WorldWideScience

Sample records for astatine 200

  1. Bibliography of astatine chemistry and biomedical applications

    International Nuclear Information System (INIS)

    An overall bibliography is presented on astatine chemistry and on the biomedical applications of its 211At isotope. The references were grouped in the following chapters: General reviews; Discovery, Natural Occurence; Nuclear Data; Preparation, Handling, Radiation Risk; Physico-chemical Properties; Astatine Compounds and Chemical Reactions; Biological Effects and Applications. Entries are sorted alphabetically by authors name in each chapter, and cross-references to other chapters are provided if appropriate. (R.P.)

  2. Astatine-211: production and availability.

    Science.gov (United States)

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production. PMID:22201707

  3. Adsorption interaction of astatine species with quartz and gold surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Serov, A. [Paul Scherrer Institute, Villigen (Switzerland). Lab. for Radiochemistry and Environmental Chemistry; Bern Univ. (Switzerland). Dept. for Chemistry and Biochemistry; Aksenov, N.; Bozhikov, G. [Joint Institute for Nuclear Research, Dubna (RU). Flerov Lab. of Nuclear Reactions] (and others)

    2011-07-01

    The adsorption interaction of various astatine species with quartz and gold surfaces was investigated by gas chromatography methods. Due to variations of the redox potential of the carrier gas elemental astatine, astatine oxide and hypo-astatic acid have been produced. The identification of the astatine compounds is based on the analogy assumption to the gas phase chemistry of the closest homologues in group 17 of the periodic table, iodine and bromine. The deposition temperatures as well as enthalpies of adsorption have been determined for the astatine species. The enhancement of the metallic character within group 17 towards higher Z is clearly confirmed. Macroscopic properties (sublimation enthalpy) of previously unstudied AtO{sub 2} and HAtO were estimated. The determined data for elemental astatine were compared to available literature data. Based on the obtained experimental results possible designs of experiments for studying of chemical properties of the recently discovered element 117 can be suggested. (orig.)

  4. Recent advances in the organic chemistry of astatine

    International Nuclear Information System (INIS)

    Investigation on the chemical behaviour of astatine in the last decade are surveyed. The survey covers the physical and chemical properties of astatine, synthesis and identification of organic astatine compounds, their physicochemical properties. A special chapter is devoted to biomedical applications, including inorganic 211At species, 211At-labelled proteins and drugs. An extensive bibliography of the related literature is given. (N.T.) 129 refs.; 12 figs.; 14 tabs

  5. Discovery of the astatine, radon, francium, and radium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, thirty-nine astatine, thirty-nine radon, thirty-five francium, and thirty-four radium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  6. Extraction of astatine isotopes for development of radiopharmaceuticals using a 211Rn-211At generator

    International Nuclear Information System (INIS)

    In order to utilize a 211At isotope, a promising α-emitter for radionuclide therapy, the chemical properties of astatine isotopes are studied. We have examined wet chemistry methods through the distribution ratios of astatine in liquid-liquid extraction. The astatine isotopes have been found to be well extracted into DIPE and MIBK. We observed that the distribution ratio of astatine isotopes increases with concentrations of HCl greater than 3 M, while it decreases with the HCl concentration less than 2 M. The results will be useful for development of the 211Rn-211At generator. (author)

  7. Astatine-211-Labeled Targeted Radiotherapeutics: An Update

    International Nuclear Information System (INIS)

    The heavy halogen 211At was first proposed for use in α-particle targeted radiotherapy more than 30 years ago and continues to be one of the most promising radionuclides for this purpose. Although its 7.2-h half life is not ideal for intravenously administered whole antibodies, it is compatible with the pharmacokinetics of antibody fragments, peptides, aptamers and organic molecules. Its diverse chemistry allows its incorporation into a wide array of targeting vehicles, relying on its chemical similarity to iodine to provide a useful point of departure. On the other hand, the relatively low carbon-astatine bond strength is challenging. In common with the other α-emitters being discussed at this symposium, lack of reliable availability is one of the biggest hurdles in the use of 211At for targeted radiotherapy. However, in the case of 211At, it is not a question of production cost or availability of target material, because 211At can be produced in reasonable yield from natural bismuth targets. Rather, the difficulty is the lack of cyclotrons equipped with the medium energy α-particle beams required for its production. If the infrastructure for producing 211At is to be improved to the stage where 211At-labeled radiopharmaceuticals can have a meaningful impact, several developments must occur. First, the ability to produce clinically relevant levels of 211At that can be shipped to remote locations in chemically tractable form must be demonstrated. Approaches under consideration include compensating for radiolysis-mediated effects and the consideration of alternative chemistries. Second, strategies for compensating for heterogeneities in dose deposition must be developed, hopefully in a way that is compatible with approval for human use. And third, it is essential that more clinical trials be performed with 211At-labeled therapeutics, particularly in settings of minimum residual disease where the radiobiological advantages of α-particles can be best exploited. Our

  8. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    CERN Document Server

    Rothe, S; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yu; Köster, U; Lane, J; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of smallest quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.317510(8) eV. New ab initio calculations were performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of super-heavy element 117, the heaviest homologue of astatine.

  9. Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates.

    Science.gov (United States)

    Aneheim, Emma; Gustafsson, Anna; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Svedhem, Sofia; Lindegren, Sture

    2016-03-16

    Effective treatment of metastasis is a great challenge in the treatment of different types of cancers. Targeted alpha therapy utilizes the short tissue range (50-100 μm) of α particles, making the method suitable for treatment of disseminated occult cancers in the form of microtumors or even single cancer cells. A promising radioactive nuclide for this type of therapy is astatine-211. Astatine-211 attached to tumor-specific antibodies as carrier molecules is a system currently under investigation for use in targeted alpha therapy. In the common radiolabeling procedure, astatine is coupled to the antibody arbitrarily on lysine residues. By instead coupling astatine to disulfide bridges in the antibody structure, the immunoreactivity of the antibody conjugates could possibly be increased. Here, the disulfide-based conjugation was performed using a new coupling reagent, maleimidoethyl 3-(trimethylstannyl)benzamide (MSB), and evaluated for chemical stability in vitro. The immunoconjugates were subsequently astatinated, resulting in both high radiochemical yield and high specific activity. The MSB-conjugate was shown to be stable with a long shelf life prior to the astatination. In a comparison of the in vivo distribution of the new immunoconjugate with other tin-based immunoconjugates in tumor-bearing mice, the MSB conjugation method was found to be a viable option for successful astatine labeling of different monoclonal antibodies. PMID:26791409

  10. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    OpenAIRE

    Rothe, S.; A. N. Andreyev; Antalic, S; Borschevsky, A.; Capponi, L.; Cocolios, T.E.; Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the io...

  11. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    DEFF Research Database (Denmark)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom;

    2015-01-01

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical...... and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting...... vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method...

  12. Study of Astatine (III) reactions with O, S and N ligands in solution

    International Nuclear Information System (INIS)

    Full text of publication follows. Astatine (At, Z=85: [Xe]4f145d106s26p5) belongs to the halogen group and is located below iodine in the periodic table. One of its isotopes (211At) appears promising as a therapeutic agent in nuclear medicine (Ref.1) owing to the energy of the alpha particles emitted during the disintegration of its nucleus and its short physical half-life (7.2 h). Since there are no stable isotopes of astatine, the chemistry of this element remains poorly understood. Generally, At is supposed to behave as a halogen (Ref.2) but it has been shown recently in our group that astatine presents a metallic behaviour in aqueous solution: it notably exists as At+ and AtO+ species under the oxidation states +I and +III (Ref.3). At the present time, the number of studies dealing with the complexation properties of the cationic forms of astatine remains limited (Ref.4), owing to its low availability. In this work, we have investigated the reactions of AtO+ species with different hetero-atomic (N, S, O) model ligands. A combined approach based on experimental and theoretical studies has been used (Ref.5). On account of the difficulties of experimental investigations of astatine species, the reactivity of AtO+ was explored using a competition method founded on astatine distributions between two distinct phases. Furthermore, for each AtO+/ ligand complex, the nature of the species formed and the associated thermodynamic constants were determined by computational modeling (DFT calculations). In this framework, an original computational methodology was developed to take into account the specificities of astatine, notably the associated relativistic effects. The computed equilibrium constants have been confronted with the experimental results. This comparison demonstrates an outstanding coherence between experience and theory. Furthermore, the analysis of the results shows a key role of solvent effects on astatine chemistry. Lastly, a specific reactivity for the

  13. Some aspects of the organic, biological and inorganic chemistry of astatine

    International Nuclear Information System (INIS)

    Astatine has no stable isotopes and the radioactive isotopes with half-lives sufficiently long for chemical experiments (209At, 210At, 211At) must be produced artificially with a cyclotron or with a high energy accelerator by spallation of Th. This thesis deals with the synthesis and chemistry of At-compounds and the determination of some of their properties. (C.F.)

  14. Astatine-211 Pathway from Radiochemistry to Clinical Investigation

    International Nuclear Information System (INIS)

    Particularly in clinical settings where tumour burden is low and cancers are located in close proximity to essential normal tissue structures, α-particle emitting radionuclides can offer significant advantages for targeted radionuclide therapy. One of the first alpha emitters to be evaluated for this purpose is the 7.2-h half-life radiohalogen Astatine-211 (211At). From a commercialization-potential perspective 211At, is less appealing than the longer half-life alpha particle emitters Radium-223, Actinium-225 and Thorium-227, which have become the focus of many laboratories. However, if methods for providing a better supply of 211At could be developed, this alpha emitter would be the radionuclide of choice for many potential therapeutic applications. With regard to the production of 211At, this can be readily be accomplished by bombarding natural bismuth targets with 28−29.5 MeV alpha particles via the 209Bi(α,2n)211At reaction. The goal is to utilize an alpha particle beam energy that provides the required balance for maximizing 211At production while minimizing creation of 210At, which is problematic because of its 138.4-day half life alpha-particle emitting daughter, 210Po. For most intended clinical applications, alpha particle beam energy of about 29 MeV offers the best compromise between maximizing yield and providing 211At with sufficient radionuclidic purity for clinical use. Clinically relevant levels of 211At have been produced at several institutions using both internal and external cyclotron targets

  15. An attempt to explore the production routes of Astatine radionuclides: Theoretical approach

    OpenAIRE

    Maiti, Moumita; Lahiri, Susanta

    2008-01-01

    In order to fulfil the recent thrust of Astatine radionuclides in the field of nuclear medicine various production routes have been explored in the present work. The possible production routes of $^{209-211}$At comprise both light and heavy ion induced reactions at the bombarding energy range starting from threshold to maximum 100 MeV energy. For this purpose, we have used the nuclear reaction model codes TALYS, ALICE91 and PACE-II. Excitation functions of those radionuclides, produced throug...

  16. Determination of the electron affinity of astatine and polonium by laser photodetachment

    CERN Multimedia

    We propose to conduct the first electron anity (EA) measurements of the two elements astatine (At) and polonium (Po). Collinear photodetachment spectroscopy will allow us to measure these quantities with an uncertainty limited only by the spectral linewidth of the laser. We plan to use negative ion beams of the two radioactive elements At and Po, which are only accessible on-line and at ISOLDE. The feasibility of our proposed method and the functionality of the experimental setup have been demonstrated at ISOLDE in o-line tests by the clear observation of the photodetachment threshold for stable iodine. This proposal is based on our Letter of Intent I-148 [1].

  17. Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

    Science.gov (United States)

    Guérard, François; Lee, Yong-Sok; Baidoo, Kwamena; Gestin, Jean-François; Brechbiel, Martin W

    2016-08-22

    Aryliodonium salts have become precursors of choice for the synthesis of (18) F-labeled tracers for nuclear imaging. However, little is known on the reactivity of these compounds with heavy halides, that is, radioiodide and astatide, at the radiotracer scale. In the first comparative study of radiohalogenation of aryliodonium salts with (125) I(-) and (211) At(-) , initial experiments on a model compound highlight the higher reactivity of astatide compared to iodide, which could not be anticipated from the trends previously observed within the halogen series. Kinetic studies indicate a significant difference in activation energy (Ea =23.5 and 17.1 kcal mol(-1) with (125) I(-) and (211) At(-) , respectively). Quantum chemical calculations suggest that astatination occurs via the monomeric form of an iodonium complex whereas iodination occurs via a heterodimeric iodonium intermediate. The good to excellent regioselectivity of halogenation and high yields achieved with diversely substituted aryliodonium salts indicate that this class of compounds is a promising alternative to the stannane chemistry currently used for heavy radiohalogen labeling of tracers in nuclear medicine. PMID:27305065

  18. Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

    CERN Document Server

    Andreyev, Andrei

    2013-01-01

    Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

  19. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    Energy Technology Data Exchange (ETDEWEB)

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  20. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, Sebastian

    2012-09-24

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  1. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    International Nuclear Information System (INIS)

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  2. 200 aastat kunstiharidust Eestis

    Index Scriptorium Estoniae

    2002-01-01

    5. XII tähistati TÜ kunstimuuseumis 200 aasta möödumist professionaalse kunstihariduse algusest Eestis. Avati kunstinäitus, esitleti kataloogi "200 aastat kunstiharidust Eestis - Tartu Ülikooli joonistuskool 1803-1893"

  3. Radiobiological Effects of Alpha-Particles from Astatine-211: From DNA Damage to Cell Death

    Energy Technology Data Exchange (ETDEWEB)

    Claesson, Kristina

    2011-05-15

    In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an alpha-particle emitting radionuclide, promising for targeted radioimmunotherapy of isolated tumor cells and microscopic clusters. To improve development of safe radiotherapy using 211At it is important to increase our knowledge of the radiobiological effects in cells. During radiotherapy, both tumors and adjacent normal tissue will be irradiated and therefore, it is of importance to understand differences in the radio response between proliferating and resting cells. The aim of this thesis was to investigate effects in fibroblasts with different proliferation status after irradiation with alpha-particles from 211At or X-rays, from inflicted DNA damage, to cellular responses and biological consequences. Throughout this work, irradiation was performed with alpha-particles from 211A or X-rays. The induction and repair of double-strand breaks (DSBs) in human normal fibroblasts were investigated using pulsed-field gel electrophoresis and fragment analysis. The relative biological effectiveness (RBE) of 211At for DSB induction varied between 1.4 and 3.1. A small increase of DSBs was observed in cycling cells compared to stationary cells. The repair kinetics was slower after 211At and more residual damage was found after 24 h. Comparison between cells with different proliferation status showed that the repair was inefficient in cycling cells with more residual damage, regardless of radiation quality. Activation of cell cycle arrests was investigated using immunofluorescent labeling of the checkpoint kinase Chk2 and by measuring cell cycle distributions with flow cytometry analysis. After alpha-particle irradiation, the average number of Chk2-foci was larger and the cells had a more affected cell cycle progression for several weeks compared with X-irradiated cells, indicating a more powerful arrest after 211At

  4. FIN 200 UOP Course Tutorial / fin200dotcom

    OpenAIRE

    anil14

    2015-01-01

    FIN 200 Entire Course For more course tutorials visit   www.fin200.com   FIN 200 Week 1 CheckPoint Financial Management Goals FIN 200 Week 1 Assignment Cash Flow Preparation FIN 200 Week 2 Checkpoint Financial Ratios FIN 200 Week 2 DQ 1 & DQ 2 FIN 200 Week 3 CheckPoint Financial Forecasting FIN 200 Week 3 Assignment Pro Forma Statements FIN 200 Week 4 Checkpoint Break Even Analysis FIN 200 Week 4 DQ 1 & DQ 2 FIN 200 Week 5 CheckPo...

  5. FIN 200 Uop Material-fin200dotcom

    OpenAIRE

    Sandywilliam6

    2015-01-01

    FIN 200 Entire Course For more course tutorials visit   www.fin200.com   FIN 200 Week 1 CheckPoint Financial Management Goals FIN 200 Week 1 Assignment Cash Flow Preparation FIN 200 Week 2 Checkpoint Financial Ratios FIN 200 Week 2 DQ 1 & DQ 2 FIN 200 Week 3 CheckPoint Financial Forecasting FIN 200 Week 3 Assignment Pro Forma Statements FIN 200 Week 4 Checkpoint Break Even Analysis FIN 200 Week 4 DQ 1 & DQ 2 FIN 200 Week 5 CheckPo...

  6. AED 200 Courses Tutorial / indigohelp

    OpenAIRE

    nesa

    2015-01-01

    AED 200 Week 1 DQ1 and DQ2 AED 200 Week 1 CheckPoint Teacher Certification Licensure AED 200 Week 2 CheckPoint Students Social Challenges AED 200 Week 2 CheckPoint Social Justice AED 200 Week 2 Assignment Multicultural Education Scenario AED 200 Week 3 DQ 1 and DQ 2 AED 200 Week 3 CheckPoint School Funding Issues AED 200 Week 4 CheckPoint Religion in Schools AED 200 Week 4 CheckPoint Debate Project Outline AED 200 Week 4 Assignment Students Rights and Teach...

  7. Status of EXO-200

    Energy Technology Data Exchange (ETDEWEB)

    Ackerman, Nicole; /SLAC

    2011-12-06

    EXO-200 is the first phase of the Enriched Xenon Observatory (EXO) experiment, which searches for neutrinoless double beta decay in {sup 136}Xe to measure the mass and probe the Majorana nature of the neutrino. EXO-200 consists of 200 kg of liquid Xe enriched to 80% in {sup 136}Xe in an ultra-low background TPC. Energy resolution is enhanced through the simultaneous collection of scintillation light using Large Area Avalanche Photodiodes (LAAPD's) and ionization charge. It is being installed at the WIPP site in New Mexico, which provides a 2000 meter water-equivalent overburden. EXO-200 will begin taking data in 2009, with the expected two-year sensitivity to the half-life for neutrinoless double beta decay of 6.4 x 10{sup 25} years. According to the most recent nuclear matrix element calculations, this corresponds to an effective Majorana neutrino mass of 0.13 to 0.19 eV. It will also measure the two neutrino mode for the first time in {sup 136}Xe.

  8. Comment: 200 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available 合データベースセンター) Photo: Takeru Nakazato (Database Center for Life Science) nakazato 2009/11/04 17:26:47 2010/01/14 20:11:35 ... ...Japanese tree frog Hyla japonica Hyla_japonica_L.png 200.png Takeru Nakazato (Database Center for Life Scien...ce) licensed under CC Attribution2.1 Japan ニホンアマガエル Hyla japonica 撮影:仲里猛留(ライフサイエンス統

  9. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  10. Production of Astatine-211 at the Duke University Medical Center for its regional distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, Michael [Duke University Medical Center, Durham, NC (United States)

    2016-01-01

    major subsystems that comprise the CS-30 Cyclotron. With these modifications in place, routine production of ≥200 mCi of At-211 should be readily achievable, given our methodological development of At-211 target preparation, internal target irradiation and dry distillation to recover the radionuclide.

  11. The BAIKAL Neutrino Experiment: From NT200 to NT200+

    CERN Document Server

    Wischnewski, R

    2006-01-01

    The Baikal Neutrino Telescope has been operating in its NT200 configuration since April, 1998. The telescope has been upgraded in April, 2005, to the 10 Mton scale detector NT200+. It's main physics goal is the detection of signals from high energy neutrino cascades. NT200+ reaches a 3-year sensitivity of 2 \\times 10^{-7}cm^{-2}s^{-1}sr^{-1}GeV for an all-flavor diffuse cosmic E^{-2} neutrino flux for energies 10^2 TeV \\div 10^5 TeV. Desgin and sensitivity of NT200+ are described. NT200+ is forming the basic building block of a future km3-scale (Gigaton-Volume) Baikal Telescope. Research and development work on that next stage detector has started.

  12. Hanford 200 Areas Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Rinne, C.A.; Daly, K.S.

    1993-08-01

    The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas.

  13. Catch tanks inhibitor addition 200-East and 200-West Areas

    International Nuclear Information System (INIS)

    Reported is the study of 11 catch tanks in the 200-East Area and the 7 catch tanks in the 200-West Area listed as active. The location, capacity, material of construction, annual total accumulation, annual rain intrusion, waste transfer rate, and access for chemical injection in these tanks are documented. The present and future utilization and isolation plans for the catch tanks are established

  14. FIN 200 (UOP) course tutorial/tutorialoutlet

    OpenAIRE

    naresh 1

    2015-01-01

    For more course tutorials visit www.tutorialoutlet.com     FIN 200 Week 1 CheckPoint Financial Management Goals (UOP) FIN 200 Week 1 Assignment Cash Flow Preparation (UOP) FIN 200 Week 2 Checkpoint Financial Ratios (UOP) FIN 200 Week 2 DQ 1 & DQ 2 (UOP) FIN 200 Week 3 CheckPoint Financial Forecasting (UOP) FIN 200 Week 3 Assignment Pro Forma Statements (UOP) FIN 200 Week 4 Checkpoint Break Even Analysis (UOP) FIN 200 Week 4 DQ 1 & ...

  15. CJS 200 UOP Course Tutorial/ Tutorialrank

    OpenAIRE

    SICENK

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 3 Times, Rating: A+   CJS 200 Assignment: The Prison System CJS 200 Assignment: The Effects of Punishment and Sentencing CJS 200 CheckPoint: Prison Populations CJS 200 Assignment: Inside Criminal Law CJS 200 CheckPoint: Causation of Crime CJS 200 CheckPoint: Law Enforcement Agencies CJS 200 Assignment: The Rules of Law Enforcement CJS 200 CheckPoint: Terrorism and Cyber Cr...

  16. FIN 200 UOP COURSE Tutorial/UOPHELP

    OpenAIRE

    sdfghj

    2015-01-01

    For more course tutorials visit www.uophelp.com   FIN 200 Week 1 CheckPoint Financial Management Goals FIN 200 Week 1 Assignment Cash Flow Preparation FIN 200 Week 2 Checkpoint Financial Ratios FIN 200 Week 2 DQ 1 & DQ 2 FIN 200 Week 3 CheckPoint Financial Forecasting FIN 200 Week 3 Assignment Pro Forma Statements FIN 200 Week 4 Checkpoint Break Even Analysis FIN 200 Week 4 DQ 1 & DQ 2 FIN 200 Week 5 CheckPoint Long-Term and Short-Term Financin...

  17. AED 200 UOP course/uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   AED 200 Week 1 DQ1 and DQ2 AED 200 Week 1 CheckPoint Teacher Certification Licensure AED 200 Week 2 CheckPoint Students Social Challenges AED 200 Week 2 CheckPoint Social Justice AED 200 Week 2 Assignment Multicultural Education Scenario AED 200 Week 3 DQ 1 and DQ 2 AED 200 Week 3 CheckPoint School Funding Issues AED 200 Week 4 CheckPoint Religion in Schools AED 200 Week 4 CheckPoint Debate Proj...

  18. 150V/200V MOSFET

    Institute of Scientific and Technical Information of China (English)

    刘广荣

    2009-01-01

    据《世界电子元器件》2009年9月月刊报道,IR推出一系列150 V和200 VHEXFET功率MOSFET,为开关模式电源(SMPS)、不断电系统(UPS)、反相器和DC马达驱动器等工业应用提供极低的闸电荷(Qg)。随着DC/DC功率转换应用技术的日益进步,开关频率也有所提高,输入电

  19. 20 CFR 416.200 - Introduction.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all...

  20. 21 CFR 1271.200 - Equipment.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Equipment. 1271.200 Section 1271.200 Food and... CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.200 Equipment. (a) General. To prevent the introduction, transmission, or spread of communicable diseases, equipment used in...

  1. 4 CFR 200.7 - Fees.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Fees. 200.7 Section 200.7 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.7 Fees. A fee will not be charged for searching, reviewing, or making corrections to records. A fee for copying will be assessed at the same rate...

  2. 17 CFR 200.310 - Fees.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Fees. 200.310 Section 200.310... Maintained by the Commission § 200.310 Fees. (a) A request by an individual for copies of a record pertaining... the copier and the Commission. (b) Waiver or reduction of fees. Whenever the Privacy Act...

  3. 34 CFR 200.81 - Program definitions.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Program definitions. 200.81 Section 200.81 Education... Program § 200.81 Program definitions. The following definitions apply to programs and projects operated under subpart C of this part: (a) Agricultural work means the production or initial processing of...

  4. 40 CFR 240.200-1 - Requirement.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.200-1 Section 240.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1...

  5. 34 CFR 200.42 - Corrective action.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Corrective action. 200.42 Section 200.42 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.42 Corrective action. (a) Definition. “Corrective action” means action by an LEA that— (1) Substantially and directly responds to—...

  6. 34 CFR 200.17 - Intermediate goals.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Intermediate goals. 200.17 Section 200.17 Education... Programs Operated by Local Educational Agencies Adequate Yearly Progress (ayp) § 200.17 Intermediate goals. Each State must establish intermediate goals that increase in equal increments over the period...

  7. 49 CFR 179.200-10 - Welding.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Welding. 179.200-10 Section 179.200-10... Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-10 Welding. (a) All joints... W (IBR, see § 171.7 of this subchapter). Welding procedures, welders and fabricators shall...

  8. 17 CFR 200.552 - NEPA planning.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false NEPA planning. 200.552 Section 200.552 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... § 200.552 NEPA planning. Where it is reasonably foreseeable by the Commission that it may be required...

  9. 49 CFR 195.200 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.200 Section 195.200 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.200 Scope. This subpart prescribes minimum requirements for constructing...

  10. 17 CFR 200.401 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Definitions. 200.401 Section 200.401 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Regulations Pertaining to Public Observation of Commission Meetings § 200.401 Definitions. As used in...

  11. 14 CFR 1259.200 - Description.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Description. 1259.200 Section 1259.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NATIONAL SPACE GRANT COLLEGE AND FELLOWSHIP PROGRAM Space Grant Program and Project Awards § 1259.200 Description. Awards are authorized...

  12. 34 CFR 200.43 - Restructuring.

    Science.gov (United States)

    2010-07-01

    ...— (1) Makes fundamental reforms to improve student academic achievement in the school; (2) Has... governance, in order to improve student academic achievement in the school and that has substantial promise... 34 Education 1 2010-07-01 2010-07-01 false Restructuring. 200.43 Section 200.43...

  13. 17 CFR 200.64 - Judicial review.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Judicial review. 200.64... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.64 Judicial review. The Congress has provided for review by the courts of the decisions and orders by this Commission. Members should...

  14. 17 CFR 200.505 - Original classification.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Original classification. 200...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Classification and Declassification of National Security Information and Material § 200.505 Original classification. (a) No Commission Member or employee has...

  15. 17 CFR 200.506 - Derivative classification.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Derivative classification. 200...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Classification and Declassification of National Security Information and Material § 200.506 Derivative classification. Any document that includes...

  16. 24 CFR 960.200 - Purpose.

    Science.gov (United States)

    2010-04-01

    ... 960, subpart E. (8) Protection for victims of domestic violence, dating violence, and stalking, 24 CFR... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Purpose. 960.200 Section 960.200 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE...

  17. 7 CFR 1206.200 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Terms defined. 1206.200 Section 1206.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH,...

  18. 7 CFR 1209.200 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Terms defined. 1209.200 Section 1209.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH,...

  19. 44 CFR 206.200 - General.

    Science.gov (United States)

    2010-10-01

    ... to State and Local Governments,” published at 44 CFR part 13, place requirements on the State in its... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false General. 206.200 Section 206.200 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF...

  20. 21 CFR 1311.200 - Pharmacy responsibilities.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Pharmacy responsibilities. 1311.200 Section 1311... ORDERS AND PRESCRIPTIONS (Eff. 6-1-10) Electronic Prescriptions § 1311.200 Pharmacy responsibilities. (a) Before initially using a pharmacy application to process controlled substance prescriptions, the...

  1. 42 CFR 400.200 - General definitions.

    Science.gov (United States)

    2010-10-01

    ... the health insurance program for the aged and disabled under title XVIII of the Act. NCD stands for.... Secretary means the Secretary of Health and Human Services. SNF stands for skilled nursing facility. Social... 42 Public Health 2 2010-10-01 2010-10-01 false General definitions. 400.200 Section 400.200...

  2. 24 CFR 200.78 - Energy conservation.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Energy conservation. 200.78 Section... Eligibility Requirements for Existing Projects Property Requirements § 200.78 Energy conservation... conservation in accordance with standards established by the Commissioner. Mortgage Provisions...

  3. 13 CFR 130.200 - Eligible entities.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Eligible entities. 130.200 Section 130.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS DEVELOPMENT... or university; (3) A college or school of business, engineering, commerce or agriculture; (4)...

  4. 46 CFR 119.200 - General.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false General. 119.200 Section 119.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150 PASSENGERS OR WITH OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS MACHINERY INSTALLATION Propulsion Machinery §...

  5. 10 CFR 1021.200 - DOE planning.

    Science.gov (United States)

    2010-01-01

    ... accordance with 40 CFR 1501.2 and this section. In its planning for each proposal, DOE shall include adequate... accordance with 40 CFR 1506.3. ... 10 Energy 4 2010-01-01 2010-01-01 false DOE planning. 1021.200 Section 1021.200 Energy...

  6. 24 CFR 200.73 - Property development.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Property development. 200.73 Section 200.73 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Requirements for Application, Commitment,...

  7. 7 CFR 62.200 - Services.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Services. 62.200 Section 62.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK, MEAT, AND...

  8. 24 CFR 200.635 - Compliance.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Compliance. 200.635 Section 200.635 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA...

  9. 24 CFR 200.600 - Purpose.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Purpose. 200.600 Section 200.600 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA...

  10. 34 CFR 200.71 - LEA eligibility.

    Science.gov (United States)

    2010-07-01

    ... least five percent of the LEA's total population ages 5 to 17 years, inclusive. (d) Education finance... 34 Education 1 2010-07-01 2010-07-01 false LEA eligibility. 200.71 Section 200.71 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY...

  11. 34 CFR 200.52 - LEA improvement.

    Science.gov (United States)

    2010-07-01

    ... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.52 LEA improvement. (a... must— (i) Incorporate strategies, grounded in scientifically based research, that will strengthen... through 200.20; (v) Address— (A) The fundamental teaching and learning needs in the schools of the...

  12. 7 CFR 1710.200 - Purpose.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Purpose. 1710.200 Section 1710.200 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE... borrower's future requirements for energy and capacity. The load forecast of a power supply...

  13. 17 CFR 200.660 - Communications.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Communications. 200.660 Section 200.660 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION... Communications. (a) The agency shall take appropriate steps to ensure effective communication with...

  14. 17 CFR 200.302 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Definitions. 200.302 Section 200.302 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Regulations Pertaining to the Privacy of Individuals and Systems of Records Maintained by the Commission §...

  15. 49 CFR 179.200-7 - Materials.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Materials. 179.200-7 Section 179.200-7 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR TANK...

  16. Result from, and status of, EXO-200

    Science.gov (United States)

    MacLellan, Ryan; EXO-200 Collaboration

    2016-03-01

    EXO-200 has provided one of the most sensitive searches for neutrinoless double-beta decay utilizing 175kg of enriched liquid xenon in an ultra-low background time projection chamber. This detector has demonstrated excellent energy resolution and background rejection capabilities. Using the first two years of data, EXO-200 has set a limit of 1 . 1 ×1025 y at 90% C.L. on the neutrinoless double-beta decay half-life of 136Xe. The experiment has experienced a brief hiatus in data taking during a temporary shutdown of its host facility: the Waste Isolation Pilot Plant. EXO-200 expects to resume data taking in earnest this fall with upgraded detector electronics. Results from the analysis of EXO-200 data and an update on the current status of EXO-200 will be presented.

  17. 7 CFR 205.200 - General.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Organic Production and Handling Requirements § 205.200 General....

  18. 24 CFR 200.610 - Policy.

    Science.gov (United States)

    2010-04-01

    ... GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.610 Policy. It... programs shall pursue affirmative fair housing marketing policies in soliciting buyers and tenants,...

  19. 24 CFR 200.615 - Applicability.

    Science.gov (United States)

    2010-04-01

    ... DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.615 Applicability. The affirmative fair housing marketing requirements, as set forth in paragraphs (a) through...

  20. Gogol 200 : teatraliseeritud kirjandustund / Reet Kudu

    Index Scriptorium Estoniae

    Kudu, Reet, 1949-

    2009-01-01

    4. aprillil Tallinnas Vene Kultuurikeskuses toimunud teatriõhtust "200 aastat koos Nikolai Gogoliga", mille stsenarist on Lidia Golovataja ja režissöör Jevgeni Gaitšuk. Loe ka: Kes on geeniuse sõbrad?

  1. 200 Irish students at CERN - virtually!

    CERN Multimedia

    2003-01-01

    On 6 October, 200 physics students from schools around Ireland paid a virtual visit to CERN and met several CERN scientists, with the help of the latest video conferencing technology using high-speed internet lines.

  2. The SM-200 step motor control device

    International Nuclear Information System (INIS)

    One of the main nodes of the stand for testing and modeling solenoid coils, which define the focus of the beam of charged particles in the accelerator LUE-200 (IREN), is a device for positioning Hall sensors (HS). The mechanism of movement of the platform where HS are installed is activated by the step motor. This paper describes the control device of the step motor SM-200

  3. Brasil: 200 anos de Estado; 200 anos de administração pública; 200 anos de reformas Brazil: 200 years of state; 200 years of public administration; 200 years of reforms

    Directory of Open Access Journals (Sweden)

    Frederico Lustosa da Costa

    2008-10-01

    Full Text Available A passagem dos 200 anos da transferência da corte portuguesa para o Brasil tem suscitado a realização de inúmeros eventos comemorativos, como seminários, palestras, exposições e a publicação de livros e artigos em jornais e revistas. Entretanto, poucos encontros, discussões e publicações em torno dos "200 anos" procuraram destacar a questão da constituição do Estado nacional e da formação da administração pública brasileira. Este artigo preenche uma pequena parte da lacuna deixada na comemoração do bicentenário da chegada da família real portuguesa ao Brasil. Oferece um rápido panorama da história das transformações por que tem passado a administração pública brasileira, destacando as mudanças planejadas, quer dizer, os esforços de reforma do aparelho de Estado. São enfatizadas as três grandes reformas que se sucederam a partir de meados dos anos 1930 do século passado, separadas entre si por intervalos de 30 anos - 1937, 1967 e 1995 (ou 1998, ano da promulgação da Emenda Constitucional no 19. Todo o percurso percorrido desde 1808 configura hoje uma tríplice efeméride - 200 anos de Estado nacional, 200 anos de administração pública e 200 anos de reformas institucionais e administrativas.The passing of 200 years since the transfer of the Portuguese Royal Court for Brazil has generated the realization of innumerable commemorative events, such as seminars, guest speakers, expositions and the publication of books and articles in journals and magazines. However, few findings, discussions and publications about the "200 years" looked to examine the question of the constitution of the national state and the formation of Brazilian public administration. This article intends to fill the large void left in the commemoration of the 200 years since the arrival of the Royal Portuguese Family in Brazil. It offers a quick historical panorama of the transformations that Brazilian public administration experienced

  4. S-200防空导弹

    Institute of Scientific and Technical Information of China (English)

    刘明

    2008-01-01

    S-200是苏联于上世纪五、六十年代为对付XB-70超音速战略轰炸机和SR-71超音速侦察机而发展出的一种远程中高空防空导弹系统.北约称之为SA-5“甘蒙”(意译为“腌猪腿”)。苏联在1985年时达到装备的最高峰,竟然装备有130个S-200防空导弹团,发射架1950部。随着更新一代的S-300P和S-300V防空导弹系统的服役。S-200才开始陆续退役。

  5. 200 million Euros:Worthy or Not?

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    "Pierre Cardin to Sell Licenses to Chinese Companies with 200 million Euros",frankly speaking,at the first time I knew the news,several questions ran into my mind:"200 million Euros,is it too much for such a not-first-class international fashion brand?","200 millions Euros,with such a large amount of capital,domestic enterprises could gain more investment to develop their own brand?",or"Pierre Cardin…".Although later one of the spokesman of Pierre Cardin Group explained:"This is not about the sale of the Pierre Cardin group,but the sale of certain licenses in China",this hot deal still arouse fierce comments from not only the domestic industrial insiders,but also the publics.

  6. 200mmx200mm OLED步进投影曝光机%Projective Stepper for 200 mmx200 mm OLED Process

    Institute of Scientific and Technical Information of China (English)

    周畅; 李喜峰

    2012-01-01

    It is an undoubted trend for OLED, especially AMOLED, as the next generation and potential display technology. Since producible or profitable AMOLED process has not been mastered by most display manufacturer, 200 mm x200 mm pilot line is very important and cost-efficient for process research and development. And AMOLED process require tighter CD and Overlay for TFT exposure than TFT-LCD. This paper introduces a novel type of projective stepper, SS B200/10A, for TFT procedure of AMOLED pilot line, which is totally different from proximity exposure tool called aligner. Furthermore testing data and display device show the projective stepper can meet well with requirement of AMOLED process.%有机发光二极管(OLED)尤其是AMOLED由于其独特的性能.其可能成为下一代显示技术。目前AMOLED显示还未达到量产之前.200mmx200mm的研发线对于AMOLED技术工艺验证尤为重要。AMOLED对TFT曝光的要求(CD均匀性、套刻精度等)较TFT—LCD高。基于此,介绍了可用于OLED研发要求的步进投影曝光机SSB200/10A,实测数据及显示器件成功开发表明该设备能够很好地满足AMOLED工艺要求。

  7. 200 North Aggregate Area source AAMS report

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This report presents the results of an aggregate area management study (AAMS) for the 200 North Aggregate Area in the 200 Areas of the US Department of Energy (DOE) Hanford Site in Washington State. This scoping level study provides the basis for initiating Remedial Investigation/Feasibility Study (RI/FS) activities under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) or Resource Conservation and Recovery Act (RCRA) Facility Investigations (RFI) and Corrective Measures Studies (CMS) under RCRA. This report also integrates select RCRA treatment, storage, or disposal (TSD) closure activities with CERCLA and RCRA past practice investigations.

  8. 200 North Aggregate Area source AAMS report

    International Nuclear Information System (INIS)

    This report presents the results of an aggregate area management study (AAMS) for the 200 North Aggregate Area in the 200 Areas of the US Department of Energy (DOE) Hanford Site in Washington State. This scoping level study provides the basis for initiating Remedial Investigation/Feasibility Study (RI/FS) activities under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) or Resource Conservation and Recovery Act (RCRA) Facility Investigations (RFI) and Corrective Measures Studies (CMS) under RCRA. This report also integrates select RCRA treatment, storage, or disposal (TSD) closure activities with CERCLA and RCRA past practice investigations

  9. Triggering at ISABELLE: the first 200 nanoseconds

    International Nuclear Information System (INIS)

    In a typical experiment, a certain small number of signals will come into an electronics trailer on cables that are as short as possible and have propagation velocities as high as possible. With these signals a fast decision will be made as to whether the rest of the information coming in on the slower, longer cables should be further processed or not. The typical length of time for this decision is 200 ns. In this paper, some of the problems arising during that first 200 ns are confronted, and some examples of attempts to solve those problems are given

  10. 38 CFR 52.200 - Physical environment.

    Science.gov (United States)

    2010-07-01

    ...) Rehabilitation rooms or an area for individual and group treatments for occupational therapy, physical therapy... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Physical environment. 52...) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.200 Physical...

