WorldWideScience

Sample records for atrieseptumdefekt hos voksne

  1. Forebyggelse af dyb venetrombose (DVT) i underekstremiteter hos voksne hospitalsindlagte patienter gennem mobilisering

    DEFF Research Database (Denmark)

    Jensen, Jonna Gintberg

    2011-01-01

    Titel: Forebyggelse af dyb ventrombose (DVT) i underekstremiteterne hos voksne hospitalsindlagte patienter gennem mobilisering. Konklusion eller hovedbudskabet: Der foreligger ikke evidens for hvor meget, hvor længe og hvordan indlagte patienter skal mobiliseres for at forebygge dyb venetrombose(DVT......) Sideløbende med kursus i udvikling af kliniske retningslinjer har kursus deltagere og baggrundsgruppe - haft det mål, at undersøge hvilken evidens der foreligger i forhold til mobilisering af indlagte voksne patienter. Vores udgangspunkt tog afsæt i daglig klinisk praksis og en viden om, at DVT rammer en stor...... del af de indlagte patienter. Venøs trombose (VT) er den tredje største kardiovaskulære sygdom efter akut myokardieinfarkt og apopleksi (1). I et større norsk studie fandt man en incidensrate af VT på 1.43 per 1.000 personår, hvoraf dyb venetrombose (DVT) udgjorde 0.93 per 1.000 personår af de...

  2. Kawasakis syndrom hos voksne

    DEFF Research Database (Denmark)

    Roed, Casper; Skinhøj, Peter

    2009-01-01

    Kawasaki syndrome (KS), which is febrile systemic vasculitis complicated by coronary aneurysms, was initially described in children, but an increasing number of case-reports address adult-KS. The disease seems to be infectious of origin, but the causative agent has not been established. The debut...

  3. Staphylococcal scalded skin syndrome hos voksne

    DEFF Research Database (Denmark)

    Mikkelsen, Carsten Sauer; Mikkelsen, Dorthe Bisgaard; Jensen, Thøger Gorm

    2010-01-01

    We describe a case of adult staphylococcal scalded skin syndrome (SSSS) in a 91-year-old woman. The patient had a Staphylococcus aureus infection in her right ear with redness and yellow secretion. A few days later she developed Nikolsky sign-positive tender enlarged flaccid bullae involving most...

  4. Periacetabulaer osteotomi og hoftedysplasi hos yngre voksne

    DEFF Research Database (Denmark)

    Troelsen, Anders; Søballe, Kjeld

    2009-01-01

    The periacetabular osteotomy is recognized as the surgical treatment of choice in young adults with symptomatic hip dysplasia. The procedure is performed to delay or prevent the development of osteoarthritis. The procedure has the ability to improve function and preserve hip joints in > 80% of ca...

  5. Spilleregler i musikterapi med voksne

    DEFF Research Database (Denmark)

    Holck, Ulla

    2005-01-01

    Artiklen gennemgår udvalgt faglitteratur, der på et overordnet plan beskriver typer af spilleregler i musikterapi med (fortrinsvis) voksne klientgrupper. Udgangspunktet er Priestleys anvendelse af begrebet, og hendes inddeling af spilleregler i forhold til forskellige teknikker gennemgås, efterfu...

  6. Best Practice i matematikundervisning for voksne

    DEFF Research Database (Denmark)

    Johansen, Lene Østergaard

    2005-01-01

    I min ph.d.-afhandling beskæftiger jeg mig med begrundelsesproblemet og særligt med spørgsmålet - hvorfor skal voksne uden grundlæggende færdigheder i matematik tilbydes undervisning i matematik? Jeg har taget udgangspunkt i udviklingen af den nye uddannelse for voksne - Forberedende Voksenunderv...

  7. ADHD - et voksende problem for voksne

    DEFF Research Database (Denmark)

    Jørgensen, Anthon Sand

    2013-01-01

    Mindst 1000.000 voksne opfylder ADHD-diagnosekriterierne, og en stor del af disse kan risikere at ende i kriminalitet, misbrug eller stå uden job......Mindst 1000.000 voksne opfylder ADHD-diagnosekriterierne, og en stor del af disse kan risikere at ende i kriminalitet, misbrug eller stå uden job...

  8. Cochleaimplantationer hos voksne. Resultater og betydning for kommunikation og livskvalitet

    DEFF Research Database (Denmark)

    Faber, C E; Grøntved, A M

    2000-01-01

    The aim of this study was to assess the benefits and complications from cochlear implantation and to evaluate the average implant usage per day. Ten profoundly deaf adults were implanted during the period April 1994 to September 1997. The patients answered questionnaires one year or more after...... receiving their cochlear implants. The average implant usage per day was 16 hours. The patients would again opt for a cochlear implant and would recommend a cochlear implant for a deaf friend. A paired comparison showed that the implants led to statistically significant improvement in a number of factors...

  9. Behandling af mani hos voksne (Treatment of mania in adults)

    DEFF Research Database (Denmark)

    Licht, Rasmus Wentzer; Straszek, Sune Puggaard Vogt

    2014-01-01

    Around 1% of the population will experience at least one episode of mania. Mania has negative social consequences, may lead to cognitive impairment and may even be lethal. Therefore, prompt and efficient medical action needs to be taken, not only addressing the acute symptoms but also the high ri...... of recurrence. Many well-documented antimanic drugs are at hand, and the database has been carefully outlined in recent guidelines, also addressing factors of importance in choosing among the options. The real challenge is dealing with non-response, where the database is extremely poor....

  10. Diagnostik og behandling af næsefraktur hos voksne

    DEFF Research Database (Denmark)

    Sjöstedt, Sannia; Larsen, Christian Grønhøj; Bilde, Anders;

    2016-01-01

    The risk of complications warrants treatment of most dislocated nasal fractures. Other injuries including other facial fractures and septal haematoma must be treated if present at the initial presentation. The usual treatment for a simple nasal fracture is closed reduction in local anaesthesia...... after five to seven days. Complicated cases require open reduction in general anaesthesia. Later revision of the deviated nose may become necessary in patients suffering from complications such as persistent nasal stenosis and/or deformity....

  11. Udredning af knude på halsen hos voksne

    DEFF Research Database (Denmark)

    Larsen, Christian Grønhøj; Channir, Hani Ibrahim; Kiss, Katalin

    2015-01-01

    Doctors are frequently presented to patients with a neck mass, and the condition might cause diagnostic challenges. In younger adults, a neck mass can typically be explained by congenital, inflammatory or infectious causes. The highest probability of neoplasms is found in patients above 40 years ...

  12. Best Practice i matematikundervisning for voksne

    DEFF Research Database (Denmark)

    Johansen, Lene Østergaard

    2005-01-01

    Voksenundervisning (FVU) og særligt i faget FVU-matematik. Jeg har i mine analyser valgt at skelne mellem tre forskellige Diskurser: Politikernes Diskurs, Forskernes Diskurs og matematiklærernes Diskurs. Et af fokuspunkterne i mine analyser er, hvorledes Best Practice italesættes i de tre Diskurser, eller med andre...... ord - hvad er god undervisning for voksne ifølge politikerne, ifølge forskerne og ifølge matematiklærerne? I artiklen præsenterer og diskuterer jeg de tre Diskursers forskellige opfattelser af Best Practice i matematikundervisning for voksne....

  13. Voksnes regnefærdigheder/numeralitet - hvordan testes det?

    DEFF Research Database (Denmark)

    Johansen, Lene Østergaard

    2004-01-01

    Vi befinder os i en evalueringsbølge. Børn og voksnes viden og færdigheder bliver i disse år evalueret gang på gang, og resultaterne bliver sammenlignet og diskuteret nationalt og internationalt. Når et lands befolkning klarer sig dårligt i forhold til andre landes befolkninger, bliver resultater...

  14. Deltagerorienteret undervisning hos Naviair

    DEFF Research Database (Denmark)

    Allermand, Geert; Rosenkvist, Gert; Leve, Ulrik;

    2011-01-01

    En artikel om et udviklingsprojekt hos flysikringstjenesten Naviair i forbindelse med deres implementering af et simulatorpædagogisk koncept.......En artikel om et udviklingsprojekt hos flysikringstjenesten Naviair i forbindelse med deres implementering af et simulatorpædagogisk koncept....

  15. Strubelammelse hos hund

    DEFF Research Database (Denmark)

    Miles, James; Eriksen, Thomas

    2007-01-01

    og hoste. Strubelammelse er enten medfødt eller erhvervet. Den medfødte form udgør 20-30 procent af patienter, hvor symptomerne debuterer hos unge dyr med kraftig ophobning i racer som Bouvier de Flandre, Siberian husky, Dalmatiner og Bull terrier. Den erhvervede lammelse er den hyppigste form og ses...

  16. Hos de uvidende

    DEFF Research Database (Denmark)

    Bertelsen, Pernille Scholdan; Dahms, Mona-Lisa

    2004-01-01

    I artiklen "Hos de ?uvidende? ? om tavs viden og teknologisk forandring i Tanzania? undersøges tavs viden som ressource i de teknologiske forandrings - processer, som finder sted i Tanzanias landdistrikter. Med en teoretisk ramme for viden, teknologisk viden og innovation, arbejdes der i artiklen...

  17. Strubelammelse hos hund

    DEFF Research Database (Denmark)

    Miles, James; Eriksen, Thomas

    2007-01-01

    primært hos ældre eller gamle hunde af store racer. Dysfunktionen skyldes lammelse af den indre strubemuskulatur (m. cricoarytenoideus dorsalis, lateralis og thyroarytenoideus), der innerveres af n. laryngeus recurrens. N. laryngeus cranialis, der innerverer m. cricothyreoideus - hvilken fungerer som...

  18. Ensamhetsmotivet hos Ivar Arosenius

    OpenAIRE

    Franzén, Niclas

    2010-01-01

    Uppsatsen behandlar ensamhetsmotivet hos konstnären Ivar Arosenius. Ensamhetsbilderna delas in i olika kategorier efter motiv och stämningsläge. Bilderna analyseras sedan med fokus på symbolistiska tendenser, återkommande teman och influenser från andra konstnärer. This paper deals with the solitude motif of the artist Ivar Arosenius. His solitude pictures are divided into different categories according to subject and sentiment. The images are then analyzed with a focus on symbolistic ten...

  19. Phaedra hos Seneca og Racine

    DEFF Research Database (Denmark)

    Bloch, David Kristian

    2007-01-01

    Denne artikel omhandler Phaedra-skikkelsen, som den fremstilles hos hhv. Seneca og Racine i deres respektive tragedier. Begge tragedier, men især Racines, diskuteres og analyseres indgående. Udgivelsesdato: 1. oktober......Denne artikel omhandler Phaedra-skikkelsen, som den fremstilles hos hhv. Seneca og Racine i deres respektive tragedier. Begge tragedier, men især Racines, diskuteres og analyseres indgående. Udgivelsesdato: 1. oktober...

  20. Postural balanse og vestibulær funksjon hos hørselshemmede voksne - en kasus-kontroll studie

    OpenAIRE

    2014-01-01

    Background: There are indications that some hearing-impaired individuals have decreased postural balance compared with normal hearing individuals. This balance impairment can be due to damage of the vestibular system.The aim of the study was to: 1) compare the postural balance between a group of hearing-impaired and a group of normal hearing adults, in standing position and while walking; 2) Examine the vestibular function in the hearing-impaired individuals; 3) Evaluate which ...

  1. Måltidsvaner for voksne med kort uddannelse 2005-2008

    DEFF Research Database (Denmark)

    Christensen, Lene Møller; Kørup, Karsten; Trolle, Ellen

    fredag aftensmad til søndag sen aften) er af en mindre god ernæringsmæssig kvalitet end kosten i hverdagene. På nær alkohol er forskellene dog små. En indsats til forbedring af de kortuddannede voksnes kostvaner bør derfor både fokusere på hverdagenes og weekendens måltider. Den største andel af...

  2. Blødningsforstyrrelser hos kvinder

    DEFF Research Database (Denmark)

    Astrup, Karen

    1994-01-01

    Efteruddannelsesartikel for praktiserende læger om undersøgelse og behandling af blødningsforstyrrelser hos kvinder i almen praksis. Udgivelsesdato: 1994......Efteruddannelsesartikel for praktiserende læger om undersøgelse og behandling af blødningsforstyrrelser hos kvinder i almen praksis. Udgivelsesdato: 1994...

  3. Når eplet faller langt fra stammen ... : en studie av voksne utenlandsadopterte i Norge

    OpenAIRE

    Rasmussen, Mariann

    2000-01-01

    Utenlandsadopsjon er et tema som stort sett har blitt drøftet og undersøkt i forhold til foreldre og barn. Ettersom den første generasjonen av adopterte nå har blitt voksne er det verdifull kunnskap å hente ut fra deres egne erfaringer og tanker rundt det å være adoptert. Det viser seg at deres formidling av erfaringer kan være med på å sette utenlandsadopsjon i et nytt perspektiv og rette fokus mot problemstillinger som ikke har blitt gitt så mye oppmerksomhet tidligere. Jeg har vært i ...

  4. Organisationsudvikling og socialpædagogisk praksis i bo- og dagtilbud for voksne udviklingshæmmede

    DEFF Research Database (Denmark)

    Kofod, Kasper; Jensen, Niels Rosendal

    Bogen er en rapport over et forsknings- og udviklingsprojekt for Organisationen for Voksne Udviklingshæmmede i Ballerup Kommune, som er forløbet fra marfts 2008 til februar 2009. Rapporten er en forløbsrapport, som gør rede for processen i projektet og for de første analyser af de observerede...

  5. Kortlægning af it-kompetenceudviklingsmuligheder i det ikke-formelle it-undervisningssystem for voksne i Danmark

    DEFF Research Database (Denmark)

    Rattleff, Pernille; Duus Henriksen, Thomas

    Formålet med denne kortlægning er ”at tilvejebringe et retvisende og fyldestgørende overblik over de eksisterende muligheder for it-kompetenceudvikling i det ikke-formelle it-undervisningssystem for voksne i Danmark” (jf. udbudsmaterialet, p. 51). Kortlægningen skal klarlægge, i hvilken udstrækni...

  6. Identifiable Data Files - Health Outcomes Survey (HOS)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medicare Health Outcomes Survey (HOS) identifiable data files are comprised of the entire national sample for a given 2-year cohort (including both respondents...

  7. BLIND ADAPTIVE XPIC BASED ON HOS

    Institute of Scientific and Technical Information of China (English)

    Fu Haiyang; Yang Longxiang; Peng Jianglong

    2001-01-01

    This paper presents a new blind XPIC and a new adaptive blind deconvolutional algorithm based on HOS processing, which separates and equalizes the signals in real time. The simulation results demonstrate that the performance of the proposed adaptive blind algorithm,compared with the conventional algorithms, is outstanding with the feature of feasibility, stability and fast convergence rate.

  8. Idrætsskader hos motionisten III

    DEFF Research Database (Denmark)

    Fredberg, Ulrich; Honoré, Niels; Charles, Morten

    2015-01-01

    Overbelastningsskader er hyppige – også hos børn. Ofte holdes skaden ved lige på grund af en manglende forståelse for det uhensigtsmæssige i det savtakkede genoptræningsforløb, hvor man genoptager belastningen på maksimalt niveau, så snart smerterne er svundet. Behandlingen består ofte i at forkl...

  9. Eosinofil keratitis hos en dansk hest

    DEFF Research Database (Denmark)

    Olsen, Emil; Henriksen, Michala de Linde; Andersen, Pia Haubro

    2009-01-01

    Eosinofil keratitis (EK) er en relativt sjælden øjenlidelse hos hest, som især ses i tempererede områder. Klinisk er lidelsen karakteriseret ved én eller multiple corneaulcerationer dækket med hvidt eller gelatinøst proliferativt subepithelialt plaque. Denne casereport, som omhandler en 20-årig p...

  10. Måling af stress hos mink

    DEFF Research Database (Denmark)

    Malmkvist, Jens

    2010-01-01

    temadagen præsenteres nye resultater og metoder til at vurdere stress hos mink. I en metode måles koncentrationen af nedbrydningsprodukter af hormonet cortisol i gødning fra mink. Der er en række fordele ved denne metode, frem for blodprøvetagning. Forsøg viste, at hovedparten af cortisol udskilles i fæces...... (83 %) frem for i urin (17 %), samt at omsætningen af radioaktivt mærket cortisol ikke er forskellig mellem mink med hhv. lav og høj forekomst af stereotypi. Denne viden kan bruges til bedre at forstå koblingen f.eks. unormal adfærd og stress hos mink.......Sammendrag Stress indgår som et element ved vurdering af dyrevelfærd. Endvidere kan stress mål anvendes i undersøgelser, hvor forskellige typer af avl, burmiljø og pasning af mink sammenlignes. Men hvad er stress egentlig og hvordan måles det? Er unormal adfærd koblet til stress hos mink? På...

  11. Demodex og andre ektoparasitter hos danske katte

    DEFF Research Database (Denmark)

    Memborg Jensen, Mia C.; Boysen, Lene; Thamsborg, Stig Milan

    2015-01-01

    Raske katte og katte med hudforandringer blev undersøgt for at belyse forekomst og betydning af Demodex. En tredje gruppe af aflivede vild- og tamkatte blev desuden undersøgt for forekomst af andre ektoparasitter. Forskellige diagnostiske teknikker blev anvendt og evalueret i undersøgelsen. I alt...... indgik 176 katte, som blev undersøgt ved hårpluk, hudskrab, tapetest, flotation affæcesprøve, øreskrab samt kæmning af pelsen. Demodex spp. blev fundet hos tre katte, og hos én af disse blev iagttaget klinisk demodicose. Demodex spp. blev ikke påvist i gruppen af raske katte. Den samlede forekomst af...... ektoparasitter hos de aflivede vild-og tamkatte var 57%. Følgende ektoparasitter blev påvist: Ctenocephalidesfelis felis, Otodectes cynotis, Ixodes spp., Felicola subrostrata,Cheyletiella blakei og Demodex spp.. Alle de anvendte diagnostiske teknikker var effektive til påvisningen af forskellige ektoparasitter...

  12. Aggressiv periodontitt hos barn og unge

    OpenAIRE

    Pham, Hong Tram Thi

    2006-01-01

    1999 International Classification Workshop (1) innførte begrepet aggressiv periodontitt (AgP) i det nye klassifikasjonssystemet for periodontitt. AgP inkluderer gruppene tidligere klassifisert som: Prepubertal periodontitt Juvenil periodontitt Raskt progredierende periodontitt Vår oppgave omhandler AgP hos barn og unge. Ifølge WHO’s definisjon, er barn personer mellom 0-18 år. Vi har derfor tatt for oss de 2 første av de 3 gruppene under definisjonen AgP, tidligere kalt...

  13. Adaptive filtering using Higher Order Statistics (HOS

    Directory of Open Access Journals (Sweden)

    Abdelghani Manseur

    2012-03-01

    Full Text Available The performed job, in this study, consists in studying adaptive filters and higher order statistics (HOS to ameliorate their performances, by extension of linear case to non linear filters via Volterra series. This study is, principally, axed on: „ Choice of the adaptation step and convergence conditions. „ Convergence rate. „ Adaptive variation of the convergence factor, according to the input signal. The obtained results, with real signals, have shown computationally efficient and numerically stable algorithms for adaptive nonlinear filtering while keeping relatively simple computational complexity.

  14. Functional characterization of Candida albicans Hos2 histone deacetylase.

    Science.gov (United States)

    Karthikeyan, G; Paul-Satyaseela, Maneesh; Dhatchana Moorthy, Nachiappan; Gopalaswamy, Radha; Narayanan, Shridhar

    2013-01-01

    Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush) infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals. Azoles have been very effective anti-fungal agents and the mainstay in treating opportunistic mold and yeast infections. Azole resistant strains have emerged compromising the utility of this class of drugs. It has been shown that azole resistance can be reversed by the co-administration of a histone deacetylase (HDAC) inhibitor, suggesting that resistance is mediated by epigenetic mechanisms possibly involving Hos2, a fungal deacetylase. We report here the cloning and functional characterization of  HOS2 (High Osmolarity  Sensitive) , a gene coding for fungal histone deacetylase from  C. albicans. Inhibition studies showed that Hos2 is susceptible to pan inhibitors such as trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA), but is not inhibited by class I inhibitors such as MS-275. This  in  vitro enzymatic assay, which is amenable to high throughput could be used for screening potent fungal Hos2 inhibitors that could be a potential anti-fungal adjuvant. Purified Hos2 protein consistently deacetylated tubulins, rather than histones from TSA-treated cells. Hos2 has been reported to be a putative NAD+ dependent histone deacetylase, a feature of sirtuins. We assayed for sirtuin activation with resveratrol and purified Hos2 protein and did not find any sirtuin activity.

  15. Musikterapi til reduktion af agitation hos personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Stige, Brynjulf

    2015-01-01

    Urolig adfærd hos demensramte på plejehjem kan defineres og måles med fagbegrebet agitation. Agitation har alvorlige konsekvenser for de berørte og kan føre til fald i livskvalitet og øget medicinering hos personer med svær demens, og kan ligeledes føre til udbrændthed hos omsorgsgivere. Agitation...... regarding the single individual. A relevant method in an integrated and holistic approach is professional music therapy combined with other staffs’ use of music in daily dementia care....

  16. Musikterapi til reduktion af agitation hos personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Stige, Brynjulf

    2015-01-01

    Urolig adfærd hos demensramte på plejehjem kan defineres og måles med fagbegrebet agitation. Agitation har alvorlige konsekvenser for de berørte og kan føre til fald i livskvalitet og øget medicinering hos personer med svær demens, og kan ligeledes føre til udbrændthed hos omsorgsgivere. Agitatio...... regarding the single individual. A relevant method in an integrated and holistic approach is professional music therapy combined with other staffs’ use of music in daily dementia care........ The concept agitation is used professionally to define and measure disturbing behaviours in people with severe dementia. The causes are multiple and include factors in the psychosocial environment, which suggests that treatment should be holistic and interdisciplinary and not limited to symptom management...

  17. Ivermektinfølsomhed hos danske Collies og Border Collies

    DEFF Research Database (Denmark)

    Treschow, Michaela E. C.; Fredholm, Merete

    2007-01-01

    Anvendelse af ivermektin i terapeutiske doser til hunde medfører i visse tilfælde neurologiske bivirkninger. Der er tale om en idiosynkrasi, der benævnes ivermektinfølsomhed, og som primært er beskrevet hos hyrdehunderacer, herunder især Collies......Anvendelse af ivermektin i terapeutiske doser til hunde medfører i visse tilfælde neurologiske bivirkninger. Der er tale om en idiosynkrasi, der benævnes ivermektinfølsomhed, og som primært er beskrevet hos hyrdehunderacer, herunder især Collies...

  18. Testning af alment ordforråd hos danske universitetsstuderende: et normeringsstudie

    DEFF Research Database (Denmark)

    Langhoff Sørensen, Louise; Ravn Claumarch, Ida Elise; Weed, Ethan

    2017-01-01

    Artiklen indeholder udviklingen og afprøvningen af en ordforrådstest designet specielt til universi- tetsstuderende. Testen er en elektronisk, revideret version af ’Hvilket billede passer til ordet’ udviklet med udgangspunkt i de billeder og ord, der bruges i Vejledende Læsetest for Voksne (VLV)....

  19. Hofte- og lyskesmerter hos yngre fysisk aktive personer

    DEFF Research Database (Denmark)

    Jacobsen, Julie Sandell; Hölmich, Per; Thorborg, Kristian;

    2015-01-01

    kirurgi – til hvem og hvornår Sonia Branci: Billeddiagnostik – Klinisk anvendelse af MR Julie Jacobsen: Billeddiagnostik – Klinisk anvendelse af ultralydsskanning Kristian Thorborg: Smerte og funktionsnedsættelse hos forskellige patientgrupper med hoftesmerter Form: Introduktion til temaet, oplæg og...

  20. Vitamin D fysiologi og forsyning hos malkekvæg

    DEFF Research Database (Denmark)

    Hymøller, Lone; Jensen, Søren Krogh

    2015-01-01

    Vitamin D, som tilhører gruppen af fedtopløselige vitaminer, har de seneste år været et af de mest omdiskuterede næringsstoffer i både dansk og udenlandsk presse. Dette skyldes, at vitamin D har vist sig at have indflydelse på mange forskellige fysiologiske processer i kroppen lige fra...... kalciumbalance og knoglestyrke til immunforsvarets funktion. Hos malkekvæg betyder dette, at vitamin D potentielt har stor indflydelse på bl.a. risikoen for kælvningsproblemer og mælkefeber hos køer samt dyrenes generelle holdbarhed og sundhed. Gennem de seneste 10 år har forskere på AU Foulum intenst studeret...... vitamin D-forsyningen og -fysiologien hos malkekvæg. Resultaterne af disse undersøgelser har vist, at sommersollys er en meget vigtig kilde til vitamin D hos malkekøer, og der er en lineært stigende effekt på køernes vitamin D-status i blodet, jo længere tid de dagligt opholder sig i sommersolen. Tilskud...

  1. Alkohol, medicin og narkotikaforekomst hos alvorligt tilskadekomne bilister

    DEFF Research Database (Denmark)

    Bernhoft, Inger Marie; Hels, Tove; Simonsen, Kirsten Wiese

    2012-01-01

    Abstrakt Denne artikel omhandler forekomsten af alkohol, narkotika og medicin hos danske bilister, som er blevet alvorligt skadet i færdselsuheld. Undersøgelsen er baseret på anonyme blodprøver fra 840 førere af person- og varebiler, der blev indbragt til hospitalerne i Odense, Kolding, Vejle, Vi...

  2. Optimeret brug af genomisk selektion hos Dansk Jersey

    DEFF Research Database (Denmark)

    Thomasen, Jørn Rind

    2013-01-01

    Anvendelse af genomisk information øger sikkerheden på avlsværdier for unge avlsdyr uden egne registreringer og kan derfor øge avlsfremgangen. Derfor er genomisk selektion allerede blevet en del af beslutningsgrundlaget i mange avlsprogrammer hos malkekvæg. Metoden har dog vist sig at være mere...

  3. Funktionelle lidelser hos børn og unge

    DEFF Research Database (Denmark)

    Dehlholm-Lambertsen, Gitte; Hulgaard, Ditte Roth

    2017-01-01

    RESUME: Funktionelle somatiske symptomer hos børn og unge er en hyppig kontaktårsag i almen praksis. Forældrenes – og barnets – sygdomsforståelse har stor betydning for udvikling og vedligeholdelse af funktionelle lidelser. Gentagne undersøgelser i sundhedsvæsenet og familiens fokusering på fysis...

  4. CRYSTAL-STRUCTURE DETERMINATION OF THE MISFIT LAYER COMPOUND (HOS)1.23NBS2

    NARCIS (Netherlands)

    WIEGERS, GA; MEETSMA, A; HAANGE, RJ; DEBOER, JL

    1992-01-01

    Single-crystal X-ray diffraction has shown that (HoS)1.23NbS2 is a misfit layer compound built of alternate double layers of HoS, approximately a {001} slice of NaCl-type HoS, and sandwiches of NbS2 with niobium in trigonal prisms of sulphur like niobium in 2H-NbS2. The unit cell dimensions of the H

  5. Sprog hos børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2010-01-01

    Spredningen i sproglige færdigheder hos børn med autisme er enorm. Dette forhold vanskeliggør forskning inden for området, og omvendt bevirker forskningen og de valg – og ikke mindst fravalg – som autismeforskere er nødt til at foretage, at gruppen af børn med autisme kommer til at fremstå mere...

  6. Voksne danskeres kostbevidsthed

    DEFF Research Database (Denmark)

    Osler, M; Rasmussen, N K; Brønnum-Hansen, Henrik

    1990-01-01

    in the suburbs of the capital and in the three largest Danish provincial towns. The efforts to achieve healthy dietary habits are, in addition, associated with non-smoking and moderate alcohol consumption. During the past five years, the proportion of Danes who try to alter dietary habits has increased...

  7. HOS AND GA BASED INTERFERENCE REJECTION IN DIRECT SEQUENCE SPREAD SPECTRUM COMMUNICATION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Gong Xiangyang; Hu Guangrui; Li Taijie

    2003-01-01

    A new Higher Order Statistics (HOS) and Genetic Algorithm (GA)-based interference rejection filter is introduced. Compared with the adaptive filters based on second-order statistics and gradient algorithm, the HOS and GA-based filter can reject the interference more efficiently, is independent of uncorrelated Gaussian noise, tends to converge to the optimum solution and is much less sensitive to the choice of the step size parameter. Computer simulations show that the method can reject narrowband interference efficiently.

  8. Hvilken evidens er der for medikamentel behandling af depression hos børn og unge?

    DEFF Research Database (Denmark)

    Thomsen, Per Hove; Sørensen, Merete Juul

    2007-01-01

    Depression hos børn og unge er relativt hyppigt forekommende og kan have svære konsekvenser. Den specifikke antidepressive behandling kan være psykoterapeutisk eller medikamentel. I artiklen gennemgås på baggrund af systematisk litteratursøgning den videnskabelige evidens for medikamentel...... behandling af depression hos børn og unge med hovedvægten lagt på de mest veldokumenterede medikamenter: selektive serotoningenoptagelseshæmmere....

  9. Dannelsen af en psykologisk og videnskabelig habitus hos psykologistuderende

    DEFF Research Database (Denmark)

    Feilberg, Casper

    2014-01-01

    fra Merleau-Ponty, Gadamer, Ricoeur, Bion og Habermas. I en fænomenologisk fortolkning af Bourdieus habitusbegreb, fremhæves vanen som central for at forstå en professions opbyggede beredskab til at agere hensigtsmæssigt og professionelt i forhold til faglige problemstillinger; denne habitus angår......Dannelsen af en psykologisk og videnskabelig habitus hos psykologistuderende, Casper Feilberg Afhandlingen er en empirisk undersøgelse af psykologistuderendes tilegnelse af træk ved en psykologisk og videnskabelig habitus ved psykologistudierne på Roskilde Universitet og Aalborg Universitet. Herved...... bidrager afhandlingen til den overordnede diskussion om, hvad målet med og kvalitet i en universitetsuddannelse skal forstås som. Som udgangspunkt for studiet af psykologistuderendes dannelsesprocesser indføres en analytisk distinktion mellem en psykologisk habitus (fænomen orienteret), og en videnskabelig...

  10. Eksponering, lungefunksjon og inflammasjonsmarkører hos asfaltarbeidere*

    Directory of Open Access Journals (Sweden)

    Britt Grethe Randem

    2010-01-01

    Full Text Available Bakgrunn: Vi undersøkte om vi kunne påvise endringer i lungefunksjon og inflammasjonsmarkører hos asfaltarbeidere over en asfaltsesong på 6 måneder. Samtidig ønsket vi å karakterisere eksponeringen ved moderne asfaltarbeid, spesielt eksponeringen for ultrafine partikler.Materiale og metode: Alle asfaltarbeidere og asfaltingeniører ansatt hos Norges største entreprenør for veibygging ble invitert til å delta i en studie av lungefunksjon og markører for inflammasjon i luftveiene. Undersøkelsene ble utført i forkant av asfaltsesongen. Like før sesongavslutning ble studiegruppen undersøkt på nytt. Studiegruppen bestod av 72 asfaltleggere, 32 asfaltblandeverksarbeidere og en kontrollgruppe med 19 asfaltingeniører. Eksponeringsundersøkelser ble gjennomført både på vei og i asfaltverk.Resultater: Ultrafine partikler (UFP målt ved asfaltutleggeren kom hovedsaklig fra asfaltleggingsaktiviteter og fra trafikkeksos. Nivået av UFP var sammenlignbart med nivået ved rushtidstrafikk i en stor by. 74% av de målte partiklene på stedet var ultrafine. Asfaltleggerne hadde en statistisk signifikant stigning i interleukin-6 over asfaltsesongen sammenlignet med verksarbeidere, og asfaltleggere hadde større økning i CC16 over sesongen enn verksarbeidere og ingeniører. Skyflere, en gruppe asfaltleggere, hadde et statistisk signifikant fall i FVK og FEV1 målt ved sesongslutt.Fortolkning: Varm asfalt kan generere høye konsentrasjoner av UFP. Eksponering hos asfaltleggere kan bidra til akselerert reduksjon i lungefunksjon og økning i betennelsesmarkører som tegn på inflammasjon. Randem BG, Ulvestad B. Exposure, lung function and inflammation markers in asphalt workers. Nor J Epidemiol 2009; 19 (2: 229-234. ENGLISH SUMMARYBackground: Asphalt workers are exposed to aerosol/particles from the hot asphalt mix when paving. We investigated possible changes in lung function and markers of inflammation in the workers across a summer paving

  11. Forbedret diagnostik af osteomyelitis hos børn?

    DEFF Research Database (Denmark)

    Afzelius, Pia; Alstrup, Aage Kristian Olsen; Schønheyder, Henrik Carl;

    Osteomyelitis er en alvorlig sygdom. Tidlig diagnose og påbegyndelse af behandlingen er vigtigt for at forhindre sygdomsudviklingen og for at reducere potentielt alvorlige komplikationer. Konventionel røntgenundersøgelse udført tidligt i forløbet kan ikke udelukke akut osteomyelitis. MRI......, knogleskintigrafi og CT er centrale billeddiagnostiske metoder til diagnostik af akut osteomyelitis hos børn. MRI betragtes ofte som værende den bedste billeddannende metode, men er ikke altid tilgængelig og kræver anæstesi af små børn. Knogleskintigrafi påviser osteoblastaktivitet og anses for at være yderst...... sensitiv men er ikke særlig specifik. 18F-fluordeoxyglucose (FDG) PET har måske den højeste diagnostiske nøjagtighed for bekræftelse/udelukkelse af kronisk osteomyelitis sammenlignet med knogleskintigrafi, MRI og leukocytskintigrafi. Imidlertid har de fleste studier kun anvendt 18F-FDG PET ved mistanke om...

  12. Blødningsforstyrrelser hos kvinder. Undersøgelse og behandling i almen praksis

    DEFF Research Database (Denmark)

    Astrup, Karen

    1994-01-01

    Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...... konsensuskonferencen "Blødningsforstyrrelser hos kvinder" febr. 1993. Udgivelsesdato: 1994......Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...

  13. Varmepumper i hushald. Analyse av endringar i effektforbruket hos hushald med panelomnar og vedfyring ved installasjon av ulike typar varmepumper

    OpenAIRE

    Øvrebotten, Kristian

    2015-01-01

    Sidan oljekrisa på 1970-talet som førte til ein gradvis overgang frå bruk av oljekjelar og parafinkaminar til panelomnar og varmepumper, har andelen elektrisitet stadig auka mens andelen av olje har vore redusert. Andelen av elektrisitet hos hushalda utgjer i dag om lag 79 % av den samla energibruken hos hushalda i Noreg. Dette høge forbruket av elektrisitet hos hushalda bidreg til å skape problem med høge effekttoppar i kraftnettet som igjen skapar problem for kraftdistributørar og er med...

  14. HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis.

    Directory of Open Access Journals (Sweden)

    Lucia F Zacchi

    Full Text Available Epigenetic mechanisms regulate the expression of virulence traits in diverse pathogens, including protozoan and fungi. In the human fungal pathogen Candida albicans, virulence traits such as antifungal resistance, white-opaque switching, and adhesion to lung cells are regulated by histone deacetylases (HDACs. However, the role of HDACs in the regulation of the yeast-hyphal morphogenetic transitions, a critical virulence attribute of C. albicans, remains poorly explored. In this study, we wished to determine the relevance of other HDACs on C. albicans morphogenesis. We generated mutants in the HDACs HOS1, HOS2, RPD31, and HDA1 and determined their ability to filament in response to different environmental stimuli. We found that while HOS1 and RPD31 have no or a more limited role in morphogenesis, the HDACs HOS2 and HDA1 have opposite roles in the regulation of hyphal formation. Our results demonstrate an important role for HDACs on the regulation of yeast-hyphal transitions in the human pathogen C. albicans.

  15. Intervention rettet mod sproget hos børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2014-01-01

    Sprogniveauet hos børn med autisme er afgørende for deres muligheder for udfoldelse og udvikling, og sproget er et udviklingsområde, der er meget modtageligt for intensiv intervention. Imidlertid modtager danske børn med autisme kun sjældent intensiv intervention rettet mod sproget. De intensive...

  16. Emerging countries’ multinational companies investing in developed countries: at odds with the HOS paradigm?

    Directory of Open Access Journals (Sweden)

    Andreff, Wladimir

    2013-04-01

    Full Text Available The paper analyses the new trend of outward foreign direct investment (FDI by multinational companies from emerging countries, in particular the BRICs, in developed countries to question the applicability of the traditional HOS theoretical framework to this trend. A literature review shows that labour costs do not play any significant role in the first attempts to provide an analytical explanation of this new trend. A HOS equation, amended in order to encompass FDI, is elaborated in order to explain outward FDI from developed to developing and emerging countries based on differences in labour endowment and therefore in wage rates. Step by step, the equation introduces the technological gap, institutions and government policies. Then it is shown that such equation when reversed to explain outward FDI from emerging to developed countries is at odds with the traditional HOS framework. Turning the HOS theory upside down does not help to explain reverse FDI outflows from emerging to developed countries. An alternative approach is called for, in which a labour cost advantage (a lower wage rate than abroad is a home market advantage for emerging countries to invest abroad. A final section provides some empirical examples that labour matters and a lower home wage rate is a decisive comparative advantage for Indian and Chinese multinationals investing in developed countries. Additional evidence shows that the technological gap and the home country’s institutions and government policy matter as well

  17. MULTIDRUG RESISTANT BACTERIA IN A TERTIARY CARE HOS PITAL.

    Directory of Open Access Journals (Sweden)

    Sujata

    2012-12-01

    Full Text Available ABSTRACT: BACKGROUND: Antibiotic resistance is a global problem in the hos pitals as well as in the community. Selection pressure exerted by over use of antimicrobial agents is the commonest predisposing factor of development of resist ance. Problems faced are especially with Methicillin Resistant Staphylococcus aureus (MR SA, Vancomycin Resistant Enterococci (VRE and Multidrug resistant Gram-negative bacilli (MDR-GNB. AIMS: A study was undertaken to find out the prevalence of all bacteri a isolated in this hospital from different specimens, which are resistant to first line antibio tics and their antimicrobial susceptibility pattern with higher antibiotics during a six-month pe riod. MATERIAL AND METHODS: All isolates from different specimens were processed by s tandard techniques and identified by standard biochemical tests. Antibiotic susceptibilit y was performed on Mueller Hinton Agar (MHA by Kirby-Bauer Disc Diffusion Method (KBDDM, according to CLSI guidelines. Those resistant to first line antibiotics were further te sted for higher antibiotics. For Extended Spectrum β -lactamse (ESBL detection, double disc synergy met hod was carried out for all Gram-negative bacilli. RESULTS: Out of 2987 bacteria grown, 904 (30.3% were multi drug resistant bacteria. Resistance to first line antib iotics was 83.4% and resistance to all higher antibiotics tested was 16.6%. Sixty percent of Staph ylococcus aureus was MRSA and all were sensitive to vancomycin. Prevalence of VRE was 5.3 %. Carbapenem resistant Pseudomonas aeruginosa and Acinetobacter species were 19.1% and 9.8% respectively and 10.1% of Klebsiella species was carbapenem resistant. CONCLUSIONS: This study highlights the extensive problem of antibiotic resistance encounter ed in this hospital. Thus, prudent and appropriate uses of antibiotics are required to reduce the emergence of resistance. Each hospital should also have its own antibiotic policy based on the susceptibility pattern of

  18. Hvilken evidens er der for behandling af depression hos børn og unge med kognitiv terapi?

    DEFF Research Database (Denmark)

    Sørensen, Merete Juul; Thomsen, Per Hove

    2007-01-01

    Depression hos børn og unge er relativt hyppigt forekommende og kan have svære konsekvenser. Den specifikke antidepressive behandling kan være psykoterapeutisk eller medikamentel. I artiklen gennemgås på baggrund af systematisk litteratursøgning den videnskabelige evidens for effekten af kognitiv...... adfærdsterapi hos børn og unge med depression....

  19. HOS cell adhesion on Ti6Al4V surfaces texturized by laser engraving

    Science.gov (United States)

    Sandoval Amador, A.; Carreño Garcia, H.; Escobar Rivero, P.; Peña Ballesteros, D. Y.; Estupiñán Duran, H. A.

    2016-02-01

    The cell adhesion of the implant is determinate by the chemical composition, topography, wettability, surface energy and biocompatibility of the biomaterial. In this work the interaction between human osteosarcoma HOS cells and textured Ti6Al4V surfaces were evaluated. Ti6Al4V surfaces were textured using a CO2 laser in order to obtain circular spots on the surfaces. Test surfaces were uncoated (C1) used as a control surface, and surfaces with points obtained by laser engraving, with 1mm spacing (C2) and 0.5mm (C3). The HOS cells were cultured in RPMI-1640 medium with 10% fetal bovine serum and 1% antibiotics. No cells toxicity after one month incubation time occurred. The increased cell adhesion and cell spreading was observed after 1, 3 and 5 days without significant differences between the sample surfaces (C2 and C3) and control (uncoated) at the end of the experiment.

  20. Automatic Detection of Pathologies in The Voice by HOS Based Parameters

    Directory of Open Access Journals (Sweden)

    de Leon José

    2001-01-01

    Full Text Available In the current panorama the conclusive identification of a laryngeal pathology relies inevitably on the observation of the vocal folds by means of laryngoscopical techniques. This inspection technique is inconvenient for a number of reasons, such as its high cost, the duration of the inspection, and, above all, the fact that it is an invasive technique. This paper looks into the possibility of measuring the quality of a voice starting from an audio recording. The existing parameters in current literature ("classic parameters" which allow quantifying the quality of a voice have been studied, and the parameters that present better results have been selected. Also, seven new High Order Statistics (HOS based parameters are proposed to parametrize the voice signal. On the other hand, a software package has been developed which carries out the automatic detection of dysfunction in phonation. A success rate of % has been obtained by using both the classic and the HOS based proposed parameters.

