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Sample records for attention deficit hyperactivity disorder

  1. Attention deficit hyperactivity disorder

    OpenAIRE

    Doğangün, Burak; Yavuz, Mesut

    2011-01-01

    Attention deficit hyperactivity disorder is characterized by excessive overactiviy inattention and impulsiveness It is reported that attention deficit hyperactivity disorder affects 5 12 of children worldwide It has significant negative effects on psychological and social development and academic functioning of the children if it remains nbsp; untreated The etiology of attention deficit hyperactivity disorder is unknown Genetic neurodevelopmental neurophysiological and psychosocial factors ar...

  2. Attention deficit hyperactivity disorder

    OpenAIRE

    2001-01-01

    Over the last two decades, there have been numerous technical and methodological advances available to clinicians and researchers to better understand attention deficit hyperactivity disorder (ADHD) and its etiology. Despite the growing body of literature investigating the disorder’s pathophysiology, ADHD remains a complex psychiatric disorder to characterize. This chapter will briefly review the literature on ADHD, with a focus on its history, the current genetic insights, neurophysiologic t...

  3. Attention deficit hyperactivity disorder.

    Science.gov (United States)

    Thapar, Anita; Cooper, Miriam

    2016-03-19

    Attention deficit hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder with a prevalence of 1·4-3·0%. It is more common in boys than girls. Comorbidity with childhood-onset neurodevelopmental disorders and psychiatric disorders is substantial. ADHD is highly heritable and multifactorial; multiple genes and non-inherited factors contribute to the disorder. Prenatal and perinatal factors have been implicated as risks, but definite causes remain unknown. Most guidelines recommend a stepwise approach to treatment, beginning with non-drug interventions and then moving to pharmacological treatment in those most severely affected. Randomised controlled trials show short-term benefits of stimulant medication and atomoxetine. Meta-analyses of blinded trials of non-drug treatments have not yet proven the efficacy of such interventions. Longitudinal studies of ADHD show heightened risk of multiple mental health and social difficulties as well as premature mortality in adult life. PMID:26386541

  4. Attention Deficit Hyperactivity Disorder (ADHD)

    Centers for Disease Control (CDC) Podcasts

    2014-04-10

    This podcast discusses Attention Deficit Hyperactivity Disorder, or ADHD, the most common behavioral disorder in children. Learn about symptoms, risk factors, and treatment.  Created: 4/10/2014 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 5/7/2014.

  5. Focusing on ADHD - Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    ... review our exit disclaimer . Subscribe Focusing on ADHD Attention Deficit Hyperactivity Disorder Most children get restless, rowdy, or distracted at ... might be signs of a developmental disorder called attention deficit hyperactivity disorder, or ADHD. ADHD is a common brain condition ...

  6. Attention-deficit hyperactivity disorder.

    Science.gov (United States)

    Wolraich, Mark L

    2006-12-01

    Attention-deficit hyperactivity disorder (ADHD) is a challenging condition to diagnose and treat. For diagnosis, the clinician needs to establish the presence of ADHD on Diagnostic and Statistical Manual of Mental Disorders criteria requiring information from parents and teachers and considering both alternative diagnoses and co-occurring conditions. In the treatment of ADHD as a chronic illness, the clinician needs to educate the family about the condition and partner with them about treatment decisions. The 2 treatments with demonstrated efficacy for ADHD are medications (stimulant medications and a selective norepinephrine reuptake inhibiter) and behavior-modification programs. PMID:17178358

  7. Faststats: Attention Deficit Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    ... this? Submit What's this? Submit Button NCHS Home Attention Deficit Hyperactivity Disorder (ADHD)* Recommend on Facebook Tweet ... physician offices, hospital outpatient and emergency departments) with attention deficit disorder as primary diagnosis: 9.0 million ( ...

  8. Attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Shaywitz, B A; Fletcher, J M; Shaywitz, S E

    1997-01-01

    In this chapter we have reviewed the diagnosis and management of attention deficit disorder, focusing particularly on the role of stimulant therapy in ADHD. Hisorical review suggests that ADHD has roots that extend back almost a century. The definition of ADHD is based on inclusion and exclusion criteria that are established by history and reflect behavioral concerns. Attention-deficit/hyperactivity disorder is a chronic disorder affecting the child's home, school, and community life. The primary symptoms of the disorder manifest a developmental pattern: activity diminishes while attentional deficits persist. Major sources of concern are the secondary and often more resistant problems of learning difficulties, behavioral problems, lack of peer acceptance, and low self-esteem. An often frustrating and perplexing characteristic of the disorder is its marked variability-over time, across situations, and within the same child and similar situations. Educational management represents an important priority and often forms the cornerstone of all other therapies, nonpharmacologic or pharmacologic. Cognitive-behavioral therapies represent the most widely used alternative to pharmacotherapy. Although the effects of CBT alone are disappointing, recent studies suggest that such therapies may provide a useful adjunct to pharmacotherapy and may be helpful when children are tapered off medication. Psychotherapy, or a combination of psychotherapy and medication (termed multimodality therapy), may also be useful. Pharmacotherapy for ADHD originated almost 60 years ago, and at this time the ameliorative effects of medications in ADHD are well established. The general skepticism of experienced clinicians, coupled with a climate where parents are reluctant to medicare children, serves to limit their use except where indicated. Although the effects of stimulants on attention and activity seem well established, effects on cognition, conduct, and social behavior are more controversial

  9. Medication Treatment for Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Ryan, Joseph B.; Katsiyannis, Antonis; Hughes, Elizabeth M.

    2011-01-01

    Attention deficit hyperactivity disorder (ADHD) has become the most commonly diagnosed psychiatric disorder among school-age children. For more than half a century, physicians have prescribed medications to help manage behaviors such as hyperactivity, impulsivity, and inattention. Today, there is a growing consensus that ADHD is a biologically…

  10. Genetic Basis of Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Nihal Yurteri; A. Evren Tufan; Gizem Melissa Akgun; Ayten Erdogan

    2011-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neuropsychiatric disorders of childhood. Due to studies reporting that the effects of ADHD diagnosis on functioning may last throughout life, this disorder, which has great importance for child and adolescent psychiatry, started to attract greater attention recently in terms of adult psychiatry. A review, evaluating the results of studies conducted on the genetic basis of ADHD, which started to attract increasing attent...

  11. Mindfulness and Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Smalley, Susan L; Loo, Sandra K.; Hale, T. Sigi; Shrestha, Anshu; Mcgough, James,; Flook, Lisa; Reise, Steven

    2009-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) is a disorder characterized by attentional difficulties. Mindfulness is a receptive attention to present experience. Both ADHD and mindfulness are associated with attention and personality. This study tests whether individuals with ADHD have lower mindfulness scores than controls and, if true, whether personality contributes to these differences. 105 adults (half with ADHD) were assessed for mindfulness, using the Kentucky Inventory of Mindfulne...

  12. Stigma in attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Müller, Kathi; Fuermaier, Anselm B M; Koerts, Janneke; Tucha, Lara

    2012-01-01

    Attention deficit hyperactivity disorder (ADHD) is a frequently diagnosed disorder in child- and adulthood with a high impact affecting multiple facets of social life. Therefore, patients suffering from ADHD are at high risk to be confronted with stigma, prejudices, and discrimination. A review of t

  13. Medical Comorbidities in Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Irem Yalug

    2009-09-01

    Full Text Available Attention Deficit Hyperactivity Disorder is one of the most common developmental disorders of childhood with a reported world-wide prevalence of 8 to 12 %. In studies conducted in our country the prevalence rates in community were reported to vary between 8.6 to 8.1 % while clinical prevalence rates were reported to vary between 8.6 to 29.44 %. Fifty to eighty percent of cases were reported to continue into adolescence while thirty to fifty percent may continue into adulthood. Attention deficit hyperactivity disorder is known to accompany subtle physical anomalies, allergic and neurologic disorders, obesity and eating disorders, traumatic injuries, risky sexual behavior, sleep disorders, substance and alcohol use, axis I and II disorders, occupational, legal and academic problems and increased treatment expenditures. Though the effects of this disorder continue throughout life, create burdens to the society along with its treatment as well as disabling the affected patients through their lives, and receive increasing attention in recent years, reviews focusing on problems associated with it are lacking. Therefore, this study aimed to summarize the results of previous studies conducted about medical comorbidities in attention deficit hyperactivity disorder.

  14. Attention deficit hyperactivity disorder in prison inmates

    OpenAIRE

    Ginsberg, Ylva

    2012-01-01

    Background: Attention deficit hyperactivity disorder (ADHD) is an inherited developmental disorder with early onset, chronically persisting in the vast majority of cases. ADHD is associated with pervasive cognitive, emotional and functional impairments, as well as an increased rate of coexisting disorders. ADHD in the presence of early disruptive behaviours increase the risk for later delinquency. ADHD is estimated to be present in about 25-45% of adult prison inmates, thus 10-times increased...

  15. Functional MRI and Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-12-01

    Full Text Available The Stroop effect, a measure for selective attention, on behavioral and brain activation of attention deficit hyperactivity disorder (ADHD children (9 boys, ages 9.8-14.5 years, off or on methylphenidate and 9 controls was studied using event-related functional magnetic resonance imaging (fMRI at the Institute of Mental Health, Peking University, Beijing, China, and other centers in China and at Harvard Medical School, Boston, MA, USA.

  16. What causes attention deficit hyperactivity disorder?

    OpenAIRE

    Thapar, Anita; Cooper, Miriam; Jefferies, Rachel; Stergiakouli, Evangelia

    2011-01-01

    Attention deficit hyperactivity disorder (ADHD) affects around 1–3% of children. There is a high level of comorbidity with developmental and learning problems as well as with a variety of psychiatric disorders. ADHD is highly heritable, although there is no single causal risk factor and non-inherited factors also contribute to its aetiology. The genetic and environmental risk factors that have been implicated appear to be associated with a range of neurodevelopmental and neuropsychiatric outc...

  17. Stigma in attention deficit hyperactivity disorder

    OpenAIRE

    Mueller, Anna K; Anselm B M Fuermaier; Koerts, Janneke; Tucha, Lara

    2012-01-01

    Attention deficit hyperactivity disorder (ADHD) is a frequently diagnosed disorder in child- and adulthood with a high impact affecting multiple facets of social life. Therefore, patients suffering from ADHD are at high risk to be confronted with stigma, prejudices, and discrimination. A review of the empirical research in the field of ADHD with regard to stigma was performed. The findings of investigations in this field were clustered in different categories, including stigma in children wit...

  18. Attention Deficit/Hyperactivity Disorder: Pharmacotherapy

    OpenAIRE

    Elia, Josephine

    2005-01-01

    Pharmacotherapy, one of the effective modalities of treatment for attention deficit/hyperactivity disorder (ADHD), was discovered serendipitously and, until recently, consisted primarily of short-acting methylphenidate and dextroamphetamine compounds. The US Food and Drug Administration's (FDA) approval of Concerta in 2000 followed by approval of additional long-acting methylphenidate (Ritalin LA; Metadate CD) and amphetamine formulations (Adderall XR) expanded the repertoire. By providing su...

  19. Attention Deficit Hyperactivity Disorder in Epileptic Children

    OpenAIRE

    Kim, Gun-Ha; Kim, Ji Yeon; Byeon, Jung Hye; Eun, Baik-Lin; Rhie, Young Jun; Seo, Won Hee; Eun, So-Hee

    2012-01-01

    It is well-known that the prevalence of attention deficit hyperactivity disorder (ADHD) is higher in epileptic children than in the general pediatric population. The aim of this study was to compare the accompaniment of ADHD in epileptic children with well-controlled seizures and no significant intellectual disability with that in healthy controls. We included epileptic children between the ages of 6 and 12 yr visiting our clinic for six consecutive months and controls without significant med...

  20. Treatment Approaches to Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Antai-Otong, Deborah; Zimmerman, Michele L

    2016-06-01

    Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, adolescents, and adults, with a prevalence estimated from 5% to 7% across cultures and approximately 2% to 5% in adults. This lifelong disorder challenges nurses to understand the basis of ADHD, analyze symptoms, differentiate coexisting disorders, gather health information from varied sources, and implement person-centered multimodal treatment. Nurses are poised to plan, and work with patients, families, and teachers in the community and school systems to optimize academic and occupational performance and improve quality of life. Pharmacotherapy, psychoeducation, and behavioral therapies are strong components of multimodal treatment planning. PMID:27229276

  1. Medical Comorbidities in Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Irem Yalug; Ali Evren Tufan

    2009-01-01

    Attention Deficit Hyperactivity Disorder is one of the most common developmental disorders of childhood with a reported world-wide prevalence of 8 to 12 %. In studies conducted in our country the prevalence rates in community were reported to vary between 8.6 to 8.1 % while clinical prevalence rates were reported to vary between 8.6 to 29.44 %. Fifty to eighty percent of cases were reported to continue into adolescence while thirty to fifty percent may continue into adulthood. Attention defic...

  2. Management of attention-deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Rohit Verma

    2011-01-01

    Full Text Available Attention-deficit hyperactivity disorder (ADHD/ADD is a neurobehavioral disorder of childhood onset characterized by severe, developmentally inappropriate motor hyperactivity, inattention, and impulsiveness that result in impairment in more than one setting. It affects the home, school, and community life of 39% of school-going children worldwide. There is increasing recognition that ADHD symptoms and clinically defined disorder can persist into adult life and are associated with later drug and alcohol misuse and social and work difficulties. Added to that is the extreme variability of the disorder over time, within the same individual, between individuals, and across different circumstances. Treatment with stimulants and nonstimulants has proven effective in different subgroups, with the effectiveness of specific agents most likely related to the primary neurotransmitter involved. However, stimulants with a short duration of action have been problematic for some patients. Parent training and cognitive behavioral therapies represent the most widely adjunct psychosocial interventions to pharmacotherapy.

  3. Inattentiveness in attention-deficit/hyperactivity disorder

    Institute of Scientific and Technical Information of China (English)

    Ariane Sroubek; Mary Kelly; Xiaobo Li

    2013-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with a long-term impact on functioning,productivity and quality of life of patients.This impact is largely due to the symptoms of inattentiveness.However,despite its impairing role in the lives of ADHD patients,inattentiveness has been studied relatively less frequently than have symptoms of impulsivity/hyperactivity and problems with executive function.This review therefore seeks to integrate the neuropsychological theories and current findings in the research fields of neuropsychology,neurophysiology,and neuroimaging,in an attempt to gain a more complete understanding of the role that inattentiveness plays in ADHD,as well as to suggest directions for future studies.The need for a more comprehensive understanding of inattentiveness and ADHD,which integrates findings from each of the three disciplines mentioned above,is emphasized.

  4. Genetic Basis of Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Nihal Yurteri

    2011-01-01

    Full Text Available Attention Deficit Hyperactivity Disorder (ADHD is one of the most common neuropsychiatric disorders of childhood. Due to studies reporting that the effects of ADHD diagnosis on functioning may last throughout life, this disorder, which has great importance for child and adolescent psychiatry, started to attract greater attention recently in terms of adult psychiatry. A review, evaluating the results of studies conducted on the genetic basis of ADHD, which started to attract increasing attention both in our country and the world, was thought to help clinicians working in this field. PubMed and Turkish Psychiatry Index online search engines were screened using “attention deficit hyperactivity disorder”, “ADHD”, “genetics” as key words. The data obtained were combined with information gleaned from several textbooks. Based on previous studies, it could easily be concluded that ADHD is one of the most common heritable psychiatric disorder with distinguished genetic features. Despite its importance for diagnosis and treatment, the etiology of ADHD is still not clear and the disorder seems to be a complex problem arising from the effects of both genetic and environmental factors. Although previous studies revealed that ADHD displayed familial and hereditary transmission, stable patterns of Mendelian inheritance could not be discriminated by evaluation of pedigrees. Therefore, many studies have been conducted on the molecular genetic basis of ADHD recently. The previous studies did not report consistent results in identification of the genes responsible for ADHD which has been partially linked to heterogeneity of the disorder. Grouping relevant patients according to comorbidities and persistence in adolescence rather than DSM-IV subtypes could be an important alternative method for overcoming this limitation in the research studies.

  5. Connectivity supporting attention in children with attention deficit hyperactivity disorder

    OpenAIRE

    Barber, Anita D.; Jacobson, Lisa A.; Joanna L. Wexler; Mary Beth Nebel; Caffo, Brian S.; Pekar, James J.; Mostofsky, Stewart H.

    2014-01-01

    Intra-subject variability (ISV) is the most consistent behavioral deficit in Attention Deficit Hyperactivity Disorder (ADHD). ISV may be associated with networks involved in sustaining task control (cingulo-opercular network: CON) and self-reflective lapses of attention (default mode network: DMN). The current study examined whether connectivity supporting attentional control is atypical in children with ADHD. Group differences in full-brain connection strength and brain–behavior associations...

  6. Detection of feigned attention deficit hyperactivity disorder.

    Science.gov (United States)

    Tucha, Lara; Fuermaier, Anselm B M; Koerts, Janneke; Groen, Yvonne; Thome, Johannes

    2015-08-01

    In recent years, there is an increasing awareness that individuals may purposely feign or exaggerate symptoms of attention deficit hyperactivity disorder (ADHD) to gain external incentives, including access to stimulant drugs or special academic accommodations. There are vast consequences of undetected feigned ADHD such as substantial costs covered by society for unnecessary assessments and treatments, unjustified occupation of limited medical resources and undermining society's trust in the existence of the disorder or the effectiveness of treatment. In times of economic crisis and cost savings in the medical sector, the detection of feigned ADHD is of importance. This review briefly describes the research on this topic with an emphasis on the approaches available for detection of feigned ADHD (i.e., self-report questionnaires, personality inventories, cognitive tests used in routine neuropsychological assessment and tests specifically designed for detecting feigned cognitive dysfunction). Promising approaches and measures are available for identifying feigned ADHD but there is an immediate need for further research. PMID:25096370

  7. ATTENTION DEFICIT HYPERACTIVITY DISORDER. A CLINICAL LECTURE

    Directory of Open Access Journals (Sweden)

    A. S. Kotov

    2015-01-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is a serious problem to pediatric neurologists. The prevalence of ADHD in developed countries ranges from 1 to 20 %. ADHD is characterized by a triad of symptoms: inattention, hyperactivity, and impulsivity (the International Statistical Classification of Diseases, 10th revision, codes it as F90 and it is the most common conduct disorder in children. The etiology of ADHD remains disсutable to the present day; there are a few basic concepts of the origin of this disorder. Its manifestations may be a reason for family conflicts, poor peer relationships, social and school maladjustment, learning problems, lower academic performance, accidents and injuries, smoking, psychoactive substance abuse (toxicomania, narcomania, delinquencies, deviant social behavior, thus having a negative impact on all spheres of a patient’s life. The manifestations of ADHD may continue in adulthood, resulting in work and family life problems, low self-evaluation, alcohol and psychoactive substance abuse, and other unfavorable consequences. The authors describe the etiology, pathogenesis, diagnostic principles (diagnostic scales and tests, differential diagnosis (by setting out a large group of different diseases, the manifestations of which can mimic ADHD, treatment, and prognosis of the disorder. Within its therapeutic correction framework, the authors present the definition and general principles of Montessori therapy, including recommendations for parents and relatives to deal with children with ADHD. 

  8. Dansk standardisering af attention deficit/hyperactivity disorder-ratingskalaen

    DEFF Research Database (Denmark)

    Poulsen, Lotte; Jørgensen, Siv Lykke; Dalsgaard, Søren;

    2009-01-01

    INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) is characterized by inattention, hyperactivity and impulsivity. The diagnostic classification is based on developmental anamnesis, objective examination, neuropsychological tests, observation of the child, and evaluation of the symptoms...

  9. Attention-deficit/hyperactivity disorder (ADHD)

    DEFF Research Database (Denmark)

    Dalsgaard, S.

    2013-01-01

    The proposed revision of the diagnostic criteria in DSM-5 for attention-deficit/hyperactivity disorder (ADHD) will not fundamentally change the concept of ADHD. This is mainly due to the fact that, DSM-5 will retain the exact DSM-IV wording of all 18 symptoms, but will add new examples that make...... changes will most likely increase the prevalence of ADHD, especially in adults and adolescents, but maybe also in children. The added examples will also result in necessary revisions and new validations of rating scales and diagnostic interviews. This review will examine each of the proposed DSM-5 changes...... and the impact they may have, and in addition, the paper will make an overview of the main characteristics of some of the international and national guidelines for assessment and treatment of ADHD and how these impact the clinical practice....

  10. Current pharmacotherapy of attention deficit hyperactivity disorder.

    Science.gov (United States)

    Reddy, D S

    2013-10-01

    Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder in children and adults characterized by a persistent pattern of impulsiveness, inattention and hyperactivity. It affects about 3-10% of children and 2-5% of adolescents and adults and occurs about four times more commonly in boys than girls. The cause of ADHD is unknown, but it has strong genetic and environment components. The first-line treatment options for ADHD include behavioral therapy, pharmacotherapy with stimulants or both. Methylphenidate and amphetamine salts are the stimulant drugs of choice for ADHD treatment. Amphetamines act by increasing presynaptic release of dopamine and other biogenic amines in the brain. Methylphenidate inhibits the reuptake of dopamine and norepinephrine and therefore its pharmacology is identical to that of amphetamines. Lisdex-amfetamine is a prodrug of dextroamphetamine with low feasibility for abuse. Atomoxetine, a selective norepinephrine reuptake inhibitor, is an alternative, non-stimulant drug for ADHD but it is less efficacious than stimulants. Stimulants are generally safe but are associated with adverse effects including headache, insomnia, anorexia and weight loss. There is increased awareness about serious cardiovascular and psychiatric adverse events with ADHD drugs including concern for growth suppression in children. Stimulants have a high potential for abuse and dependence, and should be handled safely to prevent misuse and abuse. PMID:24191257

  11. Does mindfulness meditation improve attention in attention deficit hyperactivity disorder?

    Science.gov (United States)

    Modesto-Lowe, Vania; Farahmand, Pantea; Chaplin, Margaret; Sarro, Lauren

    2015-12-22

    Attention deficit hyperactivity disorder (ADHD) manifests by high levels of inattention, impulsiveness and hyperactivity. ADHD starts in childhood and results in impairments that continue into adulthood. While hyperactivity declines over time, inattention and executive function difficulties persist, leading to functional deficits. Adolescents and adults with ADHD have pervasive impairment in interpersonal and family relationships. They may develop addiction, delinquent behavior and comorbid psychiatric disorders. Despite advances in diagnosis and treatment, persistent residual symptoms are common, highlighting the need for novel treatment strategies. Mindfulness training, derived from Eastern meditation practices, may improve self-regulation of attention. It may also be a useful strategy to augment standard ADHD treatments and may be used as a potential tool to reduce impairments in patients with residual symptoms of ADHD. Clinically, this would manifest by an increased ability to suppress task-unrelated thoughts and distractions resulting in improved attention, completion of tasks and potential improvement in occupational and social function. PMID:26740931

  12. Attentional blink in children with attention deficit hyperactivity disorder

    OpenAIRE

    Juan A. Amador-Campos; J. Antonio Aznar-Casanova; Izabela Bezerra; Nelson Torro-Alves; Manuel M. Sánchez

    2015-01-01

    Objective:To explore the temporal mechanism of attention in children with attention deficit hyperactivity disorder (ADHD) and controls using a rapid serial visual presentation (RSVP) task in which two letters (T1 and T2) were presented in close temporal proximity among distractors (attentional blink [AB]).Method:Thirty children aged between 9 and 13 years (12 with ADHD combined type and 18 controls) took part in the study. Both groups performed two kinds of RSVP task. In the single task, part...

  13. The Source for ADD/ADHD: Attention Deficit Disorder and Attention Deficit/Hyperactivity Disorder.

    Science.gov (United States)

    Richard, Gail J.; Russell, Joy L.

    This book is intended for professionals who are responsible for designing and implementing educational programs for children with attention deficit disorders and attention deficit/hyperactivity disorder (ADD/ADHD). Chapters address: (1) myths and realities about ADD/ADHD; (2) definitions, disorders associated with ADD/ADHD, and federal educational…

  14. Developmental psychopathology: Attention Deficit Hyperactivity Disorder (ADHD

    Directory of Open Access Journals (Sweden)

    Petermann Franz

    2009-09-01

    Full Text Available Abstract Background Attention Deficit/Hyperactivity Disorder (ADHD, formerly regarded as a typical childhood disorder, is now known as a developmental disorder persisting over the lifespan. Starting in preschool-age, symptoms vary depending on the age group affected. Method According to the variability of ADHD-symptoms and the heterogeneity of comorbid psychiatric disorders, a broad review of recent studies was performed. These findings were summarized in a developmental psychopathological model, documenting relevant facts on a timeline. Results Based on a genetic disposition and a neuropsychological deregulation, there is evidence for factors which persist across the lifespan, change age-dependently, or show validity in a specific developmental phase. Qualitative changes can be found for children in preschool-age and adults. Conclusion These differences have implications for clinical practice as they can be used for prevention, diagnostic proceedings, and therapeutic intervention as well as for planning future studies. The present article is a translated and modified version of the German article "Entwicklungspsychopathologie der ADHS", published in Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 56, 2008, S. 265-274.

  15. Collicular dysfunction in attention deficit hyperactivity disorder.

    Science.gov (United States)

    Overton, Paul G

    2008-01-01

    Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterised by (inter alia) an increase in distractibility. The current front-line pharmacotherapies for the treatment of ADHD, namely the psychostimulants methylphenidate and amphetamines, have clear abuse potential, hence there is a strong need to develop new drug treatments for this disorder. Central to this process is the identification of the pathophysiological changes which underlie ADHD. Given the heterogeneity of the disorder, multiple loci are probably involved, providing multiple potential therapeutic targets. Here, we hypothesise (Hypothesis 1) that one such locus is the superior colliculus (SC), a sensory structure intimately linked with distractibility and the production of eye and head movements. It is proposed that in ADHD, the colliculus is hyper-responsive, leading to the core symptom of increased distractibility. Hypothesis 1 is supported by: 1. ADHD patients show increased distractibility in tasks which are sensitive to collicular function; 2. ADHD patients have a general problem inhibiting saccades, the generation of which involves the SC; 3. Saccadic deficits in ADHD include defects in the production of saccadic types (anti-saccades and express saccades) which are particularly associated with the colliculus; 4. Covert shifts in attention (which also have been argued to involve the SC) are also impaired in ADHD; 5. Reading disorders are frequently co-morbid with ADHD; dyslexia (which is associated with eye movement problems) is linked to a specific visual perceptual deficit in the M pathway, a major recipient of which is the colliculus. Whether or not the SC is indeed hyper-responsive in ADHD as Hypothesis 1 suggests, the SC may well represent an important therapeutic target for drugs. In fact current psychostimulant therapies, which reduce distractibility, may already work at that level (Hypothesis 2), a contention which is supported by: 1. The

  16. Attention-deficit disorder (attention-deficit/hyperactivity disorder without hyperactivity): A neurobiologically and behaviorally distinct disorder from attention-deficit/hyperactivity disorder (with hyperactivity)

    OpenAIRE

    Diamond, Adele

    2005-01-01

    Most studies of attention-deficit/hyperactivity disorder (ADHD) have focused on the combined type and emphasized a core problem in response inhibition. It is proposed here that the core problem in the truly inattentive type of ADHD (not simply the subthreshold combined type) is in working memory. It is further proposed that laboratory measures, such as complex-span and dual-task dichotic listening tasks, can detect this. Children with the truly inattentive type of ADHD, rather than being dist...

  17. Attention-deficit hyperactivity disorder in bipolar disorder

    OpenAIRE

    Rydén, Eleonore

    2010-01-01

    Attention-deficit hyperactivity disorder (ADHD) is a developmental disorder, i.e., it is by definition present from childhood. The main features characterizing ADHD are the difficulties to regulate attention, activity level, and impulses. The hallmark of bipolar disorder is episodic mood alterations with restitution between episodes. Although debut in childhood may occur, bipolar disorder typically debuts in late adolescence or early adulthood. The overarching aim with this ...

  18. Differentiating Attention Deficits in Children with Fetal Alcohol Spectrum Disorder or Attention-Deficit-Hyperactivity Disorder

    Science.gov (United States)

    Kooistra, Libbe; Crawford, Susan; Gibbard, Ben; Ramage, Barbara; Kaplan, Bonnie J

    2010-01-01

    Aim: The attention and inhibition problems found in children with attention-deficit-hyperactivity disorder (ADHD) are also common in children with fetal alcohol spectrum disorders (FASDs). Attempts to distinguish ADHD from FASDs in terms of these deficits are rare and were pursued in this study. Method: A total of 116 children (47 with ADHD, 31…

  19. Attention Deficit Hyperactivity Disorder and Scientific Epistemology

    Directory of Open Access Journals (Sweden)

    Steven Thurber

    2009-12-01

    Full Text Available Attention Deficit Hyperactivity Disorder (ADHD continues to be controversial with arguments for and against its veracity being waged by individuals representing a variety of disciplines from behavioral scientists to philosophers. Our perspective focuses on the epistemological underpinnings of what is now commonly known as ADHD. Its ignominious history and current disputes may stem from a "pessimistic" epistemology, meaning that truth is only the province of persons in authority and power. The authoritative organizations that govern the diagnostic labels and criteria are the American Psychiatric Association and their Diagnostic and Statistical Manual and the World Health Organization that sponsors the International Classification of Disease. We contrast the pessimistic epistemology with criteria for truth from the scientific method. Although scientific scrutiny has been and is being applied subsequent to "authoritarian edicts" of the disorder, we opine that ADHD currently does not have status beyond that of the "hypothetical construct." Moreover, current brain-based causal models have failed to provide rigorous supporting data that comes from testing falsifiable hypotheses.

  20. Use of stimulants for attention deficit hyperactivity disorder: FOR

    OpenAIRE

    Coghill, David

    2004-01-01

    Definitive diagnosis of attention deficit hyperactivity disorder is complex. David Coghill believes the condition is undertreated, but Harvey Markovitch argues that current uncertainties about diagnosis and treatment mean doctors should be cautious

  1. Use of stimulants for attention deficit hyperactivity disorder: AGAINST

    OpenAIRE

    Marcovitch, Harvey

    2004-01-01

    Definitive diagnosis of attention deficit hyperactivity disorder is complex. David Coghill believes the condition is undertreated, but Harvey Markovitch argues that current uncertainties about diagnosis and treatment mean doctors should be cautious

  2. Comorbidity of Social Anxiety Disorder and Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Ahmet Koyuncu

    2014-02-01

    Full Text Available Despite high rates of reported comorbidity in patients with social anxiety disorder, attention deficit hyperactivity disorder comorbidity was not evaluated in these studies. Studies, investigating the prevalence of adult attention deficit hyperactivity disorder (ADHD comorbidity in social anxiety disorder are limited and little is known about it. The reason for this may be the fact that, ADHD have been seen as a childhood disease over a period of time. In the prospective studies ,it is reported that ADHD is often observed in the adulthood and effects persist . On the other hand, studies on attention deficit hyperactivity disorder, higher rates of social anxiety disorder comorbidity have been reported. The presence of comorbid anxiety disorder increases the risk of impulsive feature in ADHD, causes problems in functionality, impaired compliance and resistance to the treatment. The aim of this article is to investigate the the status of social anxiety disorder and ADHD comorbidity and to discuss the hypothesis of antidepressant-associated hypomanic shift due to antidepressant treatment in social anxiety disorder patients. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2014; 6(1.000: 10-21

  3. Neurocognitive psychotherapy for adult attention deficit hyperactive disorder

    Directory of Open Access Journals (Sweden)

    Susmita Halder

    2009-01-01

    Full Text Available Previously thought as a childhood disorder, attention-deficit hyperactivity disorder (ADHD is reported to be spreading at an increasing rate and affecting 4% to 5% of the adult population. It is characterized by persistent problems of inattention, hyperactivity and impulsivity. We present the case of an adult ADHD patient intervened with neurocognitive psychotherapy.

  4. The Relationship between Attention Deficit Hyperactivity Disorder and Child Temperament

    Science.gov (United States)

    Foley, Marie; McClowry, Sandra Graham; Castellanos, Francisco X.

    2008-01-01

    This study examined empirical and theoretical differences and similarities between attention deficit hyperactivity disorder (ADHD) and child temperament in 32 ADHD children aged 6-11 years, and a comparison group of 23 children with similar sociodemographic characteristics. Children were assessed for ADHD symptoms (hyperactivity, impulsivity, and…

  5. Visual Spatial Attention in Children with Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Chung-Yao Chen

    2002-08-01

    Full Text Available Background: Attention deficit hyperactivity disorder (ADHD was characterized by deficitin the attention mechanism. Until now, the visual-spatial attention deficit inchildren with ADHD remains controversial. We report a study of the visualspatial attention to assess covert shifts of attention and sustained attentiontheoretically linked to two neuroanatomically defined attentional system inthe posterior and anterior parts of the human brain.Methods: Using the Neuroscan system, the reaction time (RT was measured accordingto three different within-subject conditions including cueing (valid, invalidand neutral; delay (800 msec and 100 msec; side [right visual field (RVFand left visual field (LVF] as well as one between-subject condition(healthy, ADHD.Results: The AHDH group showed slower RTs overall (RT=760 msec than the comparisongroup (RT=650 msec ( p = 0.001. RTs in the delayed condition of800 msec (RT=680 msec were faster than in the delayed condition of 100msec (RT=730 msec in all children ( p RTLVF: 830 msec inthe 100 msec delay for the invalid cueing condition ( p = 0.045 that was notfound in the comparison group.Conclusion: General dysfunction including posterior-based covert shift of attention andanterior-based sustained attention was found in ADHD group. Furthermore,asymmetric left parietal dysfunction in the disengaged operation was notedin those with ADHD.

  6. The origins and consequences of attention deficit hyperactivity disorder

    OpenAIRE

    Chang, Zheng

    2013-01-01

    Attention deficit hyperactivity disorder (ADHD) is characterized by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity, and is the most common neurodevelopmental disorder of childhood. This highly prevalent disorder is estimated to affect about 5% of school-age children worldwide, with a substantial degree of persistence over time. Although the specific cause of ADHD is still largely unknown, despite a long history of research, it is believed to involve multip...

  7. Parents Psychopathology of Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Margari, Francesco; Craig, Francesco; Petruzzelli, Maria Giuseppina; Lamanna, Annalinda; Matera, Emilia; Margari, Lucia

    2013-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) is a disorder with extremely complex etiology, not yet well defined but certainly multi-factorial. This study investigated the possible etiopathogenetic role of ADHD symptoms and psychopathology disorders in parents of children with ADHD. We present a case-control study of parents of 50 children…

  8. The Neurological Basis of Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Ballard, Shirley; Bolan, Morna; Burton, Michael; Snyder, Sherry; Pasterczyk-Seabolt, Claire; Martin, Don

    1997-01-01

    Reviews research on attention deficit hyperactivity disorder (ADHD) and examines the role of neurochemical stimulation and signs of neurological deficits. Describes the chemical action of drugs used to treat ADHD, along with cognitive, affective, and behavioral effects, and side effects. Elaborates on drug treatment and basic behavior modification…

  9. Socio-emotional intervention in attention deficit hyperactive disorder

    OpenAIRE

    María Jesús Cardoso-Moreno; Lucía Tomás-Aragonés; César Rodríguez-Ledo

    2015-01-01

    Attention-deficit-hyperactivity disorder (ADHD) is a common neuro-behavioural disorder with onset in childhood. These children have impaired emotional self-control, self-regulation of drive and motivation. Numerous studies have reported cognitive disabilities in memory, executive functions, spatial abilities and language skills. The main objective of this work is to determine whether a socio-emotional intervention programme could improve executive functions in children with Attention Deficit ...

  10. ATTENTION-DEFICIT/HYPERACTIVITY DISORDER DIAGNOSIS AND TREATMENT

    OpenAIRE

    Diana Purnamasari Tanoyo

    2013-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is the most occur neurobehavioral disorder in children, it is also chronically condition that most influence in school children, and it is a disorder of way of thinking that always find in children. ADHD is signed by decrease of attention ability, included increase of distractibilition, and difficulty to defense the attention; difficulty to stronghold impuls control; over activity and restless of motoric. The certain reason of ADHD is not know...

  11. Maternal Anxiety and Attention Deficit Hyperactivity Disorder (ADHD) in Children

    OpenAIRE

    Roohallah Mirzaaghas; Yegane Kohani; Hasan baniasadi; Fateme Tara

    2014-01-01

    Background & aim:  According to the previous studies, anxiety along with some other psychiatric disorders is common among mothers of children with attention deficit hyperactivity disorder (ADHD). Since maternal anxiety affects mother-child interactions, early treatment plays an important role in the prognosis of ADHD in children. This study aimed to determine the relationship between maternal anxiety and hyperactivity in children. Methods: This study was conducted on 112 mothers of ADHD child...

  12. Attention deficit hyperactivity disorder (ADHD): review for primary care clinicians

    OpenAIRE

    Ougrin, Dennis; Chatterton, Sandie; Banarsee, Ricky

    2010-01-01

    Attention deficit hyperactivity disorder (ADHD) is characterised by impulsivity, hyperactivity and inattention. Up to 5% of primary school age children have ADHD. Both genes and environment play a role in the aetiology of ADHD. If left untreated, children with ADHD demonstrate a range of poor long-term psychosocial outcomes. The Strengths and Difficulties Questionnaire (SDQ) may be used to screen children for a range of psychiatric disorders, including ADHD.1

  13. Attention Deficit Hyperactivity Disorder in Korean Juvenile Delinquents.

    Science.gov (United States)

    Chae, Paul Kyuman; Jung, Hyun-Oak; Noh, Kyung-Sun

    2001-01-01

    Identifies attention deficit hyperactivity disorders (ADHD) in Korean juvenile delinquents. Intelligence tests, Test of Variables of Attention, Teacher Report form, Youth Self-Report, and Rosenberg Self Esteem Scale were administered to 98 incarcerated youth and 84 nondelinquent youth. In the delinquent youth, 42.2% of the adolescents were…

  14. Raising attention to attention deficit hyperactivity disorder in schizophrenia.

    Science.gov (United States)

    Pallanti, Stefano; Salerno, Luana

    2015-03-22

    Schizophrenia and attention deficit hyperactivity disorder (ADHD) are two psychiatric disorders with a negative impact on quality of life of individuals affected. Although they are classified into distinct disorders categories, attentional dysfunction is considered as a core feature in both conditions, either at the clinical then pathophysiological level. Beyond the obvious clinical overlap between these disorders, the Research Domain Criteria approach might offer an interesting perspective for disentangling common circuits underpinning both disorders. Hence, we review evidences regarding the overlap between schizophrenia and ADHD, at the clinical level, and at the level of underlying brain mechanisms. The evidence regarding the influence of environmental risk factors in the emergence of both disorders, and their developmental trajectories is also reviewed. Among these, we will try to elucidate the complex relationship between stimulants use and psychotic symptoms, discussing the potential role of ADHD medication in inducing psychosis or in exacerbating it. We aim that, taken together, these findings may promote further investigation with important implications both for clinicians and research. In fact, considering the amounting evidence on the overlap between schizophrenia and ADHD, the delineation of their boundaries might help in the decision for diagnosis and treatment. Moreover, it may help to promote interventions focused on the prevention of both schizophrenia and ADHD, by the reduction of recognized environmental risk factors. PMID:25815254

  15. Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder

    DEFF Research Database (Denmark)

    Plessen, Kerstin J; Bansal, Ravi; Zhu, Hongtu; Whiteman, Ronald; Amat, Jose; Quackenbush, Georgette A; Martin, Laura; Durkin, Kathleen; Blair, Clancy; Royal, Jason; Hugdahl, Kenneth; Peterson, Bradley S

    2006-01-01

    CONTEXT: Limbic structures are implicated in the genesis of attention-deficit/hyperactivity disorder (ADHD) by the presence of mood and cognitive disturbances in affected individuals and by elevated rates of mood disorders in family members of probands with ADHD. OBJECTIVE: To study the morphology...

  16. Measurement of Stigmatization towards Adults with Attention Deficit Hyperactivity Disorder

    NARCIS (Netherlands)

    Fuermaier, Anselm B. M.; Tucha, Lara; Koerts, Janneke; Mueller, Anna K.; Lange, Klaus W.; Tucha, Oliver

    2012-01-01

    Objectives: In general, assessment tools for stigma in mental disorders such as attention deficit hyperactivity disorder (ADHD) are lacking. Moreover, misbeliefs and misconceptions about ADHD are common, in particular with regard to the adult form of ADHD. The aim of the present study was to develop

  17. School-Based Treatment of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Schultz, Brandon K.; Storer, Jennifer; Watabe, Yuko; Sadler, Joanna; Evans, Steven W.

    2011-01-01

    The authors review the research literature regarding school-based treatment of attention-deficit/hyperactivity disorder (ADHD). Students with ADHD often do not receive access to special services, even though the impairments associated with the disorder often compromise learning and cause concerns for classroom teachers, school administrators, and…

  18. An auditable protocol for treating attention deficit/hyperactivity disorder

    OpenAIRE

    Hill, P; Taylor, E.

    2001-01-01

    We present an auditable protocol for attention deficit/hyperactivity disorder (ADHD) or hyperkinetic disorder. The protocol is derived from standard recommendations and evidence, and is intended for outpatient medical clinic practice in secondary care. Suggested side effect rating scales are included.



  19. Intervention for executive functions in attention deficit and hyperactivity disorder

    OpenAIRE

    2015-01-01

    This study aimed to investigate if an executive functions (EF) intervention could promote these skills in individuals with attention deficit and hyperactivity disorder (ADHD). Eighteen children and adolescents, 7-13 years old, divided into experimental (EG, N = 8) and control (CG, N = 10) groups, were assessed in the Block Design and Vocabulary subtests of the WISC III and seven tests of EF. Parents answered two scales, measuring EF and inattention and hyperactivity signs. EG children partici...

  20. Attentional blink in children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Juan A. Amador-Campos

    2015-06-01

    Full Text Available Objective:To explore the temporal mechanism of attention in children with attention deficit hyperactivity disorder (ADHD and controls using a rapid serial visual presentation (RSVP task in which two letters (T1 and T2 were presented in close temporal proximity among distractors (attentional blink [AB].Method:Thirty children aged between 9 and 13 years (12 with ADHD combined type and 18 controls took part in the study. Both groups performed two kinds of RSVP task. In the single task, participants simply had to identify a target letter (T1, whereas in the dual task, they had to identify a target letter (T1 and a probe letter (T2.Results:The ADHD and control groups were equivalent in their single-task performance. However, in the dual-task condition, there were significant between-group differences in the rate of detection of the probe letter (T2 at lag + 1 and lag + 4. The ADHD group exhibited a larger overall AB compared with controls.Conclusion:Our findings provide support for a link between ADHD and attentional blink.

  1. Exposure to attention deficit hyperactivity disorder medications during pregnancy

    OpenAIRE

    Humphreys, Caitlin; Garcia-Bournissen, Facundo; Ito, Shinya; Koren, Gideon

    2007-01-01

    QUESTION An 18-year-old patient of mine, currently under treatment for attention deficit hyperactivity disorder (ADHD) with methylphenidate, just found out that she is pregnant. What are the risks for the baby when the mother uses ADHD medications during pregnancy?

  2. GAME BIOFEEDBACK TECHNOLOGY IN ATTENTION DEFICIT/HYPERACTIVITY DISORDER

    Directory of Open Access Journals (Sweden)

    I. A. Stoller

    2013-01-01

    Full Text Available We continue the study of students with attention deficit hyperactivity disorder when using betastimulating game neurofeedback. The dynamics of segmental characteristics of the alpha rhythm and θ/β ratio for different groups of successful training. Evaluate the effectiveness of training in terms of the number of ADHD symptoms (at the beginning and end of the training.

  3. Very Low Birth Weight and Attention Deficit/Hyperactivity Disorder

    NARCIS (Netherlands)

    van der Meere, Jaap; Börger, Norbert A.; Potgieter, Stephanus Theron; Pirila, Silja; De Cock, Paul

    2009-01-01

    It is well recognized that reaction time performance of term-born children with a normal birth weight (NBW > 2500 g) who fulfill the DSM-IV criteria for attention deficit/hyperactivity disorder (ADHD) in the primary school age is sensitive for the presentation rate of stimuli. They have been found t

  4. Test Anxiety and College Students with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Nelson, Jason M.; Lindstrom, Will; Foels, Patricia A.

    2014-01-01

    Test anxiety was examined in college students with and without attention deficit hyperactivity disorder (ADHD). Results indicated that, relative to college students without ADHD, college students with ADHD reported higher total test anxiety as well as specific aspects of test anxiety, including worry (i.e., cognitive aspects of test anxiety) and…

  5. InforMatrix for attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Janknegt, Robert; Faber, Adrianne; Pereira, Rob Rodrigues; Kalverdijk, Luuk J.

    2009-01-01

    The purpose of this review is to facilitate discussion on drug selection for the treatment of ADHD by using only clinically relevant selection criteria and providing an up-to-date overview. The InforMatrix method was used to select drugs to treat attention deficit hyperactivity disorder (ADHD). The

  6. Exploring five common assumptions on Attention Deficit Hyperactivity Disorder

    NARCIS (Netherlands)

    Batstra, Laura; Nieweg, Edo H.; Hadders-Algra, Mijna

    2014-01-01

    The number of children diagnosed with attention deficit hyperactivity disorder (ADHD) and treated with medication is steadily increasing. The aim of this paper was to critically discuss five debatable assumptions on ADHD that may explain these trends to some extent. These are that ADHD (i) causes de

  7. DSM-5 Further Inflates Attention Deficit Hyperactivity Disorder

    NARCIS (Netherlands)

    Batstra, Laura; Frances, Allen

    2012-01-01

    Since the publication of DSM-IV in 1994, attention deficit hyperactivity disorder (ADHD) prevalence and medication use unexpectedly increased significantly. In this article, we explore the DSM-5 proposals for ADHD that are likely to further increase its prevalence. We also address the possible harmf

  8. Attention-deficit/hyperactivity disorder and social dysfunctioning

    NARCIS (Netherlands)

    Nijmeijer, Judith S.; Minderaa, Ruud B.; Buitelaar, Jan K.; Mulligan, Aisling; Hartman, Catharina A.; Hoekstra, Pieter J.