  11. 17 CFR 200.54 - Constitutional obligations.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Constitutional obligations... ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.54 Constitutional... against any infringement of the constitutional rights, privileges, or immunities of those who are...

  12. 50 CFR 300.200 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Definition of Illegal, Unreported, or Unregulated Fishing § 300.200 Purpose. The purpose of this subpart is... Reauthorization Act of 2006 (“Act”) to publish a definition of the term “Illegal, unreported, or...

  13. 30 CFR 217.200 - Audits.

    Science.gov (United States)

    2010-07-01

    ... copies of audit reports that express opinions on such compliance to the Associate Director for Minerals... INSPECTIONS Coal § 217.200 Audits. An audit of the accounts and books of operators/lessees for the purpose of determining compliance with Federal lease terms relating to Federal royalties may be required annually or...

  14. 36 CFR 200.8 - Appeals.

    Science.gov (United States)

    2010-07-01

    ... submitted under § 200.7 shall be submitted in accordance with U.S. Department of Agriculture rules at 7 CFR... CFR part 1, subpart A, and the appendix to subpart A. (c) The Forest Service Freedom of Information... Agriculture, Auditors Building, 14th and Independence Avenue, S.W., P.O. Box 96090, Washington, DC...

  15. 24 CFR 200.620 - Requirements.

    Science.gov (United States)

    2010-04-01

    ... DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.620... marketing responsibility to another party, be responsible for that party's carrying out the requirements: (a... marketing program shall be in effect for each multifamily project throughout the life of the mortgage....

  16. 17 CFR 200.70 - Business promotions.

    Science.gov (United States)

    2010-04-01

    ... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.70 Business promotions. A member must not engage in any other business, employment or vocation while in office, nor may he ever use the... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Business promotions....

  17. 24 CFR 200.105 - Mortgagor supervision.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Mortgagor supervision. 200.105... supervision. (a) As long as the Commissioner is the insurer or holder of the mortgage, the Commissioner shall... Regulatory Agreement or other instrument granting the Commissioner supervision of the mortgagor....

  18. Uitgelicht: Familienamen en 200 jaar burgerlijke stand.

    NARCIS (Netherlands)

    Brouwer, L.

    2011-01-01

    Dit jaar bestaat de burgerlijke stand 200 jaar en gezien de efficiëntie van de persoonsregistratie die bewerkstelligd is, mogen we daar best stil bij blijven staan. We zien dan ook dat er onder andere op de archieven in den lande uitgebreid aandacht aan wordt besteed. Hier op het Meertens Instituut

  19. 200 aastat klassikalist filoloogiat / Ivo Volt

    Index Scriptorium Estoniae

    Volt, Ivo, 1975-

    2003-01-01

    Detsembris tähistati kollokviumiga 200 a. möödumist klassikalise filoloogia eriala sünnist Eestis. Ettekannetega esinesid ka Mati Unt ja Mari Murdvee (antiikautorite tekstide esitamisvõimalustest teatrilaval), Jüri Talvet ja Jaan Unt

  20. 34 CFR 200.90 - Program definitions.

    Science.gov (United States)

    2010-07-01

    ... Intervention Programs for Children and Youth Who are Neglected, Delinquent, or At-Risk of Dropping Out § 200.90...) in an institution or a community day program for neglected or delinquent children that consists of... community day program or school not operated by the State that serves delinquent children and youth....

  1. 20 CFR 200.6 - Open meetings.

    Science.gov (United States)

    2010-04-01

    ...) Disclose the identity of a confidential source and, in the case of a record compiled by a criminal law...) of this section shall govern in the case of any request under 5 U.S.C. 552 and 20 CFR 200.3 to copy... international tribunal, or an arbitration, or the initiation, conduct, or disposition by the agency of...

  2. 13 CFR 500.200 - Eligible Borrower.

    Science.gov (United States)

    2010-01-01

    ... available to it under reasonable terms or conditions sufficient to meet its financing needs, as reflected in... 500.200 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND... the General Accounting Office and an independent auditor acceptable to the Board prior to the...

  3. 13 CFR 400.200 - Eligible Borrower.

    Science.gov (United States)

    2010-01-01

    ... terms or conditions sufficient to meet its financing needs, as reflected in the financial and business... 400.200 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE... an independent auditor acceptable to the Board prior to the issuance of the guarantee and while...

  4. AED 200 uop course tutorial/uop help

    OpenAIRE

    baily

    2015-01-01

     For more course tutorials visit www.uophelp.com   AED 200 Week 1 DQ1 and DQ2 AED 200 Week 1 CheckPoint Teacher Certification Licensure AED 200 Week 2 CheckPoint Students Social Challenges AED 200 Week 2 CheckPoint Social Justice AED 200 Week 2 Assignment Multicultural Education Scenario AED 200 Week 3 DQ 1 and DQ 2 AED 200 Week 3 CheckPoint School Funding Issues AED 200 Week 4 CheckPoint Religion in Schools AED 200 Week 4 CheckPoint Debat...

  5. 200 Area treated effluent disposal facility operational test report

    International Nuclear Information System (INIS)

    This document reports the results of the 200 Area Treated Effluent Disposal Facility (200 Area TEDF) operational testing activities. These completed operational testing activities demonstrated the functional, operational and design requirements of the 200 Area TEDF have been met

  6. Neuromuscular Fatigue During 200 M Breaststroke

    Directory of Open Access Journals (Sweden)

    Ana Conceição

    2014-03-01

    Full Text Available The aims of this study were: i to analyze activation patterns of four upper limb muscles (duration of the active and non-active phase in each lap of 200m breaststroke, ii quantify neuromuscular fatigue, with kinematics and physiologic assessment. Surface electromyogram was collected for the biceps brachii, deltoid anterior, pectoralis major and triceps brachii of nine male swimmers performing a maximal 200m breaststroke trial. Swimming speed, SL, SR, SI decreased from the 1st to the 3rd lap. SR increased on the 4th lap (35.91 ± 2.99 stroke·min-1. Peak blood lactate was 13.02 ± 1.72 mmol·l-1 three minutes after the maximal trial. The EMG average rectified value (ARV increased at the end of the race for all selected muscles, but the deltoid anterior and pectoralis major in the 1st lap and for biceps brachii, deltoid anterior and triceps brachii in the 4th lap. The mean frequency of the power spectral density (MNF decreased at the 4th lap for all muscles. These findings suggest the occurrence of fatigue at the beginning of the 2nd lap in the 200m breaststroke trial, characterized by changes in kinematic parameters and selective changes in upper limb muscle action. There was a trend towards a non-linear fatigue state.

  7. Os 200 anos da pilha elétrica The 200 years of the electric pile

    Directory of Open Access Journals (Sweden)

    Aécio Pereira Chagas

    2000-06-01

    Full Text Available In celebration of the 200th anniversary of the electric pile, invented by Alessandro Volta, a synopsis of his letter to The Royal Society (London and of his biography is presented.

  8. On sbottom hadronization at LEP 200

    International Nuclear Information System (INIS)

    The question of the hadronization of the sbottom is of interest for experimental searches. A study concerning this feature is presented for masses accessible at LEP 200 assuming that the sbottom is the lightest squark. Numerical evaluations of the decay modes b-bar1 → bX-bar10 and b-bar1 → bX-bar20 are done by varying the SUSY space parameters M2 and μ. The results obtained allow to assert in which conditions the sbottom hadronizes and which decay dominates. (authors)

  9. Hanford 200 area (sanitary) waste water system

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) Hanford Site is located in southeastern Washington State. The Hanford Site is approximately 1,450 sq. km (560 sq. mi) of semiarid land set aside for activities of the DOE. The reactor fuel processing and waste management facilities are located in the 200 Areas. Over the last 50 years at Hanford dicard of hazardous and sanitary waste water has resulted in billions of liters of waste water discharged to the ground. As part of the TPA, discharges of hazardous waste water to the ground and waters of Washington State are to be eliminated in 1995. Currently sanitary waste water from the 200 Area Plateau is handled with on-site septic tank and subsurface disposal systems, many of which were constructed in the 1940s and most do not meet current standards. Features unique to the proposed new sanitary waste water handling systems include: (1) cost effective operation of the treatment system as evaporative lagoons with state-of-the-art liner systems, and (2) routing collection lines to avoid historic contamination zones. The paper focuses on the challenges met in planning and designing the collection system

  10. Superhigh-resolution 200ppi series TFT-LCDs; Chokoseisai 200ppi ekisho display series

    Energy Technology Data Exchange (ETDEWEB)

    Kawamata, K.; Hirai, H. [Toshiba Corp., Tokyo (Japan)

    2000-02-01

    We have developed a 202 pixels per inch (ppi) thin-film transistor liquid crystal display (TFT-LCD) using low-temperature polycrystalline silicon (LTPS) technology. The superhigh resolution of 202 ppi offers the same image quality as printed matter such as magazines. The 200 ppi series TFT-LCDs are expected to support further developments in such areas as electronic books (e-books) and personal digital-picture viewers. Our lineup of 200 ppi TFT-LCDs includes a 4-inch display with VGA resolution, which is suitable for palmtop-size applications, and a 6.3-inch display with XGA resolution, which is suitable for typical photograph or paperback book-size applications. Larger size LCDs with 200 ppi resolution will be developed. (author)

  11. Summary of the 200x200 GeV μ+-μ- collider working group

    International Nuclear Information System (INIS)

    We report the discussions and some preliminary results from the sessions of the 200x200 GeV μ+-μ- Collider working group. The physics motivation for such a open-quote open-quote medium-energy close-quote close-quote collider is discussed. Possible parameters for such a system are described, and compared with higher-energy systems. Relatively-high luminosities (L∼1033 cm-2s-1) appear possible. Modifications of existing facilities to obtain medium-energy μ+-μ- collisions are discussed. Other discussion topics (μ-p colliders, low-energy μ sources, etc.) are summarized. copyright 1995 American Institute of Physics

  12. Hunting virtual LSPs at LEP 200

    CERN Document Server

    Datta, A; Drees, Manuel; Datta, A; Guchait, M; Drees, M

    1995-01-01

    Relatively light sneutrinos, which are experimentally allowed, may significantly affect the currently popular search strategies for supersymmetric particles by decaying dominantly into an invisible channel. In certain cases the second lightest neutralino may also decay invisibly leading to two extra carriers of missing energy -- in addition to the lightest supersymmetric particle (LSP) \\zi\\ -- the virtual LSPs (VLSPs). It is shown that these VLSPs are allowed in supergravity models with common scalar and gaugino masses at the unification scale for a sizable region of parameter space and are consistent with all constraints derived so far from SUSY searches. The pair production of right handed sleptons, which can very well be the lightest charged SUSY particles in this scenario, at LEP 200 and their decay signatures are discussed. The signal survives kinematical cuts required to remove the standard model background. Charginos are also pair produced copiously if kinematically accessible; they also decay dominant...

  13. Earth Surface Patterns in 200 Years (Invited)

    Science.gov (United States)

    Werner, B.

    2009-12-01

    What kinds of patterns will characterize Earth's surface in 200 years? This question is addressed using a complex systems dynamical framework for distinct levels of description in a hierarchy, in which time scale and spatial extent increase and number of variables decrease with level, and in which levels are connected nonlinearly to each other via self-organization and slaving and linearly to the external environment. Self-organized patterns linking the present to 200 years in the future must be described dynamically on a level with a time scale of centuries. Human-landscape coupling will play a prominent role in the formation of these patterns as population peaks and interactions become nonlinear over these time scales. Three related examples illustrate this approach. First, the response of human-occupied coastlines to rising sea level. Coastlines in wealthy regions develop a spatially varying boom and bust pattern, with response amplified by structures meant to delay the effects of sea level rise. Coastlines in economically disadvantaged regions experience a subdued response, with populations developing a culture of displacement that minimizes human-landscape interactions in a context of scarce resources. Second, the evolution of nation-state borders with degrading ecosystems, declining resource availability and increasing transportation costs. The maintenance of strong borders as selective filtration systems (goods, capital and people) is based on a cost-benefit analysis in which the economic benefits accruing from long distance, globalized resource exploitation are weighed against policing and infrastructure costs. As costs rise above benefits, borders fragment, with a transition to local barriers and conflicts, and mobile peoples moving to resources. Third, trends in urbanization and development of megacities under economic and environmental stress. The pattern of rapid growth of megacities through inward migration, with displaced people occupying high

  14. Dynamic behaviour of S200F beryllium

    International Nuclear Information System (INIS)

    Compression tests have been made on a large scale of strain, strain rate (up to 2000 s-1) and temperature (between 20 C and 300 C). From these experiences, we have calculated a constitutive model for beryllium S200F, which can be used by computer codes. Its formulation is not far from Steinberg, Cochran and Guinan's. But in our case, the influences of temperature and strain rate appear clearly within the expression. To validate our equation, we have used it in a computer code. Its extrapolation for higher strain rates is in good agreement with experiments such as Taylor impact tests or plate impact tests (strain rates greater than 104 s-1). With micrography, we could settle a link between the main strain mode within the material, and the variation of one parameter of the model. Beside the constitutive model, we have shown that shock loaded beryllium behaves in two different ways. If the strain rate is lower than 5.106 s-1, then it is proportional to the squared shock pressure. Beyond, it is a linear function of shock pressure to the power of four. By a spall study on beryllium, we have confirmed that it is excessively fragile. Its fracture is sudden, at a strength near 1 GPa. (author)

  15. Laparoscopic Cholecystectomy: An Experience of 200 cases

    Directory of Open Access Journals (Sweden)

    Sanjay K. Bhasin, J.G. Langer.

    2004-04-01

    Full Text Available The surgical management of gallstones has been revolutionized after the advent of laparoscopiccholecystectomysince 1985/87. This minimally invasive technique has virtually become the goldstandard in the management of cholelithiasis. We share our experience of 200 cases of laparoscopiccholecystectomyperformed in symptomatic cholelithiasis over a period of five years from 1998 to2002 in Govt. Medical College, Jammu. There were 32 males and 168 females in the study group.Maximum age of the patients was 65-yr and minimum 17-yr. Patients with high-risk medical problems;deranged LFT, CBD stones and acute cholecystitis were excluded from this study. Average operationtime was 61.3 minute (40-130 mt, post-operative analgesic used were 3.02 doses per patient (2-15doses, post-operative hospital stay was 4.34 days (2-26 days and time to return to work was 13.2days (10-40 days. Rate of conversion to conventional-cholecystectomy was 4%. There was nomortality and negligible/acceptable morbidity. No complications were observed in the follow up periodranging from 2 weeks to 6 months. The patients were quite satisfied with the outcome of the procedure.

  16. 20 CFR 1010.200 - What is priority of service?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What is priority of service? 1010.200 Section 1010.200 Employees' Benefits OFFICE OF THE ASSISTANT SECRETARY FOR VETERANS' EMPLOYMENT AND TRAINING... of Service § 1010.200 What is priority of service? (a) As defined in section 2(a) of the JVA (38...

  17. 29 CFR 2530.200b-6 - Maritime industry.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory...

  18. 7 CFR 948.200 - Accounting and collections.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Accounting and collections. 948.200 Section 948.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Accounting and Collections § 948.200 Accounting and collections. (a) Each handler's assessment account...

  19. 34 CFR 303.200 - Formula for State allocations.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Formula for State allocations. 303.200 Section 303.200 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... TODDLERS WITH DISABILITIES Procedures for Making Grants to States § 303.200 Formula for State...

  20. 34 CFR 200.34 - Identification for restructuring.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Identification for restructuring. 200.34 Section 200.34... for restructuring. (a) If a school continues to fail to make AYP after one full school year of corrective action under § 200.42, the LEA must prepare a restructuring plan for the school and...

  1. 21 CFR 1404.200 - What is a covered transaction?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false What is a covered transaction? 1404.200 Section 1404.200 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.200 What is a covered transaction? A covered transaction is...

  2. 17 CFR 200.72 - Supervision of internal organization.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision...

  3. 21 CFR 73.200 - Synthetic iron oxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Synthetic iron oxide. 73.200 Section 73.200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.200 Synthetic iron oxide. (a) Identity. (1) The color additive synthetic iron oxide consists of...

  4. Limited field investigation for the 200-UP-1 operable unit

    International Nuclear Information System (INIS)

    The 200-UP-1 Groundwater Operable Unit is located in the southern portion of the 200 West Area on the Hanford Site in Washington State. The operable unit is located adjacent to the 200-ZP-1 Groundwater Operable Unit and underlies a significant part of seven source operable units: 200-RO-1, 200-RO-2, 200-RO-3, 200-RO-4, 200-SS-2, 200-UP-2, and 200-UP-3. Remedial efforts in the 100-ZP-1 Operable Unit focus on addressing volatile organic contamination in the aquifer. The focus of the 200-UP-1 limited field investigation (LFI) is on contaminated aquifer soils and groundwater within its boundary, with the exception of uranium and technetium-99 plumes, which are addressed by an existing 200-UP-1 interim remedial measure (IRM). The LFI approach is driven by general and specific data needs required to refine the site conceptual model and conduct a risk assessment. Activities supporting the LFI include drilling, well construction, sampling and analysis, data validation, geologic and geophysical logging, aquifer testing, measuring depth to water, and evaluating geodetic survey and existing analytical data

  5. 24 CFR 200.153 - Presentation of claim.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Presentation of claim. 200.153 Section 200.153 Housing and Urban Development Regulations Relating to Housing and Urban Development... Claims for Losses § 200.153 Presentation of claim. In the event the insured lender is entitled under...

  6. 4 CFR 200.11 - Maintaining records of disclosure.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Maintaining records of disclosure. 200.11 Section 200.11 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.11 Maintaining records of disclosure. (a) The Board shall maintain a log containing the date, nature, and purposes of each...

  7. 46 CFR 180.200 - Survival craft-general.

    Science.gov (United States)

    2010-10-01

    ... and flotation in 33 CFR part 183, and must meet the stowage, launching, and equipment requirements in... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-general. 180.200 Section 180.200 Shipping...) LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 180.200 Survival craft—general....

  8. 46 CFR 117.200 - Survival craft-general.

    Science.gov (United States)

    2010-10-01

    ... by this subpart. Such boats must meet the requirements for safe loading and flotation in 33 CFR Part... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-general. 117.200 Section 117.200 Shipping... Number and Type of Survival Craft § 117.200 Survival craft—general. (a) Each survival craft required on...

  9. 34 CFR 200.6 - Inclusion of all students.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Inclusion of all students. 200.6 Section 200.6 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of...

  10. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  11. 24 CFR 92.200 - Private-public partnership.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Private-public partnership. 92.200 Section 92.200 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development HOME INVESTMENT PARTNERSHIPS PROGRAM Program Requirements § 92.200 Private-public...

  12. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Market study. 246.200-3 Section 246.200-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by...

  13. 12 CFR 563.200 - Conflicts of interest.

    Science.gov (United States)

    2010-01-01

    ...-OPERATIONS Reporting and Bonding § 563.200 Conflicts of interest. If you are a director, officer, or employee... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Conflicts of interest. 563.200 Section 563.200... savings association; and (b) You must, if you have an interest in a matter or transaction before the...

  14. 19 CFR 200.735-103 - Counseling service.

    Science.gov (United States)

    2010-04-01

    ... specific program elements listed in Office of Government Ethics regulations, 5 CFR 738.203(b). ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Counseling service. 200.735-103 Section 200.735... General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated...

  15. Limited field investigation for the 200-UP-1 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The 200-UP-1 Groundwater Operable Unit is located in the southern portion of the 200 West Area on the Hanford Site in Washington State. The operable unit is located adjacent to the 200-ZP-1 Groundwater Operable Unit and underlies a significant part of seven source operable units: 200-RO-1, 200-RO-2, 200-RO-3, 200-RO-4, 200-SS-2, 200-UP-2, and 200-UP-3. Remedial efforts in the 100-ZP-1 Operable Unit focus on addressing volatile organic contamination in the aquifer. The focus of the 200-UP-1 limited field investigation (LFI) is on contaminated aquifer soils and groundwater within its boundary, with the exception of uranium and technetium-99 plumes, which are addressed by an existing 200-UP-1 interim remedial measure (IRM). The LFI approach is driven by general and specific data needs required to refine the site conceptual model and conduct a risk assessment. Activities supporting the LFI include drilling, well construction, sampling and analysis, data validation, geologic and geophysical logging, aquifer testing, measuring depth to water, and evaluating geodetic survey and existing analytical data.

  16. 49 CFR 179.200-22 - Test of tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Test of tanks. 179.200-22 Section 179.200-22... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-22 Test of tanks. (a)...

  17. 49 CFR 179.200-9 - Compartment tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Compartment tanks. 179.200-9 Section 179.200-9... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-9 Compartment tanks....

  18. Neutral Wind Observations below 200 km altitudes

    Science.gov (United States)

    Watanabe, S.; Abe, T.; Habu, H.; Kakinami, Y.; Larsen, M. F.; Pfaff, R. F., Jr.; Yamamoto, M.

    2015-12-01

    Neutral Wind Observations below 200 km altitudesS. Watanabe1, T. Abe2, H. Habu2, Y. Kakinami3, M. Larsen4, R. Pfaff5, M. Yamamoto6, M-Y. Yamamoto31Hokkaido University/Hokkaido Information University, 2JAXA/ISAS, 3Kochi University of Technology, 4Clemson University, 5NASA/Goddard Space Flight Center, 6Kyoto University, Neutral wind in the thermosphere is one of the key parameters to understand the ionosphere-thermosphere coupling process. JAXA/ISAS successfully launched sounding rockets from Uchinoura Space Center (USC) on September 2, 2007, January 12, 2012, and July 20, 2013, and NASA launched sounding rockets from Kwajalein on May 7, 2013 and from Wallops on July 4, 2013. The rockets installed Lithium and/or TMA canisters as well as instruments for plasma and electric and magnetic fields. The atomic Lithium gases were released at altitudes between 150 km and 300 km in the evening on September 2, 2007, at altitude of ~100 km in the morning on January 12, 2012, at altitude of ~120km in the midnight on July 20, 2013, at altitude between 150 km and 300 km in the evening on May 7, 2013 and at altitude of ~150 km in the noon on July 4, 2013. The Lithium atoms were scattering sunlight by resonance scattering with wavelength of 670nm. However, the Lithium atoms scattered moon light on July 20, 2013. The moon light scattering is the first time to use for thermospheric wind measurement in the midnight. The Lithium clouds/trails and TMA trails showed clearly the neutral wind shears and atmospheric waves at ~150 km altitude in the lower thermosphere for all local time.

  19. VASIMR VX-200 thruster throttling optimization from 30 to 200 kW

    Science.gov (United States)

    Squire, Jared; Olsen, Chris; Chang-Diaz, Franklin; Longmier, Benjamin; Ballenger, Maxwell; Carter, Mark; Glover, Tim; McCaskill, Greg

    2012-10-01

    The VASIMR^ VX-200 experimental plasma thruster incorporates a 40 kW helicon plasma source with a 180 kW Ion Cyclotron Heating (ICH) acceleration stage integrated in a superconducting magnet. Argon propellant mass flow is injected up to 140 mg/s. Rapid plasma start up ( 10^5 liters/s) in a 150 m^3 vacuum chamber achieve performance measurements with the charge exchange mean-free-path greater than 1 m in the background neutral gas (pressure efficiency at 200 kW total power is 72 ± 9%, the ratio of effective jet power to input RF power, with an Isp = 4900 ± 300 seconds (flow velocity of 49 km/s), and an ion flux of 1.7 ± 0.1 x 10^21/s. The thrust increases steadily with power to 5.8 ± 0.4 N until the power is maximized and there is no indication of saturation. The plasma density near the device exit exceeds 10^18 m-3 with a power density over 5 MW/m^2. An extensive study of thruster performance, efficiency and thrust-to-power ratio, as a function of Ar propellant flow rate and ICH-to-helicon RF power ratio has been carried out over a total power range of 30 to 200 kW. Optimized throttling set points are determined. The experimental configuration and results of this study are presented.

  20. 200-BP-5 operable unit treatability test report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The 200-BP-5 Operable Unit was established in response to recommendations presented in the 200 East Groundwater Aggregate Area Management Study Report (AAMSR) (DOE-RL 1993a). Recognizing different approaches to remediation, the groundwater AAMSR recommended separating groundwater from source and vadose zone operable units and subdividing 200 East Area groundwater into two operable units. The division between the 200-BP-5 and 200-PO-1 Operable Units was based principally on source operable unit boundaries and distribution of groundwater plumes derived from either B Plant or Plutonium/Uranium Extraction (PUREX) Plant liquid waste disposal sites.

  1. 200-BP-5 operable unit treatability test report

    International Nuclear Information System (INIS)

    The 200-BP-5 Operable Unit was established in response to recommendations presented in the 200 East Groundwater Aggregate Area Management Study Report (AAMSR) (DOE-RL 1993a). Recognizing different approaches to remediation, the groundwater AAMSR recommended separating groundwater from source and vadose zone operable units and subdividing 200 East Area groundwater into two operable units. The division between the 200-BP-5 and 200-PO-1 Operable Units was based principally on source operable unit boundaries and distribution of groundwater plumes derived from either B Plant or Plutonium/Uranium Extraction (PUREX) Plant liquid waste disposal sites

  2. miR-200 family and its mechanism%miR-200及其作用机制

    Institute of Scientific and Technical Information of China (English)

    苏娟; 张庆瑜

    2011-01-01

    miR-200是一簇与上皮间质转化(EMT)密切相关的微RNA(miRNA)家族,其家族成员包括miR-200a、miR-200b、miR-200c、miR-141及miR-429.miR-200是EMT的主要调节分子并可维持细胞的上皮表型,在EMT的发生和肿瘤的进展过程中发挥重要的作用.%MiR-200 family is a cluster of miRNAs closely linked to EMT. The miR-200 family contains miR-200a, miR-200b, miR-200c, miR-141 and miR-429. Many studies have shown that miR-200 family are key regulators of EMT and determine the epithelial phenotype. They are important to both EMT development and tumor progression. This paper reviews the advancement in the research of miR-200 family and its mechanism.

  3. State Waste Discharge Permit application: 200-W Powerhouse Ash Pit

    Energy Technology Data Exchange (ETDEWEB)

    Atencio, B.P.

    1994-06-01

    As part of the Hanford Federal Facility Agreement and Consent Order negotiations; the US Department of Energy, Richland Operations Office, the US Environmental Protection Agency, and the Washington State Department of Ecology agreed that liquid effluent discharges to the ground on the Hanford Site which affect groundwater or have the potential to affect groundwater would be subject to permitting under the structure of Chapter 173-216 (or 173-218 where applicable) of the Washington Administrative Code, the State Waste Discharge Permit Program. This document constitutes the State Waste Discharge Permit application for the 200-W Powerhouse Ash Pit. The 200-W Powerhouse Ash Waste Water discharges to the 200-W Powerhouse Ash Pit via dedicated pipelines. The 200-W Powerhouse Ash Waste Water is the only discharge to the 200-W Powerhouse Ash Pit. The 200-W Powerhouse is a steam generation facility consisting of a coal-handling and preparation section and boilers.

  4. Super high precision 200 ppi liquid crystal display series; Chokoseido 200 ppi ekisho display series

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    In mobile equipment, in demand is a high precision liquid crystal display (LCD) having the power of expression equivalent to printed materials like magazines because of the necessity of displaying a large amount of information on a easily potable small screen. In addition, with the spread and high-quality image of digital still cameras, it is strongly desired to display photographed digital image data in high quality. Toshiba Corp., by low temperature polysilicone (p-Si) technology, commercialized the liquid crystal display series of 200 ppi (pixels per inch) precision dealing with the rise of the high-precision high-image quality LCD market. The super high precision of 200 ppi enables the display of smooth beautiful animation comparable to printed sheets of magazines and photographs. The display series are suitable for the display of various information services such as electronic books and electronic photo-viewers including internet. The screen sizes lined up are No. 4 type VGA (640x480 pixels) of a small pocket notebook size and No. 6.3 type XGA (1,024x768 pixels) of a paperback size, with a larger screen to be furthered. (translated by NEDO)

  5. 38 CFR 200.5 - Coordination with other authorities.

    Science.gov (United States)

    2010-07-01

    ... authorities. 200.5 Section 200.5 Pensions, Bonuses, and Veterans' Relief ARMED FORCES RETIREMENT HOME... explicitly understood that compliance with NEPA does not substitute for compliance with other environmental authorities, nor does compliance with such other authority substitute for compliance with NEPA....

  6. 10 CFR 490.200 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 490.200 Section 490.200 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Mandatory State Fleet... duty motor vehicles acquired for State fleets be alternative fueled vehicles....

  7. 13 CFR 108.200 - Adequate capital for NMVC Companies.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.200 Adequate capital for NMVC Companies. You must meet the requirements of §§ 108.200-108.230 in order to... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Adequate capital for...

  8. 19 CFR 200.735-118 - Interests of employees' relatives.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Interests of employees' relatives. 200.735-118 Section 200.735-118 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES... of an employee's immediate household means those blood relations who are residents of the...

  9. 29 CFR 1926.200 - Accident prevention signs and tags.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Accident prevention signs and tags. 1926.200 Section 1926... § 1926.200 Accident prevention signs and tags. (a) General. Signs and symbols required by this subpart... reference in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a copy of the...

  10. 7 CFR 1437.108-1437.200 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false 1437.108-1437.200 Section 1437.108-1437.200 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS NONINSURED CROP DISASTER ASSISTANCE...

  11. 17 CFR 200.27 - The Regional Directors.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false The Regional Directors. 200.27... § 200.27 The Regional Directors. Each Regional Director is responsible for executing the Commission's... matters, by the Deputy Director of the Division of Enforcement who is responsible for Regional...

  12. 42 CFR 447.200 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.200 Section 447.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED..., economy, and quality of care....

  13. 49 CFR 179.200-11 - Postweld heat treatment.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Postweld heat treatment. 179.200-11 Section 179.200-11 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS... Postweld heat treatment. When specified in § 179.201-1, after welding is complete, postweld heat...

  14. 21 CFR 200.50 - Ophthalmic preparations and dispensers.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Ophthalmic preparations and dispensers. 200.50... (CONTINUED) DRUGS: GENERAL GENERAL Requirements for Specific Classes of Drugs § 200.50 Ophthalmic... intended for ophthalmic use, including preparations for cleansing the eyes, should be sterile. It...

  15. Waste site grouping for 200 Areas soil investigations

    International Nuclear Information System (INIS)

    The purpose of this document is to identify logical waste site groups for characterization based on criteria established in the 200 Areas Soil Remediation Strategy (DOE-RL 1996a). Specific objectives of the document include the following: finalize waste site groups based on the approach and preliminary groupings identified in the 200 Areas Soil Remediation Strategy; prioritize the waste site groups based on criteria developed in the 200 Areas Soil Remediation Strategy; select representative site(s) that best represents typical and worse-case conditions for each waste group; develop conceptual models for each waste group. This document will serve as a technical baseline for implementing the 200 Areas Soil Remediation Strategy. The intent of the document is to provide a framework, based on waste site groups, for organizing soil characterization efforts in the 200 Areas and to present initial conceptual models

  16. Exceptional results from, and status of, EXO-200

    Science.gov (United States)

    Smith, Erica; EXO-200 Collaboration

    2015-10-01

    EXO-200 has provided one of the most sensitive searches for neutrinoless double-beta decay utilizing 175 kg of enriched liquid xenon in an ultra-low background time projection chamber. This detector has demonstrated excellent energy resolution and background rejection capabilities. Using the first two years of data, EXO-200 has set a limit of 1 . 1 ×1025 y at 90% C.L. on the neutrinoless double-beta decay half-life of Xe136. The experiment has experienced a brief hiatus in data taking during a temporary shutdown of its host facility: the Waste Isolation Pilot Plant. EXO-200 expects to resume data taking in earnest this fall with upgraded detector electronics. Results from the analysis of EXO-200 data and an update on the current status of EXO-200 will be presented.

  17. 21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Prescription drugs; reminder advertisements and... Prescription Drug Consumer Price Listing § 200.200 Prescription drugs; reminder advertisements and reminder labeling to provide price information to consumers. (a) Prescription drug reminder advertisements...

  18. 1992 County Pesticide Use Estimates for 200 Compounds

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset includes information for 200 pesticides on the average amount (pounds) applied to 87 agricultural crops and the acres of crops treated for counties...

  19. Grayscale Alaska Shaded Relief ? 200-Meter Resolution - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The grayscale Alaska shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Alaska at a resolution of 200 meters. The...

  20. 17 CFR 200.41 - Quorum of the Commission.

    Science.gov (United States)

    2010-04-01

    ...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.41 Quorum of the... office; and provided further that on any matter of business as to which the number of members in...

  1. 17 CFR 200.67 - Power to adopt rules.

    Science.gov (United States)

    2010-04-01

    ... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.67 Power to adopt rules. In exercising... rules should never tend to stifle or discourage legitimate business enterprises or activities,...

  2. 200 000 kroonine viga Reformierakonna aruandes / Tarmo Vahter

    Index Scriptorium Estoniae

    Vahter, Tarmo, 1970-

    2008-01-01

    Reformierakonna aruande kohaselt maksis Riigikogu liige Jaanus Rahumägi 200 000 krooni reklaamfirmale Droom. J. Rahumäe väitel ei ole ta firmale maksnud sentigi. Vt. samas intervjuud Jaanus Rahumäega

  3. Grayscale Hawaii Shaded Relief ? 200-Meter Resolution - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The grayscale Hawaii shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Hawaii at a resolution of 200 meters. The...

  4. Color Alaska Shaded Relief ? 200-Meter Resolution - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The color Alaska shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Alaska at a resolution of 200 meters. The NED...

  5. 15 CFR 200.105 - Standard reference data.

    Science.gov (United States)

    2010-01-01

    ... Physical and Chemical Reference Data, published jointly with the American Chemical Society and the American..., PROCEDURES, AND FEES § 200.105 Standard reference data. Data on the physical and chemical properties of...

  6. Aerial Photography and Imagery, Ortho-Corrected - Osceola_200_Ortho

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Orthophotos at a map scale of 1"=200' with one foot ground pixel resolution were produced for Osceola, FL. Orthophotography was collected from DMC 10,000' above...

  7. Characterization of Large Area APDs for the EXO-200 Detector

    Energy Technology Data Exchange (ETDEWEB)

    Neilson, R.; LePort, F.; Pocar, A.; /Stanford U., Phys. Dept.; Kumar, K.; /Massachusetts U., Amherst; Odian, A.; Prescott, C.Y.; /SLAC; Tenev, V.; /Stanford U., Phys. Dept.; Ackerman, N.; /SLAC; Akimov, D.; /Moscow, ITEP; Auger, M.; /Bern U., LHEP; Benitez-Medina, C.; /Colorado State U.; Breidenbach, M.; /SLAC; Burenkov, A.; /Moscow, ITEP; Conley, R.; /SLAC; Cook, S.; /Colorado State U.; deVoe, R.; Dolinski, M.J.; /Stanford U., Phys. Dept.; Fairbank, W., Jr.; /Colorado State U.; Farine, J.; /Laurentian U.; Fierlinger, P.; Flatt, B.; /Stanford U., Phys. Dept. /Bern U., LHEP /Stanford U., Phys. Dept. /Maryland U. /Colorado State U. /Laurentian U. /Carleton U. /SLAC /Maryland U. /Moscow, ITEP /Alabama U. /SLAC /Colorado State U. /Stanford U., Phys. Dept. /Alabama U. /Stanford U., Phys. Dept. /Alabama U. /SLAC /Carleton U. /SLAC /Maryland U. /Moscow, ITEP /Carleton U. /Stanford U., Phys. Dept. /Bern U., LHEP /SLAC /Laurentian U. /SLAC /Maryland U.

    2011-12-02

    EXO-200 uses 468 large area avalanche photodiodes (LAAPDs) for detection of scintillation light in an ultra-low-background liquid xenon (LXe) detector. We describe initial measurements of dark noise, gain and response to xenon scintillation light of LAAPDs at temperatures from room temperature to 169 K - the temperature of liquid xenon. We also describe the individual characterization of more than 800 LAAPDs for selective installation in the EXO-200 detector.

  8. The functionality of canoeists specializing in competitive distance 200 meters.

    Directory of Open Access Journals (Sweden)

    Guo Penchen

    2011-09-01

    Full Text Available The article shows the importance of reactive properties to realize the potential of canoeist of south-east Asia specializing in the 200 meters established on a specialized focus of the training process sprinter. The parameters of functionality of athletes based on integrated aerobic and anaerobic ensure competitive distance of 200 m. They are based on assessing level of aerobic power and capacity of energy supply and properties of the cardiorespiratory system in actively increasing metabolic acidosis.

  9. Pleurodesis by erythromycin, tetracycline, Aerosil™ 200, and erythromycin plus Aerosil™ 200 in a rat model: a preliminary study

    OpenAIRE

    Hashemzadeh Shahryar; Hashemzadeh Khosrow; Mamaghani Kamran; Ansari Elnaz; Aligholipour Raheleh; EJ Golzari Samad; Ghabili Kamyar

    2012-01-01

    Abstract Background None of the current pleurodesing agents fulfil all the criteria for best pleural sclerosant. Therefore, the search for the ideal agent for chemical pleurodesis still continues. The aim of the present study was to compare the effectiveness of erythromycin, tetracycline, Aerosil™ 200 (hydrophilic fumed amorphous silica), and erythromycin plus Aerosil™ 200 in producing pleurodesis in rats. In the present study, talc was not used as a pleurodesing agent due to an unavailabilit...

  10. Pleurodesis by erythromycin, tetracycline, Aerosil™ 200, and erythromycin plus Aerosil™ 200 in a rat model: a preliminary study

    Directory of Open Access Journals (Sweden)

    Hashemzadeh Shahryar

    2012-11-01

    Full Text Available Abstract Background None of the current pleurodesing agents fulfil all the criteria for best pleural sclerosant. Therefore, the search for the ideal agent for chemical pleurodesis still continues. The aim of the present study was to compare the effectiveness of erythromycin, tetracycline, Aerosil™ 200 (hydrophilic fumed amorphous silica, and erythromycin plus Aerosil™ 200 in producing pleurodesis in rats. In the present study, talc was not used as a pleurodesing agent due to an unavailability of its sterile and pure form in Iran. Methods Overall, 75 adult male Spraque-Dawley rats were randomized to 5 treatment groups. Each group received an intrapleural injection via 5 Fr Silastic tubes of one of the following sterile agents: 35mg/kg erythromycin in 2 ml of saline, 35mg/kg tetracycline in 2 ml of saline, 35mg/kg Aerosil™ 200 in 2ml of saline, erythromycin (35mg/kg in 2 ml of saline plus Aerosil™ 200 (35mg/kg in 2 ml of saline, or 2 ml of saline as a control. The animals were euthanized and necropsied 30 days after injection. The pleurae were assessed for macroscopic and microscopic evidence of surrounding inflammation and fibrosis. Results The median macroscopic score in the Aerosil™ 200 group was significantly higher than that in the erythromycin group (P P P  Conclusion This study suggests that Aerosil™ 200 with or without erythromycin may be more potent pleurodesis agent than erythromycin and tetracycline.

  11. Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and Mincle.