  1. Drænbehandling af recidiverende otitis media hos børn

    DEFF Research Database (Denmark)

    Lous, Jørgen; Trankjær, Christina Ryborg; Thomsen, Janus Laust

    2010-01-01

    I et nyligt publiceret Cochrane-review om effekten af indsættelse af trommehindedræn hos børn med recidiverende akut otitis media (RAOM) fandt man kun to studier, som opfyldte inklusionskriterierne. De inkluderede studier påviste en absolut risikoreduktion for at få AOM på 0,34 på seks måneder. Ved...

  2. At spille med de voksne

    DEFF Research Database (Denmark)

    Thomsen, Kristian Raun

    2015-01-01

    of experience as a coach, player and/or talent manager in Danish and international elite football indicated that resilience, and ability to navigate between discipline and ferocity are vital factors in the pathway to senior elite football, but more importantly to remain there. In addition, the talented player...... will benefit from the ability to act in accordance with senior professional norms. Knowing your own worth, and to some extent to be able to take advantage of an extraordinary talent are regarded virtues in senior elite coaches and managers as well as among athletes that have successfully sustained senior elite......Recent studies have addressed factors important for a talented player’s pathway to senior professional football. However, there is limited focus on the ongoing process where players are trying to gain a foothold in senior elite football, and how the perceived factors are used and understood...

  3. Screening af voksne for ADHD

    DEFF Research Database (Denmark)

    Obel, Carsten; Dalsgaard, Søren; Arngrim, Torben

    2009-01-01

    ADHD is a well established condition in childhood, but much less attention has been given to this diagnosis among adults. It is estimated that 2-4% of the adult population has this condition. Adults with ADHD present symptoms that differ somewhat from those presenting in childhood and they are ty......ADHD is a well established condition in childhood, but much less attention has been given to this diagnosis among adults. It is estimated that 2-4% of the adult population has this condition. Adults with ADHD present symptoms that differ somewhat from those presenting in childhood...... and they are typically characterized by problems with planning of work and daily life activities as well as social persistence. The Adult ADHD Self-report Scale (ASRS) can be used in general practice as an introduction to the diagnostic process of ADHD in a psychiatry setting and to evaluate the effect of treatment...

  4. Screening af voksne for ADHD

    DEFF Research Database (Denmark)

    Obel, Carsten; Dalsgaard, Søren; Arngrim, Torben

    2009-01-01

    ADHD is a well established condition in childhood, but much less attention has been given to this diagnosis among adults. It is estimated that 2-4% of the adult population has this condition. Adults with ADHD present symptoms that differ somewhat from those presenting in childhood...... and they are typically characterized by problems with planning of work and daily life activities as well as social persistence. The Adult ADHD Self-report Scale (ASRS) can be used in general practice as an introduction to the diagnostic process of ADHD in a psychiatry setting and to evaluate the effect of treatment....... ASRS is now available in Danish and is recommended as a screener for adult ADHD. Udgivelsesdato: 2009-Jan-19...

  5. Nyrepåvirkning hos midaldrende og ældre personer med nyopdaget diabetes mellitus. Fra projektet "Diabetesomsorg i almen praksis"

    DEFF Research Database (Denmark)

    Olivarius, Niels de Fine; Andreasen, A.H.

    1994-01-01

    Dette er en formidling af resultaterne fra sidste års artikel angående nyrepåvirknign hos nyopdagede aldersdiabetikere i Diabetologia. Udgivelsesdato: 1994......Dette er en formidling af resultaterne fra sidste års artikel angående nyrepåvirknign hos nyopdagede aldersdiabetikere i Diabetologia. Udgivelsesdato: 1994...

  6. The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.

    Science.gov (United States)

    Elías-Villalobos, Alberto; Fernández-Álvarez, Alfonso; Moreno-Sánchez, Ismael; Helmlinger, Dominique; Ibeas, José I

    2015-08-01

    Morphological changes are critical for host colonisation in plant pathogenic fungi. These changes occur at specific stages of their pathogenic cycle in response to environmental signals and are mediated by transcription factors, which act as master regulators. Histone deacetylases (HDACs) play crucial roles in regulating gene expression, for example by locally modulating the accessibility of chromatin to transcriptional regulators. It has been reported that HDACs play important roles in the virulence of plant fungi. However, the specific environment-sensing pathways that control fungal virulence via HDACs remain poorly characterised. Here we address this question using the maize pathogen Ustilago maydis. We find that the HDAC Hos2 is required for the dimorphic switch and pathogenic development in U. maydis. The deletion of hos2 abolishes the cAMP-dependent expression of mating type genes. Moreover, ChIP experiments detect Hos2 binding to the gene bodies of mating-type genes, which increases in proportion to their expression level following cAMP addition. These observations suggest that Hos2 acts as a downstream component of the cAMP-PKA pathway to control the expression of mating-type genes. Interestingly, we found that Clr3, another HDAC present in U. maydis, also contributes to the cAMP-dependent regulation of mating-type gene expression, demonstrating that Hos2 is not the only HDAC involved in this control system. Overall, our results provide new insights into the role of HDACs in fungal phytopathogenesis.

  7. The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.

    Directory of Open Access Journals (Sweden)

    Alberto Elías-Villalobos

    2015-08-01

    Full Text Available Morphological changes are critical for host colonisation in plant pathogenic fungi. These changes occur at specific stages of their pathogenic cycle in response to environmental signals and are mediated by transcription factors, which act as master regulators. Histone deacetylases (HDACs play crucial roles in regulating gene expression, for example by locally modulating the accessibility of chromatin to transcriptional regulators. It has been reported that HDACs play important roles in the virulence of plant fungi. However, the specific environment-sensing pathways that control fungal virulence via HDACs remain poorly characterised. Here we address this question using the maize pathogen Ustilago maydis. We find that the HDAC Hos2 is required for the dimorphic switch and pathogenic development in U. maydis. The deletion of hos2 abolishes the cAMP-dependent expression of mating type genes. Moreover, ChIP experiments detect Hos2 binding to the gene bodies of mating-type genes, which increases in proportion to their expression level following cAMP addition. These observations suggest that Hos2 acts as a downstream component of the cAMP-PKA pathway to control the expression of mating-type genes. Interestingly, we found that Clr3, another HDAC present in U. maydis, also contributes to the cAMP-dependent regulation of mating-type gene expression, demonstrating that Hos2 is not the only HDAC involved in this control system. Overall, our results provide new insights into the role of HDACs in fungal phytopathogenesis.

  8. HOS AND GA BASED INTERFERENCE REJECTION IN DIRECT SEQUENCE SPREAD SPECTRUM COMMUNICATION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    GongXiangyang; HuGuangrui

    2003-01-01

    A new Higher Order Statistics (OHS) and Genetic Algorithm (GA)-based inter-ference rejection filter is introduced.Compared with the adaptive filters based on second-order statistics and gradient algorithm,the HOS and GA-based filter can reject the interference more efficiently,is independent of uncorrelated Gaussian noise,tende to converge to the optimum solution and is much less sensitive to the choice of the step size parameter.Computer simulations show that the method can reject narrowband interference efficiently.

  9. A HOS-based Blind Signal Extraction Method for Chaotic MIMO Systems

    Institute of Scientific and Technical Information of China (English)

    GONG Yun-rui; HE Di; HE Chen; JIANG Ling-ge

    2008-01-01

    A novel method to extract multiple input and multiple output (MIMO) chaotic signals was pro-posed using the blind neural algorithm after transmitting in nonideal channel. The MIMO scheme with different chaotic signal generators was presented. In order to separate the chaotic source signals only by using the sensor signals at receivers, a blind neural extraction algorithm based on higher-order statistic (HOS) technique was used to recover the primary chaotic signals. Simulation results show that the proposed approach has good performance in separating the primary chaotic signals even under nonideal channel.

  10. Förekomst av karies och parodontit hos personer med Morbus Crohn

    OpenAIRE

    Johansson, Annika; Olsson, Sara

    2012-01-01

    Syftet med litteraturstudien var att undersöka förekomsten av karies och parodontit hos personer med Morbus Crohn. Metoden som användes var en allmän litteraturstudie. Materialet till litteraturstudien samlades in genom sökning i databaserna Cinahl, PubMed och ScienceDirect. De sökord som användes vid litteratursökningen i samtliga databaser var ”caries”, ”Crohn’s disease”, ”periodontal disease” och ”periodontitis”. Vetenskapliga artiklar som fick ingå i litteraturstudien begränsades till ”En...

  11. Functional characterization of Candida albicans Hos2 histone deacetylase [v2; ref status: indexed, http://f1000r.es/3i2

    Directory of Open Access Journals (Sweden)

    G Karthikeyan

    2014-05-01

    Full Text Available Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals. Azoles have been very effective anti-fungal agents and the mainstay in treating opportunistic mold and yeast infections. Azole resistant strains have emerged compromising the utility of this class of drugs. It has been shown that azole resistance can be reversed by the co-administration of a histone deacetylase (HDAC inhibitor, suggesting that resistance is mediated by epigenetic mechanisms possibly involving Hos2, a fungal deacetylase. We report here the cloning and functional characterization of HOS2 (HighOsmolarity Sensitive, a gene coding for fungal histone deacetylase from C. albicans. Inhibition studies showed that Hos2 is susceptible to pan inhibitors such as trichostatin A (TSA and suberoylanilide hydroxamic acid (SAHA, but is not inhibited by class I inhibitors such as MS-275. This in vitro enzymatic assay, which is amenable to high throughput could be used for screening potent fungal Hos2 inhibitors that could be a potential anti-fungal adjuvant. Purified Hos2 protein consistently deacetylated tubulins, rather than histones from TSA-treated cells. Hos2 has been reported to be a putative NAD+ dependent histone deacetylase, a feature of sirtuins. We assayed for sirtuin activation with resveratrol and purified Hos2 protein and did not find any sirtuin activity.

  12. Functional characterization of Candida albicans Hos2 histone deacetylase [v3; ref status: indexed, http://f1000r.es/3xh

    Directory of Open Access Journals (Sweden)

    G Karthikeyan

    2014-07-01

    Full Text Available Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals. Azoles have been very effective anti-fungal agents and the mainstay in treating opportunistic mold and yeast infections. Azole resistant strains have emerged compromising the utility of this class of drugs. It has been shown that azole resistance can be reversed by the co-administration of a histone deacetylase (HDAC inhibitor, suggesting that resistance is mediated by epigenetic mechanisms possibly involving Hos2, a fungal deacetylase. We report here the cloning and functional characterization of HOS2 (HighOsmolarity Sensitive, a gene coding for fungal histone deacetylase from C. albicans. Inhibition studies showed that Hos2 is susceptible to pan inhibitors such as trichostatin A (TSA and suberoylanilide hydroxamic acid (SAHA, but is not inhibited by class I inhibitors such as MS-275. This in vitro enzymatic assay, which is amenable to high throughput could be used for screening potent fungal Hos2 inhibitors that could be a potential anti-fungal adjuvant. Purified Hos2 protein consistently deacetylated tubulins, rather than histones from TSA-treated cells. Hos2 has been reported to be a putative NAD+ dependent histone deacetylase, a feature of sirtuins. We assayed for sirtuin activation with resveratrol and purified Hos2 protein and did not find any sirtuin activity.

  13. HosA, a MarR Family Transcriptional Regulator, Represses Nonoxidative Hydroxyarylic Acid Decarboxylase Operon and Is Modulated by 4-Hydroxybenzoic Acid.

    Science.gov (United States)

    Roy, Ajit; Ranjan, Akash

    2016-02-23

    Members of the Multiple antibiotic resistance Regulator (MarR) family of DNA binding proteins regulate transcription of a wide array of genes required for virulence and pathogenicity of bacteria. The present study reports the molecular characterization of HosA (Homologue of SlyA), a MarR protein, with respect to its target gene, DNA recognition motif, and nature of its ligand. Through a comparative genomics approach, we demonstrate that hosA is in synteny with nonoxidative hydroxyarylic acid decarboxylase (HAD) operon and is present exclusively within the mutS-rpoS polymorphic region in nine different genera of Enterobacteriaceae family. Using molecular biology and biochemical approach, we demonstrate that HosA binds to a palindromic sequence downstream to the transcription start site of divergently transcribed nonoxidative HAD operon and represses its expression. Furthermore, in silico analysis showed that the recognition motif for HosA is highly conserved in the upstream region of divergently transcribed operon in different genera of Enterobacteriaceae family. A systematic chemical search for the physiological ligand revealed that 4-hydroxybenzoic acid (4-HBA) interacts with HosA and derepresses HosA mediated repression of the nonoxidative HAD operon. Based on our study, we propose a model for molecular mechanism underlying the regulation of nonoxidative HAD operon by HosA in Enterobacteriaceae family.

  14. Psykisk helsearbeid på internett: konsekvenser for normalitets- og identitetsdannelse hos ungdom

    Directory of Open Access Journals (Sweden)

    Anders Johan W. Andersen

    2011-03-01

    Full Text Available Psykisk helsearbeid på internett øker i omfang, og verdsettes på grunn av bekvemmelighet, lave kostnader og muligheter for anonymitet. Artikkelen bygger på en kartlegging av norske og svenske nettbaserte eposttjenester for ungdom og unge voksne, og viser at det var 24 nettsteder som tilbød slike tjenester i 2009. Tjenestene hadde opphav i både offentlig og frivillig sektor. Flesteparten av sidene fra offentlig sektor tok utgangspunkt i eksisterende tjenestetilbud, og var en videreutvikling av tjenestene for å styrke tilgjengeligheten av psykisk helsetjenester. Andre sider oppsto som en konsekvens av FNs konvensjon av barns rettigheter. Størsteparten av sidene fra frivillig sektor ble utviklet som følge av et personlig og/eller fagpolitisk engasjement. Fire hovedtema for e-posttjenestene ble identifisert: 1 Kropp, kjønn og seksuell helse; 2 Informasjon og kontakt med voksne; 3 Rus og rusmidler; 4 Psykiske problemer. Studien viser at nettjenestene argumenterer for at det er viktig for ungdoms psykiske helse at de blir inkludert og akseptert i et fellesskap og at de opplever å bli respektert på egne premisser. Samtidig videreføres et ideal om det uavhengige og autonome mennesket, og nettjenestene formidler samlet sett et spenningsfylt budskap om at ungdom er avhengige av andre for å bli og forbli uavhengige individer. Psykisk helsearbeid på internett framstår som en måte å håndtere denne spenningen på, og muliggjør at ungdom kan håndtere en identitet som både avhengige og uavhengige mennesker. Studien viser forskjeller knyttet til begrepsforståelse, og peker på viktigheten av å utforske meningsinnholdet i psykisk helse nærmere.Mental health services on the Internet.ENGLISH SUMMARY: The demand for Internet-based mental health services are increasing. The services are valued for their convenience, low cost and opportunities for anonymity. This article is based on a survey of Norwegian and Swedish Internet-based email

  15. Daphnoretin Induces Cell Cycle Arrest and Apoptosis in Human Osteosarcoma (HOS Cells

    Directory of Open Access Journals (Sweden)

    Jinhai He

    2012-01-01

    Full Text Available In this study antiproliferation, cell cycle arrest and apoptosis induced by daphnoretin in human osteosarcoma (HOS cells were investigated. Antiproliferative activity was measured with the 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay. The IC50 value of daphnoretin was 3.89 μM after 72 h treatment. Induction of apoptosis was evidenced by apoptotic body appearance and Annexin V-FITC/PI apoptosis detection kit. Flow cytometric analysis indicated daphnoretin arrested the cell cycle in the G2/M phase. Western-blot assay showed that the G2/M phase arrest was accompanied by down-regulation of cdc2, cyclin A and cyclin B1. Moreover, daphnoretin inhibited Bcl-2 expression and induced Bax expression to desintegrate the outer mitochondrial membrane and causing cytochrome c release. Mitochondrial cytochrome c release was associated with the activation of caspase-9 and caspase-3 cascade. Our results demonstrated that daphnoretin caused death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.

  16. 76 FR 16852 - Hours of Service (HOS) of Drivers; Assessing the Safety Impact of the Exemption From the 14-Hour...

    Science.gov (United States)

    2011-03-25

    ... Pyrotechnics Association (APA) an exemption from the current HOS prohibition against driving a commercial motor...: Thomas Yager, FMCSA Driver and Carrier Operations Division; Office of Bus and Truck Standards and... 381.300(b)). APA's Independence Day Operations and the Exemption from 49 CFR 395.3(a)(2) APA is...

  17. Expression, Functional Characterization and X-ray Analysis of HosA, A Member of MarR Family of Transcription Regulator from Uropathogenic Escherichia coli.

    Science.gov (United States)

    Roy, Ajit; Reddi, Ravikumar; Sawhney, Bhavik; Ghosh, Debasish Kumar; Addlagatta, Anthony; Ranjan, Akash

    2016-08-01

    Regulators belonging to multiple antibiotic resistance regulator (MarR) family are widespread in prokaryotes and are involved in regulation of genes that are responsible for virulence and pathogenicity in most of the clinically important pathogens. Here we report the transcriptional, biophysical, and X-ray analyses of homologue of SlyA (HosA), a member of MarR family that is predominantly present in the pathogenic strains of Enterobacteriaceae family. The initiation of hosA transcription was observed to occur at two independent start sites and subsequent binding study has revealed that the purified HosA interacts with its upstream region suggesting a probable autoregulation. The secondary structure analysis through circular dichroism spectroscopy demonstrated that HosA is predominantly composed of the alpha helix with higher thermal stability. To further understand the three-dimensional structure, HosA was crystallized and the crystals were diffracted to maximum of 2.9 Ǻ on exposure to X-rays. Analysis of the X-ray crystallographic data suggested a primitive space group (P 6 ? 2 2), with unit cell parameters a = b = 64.19 Å and c = 244.25 Å. The solvent content and Matthews coefficient were 41 % and 2.11 Å(3) Da(-1), respectively, which indicated the existence of two molecules of HosA in the asymmetric unit of crystal.

  18. Att stärka delaktigheten hos barn med autism på daghem : En litteraturstudie

    OpenAIRE

    Rikberg, Sofie

    2012-01-01

    Idag strävas det efter att barn med lindrigare former av autism så långt som möjligt skall integreras i daghem. På grund av de svårigheter som barnet med autism har löper det risk att bli utanför gemenskapen på daghemmet. Examensarbetet beskriver i form av en litteraturstudie beskriva hur de professionella kan stärka delaktigheten hos barn med autism på daghem och därmed främja möjligheterna till social inklusion. Frågeställningen är följande: Hur kan professionella forma verksamheten på dag...

  19. DCS系统在6HOS-3型往复压缩机上的应用%Application of DCS System in 6HOS-3 Type Reciprocating Compressor

    Institute of Scientific and Technical Information of China (English)

    王玮

    2012-01-01

    为了提高往复压缩机的仪表自动化控制水平,以天然气处理站液化气回收装置引进的6HOS-3型往复压缩机为例,在不改变压缩机控制逻辑的基础上,把DCS系统应用到往复压缩机的参数监控和数据分析上,并取得了很好的效果.%In order to improve the automation control level of the reciprocating compressor instruments, set the introduced 6HOS-3type reciprocating compressor in the natural gas processing station of liquefied petroleum gas recovery device for an example,without changing the control logic,the DCS system is applied to the reciprocating compressor parameter monitoring and data analysis,and the good results are achieved.

  20. HOS3, an ELO-Like Gene, Inhibits Effects of ABA and Implicates a S-1-P/Ceramide Control System for Abiotic Stress Responses in Arabidopsis thaliana

    Institute of Scientific and Technical Information of China (English)

    Tanya M. Quist; Irina Sokolchik; Huazhong Shi; Robert J. Joly; Ray A. Bressan; Albino Maggio; Meena Narsimhan; Xia Li

    2009-01-01

    A hyper-osmotically sensitive mutant of Arabidopsis thaliana, designated hos3-1 (high expression of osmotically responsive genes), was identified based on its hyper-luminescence of RD29A:LUC promoter fusion plants upon treatment with NaCI and ABA. These responses implicate the disrupted gene as a direct or indirect negative regulator of the RD29A stress-responsive pathway. By sequencing the flanking regions of the T-DNA borders, it was determined that the disrupted gene is at locus At4g36830, annotated as encoding a putative protein with high homology to CIG30 (ELO2/FEN1).CIG30 has been implicated in synthesis of very long chain fatty acids (VLCFA), which are essential precursors for sphingolipids and ceramides. Altered stress responses characteristic of ABA-hypersensitivity, including reduced root growth inhibition and reduced germination with ABA treatment and reduced water loss from leaves, were exhibited by allelic hos3-1 and hos3-2 mutants. The hos3-2 mutant is partially suppressed in its transcript abundance and is inherited as a recessive trait. Further, the HOS30RF under the control of the 35SCaMV promoter restored wild-type NaCI- and ABA-root growth sensitivity as well as RD29A:LUC luminescence in mutant plants. We also show here that the HOS3 wild-type gene functionally complements the sensitivity of elo2 and elo3 yeast mutants to monensin. Furthermore, both hos3-1 and hos3-2 alleles shared increased sensitivity to the herbicide Metolachlor, which inhibits acyl chain elongation in synthesis of VLCFA, and HOS3 functionally complemented both elo2 and elo3 and restored levels of VLCFA. Together, these data establish that HOS3 inhibits ABA-mediated stress responses and implicate the VLCFA pathway and products as control points for several aspects of abiotic stress signaling and responses. The results also provide support for a role of ceramide in the control of stomatal behavior.

  1. Sprogtilegnelse hos normalthørende og hørehæmmede børn

    DEFF Research Database (Denmark)

    Højen, Anders

    2011-01-01

    ”Whisper-projekt” ved Center for Børnesprog, Syddansk Universitet, har fokuseret på den tidlige perception af sproglyde hos normalthørende og hørehæmmede danske børn. Her præsenteres resultater indenfor diskrimination (både normalthørende og hørehæmmede), identifikation af sproglyde (normalthørende...

  2. Development and Validation of Written Exam Items for the Agricultural Hazardous Occupations Orders (AgHOs) Certification Training Program.

    Science.gov (United States)

    Mann, A J; Field, W E; Tormoehlen, R; French, B F

    2016-04-01

    Research was conducted to develop and validate a pool of exam items that can be used to test the readiness of youth, ages 14-15 years, to be certified under the current federally mandated Agricultural Hazardous Occupations Orders (AgHOs). The AgHOs require training prior to employment in agricultural workplaces that the Secretary of Labor has determined are especially hazardous for youth within the prescribed age range. Under the current provisions of the AgHOs certification process, non-exempt youth seeking employment in agriculture are required to pass a written exam concentrating on safe work practices as partial satisfaction to receive certification of eligibility for employment to perform certain tasks. However, the regulations provide little guidance concerning the format of the exam, subject matter to be covered, degree of difficulty, or minimum passing score. As part of the USDA-sponsored Hazardous Occupations Safety Training in Agriculture (HOSTA) initiative, efforts have been made to develop consistent and evidence-based testing methods for disseminating the test protocols to instructors. The goal was to expand, enhance, and maintain the reliability of the exam item pool for the AgHOs certification process. Item development was based on the HOSTA-supported Gearing Up for Safety: Production Agriculture Safety Training for Youth curriculum. To ensure adequate item availability, the current item pool was expanded to include a minimum of two test items for each of the 157 cognitive-based core competencies developed as part of the Gearing Up curriculum design process. Administering 70-item exams that were generated from the item pool to 568 youth, ages 13-18 years, provided evidence of item validity. The result was a pool of 367 validated exam items.

  3. On the Detectability of the X 2A" HSS, HSO, and HOS Radicals in the Interstellar Medium

    Science.gov (United States)

    Fortenberry, Ryan C.; Francisco, Joseph S.

    2017-02-01

    {\\tilde{X}}2A\\prime\\prime HSS has yet to be observed in the gas phase in the interstellar medium (ISM). HSS has been observed in cometary material and in high abundance. However, its agglomeration to such bodies or dispersal from them has not been observed. Similarly, HSO and HOS have not been observed in the ISM, either, even though models support their formation from reactions of known sulfur monoxide and hydrogen molecules, among other pathways. Consequently, this work provides high-level, quantum chemical rovibrational spectroscopic constants and vibrational frequencies in order to assist in interstellar searches for these radical molecules. Furthermore, the HSO‑HOS isomerization energy is determined to be 3.63 kcal mol‑1, in line with previous work, and the dipole moment of HOS is 36% larger at 3.87 D than HSO, making the less stable isomer more rotationally intense. Finally, the S‑S bond strength in HSS is shown to be relatively weak at 30% of the typical disulfide bond energy. Consequently, HSS may degrade into SH and sulfur atoms, making any ISM abundance of HSS likely fairly low, as recent interstellar surveys have observed.

  4. Density functional theory and the correlation consistent basis sets: the tight d effect on HSO and HOS.

    Science.gov (United States)

    Wang, Nick X; Wilson, Angela K

    2005-08-18

    The HSO and HOS isomers have been revisited using the DFT functionals, B3LYP, B3PW91, and PBE, in combination with tight d-augmented correlation consistent basis sets, cc-pV(x+d)Z and aug-cc-pV(x+d)Z for second-row atoms. Structures, vibrationally averaged structures, relative energies, harmonic and anharmonic frequencies, enthalpies of formation of HSO and HOS, and the barrier for the HSO/HOS isomerization have been determined. These results were compared with results from previous DFT and ab initio studies in which the standard correlation consistent basis sets were used. The relative energies of the two isomers converge more rapidly and smoothly with respect to increasing basis set size for the tight d-augmented sets than for the standard basis sets. Our best calculations, B3PW91/aug-cc-pV(5+d)Z, for the relative energy of the isomers are in excellent agreement with previous CCSD(T) results given by Wilson and Dunning.

  5. Identifying depression among adolescents using three key questions

    DEFF Research Database (Denmark)

    Haugen, Wenche; Haavet, Ole Rikard; Sirpal, Manjit Kaur

    2016-01-01

    Depression rammer mange voksne mennesker. Dette studie, som er omtalt i BMJ, viser, at et spørgeskema med blot tre spørgsmål ret præcist kan identificere voksne med depression. Undersøgelsen viser også, at de samme spørgsmål med fordel kan stilles verbalt ved diagnosticering af depression hos ung...

  6. Detection of Disturbances in Voltage Signals for Power Quality Analysis Using HOS

    Directory of Open Access Journals (Sweden)

    Pereira José Luiz R

    2007-01-01

    Full Text Available This paper outlines a higher-order statistics (HOS-based technique for detecting abnormal conditions in voltage signals. The main advantage introduced by the proposed technique refers to its capability to detect voltage disturbances and their start and end points in a frame whose length corresponds to, at least, samples or of the fundamental component if a sampling rate equal to Hz is considered. This feature allows the detection of disturbances in submultiples or multiples of one-cycle fundamental component if an appropriate sampling rate is considered. From the computational results, one can note that almost all abnormal and normal conditions are correctly detected if s256, 128, 64, 32, and 16 and the SNR is higher than 25 dB. In addition, the proposed technique is compared to a root mean square (rms-based technique, which was recently developed to detect the presence of some voltage events as well as their sources in a frame whose length ranges from up to one-cycle fundamental component. The numerical results reveal that the proposed technique shows an improved performance when applied not only to synthetic data, but also to real one.

  7. HOS cell adhesion on TiO2 nanotubes texturized by laser engraving

    Science.gov (United States)

    Sandoval Amador, A.; Montañez Supelano, N. D.; Arias, A. M. Vera; Escobar Rivero, P.; Peña Ballesteros, D. Y.

    2017-01-01

    Due to its outstanding properties, the titanium and its alloys have been widely used in the dental and orthopaedic fields as biomaterials. The TiO2 nanotubes surface and the texturized process by laser engraving enables significantly accelerated osteoblast adhesion on the biomaterial. For this reason in this paper, the HOS cell responses on TiO2 nanotubes fabricated on Ti6Al4V alloy and texturized by laser engraving were evaluated. The test surfaces were carried out on smooth Ti6Al4V as control, TiO2 nanotubes (NT) and surfaces with micropoints obtained by laser engraving, with 1mm spacing (NTP1) and 0.5mm (NTP2). The results show that the texturized process enables decreases the contact angle thus improving wettability of the TiO2 nanotubes surface. The NTP1 and NTP2 surfaces show excellent cell adhesion and spreading on the surface, which is evident in epifluorescence microscopy images. Furthermore, the NTP1 and NTP2 surfaces improved the cell proliferation at 18% and 16% respectively in relation with NT surface, showing that the laser texturing improves cell response of TiO2 nanotubes.

  8. Betydningen af Lawsonia og PCV2 virus for daglig tilvækst hos slagtesvin

    DEFF Research Database (Denmark)

    Johansen, Markku; Nielsen, Mai Britt Friis; Dahl, Jan

    Resultaterne af denne undersøgelse viser at: - Grise med store mængder Lawsonia i gødningen (≥106/gram gødning) har større risiko (OR=5,2) for at være en langsomt voksende gris. - Grise med synlige tarmforandringer har større risiko (OR=13,2) for at være en langsomt voksende gris. - Grise med...... diarré har større risiko (OR=10,1) for at være en langsomt voksende gris. Derimod kunne der ikke påvises nogen sammenhæng mellem mængden af PCV2 virus, antistoffer mod PCV2 virus eller påvisning af PCV2 virus ved immunhistokemi i tarmlymfeknude og tilvæksten hos grise. Undersøgelsen er gennemført i 5...... virus og Lawsonia på DTU-Veterinærinstitutet. For hver gris blev den maksimalt målte værdi af Lawsonia og PCV2 virus mængde i gødning og antistoffer mod de to sygdomme brugt som forklarende variabel. Sammenhængen til hurtigt/langsomt voksende grise for de maksimalt målte værdier blev undersøgt ved...

  9. Kønsudvikling hos sønner af gartneriansatte kvinder

    DEFF Research Database (Denmark)

    Andersen, Helle Raun; Schmidt, Ida Maria; Grandjean, Philippe

    2008-01-01

      Flere pesticider er vist at være hor­mon­for­styr­rende i celle- eller dyreforsøg og epi­de­mio­lo­gi­ske undersøgelser tyder på, at tidlig eks­po­ne­ring for pesticider kan påvirke ud­vik­lingen af for­plantnings- og hor­mon­syste­met hos men­ne­sker. Formålet med denne prospektive under...... før og i star­ten af gra­viditeten arbejdet i områder med pes­ti­cid­anvendelse, mens mødrene til de sid­ste 22 drenge ikke var erhvervsmæssigt eks­­po­ne­ret. Vi fandt flere drenge end for­ven­tet med kryptorkisme (manglende ned­sænk­ning af tes­tiklerne). [1]Desuden havde drenge, hvis mød­re havde...

  10. Gir tidlig vurdering og behandling hos spesialist i fysikalsk medisin og rehabilitering reduksjon i langtidsfravær hos sykmeldte med muskel- og skjelettsykdommer?

    Directory of Open Access Journals (Sweden)

    Harald Elvsåshagen

    2010-01-01

    Full Text Available Bakgrunn: De fleste langtidssykmeldte med muskel- og skjelettsykdommer blir utredet, behandlet og fulgt opp av fastlege. Ved lengre tids sykmelding henvises mange fra sin fastlege til spesialist i fysikalsk medisin og rehabilitering for å optimalisere behandlingsopplegget.Formålet med denne studien var å undersøke om henvisning direkte fra NAV til spesialist uten å gå veien om fastlege, medførte redusert antall sykmeldingsdager og mindre bruk av andre trygdeytelser som rehabiliteringspenger, yrkesrettet attføring og uførepensjon.Materiale og metode: I samarbeid med 14 NAV-kontor i Vestfold ble 829 sykmeldte i alder 25-50 år med 8-12 ukers sykmelding for muskel- og skjelettsykdommer randomisert til en intervensjonsgruppe (n=409 og en kontrollgruppe (n=420. Eksklusjonskriterier var manglende arbeidsforhold, revmatiske sykdommer, brudd og leddsykdommer. Intervensjonsgruppen ble undersøkt og behandlet av spesialist i fysikalsk medisin og rehabilitering, Spesialsykehuset for rehabilitering, avd. Stavern. Kontrollgruppen fortsatte behandling hos sin fastlege. Noen av disse pasientene ble henvist til samme poliklinikk eller til annen spesialist på initiativ fra sin fastlege. Data for sykmeldingsdager, uførepensjon, rehabiliteringspenger og attføringspenger ble samlet inn fra NAV-kontorene. De samme parametre ble brukt som endepunkter. Etter to år ble endepunktene analysert. Data ble analysert etter "intention to treat"- prinsippet.Resultater: I intervensjonsgruppen var gjennomsnittlig antall sykmeldingsdager 138 dager (SD 86,2 mot 147 dager (SD 88,0 i kontrollgruppen, en forskjell på ni sykmeldingsdager. Forskjellen er ikke statistisk signifikant (p=0,163. Det var heller ikke statistisk signifikant forskjell i forbruket av yrkesrettet attføring og rehabiliteringspenger mellom intervensjonsgruppen og behandlingsgruppen.Konklusjon: Henvisning til spesialist i fysikalsk medisin og rehabilitering direkte fra NAV etter 8-12 ukers sykmelding

  11. Brukertilfredshet og livskvalitet hos brukere av elektrisk rullestol : undersøkt med QUEST 2.0 og QOLS - en tverrsnittstudie

    OpenAIRE

    Kateraas, Liv Hege

    2010-01-01

    Formål: Formålet med studien er å undersøke brukertilfredshet hos et utvalg brukere av elektrisk rullestol (N=109). Studien undersøker også sammenhengen mellom brukertilfredshet og livskvalitet hos denne gruppen. Brukertilfredshet blir sett på som et sentralt effektmål. Det er behov for økt kunnskap om brukertilfredshet for å kunne vurdere hjelpemidler som en samfunnsmessig innsats. Teori: Det er tatt utgangspunkt i litteratur som omhandler funksjonshemming, brukertilfredshet, gener...

  12. Preliminær rapport fra forsøk med dekontaminering av radiocesium hos sauelam - Sammendrag

    Directory of Open Access Journals (Sweden)

    Øystein Fæstø

    1986-06-01

    Full Text Available I motsetning til de andre radionukleidene i nedfallet etter hendelsen i Tsjernobyl kan cesium-134 og cesium-137 akkumuleres i muskelvev, lever og nyrer og dermed føre til betydelige næringsmiddeltoksikologiske problemer. Oral dosering av uløselig prøysserblått, fernferrocyanid, er av betydelig interesse som middel til dekontaminering av drøvtyggere for l34Cs og 137Cs ved at opptak av radiocesium fra for og beite kan reduseres eller forhindres, og ved at den biologiske halveringstiden for radiocesium hos dyrene kan forkortes. Bindingsmekamsmen hos uløselig prøysserblått for cesium i fordøyelseskanalen synes å være så selektiv at kalsiummetabolismen ikke blir påvirket i vesentlig grad. Det er imidlertid viktig å være klar over at flere typer prøysserblått, løselige og uløselige, og også flere prøysserblåttanaloger blant ferrocyanidene, har evne til å binde cesium. Men bare bruk av det uløselige prøysserblått eller ferriferrocyanid kan, ut fra den kunnskap som foreligger, vurderes å medføre minimal næringsmiddeltoksikologisk risiko.

  13. fau and its ubiquitin-like domain (FUBI) transforms human osteogenic sarcoma (HOS) cells to anchorage-independence.

    Science.gov (United States)

    Rossman, Toby G; Visalli, Melissa A; Komissarova, Elena V

    2003-03-27

    Arsenite is the most likely carcinogenic form of arsenic in the environment. Previously, expression cloning for cDNAs whose overexpression confers arsenite-resistance in Chinese hamster V79 cells identified two genes: fau and a novel gene, asr2. The fau gene encodes a ubiquitin-like protein (here called FUBI) fused to the ribosomal S30 protein. Since the expression of the fox sequence (antisense to fau) increased the tumorigenicity of a mouse sarcoma virus, it was proposed that fau might be a tumor suppressor gene. We intended to test its ability to block arsenite-induced transformation of human osteogenic sarcoma (HOS) cells to anchorage-independence. Instead, we found that overexpressing fau itself was able to transform HOS cells. When the two domains were expressed separately, only FUBI was transforming and only the S30 domain conferred arsenite resistance. An incidental finding was the transforming activity of the selectable marker, hyg. FUBI belongs to the ubiquitin-like protein group that is capable of forming conjugates to other proteins, although none have so far been identified. Alternatively, FUBI may act as a substitute or inhibitor of ubiquitin, to which it is most closely related, or to close ubiquitin-like relatives UCRP, FAT10, and/or Nedd8.

  14. Comparative studies of genome-wide maps of nucleosomes between deletion mutants of elp3 and hos2 genes of Saccharomyces cerevisiae.

    Directory of Open Access Journals (Sweden)

    Takashi Matsumoto

    Full Text Available In order to elucidate the influence of histone acetylation upon nucleosomal DNA length and nucleosome position, we compared nucleosome maps of the following three yeast strains; strain BY4741 (control, the elp3 (one of histone acetyltransferase genes deletion mutant, and the hos2 (one of histone deactylase genes deletion mutant of Saccharomyces cerevisiae. We sequenced mononucleosomal DNA fragments after treatment with micrococcal nuclease. After mapping the DNA fragments to the genome, we identified the nucleosome positions. We showed that the distributions of the nucleosomal DNA lengths of the control and the hos2 disruptant were similar. On the other hand, the distribution of the nucleosomal DNA lengths of the elp3 disruptant shifted toward shorter than that of the control. It strongly suggests that inhibition of Elp3-induced histone acetylation causes the nucleosomal DNA length reduction. Next, we compared the profiles of nucleosome mapping numbers in gene promoter regions between the control and the disruptant. We detected 24 genes with low conservation level of nucleosome positions in promoters between the control and the elp3 disruptant as well as between the control and the hos2 disruptant. It indicates that both Elp3-induced acetylation and Hos2-induced deacetylation influence the nucleosome positions in the promoters of those 24 genes. Interestingly, in 19 of the 24 genes, the profiles of nucleosome mapping numbers were similar between the two disruptants.

  15. Når alderen indhenter én. Kropslighed, aldring og profession hos gymnasiets idrætslærere. Ph.d. afhandling

    DEFF Research Database (Denmark)

    Christensen, Mette Krogh

    Når alderen indhenter én – om kropslighed, aldring og profession hos gymnasiets idrætslærere er en ph.d.-afhandling udarbejdet af Mette Krogh Christensen på Institut for Idræt (Afdeling for Historie og Samfundsvidenskab), Københavns Universitet. Afhandlingen handler om, på hvilken måde alder spil...

  16. Cochleaimplantat til døve voksne

    DEFF Research Database (Denmark)

    Wanscher, Jens Højberg; Faber, Christian Emil; Grøntved, Aksel Møller

    2006-01-01

    INTRODUCTION: Our aim was to assess the effect of cochlear implant (CI) surgery on the mental quality of life in totally deaf adults using a generic type of questionnaire. MATERIALS AND METHODS: The survey comprised 40 adult CI users who answered a standard and a retrospective version of the Short...... the mean scores of the equivalent subscales of the Danish population, whereas the post-implant mean scores in two out of three cases were above the mean scores of the Danish population. DISCUSSION: CI was shown to have a statistically significant positive impact on the quality of life of adult deaf...

  17. Insulinbehandling af voksne med type 1-diabetes

    DEFF Research Database (Denmark)

    Pedersen-Bjergaard, Ulrik; Thorsteinsson, Birger

    2015-01-01

    Whereas insulin treatment of type 1 diabetes formerly was limited by the availability of one or a few types of insulin with suboptimal pharmacokinetic properties, insulin analogues with more fitting physiological action profiles have now been developed and ultimately near-physiological insulin...... treatment can be delivered with insulin pumps. Adjustments of insulin dosing can be rationally based on dosing algorithms. This requires frequent glucose measurements and knowledge about dietary carbohydrate content. Today, the treatment and its complexity are individualized according to needs and wishes...

  18. Usikker effekt af influenzavaccination af raske voksne

    DEFF Research Database (Denmark)

    Pedersen, Louise Ørnskov; Lund, Katrine Bak; Nielsen, Tine Jepsen;

    2012-01-01

    At some Danish workplaces, healthy employees are offered an influenza vaccination, although vaccination has not been proven to have a protective effect on healthy adults. This article gives an overview of the effect of influenza vaccination on healthy adults based on the results from the Cochrane...... review "Vaccines for preventing influenza in healthy adults" and new studies in the field of interest. These studies show a limited effect on influenza, influenza-like illness, lost workdays, physician visits and days of illness....

  19. Usikker effekt af influenzavaccination af raske voksne

    DEFF Research Database (Denmark)

    Pedersen, Louise Ørnskov; Lund, Katrine Bak; Nielsen, Tine Jepsen

    2012-01-01

    At some Danish workplaces, healthy employees are offered an influenza vaccination, although vaccination has not been proven to have a protective effect on healthy adults. This article gives an overview of the effect of influenza vaccination on healthy adults based on the results from the Cochrane...... review "Vaccines for preventing influenza in healthy adults" and new studies in the field of interest. These studies show a limited effect on influenza, influenza-like illness, lost workdays, physician visits and days of illness....

  20. Undervisningsfaget dansk som andetsprog for voksne

    DEFF Research Database (Denmark)

    Petersen, Karen Bjerg

    2003 kan identificeres en national- og monokulturel diskurs, en arbejdslivskvalificerende diskurs og en neoliberal diskurs. Det diskuteres, hvordan disse forskellige læreplansdiskurser understøttes af forskellige magt-, beherskelses- og legitimeringssystemer. Det teoretiske grundlag for diskussionen...

