WorldWideScience

Sample records for atms software project

  1. Automated transportation management system (ATMS) software project management plan (SPMP)

    Energy Technology Data Exchange (ETDEWEB)

    Weidert, R.S., Westinghouse Hanford

    1996-05-20

    The Automated Transportation Management System (ATMS) Software Project Management plan (SPMP) is the lead planning document governing the life cycle of the ATMS and its integration into the Transportation Information Network (TIN). This SPMP defines the project tasks, deliverables, and high level schedules involved in developing the client/server ATMS software.

  2. Automated Transportation Management System (ATMS) Software Project Management Plan (SPMP). Revision 2

    International Nuclear Information System (INIS)

    Weidert, R.S.

    1995-01-01

    As a cabinet level federal agency with a diverse range of missions and an infrastructure spanning the United States, the US Department of Energy (DOE) has extensive freight transportation requirements. Performance and management of this freight activity is a critical function. DOE's Transportation Management Division (TMD) has an agency-wide responsibility for overseeing transportation activities. Actual transportation operations are handled by government or contractor staff at the field locations. These staff have evolved a diverse range of techniques and procedures for performing transportation functions. In addition to minimizing the economic impact of transportation on programs, facility transportation staff must be concerned with the increasingly complex task of complying with complex shipment safety regulations. Maintaining the department's safety record for shipping hazardous and radioactive materials is a primary goal. Use of automation to aid transportation functions is not widespread within DOE, though TMD has a number of software systems designed to gather and analyze data pertaining to field transportation activities. These systems are not integrated. Historically, most field facilities have accomplished transportation-related tasks manually or with minimal computer assistance. At best, information and decision support systems available to transportation staffs within the facilities are fragmented. In deciding where to allocate resources for automation, facility managers have not tended to give the needs of transportation departments a high priority. This diversity causes TMD significant difficulty in collecting data for use in managing department-wide transportation activities

  3. Automated Transportation Management System (ATMS) Software Project Management Plan (SPMP). Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Weidert, R.S.

    1995-05-26

    As a cabinet level federal agency with a diverse range of missions and an infrastructure spanning the United States, the US Department of Energy (DOE) has extensive freight transportation requirements. Performance and management of this freight activity is a critical function. DOE`s Transportation Management Division (TMD) has an agency-wide responsibility for overseeing transportation activities. Actual transportation operations are handled by government or contractor staff at the field locations. These staff have evolved a diverse range of techniques and procedures for performing transportation functions. In addition to minimizing the economic impact of transportation on programs, facility transportation staff must be concerned with the increasingly complex task of complying with complex shipment safety regulations. Maintaining the department`s safety record for shipping hazardous and radioactive materials is a primary goal. Use of automation to aid transportation functions is not widespread within DOE, though TMD has a number of software systems designed to gather and analyze data pertaining to field transportation activities. These systems are not integrated. Historically, most field facilities have accomplished transportation-related tasks manually or with minimal computer assistance. At best, information and decision support systems available to transportation staffs within the facilities are fragmented. In deciding where to allocate resources for automation, facility managers have not tended to give the needs of transportation departments a high priority. This diversity causes TMD significant difficulty in collecting data for use in managing department-wide transportation activities.

  4. Fy00 Treasure Valley ITS Deployment Project : advanced traffic management system (ATMS) software procurement and implementation process

    Science.gov (United States)

    2006-08-02

    In 2000, the Treasure Valley area of the State of Idaho received a federal earmark of $390,000 to develop an Advanced Transportation Management System (ATMS) for the Treasure Valley region of Idaho. The Ada County Highway District (ACHD), located in ...

  5. ATM

    Directory of Open Access Journals (Sweden)

    Boo Yong Ahn

    1999-01-01

    Full Text Available We model the error control of the partial buffer sharing of ATM by a queueing system M1,M2/G/1/K+1 with threshold and instantaneous Bernoulli feedback. We first derive the system equations and develop a recursive method to compute the loss probabilities at an arbitrary time epoch. We then build an approximation scheme to compute the mean waiting time of each class of cells. An algorithm is developed for finding the optimal threshold and queue capacity for a given quality of service.

  6. Avionics and Software Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the AES Avionics and Software (A&S) project is to develop a reference avionics and software architecture that is based on standards and that can be...

  7. Managing Distributed Software Projects

    DEFF Research Database (Denmark)

    Persson, John Stouby

    Increasingly, software projects are becoming geographically distributed, with limited face-toface interaction between participants. These projects face particular challenges that need careful managerial attention. This PhD study reports on how we can understand and support the management...... of distributed software projects, based on a literature study and a case study. The main emphasis of the literature study was on how to support the management of distributed software projects, but also contributed to an understanding of these projects. The main emphasis of the case study was on how to understand...... the management of distributed software projects, but also contributed to supporting the management of these projects. The literature study integrates what we know about risks and risk-resolution techniques, into a framework for managing risks in distributed contexts. This framework was developed iteratively...

  8. Final report for the protocol extensions for ATM Security Laboratory Directed Research and Development Project

    Energy Technology Data Exchange (ETDEWEB)

    Tarman, T.D.; Pierson, L.G.; Brenkosh, J.P. [and others

    1996-03-01

    This is the summary report for the Protocol Extensions for Asynchronous Transfer Mode project, funded under Sandia`s Laboratory Directed Research and Development program. During this one-year effort, techniques were examined for integrating security enhancements within standard ATM protocols, and mechanisms were developed to validate these techniques and to provide a basic set of ATM security assurances. Based on our experience during this project, recommendations were presented to the ATM Forum (a world-wide consortium of ATM product developers, service providers, and users) to assist with the development of security-related enhancements to their ATM specifications. As a result of this project, Sandia has taken a leading role in the formation of the ATM Forum`s Security Working Group, and has gained valuable alliances and leading-edge experience with emerging ATM security technologies and protocols.

  9. The RETAIN project: DICOM teleradiology over an ATM-based network. Radiological Examinations Transfer on an ATM Integrated Network.

    Science.gov (United States)

    Heautot, J F; Eichelberg, M; Gibaud, B; Tréguier, C; Lemoine, D; Scarabin, J M; Piqueras, J; Carsin, M; Gandon, Y

    2000-01-01

    The RETAIN project (Radiological Examinations Transfer on an ATM Integrated Network) has aimed at testing videoconferencing and DICOM image transfers to get advice about difficult radiological cases over an asynchronous transfer mode (ATM)-based network, which affords a more comfortable interface than narrow-band networks and allows exchange of complete image series using the DICOM format of studies. For this purpose, an experimental ATM network was applied between six university hospitals in four different countries. An assessment of the functionalities of the system was performed by means of log-file analysis, video recording of the sessions and forms filled out by the participants at the end of each session. Questionnaires were answered by the users at the end of the project to bring out perspectives of utilisation and added value. We discussed 43 cases during 20 sessions. For technical or organisational problems, only 20 of the 36 planned sessions took place. The throughput over ATM (10.5 Mbit/s, 20 times faster than six ISDN B-channels) was adequate. Despite the experimental configuration of the network, the system was considered as satisfactory by all the physicians. In 72 % of the sessions, the expected result (answer to the question) was gained. By common consent, videoconferencing was unanimously regarded as a prominent tool in improving the interaction quality. Asynchronous transfer mode is an efficient method for fast transferring of radiologic examinations in DICOM format and for discussing them through high-quality videoconferencing.

  10. Characteristics for Software Optimization Projects

    Directory of Open Access Journals (Sweden)

    Iulian NITESCU

    2008-01-01

    Full Text Available The increasing of the software systems complexity imposes the identification and implementation of some methods and techniques in order to manage it. The software optimization project is a way in which the software complexity is controlled. The software optimization project must face to the organization need to earn profit. The software optimization project is an integrated part of the application cycle because share same resources, depends on other stages and influences next phases. The optimization project has some particularities because it works on an finished product around its quality. The process is quality and performance oriented and it assumes that the product life cycle is almost finished.

  11. Software engineering beyond the project

    DEFF Research Database (Denmark)

    Dittrich, Yvonne

    2014-01-01

    Context The main part of software engineering methods, tools and technologies has developed around projects as the central organisational form of software development. A project organisation depends on clear bounds regarding scope, participants, development effort and lead-time. What happens when...... of traditional software engineering, but makes perfect sense, considering that the frame of reference for product development is not a project but continuous innovation across the respective ecosystem. The article provides a number of concrete points for further research....

  12. Software Project Management

    Science.gov (United States)

    1989-07-01

    incorporated into the sys- Kotler88 tem. Several interesting concepts are presented, but Kotler , P. Marketing Planning: Analysis, Planning, the bulk of the...the development organiza- In some environments, a software product is de- tion. veloped on speculation that there is a market for Teaching Consideration...development houses find it necessary to b. Types of plans know what the potential market for the product There are a number of plans developed in

  13. Gamification in Software Development Projects

    Directory of Open Access Journals (Sweden)

    Platonova Valērija

    2017-12-01

    Full Text Available Gamification is one of the many ways to motivate employees and introduce more fun in daily activities. The aim of the paper is to analyse the impact of gamification method on the software development projects. The paper contains results of a literature review about application areas of gamification, methods, positive and negative effects on projects. The paper also presents an overview of the gamification tools used in software development projects and attempts to answer the question about benefits of gamification usage: whether gamification in the project leads to the desired results and increases the employee productivity and motivation.

  14. Software Quality Assurance in Software Projects: A Study of Pakistan

    OpenAIRE

    Faisal Shafique Butt; Sundus Shaukat; M. Wasif Nisar; Ehsan Ullah Munir; Muhammad Waseem; Kashif Ayyub

    2013-01-01

    Software quality is specific property which tells what kind of standard software should have. In a software project, quality is the key factor of success and decline of software related organization. Many researches have been done regarding software quality. Software related organization follows standards introduced by Capability Maturity Model Integration (CMMI) to achieve good quality software. Quality is divided into three main layers which are Software Quality Assurance (SQA), Software Qu...

  15. Transition to Asynchronous Transfer Mode (ATM) an Implementation Model for NPS Software Metrics Lab

    National Research Council Canada - National Science Library

    Carney, Cameron

    1999-01-01

    With Asynchronous Transfer Mode (ATM), we are experiencing the emergence of a network technology that has the potential of satisfying the requirement for a worldwide standard to allow interoperability of information, regardless...

  16. Management of Software Development Projects

    Directory of Open Access Journals (Sweden)

    Felician ALECU

    2011-04-01

    Full Text Available Any major software development starts with the Initiating process group. Once the charter document is approved, the Planning and then to the Executing stages will follow. Monitoring and Controlling is measuring the potential performance deviation of the project in terms of schedule and costs and performs the related Integrated Change Control activities. At the end, during the Closing, the program/project manager will check the entire work is completed and the objectives are met.

  17. Managing MDO Software Development Projects

    Science.gov (United States)

    Townsend, J. C.; Salas, A. O.

    2002-01-01

    Over the past decade, the NASA Langley Research Center developed a series of 'grand challenge' applications demonstrating the use of parallel and distributed computation and multidisciplinary design optimization. All but the last of these applications were focused on the high-speed civil transport vehicle; the final application focused on reusable launch vehicles. Teams of discipline experts developed these multidisciplinary applications by integrating legacy engineering analysis codes. As teams became larger and the application development became more complex with increasing levels of fidelity and numbers of disciplines, the need for applying software engineering practices became evident. This paper briefly introduces the application projects and then describes the approaches taken in project management and software engineering for each project; lessons learned are highlighted.

  18. ATM Technology Demonstration 1 (ATD-1) Project: Terminal Airspace Technologies for NextGen (Public)

    Science.gov (United States)

    Robinson, John E.; Wang, Easter

    2015-01-01

    This video highlights the human-in-the-loop (HITL) simulations conducted by the ATD-1 project and features visual elements developed for Traffic Management Advisor - Terminal Metering, Controller Managed Spacing, and Flight Deck Interval Management. The video content is fairly technical and intended for audiences that have some knowledge of air traffic management issues. This includes researchers and management from NASA, FAA, industry partners, and others interested in terminal metering, controller managed spacing, and interval management technologies. Please note that the media release only clears the video for peer audiences such as ATM conferences or as part of presentations to researchers.

  19. Estimating software development project size, using probabilistic ...

    African Journals Online (AJOL)

    Estimating software development project size, using probabilistic techniques. ... of managing the size of software development projects by Purchasers (Clients) and Vendors (Development ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  20. Improving Software Engineering on NASA Projects

    Science.gov (United States)

    Crumbley, Tim; Kelly, John C.

    2010-01-01

    Software Engineering Initiative: Reduces risk of software failure -Increases mission safety. More predictable software cost estimates and delivery schedules. Smarter buyer of contracted out software. More defects found and removed earlier. Reduces duplication of efforts between projects. Increases ability to meet the challenges of evolving software technology.

  1. Implementing Large Projects in Software Engineering Courses

    Science.gov (United States)

    Coppit, David

    2006-01-01

    In software engineering education, large projects are widely recognized as a useful way of exposing students to the real-world difficulties of team software development. But large projects are difficult to put into practice. First, educators rarely have additional time to manage software projects. Second, classrooms have inherent limitations that…

  2. Measurement of software project management effectiveness

    OpenAIRE

    Demir, Kadir Alpaslan

    2008-01-01

    Approved for public release; distribution is unlimited. Evaluating, monitoring, and improving the effectiveness of project management can contribute to successful acquisition of software systems. In this dissertation, we introduce a quantitative metric for gauging the effectiveness of managing a software-development project. The metric may be used to evaluate and monitor project management effectiveness in software projects by project managers, technical managers, executive man...

  3. Applied software risk management a guide for software project managers

    CERN Document Server

    Pandian, C Ravindranath

    2006-01-01

    Few software projects are completed on time, on budget, and to their original specifications. Focusing on what practitioners need to know about risk in the pursuit of delivering software projects, Applied Software Risk Management: A Guide for Software Project Managers covers key components of the risk management process and the software development process, as well as best practices for software risk identification, risk planning, and risk analysis. Written in a clear and concise manner, this resource presents concepts and practical insight into managing risk. It first covers risk-driven project management, risk management processes, risk attributes, risk identification, and risk analysis. The book continues by examining responses to risk, the tracking and modeling of risks, intelligence gathering, and integrated risk management. It concludes with details on drafting and implementing procedures. A diary of a risk manager provides insight in implementing risk management processes.Bringing together concepts ...

  4. Software Tools Streamline Project Management

    Science.gov (United States)

    2009-01-01

    Three innovative software inventions from Ames Research Center (NETMARK, Program Management Tool, and Query-Based Document Management) are finding their way into NASA missions as well as industry applications. The first, NETMARK, is a program that enables integrated searching of data stored in a variety of databases and documents, meaning that users no longer have to look in several places for related information. NETMARK allows users to search and query information across all of these sources in one step. This cross-cutting capability in information analysis has exponentially reduced the amount of time needed to mine data from days or weeks to mere seconds. NETMARK has been used widely throughout NASA, enabling this automatic integration of information across many documents and databases. NASA projects that use NETMARK include the internal reporting system and project performance dashboard, Erasmus, NASA s enterprise management tool, which enhances organizational collaboration and information sharing through document routing and review; the Integrated Financial Management Program; International Space Station Knowledge Management; Mishap and Anomaly Information Reporting System; and management of the Mars Exploration Rovers. Approximately $1 billion worth of NASA s projects are currently managed using Program Management Tool (PMT), which is based on NETMARK. PMT is a comprehensive, Web-enabled application tool used to assist program and project managers within NASA enterprises in monitoring, disseminating, and tracking the progress of program and project milestones and other relevant resources. The PMT consists of an integrated knowledge repository built upon advanced enterprise-wide database integration techniques and the latest Web-enabled technologies. The current system is in a pilot operational mode allowing users to automatically manage, track, define, update, and view customizable milestone objectives and goals. The third software invention, Query

  5. Halden project activities on software dependability

    International Nuclear Information System (INIS)

    Dahll, G.; Sivertsen.

    1994-01-01

    Since 1977, the OECD Halden Reactor Project has been working in the field of software dependability. Special emphasis has been put on the use of software in safety critical systems. All phases in software development, from specification through software development, verification, and validation have been covered and are discussed in this article

  6. Antennas Designed for Advanced Communications for Air Traffic Management (AC/ATM) Project

    Science.gov (United States)

    Zakrajsek, Robert J.

    2000-01-01

    The goal of the Advanced Communications for Air Traffic Management (AC/ATM) Project at the NASA Glenn Research Center at Lewis Field is to enable a communications infrastructure that provides the capacity, efficiency, and flexibility necessary to realize a mature free-flight environment. The technical thrust of the AC/ATM Project is targeted at the design, development, integration, test, and demonstration of enabling technologies for global broadband aeronautical communications. Since Ku-band facilities and equipment are readily available, one of the near-term demonstrations involves a link through a Kuband communications satellite. Two conformally mounted antennas will support the initial AC/ATM communications links. Both of these are steered electronically through monolithic microwave integrated circuit (MMIC) amplifiers and phase shifters. This link will be asymmetrical with the downlink to the aircraft (mobile vehicle) at a throughput rate of greater than 1.5 megabits per second (Mbps), whereas the throughput rate of the uplink from the aircraft will be greater than 100 kilobits per second (kbps). The data on the downlink can be narrow-band, wide-band, or a combination of both, depending on the requirements of the experiment. The AC/ATM project is purchasing a phased-array Ku-band transmitting antenna for the uplink from the test vehicle. Many Ku-band receiving antennas have been built, and one will be borrowed for a short time to perform the initial experiments at the NASA Glenn Research Center at Lewis Field. The Ku-band transmitting antenna is a 254-element MMIC phased-array antenna being built by Boeing Phantom Works. Each element can radiate 100 mW. The antenna is approximately 43-cm high by 24-cm wide by 3.3-cm thick. It can be steered beyond 60 from broadside. The beamwidth varies from 6 at broadside to 12 degrees at 60 degrees, which is typical of phased-array antennas. When the antenna is steered to 60 degrees, the beamwidth will illuminate

  7. ATM Technology Demonstration-1 Phase II Boeing Configurable Graphical Display (CGD) Software Design Description

    Science.gov (United States)

    Wilber, George F.

    2017-01-01

    This Software Description Document (SDD) captures the design for developing the Flight Interval Management (FIM) system Configurable Graphics Display (CGD) software. Specifically this SDD describes aspects of the Boeing CGD software and the surrounding context and interfaces. It does not describe the Honeywell components of the CGD system. The SDD provides the system overview, architectural design, and detailed design with all the necessary information to implement the Boeing components of the CGD software and integrate them into the CGD subsystem within the larger FIM system. Overall system and CGD system-level requirements are derived from the CGD SRS (in turn derived from the Boeing System Requirements Design Document (SRDD)). Display and look-and-feel requirements are derived from Human Machine Interface (HMI) design documents and working group recommendations. This Boeing CGD SDD is required to support the upcoming Critical Design Review (CDR).

  8. Security Risk Assessment in Software Development Projects

    OpenAIRE

    Svendsen, Heidi

    2017-01-01

    Software security is increasing in importance, linearly with vulnerabilities caused by software flaws. It is not possible to spend all the project s resources on software security. To spend the resources given to security in an effective way, one should know what is most important to protect. By performing a risk analysis the project know which vulnerabilities they face. A risk analysis will prioritise the vulnerabilities, and when the vulnerabilities are prioritised the project know where th...

  9. Process-based software project management

    CERN Document Server

    Goodman, F Alan

    2006-01-01

    Not connecting software project management (SPM) to actual, real-world development processes can lead to a complete divorcing of SPM to software engineering that can undermine any successful software project. By explaining how a layered process architectural model improves operational efficiency, Process-Based Software Project Management outlines a new method that is more effective than the traditional method when dealing with SPM. With a clear and easy-to-read approach, the book discusses the benefits of an integrated project management-process management connection. The described tight coup

  10. Project Success in Agile Development Software Projects

    Science.gov (United States)

    Farlik, John T.

    2016-01-01

    Project success has multiple definitions in the scholarly literature. Research has shown that some scholars and practitioners define project success as the completion of a project within schedule and within budget. Others consider a successful project as one in which the customer is satisfied with the product. This quantitative study was conducted…

  11. Software project management in a changing world

    CERN Document Server

    Ruhe, Günther

    2014-01-01

    By bringing together various current direc­tions, Software Project Management in a Changing World focuses on how people and organizations can make their processes more change-adaptive. The selected chapters closely correspond to the project management knowledge areas introduced by the Project Management Body of Knowledge, including its extension for managing software projects. The contributions are grouped into four parts, preceded by a general introduction. Part I "Fundamentals" provides in-depth insights into fundamental topics including resource allocation, cost estimation and risk manage

  12. WIPP Transparency Project - container tracking and monitoring demonstration using the Authenticated Tracking and Monitoring System (ATMS)

    International Nuclear Information System (INIS)

    SCHOENEMAN, J. LEE; SMARTT, HEIDI ANNE; HOFER, DENNIS

    2000-01-01

    The Authenticated Tracking and Monitoring System (ATMS) is designed to answer the need for global monitoring of the status and location of proliferation-sensitive items on a worldwide basis, 24 hours a day. ATMS uses wireless sensor packs to monitor the status of the items within the shipment and surrounding environmental conditions. Receiver and processing units collect a variety of sensor event data that is integrated with GPS tracking data. The collected data are transmitted to the International Maritime Satellite (INMARSAT) communication system, which then sends the data to mobile ground stations. Authentication and encryption algorithms secure the data during communication activities. A typical ATMS application would be to track and monitor the stiety and security of a number of items in transit along a scheduled shipping route. The resulting tracking, timing, and status information could then be processed to ensure compliance with various agreements

  13. A review of software project testing

    Directory of Open Access Journals (Sweden)

    Jose Calvo-Manzano Villalón

    2016-03-01

    Full Text Available In this article a review of software projects based on a taxonomy project is established, allowing the development team or testing personnel to identify the tests to which the project must be subjected for validation. The taxonomy is focused on identifying software projects according to their technology. To establish the taxonomy, a development method comprised of 5 phases was applied. The developed taxonomy is comprised of 10 categories and 35 subcategories and was validated by a group of information technology (IT managers and professionals in the field of IT through the use of a survey. The results obtained from the survey are subjected to the Mann-Whitney U test, which indicates that the taxonomy is validated. The taxonomy can be implemented in development organizations with or without a testing team that provides a classification for technology projects.

  14. Testing Software Development Project Productivity Model

    Science.gov (United States)

    Lipkin, Ilya

    Software development is an increasingly influential factor in today's business environment, and a major issue affecting software development is how an organization estimates projects. If the organization underestimates cost, schedule, and quality requirements, the end results will not meet customer needs. On the other hand, if the organization overestimates these criteria, resources that could have been used more profitably will be wasted. There is no accurate model or measure available that can guide an organization in a quest for software development, with existing estimation models often underestimating software development efforts as much as 500 to 600 percent. To address this issue, existing models usually are calibrated using local data with a small sample size, with resulting estimates not offering improved cost analysis. This study presents a conceptual model for accurately estimating software development, based on an extensive literature review and theoretical analysis based on Sociotechnical Systems (STS) theory. The conceptual model serves as a solution to bridge organizational and technological factors and is validated using an empirical dataset provided by the DoD. Practical implications of this study allow for practitioners to concentrate on specific constructs of interest that provide the best value for the least amount of time. This study outlines key contributing constructs that are unique for Software Size E-SLOC, Man-hours Spent, and Quality of the Product, those constructs having the largest contribution to project productivity. This study discusses customer characteristics and provides a framework for a simplified project analysis for source selection evaluation and audit task reviews for the customers and suppliers. Theoretical contributions of this study provide an initial theory-based hypothesized project productivity model that can be used as a generic overall model across several application domains such as IT, Command and Control

  15. Developing Project Duration Models in Software Engineering

    Institute of Scientific and Technical Information of China (English)

    Pierre Bourque; Serge Oligny; Alain Abran; Bertrand Fournier

    2007-01-01

    Based on the empirical analysis of data contained in the International Software Benchmarking Standards Group(ISBSG) repository, this paper presents software engineering project duration models based on project effort. Duration models are built for the entire dataset and for subsets of projects developed for personal computer, mid-range and mainframeplatforms. Duration models are also constructed for projects requiring fewer than 400 person-hours of effort and for projectsre quiring more than 400 person-hours of effort. The usefulness of adding the maximum number of assigned resources as asecond independent variable to explain duration is also analyzed. The opportunity to build duration models directly fromproject functional size in function points is investigated as well.

  16. Wireless ATM : handover issues

    OpenAIRE

    Jiang, Fan; Käkölä, Timo

    1998-01-01

    Basic aspects of cellular systems and the ATM transmission technology are introduced. Wireless ATM is presented as a combination of radio ATM and mobile ATM. Radio ATM is a wireless extension of an ATM connection while mobile ATM contains the necessary extensions to ATM to support mobility. Because the current ATM technology does not support mobility, handover becomes one of the most important research issues for wireless ATM. Wireless ATM handover requirements are thus analysed. A handover s...

  17. ATMS software: Fuzzy Hough Transform in a hybrid algorithm for counting the overlapped etched tracks and orientation recognition

    International Nuclear Information System (INIS)

    Khayat, O.; Ghergherehchi, M.; Afarideh, H.; Durrani, S.A.; Pouyan, Ali A.; Kim, Y.S.

    2013-01-01

    A computer program named ATMS written in MATLAB and running with a friendly interface has been developed for recognition and parametric measurements of etched tracks in images captured from the surface of Solid State Nuclear Track Detectors. The program, using image analysis tools, counts the number of etched tracks and depending on the current working mode classifies them according to their radii (small object removal) or their axis (non-perpendicular or non-circular etched tracks), their mean intensity value and their orientation through the minor and major axes. Images of the detectors' surfaces are input to the code, which generates text and figure files as output, including the number of counted etched tracks with the associated track parameters, histograms and a figure showing edge and center of detected etched tracks. ATMS code is running hierarchically as calibration, testing and measurement modes to demonstrate the reliability, repeatability and adaptability. Fuzzy Hough Transform is used for the estimation of the number of etched tracks and their parameters, providing results even in cases that overlapping and orientation occur. ATMS code is finally converted to a standalone file which makes it able to run out of MATLAB environment. - Highlights: ► Presenting a novel code named ATMS for nuclear track measurements. ► Execution in three modes for generality, adaptability and reliability. ► Using Fuzzy Hough Transform for overlapping detection and orientation recognition. ► Using DFT as a filter for noise removal process in track images. ► Processing the noisy track images and demonstration of the presented code

  18. The advanced software development workstation project

    Science.gov (United States)

    Fridge, Ernest M., III; Pitman, Charles L.

    1991-01-01

    The Advanced Software Development Workstation (ASDW) task is researching and developing the technologies required to support Computer Aided Software Engineering (CASE) with the emphasis on those advanced methods, tools, and processes that will be of benefit to support all NASA programs. Immediate goals are to provide research and prototype tools that will increase productivity, in the near term, in projects such as the Software Support Environment (SSE), the Space Station Control Center (SSCC), and the Flight Analysis and Design System (FADS) which will be used to support the Space Shuttle and Space Station Freedom. Goals also include providing technology for development, evolution, maintenance, and operations. The technologies under research and development in the ASDW project are targeted to provide productivity enhancements during the software life cycle phase of enterprise and information system modeling, requirements generation and analysis, system design and coding, and system use and maintenance. On-line user's guides will assist users in operating the developed information system with knowledge base expert assistance.

  19. Project Management Software for Distributed Industrial Companies

    Science.gov (United States)

    Dobrojević, M.; Medjo, B.; Rakin, M.; Sedmak, A.

    This paper gives an overview of the development of a new software solution for project management, intended mainly to use in industrial environment. The main concern of the proposed solution is application in everyday engineering practice in various, mainly distributed industrial companies. Having this in mind, special care has been devoted to development of appropriate tools for tracking, storing and analysis of the information about the project, and in-time delivering to the right team members or other responsible persons. The proposed solution is Internet-based and uses LAMP/WAMP (Linux or Windows - Apache - MySQL - PHP) platform, because of its stability, versatility, open source technology and simple maintenance. Modular structure of the software makes it easy for customization according to client specific needs, with a very short implementation period. Its main advantages are simple usage, quick implementation, easy system maintenance, short training and only basic computer skills needed for operators.

  20. Bottlenecks in Software Defect Prediction Implementation in Industrial Projects

    OpenAIRE

    Hryszko Jarosław; Madeyski Lech

    2015-01-01

    Case studies focused on software defect prediction in real, industrial software development projects are extremely rare. We report on dedicated R&D project established in cooperation between Wroclaw University of Technology and one of the leading automotive software development companies to research possibilities of introduction of software defect prediction using an open source, extensible software measurement and defect prediction framework called DePress (Defect Prediction in Software Syst...

  1. Requirements: Towards an understanding on why software projects fail

    Science.gov (United States)

    Hussain, Azham; Mkpojiogu, Emmanuel O. C.

    2016-08-01

    Requirement engineering is at the foundation of every successful software project. There are many reasons for software project failures; however, poorly engineered requirements process contributes immensely to the reason why software projects fail. Software project failure is usually costly and risky and could also be life threatening. Projects that undermine requirements engineering suffer or are likely to suffer from failures, challenges and other attending risks. The cost of project failures and overruns when estimated is very huge. Furthermore, software project failures or overruns pose a challenge in today's competitive market environment. It affects the company's image, goodwill, and revenue drive and decreases the perceived satisfaction of customers and clients. In this paper, requirements engineering was discussed. Its role in software projects success was elaborated. The place of software requirements process in relation to software project failure was explored and examined. Also, project success and failure factors were also discussed with emphasis placed on requirements factors as they play a major role in software projects' challenges, successes and failures. The paper relied on secondary data and empirical statistics to explore and examine factors responsible for the successes, challenges and failures of software projects in large, medium and small scaled software companies.

  2. Survey on Projects at DLR Simulation and Software Technology with Focus on Software Engineering and HPC

    OpenAIRE

    Schreiber, Andreas; Basermann, Achim

    2013-01-01

    We introduce the DLR institute “Simulation and Software Technology” (SC) and present current activities regarding software engineering and high performance computing (HPC) in German or international projects. Software engineering at SC focusses on data and knowledge management as well as tools for studies and experiments. We discuss how we apply software configuration management, validation and verification in our projects. Concrete research topics are traceability of (software devel...

  3. Guidance and Control Software Project Data - Volume 1: Planning Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the planning documents from the GCS project. Volume 1 contains five appendices: A. Plan for Software Aspects of Certification for the Guidance and Control Software Project; B. Software Development Standards for the Guidance and Control Software Project; C. Software Verification Plan for the Guidance and Control Software Project; D. Software Configuration Management Plan for the Guidance and Control Software Project; and E. Software Quality Assurance Activities.

  4. Software Engineering Team Project - lessons learned

    Directory of Open Access Journals (Sweden)

    Bogumiła Hnatkowska

    2013-06-01

    Full Text Available In the 2010/11 academic year the Institute of Informatics at Wroclaw University of Technology issued ’Software Engineering Team Project’ as a course being a part of the final exam to earn bachelor’s degree. The main assumption about the course was that it should simulate the real environment (a virtual IT company for its participants. The course was aimed to introduce issues regarding programming in the medium scale, project planning and management. It was a real challenge as the course was offered for more than 140 students. The number of staff members involved in its preparation and performance was more than 15. The paper presents the lessons learned from the first course edition as well as more detailed qualitative and quantitative course assessment.

  5. Software Maintenance Exercises for a Software Engineering Project Course

    Science.gov (United States)

    1989-02-01

    what is program style and how can it be measured? Program style has been defined as a "followed convention with respect to punctuation, capitalization ...convention with respect to punctuation, capitalization , and typographic arrangement and display." *DASC is a software tool that takes a syntactically...Specilleauons: A Frarnewo* * CM-12 Software Metrws CM- 13 Introduction to Softwarell Verification and Validation CM-14 Intelectual Property Protection for

  6. Automated Transportation Management System (ATMS) Configuration Management Plan. Revision 1

    International Nuclear Information System (INIS)

    Weidert, R.S.

    1994-01-01

    This document describes the Software Configuration Management (SCM) approach and procedures to be utilized in developing and maintaining the Automated Transportation Management System (ATMS). The configuration management procedures are necessary to ensure that any changes made to software and related documentation are consistent with ATMS goals and contained securely in a central library. This plan applies to all software and associated documentation used in producing ATMS V1.0 and ATMS V2.0 system

  7. A Framework for Effective Software Monitoring in Project Management

    African Journals Online (AJOL)

    A Framework for Effective Software Monitoring in Project Management. ... is shown to provide meaningful interpretation of collected metric data by embedding certain quality function. Key words: Project Management, Feedback, project control, metrics, process model, quantitative validity ... AJOL African Journals Online.

  8. A Quantitative Study of Global Software Development Teams, Requirements, and Software Projects

    Science.gov (United States)

    Parker, Linda L.

    2016-01-01

    The study explored the relationship between global software development teams, effective software requirements, and stakeholders' perception of successful software development projects within the field of information technology management. It examined the critical relationship between Global Software Development (GSD) teams creating effective…

  9. Software qualification for digital safety system in KNICS project

    International Nuclear Information System (INIS)

    Kwon, Kee-Choon; Lee, Dong-Young; Choi, Jong-Gyun

    2012-01-01

    In order to achieve technical self-reliance in the area of nuclear instrumentation and control, the Korea Nuclear Instrumentation and Control System (KNICS) project had been running for seven years from 2001. The safety-grade Programmable Logic Controller (PLC) and the digital safety system were developed by KNICS project. All the software of the PLC and digital safety system were developed and verified following the software development life cycle Verification and Validation (V and V) procedure. The main activities of the V and V process are preparation of software planning documentations, verification of the Software Requirement Specification (SRS), Software Design Specification (SDS) and codes, and a testing of the software components, the integrated software, and the integrated system. In addition, a software safety analysis and a software configuration management are included in the activities. For the software safety analysis at the SRS and SDS phases, the software Hazard Operability (HAZOP) was performed and then the software fault tree analysis was applied. The software fault tree analysis was applied to a part of software module with some critical defects identified by the software HAZOP in SDS phase. The software configuration management was performed using the in-house tool developed in the KNICS project. (author)

  10. EPRI's POWERCOACH trademark software development project

    International Nuclear Information System (INIS)

    Rost, S.; Leu, Kehshiou

    1993-01-01

    Today's complex bulk power market accounts for an estimated $35 billion in transactions a year, significantly more than a decade ago. With the increased levels of non-utility generation and changing strategies in the utility industry, it is anticipated that the trend toward rapid growth in the bulk power market will continue. This market has evolved from an ad hoc residual market to one that in some respects stands at par with the retail market in the plans of many utilities. The bulk power market is not based on the obligation to serve to the same extent as retail markets. Utility participation in this market is therefore purely voluntary. This freedom of action or inaction in the bulk power market actually renders corporate decision-making, investment related or operational, more complicated in many respects than in retail markets. Examples of the burgeoning uncertainties affecting the bulk power market include the rapid expansion of transactions undertaken through power pools, and the impact on utility planning and operations brought about by the abundance and price attractiveness of power available for flexible periods. These uncertainties present an ideal opportunity to employ state-of-the-art analytical models to facilitate the effective use of utility assets to foster the efficient functioning of the entire bulk power market. This paper will focus on the POWERCOACH methodology for short-term bulk power transaction analysis under conditions of uncertainty. In August 1992, UPMP began a seventeen month project to convert POWERCOACH from a methodology to a fully functional, commercial software package. UPMP is developing the POWERCOACH software with the extensive, direct involvement of thirty EPRI member utilities. A synopsis of POWERCOACH is presented

  11. Predicting Software Projects Cost Estimation Based on Mining Historical Data

    OpenAIRE

    Najadat, Hassan; Alsmadi, Izzat; Shboul, Yazan

    2012-01-01

    In this research, a hybrid cost estimation model is proposed to produce a realistic prediction model that takes into consideration software project, product, process, and environmental elements. A cost estimation dataset is built from a large number of open source projects. Those projects are divided into three domains: communication, finance, and game projects. Several data mining techniques are used to classify software projects in terms of their development complexity. Data mining techniqu...

  12. Guidance and Control Software Project Data - Volume 2: Development Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the development documents from the GCS project. Volume 2 contains three appendices: A. Guidance and Control Software Development Specification; B. Design Description for the Pluto Implementation of the Guidance and Control Software; and C. Source Code for the Pluto Implementation of the Guidance and Control Software

  13. Large-scale visualization projects for teaching software engineering.

    Science.gov (United States)

    Müller, Christoph; Reina, Guido; Burch, Michael; Weiskopf, Daniel

    2012-01-01

    The University of Stuttgart's software engineering major complements the traditional computer science major with more practice-oriented education. Two-semester software projects in various application areas offered by the university's different computer science institutes are a successful building block in the curriculum. With this realistic, complex project setting, students experience the practice of software engineering, including software development processes, technologies, and soft skills. In particular, visualization-based projects are popular with students. Such projects offer them the opportunity to gain profound knowledge that would hardly be possible with only regular lectures and homework assignments.

  14. Methodology for economic evaluation of software development projects

    International Nuclear Information System (INIS)

    Witte, D.M.

    1990-01-01

    Many oil and gas exploration and production companies develop computer software in-house or with contract programmers to support their exploration activities. Software development projects compete for funding with exploration and development projects, though most companies lack valid comparison measures for the two types of projects. This paper presents a methodology of pro form a cash flow analysis for software development proposals intended for internal use. This methodology, based on estimates of development and support costs, exploration benefits, and probability of successful development and implementation, can be used to compare proposed software development projects directly with competing exploration proposals

  15. Guidance and Control Software Project Data - Volume 3: Verification Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

  16. Automating the management of software projects in a developing it ...

    African Journals Online (AJOL)

    Software project management is the control of the transformation of users' ... Model from The American Systems Corporation (ASC) was used for risk management. ... Multi-site development approach facilitates large projects by using simple ...

  17. FY95 software project management plan: TMACS, CASS computer systems

    International Nuclear Information System (INIS)

    Spurling, D.G.

    1994-01-01

    The FY95 Work Plan for TMACS and CASS Software Projects describes the activities planned for the current fiscal year. This plan replaces WHC-SD-WM-SDP-008. The TMACS project schedule is included in the TWRS Integrated Schedule

  18. Automating the management of software projects in a developing IT ...

    African Journals Online (AJOL)

    The resultant network-based software tool was developed on object-oriented technology using Java. The study established that good management practices may still be applied by the Nigerian software industry that lacks expertise in software management. Multi-site development approach facilitates large projects by using ...

  19. CVSgrab : Mining the History of Large Software Projects

    NARCIS (Netherlands)

    Voinea, S.L.; Telea, A.

    2006-01-01

    Many software projects use Software Configuration Management systems to support their development process. Such systems accumulate in time large amounts of information useful for process accounting and auditing. We study how software developers can get insight in this information in order to

  20. Good practices for educational software engineering projects

    NARCIS (Netherlands)

    van der Duim, Louwarnoud; Andersson, Jesper; Sinnema, Marco

    2007-01-01

    Recent publications indicate the importance of software engineering in the computer science curriculum. In this paper, we present the final part of software engineering education at University of Groningen in the Netherlands and Vaxjo University in Sweden, where student teams perform an industrial

  1. Designing Project Management for Global Software Development

    DEFF Research Database (Denmark)

    Tjørnehøj, Gitte; B. Balogh, Maria; Iversen, Cathrine

    2014-01-01

    of distributed software teams, based on a practice study and informed by well-known theories. Our work pinpoints the difficulties of handling the vital informal processes in distributed collaboration that are so vulnerable because the distances risk detaining their growth and increasing their decay rate......Software development in distributed teams remains challenging despite rapid technical improvement in tools for communication and collaboration across distance. The challenges stem from geographical, temporal and sociocultural distance and manifest themselves in a variety of difficulties...

  2. Identifying Coordination Problems in Software Development : Finding Mismatches between Software and Project Team Structures

    NARCIS (Netherlands)

    Amrit, Chintan Amrit; van Hillegersberg, Jos; Kumar, Kuldeep

    2012-01-01

    Today’s dynamic and iterative development environment brings significant challenges for software project management. In distributed project settings, “management by walking around” is no longer an option and project managers may miss out on key project insights. The TESNA (TEchnical Social Network

  3. OPTIMALISASI GITHUB UNTUK SOFTWARE PROJECT MANAGEMENT DENGAN MEMANFAATKAN NOTIFIKASI SMS

    Directory of Open Access Journals (Sweden)

    Syarif Hidayatulloh

    2016-03-01

    Full Text Available Abstract - software project management is the art and science of planning and supervision in software projects. On project management software many emerging constraints that could result in his development and software development. One of the key points in a project the software repository is the time it takes to comment on, add and merge source code. Rapid feedback to make the members of a software project team was pleased to contribute in a software project. Problems on Github repository is when the notification was delivered via the web and email are not directly addressed because the members of the project management software rarely check emails. The methods used in this study is a literature study and experiments of different cases in the article, book or paper that discusses how to implement project management software quality so the software project goals can be achieved. Conclusion the results of the research that has been done is to apply the SMS notification on Github is expected to further speed up the interaction and communication between members in a software project and makes it easier for an IT manager in conducting management on Github project. Keywords: Software project management, GitHub, notification, SMS Abstrak - Manajemen proyek Perangkat lunak adalah seni dan ilmu perencanaan dan pembimbingan dalam proyek perangkat lunak. Pada manajemen proyek perangkat lunak banyak muncul kendala-kendala yang dapat mengakibatkan lamanya pembangunan dan pengembangan perangkat lunak. Salah satu poin penting dalam sebuah repositori proyek perangkat lunak adalah waktu yang dibutuhkan untuk mengomentari, menambahkan dan menggabungkan source code. Feedback yang cepat membuat anggota-anggota tim proyek perangkat lunak merasa senang untuk berkontribusi dalam sebuah proyek perangkat lunak. Permasalahan pada repositori Github adalah ketika notifikasi yang disampaikan lewat web dan email tidak langsung ditanggapi karena anggota-anggota proyek

  4. Study on Risk Approaches in Software Development Projects

    Directory of Open Access Journals (Sweden)

    Claudiu BRANDAS

    2012-01-01

    Full Text Available Risk approaches in project development led to the integration in the IT project management methodologies and software development of activities and processes of risk management. The diversity and the advanced level of the used technologies in IT projects with increasing com-plexity leads to an exponential diversification of risk factors.The purpose of this research is to identify the level of the risk approach in IT projects both at the IT project management and software development methodologies level and the level of the perception of IT project man-agers, IT managers and IT analysts in Romanian IT companies. Thus, we want to determine the correlation between the use of a project management or software development methodology and the overall level of risk perceived by the project managers using these methodologies.

  5. Incorporating Gaming in Software Engineering Projects: Case of RMU Monopoly

    Directory of Open Access Journals (Sweden)

    Sushil Acharya

    2009-02-01

    Full Text Available A major challenge in engineering education is retaining student interest in the engineering discipline. Active student involvement in engineering projects is one way of retaining student interest. Such involvement can only be realized if project inception comes entirely from the student. This paper presents a software game, RMU Monopoly, developed as a project requirement for a software engineering course and describes the challenges and gains of implementing such a project. The RMU Monopoly was proposed by three junior software engineering students. The game is a multi-platform software program that allows up to eight players and implements the rules of the Monopoly board game. To ensure agility the game was developed using the spiral software development model. The Software Requirements Specification (SRS document was finalized through an iterative procedure. Standard Unified Modeling Language (UML diagrams were used for product design. A Risk Mitigation, Monitoring, and Management Plan (RMMM was developed to ensure proactive risk management. Gantt chart, weekly progress meetings and weekly scrum meetings were used to track project progress. C# and Sub- Version were used in a client-server architecture to develop the software. The project was successful in retaining student interest in the software engineering discipline

  6. Dynamic Capabilities and Project Management in Small Software Companies

    DEFF Research Database (Denmark)

    Nørbjerg, Jacob; Nielsen, Peter Axel; Persson, John Stouby

    2017-01-01

    A small software company depends on its capability to adapt to rapid technological and other changes in its environment—its dynamic capabilities. In this paper, we argue that to evolve and maintain its dynamic capabilities a small software company must pay attention to the interaction between...... dynamic capabilities at different levels of the company — particularly between the project management and the company levels. We present a case study of a small software company and show how successful dynamic capabilities at the company level can affect project management in small software companies...

  7. Regulation of ATM induction

    International Nuclear Information System (INIS)

    Clarke, R.A.; Fang, Z.M.; Kearsley, J.H.; Lee, C.S.; Sarris, M.; De Murrell, D.

    2000-01-01

    Full text: ATM, the tumour suppressor protein mutated in ataxia-telangiectasia, is of pivotal importance in controlling the cells primary response to ionising radiation (IR) induced DNA damage. Mutations in ATM which reduce the level of the ATM protein and/or compromise ATM functions are known to give rise to radiosensitivity and defective cell cycle checkpoint control. In response to DNA damage ATM kinase is rapidly activated and initiates downstream signalling to cell cycle control molecules including p53. To investigate additional mechanisms of ATM control we have employed ATM antisense expression in cultured cells, western analyses and immunohistochemistry in situ. We report that ATM can be up-regulated up to 10-fold following exposure to low levels of ionising radiation. ATM radiation-induction was radiation dose dependent while the rapidity of the response indicates a post translational pathway. The concurrent time frames for the radiation-induction of ATM levels and the activation of ATM kinase activity appear to be complimentary in boosting ATM's protective response to IR induced DNA damage, especially in ATM 'low expressing' systems. We also provide the first report of ATM misregulation in 2 cancer patients, indicating that ATM is not only radio-protective but has possible implications in cancer, particularly breast cancer. These results have particular importance in defining the regulation of the ATM protein as an: adaptive radio-response; radio-prognostic market in tumours and normal tissue, and breast cancer marker

  8. MEASUREMENT PROCESS OF SOFTWARE DEVELOPMENT PROJECTS FOR SUPPORTING STRATEGIC BUSINESS OBJECTIVES IN SOFTWARE DEVELOPING COMPANIES

    Directory of Open Access Journals (Sweden)

    Sandra Lais Pedroso

    2013-08-01

    Full Text Available Software developing companies work in a competitive market and are often challenged to make business decisions with impact on competitiveness. Models accessing maturity for software development processes quality, such as CMMI and MPS-BR, comprise process measurements systems (PMS. However, these models are not necessarily suitable to support business decisions, neither to achieve strategic goals. The objective of this work is to analyze how the PMS of software development projects could support business strategies for software developing companies. Results taken from this work show that PMS results from maturity models for software processes can be suited to help evaluating operating capabilities and supporting strategic business decisions.

  9. Software-based annunciator replacement: a tale of two projects

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, G.T., E-mail: simmongt@westinghouse.com [Westinghouse Electric Company LLC, Cranberry Township, PA (United States)

    2015-07-01

    Annunciator upgrade projects are often included as parts of operating plant life extension projects as the systems are old and replacement parts are difficult to source. This paper contains case studies of the software-based annunciator replacement projects at the Westinghouse SNUPPS training simulator in Pennsylvania and the Axpo Beznau nuclear power plant in Switzerland. Software-based annunciator systems can offer a number of feature enhancements including improved readability and operator awareness, easy configuration, alarm suppression features, and alarm management at operator workstations. This paper provides an overview of each project and discusses advantages, challenges, and lessons learned from both annunciator-replacement projects. (author)

  10. Software-based annunciator replacement: a tale of two projects

    International Nuclear Information System (INIS)

    Simmons, G.T.

    2015-01-01

    Annunciator upgrade projects are often included as parts of operating plant life extension projects as the systems are old and replacement parts are difficult to source. This paper contains case studies of the software-based annunciator replacement projects at the Westinghouse SNUPPS training simulator in Pennsylvania and the Axpo Beznau nuclear power plant in Switzerland. Software-based annunciator systems can offer a number of feature enhancements including improved readability and operator awareness, easy configuration, alarm suppression features, and alarm management at operator workstations. This paper provides an overview of each project and discusses advantages, challenges, and lessons learned from both annunciator-replacement projects. (author)

  11. Development and application of new quality model for software projects.

    Science.gov (United States)

    Karnavel, K; Dillibabu, R

    2014-01-01

    The IT industry tries to employ a number of models to identify the defects in the construction of software projects. In this paper, we present COQUALMO and its limitations and aim to increase the quality without increasing the cost and time. The computation time, cost, and effort to predict the residual defects are very high; this was overcome by developing an appropriate new quality model named the software testing defect corrective model (STDCM). The STDCM was used to estimate the number of remaining residual defects in the software product; a few assumptions and the detailed steps of the STDCM are highlighted. The application of the STDCM is explored in software projects. The implementation of the model is validated using statistical inference, which shows there is a significant improvement in the quality of the software projects.

  12. Software Schedules Missions, Aids Project Management

    Science.gov (United States)

    2008-01-01

    NASA missions require advanced planning, scheduling, and management, and the Space Agency has worked extensively to develop the programs and software suites necessary to facilitate these complex missions. These enormously intricate undertakings have hundreds of active components that need constant management and monitoring. It is no surprise, then, that the software developed for these tasks is often applicable in other high-stress, complex environments, like in government or industrial settings. NASA work over the past few years has resulted in a handful of new scheduling, knowledge-management, and research tools developed under contract with one of NASA s partners. These tools have the unique responsibility of supporting NASA missions, but they are also finding uses outside of the Space Program.

  13. The Fox Project: Advanced Development of Systems Software

    National Research Council Canada - National Science Library

    1999-01-01

    The long-term objectives of the Carnegie Mellon Fox Project are to improve the design and construction of systems software and to further the development of advanced programming language technology...

  14. The Fox Project: Advanced Development of Systems Software

    National Research Council Canada - National Science Library

    2000-01-01

    The long-term objectives of the Carnegie Mellon Fox Project are to improve the design and construction of systems software and to further the development of advanced programming language technology...

  15. Software metrics: The key to quality software on the NCC project

    Science.gov (United States)

    Burns, Patricia J.

    1993-01-01

    Network Control Center (NCC) Project metrics are captured during the implementation and testing phases of the NCCDS software development lifecycle. The metrics data collection and reporting function has interfaces with all elements of the NCC project. Close collaboration with all project elements has resulted in the development of a defined and repeatable set of metrics processes. The resulting data are used to plan and monitor release activities on a weekly basis. The use of graphical outputs facilitates the interpretation of progress and status. The successful application of metrics throughout the NCC project has been instrumental in the delivery of quality software. The use of metrics on the NCC Project supports the needs of the technical and managerial staff. This paper describes the project, the functions supported by metrics, the data that are collected and reported, how the data are used, and the improvements in the quality of deliverable software since the metrics processes and products have been in use.

  16. Exploring the Role of Social Software in Global Software Development Projects

    DEFF Research Database (Denmark)

    Giuffrida, Rosalba; Dittrich, Y.

    2011-01-01

    We present a PhD project that investigates the use of Social Software (SoSo) in Global Software Development (GSD) teams. Since SoSo in unstructured and informal in its own nature, we explore how informal communication, which is challenging in GSD, is supported by SoSo in distributed teams and how...

  17. Measurement of Software Project Management Effectiveness

    Science.gov (United States)

    2008-12-01

    factors such as advertisement of project mission, top management support, client consultation, personnel issues, client acceptance, etc. Trouble...and PERT (Program/Project Evaluation and Review Technique) and CPM (Critical Path Analysis) charts are process models, and the development of Gantt...models (such as Gantt, PERT and CPM ) got wide-acceptance in industry, as Fuggetta (2000) pointed out few (if any) of the proposed PMLs and related

  18. Coordinating Management Activities in Distributed Software Development Projects

    OpenAIRE

    Bendeck, Fawsy; Goldmann, Sigrid; Holz, Harald; Kötting, Boris

    1999-01-01

    Coordinating distributed processes, especially engineering and software design processes, has been a research topic for some time now. Several approaches have been published that aim at coordinating large projects in general, and large software development processes in specific. However, most of these approaches focus on the technical part of the design process and omit management activities like planning and scheduling the project, or monitoring it during execution. In this paper, we focus o...

  19. Framework for Small-Scale Experiments in Software Engineering: Guidance and Control Software Project: Software Engineering Case Study

    Science.gov (United States)

    Hayhurst, Kelly J.

