butterworth filter. We hope the result can help us better understand the physical mechanisms of seismic attenuation in the lithosphere and explain the high-frequency seismograms.

  15. Imprint of the atmospheric attenuation process on electron distribution in EAS (United States)

    Dey, R. K.; Dam, S.; Ray, S.


    The lateral density distribution (LDD) of shower particles in an extensive air shower (EAS) experiment is commonly approximated by a particular type of lateral density function (LDF). A standard perception is being used in air shower physics since long, according to which the LDD is assumed to be symmetric about the EAS axis, and the adopted LDF is adequate for the description of the LDD. However, the simulated electron density of a non-vertical EAS is asymmetric. In this work, such asymmetry in the LDD can be qualitatively explained as the atmospheric attenuation suffered by each shower particle. Quantitatively, the asymmetry can be roughly described in terms of a gap length (GL) between the EAS core and the center of the modified density pattern consisting of several equi-density ellipses. This study also validates the use of such a modeling of the atmospheric attenuation on the electromagnetic component in an EAS by investigating the so called GL in simulated density data. A modified LDF is proposed, based on these features of the simulated densities for the purpose of shower reconstruction in EAS experiments. The GL arises from attenuation effect is found to increase with the mass of the shower initiating particle. A different radial dependence of the local age parameter (LAP) is seen, if the modified LDF is applied to simulated electron densities. Primary cosmic-ray mass sensitivity of the LAP is also re-examined.

  16. Complex systems: physics beyond physics (United States)

    Holovatch, Yurij; Kenna, Ralph; Thurner, Stefan


    Complex systems are characterised by specific time-dependent interactions among their many constituents. As a consequence they often manifest rich, non-trivial and unexpected behaviour. Examples arise both in the physical and non-physical worlds. The study of complex systems forms a new interdisciplinary research area that cuts across physics, biology, ecology, economics, sociology, and the humanities. In this paper we review the essence of complex systems from a physicists' point of view, and try to clarify what makes them conceptually different from systems that are traditionally studied in physics. Our goal is to demonstrate how the dynamics of such systems may be conceptualised in quantitative and predictive terms by extending notions from statistical physics and how they can often be captured in a framework of co-evolving multiplex network structures. We mention three areas of complex-systems science that are currently studied extensively, the science of cities, dynamics of societies, and the representation of texts as evolutionary objects. We discuss why these areas form complex systems in the above sense. We argue that there exists plenty of new ground for physicists to explore and that methodical and conceptual progress is needed most.

  17. Flipped Physics (United States)

    Kettle, Maria


    This paper defines flipped learning and then examines its practical implementation in AS and A2 level physics classes, that is, classes for 16-18 year olds. The effect of this teaching style on student learning behaviour and its impact on test results are evaluated. The paper recounts the difficulties of implementing it and evaluates student…

  18. Atomic physics

    CERN Document Server

    Born, Max


    The Nobel Laureate's brilliant exposition of the kinetic theory of gases, elementary particles, the nuclear atom, wave-corpuscles, atomic structure and spectral lines, electron spin and Pauli's principle, quantum statistics, molecular structure and nuclear physics. Over 40 appendices, a bibliography, numerous figures and graphs.

  19. Unifying Physics (United States)

    Goradia, Shantilal


    Century old GR fails to unify quantum physics, nuclear force or distinguish between the mass of living bodies from inert mass. Probabilistic gravity [1] explains strong coupling (nuclear force). The natural log of the age of the universe, 10E60 in Planck times, equaling 137 (1/Alpha) extends physics to deeper science, if we stand on the shoulders of giants like Feynman and Gamow. Implications of [1] are that it is not the earth, but M and S numbers of the particles of the earth are remotely interacting with corresponding numbers of the particles of the moon and the sun respectively, neglecting other heavenly bodies in this short draft. This new physics is likely to enable creative scientific minds to throw light on a theoretical basis for an otherwise arbitrary cosmological constant, uniformity of microwave background, further vindication of Boltzmann, quantum informatics, Einstein’s later publicized views and more, eliminating the need to spend money for implicitly nonexistent quantum gravity and graviton.[4pt] [1] Journal of Physical Science and Applications 2 (7) (2012) 265-268.

  20. Physics Portfolios (United States)

    Whitworth, Brooke A.; Bell, Randy L.


    Traditionally, teachers assess students' physics understanding through lab activities, responses to open-ended word problems, and tests. But there is another way to measure student understanding, one in which students apply their learning to the world around them. This article shows how to implement student portfolios, which allow students to…

  1. Physical Linguistics. (United States)

    Tice, Bradley S.

    Physical linguistics is defined as the use of treatments from the field of speech pathology to enhance first and second language production in healthy individuals, resulting in increased quality and strength of phonation and articulation. A series of exercises for treating dysarthria (weakness, paralysis, discoordination, primary and secondary…

  2. Physics News

    CERN Multimedia

    Gianotti, F.

    In spite of the fact that real data will only come in the year 2006, this is a very busy and interesting time for Physics-related activities. A very short overview of these activities is given in this issue of the ATLAS News Letter, while the various topics will be described in more detail in the next issues. The Physics and Combined Performance groups are working in four main areas: 1) Assess the ATLAS potential for physics, with emphasis on new channels and ideas. Recent examples are Extra-dimensions, invisible Higgs decays, heavy ion physics, the expected potential of a "Super-LHC" running at a luminosity of 10^35, etc.. 2) Improve the understanding of the detector performance and optimise the reconstruction algorithms. Examples of issues in the pipeline are: can we tag charm-jet ? What can we gain in the jet energy resolution by combining the calorimeter and tracker information to reconstruct the jet energy ? 3) Follow detector changes and detector-related issues and monitor the impact on the perform...

  3. RHIC physics

    CERN Document Server

    Pajares, C


    A brief review of the hadronic phase transitions is presented by emphasizing the physical ideas and the main signatures of the transition in relation to the most significant results of the SPS experiments and the description of the RHIC experiments. (77 refs).

  4. Fundamental Physics

    CERN Document Server

    Ydri, Badis


    This book includes my lectures, together with their problem sets and solutions, on 1) classical mechanics (one semester), 2) thermodynamics and statistical mechanics (one semester), and 3) quantum mechanics (one semester), which I have been giving to graduate students of theoretical physics at Annaba University since 2010 .

  5. Cardiovascular Reactivity, Stress, and Physical Activity

    Directory of Open Access Journals (Sweden)

    Chun-Jung eHuang


    Full Text Available Psychological stress has been proposed as a major contributor to the progression of cardiovascular disease (CVD. Acute mental stress can activate the sympathetic-adrenal-medullary (SAM axis, eliciting the release of catecholamines (NE and EPI resulting in the elevation of heart rate (HR and blood pressure (BP. Combined stress (psychological and physical can exacerbate these cardiovascular responses, which may partially contribute to the elevated risk of CVD and increased proportionate mortality risks experienced by some occupations (e.g., firefighting and law enforcement. Studies have supported the benefits of physical activity on physiological and psychological health, including the cardiovascular response to acute stress. Aerobically trained individuals exhibit lower sympathetic nervous system (e.g., HR reactivity and enhanced cardiovascular efficiency (e.g., lower vascular reactivity and decreased recovery time in response to physical and/or psychological stress. In addition, resistance training has been demonstrated to attenuate cardiovascular responses and improve mental health. This review will examine stress-induced cardiovascular reactivity and plausible explanations for how exercise training and physical fitness (aerobic and resistance exercise can attenuate cardiovascular responses to stress. This enhanced functionality may facilitate a reduction in the incidence of stroke and myocardial infarction. Finally, this review will also address the interaction of obesity and physical activity on cardiovascular reactivity and CVD.

  6. Finite-difference numerical modelling of gravito-acoustic wave propagation in a windy and attenuating atmosphere



    in press; International audience; Acoustic and gravity waves propagating in planetary atmospheres have been studied intensively as markers of specific phenomena such as tectonic events or explosions or as contributors to atmosphere dynamics. To get a better understanding of the physics behind these dynamic processes, both acoustic and gravity waves propagation should be modelled in a 3D attenuating and windy atmosphere extending from the ground to the upper thermosphere. Thus, in order to pro...

  7. Phosphatidylserine and caffeine attenuate postexercise mood disturbance and perception of fatigue in humans. (United States)

    Wells, Adam J; Hoffman, Jay R; Gonzalez, Adam M; Stout, Jeffrey R; Fragala, Maren S; Mangine, Gerald T; McCormack, William P; Jajtner, Adam R; Townsend, Jeremy R; Robinson, Edward H


    Phosphatidylserine (PS) may attenuate the adverse effects of physical fatigue. Therefore, we investigated the effects of a multi-ingredient supplement containing 400 mg/d PS and 100 mg/d caffeine (supplement [SUP]) for 2 weeks on measures of cognitive function (CF), reaction time (RT), and mood (MD) following an acute exercise stress. It is hypothesized that PS will maintain preexercise CF and RT scores, while attenuating postexercise fatigue. Participants completed 2 acute bouts of resistance exercise (T1 and T2) separated by 2-week ingestion of SUP or control (CON). Outcome measures were assessed pre- and postexercise. When collapsed across groups, a significant decrease in RT performance was seen in the 60-second reaction drill from pre- to postexercise at T1. All other RT tests were similar from pre- to postexercise at T1. Reaction time was not significantly changed by PS. When collapsed across groups, a significant increase in performance of the serial subtraction test was seen. A significant increase (8.9% and 7.1%) in the number of correct answers and a significant decrease (8.0% and 7.5%) in time to answer were seen from pre- to postworkout at T1 and T2, respectively. A significant increase in total MD score from pre- to postworkout was observed for CON but not for PS at T2. Phosphatidylserine significantly attenuated pre- to postexercise perception of fatigue compared to CON. Ingestion of SUP for 14 days appears to attenuate postexercise MD scores and perception of fatigue, but does not affect CF or RT, in recreationally trained individuals.

  8. Evaluation of downwelling diffuse attenuation coefficient algorithms in the Red Sea

    KAUST Repository

    Tiwari, Surya Prakash


    Despite the importance of the optical properties such as the downwelling diffuse attenuation coefficient for characterizing the upper water column, until recently no in situ optical measurements were published for the Red Sea. Kirby et al. used observations from the Coastal Zone Color Scanner to characterize the spatial and temporal variability of the diffuse attenuation coefficient (Kd(490)) in the Red Sea. To better understand optical variability and its utility in the Red Sea, it is imperative to comprehend the diffuse attenuation coefficient and its relationship with in situ properties. Two apparent optical properties, spectral remote sensing reflectance (Rrs) and the downwelling diffuse attenuation coefficient (Kd), are calculated from vertical profile measurements of downwelling irradiance (Ed) and upwelling radiance (Lu). Kd characterizes light penetration into water column that is important for understanding both the physical and biogeochemical environment, including water quality and the health of ocean environment. Our study tests the performance of the existing Kd(490) algorithms in the Red Sea and compares them against direct in situ measurements within various subdivisions of the Red Sea. Most standard algorithms either overestimated or underestimated with the measured in situ values of Kd. Consequently, these algorithms provided poor retrieval of Kd(490) for the Red Sea. Random errors were high for all algorithms and the correlation coefficients (r2) with in situ measurements were quite low. Hence, these algorithms may not be suitable for the Red Sea. Overall, statistical analyses of the various algorithms indicated that the existing algorithms are inadequate for the Red Sea. The present study suggests that reparameterizing existing algorithms or developing new regional algorithms is required to improve retrieval of Kd(490) for the Red Sea. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is

  9. Radiation attenuation by lead and nonlead materials used in radiation shielding garments. (United States)

    McCaffrey, J P; Shen, H; Downton, B; Mainegra-Hing, E


    The attenuating properties of several types of lead (Pb)-based and non-Pb radiation shielding materials were studied and a correlation was made of radiation attenuation, materials properties, calculated spectra and ambient dose equivalent. Utilizing the well-characterized x-ray and gamma ray beams at the National Research Council of Canada, air kerma measurements were used to compare a variety of commercial and pre-commercial radiation shielding materials over mean energy ranges from 39 to 205 keV. The EGSnrc Monte Carlo user code cavity. cpp was extended to provide computed spectra for a variety of elements that have been used as a replacement for Pb in radiation shielding garments. Computed air kerma values were compared with experimental values and with the SRS-30 catalogue of diagnostic spectra available through the Institute of Physics and Engineering in Medicine Report 78. In addition to garment materials, measurements also included pure Pb sheets, allowing direct comparisons to the common industry standards of 0.25 and 0.5 mm "lead equivalent." The parameter "lead equivalent" is misleading, since photon attenuation properties for all materials (including Pb) vary significantly over the energy spectrum, with the largest variations occurring in the diagnostic imaging range. Furthermore, air kerma measurements are typically made to determine attenuation properties without reference to the measures of biological damage such as ambient dose equivalent, which also vary significantly with air kerma over the diagnostic imaging energy range. A single material or combination cannot provide optimum shielding for all energy ranges. However, appropriate choice of materials for a particular energy range can offer significantly improved shielding per unit mass over traditional Pb-based materials.

  10. Agmatine attenuates silica-induced pulmonary fibrosis. (United States)

    El-Agamy, D S; Sharawy, M H; Ammar, E M


    There is a large body of evidence that nitric oxide (NO) formation is implicated in mediating silica-induced pulmonary fibrosis. As a reactive free radical, NO may not only contribute to lung parenchymal tissue injury but also has the ability to combine with superoxide and form a highly reactive toxic species peroxynitrite that can induce extensive cellular toxicity in the lung tissues. This study aimed to explore the effect of agmatine, a known NO synthase inhibitor, on silica-induced pulmonary fibrosis in rats. Male Sprague Dawley rats were treated with agmatine for 60 days following a single intranasal instillation of silica suspension (50 mg in 0.1 ml saline/rat). The results revealed that agmatine attenuated silica-induced lung inflammation as it decreased the lung wet/dry weight ratio, protein concentration, and the accumulation of the inflammatory cells in the bronchoalveolar lavage fluid. Agmatine showed antifibrotic activity as it decreased total hydroxyproline content of the lung and reduced silica-mediated lung inflammation and fibrosis in lung histopathological specimen. In addition, agmatine significantly increased superoxide dismutase (p pulmonary nitrite/nitrate as well as tumor necrosis factor α. Collectively, these results demonstrate the protective effects of agmatine against the silica-induced lung fibrosis that may be attributed to its ability to counteract the NO production, lipid peroxidation, and regulate cytokine effects.

  11. Photoacoustic imaging taking into account thermodynamic attenuation (United States)

    Acosta, Sebastián; Montalto, Carlos


    In this paper we consider a mathematical model for photoacoustic imaging which takes into account attenuation due to thermodynamic dissipation. The propagation of acoustic (compressional) waves is governed by a scalar wave equation coupled to the heat equation for the excess temperature. We seek to recover the initial acoustic profile from knowledge of acoustic measurements at the boundary. We recognize that this inverse problem is a special case of boundary observability for a thermoelastic system. This leads to the use of control/observability tools to prove the unique and stable recovery of the initial acoustic profile in the weak thermoelastic coupling regime. This approach is constructive, yielding a solvable equation for the unknown acoustic profile. Moreover, the solution to this reconstruction equation can be approximated numerically using the conjugate gradient method. If certain geometrical conditions for the wave speed are satisfied, this approach is well-suited for variable media and for measurements on a subset of the boundary. We also present a numerical implementation of the proposed reconstruction algorithm.

  12. Ultrasonic attenuation in rare-earth monoarsenides

    Indian Academy of Sciences (India)



    The present paper deals with the theoretical calculation of mechanical and thermophysical properties of rare-earth monoarsenides, XAs (X: Np, Pu, Th and U) using elastic constants as the input parameters. These second- and third-order elastic constants (SOECs and TOECs) are determinedin the temperature range 100–500K using Coulomb and Born–Mayer potential upto second nearest neighbours. In order to provide the link between mechanical and dynamical behaviour of crystals, parameters such as Young’s modulus, bulk modulus, Poisson’s ratio etc. are also calculated.In addition, the Cauchy relationship is obeyed by the chosen monoarsenides and are fairly anisotropic, which results in the measurement of longitudinal and shear wave velocities along $\\langle100 \\rangle$, $\\langle110\\rangle$ and $\\langle 111\\rangle$ directions. The toughness/fracture $(G/BT)$ ratio is greater than 0.60, which implies that XAs compounds are brittle at room temperature. Further, the Debye temperature is computed using Debye average velocity as the input parameter. It helps in the characterization of lattice vibrations of a solid. In this work, ultrasonic attenuation due to phonon–phonon interaction$\\alpha/f^2_{\\rm p−p}$ and thermoelastic loss $\\alpha/f ^{2}$th are computed for XAs from 100 to 500K using Mason’s theory. It further helps in evaluating the microstructural properties of the chosen materials. The obtained results indicate that XAs is mechanically stable and are compared with data availablein the literature.

  13. Statins attenuate polymethylmethacrylate-mediated monocyte activation.

    LENUS (Irish Health Repository)

    Laing, Alan J


    BACKGROUND: Periprosthetic osteolysis precipitates aseptic loosening of components, increases the risk of periprosthetic fracture and, through massive bone loss, complicates revision surgery and ultimately is the primary cause for failure of joint arthroplasty. The anti-inflammatory properties of HMG-CoA reductase inhibitors belonging to the statin family are well recognized. We investigated a possible role for status in initiating the first stage of the osteolytic cycle, namely monocytic activation. METHODS: We used an in vitro model of the human monocyte\\/macrophage inflammatory response to poly-methylmethacrylate (PMMA) particles after pretreat-ing cells with cerivastatin, a potent member of the statin family. Cell activation based upon production of TNF-alpha and MCP-1 cytokines was analyzed and the intracellular Raf-MEK-ERK signal transduction pathway was evaluated using western blot analysis, to identify its role in cell activation and in any cerivastatin effects observed. RESULTS: We found that pretreatment with cerivastatin significantly abrogates the production of inflammatory cytokines TNF-alpha and MCP-1 by human monocytes in response to polymethylmethacrylate particle activation. This inflammatory activation and attenuation appear to be mediated through the intracellular Raf-MEK-ERK pathway. INTERPRETATION: We propose that by intervening at the upstream activation stage, subsequent osteoclast activation and osteolysis can be suppressed. We believe that the anti-inflammatory properties of statins may potentially play a prophylactic role in the setting of aseptic loosening, and in so doing increase implant longevity.

  14. Atorvastatin attenuates oxidative stress in Alzheimer's disease

    Institute of Scientific and Technical Information of China (English)

    Cai Zhiyou; Yan Yong; Wang Yonglong


    Objective: To investigate serum level of SOD, MDA, ox-LDL, AchE and Ach in AD, to study atorvastatin influence on serum level of SOD, MDA, ox-LDL, AchE and Acb in AD and its neuroprotection mechanisms. Methods Subjects were divided into: normal blood lipid level group with Alzheimer's disease (A), higher blood lipid level group with Alzheimer's disease (AH), normal blood lipid level Alzheimer's disease group with atorvastatin treeatment (AT),higher blood lipid level Alzheimer's disease group with atorvastatin treeatment(AHT). Ox-LDL was measured by enzyme linked immunosorbent assay; SOD, MDA, ox-LDL, AchE, Ach and blood lipid level in AD was measured by biochemistry. Results: The serum level of MDA, AchE in AH group after atorvastatin treatment is lower ;The serum level of SOD, Ach in AH group is more increased than that of in A group; The serum level of ox-LDL in AH, A groups is lower than that of in A group; The dementia degree is lower after atorvastatin treatment. Conclusion: Atorvastatin can decrease serum level of MDA, AchE and ox-LDL, and increase that of SOD, Acb, and attenuate dementia symptom in AD, especially, with hyperlipemia. The hypothesis of atorvastatin neuroprotection is concluded that atorvastatin may restrain free radical reaction and retard oxidation in AD.

  15. Silibinin attenuates allergic airway inflammation in mice

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yun Ho [Department of Anatomy, Medical School, Institute for Medical Sciences, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Jin, Guang Yu [Department of Radiology, Yanbian University Hospital, YanJi 133002 (China); Guo, Hui Shu [Centralab, The First Affiliated Hospital of Dalian Medical University, Dalian 116011 (China); Piao, Hong Mei [Department of Respiratory Medicine, Yanbian University Hospital, YanJi 133000 (China); Li, Liang chang; Li, Guang Zhao [Department of Anatomy and Histology and Embryology, Yanbian University School of Basic Medical Sciences, 977 Gongyuan Road, YanJi 133002, Jilin (China); Lin, Zhen Hua [Department of Pathology, Yanbian University School of Basic Medical Sciences, YanJi 133000 (China); Yan, Guang Hai, E-mail: [Department of Anatomy and Histology and Embryology, Yanbian University School of Basic Medical Sciences, 977 Gongyuan Road, YanJi 133002, Jilin (China)


    Highlights: Black-Right-Pointing-Pointer Silibinin diminishes ovalbumin-induced inflammatory reactions in the mouse lung. Black-Right-Pointing-Pointer Silibinin reduces the levels of various cytokines into the lung of allergic mice. Black-Right-Pointing-Pointer Silibinin prevents the development of airway hyperresponsiveness in allergic mice. Black-Right-Pointing-Pointer Silibinin suppresses NF-{kappa}B transcriptional activity. -- Abstract: Allergic asthma is a chronic inflammatory disease regulated by coordination of T-helper2 (Th2) type cytokines and inflammatory signal molecules. Silibinin is one of the main flavonoids produced by milk thistle, which is reported to inhibit the inflammatory response by suppressing the nuclear factor-kappa B (NF-{kappa}B) pathway. Because NF-{kappa}B activation plays a pivotal role in the pathogenesis of allergic inflammation, we have investigated the effect of silibinin on a mouse ovalbumin (OVA)-induced asthma model. Airway hyperresponsiveness, cytokines levels, and eosinophilic infiltration were analyzed in bronchoalveolar lavage fluid and lung tissue. Pretreatment of silibinin significantly inhibited airway inflammatory cell recruitment and peribronchiolar inflammation and reduced the production of various cytokines in bronchoalveolar fluid. In addition, silibinin prevented the development of airway hyperresponsiveness and attenuated the OVA challenge-induced NF-{kappa}B activation. These findings indicate that silibinin protects against OVA-induced airway inflammation, at least in part via downregulation of NF-{kappa}B activity. Our data support the utility of silibinin as a potential medicine for the treatment of asthma.

  16. A prototype piecewise-linear dynamic attenuator (United States)

    Hsieh, Scott S.; Peng, Mark V.; May, Christopher A.; Shunhavanich, Picha; Fleischmann, Dominik; Pelc, Norbert J.


    The piecewise-linear dynamic attenuator has been proposed as a mechanism in CT scanning for personalizing the x-ray illumination on a patient- and application-specific basis. Previous simulations have shown benefits in image quality, scatter, and dose objectives. We report on the first prototype implementation. This prototype is reduced in scale and speed and is integrated into a tabletop CT system with a smaller field of view (25 cm) and longer scan time (42 s) compared to a clinical system. Stainless steel wedges were machined and affixed to linear actuators, which were in turn held secure by a frame built using rapid prototyping technologies. The actuators were computer-controlled, with characteristic noise of about 100 microns. Simulations suggest that in a clinical setting, the impact of actuator noise could lead to artifacts of only 1 HU. Ring artifacts were minimized by careful design of the wedges. A water beam hardening correction was applied and the scan was collimated to reduce scatter. We scanned a 16 cm water cylinder phantom as well as an anthropomorphic pediatric phantom. The artifacts present in reconstructed images are comparable to artifacts normally seen with this tabletop system. Compared to a flat-field reference scan, increased detectability at reduced dose is shown and streaking is reduced. Artifacts are modest in our images and further refinement is possible. Issues of mechanical speed and stability in the challenging clinical CT environment will be addressed in a future design.

  17. EDITORIAL: Physics competitions Physics competitions (United States)

    Jordens, H.; Mathelitsch, L.


    1. Physics competitions: aims and realizations One aim of physics competitions is to increase the interest of young students, primarily at upper secondary level, to physics and natural sciences in general. A competition has motivational aspects known usually from sports events or games—comparing one's own ability with others, of course with the desire to be better and to win. If competitions reach nationwide and even international levels, additional stimulation is created. Competitions provide greatest attraction to possible winners, to the group of gifted people in a particular field. This implies that science contests are excellent tools for the promotion of talented students. Traditional teaching has been shown to have problems in supporting this group of students. Very often teachers are overstretched with the demands of teaching both low- and high-level students. Extracurricular activities are therefore a good chance to relieve the teacher, and to give talented students the opportunity for appropriate training and challenge. The competitions, however, have a broader impact and address more young people than one might guess from the statements above. Training courses and selection at school level give a larger group of students extra and, to some extent, complimentary education in physics. The degree of complexity of the tasks corresponds very often to the standards of the next level of education in the school system. Interestingly, many physics competitions have their origin in countries beyond the former Iron Curtain. They started as regional and national tournaments, were joined by neighbouring countries and have grown, in some cases, to events with participants from more than 80 countries. Although the features mentioned above are common to the different competitions, there are distinct differences between them [1]. The International Physics Olympiad (IPhO) is the oldest international physics competition for students at upper secondary level [2]. It dates

  18. Broadband Lg Attenuation Modeling in the Middle East

    Energy Technology Data Exchange (ETDEWEB)

    Pasyanos, M E; Matzel, E M; Walter, W R; Rodgers, A J


    We present a broadband tomographic model of Lg attenuation in the Middle East derived from source- and site-corrected amplitudes. Absolute amplitude measurements are made on hand-selected and carefully windowed seismograms for tens of stations and thousands of crustal earthquakes resulting in excellent coverage of the region. A conjugate gradient method is used to tomographically invert the amplitude dataset of over 8000 paths over a 45{sup o} x 40{sup o} region of the Middle East. We solve for Q variation, as well as site and source terms, for a wide range of frequencies ranging from 0.5-10 Hz. We have modified the standard attenuation tomography technique to more explicitly define the earthquake source expression in terms of the seismic moment. This facilitates the use of the model to predict the expected amplitudes of new events, an important consideration for earthquake hazard or explosion monitoring applications. The attenuation results have a strong correlation to tectonics. Shields have low attenuation, while tectonic regions have high attenuation, with the highest attenuation at 1 Hz is found in eastern Turkey. The results also compare favorably to other studies in the region made using Lg propagation efficiency, Lg/Pg amplitude ratios and two-station methods. We tomographically invert the amplitude measurements for each frequency independently. In doing so, it appears the frequency-dependence of attenuation is not compatible with the power law representation of Q(f), an assumption that is often made.

  19. Rain Attenuation Prediction for Terrestrial Microwave Link in Bangladesh

    Directory of Open Access Journals (Sweden)

    HOSSAIN Sakir


    Full Text Available Rain attenuation is a major shortcoming of microwave transmission. As a subtropical country, Bangladesh is one of the highest rainy areas of the world. Thus, designing a terrestrial microwave link is a serious challenge to the engineers. In this paper, the annual rain rate and monthly variation of rate are predicted for different percentage of time of the year from the measured rainfall data. Using ITU rain model for terrestrial microwave communication, the rain attenuation is predicted for five major cities of Bangladesh, namely Dhaka, Chittagong, Rajshahi, Sylhet, and Khulna. It is found that rain attenuation is the most severe in Sylhet and least in Rajshahi. The attenuation is estimated for different frequency and polarization. A horizontally polarized signal encounters 15% more rain attenuation than that of vertically polarized signal. It is also found that attenuation in Rajshahi is about 20% lesser than that in Sylhet. Thus, the horizontally polarized transmission in Rajshahi experiences about 5% less attenuation than the vertically polarized transmission in Sylhet.

  20. Assessment of mild steel damage characteristics by physical methods (United States)

    Botvina, L. R.; Soldatenkov, A. P.; Levin, V. P.; Tyutin, M. R.; Demina, Yu. A.; Petersen, T. B.; Dubov, A. A.; Semashko, N. A.


    The deformation and fracture localization characteristics are estimated by the methods of replicas, acoustic emission, metal magnetic memory, ultrasonic attenuation, microhardness, and electrical resistance. The relation between the estimated physical parameters on the one hand and the plastic zone size and the microcrack concentration in this zone, on the other, is considered.

  1. Molecular basis of live-attenuated influenza virus.

    Directory of Open Access Journals (Sweden)

    Wen He

    Full Text Available Human influenza is a seasonal disease associated with significant morbidity and mortality. The most effective means for controlling infection and thereby reducing morbidity and mortality is vaccination with a three inactivated influenza virus strains mixture, or by intranasal administration of a group of three different live attenuated influenza vaccine strains. Comparing to the inactivated vaccine, the attenuated live viruses allow better elicitation of a long-lasting and broader immune (humoral and cellular response that represents a naturally occurring transient infection. The cold-adapted (ca influenza A/AA/6/60 (H2N2 (AA ca virus is the backbone for the live attenuated trivalent seasonal influenza vaccine licensed in the United States. Similarly, the influenza A components of live-attenuated vaccines used in Russia have been prepared as reassortants of the cold-adapted (ca H2N2 viruses, A/Leningrad/134/17/57-ca (Len/17 and A/Leningrad/134/47/57-ca (Len/47 along with virulent epidemic strains. However, the mechanism of temperature-sensitive attenuation is largely elusive. To understand how modification at genetic level of influenza virus would result in attenuation of human influenza virus A/PR/8/34 (H1N1,A/PR8, we investigated the involvement of key mutations in the PB1 and/or PB2 genes in attenuation of influenza virus in vitro and in vivo. We have demonstrated that a few of residues in PB1 and PB2 are critical for the phenotypes of live attenuated, temperature sensitive influenza viruses by minigenome assay and real-time PCR. The information of these mutation loci could be used for elucidation of mechanism of temperature-sensitive attenuation and as a new strategy for influenza vaccine development.

  2. Rain attenuation statistics over millimeter wave bands in South Korea (United States)

    Shrestha, Sujan; Choi, Dong-You


    Rain induced degradations are significant for terrestrial microwave links operating at frequencies higher than 10 GHz. Paper presents analyses done on rain attenuation and rainfall data for three years between 2013 till 2015, in 3.2 km experimental link of 38 GHz and 0.1 km link at 75 GHz. The less link distance is maintained for 75 GHz operating frequency in order to have better recording of propagation effect as such attenuation induced by rain. OTT Parsivel is used for collection of rain rate database which show rain rate of about 50 mm/h and attenuation values of 20.89 and 28.55 dB are obtained at 0.01% of the time for vertical polarization under 38 and 75 GHz respectively. Prediction models, namely, ITU-R P. 530-16, Da Silva Mello, Moupfouma, Abdulrahman, Lin and differential equation approach are analyzed. This studies help to identify most suitable rain attenuation model for higher microwave bands. While applying ITU-R P. 530-16, the relative error margin of about 3%, 38% and 42% along with 80, 70, 61% were obtained in 0.1%, 0.01% and 0.001% of the time for vertical polarization under 38 and 75 GHz respectively. Interestingly, ITU-R P. 530-16 shows relatively closer estimation to measured rain attenuation at 75 GHz with relatively less error probabilities and additionally, Abdulrahman and ITU-R P. 530-16 results in better estimation to the measured rain attenuation at 38 GHz link. The performance of prominent rain attenuation models are judged with different error matrices as recommended by ITU-R P. 311-15. Furthermore, the efficacy of frequency scaling technique of rain attenuation between links distribution are also discussed. This study shall be useful for making good considerations in rain attenuation predictions for terrestrial link operating at higher frequencies.