  1. Insulinbehandling af voksne med type 1-diabetes

    DEFF Research Database (Denmark)

    Pedersen-Bjergaard, Ulrik; Thorsteinsson, Birger

    2015-01-01

    treatment can be delivered with insulin pumps. Adjustments of insulin dosing can be rationally based on dosing algorithms. This requires frequent glucose measurements and knowledge about dietary carbohydrate content. Today, the treatment and its complexity are individualized according to needs and wishes......Whereas insulin treatment of type 1 diabetes formerly was limited by the availability of one or a few types of insulin with suboptimal pharmacokinetic properties, insulin analogues with more fitting physiological action profiles have now been developed and ultimately near-physiological insulin...

  2. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 2 Leg 1, collected from 2010-08-26 to 2010-09-02, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0128093)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 02, to determine physical oceanographic parameters of the water...

  3. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 1 Leg 1, collected from 2010-08-13 to 2010-08-22, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0128072)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 01, to determine physical oceanographic parameters of the water...

  4. Framtida förändringar i konstruktionen hos fordon som en följd av autonoma system

    OpenAIRE

    Didner, Olof; Ingvarsson, Gustaf

    2015-01-01

    Detta är ett kandidatexamensarbete om hur självkörande bilar kan se ut i framtiden. Utgående från dagens bilar och nuvarande autonoma hjälpsystem, samt system som är under utveckling och prototypbilar som företag har, dras slutsatser om hur konstruktionen hos framtida bilar kan skilja sig från idag. För att underlätta detta togs olika krav fram, som kan ställas på självkörande bilar. Dessa krav rör bland annat manövrering, uppsikt runt fordonet, oskyddade trafikanter, olika väderförhållanden ...

  5. Reversion effects of curcumin on multidrug resistance of MNNG/HOS human osteosarcoma cells in vitro and in vivo through regulation of P-glycoprotein

    Institute of Scientific and Technical Information of China (English)

    SI Meng; ZHAO Jie; LI Xin; TIAN Ji-guang; LI Yong-gang; LI Jian-min

    2013-01-01

    Background P-glycoprotein (P-gp) encoded by ATP-binding cassette sub-family B member 1 (ABCB1) gene is a kind of ATP-dependent drug transporter,which plays important roles in multidrug resistance (MDR) of human cancers,such as osteosarcoma.Curcumin is a natural phenolic coloring compound originating from the rhizomes of Curcuma longa,which is proved to possess antitumor biological activities including reversion of MDR.However,the effect and molecular mechanisms of curcumin to osteosarcoma MDR remain unclear.Methods We established a human osteosarcoma drug-resistant cell line MNNG/HOS/MTX by pulse exposure to methotrexate (MTX) and verified that the new cell lines were cross-resistant to other anticancer agents.Then,according to the cytotoxicity assay,we reversed MDR of MNNG/HOS/MTX by 30 μmol/L curcumin,and detected the mechanisms of curcumin reversing MDR through Real-time PCR,Western blotting assay,and Rhodamine123 (Rh123)transport test.Finally,we evaluated the effect of curcumin reversing MDR in vivo by MNNG/HOS/MTX cells xenograft-nude mice model.Results MNNG/HOS/MTX was proved to be a human osteosarcoma MDR cell line.MTT tumor chemosensitivity test indicates that 30 μmol/L curcumin attenuates the half maximal inhibitory concentration (IC50) and resistance index (RI)to MTX,diamminedichloroplatinum (DDP),adriamycin (ADM),ifosfamide (IFO),and epirubicin (EPI) in MNNG/HOS/MTX cells (P <0.05).Real-time PCR and Western blotting assays demonstrated that curcumin down-regulated P-gp expression of MNNG/HOS/MTX cells.Rh123 transport test showed that curcumin inhibited the transport function of P-gp in vitro.In vivo studies showed that curcumin displayed the features of sensitizing antitumor drugs and inhibiting the proliferation,invasion,and metastasis of osteosarcoma MDR cells.Conclusion Down-regulation of P-gp and inhibition of the function of P-gp efflux pump may contribute to MDR reversion induced by curcumin in vitro and in vivo.

  6. Computer-aided diagnosis of Myocardial Infarction using ultrasound images with DWT, GLCM and HOS methods: A comparative study.

    Science.gov (United States)

    Vidya, K Sudarshan; Ng, E Y K; Acharya, U Rajendra; Chou, Siaw Meng; Tan, Ru San; Ghista, Dhanjoo N

    2015-07-01

    Myocardial Infarction (MI) or acute MI (AMI) is one of the leading causes of death worldwide. Precise and timely identification of MI and extent of muscle damage helps in early treatment and reduction in the time taken for further tests. MI diagnosis using 2D echocardiography is prone to inter-/intra-observer variability in the assessment. Therefore, a computerised scheme based on image processing and artificial intelligent techniques can reduce the workload of clinicians and improve the diagnosis accuracy. A Computer-Aided Diagnosis (CAD) of infarcted and normal ultrasound images will be useful for clinicians. In this study, the performance of CAD approach using Discrete Wavelet Transform (DWT), second order statistics calculated from Gray-Level Co-Occurrence Matrix (GLCM) and Higher-Order Spectra (HOS) texture descriptors are compared. The proposed system is validated using 400 MI and 400 normal ultrasound images, obtained from 80 patients with MI and 80 normal subjects. The extracted features are ranked based on t-value and fed to the Support Vector Machine (SVM) classifier to obtain the best performance using minimum number of features. The features extracted from DWT coefficients obtained an accuracy of 99.5%, sensitivity of 99.75% and specificity of 99.25%; GLCM have achieved an accuracy of 85.75%, sensitivity of 90.25% and specificity of 81.25%; and HOS obtained an accuracy of 93.0%, sensitivity of 94.75% and specificity of 91.25%. Among the three techniques presented DWT yielded the highest classification accuracy. Thus, the proposed CAD approach may be used as a complementary tool to assist cardiologists in making a more accurate diagnosis for the presence of MI.

  7. The RNA-binding protein HOS5 and serine/arginine-rich proteins RS40 and RS41 participate in miRNA biogenesis in Arabidopsis

    KAUST Repository

    Chen, Tao

    2015-07-30

    MicroRNAs are a class of small regulatory RNAs that are generated from primary miRNA (pri-miRNA) transcripts with a stem-loop structure. Accuracy of the processing of pri-miRNA into mature miRNA in plants can be enhanced by SERRATE (SE) and HYPONASTIC LEAVES 1 (HYL1). HYL1 activity is regulated by the FIERY2 (FRY2)/RNA polymerase II C-terminal domain phosphatase-like 1 (CPL1). Here, we discover that HIGH OSMOTIC STRESS GENE EXPRESSION 5 (HOS5) and two serine/arginine-rich splicing factors RS40 and RS41, previously shown to be involved in pre-mRNA splicing, affect the biogenesis of a subset of miRNA. These proteins are required for correct miRNA strand selection and the maintenance of miRNA levels. FRY2 dephosphorylates HOS5 whose phosphorylation status affects its subnuclear localization. HOS5 and the RS proteins bind both intronless and intron-containing pri-miRNAs. Importantly, all of these splicing-related factors directly interact with both HYL1 and SE in nuclear splicing speckles. Our results indicate that these splicing factors are directly involved in the biogenesis of a group of miRNA.

  8. The RNA-binding protein HOS5 and serine/arginine-rich proteins RS40 and RS41 participate in miRNA biogenesis in Arabidopsis.

    Science.gov (United States)

    Chen, Tao; Cui, Peng; Xiong, Liming

    2015-09-30

    MicroRNAs are a class of small regulatory RNAs that are generated from primary miRNA (pri-miRNA) transcripts with a stem-loop structure. Accuracy of the processing of pri-miRNA into mature miRNA in plants can be enhanced by SERRATE (SE) and HYPONASTIC LEAVES 1 (HYL1). HYL1 activity is regulated by the FIERY2 (FRY2)/RNA polymerase II C-terminal domain phosphatase-like 1 (CPL1). Here, we discover that HIGH OSMOTIC STRESS GENE EXPRESSION 5 (HOS5) and two serine/arginine-rich splicing factors RS40 and RS41, previously shown to be involved in pre-mRNA splicing, affect the biogenesis of a subset of miRNA. These proteins are required for correct miRNA strand selection and the maintenance of miRNA levels. FRY2 dephosphorylates HOS5 whose phosphorylation status affects its subnuclear localization. HOS5 and the RS proteins bind both intronless and intron-containing pri-miRNAs. Importantly, all of these splicing-related factors directly interact with both HYL1 and SE in nuclear splicing speckles. Our results indicate that these splicing factors are directly involved in the biogenesis of a group of miRNA.

  9. Tracking of physical activity, physical fitness and body mass index from childhood to adolescence

    DEFF Research Database (Denmark)

    Kristensen, Peter Lund

    2007-01-01

    Kardiovaskulære sygdomme er blandt de væsentligste dødsårsager i det moderne vestlige samfund. Sygdommene observeres almindeligvis kun hos voksne, men den almene sundhedstilstand og sundhedsadfærd i barndommen anses for at spille en væsentlig rolle i udviklingen af disse sygdomme. Tidligere studier...

  10. Tracking of physical activity, physical fitness and body mass index from childhood to adolescence

    DEFF Research Database (Denmark)

    Kristensen, Peter Lund

    2007-01-01

    Kardiovaskulære sygdomme er blandt de væsentligste dødsårsager i det moderne vestlige samfund. Sygdommene observeres almindeligvis kun hos voksne, men den almene sundhedstilstand og sundhedsadfærd i barndommen anses for at spille en væsentlig rolle i udviklingen af disse sygdomme. Tidligere studi...

  11. Computer-aided diagnosis of psoriasis skin images with HOS, texture and color features: A first comparative study of its kind.

    Science.gov (United States)

    Shrivastava, Vimal K; Londhe, Narendra D; Sonawane, Rajendra S; Suri, Jasjit S

    2016-04-01

    Psoriasis is an autoimmune skin disease with red and scaly plaques on skin and affecting about 125 million people worldwide. Currently, dermatologist use visual and haptic methods for diagnosis the disease severity. This does not help them in stratification and risk assessment of the lesion stage and grade. Further, current methods add complexity during monitoring and follow-up phase. The current diagnostic tools lead to subjectivity in decision making and are unreliable and laborious. This paper presents a first comparative performance study of its kind using principal component analysis (PCA) based CADx system for psoriasis risk stratification and image classification utilizing: (i) 11 higher order spectra (HOS) features, (ii) 60 texture features, and (iii) 86 color feature sets and their seven combinations. Aggregate 540 image samples (270 healthy and 270 diseased) from 30 psoriasis patients of Indian ethnic origin are used in our database. Machine learning using PCA is used for dominant feature selection which is then fed to support vector machine classifier (SVM) to obtain optimized performance. Three different protocols are implemented using three kinds of feature sets. Reliability index of the CADx is computed. Among all feature combinations, the CADx system shows optimal performance of 100% accuracy, 100% sensitivity and specificity, when all three sets of feature are combined. Further, our experimental result with increasing data size shows that all feature combinations yield high reliability index throughout the PCA-cutoffs except color feature set and combination of color and texture feature sets. HOS features are powerful in psoriasis disease classification and stratification. Even though, independently, all three set of features HOS, texture, and color perform competitively, but when combined, the machine learning system performs the best. The system is fully automated, reliable and accurate. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. Overexpression of an Orchid (Dendrobium nobile) SOC1/TM3-Like Ortholog, DnAGL19, in Arabidopsis Regulates HOS1-FT Expression.

    Science.gov (United States)

    Liu, Xiao-Ru; Pan, Ting; Liang, Wei-Qi; Gao, Lan; Wang, Xiao-Jing; Li, Hong-Qing; Liang, Shan

    2016-01-01

    Flowering in the appropriate season is critical for successful reproduction in angiosperms. The orchid species, Dendrobium nobile, requires vernalization to achieve flowering in the spring, but the underlying regulatory network has not been identified to date. The MADS-box transcription factor DnAGL19 was previously identified in a study of low-temperature treated D. nobile buds and was suggested to regulate vernalization-induced flowering. In this study, phylogenetic analysis of DnAGL9 and the MADS-box containing proteins showed that DnAGL19 is phylogenetically closely related to the SOC1-like protein from orchid Dendrobium Chao Parya Smile, DOSOC1. The orchid clade closed to but is not included into the SOC1-1/TM3 clades associated with either eudicots or monocots, suggesting that DnAGL19 is an SOC1-1/TM3-like ortholog. DnAGL19 was found to be highly expressed in pseudobulbs, leaves, roots, and axillary buds but rarely in flowers, and to be substantially upregulated in axillary buds by prolonged low-temperature treatments. Overexpression of DnAGL19 in Arabidopsis thaliana resulted in a small but significantly reduced time to bolting, suggesting that flowering time was slightly accelerated under normal growth conditions. Consistent with this, the A. thaliana APETELA1 (AP1) gene was expressed at an earlier stage in transgenic lines than in wild type plants, while the FLOWERING LOCUS T (FT) gene was suppressed, suggesting that altered regulations on these transcription factors caused the weak promotion of flowering. HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1) was slightly activated under the same conditions, suggesting that the HOS1-FT module may be involved in the DnAGL19-related network. Under vernalization conditions, FT expression was significantly upregulated, whereas HOS1 expression in the transgenic A. thaliana has a level similar to that in wild type. Taken together, these results suggest that DnAGL19 controls the action of the HOS1-FT module

  13. Overexpression of an orchid (Dendrobium nobile SOC1/TM3-like ortholog, DnAGL19, in Arabidopsis regulates HOS1-FT expression

    Directory of Open Access Journals (Sweden)

    Xiao-ru eLiu

    2016-02-01

    Full Text Available Flowering in the appropriate season is critical for successful reproduction in angiosperms. The orchid species, Dendrobium nobile, requires vernalization to achieve flowering in the spring, but the underlying regulatory network has not been identified to date. The MADS-box transcription factor DnAGL19 was previously identified in a study of low-temperature treated D. nobile buds and was suggested to regulate vernalization-induced flowering. In this study, phylogenetic analysis of DnAGL9 and the MADS-box containing proteins showed that DnAGL19 is phylogenetically closely related to the SOC1-like protein from orchid Dendrobium Chao Parya Smile, DOSOC1. The orchid clade closed to but is not included into the SOC1-1/TM3 clades associated with either eudicots or monocots, suggesting that DnAGL19 is an SOC1-1/TM3-like ortholog. DnAGL19 was found to be highly expressed in pseudobulbs, leaves, roots and axillary buds but rarely in flowers, and to be substantially upregulated in axillary buds by prolonged low-temperature treatments. Overexpression of DnAGL19 in Arabidopsis thaliana resulted in a small but significantly reduced time to bolting, suggesting that flowering time was slightly accelerated under normal growth conditions. Consistent with this, the A. thaliana APETELA1 (AP1 gene was expressed at an earlier stage in transgenic lines than in wild type plants, while the FLOWERING LOCUS T (FT gene was suppressed, suggesting that altered regulations on these transcription factors caused the weak promotion of flowering. HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1 was slightly activated under the same conditions, suggesting that the HOS1-FT module may be involved in the DnAGL19-related network. Under vernalization conditions, FT expression was significantly upregulated, whereas HOS1 expression in the transgenic A. thaliana has a level similar to that in wild type. Taken together, these results suggest that DnAGL19 controls the action of the

  14. En handlingsmodell för förebyggandet av psykologiska komplikationer hos kvinnor som genomgår avbrytande av havandeskap

    OpenAIRE

    2014-01-01

    Abstrakt Utvecklingsarbetet ”En handlingsmodell för förebyggandet av psykologiska komplikationer hos kvinnor som genomgår avbrytande av havandeskap”, är en fortsättning på examensarbetet ”Abort - En systematisk översikt av kvinnornas upplevelser och av vårdpersonalens betydelse” som publicerades och presenterades våren 2013. Syftet med utvecklingsarbetet är att producera en handlingsmodell för hälsovårdspersonalen. Handlingsmodellen kommer att ge råd och tips på hur man som hälsovårdspe...

  15. Distriktssköterskans arbete med, och erfarenhet av livsstilsförändringar hos patienter med pre-diabetes : En kvalitativ intervjustudie

    OpenAIRE

    Erlandsson, Emma; Johnson, Marit

    2016-01-01

    Syftet med denna studie var att beskriva distriktssköterskans arbete med, och erfarenhet av livsstilsförändringar hos patienter med pre-diabetes inom primärvården. Metod var en empirisk intervjustudie med en kvalitativ ansats. Åtta semistrukturerade intervjuer utfördes, intervjumaterialet analyserades utifrån Graneheim och Lundmans innehållsanalys. Resultatet visade att patienter med pre-diabetes oftast upptäcktes i samband med årskontrollen hypertoni eller då de sökte för andra besvär. Blods...

  16. Hyperbilirubinemi hos nyfødte – et kontroversielt tema. Erfaringer med nye indikasjoner for fototerapi og utskiftningstransfusjon

    Directory of Open Access Journals (Sweden)

    Alf Meberg

    2009-10-01

    Full Text Available  SAMMENDRAGNye indikasjoner for behandling av hyperbilirubinemi hos nyfødte (bilirubinskjema fra Hillingdon sykehus,England ble innført ved Vestfold sentralsykehus primo 1994. Endringene i panoramaet av behandlingstiltak(lysbehandling, utskiftningstransfusjon ble registrert i kohortene av levende fødte ved sykehuset i toårsperioden1994-95 og sammenlignet med foregående treårsperiode 1991-93. Total lysbehandlingsprevalens falt signifikantfra 6,9% av levende fødte i perioden 1991-93 til 5,5% i perioden 1994-95 (p betydelig fall i prevalensen av fullbårne barn som ble lysbehandlet for fysiologisk ikterus, fra 4,3% til 1,6% ihenholdsvis første og siste periode (p steg signifikant fra 2,0% av levende fødte til 3,2% (p økning i prematuritetsinsidensen, som steg fra 4,5% i perioden 1991-93 til 5,9% i perioden 1994-95 (p Andelen premature som ble lysbehandlet steg fra 45,2% i første til 53,1% i siste periode (p av blodgruppeimmuniserte barn som ble lysbehandlet var uforandret i de to periodene (henholdsvis 0,6% og0,7% (p > 0,05. Det var en markert reduksjon i prevalensen av barn som gjennomgikk utskiftningstransfusjon(fra 0,2 til 0,06% henholdsvis i de to periodene (p effekter av lysbehandling til friske fullbårne barn med ikterus, reduseres relativt betydelig med de moderatejusteringer av indikasjonene som er foretatt. Rutineskiftet har også betydd ressurssparing. På landsbasis vil en slikrutineendring medføre at 1000-2000 fullbårne barn hvert år kan unngå lysbehandling. Indikasjonene for fototerapiog utskiftningstransfusjon for hyperbilirubinemi hos nyfødte i Norge må diskuteres på nytt i lys av ny forskningmed tanke på nasjonal konsensus. Kortere liggetider for nyfødte i sykehus etter fødselen gjør det nødvendig medgode rutiner for oppfølging av hyperbilirubinemi utenfor sykehus.Meberg A. Hyperbilirubinemia – a controversial topic. Experiences with new guidelines for phototherapyand exchange transfusion . Nor J

  17. eSundhedskompetence og brugsmønstre af eksisterende e-sundhedstilbud hos ambulante medicinske patienter med kroniske sygdomme-spørgeskemaundersøgelse

    DEFF Research Database (Denmark)

    Holt, Kamila Beata Adellund

    2016-01-01

    kontrolforløb enten for type 2-diabetes, thyreoidea sygdom eller lever- og inflammatorisk tarmsygdom. De tre sygdomsgrupper rummer forskellige ætiologier og udvikles på grund af arvelighed og/eller livsstil og miljøfaktorer. Stofskiftesygdomme har ofte en autoimmun ætiologi. Leversygdomme og type 2-diabetes er...... patienternes eSundhedskompetence. Dette er ikke undersøgt tidligere. Målingerne af e-Sundhedskompetence hos patienterne er foretaget ved hjælp af validerede spørgeskemaer som er: eHLQ (eHealth Literacy Questionnaire) og eHLA (eHealth Literacy Assessment) suppleret med otte spørgsmål, som afdækker konkret brug...

  18. Analys av Lagerhållningsstrategier för Surfplattor hos en Hemelektronikkedjas Återförsäljare

    OpenAIRE

    Samsioe Guldbrand, Louise; Karaca, Ferhat

    2014-01-01

    Föreliggande examensarbete undersöker möjligheterna att effektivisera order- och lagerhanteringen av surfplattor hos företaget Företag A. Arbetet är avgränsat till företagets varuhus i Barkarby och till de två största märkena på marknaden just nu; Apple och Samsung. Detta är ett ämne som är relativt nytt eftersom det är en relativt ny marknad runt hela världen som har exploderat sedan Apples första lansering av surfplattan. Eftersom Företag A säljer samtliga märkens surfplattor vilka har helt...

  19. Förändring av layout och materialflöde i färdigvarulager hos AnVa Polytech AB

    OpenAIRE

    Andersson, Marcus

    2017-01-01

    Syftet med detta arbete var att ta fram en lösning för en layoutförändring i ett färdigvarulager hos AnVa Polytech AB i Sunne. I den nya layouten skulle även en lösning för ett enordersflöde med hjälp av en rullbana tas fram. I dagsläget arbetade två anställda parallellt med två olika ordrar som skulle skickas till kund. Målet med arbetet var skapa en bättre arbetsmiljö, ett bättre flöde, minimera antalet onödiga transporter samt minska risken för störningar. Genom att genomföra ett antal akt...

  20. Forskning i musikterapi - posttraumatisk stressbelastning (PTSD)

    DEFF Research Database (Denmark)

    Beck, Bolette Daniels; Mumm, Helle

    2015-01-01

    Denne artikel præsenterer videnskabelige undersøgelser af musikterapi med mennesker, der har fået diagnosen PTSD. Der er forskningsmæssig evidens for at musikterapi kan reducere symptomer på posttraumatisk stress hos børn, unge og voksne. Undersøgelser af musikterapi med voksne med posttraumatisk...... musikterapi med børn og unge med indlæringsproblemer som følge af PTSD viser reduktion af hyperaktivitet, aggression og depression samt øget lydhørhed og forbedrede sociale kompetencer....... stress viser reduktion af symptomer som flashbacks, undgåelsesadfærd, stress samt dissociation, depression og angst. Musikterapi med voksne kan endvidere skabe forbedringer i forhold til søvnkvalitet og social kontakt, samt styrke oplevelsen af mening og sammenhæng i tilværelsen. Undersøgelser af...

  1. Botulisme hos et spaedbarn

    DEFF Research Database (Denmark)

    Nielsen, Allan Bybeck; Nordly, Sannie Brit; Clausen, Marianne Engel

    2010-01-01

    investigation, contaminated food was not found. One particular batch of canned baby food was suspected and recalled from the market, but no contamination was found. The girl had not ingested honey. The condition is rare, but can be very serious and should be kept in mind in cases presenting with the well...

  2. Bilateral akillesseneruptur hos nyretransplanterede

    DEFF Research Database (Denmark)

    Skovgaard, D; Feldt-Rasmussen, B F; Nimb, L

    1996-01-01

    Increased incidence of tendinitis and tendon ruptures is reported in recipients of a kidney transplant. Two cases of bilateral achilles tendon rupture after minimal trauma are described. Tendon ruptures are more frequent in individuals with kidney disease in dialysis or after transplantation...... compared with patients receiving other organ transplantations. It is therefore more likely that tendon ruptures are related to metabolic changes associated with kidney disease rather than with transplantation or with glucocorticoid treatment per se. Clinical symptoms of achilles tendinitis should...

  3. Ingen tomgang hos Tiller

    DEFF Research Database (Denmark)

    Munch, Per

    2000-01-01

    Tom Tillers bog 'Forskende partnerskab - aktionsforskning og aktionslæring i skolen' er på mange måder uhyre aktuel i en dansk sammenhæng. Det er den blandt andet, fordi den placerer sig midt i diskussionen om lærernes efter- og videreuddannelse.......Tom Tillers bog 'Forskende partnerskab - aktionsforskning og aktionslæring i skolen' er på mange måder uhyre aktuel i en dansk sammenhæng. Det er den blandt andet, fordi den placerer sig midt i diskussionen om lærernes efter- og videreuddannelse....

  4. Lejringsskader hos rygopererede patienter

    DEFF Research Database (Denmark)

    Sestoft, Bodil; Larsen, Birgit; Erlandsen, Mogens;

    2009-01-01

    INTRODUCTION: The aim of this study was to answer the questions: Which kind of positioning injuries occurred in anaesthetized orthopaedic patients undergoing spine surgery who were prone-positioned for more than two hours? What was the incidence of positioning injuries? Which patients were at par...

  5. Hypertension hos gravide

    DEFF Research Database (Denmark)

    Mathiesen, Elisabeth R; Johansen, Marianne; Kamper, Anne Lise;

    2009-01-01

    There are four major hypertensive disorders in pregnancy: chronic hypertension, gestational hypertension, preeclampsia and chronic hypertension with superimposed preeclampsia. The indications and efficacy of antihypertensive treatment of the different hypertensive disorders are assessed. Advantages...... and disadvantages of different classes of antihypertensive drugs during pregnancy and lactation are described....

  6. Influenzavirus hos svin

    DEFF Research Database (Denmark)

    Dalsgård, Anders; Larsen, Lars Erik

    2009-01-01

    Med fundet af H1N1 virus i en cansdisk svinebesætning har den aktuelle humane, influenzaepidemi fået en veterinærvinkel og er rykket tættere på Danmark, mener ekspert fra DTU Veterinærinstituttet.......Med fundet af H1N1 virus i en cansdisk svinebesætning har den aktuelle humane, influenzaepidemi fået en veterinærvinkel og er rykket tættere på Danmark, mener ekspert fra DTU Veterinærinstituttet....

  7. Pulmonal fedtemboli hos traumepatient

    DEFF Research Database (Denmark)

    Rudolph, Søren F.; Hansen, Nikolaj Friis; Edström, Birgitte

    2007-01-01

    Pulmonal fedt emboli (PFE) kan ses, når fedt perler udskilles fra fedtholdige væv og emboliserer i den pulmonale mikrovaskulære cirkulation. Tilstanden ses ved frakturer, særligt lukkede frakturer af lange rørknogler, pelvis og costae 1, 2, men også ved massive bløddelsskader 3, 4, ortopædkirurgi......Pulmonal fedt emboli (PFE) kan ses, når fedt perler udskilles fra fedtholdige væv og emboliserer i den pulmonale mikrovaskulære cirkulation. Tilstanden ses ved frakturer, særligt lukkede frakturer af lange rørknogler, pelvis og costae 1, 2, men også ved massive bløddelsskader 3, 4......, ortopædkirurgiske indgreb, samt et række medicinske tilstande. Forløbet er variabelt, oftest godartet, med lette lungesymptomer, men kan være fatalt. PFE er en klinisk eksklusions diagnose - der findes ikke parakliniske metoder til at påvise PFE. Symptomerne er uspecifikke og kan ses ved anden kritisk sygdom. PFE...

  8. Harepest hos jaeger

    DEFF Research Database (Denmark)

    Edfors, Robert; Smith, Birgitte; Lillebaek, Troels

    2010-01-01

    "Rabbit fever" (Francisella Tularensis) is a rare infection in Denmark. It was first described in Denmark in 1987. It is most likely to affect people who come into close contact with infected animals or ticks, such as hunters, butchers and veterinarians. The diagnosis should be suspected in such ......"Rabbit fever" (Francisella Tularensis) is a rare infection in Denmark. It was first described in Denmark in 1987. It is most likely to affect people who come into close contact with infected animals or ticks, such as hunters, butchers and veterinarians. The diagnosis should be suspected...

  9. Nogle argumentationsgange hos Habermas

    DEFF Research Database (Denmark)

    Dupont, Søren

    1985-01-01

    Artiklen forholder sig til væsentlige begreber fra Habermas' teori om den kommunikative handlen.......Artiklen forholder sig til væsentlige begreber fra Habermas' teori om den kommunikative handlen....

  10. Dannelse af nye nerveceller i den voksne hjerne

    DEFF Research Database (Denmark)

    Poulsen, Frantz Rom; Meyer, Morten; Rasmussen, Jens Zimmer

    2003-01-01

    neurogenesis in the adult human brain. In particular two brain regions show continuous division of neural stem and progenitor cells generating neurons and glial cells, namely the subgranular zone of the dentate gyrus and the subventricular zones of the lateral ventricles. From the latter region newly generated...... neuroblasts (immature nerve cells) migrate toward the olfactory bulb where they differentiate into neurons. In the dentate gyrus the newly generated neurons become functionally integrated in the granule cell layer, where they are believed to be of importance to learning and memory. It is at present not known...

  11. Personalets deltagelse i forebyggelse blandt voksne patienter i almen laegepraksis

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; K. Rasmussen, Niels; Munck, Anders P

    2008-01-01

    of the doctors stated that the staff performed tasks in connection with weight control, vaccination of adults, blood pressure checks, lung function tests, alcohol abuse treatment and dietary counselling. A total of 72% of the doctors wished for greater staff involvement within one or more areas, especially...

  12. En film for børn og enfoldige voksne

    DEFF Research Database (Denmark)

    Necef, Mehmet Ümit

    2009-01-01

    Artiklen gennemgår en række anmeldelser af filmen Flugten og fremfører, at både filmen selv og de positive anmeldelser er eksempler på infantilisering og enfoldiggø-relse af anti-racismen i Danmark. Udgivelsesdato: Sept 2009...

  13. Unge voksne på Tinder : en kvalitativ studie

    OpenAIRE

    Ottesen, Mathilde Dagsvik

    2015-01-01

    Denne studien undersøker Tinder som arena for selvpresentasjon. Gjennom kvalitative intervjuer med syv studenter mellom 20 og 30 år, har jeg søkt svar på hvordan en presenterer seg selv på Tinder, hvordan en vurderer andre brukeres selvpresentasjon, samt implikasjoner av Tinder. I samsvar med Bourdieu (1986), undersøker jeg Tinder som et sosi...

  14. Paracetamoldosering til børn--anderledes end til voksne

    DEFF Research Database (Denmark)

    Jensen, Kaspar Buus; Dalhoff, Kim P

    2005-01-01

    Paracetamol (acetaminophen) has become the most widely used antipyretic and analgesic drug for children in Denmark. However, there is a wide discrepancy between the consumption of the drug and our knowledge of children's pharmacokinetics and pharmacodynamics. Dosage, therapeutic intervals and toxic...... potential are different for children and adults. In this review we look at the published guidelines for treating children with paracetamol and the evidence supporting them....

  15. Dannelse af nye nerveceller i den voksne hjerne

    DEFF Research Database (Denmark)

    Poulsen, Frantz Rom; Meyer, Morten; Rasmussen, Jens Zimmer

    2003-01-01

    Generation of new nerve cells (neurogenesis) is normally considered to be limited to the fetal and early postnatal period. Thus, damaged nerve cells are not expected to be replaced by generation of new cells. The brain is, however, more plastic than previously assumed. This also includes neurogen......Generation of new nerve cells (neurogenesis) is normally considered to be limited to the fetal and early postnatal period. Thus, damaged nerve cells are not expected to be replaced by generation of new cells. The brain is, however, more plastic than previously assumed. This also includes...... neurogenesis in the adult human brain. In particular two brain regions show continuous division of neural stem and progenitor cells generating neurons and glial cells, namely the subgranular zone of the dentate gyrus and the subventricular zones of the lateral ventricles. From the latter region newly generated...... whether neurogenesis in the adult human brain can be manipulated for specific repair after brain damage....

  16. Roman for unge - og deres voksne - fra Nick Hornby

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2007-01-01

    Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207......Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207...

  17. Basal genoplivning af voksne og automatisk ekstern defibrillering

    DEFF Research Database (Denmark)

    Berlac, P.A.; Lippert, F.K.; Torp-Pedersen, Christian Tobias

    2008-01-01

    The new ERC guidelines on resuscitation emphasize the importance of quality CPR. BLS should be started as early as possible. Lay rescuers should not check for a pulse, they should call for help and start chest compressions immediately. Compression depth should be 4-5 cm at a rate of 100 compressi......The new ERC guidelines on resuscitation emphasize the importance of quality CPR. BLS should be started as early as possible. Lay rescuers should not check for a pulse, they should call for help and start chest compressions immediately. Compression depth should be 4-5 cm at a rate of 100...... compressions per minute. Chest compressions and ventilation should be performed in a ratio of 30:2. Lay rescuers should continue until professional help arrives. Lay rescuers may use the same procedure for children as recommended for adults. Professionals should, however, initiate CPR in children with 5...

  18. Voksnes læring i virtuelle omgivelser

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Lerche

    2005-01-01

    kommunikation, hvor deltagere på samme tid via tekst (som i chat og 'instant messaging') eller via lyd samtaler online (fx via et voice IP system som Skype). Endelig demonstreres mulighederne for at arbejde med portfolio - det være sig løbende arbejdsportfolio eller produkt-præsentationsportfolio, hvor...

  19. Personalets deltagelse i forebyggelse blandt voksne patienter i almen laegepraksis

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; K. Rasmussen, Niels; Munck, Anders P

    2008-01-01

    ) the doctors' wishes for increased involvement. MATERIALS AND METHODS: In total, 378 out of 381 general practitioners from ten counties participating in "Audit on prevention in general practice 2004" filled in a two-page questionnaire. RESULTS: Almost all (377/378) had staff employed. More than half...

  20. Voksnes regnefærdigheder hvordan testes de?

    DEFF Research Database (Denmark)

    Johansen, Lene Østergaard

    2005-01-01

    I sommeren 2000 blev resultaterne af OECD undersøgelsen "Second International Adult Literacy Survey" (SIALS) offentliggjort. Offentliggørelsen medførte et ramaskrig, idet den påviste, at henholdsvis 46% og 28% af den danske befolkningen mellem 16 og 66 år ikke var i besiddelse af tilstrækkelige...... trinopdelte og hvert trin kan afsluttes med en centralt stillet prøve. I mit oplæg vil jeg præsentere, hvorledes deltagerne er blevet testet for regnefærdigheder i SIALS, og hvad de er blevet testet i. Jeg vil sammenligne testen i SIALS med de nye opgavetyper, der er blevet udviklet til FVU-matematik og...

  1. Dömda att leva i skuggan : En kvalitativ intervjustudie om hälsan hos personer med albinism i Rwanda, utifrån begreppen diskriminering, coping och socialt stöd

    OpenAIRE

    Niyonkuru, Elsie Diane

    2016-01-01

    Bakgrund: Oculocutaneous albinism (OCA) är en ärftlig sjukdom som fysiskt, psykiskt och socialt påverkar de drabbade individerna. Okunskap, fördomar och myter om albinism utgör de största orsakerna till den diskriminering som personer med albinism utsatts för särskilt i vissa länder i Afrika söder om Sahara. Syfte: Syftet är att beskriva hälsan hos personer med albinism i Rwanda, utifrån begreppen diskriminering, coping och socialt stöd. Metod: En kvalitativ metod med induktiv ansats ligger t...

  2. Identitetshantering på Facebook : En kvalitativ studie om förhållningssättet till den egna identiteten hos två olika åldersgrupper på vår tids mest offentliga scen

    OpenAIRE

    Kåge, Isabelle

    2010-01-01

    Title: Identity management on Facebook: a qualitative study in approaches to personal identity between two different age groups on the most public stage of our time (Identitetshantering på Facebook: En kvalitativ studie om förhållningssättet till den egna identiteten hos två olika åldersgrupper på vår tids mest offentliga scen). Number of pages: 43. Author: Isabelle Kåge. Tutor: Amelie Hössjer. Course: Media and Communication Studies C. Period: Fall Semester 2010. University: Division of Medi...

  3. Expression and function of the ACE2/angiotensin(1-7)/Mas axis in osteosarcoma cell lines U-2 OS and MNNG-HOS.

    Science.gov (United States)

    Ender, Stephan Albrecht; Dallmer, Andrea; Lässig, Florian; Lendeckel, Uwe; Wolke, Carmen

    2014-08-01

    The renin-angiotensin-system (RAS), via its classical angiotensin-converting enzyme (ACE)/angiotensin II/angiotensin II type 1 receptor (AT1R)-axis, is associated with proliferation and metastasis of numerous types of solid tumor. AT1R blockers reduce tumor volume and decrease liver and lung metastasis in murine models of osteosarcoma. Expression and function of the alternative ACE2/Ang(1-7)/Mas axis in osteosarcoma is yet to be studied. In the present study, the basic and interleukin (IL)-1β-stimulated expression of components of this alternative RAS axis were analyzed and the impact of Mas on proliferation and/or migration of U-2 OS and MNNG-HOS osteosarcoma cells was studied. Quantitative polymerase chain reaction revealed that the two cell lines expressed the Ang(1‑7)-generating peptidases ACE2, neutral endopeptidase 24.11 and prolyl-endopeptidase together with the putative receptor for Ang(1-7), Mas. IL-1β provoked an induction of Mas mRNA and protein expression which was associated with a reduction of proliferation and migration. By contrast, small interfering RNA-mediated knockdown of Mas expression led to increased cell proliferation. In conclusion, osteosarcoma cells express a functional active alternative ACE2/Ang(1-7)/Mas axis. The induction and reinforcement of this axis may be beneficial for the treatment of osteosarcoma by reducing growth and preventing cancer metastasis. These effects may be achieved directly by the administration of Mas agonists or, indirectly, via blocking the classical AngII RAS axis via ACE inhibitors or AT1R antagonists.

  4. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-09-09 to 2010-09-27 in response to the Deepwater Horizon oil spill event (NODC Accession 0069071)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-09-09 to 2010-09-27 in response to the Deepwater...

  5. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-08-13 to 2010-08-22 in response to the Deepwater Horizon oil spill event (NODC Accession 0069069)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-08-13 to 2010-08-22 in response to the Deepwater...

  6. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-08-26 to 2010-09-03 in response to the Deepwater Horizon oil spill event (NODC Accession 0069070)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-08-26 to 2010-09-03 in response to the Deepwater...

  7. Behandling af astma hos gravide

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least...... due to suboptimal adherence with controller therapy and pregnant women's concerns about harmful effects of medication on the fetus. This review provides an update on the safety of asthma medication during pregnancy, based on recent clinical studies and international guidelines....

  8. Dilateret kardiomyopati hos en amfetaminmisbruger

    DEFF Research Database (Denmark)

    Svendsen, Mathias Tiedemann; Lambrechtsen, Jess

    2011-01-01

    The patient presented himself at the primary practitioner with dyspnoea and chest pain, and was initially misdiagnosed as having pneumonia. Two weeks later the patient developed universal oedema and was hospitalized. Echocardiography showed dilated cardiomyopathy. The initial diagnosis was delaye...

  9. Peripartum kardiomyopati hos overvaegtig gravid

    DEFF Research Database (Denmark)

    Kielgast, Urd Lynge; Schierbeck, Louise; Dümcke, Christine;

    2009-01-01

    Peripartum cardiomyopathy (PPCM) is a rare, but life-threatening cardiac disorder which complicates pregnancy. However, the classical symptoms of heart failure can be masked - especially in obese women. Here, we present a case report of PPCM complicated with vitamin-D deficiency in a severely obese...

  10. Diagrammer hos Pierce og Deleuze

    DEFF Research Database (Denmark)

    Busk, Malene

    2006-01-01

    Artiklen omhandler to forskellige begreber om diagrammet, nemlig Pierces og Deleuzes. De definerer udfra to meget forskellige udgangspukter begge diagrammet som kreativt redskab......Artiklen omhandler to forskellige begreber om diagrammet, nemlig Pierces og Deleuzes. De definerer udfra to meget forskellige udgangspukter begge diagrammet som kreativt redskab...

  11. Delirium hos kritisk syge patienter

    DEFF Research Database (Denmark)

    Strøm, Thomas; Pande-Rolfsen, Guri; Hagen, Christine

    2009-01-01

    Interest in and the quantity of publications on delirium in critically ill patients have grown increasingly over the last decade. Critically ill patients have traditionally been sedated to facilitate mechanical ventilation. This practice impeded the recognition of delirium in the critically ill...... patients, and consequently the disorder was underdiagnosed. Delirium in the critically ill patients is associated with increased morbidity and mortality. Less sedation, guided by protocols with daily wake up trials, and validated delirium scoring systems, have improved the opportunities to diagnose...... and monitor delirium in the critically ill patients. Udgivelsesdato: 2009-Oct-19...

  12. Demenslidelser hos aeldre tyrkiske indvandrere

    DEFF Research Database (Denmark)

    Rosenbaum, Bent; Kristensen, Majken; Schmidt, John

    2008-01-01

    The health condition in a population of elderly Turkish immigrants is investigated with special focus on dementia conditions. The possibility to use the screening test Mini Mental State Examination (MMSE) in relation to the investigated population is evaluated as well as their future need...

  13. Delirium hos kritisk syge patienter

    DEFF Research Database (Denmark)

    Strøm, Thomas; Pande-Rolfsen, Guri; Hagen, Christine;

    2009-01-01

    Interest in and the quantity of publications on delirium in critically ill patients have grown increasingly over the last decade. Critically ill patients have traditionally been sedated to facilitate mechanical ventilation. This practice impeded the recognition of delirium in the critically ill...... patients, and consequently the disorder was underdiagnosed. Delirium in the critically ill patients is associated with increased morbidity and mortality. Less sedation, guided by protocols with daily wake up trials, and validated delirium scoring systems, have improved the opportunities to diagnose...... and monitor delirium in the critically ill patients. Udgivelsesdato: 2009-Oct-19...