    2008-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is associated with functional impairments in different areas of daily life. One such area is social functioning. The purpose of this paper is to critically review research on social dysfunctioning in children with ADHD. Children with ADHD often have co

  9. Language Impairment in the Attention-Deficit/Hyperactivity Disorder Context

    Science.gov (United States)

    Redmond, Sean M.

    2016-01-01

    Purpose: Attention-deficit/hyperactivity disorder (ADHD) is a ubiquitous designation that affects the identification, assessment, treatment, and study of pediatric language impairments (LIs). Method: Current literature is reviewed in 4 areas: (a) the capacity of psycholinguistic, neuropsychological, and socioemotional behavioral indices to…

  10. The Effect of Multimodal Trainings on Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Kaymak Özmen, Suna; Kafkas Üniversitesi, Eğitim Fakültesi, Eğitim Bilimleri Bölümü

    2011-01-01

    In this study, the effect of parent, teacher and attention training programs for daily problem behaviors of a child with Attention Deficit Hyperactivity Disorder (ADHD) was analyzed through parent and teacher evaluations. To achieve this purpose, single case study was employed. At the beginning of the study, baseline data were gathered both at home and in school. When the baseline data was decided to be decisive, parent training, teacher training and attention training programs were applied c...

  11. Diagnosing and treating attention-deficit/hyperactivity disorder in adults

    OpenAIRE

    Faraone, Stephen V.; Antshel, Kevin M.

    2008-01-01

    Adult attention deficit/hyperactivity disorder (ADHD) is a valid and impairing psychiatric disorder. In this article, we review the diagnosis of ADHD in adults, focusing on symptom presentation differences between pediatric and adult ADHD as well as the importance of assessing functional impairments. Differentiating ADHD from other clinical disorders is often the most difficult part of making an ADHD diagnosis in adults. Psychiatric comorbidities are also described and discussed as potential ...

  12. Early detection and intervention for attention-deficit/hyperactivity disorder

    OpenAIRE

    Barke, Edmund; Koerting, J; Smith, E.; McCann, DC; Thompson, M.

    2011-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a high-cost/high-burden disorder. Early detection and intervention may prevent or ameliorate the development of the disorder and reduce its long-term impact. In this article, we set out a rationale for an early detection and intervention program. First, we highlight the costs of the condition and second, we discuss the limitations of the current treatments. We then outline the potential value of an early detection and intervention program. We...

  13. Transcranial Magnetic Stimulation Measures in Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Wu, Steve W.; Gilbert, Donald L.; Shahana, Nasrin; HUDDLESTON, DAVID A; Mostofsky, Stewart H.

    2012-01-01

    Children affected by Attention-Deficit/Hyperactivity Disorder have diminished intra-hemispheric inhibition (Short Interval Cortical Inhibition) as measured by Transcranial Magnetic Stimulation. This study’s objective is to determine whether inter-hemispheric inhibition (Ipsilateral Silent Period Latency) correlates with clinical behavioral rating and motor control deficits of affected children. In 114 8–12 year old, right-handed children (age/sex-matched, 50 affected, 64 controls), we perform...

  14. Understanding Attention Deficit Disorders.

    Science.gov (United States)

    Villegas, Orlando; And Others

    This booklet provides basic information regarding attention deficit hyperactivity disorders (ADHD), in their separate modalities, with hyperactivity, impulsivity, and inattention. Explanations are offered concerning short attention span, impulsive behavior, hyperactivity, and beginning new activities before completing the previous one. Theories…

  15. Advances and Considerations in Attention-Deficit/Hyperactivity Disorder Pharmacotherapy

    OpenAIRE

    Shahin Akhondzadeh; Mohammad Mohammadi

    2011-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric disorder associated with significant impairments in occu¬pational, academic, neuropsychological, and social functioning. Central nervous system (CNS) stimulants are recommended as first-line medication therapy for children. CNS stimulants include formulations of methylphenidate and amphetamine derivatives and are available in a large variety of immediate- and extended-release preparations. Extended-release ...

  16. Adult attention deficit hyperactivity disorder is associated with asthma

    OpenAIRE

    Halmøy Anne; Fasmer Ole; Eagan Tomas; Oedegaard Ketil; Haavik Jan

    2011-01-01

    Abstract Background Attention deficit hyperactivity disorder (ADHD) is increasingly recognized as a common disorder not only in children, but also in the adult population. Similarly, asthma also has a substantial prevalence among adults. Previous studies concerning a potential relationship between ADHD and asthma have not presented consistent results. Methods A cross-sectional study of 594 adult patients diagnosed with ADHD, compared with 719 persons from the general population. Information w...

  17. Adult attention deficit hyperactivity disorder is associated with asthma

    OpenAIRE

    Fasmer, Ole Bernt; Halmøy, Anne; Eagan, Tomas Mikal; Ødegaard, Ketil Joachim; Haavik, Jan

    2011-01-01

    Background: Attention deficit hyperactivity disorder (ADHD) is increasingly recognized as a common disorder not only in children, but also in the adult population. Similarly, asthma also has a substantial prevalence among adults. Previous studies concerning a potential relationship between ADHD and asthma have not presented consistent results. Methods: A cross-sectional study of 594 adult patients diagnosed with ADHD, compared with 719 persons from the general population. Infor...

  18. ATTENTION DEFICIT HYPERACTIVITY DISORDER: COMORBIDITIES, EMPHASIS ON CONCURRENCE WITH EPILEPSY

    OpenAIRE

    O. A. Pylaeva; A A Shatenshtein; M. Yu. Dorofeeva; K. Yu. Mukhin

    2015-01-01

    Attention deficit hyperactivity disorder (ADHD) is the most common cause of behavioral disorders and learning problems at preschool and school ages. Patients with ADHD are frequently found to have comorbidities that present additional diagnostic and therapeutic problems and result in an even greater decrease in quality of life in patients. Thus, ADHD is frequently concurrent with epilepsy; in this case, not only the manifestations of ADHD are more common in epilepsy, but the latter is more of...

  19. Stigmatization in teachers towards adults with attention deficit hyperactivity disorder

    OpenAIRE

    Fuermaier, Anselm BM; Tucha, Lara; Mueller, Anna K.; Koerts, Janneke; Hauser, Joachim; Lange, Klaus W.; Tucha, Oliver

    2014-01-01

    Objectives Attention deficit hyperactivity disorder (ADHD) is understood as a developmental disorder which shares common characteristics between childhood, adolescence and adulthood. However, ADHD is widely associated with misconceptions and misbeliefs which can lead to stigmatization. Teachers have an important role for the individual development as they accompany students for a long period of time. The aim of the present study was to explore stigmatizing attitudes in teachers towards adults...

  20. Neuroscience of attention deficit hyperactivity disorder (ADHD)- a review

    OpenAIRE

    Haile D.B; Mohammed S

    2013-01-01

    Attention Deficit Hyperactivity disorder (ADHD) does not have a single underlying pathophysiology which seems it has a multifaceted etiology. There are various contributing factors for ADHD, environmental and genetic being few of them. This neurobiological disorder has been a result of continuous actions of the risk factors. Neuroimaging study has indicated that children suffering from ADHD had immature brains compared to other children. This has pointed towards the fact that the Cerebellum, ...

  1. Association of attention-deficit/hyperactivity disorder with gambling disorder.

    Science.gov (United States)

    Retz, Wolfgang; Ringling, Jutta; Retz-Junginger, Petra; Vogelgesang, Monika; Rösler, Michael

    2016-08-01

    Attention-deficit/hyperactivity disorder (ADHD) is a frequent mental disorder with childhood onset and high persistence into adulthood. There is much evidence that ADHD increases the risk for the development of other psychiatric disorders and functional problems in several domains of everyday life. In this study, the association of ADHD with gambling disorder (GD) was investigated. 163 adult subjects suffering from GD were examined for childhood and current ADHD according to DSM-5 as well as co-morbid psychiatric disorders. Moreover, characteristics of gambling behavior have been evaluated. The prevalence of lifetime ADHD was 28.8 %, with 25.2 % of the study population presenting ADHD as a full syndrome according to DSM-5. The prevalence of co-morbid substance use disorders and adjustment disorders and cluster B personality disorders was higher in GD patients with current ADHD than in the group without. Also, an increased rate of suicide attempts was detected in gamblers with ADHD. In contrast with gamblers without ADHD, those with ADHD were reported to spend more time with gambling, a sedative effect of gambling and a faster development of GD. The high prevalence of ADHD in patients with GD indicates that childhood ADHD is a risk factor for the development of GD in later life. Moreover, treatment of patients with GD and ADHD is complicated by a high rate of co-morbid disorders. Regarding therapeutic approaches, it should be considered that functional aspects of gambling differ in GD patients with and without ADHD. PMID:27328979

  2. Treatment of adults with attention-deficit/hyperactivity disorder

    OpenAIRE

    Hechtman, Lily

    2008-01-01

    Dusan Kolar, Amanda Keller, Maria Golfinopoulos, Lucy Cumyn, Cassidy Syer, Lily HechtmanDepartment of Psychiatry, Montreal Children’s Hospital, McGill University, Montreal, CanadaAbstract: This review focuses on the treatment of attention deficit hyperactivity disorder (ADHD) in adults. It briefly addresses prevalence, diagnostic and differential diagnostic issues specific to adults. Stimulant medication, non-stimulant medication, and psychosocial treatments are thoroughly reviewed....

  3. Dietary Patterns and Attention Deficit Hyperactivity Disorder among Iranian Children

    OpenAIRE

    Leila Azadbakht; Mohammad H. Rouhani; Ahmad Esmaillzadeh

    2012-01-01

    Background: : To evaluate the association of major dietary patterns identified by factor analysis and attention deficit hyperactivity disorder (ADHD) in a group of Iranian school aged children.Materials and Method: : This cross-sectional study was conducted among 375 school-aged children in Tehran, Iran. Usual dietary intakes were assessed by a semi-quantitative food frequency questionnaire. DSM-IV questionnaire was used to determine the prevalence of ADHD. Major dietary patterns were ident...

  4. Reduced white matter integrity in attention-deficit hyperactivity disorder

    OpenAIRE

    Hamilton, Liberty S.; Levitt, Jennifer G; O’Neill, Joseph; Alger, Jeffry R; Luders, Eileen; Phillips, Owen R.; Caplan, Rochelle; Toga, Arthur W.; McCracken, James; Narr, Katherine L.

    2008-01-01

    We used diffusion tensor imaging to investigate fractional anisotropy (FA), a measure of fiber tract integrity, in attention-deficit hyperactivity disorder (ADHD). Using a tract-based atlasing approach on six-direction diffusion tensor imaging data, we examined FA within the cingulum, corpus callosum, corticospinal tract, fornix, optic radiations, superior longitudinal fasciculus, uncinate fasciculus, and the superior and inferior occipitofrontal fasciculi in an all-male sample of17 children ...

  5. Intellectual Disability in Children with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Ahuja, Alka; Martin, Joanna; Langley, Kate; Thapar, Anita

    2013-01-01

    Objective To determine whether children with attention deficit hyperactivity disorder (ADHD) and mild intellectual disability (ID) are a clinically distinct ADHD subgroup. Study design This was a cross-sectional study comparing clinical characteristics (ADHD subtypes, total number of symptoms, and rates of common comorbidities) between children with ADHD and mild ID and those with ADHD and IQ test scores >70, and also between children with ADHD and ID and a general population sample of childr...

  6. Attention deficit hyperactivity disorder symptoms mediate early-onset smoking

    OpenAIRE

    Huizink, Anja; Lier, P.A.C.; Crijnen, Alfons

    2008-01-01

    textabstractBackground/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based, randomized controlled intervention trial, we examined whether intervention-induced reductions in ADHD symptoms at age 9 mediated the reduced risk of tobacco use onset among these children at age 10...

  7. A framework of psychological compensation in attention deficit hyperactivity disorder

    OpenAIRE

    Merkt, Julia; Reinelt, Tilman; Petermann, Franz

    2015-01-01

    The term compensation is widely used in the context of attention deficit hyperactivity disorder (ADHD), yet, it is neither defined nor theory driven. Adapting a model of psychological compensation (Bäckman and Dixon, 1992) to fit ADHD research is the aim of this review: we will (1) introduce the existing theoretical framework of psychological compensation, (2) discuss its applicability to ADHD and adapt the model to fit ADHD research, and (3) set up requirements for research on psychological ...

  8. Attention-deficit/hyperactivity disorder in postsecondary students

    OpenAIRE

    Murkett, Katharine

    2014-01-01

    Kevin Nugent,1 Wallace Smart2,3 1Kinark Child and Family Services, Trent University and Sir Sanford Fleming College, Peterborough, ON, Canada; 2Department of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; 3University of Lethbridge Health Centre, Lethbridge, AB, Canada Abstract: A PubMed review was conducted for papers reporting on attention-deficit/ hyperactivity disorder (ADHD) in postsecondary students. The review was performed in order to determ...

  9. Attention deficit hyperactivity disorder presenting as dermatitis artefacta

    Directory of Open Access Journals (Sweden)

    Suravi Patra

    2016-01-01

    Full Text Available Dermatitis artefacta, a self-inflicted intentional dermatosis is a very rare diagnosis in childhood. In a large proportion, the underlying psychiatric disorders go unidentified due to lack of collaboration between dermatologist and psychiatrist. The underlying psychological reasons for childhood dermatitis artefacta include emotional distress and interpersonal conflicts. A multitude of psychosocial factors interact to precipitate this disorder. Here, we report a child with dermatitis artefacta who was diagnosed with attention deficit hyperactivity disorder during psychiatric evaluation. Parental expectations and sibling rivalry were further increasing the stress of the index child. Appropriate diagnosis and management lead to treatment compliance and functional improvement in the child.

  10. Attention deficit hyperactivity disorder presenting as dermatitis artefacta.

    Science.gov (United States)

    Patra, Suravi; Sirka, Chandra Sekhar

    2016-01-01

    Dermatitis artefacta, a self-inflicted intentional dermatosis is a very rare diagnosis in childhood. In a large proportion, the underlying psychiatric disorders go unidentified due to lack of collaboration between dermatologist and psychiatrist. The underlying psychological reasons for childhood dermatitis artefacta include emotional distress and interpersonal conflicts. A multitude of psychosocial factors interact to precipitate this disorder. Here, we report a child with dermatitis artefacta who was diagnosed with attention deficit hyperactivity disorder during psychiatric evaluation. Parental expectations and sibling rivalry were further increasing the stress of the index child. Appropriate diagnosis and management lead to treatment compliance and functional improvement in the child. PMID:27195043

  11. [Assessment of the attention-deficit hyperactivity disorder in adults].

    Science.gov (United States)

    Gross, J; Blocher, D; Trott, G E; Rösler, M

    1999-01-01

    The attention-deficit hyperactivity disorder (ADHD) is one of the most common disorders in childhood and adolescence with a prevalence of app. 5%. The importance of ADHD in childhood as a factor of vulnerability for psychiatric disorders in adults is becoming a focus of discussion. It was shown that there is a comorbidity in adults with substance abuse, delinquency and personality disorders. There is a growing evidence that ADHD will persist in a significant number of patients during adulthood. This is the first german study to evaluate this interdependence. We examined 164 adult inpatients and 48 healthy volunteers with the Wender Utah Rating Scale (WURS), a retrospective self-evaluation scale for the diagnosis of ADHD in childhood, and the Eysenck impulsiveness questionnaire I7. It could be shown that the WURS and the I7 are suitable instruments for the evaluation of the ADHD in adults especially concerning the aspects of attention deficits and impulsiveness. PMID:10087514

  12. Story Comprehension and Academic Deficits in Children with Attention Deficit Hyperactivity Disorder: What Is the Connection?

    Science.gov (United States)

    Berthiaume, Kristen S.

    2006-01-01

    Based on the reliable findings that children with attention deficit hyperactivity disorder (ADHD) have both attentional and academic difficulties, it is assumed that the attentional deficit contributes to the academic problems. In this article, existing support for a link between the attentional and academic difficulties experienced by children…

  13. Drug therapy of attention deficit hyperactivity disorder: Current trends

    Directory of Open Access Journals (Sweden)

    Avinash De Sousa

    2012-01-01

    Full Text Available Attention deficit hyperactivity disorder is a developmental disorder with an age onset prior to 7 years. Children with ADHD have significantly lower ability to focus and sustain attention and also score higher on impulsivity and hyperactivity. Stimulants, such as methylphenidate, have remained the mainstay of ADHD treatment for decades with evidence supporting their use. However, recent years have seen emergence of newer drugs and drug delivery systems, like osmotic release oral systems and transdermal patches, to mention a few. The use of nonstimulant drugs like atomoxetine and various other drugs, such as a-agonists, and a few antidepressants, being used in an off-label manner, have added to the pharmacotherapy of ADHD. This review discusses current trends in drug therapy of ADHD and highlights the promise pharmacogenomics may hold in the future.

  14. Attentional Profiles and White Matter Correlates in Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Type

    OpenAIRE

    Rossi, Adriana Suzart Ungaretti; de Moura, Luciana Monteiro; de Mello, Claudia Berlim; de Souza, Altay Alves Lino; Muszkat, Mauro; Bueno, Orlando Francisco Amodeo

    2015-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a widely studied neurodevelopmental disorder. It is a highly heterogeneous condition, encompassing different types of expression. The predominantly inattentive type is the most prevalent and the most stable over the lifetime, yet it is the least-studied presentation. To increase understanding of its cognitive profile, 29 children with attention-deficit/hyperactivity disorder of predominantly inattentive type (ADHD-I) and 29 matched controls, ...

  15. Adult attention deficit hyperactivity disorder is associated with migraine headaches

    OpenAIRE

    Fasmer, Ole Bernt; Halmøy, Anne; Ødegaard, Ketil Joachim; Haavik, Jan

    2011-01-01

    Attention deficit hyperactivity disorder (ADHD) is now recognized as a common disorder both in child and adult psychiatry. Adult patients with a diagnosis of ADHD (n = 572) and community controls (n = 675) responded to auto-questionnaires rating past and present symptoms of ADHD, co-morbid conditions, including migraine, treatment history and work status. The prevalence of migraine was significantly higher in the patient group compared to the controls (28.3% vs. 19.2%, P 

  16. Oculomotor Anomalies in Attention-Deficit/Hyperactivity Disorder: Evidence for Deficits in Response Preparation and Inhibition

    Science.gov (United States)

    Mahone, E. Mark; Mostofsky, Stewart H.; Lasker, Adrian G.; Zee, David; Denckla, Martha B.

    2009-01-01

    Girls, but not boys, with attention deficit hyperactivity disorder (ADHD) have significantly longer visually guided saccades latencies. It is found that sex differences in children with ADHD extend beyond symptom presentation to the development of oculomotor control.

  17. Intervention for executive functions in attention deficit and hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Amanda Menezes

    2015-03-01

    Full Text Available This study aimed to investigate if an executive functions (EF intervention could promote these skills in individuals with attention deficit and hyperactivity disorder (ADHD. Eighteen children and adolescents, 7-13 years old, divided into experimental (EG, N = 8 and control (CG, N = 10 groups, were assessed in the Block Design and Vocabulary subtests of the WISC III and seven tests of EF. Parents answered two scales, measuring EF and inattention and hyperactivity signs. EG children participated in a program to promote EF in twice-weekly group sessions of one hour each. After 8 months of intervention, groups were assessed again. ANCOVA, controlling for age, intelligence quotient and pretest performance, revealed gains in attention/inhibition and auditory working memory measures for the EG. No effect was found for scales or measures of more complex EF. Results are not conclusive, but they illustrate some promising data about EF interventions in children and adolescents with ADHD.

  18. Functional imaging of neurocognitive dysfunction in attention deficit hyperactivity disorder

    International Nuclear Information System (INIS)

    Attention Deficit Hyperactivity Disorder (ADHD) is a neurobiological disorder of early childhood onset. Defining symptoms are chronic impairments of attention, impulse control and motor hyperactivity that frequently persist until adulthood. Miscellaneous causes of the disorder have been discussed. Accumulating evidence from imaging- and molecular genetic studies strengthened the theory of ADHS being a predominantly inherited disorder of neurobiological origin. In the last 15 years, non-invasive brain imaging methods were successfully implemented in pediatric research. Functional magnetic resonance imaging studies gave major insight into the neurobiological correlates of executive malfunction, inhibitory deficits and psychomotoric soft signs. These findings are in good accordance with brain morphometric data indicating a significant volumetric decrease of major components of striato-thalamo-cortical feedback loops, primarily influencing prefrontal executive functioning (e.g. basal ganglia). Empirical evidence points to a broad array of associated behavioral disturbances like deficient visuomotor abilities and oculomotor dysfunctions. This paper reviews the current empirical evidence derived from prior imaging studies. Special emphasis is given to the relevance of oculomotor dysfunctions in clinical and research settings, as well as their assessment in the MR environment. (orig.)

  19. Drug holidays and attention deficit/hyperactivity disorder

    Institute of Scientific and Technical Information of China (English)

    Christopher P. SZABO

    2011-01-01

    The concept of ‘drug holidays’ (defined as "...the structured interruption of pharmacological treatment..."[1]) in the management of attention deficit hyperactivity disorder (ADHD) is well established,but poorly researched[1].The question is whether there is indeed a justifiable basis for the practice.In the opinion piece by Professors Du and Wang[2],they argue that on the balance of available evidence it is not justified.Herein lies the issue-the evidence.In reality significant numbers of parents both report side effects[3] and stop medication intermittently[1],and many sufferers stop treatment prematurely[4] (generally due to adverse effects).

  20. Psychosocial treatments for attention-deficit/hyperactivity disorder in children.

    Science.gov (United States)

    Barkley, Russell A

    2002-01-01

    This article provides a brief overview of the major psychosocial treatments that have some efficacy for the management of attention-deficit/hyperactivity disorder (ADHD) in children. Parent training in effective child behavior management methods, classroom behavior modification methods and academic interventions, and special educational placement appear to have the greatest promise of efficacy. Augmenting these, additional family therapy in problem-solving and communication skills and the coordination of multiple school resources across the day may be necessary. To be effective in improving prognosis, treatments must be maintained over extended periods of time. PMID:12562060

  1. Psychosocial interventions in attention-deficit/hyperactivity disorder: update.

    Science.gov (United States)

    Antshel, Kevin M

    2015-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is the most common reason for referral to child and adolescent psychiatry clinics. Although stimulant medications represent an evidence-based approach to managing ADHD, psychosocial interventions for child/adolescent ADHD target functional impairments as the intervention goal, and rely heavily on behavioral therapy techniques and operant conditioning principles. Evidence-based psychosocial interventions for managing pediatric ADHD include behavioral parent training, school-based interventions relying on behavioral modification, teaching skills, and operant conditioning principles, and intensive summer treatment programs. The use of conjoint psychosocial treatments with ADHD medications may enable lower doses of each form of treatment. PMID:25455577

  2. Socio-emotional intervention in attention deficit hyperactive disorder

    Directory of Open Access Journals (Sweden)

    María Jesús Cardoso-Moreno

    2015-06-01

    Full Text Available Attention-deficit-hyperactivity disorder (ADHD is a common neuro-behavioural disorder with onset in childhood. These children have impaired emotional self-control, self-regulation of drive and motivation. Numerous studies have reported cognitive disabilities in memory, executive functions, spatial abilities and language skills. The main objective of this work is to determine whether a socio-emotional intervention programme could improve executive functions in children with Attention Deficit Hyperactivity Disorder. The sample of this study consisted of 25 children (8 female and 17 male aged between 8 and 12 years, diagnosed with ADHD and who were not taking any psychopharmacological treatment at the time of the study, and had not taken medication previously. Executive functioning was assessed through the Zoo Map test and Tower of Hanoi puzzle in pre-/post-test design. A socio-emotional intervention programme was implemented. The training consisted of 8 one-hour weekly sessions, on an individual basis. Results indicate that such a programme does lead to improved performance in the execution of tasks that evaluate executive functions. After the intervention, the children took less time to resolve the Zoo Map test. Results for the Hanoi Tower puzzle were also improved after intervention. The children needed a lower number of movements to complete the task.

  3. Cognitive control in adults with attention-deficit/hyperactivity disorder

    DEFF Research Database (Denmark)

    Dramsdahl, Margaretha; Westerhausen, René; Haavik, Jan;

    2011-01-01

    The objective of the present study was to investigate the ability of adults with Attention-Deficit/Hyperactivity Disorder (ADHD) to direct their attention and exert cognitive control in a forced instruction dichotic listening (DL) task. The performance of 29 adults with ADHD was compared with 58......-forced condition), or to focus and report either the right- or left-ear syllable (forced-right and forced-left condition). This procedure is presumed to tap distinct cognitive processes: perception (non-forced condition), orienting of attention (forced-right condition), and cognitive control (forced-left condition......). Adults with ADHD did not show significant impairment in the conditions tapping perception and attention orientation, but were significantly impaired in their ability to report the left-ear syllable during the forced-left instruction condition, whereas the control group showed the expected left...

  4. Attention deficit hyperactivity disorder: A review for family physicians

    Directory of Open Access Journals (Sweden)

    Karande Sunil

    2005-12-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is a chronic behavioral disorder characterized by persistent hyperactivity, impulsivity, and inattention that impairs educational achievement and/or social functioning. Its diagnosis is made by ascertaining whether the child′s specific behaviors meet the diagnostic and statistical manual of mental disorders-IV-revised criteria. Its etiology is still unclear but recent studies suggest that genetics plays a major role in conferring susceptibility. Comorbidity with psychiatric disorders such as anxiety disorder, depression, oppositional defiant disorder and conduct disorder; and with specific learning disability is not uncommon. Although medication works well in most cases of ADHD, optimal treatment requires integrated medical and behavioral treatment. Methylphenidate (MPH and atomoxetine are the two drugs being currently prescribed and their efficacy in decreasing the symptoms of ADHD is well documented. Pyschoeducational interventions in school can help increase the successful functioning of affected children and improve their academic performance. Almost half of affected children continue to show significant symptoms of the disorder into adolescence and young adulthood. The family physician can play an important role in detecting this condition early, coordinating its assessment and treatment, counseling the parents and classroom teacher, and monitoring the child′s academic and psychosocial progress on a long-term basis.

  5. Melatonin effects on sleep disorders in children with attention deficit hyperactivity disorder

    OpenAIRE

    Zahra Bahremand; Peyman Hashemian; Fatemeh Moharreri; Ehsan Soltani

    2014-01-01

    Attention deficit hyperactivity disorder is one of the most common psychiatric disorders in childhood. Around 25-50% of these children suffered from some kind of sleep disorder especially with chronic form of insomnia. The physicians usually have a plan for improving hyperactivity and attention deficit of this disease but unfortunately, they forget to manage the sleep disorders, which are a major part of patients’ problems.Nowadays, we know that there is a noticeable relationship between atte...

  6. Gendering attention deficit hyperactivity disorder: a discursive analysis of UK newspaper stories

    OpenAIRE

    Horton-Salway, Mary

    2013-01-01

    Discursive psychology is used to study the gendering of attention deficit hyperactivity disorder in UK national newspapers in the period of 2009-11. The analysis examines how gendering is embedded in causal attributions and identity constructions. Attention deficit hyperactivity disorder is portrayed as a predominantly male phenomemon with representations of attention deficit hyperactivity disorder being gendered through extreme stories about victims, villains or heroes that depict boys and m...

  7. Attention deficit hyperactivity disorder, CNS stimulants and sport.

    Science.gov (United States)

    Hickey, G; Fricker, P

    1999-01-01

    Attention deficit hyperactivity disorder (ADHD) affects 1 to 10% of children and is characterised by a persistent pattern of inattention and/or hyperactivity/impulsivity. Over one-half of children with ADHD have associated conditions, including learning disabilities, conduct disorders, poor coordination, depression, anxiety, obsessive-compulsive disorders and bipolar disorders. CNS stimulant medication used in the management of ADHD is not permitted for use in competition by the International Olympic Committee (IOC) and this poses a problem for the physicians of patients with ADHD. On the one hand, attention and concentration are improved by stimulant medication and fine motor coordination and balance are improved after methylphenidate administration, but these therapeutic and sport-related benefits are not available to the athlete with ADHD who wishes to compete under IOC rules. It has been suggested that treatment with methylphenidate may be suitable for athletes with ADHD, as cessation of therapy 24 hours before competition is usually adequate to allow drug clearance which should avoid a positive result being returned on drug testing. More research is needed to establish whether stimulant medication for athletes with ADHD provides an unfair advantage in competition. PMID:10028130

  8. Attention Deficit Hyperactivity Disorder and Sensory Modulation Disorder: A Comparison of Behavior and Physiology

    Science.gov (United States)

    Miller, Lucy Jane; Nielsen, Darci M.; Schoen, Sarah A.

    2012-01-01

    Children with attention deficit hyperactivity disorder (ADHD) are impulsive, inattentive and hyperactive, while children with sensory modulation disorder (SMD), one subtype of Sensory Processing Disorder, have difficulty responding adaptively to daily sensory experiences. ADHD and SMD are often difficult to distinguish. To differentiate these…

  9. [Autism and attention deficit hyperactivity disorder: pharmacological intervention].

    Science.gov (United States)

    Fernández-Jaén, Alberto; Martín Fernández-Mayoralas, Daniel; Fernández-Perrone, Ana Laura; Calleja-Pérez, Beatriz; Muñoz-Jareño, Nuria; López-Arribas, Sonia

    2013-09-01

    The cardinal symptoms of attention deficit hyperactivity disorder (ADHD)--inattention, hyperactivity and impulsiveness--are not specific and may be found in the general population and in other disorders. These symptoms are present in over 50% of patients with autism spectrum disorders (ASD). It thus seems quite clear that both problems can coexist in these patients. The usual pharmacological treatments for ADHD, methylphenidate and atomoxetine, appear to be useful in reducing the above-mentioned symptoms in patients with ADHD and ASD. Effectiveness seems to be lower in patients with ASD and tolerance is slightly poorer. This may be conditioned by a number of variables, including: the complexity of ASD, association with mental retardation, polypharmacotherapy, and so on. Given the long-term tolerance profile of methylphenidate and atomoxetine, these treatments appear to be a good alternative with which to improve the problems of attention and self-control these patients have. Nevertheless, further controlled studies are needed to confirm this proposition. PMID:23897149

  10. A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Craig F

    2016-05-01

    Full Text Available Francesco Craig,1 Francesco Margari,2 Anna R Legrottaglie,1 Roberto Palumbi,1 Concetta de Giambattista,1 Lucia Margari1 1Child Neuropsychiatry Unit, 2Psychiatry Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari “Aldo Moro”, Bari, Italy Abstract: Executive dysfunction has been shown to be a promising endophenotype in neurodevelopmental disorders such as autism spectrum disorder (ASD and attention-deficit/hyperactivity disorder (ADHD. This article reviewed 26 studies that examined executive function comparing ASD and/or ADHD children. In light of findings from this review, the ASD + ADHD group appears to share impairment in both flexibility and planning with the ASD group, while it shares the response inhibition deficit with the ADHD group. Conversely, deficit in attention, working memory, preparatory processes, fluency, and concept formation does not appear to be distinctive in discriminating from ASD, ADHD, or ASD + ADHD group. On the basis of neurocognitive endophenotype, the common co-occurrence of executive function deficits seems to reflect an additive comorbidity, rather than a separate condition with distinct impairments. Keywords: executive function, autism spectrum disorder, attention-deficit/hyperactivity disorder, ASD + ADHD, neurocognitive endophenotype

  11. A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Craig, Francesco; Margari, Francesco; Legrottaglie, Anna R; Palumbi, Roberto; de Giambattista, Concetta; Margari, Lucia

    2016-01-01

    Executive dysfunction has been shown to be a promising endophenotype in neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). This article reviewed 26 studies that examined executive function comparing ASD and/or ADHD children. In light of findings from this review, the ASD + ADHD group appears to share impairment in both flexibility and planning with the ASD group, while it shares the response inhibition deficit with the ADHD group. Conversely, deficit in attention, working memory, preparatory processes, fluency, and concept formation does not appear to be distinctive in discriminating from ASD, ADHD, or ASD + ADHD group. On the basis of neurocognitive endophenotype, the common co-occurrence of executive function deficits seems to reflect an additive comorbidity, rather than a separate condition with distinct impairments. PMID:27274255

  12. Treatment of adults with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Dusan Kolar

    2008-03-01

    Full Text Available Dusan Kolar, Amanda Keller, Maria Golfinopoulos, Lucy Cumyn, Cassidy Syer, Lily HechtmanDepartment of Psychiatry, Montreal Children’s Hospital, McGill University, Montreal, CanadaAbstract: This review focuses on the treatment of attention deficit hyperactivity disorder (ADHD in adults. It briefly addresses prevalence, diagnostic and differential diagnostic issues specific to adults. Stimulant medication, non-stimulant medication, and psychosocial treatments are thoroughly reviewed. For each class of medication possible mechanism of action, efficacy and side effects are summarized. Special attention is given to the pharmacological treatment for patients with adult ADHD and various comorbidities. In summary, stimulant medications are most effective and combined medication and psychosocial treatment is the most beneficial treatment option for most adult patients with ADHD.Keywords: adult ADHD, medication, stimulants, cognitive-behavioral therapy

  13. Treatment of adults with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Dusan Kolar

    2008-04-01

    Full Text Available Dusan Kolar, Amanda Keller, Maria Golfinopoulos, Lucy Cumyn, Cassidy Syer, Lily HechtmanDepartment of Psychiatry, Montreal Children’s Hospital, McGill University, Montreal, CanadaAbstract: This review focuses on the treatment of attention deficit hyperactivity disorder (ADHD in adults. It briefly addresses prevalence, diagnostic and differential diagnostic issues specific to adults. Stimulant medication, non-stimulant medication, and psychosocial treatments are thoroughly reviewed. For each class of medication possible mechanism of action, efficacy and side effects are summarized. Special attention is given to the pharmacological treatment for patients with adult ADHD and various comorbidities. In summary, stimulant medications are most effective and combined medication and psychosocial treatment is the most beneficial treatment option for most adult patients with ADHD.Keywords: adult ADHD, medication, stimulants, cognitive-behavioral therapy

  14. Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder

    DEFF Research Database (Denmark)

    Plessen, Kerstin J; Bansal, Ravi; Zhu, Hongtu;

    2006-01-01

    CONTEXT: Limbic structures are implicated in the genesis of attention-deficit/hyperactivity disorder (ADHD) by the presence of mood and cognitive disturbances in affected individuals and by elevated rates of mood disorders in family members of probands with ADHD. OBJECTIVE: To study the morphology...... of the hippocampus and amygdala in children with ADHD. DESIGN: A cross-sectional case-control study of the hippocampus and amygdala using anatomical magnetic resonance imaging. SETTINGS: University research institute. PATIENTS: One hundred fourteen individuals aged 6 to 18 years, 51 with combined......-type ADHD and 63 healthy controls. MAIN OUTCOME MEASURES: Volumes and measures of surface morphology for the hippocampus and amygdala. RESULTS: The hippocampus was larger bilaterally in the ADHD group than in the control group (t = 3.35; P <.002). Detailed surface analyses of the hippocampus further...

  15. Executive and attentional contributions to Theory of Mind deficit in attention deficit/hyperactivity disorder (ADHD).

    Science.gov (United States)

    Mary, Alison; Slama, Hichem; Mousty, Philippe; Massat, Isabelle; Capiau, Tatiana; Drabs, Virginie; Peigneux, Philippe

    2016-01-01

    Attention deficit/hyperactivity disorder (ADHD) in children has been associated with attentional and executive problems, but also with socioemotional difficulties possibly associated with deficits in Theory of Mind (ToM). Socioemotional problems in ADHD are associated with more negative prognoses, notably interpersonal, educational problems, and an increased risk of developing other psychiatric disorders that emphasize the need to clarify the nature of their ToM deficits. In this study, we hypothesized that ToM dysfunction in children with ADHD is largely attributable to their attentional and/or executive deficits. Thirty-one children with ADHD (8-12 years, IQ > 85) and 31 typically developing (TD) children were assessed using executive functions (inhibition, planning, and flexibility) and attentional tasks, as well as two advanced ToM tasks (Reading the Mind in the Eyes and Faux Pas) involving different levels of executive control. Children with ADHD performed more poorly than TD children in attentional, executive function, and ToM tasks. Linear regression analyses conducted in the ADHD group indicated that inhibition scores predicted performance on the "Faux Pas" task the best, while attention scores were the best for predicting performance on the Reading the Mind in the Eyes task. When controlled for inhibition and attentional variables, ToM performance in children with ADHD was actually similar to TD children. Contrarily, controlling for ToM scores did not normalize performance for inhibition and attentional tasks in children with ADHD. This unidirectional relationship suggests that deficits in the EF and attentional domains are responsible for ToM deficits in ADHD, which therefore may contribute to their socioemotional difficulties. PMID:25763856

  16. Neuroimaging of tic disorders with co-existing attention-deficit/hyperactivity disorder

    DEFF Research Database (Denmark)

    Plessen, Kerstin J; Royal, Jason M; Peterson, Bradley S

    BACKGROUND: Tourette syndrome (TS) and Attention-Deficit/Hyperactivity Disorder (ADHD) are common and debilitating neuropsychiatric illnesses that typically onset in the preschool years. Recently, both conditions have been subject to neuroimaging studies, with the aim of understanding their...

  17. Oculomotor Performance Identifies Underlying Cognitive Deficits in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Loe, Irene M.; Feldman, Heidi M.; Yasui, Enami; Luna, Beatriz

    2009-01-01

    The evaluation of the cognitive control in children with attention-deficit hyperactivity disorder through the use of oculomotor tests reveal that this group showed susceptibility to peripheral distractors and deficits in response inhibition. All subjects were found to have intact sensorimotor function and working memory.

  18. Antidepressants in the treatment of attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Popper, C W

    1997-01-01

    Antidepressants differ in their effectiveness for treating attention-deficit/hyperactivity disorder (ADHD) in adults and children. None are as effective as psychostimulants for treating the attentional and cognitive symptoms, but they can help reduce impulsive and hyperactive behavior. Tricyclic antidepressants have well-demonstrated efficacy in treating behavioral symptoms, but desipramine should be avoided, at least in youths and adolescents (and perhaps adults), because safer tricyclics are available. Bupropion was effective in its few controlled trials, but tics and (especially in youth) skin rash limit its value. Venlafaxine appears effective, but controlled studies are needed. Serotonin selective reuptake inhibitors have not been tested in controlled trials, but they cause inconsistent changes, often aggravate ADHD symptoms, and can cause frontal apathy and disinhibition. Clonidine has not been adequately examined but seems to have small or uncertain effects. Psychostimulants remain the treatment of choice because of their unique effect on attention. Multimodal treatments (medications plus psychosocial) might not be more effective than medications alone. PMID:9418743

  19. Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Johnston, Kate; Madden, Anya K.; Bramham, Jessica; Russell, Ailsa J.

    2011-01-01

    Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are hypothesised to involve core deficits in executive function. Previous studies have found evidence of a double dissociation between the disorders on specific executive functions (planning and response inhibition). To date most research has been conducted with…

  20. Altered salience processing in attention deficit hyperactivity disorder.

    Science.gov (United States)

    Tegelbeckers, Jana; Bunzeck, Nico; Duzel, Emrah; Bonath, Björn; Flechtner, Hans-Henning; Krauel, Kerstin

    2015-06-01

    Attentional problems in patients with attention deficit hyperactivity disorder (ADHD) have often been linked with deficits in cognitive control. Whether these deficits are associated with increased sensitivity to external salient stimuli remains unclear. To address this issue, we acquired functional brain images (fMRI) in 38 boys with and without ADHD (age: 11-16 years). To differentiate the effects of item novelty, contextual rareness and task relevance, participants performed a visual oddball task including four stimulus categories: a frequent standard picture (62.5%), unique novel pictures (12.5%), one repeated rare picture (12.5%), and a target picture (12.5%) that required a specific motor response. As a main finding, we can show considerable overlap in novelty-related BOLD responses between both groups, but only healthy participants showed neural deactivation in temporal as well as frontal regions in response to novel pictures. Furthermore, only ADHD patients, but not healthy controls, engaged wide parts of the novelty network when processing the rare but familiar picture. Our results provide first evidence that ADHD patients show enhanced neural activity in response to novel but behaviorally irrelevant stimuli as well as reduced habituation to familiar items. These findings suggest an inefficient use of neuronal resources in children with ADHD that could be closely linked to increased distractibility. PMID:25648705

  1. Executive Function in Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Sinha, Preeti; Sagar, Rajesh; Mehta, Manju

    2008-01-01

    Aim: To assess executive functions in medication naive children with attention deficit/hyperactivity (ADHD). Method: Group matched (age and gender) children with ADHD (N=30) and healthy children (N=30) in the age range of 6-14 years were compared on measures of executive functions (response inhibition, working memory, cognitive flexibility,…

  2. Methylphenidate use in children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Felipe Salles Neves Machado

    2015-01-01

    Full Text Available A Brazilian Health Technology Assessment Bulletin (BRATS article regarding scientific evidence of the efficacy and safety of methylphenidate for treating attention deficit hyperactivity disorder (ADHD has caused much controversy about its methods. Considering the relevance of BRATS for public health in Brazil, we critically reviewed this article by remaking the BRATS search and discussing its methods and results. Two questions were answered: did BRATS include all references available in the literature? Do the conclusions reflect the reviewed articles? The results indicate that BRATS did not include all the references from the literature on this subject and also that the proposed conclusions are different from the results of the articles chosen by the BRATS authors themselves. The articles selected by the BRATS authors showed that using methylphenidate is safe and effective. However, the BRATS final conclusion does not reflect the aforementioned and should not be used to support decisions on the use of methylphenidate.

  3. Psychosocial treatments for children with attention deficit/hyperactivity disorder.

    Science.gov (United States)

    Daly, Brian P; Creed, Torrey; Xanthopoulos, Melissa; Brown, Ronald T

    2007-03-01

    This article reviews studies examining the efficacy of behavioral interventions for the treatment of attention-deficit/hyperactivity disorder (ADHD). A specific emphasis is placed on evidence-based interventions that include parent training, classroom, academic, and peer interventions. Results indicate that school-aged children respond to behavioral interventions when they are appropriately implemented both at home and in the classroom setting. Combined treatments (behavioral management and stimulant medication) represent the gold standard in ADHD treatment and are often recommended as the first-line treatment option due to the many problems faced by children with ADHD. Diversity issues, although an important consideration in the treatment of ADHD, continue to remain an understudied area. Recommendations for future research are made pertaining to treatment sequencing with regard to behavior management as well as for subgroups of ADHD children who may respond best to specific treatments. PMID:17260167

  4. ATTENTION DEFICIT HYPERACTIVITY DISORDER: COMORBIDITIES, EMPHASIS ON CONCURRENCE WITH EPILEPSY

    Directory of Open Access Journals (Sweden)

    O. A. Pylaeva

    2015-06-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is the most common cause of behavioral disorders and learning problems at preschool and school ages. Patients with ADHD are frequently found to have comorbidities that present additional diagnostic and therapeutic problems and result in an even greater decrease in quality of life in patients. Thus, ADHD is frequently concurrent with epilepsy; in this case, not only the manifestations of ADHD are more common in epilepsy, but the latter is more often encountered in patients with ADHD than in those as a whole. The authors consider the epidemiological factors and causes, which may lead to a concurrence of these two diseases in the same patient, the principles of diagnosis and differential diagnosis of ADHD in epileptic patients, the specific features of treatment in this patient category. At the same time, the authors place emphasis on the fact that some antiepileptic drugs, such as barbiturates, may cause symptoms that mimic ADHD (in these cases, inattention and hyperactivity are adverse reactions of therapy and lessen or disappear after drug discontinuation or enhance the manifestations of ADHD in patients with a concurrence of these two diseases. On the other hand, care should be also taken to choose drugs for the treatment of ADHD due to the possible higher frequency of seizures. So preference should be given to the drugs having no negative effect on the course of comorbidities or those having a positive therapeutic effect against both diseases. 

  5. The search for biomarkers for attention deficit/hyperactivity disorder.

    Science.gov (United States)

    Wallis, Deeann

    2010-09-01

    The main characteristic of attention deficit/hyperactivity disorder (ADHD) is a persistent pattern of inattention and/or hyperactivity-impulsivity which is more frequent and severe than is usually expected in individuals at a comparable level of development. ADHD is estimated to affect approximately 5.29% of school-aged children and is therefore the most common childhood onset psychological disorder. A conservative estimate of the annual societal cost of illness for ADHD in childhood and adolescence is USD 42.5 billion in the U.S. alone. Global sales of ADHD medicines could reach USD 4.3 billion by 2012. Despite the prevalence, high heritability and costs of ADHD, biological markers do not exist. Such biomarkers are in high demand as they would help eliminate the subjective diagnoses based on interviews and potentially allow for earlier diagnosis and personalized medicine. Lack of markers likely stems from several factors that complicate ADHD research and the assessment of pharmacological responses. This review analyses complicating factors in defining ADHD phenotype and etiology, identifying specific diagnostic markers and the difficulties in the assessment of pharmacogenomic markers. The dopamine transporter (DAT1) genotype and methylphenidate (MPH) response are detailed as an example of a biomarker. A recent report of a novel ADHD gene and its possible role as a biomarker is explored. Finally, suggestions for strategies and study designs for future research for the definition of effective ADHD biomarkers are made. PMID:20862396

  6. Addressing attention-deficit/hyperactivity disorder in the workplace.

    Science.gov (United States)

    Sarkis, Elias

    2014-09-01

    Although generally considered a childhood disorder, attention-deficit/hyperactivity disorder (ADHD) can persist into adulthood and impede achievement in the workplace. Core ADHD symptoms of inattention, hyperactivity, and impulsivity can be associated with poor organization, time management, and interpersonal relationships. Employment levels, earning power, and productivity are reduced among individuals with ADHD compared with those without ADHD. Furthermore, the costs of employing individuals with ADHD are higher because of work absences and lost productivity. The primary care provider plays an integral role in managing ADHD symptoms and providing the necessary resources that will help individuals with ADHD succeed in the workplace. Pharmacotherapy can reduce ADHD symptoms and improve functioning; however, it is also important to consider how positive traits associated with ADHD, such as creative thinking, can be used in the workplace. Workplace accommodations and behavioral therapies, such as coaching, can also enhance time management and organizational skills. This review describes how ADHD symptoms affect workplace behaviors, the effect of ADHD on employment and workplace performance, and the management of ADHD in working adults. PMID:25295647

  7. Cognitive Remediation Strategies : An Adjunct to the Psychotherapy of Adults With Attention-Deficit Hyperactivity Disorder

    OpenAIRE

    WEINSTEIN, CHERYL S.