  3. Frequency scaling of slant-path atmospheric attenuation in the absence of rain for millimeter-wave links (United States)

    Lucas-Vegas, María. José; Riera, José Manuel


    Broadband satellite communications systems, either used for broadcast or fixed satellite services, have grown continuously in recent years. This has led to the use of higher frequency bands, from the Ku (14/11 GHz) to the Ka band (30/20 GHz) in the last decade, and with the expectation of using the Q/V band (50/40 GHz) and even the W band (75-110 GHz) in the future. As frequency increases, radio wave propagation effects in the slant-path within the troposphere are becoming more and more relevant. The objective of this research is the proposal of frequency scaling approximations for the total attenuation in the absence of rain, a condition that occurs during the highest percentages of time, usually more than 95% in temperate climates. There is a strong relationship between total attenuation at different frequencies, as it arises from the same physical phenomena, namely, the presence of oxygen, water vapor, and clouds in the slant path. This strong relationship allows frequency scaling estimations to be proposed. In particular, polynomials for instantaneous frequency scaling of total attenuation under these conditions have been calculated for a set of frequencies in the range 10-100 GHz, based on atmospheric profiles of 60 sites from all over the world and physical models of attenuation. Global polynomials are provided for the 72 combinations of nine significant frequencies, which can be used to estimate attenuation at a frequency band from its known value at a different one. Refined expressions have also been calculated for different climatic zones, providing more precise estimations.

  4. EDITORIAL: Physics competitions Physics competitions (United States)

    Jordens, H.; Mathelitsch, L.


    International tests on competences, such as TIMSS or PISA, and knowledge of young students have revealed low average scores in many countries, often unexpectedly. One effective measure to increase the average standard of a population is to bring the last third of the group to a higher level. Therefore, many nations put some effort into this activity. This brings the danger that not enough attention is paid to students at the other end, those who are talented. Indeed, it is a very difficult task for a teacher to support the less able and at the same time challenge the gifted students, to lead them to the limits of their abilities and provide for a smooth transition to university study. Physics competitions have been proven to fulfil these last demands to a large degree, and therefore are an important additional and, to some extent, complementary tool for the promotion of talented students. This third special section on physics competitions in European Journal of Physics contains three papers, each dealing with a different form of science contest. The first continues the series of presentations of tasks performed at the International Young Physicists' Tournament, which was held in Vienna in 2011. First place went to the team from Singapore, and they have put their investigation on vertical oscillations of coupled magnets into written form (not required by the tournament, where an oral presentation and a defence and discussion are the central aspects). Their paper shows how rich in physics this problem is, and what level of solutions high-school students can already achieve. Sadly, those responsible for the organization of last year's International Physics Olympiad did not provide us with a report on this competition. This is unfortunate, since the Olympiad in Zagreb was very successful and, in particular, the experimental tasks were creative and demanding. Very similar to the aims and the execution of the Physics Olympiad is the International Olympiad on Astronomy

  5. Particle physics

    CERN Document Server

    Kennedy, Eugene


    Stimulated by the Large Hadron Collider and the search for the elusive Higgs Boson, interest in particle physics continues at a high level among scientists and the general public. This book includes theoretical aspects, with chapters outlining the generation model and a charged Higgs boson model as alternative scenarios to the Standard Model. An introduction is provided to postulated axion photon interactions and associated photon dispersion in magnetized media. The complexity of particle physics research requiring the synergistic combination of theory, hardware and computation is described in terms of the e-science paradigm. The book concludes with a chapter tackling potential radiation hazards associated with extremely weakly interacting neutrinos if produced in copious amounts with future high-energy muon-collider facilities.

  6. Reactor Physics

    Energy Technology Data Exchange (ETDEWEB)

    Ait Abderrahim, A


    The Reactor Physics and MYRRHA Department of SCK-CEN offers expertise in various areas of reactor physics, in particular in neutronics calculations, reactor dosimetry, reactor operation, reactor safety and control and non-destructive analysis of reactor fuel. This expertise is applied in the Department's own research projects in the VENUS critical facility, in the BR1 reactor and in the MYRRHA project (this project aims at designing a prototype Accelerator Driven System). Available expertise is also used in programmes external to the Department such as the reactor pressure steel vessel programme, the BR2 reactor dosimetry, and the preparation and interpretation of irradiation experiments by means of neutron and gamma calculations. The activities of the Fuzzy Logic and Intelligent Technologies in Nuclear Science programme cover several domains outside the department. Progress and achievements in these topical areas in 2000 are summarised.

  7. Astroparticle physics (United States)

    Ong, Rene A.


    Astroparticle physics is a rapidly developing field that has a high degree of overlap with particle physics and astronomy. This paper summarizes recent results and leading experiments in two selected areas: very high energy astrophysics and dark matter. Both areas have made great progress in the last 5 years due to improved instrumentation and a growing community. In very high energy astrophysics, many sources of GeV and TeV radiation have been detected and the challenge now is to fully understand the processes involved at these sites of extreme particle acceleration. In the area of dark matter, there is a close scientific connection between astroparticle experiments and the Large Hadron Collider (LHC). The combination of the LHC, direct-detection and indirect-detection experiments provide critical complementarity and unprecedented sensitivity in the quest to understand this deep mystery.

  8. Mastering physics

    CERN Multimedia


    CERN hosts a series of videoconference masterclasses for high-school students. A screen shot of part of the masterclasses videoconference. For two weeks in the middle of March CERN played host to a series of videoconferences as part of the European Particle Physics Masterclasses 2006. The masterclasses were organized for the second consecutive year by ATLAS physicist Michael Kobel from the Technical University of Dresden and colleagues from the European Particle Physics Outreach Group (EPPOG), and more than 3100 high-school students from the United States and 17 countries in Europe participated. On each of the 14 days, between four and six universities hosted groups of students, providing introductory lectures, institute tours and hands-on exercises including the popular 'Hands on CERN' package for analyzing LEP data. To support these events, a CD containing material in 16 languages was distributed to every student. As a grand finale of the day, the groups of students connected to CERN for a videoconference,...

  9. Terahertz physics

    CERN Document Server

    Lewis, R A


    Terahertz physics covers one of the least explored but richest regions of the electromagnetic spectrum. Designed for independent learning, this is the first book to open up this exciting new field to students of science and engineering. Written in a clear and consistent style, the textbook focuses on an understanding of fundamental physical principles at terahertz frequencies and their applications. Part I outlines the foundations of terahertz science, starting with the mathematical representation of oscillations before exploring terahertz-frequency light, terahertz phenomena in matter and the terahertz interactions between light and matter. Part II covers components of terahertz technology, from sources of terahertz frequency radiation, through the manipulation of the radiation, to its detection. Part III deals with applications, including time-domain spectroscopy. Highlighting modern developments and concepts, the book is ideal for self-study. It features precise definitions, clear explanations, instructive...

  10. Wave attenuation in the shallows of San Francisco Bay (United States)

    Lacy, Jessica R.; MacVean, Lissa J.


    Waves propagating over broad, gently-sloped shallows decrease in height due to frictional dissipation at the bed. We quantified wave-height evolution across 7 km of mudflat in San Pablo Bay (northern San Francisco Bay), an environment where tidal mixing prevents the formation of fluid mud. Wave height was measured along a cross shore transect (elevation range−2mto+0.45mMLLW) in winter 2011 and summer 2012. Wave height decreased more than 50% across the transect. The exponential decay coefficient λ was inversely related to depth squared (λ=6×10−4h−2). The physical roughness length scale kb, estimated from near-bed turbulence measurements, was 3.5×10−3 m in winter and 1.1×10−2 m in summer. Estimated wave friction factor fw determined from wave-height data suggests that bottom friction dominates dissipation at high Rew but not at low Rew. Predictions of near-shore wave height based on offshore wave height and a rough formulation for fw were quite accurate, with errors about half as great as those based on the smooth formulation for fw. Researchers often assume that the wave boundary layer is smooth for settings with fine-grained sediments. At this site, use of a smooth fw results in an underestimate of wave shear stress by a factor of 2 for typical waves and as much as 5 for more energetic waves. It also inadequately captures the effectiveness of the mudflats in protecting the shoreline through wave attenuation.

  11. Designing attenuators for total-body irradiation using virtual simulation. (United States)

    Corns, R; Evans, M; Olivares, M; Dyke, L; Podgorsak, E B; Freeman, C R


    In total-body photon irradiation, the lungs are the most commonly shielded organ. Lung compensators are often designed by using high-energy portal films. Other organs, such as the kidneys and liver, are poorly visualized in portal films due to their unit-density composition. A computed tomography-based technique to design kidney and liver attenuators involves outlining these organs in a virtual simulation. The position and the shape of the attenuator are then determined from a digitally-reconstructed radiograph. Appropriate attenuator thickness is determined from measured transmission curves. This article provides a summary of this technique for total-body photon irradiation in a 4-MV photon beam.

  12. MNAtoolbox: A Monitored Natural Attenuation Site Screening Program

    Energy Technology Data Exchange (ETDEWEB)

    Borns, David J.; Brady, Patrick V.; Brady, Warren D.; Krupka, Kenneth M.; Spalding, Brian P.; Waters, Robert D.; Zhang, Pengchu


    Screening of sites for the potential application and reliance upon monitored natural attenuation (MNA) can be done using MNAtoolbox, a web-based tool for estimating extent of biodegradation, chemical transformation, and dilution. MNAtoolbox uses site-specific input data, where available (default parameters are taken from the literature), to roughly quantify the nature and extent of attenuation at a particular site. Use of MNAtoolbox provides 3 important elements of site evaluation: (1) Identifies likely attenuation pathways, (2) Clearly identifies sites where MNA is inappropriate, and (3) Evaluates data requirements for subsequent reliance on MNA as a sole or partial corrective action.

  13. Photon attenuation properties of some thorium, uranium and plutonium compounds

    Energy Technology Data Exchange (ETDEWEB)

    Singh, V. P.; Badiger, N. M. [Karnatak University, Department of Physics, Dharwad-580003, Karnataka (India); Vega C, H. R., E-mail: [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico)


    Mass attenuation coefficients, effective atomic numbers, effective electron densities for nuclear materials; thorium, uranium and plutonium compounds have been studied. The photon attenuation properties for the compounds have been investigated for partial photon interaction processes by photoelectric effect, Compton scattering and pair production. The values of these parameters have been found to change with photon energy and interaction process. The variations of mass attenuation coefficients, effective atomic number and electron density with energy are shown graphically. Moreover, results have shown that these compounds are better shielding and suggesting smaller dimensions. The study would be useful for applications of these materials for gamma ray shielding requirement. (Author)

  14. Elemental analysis by means of X-ray attenuation measurements (United States)

    Cesareo, Roberto; Giannini, Marino


    Radioactive sources of 109Cd, 241Am and 57Co were employed to measure the attenuation coefficient of biological materials such as whole blood, red blood cells, plasma, urine, water and of materials of interest for computed tomography, such as plexiglas, polyethylene, nylon, teflon, etc. The experimental errors range between 0.3% and 1%. A method is also presented which allows quantitative analysis of materials by measuring their attenuation coefficient at various monoenergetic X-ray energies. As an example, attenuation measurements at 60 keV and 122 keV were employed in order to determine the concentration of lead and copper in silver alloys.

  15. Ultrasonic attenuation measurements determine onset, degree, and completion of recrystallization (United States)

    Generazio, E. R.


    Ultrasonic attenuation was measured for cold worked Nickel 200 samples annealed at increasing temperatures. Localized dislocation density variations, crystalline order and volume percent of recrystallized phase were determined over the anneal temperature range using transmission electron microscopy, X-ray diffraction, and metallurgy. The exponent of the frequency dependence of the attenuation was found to be a key variable relating ultrasonic attenuation to the thermal kinetics of the recrystallization process. Identification of this key variable allows for the ultrasonic determination of onset, degree, and completion of recrystallization.

  16. Quantum Physics


    Haroche, Serge


    Mr Administrator,Dear colleagues,Ladies and gentlemen, “I think I can safely say that nobody understands quantum mechanics”. This statement, made by physicist Richard Feynman, expresses a paradoxical truth about the scientific theory that revolutionised our understanding of Nature and made an extraordinary contribution to our means of acting on and gaining information about the world. In this lecture, I will discuss quantum physics with you by attempting to resolve this paradox. And if I don’...

  17. Exotic Physics

    CERN Document Server

    Sigamani, Michael


    A selection of results for searches for exotic physics at the LHC are presented. These include a search for massive resonances, dark matter with a high energy jet in association with large missing transverse momentum, long-lived neutral particles, and narrow dijet resonances. The results are based on 20/fb of LHC proton-proton collisions at sqrt(s) = 8 TeV taken with the CMS detector.

  18. Singleton physics

    CERN Document Server

    Flato, M; Sternheimer, D; Flato, Moshe; Fronsdal, Christian; Sternheimer, Daniel


    We review the developments in the past twenty years (which are based on our deformation philosophy of physical theories) dealing with elementary particles composed of singletons in anti De Sitter space-time. The study starts with the kinematical aspects (especially for massless particles) and extends to the beginning of a field theory of composite elementary particles and its relations with conformal field theory (including very recent developments).


    Energy Technology Data Exchange (ETDEWEB)

    Looney, B; Karen Vangelas, K; Karen-M Adams, K; Francis H. Chappelle; Tom O. Early; Claire H. Sink


    removal is needed or when to turn off active remediation and transition to MNA. It cannot be used to evaluate potential enhancement options (unless a long period of post enhancement monitoring is planned). It provides only indirect information about process and treats the plume as a ''black box''. The empirical approach has the advantage that, when sufficient monitoring data are available, the attenuation capacity can be defined inexpensively and with a high degree of certainty. Alternatively, a deterministic approach can be used to assess mass balance and plume stability. In this approach, the physical, chemical, and biological attenuation processes are used to assess contaminant loading and attenuation. The deterministic approach has the advantage that, when sufficient hydrologic, geochemical, and microbiological data are available, it is possible to project how a system will respond to contaminant removal actions or enhancements of natural attenuation processes. The ''black box'' of the plume is taken apart, quantified, and put back together again. The disadvantage of the deterministic approach is that it is difficult to measure all or most of the relevant hydrologic, geochemical, and biological parameters with any certainty. Case studies over the past decade demonstrate that empirical and deterministic approaches to MNA/EA are not mutually exclusive. These studies document that improved decision support and efficiency result by combining these methods based on the individual challenges presented by a given site. Whenever possible, the empirical approach is used to quantify mass loading and attenuation capacity (mass of contaminant/unit time) at particular sites. This is the most effective way to demonstrate the efficiency of ongoing natural attenuation processes in accordance with current regulatory guidance. But in addition, the monitoring well networks needed to apply the empirical approach can also yield estimates of the

  20. Licking microstructure reveals rapid attenuation of neophobia. (United States)

    Monk, Kevin J; Rubin, Benjamin D; Keene, Jennifer C; Katz, Donald B


    Many animals hesitate when initially consuming a novel food and increase their consumption of that food between the first and second sessions of access-a process termed attenuation of neophobia (AN). AN has received attention as a model of learning and memory; it has been suggested that plasticity resulting from an association of the novel tastant with "safe outcome" results in a change in the neural response to the tastant during the second session, such that consumption increases. Most studies have reported that AN emerges only an hour or more after the end of the first exposure to the tastant, consistent with what is known of learning-related plasticity. But these studies have typically measured consumption, rather than real-time behavior, and thus the possibility exists that a more rapidly developing AN remains to be discovered. Here, we tested this possibility, examining both consumption and individual lick times in a novel variant of a brief-access task (BAT). When quantified in terms of consumption, data from the BAT accorded well with the results of a classic one-bottle task-both revealed neophobia/AN specific to higher concentrations (for instance, 28mM) of saccharin. An analysis of licking microstructure, however, additionally revealed a real-time correlate of neophobia-an explicit tendency, similarly specific for 28-mM saccharin, to cut short the initial bout of licks in a single trial (compared with water). This relative hesitancy (i.e., the shortness of the first lick bout to 28-mM saccharin compared with water) that constitutes neophobia not only disappeared between sessions but also gradually declined in magnitude across session 1. These data demonstrate that the BAT accurately measures AN, and that aspects of AN-and the processes underlying familiarization-begin within minutes of the very first taste.

  1. Introducing simultaneous spatial resolution and attenuation correction after scatter removal in SPECT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Younes, R.B.; Mas, J.; Pousse, A.; Bidet, R. (Laboratoire de Biophysique et de Medecine Nucleaire, Besancon Cedex (France)); Hannequin, P. (Centre d' Imagerie Nucleaire, Annecy (France))


    A new approach to simultaneous spatial resolution and attenuation correction in SPECT imaging is presented. Before these corrections, scatter is removed on the projections. This removal is performed by spectral constrained factor analysis. The innovation reported here is the use of the different impulse responses of the system, according to the source-detector distance, and their integration in a generalized version of the Chang attenuation correction method. This novel algorithm is evaluated on computed and physical phantoms. In the computer-simulated phantom, the count rates after full-processing are very close to the initial values. In the physical phantom, the contrast is increased by 1.8 after full processing. The activity profiles drawn both on raw projections and reconstructed slices demonstrate the effectiveness of the algorithm for the restoration of spatial resolution. Furthermore, the method improves the quality of the images greatly. A clinical study is also presented. When the whole procedure is applied, the resulting slice matches the corresponding computed tomographic scan very well, which is not the case with the usual back-projected images. The process is fully automatic and the computing time performance allows its daily use for single photon emission tomographic examinations. (author).

  2. Solar Physics - Plasma Physics Workshop (United States)

    Baum, P. J.; Beckers, J. M.; Newman, C. E.; Priest, E. R.; Rosenberg, H.; Smith, D. F.; Sturrock, P. A.; Wentzel, D. G.


    A summary of the proceedings of a conference whose purpose was to explore plasma physics problems which arise in the study of solar physics is provided. Sessions were concerned with specific questions including the following: (1) whether the solar plasma is thermal or non-themal; (2) what spectroscopic data is required; (3) what types of magnetic field structures exist; (4) whether magnetohydrodynamic instabilities occur; (5) whether resistive or non-magnetohydrodynamic instabilities occur; (6) what mechanisms of particle acceleration have been proposed; and (7) what information is available concerning shock waves. Very few questions were answered categorically but, for each question, there was discussion concerning the observational evidence, theoretical analyses, and existing or potential laboratory and numerical experiments.

  3. Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review

    NARCIS (Netherlands)

    Bauer, M.E.; Muller, G.C.; Correa, B.L.; Vianna, P.; Turner, J.E.; Bosch, J.A.


    There is evidence suggesting that immunosenescence can be accelerated by external factors such as chronic stress. Here we review potential psychoneuroendocrine determinants of premature aging of the immune system and discuss available interventions aimed at attenuating immunosenescence. Chronic stre

  4. Biochanin-A attenuates neuropathic pain in diabetic rats

    Directory of Open Access Journals (Sweden)

    Venkateswarlu Chundi


    Conclusion: Biochanin-A demonstrated better efficacy in reversing mechanical allodynia than mechanical hyperalgesia. Biochanin-A could be a good drug candidate for further studies to establish the mechanism of attenuation of neuropathic pain.


    A natural attenuation model that simulates the aerobic and anaerobic biodegradation of fuel hydrocarbons was developed. The resulting model, BIOPLUME III, demonstrates the importance of biodegradation in reducing contaminant concentrations in ground water. In hypothetical simulat...


    Institute of Scientific and Technical Information of China (English)

    Zhang Qing-he; Onyx W.H. Wai; Joseph H. W. Lee


    A two-layer model, with the upper layer being the perfect fluid and the lower layer being the pseudo-plastic fluid describing water wave attenuation over mud bed, was established. A simplified method based on the principle of equivalent work was applied to solve the boundary value problems. The computational results of the model show that the two-layer perfect fluid model and the perfect-viscous fluid model are all special cases of the present model. The complex nonlinear properties of wave attenuation over mud bed, can be explained by the present model, e.g., the wave dissipation rate decreases with the wave height in certain cases, while the small wave propagates over mud bed with less energy dissipation and large wave attenuates rapidly in other cases. Other factors influencing the wave attenuation were also discussed.

  7. Earth/Mars Landing Impact Attenuation Using Foam Project (United States)

    National Aeronautics and Space Administration — On a previous ICA, a test correlated excel based software tool was developed using the innovative Stress?Energy method to better model impact attenuation using...

  8. 49 CFR 227.117 - Hearing protector attenuation. (United States)


    ... exposure to an 8-hour TWA of 90 decibels or lower, as required by § 227.115. (c) For employees who have...-weighted average of 85 decibels or lower. (d) The adequacy of hearing protector attenuation shall be...

  9. Dose reduction using a dynamic, piecewise-linear attenuator

    Energy Technology Data Exchange (ETDEWEB)

    Hsieh, Scott S., E-mail: [Department of Radiology, Stanford University, Stanford, California 94305 and Department of Electrical Engineering, Stanford University, Stanford, California 94305 (United States); Fleischmann, Dominik [Department of Radiology, Stanford University, Stanford, California 94305 (United States); Pelc, Norbert J. [Department of Radiology, Stanford University, Stanford, California 94305 and Department of Bioengineering, Stanford University, Stanford, California 94305 (United States)


    Purpose: The authors recently proposed a dynamic, prepatient x-ray attenuator capable of producing a piecewise-linear attenuation profile customized to each patient and viewing angle. This attenuator was intended to reduce scatter-to-primary ratio (SPR), dynamic range, and dose by redistributing flux. In this work the authors tested the ability of the attenuator to reduce dose and SPR in simulations. Methods: The authors selected four clinical applications, including routine full field-of-view scans of the thorax and abdomen, and targeted reconstruction tasks for an abdominal aortic aneurysm and the pancreas. Raw data were estimated by forward projection of the image volume datasets. The dynamic attenuator was controlled to reduce dose while maintaining peak variance by solving a convex optimization problem, assuminga priori knowledge of the patient anatomy. In targeted reconstruction tasks, the noise in specific regions was given increased weighting. A system with a standard attenuator (or “bowtie filter”) was used as a reference, and used either convex optimized tube current modulation (TCM) or a standard TCM heuristic. The noise of the scan was determined analytically while the dose was estimated using Monte Carlo simulations. Scatter was also estimated using Monte Carlo simulations. The sensitivity of the dynamic attenuator to patient centering was also examined by shifting the abdomen in 2 cm intervals. Results: Compared to a reference system with optimized TCM, use of the dynamic attenuator reduced dose by about 30% in routine scans and 50% in targeted scans. Compared to the TCM heuristics which are typically used withouta priori knowledge, the dose reduction is about 50% for routine scans. The dynamic attenuator gives the ability to redistribute noise and variance and produces more uniform noise profiles than systems with a conventional bowtie filter. The SPR was also modestly reduced by 10% in the thorax and 24% in the abdomen. Imaging with the dynamic

  10. Women in Physics. (United States)

    Roth, Laura M.; O'Fallon, Nancy M.

    This booklet presents information about career opportunities for women in physics. Included are summaries of research areas in physics (optical physics, solid-state physics, materials science, nuclear physics, high-energy physics, astrophysics, cryogenics, plasma physics, biophysics, atmospheric physics) and differences between theory and…

  11. Theoretical physics

    CERN Document Server

    Joos, Georg


    Among the finest, most comprehensive treatments of theoretical physics ever written, this classic volume comprises a superb introduction to the main branches of the discipline and offers solid grounding for further research in a variety of fields. Students will find no better one-volume coverage of so many essential topics; moreover, since its first publication, the book has been substantially revised and updated with additional material on Bessel functions, spherical harmonics, superconductivity, elastomers, and other subjects.The first four chapters review mathematical topics needed by theo

  12. Attenuation of 3CM Microwaves Due to Artificial Rain

    Directory of Open Access Journals (Sweden)

    J. K. Singh


    Full Text Available Observations to study the variation of attenuation of 3cm waves due to falling of water or artificial rain are confined to the high rates of precipitation and short distance between the transmitter and receiver, due to low power of the microwave generator. A comparison of these observations and those recorded by others shows that the attenuation increases nonlinearly with the intensity of artificial rainfall which is generally assumed to be linear for the observations at lower rates of precipitation.

  13. An analysis of seismic attenuation in random porous media

    Institute of Scientific and Technical Information of China (English)


    The attenuation of seismic wave in rocks has been one of the interesting research topics, but till now no poroelasticity models can thoroughly explain the strong attenuation of wave in rocks. In this paper, a random porous medium model is designed to study the law of wave propagation in complex rocks based on the theory of Biot poroelasticity and the general theory of stochastic process. This model sets the density of grain, porosity, permeability and modulus of frame as random parameters in space, and only one fluid infiltrates in rocks for the sake of better simulation effect in line with real rocks in earth strata. Numerical simulations are implemented. Two different inverse quality factors of fast P-wave are obtained by different methods to assess attenuation through records of virtual detectors in wave field (One is amplitude decay method in time domain and the other is spectral ratio method in frequency domain). Comparing the attenuation results of random porous medium with those of homogeneous porous medium, we conclude that the attenuation of seismic wave of homogeneous porous medium is far weaker than that of random porous medium. In random porous media, the higher heterogeneous level is, the stronger the attenuation becomes, and when heterogeneity σ = 0.15 in simulation, the attenuation result is consistent with that by actual observation. Since the central frequency (50 Hz) of source in numerical simulation is in earthquake band, the numerical results prove that heterogeneous porous structure is one of the important factors causing strong attenuation in real stratum at intermediate and low frequency.

  14. Characterizing X-ray Attenuation of Containerized Cargo

    Energy Technology Data Exchange (ETDEWEB)

    Birrer, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wang, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    X-ray inspection systems can be used to detect radiological and nuclear threats in imported cargo. In order to better understand performance of these systems, the attenuation characteristics of imported cargo need to be determined. This project focused on developing image processing algorithms for segmenting cargo and using x-ray attenuation to quantify equivalent steel thickness to determine cargo density. These algorithms were applied to over 450 cargo radiographs. The results are summarized in this report.

  15. Impact of Scattering Model on Disdrometer Derived Attenuation Scaling (United States)

    Zemba, Michael; Luini, Lorenzo; Nessel, James; Riva, Carlo


    NASA Glenn Research Center (GRC), the Air Force Research Laboratory (AFRL), and the Politecnico di Milano (POLIMI) are currently entering the third year of a joint propagation study in Milan, Italy utilizing the 20 and 40 GHz beacons of the Alphasat TDP#5 Aldo Paraboni scientific payload. The Ka- and Q-band beacon receivers were installed at the POLIMI campus in June of 2014 and provide direct measurements of signal attenuation at each frequency. Collocated weather instrumentation provides concurrent measurement of atmospheric conditions at the receiver; included among these weather instruments is a Thies Clima Laser Precipitation Monitor (optical disdrometer) which records droplet size distributions (DSD) and droplet velocity distributions (DVD) during precipitation events. This information can be used to derive the specific attenuation at frequencies of interest and thereby scale measured attenuation data from one frequency to another. Given the ability to both predict the 40 gigahertz attenuation from the disdrometer and the 20 gigahertz time-series as well as to directly measure the 40 gigahertz attenuation with the beacon receiver, the Milan terminal is uniquely able to assess these scaling techniques and refine the methods used to infer attenuation from disdrometer data. In order to derive specific attenuation from the DSD, the forward scattering coefficient must be computed. In previous work, this has been done using the Mie scattering model, however, this assumes a spherical droplet shape. The primary goal of this analysis is to assess the impact of the scattering model and droplet shape on disdrometer-derived attenuation predictions by comparing the use of the Mie scattering model to the use of the T-matrix method, which does not assume a spherical droplet. In particular, this paper will investigate the impact of these two scattering approaches on the error of the resulting predictions as well as on the relationship between prediction error and rain rate.

  16. Attenuation of Scalar Fluxes Measured with Spatially-displaced Sensors (United States)

    Horst, T. W.; Lenschow, D. H.


    Observations from the Horizontal Array Turbulence Study (HATS) field program are used to examine the attenuation of measured scalar fluxes caused by spatial separation between the vertical velocity and scalar sensors. The HATS data show that flux attenuation for streamwise, crosswind, and vertical sensor displacements are each a function of a dimensionless, stability-dependent parameter n m multiplied by the ratio of sensor displacement to measurement height. The scalar flux decays more rapidly with crosswind displacements than for streamwise displacements and decays more rapidly for stable stratification than for unstable stratification. The cospectral flux attenuation model of Kristensen et al. agrees well with the HATS data for streamwise sensor displacements, although it is necessary to include a neglected quadrature spectrum term to explain the observation that flux attenuation is often less with the scalar sensor downwind of the anemometer than for the opposite configuration. A simpler exponential decay model provides good estimates for crosswind sensor displacements, as well as for streamwise sensor displacements with stable stratification. A model similar to that of Lee and Black correctly predicts flux attenuation for a combination of streamwise and crosswind displacements, i.e. as a function of wind direction relative to the sensor displacement. The HATS data for vertical sensor displacements extend the near-neutral results of Kristensen et al. to diabatic stratification and confirm their finding that flux attenuation is less with the scalar sensor located below the anemometer than if the scalar sensor is displaced an equal distance either horizontally or above the anemometer.

  17. Proteomic Analysis of Pathogenic and Attenuated Alcelaphine Herpesvirus 1▿ (United States)

    Dry, Inga; Haig, David M.; Inglis, Neil F.; Imrie, Lisa; Stewart, James P.; Russell, George C.