  14. Etude structurale des sulfotellurures de terres rares ( LS) 2Te 1+ x ( L = Tb, Dy, Ho, Er, Tm et Y). I. Sous-structure de la phase ordonnée de (HoS) 2Te 1,34. Structure de la phase desordonnée de (TbS) 2Te

    Science.gov (United States)

    Ghémard, G.; Etienne, J.; Flahaut, J.

    1982-11-01

    The lanthanide sulfotellurides ( LS) 2Te 1+ x (0 ≤ x < 0.50) show order-disorder phenomena. Above 450°C, they crystallize in a partially disordered structure, orthorhombic with cell parameters a, b, and c close to 4.1, 5.2, and 13.6 Å, respectively. This structure is determined from diffractometer data on a (HoS) 2Te 1.34 crystal ( R = 0.061). It is built up along the c axis from ( L4S) tetrahedra layers, separated by Te planes. Disorder and nonstoichiometry are related to the two vacant Te sites.

  15. Segmentel vending af tyndtarmen til behandling af voksne patienter med korttarms syndrom

    DEFF Research Database (Denmark)

    Burgdorf, Stefan K; Qvist, Niels; Gögenur, Ismail

    2014-01-01

    Short bowel syndrome is the result of extensive surgical resection, inherited defects or loss of functional absorbing intestine. Parenteral nutrition is associated with high economical expenses, increased morbidity and decreased quality of life. Intestinal transplantation is associated with high...... morbidity and mortality rates. Segmental reversal of the small bowel can prolong the transit time in the small bowel and in many cases permanently end parenteral nutrition dependency. Segmental reversal of the small bowel should be integrated in the surgical treatment of adults with short bowel syndrome....

  16. Institutioner og bostøttetilbud for voksne med vidtgående handicap

    DEFF Research Database (Denmark)

    Gottschalk, Georg; Buch Hansen, C.; Nicolajsen, E.

    I de senere år der sket en udvikling af institutioner og bofællesskaber for udviklingshæmmede, sindslidende og fysisk handicappede. Tilsammen dækker tilbuddene hele skalaen fra den meget specialiserede institution til bostøtteformer, hvor de pågældende personer bor spredt i egne lejligheder med e...

  17. Matematikvanskeligheder i inkluderende undervisning for børn, unge og voksne

    DEFF Research Database (Denmark)

    Lindenskov, Lena

    2006-01-01

    Two international trends are presented by some central documents as they constitute important general frames for understanding and coping with students in mathematics difficulty: A trend towards a political focus on math-containing competence for all, which stresses the need to further work...... in research and practice. And a trend towards political and economical interest in inclusive schools, which challenges thinking on normality and organisation and where concept of inclusion need to be given a mathematical dimension. The article suggests a model for conceptualising mathematics difficulties...

  18. Om modultest og benchmarking i undervisningen af voksne udlændinge i Danmark

    DEFF Research Database (Denmark)

    Petersen, Karen Bjerg

    Denne rapport sammenfatter resultater fra studier og indsamlet datamateriale om udvalgte undervisningsaktørers forståelser og holdninger til indførelsen af benchmarkingundersøgelser og high-stakes sprogtest, de såkaldte modultest, der er indført med lov 375 om danskuddannelser i 2003. Resultaterne...... en vis skepsis overfor benchmarkingundersøgelser blandt både ledere og undervisere. Samtidig synes indførelsen af high-stakes modultest ifølge de adspurgte aktører at have fået afgørende og tilsyneladende også uhensigtsmæssig indflydelse på såvel pædagogisk udvikling som på undervisning og...

  19. Självkänsla hos daghemsbarn : En kvalitativ undersökning om hur barnträdgårdslärare bekräftar och stärker barnets självkänsla på daghem

    OpenAIRE

    Fant, Sofia

    2017-01-01

    Syftet med detta examensarbete är att ta reda på hur en barnträdgårdslärare kan stärka och bekräfta barnets självkänsla på daghem. Vilken syn och uppfattning finns det om självkänslan på daghem och hur kan man stödja barnen på bästa sätt när det gäller självkänslan? I detta examensarbete har jag genom litteratur tagit fram vad självkänsla är, men även olika definitioner kring självkänslan och hur miljön runt om kan påverka självkänslan hos barnet. I intervjuerna som blev gjorda framkom ...

  20. Naturligt forekommende oseltamivirresistens hos influenza A

    DEFF Research Database (Denmark)

    Madsen, Laura; Nielsen, Alex; Lundgren, Jens

    2010-01-01

    in the development of resistance. The best prevention strategy remains vaccination of the general population to avoid immunity. Future antiviral treatment calls for knowledge about resistance to existing types of influenza and the availability of all three types of antiviral medication.......During the last two influenza seasons, one of the predominant influenza A types (H1N1) has developed complete resistance to oseltamivir, the primary treatment option. The virus does, however, remain sensitive to zanamavir and amantadine. There is no unequivocal explanation for this slide...

  1. Kronisk hoste hos børn

    DEFF Research Database (Denmark)

    Grarup, Pernille Abildgaard; Pedersen, Juri Lindy

    2015-01-01

    Cough in children is a common problem of various aetiologies. In the presence of specific findings diagnostics may be easy, but often the symptoms are few and unclear. Management involves specific diagnosing and it should be considered if the cough is acute, prolonged or chronic. The diagnosis de...

  2. Hepatitis B hos børn

    DEFF Research Database (Denmark)

    Christensen, Vibeke Brix; Nordly, Sannie Brit; Kjær, Mette

    2014-01-01

    Chronic hepatitis B (HBV) infection is seen in 400 million persons worldwide. HBV is transmitted vertically or horizontally by infected blood and body fluids. An effective vaccine exists. Most children develop a chronic HBV infection if infected early in life. They are often in an immune...

  3. Dermatologiske reaktioner hos patienter i antineoplastisk behandling

    DEFF Research Database (Denmark)

    Prasad, Sumangali Chandra; Vestergaard, Hanne; Bygum, Anette

    2014-01-01

    Every year more than 33,000 Danish patients are treated with traditional chemotherapy or targeted therapy against cancer. Cutaneous side effects to these therapies are common and may contribute significantly to the morbidity, but rarely to the mortality of the patients undergoing these treatments....... We present the most classical types of drug rashes associated with antineoplastic therapy. Haematologists, oncologists and dermatologists should be aware of these reactions and early recognition and management is important for providing optimal care....

  4. Nekrotiserende fasciitis hos børn

    DEFF Research Database (Denmark)

    Jensen, Karsten Gjessing; Kristensen, Kim

    2009-01-01

    Necrotizing fasciitis (NF) is a serious condition with infection of the muscular fascia causing rapidly spreading necrosis. NF rarely affects children, and we here report two paediatric cases of NF. The first developed NF after a joint puncture, the other after surgical extirpation of a lymph node...

  5. Type 2-diabetes hos etniske minoriteter

    DEFF Research Database (Denmark)

    Zander, Mette; Hansen, Caroline Raun; Koefoed, Birgitte Gade

    2012-01-01

    In general, type 2 diabetes is more common among immigrants than among the inhabitants with a Western background. The higher prevalence among ethnic minorities is probably due to a complex correlation between genetic factors, diet, exercise, linguistic and cultural obstacles, low birthweight...... and high catch up weight as well as socio-economic factors. Ethnic minorities are heterogeneous, and individual initiatives within the different groups are needed. The evidence regarding the effect of initiatives targeted at ethnic minorities in Denmark is sparse. In future, clinically controlled studies...

  6. Lupin og cikorie gavner tarmsundhed hos slagtesvin

    DEFF Research Database (Denmark)

    Jensen, Annette Nygaard; Baggesen, Dorte Lau; Mølbak, Lars

    2011-01-01

    Ved at fodre slagtesvin med 25 procent blå lupin i stedet for standard-foder i blot én uge inden slagtning, kan man tilsyneladende reducere antallet af campylobacter i svinenes gødning......Ved at fodre slagtesvin med 25 procent blå lupin i stedet for standard-foder i blot én uge inden slagtning, kan man tilsyneladende reducere antallet af campylobacter i svinenes gødning...

  7. Spiritualitet som coping hos tibetanske torturoverlevere

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Husum, Kristian

    2010-01-01

    symptoms of severe traumatisation (Hopkin's Symptom Checklist), but probably not as extensive as torture survivors from other cultures. CONCLUSION: The Tibetan torture survivors use Tibetan Buddhism as an important coping mechanism. Most clients expressed satisfaction with counselling, but criticised......INTRODUCTION: There is solid documentation for the positive relationship between spirituality and health, but few examples of how this link may be used in projects of rehabilitation after war, civil conflicts and natural disasters. One such example is the Danida funded Tibetan Torture Program...... in India. This study aims to provide evidence of the Tibetan torture survivors' degree of traumatisation and their use of spirituality to overcome their difficult situation. MATERIAL AND METHODS: The study consists of an assessment and a rehabilitation part. A total of 102 Tibetan torture survivors were...

  8. Propanthelinbromid er effektivt mod savlen hos hunde

    DEFF Research Database (Denmark)

    Gyldenløve, Mette; Thyssen, Jacob P

    2015-01-01

    Hyperhidrosis is a common condition characterized by extensive sweat secretion. Systemic treatment with anticholinergics might prove effective, but patients often suffer from side effects, e.g. dryness of the mouth. We present a clinical case of severe polydipsia in a six-month-old puppy who had...

  9. Topos og trope hos Josefine Klougart

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2014-01-01

    Artiklen handler om sted og metafor, topos og trope, i Josefine Klougarts debutroman Stigninger og Fald (2010), med udblik til de to efterfølgende romaner Hallerne (2011) og En af os sover (2012). Det er tesen at de tre romaner har hver deres markante topografi, forstået som strukturen både i de...

  10. The Application of HOS to PLRS

    Science.gov (United States)

    1977-11-01

    necessary, interfaces that were missing in the specification document. We have just completed the definition of a multilanguage structured flowcharter in...Engineer", Digest of Papers, Fall COMPCON 77 (Washington, D.C.), I EE Computer Society , Cat. No. 77CH1258-3C, Sept. 6-9, 1977. L6 J Hamilton, M. and...PaDers, Fall COMPCON 77 (Washington, D.C.), IEEE Computer Society , Cat. No. 77CG1258-3C, Sept. 6-9, 1977. [7] Searle, J.R. "Review of J.M. Sadock, Toward a Linguistic Theory of Speech Acts," Language 52, 1976. 141

  11. Smitteopsporing efter fund af lungetuberkulose hos flyrejsende

    DEFF Research Database (Denmark)

    Lynggaard, Charlotte Duch; Eriksen, Nina Marie Birk; Andersen, Peter Henrik

    2011-01-01

    During international air travel individuals stay in a closed environment which might lead to a risk of transmission of respiratory infectious diseases such as tuberculosis carried by infectious travellers. Tracing exposed passengers requires international cooperation and assistance from relevant...... authorities. We describe an investigation among fellow passengers to a traveller with sputum positive pulmonary tuberculosis....

  12. Muskelstyrken hos patienter med fibromyalgi. Et litteraturstudie

    DEFF Research Database (Denmark)

    Dombernowsky, Tilde; Dreyer, Lene; Bartels, Else Marie

    2008-01-01

    Do patients with fibromyalgia (FM) have reduced muscular strength? We examined 22 articles and conclude from the results of these that FM patients have reduced muscular strength in their hands and quadriceps. The material also suggests generalised reduced muscular strength. However, the studies...

  13. Fritids- og sportsaktiviteter hos yngre pacemakerpatienter

    DEFF Research Database (Denmark)

    Mickley, H; Petersen, J

    1989-01-01

    : Badminton (3), bicycle-riding (6), firefighting (1), fishing (3), golf (2), gymnastics (3), handball (1), hunting (4), riding (1), running/jogging (4), sailing (5), shooting (2), skiing (3), soccer (5), swimming (1), theatre (1), chorus (1), and tennis (2). No significant changes in the levels of activity...

  14. Akut svimmelhed hos den neurologiske patient

    DEFF Research Database (Denmark)

    Bruun, Marie; Højgaard, Joan L. Sunnleyg; Kondziella, Daniel

    2013-01-01

    Acute vertigo of neurological origin may be caused by haemorrhages and tumours in the posterior fossa and, most frequently, by ischaemic infarction in the vertebrobasilar circulation. Urgent diagnosis is necessary to avoid further ischaemic episodes, herniation due to cerebellar oedema and/or fatal...... brainstem infarction. The history should focus on accompanying neurological symptoms. However, vertigo with cerebellar lesions may be monosymptomatic and then bedside evaluation of oculomotor function is the key to correct diagnosis. This paper discusses the pathophysiology, symptomatology and clinical...... evaluation of acute vertigo of neurological origin....

  15. Laparoskopisk splenektomi for hereditaer sfaerocytose hos born

    DEFF Research Database (Denmark)

    Petersen, C.R.; Bulut, O.; Jess, P.

    2008-01-01

    Based on the positive international experience with laparoscopic splenectomy on a large number of patients since 1991, we treated two teenagers with symptomatic hereditary spherocytosis and moderate splenomegaly. Both operations and postoperative courses were uneventful, and the children had...

  16. Demenslidelser hos ældre tyrkiske indvandrere

    DEFF Research Database (Denmark)

    Rosenbaum, B.; Kristensen, M.; Schmidt, J.

    2008-01-01

    need for a nursing home. MATERIAL AND METHODS: With the help of an interpreter, the Turkish population of elderly (> 60 years old) in the municipality of Ishoj was interviewed about educational-, working- and health conditions. In addition to MMSE and semi-structured interviews, the ICD-10 criteria...... of screening was shown to be applicable only with modifications to persons who were illiterates and without any education, and to those 1st-generation immigrants who were to a limited degree integrated as citizens CONCLUSION: The increased incidence of dementia conditions and diabetes type-2 shows the need...... were used in diagnosing dementia conditions. RESULTS: We found an increased frequency of dementia conditions (13,3%) compared to the expected prevalence of 7% in the Danish population. Furthermore, we found an increased frequency of diabetes type-2. The use of MMSE as a guideline instrument...

  17. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    of patients discharged with the diagnostic codes ventricular tachycardia, ventricular fibrillation or premature ventricular contractions with cardiomyopathy as the presumed aetiology. Patients discharged during a period of 6 years and 5 months were included in the study. The patients were characterized...

  18. Primaer psoasabsces hos en ung rask mand

    DEFF Research Database (Denmark)

    Nassehi, Damoun; Galbo, Henrik; Skovsgaard, Flemming

    2008-01-01

    A young male saw his general practitioner because of lower back pain, limpness, nightly sweating, subfebrilia, and weight loss. Further diagnostics showed that he had a primary psoas abscess. Psoas abscesses are categorized as primary and secondary. Primary psoas abscess is a rare disease in Europe...

  19. Intrahepatisk galdesten hos en patient med alkaptonuri

    DEFF Research Database (Denmark)

    Bülow, Charlotte; Rosenberg, Jacob

    2009-01-01

    Alkaptonuria is a rare inherited disease with enzyme deficiency in the protein metabolism. The patients accumulate homogentisic acid which leads to symptoms from various body tissues. We describe a patient with recurrent intrahepatic gallstones probably due to such accumulation, and the successful...

  20. Naturligt forekommende oseltamivirresistens hos influenza A

    DEFF Research Database (Denmark)

    Madsen, Laura; Nielsen, Alex; Lundgren, Jens

    2010-01-01

    During the last two influenza seasons, one of the predominant influenza A types (H1N1) has developed complete resistance to oseltamivir, the primary treatment option. The virus does, however, remain sensitive to zanamavir and amantadine. There is no unequivocal explanation for this slide...... in the development of resistance. The best prevention strategy remains vaccination of the general population to avoid immunity. Future antiviral treatment calls for knowledge about resistance to existing types of influenza and the availability of all three types of antiviral medication....

  1. Hepatitis C hos børn

    DEFF Research Database (Denmark)

    Christensen, Vibeke Brix; Nordly, Sannie Brit; Fischler, Bjørn

    2014-01-01

    Chronic hepatitis C (HCV) infection has a prevalence of 2-3% worldwide. The vertical transmission rate is approximately 5%. There is no evidence to recommend abstinence from breastfeeding or elective C-section to prevent transmission. In children, the natural history of HCV infection is typically...

  2. Naturligt forekommende oseltamivirresistens hos influenza A

    DEFF Research Database (Denmark)

    Madsen, Laura; Nielsen, Alex; Lundgren, Jens

    2010-01-01

    During the last two influenza seasons, one of the predominant influenza A types (H1N1) has developed complete resistance to oseltamivir, the primary treatment option. The virus does, however, remain sensitive to zanamavir and amantadine. There is no unequivocal explanation for this slide...... in the development of resistance. The best prevention strategy remains vaccination of the general population to avoid immunity. Future antiviral treatment calls for knowledge about resistance to existing types of influenza and the availability of all three types of antiviral medication....

  3. Obstetriske komplikationer hos kvinder med endometriose

    DEFF Research Database (Denmark)

    Berlac, Janne Foss; Hartwell, Dorthe; Langhoff-Roos, Jens;

    2014-01-01

    Approximately 5-10% of the women in the reproductive age are afflicted with endometriosis and many become pregnant after fertility treatment. Women with endometriosis seem to have an increased risk of placental complications, bleeding in pregnancy and during labour as well as possible increased r...... risk of pre-eclampsia, preterm birth and low birthweight. Large epidemiological studies are needed to clarify the magnitude of these risks in order to define the appropriate level of proactive management of pregnant women with endometriosis....

  4. Psykologiske reaktioner hos unge vidner til drab

    DEFF Research Database (Denmark)

    Eriksen, Sara Bek

    2013-01-01

    Skeletal stem cells confer to bone its innate capacity for regeneration and repair. Bone regeneration strategies seek to harness and enhance this regenerative capacity for the replacement of tissue damaged or lost through congenital defects, trauma, functional/esthetic problems, and a broad range...... of diseases associated with an increasingly aged population. This review describes the state of the field and current steps to translate and apply skeletal stem cell biology in the clinic and the problems therein. Challenges are described along with key strategies including the isolation and ex vivo expansion...

  5. Addisons sygdom hos femårig

    DEFF Research Database (Denmark)

    Smedegaard, Heidi; Jensen, Rikke Beck; Holm, Kirsten

    2010-01-01

    This case-report presents a 5-year-old girl with gastrointestinal symptoms, who became increasingly confused over the last day before admission. She was believed to be in septic shock or have meningitis and was treated with normal saline infusion, glucocorticoid and antibiotics intravenously. A few...

  6. Svaer metabolisk acidose hos en kronisk alkoholiker

    DEFF Research Database (Denmark)

    Sonne, Morten Egede; Rudolph, Søren Finnemann; Pott, Frank Christian

    2008-01-01

    Severe metabolic acidosis is associated with poor prognosis. We present a patient with profound alcohol and starvation-related combined lactic and keto acidosis (lactate = 29 mM; pH = 6.83) who made a good recovery following 18 hours of intensive care therapy. A brief summary of the proposed...

  7. Erhvervsbetinget eksem hos fynske gartnere og gartnerimedhjaelpere

    DEFF Research Database (Denmark)

    Paulsen, E; Søgaard, J; Andersen, Klaus Ejner

    1998-01-01

    The aims of the study were to assess the prevalence of and association between occupational dermatitis and possible risk factors in gardeners and greenhouse workers living on Funen, describe the distribution of different types of eczema and detect the allergens most commonly involved. A cross-sec...

  8. Diffus lungesygdom hos børn

    DEFF Research Database (Denmark)

    Buchvald, Frederik; Nielsen, Kim G

    2014-01-01

    with a recent paediatric classification have improved our understanding of these disorders. The workup, diagnosis and management of these rare paediatric pulmonary diseases are difficult and require centralised, interdisciplinary team approach in experienced paediatric pulmonary centres....

  9. Mesenteriel thrombangitis obliterans hos en kvinde

    DEFF Research Database (Denmark)

    Laursen, Christian Borbjerg; Knudsen, Anette Hygum; Thorborg, Trine

    2008-01-01

    In this case report we describe a case of meseriental thrombangitis obliterans in a 39-year-old, previously healthy female smoker. She was referred to hospital because of abdominal pains, nausea and diarrhoea. All tests where normal. One year later the patient was admitted due to fever and acute ...

  10. Demens hos personer med Downs syndrom

    DEFF Research Database (Denmark)

    Salem, Lise Cronberg; Jørgensen, Kasper

    2014-01-01

    In developed countries the population of elderly people with Down syndrome expands resulting in an increasing incidence of age-related diseases, including dementia. The assessment of dementia in individuals with intellectual disability is often complicated due to large intra-individual variability...... in cognitive functioning prior to dementia and to lack of standardised measures to detect dementia. Structured observations of symptoms of dementia and assessment techniques tailored for people with intellectual disability are increasingly needed....

  11. Type 2-diabetes hos etniske minoriteter

    DEFF Research Database (Denmark)

    Zander, Mette; Hansen, Caroline Raun; Koefoed, Birgitte Gade;

    2012-01-01

    In general, type 2 diabetes is more common among immigrants than among the inhabitants with a Western background. The higher prevalence among ethnic minorities is probably due to a complex correlation between genetic factors, diet, exercise, linguistic and cultural obstacles, low birthweight and ...

  12. Hodepine hos pasienter som opereres i nakken

    OpenAIRE

    Byhrø, Thomas

    2006-01-01

    Cervicogenic headache (CEH) is a headache by pain starting in the neck radiating forward to the ipsilateral oculo-fronto-temporal area. It can be unilateral or bilateral. The head pain is constant and is often followed by sensory symptoms in the arm on the side of the headache. There can be blurring of vision. Headache is brought on or worsened by movements of neck. There has been much debate on definitions and headache from the neck has many names. The first set of criteria (1) are clinical...

  13. Laryngeal sarkoidose hos 13-årig

    DEFF Research Database (Denmark)

    Herlow, Louise Buchreitz; Rasmussen, Niels

    2010-01-01

    Sarcoidosis is a chronic granulomatous disease of unknown pathogenesis. It can affect numerous organs but most commonly involves the respiratory tract. On rare occasions it only involves the larynx. We describe a case of isolated laryngeal sarcoidosis in a teenage girl with symptoms of hoarseness...

  14. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, A.C.; Sørensen, Helle Christina; Sander, Pia;

    2010-01-01

    INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons. MAT...

  15. Botulisme hos spaedbørn

    DEFF Research Database (Denmark)

    Hoffmann, Thomas; Mølbak, Kåre; Paerregaard, Anders

    2010-01-01

    of voluntary muscles. Presenting symptoms include constipation, lethargy, mydriasis and ptosis. The diagnosis is made on the basis of clinical examination and confirmed by isolating the toxin in serum or stools. Treatment consists of supportive intensive care and treatment with antitoxins....

  16. Kvinnens overflødighet hos Platon

    Directory of Open Access Journals (Sweden)

    Fredrik Nilsen

    2014-11-01

    Full Text Available The Superfluity of Women in Plato. In her article «Plato’s problematic women» Kristin Sampson argues that Plato has two different views on women in the Republic and the Timaeus respectively. In the Republic Plato operates with some sort of equality of status between the two genders, at least in the leaders’ and the soldiers’ classes, whereas in the mythology of the Timaeus women are depicted as reincarnations of men who earlier had lived an unmoral and bad life. According to my interpretation, these two views must be seen as two aspects of one common Greek thought or, as Vigdis Songe-Møller puts it, one common Greek dream, «the dream of the women’s superfluity». In the Republic Plato tries to rule out differences between genders by making the women as similar to men as possible, while in the Timaeus he describes them as something completely different from the norm, the man, and actually as a punishment to men with bad moral behaviour, something that society ideally should do without.

  17. Intervertebral diskitis hos børn

    DEFF Research Database (Denmark)

    Benhassen, Leila Louise; Balslev, Thomas; Gammelgaard, Lise;

    2016-01-01

    Intervertebral discitis is a rare disorder which is easily missed. It presents with non-specific symptoms such as irritability, abdominal pain, decreased appetite and limping. The infection parameters can be normal, and blood cultures are often negative. The pathogenesis is not established...... but infectious, and inflammatory aetiologies have been suggested. Diagnostic golden standard is magnetic resonance imaging. The treatment is immobilization, anti-inflammatory drugs and often antibiotics. Early treatment is important to reduce the risk of complications such as nerve damage and spine fusion....

  18. Cytomegalovirus-colitis hos immunkompetent ung mand

    DEFF Research Database (Denmark)

    Rasmussen, Eva; Grønbaek, Karin; Linnemann, Dorte

    2009-01-01

    haematochezia remained present after six months. Development of IBD subsequent to CMV colitis has previously been described, and is now suspected in our patient. CMV colitis is a rare but possible differential diagnosis in immunocompetent patients with fever, elevated liver enzymes and bloody stools......A healthy young man was hospitalized due to fever, malaise and bloody stools for three weeks. The patient had a primary CMV infection based on biochemical, serological and ultrasonic results, and a colonoscopy was consistent with left-sided CMV colitis. He recovered spontaneously, though...

  19. Kryptorkisme hos drenge med anal atresi

    DEFF Research Database (Denmark)

    Cortes, Dina; Thorup, J M; Nielsen, Ole Henrik;

    1996-01-01

    was the incidence of cryptorchidism. The incidence of renal and ureteric malformations and dysplasias showed a parallel tendency. The incidence of vertebral malformations and dysplasias in the T10-S5 area was low among patients with a covered anus or a perineal fistula. Cryptorchidism was found to be associated...

  20. Abort hos får

    DEFF Research Database (Denmark)

    Agerholm, Jørgen Steen; Fog-Larsen, Anne Marie; Jensen, Tim K.

    2006-01-01

    Forårsages ofte af mikroorganismer, der naturligt forekommer i dyrenes miljø! For at undgå smitte til andre drægtige får bør aborterede fostre og efterbyrden straks fjernes fra folden og moderfåret isoleres....

  1. Botulisme hos spaedbørn

    DEFF Research Database (Denmark)

    Hoffmann, Thomas; Mølbak, Kåre; Paerregaard, Anders

    2010-01-01

    of voluntary muscles. Presenting symptoms include constipation, lethargy, mydriasis and ptosis. The diagnosis is made on the basis of clinical examination and confirmed by isolating the toxin in serum or stools. Treatment consists of supportive intensive care and treatment with antitoxins....

  2. Mundhulens mikroflora hos patienter med marginal parodontitis

    DEFF Research Database (Denmark)

    Larsen, Tove; Fiehn, Nils-Erik

    2011-01-01

    Viden om marginal parodontitis’ mikrobiologi tog for alvor fart for ca. 40 år siden. Den tidlige viden var baseret på mikroskopiske og dyrkningsmæssige undersøgelser af den subgingivale plak. Anvendelsen af de nyere molekylærbiologiske metoder har betydet, at vor viden om de ætiologiske faktorer...

  3. Fritids- og sportsaktiviteter hos yngre pacemakerpatienter

    DEFF Research Database (Denmark)

    Mickley, H; Petersen, J

    1989-01-01

    : Badminton (3), bicycle-riding (6), firefighting (1), fishing (3), golf (2), gymnastics (3), handball (1), hunting (4), riding (1), running/jogging (4), sailing (5), shooting (2), skiing (3), soccer (5), swimming (1), theatre (1), chorus (1), and tennis (2). No significant changes in the levels of activity...

  4. Seksuel funktion hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E; Stenager, E N; Jensen, Knud

    1997-01-01

    Sexual dysfunction is known to occur in multiple sclerosis (MS). The purpose of the study is to describe the change in sexual function and symptoms in a five year follow-up study. Forty-nine patients (27 females, 22 males) with definite MS were interviewed and examined. The number of patients...

  5. Utopi og rejse hos Jens Baggesen

    DEFF Research Database (Denmark)

    Sandberg, A.

    2007-01-01

    En analyse af, hvordan det kosmopolitiske oplysningsideal ændrer sig fra Jens Baggesens dansksprogede rejseskildring Labyrinten til hans tysksprogede epos Oceania i lyset af den begyndende nationalisme. Udgivelsesdato: Jahrgang 28......En analyse af, hvordan det kosmopolitiske oplysningsideal ændrer sig fra Jens Baggesens dansksprogede rejseskildring Labyrinten til hans tysksprogede epos Oceania i lyset af den begyndende nationalisme. Udgivelsesdato: Jahrgang 28...

  6. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...... treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly...

  7. Propofolinfusionssyndromet hos børn

    DEFF Research Database (Denmark)

    Hansen, Tom G

    2005-01-01

    metabolism, resulting in an imbalance between energy demand and utilisation and thus compromising cardiac and peripheral muscle cell function. Propofol should be used with caution for sedation in critically ill children, as well as for long-term anaesthesia in otherwise healthy children, and doses exceeding...

  8. Komplikationer hos gravide med polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Tolstrup, Johan; Jónsdóttir, Fjóla; Ring, Charlotte Mumm;

    2016-01-01

    Pregnant women with polycystic ovary syndrome (PCOS) are at increased risk of pregnancy-related disorders such as gestational diabetes (GDM), gestational hypertension and preeclampsia in the 2nd and 3rd trimester. In addition, the risk of preterm birth, children who are small and large for gestat...... for gestational age, caesarean section and poorer neonatal outcome seem to be elevated, however with less clear evidence. Except for the screening for GDM, there is no evidence of a benefit of increased surveillance during pregnancy for women with PCOS....

  9. Ulnarisneuropati hos fjerkræslagteriarbejder

    DEFF Research Database (Denmark)

    Svendsen, Susanne Wulff; Juhl, Anne

    2008-01-01

    -25 kg with flexion of the elbow, pronation of the forearm, and ulnar deviation of the wrist. A nerve conduction study indicated ulnar neuropathy just distal to the elbow. Surgery at this level alleviated the symptoms, but shortly after his return to work, he changed jobs because of aggravation...

  10. Konstruktionsforberedelse hos Kværner

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Radmer, Jim

    1997-01-01

    Konstruktionsforberedelse kan parallelt til produktionsforberedelse opfattes som opbygning af beredskab og "iscenesættelse" før det egentlige konstruktionsarbejde gennemføres. Der eksisterer allerede i praksis mange måder til opnåelse af større konstruktionsforberedelsesgrad. Toyota anvender...

  11. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    INTRODUCTION: The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet. MATERIALS AND METHODS: The study was a retrospective review......), 57 (45%) patients had arrhythmogenic right ventricular cardiomyopathy (ARVC) and 13 (10%) had hypertrophic cardiomyopathy (HCM). The average age was 44 years for HCM, 41 years for ARVC and 58 years for DCM. The majority of the patients were male. ICD treatment was used in 95% of the patients...

  12. Odontogent myksom i maksillen hos et barn

    DEFF Research Database (Denmark)

    Danielsson, Lina Isabella; Jakobsen, John; Thygesen, Torben H;

    2014-01-01

    exclusively in the maxilla. Orbital involvement is very rare, and to our knowledge reconstruction with a Medpore sheet has not previously been reported. At post-operative follow-up normal eye function and an excellent cosmetic result was observed. OM should be considered in a midfacial mass....

  13. Forekomst af parodontitis og FORL hos perserkatte

    DEFF Research Database (Denmark)

    Flørnæs, Maria L. Topholm; Lund, Mette; Kortegaard, Hanne Ellen;

    2007-01-01

    I dette studie er omfanget af tandrelaterede sygdomme heriblandt parodontitis og feline odontoklastiske resorptions læsioner (FORL) blandt 19 perserkatte (heraf 2 exotics) på 3 til 9 år undersøgt både klinisk og radiografisk. Ingen af kattene havde tidligere fået renset tænder i anæstesi. Alle...... katte havde gingivitis (blødning ved sondering) på mindst en tand. Alle katte havde klinisk parodontitis på mindst 4 tænder, og det sås oftest i kindtænder. 26& havde svær klinisk parodontitis med klinisk fæstetab > 3 mm. Der sås tendens til højere forekomst af svær klinisk parodontitis med stigende...... alder, og den yngste kat i undersøgelsen med svær klinisk parodontitis var 4 år. Prævalensen for parodontitis vurderet radiologisk (alveolært knogletab) fandtes til 58%, og den yngste kat i undersøgelsen med alveolært knogletab var 3 år. Prævalensen for FORL var 47%, og der sås signifikant flere...

  14. Erhvervsbetinget eksem hos fynske gartnere og gartnerimedhjaelpere

    DEFF Research Database (Denmark)

    Paulsen, E; Søgaard, J; Andersen, Klaus Ejner

    1998-01-01

    The aims of the study were to assess the prevalence of and association between occupational dermatitis and possible risk factors in gardeners and greenhouse workers living on Funen, describe the distribution of different types of eczema and detect the allergens most commonly involved. A cross....... Allergic occupational contact dermatitis was suspected in 43 persons (17%). Irritant eczemas outnumbered allergic eczemas and both were most often caused by plants. The lifetime prevalence of occupational dermatitis was 19.6%. Occupational mucosal symptoms, working with Compositae and training...

  15. Problemer med primakin-recidivprofylakse hos malariapatienter

    DEFF Research Database (Denmark)

    Rønn, A M; Bygbjerg, Ib Christian

    1993-01-01

    Standard treatment of P. ovale and P. vivax malaria is 1500 mg of chloroquine base given over three days followed by 15 mg of primaquine base daily for 14 days. At the Department of Infectious Diseases, Rigshospitalet, Copenhagen an increasing number of cases of relative by primaquine-resistant m......Standard treatment of P. ovale and P. vivax malaria is 1500 mg of chloroquine base given over three days followed by 15 mg of primaquine base daily for 14 days. At the Department of Infectious Diseases, Rigshospitalet, Copenhagen an increasing number of cases of relative by primaquine...

  16. Autoinflammatoriske knoglesygdomme hos børn

    DEFF Research Database (Denmark)

    Bech, Agnes Ziobrowska; Herlin, Troels

    2014-01-01

    Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory disease with unpredictable, painful courses of osteolytic lesions in the bones. CNO is frequently associated with psoriasis and inflammatory bowel disease. In cases with multifocal lesions the term chronic recurrent multifocal osteo...... osteomyelitis (CRMO) is preferably used. SAPHO (synovitis, acne, pustulosis palmoplantaris, hyperostosis and osteitis) syndrome is regarded as CRMO in adults. New knowledge of the hereditary forms like Majeed syndrome, deficiency of IL-1-receptor antagonist and cherubism is described....

  17. Eosinofil cystitis hos børn

    DEFF Research Database (Denmark)

    Kvist, Peter Kolja; Cortes, Dina; Visfeldt, J

    1999-01-01

    Eosinophilic cystitis is an inflammatory disorder of the urinary bladder, characterised by irritative voiding symptoms, negative urine cultures, and eosinophilic infiltration of the bladder wall. Since 1960 only about 20 cases have been described in the English scientific reports, making it a rat......Eosinophilic cystitis is an inflammatory disorder of the urinary bladder, characterised by irritative voiding symptoms, negative urine cultures, and eosinophilic infiltration of the bladder wall. Since 1960 only about 20 cases have been described in the English scientific reports, making...... it a rather rare entity. In children the disease appears to be shortlived and self-limited, requiring no specific treatment. We present a case with a 7.5-year-old boy, who experienced spontaneous remission of all symptoms, following an acute attack of eosinophilic cystitis....

  18. Lungeinfektioner er hyppige hos ældre

    DEFF Research Database (Denmark)

    Laut, Kamilla Grønborg; Benfield, Thomas

    2013-01-01

    There are over 20,000 hospital admissions for pneumonia annually in Denmark. The incidence of pneumonia increases with age, functional impairment and co-morbidity. In fact, 60% of admissions occur among persons 65 years or older. The public health burden is expected to increase because this popul......, smoking cessation, mobilization and oral hygiene....

  19. Sundhedsloven og sundhedsydelser hos udokumenterede migranter

    DEFF Research Database (Denmark)

    Aabenhus, Rune Munck; Hallas, Peter

    2012-01-01

    Health-care workers may experience uncertainty regarding legal matters when attending to medical needs of undocumented migrants. This paper applies a pragmatic focus when addressing the legal aspects involved in providing health-care services to undocumented migrants with examples from the Danish...... Health Act and international conventions. The delivery of medical care to vulnerable groups such as pregnant women and children is described....

  20. Durability of shrink joints; Bestaendighet hos krympskarvar

    Energy Technology Data Exchange (ETDEWEB)

    Forsaeus Nilsson, Stefan; Saellberg, Sven-Erik

    2007-07-01

    About one third of all joint failures are caused by shrink seals losing adhesion, according to statistics from the Swedish District Heating Association. The present project was initiated upon request from the Authorisation Board of the Swedish District Heating Association in order to investigate the potential to enhance the quality of shrink joints. The purpose has been to provide a screening of the key properties of the joint systems currently available on the market. The aim has been to facilitate the choice of right materials and constructions to achieve the best functionality and cost effectiveness. The project has comprised a compilation of the views from industry representatives from manufacturers of shrink and sealing materials, pipe producers, joint contractors and district heating companies, and an experimental study where a number of joints were evaluated with respect to tightness and strength. The following joint systems took part in the investigation: Logstor SX; Canusa SuperCase; Raychem RayJoint; Powerpipe DTK with external seal Nitto NeoCover 1150 in one end and Raychem TPSM in the other; Logstor B2S med external seal Canusa KLD in one end and Raychem TPSM in the other. The joints were installed on pipes of diameters 160 mm and 450 mm. The installation was done under cold and dirty conditions, to simulate a field like worst-case scenario. After the installation, the joints were tested with respect to tightness. Peel strength and shear strength were evaluated before and after thermal ageing in +50 deg C for 70 days. Mechanical tests and ageing followed standardised procedure in EN 12068. A study of the shrink force relaxation in crosslinked and non-crosslinked polyethylene shrink sleeves was undertaken, by shrinking them onto aluminium cylinders and storing them in room temperature for about 2000 hours. The results show that it is clearly possible to install excellent shrink joints also under difficult conditions. In addition, thermal ageing does not automatically lead to any dramatic changes in material properties. Of the tested variants, all but one was completely tight and the mechanical strength levels were in line with what the manufacturers state in their data sheets for most of the joints. The measured shrink forces show that relaxation is not a big problem. The material in the joint sleeve will continue to strive towards it non-expanded state of equilibrium, and for the non-crosslinked samples, this actually resulted in an increase in shrink force over time. Since the materials and constructions do work, one may indirectly conclude that the problems are mainly caused by the installation, which, in turn, is likely to a large extent a consequence of difficult working conditions and demanding installation procedures. According to experience, the sealing materials are decisive for the ease of installation. From the fitter's point of view, the sealing material should be soft (more forgiving) and fibre reinforced (easier to handle) and it should come in wide strips (easier to apply). When it comes to sleeves, the shrinking work is faster with crosslinked material (PEX). An important observation is also that sleeves with built-in sealant and/or adhesive are harder to keep clean at the work site. Hence, the most important thing is that the installation is done in a proper manner and that appropriate conditions for the fitter to achieve this is provided at the work site. It is hard to single out the best or the worst joint system, but some recommendations may be given: Remember to depressurise the joint during shrinking to avoid unnecessary pressure loads on the seal. Use a sleeve of crosslinked polyethylene if a fast installation is important. If non-crosslinked sleeves are used, choose a double expanded variant. Use a sealing material with easy handling and forgiving characteristics, e.g., the type used for Nitto NeoCover or Raychem TPSM. If extra strength is needed, use a stronger sealant, such as, e.g., a mastic/hotmelt mix such as that used in Canusa KLD. Please note, though, that high strength does not automatically imply good tightness

  1. Funktion af neoblaere hos kvinder efter cystektomi

    DEFF Research Database (Denmark)

    Bigum, Lene Hyldgaard; Jensen, Jørgen Bjerggaard; Jensen, Klaus Møller-Ernst

    2008-01-01

    complications. Six patients (30%) had late complications. The most common complication was pyelonephritis. Fifteen patients (75%) were alive at the end of follow-up, and twelve patients (60%) were without recurrence. CONCLUSION: Neobladders in women after cystectomy function adequately. Patients achieve a high...

  2. Supervision som undervisningsform i voksenspecialundervisningen

    DEFF Research Database (Denmark)

    Kristensen, René

    2000-01-01

    Supervision som undervisningsform i voksenspecialundervisningen. Procesarbejde i undervisning af voksne.......Supervision som undervisningsform i voksenspecialundervisningen. Procesarbejde i undervisning af voksne....

  3. New osmium cluster compounds containing the heterocyclic ligand 2,3-bis-(diphenylphosphino)quinoxaline (dppq): Ligand isomerization and crystal structures of dppq, the isomeric clusters Os3(CO)10(dppq), and HOs3(CO)9[ -2,3-PhP(h1-C6H4)(Ph2P)quinoxaline

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, Sean W [University of North Texas; Yang, Li [University of North Texas; Wang, Xiaoping [ORNL; Richmond, Michael G. [University of North Texas

    2011-01-01

    Treatment of the labile cluster 1,2-Os{sub 3}(CO){sub 10}(MeCN){sub 2} (1) with the diphosphine ligand 2,3-bis(diphenylphosphino)quinoxaline (dppq) at room temperature affords 1,2-Os{sub 3}(CO){sub 10}(dppq) (2b) as the kinetic product of ligand substitution in 84% yield. 2b isomerizes to the thermodynamically more stable dppq-chelated cluster 1,1-Os{sub 3}(CO){sub 10}(dppq) (2c) as the sole observable product under CO at temperatures below 358 K. The kinetics for the conversion of 2b {yields} 2c have been investigated by NMR spectroscopy in CDCl{sub 3} over the temperature range 323-353 K, and the reaction was found to exhibit a rate law that is first order in 2b. The calculated activation parameters [{Delta}H{sup {ne}} = 25.4(4) kcal/mol; {Delta}S{sup {ne}} = -3(1) eu] support an intramolecular isomerization scenario, one that involves the migration of phosphine and CO groups about the cluster polyhedron. The disposition of the dppq ligand in the isomeric Os{sub 3}(CO){sub 10}(dppq) clusters has been established by X-ray crystallography and {sup 31}P NMR spectroscopy. Photolysis of 2c at 366 nm leads to CO loss and ortho metalation of one of the aryl groups on the Ph{sub 2}P moiety to furnish the hydride cluster HOs{sub 3}(CO){sub 9}[{mu}-PhP({eta}{sup 1}-C{sub 6}H{sub 4})(Ph{sub 2}P)quinoxaline] (3). The isomerization behavior exhibited by 2b follows that of related diphosphine-substituted Os{sub 3} clusters prepared by us.

