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Sample records for astrophytum myriostigma lemaire

  1. Morfometría de semillas en la cactácea amenazada de extinción Astrophytum myriostigma Lemaire

    Directory of Open Access Journals (Sweden)

    Jaime Sánchez-Salas

    2015-07-01

    Full Text Available Se presenta un estudio morfométrico y microestructural en semillas de una población de la cactácea amenazadaAstrophytum myriostigmaLem., removida en su tota- lidad en el sitio por saqueo. Se incluyen resultados que separan tamaños de semillas y embriones (grandes y pequeños así como promedios para ambos. Se realizó una descripción de características en la semilla obtenidas mediante estereoscopía. Se incluye una descripción detallada de la forma y color, así como microestructural del funículo, capa funicular y otras estructuras que le acompañan.

  2. A tale of two cacti-the complex relationship between peyote (Lophophora williamsii) and endangered star cactus (Astrophytum asterias)

    Science.gov (United States)

    M. Terry; D. Price; J. Poole

    2007-01-01

    Astrophytum asterias, commonly called star cactus, is a federally listed endangered cactus endemic to the Tamaulipan thornscrub ecoregion of extreme southern Texas, USA, and Tamaulipas and Nuevo Leon, Mexico. Only three metapopulations totaling less than 4000 plants are presently known in Texas. Star cactus, known locally as “star peyote”, is highly...

  3. Hypoglycemic effect of Opuntia streptacantha Lemaire in NIDDM.

    Science.gov (United States)

    Frati-Munari, A C; Gordillo, B E; Altamirano, P; Ariza, C R

    1988-01-01

    To assess the hypoglycemic effect of the nopal Opuntia streptacantha Lemaire (O. streptacantha Lem.), three groups of patients with non-insulin-dependent diabetes mellitus (NIDDM) were studied. Group one (16 patients) ingested 500 g of broiled nopal stems. Group 2 (10 patients) received only 400 ml of water as a control test. Three tests were performed on group 3 (6 patients): one with nopal, a second with water, and a third with ingestion of 500 g broiled squash. Serum glucose and insulin levels were measured at 0, 60, 120, and 180 min. After the intake of O. streptacantha Lem., serum glucose and serum insulin levels decreased significantly in groups 1 and 3, whereas no similar changes were noticed in group 2. The mean reduction of glucose reached 17.6 +/- 2.2% of basal values at 180 min in group 1 and 16.2 +/- 1.8% in group 3; the reduction of serum insulin at 180 min reached 50.2 +/- 8.0% in group 1 and 40.3 +/- 12.4% in group 3. This study shows that the stems of O. streptacantha Lem. cause a hypoglycemic effect in patients with NIDDM. The mechanism of this effect is unknown, but an increased insulin sensitivity is suggested.

  4. Anatomical and morphological features of seedlings of some Cactoideae Eaton (Cactaceae Juss. species

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    Halyna Kalashnyk

    2016-12-01

    Full Text Available Three-month-old seedlings of 11 species of the subfamily Cactoideae (Melocactus bahiensis, Melocactus curvispinus, Echinopsis eyriesii, E. mirablis, E. peruviana, Oreocereus celsianus, Rebutia flavistyla, Rebutia minuscula, Astrophytum myriostigma, Mamillaria columbiana, and M. prolifera have been studied. These plants exhibit a uniseriate epidermis, covered by a thin cuticle. Except for E. peruviana and A. myriostigma, no hypodermis could be detected. The shoots of all studied specimens consist mainly of cortex parenchyma with large thin-walled cells. The pith parenchyma is composed of much smaller cells. Due to the fact that the cortex parenchyma comprises the largest portion of the cross-sectional area, it can be concluded that it is the main water-storing tissue. The extent of vascular tissue development varies. Collateral vascular bundles are present in the stele. The studied seedlings contain various ergastic substances, in particular inclusions of calcium oxalate (all studied species, starch (Mammillaria prolifera, E. mirabilis, and the genus Melocactus, inulin-like inclusions, and occasionally lipid drops (some Echinopsis species. Thus, it was found that all studied plants have a highly specialized anatomical and morphological structure. At the same time, the epidermis and hypodermis are poorly developed. Accordingly, the adaptation to arid conditions of the examined seedlings involves an increased growth of the water-storing tissue and the production of ergastic substances.

  5. [Hypoglycemic action of different doses of nopal (Opuntia streptacantha Lemaire) in patients with type II diabetes mellitus].

    Science.gov (United States)

    Frati-Munari, A C; Del Valle-Martínez, L M; Ariza-Andraca, C R; Islas-Andrade, S; Chávez-Negrete, A

    1989-01-01

    To assess the relationship between the doses of O. streptacantha Lem. and its acute hypoglycemic action in diabetics, eight patients with type II diabetes mellitus were studied. Four test were performed to each patient with the intake of: (a) 400 ml of water, (b) 100 g (c) 300 g and (d) 500 g of broiled stems of O. streptacantha Lem. Serum glucose was measured at 0, 60, 120 and 180 minutes. Maximal decrease of serum glucose was noticed at 180 minutes, with a mean of 2.3, 10, 30.1 and 46.7 mg/dl less than basal value with 0, 100, 300 and 500 g respectively (P = NS, less than 0.05, less than 0.001 and less than 0.001 respectively). A significant direct correlation (r = 0.690, P less than 0.001) was noticed between the doses and the hypoglycemic effect.

  6. Descripción de la hembra de Copaxa ignescens (Lepidoptera: Saturniidae, con anotaciones sobre sus primeros estadios inmaduros

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    Amarillo S. Angela R.

    1997-06-01

    Full Text Available The female of Copaxa ignescens Lemaire, 1978 (Saturniidae is described and notes on the first three larval instars are presented. The caterpillars were reared on Avocado (Persea americana Miller.Se describe la hembra de Copaxa ignescens Lemaire, 1978 (Saturniidae y se hacen anotaciones sobre los tres primeros estadios larvales. Las orugas se criaron con Aguacate (Persaa americana Miller.

  7. 50 CFR 17.12 - Endangered and threatened plants.

    Science.gov (United States)

    2010-10-01

    ... 343 NA NA Ancistrocactus tobuschii Tobusch fishhook cactus U.S.A. (TX) Cactaceae E 80 NA NA Apios... ......do E 647 NA NA Astrophytum asterias Star cactus U.S.A. (TX), Mexico Cactaceae E 521 NA NA Atriplex...) Cactaceae E 208 NA NA Chamaecrista glandulosa var. mirabilis None U.S.A. (PR) Fabaceae E 379 NA NA...

  8. Maailma kuulsaim krokodill sai 75 aastaseks / Anu Merila

    Index Scriptorium Estoniae

    Merila, Anu

    2008-01-01

    Lacoste'i sportlikke rõivaid ja aksessuaare tootvast kaubamärgist, asutaja Rene Lacoste. Firma loominguliseks direktoriks on prantsuse moekunstnik Christophe Lemaire. Küsimustele vastab Philippe Lacoste

  9. Synthesis and influence of alkaline concentration on α-FeOOH ...

    Indian Academy of Sciences (India)

    Administrator

    pH values of solution play an important role in the process of transformation of ... largely dependent on their size, shape and surface chemistry. (Tang et al 2006; ... (Lemaire et al 2002), sensors (Chen et al 2005) and min- eral liquid crystals ...