    1998-01-01

    Software is becoming increasingly significant in today's critical avionics systems. To achieve safe, reliable software, government regulatory agencies such as the Federal Aviation Administration (FAA) and the Department of Defense mandate the use of certain software development methods. However, little scientific evidence exists to show a correlation between software development methods and product quality. Given this lack of evidence, a series of experiments has been conducted to understand why and how software fails. The Guidance and Control Software (GCS) project is the latest in this series. The GCS project is a case study of the Requirements and Technical Concepts for Aviation RTCA/DO-178B guidelines, Software Considerations in Airborne Systems and Equipment Certification. All civil transport airframe and equipment vendors are expected to comply with these guidelines in building systems to be certified by the FAA for use in commercial aircraft. For the case study, two implementations of a guidance and control application were developed to comply with the DO-178B guidelines for Level A (critical) software. The development included the requirements, design, coding, verification, configuration management, and quality assurance processes. This paper discusses the details of the GCS project and presents the results of the case study.

  20. The Dark Side of Software Engineering Evil on Computing Projects

    CERN Document Server

    Rost, Johann

    2010-01-01

    Betrayal! Corruption! Software engineering? Industry experts Johann Rost and Robert L. Glass explore the seamy underbelly of software engineering in this timely report on and analysis of the prevalance of subversion, lying, hacking, and espionage on every level of software project management. Based on the authors' original research and augmented by frank discussion and insights from other well-respected figures, The Dark Side of Software Engineering goes where other management studies fear to tread -- a corporate environment where schedules are fabricated, trust is betrayed, millions of dollar

  1. Methods for cost estimation in software project management

    Science.gov (United States)

    Briciu, C. V.; Filip, I.; Indries, I. I.

    2016-02-01

    The speed in which the processes used in software development field have changed makes it very difficult the task of forecasting the overall costs for a software project. By many researchers, this task has been considered unachievable, but there is a group of scientist for which this task can be solved using the already known mathematical methods (e.g. multiple linear regressions) and the new techniques as genetic programming and neural networks. The paper presents a solution for building a model for the cost estimation models in the software project management using genetic algorithms starting from the PROMISE datasets related COCOMO 81 model. In the first part of the paper, a summary of the major achievements in the research area of finding a model for estimating the overall project costs is presented together with the description of the existing software development process models. In the last part, a basic proposal of a mathematical model of a genetic programming is proposed including here the description of the chosen fitness function and chromosome representation. The perspective of model described it linked with the current reality of the software development considering as basis the software product life cycle and the current challenges and innovations in the software development area. Based on the author's experiences and the analysis of the existing models and product lifecycle it was concluded that estimation models should be adapted with the new technologies and emerging systems and they depend largely by the chosen software development method.

  2. IT Project Management in Very Small Software Companies

    DEFF Research Database (Denmark)

    Shakir, Shahid Nadeem; Nørbjerg, Jacob

    2013-01-01

    In developing countries very small software companies (VSSCs) with only 1-10 employees play an important role both in the local economy and as providers of software and services to customers in other parts of the world. Understanding and improving their IT project management (ITPM) practices...... and challenges are, therefore, important in the local as well as the larger context of globalized software development. There is, however, very little research into small shop software practices in developing countries. The current paper explores actual ITPM practices in Pakistani VSSCs based on a qualitative...... study of seven Pakistani VSSCs. We find that some Pakistani ITPM practices are similar to what is reported from VSSCs in other parts of the world, while others seem to be related to the companies' position in the global software development chain. This paper is part of a larger research project aiming...

  3. ATM and Internet protocol

    CERN Document Server

    Bentall, M; Turton, B

    1998-01-01

    Asynchronous Transfer Mode (ATM) is a protocol that allows data, sound and video being transferred between independent networks via ISDN links to be supplied to, and interpreted by, the various system protocols.ATM and Internet Protocol explains the working of the ATM and B-ISDN network for readers with a basic understanding of telecommunications. It provides a handy reference to everyone working with ATM who may not require the full standards in detail, but need a comprehensive guide to ATM. A substantial section is devoted to the problems of running IP over ATM and there is some discussion o

  4. Software Support for the Classical, Contemporary and Future Project Management

    Directory of Open Access Journals (Sweden)

    Jakov Crnkovic

    2006-04-01

    Full Text Available The volume and complexity of Project Management (PM raises many questions for managers. What exactly are we managing? People? Performance? Efficiency? Effectiveness? Cost? Time? At what levels do projects become challenging and worthy of significant management attention? Can some projects be left on auto-pilot? Must others be managed more aggressively? What metrics are useful in Project Management? How can they be integrated with normal performance metrics in the organization? How can metrics be built into assessment programs that work? How can projects be monitored, re-planned to stay within the original budget and schedule deadlines? How good is the PM software support? Do we really need PM software packages or it should be the integral part of the company's information system (IS? Where is the knowledge about company's previous projects and performance? Are we able to establish company or even industry wide standards for project management? Can we (or should we move from the PMBOK® guidelines and use other approaches? We discussing important questions in PM: software products, responsibilities for concurrently executing several projects (multi-projects with multi objectives and multiple deadlines, introducing a need for initiation, design, execution, and control using a virtual project management and application of the organizational project maturity model.

  5. A Project Management Approach to Using Simulation for Cost Estimation on Large, Complex Software Development Projects

    Science.gov (United States)

    Mizell, Carolyn; Malone, Linda

    2007-01-01

    It is very difficult for project managers to develop accurate cost and schedule estimates for large, complex software development projects. None of the approaches or tools available today can estimate the true cost of software with any high degree of accuracy early in a project. This paper provides an approach that utilizes a software development process simulation model that considers and conveys the level of uncertainty that exists when developing an initial estimate. A NASA project will be analyzed using simulation and data from the Software Engineering Laboratory to show the benefits of such an approach.

  6. Support for Different Roles in Software Engineering Master's Thesis Projects

    Science.gov (United States)

    Host, M.; Feldt, R.; Luders, F.

    2010-01-01

    Like many engineering programs in Europe, the final part of most Swedish software engineering programs is a longer project in which the students write a Master's thesis. These projects are often conducted in cooperation between a university and industry, and the students often have two supervisors, one at the university and one in industry. In…

  7. A Team Building Model for Software Engineering Courses Term Projects

    Science.gov (United States)

    Sahin, Yasar Guneri

    2011-01-01

    This paper proposes a new model for team building, which enables teachers to build coherent teams rapidly and fairly for the term projects of software engineering courses. Moreover, the model can also be used to build teams for any type of project, if the team member candidates are students, or if they are inexperienced on a certain subject. The…

  8. Open Crowdsourcing: Leveraging Community Software Developers for IT Projects

    Science.gov (United States)

    Phair, Derek

    2012-01-01

    This qualitative exploratory single-case study was designed to examine and understand the use of volunteer community participants as software developers and other project related roles, such as testers, in completing a web-based application project by a non-profit organization. This study analyzed the strategic decision to engage crowd…

  9. Metrics-based control in outsourced software development projects

    NARCIS (Netherlands)

    Ponisio, Laura; van Eck, Pascal

    2012-01-01

    Measurements have been recognised as vital instruments to improve control in outsourced software development projects. However, project managers are still struggling with the design and implementation of effective measurement programs. One reason for this is that although there is a large body of

  10. Open Source Projects in Software Engineering Education: A Mapping Study

    Science.gov (United States)

    Nascimento, Debora M. C.; Almeida Bittencourt, Roberto; Chavez, Christina

    2015-01-01

    Context: It is common practice in academia to have students work with "toy" projects in software engineering (SE) courses. One way to make such courses more realistic and reduce the gap between academic courses and industry needs is getting students involved in open source projects (OSP) with faculty supervision. Objective: This study…

  11. Introduction to Financial Projection Models. Business Management Instructional Software.

    Science.gov (United States)

    Pomeroy, Robert W., III

    This guidebook and teacher's guide accompany a personal computer software program and introduce the key elements of financial projection modeling to project the financial statements of an industrial enterprise. The student will then build a model on an electronic spreadsheet. The guidebook teaches the purpose of a financial model and the steps…

  12. QFD Application to a Software - Intensive System Development Project

    Science.gov (United States)

    Tran, T. L.

    1996-01-01

    This paper describes the use of Quality Function Deployment (QFD), adapted to requirements engineering for a software-intensive system development project, and sysnthesizes the lessons learned from the application of QFD to the Network Control System (NCS) pre-project of the Deep Space Network.

  13. Integrating HCI Specialists into Open Source Software Development Projects

    Science.gov (United States)

    Hedberg, Henrik; Iivari, Netta

    Typical open source software (OSS) development projects are organized around technically talented developers, whose communication is based on technical aspects and source code. Decision-making power is gained through proven competence and activity in the project, and non-technical end-user opinions are too many times neglected. In addition, also human-computer interaction (HCI) specialists have encountered difficulties in trying to participate in OSS projects, because there seems to be no clear authority and responsibility for them. In this paper, based on HCI and OSS literature, we introduce an extended OSS development project organization model that adds a new level of communication and roles for attending human aspects of software. The proposed model makes the existence of HCI specialists visible in the projects, and promotes interaction between developers and the HCI specialists in the course of a project.

  14. ATM technology and beyond

    Science.gov (United States)

    Cheung, Nim K.

    1993-01-01

    Networks based on Asynchronous Transfer Mode (ATM) are expected to provide cost-effective and ubiquitous infrastructure to support broadband and multimedia services. In this paper, we give an overview of the ATM standards and its associated physical layer transport technologies. We use the experimental HIPPI-ATM-SONET (HAS) interface in the Nectar Gigabit Testbed to illustrate how one can use the SONET/ATM public network to provide transport for bursty gigabit applications.

  15. How Social Software Supports Cooperative Practices in a Globally Distributed Software Project

    DEFF Research Database (Denmark)

    Giuffrida, Rosalba; Dittrich, Yvonne

    2014-01-01

    In Global Software Development (GSD), the lack of face- to-face communication is a major challenge and effective computer-mediated practices are necessary. This paper analyzes cooperative practices supported by Social Software (SoSo) in a GSD student project. The empirical results show...... that the role of SoSo is to support informal communication, enabling social talks and metawork, both necessary for establishing and for maintaining effective coordination mechanisms, thus successful cooperation....

  16. Managing Risks in Distributed Software Projects: An Integrative Framework

    DEFF Research Database (Denmark)

    Persson, John Stouby; Mathiassen, Lars; Boeg, Jesper

    2009-01-01

    techniques into an integrative framework for managing risks in distributed contexts. Subsequent implementation of a Web-based tool helped us refine the framework based on empirical evaluation of its practical usefulness.We conclude by discussing implications for both research and practice.......Software projects are increasingly geographically distributed with limited face-to-face interaction between participants. These projects face particular challenges that need carefulmanagerial attention. While risk management has been adopted with success to address other challenges within software...... development, there are currently no frameworks available for managing risks related to geographical distribution. On this background, we systematically review the literature on geographically distributed software projects. Based on the review, we synthesize what we know about risks and risk resolution...

  17. The dynamic of modern software development project management and the software crisis of quality. An integrated system dynamics approach towards software quality improvement

    OpenAIRE

    Nasirikaljahi, Armindokht

    2012-01-01

    The software industry is plagued by cost-overruns, delays, poor customer satisfaction and quality issues that are costing clients and customers world-wide billions of dollars each year. The phenomenon is coined The Software Crisis", and poses a huge challenge for software project management. This thesis addresses one of the core issues of the software crisis, namely software quality. The challenges of software quality are central for understanding the other symptoms of the software crisis. Th...

  18. A Managerial Analysis of ATM in Facilitating Distance Education.

    Science.gov (United States)

    Littman, Marlyn Kemper

    In this paper, the fundamental characteristics and capabilities of ATM (Asynchronous Transfer Mode) networks in a distance learning environment are examined. Current and projected ATM applications are described, and issues and challenges associated with developing ATM networking solutions for instructional delivery are explored. Other topics…

  19. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  20. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    International Nuclear Information System (INIS)

    Fishler, B.

    2011-01-01

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  1. REVIEW ON CONSTRUCTION PROJECT MANAGEMENT SOFTWARE PRIMAVERA P6

    OpenAIRE

    Piyush Pramod Bagade* & Prof. Abhijit Bhirud

    2018-01-01

    Planning, scheduling and Resource levelling plays an important role in any construction project maybe it is construction of building or construction of road. In absence of proper planning, scheduling and resource levelling construction industry does not get profit over the project. For this purpose, proper software’s and techniques must be utilize. This paper is focussing on the advantages of Oracle Primavera P6 Software. The latest version of Primavera is P6-17. In any construction work huge...

  2. An Assessment of risk response strategies practiced in software projects

    Directory of Open Access Journals (Sweden)

    Vanita Bhoola

    2014-11-01

    Full Text Available Risk management and success in projects are highly intertwined – better approaches to project risk management tend to increase chances of project success in terms of achieving scope & quality, schedule and cost targets. The process of responding to risk factors during a project’s life cycle is a crucial aspect of risk management referred to as risk response strategies, in this paper. The current research explores the status of risk response strategies applied in the software development projects in India. India provides a young IT-savvy English-speaking population, which is also cost effective. Other than the workforce, the environment for implementation of software projects in India is different from the matured economies. Risk management process is a commonly discussed theme, though its implementation in practice has a huge scope for improvement in India. The paper talks about four fundamental treatments to risk response – Avoidance, Transference, Mitigation and Acceptance (ATMA. From a primary data of 302 project managers, the paper attempts to address the risk response factors that lead to successful achievement of project scope & quality, schedule and cost targets, by using a series of regressions followed with Seemingly Unrelated Regression Equations (SURE modelling. Mitigation emerged as the most significant risk response strategy to achieve project targets. Acceptance, transference, and avoidance of risk were mostly manifested in the forms of transparency in communication across stakeholders, careful study of the nature of risks and close coordination between project team, customers/end-users and top management.

  3. The Company Approach to Software Engineering Project Courses

    Science.gov (United States)

    Broman, D.; Sandahl, K.; Abu Baker, M.

    2012-01-01

    Teaching larger software engineering project courses at the end of a computing curriculum is a way for students to learn some aspects of real-world jobs in industry. Such courses, often referred to as capstone courses, are effective for learning how to apply the skills they have acquired in, for example, design, test, and configuration management.…

  4. Enhancing the Student Learning Experience in Software Engineering Project Courses

    Science.gov (United States)

    Marques, Maira; Ochoa, Sergio F.; Bastarrica, Maria Cecilia; Gutierrez, Francisco J.

    2018-01-01

    Carrying out real-world software projects in their academic studies helps students to understand what they will face in industry, and to experience first-hand the challenges involved when working collaboratively. Most of the instructional strategies used to help students take advantage of these activities focus on supporting agile programming,…

  5. Coordination and Control of Globally Distributed Software Projects

    NARCIS (Netherlands)

    P.C. van Fenema (Paul)

    2002-01-01

    textabstractRecently, software development and implementation projects have globalized at a rapid pace. Companies in North America, Europe, and the Far East are beginning to integrate international Information Technology (IT) resources to support operations across the globe. Offshore IT services

  6. Software quality assurance on the Yucca Mountain Site Characterization Project

    International Nuclear Information System (INIS)

    Matras, J.R.

    1993-01-01

    The Yucca Mountain Site Characterization Project (YMP) has been involved over the years in the continuing struggle with establishing acceptable Software Quality Assurance (SQA) requirements for the development, modification, and acquisition of computer programs used to support the Mined Geologic Disposal System. These computer programs will be used to produce or manipulate data used directly in site characterization, design, analysis, performance assessment, and operation of repository structures, systems, and components. Scientists and engineers working on the project have claimed that the SQA requirements adopted by the project are too restrictive to allow them to perform their work. This paper will identify the source of the original SQA requirements adopted by the project. It will delineate the approach used by the project to identify concerns voiced by project engineers and scientists regarding the original SQA requirements. It will conclude with a discussion of methods used to address these problems in the rewrite of the original SQA requirements

  7. Sustainable Software Decisions for Long-term Projects (Invited)

    Science.gov (United States)

    Shepherd, A.; Groman, R. C.; Chandler, C. L.; Gaylord, D.; Sun, M.

    2013-12-01

    Adopting new, emerging technologies can be difficult for established projects that are positioned to exist for years to come. In some cases the challenge lies in the pre-existing software architecture. In others, the challenge lies in the fluctuation of resources like people, time and funding. The Biological and Chemical Oceanography Data Management Office (BCO-DMO) was created in late 2006 by combining the data management offices for the U.S. GLOBEC and U.S. JGOFS programs to publish data for researchers funded by the National Science Foundation (NSF). Since its inception, BCO-DMO has been supporting access and discovery of these data through web-accessible software systems, and the office has worked through many of the challenges of incorporating new technologies into its software systems. From migrating human readable, flat file metadata storage into a relational database, and now, into a content management system (Drupal) to incorporating controlled vocabularies, new technologies can radically affect the existing software architecture. However, through the use of science-driven use cases, effective resource management, and loosely coupled software components, BCO-DMO has been able to adapt its existing software architecture to adopt new technologies. One of the latest efforts at BCO-DMO revolves around applying metadata semantics for publishing linked data in support of data discovery. This effort primarily affects the metadata web interface software at http://bco-dmo.org and the geospatial interface software at http://mapservice.bco-dmo.org/. With guidance from science-driven use cases and consideration of our resources, implementation decisions are made using a strategy to loosely couple the existing software systems to the new technologies. The results of this process led to the use of REST web services and a combination of contributed and custom Drupal modules for publishing BCO-DMO's content using the Resource Description Framework (RDF) via an instance of

  8. Dedicated OO expertise applied to Run II software projects

    International Nuclear Information System (INIS)

    Amidei, D.

    2000-01-01

    The change in software language and methodology by CDF and D0 to object-oriented from procedural Fortran is significant. Both experiments requested dedicated expertise that could be applied to software design, coding, advice and review. The Fermilab Run II offline computing outside review panel agreed strongly with the request and recommended that the Fermilab Computing Division hire dedicated OO expertise for the CDF/D0/Computing Division joint project effort. This was done and the two experts have been an invaluable addition to the CDF and D0 upgrade software projects and to the Computing Division in general. These experts have encouraged common approaches and increased the overall quality of the upgrade software. Advice on OO techniques and specific advice on C++ coding has been used. Recently a set of software reviews has been accomplished. This has been a very successful instance of a targeted application of computing expertise, and constitutes a very interesting study of how to move toward modern computing methodologies in HEP

  9. Software project management tools in global software development: a systematic mapping study.

    Science.gov (United States)

    Chadli, Saad Yasser; Idri, Ali; Ros, Joaquín Nicolás; Fernández-Alemán, José Luis; de Gea, Juan M Carrillo; Toval, Ambrosio

    2016-01-01

    Global software development (GSD) which is a growing trend in the software industry is characterized by a highly distributed environment. Performing software project management (SPM) in such conditions implies the need to overcome new limitations resulting from cultural, temporal and geographic separation. The aim of this research is to discover and classify the various tools mentioned in literature that provide GSD project managers with support and to identify in what way they support group interaction. A systematic mapping study has been performed by means of automatic searches in five sources. We have then synthesized the data extracted and presented the results of this study. A total of 102 tools were identified as being used in SPM activities in GSD. We have classified these tools, according to the software life cycle process on which they focus and how they support the 3C collaboration model (communication, coordination and cooperation). The majority of the tools found are standalone tools (77%). A small number of platforms (8%) also offer a set of interacting tools that cover the software development lifecycle. Results also indicate that SPM areas in GSD are not adequately supported by corresponding tools and deserve more attention from tool builders.

  10. Computing with words to feasibility study of software projects

    Directory of Open Access Journals (Sweden)

    Marieta Peña Abreu

    2017-02-01

    Full Text Available Objective: This paper proposes a method to analyze the technical, commercial and social feasibility of software projects in environments of uncertainty. It allows working with multiple experts and multiple criteria and facilitates decision-making. Method: The proposal contains two phases, first the necessary information is collected and in second place projects are evaluated using 2-tuple linguistic representation model. The experts are selected by analyzing their curricular synthesis. The evaluation criteria are defined using the technique Focus Group and weighted in the interval (0,1 according to their importance. three domains are offered to express the preferences: numeric, interval-valued and linguistic. For aggregation extended arithmetic mean and weighted average extended are used, preventing the loss of information. A 2-tuple (feasibility, precision is obtained as a result for each project. Results: The evaluation of P1 project was a very high feasibility with -0,33 of precision. The P2 project obtained a high feasibility with 0,38 of precision and P3 project achieved a medium feasibility with -0,21 of precision. Conclusions: This method is favorable for software projects feasibility analysis with presence of multiple experts and criteria, in environments of uncertainty. It tries heterogeneous assessments without loss of information. Their results are consistent and useful for decision makers.

  11. Modern software approaches applied to a Hydrological model: the GEOtop Open-Source Software Project

    Science.gov (United States)

    Cozzini, Stefano; Endrizzi, Stefano; Cordano, Emanuele; Bertoldi, Giacomo; Dall'Amico, Matteo

    2017-04-01

    The GEOtop hydrological scientific package is an integrated hydrological model that simulates the heat and water budgets at and below the soil surface. It describes the three-dimensional water flow in the soil and the energy exchange with the atmosphere, considering the radiative and turbulent fluxes. Furthermore, it reproduces the highly non-linear interactions between the water and energy balance during soil freezing and thawing, and simulates the temporal evolution of snow cover, soil temperature and moisture. The core components of the package were presented in the 2.0 version (Endrizzi et al, 2014), which was released as Free Software Open-source project. However, despite the high scientific quality of the project, a modern software engineering approach was still missing. Such weakness hindered its scientific potential and its use both as a standalone package and, more importantly, in an integrate way with other hydrological software tools. In this contribution we present our recent software re-engineering efforts to create a robust and stable scientific software package open to the hydrological community, easily usable by researchers and experts, and interoperable with other packages. The activity takes as a starting point the 2.0 version, scientifically tested and published. This version, together with several test cases based on recent published or available GEOtop applications (Cordano and Rigon, 2013, WRR, Kollet et al, 2016, WRR) provides the baseline code and a certain number of referenced results as benchmark. Comparison and scientific validation can then be performed for each software re-engineering activity performed on the package. To keep track of any single change the package is published on its own github repository geotopmodel.github.io/geotop/ under GPL v3.0 license. A Continuous Integration mechanism by means of Travis-CI has been enabled on the github repository on master and main development branches. The usage of CMake configuration tool

  12. Experience Report: Introducing Kanban Into Automotive Software Project

    Directory of Open Access Journals (Sweden)

    Marek Majchrzak

    2017-03-01

    Full Text Available The boundaries between traditional and agile approach methods are disappearing. A significant number of software projects require a continuous implementation of tasks without dividing them into sprints or strict project phases. Customers expect more flexibility and responsiveness from software vendors in response to the ever-changing business environment. To achieve better results in this field, Capgemini has begun using the Lean philosophy and Kanban techniques. \\\\The following article illustrates examples of different uses of Kanban and the main stakeholder of the process. The article presents the main advantages of transparency and ways to improve the customer co-operation as well as stakeholder relationships. The Authors try to visualise all of the elements in the context of the project. \\\\There is also a discussion of different approaches in two software projects. The article fokuses on the main challenges and the evolutionary approach used. An attempt is made to answer the question how to convince both the team as well as the customer, and how to optimise ways to achieve great results.

  13. Management Guidelines for Database Developers' Teams in Software Development Projects

    Science.gov (United States)

    Rusu, Lazar; Lin, Yifeng; Hodosi, Georg

    Worldwide job market for database developers (DBDs) is continually increasing in last several years. In some companies, DBDs are organized as a special team (DBDs team) to support other projects and roles. As a new role, the DBDs team is facing a major problem that there are not any management guidelines for them. The team manager does not know which kinds of tasks should be assigned to this team and what practices should be used during DBDs work. Therefore in this paper we have developed a set of management guidelines, which includes 8 fundamental tasks and 17 practices from software development process, by using two methodologies Capability Maturity Model (CMM) and agile software development in particular Scrum in order to improve the DBDs team work. Moreover the management guidelines developed here has been complemented with practices from authors' experience in this area and has been evaluated in the case of a software company. The management guidelines for DBD teams presented in this paper could be very usefully for other companies too that are using a DBDs team and could contribute towards an increase of the efficiency of these teams in their work on software development projects.

  14. Self-service for software development projects and HPC activities

    International Nuclear Information System (INIS)

    Husejko, M; Høimyr, N; Gonzalez, A; Koloventzos, G; Asbury, D; Trzcinska, A; Agtzidis, I; Botrel, G; Otto, J

    2014-01-01

    This contribution describes how CERN has implemented several essential tools for agile software development processes, ranging from version control (Git) to issue tracking (Jira) and documentation (Wikis). Running such services in a large organisation like CERN requires many administrative actions both by users and service providers, such as creating software projects, managing access rights, users and groups, and performing tool-specific customisation. Dealing with these requests manually would be a time-consuming task. Another area of our CERN computing services that has required dedicated manual support has been clusters for specific user communities with special needs. Our aim is to move all our services to a layered approach, with server infrastructure running on the internal cloud computing infrastructure at CERN. This contribution illustrates how we plan to optimise the management of our of services by means of an end-user facing platform acting as a portal into all the related services for software projects, inspired by popular portals for open-source developments such as Sourceforge, GitHub and others. Furthermore, the contribution will discuss recent activities with tests and evaluations of High Performance Computing (HPC) applications on different hardware and software stacks, and plans to offer a dynamically scalable HPC service at CERN, based on affordable hardware.

  15. SNL software manual for the ACS Data Analytics Project.

    Energy Technology Data Exchange (ETDEWEB)

    Stearley, Jon R.; McLendon, William Clarence, III; Rodrigues, Arun F.; Williams, Aaron S.; Hooper, Russell Warren; Robinson, David Gerald; Stickland, Michael G.

    2011-10-01

    In the ACS Data Analytics Project (also known as 'YumYum'), a supercomputer is modeled as a graph of components and dependencies, jobs and faults are simulated, and component fault rates are estimated using the graph structure and job pass/fail outcomes. This report documents the successful completion of all SNL deliverables and tasks, describes the software written by SNL for the project, and presents the data it generates. Readers should understand what the software tools are, how they fit together, and how to use them to reproduce the presented data and additional experiments as desired. The SNL YumYum tools provide the novel simulation and inference capabilities desired by ACS. SNL also developed and implemented a new algorithm, which provides faster estimates, at finer component granularity, on arbitrary directed acyclic graphs.

  16. A Data Specification for Software Project Performance Measures: Results of a Collaboration on Performance Measurement

    National Research Council Canada - National Science Library

    Kasunic, Mark

    2008-01-01

    ... between completed projects. These terms and definitions were developed using a collaborative, consensus-based approach involving the Software Engineering Institute's Software Engineering Process Management program and service...

  17. The software analysis project for the Office of Human Resources

    Science.gov (United States)

    Tureman, Robert L., Jr.

    1994-01-01

    There were two major sections of the project for the Office of Human Resources (OHR). The first section was to conduct a planning study to analyze software use with the goal of recommending software purchases and determining whether the need exists for a file server. The second section was analysis and distribution planning for retirement planning computer program entitled VISION provided by NASA Headquarters. The software planning study was developed to help OHR analyze the current administrative desktop computing environment and make decisions regarding software acquisition and implementation. There were three major areas addressed by the study: current environment new software requirements, and strategies regarding the implementation of a server in the Office. To gather data on current environment, employees were surveyed and an inventory of computers were produced. The surveys were compiled and analyzed by the ASEE fellow with interpretation help by OHR staff. New software requirements represented a compilation and analysis of the surveyed requests of OHR personnel. Finally, the information on the use of a server represents research done by the ASEE fellow and analysis of survey data to determine software requirements for a server. This included selection of a methodology to estimate the number of copies of each software program required given current use and estimated growth. The report presents the results of the computing survey, a description of the current computing environment, recommenations for changes in the computing environment, current software needs, management advantages of using a server, and management considerations in the implementation of a server. In addition, detailed specifications were presented for the hardware and software recommendations to offer a complete picture to OHR management. The retirement planning computer program available to NASA employees will aid in long-range retirement planning. The intended audience is the NASA civil

  18. Software project estimation the fundamentals for providing high quality information to decision makers

    CERN Document Server

    Abran, Alain

    2015-01-01

    Software projects are often late and over-budget and this leads to major problems for software customers. Clearly, there is a serious issue in estimating a realistic, software project budget. Furthermore, generic estimation models cannot be trusted to provide credible estimates for projects as complex as software projects. This book presents a number of examples using data collected over the years from various organizations building software. It also presents an overview of the non-for-profit organization, which collects data on software projects, the International Software Benchmarking Stan

  19. The Role of Requirements in the Success or Failure of Software Projects

    OpenAIRE

    Hussain, Azham; Mkpojiogu, Emmanuel O.C.; Kamal, Fazillah Mohmad

    2016-01-01

    Requirements engineering is pivotal and central to every successful software development project. There are several reasons why software projects fail; however, poorly elicited, documented, validated and managed requirements contribute grossly to software projects failure. Software project failures are normally very costly and risky and these could even a times be life threatening also. Projects that overlook requirements engineering processes often suffer or are most likely to suffer from fa...

  20. Software use cases to elicit the software requirements analysis within the ASTRI project

    Science.gov (United States)

    Conforti, Vito; Antolini, Elisa; Bonnoli, Giacomo; Bruno, Pietro; Bulgarelli, Andrea; Capalbi, Milvia; Fioretti, Valentina; Fugazza, Dino; Gardiol, Daniele; Grillo, Alessandro; Leto, Giuseppe; Lombardi, Saverio; Lucarelli, Fabrizio; Maccarone, Maria Concetta; Malaguti, Giuseppe; Pareschi, Giovanni; Russo, Federico; Sangiorgi, Pierluca; Schwarz, Joseph; Scuderi, Salvatore; Tanci, Claudio; Tosti, Gino; Trifoglio, Massimo; Vercellone, Stefano; Zanmar Sanchez, Ricardo

    2016-07-01

    The Italian National Institute for Astrophysics (INAF) is leading the Astrofisica con Specchi a Tecnologia Replicante Italiana (ASTRI) project whose main purpose is the realization of small size telescopes (SST) for the Cherenkov Telescope Array (CTA). The first goal of the ASTRI project has been the development and operation of an innovative end-to-end telescope prototype using a dual-mirror optical configuration (SST-2M) equipped with a camera based on silicon photo-multipliers and very fast read-out electronics. The ASTRI SST-2M prototype has been installed in Italy at the INAF "M.G. Fracastoro" Astronomical Station located at Serra La Nave, on Mount Etna, Sicily. This prototype will be used to test several mechanical, optical, control hardware and software solutions which will be used in the ASTRI mini-array, comprising nine telescopes proposed to be placed at the CTA southern site. The ASTRI mini-array is a collaborative and international effort led by INAF and carried out by Italy, Brazil and South-Africa. We present here the use cases, through UML (Unified Modeling Language) diagrams and text details, that describe the functional requirements of the software that will manage the ASTRI SST-2M prototype, and the lessons learned thanks to these activities. We intend to adopt the same approach for the Mini Array Software System that will manage the ASTRI miniarray operations. Use cases are of importance for the whole software life cycle; in particular they provide valuable support to the validation and verification activities. Following the iterative development approach, which breaks down the software development into smaller chunks, we have analysed the requirements, developed, and then tested the code in repeated cycles. The use case technique allowed us to formalize the problem through user stories that describe how the user procedurally interacts with the software system. Through the use cases we improved the communication among team members, fostered

  1. Inequalities in Open Source Software Development: Analysis of Contributor's Commits in Apache Software Foundation Projects.

    Science.gov (United States)

    Chełkowski, Tadeusz; Gloor, Peter; Jemielniak, Dariusz

    2016-01-01

    While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution.

  2. PROJECT-DRIVEN SOFTWARE BUSINESS IN TRANSILVANIA - A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Radu Marius

    2015-07-01

    Full Text Available The fairly low salaries of the IT workers compared to the Western countries, the skills and the location have supported outsourcing become one of the most competitive Romanian sectors. IT sector in Romania maintains a steady growth favoured by outsourcing companies. Moreover Romania is highly competitive when you take into account the level of technical proficiency and soft skills in the country. Romanian labour force can drive relevant projects even in small teams. This case study explores the realty of Romanian IT companies profiles. It presents in comparison two companies bases on organizational and strategic dimensions: project approach orientation, leadership, project value driven, and social responsibility. The corporate goal of the first company presented in the case study - Fortech - is to achieve the best adaptive organizational structure which can sustain its competitive advantage. This advantage results from combination of three main ingredients: scaled up human resource capital, versatile knowledge management and adaptability to customer needs. Fortech manages and administrates and execute their business activities using project management methodologies and practices in order to achieve the strategic goals. On the other hand Dolphin Kiss Company is a “Python boutique agency” created around a single contract and organized on a single project. The project was contracted with a top company from telecommunication industry. The company is a small team of creative software engineers focused on developing a very innovative software business solution. This case study is an empirical qualitative research intended to depict the main differences between two relevant company profiles present in the actual economic context: small team – results oriented – highly skilled VS large structure of outsourcing teams – matrix organized – customer oriented. The case study constructs a space for debates regarding the potential evolution of the

  3. Hierarchy Software Development Framework (h-dp-fwk) project

    International Nuclear Information System (INIS)

    Zaytsev, A

    2010-01-01

    Hierarchy Software Development Framework provides a lightweight tool for building portable modular applications for performing automated data analysis tasks in a batch mode. The history of design and development activities devoted to the project has begun in March 2005 and from the very beginning it was targeting the case of building experimental data processing applications for the CMD-3 experiment which is being commissioned at Budker Institute of Nuclear Physics (BINP, Novosibirsk, Russia). Its design addresses the generic case of modular data processing application operating within the well defined distributed computing environment. The main features of the framework are modularity, built-in message and data exchange mechanisms, XInclude and XML schema enabled XML configuration management tools, dedicated log management tools, internal debugging tools, both dynamic and static module chains support, internal DSO version and consistency checking, well defined API for developing specialized frameworks. It is supported on Scientific Linux 4 and 5 and planned to be ported to other platforms as well. The project is provided with the comprehensive set of technical documentation and users' guides. The licensing schema for the source code, binaries and documentation implies that the product is free for non-commercial use. Although the development phase is not over and many features are to be implemented yet the project is considered ready for public use and creating applications in various fields including development of events reconstruction software for small and moderate scale HEP experiments.

  4. Hierarchy Software Development Framework (h-dp-fwk) project

    Energy Technology Data Exchange (ETDEWEB)

    Zaytsev, A, E-mail: Alexander.S.Zaytsev@gmail.co [Budker Institute of Nuclear Physics, Novosibirsk (Russian Federation)

    2010-04-01

    Hierarchy Software Development Framework provides a lightweight tool for building portable modular applications for performing automated data analysis tasks in a batch mode. The history of design and development activities devoted to the project has begun in March 2005 and from the very beginning it was targeting the case of building experimental data processing applications for the CMD-3 experiment which is being commissioned at Budker Institute of Nuclear Physics (BINP, Novosibirsk, Russia). Its design addresses the generic case of modular data processing application operating within the well defined distributed computing environment. The main features of the framework are modularity, built-in message and data exchange mechanisms, XInclude and XML schema enabled XML configuration management tools, dedicated log management tools, internal debugging tools, both dynamic and static module chains support, internal DSO version and consistency checking, well defined API for developing specialized frameworks. It is supported on Scientific Linux 4 and 5 and planned to be ported to other platforms as well. The project is provided with the comprehensive set of technical documentation and users' guides. The licensing schema for the source code, binaries and documentation implies that the product is free for non-commercial use. Although the development phase is not over and many features are to be implemented yet the project is considered ready for public use and creating applications in various fields including development of events reconstruction software for small and moderate scale HEP experiments.

  5. Software for project-based learning of robot motion planning

    Science.gov (United States)

    Moll, Mark; Bordeaux, Janice; Kavraki, Lydia E.

    2013-12-01

    Motion planning is a core problem in robotics concerned with finding feasible paths for a given robot. Motion planning algorithms perform a search in the high-dimensional continuous space of robot configurations and exemplify many of the core algorithmic concepts of search algorithms and associated data structures. Motion planning algorithms can be explained in a simplified two-dimensional setting, but this masks many of the subtleties and complexities of the underlying problem. We have developed software for project-based learning of motion planning that enables deep learning. The projects that we have developed allow advanced undergraduate students and graduate students to reflect on the performance of existing textbook algorithms and their own variations on such algorithms. Formative assessment has been conducted at three institutions. The core of the software used for this teaching module is also used within the Robot Operating System, a widely adopted platform by the robotics research community. This allows for transfer of knowledge and skills to robotics research projects involving a large variety robot hardware platforms.

  6. Incorporation of the KERN ECDS-PC software into a project oriented software environment

    International Nuclear Information System (INIS)

    Oren, W.; Pushor, R.; Ruland, R.

    1986-11-01

    The Stanford Linear Accelerator Center (SLAC) is in the process of building a new particle collider, the Stanford Linear Collider (SLC). The tunnel which houses the SLC is about 3 km long and contains approximately 1000 magnets. Besides a very precise absolute positioning of these magnets, the alignment of adjacent magnet ends is of particular importance to the success of the whole project. Because of this and the limited time frame, a survey method which was not only reliable and self-checking but also fast had to be developed. Therefore, the concept of MAS (Magnet Alignment System) was developed. This system utilizes the on-line data collection and the rigorous least-squares bundle adjustment of the KERN ECDS-PC system to fulfill these requirements. The ECDS software is embedded in a project tailored software system with modules which take care of: fixture and magnet calibration corrections, the calculation of ideal coordinates and their comparison to measured coordinates, the translation of detected misalignments into the coordinate system of the mechanical adjustments and the control of the adjustments with on-line electronic dial-gauges. This paper gives a brief introduction to the SLC project and some of the survey problems which are unique to this machine. The basic ideas of the KERN ECDS-PC system are explained and a discussion of the practical aspects, such as targeting and set-ups, are given. MAS and its modules are explained in detail

  7. The Impact of Organization, Project and Governance Variables on Software Quality and Project Success

    OpenAIRE

    Abbas, Noura; Gravell, Andy; Wills, Gary

    2010-01-01

    In this paper we present a statistically tested evidence about how quality and success rate are correlated with variables reflecting the organization and aspects of its project’s governance, namely retrospectives and metrics. The results presented in this paper are based on the Agile Projects Governance Survey that collected 129 responses. This paper discuss the deep analysis of this survey, and the main findings suggest that when applying agile software development, the quality of software i...

  8. SAGA: A project to automate the management of software production systems

    Science.gov (United States)

    Campbell, Roy H.; Laliberte, D.; Render, H.; Sum, R.; Smith, W.; Terwilliger, R.

    1987-01-01

    The Software Automation, Generation and Administration (SAGA) project is investigating the design and construction of practical software engineering environments for developing and maintaining aerospace systems and applications software. The research includes the practical organization of the software lifecycle, configuration management, software requirements specifications, executable specifications, design methodologies, programming, verification, validation and testing, version control, maintenance, the reuse of software, software libraries, documentation, and automated management.

  9. The Wireless ATM Architecture

    Directory of Open Access Journals (Sweden)

    R. Palitefka

    1998-06-01

    Full Text Available An overview of the proposed wireless ATM structure is provided. Wireless communication have been developed to a level where offered services can now be extended beyond voice and data. There are already wireless LANs, cordless systems offering data services and mobile data. Wireless LAN systems are basically planned for local, on-promises and in-house networking providing short distance radio or infrared links between computer system. The main challenge of wireless ATM is to harmonise the development of broadband wireless system with service B -ISDN/ATM and ATM LANs, and offer multimedia multiservice features for the support of time-sensitive voice communication, video, desktop multimedia applications, and LAN data traffic for the wireless user.

  10. Study on Top-Down Estimation Method of Software Project Planning

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jun-guang; L(U) Ting-jie; ZHAO Yu-mei

    2006-01-01

    This paper studies a new software project planning method under some actual project data in order to make software project plans more effective. From the perspective of system theory, our new method regards a software project plan as an associative unit for study. During a top-down estimation of a software project, Program Evaluation and Review Technique (PERT) method and analogy method are combined to estimate its size, then effort estimation and specific schedules are obtained according to distributions of the phase effort. This allows a set of practical and feasible planning methods to be constructed. Actual data indicate that this set of methods can lead to effective software project planning.

  11. Software for Distributed Computation on Medical Databases: A Demonstration Project

    Directory of Open Access Journals (Sweden)

    Balasubramanian Narasimhan

    2017-05-01

    Full Text Available Bringing together the information latent in distributed medical databases promises to personalize medical care by enabling reliable, stable modeling of outcomes with rich feature sets (including patient characteristics and treatments received. However, there are barriers to aggregation of medical data, due to lack of standardization of ontologies, privacy concerns, proprietary attitudes toward data, and a reluctance to give up control over end use. Aggregation of data is not always necessary for model fitting. In models based on maximizing a likelihood, the computations can be distributed, with aggregation limited to the intermediate results of calculations on local data, rather than raw data. Distributed fitting is also possible for singular value decomposition. There has been work on the technical aspects of shared computation for particular applications, but little has been published on the software needed to support the "social networking" aspect of shared computing, to reduce the barriers to collaboration. We describe a set of software tools that allow the rapid assembly of a collaborative computational project, based on the flexible and extensible R statistical software and other open source packages, that can work across a heterogeneous collection of database environments, with full transparency to allow local officials concerned with privacy protections to validate the safety of the method. We describe the principles, architecture, and successful test results for the site-stratified Cox model and rank-k singular value decomposition.

  12. Building Software, Building Community: Lessons from the Ropensci Project

    Science.gov (United States)

    Boettiger, C.

    2014-12-01

    rOpenSci is a developer collective originally formed in 2011 by graduate students and post-docs from ecology and evolutionary biology to collaborate on building software tools to facilitate a more open and synthetic approach in the face of transformative rise of large and heterogeneous data. Born on the internet (the collective only began through chance discussions over social media), we have grown into a widely recognized effort that supports an ecosystem of some 45software packages, engages scores of collaborators, has taught dozens of workshops around the world, and has secured over $480,000 in grant support. As young scientists working in an academic context largely without direct support for our efforts, we have first hand experience with most of the the technical and social challenges in developing sustainable scientific software. I will summarize our experiences, the challenges we have faced, and describe our approach and success in building an effective and diverse community around the rOpenSci project.

  13. Guidance and Control Software Project Data - Volume 4: Configuration Management and Quality Assurance Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes configuration management and quality assurance documents from the GCS project. Volume 4 contains six appendices: A. Software Accomplishment Summary for the Guidance and Control Software Project; B. Software Configuration Index for the Guidance and Control Software Project; C. Configuration Management Records for the Guidance and Control Software Project; D. Software Quality Assurance Records for the Guidance and Control Software Project; E. Problem Report for the Pluto Implementation of the Guidance and Control Software Project; and F. Support Documentation Change Reports for the Guidance and Control Software Project.

  14. Experiment Software and Projects on the Web with VISPA

    Science.gov (United States)

    Erdmann, M.; Fischer, B.; Fischer, R.; Geiser, E.; Glaser, C.; Müller, G.; Rieger, M.; Urban, M.; von Cube, R. F.; Welling, C.

    2017-10-01

    The Visual Physics Analysis (VISPA) project defines a toolbox for accessing software via the web. It is based on latest web technologies and provides a powerful extension mechanism that enables to interface a wide range of applications. Beyond basic applications such as a code editor, a file browser, or a terminal, it meets the demands of sophisticated experiment-specific use cases that focus on physics data analyses and typically require a high degree of interactivity. As an example, we developed a data inspector that is capable of browsing interactively through event content of several data formats, e.g., MiniAOD which is utilized by the CMS collaboration. The VISPA extension mechanism can also be used to embed external web-based applications that benefit from dynamic allocation of user-defined computing resources via SSH. For example, by wrapping the JSROOT project, ROOT files located on any remote machine can be inspected directly through a VISPA server instance. We introduced domains that combine groups of users and role-based permissions. Thereby, tailored projects are enabled, e.g. for teaching where access to student’s homework is restricted to a team of tutors, or for experiment-specific data that may only be accessible for members of the collaboration. We present the extension mechanism including corresponding applications and give an outlook onto the new permission system.

  15. CAVEAT: an assistance project for software validation using formal techniques

    International Nuclear Information System (INIS)

    Trotin, A.; Antoine, C.; Baudin, P.; Collart, J.M.; Raguideau, J.; Zylberajch, C.

    1995-01-01

    The aim of the CAVEAT project is to provide a tool for the validation of industrial C language softwares. It allows the user to go inside the program and have a good comprehension of it. It allows also the possibility to realize refined verifications of the consistency between the specifications and the program by translating the properties into a more suitable language. It calculates automatically the conditions to demonstrate, and offers an assistance to perform interactive demonstrations. The principal application of this tool is the safety of systems during the verification/certification phase or during the developing phase where it can works as an intelligent debugging system. (J.S.). 5 refs., 1 fig

  16. Vague project start makes project success of outsourced software development projects uncertain

    OpenAIRE

    Savolainen, Paula

    2010-01-01

    peer-reviewed A definition of a project success includes at least three criteria: 1) meeting planning goals, 2) customer benefits, and 3) supplier benefits. This study aims to point out the importance of the definition of the project start, the project start date, and what work should be included in the project effort in order to ensure the supplier's benefits. The ambiguity of the project start risks the profitability of the project and therefore makes project success at least from suppli...

  17. The Generalizability of Private Sector Research on Software Project Management in Two USAF Organizations: An Exploratory Study

    National Research Council Canada - National Science Library

    Garman, Michael

    2003-01-01

    ... budget. However, software projects frequently fail to meet these criteria. Software engineers, acquisition officers, and project managers have all studied this issue and made recommendations for achieving success...

  18. Coordination Implications of Software Coupling in Open Source Projects

    NARCIS (Netherlands)

    Amrit, Chintan Amrit; van Hillegersberg, Jos; Ågerfalk, Pär

    2010-01-01

    The effect of software coupling on the quality of software has been studied quite widely since the seminal paper on software modularity by Parnas [1]. However, the effect of the increase in software coupling on the coordination of the developers has not been researched as much. In commercial

  19. Using UML Modeling to Facilitate Three-Tier Architecture Projects in Software Engineering Courses

    Science.gov (United States)

    Mitra, Sandeep

    2014-01-01

    This article presents the use of a model-centric approach to facilitate software development projects conforming to the three-tier architecture in undergraduate software engineering courses. Many instructors intend that such projects create software applications for use by real-world customers. While it is important that the first version of these…

  20. Health ATMs in Saudi Arabia: A Perspective.

    Science.gov (United States)

    Aldosari, Bakheet

    2017-06-01

    Health ATMs are terminals which are connected to a centrally located database storing patients' electronic healthcare records (EHR). These machines are capable of collecting information in a far superior fashion than humans and are also able to rectify obsolete data in a manner that humans are generally not inclined to. The main goal of this study is to assess the importance of adopting health ATMs in the Kingdom of Saudi Arabia (KSA), which can improve the confidence of patients, reward health self-management, and achieve positive health outcomes through their easy-to-use applications that are secure and accessible through various devices. Strength, Weakness, Opportunity, and Threat (SWOT) analysis was used to assess the efficiency of adopting health ATMs in KSA and reveal the said characteristics. Three focus groups assembled in the cities of Riyadh, Jeddah and Dammam during the period 2013-2014. The groups consisted of individuals experienced in the function of health ATMs. It was found that the sector possessed a number of strengths that would help it in reaching the goals outlined therein, thereby achieving successful outcomes. Health ATMs could be a promising new advancement in the field of health if the project were to be planned and implemented correctly. Their benefits would consequently reach organizational and national levels. It is, therefore, crucial to educate the project managers about the benefits of learning from others as well as educating them about the needs and the requirements of the concerned organization.

  1. Grounded Theory Study of Conflicts in Norwegian Agile Software Projects: The Project Managers’ Perspective

    Directory of Open Access Journals (Sweden)

    Lubna Siddique

    2016-07-01

    Full Text Available This paper aims to explore the process of conflicts in agile software projects. The purpose was to investigate the causes and consequences of these conflicts. For this purpose, we conducted a qualitative study involving agile software projects in Norway. Grounded theory was used to analyze the data and the interview findings are presented using Glaser´s Six C model (context, condition, causes, consequences, contingencies, and covariance. The research findings suggest that there are several causes of conflicts. These include: the role of the product owner, an inexperienced project manager, the customer’s lack of knowledge about methodology organizational hierarchy in public companies, contracting, personal egos, financial issues, not getting the right team. Consequences of conflicts include: decreased productivity, wastage of time and resources, diverted attention from project objectives loss of motivation, poor decision making, loss of communication. Based on interview data, different conflict strategies are suggested and these include appropriately skilled project manager, communication and negotiation, defining clear roles, stakeholder analysis, managing stakeholder´s expectations, discussion, finding the root cause of conflict. Project managers are using these strategies to avoid or resolve conflicts. The competencies required to handle these kind of conflicts are also discussed in the paper, while the implications of theory and practice of conflict management theory are also presented.

  2. ATMS Step By Step.

    Science.gov (United States)

    National Library of Australia, Canberra.

    This manual is designed to provide an introduction and basic guide to the use of IBM's Advanced Text Management System (ATMS), the text processing system to be used for the creation of Australian data bases within AUSINET. Instructions are provided for using the system to enter, store, retrieve, and modify data, which may then be displayed at the…

  3. Advanced software development workstation project: Engineering scripting language. Graphical editor

    Science.gov (United States)

    1992-01-01

    Software development is widely considered to be a bottleneck in the development of complex systems, both in terms of development and in terms of maintenance of deployed systems. Cost of software development and maintenance can also be very high. One approach to reducing costs and relieving this bottleneck is increasing the reuse of software designs and software components. A method for achieving such reuse is a software parts composition system. Such a system consists of a language for modeling software parts and their interfaces, a catalog of existing parts, an editor for combining parts, and a code generator that takes a specification and generates code for that application in the target language. The Advanced Software Development Workstation is intended to be an expert system shell designed to provide the capabilities of a software part composition system.

  4. Software development infrastructure for the HYBRID modeling and simulation project

    International Nuclear Information System (INIS)

    Epiney, Aaron S.; Kinoshita, Robert A.; Kim, Jong Suk; Rabiti, Cristian; Greenwood, M. Scott

    2016-01-01

    One of the goals of the HYBRID modeling and simulation project is to assess the economic viability of hybrid systems in a market that contains renewable energy sources like wind. The idea is that it is possible for the nuclear plant to sell non-electric energy cushions, which absorb (at least partially) the volatility introduced by the renewable energy sources. This system is currently modeled in the Modelica programming language. To assess the economics of the system, an optimization procedure is trying to find the minimal cost of electricity production. The RAVEN code is used as a driver for the whole problem. It is assumed that at this stage, the HYBRID modeling and simulation framework can be classified as non-safety “research and development” software. The associated quality level is Quality Level 3 software. This imposes low requirements on quality control, testing and documentation. The quality level could change as the application development continues.Despite the low quality requirement level, a workflow for the HYBRID developers has been defined that include a coding standard and some documentation and testing requirements. The repository performs automated unit testing of contributed models. The automated testing is achieved via an open-source python script called BuildingsP from Lawrence Berkeley National Lab. BuildingsPy runs Modelica simulation tests using Dymola in an automated manner and generates and runs unit tests from Modelica scripts written by developers. In order to assure effective communication between the different national laboratories a biweekly videoconference has been set-up, where developers can report their progress and issues. In addition, periodic face-face meetings are organized intended to discuss high-level strategy decisions with management. A second means of communication is the developer email list. This is a list to which everybody can send emails that will be received by the collective of the developers and managers

  5. Software development infrastructure for the HYBRID modeling and simulation project

    Energy Technology Data Exchange (ETDEWEB)

    Epiney, Aaron S. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert A. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kim, Jong Suk [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Greenwood, M. Scott [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    One of the goals of the HYBRID modeling and simulation project is to assess the economic viability of hybrid systems in a market that contains renewable energy sources like wind. The idea is that it is possible for the nuclear plant to sell non-electric energy cushions, which absorb (at least partially) the volatility introduced by the renewable energy sources. This system is currently modeled in the Modelica programming language. To assess the economics of the system, an optimization procedure is trying to find the minimal cost of electricity production. The RAVEN code is used as a driver for the whole problem. It is assumed that at this stage, the HYBRID modeling and simulation framework can be classified as non-safety “research and development” software. The associated quality level is Quality Level 3 software. This imposes low requirements on quality control, testing and documentation. The quality level could change as the application development continues.Despite the low quality requirement level, a workflow for the HYBRID developers has been defined that include a coding standard and some documentation and testing requirements. The repository performs automated unit testing of contributed models. The automated testing is achieved via an open-source python script called BuildingsP from Lawrence Berkeley National Lab. BuildingsPy runs Modelica simulation tests using Dymola in an automated manner and generates and runs unit tests from Modelica scripts written by developers. In order to assure effective communication between the different national laboratories a biweekly videoconference has been set-up, where developers can report their progress and issues. In addition, periodic face-face meetings are organized intended to discuss high-level strategy decisions with management. A second means of communication is the developer email list. This is a list to which everybody can send emails that will be received by the collective of the developers and managers

  6. Quality Assurance in Software Development: An Exploratory Investigation in Software Project Failures and Business Performance

    Science.gov (United States)

    Ichu, Emmanuel A.