    Directory of Open Access Journals (Sweden)

    Siddappa N Byrareddy

    Full Text Available Lectin-like molecules and their receptors are cell surface molecules that have been shown to play a role in either facilitating infection or serving as transporters of HIV/SIV in vivo. The role of these lectin-like molecules in the pathogenesis of HIV/SIV infection continues to be defined. In efforts to gain further insight on the potential role of these lectin-like molecules, our laboratory generated monoclonal antibodies (mAb against the human analogs of rhesus macaque CD200, CD200R and Mincle, since the rhesus macaques are accepted as the most reliable animal model to study human HIV infection. The characterization of the cell lineages from the blood and various tissues of rhesus macaques that express these lectin-like molecules are described herein. Among the mononuclear cells, the cells of the myeloid lineage of rhesus macaques are the predominant cell lineages that express readily detectable levels of CD200, CD200R and Mincle that is similar to the expression of Siglec-1 and Siglec-3 reported by our laboratory earlier. Subset analysis revealed that a higher frequency of the CD14+/CD16- subset from normal rhesus macaques express CD200, CD200R and Mincle. Differences in the frequencies and density of expression of these molecules by the gated population of CD14+ cells from various tissues are noted with PBMC and bone marrow expressing the highest and the mononuclear cells isolated from the colon and ileum expressing the lowest levels. While a significant frequency of pDCs and mDCs express Siglec-1/Siglec-3, a much lower frequency expresses CD200, CD200R and Mincle in PBMCs from rhesus macaques. The mAb against CD200 and CD200R but not Mincle appear to inhibit the infection of macrophage tropic SIV/SHIV in vitro. We conclude that these mAbs may have potential to be used as adjunctive therapeutic agents to control/inhibit SIV/HIV infection.

  12. Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and Mincle.

    Science.gov (United States)

    Byrareddy, Siddappa N; Little, Dawn; Mayne, Ann E; Villinger, Francois; Ansari, Aftab A

    2015-01-01

    Lectin-like molecules and their receptors are cell surface molecules that have been shown to play a role in either facilitating infection or serving as transporters of HIV/SIV in vivo. The role of these lectin-like molecules in the pathogenesis of HIV/SIV infection continues to be defined. In efforts to gain further insight on the potential role of these lectin-like molecules, our laboratory generated monoclonal antibodies (mAb) against the human analogs of rhesus macaque CD200, CD200R and Mincle, since the rhesus macaques are accepted as the most reliable animal model to study human HIV infection. The characterization of the cell lineages from the blood and various tissues of rhesus macaques that express these lectin-like molecules are described herein. Among the mononuclear cells, the cells of the myeloid lineage of rhesus macaques are the predominant cell lineages that express readily detectable levels of CD200, CD200R and Mincle that is similar to the expression of Siglec-1 and Siglec-3 reported by our laboratory earlier. Subset analysis revealed that a higher frequency of the CD14+/CD16- subset from normal rhesus macaques express CD200, CD200R and Mincle. Differences in the frequencies and density of expression of these molecules by the gated population of CD14+ cells from various tissues are noted with PBMC and bone marrow expressing the highest and the mononuclear cells isolated from the colon and ileum expressing the lowest levels. While a significant frequency of pDCs and mDCs express Siglec-1/Siglec-3, a much lower frequency expresses CD200, CD200R and Mincle in PBMCs from rhesus macaques. The mAb against CD200 and CD200R but not Mincle appear to inhibit the infection of macrophage tropic SIV/SHIV in vitro. We conclude that these mAbs may have potential to be used as adjunctive therapeutic agents to control/inhibit SIV/HIV infection. PMID:26468886

  13. 200 Area plateau inactive miscellaneous underground storage tanks locations

    International Nuclear Information System (INIS)

    Fluor Daniel Northwest (FDNW) has been tasked by Lockheed Martin Hanford Corporation (LMHC) to incorporate current location data for 64 of the 200-Area plateau inactive miscellaneous underground storage tanks (IMUST) into the centralized mapping computer database for the Hanford facilities. The IMUST coordinate locations and tank names for the tanks currently assigned to the Hanford Site contractors are listed in Appendix A. The IMUST are inactive tanks installed in underground vaults or buried directly in the ground within the 200-East and 200-West Areas of the Hanford Site. The tanks are categorized as tanks with a capacity of less than 190,000 liters (50,000 gal). Some of the IMUST have been stabilized, pumped dry, filled with grout, or may contain an inventory or radioactive and/or hazardous materials. The IMUST have been out of service for at least 12 years

  14. Generation and detection of ultrabroadband infrared wave exceeding 200 THz

    Directory of Open Access Journals (Sweden)

    Ashida Masaaki

    2013-03-01

    Full Text Available By focusing a hollow-fiber compressed intense 10–fs pulse and its second harmonic in air, an ultrabroadband infrared pulse with a spectral range of 1–200 THz is generated through a plasma. Coherent detection of the signal up to 100 THz is achieved with electro–optic sampling and THz air-breakdown-coherent-detection. The drastic dependence on the orientation of the second harmonic crystal is clarified in a range of 100–200 THz. From these, the whole frequency components are confirmed to be generated from the AC biased plasma and phase-locked.

  15. 200 Areas soil remediation strategy -- Environmental Restoration Program

    International Nuclear Information System (INIS)

    The remediation and waste management activities in the 200 Areas of the Hanford Site (located in Richland, Washington) currently range from remediating groundwater, remediating source units (contaminated soils), decontaminating and decommissioning of buildings and structures, maintaining facilities, managing transuranic, low-level and mixed waste, and operating tank farms that store high-level waste. This strategy focuses on the assessment and remediation of soil that resulted from the discharge of liquids and solids from processing facilities to the ground (e.g., ponds, ditches, cribs, burial grounds) in the 200 Areas and addresses only those waste sites assigned to the Environmental Restoration Program

  16. 200 words you should use chambers address to impress

    CERN Document Server

    Watt, Donald

    2008-01-01

    A manageable way to improve your vocabulary: 200 words common enough to be generally understood, but difficult enough to be misused or neglectedEach term explained fully in everyday languageExamples from reputable sources showing how these words can be used to good effect Ever heard a word you wish you could use? Address to Impress clearly explains the meaning and nuance of 200 words selected by the editors of The Chambers Dictionary for their practical value. Quotes from popular media show each entry in context, and easily confusable words are flagged up to prevent

  17. Plot-processing system in computer U-200, (1)

    International Nuclear Information System (INIS)

    In order to use terminal computer U-200 for plot-processing of experimental data, hardware and basic software have been prepared. The digital plotter, originally for system USC-3 can be used as an output device through the adapter consisting of decoding circuit and plot-driving pulse generator. Six subroutine subprograms were also prepared as basic software for U-200, which are called in FORTRAN langauge from the main routine of application programs: SUBROUTINE PLTSET, ... FACTOR, ... WHERE, ... PLOT, ... SYMBOL, and ... NUMBER. They are similar in functional structure to those for USC-3. (auth.)

  18. 200 West Groundwater Aggregate Area management study report

    International Nuclear Information System (INIS)

    This report presents the results of an aggregate area management study (AAMS) for the 200 West Groundwater Aggregate Area in the 200 Areas of the US Department of Energy (DOE) Hanford Site in Washington State. This scoping level study provides the basis for initiating Remedial Investigation/Feasibility Study (RI/FS) activities under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) or Resource Conservation and Recovery Act (RCRA), Facility Investigations (Rlq) and Corrective Measures Studies (CMS) under RCRA. This report also integrates select RCRA treatment, storage or disposal (TSD) closure activities with CERCLA and RCRA past practice investigations

  19. 200 Area Liquid Effluent Facilities -- Quality assurance program plan

    International Nuclear Information System (INIS)

    This Quality Assurance Program Plan (QAPP) describes the quality assurance and management controls used by the 200 Area Liquid Effluent Facilities (LEF) to perform its activities in accordance with DOE Order 5700.6C. The 200 Area LEF consists of the following facilities: Effluent Treatment Facility (ETF); Treated Effluent Disposal Facility (TEDF); Liquid Effluent Retention facility (LERF); and Truck Loading Facility -- (Project W291). The intent is to ensure that all activities such as collection of effluents, treatment, concentration of secondary wastes, verification, sampling and disposal of treated effluents and solids related with the LEF operations, conform to established requirements

  20. 200-BP-5 operable unit Technical Baseline report

    Energy Technology Data Exchange (ETDEWEB)

    Jacques, I.D.; Kent, S.K.

    1991-10-01

    This report supports development of a remedial investigation/feasibility study work plan for the 200-BP-5 operable unit. The report summarizes baseline information for waste sites and unplanned release sites located in the 200-BP-5 operable unit. The sites were investigated by the Technical Baseline Section of the Environmental Engineering Group, Westinghouse Hanford Company (Westinghouse Hanford). The investigation consisted of review and evaluation of current and historical Hanford Site reports, drawings, and photographs, and was supplemented with recent inspections of the Hanford Site and employee interviews. No field investigations or sampling were conducted.

  1. 200-BP-5 operable unit Technical Baseline report

    International Nuclear Information System (INIS)

    This report supports development of a remedial investigation/feasibility study work plan for the 200-BP-5 operable unit. The report summarizes baseline information for waste sites and unplanned release sites located in the 200-BP-5 operable unit. The sites were investigated by the Technical Baseline Section of the Environmental Engineering Group, Westinghouse Hanford Company (Westinghouse Hanford). The investigation consisted of review and evaluation of current and historical Hanford Site reports, drawings, and photographs, and was supplemented with recent inspections of the Hanford Site and employee interviews. No field investigations or sampling were conducted

  2. 24 CFR 200.161 - Administration of debenture transactions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Administration of debenture... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Mortgage Insurance Procedures and Processing Claims for Losses § 200.161 Administration of debenture transactions. The Secretary of...

  3. Analysis of Numerical Simulation Results of LIPS-200 Lifetime Experiments

    Science.gov (United States)

    Chen, Juanjuan; Zhang, Tianping; Geng, Hai; Jia, Yanhui; Meng, Wei; Wu, Xianming; Sun, Anbang

    2016-06-01

    Accelerator grid structural and electron backstreaming failures are the most important factors affecting the ion thruster's lifetime. During the thruster's operation, Charge Exchange Xenon (CEX) ions are generated from collisions between plasma and neutral atoms. Those CEX ions grid's barrel and wall frequently, which cause the failures of the grid system. In order to validate whether the 20 cm Lanzhou Ion Propulsion System (LIPS-200) satisfies China's communication satellite platform's application requirement for North-South Station Keeping (NSSK), this study analyzed the measured depth of the pit/groove on the accelerator grid's wall and aperture diameter's variation and estimated the operating lifetime of the ion thruster. Different from the previous method, in this paper, the experimental results after the 5500 h of accumulated operation of the LIPS-200 ion thruster are presented firstly. Then, based on these results, theoretical analysis and numerical calculations were firstly performed to predict the on-orbit lifetime of LIPS-200. The results obtained were more accurate to calculate the reliability and analyze the failure modes of the ion thruster. The results indicated that the predicted lifetime of LIPS-200's was about 13218.1 h which could satisfy the required lifetime requirement of 11000 h very well.

  4. 40 CFR 156.200 - Scope and applicability.

    Science.gov (United States)

    2010-07-01

    ... Section 156.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... 170 of this chapter. The requirements addressed in these statements are designed to reduce the risk of... used in the production of agricultural plants on agricultural establishments as defined in § 170.3...

  5. 22 CFR 227.200 - Agency and legislative liaison.

    Science.gov (United States)

    2010-04-01

    ... 227.200 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NEW RESTRICTIONS ON LOBBYING Activities... to an officer or employee of a person requesting or receiving a Federal contract, grant, loan, or cooperative agreement if the payment is for agency and legislative liaison activities not directly related...

  6. 24 CFR 990.200 - Determination of formula amount.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Determination of formula amount... Subsidy § 990.200 Determination of formula amount. (a) General. The amount of operating subsidy that a PHA is eligible for is the difference between its formula expenses (as calculated under subpart C of...

  7. Comparison test of WLS200S-22 (Final)

    DEFF Research Database (Denmark)

    Wagner, Rozenn

    This report presents the result of the test on a sector scanning Windcube WLS200S simulating offshore measurements from a coastal site. A comparison is made between the lidar measurements and those of a cup anemometer and a vane mounted on an on-shore met mast at a distance of 1.6 km....

  8. Russia to invest 200 million Swiss Francs in international accelerator

    CERN Multimedia

    2001-01-01

    Russia will invest 200 million CHF in the LHC project, according to first deputy industry, science and technologies minister. The results of scientific research in the center will be use in various industries, enabling new Russian technologies to enter the world market.

  9. 21 CFR 176.200 - Defoaming agents used in coatings.

    Science.gov (United States)

    2010-04-01

    ... glycol (400) esters of coconut oil fatty acids Polyethylene glycol (400) monooleate Polyethylene glycol... 176.200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... alcohol tert-Butyl alcohol Butyl stearate Castor oil, sulfated, ammonium, potassium, or sodium salt...

  10. 24 CFR 200.75 - Environmental quality determinations and standards.

    Science.gov (United States)

    2010-04-01

    ... § 200.75 Environmental quality determinations and standards. Requirements set forth in 24 CFR part 50, Protection and Enhancement of Environmental Quality, 24 CFR part 51, Environmental Criteria and Standards, 24 CFR part 55, Implementation of Executive Order 11988, Flood Plain Management, and as...

  11. 9 CFR 590.200 - Records and related requirements.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Records and Related Requirements for Eggs and Egg Products Handlers and Related Industries § 590.200 Records and related requirements. (a) Persons engaged in the business of transporting, shipping, or...

  12. 24 CFR 291.200 - Future REO acquisition method.

    Science.gov (United States)

    2010-04-01

    ... business with HUD under 2 CFR part 2424. ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Future REO acquisition method. 291... Sales Procedures § 291.200 Future REO acquisition method. (a) Under this method of property...

  13. 48 CFR 50.200 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.200 Scope of subpart. This subpart implements the Support Anti-terrorism by Fostering Effective Technologies Act of 2002 (SAFETY Act) liability protections to promote development and use of...

  14. 17 CFR 200.735-5 - Securities transactions.

    Science.gov (United States)

    2010-04-01

    ... disqualification, such as those resulting from the automatic reinvestment of dividends, stock splits, stock... disqualification provisions of Rule 6, 17 CFR 200.735-6, and 18 U.S.C. 208 are applicable. (ii) For purposes of... 1940 (15 U.S.C. 80a-2(a)(37)) which become effective pursuant to 17 CFR 230.485(b). (2) Securities of...

  15. 41 CFR 109-50.200 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... related and Federal research equipment to elementary and secondary educational institutions or nonprofit organizations for the purpose of improving math and science curricula or conducting of technical and scientific... 50-SPECIAL DOE DISPOSAL AUTHORITIES 50.2-Math and Science Equipment Gift Program § 109-50.200...

  16. 19 CFR 200.735-105 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Gifts, entertainment, and favors. 200.735-105...-105 Gifts, entertainment, and favors. (a) Except as provided in paragraph (b) of this section, no employee may solicit or accept, directly or indirectly, any gift, gratuity, favor, entertainment, loan,...

  17. 17 CFR 200.15 - Office of International Affairs.

    Science.gov (United States)

    2010-04-01

    ... to international securities markets. OIA facilitates the development of and, where appropriate... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Office of International... Organization § 200.15 Office of International Affairs. (a) The Office of International Affairs (“OIA”)...

  18. 200 MeV RF linac for synchrotron injection

    International Nuclear Information System (INIS)

    Construction has been completed on an electron linear accelerator for the Brookhaven National Laboratory. This accelerator will be used for the injection of a 200 MeV electron beam into a synchrotron for lithography experiments. This paper describes the conceptual design of the linac, its e-gun pulser, and its control and timing systems. 3 figs., ref

  19. 24 CFR 200.36 - Financial reporting requirements.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Financial reporting requirements... Regulations § 200.36 Financial reporting requirements. The mortgagor must comply with the financial reporting requirements in 24 CFR part 5, subpart H....

  20. 17 CFR 200.17 - Chief Management Analyst.

    Science.gov (United States)

    2010-04-01

    ...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.17 Chief Management Analyst. The Chief Management Analyst is responsible to the Executive Director... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Chief Management Analyst....

  1. 48 CFR 915.200 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 915.200 Scope of subpart. The 48 CFR subpart 15.2 is not applicable to Program Opportunity Notices for Commercial Demonstrations (See subpart 917.72) or Program Research and Development Announcements (See...

  2. 20 CFR 401.200 - Blood donor locator service.

    Science.gov (United States)

    2010-04-01

    ... 401.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION PRIVACY AND DISCLOSURE OF OFFICIAL RECORDS... authority under State law relating to the public health or otherwise has the duty or authority under State... received pursuant to the rules in this part and section 1141 of the Social Security Act and related...

  3. 17 CFR 200.735-4 - Outside employment and activities.

    Science.gov (United States)

    2010-04-01

    ... receipt of honoraria is discouraged (See 17 CFR 200.735-4(b)(7)), that rule is not applicable to the... by section 401(a) of Executive Order 11222, they are prohibited by Civil Service Regulations (5 CFR... reimbursement may be accepted for the travel expenses of an employee's spouse or traveling companion unless...

  4. The positioning device of beam probes for accelerator LUE-200

    International Nuclear Information System (INIS)

    The description of a device for the positioning of sliding beam probes which is the part of the beam diagnostic system for the LUE-200 electron linac of IREN installation is presented. The device provides remote control of input-output operation of beam probes of five diagnostic stations established in an accelerating tract and in the beam transportation channel of the accelerator

  5. 17 CFR 200.80 - Commission records and information.

    Science.gov (United States)

    2010-04-01

    ... of the Commission appears below as appendix A to this subpart (17 CFR 200.80a). Most of the records..., information received by or given to the Commission in confidence, or any contents of personnel and medical and... established by an executive order to be kept secret in the interest of national defense or foreign policy,...

  6. Measurement Technology on 200 Liters Barrels of Radioactive Waste

    Institute of Scientific and Technical Information of China (English)

    BAI; Lei; SHAO; Jie-wen; LIU; Da-ming; LIU; Hong-bin; CHENG; Yi-mei; HE; Li-xia; ZHU; Li-qun

    2012-01-01

    <正>The measurement device on 200 liters barrel of radioactive waste is designed following the rule of orderly measurement automatically, by using the technology of non-destructive to measure the mass of radioactive waste produced from fuel cycle. Device objects as shown in Fig. 1, which consists of the

  7. 34 CFR 200.51 - Notice of SEA action.

    Science.gov (United States)

    2010-07-01

    ...) To the extent practicable, in a language that parents can understand. (2) The SEA must provide... community the results of its review under § 200.50, including statistically sound disaggregated results in..., including alternative formats upon request; and (ii) To the extent practicable, in a language that...

  8. 19 CFR 200.735-111 - Gambling, betting, and lotteries.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Gambling, betting, and lotteries. 200.735-111...-111 Gambling, betting, and lotteries. An employee shall not participate, while on Government-owned or... a gambling device, in conducting a lottery or pool, in a game for money or property, or in...

  9. High efficiency 200 TEU container ship developed by CSC

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ After three years operation, the large, energy-efficient, environment-friendly 200 TEU container ship Changjiang developed by China Changjiang National Shipping Group Corporation (CSC) has become an important force in the fleet of container ships in the upper reaches of the Yangtze River in China.

  10. 21 CFR 11.200 - Electronic signature components and controls.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Electronic signature components and controls. 11... SERVICES GENERAL ELECTRONIC RECORDS; ELECTRONIC SIGNATURES Electronic Signatures § 11.200 Electronic signature components and controls. (a) Electronic signatures that are not based upon biometrics shall:...

  11. 12 CFR 411.200 - Agency and legislative liaison.

    Science.gov (United States)

    2010-01-01

    ... 411.200 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES NEW RESTRICTIONS ON LOBBYING... to an officer or employee of a person requesting or receiving a Federal contract, grant, loan, or cooperative agreement if the payment is for agency and legislative liaison activities not directly related...

  12. 19 CFR 200.735-125 - Exemption from restrictions.

    Science.gov (United States)

    2010-04-01

    ... any court, board, commission, or legislative body with respect to matters of fact within the personal... employee's testimony is required in the interest of justice. (2) Statements under penalty of perjury. A... 200.735-125 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES...

  13. 24 CFR 200.625 - Affirmative fair housing marketing plan.

    Science.gov (United States)

    2010-04-01

    ... Regulations § 200.625 Affirmative fair housing marketing plan. Each applicant for participation in FHA housing... information indicating his affirmative fair housing marketing plan to comply with the requirements set forth... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Affirmative fair housing...

  14. 17 CFR 200.23a - Office of Economic Analysis.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Office of Economic Analysis... Organization § 200.23a Office of Economic Analysis. The Office of Economic Analysis is responsible for... Office also assists the Commission's enforcement effort by applying economic analysis and...

  15. Comparative Validity of the Shedler and Westen Assessment Procedure-200

    Science.gov (United States)

    Mullins-Sweatt, Stephanie N.; Widiger, Thomas A.

    2008-01-01

    A predominant dimensional model of general personality structure is the five-factor model (FFM). Quite a number of alternative instruments have been developed to assess the domains of the FFM. The current study compares the validity of 2 alternative versions of the Shedler and Westen Assessment Procedure (SWAP-200) FFM scales, 1 that was developed…

  16. 34 CFR 200.36 - Communication with parents.

    Science.gov (United States)

    2010-07-01

    ... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.36 Communication with parents. (a) Throughout the school improvement process, the State, LEA, or school must communicate with the parents of each child attending the school. (b) The State, LEA, or school must ensure...

  17. 40 CFR 180.200 - Dicloran; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Dicloran; tolerances for residues. 180... PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.200 Dicloran; tolerances for residues. (a) General. (1) Tolerances are established for residues of...

  18. Fission barrier heights in the A ∼ 200 mass region

    Indian Academy of Sciences (India)

    K Mahata

    2015-08-01

    Statistical model analysis is carried out for - and -induced fission reactions using a consistent description for fission barrier and level density in A ∼ 200 mass region. A continuous damping of shell correction with excitation energy is considered. Extracted fission barriers agree well with the recent microscopic–macroscopic model. The shell corrections at the saddle point were found to be insignificant.

  19. CCNA routing and switching study guide exams 100-101, 200-101, and 200-120

    CERN Document Server

    Lammle, Todd

    2013-01-01

    Prepare for the new CCNA exams with this Todd Lammle study guide Cisco author, speaker, and trainer Todd Lammle is considered the authority on all things networking, and his books have sold almost a million copies worldwide. This all-purpose CCNA study guide methodically covers all the objectives of the ICND1 (100-101) and ICND2 (200-101) exams as well as providing additional insight for those taking CCNA Composite (200-120) exam. It thoroughly examines operation of IP data networks, LAN switching technologies, IP addressing (IPv4/IPv6), IP routing technologies, IP services, network device s

  20. CCNA routing and switching review guide exams 100-101, 200-101, and 200-120

    CERN Document Server

    Lammle, Todd

    2013-01-01

    Todd Lammle's focused, concise review guide, updated for the latest CCNA exams CCNA is one of the most sought after certifications for IT professionals. If you're preparing for the CCNA Routing and Switching certification, this Sybex review guide offers the best quick review available. Organized by exam objective, it's the perfect supplement to other learning tools, including the Sybex CCNA Routing and Switching Study Guide (ISBN: 9781118749616). All exam topics from exams 100-101, 200-101, and 200-120 are thoroughly covered, and additional study materials including bonus exams, electronic f

  1. Pathogenicity of Autoantibodies in Anti-p200 Pemphigoid

    Science.gov (United States)

    Beckmann, Tina; Hirose, Misa; Dworschak, Jenny; Recke, Andreas; Ludwig, Ralf J.; Hashimoto, Takashi; Zillikens, Detlef; Schmidt, Enno

    2012-01-01

    Recently, the C-terminus of laminin γ1 has been identified as target antigen in anti-p200 pemphigoid and the disease was renamed as anti-laminin γ1 pemphigoid. However, the pathogenic relevance of these autoantibodies has not yet been demonstrated. Therefore, we employed an ex vivo model of autoantibody-mediated leukocyte-dependent neutrophil activation and dermal-epidermal separation (DES) using cryosections of human skin. We showed that anti-p200 pemphigoid sera (n = 7) induced DES in a time-dependent manner, in contrast to sera from healthy controls. Furthermore, laminin γ1-specific IgG and serum depleted from anti-laminin γ1 reactivity were generated using the recombinant C-terminus of laminin γ1 (LAMC1-term; amino acids 1364 to 1609). Interestingly, both fractions labeled the dermal-epidermal-junction (DEJ) by indirect immunofluorescence microscopy on human foreskin and recognized a 200 kDa protein by immunoblotting with dermal extract. Human and rabbit IgG against LAMC1-cterm failed to attract neutrophils at the DEJ and to induce DES. In contrast, patient serum depleted from LAMC1-cterm reactivity led to the same extent of DES as non-depleted IgG. Repeated injection of rabbit anti-murine LAMC1-cterm IgG into both neonatal and adult C57BL/6mice as well as repetitive immunization of various mouse strains with murine LAMC1-cterm failed to induce macro- and microscopic lesions. In all mice, circulating anti-LAMC1-cterm antibodies were present, but only in some mice, IgG deposits were seen at the DEJ. We conclude that autoantibodies in anti-p200 pemphigoid sera are pathogenic while pathogenicity is not mediated by autoantibodies against laminin γ1. Further studies are needed to identify the pathogenically relevant autoantigen in anti-p200 pemphigoid. PMID:22911854

  2. Feasibility study report for the 200-BP-1 operable unit

    International Nuclear Information System (INIS)

    This feasibility study examines a range of alternatives and provides recommendations for selecting a preferred alternative for remediating contamination at the 200-BP-1 operable unit. The 200-BP-1 operable unit is located in the center of the Hanford Site along the northern boundary of the 200 East Area. The 241-BY Tank Farm is located immediately to the south of the operable unit. 200-BP-1 is a source operable unit with contaminated soils associated primarily with nine inactive cribs (known as the 216-B cribs). These cribs were used for disposal of low-level radioactive liquid waste from U Plant uranium recovery operations, and waste storage tank condensate from the adjacent 241-BY Tank Farm. The cribs used for disposal of U Plant waste were in operation from 1955--1965, and the cribs used for disposal of tank condensate were in operation from 1965--1975. In addition to the cribs, four unplanned releases of radioactive materials have occurred within the operable unit. Contaminated surface soils associated with the unplanned releases have been consolidated over the cribs and covered with clean soil to reduce contaminant migration and exposure. Discharge of wastes to the cribs has resulted in soil and groundwater contamination. The groundwater is being addressed as part of the 200 East Aggregate Area, groundwater operable unit. Contaminated soils at the site can be categorized by the types of contaminants, their distribution in the soil column, and the risk posed by the various potential exposure pathways. Below the clean soil cover, the near surface soils contain low-levels of contamination with cesium-137, radium-226, strontium-90, thorium-228, and uranium. The lifetime incremental cancer risk associated with these soils if they were exposed at the surface is 9x10-5

  3. Feasibility study report for the 200-BP-1 operable unit

    International Nuclear Information System (INIS)

    This feasibility study (FS) examines a range of alternatives and provides recommendations for selecting a preferred altemative for remediating contamination at the 200-BP-1 operable unit. The 200-BP-1 operable unit is located in the center of the Hanford Site along the northern boundary of the 200 East Area. The 241-BY Tank Farm is located immediately to the south of the operable unit. 200-BP-1 is a source operable unit with contaminated soils associated primarily with nine inactive cribs (known as the 216-B cribs). These cribs were used for disposal of low-level radioactive liquid waste from U Plant uranium recovery operations, and waste storage tank condensate from the adjacent 241-BY Tank Farm. The cribs used for disposal of U Plant waste were in operation from 1955--1965, and the cribs used for disposal of tank condensate were in operation from 1965-1975. In addition to the cribs, four unplanned releases of radioactive materials have occurred within the operable unit. Contaminated surface soils associated with the unplanned releases have been consolidated over the cribs and covered with clean soil to reduce contaminant migration and exposure. Discharge of wastes to the cribs has resulted in soil and groundwater contamination. The groundwater is being addressed as part of the 200 East Aggregate Area groundwater operable unit. Contaminated soils at the site can be categorized by the types of contaminants, their distribution in the soil column, and the risk posed by the various potential exposure pathways. Below the clean soil cover, the near surface soils contain low-:levels of contamination with cesium-137, radium-226, strontium-90, thorium-228 and uranium. The lifetime incremental cancer risk associated with these soils if they were exposed at the surface is 9 x 105

  4. Pathogenicity of autoantibodies in anti-p200 pemphigoid.

    Directory of Open Access Journals (Sweden)

    Katerina Vafia

    Full Text Available Recently, the C-terminus of laminin γ1 has been identified as target antigen in anti-p200 pemphigoid and the disease was renamed as anti-laminin γ1 pemphigoid. However, the pathogenic relevance of these autoantibodies has not yet been demonstrated. Therefore, we employed an ex vivo model of autoantibody-mediated leukocyte-dependent neutrophil activation and dermal-epidermal separation (DES using cryosections of human skin. We showed that anti-p200 pemphigoid sera (n = 7 induced DES in a time-dependent manner, in contrast to sera from healthy controls. Furthermore, laminin γ1-specific IgG and serum depleted from anti-laminin γ1 reactivity were generated using the recombinant C-terminus of laminin γ1 (LAMC1-term; amino acids 1364 to 1609. Interestingly, both fractions labeled the dermal-epidermal-junction (DEJ by indirect immunofluorescence microscopy on human foreskin and recognized a 200 kDa protein by immunoblotting with dermal extract. Human and rabbit IgG against LAMC1-cterm failed to attract neutrophils at the DEJ and to induce DES. In contrast, patient serum depleted from LAMC1-cterm reactivity led to the same extent of DES as non-depleted IgG. Repeated injection of rabbit anti-murine LAMC1-cterm IgG into both neonatal and adult C57BL/6mice as well as repetitive immunization of various mouse strains with murine LAMC1-cterm failed to induce macro- and microscopic lesions. In all mice, circulating anti-LAMC1-cterm antibodies were present, but only in some mice, IgG deposits were seen at the DEJ. We conclude that autoantibodies in anti-p200 pemphigoid sera are pathogenic while pathogenicity is not mediated by autoantibodies against laminin γ1. Further studies are needed to identify the pathogenically relevant autoantigen in anti-p200 pemphigoid.

  5. Introducing HiggsBounds 2.0.0

    Energy Technology Data Exchange (ETDEWEB)

    Bechtle, Philip; Weiglein, Georg [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Brein, Oliver [Freiburg Univ. (Germany). Physikalisches Inst.; Heinemeyer, Sven [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); Williams, Karina [Bonn Univ. (Germany). Bethe Center for Theoretical Physics

    2011-01-15

    We introduce version 2.0.0 of the computer program HiggsBounds. The program tests neutral and charged Higgs sectors of arbitrary models against the current exclusion bounds from LEP and the Tevatron. As input, it requires a selection of model predictions, such as Higgs masses, branching ratios, effective couplings and total decay widths. The program uses the expected and observed topological cross section limits from the Higgs searches to determine whether a given parameter scenario of a model is excluded at the 95% C.L. by those searches. Version 2.0.0 includes 39/53 LEP/Tevatron Higgs search analyses, compared to 13/36 in the previous release (1.2.0). Among the newly included analyses are LEP searches for neutral Higgs bosons (H) decaying invisibly or into hadrons, LEP searches via the production modes {tau}{sup +}{tau}{sup -}H and b anti bH, Tevatron searches via t anti tH, and LEP and Tevatron searches for charged Higgs bosons. Also, all Tevatron results presented at the ICHEP'10 are included in version 2.0.0. In this note, we explain the basic ideas behind the implementation of HiggsBounds and provide a list of search topologies implemented in version 2.0.0. Furthermore, we apply HiggsBounds 2.0.0 to (a) determine the allowed Higgs mass range for a simple 4th generation model, (b) update/reproduce LEP/Tevatron Higgs exclusion plots for the MSSM m{sub h}{sup max} benchmark scenario, and (c) show exclusion results for the scalar sector of the Randall-Sundrum model. (orig.)

  6. 76 FR 72858 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Science.gov (United States)

    2011-11-28

    ... cracking of the reinforcement angle and shear web, and doing a detailed inspection for cracking of the STA..., reinforcement angle, and shear web; and of the door stop intercostals at S-14L through S16L. ] FAA's... (69 FR 23646, April 30, 2004), for all Boeing Model 737-200C series airplanes. That AD...

  7. Fact Sheet for KM200 Front-end Electronics

    Energy Technology Data Exchange (ETDEWEB)

    Ianakiev, Kiril Dimitrov [Los Alamos National Laboratory; Iliev, Metodi [Los Alamos National Laboratory; Swinhoe, Martyn Thomas [Los Alamos National Laboratory

    2015-07-08

    The KM200 device is a versatile, configurable front-end electronics boards that can be used as a functional replacement for Canberra’s JAB-01 boards based on the Amptek A-111 hybrid chip, which continues to be the preferred choice of electronics for large number of the boards in junction boxes of multiplicity counters that process the signal from an array of 3He detectors. Unlike the A-111 chip’s fixed time constants and sensitivity range, the shaping time and sensitivity of the new KM200 can be optimized for demanding applications such as spent fuel, and thus could improve the safeguards measurements of existing systems where the A-111 or PDT electronics does not perform well.

  8. Continuing the Operation of EXO-200 at WIPP

    Energy Technology Data Exchange (ETDEWEB)

    Gratta, Giorgio [Stanford Univ., CA (United States)

    2016-02-24

    This grant supported, in part, the operations of the EXO-200 double beta decay experiment at the Waste Isolation Pilot Plant (WIPP) for the period May 1, 2013 to Sept 30, 2015. In this period EXO-200 completed its first phase of data taking, although its operation was disrupted in Feb 2014 by the accidents at WIPP (unrelated to the experiment). The primary goal of the experiment is to search for the very rate (and to date not observed) neutrino-less double beta decay. Such decay, if observed, would shed the light of the quantum-mechanical structure of neutrinos, and the origins of elementary particle masses. Another goal of the detector is to serve as prototype of a larger neutrino-less double beta decay experiment, currently being considered by DOE-OS.

  9. Fission fragment mass distributions in reactions populating 200Pb

    CERN Document Server

    Chaudhuri, A; Ghosh, T K; Banerjee, K; Sadhukhan, Jhilam; Bhattacharya, S; Roy, P; Roy, T; Bhattacharya, C; Asgar, Md A; Dey, A; Kundu, S; Manna, S; Meena, J K; Mukherjee, G; Pandey, R; Rana, T K; Srivastava, V; Dubey, R; Kaur, Gurpreet; Saneesh, N; Sugathan, P; Bhattacharya, P

    2016-01-01

    The fission fragment mass distributions have been measured in the reactions 16O + 184W and 19F+ 181Ta populating the same compound nucleus 200Pb? at similar excitation energies. It is found that the widths of the mass distribution increases monotonically with excitation energy, indicating the absence of quasi-fission for both reactions. This is contrary to two recent claims of the presence of quasi-fission in the above mentioned reactions.

  10. Condensation pool experiments with steam using DN200 blowdown pipe

    Energy Technology Data Exchange (ETDEWEB)

    Laine, J.; Puustinen, M. [Lappeenranta Univ. of Technology (Finland)

    2005-08-01

    This report summarizes the results of the condensation pool experiments with steam using a DN200 blowdown pipe. Altogether five experiment series, each consisting of several steam blows, were carried out in December 2004 with a scaled-down test facility designed and constructed at Lappeenranta University of Technology. The main purpose of the experiments was to increase the understanding of different phenomena in the condensation pool during steam discharge. (au)

  11. Stabilization of 200-atom platinum nanoparticles by organosilane fragments

    KAUST Repository

    Pelzer, Katrin

    2011-04-19

    Three\\'s a charm: Platinum nanoparticles of 2 nm diameter and containing approximately 200 atoms covered with n-octylsilyl groups (see picture, right; Pt blue, Si red, C gray, H turquoise) form when [Pt(dba)2] (dba=dibenzylideneacetone) decomposes in the presence of n-octylsilane. The particles adopt a cuboctahedral structure with an edge length of three atoms. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Hydrogen Plasma Generation with 200 MHz RF Ion Source

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeongtae; Park, Kwangmook; Seo, Dong Hyuk; Kim, Han-Sung; Kwon, Hyeok-Jung; Cho, Yong-Sub [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The ion source for the system is required to be rugged with 2000 hours maintenance free operation time because it is installed in the vessel filled with SF6 gas at the pressure of 10 bar. A 200 MHz RF ion source is considered as an ion source. It is a simple construction and provides long life operation. The specifications of the ion source are 5 kV extraction voltage and 1 mA beam current referenced to the proton. RF ion source has been developed and undergone a performance test. Results of the test are presented. 200 MHz RF ion source is designated and manufactured. First of all test stand test of ion source are set up for a performance test of ion source. It includes a RF ion source, a 200-MHz RF system, beam extraction system, vacuum system, beam extraction system, and beam diagnostic system. At pressure of 1.2E-5 torr, hydrogen plasma is generated with net RF power 70 W. Pyrex tube surrounded by an inductive coil takes the role of vessel and discharge is enhanced with field of permanent magnets.

  13. [Humalog® 200 U/ml KwikPen™].

    Science.gov (United States)

    Scheen, A J

    2015-10-01

    Insulin lispro (Humalog®) was the first short-acting insulin analogue to be indicated for the treatment of diabetes mellitus requiring insulin therapy. After subcutaneous injection, insulin lispro has a more favourable pharmacokinetics/pharmacodynamics profile than human insulin, characterized by a faster resorption and a more rapid and less prolonged glucose-lowering activity. These properties allow a better control of postprandial hyperglycaemia and a reduction of the risk of delayed hypoglycaemia, especially at night. The patient's quality of life is also improved because insulin lispro can be injected within the 15 minutes before meal and even possibly after meal when the amount of food intake is unpredictable. Already commercialized as Humalog® 100 U/ml, insulin lispro is now also available as Humalog® 200 U/ml. A pharmacokinetics/pharmacodynamics study confirmed the bioequivalence of the two formulations, based upon the analysis of both plasma free insulin concentrations and glucose infusion rates to maintain normoglycaemia. Humalog® 200 U/ml is available in a novel disposable 3 ml pen (KwikPen™), with lower glide force and injection volume; thus this new pen is more convenient for the patient compared with the current pen used to inject Humalog® 100 U/ml. The new formulation Humalog® 200 U/ml is indicated in Europe for adult patients with type 1 or type 2 diabetes who require more than 20 units of prandial insulin per day to cover their meals.

  14. Visual system effects of exercise on Mauna Kea at 2,200 and 4,200 meters altitude.

    Science.gov (United States)

    Schmeisser, E T; Gagliano, D L; Santiago-Marini, J

    1997-03-01

    Field exercise studies were performed at two altitudes (2,200 and 4,200 m) in 2 successive years using different sets of young male volunteers. Visual function indices were measured both at sea level and during a strenuous exercise regime at altitude. Volunteers were grouped in the first study by initial rest period (2 days vs. no rest) and in the second by diet (supplemental carbohydrates vs. Meals Ready to Eat rations only). Overall results showed no effect according to grouping, a decrease in average visual acuity at the higher altitude overall, and a decrease in electroretinographic (ERG) photopic flicker responses at moderate altitude. It is concluded that heavy exercise at these altitudes may not have operationally significant effects on ground troops in night vision or target recognition, although the change in ERG parameters does indicate a shift in retinal cone physiology that may have subtler effects.