  10. Pre-release efficacy assessment of the leaf-mining moth Digitivalva delaireae (Lepidoptera: Glyphipterigidae), a potential biological control agent for Cape-ivy, Delairea odorata (Asteraceae), in western North America

    Science.gov (United States)

    The leaf-mining moth Digitivalva delaireae Gaedike & Kruger (Lepidoptera: Glyphipterigidae) is a potential biological control agent for the invasive vine Cape-ivy, Delairea odorata Lemaire (Asteraceae), in western North America, where two morphological varieties (stipulate and exstipulate) of Cape-i...

  11. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 8. Differential Scanning Calorimetry: Fundamental Overview. Kevin Lukas Peter K LeMaire. Classroom Volume 14 Issue 8 August 2009 pp 807-817. Fulltext. Click here to view fulltext PDF. Permanent link:

  12. Hypoglycemic effect of Opuntia cactus.

    Science.gov (United States)

    Ibañez-Camacho, R; Roman-Ramos, R

    1979-01-01

    Nopal (Opuntia sp.) has been traditionally used by the Mexican population for the treatment of diabetes mellitus. The purpose of this work is to describe effects produced by directly liquified nopal and extracts from this plant in healthy and pancreatectomized rabbits. Preliminary results allow us to conclude that Opuntia streptacantha, Lemaire, has hypoglycemic properties when orally administered, in animals with experimentally induced diabetes as well as in healthy ones with physiologic hyperglycemia.

  13. Distributed Hybrid Information and Plan Consensus HIPC for Semi-autonomous UAV Teams

    Science.gov (United States)

    2015-09-18

    furniture may move around a bit on a daily basis, 2) workers in different parts of the building may stay later on some nights forcing a delay in entering...systems. International Journal of Robotics Research, 23(9):939–954, 2004. [17] M. B. Dias, R. Zlot, N. Kalra, and A. Stentz. Market -based multirobot...free market auctions to distribute control of UAVs. In AIAA 3rd Unmanned Unlimited Technical Conference, Workshop and Exhibit, 2004. [34] T. Lemaire

  14. Modeling Saturn's Inner Plasmasphere: Cassini's Closest Approach

    Science.gov (United States)

    Moore, L.; Mendillo, M.

    2005-05-01

    Ion densities from the three-dimensional Saturn-Thermosphere-Ionosphere-Model (STIM, Moore et al., 2004) are extended above the plasma exobase using the formalism of Pierrard and Lemaire (1996, 1998), which evaluates the balance of gravitational, centrifugal and electric forces on the plasma. The parameter space of low-energy ionospheric contributions to Saturn's plasmasphere is explored by comparing results that span the observed extremes of plasma temperature, 650 K to 1700 K, and a range of velocity distributions, Lorentzian (or Kappa) to Maxwellian. Calculations are made for plasma densities along the path of the Cassini spacecraft's orbital insertion on 1 July 2004. These calculations neglect any ring or satellite sources of plasma, which are most likely minor contributors at 1.3 Saturn radii. Modeled densities will be compared with Cassini measurements as they become available. Moore, L.E., M. Mendillo, I.C.F. Mueller-Wodarg, and D.L. Murr, Icarus, 172, 503-520, 2004. Pierrard, V. and J. Lemaire, J. Geophys. Res., 101, 7923-7934, 1996. Pierrard, V. and J. Lemaire, J. Geophys. Res., 103, 4117, 1998.

  15. Extra-Articular Lateral Tenodesis for Anterior Cruciate Ligament Deficient Knee: A Case Report

    Science.gov (United States)

    García-Germán, Diego; Menéndez, Pablo; de la Cuadra, Pablo; Rodríguez-Arozena, Ricardo

    2013-01-01

    We present the case of an extra-articular lateral tenodesis for an anterior cruciate ligament (ACL) deficient knee. A 46-year-old male patient sustained an ACL graft rupture after a motorcycle accident. He complained of rotational instability and giving-way episodes. His previous graft was fixed by an intra-articular femoral staple that was not possible to remove at the time of the ACL revision. A modified Lemaire procedure was then performed. He gained rotational stability and was able to resume his sporting activities. We believe that isolated extra-articular reconstructions may still have a role in selected indications including moderate-demand patients complaining of rotational instability after ACL graft failure. PMID:24369517

  16. Geophysical and solar activity indices

    Science.gov (United States)

    Bossy, L.; Lemaire, J.

    1984-04-01

    A large number of geophysicists try to correlate their observations with one or even a series of different geophysical or solar activity indices. Yet the right choice of the most appropriate index with which to correlate depends mainly on our understanding of the physical cause-effect relationship between the new set of observations and the index chosen. This best choice will therefore depend on our good understanding of the methods of measurement and derivation of the adopted index in such correlative studies. It relies also on our awareness of the range of applicability of the indices presently available as well as on our understanding of their limitations. It was to achieve these goals that a series of general lectures on geophysical and solar activity indices was organized by L. Bossy and J. Lemaire (Institut d'Aeronomie Spatiale de Belgique (IASB), Brussels), March 26-29, 1984 at Han-sur-Lesse, Belgium.

  17. Extra-Articular Lateral Tenodesis for Anterior Cruciate Ligament Deficient Knee: A Case Report

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    Diego García-Germán

    2013-01-01

    Full Text Available We present the case of an extra-articular lateral tenodesis for an anterior cruciate ligament (ACL deficient knee. A 46-year-old male patient sustained an ACL graft rupture after a motorcycle accident. He complained of rotational instability and giving-way episodes. His previous graft was fixed by an intra-articular femoral staple that was not possible to remove at the time of the ACL revision. A modified Lemaire procedure was then performed. He gained rotational stability and was able to resume his sporting activities. We believe that isolated extra-articular reconstructions may still have a role in selected indications including moderate-demand patients complaining of rotational instability after ACL graft failure.

  18. First-Order Twistor Lifts

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    Simões BrunoAscenso

    2010-01-01

    Full Text Available The use of twistor methods in the study of Jacobi fields has proved quite fruitful, leading to a series of results. L. Lemaire and J. C. Wood proved several properties of Jacobi fields along harmonic maps from the two-sphere to the complex projective plane and to the three- and four-dimensional spheres, by carefully relating the infinitesimal deformations of the harmonic maps to those of the holomorphic data describing them. In order to advance this programme, we prove a series of relations between infinitesimal properties of the map and those of its twistor lift. Namely, we prove that isotropy and harmonicity to first order of the map correspond to holomorphicity to first order of its lift into the twistor space, relatively to the standard almost complex structures and . This is done by obtaining first-order analogues of classical twistorial constructions.

  19. First-Order Twistor Lifts

    Directory of Open Access Journals (Sweden)

    Bruno Ascenso Simões

    2010-01-01

    Full Text Available The use of twistor methods in the study of Jacobi fields has proved quite fruitful, leading to a series of results. L. Lemaire and J. C. Wood proved several properties of Jacobi fields along harmonic maps from the two-sphere to the complex projective plane and to the three- and four-dimensional spheres, by carefully relating the infinitesimal deformations of the harmonic maps to those of the holomorphic data describing them. In order to advance this programme, we prove a series of relations between infinitesimal properties of the map and those of its twistor lift. Namely, we prove that isotropy and harmonicity to first order of the map correspond to holomorphicity to first order of its lift into the twistor space, relatively to the standard almost complex structures J1 and J2. This is done by obtaining first-order analogues of classical twistorial constructions.