    The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs. In tissue culture, AlHV-1 is initially predominantly cell associated and virulent but on extended culture becomes cell-free and attenuated. We wanted to determine what changes in protein composition had taken place during the transition from virulent to attenuated virus in culture. Purified virus preparations were fractionated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and proteins were analyzed by liquid chromatography-electrospray ionization-tandem mass spectrometry. Peptides were identified in serial gel slices by using MASCOT software to interrogate virus-specific and nonredundant sequence databases. Twenty-three AlHV-1-encoded proteins and six cellular proteins were identified in the attenuated and virulent viruses. Two polypeptides were detected in only the virulent virus preparations, while one other protein was found in only the attenuated virus. Two of these virus-specific proteins were identified by a single peptide, suggesting that these may be low-abundance virion proteins rather than markers of attenuation or pathogenesis. The results suggest that attenuation of AlHV-1 is not the result of gross changes in the composition of the virus particle but probably due to altered viral gene expression in the infected cell. PMID:18353942

  18. Two media method for linear attenuation coefficient determination of irregular soil samples; Metodo dos dois meios para a determinacao do coeficiente de atenuacao linear de amostras irregulares de solos

    Energy Technology Data Exchange (ETDEWEB)

    Vici, Carlos Henrique Georges


    In several situations of nuclear applications, the knowledge of gamma-ray linear attenuation coefficient for irregular samples is necessary, such as in soil physics and geology. This work presents the validation of a methodology for the determination of the linear attenuation coefficient ({mu}) of irregular shape samples, in such a way that it is not necessary to know the thickness of the considered sample. With this methodology irregular soil samples (undeformed field samples) from Londrina region, north of Parana were studied. It was employed the two media method for the {mu} determination. It consists of the {mu} determination through the measurement of a gamma-ray beam attenuation by the sample sequentially immersed in two different media, with known and appropriately chosen attenuation coefficients. For comparison, the theoretical value of {mu} was calculated by the product of the mass attenuation coefficient, obtained by the WinXcom code, and the measured value of the density sample. This software employs the chemical composition of the samples and supplies a table of the mass attenuation coefficients versus the photon energy. To verify the validity of the two media method, compared with the simple gamma ray transmission method, regular pome stone samples were used. With these results for the attenuation coefficients and their respective deviations, it was possible to compare the two methods. In this way we concluded that the two media method is a good tool for the determination of the linear attenuation coefficient of irregular materials, particularly in the study of soils samples. (author)

  19. Novel point mutations attenuate autotaxin activity

    Directory of Open Access Journals (Sweden)

    Stracke Mary L


    Full Text Available Abstract Background The secreted enzyme autotaxin (ATX stimulates tumor cell migration, tumorigenesis, angiogenesis, and metastasis. ATX hydrolyzes nucleotides, but its hydrolysis of lysophospholipids to produce lysophosphatidic acid (LPA accounts for its biological activities. ATX has been identified only as a constitutively active enzyme, and regulation of its activity is largely unexplored. In spite of its presence in plasma along with abundant putative substrate LPC, the product LPA is found in plasma at unexpectedly low concentrations. It is plausible that the LPA-producing activity of ATX is regulated by its expression and by access to substrate(s. For this reason studying the interaction of enzyme with substrate is paramount to understanding the regulation of LPA production. Results In this study we determine ATX hydrolytic activities toward several artificial and natural substrates. Two novel point mutations near the enzyme active site (H226Q and H434Q confer attenuated activity toward all substrates tested. The Vmax for LPC compounds depends upon chain length and saturation; but this order does not differ among wild type and mutants. However the mutant forms show disproportionately low activity toward two artificial substrates, pNpTMP and FS-3. The mutant forms did not significantly stimulate migration responses at concentrations that produced a maximum response for WT-ATX, but this defect could be rescued by inclusion of exogenous LPC. Conclusion H226Q-ATX and H434Q-ATX are the first point mutations of ATX/NPP2 demonstrated to differentially impair substrate hydrolysis, with hydrolysis of artificial substrates being disproportionately lower than that of LPC. This implies that H226 and H434 are important for substrate interaction. Assays that rely on hydrolyses of artificial substrates (FS-3 and pNpTMP, or that rely on hydrolysis of cell-derived substrate, might fail to detect certain mutated forms of ATX that are nonetheless capable of

  20. Carbon nanotubes attenuate cancer and improve healing (United States)

    Wailes, Elizabeth Marguerite

    Breast cancer is the most common cancer in American women and the second largest cause of their cancer mortality. Resection of the primary tumor can greatly improve the prognosis, but if any of the cancerous cells remain, the patient is still at risk. This work investigates the ability of high aspect ratio nanoparticles to both heal injured tissue and attenuate cancer cells' aggression. To assess different particles' utility, carbon nanoparticles were evaluated in a fibroblast and collagen gel model of wound contraction, then polymeric nanoparticles were synthesized and tested similarly. The carbon particles, multi-walled nanotubes (MWNT) in particular, performed the best, strongly inhibiting pathological wound contraction, increasing cell viability, and decreasing reactive oxygen species. Later, carbon nanoparticle coatings with or without collagen were tested with breast cancer cells to assess adhesion, migration, and E-cadherin expression of the cells. The collagen-MWNT coatings were able to increase cancer cell adhesion to their substrate, decrease migration, increase E-cadherin expression, and also increase autophagy. The coatings effected all these changes without increasing proliferation of the cancer cells or affecting non-tumorigenic breast cells. To examine how these two sets of results might act together, co-cultures were then created with both fibroblasts and cancer cells in collagen gels with or without MWNT. The cells' movement and matrix metalloproteinase (MMP) expression were measured to gauge the cells' interaction in that environment, as fibroblasts can encourage or suppress metastasis depending on their behavior. The MWNT were able to decrease cancer cell movement, particularly their invasion into the gel, and selectively promote cancer cell death without harming the non-tumorigenic cells. They also decreased MMP expression. Finally, early in vivo work was undertaken to determine how the collagen-nanoparticle gels are able to control cancer in

  1. Shear wave velocity, seismic attenuation, and thermal structure of the continental upper mantle (United States)

    Artemieva, I.M.; Billien, M.; Leveque, J.-J.; Mooney, W.D.


    Seismic velocity and attenuation anomalies in the mantle are commonly interpreted in terms of temperature variations on the basis of laboratory studies of elastic and anelastic properties of rocks. In order to evaluate the relative contributions of thermal and non-thermal effects on anomalies of attenuation of seismic shear waves, QS-1, and seismic velocity, VS, we compare global maps of the thermal structure of the continental upper mantle with global QS-1 and Vs maps as determined from Rayleigh waves at periods between 40 and 150 S. We limit the comparison to three continental mantle depths (50, 100 and 150 km), where model resolution is relatively high. The available data set does not indicate that, at a global scale, seismic anomalies in the upper mantle are controlled solely by temperature variations. Continental maps have correlation coefficients of temperatures: most cratonic regions show high VS and QS and low T, while most active regions have seismic and thermal anomalies of the opposite sign. The strongest inverse correlation is found at a depth of 100 km, where the attenuation model is best resolved. Significantly, at this depth, the contours of near-zero QS anomalies approximately correspond to the 1000 ??C isotherm, in agreement with laboratory measurements that show a pronounced increase in seismic attenuation in upper mantle rocks at 1000-1100 ??C. East-west profiles of VS, QS and T where continental data coverage is best (50??N latitude for North America and 60??N latitude for Eurasia) further demonstrate that temperature plays a dominant, but non-unique, role in determining the value of lithospheric VS and QS. At 100 km depth, where the resolution of seismic models is the highest, we compare observed seismic VS and QS with theoretical VST and QST values, respectively, that are calculated solely from temperature anomalies and constrained by experimental data on temperature dependencies of velocity and attenuation. This comparison shows that

  2. Physical modeling and analysis of P-wave attenuation anisotropy in transversely isotropic media

    Digital Repository Service at National Institute of Oceanography (India)

    Zhu, Y.; Tsvankin, I.; Dewangan, P.; Van Wijk, K.

    direction) to the isotropy plane (fast direction). Inversion of the coefficient A using the Christoffel equation yields large negative values of the parameters epsilon sub(Q) and delta sub(Q). The robustness of our results critically depends on several...

  3. DUNE Physics

    Energy Technology Data Exchange (ETDEWEB)

    Strait, James [Fermilab


    The Deep Underground Neutrino Experiment is a worldwide effort to build a next-generation long-baseline neutrino experiment with a neutrino beam and near detector at Fermilab and a far detector at the Sanford Underground Research Facility 1,300 km from Fermilab. It is a merger of previous efforts and other interested parties to build, operate and exploit a staged 40-kt liquid argon detector and a high precision near detector exposed to a high-power, broad-band neutrino beam. The goals of the experiment are precision oscillation measurements, including CP violation and neutrino mass hierarchy determination, search for nucleon decay, and neutrino astrophysics, as well as precision neutrino physics at the near site.

  4. Physical conditions

    DEFF Research Database (Denmark)

    Nielsen, Birte Lindstrøm; Appleby, M.C.; Waran, N.K.


    The physical environment of an animal is sometimes altered if it is found to cause problems for animal welfare. These changes are commonly quite specific (making changes to space, food, water, aspects of housing design such as flooring, or to other environmental factors such as air quality) and may...... be effective in preventing injuries or disease. However, such measures may not be implemented in practice (usually for economic reasons), and where implemented may cause other problems, as when concern for hygiene leads to animals being kept in barren conditions. Numerous ways have also been tried to diversify...... feeding methods in order to improve animal welfare, but specific changes to the environment such as these often have widespread effects, some of which may be detrimental. For example, inclusion of novel pen structures meant to enrich the environment may lead to increased aggression. A more general...

  5. LHC Physics

    CERN Multimedia

    CERN Bulletin


    From quarks to yet unknown particles, CERN continues to explore new frontiers in physics. Thanks to some of the most complex instruments ever made in a laboratory, Nature can reveal its inner secrets to the scientists.   Mass is the amount of material in an object. Newton showed us that weight is proportional to mass, and Einstein showed that energy is related to mass through the famous equation E = mc2. When it comes to elementary particles, physicists are dealing with a very fundamental question: where does the mass come from?  Why do particles with no known structure have mass? The answer may lie in the so-called Higgs mechanism. According to this theory, a medium - called the Higgs field - spreads through all the Universe at all times. Particles acquire their mass by interacting with this field, such that those that interact strongly are heavier than those having a weaker interaction. The Higgs boson is th...

  6. Continuum Physics

    CERN Document Server

    Hertel, Peter


    This small book on the properties of continuously distributed matter covers a huge field. It sets out the governing principles of continuum physics and illustrates them by carefully chosen examples. These examples comprise structural mechanics and elasticity, fluid media, electricity and optics, thermoelectricity, fluctuation phenomena and more, from Archimedes' principle via Brownian motion to white dwarfs. Metamaterials, pattern formation by reaction-diffusion and surface plasmon polaritons are dealt with as well as classical topics such as Stokes' formula, beam bending and buckling, crystal optics and electro- and magnetooptic effects, dielectric waveguides, Ohm's law, surface acoustic waves, to mention just some.   The set of balance equations for content, flow and production of particles, mass, charge, momentum, energy and entropy is augmented by material, or constitutive equations. They describe entire classes of materials, such as viscid fluids and gases, elastic media, dielectrics or electrical con...

  7. Atomic physics

    Energy Technology Data Exchange (ETDEWEB)

    Livingston, A.E.; Kukla, K.; Cheng, S. [Univ. of Toledo, OH (United States)] [and others


    In a collaboration with the Atomic Physics group at Argonne and the University of Toledo, the Atomic Physics group at the University of Notre Dame is measuring the fine structure transition energies in highly-charged lithium-like and helium-like ions using beam-foil spectroscopy. Precise measurements of 2s-2p transition energies in simple (few-electron) atomic systems provide stringent tests of several classes of current atomic- structure calculations. Analyses of measurements in helium-like Ar{sup 16+} have been completed, and the results submitted for publication. A current goal is to measure the 1s2s{sup 3}S{sub 1} - 1s2p{sup 3}P{sub 0} transition wavelength in helium-like Ni{sup 26+}. Measurements of the 1s2s{sup 2}S{sub 1/2} - 1s2p{sup 2}P{sub 1/2,3/2} transition wavelengths in lithium-like Kr{sup 33+} is planned. Wavelength and lifetime measurements in copper-like U{sup 63+} are also expected to be initiated. The group is also participating in measurements of forbidden transitions in helium-like ions. A measurement of the lifetime of the 1s2s{sup 3}S{sub 1} state in Kr{sup 34+} was published recently. In a collaboration including P. Mokler of GSI, Darmstadt, measurements have been made of the spectral distribution of the 2E1 decay continuum in helium-like Kr{sup 34+}. Initial results have been reported and further measurements are planned.

  8. Imaging the attenuation coefficients of positron beams in matter: positron attenuation tomography

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Charles [Siemens Healthcare, Knoxville, TN (United States)


    A new positron annihilation imaging modality is described that enables nondestructive measurement of the linear attenuation coefficients (LACs) of positron beams in heterogeneous materials. This positron attenuation tomography (PAT) technique utilizes a positron emission tomography (PET) system embedded within a uniform static magnetic field, such as is found in integrated PET/MRI scanners. A Ga68-generated positron beam constrained by a 3T magnetic field penetrates objects placed within the scanner. The positrons slow down and annihilate within the object. The resulting annihilation distribution is tomographically imaged by the PET camera. This image may be interpreted as a map of the product of the positron beam's flux and its LAC at each point in the volume. It is shown that under certain easily achieved conditions this image can be decomposed into separate maps of the flux and the LACs, without need for auxiliary measurements. Although these LACs may depend on both beam and material properties, a beam softening correction is demonstrated that effectively removes the dependence on beam variation, leaving a relative LAC that is characteristic of the material. Unlike x-ray, gamma-ray or other transmission techniques, PAT does not require the penetration of the beam entirely through the object. High resolution and high contrast images of positron beam LACs in objects may be produced over nearly the full range of the positron beam, which for Ga68 beta-rays in a 3T field is about 0.5 g/cm{sup 2}. The first examples of PAT images and an initial characterization of performance will be presented.

  9. Laboratory measurements of physical, chemical, and optical characteristics of Lake Chicot sediment waters (United States)

    Witte, W. G.; Whitlock, C. H.; Usry, J. W.; Morris, W. D.; Gurganus, E. A.


    Reflectance, chromaticity, diffuse attenuation, beam attenuation, and several other physical and chemical properties were measured for various water mixtures of lake bottom sediment. Mixture concentrations range from 5 ppm to 700 ppm by weight of total suspended solids in filtered deionized tap water. Upwelled reflectance is a nonlinear function of remote sensing wave lengths. Near-infrared wavelengths are useful for monitoring highly turbid waters with sediment concentrations above 100 ppm. It is found that both visible and near infrared wavelengths, beam attenuation correlates well with total suspended solids ranging over two orders of magnitude.

  10. Brunenders: a partially attenuated historic poliovirus type I vaccine strain. (United States)

    Sanders, Barbara P; Liu, Ying; Brandjes, Alies; van Hoek, Vladimir; de Los Rios Oakes, Isabel; Lewis, John; Wimmer, Eckard; Custers, Jerome H H V; Schuitemaker, Hanneke; Cello, Jeronimo; Edo-Matas, Diana


    Brunenders, a type I poliovirus (PV) strain, was developed in 1952 by J. F. Enders and colleagues through serial in vitro passaging of the parental Brunhilde strain, and was reported to display partial neuroattenuation in monkeys. This phenotype of attenuation encouraged two vaccine manufacturers to adopt Brunenders as the type I component for their inactivated poliovirus vaccines (IPVs) in the 1950s, although today no licensed IPV vaccine contains Brunenders. Here we confirmed, in a transgenic mouse model, the report of Enders on the reduced neurovirulence of Brunenders. Although dramatically neuroattenuated relative to WT PV strains, Brunenders remains more virulent than the attenuated oral vaccine strain, Sabin 1. Importantly, the neuroattenuation of Brunenders does not affect in vitro growth kinetics and in vitro antigenicity, which were similar to those of Mahoney, the conventional type I IPV vaccine strain. We showed, by full nucleotide sequencing, that Brunhilde and Brunenders differ at 31 nucleotides, eight of which lead to amino acid changes, all located in the capsid. Upon exchanging the Brunenders capsid sequence with that of the Mahoney capsid, WT neurovirulence was regained in vivo, suggesting a role for the capsid mutations in Brunenders attenuation. To date, as polio eradication draws closer, the switch to using attenuated strains for IPV is actively being pursued. Brunenders preceded this novel strategy as a partially attenuated IPV strain, accompanied by decades of successful use in the field. Providing data on the attenuation of Brunenders may be of value in the further construction of attenuated PV strains to support the grand pursuit of the global eradication of poliomyelitis.

  11. Characteristics of coda wave attenuation in Yunnan area

    Institute of Scientific and Technical Information of China (English)


    The characteristic of seismic coda wave attenuation in Yunnan area in 7 frequency-bands range from 1 Hz to 20 Hz was estimated by using the local earthquake's waveform data recorded from 22 Yunnan digital seismic stations.Coda attenuation Q-c1 of each station was firstly calculated by single scattering method. Then, mean free path Le and seismic albedo Bo of each station were calculated, and scattering attenuation Q-1s and intrinsic attenuation Q-1i were separated from total attenuation Q-1t by multiple lapse time window analysis based on the multiple scattering model in uniform random isotropic scattering medium. The attenuating characteristics in Yunnan show that most value of Le are in 10~30 km, with maximal within 2~6 Hz;Bo are about 0.5 at 1~2 Hz, but less than 0.5at other frequency-bands, which means Q-1i is comparable with Q-1s at 1~2 Hz, and after 1~2 Hz, Q-1i is greater than Q-1s and dominates the attenuation process. Q-1c is close to Q-1i at other frequency bands except 1~2 Hz.Results show that Q-1 especially Qs-1 varies spatially, Q-1 in eastern Yunnan zone is a bit higher than in northwestern Yunnan zone;northwestern Yunnan zone higher than southwestern Yunnan zone. Comparing with other results in global, Qs-1 in Yunnan is lower than the global average value among these results, Q-1i is higher than the global average value, and Q-1t lies the middle among these results.

  12. Attenuation correction effects on SPECT/CT procedures: phantoms studies. (United States)

    Oliveira, M L; Seren, M E G; Rocha, F C; Brunetto, S Q; Ramos, C D; Button, V L S N


    Attenuation correction is widely used in SPECT/CT (Single Photon Emission Computed Tomography) procedures, especially for imaging of the thorax region. Different compensation methods have been developed and introduced into clinical practice. Most of them use attenuation maps obtained using transmission scanning systems. However, this gives extra dose of radiation to the patient. The purpose of this study was to identify when attenuation correction is really important during SPECT/CT procedures.For this purpose, we used Jaszczak phantom and phantom with three line sources, filled with technetium ((99m)-Tc), with scattering materials, like air, water and acrylic, in different detectors configurations. In all images acquired were applied analytic and iterative reconstruction algorithms; the last one with or without attenuation correction. We analyzed parameters such as eccentricity, contrast and spatial resolution in the images.The best reconstruction algorithm on average was iterative, for images with 128 × 128 and 64 × 64 matrixes. The analytical algorithm was effective only to improve eccentricity in 64 × 64 matrix and matrix in contrast 128 × 128 with low statistics. Turning to the clinical routine examinations, on average, for 128 × 128 matrix and low statistics counting, the best algorithm was the iterative, without attenuation correction,improving in 150% the three parameters analyzed and, for the same matrix size, but with high statistical counting, iterative algorithm with attenuation correction was 25% better than that without correction. We can conclude that using the iterative algorithm with attenuation correction in the water, and its extra dose given, is not justified for the procedures of low statistic counting, being relevant only if the intention is to prioritize contrast in acquisitions with high statistic counting.

  13. Attenuation of trace organic compounds (TOrCs) inbioelectrochemical systems

    KAUST Repository

    Werner, Craig M.


    Microbial fuel cells (MFCs) and microbial electrolysis cells (MECs) are two types of microbial bioelectrochemical systems (BESs) that use microorganisms to convert chemical energy in wastewaters into useful energy products such as (bio)electricity (MFC) or hydrogen gas (MEC). These two systems were evaluated for their capacity to attenuate trace organic compounds (TOrCs), commonly found in municipal wastewater, under closed circuit (current generation) and open circuit (no current generation) conditions, using acetate as the carbon source. A biocide was used to evaluate attenuation in terms of biotransformation versus sorption. The difference in attenuation observed before and after addition of the biocide represented biotransformation, while attenuation after addition of a biocide primarily indicated sorption. Attenuation of TOrCs was similar in MFCs and MECs for eight different TOrCs, except for caffeine and trimethoprim where slightly higher attenuation was observed in MECs. Electric current generation did not enhance attenuation of the TOrCs except for caffeine, which showed slightly higher attenuation under closed circuit conditions in both MFCs and MECs. Substantial sorption of the TOrCs occurred to the biofilm-covered electrodes, but no consistent trend could be identified regarding the physico-chemical properties of the TOrCs tested and the extent of sorption. The octanol-water distribution coefficient at pH 7.4 (log DpH 7.4) appeared to be a reasonable predictor for sorption of some of the compounds (carbamazepine, atrazine, tris(2-chloroethyl) phosphate and diphenhydramine) but not for others (N,N-Diethyl-meta-toluamide). Atenolol also showed high levels of sorption despite being the most hydrophilic in the suite of compounds studied (log DpH 7.4=-1.99). Though BESs do not show any inherent advantages over conventional wastewater treatment, with respect to TOrC removal, overall removals in BESs are similar to that reported for conventional wastewater

  14. Pentoxifylline Attenuates Cardiac Remodeling Induced by Tobacco Smoke Exposure

    Energy Technology Data Exchange (ETDEWEB)

    Minicucci, Marcos; Oliveira, Fernando; Santos, Priscila; Polegato, Bertha; Roscani, Meliza; Fernandes, Ana Angelica; Lustosa, Beatriz; Paiva, Sergio; Zornoff, Leonardo; Azevedo, Paula, E-mail: [Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, São Paulo, SP (Brazil)


    Tobacco smoke exposure is an important risk factor for cardiac remodeling. Under this condition, inflammation, oxidative stress, energy metabolism abnormalities, apoptosis, and hypertrophy are present. Pentoxifylline has anti‑inflammatory, anti-apoptotic, anti-thrombotic and anti-proliferative properties. The present study tested the hypothesis that pentoxifylline would attenuate cardiac remodeling induced by smoking. Wistar rats were distributed in four groups: Control (C), Pentoxifylline (PX), Tobacco Smoke (TS), and PX-TS. After two months, echocardiography, invasive blood pressure measurement, biochemical, and histological studies were performed. The groups were compared by two-way ANOVA with a significance level of 5%. TS increased left atrium diameter and area, which was attenuated by PX. In the isolated heart study, TS lowered the positive derivate (+dp/dt), and this was attenuated by PX. The antioxidants enzyme superoxide dismutase and glutathione peroxidase were decreased in the TS group; PX recovered these activities. TS increased lactate dehydrogenase (LDH) and decreased 3-hydroxyacyl Coenzyme A dehydrogenases (OH-DHA) and citrate synthase (CS). PX attenuated LDH, 3-OH-DHA and CS alterations in TS-PX group. TS increased IL-10, ICAM-1, and caspase-3. PX did not influence these variables. TS induced cardiac remodeling, associated with increased inflammation, oxidative stress, apoptosis, and changed energy metabolism. PX attenuated cardiac remodeling by reducing oxidative stress and improving cardiac bioenergetics, but did not act upon cardiac cytokines and apoptosis.

  15. Frequency-Dependent Attenuation of Blasting Vibration Waves (United States)

    Zhou, Junru; Lu, Wenbo; Yan, Peng; Chen, Ming; Wang, Gaohui


    The dominant frequency, in addition to the peak particle velocity, is a critical factor for assessing adverse effects of the blasting vibration on surrounding structures; however, it has not been fully considered in blasting design. Therefore, the dominant frequency-dependent attenuation mechanism of blast-induced vibration is investigated in the present research. Starting with blasting vibration induced by a spherical charge propagating in an infinite viscoelastic medium, a modified expression of the vibration amplitude spectrum was derived to reveal the frequency dependency of attenuation. Then, ground vibration induced by more complex and more commonly used cylindrical charge that propagates in a semi-infinite viscoelastic medium was analyzed by numerical simulation. Results demonstrate that the absorptive property of the medium results in the frequency attenuation versus distance, whereas a rapid drop or fluctuation occurs during the attenuation of ground vibration. Fluctuation usually appears at moderate to far field, and the dominant frequency generally decreases to half the original value when rapid drop occurs. The decay rate discrepancy between different frequency components and the multimodal structure of vibration spectrum lead to the unsmooth frequency-dependent attenuation. The above research is verified by two field experiments. Furthermore, according to frequency-based vibration standards, frequency drop and fluctuation should be considered when evaluating blast safety. An optimized piecewise assessment is proposed for more accurate evaluation: With the frequency drop point as the breakpoint, the assessment is divided into two independent sections along the propagating path.

  16. Wild type measles virus attenuation independent of type I IFN

    Directory of Open Access Journals (Sweden)

    Horvat Branka


    Full Text Available Abstract Background Measles virus attenuation has been historically performed by adaptation to cell culture. The current dogma is that attenuated virus strains induce more type I IFN and are more resistant to IFN-induced protection than wild type (wt. Results The adaptation of a measles virus isolate (G954-PBL by 13 passages in Vero cells induced a strong attenuation of this strain in vivo. The adapted virus (G954-V13 differs from its parental strain by only 5 amino acids (4 in P/V/C and 1 in the M gene. While a vaccine strain, Edmonston Zagreb, could replicate equally well in various primate cells, both G954 strains exhibited restriction to the specific cell type used initially for their propagation. Surprisingly, we observed that both G954 strains induced type I IFN, the wt strain inducing even more than the attenuated ones, particularly in human plasmacytoid Dendritic Cells. Type I IFN-induced protection from the infection of both G954 strains depended on the cell type analyzed, being less efficient in the cells used to grow the viral strain. Conclusion Thus, mutations in M and P/V/C proteins can critically affect MV pathogenicity, cellular tropism and lead to virus attenuation without interfering with the α/β IFN system.

  17. Seismic motion attenuation relations in Sichuan and adjacent areas

    Institute of Scientific and Technical Information of China (English)

    LEI Jian-cheng; GAO Meng-tan; YU Yan-xiang


    The Sichuan and adjacent areas is divided into southwest China region (SWCR) and Sichuan Basin region (SCBR) according to tectonic backgrounds and seismic damage distribution features. 96 modern destructive earthquakes in SWCR and 40 in SCBR are gathered respectively. All their magnitude parameters are checked. Based on the statistic relations between epicentral intensity and magnitude as well as relation between sensible radius and magnitude, the near and far field seismic intensity attenuation features are represented and controlled. And then the seismic intensity attenuation relations along major axis, minor axis and mean axis are established separately. The systematic deviations of surface wave magnitude between China seismograph network and U.S. seismograph network are considered in this paper. By making use of the new attenuation relations of bedrock horizontal ground acceleration response spectrum in west U.S., the attenuation relations of bedrock horizontal ground acceleration response spectrum in SWCR and SCBR are digital transformed based on the attenuation model considering acceleration saturation of distance and magnitude in near field.

  18. Radar attenuation and temperature within the Greenland Ice Sheet (United States)

    MacGregor, Joseph A; Li, Jilu; Paden, John D; Catania, Ginny A; Clow, Gary D.; Fahnestock, Mark A; Gogineni, Prasad S.; Grimm, Robert E.; Morlighem, Mathieu; Nandi, Soumyaroop; Seroussi, Helene; Stillman, David E


    The flow of ice is temperature-dependent, but direct measurements of englacial temperature are sparse. The dielectric attenuation of radio waves through ice is also temperature-dependent, and radar sounding of ice sheets is sensitive to this attenuation. Here we estimate depth-averaged radar-attenuation rates within the Greenland Ice Sheet from airborne radar-sounding data and its associated radiostratigraphy. Using existing empirical relationships between temperature, chemistry, and radar attenuation, we then infer the depth-averaged englacial temperature. The dated radiostratigraphy permits a correction for the confounding effect of spatially varying ice chemistry. Where radar transects intersect boreholes, radar-inferred temperature is consistently higher than that measured directly. We attribute this discrepancy to the poorly recognized frequency dependence of the radar-attenuation rate and correct for this effect empirically, resulting in a robust relationship between radar-inferred and borehole-measured depth-averaged temperature. Radar-inferred englacial temperature is often lower than modern surface temperature and that of a steady state ice-sheet model, particularly in southern Greenland. This pattern suggests that past changes in surface boundary conditions (temperature and accumulation rate) affect the ice sheet's present temperature structure over a much larger area than previously recognized. This radar-inferred temperature structure provides a new constraint for thermomechanical models of the Greenland Ice Sheet.


    Directory of Open Access Journals (Sweden)

    K. Ferria


    Full Text Available The light intensity control of a luminous source is a very important operation in many optical applications. Several types of light attenuator exploiting different optical phenomena like diffraction, absorption, and reflection exist and they differ principally in the maximum attenuation rate, the control range, the sensitivity and the spectral band. In the presented work, we have developed and designed a light attenuator based on the progressive decrease of the transmitted light intensity, when it undergoes multiple vitreous reflections across eight plates glasses arranged in a roof shape. Several tests were carried out using a laser light as a source. We have shown that the attenuation rate can be controlled by the choice of the incidence angle on the glasses slides, in addition we have confirmed, for the case of perpendicular polarization of the laser light, that the attenuation obeys to a linear function. The obtained results are very close to those predicted theoretically.

  20. Laboratory Measurements of Velocity and Attenuation in Sediments

    Energy Technology Data Exchange (ETDEWEB)

    Zimmer, M A; Berge, P A; Bonner, B P; Prasad, M


    Laboratory measurements are required to establish relationships between the physical properties of unconsolidated sediments and P- and S-wave propagation through them. Previous work has either focused on measurements of compressional wave properties at depths greater than 500 m for oil industry applications or on measurements of dynamic shear properties at pressures corresponding to depths of less than 50 m for geotechnical applications. Therefore, the effects of lithology, fluid saturation, and compaction on impedance and P- and S-wave velocities of shallow soils are largely unknown. We describe two state-of-the-art laboratory experiments. One setup allows us to measure ultrasonic P-wave velocities at very low pressures in unconsolidated sediments (up to 0.1 MPa). The other experiment allows P- and S-wave velocity measurements at low to medium pressures (up to 20 MPa). We summarize the main velocity and attenuation results on sands and sand - clay mixtures under partially saturated and fully saturated conditions in two ranges of pressures (0 - 0.1 MPa and 0.1 - 20 MPa) representative of the top few meters and the top 1 km, respectively. Under hydrostatic pressures of 0.1 to 20 MPa, our measurements demonstrate a P- and S-wave velocity-dependence in dry sands around a fourth root (0.23 -0.26) with the pressure dependence for S-waves being slightly lower. The P- velocity-dependence in wet sands lies around 0.4. The Vp-Vs and the Qp-Qs ratios together can be useful tools to distinguish between different lithologies and between pressure and saturation effects. These experimental velocities at the frequency of measurement (200 kHz) are slightly higher that Gassmann's static result. For low pressures under uniaxial stress, Vp and Vs were a few hundred meters per second with velocities showing a strong dependence on packing, clay content, and microstructure. We provide a typical shallow soil scenario in a clean sand environment and reconstruct the velocity profile

  1. Particle Physics (United States)

    Cooper, Necia Grant; West, Geoffrey B.


    Preface; Introduction; Part I. Theoretical Framework: 1. Scale and dimension - From animals to quarks Geoffrey B. West; 2. Particle physics and the standard model Stuart Raby, Richard C. Slansky and Geoffrey B. West; QCD on a Cray: the masses of elementary particles Gerald Guralnik, Tony Warnock and Charles Zemach; Lecture Notes - From simple field theories to the standard model; 3. Toward a unified theory: an essay on the role of supergravity in the search for unification Richard C. Slansky; 4. Supersymmetry at 100 GeV Stuart Raby; 5. The family problem T. Goldman and Michael Martin Nieto; Part II. Experimental Developments: 6. Experiments to test unification schemes Gary H. Sanders; 7. The march toward higher energies S. Peter Rosen; LAMPF II and the High-Intensity Frontier Henry A. Thiessen; The SSC - An engineering challenge Mahlon T. Wilson; 8. Science underground - the search for rare events L. M. Simmons, Jr; Part III. Personal Perspectives: 9. Quarks and quirks among friends Peter A. Carruthers, Stuart Raby, Richard C. Slansky, Geoffrey B. West and George Zweig; Index.

  2. [Physical therapy]. (United States)

    Chohnabayashi, Naohiko


    Recently, pulmonary rehabilitation program is widely considered one of the most effective and evidence-based treatment for not only chronic obstructive pulmonary disease (COPD) but many clinical situations including neuro-muscular disease, post-operative status and weaning period from the ventilator, etc. The essential components of a pulmonary rehabilitation program are team assessment, patient training, psycho-social intervention, exercise, and follow-up. In 2003, Japanese medical societies (J. Thoracic Society, J. Pul. Rehabilitation Society and J. Physiotherapist Society) made a new guideline for pulmonary rehabilitation, especially how to aproach the execise training. As for the duration after surgical operation, airway cleaning is the important technique to prevent post-operative complications including pneumonia. Postural dranage technique is well known for such condition, at the same time, several instruments (flutter vulve, positive expiratory mask, high frequecy oscillation, etc) were also used for the patient to expectrate airway mucus easier. Lung transplantation is a new method of treatment for the critically-ill patients with chronic respiratoy failure. Several techniques of physical therapy are must be needed before and after lung transplantation to prevent both pulmonary infection and osteoporosis.

  3. Antineutron physics

    CERN Document Server

    Bressani, Tullio


    Antineutrons ($\\overline{n}$'s) have been used only in the last few years as projectiles for nuclear and particle physics experiments, mainly in the low momentum region. The reason is that, in spite of some undoubted advantages (absence of Coulomb corrections, pure I=1 state for the ($\\overline{n}p$) system), the difficulties in obtaining beams of $\\overline{n}$'s of suitable intensity and energy definition were overwhelming. The setting-up of suitable beams at BNL and mainly at CERN LEAR (with momentum lower than 400 MeV/c) allowed a first round of interesting experiments. In this review a summary of the most important experimental issues obtained in this field will be presented. They range from studies on the antineutron annihilation dynamics, intended to shed light on the mechanisms responsible for the particles production as well as for the possible formation of quasinuclear nucleon-antinucleon bound states, to meson spectroscopy researches, aiming to identify the existence of new, possibly exotic, resona...