  15. The JHP 200-MeV proton linear accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Takao [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)

    1997-11-01

    A 200-MeV proton linear accelerator for the Japanese Hadron Project (JHP) has been designed. It consists of a 3-MeV radio-frequency quadrupole linac (RFQ), a 50-MeV drift tube linac (DTL) and a 200-MeV separated-type drift tube linac (SDTL). A frequency of 324 MHz has been chosen for all of the rf structures. A peak current of 30 mA (H{sup -} ions) of 400 {mu}sec pulse duration will be accelerated at a repetition rate of 25 Hz. A future upgrade plan up to 400 MeV is also presented, in which annular-coupled structures (ACS) of 972 MHz are used in an energy range of above 150 or 200 MeV. One of the design features is its high performance for a beam-loss problem during acceleration. It can be achieved by separating the transition point in the transverse motion from that of the longitudinal motion. The transverse transition at a rather low-energy range decreases the effects of space-charge, while the longitudinal transition at a rather high-energy range decreases the effects of nonlinear problems related to acceleration in the ACS. Coupled envelope equations and equipartitioning theory are used for the focusing design. The adoption of the SDTL structure improves both the effective shunt impedance and difficulties in fabricating drift tubes with focusing magnets. An accurate beam-simulation code on a parallel supercomputer was used for confirming any beam-loss problem during acceleration. (author)

  16. Radiation emission from the "Rhodotron-TT200" cavity

    Institute of Scientific and Technical Information of China (English)

    Farshid Tabbakh; Mahmud Borhani

    2011-01-01

    In this paper, the X-rays emitted from the Rhodotron-TT200 cavity have been studied in depth.We found that the Bremsstrahlung interaction is the only contribution of X-ray generation important to safety.The X-ray dose rate in the Rhodotron vault is calculated for normal conditions based on MCNP4C results.The presented calculation shows good agreement with the experimental measurements, which consequently confirms the reliability of the calculation for use in shielding design and other safety aspects.

  17. POLYSHIFT Communications Software for the Connection Machine System CM-200

    Directory of Open Access Journals (Sweden)

    William George

    1994-01-01

    Full Text Available We describe the use and implementation of a polyshift function PSHIFT for circular shifts and end-offs shifts. Polyshift is useful in many scientific codes using regular grids, such as finite difference codes in several dimensions, and multigrid codes, molecular dynamics computations, and in lattice gauge physics computations, such as quantum chromodynamics (QCD calculations. Our implementation of the PSHIFT function on the Connection Machine systems CM-2 and CM-200 offers a speedup of up to a factor of 3–4 compared with CSHIFT when the local data motion within a node is small. The PSHIFT routine is included in the Connection Machine Scientific Software Library (CMSSL.

  18. State waste discharge permit application, 200-E chemical drain field

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    As part of the Hanford Federal Facility Agreement and Consent Order negotiations (Ecology et al. 1994), the US Department of Energy, Richland Operations Office, the US Environmental Protection Agency, and the Washington State Department of Ecology agreed that liquid effluent discharges to the ground on the Hanford Site which affect groundwater or have the potential to affect ground would be subject to permitting under the structure of Chapter 173-216 (or 173-218 where applicable) of the Washington Administrative Code, the State Waste Discharge Permit Program. As a result of this decision, the Washington State Department of Ecology and the US Department of Energy, Richland Operations Office entered into Consent Order No. DE 91NM-177, (Ecology and DOE-RL 1991). The Consent Order No. DE 91NM-177 requires a series of permitting activities for liquid effluent discharges. This document presents the State Waste Discharge Permit (SWDP) application for the 200-E Chemical Drain Field. Waste water from the 272-E Building enters the process sewer line directly through a floor drain, while waste water from the 2703-E Building is collected in two floor drains, (north and south) that act as sumps and are discharged periodically. The 272-E and 2703-E Buildings constitute the only discharges to the process sewer line and the 200-E Chemical Drain Field.

  19. Safety analysis, 200 Area, Savannah River Plant: Separations area operations

    International Nuclear Information System (INIS)

    The nev HB-Line, located on the fifth and sixth levels of Building 221-H, is designed to replace the aging existing HB-Line production facility. The nev HB-Line consists of three separate facilities: the Scrap Recovery Facility, the Neptunium Oxide Facility, and the Plutonium Oxide Facility. There are three separate safety analyses for the nev HB-Line, one for each of the three facilities. These are issued as supplements to the 200-Area Safety Analysis (DPSTSA-200-10). These supplements are numbered as Sup 2A, Scrap Recovery Facility, Sup 2B, Neptunium Oxide Facility, Sup 2C, Plutonium Oxide Facility. The subject of this safety analysis, the, Plutonium Oxide Facility, will convert nitrate solutions of 238Pu to plutonium oxide (PuO2) powder. All these new facilities incorporate improvements in: (1) engineered barriers to contain contamination, (2) barriers to minimize personnel exposure to airborne contamination, (3) shielding and remote operations to decrease radiation exposure, and (4) equipment and ventilation design to provide flexibility and improved process performance

  20. Hydrogeology of the 200 Areas low-level burial grounds

    International Nuclear Information System (INIS)

    This report presents information derived from the installation of 35 ground-water monitoring wells around six low-level radioactive/hazardous waste burial grounds located in the 200 Areas of the Hanford Site in southeastern Washington State. This information was collected between May 20, 1987 and August 1, 1988. The contents of this report have been divided into two volumes. This volume contains the main text. Volume 2 contains the appendixes, including data and supporting information that verify content and results found in the main text. This report documents information collected by the Pacific Northwest Laboratory at the request of Westinghouse Hanford Company. Presented in this report are the preliminary interpretations of the hydrogeologic environment of six low-level burial grounds, which comprise four waste management areas (WMAs) located in the 200 Areas of the Hanford Site. This information and its accompanying interpretations were derived from sampling and testing activities associated with the construction of 35 ground-water monitoring wells as well as a multitude of previously existing boreholes. The new monitoring wells were installed as part of a ground-water monitoring program initiated in 1986. This ground-water monitoring program is based on requirements for interim status facilities in compliance with the Resource Conservation and Recovery Act (1976)

  1. Survey of 200 cases of the abdominal aortography

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki Jeung; Choi, Doo Suk; Hah, Hae Koo [National Medical Center, Seoul (Korea, Republic of)

    1972-12-15

    From 1962 to 1970 about 200 abdominal aortographies were performed in Department of Radiology of National Medical Center, Seoul, Korea, with percutaneous retrograde seldinger catheterization technique. The 200 cases of the abdominal aortography were analyzed as followings. 1) The sex ratio of all patients was 105 (52.5%) males to 95 (47.5%) females. And high incidence was noted in middle age group. (46 patients were from 30 years to 40 years of age) 2) Radiological findings were grouped as 62 (31%) vascular lesion, 113 (56.5%) visceral or other expanding lesions and 29 (14.5%) angiographically nonspecific findings. Total is over 200 due to double lesions in 4 patients. 3) The 62 vascular lesions were composed of 40 aortitis, 28 renal hypertension etc. a) The 40 aortitis was divided into 25 artherosclerotic and 15 nonspecific. The 15 nonspecific aortitis revealed segmental narrowing (2-4 cm) with collaterals. b) In 28 renal hypertension, 17 cases were combined with aortitis, but not in 11 cases (Pure renal hypertension), and 19 cases were unilateral. 4) The highest incidence in 113 (56.5%) visceral or other expanding lesions, was renal lesions (88 cases), and other lesions, such as 12 retroperitoneal masses, 9 liver and pancreatic masses were also noted. The 88 renal lesions were composed of 37 renal tbc, 17 hydronephrosis (excluding tbc hydro), Tumors, 10 cyst etc. a) The most significant findings of renal tuberculosis in renal arteriogrpahy was rarefaction of contrast staining in involved area which was noted in 32 cases (87%) out of 37 renal Tuberculosis. b) All 12 hypernephroma, 1 wilm's tumor, metastaic tumor from fibromyomata uteri revealed pathological vessels and tumor stainings, however these findings were not noted in 2 ureteral carcinoma involving renal pelvis. 5) No permanent complications arose after abdominal aortography. (Percutaneous retrograde seldinger catheterization technique) 6) Abdominal aortography and selective visceral injections gave

  2. 200 and 270 GHz SIS receivers development for atmospheric observation

    International Nuclear Information System (INIS)

    Superconducting mixers have been developed for observations of atmospheric minor constituents such as ClO and ozone at Communications Research Laboratory. This paper describes the work at development of 200 and 270 GHz SIS mixers. Nb/AlOx/Nb junctions were fabricated at Nobeyama Radio Observatory. The base Nb layer 200 nm, the Al (AlOx) insulation layer, and the counter Nb electrode 150 nm are sputtered. The area outside of a junction defined by etching of the counter electrode is insulated by anodized Nb layer and sputtered SiO2. After sputtering thick SiO2 layer on the whole wafer, a contact hole is made by etching. The thickness of the wiring Nb layer is 500 nm. The junctions are formed on the 250 μm thick fused quartz substrate. After the process of the junction fabrication, the quartz substrate is shaved from the back side until 150 μm thickness. Each junction for 270 GHz mixer has an area of about 1 μm 2 . The normal resistance of the six junctions series array is around 70 Ω. The mixer block has a reduced waveguide (1.2 x 0.1 mm for 200 GHz and 0.98 x 0. 1 mm for 270 GHz). The waveguide has two tuners in addition to a fixed backshort cavity. This configuration can allow to realize the lower embedding impedance, and less sensitive to the position of the tuners. The SIS mixers are cooled in a closed cycle He refrigerator. The LO is optically injected through a Fabry Perot interferometer. The 5--7 GHz IF is fed to a HEMT amplifier cooled at 15 K. The authors have started a preliminary measurement of the noise temperature of the SIS receivers, and comparing with calculated DSB receiver noise temperature assuming 3-port model. They continue to improve the performance of the SIS mixers now. They intend that the receivers shall be utilized for atmospheric monitor from next winter

  3. miR-200 family and gastrointestinal tumors%miR-200家族在消化系肿瘤中的研究进展

    Institute of Scientific and Technical Information of China (English)

    杜平; 张庆瑜

    2011-01-01

    The miR-200 family (including miR-200a, miR-200b, miR-200c, miR-141, and miR-429) play important roles in proliferation, invasion and metastasis of tumors of epithelial origin. Gastrointestinal tumors belong to a group of tumors of epithelial origin. This article reviews the latest advances in understanding the relationship between the miR-200 family and gastrointestinal tumors.%miR-200家族(miR-200a、miR-200b、miR-200c、miR-141、miR-429)是众多已被发现的mieroRNA中的一员,其在上皮来源肿瘤的增殖、侵袭、转移中的作用成为近年来的研究热点之一,本文对miR-200家族在同为上皮来源的消化系肿瘤中的研究进展进行了综述.

  4. 200 more puzzling physics problems with hints and solutions

    CERN Document Server

    Gnädig, Péter; Vigh, Máté

    2016-01-01

    Like its predecessor, 200 Puzzling Physics Problems, this book is aimed at strengthening students' grasp of the laws of physics by applying them to situations that are practical, and to problems that yield more easily to intuitive insight than to brute-force methods and complex mathematics. The problems are chosen almost exclusively from classical, non-quantum physics, but are no easier for that. They are intriguingly posed in accessible non-technical language, and require readers to select an appropriate analysis framework and decide which branches of physics are involved. The general level of sophistication needed is that of the exceptional school student, the good undergraduate, or the competent graduate student; some physics professors may find some of the more difficult questions challenging. By contrast, the mathematical demands are relatively minimal, and seldom go beyond elementary calculus. This further book of physics problems is not only instructive and challenging, but also enjoyable.

  5. ECFA workshop on LEP 200. Vol. 1 and 2

    International Nuclear Information System (INIS)

    On the initiative of the European Committee for Future Accelerators, a workshop was organized to study experimental and theoretical aspects of the physics feasible at LEP with the beam energy increased to its design value of 100 GeV per beam. These two volumes provide the written versions of the reports presented by nine working groups to the workshop, as well as the presentations on the machine upgrade itself and the potential of hadron colliders and of HERA for LEP 200 physics. Each working group studied a specific topic, evaluating in some detail the requirements both for the detectors and for the machine of W mass measurements, W decay properties, W production dynamics, electroweak radiative corrections, two-photon physics, new heavy quarks and leptons, Higgs particles, supersymmetric particles, and composite models. The proceedings also include some of the more detailed work done in the framework of the working groups. (orig.)

  6. Hydrogen permeation in stationary arc-melted nickel 200

    Science.gov (United States)

    Li, H.; North, T. H.; Sommerville, I. D.; McLean, A.

    1990-06-01

    A combination of hydrogen permeation experiments and computer simulation was used to evaluate the distributions of temperature and of the hydrogen transfer flux in a stationary arcmelted Nickel 200 disc over the entire hydrogen permeation zone. The results indicate that the markedly nonuniform temperature distribution in the hydrogen permeation zone involves widely varying hydrogen fluxes and even transfer of hydrogen in different directions. At steady state, the hydrogen distribution is determined by a thermally produced dynamic equilibrium. Hydrogen supersaturation occurs in solid nickel at the solid/liquid interface in the arc-melted pool. An increase in hydrogen partial pressure in the shielding gas increases the heat input to the melt and decreases the stability of the arc melting process.

  7. High Reflectivity of Silver Extended Down to 200 NM

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, N L; Wolfe, J D

    2001-06-04

    Silver has the highest reflectance of all of the metals, but it tarnishes in the presence of sulfides, chlorides, and oxides in the atmosphere. Also, the silver reflectance is very low at wavelengths below 400 nm making aluminum more desirable mirror coating for the W region. We have found a way to prevent silver tarnishing by sandwiching the silver layer between two thin layers of NiCrN{sub x}, and to extend the metal's high reflectance down to 200 nm by depositing the (thin) Ag layer on top of Al. Thus, the uv is transmitted through the thin Ag layer below 400 nm wavelength, and is reflected from the A1 layer underneath. This W-shifted durable coating provides a valuable alternative to the aluminum coating for telescope mirror coatings where collection efficiency is an important consideration.

  8. Fall 1998 200 East area biological vector contamination report

    Energy Technology Data Exchange (ETDEWEB)

    CONNELL, D.J.

    1999-03-17

    The purpose of this report is to document the investigation into the cause of the spread of radioactive contamination in September and October 1998 at the Hanford Site's 200 East Area and its subsequent spread to the City of Richland Landfill; identify the source of the contamination; and present corrective actions. The focus and thrust of managing the incident was based on the need to accomplish the following, listed in order of importance: (1) protect the health and safety of the Site workers and the public; (2) contain and control the spread of contamination; (3) identify the source of contamination and the pathways for its spread; and (4) identify the causal factors enabling the contamination.

  9. Results of 200 KW fuel cell evaluation programs

    Energy Technology Data Exchange (ETDEWEB)

    Torrey, J.M.; Merten, G.P. [SAIC, San Diego, CA (United States); Binder, M.J. [Army Construction Engineering Research Labs., Champaign, IL (United States)] [and others

    1996-12-31

    Science Applications International Corporation (SAIC) has installed six monitoring systems on ONSI Corporation 200 kW phosphoric acid fuel cells. Three of the systems were installed for the U.S. Army Construction Engineering Research Laboratories (USACERL) which is coordinating the Department of Defense (DoD) fuel cell Demonstration Program and three were installed under a contract with the New York State Energy Research and Development Authority (NYSERDA). Monitoring of the three NYSERDA sites has been completed. Monitoring systems for the DoD fuel cells were installed in August, 1996 and thus no operating data was available at the time of this writing, but will be presented at the Fuel Cell Seminar. This paper will present the monitoring configuration and research approach for each program. Additionally, summary performance data is presented for the completed NYSERDA program.

  10. Fall 1998 200 East area biological vector contamination report

    International Nuclear Information System (INIS)

    The purpose of this report is to document the investigation into the cause of the spread of radioactive contamination in September and October 1998 at the Hanford Site's 200 East Area and its subsequent spread to the City of Richland Landfill; identify the source of the contamination; and present corrective actions. The focus and thrust of managing the incident was based on the need to accomplish the following, listed in order of importance: (1) protect the health and safety of the Site workers and the public; (2) contain and control the spread of contamination; (3) identify the source of contamination and the pathways for its spread; and (4) identify the causal factors enabling the contamination

  11. Optimization of 200 kV electrostatic accelerator

    Directory of Open Access Journals (Sweden)

    M Nazmabadi

    2015-09-01

    Full Text Available Optimizations on 200 kV electrostatic accelerator have been done in order to increasing ion current on target, improving vacuum condition and reduction in x-rays emission, increasing stability of high voltage power supply and reaching much greater achievable voltage value. The accelerator tube has most important effect on beam tracing in the electrostatic accelerators. So precautions most be considered in designing and constructing of this part. In order to finding permissible tolerances in construction and assembling of 200 kV electrostatic accelerator column, first the effects of angle deviation of a part from accelerator axis on beam track in the accelerator tube was simulated with Simion 7.0 computer program. We found that in order to prevent beam lost, the tolerances of balancing and co-centering of each part should be smaller than 0.1 mm. Each part of accelerator tube constructed by tolerances lower than 0.05 mm. Ultrasonic cleaning method used in pre-assembling process of parts. Because of its excellences, in the new tube we used borosilicate glass instead of high density alumina as insulators between the metallic electrodes. After three days of working vacuum pumps the system reached to 8.0×10-7 and after months to 5.0×10-7 ultimate pressure values. Measurements showed that by these considerations the maximum of reachable ion current on target was 1.1 mA which increased 50% compared to old machine, while x-ray emission intensity was increased by 25%. Optimizations of high voltage power supply are now under studies and tests

  12. Laparoscopic repair of hiatal hernias: Experience after 200 consecutive cases

    Directory of Open Access Journals (Sweden)

    Bjelović Miloš

    2014-01-01

    Full Text Available Introduction. Repair of hiatal hernias has been performed traditionally via open laparotomy or thoracotomy. Since first laparoscopic hiatal hernia repair in 1992, this method had a growing popularity and today it is the standard approach in experienced centers specialized for minimally invasive surgery. Objective. In the current study we present our experience after 200 consecutive laparoscopic hiatal hernia repairs. Methods. A retrospective cohort study included 200 patients who underwent elective laparoscopic hiatal hernia repair at the Department for Minimally Invasive Upper Digestive Surgery, Clinic for Digestive Surgery, Clinical Center of Serbia in Belgrade from April 2004 to December 2013. Results. Hiatal hernia types included 108 (54% patients with type I, 30 (15% with type III, 62 (31% with giant paraesophageal hernia, while 27 (13.5% patients presented with a chronic gastric volvulus. There were a total of 154 (77% Nissen fundoplications. In 26 (13% cases Nissen procedure was combined with esophageal lengthening procedure (Collis-Nissen, and in 17 (8.5% Toupet fundoplications was performed. Primary retroesophageal crural repair was performed in 164 (82% cases, Cleveland Clinic Foundation suture modification in 27 (13.5%, 4 (2% patients underwent synthetic mesh hiatoplasty, 1 (0.5% primary repair reinforced with pledgets, and 4 (2% autologous fascia lata graft reinforcement. Poor result with anatomic and symptomatic recurrence (indication for revisional surgery was detected in 5 patients (2.7%. Conclusion. Based on the result analysis, we found that laparoscopic hiatal hernia repair was a technically challenging but feasible technique, associated with good to excellent postoperative outcomes comparable to the best open surgery series.

  13. CKY-200型土工离心机研制%Research and Design of Geotechnical Centrifuge of CKY-200

    Institute of Scientific and Technical Information of China (English)

    刘小刚; 王新伦

    2012-01-01

    The 200g.t geotechnical centrifuge had three layers so that the different systems can be isolatedThe linear motion ball guide was designed between the pull beam and the swing arm supporting, and a monitor system was also designed for the unbalance force.The linkage mechanism can be formed by applying the hinges (pins) between hangers and the swing arm,and the same as between hangers and plat-fomuThus the pitman arm and the tangential exciting force of the shaking table can be weakenedln addition the electric system of the centrifuge has several function modules,such as the static data acquisition system, photo,photography,the dynamic balance system and automatic regulate systeiruFurthermore ,the acceleration control accuracy of the driving system was analyzedThe practical application demonstrates that the stability of the acceleration is less than (±0.5)%F.S/4h and the transmission error of the static data acquisition system is less than 0.015%.%容量为200g.t的CKY-200型土工离心机采用三层布局形式,各系统相对隔离;臂架与转臂支承间采用直线导轨系统联接,并增设不平衡力监测系统;吊篮的吊耳与转臂、吊耳与工作平台间采用铰链(销轴)联接,以削弱安装于吊篮的振动台工作时产生的垂臂向和切向振动冲击.电气系统具备静态数采、摄影、摄像、动平衡检测与自动调整等功能.分析了拖动系统加速度控制精度.试验表明:加速度稳定度≤(±0.5)%F.S/4h;静态数采系统的相对传输误差≤0.015%.

  14. Safety assessment for the proposed pilot-scale treatability tests for the 200-UP-1 and 200-ZP-1 groundwater operable units. Revision 1

    International Nuclear Information System (INIS)

    This safety assessment provides an analysis of the proposed pilot-scale treatability test activities to be and conducted within the 200 Area groundwater operable units on the Hanford Site. The 200-UP-1 and 200-ZP-1 operable units are located in the 200 West Area of the Hanford Site. These tests will evaluate an ion exchange (IX) water purification treatment system and granular activated carbon (GAC). A detailed engineering analysis of (GAC) adsorption for remediation of groundwater contamination. A detailed engineering analysis of the IX treatment system. The principal source of information for this assessment, states that the performance objective of the treatment systems is to remove 90% of the uranium and technetium-99 (99Tc) from the extracted groundwater at the 200-UP-1 site. The performance objective for 200-ZP-1 is to remove 90% of the carbon tetrachloride (CCl4), chloroform, and trichloroethylene (TCE) from the extracted groundwater

  15. The Atacama Cosmology Telescope: CMB Polarization at $200<\\ell<9000$

    CERN Document Server

    Naess, Sigurd; McMahon, Jeff; Niemack, Michael D; Addison, Graeme E; Ade, Peter A R; Allison, Rupert; Amiri, Mandana; Baker, Andrew; Battaglia, Nick; Beall, James A; de Bernardis, Francesco; Bond, J Richard; Britton, Joe; Calabrese, Erminia; Cho, Hsiao-mei; Coughlin, Kevin; Crichton, Devin; Das, Sudeep; Datta, Rahul; Devlin, Mark J; Dicker, Simon R; Dunkley, Joanna; Dünner, Rolando; Fowler, Joseph W; Fox, Anna E; Gallardo, Patricio; Grace, Emily; Gralla, Megan; Hajian, Amir; Halpern, Mark; Henderson, Shawn; Hill, J Colin; Hilton, Gene C; Hilton, Matt; Hincks, Adam D; Hlozek, Renée; Ho, Patty; Hubmayr, Johannes; Huffenberger, Kevin M; Hughes, John P; Infante, Leopoldo; Irwin, Kent; Jackson, Rebecca; Klein, Jeff; Koopman, Brian; Kosowsky, Arthur; Li, Dale; Louis, Thibaut; Lungu, Marius; Madhavacheril, Mathew; Marriage, Tobias A; Maurin, Loïc; Menanteau, Felipe; Moodley, Kavilan; Munson, Charles; Newburgh, Laura; Nibarger, John; Nolta, Michael R; Page, Lyman A; Pappas, Christine; Partridge, Bruce; Rojas, Felipe; Schmitt, Benjamin; Sehgal, Neelima; Sherwin, Blake D; Sievers, Jon; Simon, Sara; Spergel, David N; Staggs, Suzanne T; Switzer, Eric R; Thornton, Robert; Trac, Hy; Tucker, Carole; Van Engelen, Alexander; Ward, Jon; Wollack, Edward J

    2014-01-01

    We report on measurements of the cosmic microwave background (CMB) and celestial polarization at 146 GHz made with the Atacama Cosmology Telescope Polarimeter (ACTPol) in its first three months of observing. Four regions of sky covering a total of 270 square degrees were mapped with an angular resolution of $1.3'$. The map noise levels in the four regions are between 11 and 17 $\\mu$K-arcmin. We present TT, TE, EE, TB, EB, and BB power spectra from three of these regions. The observed E-mode polarization power spectrum, displaying six acoustic peaks in the range $200<\\ell<3000$, is an excellent fit to the prediction of the best-fit cosmological models from WMAP9+ACT and Planck data. The polarization power spectrum, which mainly reflects primordial plasma velocity perturbations, provides an independent determination of cosmological parameters consistent with those based on the temperature power spectrum, which results mostly from primordial density perturbations. We find that without masking any point sou...

  16. Návrh podvozku VUT200 TwinCobra

    OpenAIRE

    Novák, Josef

    2015-01-01

    Hlavním cílem diplomové práce je návrh variant konstrukčního řešení uspořádání a zatahování hlavního podvozku letounu VUT200 TwinCobra. Pro každou variantu je určen rozvor respektive rozchod podvozkových noh v závislosti na poloze hlavního podvozku, která je volena vzhledem k možnostem zatažení podvozku do draku letounu. Pro vybranou variantu jsou sledovány další cíle diplomové práce - určení případů zatížení při přistání podle požadavků předpisu CS 23 a pevnostní analýza dílců podvozkové noh...

  17. ASASSN-14ae: A Tidal Disruption Event at 200 Mpc

    CERN Document Server

    Holoien, Thomas W -S; Bersier, D; Kochanek, C S; Stanek, K Z; Shappee, B J; Grupe, D; Basu, U; Beacom, J F; Brimacombe, J; Brown, J S; Davis, A B; Jencson, J; Pojmanski, G; Szczygiel, D M

    2014-01-01

    ASASSN-14ae is a candidate tidal disruption event (TDE) found at the center of SDSS J110840.11+340552.2 ($d\\simeq200$ Mpc) by the All-Sky Automated Survey for Supernovae (ASAS-SN), a global array of 14-cm telescopes. The host galaxy is an early type spiral with no signs of an active galactic nucleus (AGN) and with little recent star formation. We present follow-up photometric and spectroscopic observations of the source, including optical data from ground-based telescopes and ultraviolet and optical data from Swift. From blackbody fits to the host-subtracted spectral energy distribution, we find that the transient had a peak luminosity of $L\\simeq8\\times10^{43}$ erg s$^{-1}$ and a total integrated energy of $E\\simeq1.5\\times10^{50}$ ergs over the $\\sim3$ months of observations presented. The blackbody temperature of the transient remains roughly constant at $T\\sim20,000$ K while the luminosity declines by nearly 1.5 orders of magnitude during this time, a drop that is most consistent with an exponential, $L\\p...

  18. Computerized tomographic studies in cerebral palsy. Analysis of 200 cases

    Energy Technology Data Exchange (ETDEWEB)

    Sugie, Y. (Tokyo Women' s Medical Coll. (Japan))

    1981-09-01

    Computed tomographic (CT) findings in 200 children with cerebral palsy (CP) were analysed from the viewpoint of clinical manifestations, disease complications and etiological factors. CT scans of 135 cases (67.5%) were found to be abnormal and there were 14 (7%) borderline cases. The major abnormality found on CT scans was cerebral atrophy. Other important changes included focal or diffuse low density area in the brain tissue, congenital malformation, and cerebellar atrophy. From the clinical point of view, a large number of patients with spastic tetraplegia and spastic diplegia showed highly abnormal CT scans. On the other hand, in patients with spastic monoplegia, spastic paraplegia, and athetotic type, CT findings were normal or revealed only minor cerebral atrophy. Most children showing asymmetric clinical symptoms had corresponding asymmetric CT abnormalities which included ventricular enlargement, low density area in the brain tissue, and hemispherical volume. There was a significant correlation between the severity of physical impairment and the extent of CT abnormalities. Severely affected children had grossly abnormal CT scans such as hydranencephaly, polycystic change, and extensive cerebral atrophy. In the patients complicated with epilepsy, the incidence and severity of abnormal CT were higher than those of non-epileptic patients. Mentally retarded patients had variable enlargement of the subarachnoidal space depending on the severity of their mental retardation. Patients with suspected postnatal etiology also had high incidence of severe CT abnormality. CT scan is a valuable tool for evaluating patients with CP and in some cases, possible etiology of the disease may be discovered.

  19. Calibration of the Nikon 200 for Close Range Photogrammetry

    Energy Technology Data Exchange (ETDEWEB)

    Sheriff, Lassana; /City Coll., N.Y. /SLAC

    2010-08-25

    The overall objective of this project is to study the stability and reproducibility of the calibration parameters of the Nikon D200 camera with a Nikkor 20 mm lens for close-range photogrammetric surveys. The well known 'central perspective projection' model is used to determine the camera parameters for interior orientation. The Brown model extends it with the introduction of radial distortion and other less critical variables. The calibration process requires a dense network of targets to be photographed at different angles. For faster processing, reflective coded targets are chosen. Two scenarios have been used to check the reproducibility of the parameters. The first one is using a flat 2D wall with 141 coded targets and 12 custom targets that were previously measured with a laser tracker. The second one is a 3D Unistrut structure with a combination of coded targets and 3D reflective spheres. The study has shown that this setup is only stable during a short period of time. In conclusion, this camera is acceptable when calibrated before each use. Future work should include actual field tests and possible mechanical improvements, such as securing the lens to the camera body.

  20. Applications of magnetic resonance imaging at 200 MHz

    International Nuclear Information System (INIS)

    In this thesis the construction and testing of an NMR microimaging system based on a WM200 console and 4.7T 89mm bore magnet is described. This imaging system was assembled by the author and used for small animal imaging. Good image quality was obtained. NMR imaging of small animals is demonstrated using this system in the brain of the rat and the abdomen of the mouse. The possibility of using NMR imaging in conjunction with the technique of microdialysis is also demonstrated and the ability of the system to monitor the occurrence of lesions in rat brain is explored. In the second part of this, thesis a novel projection gradient coil design, to be used for remote MRI, is introduced and its construction described. Such open systems will widen the medical and non-medical applications of MRI. Simple theoretical solutions for the generation of linear gradients, which may form the basis of future designs, are presented. The practical feasibility of such systems is clearly demonstrated through the construction and refinement of a simple projection gradient system. Finally, the construction and successful testing of a complete remote imaging probe is described. (author)

  1. 41 CFR 301-71.200 - Who must review and sign travel claims?

    Science.gov (United States)

    2010-07-01

    ... travel claims? 301-71.200 Section 301-71.200 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 71-AGENCY TRAVEL ACCOUNTABILITY REQUIREMENTS Travel Claims for Reimbursement § 301-71.200 Who must review and sign travel...

  2. 20 CFR 664.200 - Who is eligible for youth services?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Who is eligible for youth services? 664.200 Section 664.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR YOUTH ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Eligibility for Youth Services § 664.200 Who...

  3. 49 CFR 179.200-19 - Reinforcements, when used, and appurtenances not otherwise specified.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Reinforcements, when used, and appurtenances not otherwise specified. 179.200-19 Section 179.200-19 Transportation Other Regulations Relating to... DOT-111AW and 115AW) § 179.200-19 Reinforcements, when used, and appurtenances not otherwise...

  4. 40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

    Science.gov (United States)

    2010-07-01

    ... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other...

  5. 9 CFR 113.200 - General requirements for killed virus vaccines.

    Science.gov (United States)

    2010-01-01

    ... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus...

  6. 34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.

    Science.gov (United States)

    2010-07-01

    ... action, or restructuring. 200.37 Section 200.37 Education Regulations of the Offices of the Department of... restructuring. (a) If an LEA identifies a school for improvement or subjects the school to corrective action or restructuring, the LEA must, consistent with the requirements of § 200.36, promptly notify the parent or...

  7. 12 CFR 550.200 - Must I review a prospective account before I accept it?

    Science.gov (United States)

    2010-01-01

    ... accept it? 550.200 Section 550.200 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE... § 550.200 Must I review a prospective account before I accept it? Before accepting a prospective fiduciary account, you must review it to determine whether you can properly administer the account....

  8. Laboratory Diagnosis and Clinical Profile of Anti-p200 Pemphigoid

    NARCIS (Netherlands)

    Meijer, Joost M; Diercks, Gilles F H; Schmidt, Enno; Pas, Hendri H; Jonkman, Marcel F

    2016-01-01

    Importance: Anti-p200 pemphigoid is a rare subepidermal autoimmune blistering disease characterized by autoantibodies against a 200-kDa protein in the basement membrane zone. Anti-p200 pemphigoid is probably often misdiagnosed because of low availability of diagnostic assays and expertise and classi

  9. 33 CFR 166.200 - Shipping safety fairways and anchorage areas, Gulf of Mexico.

    Science.gov (United States)

    2010-07-01

    ... Navigation or danger markings must be installed as required by 33 CFR Subchapter C. (c) Special Conditions...: For Federal Register citations affecting § 166.200, see the List of CFR Sections Affected, which... anchorage areas, Gulf of Mexico. 166.200 Section 166.200 Navigation and Navigable Waters COAST...

  10. 21 CFR 200.10 - Contract facilities (including consulting laboratories) utilized as extramural facilities by...

    Science.gov (United States)

    2010-04-01

    ... laboratories) utilized as extramural facilities by pharmaceutical manufacturers. 200.10 Section 200.10 Food and... GENERAL General Provisions § 200.10 Contract facilities (including consulting laboratories) utilized as...) The Food and Drug Administration is aware that many manufacturers of pharmaceutical products...

  11. 17 CFR 200.30-5 - Delegation of authority to Director of Division of Investment Management.

    Science.gov (United States)

    2010-04-01

    ... Director of Division of Investment Management. 200.30-5 Section 200.30-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.30-5 Delegation of authority to Director...

  12. 17 CFR 200.20b - Director of Division of Investment Management.

    Science.gov (United States)

    2010-04-01

    ... Investment Management. 200.20b Section 200.20b Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.20b Director of Division of Investment Management. The Director of the...

  13. 7 CFR 3015.200 - Acknowledgement of support on publications and audiovisuals.

    Science.gov (United States)

    2010-01-01

    ... audiovisuals. 3015.200 Section 3015.200 Agriculture Regulations of the Department of Agriculture (Continued... Miscellaneous § 3015.200 Acknowledgement of support on publications and audiovisuals. (a) Definitions. Appendix A defines “audiovisual,” “production of an audiovisual,” and “publication.” (b)...

  14. 29 CFR 780.200 - Inclusion of forestry or lumbering operations in agriculture is limited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Inclusion of forestry or lumbering operations in agriculture is limited. 780.200 Section 780.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Lumbering Operations § 780.200 Inclusion of forestry or lumbering operations in agriculture is...

  15. 17 CFR 200.18 - Director of Division of Corporation Finance.

    Science.gov (United States)

    2010-04-01

    ... Corporation Finance. 200.18 Section 200.18 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of Corporation Finance is responsible to the Commission for the administration of all matters (except...

  16. Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation

    NARCIS (Netherlands)

    N. Koning; M. van Eijk; W. Pouwels; M.S.M. Brouwer; D. Voehringer; I. Huitinga; R.M. Hoek; G. Raes; J. Hamann

    2010-01-01

    Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-4 or IL-13. In mice, peritoneal M2 macrophage

  17. 17 CFR 200.20c - Office of Filings and Information Services.

    Science.gov (United States)

    2010-04-01

    ... Information Services. 200.20c Section 200.20c Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.20c Office of Filings and Information Services. The Office of Filings and Information Services is responsible for the receipt and initial handling of all public documents filed at...

  18. Altered expression of mRNAs implicated in osteogenesis under conditions of simulated microgravity is regulated by CD200:CD200R

    Science.gov (United States)

    Lee, Lydia; Kos, Olha; Gorczynski, Reginald M.

    2008-12-01

    Mouse calvarial cells grown under simulated microgravity conditions (neutral buoyancy) show preferential differentiation towards the osteoclast lineage, as defined by surrogate mRNAs, bone nodule growth and TRAP+ cells, when compared with cells cultured under normal gravity conditions. This effect was suppressed in cultures which contained the immunoregulatory molecule CD200, and conversely enhanced by anti-CD200 mAb. Concomitant increases occur in expression of inflammatory cytokines, and their mRNAs, under simulated microgravity conditions. Again cultures containing exogenous CD200 showed suppressed cytokine and cytokine mRNA expression. Further alterations in osteoclastogenesis were seen using cells isolated from cytokine-receptor knockout mice. We conclude that, as assessed by altered expression of mRNAs associated with osteoblast differentiation, CD200:CD200R interactions play an important regulatory role in the enhanced osteoclastogenesis seen under simulated microgravity conditions, with changes in cytokine expression further modulating this effect.

  19. PEROXIDE DESTRUCTION TESTING FOR THE 200 AREA EFFLUENT TREATMENT FACILITY

    Energy Technology Data Exchange (ETDEWEB)

    HALGREN DL

    2010-03-12

    The hydrogen peroxide decomposer columns at the 200 Area Effluent Treatment Facility (ETF) have been taken out of service due to ongoing problems with particulate fines and poor destruction performance from the granular activated carbon (GAC) used in the columns. An alternative search was initiated and led to bench scale testing and then pilot scale testing. Based on the bench scale testing three manganese dioxide based catalysts were evaluated in the peroxide destruction pilot column installed at the 300 Area Treated Effluent Disposal Facility. The ten inch diameter, nine foot tall, clear polyvinyl chloride (PVC) column allowed for the same six foot catalyst bed depth as is in the existing ETF system. The flow rate to the column was controlled to evaluate the performance at the same superficial velocity (gpm/ft{sup 2}) as the full scale design flow and normal process flow. Each catalyst was evaluated on peroxide destruction performance and particulate fines capacity and carryover. Peroxide destruction was measured by hydrogen peroxide concentration analysis of samples taken before and after the column. The presence of fines in the column headspace and the discharge from carryover was generally assessed by visual observation. All three catalysts met the peroxide destruction criteria by achieving hydrogen peroxide discharge concentrations of less than 0.5 mg/L at the design flow with inlet peroxide concentrations greater than 100 mg/L. The Sud-Chemie T-2525 catalyst was markedly better in the minimization of fines and particle carryover. It is anticipated the T-2525 can be installed as a direct replacement for the GAC in the peroxide decomposer columns. Based on the results of the peroxide method development work the recommendation is to purchase the T-2525 catalyst and initially load one of the ETF decomposer columns for full scale testing.

  20. PEROXIDE DESTRUCTION TESTING FOR THE 200 AREA EFFLUENT TREATMENT FACILITY

    International Nuclear Information System (INIS)

    The hydrogen peroxide decomposer columns at the 200 Area Effluent Treatment Facility (ETF) have been taken out of service due to ongoing problems with particulate fines and poor destruction performance from the granular activated carbon (GAC) used in the columns. An alternative search was initiated and led to bench scale testing and then pilot scale testing. Based on the bench scale testing three manganese dioxide based catalysts were evaluated in the peroxide destruction pilot column installed at the 300 Area Treated Effluent Disposal Facility. The ten inch diameter, nine foot tall, clear polyvinyl chloride (PVC) column allowed for the same six foot catalyst bed depth as is in the existing ETF system. The flow rate to the column was controlled to evaluate the performance at the same superficial velocity (gpm/ft2) as the full scale design flow and normal process flow. Each catalyst was evaluated on peroxide destruction performance and particulate fines capacity and carryover. Peroxide destruction was measured by hydrogen peroxide concentration analysis of samples taken before and after the column. The presence of fines in the column headspace and the discharge from carryover was generally assessed by visual observation. All three catalysts met the peroxide destruction criteria by achieving hydrogen peroxide discharge concentrations of less than 0.5 mg/L at the design flow with inlet peroxide concentrations greater than 100 mg/L. The Sud-Chemie T-2525 catalyst was markedly better in the minimization of fines and particle carryover. It is anticipated the T-2525 can be installed as a direct replacement for the GAC in the peroxide decomposer columns. Based on the results of the peroxide method development work the recommendation is to purchase the T-2525 catalyst and initially load one of the ETF decomposer columns for full scale testing.