    2010-01-01

    Software quality is perhaps one of the most sought-after attributes in product development, however; this goal is unattained. Problem factors in software development and how these have affected the maintainability of the delivered software systems requires a thorough investigation. It was, therefore, very important to understand software…

  7. Lessons learned from development and quality assurance of software systems at the Halden Project

    International Nuclear Information System (INIS)

    Bjorlo, T.J.; Berg, O.; Pehrsen, M.; Dahll, G.; Sivertsen, T.

    1996-01-01

    The OECD Halden Reactor Project has developed a number of software systems within the research programmes. These programmes have comprised a wide range of topics, like studies of software for safety-critical applications, development of different operator support systems, and software systems for building and implementing graphical user interfaces. The systems have ranged from simple prototypes to installations in process plants. In the development of these software systems, Halden has gained much experience in quality assurance of different types of software. This paper summarises the accumulated experience at the Halden Project in quality assurance of software systems. The different software systems being developed at the Halden Project may be grouped into three categories. These are plant-specific software systems (one-of-a-kind deliveries), generic software products, and safety-critical software systems. This classification has been found convenient as the categories have different requirements to the quality assurance process. In addition, the experience from use of software development tools and proprietary software systems at Halden, is addressed. The paper also focuses on the experience gained from the complete software life cycle, starting with the software planning phase and ending with software operation and maintenance

  8. Web Based ATM PVC Management

    NARCIS (Netherlands)

    van der Waaij, B.D.; Sprenkels, Ron; van Beijnum, Bernhard J.F.; Pras, Aiko

    1998-01-01

    This paper discusses the design of a public domain web based ATM PVC Management tool for the Dutch SURFnet research ATM network. The aim of this tool is to assists in the creation and deletion of PVCs through local and remote ATM network domains. The tool includes security mechanisms to restrict the

  9. Future ATM Concepts Evaluation Tool (FACET) Interface Control Document

    Science.gov (United States)

    Grabbe, Shon R.

    2017-01-01

    This Interface Control Document (ICD) documents the airspace adaptation and air traffic inputs of NASA's Future ATM Concepts and Evaluation Tool (FACET). Its intended audience is the project manager, project team, development team, and stakeholders interested in interfacing with the system. FACET equips Air Traffic Management (ATM) researchers and service providers with a way to explore, develop and evaluate advanced air transportation concepts before they are field-tested and eventually deployed. FACET is a flexible software tool that is capable of quickly generating and analyzing thousands of aircraft trajectories. It provides researchers with a simulation environment for preliminary testing of advanced ATM concepts. Using aircraft performance profiles, airspace models, weather data, and flight schedules, the tool models trajectories for the climb, cruise, and descent phases of flight for each type of aircraft. An advanced graphical interface displays traffic patterns in two and three dimensions, under various current and projected conditions for specific airspace regions or over the entire continental United States. The system is able to simulate a full day's dynamic national airspace system (NAS) operations, model system uncertainty, measure the impact of different decision-makers in the NAS, and provide analysis of the results in graphical form, including sector, airport, fix, and airway usage statistics. NASA researchers test and analyze the system-wide impact of new traffic flow management algorithms under anticipated air traffic growth projections on the nation's air traffic system. In addition to modeling the airspace system for NASA research, FACET has also successfully transitioned into a valuable tool for operational use. Federal Aviation Administration (FAA) traffic flow managers and commercial airline dispatchers have used FACET technology for real-time operations planning. FACET integrates live air traffic data from FAA radar systems and weather data

  10. Software Assurance Curriculum Project Volume 1: Master of Software Assurance Reference Curriculum

    Science.gov (United States)

    2010-08-01

    developed products. The above definition was derived from these references: [IEEE-CS 2008] ISO /IEC 12207 , IEEE Std 12207 -2008, Systems and Software...Systems [CNSS 2009]. Software quality Capability of a software product to satisfy stated and implied needs when used under specified conditions [ ISO ...Curriculum ISO International Organization for Standardization IT information technology KA knowledge area KU knowledge unit MBA Master of

  11. Automated Transportation Management System (ATMS) user's manual. Revision 1

    International Nuclear Information System (INIS)

    Smith, P.D.

    1994-01-01

    The Automated Transportation Management System (ATMS) Software User Guide (SUG) constitutes the user procedures for the ATMS System. Information in this document will be used by the user to operate the automated system. It is intended to be used as a reference manual to guide and direct the user(s) through the ATMS software product and its environment. The objectives of ATMS are as follows: to better support the Procurement function with freight rate information; to free Transportation Logistics personnel from routine activities such as the auditing and input of freight billing information; to comply with Headquarters Department of Energy-Inspector General (DOE-IG) audit findings to automate transportation management functions; to reduce the keying of data into the Shipment Mobility Accountability Collection (SMAC) database; and to provide automation for the preparing of Bill of Lading, Declaration of Dangerous Goods, Emergency Response Guide and shipping Labels using HM181 Retrieval of hazardous material table text information

  12. Software project profitability analysis using temporal probabilistic reasoning; an empirical study with the CASSE framework

    CSIR Research Space (South Africa)

    Balikuddembe, JK

    2009-04-01

    Full Text Available Undertaking adequate risk management by understanding project requirements and ensuring that viable estimates are made on software projects require extensive application and sophisticated techniques of analysis and interpretation. Informative...

  13. Delivering Software Process-Specific Project Courses in Tertiary Education Environment: Challenges and Solution

    Science.gov (United States)

    Rong, Guoping; Shao, Dong

    2012-01-01

    The importance of delivering software process courses to software engineering students has been more and more recognized in China in recent years. However, students usually cannot fully appreciate the value of software process courses by only learning methodology and principle in the classroom. Therefore, a process-specific project course was…

  14. Software development project success and failure from the supplier's perspective: A systematic literature review

    OpenAIRE

    Savolainen, Paula; Ahonen, Jarmo J.; Richardson, Ita

    2012-01-01

    peer-reviewed In this paper, we consider software development project success and failure from the supplier's perspective. First we clarified concepts in order to be able to exclude review articles on in-house projects, continuous services, the customer's perspective, and software product development, with the aim of providing valid results for supplier firms. We divided success criteria into project success and project management (PM) success, and, in seven articles, identified thre...

  15. Teleoperation system using Asynchronous transfer mode, ATM network

    International Nuclear Information System (INIS)

    Mohd Dani Baba; A Nasoruddin Mohamad

    1999-01-01

    This paper examines the application of Asynchronous Transfer Mode (ATM) in a distributed industrial environment such as in teleoperation, which performs real time control manipulation from a remote location. In our study, two models of teleoperation are proposed; the first model is a point to point connection and the second model is through an ATM network. The performance results are analysed as to determine whether the two models can support the teleoperation traffics via simulation using commercial software design tool. (Author)

  16. SEffEst: Effort estimation in software projects using fuzzy logic and neural networks

    Directory of Open Access Journals (Sweden)

    Israel

    2012-08-01

    Full Text Available Academia and practitioners confirm that software project effort prediction is crucial for an accurate software project management. However, software development effort estimation is uncertain by nature. Literature has developed methods to improve estimation correctness, using artificial intelligence techniques in many cases. Following this path, this paper presents SEffEst, a framework based on fuzzy logic and neural networks designed to increase effort estimation accuracy on software development projects. Trained using ISBSG data, SEffEst presents remarkable results in terms of prediction accuracy.

  17. Software-Enabled Project Management Techniques and Their Relationship to the Triple Constraints

    Science.gov (United States)

    Elleh, Festus U.

    2013-01-01

    This study investigated the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). There was the dearth of academic literature that focused on the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). Based on the gap…

  18. An Agile Constructionist Mentoring Methodology for Software Projects in the High School

    Science.gov (United States)

    Meerbaum-Salant, Orni; Hazzan, Orit

    2010-01-01

    This article describes the construction process and evaluation of the Agile Constructionist Mentoring Methodology (ACMM), a mentoring method for guiding software development projects in the high school. The need for such a methodology has arisen due to the complexity of mentoring software project development in the high school. We introduce the…

  19. Extensive Evaluation of Using a Game Project in a Software Architecture Course

    Science.gov (United States)

    Wang, Alf Inge

    2011-01-01

    This article describes an extensive evaluation of introducing a game project to a software architecture course. In this project, university students have to construct and design a type of software architecture, evaluate the architecture, implement an application based on the architecture, and test this implementation. In previous years, the domain…

  20. The Software Life-Cycle Based Configuration Management Tasks for the KNICS Project

    International Nuclear Information System (INIS)

    Cheon, Se Woo; Kwon, Kee Choon

    2005-01-01

    Software configuration management (SCM) is an activity, which configures the form of a software system (e.g., design documents and programs) and systematically manages and controls the modifications used to compile the plans, development, and operations resulting from software development and maintenance. The SCM tool, NuSCM, has been specifically developed for the software life-cycle configuration management of developing the KNICS plant protection system (PPS). This paper presents the application of NuSCM to the KNICS project

  1. IT & C Projects Duration Assessment Based on Audit and Software Reengineering

    Directory of Open Access Journals (Sweden)

    2009-01-01

    Full Text Available This paper analyses the effect of applying the core elements of software engineering and reengineering, probabilistic simulations and system development auditing to software development projects. Our main focus is reducing software development project duration. Due to the fast changing economy, the need for efficiency and productivity is greater than ever. Optimal allocation of resources has proved to be the main element contributing to an increase in efficiency.

  2. Virtual C Machine and Integrated Development Environment for ATMS Controllers.

    Science.gov (United States)

    2000-04-01

    The overall objective of this project is to develop a prototype virtual machine that fits on current Advanced Traffic Management Systems (ATMS) controllers and provides functionality for complex traffic operations.;Prepared in cooperation with Utah S...

  3. Barriers to Learning in Agile Software Development Projects

    DEFF Research Database (Denmark)

    Babb, Jeffry S.; Hoda, Rashina; Nørbjerg, Jacob

    2013-01-01

    The adoption of agile methods promises many advantages for individual, team, and organizational learning. However, environmental, structural, and organizational/cultural constraints often find teams adapting agile software development methods rather than engaging in full adoption. We present resu...

  4. Description of a project management system software tool (Sugar)

    International Nuclear Information System (INIS)

    Saito, T.

    2000-01-01

    Toshiba has developed a project management tool that can be applied to large-scale and complicated projects such as the outage of a nuclear power station. The project management tool (Sugar) which Toshiba developed is excellent in operative visibility and extendibility, and has been developed from the beginning for use in nuclear periodic-inspection project control. Here, the development circumstances of this project management tool (Sugar) and the feature are described, and an easy demonstration is provided as an example. (author)

  5. The use of intelligent systems for risk management in software projects

    Directory of Open Access Journals (Sweden)

    Oksana A. Gushchina

    2017-06-01

    Full Text Available Introduction: The article identifies the main risks of a software project, examines the use of different types of intelligent systems in the risk management process for software projects, discusses the basic methods used for process estimation and forecasting in the field of software engineering, identifies currently used empty expert systems, software systems for analysis and risk management of software projects. Materials and Methods: The author describes the peculiarities of risk management in the field of software engineering with involvement of intelligent systems. The intelligent techniques allow solving the control task with expert precision without the involvement of human experts. Results: The result of this work: – identification of the key risks of a software project (tax, legal, financial and commercial risks, IT risks, personnel risks, risks related to competitors, suppliers, marketing and demand and market; – investigation of the current, applied to risk management of software system projects, artificial intelligence, particularly expert systems and software tools for evaluation of the process results; – identification of the most popular empty expert systems (Clips, G2 and Leonardo and software products of the analysis of large databases (Orange, Weka, Rattle GUI, Apache Mahout, SCaViS, RapidMiner, Databionic ESOM Tools, ELKI, KNIME, Pandas and UIMA; – consideration of the cluster, correlation, regression, factor and dispersion analysis methods for the estimation and prediction of the processes of software engineering. Discussion and Conclusions: The results show the feasibility of the application of various intelligent systems in the risk management process. The analysis of methods of evaluating risks and the tendency of their application in the modern systems of intellectual analysis can serve as a start point for creating a unified system of risk management for software projects of medium and high complexity with a

  6. Software Support for the Classical, Contemporary and Future Project Management

    OpenAIRE

    Jakov Crnkovic; Peter Ross; Sanjay Desai

    2006-01-01

    The volume and complexity of Project Management (PM) raises many questions for managers. What exactly are we managing? People? Performance? Efficiency? Effectiveness? Cost? Time? At what levels do projects become challenging and worthy of significant management attention? Can some projects be left on auto-pilot? Must others be managed more aggressively? What metrics are useful in Project Management? How can they be integrated with normal performance metrics in the organization? How can metric...

  7. Results of the EC research project REQUEST on software quality and reliability

    International Nuclear Information System (INIS)

    Kersken, M.; Saglietti, F.

    1990-01-01

    GRS work in software safety was mainly concerned with the qualitative assessment of software reliability and quality. As a supplement to these activities the work within the REQUEST project emphasized the quantitative determination of the respective parameters. The three-level quality model COQUAMO serves for the computation - and partly for the prediction - of quality factors during the software life cycle. PERFIDE controls the application of software reliability models during the test phase and in early operational life. Specific attention was paid to the assessment of fault-tolerant diverse software systems. (orig.) [de

  8. Management of Globally Distributed Component-Based Software Development Projects

    NARCIS (Netherlands)

    J. Kotlarsky (Julia)

    2005-01-01

    textabstractGlobally Distributed Component-Based Development (GD CBD) is expected to become a promising area, as increasing numbers of companies are setting up software development in a globally distributed environment and at the same time are adopting CBD methodologies. Being an emerging area, the

  9. Mars Science Laboratory Flight Software Boot Robustness Testing Project Report

    Science.gov (United States)

    Roth, Brian

    2011-01-01

    On the surface of Mars, the Mars Science Laboratory will boot up its flight computers every morning, having charged the batteries through the night. This boot process is complicated, critical, and affected by numerous hardware states that can be difficult to test. The hardware test beds do not facilitate testing a long duration of back-to-back unmanned automated tests, and although the software simulation has provided the necessary functionality and fidelity for this boot testing, there has not been support for the full flexibility necessary for this task. Therefore to perform this testing a framework has been build around the software simulation that supports running automated tests loading a variety of starting configurations for software and hardware states. This implementation has been tested against the nominal cases to validate the methodology, and support for configuring off-nominal cases is ongoing. The implication of this testing is that the introduction of input configurations that have yet proved difficult to test may reveal boot scenarios worth higher fidelity investigation, and in other cases increase confidence in the robustness of the flight software boot process.

  10. Developer’s time spent in a software project part using the SGD framework

    OpenAIRE

    Ciesluk, Simon

    2016-01-01

    Resource management is important for software projects to be successful. Time is one of these resources that needs to be managed. To do this you need to know how time resources are spent. Currently the existence of published material on time resources spent in a software project is almost none. In this thesis a research was conducted on how time resources are spent by an individual developer in a software project. The Self-Governance Developer framework was the tool used to gather these resou...

  11. Resource Planning and Management: Job One for Software Project Managers

    Science.gov (United States)

    2011-05-01

    negotiation based on mutual understanding of and belief i th j t t t i lAcceptancen e pro ec managemen r ang e – Project leaders need to communicate...Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that...puts the figure at $1.22 T (even more zeros) Constant barrage of project doom and gloom Optimize tomorrow today.TM …. Reasons for Project

  12. Success Rates by Software Development Methodology in Information Technology Project Management: A Quantitative Analysis

    Science.gov (United States)

    Wright, Gerald P.

    2013-01-01

    Despite over half a century of Project Management research, project success rates are still too low. Organizations spend a tremendous amount of valuable resources on Information Technology projects and seek to maximize the utility gained from their efforts. The author investigated the impact of software development methodology choice on ten…

  13. Factors that Impact Software Project Success in Offshore Information Technology (IT) Companies

    Science.gov (United States)

    Edara, Venkatarao

    2011-01-01

    Information technology (IT) projects are unsuccessful at a rate of 65% to 75% per year, in spite of employing the latest technologies and training employees. Although many studies have been conducted on project successes in U.S. companies, there is a lack of research studying the impact of various factors on software project success in offshore IT…

  14. The dynamics of software development project management: An integrative systems dynamic perspective

    Science.gov (United States)

    Vandervelde, W. E.; Abdel-Hamid, T.

    1984-01-01

    Rather than continuing to focus on software development projects per se, the system dynamics modeling approach outlined is extended to investigate a broader set of issues pertaining to the software development organization. Rather than trace the life cycle(s) of one or more software projects, the focus is on the operations of a software development department as a continuous stream of software products are developed, placed into operation, and maintained. A number of research questions are ""ripe'' for investigating including: (1) the efficacy of different organizational structures in different software development environments, (2) personnel turnover, (3) impact of management approaches such as management by objectives, and (4) the organizational/environmental determinants of productivity.

  15. Satellite Communications for ATM

    Science.gov (United States)

    Shamma, Mohammed A.

    2003-01-01

    This presentation is an overview on Satellite Communication for the Aeronautical Telecommunication Management (ATM) research. Satellite Communications are being considered by the FAA and NASA as a possible alternative to the present and future ground systems supporting Air Traffic Communications. The international Civil Aviation Organization (ICAO) have in place Standards and Recommended Practices (SARPS) for the Aeronautical Mobile Satellite Services (AMSS) which is mainly derived from the pre-existing Inmarsat service that has been in service since the 1980s. The Working Group A of the Aeronautical Mobile Communication Panel of ICAO has also been investigating SARPS for what is called the Next Generation Satellite Service (NGSS) which conforms less to the Inmarsat based architecture and explores wider options in terms of satellite architectures. Several designs are being proposed by Firms such as Boeing, ESA, NASA that are geared toward full or secondary usage of satellite communications for ATM. Satellite communications for ATM can serve several purposes ranging from primary usage where ground services would play a minimal backup role, to an integrated solution where it will be used to cover services, or areas that are less likely to be supported by the proposed and existing ground infrastructure. Such Integrated roles can include usage of satellite communications for oceanic and remote land areas for example. It also can include relieving the capacity of the ground network by providing broadcast based services of Traffic Information Services messages (TIS-B), or Flight Information Services (FIS-B) which can take a significant portion of the ground system capacity. Additionally, satellite communication can play a backup role to support any needs for ground replacement, or additional needed capacity even after the new digital systems are in place. The additional bandwidth that can be provided via satellite communications can also open the door for many new

  16. Software Project Management and Measurement on the World-Wide-Web (WWW)

    Science.gov (United States)

    Callahan, John; Ramakrishnan, Sudhaka

    1996-01-01

    We briefly describe a system for forms-based, work-flow management that helps members of a software development team overcome geographical barriers to collaboration. Our system, called the Web Integrated Software Environment (WISE), is implemented as a World-Wide-Web service that allows for management and measurement of software development projects based on dynamic analysis of change activity in the workflow. WISE tracks issues in a software development process, provides informal communication between the users with different roles, supports to-do lists, and helps in software process improvement. WISE minimizes the time devoted to metrics collection and analysis by providing implicit delivery of messages between users based on the content of project documents. The use of a database in WISE is hidden from the users who view WISE as maintaining a personal 'to-do list' of tasks related to the many projects on which they may play different roles.

  17. Clinical software development for the Web: lessons learned from the BOADICEA project.

    Science.gov (United States)

    Cunningham, Alex P; Antoniou, Antonis C; Easton, Douglas F

    2012-04-10

    In the past 20 years, society has witnessed the following landmark scientific advances: (i) the sequencing of the human genome, (ii) the distribution of software by the open source movement, and (iii) the invention of the World Wide Web. Together, these advances have provided a new impetus for clinical software development: developers now translate the products of human genomic research into clinical software tools; they use open-source programs to build them; and they use the Web to deliver them. Whilst this open-source component-based approach has undoubtedly made clinical software development easier, clinical software projects are still hampered by problems that traditionally accompany the software process. This study describes the development of the BOADICEA Web Application, a computer program used by clinical geneticists to assess risks to patients with a family history of breast and ovarian cancer. The key challenge of the BOADICEA Web Application project was to deliver a program that was safe, secure and easy for healthcare professionals to use. We focus on the software process, problems faced, and lessons learned. Our key objectives are: (i) to highlight key clinical software development issues; (ii) to demonstrate how software engineering tools and techniques can facilitate clinical software development for the benefit of individuals who lack software engineering expertise; and (iii) to provide a clinical software development case report that can be used as a basis for discussion at the start of future projects. We developed the BOADICEA Web Application using an evolutionary software process. Our approach to Web implementation was conservative and we used conventional software engineering tools and techniques. The principal software development activities were: requirements, design, implementation, testing, documentation and maintenance. The BOADICEA Web Application has now been widely adopted by clinical geneticists and researchers. BOADICEA Web

  18. Software Assurance Curriculum Project Volume 3: Master of Software Assurance Course Syllabi

    Science.gov (United States)

    2011-07-01

    thods and process of model-driven development. • Pressman , Roger S., Software Engineering: A Practitioner’s Approach, 6th ed. McGraw Hill, 2009...audience • [Bishop 2002] Chapter 18 • [Allen 2008] Chapters 1, 2 • [ Pressman 2009] Chapter 1 • [Merkow 2010] Chapter 3 • [Mouratidis 2007...Allen 2008] Chapters 3,4 • [ Pressman 2009] Chapters 3,4 • [Merkow 2010] Chapter 5 • [DHS 2008-2009a] • [Mellado 2010] • [CERT 2009] 3

  19. Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS).

    Science.gov (United States)

    Enari, Masato; Matsushima-Hibiya, Yuko; Miyazaki, Makoto; Otomo, Ryo

    2017-01-01

    Ataxia-telangiectasia mutated (ATM) protein is a member of the phosphatidylinositol 3-phosphate kinase (PI3-K)-related protein kinase (PIKK) family and is implicated in the initiation of signaling pathways following DNA double strand breaks (DSBs) elicited by exposure to ionizing irradiation (IR) or radiomimetic compounds. Loss of function of the ATM gene product results in the human genetic disorder ataxia-telangiectasia (A-T) characterized by neurodegeneration, immunodeficiency, genomic instability, and cancer predisposition. In response to DSBs, ATM is activated and phosphorylates Ser/Thr-Gln (S/T-Q) sequences on numerous proteins participating in DNA-damage responses. Among these proteins, phosphorylation of the tumor suppressor p53 at Ser15 is known as a target for ATM, which leads to the dissociation of MDM2, an E3 ubiquitin ligase, from p53 to prevent MDM2-dependent p53 degradation. Ser46 on p53 is phosphorylated in response to DSBs and contributes to the preferential transactivation of pro-apoptotic genes, such as p53AIP1, Noxa, and PUMA, to prevent tumor formation. Our group have shown that not only ATM preferentially phosphorylates S/T-Q sequences, but also Ser46, which is a noncanonical site with an S-P sequence for ATM. Ser46 on p53 is directly phosphorylated by ATM in a p53 conformation-dependent manner using the ATP analogue-accepting ATM mutant (ATM-AS) system. This protocol summarizes an approach to identify direct numerous targets for ATM kinase and is used to elucidate ATM signaling pathways in the DNA damage responses.

  20. Analysis of Return on Investment in Different Types of Agile Software Development Project Teams

    Directory of Open Access Journals (Sweden)

    Goran MILANOV

    2012-01-01

    Full Text Available This exploratory study of IT project teams in Serbia investigates how the choice of agile methods in different development project teams affects the return-on-investment (ROI. In this paper different types of software project teams are analyzed in order to examine and identify the business-value of using agile methods. In various software development project teams, the ROI of agile methods is yet to be fully explored, while the ROI of traditional methods is well-understood. Since ROI is important indicator of the projects success, in this paper we examine the factors that influence the ROI both from software solution customer point of view, and different agile project teams.

  1. Software

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, R.; Budd, G.; Ross, E.; Wells, P.

    2010-07-15

    The software section of this journal presented new software programs that have been developed to help in the exploration and development of hydrocarbon resources. Software provider IHS Inc. has made additions to its geological and engineering analysis software tool, IHS PETRA, a product used by geoscientists and engineers to visualize, analyze and manage well production, well log, drilling, reservoir, seismic and other related information. IHS PETRA also includes a directional well module and a decline curve analysis module to improve analysis capabilities in unconventional reservoirs. Petris Technology Inc. has developed a software to help manage the large volumes of data. PetrisWinds Enterprise (PWE) helps users find and manage wellbore data, including conventional wireline and MWD core data; analysis core photos and images; waveforms and NMR; and external files documentation. Ottawa-based Ambercore Software Inc. has been collaborating with Nexen on the Petroleum iQ software for steam assisted gravity drainage (SAGD) producers. Petroleum iQ integrates geology and geophysics data with engineering data in 3D and 4D. Calgary-based Envirosoft Corporation has developed a software that reduces the costly and time-consuming effort required to comply with Directive 39 of the Alberta Energy Resources Conservation Board. The product includes an emissions modelling software. Houston-based Seismic Micro-Technology (SMT) has developed the Kingdom software that features the latest in seismic interpretation. Holland-based Joa Oil and Gas and Calgary-based Computer Modelling Group have both supplied the petroleum industry with advanced reservoir simulation software that enables reservoir interpretation. The 2010 software survey included a guide to new software applications designed to facilitate petroleum exploration, drilling and production activities. Oil and gas producers can use the products for a range of functions, including reservoir characterization and accounting. In

  2. Software Engineering and eLearning: The MuSofT Project - www.musoft.org

    Directory of Open Access Journals (Sweden)

    Ernst-Erich Doberkat

    2005-12-01

    Full Text Available eLearning supports the education in certain disciplines. Here, we report about novel eLearning concepts, techniques, and tools to support education in Software Engineering, a subdiscipline of computer science. We call this "Software Engineering eLearning". On the other side, software support is a substantial prerequisite for eLearning in any discipline. Thus, Software Engineering techniques have to be applied to develop and maintain those software systems. We call this "eLearning Software Engineering". Both aspects have been investigated in a large joint, BMBF-funded research project, termed MuSofT (Multimedia in Software Engineering. The main results are summarized in this paper.

  3. Project W-211, initial tank retrieval systems, retrieval control system software configuration management plan

    International Nuclear Information System (INIS)

    RIECK, C.A.

    1999-01-01

    This Software Configuration Management Plan (SCMP) provides the instructions for change control of the W-211 Project, Retrieval Control System (RCS) software after initial approval/release but prior to the transfer of custody to the waste tank operations contractor. This plan applies to the W-211 system software developed by the project, consisting of the computer human-machine interface (HMI) and programmable logic controller (PLC) software source and executable code, for production use by the waste tank operations contractor. The plan encompasses that portion of the W-211 RCS software represented on project-specific AUTOCAD drawings that are released as part of the C1 definitive design package (these drawings are identified on the drawing list associated with each C-1 package), and the associated software code. Implementation of the plan is required for formal acceptance testing and production release. The software configuration management plan does not apply to reports and data generated by the software except where specifically identified. Control of information produced by the software once it has been transferred for operation is the responsibility of the receiving organization

  4. WISE: Automated support for software project management and measurement. M.S. Thesis

    Science.gov (United States)

    Ramakrishnan, Sudhakar

    1995-01-01

    One important aspect of software development and IV&V is measurement. Unless a software development effort is measured in some way, it is difficult to judge the effectiveness of current efforts and predict future performances. Collection of metrics and adherence to a process are difficult tasks in a software project. Change activity is a powerful indicator of project status. Automated systems that can handle change requests, issues, and other process documents provide an excellent platform for tracking the status of the project. A World Wide Web based architecture is developed for (a) making metrics collection an implicit part of the software process, (b) providing metric analysis dynamically, (c) supporting automated tools that can complement current practices of in-process improvement, and (d) overcoming geographical barrier. An operational system (WISE) instantiates this architecture allowing for the improvement of software process in a realistic environment. The tool tracks issues in software development process, provides informal communication between the users with different roles, supports to-do lists (TDL), and helps in software process improvement. WISE minimizes the time devoted to metrics collection, analysis, and captures software change data. Automated tools like WISE focus on understanding and managing the software process. The goal is improvement through measurement.

  5. Accelerating Project and Process Improvement using Advanced Software Simulation Technology: From the Office to the Enterprise

    Science.gov (United States)

    2010-04-29

    Technology: From the Office Larry Smith Software Technology Support Center to the Enterprise 517 SMXS/MXDEA 6022 Fir Avenue Hill AFB, UT 84056 801...2010 to 00-00-2010 4. TITLE AND SUBTITLE Accelerating Project and Process Improvement using Advanced Software Simulation Technology: From the Office to

  6. Enhancing Software Engineering Education through Open Source Projects: Four Years of Students' Perspectives

    NARCIS (Netherlands)

    Papadopoulos, P.M.; Stamelos, I.G.; Meiszner, A.

    2015-01-01

    This paper presents the results after four years of running of an instructional method that utilizes free/libre open source software (FLOSS) projects as tools for teaching software engineering in formal education. In the last four academic years, a total of 408 juniors majoring in Informatics (in a

  7. Z-Plant material information tracking system (ZMITS) software development and integration project management plan

    International Nuclear Information System (INIS)

    IBSEN, T.G.

    1999-01-01

    This document plans for software and interface development governing the implementation of ZMITS and other supporting systems necessary to manage information for material stabilization needs of the Project Hanford Management Contract (PHMC)

  8. PLANNING QUALITY ASSURANCE PROCESSES IN A LARGE SCALE GEOGRAPHICALLY SPREAD HYBRID SOFTWARE DEVELOPMENT PROJECT

    Directory of Open Access Journals (Sweden)

    Святослав Аркадійович МУРАВЕЦЬКИЙ

    2016-02-01

    Full Text Available There have been discussed key points of operational activates in a large scale geographically spread software development projects. A look taken at required QA processes structure in such project. There have been given up to date methods of integration quality assurance processes into software development processes. There have been reviewed existing groups of software development methodologies. Such as sequential, agile and based on RPINCE2. There have been given a condensed overview of quality assurance processes in each group. There have been given a review of common challenges that sequential and agile models are having in case of large geographically spread hybrid software development project. Recommendations were given in order to tackle those challenges.  The conclusions about the best methodology choice and appliance to the particular project have been made.

  9. Cost estimation in software engineering projects with web components development

    Directory of Open Access Journals (Sweden)

    Javier de Andrés

    2015-01-01

    Full Text Available Existen multitud de modelos propuestos para la predicción de co stes en proyectos de software, al gunos orientados específicamen te para proyectos Web. Este trabajo analiza si los modelos específicos para proyectos Web están justifi cados, examinando el comportami ento diferencial de los costes entre proyectos de desarrollo softwar e Web y no Web. Se analizan dos aspectos del cálculo de costes: las deseconomías de escala, y el im pacto de algunas características de estos proyectos que son utilizadas como cost drivers. Se en uncian dos hipótesis: (a en estos proyect os las deseconomías de escala so n mayores y (b el incremento de coste que provocan los cost dr ivers es menor para los proyectos Web. Se contrastaron estas hipótesis a nalizando un conjunto de proyectos reales. Los resultados sugie ren que ambas hipótesis se cumplen. Por lo tanto, la principal contribu ción a la literatura de esta inv estigación es que el desarrollo de modelos específicos para los proyectos Web está justificado.

  10. Investigating the Practical Impact of Agile Practices on the Quality of Software Projects in Continuous Delivery

    OpenAIRE

    Olumide Akerele; Muthu Ramachandran; Mark Dixon

    2014-01-01

    Various factors affect the impact of agile factors on the continuous delivery of software projects. This is a major reason why projects perform differently- some failing and some succeeding- when they implement some agile practices in various environments. This is not helped by the fact that many projects work within limited budget while project plans also change-- making them to fall into some sort of pressure to meet deadline when they fall behind in their planned work. This study investiga...

  11. Design Issues for Traffic Management for the ATM UBR + Service for TCP Over Satellite Networks

    Science.gov (United States)

    Jain, Raj

    1999-01-01

    This project was a comprehensive research program for developing techniques for improving the performance of Internet protocols over Asynchronous Transfer Mode (ATM) based satellite networks. Among the service categories provided by ATM networks, the most commonly used category for data traffic is the unspecified bit rate (UBR) service. UBR allows sources to send data into the network without any feedback control. The project resulted in the numerous ATM Forum contributions and papers.

  12. Research on software systems dependability at the OECD Halden Reactor Project

    International Nuclear Information System (INIS)

    Sivertsen, Terje; Owre, Fridtjov

    2011-01-01

    Two central issues related to software systems dependability are those of safety integrity and safety demonstration. A proper understanding of these two issues are important for the selection of process, methods, techniques and tools to be used in the different life cycle phases of the software. Following a brief discussion on the concept of software safety integrity and its relationship to software systems dependability, this paper gives an introduction to research problems addressed by the OECD Halden Reactor Project within this area. The paper concludes with a discussion on the important role of safety demonstration in this context. (author)

  13. Software project effort estimation foundations and best practice guidelines for success

    CERN Document Server

    Trendowicz, Adam

    2014-01-01

    Software effort estimation is one of the oldest and most important problems in software project management, and thus today there are a large number of models, each with its own unique strengths and weaknesses in general, and even more importantly, in relation to the environment and context in which it is to be applied.Trendowicz and Jeffery present a comprehensive look at the principles of software effort estimation and support software practitioners in systematically selecting and applying the most suitable effort estimation approach. Their book not only presents what approach to take and how

  14. Research on cross - Project software defect prediction based on transfer learning

    Science.gov (United States)

    Chen, Ya; Ding, Xiaoming

    2018-04-01

    According to the two challenges in the prediction of cross-project software defects, the distribution differences between the source project and the target project dataset and the class imbalance in the dataset, proposing a cross-project software defect prediction method based on transfer learning, named NTrA. Firstly, solving the source project data's class imbalance based on the Augmented Neighborhood Cleaning Algorithm. Secondly, the data gravity method is used to give different weights on the basis of the attribute similarity of source project and target project data. Finally, a defect prediction model is constructed by using Trad boost algorithm. Experiments were conducted using data, come from NASA and SOFTLAB respectively, from a published PROMISE dataset. The results show that the method has achieved good values of recall and F-measure, and achieved good prediction results.

  15. RISK MANAGEMENT AUTOMATION OF SOFTWARE PROJECTS BASED ОN FUZZY INFERENCE

    Directory of Open Access Journals (Sweden)

    T. M. Zubkova

    2015-09-01

    Full Text Available Application suitability for one of the intelligent methods for risk management of software projects has been shown based on the review of existing algorithms for fuzzy inference in the field of applied problems. Information sources in the management of software projects are analyzed; major and minor risks are highlighted. The most critical parameters have been singled out giving the possibility to estimate the occurrence of an adverse situations (project duration, the frequency of customer’s requirements changing, work deadlines, experience of developers’ participation in such projects and others.. The method of qualitative fuzzy description based on fuzzy logic has been developed for analysis of these parameters. Evaluation of possible situations and knowledge base formation rely on a survey of experts. The main limitations of existing automated systems have been identified in relation to their applicability to risk management in the software design. Theoretical research set the stage for software system that makes it possible to automate the risk management process for software projects. The developed software system automates the process of fuzzy inference in the following stages: rule base formation of the fuzzy inference systems, fuzzification of input variables, aggregation of sub-conditions, activation and accumulation of conclusions for fuzzy production rules, variables defuzzification. The result of risk management automation process in the software design is their quantitative and qualitative assessment and expert advice for their minimization. Practical significance of the work lies in the fact that implementation of the developed automated system gives the possibility for performance improvement of software projects.

  16. Inequalities in Open Source Software Development: Analysis of Contributor’s Commits in Apache Software Foundation Projects

    Science.gov (United States)

    2016-01-01

    While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution. PMID:27096157

  17. Business Value Is not only Dollars : Results from Case Study Research on Agile Software Projects

    NARCIS (Netherlands)

    Racheva, Z.; Daneva, Maia; Sikkel, Nicolaas; Buglione, Luigi; Ali Babar, M.; Vierimaa, Matias; Oivo, Markku

    Business value is a key concept in agile software development. This paper presents results of a case study on how business value and its creation is perceived in the context of agile projects. Our overall conclusion is that the project participants almost never use an explicit and structured

  18. Conceptions of Software Development by Project Managers: A Study of Managing the Outsourced Development of Software Applications for United States Federal Government Agencies

    Science.gov (United States)

    Eisen, Daniel

    2013-01-01

    This study explores how project managers, working for private federal IT contractors, experience and understand managing the development of software applications for U.S. federal government agencies. Very little is known about how they manage their projects in this challenging environment. Software development is a complex task and only grows in…

  19. NASA's TReK Project: A Case Study in Using the Spiral Model of Software Development

    Science.gov (United States)

    Hendrix, T. Dean; Schneider, Michelle P.

    1998-01-01

    Software development projects face numerous challenges that threaten their successful completion. Whether it is not enough money, too little time, or a case of "requirements creep" that has turned into a full sprint, projects must meet these challenges or face possible disastrous consequences. A robust, yet flexible process model can provide a mechanism through which software development teams can meet these challenges head on and win. This article describes how the spiral model has been successfully tailored to a specific project and relates some notable results to date.

  20. Lessons learned applying CASE methods/tools to Ada software development projects

    Science.gov (United States)

    Blumberg, Maurice H.; Randall, Richard L.

    1993-01-01

    This paper describes the lessons learned from introducing CASE methods/tools into organizations and applying them to actual Ada software development projects. This paper will be useful to any organization planning to introduce a software engineering environment (SEE) or evolving an existing one. It contains management level lessons learned, as well as lessons learned in using specific SEE tools/methods. The experiences presented are from Alpha Test projects established under the STARS (Software Technology for Adaptable and Reliable Systems) project. They reflect the front end efforts by those projects to understand the tools/methods, initial experiences in their introduction and use, and later experiences in the use of specific tools/methods and the introduction of new ones.

  1. Fabrication and characterization of MCC [Materials Characterization Center] approved testing material---ATM-2, ATM-3, and ATM-4 glasses

    International Nuclear Information System (INIS)

    Wald, J.W.

    1988-03-01

    Materials Characterization Center glasses ATM-2, ATM-3, and ATM-4 are designed to simulate high-level waste glasses that are likely to result from the reprocessing of commercial nuclear reactor fuels. The three Approved Testing Materials (ATMs) are borosilicate glasses based upon the MCC-76-68 glass composition. One radioisotope was added to form each ATM. The radioisotopes added to form ATM-2, ATM-3, and ATM-4 were 241 Am, 237 Np, and 239 Pu, respectively. Each of the ATM lots was produced in a nominal lot size of 450 g from feed stock melted in a nitrogen-atmosphere glove box at 1200/degree/C in a platinum crucible. Each ATM was then cast into bars. Analyzed compositions of these glasses are listed. The nonradioactive elements were analyzed by inductively coupled argon plasma atomic emission spectroscopy (ICP), and the radioisotope analyses were done by alpha energy analysis. Results are discussed. 7 refs., 3 figs., 5 tabs

  2. Learning from open source software projects to improve scientific review.

    Science.gov (United States)

    Ghosh, Satrajit S; Klein, Arno; Avants, Brian; Millman, K Jarrod

    2012-01-01

    Peer-reviewed publications are the primary mechanism for sharing scientific results. The current peer-review process is, however, fraught with many problems that undermine the pace, validity, and credibility of science. We highlight five salient problems: (1) reviewers are expected to have comprehensive expertise; (2) reviewers do not have sufficient access to methods and materials to evaluate a study; (3) reviewers are neither identified nor acknowledged; (4) there is no measure of the quality of a review; and (5) reviews take a lot of time, and once submitted cannot evolve. We propose that these problems can be resolved by making the following changes to the review process. Distributing reviews to many reviewers would allow each reviewer to focus on portions of the article that reflect the reviewer's specialty or area of interest and place less of a burden on any one reviewer. Providing reviewers materials and methods to perform comprehensive evaluation would facilitate transparency, greater scrutiny, and replication of results. Acknowledging reviewers makes it possible to quantitatively assess reviewer contributions, which could be used to establish the impact of the reviewer in the scientific community. Quantifying review quality could help establish the importance of individual reviews and reviewers as well as the submitted article. Finally, we recommend expediting post-publication reviews and allowing for the dialog to continue and flourish in a dynamic and interactive manner. We argue that these solutions can be implemented by adapting existing features from open-source software management and social networking technologies. We propose a model of an open, interactive review system that quantifies the significance of articles, the quality of reviews, and the reputation of reviewers.

  3. ATM security via "Stargate" solution

    OpenAIRE

    Hensley, Katrina; Ludden, Fredrick

    1999-01-01

    Approved for public release, distribution unlimited. In today's world of integrating voice, video and data into a single network, Asynchronous Transfer Mode (ATM) networks have become prevalent in the Department of Defense. The Department of Defense's critical data will have to pass through public networks, which causes concern for security. This study presents an efficient solution aimed at authenticating communications over public ATM networks. The authenticating device, Stargate, utiliz...

  4. Connecting Remote Clusters with ATM

    Energy Technology Data Exchange (ETDEWEB)

    Hu, T.C.; Wyckoff, P.S.

    1998-10-01

    Sandia's entry into utilizing clusters of networked workstations is called Computational Plant or CPlant for short. The design of CPlant uses Ethernet to boot the individual nodes, Myrinet to communicate within a node cluster, and ATM to connect between remote clusters. This SAND document covers the work done to enable the use of ATM on the CPlant nodes in the Fall of 1997.

  5. Process for planning and control of software projects using XedroGESPRO

    OpenAIRE

    Jacqueline Marín-Sánchez; José Alejandro Lugo-García; Pedro Yobanis Piñero-Pérez; Alena María Santiesteban-García; Félix Noel Abelardo-Santana; Javier Menéndez-Rizo

    2014-01-01

    The software project management in Cuba has become a key area for improving production processes and decisionmaking in organizations. Several models and standards for process improvement, related with project management, proposed best practices on issues of planning and control of projects. However, they are generic guidelines that describe only those activities to execute, leaving the responsibility for implementing to organizations, using sometimes , expensive proprietary infor...

  6. Optimizing strategy software for repetitive construction projects within multi-mode resources

    Directory of Open Access Journals (Sweden)

    Remon Fayek Aziz

    2013-09-01

    Full Text Available Estimating tender data for specific project is the most essential part in construction areas as of contractor’s view such as: proposed project duration with corresponding gross value and cash flows. This paper focuses on how to calculate tender data using Optimizing Strategy Software (OSS for repetitive construction projects with identical activity’s duration in case of single number of crew such as: project duration, project/bid price, project maximum working capital, and project net present value of the studied project. A simplified multi-objective optimization software (OSS will be presented that creates best tender data to contractor compared with more feasible options generated from multi-mode resources in a given project. OSS is intended to give more scenarios which provide practical support for typical construction contractors who need to optimize resource utilization in order to minimize project duration, project/bid price, and project maximum working capital while maximizing its net present value simultaneously. OSS is designed by java programing code system to provide a number of new and unique capabilities, including: (1 Ranking the obtained optimal plans according to a set of planner specified weights representing the relative importance of duration, price, maximum working capital and net present value in the analyzed project; (2 Visualizing and viewing the generated optimal trade-off; and (3 Providing seamless integration with available project management calculations. In order to provide the aforementioned capabilities of OSS, the system is implemented and developed in four main modules: (1 A user interface module; (2 A database module; (3 A running module; (4 A connecting module. At the end of the paper, an illustrative example will be presented to demonstrate and verify the applications of the proposed software (OSS to an optimization expressway of repetitive construction project.

  7. ATM Coastal Topography-Mississippi, 2001

    Science.gov (United States)

    Nayegandhi, Amar; Yates, Xan; Brock, John C.; Sallenger, A.H.; Klipp, Emily S.; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived first-surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the Mississippi coastline, from Lakeshore to Petit Bois Island, acquired September 9-10, 2001. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative scanning lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS

  8. ATM Coastal Topography-Alabama 2001

    Science.gov (United States)

    Nayegandhi, Amar; Yates, Xan; Brock, John C.; Sallenger, A.H.; Bonisteel, Jamie M.; Klipp, Emily S.; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of Lidar-derived first surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the Alabama coastline, acquired October 3-4, 2001. The datasets are made available for use as a management tool to research scientists and natural resource managers. An innovative scanning Lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning Lidar system that measures high-resolution topography of the land surface, and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of Lidar data in an interactive or batch mode. Modules for pre-survey flight line definition, flight path plotting, Lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is routinely used to create maps that

  9. Cross-border software development of health information system: A case study on project between India and Pakistan based on open source software

    OpenAIRE

    Sabir, Uzma

    2017-01-01

    Global software development is a phenomenon that is receiving considerable interest from researchers during past two decades. Several challenges have been identified and approaches to deal with these challenges have been developed. Typically, western companies outsource their projects to countries where costs are lower and skilled professionals are easily available. Majority of these projects are developed for commercial purposes. However, software development projects between India and Pakis...

  10. A CMMI-based approach for medical software project life cycle study.

    Science.gov (United States)

    Chen, Jui-Jen; Su, Wu-Chen; Wang, Pei-Wen; Yen, Hung-Chi

    2013-01-01

    In terms of medical techniques, Taiwan has gained international recognition in recent years. However, the medical information system industry in Taiwan is still at a developing stage compared with the software industries in other nations. In addition, systematic development processes are indispensable elements of software development. They can help developers increase their productivity and efficiency and also avoid unnecessary risks arising during the development process. Thus, this paper presents an application of Light-Weight Capability Maturity Model Integration (LW-CMMI) to Chang Gung Medical Research Project (CMRP) in the Nuclear medicine field. This application was intended to integrate user requirements, system design and testing of software development processes into three layers (Domain, Concept and Instance) model. Then, expressing in structural System Modeling Language (SysML) diagrams and converts part of the manual effort necessary for project management maintenance into computational effort, for example: (semi-) automatic delivery of traceability management. In this application, it supports establishing artifacts of "requirement specification document", "project execution plan document", "system design document" and "system test document", and can deliver a prototype of lightweight project management tool on the Nuclear Medicine software project. The results of this application can be a reference for other medical institutions in developing medical information systems and support of project management to achieve the aim of patient safety.

  11. Gigabit ATM: another technical mistake?

    Science.gov (United States)

    Christ, Paul

    1998-09-01

    Once upon a time, or more precisely during February 1988 at the CCITT Seoul plenary, and definitely arriving as a revolution, ATM hit the hard-core B-ISDN circuit-switching gang. Initiated by the Telecoms' camp, but, surprisingly, soon to be pushed by computer minded people, ATM's generic technological history is somewhat richer than single-sided stories. Here are two classical elements of that history: Firstly, together with X.25, ATM suffers from the connection versus datagram dichotomy, well known for more than twenty years. Secondly, and lesser known, ATM's use of cells in support of the 'I' of B-ISDN was questioned from the very beginning by the packet switching camp. Furthermore, in this context, there are two other essential elements to be considered: Firstly, the exponential growth of the Internet and later intranets, using Internet technology, sparked by the success of the Web and the WINTEL alliance, resulted in a corresponding demand for both aggregate and end-system network bandwidth. Secondly, servers, historically restricted to the exclusive club of HIPPI-equipped supercomputers, suddenly become ordinary high-end PCs with 64-bit wide PCI busses -- definitely aiming at the Gigabit. Here, if your aim is for Gigabit ATM with 5000-transactions per second classical supercomputers, a 65K ATM MTU -- as implemented by Cray -- might be okay. Following Clark and others, another part of the story is the adoption and redefinition, by the IETF, of the Telecoms' notion of 'Integrated Services' and QoS mechanisms. The quest for low-delay IP packet forwarding, perhaps possible over ATM cut-throughs, has resulted in the switching versus/or integrated-with-routing movement. However, a blow for ATM may be the recent results concerning fast routing table lookup algorithms. This, by making Gigabit routing possible using ordinary Pentium processors may eventually render the much prophesized ATM switching performance unnecessary. Recently, with the rise of Gigabit Ethernet

  12. Software for improving the quality of project management, a case study: international manufacture of electrical equipment

    Science.gov (United States)

    Preradović, D. M.; Mićić, Lj S.; Barz, C.

    2017-05-01

    Production conditions in today’s world require software support at every stage of production and development of new products, for quality assurance and compliance with ISO standards. In addition to ISO standards such as usual metrics of quality, companies today are focused on other optional standards, such as CMMI (Capability Maturity Model Integrated) or prescribing they own standards. However, while there is intensive progress being made in the PM (project management), there is still a significant number of projects, at the global level, that are failures. These have failed to achieve their goals, within budget or timeframe. This paper focuses on checking the role of software tools through the rate of success in projects implemented in the case of internationally manufactured electrical equipment. The results of this research show the level of contribution of the project management software used to manage and develop new products to improve PM processes and PM functions, and how selection of the software tools affects the quality of PM processes and successfully completed projects.

  13. Integrated management tool for controls software problems, requests and project tasking at SLAC

    International Nuclear Information System (INIS)

    Rogind, D.; Allen, W.; Colocho, W.; DeContreras, G.; Gordon, J.; Pandey, P.; Shoaee, H.

    2012-01-01

    The Accelerator Directorate (AD) Instrumentation and Controls (ICD) Software (SW) Department at SLAC, with its service center model, continuously receives engineering requests to design, build and support controls for accelerator systems lab-wide. Each customer request can vary in complexity from a small software engineering change to a major enhancement. SLAC's Accelerator Improvement Projects (AIPs), along with DOE Construction projects, also contribute heavily to the work load. The various customer requests and projects, paired with the ongoing operational maintenance and problem reports, place a demand on the department that consistently exceeds the capacity of available resources. A centralized repository - comprised of all requests, project tasks, and problems - available to physicists, operators, managers, and engineers alike, is essential to capture, communicate, prioritize, assign, schedule, track, and finally, commission all work components. The Software Department has recently integrated request / project tasking into SLAC's custom online problem tracking 'Comprehensive Accelerator Tool for Enhancing Reliability' (CATER) tool. This paper discusses the newly implemented software request management tool - the workload it helps to track, its structure, features, reports, work-flow and its many usages. (authors)

  14. A View on a Successful International Educational Project in Software Engineering

    Directory of Open Access Journals (Sweden)

    Zoran Budimac

    2012-01-01

    Full Text Available In this paper, a successful and fruitful joint project will be presented. The project joins participants from 9 countries and from 15 universities. Since it started in 2001, this project entitled “Software Engineering: Computer Science Education and Research Cooperation” helped participants to gain excellent, up to date educational material, apply modern teaching methods, exchange experiences with other participants, and work jointly on the further development of lectures, case-studies, assignments, examination questions, and other necessary elements of a course. Project works under auspices of Stability Pact of South-Eastern Europe, and is supported by DAAD. The project started with the creation of a common beginning course in “Software Engineering”, but over time it grew and the number of other courses was developed. Finished almost completely are the courses in “Object-oriented programming”, “Software Project Management”, “Advanced Compiler Construction”, and “Data Structures and Algorithms”, and some other courses are under development. Aside from the educational collaboration, project members also developed good scientific cooperation, and published several research papers.

  15. Engineering a large application software project: the controls of the CERN PS accelerator complex

    International Nuclear Information System (INIS)

    Benincasa, G.P.; Daneels, A.; Heymans, P.; Serre, Ch.