  4. Polymer physics

    CERN Document Server

    Gedde, Ulf W


    This book is the result of my teaching efforts during the last ten years at the Royal Institute of Technology. The purpose is to present the subject of polymer physics for undergraduate and graduate students, to focus the fundamental aspects of the subject and to show the link between experiments and theory. The intention is not to present a compilation of the currently available literature on the subject. Very few reference citations have thus been made. Each chapter has essentially the same structure: starling with an introduction, continuing with the actual subject, summarizing the chapter in 30D-500 words, and finally presenting problems and a list of relevant references for the reader. The solutions to the problems presented in Chapters 1-12 are given in Chapter 13. The theme of the book is essentially polymer science, with the exclusion of that part dealing directly with chemical reactions. The fundamentals in polymer science, including some basic polymer chemistry, are presented as an introduction in t...

  5. Physics-10 (United States)

    Marinciuc, Mihai; Rusu, Spiridon

    The textbook is designated for the 10-th class of real and humanitarian lyceums, according the curriculum of the Ministry of Education of the Republic of Moldova for lyceums. It encomprises mechanics in 5 chapters (Kynematics (Trajectory, Relativity of the Motion, Circular Motion and other); Dynamics and the Forces in Nature (The mass and Force, Universal attraction, Elastic Forces, Friction, The motion of the Bodies under the action of many forces, The relativity Principle of Galilei and other); Statics; Mechanical Impuls and its conservation; Mechanical work and Mechanical Energy and its conservation( Mechanical work and Power, Kynetic Energy, The mechanical work of the Elastic Force, The conservation laws) and Molecular Physics and Thermdynamics in 5 chapters (The structure of the Matter; Gases and their properties (Simplest transformations, The molecular-kynetic theory, Real gases) ; Solids and Liquids (The Hook's law, Superficial tension, Dilatation and other); Phase transitions (including sublimation); (Calorimetry; Thermal machines; The second law of thermodynamics and other). The textbook includes also 8 laboratory (experimental) works, a number of questions for control and a number of 300 problems, half of which have answers. Short biographies of about 15 physicists are included. The textbook is illustrated with diagrames, paintings and portrets in black and white.

  6. Diffractive Physics

    CERN Document Server

    Martin, A D; Khoze, V A; Krauss, F; Ryskin, M G; Zapp, K


    `Soft' high-energy interactions are clearly important in pp collisions. Indeed, these events are dominant by many orders of magnitude, and about 40% are of diffractive origin; that is, due to elastic scattering or proton dissociation. Moreover, soft interactions unavoidably give an underlying component to the rare `hard' events, from which we hope to extract new physics. Here, we discuss how to quantify this contamination. First we present a brief introduction to diffraction. We emphasize the different treatment required for proton dissociation into low- and high-mass systems; the former requiring a multichannel eikonal approach, and the latter the computation of triple-Pomeron diagrams with multi-Pomeron corrections. Then we give an overview of the Pomeron, and explain how the QCD (BFKL-type) Pomeron is the natural object to continue from the `hard' to the `soft' domain. In this way we can obtain a partonic description of soft interactions. We introduce the so-called KMR model, based on this partonic approac...

  7. Neutrino Physics (United States)

    Bergström, L.; Hulth, P. O.; Botner, O.; Carlson, P.; Ohlsson, T.


    J. N. Bahcall (1934-2005) -- Preface -- List of participants -- Committees -- Nobel symposium on neutrino physics - program -- The history of neutrino oscillations / S. M. Bilenky -- Super-Kamiokande results on neutrino oscillations / Y. Suzuki -- Sudbury neutrino observatory results / A. B. McDonald -- Results from KamLAND reactor neutrino detection / A. Suzuki -- New opportunities for surprise / J. Conrad -- Solar models and solar neutrinos / J. N. Bahcall -- Atmospheric neutrino fluxes / T. K. Gaisser -- The MSW effect and matter effects in neutrino oscillations / A. Yu. Smirnov -- Three-flavour effects and CP- and T-violation in neutrino oscillations / E. Kh. Akhmedov -- Global analysis of neutrino data / M. C. Gonzalez-Garcia -- Future precision neutrino oscillation experiments and theoretical implications / M. Lindner -- Experimental prospects of neutrinoless double beta decay / E. Fiorini -- Theoretical prospects of neutrinoless double beta decay / S. T. Petcov -- Supernova neutrino oscillations / G. G. Raffelt -- High-energy neutrino astronomy / F. Halzen -- Neutrino astrophysics in the cold: Amanda, Baikal and IceCube / C. Spiering -- Status of radio and acoustic detection of ultra-high energy cosmic neutrinos and a proposal on reporting results / D. Saltzberg -- Detection of neutrino-induced air showers / A. A. Watson -- Prospect for relic neutrino searches / G. B. Gelmini -- Leptogenesis in the early universe / T. Yanagida -- Neutrinos and big bang nucleosynthesis / G. Steigman -- Extra galactic sources of high energy neutrinos / E. Waxman -- Cosmological neutrino bounds for non-cosmologists / M. Tegmark -- Neutrino intrinsic properties: the neutrino-antineutrino relation / B. Kayser -- NuTeV and neutrino properties / M. H. Shaevitz -- Absolute masses of neutrinos - experimental results and future possibilities / C. Weinheimer -- Flavor theories and neutrino masses / P. Ramond -- Neutrino mass models and leptogenesis / S. F. King -- Neutrino mass and

  8. Consideration of natural attenuation. In remedation contaminated sites

    Energy Technology Data Exchange (ETDEWEB)



    Upon the proposal submitted by ist Standing committee 5 (Contaminated Sites Committee - ALA) the Federal / State Working Group on Soil protection employed an ad hoc subcommittee dealing with considering natural attenuation in remediating contaminated sites and preparing an inter-State position paper. In the present position paper the way how to consider natural attenuation in practical remediation of contaminated sites is described. The systematic approach outlined allows an understandable decision-finding. A way is shown how the competent soil protection authorities may exercise discretion and in the framework of checking the appropriateness of measures may decide on the implementation of MNA based on a MNA concept (MNA = monitored natural attenuation). It is, however, also explained that when carrying out MNA a decision always made in an individual case is concerned which should be made in a close agreement between the obligated party and the authority.

  9. Smart structures for shock wave attenuation using ER inserts (United States)

    Kim, Jaehwan; Kim, Jung-Yup; Choi, Seung-Bok; Kim, Kyung-Su


    This Paper demonstrates the possibility of shock wave attenuation propagating through a smart structure that incorporates ER insert. The wave transmission of ER inserted beam is theoretically derived using Mead & Markus model and the theoretical results are compared with the finite element analysis results. To experimentally verify the shock wave attenuation, ER insert in an aluminum plate is made and two piezoceramic disks are used as transmitter and receiver of the wave. The transmitter sends a sine pulse signal such that a component of shock wave travels through the plate structure and the receiver gets the transmitted wave signal. Wave propagation of the ER insert can be adjusted by changing the applied electric field on the ER insert. Details of the experiment are addressed and the possibility of shock wave attenuation is experimentally verified. This kind of smart structure can be used for warship and submarine hull structures to protect fragile and important equipment.

  10. Broadband fractal acoustic metamaterials for low-frequency sound attenuation (United States)

    Song, Gang Yong; Cheng, Qiang; Huang, Bei; Dong, Hui Yuan; Cui, Tie Jun


    We fabricate and experimentally characterize a broadband fractal acoustic metamaterial that can serve to attenuate the low-frequency sounds at selective frequencies ranging from 225 to 1175 Hz. The proposed metamaterials are constructed by the periodic Hilbert fractal elements made of photosensitive resin via 3D printing. In analogy to electromagnetic fractal structures, it is shown that multiple resonances can also be excited in the acoustic counterpart due to their self-similar properties, which help to attenuate the acoustic energy in a wide spectrum. The confinement of sound waves in such subwavelength element is evidenced by both numerical and experimental results. The proposed metamaterial may provide possible alternative for various applications such as the noise attenuation and the anechoic materials.

  11. Fiber movements and sound attenuation in glass wool

    DEFF Research Database (Denmark)

    Tarnow, Viggo


    Propagation of a plane harmonic sound wave in fiber materials such as glass wool is studied theoretically and experimentally. Wave equations are set up that take into account the movement of the fiber skeleton. The attenuation of the sound wave in slabs of glass wool was calculated and measured....... The main new result is that the experimental attenuation at low-frequency propagating wave is lower when the fibers move. For wave with frequency 100 Hz in glass wool of density 20 kg/m3, the attenuation of a layer of thickness 0.20 m is 4 dB if the fibers move, and 12 dB if they do not move...

  12. Correction for hydrometeor attenuation of C band radar data

    Institute of Scientific and Technical Information of China (English)


    C band digital weather radar observed data, collected from the Huaihe River Basin Energy and Water Cycle Experiment (HUBEX), are used for the study of correction of hydrometeor attenuation in the Fuyang region. An iterative algorithm is used for the correction scheme. The preliminary study shows that there may be a big difference between the radar observed reflectivity and the corresponding corrected one. Based upon the hourly precipitation data derived by the radar data sampled from the observations at intervals of 10 min and rain-gauge-recorded hourly precipitation data, it is found that the attenuation correction algorithm gives better results than those from the direct observation. It is also shown that the temperature of hydrometeors may strongly affect the results derived from the attenuation algorithm.

  13. Monte Carlo simulation of laser attenuation characteristics in fog (United States)

    Wang, Hong-Xia; Sun, Chao; Zhu, You-zhang; Sun, Hong-hui; Li, Pan-shi


    Based on the Mie scattering theory and the gamma size distribution model, the scattering extinction parameter of spherical fog-drop is calculated. For the transmission attenuation of the laser in the fog, a Monte Carlo simulation model is established, and the impact of attenuation ratio on visibility and field angle is computed and analysed using the program developed by MATLAB language. The results of the Monte Carlo method in this paper are compared with the results of single scattering method. The results show that the influence of multiple scattering need to be considered when the visibility is low, and single scattering calculations have larger errors. The phenomenon of multiple scattering can be interpreted more better when the Monte Carlo is used to calculate the attenuation ratio of the laser transmitting in the fog.

  14. Long term attenuation measurements on optical ground wires

    Energy Technology Data Exchange (ETDEWEB)

    Lamarche, L.; Gagnon, D.; Miron, M. [Hydro-Quebec, Varennes, Quebec1 (Canada)


    The attenuation stability of optical fibers integrated in optical ground wires (OPGW) cables over temperature and time is of paramount importance in the planning of long distance links. The authors report here a mean thermal attenuation dependence of 5.5{center_dot}10{sup {minus}5} dB/(km{center_dot}C) at 1,550 nm, on a 220 km span of dispersion shifted (DS) fibers of an installed OPGW cable. This optical link is installed in the James Bay region over a 735 kV power line where temperature varies from {minus}40 C to +30 C annually. The data sample presented covers 1.5 year starting December 1993. The data sample presented covers 1.5 year starting December 1993. During that period, the authors also observed a temporal evolution of the attenuation described by the empirical relation A = A{sub 0} (t{minus}t{sub 0}){sup 0.00394}.

  15. Ultrasonic attenuation of CdSe at low temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, B.J., E-mail: braulio@ula.v [Centro de Estudios de Semiconductores, Departamento de Fisica, Facultad de Ciencias, Universidad de Los Andes Apartado de Correos No.1, La Hechicera, Merida 5251 (Venezuela, Bolivarian Republic of); Calderon, E.; Bracho, D.B. [Centro de Estudios de Semiconductores, Departamento de Fisica, Facultad de Ciencias, Universidad de Los Andes Apartado de Correos No.1, La Hechicera, Merida 5251 (Venezuela, Bolivarian Republic of); Perez, J.F. [Laboratorio de Instrumentacion Cientifica, Facultad de Ciencias, Universidad de Los Andes Apartado de Correos No.1, La Hechicera, Merida 5251 (Venezuela, Bolivarian Republic of)


    The ultrasonic attenuation of a single crystal of CdSe has been investigated over the temperature range from 1.2 to 300 K at frequencies of 10, 30 and 90 MHz. We report here the temperature dependence of the attenuation in the range 1.2-30 K for piezoactive and non-piezoactive acoustic waves. A temperature-induced relaxation for two piezoactive waves, which scale with frequency towards higher temperatures, was found. A modified Hutson and White model with a new parameter {gamma} is proposed to explain the relaxation maxima of our data and others in the literature. In this model the parameter {gamma}, which seems to be closely related to the compensation, takes into account the impurities-sound wave piezoelectric coupling. By inverting the proposed expression for the sound attenuation to obtain the electrical conductivity from the relaxation, it is found that impurity conductivity of the hopping type is the dominant conduction process at low temperatures.

  16. Physical Therapy (For Parents) (United States)

    ... trauma head injury limb deficiencies muscle diseases What Physical Therapists Do Physical therapists use a variety of treatments ... is safe What to Look for in a Physical Therapist Entry-level physical therapists must receive a doctoral ...

  17. Aerobic exercise attenuates inhibitory avoidance memory deficit induced by paradoxical sleep deprivation in rats. (United States)

    Fernandes, Jansen; Baliego, Luiz Guilherme Zaccaro; Peixinho-Pena, Luiz Fernando; de Almeida, Alexandre Aparecido; Venancio, Daniel Paulino; Scorza, Fulvio Alexandre; de Mello, Marco Tulio; Arida, Ricardo Mario


    The deleterious effects of paradoxical sleep deprivation (SD) on memory processes are well documented. Physical exercise improves many aspects of brain functions and induces neuroprotection. In the present study, we investigated the influence of 4 weeks of treadmill aerobic exercise on both long-term memory and the expression of synaptic proteins (GAP-43, synapsin I, synaptophysin, and PSD-95) in normal and sleep-deprived rats. Adult Wistar rats were subjected to 4 weeks of treadmill exercise training for 35 min, five times per week. Twenty-four hours after the last exercise session, the rats were sleep-deprived for 96 h using the modified multiple platform method. To assess memory after SD, all animals underwent training for the inhibitory avoidance task and were tested 24h later. The aerobic exercise attenuated the long-term memory deficit induced by 96 h of paradoxical SD. Western blot analysis of the hippocampus revealed increased levels of GAP-43 in exercised rats. However, the expression of synapsin I, synaptophysin, and PSD-95 was not modified by either exercise or SD. Our results suggest that an aerobic exercise program can attenuate the deleterious effects of SD on long-term memory and that this effect is not directly related to changes in the expression of the pre- and post-synaptic proteins analyzed in the study.

  18. High-resolution gamma ray attenuation density measurements on mining exploration drill cores, including cut cores (United States)

    Ross, P.-S.; Bourke, A.


    Physical property measurements are increasingly important in mining exploration. For density determinations on rocks, one method applicable on exploration drill cores relies on gamma ray attenuation. This non-destructive method is ideal because each measurement takes only 10 s, making it suitable for high-resolution logging. However calibration has been problematic. In this paper we present new empirical, site-specific correction equations for whole NQ and BQ cores. The corrections force back the gamma densities to the "true" values established by the immersion method. For the NQ core caliber, the density range extends to high values (massive pyrite, 5 g/cm3) and the correction is thought to be very robust. We also present additional empirical correction factors for cut cores which take into account the missing material. These "cut core correction factors", which are not site-specific, were established by making gamma density measurements on truncated aluminum cylinders of various residual thicknesses. Finally we show two examples of application for the Abitibi Greenstone Belt in Canada. The gamma ray attenuation measurement system is part of a multi-sensor core logger which also determines magnetic susceptibility, geochemistry and mineralogy on rock cores, and performs line-scan imaging.

  19. Virological and phylogenetic characterization of attenuated small ruminant lentivirus isolates eluding efficient serological detection. (United States)

    Cardinaux, Laure; Zahno, Marie-Luise; Deubelbeiss, Martina; Zanoni, Reto; Vogt, Hans-Rudolf; Bertoni, Giuseppe


    Three field isolates of small ruminant lentiviruses (SRLVs) were derived from a mixed flock of goats and sheep certified for many years as free of caprine arthritis encephalitis virus (CAEV). The phylogenetic analysis of pol sequences permitted to classify these isolates as A4 subtype. None of the animals showed clinical signs of SRLV infection, confirming previous observations which had suggested that this particular subtype is highly attenuated, at least for goats. A quantitative real time PCR strategy based on primers and probes derived from a highly variable env region permitted us to classify the animals as uninfected, singly or doubly infected. The performance of different serological tools based on this classification revealed their profound inadequacy in monitoring animals infected with this particular SRLV subtype. In vitro, the isolates showed differences in their cytopathicity and a tendency to replicate more efficiently in goat than sheep cells, especially in goat macrophages. By contrast, in vivo, these viruses reached significantly higher viral loads in sheep than in goats. Both env subtypes infected goats and sheep with equal efficiency. One of these, however, reached significantly higher viral loads in both species. In conclusion, we characterized three isolates of the SRLV subtype A4 that efficiently circulate in a mixed herd of goats and sheep in spite of their apparent attenuation and a strict physical separation between goats and sheep. The poor performance of the serological tools applied indicates that, to support an SRLV eradication campaign, it is imperative to develop novel, subtype specific tools.

  20. Homogeneous Magnetic Field Source For Attenuated Total Reflection

    Directory of Open Access Journals (Sweden)

    Lesňák Michal


    Full Text Available The paper is focused on the study of two-dimensional magnetic field distribution used for an analysis of samples containing magnetically active films by means of the Attenuated Total Reflection (ATR method. The design of a proposed electromagnet and the magnetic field model computation are presented together with the results obtained from magnetic field distribution measurement. The ATR method can provide information about a thin film thickness, refractive index, and attenuation in addition to the perfunctory coupling of an optical wave into and off a waveguide [1, 2]. The prism coupling conditions are determined for magnetic structures with induced anisotropy.

  1. Sound attenuation using microelectromechanical systems fabricated acoustic metamaterials (United States)

    Yunker, William N.; Stevens, Colin B.; Flowers, George T.; Dean, Robert N.


    Unlike traditional rotational gyroscopes, microelectromechanical systems (MEMS) gyroscopes use a vibrating proof mass rather than a rotational mass to sense changes in angular rate. They are also smaller and less expensive than traditional gyroscopes. MEMS gyroscopes are known to be susceptible to the effects of acoustic noise, in particular high frequency and high power acoustic noise. Most notably, this has been proven true in aerospace applications where the noise can reach levels in excess of 120 dB and the noise frequency can exceed 20 kHz. The typical resonant frequency for the proof mass of a MEMS gyroscope is between 3 and 20 kHz. High power, high frequency acoustic noise can disrupt the output signal of the gyroscope to the point that the output becomes unreliable. In recent years, considerable research has focused on the fascinating properties found in metamaterials. A metamaterial is an artificially fabricated device or structure that is engineered to produce desired material responses that can either mimic known behaviors or produce responses that do not occur naturally in materials found in nature. Acoustic metamaterials, in particular, have shown great promise in the field of sound attenuation. This paper proposes a method to mitigate the performance degradation of the MEMS gyroscope in the presence of high power, high frequency acoustic noise by using a new acoustic metamaterial in the form of a two-dimensional array of micromachined Helmholtz resonators. The Helmholtz resonators are fabricated in a silicon wafer using standard MEMS manufacturing techniques and are designed to attenuate sound at the resonant frequency of the gyroscope proof mass. The resonator arrays were diced from the silicon wafer in one inch squares and assembled into a box open on one end in a manner to attenuate sound on all sides of the gyroscope, and to seal the gyroscope inside the box. The resulting acoustic metamaterial device was evaluated in an acoustic chamber and was

  2. Heat radiative characteristics of ultra-attenuated materials

    Institute of Scientific and Technical Information of China (English)

    Dehong Xia; Yonghong Wu


    From the microstructure of heat radiation, the interaction between the incident heat radiative wave and the electromagnetism syntonic wave is analyzed to reveal the emission, absorption, transmission and reflection mechanisms of the incident heat radiative wave in materials. Based on Lorentz dispersion theory, the effect of optical parameters on heat radiative characteristics is also analyzed. The method of ultra-attenuation and nanocrystallization improving the heat radiative characteristics of the material and the emissivity dispersion of the ultra-attenuated materials are brought to light.

  3. Attenuating water hammer pressure by means of gas storage tank

    Institute of Scientific and Technical Information of China (English)


    The basic equations for computing the volume of gas storage tank were derived from the principles of attenuating water hammer pressure. Verifications using experiments indicate that the proposed equation can provide a fare precision in the predictions. By using the model of solid-liquid two-phase flow, the gas storage tank, pressure-relief valves and slow-closure reverse-control valves were compared with practical engineering problems, and the functions of gas storage tank in attenuating water hammer pressure were further investigated.

  4. Continental Fog Attenuation Empirical Relationship from Measured Visibility Data

    Directory of Open Access Journals (Sweden)

    F. Nadeem


    Full Text Available Free Space Optics (FSO has the great potential for future communication applications. However, weather influenced reduced availability had been the main cause for its restricted growth. Among different weather influences fog plays the major role. A new model generalized for all FSO wavelengths, has been proposed for the prediction of continental fog attenuation using visibility data. The performance of the proposed model has been compared with well known models for measured attenuation data of Continental fog. The comparison has been performed in terms of Root Mean Square Error (RMSE.

  5. Repetitive cryotherapy attenuates the in vitro and in vivo mononuclear cell activation response. (United States)

    Lindsay, Angus; Othman, Mohd Izani; Prebble, Hannah; Davies, Sian; Gieseg, Steven P


    What is the central question of this study? Acute and repetitive cryotherapy are routinely used to accelerate postexercise recovery, although the effect on resident immune cells and repetitive exposure has largely been unexplored and neglected. What is the main finding and its importance? Using blood-derived mononuclear cells and semi-professional mixed martial artists, we show that acute and repetitive cryotherapy reduces the in vitro and in vivo T-cell and monocyte activation response whilst remaining independent of the physical performance of elite athletes. We investigated the effect of repetitive cryotherapy on the in vitro (cold exposure) and in vivo (cold water immersion) activation of blood-derived mononuclear cells following high-intensity exercise. Single and repeated cold exposure (5°C) of a mixed cell culture (T cells and monocytes) was investigated using in vitro tissue culture experimentation for total neopterin production (neopterin plus 7,8-dihydroneopterin). Fourteen elite mixed martial art fighters were also randomly assigned to either a cold water immersion (15 min at 10°C) or passive recovery protocol, which they completed three times per week during a 6 week training camp. Urine was collected and analysed for neopterin and total neopterin three times per week, and perceived soreness, fatigue, physical performance (broad jump, push-ups and pull-ups) and training performance were also assessed. Single and repetitive cold exposure significantly (P < 0.001) reduced total neopterin production from the mixed cell culture, whereas cold water immersion significantly (P < 0.05) attenuated urinary neopterin and total neopterin during the training camp without having any effect on physical performance parameters. Soreness and fatigue showed little variation between the groups, whereas training session performance was significantly (P < 0.05) elevated in the cold water immersion group. The data suggest that acute and repetitive cryotherapy

  6. Research on attenuation characteristic of sound wave in coal or rock body

    Institute of Scientific and Technical Information of China (English)

    NIE Bai-sheng; HE Xue-qiu; LI Xiang-chun; GAO Hong


    In order to using power sound wave increase permeability of coal, rules of attenuation of sound wave in coal should be studied. In this paper, characteristic and mechanism of attenuation of sound wave in coal was researched according to acoustic theory and attenuation coefficients was estimated by acoustic parameter of coal. The research results show that the main attenuation mechanism of sound wave in coal is absorption attenuation and scattering attenuation. The absorption attenuation includes viscous absorption, thermal conduction absorption and relaxation absorption. Attenuation coefficient of sound wave in gaseous coal is 38.5 Np/m. Researches on attenuation characteristic of sound wave will provide the theoretical basis for power sound wave improving permeability of coal and accelerating desorption of coal bed gas.

  7. Nonlinear manipulation of tunable microwave amplification and attenuation in superconducting circuits (United States)

    Li, Hai-Chao; Zhang, Hai-Yang; He, Qing; Ge, Guo-Qin


    We demonstrate the controllable nonlinear microwave modulation in a cyclically driven three-level superconducting Josephson system. By designing two subtle matched conditions in the △-type atom-field configuration, a new physical mechanism - combined action of nonlinear wave mixing and wave interference - is developed and leads to not only amplification but also attenuation for two microwave signals. Our results show that such a nonlinear manipulation of the signal transition from enhancement to damping can be tuned in a large scope by controlling the relative phase and the driving-field frequency and thus the solid-state Josephson system can act as a phase- and frequency-controlled amplitude modulator. Our study opens up a fascinating perspective for its widespread applications in nonlinear optics and quantum information science.

  8. A CMOS Wideband Linear Current Attenuator with Electronically Variable Gain

    NARCIS (Netherlands)

    Wiegerink, Remco J.


    A CMOS highly linear current attenuator is described. The circuit is suited for both differential and single input currents. The current gain is electronically variable between -1 and +1 by means of two controlling currents. A simple additional circuit is described to obtain a gain that is linearly

  9. Low-energy gamma ray attenuation characteristics of aviation fuels (United States)

    Singh, Jag J.; Shen, Chih-Ping; Sprinkle, Danny R.


    Am241 (59.5 keV) gamma ray attenuation characteristics were investigated in 270 aviation fuel (Jet A and Jet A-1) samples from 76 airports around the world as a part of world wide study to measure the variability of aviation fuel properties as a function of season and geographical origin. All measurements were made at room temperature which varied from 20 to 27 C. Fuel densities (rho) were measured concurrently with their linear attenuation coefficients (mu), thus providing a measure of mass attenuation coefficient (mu/rho) for the test samples. In 43 fuel samples, rho and mu values were measured at more than one room temperature, thus providing mu/rho values for them at several temperatures. The results were found to be independent of the temperature at which mu and rho values were measured. It is noted that whereas the individual mu and rho values vary considerably from airport to airport as well as season to season, the mu/rho values for all samples are constant at 0.1843 + or - 0.0013 cu cm/gm. This constancy of mu/rho value for aviation fuels is significant since a nuclear fuel quantity gauging system based on low energy gamma ray attenuation will be viable throughout the world.

  10. Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias

    DEFF Research Database (Denmark)

    Collis, C S; Rice-Evans, C; Davies, Michael Jonathan


    The novel monohydroxamates N-methyl hexanoylhydroxamic acid, N-methyl acetohydroxamic acid, and N-methyl butyrohydroxamic acid have antioxidant and iron chelating properties. They attenuated reperfusion-induced contractile dysfunction following long periods of ischaemia (50 min) in the isolated r...

  11. On the effectiveness of mangroves in attenuating cyclone induced waves

    NARCIS (Netherlands)

    Narayan, S.; Suzuki, T.; Stive, M.J.F.; Verhagen, H.J.; Ursem, W.N.J.; Ranasinghe, R.


    A study of the effectiveness of mangroves in attenuating cyclone- induced waves was done using the SWAN 40.81 numerical model. Hydraulic parameters during extreme events and local mangrove vegetation parameters were estimated for the Kanika Sands mangrove island near the upcoming Dhamra Port in Oris

  12. Measurement of acoustic attenuation in South Pole ice

    NARCIS (Netherlands)

    Abbasi, R.; Abdou, Y.; Abu-Zayyad, T.; Adams, J.; Aguilar, J.A.; Ahlers, M.; Andeen, K.; Auffenberg, J.; Bai, X.; Baker, M.; Barwick, S.W.; Bay, R.; Alba, J.L.B.; Beattie, K.; Beatty, J.J.; Bechet, S.; Becker, J.K.; Becker, K.H.; Benabderrahmane, M.L.; Berdermann, J.; Berghaus, P.; Berley, D.; Bernardini, E.; Bertrand, D.; Besson, D.Z.; Bissok, M.; Blaufuss, E.; Boersma, D.J.; Bohm, C.; Boser, S.; Botner, O.; Bradley, L.; Braun, J.; Buitink, S.; Carson, M.; Chirkin, D.; Christy, B.; Clem, J.; Clevermann, F.; Cohen, S.; Colnard, C.; Cowen, D.F.; D'Agostino, M.V.; Danninger, M.; Clercq, C. De; Demirors, L.; Depaepe, O.; Descamps, F.; Desiati, P.; Vries-Uiterweerd, G. de; DeYoung, T.; Diaz-Velez, J.C.; Dreyer, J.; Dumm, J.P.; Duvoort, M.R.; Ehrlich, R.; Eisch, J.; Ellsworth, R.W.; Engdegard, O.; Euler, S.; Evenson, P.A.; Fadiran, O.; Fazely, A.R.; Feusels, T.; Filimonov, K.; Finley, C.; Foerster, M.M.; Fox, B.D.; Franckowiak, A.; Franke, R.; Gaisser, T.K.; Gallagher, J.; Ganugapati, R.; Geisler, M.; Gerhardt, L.; Gladstone, L.; Glusenkamp, T.; Goldschmidt, A.; Goodman, J.A.; Grant, D.; Griesel, T.; Gross, A.; Grullon, S.; Gunasingha, R.M.; Gurtner, M.; Gustafsson, L.; Ha, C.; Hallgren, A.; Halzen, F.; Han, K.; Hanson, K.; Helbing, K.; Herquet, P.; Hickford, S.; Hill, G.C.; Hoffman, K.D.; Homeier, A.; Hoshina, K.; Hubert, D.; Huelsnitz, W.; Lafebre, S.J.


    Using the South Pole Acoustic Test Setup (SPATS) and a retrievable transmitter deployed in holes drilled for the IceCube experiment, we have measured the attenuation of acoustic signals by South Pole ice at depths between 190 m and 500 m. Three data sets, using different acoustic sources, have been

  13. Outdoor FSO Communications Under Fog: Attenuation Modeling and Performance Evaluation

    KAUST Repository

    Esmail, Maged Abdullah


    Fog is considered to be a primary challenge for free space optics (FSO) systems. It may cause attenuation that is up to hundreds of decibels per kilometer. Hence, accurate modeling of fog attenuation will help telecommunication operators to engineer and appropriately manage their networks. In this paper, we examine fog measurement data coming from several locations in Europe and the United States and derive a unified channel attenuation model. Compared with existing attenuation models, our proposed model achieves a minimum of 9 dB, which is lower than the average root-mean-square error (RMSE). Moreover, we have investigated the statistical behavior of the channel and developed a probabilistic model under stochastic fog conditions. Furthermore, we studied the performance of the FSO system addressing various performance metrics, including signal-to-noise ratio (SNR), bit-error rate (BER), and channel capacity. Our results show that in communication environments with frequent fog, FSO is typically a short-range data transmission technology. Therefore, FSO will have its preferred market segment in future wireless fifth-generation/sixth-generation (5G/6G) networks having cell sizes that are lower than a 1-km diameter. Moreover, the results of our modeling and analysis can be applied in determining the switching/thresholding conditions in highly reliable hybrid FSO/radio-frequency (RF) networks.

  14. Attenuation of Rayleigh Surface Waves in a Porous Material

    Institute of Scientific and Technical Information of China (English)



    Using acoustic microscopy at higher frequency,we show the velocity evolutions of surface acoustic waves,in particular Rayleigh waves that depend on porosity for a mesoporous silicon layer.The velocities are obtained from different V(z) curves,which are determined experimentally at a frequency of 600MHz.The analysis of V(z) data yields attenuation that is directly dependent on porosity.On the other hand,αN attenuation has been modeled and allows us to investigate its influence on the velocity VR of the propagation for Rayleigh waves.%Using acoustic microscopy at higher frequency, we show the velocity evolutions of surface acoustic waves, in particular Rayleigh waves that depend on porosity for a mesoporous silicon layer. The velocities are obtained from different V(z) curves, which are determined experimentally at a frequency of 600 MHz. The analysis of V(z) data yields attenuation that is directly dependent on porosity. On the other hand, αN attenuation has been modeled and allows us to investigate its influence on the velocity VR of the propagation for Rayleigh waves.