  4. Udbredelse og opfattelse af angst for tandbehandling blandt voksne danskere.[Prevalence and perceptions of dental anxiety among Danish adults.

    DEFF Research Database (Denmark)

    Moore, Rod; Birn, H.; Brødsgaard, I.

    1993-01-01

    English summary: This telephone survey showed that 4.2% of Danish adults over 16 years old have extreme dental anxiety and 6% have moderate fear in a sample of 565 adults from Århus (Table 1). Common perceptions as to the causes of dental fear indicated that most believed it to be due to pain......, especially from drilling and thereafter trauma or negative experiences leading to distrust of the dentist (Table 1). It was interesting to note that although up to 40% of the sample expressed some degree of fear for dentistry, 81.1% said that they know of at least two persons who have dental fear (16.2% know...... anxiety by the Dental Anxiety Scale (DAS) indicated significant associations between high dental anxiety and gender (women) (Table 2) and low education (Table 3), but not income or age (Table 2). Other significant relationships with high dental fear were fear of specific dental procedures, negative...

  5. Angst for tandbehandling. Prevalens og karakteristika blandt voksne danskere [Fear of dental treatment. Prevalence and characteristics among adult Danes

    DEFF Research Database (Denmark)

    Moore, R.; Brødsgaard, I.; Scheutz, F.

    1995-01-01

    A telephone survey using random sample of residents of the municipality of Aarhus were interviewed about dental treatment fear and characteristics of any pre-existing anxiety. Results showed that 4.2% of 539 residents surveyed had extreme anxiety and 6% were moderately afraid. Results of dental...... anxiety, especially in the odontophobiia group, were years of avoidance of treatment and associated poor subjective perceptions of oral health. Logistic analyses revealed that although dental drilling was the identifying feature of dental anxiety characteristics, the drill could be symbolic for the many...... persons who perceived dentists as treating them with putdowns, angry comments and hardhandedness. Other persons suffered from multiple fears, which may have an accumulative effect on dental treatment anxiety. A conceptual model is presented as derived from present results and existing clinical...

  6. Forekomsten af forkøleslse, snue og hoste blandt voksne danskere. Epidemiologi belyst ved DIKE's befolkningsundersøgelser

    DEFF Research Database (Denmark)

    Trier, H; Rasmussen, N K; Brønnum-Hansen, Henrik

    1991-01-01

    of CC was not associated with occupational exposure, psychological stress, spare time physical activity or smoking habits. Using bivariate analysis, it was shown that exposure to external health risks in the home was reported more frequently among women than men. The results indicate, that exposure...

  7. Udbredelse og opfattelse af angst for tandbehandling blandt voksne danskere.[Prevalence and perceptions of dental anxiety among Danish adults.

    DEFF Research Database (Denmark)

    Moore, Rod; Birn, H.; Brødsgaard, I.

    1993-01-01

    English summary: This telephone survey showed that 4.2% of Danish adults over 16 years old have extreme dental anxiety and 6% have moderate fear in a sample of 565 adults from Århus (Table 1). Common perceptions as to the causes of dental fear indicated that most believed it to be due to pain...

  8. Skandinaviske retningslinjer for akutt håndtering av voksne pasienter med minimal, lett eller moderat hodeskade

    DEFF Research Database (Denmark)

    Sundstrøm, Terje; Wester, Knut; Enger, Martine

    2013-01-01

    BACKGROUND In 2000, the Scandinavian Neurotrauma Committee (SNC) published evidence-based guidelines for the management of minimal, mild or moderate head injuries. Since then, considerable new evidence has emerged on the clinical use of these guidelines and on the radiation risks associated with ...

  9. Nyre- og urinvejsabnormiteter hos småbørn

    DEFF Research Database (Denmark)

    Cortes, Dina; Lee, Kirsten; Thorup, J M

    1999-01-01

    The purpose of this study was to investigate frequency and pattern of urological abnormalities in children younger than two years of age in the county of Frederiksborg, Denmark, with a catchment area of about 350,000 people, and furthermore to investigate in which way the urological abnormalities...... abnormalities after presentry with their first urinary tract infection. The obstructive urological diagnoses: congenital hydronephrosis, congenital megaureter and posterior urethral valves made up to 57% (20/35) of the abnormalities. Nine boys were operated upon; three for unilateral hydronephrosis, two...... for posterior urethral valves, one for unilateral megaureter and three for phimosis. Two girls were treated with oestrogen for labial fusion. Urological abnormalities which were treated were found among the ultrasonographically diagnosed abnormalities, apart from phimosis and labial fusion. The frequency...

  10. Selvstyring af peroral antikoagulationsbehandling hos patienter med kunstige hjerteklapper

    DEFF Research Database (Denmark)

    Hasenkam, J. Michael; Kimose, H H; Grønnesby, H;

    1998-01-01

    Twenty-one heart valve operated patients (age 19-70 years) were trained in self-managed oral anticoagulant therapy using a home coagulometer (CoaguChek). Twenty patients accomplished between eight and 29 (median 24) months of self management and were fully capable of self management after 30 weeks....... All self-managing patients had their median INR-value within the therapeutic range, versus only 14 in the control group. Self-management of oral anticoagulant therapy seems feasible for selected patients. Udgivelsesdato: 1998-Nov-16...... of training. No patients experienced major bleeds or thrombo-embolic events. A control group of 20 patients from our department was matched, retrospectively, to the study group. The self-managing patients were within the therapeutic INR range 78% of the study period compared to 54% for the control patients...

  11. Lönsamhet med CSR hosMAX Hamburgare

    OpenAIRE

    Nisell, Samuel; Kaya, Roni

    2012-01-01

    När företag engagerar sig i CSR-frågor främjar det miljö och samhälle. Denna rapport utreder hur CSR-arbetet också kan gynna företaget ur ett ekonomiskt perspektiv. Rapporten behandlar hamburgerkedjan Max Hamburgares hållbarhetssatsning och besvarar frågorna: • Är Max Hamburgares CSR-arbete ekonomiskt lönsamt för dem själva? • Är någon/några av Max Hamburgares CSR-åtgärder förlust- respektive vinstaffärer? För att besvara frågorna har en omfattande studie kring ämnet och företaget genomförts ...

  12. Parvovirus B19-akut hepatitis hos immunkompetent patient

    DEFF Research Database (Denmark)

    Larsen, Lykke

    2011-01-01

    This article describes a case of acute hepatitis in an adult person without subsequent complications caused by parvovirus B19 (PVB19). The diagnosis was made by detection of PVB19 IgM and IgG antibody in the blood using ELISA. There was not made any affirmative polymerase chain reaction for DNA...

  13. Autenticitet og kritisk sprogfællesskab hos Charles Taylor

    DEFF Research Database (Denmark)

    Crone, Manni

    2002-01-01

    Lever vi i individualistiske samfund, hvor autenticitet og selvrealisering er blevet de højeste værdier? Den canadiske kommunitarist Charles Taylor argumenterer for, at selv om autenticitet og selvrealisering er vigtige værdier for det moderne menneske, kan en excessiv individualisme alligevel...

  14. Body image hos mastektomiopererede kvinder, med og uden rekonstruktion

    DEFF Research Database (Denmark)

    Thorup, Charlotte Brun; Gregersen, Anette Møller; Damgaard, Helle;

    2012-01-01

    Baggrund: I Danmark er incidensen for brystkræft ca. 5.000 årligt. Kvinder, der er mastektomiopereret, risikerer ubalance i body image. De kan føle sig amputeret, lemlæstede, mindre kvindelige og mindre seksuelt attraktive. De kan frygte at se sig selv i spejlet. De kan opleve, at kroppen ikke er...... hel. Mange undersøgelser er kvantitative og kun få har undersøgt kvindernes oplevelse af body image kvalitativt. Formål: At opnå indsigt i danske mastektomiopererede kvinders oplevelse af body image, med fokus på den akutte fase samt år efter operationen, hvor beslutningen om valg eller fravalg af...... rekonstruktion var taget. Metode: Undersøgelsen var fænomenologisk hermeneutisk, idet hensigten var at opnå indsigt i kvinders oplevelser af body image relateret til mastektomi. Fund: Undersøgelsen resulterede i tre temaer, der følger Bob Price begreber. Kropsrealiteten viste sig som ”en krop, der ikke var hel...

  15. Selvadministreret ventrikelsondeernaering hos et barn med infantil autisme

    DEFF Research Database (Denmark)

    Dyrborg, J

    1991-01-01

    An example of self-administered gastric tube nutrition in a boy aged 15 years with infantile autism is presented. The boy would neither eat nor drink in the normal manner since the age of eight years and has gradually administered tube-feeding himself. This patient does not fulfill...

  16. Forbedret overlevelse hos børn med neuroblastom

    DEFF Research Database (Denmark)

    Schrøder, Henrik; Wacher, Jeanette; Larsson, Heidi;

    2010-01-01

    children below 15 years of age with neuroblastoma or ganglioneuroblastoma who were diagnosed in Denmark between 1981 and 2005. RESULTS: The incidence was 8.68 per million children below 15 years of age (world standard 9.6) and 43.5 per million children below 12 months of age and these incidences have...... three years from diagnosis occurred in only 2% of patients. The median time from relapse to death was three months. CONCLUSION: The survival of children with neuroblastoma in Denmark has increased significantly over the last 25 years. Udgivelsesdato: 2010-Oct-4...

  17. Traumatisk distal humerus-epifysiolyse hos nyfødt

    DEFF Research Database (Denmark)

    Al-Aubaidi, Zaid; Nielsen, Keld Daubjerg

    2010-01-01

    Traumatic distal humerus epiphysiolysis (TDHE) is a rare injury in infants with an incidence of about 1:35,000 births. It is primarily a birth injury, but it is also seen in cases of battered child syndrome. Because of its rare occurrence and the diagnostic difficulties, the lesion may be overloo......Traumatic distal humerus epiphysiolysis (TDHE) is a rare injury in infants with an incidence of about 1:35,000 births. It is primarily a birth injury, but it is also seen in cases of battered child syndrome. Because of its rare occurrence and the diagnostic difficulties, the lesion may...

  18. Infektionsrisikoen hos internationale adoptivbørn er reel

    DEFF Research Database (Denmark)

    Pedersen, Tine Marie; Poulsen, Anja; Pedersen, Freddy Karup

    2013-01-01

    -27% have gastrointestinal parasites and 1-7% have tuberculosis, but 3-21% have a positive Mantoux test. The studies found none with HIV or HCV and only a few with syphilis. The vaccination status was often deficient and the serology results did not match the vaccination records. All studies conclude...

  19. Risikofaktorer for selvmord hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E N; Koch-Henriksen, N J; Stenager, E

    1997-01-01

    The purpose of the present study was to describe risk factors for suicide in patients with multiple sclerosis (MS). The study is based on available information about MS-patients identified in the Danish MS Registry with onset of disease in the period 1950-1985. In order to characterize MS suicides...... with respect to risk factors comparisons were made for male and female suicides, and for various groups of MS suicides according to disability status. The male suicides were characterized by a tendency to commit suicide in the age interval 40-49 years, the use of a violent method, previous suicidal behaviour...

  20. Nydiagnosticeret kongenit transposition hos en 76-årig kvinde

    DEFF Research Database (Denmark)

    Sloth, Astrid Drivsholm; Jensen, Jesper Khedri; Hald Steffensen, Flemming

    2009-01-01

    A case of congenitally corrected transposition presenting for the first time with second-degree AV block in a 76-year-old woman is presented. This case demonstrates that congenitally corrected transposition can remain asymptomatic and undiagnosed, especially when no other cardiac defects are pres...

  1. Steatocystoma multiplex hos 39-årig kvinde

    DEFF Research Database (Denmark)

    Duffy, Jonas Raymond; Siersen, Hans Erik; Bonde, Christian T

    2011-01-01

    A clinical case of the rare disorder steatocystoma multiplex is described in a 39-year-old female. The patient was diagnosed with generalized intradermal lesions that started presenting in early adulthood. There was no family history of similar lesions.Skin examination showed multiple, skin-colou...

  2. Primær kutan kryptokokkose hos dueavler

    DEFF Research Database (Denmark)

    Andersen, Kjeld; Ravn, Pernille; Bangsborg, Jette Marie

    2011-01-01

    A Danish 73 year-old male patient with polymyalgia rheumatica and in prednisone treatment presented with a cutaneous ulcer on the hand caused by a scratch from a pigeon. Initial treatment with antibiotics was unsuccessful. Biopsy revealed Cryptococcus neoformans and the patient recovered on antif...

  3. ”Tvivl, dobbelt ironi og sund fornuft hos Montaigne”

    DEFF Research Database (Denmark)

    Diderichsen, Adam

    2006-01-01

    Det vises, at Montaignes berømte skepticisme og religiøse tolerance er baseret på en bestemt tekstuel strategi, som man ville kunne kalde dobbeltironi, og som består i, at subjektet for en bestemt udtalelse bestandigt underminerer den subjektposition, som det selv taler ud fra. Problemet ved at f...

  4. Med på en lytter hos krigsfangerne

    DEFF Research Database (Denmark)

    Andersen, Steen

    2013-01-01

    Anmeldelse af: Sönke Neitzel og Harald Welzer: Soldater – Om krig, drab og død. Oversat fra tysk af Peter Dürrfeld efter 'Soldaten, Protokolle vom Kämpfen, Töten und Sterben'. Kristeligt Dagblads Forlag, 506 sider.......Anmeldelse af: Sönke Neitzel og Harald Welzer: Soldater – Om krig, drab og død. Oversat fra tysk af Peter Dürrfeld efter 'Soldaten, Protokolle vom Kämpfen, Töten und Sterben'. Kristeligt Dagblads Forlag, 506 sider....

  5. Venøse tromboser hos børn

    DEFF Research Database (Denmark)

    Tuckuviene, Ruta; Johnsen, Søren Paaske; Helgestad, Jon

    2008-01-01

    of thrombophilia is uncertain. International guidelines recommend screening for thrombophilia as part of the diagnostic set-up in children with thrombosis. Treatment of paediatric thrombosis with low-molecular-weight heparin appears safe, but the effectiveness remains to be established. Udgivelsesdato: 2008-Oct-20...

  6. Kontinuerlig glukosemonitorering kan have betydning hos gravide med diabetes

    DEFF Research Database (Denmark)

    Madsen, Anne Bjerrum; Secher, Anna L; Damm, Peter;

    2011-01-01

    In this review the use of continuous glucose monitoring (CGM) in pregnancy complicated by type 1 and type 2 diabetes is examined. Fourteen relevant articles were identified. Observational studies demonstrated that CGM was feasible during pregnancy without severe side effects. One randomised...... controlled trial resulted in improved metabolic control and reduced risk of macrosomia in women randomised to CGM. Future studies on the use of CGM in pregnancy are awaited with interest....

  7. Laparoskopisk splenektomi for hereditaer sfaerocytose hos børn

    DEFF Research Database (Denmark)

    Petersen, Christine Rønne; Bulut, Orhan; Jess, Per

    2008-01-01

    Based on the positive international experience with laparoscopic splenectomy on a large number of patients since 1991, we treated two teenagers with symptomatic hereditary spherocytosis and moderate splenomegaly. Both operations and postoperative courses were uneventful, and the children had...

  8. Det romantisk Fantastiske - Enhed og splittelse hos Edgar Allan Poe

    OpenAIRE

    Landsvig, Jeanette

    2016-01-01

    This thesis is called ‘The Romantic Fantastic – division and unity in Edgar Allen Poe’s’ and is about the literary phenomenon called the Fantastic (or Gothic) and the 19th century American author, Edgar Allan Poe. Today one of the three most frequently dealt with authors in the field of literary criticism, but in his own time considered an enfant terrible, a “merchant of death”. The claim of this thesis is that his American contemporaries neglected Poe because he understood to mediate bet...

  9. Traumatisk distal humerus-epifysiolyse hos nyfødt

    DEFF Research Database (Denmark)

    Al-Aubaidi, Zaid; Nielsen, Keld Daubjerg

    2010-01-01

    Traumatic distal humerus epiphysiolysis (TDHE) is a rare injury in infants with an incidence of about 1:35,000 births. It is primarily a birth injury, but it is also seen in cases of battered child syndrome. Because of its rare occurrence and the diagnostic difficulties, the lesion may be overloo...

  10. Alvorlige bivirkninger ved p-pillebrug hos teenagere

    DEFF Research Database (Denmark)

    Nylander, Malin Chatarina; Clausen, Helle V

    2014-01-01

    PubMed-search found studies investigating adverse effects of combined oral contraceptive pills (COC) among teenagers. Four studies found a small negative impact of COC on acquisition of bone mineral density. COC is associated with elevated risk of venous thrombotic events (VTE), especially during...

  11. Ultralydsskanning af lungerne hos den kritisk syge patient

    DEFF Research Database (Denmark)

    Jepsen, Søren Vad; Christiansen, Aage; Sloth, Erik

    2009-01-01

    Lung sonography is an old technique applied in a new fashion. Applying lung sonography in the examination of an acute patient with pulmonary problems is a novelty in Denmark. Applications, limitations, techniques, equipment and general principles for lung sonography are reviewed. We introduce the...... the "typical signs" such as lung sliding and artefacts. The rationale for lung ultrasonography in the treatment of acute patients seems obvious when comparing this technique with conventional diagnostic tools for the diagnosis of pulmonary status. Udgivelsesdato: 2009-Aug-31...

  12. Improved reliability of residential heat pumps; Foerbaettrad driftsaekerhet hos villavaermepumpar

    Energy Technology Data Exchange (ETDEWEB)

    Haglund Stignor, Caroline; Larsson, Kristin; Jensen, Sara; Larsson, Johan; Berg, Johan; Lidbom, Peter; Rolfsman, Lennart

    2012-07-01

    Today, heat pump heating systems are common in Swedish single-family houses. Many owners are pleased with their installation, but statistics show that a certain number of heat pumps break every year, resulting in high costs for both insurance companies and owners. On behalf of Laensfoersaekringars Forskningsfond, SP Energy Technology has studied the cause of the most common failures for residential heat pumps. The objective of the study was to suggest what measures to be taken to reduce the number of failures, i.e. improving the reliability of heat pumps. The methods used were analysis of public failure statistics and sales statistics and interviews with heat pump manufacturers, installers, service representatives and assessors at Laensfoersaekringar. In addition, heat pump manuals have been examined and literature searches for various methods for durability tests have been performed. Based on the outcome from the interviews the most common failures were categorized by if they; 1. Could have been prevented by better operation and maintenance of the heat pump. 2. Caused by a poorly performed installation. 3. Could have been prevented if certain parameters had been measured, recorded and followed up. 4. Are due to poor quality of components or systems. However, the results show that many of the common failures fall into several different categories and therefore, different types of measures must be taken to improve the operational reliability of residential heat pumps. The interviews tell that failures often are caused by poor installation, neglected maintenance and surveillance, and poor quality of standard components or that components are used outside their declared operating range. The quality of the installations could be improved by increasing installers' knowledge about heat pumps and by requiring that an installation protocol shall be filled-in. It is also important that the owner of the heat pump performs the preventive maintenance recommended by the manufacturer and that he/she surveys parameters indicating if satisfying operating conditions are maintained. Another example that could improve the reliability is that the heat pump system is regularly checked by a professional heat pump service technician. Components with sometimes poor quality can for example be temperature sensors, valves and circulations pumps. Compressor failures are often due to the fact that the heat pump of some reason, operates too much outside or close to the usage limits for the compressor and are not necessarily due to poor quality of the component itself.

  13. Eksperimentel bakteriofagterapi til behandling af kronisk Pseudomonas aeruginosaotitis hos hund

    DEFF Research Database (Denmark)

    Moodley, Arshnee; Mølgaard, Jesper

    2016-01-01

    Vi beskriver en case med anvendelsen af bakteriofager til behandling af kronisk otitis forårsaget af multiresistente Pseudomonas aeruginosa som en sidste behandlingsmulighed før aflivning. Trods gentagne behandlinger, både topikalt og systemisk, med op til seks forskellige antibiotika over en...

  14. Kirurgisk behandling af fedme hos børn

    DEFF Research Database (Denmark)

    Hansen, Ann Berit; Gögenur, Ismail; Støckel, Mikael

    2014-01-01

    Morbid obesity in teenagers has become an increasing problem. Conventional diet has not yet shown effective long-term weight loss. Alternatively, bariatric surgery on adolescents has resulted in substantial weight loss, recovery from diabetes, improvement of cardiovascular risk factors...... and improvement in psychosocial status. Still, surgery performed on adolescents provides ethical challenges such as the unknown long-term prognosis after surgery. Despite these challenges, in cases of severe intractable obesity or development of life-threatening complications due to obesity, surgery should...

  15. HIV hos ældre kvinder efter udlandsrejse

    DEFF Research Database (Denmark)

    Jespersen, Sanne; Thorsteinsson, Kristina; David, Kim Peter

    2016-01-01

    We report two cases of HIV infection among female travellers of older age. A Danish woman in her eighties was diagnosed with acute HIV infection after travelling to West Africa. A sexual history was not recorded before her third hospital visit. A West African woman in her seventies who had been...... living in Denmark for 40 years was diagnosed with advanced HIV after having been to West Africa for family visits. We want to emphasize that women of older age also have sex that may put them at risk of HIV, that febrile returning travellers should be tested for HIV, and that presence of HIV indicator...... diseases should lead to HIV testing....

  16. Galdesten og komplikationer i forbindelse med galdestenssygdom hos statinbehandlede patienter

    DEFF Research Database (Denmark)

    Roepstorff, Søren; Engelbrechtsen, Line

    2015-01-01

    Statins are a widely used group of drugs which can lower cholesterol levels. Recently, there has been emerging evidence that statins may decrease the formation of cholesterol gallstones and several studies have reported invert association between symptomatic cholesterol gallstones and statin use....... Subsequent evidence for decrease in gallstone-associated complications among statin users have not been clearly described. In this review we summarize current evidence for the association between statin use and the risk of gallstone-associated complications....

  17. Fotodynamisk behandling af kolangiokarcinom hos 80-årig

    DEFF Research Database (Denmark)

    Ulstrup, Thomas; Pedersen, Finn Møller

    2013-01-01

    70% of cholangiocarcinomas (CC) are perihilar lesions. At the time of diagnosis few are candidates for complete resection, and the standard palliative therapy has been biliary stenting. Studies have shown that photodynamic therapy (PDT) improves survival time. In this case report we describe an 8...

  18. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    Bisphosphonate-associated osteonecrosis of the jaw (BON) is mainly observed in patients with multiple myeloma, and to a lesser extent in breast and prostate cancer patients receiving intravenous treatment with potent bisphosphonates. The incidence of BON increases with the duration of bisphosphon...

  19. H1N1 Influenza A hos mennesker og svin

    DEFF Research Database (Denmark)

    Larsen, Lars Erik

    2009-01-01

    Den nye pandemiske influenza A stamme H1N1 er hovedsagelig et nyt virus, som spredes mellem mennesker, men virusset er formodentlig opstået ved blanding af to svineinfluenza-virus og har derfor bibeholdt evnen til at kunne smitte fra mennesker til svin og fra svin til svin. Det er derfor vigtigt...

  20. Klinisk kemiske parametre for metabolisk kontrol hos diabetespatienter

    DEFF Research Database (Denmark)

    Sindrup, S H; Matzen, L E; Wengler, K;

    1989-01-01

    Fructosamine and various measures of blood glucose were compared to glycosylated hemoglobin as indices of glycaemic control in 148 patients with insulin treated diabetes. Fructosamine correlated fairly well with glycosylated hemoglobin (r = 0.67), but around 40 per cent of the patients...... with glycosylated hemoglobin below upper reference limit had a fructosamine value over upper reference limit and vice versa. The possibility to predict the level of glycosylated hemoglobin from fasting blood glucose, postprandial blood glucose, and self-measured blood glucose was poor. The difference in self......-measured blood glucose from patients with high versus low levels of glycosylated hemoglobin was very modest (0.5-2.0 mmol/l). It is concluded that it is reasonable to measure both glycosylated hemoglobin and fructosamine to evaluate glycaemic control in insulin treated diabetic patients. Fasting blood glucose...

  1. H1N1 Influenza A hos mennesker og svin

    DEFF Research Database (Denmark)

    Larsen, Lars Erik

    2009-01-01

    Den nye pandemiske influenza A stamme H1N1 er hovedsagelig et nyt virus, som spredes mellem mennesker, men virusset er formodentlig opstået ved blanding af to svineinfluenza-virus og har derfor bibeholdt evnen til at kunne smitte fra mennesker til svin og fra svin til svin. Det er derfor vigtigt...

  2. Persisterende pulmonal hypertension hos nyfødte

    DEFF Research Database (Denmark)

    Pedersen, C M; Hansen, T G; Henneberg, Steen Winther;

    1997-01-01

    On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorpo......On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation...

  3. Multipel graviditet hos kvinder med korrigeret Steno-Fallots tetralogi

    DEFF Research Database (Denmark)

    Pedersen, Lia Mendes; Pedersen, Thais A; Herskind, Anne Maria

    2008-01-01

    Tetralogy of Fallot is the most common cyanotic heart disease accounting for 5 to 8% of all cases of congenital heart disease. In a cohort of women with corrected Tetralogy of Fallot, followed concerning fertility and pregnancy outcome, we observed two cases of uncomplicated multiple pregnancies....... Such pregnancies have not previously been described. Despite the overload on the operated heart resulting from a multiple pregnancy, both women experienced uncomplicated pregnancies and deliveries of healthy children. This reflects the good hemodynamic results of complete repair and meticulous pregnancy follow...

  4. Tyndtarmstransplantation som behandling af tarmsvigt hos børn

    DEFF Research Database (Denmark)

    Thøstesen, Lisbeth Marianne; Qvist, Niels; Rasmussen, Allan

    2010-01-01

    Parenteral nutrition is the main treatment of intestinal failure. In cases with irreversible intestinal failure and life-threatening complications to parenteral nutritional treatment, transplantation of the intestine may be considered. Post-transplantation survival has increased markedly during...

  5. Dyb venetrombose i penis hos patient med malign sygdom

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Ajan, Rullah

    2014-01-01

    Thrombosis of the deep penile venous system in a patient with a malignant disease Thrombosis of the deep penile venous system is extremely rare and must be clearly distinguished from superficial thrombosis because it may cause serious clinical complications. We present a 76-year-old man with thro...... with thrombosis of the vena dorsalis penis profunda three months after being diagnosed with disse­m­­inated non-small cell lung cancer. Total remission of the thrombosis was achieved with daily subcutaneous injections with heparin for four weeks....

  6. Biogas potential in Grasses from Wetlands; Biogaspotential hos vaatmarksgraes

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Marvin

    2009-12-15

    The purpose of this study has been to survey wetlands that are suitable for mowing and to analyze the biogas potential in the harvested grasses. A preformed investigation showed that there are suitable wetlands, which can be harvestable, namely those mowed formerly in traditional haymaking. The practice of traditional haymaking is dying out in Sweden today but there are several good reasons why it should to be reconsidered. Nature- and cultural values are obvious, also the unutilized energy in the grass. The suitable types of wetland that were specifically studied were the productive wetlands; meadow marshes and wet meadows. These wetlands are represented in the Swedish meadow- and pasture inventory database; (TUVA) and the Swedish national wetland inventory (VMI). Going through the databases showed that they largely complement each other. A geographical mapping was also carried out of wetlands in relation to areas of interest for the future establishment of biogas plants, so called 'hotspots'. The geographical survey shows that there is ample amount of grass from wetlands within a 30-kilometer radius that can supplement the plants main substrate, manure. The map layer Swedish Ground Cover Data (SMD) together with GIS software was used to analyze the extent of overgrowth for the older VMI objects in Uppsala County, with the result that half of the VMI objects are no longer of interest. They have become either woodland and bogs, or reed beds. There is very little information on wetland-grasses and methane production. Instead, a theory was evaluated regarding the possibility of transforming nutritional values for grass and sedges into biogas potentials. It was shown that this method does not capture the total biogas potential, but offers a minimum value that can be considered rather reliable. The energy transformation showed that late harvested grasses from wetlands has a biogas potential about 0,21 Nm3 methane/ (kg, DM) which is about 60 % of the biogas potential for grass-legume forages. The gas yield after 20 days is also relatively low. It could though be favorable to try grasses from wetlands in methane production, because co-digestion with these grasses and other suitable materials could produce a higher net gas yield for the plant, than using the materials solely by themselves. The derived biogas potential showed that there is at least 4, 4 GWh biogas energy in grasses from wetlands in Uppsala county at a low estimate. Harvesting costs were however shown to be too high in the present to achieve a plus result

  7. Field cancerization i ansigtet hos en ung kvindelig svejser

    DEFF Research Database (Denmark)

    Kristensen, Rasmus Nygård; Sørensen, Jens Ahm

    2015-01-01

    developed multiple squamous cell carcinomas located exclusively on the right side of her face. During welding she had experienced numerous facial burns limited to the right side. This marked anatomical relationship between exposure and illness supports a causal association between welding and skin cancer.......Welding generates ultraviolet radiation and has been suggested to cause skin cancer. However, it remains questionable whether welding is in fact causally associated with the development of skin cancer. We report on a 44-year-old female with ten years occupational experience as a welder, who...

  8. Varicella-zoster-infektion kompliceret med bakteriel pneumoni hos barn

    DEFF Research Database (Denmark)

    Wolthers, Benjamin Ole; Thiested, Ebbe; Gyhrs, Anette F

    2015-01-01

    This case report describes how a three-year-old girl referred to our paediatric ward, infected with varicella-zoster virus and a bacterial pneumonia causing atelectasis. The girl did not respond to initial treatment with intravenous antibiotics. Only after a lung drain was inserted she gradually...... recovered. We briefly describe the incidence of bacterial pneumonia as a complication to varicella-zoster virus and raise the question whether to vaccinate against varicella-zoster virus....

  9. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Meulengracht Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...

  10. Neurogen dysfagi ses hyppigt hos patienter på intensivafdelinger

    DEFF Research Database (Denmark)

    Pedersen, Anette Barbre; Kjærsgaard, Annette; Larsen, Jens Rolighed

    2015-01-01

    Neurogenic oropharyngeal dysphagia (NOD) is a frequent condition in neurological patients admitted to the ICU, particularly in patients with brainstem lesions. The CNS damage itself can predispose to dysphagia, but also the treatment and preventive measures may predispose to and exacerbate...... rehabilitation is important....

  11. Myopati hos en patient i behandling med simvastatin og fluconazol

    DEFF Research Database (Denmark)

    Pedersen, Jens Kristian; Lydolph, Magnus Christian; Somnier, Finn

    2016-01-01

    A 69-year-old female was admitted due to progressive loss of muscle strength following addition of fluconazole to long-term simvastatin treatment. Rhabdomyolysis was suspected and both drugs were discontinued. Forced diuresis was initiated together with a short course of prednisolone. After 21...

  12. Karkirurgisk behandling hos patienter med påvirket nyrefunktion

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Lorentzen, Jørgen Ewald

    1994-01-01

    and blood pressure status was evaluated preoperatively and at follow-up. The perioperative mortality was 5% (n = 2) and morbidity 21% (n = 9). At discharge from hospital renal function was maintained in 38 patients (90%), including three patients who at the time of operation were without diuresis and had...

  13. Pancreastraumer hos børn--operativ versus nonoperativ behandling

    DEFF Research Database (Denmark)

    Haugaard, Michael Valentin; Penninga, Luit; Ifaoui, Inge Bøtker-Rasmussen;

    2012-01-01

    Pancreatic trauma is more frequent in children than in adults and is often caused by trauma to the upper part of the abdomen. Mortality is low, but morbidity is high. Pancreatic trauma can be treated operatively or non-operatively, but there is disagreement about the optimal treatment strategy...

  14. Nyre- og urinvejsabnormiteter hos småbørn

    DEFF Research Database (Denmark)

    Cortes, D; Lee, K; Thorup, J M

    1999-01-01

    were diagnosed. From 1994-1996 a total of 35 children younger than two years of age were found to have urological abnormalities. Fourteen patients had a ultrasonographical prenatally diagnosed urological abnormality, which was confirmed postnatally. Twenty-one children were diagnosed with urological...... of urological abnormalities was 0.25% in children younger than two years of age in Frederiksborg county. In conclusion, in 1994-1996 the frequency and pattern of urological abnormalities in Frederiksborg county was in accordance with the figures in the literature. Urological abnormalities requiring treatment...

  15. Persisterende pulmonal hypertension hos nyfødte

    DEFF Research Database (Denmark)

    Pedersen, C M; Hansen, T G; Henneberg, S W

    1997-01-01

    On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorpo...

  16. Traethedsbrud af collum femoris hos rask maratonløber

    DEFF Research Database (Denmark)

    Nielsen, Klaus; Christensen, Ole; Lukina, Guy Feruzi

    2009-01-01

    Fatigue fractures of the hip are rare causes of hip pain. Delayed diagnostics of this type of fracture can cause serious complications. We describe a case concerning a 32-year-old male amateur runner who experienced hip pain with rapid onset during his first marathon. After eight days his general...

  17. Primaer cerebral vaskulitis hos børn

    DEFF Research Database (Denmark)

    Pradsgaard, Dan Østergaard; Stausbøl-Grøn, Brian; Østergaard, John Rosendahl;

    2010-01-01

    detected by magnetic resonance were diagnosed with primary CNS vasculitis. Age at onset was three to 12 years. Acutely acquired hemiparesis was seen in five children, two had facial palsy. Among other symptoms were headache, ataxia, dysarthria, loss of consciousness and seizures. Only modest changes......INTRODUCTION: Primary cerebral vasculitis in children is a newly recognized, rare inflammatory condition affecting the vessels of the brain. It is characterized by newly acquired neurological deficit(s) with angiographic or histological evidence of central nervous system (CNS) vasculitis...

  18. Laktat i navlearterie- og navleveneblod hos nyfødte

    DEFF Research Database (Denmark)

    Rubak, Sune Leisgaard Mørck; Henriksen, Tine Brink

    2010-01-01

    in arterial umbilical cord blood was higher than in venous umbilical cord blood; furthermore, that O2 and pH in arterial umbilical cord blood were lower than in venous umbilical cord blood. Regression analysis including the factors lactate and "active second stage of labour" showed that lactate significantly......INTRODUCTION: In theory, lactate may be used as a more precise measure of the degree of metabolic acidosis than other previous methods, thereby enabling differentiation between acute and chronic foetal hypoxia. The aim of the study was to describe lactate in arterial and venous cord blood...... in an unselected population of newborn children without signs of foetal hypoxia or perinatal asphyxia. MATERIAL AND METHODS: The study included 208 newborn children. The umbilical cord of the children was double clamped within 30 seconds and thereafter blood was drawn from an umbilical arterial and venous cord...

  19. Livskvalitet efter aortaklapoperation hos patienter > or = 75 år

    DEFF Research Database (Denmark)

    Petersen, Rasa Skrupskelyte; Poulsen, Anja

    2010-01-01

    A growing number of elderly undergo surgery of the aortic valve. It is therefore important to investigate their postoperative course concerning quality of life.......A growing number of elderly undergo surgery of the aortic valve. It is therefore important to investigate their postoperative course concerning quality of life....

  20. Miltabsces hos en 28-årig, tidligere rask mand

    DEFF Research Database (Denmark)

    Eriksen, Nina Marie Birk; Lynggard, Charlotte Duch; Kronborg, Gitte

    2011-01-01

    A 28 year-old, previously healthy man was hospitalised with acute abdominal pain and a high fever. During six months the patient had suffered from severe pain in his left shoulder, left part of the thorax and over time also in the upper part of the abdomen. When hospitalised he showed biochemical...... signs of infection and a computer tomography of the abdomen revealed an 11 cm abscess in the spleen. Non-haemolytic streptococci were found after aspiration. Initially the abscess was treated with antibiotics and ultrasound-guided drainage. Due to lack of curative effect of drainage splenectomy...

  1. Hyppigheden af selvrapporteret alkoholpåvirkning hos tilskadekomme cyklister

    DEFF Research Database (Denmark)

    Larsen, L B; Larsen, Claus Falck; Kain, H;

    1995-01-01

    The aim of the study was to determine the frequency of self reported alcohol influence in injured bicyclists. The study was based upon a combination of data from a questionnaire and recordings from the emergency room. Eighteen percent of cyclists 15 years of age or older treated at the emergency...... room reported themselves influenced by alcohol at the time of accident. The highest injury rate in patients riding under influence was found in the age group 20-29 years, and the proportion of injured cyclists riding under influence was four times higher in males than in females. The lesions sustained...

  2. Progressiv multifokal leukoencefalopati hos en patient med myelomatose

    DEFF Research Database (Denmark)

    Willert, Cecilie Balslev; Engsig, Frederik Neess; Eskildsen, Helle Wulf;

    2014-01-01

    Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease in the central nervous system. It is caused by reactivation of John Cunningham-virus and has a grave prognosis. PML occurs most frequently in HIV-patients, but can also be seen in patients with iatrogenic immunodefic...

  3. Toksisk shock syndrom. Et tilfoelde hos et barn med forbroending

    DEFF Research Database (Denmark)

    Glazowski, M J; Ostergaard, G Z; Arpi, M

    1992-01-01

    A case of the toxic shock syndrome (TSS) in a burnt (scalded) child is presented. TSS is a condition most frequently associated with menstruating women using tampons. In recent years, however, increased knowledge of the syndrome has led to an increase in the number of reported cases associated...

  4. Biologiske forandringer hos pasienter med post-traumatisk stresslidelse

    OpenAIRE

    Haugsbø, Erik Sole

    2008-01-01

    Abstract Post-traumatic stress disorder (PTSD) is a serious psychiatric disorder that may develop in individuals exposed to a traumatic event. The lifetime prevalence of traumatic events serious enough to cause subsequent PTSD shows great variation depending on definition and sample selection, but even the most conservative of estimates would propose that in excess of 300 million patients world-wide meet diagnostic criteria for PTSD. PTSD is a disorder that leads to substantial impairment...

  5. Emosjonsregulering og motivasjon hos barn med AD/HD

    DEFF Research Database (Denmark)

    Høvik, Marie Farstad; Plessen, Kerstin J

    2010-01-01

    Impaired cognitive control functions have long been regarded as the main problem in the development of Attention-Deficit/Hyperactivity Disorder (ADHD). A more recent model emphasizes the importance of emotional and motivational problems. We have reviewed the evidence for this model, which may hav...

  6. Brugen af personas hos danske virksomheder - 2012/13

    DEFF Research Database (Denmark)

    Nielsen, Lene; Nielsen, Kira Storgaard

    2013-01-01

    Denne rapport er skrevet på baggrund af et projekt initieret og finansieret af InfinIT – Innovationsnetværket for IT. Formålet med projektet er at undersøge hvorledes personas i dag etableres, kommunikeres, anvendes og vedligeholdes i forskellige typer af virksomheder samt etablere et opdateret sæt...... af anbefalinger for deres anvendelse. Virksomheders erfaringer med personas vil blive adresseret fra to forskellige vinkler:. Fokus vil bl.a. være på hvordan personas udvikles og vedligeholdes, om og hvordan de bruges, og hvad de bruges til. Personas er beskrivelser af fiktive brugere og bruges i...... designprocesser. Beskrivelserne er skabt på baggrund af data indsamlet om slutbrugerne. En samling af personas, som regel mellem 2 og 6 beskrivelser, vil i denne rapport benævnes et personasæt. Når personabeskrivelserne indgår i designprocessen bruges de til at få ideer til og beskrive, hvordan brugerne vil...

  7. Stresshyperglykaemi hos et barn med svaer akut gastroenteritis

    DEFF Research Database (Denmark)

    Bjerre, Jesper V.

    2002-01-01

    A case of a two years and ten months old girl with severe acute gastroenteritis, dehydration, and hyperglycaemia is described. Transient hyperglycaemia is a common clinical finding in children under stress. We discuss the distinction between hyperglycaemia as a prediabetic state and that as a phy...

  8. Emosjonsregulering og motivasjon hos barn med AD/HD

    DEFF Research Database (Denmark)

    Høvik, Marie Farstad; Plessen, Kerstin J

    2010-01-01

    Impaired cognitive control functions have long been regarded as the main problem in the development of Attention-Deficit/Hyperactivity Disorder (ADHD). A more recent model emphasizes the importance of emotional and motivational problems. We have reviewed the evidence for this model, which may have...

  9. Udvikling af sklerodermisk krise hos patient med uerkendt sklerodermi

    DEFF Research Database (Denmark)

    Madsen, Kristine Lindhard; Hansen, Alastair; Halberg, Poul

    2014-01-01

    Less than 10% of the patients with systemic scleroderma develop renal crisis, i.e. acute renal failure and severe hypertension in most cases. Kidney biopsy shows hypertensive arteriolar changes. This complication was lethal until treatment with captopril was introduced in 1976. Since that time...

  10. ”Tvivl, dobbelt ironi og sund fornuft hos Montaigne”

    DEFF Research Database (Denmark)

    Diderichsen, Adam

    2006-01-01

    Det vises, at Montaignes berømte skepticisme og religiøse tolerance er baseret på en bestemt tekstuel strategi, som man ville kunne kalde dobbeltironi, og som består i, at subjektet for en bestemt udtalelse bestandigt underminerer den subjektposition, som det selv taler ud fra. Problemet ved...... at forstå Montaignes forhold til religion er derfor ikke så meget - sådan som det traditionelt er blevet antaget - at fastslå, om hans udsagn om dette emne er ironiske eller alvorligt ment. Problemet er snarere at fastslå, om selve ironien er alvorligt eller ironisk ment....