    1994-01-01

    Evidence continues to emerge that childhood symptoms of attention-deficit hyperactivity disorder (ADHD) persist into adulthood. These symptoms include motoric hyperactivity, restlessness, attention deficits, poor organizational skills, impulsivity, and memory impairment. Poor academic and work performance, frustration, humiliation, and shame are also components of adult ADHD. Psychotherapists are challenged to understand the meaning of the disorder and its ramifications in a...

  8. A Meta-Analysis of Behavioral Parent Training for Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Lee, Pei-chin; Niew, Wern-ing; Yang, Hao-jan; Chen, Vincent Chin-hung; Lin, Keh-chung

    2012-01-01

    This meta-analysis examined the effect of behavioral parent training on child and parental outcomes for children with attention deficit hyperactivity disorder. Meta-analytic procedures were used to estimate the effect of behavioral parent training on children with attention deficit hyperactivity disorder. Variables moderating the intervention…

  9. Developmental Changes in Attention and Comprehension among Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Bailey, Ursula L.; Lorch, Elizabeth P.; Milich, Richard; Charnigo, Richard

    2009-01-01

    Changes in visual attention and story comprehension for children (N = 132) with attention deficit hyperactivity disorder (ADHD) and comparison peers were examined. Between the ages of 7 and 9 (Phase 1) and approximately 21 months later (Phase 2), children viewed 2 televised stories: 1 in the presence of toys and 1 in their absence. Both groups of…

  10. Differential Effects of Methylphenidate on Attentional Functions in Children with Attention-Deficit-Hyperactivity Disorder

    Science.gov (United States)

    Konrad, Kerstin; Gunther, Thomas; Hanisch, Charlotte; Herpertz-Dahlmann, Beate

    2004-01-01

    Objective: To examine the effects of methylphenidate on different attentional functions and behavior in children with attention-deficit-hyperactivity disorder (ADHD). Method: A total of 60 ADHD children aged between 8 and 12 years completed a randomized, double-blind, placebo-controlled, within-subject crossover trial with two doses of…

  11. Investigation of Prevalence of Attention Deficit Hyperactivity Disorder among Adolescents

    Directory of Open Access Journals (Sweden)

    Zuhal Uyan1

    2014-09-01

    Full Text Available Aim: Attention deficit hyperactivity disorder (ADHD is the most common neurobehavioral disorder of childhood and adolescence. The aim of this study is to investigate the prevalence of ADHD with oppositional defiant disorder (ODD and conduct disorder (CD which may accompany to ADHD according to parent and teacher statements. Method: This cross-sectional research involving 251 adolescents from 9 different schools in Ankara was carried out between April and June 2007. Adolescents were assessed in Child and Adolescent Behavior Disorders Screening and Rating Scale based on DSM-IV. A questionnaire was used for sociodemographic attributes. Screening and rating scale was completed by both class teacher and parent of the students. Results: According to the combined statements of parent and teacher 5.9% of the students had ADHD symptoms. The prevalence of ADHD was 12.7% and 27.4% on the basis of parent and teacher reports respectively. ADHD symptoms were significantly higher among boys on the basis of both teacher and parent reports (p<0.001. There was no significant difference between ADHD symptoms and socioeconomic status and parent education level. The prevalence of ODD was 46.4% and 52.5% among adolescents with ADHD symptoms according to parent and teacher assessments respectively. Conclusion: Informing parent and teachers about DEHB and other disruptive behaviors, and about the outcomes due these problems is important in view of early recognition of the problem, initiation of treatment and being supportive for the adolescent.

  12. Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development

    OpenAIRE

    Corbett, Blythe A.; Constantine, Laura J.; Hendren, Robert; Rocke, David; Ozonoff, Sally

    2009-01-01

    Executive functioning (EF) is an overarching term that refers to neuropsychological processes that enable physical, cognitive, and emotional self-control. Deficits in EF are often present in neurodevelopmental disorders, but the specificity of EF deficits and direct comparison across disorders is rare. The current study investigated EF in 7 to 12 year old children with autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD) and typical development using a comprehensive...

  13. Emotion perception in adult attention-deficit hyperactivity disorder.

    Science.gov (United States)

    Bisch, Jeanne; Kreifelts, Benjamin; Bretscher, Johannes; Wildgruber, Dirk; Fallgatter, Andreas; Ethofer, Thomas

    2016-08-01

    This study examined identification of emotional information in facial expression, prosody, and their combination in 23 adult patients with combined attention deficit-hyperactivity disorder (ADHD) versus 31 healthy controls (HC) matched for gender, age, and education. We employed a stimulus set which was carefully balanced for valence as well as recognizability of the expressed emotions as determined in an independent sample of HC to avoid potential biases due to different levels of task difficulty. ADHD patients were characterized by impaired recognition of all employed categories (neutral, happiness, eroticism, disgust, anger). Basic cognitive functions as assessed by neuropsychological testing, such as sustained attention, constancy of alertness, and verbal intelligence partially explained lower recognition rates. Removal of the correlated variance by means of regression analyses did not abolish lower performance in ADHD indicating deficits in social cognition independent of these neuropsychological factors (p recognition accuracy during bimodal presentation (p < 0.05) as compared to HC. These behavioral results can serve as foundation for future neuroimaging studies and point rather towards sensory-specific regions than audiovisual integration areas in perception of emotional information in adult ADHD. PMID:26850439

  14. Treatment for Co-Occurring Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder

    OpenAIRE

    Davis, Naomi Ornstein; Kollins, Scott H.

    2012-01-01

    Interest in the co-occurrence of attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) has grown in the last decade. Research on clinical populations supports the frequent co-occurrence of ADHD traits (e.g., hyperactivity) in individuals with ASD and ASD traits (e.g., social communication deficits) in individuals with ADHD. Similar trends in co-occurring traits have been observed in population-based samples, as well as family and genetic studies of affected indivi...

  15. Mindfulness Meditation Improves Mood, Quality of Life, and Attention in Adults with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Viviane Freire Bueno; Elisa H. Kozasa; Maria Aparecida da Silva; Tânia Maria Alves; Mario Rodrigues Louzã; Sabine Pompéia

    2015-01-01

    Objective. Adults with attention deficit hyperactivity disorder (ADHD) display affective problems and impaired attention. Mood in ADHD can be improved by mindful awareness practices (MAP), but results are mixed regarding the enhancement of attentional performance. Here we evaluated MAP-induced changes in quality of life (QoL), mood, and attention in adult ADHD patients and controls using more measures of attention than prior studies. Methods. Twenty-one ADHD patients and 8 healthy controls un...

  16. [Formal genetic findings in attention-deficit/hyperactivity-disorder].

    Science.gov (United States)

    Smidt, J; Heiser, P; Dempfle, A; Konrad, K; Hemminger, U; Kathöfer, A; Halbach, A; Strub, J; Grabarkiewicz, J; Kiefl, H; Linder, M; Knölker, U; Warnke, A; Remschmidt, H; Herpertz-Dahlmann, B; Hebebrand, J

    2003-07-01

    Twin, family and adoption studies have led to a solid understanding of the contribution of both genetic and environmental factors to the development of attention deficit/hyperactivity disorder (ADHD). We review recent studies under consideration of both methodological aspects and relevant findings. Heritability estimates in the range of 0.6 - 0.8 surpass those for most other child and adolescent psychiatric disorders. First degree relatives have elevated rates for ADHD, affective disorders, conduct disorders and substance abuse and dependency. The ADHD subtype of the index patient does not predict the subtype of other family members affected with ADHD; hence non-genetic factors seemingly account for this intrafamilial variability. Because the familial rates for ADHD are not higher in families of female in comparison to male index patients, there is no indication that the genetic loading is higher in affected females. Recently, rater effects have been discussed broadly: Whereas the heritability estimates are uniformly high independent of the informant (mother, father, teacher), the correlations between quantitatively rated symptoms are low between different informants. Knowledge of the formal genetic aspects of ADHD is a prerequisite for understanding the results of recent molecular genetic studies. PMID:12858257

  17. Overview of attention deficit hyperactivity disorder in young children

    Directory of Open Access Journals (Sweden)

    Ajay Singh

    2015-09-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is a complex disorder, which can be seen as a disorder of life time, developing in preschool years and manifesting symptoms (full and/or partial throughout the adulthood; therefore, it is not surprising that there are no simple solutions. The aim of this paper is to provide a short and concise review which can be used to inform affected children and adults; family members of affected children and adults, and other medical, paramedical, non-medical, and educational professionals about the disorder. This paper has also tried to look into the process of how ADHD develops; what are the associated problems; and how many other children and adults are affected by such problems all over the world basically to understand ADHD more precisely in order to develop a better medical and or non-medical multimodal intervention plan. If pre-school teachers and clinicians are aware of what the research tells us about ADHD, the varying theories of its cause, and which areas need further research, the knowledge will assist them in supporting the families of children with ADHD. By including information in this review about the connection between biological behavior, it is hoped that preschool teachers and clinicians at all levels will feel more confident about explaining to parents of ADHD children, and older ADHD children themselves about the probable causes of ADHD.

  18. Attentional Lapses of Adults with Attention Deficit Hyperactivity Disorder in Tasks of Sustained Attention.

    Science.gov (United States)

    Gmehlin, Dennis; Fuermaier, Anselm B M; Walther, Stephan; Tucha, Lara; Koerts, Janneke; Lange, Klaus W; Tucha, Oliver; Weisbrod, Matthias; Aschenbrenner, Steffen

    2016-06-01

    Adults with attention deficit hyperactivity disorder (ADHD) show attentional dysfunction such as distractibility and mind-wandering, especially in lengthy tasks. However, fundamentals of dysfunction are ambiguous and relationships of neuropsychological test parameters with self-report measures of ADHD symptoms are marginal. We hypothesize that basic deficits in sustaining attention explain more complex attentional dysfunction in persons with ADHD and relate to ADHD symptoms. Attentional function was analyzed by computing ex-Gaussian parameters for 3 time Blocks in a 20 min test of sustained alertness. Changes in performance across these blocks were analyzed by comparing adult persons with ADHD (n = 24) with healthy matched controls (n = 24) and correlated with neuropsychological measures of selective and divided attention as well as self-report measures of ADHD symptoms. We found a significantly steeper increase in the number of slow responses (ex-Gaussian parameter τ) in persons with ADHD with time on task in basic sustained alertness. They also performed significantly worse in tasks of sustained selective and divided attention. However, after controlling for an increase in τ during the alertness task, significant differences between groups disappeared for divided and partly selective attention. Increases in τ in the sustained alertness task correlated significantly with self-report measures of ADHD symptoms. Our results provide evidence that very basic deficits in sustaining attention in adults with ADHD are related to infrequent slow responses (=attentional lapses), with changes over time being relevant for more complex attentional function and experienced ADHD symptoms in everyday life. PMID:27193369

  19. How Can Comorbidity with Attention-Deficit/Hyperactivity Disorder Aid Understanding of Language and Speech Disorders?

    Science.gov (United States)

    Tomblin, J. Bruce; Mueller, Kathyrn L.

    2012-01-01

    This article provides a background for the topic of comorbidity of attention-deficit/hyperactivity disorder and spoken and written language and speech disorders that extends through this issue of "Topics in Language Disorders." Comorbidity is common within developmental disorders and may be explained by many possible reasons. Some of these can be…

  20. Initial Orientation of Attention towards Emotional Faces in Children with Attention Deficit Hyperactivity Disorder

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    Mehrnoosh Ahmadi

    2011-09-01

    Full Text Available Objective: Early recognition of negative emotions is considered to be of vital importance. It seems that children with attention deficit hyperactivity disorder have some difficulties recognizing facial emotional expressions, especially negative ones. This study investigated the preference of children with attention deficit hyperactivity disorder for negative (angry, sad facial expressions compared to normal children.Method: Participants were 35 drug naive boys with ADHD, aged between 6-11 years ,and 31 matched healthy children. Visual orientation data were recorded while participants viewed face pairs (negative-neutral pairs shown for 3000ms. The number of first fixations made to each expression was considered as an index of initial orientation. Results: Group comparisons revealed no difference between attention deficit hyperactivity disorder group and their matched healthy counterparts in initial orientation of attention. A tendency towards negative emotions was found within the normal group, while no difference was observed between initial allocation of attention toward negative and neutral expressions in children with ADHD .Conclusion: Children with attention deficit hyperactivity disorder do not have significant preference for negative facial expressions. In contrast, normal children have a significant preference for negative facial emotions rather than neutral faces.

  1. Complex prospective memory in adults with attention deficit hyperactivity disorder.

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    Anselm B M Fuermaier

    Full Text Available OBJECTIVES: Attention deficit hyperactivity disorder (ADHD in adults has been associated with disturbances of attention and executive functions. Furthermore, impairments of verbal and figural retrospective memory were reported. However, little is known about the effects of ADHD on prospective memory, the execution of delayed intentions in the future. METHODS: The present study compared the performance of 45 adult patients with ADHD not treated with stimulant medication with the performance of 45 matched healthy individuals on a paradigm of complex prospective memory which measured task planning, plan recall, self-initiation and execution. Furthermore, the contribution of other cognitive functions to prospective memory functioning was assessed, including measures of attention, executive functions and memory. RESULTS: A large-scale impairment could be observed in task planning abilities in patients with ADHD. Only negligible to small effects were found for plan recall, self-initiation and execution. Inhibition was identified to contribute significantly to performance on task planning. CONCLUSIONS: The present findings suggest that four cognitive components contribute to the performance of prospective memory. Impairments of prospective memory mainly emerged from deficient planning abilities in adults with ADHD. Implications on behavioral based intervention strategies are discussed.

  2. Adult attention-deficit hyperactivity disorder: key conceptual issues.

    Science.gov (United States)

    Asherson, Philip; Buitelaar, Jan; Faraone, Stephen V; Rohde, Luis A

    2016-06-01

    For many years, attention-deficit hyperactivity disorder (ADHD) was thought to be a childhood-onset disorder that has a limited effect on adult psychopathology. However, the symptoms and impairments that define ADHD often affect the adult population, with similar responses to drugs such as methylphenidate, dexamphetamine, and atomoxetine, and psychosocial interventions, to those seen in children and adolescents. As a result, awareness of ADHD in adults has rapidly increased and new clinical practice has emerged across the world. Despite this progress, treatment of adult ADHD in Europe and many other regions of the world is not yet common practice, and diagnostic services are often unavailable or restricted to a few specialist centres. This situation is remarkable given the strong evidence base for safe and effective treatments. Here we address some of the key conceptual issues surrounding the diagnosis of ADHD relevant to practising health-care professionals working with adult populations. We conclude that ADHD should be recognised in the same way as other common adult mental health disorders, and that failure to recognise and treat ADHD is detrimental to the wellbeing of many patients seeking help for common mental health problems. PMID:27183901

  3. Adult attention deficit hyperactivity disorder is associated with asthma

    Directory of Open Access Journals (Sweden)

    Halmøy Anne

    2011-08-01

    Full Text Available Abstract Background Attention deficit hyperactivity disorder (ADHD is increasingly recognized as a common disorder not only in children, but also in the adult population. Similarly, asthma also has a substantial prevalence among adults. Previous studies concerning a potential relationship between ADHD and asthma have not presented consistent results. Methods A cross-sectional study of 594 adult patients diagnosed with ADHD, compared with 719 persons from the general population. Information was collected between 1997 and 2005 using auto-questionnaires rating past and present symptoms of ADHD, co-morbid conditions, including asthma, and work status. Results The prevalence of asthma was significantly higher in the ADHD patient group compared to the controls, 24.4% vs. 11.3% respectively (OR = 2.54, 95% CI 1.89-3.44, and controls with asthma scored higher on ratings of both past and present symptoms of ADHD. Female ADHD patients had a significantly higher prevalence of asthma compared to male ADHD patients (30.9% vs. 18.2%, OR = 2.01, CI 1.36-2.95, but in controls a slight female preponderance was not statistically significant. In both ADHD patients and controls, having asthma was associated with an increased prevalence of symptoms of mood- and anxiety disorders. Conclusions The present findings point to a co-morbidity of ADHD and asthma, and these patients may represent a clinical and biological subgroup of adult patients with ADHD.

  4. Motor development of children with attention deficit hyperactivity disorder

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    Francisco Rosa Neto

    2015-09-01

    Full Text Available Objective:To compare both global and specific domains of motor development of children with attention deficit hyperactivity disorder (ADHD with that of typically developing children.Methods:Two hundred children (50 children with clinical diagnoses of ADHD, according to the DSM-IV-TR and 150 typically developing controls, aged 5 to 10 years, participated in this cross-sectional study. The Motor Development Scale was used to assess fine and global motricity, balance, body schema, and spatial and temporal organization.Results:Between-group testing revealed statistically significant differences between the ADHD and control groups for all domains. The results also revealed a deficit of nearly two years in the motor development of children with ADHD compared with the normative sample.Conclusion:The current study shows that ADHD is associated with a delay in motor development when compared to typically developing children. The results also suggested difficulties in certain motor areas for those with ADHD. These results may point to plausible mechanisms underlying the relationship between ADHD and motor difficulties.

  5. Source discrimination in adults with attention deficit hyperactivity disorder.

    Directory of Open Access Journals (Sweden)

    Anselm B M Fuermaier

    Full Text Available OBJECTIVES: The context of memory experiences is referred to as source memory and can be distinguished from the content of episodic item memory. Source memory represents a crucial part of biographic events and elaborate memory experiences. Whereas individuals with attention deficit hyperactivity disorder (ADHD were shown to have inefficient item memory, little is known about the context of memory experiences. METHODS: The present study compared 37 adult patients with a diagnosed ADHD with 40 matched healthy participants on a word list paradigm. Memory functions of encoding, retention and source discrimination were assessed. Furthermore, standardized measures of memory and executive control were applied in order to explore a qualitative differentiation of memory components. RESULTS: Adult patients with ADHD showed impaired performance in encoding of new information whereas the retention of encoded items was found to be preserved. The most pronounced impairment of patients with ADHD was observed in source discrimination. Regression models of cognitive functions on memory components supported some qualitative differentiation. CONCLUSIONS: Data analysis suggests a differential pattern of memory impairment in adults suffering from ADHD with a particular deficit in source discrimination. Inefficient source discrimination in adults with ADHD can affect daily functioning by limiting biographic awareness and disturbing general cognitive processes.

  6. Attention Deficit Hyperactivity Disorder in the Light of the Epigenetic Paradigm

    OpenAIRE

    Schuch, Viviane; Utsumi, Daniel Augusto; Costa, Thaís Virgínia Moura Machado; Kulikowski, Leslie Domenici; Muszkat, Mauro

    2015-01-01

    Attention deficit hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder characterized by a definite behavioral pattern that might lead to performance problems in the social, educational, or work environments. In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, the symptoms of ADHD were restricted to those associated with cognitive (attention deficit) and behavioral (hyperactivity/impulsivity) deficits, while deficient emotional self-regulatio...

  7. Sleep Restores Daytime Deficits in Procedural Memory in Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Prehn-Kristensen, Alexander; Molzow, Ina; Munz, Manuel; Wilhelm, Ines; Muller, Kathrin; Freytag, Damaris; Wiesner, Christian D.; Baving, Lioba

    2011-01-01

    Sleep supports the consolidation of declarative and procedural memory. While prefrontal cortex (PFC) activity supports the consolidation of declarative memory during sleep, opposite effects of PFC activity are reported with respect to the consolidation of procedural memory during sleep. Patients with attention-deficit/hyperactivity disorder (ADHD)…

  8. Cortisol Response to Stress in Adults with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Corominas-Roso, Margarida; Palomar, Gloria; Ferrer, Roser; Real, Alberto; Nogueira, Mariana; Corrales, Montserrat; Casas, Miguel; Ramos-Quiroga, Josep Antoni

    2015-01-01

    Background: Differences in the cortisol response have been reported between children exhibiting the inattentive and hyperactive/impulsive subtypes of attention deficit hyperactivity disorder. However, there is no such information about adults. The aim of the present study was to determine the possible differences between the combined and inattentive subtypes in the cortisol response to stress. Methods: Ninety-six adults with attention deficit hyperactivity disorder, 38 inattentive and 58 comb...

  9. High dose methylphenidate treatment in adult Attention Deficit Hyperactivity Disorder: a case report

    OpenAIRE

    Liebrenz Michael; Hof Danielle; Buadze Anna; Stohler Rudolf; Eich Dominique

    2012-01-01

    Abstract Introduction Stimulant medication improves hyperactivity, inattention, and impulsivity in both pediatric and adult populations with Attention Deficit Hyperactivity Disorder (ADHD). However, data regarding the optimal dosage in adults is still limited. Case presentation We report the case of a 38-year-old Caucasian patient who was diagnosed with Attention Deficit Hyperactivity Disorder when he was nine years old. He then received up to 10 mg methylphenidate (Ritalin®) and 20 mg sustai...

  10. Attention Deficit/Hyperactivity Disorder in Adults with Sleep Apnea

    OpenAIRE

    Oğuztürk, Ömer; Ekici, Mehmet; Çimen, Dilay; Ekici, Aydanur; Senturk, Erol

    2012-01-01

    AAttention deficit hyperactivity disorder (ADHD) is a common childhood illness. In some patients, this illness may persist into adulthood and an association between ADHD and Obstructive Sleep Apnea (OSA) has been found in childhood. However, it is unclear how OSA and ADHD coincide in adulthood. Therefore, to explore the relationship between OSA and adult ADHD the current investigation utilized a clinically-based cross-sectional survey. Subjects consisted of 81 treatment-naïve OSA patients and...

  11. Assessment of Working Memory in Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Messina, Lucinete de Freitas; Tiedemann, Klaus Bruno; de Andrade, Enio Roberto; Primi, Ricardo

    2006-01-01

    Objective: This research investigated the cognitive abilities and the working memory in children and youngsters with three different types of attention-deficit/hyperactivity disorder (ADHD): (a) mainly with attention-deficit, (b) hyperactive and impulsive, and (c) combined. Method: A computerized test called Infant Cognitive Abilities Test, which…

  12. Attention-deficit/hyperactivity disorder in postsecondary students

    Directory of Open Access Journals (Sweden)

    Nugent K

    2014-09-01

    Full Text Available Kevin Nugent,1 Wallace Smart2,3 1Kinark Child and Family Services, Trent University and Sir Sanford Fleming College, Peterborough, ON, Canada; 2Department of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; 3University of Lethbridge Health Centre, Lethbridge, AB, Canada Abstract: A PubMed review was conducted for papers reporting on attention-deficit/ hyperactivity disorder (ADHD in postsecondary students. The review was performed in order to determine the prevalence and symptomatology of ADHD in postsecondary students, to examine its effects on academic achievement, and discuss appropriate management. The prevalence of ADHD symptoms among postsecondary students ranges from 2% to 12%. Students with ADHD have lower grade point averages and are more likely to withdraw from courses, to indulge in risky behaviors, and to have other psychiatric comorbidities than their non-ADHD peers. Ensuring that students with ADHD receive appropriate support requires documented evidence of impairment to academic and day-to-day functioning. In adults with ADHD, stimulants improve concentration and attention, although improved academic productivity remains to be demonstrated. ADHD negatively impacts academic performance in students and increases the likelihood of drug and alcohol problems. Affected students may therefore benefit from disability support services, academic accommodations, and pharmacological treatment. Keywords: adults, academic performance, stimulants, treatment

  13. Advances and Considerations in Attention-Deficit/Hyperactivity Disorder Pharmacotherapy

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    Shahin Akhondzadeh

    2011-08-01

    Full Text Available Attention-deficit/hyperactivity disorder (ADHD is a highly heritable neuropsychiatric disorder associated with significant impairments in occu¬pational, academic, neuropsychological, and social functioning. Central nervous system (CNS stimulants are recommended as first-line medication therapy for children. CNS stimulants include formulations of methylphenidate and amphetamine derivatives and are available in a large variety of immediate- and extended-release preparations. Extended-release preparations are often preferred to limit drug administration during school or work and may help to limit side effects associated with rapid fluctuations in serum concentration. Stimulant medication is by far the most commonly used treatment in managing children with ADHD, 10-20% of those who take such medication do now show clinically significant improvements in their primary ADHD symptom. Even when a favorable response is obtained, some children experience side effects that are of sufficient occurrence and severity to prevent continued use of stimulant medication. In such instances or when families are unwilling to consider a stimulant, non-stimulant medications may be appealing. This review focuses on etiology, assessment and treatment of ADHD with various stimulant and non-stimulant agents.

  14. Advances and considerations in attention-deficit/hyperactivity disorder pharmacotherapy.

    Science.gov (United States)

    Mohammadi, Mohammad; Akhondzadeh, Shahin

    2011-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric disorder associated with significant impairments in occupational, academic, neuropsychological, and social functioning. Central nervous system (CNS) stimulants are recommended as first-line medication therapy for children. CNS stimulants include formulations of methylphenidate and amphetamine derivatives and are available in a large variety of immediate- and extended-release preparations. Extended-release preparations are often preferred to limit drug administration during school or work and may help to limit side effects associated with rapid fluctuations in serum concentration. Stimulant medication is by far the most commonly used treatment in managing children with ADHD, 10-20% of those who take such medication do now show clinically significant improvements in their primary ADHD symptom. Even when a favorable response is obtained, some children experience side effects that are of sufficient occurrence and severity to prevent continued use of stimulant medication. In such instances or when families are unwilling to consider a stimulant, non-stimulant medications may be appealing. This review focuses on etiology, assessment and treatment of ADHD with various stimulant and non-stimulant agents. PMID:22009816

  15. Neuroscience of attention deficit hyperactivity disorder (ADHD- a review

    Directory of Open Access Journals (Sweden)

    Haile D.B

    2013-05-01

    Full Text Available Attention Deficit Hyperactivity disorder (ADHD does not have a single underlying pathophysiology which seems it has a multifaceted etiology. There are various contributing factors for ADHD, environmental and genetic being few of them. This neurobiological disorder has been a result of continuous actions of the risk factors. Neuroimaging study has indicated that children suffering from ADHD had immature brains compared to other children. This has pointed towards the fact that the Cerebellum, Basal Ganglia and the Prefrontal cortex parts of the brain are predominantly affected. The pharmacological & neuroimaging studies implicated that the dysregulation of the neuronal pathways of the Neurotransmitters (Dopamine and Norepinephrine being primarily responsible for ADHD. The principal treatment procedure involves Pharmacotherapy (Medication and other effective Psychotherapy (Psychopharmacological methods for ADHD. Presently immediate release Methylphenidate (Ritalin, Coencerta has been clinically approved for the diagnosis of ADHD. The psychotherapy evolves self-consciousness of sensory and cognitive thinking strengths and blind spots deliver some respite and enhanced enactment. The pharmacotherapy should strategize complete treatment plan including behavioural and educational aspects.

  16. Risperidone Treatment in 12 Children With Developmental Disorders and Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Eapen, Valsamma; Gururaj, A K

    2005-01-01

    Background: Risperidone is a novel antipsychotic drug that has been tried in the treatment of several child psychiatric disorders. In an open clinical study, we evaluated the safety and efficacy of risperidone in children with developmental disorder and behavioral problems including attention-deficit/hyperactivity disorder (ADHD).

  17. Schizophrenia Spectrum and Attention-Deficit/Hyperactivity Disorder Symptoms in Autism Spectrum Disorder and Controls

    Science.gov (United States)

    Gadow, Kenneth D.

    2012-01-01

    Objective: This study compared the differential severity of specific symptoms of schizophrenia spectrum disorder (SSD) in children with autism spectrum disorder (ASD) and child psychiatry outpatient referrals (controls). Each group was further subdivided into subgroups with and without co-occurring attention-deficit/hyperactivity disorder (ADHD).…

  18. Attention Deficit Hyperactivity Disorder Erroneously Diagnosed and Treated as Bipolar Disorder

    Science.gov (United States)

    Atmaca, Murad; Ozler, Sinan; Topuz, Mehtap; Goldstein, Sam

    2009-01-01

    Objective: There is a dearth of literature on patients erroneously diagnosed and treated for bipolar disorder. Method: The authors report a case of an adult with attention deficit hyperactivity disorder erroneously diagnosed and treated for bipolar disorder for 6 years. At that point, methylphenidate was initiated. The patient was judged to be a…

  19. Test of Alternative Hypotheses Explaining the Comorbidity between Attention-Deficit/Hyperactivity Disorder and Conduct Disorder

    Science.gov (United States)

    Rhee, Soo Hyun; Willcutt, Erik G.; Hartman, Christie A.; Pennington, Bruce F.; DeFries, John C.

    2008-01-01

    There is significant comorbidity between attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD). The conclusions of studies that examined the causes of comorbidity between ADHD and CD conflict, with some researchers finding support for the three independent disorders model and others finding support for the correlated risk…

  20. Predicting Attention-Deficit/Hyperactivity Disorder and Oppositional Defiant Disorder from Preschool Diagnostic Assessments

    Science.gov (United States)

    Harvey, Elizabeth A.; Youngwirth, Sara D.; Thakar, Dhara A.; Errazuriz, Paula A.

    2009-01-01

    The present study examined the power of measures of early preschool behavior to predict later diagnoses of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD)/conduct disorder (CD). Participants were 168 children with behavior problems at age 3 who underwent a multimethod assessment of ADHD and ODD symptoms and…

  1. Bipolar Disorder Comorbid With Attention-Deficit/Hyperactivity Disorder in Adult Inpatients With Acute Relapse

    OpenAIRE

    Marin, Alina; Scott, Duncan; Groll, Dianne L

    2013-01-01

    Objective: The aim of this prospective, observational study was to detect the rate of comorbid attention-deficit/hyperactivity disorder (ADHD) in a sample of inpatients diagnosed with bipolar disorder, and to identify differences between patients with bipolar disorder with concomitant ADHD and those without concomitant ADHD.

  2. A Comparative Study on the Visual Perceptions of Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Ahmetoglu, Emine; Aral, Neriman; Butun Ayhan, Aynur

    This study was conducted in order to (a) compare the visual perceptions of seven-year-old children diagnosed with attention deficit hyperactivity disorder with those of normally developing children of the same age and development level and (b) determine whether the visual perceptions of children with attention deficit hyperactivity disorder vary with respect to gender, having received preschool education and parents` educational level. A total of 60 children, 30 with attention deficit hyperactivity disorder and 30 with normal development, were assigned to the study. Data about children with attention deficit hyperactivity disorder and their families was collected by using a General Information Form and the visual perception of children was examined through the Frostig Developmental Test of Visual Perception. The Mann-Whitney U-test and Kruskal-Wallis variance analysis was used to determine whether there was a difference of between the visual perceptions of children with normal development and those diagnosed with attention deficit hyperactivity disorder and to discover whether the variables of gender, preschool education and parents` educational status affected the visual perceptions of children with attention deficit hyperactivity disorder. The results showed that there was a statistically meaningful difference between the visual perceptions of the two groups and that the visual perceptions of children with attention deficit hyperactivity disorder were affected meaningfully by gender, preschool education and parents` educational status.

  3. Connectivity supporting attention in children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Anita D. Barber

    2015-01-01

    While CON–DMN anti-correlation is associated with improved attention in ADHD, other circuitry supports improved attention in TD children. Greater CON–DMN anti-correlation supported better attentional control in children with ADHD, but worse attentional control in TD children. On the other hand, greater DMN–occipital anti-correlation supported better attentional control in TD children.

  4. Use of Digital Console Game for Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Chuang, Tsung-Yen; Lee, I-Ching; Chen, Wen-Chih

    2010-01-01

    ADHD or ADD (Attention Deficit/Hyperactivity Disorder) is one of the most frequently diagnosed mental and behavioral disorders of children. Children with ADHD are characterized by poor attention and distractibility and/or hyperactive and impulsive behaviors. Although there is no "cure" for ADHD, there are accepted treatments that specifically…

  5. Dietary Patterns and Attention Deficit Hyperactivity Disorder among Iranian Children

    Directory of Open Access Journals (Sweden)

    Leila Azadbakht

    2012-04-01

    Full Text Available Background: : To evaluate the association of major dietary patterns identified by factor analysis and attention deficit hyperactivity disorder (ADHD in a group of Iranian school aged children.Materials and Method: : This cross-sectional study was conducted among 375 school-aged children in Tehran, Iran. Usual dietary intakes were assessed by a semi-quantitative food frequency questionnaire. DSM-IV questionnaire was used to determine the prevalence of ADHD. Major dietary patterns were identified by factor analysis. Results: The prevalence of ADHD was 9.7% in this population. We identified 4 major dietary patterns: "healthy", "western", "sweet" and "fast foods" dietary patterns. Children in top quintile of "sweet dietary pattern” score had greater odds for having ADHD as compared with those in the lowest quintile (Odds ratio: 3.95; 95% CI: 1.16, 15.31; p=0.03. Greater adherence to "fast food" dietary pattern was significantly associated with higher risk of having ADHD (Odds ratio: 3.21; 95% CI: 1.05, 10.90; p=0.03. No overall significant associations were seen between either healthy or western dietary patterns with ADHD. All these analysis were done in the controlled model for confounders.Conclusion: We found significant independent associations between "sweet" and "fast foods" dietary patterns and prevalence of ADHD. Prospective studies are required to confirm these findings

  6. Attention-deficit hyperactivity disorder, drug companies and the internet.

    Science.gov (United States)

    Mitchell, Jessica; Read, John

    2012-01-01

    This study investigated the influence of drug-company funding on websites about attention-deficit hyperactivity disorder (ADHD). Websites in the top 60 for either Google or Yahoo!Xtra with information about causation and treatment were analysed. Likert scales, based on those used in previous similar studies, were developed to rate aetiological explanations and recommended treatment approaches, on a dimension from psycho-social to biological. Overall, the quality of information on websites was poor with a strong bias towards bio-genetic aetiological explanations of ADHD. Twenty-one of the 57 websites (37%) were funded by drug companies. The drug-company funded (DCF) websites were significantly more likely than non-DCF websites to recommend medication rather than psycho-social treatments. The selective lack of consideration of psycho-social treatments by DCF websites is discussed in relation to the relevant research literature, including the evidence in favour of a multimodal approach. The findings, which are consistent with previous similar studies in relation to websites about adult mental health problems, confirm that the pharmaceutical industry is seeking to influence public opinion via the internet. PMID:21429977

  7. Functional MRI studies in children with attention deficit hyperactivity disorder

    International Nuclear Information System (INIS)

    Objective: To investigate the brain activation map during Go-NoGo tasks in children with attention deficit hyperactivity disorder (ADHD) and matched controls using functional MRI. Methods: Block designed BOLD functional MRI scan covering the whole brain was performed on 10 boys having ADHD and 11 healthy boys. The 2 groups were matched by age, sex, and handedness. Executing advanced inhibitory Go-NoGo tasks served as stimuli for all subjects. The fMRI data was analyzed by SPM99 (Statistical Parametric Mapping) software with statistic t-test to generate the activation map. Results: (1) The normal children showed significant activations in left thalamus and right cingulate gyrus and fewer activations in right middle frontal gyrus during stimulate controlled Go task, but the children with ADHD showed less activations in left thalamus. (2) In response controlled Go task, the normal children showed activations in right insula, cingulate gyrus and left frontal gyrus, while the ADHD children showed lower power of response in the right middle frontal gyrus.(3) In NoGo task, right middle frontal gyrus was the dominant activated regions, and left anterior cingulate, left middle frontal gyrus and right thalamus also had some activations in normal children, while the activations of right prefrontal decreased and the thalamus increased in ADHD boys. Conclusion: In children with ADHD, some dysfunctional brain areas, mainly the prefrontal lobe and anterior cingulate gyrus were found. Thalamus was also involved according to the brain activation map

  8. Understanding intentionality in children with attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Mohammadzadeh, Azar; Tehrani-Doost, Mehdi; Khorrami, Anahita; Noorian, Nahid

    2016-06-01

    One of the main aspects of theory of mind is intentionality which refers to recognizing other people's intentions in their behaviors. The aim of this study was to investigate intentionality in children with attention-deficit/hyperactivity disorder (ADHD). Thirty children with ADHD were compared to thirty age- and IQ-matched normal children. All participants were assessed using the moving shapes paradigm task which contains one large red and one small blue triangle moving around a black screen. They were asked to describe what the movements mean and how the triangles interact with each other. The answers were rated based on the accuracy, type of descriptions applied, mental states, and length of phrases. With regard to intentionality score, children with ADHD performed significantly worse than normal children (P < .05). Based on appropriateness score, the accuracy of patients' answers was lower in comparison with the control group. Children with ADHD used longer phrases as compared to controls. Children with ADHD can have problems with comprehending others' intentionality. This leads to impairment in social relationship. PMID:26613599

  9. Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach.

    Science.gov (United States)

    Mooney, Michael A; McWeeney, Shannon K; Faraone, Stephen V; Hinney, Anke; Hebebrand, Johannes; Nigg, Joel T; Wilmot, Beth

    2016-09-01

    Despite a wealth of evidence for the role of genetics in attention deficit hyperactivity disorder (ADHD), specific and definitive genetic mechanisms have not been identified. Pathway analyses, a subset of gene-set analyses, extend the knowledge gained from genome-wide association studies (GWAS) by providing functional context for genetic associations. However, there are numerous methods for association testing of gene sets and no real consensus regarding the best approach. The present study applied six pathway analysis methods to identify pathways associated with ADHD in two GWAS datasets from the Psychiatric Genomics Consortium. Methods that utilize genotypes to model pathway-level effects identified more replicable pathway associations than methods using summary statistics. In addition, pathways implicated by more than one method were significantly more likely to replicate. A number of brain-relevant pathways, such as RhoA signaling, glycosaminoglycan biosynthesis, fibroblast growth factor receptor activity, and pathways containing potassium channel genes, were nominally significant by multiple methods in both datasets. These results support previous hypotheses about the role of regulation of neurotransmitter release, neurite outgrowth and axon guidance in contributing to the ADHD phenotype and suggest the value of cross-method convergence in evaluating pathway analysis results. © 2016 Wiley Periodicals, Inc. PMID:27004716

  10. Adult Attention Deficit Hyperactivity Disorder and Parenting Styles.

    Science.gov (United States)

    Karbalaei Sabagh, Ali; Khademi, Mojgan; Noorbakhsh, Simasadat; Razjooyan, Katayoon; Arabgol, Fariba

    2016-03-01

    The aim of the present study was to compare the parenting styles in parents with and without adult attention deficit hyperactivity disorder (ADHD) who had children with ADHD. It was a case-control study with convenience sampling strategy. Participants were recruited from the parents of previously diagnosed children with ADHD referred to Imam Hossein Hospital, Tehran/ Iran. Ninety parents with adult ADHD and 120 normal parents were chosen by Conner's Adult ADHD Screening Scale (CAARS) and psychiatrist interview. Using Baumrind Parenting Styles Questionnaire and Arnold Parenting Scale, parenting styles were assessed in both the groups. Results from independent samples t-test indicated that Authoritarian parenting style (F = 0.576, p 0.022) and Over reacting style (F = 7.976, p 0.045) were significantly higher in cases. On the other hand, controls were using Permissive style (F = 0.131, p 0.044) more than cases. The results are consistent with prior studies; these findings can improve the content of parent training for children with ADHD, who have adult ADHD themselves. PMID:26264632

  11. Attention Deficit Hyperactivity Disorder (ADHD) and Conduct Disorder in Children of Drug Dependent Parents

    OpenAIRE

    Parvaresh, Nooshin; Ziaaddini, Hassan; Kheradmand, Ali; Bayati, Hamidreza

    2010-01-01

    Background Attention deficit hyperactivity disorder and conduct disorder are amongrelatively prevalent disorders during childhood and adolescence.Considering the negative impact of the parents' drug dependency andbipolar disorder, the present study aimed to determine the prevalence ofADHD and conduct disorder in children of drug-dependent and bipolar parents. Methods In this case-control study, the case group included two groups ofpatients with drug dependency and bipolar disorder hospitalize...

  12. Anxiety and Mood Disorders in Adolescents with Childhood Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Bagwell, Catherine L.; Molina, Brooke S.G.; Kashdan, Todd B.; Pelham, William E.; Hoza, Betsy

    2006-01-01

    In this study, the authors examined the association between childhood attention-deficit/hyperactivity disorder (ADHD) and anxiety and mood disorders in adolescence. They compared a group of 142 adolescents ages 13 to 18 years with a history of ADHD in childhood to group of 100 community-recruited adolescents without ADHD. The two groups did not…

  13. Childhood Attention-Deficit/Hyperactivity Disorder and Future Substance Use Disorders: Comparative Meta-Analyses

    Science.gov (United States)

    Charach, Alice; Yeung, Emanuela; Climans, Troy; Lillie, Erin

    2011-01-01

    Objective: In recent years cohort studies have examined childhood attention-deficit/hyperactivity disorder (ADHD) as a risk factor for substance use disorders (SUDs) in adolescence and young adulthood. The long-term risk is estimated for development of alcohol, cannabis, combined alcohol and psychoactive SUDs, combined SUDs (nonalcohol), and…

  14. Autonomic reactivity in clinically referred children attention-deficit/hyperactivity disorder versus anxiety disorder

    NARCIS (Netherlands)

    van Lang, Natasja D. J.; Tulen, Joke H. M.; Kallen, Victor L.; Rosbergen, Bianca; Dieleman, Gwen; Ferdinand, Robert F.

    2007-01-01

    This study examined whether children with attention-deficit/hyperactivity disorder (ADHD) have lower autonomic nervous system (ANS) activity and show less stress reactivity than children with an anxiety disorder. It also explored whether such a difference was accounted for by comorbid oppositional d

  15. Sleep Patterns in Children with Attention-Deficit/Hyperactivity Disorder, Tic Disorder, and Comorbidity

    Science.gov (United States)

    Kirov, Roumen; Kinkelbur, Joerg; Banaschewski, Tobias; Rothenberger, Aribert

    2007-01-01

    Background: In children, attention-deficit/hyperactivity disorder (ADHD), tic disorder (TD), and their coexistence (ADHD + TD comorbidity) are very common and clinically important. Associated sleep patterns and their clinical role are still insufficiently investigated. This study aimed at characterizing these sleep patterns in children with ADHD,…

  16. Memory in Early Onset Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder: Similarities and Differences

    Science.gov (United States)

    Udal, Anne H.; Oygarden, Bjorg; Egeland, Jens; Malt, Ulrik F.; Groholt, Berit

    2012-01-01

    Differentiating between early-onset bipolar disorder (BD) and attention-deficit/hyperactivity disorder (ADHD) can be difficult. Memory problems are commonly reported in BD, and forgetfulness is among the diagnostic criteria for ADHD. We compared children and adolescents with BD (n = 23), ADHD combined type (ADHD-C; n = 26), BD + ADHD-C (n = 15),…

  17. Fine Motor Skills in Attention Deficit Hyperactivity Disorder and Developmental Coordination Disorder

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2006-03-01

    Full Text Available The manual dexterity subtests of the Movement Assessment Battery for Children, and handwriting and computerized graphomotor tasks were used to investigate motor skills of a group of 12 children (11 males, 1 female; mean age 9 years 7 months with attention deficit hyperactivity disorder (ADHD and developmental coordination disorder (DCD and 12 controls at University Medical Centre Groningen, the Netherlands.

  18. Fine Motor Skills in Attention Deficit Hyperactivity Disorder and Developmental Coordination Disorder

    OpenAIRE

    J Gordon Millichap

    2006-01-01

    The manual dexterity subtests of the Movement Assessment Battery for Children, and handwriting and computerized graphomotor tasks were used to investigate motor skills of a group of 12 children (11 males, 1 female; mean age 9 years 7 months) with attention deficit hyperactivity disorder (ADHD) and developmental coordination disorder (DCD) and 12 controls at University Medical Centre Groningen, the Netherlands.

  19. A Comprehensive Investigation of Memory Impairment in Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder

    Science.gov (United States)

    Rhodes, Sinead M.; Park, Joanne; Seth, Sarah; Coghill, David R.

    2012-01-01

    Background: We conducted a comprehensive and systematic assessment of memory functioning in drug-naive boys with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Methods: Boys performed verbal and spatial working memory (WM) component (storage and central executive) and verbal and spatial storage load tasks,…

  20. Emotional Face Identification in Youths with Primary Bipolar Disorder or Primary Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Seymour, Karen E.; Pescosolido, Matthew F.; Reidy, Brooke L.; Galvan, Thania; Kim, Kerri L.; Young, Matthew; Dickstein, Daniel P.