  15. Simultaneous amplification and attenuation in isotropic chiral materials

    CERN Document Server

    Mackay, Tom G


    The electromagnetic field phasors in an isotropic chiral material (ICM) are superpositions of two Beltrami fields of different handedness. Application of the Bruggeman homogenization formalism to two-component composite materials delivers ICMs wherein Beltrami fields of one handedness attenuate whereas Beltrami waves of the other handedness amplify. One component material is a dissipative ICM, the other an active dielectric material.

  16. Closed-Loop Control of MEMS Variable Optical Attenuator (VOA)

    Institute of Scientific and Technical Information of China (English)

    H.Cai; X.; M.; Zhang; A.; Q.; Liu; Y.; X.; Wang; C.; Lu


    This paper reports the development of an optical power regulator based on surface-micromachined variable optical attenuators (VOAs). By use of closed-loop control circuits, each VOA module implements the functions of power setpoint tracking, disturbance rejection and ripple suppression.

  17. Gamma ray attenuation coefficient measurement for neutron-absorbent materials

    Energy Technology Data Exchange (ETDEWEB)

    Jalali, Majid [Isfahan Nuclear Science and Technology Research Institute (NSTRT), Reactor and Accelerators Research and Development School, Atomic Energy Organization (Iran, Islamic Republic of)], E-mail:; Mohammadi, Ali [Faculty of Science, Department of Physics, University of Kashan, Km. 6, Ravand Road, Kashan (Iran, Islamic Republic of)


    The compounds Na{sub 2}B{sub 4}O{sub 7}, H{sub 3}BO{sub 3}, CdCl{sub 2} and NaCl and their solutions attenuate gamma rays in addition to neutron absorption. These compounds are widely used in the shielding of neutron sources, reactor control and neutron converters. Mass attenuation coefficients of gamma related to the four compounds aforementioned, in energies 662, 778.9, 867.38, 964.1, 1085.9, 1173, 1212.9, 1299.1,1332 and 1408 keV, have been determined by the {gamma} rays transmission method in a good geometry setup; also, these coefficients were calculated by MCNP code. A comparison between experiments, simulations and Xcom code has shown that the study has potential application for determining the attenuation coefficient of various compound materials. Experiment and computation show that H{sub 3}BO{sub 3} with the lowest average Z has the highest gamma ray attenuation coefficient among the aforementioned compounds.

  18. Engineering attenuated virulence of a Theileria annulata-infected macrophage.

    Directory of Open Access Journals (Sweden)

    Nadia Echebli

    Full Text Available Live attenuated vaccines are used to combat tropical theileriosis in North Africa, the Middle East, India, and China. The attenuation process is empirical and occurs only after many months, sometimes years, of in vitro culture of virulent clinical isolates. During this extensive culturing, attenuated lines lose their vaccine potential. To circumvent this we engineered the rapid ablation of the host cell transcription factor c-Jun, and within only 3 weeks the line engineered for loss of c-Jun activation displayed in vitro correlates of attenuation such as loss of adhesion, reduced MMP9 gelatinase activity, and diminished capacity to traverse Matrigel. Specific ablation of a single infected host cell virulence trait (c-Jun induced a complete failure of Theileria annulata-transformed macrophages to disseminate, whereas virulent macrophages disseminated to the kidneys, spleen, and lungs of Rag2/γC mice. Thus, in this heterologous mouse model loss of c-Jun expression led to ablation of dissemination of T. annulata-infected and transformed macrophages. The generation of Theileria-infected macrophages genetically engineered for ablation of a specific host cell virulence trait now makes possible experimental vaccination of calves to address how loss of macrophage dissemination impacts the disease pathology of tropical theileriosis.

  19. Variable optical attenuator fabricated by direct UV writing

    DEFF Research Database (Denmark)

    Svalgaard, Mikael; Færch, Kjartan Ullitz; Andersen, L.U.


    It is demonstrated that direct ultraviolet writing of waveguides is a method suitable for mass production of compact variable optical attenuators with low insertion loss, low polarization-dependent loss, and high dynamic range. The fabrication setup is shown to be robust, providing good device...

  20. PAUT inspection of copper canister: Structural attenuation and POD formulation (United States)

    Gianneo, A.; Carboni, M.; Mueller, C.; Ronneteg, U.


    For inspection of thick-walled (50mm) copper canisters for final disposal of spent nuclear fuel in Sweden, ultrasonic inspection using phased array technique (PAUT) is applied. Because thick-walled copper is not commonly used as a structural material, previous experience on Phased Array Ultrasonic Testing for this type of application is limited. The paper presents the progress in understanding the amplitudes and attenuation changes acting on the Phased Array Ultrasonic Testing inspection of copper canisters. Previous studies showed the existence of a low pass filtering effect and a heterogeneous grain size distribution along the depth, thus affecting both the detectability of defects and their "Probability of Detection" determination. Consequently, the difference between the first and second back wall echoes were not sufficient to determine the local attenuation (within the inspection range), which affects the signal response for each individual defect. Experimental evaluation of structural attenuation was carried out onto step-wedge samples cut from full-size, extruded and pierced & drawn, copper canisters. Effective attenuation values has been implemented in numerical simulations to achieve a Multi Parameter Probability of Detection and to formulate a Model Assisted Probability of Detection through a Monte-Carlo extraction model.

  1. Adaptive disturbance attenuation via logic-based switching

    NARCIS (Netherlands)

    Battistelli, Giorgio; Mari, Daniele; Selvi, Daniela; Tesi, Alberto; Tesi, Pietro


    The problem of attenuating unknown and possibly time-varying disturbances acting on a linear time-invariant dynamical system is addressed by means of an adaptive switching control approach. Given a family of pre-designed stabilizing controllers, a supervisory unit infers in real-time the potential b

  2. Timing attention : Cuing target onset interval attenuates the attentional blink

    NARCIS (Netherlands)

    Martens, S; Johnson, A


    Three experiments tested whether the attentional blink (AB; a deficit in reporting the second of two targets when it occurs 200-500 msec after the first) can be attenuated by providing information about the target onset asynchrony (TOA) of the second target relative to the first. Blocking the TOA di

  3. Lg Attenuation Characteristic of Gujarat Region (Western India) (United States)

    Jaiswal, Namrata; Singh, Chandrani


    We estimate the Lg attenuation characteristics of the Gujarat Region in Western India by using a reliable two-station method. This region comes under the V, IV and III seismicity zone. So, in India this is the seismic active region other than Himalayas, which shows high seismicity. Lg is typically the most prominent short-period seismic phase on high frequency seismogram observed over the continental paths from regional to teleseimic distance. We use data from 15 earthquakes with magnitude > 5 mb and focal depth Lg Q (Q0) values between many pairs of stations. Finally, 5 events with 70 high-quality inter-station paths were selected from 117 possible pairs of stations that are (1) aligned approximately with the source and (2) separated enough to permit the use of the standard two-station method for Lg Q measurement. Spatial variations in Q0 have been noticed across the Gujarat region. Low Q0 ( 300) value. These observations are consistent with the results of the body wave attenuation structure reported for the region. The variations in the attenuation characteristics may be caused due to both the intrinsic and scattering contributions caused by thermal effects, sedimentary layer thickness as well as heterogeneities present below the study region. Our results are found to be comparable with the previous studies of the attenuation characteristics of the Gujarat region.

  4. Attenuation of ground vibrations due to different technical sources

    Institute of Scientific and Technical Information of China (English)

    L. Auersch; S. Said


    The attenuation of technically induced surface waves is studied theoretically and experimentally. In this paper, nineteen measurements of ground vibrations induced by eight different technical sources including road and rail traffic, vibratory and impulsive construction work or pile driving, explosions, hammer impulses and mass drops are described, and it is shown that the technically induced ground vibrations exhibit a power-law attenuation v ~ r where the exponents q are in the range of 0.5 to 2.0 and depend on the source types. Comparisons performed demonstrate that the measured exponents are considerably higher than theoretically expected. Some potential effects on ground vibration attenuation are theoretically analyzed. The most important effect is due to the material or scattering damping. Each frequency component is attenuated exponentially as exp(-kr), but for a broad-band excitation, the sum of the exponential laws also yields a power law but with a high exponent. Additional effects are discussed, for example the dispersion of the Rayleigh wave due to soil layering, which yields an additional exponent of 0.5 in cases of impulsive loading.

  5. Pyrrolidine Dithiocarbamate Attenuates Paraquat-Induced Lung Injury in Rats

    Directory of Open Access Journals (Sweden)

    Xiuli Chang


    PQ+PDTC-treated groups than that of PQ-treated groups (P<.05. The histopathological changes in the PQ+PDTC-treated groups were milder than those of PQ groups. Our results suggested that PDTC treatment significantly attenuated paraquat-induced pulmonary damage.

  6. Body Wave Crustal Attenuation Characteristics in the Garhwal Himalaya, India (United States)

    Negi, Sanjay S.; Paul, Ajay; Joshi, Anand; Kamal


    We estimate frequency-dependent attenuation of P and S waves in Garhwal Himalaya using the extended coda normalization method for the central frequencies 1.5, 2, 3, 4, 6, 8, 10, 12, and 16 Hz, with earthquake hypocentral distance ranging from 27 to 200 km. Forty well-located local earthquake waveforms were used to study the seismic attenuation characteristics of the Garhwal Himalaya, India, as recorded by eight stations operated by Wadia Institute of Himalayan Geology, Dehradun, India, from 2007 to 2012. We find frequency-dependent P and S wave quality factors as defined by the relations Q P = 56 ± 8 f 0.91±0.002 and Q S = 151 ± 8 f 0.84±0.002 by fitting a power-law frequency dependence model for the estimated values over the whole region. Both the Q P and Q S values indicate strong attenuation in the crust of Garhwal Himalaya. The ratio of Q S/ Q P > 1 obtained for the entire analyzed frequency range suggests that the scattering loss is due to a random and high degree of heterogeneities in the earth medium, playing an important role in seismic wave attenuation in the Himalayan crust.

  7. The Ultraviolet Attenuation Law in Backlit Spiral Galaxies

    CERN Document Server

    Keel, William C; Holwerda, Benne W; Lintott, Chris J; Schawinski, Kevin


    (Abridged) The effective extinction law (attenuation behavior) in galaxies in the emitted ultraviolet is well known only for actively star-forming objects and combines effects of the grain properties, fine structure in the dust distribution, and relative distributions of stars and dust. We use GALEX, XMM Optical Monitor, and HST data to explore the UV attenuation in the outer parts of spiral disks which are backlit by other UV-bright galaxies, starting with candidates provided by Galaxy Zoo participants. Our analysis incorporates galaxy symmetry, using non-overlapping regions of each galaxy to derive error estimates on the attenuation measurements. The entire sample has an attenuation law close to the Calzetti et al. (1994) form; the UV slope for the overall sample is substantially shallower than found by Wild et al. (2011), a reasonable match to the more distant galaxies in our sample but not to the weighted combination including NGC 2207. The nearby, bright spiral NGC 2207 alone gives accuracy almost equal ...

  8. Laboratory measurements of seismic attenuation in partially saturated rocks (United States)

    Chapman, Samuel; Tisato, Nicola; Quintal, Beatriz; Holliger, Klaus


    Laboratory measurements of seismic attenuation and transient pore fluid pressure are performed on partially saturated Berea sandstone and synthetic borosilicate samples. Various degrees of water (liquid) and nitrogen (gas) saturation are considered. These measurements are carried out at room temperature and under confining pressures varying from ambient conditions up to 25 MPa. The cylindrical samples are 25 cm long and have a diameter of 7.6 cm. In the context of the experimental setup, the solid frames of both the Berea sandstone and the borosilicate samples can be considered homogenous, which in turn allows for isolating and exploring the effects of partial saturation on seismic attenuation. We employ the sub-resonance method, which is based on the application of a time-harmonic vertical stress to the top of the sample and the measurement of the thus resulting strain. For any given frequency, the attenuation is then inferred as the tangent of the phase shift between the applied stress and the observed strain. Using five equally spaced sensors along the central axis of the cylindrical sample, we measure the transient fluid pressure induced by the application of a step-function-type vertical stress to the top of the sample. Both the sensors and the sample are sealed off with the regard to the confining environment. Together with the numerical results from corresponding compressibility tests based on the quasi-static poroelastic equations, these transient fluid pressure measurements are then used to assist the interpretation of the seismic attenuation measurements.

  9. Bioavailability of jarosite for stimulating acid mine drainage attenuation (United States)

    Coggon, Matthew; Becerra, Caryl Ann; Nüsslein, Klaus; Miller, Karen; Yuretich, Richard; Ergas, Sarina J.


    Biological reduction of iron-sulfate minerals, such as jarosite, has the potential to contribute to the natural attenuation of acid mine drainage (AMD) sites. Previous studies of AMD attenuation at Davis Mine, an abandoned pyrite mine in Rowe Massachusetts, provided evidence of iron and sulfate reduction by indigenous bacteria. Jarosite is a large component of the sediment at Davis Mine and may play a role in AMD attenuation. In this study, microcosms were constructed with groundwater and sediment from Davis Mine and amended with glycerol, nitrogen and phosphorus (GNP) and naturally formed natrojarosite. Over time, higher total iron, sulfate, pH and sodium concentrations and lower oxidation-reduction potentials were observed in microcosms amended with GNP and jarosite, compared with unamended microcosms and killed controls. Geochemical modeling predicted jarosite precipitation under microcosm conditions, suggesting that abiotic processes were unlikely contributors to jarosite dissolution. SEM imaging at the jarosite surface showed microbial attachment. Microbial community composition analysis revealed a shift to higher populations of Clostridia, which are known to reduce both iron and sulfate. The results show that jarosite may be utilized as an electron acceptor by iron and/or sulfate reducing bacteria at Davis Mine and its presence may aid in the attenuation of AMD.

  10. Attenuated familial adenomatous polyposis (AFAP). A review of the literature

    DEFF Research Database (Denmark)

    Knudsen, Anne Lyster; Bisgaard, Marie Luise; Bülow, Steffen


    Over the last decade, a subset of familial adenomatous polyposis (FAP) patients with a milder course of disease termed attenuated familial adenomatous polyposis (AFAP) has been described. AFAP is not well-defined as a disease entity - the reports on AFAP are largely casuistic or only deal...

  11. Attenuated familial adenomatous polyposis (AFAP). A review of the literature

    DEFF Research Database (Denmark)

    Knudsen, Anne Lyster; Bisgaard, Marie Luise; Bülow, Steffen


    Over the last decade, a subset of familial adenomatous polyposis (FAP) patients with a milder course of disease termed attenuated familial adenomatous polyposis (AFAP) has been described. AFAP is not well-defined as a disease entity - the reports on AFAP are largely casuistic or only deal with a ...

  12. Seismic wave attenuation and velocity dispersion in UAE carbonates (United States)

    Ogunsami, Abdulwaheed Remi

    Interpreting the seismic property of fluids in hydrocarbon reservoirs at low frequency scale has been a cherished goal of petroleum geophysics research for decades. Lately, there has been tremendous interest in understanding attenuation as a result of fluid flow in porous media. Although interesting, the emerging experimental and theoretical information still remain ambiguous and are practically not utilized for reasons not too obscure. Attenuation is frequency dependent and hard to measure in the laboratory at low frequency. This thesis describes and reports the results of an experimental study of low frequency attenuation and velocity dispersion on a selected carbonate reservoir samples in the United Arab Emirates (UAE). For the low frequency measurements, stress-strain method was used to measure the moduli from which the velocity is derived. Attenuation was measured as the phase difference between the applied stress and the strain. For the ultrasonic component, the pulse propagation method was employed. To study the fluid effect especially at reservoir in situ conditions, the measurements were made dry and saturated with liquid butane and brine at differential pressures of up to 5000 psi with pore pressure held constant at 500 psi. Similarly to what has been documented in the literatures for sandstone, attenuation of the bulk compressibility mode dominates the losses in these dry and somewhat partially saturated carbonate samples with butane and brine. Overall, the observed attenuation cannot be simply said to be frequency dependent within this low seismic band. While attenuation seems to be practically constant in the low frequency band for sample 3H, such conclusion cannot be made for sample 7H. For the velocities, significant dispersion is observed and Gassmann generally fails to match the measured velocities. Only the squirt model fairly fits the velocities, but not at all pressures. Although the observed dispersion is larger than Biot's prediction, the fact

  13. Modeling transmission and scatter for photon beam attenuators. (United States)

    Ahnesjö, A; Weber, L; Nilsson, P


    The development of treatment planning methods in radiation therapy requires dose calculation methods that are both accurate and general enough to provide a dose per unit monitor setting for a broad variety of fields and beam modifiers. The purpose of this work was to develop models for calculation of scatter and transmission for photon beam attenuators such as compensating filters, wedges, and block trays. The attenuation of the beam is calculated using a spectrum of the beam, and a correction factor based on attenuation measurements. Small angle coherent scatter and electron binding effects on scattering cross sections are considered by use of a correction factor. Quality changes in beam penetrability and energy fluence to dose conversion are modeled by use of the calculated primary beam spectrum after passage through the attenuator. The beam spectra are derived by the depth dose effective method, i.e., by minimizing the difference between measured and calculated depth dose distributions, where the calculated distributions are derived by superposing data from a database for monoenergetic photons. The attenuator scatter is integrated over the area viewed from the calculation point of view using first scatter theory. Calculations are simplified by replacing the energy and angular-dependent cross-section formulas with the forward scatter constant r2(0) and a set of parametrized correction functions. The set of corrections include functions for the Compton energy loss, scatter attenuation, and secondary bremsstrahlung production. The effect of charged particle contamination is bypassed by avoiding use of dmax for absolute dose calibrations. The results of the model are compared with scatter measurements in air for copper and lead filters and with dose to a water phantom for lead filters for 4 and 18 MV. For attenuated beams, downstream of the buildup region, the calculated results agree with measurements on the 1.5% level. The accuracy was slightly less in situations

  14. Signal attenuation as a rat model of obsessive compulsive disorder. (United States)

    Goltseker, Koral; Yankelevitch-Yahav, Roni; Albelda, Noa S; Joel, Daphna


    In the signal attenuation rat model of obsessive-compulsive disorder (OCD), lever-pressing for food is followed by the presentation of a compound stimulus which serves as a feedback cue. This feedback is later attenuated by repeated presentations of the stimulus without food (without the rat emitting the lever-press response). In the next stage, lever-pressing is assessed under extinction conditions (i.e., no food is delivered). At this stage rats display two types of lever-presses, those that are followed by an attempt to collect a reward, and those that are not. The latter are the measure of compulsive-like behavior in the model. A control procedure in which rats do not experience the attenuation of the feedback cue serves to distinguish between the effects of signal attenuation and of extinction. The signal attenuation model is a highly validated model of OCD and differentiates between compulsive-like behaviors and behaviors that are repetitive but not compulsive. In addition the measures collected during the procedure eliminate alternative explanations for differences between the groups being tested, and are quantitative, unbiased and unaffected by inter-experimenter variability. The major disadvantages of this model are the costly equipment, the fact that it requires some technical know-how and the fact that it is time-consuming compared to other models of OCD (11 days). The model may be used for detecting the anti- or pro-compulsive effects of pharmacological and non-pharmacological manipulations and for studying the neural substrate of compulsive behavior.

  15. Modelling the attenuation in the ATHENA finite elements code for the ultrasonic testing of austenitic stainless steel welds. (United States)

    Chassignole, B; Duwig, V; Ploix, M-A; Guy, P; El Guerjouma, R


    Multipass welds made in austenitic stainless steel, in the primary circuit of nuclear power plants with pressurized water reactors, are characterized by an anisotropic and heterogeneous structure that disturbs the ultrasonic propagation and makes ultrasonic non-destructive testing difficult. The ATHENA 2D finite element simulation code was developed to help understand the various physical phenomena at play. In this paper, we shall describe the attenuation model implemented in this code to give an account of wave scattering phenomenon through polycrystalline materials. This model is in particular based on the optimization of two tensors that characterize this material on the basis of experimental values of ultrasonic velocities attenuation coefficients. Three experimental configurations, two of which are representative of the industrial welds assessment case, are studied in view of validating the model through comparison with the simulation results. We shall thus provide a quantitative proof that taking into account the attenuation in the ATHENA code dramatically improves the results in terms of the amplitude of the echoes. The association of the code and detailed characterization of a weld's structure constitutes a remarkable breakthrough in the interpretation of the ultrasonic testing on this type of component.

  16. Physics Laboratory in UEC (United States)

    Takada, Tohru; Nakamura, Jin; Suzuki, Masaru

    All the first-year students in the University of Electro-Communications (UEC) take "Basic Physics I", "Basic Physics II" and "Physics Laboratory" as required subjects; Basic Physics I and Basic Physics II are calculus-based physics of mechanics, wave and oscillation, thermal physics and electromagnetics. Physics Laboratory is designed mainly aiming at learning the skill of basic experimental technique and technical writing. Although 95% students have taken physics in the senior high school, they poorly understand it by connecting with experience, and it is difficult to learn Physics Laboratory in the university. For this reason, we introduced two ICT (Information and Communication Technology) systems of Physics Laboratory to support students'learning and staff's teaching. By using quantitative data obtained from the ICT systems, we can easily check understanding of physics contents in students, and can improve physics education.

  17. CT-based attenuation and scatter correction compared with uniform attenuation correction in brain perfusion SPECT imaging for dementia (United States)

    Gillen, Rebecca; Firbank, Michael J.; Lloyd, Jim; O'Brien, John T.


    This study investigated if the appearance and diagnostic accuracy of HMPAO brain perfusion SPECT images could be improved by using CT-based attenuation and scatter correction compared with the uniform attenuation correction method. A cohort of subjects who were clinically categorized as Alzheimer’s Disease (n=38 ), Dementia with Lewy Bodies (n=29 ) or healthy normal controls (n=30 ), underwent SPECT imaging with Tc-99m HMPAO and a separate CT scan. The SPECT images were processed using: (a) correction map derived from the subject’s CT scan or (b) the Chang uniform approximation for correction or (c) no attenuation correction. Images were visually inspected. The ratios between key regions of interest known to be affected or spared in each condition were calculated for each correction method, and the differences between these ratios were evaluated. The images produced using the different corrections were noted to be visually different. However, ROI analysis found similar statistically significant differences between control and dementia groups and between AD and DLB groups regardless of the correction map used. We did not identify an improvement in diagnostic accuracy in images which were corrected using CT-based attenuation and scatter correction, compared with those corrected using a uniform correction map.


    Laboratory experiments show that amorphous and poorly crystallized ferric iron hydroxides have much greater capacity to attenuate arsenic compared to clays and other aluminosilicate minerals. Studies (e.g., Lin and Qvarfort, 1996) showed that a sudden change in geochemical condit...

  19. Physics News in 1983. (United States)

    Schewe, Phillip F., Ed.

    Information is provided on some of the interesting and newsworthy developments in physics and its related fields during 1983. Areas considered include: (1) acoustics; (2) astrophysics; (3) condensed matter physics; (4) crystallography; (5) physics education; (6) electron and atomic physics; (7) elementary particle physics; (8) fluid dynamics; (9)…

  20. Some Physics Not in the Physical Review. (United States)

    Varney, Robert N.


    Discusses how physics was done at the University of California at Berkeley in the 1930s, focusing on the faculty and their accomplishments, physics experiments, physics instruments/equipment (cyclotron and rhumbatron), and research problems and their solutions. Includes reminiscences about lectures on thermodynamics presented by Otto Stern during…

  1. Nuclear physics in particle therapy: a review (United States)

    Durante, Marco; Paganetti, Harald


    Charged particle therapy has been largely driven and influenced by nuclear physics. The increase in energy deposition density along the ion path in the body allows reducing the dose to normal tissues during radiotherapy compared to photons. Clinical results of particle therapy support the physical rationale for this treatment, but the method remains controversial because of the high cost and of the lack of comparative clinical trials proving the benefit compared to x-rays. Research in applied nuclear physics, including nuclear interactions, dosimetry, image guidance, range verification, novel accelerators and beam delivery technologies, can significantly improve the clinical outcome in particle therapy. Measurements of fragmentation cross-sections, including those for the production of positron-emitting fragments, and attenuation curves are needed for tuning Monte Carlo codes, whose use in clinical environments is rapidly increasing thanks to fast calculation methods. Existing cross sections and codes are indeed not very accurate in the energy and target regions of interest for particle therapy. These measurements are especially urgent for new ions to be used in therapy, such as helium. Furthermore, nuclear physics hardware developments are frequently finding applications in ion therapy due to similar requirements concerning sensors and real-time data processing. In this review we will briefly describe the physics bases, and concentrate on the open issues.

  2. Nuclear physics in particle therapy: a review. (United States)

    Durante, Marco; Paganetti, Harald


    Charged particle therapy has been largely driven and influenced by nuclear physics. The increase in energy deposition density along the ion path in the body allows reducing the dose to normal tissues during radiotherapy compared to photons. Clinical results of particle therapy support the physical rationale for this treatment, but the method remains controversial because of the high cost and of the lack of comparative clinical trials proving the benefit compared to x-rays. Research in applied nuclear physics, including nuclear interactions, dosimetry, image guidance, range verification, novel accelerators and beam delivery technologies, can significantly improve the clinical outcome in particle therapy. Measurements of fragmentation cross-sections, including those for the production of positron-emitting fragments, and attenuation curves are needed for tuning Monte Carlo codes, whose use in clinical environments is rapidly increasing thanks to fast calculation methods. Existing cross sections and codes are indeed not very accurate in the energy and target regions of interest for particle therapy. These measurements are especially urgent for new ions to be used in therapy, such as helium. Furthermore, nuclear physics hardware developments are frequently finding applications in ion therapy due to similar requirements concerning sensors and real-time data processing. In this review we will briefly describe the physics bases, and concentrate on the open issues.

  3. Monitored Natural Attenuation For Inorganic Contaminants In Ground Water - Technical Issues (United States)

    Remediation of ground water contaminated with radionuclides may be achieved using attenuation-based technologies. These technologies may rely on engineered processes (e.g., bioremediation) or natural processes (e.g., monitored natural attenuation) within the subsurface. In gene...

  4. Estimation of seismic attenuation of gas hydrate bearing sediments from multi-channel seismic data: A case study from Krishna-Godavari offshore basin

    Digital Repository Service at National Institute of Oceanography (India)

    Dewangan, P.; Mandal, R.; Jaiswal, P.; Ramprasad, T.; Sriram, G.

    and distribution of gas hydrate within the host sediments. Several rock physics models like the cementation theory (Ecker et al., 1998), effective medium model (EMM; Helgerud et al., 1999), self-consistent approximation (SCA) and differential effective medium... to demonstrate the applicability of the method towards the estimation of seismic attenuation from multi-channel seismic data. 2. Theory A seismic wave travelling through the medium experiences absorption, spreading loss and dispersion due to which the wave...

  5. New Physics Search in Flavour Physics

    Energy Technology Data Exchange (ETDEWEB)

    Hurth, Tobias; /CERN /SLAC


    With the running B, kaon and neutrino physics experiments, flavour physics takes centre stage within today's particle physics. We discuss the opportunities offered by these experiments in our search for new physics beyond the SM and discuss their complementarity to collider physics. We focus on rare B and kaon decays, highlighting specific observables in an exemplary mode. We also comment on the so-called B {yields} {pi}{pi} and B {yields} K{pi} puzzles. Moreover, we briefly discuss the restrictive role of long-distance strong interactions and some new tools such as QCD factorization and SCET to handle them.

  6. Bacteria attenuation by iron electrocoagulation governed by interactions between bacterial phosphate groups and Fe(III) precipitates. (United States)

    Delaire, Caroline; van Genuchten, Case M; Amrose, Susan E; Gadgil, Ashok J


    Iron electrocoagulation (Fe-EC) is a low-cost process in which Fe(II) generated from an Fe(0) anode reacts with dissolved O2 to form (1) Fe(III) precipitates with an affinity for bacterial cell walls and (2) bactericidal reactive oxidants. Previous work suggests that Fe-EC is a promising treatment option for groundwater containing arsenic and bacterial contamination. However, the mechanisms of bacteria attenuation and the impact of major groundwater ions are not well understood. In this work, using the model indicator Escherichia coli (E. coli), we show that physical removal via enmeshment in EC precipitate flocs is the primary process of bacteria attenuation in the presence of HCO3(-), which significantly inhibits inactivation, possibly due to a reduction in the lifetime of reactive oxidants. We demonstrate that the adhesion of EC precipitates to cell walls, which results in bacteria encapsulation in flocs, is driven primarily by interactions between EC precipitates and phosphate functional groups on bacteria surfaces. In single solute electrolytes, both P (0.4 mM) and Ca/Mg (1-13 mM) inhibited the adhesion of EC precipitates to bacterial cell walls, whereas Si (0.4 mM) and ionic strength (2-200 mM) did not impact E. coli attenuation. Interestingly, P (0.4 mM) did not affect E. coli attenuation in electrolytes containing Ca/Mg, consistent with bivalent cation bridging between bacterial phosphate groups and inorganic P sorbed to EC precipitates. Finally, we found that EC precipitate adhesion is largely independent of cell wall composition, consistent with comparable densities of phosphate functional groups on Gram-positive and Gram-negative cells. Our results are critical to predict the performance of Fe-EC to eliminate bacterial contaminants from waters with diverse chemical compositions.

  7. Attenuation of arsenic in a karst subterranean stream and correlation with geochemical factors: a case study at Lihu, South China. (United States)

    Zhang, Liankai; Yang, Hui; Tang, Jiansheng; Qin, Xiaoqun; Yu, Au Yik


    Arsenic (As) pollutants generated by human activities in karst areas flow into subterranean streams and contaminate groundwater easily because of the unique hydrogeological characteristics of karst areas. To elucidate the reaction mechanisms of arsenic in karst subterranean streams, physical-chemical analysis was conducted by an inductively coupled plasma mass spectrometer and an X-ray fluorescence spectrometer. The results show that inorganic species account for most of the total arsenic, whereas organic arsenic is not detected or occurs in infinitesimal amounts. As(III) accounts for 51.0%±9.9% of the total inorganic arsenic. Arsenic attenuation occurs and the attenuation rates of total As, As(III) and As(V) in the Lihu subterranean stream are 51%, 36% and 59%, respectively. To fully explain the main geochemical factors influencing arsenic attenuation, SPSS 13.0 and CANOCO 4.5 bundled with CanoDraw for Windows were used for simple statistical analysis and redundancy analysis (RDA). Eight main factors, i.e., sediment iron (SFe), sediment aluminum (SAl), sediment calcium (SCa), sediment organic matter (SOM), sediment manganese (SMn), water calcium (WCa(2+)), water magnesium (WMg(2+)), and water bicarbonate ion (WHCO3(-)) were extracted from thirteen indicators. Their impacts on arsenic content rank as: SFe>SCa>WCa(2+)>SAl>WHCO3(-)>SMn>SOM>WMg(2+). Of these factors, SFe, SAl, SCa, SOM, SMn, WMg(2+) and WCa(2+) promote arsenic attenuation, whereas WHCO3(-) inhibits it. Further investigation revealed that the redox potential (Eh) and pH are adverse to arsenic removal. The dramatic distinction between karst and non-karst terrain is that calcium and bicarbonate are the primary factors influencing arsenic migration in karst areas due to the high calcium concentration and alkalinity of karst water.

  8. Physical Activity Assessment (United States)

    Current evidence convincingly indicates that physical activity reduces the risk of colon and breast cancer. Physical activity may also reduce risk of prostate cancer. Scientists are also evaluating potential relationships between physical activity and other cancers.

  9. Quantum Physics for Beginners. (United States)

    Strand, J.


