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Sample records for asymmetrical flow field-flow

  1. Analysis of liposomes using asymmetrical flow field-flow fractionation

    DEFF Research Database (Denmark)

    Kuntsche, Judith; Decker, Christiane; Fahr, Alfred

    2012-01-01

    Liposomes composed of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol were analyzed by asymmetrical flow field-flow fractionation coupled with multi-angle laser light scattering. In addition to evaluation of fractionation conditions (flow conditions, sample mass, carrier liquid...

  2. Efficient algorithms for Asymmetric Flow Field Flow Fractionation

    OpenAIRE

    Nagapetyan, Tigran

    2014-01-01

    This thesis is devoted to the modeling and simulation of Asymmetric Flow Field Flow Fractionation, which is a technique for separating particles of submicron scale. This process is a part of large family of Field Flow Fractionation techniques and has a very broad range of industrial applications, e. g. in microbiology, chemistry, pharmaceutics, environmental analysis. Mathematical modeling is crucial for this process, as due to the own nature of the process, lab ex- periments are difficult...

  3. Asymmetric flow field-flow fractionation of (bio) macromolecules (abstract)

    International Nuclear Information System (INIS)

    Field-Flow Fractionation (FFF) has developed into a promising separation technique with different variants in various applications fields of separation sciences. Asymmetric Flow FFF (FlFFF) is the most popular class of the FFF family; it is used for the separation and characterization of nano- to micro-sized particles of diverse origin. It is simple, gentle and soft separation principle is most feasible for fragile macromolecules present in biological samples. Although recently there has been a substantial involvement of asymmetric FlFFF for the characterization of proteins, viruses, DNA and cells, its application for body fluid analysis in clinical laboratories has yet to be explored. The purpose of the research study was to explore asymmetric FlFFF as an analytical tool for the analysis of (bio) macromolecules, especially in clinical perspective and to see how much the results based on its use are beneficent in diagnostic studies of various diseases. Different approaches involving asymmetric FlFFF prior to renowned separating techniques such as liquid and gas chromatography are exploited, to get additional insights in (bio) macromolecules based on their size. The research work was focused on human serum analysis, to characterize lipoproteins and their associated compounds, which could add more information in diagnosing coronary heart diseases. Furthermore, the size-based separation of blood circulating hyaluronan was studied, which could provide a vital clue in understanding the metabolic activity of endothelial glyco calyx under pathological conditions. (author)

  4. Characterization of enzymatically synthesized amylopectin analogs via asymmetrical flow field flow fractionation

    NARCIS (Netherlands)

    Ciric, Jelena; Rolland-Sabate, Agnes; Guilois, Sophie; Loos, Katja

    2014-01-01

    Asymmetrical flow field flow fractionation (AF4), when coupled with multi-angle laser light scattering (MALLS), is a very powerful technique for determination of the macromolecular structure of high molar mass (branched) polysaccharides. AF4 is a size fractionation technique just as size exclusion c

  5. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    OpenAIRE

    David eMüller; Stefano eCattaneo; Florian eMeier; Roland eWelz; deMello, Andrew J.

    2015-01-01

    Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the scale-down platform ...

  6. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    OpenAIRE

    Müller, David; Cattaneo, Stefano; Meier, Florian; Welz, Roland; de Mello, Andrew J.

    2015-01-01

    Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the down-scaled platform...

  7. Determination of the functioning parameters in asymmetrical flow field-flow fractionation with an exponential channel.

    Science.gov (United States)

    Déjardin, P

    2013-08-30

    The flow conditions in normal mode asymmetric flow field-flow fractionation are determined to approach the high retention limit with the requirement d≪l≪w, where d is the particle diameter, l the characteristic length of the sample exponential distribution and w the channel height. The optimal entrance velocity is determined from the solute characteristics, the channel geometry (exponential to rectangular) and the membrane properties, according to a model providing the velocity fields all over the cell length. In addition, a method is proposed for in situ determination of the channel height. PMID:23885667

  8. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    Directory of Open Access Journals (Sweden)

    David eMüller

    2015-07-01

    Full Text Available Asymmetrical Flow Field-Flow Fractionation (AF4 is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the scale-down platform include simplified cartridge and reagent handling, reduced analysis costs and higher throughput capacities. The separation performance of the miniaturized cartridge is assessed using certified gold and silver nanoparticle standards. Analysis of gold nanoparticle populations indicates shorter analysis times and increased sensitivity compared to conventional AF4 separation schemes. Moreover, nanoparticulate titanium dioxide populations exhibiting broad size distributions are analyzed in a rapid and efficient manner. Finally, the repeatability and reproducibility of the miniaturized platform are investigated with respect to analysis time and separation efficiency.

  9. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge.

    Science.gov (United States)

    Müller, David; Cattaneo, Stefano; Meier, Florian; Welz, Roland; de Mello, Andrew J

    2015-01-01

    Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the down-scaled platform include simplified cartridge and reagent handling, reduced analysis costs and higher throughput capacities. The separation performance of the miniaturized cartridge is assessed using certified gold and silver nanoparticle standards. Analysis of gold nanoparticle populations indicates shorter analysis times and increased sensitivity compared to conventional AF4 separation schemes. Moreover, nanoparticulate titanium dioxide populations exhibiting broad size distributions are analyzed in a rapid and efficient manner. Finally, the repeatability and reproducibility of the miniaturized platform are investigated with respect to analysis time and separation efficiency. PMID:26258119

  10. Factors affecting measurement of channel thickness in asymmetrical flow field-flow fractionation.

    Science.gov (United States)

    Dou, Haiyang; Jung, Euo Chang; Lee, Seungho

    2015-05-01

    Asymmetrical flow field-flow fractionation (AF4) has been considered to be a useful tool for simultaneous separation and characterization of polydisperse macromolecules or colloidal nanoparticles. AF4 analysis requires the knowledge of the channel thickness (w), which is usually measured by injecting a standard with known diffusion coefficient (D) or hydrodynamic diameter (dh). An accurate w determination is a challenge due to its uncertainties arising from the membrane's compressibility, which may vary with experimental condition. In the present study, influence of factors including the size and type of the standard on the measurement of w was systematically investigated. The results revealed that steric effect and the particles-membrane interaction by van der Waals or electrostatic force may result in an error in w measurement. PMID:25817708

  11. Rational strategy for characterization of nanoscale particles by asymmetric-flow field flow fractionation: a tutorial.

    Science.gov (United States)

    Gigault, Julien; Pettibone, John M; Schmitt, Charlène; Hackley, Vincent A

    2014-01-27

    This tutorial proposes a comprehensive and rational measurement strategy that provides specific guidance for the application of asymmetric-flow field flow fractionation (A4F) to the size-dependent separation and characterization of nanoscale particles (NPs) dispersed in aqueous media. A range of fractionation conditions are considered, and challenging applications, including industrially relevant materials (e.g., metal NPs, asymmetric NPs), are utilized in order to validate and illustrate this approach. We demonstrate that optimization is material dependent and that polystyrene NPs, widely used as a reference standard for retention calibration in A4F, in fact represent a class of materials with unique selectivity, recovery and optimal conditions for fractionation; thus use of these standards to calibrate retention for other materials must be validated a posteriori. We discuss the use and relevance of different detection modalities that can potentially yield multi-dimensional and complementary information on NP systems. We illustrate the fractionation of atomically precise nanoclusters, which are the lower limit of the nanoscale regime. Conversely, we address the upper size limit for normal mode elution in A4F. The protocol for A4F fractionation, including the methods described in the present work is proposed as a standardized strategy to realize interlaboratory comparability and to facilitate the selection and validation of material-specific measurement parameters and conditions. It is intended for both novice and advanced users of this measurement technology. PMID:24418128

  12. Asymmetrical flow field-flow fractionation with on-line detection for drug transfer studies: a feasibility study

    DEFF Research Database (Denmark)

    Hinna, A.; Steiniger, F.; Hupfeld, S.; Brandl, M.; Kuntsche, J.

    2014-01-01

    Knowledge about drug retention within colloidal carriers is of uppermost importance particularly if drug targeting is anticipated. The aim of the present study was to evaluate asymmetrical flow field-flow fractionation (AF4) with on-line UV/VIS drug quantification for its suitability to determine...

  13. Size characterization and quantification of exosomes by asymmetrical-flow field-flow fractionation.

    Science.gov (United States)

    Sitar, Simona; Kejžar, Anja; Pahovnik, David; Kogej, Ksenija; Tušek-Žnidarič, Magda; Lenassi, Metka; Žagar, Ema

    2015-09-15

    In the past few years extracellular vesicles called exosomes have gained huge interest of scientific community since they show a great potential for human diagnostic and therapeutic applications. However, an ongoing challenge is accurate size characterization and quantification of exosomes because of the lack of reliable characterization techniques. In this work, the emphasis was focused on a method development to size-separate, characterize, and quantify small amounts of exosomes by asymmetrical-flow field-flow fractionation (AF4) technique coupled to a multidetection system (UV and MALS). Batch DLS (dynamic light-scattering) and NTA (nanoparticle tracking analysis) analyses of unfractionated exosomes were also conducted to evaluate their shape and internal structure, as well as their number density. The results show significant influence of cross-flow conditions and channel thickness on fractionation quality of exosomes, whereas the focusing time has less impact. The AF4/UV-MALS and DLS results display the presence of two particles subpopulations, that is, the larger exosomes and the smaller vesicle-like particles, which coeluted in AF4 together with impurities in early eluting peak. Compared to DLS and AF4-MALS results, NTA somewhat overestimates the size and the number density for larger exosome population, but it discriminates the smaller particle population. PMID:26291637

  14. Asymmetrical flow field-flow fractionation for the analysis of PEG-asparaginase.

    Science.gov (United States)

    John, C; Herz, T; Boos, J; Langer, K; Hempel, G

    2016-01-01

    Monomethoxypolyethylene glycol L-asparaginase (PEG-ASNASE) is the PEGylated version of the enzyme L-asparaginase (ASNASE). Both are used for remission induction in acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL). The treatment control is generally carried out by performing activity assays, though methods to determine the actual enzyme rather than its activity are rare. Using asymmetrical flow field-flow fractionation (AF4) offered the chance to develop a method capable of simultaneously measuring PEG-ASNASE and PEG. A method validation was performed in accordance with FDA guidelines for PEG-ASNASE from non-biological solutions. The method unfolded a linearity of 15-750 U/mL with coefficients of correlation of r(2)>0.99. The coefficients of variation (CV) for within-run and between-run variability were 1.18-10.15% and 2.43-8.73%, respectively. Furthermore, the method was used to perform stability tests of the product Oncaspar® (PEG-ASNASE) and estimation of the molecular weight by multi-angle light scattering (MALS) of stressed samples to correlate them with the corresponding activity. The findings indicate that Oncaspar® stock solution should not be stored any longer than 24 h at room temperature and cannot be frozen in pure aqueous media. The validated method might be useful for the pharmaceutical industry and its quality control of PEG-ASNASE production. PMID:26695272

  15. Rational strategy for characterization of nanoscale particles by asymmetric-flow field flow fractionation: A tutorial

    International Nuclear Information System (INIS)

    Graphical abstract: -- Highlights: •Underlying theory and critical parameters are introduced. •A rational workflow is proposed to optimize and refine A4F methods. •Specific optimization steps and validation parameters are delineated. •Pedagogical examples are provided to demonstrate the process. •Use and relevance of different detection modalities is addressed. -- Abstract: This tutorial proposes a comprehensive and rational measurement strategy that provides specific guidance for the application of asymmetric-flow field flow fractionation (A4F) to the size-dependent separation and characterization of nanoscale particles (NPs) dispersed in aqueous media. A range of fractionation conditions are considered, and challenging applications, including industrially relevant materials (e.g., metal NPs, asymmetric NPs), are utilized in order to validate and illustrate this approach. We demonstrate that optimization is material dependent and that polystyrene NPs, widely used as a reference standard for retention calibration in A4F, in fact represent a class of materials with unique selectivity, recovery and optimal conditions for fractionation; thus use of these standards to calibrate retention for other materials must be validated a posteriori. We discuss the use and relevance of different detection modalities that can potentially yield multi-dimensional and complementary information on NP systems. We illustrate the fractionation of atomically precise nanoclusters, which are the lower limit of the nanoscale regime. Conversely, we address the upper size limit for normal mode elution in A4F. The protocol for A4F fractionation, including the methods described in the present work is proposed as a standardized strategy to realize interlaboratory comparability and to facilitate the selection and validation of material-specific measurement parameters and conditions. It is intended for both novice and advanced users of this measurement technology

  16. Retention ratio and nonequilibrium bandspreading in asymmetrical flow field-flow fractionation.

    Science.gov (United States)

    Williams, P Stephen

    2015-06-01

    In asymmetrical flow field-flow fractionation (As-FlFFF), only the membrane-covered accumulation wall is permeable to fluid; the opposite channel wall is impermeable. Fluid enters the channel at the inlet and exits partly through the membrane-covered accumulation wall and partly through the channel outlet. This means that not only does the volumetric channel flow rate decrease along the channel length as fluid exits through the membrane but also the cross-channel component to fluid velocity must approach zero at the impermeable wall. This dependence of cross-channel fluid velocity on distance across the channel thickness influences the equilibrium concentration profile for the sample components introduced to the channel. The concentration profile departs from the exponential profile predicted for the ideal model of field-flow fractionation. This influences both the retention ratio and the principal contribution to bandspreading--the nonequilibrium contribution. The derivation of an equation for the nonequilibrium bandspreading parameter χ in As-FlFFF is presented, and its numerical solution graphed. At high retention, it is shown that the solutions for both retention ratio R and χ converge on those for the ideal model, as expected. At lower levels of retention, the departures from the ideal model are significant, particularly for bandspreading. For example, at a level of retention corresponding to a retention parameter λ of 0.05, R is almost 4% higher than for the ideal model (0.28047 as compared to 0.27000) but the value of χ is almost 60% higher. The equations presented for both R and χ include a first-order correction for the finite size of the particles--the steric exclusion correction. These corrections are shown to be significant for particle sizes eluting well before steric inversion. For example, particles of half the inversion diameter are predicted to elute 25% slower and to show almost 40% higher bandspreading when steric effects are not accounted

  17. Optimization and evaluation of asymmetric flow field-flow fractionation of silver nanoparticles.

    Science.gov (United States)

    Loeschner, Katrin; Navratilova, Jana; Legros, Samuel; Wagner, Stephan; Grombe, Ringo; Snell, James; von der Kammer, Frank; Larsen, Erik H

    2013-01-11

    Asymmetric flow field-flow fractionation (AF(4)) in combination with on-line optical detection and mass spectrometry is one of the most promising methods for separation and quantification of nanoparticles (NPs) in complex matrices including food. However, to obtain meaningful results regarding especially the NP size distribution a number of parameters influencing the separation need to be optimized. This paper describes the development of a separation method for polyvinylpyrrolidone-stabilized silver nanoparticles (AgNPs) in aqueous suspension. Carrier liquid composition, membrane material, cross flow rate and spacer height were shown to have a significant influence on the recoveries and retention times of the nanoparticles. Focus time and focus flow rate were optimized with regard to minimum elution of AgNPs in the void volume. The developed method was successfully tested for injected masses of AgNPs from 0.2 to 5.0 μg. The on-line combination of AF(4) with detection methods including ICP-MS, light absorbance and light scattering was helpful because each detector provided different types of information about the eluting NP fraction. Differences in the time-resolved appearance of the signals obtained by the three detection methods were explained based on the physical origin of the signal. Two different approaches for conversion of retention times of AgNPs to their corresponding sizes and size distributions were tested and compared, namely size calibration with polystyrene nanoparticles (PSNPs) and calculations of size based on AF(4) theory. Fraction collection followed by transmission electron microscopy was performed to confirm the obtained size distributions and to obtain further information regarding the AgNP shape. Characteristics of the absorbance spectra were used to confirm the presence of non-spherical AgNP. PMID:23261297

  18. Quantum dot agglomerates in biological media and their characterization by asymmetrical flow field-flow fractionation.

    Science.gov (United States)

    Moquin, Alexandre; Neibert, Kevin D; Maysinger, Dusica; Winnik, Françoise M

    2015-01-01

    The molecular composition of the biological environment of nanoparticles influences their physical properties and changes their pristine physicochemical identity. In order to understand, or predict, the interactions of cells with specific nanoparticles, it is critical to know their size, shape, and agglomeration state not only in their nascent state but also in biological media. Here, we use asymmetrical flow field-flow fractionation (AF4) with on-line multiangle light scattering (MALS), dynamic light scattering (DLS) and UV-Visible absorption detections to determine the relative concentration of isolated nanoparticles and agglomerates in the case of three types of semi-conductor quantum dots (QDs) dispersed in Dulbecco's Modified Eagle Media (DMEM) containing 10% of fetal bovine serum (DMEM-FBS). AF4 analysis also yielded the size and size distribution of the agglomerates as a function of the time of QDs incubation in DMEM-FBS. The preferred modes of internalization of the QDs are assessed for three cell-types, N9 microglia, human hepatocellular carcinoma cells (HepG2) and human embryonic kidney cells (Hek293), by confocal fluorescence imaging of live cells, quantitative determination of the intracellular QD concentration, and flow cytometry. There is an excellent correlation between the agglomeration status of the three types of QDs in DMEM-FBS determined by AF4 analysis and their preferred mode of uptake by the three cell lines, which suggests that AF4 yields an accurate description of the nanoparticles as they encounter cells and advocates its use as a means to characterize particles under evaluation. PMID:25542679

  19. Separation and characterization of poly(tetrafluoroethylene) latex particles by asymmetric flow field flow fractionation with light-scattering detection.

    Science.gov (United States)

    Collins, Melissa E; Soto-Cantu, Erick; Cueto, Rafael; Russo, Paul S

    2014-04-01

    Poly(tetrafluoroethylene) (PTFE) latex particles have been analyzed and sorted according to size using asymmetric flow field flow fractionation (AF4) coupled with multiple-angle light scattering (MALS). Characterization of fractions by regular and depolarized dynamic light scattering confirmed that smaller particles elute prior to larger ones, as expected for field flow fractionation. The measured radii of the optically and geometrically anisotropic particles are consistent with those determined from transmission electron microscopy (TEM). A certain amount of heterogeneity remains in the fractions, but their uniformity for use as diffusion probes is improved. Full characterization of PTFE colloids will require a difficult assessment of the distribution, even within fractions, of the optical anisotropy. A general method to obtain number versus size distributions is presented. This approach is valid even when an online concentration detector is not available or ineffective. The procedure is adaptable to particles of almost any regular shape. PMID:24635125

  20. A critical evaluation of an asymmetrical flow field-flow fractionation system for colloidal size characterization of natural organic matter.

    Science.gov (United States)

    Zhou, Zhengzhen; Guo, Laodong

    2015-06-19

    Colloidal retention characteristics, recovery and size distribution of model macromolecules and natural dissolved organic matter (DOM) were systematically examined using an asymmetrical flow field-flow fractionation (AFlFFF) system under various membrane size cutoffs and carrier solutions. Polystyrene sulfonate (PSS) standards with known molecular weights (MW) were used to determine their permeation and recovery rates by membranes with different nominal MW cutoffs (NMWCO) within the AFlFFF system. Based on a ≥90% recovery rate for PSS standards by the AFlFFF system, the actual NMWCOs were determined to be 1.9 kDa for the 0.3 kDa membrane, 2.7 kDa for the 1 kDa membrane, and 33 kDa for the 10 kDa membrane, respectively. After membrane calibration, natural DOM samples were analyzed with the AFlFFF system to determine their colloidal size distribution and the influence from membrane NMWCOs and carrier solutions. Size partitioning of DOM samples showed a predominant colloidal size fraction in the flow field-flow fractionation technique. In addition, the coupling of AFlFFF with fluorescence EEMs could provide new insights into DOM heterogeneity in different colloidal size fractions. PMID:25958093

  1. Fractionating power and outlet stream polydispersity in asymmetrical flow field-flow fractionation. Part I: isocratic operation.

    Science.gov (United States)

    Williams, P Stephen

    2016-05-01

    Asymmetrical flow field-flow fractionation (As-FlFFF) has become the most commonly used of the field-flow fractionation techniques. However, because of the interdependence of the channel flow and the cross flow through the accumulation wall, it is the most difficult of the techniques to optimize, particularly for programmed cross flow operation. For the analysis of polydisperse samples, the optimization should ideally be guided by the predicted fractionating power. Many experimentalists, however, neglect fractionating power and rely on light scattering detection simply to confirm apparent selectivity across the breadth of the eluted peak. The size information returned by the light scattering software is assumed to dispense with any reliance on theory to predict retention, and any departure of theoretical predictions from experimental observations is therefore considered of no importance. Separation depends on efficiency as well as selectivity, however, and efficiency can be a strong function of retention. The fractionation of a polydisperse sample by field-flow fractionation never provides a perfectly separated series of monodisperse fractions at the channel outlet. The outlet stream has some residual polydispersity, and it will be shown in this manuscript that the residual polydispersity is inversely related to the fractionating power. Due to the strong dependence of light scattering intensity and its angular distribution on the size of the scattering species, the outlet polydispersity must be minimized if reliable size data are to be obtained from the light scattering detector signal. It is shown that light scattering detection should be used with careful control of fractionating power to obtain optimized analysis of polydisperse samples. Part I is concerned with isocratic operation of As-FlFFF, and part II with programmed operation. Graphical abstract The dash-dotted blue curve describes an assumed log-normal sample molecular weight distribution (right axis

  2. Optimization and evaluation of asymmetric flow field-flow fractionation of silver nanoparticles

    DEFF Research Database (Denmark)

    Löschner, Katrin; Navratilova, Jana; Legros, Samuel;

    2013-01-01

    flow rate and spacer height were shown to have a significant influence on the recoveries and retention times of the nanoparticles. Focus time and focus flow rate were optimized with regard to minimum elution of AgNPs in the void volume. The developed method was successfully tested for injected masses......) and calculations of size based on AF(4) theory. Fraction collection followed by transmission electron microscopy was performed to confirm the obtained size distributions and to obtain further information regarding the AgNP shape. Characteristics of the absorbance spectra were used to confirm the presence of non...

  3. Development and evaluation of methods for starch dissolution using asymmetrical flow field-flow fractionation. Part I: Dissolution of amylopectin.

    Science.gov (United States)

    Perez-Rea, Daysi; Bergenståhl, Björn; Nilsson, Lars

    2015-06-01

    We have investigated methods of starch dissolution with the aim of finding an optimum method to completely dissolve starch granules to form a molecularly dissolved starch solution without degradation of the polymers. Glycogen was used as a model molecule for amylopectin, to identify the dissolution conditions under which the degradation of the polymers was limited or not present. Dissolution was performed in water with temperatures up to 200 °C, facilitated by the use of heating in an autoclave or a microwave oven, or in dimethyl sulfoxide (DMSO) at 100 °C. Waxy maize starch was chosen due to its high content of amylopectin and very low content of amylose. The degree of starch dissolution under different conditions was determined enzymatically. The effect of different dissolution conditions on the molar mass and root-mean-square radius of the polymers was determined with asymmetrical flow field-flow fractionation coupled to multi-angle light scattering and differential refractive index (AF4-MALS-dRI) detectors under aqueous conditions. The results suggest that reliable and accurate size separation and characterization of amylopectin can be obtained by dissolution of starch granules in an aqueous environment at 140 °C by autoclaving or in DMSO at 100 °C. The results also clearly show an upper limit for heat treatment of starch, above which degradation cannot be avoided. PMID:25925852

  4. Study on aggregation behavior of Cytochrome C-conjugated silver nanoparticles using asymmetrical flow field-flow fractionation.

    Science.gov (United States)

    Kim, Sun Tae; Lee, Yong-Ju; Hwang, Yu-Sik; Lee, Seungho

    2015-01-01

    In this study, 40 nm silver nanoparticles (AgNPs) were synthesized using the citrate reduction method and then the surface of AgNPs was modified by conjugating Cytochrome C (Cyto C) to improve stability and to enhance bioactivity and biocompatibility of AgNPs. It is known that Cyto C may undergo conformational changes under various conditions of pH, temperature, ionic strength, etc., resulting in aggregation of the particles. These parameters also affect the size and size distribution of Cyto C-conjugated AgNPs (Cyto C-AgNP). ζ-potential measurement revealed that the adsorption of Cyto C on the surface of AgNPs is saturated at the molar ratio [Cyto C]/[AgNPs] above about 300. Asymmetrical flow field-flow fractionation (AsFlFFF) analysis showed that hydrodynamic diameter of AgNPs increases by about 4 nm when the particle is saturated by Cyto C. The aggregation behavior of Cyto C-AgNP at various conditions of pH, temperature and ionic strength were investigated using AsFlFFF and UV-vis spectroscopy. It was found that the aggregation of Cyto C-AgNP increases with decreasing pH, increasing temperature and ionic strength due to denaturation of Cyto C on AgNPs and reduction in the thickness of electrostatic double layer on the surface of Cyto C-AgNP. PMID:25476400

  5. Aggregation behavior of fullerenes in aqueous solutions: a capillary electrophoresis and asymmetric flow field-flow fractionation study.

    Science.gov (United States)

    Astefanei, Alina; Núñez, Oscar; Galceran, Maria Teresa; Kok, Wim Th; Schoenmakers, Peter J

    2015-10-01

    In this work, the electrophoretic behavior of hydrophobic fullerenes [buckminsterfullerene (C60), C70, and N-methyl-fulleropyrrolidine (C60-pyrr)] and water-soluble fullerenes [fullerol (C60(OH)24); polyhydroxy small gap fullerene, hydrated (C120(OH)30); C60 pyrrolidine tris acid (C60-pyrr tris acid); and (1,2-methanofullerene C60)-61-carboxylic acid (C60CHCOOH)] in micellar electrokinetic capillary chromatography (MECC) was evaluated. The aggregation behavior of the water-soluble compounds in MECC at different buffer and sodium dodecyl sulfate (SDS) concentrations and pH values of the background electrolyte (BGE) was studied by monitoring the changes observed in the electrophoretic pattern of the peaks. Broad and distorted peaks that can be attributed to fullerene aggregation were obtained in MECC which became narrower and more symmetric by working at low buffer and SDS concentrations (below the critical micelle concentration, capillary zone electrophoresis (CZE) conditions). For the characterization of the suspected aggregates formed (size and shape), asymmetrical flow field-flow fractionation (AF4) and transmission electron microscopy (TEM) were used. The results showed that the increase in the buffer concentration promoted the aggregation of the particles, while the presence of SDS micelles revealed multiple peaks corresponding to particles of different aggregation degrees. Furthermore, MECC has been applied for the first time for the analysis of C60 in two different cosmetic products (i.e., anti-aging serum and facial mask). PMID:26314484

  6. Development and evaluation of methods for starch dissolution using asymmetrical flow field-flow fractionation. Part II: Dissolution of amylose.

    Science.gov (United States)

    Perez-Rea, Daysi; Bergenståhl, Björn; Nilsson, Lars

    2016-02-01

    In this paper, we investigate whether dissolution in water under autoclaving conditions (140 °C, 20 min) or in dimethyl sulfoxide, DMSO (100 °C, 1 h), is preferable for characterization of amylose. Two types of amylose, potato and maize, were dissolved either in water using an autoclave or in DMSO. On the aqueous solutions obtained, the extent of molecular dissolution of the sample (referred to as the dissolution yield) was determined by enzymatic analysis as well as the molecular properties, such as molar mass and root-mean-square radius, obtained with asymmetrical flow field-flow fractionation coupled to multi-angle light scattering and differential refractive index detection (AF4-MALS-dRI). The results showed that both dissolution methods are efficient at dissolving amylose. However, AF4-MALS-dRI analysis revealed substantial differences. Amylose aqueous solutions obtained by dissolution in DMSO were relatively stable over time, but the dissolution method in autoclave caused some degradation of the molecules, and their solutions display a high tendency to retrograde. PMID:26232931

  7. Characterization of sodium hyaluronate blends using frit inlet asymmetrical flow field-flow fractionation and multiangle light scattering.

    Science.gov (United States)

    Ali, Muhammad; Hwang, Euijin; Cho, Il-Hwan; Moon, Myeong Hee

    2012-01-01

    We characterized ultrahigh molecular weight sodium hyaluronate (NaHA) and blended pharmaceutical products containing NaHA using flow field-flow fractionation and multiangle light scattering-differential refractive index (FlFFF-MALS-DRI). NaHA is a water-soluble polysaccharide with a range of molecular weights (MW; 10(5)~10(8) Da) that is found in body fluids and tissues. NaHA is also used commercially in pharmaceutical and cosmetic applications. We used a frit inlet asymmetrical FlFFF channel to separate aqueous polymers according to their hydrodynamic size, and we used on-line measurements of light scattering to obtain the MW distribution (MWD) as well as structural information about NaHA in aqueous solution. In this study, we investigated NaHA and anti-adhesive blend mixtures of NaHA (a commercial NaHA blend mixture containing sodium carboxymethyl cellulose and a new blend with hydroxyethyl starch (HES)) to determine the molecular weight distribution MWD of NaHA and the blend mixtures and to obtain structural information about these compounds in aqueous solution. We also examined the characteristics of NaHA-HES-polylactic-co-glycolic acid film products exposed to gamma radiation for sterilization purposes. PMID:22101460

  8. Field-Flow Fractionation.

    Science.gov (United States)

    Caldwell, Karin D.

    1988-01-01

    Describes a technique for separating samples that range over 15 orders of magnitude in molecular weight. Discusses theory, apparatus, and sample preparation techniques. Lists several types of field-flow fractionation (FFF) and their uses: sedimentation FFF, thermal FFF, flow FFF, electrical FFF, and steric FFF. (ML)

  9. Characterization of Silver Nanoparticles under Environmentally Relevant Conditions Using Asymmetrical Flow Field-Flow Fractionation (AF4).

    Science.gov (United States)

    Jang, Min-Hee; Lee, Seungho; Hwang, Yu Sik

    2015-01-01

    The development of methods to monitor manufactured nanomaterials in the environment is one of the crucial areas for the assessment of their risk. More specifically, particle size analysis is a key element, because many properties of nanomaterial are size dependent. The sizing of nanomaterials in real environments is challenging due to their heterogeneity and reactivity with other environmental components. In this study, the fractionation and characterization of a mixture of polyvinylpyrrolidone-coated silver nanoparticles (PVP-AgNPs) of three different sizes were investigated using asymmetrical flow field-flow fractionation (AF4) coupled with UV-Vis spectrophotometry. In particular, the effects of electrolyte composition and natural organic matter (NOM) on the particle size and stability were evaluated. The fractogram peaks (i.e., stability) of three different AgNPs decreased in the presence of both 10 mM NaCl and 10 mM CaCl2, while increased with increasing concentration of humic acid (HA). In addition, the hydrodynamic diameters of AgNPs in both electrolytes slightly increased with an increase of HA concentration, suggesting the adsorption (coating) of HA onto the particle surface. It is also interesting to note that an increase in the particle size depended on the types of electrolyte, which could be explained by the conformational characteristics of the adsorbed HA layers. Consistent these results, AgNPs suspended in lake water containing relatively high concentration of organic carbon (TOC) showed higher particle stability and larger particle size (i.e., by approximately 4 nm) than those in river water. In conclusion, the application of AF4 coupled with highly sensitive detectors could be a powerful method to characterize nanoparticles in natural waters. PMID:26575993

  10. Characterization of aggregates of surface modified fullerenes by asymmetrical flow field-flow fractionation with multi-angle light scattering detection

    OpenAIRE

    Astefanei, Alina; Kok, Wim Th.; Bäuerlein, Patrick; Núñez Burcio, Oscar; Galcerán Huguet, M. Teresa; de Voogt, Pim; Schoenmakers, P.J.

    2015-01-01

    Fullerenes are carbon nanoparticles with widespread biomedical, commercial and industrial applications. Attributes such as their tendency to aggregate and aggregate size and shape impact their ability to be transported into and through the environment and living tissues. Knowledge of these properties is therefore valuable for their human and environmental risk assessment as well as to control their synthesis and manufacture. In this work, asymmetrical flow-field flow fractionation (AF4) coupl...

  11. Fractionation and Characterization of High Aspect Ratio Gold Nanorods Using Asymmetric-Flow Field Flow Fractionation and Single Particle Inductively Coupled Plasma Mass Spectrometry

    OpenAIRE

    Thao M. Nguyen; Jingyu Liu; Hackley, Vincent A.

    2015-01-01

    Gold nanorods (GNRs) are of particular interest for biomedical applications due to their unique size-dependent longitudinal surface plasmon resonance band in the visible to near-infrared. Purified GNRs are essential for the advancement of technologies based on these materials. Used in concert, asymmetric-flow field flow fractionation (A4F) and single particle inductively coupled mass spectrometry (spICP-MS) provide unique advantages for fractionating and analyzing the typically complex mixtur...

  12. Translational diffusion coefficients and hydrodynamic radii of normal corn starch in aqueous media from asymmetrical flow field-flow fractionation experiments

    OpenAIRE

    Juna, Shazia; Huber, Anton

    2015-01-01

    Starch is a highly disperse material with broad distributions of molecular sizes and geometries. Its dissolution in aqueous media is difficult to achieve and it tends to form aggregates through both inter- and intra-molecular interactions. Asymmetrical flow field-flow fractionation (AF4) is a suitable technique for the separation of such macromolecular and colloidal systems. A major advantage of AF4 is the direct correlation of translational diffusion coefficients with retention time and expe...

  13. Characterizing changes in levan physicochemical properties in different pH environments using asymmetric flow field-flow fractionation.

    Science.gov (United States)

    Runyon, J Ray; Nilsson, Lars; Ulmius, Matilda; Castro, Alejandra; Ionescu, Ruxandra; Andersson, Claes; Schmidt, Christoph

    2014-02-01

    The purpose of this study was to assess the stability of the polyfructan levan under different pH solution conditions by monitoring changes in the levan physicochemical properties, such as molar mass (M), root mean square radius (r(rms)), hydrodynamic radius (r(h)), structure factor (r(rms)/r(h)), and aggregation state with respect to solution pH and hydrolysis time. A commercial levan produced from Z. Mobilis was characterized using asymmetric flow field-flow fractionation (AF4) in combination with online multiangle light scattering (MALS) and differential refractive index (dRI) detection. Under neutral pH solution conditions the levan was found to have a M ranging from 10(5) to 5 × 10(7) g/mol, a r(rms) ranging from ~25 to 100 nm and a r(h) from ~3 to 151 nm. Two populations were observed in the sample. One population with a M less than 106 g/mol which represented ~60 % of the sample and a second population with an ultrahigh M up to 5 × 10(7) g/mol, which comprised ~40 % of the sample. The measured r(rms)/r(h) structure factor decreased from 1.8 to 0.65 across the AF4 fractogram indicating that early eluting low M levan species had a random coil configuration and late eluting high M species had more homogeneous spherical structures. The measured apparent density values decreased from 80 to 10 kg/m(3) across the elution profile and suggest that the observed second population also contains aggregates. The stability of levan in different pH conditions ranging from 1.3 to 8.5 was assessed by tracking changes in the average M and r(h), and monitoring the formation of fructose over 1 week. The onset of levan acid hydrolysis was observed to occur sooner at lower pH conditions and no hydrolysis was observed for pH 5.5 and higher. PMID:24121433

  14. Analyzing the influence of PEG molecular weight on the separation of PEGylated gold nanoparticles by asymmetric-flow field-flow fractionation.

    Science.gov (United States)

    Hansen, Matthew; Smith, Mackensie C; Crist, Rachael M; Clogston, Jeffrey D; McNeil, Scott E

    2015-11-01

    Polyethylene glycol (PEG) is an important tool for increasing the biocompatibility of nanoparticle therapeutics. Understanding how these potential nanomedicines will react after they have been introduced into the bloodstream is a critical component of the preclinical evaluation process. Hence, it is paramount that better methods for separating, characterizing, and analyzing these complex and polydisperse formulations are developed. We present a method for separating nominal 30-nm gold nanoparticles coated with various molecular weight PEG moieties that uses only phosphate-buffered saline as the mobile phase, without the need for stabilizing surfactants. The optimized asymmetric-flow field-flow fractionation technique using in-line multiangle light scattering, dynamic light scattering, refractive index, and UV-vis detectors allowed successful separation and detection of a mixture of nanoparticles coated with 2-, 5-, 10-, and 20-kDa PEG. The particles coated with the larger PEG species (10 and 20 kDa) were eluted at times significantly earlier than predicted by field-flow fractionation theory. This was attributed to a lower-density PEG shell for the higher molecular weight PEGylated nanoparticles, which allows a more fluid PEG surface that can be greater influenced by external forces. Hence, the apparent particle hydrodynamic size may fluctuate significantly depending on the overall density of the stabilizing surface coating when an external force is applied. This has considerable implications for PEGylated nanoparticles intended for in vivo application, as nanoparticle size is important for determining circulation times, accumulation sites, and routes of excretion, and highlights the importance and value of the use of secondary size detectors when one is working with complex samples in asymmetric-flow field-flow fractionation. PMID:26449845

  15. The use of asymmetrical flow field-flow fractionation with on-line detection in the study of drug retention within liposomal nanocarriers and drug transfer kinetics

    DEFF Research Database (Denmark)

    Hinna, Askell Hvid; Hupfeld, Stefan; Kuntsche, Judith;

    2016-01-01

    liposomes, the latter serving as a model mimicking biological sinks in the body. The donor- and acceptor-liposomes were subsequently separated using asymmetrical flow field-flow fractionation (AF4), during which the sample is exposed to a large volume of eluent which corresponds to a dilution factor of...... approximately 600. The model drug content in the donor- and acceptor fraction was quantified by on-line UV/VIS extinction measurements with correction for turbidity and by off-line HPLC measurements of collected fractions. The refined method allowed for (near) baseline separation of donor and acceptor vesicles...... both drug transfer and drug release to the aqueous phase. By sampling at specific incubation times, the release and transfer kinetics of the model compound p-THPP (5,10,15,20-tetrakis(4-hydroxyphenyl)21H,23H-porphine) was determined. p-THPP is structurally closely related to the photosensitizer...

  16. Asymmetric Flow Field Flow Fractionation of Aqueous C60 Nanoparticles with Size Determination by Dynamic Light Scattering and Quantification by Liquid Chromatography Atmospheric Pressure Photo-Ionization Mass Spectrometry

    Science.gov (United States)

    A size separation method was developed for aqueous C60 fullerene aggregates (aqu/C60) using asymmetric flow field flow fractionation (AF4) coupled to a dynamic light scattering detector in flow through mode. Surfactants, which are commonly used in AF4, were avoided as they may al...

  17. Study on aggregation behavior of low density lipoprotein in hen egg yolk plasma by asymmetrical flow field-flow fractionation coupled with multiple detectors.

    Science.gov (United States)

    Dou, Haiyang; Magnusson, Emma; Choi, Jaeyeong; Duan, Fei; Nilsson, Lars; Lee, Seungho

    2016-02-01

    In this study, asymmetrical flow field-flow fractionation (AF4) coupled online with UV, multiangle light scattering (MALS), and fluorescence (FS) detectors (AF4-UV-MALS-FS) was employed for separation and characterization of egg yolk plasma. AF4 provided separation of three major components of the egg yolk plasma i.e. soluble proteins, low density lipoproteins (LDL) and their aggregates, based on their respective hydrodynamic sizes. Identification of LDL was confirmed by staining the sample with a fluorescent dye, Nile Red. The effect of carrier liquids on aggregation of LDL was investigated. Collected fractions of soluble proteins were characterized using sodium dodecylsulfate polyacrylamide gel electrophoresis (SDS-PAGE). Moreover, the effect of heat and enzymatic treatment on egg yolk plasma was investigated. The results suggest that enzymatic treatment with phospholipase A2 (PLA2) significantly enhances the heat stability of LDL. The results show that AF4-UV-MALS-FS is a powerful tool for the fractionation and characterization of egg yolk plasma components. PMID:26304341

  18. Multivariate DoE Optimization of Asymmetric Flow Field Flow Fractionation Coupled to Quantitative LC-MS/MS for Analysis of Lipoprotein Subclasses

    Directory of Open Access Journals (Sweden)

    Zsuzsanna Kuklenyik

    2015-02-01

    Full Text Available In this report we demonstrate a practical multivariate design of experiment (DoE approach for asymmetric flow field-flow fractionation (AF4 method optimization using separation of lipoprotein subclasses as an example. First, with the aid of commercially available software, we built a full factorial screening design where the theoretical outcomes were calculated by applying established formulas that govern AF4 channel performance for a 5–35 nm particle size range of interest for lipid particles. Second, using the desirable ranges of instrumental parameters established from theoretical optimization, we performed fractional factorial DoE for AF4 separation of pure albumin and ferritin with UV detection to narrow the range of instrumental parameters and allow optimum size resolution while minimizing losses from membrane immobilization. Third, the optimal range of conditions were tested using response surface DoE for sub-fractionation of high and low density lipoproteins (HDL and LDL in human serum, where the recovery of the analytes were monitored by fraction collection and isotope-dilution LC-MS/MS analysis of each individual fraction for cholesterol and apolipoproteins (ApoA-1 and ApoB-100. Our results show that DoE is an effective tool in combining AF4 theoretical knowledge and experimental data in finding the most optimal set of AF4 instrumental parameters for quantitative coupling with LC-MS/MS measurements.

  19. Fractionation and Characterization of High Aspect Ratio Gold Nanorods Using Asymmetric-Flow Field Flow Fractionation and Single Particle Inductively Coupled Plasma Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Thao M. Nguyen

    2015-07-01

    Full Text Available Gold nanorods (GNRs are of particular interest for biomedical applications due to their unique size-dependent longitudinal surface plasmon resonance band in the visible to near-infrared. Purified GNRs are essential for the advancement of technologies based on these materials. Used in concert, asymmetric-flow field flow fractionation (A4F and single particle inductively coupled mass spectrometry (spICP-MS provide unique advantages for fractionating and analyzing the typically complex mixtures produced by common synthetic procedures. A4F fractions collected at specific elution times were analyzed off-line by spICP-MS. The individual particle masses were obtained by conversion of the ICP-MS pulse intensity for each detected particle event, using a defined calibration procedure. Size distributions were then derived by transforming particle mass to length assuming a fixed diameter. The resulting particle lengths correlated closely with ex situ transmission electron microscopy. In contrast to our previously reported observations on the fractionation of low-aspect ratio (AR GNRs (AR < 4, under optimal A4F separation conditions the results for high-AR GNRs of fixed diameter (≈20 nm suggest normal, rather than steric, mode elution (i.e., shorter rods with lower AR generally elute first. The relatively narrow populations in late eluting fractions suggest the method can be used to collect and analyze specific length fractions; it is feasible that A4F could be appropriately modified for industrial scale purification of GNRs.

  20. Detection and Quantification of Silver Nanoparticles at Environmentally Relevant Concentrations Using Asymmetric Flow Field-Flow Fractionation Online with Single Particle Inductively Coupled Plasma Mass Spectrometry.

    Science.gov (United States)

    Huynh, Khanh An; Siska, Emily; Heithmar, Edward; Tadjiki, Soheyl; Pergantis, Spiros A

    2016-05-01

    The presence of silver nanoparticles (AgNPs) in aquatic environments could potentially cause adverse impacts on ecosystems and human health. However, current understanding of the environmental fate and transport of AgNPs is still limited because their properties in complex environmental samples cannot be accurately determined. In this study, the feasibility of using asymmetric flow field-flow fractionation (AF4) connected online with single particle inductively coupled plasma mass spectrometry (spICPMS) to detect and quantify AgNPs at environmentally relevant concentrations was investigated. The AF4 channel had a thickness of 350 μm and its accumulation wall was a 10 kDa regenerated cellulose membrane. A 0.02% FL-70 surfactant solution was used as an AF4 carrier. With 1.2 mL/min AF4 cross-flow rate, 1.5 mL/min AF4 channel flow rate, and 5 ms spICPMS dwell time, the AF4-spICPMS can detect and quantify 40-80 nm AgNPs, as well as Ag-SiO2 core-shell nanoparticles (51.0 nm diameter Ag core and 21.6 nm SiO2 shell), with good recovery within 30 min. This system was not only effective in differentiating and quantifying different types of AgNPs with similar hydrodynamic diameters, such as in mixtures containing Ag-SiO2 core-shell nanoparticles and 40-80 nm AgNPs, but also suitable for differentiating between 40 nm AgNPs and elevated Ag(+) content. The study results indicate that AF4-spICPMS is capable of detecting and quantifying AgNPs and other engineered metal nanomaterials in environmental samples. Nevertheless, further studies are needed before AF4-spICPMS can become a routine analytical technique. PMID:27104795

  1. Combining asymmetrical flow field-flow fractionation with on- and off-line fluorescence detection to examine biodegradation of riverine dissolved and particulate organic matter.

    Science.gov (United States)

    Lee, Sang Tak; Yang, Boram; Kim, Jin-Yong; Park, Ji-Hyung; Moon, Myeong Hee

    2015-08-28

    This study demonstrated that asymmetrical flow field-flow fractionation (AF4) coupled with on-line UV and fluorescence detection (FLD) and off-line excitation-emission matrix (EEM) fluorescence spectroscopy can be employed to analyze the influence of microbial metabolic activity on the consumption and production of freshwater organic matter. With the AF4 system, organic matter is on-line enriched during a focusing/relaxation period, which is an essential process prior to separation. Size-fractionated chromophoric and fluorophoric organic materials were simultaneously monitored during the 30-min AF4 separation process. Two fractions of different sizes (dissolved organic matter (DOM) and particulate organic matter (POM)) of freshwater samples from three locations (up-, mid-, and downstream) along the Han River basin of Korea were incubated with the same inoculum for 14 days to analyze fraction-specific alterations in optical properties using AF4-UV-FLD. A comparison of AF4 fractograms obtained from pre- and post-incubation samples revealed that POM-derived DOM were more susceptible to microbial metabolic activity than was DOM. Preferential microbial consumption of protein-like DOM components concurred with enhanced peaks of chromophoric and humic-like fluorescent components, presumably formed as by-products of microbial processing. AF4-UV-FLD combined with off-line identification of microbially processed components using EEM fluorescence spectroscopy provides a powerful tool to study the relationship between microbial activity and composition as well as biodegradability of DOM and POM-derived DOM from different origins, especially for the analysis of chromophoric and fluorophoric organic matter that are consumed and produced by microbial metabolic activity. The proposed AF4 system can be applied to organic matter in freshwater samples having low concentration range (0.3-2.5ppm of total organic carbon) without a pre-concentration procedure. PMID:26233252

  2. Feasibility of asymmetrical flow field-flow fractionation as a method for detecting protective antigen by direct recognition of size-increased target-captured nanoprobes.

    Science.gov (United States)

    Shin, Kayeong; Choi, Jaeyeong; Cho, Jun-Haeng; Yoon, Moon-Young; Lee, Seungho; Chung, Hoeil

    2015-11-27

    Asymmetrical flow field-flow fractionation (AF4) was evaluated as a potential analytical method for detection of a protective antigen (PA), an Anthrax biomarker. The scheme was based on the recognition of altered AF4 retention through the generation of the size-increased Au nanoparticle probes as a result of PA binding, in which a PA-selective peptide was conjugated on the probe surface. In the visible absorption-based AF4 fractograms, the band position shifted to a longer retention time as the PA concentration increased due to the presence of probe bound with PAs. The shift was insignificant when the concentration was relatively low at 84.3pM. To improve sensitivity, two separate probes conjugated with two different peptides able to bind on different PA epitopes were used together. The band shift then became distinguishable even at 84.3pM of PA sample. The formation of larger PA-probe inter-connected species using the dual-probe system was responsible for the enhanced band shift. In parallel, the feasibility of surface-enhanced Raman scattering (SERS) as a potential AF4 detection method was also evaluated. In the off-line SERS fractogram constructed using fractions collected during AF4 separation, a band shift was also observed for the 84.3pM PA sample, and the band intensity was higher when using the dual-probe system. The combination of AF4 and SERS is promising for the detection of PA and will become a potential tool if the reproducibility of SERS measurement is improved. PMID:26482872

  3. Characterization of ultrahigh-molecular weight cationic polyacrylamide using frit-inlet asymmetrical flow field-flow fractionation and multi-angle light scattering.

    Science.gov (United States)

    Woo, Sohee; Lee, Ju Yong; Choi, Woonjin; Moon, Myeong Hee

    2016-01-15

    In this study, frit inlet asymmetrical flow field-flow fractionation (FlFFF) with multi-angle light scattering (MALS) and differential refractive index (DRI) detection is utilized for size separation, determination of molecular weight (MW), and conformation of ultrahigh-MW (10(7)-10(9) g/mol) cationic polyacrylamides (C-PAMs), a class of water-soluble copolymers based on acrylamide and vinyl-type comonomers with quaternary ammonium cations that are widely used in wastewater treatment and in paper industries. Linear and branched C-PAM copolymers prepared in two different polymerization methods (solution and emulsion) from varying amounts of crosslinking agent and initiator were size fractionated by FlFFF with field-programming. It was found experimentally that the linear copolymers from both polymerization methods were less than 10(8) g/mol in MW with compact, nearly spherical structures, while the branched C-PAM copolymers from the emulsion polymerization showed a significant increase in average MW up to ∼ 10(9)g/mol, which was about 20-fold greater than those from the solution method, and the branched copolymers had more compact or shrunken conformations. While both linear and branched copolymers less than 10(8) g/mol MW were well resolved in an increasing order of MW (normal mode), it was noted that branched copolymers prepared through emulsion polymerization exhibited significantly larger MWs of 10(8-)10(9) g/mol and eluted in the steric/hyperlayer mode, in which the elution order is reversed in an extreme run condition (strong initial field strength followed by a fast field decay during programming). PMID:26724894

  4. Application of an asymmetric flow field flow fractionation multi-detector approach for metallic engineered nanoparticle characterization - Prospects and limitations demonstrated on Au nanoparticles

    International Nuclear Information System (INIS)

    Highlights: → In this study we present a size- and element selective method, outlined to characterize metallic ENPs, and demonstrated on engineered Au-NP. → A method for quantification of ionic- and particular fraction for nanoparticles in dispersions is presented. → Influence of membrane materials, carrier liquid and flow parameters for A4F was studied. → Comparison of MALLS and DLS for nanoparticle size determination was performed. → Coupling of ICPMS to the A4F, UV/vis and light scattering apparatus is shown. - Abstract: In this work we discuss about the method development, applicability and limitations of an asymmetric flow field flow fractionation (A4F) system in combination with a multi-detector setup consisting of UV/vis, light scattering, and inductively coupled plasma mass spectrometry (ICPMS). The overall aim was to obtain a size dependent-, element specific-, and quantitative method appropriate for the characterization of metallic engineered nanoparticle (ENP) dispersions. Thus, systematic investigations of crucial method parameters were performed by employing well characterized Au nanoparticles (Au-NPs) as a defined model system. For good separation performance, the A4F flow-, membrane-, and carrier conditions were optimized. To obtain reliable size information, the use of laser light scattering based detectors was evaluated, where an online dynamic light scattering (DLS) detector showed good results for the investigated Au-NP up to a size of 80 nm in hydrodynamic diameter. To adapt large sensitivity differences of the various detectors, as well as to guarantee long term stability and minimum contamination of the mass spectrometer a split-flow concept for coupling ICPMS was evaluated. To test for reliable quantification, the ICPMS signal response of ionic Au standards was compared to that of Au-NP. Using proper stabilization with surfactants, no difference for concentrations of 1-50 μg Au L-1 in the size range from 5 to 80 nm for citrate

  5. Characterization of aggregates of surface modified fullerenes by asymmetrical flow field-flow fractionation with multi-angle light scattering detection.

    Science.gov (United States)

    Astefanei, Alina; Kok, Wim Th; Bäuerlein, Patrick; Núñez, Oscar; Galceran, Maria Teresa; de Voogt, Pim; Schoenmakers, Peter J

    2015-08-21

    Fullerenes are carbon nanoparticles with widespread biomedical, commercial and industrial applications. Attributes such as their tendency to aggregate and aggregate size and shape impact their ability to be transported into and through the environment and living tissues. Knowledge of these properties is therefore valuable for their human and environmental risk assessment as well as to control their synthesis and manufacture. In this work, asymmetrical flow-field flow fractionation (AF4) coupled to multi-angle light scattering (MALS) was used for the first time to study the size distribution of surface modified fullerenes with both polyhydroxyl and carboxyl functional groups in aqueous solutions having different pH (6.5-11) and ionic strength values (0-200mM) of environmental relevance. Fractionation key parameters such as flow rates, flow programming, and membrane material were optimized for the selected fullerenes. The aggregation of the compounds studied appeared to be indifferent to changes in solution pH, but was affected by changes in the ionic strength. Polyhydroxy-fullerenes were found to be present mostly as 4nm aggregates in water without added salt, but showed more aggregation at high ionic strength, with an up to 10-fold increase in their mean hydrodynamic radii (200mM), due to a decrease in the electrostatic repulsion between the nanoparticles. Carboxy-fullerenes showed a much stronger aggregation degree in water (50-100nm). Their average size and recoveries decreased with the increase in the salt concentration. This behavior can be due to enhanced adsorption of the large particles to the membrane at high ionic strength, because of their higher hydrophobicity and much larger particle sizes compared to polyhydroxy-fullerenes. The method performance was evaluated by calculating the run-to-run precision of the retention time (hydrodynamic radii), and the obtained RSD values were lower than 1%. MALS measurements showed aggregate sizes that were in good

  6. Differentiation and characterization of isotopically modified silver nanoparticles in aqueous media using asymmetric-flow field flow fractionation coupled to optical detection and mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Gigault, Julien [National Institute of Standards and Technology, Material Measurement Laboratory, 100 Bureau Drive Stop 8520, Gaithersburg, MD 20899-8520 (United States); Hackley, Vincent A., E-mail: vince.hackley@nist.gov [National Institute of Standards and Technology, Material Measurement Laboratory, 100 Bureau Drive Stop 8520, Gaithersburg, MD 20899-8520 (United States)

    2013-02-06

    Highlights: ► Isotopically modified and unmodified AgNPs characterization by A4F-DAD-MALS–DLS-ICP-MS. ► Size-resolved characterization and speciation in simple or complex media. ► Capacity to detect stable isotope enriched AgNPs in a standard estuarine sediment. ► New opportunities to monitor and study fate and transformations of AgNPs. -- Abstract: The principal objective of this work was to develop and demonstrate a new methodology for silver nanoparticle (AgNP) detection and characterization based on asymmetric-flow field flow fractionation (A4F) coupled on-line to multiple detectors and using stable isotopes of Ag. This analytical approach opens the door to address many relevant scientific challenges concerning the transport and fate of nanomaterials in natural systems. We show that A4F must be optimized in order to effectively fractionate AgNPs and larger colloidal Ag particles. With the optimized method one can accurately determine the size, stability and optical properties of AgNPs and their agglomerates under variable conditions. In this investigation, we couple A4F to optical absorbance (UV–vis spectrometer) and scattering detectors (static and dynamic) and to an inductively coupled plasma mass spectrometer. With this combination of detection modes it is possible to determine the mass isotopic signature of AgNPs as a function of their size and optical properties, providing specificity necessary for tracing and differentiating labeled AgNPs from their naturally occurring or anthropogenic analogs. The methodology was then applied to standard estuarine sediment by doping the suspension with a known quantity of isotopically enriched {sup 109}AgNPs stabilized by natural organic matter (standard humic and fulvic acids). The mass signature of the isotopically enriched AgNPs was recorded as a function of the measured particle size. We observed that AgNPs interact with different particulate components of the sediment, and also self-associate to form

  7. Differentiation and characterization of isotopically modified silver nanoparticles in aqueous media using asymmetric-flow field flow fractionation coupled to optical detection and mass spectrometry

    International Nuclear Information System (INIS)

    Highlights: ► Isotopically modified and unmodified AgNPs characterization by A4F-DAD-MALS–DLS-ICP-MS. ► Size-resolved characterization and speciation in simple or complex media. ► Capacity to detect stable isotope enriched AgNPs in a standard estuarine sediment. ► New opportunities to monitor and study fate and transformations of AgNPs. -- Abstract: The principal objective of this work was to develop and demonstrate a new methodology for silver nanoparticle (AgNP) detection and characterization based on asymmetric-flow field flow fractionation (A4F) coupled on-line to multiple detectors and using stable isotopes of Ag. This analytical approach opens the door to address many relevant scientific challenges concerning the transport and fate of nanomaterials in natural systems. We show that A4F must be optimized in order to effectively fractionate AgNPs and larger colloidal Ag particles. With the optimized method one can accurately determine the size, stability and optical properties of AgNPs and their agglomerates under variable conditions. In this investigation, we couple A4F to optical absorbance (UV–vis spectrometer) and scattering detectors (static and dynamic) and to an inductively coupled plasma mass spectrometer. With this combination of detection modes it is possible to determine the mass isotopic signature of AgNPs as a function of their size and optical properties, providing specificity necessary for tracing and differentiating labeled AgNPs from their naturally occurring or anthropogenic analogs. The methodology was then applied to standard estuarine sediment by doping the suspension with a known quantity of isotopically enriched 109AgNPs stabilized by natural organic matter (standard humic and fulvic acids). The mass signature of the isotopically enriched AgNPs was recorded as a function of the measured particle size. We observed that AgNPs interact with different particulate components of the sediment, and also self-associate to form

  8. Feasibility of asymmetric flow field-flow fractionation coupled to ICP-MS for the characterization of wear metal particles and metalloproteins in biofluids from hip replacement patients.

    Science.gov (United States)

    Loeschner, Katrin; Harrington, Chris F; Kearney, Jacque-Lucca; Langton, David J; Larsen, Erik H

    2015-06-01

    Hip replacements are used to improve the quality of life of people with orthopaedic conditions, but the use of metal-on-metal (MoM) arthroplasty has led to poor outcomes for some patients. These problems are related to the generation of micro- to nanosized metal wear particles containing Cr, Co or other elements, but the current analytical methods used to investigate the processes involved do not provide sufficient information to understand the size or composition of the wear particles generated in vivo. In this qualitative feasibility study, asymmetric flow field-flow fractionation (AF(4)) coupled with inductively coupled plasma mass spectrometry (ICP-MS) was used to investigate metal protein binding and the size and composition of wear metal particles present in serum and hip aspirates from MoM hip replacement patients. A well-established HPLC anion exchange chromatography (AEC) separation system coupled to ICP-MS was used to confirm the metal-protein associations in the serum samples. Off-line single particle ICP-MS (spICP-MS) analysis was used to confirm the approximate size distribution indicated by AF(4) of the wear particles in hip aspirates. In the serum samples, AF(4) -ICP-MS suggested that Cr was associated with transferrin (Tf) and Co with albumin (Alb) and an unidentified species; AEC-ICP-MS confirmed these associations and also indicated an association of Cr with Alb. In the hip aspirate sample, AF(4)-ICP-MS suggested that Cr was associated with Alb and Tf and that Co was associated with Alb and two unidentified compounds; AEC analysis confirmed the Cr results and the association of Co with Alb and a second compound. Enzymatic digestion of the hip aspirate sample, followed by separation using AF(4) with detection by UV absorption (280 nm), multi-angle light scattering and ICP-MS, suggested that the sizes of the Cr-, Co- and Mo-containing wear particles in a hip aspirate sample were in the range 40-150 nm. Off-line spICP-MS was used to confirm these

  9. The use of asymmetrical flow field-flow fractionation with on-line detection in the study of drug retention within liposomal nanocarriers and drug transfer kinetics.