    2013-01-01

    Objective: Bipolar disorder (BD) and attention-deficit/hyperactivity disorder (ADHD) are often comorbid or confounded; therefore, we evaluated emotional face identification to better understand brain/behavior interactions in children and adolescents with either primary BD, primary ADHD, or typically developing controls (TDC). Method: Participants…

  1. Brief Report: Prevalence of Attention Deficit/Hyperactivity Disorder among Individuals with an Autism Spectrum Disorder

    Science.gov (United States)

    Hanson, Ellen; Cerban, Bettina M.; Slater, Chelsea M.; Caccamo, Laura M.; Bacic, Janine; Chan, Eugenia

    2013-01-01

    Currently, both the DSM-IV-TR and ICD-10 preclude the diagnosis of Attention Deficit/Hyperactivity Disorder (ADHD) in cases that present with an Autism Spectrum Disorder (ASD). This criterion will be removed in the upcoming DSM-V, but the relationship between ASD and ADHD, and in particular the prevalence of ADHD among the ASD population, remains…

  2. Attention-deficit-hyperactivity disorder and reward deficiency syndrome

    Directory of Open Access Journals (Sweden)

    Kenneth Blum

    2008-11-01

    Full Text Available Kenneth Blum1,6,7,8,9,10, Amanda Lih-Chuan Chen2, Eric R Braverman3,9, David E Comings4, Thomas JH Chen5, Vanessa Arcuri9, Seth H Blum6, Bernard W Downs7,8, Roger L Waite7, Alison Notaro9, Joel Lubar10, Lonna Williams7, Thomas J Prihoda11, Tomas Palomo12, Marlene Oscar-Berman131Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC; 2Department of Engineering and Management of Advanced Technology, Chang Jung University, Tainan, Taiwan, Republic of China; 3Department of Neurosurgery, Weill College of Medicine, New York, NY; 4Department of Medical Genetics, City of Hope Medical Center, Duarte, CA; 5Department of Occupational Safety and Health, Chang Jung University, Tainan, Taiwan, Republic of China; 6Department of Psychoneurogenetics, Synapatamine, Inc., San Antonio, TX; 7LifeGen, Inc., La Jolla, CA; 8Allied Nutraceutical Research, Lederach, PA; 9PATH Research Foundation, New York, NY; 10Department of Physiology, University of Tennessee, Knoxville, TN; 11Department of Pathology, University of Texas Health Science Center, San Antonio, TX; 12Hospital Universitario 12 de Octubre, Madrid, Spain; 13Boston University School of Medicine, and Boston VA Healthcare System, Boston, MAParts of this manuscript have been published in Theor Biol Med Model (Comings et al 2005, which is an open access journalAbstract: Molecular genetic studies have identified several genes that may mediate susceptibility to attention deficit hyperactivity disorder (ADHD. A consensus of the literature suggests that when there is a dysfunction in the “brain reward cascade,” especially in the dopamine system, causing a low or hypo-dopaminergic trait, the brain may require dopamine for individuals to avoid unpleasant feelings. This high-risk genetic trait leads to multiple drug-seeking behaviors, because the drugs activate release of dopamine, which can diminish abnormal cravings. Moreover, this genetic trait is due in part to a

  3. Duration-dependence of the effect of treadmill exercise on hyperactivity in attention deficit hyperactivity disorder rats

    OpenAIRE

    Ji, Eun-Sang; Kim, Chang-Ju; Park, Jun Heon; Bahn, Geon Ho

    2014-01-01

    Attention-deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder, and its symptoms are hyperactivity and deficits in learning and memory. Physical exercise increases dopamine synthesis and neuronal activity in various brain regions. In the present study, we investigate the duration-dependence of the treadmill exercise on hyperactivity in relation with dopamine expression in ADHD. Spontaneously hypertensive rats were used for the ADHD rats and Wistar-Kyoto rats were used fo...

  4. Attention Mechanisms in Children with Anxiety Disorders and in Children with Attention Deficit Hyperactivity Disorder: Implications for Research and Practice

    Science.gov (United States)

    Weissman, Adam S.; Chu, Brian C.; Reddy, Linda A.; Mohlman, Jan

    2012-01-01

    Inattention is among the most commonly referred problems for school-aged youth. Research suggests distinct mechanisms may contribute to attention problems in youth with anxiety disorders versus youth with attention deficit hyperactivity disorder (ADHD). This study compared children (8-17 years) with anxiety disorders (n = 24) and children (8-16…

  5. A Multiple Deficit Model of Reading Disability and Attention-Deficit/Hyperactivity Disorder: Searching for Shared Cognitive Deficits

    Science.gov (United States)

    McGrath, Lauren M.; Pennington, Bruce F.; Shanahan, Michelle A.; Santerre-Lemmon, Laura E.; Barnard, Holly D.; Willcutt, Erik G.; DeFries, John C.; Olson, Richard K.

    2011-01-01

    Background: This study tests a multiple cognitive deficit model of reading disability (RD), attention-deficit/hyperactivity disorder (ADHD), and their comorbidity. Methods: A structural equation model (SEM) of multiple cognitive risk factors and symptom outcome variables was constructed. The model included phonological awareness as a unique…

  6. Dopamine Transporter Genotype Conveys Familial Risk of Attention-Deficit/Hyperactivity Disorder through Striatal Activation

    Science.gov (United States)

    Durston, Sarah; Fossella, John A.; Mulder, Martijn J.; Casey B. J.; Ziermans, Tim B.; Vessaz, M. Nathalie; Van Engeland, Herman

    2008-01-01

    The study examines the effect of the dopamine transporter (DAT1) genotype in attention-deficit/hyperactivity disorder (ADHD). The results confirm that DAT1 translates the genetic risk of ADHD through striatal activation.

  7. Helping Children and Youth with Attention-Deficit/Hyperactivity Disorder: Systems of Care

    Science.gov (United States)

    ... to a mental health care provider. Misperceptions and misunderstandings can lead to delayed diagnoses, misdiagnoses, or no ... Timothy copes with attention-deficit/ hyperactivity disorder (ADHD),depression, learning disabilities, and alcoholism. Timothy was diagnosed with ...

  8. Narrative Intervention: A School-Based Counseling Strategy for Students with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Kamali, Khosrow; Yoosefi Looyeh, Majid

    2013-01-01

    This article describes a group narrative intervention for improving the behavior of 8- to 11-year-old children with attention-deficit/hyperactivity disorder at home and school. (Contains 2 tables and 1 note.)

  9. Career Beliefs and Job Satisfaction in Adults with Symptoms of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Painter, Carol A.; Prevatt, Frances; Welles, Theresa

    2008-01-01

    The authors evaluated dysfunctional career beliefs and subsequent low job satisfaction in adults reporting significant symptoms of attention-deficit/hyperactivity disorder (ADHD). Participants (N = 81) completed the Adult Attention Deficit Disorders Evaluation Scale (S. B. McCarney & P. D. Anderson, 1996), the Career Thoughts Inventory (J. P.…

  10. Electroencephalography signatures of attention-deficit/hyperactivity disorder: clinical utility

    Directory of Open Access Journals (Sweden)

    Alba G

    2015-10-01

    Full Text Available Guzmán Alba,1 Ernesto Pereda,2 Soledad Mañas,3 Leopoldo D Méndez,3 Almudena González,1 Julián J González1 1Physiology Unit, Health Sciences Faculty (S Medicine, 2Department of Industrial Engineering, School of Engineering and Technology, University of La Laguna, 3Clinical Neurophysiology Unit, University Hospital La Candelaria, Tenerife, Spain Abstract: The techniques and the most important results on the use of electroencephalography (EEG to extract different measures are reviewed in this work, which can be clinically useful to study subjects with attention-deficit/hyperactivity disorder (ADHD. First, we discuss briefly and in simple terms the EEG analysis and processing techniques most used in the context of ADHD. We review techniques that both analyze individual EEG channels (univariate measures and study the statistical interdependence between different EEG channels (multivariate measures, the so-called functional brain connectivity. Among the former ones, we review the classical indices of absolute and relative spectral power and estimations of the complexity of the channels, such as the approximate entropy and the Lempel-Ziv complexity. Among the latter ones, we focus on the magnitude square coherence and on different measures based on the concept of generalized synchronization and its estimation in the state space. Second, from a historical point of view, we present the most important results achieved with these techniques and their clinical utility (sensitivity, specificity, and accuracy to diagnose ADHD. Finally, we propose future research lines based on these results. Keywords: EEG, ADHD, power spectrum, functional connectivity, clinical assessment

  11. Factors of teachers' competence for teaching students with attention deficit hyperactivity disorder (ADHD)

    OpenAIRE

    Pulec Lah, Suzana

    2013-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) is the most frequently diagnosed disorder during the childhood period. Prevalence estimates of ADHD among the school population vary, with the dominating estimates ranging from 3 to 7 per cent (APA, 2000; NCCMH, 2009). The characteristic features that are primarily defined as attention deficit, impulsivity and hyperactivity by diagnostic classifications may to a great extent inhibit a person’s functioning in every important aspect of their life....

  12. Neurofibromatosis type 1 and attention deficit hyperactivity disorder: a case study and literature review

    OpenAIRE

    Miguel CS; Chaim-Avancini TM; MA Silva; Louzã MR

    2015-01-01

    Carmen Sílvia Miguel, Tiffany M Chaim-Avancini, Maria Aparecida Silva, Mario Rodrigues LouzãAdult Attention Deficit Hyperactivity Disorder Program (PRODATH), Institute of Psychiatry, University of São Paulo, São Paulo, BrazilBackground: The cognitive profile of children with neurofibromatosis type 1 (NF1) and attention deficit hyperactivity disorder (ADHD) has been well characterized, but few studies have evaluated the cognitive abilities of adults with NF1 an...

  13. Effects of Self-monitoring Technique on Inattentive Behaviors of Students with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Bagher Ghobari Bonab; Mir Mahmoud Mirnasab

    2011-01-01

    Beneficial effects of stimulants on core symptoms of Attention Deficit Hyperactivity Disorder (ADHD) have been reported in several studies. Behavioral interventions have also been proposed as empirically supported interventions for ADHD. Although cognitive-behavioral therapies (CBT) have been criticized for the lack of evidence-based data, some studies have indicated the positive effects of CBT techniques on children with attention deficit hyperactivity disorder (ADHD). This article reports t...

  14. Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents

    DEFF Research Database (Denmark)

    Storebø, Ole Jakob; Pedersen, Nadia; Ramstad, Erica;

    2016-01-01

    This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the harmful effects of methylphenidate treatment for children and adolescents with attention deficit hyperactivity disorder (ADHD) in non-randomised studies.......This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the harmful effects of methylphenidate treatment for children and adolescents with attention deficit hyperactivity disorder (ADHD) in non-randomised studies....

  15. FROM WORK EXPERIENCE IN ADVANCED TRAINING OF NORWEGIAN TEACHERS IN ATTENTION DEFICIT HYPERACTIVITY DISORDER

    OpenAIRE

    Bakken, Anne

    2014-01-01

    The article presents the experience of building competence of educators in attention deficit hyperactivity disorder in Norway. The course “Attention deficit hyperactivity disorder, Tourette syndrome, Asperger syndrome” is included in the curriculum of “Special education”. The course is divided into training modules of 10 credits (points). The courses are funded by regional administrations and local authorities, who pay for staff training, thus supporting the state system of special education....

  16. Color naming deficits and attention-deficit/hyperactivity disorder: A retinal dopaminergic hypothesis

    OpenAIRE

    Tannock Rosemary; Banaschewski Tobias; Gold David

    2006-01-01

    Abstract Background Individuals with Attention-Deficit/Hyperactive Disorder (ADHD) have unexplained difficulties on tasks requiring speeded processing of colored stimuli. Color vision mechanisms, particularly short-wavelength (blue-yellow) pathways, are highly sensitive to various diseases, toxins and drugs that alter dopaminergic neurotransmission. Thus, slow color processing might reflect subtle impairments in the perceptual encoding stage of stimulus color, which arise from hypodopaminergi...

  17. Vitamin D Status at Birth and Future Risk of Attention Deficit/Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    Rylander, Lars; Lindh, Christian H.; Jönsson, Bo A. G.; Ode, Amanda; Olofsson, Per; Ivarsson, Sten A.; Rignell-Hydbom, Anna; Haglund, Nils

    2015-01-01

    Objective To investigate whether children with Attention Deficit/Hyperactivity Disorder have lower levels of Vitamin D3 at birth than matched controls. Material Umbilical cord blood samples collected at birth from 202 children later diagnosed with Attention Deficit/Hyperactivity Disorder were analysed for vitamin D content and compared with 202 matched controls. 25-OH vitamin D3 was analysed by liquid chromatography tandem mass spectrometry. Results No differences in cord blood vitamin D concentration were found between children with Attention Deficit/Hyperactivity Disorder (median 13.0 ng/ml) and controls (median 13.5 ng/ml) (p = 0.43). In a logistic regression analysis, Attention Deficit/Hyperactivity Disorder showed a significant association with maternal age (odds ratio: 0.96, 95% confidence interval: 0.92–0.99) but not with vitamin D levels (odds ratio: 0.99, 95% confidence interval: 0.97–1.02). Conclusion We found no difference in intrauterine vitamin D levels between children later developing Attention Deficit/Hyperactivity Disorder and matched control children. However, the statistical power of the study was too weak to detect an eventual small to medium size association between vitamin D levels and Attention Deficit/Hyperactivity Disorder. PMID:26509435

  18. Meta-Analysis: Treatment of Attention-Deficit/Hyperactivity Disorder in Children with Comorbod Tic Disorders

    Science.gov (United States)

    Bloch, Michael H.; Panza, Kaitlyn E.; Landeros-Weisenberger, Angeli; Leckman, James F.

    2009-01-01

    Methylphenidate appears to provide the greatest and most immediate improvement of the symptoms of attention deficit hyperactivity disorder and does not appear to worsen tic symptoms based on a meta-analysis study. The meta-analysis included nine studies with 477 subjects.

  19. Treatment Programs for Students With Attention Deficit Hyperactivity Disorder: A Meta-Analysis Study

    OpenAIRE

    Mihandoost, Zeinab

    2015-01-01

    Context: The aim of this study was to determine the experimental evidence of treatment/intervention programs for deficits in social skills, attention, and behavioral disorder in children and adolescents with attention deficit hyperactivity disorder (ADHD). Evidence Acquisition: Meta-analysis procedures were employed to investigate whether children and adolescents with ADHD exhibit deficits in attention and social skills. A total of 17 empirical research studies published between 2000 and 2013...

  20. Diagnosis of Attention-Deficit/Hyperactivity Disorder and Its Behavioral, Neurological, and Genetic Roots

    Science.gov (United States)

    Mueller, Kathryn L.; Tomblin, J. Bruce

    2012-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a common developmental disorder often associated with other developmental disorders including speech, language, and reading disorders. Here, we review the principal features of ADHD and current diagnostic standards for the disorder. We outline the ADHD subtypes, which are based upon the dimensions…

  1. Meta-Analysis of Attention-Deficit/Hyperactivity Disorder or Attention-Deficit/Hyperactivity Disorder Symptoms, Restriction Diet, and Synthetic Food Color Additives

    Science.gov (United States)

    Nigg, Joel T.; Lewis, Kara; Edinger, Tracy; Falk, Michael

    2012-01-01

    Objective: The role of diet and of food colors in attention-deficit/hyperactivity disorder (ADHD) or its symptoms warrants updated quantitative meta-analysis, in light of recent divergent policy in Europe and the United States. Method: Studies were identified through a literature search using the PubMed, Cochrane Library, and PsycNET databases…

  2. Neuropsychological Functioning in Children with Tourette Syndrome with and without Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Sukhodolsky, Denis G.; Landeros-Weisenberger, Angeli; Scahill, Lawrence; Leckman, James F.; Schultz, Robert T.

    2010-01-01

    Objective: Neuropsychological functioning in children with Tourette syndrome (TS) has been characterized by subtle deficits in response inhibition, visual-motor integration, and fine-motor coordination. The association of these deficits with the tics of the TS versus co-occurring attention-deficit/hyperactivity disorder (ADHD) has not been well…

  3. Early Development of Comorbidity Between Symptoms of Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder

    OpenAIRE

    Harvey, Elizabeth A.; Breaux, Rosanna P.; Lugo-Candelas, Claudia I.

    2016-01-01

    Attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are among the most common childhood disorders and frequently co-occur. The present study sought to advance our understanding of how comorbidity between ADHD and ODD develops during the preschool years by testing a cross-lagged model that integrates two prominent models: the developmental precursor model and the correlated risk factors model. Participants were 199 children (107 boys) who took part in a long...

  4. Association between severity of behavioral phenotype and comorbid attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders

    OpenAIRE

    Rao, Patricia A; Landa, Rebecca J.

    2013-01-01

    Autism spectrum disorder and attention deficit hyperactivity disorder are neurodevelopmental disorders that cannot be codiagnosed under existing diagnostic guidelines (Diagnostic and Statistical Manual of the American Psychiatric Association, 4th ed., text rev.). However, reports are emerging that attention deficit hyperactivity disorder is sometimes comorbid with autism spectrum disorder. In the current study, we examined rates of parent-reported clinically significant symptoms of attention ...

  5. Comparative Efficacy of Iranian and Foreign Methylphenidate in Children with Attention Deficit Hyperactive Disorder

    OpenAIRE

    M Karahmadi; H Esmaili

    2008-01-01

    ABSTRACT: Introduction & Objective: Methylphenidate is one of the basic drugs in treating ADHD. According to many clinical studies, the foreign form of methylphenidate (ritalin) is more efficient than the Iranian form of the drug (stimidate). This study aimed to compare the efficacy of stimidate and Ritalin in the treatment of attention deficit hyperactive disorder. Materials & Methods: In this double blind, randomized clinical trial, 200 children with attention deficit hyperactive d...

  6. Impulsive Aggression as a Comorbidity of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

    OpenAIRE

    Saylor, Keith E.; Amann, Birgit H.

    2016-01-01

    Abstract Objective: This article examines the characteristics of impulsive aggression (IA) as a comorbidity in children and adolescents with attention-deficit/hyperactivity disorder (ADHD), focusing on its incidence, impact on ADHD outcomes, need for timely intervention, and limitations of current treatment practices. Methods: Relevant literature was retrieved with electronic searches in PubMed and PsycINFO using the search strategy of “ADHD OR attention deficit hyperactivity disorder” AND “i...

  7. Electrophysiological Indices of Abnormal Error-Processing in Adolescents with Attention Deficit Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    Groom, Madeleine J.; Cahill, John D.; Bates, Alan T.; Jackson, Georgina M.; Calton, Timothy G.; Liddle, Peter F.; Hollis, Chris

    2010-01-01

    Background: Impaired cognitive control has been frequently observed in children and young people with attention deficit hyperactivity disorder (ADHD) and might underlie the excessive hyperactivity and impulsivity in this population. We investigated behavioural and electrophysiological indices relevant to one domain of cognitive control; namely…

  8. A Weak Association between Traits of Attention-Deficit/Hyperactivity Disorder and Gambling in College Students

    Science.gov (United States)

    Canu, Will H.; Schatz, Nicole K.

    2011-01-01

    Attention-Deficit/Hyperactivity Disorder (ADHD) has been characterized as a comorbidity to pathological gambling (PG). However, contradictory evidence has emerged, and it has not been established whether nonimpulsive features of ADHD (e.g., inattention, hyperactivity) contribute to PG risk, or how robust this relationship is in college samples.…

  9. Factor Structure of Attention Deficit Hyperactivity Disorder Symptoms for Children Age 3 to 5 Years

    Science.gov (United States)

    McGoey, Kara E.; Schreiber, James; Venesky, Lindsey; Westwood, Wendy; McGuirk, Lindsay; Schaffner, Kristen

    2015-01-01

    The diagnosis of attention deficit hyperactivity disorder (ADHD) distinguishes two dimensions of symptoms, inattention and hyperactivity-impulsivity for ages 3 to adulthood. Currently, no separate classification for preschool-age children exists, whereas preliminary research suggests that the two-factor structure of ADHD may not match the…

  10. Students Diagnosed with Attention Deficit Hyperactivity Disorder: Collaborative Strategies for School Counselors

    Science.gov (United States)

    Shillingford-Butler, M. Ann; Theodore, Lea

    2013-01-01

    The school setting can be a difficult place for children with attention deficit hyperactivity disorder (ADHD). The core symptoms of ADHD, which include inattention, hyperactivity, and impulsivity, make meeting the curriculum demands of the classroom challenging. That ADHD negatively impacts not only academic performance but also social and…

  11. Can attention deficit hyperactivity disorder and fetal alcohol spectrum disorder be differentiated by motor and balance deficits?

    NARCIS (Netherlands)

    Kooistra, Libbe; Ramage, Barbara; Crawford, Susan; Cantell, Marja; Wormsbecker, Shirley; Gibbard, Ben; Kaplan, Bonnie J

    2009-01-01

    There is an ongoing debate regarding the diagnostic overlap between Attention Deficit Hyperactivity Disorder (ADHD) and Fetal Alcohol Spectrum Disorder (FASD). Differential diagnosis is important because of treatment implications. Children aged 7-10years (47 ADHD, 30 FASD, 39 controls) participated.

  12. Understanding the Comorbidity between Dyslexia and Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Boada, Richard; Willcutt, Erik G.; Pennington, Bruce F.

    2012-01-01

    Dyslexia and attention-deficit/hyperactivity disorder (ADHD) are 2 of the most prevalent complex neurodevelopmental disorders of childhood, each affecting approximately 5% of the population in the United States. These disorders are also each comorbid with speech sound disorder and language impairment. Understanding the nature of the comorbidity…

  13. Comparative efficacy of methylphenidate and atomoxetine in oppositional defiant disorder comorbid with attention deficit hyperactivity disorder

    OpenAIRE

    Garg, Jasmin; Arun, Priti; Chavan, BS

    2015-01-01

    Background: Oppositional defiant disorder (ODD) is frequently comorbid with attention deficit hyperactivity disorder (ADHD) and is associated with substantial functional impairments. Methylphenidate and atomoxetine are well-established drugs for the management of ADHD. Some studies from Western countries have reported these drugs to be effective in the management of ODD comorbid with ADHD. This study aimed to assess if methylphenidate and atomoxetine are efficacious in treating Indian childre...

  14. Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders

    OpenAIRE

    Yerys, Benjamin E.; Wallace, Gregory L.; Sokoloff, Jennifer L.; Shook, Devon A.; James, Joette D.; Kenworthy, Lauren

    2009-01-01

    Recent estimates suggest that over 30% of children with autism spectrum disorders (ASD) meet diagnostic criteria for attention deficit/hyperactivity disorder (ADHD), and another 20% of children with ASD exhibit subthreshold clinical ADHD symptoms. Presence of ADHD symptoms in the context of ASD could have a variety of effects on cognition, autistic traits, and adaptive/maladaptive behaviors including: exacerbating core ASD impairments; adding unique impairments specific to ADHD; producing new...

  15. Gender Differences in Associations Between Attention-Deficit/Hyperactivity Disorder and Substance Use Disorder

    OpenAIRE

    Ottosen, Cæcilie; Petersen, Liselotte; Tidselbak Larsen, Janne; Dalsgaard, Søren

    2015-01-01

    ObjectiveTo examine gender differences in the association between attention-deficit/hyperactivity disorder (ADHD) and substance use disorder (SUD), and to explore the impact of comorbid psychiatric conditions.MethodThis was a cohort study of all children born in Denmark in 1990-2003 (n=729,560). By record linkage across nationwide registers, we merged data on birth characteristics, socioeconomic status, familial psychiatric history, and diagnoses of ADHD, comorbidities, and SUD. Hazard ratios...

  16. Associations between substance use disorder and attention-deficit/hyperactivity disorder

    OpenAIRE

    Krantz, Sofia Birgitta, 1983-

    2012-01-01

    Accumulated research points to certain associations between substance use disorder (SUD) and attention-deficit/hyperactivity disorder (ADHD). The intent of this thesis was to examine associations between SUD and ADHD among Icelandic adults. In line with results of earlier studies, it was hypothesized that individuals with ADHD are diagnosed with SUD at an earlier age and show shorter times of abstinence than individuals without ADHD. A positive correlation was predicted between age at offset ...

  17. Influence of Methylphenidate on Motor Performance and Attention in Children with Developmental Coordination Disorder and Attention Deficit Hyperactive Disorder

    Science.gov (United States)

    Bart, Orit; Daniel, Liron; Dan, Orrie; Bar-Haim, Yair

    2013-01-01

    Individuals with attention deficit hyperactive disorder (ADHD) often have coexisting developmental coordination disorder (DCD). The positive therapeutic effect of methylphenidate on ADHD symptoms is well documented, but its effects on motor coordination are less studied. We assessed the influence of methylphenidate on motor performance in children…

  18. Attention Deficit Hyperactivity Disorder and Social Anxiety in İstanbul Heavy Metal Bar Patrons

    OpenAIRE

    Ekinci, Özalp; Bez, Yasin; Topçuoglu, Volkan; Nurmedow, Serdar

    2011-01-01

    Objective: We aimed to examine the heavy metal bar patrons in Istanbul by means of self-reported questionnaires for psychiatric disorder symptoms. Material and Methods: Seventy-one volunteers from 4 popular heavy metal bars were included to the study. The Beck Depression Inventory, the Liebowitz Social Anxiety Scale (LSAS), the Adult Attention Deficit Disorder/Attention Deficit and Hyperactivity Disorder (ADD/ADHD) Scale and the Michigan Alcoholism Screening Test (MAST) were adminis...

  19. Attention Deficit Hyperactivity Disorder and Social Anxiety in İstanbul Heavy Metal Bar Patrons

    OpenAIRE

    Özalp Ekinci; Yasin Bez; Volkan Topçuoglu; Serdar Nurmedow

    2011-01-01

    Objective: We aimed to examine the heavy metal bar patrons in Istanbul by means of self-reported questionnaires for psychiatric disorder symptoms.Material and Methods: Seventy-one volunteers from 4 popular heavy metal bars were included to the study. The Beck Depression Inventory, the Liebowitz Social Anxiety Scale (LSAS), the Adult Attention Deficit Disorder/Attention Deficit and Hyperactivity Disorder (ADD/ADHD) Scale and the Michigan Alcoholism Screening Test (MAST) were administered to th...

  20. Structural Brain Abnormalities in Adolescents with Autism Spectrum Disorder and Patients with Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Brieber, Sarah; Neufang, Susanne; Bruning, Nicole; Kamp-Becker, Inge; Remschmidt, Helmut; Herpertz-Dahlmann, Beate; Fink, Gereon R.; Konrad, Kerstin

    2007-01-01

    Background: Although autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are two distinct neurodevelopmental diseases, they share behavioural, neuropsychological and neurobiological characteristics. For the identification of endophenotypes across diagnostic categories, further investigations of phenotypic overlap…

  1. A Possible Coexistence between Restless Leg Syndrom and Attention Deficit Hyperactivity Disorder

    DEFF Research Database (Denmark)

    Tilma, Jørgen; Thomsen, Per Hove; Ostergaard, John R

    2014-01-01

    Restless legs syndrome (RLS) and attention deficit hyperactivity disorder (ADHD) have consistently been found to coexist frequently. The cause for the relationship of these co-morbid disorders is contradicting, but both disorders are associated with a common dopaminergic dysfunction, low iron...

  2. Sleep Problems in Children with Autism, Attention-Deficit Hyperactivity Disorder, and Epilepsy

    Science.gov (United States)

    Tsai, Fang-Ju; Chiang, Huey-Ling; Lee, Chi-Mei; Gau, Susan Shur-Fen; Lee, Wang-Tso; Fan, Pi-Chuan; Wu, Yu-Yu; Chiu, Yen-Nan

    2012-01-01

    This study aimed to examine sleep problems in children with autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD), and epilepsy in clinical settings. We assessed 64 children with ASD, 64 with ADHD, 64 with epilepsy, and 64 typically developing children without any neuropsychiatric disorders by using a sex-and age-matched…

  3. Attention-deficit hyperactivity disorder on the frontlines: management in the primary care office.

    Science.gov (United States)

    Taylor, M A

    1999-01-01

    Attention-deficit hyperactivity disorder (ADHD) is a common, disabling pediatric psychiatric disorder. Diagnosis of this disorder requires systematic data collection from multiple sources. The preferred therapy for ADHD is a combination of behavioral modification, educational assistance, and stimulant medications. PMID:10470515

  4. Attention-Deficit/Hyperactivity Disorder among Children with and without Intellectual Disability: An Examination across Time

    Science.gov (United States)

    Neece, C. L.; Baker, B. L.; Blacher, J.; Crnic, K. A.

    2011-01-01

    Background: Children with intellectual and developmental disabilities are at heightened risk for mental disorders, and disruptive behaviour disorders appear to be the most prevalent. The current study is a longitudinal examination of attention-deficit/hyperactivity disorder (ADHD) among children with and without intellectual disability (ID) across…

  5. Neuropsychological Functioning in Childhood-Onset Psychosis and Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Brodsky, Kimberly; Willcutt, Erik G.; Davalos, Deana B.; Ross, Randal G.

    2014-01-01

    Background: Attention-deficit/hyperactivity disorder (ADHD) and childhood-onset psychosis (COP) are chronic, heterogeneous disorders with symptoms that frequently co-occur, but the etiology of their comorbidity is unknown. Studies of each disorder indicate that both ADHD and COP are associated with a range of neuropsychological weaknesses, but few…

  6. Attention-deficit hyperactivity disorder: recent advances in paediatric pharmacotherapy.

    Science.gov (United States)

    May, Diane E; Kratochvil, Christopher J

    2010-01-01

    Throughout this decade, there has been significant research into pharmacotherapies for attention-deficit hyperactivity disorder (ADHD). This article considers the efficacy and safety of five of the more novel long-acting pharmacological treatments recently approved by the FDA for marketing in the US for paediatric ADHD, along with an alpha(2)-adrenoceptor agonist in preparation. Reviewed treatments include the non-stimulant atomoxetine, three novel extended-release (XR) stimulant preparations: dexmethylphenidate, lisdexamfetamine dimesylate and the methylphenidate transdermal system (TDS), and the recently approved XR alpha(2)-adrenoceptor agonist, guanfacine. Dexmethylphenidate XR is a stimulant treatment in a single isomer form, and has an efficacy and tolerability similar to two doses of immediate-release (IR) dexmethylphenidate when taken 4 hours apart, but is dosed at half of the usual d,l-methylphenidate dose. Dexmethylphenidate XR utilizes a beaded bimodal release, with 50% initially released and another 50% released 4 hours later to provide benefit lasting up to 10-12 hours. Lisdexamfetamine was the first stimulant treatment approved as a prodrug, whereby the single isomer d-amfetamine remains pharmacologically inactive until activated by cleaving the lysine. Its efficacy and tolerability are generally consistent with that of XR mixed amfetamine salts, with this activation method and more consistent absorption generally resulting in up to an 11- to 13-hour benefit. The methylphenidate TDS patch utilizes skin absorption to provide predictable and uniform delivery of methylphenidate when worn for 9 hours/day. The efficacy and tolerability of the methylphenidate TDS patch is generally consistent with that of osmotic-controlled release oral system (OROS) methylphenidate, providing benefit for about 11-12 hours. Because of their formulation, lisdexamfetamine and methylphenidate each have an onset of effect at about 2 hours after administration. An adjustable

  7. Neuropsychological and neurophysiological approaches to study of variants of Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Matveyeva E. Yu.; Romanova A. A.; Yegorova O. I.; Agris A.R.

    2012-01-01

    The present review carries out analysis of empirical studies concerning neuropsychological and neurophysiological mechanisms of Attention Deficit Hyperactivity Disorder (ADHD). The current data, regarding malfunctions of brain systems at various levels of aetiopathogenesis (genetic, neurotrasmitting, functioning of separate brain structure), are discussed. The article regards the character of deficit in various components of psychic activity in people with ADHD, namely, executive functions an...

  8. Neural correlates of visuospatial working memory in attention-deficit/hyperactivity disorder and healthy controls

    NARCIS (Netherlands)

    van Ewijk, Hanneke; Weeda, Wouter D.; Heslenfeld, Dirk J.; Luman, Marjolein; Hartman, Catharina A.; Hoekstra, Pieter J.; Faraone, Stephen V.; Franke, Barbara; Buitelaar, Jan K.; Oosterlaan, Jaap

    2015-01-01

    Impaired visuospatial working memory (VSWM) is suggested to be a core neurocognitive deficit in attention-deficit/hyperactivity disorder (ADHD), yet the underlying neural activation patterns are poorly understood. Furthermore, it is unclear to what extent age and gender effects may play a role in VS

  9. Striatal Sensitivity during Reward Processing in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Paloyelis, Yannis; Mehta, Mitul A.; Faraone, Stephen V.; Asherson, Philip; Kuntsi, Jonna

    2012-01-01

    Objective: Attention-deficit/hyperactivity disorder (ADHD) has been linked to deficits in the dopaminergic reward-processing circuitry; yet, existing evidence is limited, and the influence of genetic variation affecting dopamine signaling remains unknown. We investigated striatal responsivity to rewards in ADHD combined type (ADHD-CT) using…

  10. Beyond ADHD: A Consideration of Attention Deficit Hyperactivity Disorder and Pedagogy in Australian Schools

    Science.gov (United States)

    Prosser, Brenton J.

    2008-01-01

    A psycho-medical discourse that explains behavioural dysfunction through neurological deficit has dominated debate about attention deficit hyperactivity disorder (ADHD). However, if only medical questions are asked, only medical answers will be found, resulting in more or less drug treatment. When behavioural dysfunction results in impairment…

  11. Attentional Profiles and White Matter Correlates in Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Type.

    Science.gov (United States)

    Rossi, Adriana Suzart Ungaretti; de Moura, Luciana Monteiro; de Mello, Claudia Berlim; de Souza, Altay Alves Lino; Muszkat, Mauro; Bueno, Orlando Francisco Amodeo

    2015-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a widely studied neurodevelopmental disorder. It is a highly heterogeneous condition, encompassing different types of expression. The predominantly inattentive type is the most prevalent and the most stable over the lifetime, yet it is the least-studied presentation. To increase understanding of its cognitive profile, 29 children with attention-deficit/hyperactivity disorder of predominantly inattentive type (ADHD-I) and 29 matched controls, aged 7-15 years, had their attentional abilities assessed through the Conners' continuous performance test. Diffusion tensor imaging data were collected for all of the participants using a 3.0-T MRI system. Fractional anisotropy (FA) values were obtained for 20 fiber tracts, and brain-behavior correlations were calculated for 42 of the children. The ADHD-I children differed significantly from the typically developing (TD) children with respect to attentional measures, such as the ability to maintain response-time consistency throughout the task (Hit RT SE and Variability), vigilance (Hit RT ISI and Hit RT ISI SE), processing speed (Hit RT), selective attention (Omissions), sustained attention (Hit RT Block Change), error profile (Response Style), and inhibitory control (Perseverations). Evidence of significant differences between the ADHD-I and the TD participants was not found with respect to the mean FA values in the fiber tracts analyzed. Moderate and strong correlations between performance on the attention indicators and the tract-average FA values were found for the ADHD-I group. Our results contribute to a better characterization of the attentional profile of ADHD-I individuals and suggest that in children and adolescents with ADHD-I, attentional performance is mainly associated with the white matter structure of the long associative fibers that connect anterior-posterior brain areas. PMID:26441684

  12. Comorbidity and confounding factors in attention-deficit/hyperactivity disorder and sleep disorders in children

    OpenAIRE

    Jan, Ya-Wen; Yang, Chien-Ming; Huang, Yu-Shu

    2011-01-01

    Sleep problems are commonly reported in children with attention-deficit/hyperactivity disorder (ADHD) symptoms. Research data regarding the complex and reciprocal relationship between ADHD and sleep disturbances has now accumulated. This paper is focused on the types of sleep problems that are associated with ADHD symptomatology, and attempts to untangle confounding factors and overlapping symptoms. The goal is also to present an updated overview of the pathophysiology of and treatment strate...

  13. The Comorbidity between Attention-Deficit/Hyperactivity Disorder (ADHD in Children and Arabic Speech Sound Disorder

    Directory of Open Access Journals (Sweden)

    Ruaa Osama Hariri

    2016-04-01

    Full Text Available Children with Attention-Deficiency/Hyperactive Disorder (ADHD often have co-existing learning disabilities and developmental weaknesses or delays in some areas including speech (Rief, 2005. Seeing that phonological disorders include articulation errors and other forms of speech disorders, studies pertaining to children with ADHD symptoms who demonstrate signs of phonological disorders in their native Arabic language are lacking. The purpose of this study is to provide a description of Arabic language deficits and to present a theoretical model of potential associations between phonological language deficits and ADHD. Dodd and McCormack’s (1995 four subgroups classification of speech disorder and the phonological disorders pertaining to the Arabic language provided by a Saudi Institute for Speech and Hearing are examined within the theoretical framework. Since intervention may improve articulation and focuses a child’s attention on the sound structure of words, findings in this study are based on the assumption that children with ADHD may acquire phonology for their Arabic language in the same way, and following the same developmental stages as intelligible children. Both quantitative and qualitative analyses have proven that the ADHD group analyzed in this study had indeed failed to acquire most of their Arabic consonants as they should have.Keywords: speech sound disorder, attention-deficiency/hyperactive, developmental disorder, phonological disorder, language disorder/delay, language impairment

  14. Attention Deficit Hyperactivity Disorder and Tuberous Sclerosis Complex

    Science.gov (United States)

    ... the diagnosis of ADHD are found in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5). It lists nine symptoms of inattention and nine of hyperactivity and impulsivity. To make a diagnosis of ADHD in children or adolescents, there must ...

  15. A brain-computer interface based attention training program for treating attention deficit hyperactivity disorder.

    Directory of Open Access Journals (Sweden)

    Choon Guan Lim

    Full Text Available UNLABELLED: Attention deficit hyperactivity disorder (ADHD symptoms can be difficult to treat. We previously reported that a 20-session brain-computer interface (BCI attention training programme improved ADHD symptoms. Here, we investigated a new more intensive BCI-based attention training game system on 20 unmedicated ADHD children (16 males, 4 females with significant inattentive symptoms (combined and inattentive ADHD subtypes. This new system monitored attention through a head band with dry EEG sensors, which was used to drive a feed forward game. The system was calibrated for each user by measuring the EEG parameters during a Stroop task. Treatment consisted of an 8-week training comprising 24 sessions followed by 3 once-monthly booster training sessions. Following intervention, both parent-rated inattentive and hyperactive-impulsive symptoms on the ADHD Rating Scale showed significant improvement. At week 8, the mean improvement was -4.6 (5.9 and -4.7 (5.6 respectively for inattentive symptoms and hyperactive-impulsive symptoms (both p<0.01. Cohen's d effect size for inattentive symptoms was large at 0.78 at week 8 and 0.84 at week 24 (post-boosters. Further analysis showed that the change in the EEG based BCI ADHD severity measure correlated with the change ADHD Rating Scale scores. The BCI-based attention training game system is a potential new treatment for ADHD. TRIAL REGISTRATION: ClinicalTrials.gov NCT01344044.

  16. Personality Disorder in Adult Attention-Deficit/Hyperactivity Disorder: Attrition and Change During Long-term Treatment.

    Science.gov (United States)

    Gift, Thomas E; Reimherr, Frederick W; Marchant, Barrie K; Steans, Tammy A; Wender, Paul H

    2016-05-01

    Personality disorders (PDs) are commonly found in adults with attention-deficit/hyperactivity disorder (ADHD) and are associated with increased ADHD symptoms and psychosocial impairment. To assess the impact of PDs or personality traits on retention rates in ADHD trials and whether treating ADHD affects the expression of PD, data were analyzed from 2 methylphenidate trials. Assessment of PDs and personality traits included using the Wisconsin Personality Disorders Inventory IV and the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders. Attention-deficit/hyperactivity disorder symptoms were evaluated using the Wender-Reimherr Adult Attention Deficit Disorder Scale. Major findings were that subjects with cluster A, cluster B, passive-aggressive, or more than 1 PD showed more attrition. Subjects dropping out also had more schizoid and narcissistic traits. Attention-deficit/hyperactivity disorder symptoms (p Disorders Inventory IV items that improved most, 8 resembled ADHD or oppositional defiant disorder symptoms. PMID:27082828

  17. Association between Severity of Behavioral Phenotype and Comorbid Attention Deficit Hyperactivity Disorder Symptoms in Children with Autism Spectrum Disorders

    Science.gov (United States)

    Rao, Patricia A.; Landa, Rebecca J.

    2014-01-01

    Autism spectrum disorder and attention deficit hyperactivity disorder are neurodevelopmental disorders that cannot be codiagnosed under existing diagnostic guidelines ("Diagnostic and Statistical Manual of the American Psychiatric Association," 4th ed., text rev.). However, reports are emerging that attention deficit hyperactivity…

  18. Lisdexamfetamine in the treatment of adolescents and children with attention-deficit/hyperactivity disorder

    OpenAIRE

    Najib J

    2012-01-01

    Jadwiga Najib1–31Division of Pharmacy Practice, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, 2Department of Pharmacy, 3Department of Psychiatry, St Luke's-Roosevelt Hospital Center, New York, NY, USAAbstract: Attention-deficit/hyperactivity disorder is one of the most common neurobehavioral disorders defined by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity. Symptoms begin in childho...

  19. Clinical use of a modified release methylphenidate in the treatment of childhood attention deficit hyperactivity disorder

    OpenAIRE

    Takon Inyang

    2011-01-01

    Abstract Attention deficit hyperactivity disorder (ADHD) is the most commonly diagnosed neurobehavioural disorder in childhood, affecting over 5% of children worldwide. As well as the core symptoms of inattention, hyperactivity and impulsivity, patients often exhibit learning difficulties and impairment in social functioning. The frequency of referral is higher for boys than for girls (about 2:1), and girls are generally older at the time of referral. Pharmacological therapy is considered the...

  20. Zinc, ferritin, magnesium and copper in a group of Egyptian children with attention deficit hyperactivity disorder

    OpenAIRE

    Mahmoud Magdy M; El-Mazary Abdel-Azeem M; Maher Reham M; Saber Manal M

    2011-01-01

    Abstract Background Attention deficit hyperactivity disorder is a behavioral syndrome of childhood characterized by inattention, hyperactivity and impulsivity. There were many etiological theories showed dysfunction of some brain areas that are implicated in inhibition of responses and functions of the brain. Minerals like zinc, ferritin, magnesium and copper may play a role in the pathogenesis and therefore the treatment of this disorder. Objective This study aimed to measure levels of zinc,...

  1. Secondary attention deficit/hyperactivity disorder due to right basal ganglia injury: A case report

    OpenAIRE

    Ceylan, Mehmet Fatih; AKCA, Ömer Faruk

    2013-01-01

    Attention deficit/hyperactivity disorder (ADHD) is a frequent and commonly studied neuropsychiatric disorder in children and adolescents. The symptoms of ADHD include inattention and/or hyperactivity and impulsivity. Diagnosis of ADHD requires a persistent pattern of symptoms beginning before the age of 7 except for secondary ADHD. Secondary ADHD may occur as a consequence of childhood traumatic brain injury. A patient with secondary ADHD as a result of right basal ganglia injury is presented...

  2. The Effect of EEG Biofeedback Therapy on Motor Abilities of Children with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Elena Žiaková; Stanislava Klobucká

    2015-01-01

    Background. Currently, EEG biofeedback (Neurofeedback) is used in the rehabilitation of children with brain damage with the symptoms of attention deficit disorder, hyperactivity and impulsivity. After treatment improvements were observed not only in the control of attention and impulsivity but also in voluntary and involuntary movements. The aim of the prospective clinical study was to measure the impact of EEG biofeedback on motor abilities of children with ADHD (Attention Deficit Hyperactiv...

  3. Abnormal Distracter Processing in Adults with Attention-Deficit-Hyperactivity Disorder

    OpenAIRE

    Marzinzik, Frank; Wahl, Michael; Krüger, Doris; Gentschow, Laura; Colla, Michael; Klostermann, Fabian

    2012-01-01

    Background Subjects with Attention-Deficit Hyperactivity Disorder (ADHD) are overdistractible by stimuli out of the intended focus of attention. This control deficit could be due to primarily reduced attentional capacities or, e. g., to overshooting orienting to unexpected events. Here, we aimed at identifying disease-related abnormalities of novelty processing and, therefore, studied event-related potentials (ERP) to respective stimuli in adult ADHD patients compared to healthy subjects. Met...

  4. Prevalence of bipolar disorder in children and adolescents with attention-deficit hyperactivity disorder†

    OpenAIRE

    Hassan, Amani; Agha, Sharifah Shameem; Langley, Kate; Thapar, Anita

    2011-01-01

    Background Some research suggests that children with attention-deficit hyperactivity disorder (ADHD) have a higher than expected risk of bipolar affective disorder. No study has examined the prevalence of bipolar disorder in a UK sample of children with ADHD. Aims To examine the prevalence of bipolar disorder in children diagnosed with ADHD or hyperkinetic disorder. Method Psychopathology symptoms and diagnoses of bipolar disorder were assessed in 200 young people with ADHD (170 male, 30 fema...

  5. Functional analysis and treatment of elopement for a child with attention deficit hyperactivity disorder.

    OpenAIRE

    Kodak, Tiffany; Grow, Laura; Northup, John

    2004-01-01

    We conducted a functional analysis of elopement in an outdoor setting for a child with a diagnosis of attention deficit hyperactivity disorder. A subsequent treatment consisting of noncontingent attention and time-out was demonstrated to be effective in eliminating elopement. Modifications of functional analysis procedures associated with the occurrence of elopement in a natural setting are demonstrated.