  20. Patients With Ligament Hiperlaxity With Rupture Of Previous Plastic For ACL. Reconstruction With Intra-articular And Extra-articular Combined Technics

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    Astore, Ignacio; Agotegaray, Juan Ignacio; Comba, Ignacio; Bisiach, Luciana

    2017-01-01

    Introduction: In cases of patients with ligament hiperlaxity with rupture of ACL, the use of a BTB graft is recommended for its reconstruction. Our job consists of the clinical and functional assessment of a group of 10 patients with ligament laxaty according to Beighton scale, who, after surgery for ACL rupture with BTB technique, suffered a rupture of the plastic. For its reconstruction a combination of intra-articular and extra-articular techniques was used with a BTB graft in the contralateral knee, associated with a modified Lemaire technique. Methods: The series consists of 10 patients, male, average age of 24.2 years, amateur athletes, operated for a second time in March, 2011 and November, 2013, with a minimum follow-up of 24 months. They were evaluated before surgery and 24 months after surgery based on Lysholm scale, IKDC evaluation form and a physical exam (Lachman - Pivot Shift). Results: After surgery, the average in Lysholm scale was of 87.6 and 86.3 for the IKDC subjetive form. In the physical exam, 8 patients showed Lachman 1+, while none of the patients showed Pivot Shift positive. 7 patients were able to return to their usual sport activities. As a postoperative disadvantage, 6 patients reported pain in the external face of the knee in the first 6 months. And 4 patients reported a subjetive loss of full extension that did not interfere with their sport activities. Conclusion: Based on our experience and literature, we believe that the combination of both techniques, intra-articular (BTB) and extra-articular (Lemaire), is a good alternative for patients with ligament laxaty, providing positive clinical and functional results.

  1. Cytophotometric and biochemical analyses of DNA in pentaploid and diploid Agave species.

    Science.gov (United States)

    Cavallini, A; Natali, L; Cionini, G; Castorena-Sanchez, I

    1996-04-01

    Nuclear DNA content, chromatin structure, and DNA composition were investigated in four Agave species: two diploid, Agave tequilana Weber and Agave angustifolia Haworth var. marginata Hort., and two pentaploid, Agave fourcroydes Lemaire and Agave sisalana Perrine. It was determined that the genome size of pentaploid species is nearly 2.5 times that of diploid ones. Cytophotometric analyses of chromatin structure were performed following Feulgen or DAPI staining to determine optical density profiles of interphase nuclei. Pentaploid species showed higher frequencies of condensed chromatin (heterochromatin) than diploid species. On the other hand, a lower frequency of A-T rich (DAPI stained) heterochromatin was found in pentaploid species than in diploid ones, indicating that heterochromatin in pentaploid species is made up of sequences with base compositions different from those of diploid species. Since thermal denaturation profiles of extracted DNA showed minor variations in the base composition of the genomes of the four species, it is supposed that, in pentaploid species, the large heterochromatin content is not due to an overrepresentation of G-C repetitive sequences but rather to the condensation of nonrepetitive sequences, such as, for example, redundant gene copies switched off in the polyploid complement. It is suggested that speciation in the genus Agave occurs through point mutations and minor DNA rearrangements, as is also indicated by the relative stability of the karyotype of this genus. Key words : Agave, DNA cytophotometry, DNA melting profiles, chromatin structure, genome size.

  2. Connecting World Heritage Nominations and Monitoring with the Support of the Silk Roads Cultural Heritage Resource Information System

    Science.gov (United States)

    Vileikis, O.; Dumont, B.; Serruys, E.; Van Balen, K.; Tigny, V.; De Maeyer, P.

    2013-07-01

    Serial transnational World Heritage nominations are challenging the way cultural heritage has been managed and evaluated in the past. Serial transnational World Heritage nominations are unique in that they consist of multiple sites listed as one property, distributed in different countries, involving a large diversity of stakeholders in the process. As a result, there is a need for precise baseline information for monitoring, reporting and decision making. This type of nomination requires different methodologies and tools to improve the monitoring cycle from the beginning of the nomination towards the periodic reporting. The case study of the Silk Roads Cultural Heritage Resource Information System (CHRIS) illustrates the use of a Geographical Content Management System (Geo-CMS) supporting the serial transnational World Heritage nomination and the monitoring of the Silk Roads in the five Central Asian countries. The Silk Roads CHRIS is an initiative supported by UNESCO World Heritage Centre (WHC) and the Belgian Federal Science Policy Office (BELSPO), and developed by a consortium headed by the Raymond Lemaire International Centre for Conservation (RLICC) at the KULeuven. The Silk Roads CHRIS has been successfully assisting in the preparation of the nomination dossiers of the Republics of Kazakhstan, Tajikistan and Uzbekistan and will be used as a tool for monitoring tool in the Central Asian countries.

  3. Raman Spectroscopy of Serpentine and Reaction Products at High Pressure Using a Diamond Anvil Cell

    Science.gov (United States)

    Burgess, K.; Zinin, P.; Odake, S.; Fryer, P.; Hellebrand, E.

    2012-12-01

    Serpentine is one of the most abundant hydrous phases in the altered subducting plate, and contributes a large portion of the water flux in subduction zones. Measuring and understanding the structural changes in serpentine with pressure aids our understanding of the processes ongoing in oceanic crust and subduction zones. We have conducted high-pressure/high-temperature experiments on serpentine and its dehydration reaction products using a diamond anvil cell. We used the multifunctional in-situ measurement system equipped with a Raman device and laser heating system at the University of Hawaii. Well-characterized natural serpentinite was used in the study. Pressure was determined using the shift of the fluorescence line of a ruby placed next to the sample. Raman spectra of serpentine were obtained at higher pressures than previously published, up to 15 GPa; the peak shift with pressure fits the model determined by Auzende et al. [2004] at lower pressures. Heating was done at several different pressures up to 20 GPa, and reaction products were identified using Raman. Micro-Raman techniques allow us to determine reaction progress and heterogeneity within natural samples containing olivine and serpentine. Auzende, A-L., I. Daniel, B. Reynard, C. Lemaire, F. Guyot (2004). High-pressure behavior of serpentine minerals: a Raman spectroscopic study. Phys. Chem. Minerals 31 269-277.

  4. Amomum tsao-ko suppresses lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages via Nrf2-dependent heme oxygenase-1 expression.