    Science.gov (United States)

    Hinna, Askell Hvid; Hupfeld, Stefan; Kuntsche, Judith; Brandl, Martin

    2016-05-30

    Due to their solubilizing capabilities, liposomes (phospholipid vesicles) are suited for designing formulations for intravenous administration of drug compounds which are poorly water-soluble. Despite the good in-vitro stability of such formulations with minimal drug leakage, upon i.v. injection there is a risk of premature drug loss due to drug transfer to plasma proteins and cell membranes. Here we report on the refinement of a recently introduced simple in vitro predictive tool by Hinna and colleagues in 2014, which brings small drug loaded (donor) liposomes in contact with large acceptor liposomes, the latter serving as a model mimicking biological sinks in the body. The donor- and acceptor-liposomes were subsequently separated using asymmetrical flow field-flow fractionation (AF4), during which the sample is exposed to a large volume of eluent which corresponds to a dilution factor of approximately 600. The model drug content in the donor- and acceptor fraction was quantified by on-line UV/VIS extinction measurements with correction for turbidity and by off-line HPLC measurements of collected fractions. The refined method allowed for (near) baseline separation of donor and acceptor vesicles as well as reliable quantification of the drug content not only of the donor- but now also of the acceptor-liposomes due to their improved size-homogeneity, colloidal stability and reduced turbidity. This improvement over the previously reported approach allowed for simultaneous quantification of both drug transfer and drug release to the aqueous phase. By sampling at specific incubation times, the release and transfer kinetics of the model compound p-THPP (5,10,15,20-tetrakis(4-hydroxyphenyl)21H,23H-porphine) was determined. p-THPP is structurally closely related to the photosensitizer temoporfin, which is in clinical use and under evaluation in liposomal formulations. The transfer of p-THPP to the acceptor vesicles followed 1st order kinetics with a half-life of

  10. Accurate Size and Size-Distribution Determination of Polystyrene Latex Nanoparticles in Aqueous Medium Using Dynamic Light Scattering and Asymmetrical Flow Field Flow Fractionation with Multi-Angle Light Scattering

    Directory of Open Access Journals (Sweden)

    Shinichi Kinugasa

    2012-01-01

    Full Text Available Accurate determination of the intensity-average diameter of polystyrene latex (PS-latex by dynamic light scattering (DLS was carried out through extrapolation of both the concentration of PS-latex and the observed scattering angle. Intensity-average diameter and size distribution were reliably determined by asymmetric flow field flow fractionation (AFFFF using multi-angle light scattering (MALS with consideration of band broadening in AFFFF separation. The intensity-average diameter determined by DLS and AFFFF-MALS agreed well within the estimated uncertainties, although the size distribution of PS-latex determined by DLS was less reliable in comparison with that determined by AFFFF-MALS.

  11. In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection

    DEFF Research Database (Denmark)

    Löschner, Katrin; Navratilova, Jana; Grombe, Ringo;

    2015-01-01

    spectrometric detection (AF4-ICP-MS) was applied for quantitative analysis of silver nanoparticles (AgNPs) in a chicken meat matrix following enzymatic sample preparation. For the first time an analytical validation of nanoparticle detection in a food matrix by AF4-ICP-MS has been carried out and the results......Nanomaterials are increasingly used in food production and packaging, and validated methods for detection of nanoparticles (NPs) in foodstuffs need to be developed both for regulatory purposes and product development. Asymmetric flow field-flow fractionation with inductively coupled plasma mass...

  12. Silver and gold nanoparticle separation using asymmetrical flow-field flow fractionation: Influence of run conditions and of particle and membrane charges.

    Science.gov (United States)

    Meisterjahn, Boris; Wagner, Stephan; von der Kammer, Frank; Hennecke, Dieter; Hofmann, Thilo

    2016-04-01

    Flow-Field Flow Fractionation (Flow-FFF), coupled with online detection systems is one of the most promising tools available for the separation and quantification of engineered nanoparticles (ENPs) in complex matrices. To correctly relate the retention of nanoparticles in the Flow-FFF-channel to the particle size, ideal separation conditions must be met. This requires optimization of the parameters that influence the separation behavior. The aim of this study was therefore to systematically investigate and evaluate the influence of parameters such as the carrier liquid, the cross flow, and the membrane material, on the separation behavior of two metallic ENPs. For this purpose the retention, recovery, and separation efficiency of sterically stabilized silver nanoparticles (AgNPs) and electrostatically stabilized gold nanoparticles (AuNPs), which represent two materials widely used in investigations on environmental fate and ecotoxicology, were investigated against a parameter matrix of three different cross-flow densities, four representative carrier solutions, and two membrane materials. The use of a complex mixture of buffers, ionic and non-ionic surfactants (FL-70 solution) together with a medium cross-flow density provided an acceptable compromise in peak quality and recovery for both types of ENPs. However, these separation conditions do not represent a perfect match for both particle types at the same time (maximized recovery at maximized retention). It could be shown that the behavior of particles within Flow-FFF channels cannot be predicted or explained purely in terms of electrostatic interactions. Particles were irreversibly lost under conditions where the measured zeta potentials suggested that there should have been sufficient electrostatic repulsion to ensure stabilization of the particles in the Flow-FFF channel resulting in good recoveries. The wide variations that we observed in ENP behavior under different conditions, together with the different

  13. Influence of protein formulation and carrier solution on asymmetrical flow field-flow fractionation: a case study of the plant-produced recombinant anthrax protective antigen pp-PA83.

    Science.gov (United States)

    Palais, Caroline; Chichester, Jessica A; Manceva, Slobodanka; Yusibov, Vidadi; Arvinte, Tudor

    2015-02-01

    Asymmetrical flow field-flow fractionation (afFFF) was used to investigate the properties of a plant-produced anthrax toxin protective antigen, pp-PA83. The afFFF fractogram consisted of two main peaks with molar masses similar to the molecular mass of pp-PA83 monomer. afFFF carrier solutions strongly influenced the ratio and the intensity of the two main peaks. These differences indicate that conformation changes in the pp-PA83 molecule occurred during the afFFF analysis. Similar fractograms were obtained for different pp-PA83 formulations when the afFFF carrier solution and the protein formulation were the same (or very similar). The data show that in specific cases, afFFF could be used to study protein conformation and document the importance of studying the influence of the carrier solution on afFFF. PMID:25417936

  14. First steps towards a generic sample preparation scheme for inorganic engineered nanoparticles in a complex matrix for detection, characterization, and quantification by asymmetric flow-field flow fractionation coupled to multi-angle light scattering and ICP-MS

    DEFF Research Database (Denmark)

    Wagner, Stephan; Legros, Samuel; Löschner, Katrin;

    2015-01-01

    elemental mass content by asymmetric flow-field flow fractionation coupled to a multi-angle light scattering detector and an inductively coupled plasma mass spectrometer. Following the proposed generic procedure SiO2-ENPs were separated from a tomato soup. Two potential sample preparation methods were...... tested these being acid digestion and colloidal extraction. With the developed method a complete SiO2-ENPs and matrix separation with a Si mass recovery >90% was achieved by acid digestion. The alteration of the particle size distribution was minimized by particle stabilization. The generic procedure...... which also provides quality criteria for method development is urgently needed for standardized and systematic development of procedures for separation of ENPs from a complex matrix. The chosen analytical technique was shown to be suitable for detecting SiO2-ENPs in a complex food matrix like tomato...

  15. Elution modes in field-flow fractionation

    Czech Academy of Sciences Publication Activity Database

    Chmelík, Josef

    New York : Marcel Dekker, 2001, s. 303-306 ISBN 0-8247-0511-4 R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : Field-flow fractionation * elution modes Subject RIV: CB - Analytical Chemistry, Separation

  16. Elemental ratios for characterization of quantum-dots populations in complex mixtures by asymmetrical flow field-flow fractionation on-line coupled to fluorescence and inductively coupled plasma mass spectrometry

    International Nuclear Information System (INIS)

    Highlights: • The hyphenated system allows unequivocal identification of nanoparticle populations. • AF4 separation permitted detection of unexpected nanosized species in a sample. • ICP-QQQ provides elemental ratios with adequate accuracy in every nanoparticle. • Purity and chemical composition of different quantum dot samples were assessed. - Abstract: Separation and identification of nanoparticles of different composition, with similar particle diameter, coexisting in heterogeneous suspensions of polymer-coated CdSe/ZnS quantum dots (QDs) have been thoroughly assessed by asymmetric flow field-flow fractionation (AF4) coupled on-line to fluorescence and inductively coupled plasma mass spectrometry (ICPMS) detectors. Chemical characterization of any previously on-line separated nanosized species was achieved by the measurement of the elemental molar ratios of every element involved in the synthesis of the QDs, using inorganic standards and external calibration by flow injection analysis (FIA). Such elemental molar ratios, strongly limited so far to pure single nanoparticles suspensions, have been achieved with adequate accuracy by coupling for the first time an ICP-QQQ instrument to an AF4 system. This hyphenation turned out to be instrumental to assess the chemical composition of the different populations of nanoparticles coexisting in the relatively complex mixtures, due to its capabilities to detect the hardly detectable elements involved in the synthesis. Interestingly such information, complementary to that obtained by fluorescence, was very valuable to detect and identify unexpected nanosized species, present at significant level, produced during QDs synthesis and hardly detectable by standard approaches

  17. Elemental ratios for characterization of quantum-dots populations in complex mixtures by asymmetrical flow field-flow fractionation on-line coupled to fluorescence and inductively coupled plasma mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Menendez-Miranda, Mario; Fernandez-Arguelles, Maria T.; Costa-Fernandez, Jose M., E-mail: jcostafe@uniovi.es; Encinar, Jorge Ruiz; Sanz-Medel, Alfredo, E-mail: asm@uniovi.es

    2014-08-11

    Highlights: • The hyphenated system allows unequivocal identification of nanoparticle populations. • AF4 separation permitted detection of unexpected nanosized species in a sample. • ICP-QQQ provides elemental ratios with adequate accuracy in every nanoparticle. • Purity and chemical composition of different quantum dot samples were assessed. - Abstract: Separation and identification of nanoparticles of different composition, with similar particle diameter, coexisting in heterogeneous suspensions of polymer-coated CdSe/ZnS quantum dots (QDs) have been thoroughly assessed by asymmetric flow field-flow fractionation (AF4) coupled on-line to fluorescence and inductively coupled plasma mass spectrometry (ICPMS) detectors. Chemical characterization of any previously on-line separated nanosized species was achieved by the measurement of the elemental molar ratios of every element involved in the synthesis of the QDs, using inorganic standards and external calibration by flow injection analysis (FIA). Such elemental molar ratios, strongly limited so far to pure single nanoparticles suspensions, have been achieved with adequate accuracy by coupling for the first time an ICP-QQQ instrument to an AF4 system. This hyphenation turned out to be instrumental to assess the chemical composition of the different populations of nanoparticles coexisting in the relatively complex mixtures, due to its capabilities to detect the hardly detectable elements involved in the synthesis. Interestingly such information, complementary to that obtained by fluorescence, was very valuable to detect and identify unexpected nanosized species, present at significant level, produced during QDs synthesis and hardly detectable by standard approaches.

  18. Asymmetric Flow-Field Flow Fractionation Hyphenated ICP-MS as an Alternative to Cloud Point Extraction for Quantification of Silver Nanoparticles and Silver Speciation: Application for Nanoparticles with a Protein Corona.

    Science.gov (United States)

    Mudalige, Thilak K; Qu, Haiou; Linder, Sean W

    2015-07-21

    Production and application of nanoparticles in consumer products is at an all-time high due to the emerging field of nanotechnology. Direct detection and quantification of trace levels of nanoparticles within consumer products is very challenging and problematic. Although multiple methodologies are available for this purpose, each method has its own set of limitations. Herein, we developed an analytical platform consisting of asymmetric flow-field flow fractionation (AF4) coupled with inductively coupled plasma mass spectroscopy (ICP-MS) for the speciation and quantification of silver ions and silver nanoparticles at the ng/kg level (ppt). AF4 is utilized to concentrate the nanoparticles, and ICP-MS acts as the detector. The protein corona that forms upon exposure of nanoparticles to bovine serum albumin was utilized as a nanoparticle stabilization and AF4 recovery enhancement mechanism. Speciation of silver ions and nanoparticles was achieved with the assistance of penicillamine as a complexation ligand. The effect of nanoparticle size, surface coating, and ionization state toward the detection and quantification of the developed methodology was evaluated. The detection limit was found to be 4 ng/kg with the application of a 5 mL sample loop. Further application of this developed methodology on environmentally relevant samples was demonstrated by the analysis of Arkansas River water spiked with silver nanoparticles and nanoparticle spiked into humic acid solution (50 mg/L) at an environmentally relevant level. PMID:26095720

  19. Examining concentrations and molecular weights of thiols in microorganism cultures and in Churchill River (Manitoba) using a fluorescent-labeling method coupled to asymmetrical flow field-flow fractionation.

    Science.gov (United States)

    Mangal, Vaughn; Guéguen, Celine

    2015-06-01

    In this study, molecular weights of thiols from four laboratory cultures (Scenedesmus obliquus, Chlorella vulgaris, Euglena gracilis, and Attheya septentrionalis) and the Churchill River (Manitoba) were assessed using a fluorescent-labeling method such as monobromotrimethylammoniobimane (qBBr) and asymmetrical flow field-flow fractionation (AF4) coupled to a fluorescence detector. Concentrations of thiols in extracellular fractions ranged from 6.39 ± 3.39 to 39.2 ± 7.43 μmol g(-1), and intracellular concentrations ranged from 11.5 ± 4.52 to 41.0 ± 4.1 μmol g(-1). In addition, molecular weights (MW) of intracellular thiol ranged from 493 ± 24 to 946 ± 12 Da whereas extracellular thiol MWs varied from 443 ± 36 to 810 ± 174 Da. The novel method of combining AF4 to an on-line fluorometer and the incorporation of the thiol tag provided information regarding thiol concentration and composition of controlled and natural systems. Furthermore, the proposed methods allow for the simultaneous measurement of thiol and DOM MWs produced by microorganisms. By assessing characteristics of naturally produced thiols and lab-grown thiols, information regarding heavy metal complexation can be determined. PMID:25772566

  20. Field programming in gravitational field-flow fractionation

    Czech Academy of Sciences Publication Activity Database

    Chmelík, Josef; Plocková, Jana

    Amsterdam, 2002, s. A-12. [FFF'02. International Symposium on Field-Flow Fractionation /10./. Amsterdam (NL), 02.07.2002-05.07.2002] R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : gravitational field-flow fractionation * field programming * hydrodynamic lift forces Subject RIV: CB - Analytical Chemistry, Separation

  1. Hyphenation of Field-Flow Fractionation and Magnetic Particle Spectroscopy

    Directory of Open Access Journals (Sweden)

    Norbert Löwa

    2015-11-01

    Full Text Available Magnetic nanoparticles (MNPs exhibit unique magnetic properties making them ideally suited for a variety of biomedical applications. Depending on the desired magnetic effect, MNPs must meet special magnetic requirements which are mainly determined by their structural properties (e.g., size distribution. The hyphenation of chromatographic separation techniques with complementary detectors is capable of providing multidimensional information of submicron particles. Although various methods have already been combined for this approach, so far, no detector for the online magnetic analysis was used. Magnetic particle spectroscopy (MPS has been proven a straightforward technique for specific quantification and characterization of MNPs. It combines high sensitivity with high temporal resolution; both of these are prerequisites for a successful hyphenation with chromatographic separation. We demonstrate the capability of MPS to specifically detect and characterize MNPs under usually applied asymmetric flow field-flow fractionation (A4F conditions (flow rates, MNP concentration, different MNP types. To this end MPS has been successfully integrated into an A4F multidetector platform including dynamic ligth scattering (DLS, multi-angle light scattering (MALS and ultraviolet (UV detection. Our system allows for rapid and comprehensive characterization of typical MNP samples for the systematic investigation of structure-dependent magnetic properties. This has been demonstrated by magnetic analysis of the commercial magnetic resonance imaging (MRI contrast agent Ferucarbotran (FER during hydrodynamic A4F fractionation.

  2. Trends in Polymer and Particle Characterization by Microfluidic Field-Flow Fractionation Methods: Science or Business?

    Czech Academy of Sciences Publication Activity Database

    Janča, Josef; Sobota, Jaroslav

    2014-01-01

    Roč. 19, 16 May (2014), s. 296-308. ISSN 1023-666X R&D Projects: GA MŠk(CZ) LO1212 Institutional support: RVO:68081731 Keywords : Asymmetrical flow FFF * Electrical FFF * Field- flow fractionation * Flow FFF * Microelectrical FFF * Microfluidic channels * Microthermal FFF * Miniaturization and resolution * Polymers and particles separation * Sedimentation FFF * Technical benefits of microchannels * Thermal FFF Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 1.264, year: 2014

  3. On the no-field method for void time determination in flow field-flow fractionation.

    Science.gov (United States)

    Martin, Michel; Hoyos, Mauricio

    2011-07-01

    Elution time measurements of colloidal particles injected in a symmetrical flow field-flow fractionation (flow FFF) system when the inlet and outlet cross-flow connections are closed have been performed. This no-field method has been proposed earlier for void time (and void volume) determination in flow FFF Giddings et al. (1977). The elution times observed were much larger than expected on the basis of the channel geometrical volume and the flow rate. In order to explain these discrepancies, a flow model allowing the carrier liquid to flow through the porous walls toward the reservoirs located behind the porous elements and along these reservoirs was developed. The ratio between the observed elution time and expected one is found to depend only on a parameter which is a function of the effective permeability and thickness of the porous elements and of the channel thickness and length. The permeabilities of the frits used in the system were measured. Their values lead to predicted elution times in reasonable agreement with experimental ones, taking into account likely membrane protrusion inside the channel on system assembly. They comfort the basic feature of the flow model, in the no-field case. The carrier liquid mostly bypasses the channel to flow along the system mainly in the reservoir. It flows through the porous walls toward the reservoirs near channel inlet and again through the porous walls from the reservoirs to the channel near channel outlet before exiting the system. In order to estimate the extent of this bypassing process, it is desirable that the hydrodynamic characteristics of the permeable elements (permeability and thickness) are provided by flow FFF manufacturers. The model applies to symmetrical as well as asymmetrical flow FFF systems. PMID:21256498

  4. Asymmetric reactions in continuous flow

    Directory of Open Access Journals (Sweden)

    Xiao Yin Mak

    2009-04-01

    Full Text Available An overview of asymmetric synthesis in continuous flow and microreactors is presented in this review. Applications of homogeneous and heterogeneous asymmetric catalysis as well as biocatalysis in flow are discussed.

  5. Field-Flow Fractionation of Carbon Nanotubes and Related Materials

    Energy Technology Data Exchange (ETDEWEB)

    John P. Selegue

    2011-11-17

    During the grant period, we carried out FFF studies of carbonaceous soot, single-walled and multi-walled carbon nanotubes, carbon nano-onions and polyoxometallates. FFF alone does not provide enough information to fully characterize samples, so our suite of characterization techniques grew to include light scattering (especially Photon Correlation Spectroscopy), scanning and transmission electron microscopy, thermogravimetric analysis and spectroscopic methods. We developed convenient techniques to deposit and examine minute FFF fractions by electron microscopy. In collaboration with Arthur Cammers (University of Kentucky), we used Flow Field-Flow Fractionation (Fl-FFF) to monitor the solution-phase growth of keplerates, a class of polyoxometallate (POM) nanoparticles. We monitored the evolution of Mo-POM nanostructures over the course of weeks by by using flow field-flow fractionation and corroborated the nanoparticle structures by using transmission electron microscopy (TEM). Total molybdenum in the solution and precipitate phases was monitored by using inductively coupled plasma analyses, and total Mo-POM concentration by following the UV-visible spectra of the solution phase. We observe crystallization-driven formation of (Mo132) keplerate and solution phase-driven evolution of structurally related nanoscopic species (3-60 nm). FFF analyses of other classes of materials were less successful. Attempts to analyze platelets of layered materials, including exfoliated graphite (graphene) and TaS2 and MoS2, were disappointing. We were not able to optimize flow conditions for the layered materials. The metal sulfides react with the aqueous carrier liquid and settle out of suspension quickly because of their high density.

  6. High Speed Size Sorting of Subcellular Organelles by Flow Field-Flow Fractionation.

    Science.gov (United States)

    Yang, Joon Seon; Lee, Ju Yong; Moon, Myeong Hee

    2015-06-16

    Separation/isolation of subcellular species, such as mitochondria, lysosomes, peroxisomes, Golgi apparatus, and others, from cells is important for gaining an understanding of the cellular functions performed by specific organelles. This study introduces a high speed, semipreparative scale, biocompatible size sorting method for the isolation of subcellular organelle species from homogenate mixtures of HEK 293T cells using flow field-flow fractionation (FlFFF). Separation of organelles was achieved using asymmetrical FlFFF (AF4) channel system at the steric/hyperlayer mode in which nuclei, lysosomes, mitochondria, and peroxisomes were separated in a decreasing order of hydrodynamic diameter without complicated preprocessing steps. Fractions in which organelles were not clearly separated were reinjected to AF4 for a finer separation using the normal mode, in which smaller sized species can be well fractionated by an increasing order of diameter. The subcellular species contained in collected AF4 fractions were examined with scanning electron microscopy to evaluate their size and morphology, Western blot analysis using organelle specific markers was used for organelle confirmation, and proteomic analysis was performed with nanoflow liquid chromatography-tandem mass spectrometry (nLC-ESI-MS/MS). Since FlFFF operates with biocompatible buffer solutions, it offers great flexibility in handling subcellular components without relying on a high concentration sucrose solution for centrifugation or affinity- or fluorescence tag-based sorting methods. Consequently, the current study provides an alternative, competitive method for the isolation/purification of subcellular organelle species in their intact states. PMID:26005782

  7. Depolymerization study of sodium hyaluronate by flow field-flow fractionation/multiangle light scattering.

    Science.gov (United States)

    Kwon, Ji Hye; Hwang, Euijin; Cho, Il-Hwan; Moon, Myeong Hee

    2009-09-01

    Thermal depolymerization of ultrahigh-molecular-weight (UHMW) sodium hyaluronate (NaHA) was studied systematically by using frit-inlet asymmetrical flow field-flow fractionation/multiangle light scattering/differential refractive index (FI-AFlFFF/MALS/DRI). FI-AFlFFF was utilized for the size separation of NaHA samples which had been thermally degraded for varied treatment times, followed by light-scattering detection to determine MW and structural information of degraded NaHA products. Analysis of NaHA products showed time-dependent depolymerization of raw molecules into smaller-MW components, as well as unfolding of compact structures of UHMW NaHA. To determine whether the observed decrease in MW of sodium hyaluronate originated from the chain degradation of UHMW molecules or from dissociation of entangled complex particles that may have been formed by intermolecular association, narrow size fractions (1 x 10(7)-6 x 10(7) and >6 x 10(7) MW) of NaHA molecules were collected during FlFFF separation and followed by thermal treatment. Subsequent FI-AFlFFF/MALS analysis of collected fractions after thermal treatment suggested that the ultrahigh-MW region (>10(7) Da) of NaHA is likely to result from supermolecular structures formed by aggregation of large molecules. PMID:19649622

  8. On the flow magnitude and field-flow alignment at Earth's core surface

    DEFF Research Database (Denmark)

    Finlay, Chris; Amit, H.

    We present a method to estimate the typical magnitude of flow close toEarth's core surface based on observational knowledge of the maingeomagnetic field (MF) and its secular variation (SV), together withprior information concerning field-flow alignment gleaned from numericaldynamo models. An expr...

  9. Paper-based flow fractionation system for preconcentration and field-flow fractionation.

    Science.gov (United States)

    Hong, Seokbin; Kwak, Rhokyun; Kim, Wonjung

    2015-11-01

    We present a novel paper-based flow fractionation system for preconcentration and field-flow fractionation. The paper fluidic system consisting of a straight channel connected with expansion regions can generate a fluid flow with a constant flow rate for 10 min without any external pumping devices. The flow bifurcates with a fraction ratio of up to 30 depending on the control parameters of the channel geometry. Utilizing this simple paper-based bifurcation system, we developed a continuous-flow preconcentrator and a field-flow fractionator on a paper platform. Our experimental results show that the continuous-flow preconcentrator can produce a 33-fold enrichment of the ion concentration and that the flow fractionation system successfully separates the charged dyes. Our study suggests simple, cheap ways to construct preconcentration and field-flow fractionation systems for paper-based microfluidic diagnostic devices. This work was supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIP) (NRF-2015R1A2A2A04006181).

  10. Rapid protein separation and diffusion coefficient measurement by frit inlet flow field-flow fractionation.

    OpenAIRE

    Liu, M. K.; Li, P.; Giddings, J. C.

    1993-01-01

    In this study three flow field-flow fractionation (flow FFF) channels are utilized for the separation of proteins and for the simultaneous measurement of their translational diffusion coefficients, D. One channel has a traditional sample inlet, whereas the other two incorporate a frit inlet design that permits more convenient and rapid sample introduction. The dependence of retention time on D, which leads to differential elution and the opportunity to measure D for protein peaks purified by ...

  11. On the flow magnitude and field-flow alignment at Earth's core surface

    Science.gov (United States)

    Finlay, C. C.; Amit, H.

    2012-12-01

    We present a method to estimate the typical magnitude of flow close to Earth's core surface based on observational knowledge of the main geomagnetic field (MF) and its secular variation (SV), together with prior information concerning field-flow alignment gleaned from numerical dynamo models. An expression linking the core surface flow magnitude to spherical harmonic spectra of the MF and SV is derived from the magnetic induction equation. This involves the angle γ between the flow and the horizontal gradient of the radial field. We study γ in a suite of numerical dynamo models and discuss the physical mechanisms that control it. Horizontal flow is observed to approximately follow contours of the radial field close to high-latitude flux bundles, while more efficient induction occurs at lower latitudes where predominantly zonal flows are often perpendicular to contours of the radial field. We show that the amount of field-flow alignment depends primarily on a magnetic modified Rayleigh number Raη = α g0 Δ T D / η Ω , which measures the vigor of convective driving relative to the strength of magnetic dissipation. Synthetic tests of the flow magnitude estimation scheme are encouraging, with results differing from reference values by less than 8%. Application to a high quality geomagnetic field model based on satellite observations (the xCHAOS model in epoch 2004.0) leads to a flow magnitude estimate of 11 - 14 km / yr, in accordance with previous estimates. When applied to the historical geomagnetic field model gufm1 for the interval 1840.0 - 1990.0, the method predicts temporal variations in flow magnitude similar to those found in earlier studies. The calculations rely primarily on knowledge of the MF and SV spectra; by extrapolating these beyond observed scales the influence of small scales on flow magnitude estimates is assessed. Exploring three possible spectral extrapolations we find that the magnitude of the core surface flow, including small scales, is

  12. Quantitative Characterization of Gold Nanoparticles by Field-Flow Fractionation Coupled Online with Light Scattering Detection and Inductively Coupled Plasma Mass Spectrometry

    OpenAIRE

    Schmidt, Bjørn; Löschner, Katrin; Hadrup, Niels; Mortensen, Alicja; Sloth, Jens Jørgen; Bender Koch, Christian; Larsen, Erik Huusfeldt

    2011-01-01

    An analytical platform coupling asymmetric flow field-flow fractionation (AF4) with multiangle light scattering (MALS), dynamic light scattering (DLS), and inductively coupled plasma mass spectrometry (ICPMS) was established and used for separation and quantitative determination of size and mass concentration of nanoparticles (NPs) in aqueous suspension. Mixtures of three polystyrene (PS) NPs between 20 and 100 nm in diameter and mixtures of three gold (Au) NPs between 10 and 60 nm in diamete...

  13. Magnetic field flow phenomena in a falling particle receiver

    Science.gov (United States)

    Armijo, Kenneth M.; Ho, Clifford; Anderson, Ryan; Christian, Joshua; Babiniec, Sean; Ortega, Jesus

    2016-05-01

    Concentrating solar power (CSP) falling particle receivers are being pursued as a desired means for utilizing low-cost, high-absorptance particulate materials that can withstand high concentration ratios (˜1000 suns), operating temperatures above 700 °C, and inherent storage capabilities which can be used to reduce to levelized cost of electricity (LCOE)1. Although previous falling particle receiver designs have proven outlet temperatures above 800 °C, and thermal efficiencies between 80-90%, performance challenges still exist to operate at higher concentration ratios above 1000 suns and greater solar absorptance levels. To increase absorptance, these receivers will require enhanced particle residence time within a concentrated beam of sunlight. Direct absorption solid particle receivers that can enhance this residence time will have the potential to achieve heat-transfer media temperatures2 over 1000 °C. However, depending on particle size and external forces (e.g., external wind and flow due to convective heat losses), optimized particle flow can be severely affected, which can reduce receiver efficiency. To reduce particle flow destabilization and increase particle residence time on the receiver an imposed magnetic field is proposed based on a collimated design for two different methodologies. These include systems with ferromagnetic and charged particle materials. The approaches will be analytically evaluated based on magnetic field strength, geometry, and particle parameters, such as magnetic moment. A model is developed using the computational fluid dynamics (CFD) code ANSYS FLUENT to analyze these approaches for a ˜2 MWth falling particle receiver at Sandia National Laboratories5,6. Here, assessment will be made with respect to ferromagnetic particles such as iron-oxides, as well as charged particles. These materials will be parametrically assessed (e.g., type, size, dipole moment and geometry) over a range of magnetic permeability, μ values. Modeling

  14. On flow magnitude and field-flow alignment at Earth's core surface

    Science.gov (United States)

    Finlay, Christopher C.; Amit, Hagay

    2011-05-01

    We present a method to estimate the typical magnitude of flow close to Earth's core surface based on observational knowledge of the geomagnetic main field (MF) and its secular variation (SV), together with prior information concerning field-flow alignment gleaned from numerical dynamo models. An expression linking the core surface flow magnitude to spherical harmonic spectra of the MF and SV is derived from the magnetic induction equation. This involves the angle γ between the flow and the horizontal gradient of the radial field. We study γ in a suite of numerical dynamo models and discuss the physical mechanisms that control it. Horizontal flow is observed to approximately follow contours of the radial field close to high-latitude flux bundles, while more efficient induction occurs at lower latitudes where predominantly zonal flows are often perpendicular to contours of the radial field. We show that the amount of field-flow alignment depends primarily on a magnetic modified Rayleigh number Raη=αg0ΔTD/ηΩ, which measures the vigour of convective driving relative to the strength of magnetic dissipation. Synthetic tests of the flow magnitude estimation scheme are encouraging, with results differing from true values by less than 8 per cent. Application to a high-quality geomagnetic field model based on satellite observations (the xCHAOS model in epoch 2004.0) leads to a flow magnitude estimate of 11-14 km yr-1, in accordance with previous estimates. When applied to the historical geomagnetic field model gufm1 for the interval 1840.0-1990.0, the method predicts temporal variations in flow magnitude similar to those found in earlier studies. The calculations rely primarily on knowledge of the MF and SV spectra; by extrapolating these beyond observed scales the influence of small scales on flow magnitude estimates is assessed. Exploring three possible spectral extrapolations we find that the magnitude of the core surface flow, including small scales, is likely

  15. Hollow-Fiber Flow Field-Flow Fractionation for Mass Spectrometry: From Proteins to Whole Bacteria

    Science.gov (United States)

    Reschiglian, Pierluigi; Zattoni, Andrea; Rambaldi, Diana Cristina; Roda, Aldo; Hee Moon, Myeong

    Mass spectrometry (MS) provides analyte identification over a wide molar-mass range. However, particularly in the case of complex matrices, this ability is often enhanced by the use of pre-MS separation steps. A separation, prototype technique for the "gentle" fractionation of large/ultralarge analytes, from proteins to whole cells, is here described to reduce complexity and maintain native characteristics of the sample before MS analysis. It is based on flow field-flow fractionation, and it employs a micro-volume fractionation channel made of a ca. 20 cm hollow-fiber membrane of sub-millimeter section. The key advantages of this technique lie in the low volume and low-cost of the channel, which makes it suitable to a disposable usage. Fractionation performance and instrumental simplicity make it an interesting methodology for in-batch or on-line pre-MS treatment of such samples.

  16. Characterization of Diamond Nanoparticles by High-Speed Micro-Thermal Field-Flow Fractionation

    Czech Academy of Sciences Publication Activity Database

    Janča, Josef

    2015-01-01

    Roč. 20, č. 8 (2015), s. 671-680. ISSN 1023-666X R&D Projects: GA MŠk(CZ) LO1212 Institutional support: RVO:68081731 Keywords : diamond nanoparticles * high-speed microfluidic separation * micro-thermal field-flow fractionation, * article size distribution Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.264, year: 2014

  17. Illustrating Some Principles of Separation Science through Gravitational Field-Flow Fractionation

    Science.gov (United States)

    Beckett, Ronald; Sharma, Reshmi; Andric, Goja; Chantiwas, Rattikan; Jakmunee, Jaroon; Grudpan, Kate

    2007-01-01

    Particle separation is an important but often neglected topic in undergraduate curricula. This article discusses how the method of gravitational field-flow fractionation (GrFFF) can be used to illustrate many principles of separation science and some fundamental concepts of physical chemistry. GrFFF separates particles during their elution through…

  18. Trajectory of microscale entities in a microdevice for field-flow fractionation based on dielectrophoresis

    Science.gov (United States)

    Mathew, Bobby; Alazzam, Anas; Khashan, Saud A.; El-Khasawneh, Bashar S.

    2015-06-01

    This article deals with the development of a two-dimensional dynamic model for tracking the path of cells subjected to dielectrophoresis, in a continuous flow microfluidic device, for purposes of field-flow fractionation. The nonuniform electric field exists between the top and bottom surface of the microchannel; the top electrode runs over the entire length of the microchannel while the bottom surface of the same holds multiple finite sized electrodes of opposite polarity. The model consists of two governing equations with each describing the movement of the cell in one of the two dimensions of interest. The equations governing of the cell trajectories as well as that of the electric potential inside the microchannel are solved using finite difference method. The model is subsequently used for parametric study; the parameters considered include cell radii, actuation voltage, microchannel height and volumetric flow rate. The model is particularly useful in the design of microfluidic device employing dielectrophoresis for field flow fractionation.

  19. Conductivity-Dependent Flow Field-Flow Fractionation of Fulvic and Humic Acid Aggregates

    Directory of Open Access Journals (Sweden)

    Martha J. M. Wells

    2015-09-01

    Full Text Available Fulvic (FAs and humic acids (HAs are chemically fascinating. In water, they have a strong propensity to aggregate, but this research reveals that tendency is regulated by ionic strength. In the environment, conductivity extremes occur naturally—freshwater to seawater—warranting consideration at low and high values. The flow field flow fractionation (flow FFF of FAs and HAs is observed to be concentration dependent in low ionic strength solutions whereas the corresponding flow FFF fractograms in high ionic strength solutions are concentration independent. Dynamic light scattering (DLS also reveals insight into the conductivity-dependent behavior of humic substances (HSs. Four particle size ranges for FAs and humic acid aggregates are examined: (1 <10 nm; (2 10 nm–6 µm; (3 6–100 µm; and (4 >100 µm. Representative components of the different size ranges are observed to dynamically coexist in solution. The character of the various aggregates observed—such as random-extended-coiled macromolecules, hydrogels, supramolecular, and micellar—as influenced by electrolytic conductivity, is discussed. The disaggregation/aggregation of HSs is proposed to be a dynamic equilibrium process for which the rate of aggregate formation is controlled by the electrolytic conductivity of the solution.

  20. Hydrodynamic lift force programming in gravitational field-flow fractionation: a tool for fast and efficient separation of particles

    Czech Academy of Sciences Publication Activity Database

    Chmelík, Josef; Plocková, Jana; Matulík, František

    Colorado: Departnment of Chemistry and Geochemistry, Colorado School of Mines, 2001, s. P15. [International Symposium on Field-Flow Fractionation /9./. Colorado (US), 26.06.2001-29.06.2001] R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : hydrodynamic force * field-flow fractionation Subject RIV: CB - Analytical Chemistry, Separation

  1. Characterization of magnetic nanoparticles using programmed quadrupole magnetic field-flow fractionation

    OpenAIRE

    Williams, P. Stephen; Carpino, Francesca; Zborowski, Maciej

    2010-01-01

    Quadrupole magnetic field-flow fractionation is a relatively new technique for the separation and characterization of magnetic nanoparticles. Magnetic nanoparticles are often of composite nature having a magnetic component, which may be a very finely divided material, and a polymeric or other material coating that incorporates this magnetic material and stabilizes the particles in suspension. There may be other components such as antibodies on the surface for specific binding to biological ce...

  2. Separation of platelets from other blood cells in continuous-flow by dielectrophoresis field-flow-fractionation

    OpenAIRE

    Piacentini, Niccolò; Mernier, Guillaume; Tornay, Raphaël; Renaud, Philippe

    2011-01-01

    We present a microfluidic device capable of separating platelets from other blood cells in continuous flow using dielectrophoresis field-flow-fractionation. The use of hydrodynamic focusing in combination with the application of a dielectrophoretic force allows the separation of platelets from red blood cells due to their size difference. The theoretical cell trajectory has been calculated by numerical simulations of the electrical field and flow speed, and is in agreement with the experiment...

  3. Advanced analysis of polymer emulsions: Particle size and particle size distribution by field-flow fractionation and dynamic light scattering.

    Science.gov (United States)

    Makan, Ashwell C; Spallek, Markus J; du Toit, Madeleine; Klein, Thorsten; Pasch, Harald

    2016-04-15

    Field flow fractionation (FFF) is an advanced fractionation technique for the analyses of very sensitive particles. In this study, different FFF techniques were used for the fractionation and analysis of polymer emulsions/latexes. As model systems, a pure acrylic emulsion and emulsions containing titanium dioxide were prepared and analyzed. An acrylic emulsion polymerization was conducted, continuously sampled from the reactor and subsequently analyzed to determine the particle size, radius of gyration in specific, of the latex particles throughout the polymerization reaction. Asymmetrical flow field-flow fractionation (AF4) and sedimentation field-flow fractionation (SdFFF), coupled to a multidetector system, multi-angle laser light scattering (MALLS), ultraviolet (UV) and refractive index (RI), respectively, were used to investigate the evolution of particle sizes and particle size distributions (PSDs) as the polymerization progressed. The obtained particle sizes were compared against batch-mode dynamic light scattering (DLS). Results indicated differences between AF4 and DLS results due to DLS taking hydration layers into account, whereas both AF4 and SdFFF were coupled to MALLS detection, hence not taking the hydration layer into account for size determination. SdFFF has additional separation capabilities with a much higher resolution compared to AF4. The calculated radii values were 5nm larger for SdFFF measurements for each analyzed sample against the corresponding AF4 values. Additionally a low particle size shoulder was observed for SdFFF indicating bimodality in the reactor very early during the polymerization reaction. Furthermore, different emulsions were mixed with inorganic species used as additives in cosmetics and coatings such as TiO2. These complex mixtures of species were analyzed to investigate the retention and particle interaction behavior under different AF4 experimental conditions, such as the mobile phase. The AF4 system was coupled online

  4. Diffusive processes in the cross-field flow of intense plasma beams

    International Nuclear Information System (INIS)

    We consider magnetic field diffusion in the presence of strongly magnetized electrons (ω/sub ce//tau//sub co/ > 1) as a mechanism for the rapid field penetration observed in cross-field flows of high-β plasma beams. The diffusion has been investigated in several cases which are amenable to analytic solution. The flux penetration times are found to be insensitive to the particular configuration. Comparison with two experiments is made. Agreement within the limits of the experiments is found. Both require an anomalous collision rate which is consistent with observed fluctuations in one case but apparently not the other. 17 refs., 1 fig

  5. Colloidal transport of uranium in soil: Size fractionation and characterization by field-flow fractionation-multi-detection

    International Nuclear Information System (INIS)

    The aim of this study was to characterize colloids associated with uranium by using an on-line fractionation/multi-detection technique based on asymmetrical flow field-flow fractionation (As-Fl-FFF) hyphenated with UV detector, multi angle laser light scattering (MALLS) and inductively coupling plasma-mass spectrometry (ICP-MS). Moreover, thanks to the As-Fl-FFF, the different colloidal fractions were collected and characterized by a total organic carbon analyzer (TOC). Thus it is possible to determine the nature (organic or inorganic colloids), molar mass, size (gyration and hydrodynamic radii) and quantitative uranium distribution over the whole colloidal phase. In the case of the site studied, two populations are highlighted. The first population corresponds to humic-like substances with a molar mass of (1500 ± 300) g mol-1 and a hydrodynamic diameter of (2. 0 ± 0. 2) nm. The second one has been identified as a mix of carbonated nano-particles or clays with organic particles (aggregates and/or coating of the inorganic particles) with a size range hydrodynamic diameter between 30 and 450 nm. Each population is implied in the colloidal transport of uranium: maximum 1% of the uranium content in soil leachate is transported by the colloids in the site studied, according to the depth in the soil. Indeed, humic substances are the main responsible of this transport in sub-surface conditions whereas nano-particles drive the phenomenon in depth conditions. (authors)

  6. Asymmetric counterpropagating fronts without flow.

    Science.gov (United States)

    Andrade-Silva, I; Clerc, M G; Odent, V

    2015-06-01

    Out-of-equilibrium systems exhibit domain walls between different states. These walls, depending on the type of connected states, can display rich spatiotemporal dynamics. In this Rapid Communication, we investigate the asymmetrical counterpropagation of fronts in an in-plane-switching cell filled with a nematic liquid crystal. Experimentally, we characterize the different front shapes and propagation speeds. These fronts present dissimilar elastic deformations that are responsible for their asymmetric speeds. Theoretically, using a phenomenological model, we describe the observed dynamics with fair agreement. PMID:26172647

  7. Electrochemical response and separation in cyclic electric field-flow fractionation.

    Science.gov (United States)

    Chen, Zhi; Chauhan, Anuj

    2007-03-01

    Electric field-flow fractionation (EFFF) is a separation technique that couples a lateral electric field with axial Poiseuille flow to separate particles on the basis of size and/or mobility. In unidirectional EFFF, the field rapidly decreases in time due to charging of the double layer. The field strength could be increased by performing EFFF with cyclic electric fields. In cyclic electric field-flow fractionation (CEFFF), a periodic voltage, which can be either sinusoidal or square-wave, is applied in the lateral direction. In this paper, we measure the electrochemical response of CEFFF, i.e., the current-time response for a given time-dependent voltage and then utilize this electrochemical response in a transport model to predict separation. The CEFFF device studied here comprises two gold-coated glass plates separated by a spacer. The transient current profiles are measured for a step change and cyclic square-shaped voltage. The current profile is compared with the equivalent circuit model, and is fitted to a sum of two decaying exponentials. The dependence of the electrochemical response on voltage, frequency, channel thickness, and salt concentration is studied. Next, the electrochemical data are utilized in the convection-diffusion equation to develop a model for separation by CEFFF. The equations are solved by using a combination of analytical and numerical techniques to determine the mean velocity and the dispersion coefficient of molecules, and to determine the effect of various parameters on the separation efficiency of the EFFF device. Also, the model predictions are compared with experimental data available in the literature. PMID:17265539

  8. Microfabrication of multi-layered electrodes for dielectrophoresis-based field flow fractionation

    Science.gov (United States)

    Mathew, Bobby; Alazzam, Anas; Khashan, Saud A.

    2015-06-01

    This article details the process layout required for realizing a three-dimensional arrangement of electrodes in a microfluidic device for field flow fractionation based on dielectrophoresis. The metal electrodes are placed horizontally, in a stair-case arrangement, and pass through the bulk of the fluid. Several standard microfabrication processes are employed, in realizing this microdevice, including multi-layer photolithography, casting and plasma bonding. Thus the process layout is repeatable and reproducible. The feasibility of this process layout is demonstrated using three electrodes arranged in aforementioned manner; nevertheless, this process can be extended to as many electrodes as desired in the horizontal direction. This process layout can will make applications possible that were not possible till date due to the inability in microfabricating three-dimensional horizontal metal electrodes that run through the entire width of the microchannel.

  9. Hydrodynamic chromatography and field flow fractionation in finite aspect ratio channels.

    Science.gov (United States)

    Shendruk, T N; Slater, G W

    2014-04-25

    Hydrodynamic chromatography (HC) and field-flow fractionation (FFF) separation methods are often performed in 3D rectangular channels, though ideal retention theory assumes 2D systems. Devices are commonly designed with large aspect ratios; however, it can be unavoidable or desirable to design rectangular channels with small or even near-unity aspect ratios. To assess the significance of finite-aspect ratio effects and interpret experimental retention results, an ideal, analytical retention theory is needed. We derive a series solution for the ideal retention ratio of HC and FFF rectangular channels. Rather than limiting devices' ability to resolve samples, our theory predicts that retention curves for normal-mode FFF are well approximated by the infinite plate solution and that the performance of HC is actually improved. These findings suggest that FFF devices need not be designed with large aspect ratios and that rectangular HC channels are optimal when the aspect ratio is unity. PMID:24674643

  10. Separation and characterization of nanoparticles in complex food and environmental samples by field-flow fractionation

    DEFF Research Database (Denmark)

    Kammer, Frank von der; Legros, Samuel; Hofmann, Thilo;

    2011-01-01

    sample preparation, field-flow fractionation (FFF) is one of the most promising techniques to achieve relevant characterization.The objective of this review is to present the current status of FFF as an analytical separation technique for the study of NPs in complex food and environmental samples. FFF......The thorough analysis of natural nanoparticles (NPs) and engineered NPs involves the sequence of detection, identification, quantification and, if possible, detailed characterization. In a complex or heterogeneous sample, each step of this sequence is an individual challenge, and, given suitable...... has been applied for separation of various types of NP (e.g., organic macromolecules, and carbonaceous or inorganic NPs) in different types of media (e.g., natural waters, soil extracts or food samples).FFF can be coupled to different types of detectors that offer additional information...

  11. Top-down and bottom-up lipidomic analysis of rabbit lipoproteins under different metabolic conditions using flow field-flow fractionation, nanoflow liquid chromatography and mass spectrometry.

    Science.gov (United States)

    Byeon, Seul Kee; Kim, Jin Yong; Lee, Ju Yong; Chung, Bong Chul; Seo, Hong Seog; Moon, Myeong Hee

    2015-07-31

    This study demonstrated the performances of top-down and bottom-up approaches in lipidomic analysis of lipoproteins from rabbits raised under different metabolic conditions: healthy controls, carrageenan-induced inflammation, dehydration, high cholesterol (HC) diet, and highest cholesterol diet with inflammation (HCI). In the bottom-up approach, the high density lipoproteins (HDL) and the low density lipoproteins (LDL) were size-sorted and collected on a semi-preparative scale using a multiplexed hollow fiber flow field-flow fractionation (MxHF5), followed by nanoflow liquid chromatography-ESI-MS/MS (nLC-ESI-MS/MS) analysis of the lipids extracted from each lipoprotein fraction. In the top-down method, size-fractionated lipoproteins were directly infused to MS for quantitative analysis of targeted lipids using chip-type asymmetrical flow field-flow fractionation-electrospray ionization-tandem mass spectrometry (cAF4-ESI-MS/MS) in selected reaction monitoring (SRM) mode. The comprehensive bottom-up analysis yielded 122 and 104 lipids from HDL and LDL, respectively. Rabbits within the HC and HCI groups had lipid patterns that contrasted most substantially from those of controls, suggesting that HC diet significantly alters the lipid composition of lipoproteins. Among the identified lipids, 20 lipid species that exhibited large differences (>10-fold) were selected as targets for the top-down quantitative analysis in order to compare the results with those from the bottom-up method. Statistical comparison of the results from the two methods revealed that the results were not significantly different for most of the selected species, except for those species with only small differences in concentration between groups. The current study demonstrated that top-down lipid analysis using cAF4-ESI-MS/MS is a powerful high-speed analytical platform for targeted lipidomic analysis that does not require the extraction of lipids from blood samples. PMID:26087967

  12. Cross-field flow of plasma produced by laser resonance photoionization

    International Nuclear Information System (INIS)

    A slow(v≅700m/s) neodymium plasma was produced by laser resonance photoionization in a transverse magnetic field of up to 2240G. The plasma density was in the range of 7.5 x 107 - 1.7 x 109cm-3. The high-density plasma in the low magnetic field flowed straight and was detected by a planar collector set 60mm downstream from the position of plasma production. On the contrary, the low-density plasma did not flow straight across the high magnetic field. The ion numbers detected by the collector decreased and arrival time to the collector delayed. It was found that the ratio of the ions detected by the collector to those produced by laser beams and the arrival times were functions of the plasma relative dielectric constant εr in the wide ranges of plasma density and magnetic field. When εr >1000, the plasma flowed straight across the magnetic field. Therefore it was concluded that the lowest value of εr for the very slow plasma flow in the transverse magnetic field is also consistent with the theoretical prediction εr >(M/m)1/2 =513 for neodymium plasma, where M/m is the mass ratio of the ion to the electron. (author)

  13. Hot and flowing, asymmetric nuclear matter

    International Nuclear Information System (INIS)

    We develop a consistent treatment for hot and flowing asymmetric nuclear matter. Using the mean-field theory, predictions of the σ- ω Walecka model at finite temperature are compared with the corresponding results of the Zimanyi-Moszlowski and the non-linear models. The statistical theory of grand-canonical potentials is incorporated to the formalism. We also describe the behavior, at finite temperature, of the asymmetric and flowing nuclear matter. As an application, we describe bulk properties of neutron and protoneutron stars by considering the Tolman-Oppenheimer-Volkoff equations. (author)

  14. Investigation of uranium-colloid interactions in soil by dual field-flow fractionation/capillary electrophoresis hyphenated with inductively coupled plasma-mass spectrometry

    International Nuclear Information System (INIS)

    This paper deals with the study of uranium-colloid interactions in a carbonated soil. The work is focused on the immediately available fraction obtained after a leaching process, according to a normalized batch method. In order to characterize the different colloidal carriers, Asymmetrical Flow Field-Flow Fractionation (As-FI-FFF) coupled to different detectors (UV, Multi Angle laser Light Scattering (MALLS) and Inductively coupled Plasma-Mass Spectrometry (ICP-MS)) was used. The colloidal carriers are mainly inorganic particles (carbonated particles and clays) mixed with organic substances. Furthermore, dissolved and colloidal uranium species in the leaching solutions were monitored by Capillary Electrophoresis (CE) coupled to ICP-MS, in order to investigate the uranium/colloids interactions. According to the first results, uranium fate in this specific soil is controlled by sorption/desorption phenomena, strongly pH dependent. (authors)

  15. Quantitative Characterization of Gold Nanoparticles by Field-Flow Fractionation Coupled Online with Light Scattering Detection and Inductively Coupled Plasma Mass Spectrometry

    DEFF Research Database (Denmark)

    Schmidt, Bjørn; Löschner, Katrin; Hadrup, Niels;

    2011-01-01

    An analytical platform coupling asymmetric flow field-flow fractionation (AF4) with multiangle light scattering (MALS), dynamic light scattering (DLS), and inductively coupled plasma mass spectrometry (ICPMS) was established and used for separation and quantitative determination of size and mass...... Au and PS NPs were determined online by MALS and DLS, respectively. The three separated Au NPs were quantified by ICPMS and recovered at 50−95% of the injected masses, which ranged between approximately 8−80 ng of each nanoparticle size. Au NPs adhering to the membrane in the separation channel was...... albumin even in alkaline medium, separation of the Au NPs by AF4 was not possible due to association with undissolved remains of the alkali-treated liver tissues as demonstrated by electron microscopy images....

  16. A Movable Asymmetrical Flow Field-Flow Fractionation System for Size Characterization of Nanoparticles

    International Nuclear Information System (INIS)

    The performance test of the established AF4 system was carried out with polystyrene or silver reference nanoparticles. In order to investigate trace amounts of natural nanoparticles using AF4, highly sensitive detection method or pre-concentration of samples are necessary. In the present work, liquid waveguide capillary cells (LWCCs) with longer optical path length than 1 cm are adopted for enhancing sensitivity of absorption measurement. The optimum separation conditions of AF4 coupled with LWCC system and the limit of detection (LOD) of different cells will be discussed. A movable AF4 system was developed and tested for separation and size characterization of polystyrene and silver reference nanoparticles. For the enhancement of sensitivity on absorption measurement, LWCC with longer optical path length than 1 cm was coupled with the developed AF4 system and the optimized condition of AF4-LWCC system was obtained. The developed AF4 system will be combined with laser-induced breakdown detection (LIBD) for analysis of trace nanoparticles in natural water

  17. Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles

    DEFF Research Database (Denmark)

    Dutz, Silvio; Kuntsche, Judith; Eberbeck, Dietmar;

    2012-01-01

    Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this paper we describe the modification of the magnetic properties of magnetic multicore nanoparticles (MCNPs) by size dependent fractionation. T...... size distributed MCNP fluid classified by AF4 show a strong correlation between hydrodynamic diameter and magnetic properties. Thus we state that AF4 is a suitable technology for reproducible size dependent classification of magnetic multicore nanoparticles suspended as ferrofluids....

  18. A Movable Asymmetrical Flow Field-Flow Fractionation System for Size Characterization of Nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sun Tae; Cho, Hye-Ryun; Cha, Wansik; Jung, Euo Chang [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Seungho [Hannam University, Daejeon (Korea, Republic of)

    2015-05-15

    The performance test of the established AF4 system was carried out with polystyrene or silver reference nanoparticles. In order to investigate trace amounts of natural nanoparticles using AF4, highly sensitive detection method or pre-concentration of samples are necessary. In the present work, liquid waveguide capillary cells (LWCCs) with longer optical path length than 1 cm are adopted for enhancing sensitivity of absorption measurement. The optimum separation conditions of AF4 coupled with LWCC system and the limit of detection (LOD) of different cells will be discussed. A movable AF4 system was developed and tested for separation and size characterization of polystyrene and silver reference nanoparticles. For the enhancement of sensitivity on absorption measurement, LWCC with longer optical path length than 1 cm was coupled with the developed AF4 system and the optimized condition of AF4-LWCC system was obtained. The developed AF4 system will be combined with laser-induced breakdown detection (LIBD) for analysis of trace nanoparticles in natural water.

  19. A theory-based approach to thermal field-flow fractionation of polyacrylates.

    Science.gov (United States)

    Runyon, J Ray; Williams, S Kim Ratanathanawongs

    2011-09-28

    A theory-based approach is presented for the development of thermal field-flow fractionation (ThFFF) of polyacrylates. The use of ThFFF for polymer analysis has been limited by an incomplete understanding of the thermal diffusion which plays an important role in retention and separation. Hence, a tedious trial-and-error approach to method development has been the normal practice when analyzing new materials. In this work, thermal diffusion theories based on temperature dependent osmotic pressure gradient and polymer-solvent interaction parameters were used to estimate thermal diffusion coefficients (D(T)) and retention times (t(r)) for different polymer-solvent pairs. These calculations identified methyl ethyl ketone as a solvent that would cause significant retention of poly(n-butyl acrylate) (PBA) and poly(methyl acrylate) (PMA). Experiments confirmed retention of these two polymers that have not been previously analyzed by ThFFF. Theoretical and experimental D(T)s and t(r)s for PBA, PMA, and polystyrene in different solvents agreed to within 20% and demonstrate the feasibility of this theory-based approach. PMID:21872869

  20. On the retention mechanisms and secondary effects in microthermal field-flow fractionation of particles.

    Science.gov (United States)

    Janca, Josef; Stejskal, Jaroslav

    2009-12-25

    The behavior of nanometer or micrometer-sized particles, dispersed in liquid phase and exposed to temperature gradient, is a complex and not yet well understood phenomenon. Thermal field-flow fractionation (TFFF), using conventional-size channels, played an important role in the studies of this phenomenon. In addition to thermal diffusion (thermophoresis) and molecular diffusion or Brownian movement, several secondary effects such as particle-particle and/or particle-wall interactions, chemical equilibria with the components of the carrier liquid, buoyant and lift forces, etc., may contribute to the retention and complicate the understanding of the relations between the thermal diffusion and the characteristics of the retained particles. Microthermal FFF is a new high-performance technique allowing much easier manipulation and control of the operational parameters within an extended range of experimental conditions in comparison with conventional TFFF. Consequently, in combination with various other methods, it is well suited for a detailed investigation of the mentioned effects. In this work, some contradictory published results concerning the thermal diffusion of the colloidal particles, studied by TFFF but also by other methods, are analyzed and compared with our experimental findings. PMID:19552912

  1. Field programming in gravitational field-flow fractionation: a tool for fast and efficient separation of particles

    Czech Academy of Sciences Publication Activity Database

    Plocková, Jana; Matulík, František; Chmelík, Josef

    Bratislava: Polymer Institute of the Slovak Academy of Sciences, 2001, s. 68. [International Bratislava Meeting on Polymers /16./. Bratislava (SK), 09.09.2001-13.09.2001] R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : field flow fractionation * force field programming * separation Subject RIV: CB - Analytical Chemistry, Separation

  2. Characterization of aquatic humic substances by Flow Field-Flow Fractionation (FFFF) and Gel Permeation Chromatography (GPC): A comparison

    International Nuclear Information System (INIS)

    Aquatic humic substances (HS) of different origin are characterized for their molecular size distribution by the flow field-flow fractionation (FFFF) technique. The results are compared with those obtained by classical gel permeation chromatography (GPC). The influence of different parameters such as eluent composition, crossflow, and type of membrane on the fractionation is investigated. Molecular weight at peak maximum and corresponding weight- and number averaged molecular weights are determined using polystyrenesulphonate calibration standards. Results obtained by FFFF and GPC are comparable, even though the recovery of HS with FFFF is higher. In accordance with the literature, fulvic acids are found to be somewhat smaller than humic acids. Investigated HS samples show molecular weights at peak maximum in the range of 2 to 3 kilodalton. (authors)

  3. Improvement of Separation of Polystyrene Particles with PAN Membranes in Hollow Fiber Flow Field-Flow Fractionation

    International Nuclear Information System (INIS)

    Hollow Fiber flow field-flow fractionation (HF-FlFFF) has been tested in polyacrylonitrile (PAN) membrane channel in order to compare it with polysulfone (PSf) membrane channel. It has been experimentally shown that the separation time of 0.05-0.304 μm polystyrene latex (PSL) standards in PAN membrane channel is shorter than that in PSf channel by approximately 65%. The optimized separation condition in PAN membrane is Vout/ Vrad = 1.4/0.12 mL/min, which is equal to the condition in PSf membrane channel. In addition both the resolution (Rs) and plate height (H) in PAN membrane channel are better than that in PSf membrane channel. The membrane radius was obtained by back calculation with retention time. It shows that the PSf membrane is expanded by swelling and pressure, but the PAN membrane doesn't expand by swelling and pressure

  4. Size characterization by Sedimentation Field Flow Fractionation of silica particles used as food additives

    International Nuclear Information System (INIS)

    Graphical abstract: -- Highlights: •Four types of SiO2 particles were characterized by SdFFF, PCS and EM techniques. •Clusters of 10 nm nanoparticles were found in some SiO2 samples. •A method was set up to extract SiO2 particles from food matrices. •The effects of the carrier solution composition on SdFFF separations were evaluated. •Particle size distributions were obtained from SiO2 particles extracted from foodstuffs. -- Abstract: Four types of SiO2, available on the market as additives in food and personal care products, were size characterized using Sedimentation Field Flow Fractionation (SdFFF), SEM, TEM and Photon Correlation Spectroscopy (PCS). The synergic use of the different analytical techniques made it possible, for some samples, to confirm the presence of primary nanoparticles (10 nm) organized in clusters or aggregates of different dimension and, for others, to discover that the available information is incomplete, particularly that regarding the presence of small particles. A protocol to extract the silica particles from a simple food matrix was set up, enriching (0.25%, w w−1) a nearly silica-free instant barley coffee powder with a known SiO2 sample. The SdFFF technique, in conjunction with SEM observations, made it possible to identify the added SiO2 particles and verify the new particle size distribution. The SiO2 content of different powdered foodstuffs was determined by graphite furnace atomic absorption spectroscopy (GFAAS); the concentrations ranged between 0.006 and 0.35% (w w−1). The protocol to isolate the silica particles was so applied to the most SiO2-rich commercial products and the derived suspensions were separated by SdFFF; SEM and TEM observations supported the size analyses while GFAAS determinations on collected fractions permitted element identification

  5. Flow field-flow fractionation and characterization of ionic and neutral polysaccharides of vegetable and microbial origin.