    1985-01-01

    The CERN PS accelerator complex has been progressively converted to full computer controls without interrupting its full-time operation (more than 6000 hours per year with on average not more than 1% of the total down-time due to controls). The application software amounts to 120 man-years and 450'000 instructions: it compares with other large software projects, also outside the accelerator world: e.g. Skylab's ground support software. This paper outlines the application software structure which takes into account technical requirements and constraints (resulting from the complexity of the process and its operation) and economical and managerial ones. It presents the engineering and management techniques used to promote implementation, testing and commissioning within budget, manpower and time constraints and concludes with experience gained

  16. Fuzzy system for risk analysis in software projects through the attributes of quality standards iso 25000

    Directory of Open Access Journals (Sweden)

    Chau Sen Shia

    2014-02-01

    Full Text Available With the growth in demand for products and services in the IT area, companies encounter difficulties in establishing a metric or measure of quality of services to address measurably qualitative values in their planning. In this work fuzzy logic, standard SQuaRE (measurement of the quality of software products, Likertscale, GQM method (Goal-Question-Metric -indicator of quality of Software and the project risk analysis model of Boehm were used to assess the quality of services and decision-making, according to your demand and requests for software development. With the aim of improving the quality in the provision of services, the application is used to integrate the team and follow the life cycle of a project from its initial phase, and to assist in the comparison with the proposed schedule during the requirements elicitation.

  17. Modelling the critical success factors of agile software development projects in South Africa

    Directory of Open Access Journals (Sweden)

    Tawanda B. Chiyangwa

    2017-10-01

    Full Text Available Background: The continued in failure of agile and traditional software development projects have led to the consideration, attention and dispute to critical success factors that are the aspects which are most vital to make a software engineering methodology fruitful. Although there is an increasing variety of critical success factors and methodologies, the conceptual frameworks which have causal relationship are limited. Objective: The objective of this study was to identify and provide insights into the critical success factors that influence the success of software development projects using agile methodologies in South Africa. Method: Quantitative method of collecting data was used. Data were collected in South Africa through a Web-based survey using structured questionnaires. Results: These results show that organisational factors have a great influence on performance expectancy characteristics. Conclusion: The results of this study discovered a comprehensive model that could provide guidelines to the agile community and to the agile professionals.

  18. A Constrained and Guided Approach for Managing Software Engineering Course Projects

    Science.gov (United States)

    Cheng, Y.-P.; Lin, J. M.-C.

    2010-01-01

    This paper documents several years of experimentation with a new approach to organizing and managing projects in a software engineering course. The initial failure and subsequent refinements that the new approach has been through since 2004 are described herein. The "constrained and guided" approach, as it is called, has helped to reduce…

  19. Software for relativistic atomic structure theory: The grasp project at oxford

    International Nuclear Information System (INIS)

    Parpia, F.A.; Grant, I.P.

    1991-01-01

    GRASP is an acronym for General-purpose Relativistic Atomic Structure Program. The objective of the GRASP project at Oxford is to produce user-friendly state-of-the-art multiconfiguration Dirac-Fock (MCDF) software packages for rleativistic atomic structure theory

  20. Enhance Learning on Software Project Management through a Role-Play Game in a Virtual World

    Science.gov (United States)

    Maratou, Vicky; Chatzidaki, Eleni; Xenos, Michalis

    2016-01-01

    This article presents a role-play game for software project management (SPM) in a three-dimensional online multiuser virtual world. The Opensimulator platform is used for the creation of an immersive virtual environment that facilitates students' collaboration and realistic interaction, in order to manage unexpected events occurring during the…

  1. Development of the Advanced Technology Microwave Sounder (ATMS) for NPOESS C1

    Science.gov (United States)

    Brann, C.; Kunkee, D.

    2008-12-01

    The National Polar-orbiting Operational Environmental Satellite System's Advanced Technology Microwave Sounder (ATMS) is planned for flight on the first NPOESS mission (C1) in 2013. The C1 ATMS will be the second instrument of the ATMS series and will provide along with the companion Cross-track Infrared Sounder (CrIS), atmospheric temperature and moisture profiles for NPOESS. The first flight of the ATMS is scheduled in 2010 on the NPOESS Preparatory Project (NPP) satellite, which is an early instrument risk reduction component of the NPOESS mission. This poster will focus on the development of the ATMS for C1 including aspects of the sensor calibration, antenna beam and RF characteristics and scanning. New design aspects of the C1 ATMS, required primarily by parts obsolescence, will also be addressed in this poster.

  2. AN ENHANCED MODEL TO ESTIMATE EFFORT, PERFORMANCE AND COST OF THE SOFTWARE PROJECTS

    Directory of Open Access Journals (Sweden)

    M. Pauline

    2013-04-01

    Full Text Available The Authors have proposed a model that first captures the fundamentals of software metrics in the phase 1 consisting of three primitive primary software engineering metrics; they are person-months (PM, function-points (FP, and lines of code (LOC. The phase 2 consists of the proposed function point which is obtained by grouping the adjustment factors to simplify the process of adjustment and to ensure more consistency in the adjustments. In the proposed method fuzzy logic is used for quantifying the quality of requirements and is added as one of the adjustment factor, thus a fuzzy based approach for the Enhanced General System Characteristics to Estimate Effort of the Software Projects using productivity has been obtained. The phase 3 takes the calculated function point from our work and is given as input to the static single variable model (i.e. to the Intermediate COCOMO and COCOMO II for cost estimation. The Authors have tailored the cost factors in intermediate COCOMO and both; cost and scale factors are tailored in COCOMO II to suite to the individual development environment, which is very important for the accuracy of the cost estimates. The software performance indicators are project duration, schedule predictability, requirements completion ratio and post-release defect density, are also measured for the software projects in my work. A comparative study for effort, performance measurement and cost estimation of the software project is done between the existing model and the authors proposed work. Thus our work analyzes the interaction¬al process through which the estimation tasks were collectively accomplished.

  3. Network, system, and status software enhancements for the autonomously managed electrical power system breadboard. Volume 1: Project summary

    Science.gov (United States)

    Mckee, James W.

    1990-01-01

    This volume (1 of 4) gives a summary of the original AMPS software system configuration, points out some of the problem areas in the original software design that this project is to address, and in the appendix collects all the bimonthly status reports. The purpose of AMPS is to provide a self reliant system to control the generation and distribution of power in the space station. The software in the AMPS breadboard can be divided into three levels: the operating environment software, the protocol software, and the station specific software. This project deals only with the operating environment software and the protocol software. The present station specific software will not change except as necessary to conform to new data formats.

  4. A TAD closer to ATM.

    Science.gov (United States)

    Aymard, Francois; Legube, Gaëlle

    2016-05-01

    Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy.

  5. Wireless Connectivity to ATM Communication Grid

    National Research Council Canada - National Science Library

    Rajaravivarma, Veeramuthu

    1998-01-01

    The AFOSR funds were used to purchase a 12 port Fore ATM switch, ATM network interface cards, a SUN UltraSPARC workstation, Lucent WavePoint wireless bridge, and Lucent WaveLAN wireless network interface cards...

  6. Effects of the Meetings-Flow Approach on Quality Teamwork in the Training of Software Capstone Projects

    Science.gov (United States)

    Chen, Chung-Yang; Hong, Ya-Chun; Chen, Pei-Chi

    2014-01-01

    Software development relies heavily on teamwork; determining how to streamline this collaborative development is an essential training subject in computer and software engineering education. A team process known as the meetings-flow (MF) approach has recently been introduced in software capstone projects in engineering programs at various…

  7. A Systematic Mapping on Supporting Approaches for Requirements Traceability in the Context of Software Projects

    Directory of Open Access Journals (Sweden)

    MALCHER, P R.C.

    2015-12-01

    Full Text Available The Requirements Traceability is seen as a quality factor with regard to software development, being present in standards and quality models. In this context, several techniques, models, frameworks and tools have been used to support it. Thus, the purpose of this paper is to present a systematic mapping carried out in order to find in the literature approaches to support the requirements traceability in the context of software projects and make the categorization of the data found in order to demonstrate, by means of a reliable, accurate and auditable method, how this area has developed and what are the main approaches are used to implement it.

  8. NPP ATMS Snowfall Rate Product

    Science.gov (United States)

    Meng, Huan; Ferraro, Ralph; Kongoli, Cezar; Wang, Nai-Yu; Dong, Jun; Zavodsky, Bradley; Yan, Banghua

    2015-01-01

    Passive microwave measurements at certain high frequencies are sensitive to the scattering effect of snow particles and can be utilized to retrieve snowfall properties. Some of the microwave sensors with snowfall sensitive channels are Advanced Microwave Sounding Unit (AMSU), Microwave Humidity Sounder (MHS) and Advance Technology Microwave Sounder (ATMS). ATMS is the follow-on sensor to AMSU and MHS. Currently, an AMSU and MHS based land snowfall rate (SFR) product is running operationally at NOAA/NESDIS. Based on the AMSU/MHS SFR, an ATMS SFR algorithm has been developed recently. The algorithm performs retrieval in three steps: snowfall detection, retrieval of cloud properties, and estimation of snow particle terminal velocity and snowfall rate. The snowfall detection component utilizes principal component analysis and a logistic regression model. The model employs a combination of temperature and water vapor sounding channels to detect the scattering signal from falling snow and derive the probability of snowfall (Kongoli et al., 2015). In addition, a set of NWP model based filters is also employed to improve the accuracy of snowfall detection. Cloud properties are retrieved using an inversion method with an iteration algorithm and a two-stream radiative transfer model (Yan et al., 2008). A method developed by Heymsfield and Westbrook (2010) is adopted to calculate snow particle terminal velocity. Finally, snowfall rate is computed by numerically solving a complex integral. NCEP CMORPH analysis has shown that integration of ATMS SFR has improved the performance of CMORPH-Snow. The ATMS SFR product is also being assessed at several NWS Weather Forecast Offices for its usefulness in weather forecast.

  9. Molecular Imaging of the ATM Kinase Activity

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Terence M. [Department of Radiation Oncology, Ohio State University, Columbus, Ohio (United States); Nyati, Shyam [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Center for Molecular Imaging, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Ross, Brian D. [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Rehemtulla, Alnawaz, E-mail: alnawaz@umich.edu [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Center for Molecular Imaging, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan (United States)

    2013-08-01

    Purpose: Ataxia telangiectasia mutated (ATM) is a serine/threonine kinase critical to the cellular DNA-damage response, including from DNA double-strand breaks. ATM activation results in the initiation of a complex cascade of events including DNA damage repair, cell cycle checkpoint control, and survival. We sought to create a bioluminescent reporter that dynamically and noninvasively measures ATM kinase activity in living cells and subjects. Methods and Materials: Using the split luciferase technology, we constructed a hybrid cDNA, ATM-reporter (ATMR), coding for a protein that quantitatively reports on changes in ATM kinase activity through changes in bioluminescence. Results: Treatment of ATMR-expressing cells with ATM inhibitors resulted in a dose-dependent increase in bioluminescence activity. In contrast, induction of ATM kinase activity upon irradiation resulted in a decrease in reporter activity that correlated with ATM and Chk2 activation by immunoblotting in a time-dependent fashion. Nuclear targeting improved ATMR sensitivity to both ATM inhibitors and radiation, whereas a mutant ATMR (lacking the target phosphorylation site) displayed a muted response. Treatment with ATM inhibitors and small interfering (si)RNA-targeted knockdown of ATM confirm the specificity of the reporter. Using reporter expressing xenografted tumors demonstrated the ability of ATMR to report in ATM activity in mouse models that correlated in a time-dependent fashion with changes in Chk2 activity. Conclusions: We describe the development and validation of a novel, specific, noninvasive bioluminescent reporter that enables monitoring of ATM activity in real time, in vitro and in vivo. Potential applications of this reporter include the identification and development of novel ATM inhibitors or ATM-interacting partners through high-throughput screens and in vivo pharmacokinetic/pharmacodynamic studies of ATM inhibitors in preclinical models.

  10. Predicting Defects Using Information Intelligence Process Models in the Software Technology Project.

    Science.gov (United States)

    Selvaraj, Manjula Gandhi; Jayabal, Devi Shree; Srinivasan, Thenmozhi; Balasubramanie, Palanisamy

    2015-01-01

    A key differentiator in a competitive market place is customer satisfaction. As per Gartner 2012 report, only 75%-80% of IT projects are successful. Customer satisfaction should be considered as a part of business strategy. The associated project parameters should be proactively managed and the project outcome needs to be predicted by a technical manager. There is lot of focus on the end state and on minimizing defect leakage as much as possible. Focus should be on proactively managing and shifting left in the software life cycle engineering model. Identify the problem upfront in the project cycle and do not wait for lessons to be learnt and take reactive steps. This paper gives the practical applicability of using predictive models and illustrates use of these models in a project to predict system testing defects thus helping to reduce residual defects.

  11. ATM in Europe: analysis of current status

    DEFF Research Database (Denmark)

    1999-01-01

    This deliverable provides an overview of the current status of the European market for ATM services. The offer of ATM services by principal operators in Belgium, Denmark, Finland, France, Germany, Greece, Italy, Norway, Portugal, Spain, Sweden and United Kingdom is described. In addition, a number...... of international providers of ATM in Europe are presented....

  12. Historical Post Office Directory Parser (POD Parser Software From the AddressingHistory Project

    Directory of Open Access Journals (Sweden)

    Nicola Osborne

    2014-07-01

    Full Text Available The POD Parser is Python software for parsing the OCR’d (optical character recognised text of digitised historical Scottish Post Office Directories (PODs to produce a consistent structured format for the data and for geocoding each address. The software was developed as part of the AddressingHistory project which sought to combine digitised historic directories with digitised and georeferenced historic maps.  The software has potential for reuse in multiple research contexts where historical post office directory data is relevant, and is therefore particularly of use in historical research into social, economic or demographic trends. The POD Parser is currently designed for use with Scottish directories but is extensible, perhaps with some adaptation, to use with other similarly formatted materials such as the English Trade Directories.

  13. The D2G2 project: a new software tool for nuclear engineering design in Canada

    International Nuclear Information System (INIS)

    Rheaume, P.; Lefebvre, J.F.; Roy, R.; Koclas, J.

    2004-01-01

    Nowadays, high quality neutronic simulation codes are readily available. The open source software suite DRAGON/DONJON is a good example. It is free, it has proven quality and correctness over the years and is still developed and maintained at Ecole Polytechnique de Montreal. However, most simulation codes have the following weaknesses: limited usability, poor maintainability, no internal data standardization and poor portability. The D2G2 project is a software development initiative which aims to create an upper layer software tool that annihilates the weakness of classic simulation codes. This paper presents D2G2Client's and D2G2Server's principal capabilities, how they interact and the libraries they use. (author)

  14. Software Process Improvement through the Removal of Project-Level Knowledge Flow Obstacles: The Perceptions of Software Engineers

    Science.gov (United States)

    Mitchell, Susan Marie

    2012-01-01

    Uncontrollable costs, schedule overruns, and poor end product quality continue to plague the software engineering field. Innovations formulated with the expectation to minimize or eliminate cost, schedule, and quality problems have generally fallen into one of three categories: programming paradigms, software tools, and software process…

  15. BMR: Benchmarking Metrics Recommender for Personnel issues in Software Development Projects

    Directory of Open Access Journals (Sweden)

    Angel Garcia-Crespo

    2009-12-01

    Full Text Available This paper presents an architecture which applies document similarity measures to the documentation produced during the phases of software development in order to generate recommendations of process and people metrics for similar projects. The application makes a judgment of similarity of the Service Provision Offer (SPO document of a new proposed project to a collection of Project History Documents (PHD, stored in a repository of unstructured texts. The process is carried out in three stages: firstly, clustering of the Offer document with the set of PHDs which are most similar to it; this provides the initial indication of whether similar previous projects exist, and signifies similarity. Secondly, determination of which PHD in the set is most comparable with the Offer document, based on various parameters: project effort, project duration (time, project resources (members/size of team, costs, and sector(s involved, indicating comparability of projects. The comparable parameters are extracted using the GATE Natural Language Processing architecture. Lastly, a recommendation of metrics for the new project is made, which is based on the transferability of the metrics of the most similar and comparable PHD extracted, here referred to as recommendation.

  16. Software and man-machine interface considerations for a nuclear plant computer replacement and upgrade project

    International Nuclear Information System (INIS)

    Diamond, G.; Robinson, E.

    1984-01-01

    Some of the key software functions and Man-Machine Interface considerations in a computer replacement and upgrade project for a nuclear power plant are described. The project involves the installation of two separate computer systems: an Emergency Response Facilities Computer System (ERFCS) and a Plant Process Computer System (PPCS). These systems employ state-of-the-art computer hardware and software. The ERFCS is a new system intended to provide enhanced functions to meet NRC post-TMI guidelines. The PPCS is intended to replace and upgrade an existing obsolete plant computer system. A general overview of the hardware and software aspects of the replacement and upgrade is presented. The work done to develop the upgraded Man-Machine Interface is described. For the ERFCS, a detailed discussion is presented of the work done to develop logic to evaluate the readiness and performance of safety systems and their supporting functions. The Man-Machine Interface considerations of reporting readiness and performance to the operator are discussed. Finally, the considerations involved in the implementation of this logic in real-time software are discussed.. For the PPCS, a detailed discussion is presented of some new features

  17. A microprocessor card software server to support the Quebec health microprocessor card project.

    Science.gov (United States)

    Durant, P; Bérubé, J; Lavoie, G; Gamache, A; Ardouin, P; Papillon, M J; Fortin, J P

    1995-01-01

    The Quebec Health Smart Card Project is advocating the use of a memory card software server[1] (SCAM) to implement a portable medical record (PMR) on a smart card. The PMR is viewed as an object that can be manipulated by SCAM's services. In fact, we can talk about a pseudo-object-oriented approach. This software architecture provides a flexible and evolutive way to manage and optimize the PMR. SCAM is a generic software server; it can manage smart cards as well as optical (laser) cards or other types of memory cards. But, in the specific case of the Quebec Health Card Project, SCAM is used to provide services between physicians' or pharmacists' software and IBM smart card technology. We propose to expose the concepts and techniques used to provide a generic environment to deal with smart cards (and more generally with memory cards), to obtain a dynamic an evolutive PMR, to raise the system global security level and the data integrity, to optimize significantly the management of the PMR, and to provide statistic information about the use of the PMR.

  18. Madagascar: open-source software project for multidimensional data analysis and reproducible computational experiments

    Directory of Open Access Journals (Sweden)

    Sergey Fomel

    2013-11-01

    Full Text Available The Madagascar software package is designed for analysis of large-scale multidimensional data, such as those occurring in exploration geophysics. Madagascar provides a framework for reproducible research. By “reproducible research” we refer to the discipline of attaching software codes and data to computational results reported in publications. The package contains a collection of (a computational modules, (b data-processing scripts, and (c research papers. Madagascar is distributed on SourceForge under a GPL v2 license https://sourceforge.net/projects/rsf/. By October 2013, more than 70 people from different organizations around the world have contributed to the project, with increasing year-to-year activity. The Madagascar website is http://www.ahay.org/.

  19. A Data Specification for Software Project Performance Measures: Results of a Collaboration on Performance Measurement

    Science.gov (United States)

    2008-07-01

    cycle Evolution of a system, product, service, project or other human-made entity from conception through retirement [ ISO 12207 ]. Logical line of...012 [ ISO 1995] International Organization for Standardization. ISO /IEC 12207 :1995—Information technology— Software life cycle processes. http...definitions, authors were asked to use or align with already existing standards such as those available through ISO and IEEE when possible. Literature

  20. ProjectQ: An Open Source Software Framework for Quantum Computing

    OpenAIRE

    Steiger, Damian S.; Häner, Thomas; Troyer, Matthias

    2016-01-01

    We introduce ProjectQ, an open source software effort for quantum computing. The first release features a compiler framework capable of targeting various types of hardware, a high-performance simulator with emulation capabilities, and compiler plug-ins for circuit drawing and resource estimation. We introduce our Python-embedded domain-specific language, present the features, and provide example implementations for quantum algorithms. The framework allows testing of quantum algorithms through...

  1. Software pi/4 DQPSK Modem: A Student Project Using the TMS320-C6201 EVM Board

    OpenAIRE

    Weiss, S; Braithwaite, SJ; Stewart, RD

    2000-01-01

    This paper reports on a student project performed at the University of Southampton jointly by 4th year MEng students within the course "Advanced Radio Communications". The aim was to design a software modem capable of transmitting 16kb/s of data, whereby random number generation, advanced modulation, pulse shaping, synchronisation, and error counting techniques had to be applied. The ultimate aim was the implementation on a Texas Instruments TMS320-C6201 EVM board, which dictated some of the ...

  2. Waste receiving and processing facility module 1 data management system software project management plan

    International Nuclear Information System (INIS)

    Clark, R.E.

    1994-01-01

    This document provides the software development plan for the Waste Receiving and Processing (WRAP) Module 1 Data Management System (DMS). The DMS is one of the plant computer systems for the new WRAP 1 facility (Project W-026). The DMS will collect, store, and report data required to certify the low level waste (LLW) and transuranic (TRU) waste items processed at WRAP 1 as acceptable for shipment, storage, or disposal

  3. Redes Atm de Alto Desempenho

    Directory of Open Access Journals (Sweden)

    Flávia Oliveira Santos de Sá Lisboa

    2015-12-01

    Full Text Available A tendência atual de integração de serviços de dados, voz e vídeo, estimulada pelo pleno sucesso da Internet, aumentou a demanda por maior banda e melhor desempenho nas redes de comunicação de dados. Neste contexto, a tecnologia ATM (Asynchronous Transfer Mode vem sendo utilizada na implementação de backbone de LANs e WANs, justamente por oferecer a possibilidade de integração de serviços com qualidade, alta escalabilidade e altas taxas de transferência em banda larga. Neste artigo serão abordados os principais conceitos relacionados à tecnologia ATM, suas vantagens e desvantagens em face de outras tecnologias (como Fast e Gigabit Ethernet, além de casos de sua utilização em empresas e instituições de ensino.

  4. Simplified management of ATM traffic

    Science.gov (United States)

    Luoma, Marko; Ilvesmaeki, Mika

    1997-10-01

    ATM has been under a thorough standardization process for more than ten years. Looking at it now, what have we achieved during this time period? Originally ATM was meant to be an easy and efficient protocol enabling varying services over a single network. What it is turning to be it `yet another ISDN'--network full of hopes and promises but too difficult to implement and expensive to market. The fact is that more and more `nice features' are implemented on the cost of overloading network with hard management procedures. Therefore we need to adopt a new approach. This approach keeps a strong reminder on `what is necessary.' This paper presents starting points for an alternative approach to the traffic management. We refer to this approach as `the minimum management principle.' Choosing of the suitable service classes for the ATM network is made difficult by the fact that the more services one implements the more management he needs. This is especially true for the variable bit rate connections that are usually treated based on the stochastic models. Stochastic model, at its best, can only reveal momentary characteristics in the traffic stream not the long range behavior of it. Our assumption is that ATM will move towards Internet in the sense that strict values for quality make little or no sense in the future. Therefore stochastic modeling of variable bit rate connections seems to be useless. Nevertheless we see that some traffic needs to have strict guarantees and that the only economic way of doing so is to use PCR allocation.

  5. The state and profile of open source software projects in health and medical informatics.

    Science.gov (United States)

    Janamanchi, Balaji; Katsamakas, Evangelos; Raghupathi, Wullianallur; Gao, Wei

    2009-07-01

    Little has been published about the application profiles and development patterns of open source software (OSS) in health and medical informatics. This study explores these issues with an analysis of health and medical informatics related OSS projects on SourceForge, a large repository of open source projects. A search was conducted on the SourceForge website during the period from May 1 to 15, 2007, to identify health and medical informatics OSS projects. This search resulted in a sample of 174 projects. A Java-based parser was written to extract data for several of the key variables of each project. Several visually descriptive statistics were generated to analyze the profiles of the OSS projects. Many of the projects have sponsors, implying a growing interest in OSS among organizations. Sponsorship, we discovered, has a significant impact on project success metrics. Nearly two-thirds of the projects have a restrictive license type. Restrictive licensing may indicate tighter control over the development process. Our sample includes a wide range of projects that are at various stages of development (status). Projects targeted towards the advanced end user are primarily focused on bio-informatics, data formats, database and medical science applications. We conclude that there exists an active and thriving OSS development community that is focusing on health and medical informatics. A wide range of OSS applications are in development, from bio-informatics to hospital information systems. A profile of OSS in health and medical informatics emerges that is distinct and unique to the health care field. Future research can focus on OSS acceptance and diffusion and impact on cost, efficiency and quality of health care.

  6. Médicarte software developed for the Quebec microprocessor health card project.

    Science.gov (United States)

    Lavoie, G; Tremblay, L; Durant, P; Papillon, M J; Bérubé, J; Fortin, J P

    1995-01-01

    The Quebec Patient Smart Card Project is a Provincial Government initiative under the responsibility of the Rgie de l'assurance-maladie du Québec (Quebec Health Insurance Board). Development, implementation, and assessment duties were assigned to a team from Université Laval, which in turn joined a group from the Direction de la santé publique du Bas-St-Laurent in Rimouski, where the experiment is taking place. The pilot project seeks to evaluate the use and acceptance of a microprocessor card as a way to improve the exchange of clinical information between card users and various health professionals. The card can be best described as a résumé containing information pertinent to an individual's health history. It is not a complete medical file; rather, it is a summary to be used as a starting point for a discussion between health professionals and patients. The target population is composed of persons 60 years and over, pregnant women, infants under 18 months, and the residents of a small town located in the target area, St-Fabien, regardless of age. The health professionals involved are general practitioners, specialists, pharmacists, nurses, and ambulance personnel. Participation in the project is on a voluntary basis. Each health care provider participating in the project has a personal identification number (PIN) and must use both an access card and a user card to access information. This prevents unauthorized access to a patient's card and allows the staff to sign and date information entered onto the patient card. To test the microprocessor card, we developed software based on a problem-oriented approach integrating diagnosis, investigations, treatments, and referrals. This software is not an expert system that constrains the clinician to a particular decisional algorithm. Instead, the software supports the physician in decision making. The software was developed with a graphical interface (Windows 3.1) to maximize its user friendliness. A version of the

  7. Designing for Change: Minimizing the Impact of Changing Requirements in the Later Stages of a Spaceflight Software Project

    Science.gov (United States)

    Allen, B. Danette

    1998-01-01

    In the traditional 'waterfall' model of the software project life cycle, the Requirements Phase ends and flows into the Design Phase, which ends and flows into the Development Phase. Unfortunately, the process rarely, if ever, works so smoothly in practice. Instead, software developers often receive new requirements, or modifications to the original requirements, well after the earlier project phases have been completed. In particular, projects with shorter than ideal schedules are highly susceptible to frequent requirements changes, as the software requirements analysis phase is often forced to begin before the overall system requirements and top-level design are complete. This results in later modifications to the software requirements, even though the software design and development phases may be complete. Requirements changes received in the later stages of a software project inevitably lead to modification of existing developed software. Presented here is a series of software design techniques that can greatly reduce the impact of last-minute requirements changes. These techniques were successfully used to add built-in flexibility to two complex software systems in which the requirements were expected to (and did) change frequently. These large, real-time systems were developed at NASA Langley Research Center (LaRC) to test and control the Lidar In-Space Technology Experiment (LITE) instrument which flew aboard the space shuttle Discovery as the primary payload on the STS-64 mission.

  8. Calculator: A Hardware Design, Math and Software Programming Project Base Learning

    Directory of Open Access Journals (Sweden)

    F. Criado

    2015-03-01

    Full Text Available This paper presents the implementation by the students of a complex calculator in hardware. This project meets hardware design goals, and also highly motivates them to use competences learned in others subjects. The learning process, associated to System Design, is hard enough because the students have to deal with parallel execution, signal delay, synchronization … Then, to strengthen the knowledge of hardware design a methodology as project based learning (PBL is proposed. Moreover, it is also used to reinforce cross subjects like math and software programming. This methodology creates a course dynamics that is closer to a professional environment where they will work with software and mathematics to resolve the hardware design problems. The students design from zero the functionality of the calculator. They are who make the decisions about the math operations that it is able to resolve it, and also the operands format or how to introduce a complex equation into the calculator. This will increase the student intrinsic motivation. In addition, since the choices may have consequences on the reliability of the calculator, students are encouraged to program in software the decisions about how implement the selected mathematical algorithm. Although math and hardware design are two tough subjects for students, the perception that they get at the end of the course is quite positive.

  9. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer

    National Research Council Canada - National Science Library

    Rosenstein, Barry S

    2005-01-01

    The hypothesis being tested in this project is that a greater proportion of patients who develop radiation-induced subcutaneous late tissue morbidity possess a variant allele in the ATM gene compared...

  10. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer

    National Research Council Canada - National Science Library

    Rosenstein, Barry S

    2006-01-01

    The hypothesis being tested in this project is that a greater proportion of patients who develop radiation-induced subcutaneous late tissue morbidity possess a variant allele in the ATM gene compared...

  11. The Design and Development of a Computerized Tool Support for Conducting Senior Projects in Software Engineering Education

    Science.gov (United States)

    Chen, Chung-Yang; Teng, Kao-Chiuan

    2011-01-01

    This paper presents a computerized tool support, the Meetings-Flow Project Collaboration System (MFS), for designing, directing and sustaining the collaborative teamwork required in senior projects in software engineering (SE) education. Among many schools' SE curricula, senior projects serve as a capstone course that provides comprehensive…

  12. Novel targets for ATM-deficient malignancies

    Science.gov (United States)

    Winkler, Johannes; Hofmann, Kay; Chen, Shuhua

    2014-01-01

    Conventional chemo- and radiotherapies for the treatment of cancer target rapidly dividing cells in both tumor and non-tumor tissues and can exhibit severe cytotoxicity in normal tissue and impair the patient's immune system. Novel targeted strategies aim for higher efficacy and tumor specificity. The role of ATM protein in the DNA damage response is well known and ATM deficiency frequently plays a role in tumorigenesis and development of malignancy. In addition to contributing to disease development, ATM deficiency also renders malignant cells heavily dependent on other pathways that cooperate with the ATM-mediated DNA damage response to ensure tumor cell survival. Disturbing those cooperative pathways by inhibiting critical protein components allows specific targeting of tumors while sparing healthy cells with normal ATM status. We review druggable candidate targets for the treatment of ATM-deficient malignancies and the mechanisms underlying such targeted therapies. PMID:27308314

  13. Functional and nonfunctional testing of ATM networks

    Science.gov (United States)

    Ricardo, Manuel; Ferreira, M. E. P.; Guimaraes, Francisco E.; Mamede, J.; Henriques, M.; da Silva, Jorge A.; Carrapatoso, E.

    1995-02-01

    ATM network will support new multimedia services that will require new protocols, those services and protocols will need different test strategies and tools. In this paper, the concepts of functional and non-functional testers of ATM networks are discussed, a multimedia service and its requirements are presented and finally, a summary description of an ATM network and of the test tool that will be used to validate it are presented.

  14. Synchronous and Asynchronous ATM Multiplexor Properties Comparsion

    OpenAIRE

    Jan Zabka

    2006-01-01

    The article is aimed to ATM multiplexor computer model utilisation. Based on simulation runs we try to review aspects of use a synchronous and asynchronous ATM multiplexors. ATM multiplexor is the input queuing model with three inputs. Synchronous multiplexor works without an input priority. Multiplexor inputs are served periodically. Asynchronous multiplexor model supports several queuing and priority mechanisms. CLR and CTD are basic performance parameters. Input cell flows are genera...

  15. Energy efficiency enhancements for semiconductors, communications, sensors and software achieved in cool silicon cluster project

    Science.gov (United States)

    Ellinger, Frank; Mikolajick, Thomas; Fettweis, Gerhard; Hentschel, Dieter; Kolodinski, Sabine; Warnecke, Helmut; Reppe, Thomas; Tzschoppe, Christoph; Dohl, Jan; Carta, Corrado; Fritsche, David; Tretter, Gregor; Wiatr, Maciej; Detlef Kronholz, Stefan; Mikalo, Ricardo Pablo; Heinrich, Harald; Paulo, Robert; Wolf, Robert; Hübner, Johannes; Waltsgott, Johannes; Meißner, Klaus; Richter, Robert; Michler, Oliver; Bausinger, Markus; Mehlich, Heiko; Hahmann, Martin; Möller, Henning; Wiemer, Maik; Holland, Hans-Jürgen; Gärtner, Roberto; Schubert, Stefan; Richter, Alexander; Strobel, Axel; Fehske, Albrecht; Cech, Sebastian; Aßmann, Uwe; Pawlak, Andreas; Schröter, Michael; Finger, Wolfgang; Schumann, Stefan; Höppner, Sebastian; Walter, Dennis; Eisenreich, Holger; Schüffny, René

    2013-07-01

    An overview about the German cluster project Cool Silicon aiming at increasing the energy efficiency for semiconductors, communications, sensors and software is presented. Examples for achievements are: 1000 times reduced gate leakage in transistors using high-fc (HKMG) materials compared to conventional poly-gate (SiON) devices at the same technology node; 700 V transistors integrated in standard 0.35 μm CMOS; solar cell efficiencies above 19% at cars Contribution to the Topical Issue “International Semiconductor Conference Dresden-Grenoble - ISCDG 2012”, Edited by Gérard Ghibaudo, Francis Balestra and Simon Deleonibus.

  16. Exploring the role of instant messaging in a global software development project

    DEFF Research Database (Denmark)

    Dittrich, Y.; Giuffrida, Rosalba

    2011-01-01

    Communication plays a vital role in software devel- opment projects. Globally distributed teams use a mix of dif- ferent communication channels to get the work done. In this paper, we report on an empirical study of a team distributed across Denmark and India. This paper explores the integration...... documentation. Our analysis provides an indication that IM can play a special role in such socio-technical communication systems: IM acts as a real time glue between different chan- nels. The communication through IM also provides a means to build trust and social relationships with co-workers....

  17. Global Software and IT A Guide to Distributed Development, Projects, and Outsourcing

    CERN Document Server

    Ebert, Christof

    2011-01-01

    Global software engineering, implying both internal and outsourced development, is a fast-growing scenario within industry; the growth rates in some sectors are more than 20% per year. However, half of all offshoring activities are cancelled within the first 2 years, at tremendous unanticipated cost to the organization.   This book will provide a more balanced framework for planning global development, covering topics such as managing people in distributed sites, managing a project across locations, mitigating the risk of offshoring, processes for global development, practical outsourcin

  18. Implementation of virtual LANs over ATM WANs

    Science.gov (United States)

    Braun, Torsten; Maehler, Martin

    1998-09-01

    Virtual LANs (VLANs) allow to interconnect users over campus or wide area networks and gives the users the impression as they would be connected to the same local area network (LAN). The implementation of VLANs is based on ATM Forum's LAN Emulation and LAN/ATM switches providing interconnection of emulated LANs over ATM and the LAN ports to which the user's end systems are attached to. The paper discusses possible implementation architectures and describes advanced features such as ATM short-cuts, QoS, and redundancy concepts.

  19. ATM signaling and 53BP1

    International Nuclear Information System (INIS)

    Zgheib, Omar; Huyen, Yentram; DiTullio, Richard A.; Snyder, Andrew; Venere, Monica; Stavridi, Elena S.; Halazonetis, Thanos D.

    2005-01-01

    The ATM (mutated in Ataxia-Telangiectasia) protein kinase is an important player in signaling the presence of DNA double strand breaks (DSBs) in higher eukaryotes. Recent studies suggest that ATM monitors the presence of DNA DSBs indirectly, through DNA DSB-induced changes in chromatin structure. One of the proteins that sense these chromatin structure changes is 53BP1, a DNA damage checkpoint protein conserved in all eukaryotes and the putative ortholog of the S. cerevisiae RAD9 protein. We review here the mechanisms by which ATM is activated in response to DNA DSBs, as well as key ATM substrates that control cell cycle progression, apoptosis and DNA repair

  20. Integrated Service Provisioning in an Ipv6 over ATM Research Network

    Energy Technology Data Exchange (ETDEWEB)

    Eli Dart; Helen Chen; Jerry Friesen; Jim Brandt; Jim Hutchins; Perry Robertson

    1999-02-01

    During the past few years, the worldwide Internet has grown at a phenomenal rate, which has spurred the proposal of innovative network technologies to support the fast, efficient and low-latency transport of a wide spectrum of multimedia traffic types. Existing network infrastructures have been plagued by their inability to provide for real-time application traffic as well as their general lack of resources and resilience to congestion. This work proposes to address these issues by implementing a prototype high-speed network infrastructure consisting of Internet Protocol Version 6 (IPv6) on top of an Asynchronous Transfer Mode (ATM) transport medium. Since ATM is connection-oriented whereas IP uses a connection-less paradigm, the efficient integration of IPv6 over ATM is especially challenging and has generated much interest in the research community. We propose, in collaboration with an industry partner, to implement IPv6 over ATM using a unique approach that integrates IP over fast A TM hardware while still preserving IP's connection-less paradigm. This is achieved by replacing ATM's control software with IP's routing code and by caching IP's forwarding decisions in ATM's VPI/VCI translation tables. Prototype ''VR'' and distributed-parallel-computing applications will also be developed to exercise the realtime capability of our IPv6 over ATM network.

  1. In-field inspection support software: A status report on the Common Inspection On-site Software Package (CIOSP) project

    International Nuclear Information System (INIS)

    Novatchev, Dimitre; Titov, Pavel; Siradjov, Bakhtiiar; Vlad, Ioan; Xiao Jing

    2001-01-01

    Full text: IAEA has invested much thought and effort into developing software that can assist inspectors during their inspection work. Experience with such applications has been steadily growing and IAEA has recently commissioned a next-generation software package. This kind of software accommodates inspection tasks that can vary substantially in function depending on the type of installation being inspected as well as ensures that the resulting software package has a wide range of usability and can preclude excessive development of plant-specific applications. The Common Inspection On-site Software Package is being developed in the Department of Safeguards to address the limitations of the existing software and to expand its coverage of the inspection process. CIOSP is 'common' in that it is aimed at providing support for as many facilities as possible with the minimum re-configuration. At the same time it has to cater to varying needs of individual facilities, different instrumentation and verification methods used. A component-based approach was taken to successfully tackle the challenges that the development of this software presented. CIOSP consists of the following major components: A framework into which individual plug-ins supporting various inspection activities can integrate at run-time; A central data store containing all facility configuration data and all data collected during inspections; A local data store, which resides on the inspector's computer, where the current inspection's data is stored; A set of services used by all plug-ins (i.e. data transformation, authentication, replication services etc.). This architecture allows for incremental development and extension of the software with plug-ins that support individual inspection activities. The core set of components along with the framework, the Inventory Verification, Book Examination and Records and Reports Comparison plug-ins have been developed. The development of the Short Notice Random

  2. DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity▿ †

    OpenAIRE

    Sun, Yingli; Xu, Ye; Roy, Kanaklata; Price, Brendan D.

    2007-01-01

    The ATM protein kinase is essential for cells to repair and survive genotoxic events. The activation of ATM's kinase activity involves acetylation of ATM by the Tip60 histone acetyltransferase. In this study, systematic mutagenesis of lysine residues was used to identify regulatory ATM acetylation sites. The results identify a single acetylation site at lysine 3016, which is located in the highly conserved C-terminal FATC domain adjacent to the kinase domain. Antibodies specific for acetyl-ly...

  3. Dynamic Staffing and Rescheduling in Software Project Management: A Hybrid Approach.

    Directory of Open Access Journals (Sweden)

    Yujia Ge

    Full Text Available Resource allocation could be influenced by various dynamic elements, such as the skills of engineers and the growth of skills, which requires managers to find an effective and efficient tool to support their staffing decision-making processes. Rescheduling happens commonly and frequently during the project execution. Control options have to be made when new resources are added or tasks are changed. In this paper we propose a software project staffing model considering dynamic elements of staff productivity with a Genetic Algorithm (GA and Hill Climbing (HC based optimizer. Since a newly generated reschedule dramatically different from the initial schedule could cause an obvious shifting cost increase, our rescheduling strategies consider both efficiency and stability. The results of real world case studies and extensive simulation experiments show that our proposed method is effective and could achieve comparable performance to other heuristic algorithms in most cases.

  4. Requirement Volatility, Standardization and Knowledge Integration in Software Projects: An Empirical Analysis on Outsourced IS Development Projects

    Directory of Open Access Journals (Sweden)

    Rajesri Govindaraju

    2015-08-01

    Full Text Available Information systems development (ISD projects are highly complex, with different groups of people having  to collaborate and exchange their knowledge. Considering the intensity of knowledge exchange that takes place in outsourced ISD projects, in this study a conceptual model was developed, aiming to examine the influence of four antecedents, i.e. standardization, requirement volatility, internal integration, and external integration, on two dependent variables, i.e. process performance and product performance. Data  were collected from 46 software companies in four big cities in Indonesia. The collected data were examined to verify the proposed theoretical model using the partial least square structural equation modeling (PLS-SEM technique. The results show that process performance is significantly influenced by internal integration and standardization, while product performance is  significantly influenced by external integration and  requirement volatility. This study contributes  to a better understanding of how knowledge integration can be managed in outsourced ISD projects in view of increasing their success.

  5. Functional Characterization of ATM Kinase Using Acetylation-Specific Antibodies.

    Science.gov (United States)

    Sun, Yingli; Du, Fengxia

    2017-01-01

    The activation of ATM is critical in the DNA double strand breaks repair pathway. Acetylation of ATM by Tip60 histone acetyltransferase (HAT) plays a key role in the activation of ATM kinase activity in response to DNA damage. ATM forms a stable complex with Tip60 through the FATC domain of ATM. Tip60 acetylates lysine3016 of ATM, and this acetylation induces the activation of ATM. Several techniques are included in the study of ATM acetylation by Tip60, such as in vitro kinase assay, systematic mutagenesis, western blots. Here, we describe how to study the acetylation of ATM using acetylation-specific antibodies.

  6. A survey of quality assurance practices in biomedical open source software projects.

    Science.gov (United States)

    Koru, Günes; El Emam, Khaled; Neisa, Angelica; Umarji, Medha

    2007-05-07

    Open source (OS) software is continuously gaining recognition and use in the biomedical domain, for example, in health informatics and bioinformatics. Given the mission critical nature of applications in this domain and their potential impact on patient safety, it is important to understand to what degree and how effectively biomedical OS developers perform standard quality assurance (QA) activities such as peer reviews and testing. This would allow the users of biomedical OS software to better understand the quality risks, if any, and the developers to identify process improvement opportunities to produce higher quality software. A survey of developers working on biomedical OS projects was conducted to examine the QA activities that are performed. We took a descriptive approach to summarize the implementation of QA activities and then examined some of the factors that may be related to the implementation of such practices. Our descriptive results show that 63% (95% CI, 54-72) of projects did not include peer reviews in their development process, while 82% (95% CI, 75-89) did include testing. Approximately 74% (95% CI, 67-81) of developers did not have a background in computing, 80% (95% CI, 74-87) were paid for their contributions to the project, and 52% (95% CI, 43-60) had PhDs. A multivariate logistic regression model to predict the implementation of peer reviews was not significant (likelihood ratio test = 16.86, 9 df, P = .051) and neither was a model to predict the implementation of testing (likelihood ratio test = 3.34, 9 df, P = .95). Less attention is paid to peer review than testing. However, the former is a complementary, and necessary, QA practice rather than an alternative. Therefore, one can argue that there are quality risks, at least at this point in time, in transitioning biomedical OS software into any critical settings that may have operational, financial, or safety implications. Developers of biomedical OS applications should invest more effort

  7. Software Configuration Management Plan for the K West Basin Integrated Water Treatment System (IWTS) - Project A.9

    International Nuclear Information System (INIS)

    GREEN, J.W.

    2000-01-01

    This document provides a configuration control plan for the software associated with the operation and control of the Integrated Water Treatment System (IWTS). It establishes requirements for ensuring configuration item identification, configuration control, configuration status accounting, defect reporting and resolution of computer software. It is written to comply with HNF-SD-SNF-CM-001, Spent Nuclear Fuel Configuration Management Plan (Forehand 1998) and HNF-PRO-309 Computer Software Quality Assurance Requirements, and applicable sections of administrative procedure CM-6-037-00, SNF Project Process Automation Software and Equipment

  8. The ALPS project release 2.0: open source software for strongly correlated systems

    International Nuclear Information System (INIS)

    Bauer, B; Gamper, L; Gukelberger, J; Hehn, A; Isakov, S V; Ma, P N; Mates, P; Carr, L D; Evertz, H G; Feiguin, A; Freire, J; Koop, D; Fuchs, S; Gull, E; Guertler, S; Igarashi, R; Matsuo, H; Parcollet, O; Pawłowski, G; Picon, J D

    2011-01-01

    We present release 2.0 of the ALPS (Algorithms and Libraries for Physics Simulations) project, an open source software project to develop libraries and application programs for the simulation of strongly correlated quantum lattice models such as quantum magnets, lattice bosons, and strongly correlated fermion systems. The code development is centered on common XML and HDF5 data formats, libraries to simplify and speed up code development, common evaluation and plotting tools, and simulation programs. The programs enable non-experts to start carrying out serial or parallel numerical simulations by providing basic implementations of the important algorithms for quantum lattice models: classical and quantum Monte Carlo (QMC) using non-local updates, extended ensemble simulations, exact and full diagonalization (ED), the density matrix renormalization group (DMRG) both in a static version and a dynamic time-evolving block decimation (TEBD) code, and quantum Monte Carlo solvers for dynamical mean field theory (DMFT). The ALPS libraries provide a powerful framework for programmers to develop their own applications, which, for instance, greatly simplify the steps of porting a serial code onto a parallel, distributed memory machine. Major changes in release 2.0 include the use of HDF5 for binary data, evaluation tools in Python, support for the Windows operating system, the use of CMake as build system and binary installation packages for Mac OS X and Windows, and integration with the VisTrails workflow provenance tool. The software is available from our web server at http://alps.comp-phys.org/

  9. Status report of the SRT radiotelescope control software: the DISCOS project

    Science.gov (United States)

    Orlati, A.; Bartolini, M.; Buttu, M.; Fara, A.; Migoni, C.; Poppi, S.; Righini, S.

    2016-08-01

    The Sardinia Radio Telescope (SRT) is a 64-m fully-steerable radio telescope. It is provided with an active surface to correct for gravitational deformations, allowing observations from 300 MHz to 100 GHz. At present, three receivers are available: a coaxial LP-band receiver (305-410 MHz and 1.5-1.8 GHz), a C-band receiver (5.7-7.7 GHz) and a 7-feed K-band receiver (18-26.5 GHz). Several back-ends are also available in order to perform the different data acquisition and analysis procedures requested by scientific projects. The design and development of the SRT control software started in 2004, and now belongs to a wider project called DISCOS (Development of the Italian Single-dish COntrol System), which provides a common infrastructure to the three Italian radio telescopes (Medicina, Noto and SRT dishes). DISCOS is based on the Alma Common Software (ACS) framework, and currently consists of more than 500k lines of code. It is organized in a common core and three specific product lines, one for each telescope. Recent developments, carried out after the conclusion of the technical commissioning of the instrument (October 2013), consisted in the addition of several new features in many parts of the observing pipeline, spanning from the motion control to the digital back-ends for data acquisition and data formatting; we brie y describe such improvements. More importantly, in the last two years we have supported the astronomical validation of the SRT radio telescope, leading to the opening of the first public call for proposals in late 2015. During this period, while assisting both the engineering and the scientific staff, we massively employed the control software and were able to test all of its features: in this process we received our first feedback from the users and we could verify how the system performed in a real-life scenario, drawing the first conclusions about the overall system stability and performance. We examine how the system behaves in terms of network

  10. ATM: Restructing Learning for Deaf Students.

    Science.gov (United States)

    Keefe, Barbara; Stockford, David

    Governor Baxter School for the Deaf is one of six Maine pilot sites chosen by NYNEX to showcase asynchronous transfer mode (ATM) technology. ATM is a network connection that allows high bandwidth transmission of data, voice, and video. Its high speed capability allows for high quality two-way full-motion video, which is especially beneficial to a…

  11. The State of Open Source Electronic Health Record Projects: A Software Anthropology Study.

    Science.gov (United States)

    Alsaffar, Mona; Yellowlees, Peter; Odor, Alberto; Hogarth, Michael

    2017-02-24

    Electronic health records (EHR) are a key tool in managing and storing patients' information. Currently, there are over 50 open source EHR systems available. Functionality and usability are important factors for determining the success of any system. These factors are often a direct reflection of the domain knowledge and developers' motivations. However, few published studies have focused on the characteristics of free and open source software (F/OSS) EHR systems and none to date have discussed the motivation, knowledge background, and demographic characteristics of the developers involved in open source EHR projects. This study analyzed the characteristics of prevailing F/OSS EHR systems and aimed to provide an understanding of the motivation, knowledge background, and characteristics of the developers. This study identified F/OSS EHR projects on SourceForge and other websites from May to July 2014. Projects were classified and characterized by license type, downloads, programming languages, spoken languages, project age, development status, supporting materials, top downloads by country, and whether they were "certified" EHRs. Health care F/OSS developers were also surveyed using an online survey. At the time of the assessment, we uncovered 54 open source EHR projects, but only four of them had been successfully certified under the Office of the National Coordinator for Health Information Technology (ONC Health IT) Certification Program. In the majority of cases, the open source EHR software was downloaded by users in the United States (64.07%, 148,666/232,034), underscoring that there is a significant interest in EHR open source applications in the United States. A survey of EHR open source developers was conducted and a total of 103 developers responded to the online questionnaire. The majority of EHR F/OSS developers (65.3%, 66/101) are participating in F/OSS projects as part of a paid activity and only 25.7% (26/101) of EHR F/OSS developers are, or have been

  12. Satellite ATM Networks: Architectures and Guidelines Developed

    Science.gov (United States)

    vonDeak, Thomas C.; Yegendu, Ferit

    1999-01-01

    An important element of satellite-supported asynchronous transfer mode (ATM) networking will involve support for the routing and rerouting of active connections. Work published under the auspices of the Telecommunications Industry Association (http://www.tiaonline.org), describes basic architectures and routing protocol issues for satellite ATM (SATATM) networks. The architectures and issues identified will serve as a basis for further development of technical specifications for these SATATM networks. Three ATM network architectures for bent pipe satellites and three ATM network architectures for satellites with onboard ATM switches were developed. The architectures differ from one another in terms of required level of mobility, supported data rates, supported terrestrial interfaces, and onboard processing and switching requirements. The documentation addresses low-, middle-, and geosynchronous-Earth-orbit satellite configurations. The satellite environment may require real-time routing to support the mobility of end devices and nodes of the ATM network itself. This requires the network to be able to reroute active circuits in real time. In addition to supporting mobility, rerouting can also be used to (1) optimize network routing, (2) respond to changing quality-of-service requirements, and (3) provide a fault tolerance mechanism. Traffic management and control functions are necessary in ATM to ensure that the quality-of-service requirements associated with each connection are not violated and also to provide flow and congestion control functions. Functions related to traffic management were identified and described. Most of these traffic management functions will be supported by on-ground ATM switches, but in a hybrid terrestrial-satellite ATM network, some of the traffic management functions may have to be supported by the onboard satellite ATM switch. Future work is planned to examine the tradeoffs of placing traffic management functions onboard a satellite as

  13. Management of Globally Distributed Software Development Projects in Multiple-Vendor Constellations

    Science.gov (United States)

    Schott, Katharina; Beck, Roman; Gregory, Robert Wayne

    Global information systems development outsourcing is an apparent trend that is expected to continue in the foreseeable future. Thereby, IS-related services are not only increasingly provided from different geographical sites simultaneously but beyond that from multiple service providers based in different countries. The purpose of this paper is to understand how the involvement of multiple service providers affects the management of the globally distributed information systems development projects. As research on this topic is scarce, we applied an exploratory in-depth single-case study design as research approach. The case we analyzed comprises a global software development outsourcing project initiated by a German bank together with several globally distributed vendors. For data collection and data analysis we have adopted techniques suggested by the grounded theory method. Whereas the extant literature points out the increased management overhead associated with multi-sourcing, the analysis of our case suggests that the required effort for managing global outsourcing projects with multiple vendors depends among other things on the maturation level of the cooperation within the vendor portfolio. Furthermore, our data indicate that this interplay maturity is positively impacted through knowledge about the client that has been derived based on already existing client-vendor relationships. The paper concludes by offering theoretical and practical implications.

  14. ATM Security via "Stargate" Solution

    National Research Council Canada - National Science Library

    Hensley, Katrina

    1999-01-01

    .... The authenticating device, Stargate, utilizes a high speed, low level authentication protocol that offers the low cost, flexibility, and extensibility of software, while still capable of yielding...