    Suggests a new approach for teaching secondary school quantum physics. Reviews traditional approaches and presents some characteristics of the three-part "Quantum Physics for Beginners" project, including: quantum physics, quantum mechanics, and a short historical survey. (SK)

  10. Physical properties and fisheries

    Digital Repository Service at National Institute of Oceanography (India)

    Antony, M.K.

    The physical aspects influencing the different stages of behaviour of the marine fish can be divided into two categories (1) the physical properties of the ocean like temperature, salinity, oxygen, high penetration etc.; and (2) the physical...

  11. Facts about Physical Activity (United States)

    ... Nutrition Physical Activity Overweight & Obesity Healthy Weight Breastfeeding Micronutrient Malnutrition State and Local Programs Facts about Physical ... Nutrition Physical Activity Overweight & Obesity Healthy Weight Breastfeeding Micronutrient Malnutrition State and Local Programs File Formats Help: ...

  12. BAM! Physical Activity (United States)

    ... Smarts Links Fuel Up for Fun Power Packing Physical Activity Xpert Opinion Activity Calendar Activity Cards Ballet Baseball ... Disaster - Are You at Risk? Disaster - Helping Hands Physical Activity - Questions Physical Activity - Active or Not, Here it ...

  13. Estimation of compressional seismic wave attenuation of carbonate rocks in Abu Dhabi, United Arab Emirates (United States)

    Bouchaala, Fateh; Ali, Mohammed Y.; Farid, Asam


    The subsurface geology of Abu Dhabi in the United Arab Emirates is primarily composed of carbonate rocks. Such media are known to be highly heterogeneous. Very few studies have attempted to estimate attenuation in carbonate rocks. In Abu Dhabi no attenuation profile has been published. This study provides the first seismic wave attenuation profiles in Abu Dhabi using dense array of VSP data. We estimated three attenuation profiles: the apparent, the scattering, and the intrinsic attenuations. The apparent attenuation profile was computed using amplitude decay and spectral-ratio methods. The scattering attenuation profile was estimated using a generalized reflection-transmission matrix forward model. It is usually estimated from the sonic log, but to be more consistent with the apparent attenuation, we succeeded in this paper to estimate it from the VSP data. We subtracted the scattering attenuation from the apparent attenuation to deduce the intrinsic attenuation. The results of the study indicate that the scattering attenuation is significant compared to the published studies that are mainly based on clastic rocks. The high scattering attenuation can reach up to 0.02. It can be explained by the strong heterogeneity of the carbonate rocks. This study demonstrates that the Simsima and Rus Formations have considerable scattering and intrinsic attenuations. These formations are considered aquifers in Abu Dhabi; we therefore interpreted this high intrinsic attenuation zones to be due to the heterogeneity and to the fluids contained in these formations. The Umm-Er-Radhuma Formation is a more homogenous formation with limited aquifer potential. Hence, scattering and intrinsic attenuations of the Umm-Er-Radhuma Formation are low.

  14. Project X: Physics Opportunities

    CERN Document Server

    Kronfeld, Andreas S; Al-Binni, Usama; Altmannshofer, Wolfgang; Ankenbrandt, Charles; Babu, Kaladi; Banerjee, Sunanda; Bass, Matthew; Batell, Brian; Baxter, David V; Berezhiani, Zurab; Bergevin, Marc; Bernstein, Robert; Bhattacharya, Sudeb; Bishai, Mary; Blum, Thomas; Bogacz, S Alex; Brice, Stephen J; Brod, Joachim; Bross, Alan; Buchoff, Michael; Burgess, Thomas W; Carena, Marcela; Castellanos, Luis A; Chattopadhyay, Subhasis; Chen, Mu-Chun; Cherdack, Daniel; Christ, Norman H; Chupp, Tim; Cirigliano, Vincenzo; Coloma, Pilar; Coppola, Christopher E; Cowsik, Ramanath; Crabtree, J Allen; Delahaye, Jean-Pierre; Denisov, Dmitri; deNiverville, Patrick; de Gouvêa, André; Dharmapalan, Ranjan; Dolgov, Alexander; Dvali, Georgi; Eichten, Estia; Engelfried, Jürgen; Ferguson, Phillip D; Gabriel, Tony; Gal, Avraham; Gallmeier, Franz; Ganezer, Kenneth S; Gardner, Susan; Glenzinski, Douglas; Godfrey, Stephen; Golubeva, Elena S; Gori, Stefania; Graves, Van B; Greene, Geoffrey; Griffard, Cory L; Haisch, Ulrich; Handler, Thomas; Hartfiel, Brandon; Hawari, Ayman; Heilbronn, Lawrence; Hill, James E; Huber, Patrick; Jaffe, David E; Johnson, Christian; Kamyshkov, Yuri; Kaplan, Daniel M; Kerbikov, Boris; Kiburg, Brendan; Kirk, Harold G; Klein, Andreas; Knoepfel, Kyle; Kopeliovich, Boris; Kopeliovich, Vladimir; Kopp, Joachim; Korsch, Wolfgang; Kribs, Graham; Lipton, Ronald; Liu, Chen-Yu; Lorenzon, Wolfgang; Lu, Zheng-Tian; Makins, Naomi C R; McKeen, David; Mills, Geoffrey; Mohapatra, Rabindra; Mokhov, Nikolai V; Mocko, Michael; Muhrer, Guenter; Mumm, Pieter; Okun, Lev; Neuffer, David; Palmer, Mark A; Palmer, Robert; Pattie, Robert W; Phillips, David G; Pronsikh, Vitaly; Pitts, Kevin; Pospelov, Maxim; Quigg, Chris; Ramberg, Erik; Ray, Amlan; Reimer, Paul E; Richards, David G; Ritz, Adam; Roy, Amit; Ruggles, Arthur; Ryne, Robert; Sarkar, Utpal; Saunders, Andy; Semertzidis, Yannis K; Serebrov, Anatoly; Shimizu, Hirohiko; Shrock, Robert; Snopok, Pavel V; Snow, William M; Sikdar, Arindam K; Soha, Aria; Spanier, Stefan; Striganov, Sergei; Tang, Zhaowen; Townsend, Lawrence; Urheim, Jon; Vainshtein, Arkady; Van Kooten, Richard J; Van de Water, Richard; Van de Water, Ruth S; Wehring, Bernard; Whitehead, Lisa; Wilson, Robert J; Worcester, Elizabeth; Young, Albert R; Wester, William C; Zeller, Geralyn


    Part 2 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". In this Part, we outline the particle-physics program that can be achieved with Project X, a staged superconducting linac for intensity-frontier particle physics. Topics include neutrino physics, kaon physics, muon physics, electric dipole moments, neutron-antineutron oscillations, new light particles, hadron structure, hadron spectroscopy, and lattice-QCD calculations.

  15. Physiological and Antigenic Characteristics of Virulent and Attenuated Strains of Legionella pneumophila (Philadelphia 3) (United States)


    CHARACTERISTICS OF I, VIRULENT AND ATTENUATED5TRAINS OF LEGIONELLA Interim PNEUMOPHILA (PHILADELPHIA 3) 6 . PERFORMING ORG. REPORT NUMBER 70 AUTHOR(*) B...number) Several methods were used to cJvrtcterize selected virulent and attenuated strains of Legionella pneumophila serogroup 1. The cultural...Antigenic Characteristics of Virulent and Attenuated Strains of Legionella pneumophila (Philadelphia 3) JOSEPH D. RISTROPH, KENNETH W. HEDLUND, AND

  16. Effects of Hearing Protection Device Attenuation on Unmanned Aerial Vehicle (UAV) Audio Signatures (United States)


    ARL-TR-7639 ● MAR 2016 US Army Research Laboratory Effects of Hearing Protection Device Attenuation on Unmanned Aerial Vehicle ...Research Laboratory Effects of Hearing Protection Device Attenuation on Unmanned Aerial Vehicle (UAV) Audio Signatures by Melissa Bezandry...further study. In the future, the work could aid in the development of a filter to attenuate unmanned aerial vehicle noise in different environmental

  17. Earth-To-Space Improved Model for Rain Attenuation Prediction at Ku-Band

    Directory of Open Access Journals (Sweden)

    Mandeep S.J. Singh


    Full Text Available A model for predicting rain attenuation on earth-to-space was developed by using the measurement data obtained from tropical and equatorial region. The proposed rain attenuation model uses the complete rainfall rate cumulative distribution as input data. It was shown that significant improvements in terms of prediction error over existing attenuation model obtained.

  18. Attenuation correction for X-ray emission computed tomography of laser-produced plasma

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yen-Wei; Nakao, Zensho [Ryukyus Univ., Nishihara, Okinawa (Japan). Faculty of Engineering; Tamura, Shinichi


    An attenuation correction method was proposed for laser-produced plasma emission computed tomography (ECT), which is based on a relation of the attenuation coefficient and the emission coefficient in plasma. Simulation results show that the reconstructed images are dramatically improved in comparison to the reconstructions without attenuation correction. (J.P.N.)

  19. Velocity and attenuation of sound in arterial tissues (United States)

    Rooney, J. A.; Gammell, P. M.; Hestenes, J. D.; Chin, H. P.; Blankenhorn, D. H.


    The velocity of sound in excised human and canine arterial tissues is measured in order to serve as a basis for the development and application of ultrasonic techniques for the diagnosis of atherosclerotic lesions. Measurements of sound velocity at different regions of 11 human and six canine aortas were made by a time delay spectrometer technique at frequencies from 2 to 10 MHz, and compared with ultrasonic attenuation parameters and the results of biochemical assays. Sound velocity is found to increase with increasing attenuation at all frequencies, and with increasing collagen content. A strong dependence of sound velocity on cholesterol content or low calcium contents is not observed, although velocities of up to 2000 m/sec are observed in highly organized calcified lesions. A decrease in velocity with decreasing temperature is also noted. It is thus concluded that it is principally the differences in tissue collagen levels that contribute to image formation according to sound velocity.

  20. Wave attenuation model for dephasing and measurement of conditional times

    Indian Academy of Sciences (India)

    A M Jayannavar; Colin Benjamin


    Inelastic scattering induces dephasing in mesoscopic systems. An analysis of previous models to simulate inelastic scattering in such systems is presented and a relatively new model based on wave attenuation is introduced. The problem of Aharonov–Bohm (AB) oscillations in conductance of a mesoscopic ring is studied. We show that the conductance is symmetric under flux reversal and the visibility of AB oscillations decays to zero as a function of the incoherence parameter, signaling dephasing. Further the wave attenuation model is applied to a fundamental problem in quantum mechanics, that of the conditional (reflection/transmission) times spent in a given region of space by a quantum particle before scattering off from that region.

  1. Numerical support of laboratory experiments: Attenuation and velocity estimations (United States)

    Saenger, Erik; Madonna, Claudio; Frehner, Marcel; Almqvist, Bjarne


    We show that numerical support of laboratory experiments can significantly increase the understanding and simplify the interpretation of the obtained laboratory results. First we perform simulations of the Seismic Wave Attenuation Module to measure seismic attenuation of reservoir rocks. Our findings confirm the accuracy of this system. However, precision can be further improved by optimizing the sensor positions. Second, we model wave propagation for an ultrasonic pulse transmission experiment used to determine pressure- and temperature-dependent seismic velocities in the rock. Multiple waves are identified in our computer experiment, including bar waves. The metal jacket that houses the sample assembly needs to be taken into account for a proper estimation of the ultrasonic velocities. This influence is frequency-dependent.

  2. Electroacupuncture attenuates neuropathic pain after brachial plexus injury

    Institute of Scientific and Technical Information of China (English)

    Shenyu Zhang; Hailiang Tang; Junming Zhou; Yudong Gu


    Electroacupuncture has traditionally been used to treat pain, but its effect on pain following brachial plexus injury is still unknown. In this study, rat models of an avulsion injury to the left brachial plexus root (associated with upper-limb chronic neuropathic pain) were given electroacu-puncture stimulation at bilateralQuchi(LI11),Hegu(LI04),Zusanli(ST36) andYanglingquan (GB34). After electroacupuncture therapy, chronic neuropathic pain in the rats’ upper limbs was signiifcantly attenuated. Immunolfuorescence staining showed that the expression of β-endorphins in the arcuate nucleus was signiifcantly increased after therapy. Thus, experimental ifndings indi-cate that electroacupuncture can attenuate neuropathic pain after brachial plexus injury through upregulatingβ-endorphin expression.

  3. Random seismic noise attenuation using the Wavelet Transform (United States)

    Aliouane, L.; Ouadfeul, S.; Boudella, A.; Eladj, S.


    In this paper we propose a technique of random noises attenuation from seismic data using the discrete and continuous wavelet transforms. Firstly the discrete wavelet transform (DWT) is applied to denoise seismic data. This last is based on the threshold method applied at the modulus of the DWT. After we calculate the continuous wavelet transform of the denoised seismic seismogram, the final denoised seismic seismogram is the continuous wavelet transform coefficients at the low scale. Application at a synthetic seismic seismogram shows the robustness of the proposed tool for random noises attenuation. We have applied this idea at a real seismic data of a vertical seismic profile realized in Algeria. Keywords: Seismic data, denoising, DWT, CWT, random noise.

  4. A novel live-attenuated vaccine candidate for mayaro Fever.

    Directory of Open Access Journals (Sweden)

    William J Weise


    Full Text Available Mayaro virus (MAYV is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a live-attenuated MAYV vaccine candidate. Testing in infant, immunocompetent as well as interferon receptor-deficient mice demonstrated a high degree of attenuation, strong induction of neutralizing antibodies, and efficacy against lethal challenge. This vaccine strain was also unable to infect mosquito cells, a major safety feature for a live vaccine derived from a mosquito-borne virus. Further preclinical development of this vaccine candidate is warranted to protect against this important emerging disease.

  5. Attenuation of rare earth elements in a boreal estuary (United States)

    Åström, Mats E.; Österholm, Peter; Gustafsson, Jon Petter; Nystrand, Miriam; Peltola, Pasi; Nordmyr, Linda; Boman, Anton


    This study focuses on attenuation of rare earth elements (REE) when a boreal creek, acidified and loaded with REE and other metals as a result of wetland drainage, empties into a brackish-water estuary (salinity MINTEQ version 3.0 and the Stockholm Humic Model after revision and updating, predicted that the dissolved (<0.45 μm) REE pool in the estuary is bound almost entirely to humic substances. Acid sulphate soils, the source of the REE and other metals in the creek water, are widespread on coastal plains worldwide and therefore the REE attenuation patterns and mechanisms identified in the studied estuary are relevant for recognition of similar geochemical processes and conditions in a variety of coastal locations.

  6. Depolarization and attenuation effects of radomes at 20 GHz (United States)

    Hendrix, Charles E.; McNally, James E.; Monzingo, Robert A.


    The problem of describing the attenuation and depolarization effects of a wet radome on a transmitted signal is considered by experiments carried out with two commonly used radome materials, ESSCOLAM-6 and ESSCOLAM-8. The results suggest that a two-component model of depolarization is required to account for the observed results. Predictions for the behavior of a complete radome are obtained, but full-scale testing with an operating radome to compare predicted and actual results remains to be done. An important conclusion is that, while highly water-repellent radome materials are desirable from the point of view of attenuation, they are not so desirable in terms of the degree of depolarization introduced between orthogonally polarized signal components in frequency-reuse systems.

  7. Experimental and theoretical studies on visible light attenuation in water

    CERN Document Server

    Simpson, A; Cho, H J; Liu, H


    In this study we describe lab experiments on determining the above water reflectance Rrs coefficient, and the water attenuation coefficient Kd for fresh water. Different types of screens (totally absorbent, gray, etc.) were submerged in water (0-0.6 m) and illuminated from outside. The spectral density of the water leaving radiance was measured for different depths. The results were ran by a code which took into account the geometry of the incident irradiation, the geometry of the screen under water, and boundary conditions at the water surface provided by the radiation transfer theory. From the experimental data and our model we obtain the spectral distribution of the attenuation coefficient for fresh water and compared it with other data in literature. These experiments, performed in the Nonlinear Wave Lab at ERAU# represent just a preliminary calibration of the experimental protocol. More tests with water of different degrees of turbidity, and possibly wave filed at the water surface are in progress and wi...

  8. Propagation and Attenuation Characteristics of Diesel Particulate Filter

    Institute of Scientific and Technical Information of China (English)

    GAO Wenzhi; SONG Chonglin; LIU Jianguo; GUAN Shunji


    Diesel particulate filter (DPF) is an important factor which influences the sound from exhaust system of an engine. In order to understand the propagation law of sound wave and predict the insertion loss in DPF, based on the general aero-dynamic equations and Darcy′s law, an acoustic property calculation model of DPF is constructed. Propagation and attenuation characteristics of the forward and backward propagating acoustic waves in the close and open pipe of the filter are investigated. The theoretical model is combined with experiment to investigate sound attenuation property of DPF. The insertion loss obtained from the experiment is compared with that computed for a DPF. The results from the experiment and theoretical calculation agree well.

  9. A novel live-attenuated vaccine candidate for mayaro Fever. (United States)

    Weise, William J; Hermance, Meghan E; Forrester, Naomi; Adams, A Paige; Langsjoen, Rose; Gorchakov, Rodion; Wang, Eryu; Alcorn, Maria D H; Tsetsarkin, Konstantin; Weaver, Scott C


    Mayaro virus (MAYV) is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a live-attenuated MAYV vaccine candidate. Testing in infant, immunocompetent as well as interferon receptor-deficient mice demonstrated a high degree of attenuation, strong induction of neutralizing antibodies, and efficacy against lethal challenge. This vaccine strain was also unable to infect mosquito cells, a major safety feature for a live vaccine derived from a mosquito-borne virus. Further preclinical development of this vaccine candidate is warranted to protect against this important emerging disease.

  10. Attenuation measurements of vacuum ultraviolet light in liquid argon revisited

    Energy Technology Data Exchange (ETDEWEB)

    Neumeier, A. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Dandl, T.; Himpsl, A. [Physik-Department E12, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Hofmann, M. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); KETEK GmbH, Hofer Straße 3, 81737 München (Germany); Oberauer, L.; Potzel, W.; Schönert, S. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Ulrich, A., E-mail: [Physik-Department E12, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany)


    The attenuation of vacuum ultraviolet light in liquid argon in the context of its application in large liquid noble gas detectors has been studied. Compared to a previous publication several technical issues concerning transmission measurements in general are addressed and several systematic effects were quantitatively measured. Wavelength-resolved transmission measurements have been performed from the vacuum ultraviolet to the near-infrared region. On the current level of sensitivity with a length of the optical path of 11.6 cm, no xenon-related absorption effects could be observed, and pure liquid argon is fully transparent down to the short wavelength cut-off of the experimental setup at 118 nm. A lower limit for the attenuation length of pure liquid argon for its own scintillation light has been estimated to be 1.10 m based on a very conservative approach.

  11. Attenuation of vacuum ultraviolet light in liquid argon

    CERN Document Server

    Neumeier, A; Oberauer, L; Potzel, W; Schönert, S; Dandl, T; Heindl, T; Ulrich, A; Wieser, J


    The transmission of liquid argon has been measured, wavelength resolved, for a wavelength interval from 118 to 250 nm. The wavelength dependent attenuation length is presented for pure argon. It is shown that no universal wavelength independent attenuation length can be assigned to liquid argon for its own fluorescence light due to the interplay between the wavelength dependent emission and absorption. A decreasing transmission is observed below 130 nm in both chemically cleaned and distilled liquid argon and assigned to absorption by the analogue of the first argon excimer continuum. For not perfectly cleaned argon a strong influence of impurities on the transmission is observed. Two strong absorption bands at 126.5 and 141.0 nm with approximately 2 and 4 nm width, respectively, are assigned to traces of xenon in argon. A broad absorption region below 180 nm is found for unpurified argon and tentatively attributed to the presence of water in the argon sample.

  12. Dust Attenuation in Hydrodynamic Simulations of Spiral Galaxies

    CERN Document Server

    Rocha, M; Primack, J R; Cox, T J; Rocha, Miguel; Jonsson, Patrik; Primack, Joel R.


    We study the effects of dust in hydrodynamic simulations of spiral galaxies when different radial metallicity gradients are assumed. SUNRISE, a Monte-Carlo radiative-transfer code, is used to make detailed calculations of the internal extinction of disk galaxies caused by their dust content. SUNRISE is used on eight different Smooth Particle Hydrodynamics (SPH) simulations of isolated spiral galaxies. These galaxies vary mainly in mass and hence luminosity, spanning a range in luminosities from -16 to -22 magnitudes in the B band. We focus on the attenuation in different wavelength bands as a function of the disk inclination and the luminosity of the models, and compare this to observations. Observations suggest different metallicity gradients for galaxies of different luminosities. These metallicity gradients were explored in our different models, finding that the resulting dust attenuation matches observations for edge-on galaxies, but do not show a linear behaviour in log axis ratio as some observations ha...

  13. Attenuation measurements of vacuum ultraviolet light in liquid argon revisited

    CERN Document Server

    Neumeier, A; Himpsl, A; Hofmann, M; Oberauer, L; Potzel, W; Schönert, S; Ulrich, A


    The attenuation of vacuum ultraviolet light in liquid argon in the context of its application in large liquid noble gas detectors has been studied. Compared to a previous publication several technical issues concerning transmission measurements in general are addressed and several systematic effects were quantitatively measured. Wavelength-resolved transmission measurements have been performed from the vacuum ultraviolet to the near-infrared region. On the current level of sensitivity with a length of the optical path of 11.6 cm, no xenon-related absorption effects could be observed, and pure liquid argon is fully transparent down to the short wavelength cut-off of the experimental setup at 118 nm. A lower limit for the attenuation length of pure liquid argon for its own scintillation light has been estimated to be 1.10 m based on a very conservative approach.


    Energy Technology Data Exchange (ETDEWEB)

    Van der Lelie, D.; Reid-Green, J. D.; Stern, E. A.


    We have investigated the feasibility of using natural attenuation methods for ecosystem restoration in New York/New Jersey Harbor. Measurements were made of the most probable number of sulfate-reducing bacteria (SRB) in native sediments and in samples, which had been supplemented with an appropriate electron donor and electron acceptor. The results showed that the activity of the endogenous microbial population in the native sediment was high enough to make possible adequate chemical transformation rates. The bioavailability of the zinc in the sediments was measured using the BIOMET biosensor technique. The bioavailability of the zinc was effectively eliminated following the microbial activities. We concluded that natural attenuation could be used effectively in treating sediments from Newark Bay and surrounding waters and that the resultant materials could likely be used in environmental restoration projects of the type proposed for construction in South Kearny, NJ.

  15. Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury


    Yoon-Kyung Chang; Hyunsu Choi; Jin Young Jeong; Ki-Ryang Na; Kang Wook Lee; Beom Jin Lim; Dae Eun Choi


    Dapagliflozin, a new type of drug used to treat diabetes mellitus (DM), is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Although some studies showed that SGLT2 inhibition attenuated reactive oxygen generation in diabetic kidney the role of SGLT2 inhibition is unknown. We evaluated whether SLT2 inhibition has renoprotective effects in ischemia-reperfusion (IR) models. We evaluated whether dapagliflozin reduces renal damage in IR mice model. In addition, hypoxic HK2 cells were treated wi...

  16. Advanced reconstruction of attenuation maps using SPECT emission data only (United States)

    Salomon, André; Goedicke, Andreas; Aach, Til


    Today, attenuation corrected SPECT, typically performed using CT or Gadolinium line source based transmission scans, is more and more becoming standard in many medical applications. Moreover, the information about the material density distribution provided by these scans is key for other artifact compensation approaches in advanced SPECT reconstruction. Major drawbacks of these approaches are the additional patient radiation and hardware/maintenance costs as well as the additional workflow effort, e.g. if the CT scans are not performed on a hybrid scanner. It has been investigated in the past, whether it is possible to recover this structural information solely from the SPECT scan data. However, the investigated methods often result in noticeable image artifacts due to cross-dependences between attenuation and activity distribution estimation. With the simultaneous reconstruction method presented in this paper, we aim to effectively prevent these typical cross-talk artifacts using a-priori known atlas information of a human body. At first, an initial 3D shape model is coarsely registered to the SPECT data using anatomical landmarks and each organ structure within the model is identified with its typical attenuation coefficient. During the iterative reconstruction based on a modified ML-EM scheme, the algorithm simultaneously adapts both, the local activity estimation and the 3D shape model in order to improve the overall consistency between measured and estimated sinogram data. By explicitly avoiding topology modifications resulting in a non-anatomical state, we ensure that the estimated attenuation map remains realistic. Several tests with simulated as well as real patient SPECT data were performed to test the proposed algorithm, which demonstrated reliable convergence behaviour in both cases. Comparing the achieved results with available reference data, an overall good agreement for both cold as well as hot activity regions could be observed (mean deviation: -5.98%).

  17. Genetically attenuated Trypanosoma cruzi parasites as a potential vaccination tool



    Chagas disease is the clinical manifestation of the infection produced by the parasite Trypanosoma cruzi. Currently there is no vaccine to prevent this disease and the protection attained with vaccines containing non-replicating parasites is limited. Genetically attenuated trypanosomatid parasites can be obtained by deletion of selected genes. Gene deletion takes advantage of the fact that this parasite can undergo homologous recombination between endogenous and foreign DNA sequences artifici...

  18. Mesenchymal dental pulp cells attenuate dentin resorption in homeostasis. (United States)

    Zheng, Y; Chen, M; He, L; Marão, H F; Sun, D M; Zhou, J; Kim, S G; Song, S; Wang, S L; Mao, J J


    Dentin in permanent teeth rarely undergoes resorption in development, homeostasis, or aging, in contrast to bone that undergoes periodic resorption/remodeling. The authors hypothesized that cells in the mesenchymal compartment of dental pulp attenuate osteoclastogenesis. Mononucleated and adherent cells from donor-matched rat dental pulp (dental pulp cells [DPCs]) and alveolar bone (alveolar bone cells [ABCs]) were isolated and separately cocultured with primary rat splenocytes. Primary splenocytes readily aggregated and formed osteoclast-like cells in chemically defined osteoclastogenesis medium with 20 ng/mL of macrophage colony-stimulating factor (M-CSF) and 50 ng/mL of receptor activator of nuclear factor κB ligand (RANKL). Strikingly, DPCs attenuated osteoclastogenesis when cocultured with primary splenocytes, whereas ABCs slightly but significantly promoted osteoclastogenesis. DPCs yielded ~20-fold lower RANKL expression but >2-fold higher osteoprotegerin (OPG) expression than donor-matched ABCs, yielding a RANKL/OPG ratio of 41:1 (ABCs:DPCs). Vitamin D3 significantly promoted RANKL expression in ABCs and OPG in DPCs. In vivo, rat maxillary incisors were atraumatically extracted (without any tooth fractures), followed by retrograde pulpectomy to remove DPCs and immediate replantation into the extraction sockets to allow repopulation of the surgically treated root canal with periodontal and alveolar bone-derived cells. After 8 wk, multiple dentin/root resorption lacunae were present in root dentin with robust RANKL and OPG expression. There were areas of dentin resoprtion alternating with areas of osteodentin formation in root dentin surface in the observed 8 wk. These findings suggest that DPCs of the mesenchymal compartment have an innate ability to attenuate osteoclastogenesis and that this innate ability may be responsible for the absence of dentin resorption in homeostasis. Mesenchymal attenuation of dentin resorption may have implications in internal

  19. The Attribute for Hydrocarbon Prediction Based on Attenuation (United States)

    Hermana, Maman; Harith, Z. Z. T.; Sum, C. W.; Ghosh, D. P.


    Hydrocarbon prediction is a crucial issue in the oil and gas industry. Currently, the prediction of pore fluid and lithology are based on amplitude interpretation which has the potential to produce pitfalls in certain conditions of reservoir. Motivated by this fact, this work is directed to find out other attributes that can be used to reduce the pitfalls in the amplitude interpretation. Some seismic attributes were examined and studies showed that the attenuation attribute is a better attribute for hydrocarbon prediction. Theoretically, the attenuation mechanism of wave propagation is associated with the movement of fluid in the pore; hence the existence of hydrocarbon in the pore will be represented by attenuation attribute directly. In this paper we evaluated the feasibility of the quality factor ratio of P-wave and S-wave (Qp/Qs) as hydrocarbon indicator using well data and also we developed a new attribute based on attenuation for hydrocarbon prediction -- Normalized Energy Reduction Stack (NERS). To achieve these goals, this work was divided into 3 main parts; estimating the Qp/Qs on well log data, testing the new attribute in the synthetic data and applying the new attribute on real data in Malay Basin data. The result show that the Qp/Qs is better than Poisson's ratio and Lamda over Mu as hydrocarbon indicator. The curve, trend analysis and contrast of Qp/Qs is more powerful at distinguishing pore fluid than Poisson ratio and Lamda over Mu. The NERS attribute was successful in distinguishing the hydrocarbon from brine on synthetic data. Applying this attribute on real data on Malay basin, the NERS attribute is qualitatively conformable with the structure and location where the gas is predicted. The quantitative interpretation of this attribute for hydrocarbon prediction needs to be investigated further.

  20. Arsenic cycling in hydrocarbon plumes: secondary effects of natural attenuation (United States)

    Cozzarelli, Isabelle M.; Schreiber, Madeline E.; Erickson, Melinda L.; Ziegler, Brady A.


    Monitored natural attenuation is widely applied as a remediation strategy at hydrocarbon spill sites. Natural attenuation relies on biodegradation of hydrocarbons coupled with reduction of electron acceptors, including solid phase ferric iron (Fe(III)). Because arsenic (As) adsorbs to Fe-hydroxides, a potential secondary effect of natural attenuation of hydrocarbons coupled with Fe(III) reduction is a release of naturally occurring As to groundwater. At a crude-oil-contaminated aquifer near Bemidji, Minnesota, anaerobic biodegradation of hydrocarbons coupled to Fe(III) reduction has been well documented. We collected groundwater samples at the site annually from 2009 to 2013 to examine if As is released to groundwater and, if so, to document relationships between As and Fe inside and outside of the dissolved hydrocarbon plume. Arsenic concentrations in groundwater in the plume reached 230 µg/L, whereas groundwater outside the plume contained less than 5 µg/L As. Combined with previous data from the Bemidji site, our results suggest that (1) naturally occurring As is associated with Fe-hydroxides present in the glacially derived aquifer sediments; (2) introduction of hydrocarbons results in reduction of Fe-hydroxides, releasing As and Fe to groundwater; (3) at the leading edge of the plume, As and Fe are removed from groundwater and retained on sediments; and (4) downgradient from the plume, patterns of As and Fe in groundwater are similar to background. We develop a conceptual model of secondary As release due to natural attenuation of hydrocarbons that can be applied to other sites where an influx of biodegradable organic carbon promotes Fe(III) reduction.

  1. Evaluation of satellite derived spectral diffuse attenuation coefficients

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, T.; Talaulikar, M.; Desa, E.; Mascarenhas, A.A.M.Q.; Matondkar, S.G.P.

    Conference on Harbour and Ocean Engineering, 12-14, Dec. 2007, at NITK, Surathkal 116 EVALUATION OF SATELLITE DERIVED SPECTRAL DIFFUSE ATTENUATION COEFFICIENTS T.Suresh, Madhubala Talaulikar, Elgar Desa, Antonio Mascaranhas, S.G. Prabhu Matondkar... evaluated the satellite-derived values using the Root mean Squared Error (RMSE), mean of the absolute percentage difference (apd) (Lee, 2005), mean percent deviation (MPD) and coefficient of determination (r 2 ). The RMSE and apd provide information about...