    Science.gov (United States)

    Benincasa, Maria-Anna; Cartoni, Giampaolo; Delle Fratte, Chiara

    2002-08-23

    The flow field-flow fractionation (FlFFF) analysis of a variety of neutral as well as ionic polysaccharides from plants and micro-organisms shows the generally broad distribution in molecular size of these polymers. This result is also obtained on a commercial sample of pullulan whose size distribution appears much wider than that of any of five standard fractions of the same polymer. Clear evidence of some physico-chemical properties of the polysaccharides is given by the study of the effect of the carrier ionic strength on salep, oxidized salep and konjac, carboxymethylcellulose and hyaluronic acid. While neutral polysaccharides, regardless of their origin, only slightly change size distribution in the presence of a simple electrolyte in solution, charged polymers, either naturally charged or chemically ionized, consistently exhibit very low retention levels in water which dramatically increase even at low salt concentrations. Exclusion mechanisms, including steric effects, are shown to be responsible for the anticipated retention times in water of these species that assume the expected statistical coil behavior only when electric charges are screened by the added electrolyte. Under these conditions, higher retention levels are obtained because the volume adjacent to the accumulation wall becomes more accessible to the sample during relaxation. On the basis of these findings, the elution behavior of a number of polysaccharide samples in-laboratory obtained from the fungus Aureobasidium pullulans under different incubation conditions is attributed to the presence of species varying in physico-chemical properties and molecular size. PMID:12685569

  6. Online Coupling of Flow-Field Flow Fractionation and Single Particle Inductively Coupled Plasma-Mass Spectrometry: Characterization of Nanoparticle Surface Coating Thickness and Aggregation State

    Science.gov (United States)

    Surface coating thickness and aggregation state have strong influence on the environmental fate, transport, and toxicity of engineered nanomaterials. In this study, flow-field flow fractionation coupled on-line with single particle inductively coupled plasma-mass spectrometry i...

  7. Different elution modes and field programming in gravitational field-flow fractionation. III. Field programming by flow-rate gradient generated by a programmable pump

    Czech Academy of Sciences Publication Activity Database

    Plocková, Jana; Chmelík, Josef

    2001-01-01

    Roč. 918, č. 2 (2001), s. 361-370. ISSN 0021-9673 R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : field-flow fractionation * field programming * flow-rate gradients Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.793, year: 2001

  8. Micropolarity Ramification of Asymmetric Merging Flow

    CERN Document Server

    Siddiqui, Abuzar Abid

    2016-01-01

    The steady, asymmetric and two-dimensional flow of viscous, incompressible micropolar fluid through a rectangular channel with a splitter (parallel to walls) was formulated and simulated numerically. The plane Poiseuille flow was considered far from upstream and downstream of the splitter. The geometric parameter that controls the position of splitter was defined as splitter position parameter. A numerical scheme that comprises a fourth order method followed by special finite-difference method was used to solve the boundary value problem. This numerical scheme transforms the governing equations to system of finite difference equations which we have solved by SOR iterative method. Moreover, the results obtained were further refined and upgraded by the Richardson extrapolation method. The results were compared on different grid sizes as well as with the existing results for symmetric flow of Newtonian fluids. The comparisons were satisfactory. The microrotation effects on the splitter plate were significantly h...

  9. The steady-state solution of dendritic growth from the undercooled binary alloy melt with the far field flow

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The steady-state dendritic growth from the undercooled binary alloy melt with the far field flow is considered. By neglecting the interface energy, interface kinetics and buoyancy effects in the system, we obtaine the steady-state solution for the case of the large Schmidt number, in terms of the multiple variable expansion method. The changes of the temperature and concentration fields, the morphology of the interface, the normalization parameter and the Peclet number of the system induced by uniform external flow are derived. The results show that, compared with the system of dendritic growth from undercooled pure melt, the convective flow in the system of growth from undercooled binary alloy has stronger effects on the morphology of the interface. Nevertheless, the shape of the interface still remains nearly a paraboloid.

  10. The steady-state solution of dendritic growth from the undercooled binary alloy melt with the far field flow

    Institute of Scientific and Technical Information of China (English)

    CHEN MingWen; WANG ZiDong; XU JianJun

    2009-01-01

    The steady-state dendritic growth from the undercooled binary alloy melt with the far field flow is considered.By neglecting the interface energy,interface kinetics and buoyancy effects in the system,we obtaine the steady-state solution for the case of the large Schmidt number,in terms of the multiple variable expansion method.The changes of thtemperature and concentration fields,the morphology of the interface,the normalization parameter and the Peclet number of the system induced by uniform external flow are derived.The results show that,compared with the system of dendritic growth from undercooled pure melt,the convective flow in the system of growth from undercooled binary alloy has stronger effects on the morphology of the interface.Nevertheless,the shape of the interface still remains nearly a paraboloid.

  11. Survey of near-field flow calculations for nuclear waste repositories NMA L21

    International Nuclear Information System (INIS)

    A survey of methods and codes which describe the flow of groundwater and the migration of radioactive waste in and about nuclear repositories was performed. A number of laboratories engaged in studies of waste migration and groundwater flow were visited in order to discuss the general problem and obtain reports of work being performed. The results of this survey are discussed

  12. Laminar crossed-field flow stability in slow wave cavities: A singularity-free approach

    International Nuclear Information System (INIS)

    A linear stability approach free from the singularities of the cold fluid theory is applied to laminar ExB flows in slow wave cavities. Employing time scale separation in the appropriate frame of reference, one avoids singularities in the guiding center motion near the drift and drift-cyclotron resonances ω-ku0(x)=nΩ, n=0,±1. Instead of an a priori Fourier mode expansion, a boundary value problem is solved with a traveling wave boundary condition at the wall. The space-charge potential is obtained in closed form using the Green's function approach. Due to the incompressibility of the flow, charge perturbations and energy exchange take place at the free flow boundaries (surface perturbations). A local expansion of the Green's function in terms of the perturbation amplitude and its derivative at the boundary yields the self-consistent closure. The loaded cavity mode profiles are everywhere free from singularities, exhibiting local maxima at the flow boundaries, not at the resonant layer(s). The small signal growth is biexponential ∝eΓt2, where Γ scales as the diocotron frequency squared Ω2D=ω4p/Ω2, and is independent of the frequency detuning from resonance. The method is compared to the normal mode analysis and the vacuum mode expansion technique. copyright 1995 American Institute of Physics

  13. On the retention mechanisms and secondary effects in microthermal field-flow fractionation of particles

    Czech Academy of Sciences Publication Activity Database

    Janča, J.; Stejskal, Jaroslav

    2009-01-01

    Roč. 1216, č. 52 (2009), s. 9071-9080. ISSN 0021-9673 Institutional research plan: CEZ:AV0Z40500505 Keywords : hydrodynamic lift forces * slow shear-flow * macroscopic rigid spheres Subject RIV: CD - Macromolecular Chemistry Impact factor: 4.101, year: 2009

  14. Isospin effect on elliptical flow for mass asymmetric nuclear collisions

    International Nuclear Information System (INIS)

    Collective flow is the measure of the transverse motion imparted to the particles and fragments during the collision of two nuclei. Among the different kind of collective flow, elliptical flow enjoys the special status due to its sensitivity towards reaction dynamics. The azimuthal asymmetric emission pattern in which particles found to be preferentially emitted perpendicular to the reaction plane describes the elliptical flow. Elliptical flow has been studied extensively at BEVALAC, SIS and AGS energies. The present work is carried out to study the effect of Coulomb potential on the transverse momentum dependence of elliptical flow by taking mass asymmetric collisions. The study is performed within the frame work of IQMD model

  15. Cross-field flow and electric potential in a plasma slab

    Directory of Open Access Journals (Sweden)

    J. De Keyser

    2013-08-01

    Full Text Available We consider cross-field plasma flow inside a field-aligned plasma slab embedded in a uniform background in a 1-dimensional geometry. This situation may arise, for instance, when long-lasting reconnection pulses inject plasma into the inner magnetosphere. The present paper presents a detailed analysis of the structure of the interfaces that separate the slab from the background plasma on either side; a fully kinetic model is used to do so. Since the velocity shear across both interfaces has opposite signs, and given the typical gyroradius differences between injected and background ions and electrons, the structure of both interfaces can be very different. The behaviour of the slab and its interfaces depends critically on the flow of the plasma transverse to the magnetic field; in particular, it is shown that there are bounds to the flow speed that can be supported by the magnetised plasma. Further complicating the picture is the effect of the potential difference between the slab and its environment.

  16. Quantitative characterization of gold nanoparticles by field-flow fractionation coupled online with light scattering detection and inductively coupled plasma mass spectrometry.

    Science.gov (United States)

    Schmidt, Bjørn; Loeschner, Katrin; Hadrup, Niels; Mortensen, Alicja; Sloth, Jens J; Koch, Christian Bender; Larsen, Erik H

    2011-04-01

    An analytical platform coupling asymmetric flow field-flow fractionation (AF(4)) with multiangle light scattering (MALS), dynamic light scattering (DLS), and inductively coupled plasma mass spectrometry (ICPMS) was established and used for separation and quantitative determination of size and mass concentration of nanoparticles (NPs) in aqueous suspension. Mixtures of three polystyrene (PS) NPs between 20 and 100 nm in diameter and mixtures of three gold (Au) NPs between 10 and 60 nm in diameter were separated by AF(4). The geometric diameters of the separated PS NPs and the hydrodynamic diameters of the Au and PS NPs were determined online by MALS and DLS, respectively. The three separated Au NPs were quantified by ICPMS and recovered at 50-95% of the injected masses, which ranged between approximately 8-80 ng of each nanoparticle size. Au NPs adhering to the membrane in the separation channel was found to be a major cause for incomplete recoveries. The lower limit of detection (LOD) ranged between 0.02 ng Au and 0.4 ng Au, with increasing LOD by increasing nanoparticle diameter. The analytical platform was applied to characterization of Au NPs in livers of rats, which were dosed with 10 nm, 60 nm, or a mixture of 10 and 60 nm nanoparticles by intravenous injection. The homogenized livers were solubilized in tetramethylammonium hydroxide (TMAH), and the recovery of Au NPs from the livers amounted to 86-123% of their total Au content. In spite of successful stabilization with bovine serum albumin even in alkaline medium, separation of the Au NPs by AF(4) was not possible due to association with undissolved remains of the alkali-treated liver tissues as demonstrated by electron microscopy images. PMID:21355549

  17. A novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation

    Directory of Open Access Journals (Sweden)

    Yost Garold S

    2008-12-01

    Full Text Available Abstract A novel methodology to detect unlabeled inorganic nanoparticles was experimentally demonstrated using a mixture of nano-sized (70 nm and submicron (250 nm silicon dioxide particles added to mammalian tissue. The size and concentration of environmentally relevant inorganic particles in a tissue sample can be determined by a procedure consisting of matrix digestion, particle recovery by centrifugation, size separation by sedimentation field-flow fractionation (SdFFF, and detection by light scattering. Background Laboratory nanoparticles that have been labeled by fluorescence, radioactivity, or rare elements have provided important information regarding nanoparticle uptake and translocation, but most nanomaterials that are commercially produced for industrial and consumer applications do not contain a specific label. Methods Both nitric acid digestion and enzyme digestion were tested with liver and lung tissue as well as with cultured cells. Tissue processing with a mixture of protease enzymes is preferred because it is applicable to a wide range of particle compositions. Samples were visualized via fluorescence microscopy and transmission electron microscopy to validate the SdFFF results. We describe in detail the tissue preparation procedures and discuss method sensitivity compared to reported levels of nanoparticles in vivo. Conclusion Tissue digestion and SdFFF complement existing techniques by precisely identifying unlabeled metal oxide nanoparticles and unambiguously distinguishing nanoparticles (diameter

  18. Coupled flows and oscillations in asymmetric rotating plasmas

    International Nuclear Information System (INIS)

    Nonlinear coupling among the radial, axial, and azimuthal flows in an asymmetric cold rotating plasma is considered nonperturbatively. Exact solutions describing an expanding or contracting plasma with oscillations are then obtained. It is shown that despite the flow asymmetry the energy in the radial and axial flow components can be transferred to the azimuthal component but not the vice versa, and that flow oscillations need not be accompanied by density oscillations.

  19. Relationship between the ratio of large and small starch granules determined by gravitational field-flow fractionation and malting quality of barley varieties

    Czech Academy of Sciences Publication Activity Database

    Chmelík, Josef; Mazanec, Karel; Bohačenko, I.; Psota, V.

    2007-01-01

    Roč. 30, 9-10 (2007), s. 1289-1301. ISSN 1082-6076 R&D Projects: GA MZe QD1005 Institutional research plan: CEZ:AV0Z40310501 Keywords : gravitational field-flow fractionation * starch granules * barley varieties Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 0.977, year: 2007

  20. Different elution modes and field programming in gravitational field-flow fractionation IV. Field programming achieved with channels of non-constant cross-sections

    Czech Academy of Sciences Publication Activity Database

    Plocková, Jana; Matulík, František; Chmelík, Josef

    2002-01-01

    Roč. 955, č. 1 (2002), s. 95-103. ISSN 0021-9673 R&D Projects: GA AV ČR IAA4031805 Institutional research plan: CEZ:AV0Z4031919 Keywords : gravitational field-flow fractionation * field programming * hydrodynamic lift forces Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.098, year: 2002

  1. Exact velocity of dispersive flow in the asymmetric avalanche process

    OpenAIRE

    Ivashkevich, E. V.; Povolotsky, A. M.; Priezzhev, V.B.

    2000-01-01

    Using the Bethe ansatz we obtain the exact solution for the one-dimensional asymmetric avalanche process. We evaluate the velocity of dispersive flow as a function of driving force and the density of particles. The obtained solution shows a dynamical transition from intermittent to continuous flow.

  2. Numerical simulation of steady and unsteady asymmetric vortical flow

    Science.gov (United States)

    Kandil, Osama A.; Wong, Tin-Chee; Liu, C. H.

    1992-01-01

    The unsteady, compressible, thin-layer, Navier-Stokes (NS) equations are solved to simulate steady and unsteady, asymmetric, vortical laminar flow around cones at high incidences and supersonic Mach numbers. The equations are solved by using an implicit, upwind, flux-difference splitting (FDS), finite-volume scheme. The locally conical flow assumption is used and the solutions are obtained by forcing the conserved components of the flowfield vector to be equal at two axial stations located at 0.95 and 1.0. Computational examples cover steady and unsteady asymmetric flows around a circular cone and its control using side strakes. The unsteady asymmetric flow solution around the circular cone has also been validated using the upwind, flux-vector splitting (FVS) scheme with the thin-layer NS equations and the upwind FDS with the full NS equations. The results are in excellent agreement with each other. Unsteady asymmetric flows are also presented for elliptic- and diamond-section cones, which model asymmetric vortex shedding around round- and sharp-edged delta winds.

  3. Phoretic flow induced by asymmetric confinement

    CERN Document Server

    Lisicki, Maciej; Lauga, Eric

    2016-01-01

    Internal phoretic flows due to the interactions of solid boundaries with local chemical gradients may be created using chemical patterning. Alternatively, we demonstrate here that internal flows might also be induced by geometric asymmetries of chemically-homogeneous surfaces. We characterise the circulatory flow created in a cavity enclosed between two eccentric cylindrical walls of uniform chemical activity. Local gradients of the diffusing solute induce a slip flow along the surface of the cylinders, leading to a circulatory bulk flow pattern which can be solved analytically in the diffusive limit. The flow strength can be controlled by adjusting the relative positions of the cylinders and an optimal configuration is identified. These results provide a model system for tunable phoretic pumps.

  4. Different elution modes and field programming in gravitational field-flow fractionation. III. Field programming by flow-rate gradient generated by a programmable pump.

    Science.gov (United States)

    Plocková, J; Chmelík, J

    2001-05-25

    Gravitational field-flow fractionation (GFFF) utilizes the Earth's gravitational field as an external force that causes the settlement of particles towards the channel accumulation wall. Hydrodynamic lift forces oppose this action by elevating particles away from the channel accumulation wall. These two counteracting forces enable modulation of the resulting force field acting on particles in GFFF. In this work, force-field programming based on modulating the magnitude of hydrodynamic lift forces was implemented via changes of flow-rate, which was accomplished by a programmable pump. Several flow-rate gradients (step gradients, linear gradients, parabolic, and combined gradients) were tested and evaluated as tools for optimization of the separation of a silica gel particle mixture. The influence of increasing amount of sample injected on the peak resolution under flow-rate gradient conditions was also investigated. This is the first time that flow-rate gradients have been implemented for programming of the resulting force field acting on particles in GFFF. PMID:11407583

  5. Thomson scattering measurements from asymmetric interpenetrating plasma flows

    International Nuclear Information System (INIS)

    Imaging Thomson scattering measurements of collective ion-acoustic fluctuations have been utilized to determine ion temperature and density from laser produced counter-streaming asymmetric flows. Two foils are heated with 8 laser beams each, 500 J per beam, at the Omega Laser facility. Measurements are made 4 mm from the foil surface using a 60 J 2ω probe laser with a 200 ps pulse length. Measuring the electron density and temperature from the electron-plasma fluctuations constrains the fit of the multi-ion species, asymmetric flows theoretical form factor for the ion feature such that the ion temperatures, ion densities, and flow velocities for each plasma flow are determined

  6. Thomson scattering measurements from asymmetric interpenetrating plasma flows

    Energy Technology Data Exchange (ETDEWEB)

    Ross, J. S., E-mail: ross36@llnl.gov; Moody, J. D.; Fiuza, F.; Ryutov, D.; Divol, L.; Huntington, C. M.; Park, H.-S. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States)

    2014-11-15

    Imaging Thomson scattering measurements of collective ion-acoustic fluctuations have been utilized to determine ion temperature and density from laser produced counter-streaming asymmetric flows. Two foils are heated with 8 laser beams each, 500 J per beam, at the Omega Laser facility. Measurements are made 4 mm from the foil surface using a 60 J 2ω probe laser with a 200 ps pulse length. Measuring the electron density and temperature from the electron-plasma fluctuations constrains the fit of the multi-ion species, asymmetric flows theoretical form factor for the ion feature such that the ion temperatures, ion densities, and flow velocities for each plasma flow are determined.

  7. Turbulent flow through two asymmetric rod bundles

    International Nuclear Information System (INIS)

    Measurements of the mean velocity, of the wall shear stresses, and of the turbulence have been performed in four wall subchannels of rod bundles of four parallel rods enclosed in a rectangular channel. The pitch-to-diameter ratio was P/D=1.148 and the wall-to-diameter ratios ranged from 1.045 to 1.252. The full Reynolds stress tensor has been determined by hot-wire technique. The results of the turbulences intensities show that the flow through rod bundles differs widely from flow through circular tubes. More sophisticated analytical tools than presently available are required to predict turbulent flow through rod bundles with sufficient accuracy

  8. Effect of poloidally asymmetric sheared flow on resistive ballooning turbulence

    International Nuclear Information System (INIS)

    The shear flow induced through the Reynolds stress tensor by turbulence with ballooning character is poloidally asymmetric. For circular cross section tokamak plasmas, its main component is the (m=1, n=0). The effect of such a sheared flow on both linear and nonlinear instability is analyzed. Its effect on the linear stability properties of resistive ballooning modes is compared with the effect of poloidally symmetric sheared flows. It is shown that asymmetry in the flow does not reduce its effectiveness in stabilizing the linear resistive ballooning modes. It is also effective in reducing the turbulence level and decreasing the turbulence induced diffusivities. copyright 1999 American Institute of Physics

  9. Breakdown of doublet recirculation and direct line drives by far-field flow in reservoirs: implications for geothermal and hydrocarbon well placement

    Science.gov (United States)

    Weijermars, R.; van Harmelen, A.

    2016-07-01

    An important real world application of doublet flow occurs in well design of both geothermal and hydrocarbon reservoirs. A guiding principle for fluid management of injection and extraction wells is that mass balance is commonly assumed between the injected and produced fluid. Because the doublets are considered closed loops, the injection fluid is assumed to eventually reach the producer well and all the produced fluid ideally comes from stream tubes connected to the injector of the well pair making up the doublet. We show that when an aquifer background flow occurs, doublets will rarely retain closed loops of fluid recirculation. When the far-field flow rate increases relative to the doublet's strength, the area occupied by the doublet will diminish and eventually vanishes. Alternatively, rather than using a single injector (source) and single producer (sink), a linear array of multiple injectors separated by some distance from a parallel array of producers can be used in geothermal energy projects as well as in waterflooding of hydrocarbon reservoirs. Fluid flow in such an arrangement of parallel source-sink arrays is shown to be macroscopically equivalent to that of a line doublet. Again, any far-field flow that is strong enough will breach through the line doublet, which then splits into two vortices. Apart from fundamental insight into elementary flow dynamics, our new results provide practical clues that may contribute to improve the planning and design of doublets and direct line drives commonly used for flow management of groundwater, geothermal and hydrocarbon reservoirs.

  10. Breakdown of doublet re-circulation and direct line drives by far-field flow in reservoirs: Implications for geothermal and hydrocarbon well placement

    Science.gov (United States)

    Weijermars, R.; van Harmelen, A.

    2016-04-01

    An important real world application of doublet flow occurs in well design of both geothermal and hydrocarbon reservoirs. A guiding principle for fluid management of injection and extraction wells is that mass balance is commonly assumed between the injected and produced fluid. Because the doublets are considered closed loops, the injection fluid is assumed to eventually reach the producer well and all the produced fluid ideally comes from stream tubes connected to the injector of the well pair making up the doublet. We show that when an aquifer background flow occurs, doublets will rarely retain closed loops of fluid re-circulation. When the far-field flow rate increases relative to the doublet's strength, the area occupied by the doublet will diminish and eventually vanishes. Alternatively, rather than using a single injector (source) and single producer (sink), a linear array of multiple injectors separated by some distance from a parallel array of producers can be used in geothermal energy projects as well as in waterflooding of hydrocarbon reservoirs. Fluid flow in such an arrangement of parallel source-sink arrays is shown to be macroscopically equivalent to that of a line doublet. Again, any far-field flow that is strong enough will breach through the line doublet, which then splits into two vortices. Apart from fundamental insight into elementary flow dynamics, our new results provide practical clues that may contribute to improve the planning and design of doublets and direct line drives commonly used for flow management of groundwater, geothermal and hydrocarbon reservoirs.

  11. Asymmetric Accretion Flows within a Common Envelope

    CERN Document Server

    MacLeod, Morgan

    2014-01-01

    This paper examines flows in the immediate vicinity of stars and compact objects dynamically inspiralling within a common envelope (CE). These embedded objects spiral to tighter separations because of drag that is generated when gas collides and shocks as it is gravitationally focused. This flow convergence is expected to lead to gas accretion onto the inspiralling object. This process has been studied numerically and analytically in the context of Hoyle-Lyttleton accretion (HLA). Yet, within a CE, accretion structures may span a large fraction of the envelope radius, and in so doing sweep across a substantial radial gradient of density. We quantify these gradients using detailed stellar evolution models for a range of CE encounters. We provide estimates of typical scales in CE encounters that involve main sequence stars, white dwarfs, neutron stars, and black holes with giant-branch companions of a wide range of masses. We apply these typical scales to hydrodynamic simulations of 3D HLA with an upstream dens...

  12. Elliptic and triangular flow in asymmetric heavy-ion collisions

    International Nuclear Information System (INIS)

    We present a study of the elliptic (v2) and triangular (v3) flow and their corresponding eccentricity fluctuations for asymmetric (Au+Ag, Au+Cu, and Au+Si) collisions at √(sNN) = 200 GeV. These are compared to the corresponding results from symmetric (Au+Au and Cu+Cu) collisions at the same energy. The study which is carried out using a multiphase transport (AMPT) model shows that triangularity (ε3), fluctuations in triangularity and v3 do not show much variation for the different colliding ion sizes studied. However the eccentricity (ε2), fluctuations in eccentricity and v2, shows a strong dependence on colliding ion size for a given number of participating nucleons. Our study thus indicates that asymmetric heavy-ion collisions could be used to constrain models dealing with flow fluctuations in heavy-ion collisions.

  13. Elliptic and Triangular flow in asymmetric heavy-ion collisions

    CERN Document Server

    Haque, Md Rihan; Mohanty, Bedangadas

    2011-01-01

    We present a study of the elliptic (v2) and triangular (v3) flow and their corresponding eccentricity fluctuations for asymmetric (Au+Ag, Au+Cu and Au+Si) collisions at \\sqrt_NN = 200 GeV. These are compared to the corresponding results from symmetric (Au+Au and Cu+Cu) collisions at the same energy. The study which is carried out using a multi-phase transport (AMPT) model shows that triangularity (\\epsilon_3), fluctuations in triangularity and v3 do not show much variation for the different colliding ion sizes studied. However the eccentricity (\\epsilon_2), fluctuations in eccentricity and v2 shows a strong dependence on colliding ion size for a given number of participating nucleons. Our study thus indicates that asymmetric heavy-ion collisions could be used to constrain models dealing with flow fluctuations in heavy-ion collisions.

  14. Analysis of humic colloid borne trace elements by flow field-flow fractionation, gel permeation chromatography and icp-mass spectrometry

    International Nuclear Information System (INIS)

    Groundwater samples containing aquatic humic substances are analyzed by flow field- flow fractionation (FFFF) and gel permeation chromatography (GPC). Natural concentrations of U, Th and rare earth elements (REE) in a size-fractionated groundwater sample are analyzed by on-line coupling of inductively coupled plasma-mass spectrometry (ICP-MS) to either FFFF or GPC. The uranium, thorium, and REE are found to be quantitatively attached to colloidal species in the investigated groundwater sample. Their distribution in different colloid size fractions, however, is quite heterogeneous. Both, FFFF and GPC reveal that Th and REE are preferentially located in the size fraction > 50 kDalton. U is also attached to low molecular weight humic acid, similar to Fe and Al. This finding could be qualitatively reproduced by sequential ultrafiltration. The results are interpreted in terms of different binding mechanisms for the individual elements in the heterogeneous humic macromolecules. The inclusion of actinides into larger aggregates of aquatic humic acid might explain the considerable kinetic hindrance of actinide-humic acid dissociation reactions described in the literature. (authors)

  15. Chemical speciation studies on DU contaminated soils using flow field flow fractionation linked to inductively coupled plasma mass spectrometry (FlFFF-ICP-MS).

    Science.gov (United States)

    Brittain, S R; Cox, A G; Tomos, A D; Paterson, E; Siripinyanond, A; McLeod, C W

    2012-03-01

    Flow field flow fractionation (FlFFF) in combination with inductively coupled plasma mass spectrometry (ICP-MS) was used to study the chemical speciation of U and trace metals in depleted uranium (DU) contaminated soils. A chemical extraction procedure using sodium pyrophosphate, followed by isolation of humic and fulvic substances was applied to two dissimilar DU contaminated sample types (a sandy soil and a clay-rich soil), in addition to a control soil. The sodium pyrophosphate fractions of the firing range soils (Eskmeals and Kirkcudbright) were found to contain over 50% of the total U (measured after aqua regia digestion), compared to approximately 10% for the control soil. This implies that the soils from the contaminated sites contained a large proportion of the U within more easily mobile soil fractions. Humic and fulvic acid fractions each gave characteristic peak maxima for analytes of interest (Mn, Fe, Cu, Zn, Pb and U), with the fulvic acid fraction eluting at a smaller diameter (approximately 2.1 nm on average) than the humic fraction (approximately 2.4 nm on average). DU in the fulvic acid fraction gave a bimodal peak, not apparent for other trace elements investigated, including natural U. This implies that DU interacts with the fulvic acid fraction in a different way to all other elements studied. PMID:22237634

  16. On the wake flow of asymmetrically beveled trailing edges

    Science.gov (United States)

    Guan, Yaoyi; Pröbsting, Stefan; Stephens, David; Gupta, Abhineet; Morris, Scott C.

    2016-05-01

    Trailing edge and wake flows are of interest for a wide range of applications. Small changes in the design of asymmetrically beveled or semi-rounded trailing edges can result in significant difference in flow features which are relevant for the aerodynamic performance, flow-induced structural vibration and aerodynamically generated sound. The present study describes in detail the flow field characteristics around a family of asymmetrically beveled trailing edges with an enclosed trailing-edge angle of 25° and variable radius of curvature R. The flow fields over the beveled trailing edges are described using data obtained by particle image velocimetry (PIV) experiments. The flow topology for different trailing edges was found to be strongly dependent on the radius of curvature R, with flow separation occurring further downstream as R increases. This variation in the location of flow separation influences the aerodynamic force coefficients, which were evaluated from the PIV data using a control volume approach. Two-point correlations of the in-plane velocity components are considered to assess the structure in the flow field. The analysis shows large-scale coherent motions in the far wake, which are associated with vortex shedding. The wake thickness parameter yf is confirmed as an appropriate length scale to characterize this large-scale roll-up motion in the wake. The development in the very near wake was found to be critically dependent on R. In addition, high-speed PIV measurements provide insight into the spectral characteristics of the turbulent fluctuations. Based on the time-resolved flow field data, the frequency range associated with the shedding of coherent vortex pairs in the wake is identified. By means of time-correlation of the velocity components, turbulent structures are found to convect from the attached or separated shear layers without distinct separation point into the wake.

  17. Dynamic properties of asymmetric discrete vortex-flow transistors

    International Nuclear Information System (INIS)

    The dynamic properties of discrete vortex-flow transistors (DVFTs) comprised of a parallel array of ten Josephson junctions with asymmetric bias-current configurations have been studied numerically. Using parameters typical of high-temperature superconductor junctions at liquid-nitrogen temperatures, we show explicitly that the asymmetric-inline geometry, while it has the advantage of large (low-frequency) current gain (of order 50) and peak transresistance (of order 10 Ω), is inherently limited by slow vortex transit times (of order 100 ps) which result from the absence of Lorentz forces on vortices moving in the structure. We also explain the extremely small dynamic range of the high-gain regime seen in the simulations here and observed experimentally in the literature. As the device symmetry is increased, faster transit times and a significant increase in dynamic range are observed. These results have direct impact on the feasibility of these devices as high-frequency amplifiers. (author)

  18. Comparison of the molecular mass and optical properties of colored dissolved organic material in two rivers and coastal waters by flow field-flow fractionation.

    Science.gov (United States)

    Zanardi-Lamardo, Eliete; Clark, Catherine D; Moore, Cynthia A; Zika, Rod G

    2002-07-01

    Colored dissolved organic material (CDOM) is an important sunlight absorbing substance affecting the optical properties of natural waters. However, little is known about its structural and optical properties mainly due to its complex matrix and the limitation of the techniques available. A comparison of two southwestern Florida rivers [the Caloosahatchee River (CR) and the Shark River (SR)] was done in terms of molecular mass (MM) and diffusion coefficients (D). The novel technique Frit inlet/frit outlet-flow field-flow fractionation (FIFO-FIFFF) with absorbance and fluorescence detectors was used to determine these properties. The SR receives organic material from the Everglades. By contrast, the CR arises from Lake Okeechobee in central Florida, receiving anthropogenic inputs, farming runoff, and natural organics. Both rivers discharge to the Gulf of Mexico. Fluorescence identified, for both rivers, two different MM distributions in low salinity water samples: the first was centered at approximately 1.7 kDa (CR) and approximately 2 kDa (SR); the second centered at approximately 13 kDa for both rivers, which disappeared gradually in the river plumes to below detection limit in coastal waters. Absorbance detected only one MM distribution centered at approximately 2 kDa (CR) and 2.2-2.4 kDa (SR). Fluorescence in general peaked at a lower MM than absorbance, suggesting a different size distribution for fluorophores vs chromophores. A photochemical study showed that, after sunlight, irradiated freshwater samples have similar characteristics to more marine waters, including a shift in MM distribution of chromophores. The differences observed between the rivers in the optical characteristics, MM distributions, and D values suggest that the CDOM sources, physical, and photochemical degradation processes are different for these two rivers. PMID:12144250

  19. Size-based speciation of iron in clay mineral particles by gravitational field-flow fractionation with electrothermal atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Gravitational field-flow fractionation (FFF) coupled to UV and ETAAS detectors has been tested for micron-size particles in the range of 5-20 μm using three Fe-rich clay samples. The iron content estimated after aqua regia extraction was about 20-40 mg kg-1. The ETAAS analysis was performed both off-line from collected fractions and in an online continuous sampling mode using a specially designed flow through vial placed in the autosampler of the ETAAS. Comparison of the direct injection method with total analysis after aqua regia digestion shows that slurry injection of the dilute samples in the gravitational field-flow fractionation (GrFFF) effluent is quite efficient in these samples. In the majority of cases, more than 90% recovery was obtained for the slurry injection method. Fe mass-based particle size distributions and Fe concentration versus particle diameter plots can be generated using certain assumptions. This provides detailed information on size-based speciation of particulate samples. Generally, the Fe concentrations in the particles decreased slightly with an increase in particle size as is often found for soil and sediment samples

  20. Elimination of edge effects in micro-thermal field-flow fractionation channel of low aspect ratio by splitting the carrier liquid flow into the main central stream and the thin stream layers at the side channel walls

    Czech Academy of Sciences Publication Activity Database

    Janča, J.; Dupák, Jan

    2005-01-01

    Roč. 1068, č. 2 (2005), s. 261-268. ISSN 0021-9673 Institutional research plan: CEZ:AV0Z20650511 Keywords : Micro-thermal field-flow fractionation * Edge effects * Inlet and outlet hydrodynamic splitting * New injection mode Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.096, year: 2005

  1. Up-down asymmetric tokamak equilibria with parallel flows

    International Nuclear Information System (INIS)

    A class of exact axisymmetric tokamak equilibria with sheared flows parallel to the magnetic field is constructed, generalizing previous work on the subject (Kuiroukidis 2010 Plasma Phys. Control. Fusion 52 015002). The additional free parameters associated with new terms in the solution make it possible to construct up–down asymmetric configurations with a divertor X-point and desirable values of confinement figures of merit as the safety factor on the magnetic axis and plasma betas; in particular, we construct a number of ITER-pertinent equilibria. Their stability with respect to linear MHD perturbations is also examined by applying a sufficient condition.

  2. EFFECTS OF ASYMMETRIC FLOWS IN SOLAR CONVECTION ON OSCILLATION MODES

    International Nuclear Information System (INIS)

    Many helioseismic measurements suffer from substantial systematic errors. A particularly frustrating one is that time-distance measurements suffer from a large center to limb effect which looks very similar to the finite light travel time, except that the magnitude depends on the observable used and can have the opposite sign. This has frustrated attempts to determine the deep meridional flow in the solar convection zone, with Zhao et al. applying an ad hoc correction with little physical basis to correct the data. In this Letter, we propose that part of this effect can be explained by the highly asymmetrical nature of the solar granulation which results in what appears to the oscillation modes as a net radial flow, thereby imparting a phase shift on the modes as a function of observing height and thus heliocentric angle.

  3. Charge-dependent directed flow in asymmetric nuclear collisions

    CERN Document Server

    Voronyuk, V; Voloshin, S A; Cassing, W

    2014-01-01

    The directed flow of identified hadrons is studied within the parton-hadron-string-dynamics (PHSD) approach for the asymmetric system Cu+Au in non-central collisions at $\\sqrt{s_{NN}}$ = 200 GeV. It is emphasized that due to the difference in the number of protons of the colliding nuclei an electric field emerges which is directed from the heavy to the light nucleus. This strong electric field is only present for about 0.25 fm/c at $\\sqrt{s_{NN}}$ = 200 GeV and leads to a splitting of the directed flow $v_1$ for particles with the same mass but opposite electric charges in case of an early presence of charged quarks and antiquarks. The microscopic calculations of the directed flow for $\\pi^\\pm, K^\\pm, p$ and $\\bar{p}$ are carried out in the PHSD by taking into account the electromagnetic field induced by the spectators as well as its influence on the hadronic and partonic quasiparticle trajectories. It is shown that the splitting of the directed flow as a function of pseudorapidity $\\eta$ and in particular as...

  4. On Cauchy conditions for asymmetric mixed convection boundary layer flows

    Energy Technology Data Exchange (ETDEWEB)

    Amaouche, Mustapha [Laboratoire de Physique Theorique, Universite de Bejaia (Algeria); Kessal, Mohand [Departement Transport et Equipement Petrolier, Faculte des Hydrocarbures et de la Chimie, Universite de Boumerdes, 35000, Boumerdes (Algeria)

    2003-06-01

    The fundamental question of how and where does an asymmetric mixed convection boundary layer flow around a heated horizontal circular cylinder begin to develop is raised. We first transform the classical boundary layer equations by using an integral method of Karman-Pohlhausen type and obtain two coupled equations governing the evolutions of the dynamic and thermal boundary layers. Because of its global character, the implemented method allows to bypass the difficulty of downstream-upstream interactions. Cauchy conditions characterizing the starting of the boundary layers are found; they are obtained in a surprisingly simple manner for the limiting cases corresponding to Pr=1, Pr{yields}0 and Pr{yields}{infinity}. Otherwise, these conditions can be found by using a prediction correction algorithm. Some numerical experiments are finally performed in order to illustrate the theory. (authors)

  5. Edge Detection from MRI and DTI Images with an Anisotropic Vector Field Flow Using a Divergence Map

    Directory of Open Access Journals (Sweden)

    Donatella Giuliani

    2012-12-01

    Full Text Available The aim of this work is the extraction of edges from Magnetic Resonance Imaging (MRI and Diffusion Tensor Imaging (DTI images by a deformable contour procedure, using an external force field derived from an anisotropic flow. Moreover, we introduce a divergence map in order to check the convergence of the process. As we know from vector calculus, divergence is a measure of the magnitude of a vector field convergence at a given point. Thus by means level curves of the divergence map, we have automatically selected an initial contour for the deformation process. If the initial curve includes the areas from which the vector field diverges, it will be able to push the curve towards the edges. Furthermore the divergence map highlights the presence of curves pointing to the most significant geometric parts of boundaries corresponding to high curvature values. In this way, the skeleton of the extracted object will be rather well defined and may subsequently be employed in shape analysis and morphological studies.

  6. Three-dimensional computational study of asymmetric flows using Navier-Stokes equations

    Science.gov (United States)

    Cheung, Y. K. (Editor); Lee, J. H. W. (Editor); Leung, A. Y. T. (Editor); Wong, Tin-Chee; Kandil, Osama A.; Liu, C. H.

    1992-01-01

    The unsteady, compressible, thin-layer Navier-Stokes equations are used to obtain three-dimensional, asymmetric, vortex-flow solutions around cones and cone-cylinder configurations. The equations are solved using an implicit, upwind, flux-difference splitting, finite-volume scheme. The computational applications cover asymmetric flows around a 5 semi-apex angle cone of unit length at various Reynolds number. Next, a cylindrical afterbody of various length is added to the conical forebody to study the effect of the length of cylindrical afterbody on the flow asymmetry. All the asymmetric flow solutions are obtained by using a short-duration side-slip disturbance.

  7. Notes on the implementation of a fully-implicit numerical scheme for a two-phase three-field flow model

    International Nuclear Information System (INIS)

    The development of a fully-implicit scheme to model the two-phase three-field flow and heat transfer problem is presented here. The model was originally developed to simulate the complex phenomena occurring in proximity of the quench front of a nuclear reactor core during the reflood phase of a postulated LOCA. The fully-implicit method allows relative large time steps to be used even on very fine spatial grids which can not be considered when a semi-implicit scheme is applied to solve the conservation equation. The objective of this paper is to capture as much as possible, the lessons learned during the development and coding of the fully-implicit two-phase three-field model. The implementation of the model is one of the most time consuming and a challenging task. The literature on numerical models generally concentrates on the theoretical aspects of the numerical method but available information on the problems encountered during the implementation of such methods for real applications is scarce. The reason is that many of these methods are tailored to specific applications and sometimes are rather empirical. These techniques are the result of a long and tedious trial and error process from the developer. The article presented here attempts to provide some insights and guidelines for future development of this or similar models

  8. Asymmetric magnetic reconnection with out-of-plane shear flows in a two dimensional hybrid model

    International Nuclear Information System (INIS)

    Effects of out-of-plane shear flows on asymmetric magnetic reconnect are investigated in a two-dimensional (2D) hybrid model with an initial Harris sheet equilibrium. It is found that the out-of-plane flow with an in-plane shear can significantly change the asymmetric reconnection process as well as the related geometry. The magnetic flux, out-of-plane magnetic field, in-plane flow vorticity, plasma density, and the reconnection rate are discussed in detail. The results are in comparison with the cases without the shear flows to further understand the effect

  9. Controlling the flow of information in quantum cloners: asymmetric cloning

    International Nuclear Information System (INIS)

    We show that the distribution of information at the output of the quantum cloner can be efficiently controlled via preparation of the quantum cloner. We present a universal cloning network with the help of which asymmetric cloning can be performed. (author)

  10. Feasibility of asymmetric flow field-flow fractionation coupled to ICP-MS for the characterization of wear metal particles and metalloproteins in biofluids from hip replacement patients

    DEFF Research Database (Denmark)

    Löschner, Katrin; Harrington, Chris F.; Kearney, Jacque-Lucca;

    2015-01-01

    with inductively coupled plasma mass spectrometry (ICP-MS) was used to investigate metal protein binding and the size and composition of wear metal particles present in serum and hip aspirates from MoM hip replacement patients. A well-established HPLC anion exchange chromatography (AEC) separation...... system coupled to ICP-MS was used to confirm the metal–protein associations in the serum samples. Off-line single particle ICP-MS (spICP-MS) analysis was used to confirm the approximate size distribution indicated by AF4 of the wear particles in hip aspirates. In the serum samples, AF4–ICP-MS suggested...... associated with Alb and two unidentified compounds; AEC analysis confirmed the Cr results and the association of Co with Alb and a second compound. Enzymatic digestion of the hip aspirate sample, followed by separation using AF4 with detection by UV absorption (280 nm), multi-angle light scattering and ICP-MS...

  11. Detection and characterization of silver nanoparticles in chicken meat by asymmetric flow field flow fractionation with detection by conventional or single particle ICP-MS

    DEFF Research Database (Denmark)

    Löschner, Katrin; Navratilova, Jana; Købler, Carsten;

    2013-01-01

    A method of analysis of silver nanoparticles (AgNPs) in chicken meat was developed. The homogenized chicken meat sample, which was spiked with AgNPs, was subjected to enzymolysis by Proteinase K for 40 min at 37 °C. Transmission electron microscopy and inductively coupled plasma mass spectrometry...... ICP-MS was applied for determination of the number-based particle size distribution of AgNPs in collected fractions. The presented work describes for the first time the coupling of AF(4) and ICP-MS for AgNP separation in a food matrix....

  12. Combining asymmetrical flow field-flow fractionation with light-scattering and inductively coupled plasma mass spectrometric detection for characterization of nanoclay used in biopolymer nanocomposites

    DEFF Research Database (Denmark)

    Schmidt, Bjørn; Petersen, Jens Højslev; Koch, C. Bender;

    2009-01-01

    It is expected that biopolymers obtained from renewable resources will in due course become fully competitive with fossil fuel-derived plastics as food-packaging materials. In this context, biopolymer nanocomposites are a field of emerging interest since such materials can exhibit improved...... mechanical and barrier properties and be more suitable for a wider range of food-packaging applications. Natural or synthetic clay nanofillers are being investigated for this purpose in a project called NanoPack funded by the Danish Strategic Research Council. In order to detect and characterize the size of...... polylactide (PLA) with 5% Cloisite®30B (a derivatized montmorillonite clay) as a filler. Based on AF4-MALS analyses, we found that particles ranging from 50 to 800 nm in radius indeed migrated into the 95% ethanol used as a food simulant. The full hyphenated AF4-MALS-ICP-MS system showed, however, that none...

  13. Asymmetric Flow Field Flow Fractionation Online with Single Particle – Inductively Coupled Plasma Mass Spectrometry: Detection and Quantification of Silver Nanoparticles in Aqueous Samples

    Science.gov (United States)

    Silver nanoparticles (AgNPs) are increasingly being used in many consumer products as disinfectants. Through the use of these products, AgNPs could likely enter aquatic environments. Because recent studies have shown that AgNPs are toxic to various species, including microorgan...

  14. Asymmetric Flow-Field Flow Fractionation (AF4) of Aqueous C60 Aggregates with Dynamic Light Scattering Size and LC-MS

    Science.gov (United States)

    Current methods for the size determination of nanomaterials in aqueous suspension include dynamic or static light scattering and electron or atomic force microscopy techniques. Light scattering techniques are limited by poor resolution and the scattering intensity dependence on p...

  15. 重力场流分离系统中载液及流速条件对分离的影响%Effects of carrier liquid and flow rate on the separation in gravitational field-flow fractionation

    Institute of Scientific and Technical Information of China (English)

    郭爽; 朱尘琪; 高杨亚雅; 邱百灵; 吴迪; 梁启慧; 何嘉媛; 韩南银

    2016-01-01

    Gravitational field-flow fractionation is the simplest field-flow fractionation technique in terms of principle and operation. The earth's gravity is its external field. Different sized par-ticles are injected into a thin channel and carried by carrier fluid. The different velocities of the carrier liquid in different places results in a size-based separation. A gravitational field-flow frac-tionation(GrFFF)instrument was designed and constructed. Two kinds of polystyrene(PS) particles with different sizes(20 μm and 6 μm)were chosen as model particles. In this work, the separation of the sample was achieved by changing the concentration of NaN 3,the percent-age of mixed surfactant in the carrier liquid and the flow rate of carrier liquid. Six levels were set for each factor. The effects of these three factors on the retention ratio( R)and plate height ( H)of the PS particles were investigated. It was found that R increased and H decreased with increasing particle size. On the other hand,the R and H increased with increasing flow rate. The R and H also increased with increasing NaN 3 concentration. The reason was that the elec-trostatic repulsive force between the particles and the glass channel wall increased. The force allowed the samples approach closer to the channel wall. The results showed that the resolution and retention time can be improved by adjusting the experimental conditions. These results can provide important values to the further applications of GrFFF technique.%重力场流分离作为最简单的一种场流分离技术,常用于分离微米级颗粒.选择两种不同粒径( 20 μm 和 6μm)的聚苯乙烯( PS)颗粒作为样品,通过改变载液中叠氮化钠浓度、混合表面活性剂的比例及载液流速,利用自行设计生产的重力场流分离( gravitational flow field-flow fractionation,GrFFF)仪器,对颗粒混合样品进行分离,得到了相关谱图与数据,考察了这3种因素对分离效果(保留比( R

  16. Vibration testing and analysis of core barrel model in symmetrical/asymmetrical liquid flow conditions

    International Nuclear Information System (INIS)

    This paper presents the results of vibration tests of PWR core barrel model, which were performed in liquid flow of hydrodynamic testing circuit in symmetrical/asymmetrical flow conditions simulating 4 and 3 loop operations. The measurements of dynamic stresses and displacements were carried out, processed stochastically and analyzed by correlation techniques

  17. Study of flow in asymmetric heavy-ion collisions

    International Nuclear Information System (INIS)

    Azimuthal anisotropy is a key tool to study the strongly interacting medium produced in relativistic heavy ion collisions. This observable is sensitive to the equation of state of the system formed in the heavy-ion collisions. Recently, it has been proposed at the Relativistic Heavy Ion Collider, to carry out a program of asymmetric heavy-ion collisions. Among other physics possibilities, it is believed to provide insight on the initial conditions through study of event-by-event fluctuation in the measure of the azimuthal anisotropy. Knowing the initial condition is vital for any theoretical calculations in relativistic heavy-ion collisions

  18. Observational signatures of loop flows driven by asymmetric heating

    International Nuclear Information System (INIS)

    The observational consequences of highly asymmetric heating in small transition-region loops is studied using time-dependent numerical simulations. It is found that the plasma at C IV-emitting temperatures appears to be redshifted to an observer looking down on the loop. It is shown that the observation of a blueshifted emission line in the upper transition region of the sun or other late-type stars may not be evidence for the initial acceleration of the solar wind, but rather part of a closed circulation system. 13 references

  19. Some asymmetric thermohydraulic behaviors of liquid metal-gas two-phase MHD flows

    International Nuclear Information System (INIS)

    In this paper magnetohydrodynamic effect on liquid-metal two-phase flow and heat transfer are summarized based on the measurements made by the present author in NaK-nitrogen flow in a vertical round tube in the presence of a transverse magnetic field. This study covered a wide range of two-phase flow patterns from bubbly flow to annular-dispersed flow, including flow pattern observation, measurements of phase distributions, liquid film behavior, and heat transfer coefficient. Particular emphases are directed towards describing asymmetric thermohydraulic structures induced by the applied magnetic field

  20. Separation of silver nanoparticles by hollow fiber flow field-flow fractionation: Addition of tannic acid into carrier liquid as a modifier.

    Science.gov (United States)

    Saenmuangchin, Rattaporn; Mettakoonpitak, Jaruwan; Shiowatana, Juwadee; Siripinyanond, Atitaya

    2015-10-01

    A homemade hollow fiber flow-field fractionation (Hf-FlFFF) coupled with inductively coupled plasma mass spectrometry (ICP-MS) was set-up for silver nanoparticles (AgNPs) separation by using polysulfone hollow fiber membrane (30,000 MW cutoff) as a separation channel. Tannic acid and citrate stabilized AgNPs were synthesized and introduced into Hf-FlFFF. The effects of carrier liquid and stabilizing agent on retention behavior of AgNPs were investigated. Different elution behaviors were observed as follows: with 0.02% (w/v) FL-70, all of AgNPs were eluted from Hf-FlFFF but differences in retention behaviors were observed for AgNPs with tannic acid and citrate stabilizing agents; and with 30mM TRIS buffer, only tannic acid stabilized AgNPs were eluted from Hf-FlFFF, whereas citrate stabilized AgNPs were not eluted. In this work, tannic acid addition into carrier liquid was proposed to modify the surface of AgNPs and the surface of the membrane, and thereby adjusting the retention behaviors of AgNPs. Various concentrations of tannic acid were added into FL-70 and TRIS buffer. With the use of 0.1mM tannic acid in 30mM TRIS buffer as the carrier liquid, retention behaviors of both tannic acid stabilized- and citrate stabilized-AgNPs were similar and with similar fractionation recovery. PMID:26341593

  1. Asymmetric energy flow in liquid alkylbenzenes: A computational study

    International Nuclear Information System (INIS)

    Ultrafast IR-Raman experiments on substituted benzenes [B. C. Pein et al., J. Phys. Chem. B 117, 10898–10904 (2013)] reveal that energy can flow more efficiently in one direction along a molecule than in others. We carry out a computational study of energy flow in the three alkyl benzenes, toluene, isopropylbenzene, and t-butylbenzene, studied in these experiments, and find an asymmetry in the flow of vibrational energy between the two chemical groups of the molecule due to quantum mechanical vibrational relaxation bottlenecks, which give rise to a preferred direction of energy flow. We compare energy flow computed for all modes of the three alkylbenzenes over the relaxation time into the liquid with energy flow through the subset of modes monitored in the time-resolved Raman experiments and find qualitatively similar results when using the subset compared to all the modes

  2. Asymmetric energy flow in liquid alkylbenzenes: A computational study

    Energy Technology Data Exchange (ETDEWEB)

    Leitner, David M., E-mail: dml@unr.edu [Department of Chemistry and Chemical Physics Program, University of Nevada, Reno, Nevada 89557 (United States); Freiburg Institute for Advanced Studies (FRIAS), Freiburg (Germany); Pandey, Hari Datt [Department of Chemistry and Chemical Physics Program, University of Nevada, Reno, Nevada 89557 (United States)

    2015-10-14

    Ultrafast IR-Raman experiments on substituted benzenes [B. C. Pein et al., J. Phys. Chem. B 117, 10898–10904 (2013)] reveal that energy can flow more efficiently in one direction along a molecule than in others. We carry out a computational study of energy flow in the three alkyl benzenes, toluene, isopropylbenzene, and t-butylbenzene, studied in these experiments, and find an asymmetry in the flow of vibrational energy between the two chemical groups of the molecule due to quantum mechanical vibrational relaxation bottlenecks, which give rise to a preferred direction of energy flow. We compare energy flow computed for all modes of the three alkylbenzenes over the relaxation time into the liquid with energy flow through the subset of modes monitored in the time-resolved Raman experiments and find qualitatively similar results when using the subset compared to all the modes.

  3. Transient Asymmetric Flow and Bubble Transport Inside a Slab Continuous-Casting Mold

    Science.gov (United States)

    Liu, Zhongqiu; Li, Baokuan; Jiang, Maofa

    2014-04-01

    A one third scale water model experiment was conducted to observe the asymmetric flow and vortexing flow inside a slab continuous-casting mold. Dye-injection experiment was used to show the evolution of the transient flow pattern in the liquid pool without and with gas injection. The spread of the dye was not symmetric about the central plane. The flow pattern inside the mold was not stationary. The black sesames were injected into water to visualize the vortexing flow pattern on the top surface. The changes of shape and location of single vortex and two vortices with time had been observed during experiments. Plant ultrasonic testing (UT) of slabs was used to analyze the slab defects distribution, which indicated that the defects are intermittent and asymmetric. A mathematical model has been developed to analyze the time-dependent flow using the realistic geometries, which includes the submerged entry nozzle (SEN), actual mold, and part of the secondary cooling zone. The transient turbulent flow of molten steel inside the mold has been simulated using the large eddy simulation computational approach. Simulation results agree acceptably well with the water model experimentally observed and plant UT results. The oscillating motions of jet and the turbulence naturally promote the asymmetric flow even without the effects of slide gate nozzle or the existence of clogs inside the SEN. The periodic behavior of transient fluid flow in the mold is identified and characterized. The vortexing flow is resulted from asymmetric flow in the liquid pool. The vortices are located at the low-velocity side adjacent to the SEN, and the positions and sizes are different. Finally, the model is applied to investigate the influence of bubble size and casting speed on the time-dependent bubble distribution and removal fraction from the top surface inside the mold.

  4. Directed transverse flow and its disappearance for asymmetric reactions

    International Nuclear Information System (INIS)

    We study the directed transverse flow for mass asymmetry reactions. This is done by keeping the target fixed and varying the projectile mass from 4He to 131Xe. We find that directed transverse flow is sensitive to the mass of the projectile. We also study the disappearance of flow at a particular impact parameter called Geometry of Vanishing Flow (GVF) for such mass asymmetry reactions. Our results indicate that GVF is sensitive to the beam energy as well as to the mass of the projectile.

  5. Stability characteristics of the open channel flow above the asymmetrical irregular sand ripples

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Sandy bed cannot keep its original smoothness as the flows pass. With the increase of the flow intensity, the bed forms will appear as sand ripples and dune in turn. Among these morphologies, the sand ripple scale is the smallest, which is generally symmetrical when it just appears, but as time goes on, the asymmetrical form gradually develops. Just because of this sand ripples asymmetry, it manifests the influence of the flow on the bed morphology and also the impact on the laminar flow dynamical process, especially the stability characteristics. The stability features of laminar flow on open channels with the asymmetrical sand ripples are discussed, and also the results on the symmetrical sand ripples are compared in detail.

  6. Experimental Investigation of Flow Through an Asymmetrical Plane Diffuser

    Science.gov (United States)

    Buice, Carl U.; Eaton, John K.

    1996-01-01

    The objective of this study is to provide careful qualification and detailed measurements in a re-creation of the Obi experiment. The work will include extensive documentation of the flow two-dimensionality and detailed measurements required for testing of flow computations. Also important to this study is the close interaction of the experimental and computational groups to improve the utility of the data obtained and the accuracy of computation.