    Science.gov (United States)

    Li, Bin; Choi, Hee-Jin; Lee, Dong-Sung; Oh, Hyuncheol; Kim, Youn-Chul; Moon, Jin-Young; Park, Won-Hwan; Park, Sun-Dong; Kim, Jai-Eun

    2014-01-01

    Amomum tsao-ko Crevost et Lemaire, used as a spice in Asia, is an important source of Chinese cuisine and traditional Chinese medicines. A. tsao-ko is reported to exert a variety of biological and pharmacological activities, including anti-proliferative, anti-oxidative and neuroprotective effects. In this study, NNMBS227, consisting of the ethanol extract of A. tsao-ko, exhibited potent anti-inflammatory activities in RAW264.7 macrophages. We investigated the effect of NNMBS227 in the suppression of pro-inflammatory mediators, including pro-inflammatory enzymes (inducible nitric oxide synthase and cyclooxygenase-2) and cytokines (tumor necrosis factor-α and interleukin-1β) in LPS stimulated macrophages. NNMBS227 also inhibited the phosphorylation and degradation of IκB-α, as well as the nuclear translocation of nuclear factor kappa B (NF-κB) p65 caused by stimulation with LPS. In addition, NNMBS227 induced heme oxygenase (HO)-1 expression through the nuclear translocation of nuclear factor E2-related factor 2 (Nrf2) in macrophages. Using tin protoporphyrin (SnPP), an HO activity inhibitor, we confirmed an association between the anti-inflammatory effects of NNMBS227 and the up-regulation of HO-1. These findings suggest that Nrf2-dependent increases in the expression of HO-1 induced by NNMBS227 conferred anti-inflammatory activities in LPS stimulated RAW264.7 macrophages.

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    James F. Weiner

    1988-10-01

    Full Text Available - A.P. Borsboom, Fredrik Barth, Cosmologies in the making; A generative approach to cultural variation in Inner New Guinea, Cambridge studies in social anthropology, Cambridge University Press, 1987, 99 pp., - H.J.M. Claessen, Paul van der Grijp, Sporen in de Antropologie; Liber Amicorum voor Jan Pouwer, Nijmegen: Instituut voor Kulturele en Sociale Antropologie, 1987. Bibl., tab., ill. 330 pp., Ton Lemaire, Albert Trouwborst (eds. - Simon Kooijman, Adrian Horridge, Outrigger canoes of Bali and Madura, Indonesia, Bishop museum special bulletin 77, Honolulu: Bishop museum press, 1987. xii + 178 pp., 4 maps, 1 colour photograph, 19 black and white photographs, 71 line drawings. - Jelle Miedema, D.K. Feil, The evolution of highland Papua New Guinea societies, Cambridge: University Press, 1987, xii + 313 pp. - Jelle Miedema, James F. Weiner, Mountain Papuans; Historical and comparitive perspectives from New Guinea fringe highlands societies. Ann Arbor: The University of Michigan Press, 1988, 230 pp. - Jetta Wille, Paulus M.F. van der Grijp, Produktie en denkwijzen in Polynesië; Sociale asymmetrie, ideologie en verandering op de Tonga-eilanden, Proefschrift Nijmegen, 1987.

  6. A community-based study of factors associated with continuing transmission of lymphatic filariasis in Leogane, Haiti.

    Directory of Open Access Journals (Sweden)

    Alexis Boyd

    Full Text Available Seven rounds of mass drug administration (MDA have been administered in Leogane, Haiti, an area hyperendemic for lymphatic filariasis (LF. Sentinel site surveys showed that the prevalence of microfilaremia was reduced to <1% from levels as high as 15.5%, suggesting that transmission had been reduced. A separate 30-cluster survey of 2- to 4-year-old children was conducted to determine if MDA interrupted transmission. Antigen and antifilarial antibody prevalence were 14.3% and 19.7%, respectively. Follow-up surveys were done in 6 villages, including those selected for the cluster survey, to assess risk factors related to continued LF transmission and to pinpoint hotspots of transmission. One hundred houses were mapped in each village using GPS-enabled PDAs, and then 30 houses and 10 alternates were chosen for testing. All individuals in selected houses were asked to participate in a short survey about participation in MDA, history of residence in Leogane and general knowledge of LF. Survey teams returned to the houses at night to collect blood for antigen testing, microfilaremia and Bm14 antibody testing and collected mosquitoes from these communities in parallel. Antigen prevalence was highly variable among the 6 villages, with the highest being 38.2% (Dampus and the lowest being 2.9% (Corail Lemaire; overall antigen prevalence was 18.5%. Initial cluster surveys of 2- to 4-year-old children were not related to community antigen prevalence. Nearest neighbor analysis found evidence of clustering of infection suggesting that LF infection was focal in distribution. Antigen prevalence among individuals who were systematically noncompliant with the MDAs, i.e. they had never participated, was significantly higher than among compliant individuals (p<0.05. A logistic regression model found that of the factors examined for association with infection, only noncompliance was significantly associated with infection. Thus, continuing transmission of LF seems

  7. Patient dosimetry workshop - Scanner in clinical practice: how to optimize one's protocols (acquisition, interpretation, dosimetry)? - Radiation protection in medical environment

    International Nuclear Information System (INIS)

    Valero, M.; Pilleul, F.; Favre, F.; Tack, D.; Etard, C.; Aubert, B.; Roch, P.; Sinno-Tellier, S.; Gevenois, P.A.; Marelle, P.; Noel, A.; Coquel, P.; Museux, E.; Lair, F.; Francois, A.; Lemaire, P.; Delgoffe, C.; Puech, J.L.; Haller Montejo, M.; Rousselle, I.; Noel, A.; Pierrat, N.; Lasalle, S.; Brisse, H.; Guerson, T.; Mertz, L.; Mertz, M.; Wasylczenko, T.; Bietry, J.; Notter, S.; Jahnen, A.; Back, C.; Kohler, S.; Harpes, N.

    2010-01-01

    A selection of eleven brief communications given at the 2010 French days of radiology are compiled here and deal with: 1 - patient's dosimetry in classical radiology (Valero, M.); 2 - Oncology: how to optimize monitoring (dosimetry, new response criteria)? (Pilleul, F.; Favre, F.); 3 - Thorax: how to optimize lecture (MPR - Multi-Planar Reformat, MIP - Maximum Intensity Projection, MinIP - minimum intensity projection) and dosimetry? (Braine-L'Alleud); 4 - Medical exposure of the French population to diagnostic techniques in 2007 (Etard, C.; Aubert, B.; Sinno-Tellier, S.); 5 - Doses delivered to patients in radio-diagnostics: status of a national inquiry in the public sector (Etard, C.; Sinno-Tellier, S.; Aubert, B.); 6 - External help for the dose per section optimization in tomodensitometry (Tack, D.; Jahnen, A.; Back, C.; Kohler, S.; Harpes, N.; Gevenois, P.A.); 7 - Diagnostic reference levels (DRL) in radiology and scanography: status and evolution (Roch, P.; Aubert, B.); 8 - What conclusions can be drawn from the analysis of the DRLs in conventional radiology addressed to the CEPPIM (College for the evaluation of professional practices in medical imaging) (Marelle, P.; Coquel, P.; Museux, E.; Lair, F.; Francois, A.; Lemaire, P.; Delgoffe, C.; Puech, J.L.; Haller Montejo, M.); 9 - DRL analysis in scanography, an optimization tool? (Rousselle, I.; Noel, A.); 10 - Iterative reconstruction in scanography: potential dosimetric benefit and impact on image quality (Pierrat, N.; Lasalle, S.; Guerson, T.; Brisse, H.); 11 - Development of a patient's dose optimisation aided system in medical imaging (Mertz, L.; Mertz, M.; Wasylczenko, T.; Bietry, J.; Notter, S.)