  2. Interlaboratory comparison of radiation-induced attenuation in optical fibers

    Energy Technology Data Exchange (ETDEWEB)

    Friebele, E.J.; Lyons, P.B.; Blackburn, J.C.; Henschel, H.; Johan, A.; Krinsky, J.A.; Robinson, A.; Schneider, W.; Smith, D.; Taylor, E.W. (Naval Research Lab., Washington, DC (USA); Los Alamos National Lab., NM (USA); Harry Diamond Labs., Adelphi, MD (USA); Fraunhofer-Institut fuer Naturwissenschaftlich-Technische Trendanalysen (INT), Euskirchen (Germany, F.R.); Direction des Recherches, Etudes et Techni


    A comparison of the losses induced in step index multimode, graded index multimode and single mode fibers by pulsed radiation exposure has been made among 12 laboratories over a period of 5 years. The recoveries of the incremental attenuations from 10{sup -9} to 10{sup 1} s are reported. Although a standard set of measurement parameters was attempted, differences between the laboratories are evident; possible origins for these are discussed. 18 refs., 18 figs., 7 tabs.

  3. Synthetic Chemicals with Potential for Natural Attenuation (Postprint) (United States)


    Distribution Code 20: JOURNAL ARTICLES; DTIC USERS ONLY. Document contains color images. Published in Bioremediation Journal 1 (1): 1-9 (1997...Natural attenuation of petroleum hydrocarbons is predictable and self-sustaining because bacteria able to use the contaminants as growth substrates are...petroleum hydrocarbons is predictable and self-sustaining because bacteria able to use the contaminants as growth substrates are widely distributed. In

  4. Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. (United States)

    de Groot, Theun; Sinke, Anne P; Kortenoeven, Marleen L A; Alsady, Mohammad; Baumgarten, Ruben; Devuyst, Olivier; Loffing, Johannes; Wetzels, Jack F; Deen, Peter M T


    To reduce lithium-induced nephrogenic diabetes insipidus (lithium-NDI), patients with bipolar disorder are treated with thiazide and amiloride, which are thought to induce antidiuresis by a compensatory increase in prourine uptake in proximal tubules. However, thiazides induced antidiuresis and alkalinized the urine in lithium-NDI mice lacking the sodium-chloride cotransporter, suggesting that inhibition of carbonic anhydrases (CAs) confers the beneficial thiazide effect. Therefore, we tested the effect of the CA-specific blocker acetazolamide in lithium-NDI. In collecting duct (mpkCCD) cells, acetazolamide reduced the cellular lithium content and attenuated lithium-induced downregulation of aquaporin-2 through a mechanism different from that of amiloride. Treatment of lithium-NDI mice with acetazolamide or thiazide/amiloride induced similar antidiuresis and increased urine osmolality and aquaporin-2 abundance. Thiazide/amiloride-treated mice showed hyponatremia, hyperkalemia, hypercalcemia, metabolic acidosis, and increased serum lithium concentrations, adverse effects previously observed in patients but not in acetazolamide-treated mice in this study. Furthermore, acetazolamide treatment reduced inulin clearance and cortical expression of sodium/hydrogen exchanger 3 and attenuated the increased expression of urinary PGE2 observed in lithium-NDI mice. These results show that the antidiuresis with acetazolamide was partially caused by a tubular-glomerular feedback response and reduced GFR. The tubular-glomerular feedback response and/or direct effect on collecting duct principal or intercalated cells may underlie the reduced urinary PGE2 levels with acetazolamide, thereby contributing to the attenuation of lithium-NDI. In conclusion, CA activity contributes to lithium-NDI development, and acetazolamide attenuates lithium-NDI development in mice similar to thiazide/amiloride but with fewer adverse effects.

  5. Attenuation Analysis and Acoustic Pressure Levels for Combined Absorptive Mufflers

    Directory of Open Access Journals (Sweden)

    Ovidiu Vasile


    Full Text Available The paper describes the pressure-wave propagation in a muffler for an internal combustion engine in case of two combined mufflers geometry. The approach is generally applicable to analyzing the damping of propagation of harmonic pressure waves. The paper purpose is to show finite elements analysis of both inductive and resistive damping in pressure acoustics. The main output is the attenuation and acoustic pressure levels for the frequency range 50 Hz–3000 Hz.

  6. Mode-dependent attenuation of optical fibers: excess loss. (United States)

    Olshansky, R; Nolan, D A


    A theory is presented for calculating the excess loss produced by random perturbations of optical fibers. The theory is applicable to perturbations whose longitudinal spatial frequencies are below the range required for mode coupling. To illustrate the method, losses due to diameter variations are calculated for the case of a step-index optical fiber. The diameter variations are found to produce a strong attenuation of the higher order modes. The total excess loss is approximately wavelength independent.

  7. Deduction of static surface roughness from complex excess attenuation. (United States)

    Nichols, Andrew; Attenborough, Keith; Taherzadeh, Shahram


    Data for complex excess attenuation have been used to determine the effective surface admittance and hence characteristic roughness size of a surface comprising a random distribution of semi-cylindrical rods on an acoustically hard plane. The inversion for roughness size is based on a simplified boss model. The technique is shown to be effective to within 4%, up to a threshold roughness packing density of 32%, above which the interaction between scattering elements appears to exceed that allowed by the model.

  8. Towards ISS disturbance attenuation for randomly switched systems

    CERN Document Server

    Chatterjee, Debasish


    We are concerned with input-to-state stability (ISS) of randomly switched systems. We provide preliminary results dealing with sufficient conditions for stochastic versions of ISS for randomly switched systems without control inputs, and with the aid of universal formulae we design controllers for ISS-disturbance attenuation when control inputs are present. Two types of switching signals are considered: the first is characterized by a statistically slow-switching condition, and the second by a class of semi-Markov processes.

  9. Peripheral δ-opioid receptors attenuate the exercise pressor reflex. (United States)

    Leal, Anna K; Yamauchi, Katsuya; Kim, Joyce; Ruiz-Velasco, Victor; Kaufman, Marc P


    In rats with ligated femoral arteries, the exercise pressor reflex is exaggerated, an effect that is attenuated by stimulation of peripheral μ-opioid receptors on group IV metabosensitive afferents. In contrast, δ-opioid receptors are expressed mostly on group III mechanosensitive afferents, a finding that prompted us to determine whether stimulation of these opioid receptors could also attenuate the exaggerated exercise pressor reflex in "ligated" rats. We found femoral arterial injection of [D-Pen2,D-Pen5]enkephalin (DPDPE; 1.0 μg), a δ-opioid agonist, significantly attenuated the pressor and cardioaccelerator components of the exercise pressor reflex evoked by hindlimb muscle contraction in both rats with ligated and patent femoral arteries. DPDPE significantly decreased the pressor responses to muscle mechanoreflex activation, evoked by tendon stretch, in ligated rats only. DPDPE (1.0 μg) had no effect in either group on the pressor and cardioaccelerator responses to capsaicin (0.2 μg), which primarily stimulates group IV afferents. DPDPE (1.0 μg) had no effect on the pressor and cardioaccelerator responses to lactic acid (24 mM), which stimulates group III and IV afferents, in rats with patent femoral arteries but significantly decreased the pressor response in ligated rats. Western blots revealed the amount of protein comprising the δ-opioid receptor was greater in dorsal root ganglia innervating hindlimbs with ligated femoral arteries than in dorsal root ganglia innervating hindlimbs with patent femoral arteries. Our findings support the hypothesis that stimulation of δ-opioid receptors on group III afferents attenuated the exercise pressor reflex.

  10. Caffeine attenuates scopolamine-induced memory impairment in humans. (United States)

    Riedel, W; Hogervorst, E; Leboux, R; Verhey, F; van Praag, H; Jolles, J


    Caffeine consumption can be beneficial for cognitive functioning. Although caffeine is widely recognized as a mild CNS stimulant drug, the most important consequence of its adenosine antagonism is cholinergic stimulation, which might lead to improvement of higher cognitive functions, particularly memory. In this study, the scopolamine model of amnesia was used to test the cholinergic effects of caffeine, administered as three cups of coffee. Subjects were 16 healthy volunteers who received 250 mg caffeine and 2 mg nicotine separately, in a placebo-controlled double-blind cross-over design. Compared to placebo, nicotine attenuated the scopolamine-induced impairment of storage in short-term memory and attenuated the scopolamine-induced slowing of speed of short-term memory scanning. Nicotine also attenuated the scopolamine-induced slowing of reaction time in a response competition task. Caffeine attenuated the scopolamine-induced impairment of free recall from short- and long-term memory, quality and speed of retrieval from long-term memory in a word learning task, and other cognitive and non-cognitive measures, such as perceptual sensitivity in visual search, reading speed, and rate of finger-tapping. On the basis of these results it was concluded that caffeine possesses cholinergic cognition enhancing properties. Caffeine could be used as a control drug in studies using the scopolamine paradigm and possibly also in other experimental studies of cognitive enhancers, as the effects of a newly developed cognition enhancing drug should at least be superior to the effects of three cups of coffee.

  11. Simulating atmospheric free-space optical propagation: rainfall attenuation (United States)

    Achour, Maha


    With recent advances and interest in Free-Space Optics (FSO) for commercial deployments, more attention has been placed on FSO weather effects and the availability of global weather databases. The Meteorological Visual Range (Visibility) is considered one of the main weather parameters necessary to estimate FSO attenuation due to haze, fog and low clouds. Proper understanding of visibility measurements conducted throughout the years is essential. Unfortunately, such information is missing from most of the databases, leaving FSO players no choice but to use the standard visibility equation based on 2% contrast and other assumptions on the source luminance and its background. Another challenge is that visibility is measured using the visual wavelength of 550 nm. Extrapolating the measured attenuations to longer infrared wavelengths is not trivial and involves extensive experimentations. Scattering of electromagnetic waves by spherical droplets of different sizes is considered to simulate FSO scattering effects. This paper serves as an introduction to a series of publications regarding simulation of FSO atmospheric propagation. This first part focuses on attenuation due to rainfall. Additional weather parameters, such as rainfall rate, temperature and relative humidity are considered to effectively build the rain model. Comparison with already published experimental measurement is performed to validate the model. The scattering cross section due to rain is derived from the density of different raindrop sizes and the raindrops fall velocity is derived from the overall rainfall rate. Absorption due the presence of water vapor is computed using the temperature and relative humidity measurements.

  12. Gender differences in real-world hearing protector attenuation. (United States)

    Abel, S M; Alberti, P W; Rokas, D


    This research investigated the possibility of differences in real-world attenuation attributable to gender. A total of 160 subjects, 80 males and 80 females, under the age of 45 years, and with normal hearing, were tested. Subjects were assigned to four hearing protector categories with the restriction that there were 20 males and 20 females in each group. The devices chosen for study were the E-A-R expandable foam plug, the Willson Sound Silencer premolded vinyl plug with double flange, the Bilsom Soft polyethylene encapsulated glass fiber plug, and the MSA Ear Defender (V-51R) premolded vinyl plug with single flange. Binaural headphone detection thresholds were measured in quiet with the open ear, and subsequently with protectors fitted binaurally for one-third octave noise bands centered at 250, 500, 1000, 3150 and 6300 Hz. The results indicated that attenuation scores achieved by females were less than those observed for males when the device was sold in only one size. Apart from the question of adequate sizing, for two of the insert protectors studied, mean achieved attenuation fell short of the manufacturer's specifications by as much as 18 dB, for particular frequencies tested. The relatively wide variation in scores observed for all four protectors in spite of experimenter-fit could not be accounted for by differences in either hearing threshold across subjects or by size of plug fit, for those devices available in several sizes.

  13. Ultrasound attenuation as a quantitative measure of fracture healing (United States)

    Gheduzzi, Sabina; Humphrey, Victor F.; Dodd, Simon P.; Cunningham, James L.; Miles, Anthony W.


    The monitoring of fracture healing still relies upon the judgment of callus formation and on the manual assessment of the stiffness of the fracture. A diagnostic tool capable of quantitatively measuring healing progression of a fracture would allow the fine-tuning of the treatment regime. Ultrasound attenuation measurements were adopted as a possible method of assessing the healing process in human long bones. The method involves exciting ultrasonic waves at 200 kHz in the bone and measuring the reradiation along the bone and across the fracture zone. Seven cadaveric femora were tested in vitro in intact form and after creating a transverse fracture by sawing through the cortex. The effects of five different fracture types were investigated. A partial fracture, corresponding to a 50% cut through the cortex, a closed fracture, and fractures of widths varying between 1, 2, and 4 mm were investigated. The introduction of a fracture was found to produce a dramatic effect on the amplitude of the signal. Ultrasound attenuation was found to be sensitive to the presence of a fracture, even when the fracture was well reduced. It would therefore appear feasible to adopt attenuation across a fracture as a quantitative measurement of fracture healing.

  14. Genetically attenuated Trypanosoma cruzi parasites as a potential vaccination tool. (United States)

    Pérez Brandan, Cecilia; Basombrío, Miguel Ángel


    Chagas disease is the clinical manifestation of the infection produced by the parasite Trypanosoma cruzi. Currently there is no vaccine to prevent this disease and the protection attained with vaccines containing non-replicating parasites is limited. Genetically attenuated trypanosomatid parasites can be obtained by deletion of selected genes. Gene deletion takes advantage of the fact that this parasite can undergo homologous recombination between endogenous and foreign DNA sequences artificially introduced in the cells. This approach facilitated the discovery of several unknown gene functions, as well as allowing us to speculate about the potential for genetically attenuated live organisms as experimental immunogens. Vaccination with live attenuated parasites has been used effectively in mice to reduce parasitemia and histological damage, and in dogs, to prevent vector-delivered infection in the field. However, the use of live parasites as immunogens is controversial due to the risk of reversion to a virulent phenotype. Herein, we present our results from experiments on genetic manipulation of two T. cruzi strains to produce parasites with impaired replication and infectivity, and using the mutation of the dhfr-ts gene as a safety device against reversion to virulence.

  15. Frequency dependent Lg attenuation in south-central Alaska (United States)

    McNamara, D.E.


    The characteristics of seismic energy attenuation are determined using high frequency Lg waves from 27 crustal earthquakes, in south-central Alaska. Lg time-domain amplitudes are measured in five pass-bands and inverted to determine a frequency-dependent quality factor, Q(f), model for south-central Alaska. The inversion in this study yields the frequency-dependent quality factor, in the form of a power law: Q(f) = Q0fη = 220(±30) f0.66(±0.09) (0.75≤f≤12Hz). The results from this study are remarkably consistent with frequency dependent quality factor estimates, using local S-wave coda, in south-central Alaska. The consistency between S-coda Q(f) and Lg Q(f) enables constraints to be placed on the mechanism of crustal attenuation in south-central Alaska. For the range of frequencies considered in this study both scattering and intrinsic attenuation mechanisms likely play an equal role.

  16. Creating a collimated ultrasound beam in highly attenuating fluids. (United States)

    Raeymaekers, Bart; Pantea, Cristian; Sinha, Dipen N


    We have devised a method, based on a parametric array concept, to create a low-frequency (300-500 kHz) collimated ultrasound beam in fluids highly attenuating to sound. This collimated beam serves as the basis for designing an ultrasound visualization system that can be used in the oil exploration industry for down-hole imaging in drilling fluids. We present the results of two different approaches to generating a collimated beam in three types of highly attenuating drilling mud. In the first approach, the drilling mud itself was used as a nonlinear mixing medium to create a parametric array. However, the short absorption length in mud limits the mixing length and, consequently, the resulting beam is weak and broad. In the second improved approach, the beam generation process was confined to a separate "frequency mixing tube" that contained an acoustically non-linear, low attenuation medium (e.g., water) that allowed establishing a usable parametric array in the mixing tube. A low-frequency collimated beam was thus created prior to its propagation into the drilling fluid. Using the latter technique, the penetration depth of the low frequency ultrasound beam in the drilling fluid was significantly extended. We also present measurements of acoustic nonlinearity in various types of drilling mud.

  17. Attenuation of S wave in the crust of Ordos massif

    Institute of Scientific and Technical Information of China (English)

    LIU Hong-gui; CHUO Yong-qing; CHEN Shu-qing; JIN Chun-hua


    We presented attenuation characteristics of S waves in the crust of Ordos massif. Using 487 pieces of digital oscillograms of 19 seismic events recorded by 32 seismologic stations located on Ordos massif and its surroundings, we have calculated the parameter of three-segment geometric attenuation and give the relation of inelastic attenuation Q value with frequency in the crust of Ordos massif, site responses of 32 stations, and source parameters of 19 events by the genetic algorithm. The results indicate that Q value (at 1 Hz) of S-wave in the crust of Ordos massif is much larger than that in the geologically active tectonic region. The site responses of the 32 stations in the high-frequency section do not show clear amplification effect except one or two stations, while in the low-frequency section, there is difference among the stations. The logarithmic value of seismic moment and the magnitude ML of 19 seismic events has a very good linear relationship.

  18. Clinical evaluation strategies for a live attenuated tetravalent dengue vaccine. (United States)

    Precioso, Alexander Roberto; Palacios, Ricardo; Thomé, Beatriz; Mondini, Gabriella; Braga, Patrícia; Kalil, Jorge


    Butantan Institute is a public Brazilian biomedical research-manufacturer center affiliated to the São Paulo State Secretary of Health. Currently, Butantan is one of the main public producers of vaccines, antivenoms, and antitoxins in Latin America. The partnership between Butantan and the National Institutes of Health (NIH) of the United Sates has been one of the longest and most successful partnerships in the development and manufacturing of new vaccines. Recently, Butantan Institute has developed and manufactured a lyophilized tetravalent live attenuated dengue vaccine with the four dengue viruses attenuated and licensed from the Laboratory of Infectious Diseases at The National Institutes of Allergy and Infectious Diseases (LID/NIAID/NIH). The objective of this paper is to describe the clinical evaluation strategies of a live attenuated tetravalent dengue vaccine (Butantan-DV) developed and manufactured by Butantan Institute. These clinical strategies will be used to evaluate the Butantan-DV Phase III trial to support the Butantan-DV licensure for protection against any symptomatic dengue caused by any serotype in people aged 2 to 59 years.

  19. Multicomponent seismic noise attenuation with multivariate order statistic filters (United States)

    Wang, Chao; Wang, Yun; Wang, Xiaokai; Xun, Chao


    The vector relationship between multicomponent seismic data is highly important for multicomponent processing and interpretation, but this vector relationship could be damaged when each component is processed individually. To overcome the drawback of standard component-by-component filtering, multivariate order statistic filters are introduced and extended to attenuate the noise of multicomponent seismic data by treating such dataset as a vector wavefield rather than a set of scalar fields. According to the characteristics of seismic signals, we implement this type of multivariate filtering along local events. First, the optimal local events are recognized according to the similarity between the vector signals which are windowed from neighbouring seismic traces with a sliding time window along each trial trajectory. An efficient strategy is used to reduce the computational cost of similarity measurement for vector signals. Next, one vector sample each from the neighbouring traces are extracted along the optimal local event as the input data for a multivariate filter. Different multivariate filters are optimal for different noise. The multichannel modified trimmed mean (MTM) filter, as one of the multivariate order statistic filters, is applied to synthetic and field multicomponent seismic data to test its performance for attenuating white Gaussian noise. The results indicate that the multichannel MTM filter can attenuate noise while preserving the relative amplitude information of multicomponent seismic data more effectively than a single-channel filter.

  20. A robust polynomial principal component analysis for seismic noise attenuation (United States)

    Wang, Yuchen; Lu, Wenkai; Wang, Benfeng; Liu, Lei


    Random and coherent noise attenuation is a significant aspect of seismic data processing, especially for pre-stack seismic data flattened by normal moveout correction or migration. Signal extraction is widely used for pre-stack seismic noise attenuation. Principle component analysis (PCA), one of the multi-channel filters, is a common tool to extract seismic signals, which can be realized by singular value decomposition (SVD). However, when applying the traditional PCA filter to seismic signal extraction, the result is unsatisfactory with some artifacts when the seismic data is contaminated by random and coherent noise. In order to directly extract the desired signal and fix those artifacts at the same time, we take into consideration the amplitude variation with offset (AVO) property and thus propose a robust polynomial PCA algorithm. In this algorithm, a polynomial constraint is used to optimize the coefficient matrix. In order to simplify this complicated problem, a series of sub-optimal problems are designed and solved iteratively. After that, the random and coherent noise can be effectively attenuated simultaneously. Applications on synthetic and real data sets note that our proposed algorithm can better suppress random and coherent noise and have a better performance on protecting the desired signals, compared with the local polynomial fitting, conventional PCA and a L1-norm based PCA method.

  1. Dust Attenuation in High Redshift Galaxies -- 'Diamonds in the Sky'

    CERN Document Server

    Scoville, Nick; Capak, Peter; Kakazu, Yuko; Li, Gongjie; Steinhardt, Charles


    We use observed optical to near infrared spectral energy distributions (SEDs) of 266 galaxies in the COSMOS survey to derive the wavelength dependence of the dust attenuation at high redshift. All of the galaxies have spectroscopic redshifts in the range z = 2 to 6.5. The presence of the CIV absorption feature, indicating that the rest-frame UV-optical SED is dominated by OB stars, is used to select objects for which the intrinsic, unattenuated spectrum has a well-established shape. Comparison of this intrinsic spectrum with the observed broadband photometric SED then permits derivation of the wavelength dependence of the dust attenuation. The derived dust attenuation curve is similar in overall shape to the Calzetti curve for local starburst galaxies. We also see the 2175 \\AA~bump feature which is present in the Milky Way and LMC extinction curves but not seen in the Calzetti curve. The bump feature is commonly attributed to graphite or PAHs. No significant dependence is seen with redshift between sub-sample...

  2. High Attenuation Rate for Shallow, Small Earthquakes in Japan (United States)

    Si, Hongjun; Koketsu, Kazuki; Miyake, Hiroe


    We compared the attenuation characteristics of peak ground accelerations (PGAs) and velocities (PGVs) of strong motion from shallow, small earthquakes that occurred in Japan with those predicted by the equations of Si and Midorikawa (J Struct Constr Eng 523:63-70, 1999). The observed PGAs and PGVs at stations far from the seismic source decayed more rapidly than the predicted ones. The same tendencies have been reported for deep, moderate, and large earthquakes, but not for shallow, moderate, and large earthquakes. This indicates that the peak values of ground motion from shallow, small earthquakes attenuate more steeply than those from shallow, moderate or large earthquakes. To investigate the reason for this difference, we numerically simulated strong ground motion for point sources of M w 4 and 6 earthquakes using a 2D finite difference method. The analyses of the synthetic waveforms suggested that the above differences are caused by surface waves, which are predominant at stations far from the seismic source for shallow, moderate earthquakes but not for shallow, small earthquakes. Thus, although loss due to reflection at the boundaries of the discontinuous Earth structure occurs in all shallow earthquakes, the apparent attenuation rate for a moderate or large earthquake is essentially the same as that of body waves propagating in a homogeneous medium due to the dominance of surface waves.

  3. Static tests of excess ground attenuation at Wallops Flight Center (United States)

    Sutherland, L. C.; Brown, R.


    An extensive experimental measurement program which evaluated the attenuation of sound for close to horizontal propagation over the ground was designed to replicate, under static conditions, results of the flight measurements carried out earlier by NASA at the same site (Wallops Flight Center). The program consisted of a total of 41 measurement runs of attenuation, in excess of spreading and air absorption losses, for one third octave bands over a frequency range of 50 to 4000 Hz. Each run consisted of measurements at 10 locations up to 675 m, from a source located at nominal elevations of 2.5, or 10 m over either a grassy surface or an adjacent asphalt concrete runway surface. The tests provided a total of over 8100 measurements of attenuation under conditions of low wind speed averaging about 1 m/s and, for most of the tests, a slightly positive temperature gradient, averaging about 0.3 C/m from 1.2 to 7 m. The results of the measurements are expected to provide useful experimental background for the further development of prediction models of near grazing incidence sound propagation losses.

  4. Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis (United States)


    Copper sulfate-induced premature senescence (CuSO4-SIPS) consistently mimetized molecular mechanisms of replicative senescence, particularly at the endoplasmic reticulum proteostasis level. In fact, disruption of protein homeostasis has been associated to age-related cell/tissue dysfunction and human disorders susceptibility. Resveratrol is a polyphenolic compound with proved antiaging properties under particular conditions. In this setting, we aimed to evaluate resveratrol ability to attenuate cellular senescence induction and to unravel related molecular mechanisms. Using CuSO4-SIPS WI-38 fibroblasts, resveratrol is shown to attenuate typical senescence alterations on cell morphology, senescence-associated beta-galactosidase activity, and cell proliferation. The mechanisms implicated in this antisenescence effect seem to be independent of senescence-associated genes and proteins regulation but are reliant on cellular proteostasis improvement. In fact, resveratrol supplementation restores copper-induced increased protein content, attenuates BiP level, and reduces carbonylated and polyubiquitinated proteins by autophagy induction. Our data provide compelling evidence for the beneficial effects of resveratrol by mitigating CuSO4-SIPS stressful consequences by the modulation of protein quality control systems. These findings highlight the importance of a balanced cellular proteostasis and add further knowledge on molecular mechanisms mediating resveratrol antisenescence effects. Moreover, they contribute to identifying specific molecular targets whose modulation will prevent age-associated cell dysfunction and improve human healthspan. PMID:28280523

  5. Neuropeptide FF receptors as novel targets for limbic seizure attenuation. (United States)

    Portelli, Jeanelle; Meurs, Alfred; Bihel, Frederic; Hammoud, Hassan; Schmitt, Martine; De Kock, Joery; Utard, Valerie; Humbert, Jean-Paul; Bertin, Isabelle; Buffel, Ine; Coppens, Jessica; Tourwe, Dirk; Maes, Veronique; De Prins, An; Vanhaecke, Tamara; Massie, Ann; Balasubramaniam, Ambikaipakan; Boon, Paul; Bourguignon, Jean-Jacques; Simonin, Frederic; Smolders, Ilse


    Neuropeptide Y (NPY) is a well established anticonvulsant and first-in-class antiepileptic neuropeptide. In this study, the controversial role of NPY1 receptors in epilepsy was reassessed by testing two highly selective NPY1 receptor ligands and a mixed NPY1/NPFF receptor antagonist BIBP3226 in a rat model for limbic seizures. While BIBP3226 significantly attenuated the pilocarpine-induced seizures, neither of the highly selective NPY1 receptor ligands altered the seizure severity. Administration of the NPFF1/NPFF2 receptor antagonist RF9 also significantly attenuated limbic seizure activity. To further prove the involvement of NPFF receptors in these seizure-modulating effects, low and high affinity antagonists for the NPFF receptors were tested. We observed that the low affinity ligand failed to exhibit anticonvulsant properties while the two high affinity ligands significantly attenuated the seizures. Continuous NPFF1 receptor agonist administration also inhibited limbic seizures whereas bolus administration of the NPFF1 receptor agonist was without effect. This suggests that continuous agonist perfusion could result in NPFF1 receptor desensitization and mimic NPFF1 receptor antagonist administration. Our data unveil for the first time the involvement of the NPFF system in the management of limbic seizures.

  6. Adaptation with disturbance attenuation in nonlinear control systems

    Energy Technology Data Exchange (ETDEWEB)

    Basar, T. [Univ. of Illinois, Urbana, IL (United States)


    We present an optimization-based adaptive controller design for nonlinear systems exhibiting parametric as well as functional uncertainty. The approach involves the formulation of an appropriate cost functional that places positive weight on deviations from the achievement of desired objectives (such as tracking of a reference trajectory while the system exhibits good transient performance) and negative weight on the energy of the uncertainty. This cost functional also translates into a disturbance attenuation inequality which quantifies the effect of the presence of uncertainty on the desired objective, which in turn yields an interpretation for the optimizing control as one that optimally attenuates the disturbance, viewed as the collection of unknown parameters and unknown signals entering the system dynamics. In addition to this disturbance attenuation property, the controllers obtained also feature adaptation in the sense that they help with identification of the unknown parameters, even though this has not been set as the primary goal of the design. In spite of this adaptation/identification role, the controllers obtained are not of certainty-equivalent type, which means that the identification and the control phases of the design are not decoupled.

  7. Plasmodium yoelii: induction of attenuated mutants by irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Waki, S.; Yonome, I.; Suzuki, M.


    When erythrocytic forms of Plasmodium yoelii nigeriensis, which is invariably fatal in mice, were exposed to X rays, the dose to reduce surviving parasites to one millionth was 100 gray (10 Krad). A suspension of 5 X 10(6) per ml of parasitized erythrocyte was irradiated at 100 gray, and 0.2 ml aliquots were inoculated into 22 mice. Eleven mice showed patent parasitemia, and in these the growth curves were less steep than that found in nonirradiated parasites. The infections of 8 mice of the 11 were self-resolving, and the attenuated feature of the parasites maintained following a limited number of blood passages. The parasites were slowly growing even in nude mice and cause self-resolving infections in intact mice. BALB/c mice immunized with the attenuated parasites were protected against subsequent challenge infections with the original virulent erythrocytic and sporogonic forms. These findings indicate that attenuated mutants of malaria parasites can be readily induced by this method.

  8. Attenuation Tomography of Sierra Negra Volcano of the Galapagos Archipelago (United States)

    Rodd, R.; Lees, J. M.


    Following relocation of events with the double-difference location algorithm (HypoDD), we apply tomographic methods to extract 3D attenuation models illuminating the plumbing system of the Sierra Negra Caldera of the Galapagos Archipelago. The dataset consists of 1737 events recorded from July 2009 to June 2011 on the 17-station SIGNET broadband seismic array. We use t* spectral decay methods for both P- and S- phases with the clustered locations to highlight locations where significant variations in Q suggest the presence of magma melt. While the presence of a magma sill, at least 2 km depth, is indicated by InSAR and GPS studies, the delineated magma body has not been explored in detail. The lower bound of the proposed magma accumulation is still under question and thus forms the primary target of this research. Melt replenishment and degassing of the magma sill is believed to cause inflation and/or deflation of the caldera floor. Imaging the extent of the magma sill will provide insight into the feeder system and deformation process of the Sierra Negra caldera. Detailed relocation, Qp and Qs inversion, as well as estimates of the scattering attenuation using coda-normalization technique will be presented. The close relationship between seismic attenuation and the thermal state of the magmatic system suggests we can distinguish melt and/or fluid regions within the Sierra Negra plumbing system.

  9. Natural attenuation software (NAS): Assessing remedial strategies and estimating timeframes (United States)

    Mendez, E.; Widdowson, M.; Chapelle, F.; Casey, C.


    Natural Attenuation Software (NAS) is a screening tool to estimate remediation timeframes for monitored natural attenuation (MNA) and to assist in decision-making on the level of source zone treatment in conjunction with MNA using site-specific remediation objectives. Natural attenuation processes that NAS models include are advection, dispersion, sorption, non-aqueous phase liquid (NAPL) dissolution, and biodegradation of either petroleum hydrocarbons or chlorinated ethylenes. Newly-implemented enhancements to NAS designed to maximize the utility of NAS for site managers were observed. NAS has expanded source contaminant specification options to include chlorinated ethanes and chlorinated methanes, and to allow for the analysis of any other user-defined contaminants that may be subject to microbially-mediated transformations (heavy metals, radioisotopes, etc.). Included is the capability to model co-mingled plumes, with constituents from multiple contaminant categories. To enable comparison of remediation timeframe estimates between MNA and specific engineered remedial actions , NAS was modified to incorporate an estimation technique for timeframes associated with pump-and-treat remediation technology for comparison to MNA. This is an abstract of a paper presented at the 8th International In Situ and On-Site Bioremediation Symposium (Baltimore, MD 6/6-9/2005).