  6. Detrimental effects of gum chewing on vigilance in children with attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Tucha, Lara; Simpson, William; Evans, Lynsay; Birrel, Laura; Sontag, Thomas A.; Lange, Klaus W.; Tucha, Oliver

    2010-01-01

    Impairments of attention are cardinal features of attention deficit hyperactivity disorder (ADHD) and can seriously affect the daily life of children with ADHD. Despite effective treatment strategies, there is a need of further treatment options that can be added to available and well established tr

  7. Does Response Variability Predict Distractibility among Adults with Attention-Deficit/Hyperactivity Disorder?

    Science.gov (United States)

    Adams, Zachary W.; Roberts, Walter M.; Milich, Richard; Fillmore, Mark T.

    2011-01-01

    Increased intraindividual variability in response time (RTSD) has been observed reliably in attention-deficit/hyperactivity disorder (ADHD) and has often been used as a measure of inattention. RTSD is assumed to reflect attentional lapses and distractibility, though evidence for the validity of this connection is lacking. We assessed whether RTSD…

  8. Self-Regulation Interventions for Children with Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Reid, Robert; Trout, Alexandra L.; Schartz, Michalla

    2005-01-01

    Current recommendations for the treatment of attention deficit/hyperactivity disorder (ADHD) call for a multimodal approach including a combination of medication, behavior modification, school accommodations, and ancillary services. One method that has been proposed as an effective and efficient means for increasing students' attention and…

  9. Written Composition Performance of Students with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Casas, Ana Miranda; Ferrer, Manuel Soriano; Fortea, Inmaculada Baixauli

    2013-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is frequently associated with learning disabilities. The present study examined the written composition of children with ADHD, which depends to a large degree on continuous self-regulation and attentional control skills for organizing information and maintaining the level of effort. Fifty children…

  10. Effect of Symptoms of Adult Attention Deficit Hyperactivity Disorder on Symptoms of Post Traumatic Stress Disorder in Korean Conscripts

    OpenAIRE

    Lee, Dong-Yun; Lee, Cheol-Soon; Park, Chul-Soo; Kim, Bong-Jo; Cha, Bo-Seok; Lee, So-Jin; Bhang, Soo Young

    2012-01-01

    Objective This study is conducted to investigate the effect of symptoms of Attention Deficit and Hyperactivity Disorder (ADHD) on symptoms of Posttraumatic Stress Disorder (PTSD) among 224 conscripts during 5 weeks of military basic training. Methods Total number of subject is 224 conscripts. We evaluated past and present symptoms of ADHD with Korean-Wender Utah rating scale (K-WURS) and Korean adult attention -deficit/hyperactivity disorder scale (K-AADHDS) and stress and symptoms of PTSD wi...

  11. Lisdexamfetamine in the treatment of adolescents and children with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Najib J

    2012-05-01

    Full Text Available Jadwiga Najib1–31Division of Pharmacy Practice, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, 2Department of Pharmacy, 3Department of Psychiatry, St Luke's-Roosevelt Hospital Center, New York, NY, USAAbstract: Attention-deficit/hyperactivity disorder is one of the most common neurobehavioral disorders defined by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity. Symptoms begin in childhood and may persist into adolescence and adulthood. Currently available pharmacological treatment options for attention-deficit/hyperactivity disorder in children and adolescents include stimulants that are efficacious and well tolerated; however, many of these preparations require multiple daily dosing and have the potential for abuse. Lisdexamfetamine dimesylate, the first prodrug stimulant, was developed to provide a longer duration of effect. It demonstrates a predictable delivery of the active drug, d-amphetamine, with low interpatient variability, and has a reduced potential for abuse. A literature search of the MEDLINE database and clinical trials register from 1995–2011, as well as relevant abstracts presented at annual professional meetings, on lisdexamfetamine dimesylate in children and adolescents were included for review. This article presents the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate for the treatment of attention-deficit/hyperactivity disorder in children and, more recently, in adolescents.Keywords: lisdexamfetamine dimesylate, prodrug stimulant, attention-deficit and hyperactivity disorders, safety, efficacy, children, adolescents

  12. Motor Profile of Children with Attention Deficit Hyperactivity Disorder, Combined Type

    Science.gov (United States)

    Goulardins, Juliana B.; Marques, Juliana C. Bilhar; Casella, Erasmo B.; Nascimento, Roseane O.; Oliveira, Jorge A.

    2013-01-01

    Objectives: The aim of this study was to assess the motor profile of children with attention deficit hyperactivity disorder (ADHD), combined type. Method: The case group consisted of 34 treatment-naive, male patients, aged 7-11 years, who had been diagnosed with ADHD, combined type, without comorbidities (except oppositional defiant disorder). The…

  13. Consequences of Co-Occurring Attention-Deficit/Hyperactivity Disorder on Children's Language Impairments

    Science.gov (United States)

    Redmond, Sean M.; Ash, Andrea C.; Hogan, Tiffany P.

    2015-01-01

    Purpose: Co-occurring attention-deficit/hyperactivity disorder (ADHD) and communication disorders represent a frequently encountered challenge for school-based practitioners. The purpose of the present study was to examine in more detail the clinical phenomenology of co-occurring ADHD and language impairments (LIs). Method: Measures of nonword…

  14. Persistence of Sleep Problems in Children with Anxiety and Attention Deficit Hyperactivity Disorders

    Science.gov (United States)

    Hansen, Berit Hjelde; Skirbekk, Benedicte; Oerbeck, Beate; Wentzel-Larsen, Tore; Kristensen, Hanne

    2013-01-01

    This study examines the persistence of sleep problems over 18 months in 76 referred children with anxiety disorders and/or attention deficit hyperactivity disorders (ADHD) and 31 nonreferred controls, and explores predictors of sleep problems at follow-up (T2) in the referred children. Diagnoses were assessed at initial assessment (T1) using the…

  15. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder

    DEFF Research Database (Denmark)

    Håvik, Bjarte; Degenhardt, Franziska A; Johansson, Stefan; Fernandes, Carla P D; Hinney, Anke; Scherag, André; Lybæk, Helle; Djurovic, Srdjan; Christoforou, Andrea; Ersland, Kari M; Giddaluru, Sudheer; O'Donovan, Michael C; Owen, Michael J; Craddock, Nick; Mühleisen, Thomas W; Mattheisen, Manuel; Schimmelmann, Benno G; Renner, Tobias; Warnke, Andreas; Herpertz-Dahlmann, Beate; Sinzig, Judith; Albayrak, Özgür; Rietschel, Marcella; Nöthen, Markus M; Bramham, Clive R; Werge, Thomas; Hebebrand, Johannes; Haavik, Jan; Andreassen, Ole A; Cichon, Sven; Steen, Vidar M; Le Hellard, Stéphanie

    2012-01-01

    that have neuro-cognitive dysfunctions: schizophrenia (SCZ), bipolar affective disorder (BP) and attention deficit/hyperactivity disorder (ADHD). We mined six genome wide association studies (GWASs) that were available publically or through collaboration; three for BP, two for SCZ and one for ADHD. We...

  16. Economic Impact of Childhood and Adult Attention-Deficit/Hyperactivity Disorder in the United States

    Science.gov (United States)

    Doshi, Jalpa A.; Hodgkins, Paul; Kahle, Jennifer; Sikirica, Vanja; Cangelosi, Michael J.; Setyawan, Juliana; Erder, M. Haim; Neumann, Peter J.

    2012-01-01

    Objective: Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent mental disorders in children in the United States and often persists into adulthood with associated symptomatology and impairments. This article comprehensively reviews studies reporting ADHD-related incremental (excess) costs for children/adolescents and…

  17. Italian Teachers' Knowledge and Perception of Attention Deficit Hyperactivity Disorder (ADHD)

    Science.gov (United States)

    Frigerio, Alessandra; Montali, Lorenzo; Marzocchi, Gian Marco

    2014-01-01

    Teachers' perceptions of attention deficit hyperactivity disorder (ADHD) can influence the diagnostic rates of the disorder and the management of children in schools. This study investigated the knowledge and perceptions of ADHD in a sample of 589 Italian primary school teachers using a self-report questionnaire that included the ADHD perceptions…

  18. Noninvasive Brain Stimulation in Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) : A Review

    NARCIS (Netherlands)

    Rubio, Belen; Boes, Aaron D; Laganiere, Simon; Rotenberg, Alexander; Jeurissen, Danique; Pascual-Leone, Alvaro

    2016-01-01

    Attention-deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in the pediatric population. The clinical management of ADHD is currently limited by a lack of reliable diagnostic biomarkers and inadequate therapy for a minority of patients who do not respond

  19. White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Cooper, Miriam; Thapar, Anita; Jones, Derek K.

    2014-01-01

    Traits of autism spectrum disorder (ASD) in children with attention-deficit/hyperactivity disorder (ADHD) have previously been found to index clinical severity. This study examined the association of ASD traits with diffusion parameters in adolescent males with ADHD (n = 17), and also compared WM microstructure relative to controls (n = 17).…

  20. Examining the Comorbidity of Language Impairment and Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Mueller, Kathryn L.; Tomblin, J. Bruce

    2012-01-01

    Language impairment (LI) and attention-deficit/hyperactivity disorder (ADHD) are 2 relatively common developmental disorders that have been shown to have high rates of co-occurrence in a number of studies, and this phenomenon is also commonplace in the experience of many clinicians. Understanding this comorbidity, therefore, is central to building…

  1. Parenting Practices and Attention-Deficit/Hyperactivity Disorder: New Findings Suggest Partial Specificity of Effects

    Science.gov (United States)

    Ellis, Brandi; Nigg, Joel

    2009-01-01

    The relation between attention deficit hyperactivity disorder (ADHD) and parenting practices is examined by assessing 182 children for ADHD and non ADHD status through parent semistructured clinical interview. Results show that maternal inconsistent discipline and paternal low involvement is associated with the disorder.

  2. Family-Based Genome-Wide Association Scan of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Mick, Eric; Todorov, Alexandre; Smalley, Susan; Hu, Xiaolan; Loo, Sandra; Todd, Richard D.; Biederman, Joseph; Byrne, Deirdre; Dechairo, Bryan; Guiney, Allan; McCracken, James; McGough, James; Nelson, Stanley F.; Reiersen, Angela M.; Wilens, Timothy E.; Wozniak, Janet; Neale, Benjamin M.; Faraone, Stephen V.

    2010-01-01

    Objective: Genes likely play a substantial role in the etiology of attention-deficit/hyperactivity disorder (ADHD). However, the genetic architecture of the disorder is unknown, and prior genome-wide association studies (GWAS) have not identified a genome-wide significant association. We have conducted a third, independent, multisite GWAS of…

  3. Effects of Self-monitoring Technique on Inattentive Behaviors of Students with Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Mirnasab, Mir Mahmoud; Bonab, Bagher Ghobari

    2011-01-01

    Beneficial effects of stimulants on core symptoms of Attention Deficit Hyperactivity Disorder (ADHD) have been reported in several studies. Behavioral interventions have also been proposed as empirically supported interventions for ADHD. Although cognitive-behavioral therapies (CBT) have been criticized for the lack of evidence-based data, some studies have indicated the positive effects of CBT techniques on children with attention deficit hyperactivity disorder (ADHD). This article reports the effects of self-monitoring technique, as a CBT technique, on inattentive behaviors of children with ADHD. PMID:22952528

  4. Effects of Self-monitoring Technique on Inattentive Behaviors of Students with Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Bagher Ghobari Bonab

    2011-06-01

    Full Text Available Beneficial effects of stimulants on core symptoms of Attention Deficit Hyperactivity Disorder (ADHD have been reported in several studies. Behavioral interventions have also been proposed as empirically supported interventions for ADHD. Although cognitive-behavioral therapies (CBT have been criticized for the lack of evidence-based data, some studies have indicated the positive effects of CBT techniques on children with attention deficit hyperactivity disorder (ADHD. This article reports the effects of self-monitoring technique, as a CBT technique, on inattentive behaviors of children with ADHD.

  5. Timing deficits in attention-deficit/hyperactivity disorder (ADHD): evidence from neurocognitive and neuroimaging studies.

    Science.gov (United States)

    Noreika, Valdas; Falter, Christine M; Rubia, Katya

    2013-01-01

    Relatively recently, neurocognitive and neuroimaging studies have indicated that individuals with attention-deficit/hyperactivity disorder (ADHD) may have deficits in a range of timing functions and their underlying neural networks. Despite this evidence, timing deficits in ADHD are still somewhat neglected in the literature and mostly omitted from reviews on ADHD. There is therefore a lack of integrative reviews on the up-to-date evidence on neurocognitive and neurofunctional deficits of timing in ADHD and their significance with respect to other behavioural and cognitive deficits. The present review provides a synthetic overview of the evidence for neurocognitive and neurofunctional deficits in ADHD in timing functions, and integrates this evidence with the cognitive neuroscience literature of the neural substrates of timing. The review demonstrates that ADHD patients are consistently impaired in three major timing domains, in motor timing, perceptual timing and temporal foresight, comprising several timeframes spanning milliseconds, seconds, minutes and longer intervals up to years. The most consistent impairments in ADHD are found in sensorimotor synchronisation, duration discrimination, reproduction and delay discounting. These neurocognitive findings of timing deficits in ADHD are furthermore supported by functional neuroimaging studies that show dysfunctions in the key inferior fronto-striato-cerebellar and fronto-parietal networks that mediate the timing functions. Although there is evidence that these timing functions are inter-correlated with other executive functions that are well established to be impaired in the disorder, in particular working memory, attention, and to a lesser degree inhibitory control, the key timing deficits appear to survive when these functions are controlled for, suggesting independent cognitive deficits in the temporal domain. There is furthermore strong evidence for an association between timing deficits and behavioural

  6. A Genetic Study of Attention Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder and Reading Disability: Aetiological Overlaps and Implications

    Science.gov (United States)

    Martin, Neilson C.; Levy, Florence; Pieka, Jan; Hay, David A.

    2006-01-01

    Attention Deficit Hyperactivity Disorder (ADHD) commonly co-occurs with Oppositional Defiant Disorder, Conduct Disorder and Reading Disability. Twin studies are an important approach to understanding and modelling potential causes of such comorbidity. Univariate and bivariate genetic models were fitted to maternal report data from 2040 families of…

  7. Conditioned Inhibition in a Rodent Model of Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Green, John T.; Chess, Amy C.; Conquest, Cynthia J.; Yegla, Brittney A.

    2011-01-01

    A deficit in inhibition may underlie some of the symptoms of Attention-deficit/hyperactivity disorder (ADHD), particularly impulsivity. However, the data on inhibitory deficits in children with ADHD are mixed. Moreover, there has been little characterization of inhibitory processes in animal models of ADHD. Pavlov’s conditioned inhibition procedure allows a direct assessment of the inhibitory status of a stimulus via summation and retardation tests. Therefore, in the current study we examined...

  8. Emotional bias of cognitive control in adults with childhood attention-deficit/hyperactivity disorder

    OpenAIRE

    Schulz, Kurt P.; Bédard, Anne-Claude V.; Jin Fan; Clerkin, Suzanne M.; Danai Dima; Newcorn, Jeffrey H.; Halperin, Jeffrey M.

    2014-01-01

    Affect recognition deficits found in individuals with attention-deficit/hyperactivity disorder (ADHD) across the lifespan may bias the development of cognitive control processes implicated in the pathophysiology of the disorder. This study aimed to determine the mechanism through which facial expressions influence cognitive control in young adults diagnosed with ADHD in childhood. Fourteen probands with childhood ADHD and 14 comparison subjects with no history of ADHD were scanned with functi...

  9. Lead and PCBs as Risk Factors for Attention Deficit/Hyperactivity Disorder

    OpenAIRE

    Eubig, Paul A.; Aguiar, Andréa; Schantz, Susan L

    2010-01-01

    Objectives Attention deficit/hyperactivity disorder (ADHD) is the most frequently diagnosed neurobehavioral disorder of childhood, yet its etiology is not well understood. In this review we present evidence that environmental chemicals, particularly polychlorinated biphenyls (PCBs) and lead, are associated with deficits in many neurobehavioral functions that are also impaired in ADHD. Data sources Human and animal studies of developmental PCB or lead exposures that assessed specific functiona...

  10. Differential motor alterations in children with three types of attention deficit hyperactivity disorder

    OpenAIRE

    Adrián Poblano; Belinda Luna; César Reynoso

    2014-01-01

    Objective To determine frequency of motor alterations in children with attention deficit hyperactivity disorder (ADHD). Method We evaluated 19 children aged 7-12 years with ADHD classified in three sub-types: Combined (ADHD-C), with Inattention (ADHD-I), and with Hyperactivity (ADHD-H). Controls were age- and gender matched healthy children. We utilized Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) for measuring motor skills. Results We observed differences between children with A...

  11. The Latent Structure of Attention Deficit/Hyperactivity Disorder in an Adult Sample

    OpenAIRE

    Marcus, David K.; Norris, Alyssa L.; Coccaro, Emil F.

    2012-01-01

    The vast majority of studies that have examined the latent structure of attention deficit/hyperactivity disorder (ADHD) in children and adolescents have concluded that ADHD has a dimensional latent structure. In other words, ADHD symptomatology exists along a continuum and there is no natural boundary or qualitative distinction (i.e., taxon) separating youth with ADHD from those with subclinical inattention or hyperactivity/impulsivity problems. Although adult ADHD appears to be less prevalen...

  12. Executive Functioning Differences between Adults with Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder in Initiation, Planning and Strategy Formation

    Science.gov (United States)

    Bramham, Jessica; Ambery, Fiona; Young, Susan; Morris, Robin; Russell, Ailsa; Xenitidis, Kiriakos; Asherson, Philip; Murphy, Declan

    2009-01-01

    Executive functioning deficits characterize the neuropsychological profiles of the childhood neurodevelopmental disorders of attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD). This study sought to determine whether similar impairments exist in adults with ADHD (N = 53) and ASD (N = 45) in comparison with a…

  13. Mindfulness Meditation Improves Mood, Quality of Life, and Attention in Adults with Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Viviane Freire Bueno

    2015-01-01

    Full Text Available Objective. Adults with attention deficit hyperactivity disorder (ADHD display affective problems and impaired attention. Mood in ADHD can be improved by mindful awareness practices (MAP, but results are mixed regarding the enhancement of attentional performance. Here we evaluated MAP-induced changes in quality of life (QoL, mood, and attention in adult ADHD patients and controls using more measures of attention than prior studies. Methods. Twenty-one ADHD patients and 8 healthy controls underwent 8 weekly MAP sessions; 22 similar patients and 9 controls did not undergo the intervention. Mood and QoL were assessed using validated questionnaires, and attention was evaluated using the Attentional Network Test (ANT and the Conners Continuous Performance Test (CPT II, before and after intervention. Results. MAP enhanced sustained attention (ANT and detectability (CPT II and improved mood and QoL of patients and controls. Conclusion. MAP is a complementary intervention that improves affect and attention of adults with ADHD and controls.

  14. Effects of stimulant medication on the lateralisation of line bisection judgements of children with attention deficit hyperactivity disorder

    OpenAIRE

    Sheppard, D; Bradshaw, J. (Jonathan); MATTINGLEY, J; Lee, P

    1999-01-01

    OBJECTIVES—Deficits in the maintenance of attention may underlie problems in attention deficit hyperactivity disorder (ADHD). Children with ADHD also show asymmetric attention deficits in traditional lateralisation and visuospatial orienting tasks, suggesting right hemispheric (and left hemispace) attentional disturbance. This study aimed to examine the lateralisation of selective attention in ADHD; specifically, the effect of a moving, random dot background, and stimulan...

  15. Assessing Self-Control Training in Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Bloh, Christopher

    2009-01-01

    This study examined the use of a progressive delay procedure with and without a concurrent activity to teach self-control to children with attention deficit hyperactivity disorder. Three participants were initially required to wait progressively longer periods of time for access to preferred edible reinforcers. After demonstrating this…

  16. Clonidine for Attention-Deficit/Hyperactivity Disorder: II. ECG Changes and Adverse Events Analysis

    Science.gov (United States)

    Daviss, W. Burleson; Patel, Nick C.; Robb, Adelaide S.; McDermott, Michael P.; Bukstein, Oscar G.; Pelham, William E., Jr.; Palumbo, Donna; Harris, Peter; Sallee, Floyd R.

    2008-01-01

    A study to examine the safety and tolerance of clonidine, alone or with methylphenidate as a form of treatment in children with attention-deficit/hyperactivity disorders (ADHD) is conducted. Results conclude that clonidine used alone or in combination with methylphenidate were safe and well tolerated in children with ADHD.

  17. Evidence-Based Psychosocial Treatments for Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Pelham, William E., Jr.; Fabiano, Gregory A.

    2008-01-01

    Pelham, Wheeler, and Chronis (1998) reviewed the treatment literature on attention-deficit/hyperactivity disorder (ADHD) and concluded behavioral parent training (BPT) and behavioral classroom management (BCM) were well-established treatments for children with ADHD. This review updates and extends the finding of the prior review. Studies conducted…

  18. The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-Year Follow-Up

    Science.gov (United States)

    Riddle, Mark A.; Yershova, Kseniya; Lazzaretto, Deborah; Paykina, Natalya; Yenokyan, Gayane; Greenhill, Laurence; Abikoff, Howard; Vitiello, Benedetto; Wigal, Tim; McCracken, James T.; Kollins, Scott H.; Murray, Desiree W.; Wigal, Sharon; Kastelic, Elizabeth; McGough, James J.; dosReis, Susan; Bauzo-Rosario, Audrey; Stehli, Annamarie; Posner, Kelly

    2013-01-01

    Objective: To describe the clinical course of attention-deficit/hyperactivity disorder (ADHD) symptom severity and diagnosis from ages 3 to 5 up to 9 to 12 years during a 6-year follow-up after the original Preschool ADHD Treatment Study (PATS). Method: A total of 207 participants (75% male) from the original PATS, assessed at baseline (mean age,…

  19. Effects of a Teacher Training Programme on Symptoms of Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Froelich, Jan; Breuer, Dieter; Doepfner, Manfred; Amonn, Frauke

    2012-01-01

    A substantial lack of effective school based interventions especially in the natural setting exists in the treatment of Attention Deficit Hyperactivity Disorder. We performed a 18-week teacher training programme in a public elementary school with 378 pupils in 16 classes. After completing a screening assessment for symptoms related to ADHD and to…

  20. Clonidine for Attention-Deficit/Hyperactivity Disorder: Efficacy and Tolerability Outcomes

    Science.gov (United States)

    Palumbo, Donna R.; Sallee, Floyd R.; Pelham, William E., Jr; Bukstein, Oscar G.; Daviss, W. Burleson; McDermott, Michael P.

    2008-01-01

    A study to examine the effectiveness and tolerance of clonidine alone or in combination with methylphenidate as a mode of treatment of attention-deficit/hyperactivity disorders is conducted. Results indicate methylphenidate as the most effective in treatment as compared to clonidine, which was well tolerated.

  1. The Effect of Acupressure for Moderating Behavior of Attention-Deficit/Hyperactivity Disorder Adolescents.

    Science.gov (United States)

    Johnson, Lynn; Sinnott, Jan

    This study examined the effects of an acupressure intervention with two adolescents previously diagnosed with attention deficit hyperactivity disorder (ADHD). An inventory based on standard criteria for diagnosing ADHD was completed by each student, their parents, case workers, and teachers both before and after the intervention. The intervention…

  2. Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Neale, Benjamin M.; Medland, Sarah E.; Ripke, Stephan; Asherson, Philip; Franke, Barbara; Lesch, Klaus-Peter; Faraone, Stephen V.; Nguyen, Thuy Trang; Schafer, Helmut; Holmans, Peter; Daly, Mark; Steinhausen, Hans-Christoph; Freitag, Christine; Reif, Andreas; Renner, Tobias J.; Romanos, Marcel; Romanos, Jasmin; Walitza, Susanne; Warnke, Andreas; Meyer, Jobst; Palmason, Haukur; Buitelaar, Jan; Vasquez, Alejandro Arias; Lambregts-Rommelse, Nanda; Gill, Michael; Anney, Richard J. L.; Langely, Kate; O'Donovan, Michael; Williams, Nigel; Owen, Michael; Thapar, Anita; Kent, Lindsey; Sergeant, Joseph; Roeyers, Herbert; Mick, Eric; Biederman, Joseph; Doyle, Alysa; Smalley, Susan; Loo, Sandra; Hakonarson, Hakon; Elia, Josephine; Todorov, Alexandre; Miranda, Ana; Mulas, Fernando; Ebstein, Richard P.; Rothenberger, Aribert; Banaschewski, Tobias; Oades, Robert D.; Sonuga-Barke, Edmund; McGough, James; Nisenbaum, Laura; Middleton, Frank; Hu, Xiaolan; Nelson, Stan

    2010-01-01

    Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of…

  3. Altered White Matter Microstructure in Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Nagel, Bonnie J.; Bathula, Deepti; Herting, Megan; Schmitt, Colleen; Kroenke, Christopher D.; Fair, Damien; Nigg, Joel T.

    2011-01-01

    Objective: Identification of biomarkers is a priority for attention-deficit/hyperactivity disorder (ADHD). Studies have documented macrostructural brain alterations in ADHD, but few have examined white matter microstructure, particularly in preadolescent children. Given dramatic white matter maturation across childhood, microstructural differences…

  4. White Matter Microstructure in Subjects with Attention-Deficit/Hyperactivity Disorder and Their Siblings

    Science.gov (United States)

    Lawrence, Katherine E.; Levitt, Jennifer G.; Loo, Sandra K.; Ly, Ronald; Yee, Victor; O'Neill, Joseph; Alger, Jeffry; Narr, Katherine L.

    2013-01-01

    Objective: Previous voxel-based and regions-of-interest (ROI)-based diffusion tensor imaging (DTI) studies have found above-normal mean diffusivity (MD) and below-normal fractional anisotropy (FA) in subjects with attention-deficit/hyperactivity disorder (ADHD). However, findings remain mixed, and few studies have examined the contribution of ADHD…

  5. Stimulus-Dependent Dopamine Release in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Sikstrom, Sverker; Soderlund, Goran

    2007-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is related to an attenuated and dysfunctional dopamine system. Normally, a high extracellular dopamine level yields a tonic dopaminergic input that down-regulates stimuli-evoked phasic dopamine responses through autoreceptors. Abnormally low tonic extracellular dopamine in ADHD up-regulates the…

  6. An Evaluation of Three Time-Out Procedures for Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Fabiano, Gregory A.; Pelham, William E.; Manos, Michael J.; Gnagy, Elizabeth M.; Chronis, Andrea M.; Onyango, Adia N.; Lopez-Williams, Andy; Burrows-MacLean, Lisa; Coles, Erika K.; Meichenbaum, David L.; Caserta, Donald A.; Swain, Sara

    2004-01-01

    Behavior modification is an evidence-based treatment for children with attention-deficit/hyperactivity disorder (ADHD). Time-out from positive reinforcement is one behavior-modification procedure commonly recommended to manage disruptive or noncompliant behavior. This investigation examined the effects of time-out on children's behavior within the…

  7. A Coaching Intervention for College Students with Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Swartz, Stacy L.; Prevatt, Frances; Proctor, Briley E.

    2005-01-01

    In this article we describe coaching as an intervention for college students with attention deficit/hyperactivity disorder (ADHD). Coaching college students with ADHD empowers individuals to organize and execute their responsibilities, both in academia and in everyday life. With the assistance of a coach, individuals with ADHD can create structure…

  8. Twin study on transplacental-acquired antibodies and attention deficit/hyperactivity disorder - A pilot study

    DEFF Research Database (Denmark)

    Bilenberg, Niels; Hougaard, David; Norgaard-Pedersen, Bent;

    2011-01-01

    OBJECTIVE: We hypothesize that maternal transplacentally acquired antibodies may cause Attention Deficit/Hyperactivity Disorder (ADHD) symptoms years after birth, and tested the hypothesis in twins discordant for ADHD symptoms. METHOD: In a pre-screened sample of 7793 same sex twin pair's (4...

  9. Depression and Anxiety as Possible Mediators of the Association between Smoking and Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Grunau, Gilat L.; Ratner, Pamela A.; Hossain, Shahadut; Johnson, Joy L.

    2010-01-01

    The objective of this study was to investigate the association between depression and anxiety and adolescents' smoking status, and to determine whether depression or anxiety mediate the association between Attention Deficit Hyperactivity Disorder (ADHD) and smoking. A cross-sectional survey of tobacco use was conducted in regional school districts…

  10. Predictors of Attention-Deficit/Hyperactivity Disorder within 6 Months after Pediatric Traumatic Brain Injury

    Science.gov (United States)

    Max, Jeffrey E.; Schachar, Russell J.; Levin, Harvey S.; Ewing-Cobbs, Linda; Chapman, Sandra B.; Dennis, Maureen; Saunders, Ann; Landis, Julie

    2005-01-01

    Objective: To assess the phenomenology and predictive factors of attention-deficit/hyperactivity disorder (ADHD) after traumatic brain injury (TBI), also called secondary ADHD (SADHD). Method: Children without preinjury ADHD 5-14 years old with TBI from consecutive admissions (n = 143) to five trauma centers were observed prospectively for 6…

  11. The Developmental Trajectories of Executive Function of Children and Adolescents with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Qian, Ying; Shuai, Lan; Chan, Raymond C. K.; Qian, Qiu-Jin; Wang, Yufeng

    2013-01-01

    This study examined the developmental trajectories of executive function (EF) of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) in Han Chinese. Five hundred and fifteen children and adolescents with ADHD and 249 healthy controls took part in this study. All of them were administered four EF tests capturing…

  12. Electrophysiological Evidence of Atypical Motivation and Reward Processing in Children with Attention-Deficit Hyperactivity Disorder

    Science.gov (United States)

    Holroyd, Clay B.; Baker, Travis E.; Kerns, Kimberly A.; Muller, Ulrich

    2008-01-01

    Behavioral and neurophysiological evidence suggest that attention-deficit hyperactivity disorder (ADHD) is characterized by the impact of abnormal reward prediction error signals carried by the midbrain dopamine system on frontal brain areas that implement cognitive control. To investigate this issue, we recorded the event-related brain potential…

  13. Teaching Tommy: A Second-Grader with Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Fachin, Katharina

    1996-01-01

    Recounts a second-grade teacher's efforts to help a rough-and-tumble boy diagnosed with ADHD (attention deficit hyperactivity disorder). After comprehensive behavioral and academic programs (including token rewards, peer tutoring, resource room activities, an inclass aide) failed to stabilize Tommy's behavior, Ritalin was (successfully) prescribed…

  14. Countering the Attention Deficit Hyperactivity Disorder Epidemic: A Question of Ethics?

    Science.gov (United States)

    Graham, Linda J.

    2007-01-01

    Recently in Australia, another media skirmish erupted over the problem currently called "Attention Deficit Hyperactivity Disorder". This particular event was precipitated by the comments of a respected District Court judge. His claim that doctors are creating a generation of violent juvenile offenders by prescribing Ritalin to young children…

  15. Characteristics of College Students with Attention-Deficit Hyperactivity Disorder Symptoms Who Misuse Their Medications

    Science.gov (United States)

    Jardin, Bianca; Looby, Alison; Earleywine, Mitch

    2011-01-01

    Objective: The purpose of the current investigation is to examine the characteristics of college students with attention-deficit hyperactivity disorder symptoms who misuse their prescribed psychostimulant medications. Methods and Participants: Forty-three undergraduate students with a prescription for Ritalin or Adderall completed structured…

  16. A Candidate Gene Analysis of Methylphenidate Response in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    McGough, James J.; McCracken, James T.; Loo, Sandra K.; Manganiello, Marc; Leung, Michael C.; Tietjens, Jeremy R.; Trinh, Thao; Baweja, Shilpa; Suddath, Robert; Smalley, Susan L.; Hellemann, Gerhard; Sugar, Catherine A.

    2009-01-01

    Objective: This study examines the potential role of candidate genes in moderating treatment effects of methylphenidate (MPH) in attention-deficit/hyperactivity disorder (ADHD). Method: Eighty-two subjects with ADHD aged 6 to 17 years participated in a prospective, double-blind, placebo-controlled, multiple-dose, crossover titration trial of…

  17. Revisiting the Role of the Prefrontal Cortex in the Pathophysiology of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Halperin, Jeffrey M.; Schulz, Kurt P.

    2006-01-01

    Most neural models for the pathophysiology of attention-deficit/hyperactivity disorder (ADHD) have centered on the prefrontal cortex and its interconnections with the striatum and other subcortical structures. However, research only partially supports these models, and they do not correspond with the development of the prefrontal cortex and its…

  18. Latent Class Subtyping of Attention-Deficit/Hyperactivity Disorder and Comorbid Conditions

    Science.gov (United States)

    Acosta, Maria T.; Castellanos, F. Xavier; Bolton, Kelly L.; Balog, Joan Z.; Eagen, Patricia; Nee, Linda; Jones, Janet; Palacio, Luis; Sarampote, Christopher; Russell, Heather F.; Berg, Kate; Arcos-Burgos, Mauricio; Muenke, Maximilian

    2008-01-01

    The study attempts to carry out latent class analysis (LCA) in a sample of 1010 individuals, some with Attention-Deficit/Hyperactivity disorder (ADHD) and others normal. Results indicate that LCA can feasibly allow the combination of externalizing and internalizing symptoms for future tests regarding specific genetic risk factors.

  19. Attention-Deficit/hyperactivity Disorder and Comorbidities in 18 Paisa Colombian Multigenerational Families.

    Science.gov (United States)

    Palacio, Juan D.; Castellanos, F. Xavier; Pineda, David A.; Lopera, Francisco; Arcos-Burgos, Mauricio; Quiroz, Yakeel T.; Henao, Gloria C.; Puerta, Isabel C.; Ramirez, Dora L.; Rapoport, Judith L.; Bailey-Wilson, Joan; Berg, Kate; Muenke, Maximilian

    2004-01-01

    Objective: Eighteen extended multigenerational families were recruited from the genetically isolated Paisa community in Colombia to conduct genetic studies of attention-deficit/hyperactivity disorder (ADHD). This report describes the inclusion strategy and clinical features of participants to facilitate comparisons with other data sets. Method:…

  20. Symptoms of Attention Deficit Hyperactivity Disorder in Children and Adults with Intellectual Disability: A Review

    Science.gov (United States)

    Reilly, Colin; Holland, Niamh

    2011-01-01

    Background: Despite a reported excess of attention deficit hyperactivity disorder (ADHD) symptoms in individuals with intellectual disability, it has been argued that ADHD symptoms have been under diagnosed and inadequately treated in individuals with intellectual disability. Materials and methods: Published studies focussing on the level of ADHD…

  1. Ethnic Disparities in Special Education Labeling among Children with Attention- Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Mandell, David S.; Davis, Jasmine K.; Bevans, Katherine; Guevara, James P.

    2008-01-01

    The authors examined disparities in special education labeling among children diagnosed with attention-deficit/hyperactivity disorder (ADHD) by merging calendar year 2002 special education records and Medicaid mental health claims for 4,852 children who had been diagnosed with ADHD in Philadelphia, Pennsylvania. Thirty-eight percent were receiving…

  2. Does Attention-Deficit-Hyperactivity Disorder Exacerbate Executive Dysfunction in Children with Neurofibromatosis Type 1?

    Science.gov (United States)

    Payne, Jonathan M.; Arnold, Shelley S.; Pride, Natalie A.; North, Kathryn N.

    2012-01-01

    Aim: Although approximately 40% of children with neurofibromatosis type 1 (NF1) meet diagnostic criteria for attention-deficit-hyperactivity disorder (ADHD), the impact of ADHD on the executive functioning of children with NF1 is not understood. We investigated whether spatial working memory and response inhibition are impaired in children with…

  3. Examining Relationships between Executive Functioning and Delay Aversion in Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Karalunas, Sarah L.; Huang-Pollock, Cynthia L.

    2011-01-01

    Although motivation and cognition are often examined separately, recent theory suggests that a delay-averse motivational style may negatively impact development of executive functions (EFs), such as working memory (WM) and response inhibition (RI) for children with Attention Deficit Hyperactivity Disorder (ADHD; Sonuga-Barke, 2002). This model…

  4. Cortical Gray Matter in Attention-Deficit/Hyperactivity Disorder: A Structural Magnetic Resonance Imaging Study

    Science.gov (United States)

    Batty, Martin J.; Liddle, Elizabeth B.; Pitiot, Alain; Toro, Roberto; Groom, Madeleine J.; Scerif, Gaia; Liotti, Mario; Liddle, Peter F.; Paus, Tomas; Hollis, Chris

    2010-01-01

    Objective: Previous studies have shown smaller brain volume and less gray matter in children with attention-deficit/hyperactivity disorder (ADHD). Relatively few morphological studies have examined structures thought to subserve inhibitory control, one of the diagnostic features of ADHD. We examined one such region, the pars opercularis,…

  5. Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Zhou, Kaixin; Dempfle, Astrid; Arcos-Burgos, Mauricio; Bakker, Steven C; Banaschewski, Tobias; Biederman, Joseph; Buitelaar, Jan; Castellanos, F Xavier; Doyle, Alysa; Ebstein, Richard P; Ekholm, Jenny; Forabosco, Paola; Franke, Barbara; Freitag, Christine; Friedel, Susann; Gill, Michael; Hebebrand, Johannes; Hinney, Anke; Jacob, Christian; Lesch, Klaus Peter; Loo, Sandra K; Lopera, Francisco; McCracken, James T; McGough, James J; Meyer, Jobst; Mick, Eric; Miranda, Ana; Muenke, Maximilian; Mulas, Fernando; Nelson, Stanley F; Nguyen, T Trang; Oades, Robert D; Ogdie, Matthew N; Palacio, Juan David; Pineda, David; Reif, Andreas; Renner, Tobias J; Roeyers, Herbert; Romanos, Marcel; Rothenberger, Aribert; Schäfer, Helmut; Sergeant, Joseph; Sinke, Richard J; Smalley, Susan L; Sonuga-Barke, Edmund; Steinhausen, Hans-Christoph; van der Meulen, Emma; Walitza, Susanne; Warnke, Andreas; Lewis, Cathryn M; Faraone, Stephen V; Asherson, Philip

    2008-01-01

    Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, th

  6. The Efficacy of Notetaking to Improve Behavior and Comprehension of Adolescents with Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Evans, Steven W.; And Others

    1995-01-01

    Two studies evaluated a notetaking intervention targeting the passive learning style and disruptive behaviors exhibited by adolescents with attention deficit hyperactivity disorder. Thirty teens in a summer program were able to learn notetaking strategies using a modification of the Directed Notetaking Activity training method and showed…

  7. Cardiovascular Risk of Stimulant Treatment in Pediatric Attention-Deficit/Hyperactivity Disorder: Update and Clinical Recommendations

    Science.gov (United States)

    Hammerness, Paul G.; Perrin, James M.; Shelley-Abrahamson, Rachel; Wilens, Timothy E.

    2011-01-01

    Objective: This review provides an update on the cardiovascular impact of therapeutic stimulant-class medication for children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Method: Relevant clinical literature was ascertained using PubMed searches limited to human studies and the English language as of May 2011. Current…

  8. Study of Level of Stress in the Parents of Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Sethi, Sujata; Gandhi, Raghu; Anand, Vidhu

    2012-01-01

    Background: Parents who have children with attention-deficit hyperactivity disorder (ADHD) often experience high level of stress related to caring for their children. But not much research has been conducted in this area in India. This study aimed to assess the stress of parenting children with ADHD. Methods: This is a clinic based comparative…

  9. Epilepsy and attention deficit hyperactivity disorder : Is methylphenidate safe and effective?

    NARCIS (Netherlands)

    GrossTsur, [No Value; vanderMeere, J; Joseph, A; Shalev, RS

    1997-01-01

    Objective: To study the safety and efficacy of methylphenidate in children with the dual diagnosis of epilepsy and attention deficit hyperactivity disorder (ADHD). Study design: Thirty children, aged 6.4 to 16.4 years, with epilepsy and ADHD were studied during a 4-month period. During the initial 2

  10. Pharmacogenetic Predictors of Methylphenidate Dose-Response in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Froehlich, Tanya E.; Epstein, Jeffery N.; Nick, Todd G.; Melguizo Castro, Maria S.; Stein, Mark A.; Brinkman, William B.; Graham, Amanda J.; Langberg, Joshua M.; Kahn, Robert S.

    2011-01-01

    Objective: Because of significant individual variability in attention-deficit/hyperactivity disorder (ADHD) medication response, there is increasing interest in identifying genetic predictors of treatment effects. This study examined the role of four catecholamine-related candidate genes in moderating methylphenidate (MPH) dose-response. Method:…

  11. Epilepsy and attention deficit hyperactivity disorder : Is methylphenidate safe and effective? (vol 130, pg 40, 1997)

    NARCIS (Netherlands)

    GrossTsur, [No Value; Manor, O; VanderMeere, J; Joseph, A; Shalev, RS

    1997-01-01

    Objective: To study the safety and efficacy of methylphenidate in children with the dual diagnosis of epilepsy and attention deficit hyperactivity disorder (ADHD). Study design: Thirty children, aged 6.4 to 16.4 years, with epilepsy and ADHD were studied during a 4-month period. During the initial 2

  12. Consultation-Based Academic Intervention for Children with Attention Deficit Hyperactivity Disorder: School Functioning Outcomes

    Science.gov (United States)

    Jitendra, Asha K.; DuPaul, George J.; Volpe, Robert J.; Tresco, Katy E.; Junod, Rosemary E. Vile; Lutz, J. Gary; Cleary, Kristi S.; Flammer-Rivera, Lizette M.; Manella, Mark C.

    2007-01-01

    This study evaluated the effectiveness of two consultation-based models for designing academic interventions to enhance the educational functioning of children with attention deficit hyperactivity disorder. Children (N = 167) meeting "Diagnostic and Statistical Manual" (4th ed.--text revision; American Psychiatric Association, 2000) criteria for…

  13. Use of the Differential Ability Scales for Children with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Reddy, Linda A.; Braunstein, Dania J.; Dumont, Ronald

    2008-01-01

    The validity of the Differential Ability Scales (DAS) was assessed among children with attention-deficit/hyperactivity disorder (ADHD) and a matched control sample. The sample included 45 children with ADHD (69% with comorbidity) and 45 controls matched by age, gender, ethnicity, and parental educational level. Multivariate analysis of variance…

  14. Individuals with a Gifted/Attention Deficit/Hyperactivity Disorder Diagnosis

    Science.gov (United States)

    Lee, Kelly M.; Olenchak, F. Richard

    2015-01-01

    This paper reviews the current literature on twice-exceptional students who are dual diagnosed as having giftedness and attention deficit/hyperactivity disorder (ADHD). This area of research is warranted because giftedness and ADHD present similarly but have different ramifications for performance and outcomes. In addition, research inquiry and…

  15. The relation between procrastination and symptoms of attention-deficit hyperactivity disorder (ADHD) in undergraduate students

    NARCIS (Netherlands)

    Niermann, H.C.M.; Scheres, A.P.J.

    2014-01-01

    Procrastination is defined as the tendency to delay activities that have to be completed before a deadline. It is often part of psychotherapies for adults with attention-deficit hyperactivity disorder (ADHD). However, procrastination is officially not acknowledged as an ADHD-related symptom. Therefo

  16. Evidence-Based Assessment of Attention Deficit Hyperactivity Disorder in Children and Adolescents

    Science.gov (United States)

    Pelham, Jr., William E.; Fabiano, Gregory A.; Massetti, Greta M.

    2005-01-01

    This article examines evidence-based assessment practices for attention deficit hyperactivity disorder (ADHD). The nature, symptoms, associated features, and comorbidity of ADHD are briefly described, followed by a selective review of the literature on the reliability and validity of ADHD assessment methods. It is concluded that symptom rating…

  17. Adults with Attention-Deficit/ Hyperactivity Disorder: Assessment and Treatment Strategies

    Science.gov (United States)

    Wadsworth, John S.; Harper, Dennis C.

    2007-01-01

    Attention-deficit/hyperactivity disorder (ADHD) among adults is characterized by inattentiveness and impulsivity. This article provides counselors with information about the etiology, assessment, and treatment of adult ADHD. The identification of the genetic and neurological features of ADHD has led to improvements in evaluation and treatment.…

  18. Attention Deficit Hyperactivity Disorder among Asian American Families: Challenges in Assessment and Treatment

    Science.gov (United States)

    Pham, Andy V.

    2013-01-01

    Studies addressing assessment and treatment of attention deficit hyperactivity disorder (ADHD) have primarily been focused on Caucasian populations, although a growing number of studies have included ethnic minority populations, particularly Hispanic and African American children. Findings regarding the relationship between ADHD diagnosis and race…

  19. Associations between Maternal Attention-Deficit/Hyperactivity Disorder Symptoms and Parenting

    Science.gov (United States)

    Chronis-Tuscano, Andrea; Raggi, Veronica L.; Clarke, Tana L.; Rooney, Mary E.; Diaz, Yamalis; Pian, Jessica

    2008-01-01

    Mothers of children with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for an ADHD diagnosis themselves, which is likely associated with impairments in parenting. The present study utilized a multi-method assessment of maternal ADHD and parenting to examine the extent to which maternal ADHD symptoms are associated with…

  20. The Importance of Friendship for Youth with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Mikami, Amori Yee

    2010-01-01

    It is well-established that youth with attention-deficit/hyperactivity disorder (ADHD) are often peer-rejected and rated by parents, teachers, and observers to have poor social skills, when compared to typically developing peers. Significantly less research, however, has been devoted to the experiences youth with ADHD have in their close…

  1. Developmental Phenotypes and Causal Pathways in Attention Deficit/Hyperactivity Disorder: Potential Targets for Early Intervention?

    Science.gov (United States)

    Sonuga-Barke, Edmund J. S.; Halperin, Jeffrey M.

    2010-01-01

    Early intervention approaches have rarely been implemented for the prevention of attention deficit/hyperactivity disorder (ADHD). In this paper we explore whether such an approach may represent an important new direction for therapeutic innovation. We propose that such an approach is most likely to be of value when grounded in and informed by…

  2. School Interventions for Attention Deficit Hyperactivity Disorder: Where to from Here?

    Science.gov (United States)

    Barkley, Russell A.