  8. Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection.

    Science.gov (United States)

    Iakoubova, Olga A; Tong, Carmen H; Rowland, Charles M; Luke, May M; Garcia, Veronica E; Catanese, Joseph J; Moomiaie, Remo M; Sotonyi, Peter; Ascady, Gyorgy; Nikas, Demitrios; Dedelias, Panagiotis; Tranquilli, Maryann; Elefteriades, John A

    2014-01-01

    A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD), non-dissecting thoracic aortic aneurysm (TAA), and thoracic aortic aneurysm or dissection (TAAD); the largest effect was observed for the association of rs2118181 with TAD. We investigated whether rs2118181 and rs10519177 were associated with TAD, TAA, and TAAD in the Yale study. The genotypes of rs2118181 and rs10519177 were determined for participants in the Yale study: 637 TAAD cases (140 TAD, 497 TAA) and 275 controls from the United States, Hungary, and Greece. The association of the genotypes with TAD, TAA and TAAD were assessed using logistic regression models adjusted for sex, age, study center and hypertension. In the Yale study, rs2118181 was associated with TAD: compared with non-carriers, carriers of the risk allele had an unadjusted odds ratio for TAD of 1.80 (95% CI 1.15-2.80) and they had odds ratio for TAD of 1.87 (95% CI 1.09-3.20) after adjusting for sex, age, study center and hypertension. We did not find significant differences in aortic size, a potential confounder for TAD, between rs2118181 risk variant carriers and non-carriers: mean aortic size was 5.56 (95% CI: 5.37-5.73) for risk variant carriers (CC+CT) and was 5.48 (95% CI: 5.36-5.61) for noncarriers (TT) (p = 0.56). rs2118181 was not associated with TAA or TAAD. rs10519177 was not associated with TAD, TAA, or TAAD in the Yale study. Thus, the Yale study provided further support for the association of the FBN-1 rs2118181SNP with TAD.

  9. PROGRA2 experiment: new results for dust clouds and regoliths

    Science.gov (United States)

    Renard, J.-B.; Hadamcik, E.; Worms, J.-C.; Levasseur-Regourd, A.-C.; Daugeron, D.

    With the CNES-sponsored PROGRA2 facility, linear polarization of scattered light is performed on various types of dust clouds in microgravity during parabolic flights onboard the CNES- and ESA-sponsored A300 Zéro-G aircraft. Clouds of fluffy aggregates are also studied on the ground when lifted by an air-draught. The effect of the physical properties of the particles, such as the grains size and size distribution, the real part of the refractive index, and the structure is currently being studied. The size distribution of the agglomerates is measured in the field of view from the polarized component images. The large number of phase curves already obtained in the various conditions of measurements, in order to build a database (about 160 curves) allows us to better connect the physical properties with the observed polarization of the dust in the clouds. The aim is to compare these curves with those obtained in the solar system by remote-sensing and in-situ techniques for interplanetary dust, cometary coma, and solid particles in planetary atmospheres (Renard et al., 2003). Measurements on layers of particles (i.e. on the ground) are then compared with remote measurements on asteroidal regoliths and planetary surfaces. New phase curves will be presented and discussed i.e. for quartz samples, crystals, fluffy mixtures of alumina and silica, and a high porosity ``regolith'' analogue made of micron-sized silica spheres. This work will contribute to the choice of the samples to be studied with the IMPACT/ICAPS instrument onboard the ISS. J.-B. Renard, E. Hadamcik, T. Lemaire, J.-C. Worms and A.-C. Levasseur-Regourd (2003). Polarization imaging of dust cloud particles: improvement and applications of the PROGRA2 instrument, ASR 31, 12, 2511-2518.

  10. Information Management Systems for Cultural Heritage and Conservation of World Heritage Sites. The Silk Roads Case Study

    Directory of Open Access Journals (Sweden)

    Ona Vileikis

    2011-12-01

    Full Text Available This paper discusses the application of Information Management Systems (IMS in cultural heritage. IMS offer a set of tools for understanding, inventorying and documenting national, regional and World Heritage properties.  Information Management Systems can assist State Parties, stakeholders and heritage site managers involved in cultural heritage management and conservation by easily mining, sharing and exchanging information from multiple sources based on international standards. Moreover, they aim to record, manage, visualize, analyze and disseminate heritage information. In close collaboration with five Central Asian countries, namely, Turkmenistan, Kazakhstan, Kyrgyzstan, Uzbekistan and Tajikistan; a Belgian consortium headed by the Raymond Lemaire International Centre for Conservation (RLICC, K.U.Leuven is developing the Silk Roads Cultural Heritage Resource Information System (CHRIS. This Web-based Information Management System supports the preparation of the Central Asia Silk Roads serial and transnational nominations on the UNESCO World Heritage list. The project has been set up thanks to the financial support of the Belgian Federal Science Policy Office (BELSPO and in collaboration with UNESCO World Heritage Centre in conjunction with the People’s Republic of China and the Japanese Funds-in-Trust UNESCO project. It provides a holistic approach for the recording, documenta tion, protection and monitoring tasks as part of the management of these potential World Heritage Properties. The Silk Roads CHRIS is easily accessible to the general user, presented in a bilingual English and Russian frame and interoperable, i.e. open for other applications to connect to. In this way, all information for the nomination dossiers is easily verified regarding consistency and quality and ready for managing, periodic reporting and monitoring processes in the respect to the property listed. Fina lly, this study provides a general framework to establish

  11. Clinical effects of an oral supplement rich in antioxidants on skin radiance in women

    Directory of Open Access Journals (Sweden)

    Dumoulin M

    2016-10-01

    Full Text Available Marion Dumoulin, David Gaudout, Benoit Lemaire Activ’Inside, Libourne, France Background: Environmental factors impact the skin aging resulting in decrease of skin radiance. Nutrition and particularly antioxidants could help to fight against skin degradation.Objective: The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx2TM, on the improvement of the skin radiance in women.Methods: The open-label clinical study enrolled 35 women, aged 40–70, with facial dull complexion. Subjects were supplemented orally with a daily dosage of 150 mg of an antioxidant-rich formulation containing superoxide dismutase-rich melon concentrate, grape seed extract rich in monomers of flavanols, vitamin C, and zinc for 8 weeks. Each subject served as her own control. The C.L.B.T.™ test has been used to evaluate facial skin coloring (C, luminosity (L, brightness (B, and transparency (T involved in skin radiance. Facial skin imperfections have been assessed by clinical assessment. Firmness has been evaluated by clinical assessment and cutometer measurement. Finally, an auto-questionnaire has been carried out in order to evaluate the satisfaction of the subjects concerning different parameters involved in skin radiance and the global efficacy of the supplement.Results: Skin “red pink” and “olive” colors were significantly improved after supplementation (P<0.0001. Luminosity was increased by 25.9% (P<0.0001 whereas brightness and transparency were not affected by the supplementation. Facial skin imperfections were significantly reduced after the antioxidant-rich formulation intake (global reduction: –18.0%; P<0.0001. Indeed, dark circles, redness, and spots significantly diminished after oral treatment. Firmness and elasticity have been shown to be improved. Subjects were globally satisfied by the product (82.4% and have found improvements on their facial skin. Furthermore, 64.7% reported to look