  15. Development and Engineering Design in Support of "Rover Ranch": A K-12 Outreach Software Project

    Science.gov (United States)

    Pascali, Raresh

    2003-01-01

    A continuation of the initial development started in the summer of 1999, the body of work performed in support of 'ROVer Ranch' Project during the present fellowship dealt with the concrete concept implementation and resolution of the related issues. The original work performed last summer focused on the initial examination and articulation of the concept treatment strategy, audience and market analysis for the learning technologies software. The presented work focused on finalizing the set of parts to be made available for building an AERCam Sprint type robot and on defining, testing and implementing process necessary to convert the design engineering files to VRML files. Through reverse engineering, an initial set of mission critical systems was designed for beta testing in schools. The files were created in ProEngineer, exported to VRML 1.0 and converted to VRML 97 (VRML 2.0) for final integration in the software. Attributes for each part were assigned using an in-house developed JAVA based program. The final set of attributes for each system, their mutual interaction and the identification of the relevant ones to be tracked, still remain to be decided.

  16. R PROJECT: SU APLICACIÓN COMO SOFTWARE LIBRE PARA ANÁLISIS EN COMPONENTES PRINCIPALES

    Directory of Open Access Journals (Sweden)

    Fabricio Bolaños Guerrero

    2011-01-01

    Full Text Available Este artículo es producto de un proyecto de investigación realizado en colaboración con profesores de la Escuela de Matemáticas de la Universidad de Costa Rica (UCR, para dar a conocer una opción de software estadístico llamado R Project. Con este paquete es posible hacer Análisis en Componentes Principales (ACP y representar los resultados usando el Plano Principal y el Círculo de Correlaciones, como herramientas para poder realizar una mejor interpretación de los datos de la tabla (individuos y variables. El software R es de distribución libre, su implementación es sencilla y no requiere de mayores recursos informáticos. Dentro de sus diversas aplicaciones está el ACP, que es una herramienta que se utiliza para la interpretación de la información presentada en una tabla de datos cuantitativos; por lo tanto, las personas investigadoras de diferentes áreas tienen una opción económica y sencilla para realizar Análisis de Datos. Se llevan a cabo dos ejemplos de ACP, donde se muestra un posible uso de la herramienta y se dan las instrucciones sobre cómo realizarlo paso a paso.

  17. Project maturity evaluation model for SMEs from the software development sub-sector

    Directory of Open Access Journals (Sweden)

    ÁLVARO JULIO CUADROS LÓPEZ

    Full Text Available The purpose of the paper is to present a project management maturity model for SMEs oriented to software development. The proposal is based on CMMI capability maturity model, and the SCAMPI evaluation method. The proposal includes a quantitative satisfaction scale, redundant evidence assessment, and multiple criteria for selecting experts. The proposal was validated with a case study carried out in a medium-sized company from the Information and Communications Technology sector. The model concluded that the company did not reach maturity level 2; however it showed that 92% of the processes from maturity level 2 and 77% of the total process had already been implemented, which allows the company to adopt a specific orientation for its improvement efforts.

  18. ProjectQ: an open source software framework for quantum computing

    Directory of Open Access Journals (Sweden)

    Damian S. Steiger

    2018-01-01

    Full Text Available We introduce ProjectQ, an open source software effort for quantum computing. The first release features a compiler framework capable of targeting various types of hardware, a high-performance simulator with emulation capabilities, and compiler plug-ins for circuit drawing and resource estimation. We introduce our Python-embedded domain-specific language, present the features, and provide example implementations for quantum algorithms. The framework allows testing of quantum algorithms through simulation and enables running them on actual quantum hardware using a back-end connecting to the IBM Quantum Experience cloud service. Through extension mechanisms, users can provide back-ends to further quantum hardware, and scientists working on quantum compilation can provide plug-ins for additional compilation, optimization, gate synthesis, and layout strategies.

  19. Sustainability in Open Source Software Commons: Lessons Learned from an Empirical Study of SourceForge Projects

    OpenAIRE

    Charles M. Schweik

    2013-01-01

    In this article, we summarize a five-year US National Science Foundation funded study designed to investigate the factors that lead some open source projects to ongoing collaborative success while many others become abandoned. Our primary interest was to conduct a study that was closely representative of the population of open source software projects in the world, rather than focus on the more-often studied, high-profile successful cases. After building a large database of projects (n=174,33...

  20. Enhanced ATM Security using Biometric Authentication and Wavelet Based AES

    Directory of Open Access Journals (Sweden)

    Sreedharan Ajish

    2016-01-01

    Full Text Available The traditional ATM terminal customer recognition systems rely only on bank cards, passwords and such identity verification methods are not perfect and functions are too single. Biometrics-based authentication offers several advantages over other authentication methods, there has been a significant surge in the use of biometrics for user authentication in recent years. This paper presents a highly secured ATM banking system using biometric authentication and wavelet based Advanced Encryption Standard (AES algorithm. Two levels of security are provided in this proposed design. Firstly we consider the security level at the client side by providing biometric authentication scheme along with a password of 4-digit long. Biometric authentication is achieved by considering the fingerprint image of the client. Secondly we ensure a secured communication link between the client machine to the bank server using an optimized energy efficient and wavelet based AES processor. The fingerprint image is the data for encryption process and 4-digit long password is the symmetric key for the encryption process. The performance of ATM machine depends on ultra-high-speed encryption, very low power consumption, and algorithmic integrity. To get a low power consuming and ultra-high speed encryption at the ATM machine, an optimized and wavelet based AES algorithm is proposed. In this system biometric and cryptography techniques are used together for personal identity authentication to improve the security level. The design of the wavelet based AES processor is simulated and the design of the energy efficient AES processor is simulated in Quartus-II software. Simulation results ensure its proper functionality. A comparison among other research works proves its superiority.

  1. Open source projects as incubators of innovation: From niche phenomenon to integral part of the software industry

    OpenAIRE

    Schrape, Jan-Felix

    2017-01-01

    Over the last 20 years, open source development has become an integral part of the software industry and a key component of the innovation strategies of all major IT providers. Against this backdrop, this paper seeks to develop a systematic overview of open source communities and their socio-economic contexts. I begin with a reconstruction of the genesis of open source software projects and their changing relation- ships to established IT companies. This is followed by the identification of f...

  2. Projeto Seis Sigma para a implementação de software de programação Six Sigma project for scheduling software implementation

    Directory of Open Access Journals (Sweden)

    Rogério Cerávolo Calia

    2005-12-01

    Full Text Available O artigo visa analisar a eficácia organizacional da metodologia Seis Sigma na gestão de projetos para a redução de atrasos e redução de estoques na manufatura, por meio da implementação de um software com algoritmos da Teoria das Restrições. Inicialmente, é apresentada uma revisão bibliográfica sobre a gestão de projetos na perspectiva da gestão da mudança organizacional nos processos de negócios. Em seguida, são revistos os conceitos sobre a metodologia Seis Sigma para a gestão de projetos e sobre os algoritmos da Teoria das Restrições. Então, são descritos os estudos de caso em dois projetos de implementação do software da Teoria das Restrições, sendo que apenas uma das implementações utilizou-se da metodologia Seis Sigma para a gestão do projeto. Na análise dos resultados, busca-se compreender os motivos de o projeto com a metodologia Seis Sigma ter reduzido inventário três vezes mais rápido do que o projeto sem o Seis Sigma.The article aims to analyze the organizational effectiveness of the Six Sigma methodology for project management to reduce delays and to reduce inventory in manufacture, by the implementation of software with Theory of Constraints algorithms. Initially, the article presents a bibliographic revision on project management and its impact on the organizational change management for improving business processes. Then, the article revises the concepts about the Six Sigma methodology for project management and about the Theory of Constraints algorithms. It follows, the case studies descriptions on two implementation projects of the Theory of Constraints software, in which only one of these implementations adopted the Six Sigma methodology in the project management. In the results analyzes, the article discusses the reasons why the project with the Six Sigma methodology was three times faster than the other project.

  3. A Software Engineering Paradigm for Quick-turnaround Earth Science Data Projects

    Science.gov (United States)

    Moore, K.

    2016-12-01

    As is generally the case with applied sciences professional and educational programs, the participants of such programs can come from a variety of technical backgrounds. In the NASA DEVELOP National Program, the participants constitute an interdisciplinary set of backgrounds, with varying levels of experience with computer programming. DEVELOP makes use of geographically explicit data sets, and it is necessary to use geographic information systems and geospatial image processing environments. As data sets cover longer time spans and include more complex sets of parameters, automation is becoming an increasingly prevalent feature. Though platforms such as ArcGIS, ERDAS Imagine, and ENVI facilitate the batch-processing of geospatial imagery, these environments are naturally constricting to the user in that they limit him or her to the tools that are available. Users must then turn to "homemade" scripting in more traditional programming languages such as Python, JavaScript, or R, to automate workflows. However, in the context of quick-turnaround projects like those in DEVELOP, the programming learning curve may be prohibitively steep. In this work, we consider how to best design a software development paradigm that addresses two major constants: an arbitrarily experienced programmer and quick-turnaround project timelines.

  4. OPTiM: Optical projection tomography integrated microscope using open-source hardware and software.

    Science.gov (United States)

    Watson, Thomas; Andrews, Natalie; Davis, Samuel; Bugeon, Laurence; Dallman, Margaret D; McGinty, James

    2017-01-01

    We describe the implementation of an OPT plate to perform optical projection tomography (OPT) on a commercial wide-field inverted microscope, using our open-source hardware and software. The OPT plate includes a tilt adjustment for alignment and a stepper motor for sample rotation as required by standard projection tomography. Depending on magnification requirements, three methods of performing OPT are detailed using this adaptor plate: a conventional direct OPT method requiring only the addition of a limiting aperture behind the objective lens; an external optical-relay method allowing conventional OPT to be performed at magnifications >4x; a remote focal scanning and region-of-interest method for improved spatial resolution OPT (up to ~1.6 μm). All three methods use the microscope's existing incoherent light source (i.e. arc-lamp) and all of its inherent functionality is maintained for day-to-day use. OPT acquisitions are performed on in vivo zebrafish embryos to demonstrate the implementations' viability.

  5. Hyper-Spectral Communications, Networking and ATM as Foundation for Safe and Efficient Future Flight: Transcending Aviation Operational Limitations with Diverse and Secure Multi-Band, Multi-Mode, and mmWave Wireless Links: Project Overview, Aviation Communications and New Signaling

    Science.gov (United States)

    Matolak, David W.

    2017-01-01

    NASA's Aeronautics Research Mission Directorate (ARMD) has recently solicited proposals and awarded funds for research and development to achieve and exceed the goals envisioned in the ARMD Strategic Implementation Plan (SIP). The Hyper-Spectral Communications and Networking for Air Traffic Management (ATM) (HSCNA) project is the only University Leadership Initiative (ULI) program to address communications and networking (and to a degree, navigation and surveillance). This paper will provide an overview of the HSCNA project, and specifically describe two of the project's technical challenges: comprehensive aviation communications and networking assessment, and proposed multi-band and multimode communications and networking. The primary goals will be described, as will be research and development aimed to achieve and exceed these goals. Some example initial results are also provided.

  6. Guidelines for the verification and validation of expert system software and conventional software: Project summary. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Mirsky, S.M.; Hayes, J.E.; Miller, L.A. [Science Applications International Corp., McLean, VA (United States)

    1995-03-01

    This eight-volume report presents guidelines for performing verification and validation (V&V) on Artificial Intelligence (Al) systems with nuclear applications. The guidelines have much broader application than just expert systems; they are also applicable to object-oriented programming systems, rule-based systems, frame-based systems, model-based systems, neural nets, genetic algorithms, and conventional software systems. This is because many of the components of AI systems are implemented in conventional procedural programming languages, so there is no real distinction. The report examines the state of the art in verifying and validating expert systems. V&V methods traditionally applied to conventional software systems are evaluated for their applicability to expert systems. One hundred fifty-three conventional techniques are identified and evaluated. These methods are found to be useful for at least some of the components of expert systems, frame-based systems, and object-oriented systems. A taxonomy of 52 defect types and their delectability by the 153 methods is presented. With specific regard to expert systems, conventional V&V methods were found to apply well to all the components of the expert system with the exception of the knowledge base. The knowledge base requires extension of the existing methods. Several innovative static verification and validation methods for expert systems have been identified and are described here, including a method for checking the knowledge base {open_quotes}semantics{close_quotes} and a method for generating validation scenarios. Evaluation of some of these methods was performed both analytically and experimentally. A V&V methodology for expert systems is presented based on three factors: (1) a system`s judged need for V&V (based in turn on its complexity and degree of required integrity); (2) the life-cycle phase; and (3) the system component being tested.

  7. Guidelines for the verification and validation of expert system software and conventional software. Volume 1: Project summary. Final report

    International Nuclear Information System (INIS)

    Miller, L.A.; Hayes, J.E.; Mirsky, S.M.

    1995-05-01

    This eight-volume report presents guidelines for performing verification and validation (V ampersand V) on Artificial Intelligence (AI) systems with nuclear applications. The guidelines have much broader application than just expert systems; they are also applicable to object-oriented programming systems, rule-based systems, frame-based systems, model-based systems, neural nets, genetic algorithms, and conventional software systems. This is because many of the components of AI systems are implemented in conventional procedural programming languages, so there is no real distinction. The report examines the state of the art in verifying and validating expert systems. V ampersand V methods traditionally applied to conventional software systems are evaluated for their applicability to expert systems. One hundred fifty-three conventional techniques are identified and evaluated. These methods are found to be useful for at least some of the components of expert systems, frame-based systems, and object-oriented systems. A taxonomy of 52 defect types and their delectability by the 153 methods is presented. With specific regard to expert systems, conventional V ampersand V methods were found to apply well to all the components of the expert system with the exception of the knowledge base. The knowledge base requires extension of the existing methods. Several innovative static verification and validation methods for expert systems have been identified and are described here, including a method for checking the knowledge base open-quotes semanticsclose quotes and a method for generating validation scenarios. Evaluation of some of these methods was performed both analytically and experimentally

  8. Guidelines for the verification and validation of expert system software and conventional software: Project summary. Volume 1

    International Nuclear Information System (INIS)

    Mirsky, S.M.; Hayes, J.E.; Miller, L.A.

    1995-03-01

    This eight-volume report presents guidelines for performing verification and validation (V ampersand V) on Artificial Intelligence (Al) systems with nuclear applications. The guidelines have much broader application than just expert systems; they are also applicable to object-oriented programming systems, rule-based systems, frame-based systems, model-based systems, neural nets, genetic algorithms, and conventional software systems. This is because many of the components of AI systems are implemented in conventional procedural programming languages, so there is no real distinction. The report examines the state of the art in verifying and validating expert systems. V ampersand V methods traditionally applied to conventional software systems are evaluated for their applicability to expert systems. One hundred fifty-three conventional techniques are identified and evaluated. These methods are found to be useful for at least some of the components of expert systems, frame-based systems, and object-oriented systems. A taxonomy of 52 defect types and their delectability by the 153 methods is presented. With specific regard to expert systems, conventional V ampersand V methods were found to apply well to all the components of the expert system with the exception of the knowledge base. The knowledge base requires extension of the existing methods. Several innovative static verification and validation methods for expert systems have been identified and are described here, including a method for checking the knowledge base open-quotes semanticsclose quotes and a method for generating validation scenarios. Evaluation of some of these methods was performed both analytically and experimentally. A V ampersand V methodology for expert systems is presented based on three factors: (1) a system's judged need for V ampersand V (based in turn on its complexity and degree of required integrity); (2) the life-cycle phase; and (3) the system component being tested

  9. Software proyecto y presupuesto de una investigación en salud A software project and estimate of a health research

    Directory of Open Access Journals (Sweden)

    Manuel Piloto Morejón

    2011-03-01

    Full Text Available Introducción: La confección de un proyecto de investigación es una tarea difícil por la diversidad de los conocimientos básicos de Metodología de la Investigación, Bioestadística y Economía, necesarios para enfrentar las diferentes secciones del mismo. Objetivo: garantizar la confección adecuada de los proyectos de investigación de cualquier nivel y la confección uniforme y facilitada del cálculo económico (presupuesto para todos los proyectos de investigación de la provincia. Material y métodos: se confeccionó un software que facilita a los investigadores la confección de un proyecto de investigación, tomando como base la guía oficial de un proyecto ramal del CITMA (según establece la Resolución Ministerial 110/2009 y los numerosos cálculos matemáticos del presupuesto de un proyecto de investigación de forma automatizada a partir de los datos económicos primarios. Resultados: el software no necesita instalación. Es un instrumento útil para cualquier investigador ya que resulta fácil de manejar. Concentra lo elemental y sencillo mediante la existencia del Manual de Usuario. Es aplicable y de pequeño tamaño (Kb, fiable y eficiente. Tiene facilidad de uso y de mantenimiento y beneficios sociales, tecnológicos, científicos y económicos. Este software es utilizado por el 100% de los investigadores de la provincia en los proyectos ramales, territoriales, institucionales, de Trabajos de Terminación de la Especialidad y Trabajos de Terminación de las Maestrías.Introduction: to prepare a project for scientific research is a difficult task due to the diversity of basic knowledge about Methodology of Scientific Research, Biostatistics and Economy which are necessary to face up the different sections of the project. Objective: to guarantee the suitable groundwork of research projects at any level as well as the uniform preparation for economic calculation (estimate of the whole research projects of the province

  10. Activation of ATM by DNA Damaging Agents

    National Research Council Canada - National Science Library

    Kurz, Ebba U; Lees-Miller, Susan P

    2004-01-01

    Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase that acts as a master switch controlling the cell cycle in response to ionizing radiation-induced DNA double-strand breaks (DSBs...

  11. Flow enforcement algorithms for ATM networks

    DEFF Research Database (Denmark)

    Dittmann, Lars; Jacobsen, Søren B.; Moth, Klaus

    1991-01-01

    Four measurement algorithms for flow enforcement in asynchronous transfer mode (ATM) networks are presented. The algorithms are the leaky bucket, the rectangular sliding window, the triangular sliding window, and the exponentially weighted moving average. A comparison, based partly on teletraffic...

  12. Activation of ATM by DNA Damaging Agents

    National Research Council Canada - National Science Library

    Kurz, Ebba U; Lees-Miller, Susan P

    2005-01-01

    Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase that acts as a master switch controlling the cell cycle in response to ionizing radiation-induced DNA double-strand breaks (DSBs...

  13. A perspective on how ATM lost Control

    NARCIS (Netherlands)

    Crosby, S.; Rooney, S.; Isaacs, R.; Bos, H.J.

    2002-01-01

    Contrary to the initial high expectations, ATM failed to become the universal network technology covering all services and running from the desktop to the back-bone. This paper tries to identify the technological problems that contributed to this failure.

  14. A survey of IP over ATM architectures

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H.; Tsang, R.; Brandt, J.; Hutchins, J.

    1997-07-01

    Over the past decade, the Internet has burgeoned into a worldwide information highway consisting of approximately 5 million hosts on over 45,000 interconnected networks. This unprecedented growth, together with the introduction of multimedia workstations, has spurred the development of innovative applications that require high speed, low latency, and real-time transport. Today`s Internet can neither scale in its bandwidth nor guarantee the Quality of Services (QoS) necessary to meet these performance requirements. Many network researchers propose to use the Asynchronous Transfer Mode (ATM) technology as the underlying infrastructure for the next generation of workgroup, campus, and enterprise IP networks. Since ATM is significantly different from today`s legacy network technologies, efficient implementation of IP over ATM is especially challenging. This tutorial paper covers several existing proposals that integrate IP over ATM.

  15. ATM Card Cloning and Ethical Considerations.

    Science.gov (United States)

    Kaur, Paramjit; Krishan, Kewal; Sharma, Suresh K; Kanchan, Tanuj

    2018-05-01

    With the advent of modern technology, the way society handles and performs monetary transactions has changed tremendously. The world is moving swiftly towards the digital arena. The use of Automated Teller Machine (ATM) cards (credit and debit) has led to a "cash-less society" and has fostered digital payments and purchases. In addition to this, the trust and reliance of the society upon these small pieces of plastic, having numbers engraved upon them, has increased immensely over the last two decades. In the past few years, the number of ATM fraud cases has increased exponentially. With the money of the people shifting towards the digital platform, ATM skimming has become a problem that has eventually led to a global outcry. The present review discusses the serious repercussions of ATM card cloning and the associated privacy, ethical and legal concerns. The preventive measures which need to be taken and adopted by the government authorities to mitigate the problem have also been discussed.

  16. The MEDA Project: Developing Evaluation Competence in the Training Software Domain.

    Science.gov (United States)

    Machell, Joan; Saunders, Murray

    1992-01-01

    The MEDA (Methodologie d'Evaluation des Didacticiels pour les Adultes) tool is a generic instrument to evaluate training courseware. It was developed for software designers to improve products, for instructors to select appropriate courseware, and for distributors and consultants to match software to client needs. Describes software evaluation…

  17. Studies of ATM for ATLAS high-level triggers

    CERN Document Server

    Bystrický, J; Huet, M; Le Dû, P; Mandjavidze, I D

    2001-01-01

    This paper presents some of the conclusions of our studies on asynchronous transfer mode (ATM) and fast Ethernet in the ATLAS level-2 trigger pilot project. We describe the general concept and principles of our data-collection and event-building scheme that could be transposed to various experiments in high-energy and nuclear physics. To validate the approach in view of ATLAS high-level triggers, we assembled a testbed composed of up to 48 computers linked by a 7.5-Gbit/s ATM switch. This modular switch is used as a single entity or is split into several smaller interconnected switches. This allows study of how to construct a large network from smaller units. Alternatively, the ATM network can be replaced by fast Ethernet. We detail the operation of the system and present series of performance measurements made with event-building traffic pattern. We extrapolate these results to show how today's commercial networking components could be used to build a 1000-port network adequate for ATLAS needs. Lastly, we li...

  18. Application of Open Source Software by the Lunar Mapping and Modeling Project

    Science.gov (United States)

    Ramirez, P.; Goodale, C. E.; Bui, B.; Chang, G.; Kim, R. M.; Law, E.; Malhotra, S.; Rodriguez, L.; Sadaqathullah, S.; Mattmann, C. A.; Crichton, D. J.

    2011-12-01

    The Lunar Mapping and Modeling Project (LMMP), led by the Marshall Space Flight center (MSFC), is responsible for the development of an information system to support lunar exploration, decision analysis, and release of lunar data to the public. The data available through the lunar portal is predominantly derived from present lunar missions (e.g., the Lunar Reconnaissance Orbiter (LRO)) and from historical missions (e.g., Apollo). This project has created a gold source of data, models, and tools for lunar explorers to exercise and incorporate into their activities. At Jet Propulsion Laboratory (JPL), we focused on engineering and building the infrastructure to support cataloging, archiving, accessing, and delivery of lunar data. We decided to use a RESTful service-oriented architecture to enable us to abstract from the underlying technology choices and focus on interfaces to be used internally and externally. This decision allowed us to leverage several open source software components and integrate them by either writing a thin REST service layer or relying on the API they provided; the approach chosen was dependent on the targeted consumer of a given interface. We will discuss our varying experience using open source products; namely Apache OODT, Oracle Berkley DB XML, Apache Solr, and Oracle OpenSSO (now named OpenAM). Apache OODT, developed at NASA's Jet Propulsion Laboratory and recently migrated over to Apache, provided the means for ingestion and cataloguing of products within the infrastructure. Its usage was based upon team experience with the project and past benefit received on other projects internal and external to JPL. Berkeley DB XML, distributed by Oracle for both commercial and open source use, was the storage technology chosen for our metadata. This decision was in part based on our use Federal Geographic Data Committee (FGDC) Metadata, which is expressed in XML, and the desire to keep it in its native form and exploit other technologies built on

  19. ATM Coastal Topography-Texas, 2001: UTM Zone 14

    Science.gov (United States)

    Klipp, Emily S.; Nayegandhi, Amar; Brock, John C.; Sallenger, A.H.; Bonisteel, Jamie M.; Yates, Xan; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived first-surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of a portion of the Texas coastline within UTM zone 14, acquired October 12-13, 2001. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative scanning lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is used

  20. ATM Coastal Topography-Florida 2001: Eastern Panhandle

    Science.gov (United States)

    Yates, Xan; Nayegandhi, Amar; Brock, John C.; Sallenger, A.H.; Bonisteel, Jamie M.; Klipp, Emily S.; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of Lidar-derived first surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the eastern Florida panhandle coastline, acquired October 2, 2001. The datasets are made available for use as a management tool to research scientists and natural resource managers. An innovative scanning Lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning Lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of Lidar data in an interactive or batch mode. Modules for presurvey flight line definition, flight path plotting, Lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is routinely used to create

  1. ATM Coastal Topography-Texas, 2001: UTM Zone 15

    Science.gov (United States)

    Klipp, Emily S.; Nayegandhi, Amar; Brock, John C.; Sallenger, A.H.; Bonisteel, Jamie M.; Yates, Xan; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived first-surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of a portion of the Texas coastline within UTM zone 15, from Matagorda Peninsula to Galveston Island, acquired October 12-13, 2001. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative scanning lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant

  2. ATM Coastal Topography-Florida 2001: Western Panhandle

    Science.gov (United States)

    Yates, Xan; Nayegandhi, Amar; Brock, John C.; Sallenger, A.H.; Bonisteel, Jamie M.; Klipp, Emily S.; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of Lidar-derived first surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the western Florida panhandle coastline, acquired October 2-4 and 7-10, 2001. The datasets are made available for use as a management tool to research scientists and natural resource managers. An innovative scanning Lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning Lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of Lidar data in an interactive or batch mode. Modules for presurvey flight line definition, flight path plotting, Lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is routinely used

  3. Screening for ATM Mutations in an African-American Population to Identify a Predictor of Breast Cancer Susceptibility

    National Research Council Canada - National Science Library

    Rosenstein, Barry S

    2006-01-01

    The hypothesis being tested in this project is that a greater proportion of African-Americans with breast cancer harbor a specific germline genetic alteration in the ATM gene or possess a particular...

  4. ATM Heterozygosity and the Development of Radiation-Induced Erectile Dysfunction and Urinary Morbidity Following Radiotherapy for Prostate Cancer

    National Research Council Canada - National Science Library

    Cesaretti, Jamie A

    2006-01-01

    The goal of this training grant project is to determine whether the prevalence of ATM carriers among prostate cancer patients treated with radiotherapy that develop erectile dysfunction and urinary...

  5. ATM Heterozygosity and the Development of Radiation-Induced Erectile Dysfunction and Urinary Morbidity Following Radiotherapy for Prostate Cancer

    National Research Council Canada - National Science Library

    Cesaretti, Jamie A

    2007-01-01

    The goal of this training grant project is to determine whether the prevalence of ATM carriers among prostate cancer patients treated with radiotherapy that develop erectile dysfunction and urinary...

  6. ATM Heterozygosity and the Development of Radiation-Induced Erectile Dysfunction and Urinary Morbidity Following Radiotherapy for Prostate Cancer

    National Research Council Canada - National Science Library

    Cesaretti, Jamie A

    2008-01-01

    The goal of this training grant project is to determine whether the prevalence of ATM carriers among prostate cancer patients treated with radiotherapy that develop erectile dysfunction and urinary...

  7. Challenges in Mentoring Software Development Projects in the High School: Analysis According to Shulman's Teacher Knowledge Base Model

    Science.gov (United States)

    Meerbaum-Salant, Orni; Hazzan, Orit

    2009-01-01

    This paper focuses on challenges in mentoring software development projects in the high school and analyzes difficulties encountered by Computer Science teachers in the mentoring process according to Shulman's Teacher Knowledge Base Model. The main difficulties that emerged from the data analysis belong to the following knowledge sources of…

  8. An Investigation of the Relationships between Goals and Software Project Escalation: Insights from Goal Setting and Goal Orientation Theories

    Science.gov (United States)

    Lee, Jong Seok

    2013-01-01

    Escalation of commitment is manifested as a behavior in which an individual resists withdrawing from a failing course of action despite negative feedback, and it is an enduring problem that occurs in a variety of situations, including R&D investment decisions and software project overruns. To date, a variety of theoretical explanations have…

  9. Aurora-B Mediated ATM Serine 1403 Phosphorylation Is Required For Mitotic ATM Activation and the Spindle Checkpoint

    OpenAIRE

    Yang, Chunying; Tang, Xi; Guo, Xiaojing; Niikura, Yohei; Kitagawa, Katsumi; Cui, Kemi; Wong, Stephen T.C.; Fu, Li; Xu, Bo

    2011-01-01

    The ATM kinase plays a critical role in the maintenance of genetic stability. ATM is activated in response to DNA damage and is essential for cell cycle checkpoints. Here, we report that ATM is activated in mitosis in the absence of DNA damage. We demonstrate that mitotic ATM activation is dependent on the Aurora-B kinase and that Aurora-B phosphorylates ATM on serine 1403. This phosphorylation event is required for mitotic ATM activation. Further, we show that loss of ATM function results in...

  10. Space Flight Software Development Software for Intelligent System Health Management

    Science.gov (United States)

    Trevino, Luis C.; Crumbley, Tim

    2004-01-01

    The slide presentation examines the Marshall Space Flight Center Flight Software Branch, including software development projects, mission critical space flight software development, software technical insight, advanced software development technologies, and continuous improvement in the software development processes and methods.

  11. Clinical software development for the Web: lessons learned from the BOADICEA project

    OpenAIRE

    Cunningham, Alex P; Antoniou, Antonis C; Easton, Douglas F

    2012-01-01

    Abstract Background In the past 20 years, society has witnessed the following landmark scientific advances: (i) the sequencing of the human genome, (ii) the distribution of software by the open source movement, and (iii) the invention of the World Wide Web. Together, these advances have provided a new impetus for clinical software development: developers now translate the products of human genomic research into clinical software tools; they use open-source programs to build them; and they use...

  12. Introduction to multiprotocol over ATM (MPOA)

    Science.gov (United States)

    Fredette, Andre N.

    1997-10-01

    Multiprotocol over ATM (MPOA) is a new protocol specified by the ATM Forum. MPOA provides a framework for effectively synthesizing bridging and routing with ATM in an environment of diverse protocols and network technologies. The primary goal of MPOA is the efficient transfer of inter-subnet unicast data in a LAN Emulation (LANE) environment. MPOA integrates LANE and the next hop resolution protocol (NHRP) to preserve the benefits of LAN Emulation, while allowing inter-subnet, internetwork layer protocol communication over ATM VCCs without requiring routers in the data path. It reduces latency and the internetwork layer forwarding load on backbone routers by enabling direct connectivity between ATM-attached edge devices (i.e., shortcuts). To establish these shortcuts, MPOA uses both routing and bridging information to locate the edge device closest to the addressed end station. By integrating LANE and NHRP, MPOA allows the physical separation of internetwork layer route calculation and forwarding, a technique known as virtual routing. This separation provides a number of key benefits including enhanced manageability and reduced complexity of internetwork layer capable edge devices. This paper provides an overview of MPOA that summarizes the goals, architecture, and key attributes of the protocol. In presenting this overview, the salient attributes of LANE and NHRP are described as well.

  13. Enhancements and Extensions of Formal Models for Risk Assessment in Software Projects

    Science.gov (United States)

    2002-09-01

    the five defect categories. Cosmetic Defects. The name that corresponds to QSM®’s cosmetic defects. Cosmetic defects can be described as deferred...California. June 2002. (Fent00) Fenton , N. E. and Neil, M., Software Metrics: Roadmap. Proceedings of the Conference on the Future of Software

  14. Development and evaluation of a digital dental modeling method based on grating projection and reverse engineering software.

    Science.gov (United States)

    Zhou, Qin; Wang, Zhenzhen; Chen, Jun; Song, Jun; Chen, Lu; Lu, Yi

    2016-01-01

    For reasons of convenience and economy, attempts have been made to transform traditional dental gypsum casts into 3-dimensional (3D) digital casts. Different scanning devices have been developed to generate digital casts; however, each has its own limitations and disadvantages. The purpose of this study was to develop an advanced method for the 3D reproduction of dental casts by using a high-speed grating projection system and noncontact reverse engineering (RE) software and to evaluate the accuracy of the method. The methods consisted of 3 main steps: the scanning and acquisition of 3D dental cast data with a high-resolution grating projection system, the reconstruction and measurement of digital casts with RE software, and the evaluation of the accuracy of this method using 20 dental gypsum casts. The common anatomic landmarks were measured directly on the gypsum casts with a Vernier caliper and on the 3D digital casts with the Geomagic software measurement tool. Data were statistically assessed with the t test. The grating projection system had a rapid scanning speed, and smooth 3D dental casts were obtained. The mean differences between the gypsum and 3D measurements were approximately 0.05 mm, and no statistically significant differences were found between the 2 methods (P>.05), except for the measurements of the incisor tooth width and maxillary arch length. A method for the 3D reconstruction of dental casts was developed by using a grating projection system and RE software. The accuracy of the casts generated using the grating projection system was comparable with that of the gypsum casts. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  15. Recent studies on the ATM gene

    International Nuclear Information System (INIS)

    Lavin, M.F.; Khanna, K.K.; Waters, D.

    1996-01-01

    Full text: Radiosensitivity is a universal characteristic of ataxia-telangiectasia (A-T), observed after exposure of patients and of cells in culture to radiation. This sensitivity is manifested as higher levels of radiation-induced chromosomal aberrations and reduced survival compared to controls. The gene for A-T was mapped to chromosome 11q 22-23 seven years ago and more recently we have been involved in the cloning of a single gene, ATM (ataxia-telangiectasia mutated), mutated in this syndrome. ATM is a large gene, approximately 150 kb in size, composed of 66 exons and codes for a major mRNA of 13 kb with a predicted open reading frame of 9.135 kb. It is not yet known what activity the ATM gene product possesses, but the ralatedness of this gene sequence to the phosphatidylinositol 3-kinase gene family supports a role for ATM in intracellular signalling. Considerable information is already available on defective signalling through the p53 damage-inducible pathway in A-T. This includes failure to arrest at either the G1/S or G2/M checkpoints as well as radioresistant DNA synthesis. A reduced and/or delayed response in the induction of p53 after exposure of A-T cells to ionizing radiation can account for the defective G1/S checkpoint. More recently we have demonstrated that the ATM gene product is involved in the control of multiple cell cycle checkpoints. Antibodies prepared against ATM peptides demonstrate the presence of a protein 350 kDa in size, which is the predicted size for this protein based on open reading frame of 9 kb. This protein is present both in the nucleus and in the cytoplasm where it is present in vesicular structures. As expected from mutation data the ATM protein is absent in cells from some patients with A-T. The cloning of the ATM gene will allow for screening of radiosensitive patients for mutations in this gene and will provide a means of identifying interacting proteins and thus an understanding of how it functions

  16. Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002

    International Nuclear Information System (INIS)

    Bernstein, Jonine L; Seminara, Daniela; Børresen-Dale, Anne-Lise

    2002-01-01

    The role of ataxia-telangiectasia mutated (ATM) heterozygosity in cancer is uncertain. In vitro studies of cells from ATM heterozygotes provide strong evidence of radiation sensitivity. Some, but not all, clinical studies suggest an increased risk of breast cancer among ATM gene carriers, and this risk may be greater among those exposed to radiation. This possible excess risk of breast cancer associated with ATM heterozygosity constitutes the basis for several genetic epidemiological studies designed to clarify the role that the ATM gene plays in the etiology of breast and other cancers. The primary focus of this international, multidisciplinary, National Cancer Institute-sponsored workshop was to discuss ongoing and planned epidemiologic studies aimed at understanding the complexities of the ATM gene and its role in carcinogenesis. The invited participants were from diverse disciplines including molecular and clinical genetics, radiation biology and physics, epidemiology, biostatistics, pathology, and medicine. In the present meeting report, the aims of each project are described

  17. Metadata database and data analysis software for the ground-based upper atmospheric data developed by the IUGONET project

    Science.gov (United States)

    Hayashi, H.; Tanaka, Y.; Hori, T.; Koyama, Y.; Shinbori, A.; Abe, S.; Kagitani, M.; Kouno, T.; Yoshida, D.; Ueno, S.; Kaneda, N.; Yoneda, M.; Tadokoro, H.; Motoba, T.; Umemura, N.; Iugonet Project Team

    2011-12-01

    The Inter-university Upper atmosphere Global Observation NETwork (IUGONET) is a Japanese inter-university project by the National Institute of Polar Research (NIPR), Tohoku University, Nagoya University, Kyoto University, and Kyushu University to build a database of metadata for ground-based observations of the upper atmosphere. The IUGONET institutes/universities have been collecting various types of data by radars, magnetometers, photometers, radio telescopes, helioscopes, etc. at various locations all over the world and at various altitude layers from the Earth's surface to the Sun. The metadata database will be of great help to researchers in efficiently finding and obtaining these observational data spread over the institutes/universities. This should also facilitate synthetic analysis of multi-disciplinary data, which will lead to new types of research in the upper atmosphere. The project has also been developing a software to help researchers download, visualize, and analyze the data provided from the IUGONET institutes/universities. The metadata database system is built on the platform of DSpace, which is an open source software for digital repositories. The data analysis software is written in the IDL language with the TDAS (THEMIS Data Analysis Software suite) library. These products have been just released for beta-testing.

  18. Comparison of performance between TCP/IP over ATM e ATM nativo

    OpenAIRE

    Marcelo Silva Freitas

    2001-01-01

    Com o recente desenvolvimento de tecnologias de redes de altas taxas de transmissão, tais como Asynchronous Transfer Mode (ATM), o problema da carência por largura de banda foi solucionado. A questão atual é a implementação de sistemas que suportem os protocolos ATM de forma nativa e integral. Atualmente tem-se utilizado aplicativos tradicionais baseados nos protocolos TCP(UDP)/IP no topo da pilha de protocolos ATM. Tal modelo traz redundâncias que implicam diretamente em aumento de overhead ...

  19. Sustainability in Open Source Software Commons: Lessons Learned from an Empirical Study of SourceForge Projects

    Directory of Open Access Journals (Sweden)

    Charles M. Schweik

    2013-01-01

    Full Text Available In this article, we summarize a five-year US National Science Foundation funded study designed to investigate the factors that lead some open source projects to ongoing collaborative success while many others become abandoned. Our primary interest was to conduct a study that was closely representative of the population of open source software projects in the world, rather than focus on the more-often studied, high-profile successful cases. After building a large database of projects (n=174,333 and implementing a major survey of open source developers (n=1403, we were able to conduct statistical analyses to investigate over forty theoretically-based testable hypotheses. Our data firmly support what we call the conventional theory of open source software, showing that projects start small, and, in successful cases, grow slightly larger in terms of team size. We describe the “virtuous circle” supporting conventional wisdom of open source collaboration that comes out of this analysis, and we discuss two other interesting findings related to developer motivations and how team members find each other. Each of these findings is related to the sustainability of these projects.

  20. Two-step web-mining approach to study geology/geophysics-related open-source software projects

    Science.gov (United States)

    Behrends, Knut; Conze, Ronald

    2013-04-01

    Geology/geophysics is a highly interdisciplinary science, overlapping with, for instance, physics, biology and chemistry. In today's software-intensive work environments, geoscientists often encounter new open-source software from scientific fields that are only remotely related to the own field of expertise. We show how web-mining techniques can help to carry out systematic discovery and evaluation of such software. In a first step, we downloaded ~500 abstracts (each consisting of ~1 kb UTF-8 text) from agu-fm12.abstractcentral.com. This web site hosts the abstracts of all publications presented at AGU Fall Meeting 2012, the world's largest annual geology/geophysics conference. All abstracts belonged to the category "Earth and Space Science Informatics", an interdisciplinary label cross-cutting many disciplines such as "deep biosphere", "atmospheric research", and "mineral physics". Each publication was represented by a highly structured record with ~20 short data attributes, the largest authorship-record being the unstructured "abstract" field. We processed texts of the abstracts with the statistics software "R" to calculate a corpus and a term-document matrix. Using R package "tm", we applied text-mining techniques to filter data and develop hypotheses about software-development activities happening in various geology/geophysics fields. Analyzing the term-document matrix with basic techniques (e.g., word frequencies, co-occurences, weighting) as well as more complex methods (clustering, classification) several key pieces of information were extracted. For example, text-mining can be used to identify scientists who are also developers of open-source scientific software, and the names of their programming projects and codes can also be identified. In a second step, based on the intermediate results found by processing the conference-abstracts, any new hypotheses can be tested in another webmining subproject: by merging the dataset with open data from github

  1. The cleanroom case study in the Software Engineering Laboratory: Project description and early analysis

    Science.gov (United States)

    Green, Scott; Kouchakdjian, Ara; Basili, Victor; Weidow, David

    1990-01-01

    This case study analyzes the application of the cleanroom software development methodology to the development of production software at the NASA/Goddard Space Flight Center. The cleanroom methodology emphasizes human discipline in program verification to produce reliable software products that are right the first time. Preliminary analysis of the cleanroom case study shows that the method can be applied successfully in the FDD environment and may increase staff productivity and product quality. Compared to typical Software Engineering Laboratory (SEL) activities, there is evidence of lower failure rates, a more complete and consistent set of inline code documentation, a different distribution of phase effort activity, and a different growth profile in terms of lines of code developed. The major goals of the study were to: (1) assess the process used in the SEL cleanroom model with respect to team structure, team activities, and effort distribution; (2) analyze the products of the SEL cleanroom model and determine the impact on measures of interest, including reliability, productivity, overall life-cycle cost, and software quality; and (3) analyze the residual products in the application of the SEL cleanroom model, such as fault distribution, error characteristics, system growth, and computer usage.

  2. Cost Control and Performance Review of Software Projects by Using the Earned Value Management

    Directory of Open Access Journals (Sweden)

    Felician ALECU

    2014-08-01

    Full Text Available EVM (Earned Value Management is a method that can be successfully used to measure the performance of a project from the cost and schedule points of view. Initially developed for the US government programs in the 60s, it later becomes an important feature of any modern project management practice thanks to its simplicity and efficiency in signaling project anomalies in time. EVM become extremely popular because it can be equally applied for any project in any industry.

  3. High-school software development project helps increasing students' awareness of geo-hydrological hazards and their risks

    Science.gov (United States)

    Marchesini, Ivan; Rossi, Mauro; Balducci, Vinicio; Salvati, Paola; Guzzetti, Fausto; Bianchini, Andrea; Grzeleswki, Emanuell; Canonico, Andrea; Coccia, Rita; Fiorucci, Gianni Mario; Gobbi, Francesca; Ciuchetti, Monica

    2015-04-01

    In Italy, inundation and landslides are widespread phenomena that impact the population and cause significant economic damage to private and public properties. The perception of the risk posed by these natural geo-hydrological hazards varies geographically and in time. The variation in the perception of the risks has negative consequences on risk management, and limits the adoption of effective risk reduction strategies. We maintain that targeted education can foster the understanding of geo-hydrological hazards, improving their perception and the awareness of the associated risk. Collaboration of a research center experienced in geo-hydrological hazards and risks (CNR IRPI, Perugia) and a high school (ITIS Alessandro Volta, Perugia) has resulted in the design and execution of a project aimed at improving the perception of geo-hydrological risks in high school students and teachers through software development. In the two-year project, students, high school teachers and research scientists have jointly developed software broadly related to landslide and flood hazards. User requirements and system specifications were decided to facilitate the distribution and use of the software among students and their peers. This allowed a wider distribution of the project results. We discuss two prototype software developed by the high school students, including an application of augmented reality for improved dissemination of information of landslides and floods with human consequences in Italy, and a crowd science application to allow students (and others, including their families and friends) to collect information on landslide and flood occurrence exploiting modern mobile devices. This information can prove important e.g., for the validation of landslide forecasting models.

  4. ATM protein is deficient in over 40% of lung adenocarcinomas.

    Science.gov (United States)

    Villaruz, Liza C; Jones, Helen; Dacic, Sanja; Abberbock, Shira; Kurland, Brenda F; Stabile, Laura P; Siegfried, Jill M; Conrads, Thomas P; Smith, Neil R; O'Connor, Mark J; Pierce, Andrew J; Bakkenist, Christopher J

    2016-09-06

    Lung cancer is the leading cause of cancer-related mortality in the USA and worldwide, and of the estimated 1.2 million new cases of lung cancer diagnosed every year, over 30% are lung adenocarcinomas. The backbone of 1st-line systemic therapy in the metastatic setting, in the absence of an actionable oncogenic driver, is platinum-based chemotherapy. ATM and ATR are DNA damage signaling kinases activated at DNA double-strand breaks (DSBs) and stalled and collapsed replication forks, respectively. ATM protein is lost in a number of cancer cell lines and ATR kinase inhibitors synergize with cisplatin to resolve xenograft models of ATM-deficient lung cancer. We therefore sought to determine the frequency of ATM loss in a tissue microarray (TMA) of lung adenocarcinoma. Here we report the validation of a commercial antibody (ab32420) for the identification of ATM by immunohistochemistry and estimate that 61 of 147 (41%, 95% CI 34%-50%) cases of lung adenocarcinoma are negative for ATM protein expression. As a positive control for ATM staining, nuclear ATM protein was identified in stroma and immune infiltrate in all evaluable cases. ATM loss in lung adenocarcinoma was not associated with overall survival. However, our preclinical findings in ATM-deficient cell lines suggest that ATM could be a predictive biomarker for synergy of an ATR kinase inhibitor with standard-of-care cisplatin. This could improve clinical outcome in 100,000's of patients with ATM-deficient lung adenocarcinoma every year.

  5. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase

    Czech Academy of Sciences Publication Activity Database

    Bražina, Jan; Švadlenka, Jan; Macůrek, Libor; Anděra, Ladislav; Hodný, Zdeněk; Bartek, Jiří; Hanzlíková, Hana

    2015-01-01

    Roč. 14, č. 3 (2015), s. 375-387 ISSN 1538-4101 R&D Projects: GA ČR GPP305/11/P683 Institutional support: RVO:68378050 Keywords : ATM * DAXX * DNA damage * p53 * Wip1 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.952, year: 2015

  6. Sandia software guidelines: Software quality planning

    Energy Technology Data Exchange (ETDEWEB)

    1987-08-01

    This volume is one in a series of Sandia Software Guidelines intended for use in producing quality software within Sandia National Laboratories. In consonance with the IEEE Standard for Software Quality Assurance Plans, this volume identifies procedures to follow in producing a Software Quality Assurance Plan for an organization or a project, and provides an example project SQA plan. 2 figs., 4 tabs.

  7. Technology survey of computer software as applicable to the MIUS project

    Science.gov (United States)

    Fulbright, B. E.

    1975-01-01

    Existing computer software, available from either governmental or private sources, applicable to modular integrated utility system program simulation is surveyed. Several programs and subprograms are described to provide a consolidated reference, and a bibliography is included. The report covers the two broad areas of design simulation and system simulation.

  8. Cross Sectional Study of Agile Software Development Methods and Project Performance

    Science.gov (United States)

    Lambert, Tracy

    2011-01-01

    Agile software development methods, characterized by delivering customer value via incremental and iterative time-boxed development processes, have moved into the mainstream of the Information Technology (IT) industry. However, despite a growing body of research which suggests that a predictive manufacturing approach, with big up-front…

  9. Evaluating Managerial Styles for System Development Life Cycle Stages to Ensure Software Project Success

    Science.gov (United States)

    Kocherla, Showry

    2012-01-01

    Information technology (IT) projects are considered successful if they are completed on time, within budget, and within scope. Even though, the required tools and methodologies are in place, IT projects continue to fail at a higher rate. Current literature lacks explanation for success within the stages of system development life-cycle (SDLC) such…

  10. The Activity-Based Computing Project - A Software Architecture for Pervasive Computing Final Report

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind

    . Special attention should be drawn to publication [25], which gives an overview of the ABC project to the IEEE Pervasive Computing community; the ACM CHI 2006 [19] paper that documents the implementation of the ABC technology; and the ACM ToCHI paper [12], which is the main publication of the project......, documenting all of the project’s four objectives. All of these publication venues are top-tier journals and conferences within computer science. From a business perspective, the project had the objective of incorporating relevant parts of the ABC technology into the products of Medical Insight, which has been...... done. Moreover, partly based on the research done in the ABC project, the company Cetrea A/S has been founded, which incorporate ABC concepts and technologies in its products. The concepts of activity-based computing have also been researched in cooperation with IBM Research, and the ABC project has...

  11. SITEGI Project: Applying Geotechnologies to Road Inspection. Sensor Integration and software processing

    Directory of Open Access Journals (Sweden)

    J. Martínez-Sánchez

    2013-10-01

    Full Text Available Infrastructure management represents a critical economic milestone. The current decision-making process in infrastructure rehabilitation is essentially based on qualitative parameters obtained from visual inspections and subject to the ability of technicians. In order to increase both efficiency and productivity in infrastructure management, this work addresses the integration of different instrumentation and sensors in a mobile mapping vehicle. This vehicle allows the continuous recording of quantitative data suitable for roadside inspection. The geometric integration and synchronization of these sensors is achieved through hardware and/or software strategies that permit the georeferencing of the data obtained with each sensor. In addition, a visualization software for simpler data management was implemented using Qt framework, PCL library and C++. As a result, the developed system supports the decision-making in road inspection, providing quantitative information suitable for sophisticated analysis systems.

  12. Configuration management plan. System definition and project development. Repository Based Software Engineering (RBSE) program

    Science.gov (United States)

    Mckay, Charles

    1991-01-01

    This is the configuration management Plan for the AdaNet Repository Based Software Engineering (RBSE) contract. This document establishes the requirements and activities needed to ensure that the products developed for the AdaNet RBSE contract are accurately identified, that proposed changes to the product are systematically evaluated and controlled, that the status of all change activity is known at all times, and that the product achieves its functional performance requirements and is accurately documented.

  13. Optimal reliability allocation for large software projects through soft computing techniques

    DEFF Research Database (Denmark)

    Madsen, Henrik; Albeanu, Grigore; Popentiu-Vladicescu, Florin

    2012-01-01

    or maximizing the system reliability subject to budget constraints. These kinds of optimization problems were considered both in deterministic and stochastic frameworks in literature. Recently, the intuitionistic-fuzzy optimization approach was considered as a soft computing successful modelling approach....... Firstly, a review on existing soft computing approaches to optimization is given. The main section extends the results considering self-organizing migrating algorithms for solving intuitionistic-fuzzy optimization problems attached to complex fault-tolerant software architectures which proved...

  14. Barriers and Facilitators of Iranian Elderly in Use of ATM Machines: A Qualitative Research in the Way of Cultural Probes

    Directory of Open Access Journals (Sweden)

    Azade Mokhberi

    2013-10-01

    Full Text Available Objectives: Having considering to the rate of increasing of elder people population in Iran, is preadicted that in the next thirty years the number of elderly people who need to independently work with electronic devices such as ATMs machineswill be significantly increased while there is no sufficient studies in order to modification of these devices considering physical, mental and psychology abilities of the elder people. Methods & Materials: This article is part of a qualitative study with cultural Probes Methodology to explore the needs and barriers and facilitators in the work ATMs. This study collected data through observation, interview and documentation participants respectively. This qualitative study was conducted in two stages. In the first phase interviewed with 30 elderly people in Tehran.In the second Phase according to cultural probes method we designed a package to extract the needs and problems associated with ATM. purposive sample of 10 elderly people in Tehran, 6 participants were female and 4 males. Interviews continued until data saturation, data Were coded and categorized by content analysis method. Results: Six key factors required for the design of ATM data were extracted according to the Iranian people, that pleasant, unpleasant, wants and desires, problems and obstacles, banking and mishaps. that the classification of barriers and facilitating factors these factors were extracted for the elderly. The results showed a much higher barriers to Elderly people using ATMs in facilitating conditions are present. Conclusion: According to the Iranian people using ATMs barrier is recommended to attention to ATMs in the the environment, nature and location of the installation, ATMs appear particularly relevant in the context of software that can be tailored to the elderly should be done. Finally, it is suggested that future studies in different groups of people, especially older people with disabilities and low literacy are doing.