  7. DEM Simulation of Solid Flow Including Asymmetric Phenomena in COREX Shaft Furnace

    Institute of Scientific and Technical Information of China (English)

    Zhi-guo LUO; Heng ZHOU; Tao ZHANG; Yang YOU; Hai-feng LI; Zong-shu ZOU

    2015-01-01

    Based on the principles of the discrete element method (DEM),a scaled-down model was established to analyze burden descending behavior,including asymmetric phenomena,throughout an entire COREX shaft furnace (SF).The applicability of the DEM model was validated by determining its accordance with a previous experiment. The effects of discharge rate and abnormal conditions on solid flow were described in terms of solid flow pattern and microscopic analysis.Results confirmed that the solid flow of the COREX SF can be divided into four different flow regions;the largest normal force exists at the top of the man-made dead zone,and the weak force network exists in the funnel flow region.The basic solid flow profile was identified as a clear Flat→U→W type.Increasing the dis-charge rate decreased the quasi-stagnant zone size,but did not affect the macroscopic motion of particles or the shape of patterns above the bustle.For asymmetric conditions,in which particles were discharged at different rates,the solid flow patterns were asymmetric.Under an abnormal condition where no particles were discharged from the left outlet,a sizeable stagnant zone was formed opposite to the working outlet,and “motionless”particles located in the left stagnant zone showed potential to increase the period of static contacts and sticking effect.

  8. Simultaneous measurements of plasma flow and ion temperature using the asymmetric double probe

    International Nuclear Information System (INIS)

    The asymmetric double probe method is extended to measure not only the ion temperature but also plasma flow in the tokamak edge plasma under a strong magnetic field. The plasma flow or the Mach number is determined by the ratio of ion saturation currents of the double probe pins, where the axes of the cylindrical pins are oriented perpendicular to the magnetic field and face up-or downstream. An experiment was performed in the JFT-2M tokamak. (author)

  9. Reynolds number effects on supersonic asymmetrical flows over a cone at high angle of attack

    Science.gov (United States)

    Thomas, J. L.

    1991-01-01

    The supersonic viscous flow over a 5-degree half-angle cone at an angle of attack of four times the cone half-angle is studied computationally using both the conical and the three-dimensional Navier-Stokes equations. The numerical solutions were obtained with an implicit, upwind-biased algorithm. Asymmetrical flowfields of the absolute-instability type are found using the conical-flow equations which agree with published results. However, the absolute instabilities of the originally symmetric flow found with the conical equations do not occur in the three-dimensional simulations, although spurious asymmetric three-dimensional flows for symmetric bodies arise if the grid resolution is insufficient in the nose region. The asymmetric flows computed with the three-dimensional equations are convective instabilities and are possible if the local Reynolds number exceeds a critical value and a fixed geometric asymmetry is imposed. A continuous range of asymmetries can be developed, depending on the size of the disturbance and the Reynolds number. As the Reynolds number is increased, the asymmetries demonstrate a bistable behavior at levels of side force consistent with those predicted using the conical equations. Below a certain critical Reynolds number, any flow asymmetries arising from a geometrical asymmetry are damped with increasing distance downstream from the geometrical asymmetry.

  10. Design of vortex fluid amplifiers with asymmetrical flow fields.

    Science.gov (United States)

    Lawley, T. J.; Price, D. C.

    1972-01-01

    Variation of geometric parameters, including supply area, control area, chamber length, and outlet diameter, of a large scale, modular design vortex fluid amplifier with single supply and control jets, has confirmed and extended a previously published design method, developed for vortex amplifiers with symmetric flow fields. This allows application of the method to devices which are more representative of practical, production type components.

  11. Neckpinch dynamics for asymmetric surfaces evolving by mean curvature flow

    OpenAIRE

    Gang, Zhou; Knopf, Dan; Sigal, Israel Michael

    2011-01-01

    We study surfaces evolving by mean curvature flow (MCF). For an open set of initial data that are $C^3$-close to round, but without assuming rotational symmetry or positive mean curvature, we show that MCF solutions become singular in finite time by forming neckpinches, and we obtain detailed asymptotics of that singularity formation. Our results show in a precise way that MCF solutions become asymptotically rotationally symmetric near a neckpinch singularity.

  12. Tumbling of asymmetric microrods in a microchannel flow

    CERN Document Server

    Einarsson, J; Laas, A; Ankardal, S; Angilella, J R; Hanstorp, D; Mehlig, B

    2016-01-01

    We describe results of measurements of the orientational motion of glass microrods in a microchannel flow, following the orientational motion of particles with different shapes. We determine how the orientational dynamics depends on the shape of the particle and on its initial orientation. We find that the dynamics depends so sensitively on the degree to which axisymmetry is broken that it is difficult to find particles that are sufficiently axisymmetric so that they exhibit periodic tumbling ("Jeffery orbits").

  13. Local heat transfer in an in-line tube bundle with asymmetrical flow

    DEFF Research Database (Denmark)

    Meyer, Knud Erik

    Measurements of the local heat transfer in themiddle of a small in-line tube bundle with longitudinal to transverse pitches of $1.5\\times 1.8$ are performed at a Reynolds number of $30\\,000$. Asymmetrical distributions of the local heat transfer are found. The distributions are in good agreement ...... with earlier flow measurements. The mean heat transfer rate is only little affected bythe asymmetrical conditions.......Measurements of the local heat transfer in themiddle of a small in-line tube bundle with longitudinal to transverse pitches of $1.5\\times 1.8$ are performed at a Reynolds number of $30\\,000$. Asymmetrical distributions of the local heat transfer are found. The distributions are in good agreement...

  14. Symmetric and asymmetric solutions of oscillatory MHD flow due to eccentrically rotating disks

    International Nuclear Information System (INIS)

    Exact solutions are obtained for the unsteady MHD flow of a viscous, electrically conducting, homogeneous, incompressible fluid between two infinite parallel, insulated, porous disks rotating with angular velocity Ω about two non-coincident axes. The disks are subjected to non-torsional oscillations of different frequencies and a uniform magnetic field is applied normal to the disks. The asymmetric or symmetric solutions containing arbitary constants reduce to a single unique solution when one prescribes the pressure gradient. Necessary and sufficient conditions for a solution to be symmetric and asymmetric are obtained. In some special cases both the symmetric and asymmetric solutions for eccentrically rotating disks are evaluated numerically and discussed in detail. (author). 13 refs., 16 figs

  15. Particle-in-cell simulation study of the scaling of asymmetric magnetic reconnection with in-plane flow shear

    CERN Document Server

    Doss, C E; Swisdak, M

    2016-01-01

    We investigate magnetic reconnection in systems simultaneously containing asymmetric (anti-parallel) magnetic fields, asymmetric plasma densities and temperatures, and arbitrary in-plane bulk flow of plasma in the upstream regions. Such configurations are common in the high-latitudes of Earth's magnetopause and in tokamaks. We investigate the convection speed of the X-line, the scaling of the reconnection rate, and the condition for which the flow suppresses reconnection as a function of upstream flow speeds. We use two-dimensional particle-in-cell simulations to capture the mixing of plasma in the outflow regions better than is possible in fluid modeling. We perform simulations with asymmetric magnetic fields, simulations with asymmetric densities, and simulations with magnetopause-like parameters where both are asymmetric. For flow speeds below the predicted cutoff velocity, we find good scaling agreement with the theory presented in Doss et al., J.~Geophys.~Res., 120, 7748 (2015). Applications to planetary...

  16. Poloidal asymmetric flow and current relaxation of ballooned transport during I-phase in ASDEX Upgrade

    Science.gov (United States)

    Manz, P.; Birkenmeier, G.; Fuchert, G.; Cavedon, M.; Conway, G. D.; Maraschek, M.; Medvedeva, A.; Mink, F.; Scott, B. D.; Shao, L. M.; Stroth, U.

    2016-05-01

    Turbulence driven poloidal asymmetric parallel flow and current perturbations are studied for tokamak plasmas of circular geometry. Whereas zonal flows can lead to in-out asymmetry of parallel flows and currents via the Pfirsch-Schlüter mechanism, ballooned transport can result in an up-down asymmetry due to the Stringer spin-up mechanism. Measurements of up-down asymmetric parallel current fluctuations occurring during the I-phase in ASDEX Upgrade are not responses to the equilibrium by the Pfirsch-Schlüter current, but can be interpreted as a response to strongly ballooned plasma transport coupled with the Stringer spin-up mechanism. A good agreement of the experimental measured limit-cycle frequencies during I-phase with the Stringer spin-up relaxation frequency is found.

  17. Asymmetric collapse by dissolution or melting in a uniform flow

    CERN Document Server

    Rycroft, Chris H

    2015-01-01

    An advection--diffusion-limited dissolution model of an object being eroded by a two-dimensional potential flow is presented. By taking advantage of the conformal invariance of the model, a numerical method is introduced that tracks the evolution of the object boundary in terms of a time-dependent Laurent series. Simulations of a variety of dissolving objects are shown, which shrink and then collapse to a single point in finite time. The simulations reveal a surprising exact relationship whereby the collapse point is the root of a non-analytic function given in terms of the flow velocity and the Laurent series coefficients describing the initial shape. This result is subsequently derived using residue calculus. The structure of the non-analytic function is examined for three different test cases, and a practical approach to determine the collapse point using a generalized Newton--Raphson root-finding algorithm is outlined. These examples also illustrate the possibility that the model breaks down in finite tim...

  18. Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetric Flow Control—Part I: Non-Axisymmetrical Flow in Centrifugal Compressor

    OpenAIRE

    Yang, Mingyang; Zheng, Xinqian; Zhang, Yangjun; Bamba, Takahiro; Tamaki, Hideaki; Huenteler, Joern; Li, Zhigang

    2012-01-01

    This is Part I of a two-part paper documenting the development of a novel asymmetric flow control method to improve the stability of a high-pressure-ratio turbocharger centrifugal compressor. Part I focuses on the nonaxisymmetrical flow in a centrifugal compressor induced by the nonaxisymmetrical geometry of the volute while Part II describes the development of an asymmetric flow control method to avoid the stall on the basis of the characteristic of nonaxisymmetrical flow. To understand the ...

  19. A study of flow mixing in a PWR vessel in asymmetric cooldown faults using the FLOW3D code

    International Nuclear Information System (INIS)

    The Harwell computational fluid dynamics code, FLOW3D has been used to simulate a flow mixing test in the Oconee-1 reactor. The object was to test the ability of FLOW3D to describe thermal mixing in a PWR pressure vessel for the conditions of an over-cooling fault. The code produced reasonable estimates of the thermal diffusion observed in the Oconee test, with a tendency to underpredict mixing. However, the test exhibited gross swirl and asymmetric mixing which was not predicted by FLOW3D. Sensitivity studies to investigate the effects of downcomer ovality, inlet flow vorticity and flow imbalance between loops, have not revealed the source of the observed asymmetries

  20. ECCD control of dynamics of asymmetric magnetic islands in a sheared flow

    International Nuclear Information System (INIS)

    Sheared viscous flow deforms magnetic island and the formulation of the problem of control of neoclassical tearing modes by localized, phased electron cyclotron current drive (ECCD) may be altered. We address some aspects of this question by providing a new version of the Rutherford evolution model applicable to asymmetric neoclassical islands and concentrate on the estimate of the consequences of island deformation on the ECCD stabilization term.

  1. Effect of induced magnetic field on peristaltic flow of a micropolar fluid in an asymmetric channel

    OpenAIRE

    Shit, G. C.; Roy, M.; E. Y. K. Ng

    2010-01-01

    Of concern in this paper is an investigation of peristaltic transport of a physiological fluid in an asymmetric channel under long wave length and low-Reynolds number assumptions. The flow is assumed to be incompressible, viscous, electrically conducting micropolar fluid and the effect of induced magnetic field is taken into account. Exact analytical solutions obtained for the axial velocity, microrotation component, stream line pattern, magnetic force function, axial-induced magnetic field a...

  2. Asymmetric and Unsteady Flow Separation in High Mach Number Planar Nozzles

    OpenAIRE

    E. Shimshi; Ben-Dor, G.; Levy, A; A. Krothapalli

    2015-01-01

    This paper presents numerical and experimental findings regarding flow separation phenomenon in a high Mach number over expanded planar nozzle. The experimental work is done using a tapered nozzle with a variable area ratio that can produce separation Mach numbers in the range 2.6-3.5. Shadowgraph visualization reveals that depending on the nozzle pressure ratio and the area ratio, steady symmetric, unsteady symmetric and steady asymmetric separations can occur. These sepa...

  3. Peristaltic Flow of Phan-Thien-Tanner Fluid in an Asymmetric Channel with Porous Medium

    OpenAIRE

    Kuppalapalle Vajravelu; S.Sreenadh; Lakshminarayana, P; G. Sucharitha; Rashidi, M. M.

    2016-01-01

    This paper deals with peristaltic transport of Phan-Thien-Tanner fluid in an asymmetric channel induced by sinusoidal peristaltic waves traveling down the flexible walls of the channel. The flow is investigated in a wave frame of reference moving with the velocity of the waveby using the long wavelength and low Reynolds number approximations.The nonlinear governing equations are solved employing a perturbation method by choosing as the perturbation parameter. The expressions for velocity, s...

  4. Magnetohydrodynamic Fully Developed Combined Convection Flow between Vertical Plates Heated Asymmetrically

    International Nuclear Information System (INIS)

    Magnetohydrodynamic (MHD) fully developed flow of a viscous incompressible electrically conducting fluid in a vertical channel during combined convection, with asymmetric heating of the wall, under the influence of a constant pressure gradient and in the presence of an uniform transverse magnetic field, is studied. Exact solution of the governing equation is obtained in a closed form. The solution in a dimensionless form contains two pertinent flow parameters, viz. M (the Hartmann number) and Gr (the Grashof number). The limiting cases of a MHD forced and free convection are analysed, what has not been done earlier in the literature. The occurrence of flow reversal indicates that there arises a flow reversal at the cold wall when rT=1 while, for rT<1, no flow reversal is possible in the absence of magnetic forces. (author)

  5. Rarefaction effects on the flow characteristics in microchannels on asymmetric wall thermal condition

    Directory of Open Access Journals (Sweden)

    Md. Tajul Islam

    2015-01-01

    Full Text Available Rarefaction effects on the flow characteristics in 2D microchannels on asymmetric wall thermal conditions are investigated by control volume technique. In order to examine the influence of Knudsen numbers on the flow characteristics, a series of simulations for both compressible and incompressible flow with different Reynolds and Knudsen numbers are performed. Nitrogen gas is used as working fluid and the slip boundary conditions are used on the walls. The Navier-Stokes and energy equations are solved simultaneously. The results are found in good agreement with those predicted by analytical solutions in 2D continuous flow model employing first order slip boundary conditions. It is shown here that the Knudsen number has effects on velocity and temperature distribution for both the compressible and incompressible flows. It causes the velocity slip on the wall and causes the temperature difference between the wall temperature and the gas temperature on the wall.

  6. Evaluation of regional cerebral blood flow in patient with atypical senile dementia with asymmetrical calcification.

    Science.gov (United States)

    Shoyama, Masaru; Ukai, Satoshi; Shinosaki, Kazuhiro

    2015-12-01

    We report an 83-year-old woman with atypical senile dementia with Fahr-type calcification. Brain computed tomography demonstrated asymmetrical calcification predominant in the basal ganglia on the right side and pronounced diffuse cortical atrophy in the frontotemporal areas. The patient was clinically diagnosed with diffuse neurofibrillary tangles with calcification. Brain single photon emission computed tomography findings revealed that cerebral blood flow was reduced on the right side, as compared with the left side, in widespread areas. Hemispheric asymmetry in both calcification and cerebral blood flow suggests a relationship between calcification and vascular changes. PMID:25737312

  7. LATTICE BGK MODEL SIMULATION OF ASYMMETRIC FLOW INSIDE A CONTINUOUS SLAB CASTING MOLD

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xiao-jun; SHEN Hou-fa

    2006-01-01

    The incompressible lattice Bhatnager-Gross-Krook (BGK) model of computational fluid dynamics, from which the unsteady incompressible Navier-Stokes equations can be exactly derived with the limit of small Mach number, was established in continuous casting mold. An asymmetric flow pattern in the two-dimensional central plane of continuous slab casting mold was simulated, and the flow pattern is not stationary but changes over frequently if the Reynolds number is larger than 3000 or so. The results are found to be in excellent agreement with previous experimental results.

  8. Magnetohydrodynamic peristaltic flow of a hyperbolic tangent fluid in a vertical asymmetric channel with heat transfer

    Institute of Scientific and Technical Information of China (English)

    Sohail Nadeem; Safia Akram

    2011-01-01

    In the present paper we discuss the magnetohydrodynamic (MHD) peristaltic flow of a hyperbolic tangent fluid model in a vertical asymmetric channel under a zero Reynolds number and long wavelength approximation. Exact solution of the temperature equation in the absence of dissipation term has been computed and the analytical expression for stream function and axial pressure gradient are established. The flow is analyzed in a wave frame of reference moving with the velocity of wave. The expression for pressure rise has been computed numerically. The physical features of pertinent parameters are analyzed by plotting graphs and discussed in detail.

  9. Asymmetric flows over symmetric surfaces: capacitive coupling in induced-charge electro-osmosis

    International Nuclear Information System (INIS)

    We report curious asymmetric induced-charge electro-osmotic (ICEO) flows over a symmetric, planar gate electrode under applied ac electric fields, whereas symmetric, counter-rotating rolls are expected. Furthermore, the asymmetric component of the flow is consistently directed towards the grounded electrode. We propose that capacitive coupling of the gate electrode to the microscope stage-a comparatively large equipotential surface that acts effectively as a ground-is responsible for this symmetry breaking. This stray capacitance drives the formation of a double layer whose zeta potential is proportional to the potential drop from the electrolyte directly above the gate electrode to the external stage. Therefore, the charge in this 'stray' double layer varies in phase with the driving field, resulting in a rectified, steady flow as with standard ICEO. We experimentally vary the stray capacitance, the electric potential of the stage and the location of the gate electrode, and find that the effect on the stray flow is qualitatively consistent with the predictions of the proposed mechanism. In the process, we demonstrate that capacitive coupling offers an additional means of manipulating fluid flow over a polarizable surface.

  10. Investigation on pipe-wall thinning by flow accelerated corrosion. Occurrence of asymmetrical flow by combined effect of swirling flow and orifice bias

    International Nuclear Information System (INIS)

    The flow accelerated corrosion in a pipe is an important topic of interest associated with pipe-wall thinning phenomenon in a highly aged nuclear power plant. In the present study, the velocity field behind an orifice in a pipe is studied by PIV measurement in some combinations of swirl flow magnitudes and orifice bias. The flow observations along the flow axis and across the pipe indicate that the effect of orifice bias is not so influential on the flow behavior behind the orifice at small swirl flow magnitude. However, the asymmetrical flow pattern is observed in the flow behind the orifice at large swirl flow magnitude. The accelerated flow behind the orifice reattaches on the pipe wall of shorter orifice height and the corresponding velocity fluctuation decreases at large swirl flow magnitude, which occurs even at the small orifice bias of 0.7% of pipe diameter. This phenomenon is expected to promote the asymmetrical distribution of pipe-wall thickness due to flow accelerated corrosion in a prototype pipe flow. (author)

  11. The mechanism of asymmetric pipe-wall thinning behind an orifice by combined effect of swirling flow and orifice bias

    International Nuclear Information System (INIS)

    Highlights: ► The mechanism of asymmetric pipe-wall thinning is clarified. ► Flow fields and pipe-wall thinning are evaluated experimentally for orifice flow. ► We demonstrate combined effects of swirling flows and orifice biases on flows. ► Strong swirling flows and orifice biases cause an asymmetric pipe-wall thinning. - Abstract: In this paper, the mechanism of asymmetric pipe-wall thinning caused by flow accelerated corrosion behind an orifice in a circular pipe is studied by measuring the velocity fields by PIV and the mass transfer coefficients by naphthalene sublimation method. An attention is placed on the variations of the velocity fields and mass flux under the combined effect of swirling flow and orifice bias. The present measurement indicates that the flow field become asymmetric about the pipe axis due to the influence of swirling flow at large swirl intensity S = 0.3 in combination with an allowable orifice bias as small as 0.8% of a pipe diameter of standard steel pipes. This flow phenomenon results in the asymmetric distribution of mass transfer coefficient along the pipe-wall behind the orifice. The position of enhanced mass transfer occurs on the shorter orifice side near the orifice due to the flow reattachment, while the flow on the longer orifice side remains the same distribution of mass transfer coefficient as the case without swirl. These variations of velocity field and mass transfer data suggest that the mechanism of asymmetric pipe-wall thinning behind the orifice is due to the combined effect of swirling flow and orifice bias.

  12. A Numerical Simulation of Cell Separation by Simplified Asymmetric Pinched Flow Fractionation.

    Science.gov (United States)

    Ma, Jing-Tao; Xu, Yuan-Qing; Tang, Xiao-Ying

    2016-01-01

    As a typical microfluidic cell sorting technique, the size-dependent cell sorting has attracted much interest in recent years. In this paper, a size-dependent cell sorting scheme is presented based on a controllable asymmetric pinched flow by employing an immersed boundary-lattice Boltzmann method (IB-LBM). The geometry of channels consists of 2 upstream branches, 1 transitional channel, and 4 downstream branches (D-branches). Simulations are conducted by varying inlet flow ratio, the cell size, and the ratio of flux of outlet 4 to the total flux. It is found that, after being randomly released in one upstream branch, the cells are aligned in a line close to one sidewall of the transitional channel due to the hydrodynamic forces of the asymmetric pinched flow. Cells with different sizes can be fed into different downstream D-branches just by regulating the flux of one D-branch. A principle governing D-branch choice of a cell is obtained, with which a series of numerical cases are performed to sort the cell mixture involving two, three, or four classes of diameters. Results show that, for each case, an adaptive regulating flux can be determined to sort the cell mixture effectively. PMID:27597877

  13. Influence of convective conditions in radiative peristaltic flow of pseudoplastic nanofluid in a tapered asymmetric channel

    Science.gov (United States)

    Hayat, T.; Iqbal, Rija; Tanveer, Anum; Alsaedi, A.

    2016-06-01

    This paper looks at the influences of magnetohydrodynamics (MHD) and thermal radiation on peristaltic transport of a pseudoplastic nanofluid in a tapered asymmetric channel. The tapered channel walls satisfy convective boundary conditions. The governing equations for the balance of mass, momentum, temperature and volume fraction for pseudoplastic nanofluid are first formulated and then utilized for long wavelength and small Reynolds number considerations. Effects of involved parameters on the flow characteristics have been plotted and examined. It is observed that the heat transfer Biot number shows a dual behavior on the temperature of nanofluid particles whereas the mass transfer Biot number with its increasing values enhances the fluid temperature.

  14. Peristaltic flow in an asymmetric channel with convective boundary conditions and Joule heating

    Institute of Scientific and Technical Information of China (English)

    Abbasi Fahad Munir; Hayat Tasawar; Ahmad Bashir

    2014-01-01

    The peristaltic transport of viscous fluid in an asymmetric channel is concentrated. The channel walls exhibit convective boundary conditions. Both cases of hydrodynamic and magnetohydrodynamic (MHD) fluids are considered. Mathematical analysis has been presented in a wave frame of reference. The resulting problems are non-dimensionalized. Long wavelength and low Reynolds number approximations are employed. Joule heating effect on the thermal equation is retained. Analytic solutions for stream function and temperature are constructed. Numerical integration is carried out for pressure rise per wavelength. Effects of influential flow parameters have been pointed out through graphs.

  15. Application of advanced turbulence models for turbulent flow in a plane asymmetric diffuser

    Czech Academy of Sciences Publication Activity Database

    Příhoda, Jaromír; Sedlář, M.

    Žilina : EDIS Žilina, 2010, s. 249-254. ISBN 978-80-554-0189-8. [Aplikácia experimentálnych a numerických metód v mechanike tekutín a energetike. Bojnice (SK), 28.04.2010-30.04.2010] R&D Projects: GA ČR GA103/09/0977 Institutional research plan: CEZ:AV0Z20760514 Keywords : plane asymmetric diffuser * modelling of separated flow Subject RIV: BK - Fluid Dynamics

  16. Mechanism and kinetics of the loss of poorly soluble drugs from liposomal carriers studied by a novel flow field-flow fractionation-based drug release-/transfer-assay.

    Science.gov (United States)

    Hinna, Askell Hvid; Hupfeld, Stefan; Kuntsche, Judith; Bauer-Brandl, Annette; Brandl, Martin

    2016-06-28

    Liposomes represent a versatile drug formulation approach e.g. for improving the water-solubility of poorly soluble drugs but also to achieve drug targeting and controlled release. For the latter applications it is essential that the drug remains associated with the liposomal carrier during transit in the vascular bed. A range of in vitro test methods has been suggested over the years for prediction of the release of drug from liposomal carriers. The majority of these fail to give a realistic prediction for poorly water-soluble drugs due to the intrinsic tendency of such compounds to remain associated with liposome bilayers even upon extensive dilution. Upon i.v. injection, in contrast, rapid drug loss often occurs due to drug transfer from the liposomal carriers to endogenous lipophilic sinks such as lipoproteins, plasma proteins or membranes of red blood cells and endothelial cells. Here we report on the application of a recently introduced in vitro predictive drug transfer assay based on incubation of the liposomal drug carrier with large multilamellar liposomes, the latter serving as a biomimetic model sink, using flow field-flow fractionation as a tool to separate the two types of liposomes. By quantifying the amount of drug remaining associated with the liposomal drug carrier as well as that transferred to the acceptor liposomes at distinct times of incubation, both the kinetics of drug transfer and release to the water phase could be established for the model drug p-THPP (5,10,15,20-tetrakis(4-hydroxyphenyl)21H,23H-porphine). p-THPP is structurally similar to temoporfin, a photosensitizer which is under clinical evaluation in a liposomal formulation. Mechanistic insights were gained by varying the donor-to-acceptor lipid mass ratio, size and lamellarity of the liposomes. Drug transfer kinetics from one liposome to another was found rate determining as compared to redistribution from the outermost to the inner concentric bilayers, such that the overall

  17. Predictions of buoyancy-induced flow in asymmetrical heated rotating cavity system

    International Nuclear Information System (INIS)

    This paper presents the finite difference solutions for buoyancy-induced flow in the asymmetrical heated rotating cavity system for the range of rotational Reynolds numbers Re =6.13x10/sup 5/< Re/sub theta/=4.4*10/sup 6/ and the mass flow rates C/sub w/ <28000< C/sub w/ <3000. All the simulations have been carried out through the CFD (computational Fluid Dynamics) commercial code, ANSYS Fluent 12.0, by adopting axisymmetric, steady-state and elliptic technique. Two well know models namely k-epsilon and the Reynolds stress models have been employed. The simulated results illustrate the important aspects of the heated rotating cavity flow system. The noteworthy influence of buoyancy-induced flow have been observed on the predicted stream line, static temperature contours and the local Nusselt numbers for the rotating cavity flow system. The noteworthy influence of buoyancy-induced flow have been observed on the predicted stream lines, static temperature contours and the local Nusselt numbers for the rotating cavity space. A comparison of the predicted local nusselt numbers for the hot and cold discs showed a good level of agreement with the measurement. (author)

  18. Theoretical analysis of electrokinetic flow and heat transfer in a microchannel under asymmetric boundary conditions.

    Science.gov (United States)

    Soong, C Y; Wang, S H

    2003-09-01

    The main theme of the present work is to investigate the electrokinetic effects on liquid flow and heat transfer in a flat microchannel of two parallel plates under asymmetric boundary conditions including wall-sliding motion, unequal zeta potentials, and unequal heat fluxes on two walls. Based on the Debye-Huckel approximation, an electrical potential solution to the linearized Poisson-Boltzmann equation is obtained and employed in the analysis. The analytic solutions of the electrical potential, velocity distributions, streaming potential, friction coefficient, temperature distribution, and heat transfer rate are obtained, and thereby the effects of electrokinetic separation distance (K), zeta-potential level (zeta;(1)), ratio of two zeta potentials (r(zeta) identical with zeta;(2)/zeta;(1)), wall-sliding velocity (u(w)), and heat flux ratio (r(q) identical with q"(2)/q"(1)) are investigated. The present results reveal the effects of wall-sliding and zeta-potential ratio on the hydrodynamic nature of microchannel flow, and they are used to provide physical interpretations for the resultant electrokinetic effects and the underlying electro-hydrodynamic interaction mechanisms. In the final part the results of potential and velocity fields are applied in solving the energy equation. The temperature distributions and heat transfer characteristics under the asymmetrical kinematic, electric, and thermal boundary conditions considered presently are dealt with. PMID:12927184

  19. Effect of induced magnetic field on peristaltic flow of a micropolar fluid in an asymmetric channel

    CERN Document Server

    Shit, G C; Ng, E Y K; 10.1002/cnm.1397

    2010-01-01

    Of concern in this paper is an investigation of peristaltic transport of a physiological fluid in an asymmetric channel under long wave length and low-Reynolds number assumptions. The flow is assumed to be incompressible, viscous, electrically conducting micropolar fluid and the effect of induced magnetic field is taken into account. Exact analytical solutions obtained for the axial velocity, microrotation component, stream line pattern, magnetic force function, axial-induced magnetic field as well as the current density distribution across the channel. The flow phenomena for the pumping characteristics, trapping and reflux are also investigated. The results presented reveal that the velocity decreases with the increase of magnetic field as well as the coupling parameter. Moreover, the trapping fluid can be eliminated by the application of an external magnetic field. Thus, the study bears the promise of important applications in physiological systems.

  20. Abundance, size distributions and trace-element binding of organic and iron-rich nanocolloids in Alaskan rivers, as revealed by field-flow fractionation and ICP-MS

    Science.gov (United States)

    Stolpe, Björn; Guo, Laodong; Shiller, Alan M.; Aiken, George R.

    2013-03-01

    Water samples were collected from six small rivers in the Yukon River basin in central Alaska to examine the role of colloids and organic matter in the transport of trace elements in Northern high latitude watersheds influenced by permafrost. Concentrations of dissolved organic carbon (DOC), selected elements (Al, Si, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Rb, Sr, Ba, Pb, U), and UV-absorbance spectra were measured in 0.45 μm filtered samples. 'Nanocolloidal size distributions' (0.5-40 nm, hydrodynamic diameter) of humic-type and chromophoric dissolved organic matter (CDOM), Cr, Mn, Fe, Co, Ni, Cu, Zn, and Pb were determined by on-line coupling of flow field-flow fractionation (FFF) to detectors including UV-absorbance, fluorescence, and ICP-MS. Total dissolved and nanocolloidal concentrations of the elements varied considerably between the rivers and between spring flood and late summer base flow. Data on specific UV-absorbance (SUVA), spectral slopes, and the nanocolloidal fraction of the UV-absorbance indicated a decrease in aromaticity and size of CDOM from spring flood to late summer. The nanocolloidal size distributions indicated the presence of different 'components' of nanocolloids. 'Fulvic-rich nanocolloids' had a hydrodynamic diameter of 0.5-3 nm throughout the sampling season; 'organic/iron-rich nanocolloids' occurred in the stability constant of the metal (+II)-organic complexes, while stronger association of Cr to the iron-rich nanocolloids was attributed to the higher oxidation states of Cr (+III or +IV). Changes in total dissolved element concentrations, size and composition of CDOM, and occurrence and size of organic/iron and iron-rich nanocolloids were related to variations in their sources from either the upper organic-rich soil or the deeper mineral layer, depending on seasonal variations in hydrological flow patterns and permafrost dynamics.

  1. Particle-in-cell simulation study of the scaling of asymmetric magnetic reconnection with in-plane flow shear

    Science.gov (United States)

    Doss, C. E.; Cassak, P. A.; Swisdak, M.

    2016-08-01

    We investigate magnetic reconnection in systems simultaneously containing asymmetric (anti-parallel) magnetic fields, asymmetric plasma densities and temperatures, and arbitrary in-plane bulk flow of plasma in the upstream regions. Such configurations are common in the high-latitudes of Earth's magnetopause and in tokamaks. We investigate the convection speed of the X-line, the scaling of the reconnection rate, and the condition for which the flow suppresses reconnection as a function of upstream flow speeds. We use two-dimensional particle-in-cell simulations to capture the mixing of plasma in the outflow regions better than is possible in fluid modeling. We perform simulations with asymmetric magnetic fields, simulations with asymmetric densities, and simulations with magnetopause-like parameters where both are asymmetric. For flow speeds below the predicted cutoff velocity, we find good scaling agreement with the theory presented in Doss et al. [J. Geophys. Res. 120, 7748 (2015)]. Applications to planetary magnetospheres, tokamaks, and the solar wind are discussed.

  2. A physical model of asymmetric vortices flow structure in regular state over slender body at high angle of attack

    Institute of Scientific and Technical Information of China (English)

    邓学蓥; 王刚; 陈学锐; 王延奎; 刘沛清; 郗忠祥

    2003-01-01

    In subcritical Reyolds number flow region, the repeatable and determinate asymmetric vortices flow at regular state can be obtained by manually setting mini-perturbation on the nose of a pointed ogive-cylinder model at high angle of attack and zero side slip. Test results of this study involve surface pressure distributions, sectional-side-force distributions and flow visualizations. The analyses of these results revealed a complicated multi-vortices system at regular state in which asymmetric twin vortices with inception region and fully developed region, asymmetric triple vortices, four vortices region, five vortices region and Karman-vortex-street-like flow region are developed along the slender body. The correlation between multi-vortices system structures and corresponding sectional-side-force distribution is given. The behaviors of multi-vortices flow structure at the peculiar points of sectional-side-force distributions and characteristics of corresponding pressure distribution are analysed. Finally, a physical model of asymmetric multi-vortices flow structure in regular state over slender body is developed.

  3. An econometric essay for the asymmetric volatility content of the portfolio flows: EGARCH evidence from the Turkish economy

    OpenAIRE

    Korap, Levent

    2010-01-01

    In this paper, the information content of the volatility observed on portfolio flows is tried to be econometrically examined for the Turkish economy. Our findings employing EGARCH estimation methodology reveal that the volatility shocks on the portfolio flows seem to be of a quite persistent form and that the news impact extracted from the model is asymmetric such that the conditional variance of the net portfolio flows reacts more to past negative shocks than to positive innovations of the e...

  4. Buoyancy Effects on Unsteady MHD Flow of a Reactive Third-Grade Fluid with Asymmetric Convective Cooling

    Directory of Open Access Journals (Sweden)

    Tirivanhu Chinyoka

    2015-01-01

    Full Text Available This article examines the combined effects of buoyancy force and asymmetrical convective cooling on unsteady MHD channel flow and heat transfer characteristics of an incompressible, reactive, variable viscosity and electrically conducting third grade fluid. The chemical kinetics in the flow system is exothermic and the asymmetric convective heat transfers at the channel walls follow the Newton’s law of cooling. The coupled nonlinear partial differential equations governing the problem are derived and solved numerically using a semi-implicit finite difference scheme. Graphical results are presented and physical aspects of the problem are discussed with respect to various parameters embedded in the system.

  5. Plasma flow reversals at the dayside magnetopause and the origin of the asymmetric polar cap convection

    International Nuclear Information System (INIS)

    A number of events have been observed in the Los Alamos/Garching fast plasma experiment data from ISEE 2 within ± 3 hours of noon wherein the y component of the plasmas flow within the low latitude boundary layer and magnetopause current layer is oppositely directed to that in the adjacent magnetosheath. When the y component, By, of the local magnetosheath magnetic field is positive, events of this nature are found preferentially in the northern dusk and southern dawn quadrants, and when By is negative, they are found preferentially in the opposite two quadrants. Plasma flows in these events are always also poleward, that is they are always directed away from the GSE equatorial plane. The observations are qualitatively and quantitatively consistent with previous observations of accelerated flows at the magnetopause and with models of magnetic reconnection, with the reconnection occurring at low latitudes near the GSE XY plane independent of the magnitude or the sign of the y component of the local magnetosheath magnetic field. Local magnetic shears at the magnetopause for these events range from 60 to 180 degs, which, together with the occurrence of these events at low latitudes, does not tend to support the antiparallel merging hypothesis. These observations of By-dependent flow reversals provide a graphic demonstration of how asymmetric polar cap convection and related phenomena, such as the Svalgaard-Mansurov effect, originate in magnetic reconnection at the dayside magnetopause

  6. Predictions of Buoyancy-induced Flow in Asymmetrical Heated Rotating Cavity System

    Directory of Open Access Journals (Sweden)

    Abdul Fatah Abbassi

    2013-04-01

    Full Text Available This paper presents the finite difference solutions for buoyancy-induced flow in the asymmetrical heated rotating cavity system for the range of rotational Reynolds numbers Reθ =6.13x10^5 flow rates Cw<28000flow system. The noteworthy influence of buoyancy-induced flow have been observed on the predicted stream lines, static temperature contours and the local Nusselt numbers for the rotating cavity space. A comparison of the predicted local Nusselt numbers for the hot and cold discs showed a good level of agreement with the measurements.

  7. An investigation of jet trajectory in flow through scaled vocal fold models with asymmetric glottal passages

    Science.gov (United States)

    Erath, Byron D.; Plesniak, Michael W.

    2006-11-01

    Pulsatile two-dimensional flow through asymmetric static divergent models of the human vocal folds is investigated. Included glottal divergence angles are varied between 10° and 30°, with asymmetry angles between the vocal fold pairs ranging from 5° to 15°. The model glottal configurations represent asymmetries that arise during a phonatory cycle due to voice disorders. The flow is scaled to physiological values of Reynolds, Strouhal, and Euler numbers. Data are acquired in the anterior posterior mid-plane of the vocal fold models using phase-averaged Particle Image Velocimetry (PIV) acquired at ten discrete locations in a phonatory cycle. Glottal jet stability arising from the vocal fold asymmetries is investigated and compared to previously reported work for symmetric vocal fold passages. Jet stability is enhanced with an increase in the included divergence angle, and the glottal asymmetry. Concurrently, the bi-modal jet trajectory and flow unsteadiness diminishes. Consistent with previous findings, the flow attachment due to the Coanda effect occurs when the acceleration of the forcing function is zero.

  8. Effect of surface radiation on natural convective flows and onset of flow reversal in asymmetrically heated vertical channels

    International Nuclear Information System (INIS)

    Numerical solutions on the influence of surface radiation on the laminar air flow induced by natural convection in vertical, asymmetrically-heated channels are discussed. Variable property effects are accounted for in a full-elliptic mathematical formulation. The density variation is determined from the state equation for ideal gas. The experimental design and data reported in Webb and Hill [1] are taken as the base cases for carrying out the computations. The occurrence of flow reversals is first considered and revisited for pure natural convection, and the Nusselt number correlations derived from the numerical results are favorably compared with those reported in [1]. It is shown that the general effect of surface radiation is to delete the onset of pocket-like re-circulations at the top part of the channel, to reduce the heated wall temperatures, and to increase the facing wall temperatures. Comparisons with usual methods used for decoupling the surface radiation effects are discussed. In the range of parameters investigated, increases in differences between inlet and maximum wall temperatures up to 200 K are shown to have small influences on the flow field and negligible effects on heat transfer performances. (authors)

  9. Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetric Flow Control-Part I: Non-Axisymmetrical Flow in Centrifugal Compressor.

    Science.gov (United States)

    Yang, Mingyang; Zheng, Xinqian; Zhang, Yangjun; Bamba, Takahiro; Tamaki, Hideaki; Huenteler, Joern; Li, Zhigang

    2013-03-01

    This is Part I of a two-part paper documenting the development of a novel asymmetric flow control method to improve the stability of a high-pressure-ratio turbocharger centrifugal compressor. Part I focuses on the nonaxisymmetrical flow in a centrifugal compressor induced by the nonaxisymmetrical geometry of the volute while Part II describes the development of an asymmetric flow control method to avoid the stall on the basis of the characteristic of nonaxisymmetrical flow. To understand the asymmetries, experimental measurements and corresponding numerical simulation were carried out. The static pressure was measured by probes at different circumferential and stream-wise positions to gain insights about the asymmetries. The experimental results show that there is an evident nonaxisymmetrical flow pattern throughout the compressor due to the asymmetric geometry of the overhung volute. The static pressure field in the diffuser is distorted at approximately 90 deg in the rotational direction of the volute tongue throughout the diffuser. The magnitude of this distortion slightly varies with the rotational speed. The magnitude of the static pressure distortion in the impeller is a function of the rotational speed. There is a significant phase shift between the static pressure distributions at the leading edge of the splitter blades and the impeller outlet. The numerical steady state simulation neglects the aforementioned unsteady effects found in the experiments and cannot predict the phase shift, however, a detailed asymmetric flow field structure is obviously obtained. PMID:24891757

  10. Mixed Convection Flow and Heat Transfer of Micropolar Fluid in a Vertical Channel with Symmetric and Asymmetric Wall Heating Conditions

    OpenAIRE

    Patil Mallikarjun B; Chandrali Baishya

    2016-01-01

    Analytical solutions for fully developed mixed convection flow of a micro polar fluid with heat generation or heat absorption in a parallel plate vertical channel with symmetric and asymmetric wall temperature distribution has been presented. The two boundaries of the channel are kept either at equal or at different temperatures as isothermal-isothermal, isoflux-isothermal and isothermal-isoflux cases. Reverse flow conditions are observed with increase in micro vortex viscosity. M...

  11. Analytical Model of an Asymmetric Sunspot with a Steady Plasma Flow in its Penumbra

    Science.gov (United States)

    Solov'ev, A. A.; Kirichek, E. A.

    2016-08-01

    A new exact analytical solution to the stationary problem of ideal magnetohydrodynamics is derived for an unipolar asymmetric sunspot immersed in a realistic solar atmosphere. The radial and vertical profiles of pressure, plasma density, and temperature in the visible layers of the sunspot are calculated. The reduction in plasma density in the magnetic funnel of the sunspot, corresponding to the Wilson depression, is also obtained. The magnetic structure of the sunspot is given analytically in a realistic way: a part of the magnetic flux of the sunspot approaches the surrounding photosphere at the outer edge of the penumbra. The magnetic field of the sunspot is not assumed to be axially symmetric. For the first time, the angular dependence of the physical variables in this model allows us to simulate not only a deviation from the circular shape of the sunspot, but also a fine filamentary structure of the sunspot penumbra. The Alfvén Mach number (the ratio of the plasma speed to the Alfvén speed) is zero at the center of the sunspot and rises slowly toward the periphery of the sunspot; this corresponds to the structure of the Evershed flow in the penumbra. The Evershed flow in our model is mainly concentrated in dark penumbral filaments, as is observed.

  12. Analytical Model of an Asymmetric Sunspot with a Steady Plasma Flow in its Penumbra

    Science.gov (United States)

    Solov'ev, A. A.; Kirichek, E. A.

    2016-06-01

    A new exact analytical solution to the stationary problem of ideal magnetohydrodynamics is derived for an unipolar asymmetric sunspot immersed in a realistic solar atmosphere. The radial and vertical profiles of pressure, plasma density, and temperature in the visible layers of the sunspot are calculated. The reduction in plasma density in the magnetic funnel of the sunspot, corresponding to the Wilson depression, is also obtained. The magnetic structure of the sunspot is given analytically in a realistic way: a part of the magnetic flux of the sunspot approaches the surrounding photosphere at the outer edge of the penumbra. The magnetic field of the sunspot is not assumed to be axially symmetric. For the first time, the angular dependence of the physical variables in this model allows us to simulate not only a deviation from the circular shape of the sunspot, but also a fine filamentary structure of the sunspot penumbra. The Alfvén Mach number (the ratio of the plasma speed to the Alfvén speed) is zero at the center of the sunspot and rises slowly toward the periphery of the sunspot; this corresponds to the structure of the Evershed flow in the penumbra. The Evershed flow in our model is mainly concentrated in dark penumbral filaments, as is observed.

  13. Design, x-ray image guidance and flow characterization of new asymmetric vascular stents

    Science.gov (United States)

    Ionita, Ciprian N.

    Recent advances of x-ray imaging techniques have made possible improvement and development of new minimally invasive image guided interventions (IGI). Capabilities such as real-time, high special resolution image guidance with down to sub-millimeter precision, enabled a large increase in the number of the new minimally invasive treatments using x-ray guidance. One such treatment is a new method we are developing to treat intracranial aneurysms (ICA) using a new device, the asymmetric vascular stent (AVS). The present work deals with the physical aspects of the development and evaluation of this new device. In general, stents are specially designed vascular prosthesis similar to a uniform porous wire cylinder. Unlike current stents, the new devices have a low porous region which creates an asymmetry, hence the name we use for the device. The treatment of an intracranial aneurysm using AVSs is done by placing the low porous part over the aneurysm neck. By doing so, the flow in the aneurysm is modified and conditions for the thrombosis are created. The research on the device consisted of three parts: (i) design and fabrication of the device, (ii) flow evaluation and (iii) accurate of localization of the device during x-ray IGI. The first part involved the process design and fabrication of the stents using laser micro-welding. The second part was dedicated to flow evaluation and flow characterization of the AVS. The characterization of the flow parameters of the stent were done based on physical aspects of the flow and the structure geometry. Theoretical or empirical models were evaluated experimentally in order to verify if they were appropriate for our device. We verified the effects that stents have on flow in aneurysms using methods such as Particle Image Velocimetry (PIV) and x-ray video-densitometric measurements. The last part involved the development of a marking technique using x-ray radio-opaque markers. We verified the accuracy of placement of the stent when

  14. Viscoelasticity and nonlinear simple shear flow behavior of an entangled asymmetric exact comb polymer solution

    KAUST Repository

    Snijkers, F.

    2016-03-31

    We report upon the characterization of the steady-state shear stresses and first normal stress differences as a function of shear rate using mechanical rheometry (both with a standard cone and plate and with a cone partitioned plate) and optical rheometry (with a flow-birefringence setup) of an entangled solution of asymmetric exact combs. The combs are polybutadienes (1,4-addition) consisting of an H-skeleton with an additional off-center branch on the backbone. We chose to investigate a solution in order to obtain reliable nonlinear shear data in overlapping dynamic regions with the two different techniques. The transient measurements obtained by cone partitioned plate indicated the appearance of overshoots in both the shear stress and the first normal stress difference during start-up shear flow. Interestingly, the overshoots in the start-up normal stress difference started to occur only at rates above the inverse stretch time of the backbone, when the stretch time of the backbone was estimated in analogy with linear chains including the effects of dynamic dilution of the branches but neglecting the effects of branch point friction, in excellent agreement with the situation for linear polymers. Flow-birefringence measurements were performed in a Couette geometry, and the extracted steady-state shear and first normal stress differences were found to agree well with the mechanical data, but were limited to relatively low rates below the inverse stretch time of the backbone. Finally, the steady-state properties were found to be in good agreement with model predictions based on a nonlinear multimode tube model developed for linear polymers when the branches are treated as solvent.

  15. Identification of performance limiting electrode using asymmetric cell configuration in vanadium redox flow batteries

    Science.gov (United States)

    Agar, Ertan; Dennison, C. R.; Knehr, K. W.; Kumbur, E. C.

    2013-03-01

    In this study, the performance of a vanadium redox flow battery (VRFB) is investigated using asymmetric electrode configurations with raw and functionalized (i.e., acid-treated and heat-treated) electrodes. The use of heat-treated electrodes in both half-cells is chosen as the baseline case for comparison, as this configuration shows the best performance. When the positive electrode in the baseline case is replaced with a raw or acid-treated electrode, the voltage efficiency is found to be comparable to that of the baseline case. However, in the case where the negative electrode in the baseline case is replaced with a raw or acid-treated electrode, a significantly lower efficiency is observed, suggesting that the negative half-cell reactions limit the performance of a VRFB. To further investigate this observation, an additional analysis is performed using cyclic voltammetry. The reaction kinetics data suggests that the poor performance of the negative half-cell is not due to the slow kinetics, but rather stems from the fact that the reduction reaction in the negative half-cell occurs at a potential that is very close to the onset of hydrogen evolution. The formation of hydrogen gas bubbles blocks the reaction sites and suppresses the favorable effects of functionalization in the negative half-cell.

  16. Electrospun carbon nanofibers/electrocatalyst hybrids as asymmetric electrodes for vanadium redox flow battery

    Science.gov (United States)

    Wei, Guanjie; Fan, Xinzhuang; Liu, Jianguo; Yan, Chuanwei

    2015-05-01

    To improve the electrochemical activity of polyacrylonitrile (PAN)-based electrospun carbon nanofibers (ECNFs) toward vanadium redox couples, the multi-wall carbon nanotubes (CNTs) and Bi-based compound as electrocatalyst have been embedded in the ECNFs to make composite electrode, respectively. The morphology and electrochemical properties of pristine ECNFs, CNTs/ECNFs and Bi/ECNFs have been characterized. Among the three kinds of electrodes, the CNTs/ECNFs show best electrochemical activity toward VO2+/VO2+ redox couple, while the Bi/ECNFs present the best electrochemical activity toward V2+/V3+ redox couple. Furthermore, the high overpotential of hydrogen evolution on Bi/ECNFs makes the side-reaction suppressed. Because of the large property difference between the two composite electrodes, the CNTs/ECNFs and Bi/ECNFs are designed to act as positive and negative electrode for vanadium redox flow battery (VRFB), respectively. It not only does improve the kinetics of two electrode reactions at the same time, but also reduce the kinetics difference between them. Due to the application of asymmetric electrodes, performance of the cell is improved greatly.

  17. Asymmetrical gene flow in a hybrid zone of Hawaiian Schiedea (Caryophyllaceae species with contrasting mating systems.

    Directory of Open Access Journals (Sweden)

    Lisa E Wallace

    Full Text Available Asymmetrical gene flow, which has frequently been documented in naturally occurring hybrid zones, can result from various genetic and demographic factors. Understanding these factors is important for determining the ecological conditions that permitted hybridization and the evolutionary potential inherent in hybrids. Here, we characterized morphological, nuclear, and chloroplast variation in a putative hybrid zone between Schiedea menziesii and S. salicaria, endemic Hawaiian species with contrasting breeding systems. Schiedea menziesii is hermaphroditic with moderate selfing; S. salicaria is gynodioecious and wind-pollinated, with partially selfing hermaphrodites and largely outcrossed females. We tested three hypotheses: 1 putative hybrids were derived from natural crosses between S. menziesii and S. salicaria, 2 gene flow via pollen is unidirectional from S. salicaria to S. menziesii and 3 in the hybrid zone, traits associated with wind pollination would be favored as a result of pollen-swamping by S. salicaria. Schiedea menziesii and S. salicaria have distinct morphologies and chloroplast genomes but are less differentiated at the nuclear loci. Hybrids are most similar to S. menziesii at chloroplast loci, exhibit nuclear allele frequencies in common with both parental species, and resemble S. salicaria in pollen production and pollen size, traits important to wind pollination. Additionally, unlike S. menziesii, the hybrid zone contains many females, suggesting that the nuclear gene responsible for male sterility in S. salicaria has been transferred to hybrid plants. Continued selection of nuclear genes in the hybrid zone may result in a population that resembles S. salicaria, but retains chloroplast lineage(s of S. menziesii.

  18. Spatial genetic structure and asymmetrical gene flow within the Pacific walrus

    Science.gov (United States)

    Sonsthagen, Sarah A.; Jay, Chadwick V.; Fischbach, Anthony S.; Sage, George K.; Talbot, Sandra L.

    2012-01-01

    Pacific walruses (Odobenus rosmarus divergens) occupying shelf waters of Pacific Arctic seas migrate during spring and summer from 3 breeding areas in the Bering Sea to form sexually segregated nonbreeding aggregations. We assessed genetic relationships among 2 putative breeding populations and 6 nonbreeding aggregations. Analyses of mitochondrial DNA (mtDNA) control region sequence data suggest that males are distinct among breeding populations (ΦST=0.051), and between the eastern Chukchi and other nonbreeding aggregations (ΦST=0.336–0.449). Nonbreeding female aggregations were genetically distinct across marker types (microsatellite FST=0.019; mtDNA ΦST=0.313), as was eastern Chukchi and all other nonbreeding aggregations (microsatellite FST=0.019–0.035; mtDNA ΦST=0.386–0.389). Gene flow estimates are asymmetrical from St. Lawrence Island into the southeastern Bering breeding population for both sexes. Partitioning of haplotype frequencies among breeding populations suggests that individuals exhibit some degree of philopatry, although weak. High levels of genetic differentiation among eastern Chukchi and all other nonbreeding aggregations, but considerably lower genetic differentiation between breeding populations, suggest that at least 1 genetically distinct breeding population remained unsampled. Limited genetic structure at microsatellite loci between assayed breeding areas can emerge from several processes, including male-mediated gene flow, or population admixture following a decrease in census size (i.e., due to commercial harvest during 1880–1950s) and subsequent recovery. Nevertheless, high levels of genetic diversity in the Pacific walrus, which withstood prolonged decreases in census numbers with little impact on neutral genetic diversity, may reflect resiliency in the face of past environmental challenges.

  19. The influence of flow inertia, buoyancy, wind, and flow unsteadiness on mixing at the asymmetrical confluence of two large rivers

    Science.gov (United States)

    Ramón, Cintia L.; Prats, Jordi; Rueda, Francisco J.

    2016-08-01

    The rates and patterns of mixing of two large rivers with large density differences at a strongly asymmetrical confluence in northern Spain are analyzed. We assess the factors controlling the site where the denser river plunges and the mixing rates between the rivers. In particular, we focus on the interaction between inertial and buoyancy forces, the effect of wind forcing, and the unsteady nature of the hydraulic forcing. The steady-state location of the plunge line is shown to be controlled by an inertia-buoyancy balance, which accounts for the relative magnitude of the buoyancy forcing associated with density differences between the confluent rivers, and the magnitudes of both the main-stream and the side-flow (tributary) inertia. The plunge line moves to upstream locations as the inertia of the tributary increases (for low tributary inertia) and/or the density contrast between the rivers increases. This has important consequences for river mixing since mixing rates increase as the plunging occurs at the confluence. The high mixing rates in this case occur as a result of a large mixing interface surface area and high diffusivities. As the plunging area moves upstream or downstream of the confluence, vertical diffusivities or the area of contact available for mixing decrease and constrain mixing rates. Wind forcing, depending on its velocity and direction, affects mixing rates through (1) altering the buoyancy-inertia equilibrium and so changing the location of the plunge line, (2) altering the pattern of secondary circulation within the confluence and/or (3) increasing shear at the confluence. Flow unsteadiness can lead to changes in the location of the plunge line through time and thus can strongly modify mixing rates at the confluence. The downstream movement of the plunge line is advection dominated, while its upstream movement seems to respond to a baroclinic response of the confluence.

  20. Calculation and measurement of a neutral air flow velocity impacting a high voltage capacitor with asymmetrical electrodes

    International Nuclear Information System (INIS)

    This paper deals with the effects surrounding phenomenon of a mechanical force generated on a high voltage asymmetrical capacitor (the so called Biefeld-Brown effect). A method to measure this force is described and a formula to calculate its value is also given. Based on this the authors derive a formula characterising the neutral air flow velocity impacting an asymmetrical capacitor connected to high voltage. This air flow under normal circumstances lessens the generated force. In the following part this velocity is measured using Particle Image Velocimetry measuring technique and the results of the theoretically calculated velocity and the experimentally measured value are compared. The authors found a good agreement between the results of both approaches

  1. Calculation and measurement of a neutral air flow velocity impacting a high voltage capacitor with asymmetrical electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Malík, M., E-mail: michal.malik@tul.cz; Primas, J.; Kopecký, V.; Svoboda, M. [Faculty of Mechatronics, Informatics and Interdisciplinary Studies, Technical University of Liberec, Liberec, 461 17 (Czech Republic)

    2014-01-15

    This paper deals with the effects surrounding phenomenon of a mechanical force generated on a high voltage asymmetrical capacitor (the so called Biefeld-Brown effect). A method to measure this force is described and a formula to calculate its value is also given. Based on this the authors derive a formula characterising the neutral air flow velocity impacting an asymmetrical capacitor connected to high voltage. This air flow under normal circumstances lessens the generated force. In the following part this velocity is measured using Particle Image Velocimetry measuring technique and the results of the theoretically calculated velocity and the experimentally measured value are compared. The authors found a good agreement between the results of both approaches.

  2. Calculation and measurement of a neutral air flow velocity impacting a high voltage capacitor with asymmetrical electrodes

    Directory of Open Access Journals (Sweden)

    M. Malík

    2014-01-01

    Full Text Available This paper deals with the effects surrounding phenomenon of a mechanical force generated on a high voltage asymmetrical capacitor (the so called Biefeld-Brown effect. A method to measure this force is described and a formula to calculate its value is also given. Based on this the authors derive a formula characterising the neutral air flow velocity impacting an asymmetrical capacitor connected to high voltage. This air flow under normal circumstances lessens the generated force. In the following part this velocity is measured using Particle Image Velocimetry measuring technique and the results of the theoretically calculated velocity and the experimentally measured value are compared. The authors found a good agreement between the results of both approaches.

  3. Simultaneous effects of Hall and convective conditions on peristaltic flow of couple-stress fluid in an inclined asymmetric channel

    Indian Academy of Sciences (India)

    T Hayat; Maryam Iqbal; Humaira Yasmin; Fuad E Alsaadi; Huijun Gao

    2015-07-01

    A mathematical model is developed to analyse the peristaltic flow of couple-stress fluid in an inclined asymmetric channel with convective conditions. Soret and Dufour and Hall effects are taken into account. Analysis has been carried out in a wave frame of reference. Expressions for velocity, pressure gradient, temperature and concentration are constructed. Pumping and trapping phenomena are examined. Impact of sundry parameters on the velocity, temperature and concentration is discussed.

  4. Mixed Convection Flow and Heat Transfer of Micropolar Fluid in a Vertical Channel with Symmetric and Asymmetric Wall Heating Conditions

    Directory of Open Access Journals (Sweden)

    Patil Mallikarjun B

    2016-01-01

    Full Text Available Analytical solutions for fully developed mixed convection flow of a micro polar fluid with heat generation or heat absorption in a parallel plate vertical channel with symmetric and asymmetric wall temperature distribution has been presented. The two boundaries of the channel are kept either at equal or at different temperatures as isothermal-isothermal, isoflux-isothermal and isothermal-isoflux cases. Reverse flow conditions are observed with increase in micro vortex viscosity. Micro polar fluids display reduction in heat transfer rate.

  5. Effects of nose bluntness, roughness, and surface perturbations on the asymmetric flow past slender bodies at large angles of attack

    Science.gov (United States)

    Moskovitz, Cary A.; Dejarnette, F. R.; Hall, Robert M.

    1989-01-01

    The effects of such geometric perturbations as variations of model-tip sharpness and roughness, as well as discrete surface perturbations, on the asymmetric flow past slender bodies is experimentally investigated for the cases of a cone/cylinder model having a 10-deg semiapex angle and a 3.0-caliber tangent ogive model. Both models have base diameters of 3.5 inches, and were tested in laminar flow conditions at angles-of-attack in the 30-60 deg range. Single, discrete roughness elements were represented by beads; bead effectiveness was judged on the basis of the extent to which they affected the flowfield in various conditions.