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    E.Ch.L. van der Vliet

    1982-01-01

    Full Text Available - Rita Bolland, Alfred Bühler, The patola of Gujarat. Double ikat in India. Krebs AG Basel, 1979. Vol. 1, 360 p. tekst, ill. Vol. 2, afb. in kleur en zwart/wit, krt. tab. noten, verkl. woorden. litl., Eberhard Fischer (eds. - Raymond Buve, Hugo G. Nutini, Ritual kinship. The structure and historical development of the Compadrazgo system in rural Tlaxcala, Vol. I. Princeton University Press, N.J., 1980, XVI plus 494 pp., maps, tables, glossary and index., Betty Bell (eds. - Benno Galjart, G.A. Banck, Jagen met een kat... Schaarse middelen en sociale relaties in de Braziliaanse staat Espirito Santo, CEDLA Incidentele publicaties no. 8, CEDLA, Amsterdam 1977. - R.A.L.H. Gunawardana, J. van Goor, Jan Kompanie as schoolmaster: Dutch education in Ceylon, 1690-1795, Historische Studies, Instituut voor Geschiedenis der Rijksuniversiteit te Utrecht, XXIV, Wolters-Noordhoff Groningen, 1978, 205 pp., 3 maps. - Ria Kloppenborg, R.A.L.H. Gunawardana, Robe and plough. Monasticism and economic interest in early medieval Sri Lanka. Association for Asian Studies, Monographs and Papers No. XXXV, University of Arixona Press, Tucson, Arizona, 1979; 377 pages, including bibliography and index. - Els Postel-Coster, Jan van Bremen, Romantropologie - Essays over antropologie en literatuur, Antropologisch-Sociologisch Centrum Universiteit van Amsterdam, 1979., Sjaak van der Geest, Jojada Verrips (eds. - Arie de Ruijter, T. Lemaire, Over de waarde van kulturen. Een inleiding in de kultuurfilosofie. Ambo, Baarn 1976, herdruk 1980. 509 blz. - P. van de Velde, W. Arens, The man-eating myth. Oxford University Press, New York, 1979. XIV + 206 pp., 12 illustrations. - E.Ch.L. van der Vliet, Klaus E. Müller, Geschichte der antiken ethnographie und ethnologischen theoriebildung von den anfängen bis auf die byzantinischen historiographen, Teil II (Studien zur Kulturkunde 52, Wiesbaden: Franza Steiner Verlag, 1980. 563 pp. 11 figs. - J.J. de Wolf, P.T.W. Baxter, Age

  13. Review on hydroxylamine, a precursor to amino-acids

    Science.gov (United States)

    Lemaire, Jean Louis

    2015-08-01

    Does life on earth come from interstellar space (IS)?It has been recently demonstrated that part of the terrestrial water is of IS origin [Cleeves et al. Science 2014]. This raises the question whether materials like amino-acids or their pre-biotic molecular precursors could have been formed and brought to earth in the same way than water. Another question is whether these molecules were formed in the gas phase or through reactions on the surface/volume of ice-covered grains. This may then have occurred in the vicinity of proto-stellar cores or deep into a pristine dense molecular clouds at very low temperatures.As far as bio-related molecules are concerned, chemistry with nitrogen-bearing molecules (like NH3 and NO) is involved. I review recent experimental work showing that hydroxylamine (NH2OH) could be formed either by surface or by volume reactions in conditions close to those prevailing in dense media. They use either electron-UV irradiation of water-ammonia ices [Zheng & Kaiser JCPA 2010] or successive hydrogenation of solid nitric oxide[Congiu, Fedoseev & al. ApJL.2012] or the simple oxidation of ammonia [He, Vidali, Lemaire & Garrod, ApJ, 2015] or the reaction of ammonia with hydroxyl radicals in a rare gas matrix [Zins & Krim, 2014, 69th ISMS]. A step further, the synthesis of the simplest amino-acids, glycine (NH2CH2COOH) and L- or D-alanine (NH2CH3CHCOOH) has already been obtained via reactions in the gas phase involving NH2OH+ [Blagojevic & al. MNRAS 2003].In addition to several earlier models demonstrating that the formation of all these molecules is possible in the gas phase, a new recent three-phase gas-grain chemical kinetics model of hot cores [Garrod ApJ 2013] shows that the results of ammonia oxidation we obtain are plausible by surface/volume reactions.Although none of the aforementioned molecules (except glycine in a sample of cometary origin) has been yet detected in the IS, they all are considered by many observers and modelers as likely

  14. Innovative synthesis of meso-structured YSZ using V2O5 complex fluids as a template

    International Nuclear Information System (INIS)

    Guiot, Camille; Grandjean, Stephane; Batail, Patrick

    2008-01-01

    .-C.P.; Camerel, F.; Lemaire, B. J.; Desvaux,H.; Davidson, P.; Batail, P.; Nature, 413, 504 (2001). (authors)

  15. Mineralogical, IR-spectral and geochemical monitoring of hydrothermal alteration in a deformed and metamorphosed Jurassic VMS deposit at Arroyo Rojo, Tierra del Fuego, Argentina

    Science.gov (United States)

    Biel, C.; Subías, I.; Acevedo, R. D.; Yusta, I.; Velasco, F.

    2012-04-01

    The Arroyo Rojo Zn-Pb-Cu volcanogenic massive sulfide deposit is the main deposit of the Fin del Mundo District in the Fuegian Andes, Argentina. This deposit is hosted by a Middle Jurassic volcanic and volcanoclastic sequence forming the Lemaire Formation. The latter consists, from the base up, of the following: rhyolitic and dacitic porphyritic rocks, ignimbrite, tuff, and flow. It is underlain by a pre-Jurassic basement and overlain by the hyaloclastic andesites of the Yahgán Formation. The Arroyo Rojo consists of stacked lenticular lenses that are associated with disseminated mineralization in both the footwall and the hanging wall. The internal structure of the ore lenses is marked by the occurrence of massive, semi-massive and banded facies, along with stringer and brecciated zones and minor ore disseminations. The mineral assemblage comprises mainly pyrite and sphalerite, with minor amounts of galena and chalcopyrite and rare pyrrhotite, arsenopyrite, tetrahedrite and bournonite. The ores and the volcanic host rocks have metamorphosed to greenschist facies and were overprinted by a penetrative tectonic foliation, which led to the development of mylonitic, and cataclastic textures, recrystallization and remobilization. Primary depositional characteristics and regional and hydrothermal alteration patterns were preserved despite deformation and metamorphism. Therefore, primary banding was preserved between facies boundaries. In addition, some remnants of magmatic origin are recognizable in preserved phenocrysts and volcaniclastic phenoclasts. Most of the volcanic and volcaniclastic rocks of the host sequence show a rhyolitic to rhyo-dacitic composition. Regional seafloor alteration, characterized by the presence of clinozoisite, Fe-chlorite and titanite, along with quartz and albite, is partially obliterated by hydrothermal alteration. The hydrothermal alteration is stratabound with the following assemblages, which developed from the base to top: (1) Quartz

  16. High hydrostatic pressure influences the in vitro response to xenobiotics in Dicentrarchus labrax liver

    Energy Technology Data Exchange (ETDEWEB)