  15. Supervision software for string 2 magnet test facility of large hadron collider project

    International Nuclear Information System (INIS)

    Mayya, Y.S.; Sanadhya, Vivek; Lal, Pradeep; Goel, Vijay; Mukhopadhyay, S.; Saha, Shilpi

    2001-01-01

    The Supervisory Control and Data Acquisition (SCADA) software for the String 2 test facility at CERN, Geneva is developed by BARC under the framework of CERN-DAE collaboration for LHC. The supervision application is developed using PCVue32 SCADA/MMI software. The String 2 test facility prototypes one full cell of LHC and is aimed at studying and validating the individual and collective behaviour of the superconducting magnets, before installing in the tunnel. The software integrates monitoring and supervisory control of all the main subsystems of String 2 such as Cryogenics, Vacuum, Power converters, Magnet protection, Energy extraction and interlock systems. It incorporates animated process synoptics, loop and equipment control panels, configurable trend windows for real-time and historical trending of process parameters, user settability for interlock and alarm thresholds, logging of process events, equipment faults and operator activity. The plant equipment are controlled by a variety of field located Programmable Logic Controllers and VME crates which communicate process IO to the central IO server using both vendor specific and custom protocols. The system leverages OPC (OLE for Process Controls) technology for realising a generic IO server. A large number of geographically distributed client stations are arranged to provide the process specific operator interface and these are connected to the Main IO server over CERN wide intranet and internet. (author)

  16. ATM supports gammaherpesvirus replication by attenuating type I interferon pathway.

    Science.gov (United States)

    Darrah, Eric J; Stoltz, Kyle P; Ledwith, Mitchell; Tarakanova, Vera L

    2017-10-01

    Ataxia-Telangiectasia mutated (ATM) kinase participates in multiple networks, including DNA damage response, oxidative stress, and mitophagy. ATM also supports replication of diverse DNA and RNA viruses. Gammaherpesviruses are prevalent cancer-associated viruses that benefit from ATM expression during replication. This proviral role of ATM had been ascribed to its signaling within the DNA damage response network; other functions of ATM have not been considered. In this study increased type I interferon (IFN) responses were observed in ATM deficient gammaherpesvirus-infected macrophages. Using a mouse model that combines ATM and type I IFN receptor deficiencies we show that increased type I IFN response in the absence of ATM fully accounts for the proviral role of ATM during gammaherpesvirus replication. Further, increased type I IFN response rendered ATM deficient macrophages more susceptible to antiviral effects of type II IFN. This study identifies attenuation of type I IFN responses as the primary mechanism underlying proviral function of ATM during gammaherpesvirus infection. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Atm reactivation reverses ataxia telangiectasia phenotypes in vivo.

    Science.gov (United States)

    Di Siena, Sara; Campolo, Federica; Gimmelli, Roberto; Di Pietro, Chiara; Marazziti, Daniela; Dolci, Susanna; Lenzi, Andrea; Nussenzweig, Andre; Pellegrini, Manuela

    2018-02-22

    Hereditary deficiencies in DNA damage signaling are invariably associated with cancer predisposition, immunodeficiency, radiation sensitivity, gonadal abnormalities, premature aging, and tissue degeneration. ATM kinase has been established as a central player in DNA double-strand break repair and its deficiency causes ataxia telangiectasia, a rare, multi-system disease with no cure. So ATM represents a highly attractive target for the development of novel types of gene therapy or transplantation strategies. Atm tamoxifen-inducible mouse models were generated to explore whether Atm reconstitution is able to restore Atm function in an Atm-deficient background. Body weight, immunodeficiency, spermatogenesis, and radioresistance were recovered in transgenic mice within 1 month from Atm induction. Notably, life span was doubled after Atm restoration, mice were protected from thymoma and no cerebellar defects were observed. Atm signaling was functional after DNA damage in vivo and in vitro. In summary, we propose a new Atm mouse model to investigate novel therapeutic strategies for ATM activation in ataxia telangiectasia disease.

  18. ATM induction insufficiency in a radiosensitive breast-cancer patient

    International Nuclear Information System (INIS)

    Clarke, R.A.; Fang, Z.H.; Marr, P.J.; Kearsley, J.H.; Papadatos, G.; Lee, C.S.; University of Sydney, Camperdown, NSW

    2002-01-01

    ATM induction insufficiency in a radiosensitive breast-cancer patient The ataxia telangiectasia (A-T) gene (ATM) is a dominant breast cancer gene with tumour suppressor activity. ATM also regulates cellular sensitivity to ionising radiation (IR) presumably through its role as a facilitator of DNA repair. In normal cells and tissues the ATM protein is rapidly induced by IR to threshold/maximum levels. The kinase function of the ATM protein is also rapidly activated in response to IR. The fact that women carriers of ATM mutations can have an increased risk of developing breast cancer and that many sporadic breast tumours have reduced levels of the ATM protein broadens the scope of ATM's tumour suppressor within the breast. This report describes the downregulation of ATM protein levels in a radiosensitive breast cancer patient. Postinduction ATM levels were up to tenfold lower in the patient's fresh tissues compared to normal controls. These results might indicate a much broader role for ATM anomalies in breast cancer aetiology. Copyright (2002) Blackwell Science Pty Ltd

  19. Performance analysis of ATM/DQDB interworking

    DEFF Research Database (Denmark)

    Christiansen, Henning; Kvols, Kenn

    1992-01-01

    The cell loss ratio and cell delay variation of a distributed-queue dual-bus (DQDB) network receiving traffic from a number of asynchronous transfer mode (ATM) connections are considered. Every connection carries either connection oriented or connectionless traffic. In the analysis of the access ...... to the bus, it is shown that consecutive service times of the local access queue are correlated. Two models, one of which includes the correlation, are presented. The correlation effect is illustrated and the models are evaluated by means of a number of simulation cases......The cell loss ratio and cell delay variation of a distributed-queue dual-bus (DQDB) network receiving traffic from a number of asynchronous transfer mode (ATM) connections are considered. Every connection carries either connection oriented or connectionless traffic. In the analysis of the access...

  20. R PROJECT: SU APLICACIÓN COMO SOFTWARE LIBRE PARA ANÁLISIS EN COMPONENTES PRINCIPALES (R PROJECT: ITS USE AS OPEN SOURCE FOR PRINCIPAL COMPONENTS ANALYSIS

    Directory of Open Access Journals (Sweden)

    Bolaños Guerrero Fabricio

    2011-06-01

    Full Text Available Resumen:Este artículo es producto de un proyecto de investigación realizado en colaboración con profesores de la Escuela de Matemáticas de la Universidad de Costa Rica (UCR, para dar a conocer una opción de software estadístico llamado R Project®. Con este paquete es posible hacer Análisis en Componentes Principales (ACP y representar los resultados usando el Plano Principal y el Círculo de Correlaciones, como herramientas para poder realizar una mejor interpretación de los datos de la tabla (individuos y variables. El software R es de distribución libre, su implementación es sencilla y no requiere de mayores recursos informáticos. Dentro de sus diversas aplicaciones está el ACP, que es una herramienta que se utiliza para la interpretación de la información presentada en una tabla de datos cuantitativos; por lo tanto, las personas investigadoras de diferentes áreas tienen una opción económica y sencilla para realizar Análisis de Datos. Se llevan a cabo dos ejemplos de ACP, donde se muestra un posible uso de la herramienta y se dan las instrucciones sobre cómo realizarlo paso a paso.Abstract: This article is a product of a research project made in collaboration with teachers of the Mathematics School of the University of Costa Rica, in order to show an option of statistical software called “R Project®”. With this software, it is possible to do an Analysis in the Principal Components (PCA and to represent the results using the “principal plane” and the “circle of correlations”, as tools to have a better interpretation of the data in the chart (individuals and variables. The software R is for free distribution, its implementation is simple and it does not require great computer resources. Among its diverse applications there is the PCA, which is a tool used to interpret the information showed in a chart with quantitative data; therefore, the researchers of different areas have a cheap and simple option to do a Data

  1. Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response

    Science.gov (United States)

    Lee, Hong-Jen; Lan, Li; Peng, Guang; Chang, Wei-Chao; Hsu, Ming-Chuan; Wang, Ying-Nai; Cheng, Chien-Chia; Wei, Leizhen; Nakajima, Satoshi; Chang, Shih-Shin; Liao, Hsin-Wei; Chen, Chung-Hsuan; Lavin, Martin; Ang, K Kian; Lin, Shiaw-Yih; Hung, Mien-Chie

    2015-01-01

    Ataxia telangiectasia mutated (ATM) mediates DNA damage response by controling irradiation-induced foci formation, cell cycle checkpoint, and apoptosis. However, how upstream signaling regulates ATM is not completely understood. Here, we show that upon irradiation stimulation, ATM associates with and is phosphorylated by epidermal growth factor receptor (EGFR) at Tyr370 (Y370) at the site of DNA double-strand breaks. Depletion of endogenous EGFR impairs ATM-mediated foci formation, homologous recombination, and DNA repair. Moreover, pretreatment with an EGFR kinase inhibitor, gefitinib, blocks EGFR and ATM association, hinders CHK2 activation and subsequent foci formation, and increases radiosensitivity. Thus, we reveal a critical mechanism by which EGFR directly regulates ATM activation in DNA damage response, and our results suggest that the status of ATM Y370 phosphorylation has the potential to serve as a biomarker to stratify patients for either radiotherapy alone or in combination with EGFR inhibition. PMID:25601159

  2. Study of ATM Phosphorylation by Cdk5 in Neuronal Cells.

    Science.gov (United States)

    She, Hua; Mao, Zixu

    2017-01-01

    The phosphatidylinositol-3-kinase-like kinase ATM (ataxia-telangiectasia mutated) plays a central role in coordinating the DNA damage responses including cell cycle checkpoint control, DNA repair, and apoptosis. Mutations of ATM cause a spectrum of defects ranging from neurodegeneration to cancer predisposition. We previously showed that Cdk5 (cyclin-dependent kinase 5) is activated by DNA damage and directly phosphorylates ATM at serine 794 in postmitotic neurons. Phosphorylation at serine 794 precedes and is required for ATM autophosphorylation at serine 1981, and activates ATM kinase activity. Cdk5-ATM pathway plays a crucial role in DNA damage-induced neuronal injury. This chapter describes protocols used in analyzing ATM phosphorylation by Cdk5 in CGNs (cerebellar granule neurons) and its effects on neuronal survival.

  3. Preservation of methane hydrate at 1 atm

    Science.gov (United States)

    Stern, L.A.; Circone, S.; Kirby, S.H.; Durham, W.B.

    2001-01-01

    A "pressure-release" method that enables reproducible bulk preservation of pure, porous, methane hydrate at conditions 50 to 75 K above its equilibrium T (193 K) at 1 atm is refined. The amount of hydrate preserved by this method appears to be greatly in excess of that reported in the previous citations, and is likely the result of a mechanism different from ice shielding.

  4. Preventive Methods for ATM Mode Control

    OpenAIRE

    Ivan Baronak; Robert Trska

    2004-01-01

    Broadband transfer mode ATM represent one of alternative solutions for growing requirements on transfer capabilities. Its advantage is an effort for provisions of guaranteed quality of transport services with preservations of high transfer rate. This property is covered by several mechanisms, which role is to control not only the traffic of existing connections, but also the admission of new ones and prevent the violation of requirements on transport quality of existing and new connections.

  5. Automated water analyser computer supported system (AWACSS) Part I: Project objectives, basic technology, immunoassay development, software design and networking.

    Science.gov (United States)

    Tschmelak, Jens; Proll, Guenther; Riedt, Johannes; Kaiser, Joachim; Kraemmer, Peter; Bárzaga, Luis; Wilkinson, James S; Hua, Ping; Hole, J Patrick; Nudd, Richard; Jackson, Michael; Abuknesha, Ram; Barceló, Damià; Rodriguez-Mozaz, Sara; de Alda, Maria J López; Sacher, Frank; Stien, Jan; Slobodník, Jaroslav; Oswald, Peter; Kozmenko, Helena; Korenková, Eva; Tóthová, Lívia; Krascsenits, Zoltan; Gauglitz, Guenter

    2005-02-15

    A novel analytical system AWACSS (automated water analyser computer-supported system) based on immunochemical technology has been developed that can measure several organic pollutants at low nanogram per litre level in a single few-minutes analysis without any prior sample pre-concentration nor pre-treatment steps. Having in mind actual needs of water-sector managers related to the implementation of the Drinking Water Directive (DWD) (98/83/EC, 1998) and Water Framework Directive WFD (2000/60/EC, 2000), drinking, ground, surface, and waste waters were major media used for the evaluation of the system performance. The instrument was equipped with remote control and surveillance facilities. The system's software allows for the internet-based networking between the measurement and control stations, global management, trend analysis, and early-warning applications. The experience of water laboratories has been utilised at the design of the instrument's hardware and software in order to make the system rugged and user-friendly. Several market surveys were conducted during the project to assess the applicability of the final system. A web-based AWACSS database was created for automated evaluation and storage of the obtained data in a format compatible with major databases of environmental organic pollutants in Europe. This first part article gives the reader an overview of the aims and scope of the AWACSS project as well as details about basic technology, immunoassays, software, and networking developed and utilised within the research project. The second part article reports on the system performance, first real sample measurements, and an international collaborative trial (inter-laboratory tests) to compare the biosensor with conventional anayltical methods.

  6. SOFTWARE IMPLEMENTATION OF FORMING OF COLOR-BASED CARDS FOR ASSESSMENT OF EARLY STAGES INNOVATION PROJECTS

    Directory of Open Access Journals (Sweden)

    Ekaterina I. Bragina

    2015-01-01

    Full Text Available The article deals with functional program that allows to generate a visualrepresentation of the shareholder tothe innovative project early stage ofdevelopment, formed a color-based cards.

  7. Transportation research synthesis : state DOT experiences with Primavera P6 project management software.

    Science.gov (United States)

    2010-03-01

    The eight agencies we interviewed all reported general satisfaction with Primavera P6 as a project management tool within their organizations, although they noted that a significant commitment to training is required. Most states have not implemented...

  8. Specialized software utilities for gamma ray spectrometry. Final report of a co-ordinated research project 1996-2000

    International Nuclear Information System (INIS)

    2002-03-01

    A Co-ordinated Research Project (CRP) on Software Utilities for Gamma Ray Spectrometry was initiated by the International Atomic Energy Agency in 1996 for a three year period. In the CRP several basic applications of nuclear data handling were assayed which also dealt with the development of PC computer codes for various spectrometric purposes. The CRP produced several software packages: for the analysis of low level NaI spectra; user controlled analysis of gamma ray spectra from HPGe detectors; a set of routines for the definition of the detector resolution function and for the unfolding of experimental annihilation spectra; a program for the generation of gamma ray libraries for specific applications; a program to calculate true coincidence corrections; a program to calculate full-energy peak efficiency calibration curve for homogenous cylindrical sample geometries including self-attenuation correction; and a program for the library driven analysis of gamma ray spectra and for the quantification of radionuclide content in samples. In addition, the CRP addressed problems of the analysis of naturally occurring radioactive soil material gamma ray spectra, questions of quality assurance and quality control in gamma ray spectrometry, and verification of the expert system SHAMAN for the analysis of air filter spectra obtained within the framework of the Comprehensive Nuclear Test Ban Treaty. This TECDOC contains 10 presentations delivered at the meeting with the description of the software developed. Each of the papers has been indexed separately

  9. Results of a Survey Software Development Project Management in the U.S. Aerospace Industry. Volume II. Project Management Techniques, Procedures and Tools.

    Science.gov (United States)

    1979-12-18

    I Z I UO W-1 eu 0 - 0 tD CL 0, 0 -I7 NW 2 - x M.j a CL W2 X 41 a ~ 0 0,a 4~~ 0 Z .D .J 0 2. N 0 ~N IU 0 4 - 2 0 ~. 0 Q. ’o ~ 0, 𔃺e U - U ~- 0, 0 -a...0 .44 A A A Ao 0 - 2. -U 2- 4’ A 4’ A o .~ 0 .~ 2. flJ 2. A Ao ~. a 2. 𔃾 2- @2 @2 @2 A 0 .~. a I- 2. Xii - 0 2 @2 ON AXe Re 2- Oi. K A.. A A AU .40...Project manager or person appointed by him SE/ TD project manager b. Senior ADP Manager Director Director computer programming Software program design

  10. Global Software Engineering: A Software Process Approach

    Science.gov (United States)

    Richardson, Ita; Casey, Valentine; Burton, John; McCaffery, Fergal

    Our research has shown that many companies are struggling with the successful implementation of global software engineering, due to temporal, cultural and geographical distance, which causes a range of factors to come into play. For example, cultural, project managementproject management and communication difficulties continually cause problems for software engineers and project managers. While the implementation of efficient software processes can be used to improve the quality of the software product, published software process models do not cater explicitly for the recent growth in global software engineering. Our thesis is that global software engineering factors should be included in software process models to ensure their continued usefulness in global organisations. Based on extensive global software engineering research, we have developed a software process, Global Teaming, which includes specific practices and sub-practices. The purpose is to ensure that requirements for successful global software engineering are stipulated so that organisations can ensure successful implementation of global software engineering.

  11. Open-Source Development Experiences in Scientific Software: The HANDE Quantum Monte Carlo Project

    Directory of Open Access Journals (Sweden)

    J. S. Spencer

    2015-11-01

    Full Text Available The HANDE quantum Monte Carlo project offers accessible stochastic algorithms for general use for scientists in the field of quantum chemistry. HANDE is an ambitious and general high-performance code developed by a geographically-dispersed team with a variety of backgrounds in computational science. In the course of preparing a public, open-source release, we have taken this opportunity to step back and look at what we have done and what we hope to do in the future. We pay particular attention to development processes, the approach taken to train students joining the project, and how a flat hierarchical structure aids communication.

  12. Digital image management project for dermatological health care environments: a new dedicated software and review of the literature.

    Science.gov (United States)

    Rubegni, Pietro; Nami, Niccolò; Poggiali, Sara; Tataranno, Domenico; Fimiani, M

    2009-05-01

    Because the skin is the only organ completely accessible to visual examination, digital technology has therefore attracted the attention of dermatologists for documenting, monitoring, measuring and classifying morphological manifestations. To describe a digital image management system dedicated to dermatological health care environments and to compare it with other existing softwares for digital image storage. We designed a reliable hardware structure that could ensure future scaling, because storage needs tend to grow exponentially. For the software, we chose a client-web server application based on a relational database and with a 'minimalist' user interface. We developed a software with a ready-made, adaptable index of skin pathologies. It facilitates classification by pathology, patient and visit, with an advanced search option allowing access to all images according to personalized criteria. The software also offers the possibility of comparing two or more digital images (follow-up). The fact that the archives of years of digital photos acquired and saved on PCs can easily be entered in the program distinguishes it from the others in the market. This option is fundamental for accessing all the photos taken in years of practice in the program without entering them one by one. The program is available to any user connected to the local Intranet and the system may directly be available in the future from the Internet. All clinics and surgeries, especially those that rely on digital images, are obliged to keep up with technological advances. It is therefore hoped that our project will become a model for medical structures intending to rationalise digital and other data according to statutory requirements.

  13. Proposal and application of an approach based on AHP and ISO/IEC 25000 to support the evaluation of the quality of project management software systems

    Directory of Open Access Journals (Sweden)

    Matheus Henrique Bartolomeu Marques Morais

    2017-06-01

    Full Text Available In the current competitive scenario, organizations are seeking to improve factors that influence the administration and the success of their projects. The adoption of a project management software suitable to organizational requirements contributes to ensure satisfactory results. In this context, this study proposes a methodology to support the quality evaluation of project management software, which is based on the AHP method (Analytic Hierarchy Process as well as on the criteria and sub-criteria of ISO/IEC 25000. The AHP method is used to define the relevance of the criteria and sub-criteria chosen. The proposed methodology was applied to an illustrative case to select the most appropriate software. The alternatives Basecamp, MS Project, Service Desk and Primavera were evaluated. Primavera and MS Project achieved the higher global performance in the process evaluation, since they fulfill 29 of 30 requirements. However, due to some particularities of the evaluated products, Primavera was selected as being the most suitable.

  14. ATM Quality of Service Tests for Digitized Video Using ATM Over Satellite: Laboratory Tests

    Science.gov (United States)

    Ivancic, William D.; Brooks, David E.; Frantz, Brian D.

    1997-01-01

    A digitized video application was used to help determine minimum quality of service parameters for asynchronous transfer mode (ATM) over satellite. For these tests, binomially distributed and other errors were digitally inserted in an intermediate frequency link via a satellite modem and a commercial gaussian noise generator. In this paper, the relation- ship between the ATM cell error and cell loss parameter specifications is discussed with regard to this application. In addition, the video-encoding algorithms, test configurations, and results are presented in detail.

  15. Enhancing Project-Based Learning in Software Engineering Lab Teaching through an E-Portfolio Approach

    Science.gov (United States)

    Macias, J. A.

    2012-01-01

    Project-based learning is one of the main successful student-centered pedagogies broadly used in computing science courses. However, this approach can be insufficient when dealing with practical subjects that implicitly require many deliverables and a great deal of feedback and organizational resources. In this paper, a worked e-portfolio is…

  16. Design and Development of a User Interface for the Dynamic Model of Software Project Management.

    Science.gov (United States)

    1988-03-01

    rectory of the user’s choice for future...the last choice selected. Let us assume for the sake of this tour that the user has selected all eight choices . ESTIMATED ACTUAL PROJECT SIZE DEFINITION...manipulation of varaibles in the * •. TJin~ca model "h ... ser Inter ace for the Dynamica model was designed b in iterative process of prototyping

  17. Development of Occupational Safety and Health Requirement Management System (OSHREMS Software Using Adobe Dreamweaver CS5 for Building Construction Project

    Directory of Open Access Journals (Sweden)

    Abas Nor Haslinda

    2017-01-01

    Full Text Available The construction industry sector is considered as being risky with frequent and high accident rate. According to Social Security Organization (SOCSO, the construction accidents has arisen from time to time. Construction Industry Development Board (CIDB has developed the Safety and Health Assessment System in Construction (SHASSIC for evaluating the performance of a contractor in construction project by setting out the safety and health management and practices, however the requirement checklist provided is not comprehensive. Therefore, this study aims to develop a software system for facilitating OSH in building construction project, namely OSH requirements management system (OSHREMS, using Adobe Dreamweaver CS5 and Sublime Text as PHP editor. The results from a preliminary study which was conducted through interviews showed that, the respondents were only implementing the basic requirements that comply with legislations, with the absence of appropriate and specific guideline in ensuring occupational safety and health (OSH at the workplace. The tool will be benefits for contractors and other parties to effectively manage the OSH requirements for their projects based on project details.

  18. JULIA: calculation projection software for primary barriers shielding to X-Rays using barite

    International Nuclear Information System (INIS)

    Silva, Júlia R.A.S. da; Vieira, José W.; Lima, Fernando R. A.

    2017-01-01

    The objective was to program a software to calculate the required thicknesses to attenuate X-rays in kilovoltage of 60 kV, 80 kV, 110 kV and 150 kV. The conventional methodological parameters for structural shield calculations established by the NCRP (National Council on Radiation Protection and Measurements) were presented. The descriptive and exploratory methods allowed the construction of the JULIA. In this sense and based on the result obtained, the tool presented is useful for professionals who wish to design structural shielding in radiodiagnostic and/or therapy. The development of calculations in the computational tool corresponds to the accessibility, optimization of time and estimation close to the real. Such heuristic exercise represents improvement of calculations for the estimation of primary barriers with barite

  19. Susceptibility of ATM-deficient pancreatic cancer cells to radiation.

    Science.gov (United States)

    Ayars, Michael; Eshleman, James; Goggins, Michael

    2017-05-19

    Ataxia telangiectasia mutated (ATM) is inactivated in a significant minority of pancreatic ductal adenocarcinomas and may be predictor of treatment response. We determined if ATM deficiency renders pancreatic cancer cells more sensitive to fractionated radiation or commonly used chemotherapeutics. ATM expression was knocked down in three pancreatic cancer cell lines using ATM-targeting shRNA. Isogenic cell lines were tested for sensitivity to several chemotherapeutic agents and radiation. DNA repair kinetics were analyzed in irradiated cells using the comet assay. We find that while rendering pancreatic cancer cells ATM-deficient did not significantly change their sensitivity to several chemotherapeutics, it did render them exquisitely sensitized to radiation. Pancreatic cancer ATM status may help predict response to radiotherapy.

  20. Identification of ATM Protein Kinase Phosphorylation Sites by Mass Spectrometry.

    Science.gov (United States)

    Graham, Mark E; Lavin, Martin F; Kozlov, Sergei V

    2017-01-01

    ATM (ataxia-telangiectasia mutated) protein kinase is a key regulator of cellular responses to DNA damage and oxidative stress. DNA damage triggers complex cascade of signaling events leading to numerous posttranslational modification on multitude of proteins. Understanding the regulation of ATM kinase is therefore critical not only for understanding the human genetic disorder ataxia-telangiectasia and potential treatment strategies, but essential for deciphering physiological responses of cells to stress. These responses play an important role in carcinogenesis, neurodegeneration, and aging. We focus here on the identification of DNA damage inducible ATM phosphorylation sites to understand the importance of autophosphorylation in the mechanism of ATM kinase activation. We demonstrate the utility of using immunoprecipitated ATM in quantitative LC-MS/MS workflow with stable isotope dimethyl labeling of ATM peptides for identification of phosphorylation sites.

  1. Prevalence of deleterious ATM germline mutations in gastric cancer patients.

    Science.gov (United States)

    Huang, Dong-Sheng; Tao, Hou-Quan; He, Xu-Jun; Long, Ming; Yu, Sheng; Xia, Ying-Jie; Wei, Zhang; Xiong, Zikai; Jones, Sian; He, Yiping; Yan, Hai; Wang, Xiaoyue

    2015-12-01

    Besides CDH1, few hereditary gastric cancer predisposition genes have been previously reported. In this study, we discovered two germline ATM mutations (p.Y1203fs and p.N1223S) in a Chinese family with a history of gastric cancer by screening 83 cancer susceptibility genes. Using a published exome sequencing dataset, we found deleterious germline mutations of ATM in 2.7% of 335 gastric cancer patients of different ethnic origins. The frequency of deleterious ATM mutations in gastric cancer patients is significantly higher than that in general population (p=0.0000435), suggesting an association of ATM mutations with gastric cancer predisposition. We also observed biallelic inactivation of ATM in tumors of two gastric cancer patients. Further evaluation of ATM mutations in hereditary gastric cancer will facilitate genetic testing and risk assessment.

  2. ATM-induced radiosensitization in vitro and in vivo

    International Nuclear Information System (INIS)

    Choi, E. K.; Ahn, S. D.; Rhee, Y. H.; Chung, H. S.; Ha, S. W; Song, C. W.; Griffin, R. J.; Park, H. J.

    2003-01-01

    It has been known that ATM plays a central role in response of cells to ionizing radiation by enhancing DNA repair. We have investigated the feasibility of increasing radiosensitivity of tumor cells with the use of ATM inhibitors such as caffeine, pentoxifylline and wortmannin. Human colorectal cancer RKO.C cells and RKO-ATM cells (RKO cells overexpressing ATM) were used in the present study. The clonogenic cell survival in vitro indicated that RKO-ATM cells were markedly radioresistant than RKO.C cells. Treatment with 3 mM of caffeine significantly increased the radiosensitivity of cells, particulary the RKO-ATM cells, so that the radiosensitivity of RKO.C cells and RKO-ATM cells were almost similar. The radiation induced G2/M arrest in RKO-ATM cells was noticeably longer than that in RKO.C cells and caffeine treatment significantly reduced the length of the radiation induced G2/M arrest in both RKO.C and RKO-ATM cells. Pentoxifylline and wortmannin were also less effective than caffeine to radiosensitize RKO.C or RKO-ATM cells. However, wortmannin was more effective than caffeine against human lung adenocarcinoma A549 cells indicating the efficacy of ATM inhibitor to increase radiosensitivity is cell line dependent. For in vivo study, RKO.C cells were injected s.c. into the hind-leg of BALB/c-nuslc nude mice, and allowed to grow to 130mm3 tumor. The mice were i.p. injected with caffeine solution or saline and the tumors irradiated with 10 Gy of X-rays. The radiation induced growth delay was markedly increased by 1-2 mg/g of caffeine. It was concluded that caffeine increases radiosensitivity of tumor cells by inhibiting ATM kinase function, thereby inhibiting DNA repair, that occurs during the G2/M arrest after radiation

  3. Mode of ATM-dependent suppression of chromosome translocation

    Energy Technology Data Exchange (ETDEWEB)

    Yamauchi, Motohiro, E-mail: motoyama@nagasaki-u.ac.jp [Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523 (Japan); Suzuki, Keiji; Oka, Yasuyoshi; Suzuki, Masatoshi; Kondo, Hisayoshi; Yamashita, Shunichi [Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523 (Japan)

    2011-12-09

    Highlights: Black-Right-Pointing-Pointer We addressed how ATM suppresses frequency of chromosome translocation. Black-Right-Pointing-Pointer We found ATM/p53-dependent G1 checkpoint suppresses translocation frequency. Black-Right-Pointing-Pointer We found ATM and DNA-PKcs function in a common pathway to suppress translocation. -- Abstract: It is well documented that deficiency in ataxia telangiectasia mutated (ATM) protein leads to elevated frequency of chromosome translocation, however, it remains poorly understood how ATM suppresses translocation frequency. In the present study, we addressed the mechanism of ATM-dependent suppression of translocation frequency. To know frequency of translocation events in a whole genome at once, we performed centromere/telomere FISH and scored dicentric chromosomes, because dicentric and translocation occur with equal frequency and by identical mechanism. By centromere/telomere FISH analysis, we confirmed that chemical inhibition or RNAi-mediated knockdown of ATM causes 2 to 2.5-fold increase in dicentric frequency at first mitosis after 2 Gy of gamma-irradiation in G0/G1. The FISH analysis revealed that ATM/p53-dependent G1 checkpoint suppresses dicentric frequency, since RNAi-mediated knockdown of p53 elevated dicentric frequency by 1.5-fold. We found ATM also suppresses dicentric occurrence independently of its checkpoint role, as ATM inhibitor showed additional effect on dicentric frequency in the context of p53 depletion and Chk1/2 inactivation. Epistasis analysis using chemical inhibitors revealed that ATM kinase functions in the same pathway that requires kinase activity of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to suppress dicentric frequency. From the results in the present study, we conclude that ATM minimizes translocation frequency through its commitment to G1 checkpoint and DNA double-strand break repair pathway that requires kinase activity of DNA-PKcs.

  4. Hardware and Software Integration in Project Development of Automated Controller System Using LABVIEW FPGA

    International Nuclear Information System (INIS)

    Mohd Khairulezwan Abd Manan; Mohd Sabri Minhat; Izhar Abu Hussin

    2014-01-01

    The Field-Programmable Gate Array (FPGA) is a semiconductor device that can be programmed after manufacturing. Instead of being restricted to any predetermined hardware function, an FPGA allows user to program product features and functions, adapt to new standards, and reconfigure hardware for specific applications even after the product has been installed in the field, hence the name field-programmable. This project developed a control system using LabVIEW FPGA. LabVIEW FPGA is easier where it is programmed by using drag and drop icon. Then it will be integrated with the hardware input and output. (author)

  5. Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction.

    Science.gov (United States)

    Resseguie, Emily A; Staversky, Rhonda J; Brookes, Paul S; O'Reilly, Michael A

    2015-08-01

    High levels of oxygen (hyperoxia) are often used to treat individuals with respiratory distress, yet prolonged hyperoxia causes mitochondrial dysfunction and excessive reactive oxygen species (ROS) that can damage molecules such as DNA. Ataxia telangiectasia mutated (ATM) kinase is activated by nuclear DNA double strand breaks and delays hyperoxia-induced cell death through downstream targets p53 and p21. Evidence for its role in regulating mitochondrial function is emerging, yet it has not been determined if mitochondrial dysfunction or ROS activates ATM. Because ATM maintains mitochondrial homeostasis, we hypothesized that hyperoxia induces both mitochondrial dysfunction and ROS that activate ATM. In A549 lung epithelial cells, hyperoxia decreased mitochondrial respiratory reserve capacity at 12h and basal respiration by 48 h. ROS were significantly increased at 24h, yet mitochondrial DNA double strand breaks were not detected. ATM was not required for activating p53 when mitochondrial respiration was inhibited by chronic exposure to antimycin A. Also, ATM was not further activated by mitochondrial ROS, which were enhanced by depleting manganese superoxide dismutase (SOD2). In contrast, ATM dampened the accumulation of mitochondrial ROS during exposure to hyperoxia. Our findings suggest that hyperoxia-induced mitochondrial dysfunction and ROS do not activate ATM. ATM more likely carries out its canonical response to nuclear DNA damage and may function to attenuate mitochondrial ROS that contribute to oxygen toxicity. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  6. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage

    Science.gov (United States)

    Ortega-Atienza, Sara; Wong, Victor C.; DeLoughery, Zachary; Luczak, Michal W.; Zhitkovich, Anatoly

    2016-01-01

    Many carcinogens damage both DNA and protein constituents of chromatin, and it is unclear how cells respond to this compound injury. We examined activation of the main DNA damage-responsive kinase ATM and formation of DNA double-strand breaks (DSB) by formaldehyde (FA) that forms histone adducts and replication-blocking DNA-protein crosslinks (DPC). We found that low FA doses caused a strong and rapid activation of ATM signaling in human cells, which was ATR-independent and restricted to S-phase. High FA doses inactivated ATM via its covalent dimerization and formation of larger crosslinks. FA-induced ATM signaling showed higher CHK2 phosphorylation but much lower phospho-KAP1 relative to DSB inducers. Replication blockage by DPC did not produce damaged forks or detectable amounts of DSB during the main wave of ATM activation, which did not require MRE11. Chromatin-monitoring KAT5 (Tip60) acetyltransferase was responsible for acetylation and activation of ATM by FA. KAT5 and ATM were equally important for triggering of intra-S-phase checkpoint and ATM signaling promoted recovery of normal human cells after low-dose FA. Our results revealed a major role of the KAT5-ATM axis in protection of replicating chromatin against damage by the endogenous carcinogen FA. PMID:26420831

  7. ATM (ataxia-telangiectasia mutated) abnormality and diseases

    International Nuclear Information System (INIS)

    Takagi, Masatoshi; Nakata, Shinichiro; Mizutani, Shuki

    2007-01-01

    Ataxia-Telangiectasia (A-T) is an autosomal recessive inherited disease due to mutation of ATM gene on chromosome 11q22.3, with major symptoms of ataxia, telangiectasia, immunodeficiency and frequent complication of cancer, and the cells have characters of chromosomal break, high sensitivity to radiation and inappropriate continuation of DNA synthesis after radiation. This review describes past and present studies of ATM functions with clinical features in the following order: Clinical symptoms and epidemiology; ATM gene mutation in A-T patients, mainly by frame-shift (80-90%); ATM, whose gene consisted from 66 exons (150 kb), functions in phosphoinositide-3-kinase related kinase family which protecting cells from stress and integrating their system, at response to DNA double strand break, and in the cell cycle checkpoints at G1/S, S and G2/M phases; ATM nonsense/missense mutations in embryonic cells leading to carcinogenesis and role of ATM in the suppression of carcinogenesis in somatic cells; Chromosomal translocation which relating to carcinogenesis, by functional defect of ATM; and Other functions of ATM in neuronal growth, immunodeficiency, carbohydrate and lipid metabolism, early senescence, and virus infection. ATM is thus an essential molecule to maintain growth and homeostasis. (T.I.)

  8. QUANTUM ESPRESSO: a modular and open-source software project for quantum simulations of materials.

    Science.gov (United States)

    Giannozzi, Paolo; Baroni, Stefano; Bonini, Nicola; Calandra, Matteo; Car, Roberto; Cavazzoni, Carlo; Ceresoli, Davide; Chiarotti, Guido L; Cococcioni, Matteo; Dabo, Ismaila; Dal Corso, Andrea; de Gironcoli, Stefano; Fabris, Stefano; Fratesi, Guido; Gebauer, Ralph; Gerstmann, Uwe; Gougoussis, Christos; Kokalj, Anton; Lazzeri, Michele; Martin-Samos, Layla; Marzari, Nicola; Mauri, Francesco; Mazzarello, Riccardo; Paolini, Stefano; Pasquarello, Alfredo; Paulatto, Lorenzo; Sbraccia, Carlo; Scandolo, Sandro; Sclauzero, Gabriele; Seitsonen, Ari P; Smogunov, Alexander; Umari, Paolo; Wentzcovitch, Renata M

    2009-09-30

    QUANTUM ESPRESSO is an integrated suite of computer codes for electronic-structure calculations and materials modeling, based on density-functional theory, plane waves, and pseudopotentials (norm-conserving, ultrasoft, and projector-augmented wave). The acronym ESPRESSO stands for opEn Source Package for Research in Electronic Structure, Simulation, and Optimization. It is freely available to researchers around the world under the terms of the GNU General Public License. QUANTUM ESPRESSO builds upon newly-restructured electronic-structure codes that have been developed and tested by some of the original authors of novel electronic-structure algorithms and applied in the last twenty years by some of the leading materials modeling groups worldwide. Innovation and efficiency are still its main focus, with special attention paid to massively parallel architectures, and a great effort being devoted to user friendliness. QUANTUM ESPRESSO is evolving towards a distribution of independent and interoperable codes in the spirit of an open-source project, where researchers active in the field of electronic-structure calculations are encouraged to participate in the project by contributing their own codes or by implementing their own ideas into existing codes.

  9. The software life cycle

    CERN Document Server

    Ince, Darrel

    1990-01-01

    The Software Life Cycle deals with the software lifecycle, that is, what exactly happens when software is developed. Topics covered include aspects of software engineering, structured techniques of software development, and software project management. The use of mathematics to design and develop computer systems is also discussed. This book is comprised of 20 chapters divided into four sections and begins with an overview of software engineering and software development, paying particular attention to the birth of software engineering and the introduction of formal methods of software develop

  10. HPC Institutional Computing Project: W15_lesreactiveflow KIVA-hpFE Development: A Robust and Accurate Engine Modeling Software

    Energy Technology Data Exchange (ETDEWEB)

    Carrington, David Bradley [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Waters, Jiajia [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-01-05

    KIVA-hpFE is a high performance computer software for solving the physics of multi-species and multiphase turbulent reactive flow in complex geometries having immersed moving parts. The code is written in Fortran 90/95 and can be used on any computer platform with any popular complier. The code is in two versions, a serial version and a parallel version utilizing MPICH2 type Message Passing Interface (MPI or Intel MPI) for solving distributed domains. The parallel version is at least 30x faster than the serial version and much faster than our previous generation of parallel engine modeling software, by many factors. The 5th generation algorithm construction is a Galerkin type Finite Element Method (FEM) solving conservative momentum, species, and energy transport equations along with two-equation turbulent model k-ω Reynolds Averaged Navier-Stokes (RANS) model and a Vreman type dynamic Large Eddy Simulation (LES) method. The LES method is capable modeling transitional flow from laminar to fully turbulent; therefore, this LES method does not require special hybrid or blending to walls. The FEM projection method also uses a Petrov-Galerkin (P-G) stabilization along with pressure stabilization. We employ hierarchical basis sets, constructed on the fly with enrichment in areas associated with relatively larger error as determined by error estimation methods. In addition, when not using the hp-adaptive module, the code employs Lagrangian basis or shape functions. The shape functions are constructed for hexahedral, prismatic and tetrahedral elements. The software is designed to solve many types of reactive flow problems, from burners to internal combustion engines and turbines. In addition, the formulation allows for direct integration of solid bodies (conjugate heat transfer), as in heat transfer through housings, parts, cylinders. It can also easily be extended to stress modeling of solids, used in fluid structure interactions problems, solidification, porous media

  11. The Perceived Impact of the Agile Development and Project Management Method Scrum on Information Systems and Software Development Productivity

    DEFF Research Database (Denmark)

    Kautz, Karlheinz; Johansen, Thomas Heide; Uldahl, Andreas

    2013-01-01

    This research contributes to the body of knowledge in information systems development (ISD) with an empirical investigation in form of a case study that demonstrates the positive impact of the agile development and project management method Scrum on information systems and software development...... productivity and it provides a useful operationalization of the concept through seven identified indicators for productivity. Despite the fact that the case unit had challenges with the use of Scrum, the indicators identified the areas where the company had managed to exploit the potential of Scrum and its...... practices with regard to increasing productivity. The research results are discussed both with regard to the existing Scrum literature as well as to complex adaptive systems (CAS) as a foundation for ISD and agile development....

  12. The Perceived Impact of the Agile Development and Project Management Method Scrum on Information Systems and Software Development Productivity

    Directory of Open Access Journals (Sweden)

    Karlheinz Kautz

    2014-11-01

    Full Text Available This research contributes to the body of knowledge in information systems development (ISD with an empirical investigation in form of a case study that demonstrates the positive impact of the agile development and project management method Scrum on information systems and software development productivity and it provides a useful operationalization of the concept through seven identified indicators for productivity. Despite the fact that the case unit had challenges with the use of Scrum, the indicators identified the areas where the company had managed to exploit the potential of Scrum and its practices with regard to increasing productivity. The research results are discussed both with regard to the existing Scrum literature as well as to complex adaptive systems (CAS as a foundation for ISD and agile development.

  13. The Alice Project at the IPN, Orsay R and D and software developments 1996-2003

    Energy Technology Data Exchange (ETDEWEB)

    MacCormick, M

    2007-03-15

    This document reviews the theoretical, experimental and technical achievements of the author since the beginning of his scientific career. In 1996 the author became a member of the Alice (A Large heavy Ion Collider Experiment) which was then at the beginning of its research and development phase. The bulk of this report comprises mainly 'snapshots' of the research and development project that was pursued in Orsay for the Alice dimuon arm collaboration. The idea here is to regroup the full set of prototype models, with the technical specifications and their associated test programs. The main results are given for each set of tests, but the details of how data sets were analysed are not included since those details are already available in other, more formal, write-ups. The result is a kind of 'scrapbook' of the research and development phase associated with the Alice dimuon arm station 1 tracker, one of the 5 tracker stations implemented in the dimuon arm spectrometer. This document presented before an academic board will allow its author to manage research works and particularly to tutor thesis students.

  14. The Alice Project at the IPN, Orsay R and D and software developments 1996-2003

    Energy Technology Data Exchange (ETDEWEB)

    MacCormick, M

    2007-03-15

    This document reviews the theoretical, experimental and technical achievements of the author since the beginning of his scientific career. In 1996 the author became a member of the Alice (A Large heavy Ion Collider Experiment) which was then at the beginning of its research and development phase. The bulk of this report comprises mainly 'snapshots' of the research and development project that was pursued in Orsay for the Alice dimuon arm collaboration. The idea here is to regroup the full set of prototype models, with the technical specifications and their associated test programs. The main results are given for each set of tests, but the details of how data sets were analysed are not included since those details are already available in other, more formal, write-ups. The result is a kind of 'scrapbook' of the research and development phase associated with the Alice dimuon arm station 1 tracker, one of the 5 tracker stations implemented in the dimuon arm spectrometer. This document presented before an academic board will allow its author to manage research works and particularly to tutor thesis students.

  15. The Alice Project at the IPN, Orsay R and D and software developments 1996-2003

    International Nuclear Information System (INIS)

    MacCormick, M.

    2007-03-01

    This document reviews the theoretical, experimental and technical achievements of the author since the beginning of his scientific career. In 1996 the author became a member of the Alice (A Large heavy Ion Collider Experiment) which was then at the beginning of its research and development phase. The bulk of this report comprises mainly 'snapshots' of the research and development project that was pursued in Orsay for the Alice dimuon arm collaboration. The idea here is to regroup the full set of prototype models, with the technical specifications and their associated test programs. The main results are given for each set of tests, but the details of how data sets were analysed are not included since those details are already available in other, more formal, write-ups. The result is a kind of 'scrapbook' of the research and development phase associated with the Alice dimuon arm station 1 tracker, one of the 5 tracker stations implemented in the dimuon arm spectrometer. This document presented before an academic board will allow its author to manage research works and particularly to tutor thesis students

  16. Customer Interaction in Software Development: A Comparison of Software Methodologies Deployed in Namibian Software Firms

    CSIR Research Space (South Africa)

    Iyawa, GE

    2016-01-01

    Full Text Available within the Namibian context. An implication for software project managers and software developers is that customer interaction should be properly managed to ensure that the software methodologies for improving software development processes...

  17. A Requirements-Based Exploration of Open-Source Software Development Projects--Towards a Natural Language Processing Software Analysis Framework

    Science.gov (United States)

    Vlas, Radu Eduard

    2012-01-01

    Open source projects do have requirements; they are, however, mostly informal, text descriptions found in requests, forums, and other correspondence. Understanding such requirements provides insight into the nature of open source projects. Unfortunately, manual analysis of natural language requirements is time-consuming, and for large projects,…

  18. ATM LAN Emulation: Getting from Here to There.

    Science.gov (United States)

    Learn, Larry L., Ed.

    1995-01-01

    Discusses current LAN (local area network) configuration and explains ATM (asynchronous transfer mode) as the future telecommunications transport. Highlights include LAN emulation, which enables the interconnection of legacy LANs and the new ATM environment; virtual LANs; broadcast servers; and standards. (LRW)

  19. ATM Tactical Network - a challenge for the military networks

    NARCIS (Netherlands)

    Waveren, C.J. van; Luiijf, H.A.M.; Burakowski, W.; Kopertowski, Z.

    1997-01-01

    The next generation of tactical networks will be based on the ATM technology. The POST-2000 tactical network is just in the designing phase. The objective of this paper is to point out the main problems which should be solved to adopt ATM technology into the tactical network environment. The

  20. Enhancing the Current Automated Teller Machine (ATM) in Nigerian ...

    African Journals Online (AJOL)

    This is going to be achieved by creating another input device that collects the money into the ATM system, reads its denomination and either saves it or transfers it the required customer ... Keywords: Automated Teller Machine (ATM), Interswitch, Local Area Network (LAN), Wide Area Network (WAN), Telecommunication.

  1. ATM: The Key To Harnessing the Power of Networked Multimedia.

    Science.gov (United States)

    Gross, Rod

    1996-01-01

    ATM (Asynchronous Transfer Mode) network technology handles the real-time continuous traffic flow necessary to support desktop multimedia applications. Describes network applications already used: desktop video collaboration, distance learning, and broadcasting video delivery. Examines the architecture of ATM technology, video delivery and sound…

  2. ATM Technology Adoption in U.S. Campus Networking.

    Science.gov (United States)

    Yao, Engui; Perry, John F.; Anderson, Larry S.; Brook, R. Dan; Hare, R. Dwight; Moore, Arnold J.; Xu, Xiaohe

    This study examined the relationships between ATM (asynchronous transfer mode) adoption in universities and four organizational variables: university size, type, finances, and information processing maturity. Another purpose of the study was to identify the current status of ATM adoption in campus networking. Subjects were university domain LAN…

  3. ATM, radiation, and the risk of second primary breast cancer.

    Science.gov (United States)

    Bernstein, Jonine L; Concannon, Patrick

    2017-10-01

    It was first suggested more than 40 years ago that heterozygous carriers for the human autosomal recessive disorder Ataxia-Telangiectasia (A-T) might also be at increased risk for cancer. Subsequent studies have identified the responsible gene, Ataxia-Telangiectasia Mutated (ATM), characterized genetic variation at this locus in A-T and a variety of different cancers, and described the functions of the ATM protein with regard to cellular DNA damage responses. However, an overall model of how ATM contributes to cancer risk, and in particular, the role of DNA damage in this process, remains lacking. This review considers these questions in the context of contralateral breast cancer (CBC). Heterozygous carriers of loss of function mutations in ATM that are A-T causing, are at increased risk of breast cancer. However, examination of a range of genetic variants, both rare and common, across multiple cancers, suggests that ATM may have additional effects on cancer risk that are allele-dependent. In the case of CBC, selected common alleles at ATM are associated with a reduced incidence of CBC, while other rare and predicted deleterious variants may act jointly with radiation exposure to increase risk. Further studies that characterize germline and somatic ATM mutations in breast cancer and relate the detected genetic changes to functional outcomes, particularly with regard to radiation responses, are needed to gain a complete picture of the complex relationship between ATM, radiation and breast cancer.

  4. Software engineering architecture-driven software development

    CERN Document Server

    Schmidt, Richard F

    2013-01-01

    Software Engineering: Architecture-driven Software Development is the first comprehensive guide to the underlying skills embodied in the IEEE's Software Engineering Body of Knowledge (SWEBOK) standard. Standards expert Richard Schmidt explains the traditional software engineering practices recognized for developing projects for government or corporate systems. Software engineering education often lacks standardization, with many institutions focusing on implementation rather than design as it impacts product architecture. Many graduates join the workforce with incomplete skil

  5. Models for setting ATM parameter values

    DEFF Research Database (Denmark)

    Blaabjerg, Søren; Gravey, A.; Romæuf, L.

    1996-01-01

    essential to set traffic characteristic values that are relevant to the considered cell stream, and that ensure that the amount of non-conforming traffic is small. Using a queueing model representation for the GCRA formalism, several methods are available for choosing the traffic characteristics. This paper......In ATM networks, a user should negotiate at connection set-up a traffic contract which includes traffic characteristics and requested QoS. The traffic characteristics currently considered are the Peak Cell Rate, the Sustainable Cell Rate, the Intrinsic Burst Tolerance and the Cell Delay Variation...... (CDV) tolerance(s). The values taken by these traffic parameters characterize the so-called ''Worst Case Traffic'' that is used by CAC procedures for accepting a new connection and allocating resources to it. Conformance to the negotiated traffic characteristics is defined, at the ingress User...

  6. Parametric analysis of ATM solar array.

    Science.gov (United States)

    Singh, B. K.; Adkisson, W. B.

    1973-01-01

    The paper discusses the methods used for the calculation of ATM solar array performance characteristics and provides the parametric analysis of solar panels used in SKYLAB. To predict the solar array performance under conditions other than test conditions, a mathematical model has been developed. Four computer programs have been used to convert the solar simulator test data to the parametric curves. The first performs module summations, the second determines average solar cell characteristics which will cause a mathematical model to generate a curve matching the test data, the third is a polynomial fit program which determines the polynomial equations for the solar cell characteristics versus temperature, and the fourth program uses the polynomial coefficients generated by the polynomial curve fit program to generate the parametric data.

  7. ATM-induced radiosensitization in vitro and in vivo

    International Nuclear Information System (INIS)

    Song, C. W.; Griffin, R. J.; Park, H. J.; Chung, H. S.; Choi, E. K.; Ahn, S. D.; Rhee, Y. H.; Ha, S. W.

    2002-01-01

    It has been known that ATM plays a central role in response of cells to ionizing radiation by enhancing DNA repair. Based in large part on studies of the homologous proteins in yeast, it is predicted that ATM function as proximal signal transducers in G1, S, and G2 checkpoint pathways. With the exception of p53, the downstream components of these pathways remain largely undefined. We have investigated the feasibility of increasing radiosensitivity of tumor cells with the use of ATM inhibitors such as caffeine, pentoxifylline, and wortmannin. Also in an effort to examine and understand the molecular mechanism by which ATM might exert its cellular effects, we have expressed the full length wild type ATM in RKO cells

  8. Telemedicine with integrated data security in ATM-based networks

    Science.gov (United States)

    Thiel, Andreas; Bernarding, Johannes; Kurth, Ralf; Wenzel, Rudiger; Villringer, Arno; Tolxdorff, Thomas

    1997-05-01

    Telemedical services rely on the digital transfer of large amounts of data in a short time. The acceptance of these services requires therefore new hard- and software concepts. The fast exchange of data is well performed within a high- speed ATM-based network. The fast access to the data from different platforms imposes more difficult problems, which may be divided into those relating to standardized data formats and those relating to different levels of data security across nations. For a standardized access to the formats and those relating to different levels of data security across nations. For a standardized access to the image data, a DICOM 3.0 server was implemented.IMages were converted into the DICOM 3.0 standard if necessary. The access to the server is provided by an implementation of DICOM in JAVA allowing access to the data from different platforms. Data protection measures to ensure the secure transfer of sensitive patient data are not yet solved within the DICOM concept. We investigated different schemes to protect data using the DICOM/JAVA modality with as little impact on data transfer speed as possible.

  9. A Phenomenological Inquiry into the Perceptions of Software Professionals on the Asperger's Syndrome/High Functioning Autism Spectrum and the Success of Software Development Projects

    Science.gov (United States)

    Kendall, Leslie R.

    2013-01-01

    Individuals who have Asperger's Syndrome/High-Functioning Autism, as a group, are chronically underemployed and underutilized. Many in this group have abilities that are well suited for various roles within the practice of software development. Multiple studies have shown that certain organizational and management changes in the software…

  10. ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration

    Czech Academy of Sciences Publication Activity Database

    Jaiswal, H.; Benada, Jan; Müllers, E.; Akopyan, K.; Burdová, Kamila; Koolmeister, T.; Helleday, T.; Medema, R.H.; Macůrek, Libor; Lindqvist, A.