  6. Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetrical Flow Control—Part II: Nonaxisymmetrical Self-Recirculation Casing Treatment

    OpenAIRE

    Zheng, Xinqian; Zhang, Yangjun; Yang, Mingyang; Bamba, Takahiro; Tamaki, Hideaki

    2012-01-01

    This is part II of a two-part paper involving the development of an asymmetrical flow control method to widen the operating range of a turbocharger centrifugal compressor with high-pressure ratio. A nonaxisymmetrical self-recirculation casing treatment (SRCT) as an instance of asymmetrical flow control method is presented. Experimental and numerical methods were used to investigate the impact of nonaxisymmetrical SRCT on the surge point of the centrifugal compressor. First, the influence of t...

  7. Comparison of radial flow effects on partitions of multifragmenting sources formed in symmetric and asymmetric central collisions

    Directory of Open Access Journals (Sweden)

    Frankland J.D.

    2015-01-01

    Full Text Available The role of collective radial expansion in determining multifragmentation partition properties has previously been explored by comparing different-sized sources of the same excitation energy per nucleon formed by very different reaction mechanisms: excited quasi-projectiles from semi-peripheral Au+Au collisions and quasi-fused sources from central Xe+Sn collisions. New data has been obtained with INDRA on 181Ta+66Zn collisions in order to allow comparison of Xe+Sn data with quasi-fused systems having the same mass, charge and excitation energy per nucleon formed in mass-asymmetric reactions, for which a smaller initial compression is expected. Preliminary results confirm that, ceteris paribus, smaller radial flow leads to less fragments with more asymmetric partitions.

  8. The origin of asymmetric behavior of money flow in the business firm network

    Science.gov (United States)

    Miura, W.; Takayasu, H.; Takayasu, M.

    2012-09-01

    In the business firm network, the number of in-degrees and out-degrees show the same scale-free property, however, the distribution of authorities and hubs show asymmetric behavior. Here we show the result of an analysis of the two-link structure of the network to find the origin of this asymmetric behavior. We find the tendency for big construction firms intermediating small subcontracting firms to have higher hub degrees. By measuring the strength of preferential attachment rate of new companies, we also find a abnormally strong preferential attachment for which the exponent is 1.4 with respect to out-degree when a new company forms a business partnership with a construction company. We propose a new model that reproduces the asymmetric behavior of the degrees of authorities and hubs by changing the preferential attachment rate between the in-degree and the out-degree in the business firm network.

  9. Assessment of contrast flow modification in aneurysms treated with closed-cell self-deploying asymmetric vascular stents (SAVS)

    OpenAIRE

    Ionita, Ciprian N; Wang, Weiyuan; Bednarek, Daniel R.; Rudin, Stephen

    2010-01-01

    The Asymmetric Vascular Stent (AVS) for intracranial aneurysm (IA) treatment is an experimental device, specially designed for intra-aneurysmal blood flow diversion and thrombosis promotion. The stent has a low-porous patch to cover only the aneurysm neck while the rest of the stent is very porous to avoid blockage of adjacent branches. The latest AVS design is similar to state-of-art, closed-cell, self-expanding, neurovascular stent. The stents were used to treat sixteen rabbit-elastase aneu...

  10. Perturbation method of analyzing mode localization of asymmetrical plate-type structure in incompressible flows

    International Nuclear Information System (INIS)

    The dynamical characteristics of a simple two-span parallel flat plate-type model vibrating in incompressible water are studied here. The assumption mode method is used to form the motion equation of the structure. By using a second order perturbation method, the great emphasis is focused on the influences of the asymmetrical parameter of the structure, the deviation of length and stiffness of the torsional spring on the degrees of mode localization of the structure. The results show that the second method can be applied to predict the dynamical characteristics of the structure accurately. The influences of the coupling effect of the fluid on the phenomena of the two piece beams' mode localization are different. The asymmetrical parameter of length is the main factor that leads to the behaviors of mode localization of the structure. The deviation of stiffness of the torsional spring, too, has significant influences on the phenomena of mode localization

  11. Inertial focusing in a straight channel with asymmetrical expansion–contraction cavity arrays using two secondary flows

    International Nuclear Information System (INIS)

    The focusing of particles has a variety of applications in industry and biomedicine, including wastewater purification, fermentation filtration, and pathogen detection in flow cytometry, etc. In this paper a novel inertial microfluidic device using two secondary flows to focus particles is presented. The geometry of the proposed microfluidic channel is a simple straight channel with asymmetrically patterned triangular expansion–contraction cavity arrays. Three different focusing patterns were observed under different flow conditions: (1) a single focusing streak on the cavity side; (2) double focusing streaks on both sides; (3) half of the particles were focused on the opposite side of the cavity, while the other particles were trapped by a horizontal vortex in the cavity. The focusing performance was studied comprehensively up to flow rates of 700 µl min−1. The focusing mechanism was investigated by analysing the balance of forces between the inertial lift forces and secondary flow drag in the cross section. The influence of particle size and cavity geometry on the focusing performance was also studied. The experimental results showed that more precise focusing could be obtained with large particles, some of which even showed a single-particle focusing streak in the horizontal plane. Meanwhile, the focusing patterns and their working conditions could be adjusted by the geometry of the cavity. This novel inertial microfluidic device could offer a continuous, sheathless, and high-throughput performance, which can be potentially applied to high-speed flow cytometry or the extraction of blood cells. (paper)

  12. Effects of a poloidally asymmetric ionization source on toroidal drift wave stability and the generation of sheared parallel flow

    International Nuclear Information System (INIS)

    The effects of a poloidally asymmetric ionization source on both dissipative toroidal drift wave stability and the generation of mean sheared parallel flow are examined. The first part of this work extends the development of a local model of ionization-driven drift wave turbulence [Phys. Fluids B 4, 877 (1992)] to include the effects of magnetic shear and poloidal source asymmetry, as well as poloidal mode coupling due to both magnetic drifts and the source asymmetry. Numerical and analytic investigation confirm that ionization effects can destabilize collisional toroidal drift waves. However, the mode structure is determined primarily by the magnetic drifts, and is not overly effected by the poloidal source asymmetry. The ionization source drives a purely inward particle flux, which can explain the anomalously rapid uptake of particles which occurs in response to gas puffing. In the second part of this work, the role poloidal asymmetries in both the source and turbulent particle diffusion play in the generation of sheared mean parallel flow is examined. Analysis indicates that predictions of sonic parallel shear flow [vparallel(r)∼cs] are an unphysical result of the assumption of purely parallel flow (i.e., vperpendicular=0) and the neglect of turbulent parallel momentum transport. Results indicate that the flow produced is subcritical to the parallel shear flow instability when diamagnetic effects are properly considered

  13. Analysis of thermal tests in a pressurized water reactor having asymmetric loop flows

    International Nuclear Information System (INIS)

    An analysis was made of three-dimensional steady-state computations from the thermal mixing tests performed in the Oconee 1 pressurized water reactor at the beginning of fuel cycle 6 early in 1980 under the sponsorship of the Electric Power Research Institute. It was found that detailed modeling of the 52 asymmetrically located instrument guide tubes, together with the various structures in the lower plenum, yielded generally good agreement with the data (within 10F). Most of the thermal mixing trends at the entrance to the core and midplane deduced from the 29-thermocouple reading were correctly computed

  14. Peristaltic flow of Johnson-Segalman fluid in asymmetric channel with convective boundary conditions

    Institute of Scientific and Technical Information of China (English)

    H YASMIN; T HAYAT; A ALSAEDI; HH ALSULAMI

    2014-01-01

    This work is concerned with the peristaltic transport of the Johnson-Segalman fluid in an asymmetric channel with convective boundary conditions. The mathematical modeling is based upon the conservation laws of mass, linear momentum, and energy. The resulting equations are solved after long wavelength and low Reynolds number are used. The results for the axial pressure gradient, velocity, and temperature profiles are obtained for small Weissenberg number. The expressions of the pressure gra-dient, velocity, and temperature are analyzed for various embedded parameters. Pumping and trapping phenomena are also explored.

  15. Asymmetric magnetic reconnection with a flow shear and applications to the magnetopause

    CERN Document Server

    Doss, C E; Cassak, P A; Wilder, F D; Eriksson, S; Drake, J F

    2015-01-01

    We perform a theoretical and numerical study of anti-parallel 2D magnetic reconnection with asymmetries in the density and reconnecting magnetic field strength in addition to a bulk flow shear across the reconnection site in the plane of the reconnecting fields, which commonly occurs at planetary magnetospheres. We predict the speed at which an isolated X-line is convected by the flow, the reconnection rate, and the critical flow speed at which reconnection no longer takes place for arbitrary reconnecting magnetic field strengths, densities, and upstream flow speeds, and confirm the results with two-fluid numerical simulations. The predictions and simulation results counter the prevailing model of reconnection at Earth's dayside magnetopause which says reconnection occurs with a stationary X-line for sub-Alfvenic magnetosheath flow, reconnection occurs but the X-line convects for magnetosheath flows between the Alfven speed and double the Alfven speed, and reconnection does not occur for magnetosheath flows g...

  16. On the directed transverse flow and the relation between symmetric and asymmetric collisions

    International Nuclear Information System (INIS)

    It is now well established that the collective flow in heavy-ion collision has the ability to pin down the nuclear equation of state (EOS). A complete understanding of the fragment flow can give us knowledge about the bulk properties of nuclear matter and the relation among pressure, temperature and density of the compressed nuclear matter. Last two decade observed a vigorous developments regarding in-plane flow or sideward flow of nuclear matter. The in-plane flow is a complex many body dynamics which is highly influenced by the incident energy and the mass of colliding partners. At low incident energies, the collective flow is negative as the phenomenon of fusion, fission and dynamical cluster decay dominates the physics. At higher incident energies, repulsive nucleon-nucleon (NN) scattering take a lead and the particles are forced to move towards forward hemisphere making collective flow positive

  17. Sediment Micromechanics in Sheet Flows Induced by Asymmetric Waves: A CFD-DEM Study

    CERN Document Server

    Sun, Rui

    2016-01-01

    Understanding the sediment transport in oscillatory flows is essential to the investigation of the overall sediment budget for coastal regions. This overall budget is crucial for the prediction of the morphological change of the coastline in engineering applications. Since the sediment transport in oscillatory flows is dense particle-laden flow, appropriate modeling of the particle interaction is critical. Although traditional two-fluid approaches have been applied to the study of sediment transport in oscillatory flows, the approaches do not resolve the interaction of the particles. Particle-resolved modeling of sediment transport in oscillatory flows and the study of micromechanics of sediment particles are still lacking. In this work, a parallel CFD-DEM solver SediFoam that can resolve the inter-particle collision is applied to study the granular micromechanics of sediment particles in oscillatory flows. The results obtained from SediFoam are validated by the experimental data of coarse and medium sands. T...

  18. Studying the vibrations of rod bundles under asymmetrical flow-round

    International Nuclear Information System (INIS)

    The results of experimental invesigation into vibrations of peripheral tubes in a rod bundle initiated by coolant flow are presented. Conditions of flowing around the rod bundles with different deflections in the channel geometry and hydrodynamics of coolant flow are simulated on special models. Data characterizing the dependence of the rod vibration amplitudes on the value of the gap between the bundle and the channel as well as the effect of the transverse constituent of the coolant overflow from the centre of the bundle to periphery on the rod vibration amplitude in one- and two-phase flows are obtained

  19. Assessment of contrast flow modification in aneurysms treated with closed-cell self-deploying asymmetric vascular stents (SAVS).

    Science.gov (United States)

    Ionita, Ciprian N; Wang, Weiyuan; Bednarek, Daniel R; Rudin, Stephen

    2010-01-01

    The Asymmetric Vascular Stent (AVS) for intracranial aneurysm (IA) treatment is an experimental device, specially designed for intra-aneurysmal blood flow diversion and thrombosis promotion. The stent has a low-porous patch to cover only the aneurysm neck while the rest of the stent is very porous to avoid blockage of adjacent branches. The latest AVS design is similar to state-of-art, closed-cell, self-expanding, neurovascular stent. The stents were used to treat sixteen rabbit-elastase aneurysm models. The treatment effect was analyzed using normalized-time-density-curves (NTDC) measured by pixel-value integration over a region-of-interest containing the aneurysm. Normalization constant was the total bolus injection determined angiographically. Based on NTDC measurement, five quantities were derived to describe the contrast flow. Two are related to the amount of contrast entering the aneurysm: NTDC peak and NTDC input slope. The other three are related to contrast presence in the aneurysmal dome: time-to-peak (TTP), wash-out-time (WOT) and mean-transit-time (MTT). Flow modification descriptions using the contrast related quantities were expressed as a pre-/post-stented NTDC parameter ratio, while the time related quantities were expressed as a post-/pre-stented ratio, so that ratios smaller than one indicate a desired effect. Thirteen aneurysms were treated successfully and achieved significant aneurysm occlusion. For these cases, the resulting average parameters were: peak-ratio=0.17±0.21; input-slope-ratio=0.19±0.24, TTP-ratio=0.17±0.21, WOT-ratio=0.58±0.73 and MTT-ratio=0.65±0.97). All the quantities revealed decreased aneurysmal flow due to blood flow diversion using the new self-expanding asymmetrical vascular stent (SAVS). Treatment outcome results and angiographic analysis indicate that the new self-deploying stent design has great potential for clinical implementation. PMID:21243093

  20. Computation of the viscous supersonic flow over symmetrical and asymmetrical external axial corners

    Science.gov (United States)

    Kutler, P.; Pulliam, T. H.; Vigneron, Y. C.

    1978-01-01

    The primary objective of the reported investigation is the computational verification of the experimental results obtained by Salas and Daywitt (1978). Two existing computer codes were used to compute the supersonic flow field surrounding the external axial corner. For the inviscid and turbulent flow results, the unsteady, three-dimensional implicit code of Pulliam and Steger (1978) was used. For the laminar flow results, the unsteady two-dimensional explicit procedure of Vigneron et al. (1977) was employed. Inviscid solutions for a symmetric configuration with a rounded corner resulted in either single or triple surface crossflow stagnation point flows, depending on the corner radius. Numerical results obtained for the same symmetric configuration tested experimentally show the crossflow in the vicinity of the corner to be away from the corner and thus in agreement with the experimental oil flow results.

  1. Asymmetric-detection time-stretch optical microscopy (ATOM) for ultrafast high-contrast cellular imaging in flow

    CERN Document Server

    Wong, Terence T W; Ho, Kenneth K Y; Tang, Matthew Y H; Robles, Joseph D F; Wei, Xiaoming; Chan, Antony C S; Tang, Anson H L; Lam, Edmund Y; Wong, Kenneth K Y; Chan, Godfrey C F; Shum, Ho Cheung; Tsia, Kevin K

    2013-01-01

    Accelerating imaging speed in optical microscopy is often realized at the expense of image contrast, image resolution, and detection sensitivity- a common predicament for advancing high-speed and high-throughput cellular imaging. We here demonstrate a new imaging approach, called asymmetric-detection time-stretch optical microscopy (ATOM), which can deliver ultrafast label-free high-contrast flow imaging with well delineated cellular morphological resolution and in-line optical image amplification to overcome the compromised imaging sensitivity at high speed. We show that ATOM can separately reveal the enhanced phase-gradient and absorption contrast in microfluidic live-cell imaging at a flow speed as high as ~10 m/s, corresponding to an imaging throughput of ~100,000 cells/sec. ATOM could thus be the enabling platform to meet the pressing need for intercalating optical microscopy in cellular assay, e.g. imaging flow cytometry- permitting high-throughput access to the morphological information of the individu...

  2. On laminar hydromagnetic mixed convection flow in a vertical channel with symmetric and asymmetric wall heating conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chamkha, A.J. [Kuwait University, Safat (Kuwait). Dept. of Mechanical Engineering

    2002-06-01

    The problem of hydromagnetic fully developed laminar mixed convection flow in a vertical channel with symmetric and asymmetric wall heating conditions in the presence or absence of heat generation or absorption effects is considered. Through proper choice of dimensionless variables, the governing equations are developed and three types of thermal boundary conditions are prescribed. These thermal boundary conditions are isothermal-isothermal, isoflux-isothermal, and isothermal-isoflux for the left-right walls of the channel. Analytical solutions for the velocity and temperature profiles for various special cases of the problem are reported. In addition, closed-form expressions for the Nusselt numbers and reversal flow conditions at both the left and right channel walls are derived. The general problem which includes the effects of both viscous dissipation and Joule heating is solved by an implicit finite-difference scheme. Favorable comparisons of special cases with previously published work are obtained. A selected set of graphical results illustrating the effects of the various parameters involved in the problem including viscous and magnetic dissipations on the velocity and temperature profiles, as well as flow reversal situations and Nusselt numbers, is presented and discussed. (author)

  3. Left-right asymmetric holographic RG flow with gravitational Chern-Simons term

    International Nuclear Information System (INIS)

    We consider the holographic renormalization group (RG) flow in three-dimensional gravity with the gravitational Chern-Simons term coupled to some scalar fields. We apply the canonical approach to this higher derivative case and employ the Hamilton-Jacobi formalism to analyze the flow equations of two-dimensional field theory. Especially we obtain flow equations of Weyl and gravitational anomalies, and derive c-functions for left and right moving modes. Both of them are monotonically non-increasing along the flow, and the difference between them is determined by the coefficient of the gravitational Chern-Simons term. This is completely consistent with the Zamolodchikov's c-theorem for parity-violating two-dimensional quantum field theories.

  4. Development of Signal Processing Technique of Digital Speckle Tomography for Analysis of Three-Dimensional Density Distributions of Unsteady and Asymmetric Gas Flow

    International Nuclear Information System (INIS)

    Transient and asymmetric density distributions of butane flow have been investigated from laser image signals by developed three-dimensional digital speckle tomography. Moved signals of speckles have been captured by multiple CCD images in three angles of view simultaneously because the flows were asymmetric and transient. The signals of speckle movements between no flow and downward butane flow from a circular half opening have been calculated by a cross-correlation tracking method so that those distances can be transferred to deflection angles of laser rays fur density gradients. The three-dimensional density fields have been reconstructed from the fringe shift signal which is integrated from the deflection angle by a real-time multiplicative algebraic reconstruction technique (MART)

  5. Numerical simulation of asymmetric and nonstationary turbulent flow of acute cones by supersonic flux

    International Nuclear Information System (INIS)

    The results of the numerical simulation of the supersonic turbulent flow-around of the thin circular cones at the incidence angles of α ≥ 3 θc, where θc is a cone semiaperture angle are presented. The task is solved with the frames of the local-conical approximation of the Reynolds equations system with application of the differential single-parameter turbulence model. The numerical solutions are determined through the nonimplicit finite difference scheme of the constant direction. The main attention is paid to violation of the symmetry and stability of the cross-sectional stalled flow-around

  6. PC solutions for heat transfer and fluid flow downstream of an abrupt, asymmetric enlargement in a channel

    International Nuclear Information System (INIS)

    An IBM PC was used to obtain finite-difference solutions to a complex heat transfer and fluid flow problem in which the solution domain contained nearly 6000 grid points. The investigated problem was the abrupt, asymmetric enlargement of a parallel-plate channel. The enlargement takes the form of a backward-facing step, the presence of which causes separation of the flow. Heat transfer occurred at the channel wall which extended downstream from the foot of the step. The present velocity solutions were shown to be at least as accurate as prior numerical solutions and served to extend the range of investigated enlargements. The variation of the local Nusselt number with the Reynolds number took on different forms at various axial distances from the enlargement step. In a region extending downstream from the step, the Nusselt number actually decreased monotonically with increasing Reynolds number. Farther downstream, the Nusselt-Reynolds variation was monotonically increasing, while still farther downstream, the Nusselt number was independent of the Reynolds number

  7. An asymmetrical λ-foot of condensing steam flow in the IMP PAN nozzle

    International Nuclear Information System (INIS)

    In the present paper we have focused on the precise prediction of the spontaneous condensation phenomena in wet steam flow. Novelty of our approach lies on modelling both the moment of initiation of a phase transition, as well as the moment of its reverse progress – called here re-vaporization of the condensate phase. The practical issue is to elaborate of a model of spontaneous condensation/vaporization of water steam flow under low-pressure conditions by using methodology of non-equilibrium thermodynamics [2]. The basic tests including comparison with an experimental data have been performed using the IMP PAN nozzle with the de Laval geometry [1]. Having observed the finishing of a foggy flow within the shock wave, according to Puzyrewski's postulate [1], we would like to analyse the topography of the shock wave pattern in the IMP PAN symmetric nozzle. This phenomenon, independently from a type of compressible fluid, has been observed to be the result of interaction between a normal shock wave and the boundary layer – it has been known as a λ – foot structure [3]. The asymmetry of the shock structure is measured by optical system and visible since the foggy flow can be easily observed. Our paper is a trial towards to an explanation of this problem.

  8. Numerical studies of asymmetric adiabatic accretion flow - The effect of velocity gradients

    International Nuclear Information System (INIS)

    A numerical study of the time variation of the angular momentum and mass capture rates for a central object accreting from a uniform medium with a velocity gradient transverse to the direction of the mean flow is presented, covering a range of velocity asymmetries and Mach numbers in the incident flow. It is found that the mass accretion rate in a given evolutionary sequence varies in an irregular manner, with the matter accreting onto the central object from either a continuously moving accretion wake or from an accretion disk. The implications of the results from the study of short-term fluctuations observed in the pulse period and luminosity of X-ray pulsars are discussed. 35 refs

  9. Design and Fabrication of a Flow Delivery Microdevice with Asymmetric Microelectrodes Pairs

    International Nuclear Information System (INIS)

    A microdevice using AC electrokinetic flow and negative dielectrophoresis for cell delivery is proposed, designed and fabricated. The device is made from an unequal width interdigitated microelectrode located at the bottom of microchannels, with AC voltage applied to the small and large electrode. Negative dielectrophoresis is used to prevent the cells from sinking down to the bottom of delivery channel. The flow rate is affected by the electrode pair dimensions, applied frequency and voltage and are analysed. The device electrode width is from 4μm to 20μm and it is microfabricated on glass wafer using gold thin film. 3 microchannels connected to 2 reservoirs are covered by the electrode pair for the delivery channel. SU-8 micromold is used for the channels' PDMS fabrication

  10. Collective flow and balance energy in asymmetric heavy-ion collisions

    International Nuclear Information System (INIS)

    Heavy-ion collisions at intermediate energy provide a useful tool to determine the nuclear matter equation of state as well as in-medium nucleon-nucleon (nn) cross-section. We therefore, aim to study the transverse in-plane flow as well as its disappearance for different colliding nuclei with varying asymmetry. We plan to address this question using quantum molecular dynamics (QMD) model

  11. Theoretical Analysis and Experimental Researches regarding the Asymmetrical Fluid Flow Applied in Aeronautics

    OpenAIRE

    2015-01-01

    The current paper has been written in order to find the best solutions to replace the antitorque rotor of single-rotor helicopters, with removal of its disadvantages through the Coandă Effect. This would significantly increase the flight performance. The research mainly aims at obtaining a controlled lateral force due to Coandă flows through the tail boom, a force which would be useful for the stabilization needed because of the lifting rotor during the flight of single-rotor helicopters.

  12. Unsteady supersonic flow around delta wings with symmetric and asymmetric flaps oscillation

    Science.gov (United States)

    Kandil, Osama A.; Salman, Ahmed A.

    1991-01-01

    A parametric study is presented to investigate the effect of reduced frequency of the leading-edge flaps on the locally-conical, unsteady, supersonic flow around a delta wing. This study covers symmetric and antisymmetric forced oscillation of the leading-edge flaps. The effects of the freestream Mach number and angle of attack are also presented. The problem is solved using time-accurate integration of the unsteady, compressible, thin-layer Navier-Stokes equations and the unsteady, linearized, Navier-displacement equations. The delta wing is of aspect ratio of 1.5 and its leading-edge flaps are hinged at 65 percent of the local-half span length. The reduced frequency is varied between 2 pi and pi/2. Two supersonic flow conditions have been investigated; the first is for a freestream Mach number of 2.4 and an angle of attack of 19 deg and the second is for a freestream Mach number of 1.5 and an angle attack of 15 deg.

  13. CFD modeling of two phase flow in asymmetric rotating disc contactor

    International Nuclear Information System (INIS)

    The present work includes CFD modeling of ARDC to generate data related to hydrodynamics in different regions and to understand phase interaction for two phase flow. The system fluids were phosphoric acid as continuous phase and Organo-phosphorus solvent as dispersed phase for uranium extraction from phosphoric acid. Plots of parameters related to hydrodynamics and mass transfer like axial velocity, radial velocity, velocity magnitude, and pressure and volume fraction of phases are generated which are important for design and to understand the contacting phenomenon in multistage agitated column. Time dependent analysis of two phase interaction has been done to simulate actual phenomenon. Special emphasis is given to the critical design and operation parameters. Resultant to the above work, for a typical case of 250 rpm, light phase volume friction is displayed and results of simulation are summarized

  14. Measurements of the asymmetric dynamic sheath around a pulse biased sphere immersed in flowing metal plasma

    International Nuclear Information System (INIS)

    A long-probe technique was utilized to record the expansion and retreat of the dynamic sheath around a spherical substrate immersed in pulsed cathode arc metal plasma. Positively biased, long cylindrical probes were placed on the side and downstream of a negatively pulsed biased stainless steel sphere of 1 in. (25.4 mm) diameter. The amplitude and width of the negative high voltage pulses (HVPs) were 2 kV, 5 kV, 10 kV, and 2 μs, 4 μs, 10 μs, respectively. The variation of the probe (electron) current during the HVP is a direct measure for the sheath expansion and retreat. Maximum sheath sizes were determined for the different parameters of the HVP. The expected rarefaction zone behind the biased sphere (wake) due to the fast plasma flow was clearly established and quantified.

  15. Measurements of the asymmetric, dynamic sheath around a pulse biased sphere immersed in flowing metal plasma

    Energy Technology Data Exchange (ETDEWEB)

    Anders, Andre; Wu, Hongchen; Anders, Andre

    2008-06-13

    A long-probe technique was utilized to record the expansion and retreat of the dynamic sheath around a spherical substrate immersed in pulsed cathode arc metal plasma. Positively biased, long cylindrical probes were placed on the side and downstream of a negatively pulsed biased stainless steel sphere of 1" (25.4 mm) diameter. The amplitude and width of the negative high voltage pulses (HVP) were 2 kV, 5 kV, 10 kV, and 2 mu s, 4 mu s, 10 mu s, respectively. The variation of the probe (electron) current during the HVP is a direct measure for the sheath expansion and retreat. Maximum sheath sizes were determined for the different parameters of the HVP. The expected rarefaction zone behind the biased sphere (wake) due to the fast plasma flow was clearly established and quantified.

  16. Dean-flow-coupled elasto-inertial three-dimensional particle focusing under viscoelastic flow in a straight channel with asymmetrical expansion-contraction cavity arrays.

    Science.gov (United States)

    Yuan, D; Zhang, J; Yan, S; Pan, C; Alici, G; Nguyen, N T; Li, W H

    2015-07-01

    In this paper, 3D particle focusing in a straight channel with asymmetrical expansion-contraction cavity arrays (ECCA channel) is achieved by exploiting the dean-flow-coupled elasto-inertial effects. First, the mechanism of particle focusing in both Newtonian and non-Newtonian fluids was introduced. Then particle focusing was demonstrated experimentally in this channel with Newtonian and non-Newtonian fluids using three different sized particles (3.2 μm, 4.8 μm, and 13 μm), respectively. Also, the effects of dean flow (or secondary flow) induced by expansion-contraction cavity arrays were highlighted by comparing the particle distributions in a single straight rectangular channel with that in the ECCA channel. Finally, the influences of flow rates and distances from the inlet on focusing performance in the ECCA channel were studied. The results show that in the ECCA channel particles are focused on the cavity side in Newtonian fluid due to the synthesis effects of inertial and dean-drag force, whereas the particles are focused on the opposite cavity side in non-Newtonian fluid due to the addition of viscoelastic force. Compared with the focusing performance in Newtonian fluid, the particles are more easily and better focused in non-Newtonian fluid. Besides, the Dean flow in visco-elastic fluid in the ECCA channel improves the particle focusing performance compared with that in a straight channel. A further advantage is three-dimensional (3D) particle focusing that in non-Newtonian fluid is realized according to the lateral side view of the channel while only two-dimensional (2D) particle focusing can be achieved in Newtonian fluid. Conclusively, this novel Dean-flow-coupled elasto-inertial microfluidic device could offer a continuous, sheathless, and high throughput (>10 000 s(-1)) 3D focusing performance, which may be valuable in various applications from high speed flow cytometry to cell counting, sorting, and analysis. PMID:26339309

  17. Impact of chevron spacing and asymmetric distribution on supersonic jet acoustics and flow

    Science.gov (United States)

    Heeb, N.; Gutmark, E.; Kailasanath, K.

    2016-05-01

    An experimental investigation into the effect of chevron spacing and distribution on supersonic jets was performed. Cross-stream and streamwise particle imaging velocimetry measurements were used to relate flow field modification to sound field changes measured by far-field microphones in the overexpanded, ideally expanded, and underexpanded regimes. Drastic modification of the jet cross-section was achieved by the investigated configurations, with both elliptic and triangular shapes attained downstream. Consequently, screech was nearly eliminated with reductions in the range of 10-25 dB depending on the operating condition. Analysis of the streamwise velocity indicated that both the mean shock spacing and strength were reduced resulting in an increase in the broadband shock associated noise spectral peak frequency and a reduction in the amplitude, respectively. Maximum broadband shock associated noise amplitude reductions were in the 5-7 dB range. Chevron proximity was found to be the primary driver of peak vorticity production, though persistence followed the opposite trend. The integrated streamwise vorticity modulus was found to be correlated with peak large scale turbulent mixing noise reduction, though optimal overall sound pressure level reductions did not necessarily follow due to the shock/fine scale mixing noise sources. Optimal large scale mixing noise reductions were in the 5-6 dB range.

  18. An asymmetric upwind flow, Yellow Sea Warm Current: 1. New observations in the western Yellow Sea

    Science.gov (United States)

    Lin, Xiaopei; Yang, Jiayan; Guo, Jingsong; Zhang, Zhixin; Yin, Yuqi; Song, Xiangzhou; Zhang, Xiaohui

    2011-04-01

    The winter water mass along the Yellow Sea Trough (YST), especially on the western side of the trough, is considerably warmer and saltier than the ambient shelf water mass. This observed tongue-shape hydrographic feature implies the existence of a winter along-trough and onshore current, often referred to as the Yellow Sea Warm Current (YSWC). However, the YSWC has not been confirmed by direct current measurements and therefore skepticism remains regarding its existence. Some studies suggest that the presence of the warm water could be due to frontal instability, eddies, or synoptic scale wind bursts. It is noted that in situ observations used in most previous studies were from the central and eastern sides of the YST even though it is known that the warm water core is more pronounced along the western side. Data from the western side have been scarce. Here we present a set of newly available Chinese observations, including some from a coordinated effort involving three Chinese vessels in the western YST during the 2006-2007 winter. The data show unambiguously the existence of the warm current on the western side of YST. Both the current and hydrography observations indicate a dominant barotropic structure of YSWC. The westward deviation of YSWC axis is particularly obvious to the south of 35°N and is clearly associated with an onshore movement of warm water. To the north of 35°N, the YSWC flows along the bathymetry with slightly downslope movement. We conclude that the barotropic current is mainly responsible for the warm water intrusion, while the Ekman and baroclinic currents play an important but secondary role. These observations help fill an observational gap and establish a more complete view of the YSWC.

  19. A sheath model of asymmetric heat flow to a poloidal limiter

    International Nuclear Information System (INIS)

    Experimental results on JET and other tokamaks with poloidal limiters have shown that there is typically a 50% difference in heat flow to the two sides of a poloidal limiter. Defining the 'ion' side of a poloidal limiter as that which would receive a toroidal ion current in the same direction as the induced toroidal current of the tokamak, and the 'electron' side as the other side, it is estimated from experimental data by Lowry that the energy flux received by the 'electron' side is typically half of that on the 'ion' side. The recent review of the scrape-off layer by Stangeby and McCracken also contains evidence to support this, even suggesting a factor of 10 in asymmetry of density. Lowry has suggested that this asymmetry can arise through the preferential arrival of ions into the outer scrape-off layer with toroidal angular momentum in the Jφ direction. This arises from a consideration of ion drift orbits in the banana neo-classical regime; at the plasma edge parts of phase space of the ion distribution function are depleted, because the orbits of these ions would originate at an earlier time from further away from the minor axis. Such a mechanism would also lead to a steady exchange of toroidal angular momentum between the plasma and the limiter. The effect would be reversed on a poloidal limiter on the inside of the torus as compared to one on the outside. In this paper a completely model is developed which is based on an extension of Child-Langmuir sheath theory. (author) 5 refs

  20. Influence of magnetic field and heat transfer on peristaltic flow of Jeffrey fluid through a porous medium in an asymmetric channel

    OpenAIRE

    C. Vasudev; U.Rajeswara Rao; M. V. Subba Reddy; G. Prabhakara Rao

    2010-01-01

    In this paper, we studied the effects of heat transfer and magnetic field on the peristaltic flow of a Jeffrey fluid through a porous medium in an asymmetric channel under the assumptions of long wavelength and low Reynolds number. Expressions for the velocity and pressure gradient are obtained analytically. The effects of Hartmann number, Darcy number, phase shift, Jeffrey fluid parameter and upper and lower wave amplitudes on the pumping characteristics and the temperature field are discuss...

  1. Measurements of ion temperature and flow velocity using symmetric and asymmetric double probes in the boundary plasma of the JFT-2M tokamak

    International Nuclear Information System (INIS)

    The radial profiles of the ion temperature as well as the flow velocity have been measured by using rotatable symmetric and asymmetric double probes in the boundary plasma of the JFT-2M tokamak. It has been found that the ion temperature is higher than the electron temperature by a factor of about 10, and the flow velocity is 0.2-0.3 of the ion sound velocity in the SOL for both ohmic and NB injection heating. These data can help to determine the cross-field thermal diffusivity in tokamak boundary plasma. (author)

  2. Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetrical Flow Control-Part II: Nonaxisymmetrical Self-Recirculation Casing Treatment.

    Science.gov (United States)

    Zheng, Xinqian; Zhang, Yangjun; Yang, Mingyang; Bamba, Takahiro; Tamaki, Hideaki

    2013-03-01

    This is part II of a two-part paper involving the development of an asymmetrical flow control method to widen the operating range of a turbocharger centrifugal compressor with high-pressure ratio. A nonaxisymmetrical self-recirculation casing treatment (SRCT) as an instance of asymmetrical flow control method is presented. Experimental and numerical methods were used to investigate the impact of nonaxisymmetrical SRCT on the surge point of the centrifugal compressor. First, the influence of the geometry of a symmetric SRCT on the compressor performance was studied by means of numerical simulation. The key parameter of the SRCT was found to be the distance from the main blade leading edge to the rear groove (Sr). Next, several arrangements of a nonaxisymmetrical SRCT were designed, based on flow analysis presented in part I. Then, a series of experiments were carried out to analyze the influence of nonaxisymmetrical SRCT on the compressor performance. Results show that the nonaxisymmetrical SRCT has a certain influence on the performance and has a larger potential for stability improvement than the traditional symmetric SRCT. For the investigated SRCT, the surge flow rate of the compressor with the nonaxisymmetrical SRCTs is about 10% lower than that of the compressor with symmetric SRCT. The largest surge margin (smallest surge flow rate) can be obtained when the phase of the largest Sr is coincident with the phase of the minimum static pressure in the vicinity of the leading edge of the splitter blades. PMID:24891758

  3. Entropy analysis for the Couette flow of non-Newtonian fluids between asymmetrically heated parallel plates: effect of applied pressure gradient

    International Nuclear Information System (INIS)

    The current study discusses the irreversibility analysis for the Couette flow of non-Newtonian fluids between two asymmetrically heated parallel plates for two different flow configurations viz., under the application of a weak pressure gradient and for a relatively strong pressure gradient. The plates are kept at different constant temperatures, while the effect of viscous dissipation is included in the analysis. The study explores the combined consequences of the rheological effect of the fluids, the movement of the upper plate, and the magnitude of the externally applied pressure gradient on the irreversibility generation rate of the system as manifested by the variation of the volumetric entropy generation number, irreversibility distribution ratio, and the Bejan number. Intricate interplay between the effects of fluid friction and heat transfer in dictating the irreversibility of the system is highlighted for different degrees of asymmetrical wall heating and upper-plate velocity. The study further shows that, for a given degree of asymmetrical wall heating, the irreversibility generation rate alters with the alteration in the rheological behaviour of the fluid. (paper)

  4. Computational Analysis of Wake Field Flow between Multiple Identical Spheres

    Science.gov (United States)

    Brand, Wesley; Greenslit, Morton; Klassen, Zach; Hastings, Jay; Matson, William

    2014-11-01

    It is well understood both that objects moving through a fluid perturb the motion of nearby objects in the same fluid and that some configurations of objects moving through a fluid have little inter-object perturbation, such as a flock of birds flying in a V-formation. However, there is presently no known method for predicting what configurations of objects will be stable while moving through a fluid. Previous work has failed to find such stable configurations because of the computational complexity of finding individual solutions. In this research, the motions of two spheres in water were simulated and combinations of those simulations were used to extrapolate the motions of multiple spheres and to find configurations where the lateral forces on each sphere were negligible and the vertical forces on each sphere were equivalent. Two and three sphere arrangements were simulated in COMSOL Multiphysics and Mathematica was used both to demonstrate that combinations of two sphere cases are identical to three sphere cases and to identify stable configurations of three or more spheres. This new approach is expected to simplify optimization of aerodynamic configurations and applications such as naval and aerospace architecture and racecar driving. Advisor.

  5. Large Mass Flux Differences for Opposite Flow Directions of a Condensable Gas through an Asymmetric Porous Membrane

    Czech Academy of Sciences Publication Activity Database

    Uchytil, Petr; Loimer, T.

    2014-01-01

    Roč. 470, NOV 15 (2014), s. 451-457. ISSN 0376-7388 R&D Projects: GA MŠk 7AMB12AT010; GA MŠk(CZ) 7AMB14AT011 Institutional support: RVO:67985858 Keywords : condensation * vapor permeation * asymmetric membranes Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 5.056, year: 2014

  6. On Combined Effects of Heat Transfer and Chemical Reaction for the Flow through an Asymmetric Channel with Orthogonally Deformable Porous Walls

    Directory of Open Access Journals (Sweden)

    Syed Tauseef Mohyud-Din

    2016-01-01

    Full Text Available The combined effects of heat transfer and chemical reaction are studied for the flow through a semi-infinite asymmetric channel with orthogonally deformable porous walls. The similarity transforms have been used to reduce the conservation laws to a corresponding system of nonlinear ordinary differential equations. The resulting equations are solved, both analytically and numerically, by using Homotopy Analysis Method (HAM and the fourth-order Runge-Kutta (RK-4 method, respectively. The convergence of the analytical solution is assured through the so-called total squared residual error analysis. The optimal values of auxiliary parameters are obtained by minimizing the total squared residual error.

  7. Influence of magnetic field and heat transfer on peristaltic flow of Jeffrey fluid through a porous medium in an asymmetric channel

    Directory of Open Access Journals (Sweden)

    C. Vasudev

    2010-12-01

    Full Text Available In this paper, we studied the effects of heat transfer and magnetic field on the peristaltic flow of a Jeffrey fluid through a porous medium in an asymmetric channel under the assumptions of long wavelength and low Reynolds number. Expressions for the velocity and pressure gradient are obtained analytically. The effects of Hartmann number, Darcy number, phase shift, Jeffrey fluid parameter and upper and lower wave amplitudes on the pumping characteristics and the temperature field are discussed through graphs in detail.

  8. Assessment of the CATHARE 3D capabilities in predicting the temperature mixing under asymmetric buoyant driven flow conditions

    International Nuclear Information System (INIS)

    Highlights: • We assess the coolant mixing in the RPV downcomer and the core lower plenum under buoyant asymmetric conditions. • We evaluate the capabilities of the thermal-hydralic system computer codes to simulate such phenomenon. • We considered the PKL2-ROCOM T1.1 and T2.1 experimental tests. • We used the 3D features of the CATHARE thermal-hydraulic system code to simulate the experiments. • Acceptable prediction of the buoyant mixing in the downcomer is obtained. - Abstract: Coolant mixing in the reactor vessel of a pressurized water reactor constitutes a key parameter for predicting the core behaviour under abnormal asymmetric cooling conditions. This issue was recently investigated within the experimental framework of the OECD/PKL-2 project. The aim was twofold: to assess the coolant mixing in the vessel downcomer and the core lower plenum under buoyant asymmetric cooling loops, as well as to evaluate the capabilities of computer codes in simulating such phenomenon. It is commonly known that CFD codes are applied for this objective using millions of nodes and large computer resources. However, thermal-hydraulic system codes having the 3D vessel models could also be considered for such purpose. Indeed, these codes benefit from large validation background, require less computational resources and include 3D capabilities that are up to now not fully exploited. In this framework the CATHARE 3D models are assessed against two asymmetrical buoyant mixing experimental tests performed at the ROCOM facility. The outcomes of the current study show good prediction potentialities of the 3D thermal-hydraulic system codes. However their applicability to NPP scale has to be further investigated experimentally and analytically as well

  9. Assessment of the CATHARE 3D capabilities in predicting the temperature mixing under asymmetric buoyant driven flow conditions

    Energy Technology Data Exchange (ETDEWEB)

    Bousbia Salah, Anis, E-mail: anis.bousbiasalah@belv.be; Vlassenbroeck, Jacques

    2013-12-15

    Highlights: • We assess the coolant mixing in the RPV downcomer and the core lower plenum under buoyant asymmetric conditions. • We evaluate the capabilities of the thermal-hydralic system computer codes to simulate such phenomenon. • We considered the PKL2-ROCOM T1.1 and T2.1 experimental tests. • We used the 3D features of the CATHARE thermal-hydraulic system code to simulate the experiments. • Acceptable prediction of the buoyant mixing in the downcomer is obtained. - Abstract: Coolant mixing in the reactor vessel of a pressurized water reactor constitutes a key parameter for predicting the core behaviour under abnormal asymmetric cooling conditions. This issue was recently investigated within the experimental framework of the OECD/PKL-2 project. The aim was twofold: to assess the coolant mixing in the vessel downcomer and the core lower plenum under buoyant asymmetric cooling loops, as well as to evaluate the capabilities of computer codes in simulating such phenomenon. It is commonly known that CFD codes are applied for this objective using millions of nodes and large computer resources. However, thermal-hydraulic system codes having the 3D vessel models could also be considered for such purpose. Indeed, these codes benefit from large validation background, require less computational resources and include 3D capabilities that are up to now not fully exploited. In this framework the CATHARE 3D models are assessed against two asymmetrical buoyant mixing experimental tests performed at the ROCOM facility. The outcomes of the current study show good prediction potentialities of the 3D thermal-hydraulic system codes. However their applicability to NPP scale has to be further investigated experimentally and analytically as well.

  10. Asymmetric information and economics

    Science.gov (United States)

    Frieden, B. Roy; Hawkins, Raymond J.

    2010-01-01

    We present an expression of the economic concept of asymmetric information with which it is possible to derive the dynamical laws of an economy. To illustrate the utility of this approach we show how the assumption of optimal information flow leads to a general class of investment strategies including the well-known Q theory of Tobin. Novel consequences of this formalism include a natural definition of market efficiency and an uncertainty principle relating capital stock and investment flow.

  11. Asymmetric AB3 Miktoarm Star Polymers: Synthesis, Self-Assembly, and Study of Micelle Stability Using AF4 for Efficient Drug Delivery.

    Science.gov (United States)

    Moquin, Alexandre; Sharma, Anjali; Cui, Yiming; Lau, Anthony; Maysinger, Dusica; Kakkar, Ashok

    2015-12-01

    A simple and versatile methodology, which employs a combination of ring-opening polymerization and alkyne-azide click chemistry to synthesize amphiphilic AB3 miktoarm stars, is reported. Their aqueous self-assembly behavior was studied using dynamic light scattering, fluorescence, and asymmetrical flow field-flow fractionation (AF4). AB3 miktoarm stars form micelles which incorporate curcumin with high efficiency, and significantly reduce the viability of glioblastoma cells in spheroids. We demonstrate that AF4 is an effective technique to determine the size distribution of self-assembled structures exposed to a biological medium. The ease, with which asymmetric AB3 miktoarm polymers are constructed, provides a platform that can be widely employed to deliver a variety of lipophilic drugs. PMID:26259625

  12. An investigation of asymmetric flow features in a scaled-up driven model of the human vocal folds

    Science.gov (United States)

    Erath, Byron D.; Plesniak, Michael W.

    2010-07-01

    Flow through a driven, 7.5 times life-size vocal fold model was investigated at corresponding life-size flow rates of Q mean = 89.1 ml/s, 159.4 ml/s, and 253.0 ml/s. The flow was scaled to match physiological values for Reynolds, Strouhal, and Euler numbers. The models were driven at a life-size frequency of 94 Hz. Particle image velocimetry (PIV) data were acquired in the anterior-posterior midplane of the glottis, and the unsteady transglottal pressure drop across the vocal folds was simultaneously measured. Flow and pressure data were obtained at four discrete instances during the closing phases of the phonatory cycle for which t/T open = 0.60, 0.70, 0.80, and 0.90. The glottal jet trajectory exhibited a bimodal distribution of flow attachment between the two medial surfaces of the glottis. Vortex shedding at the trailing edge separation point generated instabilities in the shear layer, which caused large oscillations in the glottal jet orientation downstream of the glottal exit. The development of the Coanda effect during the glottal cycle was found to have minimal impact on the transglottal pressure drop, suggesting that flow orientation does not directly influence the dipole sound source. The change in transglottal pressure drop as a result of jet trajectory was less than 2% for all three investigated flow rates.

  13. Three Dimensional Separation with Spiral-Focus in a Decelerating Duct Flow (Effect of Asymmetric Inlet Boundary Layer Thickness)

    Institute of Scientific and Technical Information of China (English)

    Yoichi Kinoue; Toshiaki Setoguchi; Kenji Kaneko; Mamun Mohammad; Masahiro Inoue

    2003-01-01

    An experimental apparatus was developed to study the three dimensional separated flow with spiral-foci. The internal decelerating flow was generated by the air suction from a side wall to produce the separation on an opposite-side wall. The relation between the upstream boundary layer and the generation of spiral-foci in the separation region was observed by a tuft method. As a result, it was clarified that the spiral-focus type separation could be produced on the side wall and its behavior was closely related to the vortices supplied into the separation region from the boundary layer developing along top wall or bottom one.

  14. Double-diffusive natural convection in an asymmetric trapezoidal enclosure: unsteady behavior in the laminar and the turbulent-flow regime

    Energy Technology Data Exchange (ETDEWEB)

    Papanicolaou, E.; Belessiotis, V. [Demokritos National Center for Scientific Research, Attiki (Greece). Solar and Other Energy Systems Lab.

    2005-01-01

    In the present work the natural convective heat and mass transfer in an asymmetric, trapezoidal enclosure is studied numerically. Such a configuration is encountered in greenhouse-type solar stills, where natural convection in the enclosed humid air due to vertical temperature and concentration gradients between the saline water and the transparent cover, plays a decisive role. In this double-diffusion problem, the relative magnitude of the thermal and the concentration (or solutal) Rayleigh numbers, expressed by their ratio N is a key parameter. The two-dimensional flow equations, expressed here in a stream function-vorticity ({psi} - {omega}) formulation, along with the energy and concentration equations are solved. Due to the large values of the Rayleigh numbers encountered under realistic conditions (10{sup 7} {<=} Ra {<=} 10{sup 10}), mostly turbulent flow conditions prevail. A two-equation, low-Reynolds number turbulence model has thus been selected and a curvilinear coordinate system is employed, allowing for better matching of the computational grid to the enclosure geometry. The numerical solutions yield a multi-cellular flow field, with the number of cells depending on the Rayleigh number for a fixed Lewis number and geometry. For a positive value of N (N = 1) the solution is qualitatively similar to the case with only thermal buoyancy present (N = 0). However, for negative values (N=-1), more complex unsteady phenomena arise, having a different nature in the laminar and the turbulent flow regime, which are both investigated. Correlations for the mean convective heat and mass transfer coefficients are obtained for a wide range of Rayleigh numbers, and comparisons are made for the different values of N, showing lower values and different rate of increase with Ra for N = -1. (author)

  15. Ist and IInd elliptic solutions to the extended Grad-Shafranov-Schluter equation for asymmetric tokamak plasma with stationary flows

    International Nuclear Information System (INIS)

    The existence of poloidal flow transforms the elliptic Grad-Shafranov-Schluter equation into a system of mixed type partial differential equation (EGSS equation) and an algebraic Bernoulli's equation. The computer program for solving EGSS equations using inverse method and Fourier decomposition has been prepared. The specific test solutions in the first and second ellipticity regions have been found. (author) 3 refs., 16 figs

  16. Influence of magnetic field on peristaltic flow of a Casson fluid in an asymmetric channel: Application in crude oil refinement

    Science.gov (United States)

    Sher Akbar, Noreen

    2015-03-01

    The influence of magnetic field on peristaltic flow of a Casson fluid model is considered. The model for peristaltic literature is modelled first time. The governing coupled equations are constructed under long wavelength and low Reynold's number approximation. Exact solutions are evaluated for stream function and pressure gradient. The important findings in this study are the variation of the Hartmann number M, Casson fluid parameter ζ and amplitudes a, b, d and ϕ. The velocity field increases due to increase in Hartmann number M near the channel walls while velocity field decreases at the centre of the channel.

  17. Influence of magnetic field on peristaltic flow of a Casson fluid in an asymmetric channel: Application in crude oil refinement

    International Nuclear Information System (INIS)

    The influence of magnetic field on peristaltic flow of a Casson fluid model is considered. The model for peristaltic literature is modelled first time. The governing coupled equations are constructed under long wavelength and low Reynold's number approximation. Exact solutions are evaluated for stream function and pressure gradient. The important findings in this study are the variation of the Hartmann number M, Casson fluid parameter ζ and amplitudes a, b, d and ϕ. The velocity field increases due to increase in Hartmann number M near the channel walls while velocity field decreases at the centre of the channel. - Highlights: • The influence of magnetic field on peristaltic flow of a Casson fluid model is considered. • The model for peristaltic literature is modelled first time. • The governing coupled equations are constructed under long wavelength and low Reynold's number approximation. • Exact solutions are evaluated for stream function and pressure gradient. • The velocity field increases due to increase in Hartmann number M near the channel walls while velocity field decreases at the centre of the channel

  18. Asymmetric collider

    International Nuclear Information System (INIS)

    The study of CP violation in beauty decay is one of the key challenges facing high energy physics. Much work has not yielded a definitive answer how this study might best be performed. However, one clear conclusion is that new accelerator facilities are needed. Proposals include experiments at asymmetric electron-positron colliders and in fixed-target and collider modes at LHC and SSC. Fixed-target and collider experiments at existing accelerators, while they might succeed in a first observation of the effect, will not be adequate to study it thoroughly. Giomataris has emphasized the potential of a new approach to the study of beauty CP violation: the asymmetric proton collider. Such a collider might be realized by the construction of a small storage ring intersecting an existing or soon-to-exist large synchrotron, or by arranging collisions between a large synchrotron and its injector. An experiment at such a collider can combine the advantages of fixed-target-like spectrometer geometry, facilitating triggering, particle identification and the instrumentation of a large acceptance, while the increased √s can provide a factor > 100 increase in beauty-production cross section compared to Tevatron or HERA fixed-target. Beams crossing at a non-zero angle can provide a small interaction region, permitting a first-level decay-vertex trigger to be implemented. To achieve large √s with a large Lorentz boost and high luminosity, the most favorable venue is the high-energy booster (HEB) at the SSC Laboratory, though the CERN SPS and Fermilab Tevatron are also worth considering

  19. Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow

    Directory of Open Access Journals (Sweden)

    Hilton Helen

    2010-05-01

    Full Text Available Abstract Background Vertebrates show clear asymmetry in left-right (L-R patterning of their organs and associated vasculature. During mammalian development a cilia driven leftwards flow of liquid leads to the left-sided expression of Nodal, which in turn activates asymmetric expression of the transcription factor Pitx2. While Pitx2 asymmetry drives many aspects of asymmetric morphogenesis, it is clear from published data that additional asymmetrically expressed loci must exist. Results A L-R expression screen identified the cytoskeletally-associated gene, actin binding lim protein 1 (Ablim1, as asymmetrically expressed in both the node and left lateral plate mesoderm (LPM. LPM expression closely mirrors that of Nodal. Significantly, Ablim1 LPM asymmetry was detected in the absence of detectable Nodal. In the node, Ablim1 was initially expressed symmetrically across the entire structure, resolving to give a peri-nodal ring at the headfold stage in a flow and Pkd2-dependent manner. The peri-nodal ring of Ablim1 expression became asymmetric by the mid-headfold stage, showing stronger right than left-sided expression. Node asymmetry became more apparent as development proceeded; expression retreated in an anticlockwise direction, disappearing first from the left anterior node. Indeed, at early somite stages Ablim1 shows a unique asymmetric expression pattern, in the left lateral plate and to the right side of the node. Conclusion Left LPM Ablim1 is expressed in the absence of detectable LPM Nodal, clearly revealing existence of a Pitx2 and Nodal-independent left-sided signal in mammals. At the node, a previously unrecognised action of early nodal flow and Pkd2 activity, within the pit of the node, influences gene expression in a symmetric manner. Subsequent Ablim1 expression in the peri-nodal ring reveals a very early indication of L-R asymmetry. Ablim1 expression analysis at the node acts as an indicator of nodal flow. Together these results make

  20. Engineered Asymmetric Synthetic Vesicles

    Science.gov (United States)

    Lu, Li; Chiarot, Paul

    2013-11-01

    Synthetic vesicles are small, fluid-filled spheres that are enclosed by a bilayer of lipid molecules. They can be used as models for investigating membrane biology and as delivery vehicles for pharmaceuticals. In practice, it is difficult to simultaneously control membrane asymmetry, unilamellarity, vesicle size, vesicle-to-vesicle uniformity, and luminal content. Membrane asymmetry, where each leaflet of the bilayer is composed of different lipids, is of particular importance as it is a feature of most natural membranes. In this study, we leverage microfluidic technology to build asymmetric vesicles at high-throughput. We use the precise flow control offered by microfluidic devices to make highly uniform emulsions, with controlled internal content, that serve as templates to build the synthetic vesicles. Flow focusing, dielectrophoretic steering, and interfacial lipid self-assembly are critical procedures performed on-chip to produce the vesicles. Fluorescent and confocal microscopy are used to evaluate the vesicle characteristics.

  1. Asymmetric Ashes

    Science.gov (United States)

    2006-11-01

    that oscillate in certain directions. Reflection or scattering of light favours certain orientations of the electric and magnetic fields over others. This is why polarising sunglasses can filter out the glint of sunlight reflected off a pond. When light scatters through the expanding debris of a supernova, it retains information about the orientation of the scattering layers. If the supernova is spherically symmetric, all orientations will be present equally and will average out, so there will be no net polarisation. If, however, the gas shell is not round, a slight net polarisation will be imprinted on the light. This is what broad-band polarimetry can accomplish. If additional spectral information is available ('spectro-polarimetry'), one can determine whether the asymmetry is in the continuum light or in some spectral lines. In the case of the Type Ia supernovae, the astronomers found that the continuum polarisation is very small so that the overall shape of the explosion is crudely spherical. But the much larger polarization in strongly blue-shifted spectral lines evidences the presence, in the outer regions, of fast moving clumps with peculiar chemical composition. "Our study reveals that explosions of Type Ia supernovae are really three-dimensional phenomena," says Dietrich Baade. "The outer regions of the blast cloud is asymmetric, with different materials found in 'clumps', while the inner regions are smooth." "This study was possible because polarimetry could unfold its full strength thanks to the light-collecting power of the Very Large Telescope and the very precise calibration of the FORS instrument," he adds. The research team first spotted this asymmetry in 2003, as part of the same observational campaign (ESO PR 23/03 and ESO PR Photo 26/05). The new, more extensive results show that the degree of polarisation and, hence, the asphericity, correlates with the intrinsic brightness of the explosion. The brighter the supernova, the smoother, or less clumpy

  2. Influence of Heat Source, Thermal Radiation and Inclined Magnetic Field on Peristaltic Flow of a Hyperbolic Tangent Nanofluid in a Tapered Asymmetric Channel.

    Science.gov (United States)

    Kothandapani, Munirathinam; Prakash, Jayavel

    2014-10-31

    In the present analytic thinking, we have modeled the governing equations of a two dimensional peristaltic transport of a Hyperbolic tangent nanofluid in the presence of a heat source/sink with the combined effects of thermal radiation and inclined magnetic field in a tapered asymmetric channel. The propagation of waves on the non-uniform walls to have different amplitudes and phase but the same wave speed is produced the tapered asymmetric channel. The equations of dimensionless temperature and nanoparticle concentration are solved analytically under assumptions of long wavelength and low Reynolds number. The governing equations of momentum of a hyperbolic tangent nanofluid for the tapered asymmetric channel have also been solved analytically using the regular perturbation method. The expression for average rise in pressure has been figured using numerical integrations. The effects of various physical parameters entering into the problem are discussed numerically and graphically. The phenomenon of trapping is also investigated. Furthermore, the received results show that the maximum pressure rise gets increased in case of non-Newtonian fluid when equated with Newtonian fluid. PMID:25373110

  3. Asymmetric Wettability Directs Leidenfrost Droplets

    Energy Technology Data Exchange (ETDEWEB)

    Agapov, Rebecca L [ORNL; Boreyko, Jonathan B [ORNL; Briggs, Dayrl P [ORNL; Srijanto, Bernadeta R [ORNL; Retterer, Scott T [ORNL; Collier, Pat [ORNL; Lavrik, Nickolay V [ORNL

    2014-01-01

    Leidenfrost phenomena on nano- and microstructured surfaces are of great importance for increasing control over heat transfer in high power density systems utilizing boiling phenomena. They also provide an elegant means to direct droplet motion in a variety of recently emerging fluidic systems. Here, we report the fabrication and characterization of tilted nanopillar arrays (TNPAs) that exhibit directional Leidenfrost water droplets under dynamic conditions, namely on impact with Weber numbers 40 at T 325 C. The batch fabrication of the TNPAs was achieved by glancing-angle anisotropic reactive ion etching of a thermally dewet platinum mask, with mean pillar diameters of 100 nm and heights of 200-500 nm. In contrast to previously implemented macro- and microscopic Leidenfrost ratchets, our TNPAs induce no preferential directional movement of Leidenfrost droplets under conditions approaching steady-state film boiling, suggesting that the observed droplet directionality is not a result of asymmetric vapor flow. Using high-speed imaging, phase diagrams were constructed for the boiling behavior upon impact for droplets falling onto TNPAs, straight nanopillar arrays, and smooth silicon surfaces. The asymmetric impact and directional trajectory of droplets was exclusive to the TNPAs for impacts corresponding to the transition boiling regime, revealing that asymmetric wettability upon impact is the mechanism for the droplet directionality.