  1. The Use of Ion Chromatography for the Determination of Clean-In-Place-200 (CIP-200 Detergent Traces

    Directory of Open Access Journals (Sweden)

    Héctor Colón

    2006-01-01

    Full Text Available Anion chromatography with conductivity detection was chosen as the analytical technique for the development of a cleaning validation method for clean-in-place (CIP detergents. The method was developed and validated for the determination of traces of the detergent CIP-200. It was shown to be linear with a squared correlation coefficient (r2 of 0.9999 and the accuracy experiments presented average recoveries of 88.2% (area response factor from stainless steel surfaces. The repeatability was found to be 1.6% and an intermediate precision of 1.9% across the range. The method was also shown to be sensitive with an average Detection Limit (DL of 0.23 ppm and a Quantitation Limit (QL of 0.70 ppm based on the amount of phosphate in the detergent sample. The phosphate signal was well resolved from typical ions encountered in water samples or any other interference presented from swabs and surfaces. The method was applied to cleaning validation samples and proved to be suitable for rapid and reliable quality control.

  2. Calculo de tanque de PRFV de 200 000 litros de capacidad. // 200 000 liters capacity PRFV tank calculation.

    Directory of Open Access Journals (Sweden)

    J. García de la Figal Costales

    2002-01-01

    Full Text Available La tarea que se acomete es el cálculo a resistencia y rigidez de un tanque para el almacenamiento de agua, de 200 000 litrosde capacidad, construido de plástico reforzado con fibras de vidrio, PRFV. El mismo es cilíndrico vertical, de 8 metros dediámetro por 4.2 metros de altura. Los materiales seleccionados para la conformación de las láminas con las que se haránlos laminados de PRFV, fueron: resina poliéster isosftálica, y fibras de vidrio E.La carga fundamental a soportar por el tanque será la presión debida a la columna de agua en su interior, pero por estar a laintemperie y en zona de playa, se considerará también la acción de las dilataciones debidas a la temperatura, así como laacción de un ciclón.Palabras claves: resistencia, recipiente, composites, elementos finitos._____________________________________________________________________________Abstract.The stress and strains calculation of a water reinforced fiber glass container is carried out by means of a modern FiniteElement program, because the high complexity of calculus. The soported main load is the pressure caused by the column ofwater.Key words: Resistance, vessels, composites, finite elements.

  3. Preliminary engineering assessment of treatment alternatives for groundwater from the Hanford 200 Area 200-BP-5 plumes

    International Nuclear Information System (INIS)

    This report presents the results of the Preliminary Engineering Assessment of Treatment Alternatives (PEATA), an engineering evaluation of potential treatment alternatives for groundwater extracted from the 200-BP-5 Area's 216-BY Cribs and 216-B-5 Reverse Well plumes. The primary objective of the PEATA was to identify treatment technologies that are worth further consideration (i.e., treatability testing or a more refined engineering evaluation). It will also provide a basis for evaluating the results of the treatability testing that is currently being conducted on the presumptive remedy of ion exchange with disposal of spent resin and will serve as a guide for selection of other technologies for additional testing. Because there are little data or past experience with groundwater similar to the BY-Crib and B-5 Reverse Well Plumes, treatment efficiencies cannot be predicted with certainty and rigorous treatment system designs and costs cannot be developed. This applies to all alternatives, including the presumptive remedy of ion exchange. The approach for this study was to develop conceptual designs and approximate costs for the treatment technologies that were most likely to be effective on the BY-Crib and B-5 Reverse Well groundwater

  4. miR-200b mediates post-transcriptional repression of ZFHX1B

    DEFF Research Database (Denmark)

    Christoffersen, Nanna Rønbjerg; Silahtaroglu, Asli; Ørom, Ulf Lupo Andersson;

    2007-01-01

    of E-cadherin. We show that Zfhx1b and miR-200b are regionally coexpressed in the adult mouse brain and that miR-200b represses the expression of Zfhx1b via multiple sequence elements present in the 3'-untranslated region. Overexpression of miR-200b leads to repression of endogenous ZFHX1B......, and inhibition of miR-200b relieves the repression of ZFHX1B. In accordance with these findings, miR-200b regulates the activity of the E-cadherin promoter....

  5. Characterization of biofilm in 200W fluidized bed reactors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Michelle H. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Saurey, Sabrina D. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Lee, Brady D. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Parker, Kent E. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Eisenhauer, Emalee E. R. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Cordova, Elsa A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Golovich, Elizabeth C. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2014-09-29

    Contaminated groundwater beneath the 200 West Area at the Hanford Site in Southeast Washington is currently being treated using a pump and treat system to remove organics, inorganics, radionuclides, and metals. A granular activated carbon-based fluidized bed reactor (FBR) has been added to remove nitrate, hexavalent chromium and carbon tetrachloride. Initial analytical results indicated the microorganisms effectively reduced many of the contaminants to less than cleanup levels. However shortly thereafter operational upsets of the FBR include carbon carry over, over production of microbial extracellular polymeric substance (biofilm) materials, and over production of hydrogen sulfide. As a result detailed investigations were undertaken to understand the functional diversity and activity of the microbial community present in the FBR over time. Molecular analyses including terminal restriction fragment length polymorphism analysis, quantitative polymerase chain reaction and fluorescent in situ hybridization analyses were performed on the microbial community extracted from the biofilm within the bed and from the inoculum, to determine functional dynamics of the FBR bed over time and following operational changes. Findings from these analyses indicated: 1) the microbial community within the bed was completely different than community used for inoculation, and was likely from the groundwater; 2) analyses early in the testing showed an FBR community dominated by a few Curvibacter and Flavobacterium species; 3) the final sample taken indicated that the microbial community in the FBR bed had become more diverse; and 4) qPCR analyses indicated that bacteria involved in nitrogen cycling, including denitrifiers and anaerobic ammonia oxidizing bacteria, were dominant in the bed. These results indicate that molecular tools can be powerful for determining functional diversity within FBR type reactors. Coupled with micronutrient, influent and effluent chemistry

  6. Characterization of Biofilm in 200W Fluidized Bed Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Michelle H.; Saurey, Sabrina D.; Lee, Brady D.; Parker, Kent E.; Eisenhauer, Emalee ER; Cordova, Elsa A.; Golovich, Elizabeth C.

    2014-09-29

    Contaminated groundwater beneath the 200 West Area at the Hanford Site in Southeast Washington is currently being treated using a pump and treat system to remove organics, inorganics, radionuclides, and metals. A granular activated carbon-based fluidized bed reactor (FBR) has been added to remove nitrate, hexavalent chromium and carbon tetrachloride. Initial analytical results indicated the microorganisms effectively reduced many of the contaminants to less than cleanup levels. However shortly thereafter operational upsets of the FBR include carbon carry over, over production of microbial extracellular polymeric substance (biofilm) materials, and over production of hydrogen sulfide. As a result detailed investigations were undertaken to understand the functional diversity and activity of the microbial community present in the FBR over time. Molecular analyses including terminal restriction fragment length polymorphism analysis, quantitative polymerase chain reaction and fluorescent in situ hybridization analyses were performed on the microbial community extracted from the biofilm within the bed and from the inoculum, to determine functional dynamics of the FBR bed over time and following operational changes. Findings from these analyses indicated: 1) the microbial community within the bed was completely different than community used for inoculation, and was likely from the groundwater; 2) analyses early in the testing showed an FBR community dominated by a few Curvibacter and Flavobacterium species; 3) the final sample taken indicated that the microbial community in the FBR bed had become more diverse; and 4) qPCR analyses indicated that bacteria involved in nitrogen cycling, including denitrifiers and anaerobic ammonia oxidizing bacteria, were dominant in the bed. These results indicate that molecular tools can be powerful for determining functional diversity within FBR type reactors. Coupled with micronutrient, influent and effluent chemistry evaluations, a more

  7. CEBAF 200 kV Inverted Electron Gun

    Energy Technology Data Exchange (ETDEWEB)

    Grames, J M; Clark, J; Hansknecht, J; Poelker, M; Stutzman, M L; Suleiman, R; Surles-Law, K.E.L.; BastaniNejad, M

    2011-03-01

    Two DC high volt­age GaAs pho­to­guns have been built at Jef­fer­son Lab based on a com­pact in­vert­ed in­su­la­tor de­sign. One pho­to­gun pro­vides the po­lar­ized elec­tron beam at CEBAF and op­er­ates at 130 kV bias volt­age. The other gun is used for high av­er­age cur­rent life­time stud­ies at a ded­i­cat­ed test fa­cil­i­ty and has been op­er­at­ed at bias volt­age up to 225 kV. The ad­van­tages of high­er DC volt­age for CEBAF in­clude re­duced space-charge emit­tance growth and the po­ten­tial for pro­longed pho­to­cath­ode life­time. How­ev­er, a con­se­quence of op­er­at­ing at high­er volt­ages is the in­creased like­li­hood of field emis­sion or break­down, both of which are un­ac­cept­able. High­lights of the R&D stud­ies lead­ing to­ward a pro­duc­tion 200keV GaAs pho­to­gun for CEBAF will be pre­sent­ed.

  8. miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus

    Institute of Scientific and Technical Information of China (English)

    Cameron M Smith; David I Watson; Mary P Leong; George C Mayne; Michael Z Michael; Bas PL Wijnhoven; Damian J Hussey

    2011-01-01

    AIM:To investigate miR-200 family expression in Barrett's epithelium,gastric and duodenal epithelia,and esophageal adenocarcinoma. METHODS:Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200,ZEB1 and ZEB2 expression.Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS:Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001).In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenal epithelia,and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02),and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02).The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium.We observed significant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION:miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.

  9. Pulsar polarisation below 200 MHz: Average profiles and propagation effects

    Science.gov (United States)

    Noutsos, A.; Sobey, C.; Kondratiev, V. I.; Weltevrede, P.; Verbiest, J. P. W.; Karastergiou, A.; Kramer, M.; Kuniyoshi, M.; Alexov, A.; Breton, R. P.; Bilous, A. V.; Cooper, S.; Falcke, H.; Grießmeier, J.-M.; Hassall, T. E.; Hessels, J. W. T.; Keane, E. F.; Osłowski, S.; Pilia, M.; Serylak, M.; Stappers, B. W.; ter Veen, S.; van Leeuwen, J.; Zagkouris, K.; Anderson, K.; Bähren, L.; Bell, M.; Broderick, J.; Carbone, D.; Cendes, Y.; Coenen, T.; Corbel, S.; Eislöffel, J.; Fender, R.; Garsden, H.; Jonker, P.; Law, C.; Markoff, S.; Masters, J.; Miller-Jones, J.; Molenaar, G.; Osten, R.; Pietka, M.; Rol, E.; Rowlinson, A.; Scheers, B.; Spreeuw, H.; Staley, T.; Stewart, A.; Swinbank, J.; Wijers, R.; Wijnands, R.; Wise, M.; Zarka, P.; van der Horst, A.

    2015-04-01

    Aims: We present the highest-quality polarisation profiles to date of 16 non-recycled pulsars and four millisecond pulsars, observed below 200 MHz with the LOFAR high-band antennas. Based on the observed profiles, we perform an initial investigation of expected observational effects resulting from the propagation of polarised emission in the pulsar magnetosphere and the interstellar medium. Methods: The polarisation data presented in this paper have been calibrated for the geometric-projection and beam-shape effects that distort the polarised information as detected with the LOFAR antennas. We have used RM Synthesis to determine the amount of Faraday rotation in the data at the time of the observations. The ionospheric contribution to the measured Faraday rotation was estimated using a model of the ionosphere. To study the propagation effects, we have compared our low-frequency polarisation observations with archival data at 240, 400, 600, and 1400 MHz. Results: The predictions of magnetospheric birefringence in pulsars have been tested using spectra of the pulse width and fractional polarisation from multifrequency data. The derived spectra offer only partial support for the expected effects of birefringence on the polarisation properties, with only about half of our sample being consistent with the model's predictions. It is noted that for some pulsars these measurements are contaminated by the effects of interstellar scattering. For a number of pulsars in our sample, we have observed significant variations in the amount of Faraday rotation as a function of pulse phase, which is possibly an artefact of scattering. These variations are typically two orders of magnitude smaller than that observed at 1400 MHz by Noutsos et al. (2009), for a different sample of southern pulsars. In this paper we present a possible explanation for the difference in magnitude of this effect between the two frequencies, based on scattering. Finally, we have estimated the magnetospheric

  10. Aerial Photography and Imagery, Ortho-Corrected, 2008 Orthoimagery 200 Scale, Published in 2008, 1:2400 (1in=200ft) scale, Caldwell County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Aerial Photography and Imagery, Ortho-Corrected dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of...

  11. Roles of methionine oxidation in E200K prion protein misfolding: Implications for the mechanism of pathogenesis in E200K linked familial Creutzfeldt-Jakob disease.

    Science.gov (United States)

    Wang, Zonglin; Feng, Boya; Xiao, Gengfu; Zhou, Zheng

    2016-04-01

    Prion diseases are a group of neurodegenerative diseases caused by prion protein (PrP) conformational changes. More than 30 PRNP gene mutations have been associated with familial prion diseases. E200K-associated familial Creutzfeldt-Jakob disease (fCJD) is the most common inherited prion disease. One of the hallmarks of prion diseases is the accumulation of oxidative damage. The mechanism by which oxidative modification of methionine (Met) residues influence the E200K PrP misfolding remains unclear. Here, we examined the stability, structural change, oligomerization and proteinase K resistance of unoxidized/oxidized E200K PrP and Met-to-Leu mutants. We found that oxidation of surface-exposed Met109/112/129/134/154/166 residues significantly destabilized E200K PrP but had a limited impact on the protein's structure. The oxidation of Met213 was the initial step in the conformational conversion of E200K PrP and facilitated the further oxidation of Met205/206. The oxidation of Met213/205/206 led to the exposure of the inner hydrophobic core, disrupted the overall structure of E200K PrP and induced the formation of large soluble multimers at low pH. In addition, the aggregation behavior of oxidized E200K PrP at the cellular level was investigated using E200K PrP Met-to-Ser mutants. The results showed that M109/112/129/154S or M134/166S mutants were efficiently localized on the cell membrane, whereas the M213/205/206S mutant generated many of aggregated fluorescent dots in the cytoplasm. The present work provides important clues for understanding the special roles of methionine oxidation in E200K PrP misfolding and links oxidative stress and consequent misfolding of oxidative damaged E200K PrP with the pathogenic mechanism of E200K-associated fCJD.

  12. Roles of methionine oxidation in E200K prion protein misfolding: Implications for the mechanism of pathogenesis in E200K linked familial Creutzfeldt-Jakob disease.

    Science.gov (United States)

    Wang, Zonglin; Feng, Boya; Xiao, Gengfu; Zhou, Zheng

    2016-04-01

    Prion diseases are a group of neurodegenerative diseases caused by prion protein (PrP) conformational changes. More than 30 PRNP gene mutations have been associated with familial prion diseases. E200K-associated familial Creutzfeldt-Jakob disease (fCJD) is the most common inherited prion disease. One of the hallmarks of prion diseases is the accumulation of oxidative damage. The mechanism by which oxidative modification of methionine (Met) residues influence the E200K PrP misfolding remains unclear. Here, we examined the stability, structural change, oligomerization and proteinase K resistance of unoxidized/oxidized E200K PrP and Met-to-Leu mutants. We found that oxidation of surface-exposed Met109/112/129/134/154/166 residues significantly destabilized E200K PrP but had a limited impact on the protein's structure. The oxidation of Met213 was the initial step in the conformational conversion of E200K PrP and facilitated the further oxidation of Met205/206. The oxidation of Met213/205/206 led to the exposure of the inner hydrophobic core, disrupted the overall structure of E200K PrP and induced the formation of large soluble multimers at low pH. In addition, the aggregation behavior of oxidized E200K PrP at the cellular level was investigated using E200K PrP Met-to-Ser mutants. The results showed that M109/112/129/154S or M134/166S mutants were efficiently localized on the cell membrane, whereas the M213/205/206S mutant generated many of aggregated fluorescent dots in the cytoplasm. The present work provides important clues for understanding the special roles of methionine oxidation in E200K PrP misfolding and links oxidative stress and consequent misfolding of oxidative damaged E200K PrP with the pathogenic mechanism of E200K-associated fCJD. PMID:26779934

  13. Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system.

    Science.gov (United States)

    Hernangómez, Miriam; Carrillo-Salinas, Francisco J; Mecha, Miriam; Correa, Fernando; Mestre, Leyre; Loría, Frida; Feliú, Ana; Docagne, Fabian; Guaza, Carmen

    2014-01-01

    The central nervous system (CNS) innate immune response includes an arsenal of molecules and receptors expressed by professional phagocytes, glial cells and neurons that is involved in host defence and clearance of toxic and dangerous cell debris. However, any uncontrolled innate immune responses within the CNS are widely recognized as playing a major role in the development of autoimmune disorders and neurodegeneration, with multiple sclerosis (MS) Alzheimer's disease (AD) being primary examples. Hence, it is important to identify the key regulatory mechanisms involved in the control of CNS innate immunity and which could be harnessed to explore novel therapeutic avenues. Neuroimmune regulatory proteins (NIReg) such as CD95L, CD200, CD47, sialic acid, complement regulatory proteins (CD55, CD46, fH, C3a), HMGB1, may control the adverse immune responses in health and diseases. In the absence of these regulators, when neurons die by apoptosis, become infected or damaged, microglia and infiltrating immune cells are free to cause injury as well as an adverse inflammatory response in acute and chronic settings. We will herein provide new emphasis on the role of the pair CD200-CD200R in MS and its experimental models: experimental autoimmune encephalomyelitis (EAE) and Theiler's virus induced demyelinating disease (TMEV-IDD). The interest of the cannabinoid system as inhibitor of inflammation prompt us to introduce our findings about the role of endocannabinoids (eCBs) in promoting CD200-CD200 receptor (CD200R) interaction and the benefits caused in TMEV-IDD. Finally, we also review the current data on CD200-CD200R interaction in AD, as well as, in the aging brain. PMID:24588829

  14. Tumor-derived vaccines containing CD200 inhibit immune activation: implications for immunotherapy.

    Science.gov (United States)

    Xiong, Zhengming; Ampudia-Mesias, Elisabet; Shaver, Rob; Horbinski, Craig M; Moertel, Christopher L; Olin, Michael R

    2016-09-01

    There are over 400 ongoing clinical trials using tumor-derived vaccines. This approach is especially attractive for many types of brain tumors, including glioblastoma, yet so far the clinical response is highly variable. One contributor to poor response is CD200, which acts as a checkpoint blockade, inducing immune tolerance. We demonstrate that, in response to vaccination, glioma-derived CD200 suppresses the anti-tumor immune response. In contrast, a CD200 peptide inhibitor that activates antigen-presenting cells overcomes immune tolerance. The addition of the CD200 inhibitor significantly increased leukocyte infiltration into the vaccine site, cytokine and chemokine production, and cytolytic activity. Our data therefore suggest that CD200 suppresses the immune system's response to vaccines, and that blocking CD200 could improve the efficacy of cancer immunotherapy. PMID:27485078

  15. SRP engineering and design history, Vol III, 200 F and H Areas

    Energy Technology Data Exchange (ETDEWEB)

    Banick, C.J.

    2000-04-17

    This volume combines the record of events relating to the development of design for both the 200-F and H Areas. Chronologically, the definition of plant facilities was first established for the 200-F Area. The second area, 200-H, was projected initially to be a supplementary plutonium separations facility. This history explains the differences in character and capacity of the manufacturing facilities in both areas as production requirements and experience with separations processes advanced.

  16. SRP engineering and design history, Vol III, 200 F and H Areas

    International Nuclear Information System (INIS)

    This volume combines the record of events relating to the development of design for both the 200-F and H Areas. Chronologically, the definition of plant facilities was first established for the 200-F Area. The second area, 200-H, was projected initially to be a supplementary plutonium separations facility. This history explains the differences in character and capacity of the manufacturing facilities in both areas as production requirements and experience with separations processes advanced

  17. 17 CFR 200.30-1 - Delegation of authority to Director of Division of Corporation Finance.

    Science.gov (United States)

    2010-04-01

    ... 304(d) of the Act (15 U.S.C. 77ddd(d)) and rule 4d-7 thereunder (17 CFR 260.4d-7 of this chapter). (5...). Editorial Note: For Federal Register citations affecting § 200.30-1 see the List of CFR Sections Affected... Director of Division of Corporation Finance. 200.30-1 Section 200.30-1 Commodity and Securities...

  18. Comparison of the Nellcor N-200 and N-3000 pulse oximeters during simulated postoperative activities

    DEFF Research Database (Denmark)

    Lie, C; Kehlet, H; Rosenberg, J

    1997-01-01

    Twenty-six healthy volunteers were monitored simultaneously with the Nellcor N-200 and N-3000 pulse oximeters during nonhypoxaemic simulated postoperative activity. The overall number of registered events (hypoxaemic episodes or loss of signal) was fewer with the N-3000 than with the N-200 (8 vs...... to loss of signal were significantly rarer with the N-3000 than with the N-200 (3 vs. 13, p = 0.001). The Nellcor N-3000 oximeter may offer an advantage over the N-200 model when monitoring patients in the postoperative period....

  19. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

    Directory of Open Access Journals (Sweden)

    Yuan Liu

    2015-01-01

    Full Text Available Purpose. The small nuclear ribonucleoprotein 200 kDa (SNRNP200 gene is a fundamental component for precursor message RNA (pre-mRNA splicing and has been implicated in the etiology of autosomal dominant retinitis pigmentosa (adRP. This study aims to determine the consequences of knocking down Snrnp200 in zebrafish. Methods. Expression of the Snrnp200 transcript in zebrafish was determined via whole mount in situ hybridization. Morpholino oligonucleotide (MO aiming to knock down the expression of Snrnp200 was injected into zebrafish embryos, followed by analyses of aberrant splicing and expression of the U4/U6-U5 tri-small nuclear ribonucleoproteins (snRNPs components and retina-specific transcripts. Systemic changes and retinal phenotypes were further characterized by histological study and immunofluorescence staining. Results. Snrnp200 was ubiquitously expressed in zebrafish. Knocking down Snrnp200 in zebrafish triggered aberrant splicing of the cbln1 gene, upregulation of other U4/U6-U5 tri-snRNP components, and downregulation of a panel of retina-specific transcripts. Systemic defects were found correlated with knockdown of Snrnp200 in zebrafish. Only demorphogenesis of rod photoreceptors was detected in the initial stage, mimicking the disease characteristics of RP. Conclusions. We conclude that knocking down Snrnp200 in zebrafish could alter regular splicing and expression of a panel of genes, which may eventually trigger rod defects.

  20. Solubility of Naproxen in Polyethylene Glycol 200 + Water Mixtures at Various Temperatures

    OpenAIRE

    Panahi-Azar, Vahid; Soltanpour, Shahla; Martinez, Fleming; Jouyban, Abolghasem

    2015-01-01

    The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree model with van’t Hoff equation can be used to predict solubility in PEG 200 + water with only four so...

  1. A Truncated form of CD200 (CD200S) Expressed on Glioma Cells Prolonged Survival in a Rat Glioma Model by Induction of a Dendritic Cell-Like Phenotype in Tumor-Associated Macrophages12

    Science.gov (United States)

    Kobayashi, Kana; Yano, Hajime; Umakoshi, Akihiro; Matsumoto, Shirabe; Mise, Ayano; Funahashi, Yu; Ueno, Yoshitomo; Kamei, Yoshiaki; Takada, Yasutsugu; Kumon, Yoshiaki; Ohnishi, Takanori; Tanaka, Junya

    2016-01-01

    CD200 induces immunosuppression in myeloid cells expressing its receptor CD200R, which may have consequences for tumor immunity. We found that human carcinoma tissues express not only full-length CD200 (CD200L) but also its truncated form, CD200S. Although CD200S is reported to antagonize the immunosuppressive actions of CD200L, the role of CD200S in tumor immunity has never been investigated. We established rat C6 glioma cell lines that expressed either CD200L or CD200S; the original C6 cell line did not express CD200 molecules. The cell lines showed no significant differences in growth. Upon transplantation into the neonatal Wistar rat forebrain parenchyma, rats transplanted with C6-CD200S cells survived for a significantly longer period than those transplanted with the original C6 and C6-CD200L cells. The C6-CD200S tumors were smaller than the C6-CD200L or C6-original tumors, and many apoptotic cells were found in the tumor cell aggregates. Tumor-associated macrophages (TAMs) in C6-CD200S tumors displayed dendritic cell (DC)-like morphology with multiple processes and CD86 expression. Furthermore, CD3+, CD4+ or CD8+ cells were more frequently found in C6-CD200S tumors, and the expression of DC markers, granzyme, and perforin was increased in C6-CD200S tumors. Isolated TAMs from original C6 tumors were co-cultured with C6-CD200S cells and showed increased expression of DC markers. These results suggest that CD200S activates TAMs to become DC-like antigen presenting cells, leading to the activation of CD8+ cytotoxic T lymphocytes, which induce apoptotic elimination of tumor cells. The findings on CD200S action may provide a novel therapeutic modality for the treatment of carcinomas. PMID:27108386

  2. A Truncated form of CD200 (CD200S Expressed on Glioma Cells Prolonged Survival in a Rat Glioma Model by Induction of a Dendritic Cell-Like Phenotype in Tumor-Associated Macrophages

    Directory of Open Access Journals (Sweden)

    Kana Kobayashi

    2016-04-01

    Full Text Available CD200 induces immunosuppression in myeloid cells expressing its receptor CD200R, which may have consequences for tumor immunity. We found that human carcinoma tissues express not only full-length CD200 (CD200L but also its truncated form, CD200S. Although CD200S is reported to antagonize the immunosuppressive actions of CD200L, the role of CD200S in tumor immunity has never been investigated. We established rat C6 glioma cell lines that expressed either CD200L or CD200S; the original C6 cell line did not express CD200 molecules. The cell lines showed no significant differences in growth. Upon transplantation into the neonatal Wistar rat forebrain parenchyma, rats transplanted with C6-CD200S cells survived for a significantly longer period than those transplanted with the original C6 and C6-CD200L cells. The C6-CD200S tumors were smaller than the C6-CD200L or C6-original tumors, and many apoptotic cells were found in the tumor cell aggregates. Tumor-associated macrophages (TAMs in C6-CD200S tumors displayed dendritic cell (DC-like morphology with multiple processes and CD86 expression. Furthermore, CD3+, CD4+ or CD8+ cells were more frequently found in C6-CD200S tumors, and the expression of DC markers, granzyme, and perforin was increased in C6-CD200S tumors. Isolated TAMs from original C6 tumors were co-cultured with C6-CD200S cells and showed increased expression of DC markers. These results suggest that CD200S activates TAMs to become DC-like antigen presenting cells, leading to the activation of CD8+ cytotoxic T lymphocytes, which induce apoptotic elimination of tumor cells. The findings on CD200S action may provide a novel therapeutic modality for the treatment of carcinomas.

  3. 34 CFR 200.89 - MEP allocations; Re-interviewing; Eligibility documentation; and Quality control.

    Science.gov (United States)

    2010-07-01

    ... determining eligibility and in conducting quality control procedures know the requirements for accurately... documentation; and Quality control. 200.89 Section 200.89 Education Regulations of the Offices of the Department...-interviewing; Eligibility documentation; and Quality control. (a) Allocation of funds under the MEP for...

  4. 29 CFR 2530.200b-7 - Day of service for employees in the maritime industry.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Day of service for employees in the maritime industry. 2530.200b-7 Section 2530.200b-7 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY... industry. (a) General rule. A day of service in the maritime industry which must, as a minimum, be...

  5. MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors.

    Directory of Open Access Journals (Sweden)

    Mikael Lerner

    Full Text Available The pro-apoptotic p53 target Noxa is a BH3-only protein that antagonizes the function of selected anti-apoptotic Bcl-2 family members. While much is known regarding the transcriptional regulation of Noxa, its posttranscriptional regulation remains relatively unstudied. In this study, we therefore investigated whether Noxa is regulated by microRNAs. Using a screen combining luciferase reporters, bioinformatic target prediction analysis and microRNA expression profiling, we identified miR-200c as a negative regulator of Noxa expression. MiR-200c was shown to repress basal expression of Noxa, as well as Noxa expression induced by various stimuli, including proteasomal inhibition. Luciferase reporter experiments furthermore defined one miR-200c target site in the Noxa 3'UTR that is essential for this direct regulation. In spite of the miR-200c:Noxa interaction, miR-200c overexpression led to increased sensitivity to the clinically used proteasomal inhibitor bortezomib in several cell lines. This apparently contradictory finding was reconciled by the fact that in cells devoid of Noxa expression, miR-200c overexpression had an even more pronounced positive effect on apoptosis induced by proteasomal inhibition. Together, our data define miR-200c as a potentiator of bortezomib-induced cell death. At the same time, we show that miR-200c is a novel negative regulator of the pro-apoptotic Bcl-2 family member Noxa.

  6. 21 CFR 201.200 - Disclosure of drug efficacy study evaluations in labeling and advertising.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Disclosure of drug efficacy study evaluations in labeling and advertising. 201.200 Section 201.200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... Commissioner of Food and Drugs from the National Academy of Sciences (1969).” As the report notes, this...

  7. 40 CFR 270.200 - How may I renew my RAP if it is expiring?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false How may I renew my RAP if it is expiring? 270.200 Section 270.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... renew my RAP if it is expiring? If you wish to renew your expiring RAP, you must follow the process...

  8. 24 CFR 200.947 - Building product standards and certification program for polystyrene foam insulation board.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Building product standards and certification program for polystyrene foam insulation board. 200.947 Section 200.947 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING...

  9. 76 FR 38062 - Airworthiness Directives; Gulfstream Aerospace LP Model Galaxy and Gulfstream 200 Airplanes

    Science.gov (United States)

    2011-06-29

    ... 12866; 2. Is not a ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034... Aerospace LP Model Galaxy and Gulfstream 200 Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... LP Model Galaxy and Gulfstream 200 airplanes, certificated in any category, serial numbers...

  10. 24 CFR 200.950 - Building product standards and certification program for solar water heating system.

    Science.gov (United States)

    2010-04-01

    ... certification program for solar water heating system. 200.950 Section 200.950 Housing and Urban Development... solar water heating system. (a) Applicable standards. (1) All solar water heating systems shall be...) Document OG-300-93, Operating Guidelines and Minimum Standards for Certifying Solar Water Heating...

  11. 30 CFR 243.200 - How do I demonstrate financial solvency?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I demonstrate financial solvency? 243.200 Section 243.200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT SUSPENSIONS PENDING APPEAL AND BONDING-MINERALS REVENUE MANAGEMENT Financial...

  12. 28 CFR 200.1 - Eligibility for Protection under the Convention Against Torture.

    Science.gov (United States)

    2010-07-01

    ... Convention Against Torture. 200.1 Section 200.1 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... Torture. A removal order under Title V of the Act shall not be executed in circumstances that would violate Article 3 of the United Nations Convention Against Torture and Other Cruel, Inhuman or...

  13. 34 CFR 200.66 - Requirements to ensure that funds do not benefit a private school.

    Science.gov (United States)

    2010-07-01

    ... private school. 200.66 Section 200.66 Education Regulations of the Offices of the Department of Education... private school. (a) An LEA must use funds under subpart A of this part to provide services that supplement, and in no case supplant, the services that would, in the absence of Title I services, be available...

  14. 49 CFR 179.200-23 - Tests of pressure relief valves.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Tests of pressure relief valves. 179.200-23 Section 179.200-23 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS...-23 Tests of pressure relief valves. (a) Each valve shall be tested by air or gas for compliance...

  15. 7 CFR 25.200 - Nominations by State and local governments.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Nominations by State and local governments. 25.200... COMMUNITIES Nomination Procedure § 25.200 Nominations by State and local governments. (a) Nomination criteria. One or more local governments and the States in which an area is located must nominate such area...

  16. 19 CFR 200.735-114 - Employees required to submit statements.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Employees required to submit statements. 200.735... Employees required to submit statements. Except as provided in § 200.735-114a, the following employees shall submit confidential statements of employment and financial interests: (a)(1) Employees in grade GS-13...

  17. 24 CFR 200.77 - Lead-based paint poisoning prevention.

    Science.gov (United States)

    2010-04-01

    ...-based paint poisoning prevention. Requirements set forth in 24 CFR part 35 apply to these programs. ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Lead-based paint poisoning prevention. 200.77 Section 200.77 Housing and Urban Development Regulations Relating to Housing and...

  18. 34 CFR 200.47 - SEA responsibilities for supplemental educational services.

    Science.gov (United States)

    2010-07-01

    ... appropriate supplemental educational services and language assistance in the provision of those services. (b... sound; and (iv) In the case of— (A) A public school, has not been identified under §§ 200.32, 200.33, or... format, including alternative formats upon request, and, to the extent practicable, in a language...

  19. 13 CFR 123.200 - Am I eligible to apply for a physical disaster business loan?

    Science.gov (United States)

    2010-01-01

    ..., corporation, limited liability company, or other legal entity recognized under State law. Your business' size... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Am I eligible to apply for a physical disaster business loan? 123.200 Section 123.200 Business Credit and Assistance SMALL...

  20. 20 CFR 663.200 - What are intensive services for adults and dislocated workers?

    Science.gov (United States)

    2010-04-01

    ... dislocated workers? 663.200 Section 663.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION... services are listed in WIA section 134(d)(3)(C). The list in the Act is not all-inclusive and other... assessment or individual employment plan. (b) For the purposes of paragraph (a) of this section,...

  1. 20 CFR 666.200 - Under what circumstances is a State eligible for an Incentive Grant?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Under what circumstances is a State eligible for an Incentive Grant? 666.200 Section 666.200 Employees' Benefits EMPLOYMENT AND TRAINING... satisfaction indicators for WIA title I programs; (b) The adjusted levels of performance for title II...

  2. 24 CFR 200.936 - Supplementary specific procedural requirements under HUD building products certification program...

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Supplementary specific procedural requirements under HUD building products certification program for solid fuel type room heaters and fireplace stoves. 200.936 Section 200.936 Housing and Urban Development Regulations Relating to Housing and...

  3. 34 CFR 200.80 - Migrant Education Even Start Program definition.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Migrant Education Even Start Program definition. 200.80... DISADVANTAGED Even Start Family Literacy Program § 200.80 Migrant Education Even Start Program definition. Eligible participants under the Migrant Education Even Start Program (MEES) must meet the definitions of...

  4. Development of a 200kW multi-fuel type PAFC power plant

    Energy Technology Data Exchange (ETDEWEB)

    Take, Tetsuo; Kuwata, Yutaka; Adachi, Masahito; Ogata, Tsutomu [NTT Integrated Information & Energy System Labs., Tokyo (Japan)

    1996-12-31

    Nippon Telegraph and Telephone Corporation (NFT) has been developing a 200 kW multi-fuel type PAFC power plant which can generate AC 200 kW of constant power by switching fuel from pipeline town gas to liquefied propane gas (LPG) and vice versa. This paper describes the outline of the demonstration test plant and test results of its fundamental characteristics.

  5. 24 CFR 200.194 - Placement of nonprofit organization on Nonprofit Organization Roster.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Placement of nonprofit organization on Nonprofit Organization Roster. 200.194 Section 200.194 Housing and Urban Development Regulations... Placement and Removal Procedures for Participation in FHA Programs Nonprofit Organization §...

  6. 24 CFR 200.195 - Removal of nonprofit organization from Nonprofit Organization Roster.

    Science.gov (United States)

    2010-04-01

    ... prohibits HUD from taking such other action against a nonprofit organization, as provided in 2 CFR part 2424... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Removal of nonprofit organization from Nonprofit Organization Roster. 200.195 Section 200.195 Housing and Urban Development...

  7. Changes of serum levels of miR-200b and miR-200c in patients with gastric cancer and its clinical significance%胃癌患者血清miR-200b和miR-200c水平变化及临床意义

    Institute of Scientific and Technical Information of China (English)

    陈志凯; 傅松维; 鲍舟君; 李卓栋

    2016-01-01

    目的 观察胃癌患者血清miR-200b和miR-200c水平变化特点,探讨其临床意义.方法 回顾性分析浙江省舟山医院自2012年1月~2014年6月消化内科及胃肠外科收治的84例胃癌患者为研究对象(观察组),选择30例健康人为对照组.采用qRT-PCR检测所有研究对象血清miR-200b和miR-200c水平,比较2组间血清miR-200b和miR-200c水平差异,探讨胃癌患者血清miR-200b和miR-200c水平与其临床及病理特点之间的关系.结果 胃癌组血清miR-200b和miR-200c水平均明显低于对照组,差异均有统计学意义(均P <0.05).胃癌患者不同年龄、性别、分化程度和浸润深度之间血清miR-200b和miR-200c水平差异无统计学意义;较高临床分期及合并淋巴结转移的患者血清miR-200b和miR-200c水平明显低于较低临床分期和无淋巴结转移者,差异均有统计学意义(均P <0.05).血清miR-200b和miR-200c水平诊断胃癌的AUC分别为0.826(95% CI:0.741 ~ 0.911,P<0.001)和0.856(95%CI:0.778 ~0.935,P<0.001).结论 胃癌患者血清miR-200b和miR-200c水平明显降低,并且与临床分期和淋巴结转移密切相关,检测血清miR-200b和miR-200c水平有助于判断胃癌并判断预后.

  8. Structural Features and In-service Inspection of the LTNHR-200 Pressure Vessel

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The pressure vessel of 200 MW low temperature nuclear heating reactor (LTNHR-200) is the main part of primary pressure boundary and its reasonable and reliable structural design is the key point to assure the safe operation of LTNHR-200. The double-shell pressure vessels were designed. LTNHR-200 pressure vessel meets the condition of Leak Before Break and has a relatively low failure probability. Metal containment (outer pressure vessel) has the similar features to LTNHR-200 pressure vessel. There exists no LOCA and core melting with the double vessel. The in-service inspection of the pressure vessel can be simplified greatly because of the safety and structural features of the reactor.