    Lemaire, Benjamin; Mignolet, Eric; Debier, Cathy [Institut des Sciences de la Vie, Université Catholique de Louvain, Croix du Sud 2, B-1348 Louvain-la-Neuve (Belgium); Calderon, Pedro Buc [Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Mounier 73, B-1200 Woluwé-Saint-Lambert (Belgium); Thomé, Jean Pierre [Laboratoire d’Ecologie Animale et Ecotoxicologie, Université de Liège, Allée du 6 août 15, B-4000 Liège (Belgium); Rees, Jean François, E-mail: jf.rees@uclouvain.be [Institut des Sciences de la Vie, Université Catholique de Louvain, Croix du Sud 2, B-1348 Louvain-la-Neuve (Belgium)

    2016-04-15

    Highlights: • The methodology of precision-cut liver slices was applied to the European seabass. • Liver slices remained viable and functional in short-term co-exposure studies. • CYP1A induction was blocked in slices exposed to an AhR agonist at high pressure. • HSP70 induction was lower in slices exposed to an AhR agonist at high pressure. • Oxidative stress responses to tBHP were less pronounced at high pressure. - Abstract: Hydrostatic pressure (HP) increases by about 1 atmosphere (0.1 MPa) for each ten-meter depth increase in the water column. This thermodynamical parameter could well influence the response to and effects of xenobiotics in the deep-sea biota, but this possibility remains largely overlooked. To grasp the extent of HP adaptation in deep-sea fish, comparative studies with living cells of surface species exposed to chemicals at high HP are required. We initially conducted experiments with precision-cut liver slices of a deep-sea fish (Coryphaenoides rupestris), co-exposed for 15 h to the aryl hydrocarbon receptor (AhR) agonist 3-methylcholanthrene at HP levels representative of the surface (0.1 MPa) and deep-sea (5–15 MPa; i.e., 500–1500 m depth) environments. The transcript levels of a suite of stress-responsive genes, such as the AhR battery CYP1A, were subsequently measured (Lemaire et al., 2012; Environ. Sci. Technol. 46, 10310–10316). Strikingly, the AhR agonist-mediated increase of CYP1A mRNA content was pressure-dependently reduced in C. rupestris. Here, the same co-exposure scenario was applied for 6 or 15 h to liver slices of a surface fish, Dicentrarchus labrax, a coastal species presumably not adapted to high HP. Precision-cut liver slices of D. labrax were also used in 1 h co-exposure studies with the pro-oxidant tert-butylhydroperoxide (tBHP) as to investigate the pressure-dependence of the oxidative stress response (i.e., reactive oxygen production, glutathione and lipid peroxidation status). Liver cells remained

  17. A comparison study between observations and simulation results of Barghouthi model for O+ and H+ outflows in the polar wind

    Directory of Open Access Journals (Sweden)

    I. A. Barghouthi

    2011-11-01

    + ions at altitudes below ~7 RE, while it is important for altitudes above 7 RE. For O+ wave particle interaction is very significant at all altitudes. (3 For certain λ⊥ and at points, altitudes, where the ion gyroradius is equal to or less than λ⊥, the effect of wave-particle interactions is independent of the velocity and it depends only on the altitude part of the velocity diffusion coefficient; however, the effect of wave-particle interactions reduce above that point, called saturation point, and the heating process turns to be self-limiting heating. (4 The most interesting result is the appearance of O+ conics and toroids at low altitudes and continue to appear at high altitudes; however, they appear at very high altitudes for H+ ions. We compare quantitatively and qualitatively between the simulation results and the corresponding observations. As a result of many comparisons, we find that the best agreement occurs when λ⊥ equals to 8 km. The quantitative comparisons show that many characteristics of the observations are very close to the simulation results, and the qualitative comparisons between the simulation results for ion outflows and the observations produce very similar behaviors. To our knowledge, most of the comparisons between observations (ion velocity distribution, density, drift velocity, parallel and perpendicular temperatures, anisotropy, etc. and simulations obtained from different models produce few agreements and fail to explain many observations (see Yau et al., 2007; Lemaire et al., 2007; Tam et al., 2007; Su et al., 1998; Engwall et al., 2009. This paper presents many close agreements between observations and simulations obtained by Barghouthi model, for O+ and H+ ions at different altitudes i.e. from 1.7 RE to 13.7 RE.

  18. High hydrostatic pressure influences the in vitro response to xenobiotics in Dicentrarchus labrax liver

    International Nuclear Information System (INIS)

    Lemaire, Benjamin; Mignolet, Eric; Debier, Cathy; Calderon, Pedro Buc; Thomé, Jean Pierre; Rees, Jean François

    2016-01-01

    Highlights: • The methodology of precision-cut liver slices was applied to the European seabass. • Liver slices remained viable and functional in short-term co-exposure studies. • CYP1A induction was blocked in slices exposed to an AhR agonist at high pressure. • HSP70 induction was lower in slices exposed to an AhR agonist at high pressure. • Oxidative stress responses to tBHP were less pronounced at high pressure. - Abstract: Hydrostatic pressure (HP) increases by about 1 atmosphere (0.1 MPa) for each ten-meter depth increase in the water column. This thermodynamical parameter could well influence the response to and effects of xenobiotics in the deep-sea biota, but this possibility remains largely overlooked. To grasp the extent of HP adaptation in deep-sea fish, comparative studies with living cells of surface species exposed to chemicals at high HP are required. We initially conducted experiments with precision-cut liver slices of a deep-sea fish (Coryphaenoides rupestris), co-exposed for 15 h to the aryl hydrocarbon receptor (AhR) agonist 3-methylcholanthrene at HP levels representative of the surface (0.1 MPa) and deep-sea (5–15 MPa; i.e., 500–1500 m depth) environments. The transcript levels of a suite of stress-responsive genes, such as the AhR battery CYP1A, were subsequently measured (Lemaire et al., 2012; Environ. Sci. Technol. 46, 10310–10316). Strikingly, the AhR agonist-mediated increase of CYP1A mRNA content was pressure-dependently reduced in C. rupestris. Here, the same co-exposure scenario was applied for 6 or 15 h to liver slices of a surface fish, Dicentrarchus labrax, a coastal species presumably not adapted to high HP. Precision-cut liver slices of D. labrax were also used in 1 h co-exposure studies with the pro-oxidant tert-butylhydroperoxide (tBHP) as to investigate the pressure-dependence of the oxidative stress response (i.e., reactive oxygen production, glutathione and lipid peroxidation status). Liver cells remained

  19. High hydrostatic pressure influences the in vitro response to xenobiotics in Dicentrarchus labrax liver.

    Science.gov (United States)

    Lemaire, Benjamin; Mignolet, Eric; Debier, Cathy; Calderon, Pedro Buc; Thomé, Jean Pierre; Rees, Jean François