    2017-01-01

    Roč. 36, č. 14 (2017), s. 2161-2176 ISSN 0261-4189 R&D Projects: GA ČR GA13-18392S Institutional support: RVO:68378050 Keywords : ATM * ATR * checkpoint recovery * G2 * Pik1 Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Cell biology Impact factor: 9.792, year: 2016

  11. Molecular Cloning Designer Simulator (MCDS: All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects

    Directory of Open Access Journals (Sweden)

    Zhenyu Shi

    2016-12-01

    Full Text Available Molecular Cloning Designer Simulator (MCDS is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects. In addition to standard functions, it has a number of features that are either unique, or are not found in combination in any one software package: (1 it has a novel interactive flow-chart user interface for complex multi-step processes, allowing an integrated overview of the whole project; (2 it can perform a user-defined workflow of cloning steps in a single execution of the software; (3 it can handle multiple types of genetic recombineering, a technique that is rapidly replacing classical cloning for many applications; (4 it includes experimental information to conveniently guide wet lab work; and (5 it can store results and comments to allow the tracking and management of the whole project in one platform. MCDS is freely available from https://mcds.codeplex.com. Keywords: BioCAD, Genetic engineering software, Molecular cloning software, Synthetic biology, Workflow simulation and management

  12. Interconnection of Broadband Islands via Satellite-Experiments on the Race II Catalyst Project

    National Research Council Canada - National Science Library

    Sun, Z

    1996-01-01

    .... The purpose of the project was to develop an ATM satellite link for the future B-ISDN services, particularly for the interconnections of the ATM testbeds which are in the form of broadband islands...

  13. Scenarios for control and data flows in multiprotocol over ATM

    Science.gov (United States)

    Kujoory, Ali

    1997-10-01

    The multiprotocol over ATM (MPOA), specified by the ATM Forum, provides an architecture for transfer of Internetwork layer packets (Layer 3 datagram such as IP, IPX) over ATM subnets or across the emulated LANs. MPOA provides shortcuts that bypass routers to avoid router bottlenecks. It is a grand union of some of the existing standards such as LANE by the ATM Forum, NHRP by the IETF, and the Q.2931 by ITU. The intent of this paper is to clarify the data flows between pairs of source and destination hosts in an MPOA system. It includes scenarios for both the intra- and inter-subnet flows between different pairs of MPOA end-systems. The intrasubnet flows simply use LANE for address resolution or data transfer. The inter-subnet flows may use a default path for short-lived flows or a shortcut for long-lived flows. The default path uses the LANE and router capabilities. The shortcut path uses LANE plus NHRP for ATM address resoluton. An ATM virtual circuit is established before the data transfer. This allows efficient transfer of internetwork layer packets over ATM for real-time applications.

  14. Structure of the intact ATM/Tel1 kinase

    Science.gov (United States)

    Wang, Xuejuan; Chu, Huanyu; Lv, Mengjuan; Zhang, Zhihui; Qiu, Shuwan; Liu, Haiyan; Shen, Xuetong; Wang, Weiwu; Cai, Gang

    2016-05-01

    The ataxia-telangiectasia mutated (ATM) protein is an apical kinase that orchestrates the multifaceted DNA-damage response. Normally, ATM kinase is in an inactive, homodimer form and is transformed into monomers upon activation. Besides a conserved kinase domain at the C terminus, ATM contains three other structural modules, referred to as FAT, FATC and N-terminal helical solenoid. Here we report the first cryo-EM structure of ATM kinase, which is an intact homodimeric ATM/Tel1 from Schizosaccharomyces pombe. We show that two monomers directly contact head-to-head through the FAT and kinase domains. The tandem N-terminal helical solenoid tightly packs against the FAT and kinase domains. The structure suggests that ATM/Tel1 dimer interface and the consecutive HEAT repeats inhibit the binding of kinase substrates and regulators by steric hindrance. Our study provides a structural framework for understanding the mechanisms of ATM/Tel1 regulation as well as the development of new therapeutic agents.

  15. Commercial Literacy Software.

    Science.gov (United States)

    Balajthy, Ernest

    1997-01-01

    Presents the first year's results of a continuing project to monitor the availability of software of relevance for literacy education purposes. Concludes there is an enormous amount of software available for use by teachers of reading and literacy--whereas drill-and-practice software is the largest category of software available, large numbers of…

  16. MPLS y ATM como tecnologías backbone para la transferencia de videoconferencia

    Directory of Open Access Journals (Sweden)

    Danilo López

    2012-09-01

    Full Text Available This article presents the results obtained by modeling the performance of a core IP/ATM network compared to a CRLDP/IP/MPLS network when carrying delay sensitive traffic (videoconferencing with minimum resource reservation guarantees and optimal interaction between user and applications. In order conduct the experiments, OPNET-modeler simulation software (educational version was used, which encouraged alternative implementation features that help decide which of the two technologies represents a suitable solution for current networking problems, where large volumes of information need to be transmitted and the QoS offered to average users is pretty poor.

  17. ARC Software and Models

    Science.gov (United States)

    Archives RESEARCH ▼ Research Areas Ongoing Projects Completed Projects SOFTWARE CONTACT ▼ Primary Contacts Researchers External Link MLibrary Deep Blue Software Archive Most research conducted at the ARC produce software code and methodologies that are transferred to TARDEC and industry partners. These

  18. Accelerating Software Development through Agile Practices--A Case Study of a Small-Scale, Time-Intensive Web Development Project at a College-Level IT Competition

    Science.gov (United States)

    Zhang, Xuesong; Dorn, Bradley

    2012-01-01

    Agile development has received increasing interest both in industry and academia due to its benefits in developing software quickly, meeting customer needs, and keeping pace with the rapidly changing requirements. However, agile practices and scrum in particular have been mainly tested in mid- to large-size projects. In this paper, we present…

  19. D-ATM, a working example of health care interoperability: From dirt path to gravel road.

    Science.gov (United States)

    DeClaris, John-William

    2009-01-01

    For many years, there have been calls for interoperability within health care systems. The technology currently exists and is being used in business areas like banking and commerce, to name a few. Yet the question remains, why has interoperability not been achieved in health care? This paper examines issues encountered and success achieved with interoperability during the development of the Digital Access To Medication (D-ATM) project, sponsored by the Substance Abuse and Mental Health Services Administration (SAMHSA). D-ATM is the first government funded interoperable patient management system. The goal of this paper is to provide lessons learned and propose one possible road map for health care interoperability within private industry and how government can help.

  20. Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity

    International Nuclear Information System (INIS)

    Roy, Kanaklata; Wang, Lilin; Makrigiorgos, G. Mike; Price, Brendan D.

    2006-01-01

    Glioblastomas are among the malignancies most resistant to radiation therapy. In contrast, cells lacking the ATM protein are highly sensitive to ionizing radiation. The relationship between ATM protein expression and radiosensitivity in 3 glioma cell lines was examined. T98G cells exhibited normal levels of ATM protein, whereas U118 and U87 cells had significantly lower levels of ATM and increased (>2-fold) sensitivity to ionizing radiation compared to T98G cells. The ATM promoter was methylated in U87 cells. Demethylation by azacytidine treatment increased ATM protein levels in the U87 cells and decreased their radiosensitivity. In contrast, the ATM promoter in U118 cells was not methylated. Further, expression of exogenous ATM did not significantly alter the radiosensitivity of U118 cells. ATM expression is therefore heterogeneous in the glioma cells examined. In conclusion, methylation of the ATM promoter may account for the variable radiosensitivity and heterogeneous ATM expression in a fraction of glioma cells

  1. 3rd ENRI International Workshop on ATM/CNS

    CERN Document Server

    2014-01-01

    The Electronic Navigation Research Institute (ENRI) held its third International Workshop on ATM / CNS in 2013 with the theme of "Drafting the future sky". There is worldwide activity taking place in the research and development of modern air traffic management (ATM) and its enabling technologies in Communication, Navigation and Surveillance (CNS). Pioneering work is necessary to contribute to the global harmonization of air traffic management and control. At this workshop, leading experts in  research, industry and academia from around the world met to share their ideas and approaches on ATM/CNS related topics.

  2. ATM localization and gene expression in the adult mouse eye.

    Science.gov (United States)

    Leemput, Julia; Masson, Christel; Bigot, Karine; Errachid, Abdelmounaim; Dansault, Anouk; Provost, Alexandra; Gadin, Stéphanie; Aoufouchi, Said; Menasche, Maurice; Abitbol, Marc

    2009-01-01

    High levels of metabolism and oxygen consumption in most adult murine ocular compartments, combined with exposure to light and ultraviolet (UV) radiation, are major sources of oxidative stress, causing DNA damage in ocular cells. Of all mammalian body cells, photoreceptor cells consume the largest amount of oxygen and generate the highest levels of oxidative damage. The accumulation of such damage throughout life is a major factor of aging tissues. Several multiprotein complexes have recently been identified as the major sensors and mediators involved in the maintenance of DNA integrity. The activity of these complexes initially seemed to be restricted to dividing cells, given their ultimate role in major cell cycle checkpoints. However, it was later established that they are also active in post-mitotic cells. Recent findings demonstrate that the DNA damage response (DDR) is essential for the development, maintenance, and normal functioning of the adult central nervous system. One major molecular factor in the DDR is the protein, ataxia telangiectasia mutated (ATM). It is required for the rapid induction of cellular responses to DNA double-strand breaks. These cytotoxic DNA lesions may be caused by oxidative damage. To understand how ATM prevents oxidative stress and participates in the maintenance of genomic integrity and cell viability of the adult retina, we determined the ATM expression patterns and studied its localization in the adult mouse eye. Atm gene expression was analyzed by RT-PCR experiments and its localization by in situ hybridization on adult mouse ocular and cerebellar tissue sections. ATM protein expression was determined by western blot analysis of proteins homogenates extracted from several mouse tissues and its localization by immunohistochemistry experiments performed on adult mouse ocular and cerebellar tissue sections. In addition, subcellular localization was realized by confocal microscopy imaging of ocular tissue sections, with a special

  3. Independent Verification and Validation Of SAPHIRE 8 Software Requirements Project Number: N6423 U.S. Nuclear Regulatory Commission

    Energy Technology Data Exchange (ETDEWEB)

    Kent Norris

    2009-09-01

    The purpose of the Independent Verification and Validation (IV&V) role in the evaluation of the SAPHIRE requirements definition is to assess the activities that results in the specification, documentation, and review of the requirements that the software product must satisfy, including functionality, performance, design constraints, attributes and external interfaces. The IV&V team began this endeavor after the software engineering and software development of SAPHIRE had already been in production. IV&V reviewed the requirements specified in the NRC Form 189s to verify these requirements were included in SAPHIRE’s Software Verification and Validation Plan (SVVP).

  4. Knowledge Base for an Intelligent System in order to Identify Security Requirements for Government Agencies Software Projects

    Directory of Open Access Journals (Sweden)

    Adán Beltrán G.

    2016-01-01

    Full Text Available It has been evidenced that one of the most common causes in the failure of software security is the lack of identification and specification of requirements for information security, it is an activity with an insufficient importance in the software development or software acquisition We propose the knowledge base of CIBERREQ. CIBERREQ is an intelligent knowledge-based system used for the identification and specification of security requirements in the software development cycle or in the software acquisition. CIBERREQ receives functional software requirements written in natural language and produces non-functional security requirements through a semi-automatic process of risk management. The knowledge base built is formed by an ontology developed collaboratively by experts in information security. In this process has been identified six types of assets: electronic data, physical data, hardware, software, person and service; as well as six types of risk: competitive disadvantage, loss of credibility, economic risks, strategic risks, operational risks and legal sanctions. In addition there are defined 95 vulnerabilities, 24 threats, 230 controls, and 515 associations between concepts. Additionally, automatic expansion was used with Wikipedia for the asset types Software and Hardware, obtaining 7125 and 5894 software and hardware subtypes respectively, achieving thereby an improvement of 10% in the identification of the information assets candidates, one of the most important phases of the proposed system.

  5. NASA's ATM Technology Demonstration-1: Integrated Concept of Arrival Operations

    Science.gov (United States)

    Baxley, Brian T.; Swenson, Harry N.; Prevot, Thomas; Callantine, Todd J.

    2012-01-01

    This paper describes operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) demonstration will integrate three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to touchdown. It also enables aircraft to conduct Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and implantation into an operational environment. Goals of the ATD-1 demonstration include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.

  6. An HTRF® Assay for the Protein Kinase ATM.

    Science.gov (United States)

    Adams, Phillip; Clark, Jonathan; Hawdon, Simon; Hill, Jennifer; Plater, Andrew

    2017-01-01

    Ataxia telangiectasia mutated (ATM) is a serine/threonine kinase that plays a key role in the regulation of DNA damage pathways and checkpoint arrest. In recent years, there has been growing interest in ATM as a therapeutic target due to its association with cancer cell survival following genotoxic stress such as radio- and chemotherapy. Large-scale targeted drug screening campaigns have been hampered, however, by technical issues associated with the production of sufficient quantities of purified ATM and the availability of a suitable high-throughput assay. Using a purified, functionally active recombinant ATM and one of its physiological substrates, p53, we have developed an in vitro FRET-based activity assay that is suitable for high-throughput drug screening.

  7. Cost-benefit analysis of the ATM automatic deposit service

    Directory of Open Access Journals (Sweden)

    Ivica Županović

    2015-03-01

    Full Text Available Bankers and other financial experts have analyzed the value of automated teller machines (ATM in terms of growing consumer demand, rising costs of technology development, decreasing profitability and market share. This paper presents a step-by-step cost-benefit analysis of the ATM automatic deposit service. The first step is to determine user attitudes towards using ATM automatic deposit service by using the Technology Acceptance Model (TAM. The second step is to determine location priorities for ATMs that provide automatic deposit services using the Analytic Hierarchy Process (AHP model. The results of the previous steps enable a highly efficient application of cost-benefit analysis for evaluating costs and benefits of automatic deposit services. To understand fully the proposed procedure outside of theoretical terms, a real-world application of a case study is conducted.

  8. Method of ATMS operators in the formalism of Faddeev equations

    International Nuclear Information System (INIS)

    Zubarev, D.A.

    1991-01-01

    The method of ATMS operators is generalized for the case of Faddeev equations. The method to construct effective equations for both elastic scattering and scattering with rearrangement is presented. Properties to obtained equations are considered

  9. 4th ENRI International Workshop on ATM/CNS

    CERN Document Server

    2017-01-01

    This book is a compilation of selected papers from the 4th ENRI International Workshop on ATM/CNS (EIWAC2015). The work focuses on novel techniques for aviation infrastructure in air traffic management (ATM) and communications, navigation, surveillance, and informatics (CNSI) domains. The contents make valuable contributions to academic researchers, engineers in the industry, and regulators of aviation authorities. As well, readers will encounter new ideas for realizing a more efficient and safer aviation system. .

  10. A survey on the status of ATM based LAN

    International Nuclear Information System (INIS)

    Yang, Sung Woon; Kang, Soon Ju

    1996-03-01

    This report presents the technical status of the ATM(Asynchronous Transfer Mode) as a new high speed data communication method. Since the FDDI(Fiber optic Distributed Data Interchange) backbone has been installed in september 1995, it has been used as a main network structure of KAERI. However, recently high speed and multimedia data communication environment is being required to accommodate the recent trend of the network usage in KAERI. For example, the rapid growth of Internet usage and increased activities of information retrieval systems on KAERI-Net demand more effective network system. Chapter 1 discusses the status of KAERI-Net and the selection criteria of a network model according to the national plan of super high speed network structure. In Chapter 2, the basic concept of ATM such as communication method and communication structure is studied, and Chapter 3 presents the overall concepts of standard model of ATM. In Chapter 4, we survey the recent trend of technical development of ATM and analyze the status of ATM technology. As a concluding remark, Chapter 5 discusses the criteria and check points for optimal design of KAERI-Net backbone. This report will be used as a technical reference for the installation of ATM in KAERI-Net. 10 tabs., 32 figs., 11 refs. (Author)

  11. Quantitative and Dynamic Imaging of ATM Kinase Activity.

    Science.gov (United States)

    Nyati, Shyam; Young, Grant; Ross, Brian Dale; Rehemtulla, Alnawaz

    2017-01-01

    Ataxia telangiectasia mutated (ATM) is a serine/threonine kinase critical to the cellular DNA-damage response, including DNA double-strand breaks (DSBs). ATM activation results in the initiation of a complex cascade of events facilitating DNA damage repair, cell cycle checkpoint control, and survival. Traditionally, protein kinases have been analyzed in vitro using biochemical methods (kinase assays using purified proteins or immunological assays) requiring a large number of cells and cell lysis. Genetically encoded biosensors based on optical molecular imaging such as fluorescence or bioluminescence have been developed to enable interrogation of kinase activities in live cells with a high signal to background. We have genetically engineered a hybrid protein whose bioluminescent activity is dependent on the ATM-mediated phosphorylation of a substrate. The engineered protein consists of the split luciferase-based protein complementation pair with a CHK2 (a substrate for ATM kinase activity) target sequence and a phospho-serine/threonine-binding domain, FHA2, derived from yeast Rad53. Phosphorylation of the serine residue within the target sequence by ATM would lead to its interaction with the phospho-serine-binding domain, thereby preventing complementation of the split luciferase pair and loss of reporter activity. Bioluminescence imaging of reporter expressing cells in cultured plates or as mouse xenografts provides a quantitative surrogate for ATM kinase activity and therefore the cellular DNA damage response in a noninvasive, dynamic fashion.

  12. ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity

    International Nuclear Information System (INIS)

    Boohaker, Rebecca J.; Cui, Xiaoli; Stackhouse, Murray; Xu, Bo

    2013-01-01

    Purpose: Activation of the DNA damage responsive protein kinase ATM is a critical step for cellular survival in response to ionizing irradiation (IR). Direct targets of ATM regulating radiosensitivity remain to be fully investigated. We have recently reported that ATM phosphorylates the transcriptional repressor Snail on Serine 100. We aimed to further study the functional significance of ATM-mediated Snail phosphorylation in response to IR. Material and methods: We transfected vector-only, wild-type, the Serine 100 to alanine (S100A) or to glutamic acid (S100E) substitution of Snail into various cell lines. We assessed colony formation, γ-H2AX focus formation and the invasion index in the cells treated with or without IR. Results: We found that over-expression of the S100A mutant Snail in HeLa cells significantly increased radiosensitivity. Meanwhile the expression of S100E, a phospho-mimicking mutation, resulted in enhanced radio-resistance. Interestingly, S100E could rescue the radiosensitive phenotype in ATM-deficient cells. We also found that expression of S100E increased γ-H2AX focus formation and compromised inhibition of invasion in response to IR independent of cell survival. Conclusion: ATM-mediated Snail Serine 100 phosphorylation in response to IR plays an important part in the regulation of radiosensitivity

  13. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion.

    Science.gov (United States)

    Chen, Wei-Ta; Ebelt, Nancy D; Stracker, Travis H; Xhemalce, Blerta; Van Den Berg, Carla L; Miller, Kyle M

    2015-06-01

    Ataxia-telangiectasia mutated (ATM) protein kinase regulates the DNA damage response (DDR) and is associated with cancer suppression. Here we report a cancer-promoting role for ATM. ATM depletion in metastatic cancer cells reduced cell migration and invasion. Transcription analyses identified a gene network, including the chemokine IL-8, regulated by ATM. IL-8 expression required ATM and was regulated by oxidative stress. IL-8 was validated as an ATM target by its ability to rescue cell migration and invasion defects in ATM-depleted cells. Finally, ATM-depletion in human breast cancer cells reduced lung tumors in a mouse xenograft model and clinical data validated IL-8 in lung metastasis. These findings provide insights into how ATM activation by oxidative stress regulates IL-8 to sustain cell migration and invasion in cancer cells to promote metastatic potential. Thus, in addition to well-established roles in tumor suppression, these findings identify a role for ATM in tumor progression.

  14. ATM Coastal Topography-Louisiana, 2001: UTM Zone 15 (Part 1 of 2)

    Science.gov (United States)

    Yates, Xan; Nayegandhi, Amar; Brock, John C.; Sallenger, A.H.; Klipp, Emily S.; Wright, C. Wayne

    2010-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived first-surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of a portion of the Louisiana coastline beach face within UTM Zone 15, from Isles Dernieres to Grand Isle, acquired September 7 and 10, 2001. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative scanning lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last

  15. ATM Coastal Topography - Louisiana, 2001: UTM Zone 16 (Part 2 of 2)

    Science.gov (United States)

    Yates, Xan; Nayegandhi, Amar; Brock, John C.; Sallenger, Asbury H.; Klipp, Emily S.; Wright, C. Wayne

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived first-surface (FS) topography were produced collaboratively by the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of a portion of the Louisiana coastline beach face within UTM Zone 16, from Grand Isle to the Chandeleur Islands, acquired September 7 and 9, 2001. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative scanning lidar instrument originally developed by NASA, and known as the Airborne Topographic Mapper (ATM), was used during data acquisition. The ATM system is a scanning lidar system that measures high-resolution topography of the land surface and incorporates a green-wavelength laser operating at pulse rates of 2 to 10 kilohertz. Measurements from the laser-ranging device are coupled with data acquired from inertial navigation system (INS) attitude sensors and differentially corrected global positioning system (GPS) receivers to measure topography of the surface at accuracies of +/-15 centimeters. The nominal ATM platform is a Twin Otter or P-3 Orion aircraft, but the instrument may be deployed on a range of light aircraft. Elevation measurements were collected over the survey area using the ATM system, and the resulting data were then processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and

  16. A retrospective critic Re-Debate on Stakeholders’ resistance checklist in software project management within multi-cultural, multi-ethnical and cosmopolitan society context: The Malaysian experience

    Directory of Open Access Journals (Sweden)

    Hamed Taherdoost

    2016-12-01

    Full Text Available Risks stemming from software projects were extensively studied. However, software project risk management has rarely researched organizational risks within multi-cultural and multi-ethnical atmospheres. The fact of the matter is that problems occur when the stakeholders’ cultural and ethnical aspects are not addressed, especially in multi-cultural, multi-ethnical, and cosmopolitan society such as Malaysia. To avoid analyzing something that has already been studied in detail, this study conducted based on in-depth literature review considering key word search in subject-specific databases. Journal articles published in reputed journals were reviewed. By employing Rumelt’s resistance to change checklist and culture gap tool source, this paper develops an organizational risk framework considering cross-cultural and cross-ethnical critical factors in order to show how can risks be better comprehended and managed. The significance of bio-cultural dimensions was scrutinized as vital criteria which should be considered in international project sphere, so that, not only the odds of project success would be increased but also the risks can be mitigated significantly. A review of the risk management process, Rumelt’s Checklist, cultural issues in international project environment allows a better understanding of the importance of cultural dimensions in project spheres.

  17. Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts.

    Science.gov (United States)

    Sun, Chuan; Wei, Xiaoxia; Fei, Yue; Su, Liling; Zhao, Xinyuan; Chen, Guangdi; Xu, Zhengping

    2016-11-18

    Radiofrequency electromagnetic fields (RF-EMFs) have been classified by the International Agency for Research on Cancer as possible carcinogens to humans; however, this conclusion is based on limited epidemiological findings and lacks solid support from experimental studies. In particular, there are no consistent data regarding the genotoxicity of RF-EMFs. Ataxia telangiectasia mutated (ATM) is recognised as a chief guardian of genomic stability. To address the debate on whether RF-EMFs are genotoxic, we compared the effects of 1,800 MHz RF-EMF exposure on genomic DNA in mouse embryonic fibroblasts (MEFs) with proficient (Atm +/+ ) or deficient (Atm -/- ) ATM. In Atm +/+ MEFs, RF-EMF exposure for 1 h at an average special absorption rate of 4.0 W/kg induced significant DNA single-strand breaks (SSBs) and activated the SSB repair mechanism. This effect reduced the DNA damage to less than that of the background level after 36 hours of exposure. In the Atm -/- MEFs, the same RF-EMF exposure for 12 h induced both SSBs and double-strand breaks and activated the two repair processes, which also reduced the DNA damage to less than the control level after prolonged exposure. The observed phenomenon is similar to the hormesis of a toxic substance at a low dose. To the best of our knowledge, this study is the first to report a hormesis-like effect of an RF-EMF.

  18. Caltrans WeatherShare Phase II System: An Application of Systems and Software Engineering Process to Project Development

    Science.gov (United States)

    2009-08-25

    In cooperation with the California Department of Transportation, Montana State University's Western Transportation Institute has developed the WeatherShare Phase II system by applying Systems Engineering and Software Engineering processes. The system...

  19. The Generalizability of Private Sector Research on Software Project Management in Two USAF Organizations: An Exploratory Study

    National Research Council Canada - National Science Library

    Garman, Michael

    2003-01-01

    .... But most of this research in peer reviewed journals has focused on the private sector. Researchers have also identified software acquisitions as one of the major differences between the private sector and public sector MIS...

  20. Application of Metric-based Software Reliability Analysis to Example Software

    International Nuclear Information System (INIS)

    Kim, Man Cheol; Smidts, Carol

    2008-07-01

    The software reliability of TELLERFAST ATM software is analyzed by using two metric-based software reliability analysis methods, a state transition diagram-based method and a test coverage-based method. The procedures for the software reliability analysis by using the two methods and the analysis results are provided in this report. It is found that the two methods have a relation of complementary cooperation, and therefore further researches on combining the two methods to reflect the benefit of the complementary cooperative effect to the software reliability analysis are recommended

  1. How does a Collaborative Community Affect Diverse Students' Engagement with an Open Source Software Project: A Pedagogical Paradigm

    Science.gov (United States)

    Morgan, Becka S.

    Open Source Software (OSS) communities are homogenous and their lack of diversity is of concern to many within this field. This problem is becoming more pronounced as it is the practice of many technology companies to use OSS participation as a factor in the hiring process, disadvantaging those who are not a part of this community. We should expect that any field would have a population that reflects the general population given no constraints. The constraints within OSS are documented as being a hostile environment for women and minorities to participate in. Additionally OSS communities rely predominately on volunteers to create and maintain source code, documentation, and user interface as well as the organizational structure of the project. The volunteer nature of OSS projects creates a need for an ongoing pool of participants. This research addresses the lack of diversity along with the continual need for new members by developing a pedagogical paradigm that uses a collaborative environment to promote participation in an OSS project by diverse students. This collaborative environment used a Communities of Practice (CoP) framework to design the course, the indicators of which were used to operationalize the collaboration. The outcomes of this course not only benefit the students by providing them with skills necessary to continue participation and experience for getting a job, but also provide a diverse pool of volunteers for the OSS community. This diverse pool shows promise of creating a more diverse culture within OSS. In the development of this pedagogical paradigm this research looked primarily at student's perception of the importance of their group members and mentors provided to guide their participation in and contribution to an OSS community. These elements were used to facilitate the formation of a CoP. Self-efficacy was also used as a measure; an increase in self-efficacy is associated with the successful formation of a CoP. Finally the intent to

  2. Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects.

    Science.gov (United States)

    Shi, Zhenyu; Vickers, Claudia E

    2016-12-01

    Molecular Cloning Designer Simulator (MCDS) is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects. In addition to standard functions, it has a number of features that are either unique, or are not found in combination in any one software package: (1) it has a novel interactive flow-chart user interface for complex multi-step processes, allowing an integrated overview of the whole project; (2) it can perform a user-defined workflow of cloning steps in a single execution of the software; (3) it can handle multiple types of genetic recombineering, a technique that is rapidly replacing classical cloning for many applications; (4) it includes experimental information to conveniently guide wet lab work; and (5) it can store results and comments to allow the tracking and management of the whole project in one platform. MCDS is freely available from https://mcds.codeplex.com.

  3. ATM and checkpoint responses to DNA double strand breaks

    International Nuclear Information System (INIS)

    Khanna, K.K.

    2003-01-01

    DNA damage checkpoints can be classified into G1/S, intra-S and G2/M checkpoints, so named according to the cell cycle transitions that they regulate. DNA damage incurred during the G1 or G2 phase of the cell cycle leads to growth arrest at the G1/S and G2/M phase boundaries, respectively, whereas genotoxic stress during S phase results in the transient suppression of DNA synthesis. In mammals, ATM (ataxia-telangiectasia mutated) is a protein kinase that controls all checkpoint responses to DNA damage. ATM is a versatile kinase which uses various means to regulate a given checkpoint pathway. It has been shown to act upon several proteins within the same pathway, many times controlling several different modifications of the same protein or using several different targets to arrive at the same end point. Some of the ATM targets act as adaptors by recruiting additional substrates for ATM. ATM controls two types of responses in G1. The p53-dependent responses inhibit Cyclin/Cdk activity by transcriptional induction of p21, whereas p53-independent responses inhibit CDKs through degradation of Cdc25A to maintain CdK2 inhibitory phosphorylation. In regulating p53, ATM directly phosphorylates p53 on Ser15, which likely causes p53 transcriptional activation, concurrently activating other kinases that phosphorylate p53 at other sites such as Ser20, which reduces the ability of MDM2 to bind p53, thus promoting its stability. ATM further ensures p53 stability by phosphorylating MDM2. At least six ATM targets, namely CHK2, CHK1, NBS1, BRCA1, SMC1 and FANCD2, have been implicated in the control of S-phase checkpoint. Cdc25A is the downstream effector of CHK1 and CHK2, though the underlying mechanism for control of intra S-phase checkpoint by other targets remain obscure. G2 checkpoint prevents mitotic entry solely through inhibitory phosphorylation of Cdc2/Cdk1. Several ATM targets including CHK1, CHK2, BRCA1, MDC1 and p53BP1 have been implicated in the control of G2/M

  4. Structures of closed and open conformations of dimeric human ATM

    Science.gov (United States)

    Baretić, Domagoj; Pollard, Hannah K.; Fisher, David I.; Johnson, Christopher M.; Santhanam, Balaji; Truman, Caroline M.; Kouba, Tomas; Fersht, Alan R.; Phillips, Christopher; Williams, Roger L.

    2017-01-01

    ATM (ataxia-telangiectasia mutated) is a phosphatidylinositol 3-kinase–related protein kinase (PIKK) best known for its role in DNA damage response. ATM also functions in oxidative stress response, insulin signaling, and neurogenesis. Our electron cryomicroscopy (cryo-EM) suggests that human ATM is in a dynamic equilibrium between closed and open dimers. In the closed state, the PIKK regulatory domain blocks the peptide substrate–binding site, suggesting that this conformation may represent an inactive or basally active enzyme. The active site is held in this closed conformation by interaction with a long helical hairpin in the TRD3 (tetratricopeptide repeats domain 3) domain of the symmetry-related molecule. The open dimer has two protomers with only a limited contact interface, and it lacks the intermolecular interactions that block the peptide-binding site in the closed dimer. This suggests that the open conformation may be more active. The ATM structure shows the detailed topology of the regulator-interacting N-terminal helical solenoid. The ATM conformational dynamics shown by the structures represent an important step in understanding the enzyme regulation. PMID:28508083

  5. Software Architecture Evolution

    Science.gov (United States)

    Barnes, Jeffrey M.

    2013-01-01

    Many software systems eventually undergo changes to their basic architectural structure. Such changes may be prompted by new feature requests, new quality attribute requirements, changing technology, or other reasons. Whatever the causes, architecture evolution is commonplace in real-world software projects. Today's software architects, however,…

  6. The Impact of Project Role on Perceptions of Risk and Performance in Information Technology Software Development: A Comparative Analysis

    Science.gov (United States)

    Okongo, James

    2014-01-01

    The failure rate of information technology (IT) development projects is a significant concern for today's organizations. Perceptions of IT project risk and project performance have been identified as important factors by scholars studying the topic, and Wallace, Keil, and Rai (2004a) developed a survey instrument to measure how dimensions of…

  7. Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project.

    Science.gov (United States)

    Hucka, M; Finney, A; Bornstein, B J; Keating, S M; Shapiro, B E; Matthews, J; Kovitz, B L; Schilstra, M J; Funahashi, A; Doyle, J C; Kitano, H

    2004-06-01

    Biologists are increasingly recognising that computational modelling is crucial for making sense of the vast quantities of complex experimental data that are now being collected. The systems biology field needs agreed-upon information standards if models are to be shared, evaluated and developed cooperatively. Over the last four years, our team has been developing the Systems Biology Markup Language (SBML) in collaboration with an international community of modellers and software developers. SBML has become a de facto standard format for representing formal, quantitative and qualitative models at the level of biochemical reactions and regulatory networks. In this article, we summarise the current and upcoming versions of SBML and our efforts at developing software infrastructure for supporting and broadening its use. We also provide a brief overview of the many SBML-compatible software tools available today.

  8. Homeostatic regulation of meiotic DSB formation by ATM/ATR

    International Nuclear Information System (INIS)

    Cooper, Tim J.; Wardell, Kayleigh; Garcia, Valerie; Neale, Matthew J.

    2014-01-01

    Ataxia–telangiectasia mutated (ATM) and RAD3-related (ATR) are widely known as being central players in the mitotic DNA damage response (DDR), mounting responses to DNA double-strand breaks (DSBs) and single-stranded DNA (ssDNA) respectively. The DDR signalling cascade couples cell cycle control to damage-sensing and repair processes in order to prevent untimely cell cycle progression while damage still persists [1]. Both ATM/ATR are, however, also emerging as essential factors in the process of meiosis; a specialised cell cycle programme responsible for the formation of haploid gametes via two sequential nuclear divisions. Central to achieving accurate meiotic chromosome segregation is the introduction of numerous DSBs spread across the genome by the evolutionarily conserved enzyme, Spo11. This review seeks to explore and address how cells utilise ATM/ATR pathways to regulate Spo11-DSB formation, establish DSB homeostasis and ensure meiosis is completed unperturbed

  9. Homeostatic regulation of meiotic DSB formation by ATM/ATR

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, Tim J.; Wardell, Kayleigh; Garcia, Valerie; Neale, Matthew J., E-mail: m.neale@sussex.ac.uk

    2014-11-15

    Ataxia–telangiectasia mutated (ATM) and RAD3-related (ATR) are widely known as being central players in the mitotic DNA damage response (DDR), mounting responses to DNA double-strand breaks (DSBs) and single-stranded DNA (ssDNA) respectively. The DDR signalling cascade couples cell cycle control to damage-sensing and repair processes in order to prevent untimely cell cycle progression while damage still persists [1]. Both ATM/ATR are, however, also emerging as essential factors in the process of meiosis; a specialised cell cycle programme responsible for the formation of haploid gametes via two sequential nuclear divisions. Central to achieving accurate meiotic chromosome segregation is the introduction of numerous DSBs spread across the genome by the evolutionarily conserved enzyme, Spo11. This review seeks to explore and address how cells utilise ATM/ATR pathways to regulate Spo11-DSB formation, establish DSB homeostasis and ensure meiosis is completed unperturbed.

  10. Pragmatic Software Innovation

    DEFF Research Database (Denmark)

    Aaen, Ivan; Jensen, Rikke Hagensby

    2014-01-01

    We understand software innovation as concerned with introducing innovation into the development of software intensive systems, i.e. systems in which software development and/or integration are dominant considerations. Innovation is key in almost any strategy for competitiveness in existing markets......, for creating new markets, or for curbing rising public expenses, and software intensive systems are core elements in most such strategies. Software innovation therefore is vital for about every sector of the economy. Changes in software technologies over the last decades have opened up for experimentation......, learning, and flexibility in ongoing software projects, but how can this change be used to facilitate software innovation? How can a team systematically identify and pursue opportunities to create added value in ongoing projects? In this paper, we describe Deweyan pragmatism as the philosophical foundation...

  11. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.

    Directory of Open Access Journals (Sweden)

    Jan Karlseder

    2004-08-01

    Full Text Available The telomeric protein TRF2 is required to prevent mammalian telomeres from activating DNA damage checkpoints. Here we show that overexpression of TRF2 affects the response of the ATM kinase to DNA damage. Overexpression of TRF2 abrogated the cell cycle arrest after ionizing radiation and diminished several other readouts of the DNA damage response, including phosphorylation of Nbs1, induction of p53, and upregulation of p53 targets. TRF2 inhibited autophosphorylation of ATM on S1981, an early step in the activation of this kinase. A region of ATM containing S1981 was found to directly interact with TRF2 in vitro, and ATM immunoprecipitates contained TRF2. We propose that TRF2 has the ability to inhibit ATM activation at telomeres. Because TRF2 is abundant at chromosome ends but not elsewhere in the nucleus, this mechanism of checkpoint control could specifically block a DNA damage response at telomeres without affecting the surveillance of chromosome internal damage.

  12. AES Cardless Automatic Teller Machine (ATM) Biometric Security System Design Using FPGA Implementation

    Science.gov (United States)

    Ahmad, Nabihah; Rifen, A. Aminurdin M.; Helmy Abd Wahab, Mohd

    2016-11-01

    Automated Teller Machine (ATM) is an electronic banking outlet that allows bank customers to complete a banking transactions without the aid of any bank official or teller. Several problems are associated with the use of ATM card such card cloning, card damaging, card expiring, cast skimming, cost of issuance and maintenance and accessing customer account by third parties. The aim of this project is to give a freedom to the user by changing the card to biometric security system to access the bank account using Advanced Encryption Standard (AES) algorithm. The project is implemented using Field Programmable Gate Array (FPGA) DE2-115 board with Cyclone IV device, fingerprint scanner, and Multi-Touch Liquid Crystal Display (LCD) Second Edition (MTL2) using Very High Speed Integrated Circuit Hardware (VHSIC) Description Language (VHDL). This project used 128-bits AES for recommend the device with the throughput around 19.016Gbps and utilized around 520 slices. This design offers a secure banking transaction with a low rea and high performance and very suited for restricted space environments for small amounts of RAM or ROM where either encryption or decryption is performed.

  13. First research coordination meeting of the coordinated research project on validation of tracers and software for interwell investigations. Meeting report

    International Nuclear Information System (INIS)

    2004-01-01

    . The introduction and promotion of tracer techniques for oil producing industry have been going on through several national and regional technical cooperation projects. Presently, R and D is going on in interwell tracer technology, including development of new tracers, improvement of analytical and interpretation techniques, and other innovative techniques for multiphase flow pattern characterization. The CRP coordinates knowledge generated in this field to guarantee the continuity of technology and to transfer the best part to developing countries. For effective transfer of the technology to developing countries, the target techniques will be consolidated, developed further and validated though the CRP activities. Technical documents will also be prepared to facilitate upgradation of the capability of tracer groups in developing countries. In line with the CRP objectives, the first RCM summarized the status of tracer technology as applied to interwell tests and discussed the ways to meet the proposed goals. The proposed investigations were focused on three main fields: 1) Software and model development and interpretation, 2) development of new tracers, methods and technologies, and 3) field applications. All participants were encouraged to participate in one or more of these topics of discussion and establish networking activities

  14. How Does a Collaborative Community Affect Diverse Students' Engagement with an Open Source Software Project: A Pedagogical Paradigm

    Science.gov (United States)

    Morgan, Becka S.

    2012-01-01

    Open Source Software (OSS) communities are homogenous and their lack of diversity is of concern to many within this field. This problem is becoming more pronounced as it is the practice of many technology companies to use OSS participation as a factor in the hiring process, disadvantaging those who are not a part of this community. We should…

  15. SigmaPlot 2000, Version 6.00, SPSS Inc. Computer Software Project Management, Requirements, and Design Document

    Energy Technology Data Exchange (ETDEWEB)

    HURLBUT, S.T.

    2000-10-24

    SigmaPlot is a vendor software product that will be used to convert the area under an absorbance curve generated by a Fourier transform infrared spectrometer (FTIR) to a relative area. SigmaPlot will be used in conjunction with procedure ZA-565-301, ''Determination of Moisture by Supercritical Fluid Extraction and Infrared Detection.''

  16. Effects of Using Requirements Catalogs on Effectiveness and Productivity of Requirements Specification in a Software Project Management Course

    Science.gov (United States)

    Fernández-Alemán, José Luis; Carrillo-de-Gea, Juan Manuel; Meca, Joaquín Vidal; Ros, Joaquín Nicolás; Toval, Ambrosio; Idri, Ali

    2016-01-01

    This paper presents the results of two educational experiments carried out to determine whether the process of specifying requirements (catalog-based reuse as opposed to conventional specification) has an impact on effectiveness and productivity in co-located and distributed software development environments. The participants in the experiments…

  17. Open Source Software Development

    Science.gov (United States)

    2011-01-01

    appropriate to refer to FOSS or FLOSS (L for Libre , where the alternative term “ libre software ” has popularity in some parts of the world) in order...Applying Social Network Analysis to Community-Drive Libre Software Projects, Intern. J. Info. Tech. and Web Engineering, 2006, 1(3), 27-28. 17...Open Source Software Development* Walt Scacchi Institute for Software Researcher University of California, Irvine Irvine, CA 92697-3455 USA Abstract

  18. ATM signaling and genomic stability in response to DNA damage

    International Nuclear Information System (INIS)

    Lavin, Martin F.; Birrell, Geoff; Chen, Philip; Kozlov, Sergei; Scott, Shaun; Gueven, Nuri

    2005-01-01

    DNA double strand breaks represent the most threatening lesion to the integrity of the genome in cells exposed to ionizing radiation and radiomimetic chemicals. Those breaks are recognized, signaled to cell cycle checkpoints and repaired by protein complexes. The product of the gene (ATM) mutated in the human genetic disorder ataxia-telangiectasia (A-T) plays a central role in the recognition and signaling of DNA damage. ATM is one of an ever growing number of proteins which when mutated compromise the stability of the genome and predispose to tumour development. Mechanisms for recognising double strand breaks in DNA, maintaining genome stability and minimizing risk of cancer are discussed

  19. Software Quality Assurance Metrics

    Science.gov (United States)

    McRae, Kalindra A.

    2004-01-01

    Software Quality Assurance (SQA) is a planned and systematic set of activities that ensures conformance of software life cycle processes and products conform to requirements, standards and procedures. In software development, software quality means meeting requirements and a degree of excellence and refinement of a project or product. Software Quality is a set of attributes of a software product by which its quality is described and evaluated. The set of attributes includes functionality, reliability, usability, efficiency, maintainability, and portability. Software Metrics help us understand the technical process that is used to develop a product. The process is measured to improve it and the product is measured to increase quality throughout the life cycle of software. Software Metrics are measurements of the quality of software. Software is measured to indicate the quality of the product, to assess the productivity of the people who produce the product, to assess the benefits derived from new software engineering methods and tools, to form a baseline for estimation, and to help justify requests for new tools or additional training. Any part of the software development can be measured. If Software Metrics are implemented in software development, it can save time, money, and allow the organization to identify the caused of defects which have the greatest effect on software development. The summer of 2004, I worked with Cynthia Calhoun and Frank Robinson in the Software Assurance/Risk Management department. My task was to research and collect, compile, and analyze SQA Metrics that have been used in other projects that are not currently being used by the SA team and report them to the Software Assurance team to see if any metrics can be implemented in their software assurance life cycle process.

  20. ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication

    Science.gov (United States)

    Iwahori, Satoko; Kohmon, Daisuke; Kobayashi, Junya; Tani, Yuhei; Yugawa, Takashi; Komatsu, Kenshi; Kiyono, Tohru; Sugimoto, Nozomi; Fujita, Masatoshi

    2014-01-01

    Ataxia-telangiectasia mutated (ATM) plays crucial roles in DNA damage responses, especially with regard to DNA double-strand breaks (DSBs). However, it appears that ATM can be activated not only by DSB, but also by some changes in chromatin architecture, suggesting potential ATM function in cell cycle control. Here, we found that ATM is involved in timely degradation of Cdt1, a critical replication licensing factor, during the unperturbed S phase. At least in certain cell types, degradation of p27Kip1 was also impaired by ATM inhibition. The novel ATM function for Cdt1 regulation was dependent on its kinase activity and NBS1. Indeed, we found that ATM is moderately phosphorylated at Ser1981 during the S phase. ATM silencing induced partial reduction in levels of Skp2, a component of SCFSkp2 ubiquitin ligase that controls Cdt1 degradation. Furthermore, Skp2 silencing resulted in Cdt1 stabilization like ATM inhibition. In addition, as reported previously, ATM silencing partially prevented Akt phosphorylation at Ser473, indicative of its activation, and Akt inhibition led to modest stabilization of Cdt1. Therefore, the ATM-Akt-SCFSkp2 pathway may partly contribute to the novel ATM function. Finally, ATM inhibition rendered cells hypersensitive to induction of re-replication, indicating importance for maintenance of genome stability. PMID:24280901

  1. Results of a Survey Software Development Project Management in the U.S. Aerospace Industry. Volume III. Major Problems.

    Science.gov (United States)

    1979-12-18

    simplifies the staffing of a project and assures the experience is ’ recyclable ’." "Staff or members are considered ’universal experts’. During estimation...impact of changes upon the original system." "Project reviews are typically exercises in trivia ." [Keider, 1974] ____ ,,, , _ 55 "First, [lesson

  2. Distributed medical services within the ATM-based Berlin regional test bed

    Science.gov (United States)

    Thiel, Andreas; Bernarding, Johannes; Krauss, Manfred; Schulz, Sandra; Tolxdorff, Thomas

    1996-05-01

    The ATM-based Metropolitan Area Network (MAN) of Berlin connects two university hospitals (Benjamin Franklin University Hospital and Charite) with the computer resources of the Technical University of Berlin (TUB). Distributed new medical services have been implemented and will be evaluated within the highspeed MAN of Berlin. The network with its data transmission rates of up to 155 Mbit/s renders these medical services externally available to practicing physicians. Resource and application sharing is demonstrated by the use of two software systems. The first software system is an interactive 3D reconstruction tool (3D- Medbild), based on a client-server mechanism. This structure allows the use of high- performance computers at the TUB from the low-level workstations in the hospitals. A second software system, RAMSES, utilizes a tissue database of Magnetic Resonance Images. For the remote control of the software, the developed applications use standards such as DICOM 3.0 and features of the World Wide Web. Data security concepts are being tested and integrated for the needs of the sensitive medical data. The highspeed network is the necessary prerequisite for the clinical evaluation of data in a joint teleconference. The transmission of digitized real-time sequences such as video and ultrasound and the interactive manipulation of data are made possible by Multi Media tools.

  3. The Evolution of a Science Project: A Preliminary System Dynamics Model of a Recurring Software-Reliant Acquisition Behavior

    Science.gov (United States)

    2012-07-01

    Complexity?” Proceedings of the Third Annual Conference on Software- Intensive Systems Acquisition, January 2004. [ Bandura 1986] Bandura , Albert ...Andrew P. Moore Christopher Alberts July 2012 TECHNICAL REPORT CMU/SEI-2012-TR-001 ESC-TR-2012-001 Acquisition Support Program http...an operational environment [ Bandura 1986]. Creating interactive experiential learning tools such as “flight simulators” for use in the classroom is

  4. Adaptive Restoration of Airborne Daedalus AADS1268 ATM Thermal Data

    International Nuclear Information System (INIS)

    D. Yuan; E. Doak; P. Guss; A. Will

    2002-01-01

    To incorporate the georegistration and restoration processes into airborne data processing in support of U.S. Department of Energy's nuclear emergency response task, we developed an adaptive restoration filter for airborne Daedalus AADS1268 ATM thermal data based on the Wiener filtering theory. Preliminary assessment shows that this filter enhances the detectability of small weak thermal anomalies in AADS1268 thermal images

  5. Characterization of spent fuel approved testing material: ATM-106

    International Nuclear Information System (INIS)

    Guenther, R.J.; Blahnik, D.E.; Campbell, T.K.; Jenquin, U.P.; Mendel, J.E.; Thornhill, C.K.

    1988-10-01

    The characterization data obtained to date are described for Approved Testing Material (ATM)-106 spent fuel from Assembly BT03 of pressurized-water reactor Calvert Cliffs No. 1. This report is one in a series being prepared by the Materials Characterization Center at Pacific Northwest Laboratory on spent fuel ATMs. The ATMs are receiving extensive examinations to provide a source of well- characterized spent fuel for testing in the US Department of Energy Office of Civilian Radioactive Waste Management (OCWRM) program. ATM-106 consists of 20 full-length irradiated fuel rods with rod-average burnups of about 3700 GJ/kgM (43 MWd/kgM) and expected fission gas release of /approximately/10%. Characterization data include (1) as-fabricated fuel design, irradiation history, and subsequent storage and handling; (2) isotopic gamma scans; (3) fission gas analyses; (4) ceramography of the fuel and metallography of the cladding; (5) calculated nuclide inventories and radioactivities in the fuel and cladding; and (6) radiochemical analyses of the fuel and cladding. Additional analyses of the fuel rod are being conducted and will be included in planned revisions of this report. 12 refs., 110 figs., 81 tabs

  6. The ATM gene and the radiobiology of ataxia-telangiectasia

    International Nuclear Information System (INIS)

    Jorgensen, T.J.; Shiloh, Y.

    1996-01-01

    Ataxia-telangiectasia (A-T) is the classic human genetic disease involving severe ionizing radiation sensitivity and as such has been intensely studied by radiation biologists over the years. Unlike its counterpart for UV light sensitivity -xeroderma pigmentosum - A-T has no obvious DNA repair defect; and there has been much speculation as to the mechanism underlying the altered radioresponses associated with this disease. The gene defective in A-T (ATM) has recently been cloned, and its primary coding sequence determined. The primary sequence of the ATM protein suggests that it has some regulatory functions related to cellular radioresponse and maintenance of genomic stability, and shares these functions with a growing family of other proteins in various organisms. At this juncture it is appropriate to review our current knowledge about the radiobiology of A-T and reflect on the possible radiobiological mechanisms that are suggested by the ATM gene itself. This article will attempt briefly to review current knowledge about the radiobiology of A-T and to introduce new speculations about underlying radiobiological mechanisms that are suggested by the primary amino acid sequence of the predicted ATM gene product. (Author)

  7. The ATM signaling network in development and disease

    Science.gov (United States)

    Stracker, Travis H.; Roig, Ignasi; Knobel, Philip A.; Marjanović, Marko

    2013-01-01

    The DNA damage response (DDR) rapidly recognizes DNA lesions and initiates the appropriate cellular programs to maintain genome integrity. This includes the coordination of cell cycle checkpoints, transcription, translation, DNA repair, metabolism, and cell fate decisions, such as apoptosis or senescence (Jackson and Bartek, 2009). DNA double-strand breaks (DSBs) represent one of the most cytotoxic DNA lesions and defects in their metabolism underlie many human hereditary diseases characterized by genomic instability (Stracker and Petrini, 2011; McKinnon, 2012). Patients with hereditary defects in the DDR display defects in development, particularly affecting the central nervous system, the immune system and the germline, as well as aberrant metabolic regulation and cancer predisposition. Central to the DDR to DSBs is the ataxia-telangiectasia mutated (ATM) kinase, a master controller of signal transduction. Understanding how ATM signaling regulates various aspects of the DDR and its roles in vivo is critical for our understanding of human disease, its diagnosis and its treatment. This review will describe the general roles of ATM signaling and highlight some recent advances that have shed light on the diverse roles of ATM and related proteins in human disease. PMID:23532176

  8. Utilisation des modules ATM pour le projet FP420

    CERN Document Server

    Renaglia, T

    2006-01-01

    Le but de cette note est de résumer les premières caractéristiques de l'intégration de 2 modules ATM pour le projet FP420 (voir note technique EDMS n° 743628) ainsi que la liste des problèmes découverts à ce jour sur l

  9. Germline variants in the ATM gene and breast cancer susceptibility ...

    African Journals Online (AJOL)

    Chaymaa Marouf

    2017-03-06

    Mar 6, 2017 ... Results: We did not detect the ATM c.7271T > G and c.1066–6T > G (IVS10–6T > G) ..... [8] Lavin MF, Shiloh Y. The genetic defect in ataxia-telangiectasia. .... [36] Inskip HM, Kinlen LJ, Taylor AM, Woods CG, Arlett CF. Risk of ...