  11. Laktat i navlearterie- og navleveneblod hos nyfødte

    DEFF Research Database (Denmark)

    Rubak, Sune Leisgaard Mørck; Henriksen, Tine Brink

    2010-01-01

    . The inclusion criteria were gestational age above 35 weeks and no signs of foetal hypoxia or perinatal asphyxia. RESULTS: Out of 208 newborn children, 105 children were excluded in accordance with the above criteria, thus the remaining 103 newborn children were included. We demonstrated that lactate and CO2...

  12. Operation for ingvinalhernie og fertilitet hos mænd

    DEFF Research Database (Denmark)

    Kohl, Andreas; Andresen, Kristoffer; Rosenberg, Jacob

    2016-01-01

    It is still unknown whether or not inguinal hernia repair with or without the use of mesh causes infertility in male patients. The objective of this article was to discuss the available literature, to ascertain if the preclinical and clinical findings point towards a causal relationship. The review...

  13. Peritoneal tuberkulose hos patient med formodet dissemineret ovariecancer

    DEFF Research Database (Denmark)

    Madsen, Lone Wulff; Neumann, Gudrun; Pedersen, Court

    2012-01-01

    imaging) supported this suspicion. Peritoneal biopsy from laparoscopy showed granulomas with central necrosis. Microscopy, culture and polymerase chain reaction from biopsy samples were negative for Mycobacterium tuberculosis. Follow-up with a CT scan after six months of full tuberculosis treatment showed...... normal conditions. Peritoneal tuberculosis is a diagnostic challenge, but should be considered in case of immigrants from high-risk areas....

  14. Stressfrakturer af distale fibula hos en patient med osteoporose

    DEFF Research Database (Denmark)

    Schwartz, Frederik; Heerfordt, Ida Marie

    2014-01-01

    We report a case of an 81-year-old osteoporotic woman, who suffered stress fractures of the distal fibula on both sides within a two-year period. The risk factors for stress fractures are reviewed and the importance of a high index of suspicion for stress fractures is emphasized. When a stress...... fracture is suspected it should lead to plain radiography and treatment with protected weight-bearing with crutches or a brace....

  15. Kognitive og emotionelle forandringer hos klienter i metadonvedligeholdelsesbehandling

    DEFF Research Database (Denmark)

    Aagesen, Niels Skovby

    2004-01-01

      There has for some time been diverse opinions concerning the effect of methadone on the cognitive and emotional functions in man. The present work attempts a critical overview of the existing research in this area, drawing some conclusions regarding the effect of methadone on the affected...... functions: 1) Concerning cognitive functions, the apparent negative effect of methadone is restricted to short time memory, and 2) apparently methadone have negative effects on emotional functioning in the areas of empathy and attachment, and a positive effect in the areas of depression and anxiety. At last...... some conclusions are drawn concerning the clinical use of methadone....

  16. Cirkulatorisk kollaps hos bodybuilder i forbindelse med anaestesi

    DEFF Research Database (Denmark)

    Ravn, Toke; Afshari, Arash; Nielsen, Jeppe Sylvest

    2010-01-01

    The use of anabolic steroids is a growing problem in Denmark. The effects and side effects caused by anabolic steroids in relation to anaesthesia are poorly described. This article describes a case of circulatory collapse in a young bodybuilder during anaesthesia. The primary cause of the collapse...

  17. Det udstødtes poesi hos Sara Stridsberg

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2014-01-01

    Det synes at være et gennemgående projekt i Sara Stridsbergs forfatterskab at genoprejse en række upopulære, eller i hvert fald tvivlsomme og angribelige, kvindeskikkelser – hvad enten vi taler om historiske personer eller fiktive karakterer: Sally Bauer, Valerie Solanas, Medea, Lolita. Artiklen...

  18. Venskaber hos børehavebørn

    DEFF Research Database (Denmark)

    Broström, Stig

    2017-01-01

    I kapitlet beskrives børns sociale kompetencer som forudsætning for dannelse af venskaber. Med afsæt i Deweys og Vygotsky forståelse af begrebet social interaktion undersøges hvilke komponenter børns sociale samspil og sociale kompetencer består af samt hvilke mønstre eller former for social...

  19. Læringsmodstand hos børn

    DEFF Research Database (Denmark)

    Broström, Stig

    2017-01-01

    I dette kapitel beskrives dimensioner ved børns læring og med særligt fokus på Illeris’ begreb læringsmodstand. Det tages udgangspunkt i den kulturhistoriske skoles læringsteori med reference til bl.a. Vygotsky og Leontjev. Børn i såvel dagtilbud som skolen vil løbende vise modstand mod læring...

  20. Måling af helbredsrelateret livskvalitet hos patienter med thyroideasygdomme

    DEFF Research Database (Denmark)

    Watt, Torquil; Feldt-Rasmussen, Ulla; Rasmussen, Ase Krogh;

    2008-01-01

    -relevant questions about HRQL and thyroid disease remain unanswered and the current sparse results are contradictory. This may be due to the lack of a valid HRQL measurement. Hopefully, increased focus on HRQL and the development of a valid thyroid-specific HRQL measure will improve this status. Udgivelsesdato: 2008...

  1. Laktatacidose hos en yngre kvinde med status asthmaticus

    DEFF Research Database (Denmark)

    Ramazan-Yousif, Lana; Albertsen, Signe; Bergmann, Troels K

    2017-01-01

    A 24-year-old woman with asthma presented with symptoms of upper airway infection and tachypnoea and wheezes. She had a history of admissions to intensive care units (ICU) due to respiratory insufficiency. The initial lactate concentration was 2.1 mmol/l. The treatment consisted of inhaled...

  2. Akut underernæring hos børn

    DEFF Research Database (Denmark)

    Rytter, Maren Johanne Heilskov; Michaelsen, Kim F.; Friis, Henrik

    2017-01-01

    The prevalence of malnutrition has declined significantly over the last 30 years. Despite this, malnutrition remains a major cause of illness and death among children worldwide, particularly in low- and medium-income countries. Marasmus and kwashiorkor are the most life-threatening forms of malnu......The prevalence of malnutrition has declined significantly over the last 30 years. Despite this, malnutrition remains a major cause of illness and death among children worldwide, particularly in low- and medium-income countries. Marasmus and kwashiorkor are the most life-threatening forms...

  3. Omdannelse af sukker og andre kulhydrater til fedt hos mennesker

    DEFF Research Database (Denmark)

    Quistorff, Bjørn; Grunnet, Niels

    2003-01-01

    The basic biochemistry of de novo lipogenesis and the current understanding of fat formation from carbohydrates in humans are reviewed. The suggestion is made that ingestion of carbohydrates in excess of the caloric needs necessarily results in de novo lipogenesis since the glycogen stores...

  4. Overvekt hos gravide – en utfordring i svangerskapsomsorgen

    Directory of Open Access Journals (Sweden)

    Wenke Moldjord

    2015-12-01

    Results: The informants were aware that obesity in pregnancy may cause complications for both mother and child, but they experienced obesity and lifestyle changes as challenging in antenatal care. Weight and body were perceived as something vulnerable. Informants found it hard to talk about weight because they were afraid of reactions from the pregnant women. They also expressed insecurity regarding their own expertise when it comes to communication and nutrition. Informants expressed the need for more interdisciplinary cooperation between different health workers in community health. They experienced such cooperation difficult to achieve.

  5. Parvovirus B19-akut hepatitis hos immunkompetent patient

    DEFF Research Database (Denmark)

    Larsen, Lykke

    2011-01-01

    This article describes a case of acute hepatitis in an adult person without subsequent complications caused by parvovirus B19 (PVB19). The diagnosis was made by detection of PVB19 IgM and IgG antibody in the blood using ELISA. There was not made any affirmative polymerase chain reaction for DNA...

  6. Fysisk og mental belastning hos kirurgen under minimalt invasiv kirurgi

    DEFF Research Database (Denmark)

    Munch-Petersen, H.R.; Rosenberg, J.

    2008-01-01

    Minimally invasive surgery (MIS) is in theory more physically and mentally demanding than open surgery. This aspect is due to the inherent limits of MIS. The implementation of high-technological operating rooms and the development of ergonomically more useful instruments have not been documented ...... scientifically, nor has the question of whether or not MIS is a contributing problem in itself in the surgeon's work been documented. There is a need for clinical investigations with establishment of methodological models of the ergonomics in MIS Udgivelsesdato: 2008/2/18......Minimally invasive surgery (MIS) is in theory more physically and mentally demanding than open surgery. This aspect is due to the inherent limits of MIS. The implementation of high-technological operating rooms and the development of ergonomically more useful instruments have not been documented...

  7. Sömn, TV och datorvanor hos skolbarn

    OpenAIRE

    Garmy, Pernilla

    2011-01-01

    The aim of the study was to investigate sleep duration, difficulties in sleeping, feelings of tiredness at school, television and computer habits, among primary school children. A questionnaire concerning television and computer habits and length of sleep was given to 208 children8-12 years of age from two public primary schools in southern Sweden in 2007 and 2008. For each of the school grades involved, differences in television and computer habits between children sleeping less than the med...

  8. Akutt lymfatisk leukemi hos barn i Norge 1992-2000

    DEFF Research Database (Denmark)

    Kolmannskog, Svein; Flaegstad, Trond; Helgestad, Jon

    2007-01-01

    BACKGROUND: Acute lymphoblastic leukemia is the most common malignancy in childhood. The survival rate has increased steadily over the last 40 years. MATERIAL AND METHODS: All children aged 0-15 years and diagnosed in Norway in the period 1992-2000, were included in the study (n = 301...

  9. Perkutan endoskopisk gastrostomisonde hos børn med cancer

    DEFF Research Database (Denmark)

    Barlaug, Mari; Kruse, Aksel; Schrøder, Henrik

    2008-01-01

    INTRODUCTION: Malnutrition is common in children with cancer. Percutaneous endoscopic gastrostomy (PEG) is a well-established method to treat malnutrition. The objective of this study was to describe the complications and efficacy of PEG in paediatric cancer patients. MATERIALS AND METHODS: Between...

  10. Medicinsk behandling af vandladningsproblemer hos mænd

    DEFF Research Database (Denmark)

    Andersen, Jens Thorup; Nordling, Jørgen; Walter, Steen

    2007-01-01

    Lower Urinary Tract Symptoms (LUTS) e.g. in prostatic infravesical obstruction and symptoms of overactive bladder (OAB) in men can be treated effectively with drugs. The current evidence for use of alpha-adrenergic blocking agents, 5-alpha-reductase inhibitors, combination therapy and antimuscari...... by the administration of a loop-diuretic in the late afternoon. Udgivelsesdato: 2007-May-14...

  11. Forskellige metoder til kredsløbsmonitorering hos intensivpatienter

    DEFF Research Database (Denmark)

    Palsgaard Møller, Thea; Perner, Anders; Bülow, Hans-Henrik

    2012-01-01

    This article presents a mini medical technology evaluation of three less invasive monitoring techniques for monitoring cardiac output, CardioQ, ECOM and PiCCO, with focus on validation, usability and costs in intensive care. In conclusion, when identifying patients with low cardiac output, we...... suggest starting with simple screening tools (e.g. CardioQ or central venous O2 saturation), and when in doubt, upgrade to better validated, yet more time-consuming techniques (e.g. PiCCO using thermodilution). Also consults should be made to other intensive care units in terms of the practical...

  12. Pause med trombocytaggregationshaemmere hos kirurgiske patienter med kardiel stent

    DEFF Research Database (Denmark)

    Johansen, Mathias; Afshari, Arash; Kristensen, Billy

    2010-01-01

    Dual antiplatelet therapy with aspirin and clopidogrel is increasingly used for secondary prevention of cardiovascular events in patients with percutaneous coronary intervention. Anesthesiologists and surgeons are faced with the challenge of managing these patients prior to a surgical procedure. ....... Premature discontinuation of antiplatelet therapy constitutes a substantial risk of stent thrombosis, myocardial infarction and death. Continuing therapy increases the risk of bleeding. We provide the latest evidence on this topic for patients awaiting non-cardiac surgery....

  13. Tyndtarmstransplantation som behandling af tarmsvigt hos børn

    DEFF Research Database (Denmark)

    Thøstesen, Lisbeth Marianne; Qvist, Niels; Rasmussen, Allan

    2010-01-01

    Parenteral nutrition is the main treatment of intestinal failure. In cases with irreversible intestinal failure and life-threatening complications to parenteral nutritional treatment, transplantation of the intestine may be considered. Post-transplantation survival has increased markedly during...

  14. Hjertetamponade hos et praematurt barn med perkutant anlagt centralt venekateter

    DEFF Research Database (Denmark)

    Callesen, Michael T; Nielsen, Peter Ehlert

    2008-01-01

    We report a case of a premature girl born with a gestational age of 26 weeks who developed cardiac tamponade after displacement of a peripheral inserted central catheter. She recovered completely after an acutely performed pericardiocentesis. The pericardial fluid was consistent with parental...... nutrition. Pericardiac effusion must be suspected in children with central catheters and sudden cardiovascular decompensation. This article discusses recommended positioning of peripherally inserted central catheters....

  15. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    deficits by means of a standardised method for measurement of distance. A second purpose was to investigate the influence of preoperative fMRI on the neurosurgical decision-making process. MATERIAL AND METHODS: Retrospective study of 25 patients. The inclusion criteria were surgery or biopsy after f...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend......%) and when deciding the extent of the surgical approach (83%). CONCLUSION: The standardised method for measurement of distance between tumour margin and fMRI activity can contribute to the preoperative risk assessment in patients with brain tumours....

  16. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Meulengracht Sørensen, Preben; Fründ, Torben

    2010-01-01

    deficits by means of a standardised method for measurement of distance. A second purpose was to investigate the influence of preoperative fMRI on the neurosurgical decision-making process. MATERIAL AND METHODS: Retrospective study of 25 patients. The inclusion criteria were surgery or biopsy after f...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend...... (50%) and when deciding the extent of the surgical approach (83%). CONCLUSION: The standardised method for measurement of distance between tumour margin and fMRI activity can contribute to the preoperative risk assessment in patients with brain tumours....

  17. Primaer cerebral vaskulitis hos børn

    DEFF Research Database (Denmark)

    Pradsgaard, Dan Østergaard; Stausbøl-Grøn, Brian; Østergaard, John Rosendahl

    2010-01-01

    INTRODUCTION: Primary cerebral vasculitis in children is a newly recognized, rare inflammatory condition affecting the vessels of the brain. It is characterized by newly acquired neurological deficit(s) with angiographic or histological evidence of central nervous system (CNS) vasculitis......, in the absence of other known diseases with these findings. MATERIAL AND METHODS: We performed a retrospective review of children below 15 years submitted with CNS vasculitis to the department between 1999 and 2008. RESULTS: Six (two boys, four girls) of ten children with clinical and vascular imaging findings...... detected by magnetic resonance were diagnosed with primary CNS vasculitis. Age at onset was three to 12 years. Acutely acquired hemiparesis was seen in five children, two had facial palsy. Among other symptoms were headache, ataxia, dysarthria, loss of consciousness and seizures. Only modest changes...

  18. Nydiagnosticeret kongenit transposition hos en 76-årig kvinde

    DEFF Research Database (Denmark)

    Sloth, Astrid Drivsholm; Jensen, Jesper Khedri; Steffensen, Flemming Hald

    2009-01-01

    A case of congenitally corrected transposition presenting for the first time with second-degree AV block in a 76-year-old woman is presented. This case demonstrates that congenitally corrected transposition can remain asymptomatic and undiagnosed, especially when no other cardiac defects are pres...

  19. Clearcellekarcinom i livmoderhalsen hos en 17-årig pige

    DEFF Research Database (Denmark)

    Rønneberg, Elisabeth Thal; Lidang, Marianne; Palle, Connie

    2014-01-01

    Clear cell adenocarcinoma of the uterine cervix (CCEA) is a rare disease, accounting for only 1% of all cervical cancers. The disease in young women is linked to diethylstilbestrol (DES) exposure in utero. Following the ban of DES in 1979, CCEA rarely occurs in young women, but still remains a ch...

  20. Pyomyositis uden feber hos 12-årig pige

    DEFF Research Database (Denmark)

    Nielsen, Mathilde Maagaard; Hindsø, Klaus; Wislander, Steen Bo;

    2009-01-01

    Bacterial pyomyositis is generally found in tropical countries. This case report presents pyomyositis in a 12-year-old girl who was admitted without fever to the paediatric department. The only symptom was pain in the left hip. Staphylococcus aureus was cultured from the blood on day 4. Magnetic ...

  1. Pituitær apopleksi hos en ung kvinde

    DEFF Research Database (Denmark)

    Lewis, Anna; Jarløv, Anne Elisabeth; Holm, Kirsten

    2014-01-01

    Pituitary apoplexy occurs when a preexisting pituitary adenoma undergoes acute haemorrhage, infarct or both. The patho-genesis is not fully understood but macroadenomas and prolactinomas have been reported as being predisposed to apoplexy. Only a few cases are described in the paediatric population...

  2. Det udstødtes poesi hos Sara Stridsberg

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2014-01-01

    Det synes at være et gennemgående projekt i Sara Stridsbergs forfatterskab at genoprejse en række upopulære, eller i hvert fald tvivlsomme og angribelige, kvindeskikkelser – hvad enten vi taler om historiske personer eller fiktive karakterer: Sally Bauer, Valerie Solanas, Medea, Lolita. Artiklen...

  3. Progredierende muskelsvind hos en tiårig pige

    DEFF Research Database (Denmark)

    Flugt, Anette; Balslev, Thomas; Christensen, Mogens Fjord

    2008-01-01

    Chronic inflammatory demyelinating polyneuropathy, CIDP, is a rare differential diagnosis to the hereditary myopathies but because it can be treated effectively it is important to consider. A ten-year-old girl's proximal muscle groups debilitated progressively, and in four months she lost the abi...... the ability to walk. Stretch reflexes were absent, creatine kinase low and spinal protein elevated. Muscle biopsy showed demyelinating atrophy. CIDP was diagnosed and she was successfully treated with immunoglobulin. Udgivelsesdato: 2008-Feb-25......Chronic inflammatory demyelinating polyneuropathy, CIDP, is a rare differential diagnosis to the hereditary myopathies but because it can be treated effectively it is important to consider. A ten-year-old girl's proximal muscle groups debilitated progressively, and in four months she lost...

  4. Legionella pneumoni hos patienter, der er i behandling med infliximab

    DEFF Research Database (Denmark)

    Vinter, Hanne; Nielsen, Henrik Ib

    2009-01-01

    Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease a...... and psoriasis, respectively. We conclude that legionella infections are probably more frequent in patients receiving immunosuppressive therapy with tumour necrosis factor-alfa inhibitors than in the background population. Udgivelsesdato: 2009-Jan-19...

  5. TV-mediet lever - også hos de unge

    DEFF Research Database (Denmark)

    Bjørner, Thomas

    2009-01-01

    TV-mediet er ikke under afvikling, men snarere under udvikling med digtitalt tv og nye medieplatforme som mobiltelefonen og nettet. TV og opfattelsen heraf er dog ikke bundet til en bestemt skærm, en medieforbrugeren udvælger medieplatformen efter en bestemt kommunikationssituation, hvor forskell......TV-mediet er ikke under afvikling, men snarere under udvikling med digtitalt tv og nye medieplatforme som mobiltelefonen og nettet. TV og opfattelsen heraf er dog ikke bundet til en bestemt skærm, en medieforbrugeren udvælger medieplatformen efter en bestemt kommunikationssituation, hvor...

  6. Monteggiafrakturer hos børn kan overses

    DEFF Research Database (Denmark)

    Abood, Ahmed Abdul-Hussein; Møller-Madsen, Bjarne; Rahbek, Ole

    2015-01-01

    Monteggia fractures in children are rare fractures presenting with anterior radial head dislocation and ulnar bowing in typical cases. In adulthood, pain, instability, deformity, loss of power and range of motion in the elbow joint are experienced. Early treatment is crucial, since the prognosis...

  7. Laktatacidose som komplikation til inhalationsbehandling hos patient med astmaeksacerbation

    DEFF Research Database (Denmark)

    Ekelund, Kim; Følsgaard, Søren Lars

    2013-01-01

    We present a case of severe lactic acidosis due to exacerbation of asthma in presence of normal tissue perfusion and oxygenation in a 35-year-old woman with poorly controlled asthma. After admission, she was treated continuously with inhalation of salbutamol (a beta-agonist) resulting in lactic...... acidosis, which was misinterpreted as treatment failure. The lactic acidosis reversed on discontinuation of the inhalation therapy. Although lactic acidosis is a rare complication to inhalation of beta-agonists, it is important for the clinicians to recognize this....

  8. Forekomst af Chlamydia trachomatis hos værnepligtige

    DEFF Research Database (Denmark)

    Søgaard, P; Møller, B R; Thorsen, Poul;

    1996-01-01

    (VD) and actual symptoms of urethritis and cervicitis. EIA positive specimens were confirmed by immunofluorescent microscopy. The investigation comprised 831 men and 80 women (17-26 years). The prevalence was 5.7% (95% confidence limits 4.2-7.4%) and 15% (8-25%) for men and women, respectively (p ... among Chlamydia positive men was 6. The frequency of earlier VD was 7.5% and 10% among men and women, respectively. Treatment with tetracycline was effective, which makes control of eradication unnecessary. We conclude that genital chlamydial infection among young asymptomatic people is common...

  9. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette;

    2009-01-01

    Bisphosphonate-associated osteonecrosis of the jaw (BON) is mainly observed in patients with multiple myeloma, and to a lesser extent in breast and prostate cancer patients receiving intravenous treatment with potent bisphosphonates. The incidence of BON increases with the duration of bisphosphon......Bisphosphonate-associated osteonecrosis of the jaw (BON) is mainly observed in patients with multiple myeloma, and to a lesser extent in breast and prostate cancer patients receiving intravenous treatment with potent bisphosphonates. The incidence of BON increases with the duration...

  10. Ervervet spondylolyse hos unge idrettsutøvere : En litteraturstudie

    OpenAIRE

    Thorsheim, Grethe Eggesbø

    2011-01-01

    Abstract One of the most common conditions of low back pain in school- age athletes is spondylolysis. Spondylolysis is a stress fracture of one or both pars interarticularis and most commonly occurs in the lower lumbar spine. Sports such as gymnastic, figure skating, football, throwing sports, volleyball, handball, dancing, diving, butterfly swimming, pole vault and weightlifting etc. place children and adolescents at a higher risk for developing these overuse injuries. (10, 11, 14, 21...

  11. Alkoholdebutalderen hos 7-18-årige unge

    DEFF Research Database (Denmark)

    Wium-Andersen, Marie Kim; Wium-Andersen, Ida Kim; Becker, Ulrik;

    2009-01-01

    of an asthma study and was based on face-to-face interviews with 480 randomly chosen children and adolescents between seven and 18 years of age. Questionnaires were sent to their parents. Onset of alcohol was defined as consumption of at least one unit of alcohol. RESULTS: Age at onset of alcohol consumption...... was 13.4 years for boys and 13.9 years for girls (p = 0.020). There was a significant association between age at onset and smoking of the adolescent (hazard ratio 2.19; 95% confidence interval (CI 1.16-4.12, p = 0.015) and maternal smoking during pregnancy (hazard ratio 2.23; 95% CI 1.31-3.78, p = 0...

  12. Behandling af kroniske sygdomme hos patienter med demens

    DEFF Research Database (Denmark)

    Pedersen, Hanne; Klinkby, Kristian Skikkild; Waldorff, Frans Borch

    2017-01-01

    , polypharmacy and chronic pain. Ongoing goal setting is important, and advance care planning is recommended. In general, comorbidity must be carefully and holistic assessed and managed according to each patient's general status of health and stage of dementia. As the dementia develops, focus should primarily...

  13. Testosteronsubstitutionsbehandling af hypogonadisme hos mænd med prostatacancer

    DEFF Research Database (Denmark)

    Fuglesang Jensen, Christian S.; Fode, Mikkel; Østergren, Peter

    2017-01-01

    Hypogonadism and prostate cancer (PCa) often coincide with increasing age. Recent reviews have found no evidence to suggest an increased risk of developing PCa with testosterone replacement therapy (TRT). The same lack of PCa risk is found in studies looking at men receiving TRT after radical...

  14. Monteggiafrakturer hos børn kan overses

    DEFF Research Database (Denmark)

    Abood, Ahmed Abdul-Hussein; Møller-Madsen, Bjarne; Rahbek, Ole

    2015-01-01

    Monteggia fractures in children are rare fractures presenting with anterior radial head dislocation and ulnar bowing in typical cases. In adulthood, pain, instability, deformity, loss of power and range of motion in the elbow joint are experienced. Early treatment is crucial, since the prognosis...... is depending on the time delay from injury to treatment. Full forearm X-rays including the elbow joint in two perpendicular projections are highly recommended in order to achieve an exact diagnosis without delay....

  15. Hjertetamponade hos et praematurt barn med perkutant anlagt centralt venekateter

    DEFF Research Database (Denmark)

    Callesen, Michael T; Nielsen, Peter Ehlert

    2008-01-01

    We report a case of a premature girl born with a gestational age of 26 weeks who developed cardiac tamponade after displacement of a peripheral inserted central catheter. She recovered completely after an acutely performed pericardiocentesis. The pericardial fluid was consistent with parental...

  16. Forekomst af alkohol, narkotika og medicin hos bilister

    DEFF Research Database (Denmark)

    Bernhoft, Inger Marie

    2011-01-01

    Inden for rammerne af det fælles-europæiske forskningsprojekt DRUID (DRiving Under the Influence of Drugs, alcohol and medicines) er forekomsten af alkohol og/eller andre stoffer blevet undersøgt i et stort antal europæiske lande, bl.a. i Danmark....

  17. Field cancerization i ansigtet hos en ung kvindelig svejser

    DEFF Research Database (Denmark)

    Kristensen, Rasmus Nygård; Sørensen, Jens Ahm

    2015-01-01

    Welding generates ultraviolet radiation and has been suggested to cause skin cancer. However, it remains questionable whether welding is in fact causally associated with the development of skin cancer. We report on a 44-year-old female with ten years occupational experience as a welder, who devel...

  18. Hvordan diagnosticerer man astma hos børn?

    DEFF Research Database (Denmark)

    Hermann, Christian

    1997-01-01

    Astma og astmatisk bronkit har ens symptomatologi og behandling og kan med vore dages effektive og bivirkningssvage medicin selv i de lettere grader behandles. Symptomerne kender vi i praksis fra op mod 1/3 af småbørnene, kunsten består i at stille behandlingsindikationen. Der opridses overvejend...... at nødvendig rutine og erfaring heri kun kan opnås ved i dagligdagen at turde tage ansvaret for at stille diagnosen og behandle. Udgivelsesdato: 1997...

  19. Seksuelle dysfunktioner hos maend, der er behandlet for testikelkraeft

    DEFF Research Database (Denmark)

    Rosendal, Susanne; Kristensen, Ellids; Giraldi, Annamaria G E

    2007-01-01

    articles. During treatment, approximately 1/3 of patients experience one or more sexual dysfunctions. Only retroperitodineal surgery is significantly correlated with a specific sexual dysfunction, which is loss of ejaculation. Psychosexual causes seem to be important in the understanding of sexual...... dysfunctions in the aftermath of testicular-cancer treatment. Udgivelsesdato: 2007-Nov-12...

  20. Case01: BIM hos mindre arkitektrådgiver

    DEFF Research Database (Denmark)

    Vestergaard, Flemming; Karlshøj, Jan; Hauch, Peter;

    Casen beskriver et IKT-koncept, hvor en hovedrådgiver, en mindre arkitektvirksomhed specialiseret i renovering og ombygning af mindre boligprojekter, anvender en modelbaseret arbejdsmetode i tre hovedleverancer for tegnestuen: et dispositionsplanforslag, et forprojekt/myndighedsprojekt og et ho-v...

  1. Dannelsen af en psykologisk og videnskabelig habitus hos psykologistuderende

    DEFF Research Database (Denmark)

    Feilberg, Casper

    grundlæggende ontologiske, epistemologiske, etiske og metodologiske spørgsmål af betydning for afhandlingens problemstilling og den teoretiske begribelse af den. Det sker ved at italesætte en eksistentiel fænomenologi baseret på Merleau-Ponty, Heidegger, Gadamer og Ricoeurs arbejde, og ved at fremhæve...... kvalitativ metodologi, med vægt på sagen selv som et fælles tredje (virkelighedsforankring), gennemskuelighed og eksemplarisk beskrivelse, samt et forudgribende forskningsdesign med bl.a. ekspliciterede forudantagelser. Det er sket ved både at trække på fænomenologer som Keller, Heidegger, Gadamer og Ricoeur......) at fremhæve den hermeneutiske cirkels vekslen mellem spørgsmål og svar, mellem forudantagelser og en revision af disse i lyset af de empiriske observationer og resultater, som en cyklisk proces mod en bedre forståelse af sagen (Gadamer), og ved 2) at forstå al fænomenologisk forskning som nødvendigvis...

  2. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    of bisphosphonate therapy and with the potency of the used bisphosphonate. BON usually develops after tooth extraction or other oral surgery, and has proven difficult to treat. Optimal dental hygiene should be ensured prior to treatment initiation where possible, and once bisphosphonate treatment is instituted......, oral surgery should be avoided if possible. Udgivelsesdato: 2009-Jan-5...

  3. Seksuel dysfunktion er hyppig hos patientermed analfistler og analfissurer

    DEFF Research Database (Denmark)

    Broholm Andersen, Malene; Møller, Henrik; Gögenur, Ismail

    2015-01-01

    Anal fistulas and fissures are frequent disorders. Affected patients may have significant psychosocial and sexual dysfunction. A few studies have investigated patients with anal fissures and fistulas with regard to sexual dysfunction. These studies showed a significant degree of sexual dysfunction...

  4. Biofilter odour reduction level, measurements; Luktreduceringsgrad hos biofilter, faeltmaetningar

    Energy Technology Data Exchange (ETDEWEB)

    Arrhenius, Karine; Rosell, Lars; Tsetsilas, Sakis (SP, Boraas (Sweden)); Loevenklev, Maria; Blomqvist, Marie; Hall, Gunnar; Sverken, Anna; Widen, Helene (SIK, Goeteborg (Sweden)); Holmgren, Magnus Andreas (Vattenfall Power Consultants (Sweden))

    2010-07-01

    Biofilter is today the most common odour reduction method for biological treatment. A biofilter consists of a bed of organic material often made of compost together with another material which increases the porosity of the bed. Microorganisms in the compost use odorous compounds as nutrient by decomposing them. Resulting products are mainly carbon dioxide and water, mineral salts, other organic compounds and more microorganisms. In this project, seven biofilters implemented in Sweden have been tested in order to describe their status and function. A number of physical, chemical, microbiological and odour related parameters have be measured in the pipe which leads to the biofilter as well as on the surface of the biofilter in order to determine biofilters status and their effectiveness. Values from plants have been compared to published optimal values for each parameter. The goal of the project is to optimize biofilters function och prevent risks for performance disturbances. Results from the project can also be used as reference for plants which are planning process modifications as an increase of waste to be treated, substrate/material changes etc. Each plant has been visited during two days in August/September 2009. The following parameters have been measured: 1) physical parameters such as relative humidity, temperature, and pH, 2) chemical parameters such as incoming and out coming gas composition, gas composition variation with time, access to nutriments, 3) microbiological parameters such as the total number of microorganisms and the dominating microflora i respective biofilter and 4) odour related parameters through an evaluation of the contribution of individual compounds to the total out coming odour and in some cases, through a evaluation by olfactometry. All these parameters have been subsequently interpreted and treated in order to evaluate the status of the biofilter: description of the biofilter, its environment, the microbiological status, which flow and load are passing through the biofilter and its effectiveness. The results show that it is common that important parameters are outside the range of recommended values. As an example, it has been found that parts of the biofilters can be either too wet or too dry. The water content of the biofilter is known to be one of the most critical parameter to insure its correct function. In some cases, the pH was found to be very acidic which negatively influences micro organism's activity and consequently biofilters efficiency. At optimal pH, the microflora is dominated by bacteria while the growth of mould dominates at low pH. An expected lower effectiveness was found when important parameters are deviating from recommended values. At the opposite, when parameters were found to be within the recommended range of values, the efficiency was found to be higher. The project general recommendations are that all plants should introduce new routines to regularly survey the biofilters status and function. Example of routines is presented in the end of this rapport. For the plants where parameters presented high discrepancies from recommended values, the project group recommends to carry out a new evaluation when the deviating parameters have been corrected

  5. Residualurin hos patienter på en geriatrisk afdeling

    DEFF Research Database (Denmark)

    Pedersen, Hanne; Nielsen, Jeanne; Juncher, Annie Elena;

    2010-01-01

    Post Void Residual Volume (PVRV) is a known risk factor for urinary infection, incontinence and renal insufficiency. Disposing for the condition is high age, immobility, constipation, neurological and metabolic disease. The objectives of this study were to determine the prevalence and to examine...

  6. Alkohol, medicin og narkotikaforekomst hos alvorligt tilskadekomne bilister

    DEFF Research Database (Denmark)

    Bernhoft, Inger Marie; Hels, Tove; Simonsen, Kirsten Wiese;

    2012-01-01

    for cannabis (2,3 %) efterfulgt af amfetamin (1,1 %). I alt var 41,6 % af de tilskadekomne i eneuheld positive for stoffer, heraf 30 % for alkohol alene eller alkohol sammen med andre stoffer. For bilister i flerpartsuheld var i alt 19 % positive, heraf knap 9 % for alkohol alene eller alkohol sammen med andre...

  7. Warfarinresistens hos en patient med hereditær trombofili

    DEFF Research Database (Denmark)

    Haastrup, Peter; Rudbæk, Torsten; Bove, Jeppe

    2013-01-01

    We present a case report of a young man with spontaneous deep venous thrombosis. He tested positive for heterozygote factor VLeiden mutation and was treated with warfarin. However, he turned out to be resistant to warfarin, and another venous thrombosis occurred during the insufficient treatment...

  8. Abdominal fedme og fedmerelaterede sygdomme hos patienter i almen praksis

    DEFF Research Database (Denmark)

    Haugan, Ketil; Rost, Dan; Knudsen, Nils;

    2010-01-01

    Abdominal obesity is associated with type 2 diabetes, cardiovascular disease, dyslipidemia and hypertension. The prevalence of abdominal obesity and its relationship with these comorbidities have not previously been examined in Danish primary care patients.......Abdominal obesity is associated with type 2 diabetes, cardiovascular disease, dyslipidemia and hypertension. The prevalence of abdominal obesity and its relationship with these comorbidities have not previously been examined in Danish primary care patients....

  9. Paraneoplastisk pancytopeni hos en patient med uerkendt lungecancer

    DEFF Research Database (Denmark)

    Hansen, Jakob Werner; Sjö, Lene; Grønbæk, Kirsten

    2014-01-01

    % blasts, but a diagnosis of myelodysplastic syndrome (MDS) was considered. After 30 days without any chemotherapeutic treatment her peripheral blood was normalised. In the meanwhile she was diagnosed with a small cell lung cancer. In this case the MDS-like condition was caused by a paraneoplastic...

  10. Prædiktorer for rygeophør i en national repræsentativ stikprøve af voksne danskere

    DEFF Research Database (Denmark)

    Zimmermann, Esther; Ekholm, Ola; Juel, Knud

    2006-01-01

    INTRODUCTION: Smoking is the largest modifiable risk factor for early death in Denmark, and reduction of the number of smokers is a high-priority health goal. The aim of this study was to investigate the importance of tobacco consumption and social position on smoking cessation in a representative...... increased with the number of years of education, for example smokers with at least 15 years of education were more likely to quit smoking than those with 10 or fewer years of education (OR 3.48; CI 2.07-5.87). CONCLUSION: As expected, the amount of tobacco consumption influenced smoking cessation, since...... consumption is associated with nicotine dependence, which makes quitting difficult. The significance of education on smoking cessation may reflect the degree of knowledge of harmful effects of smoking. Further, people with less education more often work in environments where smoking is accepted. Our results...

  11. Prædiktorer for rygeophør i en national repræsentativ stikprøve af voksne danskere

    DEFF Research Database (Denmark)

    Zimmermann, Esther; Ekholm, Ola; Juel, Knud

    2006-01-01

    consumption is associated with nicotine dependence, which makes quitting difficult. The significance of education on smoking cessation may reflect the degree of knowledge of harmful effects of smoking. Further, people with less education more often work in environments where smoking is accepted. Our results......INTRODUCTION: Smoking is the largest modifiable risk factor for early death in Denmark, and reduction of the number of smokers is a high-priority health goal. The aim of this study was to investigate the importance of tobacco consumption and social position on smoking cessation in a representative...... sample of the Danish population. This had not previously been done in Denmark. MATERIALS AND METHODS: The data were derived from the Danish Health and Morbidity Surveys of 1994 and 2000. The study population consisted of persons between 25 and 64 years of age who smoked in 1994 and who were re...

  12. Värderelevansen hos goodwill : En studie av värderelevansen hos finansiell information på den svenska marknaden

    OpenAIRE

    2009-01-01

    Finansiell information är att anses som värderelevant om den kan användas av intressenter i deras värderingsbeslut. Ett värderelevant tal bör således påverka ett företags marknadsvärde. Utifrån Easton och Harris (1991) avkastningsmodell undersöker vi relationen mellan resultat och avkastning före (2001-2004) och efter (2005-2008) införandet av IFRS/IAS-förordningen. Vi utvecklar avkastningsmodellen genom att bryta ut minskningen av goodwillpostens värde från resultatet för att på så sätt unde...

  13. Blodtrykket hos 14-15 årige skoleelever. Skolelaegers undersøgelse af blodtrykket hos 14- og 15-årige skoleelever i Vejle Amt

    DEFF Research Database (Denmark)

    Hansen, G L; Høst, A H; Laetgaard, J;

    1991-01-01

    % fractile, further investigation and advice about risk factors are recommended. The 95% fractile for boys was 144/84 mmHg and 138/88 mmHg for girls. The influence of pubertal development and body-weight on the blood pressure are reviewed. Screening in connection with health examination in the ninth form...

  14. Cowdens syndrom diagnosticeret hos patienter med store hoveder, falske vorter og struma

    DEFF Research Database (Denmark)

    Skytte, Anne-Bine; Bojesen, Anders; Bygum, Anette

    2014-01-01

    Cowden syndrome is a rare autosomal dominant syndrome with a predisposition to cancer. We present a case of Cowden syndrome in a mother and her son, who were diagnosed with palmoplantar hyperkeratosis, macrocephaly and goitre. Early diagnosis is a challenge as the patients present with a variety...

  15. Stress og udbrændthed hos alment praktiserende læger er stigende

    DEFF Research Database (Denmark)

    Pedersen, Anette Fischer; Andersen, Christina Maar; Olesen, Frede;

    2014-01-01

    Udbrændthed kommer ofte til udtryk ved følelsesmæssig udmattelse, kynisme og reduceret personligt jobudbytte. Tilstanden skyldes langvarig arbejdsbelastning i kombination med særlige personlighedstræk. Nye danske tal viser, at flere og flere danske praktiserende læger lider af alvorlig udbrændthed...

  16. Generel populationsscreening af mentalt helbred hos småbørn

    DEFF Research Database (Denmark)

    Ammitzbøll, Janni; Skovgaard, Anne Mette; Kreiner, Svend

    Hovedstadsområdet. Børnene er undersøgt i alderen 9-10 måneder, af deres sædvanlige sundhedsplejerske. Resultater fra grafisk loglineære Rasch analyser viser at PUF er unidimensionalt, uden differentiel item funktion i forhold til børnenes køn, alder og apgar score. Desuden findes cut-point for psyko...

  17. Udredning og behandling af osteoporose hos patienter med prostatacancer uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L;

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostate cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  18. Indikationer for anvendelse af PET eller PET/CT hos patienter med brystkræft

    DEFF Research Database (Denmark)

    Bernsdorf, Mogens; Graff, Jesper

    2011-01-01

    PET and PET/CT, using 18F-fluoro-2-deoxy-D-glucose, are not suited for primary diagnostics of small tumours or lymph node metastases to the axilla. In return, the method has a high sensitivity and specificity regarding the detection of loco-regional recurrence and metastases to mediastinal lymph...... nodes, bones, liver and lungs. Whether the method can replace the conventional evaluation or be a supplement if conventional evaluation is non-conclusive, remains unresolved. PET/CT has a clear advantage compared to PET alone and will probably find increasing use in the treatment planning and evaluation...... of patients with breast cancer....

  19. Omfalitis med fatal udgang hos en nyfødt dreng

    DEFF Research Database (Denmark)

    Debes, Nanette M M Mol; Dahl, Marianne; Jonsbo, Finn

    2008-01-01

    Omphalitis is a serious condition with important morbidity and mortality, especially in developing countries. The most commonly involved micro-organisms are Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. We describe a Danish patient with cellulitis...

  20. Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

    DEFF Research Database (Denmark)

    Bergmann, Troels Korshøj; Mirza, Mansoor Raza; Andersen, Charlotte Brasch;

    Formål og baggrund: Paclitaxel (Taxol®) er et kemoterapeutikum der bruges til behandling af bl.a æggestokkræft. Paclitaxel doseres individuelt (175mg/m2) men alligevel er der klinisk betydende variation i forekomsten af bivirkninger (neurotoksicitet, kvalme/opkast, knoglemarvspåvirkning m...