  10. An adaptive noise attenuation method for edge and amplitude preservation

    Institute of Scientific and Technical Information of China (English)

    Cai Han-Peng; He Zhen-Hua; Li Ya-Lin; He Guang-Ming; Zou Wen; Zhang Dong-Jun; Liu Pu


    Noise intensity distributed in seismic data varies with different frequencies or frequency bands; thus, noise attenuation on the full-frequency band affects the dynamic properties of the seismic reflection signal and the subsequent seismic data interpretation, reservoir description, hydrocarbon detection, etc. Hence, we propose an adaptive noise attenuation method for edge and amplitude preservation, wherein the wavelet packet transform is used to decompose the full-band seismic signal into multiband data and then process these data using nonlinear anisotropic dip-oriented edge-preservingfi ltering. In the fi ltering, the calculated diffusion tensor from the structure tensor can be exploited to establish the direction of smoothing. In addition, the fault confidence measure and discontinuity operator can be used to preserve the structural and stratigraphic discontinuities and edges, and the decorrelation criteria can be used to establish the number of iterations. These parameters can minimize the intervention and subjectivity of the interpreter, and simplify the application of the proposed method. We applied the proposed method to synthetic and real 3D marine seismic data. We found that the proposed method could be used to attenuate noise in seismic data while preserving the effective discontinuity information and amplitude characteristics in seismic refl ection waves, providing high-quality data for interpretation and analysis such as high-resolution processing, attribute analysis, and inversion.

  11. Finite Difference Numerical Modeling of Gravito-Acoustic Wave Propagation in a Windy and Attenuating Atmosphere (United States)

    Brissaud, Q.; Garcia, R.; Martin, R.; Komatitsch, D.


    The acoustic and gravity waves propagating in the planetary atmospheres have been studied intensively as markers of specific phenomena (tectonic events, explosions) or as contributors to the atmosphere dynamics. To get a better understanding of the physic behind these dynamic processes, both acoustic and gravity waves propagation should be modeled in an attenuating and windy 3D atmosphere from the ground to the upper thermosphere. Thus, In order to provide an efficient numerical tool at the regional or the global scale a high order finite difference time domain (FDTD) approach is proposed that relies on the linearized compressible Navier-Stokes equations (Landau 1959) with non constant physical parameters (density, viscosities and speed of sound) and background velocities (wind). One significant benefit from this code is its versatility. Indeed, it handles both acoustic and gravity waves in the same simulation that enables one to observe correlations between the two. Simulations will also be performed on 2D/3D realistic cases such as tsunamis in a full MSISE-00 atmosphere and gravity-wave generation through atmospheric explosions. Computations are validated by comparison to well-known analytical solutions based on dispersion relations in specific benchmark cases (atmospheric explosion and bottom displacement forcing).


    Directory of Open Access Journals (Sweden)

    Monika Hanáková


    Full Text Available Taxonomies of physics problems serve as useful tools to define and analyze the requirements of pupils and students in solving physics problems and tasks. The connection between taxonomies of educational objectives is important, and these were considered in selecting taxonomies of physics problems. Different approaches to classification are briefly described in this article, as well as the importance of a balance of physics problems in instruction, according to the selected taxonomy. Two taxonomies of physics problems were chosen according to our criteria and then analyzed and described in detail. A strength, weakness, opportunity, and threat SWOT analysis was performed on the tools as well as an example of the use of the tools on a particular physics problem.

  13. Does Moderate Intensity Exercise Attenuate the Postprandial Lipemic and Airway Inflammatory Response to a High-Fat Meal?

    Directory of Open Access Journals (Sweden)

    Stephanie P. Kurti


    Full Text Available We investigated whether an acute bout of moderate intensity exercise in the postprandial period attenuates the triglyceride and airway inflammatory response to a high-fat meal (HFM compared to remaining inactive in the postprandial period. Seventeen (11 M/6 F physically active (≥150 min/week of moderate-vigorous physical activity (MVPA subjects were randomly assigned to an exercise (EX; 60% VO2peak or sedentary (CON condition after a HFM (10 kcal/kg, 63% fat. Blood analytes and airway inflammation via exhaled nitric oxide (eNO were measured at baseline, and 2 and 4 hours after HFM. Airway inflammation was assessed with induced sputum and cell differentials at baseline and 4 hours after HFM. Triglycerides doubled in the postprandial period (~113 ± 18%, P<0.05, but the increase did not differ between EX and CON. Percentage of neutrophils was increased 4 hours after HFM (~17%, but the increase did not differ between EX and CON. Exhaled nitric oxide changed nonlinearly from baseline to 2 and 4 hours after HFM (P<0.05, η2=0.36. Our findings suggest that, in active individuals, an acute bout of moderate intensity exercise does not attenuate the triglyceride or airway inflammatory response to a high-fat meal.

  14. Empirical Relations for Optical Attenuation Prediction from Liquid Water Content of Fog

    Directory of Open Access Journals (Sweden)

    M. S. Khan


    Full Text Available Simultaneous measurements of the liquid water content (LWC and optical attenuation have been analyzed to predict optical attenuation caused by fog particles. Attenuation has been measured at two different wavelengths, 830 nm and 1550 nm, across co-located links. Five months measured data have been processed to assess power-law empirical models, which estimate optical attenuation from the LWC. The proposed models are compared with other published models and are demonstrated to perform sufficiently well to predict optical attenuation if the LWC values are available.

  15. MR constrained simultaneous reconstruction of activity and attenuation maps in brain TOF-PET/MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Mehranian, Abolfazl; Zaidi, Habib [Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva (Switzerland)


    The maximum likelihood estimation of attenuation and activity (MLAA) algorithm has been proposed to jointly estimate activity and attenuation from emission data only. Salomon et al employed the MLAA to estimate activity and attenuation from time-of-flight PET data with spatial MR prior information on attenuation. Recently, we proposed a novel algorithm to impose both spatial and statistical constraints on attenuation estimation within the MLAA algorithm using Dixon MR images and a constrained Gaussian mixture model (GMM). In this study, we compare the proposed algorithm with MLAA and MLAA-Salomon in brain TOF-PET/MR imaging.

  16. Polymerase Mechanism-Based Method of Viral Attenuation (United States)

    Lee, Cheri A.; August, Avery; Arnold, Jamie J.; Cameron, Craig E.


    Vaccines remain the most effective way of preventing infection and spread of infectious diseases. These prophylactics have been used for centuries but still to this day only three main design strategies exist: (1) live attenuated virus (LAV) vaccines, (2) killed or inactivated virus vaccines, (3) and subunit vaccines of the three, the most efficacious vaccines remain LAVs. LAVs replicate in relevant tissues, elicit strong cellular and humoral responses, and often confer lifelong immunity. While this vaccine strategy has produced the majority of successful vaccines in use today, there are also important safety concerns to consider with this approach. In the past, the development of LAVs has been empirical. Blind passage of viruses in various cell types results in the accumulation of multiple attenuating mutations leaving the molecular mechanisms of attenuation unknown. Also, due to the high error rate of RNA viruses and selective pressures of the host environment, these LAVs, derived from such viruses, can potentially revert back to wild-type virulence. This not only puts the vaccinee at risk, but if shed can put those that are unvaccinated at risk as well. While these vaccines have been successful there still remains a need for a rational design strategy by which to create additional LAVs. One approach for rational vaccine design involves increasing the fidelity of the viral RdRp. Increased fidelity decreases the viral mutational frequency thereby reducing the genetic variation the virus needs in order to evade the host imposed bottlenecks to infection. While polymerase mutants exist which decrease viral mutation frequency the mutations are not in conserved regions of the polymerase, which doesn’t lend itself toward using a common mutant approach toward developing a universal vaccine strategy for all RNA viruses. We have identified a conserved lysine residue in the active site of the PV RdRp that acts as a general acid during nucleotide incorporation. Mutation

  17. Comparison of Reg. Guide 1.99 fluence attenuation methods

    Energy Technology Data Exchange (ETDEWEB)

    Jones, E.N. [TransWare Enterprises Inc., 1565 Mediterranean Dr., Sycamore, IL 60178 (United States)


    U.S. Regulatory Guide 1.99 Revision 2 (U.S. Nuclear Regulatory Commission, 1988, 'Radiation Embrittlement of Reactor Vessel Materials,' Regulatory Guide 1.99, Revision 2, Washington, D.C.) provides for the use of two substantially different methods for determining through-wall fluence in nuclear reactor pressure vessels. One method is a generic attenuation curve based on a simplistic exponential decay equation. Partly due to the simplicity of its application, the generic attenuation method is predominantly used for licensing calculations. However, it has a limitation in that at increasing distances away from the core belt-line, it becomes increasingly less accurate because it cannot account for neutron streaming effects in the cavity region surrounding the pressure vessel. The other attenuation method is based on a displacement per atom (dpa) calculation specific to the reactor vessel structure. The dpa method provides a more accurate representation of fluence attenuation through the reactor pressure vessel (RPV) wall at all elevations of the pressure vessel because it does account for neutron streaming in the cavity region. A requirement for using the dpa method, however, is an accurate flux solution through the RPV wall. This requirement has limited the use of traditional transport methods, such as discrete ordinates, that are limited by their treatment of cavity regions (i.e., air) outside the pressure vessel wall. TransWare Enterprises, under the sponsorship of EPRI and BWRVIR has developed an advanced three-dimensional transport methodology capable of producing fully converged flux solutions throughout the entire reactor system, including in the cavity region and primary shield structures. This methodology provides an accurate and reliable determination of through-wall fluence in boiling water reactor (BWR) and pressurized water reactor (PWR) pressure vessels, thus allowing the dpa method to be implemented with high reliability. Using this advanced 3

  18. Physics and Physics Education at Clarion University (United States)

    Aravind, Vasudeva

    Clarion University is located in the rolling hills of western Pennsylvania. We are a primarily undergraduate public institution serving about 6000 students. We graduate students who take different career paths, one of them being teaching physics at high schools. Since educating teachers of tomorrow requires us to introduce currently trending, research proven pedagogical methods, we incorporate several aspects of physics pedagogies such as peer instruction, flipped classroom and hands on experimentation in a studio physics lab format. In this talk, I discuss some of our projects on physics education, and seek to find potential collaborators interested in working along similar lines.

  19. Physics For All -- yes, it's real physics (United States)

    Eisenkraft, Arthur


    Can ``all'' students learn ``real'' physics? We want to provide instruction to a wider segment of the population including those students who will not go into STEM (Science, Technology, Engineering, Math) careers. We also want to maintain the integrity of physics, challenge all students, and not compromise the rigor of our courses. Accomplishing this requires a research guided approach to instruction, curriculum and assessment. Physics First and Physics for All have become a success story for thousands of students in urban, suburban, and rural districts. At the same time, the International Physics Olympiad and other competitions have raised the expectation of what the most motivated students can achieve. Many physics educators are exploring ways to set higher goals for our most gifted students while also providing physics instruction to students previously excluded from our physics classes. Many of the same issues that K-12 educators are struggling with are equally important to the college community as colleges try to educate both future physicists and an educated citizenry. Great novels and symphonies are accessible to people of different backgrounds and levels of expertise. We should develop strategies that enable us to share an understanding of physics with all students because everyone deserves an opportunity to reflect on the wondrous workings of our universe.

  20. Physical electronics handbook of vacuum physics

    CERN Document Server

    Beck, A H


    Handbook of Vacuum Physics, Volume 2, Physical Electronics, discusses the fundamentals of electric discharges in gases. Electrical discharges in gases is used generically to denote the passage of electricity through a gas and implicitly embraces the wide variety of physical phenomena which accompany such a discharge of electricity. The discharge currents may be as small as 10-16A in certain ionization growth studies, or be as large as megamperes in thermonuclear and plasma physics studies. Key topics discussed include collision phenomena in gases; surface phenomena and transport of charged par

  1. Physical Therapy (For Parents) (United States)

    ... Old Feeding Your 1- to 2-Year-Old Physical Therapy KidsHealth > For Parents > Physical Therapy A A A en español Terapia física Physical Therapy Basics Doctors often recommend physical therapy (PT) for ...

  2. Physics and theology (United States)

    Polkinghorne, John


    The role of theology in relation to science is not to try to tell physics how to answer its own proper questions. We have every reason to believe that physics questions will eventually receive physics answers. However there are meaningful and necessary questions which arise from considering the results of physics but which exceed its selflimited power to address.

  3. Medical Physics Data Book, (United States)

    The Medical Physics Data Book is a collection of physical and chemical data useful in medical physics . The information has been extracted from other...ionizing Radiation. Carried out by the Medical Physics Data Group of the American Association of Physicists in Medicine, this compilation is meant to

  4. History of Medical Physics. (United States)

    Laughlin, John S.


    Traces the development of basic radiation physics that underlies much of today's medical physics and looks separately at the historical development of two major subfields of medical physics: radiation therapy and nuclear medicine. Indicates that radiation physics has made important contributions to solving biomedical problems in medical…

  5. The physics companion

    CERN Document Server

    Fischer-Cripps, Anthony C


    Updated and expanded with new topics, The Physics Companion, 2nd Edition offers a unique and educational approach to learning physics at a level suitable for first-year science students. This new edition expands the presentation to include senior topics, such as statistical mechanics, quantum physics, and nuclear physics.

  6. Doll's House Physics (United States)

    Kibble, Bob


    School physics rarely stands still for long. Environmental physics is now an option in some post-16 courses in England. The physics of environments, and in particular the built environment, offers a recognizable context in which to see the applications of physics at work. This article considers how a model doll's house might be used to help…

  7. Are dusty galaxies blue? Insights on UV attenuation from dust-selected galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Casey, C. M.; Cooray, A. [Department of Physics and Astronomy, University of California, Irvine, Irvine, CA 92697 (United States); Scoville, N. Z. [California Institute of Technology, 1216 East California Boulevard, Pasadena, CA 91125 (United States); Sanders, D. B.; Lee, N. [Institute for Astronomy, University of Hawai' i, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Finkelstein, S. L. [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States); Capak, P. [Spitzer Science Center, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125 (United States); Conley, A. [Center for Astrophysics and Space Astronomy 389-UCB, University of Colorado, Boulder, CO 80309 (United States); De Zotti, G. [Osservatorio Astronomico di Padova, Vicolo dell' Osservatorio 2, I-35122 Padova (Italy); Farrah, D. [Department of Physics, Virginia Tech, Blacksburg, VA 24061 (United States); Fu, H. [Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52242 (United States); Le Floc' h, E. [CEA-Saclay, Orme des Merisiers, bât. 709, F-91191 Gif-sur-Yvette Cedex (France); Ilbert, O. [Aix Marseille Université, CNRS, Laboratoire d' Astrophysique de marseille, UMR 7326, F-13388 Marseille (France); Ivison, R. J. [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh, EH9 3HJ (United Kingdom); Takeuchi, T. T. [Nagoya University, Division of Particle and Astrophysical Science, Furo-cho, Chikusa-ku, Nagoya 464-8602 (Japan)


    Galaxies' rest-frame ultraviolet (UV) properties are often used to directly infer the degree to which dust obscuration affects the measurement of star formation rates (SFRs). While much recent work has focused on calibrating dust attenuation in galaxies selected at rest-frame ultraviolet wavelengths, locally and at high-z, here we investigate attenuation in dusty, star forming galaxies (DSFGs) selected at far-infrared wavelengths. By combining multiwavelength coverage across 0.15-500 μm in the COSMOS field, in particular making use of Herschel imaging, and a rich data set on local galaxies, we find an empirical variation in the relationship between the rest-frame UV slope (β) and the ratio of infrared-to-ultraviolet emission (L {sub IR}/L {sub UV} ≡ IRX) as a function of infrared luminosity, or total SFR. Both locally and at high-z, galaxies above SFR ≳ 50 M {sub ☉} yr{sup –1} deviate from the nominal IRX-β relation toward bluer colors by a factor proportional to their increasing IR luminosity. We also estimate contamination rates of DSFGs on high-z dropout searches of <<1% at z ≲ 4-10, providing independent verification that contamination from very dusty foreground galaxies is low in Lyman-break galaxy searches. Overall, our results are consistent with the physical interpretation that DSFGs, e.g., galaxies with >50 M {sub ☉} yr{sup –1}, are dominated at all epochs by short-lived, extreme burst events, producing many young O and B stars that are primarily, yet not entirely, enshrouded in thick dust cocoons. The blue rest-frame UV slopes of DSFGs are inconsistent with the suggestion that most DSFGs at z ∼ 2 exhibit steady-state star formation in secular disks.

  8. Determination of mass attenuation coefficients for threshold contrast evaluation in digital mammography (United States)

    Hummel, Johann; Semturs, Friedrich; Menhart, Susanne; Figl, Michael


    According to the 'European protocol for the quality control of the physical and technical aspects of mammography screening' (EPQC) image quality digital mammography units has to be evaluated at different breast thicknesses. At the standard thickness of 50 mm polymethyl methacrylate (PMMA) image quality is determined by the analysis of CDMAM contrast detail phantom images where threshold contrasts are calculated for different gold disc diameters. To extend these results to other breast thicknesses contrast-to-noise ratios (CNR) and threshold contrast (TC) visibilities have to be calculated for all required thicknesses. To calculate the latter the mass attenuation coefficient (MAC) of gold has to be known for all possible beam qualities in the tube voltage range between 26 and 32 kV. In this paper we first determined the threshold contrast visibility using the CDMAM phantom with the same beam quality at different current-time products (mAs). We can derive from Rose theory that CNR • CT • α = const, where α is the diameter of the gold cylinder. From this the corresponding attenuation coefficients can be calculated. This procedure was repeated for four different beam qualities (Mo/Mo 27kV, Rh/Rh 29kV, Rh/Rh 31 kV, and W/Rh 29 kV)). Next, we measured the aluminium half value layer (HVL) of all x-ray spectra relevant for mammography. Using a first order Taylor expansion of MAC as a function of HVL, all other desired MAC can be calculated. The MAC as a function of the HVL was derived to MAChvl = -286.97 * hvl+186.03 with R2 = 0.997, where MAChvl indicates the MAC for all specific x-ray spectrum defined by its aluminium half value layer. Based on this function all necessary MACs needed for quality assurance (QA) were calculated. The results were in good agreement with the data found in the protocol.

  9. Numerical investigation of the hydro-mechanical contribution to seismic attenuation in damaged rocks (United States)

    Pollmann, Nele; Jänicke, Ralf; Renner, Jörg; Steeb, Holger


    The investigation of hydro-mechanical processes, in particular the modeling of seismic waves in fractured porous media, is essential for the physical interpretation of data obtained from seismic exploration. Here, we specifically investigate attenuation processes in fluid-saturated porous rock containing fracture networks to identify effective hydro-mechanical properties by numerical simulation. The main purpose of this work is the characterization of the overall hydro-mechanical properties by computational homogenization. We determine an effective Skempton coefficient by investigating the fluid pressure and the solid displacement of the skeleton saturated by compressible fluids. Fracture networks are stochastically generated to mimic geological in-situ situations. The fractures are approximated as ellipses with aspect ratios up to 1/100, i.e. they constitute thin and long hydraulic conduits with high permeabilities. Simulations are designed on the material scale with and without conservation of fluid mass in the control volume. Using computational homogenization approaches, we define an effective Skempton coefficient. A range of fracture networks with different characteristic properties is studied for different varieties of fractures. On the material scale we find strongly heterogeneous pressure propagation in the fracture network and the surrounding rock, respectively. The pressure diffusion is much faster in the fracture network than in the matrix, rendering the macroscopic hydro-mechanical behavior strongly time dependent. The effective Skempton coefficient converges to an ensemble-specific instantaneous value and to 1 for long-time studies. The ultimate objective of our study is to evaluate whether constraints on the structure of fracture networks can be deduced from observations of attenuation and its frequency dependence.

  10. Aerobic Exercise Attenuated Bleomycin-Induced Lung Fibrosis in Th2-Dominant Mice (United States)

    Oliveira-Junior, Manoel Carneiro; Assumpção-Neto, Erasmo; Brandão-Rangel, Maysa Alves Rodrigues; Damaceno-Rodrigues, Nilsa Regina; Garcia Caldini, Elia; Velosa, Ana Paula Pereira; Teodoro, Walcy Rosolia; Ligeiro de Oliveira, Ana Paula; Dolhnikoff, Marisa; Eickelberg, Oliver; Vieira, Rodolfo Paula


    Introduction The aim of this study was to investigate the effect of aerobic exercise (AE) in reducing bleomycin-induced fibrosis in mice of a Th2-dominant immune background (BALB/c). Methods BALB/c mice were distributed into: sedentary, control (CON), Exercise-only (EX), sedentary, bleomycin-treated (BLEO) and bleomycin-treated+exercised (BLEO+EX); (n = 8/group). Following treadmill adaptation, 15 days following a single, oro-tracheal administration of bleomycin (1.5U/kg), AE was performed 5 days/week, 60min/day for 4 weeks at moderate intensity (60% of maximum velocity reached during a physical test) and assessed for pulmonary inflammation and remodeling, and cytokine levels in bronchoalveolar lavage (BAL). Results At 45 days post injury, compared to BLEO, BLEO+EX demonstrated reduced collagen deposition in the airways (p<0.001) and also in the lung parenchyma (p<0.001). In BAL, a decreased number of total leukocytes (p<0.01), eosinophils (p<0.001), lymphocytes (p<0.01), macrophages (p<0.01), and neutrophils (p<0.01), as well as reduced pro-inflammatory cytokines (CXCL-1; p<0.01), (IL-1β; p<0.001), (IL-5; p<0.01), (IL-6; p<0.001), (IL-13; p<0.01) and pro-fibrotic growth factor IGF-1 (p<0.001) were observed. Anti-inflammatory cytokine IL-10 was increased (p<0.001). Conclusion AE attenuated bleomycin-induced collagen deposition, inflammation and cytokines accumulation in the lungs of mice with a predominately Th2-background suggesting that therapeutic AE (15–44 days post injury) attenuates the pro-inflammatory, Th2 immune response and fibrosis in the bleomycin model. PMID:27677175

  11. Integrated MEMS-based variable optical attenuator and 10Gb/s receiver (United States)

    Aberson, James; Cusin, Pierre; Fettig, H.; Hickey, Ryan; Wylde, James


    MEMS devices can be successfully commercialized in favour of competing technologies only if they offer an advantage to the customer in terms of lower cost or increased functionality. There are limited markets where MEMS can be manufactured cheaper than similar technologies due to large volumes: automotive, printing technology, wireless communications, etc. However, success in the marketplace can also be realized by adding significant value to a system at minimal cost or leverging MEMS technology when other solutions simply will not work. This paper describes a thermally actuated, MEMS based, variable optical attenuator that is co-packaged with existing opto-electronic devices to develop an integrated 10Gb/s SONET/SDH receiver. The configuration of the receiver opto-electronics and relatively low voltage availability (12V max) in optical systems bar the use of LCD, EO, and electro-chromic style attenuators. The device was designed and fabricated using a silicon-on-insulator (SOI) starting material. The design and performance of the device (displacement, power consumption, reliability, physical geometry) was defined by the receiver parameters geometry. This paper will describe how these design parameters (hence final device geometry) were determined in light of both the MEMS device fabrication process and the receiver performance. Reference will be made to the design tools used and the design flow which was a joint effort between the MEMS vendor and the end customer. The SOI technology offered a robust, manufacturable solution that gave the required performance in a cost-effective process. However, the singulation of the devices required the development of a new singulation technique that allowed large volumes of silicon to be removed during fabrication yet still offer high singulation yields.

  12. Chlorella intake attenuates reduced salivary SIgA secretion in kendo training camp participants

    Directory of Open Access Journals (Sweden)

    Otsuki Takeshi


    Full Text Available Abstract Background The green alga Chlorella contains high levels of proteins, vitamins, and minerals. We previously reported that a chlorella-derived multicomponent supplement increased the secretion rate of salivary secretory immunoglobulin A (SIgA in humans. Here, we investigated whether intake of this chlorella-derived supplement attenuated the reduced salivary SIgA secretion rate during a kendo training camp. Methods Ten female kendo athletes participated in inter-university 6-day spring and 4-day summer camps. They were randomized into two groups; one took placebo tablets during the spring camp and chlorella tablets during the summer camp, while the other took chlorella tablets during the spring camp and placebo tablets during the summer camp. Subjects took these tablets starting 4 weeks before the camp until post-camp saliva sampling. Salivary SIgA concentrations were measured by ELISA. Results All subjects participated in nearly all training programs, and body-mass changes and subjective physical well-being scores during the camps were comparable between the groups. However, salivary SIgA secretion rate changes were different between these groups. Salivary SIgA secretion rates decreased during the camp in the placebo group (before vs. second, middle, and final day of camp, and after the camp: 146 ± 89 vs. 87 ± 56, 70 ± 45, 94 ± 58, and 116 ± 71 μg/min, whereas no such decreases were observed in the chlorella group (121 ± 53 vs. 113 ± 68, 98 ± 69,115 ± 80, and 128 ± 59 μg/min. Conclusion Our results suggest that a use of a chlorella-derived dietary supplement attenuates reduced salivary SIgA secretion during a training camp for a competitive sport.

  13. Physics Survey Overview

    Energy Technology Data Exchange (ETDEWEB)



    An overview of a series of assignments of the branches of physics carried out by the Board on Physics and Astronomy of the National Research Council. It identifies further theories in physics and makes recommendations on preventive priorities. The Board on Physics and Astronomy (BPA) has conducted a new decadal survey of physics entitled ''Physics in a New Era''. The survey includes assessments of the main branches of physics as well as certain selected emerging areas. The various elements of the survey were prepared by separately-appointed National Research Council (NRC) committees. The BPA formed the Physics Survey Overview Committee (PSOVC) to complete the survey by preparing an overview of the field of physics to summarize and synthesize the results of the various assessments and to address cross-cutting issues that concern physics as a whole.

  14. Quantum physics for beginners

    CERN Document Server

    Ficek, Zbigniew


    The textbook introduces students to the main ideas of quantum physics and the basic mathematical methods and techniques used in the fields of advanced quantum physics, atomic physics, laser physics, nanotechnology, quantum chemistry, and theoretical mathematics. The textbook explains how microscopic objects (particles) behave in unusual ways, giving rise to what's called quantum effects. It contains a wide range of tutorial problems from simple confidence-builders to fairly challenging exercises that provide adequate understanding of the basic concepts of quantum physics.

  15. P-wave attenuation anisotropy in TI media and its application in fracture parameters inversion (United States)

    He, Yi-Yuan; Hu, Tian-Yue; He, Chuan; Tan, Yu-Yang


    The existence of aligned fractures in fluid-saturated rocks leads to obvious attenuation anisotropy and velocity anisotropy. Attenuation anisotropy analysis can be applied to estimate fracture density and scale, which provide important information for reservoir identification. This paper derives P-wave attenuation anisotropy in the ATI media where the symmetry axis is in the arbitrary direction theoretically and modifies the spectral ratio method to measure attenuation anisotropy in the ATI media, thus avoiding a large measurement error when applied to wide azimuth or full azimuth data. Fracture dip and azimuth can be estimated through attenuation anisotropy analysis. For small-scale fractures, fracture scale and fracture density can be determined with enhanced convergence if velocity and attenuation information are both used. We also apply the modified spectralratio method to microseismic field data from an oilfield in East China and extract the fracture dip through attenuation anisotropy analysis. The result agrees with the microseismic monitoring.

  16. Applications of Hubble Volume in Atomic Physics, Nuclear Physics, Particle Physics, Quantum Physics and Cosmic Physics

    Directory of Open Access Journals (Sweden)

    U. V. S. Seshavatharam


    Full Text Available In this paper an attempt is made to emphasize the major shortcomings of standard cosmology. It can be suggested that, the current cosmological changes can be understood by studying the atom and the atomic nucleus through ground based experiments. If light is coming from the atoms of the gigantic galaxy, then redshift can be interpreted as an index of the galactic atomic ‘light emission mechanism’. In no way it seems to be connected with ‘galaxy receding’. With ‘cosmological increasing (emitted photon energy’, observed cosmic redshift can be considered as a measure of the age difference between our galaxy and any observed galaxy. If it is possible to show that, (from the observer older galaxy’s distance increases with its ‘age’, then ‘galaxy receding’ and ‘accelerating universe’ concepts can be put for a revision at fundamental level. At any given cosmic time, the product of ‘critical density’ and ‘Hubble volume’ gives a characteristic cosmic mass and it can be called as the ‘Hubble mass’. Interesting thing is that, Schwarzschild radius of the ‘Hubble mass’ again matches with the ‘Hubble length’. Most of the cosmologists believe that this is merely a coincidence. At any given cosmic time,’Hubble length’ can be considered as the gravitational or electromagnetic interaction range. If one is willing to think in this direction, by increasing the number of applications of Hubble mass and Hubble volume in other areas of fundamental physics like quantum physics, nuclear physics, atomic physics and particle physics - slowly and gradually - in a progressive way, concepts of ‘Black hole Cosmology’ can be strengthened and can also be confirmed.

  17. Videos of physics experiments. A supplementary educational tool for students and teachers

    CERN Document Server

    Pilakouta, M; Fragkedakis, E; Varsamis, C P


    The educational use of video and multimedia is increasing rapidly in secondary and higher education across all disciplines. Videos for physics education can be found in many universities and other educational institutions websites all over the world. In the area of experimental physics, the available videos demonstrate mainly physical phenomena or physics experiments and only few of them allow for the quantitative estimation of physical parameters. In this work, we present characteristic videos of an ongoing project aiming at the development of a collection of educational videos that guide students to measure data and to analyze them in order to calculate physical quantities. These videos can be used for physics teaching, as a demonstration, as a supplementary educational tool for the students pre lab preparation and also in the physics lab, if the necessary equipment is not available or in case of time consuming measurements. The pilot use of a video related to the measurement of the lead attenuation coeffic...

  18. Implementation of Physical Layer Key Distribution using Software Defined Radios

    Directory of Open Access Journals (Sweden)

    S. Kambala


    Full Text Available It was well known from Shannon’s days that characteristics of the physical channel like attenuation, fading and noise can impair reliable communication. But it was more recently that the beneficial side effects of channel characteristics in ensuring secret communication started getting attention. Studies have been made to quantify the amount of secrecy that can be reaped by combining channel coding with security protocols. The Wiretap channel proposed by Wyner is arguably one of the oldest models of physical layer security protocols. In this paper, we present a brief tutorial introduction to the Wiretap channel, followed by an application of the physical layer model to a class of Key Distribution protocols. We present results from an implementation of key distribution protocols using Software Defined Radio tools along with physical RF hardware peripherals. We believe this approach is much more tangible and informative than computer based simulation studies.

  19. Predisposing, Reinforcing and Enabling Predictors of Middle School Children's After-School Physical Activity Participation (United States)

    King, Kristi M.; Ogletree, Roberta J.; Fetro, Joyce V.; Brown, Stephen L.; Partridge, Julie A.


    Children's participation in after-school physical activity can attenuate the overweight and obesity rates among rural, low socioeconomic status (SES) children. Children's individual determination, as well as social and environmental factors, can influence their behaviors. Purpose: The purposes of this study were to determine if a difference…

  20. Teaching Physics: with the Physics Suite (United States)

    Redish, Edward F.


    Acompanion guide to using the Physics Suite,Teaching Physicsis a book about learning to be a more effective physics teacher. It is meant for anyone who is interested inlearning about recent developments in physics education. It is not a review of specific topics in physics with hints for how to teach them and lists of common student difficulties. Rather, it is a handbook with a variety of tools for improving both teaching and learning of physics from new kinds of homework and exam problems, to surveys for figuring out what has happened in your class, to tools for taking and analyzing data using computers and video. Teaching Physics includes: an introduction to the cognitive model of thinking and learning that underlies modern physics education research principles and guidelines for making use of and understanding the implications of this cognitive model for the classroom a discussion of formative and summative evaluation with a variety of "thinking problems" useful for homework and exams a discussion of assessment of the success of instruction using research-based concept and attitude surveys discussion of 11 research-based curricular materials for use in lecture, lab, recitation, and workshops environments tips and guidelines for how to improve your instruction In addition, the book comes with a Resource CD containing 14 conceptual and 3 attitude surveys, more than 250 thinking problems covering all areas of introductory physics, resource materials from commercial vendors on use of computerized data acquisition and video, and a variety of other useful reference materials.