  4. The role of zonally asymmetric heating in the vertical and temporal structure of the global scale flow fields during FGGE SOP-1

    Science.gov (United States)

    Paegle, J.; Kalnay, E.; Baker, W. E.

    1981-01-01

    The global scale structure of atmospheric flow is best documented on time scales longer than a few days. Theoretical and observational studies of ultralong waves have emphasized forcing due to global scale variations of topography and surface heat flux, possibly interacting with baroclinically unstable or vertically refracting basic flows. Analyses of SOP-1 data in terms of global scale spherical harmonics is documented with emphasis upon weekly transitions.

  5. Asymmetric fuel assembly for BWR type reactor

    International Nuclear Information System (INIS)

    A coolant turning introduction member is properly extended at coolant flow channels on the side of control rod of an inner frame for supporting the insertion of a water channel. With such a constitution, the thermal margin of the fuel rods can be made uniform over the entire region of the channel box by supplying coolants uniformly for an asymmetrical fuel assembly which can effectively suppress local peaking coefficient thereby enabling to improve performances at limit power. In addition, in the asymmetrical fuel assembly, a flow vane disposed to the outer frame plate of a spacer is increased in the size at coolant flow channels on the side of the control rod. Then, sufficient amount of coolants can surely be supplied to fuel rods at coolant flow channels on the side of the control rod. (N.H.)

  6. Asymmetric-Structure Analysis of Carbon and Energy Markets

    Science.gov (United States)

    Xu, Wei; Cao, Guangxi

    2016-02-01

    This study aimed to investigate the asymmetric structure between the carbon and energy markets from two aspects of different trends (up or down) and volatility-transmission direction using asymmetric detrended cross-correlation analysis (DCCA) cross-correlation coefficient test, multifractal asymmetric DCCA (MF-ADCCA) method, asymmetric volatility-constrained correlation metric and time rate of information-flow approach. We sampled 1283 observations from January 2008 to December 2012 among pairs of carbon and energy markets for analysis. Empirical results show that the (1) asymmetric characteristic from the cross-correlation between carbon and returns in the energy markets is significant, (2) asymmetric cross-correlation between carbon and energy market price returns is persistent and multifractral and (3) volatility of the base assets of energy market returns is more influential to the base asset of the carbon market than that of the energy market.

  7. Monitoring of barley starch amylolysis by gravitational field flow fractionation and MALDI-TOF MS

    Czech Academy of Sciences Publication Activity Database

    Mazanec, Karel; Dyčka, Filip; Bobálová, Janette

    2011-01-01

    Roč. 91, č. 15 (2011), s. 2756-2761. ISSN 0022-5142 R&D Projects: GA MŠk 1M0570; GA MŠk 1M06030; GA MŠk 2B06037 Institutional research plan: CEZ:AV0Z40310501 Keywords : barley * starch * malting process Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 1.436, year: 2011

  8. Monitoring of barley starch amylolysis by gravitational field flow fractionation and MALDI-TOF/TOF MS

    Czech Academy of Sciences Publication Activity Database

    Mazanec, Karel; Bobálová, Janette

    2008-01-01

    Roč. 102, č. 15 (2008), s728-s729. ISSN 1803-2389. [Meeting on Chemistry and Life /4./. Brno, 09.09.2008-11.09.2008] R&D Projects: GA MŠk 1M0570 Institutional research plan: CEZ:AV0Z40310501 Keywords : gravitational FFF * MALDI MS * starch Subject RIV: CB - Analytical Chemistry, Separation

  9. Filter-feeding, near-field flows, and the morphologies of colonial choanoflagellates

    CERN Document Server

    Kirkegaard, Julius B

    2016-01-01

    Efficient uptake of nutrients from the environment is an important component in the fitness of all microorganisms, and its dependence on size may reveal clues to the origins of evolutionary transitions to multicellularity. Because potential benefits in uptake rates must be viewed in the context of other costs and benefits of size, such as varying predation rates and the increased metabolic costs associated with larger and more complex body plans, the uptake rate itself is not necessarily that which is optimized by evolution. Uptake rates can be strongly dependent on local organism geometry and its swimming speed, providing selective pressure for particular arrangements. Here we examine these issues for choanoflagellates, filter-feeding microorganisms that are the closest relatives of the animals. We explore the different morphological variations of the choanoflagellete $Salpingoeca~rosetta$, which can exist as a swimming cell, a sessile thecate cell, and as colonies of cells in various shapes. In the absence ...

  10. The Asymmetric Leximin Solution

    OpenAIRE

    Driesen, Bram W.

    2012-01-01

    In this article we define and characterize a class of asymmetric leximin solutions, that contains both the symmetric leximin solution of Imai[5] and the two-person asymmetric Kalai-Smorodinsky solution of Dubra [3] as special cases. Solutions in this class combine three attractive features: they are defined on the entire domain of convex n-person bargaining problems, they generally yield Pareto efficient solution outcomes, and asymmetries among bargainers are captured by a single parameter ve...

  11. Asymmetric WIMP dark matter

    OpenAIRE

    Graesser, Michael L.; Shoemaker, Ian M.; Vecchi, Luca

    2011-01-01

    In existing dark matter models with global symmetries the relic abundance of dark matter is either equal to that of anti-dark matter (thermal WIMP), or vastly larger, with essentially no remaining anti-dark matter (asymmetric dark matter). By exploring the consequences of a primordial asymmetry on the coupled dark matter and anti-dark matter Boltzmann equations we find large regions of parameter space that interpolate between these two extremes. Interestingly, this new asymmetric WIMP framewo...

  12. Ecological differentiation, lack of hybrids involving diploids, and asymmetric gene flow between polyploids in narrow contact zones of Senecio carniolicus (syn. Jacobaea carniolica, Asteraceae)

    Czech Academy of Sciences Publication Activity Database

    Hülber, K.; Sonnleitner, M.; Suda, Jan; Krejčíková, J.; Schönswetter, P.; Schneeweiss, G. M.; Winkler, M.

    2015-01-01

    Roč. 5, č. 6 (2015), s. 1224-1234. ISSN 2045-7758 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : gene flow * hybridization * polyploidy Subject RIV: EF - Botanics Impact factor: 2.320, year: 2014

  13. Effects of rotation and magnetic field on the nonlinear peristaltic flow of a second-order fluid in an asymmetric channel through a porous medium

    International Nuclear Information System (INIS)

    In this paper, the effects of both rotation and magnetic field of the peristaltic transport of a second-order fluid through a porous medium in a channel are studied analytically and computed numerically. The material is represented by the constitutive equations for a second-order fluid. Closed-form solutions under the consideration of long wavelength and low Reynolds number is presented. The analytical expressions for the pressure gradient, pressure rise, friction force, stream function, shear stress, and velocity are obtained in the physical domain. The effects of the non-dimensional wave amplitude, porosity, magnetic field, rotation, and the dimensionless time-mean flow in the wave frame are analyzed theoretically and computed numerically. Numerical results are given and illustrated graphically in each case considered. Comparison was made with the results obtained in the presence and absence of rotation, magnetic field, and porosity. The results indicate that the effects of the non-dimensional wave amplitude, porosity, magnetic field, rotation, and the dimensionless time-mean flow are very pronounced in the phenomena

  14. Ecological differentiation, lack of hybrids involving diploids, and asymmetric gene flow between polyploids in narrow contact zones of Senecio carniolicus (syn. Jacobaea carniolica, Asteraceae).

    Science.gov (United States)

    Hülber, Karl; Sonnleitner, Michaela; Suda, Jan; Krejčíková, Jana; Schönswetter, Peter; Schneeweiss, Gerald M; Winkler, Manuela

    2015-03-01

    Areas of immediate contact of different cytotypes offer a unique opportunity to study evolutionary dynamics within heteroploid species and to assess isolation mechanisms governing coexistence of cytotypes of different ploidy. The degree of reproductive isolation of cytotypes, that is, the frequency of heteroploid crosses and subsequent formation of viable and (partly) fertile hybrids, plays a crucial role for the long-term integrity of lineages in contact zones. Here, we assessed fine-scale distribution, spatial clustering, and ecological niches as well as patterns of gene flow in parental and hybrid cytotypes in zones of immediate contact of di-, tetra-, and hexaploid Senecio carniolicus (Asteraceae) in the Eastern Alps. Cytotypes were spatially separated also at the investigated microscale; the strongest spatial separation was observed for the fully interfertile tetra- and hexaploids. The three main cytotypes showed highly significant niche differences, which were, however, weaker than across their entire distribution ranges in the Eastern Alps. Individuals with intermediate ploidy levels were found neither in the diploid/tetraploid nor in the diploid/hexaploid contact zones indicating strong reproductive barriers. In contrast, pentaploid individuals were frequent in the tetraploid/hexaploid contact zone, albeit limited to a narrow strip in the immediate contact zone of their parental cytotypes. AFLP fingerprinting data revealed introgressive gene flow mediated by pentaploid hybrids from tetra- to hexaploid individuals, but not vice versa. The ecological niche of pentaploids differed significantly from that of tetraploids but not from hexaploids. PMID:25859328

  15. Asymmetric ion trap

    International Nuclear Information System (INIS)

    An ion trap having two end cap electrodes disposed asymmetrically about a center of a ring electrode is disclosed. The inner surface of the end cap electrodes are conformed to an asymmetric pair of equipotential lines of the harmonic formed by the application of voltages to the electrodes. The asymmetry of the end cap electrodes allows ejection of charged species through the closer of the two electrodes which in turn allows for simultaneously detecting anions and cations expelled from the ion trap through the use of two detectors charged with opposite polarity. 4 figs

  16. Asymmetric Wettability Directs Leidenfrost Droplets

    Science.gov (United States)

    Agapov, Rebecca; Boreyko, Jonathan; Briggs, Dayrl; Srijanto, Bernadeta; Retterer, Scott; Collier, C. Patrick; Lavrik, Nickolay

    2014-03-01

    Exploration of Leidenfrost droplets on nano- and microstructured surfaces are of great importance for increasing control over heat transfer in high power density systems using boiling phenomena. They also provide an elegant way to direct droplet motion in a variety of emerging fluidic systems. Here, we report the fabrication and characterization of tilted nanopillar arrays (TNPAs) that exhibit directional Leidenfrost water droplets under dynamic conditions. The batch fabrication of the TNPAs was achieved by glancing-angle anisotropic reactive ion etching of a thermally dewet platinum mask. In contrast to previously implemented macro- and microscopic Leidenfrost ratchets, our TNPAs induce no preferential directional movement of Leidenfrost droplets under conditions approaching steady-state film boiling. This suggests that the observed droplet directionality is not a result of asymmetric vapor flow. Phase diagrams were constructed for the boiling behavior upon droplet impact onto TNPAs, straight nanopillar arrays, and smooth silicon surfaces. Asymmetric wettability and directional trajectory of droplets was exclusive to the TNPAs for impacts corresponding to the transition boiling regime, revealing this to be the mechanism for the droplet directionality. This work was conducted at the Center for Nanophase Materials Sciences, which is sponsored at Oak Ridge National Lab by the Division of Scientific User Facilities, US Dept. of Energy.

  17. Catalytic Methods in Asymmetric Synthesis Advanced Materials, Techniques, and Applications

    CERN Document Server

    Gruttadauria, Michelangelo

    2011-01-01

    This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milesto

  18. Hodge operator and asymmetric fluid in unbounded domains

    Directory of Open Access Journals (Sweden)

    I. kondrashuk

    2009-06-01

    Full Text Available A system of equations modeling the stationary flow of an incompressible asymmetric fluid is studied for bounded domains of an arbitrary form. Based on the methods of Clifford analysis, we write the system of asymmetric fluid in the hypercomplex formulation and represent its solution in Clifford operator terms. We have significantly used Clifford algebra, and in particular the Hodge operator of the Clifford algebra to demonstrate the existence and uniqueness of the strong solution for arbitrary unbounded domains.

  19. Asymmetric Organocatalytic Cycloadditions

    DEFF Research Database (Denmark)

    Mose, Rasmus

    2016-01-01

    were pioneered by Otto Paul Hermann Diels and Kurt Alder who discovered what later became known as the Diels Alder reaction. The Diels Alder reaction is a [4+2] cycloaddition in which a π4 component reacts with a π2 component via a cyclic transition state to generate a 6 membered ring. This reaction...... reactions constitute the first organocatalytic asymmetric higher order cycloadditions and a rational for the periselectivity and stereoselectivity is provided based on experimental and computational investigations....

  20. Asymmetric extractions in orthodontics

    Directory of Open Access Journals (Sweden)

    Camilo Aquino Melgaço

    2012-04-01

    Full Text Available INTRODUCTION: Extraction decisions are extremely important in during treatment planning. In addition to the extraction decision orthodontists have to choose what tooth should be extracted for the best solution of the problem and the esthetic/functional benefit of the patient. OBJECTIVE: This article aims at reviewing the literature relating the advantages, disadvantages and clinical implications of asymmetric extractions to orthodontics. METHODS: Keywords were selected in English and Portuguese and the EndNote 9 program was used for data base search in PubMed, Web of Science (WSc and LILACS. The selected articles were case reports, original articles and prospective or retrospective case-control studies concerning asymmetrical extractions of permanent teeth for the treatment of malocclusions. CONCLUSION: According to the literature reviewed asymmetric extractions can make some specific treatment mechanics easier. Cases finished with first permanent molars in Class II or III relationship in one or both sides seem not to cause esthetic or functional problems. However, diagnosis knowledge and mechanics control are essential for treatment success.

  1. Asymmetric Evolutionary Games.

    Science.gov (United States)

    McAvoy, Alex; Hauert, Christoph

    2015-08-01

    Evolutionary game theory is a powerful framework for studying evolution in populations of interacting individuals. A common assumption in evolutionary game theory is that interactions are symmetric, which means that the players are distinguished by only their strategies. In nature, however, the microscopic interactions between players are nearly always asymmetric due to environmental effects, differing baseline characteristics, and other possible sources of heterogeneity. To model these phenomena, we introduce into evolutionary game theory two broad classes of asymmetric interactions: ecological and genotypic. Ecological asymmetry results from variation in the environments of the players, while genotypic asymmetry is a consequence of the players having differing baseline genotypes. We develop a theory of these forms of asymmetry for games in structured populations and use the classical social dilemmas, the Prisoner's Dilemma and the Snowdrift Game, for illustrations. Interestingly, asymmetric games reveal essential differences between models of genetic evolution based on reproduction and models of cultural evolution based on imitation that are not apparent in symmetric games. PMID:26308326

  2. PASSIVE CONTROL OF PARTICLE DISPERSION IN A PARTICLE-LADEN CIRCULAR JET USING ELLIPTIC CO-ANNULAR FLOW: A MEANS FOR IMPROVING UTILIZATION AND EMISSION REDUCTIONS IN PULVERIZED COAL BURNER

    Energy Technology Data Exchange (ETDEWEB)

    Ahsan R. Choudhuri

    2003-06-01

    A passive control technology utilizing elliptic co-flow to control the particle flinging and particle dispersion in a particle (coal)-laden flow was investigated using experimental and numerical techniques. Preferential concentration of particles occurs in particle-laden jets used in pulverized coal burner and causes uncontrollable NO{sub x} formation due to inhomogeneous local stoichiometry. This particular project was aimed at characterizing the near-field flow behavior of elliptic coaxial jets. The knowledge gained from the project will serve as the basis of further investigation on fluid-particle interactions in an asymmetric coaxial jet flow-field and thus is important to improve the design of pulverized coal burners where non-homogeneity of particle concentration causes increased NO{sub x} formation.

  3. Facilitated Asymmetric Exclusion

    OpenAIRE

    Gabel, Alan; Krapivsky, P. L.; Redner, S.

    2010-01-01

    We introduce a class of facilitated asymmetric exclusion processes in which particles are pushed by neighbors from behind. For the simplest version in which a particle can hop to its vacant right neighbor only if its left neighbor is occupied, we determine the steady state current and the distribution of cluster sizes on a ring. We show that an initial density downstep develops into a rarefaction wave that can have a jump discontinuity at the leading edge, while an upstep results in a shock w...

  4. Asymmetric synthesis v.4

    CERN Document Server

    Morrison, James

    1984-01-01

    Asymmetric Synthesis, Volume 4: The Chiral Carbon Pool and Chiral Sulfur, Nitrogen, Phosphorus, and Silicon Centers describes the practical methods of obtaining chiral fragments. Divided into five chapters, this book specifically examines initial chiral transmission and extension. The opening chapter describes the so-called chiral carbon pool, the readily available chiral carbon fragments used as building blocks in synthesis. This chapter also provides a list of 375 chiral building blocks, along with their commercial sources, approximate prices, and methods of synthesis. Schemes involving

  5. Métodos heurísticos construtivos para redução do estoque em processo em ambientes de produção flow shop híbridos com tempos de setup dependentes da sequência Constructive heuristics methods to minimizing work in process in environment production hybrid flow shop with asymmetric sequence dependent setup times

    Directory of Open Access Journals (Sweden)

    Márcia de Fátima Morais

    2010-01-01

    Full Text Available Este artigo apresenta uma investigação sobre o problema de programação da produção em ambientes flow shop com múltiplas máquinas (híbridos e tempos de preparação (setup das máquinas assimétricos e dependentes da sequência, e propõe métodos heurísticos construtivos para a minimização do tempo médio de fluxo (Mean Flow Time, que objetiva uma resposta rápida à demanda e à redução do estoque em processamento. Os algoritmos propostos foram comparados entre si, uma vez que nenhum método de solução para o problema investigado foi encontrado na literatura. Um estudo da influência da relação entre as ordens de grandeza dos tempos de processamento das tarefas e de preparação das máquinas em cada método de solução, bem como a influência do procedimento de programação adotado, foi efetuado com o intuito de avaliar o desempenho dos métodosThis paper presents an investigation about the hybrid flow shop problem with asymmetric sequence dependent setup times and proposes constructive heuristic methods to minimize the mean flow time aiming at fast demand response and work in process reduction. The proposed heuristic methods were compared among themselves since no constructive heuristic method was found in the literature on the scheduling problem considered in this work. A study on the influence of the relation between the orders of magnitude of processing and setup time for each method was carried out. The influence of the scheduling procedure adopted was investigated to assess the performance of the methods use

  6. Asymmetric quantum cloning machines

    International Nuclear Information System (INIS)

    A family of asymmetric cloning machines for quantum bits and N-dimensional quantum states is introduced. These machines produce two approximate copies of a single quantum state that emerge from two distinct channels. In particular, an asymmetric Pauli cloning machine is defined that makes two imperfect copies of a quantum bit, while the overall input-to-output operation for each copy is a Pauli channel. A no-cloning inequality is derived, characterizing the impossibility of copying imposed by quantum mechanics. If p and p' are the probabilities of the depolarizing channels associated with the two outputs, the domain in (√p,√p')-space located inside a particular ellipse representing close-to-perfect cloning is forbidden. This ellipse tends to a circle when copying an N-dimensional state with N→∞, which has a simple semi-classical interpretation. The symmetric Pauli cloning machines are then used to provide an upper bound on the quantum capacity of the Pauli channel of probabilities px, py and pz. The capacity is proven to be vanishing if (√px, √py, √pz) lies outside an ellipsoid whose pole coincides with the depolarizing channel that underlies the universal cloning machine. Finally, the tradeoff between the quality of the two copies is shown to result from a complementarity akin to Heisenberg uncertainty principle. (author)

  7. Asymmetric inclusion process

    Science.gov (United States)

    Reuveni, Shlomi; Eliazar, Iddo; Yechiali, Uri

    2011-10-01

    We introduce and explore the asymmetric inclusion process (ASIP), an exactly solvable bosonic counterpart of the fermionic asymmetric exclusion process (ASEP). In both processes, random events cause particles to propagate unidirectionally along a one-dimensional lattice of n sites. In the ASEP, particles are subject to exclusion interactions, whereas in the ASIP, particles are subject to inclusion interactions that coalesce them into inseparable clusters. We study the dynamics of the ASIP, derive evolution equations for the mean and probability generating function (PGF) of the sites’ occupancy vector, obtain explicit results for the above mean at steady state, and describe an iterative scheme for the computation of the PGF at steady state. We further obtain explicit results for the load distribution in steady state, with the load being the total number of particles present in all lattice sites. Finally, we address the problem of load optimization, and solve it under various criteria. The ASIP model establishes bridges between statistical physics and queueing theory as it represents a tandem array of queueing systems with (unlimited) batch service, and a tandem array of growth-collapse processes.

  8. Alternative Asymmetric Stochastic Volatility Models

    NARCIS (Netherlands)

    M. Asai (Manabu); M.J. McAleer (Michael)

    2010-01-01

    textabstractThe stochastic volatility model usually incorporates asymmetric effects by introducing the negative correlation between the innovations in returns and volatility. In this paper, we propose a new asymmetric stochastic volatility model, based on the leverage and size effects. The model is

  9. Asymmetric black dyonic holes

    Directory of Open Access Journals (Sweden)

    I. Cabrera-Munguia

    2015-04-01

    Full Text Available A 6-parametric asymptotically flat exact solution, describing a two-body system of asymmetric black dyons, is studied. The system consists of two unequal counterrotating Kerr–Newman black holes, endowed with electric and magnetic charges which are equal but opposite in sign, separated by a massless strut. The Smarr formula is generalized in order to take into account their contribution to the mass. The expressions for the horizon half-length parameters σ1 and σ2, as functions of the Komar parameters and of the coordinate distance, are displayed, and the thermodynamic properties of the two-body system are studied. Furthermore, the seven physical parameters satisfy a simple algebraic relation which can be understood as a dynamical scenario, in which the physical properties of one body are affected by the ones of the other body.

  10. Asymmetric twin Dark Matter

    International Nuclear Information System (INIS)

    We study a natural implementation of Asymmetric Dark Matter in Twin Higgs models. The mirroring of the Standard Model strong sector suggests that a twin baryon with mass around 5 GeV is a natural Dark Matter candidate once a twin baryon number asymmetry comparable to the SM asymmetry is generated. We explore twin baryon Dark Matter in two different scenarios, one with minimal content in the twin sector and one with a complete copy of the SM, including a light twin photon. The essential requirements for successful thermal history are presented, and in doing so we address some of the cosmological issues common to many Twin Higgs models. The required interactions we introduce predict signatures at direct detection experiments and at the LHC

  11. Organizing for Asymmetric Collaboration

    DEFF Research Database (Denmark)

    Nielsen, Jørn Flohr; Sørensen, Henrik B.

    meet each other. On the contrary, we assume that asymmetry is both important and normal; moreover, asymmetry should be considered to be more complex than economists indicate with their concept of asymmetric information. Thus, the aim of the paper is to explore how asymmetries related to partners......  The vision of new organizational forms consists of less-organized networks and alliances between organizations, in which collaborative capabilities are assumed to be crucial (Miles et al., 2005). The path to such new forms may go through fragile cooperative efforts. Despite the good will of many......' different motives and different situational factors appear in an interorganizational setting. We classify interfaces according to the symmetry/asymmetry in the respective parent organizations' resources, commitment, and control of representatives and indicate how  classification schemes can be used to...

  12. Annihilating Asymmetric Dark Matter

    CERN Document Server

    Bell, Nicole F; Shoemaker, Ian M

    2014-01-01

    The relic abundance of particle and antiparticle dark matter (DM) need not be vastly different in thermal asymmetric dark matter (ADM) models. By considering the effect of a primordial asymmetry on the thermal Boltzmann evolution of coupled DM and anti-DM, we derive the requisite annihilation cross section. This is used in conjunction with CMB and Fermi-LAT gamma-ray data to impose a limit on the number density of anti-DM particles surviving thermal freeze-out. When the extended gamma-ray emission from the Galactic Center is reanalyzed in a thermal ADM framework, we find that annihilation into $\\tau$ leptons prefer anti-DM number densities 1-4$\\%$ that of DM while the $b$-quark channel prefers 50-100$\\%$.

  13. Flow

    DEFF Research Database (Denmark)

    2009-01-01

    Flow er en positiv, koncentreret tilstand, hvor al opmærksomhed er samlet om en bestemt aktivitet, som er så krævende og engagerende, at man må anvende mange mentale ressourcer for at klare den. Tidsfornemmelsen forsvinder, og man glemmer sig selv. 'Flow' er den første af en række udsendelser om...

  14. Analysis of carbohydrates isolated from Norway spruce needles by asymmetrical FlFFF

    Czech Academy of Sciences Publication Activity Database

    Cabálková, Jana; Chmelík, Josef; Wahlund, K. G.

    Brno : Ústav analytické chemie AV ČR, 2005. P28. [FFF 2005. International Symposium on Field- Flow Fractionation. 28.08.2005-30.08.2005, Brno] R&D Projects: GA ČR GA526/03/1182 Keywords : carbohydrates * Norway spruce * AsFlFFF Subject RIV: CB - Analytical Chemistry, Separation

  15. Flow

    DEFF Research Database (Denmark)

    Knoop, Hans Henrik

    2006-01-01

    FLOW. Orden i hovedet på den fede måde Oplevelsesmæssigt er flow-tilstanden kendetegnet ved at man er fuldstændig involveret, fokuseret og koncentreret; at man oplever stor indre klarhed ved at vide hvad der skal gøres, og i hvilket omfang det lykkes; at man ved at det er muligt at løse opgaven...

  16. Metal rolling - Asymmetrical rolling process

    Science.gov (United States)

    Alexa, V.; Raţiu, S.; Kiss, I.

    2016-02-01

    The development of theory and practice related to the asymmetric longitudinal rolling process is based on the general theory of metalworking by pressure and symmetric rolling theory, to which a large number of scientists brought their contribution. The rolling of metal materials was a serious problem throughout history, either economically or technically, because the plating technologies enabled the consumption of raw materials (scarce and expensive) to be reduced, while improving the mechanical properties. Knowing the force parameters related to asymmetric rolling leads to the optimization of energy and raw material consumption. This paper presents data on symmetric rolling process, in order to comparatively highlight the particularities of the asymmetric process.

  17. Multi-dimensional thermalhydraulic analysis for SMART asymmetric behavior

    International Nuclear Information System (INIS)

    The effects of the asymmetric flow/temperature distributions which are expected to occur in case of one main coolant pump(MCP) trip or steam generator(SG) one section isolation in SMART are analyzed using the best-estimate multi-dimensional thermalhydraulic system analysis code MARS/SMR. In both cases the assessment of thermal margin in the core is necessary to assure continuous reactor operation at 75% power level following the transient. In particular, SG one section isolation is useful for the leakage at secondary feedwater/steam pipes or steam generator tubes. In the case of one MCP trip, despite of reverse flow at the tripped pump, no asymmetric behavior at the downcomer annulus does appear due to well-mixing at the MCP discharge. In the case of SG one section isolation, the asymmetric behavior by nonhomogeneous heat transfer through the steam generator is predicted significant at the downocmer annulus but most of the asymmetric behavior is diminished by well-mixing at the core inlet. Therefore it is assured that the reactor operation at 75% power level is possible, since the effect of the asymmetric behavior on the core thermal margin is negligible

  18. Asymmetric Gepner Models (Revisited)

    CERN Document Server

    Gato-Rivera, B

    2010-01-01

    We reconsider a class of heterotic string theories studied in 1989, based on tensor products of N=2 minimal models with asymmetric simple current invariants. We extend this analysis from (2,2) and (1,2) spectra to (0,2) spectra with SO(10) broken to the Standard Model. In the latter case the spectrum must contain fractionally charged particles. We find that in nearly all cases at least some of them are massless. However, we identify a large subclass where the fractional charges are at worst half-integer, and often vector-like. The number of families is very often reduced in comparison to the 1989 results, but there are no new tensor combinations yielding three families. All tensor combinations turn out to fall into two classes: those where the number of families is always divisible by three, and those where it is never divisible by three. We find an empirical rule to determine the class, which appears to extend beyond minimal N=2 tensor products. We observe that distributions of physical quantities such as th...

  19. Magnetically Modified Asymmetric Supercapacitors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project is for the development of an asymmetric supercapacitor that will have improved energy density and cycle...

  20. Active Matter on Asymmetric Substrates

    OpenAIRE

    Reichhardt, C. J. Olson; Drocco, J.; Mai, T.; Wan, M. B.; Reichhardt, C.

    2011-01-01

    For collections of particles in a thermal bath interacting with an asymmetric substrate, it is possible for a ratchet effect to occur where the particles undergo a net dc motion in response to an ac forcing. Ratchet effects have been demonstrated in a variety of systems including colloids as well as magnetic vortices in type-II superconductors. Here we examine the case of active matter or self-driven particles interacting with asymmetric substrates. Active matter systems include self-motile c...

  1. Mobile Termination with Asymmetric Networks

    OpenAIRE

    Dewenter, Ralf; Haucap, Justus

    2003-01-01

    This paper examines mobile termination fees and their regulation when networks are asymmetric in size. It is demonstrated that with consumer ignorance about the exact termination rates (a) a mobile network?s termination rate is the higher the smaller the network?s size (as measured through its subscriber base) and (b) asymmetric regulation of only the larger operators in a market will, ce-teris paribus, induce the smaller operators to increase their termination rates. The results are supporte...

  2. Multicatalyst system in asymmetric catalysis

    CERN Document Server

    Zhou, Jian

    2014-01-01

    This book introduces multi-catalyst systems by describing their mechanism and advantages in asymmetric catalysis.  Helps organic chemists perform more efficient catalysis with step-by-step methods  Overviews new concepts and progress for greener and economic catalytic reactions  Covers topics of interest in asymmetric catalysis including bifunctional catalysis, cooperative catalysis, multimetallic catalysis, and novel tandem reactions   Has applications for pharmaceuticals, agrochemicals, materials, and flavour and fragrance

  3. Asymmetric Dark Matter from Leptogenesis

    OpenAIRE

    Falkowski, Adam; Ruderman, Joshua T.; Volansky, Tomer

    2011-01-01

    We present a new realization of asymmetric dark matter in which the dark matter and lepton asymmetries are generated simultaneously through two-sector leptogenesis. The right-handed neutrinos couple both to the Standard Model and to a hidden sector where the dark matter resides. This framework explains the lepton asymmetry, dark matter abundance and neutrino masses all at once. In contrast to previous realizations of asymmetric dark matter, the model allows for a wide range of dark matter mas...

  4. Asymmetric Gepner models (revisited)

    Energy Technology Data Exchange (ETDEWEB)

    Gato-Rivera, B. [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands)] [Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain); Schellekens, A.N., E-mail: t58@nikhef.n [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands)] [Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain)] [IMAPP, Radboud Universiteit, Nijmegen (Netherlands)

    2010-12-11

    We reconsider a class of heterotic string theories studied in 1989, based on tensor products of N=2 minimal models with asymmetric simple current invariants. We extend this analysis from (2,2) and (1,2) spectra to (0,2) spectra with SO(10) broken to the Standard Model. In the latter case the spectrum must contain fractionally charged particles. We find that in nearly all cases at least some of them are massless. However, we identify a large subclass where the fractional charges are at worst half-integer, and often vector-like. The number of families is very often reduced in comparison to the 1989 results, but there are no new tensor combinations yielding three families. All tensor combinations turn out to fall into two classes: those where the number of families is always divisible by three, and those where it is never divisible by three. We find an empirical rule to determine the class, which appears to extend beyond minimal N=2 tensor products. We observe that distributions of physical quantities such as the number of families, singlets and mirrors have an interesting tendency towards smaller values as the gauge groups approaches the Standard Model. We compare our results with an analogous class of free fermionic models. This displays similar features, but with less resolution. Finally we present a complete scan of the three family models based on the triply-exceptional combination (1,16{sup *},16{sup *},16{sup *}) identified originally by Gepner. We find 1220 distinct three family spectra in this case, forming 610 mirror pairs. About half of them have the gauge group SU(3)xSU(2){sub L}xSU(2){sub R}xU(1){sup 5}, the theoretical minimum, and many others are trinification models.

  5. Salt supply to and significance of asymmetric salt diapirs

    DEFF Research Database (Denmark)

    Koyi, H.; Burliga, S.; Chemia, Zurab

    2012-01-01

    Salt diapirs can be asymmetric both internally and externally reflecting their evolution history. As such, this asymmetry bear a significant amount of information about the differential loading (± lateral forces) and in turn the salt supply that have shaped the diapir. In two dimensions, In this...... southeastern overhang due to salt extrusion during Middle Cretaceous followed by its burial in Tertiary. This external asymmetry is also reflected in the internal configuration of the diapir which shows different rates of salt flow on the two halves of the structure. The asymmetric external and internal...

  6. Rectification of motion in nonlinear media with asymmetric random drive

    International Nuclear Information System (INIS)

    We consider moving particles in media with nonlinear friction and drive them by an asymmetric dichotomic Markov process. Due to different energy dissipations, during the forward and backward stroke, we obtain a mean non-vanishing directed flow of the particles. Starting with the stationary velocity distribution, we calculate the stationary current of particles, the variance and the relative variance in dependence on the degree of nonlinearity of the friction, on the asymmetry and for different strengths of friction. In two dimensions the particle performs diffusional motion, if in addition the direction of the asymmetric drive changes stochastically.

  7. Asymmetric Magnetic Reconnection in Weakly Ionized Chromospheric Plasmas

    CERN Document Server

    Murphy, Nicholas A

    2015-01-01

    Realistic models of magnetic reconnection in the solar chromosphere must take into account that the plasma is partially ionized and that plasma conditions within any two magnetic flux bundles undergoing reconnection may not be the same. Asymmetric reconnection in the chromosphere may occur when newly emerged flux interacts with pre-existing, overlying flux. We present 2.5D simulations of asymmetric reconnection in weakly ionized, reacting plasmas where the magnetic field strengths, ion and neutral densities, and temperatures are different in each upstream region. The plasma and neutral components are evolved separately to allow non-equilibrium ionization. As in previous simulations of chromospheric reconnection, the current sheet thins to the scale of the neutral-ion mean free path and the ion and neutral outflows are strongly coupled. However, the ion and neutral inflows are asymmetrically decoupled. In cases with magnetic asymmetry, a net flow of neutrals through the current sheet from the weak field (high ...

  8. Detection and characterization of nanoparticles by field flow fractionation (FFF) using multiangle light scattering (MALS) and ICPMS

    International Nuclear Information System (INIS)

    Full text: Exposure to engineered nanoparticles (ENPs) via food may lead to adverse health effects in humans. Metrics relevant for evaluation of toxicity of ENPs include their size distribution, agglomeration state, solubility and elemental composition. A FFF was used to size separate clays, silver, gold, selenium and GdatC82OH16 ENPs. Their radii were determined on-line by MALS and their elemental profile by ICPMS. These methods were applied for quality assurance of the long-term stability of suspensions of Ag and Se. A multitude of detection techniques, including electron microscopic imaging, are needed for future studies of ENPs in biological materials. (author)

  9. Chiral magnetic microspheres purified by centrifugal field flow fractionation and microspheres magnetic chiral chromatography for benzoin racemate separation

    OpenAIRE

    Tian, Ailin; Qi, Jing; Liu, Yating; Wang, Fengkang; Ito, Yoichiro; Wei, Yun

    2013-01-01

    Separation of enantiomers still remains a challenge due to their identical physical and chemical properties in a chiral environment, and the research on specific chiral selector along with separation techniques continues to be conducted to resolve individual enantiomers. In our laboratory the promising magnetic chiral microspheres Fe3O4@SiO2@cellulose-2, 3-bis (3, 5-dimethylphenylcarbamate) have been developed to facilitate the resolution using both its magnetic property and chiral recognitio...

  10. Hydroxamic acids in asymmetric synthesis.

    Science.gov (United States)

    Li, Zhi; Yamamoto, Hisashi

    2013-02-19

    Metal-catalyzed stereoselective reactions are a central theme in organic chemistry research. In these reactions, the stereoselection is achieved predominantly by introducing chiral ligands at the metal catalyst's center. For decades, researchers have sought better chiral ligands for asymmetric catalysis and have made great progress. Nevertheless, to achieve optimal stereoselectivity and to catalyze new reactions, new chiral ligands are needed. Because of their high metal affinity, hydroxamic acids play major roles across a broad spectrum of fields from biochemistry to metal extraction. Dr. K. Barry Sharpless first revealed their potential as chiral ligands for asymmetric synthesis in 1977: He published the chiral vanadium-hydroxamic-acid-catalyzed, enantioselective epoxidation of allylic alcohols before his discovery of Sharpless asymmetric epoxidation, which uses the titanium-tartrate complex as the chiral reagent. However, researchers have reported few highly enantioselective reactions using metal-hydroxamic acid as catalysts since then. This Account summarizes our research on metal-catalyzed asymmetric epoxidation using hydroxamic acids as chiral ligands. We designed and synthesized a series of new hydroxamic acids, most notably the C2-symmetric bis-hydroxamic acid (BHA) family. V-BHA-catalyzed epoxidation of allylic and homoallylic alcohols achieved higher activity and stereoselectivity than Sharpless asymmetric epoxidation in many cases. Changing the metal species led to a series of unprecedented asymmetric epoxidation reactions, such as (i) single olefins and sulfides with Mo-BHA, (ii) homoallylic and bishomoallylic alcohols with Zr- and Hf-BHA, and (iii) N-alkenyl sulfonamides and N-sulfonyl imines with Hf-BHA. These reactions produce uniquely functionalized chiral epoxides with good yields and enantioselectivities. PMID:23157425

  11. Incompressibility of asymmetric nuclear matter

    OpenAIRE

    Chen, Lie-Wen; Cai, Bao-Jun; Shen, Chun; Ko, Che Ming; Xu, Jun; Li, Bao-An(Department of Physics and Astronomy, Texas A&M University-Commerce, Commerce, TX, 75429-3011, USA)

    2009-01-01

    The incompressibility $K_sat(\\delta)$ of isospin asymmetric nuclear matter at its saturation density. Our results show that in the expansion of $K_sat(\\delta)$ in powers of isospin asymmetry $\\delta$, i.e., $K_sat(\\delta )$=K_{0}+K_{sat,2}\\delta^{2}+K_{sat,4}\\delta^{4}+O(\\delta^{6})$, the magnitude of the 4th-order K_{sat,4} parameter is generally small. The 2nd-order K_{sat,2} parameter thus essentially characterizes the isospin dependence of the incompressibility of asymmetric nuclear matte...

  12. Asymmetric interference in molecular photoprocesses

    International Nuclear Information System (INIS)

    For the first time, the Coulomb continuum effects in asymmetric molecular interference have been studied analytically in photoionization, photorecombination, bremsstrahlung and Compton ionization. Simple, closed-form factors describe the interference not only in monochromatic photoprocesses, but also in the continuous photoelectron spectra generated by attosecond x-ray pulses with a frequency-dependent phase and broad bandwidth. Using HeH2+ molecular ion as an example, we show how the plane wave interference pattern is strongly modified by the two-centre Coulomb continuum. Asymmetric Coulomb continuum introduces qualitative changes in a photoionization process

  13. Asymmetric Baxter-King filter

    OpenAIRE

    Buss, Ginters

    2011-01-01

    The paper proposes an extension of the symmetric Baxter-King band pass filter to an asymmetric Baxter-King filter. The optimal correction scheme of the ideal filter weights is the same as in the symmetric version, i.e, cut the ideal filter at the appropriate length and add a constant to all filter weights to ensure zero weight on zero frequency. Since the symmetric Baxter-King filter is unable to extract the desired signal at the very ends of the series, the extension to an asymmetric filter...

  14. Forces between asymmetric polymer brushes

    OpenAIRE

    Shim, D.F.K.; Cates, M. E.

    1990-01-01

    We study the equilibrium compression of asymmetric polymer brushes grafted on flat plates, under athermal and theta solvent conditions, using a lattice self-consistent field (SCF) approach. We find that the separation d between two plates coated asymmetrically with brushes of type 1 and 2, as a function of the force F, obeys the "bisection rule", d(F) = (d1(F) + d 2(F)) /2 where d1(F)and d 2(F) are the corresponding separations for the symmetric brushes of type 1 and 2 respectively.The bisect...

  15. Research on asymmetric "Jerusalem" unit

    Institute of Scientific and Technical Information of China (English)

    Jun Lu; Jianbo Wang

    2009-01-01

    An asymmetric Jerusalem unit and the frequency selective surface(FSS)structure composed of such units are designed.The transmittance of the designed FSS structure is calculated by mode-matching method and compared with the test results.The comparison results show that the FSS center frequency of the asymmetric structure unit drifts little with the variation of the incident angles of the electromagnetic waves and keeps relatively stable.The research offers a new choice for the application of FSS under the large scanning angle of electromagnetic waves.

  16. Continuous microfluidic fabrication of synthetic asymmetric vesicles.

    Science.gov (United States)

    Lu, Li; Schertzer, Jeffrey W; Chiarot, Paul R

    2015-09-01

    We report on a novel microfluidic strategy for the continuous fabrication of monodisperse asymmetric vesicles with customized membrane composition, size, and luminal content. The microfluidic device encompasses a triangular post region and two flow-focusing regions. The major steps involved in the vesicle fabrication process include: (1) forming highly uniform water emulsions in an oil/inner-leaflet-lipid solution, (2) replacing the inner-leaflet-lipid solution with an outer-leaflet-lipid solution inside the microchannel network, (3) forming water-in-oil-in-water double emulsions, and (4) extracting excess oil/outer-leaflet-lipid solution from the double emulsions. Bilayer membrane asymmetry and unilamellarity are evaluated using a fluorescence quenching assay and a transmembrane protein insertion assay, respectively. Our approach addresses many of the deficiencies found in existing technologies for building vesicles, and yields strong membrane asymmetry. The ability to create and sustain membrane asymmetry is an important feature, as it is a characteristic of nearly all natural membranes. Over 80% of the vesicles remain stable for at least 6 weeks and the membrane asymmetry is maintained for over 30 hours. The asymmetric vesicles built using this strategy are collected off-chip and hold the potential to be used as model systems in membrane biology or as vehicles for drug delivery. PMID:26220822

  17. Asymmetric Modeling of the Industrial Heavy Water Plant (PIAP)

    International Nuclear Information System (INIS)

    Software of asymmetric stationary simulation for the Industrial Heavy Water Plant (PIAP) was developed, based on an existing symmetric simulator (Brigitte 2.0).This software allows to turn off some of the isotopic enrichment twin units present in the plant and to simulate them asymmetrically, in other words, with different selection of parameters between twins.Other incorporations were done, such as passing flows between units and entering flows in strategic points of the plant.The iterative system in which the symmetric simulator is based was insufficient to develop the asymmetric simulator, so the system was modeled according to an implicit scheme for the units that form the simulator.This type of resolution resulted in a simulator that supports a big range of boundary conditions and internal parameters.Moreover, the time of calculus is short (∼3 minutes), making it actually useful.The asymmetric simulator is at the PIAP now, for its study and validation. It shows expected tendencies and results according to the symmetric simulator already validated

  18. Asymmetric exchange in flocks

    CERN Document Server

    Dadhichi, Lokrshi Prawar; Maitra, Ananyo; Ramaswamy, Sriram

    2016-01-01

    As the constituents of a flock are polar, one expects a fore-aft asymmetry in their interactions. We show here that the resulting antisymmetric part of the "exchange coupling" between a bird and its neighbours, if large enough, destabilizes the flock through spontaneous turning of the birds. The same asymmetry also yields a natural mechanism for a difference between the speed of advection of information along the flock and the speed of the flock itself. We show that the absence of detailed balance, and not merely the breaking of Galilean invariance, is responsible for this difference. We delineate the conditions on parameters and wavenumber for the existence of the turning instability. Lastly we present an alternative perspective based on flow-alignment effects in an active liquid crystal with turning inertia in contact with a momentum sink.

  19. JET and COMPASS asymmetrical disruptions

    Czech Academy of Sciences Publication Activity Database

    Gerasimov, S.N.; Abreu, P.; Baruzzo, M.; Drozdov, V.; Dvornova, A.; Havlíček, Josef; Hender, T.C.; Hronová-Bilyková, Olena; Kruezi, U.; Li, X.; Markovič, Tomáš; Pánek, Radomír; Rubinacci, G.; Tsalas, M.; Ventre, S.; Villone, F.; Zakharov, L.E.

    2015-01-01

    Roč. 55, č. 11 (2015), s. 113006-113006. ISSN 0029-5515 R&D Projects: GA MŠk(CZ) LM2011021 Institutional support: RVO:61389021 Keywords : tokamak * asymmetrical disruption * JET * COMPASS Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 3.062, year: 2014

  20. Synthesis of Asymmetric Propanetriol Analogues

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    From natural tartaric acid, (R)-2-benzyloxy-3-(2-tetrahydropyranyloxy) propanol 3 was designed and synthesized, and (R)-2-benzyloxy-3-(4-methoxybenzyloxy) propanol 7 was prepared in a new method. They can be used as chiral synthons of lysophosphatidic acid and other compounds with asymmetric propanetriol backbone.

  1. Asymmetrical Switch Costs in Children

    Science.gov (United States)

    Ellefson, Michelle R.; Shapiron, Laura R.; Chater, Nick

    2006-01-01

    Switching between tasks produces decreases in performance as compared to repeating the same task. Asymmetrical switch costs occur when switching between two tasks of unequal difficulty. This asymmetry occurs because the cost is greater when switching to the less difficult task than when switching to the more difficult task. Various theories about…

  2. Asymmetric Synthesis via Chiral Aziridines

    DEFF Research Database (Denmark)

    Tanner, David Ackland; Harden, Adrian; Wyatt, Paul; Andersson, Pher G.; Johansson, Fredrik

    1996-01-01

    A series of chiral bis(aziridines) has been synthesised and evaluated as chelating ligands for a variety of asymmetric transformations mediated by metals [Os (dihydroxylation), Pd (allylic alkylation) Cu (cyclopropanation and aziridination, Li (1,2-addition of organolithiums to imines)]. In the...

  3. Asymmetric exclusion processes with shuffled dynamics

    International Nuclear Information System (INIS)

    The asymmetric simple exclusion process (ASEP) with periodic boundary conditions is investigated for shuffled dynamics. In this type of update, in each discrete timestep the particles are updated in a random sequence. Such an update is important for several applications, e.g., for certain models of pedestrian flow in two dimensions. For the ASEP with shuffled dynamics and a related truncated process exact results are obtained for deterministic motion (p = 1). Since the shuffled dynamics is intrinsically stochastic, also this case is nontrivial. For the case of stochastic motion (0 < p < 1) it is shown that, in contrast to all other updates studied previously, the ASEP with shuffled update does not have a product measure steady state. Approximative formulae for the steady-state distribution and fundamental diagram are derived that are in very good agreement with simulation data

  4. The role of zonally asymmetric heating in the vertical and temporal structure of the global scale flow fields during FGGE SOP-1. [First Global Atmospheric Research Program Global Experiment (FGGE); Special Observing Period (SOP)

    Science.gov (United States)

    Paegle, J.; Kalnay-Rivas, E.; Baker, W. E.

    1981-01-01

    By examining the vertical structure of the low order spherical harmonics of the divergence and vorticity fields, the relative contribution of tropical and monsoonal circulations upon the global wind fields was estimated. This indicates that the overall flow over North America and the Pacific between January and February is quite distinct both in the lower and upper troposphere. In these longitudes there is a stronger tropical overturning and subtropical jet stream in January than February. The divergent flow reversed between 850 and 200 mb. Poleward rotational flow at upper levels is associated with an equatorward rotational flow at low levels. This suggests that the monsoon and other tropical circulations project more amplitude upon low order (global scale) representations of the flow than do the typical midlatitude circulations and that their structures show conspicuous changes on a time scale of a week or less.

  5. Selfhealing of asymmetric Bessel-like modes

    DEFF Research Database (Denmark)

    Israelsen, Stine Møller; Rishøj, Lars Søgaard; Rottwitt, Karsten

    2014-01-01

    We numerically investigate asymmetric Bessel-like modes in an aircladding fiber. The selfhealing ability of asymmetric Bessel-like modes is demonstrated and quantified including the angular dependency of this ability.......We numerically investigate asymmetric Bessel-like modes in an aircladding fiber. The selfhealing ability of asymmetric Bessel-like modes is demonstrated and quantified including the angular dependency of this ability....

  6. A computational study of asymmetric glottal jet deflection during phonation.

    Science.gov (United States)

    Zheng, X; Mittal, R; Bielamowicz, S

    2011-04-01

    Two-dimensional numerical simulations are used to explore the mechanism for asymmetric deflection of the glottal jet during phonation. The model employs the full Navier-Stokes equations for the flow but a simple laryngeal geometry and vocal-fold motion. The study focuses on the effect of Reynolds number and glottal opening angle with a particular emphasis on examining the importance of the so-called "Coanda effect" in jet deflection. The study indicates that the glottal opening angle has no substantial effect on glottal jet deflection. Deflection in the glottal jet is always preceded by large-scale asymmetry in the downstream portion of the glottal jet. A detailed analysis of the velocity and vorticity fields shows that these downstream asymmetric vortex structures induce a flow at the glottal exit which is the primary driver for glottal jet deflection. PMID:21476669

  7. Bile Salt Micelles and Phospholipid Vesicles Present in Simulated and Human Intestinal Fluids

    DEFF Research Database (Denmark)

    Elvang, Philipp A; Hinna, Askell H; Brouwers, Joachim; Hens, Bart; Augustijns, Patrick; Brandl, Martin

    2016-01-01

    apply asymmetrical flow field-flow fractionation (AF4) in combination with multiangle laser light scattering in an attempt to reveal coexistence of colloidal particles in both artificial and aspirated HIFs and to determine their sizes. Asymmetrical flow field-flow fractionation/multiangle laser light...

  8. Asymmetric coherent transmission for single particle diode and gyroscope

    OpenAIRE

    Yang, S.; Song, Z; Sun, C. P.

    2009-01-01

    We study the single particle scattering process in a coherent multi-site system consisting of a tight-binding ring threaded by an Aharonov-Bohm flux and several attaching leads. The asymmetric behavior of scattering matrix is discovered analytically in the framework of both Bethe Ansatz and Green's function formalism. It is found that, under certain conditions, a three-site electronic system can behave analogous to a perfect semiconductor diode where current flows only in one direction. The g...

  9. Cyclodextrins in Asymmetric and Stereospecific Synthesis

    Directory of Open Access Journals (Sweden)

    Fliur Macaev

    2015-09-01

    Full Text Available Since their discovery, cyclodextrins have widely been used as green and easily available alternatives to promoters or catalysts of different chemical reactions in water. This review covers the research and application of cyclodextrins and their derivatives in asymmetric and stereospecific syntheses, with their division into three main groups: (1 cyclodextrins promoting asymmetric and stereospecific catalysis in water; (2 cyclodextrins’ complexes with transition metals as asymmetric and stereospecific catalysts; and (3 cyclodextrins’ non-metallic derivatives as asymmetric and stereospecific catalysts. The scope of this review is to systematize existing information on the contribution of cyclodextrins to asymmetric and stereospecific synthesis and, thus, to facilitate further development in this direction.

  10. Investigation on mass flux distribution and asymmetrical cooling in a plate-type fuel reactor

    International Nuclear Information System (INIS)

    A program was developed to calculate the mass flux distribution in the whole core and the asymmetrical cooling of fuel pins for a plate type fuel reactor by applying the proper physical model. Three iterative algorithms for mass flux distribution calculation and two iterative algorithms for temperature field calculation of plate fuel element under asymmetrical cooling condition were proposed and compared by applying in a subassembly. The results showed that the flow distribution is mainly determined by the core structure, although it is also impacted by the power distribution in the core. The asymmetrical cooling condition seriously impacts the temperature field and power distribution of the fuel pins. (authors)

  11. Pumping and mixing in a microchannel using AC asymmetric electrode arrays

    International Nuclear Information System (INIS)

    A numerical study of electroosmotic microchannel flow driven by arrays of AC (alternating current) asymmetric electrodes was carried out. By installing asymmetric electrode arrays on the top and bottom walls of the microchannel, pumping and mixing flow modes can be generated. The 'pumping mode' (P) is generated when the sequences of asymmetric electrode pairs (narrow to wide) on the top and bottom walls are in phase, whereas the 'mixing mode' (M) is generated by switching the sequence of electrode pairs of the top wall (e.g., wide to narrow). By combining mixing and pumping modes, enhanced mixing performance can be achieved without significantly reducing the flow rate. Among various combinations of P and M modes, the alternating PM mode showed the best mixing performance due to the iterative convergent and divergent flow motions. The effects of Peclet number and channel height on the mixing efficiency were analyzed in detail

  12. Stable walking with asymmetric legs

    International Nuclear Information System (INIS)

    Asymmetric leg function is often an undesired side-effect in artificial legged systems and may reflect functional deficits or variations in the mechanical construction. It can also be found in legged locomotion in humans and animals such as after an accident or in specific gait patterns. So far, it is not clear to what extent differences in the leg function of contralateral limbs can be tolerated during walking or running. Here, we address this issue using a bipedal spring-mass model for simulating walking with compliant legs. With the help of the model, we show that considerable differences between contralateral legs can be tolerated and may even provide advantages to the robustness of the system dynamics. A better understanding of the mechanisms and potential benefits of asymmetric leg operation may help to guide the development of artificial limbs or the design novel therapeutic concepts and rehabilitation strategies.

  13. Asymmetric Trade Estimator in Modified Gravity: Corporate Tax Rates and Trade in OECD Countries

    OpenAIRE

    Estelle P. Dauchy; Christopher Balding

    2013-01-01

    To study the potentially distortionary impact of differing corporate income tax rates on international trade flows, we use an augmented empirical specification of the gravity model. Incorporating an asymmetric trade barrier measure into a modified gravity model, we capture the impact of corporate income tax rates via the price mechanism impact on trade. Holding other factors constant in a gravity model, one should theoretically expect asymmetric corporate income tax rates to impact bilateral ...

  14. The design of an asymmetric bionic branching channel for electronic chips cooling

    Science.gov (United States)

    Xu, Shanglong; Qin, Jie; Guo, Wei; Fang, Kuang

    2013-06-01

    Inspired by the wing vein of Lepidoptera, a designment of asymmetric bionic branching channel for electronic chips cooling is developed. Lepidoptera vein D was chosen to measure the angle of first and second branch level. Based on these regular patterns, an asymmetric bionic branching channel is designed in a 35 mm × 35 mm chip. Comparing with fractal-like branching channel, it provides a stronger heat transfer capability, lower pressure drop and lower flow resistance in the experiment.

  15. Asymmetrically coupled directed percolation systems

    OpenAIRE

    Noh, Jae Dong; Park, Hyunggyu

    2005-01-01

    We introduce a dynamical model of coupled directed percolation systems with two particle species. The two species $A$ and $B$ are coupled asymmetrically in that $A$ particles branch $B$ particles whereas $B$ particles prey on $A$ particles. This model may describe epidemic spreading controlled by reactive immunization agents. We study nonequilibrium phase transitions with focused attention to the multicritical point where both species undergo the absorbing phase transition simultaneously. In ...

  16. Asymmetric information and macroeconomic dynamics

    Science.gov (United States)

    Hawkins, Raymond J.; Aoki, Masanao; Roy Frieden, B.

    2010-09-01

    We show how macroeconomic dynamics can be derived from asymmetric information. As an illustration of the utility of this approach we derive the equilibrium density, non-equilibrium densities and the equation of motion for the response to a demand shock for productivity in a simple economy. Novel consequences of this approach include a natural incorporation of time dependence into macroeconomics and a common information-theoretic basis for economics and other fields seeking to link micro-dynamics and macro-observables.

  17. Entrepreneurship, Asymmetric Information and Unemployment

    OpenAIRE

    Robin Boadway; Nicolas Marceau; Maurice Marchand; Marianne Vigneault

    1998-01-01

    We examine how three sources of asymmetric information affect the supply of entrepreneurs and unemployment. In the first case, banks cannot observe entrepreneurs' risk of failure so ration credit. This increases the number of entrepreneurs and the level of unemployment. In the second case, firms cannot observe workers' effort so offer a wage above the market clearing one. This results in unemployment and too few entrepreneurs. The final case arises when firms cannot observe workers' abilities...

  18. Asymmetric Microscopic Driving Behavior Theory

    OpenAIRE

    Yeo, Hwasoo

    2008-01-01

    Numerous theories on traffic have been developed as traffic congestion gains more and more interest in our daily life. To model traffic phenomena, many traffic theorists have adopted theories from other fields such as fluid mechanics and thermodynamics. However, their efforts to model the traffic at a microscopic level have not been successful yet. Therefore, to overcome the limitations of the existing theories we propose a microscopic asymmetric traffic theory based on analysis of individual...

  19. Effciency Concern under Asymmetric Information

    OpenAIRE

    Winschel, Evguenia; Zahn, Philipp

    2012-01-01

    Experimental evidence from simple distribution games supports the view that some individuals have a concern for the effciency of allocations. This motive could be important for the implementation of economic policy proposals. In a typical lab experiment, however, individuals have much more information available than outside the lab. We conduct a lab experiment to test whether asymmetric information influences prosocial behavior in a simple non-strategic interaction. In our setting, a dictator...

  20. Nonlinear vocal fold dynamics resulting from asymmetric fluid loading on a two-mass model of speech

    Science.gov (United States)

    Erath, Byron D.; Zañartu, Matías; Peterson, Sean D.; Plesniak, Michael W.

    2011-09-01

    Nonlinear vocal fold dynamics arising from asymmetric flow formations within the glottis are investigated using a two-mass model of speech with asymmetric vocal fold tensioning, representative of unilateral vocal fold paralysis. A refined theoretical boundary-layer flow solver is implemented to compute the intraglottal pressures, providing a more realistic description of the flow than the standard one-dimensional, inviscid Bernoulli flow solution. Vocal fold dynamics are investigated for subglottal pressures of 0.6 vocal fold dynamics at subglottal pressures that are associated with normal speech, behavior that is not captured with standard Bernoulli flow solvers. Regions of bifurcation, coexistence of solutions, and chaos are identified.