    2016-04-01

    Hydrostatic pressure (HP) increases by about 1 atmosphere (0.1MPa) for each ten-meter depth increase in the water column. This thermodynamical parameter could well influence the response to and effects of xenobiotics in the deep-sea biota, but this possibility remains largely overlooked. To grasp the extent of HP adaptation in deep-sea fish, comparative studies with living cells of surface species exposed to chemicals at high HP are required. We initially conducted experiments with precision-cut liver slices of a deep-sea fish (Coryphaenoides rupestris), co-exposed for 15h to the aryl hydrocarbon receptor (AhR) agonist 3-methylcholanthrene at HP levels representative of the surface (0.1MPa) and deep-sea (5-15MPa; i.e., 500-1500m depth) environments. The transcript levels of a suite of stress-responsive genes, such as the AhR battery CYP1A, were subsequently measured (Lemaire et al., 2012; Environ. Sci. Technol. 46, 10310-10316). Strikingly, the AhR agonist-mediated increase of CYP1A mRNA content was pressure-dependently reduced in C. rupestris. Here, the same co-exposure scenario was applied for 6 or 15h to liver slices of a surface fish, Dicentrarchus labrax, a coastal species presumably not adapted to high HP. Precision-cut liver slices of D. labrax were also used in 1h co-exposure studies with the pro-oxidant tert-butylhydroperoxide (tBHP) as to investigate the pressure-dependence of the oxidative stress response (i.e., reactive oxygen production, glutathione and lipid peroxidation status). Liver cells remained viable in all experiments (adenosine triphosphate content). High HP precluded the AhR agonist-mediated increase of CYP1A mRNA expression in D. labrax, as well as that of glutathione peroxidase, and significantly reduced that of heat shock protein 70. High HP (1h) also tended per se to increase the level of oxidative stress in liver cells of the surface fish. Trends to an increased resistance to tBHP were also noted. Whether the latter observation truly

  20. Autonomy and heteronomy. Integration and sustainability of essential flows in the built environment; Autonomie en heteronomie. Integratie en verduurzaming van essentiele stromen in de gebouwde omgeving

    Energy Technology Data Exchange (ETDEWEB)

    Van Timmeren, A.

    2006-06-23

    specifieke kenmerken van de traditionele paradigmas, lijkt bij een grote groep van de relevante actoren nog te ontbreken. Dit onderzoek benadrukt het belang voor volhoudbaarheid van een wederkerige relatie tussen centrale en decentrale systemen, en de integratie (interconnectie) van oplossingen voor de energie, afval en afvalwatervoorziening. Gesteld kan worden dat differentiatie en flexibiliteit op het gebied van ruimtelijke ordening voorwaardelijk zijn om te kunnen inspelen op de onzekerheden op de lange termijn. Voorkomen moet worden dat het proces van verstedelijking en de uitleg van infrastructurele netwerken, gebaseerd op het op afstand transporteren en oplossen van de essenti stromen, zich los van elkaar ontwikkelen. Een nauwkeurige, integrale (Eu)regionale planning gebaseerd op een combinatie van conventionele (centrale) systemen en toegevoegde decentrale systemen vermindert de risicos van mogelijke impasse als gevolg van onvolhoudbaarheid van de bestaande netwerken en systemen, met alle bijkomende gezondheidsrisicos. De cultuurfilosoof Ton Lemaire stelde hieromtrent waar het op aan komt, is de juiste verhouding te vinden tussen het globale en het lokale. Het lokale zou door de globalisering niet teniet moeten worden gedaan maar opnieuw een plaats moeten krijgen. Een uitwerking van volhoudbaarheid, voorzieningszekerheid en onafhankelijkheid lijkt zowel in geval van verdere ontwikkeling op grond van het toekomstpad van schaalvergroting (economies of scale) als van decentralisatie (scale economy) noodzakelijk, zo niet essentieel. Het komt neer op het beter combineren van voordelen van autonomie en heteronomie.

  1. Dismantling of nuclear facilities and related problems - Conference proceedings

    International Nuclear Information System (INIS)

    Tournebize, Frederic; Bordet, Didier; Charlety, Philippe; Gore, Thierry; Estrade, Jerome; Lemaire, Hermine; Ginet, Annick; Fabrier, Lionel; Evrard, Lydie; Furois, Timothee; Butez, Marc; Dutzer, Michel; Faure, Vincent; Billarand, Yann; Menuet, Lise; Lahaye, Thierry; Pin, Alain; Mougnard, Philippe; Charavy, Sylvain; Poncet, Philippe; Moggia, Fabrice; Dochy, Arnaud; Benjamin, Patrick; Poncet, Pierre-Emmanuel; Beneteau, Yannick; Richard, Jean-Baptiste; Pellenz, Gilles; Ollivier Dehaye, Catherine; Gerard, Stephane; Denissen, Luc; Davain, Henri; Duveau, Florent; Guyot, Jean-Luc; Ardellier, Luc

    2012-11-01

    facilitating the definitive shutdown of the Jules Horowitz reactor (J. Estrade); 17 - Integration of dismantling at the design stage of the French EPR reactor (Y. Beneteau, J.P. Richard); 18 - Use of the Gampix gamma camera at dismantling sites (H. Lemaire); 19 - Stakes for the wastes intended to be disposed off in waste centres in operation (F. Dutzer); 20 - Cleansing of non-nuclear contaminated sites (V. Faure); 21 - Rehabilitation of dismantling sites - management plan for the old effluents channel of the Brennilis effluents processing plant (G. Pellenz, C. Ollivier-Dehaye); 22 - Problem of confinement keeping during deconstruction (A. Ginet, L. Fabrier); 23 - Project of wells cleansing at the irradiated materials workshop (AMI) of Chinon NPP (F. Duveau); 24 - Nuclear decontamination using a laser (F. Moggia); 25 - TIVA, adaptable and ventilated intervention dress (A. Dochy, P. Benjamin); 26 - Dismantling project - optimisation thanks to virtual reality-based software solutions (L. Ardellier, A. Pin)

  2. Seeing Is Believing. Or Is It?

    Science.gov (United States)

    Moore, John W.

    1999-08-01

    Occasionally I get time to read something other than a scientific journal, book, or manuscript. On one such foray I discovered Kenneth Brower's "Photography in the Age of Falsification", which appeared in The Atlantic Monthly in May 1998. Brower described how an editor, who might never have experienced the wildness of nature, could conceive a photograph and assign a photographer to create it. Whether the scene depicted was actually possible often seemed relatively unimportant. The main thing was whether the image would interest viewers. Brower argued that today's vast array of software for manipulating digital versions of photographic images enables what he calls "photofakery" on an unprecedented scale. He described how editors at National Geographic decided to pull an ad that depicted a polar bear in Antarctica (where there are no bears); the ad had been created by digitally superimposing a photograph of a bear in a Cincinnati zoo and a photograph of the Lemaire Channel in Antarctica. According to Brower, "Too few photographers, I think, appreciate how directly the new technology aims at the heart of the credibility that distinguishes this art form from others." Credibility is also one of the hallmarks of science. Science progresses as a result of consensus on what results can be expected from carefully designed and carefully executed experiments and observations. As teachers of chemistry, we have a duty not to fall into the same kinds of traps that have made some photographers uneasy about their profession. And we need to help our students learn to avoid these traps. But it is not that easy, because we also need to capture students' attention and try to make our subject interesting by telling stories or showing phenomena or models that appeal to the imagination. As in the case of photography, defining where imagination begins to usurp reality is difficult. It is therefore a very important issue to wrestle with. Part of Brower's argument against manipulation of