  9. Fiscal Year 1997 Annual Report for the 100-NR-2, 200-UP-1, and 200-ZP-1 Pump and Treat Operations and Operable Units

    International Nuclear Information System (INIS)

    The Environmental Restoration Contractor (ERC), Bechtel Hanford, Inc., conducts groundwater remediation activities across the Hanford Site for the U.S. Department of Energy. Operable units, as defined under CERCLA, have been established to address groundwater contamination issues in various areas of the Site. Groundwater within these operable units has been contaminated by a variety of chemical and radiological constituents associated with past-practices liquid effluent disposal, as well as accidental leaks and spills. The ERC is currently operating three pump-and-treat systems in the 100 Area: Strontium-90 is being addressed in the 100-NR-2 Operable Unit, while hexavalent chromium is being addressed in the 100-KR-4 and 100-HR-3 Operable Units. In the 200 Area, technetium-99, uranium, carbon tetrachloride, and nitrate are being addressed in the 200-UP-1 Operable Unit, while carbon tetrachloride, trichloroethene, and chloroform are being addressed in the 200-ZP-1 Operable Unit

  10. Study on Training of 200m Running during Junior Middle School%对初中200米跑训练的研究

    Institute of Scientific and Technical Information of China (English)

    陈俊达

    2012-01-01

    目的:探讨初中200米跑切实有效的训练方法,提高初三学生中考体育加试成绩。方法:采取不同的训练方法进行对照实验的研究方法,对所得结果进行数理统计与分析。结果:实验组采取综合训练方法,200米跑成绩比对照组有显著性提高(P〈0.05)。结论:采取科学的训练方法,并合理地安排训练内容,可以大幅度提高初中200米跑成绩。建议:采取本文的训练方法,将全面提高初中生中考体育加试成绩。%Objective: To explore the 200m running effective training methods of junior middle school, improve grade students in senior high school entrance examination of physical tests. Methods : different training methods for controlled experiments, the results of statistics and analysis are made. Results: the experimental group take comprehensive training method, 200m race result had significantly increased than the control group ( P 〈 0.05 ). Conclusion: the use of scientific training methods, and reasonable arrangements for the training content, can greatly improve the junior middle school 200m race result. Suggestion: Taking the training methods in this paper will improve the junior middle school students in senior high school entrance examination of physical tests.

  11. Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer

    DEFF Research Database (Denmark)

    Wiklund, Erik D; Bramsen, Jesper B; Hulf, Toby;

    2011-01-01

    MicroRNAs (miRNA) are small noncoding RNAs commonly deregulated in cancer. The miR-200 family (miR-200a, -200b, -200c, -141 and -429) and miR-205 are frequently silenced in advanced cancer and have been implicated in epithelial to mesenchymal transition (EMT) and tumor invasion by targeting the t...

  12. Melanoma Cell Expression of CD200 Inhibits Tumor Formation and Lung Metastasis via Inhibition of Myeloid Cell Functions

    OpenAIRE

    Talebian, Fatemeh; Liu, Jin-Qing; Liu, Zhenzhen; Khattabi, Mazin; He, Yukai; Ganju, Ramesh; Bai, Xue-feng

    2012-01-01

    CD200 is a cell surface glycoprotein that functions through engaging CD200 receptor on cells of the myeloid lineage and inhibits their functions. Expression of CD200 has been implicated in a variety of human cancer cells including melanoma cells and has been thought to play a protumor role. To investigate the role of cancer cell expression of CD200 in tumor formation and metastasis, we generated CD200-positive and CD200-negative B16 melanoma cells. Subcutaneous injection of CD200-positive B16...

  13. Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice

    Science.gov (United States)

    Yin, Yufeng; Zhao, Lidan; Zhang, Fengchun; Zhang, Xuan

    2016-01-01

    Abnormal expression of CD200/CD200R1 may contribute to the immunologic abnormalities in patients with systemic lupus erythematosus (SLE). This study aimed to assess the function of CD200/CD200R1and impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. Female NZB/WF1 mice were treated with CD200-Fc or control for 4 weeks. Plasma samples were collected to measure autoantibody levels. The expression levels of CD200/CD200R1 in peripheral blood mononuclear cells (PBMCs) and splenocytes were examined. The percentage of CD200/CD200R1-positive cells in splenocytes from NZB/WF1 mice was lower than that of C57BL/6 mice (p lupus. PMID:27545083

  14. BAF200 is required for heart morphogenesis and coronary artery development.

    Directory of Open Access Journals (Sweden)

    Lingjuan He

    Full Text Available ATP-dependent SWI/SNF chromatin remodeling complexes utilize ATP hydrolysis to non-covalently change nucleosome-DNA interactions and are essential in stem cell development, organogenesis, and tumorigenesis. Biochemical studies show that SWI/SNF in mammalian cells can be divided into two subcomplexes BAF and PBAF based on the subunit composition. ARID2 or BAF200 has been defined as an intrinsic subunit of PBAF complex. However, the function of BAF200 in vivo is not clear. To dissect the possible role of BAF200 in regulating embryogenesis and organ development, we generated BAF200 mutant mice and found they were embryonic lethal. BAF200 mutant embryos exhibited multiple cardiac defects including thin myocardium, ventricular septum defect, common atrioventricular valve, and double outlet right ventricle around E14.5. Moreover, we also detected reduced intramyocardial coronary arteries in BAF200 mutants, suggesting that BAF200 is required for proper migration and differentiation of subepicardial venous cells into arterial endothelial cells. Our work revealed that PBAF complex plays a critical role in heart morphogenesis and coronary artery angiogenesis.

  15. WinCC与S7-200系列PLC通信的实现

    Institute of Scientific and Technical Information of China (English)

    孙连生; 刘志韬

    2006-01-01

    针对控制系统中上位机与S7—200系列PLC(Program Logic Control)通信的实际问题.总结了使用WinCC组态软件上位机与S7—200系列PLC的通信方法,这几种方法在不同的控制系统中能较好解决上位机与S7~200系列PLC通信问题。

  16. RCRA facility investigation report for the 200-PO-1 operable unit. Revision 1

    International Nuclear Information System (INIS)

    This Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) report is prepared in support of the RFI/corrective measures study process for the 200-PO-1 Groundwater Operable Unit in the 200 East Area of the Hanford Site. This report summarizes existing information on this operable unit presented in the 200 East and PUREX Aggregate Area Management Study Reports, contaminant specific studies, available modeling data, and groundwater monitoring data summary reports. Existing contaminant data are screened against current regulatory limits to determine contaminants of potential concern (COPC). Each identified COPC is evaluated using well-specific and plume trend analyses

  17. 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program

    International Nuclear Information System (INIS)

    The 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program (Implementation Plan) addresses approximately 700 soil waste sites (and associated structures such as pipelines) resulting from the discharge of liquids and solids from processing facilities to the ground (e.g., ponds, ditches, cribs,burial grounds) in the 200 Areas and assigned to the Environmental Restoration Program. The Implementation Plan outlines the framework for implementing assessment activities in the 200 Areas to ensure consistency in documentation, level of characterization, and decision making. The Implementation Plan also consolidates background information and other typical work plan materials, to serve as a single referenceable source for this type of information

  18. Design study of 1.8 K 200 W helium refrigeration system

    International Nuclear Information System (INIS)

    The superconducting RF cavities of the superconducting proton linac will be cooled by superfluid helium below 2.0 K. The cooling test of the superconducting RF cavities will be required about 200 W of cooling power at 1.8 K. Refrigeration using superfluid helium is required a helium refrigeration system cooling down to 1.8 K. A cold compressor is a key component for the system. IHI carried out 1.8 K 200 W helium refrigeration system design for cooling test of the superconducting RF cavities. The preliminary design study of the 1.8 K 200 W helium refrigeration system is presented. (author)

  19. 从F200谈富士新一代Super CCD EXR

    Institute of Scientific and Technical Information of China (English)

    落单的鱼

    2009-01-01

    富士的F系列消费类相机是其主打“优秀成像”概念的系列相机.而FinePix F200EXR是F系列相机的最新旗舰型号。但是光看配置.F200和F100似乎没有什么变化.那么F200较F100到底有哪些改进之处呢?

  20. The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks' gestation.

    Science.gov (United States)

    Clark, David A; Arredondo, Jorge L; Dhesy-Thind, Sukhbinder

    2015-11-01

    CD200 expression in murine trophoblast and decidua prevents semi-allogeneic and LPS-induced abortions by binding to CD200 receptor-bearing cells to suppress NK activity, induces IDO in macrophages, and promotes the generation of regulatory T cell subsets. CD200 and its receptor CD200R1 reported in 7-9 weeks' gestation human villus trophoblasts are reduced in spontaneous abortion syncytiotrophoblasts. By specific antibody staining, we find that both CD200 and CD200R1 are expressed even earlier, by 5 weeks' gestation, by villus trophoblasts and by decidual cells. Expression of CD200 was validated using two independent antibodies. CD200-CD200R1 signaling may be required for human pregnancy success. PMID:26123445

  1. Hydrography, rivers, Published in 2008, 1:2400 (1in=200ft) scale, Hamilton County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Hydrography dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as 'rivers'....

  2. Zoning Districts, Published in 2009, 1:2400 (1in=200ft) scale, WABASH COUNTY GOVERNMENT.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Zoning Districts dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Hardcopy Maps information as of 2009. Data by this publisher...

  3. Zoning Districts, Published in 2009, 1:2400 (1in=200ft) scale, Dickinson County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Zoning Districts dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2009. Data by this...

  4. Doctor Offices, Published in 2008, 1:2400 (1in=200ft) scale, Shawano County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Doctor Offices dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2008. Data by this...

  5. Hydrography, Published in 2008, 1:2400 (1in=200ft) scale, Eau Claire County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Hydrography dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2008. Data by this publisher are...

  6. Railroad Lines, Published in 2008, 1:2400 (1in=200ft) scale, Eau Claire County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Railroad Lines dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Hardcopy Maps information as of 2008. Data by this publisher...

  7. Summary of radioactive solid waste received in the 200 Areas during calendar year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Hladek, K.L.

    1996-06-06

    Westinghouse Hanford Company manages and operates the Hanford Site 200 Area radioactive solid waste storage and disposal facilities for the US Department of Energy, Richland Operations Office. These facilities include radioactive solid waste disposal sites and radioactive solid waste storage areas. This document summarizes the amount of radioactive materials that have been buried and stored in the 200 Area radioactive solid waste storage and disposal facilities since startup in 1944 through calendar year 1995. This report does not include backlog waste, solid radioactive wastes in storage or disposed of in other areas, or facilities such as the underground tank farms. Unless packaged within the scope of WHC-EP-0063, Hanford Site Solid Waste Acceptance Criteria, liquid waste data are not included in this document. This annual report provides a summary of the radioactive solid waste received in the both the 200-East and 200-West Areas during the calendar year 1995.

  8. Recycling Facilities, Published in 2009, 1:2400 (1in=200ft) scale, City of Rome.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Recycling Facilities dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Other information as of 2009. Data by this publisher are...

  9. Dentist Offices, Published in 2008, 1:2400 (1in=200ft) scale, Shawano County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Dentist Offices dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2008. Data by this...

  10. 康斯登肖邦200周年腕表限量1810枚

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    康斯登(Frederique Constant)在去年向钢琴大师肖邦200周年冥诞致敬,推出了"肖邦200周年纪念表",今年再次推出"肖邦200周年纪念表",表盘改以优雅的珐琅材质呈现,整体更显古典气息。全球限量1810只。今年全新的"肖邦(Chopin)200周年纪念表"珐琅材质表盘款式,以2010年的版本为基础,在表盘上使用了白色珐琅打造,

  11. Cultural Resources, landmarks, Published in 2008, 1:2400 (1in=200ft) scale, Haskell County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cultural Resources dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  12. Zoning Districts, Published in 2012, 1:2400 (1in=200ft) scale, Sauk County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Zoning Districts dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2012. Data by this...

  13. 34 CFR 200.77 - Reservation of funds by an LEA.

    Science.gov (United States)

    2010-07-01

    ... development expenditure requirements under § 200.60; (e) Meet the requirements for parental involvement in... authorized activities, such as school improvement and coordinated services. (Authority: 20 U.S.C....

  14. 17 CFR 200.60 - Qualification to participate in particular matters.

    Science.gov (United States)

    2010-04-01

    ... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200... respect to any matter wherein he or any relatives or former business associates or clients are...

  15. Pharmacy Locations, Published in 2008, 1:2400 (1in=200ft) scale, Shawano County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Pharmacy Locations dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2008. Data by...

  16. Haridusministeerium kingib koolilõpetajatele 200 000 eest šokolaadi / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2006-01-01

    Haridus- ja Teadusministeerium kingib keskkoolide, gümnaasiumide ja kutsekoolide lõpetajatele 200 000 krooni eest Kalevi erikujundusega šokolaadi. Seda otsust kritiseerib endine haridusminister Tõnis Lukas

  17. Õpetajaks hakkamise eest võib tulevikus saada 200 000 krooni / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2007-01-01

    Isamaa ja Res Publica Liit lubab võimule pääsedes maksta esmakordselt tööle asuvale pedagoogilise kõrgharidusega õpetajale 200 000 krooni stardiraha. Endise haridusministri Tõnis Lukase selgitus

  18. Address Points, Published in 2008, 1:2400 (1in=200ft) scale, Meade County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Address Points dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. The extent of these data...

  19. Indian Reservations, Published in Not Provided, 1:2400 (1in=200ft) scale, Cherokee Co..

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Indian Reservations dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of Not Provided. Data by this...

  20. Address Points, Published in 2008, 1:2400 (1in=200ft) scale, Scott county.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Address Points dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. Data by this publisher are...

  1. Address Points, Published in 2013, 1:2400 (1in=200ft) scale, Oneida County Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Address Points dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Field Survey/GPS information as of 2013. Data by this publisher...

  2. The VASIMR[registered trademark] VF-200-1 ISS Experiment as a Laboratory for Astrophysics

    Science.gov (United States)

    Glover Tim W.; Squire, Jared P.; Longmier, Benjamin; Cassady, Leonard; Ilin, Andrew; Carter, Mark; Olsen, Chris S.; McCaskill, Greg; Diaz, Franklin Chang; Girimaji, Sharath; Araya, Daniel; Shebalin, John

    2010-01-01

    The VASIMR[R] Flight Experiment (VF-200-1) will be tested in space aboard the International Space Station (ISS) in about four years. It will consist of two 100 kW parallel plasma engines with opposite magnetic dipoles, resulting in a near zero-torque magnetic system. Electrical energy will come from ISS at low power level, be stored in batteries and used to fire the engine at 200 kW. The VF-200-1 project will provide a unique opportunity on the ISS National Laboratory for astrophysicists and space physicists to study the dynamic evolution of an expanding and reconnecting plasma loop. Here, we review the status of the project and discuss our current plans for computational modeling and in situ observation of a dynamic plasma loop on an experimental platform in low-Earth orbit. The VF-200-1 project is still in the early stages of development and we welcome new collaborators.

  3. Tourism Areas, Published in 2011, 1:2400 (1in=200ft) scale, Trempealeau County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Tourism Areas dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2011. Data by this publisher are...

  4. Color Hawaii Shaded Relief ? 200-Meter Resolution, Albers projection - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The color Hawaii shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Hawaii at a resolution of 200 meters. The NED...

  5. Grayscale Alaska Shaded Relief ? 200-Meter Resolution, Albers projection - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The grayscale Alaska shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Alaska at a resolution of 200 meters. The...

  6. Color Alaska Shaded Relief ? 200-Meter Resolution, Albers projection - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The color Alaska shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Alaska at a resolution of 200 meters. The NED...

  7. Grayscale Hawaii Shaded Relief ? 200-Meter Resolution, Albers projection - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The grayscale Hawaii shaded relief data were derived from National Elevation Dataset (NED) data, and show the terrain of Hawaii at a resolution of 200 meters. The...

  8. Emergency Shelters, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Emergency Shelters dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher...

  9. Fire Stations, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Fire Stations dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  10. Navigable Waters, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Navigable Waters dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher...

  11. Public Beaches, Published in 2008, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Public Beaches dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2008. Data by this publisher are...

  12. Navigable Waters, Published in 1996, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Navigable Waters dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 1996. Data by this publisher...

  13. Trails, Hiking, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Trails, Hiking dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  14. Fair Grounds, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Fair Grounds dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  15. Trails, Bike, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Trails, Bike dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  16. Dam Inventory, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Dam Inventory dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  17. Railroad Lines, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Railroad Lines dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher are...

  18. Police Stations, Published in 2007, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Police Stations dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. Data by this publisher...

  19. Ambulatory Surgical Facilities, Published in 2010, 1:2400 (1in=200ft) scale, Shawano County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Ambulatory Surgical Facilities dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2010....

  20. 17 CFR 200.30-10 - Delegation of authority to Chief Administrative Law Judge.

    Science.gov (United States)

    2010-04-01

    ... Organization and Program Management General Organization § 200.30-10 Delegation of authority to Chief... subpenas requiring the production of documentary or other tangible evidence at any designated place...

  1. The novel fluid loss additive HTF-200C for oil field cementing%新型固井降失水剂HTF-200C

    Institute of Scientific and Technical Information of China (English)

    郭锦棠; 卢海川; 刘硕琼; 靳建州; 于永金

    2012-01-01

    The domestic fluid loss additives often have lower thermal stability and poor salt-tolerance and their comprehensive properties are not good enough. To solve the problems, a novel cement fluid loss additive HTF-200C. Which can resist high temperature and high salt content, was synthesized using the monomers of 2-acrylamido-2-methyl-propane sulphonic acid (AMPS), N, N-dimethyl acrylamide (DMAA) and a new compound with double carboxyl by the method of aqueous solution polymerization. The microstructural characterization and application performance of HTF-200C show that the polymer with the structure of all the monomers has an excellent thermal stability and strong salt tolerance, and can be used in 200 "C or in saturated brine. And the problem of the normal fluid loss additive being easy to hydrolyze due to high temperature can be solved with HTF-200C. What's more, it can also deal with the bulge of thickening curve in consistency test. The cement slurry prepared mainly by HTF-200C presents good comprehensive properties such as low filtration, high thermal stability, strong salt tolerance, rapid development of strength in low temperature, without far delayed solidification, short transit time during thickening process, and so on. The cementing job quality of Well Chengu 1-3 in the Liaohe Oilfield is excellent after it is used.%针对目前中国常规固井降失水剂抗温抗盐能力差、综合性能欠佳的问题,以2-丙烯酰胺基-2-甲基丙磺酸(AMPS)、N,N-二甲基丙烯酰胺(DMAA)、新型双羧基化合物为单体,采用水溶液自由基聚合的方法合成了耐盐、抗高温的共聚物型固井水泥降失水剂HTF-200C.HTF-200C微观结构表征和应用性能综合评价表明,各单体成功参与聚合,共聚物热稳定性良好;该降失水剂控失水耐温可达200℃,抗盐达饱和,可解决常规降失水剂高温下易水解、稠化实验“鼓包”等问题;以HTF-200C为主剂的水泥浆体系失水量低、抗盐耐温

  2. A Comprehensive Review on miR-200c, A Promising Cancer Biomarker with Therapeutic Potential.

    Science.gov (United States)

    Kumar, Suresh; Nag, Alo; Mandal, Chandi C

    2015-01-01

    MicroRNAs (miRNAs) are small single stranded non coding RNA molecules (~22 nucleotides) which impede protein production by directly interacting with 3'untranslated regions of the target mRNAs. Interestingly, miR-200c is often dysregulated in various cancers that normally exhibits tumor suppressive behavior by blocking epithelial to mesenchymal transition (EMT) of cancer cells. However, elevation of miR-200c in various cancer tissues contradicts the tumor suppressive role of this microRNA. This review addresses the molecular mechanisms involved in the regulation of the endogenous level of miR-200c in various cancers such as breast, ovarian, prostate, endometrial, lungs, colon, pancreatic, etc. and its differential role in regulation of proliferation and EMT phenotype of cancer cells. Further, this review discusses whether abnormal level of miR-200c in cancer tissues or in blood circulation can be used as a biomarker. Importantly, how the level of miR-200c can be used to predict the effectiveness of the cancer therapy is also discussed. Accumulating evidences suggest that use of miR-200c alone may not be sufficient for treatment of cancer patients, but the combination of miR-200c with an anti-proliferating drug could be a better choice to prevent invasiveness of cancers as well as tumor growth both in primary and in metastatic sites. This article also proposes that the tumor microenvironment may have a role in influencing epigenetic silencing of miR-200c expression.

  3. Annex D-200 Area Interim Storage Area Final Safety Analysis Report [FSAR] [Section 1 & 2

    Energy Technology Data Exchange (ETDEWEB)

    CARRELL, R D

    2002-07-16

    The 200 Area Interim Storage Area (200 Area ISA) at the Hanford Site provides for the interim storage of non-defense reactor spent nuclear fuel (SNF) housed in aboveground dry cask storage systems. The 200 Area ISA is a relatively simple facility consisting of a boundary fence with gates, perimeter lighting, and concrete and gravel pads on which to place the dry storage casks. The fence supports safeguards and security and establishes a radiation protection buffer zone. The 200 Area ISA is nominally 200,000 ft{sup 2} and is located west of the Canister Storage Building (CSB). Interim storage at the 200 Area ISA is intended for a period of up to 40 years until the materials are shipped off-site to a disposal facility. This Final Safety Analysis Report (FSAR) does not address removal from storage or shipment from the 200 Area ISA. Three different SNF types contained in three different dry cask storage systems are to be stored at the 200 Area ISA, as follows: (1) Fast Flux Test Facility Fuel--Fifty-three interim storage casks (ISC), each holding a core component container (CCC), will be used to store the Fast Flux Test Facility (FFTF) SNF currently in the 400 Area. (2) Neutron Radiography Facility (NRF) TRIGA'--One Rad-Vault' container will store two DOT-6M3 containers and six NRF TRIGA casks currently stored in the 400 Area. (3) Commercial Light Water Reactor Fuel--Six International Standards Organization (ISO) containers, each holding a NAC-I cask4 with an inner commercial light water reactor (LWR) canister, will be used for commercial LWR SNF from the 300 Area. An aboveground dry cask storage location is necessary for the spent fuel because the current storage facilities are being shut down and deactivated. The spent fuel is being transferred to interim storage because there is no permanent repository storage currently available.

  4. In situ Measurements of the SPS 200MHz Accelerating Cavity III

    CERN Document Server

    Kramer, Patrick; Caspers, Fritz; Vollinger, Christine; Montesinos, Eric; CERN. Geneva. ATS Department

    2015-01-01

    The main 200MHz travelling wave RF system of the SPS consists of two 5-tank and two 4-tank cavities. This system will be modified during LS 2, and the preparation work has already started. The 5 tank 200MHz travelling wave cavity III was measured in reflection. This Internal Note presents results obtained for the matching of cavity and feeder line, by looking at both frequency and time domain data. Techniques for estimating the feeder line attenuation are also presented.

  5. ABB公司的A200-L涡轮增压器

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    ABB Turbocharging宣布,公司为二冲程低速发动机专门开发的新一代A200-L单段涡轮增压器,是涡轮增压器技术开发上的一个飞跃。A200-L的压缩机经过了优化,能够显著增加进气流量。

  6. Epithelial cell differentiation regulated by MicroRNA-200a in mammary glands.

    Directory of Open Access Journals (Sweden)

    Kentaro Nagaoka

    Full Text Available Mammary gland epithelial cells undergo periodic cycles of proliferation, differentiation, and involution. Many studies have reported that miRNAs, which are small, non-coding RNAs, influence a variety of biological processes during posttranscriptional regulation. Here, we found that one miRNA, miR-200a, was relatively highly expressed in epithelial cell-rich organs such as mammary glands, lung, and kidney in mice. In mammary glands, miR-200a expression increased during mid-pregnancy through lactation; its expression was stimulated by lactogenic hormone treatment of mammary epithelial cells. Lactogenic hormone also induced the expression of milk protein ß-casein mRNA (a marker of cell differentiation and E-cadherin mRNA (a marker of epithelial cells. However, knockdown of miR-200a prevented increases in ß-casein and E-cadherin mRNA expression. Protein analysis revealed that E-cadherin signal was decreased and ZEB1 (a marker of EMT was increased following miR-200a knockdown. Finally, in a three-dimensional culture system modeling lumen-containing mammary ducts, miR-200a knockdown decreased the cavity formation rate and suppressed claudin-3 and par-6b expression, indicating reduced epithelial cell polarity. These observations suggest that miR-200a is important for maintaining the epithelial cell phenotype, which contributes to lactogenic hormone induction of cellular differentiation in mammary glands.

  7. DX-200数字式中波发射机检测电路设计%DX-200 digital AM transmitter detector circuit design

    Institute of Scientific and Technical Information of China (English)

    杨帆

    2015-01-01

    随着科学技术的发展,电工电子在科学技术上应用新型科学技术,保证了其稳定性的同时,对于生产建设用电保证等问题上,发挥了日益重要的作用。DX-200是在发射机的调制编码板上设置电缆联锁检测电路,这在降低故障损失以及不损坏元器件方面,发挥了极大的作用。DX-200数字式中波发射机采用了模块与模块的串接,电缆联锁比较器与保险监测比较器的并联方式,对电路进行分析,对设备的运行状态以及预防设备故障方面,具有重要意义。本文主要研究了基于DX-200数字式中波发射机对电路检测的设计,以及该装置如何进行实际运作进行了相应的研究和分析。%With the development of science and technology,electronics science and technology in the application of new science and technology,to ensure its stability,while construction for the production of electricity to ensure that such issues played an increasingly important role.DX-200 is set up cable interlock detection circuit in the transmitter modulation and coding plates,which reduce losses and no damage to components malfunction has played a great role.DX-200 digital AM transmitter with a series,the cable interlock comparator and insurance monitoring comparator modules and modules in parallel,the circuit analysis,operational status of the equipment as well as the prevention of equipment failures,an important significance.This paper studies on DX-200 digital AM transmitter circuit test design,and how the actual operation of the device for the corresponding research and analysis.

  8. miR-200家族在乳腺癌中的表达及其临床意义%The expression and its clinical significance of miR-200 family members in breast cancer

    Institute of Scientific and Technical Information of China (English)

    杨平安; 邢程; 王如娟

    2016-01-01

    目的 探讨miR-200家族成员在乳腺癌中的表达及其临床意义.方法 实时定量PCR和原位杂交分析乳腺癌组织中miR-200家族5个成员的表达情况.单因素和多因素分析miR-200a、miR-200b和miR-200c表达与乳腺癌临床病理参数和预后之间的相关性.结果 miR-200a、miR-200b和miR-200c在乳腺癌组织中的表达明显低于正常乳腺上皮组织,差异有统计学意义(P<0.01).miR-200a和miR-200b低表达与乳腺癌分期更晚、分级更高有关,而miR-200e低表达仅与分期更晚有关.多元回归分析表明,miR-200a、miR-200b和miR-200c低表达与乳腺癌患者生存期更短有关(P<0.01),miR-200a、miR-200b和miR-200c是乳腺癌患者预后的独立预测因子.结论 miR-200a、miR-200b和miR-200e表达下调能够促进肿瘤进展,是预测乳腺癌患者预后的可靠指标,miR-200a、miR-200b和miR-200c也具有成为乳腺癌靶向治疗靶点的潜力.

  9. Omron c200h-plc program design and application%欧姆龙C200 H型PLC编程设计精讲实例

    Institute of Scientific and Technical Information of China (English)

    高永斌

    2014-01-01

    The article introduces the feature of the Omron C200H-PLC,analyses some typical circuits,gives the I/O allocation table,draws the wiring diagram,designs the ladder diagrams that meet the control requirement, summarizes three kinds of PLC programmed design methods.%介绍了欧姆龙(OMRON)C200H_PLC 的性能特点,通过几个典型电路的分析,列出 I/O 分配表、画出接线图,设计出符合控制要求的梯形图,总结出3种 PLC 程序的设计方法。

  10. Analysis of 200 Cases of Pathological Pregnancy of Advanced Maternal Age%高龄产妇200例病理妊娠分析

    Institute of Scientific and Technical Information of China (English)

    侯玉琼

    2013-01-01

    目的 通过实验讨论研究高龄产妇的病理性妊娠产生时的状况.方法将高龄孕妇200例和年龄<35岁产妇200例配合搭对两组妊娠发生状况.结果高龄孕妇组妊娠期间患有高血压等几率显著大于对照组.结论高龄产妇病理妊娠产生机会比率大,应强化高龄产妇期间护理.

  11. On the Structure and Maintenance of XHX200 X-ray Machine%XHX200型X光机结构分析及保养技巧

    Institute of Scientific and Technical Information of China (English)

    张日文

    2015-01-01

    This paper analyzed the actual structure of XHX200 medical X-ray machine systematicaly. Based on the working experience of many years, the author also put forward some maintenance tips during instalation, use and cleaning, which can facilitate the machine’s safe operation and life extension.%本文系统分析了X H X200型医用X光机的实际结构,并根据多年工作经验从安装、使用及清洁等环节提出有利于设备安全运行和使用寿命延长的保养技巧。

  12. On the Structure and Maintenance of XHX200 X-ray Machine%XHX200型X光机结构分析及保养技巧

    Institute of Scientific and Technical Information of China (English)

    张日文

    2014-01-01

    本文系统分析了XHX200型医用X光机的实际结构,并根据多年工作经验从安装、使用及清洁等环节提出有利于设备安全运行和使用寿命延长的保养技巧。%This paper analyzed the actual structure of XHX200 medical X-ray machine systematical y.Based on the working experience of many years, the author also put forward some maintenance tips during instal ation,use and cleaning, which can facilitate the machine's safe operation and life extension.

  13. 电切法袖套式包皮环切术200例临床分析%Electric cutting sleeve circumcision : clinical analysis of 200 cases

    Institute of Scientific and Technical Information of China (English)

    邹义华; 陈晓峰; 陈善群

    2012-01-01

    Objective:To evaluate the safety and effect of electric cutting sleeve circumcision for treatment of patients with redundant prepuce and phimosis. Method: Using electric cutting sleeve circumcision in 200 cases, the curative effect, complications and their prevention measures were analyzed. Result:The 200 cases of electric cutting sleeve circumcision show little bleeding, neat cutting, slight postoperative wound edema, little scar and satisfactory appearance of penis. Conclusion: With more satisfactory curative effect and fewer complications, Electric sleeve circumcision for treatment of patients with redundant prepuce and phimosis is worthy of clinical application.%目的:探讨电切法袖套式包皮环切术治疗包皮过长与包茎患者的安全性与疗效.方法:采用电切法袖套式包皮环切术治疗包皮过长与包茎患者200例,分析手术效果、并发症及其预防措施.结果:200例电切法袖套式包皮环切术出血少、切缘整齐,术后包皮水肿轻微,切口均一期愈合,癜痕少,阴茎外观满意.结论:电切法袖套式包皮环切术治疗包皮过长与包茎患者效果满意,并发症少,值得临床推广.

  14. FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT

    Energy Technology Data Exchange (ETDEWEB)

    BYRNES ME

    2008-07-18

    The Hanford Site, managed by the U.S. Department of Energy (DOE), encompasses approximately 1,517 km{sup 2} (586 mi{sup 2}) in the Columbia Basin of south-central Washington State. In 1989, the U.S. Environmental Protection Agency (EPA) placed the 100, 200, 300, and 1100 Areas of the Hanford Site on the 40 Code of Federal Regulations (CFR) 300, 'National Oil and Hazardous Substances Pollution Contingency Plan' National Contingency Plan [NCPD], Appendix B, 'National Priorities List' (NPL), pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 200 Areas NPL sites consist of the 200 West and 200 East Areas (Figure 1-1). The 200 Areas contain waste management facilities, inactive irradiated fuel reprocessing facilities, and the 200 North Area (formerly used for interim storage and staging of irradiated fuel). Several waste sites in the 600 Area, located near the 200 Areas, also are included in the 200 Areas NPL site. The 200 Areas NPL site is in a region referred to as the 'Central Plateau' and consists of approximately 700 waste sites, excluding sites assigned to the tank farm waste management areas (WMAs). The 200-ZP-1 Groundwater Operable Unit (OU) consists of the groundwater located under the northern portion of the 200 West Area. Waste sources that contributed to the 200-ZP-1 OU included cribs and trenches that received liquid and/or solid waste in the past from the Z Plant and T Plant aggregate areas, WMA-T, WMA-TX/TY, and the State-Approved Land Disposal Site (SALDS). This feasibility study (FS) for the 200-ZP-1 Groundwater OU was prepared in accordance with the requirements of CERCLA decision documents. These decision documents are part of the Administrative Record for the selection of remedial actions for each waste site and present the selected remedial actions that are chosen in accordance with CERCLA, as amended by the Superfund Amendments and Reauthorization Act of 1986

  15. Circulating microRNA-200 Family as Diagnostic Marker in Hepatocellular Carcinoma.

    Directory of Open Access Journals (Sweden)

    Sameer A Dhayat

    Full Text Available In this clinical study, we aimed to evaluate the role of circulating microRNA-200 family as a non-invasive tool to identify patients with cirrhosis-associated hepatocellular carcinoma (HCC.Prognosis of HCC remains poor with increasing incidence worldwide, mainly related to liver cirrhosis. So far, no reliable molecular targets exist for early detection of HCC at surgically manageable stages. Recently, we identified members of the microRNA-200 family as potential diagnostic markers of cirrhosis-associated HCC in patient tissue samples. Their value as circulating biomarkers for HCC remained undefined.Blood samples and clinicopathological data of consecutive patients with liver diseases were collected prospectively. Expression of the microRNA-200 family was investigated by qRT-PCR in blood serum samples of 22 HCC patients with and without cirrhosis. Serum samples of patients with non-cancerous chronic liver cirrhosis (n = 22 and of healthy volunteers (n = 15 served as controls.MicroRNA-141 and microRNA-200a were significantly downregulated in blood serum of patients with HCC compared to liver cirrhosis (p<0.007 and healthy controls (p<0.002. MicroRNA-141 and microRNA-200a could well discriminate patients with cirrhosis-associated HCC from healthy volunteers with area under the receiver-operating characteristic curve (AUC values of 0.85 and 0.82, respectively. Additionally, both microRNAs could differentiate between HCC and non-cancerous liver cirrhosis with a fair accuracy.Circulating microRNA-200 family members are significantly deregulated in patients with HCC and liver cirrhosis. Further studies are necessary to confirm the diagnostic value of the microRNA-200 family as accurate serum marker for cirrhosis-associated HCC.

  16. Historical records of radioactive contamination in biota at the 200 Areas of the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, A.R.; Markes, B.M.; Schmidt, J.W.; Shah, A.N.; Weiss, S.G.; Wilson, K.J.

    1994-06-01

    This document summarizes and reports a literature search of 85 environmental monitoring records of wildlife and vegetation (biota) at the 200 East Area and the 200 West Area of the Hanford Site since 1965. These records were published annually and provided the majority of the data in this report. Additional sources of data have included records of specific facilities, such as site characterization documents and preoperational environmental surveys. These documents have been released for public use. Records before 1965 were still being researched and therefore not included in this document. The intent of compiling these data into a single source was to identify past and current concentrations of radionuclides in biota at specific facilities and waste sites within each operable unit that may be used to help guide cleanup activities in the 200 Areas to be completed under the Comprehensive Environmental Response and Liability Act (CERCLA). The 200 East Area and 200 West Area were the locations of the Hanford Site separation and process facilities and waste management units. For the purposes of this document, a sample was of interest if a Geiger-Mueller counter equipped with a pancake probe-indicated beta/gamma emitting radioactivity above 200 counts per minute (cpm), or if laboratory radioanalyses indicated a radionuclide concentration equaled or exceeded 10 picocuries per gram (pCi/g). About 4,500 individual cases of monitoring for radionuclide uptake or transport in biota in the 200 Areas environs were included in the documents reviewed. About 1,900 (i.e., 42%) of these biota had radionuclide concentrations in excess of 10 pCi/g. These radionuclide transport or uptake cases were distributed among 45 species of wildlife (primarily small mammals and feces) and 30 species of vegetation. The wildlife species most commonly associated with radioactive contamination were the house mouse and the deer mouse and of vegetation species, the Russian thistle.

  17. Phase 1 remedial investigation report for 200-BP-1 operable unit. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The US Department of Energy (DOE) Hanford Site, in Washington State is organized into numerically designated operational areas including the 100, 200, 300, 400, 600, and 1100 Areas. The US Environmental Protection Agency (EPA), in November 1989 included the 200 Areas of the Hanford Site on the National Priority List (NPL) under the Comprehensive Environmental Response, Compensation and Liability Act of 1980 (CERCLA). Inclusion on the NPL initiated the remedial investigation (RD process for the 200-BP-1 operable unit. These efforts are being addressed through the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1989) which was negotiated and approved by the DOE, the EPA, and the State of Washington Department of Ecology (Ecology) in May 1989. This agreement, known as the Tri-Party Agreement, governs all CERCLA efforts at Hanford. In March of 1990, the Department of Energy, Richland Operations (DOE-RL) issued a Remedial Investigation/Feasibility Study (RI/FS) work plan (DOE-RL 1990a) for the 200-BP-1 operable unit. The work plan initiated the first phase of site characterization activities associated with the 200-BP-1 operable unit. The purpose of the 200-BP-1 operable unit RI is to gather and develop the necessary information to adequately understand the risks to human health and the environment posed by the site and to support the development and analysis of remedial alternatives during the FS. The RI analysis will, in turn, be used by Tri-Party Agreement signatories to make a risk-management-based selection of remedies for the releases of hazardous substances that have occurred from the 200-BP-1 operable unit.