    2007-01-01

    In this article, the author considers some issues concerning future research into school-based assessment and management of attention deficit hyperactivity disorder (ADHD). He focuses on a few issues of some relevance to school interventions for children and teens with ADHD. He features three articles that found that less intensive interventions…

  3. Perceived Effectiveness of Classroom Management Interventions with Attention Deficit/Hyperactivity Disorder (ADHD) Students

    Science.gov (United States)

    Conforti, Darlene

    2012-01-01

    Many teachers are concerned about their ability to work effectively with students who have attention deficit/ hyperactivity disorder (ADHD). The purpose of this quantitative, descriptive study was to determine the perceived efficacy of common interventions used to address negative ADHD behaviors in the elementary and middle school classrooms. The…

  4. Interaction of Parenting Styles and Attention Deficit Hyperactivity Disorder in Iranian Parents.

    Science.gov (United States)

    Alizadeh, Hamid; Andries, Caroline

    2002-01-01

    Examines the relationships between parenting styles and attention deficit hyperactivity disorder (ADHD), utilizing a sample of Iranian parents of children with and without ADHD. Results indicate significant relationships between ADHD and parenting styles. There is a negative relationship between having an ADHD child and applying authoritative…

  5. Efficacy of Teacher In-Service Training for Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Jones, Heather A.; Chronis-Tuscano, Andrea

    2008-01-01

    Children with attention-deficit/hyperactivity disorder (ADHD) evidence many problems in the classroom. Teacher in-service training is routinely used to inform school professionals about a number of special topics; however, the efficacy of such in-service training for ADHD has not been established. The present study examined the efficacy of brief…

  6. Cognitive Behavior Therapy for College Students with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Ramsay, J. Russell; Rostain, Anthony L.

    2006-01-01

    Attention-Deficit/Hyperactivity Disorder (ADHD) is a developmental syndrome that persists into adulthood for the majority of children with ADHD. Other individuals may not experience the full negative effects of undiagnosed ADHD until they face the demands of adult life. College counseling centers in particular are seeing a rise in the number of…

  7. Medication and School Intervention for Elementary Students with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Morisoli, Kelly; McLaughlin, T. F.

    2004-01-01

    Attention Deficit Hyperactivity disorder (ADHD) affects increasing numbers of children in every country around the world. Children who are diagnosed with ADHD are constantly having difficulties in the classroom environment. There are various medication therapies and evidence based procedures (EBP) which teachers can employ to further assist…

  8. Teacher Knowledge of Attention Deficit Hyperactivity Disorder among Middle School Students in South Texas

    Science.gov (United States)

    Guerra, Fred R., Jr.; Brown, Michelle S.

    2012-01-01

    This quantitative study examined the knowledge levels middle school teachers in South Texas have in relation to attention deficit hyperactivity disorder (ADHD). The study specifically compared teacher knowledge levels among three specific ADHD knowledge areas: (a) general knowledge of ADHD, (b) knowledge of symptoms/diagnosis of ADHD, and (c)…

  9. Academic Interventions for Students with Attention-Deficit/Hyperactivity Disorder: A Review of the Literature.

    Science.gov (United States)

    DuPaul, George J.; Eckert, Tanya L.

    1998-01-01

    Reviews empirical studies that have reported the effects of academic interventions with students with attention-deficit hyperactivity disorder (ADHD). Reviews intervention in the general categories of peer tutoring, computer-assisted instruction, task and instructional modifications, and strategy training. Finds peer tutoring and task…

  10. Attention Deficit/Hyperactivity Disorder: Perspectives of Participants in the Identification and Treatment Process.

    Science.gov (United States)

    Davison, Judy C.

    2001-01-01

    Questions the rising incidence of Attention Deficit/Hyperactivity Disorder (AD/HD) diagnosis in the United States. Suggests that AD/HD is a socially constructed phenomenon rather than biologically based. Urges educators, medical personnel, and parents to take a holistic view of each child, with a serious examination of the wide range of causation…

  11. Asthma and Attention-Deficit/Hyperactivity Disorder: A Nationwide Population-Based Prospective Cohort Study

    Science.gov (United States)

    Chen, Mu-Hong; Su, Tung-Ping; Chen, Ying-Sheue; Hsu, Ju-Wei; Huang, Kai-Lin; Chang, Wen-Han; Chen, Tzeng-Ji; Bai, Ya-Mei

    2013-01-01

    Background: Previous cross-sectional studies have suggested an association between asthma and attention-deficit/hyperactivity disorder (ADHD), but the temporal relationship was not determined. Using a nationwide population-based prospective case-control cohort study (1:4, age-/gender-matched), we hypothesized that asthma in infanthood or early…

  12. The effect of medical treatment of attention deficit hyperactivity disorder (ADHD) on foster care caseloads

    DEFF Research Database (Denmark)

    Fallesen, Peter; Wildeman, Christopher

    2015-01-01

    = 157,938) in the period from 1998 to 2010 to show that increasing medical treatment of attention deficit hyperactivity disorder (ADHD) accounts for a substantial share of the decrease in foster care caseloads. According to our estimates, the decline in foster care caseloads during this period would...... problems could also have a powerful effect on foster care caseloads....

  13. Measured Gene-by-Environment Interaction in Relation to Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Nigg, Joel; Nikolas, Molly; Burt, S. Alexandra

    2010-01-01

    Objective: To summarize and evaluate the state of knowledge regarding the role of measured gene-by-environment interactions in relation to attention-deficit/hyperactivity disorder. Method: A selective review of methodologic issues was followed by a systematic search for relevant articles on measured gene-by-environment interactions; the search…

  14. Writing Characteristics of Students with Attention Deficit Hyperactive Disorder: A Meta-Analysis

    Science.gov (United States)

    Graham, Steve; Fishman, Evan J.; Reid, Robert; Hebert, Michael

    2016-01-01

    Students with Attention Deficit Hyperactivity Disorders (ADHD) frequently experience significant difficulty mastering basic academic skills. This meta-analysis focuses on one specific potential area of learning difficulties for these students: namely, writing. To identify the extent and depth of the potential writing challenges faced by students…

  15. Development of a Family-School Intervention for Young Children with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Mautone, Jennifer A.; Marshall, Stephen A.; Sharman, Jaclyn; Eiraldi, Ricardo B.; Jawad, Abbas F.; Power, Thomas J.

    2012-01-01

    Although numerous studies have evaluated the effectiveness of multimodal psychosocial interventions for children with attention deficit hyperactivity disorder, these programs are limited in that there has not been an explicit focus on the connection between family and school. This study was designed to develop and pilot test a family-school…

  16. Recognizing and Treating Attention-Deficit/Hyperactivity Disorder in College Students

    Science.gov (United States)

    Prevatt, Frances; Young, Joel L.

    2014-01-01

    Traditionally diagnosed in children, attention-deficit/hyperactivity disorder (ADHD) is now regarded as a life span condition. The academic difficulties experienced by children and adolescents with ADHD have been observed to continue into young adulthood. Treatment outcome studies demonstrate that behavioral and pharmacotherapeutic interventions…

  17. Attention-Deficit/Hyperactivity Disorders among Students in Christian Colleges and Universities

    Science.gov (United States)

    Johnson, Jacob J.

    2011-01-01

    This article explores current research, diagnosis, and common problems of attention deficit hyperactivity disorder (ADHD) among Christian college and university students. For years, ADHD was believed to dissipate as children mature, but current research contradicts that belief. Proctor (2009) and others detail the continuance of ADHD into…

  18. Including Students with Attention-Deficit/Hyperactivity Disorder in Mainstream Schools

    Science.gov (United States)

    Humphrey, Neil

    2009-01-01

    Around 80% of pupils with attention deficit disorders are educated in mainstream schools. The difficulties relating to inattention, impulsivity and hyperactivity experienced by such pupils present mainstream educators with a unique set of challenges and opportunities. In this article, Neil Humphrey, Senior Lecturer in the Psychology of Education…

  19. What Knowledge and Conceptions Do Irish Primary Schoolteachers Hold on Attention Deficit Hyperactivity Disorder?

    Science.gov (United States)

    Ward, Victoria Ann

    2014-01-01

    Attention deficit hyperactivity disorder (ADHD) diagnosis rates have increased significantly in recent times. A teacher's role is crucial in determining if a child will be referred for an ADHD assessment. Teachers' opinions and observations are also required for and play a huge role in the actual assessment process. For this reason,…

  20. Determining Eligibility for Educational Services for Students with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Spencer, Twila Elaine

    2012-01-01

    The purpose of this study is to educate administrators, teachers and parents on educational services available to students diagnosed with attention deficit hyperactivity disorder (ADHD). Schools are required by federal and state laws to provide a student with a disability a free appropriate public education (FAPE) in the least restrictive…

  1. Stimulants and Cardiovascular Events in Youth with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Olfson, Mark; Huang, Cecilia; Gerhard, Tobias; Winterstein, Almut G.; Crystal, Stephen; Allison, Paul D.; Marcus, Steven C.

    2012-01-01

    Objective: This study examined associations between stimulant use and risk of cardiovascular events and symptoms in youth with attention-deficit/hyperactivity disorder and compared the risks associated with methylphenidate and amphetamines. Method: Claims were reviewed of privately insured young people 6 to 21 years old without known…

  2. Using Self-Regulated Strategy Development for Written Expression with Students with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Reid, Robert; Hagaman, Jessica L.; Graham, Steve

    2014-01-01

    This review assessed the use of self-regulated strategy development (SRSD) for teaching written composition strategies to students with attention deficit hyperactivity disorders. We examined the participants and the settings in which SRSD has been used, the writing strategies tested, genres addressed, and the effects of SRSD on outcome measures.…

  3. Body Movements of Boys with Attention Deficit Hyperactivity Disorder (ADHD) during Computer Video Game Play.

    Science.gov (United States)

    Farrace-DiZinno, Anna Marie; Douglas, Graham; Houghton, Stephen; Lawrence, Vivienne; West, John; Whiting, Ken

    2001-01-01

    Describes a study that recorded the type and severity of body movements of 79 boys with ADHD (attention deficit hyperactivity disorder) and 67 non-ADHD boys while playing a computer video game. Results of multivariate analysis of variance showed no statistically significant differences in body movements between ADHD and non-ADHD boys. (Author/LRW)

  4. Caregiver Survey of Pharmacotherapy to Treat Attention Deficit/Hyperactivity Disorder in Individuals with Williams Syndrome

    Science.gov (United States)

    Martens, Marilee A.; Seyfer, Daisha L.; Andridge, Rebecca R.; Foster, Jessica E. A.; McClure, Kelsey E.; Coury, Daniel L.

    2013-01-01

    Williams syndrome (WS) is a genetic condition characterized by a unique neurocognitive and behavioral profile, including increased incidence of attention deficit/hyperactivity disorder (ADHD). The purpose of the present study was to examine the perceived helpfulness and side effects of medications used to treat ADHD (methylphenidate class,…

  5. Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. Fourth Edition

    Science.gov (United States)

    Barkley, Russell A., Ed.

    2014-01-01

    Widely regarded as the standard clinical reference, this volume provides the best current knowledge about attention-deficit/hyperactivity disorder (ADHD) in children, adolescents, and adults. The field's leading authorities address all aspects of assessment, diagnosis, and treatment, including psychological therapies and pharmacotherapy. Core…

  6. Study of Anxiety in Parents and Children with Attention Deficit with Hyperactivity Disorder

    Science.gov (United States)

    Sánchez, Jose Juan Castro; Bermúdez, M. Olga Escandell; Sevilla, M. del Sol Fortea; Hernán-Pérez, Alejandra Sanjuán

    2015-01-01

    The identification of factors that influence attention deficit/hyperactivity disorder (ADHD) will help to develop intervention strategies for the personal and social adjustment of these individuals. The goal of the study is to assess the perception of anxiety in a group of children and adolescents with ADHD and the anxiety that their parents…

  7. Anxiety and disruptive behavior mediate pathways from attention-deficit/hyperactivity disorder to depression

    NARCIS (Netherlands)

    Roy, Arunima; Oldehinkel, Albertine J; Verhulst, Frank C; Ormel, Johan; Hartman, Catharina A

    2014-01-01

    Objective: The progression to depression in children with attention-deficit/hyperactivity disorder (ADHD) is not clearly understood. To clarify this relationship, we tested the following hypotheses in a population-based study: (1) children with ADHD have a higher risk of developing depression than c

  8. Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Neale, Benjamin M.; Medland, Sarah; Ripke, Stephan; Anney, Richard J. L.; Asherson, Philip; Buitelaar, Jan; Franke, Barbara; Gill, Michael; Kent, Lindsey; Holmans, Peter; Middleton, Frank; Thapar, Anita; Lesch, Klaus-Peter; Faraone, Stephen V.; Daly, Mark; Nguyen, Thuy Trang; Schafer, Helmut; Steinhausen, Hans-Christoph; Reif, Andreas; Renner, Tobias J.; Romanos, Marcel; Romanos, Jasmin; Warnke, Andreas; Walitza, Susanne; Freitag, Christine; Meyer, Jobst; Palmason, Haukur; Rothenberger, Aribert; Hawi, Ziarih; Sergeant, Joseph; Roeyers, Herbert; Mick, Eric; Biederman, Joseph

    2010-01-01

    Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. Thus additional genome-wide association studies (GWAS) are needed. Method: We used case-control analyses of 896 cases…

  9. Characteristics of Placebo Responders in Pediatric Clinical Trials of Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Newcorn, Jeffrey H.; Sutton, Virginia K.; Zhang, Shuyu; Wilens, Timothy; Kratochvil, Christopher; Emslie, Graham J.; D'Souza, Deborah N.; Schuh, Leslie M.; Allen, Albert J.

    2009-01-01

    Objective: Understanding placebo response is a prerequisite to improving clinical trial methodology. Data from placebo-controlled trials of atomoxetine in the treatment of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) were analyzed to identify demographic and clinical characteristics that might predict placebo…

  10. Neurofeedback as an Intervention to Improve Reading Achievement in Students with Attention- Deficit/Hyperactivity Disorder, Inattentive Subtype

    Science.gov (United States)

    La Marca, Jeffry P.; O'Connor, Rollanda E.

    2016-01-01

    Research consistently demonstrates that attention deficits have a deleterious effect on academic achievement. Impairments in attention, and not hyperactivity/impulsivity, are associated with learning difficulties and academic problems in students with attention-deficit/hyperactivity disorder (ADHD). To date, most studies have focused on symptoms…

  11. Distinguishing between attention-deficit hyperactivity and fetal alcohol spectrum disorders in children: clinical guidelines

    OpenAIRE

    Elizabeth Peadon; Elliott, Elizabeth J

    2010-01-01

    Elizabeth Peadon, Elizabeth J ElliottDiscipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, AustraliaAbstract: Fetal alcohol spectrum disorders (FASD) are the physical and neurodevelopmental outcomes of fetal alcohol exposure. The behavioral phenotype of children with FASD includes difficulties with executive function, memory, planning, processing speed, and attention. Although attention deficit hyperactivity disorder (ADHD) is diagnosed in up to 94% ...

  12. Attention-Deficit Hyperactivity Disorder in Children – Role of Behaviour Therapy and Parent Training Program

    OpenAIRE

    Beena Johnson

    2014-01-01

    Attention deficit hyperactivity disorder (ADHD) is a common behavioural disorder of childhood. It is a major public health problem. Children with ADHD have significant impairment in sustaining attention and this in turn will have negative impact on the academic performance and social-emotional development of the child. Most of the children present to child guidance clinic between the ages of 5-10 years. But ADHD can be problematic in pre-school age group and can continue into the adolescence....

  13. High dose methylphenidate treatment in adult attention deficit hyperactivity disorder: a case report

    Directory of Open Access Journals (Sweden)

    Liebrenz Michael

    2012-05-01

    Full Text Available Abstract Introduction Stimulant medication improves hyperactivity, inattention, and impulsivity in both pediatric and adult populations with Attention Deficit Hyperactivity Disorder (ADHD. However, data regarding the optimal dosage in adults is still limited. Case presentation We report the case of a 38-year-old Caucasian patient who was diagnosed with Attention Deficit Hyperactivity Disorder when he was nine years old. He then received up to 10 mg methylphenidate (Ritalin® and 20 mg sustained-release methylphenidate (Ritalin SR® daily. When he was 13, his medication was changed to desipramine (Norpramin®, and both Ritalin® and Ritalin SR® were discontinued; and at age 18, when he developed obsessive-compulsive symptoms, his medication was changed to clomipramine (Anafranil® 75 mg daily. Still suffering from inattention and hyperactivity, the patient began college when he was 19, but did not receive stimulant medication until three years later, when Ritalin® 60 mg daily was re-established. During the 14 months that followed, he began to use Ritalin® excessively, both orally and rectally, in dosages from 4800-6000 mg daily. Four years ago, he was referred to our outpatient service, where his Attention Deficit Hyperactivity Disorder was re-evaluated. At that point, the patient’s daily Ritalin® dosage was reduced to 200 mg daily orally, but he still experienced pronounced symptoms of, Attention Deficit Hyperactivity Disorder so this dosage was raised again. The patient’s plasma levels consistently remained between 60–187 nmol/l—within the recommended range—and signs of his obsessive-compulsive symptoms diminished with fluoxetine 40 mg daily. Finally, on a dosage of 378 mg extended-release methylphenidate (Concerta®, his symptoms of Attention Deficit Hyperactivity Disorder have improved dramatically and no further use of methylphenidate has been recorded during the 24 months preceding this report. Conclusions Symptoms of

  14. Neuropsychological Functioning of Girls with Attention-deficit/Hyperactivity Disorder Followed Prospectively into Adolescence: Evidence for Continuing Deficits?

    OpenAIRE

    Hinshaw, Stephen P.; Carte, Estol T.; Fan, Catherine; Jassy, Jonathan S.; Owens, Elizabeth B.

    2007-01-01

    Prospectively followed girls with attention-deficit/hyperactivity disorder (ADHD), along with a matched comparison sample, five years after childhood neuropsychological assessments. Follow-up neuropsychological measures emphasized attentional skills, executive functions, and language abilities. Paralleling childhood findings, the childhood-diagnosed ADHD group displayed moderate to large deficits in executive/attentional performance as well as rapid naming, relative to the comparison group, a...

  15. Meditation-Based Training: A Possible Intervention for Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Baijal, Shruti; Gupta, Rashmi

    2008-01-01

    Recent studies suggest that training-based measures are effective in improving cognitive skills. Meditation-based training has produced lasting changes in brain and cognitive functions. This technique of mental training exhibits neuroplasticity in the attentional networks, exhibiting superior performance, especially in the domain of attention and executive control processing, which is impaired in attention deficit hyperactivity disorder (ADHD). Although intervention techniques for ADHD are we...

  16. Evaluation of Oxidative Metabolism in Child and Adolescent Patients with Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Kul, Muslum; Unal, Fatih; Kandemir, Hasan; Sarkarati, Bahram; Kilinc, Kamer; Kandemir, Sultan Basmacı

    2015-01-01

    Objective Oxidative metabolism is impaired in several medical conditions including psychiatric disorders, and this imbalance may be involved in the etiology of these diseases. The present study evaluated oxidative balance in pediatric and adolescent patients with attention deficit hyperactivity disorder (ADHD). Methods The study included 48 children and adolescents (34 male, 14 female) with ADHD who had no neurological, systemic, or comorbid psychiatric disorders, with the exception of opposi...

  17. The Treatment of Comorbid Attention-Deficit/Hyperactivity Disorder (ADHD) and Anxiety in Children

    OpenAIRE

    Jarrett, Matthew Adam

    2009-01-01

    The current study evaluated a treatment designed specifically for children with attention-deficit/hyperactivity disorder (ADHD) and anxiety. The experimental treatment involved a combination of parent management training for ADHD and family-based treatment for anxiety. Sessions lasted approximately 90 minutes, and the treatment consisted of 10 weekly sessions. 8 children ages 8-12 with ADHD, Combined Type (ADHD-C) and at least one of three anxiety disorders (separation anxiety disorder, gener...

  18. Color naming deficits and attention-deficit/hyperactivity disorder: A retinal dopaminergic hypothesis

    Directory of Open Access Journals (Sweden)

    Tannock Rosemary

    2006-01-01

    Full Text Available Abstract Background Individuals with Attention-Deficit/Hyperactive Disorder (ADHD have unexplained difficulties on tasks requiring speeded processing of colored stimuli. Color vision mechanisms, particularly short-wavelength (blue-yellow pathways, are highly sensitive to various diseases, toxins and drugs that alter dopaminergic neurotransmission. Thus, slow color processing might reflect subtle impairments in the perceptual encoding stage of stimulus color, which arise from hypodopaminergic functioning. Presentation of hypotheses 1 Color perception of blue-yellow (but not red-green stimuli is impaired in ADHD as a result of deficient retinal dopamine; 2 Impairments in the blue-yellow color mechanism in ADHD contribute to poor performance on speeded color naming tasks that include a substantial proportion of blue-yellow stimuli; and 3 Methylphenidate increases central dopamine and is also believed to increase retinal dopamine, thereby normalizing blue-yellow color perception, which in turn improves performance on the speeded color naming tasks. Testing the hypothesis Requires three approaches, including:1 direct assessment of color perception in individuals with ADHD to determine whether blue-yellow color perception is selectively impaired; 2 determination of relationship between performance on neuropsychological tasks requiring speeded color processing and color perception; and 3 randomized, controlled pharmacological intervention with stimulant medication to examine the effects of enhancing central dopamine on color perception and task performance Implications of hypothesis If substantiated, the findings of color perception problems would necessitate a re-consideration of current neuropsychological models of attention-deficit/hyperactivity disorder, guide psycho-education, academic instruction, and require consideration of stimulus color in many of the widely used neuropsychological tests.

  19. Dissociation of working memory impairments and attention-deficit/hyperactivity disorder in the brain

    OpenAIRE

    Mattfeld, Aaron T.; Susan Whitfield-Gabrieli; Joseph Biederman; Thomas Spencer; Ariel Brown; Ronna Fried; Gabrieli, John D. E.

    2015-01-01

    Prevailing neuropsychological models of attention-deficit/hyperactivity disorder (ADHD) propose that ADHD arises from deficits in executive functions such as working memory, but accumulating clinical evidence suggests a dissociation between ADHD and executive dysfunctions. This study examined whether ADHD and working memory capacity are behaviorally and neurobiologically separable using functional magnetic resonance imaging (fMRI). Participants diagnosed with ADHD in childhood who subsequentl...

  20. Psychological compensation in attention deficit hyperactivity disorder - application of a theoretical framework

    OpenAIRE

    Merkt, Anne Christine Julia (Dr.)

    2014-01-01

    The term compensation is widely used in every-day language, in psychological research, and also discussed in the context of Attention Deficit Hyperactivity Disorder (ADHD). However, few studies have looked at psychological compensation in ADHD systematically and theory based. Compensation can be inferred if a deficit (i.e., a mismatch between skill and environmental demand) is counterbalanced by the investment of more effort, the utilization of latent or the acquisition of new skills. Based o...

  1. Dopamine Appetite and Cognitive Impairment in Attention Deficit/Hyperactivity Disorder

    OpenAIRE

    Jonathan Williams; Eric Taylor

    2004-01-01

    The underlying defects in ADHD (Attention Deficit/Hyperactivity Disorder) are not yet clear. The current paper tests three existing theories: State Regulation, Cognitive Deficit, and Temporal Difference (TD) learning. We present computational simulations of the Matching Familiar Figures Task and compare these with the experimental results reported by Sonuga- Barke (2002). The TD model contains four parameters: the learning rate, discounting for future rewards, br...

  2. Effects of methylphenidate on attentional set-shifting in a genetic model of attention-deficit/hyperactivity disorder

    OpenAIRE

    Cao Ai-hua; Yu Lin; Wang Yu-wei; Wang Jun-mei; Yang Le-jin; Lei Ge-fei

    2012-01-01

    Abstract Background Although deficits of attentional set-shifting have been reported in individuals with attention deficit/hyperactivity disorder (ADHD), it is rarely examined in animal models. Methods This study compared spontaneously hypertensive rats (SHRs; a genetic animal model of ADHD) and Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rats (normoactive control strains), on attentional set-shifting task (ASST) performance. Furthermore, the dose-effects of methylphenidate (MPH) on attentiona...

  3. Attention deficit hyperactivity disorder in the light of the epigenetic paradigm

    Directory of Open Access Journals (Sweden)

    Viviane eSchuch

    2015-09-01

    Full Text Available Attention deficit hyperactivity disorder (ADHD is a highly prevalent neurodevelopmental disorder characterized by a definite behavioral pattern that might lead to performance problems in the social, educational or work environments. In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V, the symptoms of ADHD were restricted to those associated with cognitive (attention deficit and behavioral (hyperactivity/impulsivity deficits, while deficient emotional self-regulation (DESR, a relevant source of morbidity, was left out. The etiology of it is complex, as its exact causes have not yet been fully elucidated. ADHD seems to arise from a combination of various genetic and environmental factors that alter the developing brain, resulting in structural and functional abnormalities. The aim of this paper was to review epigenetics and ADHD focused on how multidimensional mechanisms influence the behavioral phenotype.

  4. Differential Diagnosis of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder by Means of Inhibitory Control and "Theory of Mind"

    Science.gov (United States)

    Buhler, Eva; Bachmann, Christian; Goyert, Hannah; Heinzel-Gutenbrunner, Monika; Kamp-Becker, Inge

    2011-01-01

    Autism spectrum disorders (ASD) and attention deficit hyperactivity disorders (ADHD) are both associated with deficits in executive control and with problems in social contexts. This study analyses the variables inhibitory control and theory of mind (ToM), including a developmental aspect in the case of the latter, to differentiate between the…

  5. The Speed of Visual Attention and Motor-Response Decisions in Adult Attention-Deficit/Hyperactivity Disorder

    DEFF Research Database (Denmark)

    Cross-Villasana, Fernando; Finke, Kathrin; Hennig-Fast, Kristina;

    2015-01-01

    Abstract Background: Adults with Attention Deficit/Hyperactivity Disorder (ADHD) exhibit slowed reaction times (RTs) in various attention tasks. The exact origins of this slowing, however, have not been yet established. Potential candidates are early sensory processes mediating the deployment of ...

  6. Parenting in adults with attention-deficit/hyperactivity disorder (ADHD).

    Science.gov (United States)

    Johnston, Charlotte; Mash, Eric J; Miller, Natalie; Ninowski, Jerilyn E

    2012-06-01

    Although the validity of adult ADHD is well established and research has identified a variety of impairments associated with the condition in adults, study of how ADHD impacts an adult's ability to parent has been relatively neglected. Parenting is a particularly important domain of functioning given the familial nature of the disorder and emerging evidence that parenting behaviors play a role in the development or maintenance of child ADHD symptoms, comorbid psychopathologies, and other associated difficulties. In this paper, we focus on three broad categories of cognitive dysfunction proposed across models of ADHD - cognitive processes (e.g., working memory, planning, and inhibitory control), self-regulation deficits (e.g., self-monitoring of performance to detect errors or the need for regulation of behavior and/or emotions), and motivational or arousal difficulties (e.g., response to incentives, delay aversion). We consider how these deficits may lead to impairments in the parenting behaviors of effective behavioral control and emotional responsiveness, and review the available evidence regarding parenting in adults with ADHD symptoms. We conclude by noting the limitations in existing studies, and argue for further research that is theoretically grounded in how core deficits of ADHD may be related to dimensions of parenting. The implications of an improved understanding of how ADHD impacts parenting for the development of early intervention or prevention programs are outlined. PMID:22459785

  7. Zinc, ferritin, magnesium and copper in a group of Egyptian children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Mahmoud Magdy M

    2011-12-01

    Full Text Available Abstract Background Attention deficit hyperactivity disorder is a behavioral syndrome of childhood characterized by inattention, hyperactivity and impulsivity. There were many etiological theories showed dysfunction of some brain areas that are implicated in inhibition of responses and functions of the brain. Minerals like zinc, ferritin, magnesium and copper may play a role in the pathogenesis and therefore the treatment of this disorder. Objective This study aimed to measure levels of zinc, ferritin, magnesium and copper in children with attention deficit hyperactivity disorder and comparing them to normal. Methods This study included 58 children aged 5-15 years with attention deficit hyperactivity disorder attending Minia University Hospital from June 2008 to January 2010. They were classified into three sub-groups: sub-group I included 32 children with in-attentive type, sub-group II included 10 children with hyperactive type and sub-group III included 16 children with combined type according to the DSM-IV criteria of American Psychiatric Association, 2000. The control group included 25 apparently normal healthy children. Results Zinc, ferritin and magnesium levels were significantly lower in children with attention deficit hyperactivity disorder than controls (p value 0.04, 0.03 and 0.02 respectively, while copper levels were not significantly different (p value 0.9. Children with inattentive type had significant lower levels of zinc and ferritin than controls (p value 0.001 and 0.01 respectively with no significant difference between them as regards magnesium and copper levels (p value 0.4 and 0.6 respectively. Children with hyperactive type had significant lower levels of zinc, ferritin and magnesium than controls (p value 0.01, 0.02 and 0.02 respectively with no significant difference between them as regards copper levels (p value 0.9. Children with combined type had significant lower levels of zinc and magnesium than controls (p value 0

  8. Neuroanatomical deficits correlate with executive dysfunction in boys with attention deficit hyperactivity disorder.

    Science.gov (United States)

    He, Ning; Li, Fei; Li, Yuanyuan; Guo, Lanting; Chen, Lizhou; Huang, Xiaoqi; Lui, Su; Gong, Qiyong

    2015-07-23

    Previous structural imaging studies have revealed gray matter volume abnormalities to reflect the etiology of attention deficit hyperactivity disorder (ADHD), however, which are confounded by age, medication and comorbidity and also ignore the core feature of brain structure in the executive impairments of ADHD. In the present study, we explored gray matter volume abnormalities in male children and adolescents with ADHD who were drug-naive and without comorbidities, and tried to connect structural data and behavioral executive dysfunction to provide more information regarding the brain-behavior relationships in ADHD. Seventy-two male subjects (37 patients and 35 controls) underwent three-dimensional high-resolution structural magnetic resonance imaging and executive function assessments, including the Stroop Color-Word Test and Wisconsin Card Sorting Test (WCST). Voxel-based morphometry with diffeomorphic anatomical registration through exponentiated Lie algebra was used to identify gray matter volume differences between the ADHD and controls. Correlation analyses were performed to identify neuroanatomical deficits that were associated with executive dysfunctions. Significantly reduced gray matter volumes were identified in the right orbitofrontal cortex, right primary motor/premotor cortex, left anterior cingulate cortex and left posterior midcingulate cortex of ADHD patients compared with controls (PADHD at early illness stage. The correlations between structural abnormalities and executive dysfunction suggest that neuroanatomical substrate deficits are implicated in the pathophysiology of ADHD. PMID:26049007

  9. Fluoxetine Monotherapy in Attention-Deficit/Hyperactivity Disorder and Comorbid Non-Bipolar Mood Disorders in Children and Adolescents

    Science.gov (United States)

    Quintana, Humberto; Butterbaugh, Grant J.; Purnell, William; Layman, Ann K.

    2007-01-01

    Children with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for developing comorbid non-bipolar mood disorders. Fluoxetine monotherapy is an established treatment for pediatric mood disorders; however its efficacy in ADHD and comorbid mood disorder is unknown. Therefore, we evaluated 30 children who met DSM-IV criteria for…

  10. Neurocognitive Profile of Children with Attention Deficit Hyperactivity Disorders (ADHD: A comparison between subtypes.

    Directory of Open Access Journals (Sweden)

    Nastaran Ahmadi

    2014-12-01

    Full Text Available The aim of this study was to examine the differences between ADHD subtypes in executive function tasks compared to themselves and normal controls.In this study, 45 school aged children with Attention Deficit Hyperactivity Disorder (ADHD and 30 normal children who were matched based on age and IQ score in Wechsler Intelligence Scale for Children-Revised (WISC-R were compared in terms of executive function. We used Wisconsin Sorting Card Test to assess executive function in both groups. We also used children's scores in Children Symptom Inventory-4 (CSI-4 for diagnosing ADHD and specifying ADHD subtypes. Data were entered in SPSS-17 and analyzed by T-test and ANOVA static tests to clarify the differences between ADHD and controls and between ADHD subtypes. Scheffe's test was also used to identify which groups were different from one another. The mean and standard divisions (SD were used for descriptive analysis.ADHD subtypes are significantly different in terms of perseverative responses (p≤ 0/01 and perseverative errors (p≤ 0/001. Based on Scheffe's test, Attention Deficit Hyperactivity Disorders-Hyperactive type (ADHD-H is not that different from Attention Deficit Hyperactivity Disorders-Inattention type (ADHD-I and Attention Deficit Hyperactivity Disorders-Combined type (ADHD-C, but there are significant responses and perseverative differences between ADHD-I and ADHD-C in terms of perseverative errors. ADHD-C shows more perseverative responses and perseverative errors than ADHD-I.The findings of this study revealed that executive function patterns are different in children with ADHD compared to normal children. In this study it was also found that ADHD subtypes are also different in terms of perseveration and response inhibition domains; ADHD-C has more deficits in these domains.

  11. Comorbidity of Learning Disorders and Attention Deficit Hyperactivity Disorder in a Sample of Omani Schoolchildren

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    Watfa S. Al-Mamari

    2015-11-01

    Full Text Available Objectives: The estimated worldwide prevalence of learning disorders (LDs is approximately 2‒10% among school-aged children. LDs have variable clinical features and are often associated with other disorders. This study aimed to examine the comorbidity of LDs and attention deficit hyperactivity disorder (ADHD among a sample of schoolchildren in Oman. Methods: This study was conducted between January 2014 and January 2015 at the Sultan Qaboos University, Muscat, Oman. The Learning Disabilities Diagnostic Inventory (LDDI and the 28- item version of the Conners’ Teacher Rating Scale was completed by classroom teachers to determine the existence of LD and ADHD symptoms in 321 children in grades 1‒4 who had been referred to a learning support unit for LDs from elementary schools in Muscat. Results: The mean age of the students was 8.5 years. Among the cohort, 30% were reported to have symptoms of ADHD, including conduct problems (24%, hyperactivity (24% and inattentivepassive behaviours (41%. Male students reportedly exhibited greater conduct problems and hyperactivity than females. However, there were no gender differences noted between LDDI scores. Conclusion: This study suggests that Omani schoolchildren with LDs are likely to exhibit signs of ADHD. The early identification of this disorder is essential considering the chronic nature of ADHD. For interventional purposes, multidisciplinary teams are recommended, including general and special educators, clinical psychologists, school counsellors, developmental or experienced general paediatricians and child psychiatrists.

  12. Computer games for user engagement in attention deficit hyperactivity disorder (ADHD) monitoring and therapy

    OpenAIRE

    Craven, Michael P; Groom, Madeleine J.

    2015-01-01

    State-of-the-art computer games and psychological tests for symptom monitoring and therapy in Attention Deficit Hyperactivity Disorder (ADHD) are explored and reviewed. Three foci for research studies are identified: task (human performance) focus; educational focus; medical/clinical focus. It is found that game designs in the literature include a variety of tests of cognition mostly dependent on attention and executive functions (inhibitory motor control, working memory, interference su...

  13. Obesity, Attention Deficit-Hyperactivity Disorder and the Dopaminergic Reward System

    OpenAIRE

    Campbell, Benjamin Charles; Eisenberg, Dan

    2007-01-01

    The obesity epidemic has focused attention on obesity’s health consequences beyond cardio-vascular disease and diabetes. To evaluate the potential consequences of obesity for Attention Deficit-Hyperactivity Disorder (ADHD), we surveyed the literature. Current findings link both obesity and ADHD to the dopamine system and implicate dopamine genes in body weight, eating, and ADHD. Detailed consideration suggests that dopaminergic changes in the prefrontal cortex among individuals wi...

  14. Sensation-to-Cognition Cortical Streams in Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Carmona, Susana; Hoekzema, Elseline; Castellanos, Francisco X.; García-García, David; Lage-Castellanos, Agustín; Van Dijk, Koene R. A.; Navas-Sánchez, Francisco J.; Martínez, Kenia; Desco, Manuel; Sepulcre, Jorge

    2015-01-01

    We sought to determine whether functional connectivity streams that link sensory, attentional, and higher-order cognitive circuits are atypical in attention-deficit/hyperactivity disorder (ADHD). We applied a graph-theory method to the resting-state functional magnetic resonance imaging data of 120 children with ADHD and 120 age-matched typically developing children (TDC). Starting in unimodal primary cortex—visual, auditory, and somatosensory—we used stepwise functional connectivity to calcu...

  15. Familiality of neural preparation and response control in childhood attention deficit-hyperactivity disorder

    OpenAIRE

    Albrecht, B.; Brandeis, D; Uebel, H.; Valko, L; H. Heinrich; Drechsler, R; Heise, A.; Müller, U C; Steinhausen, H.-C.; Rothenberger, A.; Banaschewski, T.

    2014-01-01

    BACKGROUND: Patients with attention deficit-hyperactivity disorder (ADHD) exhibit difficulties in multiple attentional functions. Although high heritability rates suggest a strong genetic impact, aetiological pathways from genes and environmental factors to the ADHD phenotype are not well understood. Tracking the time course of deviant task processing using event-related electrophysiological brain activity should characterize the impact of familiality on the sequence of cognitive functions fr...

  16. Attention-deficit hyperactive disorder presenting with school truancy in an adolescent: a case report

    OpenAIRE

    Muhammad, Noor Azimah; Wan Ismail, Wan Salwina; Tan, Chai Eng; Jaffar, Aida; Sharip, Shalisah; Omar, Khairani

    2011-01-01

    Attention-deficit hyperactive disorder (ADHD) is a psychiatric illness commonly diagnosed during the early years of childhood. In many adolescents with undiagnosed ADHD, presentation may not be entirely similar to that in younger children. These adolescents pose significant challenges to parents and teachers coping with their disability. Often adolescents with behavioural problems are brought to medical attention as a last resort. This case describes an adolescent who presented to a primary c...

  17. Cognitive Function in Childhood Epilepsy: Importance of Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Kang, Sung-Han; Yum, Mi-sun; Kim, Eun-Hee; Kim, Hyo-won; Ko, Tae-Sung

    2015-01-01

    Background and Purpose To determine how cognitive function is related to epilepsy classification and comorbid attention deficit hyperactivity disorder (ADHD) in children with newly diagnosed epilepsy of genetic or unknown etiology. Methods The medical records of children aged 6-16 years with newly diagnosed epilepsy of genetic or unknown etiology were reviewed retrospectively. The Korean Education Development Institute-Wechsler Intelligence Scale for Children and the Comprehensive Attention T...

  18. Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD).

    Science.gov (United States)

    Caballero, Miguel; Núñez, Fabiana; Ahern, Siobhán; Cuffí, Maria L; Carbonell, Lourdes; Sánchez, Silvia; Fernández-Dueñas, Víctor; Ciruela, Francisco

    2011-04-20

    Nowadays the pharmacological treatment of the attention deficit hyperactivity disorder (ADHD) is based on amphetamine derivatives (i.e. methylphenidate). However, these drugs induce a large array of adverse side effects, thus less aggressive psychostimulant drugs (i.e. caffeine) are being proposed in the management of ADHD. Following this tendency, we decided to study the possible therapeutic use of caffeine in an animal model of ADHD, namely the neonatal 6-hydroxy-dopamine (6-OHDA)-lesioned rat. Therefore, at postnatal day 7 rats were lesioned at the left striatum with 6-OHDA or with saline. Thereafter, at postnatal day 25 their activity and attention were measured with the Olton maze before caffeine was administered ad libitum in the drinking water. Next, after 14 days of caffeine treatment, we repeated these measurements to assess the effect of caffeine on motor activity and attention deficit. Interestingly, while no changes in the motor activity measurements were observed before and after caffeine administration, a significant improvement in the attention deficit of the 6-OHDA lesioned rats was achieved after caffeine treatment. Thus, our results led us to hypothesize that caffeine might be useful to manage the attention deficit during the prepubertal period of ADHD. PMID:21362462

  19. Pharmacological Treatment of Attention Deficit Hyperactivity Disorder in Children and Adolescents: Clinical Strategies

    OpenAIRE

    Shier, Anna C.; Thomas Reichenbacher; Ghuman, Harinder S.; Ghuman, Jaswinder K.

    2012-01-01

    Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder of childhood that can result in significant functional impairment, and if not adequately treated can lead to impaired quality of life. Pharmacotherapy is considered the first-line treatment for ADHD in children and adolescents. We review both recent literature and seminal studies regarding the pharmacological treatment of ADHD in children and adolescents. There is ample evidence for the efficacy and safety of...

  20. Assessment and management of attention-deficit hyperactivity disorder in adults

    OpenAIRE

    Weiss, Margaret; Murray, Candice

    2003-01-01

    ATTENTION-DEFICIT HYPERACTIVITY DISORDER (ADHD) IS ESTIMATED to affect 2%–6% of adults. The symptoms in adults with ADHD mirror those in children with the disorder and are associated with significant educational, occupational and interpersonal difficulties. Double-blind, placebo-controlled trials have established that adult ADHD is responsive to stimulant medication treatment. New medications and psychotherapeutic approaches are being developed in an effort to achieve optimal treatment effect...

  1. Prescribing of drugs for attention-deficit hyperactivity disorder in opioid maintenance treatment patients in Norway

    OpenAIRE

    Karlstad, Øystein; Furu, Kari; Skurtveit, Svetlana; Selmer, Randi

    2013-01-01

    Background: Attention-deficit hyperactivity disorder (ADHD) is a risk factor for development of substance use disorders. Treatment of ADHD with psychostimulants in patients on opioid maintenance treatment (OMT) has been restricted in Norway. We examined use of prescribed drugs for ADHD in OMT patients, and assessed co-medication with other psychotropics. Methods: Data were drawn from the nationwide Norwegian Prescription Database (NorPD), which includes all prescriptions filled at...

  2. Management of attention-deficit hyperactivity disorder in adults: focus on methylphenidate hydrochloride

    OpenAIRE

    Rajasree Nair; Moss, Shannon B

    2009-01-01

    Rajasree Nair, Shannon B MossBaylor Family Medicine Residency at Garland, Garland, Texas, USAAbstract: Attention-deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in young adults and causes significant psychosocial impairment and economic burden to society. Because of the paucity of long-term evidence and lack of national guidelines for diagnosis and management of adult ADHD, most of the data are based on experience derived from management of childhood ADHD...

  3. Attention deficit and hyperactivity disorder: case series of a secondary center

    OpenAIRE

    Coelho, Janine; Melo, Cláudia; Rocha, Felisbela; Santos, Sandra; Barros, Sara; Martins, Cecília

    2016-01-01

    Introduction: Attention deficit and hyperactivity disorder (ADHD) is the most frequent neuro comportamental condition in age school children. The symptoms include difficulty in controlling physical activity, impulsivity and/or inattention.Objective: To describe the characteristics of children with ADHD, in a second line hospital.Material and methods: Retrospective study of children with ADHD. Variables included were: age, sex, personal and family medical history, symptoms, comorbid disorders,...

  4. Is primary care ready to take on Attention Deficit Hyperactivity Disorder?

    OpenAIRE

    Thapar Anita; Thapar Ajay

    2002-01-01

    Abstract Background Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood psychiatric disorder. The management of ADHD has recently been highlighted. The National Institute of Clinical Excellence (NICE) and Scottish Intercollegiate Guidelines network (SIGN) have both produced management guidelines. Doctors working within Primary Care in countries such as the United States play an important role in the management of ADHD. In the United Kingdom however the role of doctors in pri...

  5. Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder

    OpenAIRE

    Stergiakouli, E.; Langley, K; Williams, H.; Walters, J.; Williams, N. M.; Suren, S; Giegling, I; Wilkinson, L. S.; Owen, M J; O'Donovan, M.C.; Rujescu, D.; Thapar, A; Davies, W.

    2011-01-01

    Deletions encompassing the X-linked STS gene (encoding steroid sulfatase) have been observed in subjects with neurodevelopmental disorders, including attention deficit hyperactivity disorder (ADHD). Recently, two single nucleotide polymorphisms (SNPs) within STS (rs12861247 and rs17268988) have been reported to be associated with ADHD risk and inattentive symptoms in ADHD, respectively. Using a UK sample of ADHD subjects (aged 5–18 years), we tested the hypothesis that rs12861247 is associate...

  6. Attention-Deficit/Hyperactivity Disorder: Is it Time to Reappraise the Role of Sugar Consumption?

    OpenAIRE

    Johnson, Richard J.; Mark S. Gold; Johnson, David R.; Ishimoto, Takuji; Lanaspa, Miguel A.; Zahniser, Nancy R.; AVENA, NICOLE M.

    2011-01-01

    Attention-deficit/hyperactivity disorder (ADHD) affects nearly 10% of children in the United States, and the prevalence of this disorder has increased steadily over the past decades. The cause of ADHD is unknown, although recent studies suggest that it may be associated with a disruption in dopamine signaling whereby dopamine D2 receptors are reduced in reward-related brain regions. This same pattern of reduced dopamine-mediated signaling is observed in various reward-deficiency syndromes ass...

  7. Overload: Regulating the Sources of Information about Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Shaitelman, Kenneth

    2005-01-01

    Information relating to attention-deficit/hyperactivity disorder (AD/HD) has flooded the consumer and medical markets in recent years. Information “overload†is often problematic, but it is especially the case with AD/HD. Those afflicted with the disorder are uniquely unsuited to make sense of the mass of information that is presented to them. The purpose of this article, therefore, is to examine whether any legal controls exist to regulate the flow of informati...