  1. Aluminiumallergi og granulomer som følge af vaccination hos børn

    DEFF Research Database (Denmark)

    Andersen, Rosa Marie Ø; Zachariae, Claus; Johansen, Jeanne Duus

    2015-01-01

    Vaccination with aluminium-adsorbed vaccines can induce aluminium allergy with persistent itching subcutaneous nodules at the injection site – vaccination granulomas. In this article we give an overview of childhood aluminium-adsorbed vaccines available in Denmark. Through literature studies we...... examine the incidence, the symptoms and the prognosis for the vaccination granulomas and the allergy. Finally we discuss the status in Denmark....

  2. Aluminiumallergi og granulomer som følge af vaccination hos børn

    DEFF Research Database (Denmark)

    Andersen, Rosa Marie O; Zachariae, Claus; Johansen, Jeanne Duus

    2014-01-01

    Vaccination with aluminium-adsorbed vaccines can induce aluminium allergy with persistent itching subcutaneous nodules at the injection site - vaccination granulomas. In this article we give an overview of childhood aluminium-adsorbed vaccines available in Denmark. Through literature studies we...... examine the incidence, the symptoms and the prognosis for the vaccination granulomas and the allergy. Finally we discuss the status in Denmark....

  3. Genoptraeden af kernikterus hos nyfødte børn i Danmark

    DEFF Research Database (Denmark)

    Bjerre, Jesper V.; Ebbesen, Finn

    2006-01-01

    . The maximum plasma total bilirubin concentration was 531-745 mol/l. The aetiology was determined in two infants: spherocytosis and galactosaemia. Most likely, ABO blood type immunization was the reason in four cases. In two cases, the aetiology was unknown. Seven infants had symptoms of chronic bilirubin...

  4. Inkomplet Kawasakis syndrom med koronaraneurisme hos et spædbarn

    DEFF Research Database (Denmark)

    Vinding, Rebecca Kofod; Debes, Nanette Mol; Stantchev, Hristo

    2014-01-01

    We report a four-month-old boy with incomplete Kawasaki syndrome. He developed a coronary artery aneurysm. Incomplete Kawasaki syndrome is rare in Denmark, and only reported in five patient cases in the past 25 years. It is difficult to diagnose Kawasaki disease; early diagnosis and treatment...... reduces the risk for cardiac sequel. In lack of diagnostic test, we recommend that the algorithm from the American Heart Association to diagnose incomplete Kawasaki is implemented in Denmark. The algorithm is based on classic clinical features, echocardiography and laboratory findings....

  5. Juvenilt gigant fibroadenom i brystet hos en tiårig pige

    DEFF Research Database (Denmark)

    Hasanbegovic, Emir; Talman, Maj-Lis Møller; Hjalgrim, Lisa Lyngsie

    2014-01-01

    A rapidly growing mass in the breast may be stressful for both parents and child as the suspicion of malignancy arises. The purpose of this case report is to draw attention to the fact that most emerging lesions of the breast in girls during puberty are benign. This case report presents a ten...

  6. Granulomatøs perioral dermatitis i barnealderen hos et adoptivbarn fra Madagaskar

    DEFF Research Database (Denmark)

    Mørtz, Charlotte Gotthard; Deleuran, Mette Søndergaard

    2008-01-01

    A case of childhood granulomatous perioral dermatitis (CGPD)/facial Afro-Caribbean childhood eruption (FACE) in a three year old boy from Madagascar is described. This disorder occurs predominantly in black children until puberty. It is a relatively uncommon condition of unknown aetiology...

  7. Forekomst af nylig sygdom hos danske børn i 1994 og 2000

    DEFF Research Database (Denmark)

    Nielsen, Anne M; Koefoed, Birgitte Gade; Møller, Ralf

    2006-01-01

    in the January-March quarter: 18.9%. The specific illness rates were: cold/sore throat: 4.5%; fever/influenza: 3.0%; gastrointestinal infection: 1.9%; middle ear infection: 1.3%, lower respiratory infection/asthma: 1.1%; skin disease: 0.6%; conjunctivitis: 0.4%; headache: 0.4%; injury: 0.3%; other: 0...

  8. Aclidinium bromid forbedrer lungefunktionen og reducerer dyspnø hos patienter med KOL

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2014-01-01

    Long-acting bronchodilators are central for treatment of COPD. This short review provides an overview of studies evaluating the efficacy of aclidinium bromide, a long-acting anticholinergic bronchodilator, for the treatment of COPD. Twice-daily dosing of aclidinium leads to clinically important...

  9. Det tidlige sprog hos børn med autisme - en afgørende udviklingsfaktor

    DEFF Research Database (Denmark)

    Brynskov, Cecilia; Eigsti, Inge-Marie

    2010-01-01

    bidrage til teorier om normaludviklingen. Denne artikel fokuserer på en afgørende faktor for prognosen ved autisme: den tidlige sprogudvikling. De tidlige sprogfærdigheder er en afgørende prædiktor for senere fungeren, såvel på kort som på langt sigt. Højtfungerende autisme (HFA) og Aspergers syndrom (AS...

  10. Recidiverende halscellulitis hos nyfødt forårsaget af gruppe B-streptokokker

    DEFF Research Database (Denmark)

    Rasmussen, Annett Helleskov; Fenger-Grøn, Jesper

    2011-01-01

    Group B streptococci are an important cause of neonatal infection, and cellulitis is rarely found to be the clinical manifestation. In the present case a premature boy developed cellulitis and antibiotic sensitive group B streptococci were detected in blood culture. Despite pertinent treatment...... for 14 days he developed two relapses. At last antibiotic treatment was continued for a period of six weeks with no further relapse. To our knowledge no cases of relapse of neonatal group B streptococcal cellulitis in spite of recommended dose and duration of antibiotic treatment have been published...

  11. Infektioner relateret til centralt venekateter hos børn med maligne lidelser

    DEFF Research Database (Denmark)

    Handrup, Mette Møller; Møller, Jens Kjølseth; Schrøder, Henrik

    2011-01-01

    Central venous catheters (CVC) are an essential part of the treatment of children with haematological and oncological diseases. Unfortunately, CVC also represent a major risk factor of bloodstream infections. Catheter-related bloodstream infections (CRBSI) in children are often diagnosed based on...

  12. Nonoperativ behandling af alvorlige stumpe pancreaslæsioner hos børn

    DEFF Research Database (Denmark)

    Penninga, Luit; Hillingsø, Jens

    2011-01-01

    Diagnosis and treatment of pancreatic trauma in children is challenging. Grade I and II lesions of the pancreas (Organ Injury Scale of the American Association of Trauma) are generally treated non-operatively. However, the optimal treatment of pancreatic lesions with involvement of the pancreatic...

  13. Lejringsbetingede skæve hoveder hos spædbørn kan forebygges

    DEFF Research Database (Denmark)

    Knudsen, Birgit; Christensen, Karen; Baagøe, Susanne;

    2011-01-01

    The prevalence of positional plagiocephaly is increasing. A systematic database search (Cochrane, MEDLINE, Embase, Cinahl and PEDro), critical appraisal and systematic evaluation of the quality of 14 selected studies show that the following are certain risk factors for the development of position...

  14. Tåtourniquetsyndrom hos barn på tre måneder

    DEFF Research Database (Denmark)

    Monrad, Rikke Nygaard; Rytter, Søren

    2011-01-01

    Toe tourniquet syndrome is a rare condition in which a hair or thread becomes tightly wrapped around an appendage, which causes ischaemic strangulation. We present a three month-old infant with strangulation of one toe to direct attention to this condition. Prompt recognition and complete removal...

  15. Monstrøse folkeslag hos Plinius den Ældre

    DEFF Research Database (Denmark)

    Isager, Jacob

    2011-01-01

    Afsnittet om monstrøse folkeslag i den Ældre Plinius' Naturhistorie er den eneste tekst fra den græsk-romerske oldtid, der giver en oversigt over dette specielle emne, som flere nu tabte antikke forfattere har skrevet om. De "plinianske folkeracer" har fået en kanonisk status i eftertiden både i ...

  16. Fatal neutropen enterokolitis hos en patient i kemoterapi med kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Kongsted, Per; Sheikh, Kiran; Mouritsen, Lene Sonne;

    2015-01-01

    and abdominal pain. Treatment is not clearly defined. We present a fatal case of NE in a patient with prostate cancer treated with first-line chemotherapy, docetaxel 75 mg/m2 every three weeks and prednisolone 5 mg × 2 daily. The post-mortem examination confirmed NE with prostate cancer cells in bowel wall....

  17. Gode muligheder for høj velfærd hos mink

    DEFF Research Database (Denmark)

    Møller, Steen Henrik

    2010-01-01

    Mink kan have god velfærd i moderne pelsproduktion. Men gruppeindhusning er problematisk, og der er behov for at overvåge, dokumentere og udvikle velfærden. Det mener forskere ved Aarhus og Københavns universiteter, som arbejder med husdyr og husdyrvelfærd.......Mink kan have god velfærd i moderne pelsproduktion. Men gruppeindhusning er problematisk, og der er behov for at overvåge, dokumentere og udvikle velfærden. Det mener forskere ved Aarhus og Københavns universiteter, som arbejder med husdyr og husdyrvelfærd....

  18. Tobaksrygning og risiko for hoftebrud hos maend og kvinder. Resultater fra Hovedstadens Center for Prospektive Befolkningsstudier

    DEFF Research Database (Denmark)

    Høidrup, S; Prescott, E I; Sørensen, T I

    2001-01-01

    smokers had a relative risk of hip fracture of 1.36 (1.12-1.65) and male smoked 1.59 (1.04-2.43) relative to those who have never smoked. In both sexes, the relative risk of hip fracture gradually increased with current and accumulated tobacco consumption. A test for interaction between gender and smoking......INTRODUCTION: In the present population-based cohort study, we prospectively determined the influence of current, previous, and cumulative smoking history on the risk of hip fracture in men and women and addressed the issue of possible gender difference in susceptibility to tobacco smoking...... habits was insignificant. Men who stopped smoking for more than five years had a lower risk of hip fracture than men who currently smoked, whereas no such risk reduction was seen in female ex-smokers. CONCLUSION: Tobacco smoking is an independent risk factor for hip fracture in men and women...

  19. Inkomplet Kawasakis syndrom med koronaraneurisme hos et spædbarn

    DEFF Research Database (Denmark)

    Vinding, Rebecca Kofod; Debes, Nanette Mol; Stantchev, Hristo

    2014-01-01

    We report a four-month-old boy with incomplete Kawasaki syndrome. He developed a coronary artery aneurysm. Incomplete Kawasaki syndrome is rare in Denmark, and only reported in five patient cases in the past 25 years. It is difficult to diagnose Kawasaki disease; early diagnosis and treatment...... reduces the risk for cardiac sequel. In lack of diagnostic test, we recommend that the algorithm from the American Heart Association to diagnose incomplete Kawasaki is implemented in Denmark. The algorithm is based on classic clinical features, echocardiography and laboratory findings....

  20. Virkning af propylenglykol på fedtmobilisering hos fede nykælvere

    DEFF Research Database (Denmark)

    Bjerre-Harpøth, Vibeke; Storm, Adam Christian; Larsen, Torben;

    2015-01-01

    metabolismen, som resulterede i en reduceret risiko for ketose. Tildeling af propylenglykol til køer i risiko for lipid-relatede sygdomme forekommer således at være gavnligt. Perspektivet for tildeling af propylenglykol i få uger efter kælvning synes at være en to-trin adaption til laktation, hvor lavpunktet...

  1. Benign paroksysmal positionel vertigo kan opstå efter hovedtraumer hos børn

    DEFF Research Database (Denmark)

    Nørgaard, Maria Schøler; Rokkjær, Malene Sine; Berg, Jette

    2015-01-01

    We present an eight-year-old boy with benign paroxysmal positional vertigo (BPPV) after a head trauma, successfully treated with Epley's manoeuvre. BPPV is a common cause of vestibular vertigo in adults, but it is rarely seen in children. Diagnostic work-up is challenging as children often lack...

  2. Cerebral hæmoragi hos 12-årig pige

    DEFF Research Database (Denmark)

    Søndergaard, Mia; Grunnet, Sarah; Born, Alfred Peter

    2012-01-01

    A 12-year-old girl with an upper respiratory infection deteriorated suddenly with a severe headache and declining level of consciousness, and was brought to the ER on suspicion of meningitis. On arrival, the girl had a Glascow Coma Scale score of 6 and a dilated pupil that was not reactive to light...

  3. Svær akut underernæring hos børn

    DEFF Research Database (Denmark)

    Fabiansen, Christian; Christensen, Vibeke Brix; Eklund, Martin

    2010-01-01

    Severe acute malnutrition (SAM) affects approx. 19 million children below five years of age in low and middle income countries. Both shortage and low quality of foods are important determinants of SAM. With the development of special ready-to-use foods and by using simple treatment protocols, it ......, it is now possible to treat SAM successfully outside hospitals and treatment centers thereby reducing the case-fatality rate. However, only a small percentage of children with SAM have access to correct treatment....

  4. Forekomst af indvoldsorm hos hunde på Færøerne

    DEFF Research Database (Denmark)

    Petersen, Signar; Joensen, Kristina Dahl; Monrad, Jesper

    2008-01-01

    af den koprologiske undersøgelse fandtes 18 af hundene (7,9 %) inficeret med en eller flere helmintharter, idet 4,0 % (n=9) var inficeret med Toxocara canis, 2,6 % (n=6) med Taenia spp., 0,9 % (n=2) med Trichuris vulpis, 0,4 % (n=1, en hund importeret , 0,4 % (n=1, en hund importeretfra Danmark 7 år...

  5. Svin som smittekilde til infektioner med methicillinresistente Staphylococcus aureus hos mennesker

    DEFF Research Database (Denmark)

    Ruhlmann, Christina H; Kolmos, Hans Jørn J; Kristiansen, Jette E

    2008-01-01

    occupational contact with pigs. One infection presented as a severe surgical wound infection, following knee surgery, the other as a superficial ear lobe infection. Both MRSA strains were multiresistant, sequence type 398, Spa-type t034, and Panton-Valentine leukocidin-encoding gene negative. Udgivelsesdato...

  6. Svaer vitamin B12-mangel hos spaedbørn brysternaeret af veganere

    DEFF Research Database (Denmark)

    Roed, Casper; Skovby, Flemming; Lund, Allan Meldgaard

    2009-01-01

    with cyanocobalamin was instituted with remission of symptoms. Since infants risk irreversible neurologic damage following severe vitamin B12 deficiency, early diagnosis and treatment are mandatory. Vegan and vegetarian women should take vitamin B12 supplementation during the pregnancy and nursing period...

  7. Superheater corrosion in kraft recovery boilers; Korrosion hos oeverhettare i sodapannor. En oeversikt och diskussion

    Energy Technology Data Exchange (ETDEWEB)

    Bruno, F. [AaF-IPK, Stockholm (Sweden)

    1997-02-01

    Corrosion seems to be the most essential factor limiting the life and the availability of kraft recovery boilers. The steam temperature from the kraft recovery boiler has, seen from the view of electricity production and steam turbine operation, traditionally been kept moderate, especially in comparison with steam data from normal utility power plants. So the corrosion of the superheaters has been more a limitation for the temperature of the steam produced by the boiler than a life length limitation. Both the pressure and the temperature of the steam are limited by corrosion. The temperature of the boiling water, and hence the pressure, is limited by the corrosion in the lower furnace. The temperature of the steam is limited by the corrosion in the superheater. Kraft boiler superheater corrosion is here governed not only by the boiler design, but more by the mill chemistry and boiler operation practice. This report discusses the formation and the properties of the deposits and their relation to boiler operation and the corrosion of the superheater tube material. We have tried to understand the corrosion in the kraft boiler superheaters better by comparing with the experience from the utility boilers. 86 refs, 79 figs

  8. Effekten af perkutan koronar intervention hos kvinder med iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Holmvang, Lene; Mickley, Hans

    2007-01-01

    syndromes there is no evidence of gender differences regarding the benefit of primary PCI for ST-segment elevation myocardial infarction. However, several trials of unstable angina and non-ST-segment elevation myocardial infarction indicate that compared with men, women do not get the same benefit...

  9. Hvordan etablere en sunn livsstil hos en overvektig inaktiv kvinne med psykisk utviklingshemning

    Directory of Open Access Journals (Sweden)

    Christine Tørris

    2015-06-01

    Full Text Available How to establish a healthy lifestyle in an overweight, inactive woman with an intellectual disabilityOverweight and obesity are associated with increased health risks and shortened life span. The prevalence of overweight and obesity is increasing, and a higher prevalence of obesity has been observed in persons with intellectual disability than in the general population. In this study, we want to establish a healthy lifestyle with a healthy diet and increased physical activity in an obese, inactive women with intellectual disability. Using interventions based on applied behavioural analysis, the women have established new habits in terms of diet and increased physical activity. The number of hours with physical activity per week has doubled, and both weight and waist circumference decreased during the eight weeks of the study. She maintained her new healthy lifestyle, after the study. More research is needed in interventions that can help reduce obesity in persons with intellectual disability.

  10. Udredning og behandling af osteoporose hos patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Brask-Lindemann, Dorte; Vestbo, Jørgen;

    2012-01-01

    Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease.......Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease....

  11. Osteoporoseprofylakse hos patienter indlagt med hoftenaere lavenergifrakturer på ortopaedkirurgisk afdeling

    DEFF Research Database (Denmark)

    Brock-Jacobsen, Iben; Wiboe, Linda; Mogensen, Christian B;

    2002-01-01

    The aim of this study was to investigate the following in patients treated for low energy hip fractures: 1) whether they were using osteoporosis preventative therapy before admission to hospital; 2) whether therapy was initiated before discharge from hospital; 3) the therapy used; and 4) whether...... they were referred for follow-up treatment for osteoporosis after discharge....

  12. Karotinaemi hos patient med excessivt betakarotinfødeindtag og dysreguleret diabetes mellitus

    DEFF Research Database (Denmark)

    Mikkelsen, Carsten Sauer; Mikkelsen, Dorthe Bisgaard; Lindegaard, Hanne Merete

    2009-01-01

    A case of carotinaemia in a patient with excessive beta-carotene food-intake, diabetes mellitus and physiological amenorrhea is reported. The patient developed yellow discolouration in the palms and the soles of her feet. Blood samples showed a significantly increased lever of serum beta......-carotene, but normal vitamine A value and liver enzymes. The patient reported an excessive intake of carrots (approximately 1 kg per day). The status of physiological amenorrhoea and dysregulated diabetes mellitus may have deteriorated the yellow discolouration of the skin. Udgivelsesdato: 2009-Jan-26...

  13. Koronararteriecalciumscore ved hjertecomputertomografi øger den prognostiske information hos udvalgte personer

    DEFF Research Database (Denmark)

    Rasmussen, Thomas; Zacho, Mette; Kourmaeva, Daria

    2011-01-01

    Cardiovascular disease is the leading cause of death in the western countries. Conventional risk evaluation of asymptomatic individuals is unfortunately inaccurate. There is a need for better diagnostic tools to identify persons, who will benefit from intensified preventive treatment. Coronary...... artery calcium score (CACS) measured by multi-slice CT scan contributes significantly to risk stratification especially in persons with intermediate risk assessed by conventional risk analysis. A CACS-guided preventive intervention strategy seems appealing to reduce mortality due to cardiovascular...

  14. Selvmord hos patienter med apopleksi. En epidemiologisk undersøgelse

    DEFF Research Database (Denmark)

    Stenager, E N; Madsen, C; Stenager, E;

    1999-01-01

    patients was increased compared to the background population, i.e. the total population of the County of Funen. The patients were followed for causes of death until end of 1989. Standard Mortality Ratios for suicide standardized for age and sex in male and female stroke patients were calculated. A total......The purpose of this study was, on the basis of a cohort of patients with a discharge diagnosis of stroke (ICD8 code: 430-438) diagnosed in the period 1.4.1973-31.12.1989 in a representatively selected area of Denmark (County of Funen), to estimate whether or not the risk of suicide in stroke...... of 37,869 stroke patients were included in the study, 140 committed suicide in the study period (80 females and 60 males). Standard Mortality Ratio for suicide was significantly increased for all stroke patients. For women below 49 years and from 50-59 years Standard Mortality Ratios were 1376 and 1378...

  15. Akut pankreatitis hos en 16-årig dreng efter indtag af ibuprofen

    DEFF Research Database (Denmark)

    Bruusgaard-Mouritsen, Mads Emil; Leerhøy, Bonna; Hansen, Mark Berner

    2015-01-01

    This is a case report of a 16-year-old boy with possible drug-induced pancreatitis (DIP) caused by ibuprofen. The patient had a history of psychiatric, but no somatic, disease, and he was admitted with a clinical presentation consistent with acute pancreatitis after a bolus ingestion of 10 g...... of ibuprofen in a suicidal attempt. No evidence of other causality for acute pancreatitis was identified. The patient was treated with a standard pancreatitis treatment regime and was discharged against medical advice after four days. The case represents a possible causality between ibuprofen and DIP....

  16. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    and the inability to remember were both reduced, when comparing results during active treatment to placebo. Short-term memory did not change significantly. In conclusion, our study has shown that treatment with the Ginkgo biloba extract GB-8 improves some cognitive functions in elderly patients with moderate...... of concentration, and inability to remember. Short-term memory was objectively assessed. We did not find any significant changes in either peripheral blood pressures, walking distances or the severity of leg pain. Systemic blood pressure was reduced both by placebo and GB-8. The impairment of concentration...

  17. Øget forekomst af depression hos patienter med hepatitis C-infektion

    DEFF Research Database (Denmark)

    Hjerrild, Simon; Renvillard, Signe Groth; Leutscher, Peter Derek Christian;

    2010-01-01

    The prevalence of depression is increased in patients with chronic hepatitis C virus (HCV) infection. Several aetiological mechanisms are thought to be involved, e.g. premorbid psychiatric disease, genetic disposition to affective disorders, socio-economic factors, stigmatization and possibly HCV...... neuroinfection. Evidence to support that former intravenous drug abuse increases the risk of depression is lacking. It is particularly important to diagnose and treat depression in HCV patients as it constitutes a relative contraindication to antiviral treatment and may jeopardize therapeutic outcome....

  18. Epstein-Barr-virus-associeret lymfom hos en patient med colitis ulcerosa i behandling med azathioprin

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Kiszka-Kanowitz, Marianne; Albrectsen, Jens Mørch;

    2008-01-01

    A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV-associat......A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV...

  19. Fatal hæmofagocytisk lymfohistiocytose og mononukleose hos en patient med colitis ulcerosa

    DEFF Research Database (Denmark)

    Juul Ingvardsen, Charlotte; Ballegaard, Vibe Cecilie; Homøe, Preben

    2012-01-01

    We report a case of Epstein-Barr virus primo infection with the development of lethal haemophagocytic lymphohistiocytosis (HLH) in a 22 year-old man, who was being treated with azathioprin for colitis ulcerosa. HLH is a rare, life-threatening disease, which is caused by an inappropriate activation...

  20. Ukarakteristiske symptomer hos patienter med debut af kolorektal cancer i almen praksis

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Vedsted, Peter

    2012-01-01

    symptomer, og disse omfatter fx lav blodprocent, vekslende afføring, maveproblemer, træthed og vægttab. En kommende screeningskampagne vil identificere en række af disse tumorer tidligere i forløbet, men stadig skal 75 % af alle tyktarmscancere skulle diagnosticeres vha. symptomer og den praktiserende læge...

  1. Transportproteiner som drug-targets hos Plasmodium falciparum. Nye perspektiver i behandlingen af malaria

    DEFF Research Database (Denmark)

    Ellekvist, Peter; Colding, Hanne

    2006-01-01

    The malaria parasite, Plasmodium falciparum, infects and replicates in human erythrocytes. Through the use of substrate-specific transport proteins, P. falciparum takes up nutrients from the erythrocyte's cytoplasm. The sequencing and publishing of the P. falciparum genome have made it possible...

  2. Optisk og videoassisteret laryngoskopi ved vanskelige luftveje hos børn

    DEFF Research Database (Denmark)

    Bille, Anders Bastholm; Holm-Knudsen, Rolf; Lefort, Michelle

    2012-01-01

    Despite ongoing technological advances, direct laryngoscopy still remains the golden standard for endotracheal intubation in children and infants. However, in some infants it is almost impossible to obtain a view of glottis and the vocal cords. In this paper we present an overview of the recent a...... advances in optical and video-assisted laryngoscopy in difficult paediatric airways.......Despite ongoing technological advances, direct laryngoscopy still remains the golden standard for endotracheal intubation in children and infants. However, in some infants it is almost impossible to obtain a view of glottis and the vocal cords. In this paper we present an overview of the recent...

  3. Graviditetskomplikationer hos en patient med systemisk lupus erythematosus og lupus nefritis

    DEFF Research Database (Denmark)

    Bisgaard, Helene; Jacobsen, Søren; Tvede, Niels

    2014-01-01

    A woman with systemic lupus erythematosus (SLE) and lupus nephritis had two pregnancies which both resulted in complications known to be associated with SLE, i.e. late abortion, preterm delivery and pre-eclampsia. We conclude that disease quiescence is important for a successful outcome...

  4. Suicidaladfaerd hos børn--en deskriptiv undersøgelse

    DEFF Research Database (Denmark)

    Høg, Vibeke; Isager, Torben; Skovgaard, Anne Mette

    2002-01-01

    Psychiatric illness and suicide attempts are important risk factors for suicide in young people. To what extent suicidal behaviour in childhood predicts suicidal behaviour and suicide later in life is not known, and studies concerning suicidal behaviour and psychopathology in children are limited....... The objective of the study was to describe suicidal behaviour in children referred to child psychiatric assessment concerning the frequency and characteristics of the suicidal behaviour and the psychiatric diagnoses of the children....

  5. Femoro-acetabulaer impingement: årsag til lyskesmerter og tidlig hofteslidgigt hos yngre patienter

    DEFF Research Database (Denmark)

    Jacobsen, Steffen; Winge, Søren

    2007-01-01

    In Denmark, approximately 7,000 hip joints are replaced by total hip arthroplasties annually. In 80% of the cases, the diagnosis is idiopathic end-stage osteoarthritis. Scientifically this is hardly acceptable. However, the last decade has witnessed a proliferative research in biomechanically imp...

  6. Fejldiagnostik ved vaginal skanning hos en kvinde, der var gravid efter hormonel follikelstimulation

    DEFF Research Database (Denmark)

    Al-Najami, Issam; Salomon, Søren

    2014-01-01

    We present the case of a 21-year-old woman who developed a simultaneous extra- and intrauterine pregnancy after hormonal induction of ovulation. The case shows a delay in the detection, relying on usual measures as vaginal ultrasound scanning, of the ectopic pregnancy resulting in peritonealia an...

  7. Psykiatriske indlaeggelser hos bybuschauffører. En prospektiv undersøgelse

    DEFF Research Database (Denmark)

    Netterstrøm, Bo; Juel, K

    1989-01-01

    . Significantly fewer admissions among bus drivers were found in the diagnostic group manic depressive psychoses, reactive conditions and for all psychiatric admissions. On the other hand, the number of admissions among bus drivers where the diagnoses of affect reactions, paranoid conditions and non......-specific psychoses were found to be significantly higher (standard morbidity ratio statistic = 217) than for Danish men. Odds-ratio for psychiatric admissions among the 2,045 bus drivers who had replied to the questionnaire in 1978 were significantly raised for the bus drivers who did not feel their work monotonous...

  8. Molekylaere mekanismer bag den immunologiske reaktion mod gluten hos patienter med cøliaki

    DEFF Research Database (Denmark)

    Nielsen, Christian; Husby, Steffen; Lillevang, Søren T

    2003-01-01

    Coeliac disease is a complex inflammatory disorder of the small intestine, induced by dietary gluten in genetically susceptible individuals. Recently, the nature of gluten-derived peptides recognized by gut-derived T cells from patients has been elucidated. It has further been established...

  9. Multiple embolier efter DC-konvertering hos en patient forbehandlet med dabigatran

    DEFF Research Database (Denmark)

    Buch, Torben Nicolai; Holm, Jakob; Munck, Lars Kristian

    2013-01-01

    A 65-year-old man, who had been treated with dabigatran for 66 days prior to electrical cardioversion, developed extensive intestinal, renal and cerebral thromboembolism five days after cardioversion. There is limited information available on the treatment of thromboembolism in patients being tre...

  10. Kvælstoffiksering hos cyanobakterier og heterotrofe bakterier i kystnære danske farvande

    DEFF Research Database (Denmark)

    Bentzon-Tilia, M.; Traving, S. J.; Mantikci, Mustafa

    organisms. In this overview, I will talk about our work in Danish estuaries with emphasis on N2fixation by heterotrophic diazotrophs. In general, we have measured N2 fixation, examined nitrogenase (nifH) gene composition by next-generation sequencing, and used real-time PCR to quantify distribution of key...... nifH genes or transcripts in situ. We examined diazotrophy over one year in two contrasting, temperate, estuarine systems (Roskilde Fjord and the Great Belt strait; Bentzon-Tilia et al. 2014). In Roskilde Fjord, N2 fixation was mainly accompanied by transcripts related to heterotrophic (e.......g. Pseudomonas sp.) and photoheterotrophic bacteria (e.g. unicellular diazotrophic cyanobacteria group A). In the Great Belt, the first of two N2 fixation peaks coincided with a similar nifH expressing community as in Roskilde Fjord, whereas the second peak was synchronous with increased nifH expression...

  11. Kompliceret influenza A (H1N1) hos gravid i andet trimester

    DEFF Research Database (Denmark)

    Ersbøll, A.S.; Hedegaard, M.; Hesselvig, A.B.

    2012-01-01

    A 27-year-old woman at 25 weeks of gestation was admitted to hospital due to bilateral pneumonia with increasing hypoxia. She was tested positive for influenza A (H1N1) and successfully treated with oral oseltamivir. Nine days after the admission pathological umbilical flows were recorded...... and an emergency caesarean was performed at 26 weeks + 2 days of gestation. The neonatal period was uncomplicated. Influenza A (H1N1) is especially dangerous in pregnant women and vaccination is important....

  12. Granulomatøs perioral dermatitis i barnealderen hos et adoptivbarn fra Madagaskar

    DEFF Research Database (Denmark)

    Mørtz, Charlotte Gotthard; Deleuran, Mette Søndergaard

    2008-01-01

    characterized by a monomorphic, papular eruption around the mouth, nose and eyes. The disorder looks like sarcoidosis, but it is benign and self-limited and not associated with any systemic manifestations. In our case we treated the patient with Elidel (pimecrolimus) with an excellent result. Udgivelsesdato...

  13. Schmallenberg virus – et nyt virus hos drøvtyggere

    DEFF Research Database (Denmark)

    Lohse, Louise

    undersøgelser på laboratoriet, blev alle prøver i en længere periode testet negative for kendte patogener, der evt. kunne tænkes at knytte sig til disse sygdomsudbrud. Efterfølgende fandt man ved sekvensanalyse på DNA/RNA oprenset fra prøvematerialet lighed med virus fra orthobunyavirusgruppen. Disse virus er...... normalt vektorbårne og er kendt som årsag til sygdom i drøvtyggere i Australien, Asien, Afrika og Mellemøsten. Det nye virus blev kaldt Schmallenberg virus (SBV) efter stedet hvor det første tilfælde blev påvist. Siden har Schmallenberg virus spredt sig og er nu påvist i får, kvæg og geder i Tyskland......, Holland, Belgien, Luxembourg, Frankrig, Spanien, Italien og Storbritannien (status april 2012). Det antages, at virus overføres med mitter og myg og inkubationstiden har fra eksperimentelle forsøg vist sig at være kort (1-4 dage). Virus cirkulerer få dage i blodet og manifesterer sig ved milde uspecifikke...

  14. Storkarsvaskulitis påvist ved PET/CT hos patient med initialt formodet cancer

    DEFF Research Database (Denmark)

    Andersen, Kim Francis; Skøt, Jens; Bülow, Jens

    2012-01-01

    Large vessel vasculitis, including giant cell arteritis and Takayasu arteritis, is traditionally diagnosed and classified according to the American College of Rheumatology criteria, which do not include findings on imaging modalities. We present a case in which non-invasive imaging with 18F......-fluorodeoxyglucose positron emission tomography/computed tomography gave essential information in the diagnostic work-up of large vessel vasculitis in a female presenting with non-specific symptoms. We discuss the role of nuclear medicine imaging in early diagnosis and follow-up of this inflammatory disease, characterized...... by granulomatous panarteritis of the aorta and its major branches....

  15. Risiko for øget sygelighed hos kvindelige idraetsudøvere

    DEFF Research Database (Denmark)

    Olesen, Anette Grønning; Clausen, Helle Vibeke; Skouby, Sven Olaf

    2010-01-01

    The female athlete triad refers to the interrelationships among energy availability, menstrual function and bone mineral density which may have clinical manifestations including eating disorders, functional hypothalamic amenorrhea and osteoporosis. The potentially irreversible consequences...

  16. Bestämning av osäkerheten hos skattningar av tyngdaccelerationen

    OpenAIRE

    Åberg, Tomas

    2000-01-01

    In this master's thesis the problem of determining the uncertainty for an estimator of an unknown parameter is considered. The case we study is the estimation of gravity using a reversible pendulum. This involves the estimation of the point where two regression lines intersect. The estimated gravity is a function the coordinates of this point. One way to determine the uncertainty of this estimator is to use bootstrap methods. In this paper three different bootstrap methods are considered. To ...

  17. Et godt sted at græde og le hos Helle Helle

    DEFF Research Database (Denmark)

    Hansen, Per Krogh

    2014-01-01

    Da Helle Helle (f. 1965) i 2010 blev indstillet af Statens Kunstfonds repræsentantskab til at modtage livsvarig kunstnerydelse, lød begrundelsen, at hun var ”en af Danmarks vigtigste fortolkere af middelklassen og den danske provins.” Og sådan er hun generelt også blevet modtaget og fortolket: Som...

  18. beta-thalassaemia major hos børn og unge i Danmark

    DEFF Research Database (Denmark)

    Jung, Anne; Main, Katharina Maria; Scheibel, Elma;

    2002-01-01

    strategy. MATERIAL AND METHODS: During 1998-99 all Danish pediatric departments were contacted for identification of children aged 0-18 years with beta-thalassemia major. Blood transfusions and chelation therapy were registered, and for Eastern Denmark clinical, endocrine, cardiac, and serologic parameters....... An earlier and more effective iron chelation therapy together with improved patient support may reduce growth disturbances and endocrine and cardiac late effects. Udgivelsesdato: 2002-Dec-2...

  19. Vilometabolism hos barn och ungdomar med Cerebral Pares : En deskriptiv korrelationsstudie

    OpenAIRE

    Karlsson, Maria; Arborén, Charlotte

    2013-01-01

    Background: Cerebral Palsy is usually divided into three subgroups: ataxic, spastic and dyskinetic, where children and adolescents can, because of misestimation in nutrition and energy intake, suffer from weight problems. Aim: To compare calculations with equations with the individual's measured RMR in the subgroups, to see if any equation is more suitable. This could be used as a tool to calculate the resting metabolism at times when it is not possible to perform clinical measurements. Metho...

  20. Idiopatisk pulmonal hæmosiderose hos en et-årig piga med Down syndrom

    DEFF Research Database (Denmark)

    Lewis, Anna Elisabeth; Høi-Hansen, Christina Engel; Buchvald, Frederik

    2014-01-01

    Idiopathic pulmonary haemosiderosis (IPH) is a rare disease. We describe a girl with Down syndrome who had no major respiratory symptoms until one year of age, where recurrent airway infections and chronic anaemia of unknown aetiology developed. At 20 months of age she had intermittent haemo...

  1. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    size, this audit suggests that long preoperative delay in patients with peptic ulcer perforation is associated with factors related to both the internal organisation of the healthcare system, the patient's pathological picture, and the quality of diagnosis and treatment given. Udgivelsesdato: 2009-Nov......INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit...... was conducted to investigate possible reasons. MATERIAL AND METHODS: All patients (n = 89) surgically treated for peptic ulcer perforation in six university hospitals in Denmark over a period of one year were included. The association between a number of predefined variables related to the internal organisation...

  2. Præsentation af symptomer i almen praksis hos patienter med cancer

    DEFF Research Database (Denmark)

    Nielsen, Tine Nørgaard; Hansen, Rikke Pilegaard; Vedsted, Peter

    2010-01-01

    and prostate cancer presented diagnosis-specific symptoms (change in bowel habits, cough and bladder dysfunction) as well as more non-specific symptoms (pain, weight loss and fatigue). The GPs interpreted the symptoms as alarm symptoms in 49%, as general symptoms in 24% and as non-cancer specific symptoms...... in 27% of the patients. CONCLUSIONS: In general practice, incident cancer patients often present with few and non-cancer specific symptoms. The fact that only half of the patients presented with alarm symptoms complicates the GPs' diagnostic work-up and the use of fast track for suspected cancer...

  3. Claudicatio intermittens--sociale aspekter hos yngre ikke-opererede patienter

    DEFF Research Database (Denmark)

    Lundvall, L; Jensen, K H; Simonsen, L

    1989-01-01

    A total of 107 patients suffering from intermittent claudication (CI) was studied after a mean observation time of 5.9 years. Thirty-one (29%) had died during the observation period. A questionnaire was sent to 76 patients and 78% replied. All patients were under 50 years of age at the first cons...

  4. Cerebral flow og intraventrikulær blødning hos premature

    OpenAIRE

    Lossius, Anne Kristine

    2009-01-01

    Intraventricular haemorrhage (IVH) is a serious complication in premature infants. This type of bleeding may lead to serious neurological sequelae or even death. IVH is prevalent in VLBW children, with an incidence of 30%. Recent research shows a significant relationship between low cerebral blood flow and IVH. The most common way to measure blood flow is to measure blood pressure. However, studies suggest that a more correct method is to measure the SVC (Superior vena cava) flow. The SV...

  5. Lichen sclerosus er også en sygdom hos børn

    DEFF Research Database (Denmark)

    Baskaramoorthy, Shailajah; Bygum, Anette

    2012-01-01

    of the girls had a classic porcelain white plaque in a figure-of-eight pattern encircling the vaginal introitus and perianal area. The other girl presented with vulvar bleeding raising a suspicion of sexual abuse. Both children were treated with potent topical steroids with an effective response.......Lichen sclerosus in children is an uncommon skin disease with a predilection for the genital region. The disease is primarily seen in prepubertal girls and postmenopausal women. We present two cases of four year-old girls referred with classical symptoms but a long diagnostic latency. One...

  6. Præoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...

  7. Udvikling af dialogisk kompetence hos børn med CI

    DEFF Research Database (Denmark)

    Dammeyer, Jesper Herup; Carstensen, Susanne; Karlshøj, Bente;

    2011-01-01

    Der er relativ god viden om børn med CI’s sproglige udvikling, hvad angår sproglyde og ord. Derimod er der i den internationale forskning kun beskrevet meget lidt om den del af den sproglige udvikling, som ligger ud over sætningsniveauet. Denne artikel beskriver nogle af de resultater, der er...... fremkommet ved et fire år langt følgestudie af tre førskolebørn med CI. Børnenes sproglige udvikling er observeret og analyseret i forhold til dialogiske kompetencer. Resultaterne peger på, at børnene udvikler gode talesproglige kompetencer i løbet af den fireårige periode, men at børnene har brug for støtte...

  8. Tarm- og blæreproblemer samt seksuel dysfunktion hos patienter med multipel sklerose

    DEFF Research Database (Denmark)

    Falck Giraldi, Laura Victoria; Sønksen, Jens; Fode, Mikkel

    2016-01-01

    Patients suffering from multiple sclerosis (MS) often experience bothersome symptoms from the gastrointestinal system and the urinary tract, and they may suffer from sexual dysfunction. These problems can diminish quality of life, and therefore it is important that they are addressed and treated...

  9. Hyperprolaktinæmi som årsag til nedsat sexlyst hos mænd

    DEFF Research Database (Denmark)

    Baltzar, Mette Thing; Anholm, Christian; Petersen, Christina Damsted

    2012-01-01

    Algorithms previously focused primarily on the testosterone level and its role when diagnosing and managing hypoactive sexual desire (HSD) in men. The importance of prolactin in male sexuality is recognized and should be taken into account when investigating more complex cases of HSD in men....

  10. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe;

    2010-01-01

    INTRODUCTION: The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need...

  11. Sproglige og studiemæssige udfordringer hos studerende med dansk som andetsprog - pilotprojekt

    DEFF Research Database (Denmark)

    Møller, Pia Hildebrand

    2015-01-01

    Denne rapport beskriver et pilotprojekt ved Rådgivnings- og støtteenheden på Aarhus Universitet. Projekt har undersøgt, hvilke sproglige og studiemæssige udfordringer, som studerende med dansk som andetsprog tilknyttet enheden, har....

  12. Effekt af trombolytisk behandling på udfaldet af tidlig arbejdstest hos patienter med akut myokardieinfarkt

    DEFF Research Database (Denmark)

    Svendsen, Jesper Hastrup; Madsen, J K; Saunamäki, K I;

    1994-01-01

    Exercise test variables, such as an impaired heart rate response, are known to be related to left ventricular function and patient prognosis following acute myocardial infarction. The present study was performed to compare exercise test variables in acute myocardial infarct patients following eit...

  13. Validitet af diagnosen urinvejsinfektion hos børn under to år

    DEFF Research Database (Denmark)

    Cortes, Dina; Birkild, G; Rasmussen, Lene;

    1999-01-01

    to study if these criteria were fulfilled in our department, which takes care of urinary tract infections in children in the county of Frederiksborg with a catchment area of about 350.000 people. From 1994-1996 a total of 60 children younger than two years of age were treated for their first suspected...