  1. Incompressibility of asymmetric nuclear matter

    International Nuclear Information System (INIS)

    Using an isospin- and momentum-dependent modified Gogny (MDI) interaction, the Skyrme-Hartree-Fock (SHF) approach, and a phenomenological modified Skyrme-like (MSL) model, we have studied the incompressibility Ksat(δ) of isospin asymmetric nuclear matter at its saturation density. Our results show that in the expansion of Ksat(δ) in powers of isospin asymmetry δ, i.e., Ksat(δ) = K0 + Ksat,2δ2 + Ksat,4δ4 + O(δ6), the magnitude of the 4th-order Ksat,4 parameter is generally small. The 2nd-order Ksat,2 parameter thus essentially characterizes the isospin dependence of the incompressibility of asymmetric nuclear matter at saturation density. Furthermore, the Ksat,2 can be expressed as Ksat,2 = Ksym – 6L – J0/K0 L in terms of the slope parameter L and the curvature parameter Ksym of the symmetry energy and the third-order derivative parameter J0 of the energy of symmetric nuclear matter at saturation density, and we find the higher order J0 contribution to Ksat,2 generally cannot be neglected. Also, we have found a linear correlation between Ksym and L as well as between J0/K0 and K0. Using these correlations together with the empirical constraints on K0 and L, the nuclear symmetry energy Esym(ρ0) at normal nuclear density, and the nucleon effective mass, we have obtained an estimated value of Ksat,2 = -370 ± 120 MeV for the 2nd-order parameter in the isospin asymmetry expansion of the incompressibility of asymmetric nuclear matter at its saturation density. (author)

  2. Asymmetric Information and Consumer Demand

    OpenAIRE

    Ismagilova G. N.; Danilina E. I.; Gafurov I. R.; Ismagilov R. I.; Safiullin L. N.

    2014-01-01

    In the paper study the peculiarities of the formation the consumer demand for durable goods, the so-called «experience goods» in markets with asymmetric information. In the known literature sources studying of the demand is based on the assumption that at the moment of the purchase of goods and services people know exactly what price they are willing to pay for them and what utility they are going to obtain using those goods and services. Consider the signal model in which the initial price a...

  3. Transient Stability During Asymmetrical Faults

    OpenAIRE

    Couturier, Nicolas

    2015-01-01

    This research project has been conducted at RTE in order to study the transient stability after asymmetrical faults. When three-phase short-circuits occur in a network, almost all the electrical power is lost on the relevant line(s). Among all short-circuit types, it is the most drastic event and the issue has to be solved very quickly. But oddly, it is also the easiest problem to solve mathematically speaking. This comes from the fact that the system stays balanced, and equations can be simp...

  4. Phase equilibria in asymmetric mixtures

    International Nuclear Information System (INIS)

    The simplified version of the Perturbed Hard-Chain Theory (SPHCT) is used to compute the phase equilibria and Henry's constants for mixtures in which the molecules are highly asymmetric both in shape and in the intermolecular potential. These mixtures include binary systems such as CO2/hydrocarbons and hydrocarbons/hydrocarbons, which are of particular interest for the oil industry. For this type of mixtures a single parameter (which is calculated from available experimental data of liquid-vapor equilibrium) is introduced. The approach yields results which compare well with the experimental behavior reported in the literature (Author)

  5. Physical mechanism of Eψ-driven current in asymmetric toroidal system

    International Nuclear Information System (INIS)

    Physical mechanism of the Eψ-driven neoclassical current which exists only in asymmetric toroidal systems is clarified. It found that symmetry-breaking, violating the total angular momentum conservation, changes the direction of flow and heat flux to be damped by the parallel viscosities. The change in the direction depends on the collisionality through the gemetric factor which reflects symmetry-breaking. As a result, in contrast to symmetric toroidal systems, the flow and heat flux due to the radial electric field Eψ can damped according to the collisionality in asymmetric toroidal systems. If dominant species such as electrons and primary ions have different collisionalities, there remains a difference between the flows due to Eψ, hence a parallel current proportional directly to the radial electric field, i,e., the Eψ-driven current, is generated in asymmetric toroidal systems in spit of the charge neutrality condition. (author)

  6. Physical mechanism of Eψ-driven current in asymmetric toroidal systems

    International Nuclear Information System (INIS)

    Physical mechanism of the Eψ-driven neoclassical current which exists only in asymmetric toroidal systems is clarified. It is found that symmetry-breaking, violating the total angular momentum conservation, changes the direction of flow and heat flux to be damped by the parallel viscosities. The change in the direction depends on the collisionality through the geometric factor which reflects symmetry-breaking. As a result, in contrast to symmetric toroidal systems, the flow and heat flux due to the radial electric field Eψ can be damped according to the collisionality in asymmetric toroidal systems. If dominant species such as electrons and primary ions have different collisionalities, there remains a difference between the flow due to Eψ, hence a parallel current proportional directly to the radial electric field, i.e., the Eψ-driven current, is generated in asymmetric toroidal systems in spite of the charge neutrality condition. (author)

  7. Tripartite fully asymmetric universal quantum cloning

    International Nuclear Information System (INIS)

    Full text: We investigate the universal asymmetric cloning of states in a Hilbert space of arbitrary dimension d. We derive the class of optimal and fully asymmetric universal 1 → 3 cloners, which produce three copies, each having a different fidelity. A simple parametric expression for the maximum achievable cloning fidelity triplets will be provided. As a side-product, we also prove the optimality of the 1 → 2 asymmetric cloning machines that have been proposed in the literature. (author)

  8. Enhanced Asymmetric Bilinear Model for Face Recognition

    OpenAIRE

    Wenjuan Gong; Weishan Zhang; Jordi Gonzàlez; Yan Ren; Zhen Li

    2015-01-01

    Bilinear models have been successfully applied to separate two factors, for example, pose variances and different identities in face recognition problems. Asymmetric model is a type of bilinear model which models a system in the most concise way. But seldom there are works exploring the applications of asymmetric bilinear model on face recognition problem with illumination changes. In this work, we propose enhanced asymmetric model for illumination-robust face recognition. Instead of initiali...

  9. Asymmetric Random Matrices: What do We Need them For?

    International Nuclear Information System (INIS)

    Complex systems are typically represented by large ensembles of observations. Correlation matrices provide an efficient formal framework to extract information from such multivariate ensembles and identify in a quantifiable way patterns of activity that are reproducible with statistically significant frequency compared to a reference chance probability, usually provided by random matrices as fundamental reference. The character of the problem and especially the symmetries involved must guide the choice of random matrices to be used for the definition of a baseline reference. For standard correlation matrices this is the Wishart ensemble of symmetric random matrices. The real world complexity however often shows asymmetric information flows and therefore more general correlation matrices are required to adequately capture the asymmetry. Here we first summarize the relevant theoretical concepts. We then present some examples of human brain activity where asymmetric time-lagged correlations are evident and hence highlight the need for further theoretical developments. (author)

  10. Asymmetric random matrices: What do we need them for?

    CERN Document Server

    Drozdz, Stanislaw; Ioannides, Andreas A; 10.5506/APhysPolB.42.987

    2011-01-01

    Complex systems are typically represented by large ensembles of observations. Correlation matrices provide an efficient formal framework to extract information from such multivariate ensembles and identify in a quantifiable way patterns of activity that are reproducible with statistically significant frequency compared to a reference chance probability, usually provided by random matrices as fundamental reference. The character of the problem and especially the symmetries involved must guide the choice of random matrices to be used for the definition of a baseline reference. For standard correlation matrices this is the Wishart ensemble of symmetric random matrices. The real world complexity however often shows asymmetric information flows and therefore more general correlation matrices are required to adequately capture the asymmetry. Here we first summarize the relevant theoretical concepts. We then present some examples of human brain activity where asymmetric time-lagged correlations are evident and hence...

  11. Aberrations in asymmetrical electron lenses

    International Nuclear Information System (INIS)

    Starting from well established knowledge in light-optics we explore the question if electron-optical aberration can be improved in asymmetrical electron lenses. We show that spherical as well as chromatic aberration coefficients are reduced in asymmetric electrostatic einzel lenses when the center electrode is moved away from the center position towards the entrance electrode. Relative improvements up to 40% for both the chromatic and the spherical aberration coefficients can be obtained. We use analytical and numerical calculations to confirm this result for exemplary cases of a lens with fixed length and working distance. The agreement of the two calculation methods is very good. We then derive an estimate for the electron-optical aberration coefficients from light-optics. The derived expressions for chromatic and spherical aberrations are somewhat simpler than the ones derived from electron-optics as they involve integrals only over the electrostatic potential, not over the electron paths. The estimated formulas still agree well with the electron optical calculations. Overall, we are tempted to suggest that the enormous knowledge base of light optics can provide considerable guidance for electron-optical applications. -- Highlights: ► Develops the analogy between light and electron optics in aberration calculations. ► Optimized spherical and chromatic aberrations for an electrostatic einzel lens. ► Comparison between analytic and numerical aberration calculations.

  12. Aberrations in asymmetrical electron lenses.

    Science.gov (United States)

    Fitzgerald, J P S; Word, R C; Könenkamp, R

    2012-08-01

    Starting from well established knowledge in light-optics we explore the question if electron-optical aberration can be improved in asymmetrical electron lenses. We show that spherical as well as chromatic aberration coefficients are reduced in asymmetric electrostatic einzel lenses when the center electrode is moved away from the center position towards the entrance electrode. Relative improvements up to 40% for both the chromatic and the spherical aberration coefficients can be obtained. We use analytical and numerical calculations to confirm this result for exemplary cases of a lens with fixed length and working distance. The agreement of the two calculation methods is very good. We then derive an estimate for the electron-optical aberration coefficients from light-optics. The derived expressions for chromatic and spherical aberrations are somewhat simpler than the ones derived from electron-optics as they involve integrals only over the electrostatic potential, not over the electron paths. The estimated formulas still agree well with the electron optical calculations. Overall, we are tempted to suggest that the enormous knowledge base of light optics can provide considerable guidance for electron-optical applications. PMID:22206603

  13. Excitons in asymmetric quantum wells

    Science.gov (United States)

    Grigoryev, P. S.; Kurdyubov, A. S.; Kuznetsova, M. S.; Ignatiev, I. V.; Efimov, Yu. P.; Eliseev, S. A.; Petrov, V. V.; Lovtcius, V. A.; Shapochkin, P. Yu.

    2016-09-01

    Resonance dielectric response of excitons is studied for the high-quality InGaAs/GaAs heterostructures with wide asymmetric quantum wells (QWs). To highlight effects of the QW asymmetry, we have grown and studied several heterostructures with nominally square QWs as well as with triangle-like QWs. Several quantum confined exciton states are experimentally observed as narrow exciton resonances. A standard approach for the phenomenological analysis of the profiles is generalized by introducing different phase shifts for the light waves reflected from the QWs at different exciton resonances. Good agreement of the phenomenological fit to the experimentally observed exciton spectra for high-quality structures allowed us to reliably obtain parameters of the exciton resonances: the exciton transition energies, the radiative broadenings, and the phase shifts. A direct numerical solution of the Schrödinger equation for the heavy-hole excitons in asymmetric QWs is used for microscopic modeling of the exciton resonances. Remarkable agreement with the experiment is achieved when the effect of indium segregation is taken into account. The segregation results in a modification of the potential profile, in particular, in an asymmetry of the nominally square QWs.

  14. ASYMMETRIC SOLAR POLAR FIELD REVERSALS

    International Nuclear Information System (INIS)

    The solar polar fields reverse because magnetic flux from decaying sunspots moves toward the poles, with a preponderance of flux from the trailing spots. If there is a strong asymmetry, in the sense that most activity is in the northern hemisphere, then that excess flux will move toward the north pole and reverse that pole first. If there is more activity in the south later on, then that flux will help to reverse the south pole. In this way, two humps in the solar activity and a corresponding difference in the time of reversals develop (in the ideal case). Such a difference was originally noted in the very first observation of polar field reversal just after the maximum of the strongly asymmetric solar cycle 19, when the southern hemisphere was most active before sunspot maximum and the south pole duly reversed first, followed by the northern hemisphere more than a year later, when that hemisphere became most active. Solar cycles since then have had the opposite asymmetry, with the northern hemisphere being most active before solar maximum. We show that polar field reversals for these cycles have all happened in the north first, as expected. This is especially noteworthy for the present solar cycle 24. We suggest that the association of two or more peaks of solar activity when separated by hemispheres with correspondingly different times of polar field reversals is a general feature of the cycle, and that asymmetric polar field reversals are simply a consequence of the asymmetry of solar activity.

  15. Asymmetric Laguerre-Gaussian beams

    Science.gov (United States)

    Kovalev, A. A.; Kotlyar, V. V.; Porfirev, A. P.

    2016-06-01

    We introduce a family of asymmetric Laguerre-Gaussian (aLG) laser beams. The beams have been derived via a complex-valued shift of conventional LG beams in the Cartesian plane. While propagating in a uniform medium, the first bright ring of the aLG beam becomes less asymmetric and the energy is redistributed toward peripheral diffraction rings. The projection of the orbital angular momentum (OAM) onto the optical axis is calculated. The OAM is shown to grow quadratically with increasing asymmetry parameter of the aLG beam, which equals the ratio of the shift to the waist radius. Conditions for the OAM becoming equal to the topological charge have been derived. For aLG beams with zero radial index, we have deduced an expression to define the intensity maximum coordinates and shown the crescent-shaped intensity pattern to rotate during propagation. Results of the experimental generation and rotation of aLG beams agree well with theoretical predictions.

  16. Active matter on asymmetric substrates

    Science.gov (United States)

    Olson Reichhardt, C. J.; Drocco, J.; Mai, T.; Wan, M. B.; Reichhardt, C.

    2011-10-01

    For collections of particles in a thermal bath interacting with an asymmetric substrate, it is possible for a ratchet effect to occur where the particles undergo a net dc motion in response to an ac forcing. Ratchet effects have been demonstrated in a variety of systems including colloids as well as magnetic vortices in type-II superconductors. Here we examine the case of active matter or self-driven particles interacting with asymmetric substrates. Active matter systems include self-motile colloidal particles undergoing catalysis, swimming bacteria, artificial swimmers, crawling cells, and motor proteins. We show that a ratchet effect can arise in this type of system even in the absence of ac forcing. The directed motion occurs for certain particle-substrate interaction rules and its magnitude depends on the amount of time the particles spend swimming in one direction before turning and swimming in a new direction. For strictly Brownian particles there is no ratchet effect. If the particles reflect off the barriers or scatter from the barriers according to Snell's law there is no ratchet effect; however, if the particles can align with the barriers or move along the barriers, directed motion arises. We also find that under certain motion rules, particles accumulate along the walls of the container in agreement with experiment. We also examine pattern formation for synchronized particle motion. We discuss possible applications of this system for self-assembly, extracting work, and sorting as well as future directions such as considering collective interactions and flocking models.

  17. Finite Element Modeling of Roll Wear during Cold Asymmetric Sheet Rolling of Aluminum Alloy 5083

    Directory of Open Access Journals (Sweden)

    Pesin A.

    2015-01-01

    Full Text Available Since the main purpose of asymmetrical rolling is to impose high shear strains on the sheet, in order to obtain ultrafine grain structure, the friction between the rolls and the sheet has to be kept relatively high. This means that asymmetric rolling is performed with dry rolls. The paper presents a numerical analysis of the roll wear during asymmetric cold rolling of 5083 aluminum alloy. The finite element simulation was used to calculate the amount of roll wear by Usui’s equation. FEM simulations were carried out with using software DEFORM 2D. The influence of the friction coefficient on the roll wear and the material flow was discussed. The sliding velocity, interface pressure and temperature were used to calculate the roll wear. The results of simulation can be used to optimize the asymmetric rolling process to improve surface quality of aluminum sheets.

  18. Some Remarks on Asymmetric Syntheses from Recent Studies

    OpenAIRE

    Baba, Naomichi

    1990-01-01

    Some asymmetric syntheses were presented here and discussed briefly including NADH model reactions, phase transfer-catalyzed asymmetric epoxidation, enantiotopic group-selective hydrolysis of a malonic anhydride with alkoxide anion, intramolecular acid-catalyzed lactonizations, catalytic asymmetric Diels-Alder synthesis, asymmetric aldol condensation, chiral homoallyl alcohol synthesis, asymmetric addition of diethylzinc to aldehyde, kinetic resolution of racemic hydroperoxides and binaphthol...

  19. Classification of flow patterns in rectangular shallow reservoirs

    OpenAIRE

    DUFRESNE, Matthieu; Dewals, Benjamin; Erpicum, Sébastien; Archambeau, Pierre; Pirotton, Michel

    2010-01-01

    This work focuses on the experimental classification of flow patterns in rectangular shallow reservoirs, including symmetric flows without any reattachment point to asymmetric flows with one reattachment point, two reattachment points, or two reattachment points and one detachment point. The median position and the natural variability of the reattachment lengths of asymmetric flows were measured for forty geometric and hydraulic conditions. The effects of dimensionless flow depth, Froude numb...

  20. Condensation on Slippery Asymmetric Bumps

    CERN Document Server

    Park, Kyoo-Chul; He, Neil; Aizenberg, Joanna

    2015-01-01

    Bumps are omnipresent from human skin to the geological structures on planets, which offer distinct advantages in numerous phenomena including structural color, drag reduction, and extreme wettability. Although the topographical parameters of bumps such as radius of curvature of convex regions significantly influence various phenomena including anti-reflective structures and contact time of impacting droplets, the effect of the detailed bump topography on growth and transport of condensates have not been clearly understood. Inspired by the millimetric bumps of the Namib Desert beetle, here we report the identified role of radius of curvature and width of bumps with homogeneous surface wettability in growth rate, coalescence and transport of water droplets. Further rational design of asymmetric convex topography and synergetic combination with slippery coating simultaneously enable self-transport, leading to unseen five-fold higher growth rate and an order of magnitude faster shedding time of droplets compared...

  1. Asymmetric diffusion of cosmic rays

    CERN Document Server

    Medvedev, Mikhail V

    2015-01-01

    Cosmic ray propagation is diffusive because of pitch angle scattering by waves. We demonstrate that if the high-amplitude magnetohydrodynamic turbulence with $\\tilde B/\\langle B\\rangle \\sim 1$ is present on top of the mean field gradient, the diffusion becomes asymmetric. As an example, we consider the vertical transport of cosmic rays in our Galaxy propagating away from a point-like source. We solve this diffusion problem analytically using a one-dimensional Markov chain analysis. We obtained that the cosmic ray density markedly differs from the standard diffusion prediction and has a sizable effect on their distribution throughout the galaxy. The equation for the continuous limit is also derived, which shows limitations of the convection-diffusion equation.

  2. New asymmetric quantum codes over Fq

    Science.gov (United States)

    Ma, Yuena; Feng, Xiaoyi; Xu, Gen

    2016-07-01

    Two families of new asymmetric quantum codes are constructed in this paper. The first family is the asymmetric quantum codes with length n=qm-1 over Fq, where qge 5 is a prime power. The second one is the asymmetric quantum codes with length n=3m-1. These asymmetric quantum codes are derived from the CSS construction and pairs of nested BCH codes. Moreover, let the defining set T1=T2^{-q}, then the real Z-distance of our asymmetric quantum codes are much larger than δ _max+1, where δ _max is the maximal designed distance of dual-containing narrow-sense BCH code, and the parameters presented here have better than the ones available in the literature.

  3. Asymmetric Information and the Role of Accounting in Emerging Markets Evidences from TSE

    Directory of Open Access Journals (Sweden)

    Aida Dowran

    2013-02-01

    Full Text Available This study examines the value relevance (information content of cash flow and accounting figures in situations where the information is asymmetrical and Compare the relative information content of them to clarify the role of accounting figures in investment decision making and mitigating the agency problems (specifically resulting from the existence of information asymmetry in the emerging markets. Based on testing a sample of 76 firms from Tehran Stock Exchange (TSE during 2005 to 2011, the results support the priority of accounting figures over cash flows in the market (TSE. On the other hand, when the information is asymmetrical, the accounting figures are still more relevant than the cash flows and have more relative information content. At the same time, in small firms, the value relevance of the accounting figures compared to cash flows is more; while in large firms, the relative content of accounting figures and cash flow figures aren't significantly different.

  4. A computational study of asymmetric glottal jet deflection during phonation

    OpenAIRE

    Zheng, X.; Mittal, R; Bielamowicz, S.

    2011-01-01

    Two-dimensional numerical simulations are used to explore the mechanism for asymmetric deflection of the glottal jet during phonation. The model employs the full Navier–Stokes equations for the flow but a simple laryngeal geometry and vocal-fold motion. The study focuses on the effect of Reynolds number and glottal opening angle with a particular emphasis on examining the importance of the so-called “Coanda effect” in jet deflection. The study indicates that the glottal opening angle has no s...

  5. How the IMF By induces a By component in the closed magnetosphere and how it leads to asymmetric currents and convection patterns in the two hemispheres

    Science.gov (United States)

    Tenfjord, P.; Østgaard, N.; Snekvik, K.; Laundal, K. M.; Reistad, J. P.; Haaland, S.; Milan, S. E.

    2015-11-01

    We used the Lyon-Fedder-Mobarry global magnetohydrodynamics model to study the effects of the interplanetary magnetic field (IMF) By component on the coupling between the solar wind and magnetosphere-ionosphere system. When the IMF reconnects with the terrestrial magnetic field with IMF By≠0, flux transport is asymmetrically distributed between the two hemispheres. We describe how By is induced in the closed magnetosphere on both the dayside and nightside and present the governing equations. The magnetosphere imposes asymmetric forces on the ionosphere, and the effects on the ionospheric flow are characterized by distorted convection cell patterns, often referred to as "banana" and "orange" cell patterns. The flux asymmetrically added to the lobes results in a nonuniform induced By in the closed magnetosphere. By including the dynamics of the system, we introduce a mechanism that predicts asymmetric Birkeland currents at conjugate foot points. Asymmetric Birkeland currents are created as a consequence of y directed tension contained in the return flow. Associated with these currents, we expect fast localized ionospheric azimuthal flows present in one hemisphere but not necessarily in the other. We also present current density measurements from Active Magnetosphere and Planetary Electrodynamics Response Experiment that are consistent with this picture. We argue that the induced By produces asymmetrical Birkeland currents as a consequence of asymmetric stress balance between the hemispheres. Such an asymmetry will also lead to asymmetrical foot points and asymmetries in the azimuthal flow in the ionosphere. These phenomena should therefore be treated in a unified way.

  6. Computational analysis of asymmetric water entry of wedge and ship section at constant velocity

    Science.gov (United States)

    Rahaman, Md. Mashiur; Ullah, Al Habib; Afroz, Laboni; Shabnam, Sharmin; Sarkar, M. A. Rashid

    2016-07-01

    Water impact problems receive much attention due to their short duration and large unsteady component of hydrodynamic loads. The effect of water entry has several important applications in various aspects of the naval field. Significant attention has been given to various water entry phenomena such as ship slamming, planning hulls, high-speed hydrodynamics of seaplanes, surface-piercing propellers and the interaction of high-speed liquid drops with structural elements. Asymmetric water entry may be caused by various natural phenomena such as weather conditions or strong winds. Since the determination of hydrodynamic impact load plays a vital role in designing safe and effcient vessels, an accurate and reliable prediction method is necessary to investigate asymmetric water entry problems. In this paper, water entry of a two-dimensional wedge and ship section at constant velocity in asymmetric condition will be analysed numerically and the effects of asymmetric impact on the velocity and pressure distribution will be discussed. The finite volume method is employed to solve the dynamic motion of the wedge in two-phase flow. During the water entry, the air and water interface is described implicitly by the volume of fluid (VOF) scheme. The numerical code and method was first validated for symmetric condition by one of the present author is applied for asymmetric wedge and ship section. The free surface, velocity and pressure distribution for asymmetric water entry are investigated and visualized with contour plots at different time steps.

  7. Regenerating a symmetry in asymmetric dark matter.

    Science.gov (United States)

    Buckley, Matthew R; Profumo, Stefano

    2012-01-01

    Asymmetric dark matter theories generically allow for mass terms that lead to particle-antiparticle mixing. Over the age of the Universe, dark matter can thus oscillate from a purely asymmetric configuration into a symmetric mix of particles and antiparticles, allowing for pair-annihilation processes. Additionally, requiring efficient depletion of the primordial thermal (symmetric) component generically entails large annihilation rates. We show that unless some symmetry completely forbids dark matter particle-antiparticle mixing, asymmetric dark matter is effectively ruled out for a large range of masses, for almost any oscillation time scale shorter than the age of the Universe. PMID:22304253

  8. Modelling asymmetric growth in crowded plant communities

    DEFF Research Database (Denmark)

    Damgaard, Christian

    2010-01-01

    A class of models that may be used to quantify the effect of size-asymmetric competition in crowded plant communities by estimating a community specific degree of size-asymmetric growth for each species in the community is suggested. The model consists of two parts: an individual size......-asymmetric growth part, where growth is assumed to be proportional to a power function of the size of the individual, and a term that reduces the relative growth rate as a decreasing function of the individual plant size and the competitive interactions from other plants in the neighbourhood....

  9. Asymmetric warfare and the will to win

    OpenAIRE

    Quinn, Matthew D.

    2001-01-01

    This thesis explores the will to win in asymmetric war. Asymmetric war, in which one side has an overwhelming advantage over its opponent, will likely be the war of the future for the United States in the post-Cold War uni-polar world. To win an asymmetric war, the individual and then the masses must be motivated to fight and, ultimately, the will to win must be cultivated and sustained for victory. Religion is a highly effective motivat or for both the individual and the masses. This motiva...

  10. Experimental adiabatic vortex ratchet effect in Nb films with asymmetric pinning trap

    Indian Academy of Sciences (India)

    J E Villegas; N O nunez; M P Gonzalez; E M Gonalez; J L Vicent

    2006-01-01

    Nb films grown on top of an array of asymmetric pinning centers show a vortex ratchet effect. A net flow of vortices is induced when the vortex lattice is driven by fluctuating forces on an array of pinning centers without reflection symmetry. This effect occurs in the adiabatic regime and it could be mimiced only by reversible DC driven forces.

  11. Slip and heat transfer effects on peristaltic motion of a Carreau fluid in an asymmetric channel

    Energy Technology Data Exchange (ETDEWEB)

    Hayat, Tasawar [Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Mathematics; King Saud Univ., Riyadh (Saudi Arabia). Dept. of Mathematics; Saleem, Najma [Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Mathematics; Hendi, Awatif A. [Dept. of Physics, Riyadh (Saudi Arabia). Faculty of Science

    2010-12-15

    An analysis has been carried out for peristaltic flow and heat transfer of a Carreau fluid in an asymmetric channel with slip effect. The governing problem is solved under long wavelength approximation. The variations of pertinent dimensionless parameters on temperature are discussed. Pumping and trapping phenomena are studied. (orig.)

  12. Asymmetric Information and Consumer Demand

    Directory of Open Access Journals (Sweden)

    Ismagilova G. N.

    2014-11-01

    Full Text Available In the paper study the peculiarities of the formation the consumer demand for durable goods, the so-called «experience goods» in markets with asymmetric information. In the known literature sources studying of the demand is based on the assumption that at the moment of the purchase of goods and services people know exactly what price they are willing to pay for them and what utility they are going to obtain using those goods and services. Consider the signal model in which the initial price and advertising expenditures are the signals of the quality influencing the formation of the demand for new goods offered by the company of unknown quality through consumer behavior. The basis of this model is the study of producers by consumers, acquisition of knowledge, information about price and quality, as well as their use in order to determine the market share of high-quality goods and low-quality goods in the asymmetry of information.

  13. Chaos suppression through asymmetric coupling

    Science.gov (United States)

    Bragard, J.; Vidal, G.; Mancini, H.; Mendoza, C.; Boccaletti, S.

    2007-12-01

    We study pairs of identical coupled chaotic oscillators. In particular, we have used Roessler (in the funnel and no funnel regimes), Lorenz, and four-dimensional chaotic Lotka-Volterra models. In all four of these cases, a pair of identical oscillators is asymmetrically coupled. The main result of the numerical simulations is that in all cases, specific values of coupling strength and asymmetry exist that render the two oscillators periodic and synchronized. The values of the coupling strength for which this phenomenon occurs is well below the previously known value for complete synchronization. We have found that this behavior exists for all the chaotic oscillators that we have used in the analysis. We postulate that this behavior is presumably generic to all chaotic oscillators. In order to complete the study, we have tested the robustness of this phenomenon of chaos suppression versus the addition of some Gaussian noise. We found that chaos suppression is robust for the addition of finite noise level. Finally, we propose some extension to this research.

  14. Why Do Nucleosomes Unwrap Asymmetrically?

    Science.gov (United States)

    de Bruin, Lennart; Tompitak, Marco; Eslami-Mossallam, Behrouz; Schiessel, Helmut

    2016-07-01

    Nucleosomes, DNA spools with a protein core, engage about three-quarters of eukaryotic DNA and play a critical role in chromosomal processes, ranging from gene regulation, recombination, and replication to chromosome condensation. For more than a decade, micromanipulation experiments where nucleosomes are put under tension, as well as the theoretical interpretations of these experiments, have deepened our understanding of the stability and dynamics of nucleosomes. Here we give a theoretical explanation for a surprising new experimental finding: nucleosomes wrapped onto the 601 positioning sequence (the sequence used in most laboratories) respond highly asymmetrically to external forces by always unwrapping from the same end. Using a computational nucleosome model, we show that this asymmetry can be explained by differences in the DNA mechanics of two very short stretches on the wrapped DNA portion. Our finding suggests that the physical properties of nucleosomes, here the response to forces, can be tuned locally by the choice of the underlying base-pair sequence. This leads to a new view of nucleosomes: a physically highly varied set of DNA-protein complexes whose properties can be tuned on evolutionary time scales to their specific function in the genomic context. PMID:26991771

  15. Twin Higgs Asymmetric Dark Matter.

    Science.gov (United States)

    García García, Isabel; Lasenby, Robert; March-Russell, John

    2015-09-18

    We study asymmetric dark matter (ADM) in the context of the minimal (fraternal) twin Higgs solution to the little hierarchy problem, with a twin sector with gauged SU(3)^{'}×SU(2)^{'}, a twin Higgs doublet, and only third-generation twin fermions. Naturalness requires the QCD^{'} scale Λ_{QCD}^{'}≃0.5-20  GeV, and that t^{'} is heavy. We focus on the light b^{'} quark regime, m_{b^{'}}≲Λ_{QCD}^{'}, where QCD^{'} is characterized by a single scale Λ_{QCD}^{'} with no light pions. A twin baryon number asymmetry leads to a successful dark matter (DM) candidate: the spin-3/2 twin baryon, Δ^{'}∼b^{'}b^{'}b^{'}, with a dynamically determined mass (∼5Λ_{QCD}^{'}) in the preferred range for the DM-to-baryon ratio Ω_{DM}/Ω_{baryon}≃5. Gauging the U(1)^{'} group leads to twin atoms (Δ^{'}-τ^{'}[over ¯] bound states) that are successful ADM candidates in significant regions of parameter space, sometimes with observable changes to DM halo properties. Direct detection signatures satisfy current bounds, at times modified by dark form factors. PMID:26430985

  16. Twin Higgs Asymmetric Dark Matter

    CERN Document Server

    García, Isabel García; March-Russell, John

    2015-01-01

    We study Asymmetric Dark Matter (ADM) in the context of the minimal (Fraternal) Twin Higgs solution to the little hierarchy problem, with a twin sector with gauged $SU(3)' \\times SU(2)'$, a twin Higgs, and only third generation twin fermions. Naturalness requires the QCD$^\\prime$ scale $\\Lambda'_{\\rm QCD} \\simeq 0.5 - 20 \\ {\\rm GeV}$, and $t'$ to be heavy. We focus on the light $b'$ quark regime, $m_{b'} \\lesssim \\Lambda'_{\\rm QCD}$, where QCD$^\\prime$ is characterised by a single scale $\\Lambda'_{\\rm QCD}$ with no light pions. A twin baryon number asymmetry leads to a successful DM candidate: the spin-3/2 twin baryon, $\\Delta' \\sim b'b'b'$, with a dynamically determined mass ($\\sim 5 \\Lambda'_{\\rm QCD}$) in the preferred range for the DM-to-baryon ratio $\\Omega_{\\rm DM}/\\Omega_{\\rm baryon} \\simeq 5$. Gauging the $U(1)'$ group leads to twin atoms ($\\Delta'$ - $\\bar {\\tau'}$ bound states) that are successful ADM candidates in significant regions of parameter space, sometimes with observable changes to DM halo ...

  17. Local heat transfer downstream of an asymmetric abrupt expansion and cavity in a circular tube

    International Nuclear Information System (INIS)

    This study is concerned with measuring local heat transfer downstream of an asymmetric abrupt expansion and an asymmetric abrupt expansion followed by an asymmetric abrupt contraction (called 'asymmetric cavity') in a circular tube at a uniform wall temperature. The effects of geometry and three- dimensionality of the flow caused by asymmetric expansion on heat transfer characteristics are also examined. The flow just upstream of the expansion is unheated and fully developed at the entrance to the heated asymmetric abrupt expansion region. Local heat transfer coefficients are measured using a specially designed isothermal heat flux sensor. Measurements for the asymmetric abrupt expansion are made at a small to large diameter ratio of d/D = 0.4 and 0.533 for Reynolds numbers of ReD = 17,300 and 21,900, respectively. The eccentricities of the tube axis (e/D) are 0.25 and 0.17 for d/D = 0.4, and 0.195 and 0.065 for d/D = 0.533. For the asymmetric cavity, all tests are made at d/D = 0.4 and ReD = 17,300 with various cavity lengths for e/D = 0 and 0.25, respectively. For both cases, the variations of local Nusselt number are observed along the wall of downstream circular tube at several angular positions around the tube circumference. In general, the local Nusselt numbers downstream of an asymmetric abrupt expansion are substantially higher than the fully developed values for the range of Reynolds numbers, diameter ratios and eccentricities investigated, due to high turbulence and mixing action in the recirculation region. And the maximum Nusselt numbers occur between 10 and 15 step heights from the expansion step. The Nusselt number distributions for the asymmetric cavity show a dramatic increase to the maximum values as the downstream region of the cavity is approached. This behavior is attributed to a periodic vortex shedding, subsequent impingement on the downstream corner region of the cavity and three-dimensionality effects which cause an increase in turbulence

  18. Asymmetric dense matter in holographic QCD

    Directory of Open Access Journals (Sweden)

    Shin Ik Jae

    2012-02-01

    Full Text Available We study asymmetric dense matter in holographic QCD.We construct asymmetric dense matter by considering two quark flavor branes with dierent quark masses in a D4/D6/D6 model. To calculate the symmetry energy in nuclear matter, we consider two quarks with equal masses and observe that the symmetry energy increases with the total charge showing the stiff dependence. This behavior is universal in the sense that the result is independent of parameters in the model. We also study strange (or hyperon matter with one light and one intermediate mass quarks. In addition to the vacuum properties of asymmetric matter, we calculate meson masses in asymmetric dense matter and discuss our results in the light of in-medium kaon masses.

  19. Massless sunset diagrams in finite asymmetric volumes

    CERN Document Server

    Niedermayer, Ferenc

    2016-01-01

    In this paper we present methods to compute massless sunset diagrams in finite asymmetric volumes in the framework of dimensional regularization and lattice regularization. We also consider 1-loop sums in both regularizations.

  20. Worst Asymmetrical Short-Circuit Current

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Holmstrøm, O; Grastrup, L;

    2010-01-01

    In a typical power plant, the production scenario and the short-circuit time were found for the worst asymmetrical short-circuit current. Then, a sensitivity analysis on the missing generator values was realized in order to minimize the uncertainty of the results. Afterward the worst asymmetrical...... short-circuit current was analyzed in order to compare the results with the allowable DC current component based in the IEC. Finally the normal operating condition for the power plant was modeled....

  1. Renewable resource management under asymmetric information

    DEFF Research Database (Denmark)

    Jensen, Frank; Andersen, Peder; Nielsen, Max

    Asymmetric information between fishermen and the regulator is important within fisheries. The regulator may have less information about stock sizes, prices, costs, effort, productivity and catches than fishermen. With asymmetric information, a strong analytical tool is principal-agent analysis. In......-productivity agents receive an information rent. The information rent is equivalent to the total incentive cost. The incentive costs arise as we want to reveal the agent's type....

  2. An asymmetric pericyclic cascade approach to oxindoles

    OpenAIRE

    Richmond, Edward

    2014-01-01

    The research in this thesis describes an asymmetric pericyclic cascade approach to the synthesis of a range of enantioenriched oxindoles using enantiopure oxazolidine derived nitrones and disubstituted ketenes. Chapter 1 aims to place this work in the context of the literature, describing other commonly employed or state-of-the-art asymmetric approaches to oxindoles and related compounds. Examples of where these approaches have been used successfully in the total synthesis of related indol...

  3. Asymmetric Federalism in Russia: Cure or Poison?

    OpenAIRE

    Jorge Martinez-Vazquez

    2003-01-01

    In the early years of its existence, the Russian Federation adopted a system of differential treatment of its regions in order to cope with the great degree of diversity present in them. This paper examines the Russian Federation’s asymmetric federalism by evaluating the system’s role, significance and effects on the Federation’s development. The study incorporates a detailed description of the asymmetric federalism over time along with the benefits and costs incurred by its implementation. I...

  4. Asymmetric Membrane Osmotic Capsules for Terbutaline Sulphate

    OpenAIRE

    Gobade, N. G.; Marina Koland; K H Harish

    2012-01-01

    The aim of the present study was to design an asymmetric membrane capsule, an osmotic pump-based drug delivery system of ethyl cellulose for controlled release of terbutaline sulphate. asymmetric membrane capsules contains pore-forming water soluble additive, sorbitol in different concentrations in the capsule shell membrane, which after coming in contact with water, dissolves, resulting in an in situ formation of a microporous structure. The terbutaline sulphate is a β-adrenoreceptor agonist...

  5. Asymmetric septal hypertrophy and hypothyroidism in children.

    OpenAIRE

    Altman, D I; Murray, J.; Milner, S.; Dansky, R; Levin, S. E.

    1985-01-01

    Any echocardiographic study of two children with hypothyroidism demonstrated the presence of asymmetric septal hypertrophy. One child died aged 11 months, and pronounced thickening of the interventricular septum was confirmed at necropsy. There was also hypertrophy of the left ventricular free wall. Histological examination showed only slight muscle fibre disarray, but there was striking vacuolation and hypertrophy of muscle fibres. In the second case, a child aged five years, the asymmetric ...

  6. 非对称弯曲微流道中粒子惯性聚焦动态过程及流速调控机理研究%Dynamic process and flow-rate regulation mechanism of particle inertial focusing in an asymmetric ally curved microchannel

    Institute of Scientific and Technical Information of China (English)

    唐文来; 项楠; 张鑫杰; 黄笛; 倪中华

    2015-01-01

    In this paper, an asymmetrically curved microchannel device is designed and fabricated to quantitatively characterize the dynamic inertial focusing process of polystyrene particles and blood cells flowing along the channel. The experimental investigations are systematically carried out to probe into the regulation mechanisms of flow rate and particle size. Specifically, based on the particle fluorescent streak images and the corresponding intensity profiles at specific downstream positions, the lateral migration behaviors of particles in the mirochannel can be divided into two stages: the formation of focused streak and the shift of focusing position. It is also found that the channel structures with small radii are dominant during the whole inertial focusing process. A three-stage model is then presented to elucidate the flow-rate regulation mechanism in terms of the competition between inertial lift force and Dean drag force, according to the evolution of particle focusing dynamics with increasing flow rates. By making comparisons of focusing position and focusing ratio between two different-sized particles under various experimental conditions, we find that the larger particles have better focusing performances and stabilities, and the relative focusing position of different-sized particles can be adjusted by changing the driving flow rate. Finally, the applicability of the explored inertial focusing mechanisms for manipulating biological particles with complex features is investigated by analyzing the lateral migration behaviors of blood cells in the asymmetrically curved microchannel. The obtained conclusions are very important for understanding the particle focusing dynamics in micro-scale flows and developing the point-of-care diagnostic instruments.%设计制作了一种具有非对称弯曲微流道结构的微流控芯片,搭建实验平台定量表征聚苯乙烯粒子和血细胞沿流道的动态惯性聚焦过程, 并系统研究了流体流速和粒

  7. Fatigue in asymmetric-field-driven ferroelectric thin films

    International Nuclear Information System (INIS)

    The polarization fatigue problems in asymmetric-field-driven ferroelectric thin films is investigated in present Letter. The refreshment of fatigue induced by the application of asymmetric voltage to the top and bottom electrodes is modeled by asymmetric Schottky voltage barrier of a quantum well structure. The fatigue behavior under various asymmetric driving voltages and asymmetric driving pulses have been studied. Theoretical calculations are shown to be in agreement with experimental results

  8. High-Flow Asymmetric Reverse-Osmosis Membranes

    Science.gov (United States)

    Katz, M. C.; Wydeven, T. J.

    1984-01-01

    Water-soluble polymer membrane insolubilized by transition-metal salt. Thin layer of lower permeability material joined with thicker layer of highpermeability material. Two layers chemically identical or chemically distinct. They differ in density, compactness or other respects. Used to purify or desalinate seawater, brackish water, or industrial or domestic wastewater.

  9. Asymmetric plasmonic induced ionic noise in metallic nanopores

    Science.gov (United States)

    Li, Yi; Chen, Chang; Willems, Kherim; Lagae, Liesbet; Groeseneken, Guido; Stakenborg, Tim; van Dorpe, Pol

    2016-06-01

    We present distinct asymmetric plasmon-induced noise properties of ionic transport observed through gold coated nanopores. We thoroughly investigated the effects of bias voltage and laser illumination. We show that the potential drop across top-coated silicon nanocavity pores can give rise to a large noise asymmetry (~2-3 orders of magnitude). Varying the bias voltage has an appreciable effect on the noise density spectra, typically in the Lorentzian components. The laser power is found to strongly affect the ionic noise level as well as the voltage threshold for light-induced noise generation. The asymmetric noise phenomenon is attributed to plasmon-induced interfacial reactions which promote light-induced charge fluctuation in the ion flow and allow voltage modulation of photo-induced carriers surmounting over such Schottky junctions. We further compare the ionic noise performances of gold nanocavities containing different material stacks, among which thermal oxide passivation of the silicon successfully mitigates the light-induced noise and is also fully CMOS-compatible. The understanding of the described noise characteristics will help to foster multiple applications using related structures including plasmonic-based sensing or plasmon-induced catalysis such as water splitting or solar energy conversion devices.We present distinct asymmetric plasmon-induced noise properties of ionic transport observed through gold coated nanopores. We thoroughly investigated the effects of bias voltage and laser illumination. We show that the potential drop across top-coated silicon nanocavity pores can give rise to a large noise asymmetry (~2-3 orders of magnitude). Varying the bias voltage has an appreciable effect on the noise density spectra, typically in the Lorentzian components. The laser power is found to strongly affect the ionic noise level as well as the voltage threshold for light-induced noise generation. The asymmetric noise phenomenon is attributed to plasmon

  10. Keep-Left Behavior Induced by Asymmetrically Profiled Walls

    Science.gov (United States)

    Oliveira, C. L. N.; Vieira, A. P.; Helbing, D.; Andrade, J. S.; Herrmann, H. J.

    2016-01-01

    We show, computationally and analytically, that asymmetrically shaped walls can organize the flow of pedestrians driven in opposite directions through a corridor. Precisely, a two-lane ordered state emerges in which people always walk on the left-hand side (or right-hand side), controlled by the system's parameters. This effect depends on features of the channel geometry, such as the asymmetry of the profile and the channel width, as well as on the density and the drift velocity of pedestrians, and the intensity of noise. We investigate in detail the influence of these parameters on the flow and discover a crossover between ordered and disordered states. Our results show that an ordered state only appears within a limited range of drift velocities. Moreover, increasing noise may suppress such flow organization, but the flow is always sustained. This is in contrast with the "freezing by heating" phenomenon according to which pedestrians tend to clog in smooth channels for strong noise [Phys. Rev. Lett. 84, 1240 (2000)]. Therefore, the ratchetlike effect proposed here acts on the system not only to induce a "keep-left" behavior but also to prevent the freezing by heating clogging phenomenon. Besides pedestrian flow, this new phenomenon has other potential applications in microfluidics systems.

  11. Irregular vocal fold dynamics incited by asymmetric fluid loading in a model of recurrent laryngeal nerve paralysis

    Science.gov (United States)

    Sommer, David; Erath, Byron D.; Zanartu, Matias; Peterson, Sean D.

    2011-11-01

    Voiced speech is produced by dynamic fluid-structure interactions in the larynx. Traditionally, reduced order models of speech have relied upon simplified inviscid flow solvers to prescribe the fluid loadings that drive vocal fold motion, neglecting viscous flow effects that occur naturally in voiced speech. Viscous phenomena, such as skewing of the intraglottal jet, have the most pronounced effect on voiced speech in cases of vocal fold paralysis where one vocal fold loses some, or all, muscular control. The impact of asymmetric intraglottal flow in pathological speech is captured in a reduced order two-mass model of speech by coupling a boundary-layer estimation of the asymmetric pressures with asymmetric tissue parameters that are representative of recurrent laryngeal nerve paralysis. Nonlinear analysis identifies the emergence of irregular and chaotic vocal fold dynamics at values representative of pathological speech conditions.

  12. Control of apoptosis by asymmetric cell division.

    Science.gov (United States)

    Hatzold, Julia; Conradt, Barbara

    2008-04-01

    Asymmetric cell division and apoptosis (programmed cell death) are two fundamental processes that are important for the development and function of multicellular organisms. We have found that the processes of asymmetric cell division and apoptosis can be functionally linked. Specifically, we show that asymmetric cell division in the nematode Caenorhabditis elegans is mediated by a pathway involving three genes, dnj-11 MIDA1, ces-2 HLF, and ces-1 Snail, that directly control the enzymatic machinery responsible for apoptosis. Interestingly, the MIDA1-like protein GlsA of the alga Volvox carteri, as well as the Snail-related proteins Snail, Escargot, and Worniu of Drosophila melanogaster, have previously been implicated in asymmetric cell division. Therefore, C. elegans dnj-11 MIDA1, ces-2 HLF, and ces-1 Snail may be components of a pathway involved in asymmetric cell division that is conserved throughout the plant and animal kingdoms. Furthermore, based on our results, we propose that this pathway directly controls the apoptotic fate in C. elegans, and possibly other animals as well. PMID:18399720

  13. Asymmetric Magnon Excitation by Spontaneous Toroidal Ordering

    Science.gov (United States)

    Hayami, Satoru; Kusunose, Hiroaki; Motome, Yukitoshi

    2016-05-01

    The effects of spontaneous toroidal ordering on magnetic excitation are theoretically investigated for a localized spin model that includes a staggered Dzyaloshinsky-Moriya interaction and anisotropic exchange interactions, which arise from the antisymmetric spin-orbit coupling and the multiorbital correlation effect. We show that the model exhibits a Néel-type antiferromagnetic order, which simultaneously accompanies a ferroic toroidal order. We find that the occurrence of toroidal order modulates the magnon dispersion in an asymmetric way with respect to the wave number: a toroidal dipole order on the zigzag chain leads to a band-bottom shift, while a toroidal octupole order on the honeycomb lattice gives rise to a valley splitting. These asymmetric magnon excitations could be a source of unusual magnetic responses, such as nonreciprocal magnon transport. A variety of modulations are discussed while changing the lattice and magnetic symmetries. The implications regarding candidate materials for asymmetric magnon excitations are presented.

  14. Dc SQUIDs with asymmetric shunt resistors

    International Nuclear Information System (INIS)

    We have investigated asymmetrically shunted Nb/Al-AlOx/Nb dc SQUIDs. Simulations based on the coupled Langevin equations predict that the optimum energy resolution ε, and thus also the noise performance of such an asymmetric SQUID, can be 3-4 times better than that of its symmetric counterpart. While keeping the total resistance R identical to a comparable symmetric SQUID with R-1 = R1-1 + R2-1, we shunted only one of the two Josephson junctions with R = R1,2/2. Both types of SQUIDs were characterized with respect to their transport and noise properties at temperature T = 4.2 K, and we compared the experimental results with numerical simulations. Experiments yielded ε ∼ 32 ℎ for an asymmetric SQUID with an inductance L = 22 pH, whereas a comparable symmetric device achieved ε = 110 ℎ.

  15. DNA SECURITY USING SYMMETRIC AND ASYMMETRIC CRYPTOGRAPHY

    Directory of Open Access Journals (Sweden)

    Radu Terec

    2011-01-01

    Full Text Available This paper presents alternative security methods based on DNA. From the available alternative security methods, symmetric DNA algorithms were developed and implemented. The first symmetric DNA algorithm was implemented in the Java language, while the second DNA algorithm was implemented in BioJava and MatLab. Comparisons have been made between the performances of different standard symmetrical algorithms and the DNA proposed algorithms. As a new step to enhance the security, an asymmetric key generation inside a DNA security algorithm is presented. The asymmetric key generation algorithm starts from a password phrase. The asymmetric DNA algorithm proposes a mechanism which makes use of more encryption technologies. Therefore, it is more reliable and more powerful than the OTP DNA symmetric algorithms.

  16. Asymmetric Composite Nanoparticles with Anisotropic Surface Functionalities

    Directory of Open Access Journals (Sweden)

    Donglu Shi

    2009-01-01

    Full Text Available Asymmetric inorganic/organic composite nanoparticles with anisotropic surface functionalities represent a new approach for creating smart materials, requiring the selective introduction of chemical groups to dual components of composite, respectively. Here, we report the synthesis of snowman-like asymmetric silica/polystyrene heterostructure with anisotropic functionalities via a chemical method, creating nanostructure possibly offering two-sided biologic accessibility through the chemical groups. Carboxyl group was introduced to polystyrene component of the snowman-like composites by miniemulsion polymerization of monomer on local surface of silica particles. Moreover, amino group was then grafted to remained silica surface through facile surface modification of the composite nanoparticles. The asymmetric shape of these composites was confirmed by TEM characterization. Moreover, characteristics of anisotropic surface functionalities were indicated by Zeta potential measurement and confocal laser microscopy after being labeled with fluorescent dyes. This structure could find potential use as carriers for biological applications.

  17. Asymmetric membrane osmotic capsules for terbutaline sulphate

    Directory of Open Access Journals (Sweden)

    N G Gobade

    2012-01-01

    Full Text Available The aim of the present study was to design an asymmetric membrane capsule, an osmotic pump-based drug delivery system of ethyl cellulose for controlled release of terbutaline sulphate. asymmetric membrane capsules contains pore-forming water soluble additive, sorbitol in different concentrations in the capsule shell membrane, which after coming in contact with water, dissolves, resulting in an in situ formation of a microporous structure. The terbutaline sulphate is a β-adrenoreceptor agonist widely used in the treatment of asthma. The oral dosage regimen of terbutaline sulphate is 5 mg twice or thrice daily, the plasma half-life is approximate 3-4 h and it produces GI irritation with extensive first pass metabolism. Hence, terbutaline sulphate was chosen as a model drug with an aim to develop controlled release system. Different formulations of ethyl cellulose were prepared by phase inversion technique using different concentrations of sorbitol as pore forming agent. It was found that the thickness of the prepared asymmetric membrane capsules was increased with increase in concentration of ethyl cellulose and pore forming agent, i.e. sorbitol. The dye release study in water and 10% sodium chloride solution indicates that, the asymmetric membrane capsules follow osmotic principle to release content. The pores formed due to sorbitol were confirmed by microscopic observation of transverse section of capsule membrane. Data of in vitro release study of terbutaline sulphate from asymmetric membrane capsules indicated that, the capsules prepared with 10% and 12.5% of ethyl cellulose and 25% of sorbitol released as much as 97.44% and 76.27% in 12 h, respectively with zero order release rate. Hence asymmetric membrane capsule of 10% ethyl cellulose and 25% of sorbitol is considered as optimum for controlled oral delivery of terbutaline sulphate.

  18. Asymmetric membrane osmotic capsules for terbutaline sulphate.

    Science.gov (United States)

    Gobade, N G; Koland, Marina; Harish, K H

    2012-01-01

    The aim of the present study was to design an asymmetric membrane capsule, an osmotic pump-based drug delivery system of ethyl cellulose for controlled release of terbutaline sulphate. asymmetric membrane capsules contains pore-forming water soluble additive, sorbitol in different concentrations in the capsule shell membrane, which after coming in contact with water, dissolves, resulting in an in situ formation of a microporous structure. The terbutaline sulphate is a β-adrenoreceptor agonist widely used in the treatment of asthma. The oral dosage regimen of terbutaline sulphate is 5 mg twice or thrice daily, the plasma half-life is approximate 3-4 h and it produces GI irritation with extensive first pass metabolism. Hence, terbutaline sulphate was chosen as a model drug with an aim to develop controlled release system. Different formulations of ethyl cellulose were prepared by phase inversion technique using different concentrations of sorbitol as pore forming agent. It was found that the thickness of the prepared asymmetric membrane capsules was increased with increase in concentration of ethyl cellulose and pore forming agent, i.e. sorbitol. The dye release study in water and 10% sodium chloride solution indicates that, the asymmetric membrane capsules follow osmotic principle to release content. The pores formed due to sorbitol were confirmed by microscopic observation of transverse section of capsule membrane. Data of in vitro release study of terbutaline sulphate from asymmetric membrane capsules indicated that, the capsules prepared with 10% and 12.5% of ethyl cellulose and 25% of sorbitol released as much as 97.44% and 76.27% in 12 h, respectively with zero order release rate. Hence asymmetric membrane capsule of 10% ethyl cellulose and 25% of sorbitol is considered as optimum for controlled oral delivery of terbutaline sulphate. PMID:23204625

  19. Experimental investigation of symmetric and asymmetric heating of pressure tube under accident conditions for Indian PHWR

    International Nuclear Information System (INIS)

    Highlights: ► Circumferential temperature gradient for asymmetric heat-up was 400 °C. ► At same pressure ballooning initiates at lower temperature in asymmetrical heat-up. ► At 1 MPa ballooning initiated at 408 °C and with expansion rate of 0.005 mm/s. ► At 2 MPa ballooning initiation at 330 °C and with expansion rate of 0.0056 mm/s. ► For symmetrical heat-up strain rate was 10 times faster than asymmetric heat-up. - Abstract: In pressurized heavy water reactor (PHWR), under postulated scenario of small break Loss of Coolant Accident (LOCA) coincident with the failure of Emergency Core Cooling System (ECCS), a situation may arise under which reduction in mass flow rate of coolant through individual reactor channel can lead to stratified flow. Such stratified flow condition creates partial uncover of fuel bundle, which creates a circumferential temperature gradient over PT. The present investigation has been carried out to study thermo-mechanical behaviour of PT under asymmetric heating conditions for a 220 MWe PHWR. A 19-pin fuel simulator has been developed in which preferential heating of elements could be done by supplying power to the selected pins. The asymmetric heating of PT has been carried out at pressure 2 MPa and 1 MPa, respectively, by supplying power to upper region heating elements thus creating an half filled stratified flow conditions. The temperature difference up to 425 °C has been observed along top to bottom periphery of PT. A comparison is made between thermo-mechanical behaviour of PT under asymmetrical and symmetrical heat-up, expected from a large break LOCA condition. The radial expansion rate during symmetrical heating is found to be much faster as compared to that for asymmetric ballooning of PT at the same internal pressure. Integrity of PT is found to be maintained under both loading conditions. Heat sink around of test section, simulating moderator is found to be helpful in arresting the rise in temperature for both fuel

  20. Experimental investigation of symmetric and asymmetric heating of pressure tube under accident conditions for Indian PHWR

    Energy Technology Data Exchange (ETDEWEB)

    Yadav, Ashwini K., E-mail: ashwinikumaryadav@gmail.com [Department of Mechanical and Industrial Engineering, Indian Institute of Technology, Roorkee-247667 (India); Majumdar, P., E-mail: pmajum@barc.gov.in [Reactor Safety Division, Bhabha Atomic Research Centre, Mumbai-400085 (India); Kumar, Ravi, E-mail: ravikfme@iitr.ernet.in [Department of Mechanical and Industrial Engineering, Indian Institute of Technology, Roorkee-247667 (India); Chatterjee, B., E-mail: barun@barc.gov.in [Reactor Safety Division, Bhabha Atomic Research Centre, Mumbai-400085 (India); Gupta, Akhilesh, E-mail: akhilfme@iitr.ernet.in [Department of Mechanical and Industrial Engineering, Indian Institute of Technology, Roorkee-247667 (India); Lele, H.G., E-mail: hglele@barc.gov.in [Reactor Safety Division, Bhabha Atomic Research Centre, Mumbai-400085 (India)

    2013-01-15

    Highlights: Black-Right-Pointing-Pointer Circumferential temperature gradient for asymmetric heat-up was 400 Degree-Sign C. Black-Right-Pointing-Pointer At same pressure ballooning initiates at lower temperature in asymmetrical heat-up. Black-Right-Pointing-Pointer At 1 MPa ballooning initiated at 408 Degree-Sign C and with expansion rate of 0.005 mm/s. Black-Right-Pointing-Pointer At 2 MPa ballooning initiation at 330 Degree-Sign C and with expansion rate of 0.0056 mm/s. Black-Right-Pointing-Pointer For symmetrical heat-up strain rate was 10 times faster than asymmetric heat-up. - Abstract: In pressurized heavy water reactor (PHWR), under postulated scenario of small break Loss of Coolant Accident (LOCA) coincident with the failure of Emergency Core Cooling System (ECCS), a situation may arise under which reduction in mass flow rate of coolant through individual reactor channel can lead to stratified flow. Such stratified flow condition creates partial uncover of fuel bundle, which creates a circumferential temperature gradient over PT. The present investigation has been carried out to study thermo-mechanical behaviour of PT under asymmetric heating conditions for a 220 MWe PHWR. A 19-pin fuel simulator has been developed in which preferential heating of elements could be done by supplying power to the selected pins. The asymmetric heating of PT has been carried out at pressure 2 MPa and 1 MPa, respectively, by supplying power to upper region heating elements thus creating an half filled stratified flow conditions. The temperature difference up to 425 Degree-Sign C has been observed along top to bottom periphery of PT. A comparison is made between thermo-mechanical behaviour of PT under asymmetrical and symmetrical heat-up, expected from a large break LOCA condition. The radial expansion rate during symmetrical heating is found to be much faster as compared to that for asymmetric ballooning of PT at the same internal pressure. Integrity of PT is found to be

  1. Algebraic Davis Decomposition and Asymmetric Doob Inequalities

    Science.gov (United States)

    Hong, Guixiang; Junge, Marius; Parcet, Javier

    2016-04-01

    In this paper we investigate asymmetric forms of Doob maximal inequality. The asymmetry is imposed by noncommutativity. Let {({M}, τ)} be a noncommutative probability space equipped with a filtration of von Neumann subalgebras {({M}_n)_{n ≥ 1}} , whose union {bigcup_{n≥1}{M}_n} is weak-* dense in {{M}} . Let {{E}_n} denote the corresponding family of conditional expectations. As an illustration for an asymmetric result, we prove that for {1 algebraic atomic description for the involved Hardy spaces. The latter results are new even for commutative von Neumann algebras.