  8. Adult attention-deficit/hyperactivity disorder and nicotine use: a qualitative study of patient perceptions

    OpenAIRE

    Liebrenz, Michael; Frei, Anja; Fisher, Carl Erik; Gamma, Alex; Buadze, Anna; Eich, Dominique

    2014-01-01

    BACKGROUND Adult Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with high rates of comorbid substance use disorders, and cigarette smoking has a particularly high prevalence in this population. However, there is an ongoing debate as to whether this tobacco use is an attempt at "self-medication" or due to behavioral disinhibition. There is a surprising lack of qualitative studies that investigate the subjective perceptions of adults with ADHD regarding cigarette smoking. The pr...

  9. Attention Deficit/Hyperactivity Disorder: A Focused Overview for Children’s Environmental Health Researchers

    OpenAIRE

    Aguiar, Andréa; Eubig, Paul A.; Schantz, Susan L

    2010-01-01

    Objectives Attention deficit/hyperactivity disorder (ADHD) is the most frequently diagnosed childhood neurobehavioral disorder. Much research has been done to identify genetic, environmental, and social risk factors for ADHD; however, we are still far from fully understanding its etiology. In this review we provide an overview of diagnostic criteria for ADHD and what is known about its biological basis. We also review the neuropsychological functions that are affected in ADHD. The goal is to ...

  10. Prevention of Serious Conduct Problems in Youth with Attention Deficit/Hyperactivity Disorder

    OpenAIRE

    Villodas, Miguel T.; Pfiffner, Linda J.; McBurnett, Keith

    2012-01-01

    The purpose of this review is to discuss issues in the prevention of serious conduct problems among children and adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). We begin by reviewing research on the common genetic and environmental etiological factors, developmental trajectories, characteristics, and impairments associated with ADHD and comorbid Oppositional Defiant and Conduct Disorders. Next, we present empirically-based models for intervention with children and adolescent...

  11. Brain-Derived Neurotrophic Factor as a Biomarker in Children with Attention Deficit-Hyperactivity Disorder

    OpenAIRE

    Farshid Saadat; Maryam Kosha; Ali Amiry; Gholamreza Torabi

    2015-01-01

    Background: Evidence suggests that Brain-Derived Neurotrophic Factor (BDNF) is involved in the pathogenesis of Attention-Deficit Hyperactivity Disorder (ADHD), although experimental data regarding the contribution of BDNF concentration to this psychiatric disorder are controversial. Aim: To evaluate the plasma levels of BDNF in patients with ADHD. Material and Methods: In this cross sectional study, ADHD and controls were recruited from the outpatient clinic of the ...

  12. Concomitant Pharmacotherapy of Psychotropic Medications in EU Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Sikirica, Vanja; Fridman, Moshe; Bruno, Amanda; Hodgkins, Paul; Erder, M. Haim

    2013-01-01

    Background With preliminary data suggesting an increasing trend in attention-deficit/hyperactivity disorder (ADHD) prevalence in Europe, the use of psychotropic medications in this population needs to be better understood, particularly among patients with ADHD and no co-morbid psychiatric disorder. Methods Medical charts of patients aged 6–17 years with one or more ADHD diagnosis between January 1, 2004 and June 30, 2007, and use of ADHD medication were abstracted by physicians from six Europ...

  13. Association Between Adult Attention Deficit/Hyperactivity Disorder and Obesity in the US Population

    OpenAIRE

    Pagoto, S. L.; Curtin, C.; Lemon, S. C.; Bandini, L. G.; Schneider, K. L.; Bodenlos, J. S.; Ma, Y.

    2009-01-01

    Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder that affects approximately 2.9%–4.7% of US adults. Studies have revealed high rates of ADHD (26 – 61%) in patients seeking weight loss treatment suggesting an association between ADHD and obesity. The objective of the present study was to test the association between ADHD and overweight and obesity in the US population. Cross-sectional data from the Collaborative Psychiatric Epidemiology Surveys were used. Participa...

  14. Dissociable attentional and affective circuits in medication-naïve children with attention-deficit/hyperactivity disorder

    OpenAIRE

    Posner, Jonathan; Rauh, Virginia; Gruber, Allison; Gat, Inbal; Wang, Zhishun; Bradley S. Peterson

    2013-01-01

    Current neurocognitive models of attention-deficit/hyperactivity disorder (ADHD) suggest that neural circuits involving both attentional and affective processing make independent contributions to the phenomenology of the disorder. However, a clear dissociation of attentional and affective circuits and their behavioral correlates has yet to be shown in medication-naïve children with ADHD. Using resting-state functional connectivity MRI (rs-fcMRI) in a cohort of medication naïve children with (...

  15. Narrative review of scales assessing attention-deficit/hyperactivity disorder in children and adolescents

    Directory of Open Access Journals (Sweden)

    María Evangelina Herrán Paz

    2014-01-01

    Full Text Available Context. Attention-deficit/hyperactivity disorder is a common neurobehavioral disorder in school-age population and is a major driver of mental health consultation. Diagnosis is hindered by the difficulty of objectively assessing subjective aspects such as inattention or impulsivity. Purpose. To briefly describe the most widely used rating scales as tools for the diagnosis of attention-deficit/hyperactivity disorder, subtypes and comorbidities, based on a review of information available in MEDLINE, Medic America, Academic Search Complete and Mendeley databases. Analysis. This disorder is poorly understood in the family and school environment, which hampers detection and timely treatment. Rating scales have advantages and disadvantages, but they are undoubtedly important for an initial approach to the clinical manifestations of attention-deficit/hyperactivity disorder. Conclusion. There is a need for better diagnostic tools or scales that take into account the stage of neurodevelopment, other developmental stages, gender differences, sociocultural aspects and diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition.

  16. Comorbidity and confounding factors in attention-deficit/hyperactivity disorder and sleep disorders in children

    Directory of Open Access Journals (Sweden)

    Huang YS

    2011-09-01

    Full Text Available Ya-Wen Jan1,2, Chien-Ming Yang1,3, Yu-Shu Huang4,51Department of Psychology, National Cheng-Chi University, Taipei; 2Sleep Center of Taipei Medical University Hospital, Taipei; 3The Research Center for Mind Brain and Learning, National Cheng-Chi University, Taipei; 4Department of Child Psychiatry and Sleep Center, Chang Gung Memorial Hospital, Taoyuan; 5College of Medicine, Chang Gung University, Taoyuan, TaiwanAbstract: Sleep problems are commonly reported in children with attention-deficit/hyperactivity disorder (ADHD symptoms. Research data regarding the complex and reciprocal relationship between ADHD and sleep disturbances has now accumulated. This paper is focused on the types of sleep problems that are associated with ADHD symptomatology, and attempts to untangle confounding factors and overlapping symptoms. The goal is also to present an updated overview of the pathophysiology of and treatment strategies for sleep problems in children with ADHD. The review also points out that future research will be needed to clarify further the other psychiatric comorbidities and side effects of medication in order to improve treatment outcomes and prevent misdiagnosis in clinical practice.Keywords: attention-deficit/hyperactivity disorder, sleep, children 

  17. Screening for attention-deficit/hyperactivity disorder in adult inpatients with psychiatric disorders.

    Science.gov (United States)

    Kumar, Geetha; Faden, Justin; Steer, Robert A

    2011-06-01

    The purpose was to assess the effectiveness of the adult ADHD Module from the MINI International Neuropsychiatric Interview (MINI) and the Conners' Adult ADHD Rating Scales: Screening Version DSM-IV ADHD Symptoms Total Scale (CAARS-S:SV) in screening for attention-deficit/hyperactivity (ADHD) disorder in patients hospitalized for other psychiatric disorders. Assessment measures were administered to 55 (50%) female and 55 (50%) male adult (>18 yr. old) inpatients. Only six (5%) of the 110 inpatients had been diagnosed with comorbid ADHD according to medical charts. In contrast, 55 (50%) patients met criteria for ADHD according to the MINI, and 39 (36%) patients met criteria on the CAARS-S:SV. The higher rates of prevalence for the MINI and the CAARS-S:SV were attributable to symptom criteria for ADHD being similar to those shared with comorbid disorders. PMID:21879629

  18. Children with Comorbid Speech Sound Disorder and Specific Language Impairment Are at Increased Risk for Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    McGrath, Lauren M.; Hutaff-Lee, Christa; Scott, Ashley; Boada, Richard; Shriberg, Lawrence D.; Pennington, Bruce F.

    2008-01-01

    This study focuses on the comorbidity between attention-deficit/hyperactivity disorder (ADHD) symptoms and speech sound disorder (SSD). SSD is a developmental disorder characterized by speech production errors that impact intelligibility. Previous research addressing this comorbidity has typically used heterogeneous groups of speech-language…

  19. Beyond diagnoses : attention deficit hyperactivity disorder vs. early onset bipolar disorder : A study of neurological diversity behind symptoms

    OpenAIRE

    2012-01-01

    Objective: The distinction between Bipolar Disorder (BD) and Attention Deficit/Hyperactivity Disorder (ADHD) in youths is difficult because of similar behaviour presentation. Delayed diagnosis and treatment of early onset psychiatric disorders is associated with considerable morbidity and mortality, and an adverse effect on psychosocial development and academic achievement. Identifying neuromotor and neurocognitive problems underlying similar symptoms may perhaps aid diagnostic accuracy, a...

  20. Pharmacological Management of Pediatric Patients with Comorbid Attention-Deficit Hyperactivity Disorder Oppositional Defiant Disorder.

    Science.gov (United States)

    Connor, Daniel F

    2015-10-01

    Attention-deficit hyperactivity disorder (ADHD) is a common developmental neurobiological condition of childhood characterized by age-inappropriate degrees of hyperactivity/impulsivity and inattention to tasks requiring sustained vigilance. Oppositional defiant disorder (ODD) is an externalizing behavior disorder characterized by difficulties with emotional and behavioral regulation that frequently brings the child into conflict with authority figures. In the clinical setting, ODD is the most common ADHD comorbidity. The combination portends more severe symptom severity, daily impairment, and a more at-risk prognosis than either disorder alone. We briefly review the literature on the characteristics and treatment of the ADHD and ODD child. A clinical approach to evaluation and treatment of ADHD and ODD is then presented. This approach emphasizes the importance of child and parent psychoeducation about the two disorders alone and in combination, the importance of behavioral management therapy approaches, the possible need for school and academic supports, and the decision to use evidence-based stimulant or non-stimulant ADHD medications depending on symptom severity combined with child and parental wishes and choice. PMID:26233632

  1. Relationship between acne vulgaris and attention-deficit/hyperactivity disorder symptoms in a clinical sample of women.

    Science.gov (United States)

    Bilgic, Ayhan; Bilgic, Özlem; Çolak, Rukiye Sivri; Altınyazar, Hilmi Cevdet

    2016-04-01

    Acne vulgaris has recently been reported to be associated with elevated rates of attention deficit/hyperactivity disorder in epidemiological studies. This report examines childhood and current attention-deficit/hyperactivity disorder symptoms in a clinical sample of female adults. Ninety-one women with acne vulgaris and 53 controls were included in this study. The aforementioned symptoms were measured in participants. No significant differences were found between patients and controls in any of the measurements. Contrary to the findings of epidemiological studies, this study did not uncover a link between acne vulgaris and attention-deficit/hyperactivity disorder. PMID:27192533

  2. Adults with attention-deficit/hyperactivity disorder - a brain magnetic resonance spectroscopy study

    DEFF Research Database (Denmark)

    Dramsdahl, Margaretha; Ersland, Lars; Plessen, Kerstin J; Haavik, Jan; Hugdahl, Kenneth; Specht, Karsten

    2011-01-01

    Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the right midfrontal region including the anterior cingulate cortex in adults...... two groups. Results: The ADHD group showed a significant reduction of Glu/Cre in the left midfrontal region compared to the controls. Conclusion: The reduction of Glu/Cre in the left midfrontal region in the ADHD group may reflect a glutamatergic deficit in prefrontal neuronal circuitry in adults with...

  3. Pregnancy and delivery complications and treatment approach in attention deficit hyperactivity disorder.

    Science.gov (United States)

    Aktepe, Evrim; Ozkorumak, Evrim; Tanriöver-Kandil, Sema

    2009-01-01

    Pregnancy, delivery complications and treatment approach were evaluated in 153 cases diagnosed with attention deficit hyperactivity disorder in the State Hospital of Antalya in the Child and Adolescent Psychiatry Polyclinic. Most of the cases had been delivered vaginally (74.5%). The most frequent delivery complication was asphyxia/hypoxia (15.6%). The agent most frequently preferred in the treatment regimen was methylphenidate (82.4%), which is a psychostimulant. The other drugs used were risperidone (29.4%), selective serotonin reuptake inhibitors (16.4%) and imipramine (4.6%). The most frequent side effect resulting from methylphenidate use was a decrease in appetite (34.9%). Attention deficit hyperactivity disorder often presents with comorbid disorders; in these cases, nonstimulant agents had to be added to methylphenidate for better treatment outcomes. Use of selective serotonin reuptake inhibitors in combined treatment and in cases with comorbidities is in agreement with the literature. Further studies of combined treatment regimens in attention deficit hyperactivity disorder are needed. PMID:20112604

  4. Comorbidity of Personality Disorders and Adult Attention Deficit Hyperactivity Disorder (ADHD)-Review of Recent Findings.

    Science.gov (United States)

    Matthies, Swantje; Philipsen, Alexandra

    2016-04-01

    Children suffering from attention deficit hyperactivity disorder (ADHD) may remit until adulthood. But, more than 60-80 % have persisting ADHD symptoms. ADHD as an early manifesting neurodevelopmental disorder is considered a major risk factor for the development of comorbid psychiatric disorders in later life. Particularly, personality disorders are oftentimes observed in adult patients suffering from ADHD. If ADHD and personality disorders share common etiological mechanisms and/or if ADHD as a severely impairing condition influences psychological functioning and learning and leads to unfavorable learning histories is unclear. The development of inflexible and dysfunctional beliefs on the basis of real and perceived impairments or otherness due to the core symptoms of ADHD is intuitively plausible. Such beliefs are a known cause for the development of personality disorders. But, why some personality disorders are more frequently found in ADHD patients as for example antisocial and borderline personality disorder remains subject of debate. Because of the high prevalence of ADHD and the high impact of personality disorders on daily functioning, it is important to take them into account when treating patients with ADHD. Research on the developmental trajectories leading to personality disorders in adult ADHD patients might open the door for targeted interventions to prevent impairing comorbid clinical pictures. PMID:26893231

  5. Real-World Data on: Attention Deficit Hyperactivity Disorder Medication Side Effects.

    Science.gov (United States)

    Cascade, Elisa; Kalali, Amir H; Wigal, Sharon B

    2010-04-01

    In this article, we provide information on patient-reported side effects from a cross-section of real-world patients. Specifically, data on side effects were tabulated for patients taking one of the following attention deficit hyperactivity disorder medications: amphetamine and dextroamphetamine; atomoxetine; dexmethylphenidate; isdexamfetamine; and methylphenidate. Forty-eight percent of the approximately 325 patients surveyed reported having experienced a side effect as a result of taking an attention deficit hyperactivity disorder medication. Most common side effects mentioned included loss of appetite, sleep problems, and mood disturbances. Only 21 percent of side effects were considered very bothersome or extremely bothersome. Regardless of how bothersome the side effects were, only 20 percent of patients mentioned the side effects to their prescribing physicians. PMID:20508803

  6. Helping adolescents with attention-deficit/ hyperactivity disorder transition toward adulthood.

    Science.gov (United States)

    Gotlieb, Edward M; Gotlieb, Jaquelin S

    2009-04-01

    Pediatricians can help adolescents with attention-deficit/hyperactivity disorder prepare to enter post-high school training and the workforce. In this article peer-reviewed studies and other resources for informing patients of the issues ahead are identified. We discuss preventive counseling, including long-term monitoring, adherence to treatment, driving, tobacco, alcohol, and other drug usage, career planning, and intimacy. The current status of insurance coverage for young adults and federal programs to assist students with attention-deficit/hyperactivity disorder are reviewed also. Consideration is given for applying for precollege testing and college accommodations and traveling abroad with medications. Pediatricians and young adults are directed to Web-based and other self-management information and tools. PMID:19492699

  7. Disordered sleep in pediatric patients with attention deficit hyperactivity disorder: an overview.

    Science.gov (United States)

    Ganelin-Cohen, Esther; Ashkenasi, Arie

    2013-11-01

    There is a well-established correlation between sleep disturbances and attention deficit hyperactivity disorder (ADHD). A large number of pediatric patients diagnosed with ADHD have sleep problems, while patients with sleep disturbances often display behavioral patterns that resemble some features of ADHD. Despite these observations, the relationship between sleep problems and ADHD is not yet fully understood. It is often difficult to pinpoint which of the disorders is the primary and which a byproduct of the other. A complicating factor is that stimulant medication such as methylphenidate, a drug of choice for ADHD, may adversely affect sleep quality in ADHD patients. However, there have also been reports that it may actually improve sleep quality. This review examines the latest trends in the contemporary literature on this clinical dilemma. PMID:24511653

  8. The Relationship between Childhood Attention Deficit/Hyperactivity Disorder and Adulthood Borderline Personality Disorder

    Directory of Open Access Journals (Sweden)

    Ali Mashhadi

    2013-02-01

    Full Text Available Background: Attention Deficit Hyperactivity Disorder (ADHD is a risk factor for Borderline Personality Disorder (BPD during adulthood. Studying the relationship between childhood ADHD disorder symptoms and depression and borderline personality disorder symptoms among students was the main aim of this study. Materials and Methods: A total of 291 students, who were studying in Shiraz and Tabriz universities inThe academic year of 2010-2011, were selected from three groups of Humanities, Basic Sciences, and Technical-Engineering Sciences using simple sampling method. They participated in the study through completing Wender Utah Rating Scale (WURS, Borderline Personality Scale (STB and Beck Depression Inventory (BDI-II. Pearsons correlation coefficient and multiple regression analysis were used to analyze the data. Results: The results showed that there is a significant positive relationship between childhood ADHD and borderline Personality Disorder (BPD in adulthood and childhood ADHD is able to predict BPD in adulthood (p<0.01. Similarly, the relationship between symptoms of childhood ADHD and depression was positive and significant (p<0.01. Conclusion: There is a relationship between symptoms of childhood ADHD, BPD and depression in students. It is recommended to pay due attention to the comorbidity disorders such as BPD and depression in the treatment of ADHD disorder.

  9. Is Attention Deficit Hyperactivity Disorder a Risk for Kohler’s Disease? Osteonecrosis of Navicular Bone of Foot

    OpenAIRE

    Basal, Ozgur; Burc, Halil; Atay, Tolga

    2015-01-01

    AbstractWe present a pediatric case report of foot pain due to Kohler's disease. We discussed the etiology and treatment of Kohler’s Disease of a 5-year-old boy who had Attention Deficit Hyperactivity Disorder in this case report. Our goal is elucidate the etiology of these cases and their relationship with behavioral disorders. Key Words: Osteonecrosis of Navicula; Kohler Disease; Attention Deficit Hyperactivity Disorder (ADHD), Trauma

  10. Attention deficit hyperactivity disorder and disordered eating behaviors: links, risks, and challenges faced.

    Science.gov (United States)

    Ptacek, Radek; Stefano, George B; Weissenberger, Simon; Akotia, Devang; Raboch, Jiri; Papezova, Hana; Domkarova, Lucie; Stepankova, Tereza; Goetz, Michal

    2016-01-01

    Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists in adulthood. It is defined by inattention and/or hyperactivity-impulsivity. ADHD is associated with many comorbidities, including eating disorders (EDs). In the last decade, studies have reported that ADHD is linked with binge EDs, bulimia nervosa, and anorexia nervosa. Many postulates have been proposed to explain the association: 1) impulsive behavior in ADHD patients leads to disordered eating behavior; 2) other psychologic comorbidities present in ADHD patients account for eating behavior; 3) poor eating habits and resulting nutritional deficiencies contribute to ADHD symptoms; and 4) other risk factors common to both ADHD and EDs contribute to the coincidence of both diseases. Additionally, sex differences become a significant issue in the discussion of EDs and ADHD because of the higher incidence of bulimia nervosa and anorexia nervosa in females and the ability of females to mask the symptoms of ADHD. Interestingly, both EDs and ADHD rely on a common neural substrate, namely, dopaminergic signaling. Dopaminergic signaling is critical for motor activity and emotion, the latter enabling the former into a combined motivated movement like eating. This linkage aids in explaining the many comorbidities associated with ADHD. The interconnection of ADHD and EDs is discussed from both a historical perspective and the one based on the revealing nature of its comorbidities. PMID:27042070

  11. Quality of life and psychomotor profile of children with attention deficit hyperactivity disorder (ADHD)

    OpenAIRE

    Juliana Barbosa Goulardins; Juliana Cristina Fernandes Bilhar Marques; Erasmo Barbante Casella

    2011-01-01

    The knowledge of psychomotor development of children with attention deficit hyperactivity disorder (ADHD) may help in defining therapeutic approaches in order to minimize losses in their quality of life. The study objectives were to evaluate the quality of life and psychomotor profile of children with ADHD and check your correlation. Fourteen children, from seven to ten years, with ADHD combined type were evaluate using the scales PedsQL™ and Motor Development Scale. Results showed adverse ef...

  12. Treatment planning for children with attention-deficit/hyperactivity disorder: treatment utilization and family preferences

    OpenAIRE

    Brinkman, William B.; Epstein, Jeffery N.

    2011-01-01

    William B Brinkman, Jeffery N EpsteinDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USABackground: Attention-deficit/hyperactivity disorder (ADHD) is a common condition that often results in child and family functional impairments. Although there are evidence-based treatment modalities available, implementation of and persistence with treatment plans vary with patients. Family preferences also vary...

  13. Maternal Depression Predicts Maternal Use of Corporal Punishment in Children with Attention-Deficit / Hyperactivity Disorder

    OpenAIRE

    Shin, Dong-Won; Stein, Mark A.

    2008-01-01

    Purpose We sought to determine if maternal depression contributed to the use of corporal punishment in children with attention-deficit/hyperactivity disorder (ADHD). Patients and Methods The data were gathered through chart review of clinic-referred children with ADHD and their mothers who were evaluated at a psychiatric clinic located in a large academic medical center in Seoul, Korea. Daily records kept by parents and 13 items from the Physical Assault of the Parent-Child Conflict Tactics S...

  14. Attention deficit hyperactivity disorder: reframing “deficit” as creative strength

    OpenAIRE

    Beaven, Alexandra

    2012-01-01

    Creative ideas are those that are both novel and useful. Creativity is considered to be a valuable social resource, which has supported the development of society in myriad domains. It has been suggested that behavioural indicators of creativity overlap with symptoms of Attention Deficit Hyperactivity Disorder (ADHD). Indeed, there is some preliminary evidence to suggest that individuals with ADHD may be more creative than individuals without ADHD. The first chapter of this thesis outlines th...

  15. Attention Deficit Hyperactivity Disorder Like Behavioral Problems and Parenting Stress in Pediatric Allergic Rhinitis

    OpenAIRE

    Lee, Young Sik; Kim, Se Hee; You, Ji Hee; Baek, Hyung Tae; Na, Chul; Kim, Bung Nyun; Han, Doug Hyun

    2014-01-01

    Objective Previous studies have reported comorbidity of attention deficit and hyperactivity disorder (ADHD) and allergic diseases. The current study investigated ADHD like behavioral symptoms and parenting stress in pediatric allergic rhinitis. Methods Eighty-seven children (6-13 years old) with allergic rhinitis and 73 age- and sex-matched children of control group were recruited. Diagnosis and severity assessments of allergic rhinitis were determined by a pediatric allergist. The Parenting ...

  16. Perceived parenting style and self-perception in children with attention deficit/hyperactivity disorder

    OpenAIRE

    Maria Fernanda Molina

    2015-01-01

    Background: there is a growing interest in the study of the self-perceptions of children with Attention Deficit/Hyperactivity Disorder (ADHD) and the bias in their self-concept. Goal: to explore how ADHD children’s perception of parenting style predicts their selfperception and the bias in self-concept. Method: Participants: children between 7 and 13 years old diagnosed with ADHD, children assisting to psychotherapy without an ADHD diagnose, and children not assisting to psychotherapy. It ...

  17. Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder

    OpenAIRE

    Waters Nicholas; Waters Susanna; Fernell Elisabeth; Forssberg Hans; Tedroff Joakim

    2006-01-01

    Abstract Background Limited data from positron emission tomography (PET) studies of subjects with attention-deficit/hyperactivity disorder (ADHD) indicate alterations in brain dopamine neurotransmission. However, these studies have used conventional univariate approaches that are less sensitive to detect complex interactions that may exist between different brain dopamine pathways and individual symptoms of ADHD. We aimed to investigate these potential interactions in adolescents with ADHD. M...

  18. Developing a model of occupational therapy practice for children with attention deficit hyperactivity disorder (ADHD)

    OpenAIRE

    Chu, Sidney Kin Hoi

    2005-01-01

    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 15/06/2005. This three-stage study led to the development of a delineation model of occupational therapy practice for children with Attention Deficit Hyperactivity Disorder (ADHD). Stage one explored the current practice of occupational therapy in the United Kingdom (UK) by conducting a national survey of 282 paediatric occupational therapists. Results indicated that there were only a small n...

  19. Neurocognitive Profile of Children with Attention Deficit Hyperactivity Disorders (ADHD): A comparison between subtypes

    OpenAIRE

    Nastaran Ahmadi; Mohammad Reza Mohammadi; Seyed Mohsen Araghi; Hadi Zarafshan

    2014-01-01

    Objective The aim of this study was to examine the differences between ADHD subtypes in executive function tasks compared to themselves and normal controls. Method In this study, 45 school aged children with Attention Deficit Hyperactivity Disorder (ADHD) and 30 normal children who were matched based on age and IQ score in Wechsler Intelligence Scale for Children-Revised (WISC-R) were compared in terms of executive function. We used Wisconsin Sorting Card Test to assess executive function in ...

  20. Meta-analysis of genome-wide association studies of attention deficit/hyperactivity disorder

    OpenAIRE

    Neale, Benjamin M.; Medland, Sarah E.; Ripke, Stephan; Asherson, Philip; Franke, Barbara; Lesch, Klaus-Peter; Faraone, Stephen V.; Nguyen, Thuy Trang; Schaefer, Helmut; Holmans, Peter; Daly, Mark; STEINHAUSEN, HANS-CHRISTOPH; Freitag, Christine,; Reif, Andreas; Tobias J Renner

    2010-01-01

    Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of existing studies to boost statistical power. Method: We used data from four projects: a) the Children's Hospital of Philadelphia (CHOP); b) phase I of ...

  1. Case-control genome-wide association study of attention-deficit/hyperactivity disorder

    OpenAIRE

    Neale, Benjamin M.; Medland, Sarah; Ripke, Stephan; Anney, Richard JL; Asherson, Philip; Buitelaar, Jan; Franke, Barbara; Gill, Michael; Kent, Lindsey; Holmans, Peter; Middleton, Frank; Thapar, Anita; Lesch, Klaus-Peter; Faraone, Stephen V.; Daly, Mark

    2010-01-01

    Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. Thus additional genomewide association studies (GWAS) are needed. Method: We used case-control analyses of 896 cases with DSM-IV ADHD genotvped using the Affymetrix 5.0 array and 2,455 repository controls screened for psychotic and bipolar symptoms genotyped using Affy...

  2. Improving the Dictation in Attention Deficit Hyperactivity Disorder by Using Computer Based Interventions: A Clinical Trial

    OpenAIRE

    Mahdi Tehranidoost; Anahita Basirnia; Shervin Assari; Mohammad Reza Mohammadi; Mostafa Najafi; Javad Alaghband-rad

    2006-01-01

    Objective: The aim of the current study was to assess the impact of computer games and computer-assisted type instruction on dictation scores of elementary school children with attention deficithyperactivity disorder (ADHD). Method: In this single-blind clinical trial, 37 elementary school children with ADHD, selected by convenience sampling and divided into group I (n=17) and group II (n=20), underwent eight one-hour sessions (3 sessions per week) of intervention by computer games versus ...

  3. Treatment of attention deficit hyperactivity disorder insomnia with blue wavelength light-blocking glasses

    OpenAIRE

    Fargason, Rachael

    2013-01-01

    Rachel E Fargason, Taylor Preston, Emily Hammond, Roberta May, Karen L GambleDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USABackground: The aim of this study was to examine a nonmedical treatment alternative to medication in attention deficit hyperactivity disorder (ADHD) insomnia, in which blue wavelength light-blocking glasses are worn during the evening hours to counteract the phase-delaying effect of light. ...

  4. The Safety and Efficacy of Methylphenidate and Dexmethylphenidate in Adults with Attention Deficit/Hyperactivity Disorder

    OpenAIRE

    Michael A. Sopko Jr; Harjeet Caberwal; Benjamin Chavez

    2010-01-01

    Objective To review the literature on the safety and efficacy of methylphenidate, OROS-methylphenidate, methylphenidate ER, and dexmethylphenidate in adults with Attention-Deficit/Hyperactivity Disorder (ADHD). To analyze the effects of different doses of methylphenidate, it’s various formulations, and methylphenidate on efficacy and safety in this population. Data sources Literature retrieval was performed through Pubmed/MEDLINE (Up to May 2010) using the terms methylphenidate, dexmethylphen...

  5. Real-World Data on: Attention Deficit Hyperactivity Disorder Medication Side Effects

    OpenAIRE

    Cascade, Elisa; Kalali, Amir H.; Wigal, Sharon B.

    2010-01-01

    In this article, we provide information on patient-reported side effects from a cross-section of real-world patients. Specifically, data on side effects were tabulated for patients taking one of the following attention deficit hyperactivity disorder medications: amphetamine and dextroamphetamine; atomoxetine; dexmethylphenidate; isdexamfetamine; and methylphenidate. Forty-eight percent of the approximately 325 patients surveyed reported having experienced a side effect as a result of taking a...

  6. Risperidone Versus Methylphenidate in Treatment of Preschool Children With Attention-Deficit Hyperactivity Disorder

    OpenAIRE

    Arabgol, Fariba; Panaghi, Leily; Nikzad, Vahid

    2015-01-01

    Background: Attention Deficit Hyperactivity Disorder (ADHD) is a common psychiatric diagnosis among preschool children. Objectives: The aim of this study was to examine the Risperidone treatment compared to Methylphenidate (MPH) in preschool children with ADHD. Patients and Methods: Thirty three outpatient preschool children, aged 3-6 years, diagnosed with ADHD (The diagnosis of ADHD was established by two child and adolescent psychiatrists according to the DSM-IV-TR criteria), participated i...

  7. Comorbidities and Costs of Adult Patients Diagnosed with Attention-Deficit Hyperactivity Disorder

    OpenAIRE

    Kristina Secnik; Andrine Swensen; Lage, Maureen J

    2005-01-01

    Introduction: The purpose of this retrospective study was to examine the prevalence of comorbidities, resource use, direct medical costs, and the costs associated with missed work for adults diagnosed with attention-deficit hyperactivity disorder (ADHD). Study design: From a large claims database that captures inpatient, outpatient and prescription drug services, individuals diagnosed with ADHD between the years 1999 and 2001 were retrospectively identified. The ADHD cohort (n = 2252) were ma...

  8. Understanding Discipline in Families of Children with Attention-Deficit/Hyperactivity Disorder: A Structural Equation Model

    OpenAIRE

    Miranda Casas, Ana; Grau, Dolores; Rosel, Jesus; Meliá, Amanda

    2009-01-01

    One hundred and fifty-five mothers of children with attention deficit/hyperactivity disorder (ADHD) completed a semi-structured interview, the Parenting Stress Index Questionnaire (Abidin, 1990), to evaluate parenting stress. The Parenting Scale (Arnold, O’Leary, Wolff & Acker, 1993) was also administered to measure dysfunctional discipline strategies. Structural equation modeling was used to test a model in which the independent variables were the Child’s Characteristics and t...

  9. Attention-Deficit/Hyperactivity Disorder: Presentation and Management in the Haitian American Child

    OpenAIRE

    Prudent, Nicole; Johnson, Peggy; Carroll, Jennifer; Culpepper, Larry

    2005-01-01

    A case study of a young Haitian American is presented that is illustrative of cultural issues that influence care of those with attention-deficit/hyperactivity disorder (ADHD). Medications are the preferred treatment for ADHD and can be combined with psychological intervention. However, many Haitians and Haitian Americans see psychoactive medications as leading to substance abuse or mental illness. Efficacious psychosocial treatments include contingency management, parent training, and behavi...

  10. Resting State Functional Connectivity Correlates of Inhibitory Control in Children with Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    MaartenMennes; F. XavierCastellanos; Milham, Michael P.

    2012-01-01

    Motor inhibition is among the most commonly studied executive functions in Attention-Deficit/Hyperactivity Disorder (ADHD). Imaging studies using probes of motor inhibition such as the Stop Signal Task (SST) consistently demonstrate ADHD-related dysfunction within a right-hemisphere fronto-striatal network that includes inferior frontal gyrus and pre-supplementary motor area (pre-SMA). Beyond findings of focal hypo- or hyper-function, emerging models of ADHD psychopathology highlight disease-...

  11. Cortical Gray Matter in Attention-Deficit/Hyperactivity Disorder: A Structural Magnetic Resonance Imaging Study

    OpenAIRE

    Batty, Martin J; Liddle, Elizabeth B.; Pitiot, Alain; Toro, Roberto; Groom, Madeleine J.; Scerif, Gaia; Liotti, Mario; Peter F Liddle; Paus, Tomáš; Hollis, Chris

    2010-01-01

    Objective Previous studies have shown smaller brain volume and less gray matter in children with attention-deficit/hyperactivity disorder (ADHD). Relatively few morphological studies have examined structures thought to subserve inhibitory control, one of the diagnostic features of ADHD. We examined one such region, the pars opercularis, predicting a thinner cortex of the inferior frontal gyrus (IFG) in children with ADHD. Method Structural images were obtained from 49 children (24 control; 25...

  12. Examining Relationships Between Executive Functioning and Delay Aversion in Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Karalunas, Sarah L.; Huang-Pollock, Cynthia L.

    2011-01-01

    Although motivation and cognition are often examined separately, recent theory suggests that a delay-averse motivational style may negatively impact development of executive functions (EFs), such as working memory (WM) and response inhibition (RI) for children with Attention Deficit Hyperactivity Disorder (ADHD; Sonuga-Barke, 2002). This model predicts that performance on delay aversion and EF tasks should be correlated for school-age children with ADHD. However, tests of these relationships ...

  13. Selective effects of methylphenidate in attention deficit hyperactivity disorder: A functional magnetic resonance study

    OpenAIRE

    Vaidya, Chandan J.; Austin, Glenn; Kirkorian, Gary; Ridlehuber, Hugh W.; Desmond, John E.; Glover, Gary H.; Gabrieli, John D. E.

    1998-01-01

    Functional MRI revealed differences between children with Attention Deficit Hyperactivity Disorder (ADHD) and healthy controls in their frontal–striatal function and its modulation by methylphenidate during response inhibition. Children performed two go/no-go tasks with and without drug. ADHD children had impaired inhibitory control on both tasks. Off-drug frontal–striatal activation during response inhibition differed between ADHD and healthy children: ADHD children had greater frontal activ...

  14. Hyperresponsiveness to social rewards in children and adolescents with attention-deficit/hyperactivity disorder (ADHD)

    OpenAIRE

    Herpertz-Dahlmann Beate; Kohls Gregor; Konrad Kerstin

    2009-01-01

    Abstract Background Current research suggests that attention-deficit/hyperactivity disorder (ADHD) is associated with larger behavioral sensitivity to reinforcement contingencies. However, most studies have focused thus far on the enhancing effects of tangible rewards such as money, neglecting that social-emotional stimuli may also impact task performance in ADHD patients. Methods To determine whether non-social (monetary) and social (positive facial expressions) rewards differentially improv...

  15. Psychometric evaluation of the Sheehan Disability Scale in adult patients with attention-deficit/hyperactivity disorder

    OpenAIRE

    Coles T; Coon C; DeMuro C; McLeod L; Gnanasakthy A

    2014-01-01

    Theresa Coles,1 Cheryl Coon,1 Carla DeMuro,1 Lori McLeod,1 Ari Gnanasakthy21Patient-Reported Outcomes, RTI Health Solutions, Research Triangle Park, NC, 2Novartis Pharmaceuticals, East Hanover, NJ, USAAbstract: Inattention and impulsivity symptoms are common among adults with attention-deficit/hyperactivity disorder (ADHD), which can lead to difficulty concentrating, restlessness, difficulty completing tasks, disorganization, impatience, and impulsiveness. Many adults with ADHD find it diffic...

  16. Gender and Conduct Problems Predict Peer Functioning among Children with Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Mikami, Amori Yee; Lorenzi, Jill

    2011-01-01

    Children with Attention-Deficit/Hyperactivity Disorder (ADHD) often have poor relationships with peers. However, research on this topic has predominantly focused on boys. This study considered child gender, ADHD status, and dimensionally-assessed conduct problems as predictors of peer relationship difficulties. Participants were 125 children (ages 6–10; 67% male), 63 with clinical diagnoses of ADHD and 62 non-ADHD comparison youth. Conduct problems were reported by teachers and observed in a ...

  17. Additional Brain Functional Network in Adults with Attention-Deficit/Hyperactivity Disorder: A Phase Synchrony Analysis

    OpenAIRE

    Yu, Dongchuan

    2013-01-01

    We develop a method to construct a new type of functional networks by the usage of phase synchrony degree that is different from the widely used Pearson's correlation approach. By a series of very strict statistical tests, we found that there is an additional network in attention-deficit/hyperactivity disorder (ADHD) subjects, superimposing the original (normal) brain functional network corresponding to healthy controls. The additional network leads to the increase in clustering coefficient, ...

  18. Methylphenidate for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

    DEFF Research Database (Denmark)

    Storebø, Ole J; Simonsen, Erik; Gluud, Christian

    2016-01-01

    CLINICAL QUESTION: Is treatment with methylphenidate associated with benefits or harms for children and adolescents with attention-deficit/hyperactivity disorder (ADHD)? BOTTOM LINE: Methylphenidate is associated with improvement in ADHD symptoms, general behavior, and quality of life; however, due...... to the very low quality of the evidence, the magnitude of the associated improvement is uncertain. Methylphenidate was associated with an increased risk of nonserious adverse events. There are too few data to assess the association with serious adverse events....

  19. Prevalence and correlates of attention-deficit hyperactivity disorder symptoms in Korean college students

    OpenAIRE

    Kwak YS; Jung YE; Kim MD

    2015-01-01

    Young-Sook Kwak, Young-Eun Jung, Moon-Doo Kim Department of Psychiatry, School of Medicine, Jeju National University, Jeju, South Korea Background: Attention-deficit hyperactivity disorder (ADHD) persists into adulthood in a high proportion of cases, causing social difficulties and affective problems. We evaluated the prevalence of symptoms of ADHD and the correlates thereof in Korean college students. Methods: A total of 2,172 college students, stratified to reflect geographical d...

  20. CLUSTER TAXOMETRY OF ATTENTION DEFICIT/ HYPERACTIVITY DISORDER WITH LATENT CLASS AND CORRESPONDENCE ANALYSIS

    OpenAIRE

    David A. Pineda; DANIEL CAMILO AGUIRRE-ACEVEDO; FRANCISCO LOPERA; DANIEL A PINEDA; MAURICIO ARCOS-BURGOS

    2007-01-01

    Attention deficit/hyperactivity disorder (ADHD) has heterogeneous symptoms with diverse grades of severity. Latentclass cluster analysis (LCCA) can be used to classify children, using direct data from any instrument that reports thesesymptoms, without previous gold standard diagnosis. One ADHD symptoms checklist, and one ADHD comorbiditiesquestionnaire were used. LCCAs were developed for each instrument, which were administered to a sample of 540children and adolescents, aged 4-17 years, from...

  1. Association of Adult Attention Deficit/Hyperactivity Disorder and Traffic Injuries in Tabriz - Iran

    OpenAIRE

    Arash Jodeiri Eslami; Homayon Sadeghi-Bazargani; Fatemeh Ranjbar; Shahrokh Amiri; Amir mohammad Navali; Farnaz Saedi

    2011-01-01

    "nObjective: Nowadays, it is well known that the attention-deficit/hyperactivity disorder (ADHD) is not confined to children and adolescents. Recent data showed that a considerable portion of the general adult population may be affected by ADHD. On the other hand, the impact of ADHD on driving performance, a major area of adult life, has gained enthusiasm. More recent studies revealed an association between adult ADHD and undesirable driving problems. This study was performed to determine the...

  2. Diagnosis, treatment, and burden of illness among adults with attention-deficit/hyperactivity disorder in Europe

    OpenAIRE

    Stephen L. Able

    2014-01-01

    Stephen L Able,1 Virginia Haynes,1 Jihyung Hong2 1Eli Lilly and Company, Indianapolis, IN, USA; 2Eli Lilly and Company, Windlesham, UK Purpose: To quantitatively address the burden of attention-deficit/hyperactivity disorder (ADHD) in Europe (Germany, the UK, Sweden, Denmark, and the Netherlands), to describe adult experience leading to diagnosis and treatment of ADHD, and to compare those findings with results from the US. Survey respondents and methods: Data were collected from an internat...

  3. Management of adult attention deficit hyperactivity disorder in UK primary care: a survey of general practitioners

    OpenAIRE

    McCarthy, Suzanne; Wilton, Lynda; Murray, Macey; Hodgkins, Paul; Asherson, Philip; Wong, Ian CK

    2013-01-01

    Background Compared to existing literature on childhood attention deficit hyperactivity disorder (ADHD), little published adult data are available, particularly outside of the United States. Using General Practitioner (GP) questionnaires from the United Kingdom, this study aimed to examine a number of issues related to ADHD in adults, across three cohorts of patients, adults who received ADHD drug treatment in childhood/adolescence but stopped prior to adulthood; adults who received ADHD drug...

  4. Tobacco Smoking in Individuals with Attention-Deficit/Hyperactivity Disorder: Epidemiology and Pharmacological Approaches to Cessation

    OpenAIRE

    Gray, Kevin M.; Upadhyaya, Himanshu P.

    2009-01-01

    The co-occurrence of Attention-Deficit/Hyperactivity Disorder (ADHD) and Nicotine Dependence is common. Individuals with ADHD are more likely to initiate smoking and become dependent on nicotine than their non-ADHD counterparts, and recent evidence suggests that they may have more difficulty quitting smoking. Little is known about how to best approach treating these co-morbidities to optimize clinical outcome. Clinicians treating individuals with either ADHD or Nicotine Dependence should be a...

  5. Underdiagnosis of Attention-Deficit/Hyperactivity Disorder in Adult Patients: A Review of the Literature

    OpenAIRE

    Ginsberg, Ylva; Quintero, Javier; Anand, Ernie; Casillas, Marta; Upadhyaya, Himanshu P.

    2014-01-01

    Objective: To raise awareness of attention-deficit/hyperactivity disorder (ADHD) as an underdiagnosed, undertreated, often comorbid, and debilitating condition in adults. Data Sources: PubMed was searched using combinations of keywords, including ADHD, adult, diagnosis, identify, prevalence, and comorbid, to find articles published between 1976 and 2013. Study Selection: In total, 99 articles were selected for inclusion on the basis of their relevance to the objective and importance to and re...

  6. Emerging Support for a Role of Exercise in Attention-Deficit/Hyperactivity Disorder Intervention Planning

    OpenAIRE

    Berwid, Olga G.; Halperin, Jeffrey M.

    2012-01-01

    Recent years have seen an expansion of interest in non-pharmacological interventions for attention-deficit/hyperactivity disorder (ADHD). Although considerable treatment development has focused on cognitive training programs, compelling evidence indicates that intense aerobic exercise enhances brain structure and function, and as such, might be beneficial to children with ADHD. This paper reviews evidence for a direct impact of exercise on neural functioning and preliminary evidence that exer...

  7. Study protocol: the sleeping sound with attention-deficit/hyperactivity disorder project

    OpenAIRE

    Oberklaid Frank; Mensah Fiona; Davey Margot; Gerner Bibi; Efron Daryl; Sciberras Emma; Hiscock Harriet

    2010-01-01

    Abstract Background Up to 70% of children with Attention-Deficit/Hyperactivity Disorder (ADHD) experience sleep problems including difficulties initiating and maintaining sleep. Sleep problems in children with ADHD can result in poorer child functioning, impacting on school attendance, daily functioning and behaviour, as well as parental mental health and work attendance. The Sleeping Sound with ADHD trial aims to investigate the efficacy of a behavioural sleep program in treating sleep probl...

  8. The relationship between attention deficit hyperactivity disorder and health-related physical fitness in university students

    OpenAIRE

    Jeoung, Bog Ja

    2014-01-01

    College students with a tendency toward attention deficit/hyperactivity disorder (ADHD) tend to act impulsively because they cannot control their behavior. They display low academic achievement and insufficient social skills, and are at high risk for alcoholism and drug abuse. Although various intervention methods have been used to reduce ADHD tendency (e.g., improving physical fitness and participating in sports and exercise), there are few studies on the relationship between ADHD and health...

  9. Executive Dysfunction in Children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD)

    OpenAIRE

    Javad Alaghband-Rad; Reza Rad Goodarzi; Mehdi Tehrani-Doost

    2007-01-01

    "nObjective: The purpose of this study is to compare the executive functions children and adolescents who suffer from attention deficit hyperactivity disorder "n(ADHD) with normal children. "nMethod: Twenty children with ADHD were compared to 19 healthy children terms of some executive functions using the computerized version of Tower London, Continuous Performance Test (CPT), and Stroop Color Test. "nResults: In "Tower of London", the performance of children with ADHD was "nworse than normal...