  18. Nanoparticle-mediated miR200-b delivery for the treatment of diabetic retinopathy.

    Science.gov (United States)

    Mitra, Rajendra Narayan; Nichols, Chance A; Guo, Junjing; Makkia, Rasha; Cooper, Mark J; Naash, Muna I; Han, Zongchao

    2016-08-28

    We recently reported that the Ins2(Akita) mouse is a good model for late-onset diabetic retinopathy. Here, we investigated the effect of miR200-b, a potential anti-angiogenic factor, on VEGF receptor 2 (VEGFR-2) expression and to determine the underlying angiogenic response in mouse endothelial cells, and in retinas from aged Ins2(Akita) mice. MiR200-b and its native flanking sequences were amplified and cloned into a pCAG-eGFP vector directed by the ubiquitous CAG promoter (namely pCAG-miR200-b-IRES-eGFP). The plasmid was compacted by CK30PEG10K into DNA nanoparticles (NPs) for in vivo delivery. Murine endothelial cell line, SVEC4-10, was first transfected with the plasmid. The mRNA levels of VEGF and VEGFR-2 were quantified by qRT-PCR and showed significant reduction in message expression compared with lipofectamine-transfected cells. Transfection of miR200-b suppressed the migration of SVEC4-10 cells. There was a significant inverse correlation between the level of expression of miR200-b and VEGFR-2. Intravitreal injection of miR200-b DNA NPs significantly reduced protein levels of VEGFR-2 as revealed by western blot and markedly suppressed angiogenesis as evaluated by fundus imaging in aged Ins2(Akita) mice even after 3months of post-injection. These findings suggest that NP-mediated miR200-b delivery has negatively regulated VEGFR-2 expression in vivo. PMID:27297781

  19. Phase 1 remedial investigation report for 200-BP-1 operable unit

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) Hanford Site, in Washington State is organized into numerically designated operational areas including the 100, 200, 300, 400, 600, and 1100 Areas. The US Environmental Protection Agency (EPA), in November 1989 included the 200 Areas of the Hanford Site on the National Priority List (NPL) under the Comprehensive Environmental Response, Compensation and Liability Act of 1980 (CERCLA). Inclusion on the NPL initiated the remedial investigation (RD process for the 200-BP-1 operable unit. These efforts are being addressed through the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1989) which was negotiated and approved by the DOE, the EPA, and the State of Washington Department of Ecology (Ecology) in May 1989. This agreement, known as the Tri-Party Agreement, governs all CERCLA efforts at Hanford. In March of 1990, the Department of Energy, Richland Operations (DOE-RL) issued a Remedial Investigation/Feasibility Study (RI/FS) work plan (DOE-RL 1990a) for the 200-BP-1 operable unit. The work plan initiated the first phase of site characterization activities associated with the 200-BP-1 operable unit. The purpose of the 200-BP-1 operable unit RI is to gather and develop the necessary information to adequately understand the risks to human health and the environment posed by the site and to support the development and analysis of remedial alternatives during the FS. The RI analysis will, in turn, be used by Tri-Party Agreement signatories to make a risk-management-based selection of remedies for the releases of hazardous substances that have occurred from the 200-BP-1 operable unit

  20. Expression and clinical significance of miR-181a, miR-200a, miR-200c in lung cancer tissues and cells%肺癌细胞及组织中miR-181a、miR-200a、miR-200c表达变化及意义

    Institute of Scientific and Technical Information of China (English)

    王勇; 李宇男; 于晓松

    2014-01-01

    Objective To observe the expression and significance of miR-181a, miR-200a, miR-200c in lung cancer tissues and cells.Methods RT-PCR method was used to detect the expression of miR-181a, miR-200a, miR-200c in lung cancer cell lines NCI-H1299, NCI-H358, H460, A549 and normal human bronchial epithelial cell line HBE , and in the lung cancer tissues and adjacent tissues .To analyze the relationship between the expression of miR-181a, miR-200a, miR-200c and clinicopathological parameters of lung cancer by means of Mann-Whitney.Results miR-181a expression in NCI-H1299, NCI-H358 and A549 were lower than that in HBE (all P0.05).miR-200c expression in lung cancer tissues was higher than that in cancer-adjacent tissues (P<0.01).miR-200a expression in the lung cancer patients with lymphatic metastasis was lower than that in lung cancer patients without lymphatic metastasis (P<0.01).Conclusions The expression of miR-181a, miR-200a were generally decreased , while miR-200c was generally increased in lung cancer cell lines and tissues , which maight be related to the occur of lung cancer .%目的:观察肺癌细胞及组织中 miR-181a、miR-200a、miR-200c 的表达变化,并探讨其临床意义。方法选择人肺癌细胞系NCI-H1299、NCI-H358、H460、A549及人正常支气管上皮细胞HBE,10例肺癌患者的癌组织及其相应癌旁组织。采用RT-PCR法检测各细胞系及组织中的miR-181a、miR-200a、miR-200c,并分析miRNA表达与临床参数的关系。结果 NCI-H1299、NCI-H358、A549细胞中miR-181a相对表达量均低于HBE细胞,NCI-H1299、NCI-H358、H460、A549细胞中miR-200a相对表达量均低于HBE细胞,NCI-H358、H460细胞中miR-200c相对表达量均高于HBE细胞,P均<0.05。肺癌及癌旁组织中miR-181a和miR-200a相对表达量比较,P均>0.05;肺癌组织中miR-200c相对表达量高于癌旁组织,P<0.01。有淋巴结转移的肺癌患者miR-200a相对表达量低

  1. FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT

    Energy Technology Data Exchange (ETDEWEB)

    BYRNES ME

    2008-07-18

    The Hanford Site, managed by the U.S. Department of Energy (DOE), encompasses approximately 1,517 km{sup 2} (586 mi{sup 2}) in the Columbia Basin of south-central Washington State. In 1989, the U.S. Environmental Protection Agency (EPA) placed the 100, 200, 300, and 1100 Areas of the Hanford Site on the 40 Code of Federal Regulations (CFR) 300, 'National Oil and Hazardous Substances Pollution Contingency Plan' National Contingency Plan [NCPD], Appendix B, 'National Priorities List' (NPL), pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 200 Areas NPL sites consist of the 200 West and 200 East Areas (Figure 1-1). The 200 Areas contain waste management facilities, inactive irradiated fuel reprocessing facilities, and the 200 North Area (formerly used for interim storage and staging of irradiated fuel). Several waste sites in the 600 Area, located near the 200 Areas, also are included in the 200 Areas NPL site. The 200 Areas NPL site is in a region referred to as the 'Central Plateau' and consists of approximately 700 waste sites, excluding sites assigned to the tank farm waste management areas (WMAs). The 200-ZP-1 Groundwater Operable Unit (OU) consists of the groundwater located under the northern portion of the 200 West Area. Waste sources that contributed to the 200-ZP-1 OU included cribs and trenches that received liquid and/or solid waste in the past from the Z Plant and T Plant aggregate areas, WMA-T, WMA-TX/TY, and the State-Approved Land Disposal Site (SALDS). This feasibility study (FS) for the 200-ZP-1 Groundwater OU was prepared in accordance with the requirements of CERCLA decision documents. These decision documents are part of the Administrative Record for the selection of remedial actions for each waste site and present the selected remedial actions that are chosen in accordance with CERCLA, as amended by the Superfund Amendments and Reauthorization Act of 1986

  2. MicroRNA-200 Family Profile: A Promising Ancillary Tool for Accurate Cancer Diagnosis.

    Science.gov (United States)

    Liu, Xiaodong; Zhang, Jianhua; Xie, Botao; Li, Hao; Shen, Jihong; Chen, Jianheng

    2016-01-01

    Cancer is one of the most threatening diseases in the world and great interests have been paid to discover accurate and noninvasive methods for cancer diagnosis. The value of microRNA-200 (miRNA-200, miR-200) family has been revealed in many studies. However, the results from various studies were inconsistent, and thus a meta-analysis was designed and performed to assess the overall value of miRNA200 in cancer diagnosis. Relevant studies were searched electronically from the following databases: PubMed, Embase, Web of Science, the Cochrane Library, and Chinese National Knowledge Infrastructure. Keyword combined with "miR-200," "cancer," and "diagnosis" in any fields was used for searching relevant studies. Then, the pooled sensitivity, specificity, area under the curve (AUC), and partial AUC were calculated using the random-effects model. Heterogeneity among individual studies was also explored by subgroup analyses. A total of 28 studies from 18 articles with an overall sample size of 3676 subjects (2097 patients and 1579 controls) were included in this meta-analysis. The overall sensitivity and specificity with 95% confidence intervals (95% CIs) are 0.709 (95% CI: 0.657-0.755) and 0.667 (95% CI: 0.617-0.713), respectively. Additionally, AUC and partial AUC for the pooled data is 0.735 and 0.627, respectively. Subgroup analyses revealed that using miRNA-200 family for cancer diagnosis is more effective in white than in Asian ethnic groups. In addition, cancer diagnosis by miRNA using circulating specimen is more effective than that using noncirculating specimen. Finally, miRNA is more accurate in diagnosing endometrial cancer than other types of cancer, and some miRNA family members (miR-200b and miR-429) have superior diagnostic accuracy than other miR-200 family members. In conclusion, the profiling of miRNA-200 family is likely to be a valuable tool in cancer detection and diagnosis.

  3. Continuous pulse oximetry in the general surgical ward: Nellcor N-200 versus Nellcor N-3000

    DEFF Research Database (Denmark)

    Christensen, M; Lie, C; Rosenberg, J

    1999-01-01

    Symphony N-3000 with the Nellcor N-200 pulse oximeter, when monitoring patients in the general surgical ward. Twenty-two patients were monitored during unrestricted ward activities for a total of 275 h with a N-3000 and a N-200 pulse oximeter simultaneously. Data were analysed for lack of concordance...... between the two pulse oximeters with respect to frequency of registered hypoxaemic episodes and thus the amount of time spent in the alarm state. The median number of desaturation episodes with the N-200 was 18 (range 0-511) compared with four (range 0-476) with the N-3000 (p ... of drop-outs (loss of signal) was 13 (range 1-46) with the N-200 compared with nine (2-41) with the N-3000 (p = 0.06). The N-200 registered saturation values of 85% or below for 23% of the observation time compared with 6% of the observation time with the N-3000 pulse oximeter (p

  4. Conceptual design report, 200 Area sanitary sewer system: Project 96L-EWL-116

    International Nuclear Information System (INIS)

    Project L-116 will install an integrated sanitary sewer system in the 200 Area. This new system will connect existing sewer systems for facilities that have a foreseeable future, provide capacity and routing for future facilities, and install new septic sewer systems for existing facilities that cannot be feasibly connected to the new sewer system and have a mission that will extend beyond the year 2000. Project L-116 will construct a sanitary sewer collection, treatment, and disposal system for facilities in the 200-East and -West Areas and adjacent areas located on the 200 Area plateau. The existing septic systems will be abandoned or decommissioned in accordance with applicable Washington State and local codes and regulations. The conceptual design for the sanitary sewer system is designed around population forecasts of 5,000 people for 200-West Area and 9,000 people for 200-East Area. The definitive design will be based on the latest forecast populations at the time definitive design is initiated

  5. JAERI 200 kV Electron Gun with an NEA-GaAs Photocathode

    CERN Document Server

    Nishitani, Tomohiro; Kikuzawa, Nobuhiro; John Minehara, Eisuke; Nagai, Ryoji; Nishimori, Nobuyuki; Sawamura, Masaru; Yamauchi, T

    2004-01-01

    The GaAs photocathode with negative electron affinity surface (NEA-GaAs) has been expected to be low emittance (<0.5 πmm・mrad) electron beam source. In order to generate low emittance electron beam required from ERL-FEL, we have started the developmental program of a 200keV electron gun with the NEA-GaAs photocathode for the first time in JAERI. An NEA surface has the problem that lifetime is limited by gun vacuum condition and by ion back bombardment between anode- and cathode-electrode. In order to long an NEA surface lifetime, the JAERI 200keV electron gun system consists of a 200kV DC-gun chamber on extreme high vacuum condition and an NEA activation chamber with load-lock system.

  6. Dry-type 50 MW, 200 kV Tesla transformer for compact pulse generator

    International Nuclear Information System (INIS)

    Full text: A 15V/200kV, 2μs air-core pulse transformer has been designed and fabricated for a prototype compact pulse generator for generation of intense pulsed electron beams. The transformer can deliver 50 to 100J energy at 50 MW peak power to charge a pulse forming line at 200 kV in 2μs time, which on discharge produces 200kV, 50ns HV pulse. This pulse transformer has also been used for surface flashover studies on insulators in vacuum and transformer oil mediums for sub-micro second region. In this paper, design details of pulse transformer, the test results and a comparative discussion with the conventional systems has been presented in brief

  7. Development of a 1 kW, 200 C Mapham Inventor

    Science.gov (United States)

    Hammoud, Ahmad; Gerber, Scott; Bauman, Eric; Overton, Eric; Myers, Ira; Bercaw, Robert

    1995-01-01

    Electronic systems and components are often exposed to high temperature environment in space-based applications, nuclear power facilities, and geothermal energy extraction fields. A key requirement for these systems is, therefore, to withstand the high temperature exposure while maintaining efficient and reliable operation. Efforts were taken to design and develop a high temperature power inverter capable of 200 C operation. A 1 kW, 20 kHz Mapham inverter was designed and evaluated as a function of temperature at different load levels. The inverter system, excluding its input, control, and logic circuits, was characterized at temperatures from ambient to 200 C at 0%, 50%, and 100% resistive loading. With an applied input voltage of 75 VDC, the inverter produced an output of 250 VAC. The results obtained, which indicate good operational characteristics of the inverter up to 200 C, are presented and discussed.

  8. Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer

    Directory of Open Access Journals (Sweden)

    Kan Casina WS

    2012-12-01

    Full Text Available Abstract Background There is a critical need for improved diagnostic markers for high grade serous epithelial ovarian cancer (SEOC. MicroRNAs are stable in the circulation and may have utility as biomarkers of malignancy. We investigated whether levels of serum microRNA could discriminate women with high-grade SEOC from age matched healthy volunteers. Methods To identify microRNA of interest, microRNA expression profiling was performed on 4 SEOC cell lines and normal human ovarian surface epithelial cells. Total RNA was extracted from 500 μL aliquots of serum collected from patients with SEOC (n = 28 and age-matched healthy donors (n = 28. Serum microRNA levels were assessed by quantitative RT-PCR following preamplification. Results microRNA (miR-182, miR-200a, miR-200b and miR-200c were highly overexpressed in the SEOC cell lines relative to normal human ovarian surface epithelial cells and were assessed in RNA extracted from serum as candidate biomarkers. miR-103, miR-92a and miR -638 had relatively invariant expression across all ovarian cell lines, and with small-nucleolar C/D box 48 (RNU48 were assessed in RNA extracted from serum as candidate endogenous normalizers. No correlation between serum levels and age were observed (age range 30-79 years for any of these microRNA or RNU48. Individually, miR-200a, miR-200b and miR-200c normalized to serum volume and miR-103 were significantly higher in serum of the SEOC cohort (P  Conclusions We identified serum microRNAs able to discriminate patients with high grade SEOC from age-matched healthy controls. The addition of these microRNAs to current testing regimes may improve diagnosis for women with SEOC.

  9. Pilot-scale treatability test plan for the 200-BP-5 operable unit

    International Nuclear Information System (INIS)

    This document presents the treatability test plan for pilot-scale pump and treat testing at the 200-BP-5 Operable Unit. This treatability test plan has been prepared in response to an agreement between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology), as documented in Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1989a) Change Control Form M-13-93-03 (Ecology et al. 1994) and a recent 200 NPL Agreement Change Control Form (Appendix A). The agreement also requires that, following completion of the activities described in this test plan, a 200-BP-5 Operable Unit Interim Remedial Measure (IRM) Proposed Plan be developed for use in preparing an Interim Action Record of Decision (ROD). The IRM Proposed Plan will be supported by the results of this treatability test plan, as well as by other 200-BP-5 Operable Unit activities (e.g., development of a qualitative risk assessment). Once issued, the Interim Action ROD will specify the interim action(s) for groundwater contamination at the 200-BP-5 Operable Unit. The treatability test approach is to conduct a pilot-scale pump and treat test for each of the two contaminant plumes associated with the 200-BP-5 Operable Unit. Primary contaminants of concern are 99Tc and 60Co for underwater affected by past discharges to the 216-BY Cribs, and 90Sr, 239/240Pu, and Cs for groundwater affected by past discharges to the 216-B-5 Reverse Well. The purpose of the pilot-scale treatability testing presented in this testplan is to provide the data basis for preparing an IRM Proposed Plan. To achieve this objective, treatability testing must: Assess the performance of groundwater pumping with respect to the ability to extract a significant amount of the primary contaminant mass present in the two contaminant plumes

  10. Development of the CCP-200 mathematical model for Syzran CHPP using the Thermolib software package

    Science.gov (United States)

    Usov, S. V.; Kudinov, A. A.

    2016-04-01

    Simplified cycle diagram of the CCP-200 power generating unit of Syzran CHPP containing two gas turbines PG6111FA with generators, two steam recovery boilers KUP-110/15-8.0/0.7-540/200, and one steam turbine Siemens SST-600 (one-cylinder with two variable heat extraction units of 60/75 MW in heatextraction and condensing modes, accordingly) with S-GEN5-100 generators was presented. Results of experimental guarantee tests of the CCP-200 steam-gas unit are given. Brief description of the Thermolib application for the MatLab Simulink software package is given. Basic equations used in Thermolib for modeling thermo-technical processes are given. Mathematical models of gas-turbine plant, heat-recovery steam generator, steam turbine and integrated plant for power generating unit CCP-200 of Syzran CHPP were developed with the help of MatLab Simulink and Thermolib. The simulation technique at different ambient temperature values was used in order to get characteristics of the developed mathematical model. Graphic comparison of some characteristics of the CCP-200 simulation model (gas temperature behind gas turbine, gas turbine and combined cycle plant capacity, high and low pressure steam consumption and feed water consumption for high and low pressure economizers) with actual characteristics of the steam-gas unit received at experimental (field) guarantee tests at different ambient temperature are shown. It is shown that the chosen degrees of complexity, characteristics of the CCP-200 simulation model, developed by Thermolib, adequately correspond to the actual characteristics of the steam-gas unit received at experimental (field) guarantee tests; this allows considering the developed mathematical model as adequate and acceptable it for further work.

  11. Melanoma cell expression of CD200 inhibits tumor formation and lung metastasis via inhibition of myeloid cell functions.

    Directory of Open Access Journals (Sweden)

    Fatemeh Talebian

    Full Text Available CD200 is a cell surface glycoprotein that functions through engaging CD200 receptor on cells of the myeloid lineage and inhibits their functions. Expression of CD200 has been implicated in a variety of human cancer cells including melanoma cells and has been thought to play a protumor role. To investigate the role of cancer cell expression of CD200 in tumor formation and metastasis, we generated CD200-positive and CD200-negative B16 melanoma cells. Subcutaneous injection of CD200-positive B16 melanoma cells inhibited tumor formation and growth in C57BL/6 mice but not in Rag1⁻/⁻C57BL/6 mice. However, i.v. injection of CD200-positive B16 melanoma cells dramatically inhibited tumor foci formation in the lungs of both C57BL/6 and Rag1⁻/⁻C57BL6 mice. Flow cytometry analysis revealed higher expression of CD200R in Gr1⁺ myeloid cells in the lung than in peripheral myeloid cells. Depletion of Gr1⁺ cells or stimulation of CD200R with an agonistic antibody in vivo dramatically inhibited tumor foci formation in the lungs. In addition, treatment with tumor antigen specific CD4 or CD8 T cells or their combination yielded a survival advantage for CD200 positive tumor bearing mice over mice bearing CD200-negative tumors. Taken together, we have revealed a novel role for CD200-CD200R interaction in inhibiting tumor formation and metastasis. Targeting CD200R may represent a novel approach for cancer immunotherapy.

  12. Results from Cu+Au collisions at 200 GeV in PHENIX Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Berdnikov, Ya. A.; Kotov, D. O.; Safonov, A. S. [Federal State Autonomous Educational Institution of Higher Education “Saint-Petersburg State Polytechnical University” (Russian Federation); Ivanishchev, D. A.; Riabov, V. G.; Riabov, Yu. G.; Samsonov, V. M. [Petersburg Nuclear Physics Institute B.P. Konstantinov, National Research Centre “Kurchatov Institute” (Russian Federation)

    2016-01-22

    Collisions of asymmetric nuclei (Cu+Au) differ essentially from the case of symmetric nuclei (Cu+Cu, Au+Au) collisions in the geometry of overlap region. This leads to a number of consequences, which provide more absolute and accurate information about fundamental properties of matter under extreme conditions. Nuclear modification factors for π-mesons in Cu+Au interactions at 200 GeV were measured in PHENIX Experiment at RHIC. New experimental data on measurement of flows of different order (v{sub 1}, v{sub 2}) for light hadrons in Cu+Au interactions at 200 GeV will be discussed in this paper.

  13. Effectiveness of the GT200 Molecular Detector: A Double-Blind Test

    CERN Document Server

    Mochán, W Luis

    2013-01-01

    The GT200 is a device that has been extensively used by the Mexican armed forces to remotely detect and identify substances such as drugs and explosives. A double blind experiment has been performed to test its effectivity. In seventeen out of twenty attempts, the GT200 failed in the hands of certified operators to find more than 1600 amphetamine pills and four bullets hidden in a randomly chosen cardboard box out of eight identical boxes distributed within a 90m$\\times$20m ballroom. This result is compatible with the 1/8 probability expected for a completely ineffectual device, and is incompatible with even a moderately effective working one.

  14. Always on the starting line: ELCAT 200 - the new-generation electric vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Baeckstroem, K.; Leisio, C. [ed.

    1997-11-01

    The Elcat 200 electric van can always be left charging. With most other electric van models, the situation is different. They run the risk of overcharging, which prevents continual `refuelling` of their batteries and thus considerably reduces the performance of the vehicles. The Elcat electric vehicle project has so far manufactured over 160 electric vans. Of these, the Elcat Cityvan accounts for 130, and the state-of-the-art Elcat 200 just over 30. The greatest single Elcat user is Finland Post, with 50 electric vehicles. Fifty Elcats have been sold abroad, most of them to Sweden

  15. Neutral water-chemical regime with hydrogen peroxide dosage at the AMB-200 unit

    International Nuclear Information System (INIS)

    Results of investigations related to estimation of erosion-corrosion process rates on feed water treatment with hydrogen peroxide at the Beloyarskaya NPP second unit are given. As follows from analysis, values of electric conductivity and iron oxide concentrations reduced two times as compared with correctionless regimes. Metal erosion rate in some feed water loop sections reduced 200-600 times. Hydrogen peroxide metering for feed water provides good condition and reliable operation of feed water loop equipment, reactor circuit and process tubes of the AMB-200 reactor unit

  16. New Technique for Re200c Catenary Construction on Hada Line%哈大线Re200C接触网工程施工新技术

    Institute of Scientific and Technical Information of China (English)

    朱飞雄

    2003-01-01

    通过借鉴和消化吸收国外的先进技术和施工管理经验,中铁电气化局在哈大线Re200C接触网施工中采用了许多新颖的技术和管理方法,本文介绍这些管理模式、施工特点、质量检测方法和施工允许偏差等.

  17. Hybrid Powered Vehicle kihaE200 of JR EAST%JR东日本公司kihaE200型混合动力车辆

    Institute of Scientific and Technical Information of China (English)

    大村哲朗; 石清伶

    2008-01-01

    JR东日本公司为了降低在非电气化区间运行的内燃动车对环境的污染,开发了内燃混合动力车辆,该车辆具有内燃发动机和蓄电池组合的动力系统,验证了该车辆在运营中的环境污染、蓄电池性能和维护性能.新造了批量生产用的样板车kihaE200型混合动力车辆.

  18. Clinical pathological analysis of 200 cases of salivary gland tumors%涎腺肿瘤200例临床病理分析

    Institute of Scientific and Technical Information of China (English)

    符攀峰

    2016-01-01

    Objective:To investigate the clinicopathological features of salivary gland tumors,and to improve the diagnostic accuracy.Methods:200 patients with salivary gland tumors were selected.We analyzed the place of occurrence,clinical symptoms and pathological diagnosis results.Results:The tumor occurring in the submandibular gland accounted for 26.0%,occurred in the sublingual gland accounted for 5.0%,occurred in oral accounted for 1.0%,occurred in the throat accounted for 0.5% in 200 cases of patients.The clinical symptoms of the patients in this group is mainly painless mass occurred in the part of salivary gland tumors,and the majority of patients with this tumor growth slow.In this group,132 cases were benign tumors,and the rest were malignant tumors.Conclusion:Salivary gland tumors likely occur in the parotid,submandibular and sublingual glands and other parts,more benign lesions,but we should judge the differentiation of benign and malignant tumors,which is conducive to the correct diagnosis and selection of treatment measures.%目的:探讨涎腺肿瘤的临床病理特点,提高其诊断正确率。方法:收治涎腺肿瘤患者200例。分析其发病部位、临床症状、病理诊断结果。结果:200例患者中肿瘤发生在腮腺67.5%、颌下腺26.0%、舌下腺5.0%、口腔1.0%、喉部0.5%。本组患者临床症状主要为涎腺肿瘤所在部位出现无痛性肿块、多数患者此肿块生长缓慢。本组患者中良性肿瘤132例,其余为恶性肿瘤。结论:涎腺肿瘤好发于腮腺、颌下腺及舌下腺等部位,良性病变较多,但要做好良恶性鉴别,利于正确诊断及选择治疗措施。

  19. 西门子S7 200 PLC在汽车上的应用%Applications of Siemens S7 200 PLC in Pumping Automobile

    Institute of Scientific and Technical Information of China (English)

    钱伟中

    2013-01-01

    主要介绍泵遥汽车液压系统中电器控制部分存在的一些问题,通过用TP178 Micro触摸屏和S7 200 PLC进行改造,使系统性能得到很大提高,尤其在泵送排量方面的控制性能更佳,为以后在这方面的开发提供参考和借鉴.

  20. Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine-200

    OpenAIRE

    Kovaleva, Elena G.; Rogers, Melanie S.; Lipscomb, John D.

    2015-01-01

    Kinetic and spectroscopic studies have shown that the conserved active site residue His200 of the extradiol ring-cleaving homoprotocatechuate 2,3-dioxygenase (FeHPCD) from Brevibacterium fuscum is critical for efficient catalysis. The roles played by this residue are probed here by analysis of the steady state kinetics, pH dependence, and X-ray crystal structures of the FeHPCD position 200 variants His200Asn, His200Gln, and His200Glu alone and in complex with three catecholic substrates (homo...

  1. NAL200 Series Level Compensator′s Adjustment Method%NAL200系列水准仪补偿器的调校方法

    Institute of Scientific and Technical Information of China (English)

    曹慧楠; 王健; 张太平

    2014-01-01

    This article introduced the NAL200 series level compensator the characteristics and working principle of the level and the compensator inspection and correction method, and gives the detail level, correction methods for basic indexes such as the adjustment of round bubble, I Angle error correction, the compensation accuracy of correction, compensator cross error correction and so on, in the process of measurement for the user to ensure the precision of the instrument to provide the reference.%介绍了NAL200系列水准仪的特点、水准仪工作原理以及补偿器检验和校正的方法,并详细给出了水准仪基本指标的校正方法,如圆水泡的调整、i角误差的校正、补偿精度的校正、补偿器交叉误差的校正等,为用户在进行测量过程中保证仪器的精度提供参考。

  2. The Movement Control of Manipulator Based on S7-200PLC%基于S7-200PLC的机械手运动控制

    Institute of Scientific and Technical Information of China (English)

    陈冬梅

    2014-01-01

    基于S7-200PLC对机械手的运动进行一系列控制,这些运动包括手臂上下、左右直线运动,手腕旋转运动,手爪夹紧动作和机械手整体旋转运动等。所采用的动力机构是步进电机,能够做到精确控制。在多个行程开关传感器的保护下,保证了这些运动万无一失。%The various movements of manipulator are controlled based on S7-200PLC. These movements include arms' up and down, left and right straight movements, wrist rotation, gripper clamping action and manipulator overall spin movement, etc. The power mechanism adopted is stepper motor, which can achieve precise control. Under the protection of multiple trip switch sensors, those movements are perfectly performed.

  3. 24 CFR 598.200 - Who nominates an area for designation?

    Science.gov (United States)

    2010-04-01

    ... DESIGNATIONS Nomination Procedure § 598.200 Who nominates an area for designation? Applicants for empowerment... the area is located, except as provided in §§ 598.500, 598.510, and 598.515. The nomination must be... of the designation process, and must contain complete and accurate information. (Approved by...

  4. Material erosion and erosion products in disruption simulation experiments at the MK-200 UG facility

    Energy Technology Data Exchange (ETDEWEB)

    Arkhipov, N.I.; Bakhtin, V.P.; Kurkin, S.M.; Safronov, V.M.; Toporkov, D.A.; Vasenin, S.G.; Zhitlukhin, A.M.; Wuerz, H. E-mail: hermann.wurz@ihm.fzk.de

    2000-11-01

    Plasma/material interaction was studied in disruption simulation experiments at the plasma gun facility MK-200 UG. Graphite, tungsten and aluminium targets (beryllium-like material) were irradiated by intense plasma streams under heat fluxes typical for international thermonuclear experimental reactor (ITER) hard disruption. Materials were also exposed to radiation emitted by target plasma shields. Surface damage and erosion products were analysed.

  5. 37 CFR 2.200 - Assignment records open to public inspection.

    Science.gov (United States)

    2010-07-01

    ... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...) are open to public inspection at the Office, and copies of those assignment records may be obtained... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Assignment records open...

  6. Strangelet search in S-W collisions at 200A GeV/c

    Science.gov (United States)

    Borer, K.; Dittus, F.; Frei, D.; Hugentobler, E.; Klingenberg, R.; Moser, U.; Pretzl, K.; Schacher, J.; Stoffel, F.; Volken, W.; Elsener, K.; Lohmann, K. D.; Baglin, C.; Bussière, A.; Guillaud, J. P.; Appelquist, G.; Bohm, C.; Hovander, B.; Selldèn, B.; Zhang, Q. P.

    1994-03-01

    A search for new massive particles with a low charge to mass ratio in S-W collisions at a beam momentum of 200 GeV/c per nucleon is presented. Upper limits for the production of strangelets with a mass to charge ratio of up to 60 GeV/c2 at rigidities of +/-150 GV are reported.

  7. Preparation and Dynamic Tensile Behavior of C200 Green Reactive Powder Concrete

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yunsheng; SUN Wei; LIU Sifeng; JIAO Chujie; LAI Jianzhong

    2006-01-01

    A new type of green reactive powder concrete (GRPC) with compressive strength of 200 MPa is prepared by utilizing composite mineral admixtures,natural fine aggregates,and short and fine steel fibers.The quasi-static mechanical properties (mechanical strength,toughness,fracture energy and interracial bonding strength) of GRPC specimens,cured in three different types of regimes,are investigated.The experimental results show that the mechanical properties of the C200 GRPC made with the powder binders that is composed of 40% of Portland cement,25% of ultra fine slag,25% of ultra fine fly ash and 10% of silica fume are better than the others'.The corresponding compressive strength,flexural strength and fracture energy are more than 200 MPa,and 30 000 J/m2 respectively.The dynamic tensile behavior of the C200 GRPC is also investigated through the split Hopkinson pressure bar (SHPB) according to the spalling phenomenon.The dynamic testing results demonstrate that strain rate has an important effect on the dynamic tensile behavior of GRPC.With the increase of strain rate,its peak stress and relevant strain increase.The GRPC exhibits an excellent strain ratio stiffening effect under the dynamic tensile Ioad with high strain ratio,resulting in a significant change of the fracture pattern.

  8. Increasing N200 Potentials Via Visual Stimulus Depicting Humanoid Robot Behavior.

    Science.gov (United States)

    Li, Mengfan; Li, Wei; Zhou, Huihui

    2016-02-01

    Achieving recognizable visual event-related potentials plays an important role in improving the success rate in telepresence control of a humanoid robot via N200 or P300 potentials. The aim of this research is to intensively investigate ways to induce N200 potentials with obvious features by flashing robot images (images with meaningful information) and by flashing pictures containing only solid color squares (pictures with incomprehensible information). Comparative studies have shown that robot images evoke N200 potentials with recognizable negative peaks at approximately 260 ms in the frontal and central areas. The negative peak amplitudes increase, on average, from 1.2 μV, induced by flashing the squares, to 6.7 μV, induced by flashing the robot images. The data analyses support that the N200 potentials induced by the robot image stimuli exhibit recognizable features. Compared with the square stimuli, the robot image stimuli increase the average accuracy rate by 9.92%, from 83.33% to 93.25%, and the average information transfer rate by 24.56 bits/min, from 72.18 bits/min to 96.74 bits/min, in a single repetition. This finding implies that the robot images might provide the subjects with more information to understand the visual stimuli meanings and help them more effectively concentrate on their mental activities.

  9. MiR-200b regulates autophagy associated with chemoresistance in human lung adenocarcinoma.

    Science.gov (United States)

    Pan, Banzhou; Feng, Bing; Chen, Yitian; Huang, Guichun; Wang, Rui; Chen, Longbang; Song, Haizhu

    2015-10-20

    Chemoresistance remains a major clinical problem in combating human lung adenocarcinoma (LAD), and abnormal autophagy is closely associated with this phenomenon. In the present study, an inverse correlation between miR-200b and autophagy-associated gene 12 (ATG12) expressions was observed in docetaxel-resistant (SPC-A1/DTX and H1299/DTX) and sensitive (SPC-A1 and H1299) LAD cells as well as in tissue samples. Further study showed that miR-200b directly targeted ATG12 in LAD. Moreover, miR-200b-dependent ATG12 downregulation inhibited autophagy and enhanced the chemosensitivity of SPC-A1/DTX and H1299/DTX cells both in vivo and in vitro. LAD chemoresistance is therefore closely related to downregulation of miR-200b and the corresponding upregulation of ATG12. These results provide new evidence for the mechanisms governing the microRNA (miRNA)-ATG12 network and their possible contribution to autophagy modulation and LAD chemoresistance.

  10. 33 CFR 162.200 - Marina del Rey, Calif.; restricted area.

    Science.gov (United States)

    2010-07-01

    ... dealing with this section in 33 CFR Part 207. ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Marina del Rey, Calif... SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.200...

  11. Genomic structure in Europeans dating back at least 36,200 years

    DEFF Research Database (Denmark)

    Seguin-Orlando, Andaine; Korneliussen, Thorfinn Sand; Sikora, Martin;

    2014-01-01

    The origin of contemporary Europeans remains contentious. We obtained a genome sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago, one of the oldest fossils of anatomically modern humans from Europe. We find that Kostenki 14 shares a close ancestry with the 24,000...

  12. Hainan’s 200,000-ton Uncoated Tinplate Base Project to Kick off

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Sources from NFC Hainan Nonferrous Metals Industry Co.,Ltd.indicated that,as a key project of Hainan,the 200,000-ton uncoated tinplate base project is expected to kick off in the first half of this year.Now,all preliminary works have been completed.Upon completion,

  13. Aulice to Build 1,200,000 Units/Y All- steel Tires Project

    Institute of Scientific and Technical Information of China (English)

    Li Zao

    2012-01-01

    To adapt to the rapid development of automobile industry and to meet the market demand on high- performance tires, upon investigation, Hubei Aulice Tire Co., Ltd. intends to build all-steel radial tire production project with the output of 1,200,000 units per year.

  14. Radiation emission from the "Rhodotron-TT200" cavity

    Institute of Scientific and Technical Information of China (English)

    Farshid Tabbakh; Mahmud Borhani

    2011-01-01

    In this paper, the X-rays emitted from the Rhodotron-TT200 cavity have been studied in depth. We found that the Bremsstrahlung interaction is the only contribution of X-ray generation important to safety. The X-ray dose rate in the Rhodotron vault is calc

  15. 29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Provisions governing inclusion, exclusion, and crediting of... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a... statutory exclusions are authorized. It is important to determine the scope of these exclusions, since...

  16. Identified particles in Au+Au collisions at S=200 GeV

    Science.gov (United States)

    Phobos Collaboration; Wosiek, Barbara; Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Ballintijn, M.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; García, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

    2003-03-01

    The yields of identified particles have been measured at RHIC for Au+Au collisions at S=200 GeV using the PHOBOS spectrometer. The ratios of antiparticle to particle yields near mid-rapidity are presented. The first measurements of the invariant yields of charged pions, kaons and protons at very low transverse momenta are also shown.

  17. 46 CFR 170.200 - Estimated lightweight vertical center of gravity.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Estimated lightweight vertical center of gravity. 170... Centers of Gravity § 170.200 Estimated lightweight vertical center of gravity. (a) Each tank vessel that... calculations required by §§ 170.170 and 172.065, the vertical center of gravity of a tank vessel in...

  18. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Disposition of business by... Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  19. 17 CFR 200.42 - Disposition of business by seriatim Commission consideration.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Disposition of business by... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.42 Disposition of business by seriatim Commission consideration. (a) Whenever...

  20. 17 CFR 200.40 - Joint disposition of business by Commission meeting.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Joint disposition of business... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.40 Joint disposition of business by Commission meeting. Any meeting of...

  1. Strangelet search in Au+Au collisions at VsNN=200 GeV

    NARCIS (Netherlands)

    Bai, Y.; Benedosso, F.; Botje, M.A.J.; Grebenyuk, O.; Mischke, A.; Peitzmann, T.; Russcher, M.J.; Snellings, R.J.M.; van der Kolk, N.

    2007-01-01

    We have searched for strangelets in a triggered sample of 61 million central (top 4%) Au+Au collisions at √sNN=200 GeV near beam rapidities at the STAR solenoidal tracker detector at the BNL Relativistic Heavy Ion Collider. We have sensitivity to metastable strangelets with lifetimes of order ⩾0.1 n

  2. Increasing N200 Potentials Via Visual Stimulus Depicting Humanoid Robot Behavior.

    Science.gov (United States)

    Li, Mengfan; Li, Wei; Zhou, Huihui

    2016-02-01

    Achieving recognizable visual event-related potentials plays an important role in improving the success rate in telepresence control of a humanoid robot via N200 or P300 potentials. The aim of this research is to intensively investigate ways to induce N200 potentials with obvious features by flashing robot images (images with meaningful information) and by flashing pictures containing only solid color squares (pictures with incomprehensible information). Comparative studies have shown that robot images evoke N200 potentials with recognizable negative peaks at approximately 260 ms in the frontal and central areas. The negative peak amplitudes increase, on average, from 1.2 μV, induced by flashing the squares, to 6.7 μV, induced by flashing the robot images. The data analyses support that the N200 potentials induced by the robot image stimuli exhibit recognizable features. Compared with the square stimuli, the robot image stimuli increase the average accuracy rate by 9.92%, from 83.33% to 93.25%, and the average information transfer rate by 24.56 bits/min, from 72.18 bits/min to 96.74 bits/min, in a single repetition. This finding implies that the robot images might provide the subjects with more information to understand the visual stimuli meanings and help them more effectively concentrate on their mental activities. PMID:26621216

  3. A Dictionary of Russian Idioms and Colloquialisms; 2,200 Expressions with Examples.

    Science.gov (United States)

    Jaszczun, Wasyl; Krynski, Szymon

    Some 2,200 expressions with illustrative sentences in Russian are contained in this dictionary intended for use as a reference work by students in intermediate and advanced Russian studies. The idioms or colloquialisms are rendered into English and are derived primarily from the classics of Russian literature. The dictionary covers phraseological…

  4. Merelaevanduse erastamisega sai riik 200 miljoniga vastu pükse / Martin Hanson

    Index Scriptorium Estoniae

    Hanson, Martin, 1984-

    2006-01-01

    Ilmunud ka: Delovõje Vedomosti 28. juuni lk. 4-5. Eesti Merelaevanduse pankroti tõttu jääb Eesti riik ilma 200 miljonist kroonist. Vt. samas: Merelaevanduse kurbmäng; Sarnet: raha tulnuks kohe kätte nõuda; ESCO Shipping töötab edasi

  5. Eesti Raudtee võib narvalaste vastuseisu tõttu kaotada 200 miljonit krooni / Irina Tokareva

    Index Scriptorium Estoniae

    Tokareva, Irina

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 29. apr. 2008, lk. 3, Narvskaja Nedelja 30. apr. lk. 3. Narva linnavolikogu kinnitas häälteenamusega Eesti Raudtee territooriumi detailplaneeringu. Kui otsus jõustub, võib ettevõte jätkata Narva teelõigu rekonstrueerimist, millele on juba ligi 200 miljonit krooni kulutatud

  6. 200 000 krooniga tudengeid ei peibuta / Anneli Aasmäe

    Index Scriptorium Estoniae

    Aasmäe, Anneli, 1973-

    2007-01-01

    Küsitlus Tallinna Ülikooli tudengite hulgas näitas, et kehtima hakkav lähtetoetus pole nende ametivalikut mõjutanud, pigem näevad nad 200 000 krooni suuruses summas mitmesuguseid ohtusid. Vt. samas: Lühiintervjuu haridus- ja teadusminister Tõnis Lukasega

  7. Šveitsi firma plaanib investeerida Repo Vabrikutesse 200 miljonit krooni / Gerli Romanovitsh

    Index Scriptorium Estoniae

    Romanovitš, Gerli, 1977-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 1. sept. lk 1,3. AS-i Repo Vabrikud omanik, Šveitsi investeerimisfirma Sorbes AG, kellele kuulus 51% ettevõtte aktsiatest, ostis SEB Eesti Ühispangalt ka ülejäänud aktsiad ning plaanib ainuomanikuna investeerida puitplaaditööstusesse 200 miljonit krooni

  8. Euroopa Liit võtab Eestilt statistikaga 200 miljonit / Aivar Reinap

    Index Scriptorium Estoniae

    Reinap, Aivar, 1968-

    2004-01-01

    EL-i arvutusnõuete tõttu kasvas Eesti 2003. aasta SKP ligi 10 miljardi krooni võrra, mistõttu peab Eesti maksma igal aastal 200 miljoni võrra senisest rohkem liikmemaksu. Lisa: Pool miljardit lisaks

  9. The Lexus CT 200h shines at the eighth China Changchun International Auto Expo

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Lexus,the world’s leading luxury car producer,brought its CT200h and six more vehicles to display at the eighth China Changchun International Auto Expo in Changchun,capital of Northeast China’s Jilin Province on July14.