  14. Svaer bronkospasme hos et-årigt barn behandlet med halotan

    DEFF Research Database (Denmark)

    Hansen, Tom Giedsing; Pedersen, C M; Lybecker, H

    1994-01-01

    A case of severe bronchospasm in a one-year old mechanically ventilated girl which in spite of maximal conventional bronchodilatory treatment only responded to halothane inhalation is presented. The benefits and limitations of this therapy are discussed....

  15. Spiseforstyrrelse hos en 19 måneder gammel pige med komorbid mor-barn-relationsforstyrrelse

    DEFF Research Database (Denmark)

    Olsen, Anne Lise; Sigvard, Anne Mette; Skovgaard, Anne Mette

    2015-01-01

    Feeding and eating problems and weight faltering are common causes for parents contact to health services in infancy and early childhood, and 0.15% of the child population aged 0-3 years are diagnosed at hospital with an ICD-10 childhood eating disorder. We describe the clinical presentation...... of an early feeding and eating disorder in a child of basically normal health and deve-l-op-ment. The case illustrates the significance of the mother child relationship both in the putative risk mechanisms and as a key factor in the treatment. The importance of a close coopera-tion between paediatric...

  16. Traethedsbrud af collum femoris hos rask maratonløber

    DEFF Research Database (Denmark)

    Nielsen, Klaus; Christensen, Ole; Lukina, Guy Feruzi

    2009-01-01

    Fatigue fractures of the hip are rare causes of hip pain. Delayed diagnostics of this type of fracture can cause serious complications. We describe a case concerning a 32-year-old male amateur runner who experienced hip pain with rapid onset during his first marathon. After eight days his general......-old male amateur runner who experienced hip pain with rapid onset during his first marathon. After eight days his general practitioner referred him to the hospital and a dislocated fracture of the femoral neck was detected. Udgivelsesdato: 2009-Oct-5 Udgivelsesdato: 2009...

  17. Antithyroideaantistof hos to patienter med subakut dementiel udvikling, ataksi og myoklonus

    DEFF Research Database (Denmark)

    Kondziella, Daniel; Hansen, Klaus; Gonzalez, Teresa

    2012-01-01

    Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus and posit......Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus...... and positive antithyroid antibodies were given oral steroids. Whereas one progressively declined and had histopathologically proven CJD, the other made a complete recovery and was diagnosed with HE. Anti-thyroid antibodies can occur in CJD, but when present in a patient with subacute dementia, ataxia...

  18. Leversygdom hos børn kan forekomme uden forhøjelse af leverspecifikke enzymer

    DEFF Research Database (Denmark)

    Caverius, Anna Ulrika; Jørgensen, Marianne Hørby; Lausen, Birgitte;

    2015-01-01

    In children, liver diseases are rarely suspected without elevated levels of liver transaminases. We describe two cases of portal hypertension of children who presented with gastrointestinal bleeding, splenomegaly and cytopenia. Both cases had normal levels of liver transaminases; thus...... haematological conditions initially were suspected. An elevated alanine aminotransferase level should always lead to further examination to detect liver diseases in early stages, in order to limit development of cirrhosis....

  19. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Ali Qayyum, Abbas; Kastrup, Jens

    2015-01-01

    ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.......The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic...

  20. Kroniske lungeforandringer hos børn med langvarig produktiv hoste

    DEFF Research Database (Denmark)

    Foghsgaard, Jakob; Nir, Marta; Marthin, June K;

    2009-01-01

    A productive (sounding) cough is always abnormal, and suppurative lung disease should be considered. A chronic suppurative cough may be associated with the destruction of the bronchial wall (bronchiectasis). The most commonly identifiable cause of suppurative cough is cystic fibrosis. This article......, which is accompamied by an illustrative CT-scan, describes two paediatric cases of cystic fibrosis and primary ciliary dyskinesia and suggests appropriate avenues of clinical investigation, when chronic suppurative cough presents in children. Udgivelsesdato: 2009-Jan-26...

  1. Anaboliske-androgene steroiders effekt på muskelstyrke, kropsvaegt og fedtfri legemsmasse hos styrketraenende maend

    DEFF Research Database (Denmark)

    Søe, Martin Jensen; Jensen, K L; Gluud, C

    1989-01-01

    A review of the effects of anabolic-androgenic steroids (AAS) on muscle strength, body weight and lean body mass in body-building men is presented. In about half of the placebo-controlled studies, a significant effect on the above mentioned response variables is found. In all cases where an effect...

  2. Forebyggelse og behandling af fedme hos børn og unge

    DEFF Research Database (Denmark)

    Michaelsen, Kim Fleischer; Mølgaard, Christian; Richelsen, Bjørn

    2006-01-01

    In the last 10 years, there has been a marked increase in the prevalence of obesity in children beginning at 3-4 years of age. The only realistic solution to the problem is prevention. Although there is limited evidence for the effectiveness of preventive programmes, there is a consensus...... that multisectorial action is urgently needed. This should include intervention at the family, school, municipal, regional and national levels, including the commercial sector and food companies. Treating childhood obesity has not been very successful, but some comprehensive community-based treatment programmes have...

  3. Den HPV-relaterede sygdomsbyrde hos mænd er stor og kan forebygges

    DEFF Research Database (Denmark)

    Kiellberg Larsen, Helle; Kofoed, Kristian; Sand, Carsten

    2013-01-01

    Human papillomavirus (HPV) is a highly prevalent sexually transmitted infection. High-risk HPV causes penile cancer and a substantial proportion of oropharyngeal and anal malignancy in men. Low-risk types of HPV cause anogenital warts. The incidence of oropharyngeal and anal cancers is increasing...... in Denmark. Prevention of penile, anal and oropharyngeal cancers and anogenital warts represents potential benefits of the HPV vaccine; and vaccination of men is now recommended by the Australian and the North American health authorities. Thus, we recommend that the Danish HPV vaccination program should...

  4. Et Patientperspektivistisk Studie i Brug af Alternativ Behandling hos Danske Patienter med Diabetes

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2008-01-01

    clients, however, are positioned as user of both complementary and alternative medicine and conventional treatments, such as biological, homeopathic, and traditional Chinese medicine. The main factors that drive them to this are the aim, the hope, the belief, and knowledge how to cure diabetes. Conclusion......: The study shows that the decisive difference of how diabetics are positioned as to complementary and alternative self-care is the way in which they have the strength and hope, believe and knowledge of how to cure disease which by people in general is regarded as chronic.......Background and objectives: There have not earlier been studies focusing on experiences of Danish diabetic patients using Complementary and Alternative Medicine (CAM) – considered from the patients’ point of view. The existing studies mostly based on quantitative methods of patients with diabetes...

  5. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Qayyum, Abbas Ali; Kastrup, Jens

    2015-01-01

    The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic isch...

  6. Et godt sted at græde og le hos Helle Helle

    DEFF Research Database (Denmark)

    Hansen, Per Krogh

    2014-01-01

    Da Helle Helle (f. 1965) i 2010 blev indstillet af Statens Kunstfonds repræsentantskab til at modtage livsvarig kunstnerydelse, lød begrundelsen, at hun var ”en af Danmarks vigtigste fortolkere af middelklassen og den danske provins.” Og sådan er hun generelt også blevet modtaget og fortolket: Som...

  7. Seksuel transmission af hepatitis C-virus hos hiv-inficerede maend

    DEFF Research Database (Denmark)

    Peters, Lars; Weis, Nina M; Lindhardt, Bjarne Orskov

    2006-01-01

    Infections with the hepatitis C virus (HCV) occur primarily through percutaneous transmission, while sexual transmission seems to be rare. Recently, in some European cities, an increasing incidence of sexually transmitted HCV infection among HIV-infected homosexual males has been reported. We...... describe four cases of acute HCV infection among HIV-infected homosexual males, where sexual transmission was likely. Udgivelsesdato: 2006-Oct-16...

  8. beta-thalassaemia major hos børn og unge i Danmark

    DEFF Research Database (Denmark)

    Jung, Anne; Main, Katharina Maria; Scheibel, Elma

    2002-01-01

    INTRODUCTION: Beta-thalassemia major occurs with increasing frequency among Danish children as a result of immigration. The aim of the study was to estimate the occurrence of beta-thalassemia major in Denmark, analyse the treatment and organ functions, and identify areas for an improved treatment...... strategy. MATERIAL AND METHODS: During 1998-99 all Danish pediatric departments were contacted for identification of children aged 0-18 years with beta-thalassemia major. Blood transfusions and chelation therapy were registered, and for Eastern Denmark clinical, endocrine, cardiac, and serologic parameters...... were performed. RESULTS: Twenty-six children had beta-thalassemia major. Out of these, 20 received blood transfusions, and 17 patients were chelated. Eight patients were not chelated owing to previous bone marrow transplantation, treatment with hydroxyurea or ferritin

  9. Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

    DEFF Research Database (Denmark)

    Poulsen, Christina Gjerlev; Bestle, Morten; Boesby, Lene

    2017-01-01

    In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration...

  10. Prognostisk vaerdi af PET og MRS ved evaluering af cerebral status hos børn

    DEFF Research Database (Denmark)

    Borgwardt, Lise; Danielsen, Else Rubaek; Børch, Klaus

    2002-01-01

    We report a case of a 12-week-old previously normal infant with severe brain damage after an episode of asphyxia during an RS-virus infection. Sub-acute MRI was normal, but new functional techniques, PET (positron emission tomography) and MRS (magnetic resonance spectroscopy) were severely abnorm....... At an outpatient clinic three months later, he had developed microencephaly and the MRI was now severely abnormal. The case shows the importance of using multimodality functional imaging techniques to assess the cerebral status of infants for prognosis and course of treatment....

  11. Kan falltendens og brudd hos eldre forebygges med D-vitamin?

    OpenAIRE

    Braaten, Monica Marie

    2011-01-01

    Falls and fractures are common in older people, and are closely related as most fracture are due to falls. Vitamin D deficiency causes osteopenia, osteoporosis and osteomalacia, and in the last decade, implications of insufficiency have interested many researchers. Research has shown conflicting results regarding the effect of vitamin D. Intake of only vitamin D has shown small or no effect , whereas in combination with calcium it has been reported significant reduction of falls and fracture...

  12. Diabetisk ketoacidose hos en hiv-positiv patient i antiretroviral behandling

    DEFF Research Database (Denmark)

    Holm, Malene Rahbek; Hansen, Birgitte Rønde; Røder, Michael E

    2006-01-01

    inhibitors (PI), in particular, has been associated with insulin resistance and hyperglycaemia, but only infrequently with diabetic ketoacidosis. We report a case of diabetic ketoacidosis in an HIV-infected woman after 1(1/2) years of a PI-containing regimen, demonstrating reduced beta cell function...... and insulin resistance. Udgivelsesdato: 2006-Feb-27...

  13. Cancer prostatae hos maend under 65 år. Forekomst og behov for udredning

    DEFF Research Database (Denmark)

    Brasso, K; Friis, S; Kjaer, S K;

    1997-01-01

    Based on information from the nationwide Danish Cancer Registry, the development in prostate cancer incidence among Danish men under 65 years is reviewed. Changes in incidence rate, clinical stage and the number of possible candidates for radical treatment are discussed....

  14. Intratekal baclofenbehandling ved svaer spastisk tetraplegi og dystoni hos børn og unge

    DEFF Research Database (Denmark)

    Illum, Niels Ove; Hansen, Flemming Juul; Fischer, Claudia

    2003-01-01

    INTRODUCTION: Continuous intrathecal baclofen has been used over the past years especially in adult patients with spasticity of spinal origin. Children and young adults with severe spasticity and dystonia of cerebral origin are difficult to treat in spite of optimal systemic antispasmotic therapy...

  15. Spørgeskemaer om adfærd hos førskolebørn

    DEFF Research Database (Denmark)

    Kristensen, Solvejg; Bilenberg, Niels

    2009-01-01

    This article presents an American psychometric instrument; the Child Behavior Checklist for Ages 1-5 (CBCL/1-5) appropriate for application in the clinical setting and in research for assessment of behavioural, emotional and social problems in preschool children. Selected scores from a Danish...... population-based sample and a clinical sample on the CBCL/1-5 and the Caregiver Report Form (C-TRF) are presented. CBCL/1-5 and C-TRF seem reliable and valid for assessing psychopathological problems in preschool children from the perspectives of multiple informants in diverse settings. Udgivelsesdato: 2009...

  16. Metoder til måling af ketose hos søer

    DEFF Research Database (Denmark)

    Olesen, Anja Kibsgaard; Theil, Peter Kappel; Kristensen, Niels Bastian

    2010-01-01

    kunne være en laboratoriebaseret, enzymatisk målemetode på plasma eller serum. Denne metode kræver dog, at der udtages blodprøver af søerne, samt at disse prøver sendes til et laboratorium og centrifugeres. Denne form for analyse er dermed meget ressourcekrævende, og resultaterne fås ikke samme dag. Der...

  17. Recirkulering af fosfor hos malkekøer

    DEFF Research Database (Denmark)

    2010-01-01

    den samme recirkulering af fosfor på trods af et lavere P indtag. Konsekvensen var dog, at P balancen faldt, og indikerer at recirkulering af P til vommen blev opretholdt på bekostning af køernes mulighed for deponering på knoglerne. Alligevel var køerne ikke i stand til at opretholde plasma- og...

  18. Demyeliniserende sygdom hos børn med akutte neurologiske symptomer

    DEFF Research Database (Denmark)

    Olofsson, Isa Amalie; Skov, Liselotte; Miranda, Maria Jose

    2016-01-01

    Demyelinating diseases in children is a broad group of illnesses, which affect the central nervous system. Demyelinating diseases can be monophasic or chronic and comprise acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, multiple sclerosis and neuromyelitis optica...

  19. Demyeliniserende sygdom hos børn med akutte neurologiske symptomer

    DEFF Research Database (Denmark)

    Olofsson, Isa Amalie; Skov, Liselotte; Miranda, Maria Jose

    2015-01-01

    Demyelinating diseases in children is a broad group of illnesses, which affect the central nervous system. Demyelinating diseases can be monophasic or chronic and comprise acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, multiple sclerosis and neuromyelitis optica...

  20. Lesbisk selvtillit – lesbisk helse. Utfordringer og mestringsstrategier hos lesbiske kvinner

    OpenAIRE

    Bjørkman, Mari

    2012-01-01

    Lesbian women make up a sexual minority within a heteronormative society where homosexuality becomes invisible and inferior. Minority stress is the excess stress individuals from stigmatized social categories experience because of their minority position. Stress may influence health and identity. It is not the burden of stress itself that determines its influence on health and identity, but how the individual copes with the stress. Existing research indicates that having a lesb...

  1. Peritoneal tuberkulose hos en tidligere rask 20-årig dansk kvinde

    DEFF Research Database (Denmark)

    Hansen, Kristina Bjerre; Wejse, Christian

    2014-01-01

    Peritoneal tuberculosis (PT) is very uncommon and presents a diagnostic challenge, especially in women. Patients often present with non-specific symptoms mimicking advanced stage ovarian cancer. In this case a 20-year-old woman without known exposure to tuberculosis presented with abdominal...

  2. Gode resultater efter Hartmanns operation for cancer recti hos højrisikopatienter

    DEFF Research Database (Denmark)

    Togsverd-Bo, Morten; Gögenur, Ismail; Harvald, Thomas;

    2010-01-01

    The purpose of this study was to evaluate the incidence of per- and postoperative complications of low anterior resection and Hartmann's operation (HO) for rectal cancer. The study was performed in a department with a high frequency of HO....

  3. Svær overvægt hos børn og unge

    DEFF Research Database (Denmark)

    Kloppenborg, Julie Tonsgaard; Holm, Jens-Christian

    2016-01-01

    disease regulated by a complex neuroendocrine system aiming at fat mass preservation. Multidisciplinary chronic care treatment based on current guidelines, meta-analyses, systematic reviews, and best-practice standards across health sectors are recommended to alleviate and counteract childhood obesity.......The ongoing childhood obesity pandemic is a comprehensive health challenge in the 21st century with major implications for mental and physical health and disease with an increased morbidity and mortality resulting in a shortening of expected life span. Obesity should be understood as a chronic...

  4. Fallhendelser hos eldre i hjemmetjenesten i en norsk kommune- omfang og omstendigheter

    Directory of Open Access Journals (Sweden)

    Rita Solbakken

    2015-06-01

    Full Text Available Fall events in elder recipients of home care services in a Norwegian municipality- incidence and circumstancesFalls in institutional care are adverse events that have been well documented. Falls among elderly in home care services have not previously been studied in Norway. The aim of this study was to register the incidence and circumstances surrounding falls occurring in home-care services for elderly persons in a medium-sized Norwegian municipality. Descriptive statistics was applied in a three-month follow up study. Totally 440 homebound elderly aged 65 years or more and receiving home care services or safety alarm were included in this study. In total 101 falls, represented by 72 persons were documented. Sixty six percent reported no injury related to the fall, but 34% had injuries, ranging from bruises to fractures and hospitalization. In 24 % the circumstances were unknown, for the rest there was no particular cause documented. The findings will be used to study the development of care and prevention of falls with elder persons in home care services.

  5. Fatal hæmofagocytisk lymfohistiocytose og mononukleose hos en patient med colitis ulcerosa

    DEFF Research Database (Denmark)

    Juul Ingvardsen, Charlotte; Ballegaard, Vibe Cecilie; Homøe, Preben

    2012-01-01

    We report a case of Epstein-Barr virus primo infection with the development of lethal haemophagocytic lymphohistiocytosis (HLH) in a 22 year-old man, who was being treated with azathioprin for colitis ulcerosa. HLH is a rare, life-threatening disease, which is caused by an inappropriate activation...

  6. Diagnostisk strategi hos patienter, der er henvist til skadestuen pa mistanke om dyb venos trombose

    DEFF Research Database (Denmark)

    Mantoni, M.Y.; Kristensen, M.; Brogaard, M.H.;

    2008-01-01

    patients with normal D-dimer had high DVT-scores, none had DVT, so that the benefit from determining DVT-scores was modest. Ultrasound scanning revealed DVT in 85 out of 397 patients with elevated D-dimer. A repeat examination was performed in 91 patients with persisting symptoms, and disclosed DVT in two......INTRODUCTION: The standard method for diagnosing deep vein thrombosis (DVT) involves determination of D-dimer and ultrasound scanning. In an attempt to reduce the number of ultrasound examinations we have supplemented this with a clinical probability estimate for DVT (DVT-score) over one year...... fossa. If no DVT was revealed, the patient was contacted by telephone 7-10 days later, and was offered a repeat examination if symptoms persisted. RESULTS: Three patients with chronic DVT were excluded. Normal D-dimer and low or moderate DVT-score was found in 103 patients, none had DVT. Only five...

  7. Fruktbarhet hos simler: effekter av ernæring og vekst

    Directory of Open Access Journals (Sweden)

    N.J.C. Tyler

    1988-06-01

    Full Text Available Tyler's article is published in English in Rangifer 7 (2, 1987: Fertility in female reindeer: the effect of nutrition and growth.Sammendrag: Drektighetsprosenten i ungrein varierer sterkt fra individ til individ og fra flokk til flokk. En høy fruktbarhet i reinflokken er selve grunnlaget for en vellykket reindrift. Overraskende er det derfor at man vet lite om hvilke faktorer som bestemmer om rein skal bli drektig eller ikke. I denne artikkelen blir effekten av ernæring på reinsimlenes fruktbarhet diskutert. Undersøkelser indikerer at rein er som andre pattedyr, der fruktbarheten er relatert til kroppsvekten. Forholdet mellom reinens kroppsvekt og fruktbarhet varierer likevel sterkt. Mye tyder på at drektighetsprosenten i ungrein er avhengig av reintettheten. Dette indikerer at ernæringen er en viktig faktor når det gjelder fruktbarhet i ungrein. Vektspesifikk fruktbarhet kan derfor være en brukbar indikator for reinflokkens fortilgang. I prinsippet vil slike fruktbarhetsundersøkelser gi et tidlig varsel om reintallet er for høyt i forhold til beitegrunnlaget før en markert nedgang i slaktevekten observeres. Etter foredraget til Nic. Tyler hadde Terje Skogland et forberedt innlegg som er gjengitt på norsk. Deretter fulgte en lengre diskusjon som også er gjengitt.

  8. Fruktbarhet hos simler: effekter av ernæring og vekst

    OpenAIRE

    N. J. C. Tyler; Forberedt innlegg v/ Terje Skogland

    1988-01-01

    Tyler's article is published in English in Rangifer 7 (2), 1987: Fertility in female reindeer: the effect of nutrition and growth.Sammendrag: Drektighetsprosenten i ungrein varierer sterkt fra individ til individ og fra flokk til flokk. En høy fruktbarhet i reinflokken er selve grunnlaget for en vellykket reindrift. Overraskende er det derfor at man vet lite om hvilke faktorer som bestemmer om rein skal bli drektig eller ikke. I denne artikkelen blir effekten av ernæring p&a...

  9. Cerebrale senfølger hos tidligt fødte børn

    DEFF Research Database (Denmark)

    Greisen, Gorm

    2011-01-01

    Several instruments implementing spatially resolved near-infrared spectroscopy (NIRS) to monitor tissue oxygenation are now approved for clinical use. The neonatal brain is readily assessible by NIRS and neurodevelopmental impairment is common in children who were in need of intensive care during...... the neonatal period. It is likely that an important part of the burden of this handicap is due to brain injury induced by hypoxia-ischaemia during intensive care. In particular, this is true for infants born extremely preterm. Thus, monitoring of cerebral oxygenation has considerable potential benefit...... methods. Is it a window of opportunity for the establishment of a rational basis before another technology is added to an already overly complex newborn intensive care?...

  10. Kvælstoffiksering hos cyanobakterier og heterotrofe bakterier i kystnære danske farvande

    DEFF Research Database (Denmark)

    Bentzon-Tilia, M.; Traving, S. J.; Mantikci, Mustafa

    organisms. In this overview, I will talk about our work in Danish estuaries with emphasis on N2fixation by heterotrophic diazotrophs. In general, we have measured N2 fixation, examined nitrogenase (nifH) gene composition by next-generation sequencing, and used real-time PCR to quantify distribution of key...... nifH genes or transcripts in situ. We examined diazotrophy over one year in two contrasting, temperate, estuarine systems (Roskilde Fjord and the Great Belt strait; Bentzon-Tilia et al. 2014). In Roskilde Fjord, N2 fixation was mainly accompanied by transcripts related to heterotrophic (e.......g. Pseudomonas sp.) and photoheterotrophic bacteria (e.g. unicellular diazotrophic cyanobacteria group A). In the Great Belt, the first of two N2 fixation peaks coincided with a similar nifH expressing community as in Roskilde Fjord, whereas the second peak was synchronous with increased nifH expression...

  11. Laryngeal neurofibromatose hos et ni måneder gammelt barn

    DEFF Research Database (Denmark)

    Højbak, Anette Fribo Møller; Schollert, Niels Erik; Jensen, Eva Margrethe Precht;

    2011-01-01

    Neurofibroma of the larynx is a very rare condition. A nine month-old boy presented with airway obstruction due to a plexiform neurofibroma of the larynx. It also involved the proximal part of trachea and hypopharynx. Surgical excision was not a possibility. A tracheotomy was performed in order t...

  12. Antibiotikumprofylakse ved tandbehandling hos patienter med hofte- eller knaeledsalloplastik er sjaeldent nødvendig

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Fuursted, Kurt; Holmstrup, Palle;

    2010-01-01

    A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis are ...... are generally more prone to develop periprosthetic infections it can be considered in these cases to give prophylactic antibiotics before more extensive dental treatments.......A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis...

  13. Klima- og miljøvaner hos borgerne i Køge

    DEFF Research Database (Denmark)

    Hoff, Jens Villiam; Nørregaard, Emilie; Ellesgaard, Anders;

    that most people feel that they have all the information needed to change their behavior in a climate-friendly direction, if they want to. Even among the most climate-skeptical citizens, more than half possess a good deal of knowledge on climate challenges. Thus, it takes more than just information...

  14. Tonala skillnader mellan ett tryckande stall och ett limmat stall. : -hos en bouzouki

    OpenAIRE

    Nordwall, Mats

    2006-01-01

    Summary I have a great interest in bouzoukis and since I, during my education in guitar making, mainly have focused on building bouzoukis and other traditional folk instruments, I have chosen the bouzouki as the object of my degree project. In connection to the making of these instruments, I started to consider the construction of the bouzouki and why the bouzouki has such a characteristic sound. One of my theories is based on the fact that most bouzoukis are made with floating bridges instea...

  15. Har beskæftigelsesområdet lavstatus hos socialrådgiverstuderende?

    DEFF Research Database (Denmark)

    Christensen, Anders Bøggild

    2014-01-01

    I mit videncenterprojekt Beskæftigelsespolitik og socialrådgiverprofession har jeg undersøgt socialrådgiverstuderendes opfattelser af beskæftigelsesområdet. Socialrådgivere er oversættere af den statslige politik til borgeren, så nye politiske paradigmer griber dybt ind i professionen. Dette tema...... tematiseres også tit i forskningen og den offentlige debat....

  16. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2015-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences...... between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE. The optimal choice of bone-anti-resorptive agent should depend on the patient...

  17. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2014-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences...... between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE. The optimal choice of bone-anti-resorptive agent should depend on the patient...

  18. Lejringsbetingede skæve hoveder hos spædbørn kan forebygges

    DEFF Research Database (Denmark)

    Knudsen, Birgit; Christensen, Karen; Baagøe, Susanne

    2011-01-01

    The prevalence of positional plagiocephaly is increasing. A systematic database search (Cochrane, MEDLINE, Embase, Cinahl and PEDro), critical appraisal and systematic evaluation of the quality of 14 selected studies show that the following are certain risk factors for the development of position...... plagiocephaly: supine sleeping position, positional preference, one-sided handling of the child, male sex, delayed motor development, reduced neck mobility, too little "tummy time", firstborn, multiple births and premature children. Recommendations for prevention are provided....

  19. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit...... in hospital perforation (adjusted relative risk (RR) 1.87; 95% confidence interval (CI) 0.86-4.05), 2) no classical clinical symptoms of ulcer perforation (adjusted RR with peritonism 0.32; 95% CI 0.14-0.73), 3) first physician attendance later than median time, i.e. > 25 minutes after debut (adjusted RR 2...... size, this audit suggests that long preoperative delay in patients with peptic ulcer perforation is associated with factors related to both the internal organisation of the healthcare system, the patient's pathological picture, and the quality of diagnosis and treatment given. Udgivelsesdato: 2009-Nov...

  20. Rickettsiose er en overset årsag til feber hos den hjemvendte rejsende

    DEFF Research Database (Denmark)

    Kibsgaard, Line

    2012-01-01

    We present two cases of rickettsial infections in travellers caused by Rickettsia typhi and R. africae respectively. The two cases illustrate the widely varying symptomatology and aetiology. Incidence and treatment of the disease are discussed. The diagnosis is complex, and we believe that ricket...... that rickettsiosis is an underestimated cause of fever in returned travellers from the tropics. In the past two years only 26 cases have been diagnosed in Denmark. Whenever rickettsiosis is clinically suspected, empiric treatment with doxycycline should be initiated....

  1. Selvstyring af peroral antikoagulationsbehandling hos børn med medfødte hjertesygdomme

    DEFF Research Database (Denmark)

    Christensen, Thomas Decker; Attermann, Jørn; Hjortdal, Vibeke Elisabeth

    2002-01-01

    that it is also possible in this subset of patients. Our aim was to assess the quality of self-management in children with congenital cardiac disease. MATERIAL AND METHODS: We trained 14 children aged from 2.2 to 15.6 years, with a mean age of 9.7 years, and their parents, in domiciliary analysis...

  2. Langvarig sygdom hos danske børn rapporteret af forældrene

    DEFF Research Database (Denmark)

    Nielsen, Anne M; Koefoed, Birgitte Gade; Møller, Ralf

    2006-01-01

    INTRODUCTION: The aim of this study was to report the prevalence and nature of long-term diseases and their consequences in children under the age of 16 in Denmark, and to identify the socio-demographic determinants of disease. MATERIALS AND METHODS: Parents and stepparents participating...... others from poor health in general, recent sick leave and poor thriving. DISCUSSION: The figures for long-term disease reported by the parents participating in the study were in accordance with what was found in earlier studies, but stigmatising and less severe diseases, as well as periodically recurring...

  3. Beta-thalassaemia major hos børn og unge i Danmark

    DEFF Research Database (Denmark)

    Jung, A.; Main, K.M.; Scheibel, E.

    2002-01-01

    INTRODUCTION: Beta-thalassemia major occurs with increasing frequency among Danish children as a result of immigration. The aim of the study was to estimate the occurrence of beta-thalassemia major in Denmark, analyse the treatment and organ functions, and identify areas for an improved treatment...... strategy. MATERIAL AND METHODS: During 1998-99 all Danish pediatric departments were contacted for identification of children aged 0-18 years with beta-thalassemia major. Blood transfusions and chelation therapy were registered, and for Eastern Denmark clinical, endocrine, cardiac, and serologic parameters...

  4. Primært gastrointestinale symptomer ved malaria hos flygtningebørn

    DEFF Research Database (Denmark)

    St-Martin, Gry; Thusgaard, Mikkel; Simonsen, Hanne Marie

    2009-01-01

    We present three cases of malaria in refugee children newly arrived from Sub-saharan Africa. Only one of the three children had fever and all had high parasite loads (2,5-14% parasitemia). Malaria is an important differential diagnosis in refugees from endemic areas, regardless of whether...

  5. Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Blinkenberg, M; Rune, K; Jensen, C V;

    2001-01-01

    Magnetic resonance imaging (MRI) lesion load is widely used in the clinical evaluation of patients with multiple sclerosis (MS), but little is known about the associated changes in cortical activation. For this purpose, we studied the association between the corticocerebral metabolic rate...

  6. Subjektive hukommelsesklager hos aeldre. Er det tegn på demens?

    DEFF Research Database (Denmark)

    Vogel, Asmus

    2008-01-01

    Subjective memory complaints are common in older people. They are inconsistently related to current cognitive impairment, but are more consistently correlated to future development of dementia. Subjective memory complaints are also related to depression and personality traits. Many patients...... with dementia have impaired awareness of deficits even in the early stages of dementia and therefore do not complain about memory problems. Reports about impaired memory in older people should lead to diagnostic examination....

  7. Rinitis og astma hos en rengøringsassistent i et dyreeksperimentelt laboratorium

    DEFF Research Database (Denmark)

    Svendsen, Susanne Wulff; Omland, Øyvind

    2008-01-01

    After 15 years as a cleaner of laboratory animal facilities, a 59-year-old woman developed rhinitis and then mild asthma. One of her main job tasks was manual cleaning of cages. Her symptoms appeared shortly after an automatic cage washer was introduced where she placed dirty cages upside down...

  8. Nyopstået dyspnø med fatal udgang hos en ung, rask kvinde

    DEFF Research Database (Denmark)

    Lidegaard, Øjvind; Hansen, Nikolaj Friis

    2007-01-01

    A 20-year old previously healthy woman who had been taking oral contraceptives for 2 years develops increasing dyspnoea, general ill-feeling and lower back pain over a matter of weeks. During this time she attends her general practitioner several times. She is primarily treated for what...... was in vain. Medicolegal obduction demonstrates severe double pulmonary embolism (saddle embolism). When a young previously healthy woman develops dyspnoea, the possibility of pulmonary embolism should be in mind because timely diagnosis and treatment is crucial for the prognosis. Oral contraceptives should...

  9. Selective mobilization of critical elements in incineration ashes; Selektiv mobilisering av kritiska element hos energiaskor

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Malin; Herrmann, Inga; Ecke, Holger [Luleaa Univ. of Technology (Sweden); Sjoeblom, Rolf [TEKEDO AB, Nykoeping (Sweden)

    2005-05-01

    In the project SMAK, the selective mobilization of critical elements in ashes was studied. Non-hazardous bottom ash from Daava kraftvaermeverk, Umeaa, and hazardous fly ash from Hoegdalenverket, Stockholm, line P6 were investigated. Sb, Mo, Cu, Cr and Cl{sup -} were identified as critical elements in the bottom ash since these elements exceeded the limit values for acceptance on landfills as inert waste according to the Council decision on acceptance criteria at landfills. Critical elements in the fly ash were Cr, Se, Pb and Cl{sup -}, these elements exceeded the limit values for acceptance on landfills as non-hazardous waste. The mobilization of the critical elements was studied in experiments performed according to a reduced 2{sup 6-1} factorial design with three centerpoints. Factors in the experiments were ultrasonic pre-treatment, pre-treatment with carbonation, L/S-ratio, pH, time and temperature. Empirical models of the mobilization were used to identify the optimal factor setting ensuring sufficient mobilization of critical elements, i.e. to achieve a solid residue meeting non-hazardous and inert landfill criteria for fly ash and bottom ash, respectively. No ultrasonic treatment, pre-treatment with carbonation, L/Sratio 5, pH 12, time 2h and temperature at 20 deg C were identified as optimal factor setting for the bottom ash. For the fly ash, no ultrasonic treatment, no pre-treatment with carbonation, L/S-ratio 5, pH 7, time 2h and temperature at 20 deg C were identified as optimal factor setting. The treatment with optimal factor settings did not change the classification according to the Council decision on acceptance criteria at landfills of neither ash. For the bottom ash, Sb, Mo and Cr exceeded the limit values for landfilling as inert waste according to the Council decision on acceptance criteria at landfills. Only Cr exceeded the limit value for landfilling the fly ash as non-hazardous waste. According to the Waste Decree (Avfallsfoerordningen) both treated ashes were classified as non-hazardous waste. No negative effects on the geotechnical usage could be found in the classification according to the Waste Decree. A comparison to the general guidance values for contaminated soil according to the Swedish Environmental Protection Agency showed that both of the treated ashes did not meet the limit value for less sensitive land use. Since the ash properties deviated from the reference soil in the general guidance values for contaminated soil according to the Swedish Environmental Protection Agency, a case in point was calculated. The results showed that both ashes met the recommended limit values for less sensitive land use, with and without groundwater usage for households. The main reason for this is that substances which may influence health and environment are maintained much more strongly in the ash as compared to the soil that The Swedish Environmental Protection Agency used in its calculations for the reference values for contaminated soil. This implies that the content of such substances in the groundwater will be low and thereby also any possible effects arising in the different scenarios. (In certain cases it is possible that the ash will behave as a sink for hazardous substances even in cases where the content in the ash will exceed that of the surrounding soil.)

  10. Ballonbehandling og koronar bypasskirurgi hos aeldre. Forekomst, komplikationer og mortalitet 1999-2003

    DEFF Research Database (Denmark)

    Tjerrild, Stinne Bennike; Jakobsen, Anne Mette Prammann; Poulsen, Tina Svenstrup;

    2006-01-01

    INTRODUCTION: Persons over 70 years of age are the fastest-growing segment of the population. A major proportion of these elderly have ischemic heart disease and may need treatment. We describe the development of mechanical coronary revascularization in patients aged 70-79 years versus those 80...... years of age or older over a five-year period. MATERIALS AND METHODS: During 1999, 2001 and 2003, a total of 774 patients over 70 years of age had coronary angioplasty (PCI) or coronary artery bypass surgery (CABG) performed at Odense University Hospital. The patients were separated according to type...... number of coronary revascularizations in the elderly increased. The main reason for this was a marked increment in the use of PCIs and a general increase in the use of revascularizations in patients 80 years of age or older. PCI in the elderly is associated with a lower frequency of complications...

  11. Anaemi - praevalens og ætiologi hos patienter indlagt på en geriatrisk afdeling

    DEFF Research Database (Denmark)

    Pedersen, Andreas James Thestrup; Skjelbo, Erik

    2008-01-01

    interval 51-71%) than among women (27%, 95% confidence interval 21-34%). 30 of the anemic patients (27%) had anemia listed as a diagnosis, including 14 with the diagnosis anemia without specification. A minority of anemic patients had measurements of serum ferritin (37%), serum iron (10%), plasma cobalamin...... with that suggested in the literature. MATERIALS AND METHODS: Age, sex and hemoglobin concentrations (hgb) were registered for patients referred to the acute geriatric ward of Odense University Hospital between 6/1/04 and 8/31/04. The prevalence of anemia was determined on the basis of the local laboratory's sex...

  12. Visceral leishmaniasis hos to børn efter ferie i Sydeuropa

    DEFF Research Database (Denmark)

    Castberg, Filip Christian; Poulsen, Anja; Petersen, Bodil Laub

    2013-01-01

    Pancytopenia, fever and splenomegaly are frequent causes for referrals to paediatric haematology departments, on the suspicion of acute leukaemia. We report two cases of Danish children with the tropical disease visceral leishmaniasis (VL) contracted on short vacations in Southern Europe. One...

  13. Tre tilfaelde af visceral leishmaniasis: det ene hos en HIV-positiv mand

    DEFF Research Database (Denmark)

    Balslev, U; Jonsbo, F; Junge, Jette

    1991-01-01

    Three cases of visceral leishmaniasis (kala-azar) are presented. One of these was in a 43-year-old patient with AIDS who was infected in Southern Spain. Another was in a man aged 25 years infected in West Africa. These cases are the first two adults to be reported in Denmark. The third case...

  14. Hyppighed af astma hos skolebørn. Er sygdommen underdiagnosticeret?

    DEFF Research Database (Denmark)

    Høst, A H; Duus, T; Ibsen, T B

    1993-01-01

    with measurement of peak expiratory flow rate (PEFR) before and after six minutes running. Seventy-five (8.8%) had had previous periods of recurrent wheezing, and 535 (62.7%) were exposed to tobacco smoking at home. A correlation was found between passive smoking and previous recurrent wheezing. Thirty-four (4.0...... on significant exercise-induced fall in PEFR and/or a significantly increased variability of PEFR of at least 15% as measured by home recordings of PEFR. In conclusion the point prevalence of asthma diagnosed by a physician was 4.0%. In addition at least 3.2% had reproducible significant bronchial...

  15. Æstetiske forudsætninger for Oplysningen hos Kant

    Directory of Open Access Journals (Sweden)

    Kasper Hertz Jansen

    2015-03-01

    Full Text Available Immanuel Kant's ‘Critique of Judgment’ is often read either in terms of art appreciation or teleology. In this paper however, the object is to examine the ‘Critique of Judgment’, especially the concepts of the Beautiful and the Sublime, in relation to the Kantian version of the Enlightenment. The main theses in the paper are as following: That Beauty can provide us with the sensuous experience of the possibility of the moral law and that the Sublime can provide us with the sensuous experience of the possibility that we as rational beings can effectuate the actual existence of the moral law.

  16. Halms effekt på mavesår hos slagtesvin

    DEFF Research Database (Denmark)

    Jørgensen, Lisbeth; Pedersen, Lene Juul; Herskin, Mette S.

    2015-01-01

    Tildeling af halm i stien til slagtesvin svarende til op til ca. 300 g pr. gris pr. dag fjernede ikke, men reducerede forekomsten af mavesår/-ar og gav et fastere maveindhold.......Tildeling af halm i stien til slagtesvin svarende til op til ca. 300 g pr. gris pr. dag fjernede ikke, men reducerede forekomsten af mavesår/-ar og gav et fastere maveindhold....

  17. Smerter i nakken hos børn kan skyldes retrofaryngeal absces

    DEFF Research Database (Denmark)

    Schoos, Ann-Marie Malby; Damgaard, Bodil; Jeppesen, Eva Mosfeldt

    2012-01-01

    A six-year-old boy presented with fever, neck pain, and ear pain. Within days, the motility of his neck limited, his temperature rose, and blood samples showed signs of infection. On suspicion of cervical spondylodiscitis, a bone scintigraphy was performed, but gave negative results. A magnetic r...... resonance imaging of the neck area showed results, which led to the diagnosis of a retropharyngeal abscess. This case is a reminder that retropharyngeal abscess poses a diagnostic challenge for the physician, and that the prognosis is potentially serious....

  18. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    of concentration, and inability to remember. Short-term memory was objectively assessed. We did not find any significant changes in either peripheral blood pressures, walking distances or the severity of leg pain. Systemic blood pressure was reduced both by placebo and GB-8. The impairment of concentration...... and the inability to remember were both reduced, when comparing results during active treatment to placebo. Short-term memory did not change significantly. In conclusion, our study has shown that treatment with the Ginkgo biloba extract GB-8 improves some cognitive functions in elderly patients with moderate...

  19. Kombination af aliskiren og losartan hos patienter med type 2-diabetes og nefropati - Sekundaerpublikation

    DEFF Research Database (Denmark)

    Parving, Hans-Henrik; Persson, Frederik; Lewis, Julia B

    2009-01-01

    We evaluated the renoprotective effects of adding aliskiren to treatment with losartan in hypertensive patients with type 2 diabetes and nephropathy. A total of 599 patients were randomized to six months of treatment with placebo or aliskiren in addition to losartan 100 mg and optimal...

  20. Implementering av nye GOLD-stadier hos pasienter med KOLS i allmennpraksis

    OpenAIRE

    Storaker, Marit Aarvaag; Nerwey, Ibrahim; Kierulf-Strømme, Kirsten; Tengesdal, Randi Hauge; Wyller, Nora Guttormsgaard; Skårn, Elling Skeide; Cagrici, Ufuk

    2014-01-01

    Bakgrunn: GOLD (Global Initiative for Chronic Obstructive Lung Disease) lanserte i 2011 nye kriterier for gradering av alvorlighetsgrad av KOLS, der man i tillegg til FEV1 ved spirometri også tar hensyn til antall eksaserbasjoner og pasientens symptombyrde. Mange pasienter havner i en lavere risikogruppe etter den nye inndelingen, og er følgelig overbehandlet med f.eks. inhalasjonssteroider. Andre kan identifiseres tidligere som høyrisikopasienter for hyppige eksaserbasjoner og raskt tap av l...