  10. The ATM signaling network in development and disease

    Directory of Open Access Journals (Sweden)

    Travis H. Stracker

    2013-03-01

    Full Text Available The DNA damage response (DDR rapidly recognizes DNA lesions and initiates the appropriate cellular programs to maintain genome integrity. This includes the coordination of cell cycle checkpoints, transcription, translation, DNA repair, metabolism and cell fate decisions, such as apoptosis or senescence(Jackson and Bartek, 2009. DNA double-strand breaks (DSBs represent one of the most cytotoxic DNA lesions and defects in their metabolism underlie many human hereditary diseases characterized by genomic instability(Stracker and Petrini, 2011;McKinnon, 2012. Patients with hereditary defects in the DDR display defects in development, particularly affecting the central nervous system (CNS, the immune system and the germline, as well as aberrant metabolic regulation and cancer predisposition. Central to the DDR to DSBs is the ATM kinase, a master controller of signal transduction. Understanding how ATM signaling regulates various aspects of the DDR and its roles in vivo is critical for our understanding of human disease, its diagnosis and its treatment. This review will describe the general roles of ATM signaling and highlight some recent advances that have shed light on the diverse roles of ATM and related proteins in human disease.

  11. Characterization of spent fuel approved testing material---ATM-105

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, R.J.; Blahnik, D.E.; Campbell, T.K.; Jenquin, U.P.; Mendel, J.E.; Thomas, L.E.; Thornhill, C.K.

    1991-12-01

    The characterization data obtained to data are described for Approved Testing Material 105 (ATM-105), which is spent fuel from Bundles CZ346 and CZ348 of the Cooper Nuclear Power Plant, a boiling-water reactor. This report is one in a series being prepared by the Materials Characterization Center at Pacific Northwest Laboratory (PNL) on spent fuel ATMs. The ATMs are receiving extensive examinations to provide a source of well-characterized spent fuel for testing in the US Department of Energy Office of Civilian Radioactive Waste Management (OCRWM) Program. ATM-105 consists of 88 full-length irradiated fuel rods with rod-average burnups of about 2400 GJ/kgM (28 MWd/kgM) and expected fission gas release of about 1%. Characterization data include (1) descriptions of as-fabricated fuel design, irradiation history, and subsequent storage and handling; (2) isotopic gamma scans; (3) fission gas analyses; (4) ceramography of the fuel and metallography of the cladding; (5) special fuel studies involving analytical transmission electron microscopy (AEM); (6) calculated nuclide inventories and radioactivities in the fuel and cladding; and (7) radiochemical analyses of the fuel and cladding. Additional analyses of the fuel are being conducted and will be included in planned revisions of this report.

  12. ATM down-regulation is associated with poor prognosis in sporadic breast carcinomas

    DEFF Research Database (Denmark)

    Bueno, R C; Canevari, R A; Villacis, R A R

    2014-01-01

    BACKGROUND: Ataxia telangiectasia-mutated (ATM) gene downexpression has been reported in sporadic breast carcinomas (BC); however, the prognostic value and mechanisms of ATM deregulation remain unclear. PATIENTS AND METHODS: ATM and miRNAs (miR-26a, miR-26b, miR-203, miR-421, miR-664, miR-576-5p...... and miR-18a) expression levels were evaluated by quantitative real-time PCR (RT-qPCR) in 52 BC and 3 normal breast samples. ATM protein expression was assessed by immunohistochemistry in 968 BC and 35 adjacent normal breast tissues. ATM copy number alteration was detected by array comparative genomic...... hybridization (aCGH) in 42 tumours. RESULTS: Low ATM levels were associated with tumour grade. Absence of ATM protein expression was associated with distant metastasis (P ATM...

  13. Business Management Software Axolon ERP

    OpenAIRE

    Axolon ERP Solution

    2018-01-01

    Axolon ERP a Business Management Software www.axolonerp.com by Micromind is a comprehensive business management software solution for businesses. We deliver Business Management Software Dubai in UAE, GCC Countries and products also include ERP Software Dubai. HR & Payroll, Inventory Software, Project Management, Software Development, Solutions and Services in Dubai, UAE for small and medium sized Enterprises (SME) in the middle east with a easy-to-use, secure and efficient business management...

  14. A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant.

    Science.gov (United States)

    Rimkus, Stacey A; Wassarman, David A

    2018-01-01

    Ataxia-telangiectasia (A-T) is a neurodegenerative disease caused by mutation of the A-T mutated (ATM) gene. ATM encodes a protein kinase that is activated by DNA damage and phosphorylates many proteins, including those involved in DNA repair, cell cycle control, and apoptosis. Characteristic biological and molecular functions of ATM observed in mammals are conserved in Drosophila melanogaster. As an example, conditional loss-of-function ATM alleles in flies cause progressive neurodegeneration through activation of the innate immune response. However, unlike in mammals, null alleles of ATM in flies cause lethality during development. With the goals of understanding biological and molecular roles of ATM in a whole animal and identifying candidate therapeutics for A-T, we performed a screen of 2400 compounds, including FDA-approved drugs, natural products, and bioactive compounds, for modifiers of the developmental lethality caused by a temperature-sensitive ATM allele (ATM8) that has reduced kinase activity at non-permissive temperatures. Ten compounds reproducibly suppressed the developmental lethality of ATM8 flies, including Ronnel, which is an organophosphate. Ronnel and other suppressor compounds are known to cause mitochondrial dysfunction or to inhibit the enzyme acetylcholinesterase, which controls the levels of the neurotransmitter acetylcholine, suggesting that detrimental consequences of reduced ATM kinase activity can be rescued by inhibiting the function of mitochondria or increasing acetylcholine levels. We carried out further studies of Ronnel because, unlike the other compounds that suppressed the developmental lethality of homozygous ATM8 flies, Ronnel was toxic to the development of heterozygous ATM8 flies. Ronnel did not affect the innate immune response of ATM8 flies, and it further increased the already high levels of DNA damage in brains of ATM8 flies, but its effects were not harmful to the lifespan of rescued ATM8 flies. These results provide

  15. A Demonstration of the System Assessment Capability (SAC) Rev. 1 Software for the Hanford Remediation Assessment Project

    International Nuclear Information System (INIS)

    Eslinger, Paul W.; Kincaid, Charles T.; Nichols, William E.; Wurstner, Signe K.

    2006-01-01

    The System Assessment Capability (SAC) is a suite of interrelated computer codes that provides the capability to conduct large-scale environmental assessments on the Hanford Site. Developed by Pacific Northwest National Laboratory for the Department of Energy, SAC models the fate and transport of radioactive and chemical contaminants, starting with the inventory of those contaminants in waste sites, simulating transport through the environment, and continuing on through impacts to the environment and humans. Separate modules in the SAC address inventory, release from waste forms, water flow and mass transport in the vadose zone, water flow and mass transport in the groundwater, water flow and mass transport in the Columbia River, air transport, and human and ecological impacts. The SAC supports deterministic analyses as well as stochastic analyses using a Monte Carlo approach, enabling SAC users to examine the effect of uncertainties in a number of key parameters. The initial assessment performed with the SAC software identified a number of areas where both the software and the analysis approach could be improved. Since that time the following six major software upgrades have been made: (1) An air pathway model was added to support all-pathway analyses. (2) Models for releases from glass waste forms, buried graphite reactor cores, and buried naval reactor compartments were added. (3) An air-water dual-phase model was added to more accurately track the movement of volatile contaminants in the vadose zone. (4) The ability to run analyses was extended from 1,000 years to 10,000 years or longer after site closure. (5) The vadose zone flow and transport model was upgraded to support two-dimensional or three-dimensional analyses. (6) The ecological model and human risk models were upgraded so the concentrations of contaminants in food products consumed by humans are produced by the ecological model. This report documents the functions in the SAC software and provides a

  16. A Demonstration of the System Assessment Capability (SAC) Rev. 1 Software for the Hanford Remediation Assessment Project

    Energy Technology Data Exchange (ETDEWEB)

    Eslinger, Paul W.; Kincaid, Charles T.; Nichols, William E.; Wurstner, Signe K.

    2006-11-06

    The System Assessment Capability (SAC) is a suite of interrelated computer codes that provides the capability to conduct large-scale environmental assessments on the Hanford Site. Developed by Pacific Northwest National Laboratory for the Department of Energy, SAC models the fate and transport of radioactive and chemical contaminants, starting with the inventory of those contaminants in waste sites, simulating transport through the environment, and continuing on through impacts to the environment and humans. Separate modules in the SAC address inventory, release from waste forms, water flow and mass transport in the vadose zone, water flow and mass transport in the groundwater, water flow and mass transport in the Columbia River, air transport, and human and ecological impacts. The SAC supports deterministic analyses as well as stochastic analyses using a Monte Carlo approach, enabling SAC users to examine the effect of uncertainties in a number of key parameters. The initial assessment performed with the SAC software identified a number of areas where both the software and the analysis approach could be improved. Since that time the following six major software upgrades have been made: (1) An air pathway model was added to support all-pathway analyses. (2) Models for releases from glass waste forms, buried graphite reactor cores, and buried naval reactor compartments were added. (3) An air-water dual-phase model was added to more accurately track the movement of volatile contaminants in the vadose zone. (4) The ability to run analyses was extended from 1,000 years to 10,000 years or longer after site closure. (5) The vadose zone flow and transport model was upgraded to support two-dimensional or three-dimensional analyses. (6) The ecological model and human risk models were upgraded so the concentrations of contaminants in food products consumed by humans are produced by the ecological model. This report documents the functions in the SAC software and provides a

  17. ATM Technology and Banking System in West African Sub-Region ...

    African Journals Online (AJOL)

    User

    2011-04-19

    Apr 19, 2011 ... At this point in time, it is pertinent to ask, what is ATM? ATM is Automated .... can be installed on ATMs running Microsoft Windows XP operating system that records sensitive ... almost real time bank services. The citizens of ...

  18. Knowledge-Based Multiple Access Protocol in Broadband Wireless ATM Networks

    DEFF Research Database (Denmark)

    Liu, Hong; Gliese, Ulrik Bo; Dittmann, Lars

    1999-01-01

    In this paper, we propose a knowledge-based multiple access protocol for the extension of wireline ATM to wireless networks. The objective is to enable effecient transmission of all kinds of ATM traffic in the wireless channel with guaranteed QoS.The proposed protocol utilixes knowledge of the main...... guaranteed QoS requirements to a variety of ATM applications....

  19. A 2.5 gb/s GaAs ATM Mux Demux ASIC

    DEFF Research Database (Denmark)

    Madsen, Jens Kargaard; Lassen, Peter Stuhr

    1995-01-01

    This paper describes the design and implementation of a high speed GaAs ATM Mux Demur ASIC (AMDA) which is the key element in a high speed ATM Add-Drop unit. This unit is used in a new distributed ATM multiplexing-demultiplexing architecture for broadband switching systems. The Add-Drop unit...

  20. ATM Technology and Banking System in West African Sub-Region ...

    African Journals Online (AJOL)

    Automated Teller Machine (ATM) technology has had its significant impact in banking system in Nigeria and some other West African Countries. The most significant impact of ATM technology is the customer's ability to withdraw money outside banking hours. But this feat achieved by ATM technology is not without ...

  1. Software Engineering Improvement Plan

    Science.gov (United States)

    2006-01-01

    In performance of this task order, bd Systems personnel provided support to the Flight Software Branch and the Software Working Group through multiple tasks related to software engineering improvement and to activities of the independent Technical Authority (iTA) Discipline Technical Warrant Holder (DTWH) for software engineering. To ensure that the products, comments, and recommendations complied with customer requirements and the statement of work, bd Systems personnel maintained close coordination with the customer. These personnel performed work in areas such as update of agency requirements and directives database, software effort estimation, software problem reports, a web-based process asset library, miscellaneous documentation review, software system requirements, issue tracking software survey, systems engineering NPR, and project-related reviews. This report contains a summary of the work performed and the accomplishments in each of these areas.

  2. The whiteStar development project: Westinghouse's next generation core design simulator and core monitoring software to power the nuclear renaissance

    International Nuclear Information System (INIS)

    Boyd, W. A.; Mayhue, L. T.; Penkrot, V. S.; Zhang, B.

    2009-01-01

    The WhiteStar project has undertaken the development of the next generation core analysis and monitoring system for Westinghouse Electric Company. This on-going project focuses on the development of the ANC core simulator, BEACON core monitoring system and NEXUS nuclear data generation system. This system contains many functional upgrades to the ANC core simulator and BEACON core monitoring products as well as the release of the NEXUS family of codes. The NEXUS family of codes is an automated once-through cross section generation system designed for use in both PWR and BWR applications. ANC is a multi-dimensional nodal code for all nuclear core design calculations at a given condition. ANC predicts core reactivity, assembly power, rod power, detector thimble flux, and other relevant core characteristics. BEACON is an advanced core monitoring and support system which uses existing instrumentation data in conjunction with an analytical methodology for on-line generation and evaluation of 3D core power distributions. This new system is needed to design and monitor the Westinghouse AP1000 PWR. This paper describes provides an overview of the software system, software development methodologies used as well some initial results. (authors)

  3. Multi-dimensional project evaluation: Combining cost-benefit analysis and multi-criteria analysis with the COSIMA software system

    DEFF Research Database (Denmark)

    and not the least construction and maintenance costs. The MCA is made use of to assess noise, land use planning, business potential and tourism impacts for the three alternatives. More technically the software system offers a set of different features to undertake the MCA. Thus the users have two different methods...... for society is ranked uppermost. To compare the different impacts, it is necessary to have a common monetary unit. Theoretically, all benefits and all costs should be accounted for in socio-economic cost-benefit analysis. However, this is far from in practical the general case due to difficulties...... in a valuating all the criteria in monetary terms. Thus CBA does not meet the need for a comprehensive evaluation, for which reason MCA is introduced to overcome this problem. Not only does MCA provides an opportunity to include non-market impacts in the analysis, but MCA also provides a framework for breaking...

  4. Software engineering in industry

    Science.gov (United States)

    Story, C. M.

    1989-12-01

    Can software be "engineered"? Can a few people with limited resources and a negligible budget produce high quality software solutions to complex software problems? It is possible to resolve the conflict between research activities and the necessity to view software development as a means to an end rather than as an end in itself? The aim of this paper is to encourage further thought and discussion on various topics which, in the author's experience, are becoming increasingly critical in large current software production and development projects, inside and outside high energy physics (HEP). This is done by briefly exploring some of the software engineering ideas and technologies now used in the information industry, using, as a case-study, a project with many similarities to those currently under way in HEP.

  5. Fabrication and characterization of MCC approved testing material - ATM-8 glass

    International Nuclear Information System (INIS)

    Wald, J.W.

    1985-10-01

    The Materials Characterization Center (MCC) Approved Testing Material ATM-8 is a borosilicate glass that incorporates elements typical of high-level waste (HLW) resulting from the reprocessing of commercial nuclear reactor fuel. Its composition is based upon the simulated HLW glass type 76-68 (Mendel, J.E. et al., 1977, Annual Report of the Characteristics of High-Level Waste Glasses, BNWL-2252, Pacific Northwest Laboratory, Richland, Washington), to which depleted uranium, technetium-99, neptunium-237 and plutonium-239 have been added at moderate to low levels. The glass was requested by the Nevada Nuclear Waste Storage Investigations (NNWSI) Project. It was produced by the MCC at the Pacific Northwest Laboratory (PNL) operated for the Department of Energy (DOE) by Battelle Memorial Institute. ATM-8 glass was produced in April of 1984, and is the second in a series of testing materials for NNWSI. This report discusses its fabrication (starting materials, batch and glass preparation, measurement and testing equipment, other equipment, procedures, identification system and materials availability and storage, and characterization (bulk density) measurements, chemical analysis, microscopic examination, and x-ray diffraction analysis. 4 refs., 2 figs., 10 tabs

  6. Comparative study on software development methodologies

    OpenAIRE

    Mihai Liviu DESPA

    2014-01-01

    This paper focuses on the current state of knowledge in the field of software development methodologies. It aims to set the stage for the formalization of a software development methodology dedicated to innovation orientated IT projects. The paper starts by depicting specific characteristics in software development project management. Managing software development projects involves techniques and skills that are proprietary to the IT industry. Also the software development project manager han...

  7. ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib.

    Science.gov (United States)

    Wang, Chen; Jette, Nicholas; Moussienko, Daniel; Bebb, D Gwyn; Lees-Miller, Susan P

    2017-04-01

    The ataxia telangiectasia mutated (ATM) protein kinase plays a central role in the cellular response to DNA damage. Loss or inactivation of both copies of the ATM gene (ATM) leads to ataxia telangiectasia, a devastating childhood condition characterized by neurodegeneration, immune deficiencies, and cancer predisposition. ATM is also absent in approximately 40% of mantle cell lymphomas (MCLs), and we previously showed that MCL cell lines with loss of ATM are sensitive to poly-ADP ribose polymerase (PARP) inhibitors. Next-generation sequencing of patient tumors has revealed that ATM is altered in many human cancers including colorectal, lung, prostate, and breast. Here, we show that the colorectal cancer cell line SK-CO-1 lacks detectable ATM protein expression and is sensitive to the PARP inhibitor olaparib. Similarly, HCT116 colorectal cancer cells with shRNA depletion of ATM are sensitive to olaparib, and depletion of p53 enhances this sensitivity. Moreover, HCT116 cells are sensitive to olaparib in combination with the ATM inhibitor KU55933, and sensitivity is enhanced by deletion of p53. Together our studies suggest that PARP inhibitors may have potential for treating colorectal cancer with ATM dysfunction and/or colorectal cancer with mutation of p53 when combined with an ATM kinase inhibitor. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Absence of Wip1 partially rescues Atm deficiency phenotypes in mice

    Science.gov (United States)

    Darlington, Yolanda; Nguyen, Thuy-Ai; Moon, Sung-Hwan; Herron, Alan; Rao, Pulivarthi; Zhu, Chengming; Lu, Xiongbin; Donehower, Lawrence A.

    2011-01-01

    Wildtype p53-Induced Phosphatase 1 (WIP1) is a serine/threonine phosphatase that dephosphorylates proteins in the ataxia telangiectasia mutated (ATM)-initiated DNA damage response pathway. WIP1 may play a homeostatic role in ATM signaling by returning the cell to a normal pre-stress state following completion of DNA repair. To better understand the effects of WIP1 on ATM signaling, we crossed Atm-deficient mice to Wip1-deficient mice and characterized phenotypes of the double knockout progeny. We hypothesized that the absence of Wip1 might rescue Atm deficiency phenotypes. Atm null mice, like ATM-deficient humans with the inherited syndrome ataxia telangiectasia, exhibit radiation sensitivity, fertility defects, and are T-cell lymphoma prone. Most double knockout mice were largely protected from lymphoma development and had a greatly extended lifespan compared to Atm null mice. Double knockout mice had increased p53 and H2AX phosphorylation and p21 expression compared to their Atm null counterparts, indicating enhanced p53 and DNA damage responses. Additionally, double knockout splenocytes displayed reduced chromosomal instability compared to Atm null mice. Finally, doubly null mice were partially rescued from infertility defects observed in Atm null mice. These results indicate that inhibition of WIP1 may represent a useful strategy for cancer treatment in general and A-T patients in particular. PMID:21765465

  9. Digital Coin Business Model Using the Coin ATM

    Science.gov (United States)

    Jung, Won-Gyo; Park, Sang-Sung; Shin, Young-Geun; Jang, Dong-Sik

    2009-08-01

    Because about 83.6 billion won worth coins are not collected annually, 35 billion won of government money is being wasted for producing new coins in Korea. In order to improve unnecessary government money leakage, we now have to develop a proper way of managing small valued money such as coins. We have already developed the coin ATM to solve such problem in the previous study. In this study, we proposed business model, which enables users to deposit or consume such small amount of money with the coin ATM. The proposed business model has advantages that enable to connect various payment system and is efficient to consume such small amount of money. This business model improves not only the way of managing small valued money but also the way of consuming small valued money. Furthermore, our business model can contribute to activating circulation of coins as well as preventing leakage of government money.

  10. Participation of ATM in cellular response to DNA damage induced by ionizing radiation

    International Nuclear Information System (INIS)

    Meng Xiangbing; Song Yi; Mao Jianping; Gong Bo; Dong Yan; Liu Bin; Sun Zhixian

    2000-01-01

    Objective: To clone ATM full length cDNA and cDNA fragments containing some functional domains and to identify proteins that interact with ATM and mediate DNA damage signal transduction in cellular response to DNA damage. Methods: ATM cDNA was amplified from MarthomTM-Ready cDNA kit of human leukocytes by LD-PCR. ATM-interacting proteins were screened by yeast two hybrid system. Results: ATM full-length cDNA and cDNA fragments containing PI3K kinase domain, leucine zipper and proline rich region were amplified from human cDNAs. Several candidate clones that interacted with ATM PI3K domain were identified. Conclusion: ATM mediates DNA damage signal transduction by interacting with many proteins

  11. Phosphorylation of p300 by ATM controls the stability of NBS1

    International Nuclear Information System (INIS)

    Jang, Eun Ryoung; Choi, Jae Duk; Jeong, Gajin; Lee, Jong-Soo

    2010-01-01

    Acetyltransferase, p300 is a transcriptional cofactor of signal-responsive transcriptional regulation. The surveillance kinase ataxia-telangiectasia mutated (ATM) plays a central role in regulation of a wide range of cellular DNA damage responses. Here, we investigated whether and how ATM mediates phosphorylation of p300 in response to DNA damage and how p300 phosphorylation is functionally linked to DNA damage. ATM-phosphorylated p300 in vitro and in vivo, in response to DNA damage. Phosphorylation of p300 proteins was observed upon γ-irradiation in ATM + cells but not ATM - cells. Importantly, expression of nonphosphorylatable serine to alanine form of p300 (S106A) destabilized both p300 and NBS1 proteins, after DNA damage. These data demonstrate that ATM transduces a DNA damage signal to p300, and that ATM-dependent phosphorylation of p300 is required for stabilization of NBS1 proteins in response to DNA damage.

  12. Hospital Management Software Development

    OpenAIRE

    sobogunGod, olawale

    2012-01-01

    The purpose of this thesis was to implement a hospital management software which is suitable for small private hospitals in Nigeria, especially for the ones that use a file based system for storing information rather than having it stored in a more efficient and safer environment like databases or excel programming software. The software developed within this thesis project was specifically designed for the Rainbow specialist hospital which is based in Lagos, the commercial neurological cente...

  13. FASTBUS software status

    International Nuclear Information System (INIS)

    Gustavson, D.B.

    1980-10-01

    Computer software will be needed in addition to the mechanical, electrical, protocol and timing specifications of the FASTBUS, in order to facilitate the use of this flexible new multiprocessor and multisegment data acquisition and processing system. Software considerations have been important in the FASTBUS design, but standard subroutines and recommended algorithms will be needed as the FASTBUS comes into use. This paper summarizes current FASTBUS software projects, goals and status

  14. Solar Asset Management Software

    Energy Technology Data Exchange (ETDEWEB)

    Iverson, Aaron [Ra Power Management, Inc., Oakland, CA (United States); Zviagin, George [Ra Power Management, Inc., Oakland, CA (United States)

    2016-09-30

    Ra Power Management (RPM) has developed a cloud based software platform that manages the financial and operational functions of third party financed solar projects throughout their lifecycle. RPM’s software streamlines and automates the sales, financing, and management of a portfolio of solar assets. The software helps solar developers automate the most difficult aspects of asset management, leading to increased transparency, efficiency, and reduction in human error. More importantly, our platform will help developers save money by improving their operating margins.

  15. CaC in ATM – the Diffuse Method

    OpenAIRE

    I. Baroňák; M. Vozňák

    2006-01-01

    Connection Admission Control is an element in the of preclusive mechanisms of ATM management. Its main task is to prevent overloading of the network and to ensure the required quality of service. This means that it has to predict the service of the network and according to its state it can manage both existing and new connections. This paper deals with the diffuse method, a CAC method that enables us to obtain the required results. 

  16. Analysis of expected ATM processes changes in Central Europe

    Directory of Open Access Journals (Sweden)

    Tomislav MIHETEC

    2012-01-01

    Full Text Available This paper evaluates feasibility of the new Air Traffic Management (ATM organisation in Functional Airspace Block Central Europe (FAB CE and specifies the implementation scenarios that are proposed by Central European Air Traffic Services Coordination Group (CEATS CG. The paper elaborates elements of required Functional Airspace Block Central Europe implementation and identifies and assesses the implementation blockers. Provision of air navigation services in European Civil Aviation Conference (ECAC area is diversely regulated and highly fragmented.

  17. Wireless ATM: A Technologi cal Framework to m-banking

    OpenAIRE

    Susmi Routray; A. M. Sherry; B. V. R. Reddy

    2008-01-01

    Mobile and Wireless communication devices are becoming enablers for organizations to conduct business more effectively and efficiently. One of the most effective applications is mobile banking (m-banking). For any application to gain recognition technological advancements play a vital role. To make m-banking application a success bandwidth management is an important issue. The incr eased flexibility and mobility feature of wireless ATM and its bandwidth on demand fu...

  18. NASA's Software Safety Standard

    Science.gov (United States)

    Ramsay, Christopher M.

    2007-01-01

    NASA relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations. Since the 1960's there has hardly been a spacecraft launched that does not have a computer on board that will provide command and control services. There have been recent incidents where software has played a role in high-profile mission failures and hazardous incidents. For example, the Mars Orbiter, Mars Polar Lander, the DART (Demonstration of Autonomous Rendezvous Technology), and MER (Mars Exploration Rover) Spirit anomalies were all caused or contributed to by software. The Mission Control Centers for the Shuttle, ISS, and unmanned programs are highly dependant on software for data displays, analysis, and mission planning. Despite this growing dependence on software control and monitoring, there has been little to no consistent application of software safety practices and methodology to NASA's projects with safety critical software. Meanwhile, academia and private industry have been stepping forward with procedures and standards for safety critical systems and software, for example Dr. Nancy Leveson's book Safeware: System Safety and Computers. The NASA Software Safety Standard, originally published in 1997, was widely ignored due to its complexity and poor organization. It also focused on concepts rather than definite procedural requirements organized around a software project lifecycle. Led by NASA Headquarters Office of Safety and Mission Assurance, the NASA Software Safety Standard has recently undergone a significant update. This new standard provides the procedures and guidelines for evaluating a project for safety criticality and then lays out the minimum project lifecycle requirements to assure the software is created, operated, and maintained in the safest possible manner. This update of the standard clearly delineates the minimum set of software safety requirements for a project without detailing the implementation for those

  19. ATM is required for SOD2 expression and homeostasis within the mammary gland.

    Science.gov (United States)

    Dyer, Lisa M; Kepple, Jessica D; Ai, Lingbao; Kim, Wan-Ju; Stanton, Virginia L; Reinhard, Mary K; Backman, Lindsey R F; Streitfeld, W Scott; Babu, Nivetha Ramesh; Treiber, Nicolai; Scharffetter-Kochanek, Karin; McKinnon, Peter J; Brown, Kevin D

    2017-12-01

    ATM activates the NF-κB transcriptional complex in response to genotoxic and oxidative stress. The purpose of this study was to examine if the NF-κB target gene and critical antioxidant SOD2 (MnSOD) in cultured mammary epithelium is also ATM-dependent, and what phenotypes arise from deletion of ATM and SOD2 within the mammary gland. SOD2 expression was studied in human mammary epithelial cells and MCF10A using RNAi to knockdown ATM or the NF-κB subunit RelA. To study ATM and SOD2 function in mammary glands, mouse lines containing Atm or Sod2 genes containing LoxP sites were mated with mice harboring Cre recombinase under the control of the whey acidic protein promoter. Quantitative PCR was used to measure gene expression, and mammary gland structure was studied using histology. SOD2 expression is ATM- and RelA-dependent, ATM knockdown renders cells sensitive to pro-oxidant exposure, and SOD mimetics partially rescue this sensitivity. Mice with germline deletion of Atm fail to develop mature mammary glands, but using a conditional knockout approach, we determined that Atm deletion significantly diminished the expression of Sod2. We also observed that these mice (termed Atm Δ/Δ ) displayed a progressive lactation defect as judged by reduced pup growth rate, aberrant lobulo-alveolar structure, diminished milk protein gene expression, and increased apoptosis within lactating glands. This phenotype appears to be linked to dysregulated Sod2 expression as mammary gland-specific deletion of Sod2 phenocopies defects observed in Atm Δ/Δ dams. We conclude that ATM is required to promote expression of SOD2 within the mammary epithelium, and that both ATM and SOD2 play a crucial role in mammary gland homeostasis.

  20. ATM Protein Physically and Functionally Interacts with Proliferating Cell Nuclear Antigen to Regulate DNA Synthesis*

    Science.gov (United States)

    Gamper, Armin M.; Choi, Serah; Matsumoto, Yoshihiro; Banerjee, Dibyendu; Tomkinson, Alan E.; Bakkenist, Christopher J.

    2012-01-01

    Ataxia telangiectasia (A-T) is a pleiotropic disease, with a characteristic hypersensitivity to ionizing radiation that is caused by biallelic mutations in A-T mutated (ATM), a gene encoding a protein kinase critical for the induction of cellular responses to DNA damage, particularly to DNA double strand breaks. A long known characteristic of A-T cells is their ability to synthesize DNA even in the presence of ionizing radiation-induced DNA damage, a phenomenon termed radioresistant DNA synthesis. We previously reported that ATM kinase inhibition, but not ATM protein disruption, blocks sister chromatid exchange following DNA damage. We now show that ATM kinase inhibition, but not ATM protein disruption, also inhibits DNA synthesis. Investigating a potential physical interaction of ATM with the DNA replication machinery, we found that ATM co-precipitates with proliferating cell nuclear antigen (PCNA) from cellular extracts. Using bacterially purified ATM truncation mutants and in vitro translated PCNA, we showed that the interaction is direct and mediated by the C terminus of ATM. Indeed, a 20-amino acid region close to the kinase domain is sufficient for strong binding to PCNA. This binding is specific to ATM, because the homologous regions of other PIKK members, including the closely related kinase A-T and Rad3-related (ATR), did not bind PCNA. ATM was found to bind two regions in PCNA. To examine the functional significance of the interaction between ATM and PCNA, we tested the ability of ATM to stimulate DNA synthesis by DNA polymerase δ, which is implicated in both DNA replication and DNA repair processes. ATM was observed to stimulate DNA polymerase activity in a PCNA-dependent manner. PMID:22362778

  1. Software engineering ethics

    Science.gov (United States)

    Bown, Rodney L.

    1991-01-01

    Software engineering ethics is reviewed. The following subject areas are covered: lack of a system viewpoint; arrogance of PC DOS software vendors; violation od upward compatibility; internet worm; internet worm revisited; student cheating and company hiring interviews; computing practitioners and the commodity market; new projects and old programming languages; schedule and budget; and recent public domain comments.

  2. Core Flight Software

    Data.gov (United States)

    National Aeronautics and Space Administration — The AES Core Flight Software (CFS) project purpose is to analyze applicability, and evolve and extend the reusability of the CFS system originally developed by...

  3. Core component integration tests for the back-end software sub-system in the ATLAS data acquisition and event filter prototype -1 project

    International Nuclear Information System (INIS)

    Badescu, E.; Caprini, M.; Niculescu, M.; Radu, A.

    2000-01-01

    The ATLAS data acquisition (DAQ) and Event Filter (EF) prototype -1 project was intended to produce a prototype system for evaluating candidate technologies and architectures for the final ATLAS DAQ system on the LHC accelerator at CERN. Within the prototype project, the back-end sub-system encompasses the software for configuring, controlling and monitoring the DAQ. The back-end sub-system includes core components and detector integration components. The core components provide the basic functionality and had priority in terms of time-scale for development in order to have a baseline sub-system that can be used for integration with the data-flow sub-system and event filter. The following components are considered to be the core of the back-end sub-system: - Configuration databases, describe a large number of parameters of the DAQ system architecture, hardware and software components, running modes and status; - Message reporting system (MRS), allows all software components to report messages to other components in the distributed environment; - Information service (IS) allows the information exchange for software components; - Process manager (PMG), performs basic job control of software components (start, stop, monitoring the status); - Run control (RC), controls the data taking activities by coordinating the operations of the DAQ sub-systems, back-end software and external systems. Performance and scalability tests have been made for individual components. The back-end subsystem integration tests bring together all the core components and several trigger/DAQ/detector integration components to simulate the control and configuration of data taking sessions. For back-end integration tests a test plan was provided. The tests have been done using a shell script that goes through different phases as follows: - starting the back-end server processes to initialize communication services and PMG; - launching configuration specific processes via DAQ supervisor as

  4. Status Report on the Development of Micro-Scheduling Software for the Advanced Outage Control Center Project

    Energy Technology Data Exchange (ETDEWEB)

    Germain, Shawn St. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Thomas, Kenneth [Idaho National Lab. (INL), Idaho Falls, ID (United States); Farris, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    The long-term viability of existing nuclear power plants (NPPs) in the United States (U.S.) is dependent upon a number of factors, including maintaining high capacity factors, maintaining nuclear safety, and reducing operating costs, particularly those associated with refueling outages. Refueling outages typically take 20-30 days, and for existing light water NPPs in the U.S., the reactor cannot be in operation during the outage. Furthermore, given that many NPPs generate between $1-1.5 million/day in revenue when in operation, there is considerable interest in shortening the length of refueling outages. Yet, refueling outages are highly complex operations, involving multiple concurrent and dependent activities that are difficult to coordinate. Finding ways to improve refueling outage performance while maintaining nuclear safety has proven to be difficult. The Advanced Outage Control Center project is a research and development (R&D) demonstration activity under the Light Water Reactor Sustainability (LWRS) Program. LWRS is a R&D program which works with industry R&D programs to establish technical foundations for the licensing and managing of long-term, safe, and economical operation of current NPPs. The Advanced Outage Control Center project has the goal of improving the management of commercial NPP refueling outages. To accomplish this goal, this INL R&D project is developing an advanced outage control center (OCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. This report describes specific recent efforts to develop a capability called outage Micro-Scheduling. Micro-Scheduling is the ability to allocate and schedule outage support task resources on a sub-hour basis. Micro-Scheduling is the real-time fine-tuning of the outage schedule to react to the actual progress of the primary outage activities to ensure that support task resources are

  5. ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2).

    Science.gov (United States)

    Jiang, Y; Chen, H-C; Su, X; Thompson, P A; Liu, X; Do, K-A; Wierda, W; Keating, M J; Plunkett, W

    2016-09-02

    Approximately 10-20% of chronic lymphocytic leukemia (CLL) patients exhibit del(11q22-23) before treatment, this cohort increases to over 40% upon progression following chemoimmunotherapy. The coding sequence of the DNA damage response gene, ataxia-telangiectasia-mutated (ATM), is contained in this deletion. The residual ATM allele is frequently mutated, suggesting a relationship between gene function and clinical response. To investigate this possibility, we sought to develop and validate an assay for the function of ATM protein in these patients. SMC1 (structural maintenance of chromosomes 1) and KAP1 (KRAB-associated protein 1) were found to be unique substrates of ATM kinase by immunoblot detection following ionizing radiation. Using a pool of eight fluorescence in situ hybridization-negative CLL samples as a standard, the phosphorylation of SMC1 and KAP1 from 46 del (11q22-23) samples was analyzed using normal mixture model-based clustering. This identified 13 samples (28%) that were deficient in ATM function. Targeted sequencing of the ATM gene of these samples, with reference to genomic DNA, revealed 12 somatic mutations and 15 germline mutations in these samples. No strong correlation was observed between ATM mutation and function. Therefore, mutation status may not be taken as an indicator of ATM function. Rather, a direct assay of the kinase activity should be used in the development of therapies.

  6. NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.

    Science.gov (United States)

    Adamowicz, Marek; Vermezovic, Jelena; d'Adda di Fagagna, Fabrizio

    2016-08-23

    The DNA damage response (DDR) signal transduction pathway is responsible for sensing DNA damage and further relaying this signal into the cell. ATM is an apical DDR kinase that orchestrates the activation and the recruitment of downstream DDR factors to induce cell-cycle arrest and repair. We have previously shown that NOTCH1 inhibits ATM activation upon DNA damage, but the underlying mechanism remains unclear. Here, we show that NOTCH1 does not impair ATM recruitment to DNA double-strand breaks (DSBs). Rather, NOTCH1 prevents binding of FOXO3a and KAT5/Tip60 to ATM through a mechanism in which NOTCH1 competes with FOXO3a for ATM binding. Lack of FOXO3a binding to ATM leads to the loss of KAT5/Tip60 association with ATM. Moreover, expression of NOTCH1 or depletion of ATM impairs the formation of the FOXO3a-KAT5/Tip60 protein complex. Finally, we show that pharmacological induction of FOXO3a nuclear localization sensitizes NOTCH1-driven cancers to DNA-damage-induced cell death. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Simultaneous depletion of Atm and Mdl rebalances cytosolic Fe-S cluster assembly but not heme import into the mitochondrion of Trypanosoma brucei

    Czech Academy of Sciences Publication Activity Database

    Horáková, Eva; Changmai, Piya; Paris, Zdeněk; Salmon, D.; Lukeš, Julius

    2015-01-01

    Roč. 282, č. 21 (2015), s. 4157-4175 ISSN 1742-464X R&D Projects: GA ČR(CZ) GAP305/11/2179; GA ČR GJ15-21450Y; GA MŠk LH12104 EU Projects: European Commission(XE) 316304 Institutional support: RVO:60077344 Keywords : Atm * Fe-S cluster * heme * Mdl * Trypanosoma Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.237, year: 2015

  8. Fabrication and characterization of MCC approved testing material - ATM-1 glass

    International Nuclear Information System (INIS)

    Wald, J.W.

    1985-10-01

    The Materials Characterization Center Approved Testing Material ATM-1 is a borosilicate glass that incorporates nonradioactive constituents and uranium to represent high-level waste (HLW) resulting from the reprocessing of commercial nuclear reactor fuel. Its composition is based upon the simulated HLW glass type 76-68 to which depleted uranium has been added as UO 2 . Three separate lots of ATM-1 glass have been fabricated, designated ATM-1a, ATM-1b, and ATM-1c. Limited analyses and microstructural evaluations were conducted on each type. Each lot of ATM-1 glass was produced from a feedstock melted in an air atmosphere at between 1150 to 1200 0 C and cast into stress annealed rectangular bars. Bars of ATM-1a were nominally 1.3 x 1.3 x 7.6 cm (approx.36 g each), bars of ATM-1b were nominally 2 x 2.5 x 17.5 cm (approx.190 g each) and bars of ATM-1c were nominally 1.9 x 1.9 x 15 cm (approx.170 g each). Thirteen bars of ATM-1a, 14 bars of ATM-1b, and 6 bars of ATM-1c were produced. Twelve random samples from each of lots ATM-1a, ATM-1b, and ATM-1c were analyzed. The concentrations (except for U and Cs) were obtained by Inductively-Coupled Argon Plasma Atomic Emission Spectroscopy analysis. Cesium analysis was performed by Atomic Absorption Spectroscopy, while uranium was analyzed by Pulsed Laser Fluorometry. X-ray diffraction analysis of four samples indicated that lot ATM-1a had no detectable crystalline phases (<3 wt %), while ATM-1b and ATM-1c contained approx.3 to 5 wt % iron-chrome spinel crystals. These concentrations of secondary spinel component are not considered uncommon. Scanning electron microscopy examination of fracture surfaces revealed only a random, apparently crystalline, second phase (1-10 μm diam) and a random distribution of small voids or bubbles (approx.1 μm nominal diam)

  9. Simultaneous ATM/BRCA1/RAD51 expression variations associated with prognostic factors in Iranian sporadic breast cancer patients.

    Science.gov (United States)

    Hallajian, Zeinab; Mahjoubi, Frouzandeh; Nafissi, Nahid

    2017-07-01

    DNA double-strand breaks (DSBs) as a serious lesion are repaired by non-homologous end-joining and homologous recombination pathways. ATM, BRCA1, RAD51 genes are involved in HR pathways. While some studies have revealed individual expression changes of these genes in different types of cancer, there are limited studies attempting to evaluate correlation of expression variations of these genes in breast cancer pathogenesis. This study aimed to determine RAD51, ATM and BRCA1 gene expression level and its association with clinicopathological factors in fresh breast cancer tissues. Moreover, this study evaluates potential correlations among expression levels of these genes. 50 breast cancer tissues were collected and examined for BRCA1, RAD51 and ATM gene expression by Real Time PCR. Expression changes were analyzed with REST software version 2009. mRNA expression was reduced in all these three genes when compared with β-Actin as a control gene (P value  ATM, BRCA1 and RAD51 gene down expression (P value  ATM with stage (P value  < 0.05), necrosis (P value  < 0.05), perineural invasion (P value  < 0.05), vascular invasion (P value  < 0.01), malignancy (P value  ≤ 0.001), PR (P value  < 0.05) and ER status (P value  < 0.01). In addition, there was a significant association between down expression of BRCA1 with Ki67 (P value  ≤ 0.001). Moreover, there was a significant association between down expression of RAD51 with lymph node involvement (P value  < 0.01), auxiliary lymph node metastasis (P value  = 0.01), age (P = 0.001), grade (P value  < 0.05) and PR status (P value  < 0.05). This study suggests association between expression changes in several DSB repair genes in a common functional pathway in breast cancer and the significant association between abnormal expression of these genes and important clinical prognostic factors.

  10. ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.

    Science.gov (United States)

    Drosos, Yiannis; Escobar, David; Chiang, Ming-Yi; Roys, Kathryn; Valentine, Virginia; Valentine, Marc B; Rehg, Jerold E; Sahai, Vaibhav; Begley, Lesa A; Ye, Jianming; Paul, Leena; McKinnon, Peter J; Sosa-Pineda, Beatriz

    2017-09-11

    Germline mutations in ATM (encoding the DNA-damage signaling kinase, ataxia-telangiectasia-mutated) increase Familial Pancreatic Cancer (FPC) susceptibility, and ATM somatic mutations have been identified in resected human pancreatic tumors. Here we investigated how Atm contributes to pancreatic cancer by deleting this gene in a murine model of the disease expressing oncogenic Kras (Kras G12D ). We show that partial or total ATM deficiency cooperates with Kras G12D to promote highly metastatic pancreatic cancer. We also reveal that ATM is activated in pancreatic precancerous lesions in the context of DNA damage and cell proliferation, and demonstrate that ATM deficiency leads to persistent DNA damage in both precancerous lesions and primary tumors. Using low passage cultures from primary tumors and liver metastases we show that ATM loss accelerates Kras-induced carcinogenesis without conferring a specific phenotype to pancreatic tumors or changing the status of the tumor suppressors p53, p16 Ink4a and p19 Arf . However, ATM deficiency markedly increases the proportion of chromosomal alterations in pancreatic primary tumors and liver metastases. More importantly, ATM deficiency also renders murine pancreatic tumors highly sensitive to radiation. These and other findings in our study conclusively establish that ATM activity poses a major barrier to oncogenic transformation in the pancreas via maintaining genomic stability.

  11. Downregulation of ATM Gene and Protein Expression in Canine Mammary Tumors.

    Science.gov (United States)

    Raposo-Ferreira, T M M; Bueno, R C; Terra, E M; Avante, M L; Tinucci-Costa, M; Carvalho, M; Cassali, G D; Linde, S D; Rogatto, S R; Laufer-Amorim, R

    2016-11-01

    The ataxia telangiectasia mutated (ATM) gene encodes a protein associated with DNA damage repair and maintenance of genomic integrity. In women, ATM transcript and protein downregulation have been reported in sporadic breast carcinomas, and the absence of ATM protein expression has been associated with poor prognosis. The aim of this study was to evaluate ATM gene and protein expression in canine mammary tumors and their association with clinical outcome. ATM gene and protein expression was evaluated by reverse transcription-quantitative polymerase chain reaction and immunohistochemistry, respectively, in normal mammary gland samples (n = 10), benign mammary tumors (n = 11), nonmetastatic mammary carcinomas (n = 19), and metastatic mammary carcinomas (n = 11). Lower ATM transcript levels were detected in benign mammary tumors and carcinomas compared with normal mammary glands (P = .011). Similarly, lower ATM protein expression was observed in benign tumors (P = .0003), nonmetastatic mammary carcinomas (P ATM gene or protein levels were detected among benign tumors and nonmetastatic and metastatic mammary carcinomas (P > .05). The levels of ATM gene or protein expression were not significantly associated with clinical and pathological features or with survival. Similar to human breast cancer, the data in this study suggest that ATM gene and protein downregulation is involved in canine mammary gland tumorigenesis. © The Author(s) 2016.

  12. Neurodegeneration in ataxia-telangiectasia: Multiple roles of ATM kinase in cellular homeostasis.

    Science.gov (United States)

    Choy, Kay Rui; Watters, Dianne J

    2018-01-01

    Ataxia-telangiectasia (A-T) is characterized by neuronal degeneration, cancer, diabetes, immune deficiency, and increased sensitivity to ionizing radiation. A-T is attributed to the deficiency of the protein kinase coded by the ATM (ataxia-telangiectasia mutated) gene. ATM is a sensor of DNA double-strand breaks (DSBs) and signals to cell cycle checkpoints and the DNA repair machinery. ATM phosphorylates numerous substrates and activates many cell-signaling pathways. There has been considerable debate about whether a defective DNA damage response is causative of the neurological aspects of the disease. In proliferating cells, ATM is localized mainly in the nucleus; however, in postmitotic cells such as neurons, ATM is mostly cytoplasmic. Recent studies reveal an increasing number of roles for ATM in the cytoplasm, including activation by oxidative stress. ATM associates with organelles including mitochondria and peroxisomes, both sources of reactive oxygen species (ROS), which have been implicated in neurodegenerative diseases and aging. ATM is also associated with synaptic vesicles and has a role in regulating cellular homeostasis and autophagy. The cytoplasmic roles of ATM provide a new perspective on the neurodegenerative process in A-T. This review will examine the expanding roles of ATM in cellular homeostasis and relate these functions to the complex A-T phenotype. Developmental Dynamics 247:33-46, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  13. Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

    Science.gov (United States)

    Zhou, Yi; Lee, Ji-Hoon; Jiang, Wenxia; Crowe, Jennie L; Zha, Shan; Paull, Tanya T

    2017-01-05

    Ataxia-telangiectasia mutated (ATM) regulates the DNA damage response as well as DNA double-strand break repair through homologous recombination. Here we show that ATM is hyperactive when the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is chemically inhibited or when the DNA-PKcs gene is deleted in human cells. Pre-incubation of ATM protein with active DNA-PKcs also significantly reduces ATM activity in vitro. We characterize several phosphorylation sites in ATM that are targets of DNA-PKcs and show that phospho-mimetic mutations at these residues significantly inhibit ATM activity and impair ATM signaling upon DNA damage. In contrast, phospho-blocking mutations at one cluster of sites increase the frequency of apoptosis during normal cell growth. DNA-PKcs, which is integral to the non-homologous end joining pathway, thus negatively regulates ATM activity through phosphorylation of ATM. These observations illuminate an important regulatory mechanism for ATM that also controls DNA repair pathway choice. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Molecular and functional characterization of a human ATM gene analogue at Arabidopsis thaliana

    International Nuclear Information System (INIS)

    Garcia, V.

    2001-12-01

    The human ATM gene, whose inactivation is responsible for the human disease ataxia telangiectasia is conserved throughout the Eukaryotes and plays an important role in the cellular responses to DNA damage, in particular to DNA double-strand breaks (DSBs). Here we describe the identification of an Arabidopsis thaliana homologue of ATM (AtATM), and the molecular and cytological characterization of plants, hereafter called atm, carrying a disrupting T-DNA insertion in this gene. AtATM covers a 32 kb region on chromosome 3. The AtATM transcript has a complex structure, is 12 kb long and formed by 79 exons. The transcriptional level of AtATM is very low in all the tissues tested, and does not vary after exposure to ionizing radiations (IR). In atm plants, the protein is not detected suggesting the mutants are null. The atm mutants are partially sterile. Aberrant segregation of chromosomes during meiosis I on both male and female sides account for this sterility. However, meiotic recombination frequency is normal. Mutant plants are also hypersensitive to gamma rays and methyl methane sulfonate, but not to UV-B, pointing to a specific defect of atm mutants in the response to DNA DSBs. In plants, ionizing radiations induce a strong, rapid and transient transcriptional activation of genes involved in the cellular response to or the repair of DSBs. This transcriptional regulation of AtRAD51, AtPARP1, atGR1 and AtL1G4 is lost in the atm mutants . The absence of AtRAD51 induction associated with ionizing radiation sensitivity suggest that AtAtm play an important function in DSB repair by homologous recombination. In addition we show that homologous intra-chromosomal recombination frequency is elevated in the mutant comparing to wild-type, with or without gamma irradiation. These results show the implication of AtAtm in the genomic stability. (author)

  15. Collected software engineering papers, volume 2

    Science.gov (United States)

    1983-01-01

    Topics addressed include: summaries of the software engineering laboratory (SEL) organization, operation, and research activities; results of specific research projects in the areas of resource models and software measures; and strategies for data collection for software engineering research.

  16. Essence: Facilitating Software Innovation

    DEFF Research Database (Denmark)

    Aaen, Ivan

    2008-01-01

      This paper suggests ways to facilitate creativity and innovation in software development. The paper applies four perspectives – Product, Project, Process, and People –to identify an outlook for software innovation. The paper then describes a new facility–Software Innovation Research Lab (SIRL......) – and a new method concept for software innovation – Essence – based on views, modes, and team roles. Finally, the paper reports from an early experiment using SIRL and Essence and identifies further research....

  17. Global Software Engineering

    DEFF Research Database (Denmark)

    Ebert, Christof; Kuhrmann, Marco; Prikladnicki, Rafael

    2016-01-01

    Professional software products and IT systems and services today are developed mostly by globally distributed teams, projects, and companies. Successfully orchestrating Global Software Engineering (GSE) has become the major success factor both for organizations and practitioners. Yet, more than...... and experience reported at the IEEE International Conference on Software Engineering (ICGSE) series. The outcomes of our analysis show GSE as a field highly attached to industry and, thus, a considerable share of ICGSE papers address the transfer of Software Engineering concepts and solutions to the global stage...

  18. The Art of Software Testing

    CERN Document Server

    Myers, Glenford J; Badgett, Tom

    2011-01-01

    The classic, landmark work on software testing The hardware and software of computing have changed markedly in the three decades since the first edition of The Art of Software Testing, but this book's powerful underlying analysis has stood the test of time. Whereas most books on software testing target particular development techniques, languages, or testing methods, The Art of Software Testing, Third Edition provides a brief but powerful and comprehensive presentation of time-proven software testing approaches. If your software development project is mission critical, this book is an investme

  19. Software Project Management Plan for the Integrated Systems Code (ISC) of New Production Reactor -- Modular High Temperature Gas Reactor

    International Nuclear Information System (INIS)

    Taylor, D.

    1990-11-01

    The United States Department of Energy (DOE) has selected the Modular High Temperature Gas-Cooled Reactor (MHTGR) as one of the concepts for the New Production Reactor (NPR). DOE has also established several Technical Working Groups (TWG's) at the national laboratories to provide independent design confirmation of the NPR-MHTGR design. One of those TWG's is concerned with Thermal Fluid Flow (TFF) and analysis methods to provide independent design confirmation of the NPR-MHTGR. Analysis methods are also needed for operational safety evaluations, performance monitoring, sensitivity studies, and operator training. The TFF Program Plan includes, as one of its principal tasks, the development of a computer program (called the Integrated Systems Code, or ISC). This program will provide the needed long-term analysis capabilities for the MHTGR and its subsystems. This document presents the project management plan for development of the ISC. It includes the associated quality assurance tasks, and the schedule and resource requirements to complete these activities. The document conforms to the format of ANSI/IEEE Std. 1058.1-1987. 2 figs

  20. GENII (Generation II): The Hanford Environmental Radiation Dosimetry Software System: Volume 3, Code maintenance manual: Hanford Environmental Dosimetry Upgrade Project

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.; Ramsdell, J.V.

    1988-09-01

    The Hanford Environmental Dosimetry Upgrade Project was undertaken to incorporate the internal dosimetry models recommended by the International Commission on Radiological Protection (ICRP) in updated versions of the environmental pathway analysis models used at Hanford. The resulting second generation of Hanford environmental dosimetry computer codes is compiled in the Hanford Environmental Dosimetry System (Generation II, or GENII). This coupled system of computer codes is intended for analysis of environmental contamination resulting from acute or chronic releases to, or initial contamination of, air, water, or soil, on through the calculation of radiation doses to individuals or populations. GENII is described in three volumes of documentation. This volume is a Code Maintenance Manual for the serious user, including code logic diagrams, global dictionary, worksheets to assist with hand calculations, and listings of the code and its associated data libraries. The first volume describes the theoretical considerations of the system. The second volume is a Users' Manual, providing code structure, users' instructions, required system configurations, and QA-related topics. 7 figs., 5 tabs.