  10. 28 CFR 44.200 - Unfair immigration-related employment practices.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Unfair immigration-related employment... IMMIGRATION-RELATED EMPLOYMENT PRACTICES Prohibited Practices § 44.200 Unfair immigration-related employment practices. (a)(1) General. It is unfair immigration-related employment practice for a person or other...

  11. Measurements on the SPS 200 MHz Travelling Wave Cavity towards an Impedance Model

    CERN Document Server

    Roggen, Toon; Caspers, Fritz; Vollinger, Christine; CERN. Geneva. ATS Department

    2016-01-01

    This note discusses the contribution of the SPS 200 MHz TWC (Travelling Wave Cavity) to the SPS longitudinal impedance model. The measurement method and setup is briefly explained and a comparison with simulations is discussed for both the fundamental pass band (FPB) as well as the Higher Order Modes (HOMs). In addition a number of improvements to the measurement setup are discussed.

  12. 17 CFR 200.80f - Appendix F-Records control schedule.

    Science.gov (United States)

    2010-04-01

    ... ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Information and Requests § 200.80f Appendix F... (17 CFR 270.02), and related correspondence 6 years. 817- Report of repurchase of securities by closed... Reports of internal inquiries: 1. Supporting documentation Until date of final action plus 5 years, if...

  13. 45 CFR 2519.200 - How may grant funds be used?

    Science.gov (United States)

    2010-10-01

    ... COMMUNITY SERVICE HIGHER EDUCATION INNOVATIVE PROGRAMS FOR COMMUNITY SERVICE Use of Grant Funds § 2519.200 How may grant funds be used? Funds under a higher education program grant may be used for the following activities: (a) Enabling an institution of higher education, a higher education partnership or...

  14. 15 CFR 200.109 - Shipping, insurance, and risk of loss.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Shipping, insurance, and risk of loss..., SERVICES, PROCEDURES, AND FEES § 200.109 Shipping, insurance, and risk of loss. (a) Shipment of apparatus... as to minimize the likelihood of damage in shipment and handling. Suggestions on packing and...

  15. Radioactive liquid wastes discharged to ground in the 200 Areas during 1978

    International Nuclear Information System (INIS)

    This document is issued quarterly for the purpose of summarizing the radioactive liquid wastes that have been discharged to the ground in the 200 Areas. In addition to data for 1978, cumulative data since plant startup are presented. Also, in this document is a listing of decayed activity to the various plant sites

  16. 梅科A-200:南非海军的新中坚

    Institute of Scientific and Technical Information of China (English)

    陈安刚

    2006-01-01

    今年2月16日,南非海军在西蒙斯顿举行仪式,宣布向德国订购的4艘梅科A-200轻型护卫舰的首舰“阿玛托拉”号正式入役。梅科A-200的加盟标志着南非海军进入了现代化发展阶段。梅科A-200是为满足南非海军的需求而设计的。该级舰使用了德国MEKO(由德文“多用选标准舰”一词各单词头一个字母耕成)新技术,其显著特点是:采用模块化技术设计,舰艇信号特征大为降低,海上生存能力强等。在南非海军现役舰艇中,现代化程度最高.打击火力最猛、技术性能最好者非梅科A-200莫属。梅科A-290轻型护卫舰可说是南非现代海军的中坚,令人关注。

  17. Sigma*-mediated electronic relaxation in 200nm photoexcited ammonia and heteroaromatics

    Directory of Open Access Journals (Sweden)

    Evans N. L.

    2013-03-01

    Full Text Available Time–resolved photoelectron spectra of ammonia display combination bands of the umbrella and stretching modes associated with the N–H coordinate of σ* relaxation. Time–resolved photodissociation studies determine timescales <200fs. Similar σ* photochemistry is found in heteroaromatics

  18. Electrical Conductivity Of Diamond Up To 1,200 Degrees C

    Science.gov (United States)

    Vandersande, Jan W.; Zoltan, Leslie D.

    1993-01-01

    Report discusses measurements of electrical conductivities of two synthetic diamond films, three synthetic diamondlike films, and two natural type IIa diamonds at temperatures from ambient to 1,200 degrees C. Measurements performed to compare electrical conductivities of state-of-the-art diamond films with those of natural insulating diamond, particularly at temperatures above 700 degrees C.

  19. North versus South : Energy transition and energy intensity in Europe over 200 years

    NARCIS (Netherlands)

    Gales, Ben; Kander, Astrid; Malanima, Paolo; Rubio, Mar

    2007-01-01

    This article examines energy consumption in Sweden, Holland, Italy and Spain over 200 years, including both traditional and modern energy carriers. The analysis is based on totally new series of energy consumption including traditional carriers along with modern sources. Our main purposes are a clos

  20. Nouvelle application de control des cavités 200 MHz RF du PS (CERN)

    CERN Document Server

    Cotte, D

    2011-01-01

    Le système Radio Fréquence (RF) 200MHz du PS est un outil essentiel pour la préparation des faisceaux haute intensité du PS. Dans l’anneau PS on trouve 6 cavités 200 MHz utilisées pour contrôler : • l’émittance longitudinale des « bunches » • le processus de « Rebunching » du faisceau avant de l’envoyer au SPS. Chaque cavité est pilotée par des événements appelés « timing » et suit une fonction de tension programmée. Cependant, l’électronique utilisée pour piloter les cavités 200 MHz du PS est obsolète et sa fiabilité non garantie pour cause du manque de pièces de rechange. Ce document décrit le fonctionnement du nouveau programme d’application qui fait abstraction de l’ancienne matrice hardware. Elle suit les recommandations décrites dans l’étude d’une nouvelle structure pour le système RF 200MHz du PS. [1

  1. 20 CFR 200.5 - Protection of privacy of records maintained on individuals.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Protection of privacy of records maintained... ADMINISTRATION GENERAL ADMINISTRATION § 200.5 Protection of privacy of records maintained on individuals. (a... as his full name, date of birth, and social security number. The system manager shall respond to...

  2. Low-dose mifepristone 200 mg and vaginal misoprostol for abortion

    NARCIS (Netherlands)

    Schaff, EA; Eisinger, SH; Stadalius, LS; Franks, P; Gore, BZ; Poppema, S

    1999-01-01

    The objectives of this study were to determine the effectiveness, side effects, and acceptability of one-third the standard 600 mg dose of mifepristone (200 mg) to induce abortion. A prospective trial at seven sites enrolled women greater than or equal to 18 years, up to 8 weeks pregnant, and wantin

  3. Sodium-dependent inhibition by PN200-110 enantiomers of nicotinic adrenal catecholamine release.

    Science.gov (United States)

    Cárdenas, A. M.; Montiel, C.; Artalejo, A. R.; Sánchez-García, P.; García, A. G.

    1988-01-01

    1. Dimethylphenylpiperazinium (DMPP) or high K concentrations evoke catecholamine release from perfused cat adrenal glands; in both cases the secretory response was significantly enhanced in the absence of Na. Tetrodotoxin did not modify the nicotinic secretory response. 2. The (+)- and (-)-enantiomers of the dihydropyridine Ca channel blocker PN200-110 show a high degree of stereoselectivity in the inhibition of catecholamine secretion evoked by high K or by DMPP in the presence of Na, the (+)-enantiomer being 57 and 80 times more potent, respectively, than the (-)-enantiomer. Both, noradrenaline and adrenaline release were equally depressed by PN200-110. 3. The IC50 values for (+)- and (-)-PN200-110 for blockade of the secretory response induced by K or DMPP in the presence of Na are in the same range. In the absence of Na, (-)-PN200-110 did not affect DMPP-evoked secretion; however, the (+)-enantiomer partially inhibited it. 4. The results suggest that the physiological catecholamine release from chromaffin cells is preceded by Na entry through the nicotinic receptor-associated ionophore; this causes cell depolarization, opening of voltage-dependent, dihydropyridine-sensitive Ca channels and Ca entry into the cell. In the absence of Na, additional Ca influx through an alternative pathway (the nicotinic cholinoceptor ionophore?) might also activate secretion. PMID:2975522

  4. CHITINASE-B FROM SERRATIA-MARCESCENS-BJL200 IS EXPORTED TO THE PERIPLASM WITHOUT PROCESSING

    NARCIS (Netherlands)

    BRURBERG, MB; EIJSINK, VGH; HAANDRIKMAN, AJ; VENEMA, G; NES, IF

    1995-01-01

    A gene encoding a chitinase from Serratia marcescens BJL200 was cloned and expressed in Escherichia coli and S. marcescens. Nucleotide sequencing revealed an open reading frame encoding a 55.5 kDa protein of 499 amino acids without a typical signal peptide for export. The cellular localization of th

  5. Climate Prediction Center (CPC) Area-average 200-hPa Zonal Wind Anomalies

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This is one of the CPC?s Monthly Atmospheric and SST Indices. It is the 200-hPa zonal wind anomalies averaged over the area 5oN ? 5oS, 165oW-110oW. The anomalies...

  6. 76 FR 24351 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes

    Science.gov (United States)

    2011-05-02

    ... A340-200/-300 pre- modification 49203 (reinforcements of pylon primary structure for enhanced A340... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3. Will not have a significant economic impact, positive or negative, on a substantial number of small entities under the criteria of...

  7. Free electron laser irradiation at 200 microns affects DNA synthesis in living cells

    International Nuclear Information System (INIS)

    We describe the effect of a 200-microns wavelength free electron laser beam on the ability of asynchronized and synchronized mammalian tissue culture cells to incorporate tritiated thymidine. Compared to controls (unexposed cells), a significant proportion of exposed cells exhibited a reduction in isotope incorporation. The results suggest that this wavelength may affect DNA synthesis

  8. Ultrasound Screening for Deep Venous Thrombosis Detection: A Prospective Evaluation of 200 Plastic Surgery Outpatients

    OpenAIRE

    Eric Swanson, MD

    2015-01-01

    Background: Our understanding of the pathophysiology of venous thromboembolism is largely based on the experience of orthopedic patients undergoing total joint replacement. Little is known regarding the natural history of venous thromboembolism in plastic surgery outpatients. Today, ultrasound screening, including compression and Doppler color flow imaging, represents the standard for detecting deep venous thromboses. Methods: Ultrasound screening was offered to 200 consecutive plastic sur...

  9. 40 CFR 80.200 - What gasoline is subject to the sulfur standards and requirements?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false What gasoline is subject to the sulfur... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Gasoline Sulfur Standards § 80.200 What gasoline is subject to the sulfur standards and requirements? For the purpose...

  10. 18 CFR 260.200 - Original cost statement of utility property.

    Science.gov (United States)

    2010-04-01

    ...), (2) the cost of the acquiring company, (3) the amount entered in the books as of the date of...) § 260.200 Original cost statement of utility property. Any natural gas company becoming subject to the... development of the company, including, particularly, a description (giving names of parties and dates) of...

  11. Step Frequency and Step Length of 200-m Sprint in Able-bodied and Amputee Sprinters.

    Science.gov (United States)

    Hobara, H; Sano, Y; Kobayashi, Y; Heldoorn, T A; Mochimaru, M

    2016-02-01

    The goal of this study was to examine the hypothesis that the difference in the 200-m sprint performance of amputee and able-bodied sprinters is due to a shorter step length rather than a lower step frequency. Men's elite-level 200-m races with a total of 16 able-bodied, 13 unilateral transtibial, 5 bilateral transtibial, and 16 unilateral transfemoral amputee sprinters were analyzed from publicly available internet broadcasts. For each run, the average forward velocity, step frequency, and step length over the entire 200-m distance were analyzed for each sprinter. The average forward velocity of able-bodied sprinters was faster than that of the other 3 groups, but there was no significant difference in average step frequency between able-bodied and transtibial amputee sprinters. However, the average step length of able-bodied sprinters was significantly longer than that of the transtibial amputee sprinters. In contrast, the step frequency and step length of transfemoral amputees were significantly lower and shorter than those of the other 3 groups. These results suggest that the differences in 200-m sprint performance between able-bodied and amputee sprinters are dependent on amputation level.

  12. miR-200a-3p regulates TLR1 expression in bacterial challenged miiuy croaker.

    Science.gov (United States)

    Wang, Yanjin; Xu, Guoliang; Han, Jingjing; Xu, Tianjun

    2016-10-01

    MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs which post-transcriptionally regulate various biological processes by repressing mRNA translation or degradating mRNA. It has been demonstrated that miRNAs play crucial roles in regulating the immune system. In this study, we explored the potential roles of miR-200a-3p in regulating TLR signaling pathway in miiuy croaker. Bioinformatics analysis showed that miiuy croaker TLR1 (mmiTLR1) was a putative target of miR-200a-3p. Negative expression profiles in spleen of Vibrio anguillarum challenged miiuy croaker and in lipopolysaccharide (LPS) stimulated miiuy croaker leukocytes further validated the prediction. Luciferase reporter assays showed that the dual-luciferase reporter fused to the 3'UTR of wild type mmiTLR1 cotransfected with miR-200a-3p mimics exhibited a reduction in luciferase activity compared with the controls. All of the present data provide direct evidence that miR-200a-3p is involved in TLR1 expression modulation in miiuy croaker, which will offer a basis for better understanding of miRNA regulation in fish TLR signaling pathways. PMID:27288848

  13. Step Frequency and Step Length of 200-m Sprint in Able-bodied and Amputee Sprinters.

    Science.gov (United States)

    Hobara, H; Sano, Y; Kobayashi, Y; Heldoorn, T A; Mochimaru, M

    2016-02-01

    The goal of this study was to examine the hypothesis that the difference in the 200-m sprint performance of amputee and able-bodied sprinters is due to a shorter step length rather than a lower step frequency. Men's elite-level 200-m races with a total of 16 able-bodied, 13 unilateral transtibial, 5 bilateral transtibial, and 16 unilateral transfemoral amputee sprinters were analyzed from publicly available internet broadcasts. For each run, the average forward velocity, step frequency, and step length over the entire 200-m distance were analyzed for each sprinter. The average forward velocity of able-bodied sprinters was faster than that of the other 3 groups, but there was no significant difference in average step frequency between able-bodied and transtibial amputee sprinters. However, the average step length of able-bodied sprinters was significantly longer than that of the transtibial amputee sprinters. In contrast, the step frequency and step length of transfemoral amputees were significantly lower and shorter than those of the other 3 groups. These results suggest that the differences in 200-m sprint performance between able-bodied and amputee sprinters are dependent on amputation level. PMID:26509370

  14. 34 CFR 200.29 - Consolidation of funds in a schoolwide program.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Consolidation of funds in a schoolwide program. 200.29... Consolidation of funds in a schoolwide program. (a)(1) In addition to funds under subpart A of this part, a... IDEA for that fiscal year, divided by the number of children with disabilities in the jurisdiction...

  15. 21 CFR 200.15 - Definition of term “insulin.”

    Science.gov (United States)

    2010-04-01

    ...) DRUGS: GENERAL GENERAL General Provisions § 200.15 Definition of term “insulin.” For purposes of sections 801 and 802 of the act and this title, the term insulin means the active principle of the pancreas... the same as, or similar to, naturally occurring insulins in structure, use, and intended effect...

  16. 17 CFR 200.509 - Challenge to classification by Commission employees.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Challenge to classification by... COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Classification and Declassification of National Security Information and Material § 200.509 Challenge to classification by...

  17. Structure on large scale in the universe up to the distance of 200 Mpc

    CERN Document Server

    Di Nella, H; Di Nella, Helene; Paturel, Georges

    1995-01-01

    The distribution of galaxies up to a distance of 200 Mpc (650 million light-years) is flat and shows a structure like a shell roughly centered on the Local Supercluster (Virgo cluster). This result clearly confirms the existence of the hypergalactic large scale structure noted in 1988. This is presently the largest structure ever seen.

  18. 46 CFR 174.200 - Damaged stability in machinery spaces for all OSVs.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Damaged stability in machinery spaces for all OSVs. 174... Vessels § 174.200 Damaged stability in machinery spaces for all OSVs. Each OSV must be shown by design... case of damage between any two watertight bulkheads in each machinery space....

  19. 21 CFR 107.200 - Food and Drug Administration-required recall.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Food and Drug Administration-required recall. 107... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION INFANT FORMULA Infant Formula Recalls § 107.200 Food and Drug Administration-required recall. When the Food and Drug Administration determines that...

  20. DESCRIPTION OF MODELING ANALYSES IN SUPPORT OF THE 200-ZP-1 REMEDIAL DESIGN/REMEDIAL ACTION

    Energy Technology Data Exchange (ETDEWEB)

    VONGARGEN BH

    2009-11-03

    The Feasibility Study/or the 200-ZP-1 Groundwater Operable Unit (DOE/RL-2007-28) and the Proposed Plan/or Remediation of the 200-ZP-1 Groundwater Operable Unit (DOE/RL-2007-33) describe the use of groundwater pump-and-treat technology for the 200-ZP-1 Groundwater Operable Unit (OU) as part of an expanded groundwater remedy. During fiscal year 2008 (FY08), a groundwater flow and contaminant transport (flow and transport) model was developed to support remedy design decisions at the 200-ZP-1 OU. This model was developed because the size and influence of the proposed 200-ZP-1 groundwater pump-and-treat remedy will have a larger areal extent than the current interim remedy, and modeling is required to provide estimates of influent concentrations and contaminant mass removal rates to support the design of the aboveground treatment train. The 200 West Area Pre-Conceptual Design/or Final Extraction/Injection Well Network: Modeling Analyses (DOE/RL-2008-56) documents the development of the first version of the MODFLOW/MT3DMS model of the Hanford Site's Central Plateau, as well as the initial application of that model to simulate a potential well field for the 200-ZP-1 remedy (considering only the contaminants carbon tetrachloride and technetium-99). This document focuses on the use of the flow and transport model to identify suitable extraction and injection well locations as part of the 200 West Area 200-ZP-1 Pump-and-Treat Remedial Design/Remedial Action Work Plan (DOEIRL-2008-78). Currently, the model has been developed to the extent necessary to provide approximate results and to lay a foundation for the design basis concentrations that are required in support of the remedial design/remediation action (RD/RA) work plan. The discussion in this document includes the following: (1) Assignment of flow and transport parameters for the model; (2) Definition of initial conditions for the transport model for each simulated contaminant of concern (COC) (i.e., carbon

  1. Feasibility study report for the 200-BP-1 operable unit. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    This feasibility study (FS) examines a range of alternatives and provides recommendations for selecting a preferred altemative for remediating contamination at the 200-BP-1 operable unit. The 200-BP-1 operable unit is located in the center of the Hanford Site along the northern boundary of the 200 East Area. The 241-BY Tank Farm is located immediately to the south of the operable unit. 200-BP-1 is a source operable unit with contaminated soils associated primarily with nine inactive cribs (known as the 216-B cribs). These cribs were used for disposal of low-level radioactive liquid waste from U Plant uranium recovery operations, and waste storage tank condensate from the adjacent 241-BY Tank Farm. The cribs used for disposal of U Plant waste were in operation from 1955--1965, and the cribs used for disposal of tank condensate were in operation from 1965-1975. In addition to the cribs, four unplanned releases of radioactive materials have occurred within the operable unit. Contaminated surface soils associated with the unplanned releases have been consolidated over the cribs and covered with clean soil to reduce contaminant migration and exposure. Discharge of wastes to the cribs has resulted in soil and groundwater contamination. The groundwater is being addressed as part of the 200 East Aggregate Area groundwater operable unit. Contaminated soils at the site can be categorized by the types of contaminants, their distribution in the soil column, and the risk posed by the various potential exposure pathways. Below the clean soil cover, the near surface soils contain low-:levels of contamination with cesium-137, radium-226, strontium-90, thorium-228 and uranium. The lifetime incremental cancer risk associated with these soils if they were exposed at the surface is 9 {times} 10{sup 5}.

  2. 200例小儿热性惊厥的脑电图分析%Analysis of EEG in 200 patients with febrile convulsion

    Institute of Scientific and Technical Information of China (English)

    李爱党; 李琼仙

    2007-01-01

    目的:探讨脑电图(EEG)与小儿热性惊厥的关系.方法:应用EEG检测200例6个月至12岁热性惊厥患儿.结果:年龄≤2岁组与>2岁组,体温>38.5℃与≤38.5℃组比较,后者EEG异常率明显高于前者(P<0.05).结论:对年龄>2岁,体温≤38.5℃且反复发作的小儿热性惊厥必须引起足够重视,对EEG异常和有癫痫样放电的患儿均应酌情投以抗癫痫药物治疗.

  3. 200个保健食品、食品宣传广告的调查%Survey on 200 Kinds of Functional Food and Advertisements

    Institute of Scientific and Technical Information of China (English)

    董东风; 李光宗

    2001-01-01

    @@ 保健食品、食品广告违法问题,已引起社会各界的强烈不满,近期已列为整顿和规范市场经济秩序工作的重要内容之一.保健食品、食品广告直接关系到广大人民群众的切身利益和生命安全,为从根本上制止违法的保健食品、食品广告,对某报发布的200个保健食品、食品广告进行了调查,针对保健食品、食品广告中存在的问题,提出改进意见.

  4. 200 Open Heart Operations on Patients with Ventricular Septal Defects%200例室间隔缺损(VSD)手术体会

    Institute of Scientific and Technical Information of China (English)

    李仲智; 郑德珍; 高玲; 郭志和; 高国庆; 陆进; 姜娟; 刘岚

    1989-01-01

    Two hundred open heart operations for VSD were performed between 1979.8 and 1987.5.77% of the patients aged below 5 years,and 68% weighed below 15kg and 16% below 10kg.98 out of 163(60%),on whom cardiac catherization was performed,showed moderate or severe pulmonary hypertension.197 patients su cvived,and 3 died duting hospitalization.Discussions involve:1) The age for operation.Patients with large defects and henrt failure;or repeated infection of respivatory tract,or hyposomia should be operated on earlier,better before the age of 2 years.As for patients with small defects operationts may be delayed to Presehool age.2) The type of operation.The defect with a diameter bigger than 1cm should be patched.The pladget mattress suture gives a better security sealing than the simple running suture does.3) The treatment of the associated cardiac deformities.PDA may be ligated before or after the cardiopulmonary bypass.4) The consi derations of a re-operation.Based on the experiences of 2 successful re-operations,it is suggested that in case of a serious complication responding Poorly to the medicaltreatmeat,a re-operation had better not be hesitated.%作者自1979年8月至1987年5月共进行了200例VSD心内直视手术,其中5岁以下占77%,体重15公斤以下占68%.手术取得良好的效果,存活率达到98.5%. 通过200例VSD手术经验,作者从手术时机的选择,修补方法的选择,合并畸形的处理以及再手术的决定等四个方面谈谈体会.

  5. 200名伤残荣誉军人牙周病调查分析%Investigation and anlysis of periodontal disease for 200 disabled soldiers

    Institute of Scientific and Technical Information of China (English)

    郭洁瑜; 李文利

    2013-01-01

    Objective: To understand the current situation of hospitalized disabled soldiers with periodontal disease, and explore the causes. Methods:Doctors-in-charge in Department of Stomatology examine 200 disabled soldiers with periodontal disease, enquire and record patients’ oral hygiene behaviors and bad habits. Results:The oral hygiene habit of disabled soldiers is worse. The prevalence rate of periodontitis is 59.5%, and the prevalence rate of gingivitis is 25.5%. Conclusion:The periodontal disease of hospitalized disabled soldiers is serious. We should strengthen the publicity of oral health knowledge, enhance the awareness of oral rights for disabled soldiers, and increase the initiative of protecting rights. Only in this way can the periodontal health level of disabled soldiers goes up radical y.%目的:了解住院伤残荣誉军人牙周病现状,并探索其形成原因。方法:由口腔科主治医师对200名伤残荣誉军人进行牙周病诊查,询问并记录患者的口腔卫生行为和不良嗜好。结果:伤残荣誉军人的口腔卫生习惯较差,牙周炎患病率为59.5%,牙龈炎的患病率为25.5%。结论:住院伤残荣誉军人牙周病严重,加强对其宣传口腔保健常识,增强伤残荣誉军人口腔维护意识,提高口腔维护的主动性,方可从根本上提高伤残荣誉军人的牙周健康水平。

  6. 200例主观性耳鸣患者听力损失临床分析%Study of hearing loss in 200 patients with subjective tinnitus

    Institute of Scientific and Technical Information of China (English)

    唐建辉; 吉彬; 刘立中

    2011-01-01

    目的:对耳鸣患者的听力损失进行分析,为进一步探讨耳鸣的发病原因、检查方法提供临床依据.方法:对以主观性耳鸣为主诉的200例患者进行耳科专科检查、声导抗检测、常频纯音听阈测听和高频扩展听阈测听检查.结果:200例耳鸣患者中,单侧耳鸣123例(61.5%),双侧耳鸣77例(38.5%);46例(23.0%)听力正常.单侧耳鸣中,患侧与对侧听阈比较0.125~8 kHz差异有统计学意义(P0.05).常频听力正常组与听力异常组比较各频率阈值差异均具有统计学意义(均P 10 kHz), the difference between two groups was not statistically significant (P > 0.05). There was significant difference in hearing threshold between tinnitus patients with normal and abnormal hearing in normal frequency(P<0. 05) ,meantime the detection rate in abnormal hearing group was lower than the normal group. Conclusion:Tinnitus can occur in people with normal hearing. Early in tinnitus,further study need be undertaken on whether the audiometry extended high frequency can offer the early evidence of hearing loss for tin-nitus patients or not.

  7. Pilot-scale treatability test plan for the 200-BP-5 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This document presents the treatability test plan for pilot-scale pump and treat testing at the 200-BP-5 Operable Unit. This treatability test plan has been prepared in response to an agreement between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology), as documented in Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1989a) Change Control Form M-13-93-03 (Ecology et al. 1994) and a recent 200 NPL Agreement Change Control Form (Appendix A). The agreement also requires that, following completion of the activities described in this test plan, a 200-BP-5 Operable Unit Interim Remedial Measure (IRM) Proposed Plan be developed for use in preparing an Interim Action Record of Decision (ROD). The IRM Proposed Plan will be supported by the results of this treatability test plan, as well as by other 200-BP-5 Operable Unit activities (e.g., development of a qualitative risk assessment). Once issued, the Interim Action ROD will specify the interim action(s) for groundwater contamination at the 200-BP-5 Operable Unit. The treatability test approach is to conduct a pilot-scale pump and treat test for each of the two contaminant plumes associated with the 200-BP-5 Operable Unit. Primary contaminants of concern are {sup 99}Tc and {sup 60}Co for underwater affected by past discharges to the 216-BY Cribs, and {sup 90}Sr, {sup 239/240}Pu, and Cs for groundwater affected by past discharges to the 216-B-5 Reverse Well. The purpose of the pilot-scale treatability testing presented in this testplan is to provide the data basis for preparing an IRM Proposed Plan. To achieve this objective, treatability testing must: Assess the performance of groundwater pumping with respect to the ability to extract a significant amount of the primary contaminant mass present in the two contaminant plumes.

  8. MiR-200 modulates coelomocytes antibacterial activities and LPS priming via targeting Tollip in Apostichopus japonicus.

    Science.gov (United States)

    Lv, Zhimeng; Li, Chenghua; Zhang, Pengjuan; Wang, Zhenhui; Zhang, Weiwei; Jin, Chun-Hua

    2015-08-01

    In order to explore the potential roles of microRNAs (miRNAs) in regulating Toll-like receptor (TLR) pathways, we identified Toll interacting protein as a putative target of miR-200 in Apostichopus japonicus coelomocytes by RNA-seq screening (denoted as AjTollip). The positive expression profiles of miR-200 and AjTollip were detected in both LPS exposure primary coelomocytes and Vibrio splendidus challenge sea cucumber. Co-infection miR-200 mimics significantly elevated the expression of AjTollip and its down-stream molecules. In contrast, miR-200 inhibitor significantly repressed the expression of these TLR-pathway members. More importantly, miR-200 displayed not only to enhance coelomocytes antibacterial activities, but to suppress LPS priming in vitro. Overall, all these results will enhance our understanding on miR-200 regulatory roles in anti-bacterial process in sea cucumber. PMID:25910848

  9. Development of the Pico Star Tracker ST-200 – Design Challenges and Road Ahead

    OpenAIRE

    Segert, Tom; Engelen, Steven; Buhl, Matthias; Monna, Bert

    2011-01-01

    The Pico Star Tracker ST-200 under development by Berlin Space Technologies GmbH (BST) is specifically designed keeping the limitations of CubeSats in mind. It comes in a compact 29x29x37mm³ package. It weights 74g and has a power consumption of 220mW average (620mW peak). The ST-200 offers a set of standard interfaces (I²C, SPI, RS485, RS232) and accepts input voltages of 3.3 to 5V. It can detect stars with a limiting magnitude of 6 and has an accuracy of 30 arc seconds (~0.01°). Using its i...

  10. Groundwater impact assessment report for the 216-S-26 Crib, 200 West Area

    Energy Technology Data Exchange (ETDEWEB)

    Lindberg, J.W.; Evelo, S.D.; Alexander, D.J.

    1993-11-01

    This report assesses the impact of wastewater discharged to the 216-S-26 Crib on groundwater quality. The 216-S-26 Crib, located in the southern 200 West Area, has been in use since 1984 to dispose of liquid effluents from the 222-S Laboratory Complex. The 222-S Laboratory Complex effluent stream includes wastewater from four sources: the 222-S Laboratory, the 219-S Waste Storage Facility, the 222-SA Chemical Standards Laboratory, and the 291-S Exhaust Fan Control House and Stack. Based on assessment of groundwater chemistry and flow data, contaminant transport predictions, and groundwater chemistry data, the 216-S-26 Crib has minimal influence on groundwater contamination in the southern 200 West Area.

  11. Revised Methodology for Determining Cesium-137 Content of HN-200 Grout Containers

    Energy Technology Data Exchange (ETDEWEB)

    SHELOR, J.L.

    1999-08-31

    The purpose of this technical paper is to examine the accuracy of the existing method of determining the Cs-137 content of HN-200 grout containers and compare that accuracy to the accuracy attainable by other methods of measurement. The methods of measurement to be compared include: Contact measurements on a grouted container (existing method); Measurements at 5 feet from the surface of a grouted container; Measurements at 10 feet from a grouted container; Measurements on contact with the surface of an ungrouted container; Measurements at 5 feet from the surface of an ungrouted container; and Measurements at 10 feet from the surface of an ungrouted container. Once the most accurate and useable method is determined, the precepts for an operating procedure will be provided for determining the Cs-137 content of newly generated and future HN-200 grout containers as well as the grouted legacy containers currently stored in B Cell.

  12. Treatment of 200 Cases of Asthma by Fat-cut Therapy

    Institute of Scientific and Technical Information of China (English)

    ZHANG Su-ya

    2005-01-01

    After local anesthesia, the skin of Shanzhong (CV 17) was incised 2 cm in length to expose the subcutaneous fat fully, and after cutting away local fat, the handle of the forceps was used inside the incision directly for stimulation and then the incision was sutured. In 200 cases of asthma patients, 100 cases were cured, and 95 cases were improved and 5 cases failed, with the effective rate in 97.5%.%取膻中穴,局部麻醉后,切开皮肤2cm,充分暴露皮下脂肪.割去局部脂肪在切口内直接用镊柄作手法刺激,然后缝合伤口.200例哮喘患者中治愈100例,好转95例,无效5例,总有效率97.5%.

  13. Summary of radioactive solid waste received in the 200 areas during calendar year 1997

    Energy Technology Data Exchange (ETDEWEB)

    Hagel, D.L.

    1998-06-25

    Waste Management Federal Services of Hanford Inc. manages and operates the Hanford Site 200 Area radioactive solid waste storage and disposal facilities for the US Department of Energy, Richland Operations Office under contract DE-AC06-87RL10930. These facilities include storage areas and disposal sites for radioactive solid waste. This document summarizes the amount of radioactive materials that have been buried and stored in the 200 Area radioactive solid waste storage and disposal facilities from startup in 1944 through calendar year 1997. This report does not include backlog waste, solid radioactive wastes in storage or disposed of in other areas, or facilities such as the underground tank farms. Unless packaged within the scope of WHC-EP-0063, Hanford Site Solid Waste Acceptance Cafeteria, liquid waste data are not included in this document.

  14. Summary of radioactive solid waste received in the 200 areas during calendar year 1996

    Energy Technology Data Exchange (ETDEWEB)

    Hladek, K.L.

    1997-05-21

    Rust Federal Services of Hanford Inc. manages and operates the Hanford Site 200 Area radioactive solid waste storage and disposal facilities for the US Department of Energy, Richland Operations Office under contract DE-AC06-87RL10930. These facilities include storage areas and disposal sites for radioactive solid waste. This document summarizes the amount of radioactive materials that have been buried and stored in the 200 Area radioactive solid waste storage and disposal facilities from startup in 1944 through calendar year 1996. This report does not include backlog waste, solid radioactive wastes in storage or disposed of in other areas, or facilities such as the underground tank farms. Unless packaged within the scope of WHC-EP-0063, Hanford Site Solid Waste Acceptance Criteria, liquid waste data are not included in this document.

  15. Summary of radioactive solid waste received in the 200 Areas during calendar year 1994

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, J.D.; Hagel, D.L.

    1995-08-01

    Westinghouse Hanford Company manages and operates the Hanford Site 200 Area radioactive solid waste storage and disposal facilities for the US Department of Energy, Richland Field Office, under contract DE-AC06-87RL10930. These facilities include radioactive solid waste disposal sites and radioactive solid waste storage areas. This document summarizes the amount of radioactive material that has been buried and stored in the 200 Area radioactive solid waste storage and disposal facilities from startup in 1944 through calendar year 1994. This report does not include backlog waste: solid radioactive wastes in storage or disposed of in other areas or facilities such as the underground tank farms. Unless packaged within the scope of WHC-EP-0063, Hanford Site Solid Waste Acceptance Criteria (WHC 1988), liquid waste data are not included in this document.

  16. COMBINED TREATMENT OF 200CASES OF PERIPHERY FACIAL PARALYSIS WITH ACUPUNCTURE AND CHINESE MEDICINAL HERBS

    Institute of Scientific and Technical Information of China (English)

    LuoHeping

    2000-01-01

    In the present study,200cases of periphery facial paralysis were treated with combined therapies of handle needle,electroacupuncture(EA),electronic moxibustion and oral administration of Supplemented Qianzheng San.After treatment,of the200cases,176were cured,15had marked im-provement and 9had improvement.Two groups of acupoints were chosen and used alternately for keeping the excitement of acupoints,preventing acupoint fatigue and raising the therapeutic effect.In the acute stage of periphery facial palsy,acupuncture treatment was performed using shallow needing,mild manipulation and no needing penetration.In the convalescence stage and sequela stage,penetra-tion needling was adopted and stronger stimulation given.During acute period and when facial muscu-lar spasm appeared,EA stimulation was not suitable for facial acupoints.Over use of vision should be avoided.

  17. Relativistic analysis of nuclear ground state densities at 135 to 200 MeV

    Indian Academy of Sciences (India)

    M A Suhail; N Neeloffer; Z A Khan

    2005-12-01

    A relativistic analysis of p + 40Ca elastic scattering with different nuclear ground state target densities at 135 to 200 MeV is presented in this paper. It is found that the IGO densities are more consistent in reproducing the data over the energy range considered here. The reproduction of spin-rotation-function data with the simultaneous fitting of differential cross-section and analyzing power, and the appearance of wine-bottle-bottom shaped Re eff() in the transition energy region, sensitively depends on the input nuclear ground state densities and are not solely the relativistic characteristic signatures. We also found that the wine-bottle-bottom shaped Re eff() is preferred by the spin observables in the transition energy region (i.e. 181 MeV to 200 MeV).

  18. Groundwater impact assessment report for the 216-S-26 Crib, 200 West Area

    International Nuclear Information System (INIS)

    This report assesses the impact of wastewater discharged to the 216-S-26 Crib on groundwater quality. The 216-S-26 Crib, located in the southern 200 West Area, has been in use since 1984 to dispose of liquid effluents from the 222-S Laboratory Complex. The 222-S Laboratory Complex effluent stream includes wastewater from four sources: the 222-S Laboratory, the 219-S Waste Storage Facility, the 222-SA Chemical Standards Laboratory, and the 291-S Exhaust Fan Control House and Stack. Based on assessment of groundwater chemistry and flow data, contaminant transport predictions, and groundwater chemistry data, the 216-S-26 Crib has minimal influence on groundwater contamination in the southern 200 West Area

  19. The CO poisoning effect in PEMFCs operational at temperatures up to 200 degrees C

    DEFF Research Database (Denmark)

    Li, Qingfeng; He, Ronghuan; Gao, Ji-An;

    2003-01-01

    The CO poisoning effect on carbon-supported platinum catalysts (at a loading of 0.5 mg Pt/cm(2) per electrode! in polymer electrolyte membrane fuel cells (PEMFCs) has been investigated in a temperature range from 125 to 200 degreesC with the phosphoric acid-doped polybenzimidazole membranes as el...... and temperature. The effect of CO2 in hydrogen was also studied. At 175 degreesC, 25% CO2 in the fuel stream showed only the dilution effect. (C) 2003 The Electrochemical Society.......The CO poisoning effect on carbon-supported platinum catalysts (at a loading of 0.5 mg Pt/cm(2) per electrode! in polymer electrolyte membrane fuel cells (PEMFCs) has been investigated in a temperature range from 125 to 200 degreesC with the phosphoric acid-doped polybenzimidazole membranes...

  20. Shrub-inhabiting insects of the 200 Area Plateau, southcentral Washington.

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, L.E.

    1979-10-01

    This study characterizes the insects (including spiders) associated with major shrubs of the 200 Area Plateau on the Hanford Site in southcentral Washington. Big sagebrush (Artemisia tridentata), rabbitbrush (Chrysothamnus sp.) and hopsage (Grayia spinosa) were the three shrubs included in the study. Hemiptera (true bugs) and homoptera (bugs) were the two groups most abundant on sagebrush. Homoptera and Araneida (spiders) were the common inhabitants of rabbitbrush, and Orthoptera (grasshoppers), Coleoptera (beetles), and Araneida the taxa most frequently collected from hopsage. A discussion of the effects of insects on western native shrubs is included. None of the insect populations appeared to threaten the stability of shrub stands, which is important because of the erodability of 200 Area soils.