  2. Improved DFIG Capability during Asymmetrical Grid Faults

    DEFF Research Database (Denmark)

    Zhou, Dao; Blaabjerg, Frede

    In the wind power application, different asymmetrical types of the grid fault can be categorized after the Y/d transformer, and the positive and negative components of a single-phase fault, phase-to-phase fault, and two-phase fault can be summarized. Due to the newly introduced negative and even......, the capability of a 2 MW DFIG to ride through asymmetrical grid faults can be estimated at the existing design of the power electronics converter. Finally, a control scheme aimed to improve the DFIG capability is proposed and the simulation results validate its feasibility....

  3. Asymmetric acoustic transmission in multiple frequency bands

    International Nuclear Information System (INIS)

    We report both experimentally and numerically that the multi-band device of the asymmetric acoustic transmission is realized by placing two periodic gratings with different periods on both sides of two brass plates immersed in water. The asymmetric acoustic transmission can exist in four frequency bands below 1500 kHz, which arises from the interaction between various diffractions from the two gratings and Lamb modes in the brass plates immersed in water. The results indicate that the device has the advantages of multiple band, broader bandwidth, and simpler structure. Our finding should have great potential applications in ultrasonic devices

  4. Asymmetric plasmonic induced ionic noise in metallic nanopores.

    Science.gov (United States)

    Li, Yi; Chen, Chang; Willems, Kherim; Lagae, Liesbet; Groeseneken, Guido; Stakenborg, Tim; Van Dorpe, Pol

    2016-06-16

    We present distinct asymmetric plasmon-induced noise properties of ionic transport observed through gold coated nanopores. We thoroughly investigated the effects of bias voltage and laser illumination. We show that the potential drop across top-coated silicon nanocavity pores can give rise to a large noise asymmetry (∼2-3 orders of magnitude). Varying the bias voltage has an appreciable effect on the noise density spectra, typically in the Lorentzian components. The laser power is found to strongly affect the ionic noise level as well as the voltage threshold for light-induced noise generation. The asymmetric noise phenomenon is attributed to plasmon-induced interfacial reactions which promote light-induced charge fluctuation in the ion flow and allow voltage modulation of photo-induced carriers surmounting over such Schottky junctions. We further compare the ionic noise performances of gold nanocavities containing different material stacks, among which thermal oxide passivation of the silicon successfully mitigates the light-induced noise and is also fully CMOS-compatible. The understanding of the described noise characteristics will help to foster multiple applications using related structures including plasmonic-based sensing or plasmon-induced catalysis such as water splitting or solar energy conversion devices. PMID:27273622

  5. Analysis of Capillary Rise in Asymmetric Branch-Like Capillary

    Science.gov (United States)

    Li, Caoxiong; Shen, Yinghao; Ge, Hongkui; Yang, Zhihui; Su, Shuai; Ren, Kai; Huang, Heyu

    2016-05-01

    Transport in porous media is common in nature, attracting many attentions for a long time. Tree-like network model is often used as a simplification for porous space, expressing the complexity of pore spaces instead of capillary bundle. To investigate spontaneous imbibition characteristics in this network, a dynamic asymmetric branch-like capillary model is used to represent basic network structure, using fractal method to represent tortuosity. This work investigates the influence of parameters on imbibition process in the branch-like capillary model. An analytical equation for the imbibition mass versus time is derived. Parameters from capillary structures to liquid properties are taken into account and analyzed based on the numerical solution of the equation. It is found that the imbibition process in asymmetric branch-like capillary model can be recognized by four sections and brunching tubes are positive for imbibition process. Concomitantly, meniscus arrest event is simulated and discussed. Moreover, the influence of parameters on imbibition process is discussed. These parameters can be classified as static and dynamic. Static parameters mainly change the capillary force, which are related to the ultimate imbibition mass or imbibition ability, while dynamic parameters mainly have influence on resistance of flowing fluid, which are related to the imbibition speed in the imbibition process.

  6. Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations

    Directory of Open Access Journals (Sweden)

    Kivelä Antti

    2012-10-01

    Full Text Available Abstract Background Neointimal formation in atherosclerosis has been subject for intense research. However, good animal models mimicking asymmetrical lesion formation in human subjects have been difficult to establish. The aim of this study was to develop a model which would lead to the formation of eccentric lesions under macroscopically intact non-denuded endothelium. Methods We have developed a new collar model where we placed two cushions or dots inside the collar. Arterial lesions were characterized using histology and ultrasound methods. Results When this dotted collar was placed around carotid and femoral arteries it produced asymmetrical pressure on adventitia and a mild flow disturbance, and hence a change in shear stress. Our hypothesis was that this simple procedure would reproducibly produce asymmetrical lesions without any intraluminal manipulations. Intima/media ratio increased towards the distal end of the collar with the direction of blood flow under macroscopically intact endothelium. Macrophages preferentially accumulated in areas of the thickest neointima thus resembling early steps in human atherosclerotic plaque formation. Proliferating cells in these lesions and underlying media were scarce at eight weeks time point. Conclusion The improved dotted collar model produces asymmetrical human-like atherosclerotic lesions in rabbits. This model should be useful in studies regarding the pathogenesis and formation of eccentric atherosclerotic lesions.

  7. Magnetic field and rotation effects on peristaltic transport of a Jeffrey fluid in an asymmetric channel

    International Nuclear Information System (INIS)

    In this paper, the peristaltic flow of a Jeffrey fluid in an asymmetric rotating channel is studied. Mathematical modeling is carried out by utilizing long wavelength and low Reynolds number assumptions. Closed form expressions for the pressure gradient, pressure rise, streamlines, axial velocity and shear stress on the channel walls have been computed numerically. Effects of Hartmann number, the ratio of relaxation to retardation times, time-mean flow, rotation and the phase angle on the pressure gradient, pressure rise, streamline, axial velocity and shear stress are discussed in detail and shown graphically. The results indicate that the effect of the Hartmann number, the ratio of relaxation to retardation times, time-mean flow, rotation and the phase angle are very pronounced in the phenomena. Comparison was made with the results obtained in the asymmetric channel and symmetric channel. - Highlights: • The peristaltic flow of a Jeffrey fluid in an asymmetric rotating channel with magnetic field. • Mathematical modeling for long wavelength and low Reynolds number assumptions. • Closed form expressions for the pressure gradient, pressure rise, stream function, axial velocity and shear stress

  8. Asymmetric cell division: a persistent issue?

    OpenAIRE

    Aakre, Christopher D.; Laub, Michael T.

    2012-01-01

    Heterogeneity within a clonal population of cells can increase survival in the face of environmental stress. In a recent issue of Science, Aldridge et al. (2012) demonstrate that cell division in mycobacteria is asymmetric, producing daughter cells that differ in size, growth rate, and susceptibility to antibiotics.

  9. Asymmetric demand for energy: A cointegration approach

    Science.gov (United States)

    Maclean, Thomas Frank

    1997-12-01

    This paper uses time series data in a study of the demand for energy. One goal is to compare the results from the traditional autoregressive distributed lag (ADL) model to the error correction model (ECM) using cointegration. The second goal is to determine if the demand elasticity is asymmetric with respect to increasing and decreasing prices. This paper discusses three topics that are important to the use of time series data. The first topic is the presence and consequences unit roots which are common in time series data. The second topic is the identification of cointegrated variables and the third topic is a development of the ECM. This results in a model that can be used in either a single equation or multivariate system context and it will estimate both long run and short run elasticities. Asymmetry theory and its implications are studied along with an investigation into competing methods of creating the asymmetric variables. Simulations provided evidence that the use of dummy variables results in biased estimates and that the cumulative difference method of Wolffram/Houck gives valid estimates. The results of the empirical part of the paper show that the short run estimates of the ADL model are like those of the error correction model, but the cointegration method's long run estimates are better since they are known to be consistent and asymptotically unbiased. Tests for asymmetry do not support the theory of asymmetric long run price elasticities; however there is evidence to support the presence of asymmetric demand in the short run.

  10. Leverage bounds with default and asymmetric information

    Czech Academy of Sciences Publication Activity Database

    Boháček, Radim

    2014. [2014 North American Summer Meeting of the Econometric Society. Minneapolis (US), 19.06.2014-22.06.2014] R&D Projects: GA ČR GA402/09/1340 Institutional support: RVO:67985998 Keywords : financial markets and the macroeconomy * asymmetric and private information * occupational choice Subject RIV: AH - Economics http://editorialexpress.com/conference/NASM2014/program/NASM2014.html

  11. Asymmetric Taxation under Incremental and Sequential Investment

    OpenAIRE

    Panteghini, Paolo

    2002-01-01

    This article discusses the effects of an asymmetric tax scheme on incremental and sequential investment strategies. The tax base is equal to the firm’s return, net of an imputation rate. When the firm’s return is less than this rate, however, no tax refunds are allowed. This scheme is neutral under both income and capital uncertainty.

  12. Beam-beam issues in asymmetric colliders

    Energy Technology Data Exchange (ETDEWEB)

    Furman, M.A.

    1992-07-01

    We discuss generic beam-beam issues for proposed asymmetric e{sup +}- e{sup -} colliders. We illustrate the issues by choosing, as examples, the proposals by Cornell University (CESR-B), KEK, and SLAC/LBL/LLNL (PEP-II).

  13. Catalytic asymmetric synthesis of mycocerosic acid

    NARCIS (Netherlands)

    ter Horst, B.; Feringa, B.L.; J. Minnaard, A.

    2007-01-01

    The first catalytic asymmetric total synthesis of mycocerosic acid was achieved via the application of iterative enantioselective 1,4-addition reactions and allows for the efficient construction of 1,3-polymethyl arrays with full stereocontrol; further exemplified by the synthesis of tetramethyl-dec

  14. Evidence of asymmetric top in 130Ba

    International Nuclear Information System (INIS)

    Introduced is a new relation connecting moment of inertia, Lipas parameter and asymmetric rotor model energies and put forward much closer trend in odd even staggering of quasi γ-band. A different view point regarding generation of quasi γ-band in 130Ba have been presented

  15. Asymmetric conditional volatility in international stock markets

    Science.gov (United States)

    Ferreira, Nuno B.; Menezes, Rui; Mendes, Diana A.

    2007-08-01

    Recent studies show that a negative shock in stock prices will generate more volatility than a positive shock of similar magnitude. The aim of this paper is to appraise the hypothesis under which the conditional mean and the conditional variance of stock returns are asymmetric functions of past information. We compare the results for the Portuguese Stock Market Index PSI 20 with six other Stock Market Indices, namely the SP 500, FTSE 100, DAX 30, CAC 40, ASE 20, and IBEX 35. In order to assess asymmetric volatility we use autoregressive conditional heteroskedasticity specifications known as TARCH and EGARCH. We also test for asymmetry after controlling for the effect of macroeconomic factors on stock market returns using TAR and M-TAR specifications within a VAR framework. Our results show that the conditional variance is an asymmetric function of past innovations raising proportionately more during market declines, a phenomenon known as the leverage effect. However, when we control for the effect of changes in macroeconomic variables, we find no significant evidence of asymmetric behaviour of the stock market returns. There are some signs that the Portuguese Stock Market tends to show somewhat less market efficiency than other markets since the effect of the shocks appear to take a longer time to dissipate.

  16. Detection loophole in asymmetric Bell experiments

    OpenAIRE

    Brunner, Nicolas; Gisin, Nicolas; Scarani, Valerio; Simon, Christoph

    2007-01-01

    The problem of closing the detection loophole with asymmetric systems, such as entangled atom-photon pairs, is addressed. We show that, for the Bell inequality I_3322, a minimal detection efficiency of 43% can be tolerated for one of the particles, if the other one is always detected. We also study the influence of noise and discuss the prospects of experimental implementation.

  17. Asymmetric coherent transmission for single particle diode and gyroscope

    CERN Document Server

    Yang, S; Sun, C P

    2009-01-01

    We study the single particle scattering process in a coherent multi-site system consisting of a tight-binding ring threaded by an Aharonov-Bohm flux and several attaching leads. The asymmetric behavior of scattering matrix is discovered analytically in the framework of both Bethe Ansatz and Green's function formalism. It is found that, under certain conditions, a three-site electronic system can behave analogous to a perfect semiconductor diode where current flows only in one direction. The general result is also valid for a neutral particle system since the effective magnetic flux may be implemented by a globe rotation. This observation means that the three-site system can serve as an orientation measuring gyroscope due to the approximate linear dependence of the current difference of two output leads on the rotational angular velocity.

  18. Asymmetric pedestrian dynamics on a staircase landing from continuous measurements

    CERN Document Server

    Corbetta, Alessandro; Muntean, Adrian; Toschi, Federico

    2015-01-01

    We investigate via extensive experimental data the dynamics of pedestrians walking in a corridor-shaped landing in a building at Eindhoven University of Technology. With year-long automatic measurements employing a Microsoft KinectTM 3D-range sensor and ad hoc tracking techniques, we acquired few hundreds of thousands pedestrian trajectories in real-life conditions. Here we discuss the asymmetric features of the dynamics in the two walking directions with respect to the flights of stairs (i.e. ascending or descending). We provide a detailed analysis of position and speed fields for the cases of pedestrians walking alone undisturbed and for couple of pedestrians in counter-flow. Then, we show average walking velocities exploring all the observed combinations in terms of numbers of pedestrians and walking directions.

  19. Pentamode metamaterials with asymmetric double-cone elements

    International Nuclear Information System (INIS)

    Pentamode metamaterials are a very interesting set of artificial solids. They are difficult to compress but flow easily, hence imitating somehow the behaviours of liquids. In this paper, three-dimensional (3D) pentamode metamaterials based on the asymmetric double-cone element (ADCE) are proposed. The ADCE is composed by two connected truncated cones with different thin diameters. The phonon band structures of the ADCEs pentamode metamaterials are numerically analysed by using the finite element method (FEM). Besides the single phonon mode, the complete 3D band gaps are also found in the phonon band structures. Here, the influence of the degree of asymmetry of ADCE to the figure of merit (FOM), which is the ratio of bulk modulus and shear modulus, is discussed. The FOM can be increased by 21–30% (at FOM ≥ 103) when the degree of asymmetry m ranges from 0.4 to 0.6. (paper)

  20. Standards vs. labels with imperfect competition and asymmetric information

    DEFF Research Database (Denmark)

    Baltzer, Kenneth Thomas

    2012-01-01

    I demonstrate that providing information about product quality is not necessarily the best way to address asymmetric information problems when markets are imperfectly competitive. In a vertical differentiation model I show that a Minimum Quality Standard, which retains asymmetric information...

  1. Standards vs. labels with imperfect competition and asymmetric information

    DEFF Research Database (Denmark)

    Baltzer, Kenneth Thomas

    I demonstrate that providing information about product quality is not necessarily the best way to address asymmetric information problems when markets are imperfectly competitive. In a vertical dierentiation model I show that a Minimum Quality Standard, which retains asymmetric information...

  2. Asymmetric Bulkheads for Cylindrical Pressure Vessels

    Science.gov (United States)

    Ford, Donald B.

    2007-01-01

    Asymmetric bulkheads are proposed for the ends of vertically oriented cylindrical pressure vessels. These bulkheads, which would feature both convex and concave contours, would offer advantages over purely convex, purely concave, and flat bulkheads (see figure). Intended originally to be applied to large tanks that hold propellant liquids for launching spacecraft, the asymmetric-bulkhead concept may also be attractive for terrestrial pressure vessels for which there are requirements to maximize volumetric and mass efficiencies. A description of the relative advantages and disadvantages of prior symmetric bulkhead configurations is prerequisite to understanding the advantages of the proposed asymmetric configuration: In order to obtain adequate strength, flat bulkheads must be made thicker, relative to concave and convex bulkheads; the difference in thickness is such that, other things being equal, pressure vessels with flat bulkheads must be made heavier than ones with concave or convex bulkheads. Convex bulkhead designs increase overall tank lengths, thereby necessitating additional supporting structure for keeping tanks vertical. Concave bulkhead configurations increase tank lengths and detract from volumetric efficiency, even though they do not necessitate additional supporting structure. The shape of a bulkhead affects the proportion of residual fluid in a tank that is, the portion of fluid that unavoidably remains in the tank during outflow and hence cannot be used. In this regard, a flat bulkhead is disadvantageous in two respects: (1) It lacks a single low point for optimum placement of an outlet and (2) a vortex that forms at the outlet during outflow prevents a relatively large amount of fluid from leaving the tank. A concave bulkhead also lacks a single low point for optimum placement of an outlet. Like purely concave and purely convex bulkhead configurations, the proposed asymmetric bulkhead configurations would be more mass-efficient than is the flat

  3. A uniform measurement expression for cross method comparison of nanoparticle aggregate size distributions

    DEFF Research Database (Denmark)

    Dudkiewicz, Agnieszka; Wagner, Stephan; Lehner, Angela;

    2015-01-01

    techniques: scanning electron microscopy in both high vacuum (SEM) and liquid cell setup (Wet-SEM); gasphase electrophoretic mobility molecular analyzer (GEMMA); centrifugal liquid sedimentation (CLS); nanoparticle tracking analysis (NTA); and asymmetric flow field flow fractionation with inductively coupled...

  4. Asymmetric three-dimensional topography over mantle plumes.

    Science.gov (United States)

    Burov, Evgueni; Gerya, Taras

    2014-09-01

    The role of mantle-lithosphere interactions in shaping surface topography has long been debated. In general, it is supposed that mantle plumes and vertical mantle flows result in axisymmetric, long-wavelength topography, which strongly differs from the generally asymmetric short-wavelength topography created by intraplate tectonic forces. However, identification of mantle-induced topography is difficult, especially in the continents. It can be argued therefore that complex brittle-ductile rheology and stratification of the continental lithosphere result in short-wavelength modulation and localization of deformation induced by mantle flow. This deformation should also be affected by far-field stresses and, hence, interplay with the 'tectonic' topography (for example, in the 'active/passive' rifting scenario). Testing these ideas requires fully coupled three-dimensional numerical modelling of mantle-lithosphere interactions, which so far has not been possible owing to the conceptual and technical limitations of earlier approaches. Here we present new, ultra-high-resolution, three-dimensional numerical experiments on topography over mantle plumes, incorporating a weakly pre-stressed (ultra-slow spreading), rheologically realistic lithosphere. The results show complex surface evolution, which is very different from the smooth, radially symmetric patterns usually assumed as the canonical surface signature of mantle upwellings. In particular, the topography exhibits strongly asymmetric, small-scale, three-dimensional features, which include narrow and wide rifts, flexural flank uplifts and fault structures. This suggests a dominant role for continental rheological structure and intra-plate stresses in controlling dynamic topography, mantle-lithosphere interactions, and continental break-up processes above mantle plumes. PMID:25186903

  5. New Evidence about the Spontaneous Symmetry Breaking: Action of an Asymmetric Weak Heat Source.

    Science.gov (United States)

    Mineo, Placido; Villari, Valentina; Scamporrino, Emilio; Micali, Norberto

    2015-09-17

    In the present study, we show how, in a stagnant water solution of uncharged aggregated achiral porphyrin-based molecules, a mirror-symmetry breaking (SB) can be induced and controlled by means of a weak asymmetric thermal gradient. In particular, it is shown that the optical activity of the aggregate porphyrin solution can be generated and reversed, in sign, only acting on the thermal ramp direction (heating or cooling). In order to avoid data misinterpretation, the aggregate structure modifications with the temperature change and the linear dichroism contribution to circular dichroism spectra were evaluated. A model simulation, using a finite element analysis approach describing the thermal flows, shows that small thermal gradients are able to give rise to asymmetric heat flow. The results reported here can be considered new evidence about the spontaneous symmetry breaking phenomenon induced by very weak forces having an important role in the natural chiral selective processes. PMID:26315854

  6. Process Design for Hot Forging of Asymmetric to Symmetric Rib-web Shaped Steel

    Directory of Open Access Journals (Sweden)

    H. Cho

    2003-01-01

    Full Text Available The process design of hot forging, asymmetric to symmetric rib-web shaped steel, which is used for the turnout of express rails has been studied. Owing to the great difference in shape between the initial billet and the final forged product, it is impossible to hot forge the rail in a single stage operation. Therefore, multi stage forging and also die design for each stage are necessary for the production process. The numerical simulation for hot forging of asymmetric shape to symmetric shape was carried out using commercial FEM code, DEFORMTM-2D. Modification of the design and repeated simulation was carried out on the basis of the simulation results. For comparison with the simulation results, a flow analysis experiment using plasticine was also carried out. The results of the flow analysis experiment showed good agreement with those of the simulation.

  7. Natural convection in asymmetric triangular enclosures heated from below

    International Nuclear Information System (INIS)

    Triangular enclosures are typical configurations of attic spaces found in residential as well as industrial pitched-roof buildings. Natural convection in triangular rooftops has received considerable attention over the years, mainly on right-angled and isosceles enclosures. In this paper, a finite volume CFD package is employed to study the laminar air flow and temperature distribution in asymmetric rooftop-shaped triangular enclosures when heated isothermally from the base wall, for aspect ratios (AR) 0.2 ≤ AR ≤ 1.0, and Rayleigh number (Ra) values 8 × 105 ≤ Ra ≤ 5 × 107. The effects of Rayleigh number and pitch angle on the flow structure and temperature distributions within the enclosure are analysed. Results indicate that, at low pitch angle, the heat transfer between the cold inclined and the hot base walls is very high, resulting in a multi-cellular flow structure. As the pitch angle increases, however, the number of cells reduces, and the total heat transfer rate progressively reduces, even if the Rayleigh number, being based on the enclosure height, rapidly increases. Physical reasons for the above effect are inspected

  8. On the retention mechanism of nanometer and micrometer size particles studied by micro-thermal field-flow fractionation: thermal diffusion and secondary effects

    Czech Academy of Sciences Publication Activity Database

    Janča, J.; Stejskal, Jaroslav; Ananieva, I. A.; Berneron, J.-F.; Gearing, J.; Minárik, M.

    Mondragon: Mondragon University Press, 2006 - (Bou-Ali, M.; Platten, J.), s. 337-345 ISBN 84-689-8814-6. [International Meeting on Thermodiffusion /7./. Donostia-San Sebastian (ES), 29.05.2006-02.06.2006] Institutional research plan: CEZ:AV0Z40500505 Keywords : colloidal particles * electrostatic interactions * lift -forces Subject RIV: CD - Macromolecular Chemistry

  9. Symmetry properties of the heat current in non-ballistic asymmetric junctions: A case study

    International Nuclear Information System (INIS)

    We consider quantum heat flow in two-terminal junctions and inquire on the connection between the transport mechanism and the junction functionality. Using simple models, we demonstrate that the violation of the Landauer behavior in asymmetric junctions does not necessarily imply the onset of thermal rectification. We also demonstrate through a simple example that a spatial inhomogeneity of the energy spectra is not a necessary condition for thermal rectification.

  10. Channelling Domestic Savings into Productive Investment Under Asymmetric Information: The Essential Role of Foreign Direct Investment

    OpenAIRE

    Razin, Assaf; Sadka, Efraim; Yuen, chi-wa

    1998-01-01

    Foreign direct investment (FDI) is observed to be a predominant form of capital flows to low and middle income countries with insufficiently developed capital markets. This paper analyzes the problem of channeling domestic savings into productive investment in the presence of asymmetric information between the managing owners of firms and other portfolio stakeholders. We emphasize the crucial role played by FDI in sustaining equity-financed capital investment for economies plagued by such inf...

  11. Asymmetric Information and the Role of Accounting in Emerging Markets Evidences from TSE

    OpenAIRE

    Aida Dowran; Hashem Valipour; Javad Moradi

    2013-01-01

    This study examines the value relevance (information content) of cash flow and accounting figures in situations where the information is asymmetrical and Compare the relative information content of them to clarify the role of accounting figures in investment decision making and mitigating the agency problems (specifically resulting from the existence of information asymmetry in the emerging markets). Based on testing a sample of 76 firms from Tehran Stock Exchange (TSE) during 2005 to 2011, t...

  12. A Default Model of The Non-listed Companies Under Asymmetric Information

    Institute of Scientific and Technical Information of China (English)

    Wang Fake

    2013-01-01

    For the financing difficulties of the non-listed companies, A continuous credit risk model is created which is based on the asymmetric information theory.In the model,the value of the non-listed companies is estimated by the free cash flow,and the loan discussed contains the collateral asset.Based on the model,The default probability,the LGD and the largest company debts are discussed.

  13. Collective flow in small systems

    International Nuclear Information System (INIS)

    The large density of matter in the interaction region of the proton–nucleus or deuteron–nucleus collisions enables the collective expansion of the fireball. Predictions of a hydrodynamic model for the asymmetric transverse flow are presented and compared to experimental data

  14. HEMODYNAMICS FOR ASYMMETRIC INLET AXIAL VELOCITY PROFILE IN CAROTID BIFURCATION MODEL

    Institute of Scientific and Technical Information of China (English)

    DING Zu-rong; LIU Bin; YANG Shuo; XIA Yan

    2008-01-01

    The asymmetric inlet velocity profile has been observed in phantom model using LDA and in health subjects using Magnet Resonance (MR). The effects of asymmetric inlet axial velocity profile on the flow field and the Wall Shear Stress (WSS) ofcarotid bifurcation were numerically studied herein with the TF-AHCB model. The results show that the Wall Shear Stress Gradient (WSSG) in the front part of the sinus for inward-tilting inlet axial velocity profile is nearly 2 times of that for the symmetric one in the beginning of systole, the end of systole, and diastole, respectively. The area of WSS below 5x 10.3 Pa at the outer wall of the sinus for outward-tilting inlet axial velocity profile is 1.5 times of that for the inward-tilting one during diastole of the cardiac cycle. The asymmetric inlet velocity profiles can reduce the flow velocity near the inner wall of the sinus, which has been normally considered a high velocity region. It is concluded that besides bifurcation geometry and flow waveform, the asymmetry of inlet velocity profile is probably a factor influencing atherosclerosis.

  15. ON ASYMMETRIC DISTRIBUTIONS OF SATELLITE GALAXIES

    International Nuclear Information System (INIS)

    We demonstrate that the asymmetric distribution of M31 satellites cannot be produced by tides from the Milky Way as such effects are too weak. However, loosely bound associations and groups of satellites can fall into larger halos and give rise to asymmetries. We compute the survival times for such associations. We prove that the survival time is always shortest in Keplerian potentials, and can be ∼3 times longer in logarithmic potentials. We provide an analytical formula for the dispersal time in terms of the size and velocity dispersion of the infalling structure. We show that, if an association of ∼10 dwarfs fell into the M31 halo, its present aspect would be that of an asymmetric disk of satellites. We also discuss the case of cold substructure in the Andromeda II and Ursa Minor dwarfs

  16. Cosmological signatures of time-asymmetric gravity

    CERN Document Server

    Cortês, Marina; Smolin, Lee

    2016-01-01

    We develop the model proposed by Cort\\^es, Gomes & Smolin, to predict cosmological signatures of time-asymmetric extensions of general relativity they proposed recently. Within this class of models the equation of motion of chiral fermions is modified by a torsion term. This term leads to a dispersion law for neutrinos that associates a new time-varying energy with each particle. We find a new neutrino contribution to the Friedmann equation resulting from the torsion term in the Ashtekar connection. In this note we explore the phenomenology of this term and observational consequences for cosmological evolution. We show that constraints on the critical energy density will ordinarily render this term unobservably small, a maximum of order $10^{-25}$ of the neutrino energy density today. However, if the time-asymmetric dark energy is tuned to cancel the cosmological constant, the torsion effect may be a dark matter candidate.

  17. Effects of asymmetric sitting on spinal balance

    Science.gov (United States)

    Woo, Hee Soon; Oh, Jong Chi; Won, Sung Yoon

    2016-01-01

    [Purpose] To investigate the effects of two common asymmetric sitting positions on spinal balance. [Subjects and Methods] Thirty-seven healthy subjects in their twenties were enrolled and randomly divided into two groups. Asymmetric positions of resting the chin on a hand and crossing the legs were performed by each group for 1 hour. After 1 hour, the subjects lay in the supine position again and spinal imbalance was measured using a device. [Results] After 1 hour of resting with the chin on a hand, sagittal imbalance, coronal imbalance, pelvic obliquity and lordosis angle presented spinal imbalance worsening of 1 hour of crossing legs, sagittal imbalance, pelvic torsion showed in mainly learned spinal imbalance living. [Conclusion] Good posture could be an innate ability, however it through habits. So this study is meaningful from the perspective of the importance of good posture. PMID:27065291

  18. Mixtures of Shifted Asymmetric Laplace Distributions

    OpenAIRE

    Franczak, Brian C.; Browne, Ryan P.; McNicholas, Paul D.

    2012-01-01

    A mixture of shifted asymmetric Laplace distributions is introduced and used for clustering and classification. A variant of the EM algorithm is developed for parameter estimation by exploiting the relationship with the general inverse Gaussian distribution. This approach is mathematically elegant and relatively computationally straightforward. Our novel mixture modelling approach is demonstrated on both simulated and real data to illustrate clustering and classification applications. In thes...

  19. New ruthenium catalysts for asymmetric hydrogenation

    OpenAIRE

    Diaz Valenzuela, Maria Belen

    2007-01-01

    A review on catalytic asymmetric hydrogenation of C=O double bonds is presented in the first chapter. Noyori’s pioneering research on ruthenium complexes containing both phosphine and diamine ligands using [i superscript]PrOH and [t superscript]BuOK is described, this system gave impressive highly chemeo-selectivity for C=O bonds and extremely high enantioselectivity for a range of acetophenone derivatives. Numerous groups have been inspired by Noyori’s catalyst of the ty...

  20. Competitive Price and Quality Under Asymmetric Information

    OpenAIRE

    Gerard J. Tellis; Birger Wernerfelt

    1987-01-01

    We present an analysis of equilibrium in markets with asymmetrically informed consumers. Some consumers know both price and quality of all sellers, whereas others know neither but may search among sellers. The equilibrium correlation between price and quality generally increases with the level of information in the market and can be negative when this level is sufficiently small. A meta-analysis of the available empirical studies strongly supports the model's predictions.

  1. Cosmological signatures of time-asymmetric gravity

    OpenAIRE

    Cortês, Marina; Liddle, Andrew R; Smolin, Lee

    2016-01-01

    We develop the model proposed by Cort\\^es, Gomes & Smolin, to predict cosmological signatures of time-asymmetric extensions of general relativity they proposed recently. Within this class of models the equation of motion of chiral fermions is modified by a torsion term. This term leads to a dispersion law for neutrinos that associates a new time-varying energy with each particle. We find a new neutrino contribution to the Friedmann equation resulting from the torsion term in the Ashtekar conn...

  2. Relative profit maximization in asymmetric oligopoly

    OpenAIRE

    Satoh, Atsuhiro; Tanaka, Yasuhito

    2014-01-01

    We analyze Bertrand and Cournot equilibria in an asymmetric oligopoly in which the firms produce differentiated substitutable goods and seek to maximize their relative profits instead of their absolute profits. Assuming linear demand functions and constant marginal costs we show the following results. If the marginal cost of a firm is lower (higher) than the average marginal cost over the industry, its output at the Bertrand equilibrium is larger (smaller) than that at the Cournot equilibrium...

  3. Asymmetric inheritance of cytoophidia in Schizosaccharomyces pombe

    OpenAIRE

    Jing Zhang; Lydia Hulme; Ji-Long Liu

    2014-01-01

    ABSTRACT A general view is that Schizosaccharomyces pombe undergoes symmetric cell division with two daughter cells inheriting equal shares of the content from the mother cell. Here we show that CTP synthase, a metabolic enzyme responsible for the de novo synthesis of the nucleotide CTP, can form filamentous cytoophidia in the cytoplasm and nucleus of S. pombe cells. Surprisingly, we observe that both cytoplasmic and nuclear cytoophidia are asymmetrically inherited during cell division. Our t...

  4. Interfacial properties of charge asymmetric ionic liquids

    OpenAIRE

    Alejandre, Jose; Bresme, Fernando; Gonzalez-Melchor, Minerva

    2009-01-01

    We report molecular dynamics simulations of the coexistence and interfacial properties of ionic liquids as a function of cation/anion, (z$_+$ : z$_-$) = (2:-1), (4:-1), charge asymmetry. Our results correct previous computations of the coexistence curve of (2:-1) charge asymmetric systems, obtained via the fine-lattice discretization method. In agreement with previous computations we report a reduction in the critical temperature and an increase in the critical density with charge asymmetry. ...

  5. Asymmetric directed polymers in random environments

    OpenAIRE

    Flores, Gregorio R. Moreno

    2010-01-01

    The model of Brownian Percolation has been introduced as an approximation of discrete last-passage percolation models close to the axis. It allowed to compute some explicit limits and prove fluctuation theorems for these, based on the relations between the Brownian percolation and random matrices. Here, we present two approaches that allow to treat discrete asymmetric models of directed polymers. In both cases, the behaviour is universal, meaning that the results do not depend on the precise ...

  6. Neuronal alignment on asymmetric textured surfaces

    OpenAIRE

    Beighley, Ross; Spedden, Elise; Sekeroglu, Koray; Atherton, Timothy; Demirel, Melik C.; Staii, Cristian

    2012-01-01

    Axonal growth and the formation of synaptic connections are key steps in the development of the nervous system. Here, we present experimental and theoretical results on axonal growth and interconnectivity in order to elucidate some of the basic rules that neuronal cells use for functional connections with one another. We demonstrate that a unidirectional nanotextured surface can bias axonal growth. We perform a systematic investigation of neuronal processes on asymmetric surfaces and quantify...

  7. On asymmetric collisions with large disruption parameters

    International Nuclear Information System (INIS)

    Collisions between a weak electron bunch and a strong positron bunch are studied within a flat model. Electrons are tracked through the transverse space charge field of the positron bunch, and it is shown that positrons in a storage ring may remain stable after asymmetric collisions with a weak electron bunch in spite of large values of the electron disruption parameter. The plasma oscillations that affect collisions with large disruption parameters may be suppressed by properly matching the electrons. 8 refs., 5 figs

  8. Asymmetric dark matter from hidden sector baryogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Dutta, Bhaskar [Department of Physics and Astronomy, Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States); Kumar, Jason, E-mail: jkumar@hawaii.edu [Department of Physics and Astronomy, University of Hawai' i, Honolulu, HI 96822 (United States)

    2011-05-23

    We consider the production of asymmetric dark matter during hidden sector baryogenesis. We consider a particular supersymmetric model where the dark matter candidate has a number density approximately equal to the baryon number density, with a mass of the same scale as the b, c and {tau}. Both baryon asymmetry and dark matter are created at the same time in this model. We describe collider and direct detection signatures of this model.

  9. Trapdoor Privacy in Asymmetric Searchable Encryption Schemes

    OpenAIRE

    Delerue Arriaga, Afonso; TANG, QIANG; Ryan, Peter

    2014-01-01

    Asymmetric searchable encryption allows searches to be carried over ciphertexts, through delegation, and by means of trapdoors issued by the owner of the data. Public Key Encryption with Keyword Search (PEKS) is a primitive with such functionality that provides delegation of exact-match searches. As it is important that ciphertexts preserve data privacy, it is also important that trapdoors do not expose the user’s search criteria. The difficulty of formalizing a security model for trapdoor pr...

  10. Asymmetric deformation of contracting human gastrocnemius muscle

    OpenAIRE

    Kinugasa, Ryuta; Hodgson, John A.; Edgerton, V. Reggie; Sinha, Shantanu

    2011-01-01

    Muscle fiber deformation is related to its cellular structure, as well as its architectural arrangement within the musculoskeletal system. While playing an important role in aponeurosis displacement, and efficiency of force transmission to the tendon, such deformation also provides important clues about the underlying mechanical structure of the muscle. We hypothesized that muscle fiber cross section would deform asymmetrically to satisfy the observed constant volume of muscle during a contra...

  11. Interfacial properties of charge asymmetric ionic liquids

    OpenAIRE

    2009-01-01

    Abstract We report molecular dynamics simulations of the coexistence and interfacial properties of ionic liquids as a function of cation/anion, (z$_+$ : z$_-$) = (2:-1), (4:-1), charge asymmetry. Our results correct previous computations of the coexistence curve of (2:-1) charge asymmetric systems, obtained via the fine-lattice discretization method. In agreement with previous computations we report a reduction in the critical temperature and an increase in the critical density wit...

  12. Do Daily Retail Gasoline Prices adjust Asymmetrically?

    OpenAIRE

    Bettendorf, Leon; Geest, Stéphanie; Kuper, G.

    2005-01-01

    This paper analyzes adjustments in the Dutch retail gasoline prices. We estimate an error correction model on changes in the daily retail price for gasoline (taxes excluded) for the period 1996-2004 taking care of volatility clustering by estimating an EGARCH model. It turns out the volatility process is asymmetrical: an unexpected increase in the producer price has a larger effect on the variance of the producer price than an unexpected decrease. We do not find evidence for amount asymmetry,...

  13. OFFICER AND COMMANDER IN ASYMMETRIC WARFARE OPERATIONS

    OpenAIRE

    Giuseppe CAFORIO

    2013-01-01

    Starting from the data of a field research conducted among soldiers with asymmetric warfare experiences from nine different countries, the author seeks to identify and shed light on the various problems that officers with command responsibilities had to face during their missions. A picture emerges of feelings and experiences relating to their first impression upon arriving in the theatre, relations with local armed forces, relations with the local population and local authorities, relations ...

  14. Dust temperatures in asymmetric prestellar cores

    OpenAIRE

    Stamatellos, D.; Whitworth, A. P.

    2004-01-01

    We present 2D Monte Carlo radiative transfer simulations of flattened prestellar cores. We argue the importance of observing prestellar cores near the peak of their emission spectra, and we point out observable characteristic features on isophotal maps of asymmetric cores at FIR wavelengths that are indicative of the cores' density and temperature structure. These features are on scales 1/5 to 1/3 of the overall core size, and so high resolution observations are needed to observe them. Finall...

  15. Prospects for Asymmetric PNe with ALMA

    CERN Document Server

    Huggins, P J

    2010-01-01

    Millimeter and sub-millimeter observations have made fundamental contributions to our current understanding of the transition from AGB stars to white dwarfs. The approaching era of ALMA brings significantly enhanced observing capabilities at these wavelengths and promises to push back the frontiers in a number of ways. We examine the scientific prospects of this new era for PNe, with an emphasis on how developments may contribute to the goals of the asymmetric PNe community.

  16. Surface segregation of conformationally asymmetric polymer blends

    OpenAIRE

    Stepanow, Semjon; Fedorenko, Andrei A.

    2005-01-01

    We have generalized the Edwards' method of collective description of dense polymer systems in terms of effective potentials to polymer blends in the presence of a surface. With this method we have studied conformationally asymmetric athermic polymer blends in the presence of a hard wall to the first order in effective potentials. For polymers with the same gyration radius $R_g$ but different statistical segment lengths $l_{A}$ and $l_{B}$ the excess concentration of stiffer polymers at the su...

  17. Legal Dilemmas in Fighting Asymmetrical Conflicts

    Directory of Open Access Journals (Sweden)

    Pnina Sharvit Baruch

    2012-04-01

    Full Text Available What legal rules apply to armed confrontations against non-state elements in areas populated by civilians? What rules apply when the enemy does not honor the basic laws of warfare - does not distinguish itself from the local population, and even uses it for shelter and as a base of operations? This essay, which presents my position on the issue, refers to such confrontations as "asymmetrical conflicts."

  18. Venture Capital Contracting Under Asymmetric Information

    OpenAIRE

    Jeffrey Trester

    1993-01-01

    The author develops a model of venture capital contracting in which the entrepreneur and venture capitalist contract under symmetric information. A condition of asymmetric information may arise subsequent to the first contract. The author shows that this condition makes debt contracts infeasible and leads to the use of preferred equity contracts. The author notes that discussions of the relation between venture capital and capital structure are rare. This paper expands the literature by addre...

  19. Applications of Chiral Anions in Asymmetric Catalysis

    OpenAIRE

    Hamilton, Gregory Lawrence

    2011-01-01

    The synthesis of molecules with control over their three-dimensional configuration, known as absolute stereochemistry, is one of the highest goals of synthetic organic chemists. As is so often the case, we strive to reach the facility and efficiency with which Nature achieves this goal. Fortunately, the chemist's imagination allows us to envision nearly unlimited possibilities for new modes of catalysis. In this dissertation, I discuss one branch of asymmetric catalysis that has in a short ti...

  20. Asymmetric Reversal in Inhomogeneous Magnetic Heterostructures

    OpenAIRE

    Li, Zhi-Pan; Petracic, Oleg; Morales, Rafael; Olamit, Justin; Batlle, Xavier; Liu, Kai; Schuller, Ivan K.

    2006-01-01

    Asymmetric magnetization reversal is an unusual phenomenon in antiferromagnet/ferromagnet (AF/FM) exchange biased bilayers. We investigated this phenomenon in a simple model system experimentally and by simulation assuming inhomogeneously distributed interfacial AF moments. The results suggest that the observed asymmetry originates from the intrinsic broken symmetry of the system, which results in local incomplete domain walls parallel to the interface in reversal to negative saturation of th...

  1. Laminar blood flow in stenotic microchannels

    OpenAIRE

    Calejo, Joana A. C.; Garcia, Valdemar; Fernandes, Carla S.

    2015-01-01

    In this work, Newtonian and non-Newtonian laminar blood flow in rectangular microchannels with symmetric and asymmetric atheroma were numerically studied. It was observed that the impact of symmetry of the atheroma is almost negligible and the non-Newtonian properties of blood leads to higher pressure drops and wall shear stresses than the ones obtained for Newtonian flows.

  2. Porous asymmetric SiO2-g-PMMA nanoparticles produced by phase inversion

    KAUST Repository

    Munirasu, Selvaraj

    2014-07-22

    A new kind of asymmetric organic-inorganic porous structure has been proposed. Asymmetric lattices of polymer grafted silica nanoparticles were manufactured by casting and phase inversion in water. Silica nanoparticles were first functionalized with 3-(dimethylethoxysilyl)propyl-2-bromoisobutyrate, followed by grafting of poly(methylmethacrylate) (PMMA) segments, performed by atom-transfer radical polymerization. Mechanically stable self-standing films were prepared by casting a dispersion of functionalized nanoparticles in different solvents and immersion in water. The resulting asymmetrically porous morphology and nanoparticle assembly was characterized by scanning electron and atomic force microscopy. The PMMA functionalized SiO2 hybrid material in acetone or acetone/dioxane led to the best-assembled structures. Porous asymmetric membranes were prepared by adding free PMMA and PMMA terminated with hydrophilic hydroxyl group. Nitrogen flow of 2800 L m-2 h -1 was measured at 1.3 bar demonstrating the porosity and potential application for membrane technology. © 2014 Springer Science+Business Media New York.

  3. Asymmetrical boundary layer separation at the base of a two cylinder geometry

    Science.gov (United States)

    Boyle, M. T.; Langston, L. S.

    1989-01-01

    This paper reports on the experimental description of the three-dimensional horseshoe vortex system occurring at the base of two cylinder mounted side by side on an endwall. The spacing between the two cylinders is adjusted to generate a family of viscous flows. Flow visualization performed in a water tunnel provides a qualitative understanding of the flow over a range of flow variables. A detailed wind tunnel experiment provides a quantitative description of the flow at a single test condition. At Re(D) = 2.5 x 10 to the 5th the measurements show an asymmetrical primary vortex with a wide flat cross section. A small counterrotating vortex is found between the primary vortex and the cylinder leading edge.

  4. Asymmetric threat data mining and knowledge discovery

    Science.gov (United States)

    Gilmore, John F.; Pagels, Michael A.; Palk, Justin

    2001-03-01

    Asymmetric threats differ from the conventional force-on- force military encounters that the Defense Department has historically been trained to engage. Terrorism by its nature is now an operational activity that is neither easily detected or countered as its very existence depends on small covert attacks exploiting the element of surprise. But terrorism does have defined forms, motivations, tactics and organizational structure. Exploiting a terrorism taxonomy provides the opportunity to discover and assess knowledge of terrorist operations. This paper describes the Asymmetric Threat Terrorist Assessment, Countering, and Knowledge (ATTACK) system. ATTACK has been developed to (a) data mine open source intelligence (OSINT) information from web-based newspaper sources, video news web casts, and actual terrorist web sites, (b) evaluate this information against a terrorism taxonomy, (c) exploit country/region specific social, economic, political, and religious knowledge, and (d) discover and predict potential terrorist activities and association links. Details of the asymmetric threat structure and the ATTACK system architecture are presented with results of an actual terrorist data mining and knowledge discovery test case shown.

  5. Multiple Traveling Salesmen in Asymmetric Metrics

    CERN Document Server

    Friggstad, Zachary

    2011-01-01

    We consider some generalizations of the Asymmetric Traveling Salesman Path problem. Suppose we have an asymmetric metric G = (V,A) with two distinguished nodes s,t. We are also given a positive integer k. The goal is to find k paths of minimum total cost from s to t whose union spans all nodes. We call this the k-Person Asymmetric Traveling Salesmen Path problem (k-ATSPP). Our main result for k-ATSPP is a bicriteria approximation that, for some parameter b >= 1 we may choose, finds between k and k + k/b paths of total length O(b log |V|) times the optimum value of an LP relaxation based on the Held-Karp relaxation for the Traveling Salesman problem. On one extreme this is an O(log |V|)-approximation that uses up to 2k paths and on the other it is an O(k log |V|)-approximation that uses exactly k paths. Next, we consider the case where we have k pairs of nodes (s_1,t_1), ..., (s_k,t_k). The goal is to find an s_i-t_i path for every pair such that each node of G lies on at least one of these paths. Simple appro...

  6. Asymmetric Conditional Volatility in International Stock Markets

    CERN Document Server

    Ferreira, N B; Menezes, R; Ferreira, Nuno B.; Mendes, Diana A.; Menezes, Rui

    2006-01-01

    Recent studies show that a negative shock in stock prices will generate more volatility than a positive shock of similar magnitude. The aim of this paper is to appraise the hypothesis under which the conditional mean and the conditional variance of stock returns are asymmetric functions of past information. We compare the results for the Portuguese Stock Market Index PSI 20 with six other Stock Market Indices, namely the S&P 500, FTSE100, DAX 30, CAC 40, ASE 20, and IBEX 35. In order to assess asymmetric volatility we use autoregressive conditional heteroskedasticity specifications known as TARCH and EGARCH. We also test for asymmetry after controlling for the effect of macroeconomic factors on stock market returns using TAR and M-TAR specifications within a VAR framework. Our results show that the conditional variance is an asymmetric function of past innovations raising proportionately more during market declines, a phenomenon known as the leverage effect. However, when we control for the effect of chan...

  7. Research on Pressure Jump Characteristics of Valve Controlled Asymmetric Cylinder System

    Directory of Open Access Journals (Sweden)

    Guo Ji-chang

    2014-03-01

    Full Text Available The study introduces a method which can eliminate pressure jump when asymmetrical cylinder is moves backward. It shares the flow of the cylinder non-rod end chamber by auxiliary servo valve to guarantee symmetrical flow of main servo valve. The paper gives an overview of the program principles, theoretical analysis and calculation; at last, it makes simulation based on software of AMESim. Results show that this method can eliminate pressure jump of cylinder when moves backward. This method can bring new applications to engineering practical value.

  8. Cylindrical Asymmetrical Capacitors for Use in Outer Space

    Science.gov (United States)

    Campbell, Jonathan W.

    2007-01-01

    A report proposes that cylindrical asymmetrical capacitors (CACs) be used to generate small thrusts for precise maneuvering of spacecraft on long missions. The report notes that it has been known for decades that when high voltages are applied to CACs in air, thrusts are generated - most likely as a result of ionization of air molecules and acceleration of the ions by the high electric fields. The report goes on to discuss how to optimize the designs of CACs for operation as thrusters in outer space. Components that could be used to enable outerspace operation include a supply of gas and a shroud, partly surrounding a CAC, into which the gas would flow. Other elements of operation and design discussed in the report include variation of applied voltage and/or of gas flow to vary thrust, effects of CAC and shroud dimensions on thrust and weight, some representative electrode configurations, and several alternative designs, including one in which the basic CAC configuration would be modified into something shaped like a conventional rocket engine with converging/diverging nozzle and an anode with gas feed in the space that, in a conventional rocket engine, would be the combustion chamber.

  9. Optical diagnostics of intermittent flows

    DEFF Research Database (Denmark)

    Okulov, V.L.; Naumov, I.V.; Sørensen, Jens Nørkær

    2007-01-01

    image velocimetry, frequently give erroneous results, especially for the transition flow and developed nonstationary flow. However, their combined use in diagnostics of unsteady (intermittent) flows significantly improves both the temporal and spatial resolution of measurements. Such a complex approach......The efficiency of combined use of different optical techniques for flow diagnostics is demonstrated with the practically important case of intense swirling flows. It is shown that, when applied separately, commonly used optical measuring techniques, such as laser Doppler anemometry and particle...... is for the first time applied for diagnostics of the flow pattern in a closed cylinder with a rotating end face with the aim of studying the changeover from the steady axisymmetric to unsteady asymmetric flow over a wide range of flow parameters. It is found that such a transition is notable for...

  10. Numerical Solution of the Asymmetric Water Impact of A Wedge in Three Degrees of Freedom

    Institute of Scientific and Technical Information of China (English)

    H.Ghazizade-Ahsaee; A.H.Nikseresht

    2013-01-01

    Impact problems associated with water entry have important applications in various aspects of naval architecture and ocean engineering.Estimation of hydrodynamic impact forces especially during the first instances after the impact is very important and is of interest.Since the estimation of hydrodynamic impact load plays an important role in safe design and also in evaluation of structural weight and costs,it is better to use a reliable and accurate prediction method instead of a simple estimation resulted by analyzing methods.In landing of flying boats,some phenomena such as weather conditions and strong winds can cause asymmetric instead of symmetric descent.In this paper,a numerical simulation of the asymmetric impact of a wedge,as the step of a flying boat,considering dynamic equations in two-phase flow is taken into account.The dynamic motion of the wedge in two-phase flow is solved based on finite volume method with volume of fluid (VOF) scheme considering dynamic equations.Then the effects of different angles of impact and water depth on the velocity change and slamming forces in an asymmetric impact are investigated.The comparison between the simulation results and experimental data verifies the accuracy of the method applied in the present study.

  11. Numerical solution of the asymmetric water impact of a wedge in three degrees of freedom

    Science.gov (United States)

    Ghazizade-Ahsaee, H.; Nikseresht, A. H.

    2013-06-01

    Impact problems associated with water entry have important applications in various aspects of naval architecture and ocean engineering. Estimation of hydrodynamic impact forces especially during the first instances after the impact is very important and is of interest. Since the estimation of hydrodynamic impact load plays an important role in safe design and also in evaluation of structural weight and costs, it is better to use a reliable and accurate prediction method instead of a simple estimation resulted by analyzing methods. In landing of flying boats, some phenomena such as weather conditions and strong winds can cause asymmetric instead of symmetric descent. In this paper, a numerical simulation of the asymmetric impact of a wedge, as the step of a flying boat, considering dynamic equations in two-phase flow is taken into account. The dynamic motion of the wedge in two-phase flow is solved based on finite volume method with volume of fluid (VOF) scheme considering dynamic equations. Then the effects of different angles of impact and water depth on the velocity change and slamming forces in an asymmetric impact are investigated. The comparison between the simulation results and experimental data verifies the accuracy of the method applied in the present study.

  12. Nanotribology of Symmetric and Asymmetric Liquid Lubricants

    Directory of Open Access Journals (Sweden)

    Shinji Yamada

    2010-03-01

    Full Text Available When liquid molecules are confined in a narrow gap between smooth surfaces, their dynamic properties are completely different from those of the bulk. The molecular motions are highly restricted and the system exhibits solid-like responses when sheared slowly. This solidification behavior is very dependent on the molecular geometry (shape of liquids because the solidification is induced by the packing of molecules into ordered structures in confinement. This paper reviews the measurements of confined structures and friction of symmetric and asymmetric liquid lubricants using the surface forces apparatus. The results show subtle and complex friction mechanisms at the molecular scale.

  13. Analysis of Asymmetric Piezoelectric Composite Beam

    CERN Document Server

    Chen, J -S; Wu, K -C

    2008-01-01

    This paper deals with the vibration analysis of an asymmetric composite beam composed of glass a piezoelectric material. The Bernoulli's beam theory is adopted for mechanical deformations, and the electric potential field of the piezoelectric material is assumed such that the divergence-free requirement of the electrical displacements is satisfied. The accuracy of the analytic model is assessed by comparing the resonance frequencies obtained by the analytic model with those obtained by the finite element method. The model developed can be used as a tool for designing piezoelectric actuators such as micro-pumps.

  14. On asymmetric causal relationships in Petropolitics

    Directory of Open Access Journals (Sweden)

    Balan Feyza

    2016-01-01

    Full Text Available The aim of this paper is to examine whether the First Law of Petropolitics denominated by Friedman in 2006 is valid for OPEC countries. To do this, this paper analyses the relationship between political risk and oil supply by applying the asymmetric panel causality test suggested by Hatemi-J (2011 to these countries for the period 1984-2014. The results show that the First Law of Petropolitics is valid for Angola, Iraq, Kuwait, Libya, Nigeria, Qatar, Saudi Arabia, and the UAE, given that positive oil supply shocks significantly lead to negative political stability shocks, and negative oil supply shocks significantly lead to positive shocks in political stability.

  15. RHIC operation with asymmetric collisions in 2015

    Energy Technology Data Exchange (ETDEWEB)

    Liu, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Aschenauer, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Atoian, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); Blaskiewicz, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Brown, K. A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Bruno, D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Connolly, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ottavio, T. D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Drees, K. A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Fischer, W. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gardner, C. J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gu, X. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hayes, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Huang, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Laster, J. S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Luo, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Makdisi, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Marr, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); Marusic, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Meot, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Mernick, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Michnoff, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Minty, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Montag, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Morris, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Narayan, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); Nayak, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Nemesure, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Pile, P. [Brookhaven National Lab. (BNL), Upton, NY (United States); Poblaguev, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ranjbar, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Robert-Demolaize, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); Roser, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Schmidke, B. [Brookhaven National Lab. (BNL), Upton, NY (United States); Schoefer, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Severino, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Shrey, T. [Brookhaven National Lab. (BNL), Upton, NY (United States); Smith, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Steski, D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tepikian, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Trbojevic, D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tsoupas, N. [Brookhaven National Lab. (BNL), Upton, NY (United States); Wang, G. [Brookhaven National Lab. (BNL), Upton, NY (United States); White, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Yip, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zaltsman, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zhang, S. Y. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-08-07

    To study low-x shadowing/saturation physics as well as other nuclear effects [1], [2], proton-gold (p-Au, for 5 weeks) and proton-Aluminum (p-Al, for 2 weeks) collisions were provided for experiments in 2015 at the Relativistic Heavy Ion Collider (RHIC), with polarized proton beam in the Blue ring and Au/Al beam in the Yellow ring. The special features of the asymmetric run in 2015 will be introduced. The operation experience will be reviewed as well in the report.

  16. OFFICER AND COMMANDER IN ASYMMETRIC WARFARE OPERATIONS

    Directory of Open Access Journals (Sweden)

    Giuseppe CAFORIO

    2013-01-01

    Full Text Available Starting from the data of a field research conducted among soldiers with asymmetric warfare experiences from nine different countries, the author seeks to identify and shed light on the various problems that officers with command responsibilities had to face during their missions. A picture emerges of feelings and experiences relating to their first impression upon arriving in the theatre, relations with local armed forces, relations with the local population and local authorities, relations with NGOs, relations with other armies, the impact of the rules of engagement (ROEs, training and education, and operational experiences. The paper ends with a discussion of the lessons learned.

  17. Asymmetric catalytic aziridination of cyclic enones.

    Science.gov (United States)

    De Vincentiis, Francesco; Bencivenni, Giorgio; Pesciaioli, Fabio; Mazzanti, Andrea; Bartoli, Giuseppe; Galzerano, Patrizia; Melchiorre, Paolo

    2010-07-01

    The first catalytic method for the asymmetric aziridination of cyclic enones is described. The presented organocatalytic strategy is based on the use of an easily available organocatalyst that is able to convert a wide range of cyclic enones into the desired aziridines with very high enantiomeric purity and good chemical yield. Such a method may very well open up new opportunities to stereoselectively prepare complex chiral molecules that possess an indane moiety, a framework that is found in a large number of bioactive and pharmaceutically important molecules. PMID:20512797

  18. Plasmonic photodetectors based on asymmetric nanogap electrodes

    Science.gov (United States)

    Ge, Junyu; Luo, Manlin; Zou, Wanghui; Peng, Wei; Duan, Huigao

    2016-08-01

    Hot electrons excited by plasmon resonance in nanostructure can be employed to enhance the properties of photodetectors, even when the photon energy is lower than the bandgap of the semiconductor. However, current research has seldom considered how to realize the efficient collection of hot electrons, which restricts the responsivity of the device. In this paper, a type of plasmonic photodetector based on asymmetric nanogap electrodes is proposed. Owing to this structure, the device achieves responsivities as high as 0.45 and 0.25 mA/W for wavelengths of 1310 and 1550 nm, respectively. These insights can aid the realization of efficient plasmon-enhanced photodetectors for infrared detection.

  19. Governor model for asymmetric deformed nuclei

    International Nuclear Information System (INIS)

    The governor model is extended to include the asymmetric shape of nuclei which allows a simultaneous analysis of the data for both the ground state and the γ-vibrational bands in deformed even-even nuclei. The rotationally invariant core is assumed to be a spheroid with an axis of symmetry parallel to the axis of rotation. The calculations are carried out under the assumption of no stretching. The static γ-deformation results are compared with the VMI(ARM) and Krutov values, and the calculated energies are in good agreement with the experimental data

  20. Plasma current resonance in asymmetric toroidal systems

    Energy Technology Data Exchange (ETDEWEB)

    Hazeltine, R. D. [Institute for Fusion Studies, University of Texas at Austin, Austin, Texas 78712 (United States); Catto, Peter J. [Plasma Science and Fusion Center, Massachusetts Institute of Technology, 167 Albany Street, Cambridge, Massachusetts 02139 (United States)

    2015-09-15

    The well-known singularity in the magnetic differential equation for plasma current in an asymmetric toroidal confinement system is resolved by including in the pressure tensor corrections stemming from finite Larmor radius. The result provides an estimate of the amplitude of spikes in the parallel current that occur on rational magnetic surfaces. Resolution of the singularity is shown to depend on both the ambipolarity condition—the requirement of zero surface-averaged radial current—and the form of the magnetic differential equation near the rational surface.