  10. Complementary and Alternative Therapies for Pediatric Attention Deficit Hyperactivity Disorder: A Descriptive Review

    OpenAIRE

    Searight, Barbara K.; Scott Perkins; Kayla Robertson; Todd Smith; H. Russell Searight

    2012-01-01

    Attention deficit hyperactivity disorder (AD/HD), characterized by impulsivity, distractibility, and inattention, has an estimated pediatric population prevalence of 6–8%. Family physicians and pediatricians evaluate and treat the majority of children with this condition. The evidence-based treatment of choice for ADHD, stimulant medication, continues to be a source of public controversy. Surveys suggest that among parents of children with ADHD, there is considerable interest in complementary...

  11. Is Attention Deficit Hyperactivity Disorder (ADHD) Symptom Severity Associated with Tobacco Use?

    OpenAIRE

    Upadhyaya, Himanshu P.; Carpenter, Matthew J.

    2008-01-01

    Several studies report a strong link between ADHD and tobacco use; however, the nature of this relationship is not entirely clear. We examined the relationship between attention deficit hyperactivity disorder (ADHD) symptoms and tobacco use within a sample of college students. Although tobacco use was the main focus, we also examined alcohol and marijuana use. We examined the association between the number of ADHD symptoms endorsed (severity), and tobacco, alcohol, and marijuana use in a conv...

  12. A cross-sectional analysis of video games and attention deficit hyperactivity disorder symptoms in adolescents

    OpenAIRE

    Rabinowitz Terry; Chan Philip A

    2006-01-01

    Abstract Background Excessive use of the Internet has been associated with attention deficit hyperactivity disorder (ADHD), but the relationship between video games and ADHD symptoms in adolescents is unknown. Method A survey of adolescents and parents (n = 72 adolescents, 72 parents) was performed assessing daily time spent on the Internet, television, console video games, and Internet video games, and their association with academic and social functioning. Subjects were high school students...

  13. Role of Parent Training in the Effective Management of Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Power, Thomas J.; Russell, Heather F.; Soffer, Stephen L.; Jessica Blom-Hoffman; Suzanne M. Grim

    2002-01-01

    Parent training can be an effective strategy for assisting children and their families to cope with attention-deficit/hyperactivity disorder (ADHD), particularly when it is used as part of a multimodal approach in combination with stimulant medication. The benefits of parent training include: cost effectiveness, particularly when applied in group formats; structured format, enabling the treatment to be applied in a relatively standardized manner across settings and providers; and its generall...

  14. Attention-Deficit / Hyperactivity Disorder (ADHD): Data and Statistics

    Science.gov (United States)

    ... States The American Psychiatric Association states in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) that 5% of children have ADHD ... without ADHD. [ Read abstract ] Footnotes: American ... Mental Disorders, Fifth edition: DSM-5. Washington: American Psychiatric Association, ...

  15. Distinguishing between attention-deficit hyperactivity and fetal alcohol spectrum disorders in children: clinical guidelines

    Directory of Open Access Journals (Sweden)

    Elizabeth Peadon

    2010-08-01

    Full Text Available Elizabeth Peadon, Elizabeth J ElliottDiscipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, AustraliaAbstract: Fetal alcohol spectrum disorders (FASD are the physical and neurodevelopmental outcomes of fetal alcohol exposure. The behavioral phenotype of children with FASD includes difficulties with executive function, memory, planning, processing speed, and attention. Although attention deficit hyperactivity disorder (ADHD is diagnosed in up to 94% of individuals with heavy prenatal alcohol exposure, the exact relationship between FASD and ADHD is unclear. There is some evidence that ADHD in FASD may be a specific clinical subtype and thus may require a different treatment approach. Although traditional behavioral observation scales may not distinguish between the two groups, there is evidence that children with FASD have a different profile on the four-factor model of attention than children with ADHD who do not have FASD. There is a paucity of good scientific evidence on effective interventions for individuals with ADHD and FASD. There is weak evidence that children with FASD and ADHD may have a better response to dexamphetamine than methylphenidate. There is a strong need for larger, high quality studies to examine the relationship between ADHD and FASD and identify effective treatments because management of inattention and hyperactivity may improve learning and ameliorate the common secondary disabilities associated with FASD.Keywords: fetal alcohol spectrum disorders, attention deficit hyperactivity disorder

  16. Animal models of attention-deficit hyperactivity disorder

    OpenAIRE

    Sagvolden Terje; Russell Vivienne A; Johansen Espen

    2005-01-01

    Abstract Although animals cannot be used to study complex human behaviour such as language, they do have similar basic functions. In fact, human disorders that have animal models are better understood than disorders that do not. ADHD is a heterogeneous disorder. The relatively simple nervous systems of rodent models have enabled identification of neurobiological changes that underlie certain aspects of ADHD behaviour. Several animal models of ADHD suggest that the dopaminergic system is funct...

  17. Attention-Deficit / Hyperactivity Disorder (ADHD): Symptoms and Diagnosis

    Science.gov (United States)

    ... needed for younger children. Reference American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 5th edition. Arlington, VA., American Psychiatric Association, 2013. ...

  18. Attentional control and subjective executive function in treatment-naive adults with Attention Deficit Hyperactivity Disorder.

    Directory of Open Access Journals (Sweden)

    Venke Arntsberg Grane

    Full Text Available We investigated performance-derived measures of executive control, and their relationship with self- and informant reported executive functions in everyday life, in treatment-naive adults with newly diagnosed Attention Deficit Hyperactivity Disorder (ADHD; n = 36 and in healthy controls (n = 35. Sustained attentional control and response inhibition were examined with the Test of Variables of Attention (T.O.V.A.. Delayed responses, increased reaction time variability, and higher omission error rate to Go signals in ADHD patients relative to controls indicated fluctuating levels of attention in the patients. Furthermore, an increment in NoGo commission errors when Go stimuli increased relative to NoGo stimuli suggests reduced inhibition of task-irrelevant stimuli in conditions demanding frequent responding. The ADHD group reported significantly more cognitive and behavioral executive problems than the control group on the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A. There were overall not strong associations between task performance and ratings of everyday executive function. However, for the ADHD group, T.O.V.A. omission errors predicted self-reported difficulties on the Organization of Materials scale, and commission errors predicted informant reported difficulties on the same scale. Although ADHD patients endorsed more symptoms of depression and anxiety on the Achenbach System of Empirically Based Assessment (ASEBA than controls, ASEBA scores were not significantly associated with T.O.V.A. performance scores. Altogether, the results indicate multifaceted alteration of attentional control in adult ADHD, and accompanying subjective difficulties with several aspects of executive function in everyday living. The relationships between the two sets of data were modest, indicating that the measures represent non-redundant features of adult ADHD.

  19. Children and Adults with Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    ... All Rights Reserved. Press Privacy Attention Magazine Archives Advertise with CHADD Contact Us Site Map Report a Problem For help call: 800-233-4050 Follow CHADD on Facebook Follow CHADD on Twitter

  20. Attention Deficit Hyperactivity Disorder in a Patient With Congenital Mirror Movement Disorder and Colpocephaly

    Directory of Open Access Journals (Sweden)

    Selcen Yaroglu Kazanci

    2015-10-01

    Full Text Available Introduction: Congenital mirror movement disorder designates involuntary movements on one side of the body that occur as mirror of the intentional movements on the contralateral side. Colpocephaly is described as persistence of fetal configuration of lateral ventricles. Case Presentation: A two-month old male infant was brought to the hospital due to bilateral identical movements of the hands. Except for bilateral involuntary synkinetic imitative movements in hands, neurological and physical examination was normal. Cranial MRI showed corpus callosum dysgenesis, hypogenesis and dilation of bilateral lateral ventricular posterior horns (colpocephaly. At the age of 7 years, he was started to use metylphenydate to mitigate attention deficit and hyperactivity disorder. The mirror movements were decreasing in amplitude by years and were not so serious to affect normal life activities. Conclusions: Mirror movements, diagnosed usually during childhood, may be congenital or secondary to neurological diseases. Although they generally do not affect normal life activities, in some cases severity of mirror movements causes a real debilitating disease. In our case the patient was diagnosed at the age of 2 months and on follow-up no debilitating problems were observed. This is the first case to describe the association of colpocephaly and mirror movements. The exact mechanism of this association is not known. Although it is known that mirror movements may be in relation with some pychiatric pathologies, this is the first report of attention deficit and hyperactivity disorder in conjunction with mirror movements and/or colpocephaly. Managing comorbidities, either physical or psyhchological, will help the patient to live in good health without trying to cope with other pathological diseases.

  1. Attention deficit hyperactivity disorder presenting as dermatitis artefacta

    OpenAIRE

    Suravi Patra; Chandra Sekhar Sirka

    2016-01-01

    Dermatitis artefacta, a self-inflicted intentional dermatosis is a very rare diagnosis in childhood. In a large proportion, the underlying psychiatric disorders go unidentified due to lack of collaboration between dermatologist and psychiatrist. The underlying psychological reasons for childhood dermatitis artefacta include emotional distress and interpersonal conflicts. A multitude of psychosocial factors interact to precipitate this disorder. Here, we report a child with dermatitis artefact...

  2. The Relationship between Serum Vitamin D Level and Attention Deficit Hyperactivity Disorder

    OpenAIRE

    Sharif, Mohammad Reza; Madani, Mahla; Tabatabaei, Fatemeh; TABATABAEE, Zakieh

    2015-01-01

    Objective Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent mental health disorders. In recent years, the impacts of various micronutrients on ADHD have been studied. However, vitamin D has received much less attention. This study was aimed at evaluating the association and level of serum vitamin D in children with ADHD. Materials & Methods This case-control study was carried out, in 2012, on 6 to 12 yr-old children. Thirty-seven were children with ADHD in the cases...

  3. Evaluation of Planning Dysfunction in Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorders Using the Zoo Map Task

    Science.gov (United States)

    Salcedo-Marin, M. D.; Moreno-Granados, J. M.; Ruiz-Veguilla, M.; Ferrin, M.

    2013-01-01

    Attention-Deficit-Hyperactivity-Disorders (ADHD) and Autistic-Spectrum-Disorders (ASD) share overlapping clinical and cognitive features that may confuse the diagnosis. Evaluation of executive problems and planning dysfunction may aid the clinical diagnostic process and help disentangle the neurobiological process underlying these conditions. This…

  4. Methylphenidate in the Treatment of Children and Adolescents with Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Findling, Robert L.; Short, Elizabeth J.; McNamara, Nora K.; Demeter, Christine A.; Stansbrey, Robert J.; Gracious, Barbara L.; Whipkey, Resaca; Manos, Michael J.; Calabrese, Joseph R.

    2007-01-01

    The short-term efficacy of methylphenidate in the treatment of youths aged 5 to 17 years with bipolar disorder (BD) and comorbid attention deficit/hyperactivity disorder (ADHD) was investigated. The trial observation showed that euthymic youths with BD and ADHD might benefit from short-term concomitant treatment with methylphenidate.

  5. Anxiety and Depression Symptoms in Children with Asperger Syndrome Compared with Attention-Deficit/Hyperactivity Disorder and Depressive Disorder

    Science.gov (United States)

    Park, Subin; Park, Min-Hyeon; Kim, Hyo Jin; Yoo, Hee Jeong

    2013-01-01

    The objective of this study was to examine (a) anxiety and depression symptoms in children with Asperger syndrome (AS) compared to children with attention-deficit/hyperactivity disorder (ADHD) and children with depressive disorder; (b) parental anxiety and depressive symptoms in the three groups; and (c) the association between the anxiety and…

  6. Support for Learning Goes beyond Academic Support: Voices of Students with Asperger's Disorder and Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Bolic Baric, Vedrana; Hellberg, Kristina; Kjellberg, Anette; Hemmingsson, Helena

    2016-01-01

    The purpose of this study was to describe and explore the experiences of support at school among young adults with Asperger's disorder and attention deficit hyperactivity disorder and also to examine what support they, in retrospect, described as influencing learning. Purposive sampling was used to enroll participants. Data were collected through…

  7. Intervention strategies in children with cochlear implants having attention deficit hyperactivity disorder.

    Science.gov (United States)

    Pundir, Munish; Nagarkar, Anu N; Panda, Naresh K

    2007-06-01

    Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood which not only affects child's education, development and peer functioning but is also associated with significant morbidity in areas of social and academic success. ADHD may hamper the language acquisition in hearing impaired children. When such children are scheduled for the auditory verbal therapy following cochlear implantation, the outcome is limited due to reduced attention span. We have presented two cases who had undergone cochlear implantation and showed the signs of ADHD. As there was little progress in listening skills and speech and language acquisition following 3 months of therapy, both children were referred to Psychiatry Department and were diagnosed as having ADHD. Following little improvement with behavior modification techniques, they were put on medication. Significant improvement was noticed with reduction in hyperactivity and increased attention span after the administration of the drugs. PMID:17391776

  8. Multimodal MR Imaging of Brain Iron in Attention Deficit Hyperactivity Disorder: A Noninvasive Biomarker That Responds to Psychostimulant Treatment?

    OpenAIRE

    Adisetiyo, Vitria; Jensen, Jens H.; Tabesh, Ali; Deardorff, Rachael L.; Fieremans, Els; Di Martino, Adriana; Gray, Kevin M.; Castellanos, Francisco X; Helpern, Joseph A.

    2014-01-01

    Our results implicate reduced striatal and thalamic brain iron levels in attention deficit hyperactivity disorder pathophysiology before medication and suggest that reduced brain iron levels may normalize with psychostimulant treatment.

  9. Methylphenidate significantly improves driving performance of adults with attention-deficit hyperactivity disorder: a randomized crossover trial.

    NARCIS (Netherlands)

    Verster, J.C.; Bekker, E.M.; Roos, M.; Minova, A.; Eijken, E.J.; Kooij, J.J.; Buitelaar, J.K.; Kenemans, J.L.; Verbaten, M.N.; Olivier, B.; Volkerts, E.R.

    2008-01-01

    Although patients with attention-deficit hyperactivity disorder (ADHD) have reported improved driving performance on methylphenidate, limited evidence exists to support an effect of treatment on driving performance and some regions prohibit driving on methylphenidate. A randomized, crossover trial e

  10. MR imaging of the effects of methylphenidate on brain structure and function in Attention-Deficit/Hyperactivity Disorder

    NARCIS (Netherlands)

    Schweren, Lizanne J. S.; de Zeeuw, Patrick; Durston, Sarah

    2013-01-01

    Methylphenidate is the first-choice pharmacological intervention for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). The pharmacological and behavioral effects of methylphenidate are well described, but less is known about neurochemical brain changes induced by methylphenidate. Thi

  11. Attention Deficit Hyperactivity Disorder (ADHD) in Childhood Epilepsy

    Science.gov (United States)

    Reilly, Colin J.

    2011-01-01

    ADHD and epilepsy common are both common childhood disorders and both can have significant negative consequences on a child's behavioural, learning, and social development. Both conditions can co-occur and population studies suggest that the prevalence of ADHD in childhood epilepsy is between 12 and 17%. The prevalence of epilepsy in ADHD is lower…

  12. [Mindfulness-based intervention in attention-deficit-/hyperactivity disorder (ADHD)].

    Science.gov (United States)

    Schmiedeler, Sandra

    2015-03-01

    This paper reviews the current literature on mindfulness-based interventions in the treatment of attention-deficit/hyperactivity disorder (ADHD). Mindfulness means paying attention and being aware of the experiences occurring in the present moment, and it is usually developed by the practice of meditation. Research shows that mindfulness training is associated with improved attention systems and self-regulation, and that it therefore fosters those skills that are underdeveloped in individuals with ADHD. Although only few studies have investigated the effectiveness of mindfulness training in ADHD (many of which showing methodological limitations), the findings do suggest that mindfulness may be useful in ADHD interventions. PMID:25769764

  13. Reconsidering "inattention" in attention-deficit hyperactivity disorder: implications for neuropsychological assessment and intervention.

    Science.gov (United States)

    Carmichael, Jessica A; Kubas, Hanna A; Carlson, Helen L; Fitzer, Kim R; Wilcox, Gabrielle; Lemay, Jean-François; Bray, Signe; MacMaster, Frank P; Hale, James B

    2015-01-01

    Attention-deficit hyperactivity disorder (ADHD) does not exist. This explicit statement needs elucidation of course given ADHD is a common neurodevelopmental disorder, but it provides the reader with the impetus to reconsider long-held beliefs about this condition and its treatment. Surely, there is a disorder called ADHD from which this thesis is framed, but primary attention and hyperactivity-impulsivity problems are mediated by different albeit interrelated brain systems. Like many neurodevelopmental disorders (e.g., learning disabilities, autism spectrum disorder), the medical and psychological professions have used a single, large inclusive ADHD diagnostic category to represent children with different etiologies for their overt symptoms. Despite neurobiological differences among children diagnosed with ADHD, the clinical position that attention-deficit or primary attention problems are sufficient for ADHD identification undermines clinical practice. This commonly accepted dubious position not only undermines the diagnostic utility of our neuropsychological measures, but it attenuates treatment effects as well. Supported with evidence from our ongoing ADHD research program, this data-based review will support these contentions and provide implications for diagnosis and treatment of children with attention problems. PMID:25748971

  14. [Attention deficit disorder and hyperactivity: does the treatment affect the statural growth?].

    Science.gov (United States)

    Damiani, Durval; Damiani, Daniel; Casella, Erasmo

    2010-03-01

    The current study evaluated the influence of stimulant drugs used for attention deficit and hyperactivity (ADH) on statural growth. The authors conducted a literature review collecting published articles on attention deficit hyperactivity disorder and its relationship with short stature. The source of information was the PubMed database where the following terms were researched: "Growth and Methylphenidate"/"Attention deficit and hyperactivity versus short stature"/"Methylphenidate and growth disorders". ADH are difficult clinical situations that interfere with the patient's well-being and social and school performance. Once the diagnosis is attained stimulant medications such as methylphenidate have a key role in the treatment but there are concerns regarding their interference in growth and weight gain. We reviewed many publications regarding these side effects and there is no consensus on them; however, even when they happen to occur their intensity is not sufficient to preclude the use of the medication. We have to take into consideration the cost/benefit relationship, remembering that improvement in school and social performance are very welcome to the child and family. Careful monitoring of the growth chart can detect worsening of growth and its intensity will determine if the drug shall or shall not be interrupted. PMID:20520955

  15. Effects of Low Doses of Polyunsaturated Fatty Acids on the Attention Deficit/Hyperactivity Disorder of Children: A Systematic Review

    OpenAIRE

    Grassmann, Viviane; Santos-Galduróz, Ruth Ferreira; Galduróz, José Carlos Fernandes

    2013-01-01

    Since attention deficit/hyperactivity disorder (ADHD) presents high prevalence among children, science has been researching alternative forms of treatment that do not involve medication. Objective: To evaluate the effects of polyunsaturated fatty acids (PUFAs) on attention deficit/hyperactivity disorder. Methods: We reviewed the articles published between 1980 and 2012 indexed in the databases PubMed, APA psychNET, Scopus and Web of Knowledge. Results: Initially 231 articles were selected, ou...

  16. Memantine versus Methylphenidate in Children and Adolescents with Attention Deficit Hyperactivity Disorder: A Double-Blind, Randomized Clinical Trial

    OpenAIRE

    MohammadReza Mohammadi; Soleiman Mohammadzadeh; Shahin Akhondzadeh

    2015-01-01

    Objectives: The aim of this randomized clinical trial was to assess the efficacy of memantine versus methylphenidate in the treatment of children with attention deficit hyperactivity disorder.Method: Forty participants (34 boys and 6 girls) aged 6-11 who were diagnosed with attention deficit hyperactivity disorder based on (DSM-IV-TR) criteria were selected for this study. The participants were randomly assigned to two groups: group one (n = 22) received memantine and the other group (n = 18)...

  17. A randomized controlled trial investigation of a non-stimulant in attention deficit hyperactivity disorder (ACTION): Rationale and design

    OpenAIRE

    Clarke Simon D; Hermens Daniel F; Kohn Michael R; Tsang Tracey W; Richard, Clark C; Efron Daryl; Cranswick Noel; Lamb Chris; Williams Leanne M

    2011-01-01

    Abstract Background The ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized cross-over trial of the non-stimulant medication, Atomoxetine, in children and adolescents with attention deficit hyperactivity disorder (ADHD). The primary aims are to examine the efficacy of atomoxetine for improving cognition and emotional function in ADHD and whether any improvements in these outcomes are more pronoun...

  18. Mediating Effect of Depressive Symptoms on the Relationship between Adult Attention Deficit Hyperactivity Disorder and Quality of Life

    OpenAIRE

    Seo, Ji-Yeong; Lee, Cheol-Soon; Park, Chul-Soo; Kim, Bong-Jo; Cha, Bo-Seok; Lee, So-Jin; Ahn, In-Young

    2014-01-01

    Objective The aim of this study was to investigate whether depressive symptoms affect the relationship between adult attention deficit hyperactivity disorder (ADHD) and the quality of life (QOL) in Korean soldiers. Methods We evaluated past and present symptoms of adult ADHD (the Korean Adult Attention-Deficit/Hyperactivity Disorder Scale and the Wender Utah Rating Scale), depression (the Center for Epidemiological Studies Depression Scale) and QOL (the Korean version of the SmithKline Beecha...

  19. Ginkgo biloba as an adjunct to methylphenidate in the treatment of attention deficit hyperactivity disorder in children: review of articles

    OpenAIRE

    Paria Hebrani; Fatemeh Behdani; Hoda Jalayer

    2015-01-01

    Attention-deficit/hyperactivity disorder is one of the most common psychiatric disorders in childhood. The medications which inhibit the reuptake of noradrenline and dopamine including psychostimulants such as methylphenidate and dextroamphetamine and non-stimulating pre-frontal cortex noradrenaline reuptake inhibitor such as atomoxetine, are the standard treatment of ADHD. Adverse effects of stimulants have been reported in thirty percent of patients with attention-deficit/hyperactivity diso...

  20. The Relationship Between Problem Gambling and Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Waluk, O R; Youssef, G J; Dowling, N A

    2016-06-01

    Recent studies indicate that treatment-seeking problem gamblers display elevated rates of ADHD and that adolescents who screen positive for ADHD are more likely to engage in gambling, develop gambling problems, and experience a greater severity in gambling problems. This study aimed to (a) compare the prevalence of ADHD in treatment-seeking problem gamblers to the general population; (b) investigate the relationships between ADHD and problem gambling severity, cluster B personality disorders, motor impulsivity, alcohol use, substance use, gender, and age; and (c) investigate the degree to which these factors moderate the relationship between ADHD and problem gambling severity. Participants included 214 adults (154 males, 58 females, 2 unspecified) who sought treatment for their gambling problems at a specialist gambling agency in Melbourne, Australia. Almost one-quarter (24.9 %) of treatment-seeking problem gamblers screened positively for ADHD, which was significantly higher than the 14 % prevalence in a community sample. ADHD was significantly positively correlated with problem gambling severity, motor impulsivity, and cluster B personality disorders, but was not associated with alcohol and substance use, gender or age. None of the factors significantly moderated the relationship between ADHD and problem gambling severity. These findings suggest that a considerable proportion of treatment-seeking problem gamblers report ADHD and that their clinical profile is complicated by the presence of high impulsivity and cluster B personality disorders. They highlight the need for specialist gambling agencies to develop screening, assessment, and management protocols for co-occurring ADHD to enhance the effectiveness of treatment. PMID:26271807

  1. Cortical Inhibition in Attention Deficit Hyperactivity Disorder: New Insights from the Electroencephalographic Response to Transcranial Magnetic Stimulation

    Science.gov (United States)

    Bruckmann, Sarah; Hauk, Daniela; Roessner, Veit; Resch, Franz; Freitag, Christine M.; Kammer, Thomas; Ziemann, Ulf; Rothenberger, Aribert; Weisbrod, Matthias; Bender, Stephan

    2012-01-01

    Attention deficit hyperactivity disorder is one of the most frequent neuropsychiatric disorders in childhood. Transcranial magnetic stimulation studies based on muscle responses (motor-evoked potentials) suggested that reduced motor inhibition contributes to hyperactivity, a core symptom of the disease. Here we employed the N100 component of the…

  2. Neuropsychological and neurophysiological approaches to study of variants of Attention Deficit Hyperactivity Disorder

    Directory of Open Access Journals (Sweden)

    Matveyeva E. Yu.

    2012-06-01

    Full Text Available The present review carries out analysis of empirical studies concerning neuropsychological and neurophysiological mechanisms of Attention Deficit Hyperactivity Disorder (ADHD. The current data, regarding malfunctions of brain systems at various levels of aetiopathogenesis (genetic, neurotrasmitting, functioning of separate brain structure, are discussed. The article regards the character of deficit in various components of psychic activity in people with ADHD, namely, executive functions and temporary storage (working memory, activating and neurodynamic components of activity, separate operational characteristics, and motivational impairments of patients with ADHD. The possibility of disclosing some clinical variants of the ADHD syndrome, differing in mechanisms, is also discussed in the article.

  3. Attention Deficit/Hyperactivity Disorder or Attention Seeking? Ways of Distinguishing Two Common Childhood Problems

    Science.gov (United States)

    Mellor, Nigel

    2009-01-01

    Nigel Mellor recently retired from his work with the educational psychology service in North Tyneside. In this article, he proposes that attention-seeking behaviour may lead to major difficulties at home and school and indicates the ways in which recent research is beginning to clarify the area. Attention deficit disorders also cause great…

  4. Does Electroencephalography Contribute to Examining Children with Attention Deficit Hyperactivity Disorder?

    Directory of Open Access Journals (Sweden)

    Afshin FAYYAZI

    2014-07-01

    Full Text Available How to Cite This Article: Fayyazi A, Khajeh A. Does Electroencephalography Contribute to Examining Children with Attention Deficit Hyperactivity Disorder? Iran J Child Neurol. 2014 Summer;8(3: 65-67.Letter to Editor, Has not abstract.ReferencesSwaiman Kenneth F AS, Ferriero D, Schor N. Pediatric neurology: principles & practice. 5th ed. Philadelphia: Elsevier/Saunders; 2012. p.622-628.Sadock BJ, Sadock VA, Ruiz P, Kaplan HI. Kaplan & Sadock’s comprehensive textbook of psychiatry. 9th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2009.p.3560-3579.Parisi P, Moavero R, Verrotti A, Curatolo P. Attention deficit hyperactivity disorder in children with epilepsy. Brain & development. 2010;32(1:10-6. Epub 2009/04/17.Laporte N, Sebire G, Gillerot Y, Guerrini R, Ghariani S. Cognitive epilepsy: ADHD related to focal EEG discharges. Pediatric neurology. 2002;27(4:307-11. Epub 2002/11/19.Dunn DW, Kronenberger WG. Childhood epilepsy, attention problems, and ADHD: review and practical considerations. Seminars in pediatric neurology. 2005;12(4:222-8. Epub 2006/06/20.Kattimani S, Mahadevan S. Treating children with attention-deficit/hyperactivity disorder and comorbid epilepsy. Annals of Indian Academy of Neurology. 2011;14(1:9-11. Epub 2011/06/03.Holtmann M, Becker K, Kentner-Figura B, Schmidt MH. Increased frequency of rolandic spikes in ADHD children. Epilepsia. 2003;44(9:1241-4. Epub 2003/08/16.Richer LP, Shevell MI, Rosenblatt BR. Epileptiform abnormalities in children with attention-deficithyperactivity disorder. Pediatric neurology. 2002;26(2:125-9. Epub 2002/03/19.Marston D, Besag F, Binnie CD, Fowler M. Effects of transitory cognitive impairment on psychosocial functioning of children with epilepsy: a therapeutic trial. Developmental medicine and child neurology. 1993;35(7:574-81. Epub 1993/07/01.Fonseca LC, Tedrus GM, Moraes C, Vicente Machado A, Almeida MP, Oliveira DO. Epileptiform abnormalities and quantitative EEG in

  5. Alternative and controversial treatments for attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Baumgaertel, A

    1999-10-01

    ADHD is a syndrome that can be treated effectively, safely, and economically with stimulant medications. There is no equal alternative to these agents in short-term treatment of ADHD symptoms. However, many families seek alternatives to stimulants and other drug treatments for a variety of reasons. Alternative approaches reflect the complexity and heterogeneity of the disorder by being equally manifold, complex, and often obscure in their modus operandi. Scientific evidence suggests that individualized dietary management may be effective in some children. Trace element supplementation also may be beneficial when specific deficiencies are present. At this point, nootropics, herbs, and homeopathy are being seriously researched regarding their role in neurologic functioning, but evidence to support their role in the specific treatment of ADHD is inconsistent or lacking. Self-regulatory techniques such as hypnotherapy and biofeedback do not alter the core symptoms of ADHD but may be helpful in controlling secondary symptoms. These methods are unique in ADHD treatment because children can become active agents of their own coping strategies. There is no scientific evidence to support the validity of vision therapy, oculovestibular treatment, or sound training (Tomatis method) as treatment modalities for ADHD. However, auditory stimulation with individualized music may help to improve situational performance in cognitive tasks. Regardless of the treatment approach, the diagnosis of ADHD and other comorbidities first must be established through a standard medical evaluation. The standard treatment options always should be presented and discussed carefully. If alternative approaches are sought, the merits of available options should be reiterated. If the primary care provider is not comfortable or knowledgeable about an acceptable method, referral to capable and responsible practitioners in the community who are experienced in these areas should be considered. The primary

  6. Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no intervention

    DEFF Research Database (Denmark)

    Bikic, Aida; Leckman, J. F.; Lindschou, Jane; Ø. Christensen, Torben; Dalsgaard, Søren

    2015-01-01

    BACKGROUND: Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by symptoms of inattention and impulsivity and/or hyperactivity and a range of cognitive dysfunctions. Pharmacological treatment may be beneficial; however, many affected individuals...... continue to have difficulties with cognitive functions despite medical treatment, and up to 30 % do not respond to pharmacological treatment. Inadequate medical compliance and the long-term effects of treatment make it necessary to explore nonpharmacological and supplementary treatments for ADHD. Treatment...... parts of cognition, mostly on the working memory or attention but with poor generalization of training on other cognitive functions and functional outcome. Children with ADHD have a variety of cognitive dysfunctions, and it is important that cognitive training target multiple cognitive functions...

  7. Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)

    DEFF Research Database (Denmark)

    Storebø, Ole Jakob; Ramstad, Erica; Krogh, Helle B;

    2015-01-01

    BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed and treated psychiatric disorders in childhood. Typically, children with ADHD find it difficult to pay attention, they are hyperactive and impulsive.Methylphenidate is the drug most often prescribed to...... treat children and adolescents with ADHD but, despite its widespread use, this is the first comprehensive systematic review of its benefits and harms. OBJECTIVES: To assess the beneficial and harmful effects of methylphenidate for children and adolescents with ADHD. SEARCH METHODS: In February 2015 we...... methylphenidate to request published and unpublished data. SELECTION CRITERIA: We included all randomised controlled trials (RCTs) comparing methylphenidate versus placebo or no intervention in children and adolescents aged 18 years and younger with a diagnosis of ADHD. At least 75% of participants needed to have...

  8. Who says this is a modern disorder? The early history of attention deficit hyperactivity disorder.

    Science.gov (United States)

    Martinez-Badía, Jose; Martinez-Raga, Jose

    2015-12-22

    Attention-deficit hyperactivity disorder (ADHD) is a complex, heterogeneous and multifactorial neurodevelopmental disorder characterized by persistent symptoms of inattention, hyperactivity and impulsivity. Although the first clinical description of a constellation of symptoms highly resembling to what currently could be diagnosed as ADHD is generally attributed to George F Still in 1902, there are scattered but significant published historical medical, scientific and non-scientific reports, much prior to Still's lectures, of what is currently conceptualized as ADHD. The present report aimed at exploring the early history of ADHD, prior to the 20(th) century in the medical literature and in other historical sources, to provide clinicians, researchers and other professionals with a better understanding of the roots and current conceptualization of this disorder. It is possible to find clues and highly suggestive descriptions of individuals presenting symptoms resembling what is currently defined as ADHD in the literature, in paintings or in the Bible. However, the earliest medical reports of individuals with abnormal degrees of inattention, distractibility and overactivity date from the last quarter of the 18(th) century, included in two of the first textbooks specifically on the subject of mental diseases, published by the German Melchior Adam Weikard and the Scottish Sir Alexander Crichton. During the 19(th) century some eminent physicians from Germany, France or Great Britain, such as Charles West, Thomas C Albutt, Thomas S Clouston, William W, Ireland, John Haslam, Heinrich Neumann, or Désiré-Magloire Bourneville, among others provided clinical depictions of patients that most likely presently would be diagnosed as having ADHD. Whilst some of the children described by Still and his predecessors may have suffered from a variety of neurological and psychiatric disorders, many of these patients showed clear symptoms of ADHD and may present with comorbid disorders

  9. Differential motor alterations in children with three types of attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Adrián Poblano

    2014-11-01

    Full Text Available Objective To determine frequency of motor alterations in children with attention deficit hyperactivity disorder (ADHD. Method We evaluated 19 children aged 7-12 years with ADHD classified in three sub-types: Combined (ADHD-C, with Inattention (ADHD-I, and with Hyperactivity (ADHD-H. Controls were age- and gender matched healthy children. We utilized Bruininks-Oseretsky Test of Motor Proficiency (BOTMP for measuring motor skills. Results We observed differences between children with ADHD and controls in BOTMP general score and in static coordination, dynamic general- and hand- coordination, and in synkinetic movements. We also found differences in dynamic hand coordination between controls and children with ADHD-C; in dynamic general coordination between controls and children with ADHD-H; and in frequency of synkinetic movements between controls and children with ADHD-H. Conclusion Children with ADHD with a major degree of hyperactivity showed greater frequency of motor alterations.

  10. Predictive coding in autism spectrum disorder and attention deficit hyperactivity disorder.

    Science.gov (United States)

    Gonzalez-Gadea, Maria Luz; Chennu, Srivas; Bekinschtein, Tristan A; Rattazzi, Alexia; Beraudi, Ana; Tripicchio, Paula; Moyano, Beatriz; Soffita, Yamila; Steinberg, Laura; Adolfi, Federico; Sigman, Mariano; Marino, Julian; Manes, Facundo; Ibanez, Agustin

    2015-11-01

    Predictive coding has been proposed as a framework to understand neural processes in neuropsychiatric disorders. We used this approach to describe mechanisms responsible for attentional abnormalities in autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). We monitored brain dynamics of 59 children (8-15 yr old) who had ASD or ADHD or who were control participants via high-density electroencephalography. We performed analysis at the scalp and source-space levels while participants listened to standard and deviant tone sequences. Through task instructions, we manipulated top-down expectation by presenting expected and unexpected deviant sequences. Children with ASD showed reduced superior frontal cortex (FC) responses to unexpected events but increased dorsolateral prefrontal cortex (PFC) activation to expected events. In contrast, children with ADHD exhibited reduced cortical responses in superior FC to expected events but strong PFC activation to unexpected events. Moreover, neural abnormalities were associated with specific control mechanisms, namely, inhibitory control in ASD and set-shifting in ADHD. Based on the predictive coding account, top-down expectation abnormalities could be attributed to a disproportionate reliance (precision) allocated to prior beliefs in ASD and to sensory input in ADHD. PMID:26311184

  11. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: A double blind and randomized trial [ISRCTN64132371

    OpenAIRE

    Mohammadi Mohammad-Reza; Akhondzadeh Shahin; Khademi Mojgan

    2004-01-01

    Abstract Background Attention-deficit hyperactivity disorder is an early-onset, clinically heterogenous disorder of inattention, hyperactivity, and impulsiveness. The diagnosis and treatment of attention-deficit hyperactivity disorder continues to raise controversy, and, there is also an increase in treatment options. In this 6-week double blind, placebo controlled-trial, we assessed the effects of zinc plus methylphenidate in the treatment of children with attention deficit hyperactivity dis...

  12. Disorder-specific and shared neurophysiological impairments of attention and inhibition in women with attention-deficit/hyperactivity disorder and women with bipolar disorder

    OpenAIRE

    Michelini, G.; Kitsune, G.L; Hosang, G M; Asherson, P.; Mcloughlin, G.; Kuntsi, J.

    2015-01-01

    BACKGROUND: In adults, attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) have certain overlapping symptoms, which can lead to uncertainty regarding the boundaries of the two disorders. Despite evidence of cognitive impairments in both disorders separately, such as in attentional and inhibitory processes, data on direct comparisons across ADHD and BD on cognitive-neurophysiological measures are as yet limited. Method We directly compared cognitive performance and event-...

  13. The Prevalence of DSM-IV Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review

    OpenAIRE

    Willcutt, Erik G.

    2012-01-01

    This article describes a comprehensive meta-analysis that was conducted to estimate the prevalence of attention-deficit/hyperactivity disorder (ADHD), as defined by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV). A systematic literature review identified 86 studies of children and adolescents (N = 163,688 individuals) and 11 studies of adults (N = 14,112 individuals) that met inclusion criteria for the meta-analysis, more than half of which were published a...

  14. [Methylphenidate in the treatment of children with attention-deficit hyperactivity disorder: monitoring in biological matrices].

    Science.gov (United States)

    Papaseit, E; García-Algar, O; Simó, S; Pichini, S; Farré, M

    2013-02-01

    Attention-deficit hyperactivity disorder (ADHD) has emerged in the last few years as the most commonly diagnosed and treated psychiatric disorder in the paediatric population. In 1980's, methylphenidate (MFD) a psychomotor stimulant drug, was approved in Spain for the symptomatic therapy of ADHD. Since then, MFD has become one of the most extensively prescribed and studied treatment for ADHD both in children and adults. In this paper, the main pharmacological issues of MFD are reviewed, focusing on its pharmacokinetics in conventional (blood and urine) and non-conventional (hair, oral fluid and sweat) biological matrices, its pharmaceutical preparations, therapeutic levels and side effects. PMID:23063334

  15. Attention deficit hyperactivity disorder and disordered eating behaviors: links, risks, and challenges faced

    Science.gov (United States)

    Ptacek, Radek; Stefano, George B; Weissenberger, Simon; Akotia, Devang; Raboch, Jiri; Papezova, Hana; Domkarova, Lucie; Stepankova, Tereza; Goetz, Michal

    2016-01-01

    Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists in adulthood. It is defined by inattention and/or hyperactivity–impulsivity. ADHD is associated with many comorbidities, including eating disorders (EDs). In the last decade, studies have reported that ADHD is linked with binge EDs, bulimia nervosa, and anorexia nervosa. Many postulates have been proposed to explain the association: 1) impulsive behavior in ADHD patients leads to disordered eating behavior; 2) other psychologic comorbidities present in ADHD patients account for eating behavior; 3) poor eating habits and resulting nutritional deficiencies contribute to ADHD symptoms; and 4) other risk factors common to both ADHD and EDs contribute to the coincidence of both diseases. Additionally, sex differences become a significant issue in the discussion of EDs and ADHD because of the higher incidence of bulimia nervosa and anorexia nervosa in females and the ability of females to mask the symptoms of ADHD. Interestingly, both EDs and ADHD rely on a common neural substrate, namely, dopaminergic signaling. Dopaminergic signaling is critical for motor activity and emotion, the latter enabling the former into a combined motivated movement like eating. This linkage aids in explaining the many comorbidities associated with ADHD. The interconnection of ADHD and EDs is discussed from both a historical perspective and the one based on the revealing nature of its comorbidities. PMID:27042070

  16. Adult attention deficit hyperactivity disorder and violence in the population of England: does comorbidity matter?

    Directory of Open Access Journals (Sweden)

    Rafael A González

    Full Text Available BACKGROUND: It is unclear whether the association between Attention Deficit/Hyperactivity Disorder (ADHD and violence is explained by ADHD symptoms or co-existing psychopathology. We investigated associations of ADHD and its symptom domains of hyperactivity and inattention, among individuals reporting violence in the UK population. METHODS: We report data from the Adult Psychiatric Morbidity Survey (2007, a representative sample of the household population of England. A randomly selected sample of 7,369 completed the Adult Self-Report Scale for ADHD and the self-reported violence module, including repetition, injury, minor violence, victims and location of incidents. All models were weighted to account for non-response and carefully adjusted for demography and clinical predictors of violence: antisocial personality, substance misuse and anxiety disorders. RESULTS: ADHD was moderately associated with violence after adjustments (OR 1.75, p = .01. Hyperactivity, but not inattention was associated with several indicators of violence in the domestic context (OR 1.16, p = .03. Mild and moderate ADHD symptoms were significantly associated with violence repetition, but not severe ADHD where the association was explained by co-existing disorders. Stratified analyses further indicated that most violence reports are associated with co-occurring psychopathology. CONCLUSIONS: The direct effect of ADHD on violence is only moderate at the population level, driven by hyperactivity, and involving intimate partners and close persons. Because violence associated with severe ADHD is explained by co-existing psychopathology, interventions should primarily target co-existing disorders.

  17. Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes.

    Science.gov (United States)

    Willcutt, Erik G; Nigg, Joel T; Pennington, Bruce F; Solanto, Mary V; Rohde, Luis A; Tannock, Rosemary; Loo, Sandra K; Carlson, Caryn L; McBurnett, Keith; Lahey, Benjamin B

    2012-11-01

    Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria for attention deficit/hyperactivity disorder (ADHD) specify two dimensions of inattention and hyperactivity-impulsivity symptoms that are used to define three nominal subtypes: predominantly hyperactive-impulsive type (ADHD-H), predominantly inattentive type (ADHD-I), and combined type (ADHD-C). To aid decision making for DSM-5 and other future diagnostic systems, a comprehensive literature review and meta-analysis of 546 studies was completed to evaluate the validity of the DSM-IV model of ADHD. Results indicated that DSM-IV criteria identify individuals with significant and persistent impairment in social, academic, occupational, and adaptive functioning when intelligence, demographic factors, and concurrent psychopathology are controlled. Available data overwhelmingly support the concurrent, predictive, and discriminant validity of the distinction between inattention and hyperactivity-impulsivity symptoms, and indicate that nearly all differences among the nominal subtypes are consistent with the relative levels of inattention and hyperactivity-impulsivity symptoms that define the subtypes. In contrast, the DSM-IV subtype model is compromised by weak evidence for the validity of ADHD-H after first grade, minimal support for the distinction between ADHD-I and ADHD-C in studies of etiological influences, academic and cognitive functioning, and treatment response, and the marked longitudinal instability of all three subtypes. Overall, we conclude that the DSM-IV ADHD subtypes provide a convenient clinical shorthand to describe the functional and behavioral correlates of current levels of inattention and hyperactivity-impulsivity symptoms, but do not identify discrete subgroups with sufficient long-term stability to justify the classification of distinct forms of the disorder. Empirical support is stronger for an alternative model that would replace the subtypes with dimensional

  18. Review of the Literature Regarding the Efficacy of Neurofeedback in the Treatment of Attention Deficit Hyperactivity Disorder.

    Science.gov (United States)

    Lingenfelter, Jennifer E.

    This document presents a review of the most recent literature regarding the efficacy of electroencephalographic biofeedback, more commonly known as neurofeedback, in the treatment of attention deficit hyperactivity disorder (ADHD). The studies reviewed indicated that neurofeedback can be a successful component of treating attentional deficits and…

  19. Neurofibromatosis type 1 and attention deficit hyperactivity disorder: a case study and literature review

    Directory of Open Access Journals (Sweden)

    Miguel CS

    2015-03-01

    Full Text Available Carmen Sílvia Miguel, Tiffany M Chaim-Avancini, Maria Aparecida Silva, Mario Rodrigues LouzãAdult Attention Deficit Hyperactivity Disorder Program (PRODATH, Institute of Psychiatry, University of São Paulo, São Paulo, BrazilBackground: The cognitive profile of children with neurofibromatosis type 1 (NF1 and attention deficit hyperactivity disorder (ADHD has been well characterized, but few studies have evaluated the cognitive abilities of adults with NF1 and ADHD.Objectives: We investigated 1 the cognitive profile of an adult patient with NF1 and inattention problems, 2 changes in his cognition after 14 months of follow-up, and 3 whether the patient exhibited comorbid NF1 and ADHD or secondary ADHD-like symptoms.Methods: We administered neuropsychological tests of executive function, attention, verbal and visual memory, visuospatial function, and language during two evaluations separated by 14 months.Results: We found no changes in sustained attention, language, or verbal memory. Visual memory, verbal learning, selective attention inhibitory control, and problem solving declined over time, whereas visual search, psychomotor speed, visuospatial function, and mental flexibility improved.Conclusion: Our patient exhibited a cognitive profile characteristic of both NF1 and ADHD, leading to the hypothesis that the patient had comorbid ADHD instead of secondary ADHD-like symptoms. More studies are necessary to characterize the cognition of patients with NF1 and ADHD.Keywords: ADHD, executive function, NF1, low-grade pontine glioma, cognition

  20. Early Development of Comorbidity Between Symptoms of Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder

    Science.gov (United States)

    Harvey, Elizabeth A.; Breaux, Rosanna P.; Lugo-Candelas, Claudia I.

    2015-01-01

    Attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are among the most common childhood disorders and frequently co-occur. The present study sought to advance our understanding of how comorbidity between ADHD and ODD develops during the preschool years by testing a cross-lagged model that integrates two prominent models: the developmental precursor model and the correlated risk factors model. Participants were 199 children (107 boys) who took part in a longitudinal study of preschoolers with behavior problems. Parent reports of ADHD and ODD symptoms were collected annually from ages 3 to 6 and a family history interview was administered at age 3. In support of the developmental precursors model, ADHD symptoms predicted later argumentative/defiant symptoms. In support of the correlated risk factors model, family histories of ADHD and ODD/CD symptoms were correlated risk factors that uniquely predicted ADHD and anger/irritable symptoms in children. Results suggest that the correlated risk factors model may best explain the development of comorbidity between symptoms of ADHD and anger/irritability, whereas the developmental precursors model may better explain the development of comorbidity between symptoms of ADHD and argumentative/defiance. PMID:26854502